CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP049989	Hydrogenophaga sp. BA0156 chromosome, complete genome	1 crisprs	csa3,DinG,DEDDh,Cas9_archaeal,cas3,WYL	1	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP049989_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP049989_1

342780-342888

Orphan

Consensus_repeat	Method
CGCAGCGGCGGAGCGTGGGGGCCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP049989_1

>merge|NZ_CP049989|1|342780-342888|CRISPRCasFinder
CGCAGCGGCGGAGCGTGGGGGCCTCACGATCCGGCGCCGGGCCGCCCCAAGCCGGATCAGCCCCCTCGGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGGGCATCA

>NZ_CP049989|1|1|342780-342888|CRISPRCasFinder
CGCAGCGGCGGAGCGTGGGGGCCTCA	CGATCCGGCGCCGGGCCGCCCCAAGCCGGATCAGCCCCCTCGGGGGGCAGCGACCCG
CGCAGCGGCGGAGCGTGGGGGCATCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP049989.1\|WP_166223550.1\|336656_337718_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP049989.1\|WP_166223582.1\|349924_350977_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381320
NZ_CP049989.1\|WP_166223565.1\|343443_344361_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|366166
NZ_CP049989.1\|WP_166223547.1\|335325_336342_-\|porin	unknown	unknown	gnl\|CDD\|238208
NZ_CP049989.1\|WP_166223533.1\|331196_331652_+\|thiosulfate-oxidation-carrier-protein-SoxY	unknown	unknown	gnl\|CDD\|275281
NZ_CP049989.1\|WP_166223559.1\|341628_342733_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP049989.1\|WP_166223570.1\|346125_346836_-\|IclR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224332
NZ_CP049989.1\|WP_166223585.1\|350973_351468_+\|aminoacyl-tRNA-deacylase	unknown	unknown	gnl\|CDD\|237976
NZ_CP049989.1\|WP_166223536.1\|331696_332008_+\|thiosulfate-oxidation-carrier-complex-protein-SoxZ	unknown	unknown	gnl\|CDD\|370108
NZ_CP049989.1\|WP_166223567.1\|344395_346129_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341275
NZ_CP049989.1\|WP_166223576.1\|347881_349120_+\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NZ_CP049989.1\|WP_166223553.1\|337925_338936_-\|class-1-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236458
NZ_CP049989.1\|WP_166223579.1\|349083_349767_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|225439
NZ_CP049989.1\|WP_166223539.1\|332051_332858_+\|sulfur-oxidation-c-type-cytochrome-SoxA	unknown	unknown	gnl\|CDD\|275277
NZ_CP049989.1\|WP_166223573.1\|346931_347885_+\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|163676
NZ_CP049989.1\|WP_166223544.1\|333515_335240_+\|thiosulfohydrolase-SoxB	unknown	unknown	gnl\|CDD\|275279
NZ_CP049989.1\|WP_166223588.1\|351501_352131_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl\|CDD\|234691
NZ_CP049989.1\|WP_166223542.1\|332871_333519_+\|sulfur-oxidation-c-type-cytochrome-SoxX	unknown	unknown	gnl\|CDD\|275278
NZ_CP049989.1\|WP_166223591.1\|352127_352484_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100007
NZ_CP049989.1\|WP_166223556.1\|338953_341626_-\|aminopeptidase-N	unknown	unknown	gnl\|CDD\|237585

Protein	Function_ID	Function_description	E-value
NZ_CP049989.1\|WP_166223582.1\|349924_350977_+\|aldo/keto-reductase	gnl\|CDD\|381320	cd19094, AKR_Tas-like, Escherichia coli Tas protein and similar proteins. Escherichia coli Tas protein is the prototype of this family. It is an NADP(H)-dependent aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NADP(H) as a hydride donor.	1.85402e-175
NZ_CP049989.1\|WP_166223565.1\|343443_344361_-\|alpha/beta-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.61375e-27
NZ_CP049989.1\|WP_166223547.1\|335325_336342_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	8.89491e-54
NZ_CP049989.1\|WP_166223533.1\|331196_331652_+\|thiosulfate-oxidation-carrier-protein-SoxY	gnl\|CDD\|275281	TIGR04488, sulfur_oxidation_protein_SoxY, thiosulfate oxidation carrier protein SoxY. Members of this family are bona fide SoxY, the sulfate carrier protein with the GGCGG ir GGCG swinging arm C-terminal sequence. The Cys in the swinging arm is the residue to which the inorganic sulfate moiety becomes covalently attached. In some species, a closely related paralog occurs as well (TIGR04487), with a swinging arm sequence AACIE. More distantly related forms have an additional C-terminal SoxZ-related domain. All members are periplasmic and have an N-terminal twin-arginine translocation (TAT) signal sequence.	1.17003e-53
NZ_CP049989.1\|WP_166223559.1\|341628_342733_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP049989.1\|WP_166223570.1\|346125_346836_-\|IclR-family-transcriptional-regulator	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	4.58656e-37
NZ_CP049989.1\|WP_166223585.1\|350973_351468_+\|aminoacyl-tRNA-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	3.72337e-53
NZ_CP049989.1\|WP_166223536.1\|331696_332008_+\|thiosulfate-oxidation-carrier-complex-protein-SoxZ	gnl\|CDD\|370108	pfam08770, SoxZ, Sulphur oxidation protein SoxZ. SoxZ forms an anti parallel beta structure and forms a complex with SoxY. Sulphur oxidation occurs at the thiol of a conserved cysteine residue of the SoxY subunit.	9.79676e-41
NZ_CP049989.1\|WP_166223567.1\|344395_346129_+\|AMP-binding-protein	gnl\|CDD\|341275	cd05971, MACS_like_3, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	0
NZ_CP049989.1\|WP_166223576.1\|347881_349120_+\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	3.80709e-138
NZ_CP049989.1\|WP_166223553.1\|337925_338936_-\|class-1-fructose-bisphosphatase	gnl\|CDD\|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	0
NZ_CP049989.1\|WP_166223579.1\|349083_349767_-\|OmpA-family-protein	gnl\|CDD\|225439	COG2885, OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane].	1.11528e-38
NZ_CP049989.1\|WP_166223539.1\|332051_332858_+\|sulfur-oxidation-c-type-cytochrome-SoxA	gnl\|CDD\|275277	TIGR04484, sulfur_oxidation_protein_SoxA, sulfur oxidation c-type cytochrome SoxA. Members of this family are SoxA, a c-type cytochrome with a CxxCH motif, part of a heterodimer with SoxX. SoxXA, SoxYZ, and SoxB contribute to thiosulfate oxidation to sulfate.	3.39196e-92
NZ_CP049989.1\|WP_166223573.1\|346931_347885_+\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	3.02914e-144
NZ_CP049989.1\|WP_166223544.1\|333515_335240_+\|thiosulfohydrolase-SoxB	gnl\|CDD\|275279	TIGR04486, Sulfur_oxidation_protein_SoxB, thiosulfohydrolase SoxB. SoxB, a di-manganese(II) enzyme, works with SoxYZ and the c-type cytochrome SoxXA in oxidation of thiosulfate to sulfate.	0
NZ_CP049989.1\|WP_166223588.1\|351501_352131_+\|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl\|CDD\|234691	PRK00220, PRK00220, glycerol-3-phosphate 1-O-acyltransferase PlsY.	1.17887e-79
NZ_CP049989.1\|WP_166223542.1\|332871_333519_+\|sulfur-oxidation-c-type-cytochrome-SoxX	gnl\|CDD\|275278	TIGR04485, monoheme_cytochrome_c_SoxX, sulfur oxidation c-type cytochrome SoxX. Members of this family are SoxX, a c-type cytochrome with a CxxCH motif, part of a heterodimer with SoxA. SoxXA, SoxYZ, and SoxB contribute to thiosulfate oxidation to sulfate.	3.81772e-33
NZ_CP049989.1\|WP_166223591.1\|352127_352484_+\|RidA-family-protein	gnl\|CDD\|100007	cd06150, YjgF_YER057c_UK114_like_2, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	5.16872e-50
NZ_CP049989.1\|WP_166223556.1\|338953_341626_-\|aminopeptidase-N	gnl\|CDD\|237585	PRK14015, pepN, aminopeptidase N; Provisional.	0

>NZ_CP049989.1|WP_166223559.1|341628_342733_-|peptide-chain-release-factor-2
MDAEQINAIQSQLKDLSTRVVELRRYLDYDAKASKLKEVESALEDPTVWDNPKRAQDLSKERKSLEDVVLVLDRLGSELADNSELFEMSAADNDEAGLRTIADEAAKVQAEVERLEFRRMFNNPADPLNCFVDIQAGAGGTEACDWASMLLRQYLRYAERKGFTTTVEDETPGDTAGIKSATIKVEGEYAFGLLRTETGVHRLVRKSPFDSSGGRHTSFASIFVYPEVDDTIEIEINPADVRVDTYRASGAGGQHINKTDSAVRLTHIPTGIVVQCQDGRSQHSNRDVAWKRLRSRLYDHEMRKRMEEQQKLEDTKTDVGWGHQIRSYVLDNSRIKDLRTNVEISATQKVLDGDLDAFIEASLKQGV
>NZ_CP049989.1|WP_166223556.1|338953_341626_-|aminopeptidase-N
MSSLREGPTTVVRREDYAPPAYWIDTVELTFDLDPAKTRVLNRMTLRRNAAVAAQPLRLDGEELNLARVLVNGAGCSFKMDAGQLVLDNLPEGNEPFTLEIFTTCAPEKNSQLMGLYVSQGTFFTQCEAEGFRRITYFLDRPDVMASYTVTLRADKARYPVLLSNGNLEEEGPLPDGRHFAKWVDPHRKPSYLFALVAGNLVAREQRIVSRSGKEHLLQVFVRRGDMDKTEHAMQSLIASVAWDEARFGLPLDLERFMIVATSDFNMGAMENKGLNIFNTKYVLANSATATDTDFANIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSMDLCAEPSARAVKRIEDVRVLRTAQFPEDAGPMAHPVRPDSYVEINNFYTVTVYEKGAEVVRMMQTLVGREGFARGMKLYFERHDGQAVTCDDFAQAIADANPDSALARQLEVFKRWYSQAGTPRVRAEGRYDAEARRYTLTLSQHCAPTPGQAVKQPFLIPVALGLLDAQGRELPLPESQRLVVLADASATVVFDDIDSEPVPSLLRGFSAPVVLEYADSDAQLLTLLAHDSDPFNRWEAGQRLALRRALAAVRADGPVAQPLDAAFIDAMRAVLRHDTLDAAFKELTLTLPSETYISEQLEVVDPQRVHAVREAMREQLAQALHADWAWAYEQHRDNGAYRPDPLSAGRRALAGMALTMLCLDARQSGDAVWPGKAYQRFKDAGNMTDRFNALSALVVSGHALAREALPRFHAMFRDEALVLDKWFALQAGAPDRGGNILPAVRQLMAHPDFQLRNPNRARSVIFSYCNANPGAFHRADAAGYVFWSDRVLEIDRFNPQVAARLARALDRWKKLAEPYRSAAREAIARVAAQAELSNDVREVVTRALSED
>NZ_CP049989.1|WP_166223553.1|337925_338936_-|class-1-fructose-bisphosphatase
MSQRISLTRYLVEKQRVDGHIPSQLRLLIEVVARSCKSISHAVNKGALGGVLGSADSENVQGEVQKKLDIIANEVLIEANEWGGHLAAMASEEMDSIYLVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKPEGSGAGVSEADFLQPGSKQVAAGYCVYGPQTTLVLTVGDGVAMFTLDREQGSFVLTQEDVKIPADTKEFAINMSNMRHWDTPVKRYIDECLQGKEGPRGKDFNMRWIASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAWLVEQAGGAATNGRERILDVNPTKLHERVSVILGSKNEVDRITAYHREG
>NZ_CP049989.1|WP_166223550.1|336656_337718_+|hypothetical-protein
MQKFVKFALGGVAMSGLWGCATPASEANLGNPAPLAQSVLDGKVRPNEYLSIGQQATTLPLCVLIVYDTPMAVAATDWLLGNGADVNLDCRNDPSSGKPLNMVARAMGYAMAERNSPKVAFLQGRADQLIQRGGKTAEGESSRQSVLAIAEHWGKVSSEQKAYSEQWLREERQKNAQMLKDLGAVAVGVTGAYIAARQAGSLESPSAARSAGASAGPAMTGNPATVAAAKTQPSTSSSDPASRPSADQSTPARKTYPFQDTKAYASEGIGHESRQQALQSLHEQRQQLEGVFMGHAPEWRVVRQEEPVCTQHGSRLGSSSKDHWRCTMKVTYAGQSWLDQNNAGRSNGTGATR
>NZ_CP049989.1|WP_166223547.1|335325_336342_-|porin
MKKSLIALAALATLSGAALAQSSVTIYGRLDASVGSNKAGAPGVAKSVSQLESGLLSTSRLGFRGTEDLGGGMKAIFQLEGELKVDDGTAAGFSFNRMSIVGLQAGFGTIKLGRHDTSFDDIRDISVSSNLWDSEFSPTKVAYVNSVGGVAVAHVADYSSRASNQIRYESPSFGGFTAGVSYGFDEQAAPVKRDVTALNVRYRAGGLDAGIGYQEQDNEVAASKREYTTIAGAYNFGMFRVSGGYNKAEQGTLESTGYTIGANMPVDAWDFSVGYATNKSELAGVTSAKSSGFSAGATYSLSKRTRVYAAFLNGKAENAAGTKIADRKLYAVGVRHDF
>NZ_CP049989.1|WP_166223544.1|333515_335240_+|thiosulfohydrolase-SoxB
MSLGRRDFLQMLAAASAAGMALEHRDALAAAPAAAERFYDVPRYGNVSFLHFTDCHAQLTPVHFREPSVNLGVAEAVGKAPHLVGEALLKHFNIRPGTREAHAFSYLDFAQAARTYGKVGGFAHLATLVKQLRAQRPHAWLLDGGDTWQGSATALWTNAQDMVDACKKLGVDIMTPHWEFTFGARRVQEIVEKDFKGRIEFLAHNVKTTDFEDLVFKPYTLRDMNGVPVAVIGQAFPYTPIANPRYMVPDWTFGIQEDHLQKMVDEVRGKGAQVVVLLSHNGMDVDLKLASRVRGIDAILGGHTHDGMPQPTVVKNAGGQTLVTNAGSNTKFLGVLDFDVRGGQVQGYRYKLLPIFANLLKADVDMQAHIDAVRAPYKDKLGEKLAVTQDTLYRRGNFNGSWDQLICDALIEVKGADLSFSPGVRWGTSLLPGDTITMEHLMDQTAITYPSTTLNTFTGAQIKEILEDVADNIFNPDPYYQQGGDMVRVGGMQYTIAPNERMGSRIQNMTLKGRPVEADKTYKVAGWASVQEGVKGEPVWDVVATHLRSRKVIKGVKVNAPRIVGMAGNPGIAA
>NZ_CP049989.1|WP_166223542.1|332871_333519_+|sulfur-oxidation-c-type-cytochrome-SoxX
MKRHHTLAALALPVLLAACSMGPSPADIDKATADILKSSFQARGIATLDRLDQDQANAACVQADISGKPLDEKLAKAVEEANMKTIRWPSDGKFLGDWKQGEAIAQSGRGLTWTDAANQPNGGNCYNCHQISKEEISFGTLGPSLYNYGKLRGVTDPASAASKPIVEYTWGKLYNARAYNACSQMPRAGHKGILTEQQLKHVMALLLDPNSPVNK
>NZ_CP049989.1|WP_166223539.1|332051_332858_+|sulfur-oxidation-c-type-cytochrome-SoxA
MKHPVLRVALLAAGVLAAGAAQAQASTAEGIAKYREMLQDGNPAELFEMKGEELWKQKRGPKNVSLEQCDLGKGPGVIKGAFVELPRFFKDTNRIEDLEGRLITCMETLQGFKGEDIRKTAFGRGEMANVTALATYVATASKGMKFNLPQSHLQEKLMYETGKRLFFTRGGTHDFSCASCHGSDDKRIRLQDLPNLTKNPGDGIGFAAWPAYRVSNSQMWGMQLRLNDCFRQMRWPEPKFGSDATLALSTYMGVNAKGAESIVPAIKR
>NZ_CP049989.1|WP_166223536.1|331696_332008_+|thiosulfate-oxidation-carrier-complex-protein-SoxZ
MADPMRIRAAVADGETTVRVLMSHVMEPGTRRDAAGNLIPGHFITNVDATHNGKTVLSAQFTGAVAQNPFLSFKFKGGAKGDKVVVKWSDNKGDSRTDEATIA
>NZ_CP049989.1|WP_166223533.1|331196_331652_+|thiosulfate-oxidation-carrier-protein-SoxY
MNHTRRDALKTTGALATLVSMGIVTQSQAHAALERSAFEGKSLADALKAVGGTPANSDQVSVVAPDIAENGAVVPIGAASKLPNTTEIFLIVEKNPMPLAAAFTIPAGTAPEVSTRLKMGQSSNVIAVVKADGKLYSATKETKVTLGGCGG
>NZ_CP049989.1|WP_166223565.1|343443_344361_-|alpha/beta-hydrolase
MYQVQRPSRSDFLPIRGWRYHVRSWGEPDPSRPPLVLVHGWMDVAASWQFVVDALREQRHIVAPDWRGYGDTTFDGPAPDSYWFPDYLGDLDALLDTLFGDRAVDLVGHSMGGHVATLYAGARPQRIRRLVNLEGFGMPASVPAQAPTRYAHWLDEIRAQRRGDMDLSDYADADGVARRLMKTNPRLAPDKADWLARQWARPNSEGRWAILGDSAHKVSNAVLFRPDEAIAVYQRIGAPTLVVTAGDDSLGQWWKGRYTLAEFLQRIGHVPNLRHEVVPDAGHMMHHDQPALLAALIEAFLSDKT
>NZ_CP049989.1|WP_166223567.1|344395_346129_+|AMP-binding-protein
MRRRQDRDTAPAAAPDLYASLHAGFRWRVPEAFNMAEVCMRRWANDPDTARQTAVIATAPDQPDRRHSYAELFAQANRLANALQVLGVQRGDRVAIVLPQRFETAVAYMAVLQLGAVAMPLSQLFGPEALQFRLHDSEAVLAVCDASTLAAVQSVSAHCPRLQDVIAVDAAGGSALDWTALLAQQPEGFEPAHTRADEAAVLIYTSGTTGNPKGALIPHRALIGNLTGFVCSQNWFGFDPFDAAKPSQAVFWSPADWAWTGGLMDALLPTLYFGRPIVAHNGRFSAQTAFELIERHGVTHSFLFPTALKAMMKAFPQPRRHFRLALQGLMSAGEAVGDAVYHWCRDGLGVPVNEMFGQTEINYVVGNCTRLWPAKPGSMGKGYPGHRVAVIDEEGRECPVGVPGDVAVHRLDVHGEPDPIFFLGYWKNEAATRGKYTGDPADSWCRTGDLAVRDADGYLWYQGRADDVFKAAGYRIGPSEIENCLVKHPAVANAAVVPKPDAERGAVVKAYVVLSPGRAGDAALIAELQAHVKGRLAPYEYPKEIEFIDALPMTTTGKVQRRVLRLQEEARAKAAAR
>NZ_CP049989.1|WP_166223570.1|346125_346836_-|IclR-family-transcriptional-regulator
MPRKSSHASVADDNAAPGGAAAVDRAISLLAAFRPGDRSLGVSELAERTRLYNSTVLRLLASLAHGGLVQRTPGGRWALGPEIARLAALHAEAFSLEDLVLPEMRALGARTQESVAFHVRQGDQRLVLFRVDSPHLLRDHVRAGDLLPLNRGAGGRVLMAFAGARGKLHEQVRRDGYVALTGDRVAGLVGISAPVWRTGHELVGALTLTVPEPRAKPAFVDALRASAARLTKVLGG
>NZ_CP049989.1|WP_166223573.1|346931_347885_+|hydroxymethylglutaryl-CoA-lyase
MTTDVLISEVGPRDGLQSVKATMPTAHKLAWIDGLHAAGLREIEVGSFVPARLLPQMADVAEVVRHALTRPGLTVMALVPNVRGAEAALASGVHKLTLPVSASEAHSLANVRKTRAQMVDEVRAVVALRRASAPKVRVEAGLSTAFGCTLQGPVPEDDVVRLAVALAEAGADEIGLSDTTGMANPAQVRRLFRRVRAEIGERTGAAHLHNTRGLGLANCLAAHDAGVRTFDSSQGGLGGCPYAPGASGNVVTEDLVFMFEAMGVRTGVDLDRLMAAREALRAGLPGEPLYGMTPEAGLTRGFTYADGRVPAAMKGTA
>NZ_CP049989.1|WP_166223576.1|347881_349120_+|CoA-transferase
MNPSHELPLSGLRVVELTHMVMGPTCGLILADLGAEVIKVEPLGGDSTRRLLGSGAGFFGTFNRNKKSLAVDVKDPRGREIVLRLLARADVFSENFKSGAMDQLGLGHEALTRLNPRLISVSHKGFLPGPYEHRTALDEVVQMMGGLAYMTGPEGRPLRAGTSVNDIMGGMFGAIGVLAALAQREKTGRGQRVQSALFENNVFLMAQHMMQFAVTGRPAAPMPGRISAWAVYDVFTVKDGEQVFLAAVSDSQWALMCEAFGFDDLRDDPRLVGNNARVQARDWMLPLLRERFAGFSAAELGARFERIGLPYAPITKPQDLFDDPHLLASGGLAEVCLPPDTSCAGRPVQTRTALLPITLDGARPGVRSAPPALGEHSEAVLTELGYTPAEIAQLRDAGVLAQRCAAVAGSAT
>NZ_CP049989.1|WP_166223579.1|349083_349767_-|OmpA-family-protein
MNTSPSSFTRGLTLLTVAAAIAVTGCANMSETQRDSAKGAGIGAAAGVVLGGLTGGSKGAAQGAVLGAGAGALGGYIWSTRMQEQKKQMEAATAGTGIGVSQTADNRLKLDVPADAGFASGRSTLSPTLVRVLGQFATTLQQNQATQVSIIGHTDSSGSDAINNPLSFDRANATRDYLVGRGVSAARISTDGRGSREPVADNGTPQGRALNRRVEIYVAEPATAAQR
>NZ_CP049989.1|WP_166223582.1|349924_350977_+|aldo/keto-reductase
MKHLPLGQSPLHVSPICLGTMTFGEQVDQPTAHAILDRSLERGVNFIDAAEMYSVPARAETCGATETIIGHWFARTPGLRQKVVLATKVAGPSRGMPWIRGEVSGLSKAEIVNACEGSLRRLQTDVIDLYQIHWPARNVPAFGALYFDPSKDKPHASIHEQLDAMADLVKAGKVRAIGLSNETPYGVHEFVRLAEQHGLPRVATVQNPYCLINRSYENGLDESCHRLGVSLLAYSPLGFGLLTGKYDDTGLVGDHGRMALYDSMRKQRWGRPEALATARRYNALAREHGLTPAQLALAFCYRNWRVASTIIGVTSVAQLDQCLDAWDVALTPELLTAIDQIRWESRDPAQ
>NZ_CP049989.1|WP_166223585.1|350973_351468_+|aminoacyl-tRNA-deacylase
MSKKAAHVSETPATAWLKAHGVAYTEHPYEYLEHGGAQHSAQVLGLDPFAVVKTLIMQDEAARPLAVLMHGNRTVSTKNLARQIGAKSVEPCKPEVANRHSGFLVGGTSPFGLKRAMPVWVESTVLELPKIWINGGRRGFLVGIDPAVLTAPLGAKPVQCALAE
>NZ_CP049989.1|WP_166223588.1|351501_352131_+|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MQAFYPALATLAAYLIGSLSFAVLVSRLMGLSDPRTYGSKNPGATNVLRSGNKAAAVITLLLDAFKGWLPVVLVQAYGERFGLGAGTVALVGFAAFLGHLFPVFFRFQGGKGVATAAGVILAFNPWLGLASLATWLIIAVFFRYSSLASIVTAVFAPAYYLLGADVAWDAPGAMVLGLAAMAVLLVWRHAENINRLIAGTESKLGSKKK
>NZ_CP049989.1|WP_166223591.1|352127_352484_+|RidA-family-protein
MSQDITRVGMAARYSEAAVFNGIVFLAGMVPERGDVDIRGQTEDVLQQVEQRLRECGSDKSRILRTEIFLTDIRDIAAMNEVWDAWVVPGAAPPRATVQAALANPAYRIEIVVTAAQA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	535601-535657	0	1.0
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	2049874-2049930	0	1.0
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	3847497-3847553	0	1.0
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	1977918-1977974	2	0.965
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	2334488-2334544	2	0.965
NZ_CP049989_1	1.1\|342806\|57\|NZ_CP049989\|CRISPRCasFinder	342806-342862	57	NZ_CP049989.1	2668440-2668496	2	0.965

1. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 535601-535657, mismatch: 0, identity: 1.0

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	Protospacer
*********************************************************

2. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 2049874-2049930, mismatch: 0, identity: 1.0

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	Protospacer
*********************************************************

3. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 3847497-3847553, mismatch: 0, identity: 1.0

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	Protospacer
*********************************************************

4. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 1977918-1977974, mismatch: 2, identity: 0.965

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgatccgccgccgggccgccccaaggcggatcagccccctcggggggcagcgacccg	Protospacer
******* ***************** *******************************

5. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 2334488-2334544, mismatch: 2, identity: 0.965

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgatccgccgccgggccgccccaaggcggatcagccccctcggggggcagcgacccg	Protospacer
******* ***************** *******************************

6. spacer 1.1|342806|57|NZ_CP049989|CRISPRCasFinder matches to position: 2668440-2668496, mismatch: 2, identity: 0.965

cgatccggcgccgggccgccccaagccggatcagccccctcggggggcagcgacccg	CRISPR spacer
cgacccggcgccgggccgccccaagccgggtcagccccctcggggggcagcgacccg	Protospacer
***.*************************.***************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1117329 : 1126430

Rhodoferax_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166225666.1\|1117329_1118955_+	hypothetical protein	A0A0E3JSB2	Rhodoferax_phage	1.3e-55	36.3
WP_166225669.1\|1118951_1119206_+	hypothetical protein	NA	NA	NA	NA
WP_166225671.1\|1119202_1119523_+	cupin domain-containing protein	A0A1X9IAE2	Xanthomonas_phage	2.0e-29	65.3
WP_166225674.1\|1119524_1120490_+	hypothetical protein	A0A0E3GMA9	Rhodoferax_phage	4.2e-22	43.8
WP_166225677.1\|1120492_1121803_+	hypothetical protein	NA	NA	NA	NA
WP_166225680.1\|1121802_1123653_+	hypothetical protein	A0A0E3M2A5	Rhodoferax_phage	7.0e-106	42.1
WP_166225683.1\|1123836_1125297_+	hypothetical protein	A0A1B1IRA2	uncultured_Mediterranean_phage	2.7e-12	38.5
WP_166225686.1\|1125311_1125632_+	hypothetical protein	NA	NA	NA	NA
WP_166225689.1\|1125633_1125933_+	hypothetical protein	NA	NA	NA	NA
WP_166225692.1\|1125929_1126430_+	hypothetical protein	X5KCC3	Pseudomonas_phage	9.8e-39	51.8

DBSCAN-SWA_2

3307934 : 3361547

uncultured_Caudovirales_phage(45.45%)

integrase,transposase

attL 3302120:3302135|attR 3366503:3366518

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3302120:3302135	attL	NA	NA	NA	NA
WP_006217728.1\|3307934_3308330_+\|transposase	transposase	NA	NA	NA	NA
WP_003121550.1\|3308326_3308659_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_166228553.1\|3308735_3310286_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	6.0e-119	46.4
WP_010791743.1\|3310308_3310728_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_077446928.1\|3310783_3311884_+	cation transporter	NA	NA	NA	NA
WP_166228555.1\|3312092_3312830_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	2.0e-88	68.4
WP_166231371.1\|3312849_3314034_-	MFS transporter	NA	NA	NA	NA
WP_166228557.1\|3314059_3315526_-	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_166231374.1\|3315602_3315929_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_166228559.1\|3316025_3316451_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	5.0e-44	62.1
WP_166231377.1\|3316447_3317485_-	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_166228561.1\|3317484_3318003_-	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	4.0e-27	43.2
WP_166228563.1\|3318013_3318346_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_166228565.1\|3318356_3319625_-	organoarsenical effux MFS transporter ArsJ	NA	NA	NA	NA
WP_166228567.1\|3319638_3320697_-	ArsJ-associated glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_166231380.1\|3321174_3321672_+	c-type cytochrome	NA	NA	NA	NA
WP_166228569.1\|3321680_3322307_+	hypothetical protein	NA	NA	NA	NA
WP_166231383.1\|3322294_3323374_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4J2Q2	uncultured_Caudovirales_phage	7.7e-89	56.7
WP_166228571.1\|3324306_3327423_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_083293337.1\|3327419_3328964_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_166228573.1\|3329085_3330414_-	TolC family protein	NA	NA	NA	NA
WP_166228575.1\|3330502_3330898_-	hypothetical protein	NA	NA	NA	NA
WP_070400929.1\|3331439_3331724_+	CopK family periplasmic copper-binding protein	NA	NA	NA	NA
WP_166228577.1\|3331744_3333103_-	heavy metal sensor histidine kinase	NA	NA	NA	NA
WP_070400928.1\|3333115_3333796_-	heavy metal response regulator transcription factor	W8CYM9	Bacillus_phage	3.8e-33	36.7
WP_070400927.1\|3333962_3335036_+	TolC family protein	NA	NA	NA	NA
WP_070400926.1\|3335057_3336437_+	copper oxidase	NA	NA	NA	NA
WP_070400925.1\|3336489_3336978_+	cupredoxin family protein	NA	NA	NA	NA
WP_070400924.1\|3337014_3337350_+	copper-binding protein	NA	NA	NA	NA
WP_070400923.1\|3338057_3340355_-	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.4e-79	32.8
WP_070400922.1\|3340500_3340740_-	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_139147135.1\|3340877_3341111_-	hypothetical protein	NA	NA	NA	NA
WP_070400920.1\|3341146_3341554_-	DUF302 domain-containing protein	NA	NA	NA	NA
WP_166228579.1\|3341564_3342083_-	hypothetical protein	NA	NA	NA	NA
WP_166228581.1\|3342270_3342711_-	hypothetical protein	NA	NA	NA	NA
WP_166228584.1\|3342860_3344492_-	AAA family ATPase	NA	NA	NA	NA
WP_166228586.1\|3344509_3346588_-	hypothetical protein	NA	NA	NA	NA
WP_166228588.1\|3346803_3348345_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	7.8e-18	29.0
WP_166228590.1\|3348337_3348598_-	hypothetical protein	NA	NA	NA	NA
WP_166228592.1\|3348749_3348968_+	helix-turn-helix transcriptional regulator	D7RWM4	Brochothrix_phage	3.9e-08	44.3
WP_166228594.1\|3349297_3349720_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_166228596.1\|3349800_3350457_+	cation transporter	NA	NA	NA	NA
WP_166228598.1\|3350440_3350812_+	DUF3703 domain-containing protein	NA	NA	NA	NA
WP_166228600.1\|3350838_3351213_+	hypothetical protein	NA	NA	NA	NA
WP_166228602.1\|3351829_3352246_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_166228604.1\|3352242_3352899_+	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_166228606.1\|3352895_3353528_+	SCO family protein	NA	NA	NA	NA
WP_166228607.1\|3354096_3354720_+\|integrase	tyrosine-type recombinase/integrase	A0A0A8WF93	Clostridium_phage	8.8e-13	35.0
WP_166228609.1\|3355099_3356617_+	recombinase family protein	NA	NA	NA	NA
WP_166231386.1\|3356673_3356919_-	hypothetical protein	NA	NA	NA	NA
WP_166228611.1\|3357192_3357636_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_166228613.1\|3357924_3358914_-	hypothetical protein	NA	NA	NA	NA
WP_143434174.1\|3359176_3359593_+\|transposase	transposase	NA	NA	NA	NA
WP_166228615.1\|3359589_3359922_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_166228617.1\|3360002_3361547_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.1e-108	50.4
3366503:3366518	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3879586 : 3888962

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166229528.1\|3879586_3880693_-	DegT/DnrJ/EryC1/StrS family aminotransferase	A0A2K9L0G1	Tupanvirus	1.7e-35	29.5
WP_166229530.1\|3880715_3881840_-	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	4.2e-13	24.3
WP_166229532.1\|3881845_3882319_-	N-acetyltransferase	NA	NA	NA	NA
WP_166229534.1\|3882315_3883374_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_166229536.1\|3883418_3884549_-	GDP-mannose 4,6-dehydratase	M1HVG7	Acanthocystis_turfacea_Chlorella_virus	1.8e-133	63.3
WP_166229538.1\|3884541_3885531_-	GDP-L-fucose synthase	A0A1J0F9I6	Only_Syngen_Nebraska_virus	1.3e-90	52.4
WP_166229540.1\|3885527_3886106_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	7.1e-49	54.1
WP_166229542.1\|3886102_3887008_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.2e-97	58.9
WP_166229544.1\|3887004_3887901_-	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	1.0e-22	34.6
WP_166229546.1\|3887897_3888962_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.6e-86	48.2

DBSCAN-SWA_4

4339812 : 4349316

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166223077.1\|4339812_4340781_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.3e-18	28.8
WP_166230336.1\|4340777_4341803_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	8.8e-18	31.0
WP_166230338.1\|4341807_4342656_-	SIS domain-containing protein	NA	NA	NA	NA
WP_166230340.1\|4342720_4343662_+	transaldolase	A0A1D8KSY7	Synechococcus_phage	1.9e-11	35.7
WP_166230342.1\|4343748_4345395_-	chaperonin GroEL	A0A219YK78	uncultured_virus	9.4e-171	60.8
WP_166230344.1\|4345431_4345722_-	co-chaperone GroES	A0A221S4A8	uncultured_virus	8.0e-17	43.6
WP_166230346.1\|4345939_4347964_-	PAS domain S-box protein	NA	NA	NA	NA
WP_166230348.1\|4348131_4349316_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.6e-117	58.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage