CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048431	Staphylococcus aureus strain SA1428 chromosome, complete genome	9 crisprs	csa3,cas3,DinG,DEDDh,WYL	8	1	209	1
NZ_CP048432	Staphylococcus aureus strain SA1428 plasmid p1	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048431_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_1

283386-283470

Orphan

Consensus_repeat	Method
CCCACCCCAACTTGCATGGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_1

>merge|NZ_CP048431|1|283386-283470|CRISPRCasFinder
CCCACCCCAACTTGCATGGTCTGTAGAATTTCTTTTCGAAATTCTCTATGTTGGGGCCCCACCCCAACTTGCATTGTCTGTAGAA

>NZ_CP048431|1|1|283386-283470|CRISPRCasFinder
CCCACCCCAACTTGCATGGTCTGTAGAA	TTTCTTTTCGAAATTCTCTATGTTGGGGC
CCCACCCCAACTTGCATTGTCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000161674.1\|279141_280197_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NZ_CP048431.1\|WP_000471571.1\|289766_290624_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_CP048431.1\|WP_000123164.1\|299787_301056_+\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_CP048431.1\|WP_001789984.1\|278949_279048_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164025801.1\|291836_292805_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_CP048431.1\|WP_000689998.1\|277707_278826_+\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_CP048431.1\|WP_000136253.1\|273966_274461_+\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP048431.1\|WP_164025804.1\|296908_298270_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP048431.1\|WP_000883648.1\|290623_291568_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_CP048431.1\|WP_164025794.1\|283733_284675_+\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_CP048431.1\|WP_000040063.1\|275618_276821_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP048431.1\|WP_164025797.1\|288342_289572_+\|NAD-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|235976
NZ_CP048431.1\|WP_000829167.1\|298617_299739_+\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_CP048431.1\|WP_000160435.1\|281983_283282_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_CP048431.1\|WP_001232648.1\|292826_294584_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_CP048431.1\|WP_000634175.1\|277066_277567_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP048431.1\|WP_164025792.1\|281365_281779_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_CP048431.1\|WP_000777190.1\|280371_281061_+\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_CP048431.1\|WP_000840581.1\|274583_275531_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_CP048431.1\|WP_001836688.1\|284695_287893_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000161674.1\|279141_280197_-\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	9.25455e-126
NZ_CP048431.1\|WP_000471571.1\|289766_290624_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_CP048431.1\|WP_000123164.1\|299787_301056_+\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_CP048431.1\|WP_164025801.1\|291836_292805_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_CP048431.1\|WP_000689998.1\|277707_278826_+\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_CP048431.1\|WP_000136253.1\|273966_274461_+\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NZ_CP048431.1\|WP_164025804.1\|296908_298270_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP048431.1\|WP_000883648.1\|290623_291568_+\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_CP048431.1\|WP_164025794.1\|283733_284675_+\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	3.98146e-98
NZ_CP048431.1\|WP_000040063.1\|275618_276821_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP048431.1\|WP_164025797.1\|288342_289572_+\|NAD-dependent-malic-enzyme	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_CP048431.1\|WP_000829167.1\|298617_299739_+\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_CP048431.1\|WP_000160435.1\|281983_283282_+\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_CP048431.1\|WP_001232648.1\|292826_294584_+\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_CP048431.1\|WP_000634175.1\|277066_277567_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_CP048431.1\|WP_164025792.1\|281365_281779_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	2.63749e-18
NZ_CP048431.1\|WP_000777190.1\|280371_281061_+\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	1.10209e-133
NZ_CP048431.1\|WP_000840581.1\|274583_275531_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	2.58634e-57
NZ_CP048431.1\|WP_001836688.1\|284695_287893_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0

>NZ_CP048431.1|WP_000160435.1|281983_283282_+|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_CP048431.1|WP_164025792.1|281365_281779_-|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIRAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_CP048431.1|WP_000777190.1|280371_281061_+|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKVNFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_CP048431.1|WP_000161674.1|279141_280197_-|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLTSGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIILEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_CP048431.1|WP_001789984.1|278949_279048_+|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NZ_CP048431.1|WP_000689998.1|277707_278826_+|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_CP048431.1|WP_000634175.1|277066_277567_-|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_CP048431.1|WP_000040063.1|275618_276821_+|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NZ_CP048431.1|WP_000840581.1|274583_275531_+|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEADIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINVLKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_CP048431.1|WP_000136253.1|273966_274461_+|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI
>NZ_CP048431.1|WP_164025794.1|283733_284675_+|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNINDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NZ_CP048431.1|WP_001836688.1|284695_287893_+|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQDVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEVNQLDINQEYLTQVDVIAQKCNAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKKTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQKGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVMLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_CP048431.1|WP_164025797.1|288342_289572_+|NAD-dependent-malic-enzyme
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKYIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_CP048431.1|WP_000471571.1|289766_290624_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_CP048431.1|WP_000883648.1|290623_291568_+|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_CP048431.1|WP_164025801.1|291836_292805_+|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLKLGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_CP048431.1|WP_001232648.1|292826_294584_+|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_CP048431.1|WP_164025804.1|296908_298270_-|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVSGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NZ_CP048431.1|WP_000829167.1|298617_299739_+|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_CP048431.1|WP_000123164.1|299787_301056_+|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK

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Crispr_ID: NZ_CP048431_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_2

791228-791311

Unclear

Consensus_repeat	Method
TTTCGAAATTCTCTGTGTTGGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_2

>merge|NZ_CP048431|2|791228-791311|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>NZ_CP048431|2|2|791228-791311|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGGCCC	ACACCCCAACTCGCATTGCCTGTAGAATTTCT
TTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_001557331.1\|780835_782911_-\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|235516
NZ_CP048431.1\|WP_164025908.1\|785210_786377_-\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NZ_CP048431.1\|WP_000687328.1\|792050_792788_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl\|CDD\|234581
NZ_CP048431.1\|WP_000043237.1\|800863_801595_-\|ribonuclease-III	unknown	unknown	gnl\|CDD\|234633
NZ_CP048431.1\|WP_000236722.1\|787236_788121_-\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP048431.1\|WP_000531320.1\|795581_795914_-\|putative-DNA-binding-protein	unknown	unknown	gnl\|CDD\|234647
NZ_CP048431.1\|WP_000110251.1\|784280_785189_-\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NZ_CP048431.1\|WP_000007683.1\|795900_797151_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NZ_CP048431.1\|WP_000863479.1\|794188_795556_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NZ_CP048431.1\|WP_024273568.1\|797150_800717_-\|chromosome-segregation-protein-SMC	unknown	unknown	gnl\|CDD\|224117
NZ_CP048431.1\|WP_000195254.1\|779372_780680_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NZ_CP048431.1\|WP_001015597.1\|778059_778956_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|274042
NZ_CP048431.1\|WP_001261981.1\|792787_793291_-\|ribosome-maturation-factor-RimM	unknown	unknown	gnl\|CDD\|234650
NZ_CP048431.1\|WP_000931873.1\|783084_783957_-\|DNA-protecting-protein-DprA	unknown	unknown	gnl\|CDD\|223829
NZ_CP048431.1\|WP_000072681.1\|777517_778063_-\|ATP-dependent-protease-subunit-HslV	unknown	unknown	gnl\|CDD\|235477
NZ_CP048431.1\|WP_000181404.1\|791597_791948_-\|50S-ribosomal-protein-L19	unknown	unknown	gnl\|CDD\|235418
NZ_CP048431.1\|WP_070047601.1\|788521_791128_+\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|226888
NZ_CP048431.1\|WP_000268754.1\|793478_793754_-\|30S-ribosomal-protein-S16	unknown	unknown	gnl\|CDD\|223306
NZ_CP048431.1\|WP_000426914.1\|801710_801944_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197
NZ_CP048431.1\|WP_000176409.1\|786485_787253_-\|ribonuclease-HII	unknown	unknown	gnl\|CDD\|260003

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_001557331.1\|780835_782911_-\|type-I-DNA-topoisomerase	gnl\|CDD\|235516	PRK05582, PRK05582, type I DNA topoisomerase.	0
NZ_CP048431.1\|WP_164025908.1\|785210_786377_-\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NZ_CP048431.1\|WP_000687328.1\|792050_792788_-\|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl\|CDD\|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.98496e-164
NZ_CP048431.1\|WP_000043237.1\|800863_801595_-\|ribonuclease-III	gnl\|CDD\|234633	PRK00102, rnc, ribonuclease III; Reviewed.	4.78039e-115
NZ_CP048431.1\|WP_000236722.1\|787236_788121_-\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	1.29024e-158
NZ_CP048431.1\|WP_000531320.1\|795581_795914_-\|putative-DNA-binding-protein	gnl\|CDD\|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	5.84113e-47
NZ_CP048431.1\|WP_000110251.1\|784280_785189_-\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NZ_CP048431.1\|WP_000007683.1\|795900_797151_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	0
NZ_CP048431.1\|WP_000863479.1\|794188_795556_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NZ_CP048431.1\|WP_024273568.1\|797150_800717_-\|chromosome-segregation-protein-SMC	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0
NZ_CP048431.1\|WP_000195254.1\|779372_780680_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NZ_CP048431.1\|WP_001015597.1\|778059_778956_-\|tyrosine-recombinase-XerC	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	6.27893e-141
NZ_CP048431.1\|WP_001261981.1\|792787_793291_-\|ribosome-maturation-factor-RimM	gnl\|CDD\|234650	PRK00122, rimM, 16S rRNA-processing protein RimM; Provisional.	1.71152e-68
NZ_CP048431.1\|WP_000931873.1\|783084_783957_-\|DNA-protecting-protein-DprA	gnl\|CDD\|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	1.04761e-89
NZ_CP048431.1\|WP_000072681.1\|777517_778063_-\|ATP-dependent-protease-subunit-HslV	gnl\|CDD\|235477	PRK05456, PRK05456, ATP-dependent protease subunit HslV.	1.5909e-118
NZ_CP048431.1\|WP_000181404.1\|791597_791948_-\|50S-ribosomal-protein-L19	gnl\|CDD\|235418	PRK05338, rplS, 50S ribosomal protein L19; Provisional.	6.77895e-70
NZ_CP048431.1\|WP_070047601.1\|788521_791128_+\|YfhO-family-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NZ_CP048431.1\|WP_000268754.1\|793478_793754_-\|30S-ribosomal-protein-S16	gnl\|CDD\|223306	COG0228, RpsP, Ribosomal protein S16 [Translation, ribosomal structure and biogenesis].	3.01687e-41
NZ_CP048431.1\|WP_000426914.1\|801710_801944_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	5.23888e-31
NZ_CP048431.1\|WP_000176409.1\|786485_787253_-\|ribonuclease-HII	gnl\|CDD\|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	8.9948e-95

>NZ_CP048431.1|WP_070047601.1|788521_791128_+|YfhO-family-protein
MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSGAGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIKIGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGMSTVVIYFNFTWSFYGNLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQAIIIGCYYLYRLIFTYKYDIVSRTQKFICVISATVLSVLSSVFGLFTGISAFLENDRKQNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWILFIGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSIIALLYVLLSPTHPLALIVGIILLMVLAVILKFSLWRYKKLTVAILVLIVMIQQIVILDNNKNMAIKPYQQSISTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFIYHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRVNHDDNLPYGFKINSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAMLQGIVSNNTKDVNTHFKANKNLLSDSTIKLNSAAWQSPTKHLLQVKQNNGGLTVQLPKSVSNQFKDLYFEMDLELLSPDKAHDVKVNEYTQERNKLTYKYRRFVTPVTIRIKASDRIRLSLPKGKYRVNLKGIYGEDYTTLKDASNSLESVKVSKTKQGYTITKNKNSSGYIVLPTAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYTPPYYYLLITITIFGIICIIIFTRWARQK
>NZ_CP048431.1|WP_000236722.1|787236_788121_-|ribosome-biogenesis-GTPase-YlqF
MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMIDEVINQKPRVVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIKATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQWIKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQNDLARLKSHYNIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNYCFDIFKDMTEELANDANN
>NZ_CP048431.1|WP_000176409.1|786485_787253_-|ribonuclease-HII
MTLTIKEVTQLINAVNTIEELENHECFLDERKGVRNAIARRRKALEKEQALKEKYVEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNYLGLDDSKKVPFTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGLSVQPTHLLIDAMTLDNALPQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEYGFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL
>NZ_CP048431.1|WP_164025908.1|785210_786377_-|ADP-forming-succinate--CoA-ligase-subunit-beta
MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILQDSGLAIEPAATMAEGAQKIVKLVKEA
>NZ_CP048431.1|WP_000110251.1|784280_785189_-|succinate--CoA-ligase-subunit-alpha
MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKGGQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPVLDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEAAEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAATPSEIGSTLIEAAKEAGIYEALLTVNK
>NZ_CP048431.1|WP_000931873.1|783084_783957_-|DNA-protecting-protein-DprA
MLNHILLKLIWSRFTTAQIHLLLKTFPSCCEVDEYERMHILENFCKLLADKKIDAKVNRYKEISVDEIETTIQKTQLNYITCFDHNYPYLLKETYNYPIILFYKGNINLLSYPHTLAVVGSRLSGDYTLKALNHLFVSFQQMSFCVVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTSALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
>NZ_CP048431.1|WP_001557331.1|780835_782911_-|type-I-DNA-topoisomerase
MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK
>NZ_CP048431.1|WP_000195254.1|779372_780680_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
>NZ_CP048431.1|WP_001015597.1|778059_778956_-|tyrosine-recombinase-XerC
MNHIQDAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLELNTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKKEKYLPQFFYEEEMEALFKTVEEDTSKNLRDRVILELLYATGIRVSELVNIKKQDIDFYANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGVRYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHVSNQQLRKVYLNAHPRAKKENET
>NZ_CP048431.1|WP_000072681.1|777517_778063_-|ATP-dependent-protease-subunit-HslV
MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
>NZ_CP048431.1|WP_000181404.1|791597_791948_-|50S-ribosomal-protein-L19
MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR
>NZ_CP048431.1|WP_000687328.1|792050_792788_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
>NZ_CP048431.1|WP_001261981.1|792787_793291_-|ribosome-maturation-factor-RimM
MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNNDLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDIIGCTVFDDQEAPIGRVINIFETGANDVWVIKGSKEYLIPYIAEVVKEVDVENKKIIITPMEGLLD
>NZ_CP048431.1|WP_000268754.1|793478_793754_-|30S-ribosomal-protein-S16
MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
>NZ_CP048431.1|WP_000863479.1|794188_795556_-|signal-recognition-particle-protein
MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADVNFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTQLMGGENTSINMSNKPPTVVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPVYSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEIMLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGMSEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDFLEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPDTLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKGMNLPF
>NZ_CP048431.1|WP_000531320.1|795581_795914_-|putative-DNA-binding-protein
MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
>NZ_CP048431.1|WP_000007683.1|795900_797151_-|signal-recognition-particle-docking-protein-FtsY
MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDANDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNEEITTVENDQIVTEEKDDNHGSK
>NZ_CP048431.1|WP_024273568.1|797150_800717_-|chromosome-segregation-protein-SMC
MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDAIKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVTRRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQIIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVDPLKEEAAIAKEYKTLSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGKRHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLENISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSGEAHDEKLEEIKNEYYTLMSEQSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKDLSAVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGVKHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFLKERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLGNTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTTMRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRFTTQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLSKEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIAFFNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCHQDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKKVKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVTERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLLSGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVITHRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ
>NZ_CP048431.1|WP_000043237.1|800863_801595_-|ribonuclease-III
MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFINDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIFANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFPHVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAEGKGKTKKESEQRAAESAYKQLKQIK
>NZ_CP048431.1|WP_000426914.1|801710_801944_-|acyl-carrier-protein
MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP048431_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_3

875141-875327

Orphan

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCC	CRT

3 spacers

The CRISPR arrays of NZ_CP048431_3

>merge|NZ_CP048431|3|875141-875327|CRT
TCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCACTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCTTCTGTGTTGGGGCCCACCCCAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTCTCTATGTTGGGGCCCCGCC

>NZ_CP048431|3|1|875141-875327|CRT
TCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTC
ACTATGTTGGGGCCCCGCC	AACTTGCACATTATTGTAAGCTGACTTTTCGTCAGCT
TCTGTGTTGGGGCCCACCC	CAACTTGCATTGTCTGTAGAATTTCTTTTTGAAATTC
TCTATGTTGGGGCCCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000231632.1\|877918_878152_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000041896.1\|874209_874926_+\|superantigen-like-protein-SSL12	unknown	unknown	gnl\|CDD\|171995
NZ_CP048431.1\|WP_000857485.1\|876482_877442_+\|beta-channel-forming-cytolysin	unknown	unknown	gnl\|CDD\|273388
NZ_CP048431.1\|WP_000791581.1\|880111_880609_-\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_CP048431.1\|WP_001245802.1\|866210_866399_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_CP048431.1\|WP_001032816.1\|878773_878959_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001239285.1\|866647_867595_+\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_CP048431.1\|WP_000600047.1\|868434_869925_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_CP048431.1\|WP_000398672.1\|865164_865299_-\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_CP048431.1\|WP_000584398.1\|880867_881374_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001063559.1\|873376_874102_+\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_CP048431.1\|WP_000149429.1\|867899_868127_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000739208.1\|882815_883145_-\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007
NZ_CP048431.1\|WP_001074342.1\|870162_871095_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_CP048431.1\|WP_031917134.1\|871117_872119_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_CP048431.1\|WP_000765708.1\|875663_875810_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000739523.1\|872556_873282_+\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_CP048431.1\|WP_001802045.1\|875482_875707_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000739570.1\|882044_882446_+\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_CP048431.1\|WP_000669528.1\|879610_879961_-\|complement-inhibitor-SCIN-family-protein	unknown	unknown	gnl\|CDD\|371594

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000041896.1\|874209_874926_+\|superantigen-like-protein-SSL12	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	1.29441e-152
NZ_CP048431.1\|WP_000791581.1\|880111_880609_-\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.84801e-27
NZ_CP048431.1\|WP_001245802.1\|866210_866399_-\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_CP048431.1\|WP_000669528.1\|879610_879961_-\|complement-inhibitor-SCIN-family-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	8.46865e-41
NZ_CP048431.1\|WP_000857485.1\|876482_877442_+\|beta-channel-forming-cytolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.4958e-141
NZ_CP048431.1\|WP_001239285.1\|866647_867595_+\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84
NZ_CP048431.1\|WP_000398672.1\|865164_865299_-\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_CP048431.1\|WP_001063559.1\|873376_874102_+\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_CP048431.1\|WP_000739208.1\|882815_883145_-\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.51827e-21
NZ_CP048431.1\|WP_001074342.1\|870162_871095_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_CP048431.1\|WP_031917134.1\|871117_872119_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_CP048431.1\|WP_000600047.1\|868434_869925_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_CP048431.1\|WP_000739523.1\|872556_873282_+\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_CP048431.1\|WP_000739570.1\|882044_882446_+\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	5.2726e-76

>NZ_CP048431.1|WP_000041896.1|874209_874926_+|superantigen-like-protein-SSL12
MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>NZ_CP048431.1|WP_001063559.1|873376_874102_+|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_CP048431.1|WP_000739523.1|872556_873282_+|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_CP048431.1|WP_031917134.1|871117_872119_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILIADNIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_CP048431.1|WP_001074342.1|870162_871095_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_CP048431.1|WP_000600047.1|868434_869925_-|YfcC-family-protein
MILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_CP048431.1|WP_000149429.1|867899_868127_-|hypothetical-protein
MTHLTKVLVTLTGICVVLLFSKYFVAYANMVFDWNLRWYMLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_CP048431.1|WP_001239285.1|866647_867595_+|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_CP048431.1|WP_001245802.1|866210_866399_-|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_CP048431.1|WP_000398672.1|865164_865299_-|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_CP048431.1|WP_001802045.1|875482_875707_-|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_CP048431.1|WP_000765708.1|875663_875810_-|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_CP048431.1|WP_000857485.1|876482_877442_+|beta-channel-forming-cytolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>NZ_CP048431.1|WP_000231632.1|877918_878152_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_CP048431.1|WP_001032816.1|878773_878959_+|hypothetical-protein
MNKHINKKASKLLEDYKKVQQRKSEETDKGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_CP048431.1|WP_000669528.1|879610_879961_-|complement-inhibitor-SCIN-family-protein
MKFKKYILTGTLALLLSSTAIATIEGNKADASSKKDYIIQSEFHDKRIAEELKSLLDQSYVNDLAAGSLNPYYKRTIMMNQYRAKAALKSNNFAKMAEAKVALENIYKEIDEIINR
>NZ_CP048431.1|WP_000791581.1|880111_880609_-|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR
>NZ_CP048431.1|WP_000584398.1|880867_881374_-|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_CP048431.1|WP_000739570.1|882044_882446_+|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLSTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSIYWD
>NZ_CP048431.1|WP_000739208.1|882815_883145_-|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNAETVKKYNEYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK

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Crispr_ID: NZ_CP048431_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_4

1144352-1144433

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_4

>merge|NZ_CP048431|4|1144352-1144433|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCTCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP048431|4|3|1144352-1144433|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCTCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000422908.1\|1147101_1147641_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP048431.1\|WP_000255553.1\|1150057_1150675_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP048431.1\|WP_000662306.1\|1145416_1145530_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026002.1\|1138572_1139424_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP048431.1\|WP_001018962.1\|1143296_1143683_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP048431.1\|WP_164026000.1\|1136077_1137385_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP048431.1\|WP_001006453.1\|1134721_1135972_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP048431.1\|WP_000752917.1\|1139657_1139852_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP048431.1\|WP_001190695.1\|1146631_1146952_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP048431.1\|WP_000974460.1\|1148587_1149010_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP048431.1\|WP_000569884.1\|1149408_1149903_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP048431.1\|WP_000571218.1\|1141732_1142758_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP048431.1\|WP_000932212.1\|1144536_1145415_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP048431.1\|WP_001065801.1\|1143007_1143304_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP048431.1\|WP_000290490.1\|1145593_1145974_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP048431.1\|WP_000150013.1\|1147723_1148440_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP048431.1\|WP_000732326.1\|1140205_1141027_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NZ_CP048431.1\|WP_000589549.1\|1146131_1146488_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP048431.1\|WP_000168845.1\|1137483_1138245_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP048431.1\|WP_000520233.1\|1141044_1141740_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000422908.1\|1147101_1147641_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP048431.1\|WP_000255553.1\|1150057_1150675_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.40612e-61
NZ_CP048431.1\|WP_164026002.1\|1138572_1139424_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	1.74228e-75
NZ_CP048431.1\|WP_001018962.1\|1143296_1143683_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP048431.1\|WP_164026000.1\|1136077_1137385_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	2.53524e-135
NZ_CP048431.1\|WP_001006453.1\|1134721_1135972_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP048431.1\|WP_000752917.1\|1139657_1139852_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP048431.1\|WP_001190695.1\|1146631_1146952_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_CP048431.1\|WP_000974460.1\|1148587_1149010_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP048431.1\|WP_000569884.1\|1149408_1149903_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_CP048431.1\|WP_000571218.1\|1141732_1142758_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_CP048431.1\|WP_000932212.1\|1144536_1145415_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.72543e-74
NZ_CP048431.1\|WP_001065801.1\|1143007_1143304_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP048431.1\|WP_000290490.1\|1145593_1145974_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.28962e-69
NZ_CP048431.1\|WP_000150013.1\|1147723_1148440_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	5.95463e-148
NZ_CP048431.1\|WP_000732326.1\|1140205_1141027_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NZ_CP048431.1\|WP_000589549.1\|1146131_1146488_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP048431.1\|WP_000168845.1\|1137483_1138245_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP048431.1\|WP_000520233.1\|1141044_1141740_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100

>NZ_CP048431.1|WP_001018962.1|1143296_1143683_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP048431.1|WP_001065801.1|1143007_1143304_-|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP048431.1|WP_000571218.1|1141732_1142758_-|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP048431.1|WP_000520233.1|1141044_1141740_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP048431.1|WP_000732326.1|1140205_1141027_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP048431.1|WP_000752917.1|1139657_1139852_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP048431.1|WP_164026002.1|1138572_1139424_+|DUF368-domain-containing-protein
MQQFKWINILKGFAIGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP048431.1|WP_000168845.1|1137483_1138245_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP048431.1|WP_164026000.1|1136077_1137385_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGNANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP048431.1|WP_001006453.1|1134721_1135972_-|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NZ_CP048431.1|WP_000932212.1|1144536_1145415_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQEHLKSLDADNEDIPFSGAFSIKFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP048431.1|WP_000662306.1|1145416_1145530_-|hypothetical-protein
MKENLLGTIIWSIATFYYSRMMKIMNLAILKIKIGGS
>NZ_CP048431.1|WP_000290490.1|1145593_1145974_-|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSKMIGE
>NZ_CP048431.1|WP_000589549.1|1146131_1146488_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP048431.1|WP_001190695.1|1146631_1146952_+|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP048431.1|WP_000422908.1|1147101_1147641_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP048431.1|WP_000150013.1|1147723_1148440_-|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP048431.1|WP_000974460.1|1148587_1149010_+|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP048431.1|WP_000569884.1|1149408_1149903_+|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_CP048431.1|WP_000255553.1|1150057_1150675_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLIF

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Crispr_ID: NZ_CP048431_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_5

1188784-1188866

Unclear

Consensus_repeat	Method
AATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_5

>merge|NZ_CP048431|5|1188784-1188866|CRISPRCasFinder
AATTTCTACAGACAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAATTTCGAAAAGAATTTCTACAGACAATGCAAGTTGG

>NZ_CP048431|5|4|1188784-1188866|CRISPRCasFinder
AATTTCTACAGACAATGCAAGTTGG	GGTGTGGGCCCCAACACAGAGAATTTCGAAAAG
AATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000816304.1\|1183254_1184157_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP048431.1\|WP_000958224.1\|1193070_1194003_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP048431.1\|WP_000654030.1\|1180205_1181219_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
NZ_CP048431.1\|WP_000279414.1\|1179142_1180153_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
NZ_CP048431.1\|WP_000057543.1\|1190285_1191725_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP048431.1\|WP_000369722.1\|1187606_1188518_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP048431.1\|WP_000638419.1\|1199730_1199967_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP048431.1\|WP_000134963.1\|1189283_1190219_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP048431.1\|WP_001248939.1\|1186614_1187610_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP048431.1\|WP_000538141.1\|1199963_1200614_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP048431.1\|WP_001049165.1\|1184399_1184987_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP048431.1\|WP_000070831.1\|1181922_1182552_-\|DUF4887-domain-containing-protein	unknown	unknown	gnl\|CDD\|234750
NZ_CP048431.1\|WP_000749383.1\|1200787_1201627_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP048431.1\|WP_001260101.1\|1176930_1177692_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
NZ_CP048431.1\|WP_000513312.1\|1192225_1193065_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP048431.1\|WP_000662681.1\|1194622_1197469_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP048431.1\|WP_164026008.1\|1191732_1192218_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP048431.1\|WP_000006551.1\|1185559_1186504_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP048431.1\|WP_000229236.1\|1197476_1199462_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP048431.1\|WP_164026006.1\|1177813_1179004_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000816304.1\|1183254_1184157_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NZ_CP048431.1\|WP_000958224.1\|1193070_1194003_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP048431.1\|WP_000654030.1\|1180205_1181219_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.39665e-92
NZ_CP048431.1\|WP_000279414.1\|1179142_1180153_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
NZ_CP048431.1\|WP_000057543.1\|1190285_1191725_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP048431.1\|WP_000369722.1\|1187606_1188518_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP048431.1\|WP_000638419.1\|1199730_1199967_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP048431.1\|WP_000134963.1\|1189283_1190219_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP048431.1\|WP_001248939.1\|1186614_1187610_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP048431.1\|WP_000538141.1\|1199963_1200614_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP048431.1\|WP_001049165.1\|1184399_1184987_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NZ_CP048431.1\|WP_000070831.1\|1181922_1182552_-\|DUF4887-domain-containing-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	5.80381e-05
NZ_CP048431.1\|WP_000749383.1\|1200787_1201627_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NZ_CP048431.1\|WP_001260101.1\|1176930_1177692_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	2.48635e-146
NZ_CP048431.1\|WP_000513312.1\|1192225_1193065_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NZ_CP048431.1\|WP_000662681.1\|1194622_1197469_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP048431.1\|WP_164026008.1\|1191732_1192218_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	2.97282e-29
NZ_CP048431.1\|WP_000006551.1\|1185559_1186504_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP048431.1\|WP_000229236.1\|1197476_1199462_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP048431.1\|WP_164026006.1\|1177813_1179004_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0

>NZ_CP048431.1|WP_000369722.1|1187606_1188518_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP048431.1|WP_001248939.1|1186614_1187610_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP048431.1|WP_000006551.1|1185559_1186504_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP048431.1|WP_001049165.1|1184399_1184987_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP048431.1|WP_000816304.1|1183254_1184157_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP048431.1|WP_000070831.1|1181922_1182552_-|DUF4887-domain-containing-protein
MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFAYVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQQNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDNASQDKSDDNQKKTDDNKQPAQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK
>NZ_CP048431.1|WP_000654030.1|1180205_1181219_-|sugar-binding-transcriptional-regulator
MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHMDMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIKNKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAIHLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLLEPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQGQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKIILE
>NZ_CP048431.1|WP_000279414.1|1179142_1180153_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK
>NZ_CP048431.1|WP_164026006.1|1177813_1179004_-|phosphoglycerate-kinase
MAKKIVSDLNLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKILLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
>NZ_CP048431.1|WP_001260101.1|1176930_1177692_-|triose-phosphate-isomerase
MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTVVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSENQLKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK
>NZ_CP048431.1|WP_000134963.1|1189283_1190219_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP048431.1|WP_000057543.1|1190285_1191725_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP048431.1|WP_164026008.1|1191732_1192218_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDDVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP048431.1|WP_000513312.1|1192225_1193065_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP048431.1|WP_000958224.1|1193070_1194003_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP048431.1|WP_000662681.1|1194622_1197469_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP048431.1|WP_000229236.1|1197476_1199462_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP048431.1|WP_000638419.1|1199730_1199967_-|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP048431.1|WP_000538141.1|1199963_1200614_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP048431.1|WP_000749383.1|1200787_1201627_-|CHAP-domain-containing-protein
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH

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Crispr_ID: NZ_CP048431_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_6

1351553-1351646

Orphan

Consensus_repeat	Method
GGCTTTTATGCAGTTGCTGCACAAACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_6

>merge|NZ_CP048431|6|1351553-1351646|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAACTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGGGGCTCTTATGCAGTTGCTGCACAAACAA

>NZ_CP048431|6|5|1351553-1351646|CRISPRCasFinder
GGCTTTTATGCAGTTGCTGCACAAACAA	CTGTATTCCTTTACTCCCCTTGAGCTTTAGCGATTAGG
GGCTCTTATGCAGTTGCTGCACAAACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_001813976.1\|1350557_1351385_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NZ_CP048431.1\|WP_000365354.1\|1348685_1349405_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943
NZ_CP048431.1\|WP_001788287.1\|1356587_1357109_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378039
NZ_CP048431.1\|WP_001222133.1\|1346381_1347098_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026052.1\|1347259_1347766_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001200748.1\|1355078_1356089_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NZ_CP048431.1\|WP_000036088.1\|1342285_1342489_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001808006.1\|1342923_1343853_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NZ_CP048431.1\|WP_001819741.1\|1354387_1354771_-\|DUF1934-family-protein	unknown	unknown	gnl\|CDD\|226896
NZ_CP048431.1\|WP_000362967.1\|1347901_1348702_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP048431.1\|WP_000808902.1\|1359863_1360802_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP048431.1\|WP_001790232.1\|1349459_1350410_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NZ_CP048431.1\|WP_000901764.1\|1351761_1352397_-\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NZ_CP048431.1\|WP_001021145.1\|1352729_1354391_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NZ_CP048431.1\|WP_000180230.1\|1357136_1358432_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NZ_CP048431.1\|WP_000655099.1\|1354896_1355004_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026050.1\|1342505_1342730_+\|DUF2922-family-protein	unknown	unknown	gnl\|CDD\|378571
NZ_CP048431.1\|WP_001018677.1\|1344800_1345175_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NZ_CP048431.1\|WP_104011119.1\|1358471_1358948_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP048431.1\|WP_000633782.1\|1359116_1359653_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_001813976.1\|1350557_1351385_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	1.32108e-72
NZ_CP048431.1\|WP_000365354.1\|1348685_1349405_-\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38
NZ_CP048431.1\|WP_001788287.1\|1356587_1357109_-\|hypothetical-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NZ_CP048431.1\|WP_000633782.1\|1359116_1359653_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NZ_CP048431.1\|WP_001200748.1\|1355078_1356089_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NZ_CP048431.1\|WP_001819741.1\|1354387_1354771_-\|DUF1934-family-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	9.50091e-54
NZ_CP048431.1\|WP_001808006.1\|1342923_1343853_+\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	8.35021e-36
NZ_CP048431.1\|WP_000362967.1\|1347901_1348702_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	7.17592e-26
NZ_CP048431.1\|WP_000808902.1\|1359863_1360802_-\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NZ_CP048431.1\|WP_001790232.1\|1349459_1350410_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	5.19191e-48
NZ_CP048431.1\|WP_000901764.1\|1351761_1352397_-\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	3.98158e-90
NZ_CP048431.1\|WP_001021145.1\|1352729_1354391_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NZ_CP048431.1\|WP_000180230.1\|1357136_1358432_-\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NZ_CP048431.1\|WP_104011119.1\|1358471_1358948_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.53661e-11
NZ_CP048431.1\|WP_164026050.1\|1342505_1342730_+\|DUF2922-family-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	2.74487e-13
NZ_CP048431.1\|WP_001018677.1\|1344800_1345175_+\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26

>NZ_CP048431.1|WP_001813976.1|1350557_1351385_-|ABC-transporter-substrate-binding-protein
MKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NZ_CP048431.1|WP_001790232.1|1349459_1350410_-|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVTGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NZ_CP048431.1|WP_000365354.1|1348685_1349405_-|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NZ_CP048431.1|WP_000362967.1|1347901_1348702_-|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTAAFINKHHDEKHV
>NZ_CP048431.1|WP_164026052.1|1347259_1347766_-|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGKSIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NZ_CP048431.1|WP_001222133.1|1346381_1347098_-|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NZ_CP048431.1|WP_001018677.1|1344800_1345175_+|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NZ_CP048431.1|WP_001808006.1|1342923_1343853_+|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPKVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTLGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSIALLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NZ_CP048431.1|WP_164026050.1|1342505_1342730_+|DUF2922-family-protein
MTKTLELSFKSSLDKPVKLQLSQLNNVVTEQVVRDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK
>NZ_CP048431.1|WP_000036088.1|1342285_1342489_+|hypothetical-protein
MSKINHITIVLSFTKVDANGKQTEFKRRFANINPDASNDQIKTFSKLIERLTGETYSNIELIKSLSI
>NZ_CP048431.1|WP_000901764.1|1351761_1352397_-|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NZ_CP048431.1|WP_001021145.1|1352729_1354391_-|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NZ_CP048431.1|WP_001819741.1|1354387_1354771_-|DUF1934-family-protein
MLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NZ_CP048431.1|WP_000655099.1|1354896_1355004_-|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NZ_CP048431.1|WP_001200748.1|1355078_1356089_-|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NZ_CP048431.1|WP_001788287.1|1356587_1357109_-|hypothetical-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NZ_CP048431.1|WP_000180230.1|1357136_1358432_-|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NZ_CP048431.1|WP_104011119.1|1358471_1358948_-|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEYKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NZ_CP048431.1|WP_000633782.1|1359116_1359653_-|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NZ_CP048431.1|WP_000808902.1|1359863_1360802_-|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED

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Crispr_ID: NZ_CP048431_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_7

2137191-2137272

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_7

>merge|NZ_CP048431|7|2137191-2137272|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_CP048431|7|6|2137191-2137272|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000651837.1\|2135870_2136692_+\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_CP048431.1\|WP_164026228.1\|2132218_2133049_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP048431.1\|WP_164026234.1\|2145427_2146195_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP048431.1\|WP_001795496.1\|2146369_2146858_+\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_CP048431.1\|WP_001224182.1\|2134862_2135420_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP048431.1\|WP_001795157.1\|2137939_2138440_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000706519.1\|2131181_2132072_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_CP048431.1\|WP_000751267.1\|2141279_2141981_+\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_CP048431.1\|WP_001163740.1\|2128644_2129751_+\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379355
NZ_CP048431.1\|WP_001791985.1\|2139361_2139490_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000200684.1\|2139616_2140672_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP048431.1\|WP_000616225.1\|2136708_2137086_+\|glyoxalase	unknown	unknown	gnl\|CDD\|226134
NZ_CP048431.1\|WP_164026231.1\|2133068_2134079_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|225070
NZ_CP048431.1\|WP_000379821.1\|2143255_2145067_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP048431.1\|WP_000895193.1\|2129744_2131085_+\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NZ_CP048431.1\|WP_000161829.1\|2134165_2134870_-\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_CP048431.1\|WP_000996736.1\|2142256_2142745_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_CP048431.1\|WP_000055859.1\|2135551_2135851_+\|DUF2316-family-protein	unknown	unknown	gnl\|CDD\|226806
NZ_CP048431.1\|WP_164026499.1\|2138637_2139207_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP048431.1\|WP_000697134.1\|2137489_2137720_-\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000651837.1\|2135870_2136692_+\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.56436e-84
NZ_CP048431.1\|WP_164026228.1\|2132218_2133049_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.6708e-18
NZ_CP048431.1\|WP_164026234.1\|2145427_2146195_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.165e-31
NZ_CP048431.1\|WP_001224182.1\|2134862_2135420_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.50396e-13
NZ_CP048431.1\|WP_000379821.1\|2143255_2145067_+\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84
NZ_CP048431.1\|WP_000706519.1\|2131181_2132072_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.17569e-76
NZ_CP048431.1\|WP_000751267.1\|2141279_2141981_+\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	3.60255e-06
NZ_CP048431.1\|WP_001163740.1\|2128644_2129751_+\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	4.45347e-126
NZ_CP048431.1\|WP_000996736.1\|2142256_2142745_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.6785e-11
NZ_CP048431.1\|WP_000200684.1\|2139616_2140672_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
NZ_CP048431.1\|WP_000616225.1\|2136708_2137086_+\|glyoxalase	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.45544e-58
NZ_CP048431.1\|WP_164026231.1\|2133068_2134079_-\|amidohydrolase-family-protein	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	1.8596e-78
NZ_CP048431.1\|WP_000895193.1\|2129744_2131085_+\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	1.90855e-93
NZ_CP048431.1\|WP_000161829.1\|2134165_2134870_-\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.08524e-67
NZ_CP048431.1\|WP_000055859.1\|2135551_2135851_+\|DUF2316-family-protein	gnl\|CDD\|226806	COG4367, COG4367, Uncharacterized protein conserved in bacteria [Function unknown].	1.06282e-39
NZ_CP048431.1\|WP_164026499.1\|2138637_2139207_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.42011e-08
NZ_CP048431.1\|WP_000697134.1\|2137489_2137720_-\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31

>NZ_CP048431.1|WP_000616225.1|2136708_2137086_+|glyoxalase
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGAVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>NZ_CP048431.1|WP_000651837.1|2135870_2136692_+|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDNVSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSGVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQNYNK
>NZ_CP048431.1|WP_000055859.1|2135551_2135851_+|DUF2316-family-protein
MSLNKEQRRITCEELQAHFEASTLSVQMIAEKLNVTTEDVEKVLAMTAPLGIFSHQLQRFIHLVWDVRDVINDNIKGNGQTPEPYTYLKGEKEDYWFLR
>NZ_CP048431.1|WP_001224182.1|2134862_2135420_-|TetR/AcrR-family-transcriptional-regulator
MRKDAIENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>NZ_CP048431.1|WP_000161829.1|2134165_2134870_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
>NZ_CP048431.1|WP_164026231.1|2133068_2134079_-|amidohydrolase-family-protein
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLGVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNIIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>NZ_CP048431.1|WP_164026228.1|2132218_2133049_-|alpha/beta-fold-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPIPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSNYWKDKNDDIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSKFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNLWG
>NZ_CP048431.1|WP_000706519.1|2131181_2132072_+|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHKSLHQMINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>NZ_CP048431.1|WP_000895193.1|2129744_2131085_+|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLTATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGLKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII
>NZ_CP048431.1|WP_001163740.1|2128644_2129751_+|NAD(P)-binding-domain-containing-protein
MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKHWPKSTLTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYELNIFENTVVTNISVDDAFYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDFDNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQRLGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVHTPHEPILATGFDATKNPIVQQLFVTTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLTQREGLPAKQEVIENYQKNQMYLDDYSCCEVSCTC
>NZ_CP048431.1|WP_000697134.1|2137489_2137720_-|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>NZ_CP048431.1|WP_001795157.1|2137939_2138440_-|hypothetical-protein
MTSIFVFAYLNNTSGNMLFRQQMICACLLANVRHSSIVCLNNICCIVDMRCLNTKIGGIDVSETDEPQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIARGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHTMSFDNAHFFAQLRHPVL
>NZ_CP048431.1|WP_164026499.1|2138637_2139207_-|TetR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCKLNSEAFCNKVHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>NZ_CP048431.1|WP_001791985.1|2139361_2139490_+|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>NZ_CP048431.1|WP_000200684.1|2139616_2140672_+|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>NZ_CP048431.1|WP_000751267.1|2141279_2141981_+|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>NZ_CP048431.1|WP_000996736.1|2142256_2142745_+|GNAT-family-N-acetyltransferase
MAINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNNGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDKGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKD
>NZ_CP048431.1|WP_000379821.1|2143255_2145067_+|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_CP048431.1|WP_164026234.1|2145427_2146195_+|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAVEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSSGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_CP048431.1|WP_001795496.1|2146369_2146858_+|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD

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Crispr_ID: NZ_CP048431_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_8

2219935-2220067

Orphan

Consensus_repeat	Method
ATTGAAGAAGATACAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP048431_8

>merge|NZ_CP048431|8|2219935-2220067|PILER-CR
ATTGAAGAAGATACAAACAAAGATAAACCAAATTATCAATTCGGTGGACACAACATTGTTGATTTTGAAGAAGATACACTTCCGAAAGTAAGCGGTCAAAATGAAGGTCAACAAACGATTGAAGAAGATACAA

>NZ_CP048431|8|1|2219935-2220067|PILER-CR
ATTGAAGAAGATACAA	ACAAAGATAAACCAAATTATCAATTCGGTGGACACAACATTGTTGAT
TTTGAAGAAGATACAC	TTCCGAAAGTAAGCGGTCAAAATGAAGGTCAACAAACG
ATTGAAGAAGATACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000966098.1\|2231563_2232757_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP048431.1\|WP_000876654.1\|2213950_2215504_+\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP048431.1\|WP_000386367.1\|2225338_2226082_-\|HTH-type-transcriptional-regulator-SarU	unknown	unknown	gnl\|CDD\|130944
NZ_CP048431.1\|WP_000660709.1\|2206676_2207954_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP048431.1\|WP_000998872.1\|2226405_2226762_+\|HTH-type-transcriptional-regulator-SarT	unknown	unknown	gnl\|CDD\|130944
NZ_CP048431.1\|WP_000289136.1\|2211471_2212164_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP048431.1\|WP_000481427.1\|2215620_2216979_+\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
NZ_CP048431.1\|WP_164026266.1\|2213246_2213927_+\|FCD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224715
NZ_CP048431.1\|WP_164026268.1\|2224261_2225128_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP048431.1\|WP_001621913.1\|2208147_2208351_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026272.1\|2236020_2236413_+\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239517
NZ_CP048431.1\|WP_001117050.1\|2210824_2211241_+\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|227213
NZ_CP048431.1\|WP_076079486.1\|2234080_2235889_-\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NZ_CP048431.1\|WP_000841437.1\|2221217_2224082_+\|fibronectin-binding-protein-FnbB	unknown	unknown	gnl\|CDD\|371043
NZ_CP048431.1\|WP_000678764.1\|2233530_2233797_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001834510.1\|2217010_2217313_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_001815353.1\|2208862_2210686_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP048431.1\|WP_000217722.1\|2233078_2233387_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_072361956.1\|2232767_2232971_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000074008.1\|2212328_2213093_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000966098.1\|2231563_2232757_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.77868e-57
NZ_CP048431.1\|WP_164026268.1\|2224261_2225128_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	8.50581e-176
NZ_CP048431.1\|WP_000386367.1\|2225338_2226082_-\|HTH-type-transcriptional-regulator-SarU	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	9.70785e-26
NZ_CP048431.1\|WP_000660709.1\|2206676_2207954_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.24287e-91
NZ_CP048431.1\|WP_000998872.1\|2226405_2226762_+\|HTH-type-transcriptional-regulator-SarT	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	4.06037e-28
NZ_CP048431.1\|WP_000289136.1\|2211471_2212164_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	8.50652e-86
NZ_CP048431.1\|WP_164026266.1\|2213246_2213927_+\|FCD-domain-containing-protein	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	5.18235e-43
NZ_CP048431.1\|WP_000876654.1\|2213950_2215504_+\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP048431.1\|WP_000481427.1\|2215620_2216979_+\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.5428e-168
NZ_CP048431.1\|WP_164026272.1\|2236020_2236413_+\|NUDIX-domain-containing-protein	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	3.61066e-56
NZ_CP048431.1\|WP_001117050.1\|2210824_2211241_+\|DUF2188-domain-containing-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	8.79024e-63
NZ_CP048431.1\|WP_000841437.1\|2221217_2224082_+\|fibronectin-binding-protein-FnbB	gnl\|CDD\|371043	pfam10425, SdrG_C_C, C-terminus of bacterial fibrinogen-binding adhesin. This is the C-terminal half of a bacterial fibrinogen-binding adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, pfam05738.	1.32148e-31
NZ_CP048431.1\|WP_001815353.1\|2208862_2210686_+\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	1.40393e-88
NZ_CP048431.1\|WP_076079486.1\|2234080_2235889_-\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP048431.1\|WP_000074008.1\|2212328_2213093_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	4.21397e-33

>NZ_CP048431.1|WP_001834510.1|2217010_2217313_+|hypothetical-protein
MQYIALKHVYFYAENRLKYSESERYKKYIGYFRVMKGVSRHVFVRIVQAIIMKRLVYCFKLDNDEFNLKNKYKKYKPCVTRVSDDLNTIYRYISNNKIIN
>NZ_CP048431.1|WP_000481427.1|2215620_2216979_+|gluconate-permease
MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVMFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>NZ_CP048431.1|WP_000876654.1|2213950_2215504_+|gluconokinase
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMLPELVPTTYVMKGMKECYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELLVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIKENVAVYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>NZ_CP048431.1|WP_164026266.1|2213246_2213927_+|FCD-domain-containing-protein
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLSFGEQEKKEMYDLRLMLESFAFSRVKNQDRLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNLQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>NZ_CP048431.1|WP_000074008.1|2212328_2213093_+|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLNKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIISAILMKNKWPFLIALPFMIGYGIGVTFYYQQKVAYLCPNCQHIFSPSLWQVIKAKHTATTRRFECPNCHETHYCIEVPKAHMSTEQLEISRIQHNN
>NZ_CP048431.1|WP_000289136.1|2211471_2212164_+|GTP-pyrophosphokinase-family-protein
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE
>NZ_CP048431.1|WP_001117050.1|2210824_2211241_+|DUF2188-domain-containing-protein
MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEKAEVDSEYATTDNEEHIQEQSNQDKSYFDSESIGNQSGGVRQREPLMDGPHPKVVESFKDV
>NZ_CP048431.1|WP_001815353.1|2208862_2210686_+|FUSC-family-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYNDKSAFLQVAKTAVDSFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDHIIAQLDNSEENVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFDFEKAYWIPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALFTEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIMIAIIGLFVLGQRTASALLPNVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQVYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAKHFELNTGLEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>NZ_CP048431.1|WP_001621913.1|2208147_2208351_+|hypothetical-protein
MKENLEKYIRSLPLIGLIISIFLIILYFLIYRVEGNFCVIILYCLLPLFVNTSLYILYVIIFRYFKK
>NZ_CP048431.1|WP_000660709.1|2206676_2207954_+|MFS-transporter
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNDFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK
>NZ_CP048431.1|WP_000841437.1|2221217_2224082_+|fibronectin-binding-protein-FnbB
MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTTVEESGSSATESKASETQTTTNNVNTIDETQSYSVTSTEQPSQSTQVTTEEAPTTVQAPKVETSRVDLPSEKVADKETTGTQVDTAQPSNFSEIKPRVKRSADVAVVAGEAKATGTDVTNKVTVENGSEIVGHKQDTNVVNPHNAERVTLKYKWKFGEGIKEGDYFDFTLSDNVETHGISTLRKVPEIKSTDGQVMAIGEVVEERKIRYTFKEYVKDKKDLTAELSLNLFIDPTTVTKQGKQKVEVTLGDKTIEKEFDIKYLDGVKDRMGVTVNGRIDTLNKEDGKFSHFAYIKPNNRSLSSVTVTGQVTSGHKQNANNPTVKVYKHIGSDELAESVYAKLDDASKFEDVTEKVNLSYTGEGGYSFTFDSLEDNNNYVVKYEGEYNTKAKDLNFQTRLTGYHNYYPYYPYYPVQLTWNNGVAFYSNNAQGDGKDKPKEPIIEHSTPIELEFKSEPPVEKHELTGTIEESNDSKPIDFEYHTAVEGAEGHAEGIIETEEDSIHVDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEDSTKGIVTGAVSDHTTVEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENYQHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIQGQNNGDQSFEEDTEEDKPKYEQGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGGHSSVDFEEDTLPQVSGHNEGQQTIEEDTTPPIVPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPEVPTPPTPEIPSEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNHKA
>NZ_CP048431.1|WP_164026268.1|2224261_2225128_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVTEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKELGL
>NZ_CP048431.1|WP_000386367.1|2225338_2226082_-|HTH-type-transcriptional-regulator-SarU
MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
>NZ_CP048431.1|WP_000998872.1|2226405_2226762_+|HTH-type-transcriptional-regulator-SarT
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
>NZ_CP048431.1|WP_000966098.1|2231563_2232757_+|MFS-transporter
MLYLEVLKNRNFTYLLIGNFLRRSCFVLFSLQIIWFTVELTNQSSLKLSMMVMSQTLPFIIFGIFGGAYSDKHNKKKILYLSDLILSLIIIIIPLLAITSNLNYLTLLTISTAITIINCYTDPAFRAILPEIIDEEHLATSNALIDSLQRGSNIILPALIGVIVILVGNVGVFFICSILLFLGFIFNALLKYTNNNMIDRHSKEDFSETWEFLKQSKEIPFIIIIQFACILINTGLWRVALPLFISNILKEGVGVYGLATSCLGIASLLMSLIMGLLSEKRLIFKFSIGVLVWGIGLSIINVFPSVAILYIGATLVGLGQSIEGLTRSVAIQIKTPNHLMGKVFSISSTSNYAADTLSLGLISLIIPLLSLSNIFISGGAIISMLSLSGLKFFKKSM
>NZ_CP048431.1|WP_072361956.1|2232767_2232971_+|hypothetical-protein
MLINAIKVGIEMKYKISLAYNLAIIIGSLIILCILISRGHDIYVILIPILTVLASLINLFCDIKKHK
>NZ_CP048431.1|WP_000217722.1|2233078_2233387_-|hypothetical-protein
MTVNIVVSIVFCISMVILGIYVAITKDFTLISYINQTAIADKHKNQIAYIFALCISLSAVFLMSSILCFEYDFIVLAFLFLTIALLLIALFYVCFYKITKYP
>NZ_CP048431.1|WP_000678764.1|2233530_2233797_-|hypothetical-protein
MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAHTLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD
>NZ_CP048431.1|WP_076079486.1|2234080_2235889_-|phospho-sugar-mutase
MHFHTQVLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNNPTIVIHYDIRHLSTEFAQIIANVLANNQITVYLPDTYKTTPELSFAVRSLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSITDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHANLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELKQIYQTVGRHEDTLFSHTLEGLEGKKKINAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS
>NZ_CP048431.1|WP_164026272.1|2236020_2236413_+|NUDIX-domain-containing-protein
MKKVINVVGAIIFSDNKILCAQRSEKMSLPLMWEFPGGKVEKNETEKDALIREIREEMKCDLIVGDKVISTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSIEWLSINELDKLNWAPADIPAVNKIMTEG

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Crispr_ID: NZ_CP048431_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP048431_9

2706420-2706509

Orphan

Consensus_repeat	Method
TGATTGAGAAGTCAGTCGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP048431_9

>merge|NZ_CP048431|9|2706420-2706509|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAACTATTGCAAAAGAAAAACGATTATGTATAATAAAATTATAAATTGATTGAGAAGTCAGTCAAAAACG

>NZ_CP048431|9|7|2706420-2706509|CRISPRCasFinder
TGATTGAGAAGTCAGTCGAAAAAC	TATTGCAAAAGAAAAACGATTATGTATAATAAAATTATAAAT
TGATTGAGAAGTCAGTCAAAAACG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048431.1\|WP_000567972.1\|2710699_2711044_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000620857.1\|2705678_2706353_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379188
NZ_CP048431.1\|WP_000708433.1\|2707062_2707218_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026416.1\|2708176_2710429_+\|DNA-primase	unknown	unknown	gnl\|CDD\|227316
NZ_CP048431.1\|WP_164026412.1\|2702447_2702732_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP048431.1\|WP_000522384.1\|2699422_2700049_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP048431.1\|WP_000240645.1\|2702807_2704424_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP048431.1\|WP_000867940.1\|2698276_2699062_-\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP048431.1\|WP_001231376.1\|2707202_2707406_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_000179345.1\|2704492_2705665_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP048431.1\|WP_000481967.1\|2706748_2707066_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP048431.1\|WP_164026409.1\|2696741_2697311_-\|accessory-gene-regulator-AgrB	unknown	unknown	gnl\|CDD\|214819
NZ_CP048431.1\|WP_000197635.1\|2701529_2702273_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP048431.1\|WP_001549197.1\|2697546_2697681_+\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP048431.1\|WP_162675796.1\|2707407_2707791_+\|pathogenicity-island-protein	unknown	unknown	unknown
NZ_CP048431.1\|WP_164026414.1\|2707791_2708106_+\|DUF1474-family-protein	unknown	unknown	gnl\|CDD\|369323
NZ_CP048431.1\|WP_164026410.1\|2700245_2701505_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768
NZ_CP048431.1\|WP_164026418.1\|2711045_2711687_+\|pathogenicity-island-protein	unknown	unknown	gnl\|CDD\|374630
NZ_CP048431.1\|WP_000153640.1\|2706525_2706744_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP048431.1\|WP_164026420.1\|2711985_2712327_+\|pathogenicity-island-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP048431.1\|WP_000620857.1\|2705678_2706353_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NZ_CP048431.1\|WP_164026416.1\|2708176_2710429_+\|DNA-primase	gnl\|CDD\|227316	COG4983, COG4983, Uncharacterized conserved protein [Function unknown].	1.25828e-33
NZ_CP048431.1\|WP_164026412.1\|2702447_2702732_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	1.91966e-44
NZ_CP048431.1\|WP_000522384.1\|2699422_2700049_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	5.71771e-116
NZ_CP048431.1\|WP_000240645.1\|2702807_2704424_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP048431.1\|WP_000867940.1\|2698276_2699062_-\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	7.8671e-127
NZ_CP048431.1\|WP_164026418.1\|2711045_2711687_+\|pathogenicity-island-protein	gnl\|CDD\|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	2.51163e-113
NZ_CP048431.1\|WP_000179345.1\|2704492_2705665_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.10093e-47
NZ_CP048431.1\|WP_000481967.1\|2706748_2707066_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NZ_CP048431.1\|WP_164026409.1\|2696741_2697311_-\|accessory-gene-regulator-AgrB	gnl\|CDD\|214819	smart00793, AgrB, Accessory gene regulator B. The accessory gene regulator (agr) of Staphylococcus aureus is the central regulatory system that controls the gene expression for a large set of virulence factors. The arg locus consists of two transcripts: RNAII and RNAIII. RNAII encodes four genes (agrA, B, C, and D) whose gene products assemble a quorum sensing system. At low cell density, the agr genes are continuously expressed at basal levels. A signal molecule, autoinducing peptide (AIP), produced and secreted by the bacteria, accumulates outside of the cells. When the cell density increases and the AIP concentration reaches a threshold, it activates the agr response, i.e. activation of secreted protein gene expression and subsequent repression of cell wall-associated protein genes. AgrB and AgrD are essential for the production of the autoinducing peptide which functions as a signal for quorum sensing. AgrB is a transmembrane protein. AgrB is involved in the proteolytic processing of AgrD and may have both proteolytic enzyme activity and a transporter facilitating the export of the processed AgrD peptide.	3.9397e-47
NZ_CP048431.1\|WP_000197635.1\|2701529_2702273_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NZ_CP048431.1\|WP_001549197.1\|2697546_2697681_+\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP048431.1\|WP_164026414.1\|2707791_2708106_+\|DUF1474-family-protein	gnl\|CDD\|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	3.29402e-20
NZ_CP048431.1\|WP_164026410.1\|2700245_2701505_+\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	1.6727e-10
NZ_CP048431.1\|WP_000153640.1\|2706525_2706744_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11

>NZ_CP048431.1|WP_000620857.1|2705678_2706353_-|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NZ_CP048431.1|WP_000179345.1|2704492_2705665_-|site-specific-integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKPIQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKKKISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKTDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NZ_CP048431.1|WP_000240645.1|2702807_2704424_+|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP048431.1|WP_164026412.1|2702447_2702732_+|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAIGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP048431.1|WP_000197635.1|2701529_2702273_-|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP048431.1|WP_164026410.1|2700245_2701505_+|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATYTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQYPSPNPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQHGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP048431.1|WP_000522384.1|2699422_2700049_-|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP048431.1|WP_000867940.1|2698276_2699062_-|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNEAQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP048431.1|WP_001549197.1|2697546_2697681_+|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP048431.1|WP_164026409.1|2696741_2697311_-|accessory-gene-regulator-AgrB
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESNILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK
>NZ_CP048431.1|WP_000153640.1|2706525_2706744_+|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NZ_CP048431.1|WP_000481967.1|2706748_2707066_+|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NZ_CP048431.1|WP_000708433.1|2707062_2707218_+|hypothetical-protein
MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGEITTCENK
>NZ_CP048431.1|WP_001231376.1|2707202_2707406_+|hypothetical-protein
MRKQVIITKTVVGWYNIKDTQHNLMLNIPPKVFEQYFPDVSKDVQVACLEMDLSKITEIKNKKKVGS
>NZ_CP048431.1|WP_162675796.1|2707407_2707791_+|pathogenicity-island-protein
MEIKQKYQLSKVVKILEVVLYEEDKSQSDKDYHYQDEAFYEYALKLVHNGLFNILAELDFEDEAFLILDEVTMTLSDVMKETQHVYRYSVIDEKGEHKHTTDRKGHVIGMLEWALDYIVGNIEVEVL
>NZ_CP048431.1|WP_164026414.1|2707791_2708106_+|DUF1474-family-protein
MNWEINDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAKNVKKA
>NZ_CP048431.1|WP_164026416.1|2708176_2710429_+|DNA-primase
MAIKEKDKILEVNSLEIPDELIELPQWVLWRAEWNEKQQQYSKIPYSYAGYKASSTNSDTWTIFDAINSIYEQNDRYDGIGFVISEHDNYIVLDIDNAIDESSQITSNLALDMTKMTYCEKSPSGTGLHCFFKGELPKERKKKRSDLDIELYDNARFMTMTGESIGQREISDDQSLLNNLVERYFKQEELPETFIGNNITNKSNLDDEDVINIMLKSKQKDKISNLLQGNYEPYFDSPSEAVQSLLHYLAFYTSKDKEQMERIFLNYNNLTDKWGSKRGNTTWGQLELDKAINNQSEVYVKPGKENPSKLIKKGSWWFYPNDDTNRKPKFNHTIMAKFICQEYHIVRYPDADSDIYIYNTQTGIYELDKTGRKLRKIIRSLDNLKDNSVKEVRNYIVDMCDVRSVVNNEYVAVKNGLVHYHTKIFRTFTPDIFVIDKLPTTYNPNAYGEFVDTTIQKVSCNHETTIMNIYEMFAQVLYPKILIDKIIYLLGTVADNGKSTVQHMIKATFDSGGRISSVSPQRLANNHFAGSSIYGKMANMVDDLPNIEIEDAGNIKTAITGGYLEIEQKGKASQSVRMQTPFIIASNHYPKFKESGEQINKRLHIIPFNYSFKDDQERLSVTESTNKIYNKSAKEYVLKLAIDTLADMLQRDGSYITPNERSDKSAELFSDNNNPLSEYLENRNIDFFLNNPGAETYKDYKVWCHSNFIRKPVNKDDFITLLENYYDIEWKRSVKYTENNVRWGFKKLKR
>NZ_CP048431.1|WP_000567972.1|2710699_2711044_+|hypothetical-protein
MIDVNQPEHFDELNEDKKCALMEFCNSLDKIKSFNTRHSSYGLKHVFEAEYREELENTFEGSYITNGQFKGAMLKAGFDVKNKTQLNWHFNLSERSIKNLGDSKIYKSIKGARI
>NZ_CP048431.1|WP_164026418.1|2711045_2711687_+|pathogenicity-island-protein
MNIEIIANQFETRAGTLLRYYTGLLEHSKVQPYCFKLYNYPFDMVYVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIISIEGHYVGYELHDGKQLSISDMMASQLFEDEYFMYGLETYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPARELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>NZ_CP048431.1|WP_164026420.1|2711985_2712327_+|pathogenicity-island-protein
MQIIAEKETYHLPTEHLQVFNVIKNTPNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIEV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1633726-1633754	0	1.0
NZ_CP048431_2	2.1\|791254\|32\|NZ_CP048431\|CRISPRCasFinder	791254-791285	32	NZ_CP048431.1	536758-536789	0	1.0
NZ_CP048431_2	2.1\|791254\|32\|NZ_CP048431\|CRISPRCasFinder	791254-791285	32	NZ_CP048431.1	581667-581698	0	1.0
NZ_CP048431_2	2.1\|791254\|32\|NZ_CP048431\|CRISPRCasFinder	791254-791285	32	NZ_CP048431.1	581725-581756	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	581830-581866	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	2022765-2022801	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	536650-536686	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	536706-536742	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	669290-669326	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	1235359-1235395	0	1.0
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	2425816-2425852	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	80153-80189	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	405315-405351	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	669348-669384	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	977714-977750	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	1181617-1181653	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	1633819-1633855	0	1.0
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	2425872-2425908	0	1.0
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	2460186-2460222	0	1.0
NZ_CP048431_5	5.1\|1188809\|33\|NZ_CP048431\|CRISPRCasFinder	1188809-1188841	33	NZ_CP048431.1	78791-78823	0	1.0
NZ_CP048431_5	5.1\|1188809\|33\|NZ_CP048431\|CRISPRCasFinder	1188809-1188841	33	NZ_CP048431.1	581694-581726	0	1.0
NZ_CP048431_7	7.1\|2137215\|34\|NZ_CP048431\|CRISPRCasFinder	2137215-2137248	34	NZ_CP048431.1	581813-581846	0	1.0
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	78798-78826	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	536785-536813	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	581643-581671	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	581701-581729	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	669427-669455	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	879261-879289	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1095267-1095295	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1144323-1144351	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1194250-1194278	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1633671-1633699	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1718177-1718205	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1841510-1841538	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	2137273-2137301	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	2425951-2425979	1	0.966
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	2460173-2460201	1	0.966
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	78752-78788	1	0.973
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	1188770-1188806	1	0.973
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	2022821-2022857	1	0.973
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	2187897-2187933	1	0.973
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	581772-581808	1	0.973
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	2187841-2187877	1	0.973
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	2460130-2460166	1	0.973
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	2270119-2270155	1	0.973
NZ_CP048431_4	4.1\|1144376\|34\|NZ_CP048431\|CRISPRCasFinder	1144376-1144409	34	NZ_CP048431.1	581813-581846	1	0.971
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	791223-791251	2	0.931
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	1718288-1718316	2	0.931
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	2187770-2187798	2	0.931
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP048431.1	2270140-2270168	2	0.931
NZ_CP048431_3	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	NZ_CP048431.1	283451-283487	2	0.946
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	875104-875140	2	0.946
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	1144010-1144046	2	0.946
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	1144066-1144102	2	0.946
NZ_CP048431_3	3.2\|875216\|37\|NZ_CP048431\|CRT	875216-875252	37	NZ_CP048431.1	2295442-2295478	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	69461-69497	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	1144336-1144372	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	1194263-1194299	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	879240-879276	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	1095246-1095282	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	1841489-1841525	2	0.946
NZ_CP048431_3	3.3\|875272\|37\|NZ_CP048431\|CRT	875272-875308	37	NZ_CP048431.1	2137252-2137288	2	0.946
NZ_CP048431_7	7.1\|2137215\|34\|NZ_CP048431\|CRISPRCasFinder	2137215-2137248	34	NZ_CP048431.1	669310-669343	2	0.941

1. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1633726-1633754, mismatch: 0, identity: 1.0

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctatgttggggc	Protospacer
*****************************

2. spacer 2.1|791254|32|NZ_CP048431|CRISPRCasFinder matches to position: 536758-536789, mismatch: 0, identity: 1.0

acaccccaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
********************************

3. spacer 2.1|791254|32|NZ_CP048431|CRISPRCasFinder matches to position: 581667-581698, mismatch: 0, identity: 1.0

acaccccaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
********************************

4. spacer 2.1|791254|32|NZ_CP048431|CRISPRCasFinder matches to position: 581725-581756, mismatch: 0, identity: 1.0

acaccccaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
********************************

5. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 581830-581866, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

6. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 2022765-2022801, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

7. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 536650-536686, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

8. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 536706-536742, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

9. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 669290-669326, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

10. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 1235359-1235395, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

11. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 2425816-2425852, mismatch: 0, identity: 1.0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

12. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 80153-80189, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

13. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 405315-405351, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

14. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 669348-669384, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

15. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 977714-977750, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

16. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 1181617-1181653, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

17. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 1633819-1633855, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

18. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 2425872-2425908, mismatch: 0, identity: 1.0

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcagct	Protospacer
*************************************

19. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 2460186-2460222, mismatch: 0, identity: 1.0

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttctttttgaaattc	Protospacer
*************************************

20. spacer 5.1|1188809|33|NZ_CP048431|CRISPRCasFinder matches to position: 78791-78823, mismatch: 0, identity: 1.0

ggtgtgggccccaacacagagaatttcgaaaag	CRISPR spacer
ggtgtgggccccaacacagagaatttcgaaaag	Protospacer
*********************************

21. spacer 5.1|1188809|33|NZ_CP048431|CRISPRCasFinder matches to position: 581694-581726, mismatch: 0, identity: 1.0

ggtgtgggccccaacacagagaatttcgaaaag	CRISPR spacer
ggtgtgggccccaacacagagaatttcgaaaag	Protospacer
*********************************

22. spacer 7.1|2137215|34|NZ_CP048431|CRISPRCasFinder matches to position: 581813-581846, mismatch: 0, identity: 1.0

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
**********************************

23. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 78798-78826, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

24. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 536785-536813, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

25. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 581643-581671, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

26. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 581701-581729, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

27. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 669427-669455, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

28. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 879261-879289, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

29. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1095267-1095295, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

30. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1144323-1144351, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

31. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1194250-1194278, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

32. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1633671-1633699, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctttgttggggc	Protospacer
******************* *********

33. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1718177-1718205, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

34. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1841510-1841538, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

35. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 2137273-2137301, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

36. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 2425951-2425979, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctctgtgttggggc	Protospacer
*******************.*********

37. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 2460173-2460201, mismatch: 1, identity: 0.966

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttctttttgaaattctctatgttggggc	Protospacer
********.********************

38. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 78752-78788, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtttgtagaaattgggaatccaatttc	Protospacer
************.************************

39. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 1188770-1188806, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattggaaatccaatttc	Protospacer
*************************.***********

40. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 2022821-2022857, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaatcgggaatccaatttc	Protospacer
**********************.**************

41. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 2187897-2187933, mismatch: 1, identity: 0.973

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttacattgtctgtagaaattgggaatccaatttc	Protospacer
*****.*******************************

42. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 581772-581808, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgacttttcgtcatct	Protospacer
********************************** **

43. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 2187841-2187877, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgatttttcgtcagct	Protospacer
************************.************

44. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 2460130-2460166, mismatch: 1, identity: 0.973

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtatgctgacttttcgtcagct	Protospacer
****************** ******************

45. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 2270119-2270155, mismatch: 1, identity: 0.973

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttacattgtctgtagaatttctttttgaaattc	Protospacer
******.******************************

46. spacer 4.1|1144376|34|NZ_CP048431|CRISPRCasFinder matches to position: 581813-581846, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

47. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 791223-791251, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcatttcgaaattctctgtgttggggc	Protospacer
**** **************.*********

48. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 1718288-1718316, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcttttcgaaattctttgtgttggggc	Protospacer
*****************.*.*********

49. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 2187770-2187798, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttcatttcgaaattctctgtgttggggc	Protospacer
**** **************.*********

50. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to position: 2270140-2270168, mismatch: 2, identity: 0.931

tttcttttcgaaattctctatgttggggc	CRISPR spacer
tttctttttgaaattctctgtgttggggc	Protospacer
********.**********.*********

51. spacer 3.1|875160|37|NZ_CP048431|CRT matches to position: 283451-283487, mismatch: 2, identity: 0.946

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggggtccaatttc	Protospacer
**************************..*********

52. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 875104-875140, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

53. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 1144010-1144046, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

54. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 1144066-1144102, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

55. spacer 3.2|875216|37|NZ_CP048431|CRT matches to position: 2295442-2295478, mismatch: 2, identity: 0.946

aacttgcacattattgtaagctgacttttcgtcagct	CRISPR spacer
aacttgcacattattgtaagctgactttccgccagct	Protospacer
****************************.**.*****

56. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 69461-69497, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtctgtagaatttcctttcgaaattc	Protospacer
*************************.***.*******

57. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 1144336-1144372, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

58. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 1194263-1194299, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

59. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 879240-879276, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
*************.***************.*******

60. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 1095246-1095282, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

61. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 1841489-1841525, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

62. spacer 3.3|875272|37|NZ_CP048431|CRT matches to position: 2137252-2137288, mismatch: 2, identity: 0.946

caacttgcattgtctgtagaatttctttttgaaattc	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
************.****************.*******

63. spacer 7.1|2137215|34|NZ_CP048431|CRISPRCasFinder matches to position: 669310-669343, mismatch: 2, identity: 0.941

attgggaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttgggctccat	Protospacer
**************************** .****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048431_1	1.1\|283414\|29\|NZ_CP048431\|CRISPRCasFinder	283414-283442	29	NZ_CP018781	Ochrobactrum pituitosum strain AA2 plasmid pOAAA2, complete sequence	148987-149015	7	0.759

1. spacer 1.1|283414|29|NZ_CP048431|CRISPRCasFinder matches to NZ_CP018781 (Ochrobactrum pituitosum strain AA2 plasmid pOAAA2, complete sequence) position: , mismatch: 7, identity: 0.759

tttcttttcgaaattctctatgttggggc	CRISPR spacer
accatcttcgtaatgctctatgttggggc	Protospacer
 .. *.**** *** **************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 62485

Staphylococcus_phage(69.7%)

protease,portal,head,capsid,tail,holin,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031773897.1\|1366_2605_+\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	1.7e-233	99.5
WP_031883906.1\|2588_3362_+\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	1.9e-134	97.7
WP_031883907.1\|3373_4537_+\|capsid	phage major capsid protein	Q4ZCT8	Staphylococcus_virus	2.7e-217	99.5
WP_000050977.1\|4605_4884_+\|head,tail	phage gp6-like head-tail connector protein	R4WAL3	Staphylococcus_phage	3.5e-46	100.0
WP_000395499.1\|4895_5228_+	hypothetical protein	A0A2I6PEH8	Staphylococcus_phage	3.1e-57	100.0
WP_164025726.1\|5224_5626_+	hypothetical protein	R4WAN5	Staphylococcus_phage	1.8e-67	99.2
WP_001636966.1\|5626_6022_+	DUF3168 domain-containing protein	R4WAV1	Staphylococcus_phage	4.4e-66	99.2
WP_031865961.1\|6056_6698_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	1.7e-120	99.5
WP_031916056.1\|6789_7245_+	Ig domain-containing protein	A0A2I6PF45	Staphylococcus_phage	1.4e-76	98.7
WP_000589165.1\|7302_7653_+	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|7694_7853_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_164025728.1\|7866_14043_+\|tail	phage tail tape measure protein	A0A2I6PDS2	Staphylococcus_phage	0.0e+00	97.2
WP_001190533.1\|14042_14867_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_098692151.1\|14875_16456_+	peptidase	Q4ZD01	Staphylococcus_virus	3.1e-304	98.7
WP_031786856.1\|16455_16746_+	hypothetical protein	U5U457	Staphylococcus_phage	6.0e-49	99.0
WP_031906531.1\|16761_18672_+	hypothetical protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	99.8
WP_164026468.1\|18671_20138_+\|plate	BppU family phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	1.3e-272	99.8
WP_001166599.1\|20137_20527_+	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_000916020.1\|20519_20684_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466784.1\|20729_21029_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_164025730.1\|21164_21467_+\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	4.5e-47	97.0
WP_164025732.1\|21477_22932_+	CHAP domain-containing protein	A0A0N6WMR3	Staphylococcus_phage	3.0e-282	96.9
WP_098692146.1\|23766_24744_-	GMP reductase	Q4ZCY7	Staphylococcus_virus	8.8e-185	99.1
WP_000669702.1\|25581_27945_+	MAP domain-containing protein	NA	NA	NA	NA
WP_001068523.1\|28223_29510_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000990056.1\|29709_29808_+	hypothetical protein	NA	NA	NA	NA
WP_000681968.1\|30050_30227_+	hypothetical protein	NA	NA	NA	NA
WP_000691584.1\|30485_30866_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000991303.1\|30862_31759_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000645725.1\|31759_32440_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000763048.1\|32436_33309_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_001221651.1\|33308_34049_+	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000182842.1\|34114_34678_-	thioredoxin family protein	NA	NA	NA	NA
WP_000966288.1\|34798_35323_+	membrane protein	NA	NA	NA	NA
WP_001033971.1\|35382_35940_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000713070.1\|35936_36779_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001188074.1\|36835_37876_-	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000267034.1\|38326_38500_+	hypothetical protein	NA	NA	NA	NA
WP_000205106.1\|39072_39474_-	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000181322.1\|39743_40772_+	lactonase family protein	NA	NA	NA	NA
WP_001021216.1\|40891_42271_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_001790680.1\|42322_42496_+	hypothetical protein	NA	NA	NA	NA
WP_001140871.1\|42690_43620_-	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_164025735.1\|43672_44233_-	isochorismatase family protein	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_000275706.1\|44604_45702_+	pectate lyase	U5PWM6	Bacillus_phage	2.5e-47	34.9
WP_000323164.1\|45906_47469_+	SLC13 family permease	NA	NA	NA	NA
WP_001802312.1\|47479_47587_-	hypothetical protein	NA	NA	NA	NA
WP_164025737.1\|47658_48453_-	prephenate dehydratase	NA	NA	NA	NA
WP_000897635.1\|48472_49549_-	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_000284433.1\|49732_51202_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.5e-108	45.1
WP_000040866.1\|51194_52016_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000011542.1\|52286_52889_+	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000669861.1\|52869_53043_+	NETI motif-containing protein	NA	NA	NA	NA
WP_000434934.1\|53335_53662_-	staphostatin A	NA	NA	NA	NA
WP_000827750.1\|53692_54859_-\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000572878.1\|55718_57014_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_164025739.1\|57122_57425_+	hypothetical protein	NA	NA	NA	NA
WP_000272070.1\|57596_58289_+	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_000992921.1\|58285_60478_+	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_024273295.1\|60481_62485_+	NAD-dependent DNA ligase LigA	A0A0A8J9A9	Ralstonia_phage	2.3e-110	36.2

DBSCAN-SWA_2

69603 : 74631

Catovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001231451.1\|69603_70551_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	1.2e-16	27.8
WP_001147864.1\|70631_71993_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A1X9I6F4	Streptococcus_phage	6.3e-104	43.8
WP_000548781.1\|72162_72693_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_000140176.1\|72939_74010_+	DNA polymerase IV	NA	NA	NA	NA
WP_000613865.1\|74076_74631_-	3'-5' exonuclease	B5WZL1	Staphylococcus_phage	1.2e-29	35.7

DBSCAN-SWA_3

78084 : 78498

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001549145.1\|78084_78498_+	hypothetical protein	A0A1Q1PVU5	Staphylococcus_phage	5.1e-17	37.7

DBSCAN-SWA_4

83552 : 84182

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000153535.1\|83552_84182_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.1e-06	30.8

DBSCAN-SWA_5

99661 : 101398

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000597230.1\|99661_101398_+	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	3.8e-53	30.2

DBSCAN-SWA_6

117843 : 118572

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001144055.1\|117843_118572_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-36	42.7

DBSCAN-SWA_7

129165 : 129510

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000290301.1\|129165_129510_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7

DBSCAN-SWA_8

139248 : 139989

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000216874.1\|139248_139989_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8

DBSCAN-SWA_9

151325 : 167372

Staphylococcus_phage(90.91%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000711493.1\|151325_152672_-	DUF4041 domain-containing protein	M1NRY5	Streptococcus_phage	9.6e-65	50.8
WP_000595640.1\|152838_153435_-	membrane protein	NA	NA	NA	NA
WP_000878802.1\|155056_155977_+	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	2.3e-174	100.0
WP_000782446.1\|155978_156962_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000543856.1\|157331_158123_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000550252.1\|158127_158601_-	hypothetical protein	NA	NA	NA	NA
WP_024273481.1\|158856_159075_+	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	1.5e-23	77.8
WP_001092776.1\|159548_160118_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	2.6e-51	62.6
WP_001039433.1\|161080_161788_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_164025765.1\|161912_162635_+\|protease	trypsin-like serine protease	A0A2H4PQN0	Staphylococcus_phage	3.2e-131	99.6
WP_001038872.1\|162692_163412_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_017431874.1\|163532_164252_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.7e-129	97.9
WP_001791797.1\|164316_164451_+	hypothetical protein	NA	NA	NA	NA
WP_072433588.1\|164431_166171_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.8e-287	98.3
WP_000072589.1\|166163_167372_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	9.3e-35	31.5

DBSCAN-SWA_10

176566 : 223311

Staphylococcus_phage(94.59%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864143.1\|176566_177124_+	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.7e-77	96.2
WP_000414214.1\|177320_177893_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.1e-25	96.6
WP_000627537.1\|177993_178335_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000669027.1\|178375_179002_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.3e-90	93.8
WP_000070655.1\|179077_180073_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	6.2e-77	98.8
WP_001795535.1\|180153_180804_-	calcium-binding protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_072433592.1\|181106_181562_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.9
WP_000348374.1\|181720_183199_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	8.1e-283	97.4
WP_000778525.1\|183203_184205_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.2e-186	97.9
WP_000718107.1\|184201_184459_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672014.1\|184524_184998_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_001834463.1\|185002_185749_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000109906.1\|186126_187719_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933822.1\|188090_189284_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000366163.1\|189408_190317_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000453314.1\|190528_191362_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000623478.1\|191744_192098_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_001200542.1\|192094_192460_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091445.1\|192715_193018_-	hypothetical protein	NA	NA	NA	NA
WP_001096494.1\|193277_193991_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168901.1\|194430_195066_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030469.1\|195361_195805_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001153742.1\|195791_196235_-	competence protein ComK	NA	NA	NA	NA
WP_000671052.1\|196347_196818_-	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_000384171.1\|197016_197241_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|197516_198371_+	autolysin	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000989122.1\|198457_199750_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	9.4e-227	99.3
WP_000221177.1\|199749_200064_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_001261668.1\|200586_202089_+	FAD-dependent oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000384185.1\|202581_203613_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.0e-196	98.8
WP_000493892.1\|203619_204252_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_001159022.1\|204262_205444_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_164025769.1\|205456_205921_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	3.8e-69	96.1
WP_001196354.1\|206042_207044_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001790712.1\|207155_207275_+	hypothetical protein	NA	NA	NA	NA
WP_000266096.1\|207277_208105_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000757543.1\|208676_209078_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000764419.1\|209197_209761_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000526539.1\|209757_210711_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_164025772.1\|210820_212002_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	2.1e-217	99.7
WP_164025775.1\|212292_214707_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_000836465.1\|214728_215040_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_164025778.1\|215365_221926_+	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	1.0e-308	98.9
WP_000285020.1\|222042_223311_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	9.1e-57	99.1

DBSCAN-SWA_11

234363 : 239691

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001091387.1\|234363_235221_+	DUF1444 domain-containing protein	A0A2H4PQY3	Staphylococcus_phage	6.8e-72	100.0
WP_001048368.1\|235249_235846_+	DUF4479 domain-containing protein	NA	NA	NA	NA
WP_000118284.1\|235866_239691_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.0e-83	47.0

DBSCAN-SWA_12

256429 : 259060

Cronobacter_phage(50.0%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000186029.1\|256429_257692_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	2.7e-85	42.1
WP_001279338.1\|257785_259060_-\|protease	trypsin-like serine protease	A0A1B1IRD3	uncultured_Mediterranean_phage	1.7e-10	29.0

DBSCAN-SWA_13

262829 : 266964

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025784.1\|262829_264434_-	phosphoglycerate dehydrogenase	A0A2H4PQU8	Staphylococcus_phage	1.2e-114	100.0
WP_164025786.1\|264420_265581_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_000553927.1\|265694_266141_-	OsmC family protein	NA	NA	NA	NA
WP_000174285.1\|266220_266964_+	glycerophosphoryl diester phosphodiesterase	M1HTS7	Paramecium_bursaria_Chlorella_virus	4.9e-18	30.0

DBSCAN-SWA_14

284695 : 287893

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001836688.1\|284695_287893_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	1.0e-136	30.6

DBSCAN-SWA_15

292826 : 294584

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001232648.1\|292826_294584_+	pyruvate kinase	A0A2H4PQU5	Staphylococcus_phage	2.6e-41	100.0

DBSCAN-SWA_16

301445 : 309609

Feldmannia_irregularis_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080028.1\|301445_302150_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	1.6e-07	28.7
WP_015445861.1\|302149_303811_+	PAS domain S-box protein	W8CYF6	Bacillus_phage	5.8e-35	39.4
WP_164025807.1\|304309_305797_+	hypothetical protein	NA	NA	NA	NA
WP_001038308.1\|306090_308721_+	DNA polymerase I	A8E2B3	Enterococcus_phage	6.1e-47	33.0
WP_001114467.1\|308736_309609_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	2.0e-42	38.2

DBSCAN-SWA_17

313524 : 324677

Brevibacillus_phage(20.0%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001670575.1\|313524_314445_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	4.8e-31	29.4
WP_001790562.1\|314537_314660_+	hypothetical protein	NA	NA	NA	NA
WP_024273554.1\|314857_316795_+\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	1.7e-115	35.8
WP_000049145.1\|317220_318714_+	amino acid permease	NA	NA	NA	NA
WP_001791162.1\|318942_319470_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	33.1
WP_001125540.1\|319498_319699_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_001138360.1\|319745_320102_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_000032657.1\|320243_320852_+	NUDIX domain-containing protein	A0A060AB76	Staphylococcus_phage	6.6e-21	35.9
WP_164025812.1\|320870_321800_+	hypothetical protein	NA	NA	NA	NA
WP_001790560.1\|321804_321915_+	hypothetical protein	NA	NA	NA	NA
WP_070047466.1\|321962_323264_+	trigger factor	NA	NA	NA	NA
WP_000472293.1\|323414_324677_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.1e-139	61.7

DBSCAN-SWA_18

335765 : 338396

Catovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000425363.1\|335765_338396_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	2.2e-153	40.4

DBSCAN-SWA_19

348591 : 384144

uncultured_Mediterranean_phage(18.75%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005768.1\|348591_349596_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_070004486.1\|349597_350623_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|350645_351785_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|351803_352064_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_000749795.1\|352338_354618_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_000594991.1\|354820_357094_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	5.2e-63	28.8
WP_000364542.1\|357115_357634_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_001058583.1\|358061_360251_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	6.9e-12	37.7
WP_000869983.1\|360262_360715_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_000717800.1\|360711_361587_+	SH3 domain-containing protein	A0A0N9SGH1	Paenibacillus_phage	4.7e-12	33.7
WP_000590824.1\|362047_363310_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_000044799.1\|363325_365092_+\|tRNA	aspartate--tRNA ligase	A0A2K9L0E9	Tupanvirus	1.3e-16	27.3
WP_001790559.1\|365424_365553_+	hypothetical protein	NA	NA	NA	NA
WP_000682646.1\|365552_366326_+\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
WP_000102740.1\|366486_367761_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-105	50.7
WP_000704122.1\|367845_368268_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_000752909.1\|368367_368550_+	CsbD family protein	NA	NA	NA	NA
WP_000009238.1\|368589_368736_+	hypothetical protein	NA	NA	NA	NA
WP_000985895.1\|368972_369986_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_000409158.1\|370297_371440_+	cysteine desulfurase	A0A1X7QGF3	Faustovirus	5.4e-32	30.8
WP_164025819.1\|371440_372559_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000567017.1\|373193_373862_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_164025822.1\|373863_376341_+	ATP-dependent RecD-like DNA helicase	A0A0K2FLP8	Brevibacillus_phage	1.9e-66	28.9
WP_000734081.1\|376683_379314_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.2e-64	34.4
WP_000426912.1\|379376_379637_+	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_000939059.1\|379640_380069_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_000134779.1\|380083_380392_+	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_000342266.1\|380676_381315_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	1.6e-09	28.8
WP_000137775.1\|381317_382241_+	U32 family peptidase	NA	NA	NA	NA
WP_162646513.1\|382252_383521_+	U32 family peptidase	Q6DW11	Phage_TP	1.5e-35	31.4
WP_000648617.1\|383520_384144_+	uridine kinase	A0A1V0SAA3	Catovirus	2.8e-35	41.1

DBSCAN-SWA_20

398216 : 405158

Indivirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_072353822.1\|398216_398903_+	ComEA family DNA-binding protein	A0A1V0SDW0	Indivirus	7.5e-05	30.4
WP_000439693.1\|398994_399456_+	ComE operon protein 2	A7KUY9	Bacillus_phage	3.6e-35	58.8
WP_164026471.1\|399514_401662_+	DNA internalization-related competence protein ComEC/Rec2	Q332C0	Clostridium_botulinum_C_phage	2.7e-32	32.2
WP_001282562.1\|401718_402693_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_001274017.1\|402737_402989_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_000368341.1\|403334_405158_+	elongation factor 4	A0A1S5SF82	Streptococcus_phage	6.1e-22	25.1

DBSCAN-SWA_21

408594 : 411702

Micromonas_pusilla_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025830.1\|408594_410427_+	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.2e-137	46.7
WP_001119021.1\|410562_411702_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.2e-26	25.8

DBSCAN-SWA_22

418170 : 419118

Rhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001117767.1\|418170_419118_+	PhoH family protein	L7TP00	Rhizobium_phage	6.4e-47	46.8

DBSCAN-SWA_23

422172 : 435918

Klosneuvirus(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001030080.1\|422172_423564_-\|tRNA	glycine--tRNA ligase	A0A1V0SIF1	Klosneuvirus	4.7e-46	27.4
WP_001797828.1\|423898_424522_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000411298.1\|424532_425351_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_001217257.1\|425411_427229_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3
WP_001283055.1\|427452_428559_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_164025836.1\|428689_429367_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000683929.1\|429369_430470_+	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_001062187.1\|430583_431930_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000924220.1\|431939_432830_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001213908.1\|432955_433741_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000564316.1\|433782_434646_+	metal ABC transporter permease	NA	NA	NA	NA
WP_001095260.1\|434632_435043_+	transcriptional repressor	NA	NA	NA	NA
WP_000863556.1\|435318_435918_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	9.2e-60	54.7

DBSCAN-SWA_24

442091 : 442715

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_117223063.1\|442091_442715_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.7e-30	36.6

DBSCAN-SWA_25

448259 : 451071

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019691.1\|448259_449606_+	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	E3SN07	Prochlorococcus_phage	1.7e-61	39.2
WP_000202188.1\|449598_451071_+	glycine dehydrogenase subunit 2	E3SN07	Prochlorococcus_phage	2.8e-81	41.3

DBSCAN-SWA_26

458570 : 465141

Indivirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001286928.1\|458570_459908_+	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	1.6e-43	37.7
WP_000159865.1\|459900_460131_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_000183381.1\|460108_460990_+	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	3.4e-10	25.8
WP_001124985.1\|461421_461874_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_164025840.1\|461889_463569_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001291538.1\|463719_465141_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	8.7e-40	26.3

DBSCAN-SWA_27

471969 : 473376

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000193707.1\|471969_473376_+	NADP-dependent phosphogluconate dehydrogenase	A0A222YX62	Synechococcus_phage	4.3e-31	31.1

DBSCAN-SWA_28

479801 : 481286

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025845.1\|479801_481286_-	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	1.2e-79	37.6

DBSCAN-SWA_29

486952 : 498009

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000447732.1\|486952_487840_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	4.3e-37	31.4
WP_001183439.1\|487917_488424_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_000273371.1\|488515_489247_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	7.9e-05	21.8
WP_000368656.1\|489239_489782_+	SMC-Scp complex subunit ScpB	NA	NA	NA	NA
WP_000159577.1\|489774_490512_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000064078.1\|490644_491370_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-45	43.0
WP_000987769.1\|491350_493102_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
WP_164025848.1\|493346_494291_+	DUF1672 family protein	NA	NA	NA	NA
WP_164025849.1\|494679_495225_+	ECF transporter S component	NA	NA	NA	NA
WP_001151997.1\|495330_495579_-	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001163801.1\|495686_496640_+	hypothetical protein	NA	NA	NA	NA
WP_000902119.1\|496629_498009_+	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6

DBSCAN-SWA_30

507419 : 512886

Bacillus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001043863.1\|507419_507692_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000450555.1\|508122_508695_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_000774685.1\|508697_509423_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_016169114.1\|509439_510384_+	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000442480.1\|510475_510925_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_000789522.1\|511133_511334_+	hypothetical protein	NA	NA	NA	NA
WP_001269930.1\|511719_512886_+	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-34	32.1

DBSCAN-SWA_31

516548 : 517124

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000005212.1\|516548_517124_+	IDEAL domain-containing protein	G3MAV7	Bacillus_virus	2.1e-08	27.2

DBSCAN-SWA_32

520496 : 528002

unidentified_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000361549.1\|520496_521699_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.9e-35	43.3
WP_164025859.1\|521685_522657_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_164025861.1\|522680_525374_+	ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	3.7e-47	34.4
WP_000858782.1\|525695_526988_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
WP_000362218.1\|527315_528002_+	DnaD domain-containing protein	Q938N2	Temperate_phage	1.2e-07	32.6

DBSCAN-SWA_33

531740 : 532418

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025863.1\|531740_532418_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	1.9e-24	35.5

DBSCAN-SWA_34

542114 : 542993

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001133022.1\|542114_542993_+	5'-3' exonuclease	S5M4P0	Bacillus_phage	1.4e-19	29.5

DBSCAN-SWA_35

581950 : 591340

Staphylococcus_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000282171.1\|581950_582655_-	queuosine precursor transporter	A0A2H4J2N7	uncultured_Caudovirales_phage	8.4e-12	23.8
WP_001795441.1\|582899_583094_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_000691943.1\|583105_583357_+	hypothetical protein	NA	NA	NA	NA
WP_000404641.1\|583394_584519_+	virulence factor	NA	NA	NA	NA
WP_000995287.1\|584534_584972_+	BrxA/BrxB family bacilliredoxin	NA	NA	NA	NA
WP_000934885.1\|585395_586352_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.6e-167	85.2
WP_000175746.1\|586551_587031_+	dihydrofolate reductase	A0A0N9S8H6	Staphylococcus_phage	2.0e-73	79.9
WP_000166059.1\|587045_587885_+	fatty acid kinase FakB2	A0A0N9SI50	Staphylococcus_phage	2.3e-48	77.3
WP_000159902.1\|587970_588504_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_000913315.1\|588496_588925_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_000473652.1\|588936_589437_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_000801007.1\|589436_589658_+	hypothetical protein	NA	NA	NA	NA
WP_000342125.1\|589849_591340_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	2.3e-22	30.5

DBSCAN-SWA_36

594748 : 596760

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000192137.1\|594748_595408_+	response regulator transcription factor ArlR	W8CYM9	Bacillus_phage	1.1e-34	33.8
WP_000166802.1\|595404_596760_+	sensor histidine kinase ArlS	A0A1V0SGX0	Hokovirus	3.5e-14	27.8

DBSCAN-SWA_37

602925 : 603717

Halovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025867.1\|602925_603717_+	MoxR family ATPase	R4TG24	Halovirus	3.3e-12	34.2

DBSCAN-SWA_38

607257 : 612288

Lactobacillus_phage(33.33%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000138420.1\|607257_608394_-	toxic anion resistance protein	A0A291I9K4	Lactobacillus_phage	3.7e-33	28.0
WP_001788788.1\|608425_609055_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis protein	NA	NA	NA	NA
WP_001215907.1\|609073_609343_-	acylphosphatase	NA	NA	NA	NA
WP_000269923.1\|609505_609814_+	DUF1033 family protein	NA	NA	NA	NA
WP_000809131.1\|609984_610185_+	cold-shock protein	Q9AZD3	Lactococcus_phage	8.4e-18	66.2
WP_000876201.1\|610381_610783_+	sarA expression modulator protein Msa	NA	NA	NA	NA
WP_164025869.1\|611022_612288_-	diaminopimelate decarboxylase	A0A0P0YM38	Yellowstone_lake_phycodnavirus	1.4e-12	23.2

DBSCAN-SWA_39

620133 : 621735

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000942300.1\|620133_621735_-	ATP-binding cassette domain-containing protein	A0A1V0SKJ1	Klosneuvirus	5.5e-51	25.7

DBSCAN-SWA_40

626819 : 630273

Indivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000079447.1\|626819_627671_+	phosphate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	8.9e-16	29.7
WP_000974848.1\|627677_628319_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_000077571.1\|628458_630273_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.1e-154	47.1

DBSCAN-SWA_41

633687 : 634389

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571259.1\|633687_634389_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.0e-13	30.3

DBSCAN-SWA_42

641900 : 644255

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000153621.1\|641900_642683_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	5.5e-28	36.7
WP_164025876.1\|642684_643683_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	7.2e-33	34.5
WP_000604816.1\|643688_644255_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.3e-23	32.1

DBSCAN-SWA_43

648573 : 649836

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000283016.1\|648573_649836_-	Y-family DNA polymerase	O64031	Bacillus_phage	2.6e-96	44.3

DBSCAN-SWA_44

659495 : 663889

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001289562.1\|659495_661898_-	DNA topoisomerase IV subunit A	A0A172JHV7	Bacillus_phage	7.9e-94	32.4
WP_001548666.1\|661897_663889_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	8.0e-116	40.5

DBSCAN-SWA_45

669824 : 671471

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001088978.1\|669824_671471_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	2.5e-22	24.4

DBSCAN-SWA_46

675139 : 676261

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000691304.1\|675139_676261_-	exonuclease SbcCD subunit D	A0A1X9I9U0	Staphylococcus_phage	4.3e-10	22.7

DBSCAN-SWA_47

680410 : 686066

Phage_Wrath(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001208755.1\|680410_681034_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	5.9e-17	63.8
WP_000380723.1\|681413_682277_-	CAP domain-containing protein	U5Q0C0	Bacillus_phage	4.1e-16	41.5
WP_001791425.1\|682350_682455_+	hypothetical protein	NA	NA	NA	NA
WP_000688122.1\|682451_683429_-	GMP reductase	Q4ZCY7	Staphylococcus_virus	8.0e-186	99.7
WP_001085655.1\|683585_683855_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_001265708.1\|684308_684458_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_164025891.1\|684548_686066_-	catalase	A0A2K9L0T1	Tupanvirus	2.3e-91	43.2

DBSCAN-SWA_48

696202 : 700478

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000841351.1\|696202_696736_-	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	3.4e-21	43.5
WP_001027143.1\|696874_697063_+	hypothetical protein	NA	NA	NA	NA
WP_000202390.1\|697175_697778_-	response regulator transcription factor	NA	NA	NA	NA
WP_164025893.1\|697774_698866_-	sensor histidine kinase	NA	NA	NA	NA
WP_000603969.1\|698869_699601_-	ABC transporter permease	NA	NA	NA	NA
WP_164025895.1\|699569_700478_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.2e-23	26.2

DBSCAN-SWA_49

709516 : 711124

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001002340.1\|709516_709723_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_075111596.1\|710019_710238_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	6.4e-19	73.1
WP_001814546.1\|710926_711124_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	50.0

DBSCAN-SWA_50

716199 : 716676

Fowlpox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448079.1\|716199_716676_+	glutathione peroxidase	Q70H87	Fowlpox_virus	7.9e-22	37.3

DBSCAN-SWA_51

722618 : 729100

Acanthocystis_turfacea_Chlorella_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001103743.1\|722618_723437_-	aquaporin family protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	2.4e-26	35.1
WP_001077635.1\|723911_724454_-	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_000516264.1\|724459_726469_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.8e-60	30.7
WP_164025900.1\|726481_729100_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	6.5e-41	23.8

DBSCAN-SWA_52

738514 : 739558

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000368166.1\|738514_739558_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	9.3e-124	69.2

DBSCAN-SWA_53

743758 : 749302

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000664778.1\|743758_745045_-	insulinase family protein	G3MBJ8	Bacillus_virus	6.7e-15	27.9
WP_000089942.1\|745044_746310_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	9.1e-41	26.8
WP_001293307.1\|746340_747054_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_001806691.1\|747058_749302_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	6.9e-84	47.7

DBSCAN-SWA_54

754442 : 766255

Klosneuvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864186.1\|754442_755414_-	riboflavin biosynthesis protein RibF	A0A1V0SJE1	Klosneuvirus	6.6e-07	31.3
WP_000282298.1\|755428_756346_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000097322.1\|756514_756865_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000043635.1\|757250_759368_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	2.4e-25	25.1
WP_000020853.1\|759372_759690_-	YlxQ family RNA-binding protein	NA	NA	NA	NA
WP_000727423.1\|759686_759971_-	YlxR family protein	NA	NA	NA	NA
WP_000097460.1\|759991_761167_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000036633.1\|761187_761655_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_001834826.1\|761944_766255_-	PolC-type DNA polymerase III	A0A0A8WJ41	Clostridium_phage	3.5e-23	41.2

DBSCAN-SWA_55

770503 : 771274

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000473705.1\|770503_771274_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	7.3e-25	41.5

DBSCAN-SWA_56

776048 : 787253

Erwinia_phage(20.0%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025906.1\|776048_777452_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IDZ7	Erwinia_phage	2.2e-27	25.6
WP_000072681.1\|777517_778063_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_001015597.1\|778059_778956_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.6e-31	31.5
WP_000195254.1\|779372_780680_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_001557331.1\|780835_782911_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	1.7e-105	39.2
WP_000931873.1\|783084_783957_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_000110251.1\|784280_785189_-	succinate--CoA ligase subunit alpha	A0A2K9L1S3	Tupanvirus	3.0e-17	33.2
WP_164025908.1\|785210_786377_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_000176409.1\|786485_787253_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	2.5e-25	44.1

DBSCAN-SWA_57

800863 : 803113

Acanthamoeba_polyphaga_mimivirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000043237.1\|800863_801595_-	ribonuclease III	A0A0G2Y7P9	Acanthamoeba_polyphaga_mimivirus	5.9e-24	28.8
WP_000426914.1\|801710_801944_-	acyl carrier protein	E3SSM9	Prochlorococcus_phage	1.6e-07	63.3
WP_164025911.1\|802378_803113_-	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-17	30.3

DBSCAN-SWA_58

813483 : 815478

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025926.1\|813483_815478_-	Stk1 family PASTA domain-containing Ser/Thr kinase	M1PCM5	Moumouvirus	5.5e-24	34.8

DBSCAN-SWA_59

818625 : 819561

Prochlorococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161291.1\|818625_819561_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.7e-10	28.0

DBSCAN-SWA_60

824574 : 826831

Methanothermobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000722165.1\|824574_825774_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.2e-42	32.9
WP_000933956.1\|825989_826208_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_164025928.1\|826207_826831_-	guanylate kinase	A0A143DIC6	Abalone_herpesvirus	1.6e-22	34.7

DBSCAN-SWA_61

830145 : 830757

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001040248.1\|830145_830757_-	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	1.6e-27	33.8

DBSCAN-SWA_62

834724 : 839335

Halovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025937.1\|834724_835825_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	7.4e-63	36.8
WP_000767028.1\|835826_837101_-	dihydroorotase	NA	NA	NA	NA
WP_001016166.1\|837118_838000_-	aspartate carbamoyltransferase catalytic subunit	A0A1J0F9B8	Only_Syngen_Nebraska_virus	4.6e-31	33.9
WP_001178619.1\|838027_839335_-	uracil permease	Q9KX94	Enterobacteria_phage	3.3e-54	34.0

DBSCAN-SWA_63

843872 : 846626

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000384691.1\|843872_846626_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	3.6e-90	28.0

DBSCAN-SWA_64

866210 : 866399

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001245802.1\|866210_866399_-	hypothetical protein	A0A0K1LL29	Staphylococcus_phage	3.8e-20	86.9

DBSCAN-SWA_65

875482 : 879961

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001802045.1\|875482_875707_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	5.6e-18	71.4
WP_000765708.1\|875663_875810_-	hypothetical protein	NA	NA	NA	NA
WP_000857485.1\|876482_877442_+	beta-channel forming cytolysin	A0A2H4PQH7	Staphylococcus_phage	1.3e-34	30.3
WP_000231632.1\|877918_878152_+	hypothetical protein	NA	NA	NA	NA
WP_001032816.1\|878773_878959_+	hypothetical protein	NA	NA	NA	NA
WP_000669528.1\|879610_879961_-	complement inhibitor SCIN family protein	A7TWS0	Staphylococcus_phage	2.4e-20	49.1

DBSCAN-SWA_66

891446 : 896004

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001018928.1\|891446_891761_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	46.6
WP_164025946.1\|891933_894282_-	endonuclease MutS2	F2QAF8	Phaeocystis_pouchetii_virus	3.8e-16	25.7
WP_000161941.1\|894291_896004_-	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	8.9e-15	24.0

DBSCAN-SWA_67

901077 : 902136

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000003566.1\|901077_902136_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5

DBSCAN-SWA_68

914079 : 916987

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000401377.1\|914079_914562_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
WP_001263796.1\|914563_915106_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_000814565.1\|915175_915565_+	hypothetical protein	NA	NA	NA	NA
WP_001049150.1\|915567_915822_-	YlbG family protein	NA	NA	NA	NA
WP_164025948.1\|916060_916987_+	glycerophosphodiester phosphodiesterase	M1I1K8	Paramecium_bursaria_Chlorella_virus	1.7e-12	26.2

DBSCAN-SWA_69

928505 : 930353

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000182654.1\|928505_930353_-	translational GTPase TypA	A0A2K5B2A5	Erysipelothrix_phage	1.8e-21	26.2

DBSCAN-SWA_70

938488 : 947321

Mycoplasma_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000433551.1\|938488_939583_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.4e-37	44.3
WP_001020625.1\|939595_940135_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000455597.1\|940278_940554_-	UPF0223 family protein	NA	NA	NA	NA
WP_000260117.1\|940721_942128_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.2e-46	29.1
WP_000863439.1\|942131_943424_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_000068176.1\|943514_944492_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_000035320.1\|944495_945608_-	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	A0A0K0KW14	Prochlorococcus_phage	1.4e-05	27.8
WP_000668339.1\|945778_946405_-	cell-wall-binding lipoprotein	NA	NA	NA	NA
WP_000957036.1\|946769_947321_+	peptide deformylase	E3SLL2	Synechococcus_phage	1.6e-13	42.2

DBSCAN-SWA_71

954787 : 959167

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001289618.1\|954787_955021_+	glutaredoxin family protein	G3MBF0	Bacillus_virus	8.4e-09	38.7
WP_000040058.1\|955257_956976_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_000437472.1\|956978_957245_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_000505966.1\|957398_957941_-	hypothetical protein	NA	NA	NA	NA
WP_000685067.1\|957994_959167_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.0e-75	42.8

DBSCAN-SWA_72

962535 : 977297

Prochlorococcus_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000921973.1\|962535_963936_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-10	26.3
WP_000273253.1\|963928_964735_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_164025951.1\|965001_966249_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_000709277.1\|966270_967749_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.2e-77	51.8
WP_164025952.1\|967763_968330_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.8e-28	39.6
WP_164025953.1\|968332_969361_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.0e-61	41.7
WP_000483720.1\|969353_970838_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000032740.1\|970816_973006_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000666806.1\|972998_973670_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000848350.1\|973671_973935_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|973934_974639_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_164025954.1\|974642_975767_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861572.1\|975753_976236_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_000225837.1\|976436_977297_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	5.3e-40	39.2

DBSCAN-SWA_73

987752 : 991523

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001074554.1\|987752_991523_+	bifunctional autolysin	A0A1J0MFB0	Staphylococcus_phage	1.1e-54	37.6

DBSCAN-SWA_74

995188 : 1011553

Staphylococcus_phage(33.33%)

holin,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025959.1\|995188_996199_+\|protease	trypsin-like serine protease	A0A2H4PQP7	Staphylococcus_phage	3.1e-15	31.7
WP_001089094.1\|996280_997462_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_164025963.1\|997499_997829_+\|protease	cysteine protease inhibitor staphostatin B	NA	NA	NA	NA
WP_000184945.1\|998066_998888_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150197.1\|998880_999684_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_164025965.1\|999670_1001344_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_001816819.1\|1001330_1002542_-	isochorismate synthase	NA	NA	NA	NA
WP_001791731.1\|1002618_1002723_-	hypothetical protein	NA	NA	NA	NA
WP_164025967.1\|1002873_1003812_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620949.1\|1003863_1004415_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001788574.1\|1004504_1004795_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	7.5e-07	38.0
WP_001790177.1\|1004858_1004990_+	hypothetical protein	NA	NA	NA	NA
WP_000766009.1\|1006483_1006840_+	DoxX family protein	NA	NA	NA	NA
WP_001792054.1\|1006928_1007066_-	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_001795266.1\|1007206_1007497_+	hypothetical protein	NA	NA	NA	NA
WP_000571167.1\|1007584_1008226_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
WP_000668627.1\|1008222_1008543_-	YxeA family protein	NA	NA	NA	NA
WP_000870827.1\|1008545_1010510_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_001797239.1\|1010553_1010826_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_031763719.1\|1010835_1010937_-	hypothetical protein	NA	NA	NA	NA
WP_164026481.1\|1011475_1011553_-\|holin	putative holin-like toxin	NA	NA	NA	NA

DBSCAN-SWA_75

1018420 : 1023631

Pithovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025971.1\|1018420_1020745_-	PDZ domain-containing protein	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000928413.1\|1020963_1021767_-	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001049951.1\|1022068_1023631_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2

DBSCAN-SWA_76

1042562 : 1044371

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000082725.1\|1042562_1044371_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5

DBSCAN-SWA_77

1050184 : 1052154

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000427769.1\|1050184_1051165_-	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-16	34.1
WP_001067040.1\|1051167_1052154_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.8e-15	30.0

DBSCAN-SWA_78

1055805 : 1057819

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000786736.1\|1055805_1056747_-	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	1.6e-05	26.9
WP_070047531.1\|1056736_1057819_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.4e-19	28.8

DBSCAN-SWA_79

1066413 : 1073223

Micromonas_sp._RCC1109_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025982.1\|1066413_1067559_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	3.3e-05	25.6
WP_001047069.1\|1067668_1068538_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000353954.1\|1068596_1071206_-	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	5.5e-117	34.3
WP_001044219.1\|1071408_1073223_-	acetyltransferase	B5WZU0	Pseudomonas_phage	3.0e-37	34.2

DBSCAN-SWA_80

1080354 : 1084008

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000154930.1\|1080354_1084008_-	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	3.5e-24	24.5

DBSCAN-SWA_81

1094162 : 1101339

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000185319.1\|1094162_1095092_+	glycerophosphodiester phosphodiesterase	A0A220BYK6	Staphylococcus_phage	3.7e-39	37.9
WP_000138487.1\|1095613_1096858_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_000167314.1\|1096966_1098157_-	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	1.3e-33	29.7
WP_000838034.1\|1098464_1099592_-	NADH-dependent flavin oxidoreductase	NA	NA	NA	NA
WP_001067294.1\|1099953_1100331_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_000035058.1\|1100745_1101339_-	peptidyl-prolyl cis-trans isomerase	A0A076FI46	Aureococcus_anophage	1.1e-25	41.3

DBSCAN-SWA_82

1111259 : 1114887

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164025990.1\|1111259_1112735_-	leucyl aminopeptidase family protein	Q6GYZ8	Mycoplasma_phage	6.9e-48	35.8
WP_164025992.1\|1112865_1114074_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_001143495.1\|1114527_1114887_-	iron-sulfur cluster assembly accessory protein	A0A2H4N7M3	Lake_Baikal_phage	2.7e-14	38.6

DBSCAN-SWA_83

1118930 : 1121599

Pseudomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000613541.1\|1118930_1120145_-	PG:teichoic acid D-alanyltransferase DltB	A0A125RNP0	Pseudomonas_phage	8.5e-20	26.1
WP_164025994.1\|1120141_1121599_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9L3I8	Tupanvirus	5.8e-39	28.3

DBSCAN-SWA_84

1134721 : 1138245

environmental_halophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001006453.1\|1134721_1135972_-	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.8
WP_164026000.1\|1136077_1137385_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000168845.1\|1137483_1138245_-	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_85

1141732 : 1142758

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571218.1\|1141732_1142758_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-27	36.8

DBSCAN-SWA_86

1146131 : 1151308

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000589549.1\|1146131_1146488_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.7e-19	46.6
WP_001190695.1\|1146631_1146952_+	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	3.1e-06	36.4
WP_000422908.1\|1147101_1147641_-	nitroreductase	NA	NA	NA	NA
WP_000150013.1\|1147723_1148440_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	2.3e-17	30.6
WP_000974460.1\|1148587_1149010_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000569884.1\|1149408_1149903_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000255553.1\|1150057_1150675_+	amino acid transporter	NA	NA	NA	NA
WP_072353886.1\|1150747_1151308_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	2.2e-31	40.9

DBSCAN-SWA_87

1156232 : 1157476

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001059082.1\|1156232_1156433_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.4e-20	70.8
WP_001548082.1\|1156789_1157476_-	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	3.8e-33	54.2

DBSCAN-SWA_88

1166392 : 1175281

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000757406.1\|1166392_1167121_+	DUF5067 domain-containing protein	H9A0X8	Staphylococcus_phage	1.3e-18	37.5
WP_001057759.1\|1167312_1167459_+	hypothetical protein	NA	NA	NA	NA
WP_001058299.1\|1167474_1167798_+	hypothetical protein	NA	NA	NA	NA
WP_001085185.1\|1169119_1169584_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
WP_001050063.1\|1169605_1171978_-	ribonuclease R	Q0GXV6	Lactococcus_phage	5.1e-93	39.0
WP_001165962.1\|1172011_1172752_-	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_000556760.1\|1172867_1173101_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000785252.1\|1173167_1173626_-	hypothetical protein	NA	NA	NA	NA
WP_001121760.1\|1173976_1175281_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.7e-196	80.7

DBSCAN-SWA_89

1184399 : 1190219

Streptococcus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001049165.1\|1184399_1184987_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.2e-53	55.3
WP_000006551.1\|1185559_1186504_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.1e-54	40.6
WP_001248939.1\|1186614_1187610_-	YvcK family protein	A1IMD5	Streptococcus_phage	4.8e-53	41.9
WP_000369722.1\|1187606_1188518_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-08	36.1
WP_000134963.1\|1189283_1190219_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.9e-84	49.2

DBSCAN-SWA_90

1194622 : 1197469

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000662681.1\|1194622_1197469_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.1

DBSCAN-SWA_91

1200787 : 1201627

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000749383.1\|1200787_1201627_-	CHAP domain-containing protein	A0A2H4J675	uncultured_Caudovirales_phage	3.5e-12	42.2

DBSCAN-SWA_92

1207705 : 1213418

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026013.1\|1207705_1208788_-	DEAD/DEAH box helicase family protein	A0A1X9I5S6	Streptococcus_phage	1.3e-43	35.2
WP_164026014.1\|1209151_1210018_-	DegV family EDD domain-containing protein	NA	NA	NA	NA
WP_000192957.1\|1210161_1210803_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.1e-37	48.3
WP_000258151.1\|1210974_1212030_-	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_000460983.1\|1212347_1213418_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.3e-16	33.5

DBSCAN-SWA_93

1222697 : 1246259

uncultured_Caudovirales_phage(35.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000616842.1\|1222697_1223459_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6
WP_001245577.1\|1223455_1224412_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_164026017.1\|1224398_1225370_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.6e-138	78.6
WP_000499195.1\|1225408_1225564_-	hypothetical protein	NA	NA	NA	NA
WP_000562498.1\|1226077_1227049_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855505.1\|1227166_1229272_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000692521.1\|1229234_1229633_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_001068497.1\|1230433_1231300_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|1231319_1231820_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|1232160_1233666_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_031797439.1\|1233743_1233845_-	hypothetical protein	NA	NA	NA	NA
WP_000429006.1\|1233934_1234852_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_000197275.1\|1235531_1236074_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_164026020.1\|1236368_1237427_-	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	1.5e-20	27.3
WP_164026023.1\|1237666_1239181_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_164026025.1\|1239173_1240151_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	5.4e-25	33.3
WP_000983677.1\|1240372_1242154_-	DNA helicase RecQ	A0A2P1EM61	Moumouvirus	6.5e-77	37.0
WP_000525103.1\|1242165_1244049_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	6.7e-56	30.8
WP_000098285.1\|1244318_1246259_-	polyglycerol-phosphate lipoteichoic acid synthase LtaS	W6LM83	Streptococcus_phage	1.3e-110	39.5

DBSCAN-SWA_94

1249398 : 1259245

Pandoravirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217794.1\|1249398_1250550_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	3.5e-23	36.1
WP_000604515.1\|1250533_1251127_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_000446724.1\|1251477_1252146_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|1252147_1252567_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_164026027.1\|1252570_1253284_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	1.1e-51	43.5
WP_000637687.1\|1253382_1253967_+	hypothetical protein	NA	NA	NA	NA
WP_001093556.1\|1254246_1254687_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037807.1\|1255029_1255503_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|1255477_1256164_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244415.1\|1256163_1257219_+	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000702781.1\|1257290_1258274_-	glycosyltransferase family 2 protein	A0A192Y8W7	Salmonella_phage	1.5e-62	43.3
WP_000931237.1\|1258405_1259245_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.1e-56	42.3

DBSCAN-SWA_95

1270857 : 1272231

Powai_lake_megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000952032.1\|1270857_1272231_-	deoxyribodipyrimidine photo-lyase	A0A167RC11	Powai_lake_megavirus	1.6e-46	34.1

DBSCAN-SWA_96

1277208 : 1283488

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000857620.1\|1277208_1278882_-	amino acid ABC transporter ATP-binding/permease protein	W8CYL7	Bacillus_phage	3.4e-11	23.4
WP_000737159.1\|1278878_1280510_-	ABC transporter ATP-binding protein/permease	W5SAS9	Pithovirus	3.6e-13	29.2
WP_000469890.1\|1280728_1281604_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_000358498.1\|1281775_1282459_+	hypothetical protein	NA	NA	NA	NA
WP_000148828.1\|1282461_1282920_+	YaiI/YqxD family protein	NA	NA	NA	NA
WP_000820892.1\|1282921_1283488_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	6.1e-21	36.9

DBSCAN-SWA_97

1290686 : 1291160

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000833486.1\|1290686_1291160_-	cupin	A0A291AU44	Pandoravirus	1.6e-14	39.4

DBSCAN-SWA_98

1296422 : 1297220

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000731641.1\|1296422_1297220_+	LysM peptidoglycan-binding domain-containing protein	A0A223LD43	Bacillus_phage	9.3e-07	30.2

DBSCAN-SWA_99

1302052 : 1302814

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000985996.1\|1302052_1302814_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-33	34.8

DBSCAN-SWA_100

1307188 : 1308232

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001030771.1\|1307188_1308232_-	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	2.0e-17	26.6

DBSCAN-SWA_101

1314755 : 1315553

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001080809.1\|1314755_1315553_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-18	30.7

DBSCAN-SWA_102

1318778 : 1322737

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000817956.1\|1318778_1320506_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.7e-110	43.3
WP_000793075.1\|1320926_1322222_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	5.7e-14	26.6
WP_000832260.1\|1322338_1322737_-	glycerol-3-phosphate cytidylyltransferase	A0A222YWT0	Streptomyces_phage	3.2e-16	39.9

DBSCAN-SWA_103

1329671 : 1330415

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000894464.1\|1329671_1330415_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.2e-11	29.7

DBSCAN-SWA_104

1341566 : 1342127

Streptococcus_phage(100.0%)

integrase

attL 1335720:1335734|attR 1345715:1345729

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1335720:1335734	attL	NA	NA	NA	NA
WP_164026048.1\|1341566_1342127_-\|integrase	tyrosine-type recombinase/integrase	A0A141E172	Streptococcus_phage	1.3e-18	35.1
WP_164026048.1\|1341566_1342127_-\|integrase	tyrosine-type recombinase/integrase	A0A141E172	Streptococcus_phage	1.3e-18	35.1
1345715:1345729	attR	NA	NA	NA	NA

DBSCAN-SWA_105

1355078 : 1358432

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001200748.1\|1355078_1356089_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	5.6e-33	27.3
WP_001788287.1\|1356587_1357109_-	hypothetical protein	NA	NA	NA	NA
WP_000180230.1\|1357136_1358432_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	2.1e-24	27.9

DBSCAN-SWA_106

1371208 : 1372531

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000860587.1\|1371208_1372531_+	FAD-containing oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.4e-108	47.1

DBSCAN-SWA_107

1383835 : 1384492

Elephant_endotheliotropic_herpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000455256.1\|1383835_1384492_-	uracil-DNA glycosylase	U5U4C1	Elephant_endotheliotropic_herpesvirus	1.1e-45	46.4

DBSCAN-SWA_108

1388133 : 1391454

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001100835.1\|1388133_1389510_-	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.9e-21	24.5
WP_000347061.1\|1390053_1391454_-	MFS transporter	Q6JIH2	Burkholderia_virus	9.4e-55	32.8

DBSCAN-SWA_109

1410815 : 1411478

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026073.1\|1410815_1411478_+	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	4.1e-24	36.9

DBSCAN-SWA_110

1418058 : 1419246

Emiliania_huxleyi_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000250823.1\|1418058_1419246_-	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	4.4e-45	30.6

DBSCAN-SWA_111

1422274 : 1433228

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000090315.1\|1422274_1424356_-	elongation factor G	E4ZFJ7	Streptococcus_phage	2.7e-66	28.3
WP_001137495.1\|1424478_1424949_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_001142337.1\|1425014_1425428_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_000031892.1\|1425525_1425780_-	50S ribosomal protein L7ae-like protein	NA	NA	NA	NA
WP_001788197.1\|1425916_1429513_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	3.3e-67	24.6
WP_000918667.1\|1429676_1433228_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	2.1e-50	24.3

DBSCAN-SWA_112

1436912 : 1441695

Bacillus_virus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001288302.1\|1436912_1437461_-	transcription termination/antitermination protein NusG	G3MAW2	Bacillus_virus	8.6e-12	33.5
WP_001074473.1\|1437473_1437656_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_001788193.1\|1437711_1437855_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_000872874.1\|1437969_1438539_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_000664738.1\|1438619_1439144_-	NYN domain-containing protein	NA	NA	NA	NA
WP_000390332.1\|1439143_1439890_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000370182.1\|1439897_1440302_-	Mini-ribonuclease 3	NA	NA	NA	NA
WP_000631974.1\|1440294_1441695_-\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	1.5e-55	32.2

DBSCAN-SWA_113

1447705 : 1450162

Escherichia_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000897132.1\|1447705_1450162_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A1C3S747	Escherichia_phage	1.4e-133	41.2

DBSCAN-SWA_114

1469088 : 1479360

Catovirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001288202.1\|1469088_1470576_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.1e-92	41.1
WP_001790128.1\|1470628_1470721_-	hypothetical protein	NA	NA	NA	NA
WP_000613716.1\|1471114_1471591_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_001154302.1\|1471587_1471953_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_000167923.1\|1471930_1472734_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.9e-21	29.3
WP_000057594.1\|1472949_1473882_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	3.7e-108	65.7
WP_000148605.1\|1474060_1474942_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_001167888.1\|1475170_1477264_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	E5EQ50	Micromonas_sp._RCC1109_virus	4.0e-110	42.7
WP_000551283.1\|1477520_1478060_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	6.5e-12	29.8
WP_001176700.1\|1478064_1479360_-\|tRNA	tRNA lysidine(34) synthetase TilS	A0A1V0SI91	Klosneuvirus	8.2e-13	24.5

DBSCAN-SWA_115

1490137 : 1492602

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000933774.1\|1490137_1491103_-	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	6.1e-45	35.4
WP_001252529.1\|1491249_1492602_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L821	Tupanvirus	8.3e-24	30.4

DBSCAN-SWA_116

1498486 : 1501584

Klosneuvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001051129.1\|1498486_1500460_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.5e-93	36.2
WP_000279926.1\|1500744_1501584_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.7e-57	45.8

DBSCAN-SWA_117

1505490 : 1506108

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272126.1\|1505490_1506108_-	dTMP kinase	M1PSC7	Streptococcus_phage	9.2e-47	48.3

DBSCAN-SWA_118

1515158 : 1516856

Streptococcus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001109057.1\|1515158_1516856_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	2.5e-54	42.3

DBSCAN-SWA_119

1533507 : 1539747

Lactobacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001170268.1\|1533507_1534512_-	autolysin/adhesin Aaa	A0A0A7NU10	Lactobacillus_phage	3.6e-24	41.0
WP_000825526.1\|1534843_1535686_-	dipeptide ABC transporter glycylmethionine-binding lipoprotein	NA	NA	NA	NA
WP_000468001.1\|1535722_1536382_-	ABC transporter permease	NA	NA	NA	NA
WP_000569288.1\|1536385_1537411_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.2e-32	37.3
WP_001036664.1\|1537706_1538849_-	bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase	NA	NA	NA	NA
WP_000634094.1\|1538832_1539747_-	cysteine synthase family protein	A0A1W6JIM2	Lactococcus_phage	1.7e-49	39.9

DBSCAN-SWA_120

1566718 : 1569506

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000072586.1\|1566718_1567957_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.1e-130	63.4
WP_000028648.1\|1567949_1569506_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.6e-287	99.0

DBSCAN-SWA_121

1583279 : 1589091

Paenibacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000159785.1\|1583279_1583588_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	2.2e-12	51.9
WP_000041883.1\|1584312_1585017_+	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	2.6e-29	37.6
WP_000551776.1\|1585409_1585946_+	hypothetical protein	NA	NA	NA	NA
WP_000424963.1\|1586058_1587600_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000264071.1\|1587624_1589091_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5

DBSCAN-SWA_122

1597972 : 1599496

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026126.1\|1597972_1599496_+	alkyl hydroperoxide reductase subunit F	A0A249XZT7	Enterococcus_phage	4.2e-40	33.2

DBSCAN-SWA_123

1607068 : 1615485

Staphylococcus_phage(60.0%)

integrase

attL 1601550:1601563|attR 1610529:1610542

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1601550:1601563	attL	NA	NA	NA	NA
WP_000237576.1\|1607068_1607227_+\|integrase	integrase	Q4ZE80	Staphylococcus_phage	2.8e-08	64.4
WP_001817700.1\|1607653_1608592_+	Abi family protein	NA	NA	NA	NA
WP_000897044.1\|1608857_1609100_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_106669570.1\|1609151_1609655_-	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	1.6e-60	74.1
WP_001261460.1\|1609675_1609972_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_001052483.1\|1610215_1610407_+	hypothetical protein	U3PCX8	Staphylococcus_phage	4.9e-23	80.0
WP_001218732.1\|1610492_1611590_-	redox-regulated ATPase YchF	NA	NA	NA	NA
1610529:1610542	attR	NA	NA	NA	NA
WP_000157345.1\|1611601_1611805_-	DUF951 domain-containing protein	NA	NA	NA	NA
WP_001077602.1\|1611834_1612716_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_001566903.1\|1612872_1613718_-	ParB/RepB/Spo0J family partition protein	A0A1C9EHW0	Gordonia_phage	1.6e-12	34.4
WP_000655707.1\|1614381_1615485_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A0B5JD48	Pandoravirus	4.6e-12	29.0

DBSCAN-SWA_124

1625420 : 1626263

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000209549.1\|1625420_1626263_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.9e-11	27.2

DBSCAN-SWA_125

1647533 : 1650268

Bodo_saltans_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000280804.1\|1647533_1648556_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	1.1e-09	29.7
WP_001191953.1\|1648533_1649478_-	NAD-dependent deacetylase	NA	NA	NA	NA
WP_000449077.1\|1649467_1650268_-	protein-ADP-ribose hydrolase	A0A2K9L8X2	Tupanvirus	5.2e-42	43.9

DBSCAN-SWA_126

1668499 : 1669177

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000911017.1\|1668499_1669177_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-31	38.9

DBSCAN-SWA_127

1691271 : 1695711

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026139.1\|1691271_1695711_-	type VII secretion protein EssC	V5UPA0	Mycobacterium_phage	8.2e-28	24.3

DBSCAN-SWA_128

1708346 : 1710008

Amsacta_moorei_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026140.1\|1708346_1709006_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	9.9e-23	36.7
WP_000736795.1\|1709057_1710008_-	glycine-glycine endopeptidase LytM	V5R8R0	Arthrobacter_phage	1.5e-16	42.7

DBSCAN-SWA_129

1718394 : 1719831

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000164001.1\|1718394_1719831_-	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	3.7e-30	26.2

DBSCAN-SWA_130

1723591 : 1728130

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000925394.1\|1723591_1725331_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	1.5e-62	31.5
WP_164026145.1\|1725590_1726265_-	iron-sulfur cluster repair di-iron protein ScdA	NA	NA	NA	NA
WP_164026147.1\|1726408_1728130_-	glycosyltransferase	A0A1V0SAH6	Catovirus	2.1e-11	37.4

DBSCAN-SWA_131

1737457 : 1738501

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000645604.1\|1737457_1738501_-	galactitol-1-phosphate 5-dehydrogenase	E3SJ82	Synechococcus_phage	4.6e-14	24.6

DBSCAN-SWA_132

1745715 : 1747245

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000838210.1\|1745715_1747245_+	PTS transporter subunit EIIC	A0A2I7SAJ6	Vibrio_phage	2.4e-11	52.0

DBSCAN-SWA_133

1756120 : 1757626

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001008405.1\|1756120_1757626_+	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.0e-39	25.9

DBSCAN-SWA_134

1768907 : 1774266

Tetraselmis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000894660.1\|1768907_1771157_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.7e-186	45.1
WP_164026151.1\|1771744_1772713_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_000127990.1\|1772709_1774266_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	5.8e-13	27.2

DBSCAN-SWA_135

1784473 : 1786541

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000818913.1\|1784473_1785571_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.4e-24	35.6
WP_001815512.1\|1785953_1786541_-	M23 family metallopeptidase	A0A2K9VGT1	Pontimonas_phage	1.3e-13	40.1

DBSCAN-SWA_136

1795056 : 1798244

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000067358.1\|1795056_1796649_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.5e-21	33.2
WP_000794565.1\|1797158_1797356_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	2.1e-05	43.3
WP_000960712.1\|1797521_1798244_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-22	34.8

DBSCAN-SWA_137

1802115 : 1802796

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571407.1\|1802115_1802796_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.9e-33	37.0

DBSCAN-SWA_138

1819604 : 1820789

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001084434.1\|1819604_1820789_+	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	7.0e-35	29.2

DBSCAN-SWA_139

1825623 : 1835907

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076749343.1\|1825623_1832799_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	2.6e-68	29.4
WP_000826862.1\|1833245_1834496_-	MFS transporter	NA	NA	NA	NA
WP_000706137.1\|1834881_1835907_-	NAD-dependent formate dehydrogenase	A0A1V0SBV6	Catovirus	2.9e-29	33.9

DBSCAN-SWA_140

1839445 : 1842617

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000590860.1\|1839445_1840186_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-39	41.1
WP_000171919.1\|1840527_1841040_-	DUF4242 domain-containing protein	NA	NA	NA	NA
WP_000356963.1\|1841218_1841422_+	hypothetical protein	NA	NA	NA	NA
WP_001013481.1\|1841657_1842617_-	cation transporter	A0A1V0SED0	Indivirus	1.2e-11	34.2

DBSCAN-SWA_141

1845958 : 1848443

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026163.1\|1845958_1847104_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.6e-23	26.1
WP_000779494.1\|1847180_1848443_-	nucleotide sugar dehydrogenase	A0A127AXI2	Bacillus_phage	5.0e-23	25.8

DBSCAN-SWA_142

1855278 : 1861843

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000413171.1\|1855278_1856403_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SJE0	Klosneuvirus	6.7e-128	59.6
WP_001028282.1\|1856406_1857516_-	capsular polysaccharide biosynthesis protein CapF	NA	NA	NA	NA
WP_000459066.1\|1857528_1858557_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	2.0e-41	35.3
WP_164026165.1\|1858600_1860370_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.7e-29	31.3
WP_000565294.1\|1860389_1861154_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_000037328.1\|1861156_1861843_-	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	3.7e-28	36.1

DBSCAN-SWA_143

1865865 : 1867041

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000469831.1\|1865865_1867041_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	1.1e-29	27.6

DBSCAN-SWA_144

1872480 : 1873254

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000078092.1\|1872480_1873254_+	phosphonate ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-13	26.1

DBSCAN-SWA_145

1881288 : 1881888

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000874681.1\|1881288_1881888_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	7.6e-54	50.2

DBSCAN-SWA_146

1886825 : 1887806

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001793242.1\|1886825_1887806_-	NAD-dependent epimerase/dehydratase family protein	A0A1V0SAI6	Catovirus	1.0e-47	37.0

DBSCAN-SWA_147

1891176 : 1892379

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001223704.1\|1891176_1892379_-	staphyloferrin B biosynthesis decarboxylase SbnH	A0A2K9L4I2	Tupanvirus	1.1e-08	20.8

DBSCAN-SWA_148

1900645 : 1904855

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000570808.1\|1900645_1901626_-	2,3-diaminopropionate biosynthesis protein SbnA	A0A1W6JHY1	Lactococcus_phage	2.1e-40	35.6
WP_001045111.1\|1901856_1902849_+	staphyloferrin B ABC transporter substrate-binding protein SirA	NA	NA	NA	NA
WP_000924990.1\|1902864_1903860_+	staphyloferrin B ABC transporter permease subunit SirB	NA	NA	NA	NA
WP_000136636.1\|1903856_1904855_+	staphyloferrin B ABC transporter permease subunit SirC	A0A2H4IY97	uncultured_Caudovirales_phage	1.2e-14	27.5

DBSCAN-SWA_149

1936895 : 1937963

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000816128.1\|1936895_1937963_-	persulfide response sulfurtransferase CstA	A0A2H4PQR9	Staphylococcus_phage	3.5e-09	41.5

DBSCAN-SWA_150

1941187 : 1947036

Liberibacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024273384.1\|1941187_1944316_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	2.7e-70	30.9
WP_000394003.1\|1944299_1945532_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000190898.1\|1945521_1947036_-	SAM-dependent DNA methyltransferase	A0A2H4PQP4	Staphylococcus_phage	2.3e-46	29.8

DBSCAN-SWA_151

1952261 : 1962278

Bacillus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000088649.1\|1952261_1953062_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.0e-37	35.9
WP_001104177.1\|1953457_1954246_-	hypothetical protein	NA	NA	NA	NA
WP_001060140.1\|1954246_1955581_-	hypothetical protein	NA	NA	NA	NA
WP_000871607.1\|1955573_1957400_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.6e-30	31.3
WP_000101976.1\|1957412_1958114_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-42	39.2
WP_000095328.1\|1959316_1960600_-	adenylosuccinate synthase	L7Y4J5	Megavirus	1.8e-68	34.6
WP_164026176.1\|1960877_1962278_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	5.4e-111	48.1

DBSCAN-SWA_152

1968969 : 1978008

Bacillus_virus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000884334.1\|1968969_1970256_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.7e-88	51.2
WP_000177458.1\|1970634_1972149_-	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.5e-90	38.4
WP_000449218.1\|1972474_1973287_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_000819084.1\|1973373_1976037_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	2.7e-119	35.9
WP_000255578.1\|1976073_1978008_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	5.7e-143	44.9

DBSCAN-SWA_153

1988090 : 1994657

Faecalibacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000742837.1\|1988090_1988930_+	nucleoid occlusion protein	A0A2K9V477	Faecalibacterium_phage	2.2e-06	23.8
WP_000491382.1\|1989380_1989734_+	DUF3147 family protein	NA	NA	NA	NA
WP_000779136.1\|1989801_1990197_+	DUF3147 family protein	NA	NA	NA	NA
WP_001054118.1\|1990456_1991026_+	helix-turn-helix domain-containing protein	D2XQ11	Bacillus_virus	6.2e-05	33.3
WP_001059079.1\|1991151_1991352_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.4e-19	69.8
WP_000672039.1\|1991744_1991936_-	peptide resistance ABC transporter activity modulator VraH	NA	NA	NA	NA
WP_000143652.1\|1992028_1993909_-	peptide resistance ABC transporter permease subunit VraE	NA	NA	NA	NA
WP_000154162.1\|1993898_1994657_-	peptide resistance ABC transporter ATP-binding subunit VraD	G9BWD6	Planktothrix_phage	9.0e-36	39.5

DBSCAN-SWA_154

2007962 : 2009675

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000138656.1\|2007962_2009675_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-20	32.3

DBSCAN-SWA_155

2015303 : 2016317

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026180.1\|2015303_2016317_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X7QHI1	Faustovirus	2.1e-08	22.2

DBSCAN-SWA_156

2028815 : 2029508

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026184.1\|2028815_2029508_+	polysaccharide biosynthesis tyrosine autokinase	A0A1X9I5D6	Streptococcus_phage	5.7e-29	38.5

DBSCAN-SWA_157

2055621 : 2057481

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001125609.1\|2055621_2057481_-	amidase domain-containing protein	A0A249Y0X5	Enterococcus_phage	9.7e-15	37.3

DBSCAN-SWA_158

2082915 : 2084666

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000143426.1\|2082915_2083803_+	sensor histidine kinase	Q8QNA2	Ectocarpus_siliculosus_virus	3.3e-05	22.5
WP_164026217.1\|2083910_2084666_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.9e-30	37.4

DBSCAN-SWA_159

2088086 : 2088584

Canarypox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001065268.1\|2088086_2088584_+	glutathione peroxidase	Q6VZR0	Canarypox_virus	1.8e-21	33.1

DBSCAN-SWA_160

2093635 : 2096019

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001071713.1\|2093635_2095486_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.1e-235	64.3
WP_000173331.1\|2095482_2096019_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	3.9e-41	48.0

DBSCAN-SWA_161

2101864 : 2111978

Klosneuvirus(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000066516.1\|2101864_2103574_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	2.2e-58	32.3
WP_000011688.1\|2103851_2104064_+	hypothetical protein	NA	NA	NA	NA
WP_001028786.1\|2104343_2104787_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_001172348.1\|2104980_2106579_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	6.9e-78	36.8
WP_001791980.1\|2106638_2106968_-	hypothetical protein	NA	NA	NA	NA
WP_164026223.1\|2107263_2108760_+	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_001031400.1\|2108953_2109844_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	7.2e-08	29.2
WP_001237629.1\|2109966_2110383_-	hypothetical protein	NA	NA	NA	NA
WP_000030064.1\|2110640_2111978_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	3.0e-18	26.7

DBSCAN-SWA_162

2141279 : 2145067

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000751267.1\|2141279_2141981_+	lytic transglycosylase IsaA	Q4Z8Z7	Staphylococcus_phage	4.0e-38	46.4
WP_000996736.1\|2142256_2142745_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000379821.1\|2143255_2145067_+	acetyltransferase	A0A1R3Y5Q6	Salmonella_virus	1.3e-35	31.5

DBSCAN-SWA_163

2153500 : 2157621

Acanthocystis_turfacea_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161366.1\|2153500_2154499_+	D-lactate dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	2.6e-35	30.2
WP_000076661.1\|2154588_2154795_-	copper chaperone CopZ	NA	NA	NA	NA
WP_164026241.1\|2155212_2157621_-	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.2e-127	41.0

DBSCAN-SWA_164

2166855 : 2169891

Enterobacteria_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001058988.1\|2166855_2168961_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	3.1e-118	38.5
WP_000455994.1\|2169369_2169891_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	9.0e-27	42.3

DBSCAN-SWA_165

2176314 : 2182684

Yellowstone_lake_phycodnavirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026250.1\|2176314_2178054_+	pyruvate oxidase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.0e-34	24.1
WP_000473680.1\|2178354_2180421_+	PTS transporter subunit EIIC	A0A2I7SAJ6	Vibrio_phage	8.3e-07	43.3
WP_000206033.1\|2180786_2181197_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_000240662.1\|2181238_2181583_+	thioredoxin family protein	NA	NA	NA	NA
WP_001228169.1\|2181715_2182684_+	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	5.2e-12	26.5

DBSCAN-SWA_166

2192399 : 2193392

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161536.1\|2192399_2193392_-	D-lactate dehydrogenase	M1HYB0	Acanthocystis_turfacea_Chlorella_virus	1.1e-36	31.5

DBSCAN-SWA_167

2202672 : 2203368

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000382899.1\|2202672_2203368_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	4.7e-39	38.9

DBSCAN-SWA_168

2224261 : 2225128

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026268.1\|2224261_2225128_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	3.7e-78	52.6

DBSCAN-SWA_169

2234080 : 2239276

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076079486.1\|2234080_2235889_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.3e-93	37.7
WP_164026272.1\|2236020_2236413_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_000088720.1\|2236414_2239276_+	DUF3427 domain-containing protein	Q5YA94	Bacillus_phage	2.4e-28	27.9

DBSCAN-SWA_170

2243868 : 2244564

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000217471.1\|2243868_2244564_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.3e-09	37.5

DBSCAN-SWA_171

2247992 : 2248811

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000824941.1\|2247992_2248811_+	SDR family oxidoreductase	A0A2P1ELN2	Moumouvirus	5.0e-08	27.7

DBSCAN-SWA_172

2256690 : 2258248

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000173875.1\|2256690_2257506_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-14	29.8
WP_000590512.1\|2257498_2258248_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.1e-20	30.8

DBSCAN-SWA_173

2265366 : 2269795

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000923523.1\|2265366_2266029_+	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	4.2e-21	30.8
WP_000072147.1\|2266021_2266798_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_164026282.1\|2267193_2268381_+	MFS transporter	NA	NA	NA	NA
WP_000700926.1\|2268442_2269795_-	carboxylesterase/lipase family protein	A0A0B5J865	Pandoravirus	2.8e-11	33.3

DBSCAN-SWA_174

2273482 : 2275341

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000948979.1\|2273482_2274709_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
WP_000569120.1\|2274705_2275341_+	ABC transporter permease	G3M9Y4	Bacillus_virus	9.0e-05	26.2

DBSCAN-SWA_175

2293067 : 2299320

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001176863.1\|2293067_2294210_-	glycerate kinase	W6LM47	Streptococcus_phage	5.3e-56	44.3
WP_000779360.1\|2294467_2294854_+	GtrA family protein	NA	NA	NA	NA
WP_000482647.1\|2294987_2295095_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_001064814.1\|2295798_2297562_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.5e-36	24.7
WP_000486494.1\|2297586_2299320_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.0e-31	25.7

DBSCAN-SWA_176

2302781 : 2308552

Staphylococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000971550.1\|2302781_2303897_+	pyridoxal phosphate-dependent aminotransferase family protein	V5LQ39	Emiliania_huxleyi_virus	1.6e-20	24.7
WP_000286877.1\|2303907_2304600_+	6-carboxyhexanoate--CoA ligase	NA	NA	NA	NA
WP_000200948.1\|2304610_2305078_+	QueT transporter family protein	NA	NA	NA	NA
WP_164026290.1\|2305129_2306107_-	beta-channel forming cytolysin	A0A2H4PQH7	Staphylococcus_phage	4.6e-141	75.9
WP_164026292.1\|2306108_2307056_-	beta-channel forming cytolysin	A0A2I6PER8	Staphylococcus_phage	2.1e-138	77.1
WP_000594519.1\|2307622_2308552_-	bi-component gamma-hemolysin HlgAB subunit A	A0A2H4PQI5	Staphylococcus_phage	3.2e-120	71.1

DBSCAN-SWA_177

2316498 : 2317230

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000615461.1\|2316498_2317230_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.1e-25	34.7

DBSCAN-SWA_178

2335415 : 2336975

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000692645.1\|2335415_2336975_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	4.4e-21	46.8

DBSCAN-SWA_179

2356365 : 2357400

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000655972.1\|2356365_2357400_+	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	5.8e-17	26.6

DBSCAN-SWA_180

2367260 : 2371157

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000477328.1\|2367260_2368634_-	heme sensor histidine kinase HssS	A0A1V0SGX0	Hokovirus	1.3e-13	29.8
WP_000249497.1\|2368626_2369301_-	DNA-binding heme response regulator HssR	W8CYM9	Bacillus_phage	3.6e-52	45.2
WP_000761411.1\|2369436_2370492_+	ABC transporter permease	NA	NA	NA	NA
WP_001229911.1\|2370491_2371157_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-36	38.8

DBSCAN-SWA_181

2374896 : 2376105

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000999168.1\|2374896_2376105_+	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	4.6e-34	26.4

DBSCAN-SWA_182

2388226 : 2389126

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000524831.1\|2388226_2389126_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.2e-15	28.7

DBSCAN-SWA_183

2401945 : 2402827

Diadromus_pulchellus_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000730034.1\|2401945_2402827_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.8e-62	45.9

DBSCAN-SWA_184

2410705 : 2411341

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000285450.1\|2410705_2411341_+	HAD family hydrolase	A7J6N1	Paramecium_bursaria_Chlorella_virus	1.6e-09	27.1

DBSCAN-SWA_185

2424906 : 2429301

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011447058.1\|2424906_2425545_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JQU5	Staphylococcus_phage	2.6e-36	48.1
WP_000684141.1\|2426269_2427394_+	NAD(P)-binding protein	A0A2K9L3K5	Tupanvirus	5.5e-13	22.8
WP_000417016.1\|2427485_2428439_-	2-hydroxyacid dehydrogenase	A0A1V0SBV6	Catovirus	2.9e-31	28.9
WP_000737705.1\|2428800_2429301_-	CHAP domain-containing protein	A0A2R3ZXQ4	Staphylococcus_phage	2.0e-07	39.3

DBSCAN-SWA_186

2433217 : 2434021

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000717381.1\|2433217_2434021_-	CHAP domain-containing protein	A0A2R3ZXQ4	Staphylococcus_phage	9.3e-07	41.3

DBSCAN-SWA_187

2452997 : 2453603

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024273547.1\|2452997_2453603_+	ATP-binding cassette domain-containing protein	W5SAS9	Pithovirus	6.6e-13	30.1

DBSCAN-SWA_188

2465685 : 2468853

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026351.1\|2465685_2468853_+	MMPL family transporter	S5VTK5	Leptospira_phage	8.1e-62	21.8

DBSCAN-SWA_189

2494290 : 2495957

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000389652.1\|2494290_2495100_+	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	3.3e-20	29.5
WP_000155385.1\|2495096_2495957_+	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	9.7e-10	23.9

DBSCAN-SWA_190

2499557 : 2501222

Yellowstone_lake_phycodnavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000130155.1\|2499557_2501222_+	acetolactate synthase AlsS	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.6e-45	25.6

DBSCAN-SWA_191

2506304 : 2507153

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001015500.1\|2506304_2507153_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.0e-44	39.2

DBSCAN-SWA_192

2510183 : 2510924

Orpheovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024273263.1\|2510183_2510924_-	NAD-dependent protein deacylase	A0A2I2L319	Orpheovirus	1.5e-14	30.8

DBSCAN-SWA_193

2517245 : 2518658

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000169224.1\|2517245_2518658_+	6-phospho-beta-galactosidase	A0A0B5JD41	Pandoravirus	3.0e-48	28.9

DBSCAN-SWA_194

2522624 : 2524187

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000792338.1\|2522624_2524187_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.6e-18	24.8

DBSCAN-SWA_195

2534389 : 2535358

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026369.1\|2534389_2535358_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	3.0e-15	28.9

DBSCAN-SWA_196

2551182 : 2552091

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167867.1\|2551182_2552091_+	arginase	A0A1V0SJM8	Klosneuvirus	3.2e-27	32.0

DBSCAN-SWA_197

2555682 : 2563104

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026373.1\|2555682_2563104_+	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	2.5e-21	37.9

DBSCAN-SWA_198

2569360 : 2572180

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026378.1\|2569360_2571166_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	8.9e-98	38.4
WP_000908182.1\|2571397_2572180_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.3e-09	30.1

DBSCAN-SWA_199

2585185 : 2589018

Clostridium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000070866.1\|2585185_2585629_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	5.6e-38	53.7
WP_000160304.1\|2585749_2586460_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_001083324.1\|2586774_2587437_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_001242311.1\|2587716_2589018_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.6e-133	58.9

DBSCAN-SWA_200

2596956 : 2598567

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000159960.1\|2596956_2598567_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.7e-146	49.6

DBSCAN-SWA_201

2606370 : 2614120

Bacillus_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000273356.1\|2606370_2606970_+	thymidine kinase	G3MBK1	Bacillus_virus	6.2e-32	42.9
WP_000460242.1\|2606970_2608047_+	peptide chain release factor 1	NA	NA	NA	NA
WP_000248733.1\|2608033_2608870_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_072362259.1\|2608902_2610000_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	3.6e-41	35.6
WP_000697334.1\|2609996_2610416_+	low molecular weight protein arginine phosphatase	NA	NA	NA	NA
WP_000654185.1\|2610522_2611047_+	TIGR01440 family protein	NA	NA	NA	NA
WP_000120494.1\|2611073_2612312_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	8.2e-103	53.0
WP_000048712.1\|2612339_2612969_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_164026384.1\|2612992_2614120_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	6.0e-28	29.9

DBSCAN-SWA_202

2624523 : 2624919

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000932694.1\|2624523_2624919_+	single-stranded DNA-binding protein	A0A1J0MFK5	Staphylococcus_phage	1.3e-14	38.5

DBSCAN-SWA_203

2631020 : 2631668

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026391.1\|2631020_2631668_-	HD domain-containing protein	H2ED17	Moumouvirus	1.0e-08	26.6

DBSCAN-SWA_204

2638868 : 2640389

Diachasmimorpha_longicaudata_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164026393.1\|2638868_2640389_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.0e-58	33.9

DBSCAN-SWA_205

2646073 : 2648101

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000546597.1\|2646073_2648101_+	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	2.3e-25	23.5

DBSCAN-SWA_206

2653251 : 2656636

Clostridium_botulinum_C_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000621175.1\|2653251_2653614_+	type II toxin-antitoxin system PemK/MazF family toxin	Q332J9	Clostridium_botulinum_C_phage	4.2e-07	32.8
WP_000390829.1\|2653963_2654965_+	PP2C family protein-serine/threonine phosphatase	NA	NA	NA	NA
WP_001052491.1\|2655083_2655410_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_164026401.1\|2655381_2655891_+	anti-sigma B factor RsbW	NA	NA	NA	NA
WP_001041102.1\|2655865_2656636_+	RNA polymerase sigma factor SigB	A0A0A0RNH9	Bacillus_phage	1.3e-21	34.9

DBSCAN-SWA_207

2665843 : 2717038

Staphylococcus_phage(44.0%)

protease,integrase,coat,tRNA,terminase,transposase

attL 2704407:2704426|attR 2720068:2720087

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001808146.1\|2665843_2667163_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000688533.1\|2667564_2667981_+	hypothetical protein	NA	NA	NA	NA
WP_000216855.1\|2668057_2669326_-	threonine ammonia-lyase IlvA	NA	NA	NA	NA
WP_164026405.1\|2669340_2669913_-	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_000531820.1\|2669913_2671284_-	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_000221946.1\|2671297_2672344_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_000094576.1\|2672346_2673876_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	5.5e-08	28.1
WP_072399972.1\|2673905_2674925_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_000196911.1\|2675046_2675301_-	ACT domain-containing protein	NA	NA	NA	NA
WP_000047820.1\|2675300_2677070_-	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	5.3e-63	30.1
WP_001255780.1\|2677097_2678786_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_001789600.1\|2679103_2679259_-	hypothetical protein	NA	NA	NA	NA
WP_072433195.1\|2679323_2679758_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_001086742.1\|2679738_2680401_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000372758.1\|2680373_2680838_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000159053.1\|2680830_2681856_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	5.8e-62	40.6
WP_000106329.1\|2681957_2683568_-	MutS family DNA mismatch repair protein	A0A0N9R0S5	Chrysochromulina_ericina_virus	3.3e-19	26.9
WP_001792272.1\|2684248_2684377_+	hypothetical protein	NA	NA	NA	NA
WP_164026407.1\|2684521_2686450_-	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	2.4e-53	30.4
WP_001283612.1\|2686702_2687338_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_164026505.1\|2687692_2688721_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_000581077.1\|2688780_2689005_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_001052257.1\|2689211_2690462_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	3.4e-40	31.2
WP_000790324.1\|2690644_2691595_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_000141426.1\|2691743_2693228_+	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	4.0e-19	25.6
WP_001253302.1\|2693224_2694184_+	carbohydrate kinase	NA	NA	NA	NA
WP_000688498.1\|2694552_2695269_-	response regulator transcription factor	A0A2H4J4Z6	uncultured_Caudovirales_phage	3.0e-25	32.6
WP_164026507.1\|2695287_2696532_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_001093929.1\|2696604_2696745_-	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_164026409.1\|2696741_2697311_-	accessory gene regulator AgrB	NA	NA	NA	NA
WP_001549197.1\|2697546_2697681_+	delta-lysin family phenol-soluble modulin	NA	NA	NA	NA
WP_000867940.1\|2698276_2699062_-	carbon-nitrogen family hydrolase	NA	NA	NA	NA
WP_000522384.1\|2699422_2700049_-	nitroreductase family protein	NA	NA	NA	NA
WP_164026410.1\|2700245_2701505_+	hypothetical protein	NA	NA	NA	NA
WP_000197635.1\|2701529_2702273_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_164026412.1\|2702447_2702732_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	45.2
WP_000240645.1\|2702807_2704424_+	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
2704407:2704426	attL	NA	NA	NA	NA
WP_000179345.1\|2704492_2705665_-\|integrase	site-specific integrase	A0A1W6JQD3	Staphylococcus_phage	3.5e-220	98.2
WP_000620857.1\|2705678_2706353_-	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_000153640.1\|2706525_2706744_+	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000481967.1\|2706748_2707066_+	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000708433.1\|2707062_2707218_+	hypothetical protein	NA	NA	NA	NA
WP_001231376.1\|2707202_2707406_+	hypothetical protein	A0A1W6JQF4	Staphylococcus_phage	2.0e-30	98.5
WP_162675796.1\|2707407_2707791_+	pathogenicity island protein	A0A1W6JQI7	Staphylococcus_phage	3.1e-61	95.3
WP_164026414.1\|2707791_2708106_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	3.2e-19	57.0
WP_164026416.1\|2708176_2710429_+	DNA primase	A0A2H4JCU9	uncultured_Caudovirales_phage	0.0e+00	72.7
WP_000567972.1\|2710699_2711044_+	hypothetical protein	A0A2H4JHE6	uncultured_Caudovirales_phage	5.2e-39	73.5
WP_164026418.1\|2711045_2711687_+	pathogenicity island protein	Q4ZE67	Staphylococcus_phage	5.7e-108	91.5
WP_164026420.1\|2711985_2712327_+	pathogenicity island protein	Q4ZE66	Staphylococcus_phage	4.2e-57	98.2
WP_162675849.1\|2712357_2713011_+	hypothetical protein	Q4ZE82	Staphylococcus_phage	2.9e-115	98.6
WP_164026422.1\|2713063_2713591_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	5.4e-88	95.4
WP_162675847.1\|2713722_2713935_+	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	2.1e-27	85.7
WP_024273585.1\|2713931_2714501_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	3.9e-100	97.4
WP_164026425.1\|2714684_2716154_+	MFS transporter	NA	NA	NA	NA
WP_000879843.1\|2716354_2717038_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
2720068:2720087	attR	NA	NA	NA	NA

DBSCAN-SWA_208

2720794 : 2721421

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000216894.1\|2720794_2721421_+	hypothetical protein	C8CH40	Staphylococcus_phage	7.0e-42	44.5

DBSCAN-SWA_209

2727308 : 2751794

Staphylococcus_phage(73.81%)

integrase,terminase

attL 2716338:2716354|attR 2752090:2752106

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2716338:2716354	attL	NA	NA	NA	NA
WP_164026427.1\|2727308_2728361_+	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.5e-36	34.6
WP_000595401.1\|2728382_2729399_+	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_164026429.1\|2730517_2731555_-\|integrase	tyrosine-type recombinase/integrase	Q4ZCY6	Staphylococcus_virus	8.8e-175	97.4
WP_098692184.1\|2731621_2731975_-	DUF1640 domain-containing protein	Q4ZCY5	Staphylococcus_virus	2.7e-11	96.6
WP_098692171.1\|2732075_2732555_-	hypothetical protein	NA	NA	NA	NA
WP_164026451.1\|2732586_2733051_-	toxin	A0A2I6PEK4	Staphylococcus_phage	2.1e-83	97.4
WP_000429766.1\|2733063_2733393_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_001115060.1\|2733553_2733745_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_001001356.1\|2733828_2734005_+	hypothetical protein	A0A2I6PEL1	Staphylococcus_phage	8.8e-27	100.0
WP_000549549.1\|2734001_2734232_-	hypothetical protein	A0A2I6PE22	Staphylococcus_phage	1.8e-35	97.4
WP_095316866.1\|2734288_2734486_+	hypothetical protein	A7TWF5	Staphylococcus_phage	6.6e-23	95.4
WP_095321183.1\|2734472_2734853_-	DUF2513 domain-containing protein	Q4ZCQ5	Staphylococcus_virus	2.9e-67	98.4
WP_098692166.1\|2734908_2735127_+	DUF2829 domain-containing protein	A0A0H3U4C7	Staphylococcus_phage	2.8e-14	55.6
WP_098692165.1\|2735115_2735445_-	hypothetical protein	M9NS98	Staphylococcus_phage	1.4e-30	60.6
WP_098692183.1\|2735504_2735825_+	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	2.1e-55	97.2
WP_001285948.1\|2735821_2735983_+	DUF1270 domain-containing protein	A9CR58	Staphylococcus_phage	1.1e-20	98.1
WP_000174994.1\|2736061_2736385_+	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_000985976.1\|2736399_2736762_+	hypothetical protein	A0A2I6PF03	Staphylococcus_phage	4.9e-56	100.0
WP_107378073.1\|2736758_2737925_+	DUF2800 domain-containing protein	A7TWG4	Staphylococcus_phage	7.7e-220	99.2
WP_164026454.1\|2737951_2738506_+	DUF2815 family protein	M9QRS1	Staphylococcus_phage	7.2e-99	99.5
WP_164026456.1\|2738574_2740527_+	DNA polymerase	B7T0G8	Staphylococcus_virus	0.0e+00	98.6
WP_001164628.1\|2740539_2740725_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	2.1e-26	98.4
WP_042909074.1\|2740724_2741126_+	phage DNA polymerase	A0A2I6PEL5	Staphylococcus_phage	4.7e-68	99.2
WP_164026458.1\|2741125_2741383_+	DUF3310 domain-containing protein	A0A1X9H067	Staphylococcus_phage	1.7e-42	98.8
WP_015994746.1\|2741385_2741586_+	hypothetical protein	B7T0H2	Staphylococcus_virus	3.7e-29	100.0
WP_015994747.1\|2741582_2742272_+	N-6 DNA methylase	B7T0H3	Staphylococcus_virus	6.1e-132	100.0
WP_103213508.1\|2742285_2742492_+	hypothetical protein	B7T0H4	Staphylococcus_virus	5.1e-34	98.5
WP_000983952.1\|2742920_2743115_+	hypothetical protein	B7T0H6	Staphylococcus_virus	2.4e-25	92.2
WP_164026460.1\|2743111_2743549_+	hypothetical protein	NA	NA	NA	NA
WP_164026462.1\|2743545_2743830_+	hypothetical protein	Q9MBR2	Staphylococcus_prophage	7.0e-42	91.5
WP_162637865.1\|2743822_2744077_+	DUF1024 family protein	A0A0H4IP74	Staphylococcus_phage	4.6e-37	97.6
WP_162637864.1\|2744063_2744306_+	hypothetical protein	A0A2H4JHI8	uncultured_Caudovirales_phage	5.2e-30	85.0
WP_164026464.1\|2744298_2744835_+	dUTPase	A0A1P8L6E0	Staphylococcus_phage	1.0e-94	99.4
WP_164026466.1\|2745110_2745329_+	DUF1381 domain-containing protein	A0A2I6PDB6	Staphylococcus_phage	2.0e-25	95.3
WP_117219955.1\|2745312_2745549_+	hypothetical protein	Q4ZA37	Staphylococcus_virus	9.6e-37	97.4
WP_000595260.1\|2745541_2745694_+	transcriptional activator RinB	A7TWI2	Staphylococcus_phage	2.6e-19	100.0
WP_000265258.1\|2745761_2745962_+	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_094978771.1\|2747405_2748461_+	hypothetical protein	A0A0K1LKN1	Staphylococcus_phage	3.6e-208	100.0
WP_001801650.1\|2748569_2748668_-	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	3.7e-11	100.0
WP_000665203.1\|2748801_2749092_+	VRR-NUC domain-containing protein	A0A2I6PEN7	Staphylococcus_phage	6.5e-51	100.0
WP_001793488.1\|2749072_2750440_+	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	1.7e-263	100.0
WP_000528512.1\|2750452_2750890_+	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_031867793.1\|2751046_2751361_+	HNH endonuclease	A0A2I6PF37	Staphylococcus_phage	3.2e-56	99.0
WP_000778933.1\|2751488_2751794_+\|terminase	terminase	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
2752090:2752106	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_CP048431.1|WP_031797439.1|1233743_1233845_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP048431.1|WP_031797439.1|1233743_1233845_-|hypothetical-protein

1233743_1233845_-

33 aa aa

1222697-1246259

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP048431_3	Orphan	3.1\|875160\|37\|NZ_CP048431\|CRT	875160-875196	37	1235359-1235395	0

1. spacer 3.1|875160|37|NZ_CP048431|CRT matches to NZ_CP048431 position: 1235359-1235395, mismatch: 0

aacttgcattgtctgtagaaattgggaatccaatttc	CRISPR spacer
aacttgcattgtctgtagaaattgggaatccaatttc	Protospacer
*************************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP048431

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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