CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_AP021888	Thiomicrorhabdus sp. AkT22	3 crisprs	csa3,PD-DExK,DEDDh,cas3,DinG,csx1	0	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP021888_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP021888_1

265031-265291

Orphan

Consensus_repeat	Method
ATGGGGCGCAGGCTTTAGCCTGCTGAG	PILER-CR

3 spacers

The CRISPR arrays of NZ_AP021888_1

>merge|NZ_AP021888|1|265031-265291|PILER-CR
ATGGGGCGCAGGCTTTAGCCTGCTGAGTGAGGATGGATTGCAGAATAGAAGGCTAAAGCCTTCGCCCCAAAAGTTGACGGGAGTTAATGGGGCAGGCCTAAGCATGCTGAGAGTTTATGCGTTATTTAACAGAATGCAGACGGGAGTTATGGGGCGCAGGCTTCAGCCTGCTTAATGTTGATAGTTTATTTAACAGAAGGCTAAAGCCTTCGCCCCGAAGGCAGACGAGAGTAAATGGGGCGCAGGCTTTAGCCTGCTGGG

>NZ_AP021888|1|1|265031-265291|PILER-CR
ATGGGGCGCAGGCTTTAGCCTGCTGAG	TGAGGATGGATTGCAGAATAGAAGGCTAAAGCCTTCGCCCCAAAAGTTGACGGGAGTTAAT
GGGGCAGGCCTAAGCATGCTGAGAGTT	TATGCGTTATTTAACAGAATGCAGACGGGAGTTATGG
GGCGCAGGCTTCAGCCTGCTTAATGTT	GATAGTTTATTTAACAGAAGGCTAAAGCCTTCGCCCCGAAGGCAGACGAGAGTAAATGGGGC
GCAGGCTTTAGCCTGCTGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP021888.1\|WP_173289892.1\|267072_268269_-\|8-amino-7-oxononanoate-synthase	unknown	unknown	gnl\|CDD\|235655
NZ_AP021888.1\|WP_173292339.1\|266244_267033_-\|pimeloyl-ACP-methyl-ester-esterase-BioH	unknown	unknown	gnl\|CDD\|273783
NZ_AP021888.1\|WP_173292338.1\|256006_258271_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_AP021888.1\|WP_173289898.1\|270169_270664_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|310737
NZ_AP021888.1\|WP_173289894.1\|268283_269312_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
NZ_AP021888.1\|WP_173289886.1\|259775_261752_+\|TIGR03545-family-protein	unknown	unknown	gnl\|CDD\|274640
NZ_AP021888.1\|WP_173289876.1\|255162_255717_-\|TRAP-transporter-small-permease-subunit	unknown	unknown	gnl\|CDD\|227011
NZ_AP021888.1\|WP_173289878.1\|255713_255908_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173289888.1\|261788_265013_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|185001
NZ_AP021888.1\|WP_173289902.1\|272563_273847_+\|outer-membrane-protein-transport-protein	unknown	unknown	gnl\|CDD\|224978
NZ_AP021888.1\|WP_173289900.1\|270673_272545_+\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320692
NZ_AP021888.1\|WP_173289874.1\|253766_255143_-\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|227010
NZ_AP021888.1\|WP_173292337.1\|249309_251328_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_AP021888.1\|WP_173289904.1\|273858_278913_+\|tandem-95-repeat-protein	unknown	unknown	gnl\|CDD\|380078
NZ_AP021888.1\|WP_173289883.1\|259272_259764_+\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|200289
NZ_AP021888.1\|WP_173289907.1\|278947_280765_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227334
NZ_AP021888.1\|WP_173289896.1\|269389_270076_+\|ComF-family-protein	unknown	unknown	gnl\|CDD\|223970
NZ_AP021888.1\|WP_173289881.1\|258340_259192_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173289872.1\|251570_253700_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227334
NZ_AP021888.1\|WP_173289890.1\|265312_266239_-\|malonyl-ACP-O-methyltransferase-BioC	unknown	unknown	gnl\|CDD\|273953

Protein	Function_ID	Function_description	E-value
NZ_AP021888.1\|WP_173289892.1\|267072_268269_-\|8-amino-7-oxononanoate-synthase	gnl\|CDD\|235655	PRK05958, PRK05958, 8-amino-7-oxononanoate synthase; Reviewed.	0
NZ_AP021888.1\|WP_173292339.1\|266244_267033_-\|pimeloyl-ACP-methyl-ester-esterase-BioH	gnl\|CDD\|273783	TIGR01738, Pimeloyl-_methyl_ester_esterase, pimelyl-[acyl-carrier protein] methyl ester esterase. This CoA-binding enzyme is required for the production of pimeloyl-coenzyme A, the substrate of the BioF protein early in the biosynthesis of biotin. Its exact function is unknown, but is proposed in ref 2. This enzyme belongs to the alpha/beta hydrolase fold family (pfam00561). Members of this family are restricted to the Proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	1.10993e-56
NZ_AP021888.1\|WP_173292338.1\|256006_258271_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_AP021888.1\|WP_173289898.1\|270169_270664_+\|SH3-domain-containing-protein	gnl\|CDD\|310737	pfam06347, SH3_4, Bacterial SH3 domain. This family consists of several hypothetical bacterial proteins of unknown function. These are composed of SH3-like domains.	6.38439e-06
NZ_AP021888.1\|WP_173289894.1\|268283_269312_-\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	6.48665e-160
NZ_AP021888.1\|WP_173289886.1\|259775_261752_+\|TIGR03545-family-protein	gnl\|CDD\|274640	TIGR03545, TIGR03545, TIGR03545 family protein. This model represents a relatively rare but broadly distributed uncharacterized protein family, distributed in 1-2 percent of bacterial genomes, all of which have outer membranes. In many of these genomes, it is part of a two-gene pair.	9.04541e-122
NZ_AP021888.1\|WP_173289876.1\|255162_255717_-\|TRAP-transporter-small-permease-subunit	gnl\|CDD\|227011	COG4665, FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component [Secondary metabolites biosynthesis, transport, and catabolism].	1.53063e-39
NZ_AP021888.1\|WP_173292337.1\|249309_251328_-\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	4.32936e-97
NZ_AP021888.1\|WP_173289902.1\|272563_273847_+\|outer-membrane-protein-transport-protein	gnl\|CDD\|224978	COG2067, FadL, Long-chain fatty acid transport protein [Lipid metabolism].	1.3081e-07
NZ_AP021888.1\|WP_173289900.1\|270673_272545_+\|M48-family-metalloprotease	gnl\|CDD\|320692	cd07333, M48C_bepA_like, Peptidase M48C Ste24p bepA-like, integral membrane protein. This family contains peptidase M48C Ste24p protease bepA (formerly yfgC)-like proteins considered to be putative metallopeptidases, containing a zinc-binding motif, HEXXH, and a COOH-terminal ER retrieval signal (KKXX). They proteolytically remove the C-terminal three residues of farnesylated proteins. They are integral membrane proteins associated with the endoplasmic reticulum and golgi, binding one zinc ion per subunit. In eukaryotes, Ste24p is required for the first NH2-terminal proteolytic processing event within the a-factor precursor, which takes place after COOH-terminal CAAX modification (C is cysteine; A is usually aliphatic; X is one of several amino acids) is complete. Mutation studies have shown that the HEXXH protease motif, which is extracellular but adjacent to a transmembrane domain and therefore close to the membrane surface, is critical for Ste24p activity. Several members of this family also contain tetratricopeptide (TPR) repeat motifs, which are involved in a variety of functions including protein-protein interactions. BepA has been shown to possess protease activity and is responsible for the degradation of incorrectly folded LptD, an essential outer-membrane protein (OMP) involved in OM transport and assembly of lipopolysaccharide. Overexpression of the bepA protease causes abnormal biofilm architecture.	1.37589e-51
NZ_AP021888.1\|WP_173289874.1\|253766_255143_-\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|227010	COG4664, FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component [Secondary metabolites biosynthesis, transport, and catabolism].	1.23286e-145
NZ_AP021888.1\|WP_173289904.1\|273858_278913_+\|tandem-95-repeat-protein	gnl\|CDD\|380078	pfam17963, Big_9, Bacterial Ig domain. This entry represents a wide variety of bacterial Ig domains.	3.7513e-17
NZ_AP021888.1\|WP_173289883.1\|259272_259764_+\|DUF2062-domain-containing-protein	gnl\|CDD\|200289	TIGR03546, TIGR03546, TIGR03546 family protein. Members of this family are uncharacterized proteins, usually encoded by a gene adjacent to a member of family TIGR03545, which is also uncharacterized.	1.86307e-47
NZ_AP021888.1\|WP_173289907.1\|278947_280765_-\|EAL-domain-containing-protein	gnl\|CDD\|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	1.51297e-98
NZ_AP021888.1\|WP_173289896.1\|269389_270076_+\|ComF-family-protein	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	6.11191e-48
NZ_AP021888.1\|WP_173289888.1\|261788_265013_+\|PAS-domain-containing-protein	gnl\|CDD\|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	1.38326e-74
NZ_AP021888.1\|WP_173289872.1\|251570_253700_-\|EAL-domain-containing-protein	gnl\|CDD\|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	2.70843e-91
NZ_AP021888.1\|WP_173289890.1\|265312_266239_-\|malonyl-ACP-O-methyltransferase-BioC	gnl\|CDD\|273953	TIGR02072, Malonyl-_O-methyltransferase, malonyl-acyl carrier protein O-methyltransferase BioC. This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	6.55852e-77

>NZ_AP021888.1|WP_173289888.1|261788_265013_+|PAS-domain-containing-protein
MRKNLPITQHEYVIPEGRVLVSETDLLGNITYANDTFIEVSGYSWEELNGQPHSMIRHPDVPEAVFKDLWDTLKRGEPWHQYVKNRRKNGDHYWVEANIAPVLHHGKVTGYKSVRNTIKREQIPQSEAAYQAIAAGKIILKSGVPTTPFAEKMAALSPLPKKSILGKTMIPLILMAILWSIVLQLYLQNVADNLYQEAVHDRQTLLSSNLDSEIASQSQIALTNAVGLAGNSALIYGLYDHQKTVIWQILEVNYQQYVKRANMDGMGLAVFDADLNLVSGSGVSIKVDAMPKEPLTRIQFQAEGGFLQALVPVPYGDKVIGLVGVSLPLTQVSALEKQANHQYAAFAKQQTTYQAAQGFENSPALQSFQLLKPQEQQDLFKSLYLVKNNHLFIWSPVEAGGQIVGAQLIVEPMEILSRLLSNTYFMIYVAQAAMSGGFILLLIQVFWRLRKFILTPLKNLTDKLKIASEQGSLSVRADVLTTDEIGQMGENFNHYVTAVQHLMISVSDMIDELAKGRLSKRIQADTKGDLNILKNYVNDSADNIQFVIKEIESAIHAIRDGHYSFDSSQTFRGEFAVMMEDLKLAMNDTHDAVVGINTTMKSIAEGNFSRRLNAQLSGELEALKTNINASLDQLESGITEAVEVLVAQSEGDLTQRVQGKYSGKMGVMAEAVNTSLDNISSAIAELMSASHTVNDASAQIAEGSSNLSDRIQSQAATLQETVAAMEVITDTVRKNAENANEATLLASAAKQQADNGSLVMQRTKDSMANVAQSSQKIADIIGLIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRNLAGKSAEAAKEIRGLIENTGVQVRQSVSLVESSNKEFMSIVQVILKMHEFIAQIASANQEQTRGVEQINLAMEGMDSVTQQNAALVEETASAAQTLRNEADEMKGQVSFFNTKSSELGAGVNRSHAVIQSFKFHEKSTGPEAWDMALAERALRNWVNKLKASLNGVGQITREELSAKTGMTHWLAQEGRDAFGSLPEFALLQQLYPSLRSEFLKTLDLKESGKLEDAQLHFIVVKELSAAVLDILDKLEAQLH
>NZ_AP021888.1|WP_173289886.1|259775_261752_+|TIGR03545-family-protein
MTQTAIKNPSPTSAAPAPASTPAPKGWIRWSGIAIFSAIIGGIVGLSYLGISLFLKKEIQHYASQAWGAQVDIGSLGLSFSPLGVEVNQIALTDPEQPMQNLLQIQQIKATMNLYHWVVGRTVIEDVNFNGFAMHQPRQSAGAIYKTAEETAAQKADKKASQAFNLPQMSLPDPQEILARETLKTVTAGQEIQAEIAKIDQAWSNLQAKLPNEATVKDYQKRFEALSKGDFSNPAVILQKQKDFEALKKEIEAHKKTLDEGQALLKQVNALKTQAQKLPDLPQQDYDRLMAKYSFSEQGLSNVTYLLFGPKIQGWLDTAQAWRVKLQPVIEYAQSWQAKRAKEAAEAEATKAARAFGTVVNYREYDPQPKFIVKRIHGDGNIDWGHVELAIKQLNFDHAVSKIPVTFKIDALPVKQKSPLIIMGESNYVHPEKPINRANFTLADYALSEARLSDDKTLPVVMKQGQMSLQGQMSWLGGDQIKADVDTRFSQVALDATASDSKEVKKYIAPIFADISEFTVQSAITGDAFAPKVDAKSDLDKLLSKAFNKVLDAEIASAKQQVKQYLDTLLNEQMGPINQQLSKLLGEQSTLKAQDLDLDAILNGKLPGLDQKSLEKKAKAEAEKALEKEKEKLKAQAQAEAEKAISDKAKNILKGFGF
>NZ_AP021888.1|WP_173289883.1|259272_259764_+|DUF2062-domain-containing-protein
MGLILKLFKALNANQYPGQIALSFVLGMILGLTPLFFAHNLLTLALIFMLRVNLAGVVVAWAFFSGLAYLLDPIFNQLGLWVLQMPALEPMFTEAYNSAVWRFLHFNNSIVMGSILVSYLLAIPAFILFLILIKTYRKTFLAWVSKFKVVQMLKAADKASLVS
>NZ_AP021888.1|WP_173289881.1|258340_259192_+|hypothetical-protein
MRLLGVLPLAAIVFLQGCDLGIEDKKTSAPVAQVTSTELKALFESFILIQDQEMMLTNLATQLQGVDTVSSVAGLLTNTSSTGVCGGTSALSADLTAVSGDFDNTLTLNSYCTDSLDWTGKLTQSGVVTATGSDADNYEMVYGNYIYKVESDDAFTVTLVGTMEKAVTATATTHYFNRISAYKYPDNLTVEALKWLVATYDAGKIYTGSLVHPTYGTVAVTTVPSFPVTTTQDGPYQKPISGKLKLTGLDSIGYITFNGLGSYTLDVDADADGIVDLTETLSW
>NZ_AP021888.1|WP_173292338.1|256006_258271_+|primosomal-protein-N'
MCVTIIEVAVAGPFLTPLSYLLDSTATAALPVVGGRVRVPFRSKSLVGVVMAVQTFVDEQALQAGCAALSLNLKKLKSIEAVLDTAPLFSAKDMELLKWASFYYHEPIGNVMQTALPKRLRQGEVPEVEGVTSWVLAPQSIRETLPPLPANAKQQLALIDCLSESQALSAEHLNAQLNHWRTPMKRLLDLGWVQETTSPCLNWHSKLTRPGHILNAEQQVAVDAVDFDKGYQAFLLEGITGSGKTEVYLGMIERCLHLGKQVLVLVPEIGLTPQTVQRFEAYLQQPVAVMHSGLNDKERQCAWWLVQSGRVQVLLGTRSAVFTPFANLGLCIMDEEHDLSFKQQDGFRYSARDCLVRRAHLEKVPVVLGSATPSLESLYNAQTQRYAWLKLQQRAAGAQLPNVQLLDIRGEKLAEGVSTPLRKLMAQHLADQGQVLLFLNRRGFAPVLMCHDCGWQAACPSCDANMTYHQQVNELRCHHCGYQHKAPHTCPHCQSAEFVKVGQGTERLEETIQSWFPEESLLRIDADTTRLKGQMAELTQQAKEGKARILIGTQMLAKGHHFPQVTLVGLLDIDQGLFSSDFRAAERMAQLIVQVSGRAGRAEKTGTVMIQTHHPEHPLLKTLVAEGYEAFAKQALLGREEAGLPPYEYQILIRAEAIDAQAGWQFLNEIKFSLQSLKPTLLAQASSQVNAQVMGPVAAPMMRRQGRYRYQLLLQSNHRGTLHQWLGQVESRIYASKLTAKVRWSIDVDPQEMN
>NZ_AP021888.1|WP_173289878.1|255713_255908_-|hypothetical-protein
MKKSLTNTLLLILLPIAFSLSSCSQDDDSHSQATPSAQNADKNQEARGVKQTPLPTGPQLKDRL
>NZ_AP021888.1|WP_173289876.1|255162_255717_-|TRAP-transporter-small-permease-subunit
MKTWLTLFIHQQNRFQKMLGHFVAWGLLSLVVLSASVVILRYGFDAGAIALQETVLYNHALVFMLGMGYALQQDKHVRVDVFYETMSPKRKAWVNLIGALFLALPTLLFIAWASWEYVEVSWRIHETSSEPGGLPFVYLLKTVILVMAALVSLQALTLAAESALQLTDSTPTPSETPEASSAKL
>NZ_AP021888.1|WP_173289874.1|253766_255143_-|TRAP-transporter-large-permease-subunit
MEYIALGLFALVLIALMFGFPVAFTLSGVSLIFALGATLFGAFDMAFLNSVPNRIFSIMNNTTLLAVPLFVFMGIMLEQSKIAEQLLTTMDEVMRGFIGGLGISVILVGALLAASTGIVGATVVTMGLLALPTMIKQGYCPKLATGTICASGTLGQIIPPSIVLILLGDVLSSAYQQAQLNQGIFSPETLSVGDLFIGALLPGMLLVLFYILYVFGMAWLKPETAPGLSSASIPAGIWTRVLGSLLPPLVLIILVLGSILGGFATPTEAASIGALGALVLAALKNRLNLAILNQVMRDTLMVTSMIFMIFIGAAFFSLVFKGLGGDDLIHGLLADLPGGVFTAMLLVMVFMFVLGFFLDFIEITYVVVPIVAPILLMMGIDPIWLGIMIAINLQTAFLTPPFGFALFYLRGVAPQGVKTKDIYLGVMPFIGIQLLVLCLIAYWPELATWLPAQQSNSY
>NZ_AP021888.1|WP_173289872.1|251570_253700_-|EAL-domain-containing-protein
MQNTTLEAELKSTILRLKNERQFKRDIINALHDGILVFSQHLSLQIINDAAQSLMCFNPNSDEFFVDLEFFKNKKRTIKFNMKRWLEQVIDAAQNIPKETYIWVKPNCSEEPSTPVLLSAKPILNTDGSFQALLLVVYDQTIYAHSDEQHRILEAAFNSYDGQFITNEKGYIIKPNFSFSAYTGLLPTELNSMTIIHWMKKQVTLKDSIQIEDILKSLLLDKKWSGEVQIHPNPETTFHAVLSLSMLMDNDKNIEHYVGTLQDITDIKESQANVERLAYFDDLTGLPNRRLFIEHLEKDLLHHKRNHTYSALLYLDLDNFKEINDIYGHAVGDAALKQTANTLTELLRAEDLVARISGDEFIILTRYKVLSRDLAAQHALTLASKIIQTLNQDLLIEEHIIPNASSVGIHIIPGSADETPEYLISCADLAMYEAKQRGKNQLYFYQTELTEKILRRREIEEALKHANYDQEFYLVYQAQVANHSQQISAETLIRWQHPILGNIRPDQFIGIAEDTKQILKLGQWILEKAFTQTYQWNQKSATPVHLSVNISPIQFHEPTFVDCILEIQRKTQVNPQHITLELTEGILISNIEDALTKIKALAQLGYQLSIDDFGTGYSSLSYFQKLPIHELKIDQSFVKHLPGSEEDIAIIETIIQLAKSKNLTIVAEGVETEAQVDFFKAHQSAILMQGYFFSHPETAQEFEKQFLTL
>NZ_AP021888.1|WP_173292337.1|249309_251328_-|EAL-domain-containing-protein
MVLFDETYHPLHANPAFFNWHPQQALDVLQDPLWLCTHKRGELAFNLQDWLANPHNETSQTLWLKMPNRSSRRPIQLQRHLLKTQDNTEHTLLVIQDLSLHIQLDAQQKLMNASYAGQFITDAQGLITQPNYAFCAYTGLTAEQLQKMTYIDWLQKQVTFKVPFNSIMRALLDEQSWSGEVQIFASKEARFSAILSLSMLVDEANNVEHIIGVLQDITDILEAQSEINQLAFYDKLTGLANRTLLQERIERVFENCQQHQTFGTLFFIDLDGFKIINDTFGHNAGDQLLVQVAERLLPLVGEKATLARLSGDEFMVLCPNATQDRDIAFQDALAFGGKLLDAIDSRYKIEQHSIHSAASIGICIFPTAEDHLQSRSDQIISYADMAMSEAKKLGGNQTYLFEKSLIEEAKQRLELIEALNHSELDDEFQIYFQAQVNKAGETISAETLLRWFHPELGFVSPAKFIPVAEEGRQIIKIGLWVMHKAFLQAKAWNKKYRPIRIAINISPIQFHEQSFIELIIGLMKFTQVDPRTITLELTEGVLIRNSKLALQKIQHLVSLGFEVSIDDFGTGYSSLSYLQKLPIHELKIDQSFIAQVPGNPDDEAIVDSIIQLASTKNLKIVAEGVETQAQSDFLTQKYDQVLLQGFLYSRPLPAADFEERYIKPQQVSSKIA
>NZ_AP021888.1|WP_173289890.1|265312_266239_-|malonyl-ACP-O-methyltransferase-BioC
MQTFNRAHIRQHFDHAAVSYDEAAVLQRQVADHLDERLDLIAIQPQVVLDVGAGTGILTQKMRARYPKAQVMAVDLALGMLKKAQHHYQQQRSFGQKAKSLFSSEQQHFINADAYALPLASGQVDLLVSNLMLQWCDDLDAVFQEFRRVLRPEGVLIFTTFGPDTLKELRQAWSKTDQKAHVNTFIDMHDIGDALIRNGFGQPVMDVEDFVLTYDKPIGVLKDLKAIGATLANQDRGAGLMGKQRFTQMLEHYEAFRAPRTDQKIPATYEVVHGHAWAAQEVIKGPNRDRSGLVEISLDQFKSGLKPI
>NZ_AP021888.1|WP_173292339.1|266244_267033_-|pimeloyl-ACP-methyl-ester-esterase-BioH
MLPSTQPHAEHLTLVHGWAAESAGWADWAQEFLTPHFQVHLIDLPGFGQSPELSKTQIANDLNGAWCDALAQALPPKSHLLGWSLGGLLCQQLAWQYPRQVQSLICLASTPRFTQQDGWPNAVSPELMANFMKALGVESLTLLKQFWNLQLQGSDNARPLMKQLSAQMRNRNLPSLAGLTQGLKLLRDLDNRPHLQDITQPTLWLFGEHDPLIPQALQTQLHDLQPSAQLHIIKGASHMPFFSHPQDTADALIHFIHAQIET
>NZ_AP021888.1|WP_173289892.1|267072_268269_-|8-amino-7-oxononanoate-synthase
MNKPSIEQRFAPLLQARQAQNLYRARPLALSAQQPSMQINGKQVINFSSNDYLGLANAPELKNALQQTLSQNLSVGSGAAHLVTGHSLEHHLLEDELADWLGVERVLLFSTGYMANLAVQQVLMQKGDLILGDKLNHASLIDGALQSDADFKRYAHNDMSALEKRLSKTQHADSATLIVSDGVFSMDGDLTKLPELQKLAKNNQAWLFLDDAHGFGALGKHGKGCFEYFDCQPDTNTILMGTLGKAFGVSGAFVAGSQTLIETLINFARPYIYTTAMSPMMAAAGREALRLVKQADARREHLNQLIQQFRIGASQLGLPLMDSPSAIQPIVLGDAATALAWSEQLKQQGFWVGAIRPPTVPHNTARLRITLSAAHTAEQVDSLLEALAACQHSHTLSR
>NZ_AP021888.1|WP_173289894.1|268283_269312_-|biotin-synthase-BioB
MTQAAPFGQIRNDWTLEEIKQIMNQPFNDLMFQAQSVHRMYFNPNEIQTSTLVNIKSGGCAEDCAYCSQSARNQTDLEKQQMLEVQEVIEQALVAKERGATRLCMGAAWRNPTKKDFPRVLEMVRVVKDLGLETCLTLGMLNDDQVAQLKEAGLDYYNHNLDTSEAFYPKIITTRNYQDRLDTIDKVQKAGINVCSGGIIGMGEEHKDRAELLRTFATMRFHPNSVPINLLVAVEGTPLAHMKDKTDSFEFIRVIATARILMPQTYVRLSAGRMSLTDEAQALCFLAGANSIFYGDKLLTTENPESDHDLMLFAKLGIKMQENAEAKLQSQKMAEQITELTA
>NZ_AP021888.1|WP_173289896.1|269389_270076_+|ComF-family-protein
MNRLERWVFPPTCVLTHQKLSNNSQFDLAQAILEGFSQTQAVCPICNEATPNAQVCGACLTQKPSFDVTLTAFDFEGDLRELILQFKYQPALHLGKLLADISVHHFKGRAVDALLPVPIHLERLLNRGFNQSTLLARHWGKQLNLPVITDAIERIKATETQTHLTAKERQENLKGAFAVNVAALAGCKSIALVDDVITTGATMQAIAGVLKTHLPALRIEAWAVAKTR
>NZ_AP021888.1|WP_173289898.1|270169_270664_+|SH3-domain-containing-protein
MKYFSVLFTVLLMLSPPTFAESQYIRSLQCKLMESPNFKAEVVATLSQGLEVSVLEKKGVWVKIETPEKISGWVSKFLLSPVKPDENATSILDFKEEDLNNVRQRASVITTAAAARGLTAKEVSDGVNTPVVGGQNFDALKLMESYRPSDAEIEAFIRSIPMSK
>NZ_AP021888.1|WP_173289900.1|270673_272545_+|M48-family-metalloprotease
MKVILRLLVLGLLSSLSLQVQALQNTRMSVLEAADEWTPQDLEAEIYFGRNLAAKMLGQSPLYADEVAQGYVNELGASLAKNSNRPDLKFYFAILDDEQINAFAAPGGYVFITKGAIEFCENEAELAGILAHEIGHVTERHIVKQLKIRGKNADQMTGLMSSMIMGGGQTLTSAFSMAMDEALDTWKGAGLKDRKDEYQADQISTEILLKTGYDPKALAGYLARVSEHKEEVKDRVRTHPPFHLRIKAIEQQLYGTKPLDQFENPQRLNNNLASIFKYVEEETLAKNLFLYAPPLESESFQSYLNQMNGAVNAVQGKKNVLPVFAVLSDEVFYKRYDYFTVISSGLLSQLENEAQLASLLTVFSIPEGQKNIDDAISMAMINLGYNPMAWVEVLSHFEAQIQDFEFQNAKVRSQQLRKDLSDDGALNQKRWQEQFKFALAETVEKGILPLAYMAQIDASEKRNRYLNLVAYSIAKAIGYENFNGLLVIQSDLPMMRLQVNQVLLSSSVLNELNNEAELAGLIANTMLYGLNRRQNLQKHSDEIYLEADSSTMSLLNELGYGPAHWLAYLKARETKGSSEFKNLINQSNIDDRTAILTQKTQGRPAWKRFGQSHEQRFKEYMKS
>NZ_AP021888.1|WP_173289902.1|272563_273847_+|outer-membrane-protein-transport-protein
MKYKSTAILFSSILLLISTKVYADQYHYSDILIGDRAAGFSGAYTAISDDPSGLYYNPAGIVRAPDGQLSASANAYNQTAYKYSNINAGGHTWERKSNANIANFFGAFQPFGEFMVGFSIAVPDSNKASQDESFHNYEAADPNWTIQDEIINYKEDDTTLLFGPSLAYKLNDKLSLGATLYIHVRNDEFTFRQETRASNNASGDIVYDILFQKYKTNEMGLKPMLGVMWDASKTFSVGATLAQTFMLSQDPMAQNSQITNASIDKTSGVTVITKVGNNVDAGNYFPVGMSKAPDRQLPLEAKLGFAWFPDSRLIVSTDIQYYGETSDYASVLNIAGGMEYFFSPKISTRFGLNTNNSNNKSLNQPGFDVDMLGLTWSLSQHNRLSALTFGLNYSQGTGKARLLEGSNRIQDLTVQSLTAYIATSMNF
>NZ_AP021888.1|WP_173289904.1|273858_278913_+|tandem-95-repeat-protein
MNCKLHYPKVFLISLFIGGLSGCDSPSKLDAEGIGKYISGVGNIVMSGLVVDPAIGGATVYIDANGDGVIDDNDPQAQTDSLGYFNYNPVTNVDYCAVGPSAYCFPMKEEYAGQVLRSSGGTDLVTNKPFEGEMQLKLSSEVNENQTEGIVITPLSSIVAFMTDEQKASLKSLLNLNESDDLNKLDPLDFSDAKYPTAEDKAKQQQRLKIIVNIQNTVQALTSALATSDKTQNNALNEAVYAVVAQNVTSFTTDLQRADNQPTNTDNSVDSLLDKVIIQVSQSTKVSNAVKTQAQSLSTTSPNANPTTRNALLNNVSALSAASNNVFNTTTITTNANASKVLFKTEVVGETVNATPFDITNTQTAITIINSTVVNNLIDGSTADFTQLTNIAITQNITSEEELGGIIDSGVGTGDPVPGNTDIGTTTGDGTTTGDGTTTGDGTTTGDGTTTGDGTTTGGGGTTIPPITNTAPVAVDDSITAIEDTVFTSTIDLDANDTDLDSNTLSVVAGTFSTAQGGTLILASNGSYTYLSATNFNGTDTVDYTVTDGALTDIGTLTITVEPVNDLPTANGESITVSKDVEYISSTVNLLANDTDVDGDDLSIVSGTYTTQAGGSITLNANGSFSYTPAANFNGTDAYVYEVSDDGGVNASATLTIIVTDAMSDADETVTTAEDTALTGNVMSNLTDADSSSHSVTSFTVEGQTYQPGSTATITGGTITIAATGAYTFTSSENFNGSVPAISYAMVDNTDANDTDTSTLNISVTAVTDAMSDADETLTTAEDTALTGNVMSNLTDADSSSHSVTSFTVEGQTYQPGSTATITGGTITIAATGAYTFTPSENFNGTVPAISYAMVDNNDATDTDTSTLNISVNSVDDVPVAVEDNFTLNEDGAITDTLATNDTLSGDGGNVFTKATDPAHGTVTVNADGTFTYTPAANYNGADSFSYTITDADGDTSTAVVNLTVNSVDDVPVAVEDNFTLNEDGAITDTLATNDTLSGDGGNVFTKETDPAHGTVTVNADGTFTYTPAANYNGADSFSYTITDADGDTSTAVVNITVVAVTNAMSDADETLSTNEDTALSGNVMSNLTDADSSSHSVTSFSVAGVATSYTPGQTATIVNLGTITIATNGDYTFTPAANFNGSVPAISYAMVDNNDANDTDTSTLNITVDAVNDSPVALLASTSSPIIGNPFDLESGLTAEGLIELDNHKILIYGLDKINNKLYISRWFANGRVDTTYGTDGILTVNVDANAEIDAVKQSDGKVNFLIAYPTAGAAQIKIMQLDSEGVVNITFGTSGVKQLSIINSPSTFTQVRLLMQGTKMIVLGLDDSSNTLVMRLLSTGVYDTTFGDSSNGLAYGEGFLDNLSDVVIGSDDTIYYMGAYNSDIFISKLNADGTINAAFNSNARLELIIDALGVFTASNLVLDGSALMYLLAYKDEDSNNKLILGKVSAADGSAVIDSYFSLGYKILDLSDAPQMFPTSVEMLPNNGLLIGGYNPNTVNSISNTLKLAKFNYSTGDLEYSFSGNAGVYISQSVGKVSDIALIGTNNDEIWMLGDRLSESVGNNGTFNITRLDLGGVVVNYDLAYDVNNGVLPTAVSVSIPAFDVEGDNFTYSLLGTASNAASVTLDSATGELSYSNDNCYAAGTQVDGLGHYYDLVDFNMTDSQGATSSTQTFTVRLFNCGA
>NZ_AP021888.1|WP_173289907.1|278947_280765_-|EAL-domain-containing-protein
MNFKQILSNINAGVILISTANDSYEILYSNEWIEAYAKKSITPGTSLFEAFELSQSERAMLNRKVKSALFLNAPSFLSAEHEGYLIPITNQKITRADTFPFMQQDAAIMPYDAEKQQVALIIYDFTSLMISQRDLRDKQQELEEAIKELKKAHKNLAEKTALIDYQANFDSLTGLANRVLLQDRFERAITAAQRTQTLIGAIYIDLDFFKPINDTYGHSTGDKLLKMAGDVISLSVRKSDTVSRIGGDEFVVLLPNINDLAPVIKIAENIINKLGHPFTIGDHHLRLSASLGIATYPANGDNPSTLIKNADIAMYHAKRIGRNSYQIFEDYFAEERMAQTNLEQALRKALSDPNFIAQKGFSVVFQPKVKHLEQGAIKTVGVEALIRWAHSEHGVVSPEKFIPLAEAAGLVSKITQFVFHESCKHLKLWRVIEPDFMVSVNLSAYDFDRPNFCQELLETLKYYGLPPSAIDLEITEHNALLVKQDNYRKLNDLRNFGFKLSLDDFGTGYSSLSFLAQIPVHTLKIDKEFVYKTQYSPTDKAMLESIIKLAHSFKLDVIAEGVETIENLEQLASFGGNYFQGYFFSKPLEADAITVRLQKEKEQRF

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Crispr_ID: NZ_AP021888_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP021888_2

2244320-2244413

Orphan

Consensus_repeat	Method
TTTATTGATTATGTTTAGTTTAGCAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP021888_2

>merge|NZ_AP021888|2|2244320-2244413|CRISPRCasFinder
TTTATTGATTATGTTTAGTTTAGCAGAATATGGAGTGAGTTGAAAACAAAGTGGGTGTCCTTTAGTTTTATTGATTAAGTTTAGTTTAGCAGAA

>NZ_AP021888|2|1|2244320-2244413|CRISPRCasFinder
TTTATTGATTATGTTTAGTTTAGCAGAA	TATGGAGTGAGTTGAAAACAAAGTGGGTGTCCTTTAGT
TTTATTGATTAAGTTTAGTTTAGCAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP021888.1\|WP_173292023.1\|2246844_2247171_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292513.1\|2243233_2244157_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173291937.1\|2249954_2251172_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NZ_AP021888.1\|WP_173292019.1\|2240948_2241731_-\|SapC-family-protein	unknown	unknown	gnl\|CDD\|377801
NZ_AP021888.1\|WP_173292029.1\|2255916_2256879_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292030.1\|2257065_2258514_-\|FecR-domain-containing-protein	unknown	unknown	gnl\|CDD\|377406
NZ_AP021888.1\|WP_173292015.1\|2235121_2236237_-\|tRNA-(uridine(54)-C5)-methyltransferase-TrmA	unknown	unknown	gnl\|CDD\|235332
NZ_AP021888.1\|WP_173292028.1\|2252533_2255734_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236140
NZ_AP021888.1\|WP_173292021.1\|2242897_2243131_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292013.1\|2233485_2234028_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|99749
NZ_AP021888.1\|WP_173292027.1\|2251242_2252142_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292018.1\|2239559_2240888_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|273829
NZ_AP021888.1\|WP_173292017.1\|2237776_2239480_-\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NZ_AP021888.1\|WP_173292025.1\|2247876_2249079_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NZ_AP021888.1\|WP_173292014.1\|2234357_2235125_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NZ_AP021888.1\|WP_173292020.1\|2241869_2242694_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292024.1\|2247298_2247769_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NZ_AP021888.1\|WP_173292026.1\|2249251_2249932_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292016.1\|2236334_2237762_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NZ_AP021888.1\|WP_173292022.1\|2244620_2246603_-\|calcium-binding-protein	unknown	unknown	gnl\|CDD\|369942

Protein	Function_ID	Function_description	E-value
NZ_AP021888.1\|WP_173292015.1\|2235121_2236237_-\|tRNA-(uridine(54)-C5)-methyltransferase-TrmA	gnl\|CDD\|235332	PRK05031, PRK05031, tRNA (uracil-5-)-methyltransferase; Validated.	0
NZ_AP021888.1\|WP_173291937.1\|2249954_2251172_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.36528e-120
NZ_AP021888.1\|WP_173292019.1\|2240948_2241731_-\|SapC-family-protein	gnl\|CDD\|377801	pfam07277, SapC, SapC. This family contains a number of bacterial SapC proteins approximately 250 residues long. In Campylobacter fetus, SapC forms part of a paracrystalline surface layer (S-layer) that confers serum resistance.	1.83785e-57
NZ_AP021888.1\|WP_173292030.1\|2257065_2258514_-\|FecR-domain-containing-protein	gnl\|CDD\|377406	pfam04773, FecR, FecR protein. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm.	7.87903e-12
NZ_AP021888.1\|WP_173292028.1\|2252533_2255734_-\|hypothetical-protein	gnl\|CDD\|236140	PRK08026, PRK08026, FliC/FljB family flagellin.	1.94065e-07
NZ_AP021888.1\|WP_173292013.1\|2233485_2234028_-\|Uma2-family-endonuclease	gnl\|CDD\|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	4.68596e-31
NZ_AP021888.1\|WP_173292018.1\|2239559_2240888_-\|TolC-family-protein	gnl\|CDD\|273829	TIGR01844, Proteases_secretion_protein_PrtF, type I secretion outer membrane protein, TolC family. Members of this model are outer membrane proteins from the TolC subfamily within the RND (Resistance-Nodulation-cell Division) efflux systems. These proteins, unlike the NodT subfamily, appear not to be lipoproteins. All are believed to participate in type I protein secretion, an ABC transporter system for protein secretion without cleavage of a signal sequence, although they may, like TolC, participate also in the efflux of smaller molecules as well. This family includes the well-documented examples TolC (E. coli), PrtF (Erwinia), and AprF (Pseudomonas aeruginosa). [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Porins].	3.727e-38
NZ_AP021888.1\|WP_173292017.1\|2237776_2239480_-\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_AP021888.1\|WP_173292025.1\|2247876_2249079_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.04555e-55
NZ_AP021888.1\|WP_173292014.1\|2234357_2235125_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	6.74138e-34
NZ_AP021888.1\|WP_173292024.1\|2247298_2247769_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	5.24555e-05
NZ_AP021888.1\|WP_173292016.1\|2236334_2237762_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	8.76561e-101
NZ_AP021888.1\|WP_173292022.1\|2244620_2246603_-\|calcium-binding-protein	gnl\|CDD\|369942	pfam08548, Peptidase_M10_C, Peptidase M10 serralysin C terminal. Serralysins are peptidases related to mammalian matrix metallopeptidases (MMPs). The peptidase unit is found at the N terminal while this domain at the C terminal forms a corkscrew and is thought to be important for secretion of the protein through the bacterial cell wall. This domain contains the calcium ion binding domain pfam00353.	4.75168e-05

>NZ_AP021888.1|WP_173292513.1|2243233_2244157_-|hypothetical-protein
MMQLANVFAIDIAAYAIMNNHYHLVARVNQEKAQAWSNLEVLQAWTQLFASNITVQQYLQSPETADEAIVKQVNDMADIYRKRLYDISWFMRVLNESIARMANKEDQVTGHFWEGRFKSQALLDEKALLSVMAYVDLNPVRANIALSLEDSDFTTIQRRIKNTEDFPEPALVTQEKPCEVINQQQKLENAFLQRLDQIPRASLMAFDANALNNQQIPFAKPDYIEFVNYLGQALHPYKKGFLSSTQKPNPLMQKYKLTPEIINVICQGKLLKSFGAAIGDIKSLQRHQAHQQVKYQKGSGVAKMMYG
>NZ_AP021888.1|WP_173292021.1|2242897_2243131_-|hypothetical-protein
MNAIKINEKDYNLEDLSDTAKQQLANIQAVDAELARLNSKAAIYQTARNAYVNALATEVEATPSTKPVAKKTAAKSK
>NZ_AP021888.1|WP_173292020.1|2241869_2242694_-|hypothetical-protein
MVELVNSSMFAFNTLPVSKGNDDNDIGAGSFNDLLDVETKSLATKDVLSQVDASTSLVTDALTAKVYRPDMKHFMDATGLNAADASEILYGVVGSNVDTRNWSAIMASDDPVSMARKATGEMYNVGYSYNLDAYNVDKVGSGKVAQSGNFVLQQQFDGDGKVTSQGLRLIDGQGNLLRDAGNDELQIKRNAWLFGFDTAPLQALIEPAQLISQDLSDAINQVVKNDEIFTEVKVQHESSGALSEASDLLDSEGELFNQALALVSAQLNLERSIE
>NZ_AP021888.1|WP_173292019.1|2240948_2241731_-|SapC-family-protein
MATWVAVSKEKHKNAGWKKFSNYSFAQVDAVTPVLLAELMHLLPYYPLAFTQNADGQYQLVVVQSLQAGVNLFVNKAGQWMAPYVPSSYRGYPFLLIPQGDQLILCVDESSENFHAELLPGDTPFMQADELSDELQSILNFHNSRSQNQKITQELVNKLSDSQVIVPWDIQLKPSNESDKAQSVNGLFKIDELKLRELDAQVLVDLNTSGALSLAYAQLFSQIRLKDFSQRYEYFNKMHQKPMDIDLDKLFGEDDDGLKF
>NZ_AP021888.1|WP_173292018.1|2239559_2240888_-|TolC-family-protein
MKKNFLIFMVLKLLTPAFAEAIEPKLNLSIDKAFEMTLENNDLLSSRKAQMVADQESLNQAWAGVYPSVSISGVYGAGEYSTTYTPNTSDTFNRYGVQIVQPIFSDRKFEYISRQSTFADYSKINYQFETQKTLLDMTYAFLDLAKSQRLVETYRAELEDHKVKFVGLEAMLERGLATKMDVLEAQAKQDDILASLKGAESTELQNRKKLERLLGGKTIQSVIIDETLWQRARKWVEFSNWSDLAKDASLNLRIARYNVQLAKQDSNLEKSSYYPEVNLRAAIDNTDSYESTFRDNKKIQLEMTWPLYEGGSTNSKVRASNQKILSQQLALQDAEKMLNVQINEVVTGLMSSVANIDALDKSVTSNKLYLDSAEKGLSYGLRGVFDILDAKTRIYDTERRMVNEIYGNLRGQFELLFLLGKLDEEHLSQYLQKDFTPDLLNP
>NZ_AP021888.1|WP_173292017.1|2237776_2239480_-|type-I-secretion-system-permease/ATPase
MKNIHEKTELEKALFNVKKAFYSVGVFSFFINLLMLVPPLYMLQVYDRVVTSRSENTLIMLTLIVVVLFITMGFLEFIRSRILVRVGNRLDQDLNADLFASMFKKSIKEPGQGGPQPISDMTSIRQFMTGNGPFAFFDAPWLPIYIAILFLFHVYFGVFAIFAALFLFGLAYWNEVSTKKILSEASNESIVSSQYAGACIRNAEVVSAMGMENNLRERWLQKHLSFLSKQSNASDKAGVIANISKTSRLMFQSLILGLGAYLAITDQVTPGMMIAGSIILGRALAPLDLMIGTWKSFGAARSAYERLNKMFADYPSQQRNMTLPDPVGAMSCENIVVTPPGSGIPVVRGVTFALNPGESLAIIGPSAAGKSSVARALLGVWPLMGGKVRLDGADVHAWNKDELGRHIGYLPQDIELFNGTISENIARFNHLDPEKVVAAAKMAGVHEMILRLPNGYDTFIAGNSGSLSGGQRQRVGLARALYDSPKLVILDEPNSNLDDQGEQALSVALEQLKQANATVIVISHRKPILKHVDKILLMANGMVRGFGKRDDVLMALQSGELSIADKS
>NZ_AP021888.1|WP_173292016.1|2236334_2237762_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MNQDKQTTLVKEKSSLQKHEVIDGQSVVKKDIDAFKHAKPSEQIQIDVDDKRFARLGWISLIIVFVIFGGWSAIAKIDNAAVAAGEVVVESSNKSVQHLEGGLVAEILVKEGDLVVKGQTLLKLSPTQAQAELSMIQSQLDESYGAESRLRAEQMGLDKIQWVDEMQARSNLPSILQIQNSQEAVFKARKEAKAGELSIYSERINALKQQISGLSEYLNSLQNRIDSYKAELIDWEALYKEQFTDKIRLQEMKRQLAQLQGEYDQNVSEIARLKVQITENTYQKILATQNFSKEVADELSKTLAQKVDLSYRKQVLQDKLNRVDIVSPADGKVQGLQIVTVGSVVRPGETIMEVVPQNEGYAAKVRVSPIDIDKVKVGLITHVRFSAFNTQITHVVEGQVINVSPDKFVDPKSGMEYFEAKVLITPKGIKQMEKDGMYMRSGMPVEAMIKVGDRTLLGYLMKPFTDMIARSFNED
>NZ_AP021888.1|WP_173292015.1|2235121_2236237_-|tRNA-(uridine(54)-C5)-methyltransferase-TrmA
MLCQVNPDAYSFQLEEKAQRLKRLVPSLSCFNVFESEPAHYRARTEFSIWHEGDLADYIMFDTDTKQRVVIKDCPMVLQSINDLMPKLMAEIMADPVLKLKLFEVDFLATLSGEMMVSLIYRKSLQKDPEFNQAWLNSAQELKEKLNITQLIGRARKEKICLDSDFVVERLQVDGKAFVYQQIENSFTQPNAGVAQKMLSWARQMAFNISADTPKRDLIELYCGNGHFSIALAECFNRVLATEISKTSVASAQWNIEANQISNLTVLKMAAEDVSAALQGESYNRLKDIDLASYDFGTIFVDPPRSGLDDLTRKMVCEFDHIIYISCNPDTLAFDLQSIQQTHELVASALFDQFPYTHHIESGVYLRRKTL
>NZ_AP021888.1|WP_173292014.1|2234357_2235125_-|sulfite-exporter-TauE/SafE-family-protein
MILAWIGALVIGITLGLLGSGGSILTVPVLTYLVGQETKLAIAGSLMIVGVISLFSVIPYARQKLVKWRTVVIFGVPGMAGAVLGAWLAHFVSDALQMLVFAVLLVTAAYLMYKPVKLKEDEEEHEERAIYKIAIDGLLVGAITGLVGVGGGFLIIPALVLLGGLSMRLAVGTSLVIIAIKSFAGFIGYLSVLEALNLTIDWHIIGIFSVIGVLGGWLGHKISSRVNQEHLKKGFAVFLLLMGAFILYKNLPGLF
>NZ_AP021888.1|WP_173292013.1|2233485_2234028_-|Uma2-family-endonuclease
MMAYIKLEDLPTYTYVDYLQWKGRWELIEGHPYAMSPSPVLEHQHKSGKIHAQLPLRLEGCADCQAVLATDWKIDNETVLCPDNAVVCHLQADDHFIIRTPAIIFEVLSPSTKRKDRNEKFHIYQEQGVSYYVMVDPATDLAEIYQLLNGRYHLVKETTREIFEFDLAECILKIDFSKCC
>NZ_AP021888.1|WP_173292022.1|2244620_2246603_-|calcium-binding-protein
MNVTGANITSLTVNATTAFTATLAADYAATAALTVTGAGAVNVGNAGTFKTVDASTNTGGLTMTLDTVTTSFKGSTGNDTVTTATLAAPAAGIIDAGAGTADTLVVAATADVASSALRGSYTGFEVLSNATTAAIAADGISGVTSLITAGDGAGFTGMSAAQAAAVTMTADQTGALQYALTTATGTSDVLNLTVKSATAATELDATGLNITGFETANFTVSSGGTSLYNAAGTTALTAGTDYTSLALGTATTDLTKVTLAGANAAKINLSANATKVTTVDASANTAGADIVIGGQTGTVVVTGTGTRDIVTMNAAGAGGLQTVNAGAGDDAISATQAVMAVATINGGEGTDTMTLTDAATLTLADNSFTNVTAIEKVVIGSATALTFSVGGFANALATANSGVLDVTASALTGAVTIDGTGLTGTNSMKLTLTNVDTAANATATTITLSQGADVVTMTAANNTQTDTITISGGVSALASTAAKTIDLSAVTGTSTGAISVTTGAGADVVKAAATAGTYVLGAGNDTFTGGAGVDTVTGGTGVDTMTGAAGADVFVFSDVDTDIDTSAGAVTDIITDFVTTSDTLDFTTAGLVGNYTEQLTAAASLDALLTAADTALNGTVKYYFGVVGSDGYLVYDADGIGYTSVIQMTGVTDMAFGDIV
>NZ_AP021888.1|WP_173292023.1|2246844_2247171_+|hypothetical-protein
MLALTAVAPTAPEASTVAVTPAAAARTLIVSIPVITAALRAVASVAVTTKFNVSVPAPPLIMSAAFKVSSVPPLEAIAVNVSLADEPVNAVPWSTPVVSDQIIDTVSI
>NZ_AP021888.1|WP_173292024.1|2247298_2247769_-|helix-turn-helix-transcriptional-regulator
MSSIYDGYQEFFDFVEHLRSQEIPSDEALEQDVERFLNGISQYGSFPDSDASKRFAEEVSFGLMTKSCRNLLNQSQQEFAKNVGLSKPTIARLETFETKPNSEMTERIIGYLNSEGLTISISGSEYQLSISPSVFIKSYLSMLKTSKRRSDRKVKE
>NZ_AP021888.1|WP_173292025.1|2247876_2249079_+|tyrosine-type-recombinase/integrase
MPKQLLSQAFVDKAKCPKGQTKVDYFDTKVNGLLLKVLTSGKTNYYLRYQNSYGRWTENRLSQVDASALNLNDARQLAKQYLSQITLGHNPFEDKVKKTSVITFQELIDNYYLPHIKGYKRSWDTDVSLLKNHILPALKDKHLDEIKRNDMVSIFTKHRSTHKPGSTNRIIILCRYIFNCAIKWEIEGAGQNPTSGIDLYQENNKLERYLSSDEAKRLFEELDKSQAKMLKPIITMLLLTGARKNEVLQAKWEDFDFERRLWRIEKNKTGTTRHVPLNDGAIQLLQSMTKHDSSEYAFPNPDTGKPYTQIFHAWNTVRKRAGLDELRIHDLRHSFASFLVNSGRSLYEVQKILGHTQIKTTQRYAHLANDTLVDASNAAFKALPLIQLQKLPEVPMVTMQ
>NZ_AP021888.1|WP_173292026.1|2249251_2249932_+|hypothetical-protein
MTNVKYGLNERLLKVLRVLKSDKTTSQTSYTELARLAQLSRQTINKHQTAIQHYLSDAPPPSNLDLMYVRRRQKETYVEYATAHLKLGDELFPAILGAIAGYQLRHEVKLISHLNKIDAIIELGKAFVQVANQVQIKKDNSGIVINSQNKAVKHLLNSGTKVAFVDKLFSRSKSYSSARYSKKWKLTKLGQETIQEIVKLALHEIRRINADLCSQLTVSPLHRACK
>NZ_AP021888.1|WP_173291937.1|2249954_2251172_-|IS256-family-transposase
MSNLDHKKLQELAKELAKSVKTQEDLSNLSSMLVKMTVEAALGAEMEEHLGYSKNQVSDSTNSRNGYTSKILKGDHGEVELSVPRDRNSTFEPVIVKKGATRLTHMDDQILSLYAKGMSTRDIVDAFKEMYGADVSPTLISKVTESVLEKVTQWQERPLDEIYPIIYLDGIVLKIRQDKQVLRKTMYVALGINLEGRKECLGLWLSENESSKFWLNVLNDLHARGVKDILIASVDGLTGFPEAINAVYPKTDIQLCIVHMVRNSLKYVGYKERKLVATDLKDIYQSVTEAGALMALERFEQKWDAKFPSISKSWRTHWDNVSTLFLYPESIRKAIYTTNAIESLNSVIRKAVNNRKIFGHDNSAFKIVFLAIESASKKWTMPIRDWNAAMNQFMILHEDRLKGRV
>NZ_AP021888.1|WP_173292027.1|2251242_2252142_+|hypothetical-protein
MHPTICSRASVNLKEQFKSLFSVSSSNITSPYQTSVSIDMLDELSIPSLFALLSHASPSYIDAGQLLVSTRHLASTDESDGRSYNVFTRLSSSERKLLGYYNYDISSCLQIVSFGLLYRYSSNPELFSDYCLVFNYAWDTDFKRSFRQQISNDIVIDESDVKKELTAFANGKRNSHLEHPMLEMFQQQSDRLRREVLALIFTYEPDVFAIALSQSRKDLPDNVNWIDIEAPEEPALAYAKSSVFFFVWTYYEKQIRDAMLSLVDDGIPLHDAIYSRRIVSPDTFEKAIFDQTGFEVKIA
>NZ_AP021888.1|WP_173292028.1|2252533_2255734_-|hypothetical-protein
MAITAAQRLDIIKATVSVFGIAPAGYMTALTSIYEAVGGNLTAFTTALTNTAAYQSASFYPSYLTNAEVATKMAAAFALSDTTTPAGQAAYDYFLANLNAGASAGSLFAAAQQFLDTTTDTAFATAKATLANKAAVAEYYTVTQAATGTDLGVLASVVSGVTSTTDVSTAAAMAAVISTTAGAASGQTFTLTTGADNITGTANNDTFSGLSQATAAAATDTLTAADIIDGGAGIDTLNITTTAANTDVTDGAQITNIEVVNIRAATAGTTSTLDASSIAGLTGVNANAGAGAVTVTNLATGASMTVTGNGTVTNGAITFGYATGTDAVTLNVAGGTKVGTTVSNTGTATTATINSTGAANILGTVDIANATLTSVTINATTNLKADLLSQATDQVGTDGAVTISGAATTVELTAALDNTIKTIDASGLTAGGVKATLGTGTEDYKGGAGVDTITLAAGVKTATFGAGNDVVTTTSNAGLAGTAAGVVNGGEGTDTLVVAHANDVDTSAERAVFTSFETLNNATTGAIAADGFTGVTSLISSGIQGGFTAMNATQAAAITNTAVQAGGTTYALTTATGTSDVLSIETKHATATTAADLAALTVNGFETMNVTVSSGNVDETNAEATVVSFAAATDLTSLNIAGAFAANVILDNTSKAVTVANTLSGTAAMKVEGELIKGSSVTTTANGDTIETALAAIAGVQGEFVSYNAGAGDDAISTSLTAINNTNNALASLKIEGGEGTDTLSFDTADATFADAQFQYVTGVEKVTLTNITSLSVTSGGFFDNNFKASGVTLTTGTTANGATQTIDLSSFTGAATIVATTAGDGASTADNSSITTGSGADTVTLTATSWVGAAGAAGAINVVTGGGNDTISVTTGTLLAVTGTNAVTINAGTGADTITAVHDNAGSGLGNFTFVIADGDSLAASRDKITGFDLGTAAKFADTLDLNGTPTVTANTAGTNGTDSGSIKSHAITSGIITFDDVDTFATALTVNESNLSTVLTYLATNITTAGDTVAFAYDSNSDGTTDATIVFQQGTNDTVVELVGVVATSISATNATTAGLIDLA
>NZ_AP021888.1|WP_173292029.1|2255916_2256879_-|hypothetical-protein
MQSQFDQIELKLLNNPDNRYFQLAYSILMSECESPIAQSKWQANGRSLTSLGFSTNPSRLSNLNAFEITLPEGTLSFLNQSKPKSSVFGGVDISVNLIYNNQYSLAMSVSRQEYAMVAEQESYFIGIDSVINKVDLAGLSVSKQTLFGIEQNTLKLFYKKTLSKKISFGVVLAENSYRNATIFNDNQLNIEVSAFLDNTLKVQAAAISSFPQQIRAGGRYDALEFNLIKGRSVSEGVNAFLGVGLRFQKDSQAYSPLIKNNAVRELVVLKGMALLEKSFKTKFLGDFKSYARVSYLEQKSSLAMFEWHTLDFELGLLKSW
>NZ_AP021888.1|WP_173292030.1|2257065_2258514_-|FecR-domain-containing-protein
MLSFRSLQLCKLSWLGWLKSYLNQKVAKSMVLVSGLLMISAQSLALEGSVNSSNMQVIGQVMLMTGKDAVLIRNNQALPLKMKADILEGDSLQTQQGTFVHLKMKDNARISLRPQSQLEIVCYQVQQQSKGCMKLTLKQGEVRVVDGDAAKLAPETFRLNTPVAAIGVKGTDFVVSSTLQESLVRVLEGAVVASPFGGDCTANGLGVCTTSLSSVLSALDPYALRVTPGVLPLKVPLDNLPDVVAQKSLKQLQALAGQDLEQSSQSSSAASPVTDVAVTDVATILADSPLLVEKFLTKSLQYFKESSSVSSVPVSVSQDIPLVFSYWTNDAKGLNVPIDSAREGRSVTVGDNQTVLWRNQGEYLPMPGVVNYGLKAAEGFLYTQGDAKVVGVLGGALKINFDSRLFQTRLDMLMPGGAFNSQSIESTMARDDGIFALKNQMGVTVNGAISNDGQAVGYILNQQSQDGLLKVQTLWQSNSVVP

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Crispr_ID: NZ_AP021888_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP021888_3

2607749-2607836

Orphan

Consensus_repeat	Method
AGGAAGGCTGAAGCCTTCGCCCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_AP021888_3

>merge|NZ_AP021888|3|2607749-2607836|CRISPRCasFinder
AGGAAGGCTGAAGCCTTCGCCCCATTTATCTTTTTTAGCCTGCTGAGGTTGTGAAAAATTCAATAGGAAGGCTGAAGCCTTCGCCCCA

>NZ_AP021888|3|2|2607749-2607836|CRISPRCasFinder
AGGAAGGCTGAAGCCTTCGCCCCA	TTTATCTTTTTTAGCCTGCTGAGGTTGTGAAAAATTCAAT
AGGAAGGCTGAAGCCTTCGCCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP021888.1\|WP_173292304.1\|2602830_2603352_+\|transposase	unknown	unknown	gnl\|CDD\|376616
NZ_AP021888.1\|WP_173292544.1\|2616206_2617292_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NZ_AP021888.1\|WP_173292305.1\|2603625_2604228_-\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|376738
NZ_AP021888.1\|WP_173292542.1\|2602032_2602272_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226863
NZ_AP021888.1\|WP_173292310.1\|2611585_2613895_-\|MCP-four-helix-bundle-domain-containing-protein	unknown	unknown	gnl\|CDD\|185008
NZ_AP021888.1\|WP_173292313.1\|2615423_2616032_-\|YigZ-family-protein	unknown	unknown	gnl\|CDD\|183205
NZ_AP021888.1\|WP_173292308.1\|2610097_2610976_-\|HDOD-domain-containing-protein	unknown	unknown	gnl\|CDD\|370050
NZ_AP021888.1\|WP_173292298.1\|2593104_2597202_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_AP021888.1\|WP_173292299.1\|2597203_2598181_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270281
NZ_AP021888.1\|WP_173292301.1\|2598599_2601434_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227334
NZ_AP021888.1\|WP_173292303.1\|2602264_2602666_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350302
NZ_AP021888.1\|WP_173292314.1\|2617507_2620507_-\|response-regulator	unknown	unknown	gnl\|CDD\|214599
NZ_AP021888.1\|WP_173292312.1\|2614386_2614956_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292302.1\|2601443_2601920_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292546.1\|2620593_2623740_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_AP021888.1\|WP_173292306.1\|2604640_2607346_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NZ_AP021888.1\|WP_173292300.1\|2598315_2598522_+\|hypothetical-protein	unknown	unknown	unknown
NZ_AP021888.1\|WP_173292307.1\|2608110_2609988_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|185001
NZ_AP021888.1\|WP_173292311.1\|2613987_2614347_-\|response-regulator	unknown	unknown	gnl\|CDD\|381110
NZ_AP021888.1\|WP_173292309.1\|2611019_2611586_-\|purine-binding-chemotaxis-protein-CheW	unknown	unknown	gnl\|CDD\|223905

Protein	Function_ID	Function_description	E-value
NZ_AP021888.1\|WP_173292304.1\|2602830_2603352_+\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	7.08929e-15
NZ_AP021888.1\|WP_173292544.1\|2616206_2617292_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	4.77197e-50
NZ_AP021888.1\|WP_173292305.1\|2603625_2604228_-\|LPP20-family-lipoprotein	gnl\|CDD\|376738	pfam02169, LPP20, LPP20 lipoprotein. This family contains the LPP20 lipoprotein, which is a non-essential class of lipoprotein.	1.89977e-09
NZ_AP021888.1\|WP_173292542.1\|2602032_2602272_+\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|226863	COG4456, VagC, Virulence-associated protein and related proteins [Function unknown].	3.54548e-16
NZ_AP021888.1\|WP_173292310.1\|2611585_2613895_-\|MCP-four-helix-bundle-domain-containing-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	5.82852e-71
NZ_AP021888.1\|WP_173292313.1\|2615423_2616032_-\|YigZ-family-protein	gnl\|CDD\|183205	PRK11568, PRK11568, IMPACT family protein.	3.93529e-60
NZ_AP021888.1\|WP_173292298.1\|2593104_2597202_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	6.82762e-75
NZ_AP021888.1\|WP_173292303.1\|2602264_2602666_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350302	cd18735, PIN_HiVapC1-like, VapC-like PIN domain of Haemophilus influenzae VapC1 and related proteins. Haemophilus influenzae VapC1 has endonucleolytic activity with RNA, it cleaves initiator tRNA between the anticodon stem and loop, but does not cleave mRNA, rRNA or tmRNA, and has no activity on ssDNA or dsDNA. This subfamily belongs to the PIN_VapC4-5_FitB-like subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC TA systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. FitB is a toxin of the FitAB TA system. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	2.2831e-63
NZ_AP021888.1\|WP_173292301.1\|2598599_2601434_+\|EAL-domain-containing-protein	gnl\|CDD\|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	4.82974e-81
NZ_AP021888.1\|WP_173292308.1\|2610097_2610976_-\|HDOD-domain-containing-protein	gnl\|CDD\|370050	pfam08668, HDOD, HDOD domain.	4.16993e-14
NZ_AP021888.1\|WP_173292546.1\|2620593_2623740_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_AP021888.1\|WP_173292299.1\|2597203_2598181_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270281	cd13563, PBP2_SsuA_like_6, Putative substrate binding domain of sulfonate binding protein-like, a member of the type 2 periplasmic binding protein fold. This subfamily includes the periplasmic component of putative ABC-type sulfonate transport system similar to SsuA. These domains are found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.87805e-45
NZ_AP021888.1\|WP_173292306.1\|2604640_2607346_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	9.57088e-92
NZ_AP021888.1\|WP_173292309.1\|2611019_2611586_-\|purine-binding-chemotaxis-protein-CheW	gnl\|CDD\|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	6.7753e-43
NZ_AP021888.1\|WP_173292307.1\|2608110_2609988_-\|PAS-domain-S-box-protein	gnl\|CDD\|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	1.36608e-69
NZ_AP021888.1\|WP_173292311.1\|2613987_2614347_-\|response-regulator	gnl\|CDD\|381110	cd17562, REC_CheY4-like, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY4 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY4 and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	8.2637e-63
NZ_AP021888.1\|WP_173292314.1\|2617507_2620507_-\|response-regulator	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.04727e-57

>NZ_AP021888.1|WP_173292306.1|2604640_2607346_+|response-regulator
MHRLKYKPEFKSQISLIYIVTSIMLGVIFVLAFLAFERFQTVQKTWETQSERTAQINNALAEINRTTGYGGFIHNFKNLVLRRDNARYDSAIQNNIKDLTGAIQRLDNLMHREEDKQAVKQLNDTFDEYIQKYYQVSPMIMAGKNSDEIDAIVKVDDAPALQARELLVKHIAERTAEYAAHAKATYAQAIQYLWINAVIVLLSLLLGAAFLVRTVKQVFAKELEVEDEKEKLALAYQRDKKVQEELKLISQRLLLATKTSKMGVWDFNLTTGDLSWDENMYLIYGVDKNIKDNLIGVWQSAVLPEDLEVSQTLMQYSIATGEDYDQVFRVRKPDGEIRHIQALAKPVFGTFGEAEKMVGINQDITESIRNFNELRTAKEHAEEANKAKDQFLANFSHEIRTPLNAIIGLSEMGAYEAKLSVTQQYHEKIFKSGQHLLHIINDILDFSKIEAGKMKFESRPMNMHQVFDSLKQFFDNMASSKGIAFKIIIANKISPAYFGDQLRLTQVLTNLIGNAIKFTDQGSVTLTVSCQKPNEHFSMVRFCVKDTGVGIDSHSQKVLFQPFEQVDNSHTRKVGGTGLGLAISQRLVQGMGGKEILLNSTPNEGSVFYFELPLAESSVIPTFKPRPKDSLTSIKGQILVAEDNDINQEVVKAKLKQYGLKVTLANDGLEAVEKARTGTYDLILMDIQMPNMDGYEATQAIREFNKKIPIIALTAAARNEDRELAIHAGMNGHLSKPIESDKLEEVLVNWLELKVEHPPETKDVPADALDAAIENTEATNPTNEPMFIDRDLGIKMLDGNESMYDLLLGRLLEQLTAECDPLMAALKALNGNSSEEDWKIAQLQVHTLKGVTCTLAATPLCNLSTEIDALLKTKSRPTPGLLEQYHNTFKATIQALEALTQ
>NZ_AP021888.1|WP_173292305.1|2603625_2604228_-|LPP20-family-lipoprotein
MKKLALISALSATVFLWGCSETPKQEDEAAAATPVFDCVFPNSKEAAPGWICDEPVPGIEVSAVGIAEPSKAGLSYMKDMAATDARGRLAEQMQVQVQKMVKQYLGTTGVADTETVDAAASSTIKTIANQTLTGSKIYKTRTGPDGKLYALVGFDAASTAKIAENAVKTSMKNDQALWQQFQAQKSFDEMAAGIAQQAAQ
>NZ_AP021888.1|WP_173292304.1|2602830_2603352_+|transposase
MRKSLVHFSELESFQFVTFRTQASIEDYQERLHLSPNLSSSQKQTLIDDYCDQSLLGRYLNGDVLEQLMQSVKSLEPDYYHLIAVSIMPNHVHILFQQKQTTTQIMHKLKGSSTLMINKMLKQQGHFWEKSYFDKAIRNQKHFDITYEYIKNNAIKAGLTDAHQRFWGIYEAG
>NZ_AP021888.1|WP_173292303.1|2602264_2602666_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MIKYLLDTNICIYVIKRRPIEVLQKFNEAAGHIAISSITLAELLHGVEKSQHLAKNLKAVEDFCSRLDVLNYDDKAASHYGEIRADLEKKGKPIGVNDLHIAGHARSMGAILVSNNLKEFERVEGLRLQNWID
>NZ_AP021888.1|WP_173292542.1|2602032_2602272_+|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MNATVFENNKTQAVRLPVAVRFPSSVKKVVVRAVGKERVICPLENTWDSFFLNPETAVSDDFLNERAQQTESPREAFDD
>NZ_AP021888.1|WP_173292302.1|2601443_2601920_+|hypothetical-protein
MPTNPTEYETAMLNAFVQKLDKLSYYQNAYQTMNLTGSGQPQLKWFWSWWGFGGGFAFLLYRKAYLEALVAFILGILVNVIPFGGLILMIVMGGTSPYFVVKRYATLKAEIERSHADPDARIQAMQAVGGFHTWVIWVTAIFYGLVLLGILSMLSMIS
>NZ_AP021888.1|WP_173292301.1|2598599_2601434_+|EAL-domain-containing-protein
MTNPALSQFLNHLAPLPSAMVLVDFNTGNLVFLNQAAERLFGYTTEQVVGKSQQILHPPIMNQADKDTFIKHRQQLEKQGQVEGMENIALHADGSHTHVEINVNILEIAHQKLMVGVFTPIEKRVQAMRELRQHKDELQAIFNNSQVGIFNVDQNRIITRVNQRFLTIFGYDLEAEVLGRSVEVIHESHKSYLKFGLAYFSQLPQKNALHIEYPMRKKSGKLIWCRISGKAIHADANSIAEGATWVIDDISDRKATEHALELERNLFTGGPTTILQWQPVEGWPVVYASKNVTQNLGYTQEDLRAPDFRFSELIHDLDAERVGKEVSQYLAEQRDHFEQYYRIKTKSGSYRSFYDYTQVEYNELGEPINIYGYLIDMTAYLNAQEMNQLLLAHSTEGIMGIDSRGHTSFVNPAALKMLGYEQDELIDKANHELIHHSDGDGNHIHAQDCRMSLPLKTGENYHVTDEVLWRKDGSSFAIEYWSTPMLKNSEIIGSVVTFHDISKRLEQENKIKHLAYHDPLTGLPNRRQLMRNLHAEIQDENNLAQRASLMLLDIDHFKEVNDSLGHPIGDELLKGIVGRIQNIIRPADTFARIGGDEFAILIPHDLGGINALKIAERIIETFKTPFKIKNHHIKSNTSIGITLCNSGLKIDNIISQADIALYEAKNQGRGNFVFYELSMIDKVNDDLKLFNGLTQALNKQEFSLHYQLKFDAKNQQIDGAEMLLRWHPKDESLIKFSRPDIFIPMSEKRNYLQTIGLWQLEQLAKDIPLLKAAGLKGRISINLSGCQLSNVHKFERFIEVVLQLNMALTDLEFEITETAYANLSDTIKDALSKLQNQGLSIAIDDFGTGYSSLVALRELHSNILKIDKQFVDDLDTSEDDEAIVSAIIYMAHALGKAVVAEGVETEQQMLKLQTLGCDIYQGYYFARPQSCQDTCRHLQSLTQK
>NZ_AP021888.1|WP_173292300.1|2598315_2598522_+|hypothetical-protein
MLSVLIVGMLLLFAGLGALWFGFFYLRKRPGFEHWNSREANRLMLKTTLIAYFLGVVTIIFMMNQAVA
>NZ_AP021888.1|WP_173292299.1|2597203_2598181_-|ABC-transporter-substrate-binding-protein
MSDCLMLTRRQFTKNLFALSALSSVPLLSSCEKTGALRIGIHPWVGYESLYLAEESGELPNKVKLVKTQGNAENLALLSTGEIDGGTFTVDEVLLARSQGIPLVIVMLFDISAGADQVLTKTGGPIKAGNTVAYEPSAVGTLLFYLALERQGLTPKDVFGVRLAPSYQLNSWLGGELDAAITYEPHASKLKAAGAKEWINSRQFPDTITDTLAVRADRLPQFELTLRELIKTHFKIIEAMRINPDNYLYRIASHQEITYNQAKQGLAGIILPSILRNYELLAERSGFRTRIAEINILMTEEKLIPQADNLENLILTDYLPVPAGA
>NZ_AP021888.1|WP_173292298.1|2593104_2597202_-|EAL-domain-containing-protein
MYLKRLMQIGLLLALMGISSLSVAERTLNLGIYAHLDEASMHQKYGPLVDYLNAALPGIHINYQVLPAKELRESIHKNQFDLLFTNPSLYQIIRYENSLGGAIATVQTLHHGQAVSSLGGVIFTRADAGLKTLKQLEKQTVAVPGFSNTGAYRIPLYELFHQGVNKEAISFITVGNNDDVVRAVLEGVAKAGFVRTGILESWFKQGQLTPADITVLNQKKLGSFPFLLSTDLFPEWPFFALSHVSDKDIKALSVALFNLKASDPAAKAAGIAGFVPALDYLSFETLLRELHLYPFDVKPEFSLKAFWQVYALEIKAALAAAILVLVLLVLSGWLSFKLKKTAQKAKQESERVQSFIEATQSGTWEWQVETGEVCFNYYWAASLGYELTELKPHVETFFELIHPDDLPRVQQALTEHFSGAKNIMDIEVRLRHKDGSWRWMLDRGQVLVWNEQHQPLVMSGTHTDITQSKQQQMALQRKADRDAVFLELPYWLEKHNEAEFLQAMLDRLEDLTQSGASFIHGYEEATDTIHLLSWSRRTLQTYCHMDKMSMHYPLKDAGIWADCVRQKRAIMVNDYESAHSDHKKGFPEGHAQLERFLTVPVFDKSQVVMLLGVANKPEPYNAEDVEDVQLLGNEVYRLLQISRNQQKLQQAANVFKFSQEGIVMTDASVNIVEMNATYLKMCGYRREELLGQNPRILSSGRQDAIFYAQMWKEIFDEGFWKGEIWNRHKSGAVYPQLAHISAVKNAEGHVTHYIGLFSDISTQKNQQAALEKIAHYDALTQLPNRTLLTDRLEQAMARAKRNGKMLAVGFMDLDGFKEVNDTYGHEAGDYLLVALSKRFQKLLRAEDTIARLGGDEFVLVIVDLVRAEQVKGLLQRILEETLVAVHYEGAQLQVSVSIGISFYAPETDSHLTFDMLNDLDADQLIRQADQAMYRAKNLGKNQVVVFQDHFSNVINEGNLSKEVSAALDNHEFCLYYQPKVNLRKGKIDSFEALIRWQHPRKGFLTPQHFLEGITSPEVKIKMSFWVIRSVLKQMLVWQKFSNSSSDFADVLLQKMVQDPRDFSISVFADMRVSVNVDAVTLEHPEFVSHLKVLLDEFPQIHPSFLTLEILESSALQDIKQISSVIMATRALGVNFAIDDFGVGYASLHYLRDLPVHELKVDQTFISTLLEQSQSLSILEAILGMSEAFAHQVIAEGVETPEHCKILQQLGYELVQGYAISRPMPAEAVVEWIETWEPDPSWANNSPLSRAGRSLLIAMIEHRIWVDQLQKWVLEASSKLPELNAVHCRFGEWFSLQSPKLLDKKINRQLLNDIHLQHLEIHAKANQLVEMVRQKDSEKVQTHLSELLVMRDNILAALEAVAIKLP
>NZ_AP021888.1|WP_173292307.1|2608110_2609988_-|PAS-domain-S-box-protein
MFCTSYKNQLNQQSQALAESKAMLEALNKTSAIIEFDLSGHILNANPNFLNTVGYSLSEIQGKHHRIFMLDKDANQPEYAQFWQTLSRGQALSQRFRRKQKNGDVIWLEASYNPVFDASGKPYKVVKFATNITEQVKAEIEAKAQIAAIHKVMAVIEFDSQGNILTANDNFCKTMGYSLAELQGQHHRIFAKPEFAQSSDYQNFWAQLRSGQAFSGTYQRFGKNGREVWLEASYNPIKDCDGKVCKIIKYATDIGSNANSQLLERVIKDASKVILAIQEGDLTASMQVHTDAKNPSMYDKNIVQLVNAIQAMSSKLKSVIGIAVQASVSVSSSSAEVKLSAHQLSGSMQAQAAALENTSTSMRQMNEVIQANTANAQSASQVAQDVQGKSRQGAQVMGQTLDAMNQIQESSRKIADIVTLIDGIAFQTNLLALNAAVEAARAGDHGRGFAVVAGEVRSLAQKSAEAAKDIKKLIDETVERVNQGSRLASQSGEVLQTITEAIGSVTSKVTEIATASLEQAQGIQQVNGSIAQIEQVSQQNAALVEETSAAAESMSEQAQILQEDMAFFKTGQAMPTISRPKVSANVSTKAALPKPVLASKTPQKQPGLVKNPPKIVKKDDEWDDF
>NZ_AP021888.1|WP_173292308.1|2610097_2610976_-|HDOD-domain-containing-protein
MNIAMKEGMDEAKKLIQNLKIQSMPPEIYQLDELMLAEKPNMNQIANLLSKNPEILGEFLSLANKILQKTEDDLILEALAAVNLLGLQEIQRLFISCYLQKNLPVSDVDFKLIKNSTRSGIAAAELSYWVPEIGRTEAYFIAFLQDVGAIYMMRHDPENYAEQFLNLQLSNPVTAYQAELDHYHTAHSFVGSLVARRWHLGDLLCKSLLLHHYDSLEAVQNYDAKVAKMVALIQVSNVLVYRQFSDHYETHEQKQVFDHAVEFLALQPNAIEAASAALKKWGYDDHVHKASH
>NZ_AP021888.1|WP_173292309.1|2611019_2611586_-|purine-binding-chemotaxis-protein-CheW
MEASVSSASTSAGNEASFVASTQAAEQVLTFVLGRETYGLDILRVQEIRGWEPPTQLPQMPHYVKGVINMRGAVIPIVDLRQRFEIGQPTYDDSTVVIITKMRATDKIEGKQIEKTIGMVVDGVSDVESVDMQQLQPAPAFSEAGQVGEQFIKGLANVAEAQSADDKMIIVLNVDALIHQGIFNQLRH
>NZ_AP021888.1|WP_173292310.1|2611585_2613895_-|MCP-four-helix-bundle-domain-containing-protein
MAWFYHLSIRTKLLSLIGLLLVLMGIIGFMGLNNTSKVNDMADEMYQKELLGLSYIKEANIDLLYQSRAVRNFLLAQTDASIDQSQYLDALKKYQDLFDEHIKKAEPLFYTAAAKQKFAELNEKGNQFEAFTNRVIELAQSEKASGAVQEQERQTIKMALIEGRQLADSVDNAMTALTELKEQNAAAASVASTQLYEQSKLMMTAVLLGALLLGLVIGLMVSGRIKNNVEGLVKQMGELVKTQNLSLRMPKRDDDETGDIAEALNGLLETFAKGIDETQSVVEAIAKADYQKRIVGQYQGDLLELKDGVNASAESVSFMMDELSKVMDALHNGKFDIKMDKRVPKGFSKQVEDALSSINQVVIEINVAMQEMNQGDFEGEITVDARGALLSLKNNINGSLKNMAMAISAISEVVEAQAAGDLTKELPSGTFKGQLHDLKNAINYSSAKVREVVQVAIEASQVVSGAAQEVSQGSLDLSQSVQEQAAALEQTSATMNEMNSQVQSSSANAKEATNVAKTVQKKAHDGVGVMRQTITAMTAIEESSHKISDIVSLIDGIAFQTNLLALNAAVEAARAGDHGRGFAVVAGEVRNLAQKSAEAAKDIKVLIDETVQRVGQGSRLATESGDMLNDINTSIESVTKMMDEIAQAAAEQADGVHQVHQAITQIDGVTQQNAALVEETSAASESLSEQARLLQKEMSFFRIGAHSNASYNSQSKAAVKTPALAAPKAAVKPVQKQPGLVKNTPKLAAPAPKALSAKSQGNSDEWGEF
>NZ_AP021888.1|WP_173292311.1|2613987_2614347_-|response-regulator
MKKILTVDDSRSMLQMVSMTLRVANYEVHEAADGAIAFAMAQQQQFDAVITDINMPNMNGIELVKALRGLPDYKFTPVLCLTTESSDDMKGQGKAAGATGWLVKPFSPEKLLGIIERLI
>NZ_AP021888.1|WP_173292312.1|2614386_2614956_-|hypothetical-protein
MQAQEKEPQFELLKLFKYHTEQREDFLNVIEMYFQNLEGVVFSMDQLNLEEDGTKQSKDIYLGLLSFHLNKILILQRSAEKNESDMLGAVGSKFLNSDLNEIRDFEVLRSLMLLGGEMTQTAVQKLSKSLTAVQSYQLYSGELSNQQLIEVFQEIGQEIVGYLRSNIEQMHHHNSHWRTWMAACCNSLK
>NZ_AP021888.1|WP_173292313.1|2615423_2616032_-|YigZ-family-protein
MFLEPVDTVCEEIEIKKSKFISWAKKVLSRQDAMDFVLELRAQYPDARHVCWGYLIGDPNNSTNSGCNDDGEPSGTAGKPILSQINYSNIGNVVVVTVRYFGGIRLGAGGLVRAYRESAQKALQALKTEEYTPLIDVTLLCSFNEENHLRRLVESLSGQITDAQYKTEVALTVKLPEKSKIKLTQSLAGFSVEVIFKDRTTS
>NZ_AP021888.1|WP_173292544.1|2616206_2617292_-|Fic-family-protein
MVNQLTGYIPPNLPLQQDLETKAVLKKAITANTALARLNGVTALIPNQAVLINALVLQEAKDSSEIENIITTHDDLYRSSVDASDLSQAVKEVRHYGEALRKGFDLVSNNKLLLVKDIVQIQSILEKNDAGIRKQGGTTLRNDQTGEVIFTPPQQENDIRNALSNLEQYINNPELDDIDPLIKMAVIHHQFETIHPFYDGNGRTGRILNILYLVLSELLDLPILYLSRFITTHKADYYRLLQSVRKEQTWEEWVLFMLEGIEQTANQTIQLIHQIDEQMQTTASEIQQYSTKLYSKDLLEALFVHPYTKIEFIEHRLSITRQTASKYLKQLEDIGILHSTQVGNSKFFINKRFYELLSQPL
>NZ_AP021888.1|WP_173292314.1|2617507_2620507_-|response-regulator
MRNNQPVTNNEYVIPEGQMLVSKTDLQGTITYANEVFVAASGYELEELVGKPHNLLRHPDVPEQVFADFWGTIQSGRPWNQIVKNRRKNGDFYWVEANATPIIESGKITGYISVRMPATREQIKGAEAAYAAVKAGKVKLRHGVPDSLYARFNPLAHWPPLVTIIPATIIAITNEFLSYFFDIDSEILNLSVIVLTLISAMHVMYYLHRIQEAIEAVDDLTNGHLTGKINTHGANTAGTMNRRLKTMQTRLAAQQNEINVEARFSKRMMSGMDDLKTYIMLSDQNGTIVFMNASLIEFLKPIEAIIQKDVPDFNLKKLTGKNIGCLFRNDMDILMACLDLKEPKTFKFNFYSAEVQLSMTPIFDGNGKSLGVAIEWQDIFQELFVQNSIKTLVSDARNGKLHTRLDASQLSGFYKDLCLDINSLMQNLQSTLSDISILIGGLPAKNLTLKAQRQHQGQYGWTIKSLGAGIESLRTSFCSFNNQAKEVSHSAEHVSESNEMLSSSIKAQADELQKTAVAMNLLTQKVNETTEQAKVSNQLAIQTEAGVQESNRNMQEAITAMAEIAEVSQKITGIVTLIDSIAFQTNLLALNAAVEAARAGEHGRGFAVVAGEVRNLAQKSADAAREINGLIGMTAEKIAQGTEKVQATGTSLESIINQVTDMTANIRHISENAQQQARQIHDVNQSIISLDKSASENSTLVLENASLAEYLGDVAKNMDALVGSFQLGDCETVQRATQDQAESQYLVLVVDDNVSNQKVAVMLLTKMGYHTKVAANGREAITQCQRYNPAAILMDIEMPVMNGIEATKAIRKTGYQKPILAYTGHGADFEKTIMSSGMKDIVHKPVKPEELMSKLIKAGCKPNTNSVEAVKCRREKLVAKSDLAKQFDTMVKAHLGWKSKIRSFIDGADIGVTYESAIDHTACALGKWYYGSQGQALMHLPSMKALGEEHAAMHALIKTIMDAFSIDDYEVLEKGVTDLDAQSDKVVELLGQLMEQTAA
>NZ_AP021888.1|WP_173292546.1|2620593_2623740_-|efflux-RND-transporter-permease-subunit
MNRWNVSAYAVKEQSLTLYFIIVVALAGIYAFLHMGRAEDPSFNINTMVVSATWPGATAAEMQDQVADPLEKRLEEILYFDRVETKARAGRVDLLVTFAENTPMDMTQELYYQVRKRLGDEASRLPKGVIGPVFNDDFEDVFFTLYSLTADNWPQDKLVREADKLQIALRQVQGVKKVSLLGEQAPKLFIDLDTVRISQMGLNLTQVQQAIDAQLAVTSAGFIETQGPRLYIRLKSDQLNLSAHEQNVLRLQNTPLLLGTQQILLKDIAEIKQGFEEPPSYVIRNKGEPALLVGVVMKPKVDGLKLEAALQSFEKAYEQQLPLGLKIEKVTNQADAIHGAVSTFQLKFVTALGVVLVVSLLALGFRAGLIVSLAVPLTLGMTFLFMYLNGLNFDRITLGALIISLGLLVDDAIIAIEMMLVKMEEGMDKAKAAAYAWTVTAAPMLVGTLVTVVGFLPIGLAQSRVGEYAGGIFWVLGITLIASWIVAVTFTPYLGVKLLPNPNPNPKPNLDSKTTSTLKGIKPGQNSAENVHKSVYDSKGYRALRQVITGCLRYKFVVVAITLLLFVLAAVGMGKFVAKQFFPSSDRPELMVDVTLPEGTAIQVTDAVTQRLEALINGHEEVKSLSSYIGQGAPRFFLALNPEMPNSAFAKIIVVTHDKNARDALQSKLQTLINQGAFPEARVRVHPLLFGPPVAWPVTFRVVGPDAQELRRIAEDLRQLIAKQDFAIDPHLQWGQRAPILNVVFNNARLAQLGLTPQAVAQQLQAQLQGVAVSQVRDHIRTLAVILRADQATRTQVAQLNGLMIQTPSGQSLPLEQLGKLEVDFEEPILERRNRELYLSVNSEVIPGVQPPVATALIQAQMQPLIDALPFGYRIDVGGSVEESAKGEFSIQAMMPVMLLVLTLLLMVYLKSFSSLFMVMVTAPLGLIGAVAAMILFNQPFGFVANLGLIGLGGILMRNTLILTGQIDENLKHGLDMSEAVIDATIRRARPVVLTAVAAMLAFIPLTTSTFWGPMAYVLIGGIGVGTFLTLLFLPALYAVWFRVKIVS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

543824 : 556998

Acinetobacter_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173290316.1\|543824_544712_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	1.0e-54	39.5
WP_173290318.1\|544750_545182_-	phosphate-starvation-inducible PsiE family protein	NA	NA	NA	NA
WP_173290319.1\|545363_546068_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_173290321.1\|546175_546859_+	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_173290323.1\|546887_548393_+	anthranilate synthase component I	A0A0B5J984	Pandoravirus	4.6e-39	31.8
WP_173290325.1\|548408_548999_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	6.7e-79	70.3
WP_173290328.1\|549022_550045_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.8e-87	49.7
WP_173290330.1\|550125_550923_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	2.6e-65	52.5
WP_173290332.1\|551175_551682_+	adenosylmethionine decarboxylase	E3SJ34	Synechococcus_phage	7.2e-13	39.4
WP_173290334.1\|551671_552526_+	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_173290336.1\|552518_553724_+	type III PLP-dependent enzyme	A0A060D2X4	Bovine_gammaherpesvirus	2.6e-45	31.5
WP_173290338.1\|553749_554166_+	OsmC family protein	NA	NA	NA	NA
WP_173290340.1\|554223_555510_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	5.5e-17	23.5
WP_173290342.1\|555609_556998_+	ATP-dependent RNA helicase DbpA	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	5.5e-55	31.1

DBSCAN-SWA_2

760783 : 769561

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173290697.1\|760783_761602_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-16	30.7
WP_173290699.1\|761620_762358_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_173290701.1\|762387_763083_+	phosphate regulon transcriptional regulator PhoB	W8CYM9	Bacillus_phage	4.5e-34	35.0
WP_173292372.1\|763226_764522_+	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	1.2e-24	30.0
WP_173290703.1\|764551_766123_-	inorganic phosphate transporter	A0A0P0CDM4	Ostreococcus_lucimarinus_virus	3.6e-39	31.4
WP_173290705.1\|766367_767330_+	phosphate ABC transporter substrate-binding protein PstS family protein	NA	NA	NA	NA
WP_173290707.1\|767471_768383_-	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	7.6e-21	28.0
WP_173290709.1\|768394_769561_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	5.1e-30	29.7

DBSCAN-SWA_3

890292 : 936976

Tupanvirus(18.18%)

transposase,protease,integrase,tRNA

attL 880211:880226|attR 943505:943520

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
880211:880226	attL	NA	NA	NA	NA
WP_173290842.1\|890292_892221_+\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	7.9e-137	38.6
WP_173290843.1\|892299_892788_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.6e-12	39.1
WP_173290844.1\|892993_893191_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_173290845.1\|893202_893559_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_173290846.1\|893694_894693_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.2e-35	37.0
WP_173290847.1\|894748_897133_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_173290848.1\|897150_897438_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	4.5e-12	36.0
WP_173290849.1\|897430_897829_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_173290850.1\|897885_898728_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_173290851.1\|898730_899285_-	hypothetical protein	NA	NA	NA	NA
WP_173290852.1\|899314_900160_-	symmetrical bis(5'-nucleosyl)-tetraphosphatase	NA	NA	NA	NA
WP_173290853.1\|900159_900954_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_173290854.1\|900946_901966_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_173292380.1\|901966_903346_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_173290855.1\|903349_905725_-	LPS-assembly protein LptD	NA	NA	NA	NA
WP_173290856.1\|905781_906828_+	phosphotransferase	NA	NA	NA	NA
WP_173290857.1\|906824_907499_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_173290858.1\|907567_907843_+	hypothetical protein	NA	NA	NA	NA
WP_173290859.1\|907877_908651_+	peroxide stress protein YaaA	NA	NA	NA	NA
WP_173290860.1\|908877_909726_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_173290861.1\|909749_910757_-	lipoyl synthase	NA	NA	NA	NA
WP_173290862.1\|910786_911419_-	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_173290863.1\|911433_911718_-	DUF493 domain-containing protein	NA	NA	NA	NA
WP_173290864.1\|911733_912615_-	D-amino acid aminotransferase	NA	NA	NA	NA
WP_173290865.1\|912623_913817_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	7.7e-66	36.4
WP_173290866.1\|913930_915061_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_173290867.1\|915050_916883_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_173290868.1\|916892_917399_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_173290869.1\|917391_918165_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_173290870.1\|918295_919339_-	rod shape-determining protein	NA	NA	NA	NA
WP_173290871.1\|919596_919884_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_173290872.1\|919891_921346_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_173290873.1\|921281_922790_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_173290874.1\|922855_923257_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_173290875.1\|923428_924325_+\|protease	protease HtpX	NA	NA	NA	NA
WP_173290876.1\|924393_924831_-	SufE family protein	NA	NA	NA	NA
WP_173290877.1\|925079_926072_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_173290878.1\|926145_926985_-	phosphoserine phosphatase SerB	NA	NA	NA	NA
WP_173290879.1\|927000_927405_-	RDD family protein	NA	NA	NA	NA
WP_173290880.1\|927480_928149_+	energy-coupling factor ABC transporter permease	NA	NA	NA	NA
WP_173290881.1\|928228_928558_-	hypothetical protein	NA	NA	NA	NA
WP_173292381.1\|928895_930359_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.3e-93	41.7
WP_173290882.1\|930445_932023_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.8e-17	28.7
WP_173289970.1\|933508_934543_+\|transposase	IS481 family transposase	A0A077SLK2	Escherichia_phage	3.0e-159	76.5
WP_173290883.1\|934628_935198_-\|integrase	site-specific integrase	K4K327	Caulobacter_virus	4.9e-10	29.2
WP_173290884.1\|935783_936071_+\|transposase	transposase	NA	NA	NA	NA
WP_173292382.1\|936046_936613_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	3.8e-15	34.3
WP_173290885.1\|936637_936976_+\|transposase	transposase	Q716C2	Shigella_phage	8.7e-15	42.6
943505:943520	attR	NA	NA	NA	NA

DBSCAN-SWA_4

940134 : 988921

uncultured_Mediterranean_phage(14.29%)

integrase,transposase,tRNA

attL 940595:940610|attR 973075:973090

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173290889.1\|940134_940656_+\|tRNA	tRNA adenosine(34) deaminase TadA	A0A0B5J096	Pandoravirus	8.7e-06	43.9
940595:940610	attL	NA	NA	NA	NA
WP_173290890.1\|940806_941382_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_173292383.1\|941392_943489_+	chemotaxis protein CheA	NA	NA	NA	NA
WP_173290891.1\|943662_944253_+	hypothetical protein	NA	NA	NA	NA
WP_173290892.1\|944488_945379_+	hypothetical protein	NA	NA	NA	NA
WP_173290893.1\|945595_947491_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	4.3e-103	34.3
WP_173290894.1\|947554_948127_-	PilZ domain-containing protein	NA	NA	NA	NA
WP_173290895.1\|948244_948727_-	flagellar protein FlgN	NA	NA	NA	NA
WP_173290896.1\|948747_949059_-	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_173290897.1\|949208_949982_-	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_173290898.1\|950120_951092_+	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	4.4e-27	28.3
WP_173290899.1\|951103_952528_+	hypothetical protein	NA	NA	NA	NA
WP_173290900.1\|952866_953268_+	flagellar basal body rod protein FlgB	NA	NA	NA	NA
WP_173290901.1\|953274_953685_+	flagellar basal body rod protein FlgC	NA	NA	NA	NA
WP_173290902.1\|953697_954390_+	flagellar hook capping protein	NA	NA	NA	NA
WP_173290903.1\|954470_956159_+	flagellar hook protein FlgE	NA	NA	NA	NA
WP_173290904.1\|956509_957250_+	flagellar basal body rod protein FlgF	NA	NA	NA	NA
WP_173290905.1\|957276_958068_+	flagellar basal-body rod protein FlgG	NA	NA	NA	NA
WP_173290906.1\|958093_958819_+	flagellar basal body L-ring protein FlgH	NA	NA	NA	NA
WP_173292384.1\|959097_960192_+	flagellar basal body P-ring protein FlgI	NA	NA	NA	NA
WP_173290907.1\|960216_960690_+	rod-binding protein	NA	NA	NA	NA
WP_173290908.1\|960735_962562_+	flagellar hook-associated protein FlgK	NA	NA	NA	NA
WP_173290909.1\|962587_963643_+	flagellar hook-associated protein FlgL	NA	NA	NA	NA
WP_173290910.1\|963720_964932_+	DUF3393 domain-containing protein	I6ZXX9	Escherichia_phage	7.7e-05	35.6
WP_173290911.1\|964918_965512_-	exonuclease domain-containing protein	NA	NA	NA	NA
WP_173290884.1\|965713_966001_+\|transposase	transposase	NA	NA	NA	NA
WP_173292382.1\|965976_966543_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	3.8e-15	34.3
WP_173290912.1\|966567_966906_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q716C2	Shigella_phage	5.1e-15	42.6
WP_173290913.1\|966996_967995_+	UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	A0A1V0SAI8	Catovirus	3.6e-40	36.1
WP_173290914.1\|967998_969156_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	A0A2K9L0G1	Tupanvirus	9.6e-37	33.4
WP_173290915.1\|969208_970762_+	ATP-binding protein	NA	NA	NA	NA
WP_173290916.1\|970945_971797_+	exo-alpha-sialidase	NA	NA	NA	NA
WP_173290917.1\|971923_972625_+	pseudaminic acid cytidylyltransferase	A0A1B1IVD3	uncultured_Mediterranean_phage	1.8e-06	33.6
WP_173290918.1\|972617_973661_+	putative sugar O-methyltransferase	NA	NA	NA	NA
973075:973090	attR	NA	NA	NA	NA
WP_173290919.1\|973660_974746_+	UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase	NA	NA	NA	NA
WP_173290920.1\|974760_975342_+	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	NA	NA	NA	NA
WP_173290921.1\|975360_975654_+	hypothetical protein	NA	NA	NA	NA
WP_173290922.1\|975650_976355_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_173290923.1\|976354_977701_+	long-chain fatty acid--CoA ligase	NA	NA	NA	NA
WP_173290924.1\|977697_978735_+	pseudaminic acid synthase	NA	NA	NA	NA
WP_173290925.1\|978731_979154_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	6.0e-21	42.0
WP_173290926.1\|979150_980629_+	CDP-glycerol glycerophosphotransferase family protein	NA	NA	NA	NA
WP_173290927.1\|980625_981480_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	7.9e-105	65.6
WP_173290928.1\|981493_981895_+	WxcM-like domain-containing protein	NA	NA	NA	NA
WP_173290929.1\|981887_982466_+	N-acetyltransferase	NA	NA	NA	NA
WP_173290930.1\|982502_983027_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_173290931.1\|983043_983298_+	hypothetical protein	NA	NA	NA	NA
WP_173290932.1\|983294_984857_+	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	4.1e-43	31.7
WP_173290933.1\|985024_985291_-\|transposase	transposase	NA	NA	NA	NA
WP_173290934.1\|985369_986950_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_173290935.1\|987100_987454_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.7e-08	32.1
WP_173290936.1\|987718_988921_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	8.1e-47	46.6

DBSCAN-SWA_5

1187047 : 1198829

Mycobacterium_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173291126.1\|1187047_1189606_+	DNA translocase FtsK 4TM domain-containing protein	G1FGP1	Mycobacterium_phage	5.0e-86	47.8
WP_173291127.1\|1189651_1190248_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_173291128.1\|1190252_1191593_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	3.1e-79	39.5
WP_173291129.1\|1191598_1191997_+	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_173291130.1\|1192038_1193331_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.9e-89	41.5
WP_173291131.1\|1193334_1193664_-	MGMT family protein	NA	NA	NA	NA
WP_173291132.1\|1194021_1194513_+	CinA family protein	B5TK85	Pseudomonas_phage	5.1e-32	47.7
WP_173291133.1\|1194684_1195722_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.1e-120	65.3
WP_173291134.1\|1195718_1196183_+	regulatory protein RecX	NA	NA	NA	NA
WP_173291135.1\|1196237_1198829_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.6e-84	40.8

DBSCAN-SWA_6

2259448 : 2270438

Enterobacteria_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173292032.1\|2259448_2261197_+	adenylate/guanylate cyclase domain-containing protein	A0A2H4N7Z5	Lake_Baikal_phage	3.1e-39	25.3
WP_173292033.1\|2261282_2262095_+	ABC transporter permease	NA	NA	NA	NA
WP_173292034.1\|2262084_2263335_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.5e-15	27.5
WP_173292035.1\|2263331_2264228_+	hypothetical protein	NA	NA	NA	NA
WP_173292036.1\|2264176_2266969_+	glycosyltransferase	A0A0E3HGK7	Synechococcus_phage	6.5e-07	28.7
WP_173292037.1\|2267015_2267897_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	7.4e-106	63.1
WP_173292038.1\|2267897_2268473_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.4e-41	50.0
WP_173292039.1\|2268465_2269338_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	3.7e-41	36.3
WP_173292040.1\|2269334_2270438_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.7e-96	52.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_AP021888

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection