CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049225	Lactobacillus iners strain C0059G1 chromosome, complete genome	0 crisprs	DEDDh,DinG,cas3	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

457534 : 484871

Streptococcus_phage(44.44%)

integrase,portal,capsid,terminase

attL 455170:455185|attR 461470:461485

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
455170:455185	attL	NA	NA	NA	NA
WP_006737660.1\|457534_458656_-\|integrase	tyrosine-type recombinase/integrase	Q6SEA7	Lactobacillus_prophage	2.0e-95	48.3
WP_164799111.1\|459214_459715_-	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_164799112.1\|459772_460465_-	helix-turn-helix domain-containing protein	D7RWF2	Brochothrix_phage	8.0e-39	38.2
WP_006735559.1\|460913_461144_+	helix-turn-helix transcriptional regulator	A0A1J0MFH4	Staphylococcus_phage	7.2e-13	53.1
WP_006732601.1\|461243_461381_+	hypothetical protein	NA	NA	NA	NA
WP_006737670.1\|461382_461523_-	Arc family DNA-binding protein	NA	NA	NA	NA
461470:461485	attR	NA	NA	NA	NA
WP_006731472.1\|461604_461748_-	hypothetical protein	NA	NA	NA	NA
WP_006731493.1\|461897_462038_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_160807894.1\|462040_462442_+	Bro-N domain-containing protein	A0A1X9I5P1	Streptococcus_phage	1.1e-13	43.4
WP_164799113.1\|462444_462852_+	Bro-N domain-containing protein	A0A2K9V3K3	Faecalibacterium_phage	1.2e-05	28.1
WP_164799114.1\|462848_463643_+	phage repressor protein/antirepressor Ant	Q6SEF4	Lactobacillus_prophage	9.9e-94	68.3
WP_006731456.1\|463726_464038_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_164799115.1\|464053_464209_+	hypothetical protein	NA	NA	NA	NA
WP_006735993.1\|464742_464937_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_164799277.1\|465079_466054_+	hypothetical protein	Q4ZD94	Staphylococcus_virus	3.0e-39	43.0
WP_164799116.1\|466179_466740_+	hypothetical protein	NA	NA	NA	NA
WP_164799117.1\|466726_467434_+	hypothetical protein	NA	NA	NA	NA
WP_164799118.1\|467430_467889_+	RusA family crossover junction endodeoxyribonuclease	A0A2D1GQ71	Lysinibacillus_phage	2.8e-16	37.1
WP_164799119.1\|467888_468089_+	hypothetical protein	NA	NA	NA	NA
WP_006732599.1\|468110_468593_+	hypothetical protein	Q20DE6	Lactobacillus_phage	4.4e-44	58.1
WP_164799120.1\|469196_469340_+	hypothetical protein	NA	NA	NA	NA
WP_164799121.1\|469552_469873_+	HNH endonuclease	A0A1B1IMY5	Lactococcus_phage	1.9e-40	71.0
WP_164799278.1\|469999_471298_+\|portal	phage portal protein	A0A141E171	Streptococcus_phage	1.0e-143	60.2
WP_164799279.1\|471974_472358_+	MafB	A0A1X9I626	Streptococcus_phage	1.4e-29	51.6
WP_006735983.1\|472326_472527_+	hypothetical protein	M1Q1V7	Streptococcus_phage	7.9e-24	78.5
WP_006729812.1\|472729_473035_+	ImmA/IrrE family metallo-endopeptidase	A0A1X9I661	Streptococcus_phage	6.2e-28	63.7
WP_006735989.1\|473018_473189_-	hypothetical protein	A0A2H4J2N9	uncultured_Caudovirales_phage	5.9e-12	69.1
WP_164799122.1\|473567_474953_+\|terminase	terminase	A0A1P8BMS5	Lactococcus_phage	2.1e-176	62.9
WP_006736002.1\|475100_475553_+	hypothetical protein	A0A126GGH5	Streptococcus_phage	8.1e-08	28.6
WP_006735961.1\|475571_476474_+\|capsid	phage major capsid protein	A0A141E166	Streptococcus_phage	4.9e-121	71.8
WP_006736000.1\|476485_476629_+	hypothetical protein	NA	NA	NA	NA
WP_164799123.1\|476651_477050_+	hypothetical protein	A0A1P8BMQ2	Lactococcus_phage	7.3e-37	67.5
WP_006735971.1\|477068_477401_+	hypothetical protein	Q7Y4I1	Streptococcus_phage	5.2e-20	43.3
WP_164799124.1\|477397_477652_+	hypothetical protein	M1NS01	Streptococcus_phage	4.5e-08	45.6
WP_164799125.1\|477644_477974_+	hypothetical protein	NA	NA	NA	NA
WP_006736001.1\|477989_478604_+	hypothetical protein	M1PKG8	Streptococcus_phage	2.3e-37	45.3
WP_006736017.1\|478596_478884_+	hypothetical protein	NA	NA	NA	NA
WP_035519325.1\|478895_479273_+	hypothetical protein	E8ZDP6	Streptococcus_phage	2.2e-22	48.8
WP_006736008.1\|479265_479796_+	hypothetical protein	A0A1P8BMM1	Lactococcus_phage	2.0e-45	55.3
WP_006735979.1\|480235_482128_+	hypothetical protein	A0A141E161	Streptococcus_phage	1.6e-20	35.2
WP_006735988.1\|482124_482853_+	hypothetical protein	A0A0A8WHP7	Clostridium_phage	2.7e-13	26.8
WP_164799126.1\|482849_484871_+	hypothetical protein	A0A0A8WIC9	Clostridium_phage	2.3e-33	30.9

DBSCAN-SWA_2

598803 : 607100

Cafeteria_roenbergensis_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006736862.1\|598803_599937_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	7.4e-26	31.6
WP_006731694.1\|600126_601965_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	6.4e-19	24.0
WP_009310256.1\|601966_602653_+	class A sortase	NA	NA	NA	NA
WP_009310258.1\|602649_604935_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.6e-72	33.3
WP_164798689.1\|605030_605558_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.3e-22	39.7
WP_102695386.1\|605621_606578_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.3e-108	57.6
WP_006734110.1\|606599_607100_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	6.4e-22	38.2

DBSCAN-SWA_3

664829 : 678465

unidentified_phage(12.5%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006730861.1\|664829_666023_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.0e-41	46.3
WP_006729975.1\|666120_666786_-	hemolysin III family protein	NA	NA	NA	NA
WP_164799154.1\|666912_667764_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.1e-17	41.1
WP_006731940.1\|667772_668000_+	YozE family protein	NA	NA	NA	NA
WP_164799155.1\|668004_669387_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	1.5e-12	28.8
WP_006730880.1\|669600_670440_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_006735970.1\|670436_671189_+	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	1.3e-26	39.3
WP_006731930.1\|671237_672083_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.8e-30	34.1
WP_164799156.1\|672152_674240_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	8.1e-95	35.5
WP_006730884.1\|674289_675603_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_006730858.1\|675605_676529_+	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.0e-25	27.6
WP_006729965.1\|676532_677057_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
WP_009310273.1\|677067_678465_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IEP8	Erwinia_phage	1.8e-29	24.4

DBSCAN-SWA_4

911196 : 931284

Streptococcus_phage(94.12%)

integrase

attL 911139:911156|attR 914988:915005

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
911139:911156	attL	NA	NA	NA	NA
WP_006730188.1\|911196_912504_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-92	47.6
WP_006730099.1\|913100_913574_+	universal stress protein	NA	NA	NA	NA
WP_102215274.1\|913758_914976_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	1.4e-232	99.8
WP_000814511.1\|915057_915261_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
914988:915005	attR	NA	NA	NA	NA
WP_000857133.1\|915721_915952_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|915948_916371_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_164799214.1\|916875_917229_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.5e-57	99.1
WP_000336323.1\|917288_917456_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691736.1\|917574_919494_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
WP_001791010.1\|919509_919626_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|919870_920806_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769868.1\|920802_921804_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|921800_923978_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|923980_926428_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|926411_926918_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_001009056.1\|927506_927728_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000879507.1\|928998_929151_-	hypothetical protein	NA	NA	NA	NA
WP_164799215.1\|929153_930539_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	5.5e-265	99.8
WP_000985015.1\|930567_930954_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_006734372.1\|930969_931284_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	2.6e-53	99.0

DBSCAN-SWA_5

1063877 : 1074854

Bacillus_virus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006730592.1\|1063877_1066106_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.9e-129	41.7
WP_006730630.1\|1066207_1066819_-	glycoside hydrolase family 73 protein	A0A0A7RUS8	Clostridium_phage	6.6e-21	41.1
WP_006732029.1\|1066821_1067433_-	ECF transporter S component	NA	NA	NA	NA
WP_164799232.1\|1067648_1068791_-	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	2.5e-61	32.4
WP_164799233.1\|1068938_1071602_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	8.3e-76	30.4
WP_006735326.1\|1071787_1072624_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	4.9e-67	52.9
WP_006729617.1\|1072626_1074105_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.8e-107	44.1
WP_006729616.1\|1074155_1074854_-	glycosyl transferase	A0A2K9L2U7	Tupanvirus	1.4e-11	27.7

DBSCAN-SWA_6

1107701 : 1120700

Streptococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006729584.1\|1107701_1108286_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.6e-51	51.8
WP_006736301.1\|1108394_1109651_-	AAA domain-containing protein	M1F3L1	Cronobacter_phage	2.9e-07	27.0
WP_006736273.1\|1109666_1111163_-	hypothetical protein	A0A191VYN2	Roseobacter_phage	1.7e-06	23.2
WP_006731198.1\|1111155_1112100_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	7.0e-46	37.1
WP_006729580.1\|1112099_1113134_-	YvcK family protein	A1IMD5	Streptococcus_phage	3.5e-91	52.7
WP_006729579.1\|1113146_1114022_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.0e-06	30.3
WP_006736270.1\|1114073_1116890_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.0e-298	54.9
WP_006733565.1\|1116917_1118915_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_006736272.1\|1118972_1120700_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	5.8e-139	46.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage