CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_CP049317	Caballeronia sp. SBC2 plasmid pSBC2-1, complete sequence	0 crisprs	RT,csa3	0	0	1
NZ_CP049323	Caballeronia sp. SBC2 plasmid pSBC2-7, complete sequence	0 crisprs	NA	0	0	3
NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	0 crisprs	csa3,WYL,RT	0	0	2
NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	1 crisprs	NA	0	3	2
NZ_CP049322	Caballeronia sp. SBC2 plasmid pSBC2-6, complete sequence	0 crisprs	RT	0	0	0
NZ_CP049319	Caballeronia sp. SBC2 plasmid pSBC2-3, complete sequence	0 crisprs	csa3,RT	0	0	5
NZ_CP049316	Caballeronia sp. SBC2 chromosome, complete genome	3 crisprs	cas2,cas1,cas4,cas7,cas8c,cas5,cas3,RT,WYL,DEDDh,DinG,csa3	1	12	2
NZ_CP049321	Caballeronia sp. SBC2 plasmid pSBC2-5, complete sequence	0 crisprs	WYL,csx1,PD-DExK	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

926058 : 934131

Burkholderia_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165096763.1\|926058_927141_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.7e-17	27.3
WP_165096766.1\|927128_927833_+	response regulator	A0A2R2ZGH8	Clostridioides_phage	4.1e-06	21.8
WP_165096769.1\|927942_928896_+	sterol desaturase family protein	NA	NA	NA	NA
WP_165096773.1\|928853_929750_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_165096777.1\|929875_930619_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.9e-15	31.7
WP_165101392.1\|931277_931706_+	hypothetical protein	NA	NA	NA	NA
WP_165096781.1\|931881_932217_-	type II toxin-antitoxin system HicB family antitoxin	R4JJS9	Burkholderia_phage	1.1e-38	70.6
WP_165096786.1\|932213_932468_-	type II toxin-antitoxin system HicA family toxin	R4JMD3	Burkholderia_phage	1.2e-29	71.4
WP_165101395.1\|932586_934131_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.1e-10	33.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP049323

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6219

Ochrobactrum_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165105635.1\|391_1168_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.1e-31	36.5
WP_165108215.1\|3012_3990_-	TrfA family protein	NA	NA	NA	NA
WP_165108217.1\|4075_5245_+	AAA family ATPase	A0A240F4U1	Ochrobactrum_phage	6.7e-30	25.9
WP_165108219.1\|5259_6219_+	ParB/RepB/Spo0J family partition protein	A0A240F4U0	Ochrobactrum_phage	4.2e-06	27.3

DBSCAN-SWA_2

11888 : 14421

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165108231.1\|11888_12164_+	HU family DNA-binding protein	A4JWM7	Burkholderia_virus	9.9e-17	55.1
WP_165108208.1\|12241_12460_-	hypothetical protein	NA	NA	NA	NA
WP_165108259.1\|12501_12894_-	hypothetical protein	NA	NA	NA	NA
WP_165108233.1\|13503_14421_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.3e-16	34.1

DBSCAN-SWA_3

20602 : 21505

Diadromus_pulchellus_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165108249.1\|20602_21505_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	1.8e-75	52.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP049320

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049320_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049320_1

49708-49967

Orphan

Consensus_repeat	Method
GAAGGTGAGGTTAATTGTGCA	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP049320_1

>merge|NZ_CP049320|1|49708-49967|PILER-CR
GATGGTGAGGTTAGTTGTGCAGTGATGGGAAAAGAGACCGGTACGGAGGATGGCGAGCAAAATTCATGGTGAGGTCGATTGTGCATTGCATCACCGCTGGTCCGTGCTCGCGGGTTTTTCCACTAAAAATATATTAGGGAACGTCCAAAACACGCGATTGAAGGTGAGGTTAATTGTGCAGATTTACGCTTTGGCCTTTTTGCGGAGATTTTTCGCGCTTGTTCCGGAAATCCGGGTACGAAGGTGAGGTTGATTGTGCA

>NZ_CP049320|1|1|49708-49967|PILER-CR
GATGGTGAGGTTAGTTGTGCA	GTGATGGGAAAAGAGACCGGTACGGAGGATGGCGAGCAAAATT
CATGGTGAGGTCGATTGTGCA	TTGCATCACCGCTGGTCCGTGCTCGCGGGTTTTTCCACTAAAAATATATTAGGGAACGTCCAAAACACGCGATT
GAAGGTGAGGTTAATTGTGCA	GATTTACGCTTTGGCCTTTTTGCGGAGATTTTTCGCGCTTGTTCCGGAAATCCGGGTAC
GAAGGTGAGGTTGATTGTGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049320.1\|WP_165106819.1\|34856_36056_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP049320.1\|WP_165106831.1\|41869_42787_+\|5-dehydro-4-deoxyglucarate-dehydratase	unknown	unknown	gnl\|CDD\|235141
NZ_CP049320.1\|WP_165107445.1\|43000_44356_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|273326
NZ_CP049320.1\|WP_165106836.1\|46019_46484_+\|type-II-secretion-system-major-pseudopilin-GspG	unknown	unknown	gnl\|CDD\|377975
NZ_CP049320.1\|WP_165106877.1\|62293_62560_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049320.1\|WP_165107447.1\|58160_59303_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380565
NZ_CP049320.1\|WP_165106842.1\|47797_49201_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NZ_CP049320.1\|WP_165106875.1\|61243_61987_+\|acetoacetyl-CoA-reductase	unknown	unknown	gnl\|CDD\|273823
NZ_CP049320.1\|WP_165106864.1\|59568_59874_+\|panthothenate-synthetase	unknown	unknown	unknown
NZ_CP049320.1\|WP_165106855.1\|56020_56998_+\|agmatinase	unknown	unknown	gnl\|CDD\|212537
NZ_CP049320.1\|WP_165106879.1\|62748_63003_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049320.1\|WP_165106824.1\|37487_38015_-\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NZ_CP049320.1\|WP_165106828.1\|40077_41667_-\|galactarate-dehydratase	unknown	unknown	gnl\|CDD\|274491
NZ_CP049320.1\|WP_165106848.1\|51478_52456_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|319251
NZ_CP049320.1\|WP_165106852.1\|54003_54504_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|307151
NZ_CP049320.1\|WP_165106826.1\|38142_39135_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270389
NZ_CP049320.1\|WP_165106839.1\|46569_47343_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP049320.1\|WP_165106822.1\|36132_37485_-\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NZ_CP049320.1\|WP_165106845.1\|50270_51482_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274585
NZ_CP049320.1\|WP_165106861.1\|56998_57934_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656

Protein	Function_ID	Function_description	E-value
NZ_CP049320.1\|WP_165106819.1\|34856_36056_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	7.94271e-74
NZ_CP049320.1\|WP_165106831.1\|41869_42787_+\|5-dehydro-4-deoxyglucarate-dehydratase	gnl\|CDD\|235141	PRK03620, PRK03620, 5-dehydro-4-deoxyglucarate dehydratase; Provisional.	0
NZ_CP049320.1\|WP_165107445.1\|43000_44356_+\|MFS-transporter	gnl\|CDD\|273326	TIGR00893, Probable_glucarate_transporter, D-galactonate transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	9.9261e-140
NZ_CP049320.1\|WP_165106836.1\|46019_46484_+\|type-II-secretion-system-major-pseudopilin-GspG	gnl\|CDD\|377975	pfam08334, T2SSG, Type II secretion system (T2SS), protein G. The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. The T2SG family includes proteins such as EpsG (P45773) in Vibrio cholera, XcpT also called PddA (Q00514) in Pseudomonas aeruginosa or PulG (P15746)in Klebsiella pneumoniae. The PulG is thought to be anchored in the inner membrane with its C-terminus directed towards the periplasme. Together with other members of the Type II secretion machinery, it is thought to assemble into a pilus-like structure that may function as a dynamic mechanism to push secreted proteins out of the cell. The polypeptide is organized into a long N-terminal alpha-helix followed by a loop region that separates it from a C-terminal anti-parallel beta-sheet.	9.8851e-56
NZ_CP049320.1\|WP_165107447.1\|58160_59303_+\|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380565	cd06342, PBP1_ABC_LIVBP-like, type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.	2.82523e-124
NZ_CP049320.1\|WP_165106842.1\|47797_49201_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	6.54136e-12
NZ_CP049320.1\|WP_165106875.1\|61243_61987_+\|acetoacetyl-CoA-reductase	gnl\|CDD\|273823	TIGR01829, Acetoacetyl-CoA_reductase, acetoacetyl-CoA reductase. This model represent acetoacetyl-CoA reductase, a member of the family short-chain-alcohol dehydrogenases. Note that, despite the precision implied by the enzyme name, the reaction of EC 1.1.1.36 is defined more generally as (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH. Members of this family may act in the biosynthesis of poly-beta-hydroxybutyrate (e.g. Rhizobium meliloti) and related poly-beta-hydroxyalkanoates. Note that the member of this family from Azospirillum brasilense, designated NodG, appears to lack acetoacetyl-CoA reductase activity and to act instead in the production of nodulation factor. This family is downgraded to subfamily for this NodG. Other proteins designated NodG, as from Rhizobium, belong to related but distinct protein families.	4.23365e-121
NZ_CP049320.1\|WP_165106855.1\|56020_56998_+\|agmatinase	gnl\|CDD\|212537	cd11589, Agmatinase_like_1, Agmatinase and related proteins. This family includes known and predicted bacterial agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme, belonging to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. Agmatinase from Deinococcus radiodurans shows approximately 33% of sequence identity to human mitochondrial agmatinase. An analysis of the evolutionary relationship among ureohydrolase superfamily enzymes indicates the pathway involving arginine decarboxylase and agmatinase evolved earlier than the arginase pathway of polyamine.	2.43516e-146
NZ_CP049320.1\|WP_165106824.1\|37487_38015_-\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	6.57041e-28
NZ_CP049320.1\|WP_165106828.1\|40077_41667_-\|galactarate-dehydratase	gnl\|CDD\|274491	TIGR03248, galactar-dH20, galactarate dehydratase. Galactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0714).	0
NZ_CP049320.1\|WP_165106848.1\|51478_52456_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	8.20104e-43
NZ_CP049320.1\|WP_165106852.1\|54003_54504_+\|hypothetical-protein	gnl\|CDD\|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	7.20046e-32
NZ_CP049320.1\|WP_165106826.1\|38142_39135_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270389	cd13671, PBP2_TRAP_SBP_like_3, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.79679e-150
NZ_CP049320.1\|WP_165106839.1\|46569_47343_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.01691e-12
NZ_CP049320.1\|WP_165106822.1\|36132_37485_-\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	1.60754e-110
NZ_CP049320.1\|WP_165106845.1\|50270_51482_+\|AAA-family-ATPase	gnl\|CDD\|274585	TIGR03453, partition_RepA, plasmid partitioning protein RepA. Members of this family are the RepA (or ParA) protein involved in replicon partitioning. All known examples occur in bacterial species with two or more replicons, on a plasmid or the smaller chromosome. Note that an apparent exception may be seen as a pseudomolecule from assembly of an incompletely sequenced genome. Members of this family belong to a larger family that also includes the enzyme cobyrinic acid a,c-diamide synthase, but assignment of that name to members of this family would be in error. [Mobile and extrachromosomal element functions, Plasmid functions].	3.73046e-47
NZ_CP049320.1\|WP_165106861.1\|56998_57934_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.00984e-35

>NZ_CP049320.1|WP_165106842.1|47797_49201_-|replication-initiation-protein
MAADNPEESKSRVTPRQMALALFEDLFDLGMPISEATREIGYQRNNFFTQIVNMGLPARRFLDAAYFIVAQEQEARDQYDVELNYFKWLMRYDSRNLKHLRTIAEEAQDAKIQVTDTPLDRDPNEDDLWVSVQLLGMVGFHRGRIRFDVHPRLVPHIRDPKKSHWLSLRISTAFTRSLARAIYDQILPSVPDGRTEWIPLEEMRNWPGKMGANAAIFKYFKRDWLEPAVREINEVSDIDLTYETRTESTTSKKIDRIRFLLKRKDTADAVLASLADASHLYKILKDEFNLSTKQFTEISENREVWTDTHIQQAVEYTRFKINRGQVKRSPAGYLMRALRDNWKMSEAERTMVDVQSKLLTDETEAEVAKNETRSSVARTMASREEEVRARMNEESLKGREHFNAADLKTRKDLVRSWVTSSQGKLMLRRMKLEASTVTEQDILANADLGWYLGQFVFGRMNSSRTSP
>NZ_CP049320.1|WP_165106839.1|46569_47343_+|alpha/beta-hydrolase
MTQALATFHLSHGPKNRPTLVFLPGALIPPNAIAPVTRIVKLRAIGVGWLEGTGPHDLHSVAARVAMLLRELGPTVLIGHSVGTPIAALAAAIDLRSTKRNVAGLVLSNSGANTKGHGDIESVIERVLQTWGPPLWKAMTERSLGSVCPAELVDSFMTYPRRVTAEATAESLRSLQHTDLTDMLNELSSLPTAVVHGSRDPARNLSHAESLSNGIPGSRLVVLETGHTSCVEAPDEFAEVIRSVVEQGLKPGAASAD
>NZ_CP049320.1|WP_165106836.1|46019_46484_+|type-II-secretion-system-major-pseudopilin-GspG
MQMGTNRRTDIAALRSHDQRGFTFRKIAVVVAMLALLITLIVSKIMSGPEEAKRVAAKQDIGTIVQALKLYRHDSGRYPTQEQGLRALIEKPATSPVPNFWKDGGYLQRLPNDPWGNAYQYLNPGVHGEVDVFSYGADAKQGGEDSDADIGSWE
>NZ_CP049320.1|WP_165107445.1|43000_44356_+|MFS-transporter
MTMEMRRTASPSHVAKRTNVRYAILLLIFLITTLNYADRATLSVTGSAMRAEFGLDAIRLGYIFSAFSWAYVLSQLPAGWLLDRFGARRVYAASIFLWSLFTLLQGAIGLLGSAAAAITALFVLRFAMGAAESPAFPANAKVVANWFPTTERGMASAIFNSAQYFAAVVFTPLMAWLTHAFGWHTVYLVMGMTGLLLAFTWLKVMKNPADHPRVSRAELDYIEQGGGVVNGHKRTQPSDIAGAGGWLLMRQLLTNRMLLGIYLAQYCINVLTYFFLTWFPIYLVQARGMTILHAGLVASLPAICGFSGGVLGGFLSDSLLRRGHSLTLARKAPIVGGMLLSVCIIGCNYVTTDWVVVALMSLAFFGKGIGALGWAVVADTSPKEALGLSGSIFNMFGNVAGIVTPIVIGYLVANTGSFNGALVFVGLNALLTVFSYLVIVKDIKRVELRPR
>NZ_CP049320.1|WP_165106831.1|41869_42787_+|5-dehydro-4-deoxyglucarate-dehydratase
MTTPQELKQIVSKGLLSFPVTDFDEQGEFRADTYAERLEWLAPYGASALFVAGGTGEFFSLTHDDYSKVVRTATEVCRGKVPILAGAGGPTRAAIAYAQEAQRHGANGILLMPHYLTEACQEGIAAHAEEVCKSVPDMGVIIYNRANSKLNADMLEGLAQRCPNLIGFKDGVGEIENMVTIRRRLGDRFAYLGGLPTAEVYAAAYKALGVPVYSSAVFNFIPKTAMDFYHAIAAEDHATVGKLIDEFFLPYLAIRNRRAGYAVSIVKAGAKLVGHSAGPVRAPLTDLTEEEMSKLDALIKALGPQ
>NZ_CP049320.1|WP_165106828.1|40077_41667_-|galactarate-dehydratase
MENSPLYIRVHPNDNVAIVVNDGGLGEGAVFPDGLVLRERVPQGHKVALVDLAEGDEVIRYNVVIGYALKSLPSGSWINEHVIRMPSPPGLEDLPIATIRAPDMPPLEGFTFEGYRNADGSVGSRNILAITTTVQCVADVVQHAVTRIKAELLPHYPNVDDVVGLGHTYGCGVAIDAPDAMVPIRTVRNISLNPNFGGEVMMVSLGCEKLQPERLMPPGTIPIAAAANVAEVADIGDVEADQNGDVVVLQDEAHVGFQSMIDSIMRMADAHLKRLNNRRRETCPAADLVVGVQCGGSDAFSGLTANPAVGFATDLLVRAGATVMFSEVTEVRDGVDQLTARAANADVAAAIIREMQWYDDYLKRGGADRSANTTPGNKKGGLSNIVEKAMGSIIKSGNSAISGVLSPGEKVRQKGLIYAATPASDFICGTLQVAAGINLHVFTTGRGTPYSLAEVPVIKVATRSDLARRWHDLMDINAGTIATGDATIEDVGWELFRLMLEVASGRKETCAEKLKLHNALTLFNPAPVT
>NZ_CP049320.1|WP_165106826.1|38142_39135_-|TRAP-transporter-substrate-binding-protein
MKKKFAYSRVSMIVAATALTFTAVSAQARMFRVSDVHGDTYPTNMAVKYMGEEISKATGGKDTVKVFGNSSLGSENDTLDQVRIGALDMARCNGAAFNEIVPESMIPSLPFLFRDINHFRDVMYGPVGQKILDAFQAKGMIALTFYESGARSIYSKRPIHSPADMKGLKVRVQPSDLMVDEIKAMGGTPTPMPFSEVYTGLKTGLVDAAENNIPSYEETKHFEVAPIYSETQHSMTPEVLVFSKKVWDTLTPQEQVIIKKAAADSVPYYEKLWTARENDASKTVVKGGATIIAANQIDRPAFVKAMQPVWAKYEKTPQMKQLVDEIQAVK
>NZ_CP049320.1|WP_165106824.1|37487_38015_-|TRAP-transporter-small-permease
MKFMKRSNDFLVYVLVSVASVSLAALSLLVFYGVVMRYVFNDAPDFVEPIALLLVIVIAMFGAALKVRENGHIGLDSLVKKLSPKGQVAAEAFQHLCLIAFSAAVFFGCIEMAETTMDDQIPILGLPEALRYLIPIVASACIILFSIEHLLALFTQKQILARAPASVVHAETKTE
>NZ_CP049320.1|WP_165106822.1|36132_37485_-|TRAP-transporter-large-permease
MELAILSVSFIVFLVLGVPVSFALGLACVLTYLHEGLPAATAMQSMISGMNGFSFLAVPFFIFSGELMLHGGIADRILRFAQATVGHFRGGLGMANVVACTLFGGVSGSPSADTSAMGGVVIPLMKREGYSAAYAVNVTTHSSLAGALMPTSTNMIIYAFAAQGITGTLNGHQMSGVSIGDLLFSGLLPVLWVMGFILIAAYWQAVRFGYPRRPDGSTELQRFPGWFAVGRTFLGALPGLMVIAIILVCVAKGIATATEAAAIAVFYSLVLTIVVYRTLTRKKLFLALSKATKTTGVVLLLIGVSNMLRYQMAYLEIPDAIEHLLENATTIPWLMLLYINIIQIFLGTFVDMAAHILITTPLFLPMAMHSGVGPVQFGIMILLNCALGLVHPPIGSVQFIGCAIGNVSIGETTKVAWPYYLAIFSAINIVTYVPMFSTWLPSLINGHPVF
>NZ_CP049320.1|WP_165106819.1|34856_36056_-|porin
MKKVLATSALGLVALGAHAQSSVTLYGIVDTGIGYQSSQTSLGSTSGGRSVVKMVNGIWAGSRFGLKGSEDLGGGTKTIFQLEEGFNSATGAESVAGEAFNRQAYVGLANSTYGTLTAGRQYTSYYTLLSPYSPTTWLTGAYGAHPGDIDSLDTLYRANNSLVYTSPSLHGLTASGSYSMGGVPGSFNAGSTWSAALQYLNGPFGIAAGFQRINNSTPGGGAWGASSTTSNAGAQAGVSGINNGYQTAQAQQRVAVTGGYTFTQQWDVSFSYSNVQYIPGINSQFRHEAIFNTAGAVLHFKPATVLDLAAGYSYTRATEANGISNSAQYQQFNLSQYYSLSKRTGLYALEAYQRASGQTLGTNGVSIINATADIGDGQNSAPSSSRSQFAAGVGIIHRF
>NZ_CP049320.1|WP_165106845.1|50270_51482_+|AAA-family-ATPase
MVKTSQLPAVDRTVHLEQISQFAEKVSIFTDELRDTILAPRPRKAAPVFKTGEIAEMCNIAHSQVQYLATKSDGELPSGTAAGTGRTRTFTLEEARVWVQKVSDIYQTPLVTGTREPEGKIIITAQLKGGSAKTTTTMCLAQGLTLRGRKVLVVDLDPQASLSELCGLYAEKDVTPDDTILPYIYDQDIEGGLEARVQSTYWNGLDVIPAHTELIGAEFHLPAMQKMRPGFRFWTVLRQGLEPLRKRYDYILMDTSPSLSYLNLNALLAADAMVMPMVPENLDFISSLSFWRLFSDVSKSFMKYETDKKYDFISLLLSRVDYGRTSSAPIVRAWAQSAYENWLHSIEVPASSVMSTGALAFSTVFDVSSTHSASKSLQRVRQPLVDYCRWIDEIYAEKWRNAQ
>NZ_CP049320.1|WP_165106848.1|51478_52456_+|ParB/RepB/Spo0J-family-partition-protein
MSNMREQLLAKTAGIRATSSINGDEVKRSTRTQTAPGLAGALAVAQLRVQELESTGAASKLVVSDVVPNPWQPRRVFNEAKLSELAESIREVGLMQPIVVRRSEENYQIVAGERRWRAHKMVGFDTINAVVVECSDADMAVLALVENVSRDDLSDYEVATSIRQTEKEFPDRKRMAEALGMSRSGLYQFLSFENLPDFIRKDLDIQPRLLGGTAAQAIVTAIKKHGNGGLTAALELWPLVVKGDMDQGKVAAAIKALATRQTTTANSASERSIDKFFSGKEHAGSITKDISGITVKIKSGVLTDVQETQIRELISQMFHAQPKAS
>NZ_CP049320.1|WP_165106852.1|54003_54504_+|hypothetical-protein
MATTNRSATRLPAEALVAGHRDLMKALMKDALQEVLEAEMTEQLGATSNERTEVRSGYGAGYYGRGLIPRIGKLELCVPRDRHGEFPTALFERYARSERHWSPPRRNVCAGRVHAQGEGDYGHSFSASAVSAINKGLDATLAKFAHRPLEEGIPVPDVDACRSICG
>NZ_CP049320.1|WP_165106855.1|56020_56998_+|agmatinase
MSENSYETGRLNLPFVGICTFAKSPLCLDWDKIGADVAVMGAPFDCGTQWRAGARFGPRSIRDASTLFSFGHGGAYDFEDDVVYLPSDEVRIVDIGDADMVHTNTEKSHANIEYGVRKILAAGALPVVMGGDHSINIPCINAFEGQEPFHIVHIDAHLDFVDERHGVRYGHGNPLRRAAEKSVVSGMTQIGIRNVSSTAREGYAQAREMGSDIISVRDLRRLGIQGVLDRIPKGVRYYLTIDIDGFDPSIAPGTGTPSHGGLLYYEGLELFAGLAAQGDVIGIDLVEVAPDYDHSGSTSILAAQLLLNTIGRVMHQRKVKRNLSR
>NZ_CP049320.1|WP_165106861.1|56998_57934_-|LysR-family-transcriptional-regulator
MQVQDTDLKLLRIFETIVRCGGFSAAQPILNIGASSISEYMSQLETRLGLRLCERGRAGFRLTEEGAELHAAAQRLLGAVDTFHMEAGALRNQLSGVLRFGMIEATLTDKYSPLPIAIREFGQMAPEVRLHVQIETPGSMEQHVLDGRLHLAVGPFPAQIPGLDYLPLYREEQGLYCASTHPLHERASGRVSVSLLSKQRLAARAYLGSQELKLLRMPEAAASVDNVEGRAMLILSGNYIGFLPPHYAQPWVHSGLLTRIDPEHYATHLDFQIITRKGGESARVVQAFCNQLRAAGKQVGRAPRSGKQRAD
>NZ_CP049320.1|WP_165107447.1|58160_59303_+|branched-chain-amino-acid-ABC-transporter-substrate-binding-protein
MNKPYAGASWVTTVALSMISLSATAGDQVVKIGLTGPLTGAQAAIGKDDENGVRMAIERLNAKGLVIGGQKTRFELVSQDDAADPRTGMTVAQSLVDANVKVIFGPFNSGVAIPISNLVNVSGIVMATVASNPSITQHGYPFVFRISASDTQLGSRMGEFAAKELKVKRIAVIDDRTAYGQGVADEFVNAAKANGIEIVDREYTTDKATDFVSILTHVKGSNAEGIFYGGYYAQAGALRKQMKRLAMNGYLLGGDAMCNAELAKLGGDAVDTRVYCPQGGPVLDQTPEGRRFKADYKQRFHTDPLTYSAALYDGVNIVAQAMTKANSIEPAQYRAALANIDSHGVSGHYQFDKNRDLTDSPITIYNYRNGEPTPLASAQP
>NZ_CP049320.1|WP_165106864.1|59568_59874_+|panthothenate-synthetase
MRMLLNIRIPHEPFNAFVRDGSIGELIEKILAESKPEAAYFTEQNGTRGAILIVDLEEPSQIPKFAEPWFLTFNADCEFRVVMVADDLKRAGLEMLGSKWK
>NZ_CP049320.1|WP_165106875.1|61243_61987_+|acetoacetyl-CoA-reductase
MTKRIAVVTGGMGGLGEAISTKLHDAGYAVVVTHSPNNAGAAEWLANMETQGRGFRAYPVDVADYDSSQHCAARIQVEVGPVDILVNNAGITRDMTLRKMDKVNWDSVIRTNLDSVFNMTKPLCEDMVARGWGRIINISSVNGSKGSVGQTNYAAAKAGIHGFTKSLALEVARKGVTVNTISPGYLATKMVTAIPQEILDTKVLPHIPMGRLGKPEEVAALVAYLCSDDAGFVTGSNIAINGGQHMQ
>NZ_CP049320.1|WP_165106877.1|62293_62560_+|hypothetical-protein
MTPKIAGLLTATGHQITVRTSSGGMRVAAIWQVLMPVARDIECVRIVTNSERGFEDMTISFSETIPGSLNAVLRQFEKMTWVATAQLC
>NZ_CP049320.1|WP_165106879.1|62748_63003_+|hypothetical-protein
MKTTIKKGPGDMGSPYTPQNAEDAISHLERILSADGADSLFNRTYWRARVQQVSATRGLTPQQRARLARLLESLPSPVRGEEPS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049320_1	1.1\|49729\|43\|NZ_CP049320\|PILER-CR	49729-49771	43	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	497576-497618	0	1.0
NZ_CP049320_1	1.1\|49729\|43\|NZ_CP049320\|PILER-CR	49729-49771	43	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	49729-49771	0	1.0
NZ_CP049320_1	1.3\|49888\|59\|NZ_CP049320\|PILER-CR	49888-49946	59	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	497735-497793	0	1.0
NZ_CP049320_1	1.3\|49888\|59\|NZ_CP049320\|PILER-CR	49888-49946	59	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	49888-49946	0	1.0
NZ_CP049320_1	1.2\|49793\|74\|NZ_CP049320\|PILER-CR	49793-49866	74	NZ_CP049159	Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence	497640-497713	14	0.811
NZ_CP049320_1	1.2\|49793\|74\|NZ_CP049320\|PILER-CR	49793-49866	74	NZ_CP049320	Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence	49793-49866	14	0.811

1. spacer 1.1|49729|43|NZ_CP049320|PILER-CR matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 0, identity: 1.0

gtgatgggaaaagagaccggtacggaggatggcgagcaaaatt	CRISPR spacer
gtgatgggaaaagagaccggtacggaggatggcgagcaaaatt	Protospacer
*******************************************

2. spacer 1.1|49729|43|NZ_CP049320|PILER-CR matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 0, identity: 1.0

gtgatgggaaaagagaccggtacggaggatggcgagcaaaatt	CRISPR spacer
gtgatgggaaaagagaccggtacggaggatggcgagcaaaatt	Protospacer
*******************************************

3. spacer 1.3|49888|59|NZ_CP049320|PILER-CR matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 0, identity: 1.0

gatttacgctttggcctttttgcggagatttttcgcgcttgttccggaaatccgggtac	CRISPR spacer
gatttacgctttggcctttttgcggagatttttcgcgcttgttccggaaatccgggtac	Protospacer
***********************************************************

4. spacer 1.3|49888|59|NZ_CP049320|PILER-CR matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 0, identity: 1.0

gatttacgctttggcctttttgcggagatttttcgcgcttgttccggaaatccgggtac	CRISPR spacer
gatttacgctttggcctttttgcggagatttttcgcgcttgttccggaaatccgggtac	Protospacer
***********************************************************

5. spacer 1.2|49793|74|NZ_CP049320|PILER-CR matches to NZ_CP049159 (Caballeronia sp. SBC1 plasmid pSBC1_3, complete sequence) position: , mismatch: 14, identity: 0.811

ttgcatcaccgctggtccgtgctcgcgggtttttccactaaaaatatattagggaacgtc	CRISPR spacer
ttgcatcaccgctggtccgtgctcgcgggtttttccactaaaaatatattagggaacgtc	Protospacer
************************************************************

6. spacer 1.2|49793|74|NZ_CP049320|PILER-CR matches to NZ_CP049320 (Caballeronia sp. SBC2 plasmid pSBC2-4, complete sequence) position: , mismatch: 14, identity: 0.811

ttgcatcaccgctggtccgtgctcgcgggtttttccactaaaaatatattagggaacgtc	CRISPR spacer
ttgcatcaccgctggtccgtgctcgcgggtttttccactaaaaatatattagggaacgtc	Protospacer
************************************************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

149402 : 187006

uncultured_Caudovirales_phage(40.0%)

transposase,integrase,bacteriocin

attL 139514:139530|attR 199260:199276

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
139514:139530	attL	NA	NA	NA	NA
WP_165107053.1\|149402_149972_+\|bacteriocin	bacteriocin-protection protein	NA	NA	NA	NA
WP_165107055.1\|152178_152514_-	HdeA	NA	NA	NA	NA
WP_165107057.1\|153267_154188_-	VOC family protein	NA	NA	NA	NA
WP_165107059.1\|154184_155099_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_165107062.1\|155109_155595_-	cupin domain-containing protein	NA	NA	NA	NA
WP_165107065.1\|155630_156119_-	DoxX family protein	NA	NA	NA	NA
WP_165107068.1\|156141_157719_-	GMC family oxidoreductase	NA	NA	NA	NA
WP_165107070.1\|157990_158986_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_165107073.1\|159212_161000_+	glycoside hydrolase family 15 protein	NA	NA	NA	NA
WP_165107076.1\|161078_161954_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	5.7e-18	32.7
WP_165107472.1\|161991_162303_-	cytochrome-c oxidase	NA	NA	NA	NA
WP_165107078.1\|162341_162965_-	cytochrome o ubiquinol oxidase subunit III	NA	NA	NA	NA
WP_165107475.1\|162961_165004_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_165107080.1\|165069_166164_-	cytochrome ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_165107083.1\|167399_168110_-	YfdX family protein	NA	NA	NA	NA
WP_165107085.1\|168895_171136_+	DUF3141 domain-containing protein	NA	NA	NA	NA
WP_165107087.1\|171314_172079_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_165107091.1\|172220_173582_+	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase	NA	NA	NA	NA
WP_165107094.1\|173588_174767_+	acetate/propionate family kinase	NA	NA	NA	NA
WP_165107098.1\|174923_177512_+	plasma-membrane proton-efflux P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	7.6e-50	25.6
WP_165107101.1\|177555_178425_+	polyphosphate kinase 2 family protein	NA	NA	NA	NA
WP_165107104.1\|178522_178678_-	hypothetical protein	NA	NA	NA	NA
WP_165107108.1\|178999_179878_+\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	5.9e-31	29.9
WP_165106719.1\|180011_181460_+\|integrase	site-specific integrase	A0A2H4J165	uncultured_Caudovirales_phage	1.1e-34	29.3
WP_165106446.1\|181456_183337_+\|integrase	integrase	A0A2H4J9J6	uncultured_Caudovirales_phage	8.6e-19	24.9
WP_165106449.1\|183333_185220_+\|integrase	integrase	NA	NA	NA	NA
WP_165106452.1\|185216_185579_+	hypothetical protein	NA	NA	NA	NA
WP_165107478.1\|185785_187006_+\|transposase	IS91 family transposase	NA	NA	NA	NA
199260:199276	attR	NA	NA	NA	NA

DBSCAN-SWA_2

251723 : 281920

Escherichia_phage(25.0%)

transposase,integrase

attL 248698:248712|attR 261661:261675

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
248698:248712	attL	NA	NA	NA	NA
WP_165107223.1\|251723_252941_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165107225.1\|253572_255459_-	UvrD-helicase domain-containing protein	NA	NA	NA	NA
WP_165107227.1\|255445_255850_-	hypothetical protein	NA	NA	NA	NA
WP_165107230.1\|256051_256633_-	DUF4393 domain-containing protein	NA	NA	NA	NA
WP_165097078.1\|256886_257387_+	hypothetical protein	NA	NA	NA	NA
WP_147408238.1\|257358_257757_+	hypothetical protein	NA	NA	NA	NA
WP_165097075.1\|257749_259237_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	5.9e-31	31.5
WP_165097072.1\|259214_260015_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.6e-38	37.6
WP_165107232.1\|260361_260808_-	DNA-binding protein	NA	NA	NA	NA
WP_165107236.1\|261301_262129_+	H-NS histone family protein	NA	NA	NA	NA
261661:261675	attR	NA	NA	NA	NA
WP_165107239.1\|262877_263387_+	hypothetical protein	NA	NA	NA	NA
WP_165107243.1\|263444_263648_+	hypothetical protein	NA	NA	NA	NA
WP_165107246.1\|264999_265362_-	hypothetical protein	NA	NA	NA	NA
WP_165107249.1\|265542_265788_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165107252.1\|266654_268022_-	hypothetical protein	NA	NA	NA	NA
WP_165105095.1\|268346_268526_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165105092.1\|268601_268943_-	hypothetical protein	NA	NA	NA	NA
WP_165086648.1\|269699_270923_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	6.5e-52	32.7
WP_165086650.1\|270946_272177_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.1e-139	86.6
WP_165105089.1\|272928_273927_-	ATP-binding protein	NA	NA	NA	NA
WP_165107256.1\|273929_276743_-	hypothetical protein	NA	NA	NA	NA
WP_165090795.1\|278870_280295_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_165107259.1\|280435_281920_+\|transposase	ISNCY family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_CP049318

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

47245 : 87793

Tupanvirus(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165101896.1\|47245_48148_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_165101899.1\|48211_49216_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_165101903.1\|49293_50250_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165101906.1\|50324_51431_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_165101909.1\|52108_52390_-	hypothetical protein	NA	NA	NA	NA
WP_165101912.1\|52692_54087_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_097268962.1\|54139_55384_+	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_165101915.1\|55405_55708_+	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_165101918.1\|55704_58707_+	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_165101921.1\|58696_59347_+	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_165101924.1\|59343_59805_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_165101927.1\|59812_60076_+	hypothetical protein	NA	NA	NA	NA
WP_165101932.1\|60170_61859_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.0e-52	29.3
WP_165101935.1\|61870_63340_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_165101938.1\|63351_63960_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_165101941.1\|64171_65371_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.1e-11	27.7
WP_165101944.1\|65413_66430_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_165101947.1\|66871_68161_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	3.7e-106	54.2
WP_165101950.1\|68188_69160_+	membrane dipeptidase	NA	NA	NA	NA
WP_165101953.1\|69192_69729_+	4-vinyl reductase	NA	NA	NA	NA
WP_165101956.1\|69778_71842_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_165101959.1\|71844_73764_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_165101962.1\|73767_74958_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_165101965.1\|74854_75793_+	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_165101968.1\|75867_77166_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_165101971.1\|77208_78420_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_165101974.1\|78562_79426_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165101977.1\|79521_80418_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_165101980.1\|80555_81476_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_165101983.1\|81619_83158_+\|holin	choline-sulfatase	A0A2K9L727	Tupanvirus	1.0e-22	26.8
WP_165104842.1\|83243_84161_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165101986.1\|84424_85573_+	porin	NA	NA	NA	NA
WP_165101991.1\|85589_86573_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_165101994.1\|86836_87793_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_2

107978 : 159284

Leptospira_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165086648.1\|107978_109202_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	6.5e-52	32.7
WP_165086650.1\|109225_110456_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.1e-139	86.6
WP_165102028.1\|110627_111728_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_165102030.1\|112080_112764_+	hypothetical protein	NA	NA	NA	NA
WP_165102031.1\|112917_113958_-	FUSC family protein	NA	NA	NA	NA
WP_165102033.1\|114278_115727_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_165102035.1\|115773_116190_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_165102037.1\|116176_116413_-	DNA-binding protein	NA	NA	NA	NA
WP_165102039.1\|116601_119319_-	aconitate hydratase AcnA	NA	NA	NA	NA
WP_165102041.1\|119391_120843_-	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA	NA	NA	NA
WP_165102044.1\|120868_121405_-	hypothetical protein	NA	NA	NA	NA
WP_165102047.1\|121546_122719_-	2-methylcitrate synthase	NA	NA	NA	NA
WP_165102051.1\|122749_123745_-	CoA ester lyase	NA	NA	NA	NA
WP_165102054.1\|123912_124899_-	malate dehydrogenase	NA	NA	NA	NA
WP_165102057.1\|125498_126287_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_165102060.1\|126455_126866_+	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_165102064.1\|126868_127243_+	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_165102067.1\|127246_129025_+	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_031362534.1\|129040_129745_+	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_062086335.1\|129759_130032_+	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_165102070.1\|130108_131410_+	citrate (Si)-synthase	NA	NA	NA	NA
WP_165102073.1\|131678_131894_+	DUF3079 domain-containing protein	NA	NA	NA	NA
WP_165102076.1\|131908_132316_-	type II secretion system protein	NA	NA	NA	NA
WP_165102079.1\|132372_132756_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_165102082.1\|132763_133246_-	type II secretion system protein	NA	NA	NA	NA
WP_165102085.1\|133247_135608_-	hypothetical protein	J7HXF0	Enterobacteria_phage	4.2e-15	23.9
WP_165102088.1\|135619_136234_-	hypothetical protein	NA	NA	NA	NA
WP_165102091.1\|136230_136812_-	hypothetical protein	NA	NA	NA	NA
WP_165102094.1\|136808_137183_-	PilN domain-containing protein	NA	NA	NA	NA
WP_165102099.1\|137345_138923_-\|transposase	IS66 family transposase	S5VLC8	Leptospira_phage	3.5e-42	34.6
WP_062093253.1\|139009_139363_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_165102103.1\|139362_139827_-\|transposase	transposase	NA	NA	NA	NA
WP_165102107.1\|140027_140774_-	hypothetical protein	NA	NA	NA	NA
WP_165104847.1\|140838_142422_-	type II/IV secretion system protein	NA	NA	NA	NA
WP_165102111.1\|142559_143816_-	type II secretion system F family protein	NA	NA	NA	NA
WP_165102115.1\|143861_144287_-	type II secretion system major pseudopilin GspG	NA	NA	NA	NA
WP_165102119.1\|144892_145114_+	RHS repeat protein	NA	NA	NA	NA
WP_165102122.1\|145452_151218_+	RHS repeat protein	S5VY91	Leptospira_phage	1.2e-07	22.7
WP_165102028.1\|151329_152430_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_165102125.1\|152479_152830_+	hypothetical protein	NA	NA	NA	NA
WP_165102130.1\|153270_153492_-	type I toxin-antitoxin system SymE family toxin	NA	NA	NA	NA
WP_165102134.1\|153596_153989_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165102138.1\|154092_156984_+	toprim domain-containing protein	A0A1S5RG58	Helicobacter_phage	5.3e-20	25.3
WP_165097072.1\|157018_157819_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.6e-38	37.6
WP_165097075.1\|157796_159284_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	5.9e-31	31.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_CP049319

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

186948 : 280505

uncultured_Caudovirales_phage(28.57%)

integrase,transposase

attL 241877:241892|attR 277942:277957

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165087520.1\|186948_188352_-\|transposase	transposase	NA	NA	NA	NA
WP_075358900.1\|188884_190261_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	2.5e-84	37.0
WP_165105446.1\|190485_192216_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.3e-10	58.5
WP_165105449.1\|192251_192809_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_165105461.1\|193001_194483_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	6.2e-73	35.3
WP_165105464.1\|194657_195605_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165105467.1\|195704_196742_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_165106542.1\|196788_198303_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.2e-16	31.1
WP_165105470.1\|198337_199588_-	ROK family transcriptional regulator	NA	NA	NA	NA
WP_165105473.1\|200668_201436_+	hypothetical protein	NA	NA	NA	NA
WP_165105476.1\|201651_201876_-	CDGSH iron-sulfur domain-containing protein	NA	NA	NA	NA
WP_165105487.1\|202219_203308_+	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_165105490.1\|203300_204281_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_165105493.1\|204285_205401_+	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_165105496.1\|207150_208521_+	MHS family MFS transporter	Q6JIH2	Burkholderia_virus	3.6e-43	33.1
WP_165105499.1\|209471_209699_+	hypothetical protein	NA	NA	NA	NA
WP_165105501.1\|210068_210329_-	transcriptional regulator	NA	NA	NA	NA
WP_165105504.1\|210506_210803_-	hypothetical protein	NA	NA	NA	NA
WP_165105507.1\|212357_212753_+	hypothetical protein	NA	NA	NA	NA
WP_165105510.1\|213168_213390_-	dodecin domain-containing protein	NA	NA	NA	NA
WP_165105513.1\|213702_215022_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105513.1\|215336_216656_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105515.1\|218825_218972_+	hypothetical protein	NA	NA	NA	NA
WP_165105518.1\|219813_221118_-	hypothetical protein	NA	NA	NA	NA
WP_165105521.1\|222473_222938_+\|transposase	transposase	NA	NA	NA	NA
WP_165105523.1\|222937_223291_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	3.3e-09	40.5
WP_165105526.1\|224842_225838_-\|integrase	tyrosine-type recombinase/integrase	A0A076YL28	Mesorhizobium_phage	4.0e-07	28.6
WP_165105529.1\|225834_226782_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105532.1\|226778_228011_-\|integrase	tyrosine-type recombinase/integrase	A0A1L4BKH1	Thermus_phage	1.4e-06	30.3
WP_165105534.1\|228463_228601_-	hypothetical protein	NA	NA	NA	NA
WP_165105537.1\|229029_229407_+	EAL domain-containing protein	NA	NA	NA	NA
WP_165105539.1\|230632_233701_+	glycosyl transferase family 51	NA	NA	NA	NA
WP_165105543.1\|234570_234840_-	DUF1488 domain-containing protein	NA	NA	NA	NA
WP_165105546.1\|235171_235369_+	hypothetical protein	NA	NA	NA	NA
WP_165105549.1\|235434_235674_+	hypothetical protein	NA	NA	NA	NA
WP_165106545.1\|236021_237254_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_165105552.1\|237264_237615_+	cytochrome c	NA	NA	NA	NA
WP_165105556.1\|237690_237999_+	twin-arginine translocation pathway signal protein	NA	NA	NA	NA
WP_165105559.1\|238030_238684_+\|transposase	transposase	NA	NA	NA	NA
WP_165106548.1\|239306_240443_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165104999.1\|240389_240671_+	hypothetical protein	NA	NA	NA	NA
WP_165105563.1\|240571_242158_+\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_165106551.1\|241773_242493_+	chromate transporter	NA	NA	NA	NA
241877:241892	attL	NA	NA	NA	NA
WP_165105567.1\|242681_243299_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_165105570.1\|243325_243622_+	hypothetical protein	NA	NA	NA	NA
WP_165105573.1\|243946_245380_-	c-type cytochrome	NA	NA	NA	NA
WP_165105575.1\|245494_247180_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_165105577.1\|247647_248418_+	response regulator	NA	NA	NA	NA
WP_165105581.1\|248659_249112_-	GNAT family N-acetyltransferase	A0A2H4J155	uncultured_Caudovirales_phage	2.6e-14	40.0
WP_165106554.1\|249108_250368_-	MFS transporter	NA	NA	NA	NA
WP_165105593.1\|251228_251999_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.6e-83	66.8
WP_165106557.1\|252013_252331_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165106559.1\|252392_252734_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165105596.1\|252807_253539_-	phosphate regulon transcriptional regulatory protein PhoB	W8CYM9	Bacillus_phage	3.2e-30	36.2
WP_165105598.1\|253556_254261_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_165105601.1\|254269_255064_-	phosphate ABC transporter ATP-binding protein PstB	W8CYL7	Bacillus_phage	1.1e-12	28.4
WP_165105604.1\|255056_255845_-	phosphate ABC transporter ATP-binding protein PstB	G3M9Y6	Bacillus_virus	2.7e-14	29.0
WP_165106561.1\|255831_256689_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_165105606.1\|256688_257720_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_165106564.1\|257780_258794_-	phosphate ABC transporter substrate-binding protein PstS	A0A1D7SRJ6	Cyanophage	3.2e-52	42.0
WP_165105609.1\|259049_259565_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	8.0e-28	41.0
WP_165105612.1\|259567_260638_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_165105614.1\|261663_261864_+	DUF3562 domain-containing protein	NA	NA	NA	NA
WP_165105617.1\|262614_263634_-	phosphate ABC transporter substrate-binding protein PstS	A0A222YW41	Synechococcus_phage	6.6e-50	39.0
WP_165105620.1\|263909_264218_-	acylphosphatase	NA	NA	NA	NA
WP_165106567.1\|264251_265589_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_165105623.1\|265603_267061_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_165105626.1\|267070_267949_-	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_165105628.1\|268125_268650_+	arsenate reductase (azurin) small subunit	NA	NA	NA	NA
WP_165105631.1\|268666_271144_+	arsenate reductase (azurin) large subunit	NA	NA	NA	NA
WP_165106569.1\|271364_272882_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.9e-14	25.2
WP_165105635.1\|272871_273648_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.1e-31	36.5
WP_165106571.1\|273736_274831_+	GTP 3',8-cyclase MoaA	NA	NA	NA	NA
WP_165105638.1\|274910_275333_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	5.7e-48	67.2
WP_165105642.1\|275329_276424_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4J2Q2	uncultured_Caudovirales_phage	2.4e-90	58.7
WP_165105654.1\|276800_277895_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105657.1\|278053_278425_+	hypothetical protein	NA	NA	NA	NA
277942:277957	attR	NA	NA	NA	NA
WP_165105660.1\|278405_279179_+	hypothetical protein	NA	NA	NA	NA
WP_165105663.1\|279185_280505_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	4.0e-71	37.8

DBSCAN-SWA_2

296988 : 439488

115

Wolbachia_phage(15.79%)

integrase,transposase

attL 346112:346171|attR 375905:378271

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165105692.1\|296988_298128_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165105694.1\|298572_300105_+	CYTH and CHAD domain-containing protein	NA	NA	NA	NA
WP_165106573.1\|300223_300484_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_165105696.1\|301076_301343_-	hypothetical protein	NA	NA	NA	NA
WP_165106574.1\|301581_302454_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_165105699.1\|302469_303423_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_165105701.1\|303938_304271_+	hypothetical protein	NA	NA	NA	NA
WP_165105704.1\|304524_304893_+	hypothetical protein	NA	NA	NA	NA
WP_165105707.1\|304924_305719_+	hypothetical protein	NA	NA	NA	NA
WP_165105710.1\|305876_306824_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105712.1\|307025_307280_-	hypothetical protein	NA	NA	NA	NA
WP_165105714.1\|307775_308189_-	hypothetical protein	NA	NA	NA	NA
WP_165105717.1\|308608_309556_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_165105720.1\|309716_310844_-	alcohol dehydrogenase catalytic domain-containing protein	E3SJ82	Synechococcus_phage	4.0e-32	29.5
WP_165105722.1\|310840_312505_-	acetolactate synthase large subunit	E4WLQ6	Ostreococcus_tauri_virus	2.0e-27	25.9
WP_165105725.1\|312872_314804_-	acyl CoA:acetate/3-ketoacid CoA transferase	NA	NA	NA	NA
WP_165106575.1\|315219_315993_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_165106577.1\|316103_316517_-	hypothetical protein	NA	NA	NA	NA
WP_165105728.1\|317473_318082_+	chemotaxis protein CheB	NA	NA	NA	NA
WP_165105731.1\|318537_319278_+	DUF748 domain-containing protein	NA	NA	NA	NA
WP_165096086.1\|319377_320604_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_165106579.1\|320654_321059_+	hypothetical protein	NA	NA	NA	NA
WP_165105734.1\|321766_322993_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_165105746.1\|323076_324324_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.9e-27	31.1
WP_165105749.1\|324846_325434_+	hypothetical protein	NA	NA	NA	NA
WP_165105752.1\|325585_326872_+	divalent metal cation transporter	NA	NA	NA	NA
WP_165105754.1\|327134_327443_-	hypothetical protein	NA	NA	NA	NA
WP_165105756.1\|328407_328953_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_165105758.1\|329274_330360_+\|transposase	IS630-like element ISBmu8 family transposase	NA	NA	NA	NA
WP_165106583.1\|330390_330678_+	hypothetical protein	NA	NA	NA	NA
WP_165105002.1\|330841_331006_-	hypothetical protein	NA	NA	NA	NA
WP_165105761.1\|331322_332927_+	AI-2E family transporter	NA	NA	NA	NA
WP_165092324.1\|332941_334267_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.5e-98	43.2
WP_165105764.1\|334628_334958_+	hypothetical protein	NA	NA	NA	NA
WP_165105766.1\|335283_335985_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_165105769.1\|336810_337275_-	hypothetical protein	NA	NA	NA	NA
WP_165105772.1\|339325_339721_-	hypothetical protein	NA	NA	NA	NA
WP_165105774.1\|340036_341029_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_165105778.1\|342469_344206_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
346112:346171	attL	NA	NA	NA	NA
WP_165098388.1\|346123_348208_-	recombinase family protein	NA	NA	NA	NA
WP_165101472.1\|348197_348461_-	hypothetical protein	NA	NA	NA	NA
WP_165098391.1\|348478_348931_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_165101478.1\|349119_349374_-\|transposase	transposase	NA	NA	NA	NA
WP_165098394.1\|350224_351013_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.0e-37	36.6
WP_165106595.1\|352342_352693_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105782.1\|353186_353366_+	hypothetical protein	NA	NA	NA	NA
WP_165105786.1\|353411_354740_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.8e-95	43.3
WP_165092324.1\|355033_356359_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	8.5e-98	43.2
WP_165105790.1\|357343_357517_+	DUF3309 family protein	NA	NA	NA	NA
WP_165106599.1\|357750_358377_+	chemotaxis protein CheB	NA	NA	NA	NA
WP_165105793.1\|358410_359280_-	polyphosphate kinase 2 family protein	NA	NA	NA	NA
WP_165105796.1\|360719_360884_+	hypothetical protein	NA	NA	NA	NA
WP_165105800.1\|361070_361301_+	hypothetical protein	NA	NA	NA	NA
WP_165105803.1\|361405_361585_+	CsbD family protein	NA	NA	NA	NA
WP_165105813.1\|362114_362972_-\|integrase	tyrosine-type recombinase/integrase	A0A1U9WS15	Gordonia_phage	7.6e-07	24.0
WP_165105816.1\|363578_364007_+	response regulator	NA	NA	NA	NA
WP_165105819.1\|365571_367080_-\|transposase	transposase family protein	NA	NA	NA	NA
WP_165105821.1\|367137_367989_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.6e-26	33.1
WP_165105824.1\|367985_369485_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_165105826.1\|369936_373719_-	response regulator	W8CYM9	Bacillus_phage	2.1e-08	34.2
WP_165105827.1\|374185_374344_+	hypothetical protein	NA	NA	NA	NA
WP_165105828.1\|374340_374847_-	recombinase family protein	A0A1S5Y2X8	uncultured_archaeal_virus	5.7e-18	36.2
WP_165098388.1\|375916_378001_-	recombinase family protein	NA	NA	NA	NA
WP_165101472.1\|377990_378254_-	hypothetical protein	NA	NA	NA	NA
WP_165098391.1\|378271_378724_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
375905:378271	attR	NA	NA	NA	NA
WP_165101478.1\|378912_379167_-\|transposase	transposase	NA	NA	NA	NA
WP_062644743.1\|380027_380783_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.0e-80	60.8
WP_165105829.1\|383259_383406_-	hypothetical protein	NA	NA	NA	NA
WP_006413561.1\|383560_383707_-	DUF3096 domain-containing protein	NA	NA	NA	NA
WP_165105830.1\|383768_384356_-	twin-arginine translocation pathway signal	NA	NA	NA	NA
WP_165105831.1\|384755_385385_-	BON domain-containing protein	NA	NA	NA	NA
WP_165105832.1\|386257_386647_+	PRC-barrel domain containing protein	NA	NA	NA	NA
WP_165105833.1\|386713_386902_+	CsbD family protein	NA	NA	NA	NA
WP_165105834.1\|387135_388200_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_165105835.1\|389488_389842_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.0e-18	38.7
WP_165105836.1\|389817_390345_-\|transposase	transposase	NA	NA	NA	NA
WP_165105838.1\|390364_391354_+	ATPase	NA	NA	NA	NA
WP_165105840.1\|391784_391988_+	cold shock domain-containing protein	NA	NA	NA	NA
WP_165105843.1\|393373_393817_-	ester cyclase	NA	NA	NA	NA
WP_165106602.1\|394758_394953_-	hypothetical protein	NA	NA	NA	NA
WP_165105845.1\|395769_396390_-	cytochrome c4	NA	NA	NA	NA
WP_165106606.1\|396444_397773_-	cytochrome C	NA	NA	NA	NA
WP_165106609.1\|398475_398787_-	High potential iron-sulfur protein	NA	NA	NA	NA
WP_165105850.1\|399002_399491_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_165105853.1\|399889_400711_+	ATPase	NA	NA	NA	NA
WP_165105857.1\|401099_401765_+	hypothetical protein	NA	NA	NA	NA
WP_165102141.1\|402700_402880_+	hypothetical protein	NA	NA	NA	NA
WP_165104848.1\|402896_404516_+\|transposase	transposase	NA	NA	NA	NA
WP_165105861.1\|405998_407051_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165105865.1\|407411_408329_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_165105869.1\|408479_408890_+	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_165105873.1\|408892_409267_+	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_165105877.1\|409270_411049_+	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_165105881.1\|411064_411769_+	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_165105884.1\|411883_412909_+	ferrochelatase	NA	NA	NA	NA
WP_165105886.1\|413294_414908_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_165105888.1\|414986_415418_-	DUF3429 domain-containing protein	NA	NA	NA	NA
WP_165105890.1\|415414_416164_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_165106612.1\|416213_416963_-	GTP cyclohydrolase I	A0A1C3NFQ1	Phage_NCTB	3.0e-60	49.6
WP_165105893.1\|416973_417942_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_165105895.1\|418490_418991_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_165105898.1\|420046_420805_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.9e-65	52.1
WP_165105900.1\|422141_423659_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.6e-124	46.8
WP_165105902.1\|424716_425103_+	photoactive yellow protein	NA	NA	NA	NA
WP_165105905.1\|425109_426351_+	AMP-binding protein	NA	NA	NA	NA
WP_165105907.1\|426578_427373_-	EAL domain-containing protein	NA	NA	NA	NA
WP_165105909.1\|427501_428779_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	2.7e-16	39.7
WP_165106614.1\|428787_429120_-	phosphonate transporter	NA	NA	NA	NA
WP_165105005.1\|429611_429776_+	hypothetical protein	NA	NA	NA	NA
WP_165105912.1\|430374_430794_+	hypothetical protein	NA	NA	NA	NA
WP_165106616.1\|431150_432167_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105914.1\|433583_434381_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	6.6e-29	32.9
WP_165105916.1\|435652_436807_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105919.1\|436963_437806_-	NAD(P)-dependent oxidoreductase	A0A1V0SKV4	Klosneuvirus	1.1e-05	36.1
WP_165105916.1\|438333_439488_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

448263 : 521866

Pseudomonas_phage(40.0%)

integrase,transposase

attL 437826:437885|attR 520204:521949

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
437826:437885	attL	NA	NA	NA	NA
WP_165105934.1\|448263_451341_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	6.2e-51	25.1
WP_165105936.1\|451415_452360_-\|integrase	integrase	NA	NA	NA	NA
WP_165105939.1\|452538_453717_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165106627.1\|453859_457258_+	DEAD/DEAH box helicase family protein	A0A0N7D8L3	Dasychira_pudibunda_nucleopolyhedrovirus	4.5e-50	31.4
WP_165105943.1\|458118_458373_+	hypothetical protein	NA	NA	NA	NA
WP_165105946.1\|458475_459789_-	c-type cytochrome	NA	NA	NA	NA
WP_165105949.1\|459800_461579_-	GMC family oxidoreductase	NA	NA	NA	NA
WP_165105953.1\|461778_462474_-	VIT family protein	NA	NA	NA	NA
WP_165105957.1\|463021_463753_-	gluconate 2-dehydrogenase subunit 3 family protein	NA	NA	NA	NA
WP_165105960.1\|463884_464313_-	response regulator	NA	NA	NA	NA
WP_165106629.1\|464618_465752_+	HAMP domain-containing histidine kinase	A0A1B0VMK3	Pseudomonas_phage	1.3e-09	23.1
WP_165105963.1\|465874_467002_-	DUF748 domain-containing protein	NA	NA	NA	NA
WP_165105007.1\|467074_467434_+	hypothetical protein	NA	NA	NA	NA
WP_165105692.1\|467593_468733_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165105966.1\|468685_469885_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105970.1\|470414_471719_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.1e-28	28.7
WP_165105973.1\|472270_473524_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	7.4e-27	28.9
WP_165105975.1\|475647_476673_+	ATPase	NA	NA	NA	NA
WP_165105978.1\|477214_479179_+	AAA family ATPase	NA	NA	NA	NA
WP_165105980.1\|479254_479386_-	TraB/GumN family protein	NA	NA	NA	NA
WP_165105983.1\|479598_480645_-	hypothetical protein	NA	NA	NA	NA
WP_165105985.1\|480741_481698_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_165105988.1\|482156_482441_+	hypothetical protein	NA	NA	NA	NA
WP_165089544.1\|482504_483854_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	7.9e-59	32.3
WP_165105990.1\|483792_484563_+	hypothetical protein	NA	NA	NA	NA
WP_165105993.1\|484940_485567_+	hypothetical protein	NA	NA	NA	NA
WP_165105995.1\|486223_487441_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165105011.1\|487453_487690_-	hypothetical protein	NA	NA	NA	NA
WP_165105998.1\|488422_489841_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_165106000.1\|490202_491063_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_165106003.1\|491332_491803_-	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_165106006.1\|491799_492327_-	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_165106009.1\|492725_493847_-	OmpA family protein	NA	NA	NA	NA
WP_165106011.1\|493984_496000_-	DUF3494 domain-containing protein	NA	NA	NA	NA
WP_165106014.1\|496940_497228_+	hypothetical protein	NA	NA	NA	NA
WP_165106016.1\|497277_500355_+	EAL domain-containing protein	G3MA91	Bacillus_virus	3.3e-20	32.7
WP_165106019.1\|500967_501519_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165106021.1\|501535_501976_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_165106024.1\|502087_503002_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_165106632.1\|503496_504252_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_165106026.1\|504975_505644_+\|transposase	transposase	A0A146ICT8	Staphylococcus_phage	3.3e-05	35.3
WP_165106030.1\|507650_508079_-	response regulator	NA	NA	NA	NA
WP_165106034.1\|508173_508461_+	hypothetical protein	NA	NA	NA	NA
WP_165106037.1\|508818_509868_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_165106040.1\|511351_512356_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	5.8e-22	27.9
WP_165106042.1\|512373_512661_+	hypothetical protein	NA	NA	NA	NA
WP_165106045.1\|512713_513046_+	hypothetical protein	NA	NA	NA	NA
WP_165106049.1\|517762_518557_+	EAL domain-containing protein	NA	NA	NA	NA
WP_165106051.1\|518784_519177_-	hypothetical protein	Q75ZG1	Hepacivirus	3.3e-05	25.7
WP_165105916.1\|520711_521866_-\|transposase	IS110 family transposase	NA	NA	NA	NA
520204:521949	attR	NA	NA	NA	NA

DBSCAN-SWA_4

526823 : 672273

100

Stx2-converting_phage(26.09%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165089859.1\|526823_527906_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165089862.1\|527919_528219_+	hypothetical protein	NA	NA	NA	NA
WP_165106067.1\|529025_529136_+	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_165106070.1\|529622_530966_+	sorbosone dehydrogenase family protein	NA	NA	NA	NA
WP_165106072.1\|531021_532053_-	DUF748 domain-containing protein	NA	NA	NA	NA
WP_165106075.1\|532421_533066_-	hemolysin III family protein	NA	NA	NA	NA
WP_165106077.1\|534180_535308_+	DUF748 domain-containing protein	NA	NA	NA	NA
WP_165106634.1\|535430_535964_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_165106000.1\|536171_537032_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_165106079.1\|539109_540042_-	formate dehydrogenase subunit beta	NA	NA	NA	NA
WP_165106637.1\|540051_543120_-	formate dehydrogenase-N subunit alpha	NA	NA	NA	NA
WP_165106639.1\|543424_543679_+	beta-xylosidase	NA	NA	NA	NA
WP_165106082.1\|543693_543870_-	hypothetical protein	NA	NA	NA	NA
WP_165106084.1\|548920_550057_-	alcohol dehydrogenase catalytic domain-containing protein	E3SJ82	Synechococcus_phage	5.9e-07	25.7
WP_165106086.1\|550886_551048_-	hypothetical protein	NA	NA	NA	NA
WP_165106642.1\|555870_556368_+	hypothetical protein	NA	NA	NA	NA
WP_165106087.1\|556513_556849_-	hypothetical protein	NA	NA	NA	NA
WP_165106088.1\|557016_557292_-	DUF190 domain-containing protein	NA	NA	NA	NA
WP_165106089.1\|558077_559080_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165106090.1\|559832_560831_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	2.3e-23	25.9
WP_165106644.1\|562742_563402_-	ANTAR domain-containing protein	NA	NA	NA	NA
WP_165106091.1\|563386_564541_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_165106094.1\|564982_566530_-	amidase	NA	NA	NA	NA
WP_165106097.1\|566880_567570_-	urea ABC transporter ATP-binding subunit UrtE	G9BWD6	Planktothrix_phage	5.9e-18	29.6
WP_165106647.1\|567584_568340_-	urea ABC transporter ATP-binding protein UrtD	A0A2H4PQG7	Staphylococcus_phage	4.1e-20	30.6
WP_165106099.1\|568384_569419_-	urea ABC transporter permease subunit UrtC	NA	NA	NA	NA
WP_165106649.1\|569415_570300_-	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_165106102.1\|570334_571525_-	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165106104.1\|572030_572216_-	hypothetical protein	NA	NA	NA	NA
WP_165106108.1\|574181_574481_-	hypothetical protein	NA	NA	NA	NA
WP_165089859.1\|574494_575577_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165106652.1\|575742_576309_+\|transposase	transposase	NA	NA	NA	NA
WP_165106112.1\|576443_576791_+	hypothetical protein	NA	NA	NA	NA
WP_165106115.1\|577260_577716_+	hypothetical protein	NA	NA	NA	NA
WP_165106119.1\|577868_579026_-	hypothetical protein	NA	NA	NA	NA
WP_165106132.1\|581125_582448_+	diguanylate cyclase	G3MA91	Bacillus_virus	3.0e-26	39.0
WP_165106136.1\|585355_585790_+	hypothetical protein	NA	NA	NA	NA
WP_165106146.1\|585936_586218_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_165106149.1\|586554_587100_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_165106654.1\|587027_587543_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_165106152.1\|587535_587961_+	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_165106155.1\|588011_588236_-	hypothetical protein	NA	NA	NA	NA
WP_165106158.1\|589352_590363_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_165106161.1\|591921_592773_-	formate/nitrite transporter family protein	E7DYY8	Enterobacteria_phage	2.7e-44	41.2
WP_165106163.1\|593294_593795_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_165106166.1\|593829_594369_-	DUF4142 domain-containing protein	NA	NA	NA	NA
WP_165106168.1\|596377_596536_-	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_165106170.1\|596757_597330_+	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_165106172.1\|597344_598016_+	HAD family hydrolase	NA	NA	NA	NA
WP_165106174.1\|598324_599494_-	glutathione-dependent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_165106177.1\|600063_600216_-	hypothetical protein	NA	NA	NA	NA
WP_165106179.1\|600267_600570_-	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_165106656.1\|601795_602092_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_165106182.1\|602424_604035_-	hypothetical protein	NA	NA	NA	NA
WP_165106184.1\|605284_606394_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165092202.1\|607695_609354_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.7e-167	55.5
WP_165092202.1\|610724_612383_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	3.7e-167	55.5
WP_165106187.1\|613163_614318_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165106191.1\|614435_615395_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.4e-62	43.4
WP_165106195.1\|615569_616745_+\|transposase	transposase	NA	NA	NA	NA
WP_165106198.1\|617607_618126_+	hypothetical protein	NA	NA	NA	NA
WP_165106201.1\|618312_618873_-	hypothetical protein	NA	NA	NA	NA
WP_165106659.1\|619054_619246_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_165105014.1\|619157_619631_+	hypothetical protein	NA	NA	NA	NA
WP_165106205.1\|619764_620286_-	hypothetical protein	NA	NA	NA	NA
WP_165106208.1\|620880_622017_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_165106211.1\|622385_622859_+	hypothetical protein	NA	NA	NA	NA
WP_165106215.1\|623386_623821_+	hypothetical protein	NA	NA	NA	NA
WP_165106661.1\|625616_626792_-	response regulator	A0A1B1IUJ1	uncultured_Mediterranean_phage	5.0e-09	27.8
WP_165106218.1\|630438_630705_-	hypothetical protein	NA	NA	NA	NA
WP_165106220.1\|631171_631654_+	hypothetical protein	NA	NA	NA	NA
WP_165106222.1\|631718_632843_-	sensor histidine kinase	NA	NA	NA	NA
WP_165103986.1\|633238_633499_+	hypothetical protein	NA	NA	NA	NA
WP_165103984.1\|633569_635159_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.7e-151	54.9
WP_165103982.1\|635189_635537_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	1.2e-43	68.7
WP_165103980.1\|635533_635974_-\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	2.0e-19	45.6
WP_165106225.1\|636005_636299_-	hypothetical protein	NA	NA	NA	NA
WP_165106227.1\|638114_641234_-	EAL domain-containing protein	G3MA91	Bacillus_virus	1.0e-24	39.2
WP_165106230.1\|641362_643153_-	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.5e-14	39.4
WP_165106232.1\|643425_644604_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_165106664.1\|645177_645510_+	phosphonate transporter	NA	NA	NA	NA
WP_165106235.1\|645509_646796_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	9.3e-17	34.3
WP_165106237.1\|646926_647721_+	EAL domain-containing protein	NA	NA	NA	NA
WP_165106240.1\|647878_649120_-	AMP-binding protein	NA	NA	NA	NA
WP_165106666.1\|649125_649509_-	photoactive yellow protein	NA	NA	NA	NA
WP_165106243.1\|650386_651514_-	HAMP domain-containing histidine kinase	A0A1B0VMK3	Pseudomonas_phage	9.5e-66	40.1
WP_165106245.1\|652061_653114_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_165105635.1\|653166_653943_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.1e-31	36.5
WP_165098394.1\|654155_654944_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.0e-37	36.6
WP_165106248.1\|654952_656476_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_165106669.1\|658140_658905_+	NAD(P)-dependent oxidoreductase	A0A1V0SKV4	Klosneuvirus	9.8e-06	36.1
WP_165105916.1\|659061_660216_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105916.1\|660799_661954_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165105916.1\|662537_663692_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_165106251.1\|665293_666517_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_165103980.1\|667533_667974_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	2.0e-19	45.6
WP_165103982.1\|667970_668318_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	1.2e-43	68.7
WP_165103984.1\|668348_669938_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	2.7e-151	54.9
WP_165103986.1\|670008_670269_-	hypothetical protein	NA	NA	NA	NA
WP_165106680.1\|671886_672273_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

747138 : 771649

uncultured_Caudovirales_phage(66.67%)

integrase,transposase

attL 746223:746238|attR 775107:775122

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
746223:746238	attL	NA	NA	NA	NA
WP_165093839.1\|747138_748350_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_165106406.1\|748496_748979_+	hypothetical protein	NA	NA	NA	NA
WP_165106408.1\|749066_749414_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_165106410.1\|749511_750129_+	hypothetical protein	NA	NA	NA	NA
WP_165106413.1\|750196_750898_-	AIM24 family protein	NA	NA	NA	NA
WP_165106714.1\|750993_751350_-	hypothetical protein	NA	NA	NA	NA
WP_165106415.1\|751518_752106_-	hypothetical protein	NA	NA	NA	NA
WP_165106418.1\|752140_752716_-	hypothetical protein	NA	NA	NA	NA
WP_165106421.1\|753422_753920_-	hypothetical protein	NA	NA	NA	NA
WP_165106424.1\|753937_754576_-	hypothetical protein	NA	NA	NA	NA
WP_165106427.1\|755324_756515_+	hypothetical protein	NA	NA	NA	NA
WP_165106429.1\|756553_757213_+	hypothetical protein	NA	NA	NA	NA
WP_165106432.1\|757202_757667_+	hypothetical protein	NA	NA	NA	NA
WP_165106435.1\|757711_758872_+	hypothetical protein	NA	NA	NA	NA
WP_165106437.1\|758862_759969_+	hypothetical protein	NA	NA	NA	NA
WP_165106440.1\|760020_760689_+	hypothetical protein	NA	NA	NA	NA
WP_165106442.1\|761235_763188_+	cell wall anchor protein	NA	NA	NA	NA
WP_165106716.1\|763672_764551_+\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJJ6	Virus_Rctr41k	4.6e-23	26.8
WP_165106719.1\|764684_766133_+\|integrase	site-specific integrase	A0A2H4J165	uncultured_Caudovirales_phage	1.1e-34	29.3
WP_165106446.1\|766129_768010_+\|integrase	integrase	A0A2H4J9J6	uncultured_Caudovirales_phage	8.6e-19	24.9
WP_165106449.1\|768006_769893_+\|integrase	integrase	NA	NA	NA	NA
WP_165106452.1\|769889_770252_+	hypothetical protein	NA	NA	NA	NA
WP_165106722.1\|770458_771649_+\|transposase	IS91 family transposase	NA	NA	NA	NA
775107:775122	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NZ_CP049316

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049316_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049316_1

116937-118436

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CRISPRCasFinder
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CRT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	PILER-CR

22 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP049316_1

>merge|NZ_CP049316|1|116937-118436|CRISPRCasFinder,CRT,PILER-CR
TTTTCGATCCGCGCGCCCGTGAAGAGCGCGACCCGGCTGGATACTTGCCGACCCGGATCGGGATCCCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACTGTTTGATGCGCTTGTGCGGTCCAGCCGGCAGTAGTTTCAATCCACGCGCCCGTGAAGAGCGCGACCGCGGTCGAACCGCCGCACAAGACGCCTTCCTGATAGTTTCAATCCACGCGCCCGTGAAGAGCGCGACATAGCGACGAGTGAATAACGCTTTCGTCTTTCTTTGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGAGTCGGCAACTGGTAATAGGTAAACGATACGCCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGACCGCATAGCAGCGTATTTCGCTGGCGTTTCCCAAGTTTCAATCCACGCGCCCGTGAAGAGCGCGACCAAATGCACCATCTTGCAGAGCCACGCGAGCACCGGTTTCAATCCACGCGCCCGTGAAGAGCGCGACCCGCCACCAGGTCTTTCATTTTTTCGAGCATGTGTTTCAATCCACGCGCCCGTGAAGAGCGCGACACCGGAAAAATGCGAGGTCTCATACAGCCTACGCGGTTTCAATCCACGCGCCCGTGAAGAGCGCGACCGCTATTTCCTCCGGCGGGTCGTCCGTCACTGCCGCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACACCTGCCAACGCCGTGGCAGGTACTGCCGGCTGAGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGATCGGACGTGACGATTTCGTCGCTATGGTCGCAGTTTCAATCCACGCGCCCGTGAAGAGCGCGACTTGCCATTGAAAATCCCTAGCGTAAATACGGTGACGGTTTCAATCCACGCGCCCGTGAAGAGCGCGACATGTCGCCGTATGCGCCGTCGAGCGTGTCGTACCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACCAGTGGTACATGCTTATCTCCTTTTTGGCAGGCCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACATTACGTGTGCGCGCCGGTATCGTGGAACACCGTCGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGTATTGTGCGACGCCGACGCCCGCTTCATATTGGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGACGAATTTGTCGGTATGGCGACGATCGGTTCGTGGGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGAAAGGAAGCCATAGCCCAGCGAAGTCGGTGCGACGTTTCAATCCACGCGCCCGTGAAGAGCGCGACTGGCCAGCGCGCCGGCCGGGGCTGTTCCGTAAGCGTGTTTCAATCCACGCGCCCGTGAAGAGCGCGACGCCGGCTGAGCAGCGGCGTGTTGGTAAGGCGTTGTTTCAATCCACGCGCCCGTGAAGAGCGCGACAATCGATATCGCGTTAGCGCGTATCAAGCCAATATGTTTCAATCCACGCGCCCGTGAAGAGCGCGAC

>NZ_CP049316|1|1|116937-118436|CRISPRCasFinder
TTTTCGATCCGCGCGCCCGTGAAGAGCGCGAC	CCGGCTGGATACTTGCCGACCCGGATCGGGATCCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TGTTTGATGCGCTTGTGCGGTCCAGCCGGCAGTA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CGCGGTCGAACCGCCGCACAAGACGCCTTCCTGATA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATAGCGACGAGTGAATAACGCTTTCGTCTTTCTTT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GAGTCGGCAACTGGTAATAGGTAAACGATACGCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GACCGCATAGCAGCGTATTTCGCTGGCGTTTCCCAA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CAAATGCACCATCTTGCAGAGCCACGCGAGCACCG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CCGCCACCAGGTCTTTCATTTTTTCGAGCATGT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ACCGGAAAAATGCGAGGTCTCATACAGCCTACGCG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CGCTATTTCCTCCGGCGGGTCGTCCGTCACTGCCGC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ACCTGCCAACGCCGTGGCAGGTACTGCCGGCTGA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GATCGGACGTGACGATTTCGTCGCTATGGTCGCA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TTGCCATTGAAAATCCCTAGCGTAAATACGGTGACG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATGTCGCCGTATGCGCCGTCGAGCGTGTCGTACC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CAGTGGTACATGCTTATCTCCTTTTTGGCAGGCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATTACGTGTGCGCGCCGGTATCGTGGAACACCGTC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GTATTGTGCGACGCCGACGCCCGCTTCATATTG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GACGAATTTGTCGGTATGGCGACGATCGGTTCGTGG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GAAAGGAAGCCATAGCCCAGCGAAGTCGGTGCGAC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TGGCCAGCGCGCCGGCCGGGGCTGTTCCGTAAGCGT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GCCGGCTGAGCAGCGGCGTGTTGGTAAGGCGTT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	AATCGATATCGCGTTAGCGCGTATCAAGCCAATAT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC

>NZ_CP049316|1|1|116937-118436|CRT
TTTTCGATCCGCGCGCCCGTGAAGAGCGCGAC	CCGGCTGGATACTTGCCGACCCGGATCGGGATCCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TGTTTGATGCGCTTGTGCGGTCCAGCCGGCAGTA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CGCGGTCGAACCGCCGCACAAGACGCCTTCCTGATA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATAGCGACGAGTGAATAACGCTTTCGTCTTTCTTT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GAGTCGGCAACTGGTAATAGGTAAACGATACGCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GACCGCATAGCAGCGTATTTCGCTGGCGTTTCCCAA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CAAATGCACCATCTTGCAGAGCCACGCGAGCACCG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CCGCCACCAGGTCTTTCATTTTTTCGAGCATGT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ACCGGAAAAATGCGAGGTCTCATACAGCCTACGCG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CGCTATTTCCTCCGGCGGGTCGTCCGTCACTGCCGC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ACCTGCCAACGCCGTGGCAGGTACTGCCGGCTGA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GATCGGACGTGACGATTTCGTCGCTATGGTCGCA
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TTGCCATTGAAAATCCCTAGCGTAAATACGGTGACG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATGTCGCCGTATGCGCCGTCGAGCGTGTCGTACC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	CAGTGGTACATGCTTATCTCCTTTTTGGCAGGCC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	ATTACGTGTGCGCGCCGGTATCGTGGAACACCGTC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GTATTGTGCGACGCCGACGCCCGCTTCATATTG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GACGAATTTGTCGGTATGGCGACGATCGGTTCGTGG
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GAAAGGAAGCCATAGCCCAGCGAAGTCGGTGCGAC
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	TGGCCAGCGCGCCGGCCGGGGCTGTTCCGTAAGCGT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	GCCGGCTGAGCAGCGGCGTGTTGGTAAGGCGTT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC	AATCGATATCGCGTTAGCGCGTATCAAGCCAATAT
GTTTCAATCCACGCGCCCGTGAAGAGCGCGAC

>NZ_CP049316|1|1|116938-118436|PILER-CR
TTTCGATCCGCGCGCCCGTGAAGAGCGCGACC	CGGCTGGATACTTGCCGACCCGGATCGGGATCCCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACT	GTTTGATGCGCTTGTGCGGTCCAGCCGGCAGTAG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACC	GCGGTCGAACCGCCGCACAAGACGCCTTCCTGATAG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	TAGCGACGAGTGAATAACGCTTTCGTCTTTCTTTG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	AGTCGGCAACTGGTAATAGGTAAACGATACGCCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	ACCGCATAGCAGCGTATTTCGCTGGCGTTTCCCAAG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACC	AAATGCACCATCTTGCAGAGCCACGCGAGCACCGG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACC	CGCCACCAGGTCTTTCATTTTTTCGAGCATGTG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	CCGGAAAAATGCGAGGTCTCATACAGCCTACGCGG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACC	GCTATTTCCTCCGGCGGGTCGTCCGTCACTGCCGCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	CCTGCCAACGCCGTGGCAGGTACTGCCGGCTGAG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	ATCGGACGTGACGATTTCGTCGCTATGGTCGCAG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACT	TGCCATTGAAAATCCCTAGCGTAAATACGGTGACGG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	TGTCGCCGTATGCGCCGTCGAGCGTGTCGTACCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACC	AGTGGTACATGCTTATCTCCTTTTTGGCAGGCCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	TTACGTGTGCGCGCCGGTATCGTGGAACACCGTCG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	TATTGTGCGACGCCGACGCCCGCTTCATATTGG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	ACGAATTTGTCGGTATGGCGACGATCGGTTCGTGGG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	AAAGGAAGCCATAGCCCAGCGAAGTCGGTGCGACG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACT	GGCCAGCGCGCCGGCCGGGGCTGTTCCGTAAGCGTG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACG	CCGGCTGAGCAGCGGCGTGTTGGTAAGGCGTTG
TTTCAATCCACGCGCCCGTGAAGAGCGCGACA	ATCGATATCGCGTTAGCGCGTATCAAGCCAATATG
TTTCAATCCACGCGCCCGTGAAGAGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049316.1\|WP_165085506.1\|120623_121496_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_CP049316.1\|WP_165085471.1\|106500_107631_+\|PAAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|269829
NZ_CP049316.1\|WP_165085488.1\|113226_114438_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|226082
NZ_CP049316.1\|WP_165085479.1\|108994_111418_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NZ_CP049316.1\|WP_165085503.1\|119974_120619_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NZ_CP049316.1\|WP_165085511.1\|123303_123978_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP049316.1\|WP_165085514.1\|130541_131606_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|236974
NZ_CP049316.1\|WP_165085498.1\|118630_118921_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP049316.1\|WP_165085490.1\|114428_114956_+\|carbon-monoxide-dehydrogenase-subunit-G	unknown	unknown	gnl\|CDD\|176853
NZ_CP049316.1\|WP_165085512.1\|124064_126281_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP049316.1\|WP_165092999.1\|129585_130266_-\|peptidase	unknown	unknown	gnl\|CDD\|225832
NZ_CP049316.1\|WP_165085484.1\|112332_113220_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NZ_CP049316.1\|WP_165085501.1\|118931_119972_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP049316.1\|WP_165085477.1\|108427_108904_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NZ_CP049316.1\|WP_165085513.1\|128366_129488_+\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|377164
NZ_CP049316.1\|WP_165085509.1\|121492_123307_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP049316.1\|WP_165085492.1\|114928_115948_+\|XdhC-family-protein	unknown	unknown	gnl\|CDD\|224886
NZ_CP049316.1\|WP_165085495.1\|116005_116755_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224137
NZ_CP049316.1\|WP_165085482.1\|111430_112231_+\|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl\|CDD\|224238
NZ_CP049316.1\|WP_165085474.1\|107627_108242_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP049316.1\|WP_165085506.1\|120623_121496_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.87021e-153
NZ_CP049316.1\|WP_165085471.1\|106500_107631_+\|PAAR-domain-containing-protein	gnl\|CDD\|269829	cd14744, PAAR_CT_2, proline-alanine-alanine-arginine (PAAR) domain with uncharacterized C-terminal extension. This domain is found in the PAAR (proline-alanine-alanine-arginine) repeat family of mostly beta- and gamma-proteobacteria, and forms a sharp conical extension on the VgrG spike, a trimeric protein complex of the bacterial type VI secretion system (T6SS). Most members contain C-terminal domain extensions corresponding to several uncharacterized domains such as S-type pyocin, DUF2235, DUF2345 and cytotoxic proteins. However, these terminal domains are exposed to solution, and do not distort the binding site of VgrG. The pointed tip of the PAAR domain is stabilized by a zinc atom positioned close to the cone's vertex and is likely to be important for its integrity during penetration of the target cell envelope. VgrG proteins are orthologous to the central baseplate spikes of bacteriophages with contractile tails, and genes encoding proteins with PAAR motifs have been frequently found immediately downstream from vgrG-like genes.	3.9174e-17
NZ_CP049316.1\|WP_165085488.1\|113226_114438_+\|VWA-domain-containing-protein	gnl\|CDD\|226082	COG3552, CoxE, Protein containing von Willebrand factor type A (vWA) domain [General function prediction only].	3.36733e-119
NZ_CP049316.1\|WP_165085479.1\|108994_111418_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
NZ_CP049316.1\|WP_165085503.1\|119974_120619_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.37585e-41
NZ_CP049316.1\|WP_165085511.1\|123303_123978_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	8.12568e-111
NZ_CP049316.1\|WP_165085514.1\|130541_131606_-\|serine/threonine-protein-kinase	gnl\|CDD\|236974	PRK11768, PRK11768, serine/threonine protein kinase.	0
NZ_CP049316.1\|WP_165085498.1\|118630_118921_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.29359e-31
NZ_CP049316.1\|WP_165085490.1\|114428_114956_+\|carbon-monoxide-dehydrogenase-subunit-G	gnl\|CDD\|176853	cd05018, CoxG, Carbon monoxide dehydrogenase subunit G (CoxG). CoxG has been shown, in Oligotropha carboxidovorans, to anchor the carbon monoxide (CO) dehydrogenase to the cytoplasmic membrane. The gene encoding CoxG is part of the Cox cluster (coxBCMSLDEFGHIK) located on a low-copy-number, circular, megaplasmid pHCG3. This cluster includes genes encoding subunits of CO dehydrogenase and several accessory components involved in the utilization of CO. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	2.1414e-59
NZ_CP049316.1\|WP_165085512.1\|124064_126281_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.00056e-54
NZ_CP049316.1\|WP_165092999.1\|129585_130266_-\|peptidase	gnl\|CDD\|225832	COG3295, COG3295, Uncharacterized protein conserved in bacteria [Function unknown].	1.87679e-33
NZ_CP049316.1\|WP_165085484.1\|112332_113220_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.64776e-44
NZ_CP049316.1\|WP_165085501.1\|118931_119972_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP049316.1\|WP_165085477.1\|108427_108904_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	2.83774e-78
NZ_CP049316.1\|WP_165085513.1\|128366_129488_+\|PepSY-domain-containing-protein	gnl\|CDD\|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.99797e-55
NZ_CP049316.1\|WP_165085492.1\|114928_115948_+\|XdhC-family-protein	gnl\|CDD\|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	1.27596e-77
NZ_CP049316.1\|WP_165085495.1\|116005_116755_-\|hypothetical-protein	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.42346e-05
NZ_CP049316.1\|WP_165085482.1\|111430_112231_+\|xanthine-dehydrogenase-family-protein-subunit-M	gnl\|CDD\|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	1.05354e-76
NZ_CP049316.1\|WP_165085509.1\|121492_123307_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0

>NZ_CP049316.1|WP_165085495.1|116005_116755_-|hypothetical-protein
MSNHHVLICLPTYSEEVHINFAFSLLDLTRALTKSGSSYETLHVASSHIIRARNFFANYFLSRPEFTHLLFLDTDMKFPAEAVIKLLAANKAVAGVAYPFRRIDLNGPISAADTGLTLREWLEKHSEYTIAPIPDANGDVRFVDGFVQARHIGTGVFLAQREAFEATKPFSECYAPPKQYESMLTNGKFYGFFETIEEDGLYQGEDVSFCTRARQAGLTIWGLIDQTVVHYGASEVSGQYLQAMRRKEK
>NZ_CP049316.1|WP_165085492.1|114928_115948_+|XdhC-family-protein
MDSVDLEVLRNSARWLERGHRVLLVTVVKTWGSSPRPEGAMLAVRDDGAVMGSVSGGCIEDDLIERVRQRGIEQTKPESVKYGISAEEAHRFGLPCGGTIQLVLEPLSMASGIAELCDAVLAGRLVTRTLDMANGAVKLEPAQATDGVTFDETTLSTIHGPRYRMLVIGAGQLSRYLCSIAVGLDYHVTVCDPREEYTDEWDVPGTKIVRTMPDDTVMDMKLDERCAVIALTHDPKLDDLALMEALKTPAFYVGALGSRKNNAARRERLKEFDLSDAELSRLHGPVGIYIGSRTPPEIAVSILAEVTAAKNGVSLPTILQVEGAKAARELEGTGEVCGI
>NZ_CP049316.1|WP_165085490.1|114428_114956_+|carbon-monoxide-dehydrogenase-subunit-G
MELTETHNLPVPQDIAWQALNDTEILRACIPGCESIEADGENAYAVAMTASVGPVKAKFKGRMNLVDIDAPHTYTIVFEGQGGTAGFGKGQAKVNLEPGDNADSTTLSYTANAQVGGKLAQIGSRLVDGAARKIAGEFFKRFSAQLTQGDEPGSAGDEGEEKKGKRSWTAWISKS
>NZ_CP049316.1|WP_165085488.1|113226_114438_+|VWA-domain-containing-protein
MEKIETPTLAHNVVHFVRLLRGAGLAMSPAHSVDALEALRWIDITRRDDVRAALAALLVHAPDERELFHQAFDLFWRDPDWEGKLRALLLPKVTSGAPPPKRNNRLADALAARAAALKPENKQSDNVEHVHARFTFSAQERLSHRDFDTLTSDEWRALRHQIRSHRMPLATEPTRRLKTASHGTHADLRASARSAVRSGGDWTTWKYKKVIERRPPLVLLLDISGSMSAYSRAVLYFCHALLQSRERLQVFLFGTRLTNATRALRERDPDVAIAAISDQVVDWSGGTRIGAALAEFNRRWARRVLSGRATVLFVTDGLDHEAIDVLETEMQRLRRFAHRLVWLNPLLRYTDFTPRARGVRAILPHVDAMLAAHNLDSLNAVGRELAAVTRRADRKSAGDTSWN
>NZ_CP049316.1|WP_165085484.1|112332_113220_+|MoxR-family-ATPase
MDPASIDETLTALSGQQYFASRELATGLFLALKMQRPLFLEGEPGVGKTELAKAAAGMLGTQMLRLQCYEGLDTASALYEWDYPRQIMALRIAEAAGEQPSNDSLYKSEFLLKRPLLQALMPDPSNPGAQRVLLIDEIDRADEPFEAFLLELLSDFQVSIPEYGTVRAERPPLVVMTSNRTREVHDALKRRCLYQWIGYPARDVELQIVAARAPEASVDLQARAVAFVHRLRTLDLFKAPGVAETIDWCRALAALSVSELDPQSVQDTLGVLLKYQDDLARVDAAEIAQCLAAPA
>NZ_CP049316.1|WP_165085482.1|111430_112231_+|xanthine-dehydrogenase-family-protein-subunit-M
MYSFDYQRPDKSDAAVAFLKQHDDAKYLGGGQSLLPTMRLRLAQPSALVDVTRIGAMKDITVTGDKVTIGGAVCHAQVAANPEVQRALPGLADLAGHIGDRQVRERGTIGGSLANDDPAACYPAAVLALNATIVTDRRRITADDFFLGMYETALEPDELITSVEFPIAERAGYEKFRNPASHFALVGVFVAKHAGGVRVAITGAAACVFRASALEDALSKDFSVAAARGTSISADTLNEDMHASAEYRAHLIPILAGRAVDRANAF
>NZ_CP049316.1|WP_165085479.1|108994_111418_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MNAPETPDTHHMIGTAVRRKEDYRFLTGNGQYTDDVVLPQQTYGVFLRSPYAHATIRSIDITAAKAAPGVVAIFTGADMAGESVGGLPCGWLIHNIDGKPMNEPPHPVIAHTKVRHVGDQVALIVAESVKEAKDAIELIEVDYDVLPAVVDTATAADPGQPQVHDEAPNNLCYTWGHGDKAATDAAFAKAAHVTTLDIVNQRLVPNAIEPRAVNASYSKSDDSYTVYVANQNPHVERLLMAAFVLSLPESKLRIIAPDVGGGFGSKIYLYAEDVALTWASKKVRRPIKWTCERSEAFLSDAHGRDHVTKAELALDADGKFLGLRVHTTANMGAYLSTFASAIPTILYATLLAGQYATPAIYAEVKAVFTNTVPVDAYRGAGRPEATYVLERIVETAAREMNIDPAELRRRNFIRSWPYTTPVGLTYDSGDYSALLDRAMQIADVEGFPARREESKKNGKLRGLGYSCYIEACGLAPSNLAGALGARAGLFEAGEIRVHPTGSVTVFTGAHSHGQGHETTFAQVVADRLGVSMDNIEIVHGDTGRIPFGMGTYGSRSIAVGGSAIMKALDKIEDKAKKIAAHLLEASAEDIEFKDGIFRVAGTDRTKAFAEVSLAAYVPHNFPLDKLEPGLNENAFYDPSNFTYPSGAYLCEVEVDQDTGETRIQKFTAVDDFGNIINPMIVEGQVHGGIGQGIGQAMLERAVYDNESGQLMSGSFMDYAMPHASDLPNFDVETAKGTPCVHNPLGVKGCGEAGAIGSPPAVINAIIDALSPLGVTDLQMPATPHRVWAAMHAAADASAARGASTPAA
>NZ_CP049316.1|WP_165085477.1|108427_108904_+|(2Fe-2S)-binding-protein
MALSISLTVNGKAVTATVEPHILLVQFLREELRLTGTHIGCDTAQCGACTVHLDGRAIKSCNILAVQADGSSVTTIEGIAKDGELHPMQAAFKECHGLQCGFCTPGMVMSATSLAAQKPDLTEADVREQLDGNLCRCTGYHNIVKAIVQGAQAMKAAP
>NZ_CP049316.1|WP_165085474.1|107627_108242_+|hypothetical-protein
MTKLLGFITAVATTIALATGCSTKIEGKIMPKDFSLEGFQTATSSHPGTITFIESWNDVPKRKTADDYPDSFKFLCLDENEKEVSRDKAKWCIPIVEFDVFSVDDNGKSVPFIEASSISITAYGPDHRFVRSLSTAPRPPSPAAPVPKSGSAMPPNIGDASRTASSTNATPLKSAPSVPQSSGAVQDKTQTTFWERLKRTIRDI
>NZ_CP049316.1|WP_165085471.1|106500_107631_+|PAAR-domain-containing-protein
MRRNYLKVGDVATNGATIIEGIDKIKFGGVYLTYLYAKVRCPVCNTIGIIVPWGPRRPGKWMGKDPALHDDLCDCQCDPKPHLISSQSGMFMSFESHELAAMGFSPTGKLLQKSPLPGGLAEQTPVESTDSNPATGPSGQPATDCSYLDGSKSRIDAPAGFYVSRNAVSLSPGKPTQADFPAGGKADATQFEAKVDGKQIPIFVPTQPPTDGLPMIRERQLAKALEKLPSQNLENIGQITTNASPNPEDAIWQRDYGQPDFSSAATASLKQGIAFYPWPAWKGHSEIPQRYIDSTMLHETGHQVSEALWKDPAMKQRFEDAIASDGQAPSQYAGRNVNEDFAESGNMYWSSKGTPCEGEGRKRYPARFAYFDSLTK
>NZ_CP049316.1|WP_165085498.1|118630_118921_-|CRISPR-associated-endonuclease-Cas2
MMVLVSYDVATSTEGGTRRLRRVARACKDFGQRVQYSVFEIEVDAAQWTLLKRRLLTVIDPEVDSLRFYFLGNNWERRIEHVGAKEAVDFNAPLIV
>NZ_CP049316.1|WP_165085501.1|118931_119972_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRRQLNTLYVTTEGAWLKKDGANVVMEVEGDERARLPIHMLASVVCFGRVMISPPLLGFCVESGVSVAYLSMHGRFLARVEGPVSGNVLLRREQYRVSDDLVRAAPIVRNVVAGKIHNQRAVLSRALRDYGDGFTDDIRLELERAQKRLSIISRRLLSESDIDILRGLEGEAAQSYFGVFQHLVRVDDPAFKFSGRSRRPPLDAINAVLSFLYTLITHDCRSALETVGLDPAVGFLHRDRPGRPSLALDLIEEMRPVLADRLALSMINRKQLNKKDFRFLDNGACLLTETSRKALLVAYQERKRDEIAHPFLDEKIPLGMVPFVQAQLLARHLRGDLDAYPAFLWK
>NZ_CP049316.1|WP_165085503.1|119974_120619_-|CRISPR-associated-protein-Cas4
MTNSSQPDETIALSALQHYLFCARQCALIHVEQIWSENIFTAEGRVLHEQADKPLAESRRGVRTVTAMPLSNAELGIAGVADVVEFHRLEAERAERAYPVEYKRGKPKAHRADEVQLCAQALCLESMLKQSIGEGALFYGKTRRRRVVAIDAELRALTIGTIGAVRALVRDGRTPPARYEPHRCDSCSLIDDCRPQMLGRHLSAKAWFEAQLED
>NZ_CP049316.1|WP_165085506.1|120623_121496_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTILANRYEFVYLFDVTNGNPNGDPDAGNLPRLDPETNLGLVTDVCLKRKIRNYVTLEKDNKAGHAIYMQEKAVLNLQHKLGYAALNLVPVDKKLPKDPKDAEALTKWMCTNFFDVRAFGAVMSTGVNCGQVRGPIQLAFAKSIEPVTPMEISITRMSVTSEKDAENSDRTMGRKHILPYGLYRAHGFISAKLAERTGFTEDDLELVWRSLTNMFEHDRSAARGEMAARKLIVFKHESALGNAPAHTLFDAVKVERVKEGSDLPARFFSDYTVSIDKAKIASGVEVIDRI
>NZ_CP049316.1|WP_165085509.1|121492_123307_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MIFKSLVEYYERLALQGKVPPFGLTQEKIGYAFLLDHDGKLQDVINLSDPDDKKSKWKMMPVTASFKRPGSAPPSFFLWDKTAFVLGVEQKVGSDVPTLNLKSHASFKALHLDRLADSTDAGLVALRKFIEAWIPEQWAQCEQIVKHVPAIFSANIVFRLDGELSYIHERAAAQELIKRYSTTDEAAIGLCLVSGETRPIARLHPAIKGVWGAQSAGASIVSFNLDAFDSYGKERGANAPVSVHAAFAYTTVLNYLLLRDPHHQQCVQIGDASVVFWAEAKDQQKQEAAESLFFSALQPPPTDSAEAAKLKHALEAVSAGRGLNDLDANLDPKSKMFVLGLSPNASRLSVRYWFTESLGKFAKRLAQHYNDLTIEPTPWKTLPVAWRLLASIAAQEKTENVPPQLAGAVMRAVFSGGRYPRTLLSAAIMRMRADGDISGLRVALCKAVLTRDQRLDNNDNQQEVPVSLDRSNTTPGYLLGRLFSALESIQEAALHSVSASIKDRYYGSASAMPAGVFPALMRGAQNHLSKAMKDPKGKGLAISLEKEVQQIVDGLGCEFPKTLRLEDQGRFAIGYYHQRNERFRSKASKDEAAEITDDTLETTV
>NZ_CP049316.1|WP_165085511.1|123303_123978_-|type-I-C-CRISPR-associated-protein-Cas5
MAYGIRLLVKGERALFTRPEMKVERVSYDVITPSAARGIVEAIHWKPAIRWVIDRIQVLNEIRFDTIRRNEVASKIPGSSARSAMKKGTLEGLVNYVDEDRQQRAASILKDVAYVIEAHFVLTDKAEDGDSIGKHLDIFNRRARKGQCFQMPCFGVREFPADFTLLEDDERAHEPHESLIAQKDLGWMLHDIDFKNAMTPHFFRASIQNGWIDIPPLSFAERAA
>NZ_CP049316.1|WP_165085512.1|124064_126281_-|CRISPR-associated-helicase-Cas3'
MTRVFHAHSTPNPDESDWQTLPDHLNAVGELAGQSARHFGAARLAETAGKLHDLGKYTDAYQQRIRGGPRVDHATWGAKIACKQYGALGRLMAYGIAGHHAGLANGRDPGSRTALDGRLAADLPDLFNDYLKDLVLPTTAKEMEPTRWKQNAERPQFQLSMLTRMIFSCVVDGDYLDTDRFYAKTEDRPLDRDTPKPTLIELRAKLGAYLNAFAVVNPIDTTRALVLSHARSHAGDRIGMFSLTVPTGGGKTLTSLAFALDHAIAHGLDRVIFVIPFTSIVEQNAAVFKQAFGDLGDAAVLEHHSAFVPTPGENAEAAAKLRVVMDNWDAPVIVTTSVQFFESLYASKPSQCRKLHNIAGSVVILDEAQALPLKLLRPCVAVLDELALNYRTSVVLCTATQPALNAPEFPGGFKNVVELAPDPEALFETLARVTVKSAGTLDDPALTQRMRDHEQVLCIVNNRRHAQALYTSIAGENGARHLSTLMYPKHRTRVLNEVREMLKDKETCRLVSTSLIEAGVDIDFPYVMRAEAGLDSIAQAAGRCNRSGKRSRTESLVEVFAPENTDWAPPKALETLADKGREVMRTSAADPLSIAAINAYFNAVYWQTGPEKLDEHNLLGTIEDDGLKGFKFELIDQQFQMIDSVQMPAIIPGDAECKALLEELKDTKNCGCIARKLQPYLIQIPHEVYNALAASRAIQPVAEHKYGTQFMQLIMMNLYTERFGLKLDGSIDPDSLIH
>NZ_CP049316.1|WP_165085513.1|128366_129488_+|PepSY-domain-containing-protein
MLSSRSLRIWSFVHRWTSIVCTAFMLLLCLTGLPLVFGHELDVLLGDAIEAPELPAHQSNARASYDAILNSALAKNPGHVPQYMIWEPDESMLPIVVTAPRPDTPPDDTQSTTIDARTARALGAPPGKGSLKFILLKLHVDMFAGLPGKLFLGAMGVSFVVAIVSGVVVYLPFWKKVGLGRVRIKKSRRIAWLDGHNALGMLTLVWALLVGATGSINTLADLLLDAWRNDQLAQMLAPYQGKPPVKATASVDEAIKIARDKTPSMIPSFVAFPGTRFSSPHHYTVFMRGDGILTTRMLRPVLIDAETGKLTDSRELPWYLTLLLGSQPLHFGDFGGMPLKIFWAAFDVLTIVVLGSGLYIWLSRGNKNKRKPA
>NZ_CP049316.1|WP_165092999.1|129585_130266_-|peptidase
MPYAPRGGRLIDDAEQFTRKQRSRRATFIKWLRKVHGWVGLWGAVLGLLFGTTGFLLNHRAGPLKISSGEPQVSQMQMAVPAHGLKSPMELGKWLKQELKLDGNIGRPKREAAHPVGWGDQKTMQPELWTVAVASPGGSVSAEYWVGNGFVSVKKSENSFLATMTNLHKGVGLSMGWVLLIDTLAGSIILLSLTGVLLWTELNKRKTVGAVIVMASIVAMVCMGLM
>NZ_CP049316.1|WP_165085514.1|130541_131606_-|serine/threonine-protein-kinase
MNSNHSDASRASADSLSFSGDDANLPPPPFADLTPERVLDALDSVLMPLGERTDGGMLALNSYENRVYQVGMEDGPPMVAKFYRPLRWSDDAILEEHAFVSTLYEREIPAVPARVLNGASLHTFDGFRFSIFERRGGRAPDIDRPDTLEWLGRFIGRIHAVGQIKPYVERPALDIQTFGYEPREFLLTHGFVPKDVLEAYETVVKMALEGVERCYERAGDVKSIRLHGDCHPSNVLWTDAGPHFVDFDDSRMAPAIQDLWLLLPGDRPEASRALGDLLAGYEDFCDFEPRELHLVEALRTLRLIHYAAWLARRWNDPAFPAAFPWFNTQRYWEDRILELREQVGAMEEGPLWPV

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Crispr_ID: NZ_CP049316_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049316_2

126435-127864

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CRISPRCasFinder
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CRT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	PILER-CR

21 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP049316_2

>merge|NZ_CP049316|2|126435-127864|CRISPRCasFinder,CRT,PILER-CR
GTTTTGATCAACGCGCACGTGAGAGGTGCGACGAGGCTGTTTTAGAAAAGCGGGTTTTGGAGATTATGTTTCAATCCACGCGCCCGTGAAGGGCGCGACCTGTCGCCGTCCACCAGCACGGGGTTCGTCCAGCCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACCAGACTCGTTACGTCGGGTCGTTGACCGGGCTTCAGTTTCAATCCACGCGCCCGTGAAGGGCGCGACCTGAGCATAAACCTTTATTCGGTCACGTCTCCGGGGTTTCAATCCACGCGCCCGTGAAGGGCGCGACCGCGCAAACTCGAAGAGTTTGGACTGTATGTCGTGTCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACTATACGCCGTGCCGTCCTCAGTAATCAGATAGGTCTCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACTCCCCGGTCAATACGCGCCTGTCATGGTGATGGAGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGGCGTGACAGCGTCAAGTATTTGGAAATTCGATGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGCTACCAACGTGACACCGTTGATAACAACCGTAGTTTCAATCCACGCGCCCGTGAAGGGCGCGACACCAATCATGCCCGACTCTGCCGACAGTACATGCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACACTTGCCAAGTGTCGTTTCGGTTTCACTTGTTGGTTTCAATCCACGCGCCCGTGAAGGGCGCGACATCCTTGAGTACAGCAGCGTGTTCCATGACTTCGAGTTTCAATCCACGCGCCCGTGAAGGGCGCGACCAAGCTGAACATGCACGCGGGCGTGATCGAAGAGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGTCGCCGATCAGCGCGTCCGGTCGGAGCTGCTCGGCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGTTAAGCGGATGTTCGAACCACGCCATCTGCACTTGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGCAGAGGTACACGACGTGTCGACCTAGCTTTTTGTGTTTCAATCCACGCGCCCGTGAAGGGCGCGACTGGTGAGCTCGACGATGGCGTCGGCCAAGGTGCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACTGAGCGGGGCCGCTGGCATCACGATCGAAAAGCTTGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGTTCGACCCACAAGAATCCGTCCTTTACCTGATCGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGTACGGCATCCTGACGGGCAATCCGAAGATGGCTGGTTTCAATCCACGCGCCCGTGAAGGGCGCGACGATACTCGTTAGAACGCCGCACCATGATTATCTCGTTTCAATCCACGCGCCCGTGAAGGGCGCGAC

>NZ_CP049316|2|2|126435-127864|CRISPRCasFinder
GTTTTGATCAACGCGCACGTGAGAGGTGCGAC	GAGGCTGTTTTAGAAAAGCGGGTTTTGGAGATTAT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGTCGCCGTCCACCAGCACGGGGTTCGTCCAGCC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAGACTCGTTACGTCGGGTCGTTGACCGGGCTTCA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGAGCATAAACCTTTATTCGGTCACGTCTCCGGG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CGCGCAAACTCGAAGAGTTTGGACTGTATGTCGTGTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TATACGCCGTGCCGTCCTCAGTAATCAGATAGGTCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TCCCCGGTCAATACGCGCCTGTCATGGTGATGGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GGCGTGACAGCGTCAAGTATTTGGAAATTCGAT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCTACCAACGTGACACCGTTGATAACAACCGTA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACCAATCATGCCCGACTCTGCCGACAGTACATGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACTTGCCAAGTGTCGTTTCGGTTTCACTTGTTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ATCCTTGAGTACAGCAGCGTGTTCCATGACTTCGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAAGCTGAACATGCACGCGGGCGTGATCGAAGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTCGCCGATCAGCGCGTCCGGTCGGAGCTGCTCGGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTAAGCGGATGTTCGAACCACGCCATCTGCACTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCAGAGGTACACGACGTGTCGACCTAGCTTTTTGT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGGTGAGCTCGACGATGGCGTCGGCCAAGGTGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGAGCGGGGCCGCTGGCATCACGATCGAAAAGCTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTCGACCCACAAGAATCCGTCCTTTACCTGATC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTACGGCATCCTGACGGGCAATCCGAAGATGGCTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GATACTCGTTAGAACGCCGCACCATGATTATCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC

>NZ_CP049316|2|2|126435-127864|CRT
GTTTTGATCAACGCGCACGTGAGAGGTGCGAC	GAGGCTGTTTTAGAAAAGCGGGTTTTGGAGATTAT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGTCGCCGTCCACCAGCACGGGGTTCGTCCAGCC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAGACTCGTTACGTCGGGTCGTTGACCGGGCTTCA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGAGCATAAACCTTTATTCGGTCACGTCTCCGGG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CGCGCAAACTCGAAGAGTTTGGACTGTATGTCGTGTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TATACGCCGTGCCGTCCTCAGTAATCAGATAGGTCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TCCCCGGTCAATACGCGCCTGTCATGGTGATGGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GGCGTGACAGCGTCAAGTATTTGGAAATTCGAT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCTACCAACGTGACACCGTTGATAACAACCGTA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACCAATCATGCCCGACTCTGCCGACAGTACATGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACTTGCCAAGTGTCGTTTCGGTTTCACTTGTTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ATCCTTGAGTACAGCAGCGTGTTCCATGACTTCGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAAGCTGAACATGCACGCGGGCGTGATCGAAGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTCGCCGATCAGCGCGTCCGGTCGGAGCTGCTCGGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTAAGCGGATGTTCGAACCACGCCATCTGCACTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCAGAGGTACACGACGTGTCGACCTAGCTTTTTGT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGGTGAGCTCGACGATGGCGTCGGCCAAGGTGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGAGCGGGGCCGCTGGCATCACGATCGAAAAGCTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTCGACCCACAAGAATCCGTCCTTTACCTGATC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTACGGCATCCTGACGGGCAATCCGAAGATGGCTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GATACTCGTTAGAACGCCGCACCATGATTATCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC

>NZ_CP049316|2|2|126502-127864|PILER-CR
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGTCGCCGTCCACCAGCACGGGGTTCGTCCAGCC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAGACTCGTTACGTCGGGTCGTTGACCGGGCTTCA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CTGAGCATAAACCTTTATTCGGTCACGTCTCCGGG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CGCGCAAACTCGAAGAGTTTGGACTGTATGTCGTGTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TATACGCCGTGCCGTCCTCAGTAATCAGATAGGTCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TCCCCGGTCAATACGCGCCTGTCATGGTGATGGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GGCGTGACAGCGTCAAGTATTTGGAAATTCGAT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCTACCAACGTGACACCGTTGATAACAACCGTA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACCAATCATGCCCGACTCTGCCGACAGTACATGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ACTTGCCAAGTGTCGTTTCGGTTTCACTTGTTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	ATCCTTGAGTACAGCAGCGTGTTCCATGACTTCGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	CAAGCTGAACATGCACGCGGGCGTGATCGAAGA
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTCGCCGATCAGCGCGTCCGGTCGGAGCTGCTCGGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTAAGCGGATGTTCGAACCACGCCATCTGCACTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GCAGAGGTACACGACGTGTCGACCTAGCTTTTTGT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGGTGAGCTCGACGATGGCGTCGGCCAAGGTGC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	TGAGCGGGGCCGCTGGCATCACGATCGAAAAGCTT
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTTCGACCCACAAGAATCCGTCCTTTACCTGATC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GTACGGCATCCTGACGGGCAATCCGAAGATGGCTG
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC	GATACTCGTTAGAACGCCGCACCATGATTATCTC
GTTTCAATCCACGCGCCCGTGAAGGGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049316.1\|WP_165085506.1\|120623_121496_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NZ_CP049316.1\|WP_165085516.1\|132235_133492_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP049316.1\|WP_165085509.1\|121492_123307_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NZ_CP049316.1\|WP_165085503.1\|119974_120619_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NZ_CP049316.1\|WP_165085511.1\|123303_123978_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NZ_CP049316.1\|WP_165085521.1\|134236_135019_+\|DUF1295-domain-containing-protein	unknown	unknown	gnl\|CDD\|284403
NZ_CP049316.1\|WP_165085523.1\|135070_136156_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139
NZ_CP049316.1\|WP_165085514.1\|130541_131606_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|236974
NZ_CP049316.1\|WP_165085498.1\|118630_118921_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP049316.1\|WP_165085490.1\|114428_114956_+\|carbon-monoxide-dehydrogenase-subunit-G	unknown	unknown	gnl\|CDD\|176853
NZ_CP049316.1\|WP_165085512.1\|124064_126281_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NZ_CP049316.1\|WP_165092999.1\|129585_130266_-\|peptidase	unknown	unknown	gnl\|CDD\|225832
NZ_CP049316.1\|WP_165085513.1\|128366_129488_+\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|377164
NZ_CP049316.1\|WP_165085501.1\|118931_119972_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP049316.1\|WP_165085528.1\|137736_138432_-\|dienelactone-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223489
NZ_CP049316.1\|WP_165085518.1\|133736_133922_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049316.1\|WP_165085492.1\|114928_115948_+\|XdhC-family-protein	unknown	unknown	gnl\|CDD\|224886
NZ_CP049316.1\|WP_165085495.1\|116005_116755_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224137
NZ_CP049316.1\|WP_165085526.1\|136185_137658_-\|amidase	unknown	unknown	gnl\|CDD\|223232
NZ_CP049316.1\|WP_165085515.1\|131690_131903_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP049316.1\|WP_165085506.1\|120623_121496_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.87021e-153
NZ_CP049316.1\|WP_165085516.1\|132235_133492_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.03877e-71
NZ_CP049316.1\|WP_165085509.1\|121492_123307_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NZ_CP049316.1\|WP_165085503.1\|119974_120619_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	2.37585e-41
NZ_CP049316.1\|WP_165085511.1\|123303_123978_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	8.12568e-111
NZ_CP049316.1\|WP_165085521.1\|134236_135019_+\|DUF1295-domain-containing-protein	gnl\|CDD\|284403	pfam06966, DUF1295, Protein of unknown function (DUF1295). This family contains a number of bacterial and eukaryotic proteins of unknown function that are approximately 300 residues long.	1.77007e-63
NZ_CP049316.1\|WP_165085523.1\|135070_136156_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	2.07332e-61
NZ_CP049316.1\|WP_165085514.1\|130541_131606_-\|serine/threonine-protein-kinase	gnl\|CDD\|236974	PRK11768, PRK11768, serine/threonine protein kinase.	0
NZ_CP049316.1\|WP_165085498.1\|118630_118921_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.29359e-31
NZ_CP049316.1\|WP_165085490.1\|114428_114956_+\|carbon-monoxide-dehydrogenase-subunit-G	gnl\|CDD\|176853	cd05018, CoxG, Carbon monoxide dehydrogenase subunit G (CoxG). CoxG has been shown, in Oligotropha carboxidovorans, to anchor the carbon monoxide (CO) dehydrogenase to the cytoplasmic membrane. The gene encoding CoxG is part of the Cox cluster (coxBCMSLDEFGHIK) located on a low-copy-number, circular, megaplasmid pHCG3. This cluster includes genes encoding subunits of CO dehydrogenase and several accessory components involved in the utilization of CO. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	2.1414e-59
NZ_CP049316.1\|WP_165085512.1\|124064_126281_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.00056e-54
NZ_CP049316.1\|WP_165092999.1\|129585_130266_-\|peptidase	gnl\|CDD\|225832	COG3295, COG3295, Uncharacterized protein conserved in bacteria [Function unknown].	1.87679e-33
NZ_CP049316.1\|WP_165085513.1\|128366_129488_+\|PepSY-domain-containing-protein	gnl\|CDD\|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.99797e-55
NZ_CP049316.1\|WP_165085501.1\|118931_119972_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP049316.1\|WP_165085528.1\|137736_138432_-\|dienelactone-hydrolase-family-protein	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	2.64416e-61
NZ_CP049316.1\|WP_165085492.1\|114928_115948_+\|XdhC-family-protein	gnl\|CDD\|224886	COG1975, XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones].	1.27596e-77
NZ_CP049316.1\|WP_165085495.1\|116005_116755_-\|hypothetical-protein	gnl\|CDD\|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	3.42346e-05
NZ_CP049316.1\|WP_165085526.1\|136185_137658_-\|amidase	gnl\|CDD\|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	1.58165e-122

>NZ_CP049316.1|WP_165085512.1|124064_126281_-|CRISPR-associated-helicase-Cas3'
MTRVFHAHSTPNPDESDWQTLPDHLNAVGELAGQSARHFGAARLAETAGKLHDLGKYTDAYQQRIRGGPRVDHATWGAKIACKQYGALGRLMAYGIAGHHAGLANGRDPGSRTALDGRLAADLPDLFNDYLKDLVLPTTAKEMEPTRWKQNAERPQFQLSMLTRMIFSCVVDGDYLDTDRFYAKTEDRPLDRDTPKPTLIELRAKLGAYLNAFAVVNPIDTTRALVLSHARSHAGDRIGMFSLTVPTGGGKTLTSLAFALDHAIAHGLDRVIFVIPFTSIVEQNAAVFKQAFGDLGDAAVLEHHSAFVPTPGENAEAAAKLRVVMDNWDAPVIVTTSVQFFESLYASKPSQCRKLHNIAGSVVILDEAQALPLKLLRPCVAVLDELALNYRTSVVLCTATQPALNAPEFPGGFKNVVELAPDPEALFETLARVTVKSAGTLDDPALTQRMRDHEQVLCIVNNRRHAQALYTSIAGENGARHLSTLMYPKHRTRVLNEVREMLKDKETCRLVSTSLIEAGVDIDFPYVMRAEAGLDSIAQAAGRCNRSGKRSRTESLVEVFAPENTDWAPPKALETLADKGREVMRTSAADPLSIAAINAYFNAVYWQTGPEKLDEHNLLGTIEDDGLKGFKFELIDQQFQMIDSVQMPAIIPGDAECKALLEELKDTKNCGCIARKLQPYLIQIPHEVYNALAASRAIQPVAEHKYGTQFMQLIMMNLYTERFGLKLDGSIDPDSLIH
>NZ_CP049316.1|WP_165085511.1|123303_123978_-|type-I-C-CRISPR-associated-protein-Cas5
MAYGIRLLVKGERALFTRPEMKVERVSYDVITPSAARGIVEAIHWKPAIRWVIDRIQVLNEIRFDTIRRNEVASKIPGSSARSAMKKGTLEGLVNYVDEDRQQRAASILKDVAYVIEAHFVLTDKAEDGDSIGKHLDIFNRRARKGQCFQMPCFGVREFPADFTLLEDDERAHEPHESLIAQKDLGWMLHDIDFKNAMTPHFFRASIQNGWIDIPPLSFAERAA
>NZ_CP049316.1|WP_165085509.1|121492_123307_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MIFKSLVEYYERLALQGKVPPFGLTQEKIGYAFLLDHDGKLQDVINLSDPDDKKSKWKMMPVTASFKRPGSAPPSFFLWDKTAFVLGVEQKVGSDVPTLNLKSHASFKALHLDRLADSTDAGLVALRKFIEAWIPEQWAQCEQIVKHVPAIFSANIVFRLDGELSYIHERAAAQELIKRYSTTDEAAIGLCLVSGETRPIARLHPAIKGVWGAQSAGASIVSFNLDAFDSYGKERGANAPVSVHAAFAYTTVLNYLLLRDPHHQQCVQIGDASVVFWAEAKDQQKQEAAESLFFSALQPPPTDSAEAAKLKHALEAVSAGRGLNDLDANLDPKSKMFVLGLSPNASRLSVRYWFTESLGKFAKRLAQHYNDLTIEPTPWKTLPVAWRLLASIAAQEKTENVPPQLAGAVMRAVFSGGRYPRTLLSAAIMRMRADGDISGLRVALCKAVLTRDQRLDNNDNQQEVPVSLDRSNTTPGYLLGRLFSALESIQEAALHSVSASIKDRYYGSASAMPAGVFPALMRGAQNHLSKAMKDPKGKGLAISLEKEVQQIVDGLGCEFPKTLRLEDQGRFAIGYYHQRNERFRSKASKDEAAEITDDTLETTV
>NZ_CP049316.1|WP_165085506.1|120623_121496_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTILANRYEFVYLFDVTNGNPNGDPDAGNLPRLDPETNLGLVTDVCLKRKIRNYVTLEKDNKAGHAIYMQEKAVLNLQHKLGYAALNLVPVDKKLPKDPKDAEALTKWMCTNFFDVRAFGAVMSTGVNCGQVRGPIQLAFAKSIEPVTPMEISITRMSVTSEKDAENSDRTMGRKHILPYGLYRAHGFISAKLAERTGFTEDDLELVWRSLTNMFEHDRSAARGEMAARKLIVFKHESALGNAPAHTLFDAVKVERVKEGSDLPARFFSDYTVSIDKAKIASGVEVIDRI
>NZ_CP049316.1|WP_165085503.1|119974_120619_-|CRISPR-associated-protein-Cas4
MTNSSQPDETIALSALQHYLFCARQCALIHVEQIWSENIFTAEGRVLHEQADKPLAESRRGVRTVTAMPLSNAELGIAGVADVVEFHRLEAERAERAYPVEYKRGKPKAHRADEVQLCAQALCLESMLKQSIGEGALFYGKTRRRRVVAIDAELRALTIGTIGAVRALVRDGRTPPARYEPHRCDSCSLIDDCRPQMLGRHLSAKAWFEAQLED
>NZ_CP049316.1|WP_165085501.1|118931_119972_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MRRQLNTLYVTTEGAWLKKDGANVVMEVEGDERARLPIHMLASVVCFGRVMISPPLLGFCVESGVSVAYLSMHGRFLARVEGPVSGNVLLRREQYRVSDDLVRAAPIVRNVVAGKIHNQRAVLSRALRDYGDGFTDDIRLELERAQKRLSIISRRLLSESDIDILRGLEGEAAQSYFGVFQHLVRVDDPAFKFSGRSRRPPLDAINAVLSFLYTLITHDCRSALETVGLDPAVGFLHRDRPGRPSLALDLIEEMRPVLADRLALSMINRKQLNKKDFRFLDNGACLLTETSRKALLVAYQERKRDEIAHPFLDEKIPLGMVPFVQAQLLARHLRGDLDAYPAFLWK
>NZ_CP049316.1|WP_165085498.1|118630_118921_-|CRISPR-associated-endonuclease-Cas2
MMVLVSYDVATSTEGGTRRLRRVARACKDFGQRVQYSVFEIEVDAAQWTLLKRRLLTVIDPEVDSLRFYFLGNNWERRIEHVGAKEAVDFNAPLIV
>NZ_CP049316.1|WP_165085495.1|116005_116755_-|hypothetical-protein
MSNHHVLICLPTYSEEVHINFAFSLLDLTRALTKSGSSYETLHVASSHIIRARNFFANYFLSRPEFTHLLFLDTDMKFPAEAVIKLLAANKAVAGVAYPFRRIDLNGPISAADTGLTLREWLEKHSEYTIAPIPDANGDVRFVDGFVQARHIGTGVFLAQREAFEATKPFSECYAPPKQYESMLTNGKFYGFFETIEEDGLYQGEDVSFCTRARQAGLTIWGLIDQTVVHYGASEVSGQYLQAMRRKEK
>NZ_CP049316.1|WP_165085492.1|114928_115948_+|XdhC-family-protein
MDSVDLEVLRNSARWLERGHRVLLVTVVKTWGSSPRPEGAMLAVRDDGAVMGSVSGGCIEDDLIERVRQRGIEQTKPESVKYGISAEEAHRFGLPCGGTIQLVLEPLSMASGIAELCDAVLAGRLVTRTLDMANGAVKLEPAQATDGVTFDETTLSTIHGPRYRMLVIGAGQLSRYLCSIAVGLDYHVTVCDPREEYTDEWDVPGTKIVRTMPDDTVMDMKLDERCAVIALTHDPKLDDLALMEALKTPAFYVGALGSRKNNAARRERLKEFDLSDAELSRLHGPVGIYIGSRTPPEIAVSILAEVTAAKNGVSLPTILQVEGAKAARELEGTGEVCGI
>NZ_CP049316.1|WP_165085490.1|114428_114956_+|carbon-monoxide-dehydrogenase-subunit-G
MELTETHNLPVPQDIAWQALNDTEILRACIPGCESIEADGENAYAVAMTASVGPVKAKFKGRMNLVDIDAPHTYTIVFEGQGGTAGFGKGQAKVNLEPGDNADSTTLSYTANAQVGGKLAQIGSRLVDGAARKIAGEFFKRFSAQLTQGDEPGSAGDEGEEKKGKRSWTAWISKS
>NZ_CP049316.1|WP_165085513.1|128366_129488_+|PepSY-domain-containing-protein
MLSSRSLRIWSFVHRWTSIVCTAFMLLLCLTGLPLVFGHELDVLLGDAIEAPELPAHQSNARASYDAILNSALAKNPGHVPQYMIWEPDESMLPIVVTAPRPDTPPDDTQSTTIDARTARALGAPPGKGSLKFILLKLHVDMFAGLPGKLFLGAMGVSFVVAIVSGVVVYLPFWKKVGLGRVRIKKSRRIAWLDGHNALGMLTLVWALLVGATGSINTLADLLLDAWRNDQLAQMLAPYQGKPPVKATASVDEAIKIARDKTPSMIPSFVAFPGTRFSSPHHYTVFMRGDGILTTRMLRPVLIDAETGKLTDSRELPWYLTLLLGSQPLHFGDFGGMPLKIFWAAFDVLTIVVLGSGLYIWLSRGNKNKRKPA
>NZ_CP049316.1|WP_165092999.1|129585_130266_-|peptidase
MPYAPRGGRLIDDAEQFTRKQRSRRATFIKWLRKVHGWVGLWGAVLGLLFGTTGFLLNHRAGPLKISSGEPQVSQMQMAVPAHGLKSPMELGKWLKQELKLDGNIGRPKREAAHPVGWGDQKTMQPELWTVAVASPGGSVSAEYWVGNGFVSVKKSENSFLATMTNLHKGVGLSMGWVLLIDTLAGSIILLSLTGVLLWTELNKRKTVGAVIVMASIVAMVCMGLM
>NZ_CP049316.1|WP_165085514.1|130541_131606_-|serine/threonine-protein-kinase
MNSNHSDASRASADSLSFSGDDANLPPPPFADLTPERVLDALDSVLMPLGERTDGGMLALNSYENRVYQVGMEDGPPMVAKFYRPLRWSDDAILEEHAFVSTLYEREIPAVPARVLNGASLHTFDGFRFSIFERRGGRAPDIDRPDTLEWLGRFIGRIHAVGQIKPYVERPALDIQTFGYEPREFLLTHGFVPKDVLEAYETVVKMALEGVERCYERAGDVKSIRLHGDCHPSNVLWTDAGPHFVDFDDSRMAPAIQDLWLLLPGDRPEASRALGDLLAGYEDFCDFEPRELHLVEALRTLRLIHYAAWLARRWNDPAFPAAFPWFNTQRYWEDRILELREQVGAMEEGPLWPV
>NZ_CP049316.1|WP_165085515.1|131690_131903_-|hypothetical-protein
MQIGSIVRSVHIAVPQGARGIVMRILGDMAMVAWYADEPGTSELLNTEPFFLADLIDTGELVRPTNVLMH
>NZ_CP049316.1|WP_165085516.1|132235_133492_+|MFS-transporter
MTSSPAPSRSASSSSLPPDPSPYLERGSRAYWHAAVALLFAGYATFSLLYCVQPLLPEFTKTFGVSPAESALSVSVTTASLAVAIFIAGFVSEGWSRHRLMTLSLTASALLTIIVAFLPSWHALLFVRALEGLALGGVPAVAMAYLAEEVHPDGLGLAMGLYVGGTAIGGMAGRVISGILADFFSWRVAIGGIGVLGLLATLAFRALLPQSRRFVPRAGMGFSHHRMALAGHLKNRGLPFLFLMGFVLMGSFVTLYNYVGYRLIAAPFNLSQTEIGGIFVVYLTGVVASPWSGKMADIFGRGRVLIAALLLMIFGVALTLSSLLAVVIAGIACMTFGFFAGHSVASGWIGVLANGPKGQAAALYLLAYYIGSSVLGSWGGHFWTIAGWPGVSGFVFVLLFIGLGGAEYLRRRERRVNA
>NZ_CP049316.1|WP_165085518.1|133736_133922_+|hypothetical-protein
MNTYFTIADFILIIPMALAGILFLGAVPCATQFRKNTLRVFGALLGVLLAFLLVEGLPALV
>NZ_CP049316.1|WP_165085521.1|134236_135019_+|DUF1295-domain-containing-protein
MPPLTVAVIAFIALIVVFTAVWAWQVKSKNAGMVDPVWAMSLGVVAVLVAVLANGDLHTRVVVGVGGFVWGIRLGLHLWKRNAGHAEDPRYHKFREQWGADANKKMFWFFQMQVVISMLLSLAFFVPAYRATPPGAAWVALAAVIWMISIAGEALADHQLRAFKADPSNHGNVCRAGLWRYSRHPNYFFECVHWVAYIPLAIGVGAWIFAMLLPPVLMAWLLLKVSGVPMVEAESAKKRAGYADYMRTTNALIPWPPRHP
>NZ_CP049316.1|WP_165085523.1|135070_136156_+|class-I-SAM-dependent-methyltransferase
MSQPQEKELPTESWLIDWCERGRLPDSLVRLGMRRLMKQRLRDEGIDDGETRSKRFNRLVDELRASPIAIETQAANTQHYEVPAAFFHGHLGEHLKYSCCLYRTGTETLDQAERAMLEEYAVRAQLTDGQRILDLGCGWGSLSLWLAETYPRSQIVALSNSRGQREFIESEAAERGITNLSVVTGNIVDHQFDPASLGDGFDRVLSIEMFEHMKNYRLLLNKISSWMREDGKLFVHVFAHRTLAYHFEVKDGSDWMSKYFFTGGTMPSEALLLHFQDDLTVDRQWWVSGAHYEKTANHWLANLDAARGELMPLMVQTYGAADAPVWFQRWRMFYMAVAELFGYAGGNEWGVAHYRFSKRSG
>NZ_CP049316.1|WP_165085526.1|136185_137658_-|amidase
MQSEYLDYDAIGLAKLVRSGQVSARELIDAAIARAEAVNPALNAIVLKDYQAARNRASRGGRDGSSTLGEGPLAGVPYLIKDLGAPVAGLRMSMGCRHFQHFTPTEDSLIVARSKQAGLNIFGKTNTPEIGQMPYTEPELFGPARNPWGLDYTPGGSSGGAAAAVAGGVVPLAHAADGGGSIRIPASCCGLFGYKPSNDVQPQPLPAPGDLAVDHAVSRSVRDSALLLDLTSSGQPGAFFRAVGEPCGPLRIGYMEEPQLAESLSADVKAALNDAARLAESLGHRVEPASFGLDFNVLAHAFLVMWSVLAEEIVLHADRISGQKPKRADFEIASWAMARVGQKIGERDLPAALETQRQFKAKMATLMTRYDVLLTPTLAAAPFKIGAKQPSQFERFQMHVLSAFPVEPLLQRMLSVSAKKAFDWAGCTELFNFTGQPAMSVPLYWNARGMPIGVQFAGRMNDDATLFRLAAQLEAARPWFTRRPALIAAR
>NZ_CP049316.1|WP_165085528.1|137736_138432_-|dienelactone-hydrolase-family-protein
MTVTSRWIDIPANGDTFQGYLALPKSGKGPGVVIIQEIFGVNSHIRAVADQYAADGYVALAPDIFWRVQPRVELGYDGADREKAMEIYGKLDVANAVADVTATAAALRALPEVTGKVAAVGYCLGGRLAYLSAAQGAFDIAVAYYGGGIQNELDQADKITVPMQFHYGALDAHIPSDAVDSVKQRFAGKDAQVHVYPGADHGFNCTDRASYNQAASALAHGRTLTFLGEHS

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Crispr_ID: NZ_CP049316_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049316_3

648240-648347

Orphan

Consensus_repeat	Method
ACGTACTCGCCGGATGTTGACCCGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049316_3

>merge|NZ_CP049316|3|648240-648347|CRISPRCasFinder
ACGTACTCGCCGGATGTTGACCCGGCGTGCATAAACCGATCTCGCGTGCGGCGCAGGGAGGCGAGCAGGCCGATCCATCCAACGTATTCGCCGGATGTTGACCCGGCG

>NZ_CP049316|3|3|648240-648347|CRISPRCasFinder
ACGTACTCGCCGGATGTTGACCCGGCG	TGCATAAACCGATCTCGCGTGCGGCGCAGGGAGGCGAGCAGGCCGATCCATCCA
ACGTATTCGCCGGATGTTGACCCGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049316.1\|WP_165086593.1\|645378_646344_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP049316.1\|WP_165086608.1\|651644_653219_-\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237027
NZ_CP049316.1\|WP_165086601.1\|648422_649292_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049316.1\|WP_165093030.1\|653939_654137_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049316.1\|WP_165086606.1\|650694_651480_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380339
NZ_CP049316.1\|WP_165086527.1\|640349_641270_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226910
NZ_CP049316.1\|WP_165086615.1\|656010_656838_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153097
NZ_CP049316.1\|WP_165086613.1\|654466_655246_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP049316.1\|WP_165086596.1\|646512_646935_+\|extradiol-dioxygenase	unknown	unknown	gnl\|CDD\|319909
NZ_CP049316.1\|WP_165086603.1\|649519_650245_-\|3,4-dihydroxy-2-butanone-4-phosphate-synthase	unknown	unknown	gnl\|CDD\|235119
NZ_CP049316.1\|WP_165086577.1\|642694_643792_-\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NZ_CP049316.1\|WP_165086620.1\|657616_659107_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|236722
NZ_CP049316.1\|WP_165086611.1\|653464_653845_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049316.1\|WP_165086618.1\|656925_657432_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049316.1\|WP_165086521.1\|637950_638448_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
NZ_CP049316.1\|WP_165086562.1\|642189_642657_-\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|237573
NZ_CP049316.1\|WP_165086524.1\|638428_640144_-\|apolipoprotein-N-acyltransferase	unknown	unknown	gnl\|CDD\|234721
NZ_CP049316.1\|WP_165086559.1\|641505_642186_-\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|226226
NZ_CP049316.1\|WP_165086599.1\|646945_648124_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP049316.1\|WP_165086580.1\|643834_645196_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl\|CDD\|237673

Protein	Function_ID	Function_description	E-value
NZ_CP049316.1\|WP_165086593.1\|645378_646344_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.84072e-67
NZ_CP049316.1\|WP_165086608.1\|651644_653219_-\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|237027	PRK12266, glpD, glycerol-3-phosphate dehydrogenase; Reviewed.	0
NZ_CP049316.1\|WP_165086606.1\|650694_651480_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	6.26366e-15
NZ_CP049316.1\|WP_165086620.1\|657616_659107_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|236722	PRK10590, PRK10590, ATP-dependent RNA helicase RhlE; Provisional.	0
NZ_CP049316.1\|WP_165086527.1\|640349_641270_-\|CBS-domain-containing-protein	gnl\|CDD\|226910	COG4535, CorC, Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism].	1.82562e-135
NZ_CP049316.1\|WP_165086613.1\|654466_655246_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	3.90585e-95
NZ_CP049316.1\|WP_165086596.1\|646512_646935_+\|extradiol-dioxygenase	gnl\|CDD\|319909	cd07245, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.93999e-18
NZ_CP049316.1\|WP_165086603.1\|649519_650245_-\|3,4-dihydroxy-2-butanone-4-phosphate-synthase	gnl\|CDD\|235119	PRK03353, ribB, 3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional.	8.96798e-124
NZ_CP049316.1\|WP_165086577.1\|642694_643792_-\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	3.50591e-141
NZ_CP049316.1\|WP_165086615.1\|656010_656838_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.63817e-09
NZ_CP049316.1\|WP_165086521.1\|637950_638448_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	1.01267e-12
NZ_CP049316.1\|WP_165086562.1\|642189_642657_-\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|237573	PRK13963, PRK13963, rRNA maturation RNase YbeY.	1.18181e-83
NZ_CP049316.1\|WP_165086524.1\|638428_640144_-\|apolipoprotein-N-acyltransferase	gnl\|CDD\|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	0
NZ_CP049316.1\|WP_165086559.1\|641505_642186_-\|gamma-glutamylcyclotransferase	gnl\|CDD\|226226	COG3703, ChaC, Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism].	7.66063e-58
NZ_CP049316.1\|WP_165086599.1\|646945_648124_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	8.26035e-112
NZ_CP049316.1\|WP_165086580.1\|643834_645196_-\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl\|CDD\|237673	PRK14325, PRK14325, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0

>NZ_CP049316.1|WP_165086599.1|646945_648124_+|MFS-transporter
MPIPLLALAISAFAIGTTEFVIMGLLPDVARDLAVSIPSAGFLVTGYALGVAVGAPLLAVLTAKMPRKLALQLLMGVFIVGNVLCAVAPGYSMLMVARVVTSFAHGSFFGIGAVVAASLVPAEKRASAIALMFTGLTLANVLGVPFGTFIGQEFGWRATFWVVAALGVLSLIGVAALVPNKHDSGPSNLGHELRVLKEPQVWLALAMTVLGFGGVFVVFTYIAPILEQVSGFSPHGVTLVLVLFGVGLTIGNTIGGKLADRALMPSLMGILVALAIIMAIFAKTSHNQMLAAITIFIWGIAAFATVPPLQTRVVEKARHAPNLASTLNIGAFNLGNAGGAWLGGVALSQGHPLDSLPWVAAVVAVIALGVTWYAARLDRGGREARAGAADAV
>NZ_CP049316.1|WP_165086596.1|646512_646935_+|extradiol-dioxygenase
MKLDHVTIVAPDCEPIRHFLVDIAGMKVGPRPPFGIGGYWLYLDDAPAVHLIENGSVLASPPGGRAATRIDHLALRVEGAAEWQALLARLHEHAMPFSEADVPLARERQVFVQLAPGVVVEFVTSNSAFAEPAAFSAFSS
>NZ_CP049316.1|WP_165086593.1|645378_646344_-|LysR-family-transcriptional-regulator
MDRLGDMRLFTEAAALGSLSAAGRKLGLSPAAASARLLKLEKSLTARLFERTTRQLRLTDEGRLYLQHCRIALQAIDDGEAALHAGQNLVRGKVRISATSDFGRNLLCHWLDEFSRVYPDVSFSLTLLDSVSNLLLDDIDLAIRFNRPSEGNLIARRLAPNRRVLCASPDYLARHGEPKTPADLATHVFTVLVTSTATFNQFDFVRGDERFTHTVPLEDAWETNDGALSRAWALSGQGIAHKSIWDIAADVRSGALKILLADWCSNEAAVHAVYHCNRYMAPRVRALLDFLIERFARATAELLGDLAYPPGQQGHEVERTL
>NZ_CP049316.1|WP_165086580.1|643834_645196_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MTKKVYVKTFGCQMNEYDSDKMVDVLGAANGLIQTTTLEDADVILFNTCSVREKAQEKVFSDLGRVRELKEANPNLIIGVGGCVASQEGAAIVSRAPYVDLVFGPQTLHRLPEMIAKRRSSGRAQVDISFPEIEKFDHLPPARVDGPSAFVSIMEGCSKYCSYCVVPYTRGEEVSRPLDDVLTEIAGLADQGVREVTMLGQNVNAYRGPVTQHSTDIVDFATLIEYVAEIPGIERIRYTTSHPKEFTQRLIDTYARVPKLVSHLHLPVQHGSDRILMAMKRGYTVLEYKSVIRKLRAIRPDLSLSTDMIVGFPGETEDDFQKMMKLIDEMSYDTSFSFIYSPRPGTPAANLHDDTPREVKLKRLQHLQATIEANVAKISNSMLGSVQRILVEGPSRKDPSELAGRTENNRVVNFPAPISSHKRLIGQMVDVEINVAYPHSLRGELVLTPATTH
>NZ_CP049316.1|WP_165086577.1|642694_643792_-|PhoH-family-protein
MKTAQQHMEFTAPRDDNARLANLCGPLDENLRQIEQALDVTLTRRGHKITIRGRGAKVALAALENFYNRAKDTLSVDDIQLALVEARNAARRGLNVNKPSNNLNSDPVDPRFRGDPDHPFDEPSATIDLGEEEDPGPKLYTRRADLRGRTPMQREYLKQIIAHDVTFGIGPAGTGKTYLAVACAVDSLERDQVKRIVLTRPAVEAGERLGFLPGDLAQKVDPYLRPLYDALYDLLGFDKTAKMFERQMIEIAPLAYMRGRTLNHAFIILDEAQNTTPEQMKMFLTRIGFGSKAVVTGDTTQVDLPRGHRSGLIEAQHILADVRGIAMTKFTSVDVVRHPLVARIVEAYDAQSQRDTVAAAASAGK
>NZ_CP049316.1|WP_165086562.1|642189_642657_-|rRNA-maturation-RNase-YbeY
MPKLALSLQFPAAKTFPEHKALLPRATVASWIKASLFADAELTVRFVDTEEGRTLNRSYRQKDYATNVLTFAYAESEDDPVTGDLVLCCPVVEREAREQNKPLAAHYAHLIVHGTLHAQGYDHEDSAEAEEMESIETGIMQKLGFTDPYLPLPPN
>NZ_CP049316.1|WP_165086559.1|641505_642186_-|gamma-glutamylcyclotransferase
MTPDPSPLSELPAQTPDDYPPVFAESRLLTDEELAASREKALAHWDRKTDLWLFGYGSLIWNPGLPAVETVRSKVHGYHRGLYLWSRVNRGTPEQPGLVLALDRGGSCSGMAFRLAAEGAEPHLDVLWRREMAMNSYRVAWLPCTLVDGRRVEALAFVMRREASTYTGKLADQMVRHVLGCATGRYGTTLDYVSRTVEALRECGMPDRQLEALLQRCCRDANSSQE
>NZ_CP049316.1|WP_165086527.1|640349_641270_-|CBS-domain-containing-protein
MNDAYPSRRHTDKPPEKRTLLERLTDFISHEPESRDELLEVLQDAHERNLLDADSLSMIEGVFQVSELCARDIMIPRAQMDAINIAETPEQFIPFMLEKAHSRYPVFESNRDNVIGVLLAKDLLRYYHEEEFDVRGMLRPAVFIPESKRLNVLLHDFRVNRNHIAIVVDEYGGVAGLITIEDVLEQIVGDIEDEYDFDEEAGNIIATPDGAHRVRALTGIEQFNEQFGTHYSDDEVDTIGGLVTHRFGRVPHRGEKVRIDDFAFEILRGDARQIHVLRVRRAPHTNVLDGNSRNHHRDSVHDDERD
>NZ_CP049316.1|WP_165086524.1|638428_640144_-|apolipoprotein-N-acyltransferase
MADSSSPVTSRNGSQPMSSKKLTGAAQSLPFWHYLVAAVLGAANTLSFAPTPHGGWVELVIFTLFFAWLTRTSGWKGAALTGWAFGFGNFVTGVWWLYVSMHDYGGMAAPLAAAAVALFSMYLAIYPALAGVVWSLCAGRARYEDNGSSAAVPVDEPRFMPTWHGAFAFASAWALGEWLRGLVFTGFPWLASGYAQVDGPLSGFGPVAGVYGVGWVLGLVAALLVQGFYGFRRNSAAQTSQAARLAPFIVAVVLLASGMLLSLVEWTIPANAPLTVRLLQGDVKQEMKFEQEGVDQSLALYKKLITEKPADLIVTPETALPILAVEVPPDLALALRKFSDTTNSSILFGAIGVTASEGRVTGYTNSLFGITPNQRDVYRYDKHHLVPFGEFVPTGFHWFVALMGIPLGDLGRGPPVQKSFFVHNQPIAVDICYEDIFGEEIARTIREQEAPAGILVNSTNLAWFGDTIALDQHLQMARMRSIETGRPMLRSTNTGTTAVIAANGTVVARLPVYTVGSLEATVQGTSGRTPYVTSGNLTVIVVSLLLLAFAFAFAPGRNGRNKPDNNGSKKS
>NZ_CP049316.1|WP_165086521.1|637950_638448_-|GNAT-family-N-acetyltransferase
MVPKNPELALFAIRKAVRADADAAWEIRRAAVMTECVNAYPLDQLEQWTGGTASRAFADAVEERFLVATVDEHVAGTGMIDIETGKIDAIFVHPAYMKHGIGAAMMRHLETLARSQGLRELKLDSTLNAAPFYRALGFDGDEIAQYHSPRGLTMDCVPMTKRLHG
>NZ_CP049316.1|WP_165086601.1|648422_649292_+|hypothetical-protein
MEDITLRQCLKGAWRDAASAVRHMPIVFLVAFVAVLATATAGYKAQFPGMEASGASLTAMTSTSAGHAAGFAQGLISLGVTFVQTLILAVLAVFVVRFAMKLNAEPAGASATSAPVLPATRLWDAGIRRYFLLCIALIAGYVGAMLAVVIVWIGLRLAGLSSGTSMAATATLAILVVCGVSYVSARLSLLFPHTAAGGRIQWRAAWEDTRGHFWFITTAAVLAILPIVGIATVLTVIAEMLATTGSIGGMTMGLMVVQSVGTVLYTATGATCSVWLYRKLAAILKAEAK
>NZ_CP049316.1|WP_165086603.1|649519_650245_-|3,4-dihydroxy-2-butanone-4-phosphate-synthase
MSDSVFTSTSQATAFADLAQLRAGDAPVAIPHRIAAALQALREGRAVALLDDDDRENEADLIYAAEKLDVEGMALMIRECSGIVCLCLPDETVRALHLPPMVADNGSKYGTAFTVSIEAREGVTTGVSAVDRLTTIRAAIADNAKAGDIVSPGHVFPLRAQPGGVLTRRGHTEGTVDLTILAGLKPAGVLCELMNPDGTMARGAQIDAFVKERNIPVLTIAELADFRMALAAARELAEETV
>NZ_CP049316.1|WP_165086606.1|650694_651480_-|helix-turn-helix-domain-containing-protein
MVAPAYSSLELVRESFDAHAPAELAEATQAGSANIAANIPANIPTNTHHAHNTDAQEANDALEYLVGVNLARLRAERQLSLDALARASGVSRAMLAQIESGRSVPSIKVLHKIASALKVSVAAFLRRHATNGIEYLPAEQATRLVTSNGRFSARPLFPLNAPGSAEFHELRIAPLHAESGSPRPPGTTINLVVSDGTLEIRVHDRAQLLATGDAIVFDADQPYTLRNPGNTEARAYQVTVNAETPPRWHVPADLRRIDDAS
>NZ_CP049316.1|WP_165086608.1|651644_653219_-|glycerol-3-phosphate-dehydrogenase
MQGNLYDVLVVGGGVNGTGIARDAAGRGLTVILCEKDDLASHTSSSSTKLIHGGLRYLEYGEYRLVRKALQEREVLLRAAPHIMWPLRFVMPHMPNLRPAWMIRAGLFLYDHLARRELLPGSRGIDMRRHPAGAPLIDSIKRGFVYSDGWVDDARLVALNAVDAQEHGAVIKTRTRLVSARRFEGVWHATLGDNHGATFDIRARSIANAAGPWVSDLLKDSLNSNTHTRHTVRLVKGSHIVTRRLFEHDHAYIFQNPDKRIIFAIPYEHDYTLIGTTDLEYHGDASKVAISPEETAYLCDSINRYFKKHISPADVCWTYAGVRGLLEDENAENASAVTRDYLLELDTPANEAPLLSVFGGKITTFRKLAEEAVDKLGEALQSPARTKTWTEGAPLPGGDIANANFALFLSSFKQRNRWLPGELAHRYARAYGTRAQKLLGDASSLADLGEALAPGLYEAELRYMRDNEWATCADDVLWRRSKLGLHLEPGSLDDVIRRIDGWFASSKPEAEPRATSSMPIRTVV
>NZ_CP049316.1|WP_165086611.1|653464_653845_+|hypothetical-protein
MRKMWVAGALGALMLGGCISTPDVSGSRGAPSLAALQSMCGGSAVDYGTDAQGVYSAFLDAYVAQKRGKLPKEQFCAFQAGIAGQYAAFSASRTAAAQSAWASFFADQRAQALSWRATVDPTLRAG
>NZ_CP049316.1|WP_165093030.1|653939_654137_-|hypothetical-protein
MLSPHEFATLLLLQDAPNQMEMVRDELDALLERQLVQLENLASGRQLWSLTASGDSTIKAIKRYS
>NZ_CP049316.1|WP_165086613.1|654466_655246_-|DeoR/GlpR-transcriptional-regulator
MTRDPRITLNARQQELLDWVQRDGFVTVEDLATHFDVTPQTIRRDVNWLSDMNLLRRYHGGASLPTSSENVSYTARQRMFHDEKRRIAALVASHIPDQASLFINLGTTTEEVARALNRHRGLHVITNNLNVASMMSGYPECEVLITGGIVRPWDKGIVGELAIDFIRQFKVDFAIIGASSIETDGTLRDFDTREVRVAEAIIKHARTVFLAADHSKFGRPALVRLGHLSQIDALFTDAPAPPEMAQTLAEANTQVFVAE
>NZ_CP049316.1|WP_165086615.1|656010_656838_+|ferritin-like-domain-containing-protein
MHTDSTHVMPWRIEDIDLSRIDRRKAASNEHLLLLLCAASFIESGTDLYTSNLSTYFNDDPEVSDWLNNEWEPEEMQHGRALKTYIHHVWPEFDWDTAFKNFFAEYSLTCSVEDFEKTRALEMVARCVVETGTATLYRAINDCSDEPVLKQLTDNIRTDEVRHYKHFFRFFKKYNKIEGNGRFAVLGALLRRVMEIKNEDSEIALRHVFAIRYPERAHDTAHNRELAARVNALVRRNLSADMCVKMLLKPLDLPARIQPSVHYPLAKITQHVFFR
>NZ_CP049316.1|WP_165086618.1|656925_657432_+|hypothetical-protein
MTDSNAFGIEHGTFDEWPAGLRTLFDGTSIETKMGFTASLLAADEGRVRTSLLSVGELFTPDPGTLCFSLWPQSRAARLVSKTGNATLTFVFDEAFFQVQLEARIVPLEGAPATCFIATIESGEWQTVPYARLVHGIGFEFAPGQGDAVLARWREQIDALKRAASAAA
>NZ_CP049316.1|WP_165086620.1|657616_659107_-|DEAD/DEAH-box-helicase
MSFDSLGLSEPLLRAVNELGYTIPTPIQLQAIPAVLNGGDLLAGAQTGTGKTAGFTLPILQRLSEAPAALAGAKRPVRALILTPTRELAAQVEESVRGYGKYLKLKSTVMFGGVGINPQIDALRRGVDIVVATPGRLLDHMQQRTIDLSKLEILVLDEADRMLDMGFIHDIKRVLAKLPPKRQNLLFSATFSEEIKTLADSLLDRPALIEVARRNSTVEAIAQKIHPVDRDKKRELLTHLIRQNNWFQVLVFTRTKHGANRLAEQLTKDGISALAIHGNKSQSARTRALAEFKDNTLQVLVATDIAARGIDIDQLPHVVNFDLPNVPEDYVHRIGRTGRAGATGEALSLVCVDEHQLLKDIERLIKRPIPQEVIAGFEPDLTQKPEPILRRGQGGGGARQGQGAPRQGAPKQSNGGGRPSAKPASGNGGGNGGNGGGYGSRSPKPVAAKTGGNGAAPRKPEGSRPPGAALLGGKPRSEGGGGAGRRDTPRTGQRGR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP049316_2	2.15\|127400\|35\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127400-127434	35	NZ_CP049316.1	1495069-1495103	0	1.0

1. spacer 2.15|127400|35|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to position: 1495069-1495103, mismatch: 0, identity: 1.0

gttaagcggatgttcgaaccacgccatctgcactt	CRISPR spacer
gttaagcggatgttcgaaccacgccatctgcactt	Protospacer
***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049316_1	1.15\|117904\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117904-117937	34	NZ_CP014308	Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence	522881-522914	6	0.824
NZ_CP049316_1	1.15\|117904\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117904-117937	34	NZ_CP014309	Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence	312211-312244	6	0.824
NZ_CP049316_1	1.37\|117905\|34\|NZ_CP049316\|PILER-CR	117905-117938	34	NZ_CP014308	Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence	522881-522914	6	0.824
NZ_CP049316_1	1.37\|117905\|34\|NZ_CP049316\|PILER-CR	117905-117938	34	NZ_CP014309	Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence	312211-312244	6	0.824
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP050953	Rhodococcus sp. DMU1 plasmid unnamed	71679-71711	7	0.788
NZ_CP049316_1	1.2\|117036\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117036-117069	34	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	238186-238219	8	0.765
NZ_CP049316_1	1.24\|117037\|34\|NZ_CP049316\|PILER-CR	117037-117070	34	NZ_CP032697	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence	238186-238219	8	0.765
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	34285-34317	8	0.758
NZ_CP049316_1	1.11\|117638\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117638-117671	34	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	20996-21029	9	0.735
NZ_CP049316_1	1.11\|117638\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117638-117671	34	MT778840	Rhizobium phage P11VFA, complete genome	70356-70389	9	0.735
NZ_CP049316_1	1.14\|117838\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117838-117871	34	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1517710-1517743	9	0.735
NZ_CP049316_1	1.14\|117838\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117838-117871	34	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	221425-221458	9	0.735
NZ_CP049316_1	1.14\|117838\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117838-117871	34	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1499158-1499191	9	0.735
NZ_CP049316_1	1.17\|118037\|33\|NZ_CP049316\|CRISPRCasFinder,CRT	118037-118069	33	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	2149807-2149839	9	0.727
NZ_CP049316_1	1.33\|117639\|34\|NZ_CP049316\|PILER-CR	117639-117672	34	KF614509	Rhizobium phage vB_RleS_L338C, complete genome	20996-21029	9	0.735
NZ_CP049316_1	1.33\|117639\|34\|NZ_CP049316\|PILER-CR	117639-117672	34	MT778840	Rhizobium phage P11VFA, complete genome	70356-70389	9	0.735
NZ_CP049316_1	1.36\|117839\|34\|NZ_CP049316\|PILER-CR	117839-117872	34	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	1517710-1517743	9	0.735
NZ_CP049316_1	1.36\|117839\|34\|NZ_CP049316\|PILER-CR	117839-117872	34	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	221425-221458	9	0.735
NZ_CP049316_1	1.36\|117839\|34\|NZ_CP049316\|PILER-CR	117839-117872	34	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1499158-1499191	9	0.735
NZ_CP049316_1	1.39\|118038\|33\|NZ_CP049316\|PILER-CR	118038-118070	33	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	2149807-2149839	9	0.727
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP016763	Citrobacter freundii strain B38 plasmid pOZ172, complete sequence	2529-2561	9	0.727
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_KX839208	Klebsiella pneumoniae strain KP1814 plasmid pKP1814-2, complete sequence	102322-102354	9	0.727
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	CP052526	Klebsiella pneumoniae strain B16KP0177 plasmid pB16KP0177-2, complete sequence	9494-9526	9	0.727
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP017991	Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence	36389-36421	9	0.727
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP054615	Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence	289697-289729	9	0.727
NZ_CP049316_2	2.11\|127135\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127135-127167	33	KU686197	Synechococcus phage S-CAM3 isolate 0808SB25, complete genome	144136-144168	10	0.697
NZ_CP049316_2	2.11\|127135\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127135-127167	33	KU686199	Synechococcus phage S-CAM3 isolate 1010CC42, complete genome	144471-144503	10	0.697
NZ_CP049316_2	2.11\|127135\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127135-127167	33	KU686198	Synechococcus phage S-CAM3 isolate 0910TB04, complete genome	144456-144488	10	0.697
NZ_CP049316_2	2.11\|127135\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127135-127167	33	KU594606	Cyanophage S-RIM32 isolate RW_108_0702, complete genome	126687-126719	10	0.697
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NC_010335	Caulobacter sp. K31 plasmid pCAUL01, complete sequence	208700-208732	10	0.697
NZ_CP049316_1	1.11\|117638\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117638-117671	34	NZ_LR594664	Variovorax sp. RA8 plasmid 3	194238-194271	11	0.676
NZ_CP049316_1	1.33\|117639\|34\|NZ_CP049316\|PILER-CR	117639-117672	34	NZ_LR594664	Variovorax sp. RA8 plasmid 3	194238-194271	11	0.676
NZ_CP049316_2	2.17\|127534\|33\|NZ_CP049316\|CRISPRCasFinder,CRT,PILER-CR	127534-127566	33	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	947390-947422	11	0.667
NZ_CP049316_1	1.11\|117638\|34\|NZ_CP049316\|CRISPRCasFinder,CRT	117638-117671	34	MK962628	Achromobacter phage vB_AxyP_19-32_Axy09, complete genome	37563-37596	12	0.647
NZ_CP049316_1	1.33\|117639\|34\|NZ_CP049316\|PILER-CR	117639-117672	34	MK962628	Achromobacter phage vB_AxyP_19-32_Axy09, complete genome	37563-37596	12	0.647

1. spacer 1.15|117904|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP014308 (Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.824

cagtggt--acatgcttatctcctttttggcaggcc	CRISPR spacer
--gttgttgacatgcttatttcctttttggcagaca	Protospacer
  ** **  **********.*************.*

2. spacer 1.15|117904|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP014309 (Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.824

cagtggt--acatgcttatctcctttttggcaggcc	CRISPR spacer
--gttgttgacatgcttatttcctttttggcagaca	Protospacer
  ** **  **********.*************.*

3. spacer 1.37|117905|34|NZ_CP049316|PILER-CR matches to NZ_CP014308 (Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.824

cagtggt--acatgcttatctcctttttggcaggcc	CRISPR spacer
--gttgttgacatgcttatttcctttttggcagaca	Protospacer
  ** **  **********.*************.*

4. spacer 1.37|117905|34|NZ_CP049316|PILER-CR matches to NZ_CP014309 (Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.824

cagtggt--acatgcttatctcctttttggcaggcc	CRISPR spacer
--gttgttgacatgcttatttcctttttggcagaca	Protospacer
  ** **  **********.*************.*

5. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050953 (Rhodococcus sp. DMU1 plasmid unnamed) position: , mismatch: 7, identity: 0.788

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
aggtcagctcgacgatgccgtcggcaaccgagc	Protospacer
 *** ************ ******* *  * **

6. spacer 1.2|117036|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 8, identity: 0.765

tgtttgatgcgcttgtgcggtccag-ccggcagta	CRISPR spacer
atcttgatgcgcttgagcggtccagccctgccat-	Protospacer
  .************ ********* ** ** .*

7. spacer 1.24|117037|34|NZ_CP049316|PILER-CR matches to NZ_CP032697 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525a, complete sequence) position: , mismatch: 8, identity: 0.765

tgtttgatgcgcttgtgcggtccag-ccggcagta	CRISPR spacer
atcttgatgcgcttgagcggtccagccctgccat-	Protospacer
  .************ ********* ** ** .*

8. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 8, identity: 0.758

tggtgagc---tcgacgatggcgtcggccaaggtgc	CRISPR spacer
---ccagcctgtcgaggatggcgtcggcgaaggtgg	Protospacer
   . ***   **** ************ ******

9. spacer 1.11|117638|34|NZ_CP049316|CRISPRCasFinder,CRT matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 9, identity: 0.735

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcaggccatcgccgtggcaggcactgccgcagaa	Protospacer
 *  **** ************.*******   .*

10. spacer 1.11|117638|34|NZ_CP049316|CRISPRCasFinder,CRT matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 9, identity: 0.735

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcaggccatcgccgtggcaggcactgccgcagaa	Protospacer
 *  **** ************.*******   .*

11. spacer 1.14|117838|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
acgaaactgtatgtgccgtcgagcgcgtcgtagt	Protospacer
*.*  .*.*****.***********.****** .

12. spacer 1.14|117838|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
tcggccgcgcatgcgccgccgagcgtgtcgtggc	Protospacer
 .* *  **.********.************. *

13. spacer 1.14|117838|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
acgaaactgtatgtgccgtcgagcgcgtcgtagt	Protospacer
*.*  .*.*****.***********.****** .

14. spacer 1.17|118037|33|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.727

gtattgtgcgacgccgacgcccgcttcatattg	CRISPR spacer
gcgcttgccggcgccgaggcccgcttcatattc	Protospacer
*...*   **.****** **************

15. spacer 1.33|117639|34|NZ_CP049316|PILER-CR matches to KF614509 (Rhizobium phage vB_RleS_L338C, complete genome) position: , mismatch: 9, identity: 0.735

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcaggccatcgccgtggcaggcactgccgcagaa	Protospacer
 *  **** ************.*******   .*

16. spacer 1.33|117639|34|NZ_CP049316|PILER-CR matches to MT778840 (Rhizobium phage P11VFA, complete genome) position: , mismatch: 9, identity: 0.735

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcaggccatcgccgtggcaggcactgccgcagaa	Protospacer
 *  **** ************.*******   .*

17. spacer 1.36|117839|34|NZ_CP049316|PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
acgaaactgtatgtgccgtcgagcgcgtcgtagt	Protospacer
*.*  .*.*****.***********.****** .

18. spacer 1.36|117839|34|NZ_CP049316|PILER-CR matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
tcggccgcgcatgcgccgccgagcgtgtcgtggc	Protospacer
 .* *  **.********.************. *

19. spacer 1.36|117839|34|NZ_CP049316|PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.735

atgtcgccgtatgcgccgtcgagcgtgtcgtacc	CRISPR spacer
acgaaactgtatgtgccgtcgagcgcgtcgtagt	Protospacer
*.*  .*.*****.***********.****** .

20. spacer 1.39|118038|33|NZ_CP049316|PILER-CR matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.727

gtattgtgcgacgccgacgcccgcttcatattg	CRISPR spacer
gcgcttgccggcgccgaggcccgcttcatattc	Protospacer
*...*   **.****** **************

21. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016763 (Citrobacter freundii strain B38 plasmid pOZ172, complete sequence) position: , mismatch: 9, identity: 0.727

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
tctggtactggacgatggcgtcggccagggtct	Protospacer
*   * .** *****************.*** .

22. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX839208 (Klebsiella pneumoniae strain KP1814 plasmid pKP1814-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
tctggtactggacgatggcgtcggccagggtct	Protospacer
*   * .** *****************.*** .

23. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to CP052526 (Klebsiella pneumoniae strain B16KP0177 plasmid pB16KP0177-2, complete sequence) position: , mismatch: 9, identity: 0.727

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
tctggtactggacgatggcgtcggccagggtct	Protospacer
*   * .** *****************.*** .

24. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017991 (Enterobacter cloacae complex sp. ECNIH7 plasmid pENT-1ac, complete sequence) position: , mismatch: 9, identity: 0.727

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
tctggtactggacgatggcgtcggccagggtct	Protospacer
*   * .** *****************.*** .

25. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054615 (Azospirillum oryzae strain KACC 14407 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
cgggccgctcgacgagggcgtcggccagggcct	Protospacer
.**   ********* ***********.**. .

26. spacer 2.11|127135|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to KU686197 (Synechococcus phage S-CAM3 isolate 0808SB25, complete genome) position: , mismatch: 10, identity: 0.697

acttgccaagtgtcgtttcggtttcacttgttg	CRISPR spacer
taacgccaagtatcgtttcggattcactggaac	Protospacer
   .*******.********* ****** *

27. spacer 2.11|127135|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to KU686199 (Synechococcus phage S-CAM3 isolate 1010CC42, complete genome) position: , mismatch: 10, identity: 0.697

acttgccaagtgtcgtttcggtttcacttgttg	CRISPR spacer
taacgccaagtatcgtttcggattcactggaac	Protospacer
   .*******.********* ****** *

28. spacer 2.11|127135|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to KU686198 (Synechococcus phage S-CAM3 isolate 0910TB04, complete genome) position: , mismatch: 10, identity: 0.697

acttgccaagtgtcgtttcggtttcacttgttg	CRISPR spacer
taacgccaagtatcgtttcggattcactggaac	Protospacer
   .*******.********* ****** *

29. spacer 2.11|127135|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to KU594606 (Cyanophage S-RIM32 isolate RW_108_0702, complete genome) position: , mismatch: 10, identity: 0.697

acttgccaagtgtcgtttcggtttcacttgttg	CRISPR spacer
taacgccaagtatcgtttcggattcactggcac	Protospacer
   .*******.********* ****** *.

30. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NC_010335 (Caulobacter sp. K31 plasmid pCAUL01, complete sequence) position: , mismatch: 10, identity: 0.697

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
caggatcctcgacgatggcgttgaccaaggtct	Protospacer
..* .  **************.*.******* .

31. spacer 1.11|117638|34|NZ_CP049316|CRISPRCasFinder,CRT matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 11, identity: 0.676

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcggagatgcgctgtggcaggtactgcaggctgc	Protospacer
 *  .   .***.************** *****

32. spacer 1.33|117639|34|NZ_CP049316|PILER-CR matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 11, identity: 0.676

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
tcggagatgcgctgtggcaggtactgcaggctgc	Protospacer
 *  .   .***.************** *****

33. spacer 2.17|127534|33|NZ_CP049316|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 11, identity: 0.667

tggtgagctcgacgatggcgtcggccaaggtgc	CRISPR spacer
ccagcggctcgacgatgccggcggccaaggcct	Protospacer
. .  .*********** ** *********. .

34. spacer 1.11|117638|34|NZ_CP049316|CRISPRCasFinder,CRT matches to MK962628 (Achromobacter phage vB_AxyP_19-32_Axy09, complete genome) position: , mismatch: 12, identity: 0.647

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
ggtcgctaacgccgtggcaggcactgccaaggtc	Protospacer
. ..**.**************.******..

35. spacer 1.33|117639|34|NZ_CP049316|PILER-CR matches to MK962628 (Achromobacter phage vB_AxyP_19-32_Axy09, complete genome) position: , mismatch: 12, identity: 0.647

acctgccaacgccgtggcaggtactgccggctga	CRISPR spacer
ggtcgctaacgccgtggcaggcactgccaaggtc	Protospacer
. ..**.**************.******..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

540165 : 556084

Hokovirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165086397.1\|540165_542121_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	1.5e-146	48.7
WP_165086400.1\|542453_543596_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	3.5e-23	32.4
WP_165086403.1\|543645_545439_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VNU7	Pandoravirus	3.1e-50	34.2
WP_165086407.1\|546077_546893_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	2.0e-36	32.5
WP_165086410.1\|546951_547659_-	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	9.1e-06	26.9
WP_165086413.1\|547673_548201_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_165086415.1\|548284_549925_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	1.6e-24	33.9
WP_165086418.1\|549872_550559_-	HAD family hydrolase	NA	NA	NA	NA
WP_165086420.1\|550634_551366_-	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_165086422.1\|551604_552660_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FK46	Synechococcus_phage	8.9e-74	44.5
WP_165086424.1\|552778_556084_-	DEAD/DEAH box helicase	S5N3Q5	Choristoneura_occidentalis_alphabaculovirus	1.8e-51	33.0

DBSCAN-SWA_2

814143 : 825085

Streptococcus_phage(14.29%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165086954.1\|814143_816249_-	elongation factor G	E4ZFJ7	Streptococcus_phage	2.9e-60	26.8
WP_165093044.1\|816597_817125_-	DUF192 domain-containing protein	A0A222YVT9	Synechococcus_phage	6.7e-14	41.2
WP_165086957.1\|817393_817588_-	hypothetical protein	NA	NA	NA	NA
WP_165086960.1\|817916_818495_-	pseudouridine synthase	NA	NA	NA	NA
WP_165086962.1\|818928_820182_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.8e-12	64.8
WP_165086965.1\|820372_820909_+	hypothetical protein	NA	NA	NA	NA
WP_165086967.1\|820928_821519_+	ImmA/IrrE family metallo-endopeptidase	A0A142KB62	Gordonia_phage	1.1e-07	31.9
WP_031359827.1\|821622_821832_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-22	76.5
WP_031359828.1\|822473_822788_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	3.4e-13	44.6
WP_165086970.1\|822784_825085_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.8e-167	41.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NZ_CP049321

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

110670 : 182314

Burkholderia_phage(17.65%)

integrase,transposase

attL 120484:120500|attR 162993:163009

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_165107729.1\|110670_112170_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_062172269.1\|112166_112985_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.6e-25	32.6
WP_165105819.1\|113119_114628_+\|transposase	transposase family protein	NA	NA	NA	NA
WP_165107732.1\|115468_116800_+	hypothetical protein	NA	NA	NA	NA
WP_165107734.1\|116913_117600_+	hypothetical protein	NA	NA	NA	NA
WP_165107736.1\|119155_119305_-	hypothetical protein	NA	NA	NA	NA
WP_165107901.1\|119361_120048_-	NUDIX hydrolase	NA	NA	NA	NA
120484:120500	attL	NA	NA	NA	NA
WP_165107738.1\|121684_122026_-	hypothetical protein	NA	NA	NA	NA
WP_165107740.1\|122165_122786_+	hypothetical protein	NA	NA	NA	NA
WP_165107742.1\|122782_123379_+	hypothetical protein	NA	NA	NA	NA
WP_165107744.1\|123707_124022_-	hypothetical protein	NA	NA	NA	NA
WP_165107747.1\|124018_124465_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_165107750.1\|124477_124834_-	hypothetical protein	NA	NA	NA	NA
WP_165107753.1\|125254_126442_+	AAA family ATPase	A0A2H4JGZ2	uncultured_Caudovirales_phage	5.1e-09	27.6
WP_165107756.1\|126444_127419_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_165107903.1\|130062_132030_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_165107759.1\|132174_132450_+	HU family DNA-binding protein	B5TA87	Burkholderia_phage	2.6e-17	54.4
WP_165107529.1\|132562_132787_-	hypothetical protein	NA	NA	NA	NA
WP_165107762.1\|132786_133179_-	hypothetical protein	NA	NA	NA	NA
WP_165107906.1\|133663_134428_+	ParA family protein	V5UP47	Mycobacterium_phage	6.6e-18	33.7
WP_165107765.1\|134990_136913_+	KUP/HAK/KT family potassium transporter	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	1.6e-76	33.3
WP_165107769.1\|137765_139016_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.2e-45	42.9
WP_035566418.1\|139839_139935_+	potassium-transporting ATPase subunit F	NA	NA	NA	NA
WP_165107776.1\|139931_141740_+	potassium-transporting ATPase subunit KdpA	NA	NA	NA	NA
WP_165107777.1\|141764_143918_+	potassium-transporting ATPase subunit KdpB	E4ZFI9	Streptococcus_phage	1.2e-27	27.3
WP_165107778.1\|144007_144589_+	potassium-transporting ATPase subunit KdpC	NA	NA	NA	NA
WP_165107779.1\|144588_147381_+	sensor histidine kinase KdpD	W8CYF6	Bacillus_phage	1.0e-15	27.4
WP_165107780.1\|147377_148076_+	response regulator	A0A1J0GWE0	Alteromonas_phage	7.6e-05	29.7
WP_165107781.1\|148911_149328_+	universal stress protein	NA	NA	NA	NA
WP_165107783.1\|150065_150269_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-19	71.6
WP_165107785.1\|152028_152817_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_165107787.1\|153039_153621_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_165107789.1\|153837_154287_+	RidA family protein	NA	NA	NA	NA
WP_165107791.1\|154485_155445_+	hypothetical protein	NA	NA	NA	NA
WP_165107793.1\|156069_157116_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	3.2e-76	45.3
WP_007183032.1\|157112_157952_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	2.4e-77	57.6
WP_165107795.1\|159220_160945_-	DUF2357 domain-containing protein	NA	NA	NA	NA
WP_165107819.1\|160944_162411_-	AAA domain-containing protein	NA	NA	NA	NA
WP_165107822.1\|162407_163808_-	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.2e-30	28.1
162993:163009	attR	NA	NA	NA	NA
WP_165107824.1\|163929_164232_+	hypothetical protein	NA	NA	NA	NA
WP_165107826.1\|164268_164691_-	very short patch repair endonuclease	I6NSG0	Burkholderia_phage	5.2e-17	41.1
WP_165107828.1\|165164_166181_+\|transposase	IS5 family transposase	E5E3P6	Burkholderia_phage	6.9e-116	65.2
WP_165107908.1\|166441_166696_+	hypothetical protein	NA	NA	NA	NA
WP_165107830.1\|167631_168639_+	hypothetical protein	A0A2H4UVR4	Bodo_saltans_virus	9.8e-30	32.4
WP_165107832.1\|168859_169018_-	hypothetical protein	NA	NA	NA	NA
WP_165107910.1\|169807_170266_-	hypothetical protein	NA	NA	NA	NA
WP_165107834.1\|170411_171248_-	NAD-dependent deacetylase	NA	NA	NA	NA
WP_165107835.1\|172567_173377_+	hypothetical protein	NA	NA	NA	NA
WP_165107912.1\|173454_173694_+	hypothetical protein	NA	NA	NA	NA
WP_165107838.1\|173783_174317_-	hypothetical protein	NA	NA	NA	NA
WP_165107840.1\|174572_175013_+	hypothetical protein	NA	NA	NA	NA
WP_165107843.1\|175594_175807_-	hypothetical protein	NA	NA	NA	NA
WP_165107845.1\|175905_176484_-	hypothetical protein	NA	NA	NA	NA
WP_165107847.1\|176797_177169_-	hypothetical protein	NA	NA	NA	NA
WP_165107849.1\|177549_177789_-	hypothetical protein	NA	NA	NA	NA
WP_165107851.1\|178345_180010_-	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_165086648.1\|181090_182314_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	6.5e-52	32.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage