CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049937	Escherichia coli strain JL05 plasmid pARG01, complete sequence	0 crisprs	NA	0	0	1	0
NZ_CP049936	Escherichia coli strain JL05 chromosome, complete genome	10 crisprs	DinG,c2c9_V-U4,DEDDh,cas3,csa3,PD-DExK,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,RT	0	21	4	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

8135 : 22206

Escherichia_phage(42.86%)

integrase,transposase,protease

attL 8073:8132|attR 12608:13428

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8073:8132	attL	NA	NA	NA	NA
WP_001067858.1\|8135_8840_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001389366.1\|9395_9869_-	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
WP_000845048.1\|10026_11040_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_000454193.1\|11242_11593_+	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_071889079.1\|11718_12009_+	recombinase family protein	NA	NA	NA	NA
WP_001067858.1\|11899_12604_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_000027057.1\|13227_14088_+	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
12608:13428	attR	NA	NA	NA	NA
WP_001043260.1\|14332_15148_+	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
WP_001145207.1\|15252_16011_+	APH(3'') family aminoglycoside O-phosphotransferase	NA	NA	NA	NA
WP_000480968.1\|16010_16847_+	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
WP_000844627.1\|17233_17476_+\|transposase	transposase	NA	NA	NA	NA
WP_031606906.1\|17507_18134_-	tetracycline resistance transcriptional repressor TetR(A)	NA	NA	NA	NA
WP_025732387.1\|18239_19439_+	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
WP_001067858.1\|20047_20752_-\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	1.2e-138	99.6
WP_001398199.1\|20868_21270_-	type II toxin-antitoxin system toxin endoribonuclease PemK	NA	NA	NA	NA
WP_000557619.1\|21202_21460_-	type II toxin-antitoxin system antitoxin PemI	NA	NA	NA	NA
WP_000616807.1\|21552_22206_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP049936

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049936_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_1

341783-341905

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_1

>merge|NZ_CP049936|1|341783-341905|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>NZ_CP049936|1|1|341783-341905|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_001297805.1\|336632_337271_+\|YdhW-family-putative-oxidoreductase-system-protein	unknown	unknown	gnl\|CDD\|182160
NZ_CP049936.1\|WP_001273528.1\|334517_336620_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
NZ_CP049936.1\|WP_000102278.1\|350799_350889_+\|stress-response-protein-YnhF	unknown	unknown	unknown
NZ_CP049936.1\|WP_000007283.1\|352369_352951_-\|superoxide-dismutase-[Fe]	unknown	unknown	gnl\|CDD\|182534
NZ_CP049936.1\|WP_000098911.1\|345785_346934_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
NZ_CP049936.1\|WP_000493947.1\|345104_345746_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
NZ_CP049936.1\|WP_001295403.1\|331236_332649_-\|pyruvate-kinase-PykF	unknown	unknown	gnl\|CDD\|181699
NZ_CP049936.1\|WP_001174942.1\|343516_344890_-\|multidrug-efflux-MATE-transporter-MdtK	unknown	unknown	gnl\|CDD\|234981
NZ_CP049936.1\|WP_000212657.1\|341342_341648_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
NZ_CP049936.1\|WP_000716922.1\|339612_341217_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
NZ_CP049936.1\|WP_001069997.1\|337999_338785_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
NZ_CP049936.1\|WP_000534291.1\|342219_343476_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
NZ_CP049936.1\|WP_001310861.1\|337334_338003_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NZ_CP049936.1\|WP_000701040.1\|351054_352224_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NZ_CP049936.1\|WP_000190982.1\|349475_350501_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NZ_CP049936.1\|WP_000587560.1\|338788_339601_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
NZ_CP049936.1\|WP_001070230.1\|333870_334497_+\|ferredoxin-like-protein	unknown	unknown	gnl\|CDD\|182135
NZ_CP049936.1\|WP_001182362.1\|347222_348434_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
NZ_CP049936.1\|WP_000269501.1\|348546_349479_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
NZ_CP049936.1\|WP_000528342.1\|333205_333415_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_001297805.1\|336632_337271_+\|YdhW-family-putative-oxidoreductase-system-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.93584e-120
NZ_CP049936.1\|WP_001273528.1\|334517_336620_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
NZ_CP049936.1\|WP_000007283.1\|352369_352951_-\|superoxide-dismutase-[Fe]	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
NZ_CP049936.1\|WP_000098911.1\|345785_346934_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
NZ_CP049936.1\|WP_000493947.1\|345104_345746_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
NZ_CP049936.1\|WP_001295403.1\|331236_332649_-\|pyruvate-kinase-PykF	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
NZ_CP049936.1\|WP_001174942.1\|343516_344890_-\|multidrug-efflux-MATE-transporter-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
NZ_CP049936.1\|WP_000212657.1\|341342_341648_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	1.12003e-64
NZ_CP049936.1\|WP_000716922.1\|339612_341217_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
NZ_CP049936.1\|WP_001069997.1\|337999_338785_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	5.33298e-163
NZ_CP049936.1\|WP_000534291.1\|342219_343476_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
NZ_CP049936.1\|WP_001310861.1\|337334_338003_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	2.09652e-76
NZ_CP049936.1\|WP_000701040.1\|351054_352224_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
NZ_CP049936.1\|WP_000190982.1\|349475_350501_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NZ_CP049936.1\|WP_000587560.1\|338788_339601_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	8.20825e-175
NZ_CP049936.1\|WP_001070230.1\|333870_334497_+\|ferredoxin-like-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140
NZ_CP049936.1\|WP_001182362.1\|347222_348434_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
NZ_CP049936.1\|WP_000269501.1\|348546_349479_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
NZ_CP049936.1\|WP_000528342.1\|333205_333415_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34

>NZ_CP049936.1|WP_000212657.1|341342_341648_-|monooxygenase
MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA
>NZ_CP049936.1|WP_000716922.1|339612_341217_-|FAD-NAD(P)-binding-protein
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>NZ_CP049936.1|WP_000587560.1|338788_339601_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC
>NZ_CP049936.1|WP_001069997.1|337999_338785_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>NZ_CP049936.1|WP_001310861.1|337334_338003_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>NZ_CP049936.1|WP_001297805.1|336632_337271_+|YdhW-family-putative-oxidoreductase-system-protein
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>NZ_CP049936.1|WP_001273528.1|334517_336620_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>NZ_CP049936.1|WP_001070230.1|333870_334497_+|ferredoxin-like-protein
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>NZ_CP049936.1|WP_000528342.1|333205_333415_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>NZ_CP049936.1|WP_001295403.1|331236_332649_-|pyruvate-kinase-PykF
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>NZ_CP049936.1|WP_000534291.1|342219_343476_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>NZ_CP049936.1|WP_001174942.1|343516_344890_-|multidrug-efflux-MATE-transporter-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSVIILQRASR
>NZ_CP049936.1|WP_000493947.1|345104_345746_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>NZ_CP049936.1|WP_000098911.1|345785_346934_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>NZ_CP049936.1|WP_001182362.1|347222_348434_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVDCQNHGNAEVAHSESH
>NZ_CP049936.1|WP_000269501.1|348546_349479_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRVVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>NZ_CP049936.1|WP_000190982.1|349475_350501_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>NZ_CP049936.1|WP_000102278.1|350799_350889_+|stress-response-protein-YnhF
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>NZ_CP049936.1|WP_000701040.1|351054_352224_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>NZ_CP049936.1|WP_000007283.1|352369_352951_-|superoxide-dismutase-[Fe]
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP049936_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_2

379302-379433

Orphan

Consensus_repeat	Method
CTGTTGCTGTTCCAGCTTGCGCGCTTTGGCACGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_2

>merge|NZ_CP049936|2|379302-379433|CRISPRCasFinder
CTGTTGCTGTTCCAGCTTGCGCGCTTTGGCACGGGCAATAGCGGCTTCGACGGCGGCTTTGCGCGGATCGACCTGTTCTTCTGGTTCCGCATTAGCCTGTTGCTGTTCCAGCTTGCGCGCTTTGGCGCGGGC

>NZ_CP049936|2|2|379302-379433|CRISPRCasFinder
CTGTTGCTGTTCCAGCTTGCGCGCTTTGGCACGGGC	AATAGCGGCTTCGACGGCGGCTTTGCGCGGATCGACCTGTTCTTCTGGTTCCGCATTAGC
CTGTTGCTGTTCCAGCTTGCGCGCTTTGGCGCGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_000179513.1\|388860_389889_+\|mal-regulon-transcriptional-regulator-MalI	unknown	unknown	gnl\|CDD\|182193
NZ_CP049936.1\|WP_000217950.1\|382876_383092_-\|transcription-modulator-YdgT	unknown	unknown	gnl\|CDD\|182426
NZ_CP049936.1\|WP_000969095.1\|390995_391586_+\|DNA-binding-transcriptional-regulator-UidR	unknown	unknown	gnl\|CDD\|366102
NZ_CP049936.1\|WP_001282313.1\|370321_370978_+\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|235555
NZ_CP049936.1\|WP_001282516.1\|383732_384773_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|183212
NZ_CP049936.1\|WP_000920778.1\|377504_378125_-\|electron-transport-complex-subunit-RsxG	unknown	unknown	gnl\|CDD\|179350
NZ_CP049936.1\|WP_001300888.1\|383364_383490_-\|division-septum-protein-Blr	unknown	unknown	gnl\|CDD\|380226
NZ_CP049936.1\|WP_000991809.1\|381114_381693_-\|electron-transport-complex-subunit-RsxB	unknown	unknown	gnl\|CDD\|235347
NZ_CP049936.1\|WP_000459406.1\|385912_387085_-\|bifunctional-maltose-regulon-transcriptional-repressor/cystathionine-beta-lyase-MalY	unknown	unknown	gnl\|CDD\|224090
NZ_CP049936.1\|WP_000567490.1\|384807_385809_-\|adenosine-deaminase	unknown	unknown	gnl\|CDD\|236480
NZ_CP049936.1\|WP_000133193.1\|381692_382274_-\|electron-transport-complex-subunit-RsxA	unknown	unknown	gnl\|CDD\|235352
NZ_CP049936.1\|WP_000765762.1\|373346_373952_-\|glutathione-transferase-GstA	unknown	unknown	gnl\|CDD\|182533
NZ_CP049936.1\|WP_001030339.1\|376170_376806_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|182661
NZ_CP049936.1\|WP_000231922.1\|378128_379187_-\|electron-transport-complex-subunit-RsxD	unknown	unknown	gnl\|CDD\|234844
NZ_CP049936.1\|WP_000789751.1\|372442_373303_+\|pyridoxal-kinase-PdxY	unknown	unknown	gnl\|CDD\|235592
NZ_CP049936.1\|WP_000100931.1\|374057_375560_-\|dipeptide/tripeptide-permease-DtpA	unknown	unknown	gnl\|CDD\|181969
NZ_CP049936.1\|WP_001295400.1\|371106_372381_+\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NZ_CP049936.1\|WP_000061968.1\|369933_370263_+\|C-type-lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|236902
NZ_CP049936.1\|WP_001289654.1\|376805_377501_-\|electron-transport-complex-subunit-RsxE	unknown	unknown	gnl\|CDD\|237091
NZ_CP049936.1\|WP_000214176.1\|382350_382791_-\|DUF2569-domain-containing-protein	unknown	unknown	gnl\|CDD\|371223

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_000179513.1\|388860_389889_+\|mal-regulon-transcriptional-regulator-MalI	gnl\|CDD\|182193	PRK10014, PRK10014, DNA-binding transcriptional repressor MalI; Provisional.	0
NZ_CP049936.1\|WP_000217950.1\|382876_383092_-\|transcription-modulator-YdgT	gnl\|CDD\|182426	PRK10391, PRK10391, transcription modulator YdgT.	3.28395e-48
NZ_CP049936.1\|WP_000969095.1\|390995_391586_+\|DNA-binding-transcriptional-regulator-UidR	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.54876e-15
NZ_CP049936.1\|WP_001282313.1\|370321_370978_+\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|235555	PRK05679, PRK05679, pyridoxal 5'-phosphate synthase.	2.16351e-128
NZ_CP049936.1\|WP_001282516.1\|383732_384773_+\|oxidoreductase	gnl\|CDD\|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	0
NZ_CP049936.1\|WP_000920778.1\|377504_378125_-\|electron-transport-complex-subunit-RsxG	gnl\|CDD\|179350	PRK01908, PRK01908, electron transport complex protein RnfG; Validated.	1.58787e-142
NZ_CP049936.1\|WP_001300888.1\|383364_383490_-\|division-septum-protein-Blr	gnl\|CDD\|380226	NF033231, small_Blr, division septum protein Blr. Members of this family are Blr, named beta-lactam resistance protein because mutants have heightened sensitivity to beta-lactam antibiotics, but actually involved in cell division. The protein is very small.	5.592e-21
NZ_CP049936.1\|WP_000991809.1\|381114_381693_-\|electron-transport-complex-subunit-RsxB	gnl\|CDD\|235347	PRK05113, PRK05113, electron transport complex protein RnfB; Provisional.	1.4261e-131
NZ_CP049936.1\|WP_000459406.1\|385912_387085_-\|bifunctional-maltose-regulon-transcriptional-repressor/cystathionine-beta-lyase-MalY	gnl\|CDD\|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	0
NZ_CP049936.1\|WP_000567490.1\|384807_385809_-\|adenosine-deaminase	gnl\|CDD\|236480	PRK09358, PRK09358, adenosine deaminase; Provisional.	2.36853e-158
NZ_CP049936.1\|WP_000133193.1\|381692_382274_-\|electron-transport-complex-subunit-RsxA	gnl\|CDD\|235352	PRK05151, PRK05151, electron transport complex protein RsxA; Provisional.	3.94175e-115
NZ_CP049936.1\|WP_000765762.1\|373346_373952_-\|glutathione-transferase-GstA	gnl\|CDD\|182533	PRK10542, PRK10542, glutathionine S-transferase; Provisional.	5.09401e-154
NZ_CP049936.1\|WP_001030339.1\|376170_376806_-\|endonuclease-III	gnl\|CDD\|182661	PRK10702, PRK10702, endonuclease III; Provisional.	4.32467e-157
NZ_CP049936.1\|WP_000231922.1\|378128_379187_-\|electron-transport-complex-subunit-RsxD	gnl\|CDD\|234844	PRK00816, rnfD, electron transport complex protein RnfD; Reviewed.	0
NZ_CP049936.1\|WP_000789751.1\|372442_373303_+\|pyridoxal-kinase-PdxY	gnl\|CDD\|235592	PRK05756, PRK05756, pyridoxal kinase PdxY.	0
NZ_CP049936.1\|WP_000100931.1\|374057_375560_-\|dipeptide/tripeptide-permease-DtpA	gnl\|CDD\|181969	PRK09584, tppB, dipeptide/tripeptide permease DtpA.	0
NZ_CP049936.1\|WP_001295400.1\|371106_372381_+\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NZ_CP049936.1\|WP_000061968.1\|369933_370263_+\|C-type-lysozyme-inhibitor	gnl\|CDD\|236902	PRK11372, PRK11372, C-type lysozyme inhibitor.	3.50896e-79
NZ_CP049936.1\|WP_001289654.1\|376805_377501_-\|electron-transport-complex-subunit-RsxE	gnl\|CDD\|237091	PRK12405, PRK12405, electron transport complex RsxE subunit; Provisional.	7.48941e-133
NZ_CP049936.1\|WP_000214176.1\|382350_382791_-\|DUF2569-domain-containing-protein	gnl\|CDD\|371223	pfam10754, DUF2569, Protein of unknown function (DUF2569). This family is conserved in bacteria. The function is not known, but several members are annotated as being YdgK or a homolog thereof.	4.68364e-36

>NZ_CP049936.1|WP_000231922.1|378128_379187_-|electron-transport-complex-subunit-RsxD
MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQVIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGAGWQWVNLAWLAGGLWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPETLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
>NZ_CP049936.1|WP_000920778.1|377504_378125_-|electron-transport-complex-subunit-RsxG
MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQEALFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAVKKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE
>NZ_CP049936.1|WP_001289654.1|376805_377501_-|electron-transport-complex-subunit-RsxE
MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDGADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEATAERALPNGETGNV
>NZ_CP049936.1|WP_001030339.1|376170_376806_-|endonuclease-III
MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNGEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVEEKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI
>NZ_CP049936.1|WP_000100931.1|374057_375560_-|dipeptide/tripeptide-permease-DtpA
MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVNIGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINYRNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSPILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDPLMSLEVYGRVFLQIGVATAIIAVLMLLTAPKLHRMTQDDAADKAAKAAVA
>NZ_CP049936.1|WP_000765762.1|373346_373952_-|glutathione-transferase-GstA
MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYFVVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK
>NZ_CP049936.1|WP_000789751.1|372442_373303_+|pyridoxal-kinase-PdxY
MKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAKPEHYFSATKL
>NZ_CP049936.1|WP_001295400.1|371106_372381_+|tyrosine--tRNA-ligase
MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
>NZ_CP049936.1|WP_001282313.1|370321_370978_+|pyridoxamine-5'-phosphate-oxidase
MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
>NZ_CP049936.1|WP_000061968.1|369933_370263_+|C-type-lysozyme-inhibitor
MSMKKLLLICLPVLLTGCSAFNQLVEHMQTATLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNCQLQNPQR
>NZ_CP049936.1|WP_000991809.1|381114_381693_-|electron-transport-complex-subunit-RsxB
MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
>NZ_CP049936.1|WP_000133193.1|381692_382274_-|electron-transport-complex-subunit-RsxA
MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
>NZ_CP049936.1|WP_000214176.1|382350_382791_-|DUF2569-domain-containing-protein
MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTFQTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAVKAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP
>NZ_CP049936.1|WP_000217950.1|382876_383092_-|transcription-modulator-YdgT
MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
>NZ_CP049936.1|WP_001300888.1|383364_383490_-|division-septum-protein-Blr
MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK
>NZ_CP049936.1|WP_001282516.1|383732_384773_+|oxidoreductase
MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVKADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVRDRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSYPQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRDGVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGIESAKHRATLCLA
>NZ_CP049936.1|WP_000567490.1|384807_385809_-|adenosine-deaminase
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK
>NZ_CP049936.1|WP_000459406.1|385912_387085_-|bifunctional-maltose-regulon-transcriptional-repressor/cystathionine-beta-lyase-MalY
MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAPCIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDTQTVVYGPSVIYMVSELIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADDWFCDMGKLEAVLAKPECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWSNVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTAHIAAYQQGAPWLDALRVYLKDNLTYISDKMNAAFPELNWQIPQSTYLAWLDLRPLNIDDNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR
>NZ_CP049936.1|WP_000179513.1|388860_389889_+|mal-regulon-transcriptional-regulator-MalI
MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAAIEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHGGKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVDTVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSDWVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDRYFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGTTLADRMMQKITHEETHSRNLIIPARLIAAK
>NZ_CP049936.1|WP_000969095.1|390995_391586_+|DNA-binding-transcriptional-regulator-UidR
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLLDLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP049936_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_3

956203-956294

Orphan

Consensus_repeat	Method
CCACCTTTTTTACCTGCTTCAGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_3

>merge|NZ_CP049936|3|956203-956294|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGCGCGCTGCGGGTCATTCTTGAAATTCCCCCCGCTGTGCTGTCCACCTTTTTTACCTGCTTCTGATGC

>NZ_CP049936|3|3|956203-956294|CRISPRCasFinder
CCACCTTTTTTACCTGCTTCAGATGC	GCGCTGCGGGTCATTCTTGAAATTCCCCCCGCTGTGCTGT
CCACCTTTTTTACCTGCTTCTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_001307708.1\|951736_952429_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	unknown	unknown	gnl\|CDD\|163356
NZ_CP049936.1\|WP_001240629.1\|954760_956089_+\|pyrimidine-utilization-transport-protein-G	unknown	unknown	gnl\|CDD\|132655
NZ_CP049936.1\|WP_000191700.1\|949719_950358_-\|HTH-type-transcriptional-regulator-RutR	unknown	unknown	gnl\|CDD\|184970
NZ_CP049936.1\|WP_000209854.1\|961966_962566_-\|molecular-chaperone-TorD	unknown	unknown	gnl\|CDD\|235326
NZ_CP049936.1\|WP_001307099.1\|952834_953635_+\|pyrimidine-utilization-protein-D	unknown	unknown	gnl\|CDD\|211851
NZ_CP049936.1\|WP_001062102.1\|962562_965109_-\|trimethylamine-N-oxide-reductase-TorA	unknown	unknown	gnl\|CDD\|237909
NZ_CP049936.1\|WP_001028095.1\|954245_954740_+\|pyrimidine-utilization-flavin-reductase-protein-F	unknown	unknown	gnl\|CDD\|132654
NZ_CP049936.1\|WP_001151437.1\|956717_957314_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NZ_CP049936.1\|WP_001120112.1\|966410_967103_+\|two-component-system-response-regulator-TorR	unknown	unknown	gnl\|CDD\|182711
NZ_CP049936.1\|WP_001001196.1\|953644_954235_+\|malonic-semialdehyde-reductase	unknown	unknown	gnl\|CDD\|180040
NZ_CP049936.1\|WP_001299828.1\|945717_949680_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP049936.1\|WP_001297176.1\|950645_951737_+\|pyrimidine-utilization-protein-A	unknown	unknown	gnl\|CDD\|163355
NZ_CP049936.1\|WP_001230242.1\|965108_966281_-\|pentaheme-c-type-cytochrome-TorC	unknown	unknown	gnl\|CDD\|184992
NZ_CP049936.1\|WP_000535359.1\|959129_960389_-\|YccE-family-protein	unknown	unknown	gnl\|CDD\|182074
NZ_CP049936.1\|WP_001044263.1\|957599_958841_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	unknown	unknown	gnl\|CDD\|182284
NZ_CP049936.1\|WP_001143120.1\|957334_957562_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182285
NZ_CP049936.1\|WP_000420629.1\|960648_961569_+\|curved-DNA-binding-protein	unknown	unknown	gnl\|CDD\|182347
NZ_CP049936.1\|WP_000979516.1\|945453_945663_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049936.1\|WP_000024561.1\|961568_961874_+\|chaperone-modulator-CbpM	unknown	unknown	gnl\|CDD\|182346
NZ_CP049936.1\|WP_001126780.1\|952440_952827_+\|pyrimidine-utilization-protein-C	unknown	unknown	gnl\|CDD\|274677

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_001307708.1\|951736_952429_+\|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	5.84226e-169
NZ_CP049936.1\|WP_001240629.1\|954760_956089_+\|pyrimidine-utilization-transport-protein-G	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	0
NZ_CP049936.1\|WP_000191700.1\|949719_950358_-\|HTH-type-transcriptional-regulator-RutR	gnl\|CDD\|184970	PRK15008, PRK15008, HTH-type transcriptional regulator RutR; Provisional.	1.12845e-153
NZ_CP049936.1\|WP_000209854.1\|961966_962566_-\|molecular-chaperone-TorD	gnl\|CDD\|235326	PRK04976, torD, chaperone protein TorD; Validated.	1.10573e-83
NZ_CP049936.1\|WP_001307099.1\|952834_953635_+\|pyrimidine-utilization-protein-D	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	1.96403e-140
NZ_CP049936.1\|WP_001062102.1\|962562_965109_-\|trimethylamine-N-oxide-reductase-TorA	gnl\|CDD\|237909	PRK15102, PRK15102, trimethylamine-N-oxide reductase TorA.	0
NZ_CP049936.1\|WP_001028095.1\|954245_954740_+\|pyrimidine-utilization-flavin-reductase-protein-F	gnl\|CDD\|132654	TIGR03615, flavoprotein_oxidoreductase, pyrimidine utilization flavin reductase protein F. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the flavin reductase family defined by pfam01613. Presumably, this protein recycles the flavin of the RutA luciferase-like oxidoreductase.	3.76111e-106
NZ_CP049936.1\|WP_001151437.1\|956717_957314_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	8.51484e-133
NZ_CP049936.1\|WP_001001196.1\|953644_954235_+\|malonic-semialdehyde-reductase	gnl\|CDD\|180040	PRK05365, PRK05365, malonic semialdehyde reductase; Provisional.	1.45614e-128
NZ_CP049936.1\|WP_001299828.1\|945717_949680_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP049936.1\|WP_001297176.1\|950645_951737_+\|pyrimidine-utilization-protein-A	gnl\|CDD\|163355	TIGR03612, RutA, pyrimidine utilization protein A. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the luciferase family defined by pfam00296 and is likely a FMN-dependent monoxygenase. [Unknown function, Enzymes of unknown specificity].	0
NZ_CP049936.1\|WP_001230242.1\|965108_966281_-\|pentaheme-c-type-cytochrome-TorC	gnl\|CDD\|184992	PRK15032, PRK15032, pentaheme c-type cytochrome TorC.	0
NZ_CP049936.1\|WP_000535359.1\|959129_960389_-\|YccE-family-protein	gnl\|CDD\|182074	PRK09784, PRK09784, YccE family protein.	0
NZ_CP049936.1\|WP_001044263.1\|957599_958841_-\|bifunctional-glucose-1-phosphatase/inositol-phosphatase	gnl\|CDD\|182284	PRK10173, PRK10173, glucose-1-phosphatase/inositol phosphatase; Provisional.	0
NZ_CP049936.1\|WP_001120112.1\|966410_967103_+\|two-component-system-response-regulator-TorR	gnl\|CDD\|182711	PRK10766, PRK10766, two-component system response regulator TorR.	5.89892e-138
NZ_CP049936.1\|WP_000420629.1\|960648_961569_+\|curved-DNA-binding-protein	gnl\|CDD\|182347	PRK10266, PRK10266, curved DNA-binding protein.	0
NZ_CP049936.1\|WP_001143120.1\|957334_957562_+\|hypothetical-protein	gnl\|CDD\|182285	PRK10174, PRK10174, hypothetical protein; Provisional.	8.66725e-44
NZ_CP049936.1\|WP_000024561.1\|961568_961874_+\|chaperone-modulator-CbpM	gnl\|CDD\|182346	PRK10265, PRK10265, chaperone modulator CbpM.	2.74017e-64
NZ_CP049936.1\|WP_001126780.1\|952440_952827_+\|pyrimidine-utilization-protein-C	gnl\|CDD\|274677	TIGR03610, RutC, pyrimidine utilization protein C. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the endoribonuclease L-PSP family defined by pfam01042.	5.99808e-85

>NZ_CP049936.1|WP_001240629.1|954760_956089_+|pyrimidine-utilization-transport-protein-G
MAMFGFPHWQLKSTSTESGVVAPYERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAPIAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAMLLGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP
>NZ_CP049936.1|WP_001028095.1|954245_954740_+|pyrimidine-utilization-flavin-reductase-protein-F
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
>NZ_CP049936.1|WP_001001196.1|953644_954235_+|malonic-semialdehyde-reductase
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTVEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFAGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
>NZ_CP049936.1|WP_001307099.1|952834_953635_+|pyrimidine-utilization-protein-D
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
>NZ_CP049936.1|WP_001126780.1|952440_952827_+|pyrimidine-utilization-protein-C
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>NZ_CP049936.1|WP_001307708.1|951736_952429_+|peroxyureidoacrylate/ureidoacrylate-amidohydrolase-RutB
MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>NZ_CP049936.1|WP_001297176.1|950645_951737_+|pyrimidine-utilization-protein-A
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA
>NZ_CP049936.1|WP_000191700.1|949719_950358_-|HTH-type-transcriptional-regulator-RutR
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEIFFNQTVENVQRIIIEGIRPR
>NZ_CP049936.1|WP_001299828.1|945717_949680_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>NZ_CP049936.1|WP_000979516.1|945453_945663_-|hypothetical-protein
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>NZ_CP049936.1|WP_001151437.1|956717_957314_+|NAD(P)H:quinone-oxidoreductase
MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>NZ_CP049936.1|WP_001143120.1|957334_957562_+|hypothetical-protein
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>NZ_CP049936.1|WP_001044263.1|957599_958841_-|bifunctional-glucose-1-phosphatase/inositol-phosphatase
MNKTLIAAAVAGIVLIASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAFSEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNERTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDANGFCPMDKFDSVLNEAVK
>NZ_CP049936.1|WP_000535359.1|959129_960389_-|YccE-family-protein
MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSGGITYTIQYVQNVDIVRVSLPGRGSESITDFKGYYWYGFMEYIENITACDDVFSEYCLDDENMSIQPEWINTPGISDLDTGIDLSGISFIQSEINKTYGLKYAPVDGDGYCLLRAILVLKEHEYSWALGSHKTQKQVYEEFIKIVDKQTIEALVDTAFNDLREDVKTLFGVNLQSDNKIQGQGGFLSWSFLSFKKEFIDSCLNDKKCILHLPEFIFNDNKVRLVLDTDPEQRVNEVKNFLTALSDSICSLFIVNSNMASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAIY
>NZ_CP049936.1|WP_000420629.1|960648_961569_+|curved-DNA-binding-protein
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGHDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>NZ_CP049936.1|WP_000024561.1|961568_961874_+|chaperone-modulator-CbpM
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVTHP
>NZ_CP049936.1|WP_000209854.1|961966_962566_-|molecular-chaperone-TorD
MTTLTAQQIACIYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNALENRIAALTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCHQHDSFGFYAALSQLLLVLVECDHQNR
>NZ_CP049936.1|WP_001062102.1|962562_965109_-|trimethylamine-N-oxide-reductase-TorA
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS
>NZ_CP049936.1|WP_001230242.1|965108_966281_-|pentaheme-c-type-cytochrome-TorC
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHGAPEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>NZ_CP049936.1|WP_001120112.1|966410_967103_+|two-component-system-response-regulator-TorR
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTRAEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC

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Crispr_ID: NZ_CP049936_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_4

2040342-2040474

Orphan

Consensus_repeat	Method
ATCACCAATATTGAAAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP049936_4

>merge|NZ_CP049936|4|2040342-2040474|PILER-CR
ATCACCAATATTGAAAATGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTCCTCACCAATATTGAAAACATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGGATCACCAATATTGAAAG

>NZ_CP049936|4|1|2040342-2040474|PILER-CR
ATCACCAATATTGAAAA	TGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGTTC
CTCACCAATATTGAAAA	CATGGCGTAGCAAAAAGAAATTTTCAATATTGCTTTATGG
ATCACCAATATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_001297614.1\|2044831_2046385_+\|crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
NZ_CP049936.1\|WP_000600725.1\|2034877_2035408_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	unknown	unknown	gnl\|CDD\|234852
NZ_CP049936.1\|WP_000543608.1\|2053458_2054280_-\|4-hydroxy-tetrahydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|223366
NZ_CP049936.1\|WP_000692200.1\|2039480_2040251_-\|electron-transfer-flavoprotein-FixA	unknown	unknown	gnl\|CDD\|179569
NZ_CP049936.1\|WP_000610901.1\|2031047_2031425_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP049936.1\|WP_001126376.1\|2048615_2051837_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393
NZ_CP049936.1\|WP_000004397.1\|2046493_2047279_+\|crotonobetainyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|179599
NZ_CP049936.1\|WP_000257186.1\|2031431_2032274_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	unknown	unknown	gnl\|CDD\|273208
NZ_CP049936.1\|WP_000624375.1\|2032351_2032831_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
NZ_CP049936.1\|WP_000122876.1\|2047284_2047875_+\|carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
NZ_CP049936.1\|WP_000787111.1\|2040724_2042239_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	unknown	unknown	gnl\|CDD\|179568
NZ_CP049936.1\|WP_000377194.1\|2033022_2034885_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
NZ_CP049936.1\|WP_000597260.1\|2051854_2053003_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP049936.1\|WP_000347117.1\|2042269_2043412_+\|crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
NZ_CP049936.1\|WP_000333120.1\|2047960_2048356_-\|carnitine-metabolism-transcriptional-regulator-CaiF	unknown	unknown	gnl\|CDD\|183154
NZ_CP049936.1\|WP_000203741.1\|2036904_2037192_-\|ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
NZ_CP049936.1\|WP_000349932.1\|2043540_2044758_+\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589
NZ_CP049936.1\|WP_001091499.1\|2038524_2039466_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|235120
NZ_CP049936.1\|WP_001065381.1\|2030223_2031045_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP049936.1\|WP_001183198.1\|2035515_2036847_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_001297614.1\|2044831_2046385_+\|crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0
NZ_CP049936.1\|WP_000600725.1\|2034877_2035408_-\|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	2.99389e-133
NZ_CP049936.1\|WP_000543608.1\|2053458_2054280_-\|4-hydroxy-tetrahydrodipicolinate-reductase	gnl\|CDD\|223366	COG0289, DapB, Dihydrodipicolinate reductase [Amino acid transport and metabolism].	3.40114e-141
NZ_CP049936.1\|WP_000692200.1\|2039480_2040251_-\|electron-transfer-flavoprotein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	8.73835e-169
NZ_CP049936.1\|WP_000610901.1\|2031047_2031425_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	3.63315e-76
NZ_CP049936.1\|WP_001126376.1\|2048615_2051837_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NZ_CP049936.1\|WP_000004397.1\|2046493_2047279_+\|crotonobetainyl-CoA-hydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	4.82171e-178
NZ_CP049936.1\|WP_000257186.1\|2031431_2032274_+\|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)	gnl\|CDD\|273208	TIGR00668, Bis5'-nucleosyl-tetraphosphatase_symmetrical, bis(5'-nucleosyl)-tetraphosphatase (symmetrical). Diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) is a regulatory metabolite of stress conditions. It is hydrolyzed to two ADP by this enzyme. Alternate names include diadenosine-tetraphosphatase and Ap4A hydrolase. [Cellular processes, Adaptations to atypical conditions].	0
NZ_CP049936.1\|WP_000624375.1\|2032351_2032831_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.07206e-127
NZ_CP049936.1\|WP_000122876.1\|2047284_2047875_+\|carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	2.12106e-142
NZ_CP049936.1\|WP_000787111.1\|2040724_2042239_+\|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
NZ_CP049936.1\|WP_000377194.1\|2033022_2034885_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP049936.1\|WP_000597260.1\|2051854_2053003_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP049936.1\|WP_000347117.1\|2042269_2043412_+\|crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
NZ_CP049936.1\|WP_000333120.1\|2047960_2048356_-\|carnitine-metabolism-transcriptional-regulator-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	2.96175e-74
NZ_CP049936.1\|WP_000203741.1\|2036904_2037192_-\|ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	1.84173e-69
NZ_CP049936.1\|WP_000349932.1\|2043540_2044758_+\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0
NZ_CP049936.1\|WP_001091499.1\|2038524_2039466_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0
NZ_CP049936.1\|WP_001065381.1\|2030223_2031045_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	2.76119e-148
NZ_CP049936.1\|WP_001183198.1\|2035515_2036847_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.4298e-59

>NZ_CP049936.1|WP_000692200.1|2039480_2040251_-|electron-transfer-flavoprotein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLAADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>NZ_CP049936.1|WP_001091499.1|2038524_2039466_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>NZ_CP049936.1|WP_000203741.1|2036904_2037192_-|ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>NZ_CP049936.1|WP_001183198.1|2035515_2036847_-|MFS-transporter
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>NZ_CP049936.1|WP_000600725.1|2034877_2035408_-|glutathione-regulated-potassium-efflux-system-oxidoreductase-KefF
MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>NZ_CP049936.1|WP_000377194.1|2033022_2034885_-|glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>NZ_CP049936.1|WP_000624375.1|2032351_2032831_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>NZ_CP049936.1|WP_000257186.1|2031431_2032274_+|bis(5'-nucleosyl)-tetraphosphatase-(symmetrical)
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEAAAS
>NZ_CP049936.1|WP_000610901.1|2031047_2031425_+|Co2+/Mg2+-efflux-protein-ApaG
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
>NZ_CP049936.1|WP_001065381.1|2030223_2031045_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
>NZ_CP049936.1|WP_000787111.1|2040724_2042239_+|L-carnitine/gamma-butyrobetaine-antiport-BCCT-transporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
>NZ_CP049936.1|WP_000347117.1|2042269_2043412_+|crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>NZ_CP049936.1|WP_000349932.1|2043540_2044758_+|L-carnitine-CoA-transferase
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>NZ_CP049936.1|WP_001297614.1|2044831_2046385_+|crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>NZ_CP049936.1|WP_000004397.1|2046493_2047279_+|crotonobetainyl-CoA-hydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIFRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>NZ_CP049936.1|WP_000122876.1|2047284_2047875_+|carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>NZ_CP049936.1|WP_000333120.1|2047960_2048356_-|carnitine-metabolism-transcriptional-regulator-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>NZ_CP049936.1|WP_001126376.1|2048615_2051837_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>NZ_CP049936.1|WP_000597260.1|2051854_2053003_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK
>NZ_CP049936.1|WP_000543608.1|2053458_2054280_-|4-hydroxy-tetrahydrodipicolinate-reductase
MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSSKESGLFDMRDVLDLNSL

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Crispr_ID: NZ_CP049936_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_5

2274563-2274712

Orphan

Consensus_repeat	Method
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_5

>merge|NZ_CP049936|5|2274563-2274712|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCATGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

>NZ_CP049936|5|4|2274563-2274712|CRISPRCasFinder
TGAACGCCTTATCCGACCTACACAGCACTGAACTCGTAGGCCTGATAAGACGCG	CAAGCGTCGCATCAGGCAATGCTGTTATTGTCGGATGCGGCA
TGAACGCCTTATCCGACCTACACAGCACCGAACTCGTAGGCCTGATAAGACGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_096934322.1\|2279620_2280124_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP049936.1\|WP_000416392.1\|2275322_2278178_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_CP049936.1\|WP_000012908.1\|2280747_2281761_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179587
NZ_CP049936.1\|WP_095866757.1\|2262797_2263817_+\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186
NZ_CP049936.1\|WP_000786393.1\|2274879_2275323_+\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NZ_CP049936.1\|WP_000002953.1\|2280169_2280586_-\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NZ_CP049936.1\|WP_001356017.1\|2268944_2270447_+\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP049936.1\|WP_000583470.1\|2283627_2284080_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
NZ_CP049936.1\|WP_000397144.1\|2273014_2274526_+\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NZ_CP049936.1\|WP_001128347.1\|2266482_2267802_+\|gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
NZ_CP049936.1\|WP_000998695.1\|2265655_2266420_+\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
NZ_CP049936.1\|WP_000079660.1\|2278231_2279428_-\|DUF898-domain-containing-protein	unknown	unknown	gnl\|CDD\|226719
NZ_CP049936.1\|WP_000584114.1\|2271647_2272748_-\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NZ_CP049936.1\|WP_001197411.1\|2264600_2265632_+\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
NZ_CP049936.1\|WP_001295681.1\|2270565_2271648_-\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NZ_CP049936.1\|WP_001309159.1\|2267868_2268867_+\|DNA-binding-transcriptional-regulator-IdnR	unknown	unknown	gnl\|CDD\|380489
NZ_CP049936.1\|WP_001324323.1\|2281921_2283505_-\|DNA-binding-protein	unknown	unknown	unknown
NZ_CP049936.1\|WP_000896738.1\|2263820_2264384_-\|gluconokinase	unknown	unknown	gnl\|CDD\|182097
NZ_CP049936.1\|WP_000500725.1\|2284888_2285602_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|183714
NZ_CP049936.1\|WP_000256670.1\|2284224_2284818_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_096934322.1\|2279620_2280124_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.36746e-18
NZ_CP049936.1\|WP_000416392.1\|2275322_2278178_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_CP049936.1\|WP_000012908.1\|2280747_2281761_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179587	PRK03515, PRK03515, ornithine carbamoyltransferase subunit I; Provisional.	0
NZ_CP049936.1\|WP_095866757.1\|2262797_2263817_+\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.77635e-169
NZ_CP049936.1\|WP_000786393.1\|2274879_2275323_+\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	3.51045e-66
NZ_CP049936.1\|WP_000002953.1\|2280169_2280586_-\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	4.50628e-69
NZ_CP049936.1\|WP_001356017.1\|2268944_2270447_+\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP049936.1\|WP_000583470.1\|2283627_2284080_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	3.50239e-70
NZ_CP049936.1\|WP_000397144.1\|2273014_2274526_+\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NZ_CP049936.1\|WP_001128347.1\|2266482_2267802_+\|gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP049936.1\|WP_000998695.1\|2265655_2266420_+\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
NZ_CP049936.1\|WP_000079660.1\|2278231_2279428_-\|DUF898-domain-containing-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	1.11898e-150
NZ_CP049936.1\|WP_000584114.1\|2271647_2272748_-\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NZ_CP049936.1\|WP_001197411.1\|2264600_2265632_+\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
NZ_CP049936.1\|WP_001295681.1\|2270565_2271648_-\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NZ_CP049936.1\|WP_001309159.1\|2267868_2268867_+\|DNA-binding-transcriptional-regulator-IdnR	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	1.4437e-109
NZ_CP049936.1\|WP_000896738.1\|2263820_2264384_-\|gluconokinase	gnl\|CDD\|182097	PRK09825, idnK, gluconokinase.	1.3617e-126
NZ_CP049936.1\|WP_000500725.1\|2284888_2285602_+\|SDR-family-oxidoreductase	gnl\|CDD\|183714	PRK12742, PRK12742, SDR family oxidoreductase.	2.9267e-149
NZ_CP049936.1\|WP_000256670.1\|2284224_2284818_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.0374e-10

>NZ_CP049936.1|WP_000397144.1|2273014_2274526_+|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NZ_CP049936.1|WP_000584114.1|2271647_2272748_-|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NZ_CP049936.1|WP_001295681.1|2270565_2271648_-|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NZ_CP049936.1|WP_001356017.1|2268944_2270447_+|DUF853-domain-containing-protein
MSEPLLIARTPDTKLFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGVAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDTNGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDVKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDEVDRESAYEMLQKGVQASAEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NZ_CP049936.1|WP_001309159.1|2267868_2268867_+|DNA-binding-transcriptional-regulator-IdnR
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL
>NZ_CP049936.1|WP_001128347.1|2266482_2267802_+|gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIVFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>NZ_CP049936.1|WP_000998695.1|2265655_2266420_+|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>NZ_CP049936.1|WP_001197411.1|2264600_2265632_+|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>NZ_CP049936.1|WP_000896738.1|2263820_2264384_-|gluconokinase
MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNIDKMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHFLWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTEQCRQAVLAIRQNRICAKEGSASDQRCE
>NZ_CP049936.1|WP_095866757.1|2262797_2263817_+|NADPH-dependent-aldehyde-reductase-Ahr
MSMVKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADY
>NZ_CP049936.1|WP_000786393.1|2274879_2275323_+|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTIDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NZ_CP049936.1|WP_000416392.1|2275322_2278178_+|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVVLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NZ_CP049936.1|WP_000079660.1|2278231_2279428_-|DUF898-domain-containing-protein
MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFFYFAILMTVSADMPLVGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKGFWWVTFFLPILMAIGMGTVFFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIMPSLPFL
>NZ_CP049936.1|WP_096934322.1|2279620_2280124_+|GNAT-family-N-acetyltransferase
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKHCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLREL
>NZ_CP049936.1|WP_000002953.1|2280169_2280586_-|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>NZ_CP049936.1|WP_000012908.1|2280747_2281761_+|ornithine-carbamoyltransferase
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSKLNN
>NZ_CP049936.1|WP_001324323.1|2281921_2283505_-|DNA-binding-protein
MSKISGWNFSQNITSADNCKQKNEDLDTWYVGMNDFARIAGGQNSRSNILSPRAFLEFLAKIFTLGYVDFSKRSNEAGRNMMAHIKSSSYIKNNDGSEIMKFVMNNPEGERADLSKVEIEITLASAFNNGIREGHTVIIFTQPDGSTNRYEGKSFERKDESSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLEKPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGILKEIDDLNAVNNYLLNNKKATDNEINDIKVNLSHILIDSLDDAKVNLTPVIDSILEIFLKFPYINDVRILDWCFNKRMQYFGDSEKIKYACSVINHIDFSRDQSKDFSCDQSKIKIAETLFFNLDKEHYKNSRKLQELIWDKLVAYVNDFNLSNQEKSRLILRLFDDVKLLFNEVPVSILVNDIFLKDFFMKQPDFAKWYFYQLIKKYEGEQLYLNELGYVYGNEEKTNEIVKKHPGYVIKIFEEKMGNELKIRTRMMKILRNGKINIYEYINI
>NZ_CP049936.1|WP_000583470.1|2283627_2284080_-|YhcH/YjgK/YiaL-family-protein
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>NZ_CP049936.1|WP_000256670.1|2284224_2284818_-|TetR/AcrR-family-transcriptional-regulator
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLEGIHSHDPLARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAALAGEAIKTLLKE
>NZ_CP049936.1|WP_000500725.1|2284888_2285602_+|SDR-family-oxidoreductase
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAKRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA

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Crispr_ID: NZ_CP049936_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_6

3495051-3495302

Orphan

Consensus_repeat	Method
TTTTGGAGGAGCAGAAAGATGAATGACTGTCCACGACACTATACCCAAAAGAAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP049936_6

>merge|NZ_CP049936|6|3495051-3495302|PILER-CR
AGATGAATGACTGTCCACGACAGAACCCGGCTTATCGGTCAGTTTCACCTGATTTACGTAAAAACCCGCTTCGGCGGGTTTTTGCTTTTGGAGGAGCGGAAAGATGAATGACTGTCCACGACGCTATACCCAAAAGAAAGCGGCTTATCGGTCAGTTTCACCTGGTTTACGTAAAAAACCGCTTCGGCGGGTTTTTGCTTTTGGAGGGGCAGAAAGATGAATGACTGTCCACGACACTATACCCAAAAGAAA

>NZ_CP049936|6|2|3495051-3495302|PILER-CR
AGATGAATGACTGTCCACGACAGAACCCGGCTTATCGGTCAGTTTCACCTGATTT	ACGTAAAAACCCGCTTCGGCGGGTTTTTGCTTTTGGAGGAGCGGAAAGATGAATGACTGTCCA
CGACGCTATACCCAAAAGAAAGCGGCTTATCGGTCAGTTTCACCTGGTTTACGTA	AAAAACCGCTTCGGCGGGTTTTTGCTTTTGGAGGGGCAGAAAGATGAATGACTGTCCAC
GACACTATACCCAAAAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_000104211.1\|3498136_3499075_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP049936.1\|WP_000145820.1\|3497604_3497949_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP049936.1\|WP_001307405.1\|3487978_3488314_-\|type-II-toxin-antitoxin-system-antitoxin-PrlF	unknown	unknown	gnl\|CDD\|236638
NZ_CP049936.1\|WP_000072187.1\|3486650_3487460_+\|aga-operon-transcriptional-regulator-AgaR	unknown	unknown	gnl\|CDD\|182086
NZ_CP049936.1\|WP_000107720.1\|3500184_3501516_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP049936.1\|WP_001273741.1\|3488462_3490034_-\|galactarate-dehydratase	unknown	unknown	gnl\|CDD\|274491
NZ_CP049936.1\|WP_001058227.1\|3491758_3492529_+\|2-dehydro-3-deoxyglucarate-aldolase	unknown	unknown	gnl\|CDD\|182547
NZ_CP049936.1\|WP_001297162.1\|3501541_3502750_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP049936.1\|WP_001303675.1\|3492558_3493449_+\|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl\|CDD\|183197
NZ_CP049936.1\|WP_000347266.1\|3487514_3487979_-\|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV	unknown	unknown	gnl\|CDD\|371659
NZ_CP049936.1\|WP_001299416.1\|3493545_3494691_+\|glycerate-2-kinase	unknown	unknown	gnl\|CDD\|182392
NZ_CP049936.1\|WP_000675743.1\|3496809_3497349_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049936.1\|WP_001295547.1\|3484625_3485099_-\|PTS-N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|183129
NZ_CP049936.1\|WP_000599636.1\|3490408_3491743_+\|galactarate/glucarate/glycerate-transporter-GarP	unknown	unknown	gnl\|CDD\|273326
NZ_CP049936.1\|WP_000719990.1\|3505091_3505481_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP049936.1\|WP_000075593.1\|3495600_3496788_-\|YhaC-family-protein	unknown	unknown	gnl\|CDD\|182043
NZ_CP049936.1\|WP_000548347.1\|3499173_3500163_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP049936.1\|WP_000681921.1\|3485121_3486402_-\|tagatose-bisphosphate-aldolase-subunit-KbaZ	unknown	unknown	gnl\|CDD\|185355
NZ_CP049936.1\|WP_000622115.1\|3505552_3506917_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP049936.1\|WP_000861734.1\|3502783_3505078_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_000104211.1\|3498136_3499075_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP049936.1\|WP_000145820.1\|3497604_3497949_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NZ_CP049936.1\|WP_001307405.1\|3487978_3488314_-\|type-II-toxin-antitoxin-system-antitoxin-PrlF	gnl\|CDD\|236638	PRK09974, PRK09974, type II toxin-antitoxin system PrlF family antitoxin.	5.08893e-52
NZ_CP049936.1\|WP_000072187.1\|3486650_3487460_+\|aga-operon-transcriptional-regulator-AgaR	gnl\|CDD\|182086	PRK09802, PRK09802, DeoR family transcriptional regulator.	0
NZ_CP049936.1\|WP_001297162.1\|3501541_3502750_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP049936.1\|WP_001273741.1\|3488462_3490034_-\|galactarate-dehydratase	gnl\|CDD\|274491	TIGR03248, galactar-dH20, galactarate dehydratase. Galactarate dehydratase converts D-galactarate to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0714).	0
NZ_CP049936.1\|WP_001058227.1\|3491758_3492529_+\|2-dehydro-3-deoxyglucarate-aldolase	gnl\|CDD\|182547	PRK10558, PRK10558, alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional.	0
NZ_CP049936.1\|WP_000861734.1\|3502783_3505078_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP049936.1\|WP_001303675.1\|3492558_3493449_+\|2-hydroxy-3-oxopropionate-reductase	gnl\|CDD\|183197	PRK11559, garR, tartronate semialdehyde reductase; Provisional.	0
NZ_CP049936.1\|WP_000347266.1\|3487514_3487979_-\|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV	gnl\|CDD\|371659	pfam11663, Toxin_YhaV, Toxin with endonuclease activity, of toxin-antitoxin system. YhaV causes reversible bacteriostasis and is part of a toxin-antitoxin system in Escherichia coli along with PrlF. The toxicity of YhaV is counteracted by PrlF by the formation of a tight complex which binds to the promoter of the prlF-yhaV operon. In vitro, YhaV also has endonuclease activity.	8.32738e-72
NZ_CP049936.1\|WP_001299416.1\|3493545_3494691_+\|glycerate-2-kinase	gnl\|CDD\|182392	PRK10342, PRK10342, glycerate kinase I; Provisional.	0
NZ_CP049936.1\|WP_000107720.1\|3500184_3501516_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP049936.1\|WP_001295547.1\|3484625_3485099_-\|PTS-N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|183129	PRK11425, PRK11425, PTS N-acetylgalactosamine transporter subunit IIB.	2.31755e-109
NZ_CP049936.1\|WP_000599636.1\|3490408_3491743_+\|galactarate/glucarate/glycerate-transporter-GarP	gnl\|CDD\|273326	TIGR00893, Probable_glucarate_transporter, D-galactonate transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.8374e-134
NZ_CP049936.1\|WP_000719990.1\|3505091_3505481_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP049936.1\|WP_000075593.1\|3495600_3496788_-\|YhaC-family-protein	gnl\|CDD\|182043	PRK09716, PRK09716, YhaC family protein.	0
NZ_CP049936.1\|WP_000548347.1\|3499173_3500163_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP049936.1\|WP_000681921.1\|3485121_3486402_-\|tagatose-bisphosphate-aldolase-subunit-KbaZ	gnl\|CDD\|185355	PRK15458, PRK15458, tagatose 6-phosphate aldolase subunit KbaZ; Provisional.	0
NZ_CP049936.1\|WP_000622115.1\|3505552_3506917_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0

>NZ_CP049936.1|WP_001299416.1|3493545_3494691_+|glycerate-2-kinase
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSIPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNEIGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG
>NZ_CP049936.1|WP_001303675.1|3492558_3493449_+|2-hydroxy-3-oxopropionate-reductase
MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
>NZ_CP049936.1|WP_001058227.1|3491758_3492529_+|2-dehydro-3-deoxyglucarate-aldolase
MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
>NZ_CP049936.1|WP_000599636.1|3490408_3491743_+|galactarate/glucarate/glycerate-transporter-GarP
MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK
>NZ_CP049936.1|WP_001273741.1|3488462_3490034_-|galactarate-dehydratase
MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTLPLATKVPAPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDLLPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLVGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
>NZ_CP049936.1|WP_001307405.1|3487978_3488314_-|type-II-toxin-antitoxin-system-antitoxin-PrlF
MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE
>NZ_CP049936.1|WP_000347266.1|3487514_3487979_-|type-II-toxin-antitoxin-system-ribonuclease-toxin-YhaV
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRFFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH
>NZ_CP049936.1|WP_000072187.1|3486650_3487460_+|aga-operon-transcriptional-regulator-AgaR
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLRRQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE
>NZ_CP049936.1|WP_000681921.1|3485121_3486402_-|tagatose-bisphosphate-aldolase-subunit-KbaZ
MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYYTACEGQ
>NZ_CP049936.1|WP_001295547.1|3484625_3485099_-|PTS-N-acetylgalactosamine-transporter-subunit-IIB
MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQQNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRINVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL
>NZ_CP049936.1|WP_000075593.1|3495600_3496788_-|YhaC-family-protein
MSPVSSIGNDISSDLVRRKMNDLPESPIGNNLEALAPGIEKLKQTSIQMVTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRLDFLGYNAQIIQRSDNTCELTINEPLKNQEISTGNINVNCPLKDIYNEIRRLNVIFSCGTGDIVDLSSLDLRNVDLDYYDFTDKHMANTILNPFKLDSTNFTNANMFQVNFVSSTQNVTISWGYLLKITPVLISISDMYSEEKIKFVESCLNELGDITEEQLKIMRFAIIKSIPRATLTDKLENELTKEIYKSSSKINNYLNRIKLPEMKGFSSEKIDYYIDIIIKDYESVKENAYLIDPKINYNTDLNIEDSSSEEFLSDNTLEKDENSPDNCFEVVKYNTYEAYNSENQYFTREDYTYNYDLLNAI
>NZ_CP049936.1|WP_000675743.1|3496809_3497349_-|hypothetical-protein
MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTNDVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRIQPENMSPFIIDISTGEHDDYIIQTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTQKEAILTPPTHFNKTCITSDYWQILFFSPDHFNNDFY
>NZ_CP049936.1|WP_000145820.1|3497604_3497949_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP049936.1|WP_000104211.1|3498136_3499075_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP049936.1|WP_000548347.1|3499173_3500163_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP049936.1|WP_000107720.1|3500184_3501516_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP049936.1|WP_001297162.1|3501541_3502750_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP049936.1|WP_000861734.1|3502783_3505078_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP049936.1|WP_000719990.1|3505091_3505481_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP049936.1|WP_000622115.1|3505552_3506917_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG

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Crispr_ID: NZ_CP049936_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_7

3509882-3509999

Orphan

Consensus_repeat	Method
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_7

>merge|NZ_CP049936|7|3509882-3509999|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGGGTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGATGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

>NZ_CP049936|7|5|3509882-3509999|CRISPRCasFinder
TGCCGGATGCGATGCTGGCGCACCTTATCCGGCCTACGGG	GTGCTCAACTTGTTGATGTTGTTGTGTTTTGTACCTGA
TGCCGGATGCGATGCTGGCGCATCTTATCCGGCCTACGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_000104211.1\|3498136_3499075_+\|transcriptional-regulator-TdcA	unknown	unknown	gnl\|CDD\|182391
NZ_CP049936.1\|WP_000384145.1\|3512610_3512976_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP049936.1\|WP_000145820.1\|3497604_3497949_-\|DNA-binding-transcriptional-activator-TdcR	unknown	unknown	gnl\|CDD\|236909
NZ_CP049936.1\|WP_000861734.1\|3502783_3505078_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	unknown	unknown	gnl\|CDD\|153087
NZ_CP049936.1\|WP_001297162.1\|3501541_3502750_+\|propionate-kinase	unknown	unknown	gnl\|CDD\|183484
NZ_CP049936.1\|WP_001198780.1\|3512012_3512369_-\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|225694
NZ_CP049936.1\|WP_000401598.1\|3507191_3508523_+\|HAAAP-family-serine/threonine-permease	unknown	unknown	gnl\|CDD\|273283
NZ_CP049936.1\|WP_000107720.1\|3500184_3501516_+\|threonine/serine-transporter-TdcC	unknown	unknown	gnl\|CDD\|184191
NZ_CP049936.1\|WP_000633577.1\|3510259_3510961_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NZ_CP049936.1\|WP_000031415.1\|3515598_3515904_-\|DUF883-domain-containing-protein	unknown	unknown	gnl\|CDD\|226941
NZ_CP049936.1\|WP_000785722.1\|3515191_3515596_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227681
NZ_CP049936.1\|WP_001041010.1\|3511065_3511962_+\|DNA-binding-transcriptional-regulator-YhaJ	unknown	unknown	gnl\|CDD\|176122
NZ_CP049936.1\|WP_000622115.1\|3505552_3506917_+\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|185000
NZ_CP049936.1\|WP_000719990.1\|3505091_3505481_+\|enamine/imine-deaminase	unknown	unknown	gnl\|CDD\|105214
NZ_CP049936.1\|WP_000531193.1\|3513268_3514255_-\|glutathionyl-hydroquinone-reductase-YqjG	unknown	unknown	gnl\|CDD\|223512
NZ_CP049936.1\|WP_000548347.1\|3499173_3500163_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	unknown	unknown	gnl\|CDD\|236317
NZ_CP049936.1\|WP_000096086.1\|3514902_3515202_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372871
NZ_CP049936.1\|WP_001297155.1\|3514324_3514807_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_CP049936.1\|WP_001295544.1\|3510072_3510237_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049936.1\|WP_000460519.1\|3508550_3509861_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_000104211.1\|3498136_3499075_+\|transcriptional-regulator-TdcA	gnl\|CDD\|182391	PRK10341, PRK10341, transcriptional regulator TdcA.	0
NZ_CP049936.1\|WP_000384145.1\|3512610_3512976_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	3.68376e-42
NZ_CP049936.1\|WP_000145820.1\|3497604_3497949_-\|DNA-binding-transcriptional-activator-TdcR	gnl\|CDD\|236909	PRK11424, PRK11424, DNA-binding transcriptional activator TdcR; Provisional.	3.36123e-66
NZ_CP049936.1\|WP_000861734.1\|3502783_3505078_+\|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase	gnl\|CDD\|153087	cd01678, PFL1, Pyruvate formate lyase 1. Pyruvate formate lyase catalyzes a key step in anaerobic glycolysis, the conversion of pyruvate and CoenzymeA to formate and acetylCoA. The PFL mechanism involves an unusual radical cleavage of pyruvate in which two cysteines and one glycine form radicals that are required for catalysis. PFL has a ten-stranded alpha/beta barrel domain that is structurally similar to those of all three ribonucleotide reductase (RNR) classes as well as benzylsuccinate synthase and B12-independent glycerol dehydratase.	0
NZ_CP049936.1\|WP_001297162.1\|3501541_3502750_+\|propionate-kinase	gnl\|CDD\|183484	PRK12379, PRK12379, propionate kinase.	0
NZ_CP049936.1\|WP_000401598.1\|3507191_3508523_+\|HAAAP-family-serine/threonine-permease	gnl\|CDD\|273283	TIGR00814, membrane_transport_protein_YhjV, serine transporter. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- serine/threonine subfamily (TC 2.A.42.2) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for hydroxy amino acid transporters and includes the serine permease, SdaC, of E. coli, and the threonine permease, TdcC, of E. coli.//added GO terms, none avaialbelf or ser/thr specifically [SS 2/6/05] [Transport and binding proteins, Amino acids, peptides and amines].	2.53913e-167
NZ_CP049936.1\|WP_000107720.1\|3500184_3501516_+\|threonine/serine-transporter-TdcC	gnl\|CDD\|184191	PRK13629, PRK13629, threonine/serine transporter TdcC; Provisional.	0
NZ_CP049936.1\|WP_001297155.1\|3514324_3514807_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.8408e-29
NZ_CP049936.1\|WP_000031415.1\|3515598_3515904_-\|DUF883-domain-containing-protein	gnl\|CDD\|226941	COG4575, ElaB, Uncharacterized conserved protein [Function unknown].	1.46625e-41
NZ_CP049936.1\|WP_000785722.1\|3515191_3515596_-\|hypothetical-protein	gnl\|CDD\|227681	COG5393, COG5393, Predicted membrane protein [Function unknown].	2.73939e-60
NZ_CP049936.1\|WP_001041010.1\|3511065_3511962_+\|DNA-binding-transcriptional-regulator-YhaJ	gnl\|CDD\|176122	cd08431, PBP2_HupR, The C-terminal substrate binding domain of LysR-type transcriptional regulator, HupR, which regulates expression of the heme uptake receptor HupA; contains the type 2 periplasmic binding fold. HupR, a member of the LysR family, activates hupA transcription under low-iron conditions in the presence of hemin. The expression of many iron-uptake genes, such as hupA, is regulated at the transcriptional level by iron and an iron-binding repressor protein called Fur (ferric uptake regulation). Under iron-abundant conditions with heme, the active Fur repressor protein represses transcription of the iron-uptake gene hupA, and prevents transcriptional activation via HupR. Under low-iron conditions with heme, the Fur repressor is inactive and transcription of the hupA is allowed. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.2986e-51
NZ_CP049936.1\|WP_001198780.1\|3512012_3512369_-\|DUF805-domain-containing-protein	gnl\|CDD\|225694	COG3152, COG3152, Predicted membrane protein [Function unknown].	1.64644e-35
NZ_CP049936.1\|WP_000633577.1\|3510259_3510961_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.02982e-67
NZ_CP049936.1\|WP_000531193.1\|3513268_3514255_-\|glutathionyl-hydroquinone-reductase-YqjG	gnl\|CDD\|223512	COG0435, ECM4, Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP049936.1\|WP_000548347.1\|3499173_3500163_+\|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB	gnl\|CDD\|236317	PRK08638, PRK08638, bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB.	0
NZ_CP049936.1\|WP_000096086.1\|3514902_3515202_-\|hypothetical-protein	gnl\|CDD\|372871	pfam13997, YqjK, YqjK-like protein. The YqjK-like protein family includes the E. coli YqjK protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 100 amino acids in length. There is a single completely conserved residue R that may be functionally important.	6.11451e-20
NZ_CP049936.1\|WP_000719990.1\|3505091_3505481_+\|enamine/imine-deaminase	gnl\|CDD\|105214	PRK11401, PRK11401, enamine/imine deaminase.	2.43767e-83
NZ_CP049936.1\|WP_000622115.1\|3505552_3506917_+\|L-serine-ammonia-lyase	gnl\|CDD\|185000	PRK15040, PRK15040, L-serine ammonia-lyase.	0
NZ_CP049936.1\|WP_000460519.1\|3508550_3509861_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	0

>NZ_CP049936.1|WP_000460519.1|3508550_3509861_+|serine-dehydratase-subunit-alpha-family-protein
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>NZ_CP049936.1|WP_000401598.1|3507191_3508523_+|HAAAP-family-serine/threonine-permease
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>NZ_CP049936.1|WP_000622115.1|3505552_3506917_+|L-serine-ammonia-lyase
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLSHDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>NZ_CP049936.1|WP_000719990.1|3505091_3505481_+|enamine/imine-deaminase
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>NZ_CP049936.1|WP_000861734.1|3502783_3505078_+|2-ketobutyrate-formate-lyase/pyruvate-formate-lyase
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPDMLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>NZ_CP049936.1|WP_001297162.1|3501541_3502750_+|propionate-kinase
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
>NZ_CP049936.1|WP_000107720.1|3500184_3501516_+|threonine/serine-transporter-TdcC
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>NZ_CP049936.1|WP_000548347.1|3499173_3500163_+|bifunctional-threonine-ammonia-lyase/L-serine-ammonia-lyase-TdcB
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA
>NZ_CP049936.1|WP_000104211.1|3498136_3499075_+|transcriptional-regulator-TdcA
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKLQDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>NZ_CP049936.1|WP_000145820.1|3497604_3497949_-|DNA-binding-transcriptional-activator-TdcR
MTGITIFYGDNIIRYVVNIKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINTAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>NZ_CP049936.1|WP_001295544.1|3510072_3510237_-|hypothetical-protein
MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>NZ_CP049936.1|WP_000633577.1|3510259_3510961_-|pirin-family-protein
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVWLHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>NZ_CP049936.1|WP_001041010.1|3511065_3511962_+|DNA-binding-transcriptional-regulator-YhaJ
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSSEINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFSGK
>NZ_CP049936.1|WP_001198780.1|3512012_3512369_-|DUF805-domain-containing-protein
MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEGNSGSNRYGNDPKFGSN
>NZ_CP049936.1|WP_000384145.1|3512610_3512976_-|DUF805-domain-containing-protein
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>NZ_CP049936.1|WP_000531193.1|3513268_3514255_-|glutathionyl-hydroquinone-reductase-YqjG
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYISLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
>NZ_CP049936.1|WP_001297155.1|3514324_3514807_-|DoxX-family-protein
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>NZ_CP049936.1|WP_000096086.1|3514902_3515202_-|hypothetical-protein
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
>NZ_CP049936.1|WP_000785722.1|3515191_3515596_-|hypothetical-protein
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>NZ_CP049936.1|WP_000031415.1|3515598_3515904_-|DUF883-domain-containing-protein
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR

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Crispr_ID: NZ_CP049936_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_8

3901239-3902914

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

27 spacers

cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NZ_CP049936_8

>merge|NZ_CP049936|8|3901239-3902914|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGGCATTGACGCTTTAAACGACGACGGACGCCACGTGTTCCCCGCGCCAGCGGGGATAAACCGAAAACAGCCTTTAGATTAGTACCTGACGACCGGTGTTCCCCGCGCCAGCGGGGATAAACCGTAAACGCACCTGGCGCGCCACTTTATCAACAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCTTGTTTAATTGCGTGGAACGTCTCAATTGTGTTCCCCGCGCCAGCGGGGATAAACCGACGGCGTGGATTGAGGGACGGGTATTTGGTCCGTGTTCCCCGCGCCAGCGGGGATAAACCTAGATCGCGCCACGAGGAAACGAATATGAACGGGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCCGCCAGGCCAGCGACACATCAGACAACTGGTGTTCCCCGCGCCAGCGGGGATAAACCGGTCTGTGATGGCCTGCTCGTGAGTCCGCGGCGGTGTTCCCCGCGCCAGCGGGGATAAACCGTTTTGATTTCATTAACGGCGCTCCCCATATTTGTGTTCCCCGCGCCAGCGGGGATAAACCGTGCGCCGTAGCGTGTCCACCTATTGTAGTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGATACAAACGCGGTGTTTATCAATATGAATTTTGTGTTCCCCGCGCCAGCGGGGATAAACCGGCACCACGCGTACCCCGATGTTTGTTTTGCCAGTGTTCCCCGCGCCAGCGGGGATAAACCGATCCGGCTATATCTTTGAGCATTACAGAAATAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTATTGCTTTCGTACAGATTTTCAGTGGTGCTGTGTTCCCCGCGCCAGCGGGGATAAACCGAAAATTCTGTGTTTCGACCATTACTTCGGTAAGTGTTCCCCGCGCCAGCGGGGATAAACCGATTCTTGATCACGCTTTTACCGAAGTAATGGTGTGTTCCCCGCGCCAGCGGGGATAAACCGGGGGTAGAATTATTCTTCGTGAGCGATTTATCGTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCGTTCCGTGCGGCAATTGGAATCACACCAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGTTCTGAATCCGATATTCTTCAGCACCTTCAGTGTTCCCCGCGCCAGCGGGGATAAACCGAGCGTCAATCAGCGCGTCTATCGCGTCACTTTGTGTTCCCCGCGCCAGCGGGGATAAACCGATTTGGGGGTATGAGAGCGCCGAGCCGTTCGGGTGTTCCCCGCGCCAGCGGGGATAAACCGGCTCCCTGTCAGTTGTAATCGATAACGTTGATGTGTTCCCCGCGCCAGCGGGGATAAACCGATGTAGGGGCAATCGAACGATTCTCTGCCGACGTGTTCCCCGCGCCAGCGGGGATAAACCGCCGAGCCCGATTATCGGCATGAGCGATGCGGAGTGTTCCCCGCGCCAGCGGGGATAAACCGTCGAAGAAGAAAGGGAAATAATGCGAGGAACGGTGTTCCCCGCGCCAGCGGGGATAAACCGTATTACGCGCCAGCAATGCTGACAGCGGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCGCGAGAGCCAGCAAAACGCCAGGGCACAAAAGAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP049936|8|3|3901239-3902853|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATTGACGCTTTAAACGACGACGGACGCCAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAACAGCCTTTAGATTAGTACCTGACGACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACGCACCTGGCGCGCCACTTTATCAACAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGTGGATTGAGGGACGGGTATTTGGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCT	AGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACAAACGCGGTGTTTATCAATATGAATTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCACCACGCGTACCCCGATGTTTGTTTTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGGCTATATCTTTGAGCATTACAGAAATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGCTTTCGTACAGATTTTCAGTGGTGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAATTCTGTGTTTCGACCATTACTTCGGTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGTAGAATTATTCTTCGTGAGCGATTTATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCGTTCCGTGCGGCAATTGGAATCACACCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTTCTGAATCCGATATTCTTCAGCACCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCGTCAATCAGCGCGTCTATCGCGTCACTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTGGGGGTATGAGAGCGCCGAGCCGTTCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP049936|8|6|3901239-3902914|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATTGACGCTTTAAACGACGACGGACGCCAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAACAGCCTTTAGATTAGTACCTGACGACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACGCACCTGGCGCGCCACTTTATCAACAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGTGGATTGAGGGACGGGTATTTGGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCT	AGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACAAACGCGGTGTTTATCAATATGAATTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCACCACGCGTACCCCGATGTTTGTTTTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGGCTATATCTTTGAGCATTACAGAAATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGCTTTCGTACAGATTTTCAGTGGTGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAATTCTGTGTTTCGACCATTACTTCGGTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGTAGAATTATTCTTCGTGAGCGATTTATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCGTTCCGTGCGGCAATTGGAATCACACCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTTCTGAATCCGATATTCTTCAGCACCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCGTCAATCAGCGCGTCTATCGCGTCACTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTGGGGGTATGAGAGCGCCGAGCCGTTCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGAGAGCCAGCAAAACGCCAGGGCACAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCA

>NZ_CP049936|8|1|3901239-3902914|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCATTGACGCTTTAAACGACGACGGACGCCAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAACAGCCTTTAGATTAGTACCTGACGACCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TAAACGCACCTGGCGCGCCACTTTATCAACAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCTTGTTTAATTGCGTGGAACGTCTCAATT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACGGCGTGGATTGAGGGACGGGTATTTGGTCC
GTGTTCCCCGCGCCAGCGGGGATAAACCT	AGATCGCGCCACGAGGAAACGAATATGAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCCGCCAGGCCAGCGACACATCAGACAACTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GTCTGTGATGGCCTGCTCGTGAGTCCGCGGCG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTGATTTCATTAACGGCGCTCCCCATATTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TGCGCCGTAGCGTGTCCACCTATTGTAGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATACAAACGCGGTGTTTATCAATATGAATTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCACCACGCGTACCCCGATGTTTGTTTTGCCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGGCTATATCTTTGAGCATTACAGAAATA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTATTGCTTTCGTACAGATTTTCAGTGGTGCT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AAAATTCTGTGTTTCGACCATTACTTCGGTAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTCTTGATCACGCTTTTACCGAAGTAATGGT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGGTAGAATTATTCTTCGTGAGCGATTTATC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGGCGTTCCGTGCGGCAATTGGAATCACACCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGTTCTGAATCCGATATTCTTCAGCACCTTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	AGCGTCAATCAGCGCGTCTATCGCGTCACTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTGGGGGTATGAGAGCGCCGAGCCGTTCGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCTCCCTGTCAGTTGTAATCGATAACGTTGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ATGTAGGGGCAATCGAACGATTCTCTGCCGAC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCGAGCCCGATTATCGGCATGAGCGATGCGGA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TCGAAGAAGAAAGGGAAATAATGCGAGGAACG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TATTACGCGCCAGCAATGCTGACAGCGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGCGAGAGCCAGCAAAACGCCAGGGCACAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_000226815.1\|3891071_3893306_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
NZ_CP049936.1\|WP_000793004.1\|3898533_3899439_-\|YgcG-family-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP049936.1\|WP_001084076.1\|3912553_3914116_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP049936.1\|WP_000034929.1\|3898135_3898498_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049936.1\|WP_000036723.1\|3896781_3898080_+\|phosphopyruvate-hydratase	unknown	unknown	gnl\|CDD\|234617
NZ_CP049936.1\|WP_000956458.1\|3909410_3909563_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP049936.1\|WP_000254745.1\|3893631_3893967_+\|endoribonuclease-MazF	unknown	unknown	gnl\|CDD\|182138
NZ_CP049936.1\|WP_000039843.1\|3908411_3909146_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP049936.1\|WP_001071648.1\|3894037_3894829_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569
NZ_CP049936.1\|WP_165746357.1\|3909756_3912456_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP049936.1\|WP_001317283.1\|3903551_3904106_-\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|212662
NZ_CP049936.1\|WP_000211936.1\|3904826_3906626_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|182862
NZ_CP049936.1\|WP_001199982.1\|3900227_3900899_+\|7-carboxy-7-deazaguanine-synthase-QueE	unknown	unknown	gnl\|CDD\|275126
NZ_CP049936.1\|WP_000987944.1\|3904145_3904511_-\|6-carboxytetrahydropterin-synthase-QueD	unknown	unknown	gnl\|CDD\|238264
NZ_CP049936.1\|WP_000210878.1\|3895056_3896694_+\|CTP-synthase-(glutamine-hydrolyzing)	unknown	unknown	gnl\|CDD\|235437
NZ_CP049936.1\|WP_001379137.1\|3899452_3900055_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP049936.1\|WP_000029315.1\|3914112_3914649_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP049936.1\|WP_001290706.1\|3906625_3908338_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	unknown	unknown	gnl\|CDD\|237402
NZ_CP049936.1\|WP_000206429.1\|3914663_3915719_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP049936.1\|WP_000581937.1\|3893383_3893632_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_000226815.1\|3891071_3893306_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
NZ_CP049936.1\|WP_000793004.1\|3898533_3899439_-\|YgcG-family-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.06471e-80
NZ_CP049936.1\|WP_001084076.1\|3912553_3914116_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP049936.1\|WP_000036723.1\|3896781_3898080_+\|phosphopyruvate-hydratase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
NZ_CP049936.1\|WP_000956458.1\|3909410_3909563_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP049936.1\|WP_000254745.1\|3893631_3893967_+\|endoribonuclease-MazF	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	2.42227e-74
NZ_CP049936.1\|WP_000039843.1\|3908411_3909146_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP049936.1\|WP_001071648.1\|3894037_3894829_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
NZ_CP049936.1\|WP_165746357.1\|3909756_3912456_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76236e-177
NZ_CP049936.1\|WP_001317283.1\|3903551_3904106_-\|carbohydrate-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	5.41884e-35
NZ_CP049936.1\|WP_000211936.1\|3904826_3906626_+\|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit	gnl\|CDD\|182862	PRK10953, cysJ, NADPH-dependent assimilatory sulfite reductase flavoprotein subunit.	0
NZ_CP049936.1\|WP_001199982.1\|3900227_3900899_+\|7-carboxy-7-deazaguanine-synthase-QueE	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	9.11521e-156
NZ_CP049936.1\|WP_000987944.1\|3904145_3904511_-\|6-carboxytetrahydropterin-synthase-QueD	gnl\|CDD\|238264	cd00470, PTPS, 6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is PTPS which catalyzes the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin. The functional enzyme is a hexamer of identical subunits.	9.8593e-60
NZ_CP049936.1\|WP_000210878.1\|3895056_3896694_+\|CTP-synthase-(glutamine-hydrolyzing)	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP049936.1\|WP_001379137.1\|3899452_3900055_-\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.00218e-77
NZ_CP049936.1\|WP_000029315.1\|3914112_3914649_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.47989e-27
NZ_CP049936.1\|WP_001290706.1\|3906625_3908338_+\|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
NZ_CP049936.1\|WP_000206429.1\|3914663_3915719_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	8.2231e-155
NZ_CP049936.1\|WP_000581937.1\|3893383_3893632_+\|type-II-toxin-antitoxin-system-antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48

>NZ_CP049936.1|WP_001199982.1|3900227_3900899_+|7-carboxy-7-deazaguanine-synthase-QueE
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGSASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>NZ_CP049936.1|WP_001379137.1|3899452_3900055_-|LemA-family-protein
MLRTFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRADLIPNLVASIKGYSNHEKDVLEAVTLARSQANRASSDLQQTPGNEQKLQAWQQAQAQVTRTLGQLTIISERYPELKAQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKFPAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNASAH
>NZ_CP049936.1|WP_000793004.1|3898533_3899439_-|YgcG-family-protein
MKNLILLLVLICSSAFAVQVPVPEFAKYINDLTGTLTREEVSTLTSQIKTLTQKSHAQLIVLVVETTGDETIEQYATRVFERWQPGHKNLDDGILLVVAWQDHTVHIEIGYGLEGILTDAQSGQIIRNSIIPAFKKGDLAVGLQQGIGDIETRLSENDLVNNTSPDHPLPFSGWWALLVWAIVLTFISARGYVKTLGVICFAAIILAFVLPIAGYSGSWGVLATLLCFATPFLVVAIAFTPFGRKVRDSMRSANRPSRYERSNSASRHSSSSSSSSSSSFNNDNFSGGGGSSGGGGASGRW
>NZ_CP049936.1|WP_000034929.1|3898135_3898498_-|hypothetical-protein
MSKILANHPRLSKFVFGLFGAAGMIWLNKAFQGDELFQLITSLLALDTFVYFCIYSLINPIPEANDFLWDYKVHQRKYSSNISHNDFVSNVRNSRKIVRILILVGITFINVIALLTKLKM
>NZ_CP049936.1|WP_000036723.1|3896781_3898080_+|phosphopyruvate-hydratase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>NZ_CP049936.1|WP_000210878.1|3895056_3896694_+|CTP-synthase-(glutamine-hydrolyzing)
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>NZ_CP049936.1|WP_001071648.1|3894037_3894829_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>NZ_CP049936.1|WP_000254745.1|3893631_3893967_+|endoribonuclease-MazF
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>NZ_CP049936.1|WP_000581937.1|3893383_3893632_+|type-II-toxin-antitoxin-system-antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>NZ_CP049936.1|WP_000226815.1|3891071_3893306_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>NZ_CP049936.1|WP_001317283.1|3903551_3904106_-|carbohydrate-kinase
MLGCCVLDIWGMTWKTTATLLLLVPVLQAPLARYAWIYRSILESVALMLKNNYDNMRNEMNHFAKHVIITGGGSNSDLFMQIFADMFNLPARRNAINGCASLGAAINKAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHNDVILKKSYEVMHGELGNVDSIQSWSNA
>NZ_CP049936.1|WP_000987944.1|3904145_3904511_-|6-carboxytetrahydropterin-synthase-QueD
MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>NZ_CP049936.1|WP_000211936.1|3904826_3906626_+|NADPH-dependent-assimilatory-sulfite-reductase-flavoprotein-subunit
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLTGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGELRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>NZ_CP049936.1|WP_001290706.1|3906625_3908338_+|assimilatory-sulfite-reductase-(NADPH)-hemoprotein-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>NZ_CP049936.1|WP_000039843.1|3908411_3909146_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP049936.1|WP_000956458.1|3909410_3909563_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP049936.1|WP_165746357.1|3909756_3912456_+|CRISPR-associated-helicase-Cas3'
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDNDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPTSSLSLFHSRFAFSDRQRIETKTLARFGKEGSSQRAGKALISTQVLEQSVDCDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPDEEWFGSAMRNSAYIYPDHGRIWLTQRVLRQQGAIQMPHSARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYTTGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILVTDNESCGYSATEGLIGKVG
>NZ_CP049936.1|WP_001084076.1|3912553_3914116_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGIRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQDDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHRFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADGLLSKWNKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP049936.1|WP_000029315.1|3914112_3914649_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKDGHKATLRKWHEELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVAANVKAIDERQPFAAQLAAVMSEGRFTCLSAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP049936.1|WP_000206429.1|3914663_3915719_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLSLLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA

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Crispr_ID: NZ_CP049936_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_9

3918415-3919178

TypeI-E

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGGG	PILER-CR

12 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_CP049936_9

>merge|NZ_CP049936|9|3918415-3919178|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCGCGACAAAATTCTCAAAACTCGATCAGGAAAATGTGTTCCCCGCGCCAGCGGGGATAAACCGCCACCGTTTTCGCCCACCAGGGCGCACAACCCGTGTTCCCCGCGCCAGCGGGGATAAACCGGAAAAAGAGAAGGTAGAGAAAGCGGAATCTGGGTGTTCCCCGCGCCAGCGGGGATAAACCGCAGGTCTATCGGGCGATCAATAAAATCGGTCAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCGCACCGTTGCGTCGAAAAGGCGCTGGAGATGTGTTCCCCGCGCCAGCGGGGATAAACCGTACGCTTACACAACGGGCGAATATTTTAACGGGTGTTCCCCGCGCCAGCGGGGATAAACCGGAACCCAATAGTGAAATACAGCATCATTTTTTGTGTTCCCCGCGCCAGCGGGGATAAACCGACCTGGAGGCGAAAAAGGCGCTTCGACGTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGGCCTATATCTCTAACCGCATCGGGCTGCGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGGGCAAATATAAATTCCAGCGTGCTTCATGAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGGGCAAATATAAATTCCAGCGTGCTTCATGAAGTGTTCCCCGCGCCAGCGGGGATAAACCGCTGCGTAGCGACCTTTGCTCTCAATTTCGTTGGTGTTCCCCGCGCCAGCGGGGATAAACCGGG

>NZ_CP049936|9|7|3918415-3919176|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGACAAAATTCTCAAAACTCGATCAGGAAAAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCACCGTTTTCGCCCACCAGGGCGCACAACCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAAAGAGAAGGTAGAGAAAGCGGAATCTGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGTCTATCGGGCGATCAATAAAATCGGTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACCGTTGCGTCGAAAAGGCGCTGGAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGCTTACACAACGGGCGAATATTTTAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACCCAATAGTGAAATACAGCATCATTTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACCTGGAGGCGAAAAAGGCGCTTCGACGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGGCCTATATCTCTAACCGCATCGGGCTGCGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCGTAGCGACCTTTGCTCTCAATTTCGTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP049936|9|2|3918415-3919176|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CGACAAAATTCTCAAAACTCGATCAGGAAAAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCACCGTTTTCGCCCACCAGGGCGCACAACCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAAAGAGAAGGTAGAGAAAGCGGAATCTGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGTCTATCGGGCGATCAATAAAATCGGTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACCGTTGCGTCGAAAAGGCGCTGGAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGCTTACACAACGGGCGAATATTTTAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACCCAATAGTGAAATACAGCATCATTTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	ACCTGGAGGCGAAAAAGGCGCTTCGACGTAAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAGGCCTATATCTCTAACCGCATCGGGCTGCGC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GGGCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CTGCGTAGCGACCTTTGCTCTCAATTTCGTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCG

>NZ_CP049936|9|4|3918476-3918870|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CCACCGTTTTCGCCCACCAGGGCGCACAACCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAAAGAGAAGGTAGAGAAAGCGGAATCTGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGTCTATCGGGCGATCAATAAAATCGGTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACCGTTGCGTCGAAAAGGCGCTGGAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGCTTACACAACGGGCGAATATTTTAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACCCAATAGTGAAATACAGCATCATTTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCGACCTGGAGGCGAAAAAGGCGCTTCGACGTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGGCCTATATCTCTAACCGCATCGGGCTGCGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGG	GCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCGGG	GCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCGCT	GCGTAGCGACCTTTGCTCTCAATTTCGTTG


>NZ_CP049936|9|5|3918965-3919178|PILER-CR
	CCACCGTTTTCGCCCACCAGGGCGCACAACCC
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAAAAAGAGAAGGTAGAGAAAGCGGAATCTGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	CAGGTCTATCGGGCGATCAATAAAATCGGTCA
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GCGCACCGTTGCGTCGAAAAGGCGCTGGAGAT
GTGTTCCCCGCGCCAGCGGGGATAAACCG	TACGCTTACACAACGGGCGAATATTTTAACGG
GTGTTCCCCGCGCCAGCGGGGATAAACCG	GAACCCAATAGTGAAATACAGCATCATTTTTT
GTGTTCCCCGCGCCAGCGGGGATAAACCGACCTGGAGGCGAAAAAGGCGCTTCGACGTAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGGCCTATATCTCTAACCGCATCGGGCTGCGCGTGTTCCCCGCGCCAGCGGGGATAAACCGGG	GCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCGGG	GCAAATATAAATTCCAGCGTGCTTCATGAA
GTGTTCCCCGCGCCAGCGGGGATAAACCGCT	GCGTAGCGACCTTTGCTCTCAATTTCGTTG
GTGTTCCCCGCGCCAGCGGGGATAAACCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_000490440.1\|3919258_3920296_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	unknown	unknown	gnl\|CDD\|182299
NZ_CP049936.1\|WP_000517476.1\|3924056_3924368_+\|cell-division-protein-FtsB	unknown	unknown	gnl\|CDD\|179156
NZ_CP049936.1\|WP_000956458.1\|3909410_3909563_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	unknown	unknown	gnl\|CDD\|366840
NZ_CP049936.1\|WP_001090346.1\|3921457_3922885_+\|sulfate-adenylyltransferase-subunit-CysN	unknown	unknown	gnl\|CDD\|235349
NZ_CP049936.1\|WP_000144848.1\|3917104_3918028_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_CP049936.1\|WP_001246104.1\|3923539_3923863_+\|DUF3561-family-protein	unknown	unknown	gnl\|CDD\|371891
NZ_CP049936.1\|WP_001219242.1\|3925096_3925576_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
NZ_CP049936.1\|WP_000281423.1\|3916457_3917108_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
NZ_CP049936.1\|WP_000568943.1\|3925572_3926622_+\|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl\|CDD\|234884
NZ_CP049936.1\|WP_000085053.1\|3915729_3916476_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187776
NZ_CP049936.1\|WP_165746357.1\|3909756_3912456_+\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP049936.1\|WP_001295182.1\|3926602_3927364_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NZ_CP049936.1\|WP_000246136.1\|3924386_3925097_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
NZ_CP049936.1\|WP_000372108.1\|3920547_3921456_+\|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl\|CDD\|235375
NZ_CP049936.1\|WP_000029315.1\|3914112_3914649_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_CP049936.1\|WP_001084076.1\|3912553_3914116_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_CP049936.1\|WP_001173673.1\|3922884_3923490_+\|adenylyl-sulfate-kinase	unknown	unknown	gnl\|CDD\|179661
NZ_CP049936.1\|WP_000039843.1\|3908411_3909146_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
NZ_CP049936.1\|WP_000206429.1\|3914663_3915719_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
NZ_CP049936.1\|WP_000063176.1\|3918024_3918318_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_000490440.1\|3919258_3920296_-\|alkaline-phosphatase-isozyme-conversion-aminopeptidase	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
NZ_CP049936.1\|WP_000517476.1\|3924056_3924368_+\|cell-division-protein-FtsB	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
NZ_CP049936.1\|WP_000956458.1\|3909410_3909563_+\|type-I-toxin-antitoxin-system-Hok-family-toxin	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	8.32243e-12
NZ_CP049936.1\|WP_001090346.1\|3921457_3922885_+\|sulfate-adenylyltransferase-subunit-CysN	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NZ_CP049936.1\|WP_000144848.1\|3917104_3918028_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.03875e-156
NZ_CP049936.1\|WP_001246104.1\|3923539_3923863_+\|DUF3561-family-protein	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
NZ_CP049936.1\|WP_001219242.1\|3925096_3925576_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
NZ_CP049936.1\|WP_000281423.1\|3916457_3917108_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	1.48092e-91
NZ_CP049936.1\|WP_000568943.1\|3925572_3926622_+\|tRNA-pseudouridine(13)-synthase-TruD	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
NZ_CP049936.1\|WP_000085053.1\|3915729_3916476_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187776	cd09645, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.27305e-47
NZ_CP049936.1\|WP_165746357.1\|3909756_3912456_+\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.76236e-177
NZ_CP049936.1\|WP_001295182.1\|3926602_3927364_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
NZ_CP049936.1\|WP_000246136.1\|3924386_3925097_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.02844e-120
NZ_CP049936.1\|WP_000372108.1\|3920547_3921456_+\|sulfate-adenylyltransferase-subunit-CysD	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NZ_CP049936.1\|WP_000029315.1\|3914112_3914649_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	1.47989e-27
NZ_CP049936.1\|WP_001084076.1\|3912553_3914116_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	0
NZ_CP049936.1\|WP_001173673.1\|3922884_3923490_+\|adenylyl-sulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
NZ_CP049936.1\|WP_000039843.1\|3908411_3909146_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	7.99311e-138
NZ_CP049936.1\|WP_000206429.1\|3914663_3915719_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	8.2231e-155
NZ_CP049936.1\|WP_000063176.1\|3918024_3918318_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	2.35543e-65

>NZ_CP049936.1|WP_000063176.1|3918024_3918318_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ
>NZ_CP049936.1|WP_000144848.1|3917104_3918028_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKWNGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPTIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>NZ_CP049936.1|WP_000281423.1|3916457_3917108_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRITLHTAQLLPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFAPELRTGQSLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGRDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQLRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA
>NZ_CP049936.1|WP_000085053.1|3915729_3916476_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTIQMPKEVRKARYFSRREELSDPDLLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQGGLRHPVFPLYLGRKSHPLALPLAPLLLEGNASDVLRNAYQQYQDHFHDLKVSLPKLQDECWWEGEHDGLVVSKILRRRDVPLNRQQWLFGERTVNQGPWLSKEEPCTSQE
>NZ_CP049936.1|WP_000206429.1|3914663_3915719_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLSLLRKDRMAVDIAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFDVMNKQGSMKDVLDFICA
>NZ_CP049936.1|WP_000029315.1|3914112_3914649_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSIVKDGHKATLRKWHEELQAKRGNRASLRRSTTVNDVCLSEGFRSLLMQTHTLWKIEAQEWRFTALALVAAVAANVKAIDERQPFAAQLAAVMSEGRFTCLSAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIRIRWALEYYQAGDADNEQN
>NZ_CP049936.1|WP_001084076.1|3912553_3914116_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNAPSGGKGYRTGIRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQDDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHRFPLLLNKKEGQIPKLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADGLLSKWNKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>NZ_CP049936.1|WP_165746357.1|3909756_3912456_+|CRISPR-associated-helicase-Cas3'
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDNDEGIELIKHLSWYISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPTSSLSLFHSRFAFSDRQRIETKTLARFGKEGSSQRAGKALISTQVLEQSVDCDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDSPDEEWFGSAMRNSAYIYPDHGRIWLTQRVLRQQGAIQMPHSARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESVSLWLATCIDGVVKPYTTGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILVTDNESCGYSATEGLIGKVG
>NZ_CP049936.1|WP_000956458.1|3909410_3909563_+|type-I-toxin-antitoxin-system-Hok-family-toxin
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK
>NZ_CP049936.1|WP_000039843.1|3908411_3909146_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>NZ_CP049936.1|WP_000490440.1|3919258_3920296_-|alkaline-phosphatase-isozyme-conversion-aminopeptidase
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTASDNRKSWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSQGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRFDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>NZ_CP049936.1|WP_000372108.1|3920547_3921456_+|sulfate-adenylyltransferase-subunit-CysD
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>NZ_CP049936.1|WP_001090346.1|3921457_3922885_+|sulfate-adenylyltransferase-subunit-CysN
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARIDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>NZ_CP049936.1|WP_001173673.1|3922884_3923490_+|adenylyl-sulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>NZ_CP049936.1|WP_001246104.1|3923539_3923863_+|DUF3561-family-protein
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>NZ_CP049936.1|WP_000517476.1|3924056_3924368_+|cell-division-protein-FtsB
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>NZ_CP049936.1|WP_000246136.1|3924386_3925097_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQIPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>NZ_CP049936.1|WP_001219242.1|3925096_3925576_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>NZ_CP049936.1|WP_000568943.1|3925572_3926622_+|tRNA-pseudouridine(13)-synthase-TruD
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>NZ_CP049936.1|WP_001295182.1|3926602_3927364_+|5'/3'-nucleotidase-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: NZ_CP049936_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049936_10

4686226-4686361

Orphan

Consensus_repeat	Method
CTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049936_10

>merge|NZ_CP049936|10|4686226-4686361|CRISPRCasFinder
CTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCACTGAATGCCGGATGCGGCGTGAACGCCTTATCCGTCCTACGGTTCTGTGCTCGGATCTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA

>NZ_CP049936|10|8|4686226-4686361|CRISPRCasFinder
CTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA	CTGAATGCCGGATGCGGCGTGAACGCCTTATCCGTCCTACGGTTCTGTGCTCGGAT
CTTGTAGGCCTGATAAGACGCGCCAGCGTCGCATCAGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049936.1\|WP_001153547.1\|4675681_4676230_+\|colanic-acid-biosynthesis-acetyltransferase-WcaF	unknown	unknown	gnl\|CDD\|188523
NZ_CP049936.1\|WP_000704860.1\|4705044_4706211_+\|UDP-glucose-6-dehydrogenase	unknown	unknown	gnl\|CDD\|185017
NZ_CP049936.1\|WP_109556745.1\|4674919_4675666_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaE	unknown	unknown	gnl\|CDD\|182218
NZ_CP049936.1\|WP_086623715.1\|4688929_4690324_+\|colanic-acid-biosynthesis-protein-WcaM	unknown	unknown	gnl\|CDD\|182253
NZ_CP049936.1\|WP_086624443.1\|4703389_4704796_+\|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236453
NZ_CP049936.1\|WP_165746378.1\|4683271_4684666_+\|undecaprenyl-phosphate-glucose-phosphotransferase	unknown	unknown	gnl\|CDD\|182254
NZ_CP049936.1\|WP_106108382.1\|4687698_4688919_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaL	unknown	unknown	gnl\|CDD\|188520
NZ_CP049936.1\|WP_106108379.1\|4697748_4698714_+\|GDP-L-fucose-synthase	unknown	unknown	gnl\|CDD\|187550
NZ_CP049936.1\|WP_001752788.1\|4681765_4683136_+\|phosphomannomutase-CpsG	unknown	unknown	gnl\|CDD\|185312
NZ_CP049936.1\|WP_000183032.1\|4690498_4691392_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalF	unknown	unknown	gnl\|CDD\|182252
NZ_CP049936.1\|WP_086623717.1\|4686421_4687702_+\|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK	unknown	unknown	gnl\|CDD\|188521
NZ_CP049936.1\|WP_000107808.1\|4673691_4674909_+\|putative-colanic-acid-polymerase-WcaD	unknown	unknown	gnl\|CDD\|188525
NZ_CP049936.1\|WP_000828566.1\|4694666_4695419_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133038
NZ_CP049936.1\|WP_000043590.1\|4677379_4678345_+\|GDP-L-fucose-synthase	unknown	unknown	gnl\|CDD\|187550
NZ_CP049936.1\|WP_000725796.1\|4696622_4697744_+\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224014
NZ_CP049936.1\|WP_001752787.1\|4684667_4686146_+\|M-antigen-undecaprenyl-disphosphate-flippase	unknown	unknown	gnl\|CDD\|236697
NZ_CP049936.1\|WP_101291638.1\|4680048_4681485_+\|mannose-1-phosphate-guanyltransferase	unknown	unknown	gnl\|CDD\|185357
NZ_CP049936.1\|WP_001342585.1\|4678347_4678827_+\|GDP-mannose-mannosyl-hydrolase	unknown	unknown	gnl\|CDD\|237966
NZ_CP049936.1\|WP_106108383.1\|4676255_4677377_+\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224014
NZ_CP049936.1\|WP_000022655.1\|4693748_4694642_+\|alpha-1,2-fucosyltransferase	unknown	unknown	gnl\|CDD\|211387

Protein	Function_ID	Function_description	E-value
NZ_CP049936.1\|WP_001153547.1\|4675681_4676230_+\|colanic-acid-biosynthesis-acetyltransferase-WcaF	gnl\|CDD\|188523	TIGR04008, WcaF, colanic acid biosynthesis acetyltransferase WcaF. This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species. This acetyltransferase is believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit).	7.2871e-132
NZ_CP049936.1\|WP_000704860.1\|4705044_4706211_+\|UDP-glucose-6-dehydrogenase	gnl\|CDD\|185017	PRK15057, PRK15057, UDP-glucose 6-dehydrogenase; Provisional.	0
NZ_CP049936.1\|WP_109556745.1\|4674919_4675666_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaE	gnl\|CDD\|182218	PRK10063, PRK10063, colanic acid biosynthesis glycosyltransferase WcaE.	3.61145e-180
NZ_CP049936.1\|WP_086623715.1\|4688929_4690324_+\|colanic-acid-biosynthesis-protein-WcaM	gnl\|CDD\|182253	PRK10123, wcaM, putative colanic acid biosynthesis protein; Provisional.	0
NZ_CP049936.1\|WP_086624443.1\|4703389_4704796_+\|NADP-dependent-phosphogluconate-dehydrogenase	gnl\|CDD\|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NZ_CP049936.1\|WP_165746378.1\|4683271_4684666_+\|undecaprenyl-phosphate-glucose-phosphotransferase	gnl\|CDD\|182254	PRK10124, PRK10124, putative UDP-glucose lipid carrier transferase; Provisional.	0
NZ_CP049936.1\|WP_106108382.1\|4687698_4688919_+\|colanic-acid-biosynthesis-glycosyltransferase-WcaL	gnl\|CDD\|188520	TIGR04005, wcaL, colanic acid biosynthesis glycosyltransferase WcaL. This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.	0
NZ_CP049936.1\|WP_106108379.1\|4697748_4698714_+\|GDP-L-fucose-synthase	gnl\|CDD\|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.89655e-178
NZ_CP049936.1\|WP_001752788.1\|4681765_4683136_+\|phosphomannomutase-CpsG	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP049936.1\|WP_000183032.1\|4690498_4691392_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalF	gnl\|CDD\|182252	PRK10122, PRK10122, UTP--glucose-1-phosphate uridylyltransferase GalF.	0
NZ_CP049936.1\|WP_086623717.1\|4686421_4687702_+\|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK	gnl\|CDD\|188521	TIGR04006, wcaK, colanic acid biosynthesis pyruvyl transferase WcaK. This gene is the pyruvyl transferase involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.	0
NZ_CP049936.1\|WP_000107808.1\|4673691_4674909_+\|putative-colanic-acid-polymerase-WcaD	gnl\|CDD\|188525	TIGR04010, WcaD, putative colanic acid polymerase WcaD. This membrane protein is believed to function as the colanic acid repeating unit polymerase (in an analagous fashion to wzy proteins in O-antigen polymerization).	0
NZ_CP049936.1\|WP_000828566.1\|4694666_4695419_+\|glycosyltransferase	gnl\|CDD\|133038	cd04195, GT2_AmsE_like, GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis. AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	8.63113e-24
NZ_CP049936.1\|WP_000043590.1\|4677379_4678345_+\|GDP-L-fucose-synthase	gnl\|CDD\|187550	cd05239, GDP_FS_SDR_e, GDP-fucose synthetase, extended (e) SDRs. GDP-fucose synthetase (aka 3, 5-epimerase-4-reductase) acts in the NADP-dependent synthesis of GDP-fucose from GDP-mannose. Two activities have been proposed for the same active site: epimerization and reduction. Proteins in this subgroup are extended SDRs, which have a characteristic active site tetrad and an NADP-binding motif, [AT]GXXGXXG, that is a close match to the archetypical form. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NZ_CP049936.1\|WP_000725796.1\|4696622_4697744_+\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP049936.1\|WP_001752787.1\|4684667_4686146_+\|M-antigen-undecaprenyl-disphosphate-flippase	gnl\|CDD\|236697	PRK10459, PRK10459, MOP flippase family protein.	0
NZ_CP049936.1\|WP_101291638.1\|4680048_4681485_+\|mannose-1-phosphate-guanyltransferase	gnl\|CDD\|185357	PRK15460, cpsB, mannose-1-phosphate guanyltransferase; Provisional.	0
NZ_CP049936.1\|WP_001342585.1\|4678347_4678827_+\|GDP-mannose-mannosyl-hydrolase	gnl\|CDD\|237966	PRK15434, PRK15434, GDP-mannose mannosyl hydrolase.	1.77973e-118
NZ_CP049936.1\|WP_106108383.1\|4676255_4677377_+\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP049936.1\|WP_000022655.1\|4693748_4694642_+\|alpha-1,2-fucosyltransferase	gnl\|CDD\|211387	cd11301, Fut1_Fut2_like, Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.	6.05029e-55

>NZ_CP049936.1|WP_001752787.1|4684667_4686146_+|M-antigen-undecaprenyl-disphosphate-flippase
MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLLTVSLVIIALADTLSDFGIANSIIQRKEISHLELTTLYWLNVGLGLVVCVAVFLLSDAIGDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTVVSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTADSIINYLNTNLSTLVLARILGAGVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQDDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKWNSIIPVLQLLCMVGLLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMEGAIGVTLGFLLVQIINTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYALGIVLKGQLALGMLLAVQIAAGVLAFVVMIVLSRHPLVVEVKRQFCRSEKMKMLLRAG
>NZ_CP049936.1|WP_165746378.1|4683271_4684666_+|undecaprenyl-phosphate-glucose-phosphotransferase
MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATEFALLLQNWTLSVIFSAGLVAFNNDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKPGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVELDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY
>NZ_CP049936.1|WP_001752788.1|4681765_4683136_+|phosphomannomutase-CpsG
MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANNFPPVDETKRGRYQQINLRDAYVAHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREVLAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTLLTLLNE
>NZ_CP049936.1|WP_101291638.1|4680048_4681485_+|mannose-1-phosphate-guanyltransferase
MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLKGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAALAAKRHSPESDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGYIRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLDFIRVDEEAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISTHTAEGNVCHGDVINHKTENSYVYAESGLVTTVGVKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSVQMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGRV
>NZ_CP049936.1|WP_001342585.1|4678347_4678827_+|GDP-mannose-mannosyl-hydrolase
MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQFYGVWQHFYDDNFSGTDFTTHYVVLGFRFRVSEEELLLPDEQHDDYRWLTPDALLASDNVHANSRAYFLAEKRAGVPGL
>NZ_CP049936.1|WP_000043590.1|4677379_4678345_+|GDP-L-fucose-synthase
MSKQRIFIAGHRGMVGSAIKRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFRG
>NZ_CP049936.1|WP_106108383.1|4676255_4677377_+|GDP-mannose-4,6-dehydratase
MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGRGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES
>NZ_CP049936.1|WP_001153547.1|4675681_4676230_+|colanic-acid-biosynthesis-acetyltransferase-WcaF
MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKSLPANVVCRGNPAVVIRERVETE
>NZ_CP049936.1|WP_109556745.1|4674919_4675666_+|colanic-acid-biosynthesis-glycosyltransferase-WcaE
MLLSIITVAFRNLEGIVKTHASLAHLAQADDISFEWIVVDGGSNDGTREYLENLNGIYNLRFVSEPDNGIYDAMNKGIAMAQGKFALFLNSGDIFHQDAANFVRKLKMQKDNVMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKWRYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQILHVPGLWAELSWHLRQRTTSKTKALYNKV
>NZ_CP049936.1|WP_000107808.1|4673691_4674909_+|putative-colanic-acid-polymerase-WcaD
MSTSIRICSYLLLPLIYLLVNVKIAQLGESFPITIVTFLPVLLLLFLERISVKKLMIALGIGAGLTAFNYLFGQSLDASKYVTSTMLFVYIVIIIGMVWSIRFKTISPHNHRKILRFFYLVVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVLNFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGVMTFILFYLLEWAFQYLNKEAIKKKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGSSSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADVGKTIDNGLYLLIIYFSWFAVFLSLWYMGKVIKMIINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIVCPFILRKALNITR
>NZ_CP049936.1|WP_086623717.1|4686421_4687702_+|colanic-acid-biosynthesis-pyruvyl-transferase-WcaK
MKLLILGNHTCGNRGDSAILRGLLDAINILNPHAEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVLRRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGPFQDEQFNQLANYVFGHCDALIMRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAITLRELAPFDKRLGTTQQAYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLEMGKILGACELTVGTRLHSAIISMNFATPAIAINYEHKSAGIMQQLGLPEMSIDIRHLLDGSLQAMVADTLGQLPALNARLSEAVSRERQTGMQMVQSVLERIGEVK
>NZ_CP049936.1|WP_106108382.1|4687698_4688919_+|colanic-acid-biosynthesis-glycosyltransferase-WcaL
MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQNTHAAWTKYNLAARTRWLQDEPTGKVAKLRHRASHTLRGIHRKNTWQALNLKRYGAESRNLILSAICGQVATPFRADVFIAHFGPAGVTAAKLRELGVIRGKIATIFHGIDISSREVLNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKAPATPLEIISVARLTEKKGLHVAIEACRQLKEQGVAFRYRILGIGPWERRLRTLIEQYQLEDVVEMPGFKPSHEVKAMLDNADVFLLPSVTSADGDMEGIPVALMEAMAVGIPVVSTLHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDTDELAPVVKRAREKVEHDFNQQVINRELASLLQAL
>NZ_CP049936.1|WP_086623715.1|4688929_4690324_+|colanic-acid-biosynthesis-protein-WcaM
MPFKKLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHDWIASFKQAFSEGQMVVVPAGFVCDNINTGIFIPPGKTLHILGSLRGNGRGRFVLQDGSQVTGEEGGSMHNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMRNLTIDNLTVSHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLFMRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSVDIDRVNHHIVNVEKINFRLPERRE
>NZ_CP049936.1|WP_000183032.1|4690498_4691392_+|UTP--glucose-1-phosphate-uridylyltransferase-GalF
MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLELRVKRQLLAEVQSICPPGVTIMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE
>NZ_CP049936.1|WP_000022655.1|4693748_4694642_+|alpha-1,2-fucosyltransferase
MSIIRLQGGLGNQLFQFSFGYALSKINGTPLYFDISHYAENDDHGGYRLNNLQIPEEYLQYYTPKINNIYKFLVRGSRLYPEIFLFLGFCNEFHAYGYDFEYIAQKWKSKKYIGYWQSEHFFHKHILDLKEFFIPKNVSEQANLLAAKILESQSSLSIHIRRGDYIKNKTATLTHGVCSLEYYKKALNKIRDLAMIRDVFIFSDDIFWCKENIETLLSKKYNIYYSEDLSQEEDLWLMSLANHHIIANSSFSWWGAYLGTSASQIVIYPTPWYDITPKNTYIPIVNHWINVDKHSSC
>NZ_CP049936.1|WP_000828566.1|4694666_4695419_+|glycosyltransferase
MKRPYFSFLLCVNKDEGFLNDALESIINQDYSYEYEIIVIANNCDDNLWAYLNSVESDKLKIHRTNIGQLAFNLNYGANIARGEYIVRMDADDVSTPNRLKILEAAIQENNYPDVIGTSVYFISETGRIIKKYVPPLGEVKSALIKNPFVHPTVAIKKVSLFKIGGYLGGFQSEDNDLWIRMLRAHEFKLVNIDSVTLFYRINDHQTRGRVLPYAEVASYALREFLLKKRIKYFAALLINIGKALILPKR
>NZ_CP049936.1|WP_000725796.1|4696622_4697744_+|GDP-mannose-4,6-dehydratase
MKKKALITGITGQDGSYLAEFLLDKGYEVHGIKRRASLFNTNRIDHIYQDLHHEKQSFFLHYGDLTDSLNIVRLVQEIQPDEIYNLGAQSHVAVSFESPEYTADVDAIGTLRLLEAIRICGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKMYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRALANIAYGLEPCLYLGNMDALRDWGHAKDYVRMQWLMLQQETPDDFVIATGKQISVREFVRMAAANLGIELEFIGCGLKEVGVVKAIHGNEAPSVKIGDVIVQVDPRYFRPAEVETLLGYPEKAKIKLGWEPEITIEEMCKEMIRNDLNIAKQHSLLKLNGYDVSLSVEK
>NZ_CP049936.1|WP_106108379.1|4697748_4698714_+|GDP-L-fucose-synthase
MKMKKIYIAGHRGMVGSAIKRQLMKNSSVELIFRSSHELDLMNQDAVQKFFNTERIDEVYLAAAKVGGIYANNKYPADFIYNNILIQANVINSAHRAGVQKLLFLGSSCIYPKFAEQPIKEESLLCGSLEPTNEPYAIAKITGIKLCESYNRQYGRDYRSVMPTNLYGPNDNFHHENSHVLPALIRRFHEAKINNLPEVSVWGSGNALREFLHVDDMAAASIYIMNLPNERYKEYTKPECSHINVGSGKDYSIRQLAEMVAEITNYKGNIYFDSTKPDGTPRKLMSNERLSKLGWSPKIELYDGVKDTYQWFLNNIENIRK
>NZ_CP049936.1|WP_086624443.1|4703389_4704796_+|NADP-dependent-phosphogluconate-dehydrogenase
MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKAFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKDGVFHTEWLD
>NZ_CP049936.1|WP_000704860.1|4705044_4706211_+|UDP-glucose-6-dehydrogenase
MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVIGERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP049936_4	4.1\|2040359\|42\|NZ_CP049936\|PILER-CR	2040359-2040400	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	0	1.0
NZ_CP049936_3	3.1\|956229\|40\|NZ_CP049936\|CRISPRCasFinder	956229-956268	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	1	0.975
NZ_CP049936_4	4.2\|2040418\|40\|NZ_CP049936\|PILER-CR	2040418-2040457	40	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141028-141067	1	0.975
NZ_CP049936_1	1.1\|341826\|37\|NZ_CP049936\|CRISPRCasFinder	341826-341862	37	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113763	2	0.946
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	104-159	5	0.911
NZ_CP049936_8	8.16\|3902183\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902183-3902214	32	MG592456	Vibrio phage 1.081.O._10N.286.52.C2, partial genome	219798-219829	6	0.812
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP019314	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-2, complete sequence	71972-72003	6	0.812
NZ_CP049936_8	8.8\|3901695\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3901695-3901726	32	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	555773-555804	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	207611-207642	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	222835-222866	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	131047-131078	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	349369-349400	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	116770-116801	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	349371-349402	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	141808-141839	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	348980-349011	7	0.781
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	66681-66712	7	0.781
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	MN434096	Klebsiella phage JIPh_Kp127, complete genome	8414-8445	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	MK630230	Klebsiella phage Spivey, complete genome	1815-1846	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	MN434094	Klebsiella phage AmPh_EK80, complete genome	8419-8450	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	MG459987	Klebsiella phage Sugarland, complete genome	8643-8674	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	MT380195	Klebsiella phage KP_LZD_B01, complete genome	3481-3512	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	8404-8435	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	121617-121648	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	254266-254297	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	402616-402647	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	15995-16026	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	160650-160681	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	58852-58883	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NC_020385	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence	58853-58884	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP021062	Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence	376005-376036	8	0.75
NZ_CP049936_8	8.14\|3902061\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902061-3902092	32	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	146145-146176	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NC_010180	Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence	223698-223729	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	221508-221539	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP031072	Bacillus mycoides strain BPN401 plasmid pl395, complete sequence	147474-147505	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP040345	Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence	374123-374154	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	74049-74080	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	130803-130834	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	195225-195256	8	0.75
NZ_CP049936_8	8.19\|3902366\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902366-3902397	32	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	471476-471507	8	0.75
NZ_CP049936_8	8.20\|3902427\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902427-3902458	32	NZ_AP012556	Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence	152763-152794	8	0.75
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_CP038236	Leisingera sp. NJS201 plasmid unnamed2, complete sequence	2813-2844	8	0.75
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	353558-353589	8	0.75
NZ_CP049936_8	8.13\|3902000\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902000-3902031	32	HQ615693	Synechococcus phage S-CRM01, complete genome	2748-2779	9	0.719
NZ_CP049936_8	8.18\|3902305\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902305-3902336	32	NC_019699	Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence	59399-59430	9	0.719
NZ_CP049936_8	8.18\|3902305\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902305-3902336	32	MK962627	Achromobacter phage vB_AxyS_19-32_Axy06, complete genome	21335-21366	9	0.719
NZ_CP049936_8	8.20\|3902427\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902427-3902458	32	NZ_CP032828	Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence	161129-161160	9	0.719
NZ_CP049936_8	8.21\|3902488\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902488-3902519	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5210759-5210790	9	0.719
NZ_CP049936_8	8.21\|3902488\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902488-3902519	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	191956-191987	9	0.719
NZ_CP049936_8	8.21\|3902488\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902488-3902519	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	1498191-1498222	9	0.719
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	1036450-1036481	9	0.719
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	1555010-1555041	9	0.719
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	619383-619414	9	0.719
NZ_CP049936_8	8.25\|3902732\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902732-3902763	32	NC_017140	Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence	5097-5128	9	0.719
NZ_CP049936_8	8.27\|3902854\|32\|NZ_CP049936\|CRISPRCasFinder,CRT	3902854-3902885	32	MK249151	Blackfly microvirus SF02 isolate 049, complete genome	1908-1939	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP020898	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence	46007-46038	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	125777-125808	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP020950	Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence	134655-134686	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013587	Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence	68724-68755	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	166140-166171	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013598	Rhizobium sp. N741 plasmid pRspN741c, complete sequence	103164-103195	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	125386-125417	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013544	Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence	36015-36046	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	125777-125808	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013502	Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence	103085-103116	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013508	Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence	103164-103195	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013519	Rhizobium sp. N113 plasmid pRspN113b, complete sequence	103163-103194	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	125386-125417	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013492	Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence	103161-103192	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013497	Rhizobium sp. N621 plasmid pRspN621b, complete sequence	103161-103192	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP013592	Rhizobium sp. N871 plasmid pRspN871b, complete sequence	103085-103116	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	92301-92332	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NC_010996	Rhizobium etli CIAT 652 plasmid pB, complete sequence	100863-100894	9	0.719
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP034999	Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence	97248-97279	9	0.719
NZ_CP049936_9	9.3\|3918566\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918566-3918597	32	NZ_CP033139	Vibrio owensii strain 1700302 plasmid pVOWZ1, complete sequence	115828-115859	9	0.719
NZ_CP049936_9	9.3\|3918566\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918566-3918597	32	KY579375	Sulfolobus spindle-shaped virus 3 strain REY 15/4, complete genome	4523-4554	9	0.719
NZ_CP049936_9	9.3\|3918566\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918566-3918597	32	EU030939	Sulfolobus spindle-shaped virus 5, complete genome	8793-8824	9	0.719
NZ_CP049936_9	9.3\|3918566\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918566-3918597	32	JF412294	EBPR podovirus 1, partial sequence	3991-4022	9	0.719
NZ_CP049936_9	9.5\|3918688\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918688-3918719	32	AP014927	Ralstonia phage RSF1 DNA, complete genome	171005-171036	9	0.719
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	823434-823465	10	0.688
NZ_CP049936_8	8.24\|3902671\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902671-3902702	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	682589-682620	10	0.688
NZ_CP049936_8	8.26\|3902793\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902793-3902824	32	NZ_CP039902	Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence	33041-33072	10	0.688
NZ_CP049936_8	8.26\|3902793\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902793-3902824	32	NZ_CP039893	Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence	217865-217896	10	0.688
NZ_CP049936_8	8.26\|3902793\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902793-3902824	32	NZ_KY000025	Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence	208000-208031	10	0.688
NZ_CP049936_8	8.26\|3902793\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902793-3902824	32	NZ_KY000029	Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence	208000-208031	10	0.688
NZ_CP049936_8	8.27\|3902854\|32\|NZ_CP049936\|CRISPRCasFinder,CRT	3902854-3902885	32	NZ_CP038854	Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence	450688-450719	10	0.688
NZ_CP049936_9	9.2\|3918505\|32\|NZ_CP049936\|CRISPRCasFinder,CRT,PILER-CR	3918505-3918536	32	NZ_CP040452	Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence	1679246-1679277	10	0.688
NZ_CP049936_8	8.5\|3901512\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3901512-3901543	32	NZ_AP018282	Chondrocystis sp. NIES-4102 plasmid plasmid1 DNA, complete genome	109485-109516	11	0.656
NZ_CP049936_8	8.18\|3902305\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902305-3902336	32	NZ_KY000056	Agrobacterium vitis strain Tun201 plasmid pTi_Tun201, complete sequence	141208-141239	11	0.656
NZ_CP049936_8	8.18\|3902305\|32\|NZ_CP049936\|PILER-CR,CRISPRCasFinder,CRT	3902305-3902336	32	NZ_KY000060	Agrobacterium tumefaciens strain CFBP2407 plasmid pTi_CFBP2407, complete sequence	186805-186836	11	0.656
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4157-4212	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229185-229240	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229286-229341	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4156-4211	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239679-239734	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239780-239835	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	115797-115852	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4156-4211	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230591-230646	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230692-230747	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4156-4211	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211561-211616	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211662-211717	11	0.804
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229084-229139	12	0.786
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239578-239633	12	0.786
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230490-230545	12	0.786
NZ_CP049936_10	10.1\|4686266\|56\|NZ_CP049936\|CRISPRCasFinder	4686266-4686321	56	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211460-211515	12	0.786

1. spacer 4.1|2040359|42|NZ_CP049936|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 0, identity: 1.0

tgtcacacgcagataaatccaactttcaatattgttaagttc	CRISPR spacer
tgtcacacgcagataaatccaactttcaatattgttaagttc	Protospacer
******************************************

2. spacer 3.1|956229|40|NZ_CP049936|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 1, identity: 0.975

gcgctgcgggtcattcttgaaattccccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
************************ ***************

3. spacer 4.2|2040418|40|NZ_CP049936|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 1, identity: 0.975

catggcgtagcaaaaagaaattttcaatattgctttatgg	CRISPR spacer
catggcgtagaaaaaagaaattttcaatattgctttatgg	Protospacer
********** *****************************

4. spacer 1.1|341826|37|NZ_CP049936|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.946

cggacgcag-atggtgcgttcaattggactcgaaccaa	CRISPR spacer
-agacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
 .******* ****************************

5. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 5, identity: 0.911

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat	CRISPR spacer
acgatcgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcgggt	Protospacer
 .** .************************************************.*

6. spacer 8.16|3902183|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MG592456 (Vibrio phage 1.081.O._10N.286.52.C2, partial genome) position: , mismatch: 6, identity: 0.812

attcttgatcacgcttttaccgaagt--aatggt	CRISPR spacer
attgttgatcacgcttttactgaagttcgacg--	Protospacer
*** ****************.*****  .*.*

7. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019314 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-2, complete sequence) position: , mismatch: 6, identity: 0.812

ccaccgttttcgcccaccagggcgcacaaccc-	CRISPR spacer
gcaccgttctcgcccaacagggcg-acaatctc	Protospacer
 *******.******* ******* ****.*.

8. spacer 8.8|3901695|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

-gtctgtgatggcctgctcgtgagtccgcggcg	CRISPR spacer
cgcgtg-gatggcctgctcgtcagttcgcgcct	Protospacer
 *. ** ************** ***.**** *

9. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

10. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

11. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

12. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

13. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

14. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

15. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

16. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.781

atccggctatatctttgagcattacagaaata	CRISPR spacer
ttatagctatatctttgtgcattagagaaatc	Protospacer
 * ..************ ****** ******

17. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.781

ccaccgttttcgcccaccagggcgcacaaccc-	CRISPR spacer
ccaccgtcttcgccgaccagggca-acgtcctc	Protospacer
*******.****** ********. **. **.

18. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

19. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MK630230 (Klebsiella phage Spivey, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

20. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MN434094 (Klebsiella phage AmPh_EK80, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

21. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MG459987 (Klebsiella phage Sugarland, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

22. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

23. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

24. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 8, identity: 0.75

atccggctatatctttgagcattacagaaata	CRISPR spacer
atccggctatgcctttgagcattgccgtgact	Protospacer
**********..***********.* * .*.

25. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcttacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

26. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

27. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

28. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

29. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

30. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_020385 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

31. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021062 (Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

32. spacer 8.14|3902061|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ctattgctttcgtacagattttcagtggtgct	CRISPR spacer
tatttgctttcctacagattttctgtcttgtt	Protospacer
.  ******** *********** **  **.*

33. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_010180 (Bacillus mycoides KBAB4 plasmid pBWB401, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

34. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

35. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031072 (Bacillus mycoides strain BPN401 plasmid pl395, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

36. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040345 (Bacillus albus strain DLOU-Yingkou plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

37. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

38. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

39. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

40. spacer 8.19|3902366|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 8, identity: 0.75

cgttctg---aatccgatattcttcagcaccttca	CRISPR spacer
---tccaaacaatccgatattcttcctcaccttct	Protospacer
   **..   ***************  *******

41. spacer 8.20|3902427|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP012556 (Mycobacterium avium subsp. hominissuis TH135 plasmid pMAH135, complete sequence) position: , mismatch: 8, identity: 0.75

agcgtcaatcagcgcgtctatcgcgtcacttt	CRISPR spacer
ggcgtcaatgagcgcgtcgatcgcggcgggat	Protospacer
.******** ******** ****** *.   *

42. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038236 (Leisingera sp. NJS201 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tcgagcccgatcatcggcatcagcagttccgg	Protospacer
.**********.******** ***..* * *.

43. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 8, identity: 0.75

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tcgaccccgattatcgggatgagctcggcgtg	Protospacer
.*** ************ ******   *** .

44. spacer 8.13|3902000|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to HQ615693 (Synechococcus phage S-CRM01, complete genome) position: , mismatch: 9, identity: 0.719

atccggctatatctttgagcattacagaaata	CRISPR spacer
gcctcaatatatcattgagcaatacagaaatt	Protospacer
..*. . ****** ******* *********

45. spacer 8.18|3902305|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_019699 (Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence) position: , mismatch: 9, identity: 0.719

cggcgttccgtgcggcaattggaatcacacca	CRISPR spacer
agagaatccctgcggcaattggaatcccagcc	Protospacer
 *. . *** **************** ** *

46. spacer 8.18|3902305|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to MK962627 (Achromobacter phage vB_AxyS_19-32_Axy06, complete genome) position: , mismatch: 9, identity: 0.719

cggcgttccgtgcggcaattggaatcacacca	CRISPR spacer
cggcgttccgtccggcaactggatgcccttgt	Protospacer
*********** ******.****  * * .

47. spacer 8.20|3902427|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032828 (Sphingomonas sp. YZ-8 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

agcgtcaatcagcgcgtctatcgcgtcacttt	CRISPR spacer
gaactcaatcagcgcgttcatcgcgtcgcgat	Protospacer
..  *************..********.*  *

48. spacer 8.21|3902488|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.719

atttgggggtatgagagcgccgagccgttcgg	CRISPR spacer
gtcgaacggtatgcgggcgccgagccgttcga	Protospacer
.*. .. ****** *.***************.

49. spacer 8.21|3902488|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

atttgggggtatgagagcgccgagccgttcgg	CRISPR spacer
aaacgttcgtatgagcgcgccgagtcgttcgt	Protospacer
*  .*   ******* ********.******

50. spacer 8.21|3902488|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 9, identity: 0.719

atttgggggtatgagagcgccgagccgttcgg	CRISPR spacer
aaacgttcgtatgagcgcgccgagtcgttcgt	Protospacer
*  .*   ******* ********.******

51. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
tgaattaggattatcgacatgagcgatacgga	Protospacer
. .* .  ********.**********.****

52. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gcgagcccgatcatcggcatgggcttcgagct	Protospacer
 **********.*********.**  .* *

53. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 9, identity: 0.719

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gcgagcccgatcatcggcatgggcttcgagct	Protospacer
 **********.*********.**  .* *

54. spacer 8.25|3902732|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_017140 (Bacillus megaterium WSH-002 plasmid WSH-002_p2, complete sequence) position: , mismatch: 9, identity: 0.719

tcgaagaagaaagggaaataatgcgaggaacg	CRISPR spacer
atggagaagaaagggaaacaaagcgagcgcgg	Protospacer
 .*.**************.** ***** .  *

55. spacer 8.27|3902854|32|NZ_CP049936|CRISPRCasFinder,CRT matches to MK249151 (Blackfly microvirus SF02 isolate 049, complete genome) position: , mismatch: 9, identity: 0.719

cgcgagagccagcaaaacgccagggcacaaaa	CRISPR spacer
gccatgtcccaacaaaacgccagggaacaaat	Protospacer
  *. *  ***.************* *****

56. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020898 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRetBra5b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

57. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

58. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020950 (Rhizobium sp. CIAT894 plasmid pRheCIAT894c, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

59. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013587 (Rhizobium phaseoli strain N161 plasmid pRphaN161b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

60. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
gcaccgttttcgccgatcagggcggtgacctt	Protospacer
 ************* *.*******   * *..

61. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013598 (Rhizobium sp. N741 plasmid pRspN741c, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

62. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

63. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013544 (Rhizobium phaseoli strain R620 plasmid pRphaR620b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

64. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

65. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013502 (Rhizobium esperanzae strain N561 plasmid pRspN561b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

66. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013508 (Rhizobium sp. N1341 plasmid pRspN1341c, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

67. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013519 (Rhizobium sp. N113 plasmid pRspN113b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

68. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

69. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013492 (Rhizobium sp. N6212 plasmid pRspN6212b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

70. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013497 (Rhizobium sp. N621 plasmid pRspN621b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

71. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013592 (Rhizobium sp. N871 plasmid pRspN871b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

72. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

73. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NC_010996 (Rhizobium etli CIAT 652 plasmid pB, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

74. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034999 (Rhizobium acidisoli strain FH23 plasmid pRapFH23a, complete sequence) position: , mismatch: 9, identity: 0.719

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
cgtccgcgttcgcccaccagggcgcagacgat	Protospacer
*  ***. ****************** *   .

75. spacer 9.3|3918566|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033139 (Vibrio owensii strain 1700302 plasmid pVOWZ1, complete sequence) position: , mismatch: 9, identity: 0.719

gaaaaagagaaggtagagaaagcggaatctgg	CRISPR spacer
gaaaaagagaatgtagaggaagcgtttttctt	Protospacer
*********** ******.*****   *..

76. spacer 9.3|3918566|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to KY579375 (Sulfolobus spindle-shaped virus 3 strain REY 15/4, complete genome) position: , mismatch: 9, identity: 0.719

gaaaaagagaaggtagagaaagcggaatctgg	CRISPR spacer
gacaaagagaaagtagagaaagcgattttctt	Protospacer
** ********.************.  *..

77. spacer 9.3|3918566|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to EU030939 (Sulfolobus spindle-shaped virus 5, complete genome) position: , mismatch: 9, identity: 0.719

gaaaaagagaaggtagagaaagcggaatctgg	CRISPR spacer
gacaaagagaaagtagagaaagcgattttctt	Protospacer
** ********.************.  *..

78. spacer 9.3|3918566|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to JF412294 (EBPR podovirus 1, partial sequence) position: , mismatch: 9, identity: 0.719

gaaaaagagaaggtagagaaagcggaatctgg	CRISPR spacer
gaaaaagagaaggccgagaaagcagcgaaggc	Protospacer
*************. ********.* .   *

79. spacer 9.5|3918688|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to AP014927 (Ralstonia phage RSF1 DNA, complete genome) position: , mismatch: 9, identity: 0.719

gcgcaccgttgcgtcgaaaaggcgctggagat	CRISPR spacer
cagacccgtttcgtcgaacaggcgctggcgtg	Protospacer
  *  ***** ******* ********* *

80. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gttgcggcgatcatcggcatgggcgatgcgta	Protospacer
 . .   ****.*********.******** *

81. spacer 8.24|3902671|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 10, identity: 0.688

ccgagcccgattatcggcatgagcgatgcgga	CRISPR spacer
gttgcggcgatcatcggcatgggcgatgcgta	Protospacer
 . .   ****.*********.******** *

82. spacer 8.26|3902793|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039902 (Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

83. spacer 8.26|3902793|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039893 (Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

84. spacer 8.26|3902793|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000025 (Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

85. spacer 8.26|3902793|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000029 (Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence) position: , mismatch: 10, identity: 0.688

tattacgcgccagcaatgctgacagcggcaaa	CRISPR spacer
agcatggcgccagcaatggcgacagcggccag	Protospacer
 ..   ************ .********* *.

86. spacer 8.27|3902854|32|NZ_CP049936|CRISPRCasFinder,CRT matches to NZ_CP038854 (Pantoea vagans strain LMG 24199 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cgcgagagccagcaaaacgccagggcacaaaa	CRISPR spacer
ggaaggagcctgcaaagcgccagggcaccggt	Protospacer
 * ..***** *****.*********** ..

87. spacer 9.2|3918505|32|NZ_CP049936|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040452 (Halomonas sp. PA16-9 plasmid p_unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ccaccgttttcgcccaccagggcgcacaaccc	CRISPR spacer
ccaccgtattcgccaaccagggcggcagggaa	Protospacer
******* ****** *********   ..

88. spacer 8.5|3901512|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018282 (Chondrocystis sp. NIES-4102 plasmid plasmid1 DNA, complete genome) position: , mismatch: 11, identity: 0.656

acggcgtggattgagggacgggtatttggtcc	CRISPR spacer
gcggagtggattgaggtacgggtaaagaagga	Protospacer
.*** *********** *******   ..

89. spacer 8.18|3902305|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000056 (Agrobacterium vitis strain Tun201 plasmid pTi_Tun201, complete sequence) position: , mismatch: 11, identity: 0.656

cggcgttccgtgcggcaattggaatcacacca	CRISPR spacer
ttttcttccgtgcggcaattcgtatcacggat	Protospacer
.  . *************** * *****.

90. spacer 8.18|3902305|32|NZ_CP049936|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000060 (Agrobacterium tumefaciens strain CFBP2407 plasmid pTi_CFBP2407, complete sequence) position: , mismatch: 11, identity: 0.656

cggcgttccgtgcggcaattggaatcacacca	CRISPR spacer
ttttcttccgtgcggcaattcgtatcacggat	Protospacer
.  . *************** * *****.

91. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acaactgccggatgcggcgtgaacgccttatccgtcctaccgttcag-gcacaagtt	Protospacer
 ..* *********************************** **** * ** *...*

92. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgcgggaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

93. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacgggt-ggcgcgagaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

94. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acaactgccggatgcggcgtgaacgccttatccgtcctaccgttcag-gcacaagtt	Protospacer
 ..* *********************************** **** * ** *...*

95. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgcgggaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

96. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacgggt-ggcgcgagaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

97. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acaactgccggatgcggcgtgaacgccttatccgtcctaccgttcag-gcacaagtt	Protospacer
 ..* *********************************** **** * ** *...*

98. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acaactgccggatgcggcgtgaacgccttatccgtcctaccgttcag-gcacaagtt	Protospacer
 ..* *********************************** **** * ** *...*

99. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgcgggaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

100. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacgggt-ggcgcgagaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

101. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acaactgccggatgcggcgtgaacgccttatccgtcctaccgttcag-gcacaagtt	Protospacer
 ..* *********************************** **** * ** *...*

102. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgcgggaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

103. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.804

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacgggt-ggcgcgagaatt	Protospacer
 .** ***************************** ******* *  *.**  *.**

104. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.786

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgtgagaatt	Protospacer
 .** ***************************** ******* *  *.*.  *.**

105. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.786

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgtgagaatt	Protospacer
 .** ***************************** ******* *  *.*.  *.**

106. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.786

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgtgagaatt	Protospacer
 .** ***************************** ******* *  *.*.  *.**

107. spacer 10.1|4686266|56|NZ_CP049936|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.786

ctgaatgccggatgcggcgtgaacgccttatccgtcctacggttctgtgctcggat-	CRISPR spacer
acgactgccggatgcggcgtgaacgccttatccggcctacggat-ggcgtgagaatt	Protospacer
 .** ***************************** ******* *  *.*.  *.**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1440226 : 1498202

Enterobacteria_phage(58.62%)

terminase,tail,lysis,portal,head,integrase,capsid,tRNA,protease

attL 1439758:1439804|attR 1487995:1488041

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1439758:1439804	attL	NA	NA	NA	NA
WP_001201825.1\|1440226_1441180_+\|protease	omptin family outer membrane protease OmpT	NA	NA	NA	NA
WP_071790202.1\|1441605_1442850_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000937502.1\|1443033_1443339_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	2.8e-12	76.5
WP_072022911.1\|1443403_1444063_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_120795384.1\|1444428_1444542_+	Rac prophage; protein YnaM	A0A1C9IHU6	Salmonella_phage	8.4e-07	80.6
WP_000836768.1\|1444610_1444844_+	cold shock protein YdfK	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
WP_000078177.1\|1445160_1445751_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
WP_000885616.1\|1445848_1446424_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	6.5e-103	95.3
WP_165746314.1\|1446423_1449495_-\|tail	phage tail protein	U5N099	Enterobacteria_phage	8.6e-69	55.4
WP_165746315.1\|1449559_1450159_-	Ail/Lom family outer membrane beta-barrel protein	A5LH44	Enterobacteria_phage	1.2e-107	96.5
WP_165746316.1\|1450229_1453727_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	97.2
WP_071704046.1\|1453787_1454420_-\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.9e-95	98.6
WP_165746317.1\|1454356_1455100_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	1.0e-145	96.0
WP_001152639.1\|1455105_1455804_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
WP_000847379.1\|1455803_1456133_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
WP_000840244.1\|1456129_1458691_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	99.5
WP_000459457.1\|1458683_1459118_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
WP_000479153.1\|1459099_1459522_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	6.7e-73	100.0
WP_001401350.1\|1459537_1460278_-\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	5.0e-132	99.2
WP_000683105.1\|1460285_1460681_-\|tail	tail protein	A0A0K2FIF4	Enterobacteria_phage	1.0e-70	100.0
WP_000975081.1\|1460677_1461256_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	99.5
WP_000785282.1\|1461267_1461621_-\|tail	tail attachment protein	A0A2R9YJJ5	Escherichia_phage	6.4e-61	97.4
WP_000158875.1\|1461632_1462028_-	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	1.1e-58	95.5
WP_000063236.1\|1462069_1463095_-\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	1.8e-188	97.7
WP_001358225.1\|1463150_1463483_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.5e-54	98.2
WP_000123248.1\|1463492_1464812_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.8e-233	98.6
WP_001358226.1\|1464792_1466394_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	8.8e-312	99.8
WP_000198149.1\|1466390_1466597_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_001027292.1\|1466593_1468519_-\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	100.0
WP_000453580.1\|1468493_1469039_-	DNA-packaging protein	A0A0K2FIG2	Enterobacteria_phage	2.8e-95	100.0
WP_165746318.1\|1469428_1469623_+	DUF3950 domain-containing protein	A0A0K2FIR8	Escherichia_phage	8.2e-26	95.2
WP_000738421.1\|1469983_1470277_+	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	5.9e-44	90.7
WP_001228695.1\|1470367_1470550_-\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_001135277.1\|1470766_1471264_-	lysozyme RrrD	M1FJA0	Enterobacteria_phage	5.4e-90	97.0
WP_000839596.1\|1471263_1471479_-\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000737267.1\|1472051_1473149_+	porin	Q1MVN1	Enterobacteria_phage	1.6e-155	76.5
WP_074468224.1\|1473328_1473712_-	antitermination protein QuuD	A0A088CD47	Shigella_phage	5.2e-56	84.2
WP_097551430.1\|1473797_1473938_-	YlcG family protein	K7PHH3	Enterobacteria_phage	6.5e-09	69.8
WP_001635801.1\|1473934_1474297_-	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	2.5e-60	96.6
WP_032176362.1\|1474293_1474584_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	6.7e-48	95.8
WP_000224907.1\|1474576_1474747_-	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_165746319.1\|1474746_1475202_-	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	3.7e-61	68.2
WP_072097617.1\|1475198_1475300_-	hypothetical protein	NA	NA	NA	NA
WP_000520500.1\|1475423_1475825_-	hypothetical protein	NA	NA	NA	NA
WP_001038620.1\|1475803_1476220_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_053901423.1\|1476519_1477128_-	hypothetical protein	Q9T1Q5	Acyrthosiphon_pisum_secondary_endosymbiont_phage	1.5e-33	67.3
WP_000152742.1\|1477880_1478228_+	hypothetical protein	NA	NA	NA	NA
WP_089632318.1\|1478432_1479134_-	Replication protein P	M1FJ72	Enterobacteria_phage	3.8e-129	99.1
WP_053274831.1\|1479130_1480060_-	replication protein	M1FN81	Enterobacteria_phage	8.0e-111	67.6
WP_001182872.1\|1480146_1480686_-	hypothetical protein	M9NZI6	Enterobacteria_phage	5.2e-62	66.7
WP_001067459.1\|1480767_1480998_-	helix-turn-helix domain-containing protein	A0A2H4FNF3	Salmonella_phage	8.5e-22	68.0
WP_046083248.1\|1481036_1481792_+	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.4e-92	75.0
WP_052728133.1\|1481965_1482814_+	DUF3800 domain-containing protein	A5X9G9	Aeromonas_virus	2.7e-57	45.3
WP_023148105.1\|1483210_1483501_+	hypothetical protein	K7P6H3	Enterobacteria_phage	5.0e-27	85.1
WP_000995439.1\|1483576_1483873_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.6e-49	100.0
WP_000100847.1\|1483878_1484664_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000186776.1\|1484660_1485341_+	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	6.7e-131	98.7
WP_000149544.1\|1485337_1485520_+	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	6.9e-27	96.7
WP_000548530.1\|1485492_1485684_+	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_077252933.1\|1485694_1485982_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	5.6e-47	98.9
WP_000763385.1\|1486074_1486293_+	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	7.5e-36	100.0
WP_000488407.1\|1486340_1486619_+	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.9e-48	97.8
WP_000051902.1\|1486817_1487981_+\|integrase	site-specific integrase	A0A088CD23	Shigella_phage	3.0e-200	86.6
WP_000805428.1\|1488315_1488948_+	fimbria biosynthesis transcriptional regulator FimZ	NA	NA	NA	NA
1487995:1488041	attR	NA	NA	NA	NA
WP_001250422.1\|1488950_1489466_-	fimbria assembly protein	NA	NA	NA	NA
WP_165746320.1\|1489476_1490484_-	type 1 fimbrin D-mannose specific adhesin FimH	NA	NA	NA	NA
WP_001306954.1\|1490496_1493106_-	fimbrial biogenesis usher protein	NA	NA	NA	NA
WP_000988375.1\|1493136_1493829_-	type 1 fimbria chaperone FimC	NA	NA	NA	NA
WP_001315309.1\|1494048_1494591_-	type 1 fimbrial protein subunit FimA	NA	NA	NA	NA
WP_000729154.1\|1495071_1495938_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.7e-30	37.5
WP_000190288.1\|1495939_1496152_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_001143552.1\|1496259_1496781_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_000912345.1\|1496816_1498202_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.9e-45	34.8

DBSCAN-SWA_2

1769284 : 1834218

Enterobacteria_phage(15.79%)

plate,integrase,transposase

attL 1778294:1778310|attR 1798349:1798365

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164708657.1\|1769284_1770498_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	5.1e-166	98.0
WP_106883827.1\|1770658_1772764_-	injection protein	A0A2I7QQN9	Vibrio_phage	1.2e-90	37.0
WP_001577239.1\|1772763_1774185_-	phage DNA ejection protein	B6SCW4	Bacteriophage	3.7e-123	53.0
WP_000909175.1\|1774184_1774862_-	hypothetical protein	Q2A0B2	Sodalis_phage	9.2e-56	71.6
WP_000420674.1\|1774855_1775317_-	DUF2824 family protein	Q2A0B3	Sodalis_phage	2.9e-61	72.2
WP_001018524.1\|1775333_1775495_-	hypothetical protein	NA	NA	NA	NA
WP_001244106.1\|1776079_1778836_-	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	1.8e-299	57.3
1778294:1778310	attL	NA	NA	NA	NA
WP_001208877.1\|1778822_1779194_-	hypothetical protein	NA	NA	NA	NA
WP_000628966.1\|1779186_1779528_-	hypothetical protein	A0A1B5FPL8	Escherichia_phage	2.5e-33	61.5
WP_001812772.1\|1779538_1780141_-	hypothetical protein	A0A286S1S7	Klebsiella_phage	3.3e-25	36.3
WP_000181940.1\|1780133_1780355_-	hypothetical protein	NA	NA	NA	NA
WP_001024679.1\|1780351_1780615_-	hypothetical protein	NA	NA	NA	NA
WP_001065661.1\|1780611_1780806_-	hypothetical protein	NA	NA	NA	NA
WP_001812770.1\|1780798_1781866_-	ash family protein	NA	NA	NA	NA
WP_000476150.1\|1781859_1782042_-	DUF4222 domain-containing protein	NA	NA	NA	NA
WP_021530316.1\|1782034_1782868_-	hypothetical protein	G9L6G1	Escherichia_phage	5.3e-21	47.5
WP_000412531.1\|1782880_1783312_-	hypothetical protein	A0A1W6JPH9	Morganella_phage	2.3e-28	49.7
WP_000035054.1\|1783311_1783515_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	4.7e-08	50.9
WP_001577236.1\|1783942_1785157_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	1.3e-132	56.5
WP_000893255.1\|1785512_1786766_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.8e-96	47.2
WP_001285288.1\|1786777_1787881_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000749882.1\|1788168_1789224_+	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	1.3e-117	60.6
WP_000174677.1\|1789262_1789664_-	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000189543.1\|1789721_1790966_-	esterase FrsA	NA	NA	NA	NA
WP_001291990.1\|1791057_1791516_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_001293016.1\|1791776_1793234_+	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_000602112.1\|1793290_1793905_-	peptide chain release factor H	NA	NA	NA	NA
WP_000528869.1\|1793901_1795041_-	RNA ligase RtcB family protein	A0A222ZMP7	Mycobacterium_phage	2.0e-31	31.7
WP_001059855.1\|1795286_1795739_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001226183.1\|1795735_1796791_-	DNA polymerase IV	NA	NA	NA	NA
WP_000207575.1\|1796861_1797647_-	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001296890.1\|1797591_1799331_+	flagellar type III secretion system protein FlhA	NA	NA	NA	NA
1798349:1798365	attR	NA	NA	NA	NA
WP_000598760.1\|1799435_1799714_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_001030483.1\|1799706_1800063_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_000543895.1\|1800119_1800893_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.2e-19	37.7
WP_000729704.1\|1801078_1801339_+	type II toxin-antitoxin system antitoxin DinJ	NA	NA	NA	NA
WP_000615976.1\|1801341_1801620_+	type II toxin-antitoxin system mRNA interferase toxin YafQ	NA	NA	NA	NA
WP_001225679.1\|1801775_1802516_+	murein L,D-transpeptidase	NA	NA	NA	NA
WP_000333380.1\|1802486_1803254_-	class II glutamine amidotransferase	NA	NA	NA	NA
WP_000284050.1\|1803459_1804038_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_000973081.1\|1804277_1806722_+	acyl-CoA dehydrogenase FadE	NA	NA	NA	NA
WP_000532698.1\|1806764_1807238_-	C-lysozyme inhibitor	NA	NA	NA	NA
WP_001118038.1\|1807391_1808162_+	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_122985282.1\|1810649_1810835_+	hypothetical protein	NA	NA	NA	NA
WP_001513053.1\|1810749_1811013_-	hypothetical protein	NA	NA	NA	NA
WP_071524591.1\|1814954_1815197_-	DUF3969 family protein	NA	NA	NA	NA
WP_000960006.1\|1815414_1815867_-	hypothetical protein	NA	NA	NA	NA
WP_001101835.1\|1817210_1817603_-	hypothetical protein	NA	NA	NA	NA
WP_165746325.1\|1817580_1821813_-	RHS repeat protein	A0A2H4JHK7	uncultured_Caudovirales_phage	3.8e-22	43.1
WP_001142958.1\|1824237_1824756_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000037397.1\|1825452_1825953_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_000123970.1\|1825987_1826212_+	hypothetical protein	NA	NA	NA	NA
WP_000056978.1\|1826262_1827738_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000611742.1\|1827744_1828158_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000393844.1\|1828161_1830012_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_000348793.1\|1829975_1831058_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_001113703.1\|1831082_1832363_+	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_001080149.1\|1832359_1832884_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000246416.1\|1832886_1834218_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_3

3978022 : 4072965

101

Salmonella_phage(66.1%)

tail,plate,lysis,transposase,portal,head,integrase,capsid,tRNA,terminase

attL 4024353:4024399|attR 4061692:4061738

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000047176.1\|3978022_3980653_+\|tRNA	alanine--tRNA ligase	A0A2K9L1X7	Tupanvirus	5.5e-80	38.6
WP_000906486.1\|3980887_3981073_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	4.9e-12	66.7
WP_000273309.1\|3982664_3983231_+	fructose-1-phosphate/6-phosphogluconate phosphatase	NA	NA	NA	NA
WP_001287457.1\|3983227_3983656_+	DedA family protein	NA	NA	NA	NA
WP_000611802.1\|3983728_3985285_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_001130211.1\|3985434_3985950_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_001295176.1\|3986013_3987552_-	multidrug efflux MFS transporter permease subunit EmrB	NA	NA	NA	NA
WP_001295175.1\|3987568_3988741_-	multidrug efflux MFS transporter periplasmic adaptor subunit EmrA	NA	NA	NA	NA
WP_000378442.1\|3988867_3989398_-	multidrug efflux transporter EmrAB transcriptional repressor EmrR	NA	NA	NA	NA
WP_048265082.1\|3989368_3989470_+	hypothetical protein	NA	NA	NA	NA
WP_000119763.1\|3989488_3989824_-	L-valine transporter subunit YgaH	NA	NA	NA	NA
WP_000445658.1\|3989813_3990551_-	L-valine exporter subunit YgaZ	NA	NA	NA	NA
WP_000165699.1\|3990674_3991859_-	MFS transporter	NA	NA	NA	NA
WP_001216527.1\|3992149_3993142_-	glycine betaine/L-proline ABC transporter substrate-binding protein ProX	NA	NA	NA	NA
WP_000774978.1\|3993198_3994263_-	glycine betaine/L-proline ABC transporter permease ProW	NA	NA	NA	NA
WP_000985494.1\|3994255_3995458_-	glycine betaine/L-proline ABC transporter ATP-binding protein ProV	G3M9Y6	Bacillus_virus	4.9e-28	39.4
WP_000777969.1\|3995812_3996772_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	3.5e-133	71.8
WP_000246542.1\|3996781_3998926_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.8e-196	48.4
WP_000080944.1\|3998898_3999309_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.7e-18	44.4
WP_001223235.1\|3999305_3999551_-	glutaredoxin-like protein NrdH	Q5K5J3	Oenococcus_phage	2.4e-06	35.3
WP_001295174.1\|3999798_4000128_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_000281320.1\|4000279_4000624_+	YgaC family protein	NA	NA	NA	NA
WP_000492656.1\|4000660_4001110_-	L-alanine exporter AlaE	NA	NA	NA	NA
WP_000115383.1\|4001777_4002182_+	DNA-binding protein StpA	NA	NA	NA	NA
WP_001229470.1\|4002228_4002753_-	thiosulfate sulfurtransferase YgaP	NA	NA	NA	NA
WP_000137280.1\|4002762_4003062_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000508177.1\|4003244_4003403_+	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_000522424.1\|4003486_4003936_+	potassium binding protein Kbp	A0A090DBR9	Clostridium_phage	2.0e-06	39.5
WP_000156811.1\|4003936_4004599_-	DNA-binding transcriptional regulator CsiR	NA	NA	NA	NA
WP_001295173.1\|4004619_4006020_-	GABA permease	NA	NA	NA	NA
WP_000772848.1\|4007549_4008998_-	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000271957.1\|4009020_4010289_-	L-2-hydroxyglutarate oxidase	NA	NA	NA	NA
WP_001315804.1\|4010308_4011286_-	carbon starvation induced protein CsiD	NA	NA	NA	NA
WP_000340076.1\|4017015_4017204_+	hypothetical protein	A0A1S6L009	Salmonella_phage	9.1e-06	69.2
WP_001120794.1\|4017358_4017478_+	hypothetical protein	NA	NA	NA	NA
WP_085950812.1\|4017982_4019196_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	2.4e-99	56.8
WP_085951104.1\|4019255_4020418_-\|transposase	IS3-like element IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.6e-50	40.2
WP_001317263.1\|4021674_4022769_+	hypothetical protein	NA	NA	NA	NA
WP_000113815.1\|4022907_4024149_-\|integrase	integrase	A0A1B5FPC6	Escherichia_phage	4.5e-101	47.3
4024353:4024399	attL	NA	NA	NA	NA
WP_024143611.1\|4024484_4025711_-	hypothetical protein	E5G6K9	Salmonella_phage	2.1e-111	49.7
WP_165746358.1\|4025714_4026737_-\|integrase	site-specific integrase	A0A1S6L016	Salmonella_phage	2.9e-186	92.9
WP_165746359.1\|4026739_4027372_-	phage repressor protein	A0A1S6KZZ7	Salmonella_phage	2.8e-59	52.4
WP_000102105.1\|4027493_4027736_+	Rha family transcriptional regulator	A0A1S6KZZ6	Salmonella_phage	6.8e-38	97.5
WP_020937144.1\|4027768_4028278_+	phage regulatory CII family protein	E5G6L3	Salmonella_phage	5.1e-83	95.9
WP_000956182.1\|4028285_4028486_+	DUF2724 domain-containing protein	E5G6L4	Salmonella_phage	7.1e-33	98.5
WP_001311552.1\|4028449_4028791_+	DUF5347 domain-containing protein	E5G6L5	Salmonella_phage	1.7e-55	98.2
WP_020937143.1\|4028857_4029091_+	DUF2732 family protein	E5G6L6	Salmonella_phage	4.1e-32	97.4
WP_000752613.1\|4029090_4029318_+	TraR/DksA family transcriptional regulator	E5G6L7	Salmonella_phage	2.7e-36	100.0
WP_165746360.1\|4029314_4030172_+	DNA adenine methylase	E5G6L8	Salmonella_phage	3.0e-160	96.8
WP_165746361.1\|4030168_4032583_+	replication endonuclease	E5G6L9	Salmonella_phage	0.0e+00	98.3
WP_001154434.1\|4032735_4032924_+	hypothetical protein	E5G6M0	Salmonella_phage	5.5e-27	98.4
WP_001217575.1\|4032934_4033168_+	DinI family protein	E5G6M1	Salmonella_phage	4.7e-36	100.0
WP_000834899.1\|4033327_4033753_-	hypothetical protein	NA	NA	NA	NA
WP_001726289.1\|4035869_4036898_-\|portal	phage portal protein	A0A1S6KZW5	Salmonella_phage	8.4e-170	88.2
WP_001726288.1\|4036897_4038664_-\|terminase	terminase ATPase subunit family protein	A0A1S6KZW3	Salmonella_phage	0.0e+00	99.5
WP_024242288.1\|4038806_4039640_+\|capsid	GPO family capsid scaffolding protein	A0A1S6KZW9	Salmonella_phage	1.1e-122	90.6
WP_000742511.1\|4039656_4040715_+\|capsid	phage major capsid protein, P2 family	E5G6M6	Salmonella_phage	2.9e-181	93.4
WP_000059191.1\|4040718_4041369_+\|terminase	terminase endonuclease subunit	E5G6M7	Salmonella_phage	8.7e-112	96.3
WP_000673523.1\|4041464_4041929_+\|head	head completion/stabilization protein	A0A1S6KZW8	Salmonella_phage	6.4e-77	89.6
WP_000868175.1\|4041928_4042132_+\|tail	tail protein X	E5G6M9	Salmonella_phage	1.4e-31	92.5
WP_000171568.1\|4042135_4042351_+	hypothetical protein	E5G6N0	Salmonella_phage	1.8e-26	80.3
WP_001069905.1\|4042331_4042844_+	lysozyme	E5G6N1	Salmonella_phage	3.1e-88	92.3
WP_000727849.1\|4042845_4043223_+	hypothetical protein	A0A1S6KZZ2	Salmonella_phage	5.1e-16	39.2
WP_001504068.1\|4043219_4043648_+\|lysis	LysB family phage lysis regulatory protein	E5G6N2	Salmonella_phage	4.9e-47	75.4
WP_165746362.1\|4043743_4044175_+\|tail	phage tail protein	E5G6N3	Salmonella_phage	2.9e-71	93.7
WP_000829127.1\|4044167_4044614_+	phage virion morphogenesis protein	A0A1S6L001	Salmonella_phage	6.6e-63	85.6
WP_001552634.1\|4044682_4045261_+\|plate	phage baseplate assembly protein V	A0A1S6KZX7	Salmonella_phage	1.1e-94	87.5
WP_053887068.1\|4045257_4045617_+\|plate	baseplate assembly protein	A0A1S6KZZ4	Salmonella_phage	3.6e-51	84.9
WP_165746363.1\|4045603_4046512_+\|plate	baseplate assembly protein	A0A1S6KZY6	Salmonella_phage	9.2e-144	90.7
WP_001086820.1\|4046504_4047110_+\|tail	phage tail protein I	A0A1S6L000	Salmonella_phage	5.2e-111	92.5
WP_165746364.1\|4047106_4048666_+\|tail	phage tail protein	M1TAS6	Escherichia_phage	3.3e-202	70.6
WP_000099202.1\|4048746_4050285_-\|transposase	IS66-like element ISEc22 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.3e-294	99.4
WP_000612626.1\|4050333_4050681_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	2.6e-62	100.0
WP_000839181.1\|4050677_4051082_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZCV4	Stx2-converting_phage	1.1e-69	99.3
WP_165746384.1\|4051163_4051730_+\|tail	tail fiber assembly protein	Q9MCR5	Enterobacteria_phage	6.6e-92	89.3
WP_115200365.1\|4051701_4052127_-\|tail	phage tail protein	A0A0F7LDZ0	Escherichia_phage	2.1e-34	61.9
WP_077775464.1\|4052123_4052525_-\|tail	phage tail protein	F1BUP1	Erwinia_phage	4.5e-10	38.4
WP_165746365.1\|4052552_4053119_+	recombinase family protein	A0A1S6L009	Salmonella_phage	3.2e-86	84.2
WP_165746366.1\|4053261_4054434_+\|tail	phage tail sheath protein	A0A1S6KZY7	Salmonella_phage	1.0e-203	90.3
WP_001207660.1\|4054443_4054959_+\|tail	phage major tail tube protein	A0A1S6L002	Salmonella_phage	2.1e-89	95.3
WP_001281009.1\|4055013_4055316_+\|tail	phage tail assembly protein	A0A1S6KZZ9	Salmonella_phage	5.3e-40	89.0
WP_000763311.1\|4055330_4055450_+\|tail	GpE family phage tail protein	E5G6Q0	Salmonella_phage	2.8e-13	87.2
WP_165746367.1\|4055442_4058520_+\|tail	phage tail tape measure protein	E5G6Q1	Salmonella_phage	0.0e+00	67.3
WP_000980394.1\|4058516_4059002_+\|tail	phage tail protein	E5G6Q2	Salmonella_phage	1.7e-67	81.2
WP_165746368.1\|4058998_4060099_+	phage late control D family protein	A0A1S6KZZ5	Salmonella_phage	1.0e-176	88.0
WP_000972389.1\|4060189_4060408_+	transcriptional activator Ogr/delta	Q53ZE7	Salmonella_virus	1.9e-18	71.9
WP_000380485.1\|4060669_4060843_+	hypothetical protein	NA	NA	NA	NA
WP_000151542.1\|4060811_4061585_+	reverse transcriptase	NA	NA	NA	NA
WP_000162574.1\|4062270_4062753_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.0e-29	46.8
4061692:4061738	attR	NA	NA	NA	NA
WP_000600190.1\|4062884_4063361_+	type II toxin-antitoxin system toxin RatA	NA	NA	NA	NA
WP_001117838.1\|4063350_4063641_+	RnfH family protein	NA	NA	NA	NA
WP_001203437.1\|4063702_4064044_-	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_000880910.1\|4064192_4065854_-	DNA repair protein RecN	NA	NA	NA	NA
WP_001059169.1\|4065939_4066818_-	NAD(+) kinase	NA	NA	NA	NA
WP_001296310.1\|4066940_4067534_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_010723175.1\|4067588_4068875_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_001189260.1\|4068895_4069762_-	inner membrane protein YpjD	NA	NA	NA	NA
WP_000460035.1\|4069853_4071215_+	signal recognition particle protein	NA	NA	NA	NA
WP_000256450.1\|4071351_4071600_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_000043335.1\|4071618_4072167_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_000264777.1\|4072197_4072965_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA

DBSCAN-SWA_4

4587823 : 4597265

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000569325.1\|4587823_4588750_+	glycine betaine ABC transporter ATP binding protein YehX	G3M9Y6	Bacillus_virus	2.8e-23	30.8
WP_000783120.1\|4588754_4589486_+	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_001216963.1\|4589466_4589574_-	protein YohO	NA	NA	NA	NA
WP_001240401.1\|4589633_4590365_-	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
WP_001295431.1\|4590586_4592272_+	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_000598641.1\|4592268_4592988_+	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295430.1\|4593034_4593505_+	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_001295429.1\|4593545_4594007_-	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	1.9e-76	100.0
WP_001317947.1\|4594131_4596132_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.1
WP_001292774.1\|4596128_4597265_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	1.1e-162	97.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP049937

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP049936

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection