CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NZ_CP049189	Enterobacter hormaechei strain Y323 plasmid pIHI2-323, complete sequence	0 crisprs	csa3	3
NZ_CP049188	Enterobacter hormaechei strain Y323 chromosome, complete genome	1 crisprs	DEDDh,cas3,csa3,DinG,WYL	5
NZ_CP049191	Enterobacter hormaechei strain Y323 plasmid pY323-3, complete sequence	0 crisprs	NA	0
NZ_CP049190	Enterobacter hormaechei strain Y323 plasmid pY323-2, complete sequence	0 crisprs	NA	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

23958 : 63400

uncultured_Caudovirales_phage(42.86%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067855.1\|23958_24663_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000193207.1\|32403_33222_+	DUF4942 domain-containing protein	NA	NA	NA	NA
WP_001371952.1\|33218_34424_+	hypothetical protein	NA	NA	NA	NA
WP_000121164.1\|34487_34691_-	hypothetical protein	NA	NA	NA	NA
WP_000078513.1\|34703_36023_-	DUF1173 family protein	NA	NA	NA	NA
WP_000220758.1\|36045_36213_-	hypothetical protein	A0A2D2W2Z9	Escherichia_phage	7.3e-07	50.9
WP_000833380.1\|36273_37701_-	DNA cytosine methyltransferase	E5E3X6	Burkholderia_phage	3.4e-100	52.3
WP_000464825.1\|37915_38431_+	thermonuclease family protein	A0A1X6WF84	Pacmanvirus	2.1e-07	38.6
WP_000975181.1\|38433_39330_+	hypothetical protein	NA	NA	NA	NA
WP_001005009.1\|39377_39692_+	hypothetical protein	NA	NA	NA	NA
WP_000637193.1\|39765_40023_+	hypothetical protein	NA	NA	NA	NA
WP_001371914.1\|41009_41207_+	hypothetical protein	NA	NA	NA	NA
WP_000864986.1\|41347_41623_+	hypothetical protein	NA	NA	NA	NA
WP_000927306.1\|42114_43593_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	7.3e-199	74.4
WP_001066652.1\|43611_44439_+	universal stress protein	A0A2H4J154	uncultured_Caudovirales_phage	4.9e-43	37.2
WP_000065802.1\|44498_44924_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	1.6e-50	70.7
WP_000922628.1\|44936_46226_-	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	9.9e-168	71.4
WP_000941305.1\|46271_46592_-	transcriptional regulator	A0A2H4J145	uncultured_Caudovirales_phage	1.7e-20	53.7
WP_000130816.1\|46678_47383_+	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	8.8e-86	72.9
WP_000125668.1\|47415_48819_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_022652343.1\|49038_50007_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	3.7e-183	98.1
WP_012695467.1\|50028_50613_-	MFS transporter	NA	NA	NA	NA
WP_021243026.1\|50690_51848_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_012695469.1\|52041_52935_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012695470.1\|53071_53887_-	aminoglycoside O-phosphotransferase APH(3')-Ia	A0A193DTG4	Autographa_californica_nuclear_polyhedrosis_virus	7.4e-161	98.2
WP_072034961.1\|55015_55417_-\|transposase	IS5/IS1182 family transposase	A0A1B0VFY5	Salmonella_phage	2.9e-65	98.4
WP_001567369.1\|55491_56124_+	hypothetical protein	NA	NA	NA	NA
WP_001567368.1\|56152_57556_-\|transposase	ISNCY-like element ISKpn21 family transposase	NA	NA	NA	NA
WP_004143398.1\|57745_58141_-	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_077253535.1\|58189_59536_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_000785965.1\|59756_60074_+	hypothetical protein	NA	NA	NA	NA
WP_001100610.1\|60096_60402_+	hypothetical protein	NA	NA	NA	NA
WP_000285959.1\|60446_61118_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_001371904.1\|61575_61983_+	hypothetical protein	NA	NA	NA	NA
WP_000900745.1\|62033_62351_-	hypothetical protein	NA	NA	NA	NA
WP_100185530.1\|62485_63400_-\|transposase	IS5 family transposase	A0A077SK28	Escherichia_phage	3.6e-172	98.4

DBSCAN-SWA_2

106555 : 171431

Escherichia_phage(37.5%)

integrase,protease,transposase

attL 150668:150727|attR 171649:172937

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000219087.1\|106555_107794_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	2.5e-11	23.1
WP_000589001.1\|108215_109556_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_000137794.1\|111430_112036_-	hypothetical protein	NA	NA	NA	NA
WP_000703842.1\|112252_112534_-	hypothetical protein	NA	NA	NA	NA
WP_000802040.1\|112679_112856_-	hypothetical protein	NA	NA	NA	NA
WP_000633161.1\|112909_113221_-	hypothetical protein	NA	NA	NA	NA
WP_000814953.1\|113443_113644_-	hypothetical protein	NA	NA	NA	NA
WP_000551490.1\|113683_113908_-	hypothetical protein	NA	NA	NA	NA
WP_000781547.1\|113962_114166_-	hypothetical protein	NA	NA	NA	NA
WP_001371932.1\|114718_115210_-	DUF3085 domain-containing protein	NA	NA	NA	NA
WP_001165367.1\|115214_115526_-	DUF957 domain-containing protein	NA	NA	NA	NA
WP_000071366.1\|116042_116363_-	hypothetical protein	NA	NA	NA	NA
WP_001371935.1\|116541_116772_-	hypothetical protein	NA	NA	NA	NA
WP_000252081.1\|116943_117837_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|118146_118851_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_000842134.1\|119340_120450_-	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	2.8e-33	30.2
WP_001039466.1\|120544_121729_-	tetracycline efflux MFS transporter Tet(D)	NA	NA	NA	NA
WP_000113282.1\|121824_122481_+	tetracycline resistance transcriptional repressor TetR(D)	NA	NA	NA	NA
WP_001067855.1\|122492_123197_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001011939.1\|123340_123982_-	type A-2 chloramphenicol O-acetyltransferase CatII	G3CFL0	Escherichia_phage	7.3e-55	45.9
WP_001239317.1\|124131_124632_-	hypothetical protein	NA	NA	NA	NA
WP_001067855.1\|124711_125416_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_001044210.1\|125421_125562_+	hypothetical protein	NA	NA	NA	NA
WP_000743213.1\|126781_127006_+	hypothetical protein	NA	NA	NA	NA
WP_165698993.1\|127127_127286_+	DUF4102 domain-containing protein	G9L697	Escherichia_phage	2.6e-06	82.8
WP_042863651.1\|128566_131533_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	72.8
WP_001067855.1\|131653_132358_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_149847241.1\|132348_135291_+\|transposase	Tn3-like element Tn3 family transposase	Q1MVP5	Enterobacteria_phage	0.0e+00	100.0
WP_000175475.1\|135516_135753_+	hypothetical protein	NA	NA	NA	NA
WP_001100635.1\|135778_136072_+	hypothetical protein	NA	NA	NA	NA
WP_001287391.1\|136249_136654_+	H-NS histone family protein	NA	NA	NA	NA
WP_000784387.1\|137260_138118_-	HNH endonuclease	G0X580	Salmonella_phage	3.9e-11	34.2
WP_001224686.1\|138133_138442_-	hypothetical protein	NA	NA	NA	NA
WP_000278471.1\|138990_139416_-	hypothetical protein	NA	NA	NA	NA
WP_001641519.1\|139668_140484_-	HNH endonuclease	G0X580	Salmonella_phage	2.5e-15	37.2
WP_000985909.1\|140496_140907_-	hypothetical protein	NA	NA	NA	NA
WP_000134171.1\|141007_141214_-	hypothetical protein	NA	NA	NA	NA
WP_000088044.1\|141274_142600_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_012477377.1\|142604_142898_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000083579.1\|143298_144687_-	hypothetical protein	NA	NA	NA	NA
WP_000340139.1\|144691_145189_-	membrane protein	NA	NA	NA	NA
WP_000462754.1\|145391_146048_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_000341066.1\|146706_147099_-	hypothetical protein	NA	NA	NA	NA
WP_000211823.1\|148019_149006_+	hypothetical protein	NA	NA	NA	NA
150668:150727	attL	NA	NA	NA	NA
WP_000427623.1\|150944_151949_-\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
WP_010791757.1\|152098_153781_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	M4T586	Rhodobacter_phage	3.7e-05	24.7
WP_000393453.1\|153783_154692_+	AAA family ATPase	NA	NA	NA	NA
WP_011405615.1\|154688_155906_+	TniQ family protein	NA	NA	NA	NA
WP_010981357.1\|155966_156581_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	5.1e-37	51.0
WP_010981356.1\|156619_156940_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_085013665.1\|156955_157192_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_031942307.1\|157188_157554_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_000761850.1\|157665_158304_-	organomercurial lyase MerB	NA	NA	NA	NA
WP_077269372.1\|158318_158672_-	hypothetical protein	NA	NA	NA	NA
WP_010981353.1\|158601_159036_+	mercury resistance transcriptional regulator MerR	NA	NA	NA	NA
WP_000427614.1\|159114_160119_+\|transposase	IS110-like element IS5075 family transposase	NA	NA	NA	NA
WP_072201471.1\|160692_160905_+	hypothetical protein	NA	NA	NA	NA
WP_021443905.1\|160995_161343_-	mercuric resistance transcriptional repressor protein MerD	NA	NA	NA	NA
WP_058672289.1\|161339_161978_-	organomercurial lyase MerB	NA	NA	NA	NA
WP_011405609.1\|162058_162712_-	phenylmercury resistance protein MerG	NA	NA	NA	NA
WP_011405608.1\|162747_164457_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-34	27.1
WP_011405607.1\|164644_164920_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294663.1\|164933_165284_-	mercuric transport protein MerT	NA	NA	NA	NA
WP_032490487.1\|165355_165790_+	mercury resistance transcriptional regulator MerR	NA	NA	NA	NA
WP_001247892.1\|167316_167607_+	nucleotidyltransferase	NA	NA	NA	NA
WP_001293886.1\|167603_168005_+	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000215515.1\|167994_168351_+	cupin domain-containing protein	NA	NA	NA	NA
WP_003100858.1\|168605_168932_+	hypothetical protein	NA	NA	NA	NA
WP_003100856.1\|168928_169429_+	hypothetical protein	NA	NA	NA	NA
WP_021243030.1\|169425_169797_+	hypothetical protein	NA	NA	NA	NA
WP_003100847.1\|169790_170348_+	recombinase family protein	A0A0C4UR34	Shigella_phage	3.3e-59	63.2
WP_000427623.1\|170426_171431_+\|transposase	IS110-like element IS4321 family transposase	NA	NA	NA	NA
171649:172937	attR	NA	NA	NA	NA

DBSCAN-SWA_3

273008 : 324991

Escherichia_phage(47.06%)

integrase,transposase

attL 313856:313915|attR 324251:325043

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031942297.1\|273008_273977_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.5e-184	99.1
WP_000645320.1\|275453_275831_+	hypothetical protein	NA	NA	NA	NA
WP_000069824.1\|275922_276351_+	hypothetical protein	NA	NA	NA	NA
WP_001290639.1\|276415_276673_+	hypothetical protein	NA	NA	NA	NA
WP_000833775.1\|276828_277437_+	hypothetical protein	K4JV11	Caulobacter_phage	4.4e-25	38.5
WP_000104393.1\|277607_278858_+	site-specific DNA-methyltransferase	NA	NA	NA	NA
WP_000834113.1\|279152_279473_+	hypothetical protein	NA	NA	NA	NA
WP_000556022.1\|279715_280042_+	hypothetical protein	NA	NA	NA	NA
WP_001052325.1\|280107_280365_+	hypothetical protein	NA	NA	NA	NA
WP_000774871.1\|280594_281386_+	hypothetical protein	NA	NA	NA	NA
WP_022646497.1\|281436_281637_+	hypothetical protein	NA	NA	NA	NA
WP_000140246.1\|282721_283051_+	hypothetical protein	NA	NA	NA	NA
WP_001180999.1\|284866_285106_+	hypothetical protein	NA	NA	NA	NA
WP_000172888.1\|285168_285480_+	hypothetical protein	NA	NA	NA	NA
WP_000159617.1\|285476_285671_+	hypothetical protein	NA	NA	NA	NA
WP_012695484.1\|288849_289431_+	aminoglycoside N-acetyltransferase AAC(6')-IIc	NA	NA	NA	NA
WP_006473457.1\|289918_291274_+\|transposase	IS1380-like element IS1247 family transposase	A0A1X9I6F6	Streptococcus_phage	2.2e-45	29.7
WP_012695485.1\|291515_292325_+	AAC(3)-II family aminoglycoside N-acetyltransferase	O64018	Bacillus_phage	1.2e-17	29.3
WP_012695486.1\|292452_292866_+	NAD(+)--rifampin ADP-ribosyltransferase	NA	NA	NA	NA
WP_012695487.1\|293228_293660_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_000679427.1\|294969_295317_+	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_000259031.1\|295310_296150_+	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000050481.1\|296554_298096_+\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_004193276.1\|298771_299737_-	peptide ABC transporter permease SapB	NA	NA	NA	NA
WP_004193272.1\|299733_301377_-	peptide ABC transporter substrate-binding protein SapA	NA	NA	NA	NA
WP_004193269.1\|301677_302070_-	YdeI family stress tolerance OB fold protein	NA	NA	NA	NA
WP_004193267.1\|302201_302705_+	hypothetical protein	NA	NA	NA	NA
WP_004193264.1\|302714_303161_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_004193262.1\|303108_303687_+	2-oxo-tetronate isomerase	B5TK85	Pseudomonas_phage	2.0e-19	34.0
WP_004193260.1\|303863_304772_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	4.3e-77	53.0
WP_017900990.1\|304867_305512_-	quinolone resistance pentapeptide repeat protein QnrB4	NA	NA	NA	NA
WP_017900991.1\|305594_306584_-	phage shock protein operon transcriptional activator	NA	NA	NA	NA
WP_003020532.1\|306739_307408_+	phage shock protein PspA	NA	NA	NA	NA
WP_004193245.1\|307462_307687_+	envelope stress response membrane protein PspB	NA	NA	NA	NA
WP_004193243.1\|307686_308046_+	envelope stress response membrane protein PspC	NA	NA	NA	NA
WP_004193241.1\|308054_308285_+	phage shock protein PspD	NA	NA	NA	NA
WP_004236386.1\|309635_310775_-	class C beta-lactamase DHA-1	NA	NA	NA	NA
WP_004193231.1\|310885_311761_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025999322.1\|311764_312130_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_052238321.1\|312022_312358_+	ethidium bromide resistance protein	NA	NA	NA	NA
WP_134872535.1\|312351_313188_+	dihydropteroate synthase	NA	NA	NA	NA
WP_000376623.1\|313315_313816_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
313856:313915	attL	NA	NA	NA	NA
WP_001067855.1\|313891_314596_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_011977770.1\|314541_314973_-	hypothetical protein	A0A077SK32	Escherichia_phage	2.9e-55	97.3
WP_002903955.1\|316229_317132_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	2.6e-159	99.7
WP_002210513.1\|317393_318155_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.9e-134	100.0
WP_002904004.1\|318175_319036_-	class A extended-spectrum beta-lactamase SHV-12	A0A077SL40	Escherichia_phage	2.2e-155	99.3
WP_001067855.1\|319172_319877_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
WP_077249983.1\|320036_321545_+\|transposase	IS21-like element ISCfr8 family transposase	A0A2L1IVA1	Escherichia_phage	9.9e-26	32.7
WP_012695455.1\|321531_322272_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	4.4e-43	41.7
WP_032488579.1\|322499_323054_-	aminoglycoside N-acetyltransferase AAC(6')-Ib3	NA	NA	NA	NA
WP_138827841.1\|323230_324250_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	8.1e-72	45.5
WP_001067855.1\|324286_324991_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.8e-139	100.0
324251:325043	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP049188

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049188_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049188_1

3915190-3915294

Orphan

Consensus_repeat	Method
TGTCCCACCCTGTACCACTTTTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049188_1

>merge|NZ_CP049188|1|3915190-3915294|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTTAAACCAAATTCTCTGAGGTGGGACGCTGAAACTCGCGCCAGCTCTGCGTGTACCACTTGTCCCACCCTGTACCACCTTTTT

>NZ_CP049188|1|1|3915190-3915294|CRISPRCasFinder
TGTCCCACCCTGTACCACTTTTTT	AAACCAAATTCTCTGAGGTGGGACGCTGAAACTCGCGCCAGCTCTGCGTGTACCACT
TGTCCCACCCTGTACCACCTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049188.1\|WP_137048647.1\|3903386_3904895_-\|DUF4041-domain-containing-protein	unknown	unknown	gnl\|CDD\|214947
NZ_CP049188.1\|WP_045346115.1\|3922633_3923278_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049188.1\|WP_003863119.1\|3926212_3926500_+\|RnfH-family-protein	unknown	unknown	gnl\|CDD\|234982
NZ_CP049188.1\|WP_032609930.1\|3926561_3926900_-\|outer-membrane-protein-assembly-factor-BamE	unknown	unknown	gnl\|CDD\|183190
NZ_CP049188.1\|WP_045346134.1\|3902590_3903226_+\|3-hexulose-6-phosphate-synthase	unknown	unknown	gnl\|CDD\|132172
NZ_CP049188.1\|WP_045346135.1\|3901161_3902004_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|284075
NZ_CP049188.1\|WP_045346117.1\|3917998_3922471_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379062
NZ_CP049188.1\|WP_137048672.1\|3912293_3913274_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|226255
NZ_CP049188.1\|WP_003863115.1\|3925146_3925629_-\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NZ_CP049188.1\|WP_122974549.1\|3923279_3923444_-\|integrase	unknown	unknown	gnl\|CDD\|170049
NZ_CP049188.1\|WP_071524123.1\|3926881_3927064_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049188.1\|WP_006811645.1\|3925746_3926223_+\|type-II-toxin-antitoxin-system-RatA-family-toxin	unknown	unknown	gnl\|CDD\|182678
NZ_CP049188.1\|WP_101705291.1\|3914533_3914950_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP049188.1\|WP_137048676.1\|3913641_3914163_-\|PTS-sorbitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226253
NZ_CP049188.1\|WP_137048670.1\|3911260_3912283_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP049188.1\|WP_045346118.1\|3917420_3917636_-\|AlpA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225848
NZ_CP049188.1\|WP_164474407.1\|3915315_3917385_-\|DUF927-domain-containing-protein	unknown	unknown	gnl\|CDD\|227806
NZ_CP049188.1\|WP_137048674.1\|3913270_3913645_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226254
NZ_CP049188.1\|WP_164474406.1\|3905302_3911029_+\|NACHT-domain-containing-protein	unknown	unknown	gnl\|CDD\|368582
NZ_CP049188.1\|WP_045346178.1\|3902003_3902567_+\|6-phospho-3-hexuloisomerase	unknown	unknown	gnl\|CDD\|132171

Protein	Function_ID	Function_description	E-value
NZ_CP049188.1\|WP_137048647.1\|3903386_3904895_-\|DUF4041-domain-containing-protein	gnl\|CDD\|214947	smart00974, T5orf172, This entry represents the putative helicase A859L.	4.603e-22
NZ_CP049188.1\|WP_003863119.1\|3926212_3926500_+\|RnfH-family-protein	gnl\|CDD\|234982	PRK01777, PRK01777, RnfH family protein.	7.87688e-48
NZ_CP049188.1\|WP_032609930.1\|3926561_3926900_-\|outer-membrane-protein-assembly-factor-BamE	gnl\|CDD\|183190	PRK11548, PRK11548, outer membrane protein assembly factor BamE.	1.15968e-81
NZ_CP049188.1\|WP_045346134.1\|3902590_3903226_+\|3-hexulose-6-phosphate-synthase	gnl\|CDD\|132172	TIGR03128, RuMP_HxlA, 3-hexulose-6-phosphate synthase. Members of this protein family are 3-hexulose-6-phosphate synthase (HPS), or the HPS domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin. In these species, the enzyme is viewed as a lyase rather than a synthase and is called D-arabino 3-hexulose 6-phosphate formaldehyde lyase. Note that there is some overlap in specificity with the Escherichia coli enzyme 3-keto-L-gulonate 6-phosphate decarboxylase.	3.88509e-95
NZ_CP049188.1\|WP_045346135.1\|3901161_3902004_+\|hypothetical-protein	gnl\|CDD\|284075	pfam06560, GPI, Glucose-6-phosphate isomerase (GPI). This family consists of several bacterial and archaeal glucose-6-phosphate isomerase (GPI) proteins (EC:5.3.1.9).	4.43983e-86
NZ_CP049188.1\|WP_045346117.1\|3917998_3922471_-\|ATP-binding-protein	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.00225912
NZ_CP049188.1\|WP_137048672.1\|3912293_3913274_-\|PTS-glucitol/sorbitol-transporter-subunit-IIB	gnl\|CDD\|226255	COG3732, SrlE, Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism].	2.72197e-174
NZ_CP049188.1\|WP_003863115.1\|3925146_3925629_-\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	3.42148e-87
NZ_CP049188.1\|WP_122974549.1\|3923279_3923444_-\|integrase	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	5.37204e-13
NZ_CP049188.1\|WP_006811645.1\|3925746_3926223_+\|type-II-toxin-antitoxin-system-RatA-family-toxin	gnl\|CDD\|182678	PRK10724, PRK10724, type II toxin-antitoxin system RatA family toxin.	2.40602e-112
NZ_CP049188.1\|WP_101705291.1\|3914533_3914950_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.88377e-05
NZ_CP049188.1\|WP_137048676.1\|3913641_3914163_-\|PTS-sorbitol-transporter-subunit-IIC	gnl\|CDD\|226253	COG3730, SrlA, Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism].	7.06218e-77
NZ_CP049188.1\|WP_137048670.1\|3911260_3912283_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.16412e-67
NZ_CP049188.1\|WP_045346118.1\|3917420_3917636_-\|AlpA-family-transcriptional-regulator	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	1.06623e-20
NZ_CP049188.1\|WP_164474407.1\|3915315_3917385_-\|DUF927-domain-containing-protein	gnl\|CDD\|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
NZ_CP049188.1\|WP_137048674.1\|3913270_3913645_-\|PTS-glucitol/sorbitol-transporter-subunit-IIA	gnl\|CDD\|226254	COG3731, SrlB, Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism].	1.54797e-56
NZ_CP049188.1\|WP_164474406.1\|3905302_3911029_+\|NACHT-domain-containing-protein	gnl\|CDD\|368582	pfam05729, NACHT, NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.	2.27324e-06
NZ_CP049188.1\|WP_045346178.1\|3902003_3902567_+\|6-phospho-3-hexuloisomerase	gnl\|CDD\|132171	TIGR03127, RuMP_HxlB, 6-phospho 3-hexuloisomerase. Members of this protein family are 6-phospho 3-hexuloisomerase (PHI), or the PHI domain of a fusion protein. This enzyme is part of the ribulose monophosphate (RuMP) pathway, which in one direction removes the toxic metabolite formaldehyde by assimilation into fructose-6-phosphate. In the other direction, in species lacking a complete pentose phosphate pathway, the RuMP pathway yields ribulose-5-phosphate, necessary for nucleotide biosynthesis, at the cost of also yielding formaldehyde. These latter species tend usually have a formaldehyde-activating enzyme to attach formaldehyde to the C1 carrier tetrahydromethanopterin.	6.06782e-82

>NZ_CP049188.1|WP_101705291.1|3914533_3914950_+|helix-turn-helix-transcriptional-regulator
MSKKDNQFFDQDNNFQFGTRLAEAMSLSEDTVSSLVDKTGIPNSTIRSYLKGESVPGIMQLRKIAAGMGIKAGWFLGDDEEFACPKDGISEIEKDLELLNNLFKYMAPVQRGRVLKRVLASVARQIEHNVDGDNNTEQ
>NZ_CP049188.1|WP_137048676.1|3913641_3914163_-|PTS-sorbitol-transporter-subunit-IIC
MWTVSLAEAFIHVFQTAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTIRMEKVAALLGRSRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSSRGNAP
>NZ_CP049188.1|WP_137048674.1|3913270_3913645_-|PTS-glucitol/sorbitol-transporter-subunit-IIA
MMIYCARIVAIGLFVADGLTDKMLITFDSNGPKDCLDYSLSLEPSFREESLMILPGDRLLLAGHDYLVTAVGKGAQQALFELGHLTLVFNGDLNPCHVGAVHLSGPVPNLRDLHGNLVIEEGRP
>NZ_CP049188.1|WP_137048672.1|3912293_3913274_-|PTS-glucitol/sorbitol-transporter-subunit-IIB
MNTVLIPPGPGGYGKGLWLPVGSGKKVLSLTEREIHPVAIEIGALTESEIVNGFSDIPPDNDILCVVINCAGSLRCGLYPQKGIPTINVLPTWRAGPLAHFISEDNYVSGVTMEQLVLVDTADVPDSEPEAMPEPAPRVITTPPPARGAEKLVRMVEQTGTAVGHVIALLFAASREAVDVSLRNVIPFMAFVSLLIALVQETALGSLIAHALTPLANSLWGLVLLSLICGIPFLSPVLGPGAAISQVIGVMIGTQIGAGTISPAFALPALFAINVQVGCDFVPVGLSMQEAKPETIAKGVPAFLLSRQLTGPLAVIIGWLFSLGLF
>NZ_CP049188.1|WP_137048670.1|3911260_3912283_-|Gfo/Idh/MocA-family-oxidoreductase
MNKIRAAVVGAGIYGRHHMNAYRHSPDTVLVAICDTDTERCDDLAMAYGVIGYTRLDALLQEEAIDVVSMATPDPYHTESILTALRHGKHVLAEKPLATSVRECELIVEMAQQRDLLVGVDFHKRWDPAVMRIKAELEKPEAGRILRGHISMDDVITVPTEWLDWAGASSPVWFLGSHCFDLVRHLSGQEVVSVYAVGQKQLMVECGLDTFDSVQSLLTMADGSSWVVENSWVLPEGFPKDNDGRIDILCEATYIRSSSQHRGLEITTPGMTLTPNSYFINYRNGVASGFGIDPINDFVRAVRHKAPYPVTAEDGLAVSRICEAVHRSLESGKPEHPTKP
>NZ_CP049188.1|WP_164474406.1|3905302_3911029_+|NACHT-domain-containing-protein
MAIKNSAIIYAGYDYQTLQGVRLLADWLNIPTKYNRIAFEADAKKIDAPQGIDDIVCERQDGKTDFWQVKFTPDTDKEDNQLSWEWLLKSSGHSLRSRSILQKIADAVDKVPAERRGNITLLTNKIPSREMAICLRNNIIVWNQVPVTKQQKIITQLGSLERAKKFFNLLQVHHSDQSYTRLNSIVPELLRKHTNEEGVYRLIERAKRWAIQRNSPSDDGWIYLEHIRSVISTNRPEPIPQTFVVPDNYIVPDADFHEKFIGLIFNPINRLVVLTGAPGKGKSTYISHICQILKAREYPYIRHHYFLGLDDRTVDRLSPRVVAEDLMSQVKVFCPQIEMKNYYAEHLHKVLAECGRIYEEEGKQFFVIIDGLDHVWRDNGKDKSPLDELFCQLLPLPDNVTLLVGTQPVDDELLPSRLLQNSPRKKWLHLPNMSGDAIRIYLSGQVESGRIIFNFHQSQYEEVLSQCAELLTTKTQGYPLYVIYSCEKLHIEGKRLSLWEIENLPDCEGGNITNYYNELWKTLSYEQRDILHLCCEFPFLWPETSFSEIFSESAEIIPNVKAVIHLLYESIAGLRPFHESLIVFIRSTTEHENRIKMLLPALISWLEKSAPEPIKNCWYWSCVACNGDPYPLRNGLTRDWILERLAEGYRQDEFIRLLTQAETSALAEGHFHEAYQHRSRKTRLLNARLQIWDMSTLGVCSMINASEALLKQYQSTQNISSPKILATLAIALWFRNSFDEAKRITRLALQRYSNESSVYTNKNSDESRADIRLLIKSAVLTECFEEKWLESGSVHKWGDSNINLLIECAEYKADIGFLFALHNIFNQGGIKDKIVNAIVRVGIVEKIDLEYWPRFSDLDSALLRLYSHLSIAYPCSLITEQGESEIGRYHIHPEVSYDEWFYESLSYRLNASGNYCWLPVSPEEGLEEVSNHFHHLNDFSDIIAESMALNIKQSFSDFCDLIALASDLKDHQMQIQQKRMFFKTDWVNIALNLHLIMHCKPVNREEINIVLNSEHTALYRLHKTILNFHSRAFESEAIANFLVFEDERQKEKLQETNEYLANNLELSEIALHYDLNQSNFFERVKLCWDYGLGYGHHKDISLNQALTAIETIAAVEPKYALTQLERVSPLVDNICDFTDGDHTQHSVTEMSALYARLSPLILSSIYDSYVSEGEWYDADNALTQYLKHADLSSPFVESLCLTLLDDGQIEIVRSRIKDSSVLTTFWPEILPQKIDCSNIVDSSLKSVDYFEPAKIRPTDVTNLLNTRSGYDNIPKWYHYWKDQGKVIDLINVLLPIINDGLPKYSEFRYILSDLFEDTLRLKGKKYAFPILVQEHIQRNGWGEWGESDDQTYARLDKVAILYPDKIDDFICKTTRLHYYKTKEDNLVIPGNRLTYLLVKVGRVDEAKSLCEAMISELEAETRNLPLCKPQWQWEGELDNDMIAVKFIIRRLFWPVQCVKHLVAEQLSHILANSKRAEDIENLLATEMRNRQLESEVVDILTVFWLASLKGYKVQNNISSFICARSFLSDILLESIAPNLPNLSCYQVLHKHPDDSNHYGFEKILGNDLPHIFWDEIKRLEDKSGIPAKRLMKKEWSDICHNHIQRWERVDYFFGSERDGFTMSFSTRNTRFGISAYLRTINRIIAEFRMPKDYAEHYSACLMSANPLFYSVSNHRPDWLPSWQYGAITTKENIKSYIEECLKEFKNENNNLMLGALSLPIRIDENNWLDITIVMGIQTEEHVSFKIQYADCGHSIDSLLQTYRNIEFSLAKWAEYKNCVPLLGSTGELLRIARWDIMYEFRGLFSLCCQEQVTAYPAKDYINFDYQGNTIGYSDFWQAIPLSIYPKDIRSPVATYTAYDKDLAYKWNNHSVLKKPNIMLCDCKVLKRENSYTPFETSDIRFHFESEPL
>NZ_CP049188.1|WP_137048647.1|3903386_3904895_-|DUF4041-domain-containing-protein
MNMVYLSATALTVAVLSVVIVFVLLTKLRAVKASDASKTAQLERYAVISDAETEATRIAQEAEQQAREIIGCAKGTATSLEEEATALLSNAQSTTLSLQDQITSLRASYAEKKSIYDELEKAIALYREDVDFAEMGMFEPHFDFDTSEEFKEAIKDNRNEQKALLRLKNQAGAIWCGTDWTVHNSRAEGKKMTTRAINLTARAFNGECDAAIANCTFKNWSVMHDRIQAAFNKINALNEVNDVHISKEYLRLKLKELDLVHAYKMKKQSEKEEQREIRAQMAEERKAQQEIERAIREAEAEEVRAQKALDKARKEMESKLAQLTTEQAEKYQSKIDELRDALTEAELKGQKALSMAQQTKRGHVYVISNVGSFGEDVFKIGMTRRLDPQDRVDELGSASVPFLFDVHAMIHSEDAPALENALHQHFDAKRTNLVNRRKEFFNVSLKEIKSAVYELAGNDVDFIETVVAQHYYETLALRNKQSGAAGVQARNTTVLPRFAESI
>NZ_CP049188.1|WP_045346134.1|3902590_3903226_+|3-hexulose-6-phosphate-synthase
MKLQLALDELTLPEALAFIDKVVDDVDIIEVGTPFLIREGVNAIKAIKEKYPHKEVLADAKIMDGGHFESQLLFDAGADYVTVLGVTDVLTIQSCIRAAKEVGKQVVVDMICVDDLPTRVRLLEEAGADMLAVHTGTDQQAAGRKPIDDLITMLKARRKARIAVAGGISSQTVKDYALLGPDVVIVGSAITHAVDPAVEARTISQVLLQHR
>NZ_CP049188.1|WP_045346178.1|3902003_3902567_+|6-phospho-3-hexuloisomerase
METQSVAGVACSDLNQAMSRIDGAALACLEQAIADANAIFVFGAGRSLLMLKAFAMRLMHIGLKVHVVGDVVTPALQKGDLLLLASASGETASLVNVATKAKQLGGTVALLTIFPESTLGKLADVVVRIPAYTDKLPDGPDNVKGILPGGSLFEEAVMVLGDAMIVNLAQSTGYRLTKGFALHANLE
>NZ_CP049188.1|WP_045346135.1|3901161_3902004_+|hypothetical-protein
MKQLHHSGLPLYLDDDGVMALKPPLNYLGFGRKSAGQMAVVLPEFTEALCDEPAYDVYRGLCFPEDQERLAADQYQYDITIIMPGTIGKERKKTSGHYHGYNDTRRNTHPEVYEVIKGTAAYILQKSPDFAVEPKDLLVDDLIVAVVKEGQSIIVPPNYGHCSINIGDGPLVFSNLAYKPCAVHYDTVQFYHGMACYIVEENGQLCVRKNHYYPHIPRIKFATVKENPHLGITFDTPLYQRYRAAPERFYFLGHVDNYVREIMGMLQYQDDLFPLCQEDA
>NZ_CP049188.1|WP_164474407.1|3915315_3917385_-|DUF927-domain-containing-protein
MKRAPFLCKQSPDRTLEVVILAGSLAWETSRAWRKDPDREDDVPPVVLGPDELADLANLTIIRPDTLYVRVLRTGDIREEDLMKIAVKLAHAGVQMARLMTPDGELLENWTGQLARLRQERPSDILPDHFRLDEEALWFDKFTERRDGESDVQSQRICSPLRVTAITCDSHDGSYGRLLEWHTTTGQLRRWAMPMAMLSGNGEELRRILLENGLTYISTRPALRSLLCEYISRSLPGRRVTCVEKTGWHNGVYVLPDEVIGPDGDNVILQGSHYLTGGFAQSSTLAEWQEQVAALCAGNSRLVFAVCCALAAPLLRLTGTGGGGFHLRGESTDGKTTVMKVAASVCGGTDYWHSWRATGNALEGIASRHNDALLPLDELREVDPREAGMIAYMLANGQGKGRARTDGEVRNRRHWTLLLFSTGELSLAEHTERAGERLYAGMDVRMVQIPSDTGQHGAFEQLHGFASGQQFADALCDRVARFHGTAFRALLAFLTHDQDDNIALARELLRRYQTALMPEHAGNQVQRIVARFALLAVAGEIATLQGITGWQEGTAYEAVRICLHAWLNERGHIANQEDEGVLAQIKRFITAHQYSRFASWDGPDRPLNMVGFRRVEKDPLTGEEHTLFHILPEGWREMCRGFSPARAARLCQEAECLLPGSEGKYQSQVRLPEIGKARVYRLTSRILSI
>NZ_CP049188.1|WP_045346118.1|3917420_3917636_-|AlpA-family-transcriptional-regulator
MKTLADNNDAFPESGNVRMRQVVQFLAMSESSVYRLIKNTDFPRPVHLSSRLVVFDAAEIRQWQQRRTAIR
>NZ_CP049188.1|WP_045346117.1|3917998_3922471_-|ATP-binding-protein
MDPISVTTVSIYVATKFIDQFIAEEGYGWLKKKLFPKNNYVNQLYRIIEETAIEFEKKFPIDSIKIPFYQSQLLFETLNEHILFKELPDKDYLLQKFSEYPNVIPPTQEQLETFYKIFLLKINNCKELKKLHIEETYKDKIFDVSNEIIQIKLLLQSFDEKFTFHLNDNWLNNKNREAIADLGGRYTPELNLKLEIADIFEGLGKTNKFSKIFYEHIDNFLIKGNNLRNCDEIREQLALISKALTDTSILFLKIDFHESKSIPINKFNEYISNCQKYISEAESTLWKIKEKENPDKTTSFSDKYSSILRDLREFYYECDTLYIFLNSITVKLSNNPFLLLEGEAGIGKSHLLADIIESRIQTGYPSLFLLGQQLTTDESPWVQILKRLQLNTVSSEFLEKLNLYGEKQGKRFLIFIDAINEGNGNIFWEDNINSFVDEIRSFKWLGLIISVRSTYKDITISNERISRNNFEIYEHLGFKNKEMEAVNLFYDNYNIERPSSPNLNPEFKNPLFLKLLCEGIKKSGLKKVPVGFHGISKILSFFVEGVNKSLSSHKRYNFDPSFPLVSDALNKLIKVKLANGRNSIALKDAHTAVQSVVKDYVNDKTFLSSMIDEGILTKGIVRNEDNSVEEVVYISFERFDDHLTVNYLLNGVDNIEDEFKTGGSLQKYFNDEYSFYRNQGIIEALSIQSPEKYGKEIYELLPNYSDNYNLVTAFIDSLVWRDSAAIDFEKIKPFVNKQVLGFDNSFSHFLETLISISGLEEHPFNANFLHNWLLQHSLPNRDAFWTTALKYRYSEDSAFKNLIDWAWSGTDKSYISDDSIELVATTLCWFLTSTNRELRDCTTKALVNLLEERISVLIRIINKFDGINDPYVWERVFAVALGCTLRTKNHNKLSQLAETVFAKVFQPKYVYPHILLRDYAREIIEYVSHLQLIPEGLDLSKTKPPYKSKWPENIPTKEELQSLYKKDGYWSLWGSIMGGGDFSRYIIGTNHNHSNWSGCKFGETPINRKKIFNDFLGQLSDEQKALYDSTDPIIYDKNYKSISFGNTLIKYGVAIGRKSEEEVLSHKSVFKKSLSEDLLATFERDIEKYLDHNNNLLETDKYFDLRIAERMIFNRVINLGWDPKLHGDFDKQVGSGRGRRESLQERIGKKYQWISYYEYMAMLSDNFIRFDGYGDERKENPYQGPWDPYVRDIDPTILIKNTGTKELTQQEMWWDTKEVFDWDCTFQEWVSNPSTISNPYGLIEVNDNNGTEWLILESYPSWKEPKTIGNEEWGHPRKEVWCQIRGYLVRTTELNALKNWAENQHYMGRWMPEGSNRYQLFNREYYWSEAFHYFKSDYYGSLDWSSVTDQDSGAKIADVSVTSINYLWEEEFDKSKTDTLSFLKPTSLIFDKMGLKDGKYEGSYEDKYGSIVCFATEALNNSKAHLLIKKEPFLKMLNENNLEIVWTLLGEKGVIGGSLSSIHQYGRIEFSGFFSYDDGKLTGANKIYSS
>NZ_CP049188.1|WP_045346115.1|3922633_3923278_-|hypothetical-protein
MTSPIRQNLFERECDMPLLEARHLALLLLGLDASQPANALPEEHQENYRILHDAISRTIKATGMVSAPANKRMFYADEMFALAWRLIDDELTPPEIKARSLKAVMKLSRNSRGRKWLKTLGDDALPDLTTSAQPSQRGMHKRDKARENTARLCWLLVQLLVEETDGRYGTSDKPTSDRILRKLRALAQERELPSDGLGRGTFYEVLKMGREKEK
>NZ_CP049188.1|WP_122974549.1|3923279_3923444_-|integrase
MAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGEEEPLRIVEGE
>NZ_CP049188.1|WP_003863115.1|3925146_3925629_-|SsrA-binding-protein-SmpB
MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAFLFGANFTPLTVASSHYVCDPTRTRKLLLNKRELESLYGRINREGFTVVALSLYWKNAWCKVKIGVAKGKKQHDKRTDLKAREWQLDKARIMKNAGR
>NZ_CP049188.1|WP_006811645.1|3925746_3926223_+|type-II-toxin-antitoxin-system-RatA-family-toxin
MLLFVCCVTMENAMPQISRTALVPYSAEQMYQLVNDVQSYPEFIPGCTGSRVLESGPTQMTAAVDVSKAGISKTFTTRNTLTSNQSILMHLVDGPFKKLMGGWKFTPLSADACRIEFHLDFEFTNKLIELAFGRIFKELASNMVQAFTTRAKEVYSVA
>NZ_CP049188.1|WP_003863119.1|3926212_3926500_+|RnfH-family-protein
MSHKIAVEVVYALPEKQYLQRVTLEEGATVEAAIRASGILELRRDIDLAKNKVGIYSRPVKLGDVLKEGDRVEIYRPLIADPKELRRQRAEKSGK
>NZ_CP049188.1|WP_032609930.1|3926561_3926900_-|outer-membrane-protein-assembly-factor-BamE
MRCKTLTAAAAVLLMLTAGCSTLEKVVYRPDINQGNYLTPNDVSKIRVGMTQQQVAYALGTPMMSDPFGTNTWFYVFRQQPGHEDVTQQTLTLTFSSGGVLTNIDNKPALTK
>NZ_CP049188.1|WP_071524123.1|3926881_3927064_-|hypothetical-protein
MRKNCWRHKLFRDLRVIQNNKNAARPVSKWGKVYYHRHITYEPRTARARKGIKSLCAVKR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

109087 : 148631

uncultured_Caudovirales_phage(37.5%)

integrase,transposase,tRNA,plate

attL 99197:99213|attR 152072:152088

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
99197:99213	attL	NA	NA	NA	NA
WP_137048704.1\|109087_110428_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_050870678.1\|110424_111114_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_164474173.1\|111110_112817_+	OmpA family protein	NA	NA	NA	NA
WP_009653685.1\|112822_113314_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_164474174.1\|116123_118616_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	8.7e-19	33.1
WP_164474175.1\|118869_120801_+	DUF3274 domain-containing protein	A0A077K801	Ralstonia_phage	1.8e-59	29.8
WP_072049647.1\|120999_121623_+	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_045350043.1\|121624_122674_+	hypothetical protein	NA	NA	NA	NA
WP_126814974.1\|122663_122879_+	hypothetical protein	NA	NA	NA	NA
WP_047654422.1\|124689_124953_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_160859203.1\|124952_126383_+	hypothetical protein	NA	NA	NA	NA
WP_164474176.1\|126388_129787_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_164474177.1\|129786_131388_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_023324761.1\|131429_133184_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_023324760.1\|133147_134233_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_045333095.1\|134210_134756_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_050870517.1\|134755_135211_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_164474178.1\|135234_136551_+	hypothetical protein	NA	NA	NA	NA
WP_023314232.1\|136579_137068_+	hypothetical protein	NA	NA	NA	NA
WP_164474179.1\|137384_138515_+	chemoreceptor protein	A0A2H4J162	uncultured_Caudovirales_phage	2.6e-10	28.6
WP_023314230.1\|138605_139589_+	zinc transporter ZntB	NA	NA	NA	NA
WP_015570430.1\|139863_140016_+	hypothetical protein	NA	NA	NA	NA
WP_045337431.1\|140073_141447_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	3.6e-51	31.9
WP_164474180.1\|141490_142426_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	2.3e-142	96.1
WP_112778021.1\|142942_144000_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	4.8e-128	74.7
WP_164474181.1\|144343_145225_-	arginase family protein	NA	NA	NA	NA
WP_023314223.1\|145262_146357_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_023314222.1\|146459_147344_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045346248.1\|147432_148104_-	SOS response-associated peptidase	A0A2H4J5W2	uncultured_Caudovirales_phage	4.2e-77	59.5
WP_071785691.1\|148430_148631_-\|integrase	tyrosine-type recombinase/integrase	A0A0U2JGI6	Escherichia_phage	1.1e-20	71.7
152072:152088	attR	NA	NA	NA	NA

DBSCAN-SWA_2

779584 : 843261

Klebsiella_phage(28.57%)

capsid,tRNA,tail,integrase,portal,head,terminase

attL 813433:813450|attR 842491:842508

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022650816.1\|779584_780085_+\|tRNA	YbaK/prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_022650815.1\|780494_781826_+	hypothetical protein	NA	NA	NA	NA
WP_164474240.1\|781841_783878_+	glycoside hydrolase family 31 protein	NA	NA	NA	NA
WP_003857881.1\|783984_784431_+	DUF441 domain-containing protein	NA	NA	NA	NA
WP_022650813.1\|784414_785206_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_022650812.1\|785305_786493_+	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_022650811.1\|786524_787232_-	CTP synthase	NA	NA	NA	NA
WP_003857886.1\|787382_787727_+	DUF488 domain-containing protein	NA	NA	NA	NA
WP_058674976.1\|787727_788033_-	hypothetical protein	NA	NA	NA	NA
WP_022650809.1\|788113_788368_-	DUF333 domain-containing protein	NA	NA	NA	NA
WP_023315855.1\|788680_789709_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	5.0e-13	32.1
WP_015570793.1\|789754_789853_+	YoaK family small membrane protein	NA	NA	NA	NA
WP_015570794.1\|789853_789928_+	protein YoaJ	NA	NA	NA	NA
WP_003857896.1\|789981_790230_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_071524166.1\|790600_790693_+	stress response membrane protein YncL	NA	NA	NA	NA
WP_045345722.1\|790817_792317_+	EAL domain-containing protein	NA	NA	NA	NA
WP_022650806.1\|792321_792567_-	YmjA family protein	NA	NA	NA	NA
WP_045351080.1\|792642_792834_-	hypothetical protein	Q77Z09	Phage_21	2.7e-21	92.6
WP_045351079.1\|792978_794277_-	DUF2254 domain-containing protein	NA	NA	NA	NA
WP_042863324.1\|794342_796340_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	2.6e-21	26.2
WP_058663376.1\|796542_797100_-	recombinase family protein	A0A1S6L009	Salmonella_phage	2.1e-74	76.5
WP_058663334.1\|797230_797971_+	hypothetical protein	G8C7K5	Escherichia_phage	2.1e-90	69.0
WP_042863383.1\|797936_798515_-\|tail	tail fiber domain-containing protein	A0A2I6PD03	Escherichia_phage	8.7e-47	54.5
WP_010429924.1\|799102_799336_-	hypothetical protein	E4WL42	Enterobacteria_phage	3.9e-30	76.6
WP_164474241.1\|799443_800115_-	hypothetical protein	A0A2P0WA07	Enterobacter_phage	1.8e-83	70.9
WP_042863330.1\|800115_800430_-	hypothetical protein	A0A2P0WA17	Enterobacter_phage	3.7e-36	71.6
WP_042863333.1\|803983_804586_-\|tail	tail assembly protein	I6PCW4	Cronobacter_phage	6.9e-47	52.6
WP_058663337.1\|804566_805283_-	peptidase P60	A0A1W6JP31	Morganella_phage	4.1e-62	47.4
WP_058663338.1\|805285_806035_-\|tail	phage minor tail protein L	K7PGX3	Enterobacteria_phage	3.2e-86	58.4
WP_163354931.1\|806117_806477_-\|tail	phage tail protein	A0A1W6JP11	Morganella_phage	7.8e-22	42.2
WP_058663339.1\|806473_809446_-\|tail	phage tail tape measure protein	A0A2H4J107	uncultured_Caudovirales_phage	3.3e-25	25.4
WP_042863338.1\|809435_809654_-	hypothetical protein	Q6UAW9	Klebsiella_phage	1.7e-08	42.3
WP_010433126.1\|809674_810019_-	hypothetical protein	NA	NA	NA	NA
WP_042863340.1\|810077_810551_-	hypothetical protein	NA	NA	NA	NA
WP_042863384.1\|810568_810973_-	hypothetical protein	Q6UAX1	Klebsiella_phage	1.6e-39	66.4
WP_042863341.1\|810984_811365_-	hypothetical protein	Q6UAX2	Klebsiella_phage	1.0e-43	71.1
WP_042863343.1\|811345_811687_-\|head,tail	head-tail adaptor protein	Q6UAX3	Klebsiella_phage	1.3e-37	66.4
WP_042863344.1\|811683_812007_-\|head,tail	phage gp6-like head-tail connector protein	Q7Y407	Yersinia_phage	2.0e-32	64.2
WP_058663340.1\|811987_812440_-	hypothetical protein	Q6UAX5	Klebsiella_phage	1.2e-14	65.0
WP_042863346.1\|812499_813795_-\|capsid	phage major capsid protein	Q6UAX6	Klebsiella_phage	4.9e-175	74.4
813433:813450	attL	NA	NA	NA	NA
WP_042863347.1\|813863_814781_-	S49 family peptidase	Q6UAX7	Klebsiella_phage	7.9e-111	68.2
WP_058663341.1\|814814_816074_-\|portal	phage portal protein	Q6UAX8	Klebsiella_phage	4.8e-191	77.2
WP_010433111.1\|816073_816253_-	hypothetical protein	Q6UAX9	Klebsiella_phage	3.3e-05	49.1
WP_042863349.1\|816246_817962_-\|terminase	terminase large subunit	Q6UAY0	Klebsiella_phage	2.4e-278	79.3
WP_042863351.1\|817996_818431_-\|terminase	P27 family phage terminase small subunit	Q6UAY1	Klebsiella_phage	5.5e-62	80.6
WP_045351068.1\|818568_818928_-	HNH endonuclease	Q6UAS2	Klebsiella_phage	3.0e-50	73.3
WP_045351067.1\|819302_819623_+	hypothetical protein	NA	NA	NA	NA
WP_052686676.1\|820094_820532_-	hypothetical protein	NA	NA	NA	NA
WP_045351066.1\|820666_821104_-	hypothetical protein	NA	NA	NA	NA
WP_045351065.1\|821432_821972_-	hypothetical protein	K7PHH7	Enterobacteria_phage	5.6e-72	78.9
WP_045351064.1\|821968_822505_-	lysozyme	K7PM52	Enterobacteria_phage	1.1e-80	79.4
WP_023292747.1\|822504_822720_-	hypothetical protein	H9C183	Pectobacterium_phage	1.0e-24	75.4
WP_058663377.1\|823948_824554_-	hypothetical protein	H9C175	Pectobacterium_phage	2.5e-81	72.0
WP_058663343.1\|824566_825586_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.0e-95	51.6
WP_032658080.1\|826049_826304_-	cloacin	NA	NA	NA	NA
WP_072052043.1\|826313_827891_-	hypothetical protein	NA	NA	NA	NA
WP_080337586.1\|828174_828408_-	hypothetical protein	H6WRY6	Salmonella_phage	3.3e-21	66.2
WP_058663344.1\|828446_828680_-	DinI-like family protein	K7PM44	Enterobacteria_phage	3.2e-24	71.4
WP_058663345.1\|829028_829403_-	hypothetical protein	M9NZE4	Enterobacteria_phage	5.3e-13	53.8
WP_047353897.1\|829402_829735_-	hypothetical protein	NA	NA	NA	NA
WP_058663346.1\|829731_829992_-	DUF977 family protein	H6WRX9	Salmonella_phage	4.9e-26	68.7
WP_023303444.1\|829995_830415_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_080337585.1\|830429_831101_-	replication protein	A0A0U2JGJ0	Escherichia_phage	6.1e-68	77.5
WP_058663348.1\|831981_832536_-	hypothetical protein	M9NZI6	Enterobacteria_phage	2.4e-14	33.0
WP_040017166.1\|832538_832769_-	Cro/Cl family transcriptional regulator	H6WRX5	Salmonella_phage	8.0e-20	60.5
WP_080317437.1\|832858_833296_+	helix-turn-helix domain-containing protein	H6WRX4	Salmonella_phage	1.6e-37	59.0
WP_154817221.1\|833657_833972_-	hypothetical protein	NA	NA	NA	NA
WP_071785721.1\|836858_837104_+	excisionase	NA	NA	NA	NA
WP_058663350.1\|837084_838218_+\|integrase	tyrosine-type recombinase/integrase	O21925	Phage_21	2.1e-121	58.8
WP_126680790.1\|838250_839441_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_003857898.1\|839604_840855_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	7.9e-21	94.4
WP_022650805.1\|840972_841635_+	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_022650804.1\|841634_842108_+	NUDIX hydrolase	NA	NA	NA	NA
WP_032628201.1\|842148_843261_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
842491:842508	attR	NA	NA	NA	NA

DBSCAN-SWA_3

4407195 : 4413473

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061856589.1\|4407195_4408587_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	2.2e-19	32.3
WP_017383282.1\|4408761_4409658_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	1.8e-43	42.2
WP_032659367.1\|4410017_4411103_+	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	3.7e-99	51.5
WP_045617132.1\|4411102_4412002_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	9.7e-29	35.0
WP_045341336.1\|4412054_4412933_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.9e-107	64.5
WP_045350274.1\|4412936_4413473_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	1.5e-53	57.2

DBSCAN-SWA_4

4436165 : 4446493

Stx2-converting_phage(16.67%)

integrase

attL 4427180:4427195|attR 4437371:4437386

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4427180:4427195	attL	NA	NA	NA	NA
WP_045617126.1\|4436165_4437344_+\|integrase	site-specific integrase	K7P703	Enterobacteria_phage	1.1e-221	93.6
WP_045346713.1\|4437324_4437516_-	AlpA family phage regulatory protein	A0A0P0ZBL0	Stx2-converting_phage	5.4e-30	93.7
4437371:4437386	attR	NA	NA	NA	NA
WP_164474429.1\|4437664_4437877_+	hypothetical protein	NA	NA	NA	NA
WP_047653465.1\|4437960_4438230_-	hypothetical protein	NA	NA	NA	NA
WP_137048456.1\|4438320_4438539_-	TraR/DksA family transcriptional regulator	A0A0N7C211	Escherichia_phage	6.6e-16	60.6
WP_045618254.1\|4438630_4438822_-	DUF1382 family protein	A0A0P0ZC60	Stx2-converting_phage	4.1e-14	66.1
WP_047653463.1\|4438818_4439430_-	hypothetical protein	NA	NA	NA	NA
WP_045618256.1\|4439426_4439645_-	hypothetical protein	NA	NA	NA	NA
WP_045350982.1\|4439641_4440193_-	phage N-6-adenine-methyltransferase	E5AGF8	Erwinia_phage	1.8e-54	57.7
WP_164474430.1\|4440189_4440357_-	hypothetical protein	G8C7S7	Escherichia_phage	3.1e-21	94.4
WP_058657408.1\|4440771_4441395_-	YqaJ-like viral recombinase	S0A2A9	Cellulophaga_phage	2.1e-46	49.5
WP_162269524.1\|4441391_4441673_-	hypothetical protein	A0A0F7L7F5	uncultured_marine_virus	3.6e-06	30.0
WP_052686700.1\|4441929_4443303_+	hypothetical protein	K4I6L2	Salmonella_phage	9.6e-161	58.2
WP_045617706.1\|4443330_4444791_-	hypothetical protein	NA	NA	NA	NA
WP_045617705.1\|4444787_4445717_-	glycosyltransferase family 2 protein	U5P087	Shigella_phage	6.5e-161	92.4
WP_045617703.1\|4445713_4446076_-	GtrA family protein	U5P0S6	Shigella_phage	1.7e-48	80.8
WP_045617702.1\|4446187_4446493_+	hypothetical protein	I6PCW5	Cronobacter_phage	7.8e-15	39.6

DBSCAN-SWA_5

4611629 : 4619104

Ralstonia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048240583.1\|4611629_4614143_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.2e-14	27.8
WP_063961245.1\|4614139_4616254_+	DUF3274 domain-containing protein	A0A077K801	Ralstonia_phage	6.7e-20	29.5
WP_088567057.1\|4616278_4616971_+	hypothetical protein	A0A077K9W3	Ralstonia_phage	3.4e-05	58.1
WP_039264792.1\|4616974_4617682_+	hypothetical protein	A0A077K9W3	Ralstonia_phage	5.9e-05	29.7
WP_047653736.1\|4617685_4618393_+	hypothetical protein	A0A077K9W3	Ralstonia_phage	9.7e-08	32.4
WP_032659013.1\|4618396_4619104_+	hypothetical protein	A0A077K9W3	Ralstonia_phage	1.8e-06	31.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP049189

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP049188

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection