CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049089	Glaesserella parasuis strain vHPS7 chromosome, complete genome	0 crisprs	cas2,DinG,PD-DExK,DEDDh,WYL,cas3	0	0	5	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

440075 : 538924

111

Mannheimia_phage(20.41%)

integrase,transposase,tRNA,terminase,tail,plate

attL 462004:462021|attR 543080:543097

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080691044.1\|440075_441020_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_005712219.1\|441074_441356_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_164692193.1\|441360_442737_+	GTPase HflX	NA	NA	NA	NA
WP_075592452.1\|442793_443468_+	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_005712227.1\|443923_444811_-	N-acetylmannosamine kinase	NA	NA	NA	NA
WP_005712229.1\|444812_445508_-	N-acetylmannosamine-6-phosphate 2-epimerase	NA	NA	NA	NA
WP_015939678.1\|445697_446606_-	pseudouridine-5'-phosphate glycosidase	NA	NA	NA	NA
WP_075605441.1\|446598_447702_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021109894.1\|447880_448324_-	inosine-uridine preferring nucleoside hydrolase	NA	NA	NA	NA
WP_021112711.1\|448606_449866_+	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_021112751.1\|449957_450737_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_005712241.1\|450765_451485_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_021118757.1\|452790_453432_-	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	NA	NA	NA	NA
WP_043896529.1\|453503_453764_-	hypothetical protein	NA	NA	NA	NA
WP_021118756.1\|453747_453954_-	hypothetical protein	NA	NA	NA	NA
WP_021118755.1\|453950_454724_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_075631093.1\|454705_455455_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	A0A2H4UVM0	Bodo_saltans_virus	2.1e-08	25.6
WP_021112938.1\|455703_456159_-\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_035523662.1\|456201_456879_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_021112949.1\|456878_457472_-	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_106379921.1\|457473_458067_-	hypothetical protein	NA	NA	NA	NA
WP_021112928.1\|458721_459816_-	bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_021112912.1\|459883_460339_-\|transposase	IS200/IS605 family transposase	NA	NA	NA	NA
WP_021112921.1\|460420_461473_-	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_075630923.1\|461567_462854_-	histidinol dehydrogenase	NA	NA	NA	NA
462004:462021	attL	NA	NA	NA	NA
WP_021112913.1\|463129_464026_-	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_021112958.1\|464365_465223_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	1.3e-54	37.6
WP_021111166.1\|465808_466483_+	7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter	A0A2I7SAW6	Vibrio_phage	2.3e-59	58.2
WP_021112950.1\|466602_467409_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_035497322.1\|467933_468194_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_035522476.1\|468223_468688_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_075630925.1\|468708_469326_-	VOC family protein	NA	NA	NA	NA
WP_021112937.1\|469362_471090_+\|tRNA	arginine--tRNA ligase	A0A2K9L2F0	Tupanvirus	2.0e-86	34.5
WP_160427827.1\|472128_472807_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_164692064.1\|472940_475118_+	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_005713131.1\|475121_475601_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_160413997.1\|475787_476222_+\|transposase	transposase	NA	NA	NA	NA
WP_021119054.1\|476991_477405_-	DUF2251 domain-containing protein	NA	NA	NA	NA
WP_075630982.1\|477478_478573_-	DUF560 domain-containing protein	NA	NA	NA	NA
WP_021116144.1\|478639_479242_-	hypothetical protein	NA	NA	NA	NA
WP_021116145.1\|479398_479740_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_021116146.1\|479909_481346_-	glycoside hydrolase family 32 protein	NA	NA	NA	NA
WP_035496776.1\|481644_482070_-	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_164692065.1\|483092_486005_+	hypothetical protein	NA	NA	NA	NA
WP_010786782.1\|486081_486462_-	YacL family protein	NA	NA	NA	NA
WP_164692066.1\|486879_487386_-	hypothetical protein	Q9FZU3	Neisseria_meningitidis_phage	2.2e-22	41.2
WP_035497176.1\|487439_487952_-\|tail	tail assembly protein	A0A0M3LPS1	Mannheimia_phage	3.0e-35	50.3
WP_160576958.1\|487981_488743_-\|tail	phage tail protein	A0A0M3LP75	Mannheimia_phage	1.2e-64	48.8
WP_160576955.1\|488813_489092_+	Killer protein	A0A0M3LQB1	Mannheimia_phage	1.8e-18	50.0
WP_021115320.1\|489109_489385_+	HigA family addiction module antidote protein	A0A2L1IV52	Escherichia_phage	6.4e-08	36.2
WP_075630972.1\|489381_490119_-\|tail	phage minor tail protein L	A0A0M3LSQ5	Mannheimia_phage	6.0e-69	54.5
WP_164692067.1\|490128_493782_-	tape measure protein	A0A0M3LS69	Mannheimia_phage	1.2e-133	35.2
WP_021113612.1\|493903_494323_-	HD domain-containing protein	D0UIJ3	Aggregatibacter_phage	7.4e-40	63.2
WP_021111144.1\|494322_494541_-	hypothetical protein	A0A0M3LPI7	Mannheimia_phage	1.9e-26	75.0
WP_164692068.1\|496150_497548_-	DUF4055 domain-containing protein	A0A0M3LQA1	Mannheimia_phage	8.5e-165	64.8
WP_160427672.1\|497557_498058_-	hypothetical protein	A0A0M3LTA2	Mannheimia_phage	5.7e-63	78.0
WP_021115457.1\|498235_498496_+	hypothetical protein	F6MIM3	Haemophilus_phage	2.4e-41	98.8
WP_075630987.1\|498536_499370_-	hypothetical protein	F6MIM2	Haemophilus_phage	6.4e-160	98.2
WP_016057790.1\|499424_499538_-	Com family DNA-binding transcriptional regulator	F6MIM1	Haemophilus_phage	9.2e-14	100.0
WP_075630986.1\|499687_500155_-	enoyl-CoA hydratase	F6MIM0	Haemophilus_phage	3.3e-89	98.1
WP_075630988.1\|500147_500513_-	hypothetical protein	NA	NA	NA	NA
WP_160413804.1\|500814_501372_-	DUF4376 domain-containing protein	F6MIL9	Haemophilus_phage	3.7e-95	91.9
WP_035493216.1\|503735_504302_-\|tail	tail fiber protein	Q6QI98	Burkholderia_phage	4.5e-40	44.0
WP_035523016.1\|504294_505410_-\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	1.4e-53	35.6
WP_021115058.1\|505396_505765_-	lysozyme family protein	NA	NA	NA	NA
WP_075630594.1\|505822_506407_-\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_035523013.1\|506421_507474_-	hypothetical protein	Q6QIA2	Burkholderia_phage	1.1e-58	38.6
WP_012621996.1\|507477_507696_-	membrane protein	Q6QIA3	Burkholderia_phage	9.9e-12	46.3
WP_035523010.1\|507688_508630_-\|tail	phage tail protein	NA	NA	NA	NA
WP_075630595.1\|508629_511308_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	3.8e-28	22.1
WP_012621993.1\|511351_511636_+	hypothetical protein	NA	NA	NA	NA
WP_106380187.1\|511620_511749_-\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_012621991.1\|511750_512038_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_012621990.1\|512117_512378_-	hypothetical protein	NA	NA	NA	NA
WP_075630596.1\|512382_512973_-	hypothetical protein	G9L6G1	Escherichia_phage	1.1e-25	53.9
WP_075630597.1\|513808_515203_-\|tail	phage tail protein	A4JWK5	Burkholderia_virus	1.7e-112	48.2
WP_012621986.1\|515212_515713_-	hypothetical protein	NA	NA	NA	NA
WP_075630598.1\|515712_516150_-	DUF1320 domain-containing protein	NA	NA	NA	NA
WP_012621984.1\|516152_516596_-	hypothetical protein	NA	NA	NA	NA
WP_075630599.1\|516663_517605_-	hypothetical protein	A4JWK0	Burkholderia_virus	4.5e-53	39.1
WP_075630600.1\|517640_518747_-	peptidase	A4JWJ9	Burkholderia_virus	5.3e-69	41.1
WP_035519476.1\|518967_519423_-	phage virion morphogenesis protein	J9SNH3	Pseudomonas_phage	6.0e-19	33.0
WP_021110031.1\|519549_520818_-	phage Mu F like family protein	J9STS2	Pseudomonas_phage	1.3e-58	48.0
WP_078208205.1\|520814_522233_-	DUF935 family protein	A4JWJ5	Burkholderia_virus	2.0e-121	48.6
WP_035498340.1\|522236_523547_-\|terminase	terminase	A0A2P9JZI8	Alteromonadaceae_phage	1.1e-158	66.0
WP_012621977.1\|523533_524106_-	DUF3486 family protein	A0A2I7S9D1	Vibrio_phage	7.0e-33	43.0
WP_012621976.1\|524139_524430_-	hypothetical protein	A0A0C4UR00	Shigella_phage	8.8e-24	59.8
WP_012621975.1\|524433_524763_-	DUF2730 domain-containing protein	M1Q558	Vibrio_phage	6.1e-05	28.0
WP_071610392.1\|524787_525141_-	DUF2681 domain-containing protein	F6MIK1	Haemophilus_phage	2.5e-28	63.2
WP_012621973.1\|525137_525371_-	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	2.1e-23	74.7
WP_075630605.1\|525471_525993_-	glycoside hydrolase family 108 protein	A0A0M3LSH2	Mannheimia_phage	4.5e-71	75.7
WP_075630606.1\|526086_527265_-	hypothetical protein	NA	NA	NA	NA
WP_075630607.1\|527264_528236_-	nucleoid-associated protein	A0A291AUQ0	Sinorhizobium_phage	2.0e-48	35.7
WP_075630608.1\|528283_528643_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_164692069.1\|528757_528994_-	hypothetical protein	NA	NA	NA	NA
WP_075630610.1\|529052_529286_+	DNA-binding protein	NA	NA	NA	NA
WP_012621966.1\|529478_529727_-	hypothetical protein	NA	NA	NA	NA
WP_164692070.1\|529782_529926_+	hypothetical protein	NA	NA	NA	NA
WP_012621964.1\|529922_530225_+	IclR family transcriptional regulator	A0A0S4L7B4	Pseudomonas_phage	3.3e-13	41.8
WP_075630611.1\|530253_531180_+	hypothetical protein	Q6QID9	Burkholderia_phage	8.2e-15	35.6
WP_075630612.1\|531189_533010_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q6QIE0	Burkholderia_phage	1.8e-127	44.3
WP_075630613.1\|533034_534207_+	AAA family ATPase	A4JWN1	Burkholderia_virus	4.7e-108	54.1
WP_075630614.1\|534296_534821_+	host-nuclease inhibitor protein Gam	F6MIJ0	Haemophilus_phage	8.1e-44	51.7
WP_035522948.1\|534817_535033_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_164681663.1\|535025_535184_+	hypothetical protein	NA	NA	NA	NA
WP_075630615.1\|535180_535594_+	hypothetical protein	NA	NA	NA	NA
WP_075630616.1\|535643_536120_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	9.4e-07	28.3
WP_035522939.1\|536101_536464_+	hypothetical protein	NA	NA	NA	NA
WP_075630617.1\|536453_536858_+	regulatory protein GemA	A0A219VHC6	Ochrobactrum_phage	1.4e-06	30.1
WP_035522934.1\|536854_537226_+	transcriptional regulator	Q6QIE8	Burkholderia_phage	9.5e-23	43.9
WP_005712159.1\|538069_538924_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.8e-32	39.5
543080:543097	attR	NA	NA	NA	NA

DBSCAN-SWA_2

542094 : 550489

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021112700.1\|542094_542886_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.4e-10	28.0
WP_010786211.1\|542997_543459_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.6e-43	58.8
WP_021112688.1\|543551_544751_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.3e-99	49.0
WP_075630618.1\|544882_545527_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-42	42.5
WP_075630619.1\|545551_546643_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.9e-51	38.9
WP_021113972.1\|547111_548986_-	PPIC-type PPIASE domain protein	NA	NA	NA	NA
WP_021113971.1\|549169_550489_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.2e-30	35.2

DBSCAN-SWA_3

876562 : 886327

Mollivirus(12.5%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010786632.1\|876562_878077_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.4e-80	39.4
WP_005710639.1\|878207_878792_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	2.2e-29	40.5
WP_159179940.1\|878808_879462_-	uridine kinase	A0A1V0SAA3	Catovirus	3.0e-35	37.5
WP_159179941.1\|879651_880164_-	endopeptidase	A0A0K2SUC1	Clostridium_phage	4.1e-16	40.0
WP_005710633.1\|880215_880512_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.9e-12	38.9
WP_159179942.1\|880528_882916_-\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	1.4e-05	29.9
WP_005714554.1\|883071_884055_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	1.9e-33	37.4
WP_164692091.1\|884364_885045_+	TIGR00153 family protein	NA	NA	NA	NA
WP_010786626.1\|885064_886327_+	inorganic phosphate transporter	E5ES24	Ostreococcus_lucimarinus_virus	1.1e-59	35.5

DBSCAN-SWA_4

1110165 : 1117335

Mannheimia_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010786777.1\|1110165_1110444_+	plasmid maintenance system killer protein	A0A0M3LQB1	Mannheimia_phage	2.6e-17	48.9
WP_035491783.1\|1110460_1110727_+	HigA family addiction module antidote protein	A0A2P1MXE5	Escherichia_phage	6.2e-08	43.4
WP_021112303.1\|1110790_1112011_+	ATP-dependent RNA helicase RhlB	E3T5E1	Cafeteria_roenbergensis_virus	1.7e-39	30.9
WP_035524761.1\|1112020_1113508_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	6.6e-83	45.0
WP_021115958.1\|1113661_1114204_-	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	1.9e-43	56.2
WP_164692111.1\|1114506_1117335_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.9e-305	56.0

DBSCAN-SWA_5

1455844 : 1463670

Thermus_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012621529.1\|1455844_1456816_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-09	28.8
WP_164692154.1\|1457040_1458897_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.4e-106	43.0
WP_044009087.1\|1459071_1459707_-	DUF2625 family protein	NA	NA	NA	NA
WP_005714644.1\|1459812_1460832_-	virulence RhuM family protein	Q9JMN3	Wolbachia_phage	5.2e-95	53.5
WP_010785897.1\|1460886_1461408_-	Fe-S protein assembly co-chaperone HscB	NA	NA	NA	NA
WP_010785898.1\|1461417_1461741_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	8.3e-23	45.8
WP_005714639.1\|1461901_1462285_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	8.5e-51	76.6
WP_021113876.1\|1462449_1463670_-	IscS subfamily cysteine desulfurase	A0A2K9L679	Tupanvirus	4.6e-13	25.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage