CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049229	Lactobacillus iners strain C0210C1 plasmid pC0210C1, complete sequence	0 crisprs	cas14k	0	0	1	0
NZ_CP049228	Lactobacillus iners strain C0210C1 chromosome, complete genome	1 crisprs	cas8e,cse2gr11,cas7,cas5,cas6e,cas1,DEDDh,DinG,cas3	0	11	7	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

33262 : 99591

Lactobacillus_phage(30.0%)

integrase,transposase

attL 24659:24718|attR 52608:52672

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
24659:24718	attL	NA	NA	NA	NA
WP_164824148.1\|33262_33691_-\|transposase	IS200/IS605 family transposase	A0A0P0IQC6	Lactobacillus_phage	9.3e-30	46.2
WP_164798948.1\|33783_33954_+	hypothetical protein	NA	NA	NA	NA
WP_102215558.1\|34051_34270_+	hypothetical protein	NA	NA	NA	NA
WP_006734557.1\|34398_34818_+	hypothetical protein	NA	NA	NA	NA
WP_164824149.1\|34861_35236_+	hypothetical protein	NA	NA	NA	NA
WP_164824150.1\|35247_35583_+	hypothetical protein	NA	NA	NA	NA
WP_164824183.1\|35651_36704_+	hypothetical protein	NA	NA	NA	NA
WP_164824151.1\|36716_38966_+	hypothetical protein	NA	NA	NA	NA
WP_164824152.1\|38977_43456_+	type IV secretion system protein	NA	NA	NA	NA
WP_145999005.1\|43465_44185_+	hypothetical protein	NA	NA	NA	NA
WP_006734564.1\|44562_45045_+	hypothetical protein	NA	NA	NA	NA
WP_164824153.1\|45119_45728_-	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	3.7e-24	42.3
WP_164798958.1\|45908_46115_+	hypothetical protein	NA	NA	NA	NA
WP_164824154.1\|46128_46809_+	class A sortase	NA	NA	NA	NA
WP_006734569.1\|47289_47931_+\|integrase	tyrosine-type recombinase/integrase	E2ELN7	Clostridium_phage	1.9e-18	35.0
WP_006734559.1\|48277_48835_+	hypothetical protein	NA	NA	NA	NA
WP_006734566.1\|48861_49629_+	hypothetical protein	NA	NA	NA	NA
WP_164824155.1\|49780_50686_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_006735138.1\|50890_51055_+	hypothetical protein	NA	NA	NA	NA
WP_164824156.1\|51285_52377_+	tyrosine recombinase XerS	A0A1B1IQT7	uncultured_Mediterranean_phage	3.1e-05	23.6
WP_164824157.1\|52668_53001_-	hypothetical protein	NA	NA	NA	NA
52608:52672	attR	NA	NA	NA	NA
WP_164824158.1\|53377_54658_-	preprotein translocase subunit SecY	NA	NA	NA	NA
WP_102215542.1\|54667_57019_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_164824184.1\|57218_57452_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_006734916.1\|58008_58566_-	hypothetical protein	NA	NA	NA	NA
WP_164824159.1\|58740_59655_+	LysM peptidoglycan-binding domain-containing protein	D2KRB9	Lactobacillus_phage	3.8e-12	31.3
WP_164824160.1\|59898_60240_-	hypothetical protein	NA	NA	NA	NA
WP_164824161.1\|60245_60848_-	hypothetical protein	NA	NA	NA	NA
WP_164824162.1\|61269_63516_-	hypothetical protein	A0A1X9I6W8	Streptococcus_phage	2.9e-37	26.1
WP_164824163.1\|63524_65576_-	hypothetical protein	NA	NA	NA	NA
WP_164824164.1\|65585_66848_-	hypothetical protein	NA	NA	NA	NA
WP_164824165.1\|66867_67854_-	hypothetical protein	NA	NA	NA	NA
WP_164824166.1\|67979_68756_-	hypothetical protein	NA	NA	NA	NA
WP_164824167.1\|68945_69659_-	hypothetical protein	NA	NA	NA	NA
WP_102215533.1\|70571_71330_-	hypothetical protein	NA	NA	NA	NA
WP_164824168.1\|71610_74469_+	hypothetical protein	NA	NA	NA	NA
WP_102215531.1\|75290_75863_+	single-stranded DNA-binding protein	B8R683	Lactobacillus_phage	1.0e-23	47.2
WP_102215530.1\|76176_77019_-	Eco47II family restriction endonuclease	NA	NA	NA	NA
WP_102215529.1\|77022_78021_-	DNA (cytosine-5-)-methyltransferase	F2Y148	Organic_Lake_phycodnavirus	1.6e-88	48.9
WP_164798920.1\|78029_78194_-	hypothetical protein	NA	NA	NA	NA
WP_164824169.1\|79069_81172_-	penicillin-binding protein	NA	NA	NA	NA
WP_164824170.1\|82020_83490_+	replication initiation protein	NA	NA	NA	NA
WP_164824171.1\|83661_85158_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_006734637.1\|85266_86211_-	DNA-entry nuclease	NA	NA	NA	NA
WP_006734645.1\|86236_86716_-	hypothetical protein	NA	NA	NA	NA
WP_006734644.1\|86705_87020_-	hypothetical protein	NA	NA	NA	NA
WP_102215527.1\|87125_87542_+	hypothetical protein	NA	NA	NA	NA
WP_164824172.1\|87624_88233_-	signal peptidase I	NA	NA	NA	NA
WP_006734643.1\|88372_88816_+	hypothetical protein	NA	NA	NA	NA
WP_157750138.1\|89165_89585_-	hypothetical protein	NA	NA	NA	NA
WP_042745926.1\|89797_92839_+	MucBP domain-containing protein	NA	NA	NA	NA
WP_164798924.1\|93398_94313_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_164798925.1\|94410_95265_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_102215522.1\|95650_96910_+	M23 family metallopeptidase	Q6SEC2	Lactobacillus_prophage	1.6e-24	42.9
WP_164824173.1\|96923_97559_+	hypothetical protein	NA	NA	NA	NA
WP_006734920.1\|97558_98200_+	hypothetical protein	NA	NA	NA	NA
WP_164824174.1\|98265_99591_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	1.9e-57	37.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP049228

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049228_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049228_1

395937-397372

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
GTATTTCCCGCACATGCGGGGGTGATCC	PILER-CR
GTATTTCCCGCACATGCGGGGGTGATCC	CRISPRCasFinder
GTATTTCCCGCACATGCGGGGGTGATCC	CRT

23 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP049228_1

>merge|NZ_CP049228|1|395937-397372|PILER-CR,CRISPRCasFinder,CRT
GTATTTCCCGCACATGCGGGGGTGATCCCAATTGAAAGAGAAAAGCGACGGCGAAGACTGGGTATTTCCCGCACATGCGGGGGTGATCCTATAGTCAAAAGCCAGTCACCTCTGCAGCAGTAGTATTTCCCGCACATGCGGGGGTGATCCTCTGCGCTGCACCTTTCGGGTTTCGGTAAGCTAGTATTTCCCGCACATGCGGGGGTGATCCCGGCTGTTTATTTTTTTATTCTTAACTCTTTTAGTATTTCCCGCACATGCGGGGGTGATCCTTGTAAAGAGAAAAGGAAAGAGGAAAAGAAAATGGTATTTCCCGCACATGCGGGGGTGATCCTAATTCAAATCCTTCTTTTAACAATTTACACATAAGTATTTCCCGCACATGCGGGGGTGATCCTGCGAGCTAGAAGATAAAATCAATGAATTTTTTGTATTTCCCGCACATGCGGGGGTGATCCCTCATTTTGTGTATCTTTTTTAGTTTCTTCAAGGTATTTCCCGCACATGCGGGGGTGATCCTGGTTTTTAGCTAAGGGCAACAAAGATATTTCAGTATTTCCCGCACATGCGGGGGTGATCCTGCTCTAATTTCGTTGTTTTCAAAATTGAATTTGTATTTCCCGCACATGCGGGGGTGATCCTATAGCTTGCTTGCACTGCACCTTTAGCGAGTGGTATTTCCCGCACATGCGGGGGTGATCCCTATGGGAAGTTTTTACTTTTCTATGTCAATGCGGTATTTCCCGCACATGCGGGGGTGATCCCAGCGTTATTATATAAGTATAAAGAGAAAAGGAGTATTTCCCGCACATGCGGGGGTGATCCTGGAAAACAACAATGCGGACTGGAAAGGCAGATGTATTTCCCGCACATGCGGGGGTGATCCTCAGCAAAGTAGCAAACGTATGACGAAAACCATGTATTTCCCGCACATGCGGGGGTGATCCTAGACGCACTTACGCAAAGTATGACTTACTTTTGTATTTCCCGCACATGCGGGGGTGATCCTACACACTATGAGCATGAGTGTGATTAGCTTCAGTATTTCCCGCACATGCGGGGGTGATCCCGATCAATTTTTGGAAAGCGGGGAGTATATAGGGTATTTCCCGCACATGCGGGGGTGATCCTGCTTGTGCTAAACCTTGTACATTTTTCATCAAGTATTTCCCGCACATGCGGGGGTGATCCTACTTGCGTCGGTATGTAGCCCGTTCCAGTTATGTATTTCCCGCACATGCGGGGGTGATCCTGACCAACTAAAAGATTTAGCAGGCATGGTAAAGTATTTCCCGCACATGCGGGGGTGATCCGCTACCGAGGGAGTAAATTATGTAAACCCGTCAGTATTTCCCGCACATGCGGGGGTGATCCTCAACGCTTACTTCAAAGTAATAAAGTCACTTTAGTATTTCCCGCACATGCGGGTGACGATT

>NZ_CP049228|1|1|395937-397310|PILER-CR
GTATTTCCCGCACATGCGGGGGTGATCC	CAATTGAAAGAGAAAAGCGACGGCGAAGACTGG
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGTCAAAAGCCAGTCACCTCTGCAGCAGTA
GTATTTCCCGCACATGCGGGGGTGATCC	TCTGCGCTGCACCTTTCGGGTTTCGGTAAGCTA
GTATTTCCCGCACATGCGGGGGTGATCC	CGGCTGTTTATTTTTTTATTCTTAACTCTTTTA
GTATTTCCCGCACATGCGGGGGTGATCC	TTGTAAAGAGAAAAGGAAAGAGGAAAAGAAAATG
GTATTTCCCGCACATGCGGGGGTGATCC	TAATTCAAATCCTTCTTTTAACAATTTACACATAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCGAGCTAGAAGATAAAATCAATGAATTTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	CTCATTTTGTGTATCTTTTTTAGTTTCTTCAAG
GTATTTCCCGCACATGCGGGGGTGATCC	TGGTTTTTAGCTAAGGGCAACAAAGATATTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTCTAATTTCGTTGTTTTCAAAATTGAATTT
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGCTTGCTTGCACTGCACCTTTAGCGAGTG
GTATTTCCCGCACATGCGGGGGTGATCC	CTATGGGAAGTTTTTACTTTTCTATGTCAATGCG
GTATTTCCCGCACATGCGGGGGTGATCC	CAGCGTTATTATATAAGTATAAAGAGAAAAGGA
GTATTTCCCGCACATGCGGGGGTGATCC	TGGAAAACAACAATGCGGACTGGAAAGGCAGAT
GTATTTCCCGCACATGCGGGGGTGATCC	TCAGCAAAGTAGCAAACGTATGACGAAAACCAT
GTATTTCCCGCACATGCGGGGGTGATCC	TAGACGCACTTACGCAAAGTATGACTTACTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	TACACACTATGAGCATGAGTGTGATTAGCTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	CGATCAATTTTTGGAAAGCGGGGAGTATATAGG
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTTGTGCTAAACCTTGTACATTTTTCATCAA
GTATTTCCCGCACATGCGGGGGTGATCC	TACTTGCGTCGGTATGTAGCCCGTTCCAGTTAT
GTATTTCCCGCACATGCGGGGGTGATCC	TGACCAACTAAAAGATTTAGCAGGCATGGTAAA
GTATTTCCCGCACATGCGGGGGTGATCC	GCTACCGAGGGAGTAAATTATGTAAACCCGTCA
GTATTTCCCGCACATGCGGGGGTGATCC

>NZ_CP049228|1|1|395937-397372|CRISPRCasFinder
GTATTTCCCGCACATGCGGGGGTGATCC	CAATTGAAAGAGAAAAGCGACGGCGAAGACTGG
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGTCAAAAGCCAGTCACCTCTGCAGCAGTA
GTATTTCCCGCACATGCGGGGGTGATCC	TCTGCGCTGCACCTTTCGGGTTTCGGTAAGCTA
GTATTTCCCGCACATGCGGGGGTGATCC	CGGCTGTTTATTTTTTTATTCTTAACTCTTTTA
GTATTTCCCGCACATGCGGGGGTGATCC	TTGTAAAGAGAAAAGGAAAGAGGAAAAGAAAATG
GTATTTCCCGCACATGCGGGGGTGATCC	TAATTCAAATCCTTCTTTTAACAATTTACACATAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCGAGCTAGAAGATAAAATCAATGAATTTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	CTCATTTTGTGTATCTTTTTTAGTTTCTTCAAG
GTATTTCCCGCACATGCGGGGGTGATCC	TGGTTTTTAGCTAAGGGCAACAAAGATATTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTCTAATTTCGTTGTTTTCAAAATTGAATTT
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGCTTGCTTGCACTGCACCTTTAGCGAGTG
GTATTTCCCGCACATGCGGGGGTGATCC	CTATGGGAAGTTTTTACTTTTCTATGTCAATGCG
GTATTTCCCGCACATGCGGGGGTGATCC	CAGCGTTATTATATAAGTATAAAGAGAAAAGGA
GTATTTCCCGCACATGCGGGGGTGATCC	TGGAAAACAACAATGCGGACTGGAAAGGCAGAT
GTATTTCCCGCACATGCGGGGGTGATCC	TCAGCAAAGTAGCAAACGTATGACGAAAACCAT
GTATTTCCCGCACATGCGGGGGTGATCC	TAGACGCACTTACGCAAAGTATGACTTACTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	TACACACTATGAGCATGAGTGTGATTAGCTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	CGATCAATTTTTGGAAAGCGGGGAGTATATAGG
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTTGTGCTAAACCTTGTACATTTTTCATCAA
GTATTTCCCGCACATGCGGGGGTGATCC	TACTTGCGTCGGTATGTAGCCCGTTCCAGTTAT
GTATTTCCCGCACATGCGGGGGTGATCC	TGACCAACTAAAAGATTTAGCAGGCATGGTAAA
GTATTTCCCGCACATGCGGGGGTGATCC	GCTACCGAGGGAGTAAATTATGTAAACCCGTCA
GTATTTCCCGCACATGCGGGGGTGATCC	TCAACGCTTACTTCAAAGTAATAAAGTCACTTTA
GTATTTCCCGCACATGCGGGTGACGATT

>NZ_CP049228|1|1|395937-397372|CRT
GTATTTCCCGCACATGCGGGGGTGATCC	CAATTGAAAGAGAAAAGCGACGGCGAAGACTGG
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGTCAAAAGCCAGTCACCTCTGCAGCAGTA
GTATTTCCCGCACATGCGGGGGTGATCC	TCTGCGCTGCACCTTTCGGGTTTCGGTAAGCTA
GTATTTCCCGCACATGCGGGGGTGATCC	CGGCTGTTTATTTTTTTATTCTTAACTCTTTTA
GTATTTCCCGCACATGCGGGGGTGATCC	TTGTAAAGAGAAAAGGAAAGAGGAAAAGAAAATG
GTATTTCCCGCACATGCGGGGGTGATCC	TAATTCAAATCCTTCTTTTAACAATTTACACATAA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCGAGCTAGAAGATAAAATCAATGAATTTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	CTCATTTTGTGTATCTTTTTTAGTTTCTTCAAG
GTATTTCCCGCACATGCGGGGGTGATCC	TGGTTTTTAGCTAAGGGCAACAAAGATATTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTCTAATTTCGTTGTTTTCAAAATTGAATTT
GTATTTCCCGCACATGCGGGGGTGATCC	TATAGCTTGCTTGCACTGCACCTTTAGCGAGTG
GTATTTCCCGCACATGCGGGGGTGATCC	CTATGGGAAGTTTTTACTTTTCTATGTCAATGCG
GTATTTCCCGCACATGCGGGGGTGATCC	CAGCGTTATTATATAAGTATAAAGAGAAAAGGA
GTATTTCCCGCACATGCGGGGGTGATCC	TGGAAAACAACAATGCGGACTGGAAAGGCAGAT
GTATTTCCCGCACATGCGGGGGTGATCC	TCAGCAAAGTAGCAAACGTATGACGAAAACCAT
GTATTTCCCGCACATGCGGGGGTGATCC	TAGACGCACTTACGCAAAGTATGACTTACTTTT
GTATTTCCCGCACATGCGGGGGTGATCC	TACACACTATGAGCATGAGTGTGATTAGCTTCA
GTATTTCCCGCACATGCGGGGGTGATCC	CGATCAATTTTTGGAAAGCGGGGAGTATATAGG
GTATTTCCCGCACATGCGGGGGTGATCC	TGCTTGTGCTAAACCTTGTACATTTTTCATCAA
GTATTTCCCGCACATGCGGGGGTGATCC	TACTTGCGTCGGTATGTAGCCCGTTCCAGTTAT
GTATTTCCCGCACATGCGGGGGTGATCC	TGACCAACTAAAAGATTTAGCAGGCATGGTAAA
GTATTTCCCGCACATGCGGGGGTGATCC	GCTACCGAGGGAGTAAATTATGTAAACCCGTCA
GTATTTCCCGCACATGCGGGGGTGATCC	TCAACGCTTACTTCAAAGTAATAAAGTCACTTTA
GTATTTCCCGCACATGCGGGTGACGATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049228.1\|WP_102695511.1\|394982_395882_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_CP049228.1\|WP_102695513.1\|389260_390949_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_CP049228.1\|WP_006735491.1\|410873_411863_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
NZ_CP049228.1\|WP_164823917.1\|386520_389274_+\|CRISPR-associated-helicase-Cas3'	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_CP049228.1\|WP_006735522.1\|393387_394047_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_CP049228.1\|WP_006728840.1\|385013_385793_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP049228.1\|WP_102695509.1\|398538_399486_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223566
NZ_CP049228.1\|WP_006735507.1\|392641_393379_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187886
NZ_CP049228.1\|WP_006733185.1\|390958_391546_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NZ_CP049228.1\|WP_006736801.1\|412025_413120_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NZ_CP049228.1\|WP_009310570.1\|397553_397739_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049228.1\|WP_006734896.1\|391548_392625_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_CP049228.1\|WP_006731167.1\|406858_409453_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|237515
NZ_CP049228.1\|WP_164823918.1\|409618_410818_+\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP049228.1\|WP_006732689.1\|413984_414803_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP049228.1\|WP_102695510.1\|397866_398511_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182775
NZ_CP049228.1\|WP_006734889.1\|385792_386401_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|377811
NZ_CP049228.1\|WP_006729005.1\|405155_406529_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP049228.1\|WP_006732691.1\|413119_413983_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP049228.1\|WP_102695512.1\|394043_394982_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693

Protein	Function_ID	Function_description	E-value
NZ_CP049228.1\|WP_102695511.1\|394982_395882_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	2.99018e-45
NZ_CP049228.1\|WP_102695513.1\|389260_390949_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.60772e-86
NZ_CP049228.1\|WP_006735491.1\|410873_411863_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	1.84881e-178
NZ_CP049228.1\|WP_164823917.1\|386520_389274_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.15619e-94
NZ_CP049228.1\|WP_006735522.1\|393387_394047_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.50803e-57
NZ_CP049228.1\|WP_006728840.1\|385013_385793_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.03299e-109
NZ_CP049228.1\|WP_102695509.1\|398538_399486_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	1.0362e-50
NZ_CP049228.1\|WP_006735507.1\|392641_393379_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.71205e-46
NZ_CP049228.1\|WP_006733185.1\|390958_391546_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	7.09982e-30
NZ_CP049228.1\|WP_006736801.1\|412025_413120_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	4.57404e-131
NZ_CP049228.1\|WP_102695510.1\|397866_398511_-\|hypothetical-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	8.31325e-66
NZ_CP049228.1\|WP_006734896.1\|391548_392625_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	2.95314e-157
NZ_CP049228.1\|WP_006731167.1\|406858_409453_+\|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase	gnl\|CDD\|237515	PRK13805, PRK13805, bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional.	0
NZ_CP049228.1\|WP_164823918.1\|409618_410818_+\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP049228.1\|WP_006732689.1\|413984_414803_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.68914e-62
NZ_CP049228.1\|WP_006734889.1\|385792_386401_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|377811	pfam07314, DUF1461, Protein of unknown function (DUF1461). This family contains a number of hypothetical bacterial proteins of unknown function approximately 200 residues long. These are possibly integral membrane proteins.	3.54258e-29
NZ_CP049228.1\|WP_006729005.1\|405155_406529_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	6.30429e-150
NZ_CP049228.1\|WP_006732691.1\|413119_413983_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	8.46202e-65
NZ_CP049228.1\|WP_102695512.1\|394043_394982_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	4.31139e-133

>NZ_CP049228.1|WP_102695511.1|394982_395882_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MPLTVITLKKSPPSLRGDLTKWMQEISTGVYVGNFNSKIRSELWKRVIENVGMGTATMSYACRNEIGYNFEIHNSNKIPIDFDGIPLVMTPAIENSCSTEYKYGFSNAAKILKAKRYKGNISSIDTNTKPYVIIDLETTGLDYINNNIIEIGAIKIAKNIEEYSCIVKQNITLPNAIKILTGISDAELKNGKDESVAIKELCTFIGDKALVGYNVNFDIRFINEALKRNGQSQLTNKVYDVMKYVKRDKMFLKNYKLDTVLSEYGINIKVPHRAIEDVKIIRLLISKLDGLTNKLKIQK
>NZ_CP049228.1|WP_102695512.1|394043_394982_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MSKIIGAKKTELNELPRISDRVSFIYVEHAKINRIDSSITVSDYRGVVTIPCAIIGVLMLGPGTDISHRAIEILGDTGTSVIWVGERGVRYYAHGQSLSHSTKLLEKQAKLVSNTKTRLDVARKMYAMRFKNEDVSKLTMQQLRGREGARIRRLYREQATKFKVEWNRRDYKIHDFESSNVVNQALSAANVSLYGVCHSVIVALGMSPGLGFVHTGHDKSFVYDIADLYKAELTIPLAFSLAAEAKDNDDIGQLARLALRDKMLDGRVMQKIVTDLQYLMDISEDEKINADIIELWDDKGENKKYGINYTEE
>NZ_CP049228.1|WP_006735522.1|393387_394047_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRVEIDLYNRKKIRELKHIGCYHGWIEDAFPDERDKPKSARSRKLWRIDNINDKCYLLILSESKPDFKKLEKYGIQHSACTKNYDEFLNSLKEGMRAKFRIKLNTVKSYSNREVYKKRGRVAPVSMDGLNSFFIERTEKNGFFVKDDEFRIIRREEERFEHYAEDKSEETNINLVSATYEGVLTITDLEKFKQTLTKGIGRKKAYGFGFLTIIPIK
>NZ_CP049228.1|WP_006735507.1|392641_393379_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKTILLKLKGPMQSWGTSSHFETRTTDYYPSKSAVIGIIAASFGYKRDNDEKIQKLNELNFAIRIDQPGVLAKDYHIATKYKVNIDKKYKISVAFDRNYVTNRYYMEDAIFVVAISHADDQWIDSIYHALQNPYFTPFMGRRSCPLPADFIITVTNKDALDALQNLEWQAAKWYKRKHQNYCADIYADKDLNLQGIATTRNDRVVSFSQKERKFGPRFETRTSKDFTNGRNDASNSNSLDFYESI
>NZ_CP049228.1|WP_006734896.1|391548_392625_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTNSINQRLFLDIHAIQTVPPSNINRDDTGSPKTAQYGGVTRARVSSQSWKRAIRKYFYDKGDTQNIGIRSCDIVKYIAKKIVDKDNSISVEDAITLVEKTLNAAKLSTKDQKLKALFFISNNQADKFAQACLDKKTDKTELQEILKTDTSIDIALFGRMLADDPSLNEDASSQVAHAISTHAIESEFDFYTAVDDLAPEDNAGAGMLGTLEYDSSTLYRYANIALHDFYKQLGDKEEVIDAVKLFVEAFVKSMPTGKINSFANQTLPQAVVVSLRSDRPINLVSAFEEPVKSENGYVDKSIQKLFAEYVKYEKILDKPIFTDYLLLDDTLEVKSIGKSTQNLDELLSDLKESINVNL
>NZ_CP049228.1|WP_006733185.1|390958_391546_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MEGSNVYNVTAKILRKINQTKDTSSTRALFANIRNSINKSSSNNLDALAFVFNNMPEEYIGFGKELSDYEQAILTAIQMYALHQQSNEKSVLKIEYNEGEKRQNLGDALSTLRGSDNKSIDRRFNAMILSSNYLQLQNHLRQFIKLLKAKSDAKVDYASVADDLFWFLKNQKDGVKIKWSRSYYKFRKVNDKGEN
>NZ_CP049228.1|WP_102695513.1|389260_390949_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSDYNLIDEPWISVVVDYKGTTKLVGLKEFFEHAHEYIALAGDMPTQDFAVMRFLLAILHTVFSRYDAHGEPYEMIELNDRMQQIEKVDLEDEEDYEDALMETWKDLWNAKKFPEIVVKYLDAWHDRFYLFDDKYPFYQVTKEEIDTSKISKASPSKILGKNINRLISESGNKIALFSPKYDANNNKGLLTYDELTRWLITFQSYTGLSDKVIFGNEKYKASKGWLFDLGGVYLSSDNLYQTLILNLRLINRSNVNYNYSVQKPCWENAPSKLVEKAIRSSCIDNIAELYTTWSRAIYFNKFNMDDVFQMEIVKLPDIKHEDMFLEPMTLWKYNNVGDNKGKFTPRKHQLNKSLWRSFGLMTKFEEVGEVNAKIPKRKPGIIEWLNDIDESIKNQHIKINAISMEDDGNATSWVPINEVEDKLDIGEFIVNDLQKNGWVDRINNIVDRTKDIIEKNYRAFLNDIAKIRGIESGAFTSSSIESMYFKIDKPFRDWLTNINYDDNKDEKEQIWNKELKNLVIRQAKIIIEQASPKDFTGIIENDSVKNIVTAYNNLMSNINKKL
>NZ_CP049228.1|WP_164823917.1|386520_389274_+|CRISPR-associated-helicase-Cas3'
MEKYLWAKKNLVDGVPMWLPLTVHLNDTAEICGLLYEHWLSDGVKYFLEKAIISDVENKEDLLKNLCKFLGAVHDIGKATPIFQTKQSFCGDRELDNLINEKLRQAGFKEVDKYIAERKNNVLHNISGQYFLNKCFKVNLCVANIIGAHHGRPISQEQVMSACESFTSSLYQDDNEKSSLAMFWKEKQRGIFDWAMEACNFSCVEDLPLISQPGQVILSGLLIMADWIASNEKYFPLIPIDTDTVDPDRVEKGFTKWYRDRAETWEPESYCNDIYQKRFGFEPREVQKKVSDIISKIDNPGIVIMEAPMGIGKTETALVAVEELAKKTNRTGIFFGLPTQATSNGIFSRVEDWLKHCEGEKSIRLIHGKAQLNDQFANLPKSRNIHSEDSVGVNEWFAGRKVAILDDFTVGTVDQVLLAALKQKHLMLRHLGFANKVVVIDEVHAYDAYMSVYLYQALMWLGAYGVPVILLSATLPISKRNELLKQYMVGAGYRFKKLDKPQDFDNNENYPLLTYNDGEKINQFSDFSQECGTDYKVIPKAKDESENIVDLINELTTNVGIVGVILNTVKKSQKFAEQCVNAFGEKNVELLHSSFIATDRYKKEQELINTIGKNGKRPKFKIIIGTQVIEQSLDIDFDVLITDLAPMDLLLQRMGRLHRHSDTKRPENLKKPQVYILNCGNYDFDEASTYVYAKYLLFRTEYFLPNKVNLPNDISHLVQLVYSDNALNLSDDSLKKDYTTYQGKYNADIDKKEQQAEVYRLVKPLKKISQEKNLSDWIKNSNHSAELSDVNAYAQVRDSADSVEVIALKKCEGGYEFFDKSGKLDPTDNKTAMEIAKRTIQLPSATYYGIGIDEVIKELEKYYLKHFQDWNQQSWLKGSLAIIFDQNDEFSLLNKKILRYNNKYGLKVVTEDINERL
>NZ_CP049228.1|WP_006734889.1|385792_386401_+|TIGR01906-family-membrane-protein
MKNKLSIVIYNFVAAILLSLWGTILLSWPILLVMMIAQRTNKLIHLSLFGALKNYSQLMSYLINPVFDKLQMSDLQSSLNGLIHFKDCKNLFSIALMLGCIWLFIFLYFEIWKKKKIVSLPHSYTICLLLLPLIVVPFSMGNFTNLFILFHRAMFTNNNWLFNPDTDPIILILTEEFFAACSATFLLIYELYFVRLLIKKGR
>NZ_CP049228.1|WP_006728840.1|385013_385793_+|TIGR01457-family-HAD-type-hydrolase
MNKQYGCYLIDLDGTIYRGEKTIQSGVDFVNRLNEKKIPYLFLTNNTTRTPEMIVAKLASHGVITDVDHVYTPIMATVSYLLEHNPGTDAIPVYIIGQIGLWKGLLAEDRIVLDNNNPKYVIVGMDTDLTYKKICIATNAIRKGAEFIGTNSDHVLPSGDKLLPGNGSQCAMIAVASDQKPFFIGKPSAVIVNYALKKIKKNIEESLIVGDNYETDIMAGINCRMDSLLTLTGVTTKKQLAEEKIQPTYVLNNLDEWQL
>NZ_CP049228.1|WP_009310570.1|397553_397739_+|hypothetical-protein
MGRELMGLASCDDDRKAIINFTIVAAKYFNDQVTVEKINDSLKEHSQAPLTEEEKKFYGVK
>NZ_CP049228.1|WP_102695510.1|397866_398511_-|hypothetical-protein
MNLLDFILNIDKHLITIVNSCGDWTYLILFLIVFMETGLVVFPFLPGDSLIFATIAMAASPKYHLDLIICYIIFIIAAICGDSINYELGKWSELQSNKFKWFNKLINPQKKKAAEDFFEKHGGITIVIGRFIPIIRTFVPFVSGASKMHYRTFVIYNIVGAFLWVSLFSICGFLFGNIPAVQHHFSLLIIAIIAISILPIIILSIKNKLTKNSK
>NZ_CP049228.1|WP_102695509.1|398538_399486_-|NAD(P)/FAD-dependent-oxidoreductase
MEYYDLAIVGAGPVGLFATKFANLHGLKTITFEALADCGGQINRLFPNKKIKDIPGYNSIIGHQLVDKLKEGIDSKIITNYKVQEIIQKGSEIIIDNNYQAKTLLITSGMGAFTPKKLPLPIDSSCEKHIHYFVKNADHFQDKNVAIFGGGDSALDWAMQMADKCKIVIIHRRDQFRGMESTLKFLHQHNNVRFLTPYLPQKIIWQNNQLNILLKKLGTEEMEEIKCDEAVIAFGFKSDNLLLKKWGLNLETGHVKVNSQMQSNIENIYAAGDACIYDGRVPMMALGFGEAQIAIMSIMNHLFPEKKLTIHLSSH
>NZ_CP049228.1|WP_006729005.1|405155_406529_-|amino-acid-permease
MKQKKSHSSKDISMKRSLTNTHIQLIALGGTIGTGLFLGVGNSIELAGPAVILIYTLVGFFLFLLMRALGELILSDLNKNTYIDFITQYLGKVIGTVTGYLYWFSWLSLGMAELTALGLYFRYWWHDLPLWLPGSITLIILLMINLISAKVFGNMEFSFAIIKILTIVAFVLLVFYLLITNGSTKLYGAISFSNLFKDGGFFAKGANGFFSGFQMVIFSFIGVELIGLTAAEAQDPKKTIVKAINELPVRIILFYVLAILAILLVIPWKQVAINDSPFVQALGATGIKNAACIINFVVISAAISSTNTFIYSGGRLLFSLNYHGQSNFAKCMGQLNKRQLPENALLFSTLLIGIAPIMNLFLENAFHFIAATSTSMFLIIWSIMIWAHIRYRKQTPEQQLHNFRMPLYPYTDYLVLGFFITMIGLLLWVPKDRIPMISALVIFSILILSIKFIKKIK
>NZ_CP049228.1|WP_006731167.1|406858_409453_+|bifunctional-acetaldehyde-CoA/alcohol-dehydrogenase
MAKEIASATKKEQIDVQAMIDSYVVQAHVALDKMANFSQEQVDKICEAIAKVGEQNSYLLAKMAVEETGRGIVEDKTIKNMFASENIWNSLRHEKTVGIISEDPERQLIKIAEPVGVIAGVTPVTNPTSTVIFKSMIALKTRNTIIFGFHPQAQKCCVKTAELIREAAIKAGAPDNCIQWIEYPSIEATNALMTHPNIQTILATGGPGMVKAAYSSGKPALGVGPGNGPAYIEKTANYQRAAYDIILSKTFDNGMVCASENSVVIDKDIYDKVKKEFEAWNCYFLNKDEIKKFETTFIDPRRGTVAGPIAGKSAYEIGKLCGVDVPEDTKVIIAEYSGVGKEYPLSAEKLSPVFTMYKVSGADEAFKICKDLLSYGGRGHTVGIHTENKELIKKFALAMSACRILVNTPAALGGIGDLYNNMLPSMTLGTGSYGANSMSHNISAADLLNIKTVAMRRDNMQWIKVPKKTYFEHNAANYLKHMPDVEKFFIVTDETVAGKYANQITDIISQRLGKKSYEVFQAVKEHPTTDVILDGVHRMNIFKPDAIVALGGGSVMDAAKIMRLFYENPDMTLEDSYQKFIDIRKRVVRFPKTNMVQLVCIPTTSGTGSEVSPFAIIKDTQTGIKHTLCDYSLNPDVAIVDDNFVETLPAKLVANSGMEALAHAMESYVSTMATDFTRGWSMEAIKLIFANLEKSYKGDQAARSKMHNASTLAGMAYANAFLGVGHAIAHTLGSTFNIPSGLSDAITMPYVIKFNAQRPRKLPIRPHYSVFRADKDYAEIARSLGIQGKNDQELVDGLINKFVELAKSINMTLNLKDNGVSEADFNNKVEQLAVEAYGDQNIVTNPSAPLIKQIEQLMKKIYVG
>NZ_CP049228.1|WP_164823918.1|409618_410818_+|acetate-kinase
MKKILAINSGSSSFKYKLFNYPSEEVVAQGQAQRIGLAGSTFSLKLADGSKYESEIKIPDHKTAIQLLLTWLPKYNVINDLKEIAGIGHRVVAGGEIFSESALIDKEKLQQIYDLSDYAPLHNPYEADGIRDFMQLLPGVPQVAVFDTSFHHTLDPVHYLYSLPYKYYEKYRARKYGAHGTSVRYVSHRAAELLNKPLNTLKMIVCHLGNGASITAIKDGKSYDTSMGFSPVAGITMSTRSGDIDPSVLQYVMKKENISDFNKMINILNNKSGILGISDYSPDMRDIRKRAAAGDVKAKLAKDIFVNRIIKYIGSYYVDMGGLDALVFTAGIGENESLYRQAIVDKLSVLGLKIDEKTNSVNGEKVISAVDSKAKILIIPTNEELVIARDVVRLAKINK
>NZ_CP049228.1|WP_006735491.1|410873_411863_-|UDP-glucose-4-epimerase-GalE
MNILVIGGAGYIGSHAVRKLLDSGYHVVVLDNLITGHRKAIDPRAKFYQVDLLNTFLVSKILRDEKIDAIMHFAAYSLVSESVQKPLLYYQNNITGMISLLNAMNDAKVKYLIFSSSAATYGIPEKLPITEEAPLKPINPYGETKMMMEKMMLWADKANNIKSIALRYFNVAGAANDGTIGEDHRTESHLIPNILKCADSHDKIFTIYGNDYQTLDGTNVRDYVEIEDLIDAHILALQHLIKTNLSDVFNLGTAHGYSNLEILECAKRITATDIPYKFGPRRGGDPDSLVADSTKARTILGWQPKHENIDNIIASAWKWHQKHPNGFED
>NZ_CP049228.1|WP_006736801.1|412025_413120_+|ABC-transporter-ATP-binding-protein
MNEDNFIQIKNLKMVYENGYQAISDISFTVKKGELVCLLGPSGCGKTTTLNMVAGLLNPTGGDILVDGKSVLNVAPKDRNIGYVFQNYALYPHMTVLQNVMFPMTVGKNKKSKEEAKQIAERFMRLTHIEEYANQKPGKLSGGQQQRVSIARALVQQPKILLMDEPLSNLDARLRLKIREEIRALVKKVGITTLFVTHDQEEALSIGDKIILFNEGVIQQDAASYEIYLNPANQFVANFIGNPVVDNFNVEVSDGKVKGDGFEIPLSAFDSDRFKKNITDGVYTLSLRPENVFPVDNQADGFFTCKIDDIELIGRERILKFTINGLGQRSLVKVEANVEPGDEICFGLNLDRAFIFDNNGERIY
>NZ_CP049228.1|WP_006732691.1|413119_413983_+|sugar-ABC-transporter-permease
MENNQKKAWLFLLPAIISVTIFSIWPIIRAFIISFQGGPLICLNFNGIENYKYIFADTDFWNSLINTAIYAFMTVPIALAIALALAWFVFSKIKHQSFFEAMFFMPYVTSTIATGIVFRYIFNGKYGLLDFVLKMLHLPAPDWLDDPSMSLISLIIFGIWSSLAFNIVILIGALRNIDPNYYVLADMYGANESEKFWRITIPQLFPTLAFLLTVNLIGAFKVYTQVFALFNGSAGQGNSAITSVFYIYNKFQVANTPGVAMAATVCLFLFILFITCLQRKLMKRVNS
>NZ_CP049228.1|WP_006732689.1|413984_414803_+|carbohydrate-ABC-transporter-permease
MKKIKTVFIYIFVTFFAIITVFPFIYMIFGGLMTYEETTRIPPTFVPGSFKISNYLAVFNQAPFARYFFNTFVTATTTTVVSLFTSILGAFAMANLKFKGKGLIKIILISLLMVPGEAIIFTNYTTIMSMGLINTYIGLVIPFLTSIFYMYYLQSYFKSITPTVYKAAMIDGASDWEYIWRILVPMSKSGLITVALLSFISGWNAFLWPLLVTNESDMRLLNNGLAAFATEAGSQTQLQLAAATLIVLPILIVYFVFRKQIIRGVVNHEFKA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049228_1	1.4\|396148\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396148-396180	33	NZ_CP007677	Staphylococcus aureus strain HUV05 plasmid pHUV05-01, complete sequence	3139-3171	7	0.788
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MK784777	Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence	83714-83747	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP012368	Enterococcus durans strain KLDS 6.0933 plasmid unnamed 2, complete sequence	10683-10716	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP012386	Enterococcus durans strain KLDS 6.0930 plasmid unnamed 2, complete sequence	23179-23212	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP032740	Enterococcus casseliflavus strain EC-369 plasmid pEC369, complete sequence	26854-26887	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MH830362	Enterococcus faecalis plasmid p4, complete sequence	3146-3179	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MH830362	Enterococcus faecalis plasmid p4, complete sequence	53851-53884	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP040905	Enterococcus faecium strain N56454 plasmid unnamed, complete sequence	120962-120995	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_AP022823	Enterococcus saigonensis strain VE80 plasmid pVE80-1, complete sequence	63227-63260	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_LR135352	Enterococcus faecium isolate E8014 plasmid 2	177282-177315	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP049776	Enterococcus faecalis strain ES-1 plasmid unnamed1, complete sequence	78706-78739	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP028836	Enterococcus faecalis strain FC plasmid unnamed1, complete sequence	44976-45009	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_LR135172	Enterococcus faecium isolate E4227 plasmid 3	44746-44779	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	798-831	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	7050-7083	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	114804-114837	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_MG674582	Enterococcus faecium strain HL1 plasmid pVEF4_A, complete sequence	41884-41917	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MK465703	Enterococcus faecium strain E505 plasmid pE505-1, complete sequence	39042-39075	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MK465704	Enterococcus faecium strain E211 plasmid pE211-2, complete sequence	11574-11607	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_KX810026	Enterococcus faecium strain Efm0038 plasmid pJEG043, complete sequence	26501-26534	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_KX579977	Enterococcus faecalis strain EF123 plasmid pEF123, complete sequence	444-477	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MK798157	Enterococcus hirae strain fas4 plasmid pfas4-1, complete sequence	6146-6179	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_014475	Enterococcus faecalis plasmid pWZ1668, complete sequence	33940-33973	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP030934	Enterococcus gilvus strain CR1 plasmid pCR1B, complete sequence	58231-58264	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP020486	Enterococcus faecium strain CFSAN059070 plasmid unnamed2, complete sequence	33325-33358	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_014726	Enterococcus faecalis plasmid pTW9, complete sequence	82406-82439	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP027519	Enterococcus faecium strain AUSMDU00004024 plasmid unnamed2, complete sequence	2768-2801	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_LR135784	Enterococcus faecium isolate E4239 plasmid 3	8166-8199	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_LR135430	Enterococcus faecium isolate E8927 plasmid 3	3714-3747	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_LR132068	Enterococcus faecium isolate E0139 plasmid 2	61282-61315	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_008445	Enterococcus faecalis RE25 plasmid pRE25, complete sequence	17025-17058	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP038866	Vagococcus sp. CF-49 plasmid punnamed1, complete sequence	24683-24716	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_AP018541	Enterococcus faecalis strain KUB3006 plasmid pKUB3006-3, complete sequence	11664-11697	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_019284	Enterococcus faecalis plasmid pWZ7140, complete sequence	32852-32885	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_019213	Enterococcus faecalis plasmid pWZ909, complete sequence	28177-28210	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_010540	Lactococcus garvieae plasmid pKL0018 DNA, complete sequence	9453-9486	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_013514	Enterococcus faecalis plasmid pAMbeta1, complete sequence	10448-10481	7	0.794
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	MK784778	Enterococcus faecalis strain E508 plasmid pE508-2, complete sequence	35767-35800	7	0.794
NZ_CP049228_1	1.8\|396395\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396395-396427	33	NZ_CP017256	Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence	22865-22897	7	0.788
NZ_CP049228_1	1.10\|396517\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396517-396549	33	NZ_CP013798	Piscirickettsia salmonis strain AY6532B plasmid p2PS9, complete sequence	527-559	7	0.788
NZ_CP049228_1	1.21\|397189\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397189-397221	33	MN693811	Marine virus AFVG_250M463, complete genome	5399-5431	7	0.788
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	11909-11942	8	0.765
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	1595-1628	8	0.765
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NC_014825	Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence	320920-320953	8	0.765
NZ_CP049228_1	1.8\|396395\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396395-396427	33	MN693143	Marine virus AFVG_25M149, complete genome	13258-13290	8	0.758
NZ_CP049228_1	1.8\|396395\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396395-396427	33	NZ_CP014325	Borrelia anserina Es isolate UTHSCSA plasmid lpA89, complete sequence	66315-66347	8	0.758
NZ_CP049228_1	1.13\|396701\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396701-396733	33	NZ_CP049224	Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence	58135-58167	8	0.758
NZ_CP049228_1	1.4\|396148\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396148-396180	33	KT997846	Uncultured Mediterranean phage uvDeep1-CGR2-KM23-C896, complete genome	24476-24508	9	0.727
NZ_CP049228_1	1.4\|396148\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396148-396180	33	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	356938-356970	9	0.727
NZ_CP049228_1	1.4\|396148\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396148-396180	33	KY554777	Lactococcus phage LW81, complete genome	93614-93646	9	0.727
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	24848-24881	9	0.735
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	13502-13535	9	0.735
NZ_CP049228_1	1.6\|396271\|35\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396271-396305	35	NZ_CP014857	Lysinibacillus sphaericus III(3)7 plasmid, complete sequence	64675-64709	9	0.743
NZ_CP049228_1	1.6\|396271\|35\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396271-396305	35	NZ_CP014644	Lysinibacillus sphaericus strain OT4b.25 plasmid unnamed, complete sequence	34566-34600	9	0.743
NZ_CP049228_1	1.7\|396334\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396334-396366	33	AJ609634	Bacteriophage EJ-1 proviral DNA, complete genome	2370-2402	9	0.727
NZ_CP049228_1	1.7\|396334\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396334-396366	33	NC_005294	Streptococcus prophage EJ-1, complete genome	2370-2402	9	0.727
NZ_CP049228_1	1.7\|396334\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396334-396366	33	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	320982-321014	9	0.727
NZ_CP049228_1	1.7\|396334\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396334-396366	33	NZ_CP033047	Virgibacillus sp. Bac332 plasmid unnamed, complete sequence	58145-58177	9	0.727
NZ_CP049228_1	1.7\|396334\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396334-396366	33	NC_010180	Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence	124902-124934	9	0.727
NZ_CP049228_1	1.8\|396395\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396395-396427	33	NZ_CP041067	Bacillus megaterium strain KNU-01 plasmid pKNU_01_3, complete sequence	32228-32260	9	0.727
NZ_CP049228_1	1.14\|396762\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396762-396794	33	MH248138	Erwinia phage vB_EamM_Alexandra, complete genome	237366-237398	9	0.727
NZ_CP049228_1	1.19\|397067\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397067-397099	33	NC_022877	Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence	134661-134693	9	0.727
NZ_CP049228_1	1.19\|397067\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397067-397099	33	NC_022882	Bacillus thuringiensis YBT-1518 plasmid pBMB0233, complete sequence	97448-97480	9	0.727
NZ_CP049228_1	1.21\|397189\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397189-397221	33	MN693872	Marine virus AFVG_250M911, complete genome	64918-64950	9	0.727
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	19952-19985	10	0.706
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	24234-24267	10	0.706
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP045289	Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence	4601-4634	10	0.706
NZ_CP049228_1	1.19\|397067\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397067-397099	33	NZ_CP043553	Francisella marina strain E95-16 plasmid pE95_16_1, complete sequence	3958-3990	10	0.697
NZ_CP049228_1	1.19\|397067\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	397067-397099	33	NZ_CP043551	Francisella marina strain E103-15 plasmid pE103_15_1, complete sequence	3212-3244	10	0.697
NZ_CP049228_1	1.23\|397311\|34\|NZ_CP049228\|CRISPRCasFinder,CRT	397311-397344	34	NZ_CP009417	Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence	544649-544682	10	0.706
NZ_CP049228_1	1.4\|396148\|33\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396148-396180	33	KX905163	Clostridioides phage phiSemix9P1, complete genome	50320-50352	11	0.667
NZ_CP049228_1	1.5\|396209\|34\|NZ_CP049228\|PILER-CR,CRISPRCasFinder,CRT	396209-396242	34	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	1230861-1230894	11	0.676

1. spacer 1.4|396148|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007677 (Staphylococcus aureus strain HUV05 plasmid pHUV05-01, complete sequence) position: , mismatch: 7, identity: 0.788

cggctgtttatttttttattcttaactctttta	CRISPR spacer
agtcatgttattttttttttcttaattctttta	Protospacer
 * *   ********** *******.*******

2. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MK784777 (Enterococcus faecalis strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

3. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012368 (Enterococcus durans strain KLDS 6.0933 plasmid unnamed 2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

4. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012386 (Enterococcus durans strain KLDS 6.0930 plasmid unnamed 2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

5. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032740 (Enterococcus casseliflavus strain EC-369 plasmid pEC369, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

6. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

7. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

8. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040905 (Enterococcus faecium strain N56454 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

9. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022823 (Enterococcus saigonensis strain VE80 plasmid pVE80-1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

10. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135352 (Enterococcus faecium isolate E8014 plasmid 2) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

11. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049776 (Enterococcus faecalis strain ES-1 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

12. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028836 (Enterococcus faecalis strain FC plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

13. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135172 (Enterococcus faecium isolate E4227 plasmid 3) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

14. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

15. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

16. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

17. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG674582 (Enterococcus faecium strain HL1 plasmid pVEF4_A, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

18. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MK465703 (Enterococcus faecium strain E505 plasmid pE505-1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

19. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MK465704 (Enterococcus faecium strain E211 plasmid pE211-2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

20. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX810026 (Enterococcus faecium strain Efm0038 plasmid pJEG043, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

21. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX579977 (Enterococcus faecalis strain EF123 plasmid pEF123, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

22. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MK798157 (Enterococcus hirae strain fas4 plasmid pfas4-1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

23. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_014475 (Enterococcus faecalis plasmid pWZ1668, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

24. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030934 (Enterococcus gilvus strain CR1 plasmid pCR1B, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

25. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020486 (Enterococcus faecium strain CFSAN059070 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

26. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_014726 (Enterococcus faecalis plasmid pTW9, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

27. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027519 (Enterococcus faecium strain AUSMDU00004024 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

28. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135784 (Enterococcus faecium isolate E4239 plasmid 3) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

29. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR135430 (Enterococcus faecium isolate E8927 plasmid 3) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

30. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR132068 (Enterococcus faecium isolate E0139 plasmid 2) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

31. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_008445 (Enterococcus faecalis RE25 plasmid pRE25, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

32. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038866 (Vagococcus sp. CF-49 plasmid punnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

33. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018541 (Enterococcus faecalis strain KUB3006 plasmid pKUB3006-3, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

34. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_019284 (Enterococcus faecalis plasmid pWZ7140, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

35. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_019213 (Enterococcus faecalis plasmid pWZ909, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

36. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_010540 (Lactococcus garvieae plasmid pKL0018 DNA, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

37. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_013514 (Enterococcus faecalis plasmid pAMbeta1, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaa----agagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaatcaaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    **    *.*.*****.******************

38. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MK784778 (Enterococcus faecalis strain E508 plasmid pE508-2, complete sequence) position: , mismatch: 7, identity: 0.794

ttgtaaa----gagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
----aaaaatcaaaaaaagaaaagaggaaaagaaaatg	Protospacer
    ***    .*.*****.******************

39. spacer 1.8|396395|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017256 (Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence) position: , mismatch: 7, identity: 0.788

ctcattttgtgtatcttttttagtttcttcaag	CRISPR spacer
aacattttttgtatcttttttagttactttatc	Protospacer
  ****** **************** ***.*

40. spacer 1.10|396517|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013798 (Piscirickettsia salmonis strain AY6532B plasmid p2PS9, complete sequence) position: , mismatch: 7, identity: 0.788

-tgctctaatttcgttgttttcaaaattgaattt	CRISPR spacer
atgctgc-atctcgttgttttcaaaaatgaatag	Protospacer
 **** . **.*************** *****

41. spacer 1.21|397189|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MN693811 (Marine virus AFVG_250M463, complete genome) position: , mismatch: 7, identity: 0.788

tgaccaac-taaaagatttagcaggcatggtaaa	CRISPR spacer
-gtggaacgtaaaagatttaacaggcatgttaat	Protospacer
 *   *** ***********.******** ***

42. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
agaaagagaaaaaaggaaaaaggaaaagaaaaag	Protospacer
  . *.***.*********.************ *

43. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
aggaagaaagaaaaggaaggaagaaaagaaaagg	Protospacer
  * *.*.**********.**.********** *

44. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_014825 (Ruminococcus albus 7 = DSM 20455 plasmid pRUMAL02, complete sequence) position: , mismatch: 8, identity: 0.765

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
atggtccgataaaaagaaagaggaaaagaaaaag	Protospacer
 **    ** ****.***************** *

45. spacer 1.8|396395|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MN693143 (Marine virus AFVG_25M149, complete genome) position: , mismatch: 8, identity: 0.758

ctcattttgtgtatcttttttagtttcttcaag	CRISPR spacer
aaccgtttgtttatcttgtttagtttcttcagt	Protospacer
  *  ***** ****** *************.

46. spacer 1.8|396395|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014325 (Borrelia anserina Es isolate UTHSCSA plasmid lpA89, complete sequence) position: , mismatch: 8, identity: 0.758

ctcattttgtgtatcttttttagtttcttcaag	CRISPR spacer
ttcgtaaaatgtatcttttttaatttgttcaag	Protospacer
.**.*   .*************.*** ******

47. spacer 1.13|396701|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049224 (Lactobacillus iners strain C0094A1 plasmid pC0094A1, complete sequence) position: , mismatch: 8, identity: 0.758

cagcgttattatataagtataaagagaaaagga	CRISPR spacer
aaaggttgatatataagtataaagagaaaaaat	Protospacer
 *. ***. *********************..

48. spacer 1.4|396148|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to KT997846 (Uncultured Mediterranean phage uvDeep1-CGR2-KM23-C896, complete genome) position: , mismatch: 9, identity: 0.727

cggctgtttatttttttattcttaactctttta	CRISPR spacer
aataaatatatttttttattcttaactgcttta	Protospacer
 .   .* ******************* .****

49. spacer 1.4|396148|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.727

cggctgtttatttttttattcttaactctttta	CRISPR spacer
ttcttttctatttttttaattttaactcttttt	Protospacer
.  .* *.********** *.***********

50. spacer 1.4|396148|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to KY554777 (Lactococcus phage LW81, complete genome) position: , mismatch: 9, identity: 0.727

cggctgtttatttttttattcttaactctttta	CRISPR spacer
tatctcgatatttttttattttaaactcttttt	Protospacer
.. **   ************.* *********

51. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 9, identity: 0.735

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
aaaggaagagaaaaggaaaaaggaaaaggaacag	Protospacer
  . .**************.********.**  *

52. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 9, identity: 0.735

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
aaaaagaaagaaaaagaaaaaggaaaagaaaaag	Protospacer
  . *.*.******.****.************ *

53. spacer 1.6|396271|35|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014857 (Lysinibacillus sphaericus III(3)7 plasmid, complete sequence) position: , mismatch: 9, identity: 0.743

taattcaaatccttcttttaacaatttacacataa	CRISPR spacer
ccattcaaatccttcttttaataatttatctagcg	Protospacer
. *******************.******. .*  .

54. spacer 1.6|396271|35|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014644 (Lysinibacillus sphaericus strain OT4b.25 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

taattcaaatccttcttttaacaatttacacataa	CRISPR spacer
ccattcaaatccttcttttaataatttatctagcg	Protospacer
. *******************.******. .*  .

55. spacer 1.7|396334|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to AJ609634 (Bacteriophage EJ-1 proviral DNA, complete genome) position: , mismatch: 9, identity: 0.727

tgcgagctagaagataaaatcaatgaatttttt	CRISPR spacer
aaagaactagaagataaaatcaaagaattggaa	Protospacer
 . **.***************** *****

56. spacer 1.7|396334|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_005294 (Streptococcus prophage EJ-1, complete genome) position: , mismatch: 9, identity: 0.727

tgcgagctagaagataaaatcaatgaatttttt	CRISPR spacer
aaagaactagaagataaaatcaaagaattggaa	Protospacer
 . **.***************** *****

57. spacer 1.7|396334|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 9, identity: 0.727

tgcgagctagaagataaaatcaatgaatttttt	CRISPR spacer
gtaaaagaagaagttaaattcaatgaatttttt	Protospacer
   .*.  ***** **** **************

58. spacer 1.7|396334|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033047 (Virgibacillus sp. Bac332 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

tgcgagctagaagataaaatcaatgaatttttt	CRISPR spacer
ttagaactagaagaaaaaatcaatgaaagtgca	Protospacer
*  **.******** ************  * .

59. spacer 1.7|396334|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_010180 (Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence) position: , mismatch: 9, identity: 0.727

tgcgagctagaagataaaatcaatgaatttttt	CRISPR spacer
caaaatcatgaagaaaaaatcaatgaaattttt	Protospacer
.. .* *  ***** ************ *****

60. spacer 1.8|396395|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041067 (Bacillus megaterium strain KNU-01 plasmid pKNU_01_3, complete sequence) position: , mismatch: 9, identity: 0.727

ctcattttgtgtatcttttttagtttcttcaag	CRISPR spacer
gtccccaaatgcatctttttttgtttcttcaag	Protospacer
 ** ..  .**.********* ***********

61. spacer 1.14|396762|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MH248138 (Erwinia phage vB_EamM_Alexandra, complete genome) position: , mismatch: 9, identity: 0.727

tggaaaacaacaatgcggactggaaaggcagat	CRISPR spacer
tatcaaacaacaatccgaactggaaaggcgatc	Protospacer
*.  ********** **.***********.. .

62. spacer 1.19|397067|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_022877 (Bacillus thuringiensis YBT-1518 plasmid pBMB0232, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttgtgctaaaccttgtacatttttcatcaa	CRISPR spacer
tgcttgagctaaaacttgtacattactaaatcc	Protospacer
****** ****** ********** .* * .

63. spacer 1.19|397067|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NC_022882 (Bacillus thuringiensis YBT-1518 plasmid pBMB0233, complete sequence) position: , mismatch: 9, identity: 0.727

tgcttgtgctaaaccttgtacatttttcatcaa	CRISPR spacer
tgcttgagctaaaacttgtacattactaaatcc	Protospacer
****** ****** ********** .* * .

64. spacer 1.21|397189|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to MN693872 (Marine virus AFVG_250M911, complete genome) position: , mismatch: 9, identity: 0.727

tgaccaactaaaagatttagcaggcatggtaaa	CRISPR spacer
ttggaatgtaaaagatttaacaggcatgttaat	Protospacer
* .  *  ***********.******** ***

65. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 10, identity: 0.706

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
aaaagaaaagaaaaggaaagaggaaaggaaagga	Protospacer
  . .**.******************.****. .

66. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 10, identity: 0.706

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
gaaagaaaagaaaaggaaaaaggaaaagaagaaa	Protospacer
  . .**.***********.**********.* .

67. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045289 (Curtobacterium flaccumfaciens pv. flaccumfaciens strain P990 plasmid pCff2, complete sequence) position: , mismatch: 10, identity: 0.706

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
aaacaggaagaaaaggaaaagggaaaagaaaaag	Protospacer
  ..*...***********..*********** *

68. spacer 1.19|397067|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043553 (Francisella marina strain E95-16 plasmid pE95_16_1, complete sequence) position: , mismatch: 10, identity: 0.697

-----tgcttgtgctaaaccttgtacatttttcatcaa	CRISPR spacer
aaagccatt-----taaaccttttatatttttcatcaa	Protospacer
     ...*     ******** **.************

69. spacer 1.19|397067|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043551 (Francisella marina strain E103-15 plasmid pE103_15_1, complete sequence) position: , mismatch: 10, identity: 0.697

-----tgcttgtgctaaaccttgtacatttttcatcaa	CRISPR spacer
aaagccatt-----taaaccttttatatttttcatcaa	Protospacer
     ...*     ******** **.************

70. spacer 1.23|397311|34|NZ_CP049228|CRISPRCasFinder,CRT matches to NZ_CP009417 (Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tcaacgcttacttcaaagtaataaagtcacttta	CRISPR spacer
gcgtccagcacttcaaaataataaagtaactttt	Protospacer
 *. *   .********.********* *****

71. spacer 1.4|396148|33|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to KX905163 (Clostridioides phage phiSemix9P1, complete genome) position: , mismatch: 11, identity: 0.667

cggctgtttatttttttattcttaactctttta	CRISPR spacer
taaactaatatttttttattttaaactcttttt	Protospacer
... .   ************.* *********

72. spacer 1.5|396209|34|NZ_CP049228|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 11, identity: 0.676

ttgtaaagagaaaaggaaagaggaaaagaaaatg	CRISPR spacer
acagcaagagaaaagcaaagaagaaaagacagat	Protospacer
 ..  ********** *****.******* *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

330850 : 338958

Staphylococcus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006730475.1\|330850_331843_-	GMP reductase	Q4ZCY7	Staphylococcus_virus	1.7e-138	71.9
WP_006733977.1\|332034_333324_+	adenylosuccinate synthase	L7Y4J5	Megavirus	1.1e-68	37.3
WP_006737360.1\|333327_334623_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	3.5e-19	33.0
WP_006730472.1\|334736_335396_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.9e-07	25.2
WP_006735513.1\|336261_337545_-	GTPase HflX	NA	NA	NA	NA
WP_006735508.1\|337578_338229_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	2.6e-07	38.4
WP_006728884.1\|338322_338958_-	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	5.8e-28	31.9

DBSCAN-SWA_2

457418 : 484431

Lactobacillus_phage(59.09%)

capsid,portal,tail,head,terminase,integrase

attL 446403:446418|attR 463692:463707

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
446403:446418	attL	NA	NA	NA	NA
WP_164823923.1\|457418_458540_-\|integrase	site-specific integrase	Q6SEA7	Lactobacillus_prophage	7.4e-95	48.3
WP_164823924.1\|458798_459770_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	4.5e-88	52.0
WP_164823925.1\|460209_460626_-	ImmA/IrrE family metallo-endopeptidase	X2CXW8	Lactobacillus_phage	2.2e-12	39.5
WP_164823926.1\|460658_460961_-	helix-turn-helix transcriptional regulator	X2CXD8	Lactobacillus_phage	1.1e-24	60.6
WP_164823927.1\|461489_461714_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_164823928.1\|461761_462526_+	phage repressor protein/antirepressor Ant	A0A075KJT3	Lactobacillus_phage	1.3e-66	53.6
WP_164824121.1\|462580_462892_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_164823929.1\|463237_463387_+	hypothetical protein	NA	NA	NA	NA
WP_164823930.1\|463512_463989_+	hypothetical protein	A0A2P0ZLB3	Lactobacillus_phage	7.2e-23	39.9
463692:463707	attR	NA	NA	NA	NA
WP_164824122.1\|464046_464703_+	hypothetical protein	Q6SE93	Lactobacillus_prophage	1.2e-20	49.1
WP_164823931.1\|464718_465357_+	hypothetical protein	NA	NA	NA	NA
WP_164823932.1\|465353_465806_+	single-stranded DNA-binding protein	B8R683	Lactobacillus_phage	2.5e-41	57.0
WP_006737665.1\|466038_466521_+	hypothetical protein	Q20DE6	Lactobacillus_phage	1.7e-43	57.4
WP_006729801.1\|467601_467790_+	addiction module toxin, HicA family	NA	NA	NA	NA
WP_006729802.1\|467839_468235_+	antitoxin HicB	I3NLB2	Bifidobacterium_phage	1.3e-06	28.2
WP_006730906.1\|468339_468807_+	hypothetical protein	A9D9R6	Lactobacillus_prophage	3.8e-45	59.5
WP_164823933.1\|468796_470026_+\|terminase	PBSX family phage terminase large subunit	X2CYF4	Lactobacillus_phage	7.8e-138	57.2
WP_006732591.1\|470039_471470_+\|portal	phage portal protein	A0A0A1ER87	Lactobacillus_phage	2.8e-110	45.5
WP_006730975.1\|471462_473055_+\|capsid	minor capsid protein	Q6SED6	Lactobacillus_prophage	2.5e-43	32.6
WP_006730988.1\|473059_473344_+	hypothetical protein	NA	NA	NA	NA
WP_006730954.1\|473377_473869_+	hypothetical protein	NA	NA	NA	NA
WP_006730930.1\|473865_474123_+	hypothetical protein	NA	NA	NA	NA
WP_006738119.1\|474577_475183_+	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_164823934.1\|475196_476069_+	hypothetical protein	A0A0A1ELG8	Lactobacillus_phage	5.3e-80	56.0
WP_164823935.1\|476085_476490_+\|head,tail	phage head-tail connector protein	A0A097BY74	Leuconostoc_phage	1.1e-24	54.6
WP_006730902.1\|476473_476842_+	hypothetical protein	NA	NA	NA	NA
WP_006730949.1\|476841_477222_+	hypothetical protein	NA	NA	NA	NA
WP_006731470.1\|477238_477811_+\|tail	phage major tail protein, TP901-1 family	A0A0A1ELH3	Lactobacillus_phage	8.6e-39	46.8
WP_006731482.1\|477813_478125_+	hypothetical protein	A0A0A1EKX8	Lactobacillus_phage	2.3e-14	42.0
WP_006731448.1\|478185_478563_+	hypothetical protein	A0A0A1EKY4	Lactobacillus_phage	5.1e-16	45.1
WP_006731490.1\|478673_478988_+	hypothetical protein	NA	NA	NA	NA
WP_164823936.1\|479005_481861_+	tape measure protein	A0A1P8BLX4	Lactococcus_phage	3.1e-89	47.3
WP_164823937.1\|481864_482677_+\|tail	phage tail protein	A0A1P8BMI3	Lactococcus_phage	1.4e-21	32.1
WP_164823938.1\|482673_484431_+	hypothetical protein	A0A0A1ELH9	Lactobacillus_phage	2.1e-43	30.9

DBSCAN-SWA_3

601209 : 609513

Ectocarpus_siliculosus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164823973.1\|601209_602349_+	molecular chaperone DnaJ	Q8QNB4	Ectocarpus_siliculosus_virus	1.3e-22	25.5
WP_164823974.1\|602539_604378_+	elongation factor 4	A0A2K9L2P9	Tupanvirus	8.4e-19	37.1
WP_006730037.1\|604379_605066_+	class A sortase	NA	NA	NA	NA
WP_164785776.1\|605062_607348_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.3e-72	33.5
WP_006730035.1\|607443_607971_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	6.7e-22	39.0
WP_006732879.1\|608034_608991_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.0e-108	58.0
WP_006732882.1\|609012_609513_+	dihydrofolate reductase	G3MBI7	Bacillus_virus	1.4e-21	38.0

DBSCAN-SWA_4

671923 : 685559

unidentified_phage(12.5%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006730861.1\|671923_673117_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.0e-41	46.3
WP_006729975.1\|673214_673880_-	hemolysin III family protein	NA	NA	NA	NA
WP_164799154.1\|674006_674858_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	8.1e-17	41.1
WP_006731940.1\|674866_675094_+	YozE family protein	NA	NA	NA	NA
WP_164799155.1\|675098_676481_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	1.5e-12	28.8
WP_006731946.1\|676694_677534_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_006734115.1\|677530_678283_+	ribonuclease HII	E3T5H8	Cafeteria_roenbergensis_virus	2.0e-27	39.6
WP_006729969.1\|678331_679177_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	8.3e-30	34.1
WP_164823989.1\|679246_681334_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	3.7e-95	34.2
WP_164823990.1\|681383_682697_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_006730858.1\|682699_683623_+	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.0e-25	27.6
WP_164798704.1\|683626_684151_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
WP_164823991.1\|684161_685559_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IEP8	Erwinia_phage	1.4e-29	24.4

DBSCAN-SWA_5

927414 : 952765

Streptococcus_phage(85.71%)

transposase,integrase

attL 927357:927374|attR 931206:931223

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
927357:927374	attL	NA	NA	NA	NA
WP_006730188.1\|927414_928722_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	1.8e-92	47.6
WP_006730099.1\|929318_929792_+	universal stress protein	NA	NA	NA	NA
WP_001291561.1\|929976_931194_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|931275_931479_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
931206:931223	attR	NA	NA	NA	NA
WP_000857133.1\|931929_932160_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|932156_932579_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001240982.1\|933378_936297_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_000576156.1\|936300_936855_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_001038790.1\|937209_937947_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_001814874.1\|938071_938155_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_000336323.1\|938767_938935_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691736.1\|939053_940973_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
WP_001791010.1\|940988_941105_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|941349_942285_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_164824027.1\|942281_943283_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	8.4e-191	99.7
WP_000804748.1\|943279_945457_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_164824028.1\|945459_947907_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	99.9
WP_000506270.1\|947890_948397_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|948371_948869_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|948985_949207_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|949249_950455_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_000813488.1\|950634_952020_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|952048_952435_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|952450_952765_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

DBSCAN-SWA_6

1069280 : 1080256

Bacillus_virus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164824050.1\|1069280_1071509_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.9e-129	41.7
WP_102695497.1\|1071610_1072222_-	glycoside hydrolase family 73 protein	A0A0A7RUS8	Clostridium_phage	6.6e-21	41.1
WP_102695496.1\|1072224_1072836_-	ECF transporter S component	NA	NA	NA	NA
WP_102695495.1\|1073050_1074193_-	guanosine monophosphate reductase	A0A1V0SHK8	Klosneuvirus	7.2e-61	32.2
WP_164824051.1\|1074340_1077004_-	cation-translocating P-type ATPase	A0A1J0FA34	Only_Syngen_Nebraska_virus	4.1e-75	30.3
WP_006729618.1\|1077189_1078026_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	3.7e-67	52.9
WP_164824052.1\|1078028_1079507_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	5.0e-107	44.3
WP_006734163.1\|1079557_1080256_-	glycosyl transferase	A0A2K9L2U7	Tupanvirus	4.9e-12	28.1

DBSCAN-SWA_7

1114237 : 1127233

Streptococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006729584.1\|1114237_1114822_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.6e-51	51.8
WP_006730634.1\|1114930_1116187_-	AAA domain-containing protein	M1F3L1	Cronobacter_phage	5.9e-08	27.6
WP_164824066.1\|1116202_1117696_-	hypothetical protein	A0A191VYN2	Roseobacter_phage	3.9e-06	23.0
WP_006736366.1\|1117688_1118633_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	7.0e-46	37.1
WP_006733566.1\|1118632_1119667_-	YvcK family protein	A1IMD5	Streptococcus_phage	2.1e-91	52.7
WP_006729579.1\|1119679_1120555_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.0e-06	30.3
WP_164824067.1\|1120606_1123423_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.4e-296	54.8
WP_164824068.1\|1123450_1125448_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_006729576.1\|1125505_1127233_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.3e-138	45.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP049229

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP049228

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection