CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049226	Lactobacillus iners strain C0011D1 chromosome, complete genome	1 crisprs	cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,DEDDh,DinG	2	17	8	1
NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	3 crisprs	cas14k	2	3	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049226_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049226_1

376963-377972

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
GTATTTCCCGCACATGCGGGGGTGATCC	PILER-CR
GTATTTCCCGCACATGCGGGGGTGATCC	CRISPRCasFinder
GTATTTCCCGCACATGCGGGGGTGATCCT	CRT

16 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP049226_1

>merge|NZ_CP049226|1|376963-377972|PILER-CR,CRISPRCasFinder,CRT
GTATTTCCCGCACATGCGGGGGTGATCCTAATATTTTAATTACTGAATAAGAAAAGAGAAAGTATTTCCCGCACATGCGGGGGTGATCCTGTCAGTTCTTAACTCCCGAATTTCTTCAAGTAGTATTTCCCGCACATGCGGGGGTGATCCTTAAAGCGTGAATATCAAAATAAATTAAGCGAAGTATTTCCCGCACATGCGGGGGTGATCCTTCATCATATCCCTATGTTATGCACTCACAAAAGTATTTCCCGCACATGCGGGGGTGATCCTATGTATTGCGAAAGCACAGTAAACCCACATATGTATTTCCCGCACATGCGGGGGTGATCCTAAAAAAGCCAGTGCACTTTGTGAGTTTGCTGACGTATTTCCCGCACATGCGGGGGTGATCCTGGAGAAGCCAGAAACAGGCGACAGTTCAATTAGTATTTCCCGCACATGCGGGGGTGATCCCTTGAAAGAACAGCAATTATTGTAAATATGAATAGTATTTCCCGCACATGCGGGGGTGATCCTAGGCATAAAATAGTTGTAAAATTGGATAATAGGTATTTCCCGCACATGCGGGGGTGATCCCTAAAGACGGATATAAAAAAGAAATGAAGTATAGTATTTCCCGCACATGCGGGGGTGATCCTCATCATTATCAAAATATGATACTGCTAAAGAAGTATTTCCCGCACATGCGGGGGTGATCCTGTATTGTTGCAGACGTTAACTATAAAAATTTAGGTATTTCCCGCACATGCGGGGGTGATCCCTTGCTGCTCTTGGATAATCTTTTCCTTGATGCGGTATTTCCCGCACATGCGGGGGTGATCCCTAATTGGTGAATTTGGCATTCCTGCTAGAAGAGTATTTCCCGCACATGCGGGGGTGATCCTACCATACCAGAATTTGAAATGCATTTATAGGAGTATTTCCCGCACATGCGGGGGTGATCCTACATCCAACTTACATATTTACTTAACAGGAGTGGTATTTCCCGCACATGCGGGTGACGATTT

>NZ_CP049226|1|1|376963-377909|PILER-CR
GTATTTCCCGCACATGCGGGGGTGATCC	TAATATTTTAATTACTGAATAAGAAAAGAGAAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGTCAGTTCTTAACTCCCGAATTTCTTCAAGTA
GTATTTCCCGCACATGCGGGGGTGATCC	TTAAAGCGTGAATATCAAAATAAATTAAGCGAA
GTATTTCCCGCACATGCGGGGGTGATCC	TTCATCATATCCCTATGTTATGCACTCACAAAA
GTATTTCCCGCACATGCGGGGGTGATCC	TATGTATTGCGAAAGCACAGTAAACCCACATAT
GTATTTCCCGCACATGCGGGGGTGATCC	TAAAAAAGCCAGTGCACTTTGTGAGTTTGCTGAC
GTATTTCCCGCACATGCGGGGGTGATCC	TGGAGAAGCCAGAAACAGGCGACAGTTCAATTA
GTATTTCCCGCACATGCGGGGGTGATCC	CTTGAAAGAACAGCAATTATTGTAAATATGAATA
GTATTTCCCGCACATGCGGGGGTGATCC	TAGGCATAAAATAGTTGTAAAATTGGATAATAG
GTATTTCCCGCACATGCGGGGGTGATCC	CTAAAGACGGATATAAAAAAGAAATGAAGTATA
GTATTTCCCGCACATGCGGGGGTGATCC	TCATCATTATCAAAATATGATACTGCTAAAGAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGTATTGTTGCAGACGTTAACTATAAAAATTTAG
GTATTTCCCGCACATGCGGGGGTGATCC	CTTGCTGCTCTTGGATAATCTTTTCCTTGATGCG
GTATTTCCCGCACATGCGGGGGTGATCC	CTAATTGGTGAATTTGGCATTCCTGCTAGAAGA
GTATTTCCCGCACATGCGGGGGTGATCC	TACCATACCAGAATTTGAAATGCATTTATAGGA
GTATTTCCCGCACATGCGGGGGTGATCC

>NZ_CP049226|1|1|376963-377971|CRISPRCasFinder
GTATTTCCCGCACATGCGGGGGTGATCC	TAATATTTTAATTACTGAATAAGAAAAGAGAAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGTCAGTTCTTAACTCCCGAATTTCTTCAAGTA
GTATTTCCCGCACATGCGGGGGTGATCC	TTAAAGCGTGAATATCAAAATAAATTAAGCGAA
GTATTTCCCGCACATGCGGGGGTGATCC	TTCATCATATCCCTATGTTATGCACTCACAAAA
GTATTTCCCGCACATGCGGGGGTGATCC	TATGTATTGCGAAAGCACAGTAAACCCACATAT
GTATTTCCCGCACATGCGGGGGTGATCC	TAAAAAAGCCAGTGCACTTTGTGAGTTTGCTGAC
GTATTTCCCGCACATGCGGGGGTGATCC	TGGAGAAGCCAGAAACAGGCGACAGTTCAATTA
GTATTTCCCGCACATGCGGGGGTGATCC	CTTGAAAGAACAGCAATTATTGTAAATATGAATA
GTATTTCCCGCACATGCGGGGGTGATCC	TAGGCATAAAATAGTTGTAAAATTGGATAATAG
GTATTTCCCGCACATGCGGGGGTGATCC	CTAAAGACGGATATAAAAAAGAAATGAAGTATA
GTATTTCCCGCACATGCGGGGGTGATCC	TCATCATTATCAAAATATGATACTGCTAAAGAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGTATTGTTGCAGACGTTAACTATAAAAATTTAG
GTATTTCCCGCACATGCGGGGGTGATCC	CTTGCTGCTCTTGGATAATCTTTTCCTTGATGCG
GTATTTCCCGCACATGCGGGGGTGATCC	CTAATTGGTGAATTTGGCATTCCTGCTAGAAGA
GTATTTCCCGCACATGCGGGGGTGATCC	TACCATACCAGAATTTGAAATGCATTTATAGGA
GTATTTCCCGCACATGCGGGGGTGATCC	TACATCCAACTTACATATTTACTTAACAGGAGTG
GTATTTCCCGCACATGCGGGTGACGATT

>NZ_CP049226|1|1|376963-377972|CRT
GTATTTCCCGCACATGCGGGGGTGATCCT	AATATTTTAATTACTGAATAAGAAAAGAGAAA
GTATTTCCCGCACATGCGGGGGTGATCCT	GTCAGTTCTTAACTCCCGAATTTCTTCAAGTA
GTATTTCCCGCACATGCGGGGGTGATCCT	TAAAGCGTGAATATCAAAATAAATTAAGCGAA
GTATTTCCCGCACATGCGGGGGTGATCCT	TCATCATATCCCTATGTTATGCACTCACAAAA
GTATTTCCCGCACATGCGGGGGTGATCCT	ATGTATTGCGAAAGCACAGTAAACCCACATAT
GTATTTCCCGCACATGCGGGGGTGATCCT	AAAAAAGCCAGTGCACTTTGTGAGTTTGCTGAC
GTATTTCCCGCACATGCGGGGGTGATCCT	GGAGAAGCCAGAAACAGGCGACAGTTCAATTA
GTATTTCCCGCACATGCGGGGGTGATCCC	TTGAAAGAACAGCAATTATTGTAAATATGAATA
GTATTTCCCGCACATGCGGGGGTGATCCT	AGGCATAAAATAGTTGTAAAATTGGATAATAG
GTATTTCCCGCACATGCGGGGGTGATCCC	TAAAGACGGATATAAAAAAGAAATGAAGTATA
GTATTTCCCGCACATGCGGGGGTGATCCT	CATCATTATCAAAATATGATACTGCTAAAGAA
GTATTTCCCGCACATGCGGGGGTGATCCT	GTATTGTTGCAGACGTTAACTATAAAAATTTAG
GTATTTCCCGCACATGCGGGGGTGATCCC	TTGCTGCTCTTGGATAATCTTTTCCTTGATGCG
GTATTTCCCGCACATGCGGGGGTGATCCC	TAATTGGTGAATTTGGCATTCCTGCTAGAAGA
GTATTTCCCGCACATGCGGGGGTGATCCT	ACCATACCAGAATTTGAAATGCATTTATAGGA
GTATTTCCCGCACATGCGGGGGTGATCCT	ACATCCAACTTACATATTTACTTAACAGGAGTG
GTATTTCCCGCACATGCGGGTGACGATTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049226.1\|WP_006729005.1\|385757_387131_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP049226.1\|WP_006731157.1\|393723_394587_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP049226.1\|WP_164824898.1\|391477_392467_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
NZ_CP049226.1\|WP_006729007.1\|390220_391420_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP049226.1\|WP_102695512.1\|375069_376008_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP049226.1\|WP_164824897.1\|387460_390055_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
NZ_CP049226.1\|WP_164824888.1\|366039_366819_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP049226.1\|WP_164824890.1\|367546_370300_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP049226.1\|WP_164824894.1\|373667_374405_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187886
NZ_CP049226.1\|WP_141557271.1\|378152_378338_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049226.1\|WP_164824895.1\|376008_376902_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_CP049226.1\|WP_164824899.1\|392629_393724_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP049226.1\|WP_164824892.1\|371984_372572_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP049226.1\|WP_164824889.1\|366818_367427_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|377811
NZ_CP049226.1\|WP_006732689.1\|394588_395407_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP049226.1\|WP_006728837.1\|378466_379111_-\|membrane-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP049226.1\|WP_164824896.1\|379138_380086_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223566
NZ_CP049226.1\|WP_006735522.1\|374413_375073_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP049226.1\|WP_164824891.1\|370286_371975_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP049226.1\|WP_164824893.1\|372574_373651_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153

Protein	Function_ID	Function_description	E-value
NZ_CP049226.1\|WP_006729005.1\|385757_387131_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	6.30429e-150
NZ_CP049226.1\|WP_006731157.1\|393723_394587_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.0198e-65
NZ_CP049226.1\|WP_164824898.1\|391477_392467_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	1.67013e-178
NZ_CP049226.1\|WP_006729007.1\|390220_391420_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP049226.1\|WP_102695512.1\|375069_376008_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.31139e-133
NZ_CP049226.1\|WP_164824897.1\|387460_390055_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
NZ_CP049226.1\|WP_164824888.1\|366039_366819_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.76301e-109
NZ_CP049226.1\|WP_164824890.1\|367546_370300_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	7.33369e-95
NZ_CP049226.1\|WP_164824894.1\|373667_374405_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.00767e-43
NZ_CP049226.1\|WP_164824895.1\|376008_376902_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	1.73246e-44
NZ_CP049226.1\|WP_164824899.1\|392629_393724_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.44518e-131
NZ_CP049226.1\|WP_164824892.1\|371984_372572_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.55212e-30
NZ_CP049226.1\|WP_164824889.1\|366818_367427_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|377811	pfam07314, DUF1461, Protein of unknown function (DUF1461). This family contains a number of hypothetical bacterial proteins of unknown function approximately 200 residues long. These are possibly integral membrane proteins.	2.00564e-30
NZ_CP049226.1\|WP_006732689.1\|394588_395407_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.68914e-62
NZ_CP049226.1\|WP_006728837.1\|378466_379111_-\|membrane-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	8.22673e-66
NZ_CP049226.1\|WP_164824896.1\|379138_380086_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	1.90487e-50
NZ_CP049226.1\|WP_006735522.1\|374413_375073_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.50803e-57
NZ_CP049226.1\|WP_164824891.1\|370286_371975_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	8.70613e-87
NZ_CP049226.1\|WP_164824893.1\|372574_373651_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	2.43603e-152

>NZ_CP049226.1|WP_164824895.1|376008_376902_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MPLTVITLKKSPPSLRGDLTKWMQEISTGVYVGNFNSKIRSELWKRVIENVGMGTATMSYACRNEIGYNFEIHNSNKIPIDFDGIPLVMTHAIENSCSTEYKYGFSNAAKILKAKRYKGNISSIDTNTKPYVIIDLETTGLDYINNNIIEIGAIKIAKNIEEYSCIVKQNITLPNAIKILTGISDAELKNGKDESVAIKELCTFIGDKALVGYNVNFDIKFINEALKRNGQSQLTNKVYDVMKYVKRDKMFLKNYKLDTVLSEYGINIKVPHRAIEDVKIIQLLISKLDGLTNKLKI
>NZ_CP049226.1|WP_102695512.1|375069_376008_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MSKIIGAKKTELNELPRISDRVSFIYVEHAKINRIDSSITVSDYRGVVTIPCAIIGVLMLGPGTDISHRAIEILGDTGTSVIWVGERGVRYYAHGQSLSHSTKLLEKQAKLVSNTKTRLDVARKMYAMRFKNEDVSKLTMQQLRGREGARIRRLYREQATKFKVEWNRRDYKIHDFESSNVVNQALSAANVSLYGVCHSVIVALGMSPGLGFVHTGHDKSFVYDIADLYKAELTIPLAFSLAAEAKDNDDIGQLARLALRDKMLDGRVMQKIVTDLQYLMDISEDEKINADIIELWDDKGENKKYGINYTEE
>NZ_CP049226.1|WP_006735522.1|374413_375073_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRVEIDLYNRKKIRELKHIGCYHGWIEDAFPDERDKPKSARSRKLWRIDNINDKCYLLILSESKPDFKKLEKYGIQHSACTKNYDEFLNSLKEGMRAKFRIKLNTVKSYSNREVYKKRGRVAPVSMDGLNSFFIERTEKNGFFVKDDEFRIIRREEERFEHYAEDKSEETNINLVSATYEGVLTITDLEKFKQTLTKGIGRKKAYGFGFLTIIPIK
>NZ_CP049226.1|WP_164824894.1|373667_374405_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKTILLKLKGPMQSLGTSSHFETRTTDYYPSKSAVIGIIAASFGYKRDNDEKIQKLNELNFAIRIDQPGVLAKDYHIATKYKVNIDKKYKISVAFDRKYVTNRYYMEDAIFVVAISHADDQWIDNIYHALQNPYFTPFMGRRSCPLPADFIITVTNKDALDALQNLEWQAAKWYKRKHQNYCADIYADKDLNLQGIATTRNDRVVSFSQKERKFGPRFETRTSKDFTNGRNDASNSNSLDFYESI
>NZ_CP049226.1|WP_164824893.1|372574_373651_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTNSINQRLFLDIHAIQTVPPSNINRDDTGSPKTAQYGGVTRARVSYQSWKRAIRKYFYDKGDTQNMGIRSCDIVNYIAKIIVEKDKSISVEDAITLVEKTLNAAKLSTKDQKLKALFFISNNQADKFAQACLDKKTDKTELQEILNADTSIDIALFGRMLADDPSLNEDASSQVAHAISTHAIESEFDFYTAVDDLAPEDNAGAGMLGTLEYDSSTLYRYANIALHDFYRQLGDKEEVIAAVKLFVEAFVKSMPTGKINSFANQTLPQAVVVSLRSDRPINLVSAFEEPVKSENGYVDKSIQKLFAEYVKYEKILDKPIFTDYLLLDDTLEVKSIGKSTQNLDELLSDLKESINVNL
>NZ_CP049226.1|WP_164824892.1|371984_372572_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MEGSNVYNVTAKILRKIDQTKDTSSTRALFANIRNSINKSSSNNLDALAFVFNNMPEEYIGFGKELNDYEQAILTAIQMYALHQQSNEKSVLKIEYNEGEKRQNLGDALSTLRGSDNKSIDRRFNAMILSSNFVQLQNHLRQFIKLLKAKSDVKVDYAGVADDLFWFLKNQKDGVKIKWSRSYYKFRKVNDKGEN
>NZ_CP049226.1|WP_164824891.1|370286_371975_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSDYNLIDEPWISVVVDYKGTTKLVGLKEFFEHAHEYIALAGDMPTQDFAVMRFLLAILHTVFSRYDAHGEAYEMIELNDRMQQIEKVDLEDEEDYEDALMETWKDLWNAKKFPDIVAKYLDAWHDRFYLFDDKYPFYQVTKEEIDTSKISKASPSKILGKNINRLISESGNKIALFSPKYDANNNKGLLTYDELTRWLITFQSYTGLSDKVIFGNEKYKASKGWLFDLGGVYLSSDNLYQTLILNLRLINRSNVNYNYSVQKPCWENAPSKLVEKAIRSSCIDNIAELYTTWSRAIYFNKFNMDDVFQMEIVKLPDIKHEDMFLEPMTLWKYNNVGDNKGKFTPRKHQLNKSLWRSFGLMTKFEEAGEVNSKIPKRKPGIIEWLNDIDESIKNQHIKINAISMEDDGNATSWVPINEVEDKLDIGEFIVNDLQKNGWVDRINNIVDRTKDIIEKNYRAFLNDIAKIRGIESGAFTSSSIESMYFKIDKPFRDWLTNINYDDNKDEKEQIWNKELKNLVIRQAKIIIEQASPKDFTGIIENDSVKNIVTAYNNLMSNINKKL
>NZ_CP049226.1|WP_164824890.1|367546_370300_+|CRISPR-associated-helicase-Cas3'
MEKYLWAKKNLVDGVPMWLPLTVHLNDTAEICGLLYEHWLSDGVKDFLEKAIISDVENKEDLLKNLCKFLGAVHDIGKASPIFQTKQSFCGDRELDNLINEKLKQAGFKEVDKYIAERKNNVLHNISGQYFLNKCFKVNLCVANIIGAHHGRPISQEQVVSACESFTSSLYQDDNEKSSLAMFWKEKQRGIFDWAMEACNFSCVEDLPLISQPGQVILSGLLIMADWIASNEKYFPLIPIDTDTVDPDRVEKGFTKWYRDRAETWEPESYCNDIYQKRFGFEPREVQKKVSDIISKIDNPGIVIMEAPMGIGKTETALVAVEELAKKTNRTGIFFGLPTQATSNGIFSRVEDWLKHCEGEKSIRLIHGKAQLNDQFANLPKSRNIHSEDSVGVNEWFAGRKVAILDDFTVGTVDQVLLAALKQKHLMLRHLGFANKVVVIDEVHAYDAYMSVYLYQALMWLGAYGVPVILLSATLPISKRNELLKQYMVGAGYRFKKLDKPKDFNNNENYPLLTYNDGEKINQFSDFSQECGTDYKVIPKAKDESENIVDLINELTTNVGIVGVILNTVKKSQKFAEQCVNAFGEKNVELLHSSFIATDRYKKEQELINTIGKNGKRPKFKIIIGTQVIEQSLDIDFDVLITDLAPMDLLLQRMGRLHRHSDTKRPENLKKPQVYILNCGNYDFDEASTYVYAKYLLFRTEYFLPNKVNLPNDISHLVQLVYSDNALNLSDDSLNKDYTTYQGKYNADIDKKEQQAEVYRLVKPLKNISQEKNLSDWIKNSNHSAELSDVNAYAQVRDSADSVEVIALKKCEGGYEFFDKSGKLDPTDNKTAMEIAKRTIQLPSATYYGIGIDEVIKELEKYYLKHFQDWNQQSWLKGSLAIIFDQNDEFSLLNKKILRYNNKYGLKVVTEDINERL
>NZ_CP049226.1|WP_164824889.1|366818_367427_+|TIGR01906-family-membrane-protein
MKNKLSIVIYNFVAAILLSLWGTILLSWPILLVMMIAQRTNKLIHLSLFGALKNYSQLMSYLINPVSDKLQMSDLQSSLSGLIHFKDCKNLFSIALLLGCIWLFIFLYFEIWKKKKIVSLPHSYTICLLLLPLVVVLLSMGNFTNLFILFHRAMFTNNNWLFNPDTDPIILILTEEFFAACSATFLLIYELYFVRLLIKKGR
>NZ_CP049226.1|WP_164824888.1|366039_366819_+|TIGR01457-family-HAD-type-hydrolase
MSKKYGCYLIDLDGTIYRGEKTIQSGVDFVNRLNEKKIPYLFLTNNTTRTPEMIVAKLASHGVITDVDHVYTPIMATVSYLLEHNPGTDSIPVYIIGQIGLWKGLLAEDRIVLDNNNPKYVIVGMDTDLTYKKICIATNAIRKGAEFIGTNSDHVLPSGDKLLPGNGSQCAMIAVASDQKPFFIGKPSAVIVNYALKKIKKNIEESLIVGDNYETDIMAGINCRMDSLLTLTGVTTKKQLAEEKIQPTYVLNNLDEWQL
>NZ_CP049226.1|WP_141557271.1|378152_378338_+|hypothetical-protein
MGRELMGLASCDDDRKAIINFTIVAAKYFNDQVTVEKINDSLKEYGQAPLTEEEKKFYGVK
>NZ_CP049226.1|WP_006728837.1|378466_379111_-|membrane-protein
MNLLDFILNIDKHLITIVNSCGDWTYLILFLIVFVETGLVVFPFLPGDSLIFATIAMAASPKYHLDLIICYIIFIIAAICGDSINYELGKWSELQSNKFKWFNKLINPQKKKAAEDFFEKHGGITIVIGRFIPIIRTFVPFVSGASKMHYRTFVIYNIVGAFLWVSLFSICGFLFGNIPAVQHHFSLLIIAIIAISILPIIILSIKNKLTKNSK
>NZ_CP049226.1|WP_164824896.1|379138_380086_-|NAD(P)/FAD-dependent-oxidoreductase
MEYYDLAIVGAGPVGLFATKFANLHGLNTITFEALADCGGQINRLFPNKKIKDIPGYNSIIGHQLVDKLKEGINSKIITNYKVQEIIQKDSEIIIDNNYQAKTLLITSGMGAFTPKKLPLPIDSSCEKHIHYFVKNADHFQDKNVAIFGGGDSALDWAMQMADKCKIVIIHRRDQFRGMESTLKFLHQHSNVSFLTPYLPQKIIWQNNQLNILLKKLGTEEMEEIKCDEAVIAFGFKSDNLLLKKWGLNLEAGHVKVNSQMQSNIENIYAAGDACIYDGRVPMMALGFGEAQIAIMSIMNHLFPEKKLTIHLSSH
>NZ_CP049226.1|WP_006729005.1|385757_387131_-|amino-acid-permease
MKQKKSHSSKDISMKRSLTNTHIQLIALGGTIGTGLFLGVGNSIELAGPAVILIYTLVGFFLFLLMRALGELILSDLNKNTYIDFITQYLGKVIGTVTGYLYWFSWLSLGMAELTALGLYFRYWWHDLPLWLPGSITLIILLMINLISAKVFGNMEFSFAIIKILTIVAFVLLVFYLLITNGSTKLYGAISFSNLFKDGGFFAKGANGFFSGFQMVIFSFIGVELIGLTAAEAQDPKKTIVKAINELPVRIILFYVLAILAILLVIPWKQVAINDSPFVQALGATGIKNAACIINFVVISAAISSTNTFIYSGGRLLFSLNYHGQSNFAKCMGQLNKRQLPENALLFSTLLIGIAPIMNLFLENAFHFIAATSTSMFLIIWSIMIWAHIRYRKQTPEQQLHNFRMPLYPYTDYLVLGFFITMIGLLLWVPKDRIPMISALVIFSILILSIKFIKKIK
>NZ_CP049226.1|WP_164824897.1|387460_390055_+|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAKEIASETKKEQIDVQAMIDSYVVQAHVALDKMANFSQEQVDKICEAIAKVGEQNSYLLAKMAVEETGRGIVEDKTIKNMFASENIWNSLRHEKTVGIISEDPERQLIKIAEPVGVIAGVTPVTNPTSTVIFKSMIALKTRNTIIFGFHPQAQKCCVKTAELIREAAIKAGAPDNCIQWIEYPSIEATNALMTHPNIQTILATGGPGMVKAAYSSGKPALGVGPGNGPAYIEKTANYQRAAYDIILSKTFDNGMVCASENSVVIDKDIYDKVKKEFEAWNCYFLNKEEIKKFETTFIDPRRGTVAGPIAGKSAYEIGKLCGVDVPEDTKVIIAEYSGVGKEYPLSAEKLSPVFTMYKVSGADEAFKICKDLLSYGGRGHTVGIHTEDKELIKKFALAMSACRILVNTPAALGGIGDLYNNMLPSMTLGTGSYGANSMSHNISAADLLNIKTVAMRRDNMQWIKVPKKTYFEHNAANYLKHMPDVEKFFIVTDETVAGKYANQITDIISQRLGKKSYEVFQAVKEHPTTDVILDGVHRMNIFKPDAIVALGGGSVMDAAKIMRLFYENPDMTLEDSYQKFIDIRKRVVRFPKTNMVQLVCIPTTSGTGSEVSPFAIIKDTQTGIKHTLCDYSLNPDVAIVDDNFVETLPAKLVANSGMEALAHAMESYVSTMATDFTRGWSMEAIKLIFANLEKSYKGDQAARSKMHNASTLAGMAYANAFLGVGHAIAHTLGSTFNIPSGLSDAITMPYVIKFNAQRPRKLPIRPHYSVFRADKDYAEIARSLGIQGKNDQELVEGLINKFVELAKSINMTLNLKDNGVSEADFNNKVEQLAVEAYGDQNIVTNPSAPLIKQIEQLMKKIYVG
>NZ_CP049226.1|WP_006729007.1|390220_391420_+|acetate-kinase
MKKILAINSGSSSFKYKLFNYPSEEVVAQGQAQRIGLAGATFSLKLADGSKYESEIKIPDHKTAIQLLLTWLPKYNVINDLKEIAGIGHRVVAGGEIFSESALIDKEKLQQIYDLSDYAPLHNPYEADGIRDFMQLLPGVPQVAVFDTSFHHTLDPVHYLYSLPYKYYEKYRARKYGAHGTSVRYVSHRAAELLNKPLNELKMIVCHLGNGASITAIKDGKSYDTSMGFSPVAGITMSTRSGDIDPSVLQYVMKKENISDFNKMINILNNKSGILGISDYSPDMRDIRKKAAAGDVKAKLAKDIFVNRIIKYIGSYYVDMGGLDALVFTAGIGENESLYRQAIVDKLSVLGLKIDEKANSVNGEKVISAVDSKAKILIIPTNEELVIARDVVRLAQINK
>NZ_CP049226.1|WP_164824898.1|391477_392467_-|UDP-glucose-4-epimerase-GalE
MNILVIGGAGYIGSHAVRKLLDSGYHVVVLDNLITGHRKAIDPRAKFYQVDLLNTFLVSKILRNEKIDAVMHFAAYSLVSESVQNPLLYYQNNITGMISLLNAMNDAKVKYLIFSSSAATYGIPEKLPITEEAPLKPINPYGETKMMMEKMMLWADKANNIKSIALRYFNVAGATSDGTIGEDHRTESHLIPNILKCADSNDKIFTIYGNDYQTLDGTNVRDYVEVEDLIDAHILALKHLIKTNLSDVFNLGTTHGYSNLEILECAKRITATDIPYKFGPRRGGDPDSLVADSTKARTILGWQPKHENIDNIIASAWKWHQKHPNGYED
>NZ_CP049226.1|WP_164824899.1|392629_393724_+|ABC-transporter-ATP-binding-protein
MNEDNFIQIKNLKMVYENGYQAISDISFTVKKGELVCLLGPSGCGKTTTLNMVAGLLNPTGGDILVDGKSVLNVAPKDRNIGYVFQNYALYPHMTVLQNVMFPMTVGKNKKSKEEAKQIAERFMRLTHIEEYANQKPGKLSGGQQQRVSIARALVQQPKILLMDEPLSNLDARLRLKIREEIRALVKKVGITTLFVTHDQEEALSIGDKIILFNEGVIQQDAASYEIYLNPANQFVANFIGNPVVDNFNVEVSDGKVKGDGFEIPLSAFDSDRFKKNLTDGVYTLSLRPENVFPVDNQADGFFTCKIDDIELIGRERILKFTINGLGQRSLVKVEANVEPGDEVCFGLNLDRAFIFDNNGERIY
>NZ_CP049226.1|WP_006731157.1|393723_394587_+|sugar-ABC-transporter-permease
MENNQKKAWLFLLPAIISVTIFSIWPIIRAFIISFQGGPLICLNFNGIENYKYIFADTDFWNSLTNTAIYAFMTVPIALAIALALAWFVFSKIRHQSFFEAMFFMPYVTSTIATGIVFRYIFNGKYGLLDFVLKMLHLPAPDWLDDPSMSLISLIIFGIWSSLAFNIVILIGALRNIDPNYYVLADMYGANESEKFWRITIPQLFPTLAFLLTVNLIGAFKVYTQVFALFNGSAGQGNSAITSVFYIYNKFQVANTPGVAMAATVCLFLFILFITCLQRKLMKRVNS
>NZ_CP049226.1|WP_006732689.1|394588_395407_+|carbohydrate-ABC-transporter-permease
MKKIKTVFIYIFVTFFAIITVFPFIYMIFGGLMTYEETTRIPPTFVPGSFKISNYLAVFNQAPFARYFFNTFVTATTTTVVSLFTSILGAFAMANLKFKGKGLIKIILISLLMVPGEAIIFTNYTTIMSMGLINTYIGLVIPFLTSIFYMYYLQSYFKSITPTVYKAAMIDGASDWEYIWRILVPMSKSGLITVALLSFISGWNAFLWPLLVTNESDMRLLNNGLAAFATEAGSQTQLQLAAATLIVLPILIVYFVFRKQIIRGVVNHEFKA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP049226_1	1.14\|377788\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377788-377820	33	NZ_CP049227.1	89293-89325	2	0.939
NZ_CP049226_1	1.30\|377789\|32\|NZ_CP049226\|CRT	377789-377820	32	NZ_CP049227.1	89294-89325	2	0.938

1. spacer 1.14|377788|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to position: 89293-89325, mismatch: 2, identity: 0.939

ctaattggtgaatttggcattcctgctagaaga	CRISPR spacer
ctaattggtgaattgggcatccctgctagaaga	Protospacer
************** *****.************

2. spacer 1.30|377789|32|NZ_CP049226|CRT matches to position: 89294-89325, mismatch: 2, identity: 0.938

taattggtgaatttggcattcctgctagaaga	CRISPR spacer
taattggtgaattgggcatccctgctagaaga	Protospacer
************* *****.************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049226_1	1.16\|377910\|34\|NZ_CP049226\|CRISPRCasFinder	377910-377943	34	NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	73437-73470	1	0.971
NZ_CP049226_1	1.16\|377910\|34\|NZ_CP049226\|CRISPRCasFinder	377910-377943	34	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	82193-82226	1	0.971
NZ_CP049226_1	1.32\|377911\|33\|NZ_CP049226\|CRT	377911-377943	33	NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	73438-73470	1	0.97
NZ_CP049226_1	1.32\|377911\|33\|NZ_CP049226\|CRT	377911-377943	33	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	82194-82226	1	0.97
NZ_CP049226_1	1.14\|377788\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377788-377820	33	NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	80538-80570	2	0.939
NZ_CP049226_1	1.14\|377788\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377788-377820	33	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	89293-89325	2	0.939
NZ_CP049226_1	1.14\|377788\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377788-377820	33	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	3553-3585	2	0.939
NZ_CP049226_1	1.30\|377789\|32\|NZ_CP049226\|CRT	377789-377820	32	NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	80539-80570	2	0.938
NZ_CP049226_1	1.30\|377789\|32\|NZ_CP049226\|CRT	377789-377820	32	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	89294-89325	2	0.938
NZ_CP049226_1	1.30\|377789\|32\|NZ_CP049226\|CRT	377789-377820	32	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	3554-3585	2	0.938
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_AP022823	Enterococcus saigonensis strain VE80 plasmid pVE80-1, complete sequence	49326-49357	6	0.812
NZ_CP049226_1	1.27\|377604\|32\|NZ_CP049226\|CRT	377604-377635	32	KJ473423	Acinetobacter phage vB_AbaP_Acibel007, complete genome	39340-39371	6	0.812
NZ_CP049226_1	1.1\|376991\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	376991-377023	33	NZ_CP018746	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1	33931-33963	7	0.788
NZ_CP049226_1	1.1\|376991\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	376991-377023	33	NZ_CP028865	Borreliella garinii strain 20047 plasmid lp36, complete sequence	3065-3097	7	0.788
NZ_CP049226_1	1.10\|377542\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377542-377574	33	NC_017240	Borreliella afzelii PKo plasmid lp32-10, complete sequence	19129-19161	7	0.788
NZ_CP049226_1	1.11\|377603\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377603-377635	33	KJ473423	Acinetobacter phage vB_AbaP_Acibel007, complete genome	39339-39371	7	0.788
NZ_CP049226_1	1.13\|377726\|34\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377726-377759	34	MH992157	Apis mellifera associated microvirus 3 isolate BeeCNH_SP_2675, complete genome	1407-1440	7	0.794
NZ_CP049226_1	1.13\|377726\|34\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377726-377759	34	MH992174	Apis mellifera associated microvirus 3 isolate IFH_SP_61, complete genome	1407-1440	7	0.794
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP018746	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1	33932-33963	7	0.781
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP028865	Borreliella garinii strain 20047 plasmid lp36, complete sequence	3065-3096	7	0.781
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	MF580775	Streptococcus phage V2, complete genome	7196-7227	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP019926	Borreliella burgdorferi strain PAbe plasmid p_lp56, complete sequence	25432-25463	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP018752	Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed5	4498-4529	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_017428	Borreliella burgdorferi JD1 plasmid JD1 cp32-10, complete sequence	21618-21649	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_017424	Borreliella burgdorferi N40 plasmid N40_cp32-10, complete sequence	21854-21885	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_011720	Borreliella burgdorferi ZS7 plasmid ZS7_cp32-3+10, complete sequence	40272-40303	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP028871	Borreliella garinii strain 20047 plasmid lp32-10, complete sequence	18682-18713	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_000956	Borreliella burgdorferi B31 plasmid lp56, complete sequence	25432-25463	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP019855	Borreliella burgdorferi plasmid lp56, complete sequence	25432-25463	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP019766	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp56, complete sequence	25412-25443	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_017240	Borreliella afzelii PKo plasmid lp32-10, complete sequence	19130-19161	7	0.781
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP018741	Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence	140587-140618	7	0.781
NZ_CP049226_1	1.29\|377727\|33\|NZ_CP049226\|CRT	377727-377759	33	MH992157	Apis mellifera associated microvirus 3 isolate BeeCNH_SP_2675, complete genome	1408-1440	7	0.788
NZ_CP049226_1	1.29\|377727\|33\|NZ_CP049226\|CRT	377727-377759	33	MH992174	Apis mellifera associated microvirus 3 isolate IFH_SP_61, complete genome	1408-1440	7	0.788
NZ_CP049226_1	1.1\|376991\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	376991-377023	33	NZ_CP012102	Bacillus thuringiensis strain HS18-1 plasmid pHS18-3, complete sequence	68911-68943	8	0.758
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP012102	Bacillus thuringiensis strain HS18-1 plasmid pHS18-3, complete sequence	68912-68943	8	0.75
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP028874	Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence	3001-3032	8	0.75
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP042394	Leuconostoc citreum strain CBA3623 plasmid unnamed1, complete sequence	7490-7521	8	0.75
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	233322-233353	8	0.75
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	MN855747	Myoviridae sp. isolate 74, complete genome	3324-3355	8	0.75
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	MH617738	Microviridae sp. isolate ctci904, complete genome	4736-4767	8	0.75
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	NC_021855	Lactococcus phage phi7, complete genome	28971-29002	8	0.75
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	MN552148	Lactococcus phage P1532, complete genome	26073-26104	8	0.75
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	MN694659	Marine virus AFVG_250M322, complete genome	8500-8531	8	0.75
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	KT997856	Uncultured Mediterranean phage uvDeep-CGR2-KM18-C74, complete genome	32943-32974	8	0.75
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	AP013554	Uncultured Mediterranean phage uvMED isolate uvMED-CGR-C28-MedDCM-OCT-S23-C36, * SEQUENCING IN PROGRESS *, 7 ordered pieces	15698-15729	8	0.75
NZ_CP049226_1	1.27\|377604\|32\|NZ_CP049226\|CRT	377604-377635	32	NZ_CP032824	Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence	92048-92079	8	0.75
NZ_CP049226_1	1.27\|377604\|32\|NZ_CP049226\|CRT	377604-377635	32	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	189426-189457	8	0.75
NZ_CP049226_1	1.27\|377604\|32\|NZ_CP049226\|CRT	377604-377635	32	NZ_CP053838	Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence	84924-84955	8	0.75
NZ_CP049226_1	1.1\|376991\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	376991-377023	33	NZ_CP028874	Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence	3000-3032	9	0.727
NZ_CP049226_1	1.1\|376991\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	376991-377023	33	NZ_CP042394	Leuconostoc citreum strain CBA3623 plasmid unnamed1, complete sequence	7489-7521	9	0.727
NZ_CP049226_1	1.2\|377052\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377052-377084	33	MN478377	Bacteriophage Eos, complete genome	82638-82670	9	0.727
NZ_CP049226_1	1.10\|377542\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377542-377574	33	KT997856	Uncultured Mediterranean phage uvDeep-CGR2-KM18-C74, complete genome	32943-32975	9	0.727
NZ_CP049226_1	1.10\|377542\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377542-377574	33	MN694659	Marine virus AFVG_250M322, complete genome	8499-8531	9	0.727
NZ_CP049226_1	1.11\|377603\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377603-377635	33	MF360957	Bacillus virus PBS1, complete genome	182907-182939	9	0.727
NZ_CP049226_1	1.18\|377053\|32\|NZ_CP049226\|CRT	377053-377084	32	MN478377	Bacteriophage Eos, complete genome	82639-82670	9	0.719
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	JQ740790	Lactococcus Phage ASCC284, complete genome	29616-29647	9	0.719
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	KP793104	Lactococcus phage 936 group phage PhiB1127, complete genome	26213-26244	9	0.719
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	KP793109	Lactococcus phage 936 group phage PhiC0139, complete genome	26267-26298	9	0.719
NZ_CP049226_1	1.19\|377114\|32\|NZ_CP049226\|CRT	377114-377145	32	NC_049483	Lactococcus phage CHPC52, complete genome	25341-25372	9	0.719
NZ_CP049226_1	1.20\|377175\|32\|NZ_CP049226\|CRT	377175-377206	32	NZ_AP014826	Geminocystis sp. NIES-3709 plasmid pGM3709_05, complete sequence	25041-25072	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP004872	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB64, complete sequence	15426-15457	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_017205	Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence	22825-22856	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP012101	Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence	246098-246129	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP016596	Bacillus cereus strain K8 plasmid pBCM301, complete sequence	264682-264713	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP011358	Bacillus thuringiensis strain YC-10 plasmid pYC2226, complete sequence	79892-79923	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP015179	Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence	15690-15721	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_018879	Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence	39018-39049	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP015156	Bacillus thuringiensis strain Bc601 plasmid pBTBC6, complete sequence	22044-22075	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP013057	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-2, complete sequence	79069-79100	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP004869	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB67, complete sequence	53042-53073	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP043832	Bacillus sp. BS98 plasmid unnamed2	34320-34351	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	CP024686	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence	201391-201422	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	51779-51810	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP045608	Bacillus cereus strain SB1 plasmid p2, complete sequence	198596-198627	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	CP020758	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence	53253-53284	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NC_020382	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence	44718-44749	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP010093	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence	14758-14789	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP021065	Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence	78728-78759	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	NZ_CP020434	Bacillus sp. FDAARGOS_235 plasmid 1, complete sequence	173851-173882	9	0.719
NZ_CP049226_1	1.26\|377543\|32\|NZ_CP049226\|CRT	377543-377574	32	MN698241	Pelagibacter phage HTVC027P, complete genome	9770-9801	9	0.719
NZ_CP049226_1	1.27\|377604\|32\|NZ_CP049226\|CRT	377604-377635	32	MF360957	Bacillus virus PBS1, complete genome	182907-182938	9	0.719
NZ_CP049226_1	1.4\|377174\|33\|NZ_CP049226\|PILER-CR,CRISPRCasFinder	377174-377206	33	NZ_AP014826	Geminocystis sp. NIES-3709 plasmid pGM3709_05, complete sequence	25040-25072	10	0.697
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	MN692958	Marine virus AFVG_117M8, complete genome	56348-56379	10	0.688
NZ_CP049226_1	1.17\|376992\|32\|NZ_CP049226\|CRT	376992-377023	32	MN694278	Marine virus AFVG_250M229, complete genome	56337-56368	10	0.688

1. spacer 1.16|377910|34|NZ_CP049226|CRISPRCasFinder matches to NZ_CP049229 (Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence) position: , mismatch: 1, identity: 0.971

tacatccaacttacatatttacttaacaggagtg	CRISPR spacer
tacatccaacttacatatttacttaacaggagta	Protospacer
*********************************.

2. spacer 1.16|377910|34|NZ_CP049226|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 1, identity: 0.971

tacatccaacttacatatttacttaacaggagtg	CRISPR spacer
tacatccaacttacatatttacttaacaggagta	Protospacer
*********************************.

3. spacer 1.32|377911|33|NZ_CP049226|CRT matches to NZ_CP049229 (Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence) position: , mismatch: 1, identity: 0.97

acatccaacttacatatttacttaacaggagtg	CRISPR spacer
acatccaacttacatatttacttaacaggagta	Protospacer
********************************.

4. spacer 1.32|377911|33|NZ_CP049226|CRT matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 1, identity: 0.97

acatccaacttacatatttacttaacaggagtg	CRISPR spacer
acatccaacttacatatttacttaacaggagta	Protospacer
********************************.

5. spacer 1.14|377788|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP049229 (Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence) position: , mismatch: 2, identity: 0.939

ctaattggtgaatttggcattcctgctagaaga	CRISPR spacer
ctaattggtgaattgggcatccctgctagaaga	Protospacer
************** *****.************

6. spacer 1.14|377788|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 2, identity: 0.939

ctaattggtgaatttggcattcctgctagaaga	CRISPR spacer
ctaattggtgaattgggcatccctgctagaaga	Protospacer
************** *****.************

7. spacer 1.14|377788|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 2, identity: 0.939

ctaattggtgaatttggcattcctgctagaaga	CRISPR spacer
ctaattggtgaattgggcatccctgctagaaga	Protospacer
************** *****.************

8. spacer 1.30|377789|32|NZ_CP049226|CRT matches to NZ_CP049229 (Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence) position: , mismatch: 2, identity: 0.938

taattggtgaatttggcattcctgctagaaga	CRISPR spacer
taattggtgaattgggcatccctgctagaaga	Protospacer
************* *****.************

9. spacer 1.30|377789|32|NZ_CP049226|CRT matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 2, identity: 0.938

taattggtgaatttggcattcctgctagaaga	CRISPR spacer
taattggtgaattgggcatccctgctagaaga	Protospacer
************* *****.************

10. spacer 1.30|377789|32|NZ_CP049226|CRT matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 2, identity: 0.938

taattggtgaatttggcattcctgctagaaga	CRISPR spacer
taattggtgaattgggcatccctgctagaaga	Protospacer
************* *****.************

11. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_AP022823 (Enterococcus saigonensis strain VE80 plasmid pVE80-1, complete sequence) position: , mismatch: 6, identity: 0.812

aatat-tttaattactgaataagaaaagagaaa	CRISPR spacer
-ctatctttaaatactgaagaagaaaagaaaca	Protospacer
  *** ***** ******* *********.* *

12. spacer 1.27|377604|32|NZ_CP049226|CRT matches to KJ473423 (Acinetobacter phage vB_AbaP_Acibel007, complete genome) position: , mismatch: 6, identity: 0.812

catcattatcaaaatatgatactgctaaagaa	CRISPR spacer
aatacttatcaaaatatgatactggtaaacta	Protospacer
 **  ******************* ****  *

13. spacer 1.1|376991|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP018746 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1) position: , mismatch: 7, identity: 0.788

taatattttaattactgaataagaaaagagaaa	CRISPR spacer
tacaatacaaatttcttaataagaaaagagaaa	Protospacer
**  ** . **** ** ****************

14. spacer 1.1|376991|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP028865 (Borreliella garinii strain 20047 plasmid lp36, complete sequence) position: , mismatch: 7, identity: 0.788

taatattttaattactgaataagaaaagagaaa	CRISPR spacer
tacaatacaaatttcttaataagaaaagagaaa	Protospacer
**  ** . **** ** ****************

15. spacer 1.10|377542|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NC_017240 (Borreliella afzelii PKo plasmid lp32-10, complete sequence) position: , mismatch: 7, identity: 0.788

ctaaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
ctaaagaccaatataaaaaagaaaattttttat-	Protospacer
******** .*********** ****    ***

16. spacer 1.11|377603|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to KJ473423 (Acinetobacter phage vB_AbaP_Acibel007, complete genome) position: , mismatch: 7, identity: 0.788

tcatcattatcaaaatatgatactgctaaagaa	CRISPR spacer
aaatacttatcaaaatatgatactggtaaacta	Protospacer
  **  ******************* ****  *

17. spacer 1.13|377726|34|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to MH992157 (Apis mellifera associated microvirus 3 isolate BeeCNH_SP_2675, complete genome) position: , mismatch: 7, identity: 0.794

cttgctgctcttggataatcttttccttgatgcg	CRISPR spacer
ctatccgctcatggataatcttttcctcgatacc	Protospacer
**  *.**** ****************.***.*

18. spacer 1.13|377726|34|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to MH992174 (Apis mellifera associated microvirus 3 isolate IFH_SP_61, complete genome) position: , mismatch: 7, identity: 0.794

cttgctgctcttggataatcttttccttgatgcg	CRISPR spacer
ctatccgctcatggataatcttttcctcgatacc	Protospacer
**  *.**** ****************.***.*

19. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP018746 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed1) position: , mismatch: 7, identity: 0.781

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
acaatacaaatttcttaataagaaaagagaaa	Protospacer
*  ** . **** ** ****************

20. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP028865 (Borreliella garinii strain 20047 plasmid lp36, complete sequence) position: , mismatch: 7, identity: 0.781

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
acaatacaaatttcttaataagaaaagagaaa	Protospacer
*  ** . **** ** ****************

21. spacer 1.19|377114|32|NZ_CP049226|CRT matches to MF580775 (Streptococcus phage V2, complete genome) position: , mismatch: 7, identity: 0.781

taaagcgtgaatatcaaaataaattaagcgaa--	CRISPR spacer
gaaagcttcaatatcaaaataaat--atcgagtt	Protospacer
 ***** * ***************  * ***.

22. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP019926 (Borreliella burgdorferi strain PAbe plasmid p_lp56, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagactaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

23. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP018752 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid unnamed5) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagaccaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

24. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_017428 (Borreliella burgdorferi JD1 plasmid JD1 cp32-10, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagactaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

25. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_017424 (Borreliella burgdorferi N40 plasmid N40_cp32-10, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagaccaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

26. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_011720 (Borreliella burgdorferi ZS7 plasmid ZS7_cp32-3+10, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagaccaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

27. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP028871 (Borreliella garinii strain 20047 plasmid lp32-10, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagaccaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

28. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_000956 (Borreliella burgdorferi B31 plasmid lp56, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagactaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

29. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP019855 (Borreliella burgdorferi plasmid lp56, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagactaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

30. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP019766 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp56, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagactaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

31. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_017240 (Borreliella afzelii PKo plasmid lp32-10, complete sequence) position: , mismatch: 7, identity: 0.781

taaagacggatataaaaaag-aaatgaagtata	CRISPR spacer
taaagaccaatataaaaaagaaaattttttat-	Protospacer
******* .*********** ****    ***

32. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP018741 (Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence) position: , mismatch: 7, identity: 0.781

--taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
attaaaatt--atataaaaaagaaataaaatata	Protospacer
  ****. .  ***************.**.****

33. spacer 1.29|377727|33|NZ_CP049226|CRT matches to MH992157 (Apis mellifera associated microvirus 3 isolate BeeCNH_SP_2675, complete genome) position: , mismatch: 7, identity: 0.788

ttgctgctcttggataatcttttccttgatgcg	CRISPR spacer
tatccgctcatggataatcttttcctcgatacc	Protospacer
*  *.**** ****************.***.*

34. spacer 1.29|377727|33|NZ_CP049226|CRT matches to MH992174 (Apis mellifera associated microvirus 3 isolate IFH_SP_61, complete genome) position: , mismatch: 7, identity: 0.788

ttgctgctcttggataatcttttccttgatgcg	CRISPR spacer
tatccgctcatggataatcttttcctcgatacc	Protospacer
*  *.**** ****************.***.*

35. spacer 1.1|376991|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP012102 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-3, complete sequence) position: , mismatch: 8, identity: 0.758

taatattttaattactgaataagaaaagagaaa	CRISPR spacer
tcactgataaattacttaataagaatagagaaa	Protospacer
* *.   * ******* ******** *******

36. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP012102 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-3, complete sequence) position: , mismatch: 8, identity: 0.75

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
cactgataaattacttaataagaatagagaaa	Protospacer
 *.   * ******* ******** *******

37. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP028874 (Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
taagtgaaaattactgattaataaaagagaaa	Protospacer
 * .*   ********* *** **********

38. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP042394 (Leuconostoc citreum strain CBA3623 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
tctattttaagtactgtataagaaaatatagt	Protospacer
  ******** ***** ********* * *.

39. spacer 1.17|376992|32|NZ_CP049226|CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

----aatattttaattactgaataagaaaagagaaa	CRISPR spacer
tcgaaaaa----aattacttaaaaagaaaagagaac	Protospacer
    ** *    ******* ** ************

40. spacer 1.19|377114|32|NZ_CP049226|CRT matches to MN855747 (Myoviridae sp. isolate 74, complete genome) position: , mismatch: 8, identity: 0.75

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
tgaaaattgaatatcaaaacaaattaaccggt	Protospacer
*.**.  ************.******* **.

41. spacer 1.19|377114|32|NZ_CP049226|CRT matches to MH617738 (Microviridae sp. isolate ctci904, complete genome) position: , mismatch: 8, identity: 0.75

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
tagaagaagaatatcaaaacaaattaagagac	Protospacer
**.*. . ***********.******** **

42. spacer 1.19|377114|32|NZ_CP049226|CRT matches to NC_021855 (Lactococcus phage phi7, complete genome) position: , mismatch: 8, identity: 0.75

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagttattaga	Protospacer
****** ******** ******* * * ...*

43. spacer 1.19|377114|32|NZ_CP049226|CRT matches to MN552148 (Lactococcus phage P1532, complete genome) position: , mismatch: 8, identity: 0.75

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagcaattaga	Protospacer
****** ******** ******* .** ...*

44. spacer 1.26|377543|32|NZ_CP049226|CRT matches to MN694659 (Marine virus AFVG_250M322, complete genome) position: , mismatch: 8, identity: 0.75

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
ttgtaaaagatgtaaaaaagaaatgaattata	Protospacer
* . .* .***.*************** ****

45. spacer 1.26|377543|32|NZ_CP049226|CRT matches to KT997856 (Uncultured Mediterranean phage uvDeep-CGR2-KM18-C74, complete genome) position: , mismatch: 8, identity: 0.75

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
taaagatggataaaaaaaagaaatcatttcgt	Protospacer
******.***** *********** *  *

46. spacer 1.26|377543|32|NZ_CP049226|CRT matches to AP013554 (Uncultured Mediterranean phage uvMED isolate uvMED-CGR-C28-MedDCM-OCT-S23-C36, *** SEQUENCING IN PROGRESS ***, 7 ordered pieces) position: , mismatch: 8, identity: 0.75

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
taaagatggttataaaaaagaaaacccagata	Protospacer
******.** *************    . ***

47. spacer 1.27|377604|32|NZ_CP049226|CRT matches to NZ_CP032824 (Arcobacter cryaerophilus ATCC 43158 plasmid pACRY43158, complete sequence) position: , mismatch: 8, identity: 0.75

catcattatcaaaatatgatactgctaaagaa	CRISPR spacer
ctcaaatatcaaaaaatgatactgcaaaatca	Protospacer
* . * ******** ********** ***  *

48. spacer 1.27|377604|32|NZ_CP049226|CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 8, identity: 0.75

catcattatcaaaatatgatactgctaaagaa	CRISPR spacer
aatcagtatcaaactatgatactggtttatat	Protospacer
 **** ******* ********** *  * *

49. spacer 1.27|377604|32|NZ_CP049226|CRT matches to NZ_CP053838 (Aliiarcobacter faecis strain CCUG 66484 plasmid pAFAEC, complete sequence) position: , mismatch: 8, identity: 0.75

catcattatcaaaatatgatactgctaaagaa	CRISPR spacer
ctcaaatatcaaaaaatgatactgcaaaatca	Protospacer
* . * ******** ********** ***  *

50. spacer 1.1|376991|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP028874 (Borreliella bavariensis PBi plasmid lp25_cp32-3, complete sequence) position: , mismatch: 9, identity: 0.727

taatattttaattactgaataagaaaagagaaa	CRISPR spacer
gtaagtgaaaattactgattaataaaagagaaa	Protospacer
  * .*   ********* *** **********

51. spacer 1.1|376991|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_CP042394 (Leuconostoc citreum strain CBA3623 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

taatattttaattactgaataagaaaagagaaa	CRISPR spacer
gtctattttaagtactgtataagaaaatatagt	Protospacer
   ******** ***** ********* * *.

52. spacer 1.2|377052|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to MN478377 (Bacteriophage Eos, complete genome) position: , mismatch: 9, identity: 0.727

tgtcagttcttaactcccgaatttcttcaagta-----	CRISPR spacer
tgtcatttcttaactccggaattt-----gatagccat	Protospacer
***** *********** ******     ..**

53. spacer 1.10|377542|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to KT997856 (Uncultured Mediterranean phage uvDeep-CGR2-KM18-C74, complete genome) position: , mismatch: 9, identity: 0.727

ctaaagacggatataaaaaagaaatgaagtata	CRISPR spacer
ataaagatggataaaaaaaagaaatcatttcgt	Protospacer
 ******.***** *********** *  *

54. spacer 1.10|377542|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to MN694659 (Marine virus AFVG_250M322, complete genome) position: , mismatch: 9, identity: 0.727

ctaaagacggatataaaaaagaaatgaagtata	CRISPR spacer
tttgtaaaagatgtaaaaaagaaatgaattata	Protospacer
.* . .* .***.*************** ****

55. spacer 1.11|377603|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 9, identity: 0.727

tcatcattatcaaaatatgatactgctaaagaa	CRISPR spacer
tcatcattatcataaaatgatacttgttgtaat	Protospacer
************ ** ********  * . .*

56. spacer 1.18|377053|32|NZ_CP049226|CRT matches to MN478377 (Bacteriophage Eos, complete genome) position: , mismatch: 9, identity: 0.719

gtcagttcttaactcccgaatttcttcaagta-----	CRISPR spacer
gtcatttcttaactccggaattt-----gatagccat	Protospacer
**** *********** ******     ..**

57. spacer 1.19|377114|32|NZ_CP049226|CRT matches to JQ740790 (Lactococcus Phage ASCC284, complete genome) position: , mismatch: 9, identity: 0.719

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagctattaga	Protospacer
****** ******** ******* . * ...*

58. spacer 1.19|377114|32|NZ_CP049226|CRT matches to KP793104 (Lactococcus phage 936 group phage PhiB1127, complete genome) position: , mismatch: 9, identity: 0.719

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagctattaga	Protospacer
****** ******** ******* . * ...*

59. spacer 1.19|377114|32|NZ_CP049226|CRT matches to KP793109 (Lactococcus phage 936 group phage PhiC0139, complete genome) position: , mismatch: 9, identity: 0.719

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagctattaga	Protospacer
****** ******** ******* . * ...*

60. spacer 1.19|377114|32|NZ_CP049226|CRT matches to NC_049483 (Lactococcus phage CHPC52, complete genome) position: , mismatch: 9, identity: 0.719

taaagcgtgaatatcaaaataaattaagcgaa	CRISPR spacer
taaagcctgaatatccaaataaagctattaga	Protospacer
****** ******** ******* . * ...*

61. spacer 1.20|377175|32|NZ_CP049226|CRT matches to NZ_AP014826 (Geminocystis sp. NIES-3709 plasmid pGM3709_05, complete sequence) position: , mismatch: 9, identity: 0.719

tcatcatatccctatgttatgcactcacaaaa	CRISPR spacer
aaacgctatcgctatgatatgcactcacaagt	Protospacer
  *.  **** ***** *************.

62. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP004872 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB64, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

63. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_017205 (Bacillus thuringiensis serovar chinensis CT-43 plasmid pCT72, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

64. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP012101 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-2, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
atcaaatttatataaaaaagaaattaaatata	Protospacer
   *.*.  *************** **.****

65. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP016596 (Bacillus cereus strain K8 plasmid pBCM301, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
atcaaatttatataaaaaagaaataaaatata	Protospacer
   *.*.  ***************.**.****

66. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP011358 (Bacillus thuringiensis strain YC-10 plasmid pYC2226, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

67. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP015179 (Bacillus thuringiensis serovar alesti strain BGSC 4C1 plasmid pBMB57, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

68. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_018879 (Bacillus thuringiensis Bt407 plasmid BTB_78p, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

69. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP015156 (Bacillus thuringiensis strain Bc601 plasmid pBTBC6, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

70. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP013057 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-2, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

71. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP004869 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB67, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

72. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP043832 (Bacillus sp. BS98 plasmid unnamed2) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
ttataggggatataaaaaagaaatgcattaag	Protospacer
* * .. ****************** * ** .

73. spacer 1.26|377543|32|NZ_CP049226|CRT matches to CP024686 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-2-313K, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
ttataggggatataaaaaagaaatgcattaag	Protospacer
* * .. ****************** * ** .

74. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_018688 (Bacillus thuringiensis MC28 plasmid pMC319, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
atcaaatttatataaaaaagaaataaaatata	Protospacer
   *.*.  ***************.**.****

75. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP045608 (Bacillus cereus strain SB1 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
atcaaatttatataaaaaagaaataaaatata	Protospacer
   *.*.  ***************.**.****

76. spacer 1.26|377543|32|NZ_CP049226|CRT matches to CP020758 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-19, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

77. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NC_020382 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-68, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

78. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP010093 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB71, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

79. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP021065 (Bacillus thuringiensis strain ATCC 10792 plasmid poh4, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
aatttatcaatataaaaaagaactgaaatata	Protospacer
 *   *. .************* ****.****

80. spacer 1.26|377543|32|NZ_CP049226|CRT matches to NZ_CP020434 (Bacillus sp. FDAARGOS_235 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
ttataggggatataaaaaagaaatgcattaag	Protospacer
* * .. ****************** * ** .

81. spacer 1.26|377543|32|NZ_CP049226|CRT matches to MN698241 (Pelagibacter phage HTVC027P, complete genome) position: , mismatch: 9, identity: 0.719

taaagacggatataaaaaagaaatgaagtata	CRISPR spacer
taaagacgattataaaaaagaaaatcctgaca	Protospacer
********. *************      *.*

82. spacer 1.27|377604|32|NZ_CP049226|CRT matches to MF360957 (Bacillus virus PBS1, complete genome) position: , mismatch: 9, identity: 0.719

catcattatcaaaatatgatactgctaaagaa	CRISPR spacer
catcattatcataaaatgatacttgttgtaat	Protospacer
*********** ** ********  * . .*

83. spacer 1.4|377174|33|NZ_CP049226|PILER-CR,CRISPRCasFinder matches to NZ_AP014826 (Geminocystis sp. NIES-3709 plasmid pGM3709_05, complete sequence) position: , mismatch: 10, identity: 0.697

ttcatcatatccctatgttatgcactcacaaaa	CRISPR spacer
aaaacgctatcgctatgatatgcactcacaagt	Protospacer
   *.  **** ***** *************.

84. spacer 1.17|376992|32|NZ_CP049226|CRT matches to MN692958 (Marine virus AFVG_117M8, complete genome) position: , mismatch: 10, identity: 0.688

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
gtatttttaattactgaataaggatagctagg	Protospacer
.   ******************.* **  *..

85. spacer 1.17|376992|32|NZ_CP049226|CRT matches to MN694278 (Marine virus AFVG_250M229, complete genome) position: , mismatch: 10, identity: 0.688

aatattttaattactgaataagaaaagagaaa	CRISPR spacer
gtatttttaattactgaataaggatagctagg	Protospacer
.   ******************.* **  *..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

183046 : 195568

Streptococcus_phage(45.45%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164824846.1\|183046_185461_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	5.6e-305	63.7
WP_164824847.1\|185482_187111_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_006732759.1\|187134_187701_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	5.2e-20	36.2
WP_006730369.1\|188192_189518_-	LexA family transcriptional regulator	D7RWF2	Brochothrix_phage	1.2e-35	41.1
WP_006730350.1\|189544_189862_-	helix-turn-helix transcriptional regulator	A0A141E255	Streptococcus_phage	1.1e-24	59.6
WP_006735923.1\|189904_190624_-	helix-turn-helix domain-containing protein	U3PIS7	Lactobacillus_phage	2.5e-43	44.3
WP_006730335.1\|190697_191366_-	LexA family transcriptional regulator	D7RWL5	Brochothrix_phage	4.1e-40	41.5
WP_006730355.1\|191533_191710_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006730352.1\|191835_191985_+	hypothetical protein	NA	NA	NA	NA
WP_164824848.1\|192144_192324_+	hypothetical protein	NA	NA	NA	NA
WP_164824849.1\|192837_193290_+	hypothetical protein	B8R674	Lactobacillus_phage	3.1e-31	70.2
WP_164825120.1\|193652_194036_+	MafB	A0A1X9I626	Streptococcus_phage	1.2e-28	50.0
WP_006730332.1\|194004_194205_+	hypothetical protein	M1Q1V7	Streptococcus_phage	7.9e-24	80.0
WP_035507533.1\|194750_194957_+	hypothetical protein	Q708N1	Streptococcus_phage	4.5e-22	68.2
WP_006730340.1\|194973_195168_+	hypothetical protein	NA	NA	NA	NA
WP_164824850.1\|195151_195568_+	GTP pyrophosphokinase	A0A141E1X8	Streptococcus_phage	1.6e-18	47.2

DBSCAN-SWA_2

401939 : 450825

Lactobacillus_prophage(30.77%)

terminase,portal,integrase,tRNA,tail,head,capsid

attL 398342:398357|attR 440911:440926

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
398342:398357	attL	NA	NA	NA	NA
WP_164824904.1\|401939_402416_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_006729020.1\|402493_403027_-	exonuclease	M1PFD8	Streptococcus_phage	4.4e-21	36.5
WP_006731171.1\|403140_404055_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_006730689.1\|404109_405216_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.5e-34	43.3
WP_006730672.1\|405202_406015_+	ABC transporter permease	NA	NA	NA	NA
WP_006730696.1\|406011_406812_+	ABC transporter permease	NA	NA	NA	NA
WP_006735851.1\|406808_407882_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006729026.1\|407920_408763_+	TIGR00159 family protein	NA	NA	NA	NA
WP_006729027.1\|408759_409728_+	hypothetical protein	NA	NA	NA	NA
WP_006729028.1\|409751_411104_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_006735496.1\|411294_413106_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	Q76DQ7	Chlorella_virus	3.4e-97	38.2
WP_006734931.1\|413212_414736_+	membrane protein	NA	NA	NA	NA
WP_006738068.1\|414751_415150_+	CrcB family protein	NA	NA	NA	NA
WP_164799103.1\|415149_415500_+	protein CrcB	A0A2H4PQR0	Staphylococcus_phage	6.0e-11	38.8
WP_006737309.1\|415551_416424_-	zinc ABC transporter solute-binding protein	NA	NA	NA	NA
WP_006737342.1\|416698_416995_+	hypothetical protein	NA	NA	NA	NA
WP_164824905.1\|417527_418319_+	Fic family protein	NA	NA	NA	NA
WP_006729034.1\|418501_419233_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_164824906.1\|419304_420540_-	cytosine deaminase	NA	NA	NA	NA
WP_164799105.1\|420551_421811_-	cytosine permease	NA	NA	NA	NA
WP_164824907.1\|421994_422441_-	DUF3021 domain-containing protein	NA	NA	NA	NA
WP_006729038.1\|422437_422869_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_160807902.1\|423019_423511_+	N-acetyltransferase	NA	NA	NA	NA
WP_006732228.1\|430806_431781_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_164824908.1\|431752_432748_+	type II secretion system protein F	NA	NA	NA	NA
WP_006731741.1\|432762_433089_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_080550276.1\|433072_433504_+	type II secretion system protein	NA	NA	NA	NA
WP_006729047.1\|433493_433712_+	hypothetical protein	NA	NA	NA	NA
WP_006735815.1\|433698_434190_+	competence protein ComGF	NA	NA	NA	NA
WP_164824909.1\|434437_435439_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_164824910.1\|435449_436661_+	acetate kinase	NA	NA	NA	NA
WP_006731471.1\|437212_438334_-\|integrase	tyrosine-type recombinase/integrase	Q6SEA7	Lactobacillus_prophage	2.6e-95	48.1
WP_006737543.1\|439480_440050_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_006729801.1\|440743_440932_+	addiction module toxin, HicA family	NA	NA	NA	NA
440911:440926	attR	NA	NA	NA	NA
WP_006729802.1\|440981_441377_+	antitoxin HicB	I3NLB2	Bifidobacterium_phage	1.3e-06	28.2
WP_006730906.1\|441481_441949_+	hypothetical protein	A9D9R6	Lactobacillus_prophage	3.8e-45	59.5
WP_006730944.1\|441938_443168_+\|terminase	PBSX family phage terminase large subunit	A9D9R9	Lactobacillus_prophage	1.6e-138	58.7
WP_006730946.1\|443181_444612_+\|portal	phage portal protein	A0A0A1ER87	Lactobacillus_phage	4.7e-110	45.5
WP_006730975.1\|444604_446197_+\|capsid	minor capsid protein	Q6SED6	Lactobacillus_prophage	2.5e-43	32.6
WP_006730988.1\|446201_446486_+	hypothetical protein	NA	NA	NA	NA
WP_006730954.1\|446519_447011_+	hypothetical protein	NA	NA	NA	NA
WP_006730930.1\|447007_447265_+	hypothetical protein	NA	NA	NA	NA
WP_006730958.1\|447341_447602_+	hypothetical protein	NA	NA	NA	NA
WP_006738119.1\|447717_448323_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_164824911.1\|448336_449209_+	hypothetical protein	A0A0A1ELG8	Lactobacillus_phage	2.4e-80	55.8
WP_164824912.1\|449225_449630_+\|head,tail	phage head-tail connector protein	A0A097BY74	Leuconostoc_phage	5.0e-25	55.7
WP_006730902.1\|449613_449982_+	hypothetical protein	NA	NA	NA	NA
WP_006730949.1\|449981_450362_+	hypothetical protein	NA	NA	NA	NA
WP_006730936.1\|450378_450825_+\|tail	phage major tail protein, TP901-1 family	A0A0A1ELH3	Lactobacillus_phage	1.2e-24	45.0

DBSCAN-SWA_3

557818 : 588974

Streptococcus_phage(35.71%)

integrase,terminase,portal,capsid

attL 554870:554890|attR 575724:575744

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
554870:554890	attL	NA	NA	NA	NA
WP_006731703.1\|557818_559660_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	4.6e-134	47.3
WP_006731699.1\|559728_560862_+	molecular chaperone DnaJ	A0A0P0YNN4	Yellowstone_lake_phycodnavirus	3.7e-25	27.4
WP_164824926.1\|561050_562169_-\|integrase	site-specific integrase	Q6SEA7	Lactobacillus_prophage	5.6e-127	58.7
WP_164824927.1\|562169_562862_-	XRE family transcriptional regulator	D7RWF2	Brochothrix_phage	3.8e-41	40.2
WP_164824928.1\|563014_563224_+	helix-turn-helix transcriptional regulator	D2KRD7	Lactobacillus_phage	5.0e-13	59.7
WP_164824929.1\|563331_563490_+	hypothetical protein	NA	NA	NA	NA
WP_006732601.1\|563507_563645_+	hypothetical protein	NA	NA	NA	NA
WP_006731472.1\|563646_563790_-	hypothetical protein	NA	NA	NA	NA
WP_006731493.1\|563939_564080_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_164824930.1\|564082_564466_+	hypothetical protein	A0A1X9I5P1	Streptococcus_phage	8.4e-14	44.7
WP_164824931.1\|564486_564876_+	hypothetical protein	B6SD57	Bacteriophage	7.7e-07	30.8
WP_164824932.1\|564872_565634_+	phage antirepressor	A0A1Q1PVU2	Staphylococcus_phage	6.2e-77	58.6
WP_164824933.1\|565639_565855_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_164824934.1\|565867_566023_+	hypothetical protein	NA	NA	NA	NA
WP_006735993.1\|566552_566747_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_164824935.1\|566832_567201_+	hypothetical protein	NA	NA	NA	NA
WP_164824936.1\|567187_568069_+	DUF1351 domain-containing protein	Q6SE94	Lactobacillus_prophage	1.0e-51	38.3
WP_006735986.1\|568071_568845_+	hypothetical protein	Q6SEE8	Lactobacillus_prophage	1.3e-93	68.6
WP_164824937.1\|570554_571013_+	RusA family crossover junction endodeoxyribonuclease	A0A2D1GQ71	Lysinibacillus_phage	4.1e-15	44.3
WP_164824938.1\|571013_571214_+	hypothetical protein	NA	NA	NA	NA
WP_164824939.1\|571230_571713_+	hypothetical protein	Q20DE6	Lactobacillus_phage	3.4e-44	58.1
WP_164824940.1\|572295_572442_+	hypothetical protein	NA	NA	NA	NA
WP_006735968.1\|572632_572953_+	HNH endonuclease	A0A1B1IMY5	Lactococcus_phage	4.3e-40	70.1
WP_164824941.1\|573063_574377_+\|portal	phage portal protein	A0A1P8BMI8	Lactococcus_phage	2.7e-144	59.7
WP_164824942.1\|575754_576264_+	N-6 DNA methylase	A0A1S5S8X3	Streptococcus_phage	1.0e-19	34.6
575724:575744	attR	NA	NA	NA	NA
WP_164824943.1\|576244_577273_+	N-6 DNA methylase	A0A1S5S9W3	Streptococcus_phage	4.2e-12	28.6
WP_164824944.1\|577304_577523_+	hypothetical protein	NA	NA	NA	NA
WP_164824945.1\|577673_579059_+\|terminase	terminase	A0A1P8BMS5	Lactococcus_phage	1.5e-174	62.5
WP_006736002.1\|579206_579659_+	hypothetical protein	A0A126GGH5	Streptococcus_phage	8.1e-08	28.6
WP_006735961.1\|579677_580580_+\|capsid	phage major capsid protein	A0A141E166	Streptococcus_phage	4.9e-121	71.8
WP_006736000.1\|580591_580735_+	hypothetical protein	NA	NA	NA	NA
WP_006735953.1\|580757_581156_+	hypothetical protein	A0A1P8BMQ2	Lactococcus_phage	7.3e-37	67.5
WP_006735971.1\|581174_581507_+	hypothetical protein	Q7Y4I1	Streptococcus_phage	5.2e-20	43.3
WP_006735949.1\|581503_581755_+	hypothetical protein	M1NS01	Streptococcus_phage	4.5e-08	45.6
WP_006735958.1\|581747_582077_+	hypothetical protein	NA	NA	NA	NA
WP_006736001.1\|582092_582707_+	hypothetical protein	M1PKG8	Streptococcus_phage	2.3e-37	45.3
WP_164824946.1\|582699_582987_+	hypothetical protein	NA	NA	NA	NA
WP_006735946.1\|583007_583376_+	hypothetical protein	E8ZDP6	Streptococcus_phage	1.0e-21	49.2
WP_006736008.1\|583368_583899_+	hypothetical protein	A0A1P8BMM1	Lactococcus_phage	2.0e-45	55.3
WP_006735979.1\|584338_586231_+	hypothetical protein	A0A141E161	Streptococcus_phage	1.6e-20	35.2
WP_006735988.1\|586227_586956_+	hypothetical protein	A0A0A8WHP7	Clostridium_phage	2.7e-13	26.8
WP_006736018.1\|586952_588974_+	phage minor structural protein, N-terminal domain protein	A0A0A8WIC9	Clostridium_phage	8.6e-33	30.0

DBSCAN-SWA_4

592743 : 601110

Lactobacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164824949.1\|592743_593847_+	glycosyl hydrolase family 25	Q38317	Lactobacillus_phage	4.2e-50	49.5
WP_006731694.1\|594136_595975_+	elongation factor 4	E4ZFJ7	Streptococcus_phage	6.4e-19	24.0
WP_006736527.1\|595976_596663_+	class A sortase	NA	NA	NA	NA
WP_164824950.1\|596659_598945_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.6e-72	33.3
WP_006730727.1\|599041_599569_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.3e-22	39.0
WP_006735980.1\|599631_600588_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.3e-108	57.6
WP_006731693.1\|600609_601110_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	2.4e-21	37.6

DBSCAN-SWA_5

658840 : 672475

unidentified_phage(12.5%)

tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160807844.1\|658840_660034_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.1e-40	45.9
WP_164824958.1\|660130_660796_-	hemolysin III family protein	NA	NA	NA	NA
WP_164799154.1\|660922_661774_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.1e-17	41.1
WP_006731940.1\|661782_662010_+	YozE family protein	NA	NA	NA	NA
WP_164824959.1\|662014_663397_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	1.1e-12	28.8
WP_164824960.1\|663610_664450_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_006731927.1\|664446_665199_+	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	2.0e-27	39.6
WP_006731930.1\|665247_666093_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.8e-30	34.1
WP_102695365.1\|666162_668250_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	1.1e-94	36.1
WP_164823990.1\|668299_669613_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_164798703.1\|669615_670539_+	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	5.1e-25	27.2
WP_006729965.1\|670542_671067_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
WP_009310273.1\|671077_672475_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IEP8	Erwinia_phage	1.8e-29	24.4

DBSCAN-SWA_6

922020 : 942041

Streptococcus_phage(94.74%)

integrase

attL 921963:921980|attR 925812:925829

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
921963:921980	attL	NA	NA	NA	NA
WP_006730188.1\|922020_923328_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-92	47.6
WP_006730099.1\|923924_924398_+	universal stress protein	NA	NA	NA	NA
WP_164825019.1\|924582_925800_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	1.1e-232	99.8
WP_000814511.1\|925881_926085_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
925812:925829	attR	NA	NA	NA	NA
WP_001224508.1\|926550_926781_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.6e-31	88.2
WP_005957428.1\|926777_927203_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	1.4e-70	98.6
WP_001227347.1\|927707_928061_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|928120_928288_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_164825020.1\|928406_930326_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	98.9
WP_001791010.1\|930341_930458_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|930702_931638_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769868.1\|931634_932636_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|932632_934810_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_164825021.1\|934812_937260_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	97.5
WP_025186755.1\|937243_937636_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	1.2e-68	99.2
WP_002368312.1\|937649_938147_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	9.6e-87	94.5
WP_001009056.1\|938263_938485_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|938527_939733_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000879507.1\|939755_939908_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|939910_941296_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|941324_941711_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|941726_942041_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

DBSCAN-SWA_7

1055047 : 1066025

Bacillus_virus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164825043.1\|1055047_1057276_-	DNA helicase PcrA	A7KV33	Bacillus_phage	4.1e-129	41.7
WP_006733924.1\|1057377_1057989_-	glycoside hydrolase family 73 protein	A0A0A7RUS8	Clostridium_phage	1.9e-20	40.4
WP_164825044.1\|1057991_1058603_-	ECF transporter S component	NA	NA	NA	NA
WP_006729620.1\|1058819_1059962_-	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	1.9e-61	32.4
WP_164825045.1\|1060108_1062772_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	1.2e-74	30.1
WP_006729618.1\|1062958_1063795_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	3.7e-67	52.9
WP_006731299.1\|1063797_1065276_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	2.9e-107	44.3
WP_006729616.1\|1065326_1066025_-	glycosyl transferase	A0A2K9L2U7	Tupanvirus	1.4e-11	27.7

DBSCAN-SWA_8

1100500 : 1113499

Streptococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006729584.1\|1100500_1101085_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.6e-51	51.8
WP_164825050.1\|1101193_1102450_-	AAA domain-containing protein	M1F3L1	Cronobacter_phage	5.9e-08	27.6
WP_006734834.1\|1102465_1103962_-	hypothetical protein	A0A191VYN2	Roseobacter_phage	1.7e-06	23.2
WP_006731198.1\|1103954_1104899_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	7.0e-46	37.1
WP_006729580.1\|1104898_1105933_-	YvcK family protein	A1IMD5	Streptococcus_phage	3.5e-91	52.7
WP_006729579.1\|1105945_1106821_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.0e-06	30.3
WP_164825051.1\|1106872_1109689_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.9e-297	54.9
WP_164825052.1\|1109716_1111714_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_006737223.1\|1111771_1113499_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	5.8e-139	45.8

Anti-CRISPR protein detection

Acr_ID: NZ_CP049226.1|WP_164824934.1|565867_566023_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP049226.1|WP_164824934.1|565867_566023_+|hypothetical-protein

565867_566023_+

51 aa aa

557818-588974

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP049227_2	Orphan	2.1\|9544\|53\|NZ_CP049227\|CRISPRCasFinder	9544-9596	53	577606-577554	2

1. spacer 2.1|9544|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049226 position: 577606-577554, mismatch: 2

tttttatttattttggctatttatagccatttgagttaattgggaagttttat	CRISPR spacer
tttttatttattttggctatttatagccatttgagttgattaggaagttttat	Protospacer
*************************************.***.***********

2. NZ_CP049227

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049227_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049227_1

1730-1845

Orphan

Consensus_repeat	Method
ATATGGTTATATATCACATGTATTAATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049227_1

>merge|NZ_CP049227|1|1730-1845|CRISPRCasFinder
ATATGGTTATATATCACATGTATTAATGTATTTTATGCATCCTTATATGGTTATATATCGCATGTATTAATGTATTTTATGCATCCCTATATGGTTATATATCGCATGTATTAATG

>NZ_CP049227|1|1|1730-1845|CRISPRCasFinder
ATATGGTTATATATCACATGTATTAATG	TATTTTATGCATCCTTATATGGTTATATATCGCATGTATTAATGTATTTTATGCATCCCT
ATATGGTTATATATCGCATGTATTAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049227.1\|WP_164798927.1\|422_1058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825136.1\|1928_2684_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_102215581.1\|4945_5197_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|366631
NZ_CP049227.1\|WP_164825137.1\|2762_4394_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|370635
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	unknown	unknown	gnl\|CDD\|226036
NZ_CP049227.1\|WP_164825135.1\|1057_1699_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825140.1\|8258_9440_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NZ_CP049227.1\|WP_164825134.1\|52_409_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP049227.1\|WP_164825144.1\|12325_12784_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825138.1\|4492_4930_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	6.26883e-11
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	5.47565e-18
NZ_CP049227.1\|WP_164825134.1\|52_409_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.09838e-08
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	gnl\|CDD\|366631	pfam01420, Methylase_S, Type I restriction modification DNA specificity domain. This domain is also known as the target recognition domain (TRD). Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity subunit (this family), two modification (M) subunits and two restriction (R) subunits.	1.29412e-09
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.91663e-10
NZ_CP049227.1\|WP_164825137.1\|2762_4394_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|370635	pfam09726, Macoilin, Macoilin family. The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.	1.86898e-08

>NZ_CP049227.1|WP_164825135.1|1057_1699_+|hypothetical-protein
MNFVKKIFLTVISIGTIIGLALVIITSHCNKAYSSKLSELKTERTQQHSQLKVMREKIKNNLIANAKSSNSKRIRNSVQYLELTKNIQEKAKELCQALFNYDNEKEYLFRYKKVSDILAKSALSNQAIFPSGKYAAKLEGQKLKARLNDVNVFIGTTDNKQNIPLLMRVNYSEFSNNKVIKIDDEALEVIFSTQKDKFISIKSIGKFPVNNSN
>NZ_CP049227.1|WP_164798927.1|422_1058_+|hypothetical-protein
MRNIKEIKYKSTLIYILVTSVLLLMFITTLLVAYHNYQSIEHTKRCISDVELDIKKINKIKLKQPHTIIFKSPLSMDKLDLEKAESRAIAKIKQGMTLTFGSLKTKKDFADKKGEIAKLMGSKFANFWVIPNHDTQYVKNDFTNCYFANSNDIYHMKCVAYAQYQVKEAGQSVPCSIMLLIDYDLSEQKVNNFDIVTFLTNDVLDYTGSNL
>NZ_CP049227.1|WP_164825134.1|52_409_+|M23-family-metallopeptidase
MMGQYVLAIHGGTVYKIGHEGYTQADLGWYVCVKSNDGYYEIYQEFAFADSDRRAIKVKVGDVVKTGQPIGILSSKFHNVTHVHIGVTKKEIMAAERHAFLDDGTWKNWIEFVKKSNK
>NZ_CP049227.1|WP_164825136.1|1928_2684_+|hypothetical-protein
MFILIFTTAGIVLSLTYINRSSKKMLVTTFGFSSQIYLGFLGIIMHEFSHFIVAIFFGHKIKQVKFIILPKQAHTDGNLGYVDHTWNNHSLWQSLGNLFIGTAPIWGCTTFLYVIIQDMLPSLYDYFSNVQVAILSKQWSNIFNFPAICGGTLHDYIITIIAIYLICNVTIGGFDLSNADLMSSWPAFLALCTVILMICITSYLVGLSTLVDTILLTMSLNFVIVMSLSLIFSILINILIRYFCFFIKLQK
>NZ_CP049227.1|WP_164825137.1|2762_4394_+|LPXTG-cell-wall-anchor-domain-containing-protein
MSISKKIELASGIALVAGAGAGMTVPSLAITAHADTAHNQDTTVNPSVGDNQTGDVQVTSDKDAYNDVQGDEKQDTNDAKQHSSKAFEYMTPEEGASSWKHKEDWQTEPGTDNTQTDWAIAENANGKTASDTSAKVYGDTSEARFNPGDHDNRKMTSLKWTDRDADGDGEEDKVEGPINPYLGNYFYNGFYPGYYQDGGSVVVANNNNNNNNNNNNNNSSNNGNNANNLAGANDYDDGDYYDDGYDDGYDDGYYDGYDDDADDYVDGVDVVHGHRHVDNRHQKIVNGSQVGAGNNAQKTDNKTTQIGQNMAGNDIKATATDGRHIVINGGNASGLPGDGNGTYVIRTADGESIVVSNNNNNNNNNNSGNNGNNNNGSNLANNVVHHHHGHIIRHYVTKPLSPSTINVISKAENIASGNSKGGTNTATNTSMPNTVSKSGMNGSGNSTTVSNSGANSSTPNTVSKSNINGSGNSTTVSNSVANNAMPNTISNSGNVVTADNNGTNVASVALPQTGTDDHDAALATMGGVIMTSLAALGISKKLI
>NZ_CP049227.1|WP_164825138.1|4492_4930_+|hypothetical-protein
MNQTTFWIYLNNYSNIICGIFNILNILWMLEMCINGYIQRKDINFGMDEVNWTIDLKICTLLSLMGMGALYLPAISSGFGFEVYVIAVYIVVIQALMMKSYRKKLMKKISEAWFLTSTKVSMLISILTAISILTYAISSIVVFDY
>NZ_CP049227.1|WP_102215581.1|4945_5197_+|hypothetical-protein
MREKQNIDVVAAYDAYKNDIYEMLLALKITNKVAIALMKRDEQRINEAFGSAKIPIITPQVVARMMVENYWNDLGNLYGQKKI
>NZ_CP049227.1|WP_164825139.1|5422_8254_+|TraM-recognition-domain-containing-protein
MFEYIRMQVEKKYNSFSSLLSNQDLKTNLLLFDTIRTFCWLADFVVWFLCFMQIFAPMLNLNFQIINIFCWLVVAICLIGAVNVNWFMILFTTRRLDIDQDDRADVMWKILQSSFWQISFICGSAIAIPLCMTVFPFIQYLRLHPVIPGWTPQMTDMVAGSPFILRALLFGVPIIFTFYLHVRFQYLASVFEQRIKDWMKVYEFKYKCMHDTLTGKDMADVKKDKKEPSIILGDSLETGDAIIQSPIARRQNSIVTGPIGAGKTSAWFLNQILQDINHMIRFMRDYATVSQDPDWNKPFGMQQNYLCGFAVIETTGDLCNTVLRYALKKGIPREKIIYYNPEDPNTPSFSLLNGPVETATQTLTDIMSGLKKNANDFFSMQERTHLTQYIFLLKESSIIDSKPADFGELMKMYNDVYVVIDKREKLRTYCKILENQIDKLNRQKCDNDQAQHKIDVAIEEIQDKLAVNRETLAWFDSNIVSLQFKTGVKLLQQEGPHKGEPVYVDKNMEFIGGLISQLTELSKKMGLRRVLFRDKVDFSLDDAMKNGCIILCNTAKDMLGETSARMLGQIYSLAFQGATFRRTPNVDPMFPIYQDEFPDYLYDNFTDFAAQARKYNVPLNIGAQSPAQLSKKFGPDFLRTIFSVMLTRATFGDMGYDDALVLSRLFGTHKEAIESINEQDIDLAADCARNRKMISSRLQEVPNISPEEIMGLEKFTMAVRLPGEHRSDVFDRVRVRRITDEMVENDPENFDINGKDKKAYEDMKALEVHTNKDFDNIDKQIIQKIKDGTIKLSTSNTVKSPAKFDRVVKNSSSNAVTDLPQSMDDFEQVFSNQEKEAAFNAVDDSVTKSGNCGNNRFNNNISIANDISSAKDLPSDNKTVAESSKVTKANKKPSLDDSIKTMHNIPVSKLFSQDSLREYDQEEPFDGKDPFNSQPGMDDNESR
>NZ_CP049227.1|WP_164825140.1|8258_9440_+|hypothetical-protein
MSIKKLILEPTVLNIWKYRPLSQCIKKDSTSGVLVINDIYQADAVKDTGGILINDKGPDLLFNIQNLSTKNLQLLVDSYFEVPLPNPCVFTKKTILFFLQLLVLNAKKKKTSIYEELKNWYQLSDTEISKYMDALNIDINSEIKNIFSKNPQYVEAIVSFLWKCHGFESHHEINLSQDKNILVIPVSLLTKYYYLVVLHYFYKQNWNIFFDTDVPFSLVQEFVVQGSSADIYACRYSNDPLIATLASQADEMWSTAQGDPTTFFNWVGKKAPEALKNYSLTNMKRLLSGLNYSSFLSKYFILSDKTIMLARLQENSEWEAKPFDLDFLISQTIDKGNKDIETLSKKIESLSAKVDQLSDICNKATLTDSEGLNKQFDEMLKKQGNNDNFIDFM
>NZ_CP049227.1|WP_164825141.1|9629_9815_-|IS3-family-transposase
MFRKGHCHDNAVMENFFGLFKQEIYYGVTYYSYDYLKLEIKRYIKYYNEQRIKEKLNTFYQ
>NZ_CP049227.1|WP_164825142.1|9979_11770_+|N-6-DNA-methylase
MSLRTEDQVRDYAKLVLGFDETEENIEQGTGQITTFNQLGFKGYSDKPDGWYLPKNMNDVAIILETKSEKRDISKQIFIDELMKNIDIISSKYKKTVGILYNGKEIAIYKNKELIRVANKLQHKQYYIDLFKENYIDKNKIFTLTKRINDLLHFKFGIKNLYHRMIFTASALVVERFGGNLEAIKDNGYEPFRNKIYDTLAKSLQDHRRQNLKIDILLEVYSEIKMNIVENQDDINKFIDCIIEIAESINSDNWNGEDVMGIFFNEFNRYKKKSESGQVFTPEHITSFMYDLLEITYNDRLLDATCGSGAFLVKAMANMIKEVGGVNTKEAEDIKQNKLYGIEFDREIFALACANMLIHKDGKTNLEQYDTREKEACKWIKSKNITKVLMNPPYERKYGCKKIVTNVLDNVPVGTKCAFILPDKKLEKDKMQSLLKRHTLDMIIKLPEKLFDEGVTTSVFVFETGKPQKDKKIFACYMEDDGLERVKNQGRHDIKNKWKEIEKYWLEVVRTKVDTKYNTHQWIDSKENLSYQKPQKPFEIYEEDFKKTIIDFILFEEKIDVKEFNEKLLNQVLYKSEYKDGKLMLDVGEENEENKD
>NZ_CP049227.1|WP_164825143.1|11750_12272_+|N-6-DNA-methylase
MKKIKIDDWKPFEIEKLFTVKRPKSRSVKKYNEGEIPFVSSGNYNNGVDSYREPIDDEDLDKGNCITVSPVDGSTFYQPQDFLGRGGGGSSIMLLYNDNLNKFNGLFIASVIRESLKIKYQYNDMGSSDSIKKENILLPALDDKTPDWNFMEESMKRLETRERERVQAILQAI
>NZ_CP049227.1|WP_164825144.1|12325_12784_+|hypothetical-protein
MDFFSPITVKNKVMIYDIKNFGTTPVYASDSSYKNNIGYIDDEPEFYVNDEQSMYVIFGDHTKSMRIIETNFSVTDNVKVLSPKIKSKNSLFFVMTSWLANIPDLGYSRHWSIAKKTKIKLPVKSDNSPDWEYMERYIENLKLKCNIANYNI

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Crispr_ID: NZ_CP049227_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049227_2

9521-9619

Orphan

Consensus_repeat	Method
TTCACACGATTAACTCACGATTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049227_2

>merge|NZ_CP049227|2|9521-9619|CRISPRCasFinder
TTCACACGATTAACTCACGATTATTTTTATTTATTTTGGCTATTTATAGCCATTTGAGTTAATTGGGAAGTTTTATTTCACACGATTAACTCACGATTA

>NZ_CP049227|2|2|9521-9619|CRISPRCasFinder
TTCACACGATTAACTCACGATTA	TTTTTATTTATTTTGGCTATTTATAGCCATTTGAGTTAATTGGGAAGTTTTAT
TTCACACGATTAACTCACGATTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049227.1\|WP_006734626.1\|19513_21013_+\|ATPase-AAA	unknown	unknown	gnl\|CDD\|225420
NZ_CP049227.1\|WP_164825145.1\|13012_14680_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP049227.1\|WP_164798927.1\|422_1058_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825136.1\|1928_2684_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_145999009.1\|15655_16180_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_102215581.1\|4945_5197_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825148.1\|17417_19004_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP049227.1\|WP_164825146.1\|14874_15690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|366631
NZ_CP049227.1\|WP_164825137.1\|2762_4394_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|370635
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	unknown	unknown	gnl\|CDD\|226036
NZ_CP049227.1\|WP_164825140.1\|8258_9440_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825135.1\|1057_1699_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NZ_CP049227.1\|WP_164825134.1\|52_409_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP049227.1\|WP_164825144.1\|12325_12784_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825138.1\|4492_4930_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825147.1\|16202_17018_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	6.26883e-11
NZ_CP049227.1\|WP_164825145.1\|13012_14680_-\|hypothetical-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.81974e-05
NZ_CP049227.1\|WP_006734626.1\|19513_21013_+\|ATPase-AAA	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	9.16073e-36
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	5.47565e-18
NZ_CP049227.1\|WP_164825134.1\|52_409_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.09838e-08
NZ_CP049227.1\|WP_164825148.1\|17417_19004_+\|hypothetical-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	7.77663e-05
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	gnl\|CDD\|366631	pfam01420, Methylase_S, Type I restriction modification DNA specificity domain. This domain is also known as the target recognition domain (TRD). Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity subunit (this family), two modification (M) subunits and two restriction (R) subunits.	1.29412e-09
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.91663e-10
NZ_CP049227.1\|WP_164825137.1\|2762_4394_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|370635	pfam09726, Macoilin, Macoilin family. The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.	1.86898e-08

>NZ_CP049227.1|WP_164825140.1|8258_9440_+|hypothetical-protein
MSIKKLILEPTVLNIWKYRPLSQCIKKDSTSGVLVINDIYQADAVKDTGGILINDKGPDLLFNIQNLSTKNLQLLVDSYFEVPLPNPCVFTKKTILFFLQLLVLNAKKKKTSIYEELKNWYQLSDTEISKYMDALNIDINSEIKNIFSKNPQYVEAIVSFLWKCHGFESHHEINLSQDKNILVIPVSLLTKYYYLVVLHYFYKQNWNIFFDTDVPFSLVQEFVVQGSSADIYACRYSNDPLIATLASQADEMWSTAQGDPTTFFNWVGKKAPEALKNYSLTNMKRLLSGLNYSSFLSKYFILSDKTIMLARLQENSEWEAKPFDLDFLISQTIDKGNKDIETLSKKIESLSAKVDQLSDICNKATLTDSEGLNKQFDEMLKKQGNNDNFIDFM
>NZ_CP049227.1|WP_164825139.1|5422_8254_+|TraM-recognition-domain-containing-protein
MFEYIRMQVEKKYNSFSSLLSNQDLKTNLLLFDTIRTFCWLADFVVWFLCFMQIFAPMLNLNFQIINIFCWLVVAICLIGAVNVNWFMILFTTRRLDIDQDDRADVMWKILQSSFWQISFICGSAIAIPLCMTVFPFIQYLRLHPVIPGWTPQMTDMVAGSPFILRALLFGVPIIFTFYLHVRFQYLASVFEQRIKDWMKVYEFKYKCMHDTLTGKDMADVKKDKKEPSIILGDSLETGDAIIQSPIARRQNSIVTGPIGAGKTSAWFLNQILQDINHMIRFMRDYATVSQDPDWNKPFGMQQNYLCGFAVIETTGDLCNTVLRYALKKGIPREKIIYYNPEDPNTPSFSLLNGPVETATQTLTDIMSGLKKNANDFFSMQERTHLTQYIFLLKESSIIDSKPADFGELMKMYNDVYVVIDKREKLRTYCKILENQIDKLNRQKCDNDQAQHKIDVAIEEIQDKLAVNRETLAWFDSNIVSLQFKTGVKLLQQEGPHKGEPVYVDKNMEFIGGLISQLTELSKKMGLRRVLFRDKVDFSLDDAMKNGCIILCNTAKDMLGETSARMLGQIYSLAFQGATFRRTPNVDPMFPIYQDEFPDYLYDNFTDFAAQARKYNVPLNIGAQSPAQLSKKFGPDFLRTIFSVMLTRATFGDMGYDDALVLSRLFGTHKEAIESINEQDIDLAADCARNRKMISSRLQEVPNISPEEIMGLEKFTMAVRLPGEHRSDVFDRVRVRRITDEMVENDPENFDINGKDKKAYEDMKALEVHTNKDFDNIDKQIIQKIKDGTIKLSTSNTVKSPAKFDRVVKNSSSNAVTDLPQSMDDFEQVFSNQEKEAAFNAVDDSVTKSGNCGNNRFNNNISIANDISSAKDLPSDNKTVAESSKVTKANKKPSLDDSIKTMHNIPVSKLFSQDSLREYDQEEPFDGKDPFNSQPGMDDNESR
>NZ_CP049227.1|WP_102215581.1|4945_5197_+|hypothetical-protein
MREKQNIDVVAAYDAYKNDIYEMLLALKITNKVAIALMKRDEQRINEAFGSAKIPIITPQVVARMMVENYWNDLGNLYGQKKI
>NZ_CP049227.1|WP_164825138.1|4492_4930_+|hypothetical-protein
MNQTTFWIYLNNYSNIICGIFNILNILWMLEMCINGYIQRKDINFGMDEVNWTIDLKICTLLSLMGMGALYLPAISSGFGFEVYVIAVYIVVIQALMMKSYRKKLMKKISEAWFLTSTKVSMLISILTAISILTYAISSIVVFDY
>NZ_CP049227.1|WP_164825137.1|2762_4394_+|LPXTG-cell-wall-anchor-domain-containing-protein
MSISKKIELASGIALVAGAGAGMTVPSLAITAHADTAHNQDTTVNPSVGDNQTGDVQVTSDKDAYNDVQGDEKQDTNDAKQHSSKAFEYMTPEEGASSWKHKEDWQTEPGTDNTQTDWAIAENANGKTASDTSAKVYGDTSEARFNPGDHDNRKMTSLKWTDRDADGDGEEDKVEGPINPYLGNYFYNGFYPGYYQDGGSVVVANNNNNNNNNNNNNNSSNNGNNANNLAGANDYDDGDYYDDGYDDGYDDGYYDGYDDDADDYVDGVDVVHGHRHVDNRHQKIVNGSQVGAGNNAQKTDNKTTQIGQNMAGNDIKATATDGRHIVINGGNASGLPGDGNGTYVIRTADGESIVVSNNNNNNNNNNSGNNGNNNNGSNLANNVVHHHHGHIIRHYVTKPLSPSTINVISKAENIASGNSKGGTNTATNTSMPNTVSKSGMNGSGNSTTVSNSGANSSTPNTVSKSNINGSGNSTTVSNSVANNAMPNTISNSGNVVTADNNGTNVASVALPQTGTDDHDAALATMGGVIMTSLAALGISKKLI
>NZ_CP049227.1|WP_164825136.1|1928_2684_+|hypothetical-protein
MFILIFTTAGIVLSLTYINRSSKKMLVTTFGFSSQIYLGFLGIIMHEFSHFIVAIFFGHKIKQVKFIILPKQAHTDGNLGYVDHTWNNHSLWQSLGNLFIGTAPIWGCTTFLYVIIQDMLPSLYDYFSNVQVAILSKQWSNIFNFPAICGGTLHDYIITIIAIYLICNVTIGGFDLSNADLMSSWPAFLALCTVILMICITSYLVGLSTLVDTILLTMSLNFVIVMSLSLIFSILINILIRYFCFFIKLQK
>NZ_CP049227.1|WP_164825135.1|1057_1699_+|hypothetical-protein
MNFVKKIFLTVISIGTIIGLALVIITSHCNKAYSSKLSELKTERTQQHSQLKVMREKIKNNLIANAKSSNSKRIRNSVQYLELTKNIQEKAKELCQALFNYDNEKEYLFRYKKVSDILAKSALSNQAIFPSGKYAAKLEGQKLKARLNDVNVFIGTTDNKQNIPLLMRVNYSEFSNNKVIKIDDEALEVIFSTQKDKFISIKSIGKFPVNNSN
>NZ_CP049227.1|WP_164798927.1|422_1058_+|hypothetical-protein
MRNIKEIKYKSTLIYILVTSVLLLMFITTLLVAYHNYQSIEHTKRCISDVELDIKKINKIKLKQPHTIIFKSPLSMDKLDLEKAESRAIAKIKQGMTLTFGSLKTKKDFADKKGEIAKLMGSKFANFWVIPNHDTQYVKNDFTNCYFANSNDIYHMKCVAYAQYQVKEAGQSVPCSIMLLIDYDLSEQKVNNFDIVTFLTNDVLDYTGSNL
>NZ_CP049227.1|WP_164825134.1|52_409_+|M23-family-metallopeptidase
MMGQYVLAIHGGTVYKIGHEGYTQADLGWYVCVKSNDGYYEIYQEFAFADSDRRAIKVKVGDVVKTGQPIGILSSKFHNVTHVHIGVTKKEIMAAERHAFLDDGTWKNWIEFVKKSNK
>NZ_CP049227.1|WP_164825141.1|9629_9815_-|IS3-family-transposase
MFRKGHCHDNAVMENFFGLFKQEIYYGVTYYSYDYLKLEIKRYIKYYNEQRIKEKLNTFYQ
>NZ_CP049227.1|WP_164825142.1|9979_11770_+|N-6-DNA-methylase
MSLRTEDQVRDYAKLVLGFDETEENIEQGTGQITTFNQLGFKGYSDKPDGWYLPKNMNDVAIILETKSEKRDISKQIFIDELMKNIDIISSKYKKTVGILYNGKEIAIYKNKELIRVANKLQHKQYYIDLFKENYIDKNKIFTLTKRINDLLHFKFGIKNLYHRMIFTASALVVERFGGNLEAIKDNGYEPFRNKIYDTLAKSLQDHRRQNLKIDILLEVYSEIKMNIVENQDDINKFIDCIIEIAESINSDNWNGEDVMGIFFNEFNRYKKKSESGQVFTPEHITSFMYDLLEITYNDRLLDATCGSGAFLVKAMANMIKEVGGVNTKEAEDIKQNKLYGIEFDREIFALACANMLIHKDGKTNLEQYDTREKEACKWIKSKNITKVLMNPPYERKYGCKKIVTNVLDNVPVGTKCAFILPDKKLEKDKMQSLLKRHTLDMIIKLPEKLFDEGVTTSVFVFETGKPQKDKKIFACYMEDDGLERVKNQGRHDIKNKWKEIEKYWLEVVRTKVDTKYNTHQWIDSKENLSYQKPQKPFEIYEEDFKKTIIDFILFEEKIDVKEFNEKLLNQVLYKSEYKDGKLMLDVGEENEENKD
>NZ_CP049227.1|WP_164825143.1|11750_12272_+|N-6-DNA-methylase
MKKIKIDDWKPFEIEKLFTVKRPKSRSVKKYNEGEIPFVSSGNYNNGVDSYREPIDDEDLDKGNCITVSPVDGSTFYQPQDFLGRGGGGSSIMLLYNDNLNKFNGLFIASVIRESLKIKYQYNDMGSSDSIKKENILLPALDDKTPDWNFMEESMKRLETRERERVQAILQAI
>NZ_CP049227.1|WP_164825144.1|12325_12784_+|hypothetical-protein
MDFFSPITVKNKVMIYDIKNFGTTPVYASDSSYKNNIGYIDDEPEFYVNDEQSMYVIFGDHTKSMRIIETNFSVTDNVKVLSPKIKSKNSLFFVMTSWLANIPDLGYSRHWSIAKKTKIKLPVKSDNSPDWEYMERYIENLKLKCNIANYNI
>NZ_CP049227.1|WP_164825145.1|13012_14680_-|hypothetical-protein
MSNKKIIKQLSIPIALAGAMFCTILQQTQKANAAEESPCHAVLTVKYDGRGQVRLLDGNGTYQNQYLAKNTTWKTFAKAMINNLVCYRLGTDKQWIPAKYSDLPDDYSPCKGEGGYVISTPSMTNREELHTVGYTVYSGAGKIRLLDSKGNYMSQYVDKNASYKVFEKGTLNNRILYRIGTDQQWIPSDYFVLDTTVPSASITTTPDIPSAYATPTPDVSSVSVPTMSDISNVSTTTPSDISTTTTPNMSSASVTITPDIPSTSETATPDTPSVSTTTTSDIPSESVTTTPDTQISDDYDIYAGQRGMWTPAQVEEAKKEFVRYVNAFRAKKGLKPFTTDVAWLQEGAEVRGDDILAEYKATGNFSHYRANGKEWDDAFHWTKGALGGENLALVGGSQGEAPKEAAHEIANGFIHEGPDGGHYTVLMGDLDQHPSIGLTFRVVRDADGGYTYLFNMETGTAHNVFGQDCVIKNDELWKWANPWVGMTAPYLYSYLNGVDANGYLHIRRSDMGDTTGYDYSCDLGDKPLPDDQLPAYINAFIEYYRQKYNGKIILD
>NZ_CP049227.1|WP_164825146.1|14874_15690_+|hypothetical-protein
MEKNIGMLANKLDISLVSLEHAIKKIHNLLEIKGKSKKDIKISCEVNKICTKFSELYPISDALEKLICDQYQSTSDLVSLPTIIEEYDLPDQQLYHFVRKEKSNTLIDYLGYNIFLNDKQKYIARRKIKGFLKEFFIFLLSHYASTSGYVLNKNLNIYEEFFAPEEVQVGNSRKGRILGFYKNKDHQQEAIVGFYNGEISFQKQLKKFSINSTSLNFKATQSSQRPIIFSFSLDELLSKDHRFYINMLIESRRNHPFKILYGGGVRRLPND
>NZ_CP049227.1|WP_145999009.1|15655_16180_+|hypothetical-protein
MGGGCADCLTTEFELNVSKFQYDNQSNKGDQKLYKRLFGNINIDNLKDFLLQHMPATESYCSQRKNDPNKLLLGSDLYPITMWTRKGIVDRLTKLGIDGKVPNSILLETLISRQTKICEYDTEEEFINSIDDYLYENYRENNEYITSWERILNTSTPSETLKKIDGILKGRIKL
>NZ_CP049227.1|WP_164825147.1|16202_17018_+|hypothetical-protein
MDNKQIENYKNSDLYTMFHPYTLPKEDDTDLLTVRPIVTDNKVESIPDTNTNNTKAEETEKPATEPVTSQKPQNQVYAKSNTSTYSDSISIPTKKVDSDTETIKTTSEQIEPKSDVSNLLNTVINDEGDLYKKVQDVEKDVDWIKASHQFELTFKKDLISLPVNKITVFDISDHTESYIPFNSILLNHLGSLVIGKELYIILVFRNGQIIQLAPKSWINNNHSLTNSGFHYYYDNLDMDRFLQTLKQLSVSITSTERFTEFWLKYAPIIQK
>NZ_CP049227.1|WP_164825148.1|17417_19004_+|hypothetical-protein
MSNKKIIKQLSIPIALAGAMFCTVLQQTQKVNAAEESPCHAVLTVKYDGRGQVRLLDGNGTYQNQYLAKNTKWKTFAKAMINNLVCYRLGTDKQWIPSKYSDLPDDYSPSKGEGGYVISTPSMTNREELHTVGYTVYNGAGKIRLLDSKGNYMSQYVDKNVSYKVFEKGTLNNRILYRIGTDQQWIPSDYFVLDTTVPSTSVNTTTDIPSVSTTTTSDIPSAYTTTTPDIPSSSVPTMPNVSDVSVTPTPDISSTSVTTTPTSSIQISDDDDIYAGQRGMWTPVQVEEAKQEFVRYVNAFRAKKGLKPFTTDVAWLQEGAEIRGDDILAEYKATGNFSHYRANGKEWDDAFHWTKGALGGENLALVGGSQGEAPKEAAHEIANGFIHEGPDGGHYAVLVGELDQHPSIGLTFRVVRDADGGYTYLFNMETGTAHNVFGQGCIIKNDELWKWAKPWVGMTAPYLYSYLEGEDANGYQHIQVSAMGDTTGYDYRYSPKDAPYLPDDQLQPYIHAFIEYYKKMYHGHVILD
>NZ_CP049227.1|WP_006734626.1|19513_21013_+|ATPase-AAA
MDVNKLLEIKEGSNMELKKAKNQVPKSFWETYSAFANTDGGIVIFGIDEKSKEVTGVTDAYKLRDDLFNILNNPSKVSANIISNKDIKIRELENGLEILIITVPEAPYNLKPIYLNGNPQEAYERLGEGDRKLSSEKFKALIVGAKKETDNELLKNYDLDDLDKETLEMYRKDLYDQTNNEKYKDIDFKEMLIELGAMRKNRQVNNEYLLTTGGLLFFGKYSSITDRFPGFQLDYFEKKSSLDTDWIDRVSTGDMAYPEMNVYKFLKIVLEKLNLTIKDTFILEEDSKTRLPYKSDLLTSVREALVNSLMHAYYDSDKPIKITAYPDYYEFINPGKMRVTVDEFIHGGTSDIRNHTMSSIMRRIGMSEKAGSGGPRIFDVAEKYKLKLPEVIRDQYSTSLRIWKVDLEKIIEKYPSPQKEILLYLIKYQSISRAEAEENLSIENYQFRVAINTLLEEGVIDLIGKGRATRYWLKTSSSEYSYSMKRLLRFVEDNFIGKN

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Crispr_ID: NZ_CP049227_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049227_3

17043-17141

TypeV

Consensus_repeat	Method
AAAATAATCGTGAGTTAATCGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049227_3

>merge|NZ_CP049227|3|17043-17141|CRISPRCasFinder
AAAATAATCGTGAGTTAATCGTGTGAAATAAAACTTCTCAATCAACTCAAATGGCTATAAATAGCCAAAATGAATAAAAATAATCGTGAGTTAATCGTG

>NZ_CP049227|3|3|17043-17141|CRISPRCasFinder
AAAATAATCGTGAGTTAATCGTG	TGAAATAAAACTTCTCAATCAACTCAAATGGCTATAAATAGCCAAAATGAATA
AAAATAATCGTGAGTTAATCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049227.1\|WP_006734626.1\|19513_21013_+\|ATPase-AAA	unknown	unknown	gnl\|CDD\|225420
NZ_CP049227.1\|WP_164825145.1\|13012_14680_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP049227.1\|WP_164825151.1\|30415_31702_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825150.1\|23110_26467_+\|VaFE-repeat-containing-surface-anchored-protein	unknown	unknown	gnl\|CDD\|375630
NZ_CP049227.1\|WP_164825144.1\|12325_12784_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_145999009.1\|15655_16180_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_102215578.1\|31829_32348_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825146.1\|14874_15690_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|366631
NZ_CP049227.1\|WP_006734629.1\|28299_29364_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_CP049227.1\|WP_164825148.1\|17417_19004_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|349398
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	unknown	unknown	gnl\|CDD\|226036
NZ_CP049227.1\|WP_164825180.1\|26842_28093_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NZ_CP049227.1\|WP_164825140.1\|8258_9440_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NZ_CP049227.1\|WP_006734632.1\|21309_21645_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_006734625.1\|29382_30414_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825147.1\|16202_17018_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049227.1\|WP_164825149.1\|21650_22871_-\|ParM/StbA-family-protein	unknown	unknown	gnl\|CDD\|212669

Protein	Function_ID	Function_description	E-value
NZ_CP049227.1\|WP_164825139.1\|5422_8254_+\|TraM-recognition-domain-containing-protein	gnl\|CDD\|226036	COG3505, VirD4, Type IV secretory pathway, VirD4 components [Intracellular trafficking and secretion].	6.26883e-11
NZ_CP049227.1\|WP_164825145.1\|13012_14680_-\|hypothetical-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	3.81974e-05
NZ_CP049227.1\|WP_006734626.1\|19513_21013_+\|ATPase-AAA	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	9.16073e-36
NZ_CP049227.1\|WP_164825149.1\|21650_22871_-\|ParM/StbA-family-protein	gnl\|CDD\|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	2.27698e-34
NZ_CP049227.1\|WP_164825142.1\|9979_11770_+\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	5.47565e-18
NZ_CP049227.1\|WP_164825150.1\|23110_26467_+\|VaFE-repeat-containing-surface-anchored-protein	gnl\|CDD\|375630	pfam18202, TQ, T-Q ester bond containing domain. This domain is found in gram positive bacterial surface proteins. It contains a very unusual isopeptide bond between a conserved N-terminal threonine residue on the first beta strand of the Ig-like fold and and a glutamine residue in the final strand of the domain.	4.07069e-28
NZ_CP049227.1\|WP_164825180.1\|26842_28093_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	5.61055e-07
NZ_CP049227.1\|WP_164825143.1\|11750_12272_+\|N-6-DNA-methylase	gnl\|CDD\|366631	pfam01420, Methylase_S, Type I restriction modification DNA specificity domain. This domain is also known as the target recognition domain (TRD). Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity subunit (this family), two modification (M) subunits and two restriction (R) subunits.	1.29412e-09
NZ_CP049227.1\|WP_164825141.1\|9629_9815_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.91663e-10
NZ_CP049227.1\|WP_164825148.1\|17417_19004_+\|hypothetical-protein	gnl\|CDD\|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	7.77663e-05

>NZ_CP049227.1|WP_164825147.1|16202_17018_+|hypothetical-protein
MDNKQIENYKNSDLYTMFHPYTLPKEDDTDLLTVRPIVTDNKVESIPDTNTNNTKAEETEKPATEPVTSQKPQNQVYAKSNTSTYSDSISIPTKKVDSDTETIKTTSEQIEPKSDVSNLLNTVINDEGDLYKKVQDVEKDVDWIKASHQFELTFKKDLISLPVNKITVFDISDHTESYIPFNSILLNHLGSLVIGKELYIILVFRNGQIIQLAPKSWINNNHSLTNSGFHYYYDNLDMDRFLQTLKQLSVSITSTERFTEFWLKYAPIIQK
>NZ_CP049227.1|WP_145999009.1|15655_16180_+|hypothetical-protein
MGGGCADCLTTEFELNVSKFQYDNQSNKGDQKLYKRLFGNINIDNLKDFLLQHMPATESYCSQRKNDPNKLLLGSDLYPITMWTRKGIVDRLTKLGIDGKVPNSILLETLISRQTKICEYDTEEEFINSIDDYLYENYRENNEYITSWERILNTSTPSETLKKIDGILKGRIKL
>NZ_CP049227.1|WP_164825146.1|14874_15690_+|hypothetical-protein
MEKNIGMLANKLDISLVSLEHAIKKIHNLLEIKGKSKKDIKISCEVNKICTKFSELYPISDALEKLICDQYQSTSDLVSLPTIIEEYDLPDQQLYHFVRKEKSNTLIDYLGYNIFLNDKQKYIARRKIKGFLKEFFIFLLSHYASTSGYVLNKNLNIYEEFFAPEEVQVGNSRKGRILGFYKNKDHQQEAIVGFYNGEISFQKQLKKFSINSTSLNFKATQSSQRPIIFSFSLDELLSKDHRFYINMLIESRRNHPFKILYGGGVRRLPND
>NZ_CP049227.1|WP_164825145.1|13012_14680_-|hypothetical-protein
MSNKKIIKQLSIPIALAGAMFCTILQQTQKANAAEESPCHAVLTVKYDGRGQVRLLDGNGTYQNQYLAKNTTWKTFAKAMINNLVCYRLGTDKQWIPAKYSDLPDDYSPCKGEGGYVISTPSMTNREELHTVGYTVYSGAGKIRLLDSKGNYMSQYVDKNASYKVFEKGTLNNRILYRIGTDQQWIPSDYFVLDTTVPSASITTTPDIPSAYATPTPDVSSVSVPTMSDISNVSTTTPSDISTTTTPNMSSASVTITPDIPSTSETATPDTPSVSTTTTSDIPSESVTTTPDTQISDDYDIYAGQRGMWTPAQVEEAKKEFVRYVNAFRAKKGLKPFTTDVAWLQEGAEVRGDDILAEYKATGNFSHYRANGKEWDDAFHWTKGALGGENLALVGGSQGEAPKEAAHEIANGFIHEGPDGGHYTVLMGDLDQHPSIGLTFRVVRDADGGYTYLFNMETGTAHNVFGQDCVIKNDELWKWANPWVGMTAPYLYSYLNGVDANGYLHIRRSDMGDTTGYDYSCDLGDKPLPDDQLPAYINAFIEYYRQKYNGKIILD
>NZ_CP049227.1|WP_164825144.1|12325_12784_+|hypothetical-protein
MDFFSPITVKNKVMIYDIKNFGTTPVYASDSSYKNNIGYIDDEPEFYVNDEQSMYVIFGDHTKSMRIIETNFSVTDNVKVLSPKIKSKNSLFFVMTSWLANIPDLGYSRHWSIAKKTKIKLPVKSDNSPDWEYMERYIENLKLKCNIANYNI
>NZ_CP049227.1|WP_164825143.1|11750_12272_+|N-6-DNA-methylase
MKKIKIDDWKPFEIEKLFTVKRPKSRSVKKYNEGEIPFVSSGNYNNGVDSYREPIDDEDLDKGNCITVSPVDGSTFYQPQDFLGRGGGGSSIMLLYNDNLNKFNGLFIASVIRESLKIKYQYNDMGSSDSIKKENILLPALDDKTPDWNFMEESMKRLETRERERVQAILQAI
>NZ_CP049227.1|WP_164825142.1|9979_11770_+|N-6-DNA-methylase
MSLRTEDQVRDYAKLVLGFDETEENIEQGTGQITTFNQLGFKGYSDKPDGWYLPKNMNDVAIILETKSEKRDISKQIFIDELMKNIDIISSKYKKTVGILYNGKEIAIYKNKELIRVANKLQHKQYYIDLFKENYIDKNKIFTLTKRINDLLHFKFGIKNLYHRMIFTASALVVERFGGNLEAIKDNGYEPFRNKIYDTLAKSLQDHRRQNLKIDILLEVYSEIKMNIVENQDDINKFIDCIIEIAESINSDNWNGEDVMGIFFNEFNRYKKKSESGQVFTPEHITSFMYDLLEITYNDRLLDATCGSGAFLVKAMANMIKEVGGVNTKEAEDIKQNKLYGIEFDREIFALACANMLIHKDGKTNLEQYDTREKEACKWIKSKNITKVLMNPPYERKYGCKKIVTNVLDNVPVGTKCAFILPDKKLEKDKMQSLLKRHTLDMIIKLPEKLFDEGVTTSVFVFETGKPQKDKKIFACYMEDDGLERVKNQGRHDIKNKWKEIEKYWLEVVRTKVDTKYNTHQWIDSKENLSYQKPQKPFEIYEEDFKKTIIDFILFEEKIDVKEFNEKLLNQVLYKSEYKDGKLMLDVGEENEENKD
>NZ_CP049227.1|WP_164825141.1|9629_9815_-|IS3-family-transposase
MFRKGHCHDNAVMENFFGLFKQEIYYGVTYYSYDYLKLEIKRYIKYYNEQRIKEKLNTFYQ
>NZ_CP049227.1|WP_164825140.1|8258_9440_+|hypothetical-protein
MSIKKLILEPTVLNIWKYRPLSQCIKKDSTSGVLVINDIYQADAVKDTGGILINDKGPDLLFNIQNLSTKNLQLLVDSYFEVPLPNPCVFTKKTILFFLQLLVLNAKKKKTSIYEELKNWYQLSDTEISKYMDALNIDINSEIKNIFSKNPQYVEAIVSFLWKCHGFESHHEINLSQDKNILVIPVSLLTKYYYLVVLHYFYKQNWNIFFDTDVPFSLVQEFVVQGSSADIYACRYSNDPLIATLASQADEMWSTAQGDPTTFFNWVGKKAPEALKNYSLTNMKRLLSGLNYSSFLSKYFILSDKTIMLARLQENSEWEAKPFDLDFLISQTIDKGNKDIETLSKKIESLSAKVDQLSDICNKATLTDSEGLNKQFDEMLKKQGNNDNFIDFM
>NZ_CP049227.1|WP_164825139.1|5422_8254_+|TraM-recognition-domain-containing-protein
MFEYIRMQVEKKYNSFSSLLSNQDLKTNLLLFDTIRTFCWLADFVVWFLCFMQIFAPMLNLNFQIINIFCWLVVAICLIGAVNVNWFMILFTTRRLDIDQDDRADVMWKILQSSFWQISFICGSAIAIPLCMTVFPFIQYLRLHPVIPGWTPQMTDMVAGSPFILRALLFGVPIIFTFYLHVRFQYLASVFEQRIKDWMKVYEFKYKCMHDTLTGKDMADVKKDKKEPSIILGDSLETGDAIIQSPIARRQNSIVTGPIGAGKTSAWFLNQILQDINHMIRFMRDYATVSQDPDWNKPFGMQQNYLCGFAVIETTGDLCNTVLRYALKKGIPREKIIYYNPEDPNTPSFSLLNGPVETATQTLTDIMSGLKKNANDFFSMQERTHLTQYIFLLKESSIIDSKPADFGELMKMYNDVYVVIDKREKLRTYCKILENQIDKLNRQKCDNDQAQHKIDVAIEEIQDKLAVNRETLAWFDSNIVSLQFKTGVKLLQQEGPHKGEPVYVDKNMEFIGGLISQLTELSKKMGLRRVLFRDKVDFSLDDAMKNGCIILCNTAKDMLGETSARMLGQIYSLAFQGATFRRTPNVDPMFPIYQDEFPDYLYDNFTDFAAQARKYNVPLNIGAQSPAQLSKKFGPDFLRTIFSVMLTRATFGDMGYDDALVLSRLFGTHKEAIESINEQDIDLAADCARNRKMISSRLQEVPNISPEEIMGLEKFTMAVRLPGEHRSDVFDRVRVRRITDEMVENDPENFDINGKDKKAYEDMKALEVHTNKDFDNIDKQIIQKIKDGTIKLSTSNTVKSPAKFDRVVKNSSSNAVTDLPQSMDDFEQVFSNQEKEAAFNAVDDSVTKSGNCGNNRFNNNISIANDISSAKDLPSDNKTVAESSKVTKANKKPSLDDSIKTMHNIPVSKLFSQDSLREYDQEEPFDGKDPFNSQPGMDDNESR
>NZ_CP049227.1|WP_164825148.1|17417_19004_+|hypothetical-protein
MSNKKIIKQLSIPIALAGAMFCTVLQQTQKVNAAEESPCHAVLTVKYDGRGQVRLLDGNGTYQNQYLAKNTKWKTFAKAMINNLVCYRLGTDKQWIPSKYSDLPDDYSPSKGEGGYVISTPSMTNREELHTVGYTVYNGAGKIRLLDSKGNYMSQYVDKNVSYKVFEKGTLNNRILYRIGTDQQWIPSDYFVLDTTVPSTSVNTTTDIPSVSTTTTSDIPSAYTTTTPDIPSSSVPTMPNVSDVSVTPTPDISSTSVTTTPTSSIQISDDDDIYAGQRGMWTPVQVEEAKQEFVRYVNAFRAKKGLKPFTTDVAWLQEGAEIRGDDILAEYKATGNFSHYRANGKEWDDAFHWTKGALGGENLALVGGSQGEAPKEAAHEIANGFIHEGPDGGHYAVLVGELDQHPSIGLTFRVVRDADGGYTYLFNMETGTAHNVFGQGCIIKNDELWKWAKPWVGMTAPYLYSYLEGEDANGYQHIQVSAMGDTTGYDYRYSPKDAPYLPDDQLQPYIHAFIEYYKKMYHGHVILD
>NZ_CP049227.1|WP_006734626.1|19513_21013_+|ATPase-AAA
MDVNKLLEIKEGSNMELKKAKNQVPKSFWETYSAFANTDGGIVIFGIDEKSKEVTGVTDAYKLRDDLFNILNNPSKVSANIISNKDIKIRELENGLEILIITVPEAPYNLKPIYLNGNPQEAYERLGEGDRKLSSEKFKALIVGAKKETDNELLKNYDLDDLDKETLEMYRKDLYDQTNNEKYKDIDFKEMLIELGAMRKNRQVNNEYLLTTGGLLFFGKYSSITDRFPGFQLDYFEKKSSLDTDWIDRVSTGDMAYPEMNVYKFLKIVLEKLNLTIKDTFILEEDSKTRLPYKSDLLTSVREALVNSLMHAYYDSDKPIKITAYPDYYEFINPGKMRVTVDEFIHGGTSDIRNHTMSSIMRRIGMSEKAGSGGPRIFDVAEKYKLKLPEVIRDQYSTSLRIWKVDLEKIIEKYPSPQKEILLYLIKYQSISRAEAEENLSIENYQFRVAINTLLEEGVIDLIGKGRATRYWLKTSSSEYSYSMKRLLRFVEDNFIGKN
>NZ_CP049227.1|WP_006734632.1|21309_21645_-|hypothetical-protein
MNKAKNDDRKNFTLRIPKNSPEAKWLQHQKNSTESMTFLISLAIANYGNTDLIQMAKQVVVQNINFSLDPSQNETKNSPEVKKNNDMKLKTPNQKTDKEKNISLLGDPRLS
>NZ_CP049227.1|WP_164825149.1|21650_22871_-|ParM/StbA-family-protein
MKNSLMSVANDLGYGDVKININNTFIKQPSVVAEVQQVTSDPVVSTNDQAVAKVIKNLLNNLDITIDKKRYLVGTAASNSTLPRKAFDINSGSGKANTELALILPLALIAAKKVQEAYDNQEDIFEPLKVDVVMTTALPITEIGFGSSDTRDKFAQRFTAKKHIVILNTFDNPISVTISFKAVSVFKEGEVATAIAIPHGNEDLQKELINDIKKNYPDQAANAEQLIKTAKDVLGIDIGQGTTDLALTTKGKADVYNSESIPEGYGTVLRRAWKFLPRMQNGYSLPDEVSLREILNSEPTNQIDKENKETALEAVQTSVPSLIDRIESGFNDALSANFDLEVVYIFGGGSIPLIKQTDLRNQLAESLKRKRSKALIVWVGEKYAQKLNEMGLKLLVDDLAAQYTNR
>NZ_CP049227.1|WP_164825150.1|23110_26467_+|VaFE-repeat-containing-surface-anchored-protein
MKFDNFSSLTTIKEHVKERKGMKFMSALTMALPMFLGTGVKVFADAPSGYKYHDSLPQQVIYPTSENLTKSYASFNCRLVYKGGVIQPDPGIAAIWQSDQGDQMFCTEPYMKTPHGTYTNATYKQTDPYMVAVLRAGWPCRSSQELGLGNDTVAAFYATQLAVWTAHAHDKTASTQIMPETIQWRSPNGTATQAECLAVRHAYEKILSDARVMQSERPISTIELQSVGDTDESDVETQGKWSSSKTFRVITKNENRKPEAVTAKFIISATAVPGTTKVWQDGKLVGQGTADSSGNLTITGNIKTNDTITIETPTEDHQAMVNVSVSSQKVYELVGMGVSGNYAQHEQSSMGLIALKSQPITASKPYSFKGHPIKIIVHKKDNRGKEGNALAGVTFKLYRAATQKSDQTDLGSYIGSYTTDQDGSFSTKGLPYGYYVLVEDSVPKNIKIDRTPQPIDATYKSLKQTNGVLHVDYGPIINQYKDVNVTSTATNLEDGSKYAQPIQGPVVINENLHFSHLQTVAPYKVHAWLVDQETGQPIMINGKKIEVTKDFGSKTQDSNPDGLEQDLAVQLKIPNASSLAGKNVVVFCEGEETESTTDGKKYDYVHKDLNDKTETVHFTKPSLHTKALNKETGSNILQPTDGEKLVDTVIYKELIPGKTYTIKGIVVDKETGKAVLNNGKKVIFTKTFTANDSNGEVNAEVTFDDHHYWNHDLVVYETIYYTTYELAKHRDINAPSQTMHVSHPRMHSTLAYNGQKLVYASARNVVEDVIRYVDLIPGTEYTIRGQLMDQVTGLPVVKDGMPIIATARFTPNRPNGTITVDFKFNGKPYVGHNLVAFETIYADGRVVLEHADLNDASESILVDHYKRHPFIPYIIPRPQPHNSEIIVINNNNNNNNNNNNSSNNNSSNNGNNSNSSDSSDTIHHGRHVRHLLHHRGILHPSTVNIISKSANIGSGNSDGGNNTATNTSTPNTISKSDTNDSGNSTTGSGSGSDNTMPHTIKQSGNTGSTNADAYSDGSYGKDSRSNNSNPNTVNQFGTNNSNNAPADSNASLAHKAINKAYKILPNKIDTSDDNTALPQTGSENNPLADLIGIGFVTVVASAAVEFINGKDKNAKAMK
>NZ_CP049227.1|WP_164825180.1|26842_28093_+|class-I-SAM-dependent-methyltransferase
MNKIAEELNRYPQDYWDFKGTTKSGIHNIGKYPATMVPDMQYQLLSVVSKHLNNKNITLLDPFCGSGTTLVIAQELGINSVGIDINPYATLLSFVKTNKYDKADVYNAISTIKSNLEQGLNFPIFDFYNIKKWFRDDIIKSLSQIRHCILLEKSQDIRKFFWICLSEVIFKFSNDRTSTFKLHALPKQKINLIEDKCIEYFIKIIKDNSEHLNYSNTTSSNIIYGDSSSIINNKLKREFDIICTSPPYGDNPTTITYGQASILFLKWIDSKDLSCSQELLEKYTTIDKISVGGKKRKIINTKDIKSLQDFLGKISLKKQAKVINFFEDYYVSLKCMNKCLAKSGYLIMTVGNRSVDAVRQPLDNITIEILESFGLKLVSKFNRNILYKNSPLKLSLLKDKKTIKTIQKETIIIFTK
>NZ_CP049227.1|WP_006734629.1|28299_29364_+|hypothetical-protein
MDNQNLDELNTQVSDVADNTVPLFEDVAETIPKNALDYMGNLKRGCYTNLDPDNLVFAVGVEVFSARVKQGSDLVTMPVLKMLISDEKIQAPIYVFAPEAGSNYRNLSNYIDHKVKVAVSTLRYINNKYIAEGSIRQAEYIIGKKLFDTFNKDPEKFKSEERLGTITQVIDTTAFGCVFFEYEGMQLGMLARNYYYQTWTTPLSTVAQIGYKIPFKIEDIKATTYEEQDGVKRDIANHLPVPKGIMYQIITTRLPFLPSPDTIVSNLLKKNAEFKANIVGCHPIKGILVEIAPGWVIKGFLNSRSPFKPSSEDAKQHTAVVVRLMKLDQATKTGRCLILRFPHGVAKTIDPHNH
>NZ_CP049227.1|WP_006734625.1|29382_30414_+|hypothetical-protein
MEDVYHSVDLKDNQFINNKTGLAMLPSLINAEDETTFSIKRDFFLKDYVTLRDSIKAIKKYEIADQYNIVLERMSTQAEYWLKFIGMFKSVQLLQLKRNARMFPALLTEKGISKALKFLMLNGLIIRWKYYHPINGTDIPVYTLSGNGFRFLKYFYNEKYFNPQNFFNLDARFHLRFWEVLDVYQMLISLPVYHASSTMFKGYHSEDKAILPSPLQVNLELIHGQPKNLVFYPALHSDGSDYYKNAVIKWKNFVEKDDDIDLTKTINDLPSGQNVLTFYTPTLARANELNEILCLKEFRFPSLFLVGTQISNAGLPKAFFMPDRENNGLRALDFEDILKKEAI
>NZ_CP049227.1|WP_164825151.1|30415_31702_+|hypothetical-protein
MFGQKSKLTVVLFLATVLLSGCANNKMPDLTNKNSSSKVDQEKQPTVAIALARGKILQSSGLITIPVVLKNIGSNSTVISSKNFTLEVQGHKFNTFNAPGEASDYHQDFDSNRIWNNTLSFYLGTTLTPKQLQHVKLFYQMDNGKEIQAKVLTTSTNQNNIRSNLNNDMKSIGTYYSDITSFVKKNKEGEDISLKDSFSDPDYDKFKTWIVVPKKDPHNIIIKVLNQSNTDISISFNNIELVDRNNVETRVAPSYRNYFLIIPHGKYAMASVPMESKLDVSRKPFSTKVRADDNDFFSTQDAIYPIETVISSNGKDINSLFSLTPKEYKKCNISWSKPVLDFENNKLSVTVELKDYFALHAKAKAFSLVGVNKDKTIGDKEYCCKLSPAKITKSDPTDMILSFKDLSLLKTYSNIELRYKNSKIMQIK
>NZ_CP049227.1|WP_102215578.1|31829_32348_+|hypothetical-protein
MSKLLKPTTSYERALMQTCIFHSEVFEEHQKHCEYGCDLCAPIRKELERAQSKRNTSIANVPYDECLELRAEIQREDKIRNFYPSVDDIRLANGAISREVYLVLQVMDFSDSEIRKYFHINHHEWQNFKKREFPNWLEDRDDILSEEAQEAYLNWRAKHNVASSKSSKHHWM

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP049227_2	2.1\|9544\|53\|NZ_CP049227\|CRISPRCasFinder	9544-9596	53	NZ_CP049226.1	167340-167392	2	0.962
NZ_CP049227_2	2.1\|9544\|53\|NZ_CP049227\|CRISPRCasFinder	9544-9596	53	NZ_CP049226.1	440320-440372	2	0.962
NZ_CP049227_2	2.1\|9544\|53\|NZ_CP049227\|CRISPRCasFinder	9544-9596	53	NZ_CP049226.1	577554-577606	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049227.1	19305-19357	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049227.1	19392-19444	2	0.962

1. spacer 2.1|9544|53|NZ_CP049227|CRISPRCasFinder matches to position: 167340-167392, mismatch: 2, identity: 0.962

tttttatttattttggctatttatagccatttgagttaattgggaagttttat	CRISPR spacer
tttttatttattttggctatttatagccatttgagttgattaggaagttttat	Protospacer
*************************************.***.***********

2. spacer 2.1|9544|53|NZ_CP049227|CRISPRCasFinder matches to position: 440320-440372, mismatch: 2, identity: 0.962

tttttatttattttggctatttatagccatttgagttaattgggaagttttat	CRISPR spacer
tttttatttattttggctatttatagccatttgagttgattggggagttttat	Protospacer
*************************************.******.********

3. spacer 2.1|9544|53|NZ_CP049227|CRISPRCasFinder matches to position: 577554-577606, mismatch: 2, identity: 0.962

tttttatttattttggctatttatagccatttgagttaattgggaagttttat	CRISPR spacer
tttttatttattttggctatttatagccatttgagttgattaggaagttttat	Protospacer
*************************************.***.***********

4. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to position: 19305-19357, mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

5. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to position: 19392-19444, mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049227_1	1.1\|1758\|60\|NZ_CP049227\|CRISPRCasFinder	1758-1817	60	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	1758-1817	0	1.0
NZ_CP049227_2	2.1\|9544\|53\|NZ_CP049227\|CRISPRCasFinder	9544-9596	53	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	9544-9596	0	1.0
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	17066-17118	0	1.0
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	19305-19357	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049227	Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence	19392-19444	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	38279-38331	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	38453-38505	2	0.962
NZ_CP049227_3	3.1\|17066\|53\|NZ_CP049227\|CRISPRCasFinder	17066-17118	53	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	38616-38668	2	0.962

1. spacer 1.1|1758|60|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 0, identity: 1.0

tattttatgcatccttatatggttatatatcgcatgtattaatgtattttatgcatccct	CRISPR spacer
tattttatgcatccttatatggttatatatcgcatgtattaatgtattttatgcatccct	Protospacer
************************************************************

2. spacer 2.1|9544|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 0, identity: 1.0

tttttatttattttggctatttatagccatttgagttaattgggaagttttat	CRISPR spacer
tttttatttattttggctatttatagccatttgagttaattgggaagttttat	Protospacer
*****************************************************

3. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 0, identity: 1.0

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	Protospacer
*****************************************************

4. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

5. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049227 (Lactobacillus iners strain C0011D1 plasmid pC0011D1, complete sequence) position: , mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

6. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

7. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

8. spacer 3.1|17066|53|NZ_CP049227|CRISPRCasFinder matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 2, identity: 0.962

tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaatgaata	CRISPR spacer
tgaaataaaacttctcaatcaactcaaatggctataaatagccaaaataagta	Protospacer
************************************************.*.**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

9629 : 59621

Bacillus_phage(20.0%)

integrase,transposase

attL 35262:35278|attR 58681:58697

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164825141.1\|9629_9815_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.3e-09	55.4
WP_164825142.1\|9979_11770_+	N-6 DNA methylase	NA	NA	NA	NA
WP_164825143.1\|11750_12272_+	N-6 DNA methylase	NA	NA	NA	NA
WP_164825144.1\|12325_12784_+	hypothetical protein	NA	NA	NA	NA
WP_164825145.1\|13012_14680_-	hypothetical protein	NA	NA	NA	NA
WP_164825146.1\|14874_15690_+	hypothetical protein	NA	NA	NA	NA
WP_145999009.1\|15655_16180_+	hypothetical protein	NA	NA	NA	NA
WP_164825147.1\|16202_17018_+	hypothetical protein	NA	NA	NA	NA
WP_164825148.1\|17417_19004_+	hypothetical protein	NA	NA	NA	NA
WP_006734626.1\|19513_21013_+	ATPase AAA	NA	NA	NA	NA
WP_006734632.1\|21309_21645_-	hypothetical protein	NA	NA	NA	NA
WP_164825149.1\|21650_22871_-	ParM/StbA family protein	NA	NA	NA	NA
WP_164825150.1\|23110_26467_+	VaFE repeat-containing surface-anchored protein	NA	NA	NA	NA
WP_164825180.1\|26842_28093_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_006734629.1\|28299_29364_+	hypothetical protein	NA	NA	NA	NA
WP_006734625.1\|29382_30414_+	hypothetical protein	NA	NA	NA	NA
WP_164825151.1\|30415_31702_+	hypothetical protein	NA	NA	NA	NA
WP_102215578.1\|31829_32348_+	hypothetical protein	NA	NA	NA	NA
WP_164825152.1\|32501_33830_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	7.3e-57	36.8
WP_006734667.1\|34117_34678_+	hypothetical protein	NA	NA	NA	NA
WP_164825153.1\|34826_35096_+	hypothetical protein	NA	NA	NA	NA
35262:35278	attL	NA	NA	NA	NA
WP_164825154.1\|35321_36827_+	DUF3854 domain-containing protein	NA	NA	NA	NA
WP_164824143.1\|37320_37500_+	hypothetical protein	NA	NA	NA	NA
WP_164825155.1\|37659_38490_+	hypothetical protein	NA	NA	NA	NA
WP_102215561.1\|38579_39401_+	hypothetical protein	NA	NA	NA	NA
WP_164825156.1\|39444_40356_+	hypothetical protein	NA	NA	NA	NA
WP_164824147.1\|40420_40834_+	hypothetical protein	NA	NA	NA	NA
WP_164825157.1\|40929_41358_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	9.3e-30	46.2
WP_164798948.1\|41450_41621_+	hypothetical protein	NA	NA	NA	NA
WP_102215558.1\|41717_41936_+	hypothetical protein	NA	NA	NA	NA
WP_164825181.1\|42064_42484_+	hypothetical protein	NA	NA	NA	NA
WP_006734556.1\|42527_42902_+	hypothetical protein	NA	NA	NA	NA
WP_164824150.1\|42913_43249_+	hypothetical protein	NA	NA	NA	NA
WP_164825158.1\|43317_44370_+	hypothetical protein	NA	NA	NA	NA
WP_164825159.1\|44382_46632_+	hypothetical protein	NA	NA	NA	NA
WP_164825160.1\|46643_51122_+	type IV secretion system protein	NA	NA	NA	NA
WP_164825161.1\|51248_51857_+	hypothetical protein	NA	NA	NA	NA
WP_164825162.1\|52191_53076_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_164825163.1\|53145_53754_+	hypothetical protein	NA	NA	NA	NA
WP_164825164.1\|53828_54437_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XCL7	Enterococcus_phage	7.3e-20	72.6
WP_164798958.1\|54617_54824_+	hypothetical protein	NA	NA	NA	NA
WP_164825165.1\|54837_55518_+	class A sortase	NA	NA	NA	NA
WP_164825166.1\|55821_56463_+\|integrase	tyrosine-type recombinase/integrase	E2ELN7	Clostridium_phage	7.2e-18	34.5
WP_006734559.1\|56809_57367_+	hypothetical protein	NA	NA	NA	NA
WP_006734566.1\|57393_58161_+	hypothetical protein	NA	NA	NA	NA
WP_164825167.1\|58715_59621_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
58681:58697	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP049226

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

2. NZ_CP049227

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection