CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP045454	Sulfurospirillum sp. ACSTCE plasmid pSDIE1, complete sequence	0 crisprs	WYL	0	0	0	0
NZ_CP045453	Sulfurospirillum sp. ACSTCE chromosome, complete genome	3 crisprs	cas3,DEDDh,cas2,cas1,WYL,csx20,csx1,csm3gr7,csx19,csx10gr5,cas10,cas6,cas4,csa3	0	9	2	0

1. NZ_CP045453

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP045453_1

• CRISPR_ID: NZ_CP045453_1
• CRISPR_location: 579823-580618
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 11 spacers
• Cas_protein_info: cas2,cas1,WYL,csx20

Consensus repeat of NZ_CP045453_1

Consensus_repeat	Method
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CRISPRCasFinder
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CRT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	PILER-CR

spacers of NZ_CP045453_1

>1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT
CAAATCAAAAAGTAGAAAAAGCTATGGTTTATCC
>1.2|579927|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
AATCTGCTGATGTTCTTTTTGAAGAACAAGAAAT
>1.3|579996|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
CAGAATTTATGGGTTACAGTAACCACAATACTAT
>1.4|580065|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
TGGTGATGCTTGGGATTGCACGCTTGATGAGAT
>1.5|580133|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
TCATTCAGAAAACTTAAAAGATTCTGATGGTTGG
>1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
TAAAATTTATTAAAAGGAAATAAAATGATTAAA
>1.7|580270|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
TCATGAACCTTTTCCTAAGCTAAAAATTCTTCTA
>1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
AAAGTAAATGTAAAAGAAGATGGTAGAAAATCTCA
>1.9|580409|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
CGAAAATGCGTCTAGTTATTTTAGCTGTTTTGAC
>1.10|580478|37|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
ATCATTAAATTATTAAAAGGAGTTCCAATGTTATCTT
>1.11|580550|34|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR
AGAAACATTACAATGGTTTATTACAAATCAATCA

CRISPR arrays and Neighbor proteins around NZ_CP045453_1

CRISPR arrays

The CRISPR arrays of NZ_CP045453_1

>merge|NZ_CP045453|1|579823-580618|CRISPRCasFinder,CRT,PILER-CR
AAGCAAATCCCCTTATAATCGGGTCAGTATGTAATCAAATCAAAAAGTAGAAAAAGCTATGGTTTATCCGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATAATCTGCTGATGTTCTTTTTGAAGAACAAGAAATGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCAGAATTTATGGGTTACAGTAACCACAATACTATGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTGGTGATGCTTGGGATTGCACGCTTGATGAGATGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTCATTCAGAAAACTTAAAAGATTCTGATGGTTGGGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTAAAATTTATTAAAAGGAAATAAAATGATTAAAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTCATGAACCTTTTCCTAAGCTAAAAATTCTTCTAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATAAAGTAAATGTAAAAGAAGATGGTAGAAAATCTCAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCGAAAATGCGTCTAGTTATTTTAGCTGTTTTGACGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATATCATTAAATTATTAAAAGGAGTTCCAATGTTATCTTGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATAGAAACATTACAATGGTTTATTACAAATCAATCAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|1|1|579823-580618|CRISPRCasFinder
AAGCAAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAATCAAAAAGTAGAAAAAGCTATGGTTTATCC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AATCTGCTGATGTTCTTTTTGAAGAACAAGAAAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAGAATTTATGGGTTACAGTAACCACAATACTAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGTGATGCTTGGGATTGCACGCTTGATGAGAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATTCAGAAAACTTAAAAGATTCTGATGGTTGG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TAAAATTTATTAAAAGGAAATAAAATGATTAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATGAACCTTTTCCTAAGCTAAAAATTCTTCTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAGTAAATGTAAAAGAAGATGGTAGAAAATCTCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CGAAAATGCGTCTAGTTATTTTAGCTGTTTTGAC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATCATTAAATTATTAAAAGGAGTTCCAATGTTATCTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AGAAACATTACAATGGTTTATTACAAATCAATCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|1|1|579823-580618|CRT
AAGCAAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAATCAAAAAGTAGAAAAAGCTATGGTTTATCC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AATCTGCTGATGTTCTTTTTGAAGAACAAGAAAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAGAATTTATGGGTTACAGTAACCACAATACTAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGTGATGCTTGGGATTGCACGCTTGATGAGAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATTCAGAAAACTTAAAAGATTCTGATGGTTGG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TAAAATTTATTAAAAGGAAATAAAATGATTAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATGAACCTTTTCCTAAGCTAAAAATTCTTCTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAGTAAATGTAAAAGAAGATGGTAGAAAATCTCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CGAAAATGCGTCTAGTTATTTTAGCTGTTTTGAC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATCATTAAATTATTAAAAGGAGTTCCAATGTTATCTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AGAAACATTACAATGGTTTATTACAAATCAATCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|1|1|579892-580618|PILER-CR
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AATCTGCTGATGTTCTTTTTGAAGAACAAGAAAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAGAATTTATGGGTTACAGTAACCACAATACTAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGTGATGCTTGGGATTGCACGCTTGATGAGAT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATTCAGAAAACTTAAAAGATTCTGATGGTTGG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TAAAATTTATTAAAAGGAAATAAAATGATTAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TCATGAACCTTTTCCTAAGCTAAAAATTCTTCTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAGTAAATGTAAAAGAAGATGGTAGAAAATCTCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CGAAAATGCGTCTAGTTATTTTAGCTGTTTTGAC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATCATTAAATTATTAAAAGGAGTTCCAATGTTATCTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AGAAACATTACAATGGTTTATTACAAATCAATCA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045453.1|WP_167750840.1|580805_581072_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|378256
NZ_CP045453.1|WP_167751024.1|582210_583257_+|IS21-family-transposase	unknown	unknown	gnl|CDD|226950
NZ_CP045453.1|WP_167749321.1|584278_584548_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749310.1|568834_569725_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_CP045453.1|WP_025344704.1|583247_584066_+|ATP-binding-protein	unknown	unknown	gnl|CDD|181681
NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NZ_CP045453.1|WP_167749322.1|584537_584789_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749314.1|577951_578176_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP045453.1|WP_167749312.1|575986_577177_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|379080
NZ_CP045453.1|WP_167749320.1|584090_584282_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749308.1|567574_568453_+|nucleoside-recognition-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749318.1|581292_582027_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl|CDD|376633
NZ_CP045453.1|WP_167749313.1|577173_577743_-|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|235552
NZ_CP045453.1|WP_167749323.1|585121_586126_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_CP045453.1|WP_167749311.1|575302_575974_-|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP045453.1|WP_167750838.1|566663_566783_-|transposase	unknown	unknown	gnl|CDD|226950
NZ_CP045453.1|WP_167750839.1|566820_567222_-|transposase	unknown	unknown	gnl|CDD|226950
NZ_CP045453.1|WP_167749309.1|568445_568838_-|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl|CDD|239249
NZ_CP045453.1|WP_167749315.1|578905_579400_-|porin-family-protein	unknown	unknown	gnl|CDD|379226
NZ_CP045453.1|WP_167749317.1|581068_581284_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	8.9e-34	111.2	0.0
NZ_CP045453.1|WP_167750840.1|580805_581072_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	3.9e-20	66.7	0.3
NZ_CP045453.1|WP_167749318.1|581292_582027_-|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	6.9e-45	148.1	0.5
NZ_CP045453.1|WP_167749323.1|585121_586126_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2.2e-23	77.9	1.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045453.1|WP_167750840.1|580805_581072_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	1.07442e-15
NZ_CP045453.1|WP_167751024.1|582210_583257_+|IS21-family-transposase	gnl|CDD|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.83417e-47
NZ_CP045453.1|WP_167749310.1|568834_569725_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	1.69704e-09
NZ_CP045453.1|WP_025344704.1|583247_584066_+|ATP-binding-protein	gnl|CDD|181681	PRK09183, PRK09183, transposase/IS protein; Provisional.	2.49542e-118
NZ_CP045453.1|WP_167749314.1|577951_578176_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00844158
NZ_CP045453.1|WP_167749312.1|575986_577177_-|glycosyltransferase-family-39-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	2.51989e-07
NZ_CP045453.1|WP_167750839.1|566820_567222_-|transposase	gnl|CDD|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.69193e-06
NZ_CP045453.1|WP_167749318.1|581292_582027_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.08963e-44
NZ_CP045453.1|WP_167749313.1|577173_577743_-|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	3.75225e-120
NZ_CP045453.1|WP_167749323.1|585121_586126_-|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.26623e-15
NZ_CP045453.1|WP_167749311.1|575302_575974_-|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	1.55215e-06
NZ_CP045453.1|WP_167750838.1|566663_566783_-|transposase	gnl|CDD|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.77397e-05
NZ_CP045453.1|WP_167749309.1|568445_568838_-|thioredoxin-fold-domain-containing-protein	gnl|CDD|239249	cd02951, SoxW, SoxW family; SoxW is a bacterial periplasmic TRX, containing a redox active CXXC motif, encoded by a genetic locus (sox operon) involved in thiosulfate oxidation. Sulfur bacteria oxidize sulfur compounds to provide reducing equivalents for carbon dioxide fixation during autotrophic growth and the respiratory electron transport chain. It is unclear what the role of SoxW is, since it has been found to be dispensable in the oxidation of thiosulfate to sulfate. SoxW is specifically kept in the reduced state by SoxV, which is essential in thiosulfate oxidation.	2.31613e-08
NZ_CP045453.1|WP_167749315.1|578905_579400_-|porin-family-protein	gnl|CDD|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.86934e-05

Protein sequences

>NZ_CP045453.1|WP_167749315.1|578905_579400_-|porin-family-protein
MTFIQRFLVGGVAIATFSSPIFAEDFYYDLHVGLSHLSINDGGDGANYTIGYGVNRIFDNKVFFGVSFDLETATISDTHIYGLNGDLKLGYNIWDKLNVYAIGGYKLQDLDGTSGYGLGYGAGMEYPITQHIITAIEYKTYHMSRSDYKDYDFDTIGLNLKYRF
>NZ_CP045453.1|WP_167749314.1|577951_578176_-|helix-turn-helix-domain-containing-protein
MDVELLVQKLLEKYGYMLTREEVAEVLNISISTVDRKRKQYPKLFPPFKKIGTGNRAPVKFPVHGVAQYLVQIQ
>NZ_CP045453.1|WP_167749313.1|577173_577743_-|aminodeoxychorismate/anthranilate-synthase-component-II
MVLMIDNYDSFTYNIVQYCLELGADLKVIRNDELSVEEIEALHPEKIIISPGPATPNEAGVSLEVIKYFGGKIPILGICLGHQAIGQAFGGKVVRAKRMMHGKTSITKQLHNSCLFDGLPETFTTTRYHSLTVEQEGLPDVVVPTAYSTDDHEIMALQIKDKQIYGVQFHPESILSEHGHAILNNFLKL
>NZ_CP045453.1|WP_167749312.1|575986_577177_-|glycosyltransferase-family-39-protein
MRERLFLLLILVISSALLTYGAQSISISYDEAYTFFNGNDLVHYLAVYSTQLLGQNDFALRLPFILLHLTSIILLYKIGKLFLKKRIDRIVSVAIYAFLPGVNGVALLVNSGIVVIFFSLLFTYLYLKEWKVASHIVLIICLFVDNSFAIFYIALFVYALMKRKTDLLIVTLILFSASMYLYGFDTGGKPRGYFIDTLGVYAIVFSPLLFLYFVYAMYRILIKEEKNLLWYISFFSLVVSLLLSLRQKLLLEDFAPFVVLSVPLMVKVFFNSYRVRLPAFRKLHTFFFILVLITLFINTMLSFFNKPLYAFMNEPSKHFAINYNIARELANELKARDIHKVITKDDKMALRLKFYNIERGGAYKLMNQKEIEEGFEQIDIAYYGKTVRTFYLYRIN
>NZ_CP045453.1|WP_167749311.1|575302_575974_-|type-II-secretion-system-protein
MKKAFTMLELVFVIVVVGILSYFVSTGFQRNPLREAADQLVSHIRYTQHLAMMDDKFSLTDASWALGRWQLYFSNNTGSDDQWAYTIFSDWKAGHTGNPDMGEVAVNPLNSSQYLTGGTSGTNIIHYSDQSATKELNIGHKYGIKDITFSGGCRSNVKYIHFDYLGRPMNSLSTNPYELPATGWHKLLTTQCKITLCDKDCTDGSAQKVSIAIEAETGYTHIL
>NZ_CP045453.1|WP_167749310.1|568834_569725_-|DMT-family-transporter
MKKNQSKAYFFAISAVLLWSTVASAFKLSLAYFDALNLLLYASFFSLCVFSCAMGYQRKFYILFLYSKKTYFKLALLGLINPFIYYLVLFHAYELLPAQEAQPINYTWALTLTYLSVFILKQKISVYDFLAGLICYFGVLIISTHGDLWGFSFYSLTGVFLALFSTVLWSLYWIYNTKLHVDPLVGLFINFLFGVPAILFYALITSHPLVFNIHGFLGSAYVGIFEMGITFILWLQAMKLSTNTAKIANLIFISPFLSLVFISIFVGEVILFSTYIGLIFIIIGLLLQQRVKKVDR
>NZ_CP045453.1|WP_167749309.1|568445_568838_-|thioredoxin-fold-domain-containing-protein
MKKWICVLIIFLLGTLSLHADFLEAERKKALNEKKLILLSVTKEFCPYCIKMEKDVFENALYRNQIEKKYLHVTINRENPELPQALHVKYFPTNLILSPKDLKIIDDFAGYIEPVSFIELLDEVYEQEFK
>NZ_CP045453.1|WP_167749308.1|567574_568453_+|nucleoside-recognition-protein
MSFSLQRSLQTSLKSSWTILKLIVPIYILADILFYYNLLSYITFIFKPLVALLGLPQETALSIVSGLFLNLYAAIAFAAPLGLSPKEWTVLAVFLGIAHALIVETEIMKRLGISRVYSILLRLCAGLLVGGLTSKLPQSWFSNELSQEAMVPSHPLYHSLSDLLQNSLYESLSLSLKVILLVTTLIFVLDFIKSLHMIEKHSQKVNSGFSILVGVILGITYGAGILIAEYEKGILQKREILFIGTYLMICHAIIEDTLLFVIFGANLWIMVGLRLTFATLIAYLVLKYTKIT
>NZ_CP045453.1|WP_167750839.1|566820_567222_-|transposase
MLKKGEIKMIKKFLAEGFSKSAIARKLGISRETVRRYANLPDDYIPHINRPPVINSVDPYLPHIAKMLETAEQQKSEIPLTVIYEEIKKLGYDGSLRWLQQVILRYELRARAKLDEPIIRFETNKPSRCKLTG
>NZ_CP045453.1|WP_167750838.1|566663_566783_-|transposase
MGYSRASYVEYVNNEKIETLIGCHMNAFAYLVVFQKSVY
>NZ_CP045453.1|WP_167750840.1|580805_581072_-|CRISPR-associated-endonuclease-Cas2
MKNYLLCYDISDKKRLAKLAKLLEKEAFRIQNSIFLLLEPTSHEVDILVQKIEQCIDKAHDDVRLYTIKSNGFHLGSATNLDEPFLLI
>NZ_CP045453.1|WP_167749317.1|581068_581284_-|hypothetical-protein
MLQVNLKGSYIEVSDGVLSQIYGIAQLRSLYLHKEIDLNIATAYELSKYLDIFFINARGMILARYERIQTV
>NZ_CP045453.1|WP_167749318.1|581292_582027_-|CRISPR-associated-endonuclease-Cas1
MTANANVPILYLTKDSKQFALTLPAMAKNGELKALQYANLSNNLSIAKKLLFDKFTTHKASLEHFDITISIDETLTHLALAQSIEEVMGIEGAFAKRYFAHYFSLFEKSLTKGFRSKNPPLDPINAMLSYIYTLSYYAITAKLYMRGFDPSLSYLHTPLRSHFALSSDLLEPLRASINCFVAELFLKQILHAEDFTCKNGVYLKYDTRRQLWTHLKPFMNSLNPQINRQIVMLKKNLEKNDALL
>NZ_CP045453.1|WP_167751024.1|582210_583257_+|IS21-family-transposase
MARKLGISRETVRRYANLPDDYIPHINRPPVINSVDPYLPHIAKMLETAEQQKSEIPLTVIYEEIKKLGYDGSLRWLQQVILRYELRARAKLDEPIIRFETKPAQQMQVDWVEFPKDNLSAFVATMGYSRASYVEYVNNEKIETLIGCHMNAFAYFGGVPKECLYDNMKTVILSRNDYGKGDHRFNPLFADFAKHCGFSIKVCKPYRAKTKGKVERFNHYLRYNFHNGLRVRLSMKHYTLTLDNANAEVLKWLDNTANKRIHQTTLQMPFELLAQEQLQLLPVPKAYQGIHPKALIESVAKKYSPINSHKDLEKLYIPNRDIQCYDEFIPMVANIILPVGFYGGALWS
>NZ_CP045453.1|WP_025344704.1|583247_584066_+|ATP-binding-protein
MELDTSIDELCKELKLSIIGEKYHDIASMAAKENWQYTQFLEEVLRVEVDNRLGRSKNMLTKLAGFPVIKTLEQFDYTFSVGVNRKQIEELSSLIFVKKYENIILLGESGVGKTHLAIALALKAVQHRYKVRFTTISELLSNANRAKKEKKYDSFLKSIASPSVLVIDEIGYFNMSKEEANHFFQIISKRYEKSSTIFTSNLVFSKWVQVFAGDKIVTTAILDRVLHHSHIINIQGDSYRLKEKKQTGVLHSEIYKFEAKSSNIEGQNQEVV
>NZ_CP045453.1|WP_167749320.1|584090_584282_-|hypothetical-protein
MNTIIIDKDKTEVTYKASKLYTAGQSIPIKLVDMLVITDSVCIDTKSIIQIANVKRSAELVSL
>NZ_CP045453.1|WP_167749321.1|584278_584548_-|hypothetical-protein
MMHNYLLCYDIFNGKRLYKIRKISYPFALGGQKSALEMPLSRKEAKVLLTTLSPHSAPEDKINLIEIEEHPLYIGKSIDVIFEEGMIIL
>NZ_CP045453.1|WP_167749322.1|584537_584789_-|hypothetical-protein
MRQWINFSLVHLTYKIKLYYALHKVFYTLLVLMIYQLLVQESILTLKNGIAICVTLILSMLCEHYYKRYLAQYYEARAQNNDA
>NZ_CP045453.1|WP_167749323.1|585121_586126_-|WYL-domain-containing-protein
MKSTTTEKKIIHIFTLMQKLYEGEELYPQNERILDELGVNERTLRRYLEDIHRLYGDILVSEKKQKYLHGKKVSVYRVPNKEQDISKTLRFFLEESNELSWILTLINENNPRFLKQLSLSEKEAIEQAIAQDKEVFLFKSNPFENLQDEHERLFSQLKIAVKHHEYRTIIYRYDNEETVESVKCLKLIFTNNNWYLAIETANEELRLLRIAFIKEVRYSAKTTYQKHVLAKYRYYFESMQNAMSLQGVALKTAVLKASPSIRRYFLKEMKPFFASQKFIEAPSDGSVIFSVDYTQPIEILPFVKQWLPELEILEPKELRILYKTELQKALAQQG
>NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein
MIKKLFVLMNHEMLPSQISQAHEVLGIEKIISLNDTNWSSFDPDVSSIITALASYKSRLLKDASRGDYLLVQGDFGATYHMVCFAKKLGLTPLYATTKRVATQKMVDGSVVTQREFLHVRFREYEDA

Crispr_ID: NZ_CP045453_2

• CRISPR_ID: NZ_CP045453_2
• CRISPR_location: 596915-597428
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas6,cas10,csm3gr7,csx10gr5,csx19,csx1,csx20

Consensus repeat of NZ_CP045453_2

Consensus_repeat	Method
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CRT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	PILER-CR
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATT	CRISPRCasFinder

spacers of NZ_CP045453_2

>2.1|596950|32|NZ_CP045453|CRT
GTAACAGAAGTTGAGCATACAACTGCATATTA
>2.2|597017|35|NZ_CP045453|CRT,PILER-CR
TGGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTA
>2.3|597087|34|NZ_CP045453|CRT,PILER-CR
TTATCAAGGAGAATAAATGATTGTTTCATTTATG
>2.4|597156|34|NZ_CP045453|CRT,PILER-CR
TGGATCAGCAGCAGAATAAAACAATCTTTTTAAG
>2.5|597225|34|NZ_CP045453|CRT,PILER-CR
CTGAAGCGGTAATGGAGAATTTGGAAGGTCTCTC
>2.6|597294|33|NZ_CP045453|CRT,PILER-CR
CAAAAGACGCAAGATCTGCAGAAATTTTAAAAA
>2.7|597362|31|NZ_CP045453|CRT,PILER-CR
CAAAATGCTATCGTACAACGATCCAATTGAA
>2.8|597018|34|NZ_CP045453|CRISPRCasFinder
GGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTA
>2.9|597088|33|NZ_CP045453|CRISPRCasFinder
TATCAAGGAGAATAAATGATTGTTTCATTTATG
>2.10|597157|33|NZ_CP045453|CRISPRCasFinder
GGATCAGCAGCAGAATAAAACAATCTTTTTAAG
>2.11|597226|33|NZ_CP045453|CRISPRCasFinder
TGAAGCGGTAATGGAGAATTTGGAAGGTCTCTC
>2.12|597295|32|NZ_CP045453|CRISPRCasFinder
AAAAGACGCAAGATCTGCAGAAATTTTAAAAA
>2.13|597363|30|NZ_CP045453|CRISPRCasFinder
AAAATGCTATCGTACAACGATCCAATTGAA

CRISPR arrays and Neighbor proteins around NZ_CP045453_2

CRISPR arrays

The CRISPR arrays of NZ_CP045453_2

>merge|NZ_CP045453|2|596915-597428|CRT,PILER-CR,CRISPRCasFinder
AGCAATGATGATGTTAAATCGGGTCAATATGTAATGTAACAGAAGTTGAGCATACAACTGCATATTAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTGGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTTATCAAGGAGAATAAATGATTGTTTCATTTATGGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTGGATCAGCAGCAGAATAAAACAATCTTTTTAAGGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCTGAAGCGGTAATGGAGAATTTGGAAGGTCTCTCGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCAAAAGACGCAAGATCTGCAGAAATTTTAAAAAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCAAAATGCTATCGTACAACGATCCAATTGAAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATA

>NZ_CP045453|2|2|596915-597427|CRT
AGCAATGATGATGTTAAATCGGGTCAATATGTAAT	GTAACAGAAGTTGAGCATACAACTGCATATTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TTATCAAGGAGAATAAATGATTGTTTCATTTATG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGATCAGCAGCAGAATAAAACAATCTTTTTAAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CTGAAGCGGTAATGGAGAATTTGGAAGGTCTCTC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAAGACGCAAGATCTGCAGAAATTTTAAAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAATGCTATCGTACAACGATCCAATTGAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|2|2|596982-597427|PILER-CR
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TTATCAAGGAGAATAAATGATTGTTTCATTTATG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TGGATCAGCAGCAGAATAAAACAATCTTTTTAAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CTGAAGCGGTAATGGAGAATTTGGAAGGTCTCTC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAAGACGCAAGATCTGCAGAAATTTTAAAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAATGCTATCGTACAACGATCCAATTGAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|2|2|596982-597428|CRISPRCasFinder
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATT	GGTTTTTTCTATGCCAATCTCTCTTCTTCTGGTA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATT	TATCAAGGAGAATAAATGATTGTTTCATTTATG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATT	GGATCAGCAGCAGAATAAAACAATCTTTTTAAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATC	TGAAGCGGTAATGGAGAATTTGGAAGGTCTCTC
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATC	AAAAGACGCAAGATCTGCAGAAATTTTAAAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATC	AAAATGCTATCGTACAACGATCCAATTGAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045453.1|WP_167749335.1|599440_599749_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749330.1|592591_593977_-|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NZ_CP045453.1|WP_167749338.1|601871_602420_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749336.1|599761_600016_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749341.1|603507_603948_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749332.1|594497_595889_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810
NZ_CP045453.1|WP_167749331.1|593973_594501_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NZ_CP045453.1|WP_167749329.1|591345_592602_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NZ_CP045453.1|WP_167749326.1|588123_588906_-|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	gnl|CDD|378236
NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407
NZ_CP045453.1|WP_167750842.1|598497_599430_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293818
NZ_CP045453.1|WP_167750841.1|586578_588108_-|CRISPR-associated-DxTHG-motif-protein	csx1	cd09732_csx1_CAS-III	gnl|CDD|378186
NZ_CP045453.1|WP_167749327.1|588902_590966_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl|CDD|187890
NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NZ_CP045453.1|WP_167749340.1|603145_603511_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP045453.1|WP_167749328.1|590962_591349_-|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0121_csx19_CAS-III-D	gnl|CDD|275216
NZ_CP045453.1|WP_167749339.1|602441_603098_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP045453.1|WP_167749326.1|588123_588906_-|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	2.6e-11	37.7	0.1
NZ_CP045453.1|WP_167749327.1|588902_590966_-|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	4e-92	304.9	19.9
NZ_CP045453.1|WP_167749330.1|592591_593977_-|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	2.7e-63	208.7	0.8
NZ_CP045453.1|WP_167750841.1|586578_588108_-|CRISPR-associated-DxTHG-motif-protein	csx1	cd09732_csx1_CAS-III	1.5e-15	52.3	1.7
NZ_CP045453.1|WP_167749332.1|594497_595889_-|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	4.4e-74	244.6	4.3
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.3e-52	173.8	0.5
NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	8.9e-34	111.2	0.0
NZ_CP045453.1|WP_167749328.1|590962_591349_-|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0121_csx19_CAS-III-D	3.3e-36	119.2	1.3
NZ_CP045453.1|WP_167749331.1|593973_594501_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.4e-14	49.7	0.0
NZ_CP045453.1|WP_167749329.1|591345_592602_-|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	2.5e-29	97.7	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045453.1|WP_167749326.1|588123_588906_-|hypothetical-protein	gnl|CDD|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	1.34417e-05
NZ_CP045453.1|WP_167749327.1|588902_590966_-|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	8.85889e-83
NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase	gnl|CDD|293818	cd07732, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Includes functionally uncharacterized Enterococcus faecalis EF2904. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	4.13275e-69
NZ_CP045453.1|WP_167750841.1|586578_588108_-|CRISPR-associated-DxTHG-motif-protein	gnl|CDD|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.43381e-09
NZ_CP045453.1|WP_167749328.1|590962_591349_-|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	3.30856e-13
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	1.11365e-08
NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	1.13984e-59
NZ_CP045453.1|WP_167749332.1|594497_595889_-|hypothetical-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	6.73193e-08
NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.72834e-06
NZ_CP045453.1|WP_167749331.1|593973_594501_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.22404e-10
NZ_CP045453.1|WP_167749329.1|591345_592602_-|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	4.65356e-15

Protein sequences

>NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLRFIKIDITFSSSFTTSLDFLGSTLRGAFGVALKAVSCLNKTQECQGCFATQNCLYYDFFEIKNRAHAYRFSKPLHENNYNFSLYLFEAACEKLPYVLSALHTMFGRIGVGWNRHLIPIERIVCNGVVVSSGKNFDLSQIVVDVFETKEYFPDITLHFLTPLRIKSNNALLHTTPTLEQILSSIFNRHNELKGIPLAKLPFTPRYKELRTHLRFQELSRYSNRQESTMHLGGMMGTIDYEDVDEHSYALLKLGELLGVGKQTVFGLGEIKVGHQ
>NZ_CP045453.1|WP_167749332.1|594497_595889_-|hypothetical-protein
MAKYLYGASIQGIQEFIFKTNQLQEIIGASEIVRSLEGEFTAFANVADENILLNAAGNIKALFDDEENLRNVVKNFPKKIMQKAYGITLSQAVVDMTKAEYDTYEKAINALEKKLKTQRNKPSIPLDISINLMELAPKTARPVAKIEKKGNDEIRMDVSTAQKYQANPTNKGQLSDLKNSKGKIAIIHADGNGLGALIPTLSNIPVFSKGLDKATHEAYEEAKKVIQSGKIRKIILGGDDMSVICDANDALAFTRTFLEKFETLTYMHTGHKLTACAGIAFCNEKYPFHYAVSLAEALCGATKKHAKNIDKKLAPSSLMFHNIQSSNFQSWEKFIEDELTIRNDHDVIRCDFGPYYVAHVGQPSIEDLIDVVKVYQQEGSPISRLREWLGELSKSHHYAKDLLDRINENSAQNDKKALDTLNLKLKKVHPALGTQTMIIPKDGFDKTLIYDVLQILSVTEAKA
>NZ_CP045453.1|WP_167749331.1|593973_594501_-|CRISPR-associated-protein
MTLRYQLKFYDYWHIGSGLSAGARLDSTVIKDQNDLPYVAGKIIKGLSREMAETLDDADFVNTCFGNNGIEMGKCYFSNAQLLETTAKHICSLNLQSNLYDIIASTKIDETNGVAEDNSLREIEVVVPLELCGEIRDLPENYKEAMTRSLKMIKRMGLNRNRGLGRCEFFVEENQ
>NZ_CP045453.1|WP_167749330.1|592591_593977_-|hypothetical-protein
MKELVFHVEFLSDIVLPATSNTEGKIDHLDFIAGSNFLGMVAQKYDDFKDSFTVFHSGKVRFGDAHILKNEKLPTYKVPYSYVHEKLENERIYNHHTLTPDDFKTLGQLKQLRSGYITKEKELVFIDYSYSQKSAYDKENRKSLDSTMYGYKAIKKGSMWQLVVKVDGSIVPEDEKLMVETLQTSSRLGKSKSAEYGQVKITHLADQARENISEKDLPLNEVILYCNSRVALLDESGNPTYELKHLCEGLKEEQIAYEKTQIRTSTFTPYNTKRQTKDYERVCIKKGSVIVLKDISDAQLKQIQQGVGAYLSEGFGEIIINPSFLMEKGFTFASNEPEEVKKDERQKITQTFTDSTIQFLVNRHNTTIDTLRIAKNVADFIKNHKAEFKNINSSQWGNIRSIASSNQNDFIEKIKGYIGSGSKKWETHQVETLVKAMDHDAINKQTFIKLLAMKMGGKNDE
>NZ_CP045453.1|WP_167749329.1|591345_592602_-|CRISPR-associated-protein
MMNKRYRAHIVIEAQTPLKMGSNAMDFLQDSPVQKDWNGLPMILGTSIAGVLRKEFHGDKAADVFGLNNGSKIIISNALLIADTQGMVYEDLCVQKSDFLKLFENLPLREHTKITSKGTTQKGAKFDEEVVFKGTRFKFSIEFIDNNKELFMELIGLLRSSNFRLGGGSTKGFGKFKMIEIEYGLFDIEKYSSSLNKPLGGDKECNLETITCKDYTPYILQLKPDDFFMFGSGFSDNDADMTPVYEQVIDYEKRALSEKKVLIPASSIKGALAHRTTYHYNKLHGNTIEAGNGVDSVSTLFGAAKNSKQNIDGAKGKILITDCFKNDHGKTKTFDHVSIDRFTGGAMEGALFQEKTVANDEKWYEIELLVHSDIQGKELEAFELALKDVTTGMLPLGGATTKGHGIFLGTITKNGVAL
>NZ_CP045453.1|WP_167749328.1|590962_591349_-|TIGR04423-family-type-III-CRISPR-associated-protein
MKKNQIEIIEYINTLKGYEGYIQMSDAPIKDIWTTPSTITFSPQNGFIYEAHFFNGKDSIAIRQMNDVWFVDETKDVSLIDTQIYDAKQSLKIKMAQVWEEENDLLCENIPVLKLKKVVFAGFAGDRK
>NZ_CP045453.1|WP_167749327.1|588902_590966_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MITAPYNFVPLNKEVFYPSWSEDVSHDIPFEDSESGEIDITITAKSPIFIRNHSDERDKPSEEFCQYNGEYYIPSTTVKGMVRSVLEIISFSKMNPDMVDDKTYSIRDLRNRDLYMNRMKPQEIFCGWLKKVGNDYKIEDCGVVGRISQDNIHKDFGSKFKAQQGGFINKPDFKTAKYKYDLLKKLNIELTQKFDFSKEAQGKKIYTKGTKLEGTLVLTGQASARKDNGRMGDGKIYEFVFFNAIGEITLSKETMENFKFAYFDGRKTEPKESPDWKYWKEKLANGQKVPVFFQKEMRKDSNGQNQTIIKHFGLSYLYKLPYNGSIHDGIFKSHFEKKLDLAQTLFGYVNNDTALKGRVQFSHFKAIDKTKIVKLAPRTENLGTPRASFYPFYIFQEDEKLYSTFMNDNFVLAGRKRYPIHKNNPDESKISYNPTSSIGTSFKPLKEGVIFKGKMRYHNLKKCEIGALLSALIFHSTPNTFHNVGLGKSLGYGKINVAIHYPNKEQYLQEFETLMKENINNWMSSNILKELLTMATPQDNQRNSQLSYMELADFAQTKNDKINGYLKNYSKLDNIVSVTFTSPSPQKQQAIQVATSDIISKTKMRKTITEAWQRVFGIFYHPHQIEEFLKGAFQTTPTDQQQIYLKLKDNHSFIELIRMIHQYNNGHLNDQEVGKLYLEVLNMRSYK
>NZ_CP045453.1|WP_167749326.1|588123_588906_-|hypothetical-protein
MTRFHKREAQKIVASFIGSNTLSIRGALIAIILMIIASWLPDGLIEVVAGVKEEDKVKVFCQLLISSGLLVWLMFFIKNLSKSYVPTVDIEIEPSPQASKVLILFLSANPKVHEVLHVNSIDELERNNFRMPLLAINHHKTRLKKVIVICSEDSQNIYEPFKNLVQKLLPTCDISMIEQTPSVIDFEDGNAVYELLETLYQDLAKAKYKHKEIMIDITGGTKVVTLASAIFAIPNDKELEYVSTSDYQIKTYDIRYSEAN
>NZ_CP045453.1|WP_167750841.1|586578_588108_-|CRISPR-associated-DxTHG-motif-protein
MTIISICGMIGTTKPNPNEKSFIQKTDADKAVYDVDLSLQYLIAPPKETYINMLPLLVDTFAKEHQIIALATASAEKIQKEVLSFEGLDVTKCSFEFIDDTAFEAYFSTVNQLLREHDEVIIDLSHGFRHLPLLTLVSLLVNHLKSPEKIKHILFAQEVIPSKHYKIIDLNEYLDIATIAYALVSFKDNYTIARSIVLRTDRYKPLLEILRDFSQHILSNAIQTLFERELPRQIREKIEELDSDPHVAALKELLSGIRLHLINLEAISKKADYERYYKIGKLLLEKGYLLNAITIINEALPLYIQNILHSKKLLCIPSGTDAYHVTKSMMDFIEKGKRDSTLMSEEIDAYFVCSNKVVFDAFSSLQQKMRQLRNDFAHAYGENAHETITSTLEMLFATFHTLVLEQNLFATIKPSDRTSPPCQYDYTLFELKANTMFLKLFPFVLFKNVFEEKRILKLYQKEIPPQWNIPKNMSEKQHRLIDILYHYFEHKNDPKEARHYMDAFYQDFK
>NZ_CP045453.1|WP_167749324.1|586125_586509_-|hypothetical-protein
MIKKLFVLMNHEMLPSQISQAHEVLGIEKIISLNDTNWSSFDPDVSSIITALASYKSRLLKDASRGDYLLVQGDFGATYHMVCFAKKLGLTPLYATTKRVATQKMVDGSVVTQREFLHVRFREYEDA
>NZ_CP045453.1|WP_167750842.1|598497_599430_-|hypothetical-protein
MKPIVVLPLIAAALFLGGCATTPSQPNPSSLQQATSLKEYIALKRGGETINYNVIAEREHQSIIEYRTYDEAMNVADARDIMEVLDDAKGYCESIKGKSVYGDKAIQALNARPTLLSLDYVSYKSAIREQGLGKYEGFYQCLSPNDGFSIVSMKDNVELHQSAILGNKRDLKETYSRFYLIQHDKAQSLGLKTWLKGTKYAQISSKYTSFEDLLDLEKNSSVFPWRYERITGAQKYCTYHGGELFVSNALTQFKPITMDEYLFMRLETMNPTTINVFMNQETFTCKNSANPAQSFTLIHTDKQLEYKKGE
>NZ_CP045453.1|WP_167749335.1|599440_599749_-|hypothetical-protein
MLSMIRDYLIMVLVKLVIAFVIFGLCLLGIFIAYWVFCDYTRATMQIHEIMINDFTKVVLGFISLLCLFQDVSTGNNNGNAKKFYKKTEKYFEMYDTAGIKW
>NZ_CP045453.1|WP_167749336.1|599761_600016_-|hypothetical-protein
MKKVLLALIMVVGCLFASEGQKSVTTCRFEARQIGAFADSPMTCSGDFKKSSTTQELYGDGWRLINSYTQNNNVYLVFEKNKNL
>NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator
MVEKMIERFMDQIVENVKAERTKRGISQLVLAQILGHKSPNYVAKIETRKHDVSYNLEHLYKIASEFGLEVIDLIPQIKK
>NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase
MTLTIHKGTNEIGGSCIELSTQSTTILFDYGTPLNLESTKLDFKNKKIDAIVISHPHQDHFGEITMVETTIPIYCGKLSKELMNATKLFTGQGLLANKFHHFEAWKSFQIGDITITPYLVDHSAVDAYAFLVEYDGKKVIYSGDFRANGRKSKLFENMLTQKKLKNADVLLMEGTMLQRNNEEFPTEISVENKIVETLKNTEVITFMIGSSQNIDSLVSAYRACKKAEKIFVIDMYTAWILEKMSSVSASIPTMDWKNVFVLKSYGGSYYEKIKKNRDYFGDFQYRLFSNVILLDDIQKEPSRYYVKISPWHIEKLLKKLDTSSANIIYSQWLGYLKPEFSDKKTVDLFKKLQENHNWVYAHTSGHADLESLKKFSEALSPKALVPIHTEHKDAFCKHFENTVVLEDGMPFTI
>NZ_CP045453.1|WP_167749338.1|601871_602420_+|hypothetical-protein
MQETNEKLILTFENVYKENSYRGYQIDDLTDFKSESIDVEMEDIKEDIIANIKAYLNIENNTSSFIYNDIETILEGDFLLDYTIETVDVVFHDHYTYDDYKHDNSLYIDMYEDHCLKIENKYEELDHDISQEQMDVFEDALHEETQEFIDNTSSYIANEGAYFISNYYYTVDVVITLTKSIF
>NZ_CP045453.1|WP_167749339.1|602441_603098_+|hypothetical-protein
MEFLEKLMQVIVDEGIQTPKAQVERYLSPILGLFLEEILKKTFHKEYQMIVPEFPIRKGTIAKSVGSEQSESNQSTNIDYLMYNQTENKFVFIELKTDSKSFKPSQRKIYEDLKCVAKDKNNIFGQLLYDDLEKILSKSTSKDKYKYLKTKWNDSMSAINDMEIIYIVPAKTGLKEEVGREDENKLCVLYFNDLPVELSLFSEEWKIILEYLKKLDMN
>NZ_CP045453.1|WP_167749340.1|603145_603511_-|hypothetical-protein
MKKNHFTNILVLVAVFFVFTGCAGKDMKKFGGEFALVNQTGEPISTAVTITLGVTIYGIGALVDSSREEEQKPQQQETIFLTENNQSMNESNTSQTSYFDSGIIHTNNVNHVDVMNGTPPQ
>NZ_CP045453.1|WP_167749341.1|603507_603948_-|hypothetical-protein
MFNDFIVHINNALGASNSKVIVIALVIFLYVSIGWFINSYGERHYQYPVVSENWNYILFLAACIGVAIFLGILISSGTGLLSGEEVMKLIVFGILVGFIALYVRIYRNTSLLFATFSYIYMVTFSIILITIAFILAMASSRRDDQN
>NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein
MDSSTGLSLSFFIILLLAGGYLLYQMVRIVPQGEEWIIERLGKFHTVLKPGLNFLIPVFDKVQMRLNTKELIQQMKAQEVITKDNAVVIISAVVFYKISDPAKAVYSIDNFELAVANMAATTLRSVIGNMELDTALSGREIIKSSVSEKISDHLEQWGLSLTAVEVQDIRPSDTLQEAMEKQAAAQREKKALIMKAEGEKQAAITKAEGFKQSLILEAEGKYEASKKEAEAKVALANGDKEAMVVIASQIKVGDAASYLLAQRYIDSVMHLGNSNNSKVVFIPTDLKHSLEGATGGLGTIFSQVK

Crispr_ID: NZ_CP045453_3

• CRISPR_ID: NZ_CP045453_3
• CRISPR_location: 604055-604434
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas6

Consensus repeat of NZ_CP045453_3

Consensus_repeat	Method
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CRT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	PILER-CR
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CRISPRCasFinder

spacers of NZ_CP045453_3

>3.1|604090|35|NZ_CP045453|CRT
TAAGATCTTCCACTGTTAGAAAAAACCATCGAAAA
>3.2|604160|35|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder
TTAAAAAAGACGGTAAGAGTAAAAGTTTAGCTTTT
>3.3|604230|33|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder
ATATCTATCTAGAGAATTAATCAATTTCATCGA
>3.4|604298|34|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder
AAAAAACTAAAGAGGTTAAATTAGAGCGAAATAG
>3.5|604367|33|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder
CAAAGACAGGAAGGAAAATCGATATACACACAG

CRISPR arrays and Neighbor proteins around NZ_CP045453_3

CRISPR arrays

The CRISPR arrays of NZ_CP045453_3

>merge|NZ_CP045453|3|604055-604434|CRT,PILER-CR,CRISPRCasFinder
GCAAATCCATAAAAATTATTGGGTCAGTATGTAATTAAGATCTTCCACTGTTAGAAAAAACCATCGAAAAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATTTAAAAAAGACGGTAAGAGTAAAAGTTTAGCTTTTGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATATATCTATCTAGAGAATTAATCAATTTCATCGAGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATAAAAAACTAAAGAGGTTAAATTAGAGCGAAATAGGTTTCAATCCCCTTATAATCGGGTCAGTATGTAATCAAAGACAGGAAGGAAAATCGATATACACACAGGTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|3|3|604055-604434|CRT
GCAAATCCATAAAAATTATTGGGTCAGTATGTAAT	TAAGATCTTCCACTGTTAGAAAAAACCATCGAAAA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TTAAAAAAGACGGTAAGAGTAAAAGTTTAGCTTTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATATCTATCTAGAGAATTAATCAATTTCATCGA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAAAACTAAAGAGGTTAAATTAGAGCGAAATAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAGACAGGAAGGAAAATCGATATACACACAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|3|3|604125-604434|PILER-CR
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TTAAAAAAGACGGTAAGAGTAAAAGTTTAGCTTTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATATCTATCTAGAGAATTAATCAATTTCATCGA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAAAACTAAAGAGGTTAAATTAGAGCGAAATAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAGACAGGAAGGAAAATCGATATACACACAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

>NZ_CP045453|3|3|604125-604434|CRISPRCasFinder
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	TTAAAAAAGACGGTAAGAGTAAAAGTTTAGCTTTT
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	ATATCTATCTAGAGAATTAATCAATTTCATCGA
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	AAAAAACTAAAGAGGTTAAATTAGAGCGAAATAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT	CAAAGACAGGAAGGAAAATCGATATACACACAG
GTTTCAATCCCCTTATAATCGGGTCAGTATGTAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP045453.1|WP_167749343.1|605766_606207_-|NfeD-family-protein	unknown	unknown	gnl|CDD|223961
NZ_CP045453.1|WP_167749335.1|599440_599749_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749344.1|606233_606632_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NZ_CP045453.1|WP_167749338.1|601871_602420_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749336.1|599761_600016_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749341.1|603507_603948_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749347.1|611208_612471_-|MFS-transporter	unknown	unknown	gnl|CDD|235865
NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293818
NZ_CP045453.1|WP_167749346.1|609547_610663_-|site-specific-integrase	unknown	unknown	gnl|CDD|271177
NZ_CP045453.1|WP_167749348.1|612467_614603_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase	unknown	unknown	gnl|CDD|181207
NZ_CP045453.1|WP_167749319.1|607659_608772_-|IS21-family-transposase	unknown	unknown	gnl|CDD|226950
NZ_CP045453.1|WP_167750842.1|598497_599430_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749339.1|602441_603098_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407
NZ_CP045453.1|WP_167749349.1|614973_615999_-|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|225070
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl|CDD|187890
NZ_CP045453.1|WP_167750843.1|608853_609537_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167749340.1|603145_603511_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_CP045453.1|WP_096047123.1|614604_614913_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238042

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.3e-52	173.8	0.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP045453.1|WP_167749344.1|606233_606632_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	1.01222e-18
NZ_CP045453.1|WP_167749343.1|605766_606207_-|NfeD-family-protein	gnl|CDD|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	9.8045e-08
NZ_CP045453.1|WP_167749347.1|611208_612471_-|MFS-transporter	gnl|CDD|235865	PRK06814, PRK06814, acyl-[ACP]--phospholipid O-acyltransferase.	7.4728e-144
NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase	gnl|CDD|293818	cd07732, metallo-hydrolase-like_MBL-fold, uncharacterized subgroup of the MBL-fold_metallo-hydrolase superfamily; MBL-fold metallo hydrolase domain. Includes functionally uncharacterized Enterococcus faecalis EF2904. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily.Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	4.13275e-69
NZ_CP045453.1|WP_167749346.1|609547_610663_-|site-specific-integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.72039e-22
NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	1.11365e-08
NZ_CP045453.1|WP_167749319.1|607659_608772_-|IS21-family-transposase	gnl|CDD|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.78986e-50
NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	1.13984e-59
NZ_CP045453.1|WP_167749349.1|614973_615999_-|amidohydrolase-family-protein	gnl|CDD|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	8.78686e-18
NZ_CP045453.1|WP_167749348.1|612467_614603_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase	gnl|CDD|181207	PRK08043, PRK08043, bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase.	0
NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.72834e-06
NZ_CP045453.1|WP_096047123.1|614604_614913_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.92124e-10

Protein sequences

>NZ_CP045453.1|WP_167749341.1|603507_603948_-|hypothetical-protein
MFNDFIVHINNALGASNSKVIVIALVIFLYVSIGWFINSYGERHYQYPVVSENWNYILFLAACIGVAIFLGILISSGTGLLSGEEVMKLIVFGILVGFIALYVRIYRNTSLLFATFSYIYMVTFSIILITIAFILAMASSRRDDQN
>NZ_CP045453.1|WP_167749340.1|603145_603511_-|hypothetical-protein
MKKNHFTNILVLVAVFFVFTGCAGKDMKKFGGEFALVNQTGEPISTAVTITLGVTIYGIGALVDSSREEEQKPQQQETIFLTENNQSMNESNTSQTSYFDSGIIHTNNVNHVDVMNGTPPQ
>NZ_CP045453.1|WP_167749339.1|602441_603098_+|hypothetical-protein
MEFLEKLMQVIVDEGIQTPKAQVERYLSPILGLFLEEILKKTFHKEYQMIVPEFPIRKGTIAKSVGSEQSESNQSTNIDYLMYNQTENKFVFIELKTDSKSFKPSQRKIYEDLKCVAKDKNNIFGQLLYDDLEKILSKSTSKDKYKYLKTKWNDSMSAINDMEIIYIVPAKTGLKEEVGREDENKLCVLYFNDLPVELSLFSEEWKIILEYLKKLDMN
>NZ_CP045453.1|WP_167749338.1|601871_602420_+|hypothetical-protein
MQETNEKLILTFENVYKENSYRGYQIDDLTDFKSESIDVEMEDIKEDIIANIKAYLNIENNTSSFIYNDIETILEGDFLLDYTIETVDVVFHDHYTYDDYKHDNSLYIDMYEDHCLKIENKYEELDHDISQEQMDVFEDALHEETQEFIDNTSSYIANEGAYFISNYYYTVDVVITLTKSIF
>NZ_CP045453.1|WP_167749337.1|600613_601855_+|MBL-fold-metallo-hydrolase
MTLTIHKGTNEIGGSCIELSTQSTTILFDYGTPLNLESTKLDFKNKKIDAIVISHPHQDHFGEITMVETTIPIYCGKLSKELMNATKLFTGQGLLANKFHHFEAWKSFQIGDITITPYLVDHSAVDAYAFLVEYDGKKVIYSGDFRANGRKSKLFENMLTQKKLKNADVLLMEGTMLQRNNEEFPTEISVENKIVETLKNTEVITFMIGSSQNIDSLVSAYRACKKAEKIFVIDMYTAWILEKMSSVSASIPTMDWKNVFVLKSYGGSYYEKIKKNRDYFGDFQYRLFSNVILLDDIQKEPSRYYVKISPWHIEKLLKKLDTSSANIIYSQWLGYLKPEFSDKKTVDLFKKLQENHNWVYAHTSGHADLESLKKFSEALSPKALVPIHTEHKDAFCKHFENTVVLEDGMPFTI
>NZ_CP045453.1|WP_167750652.1|600149_600392_+|helix-turn-helix-transcriptional-regulator
MVEKMIERFMDQIVENVKAERTKRGISQLVLAQILGHKSPNYVAKIETRKHDVSYNLEHLYKIASEFGLEVIDLIPQIKK
>NZ_CP045453.1|WP_167749336.1|599761_600016_-|hypothetical-protein
MKKVLLALIMVVGCLFASEGQKSVTTCRFEARQIGAFADSPMTCSGDFKKSSTTQELYGDGWRLINSYTQNNNVYLVFEKNKNL
>NZ_CP045453.1|WP_167749335.1|599440_599749_-|hypothetical-protein
MLSMIRDYLIMVLVKLVIAFVIFGLCLLGIFIAYWVFCDYTRATMQIHEIMINDFTKVVLGFISLLCLFQDVSTGNNNGNAKKFYKKTEKYFEMYDTAGIKW
>NZ_CP045453.1|WP_167750842.1|598497_599430_-|hypothetical-protein
MKPIVVLPLIAAALFLGGCATTPSQPNPSSLQQATSLKEYIALKRGGETINYNVIAEREHQSIIEYRTYDEAMNVADARDIMEVLDDAKGYCESIKGKSVYGDKAIQALNARPTLLSLDYVSYKSAIREQGLGKYEGFYQCLSPNDGFSIVSMKDNVELHQSAILGNKRDLKETYSRFYLIQHDKAQSLGLKTWLKGTKYAQISSKYTSFEDLLDLEKNSSVFPWRYERITGAQKYCTYHGGELFVSNALTQFKPITMDEYLFMRLETMNPTTINVFMNQETFTCKNSANPAQSFTLIHTDKQLEYKKGE
>NZ_CP045453.1|WP_167749333.1|595945_596773_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MLRFIKIDITFSSSFTTSLDFLGSTLRGAFGVALKAVSCLNKTQECQGCFATQNCLYYDFFEIKNRAHAYRFSKPLHENNYNFSLYLFEAACEKLPYVLSALHTMFGRIGVGWNRHLIPIERIVCNGVVVSSGKNFDLSQIVVDVFETKEYFPDITLHFLTPLRIKSNNALLHTTPTLEQILSSIFNRHNELKGIPLAKLPFTPRYKELRTHLRFQELSRYSNRQESTMHLGGMMGTIDYEDVDEHSYALLKLGELLGVGKQTVFGLGEIKVGHQ
>NZ_CP045453.1|WP_167749342.1|604839_605757_-|SPFH/Band-7/PHB-domain-protein
MDSSTGLSLSFFIILLLAGGYLLYQMVRIVPQGEEWIIERLGKFHTVLKPGLNFLIPVFDKVQMRLNTKELIQQMKAQEVITKDNAVVIISAVVFYKISDPAKAVYSIDNFELAVANMAATTLRSVIGNMELDTALSGREIIKSSVSEKISDHLEQWGLSLTAVEVQDIRPSDTLQEAMEKQAAAQREKKALIMKAEGEKQAAITKAEGFKQSLILEAEGKYEASKKEAEAKVALANGDKEAMVVIASQIKVGDAASYLLAQRYIDSVMHLGNSNNSKVVFIPTDLKHSLEGATGGLGTIFSQVK
>NZ_CP045453.1|WP_167749343.1|605766_606207_-|NfeD-family-protein
MPWYIWGIFGICAIVFEVASPTFFAGFIGVGFFGSAVLSYFQPNSLIWQILIALVGMFVGSFIFKRQKMGDTTSSKLGQSDEFIGIRGKVECDLKEGIQGSVMLSSPVLGSTQWKAVSENGVEIPNAATVKIVATHGTYLVVKQII
>NZ_CP045453.1|WP_167749344.1|606233_606632_-|DUF805-domain-containing-protein
MFSNYFSELKKTFVYKGRTSRKSFWLFAVMHTILLLSVLGLIFLSDALAKGDTKSIFSTIEAISSILLIPLYLFPTLSITTRRFHDLNMSGWHQLYSFLPYIGGLILFIYMCYKSVDENNRYNIVDESAIAL
>NZ_CP045453.1|WP_167749319.1|607659_608772_-|IS21-family-transposase
MLKKGEIKMIKKFLAEGFSKSAIARKLGISRETVRRYANLPDDYIPHINRPPVINSVDPYLPHIAKMLETAEQQKSEIPLTVIYEEIKKLGYDGSLRWLQQVILRYELRARAKLDEPIIRFETKPAQQMQVDWVEFPKDNLSAFVATMGYSRASYVEYVNNEKIETLIGCHMNAFAYFGGVPKECLYDNMKTVILSRNDYGKGDHRFNPLFADFAKHCGFSIKVCKPYRAKTKGKVERFNHYLRYNFHNGLRVRLSMKHYTLTLDNANAEVLKWLDNTANKRIHQTTLQMPFELLAQEQLQLLPVPKAYQGIHPKALIESVAKKYSPINSHKDLEKLYIPNRDIQCYDEFIPMVANIILPVGFYGGALWS
>NZ_CP045453.1|WP_167750843.1|608853_609537_-|hypothetical-protein
MSKKKNIIDCSLLDMHKYSKDAFQYLYDKLTDKGFKRAYVAKDRPINAVTGILWDITQEDDEVTKIIEGMDKIDNIKAESSKSRLEKIANTWIKKAYREYFVNGYKISRSLFVKFTKNIFEPKSEENRKQLEAASKKLFDKTYNTYRNRQHRITNSDKFNELVARYPKLNIDKAYRYAIVSGKFNLNADDIEEFEYILKFALSKKEDSNKKNQLSNELLNWSVENVI
>NZ_CP045453.1|WP_167749346.1|609547_610663_-|site-specific-integrase
MARVKSKSNVGVYKEVLDNGDTSFYYTYKDIDGKKRWVKVGLKSNGYSERDAVVQRRKTMIELEDLEEPLYIKKNKFQEIITLNQLATYYFNEKSDMKNHRDAYLKYMHQISPVFGLDNILTLRAEKIQRFKQKLIEKGYRAASVNYYLAQLKAIINYAVFTDRINMVNPCSKVKLLALNNQRKRILSENEIELLLKSLLHKQKAYLFVLIAIFTGARPKAILNLQCKNIDFSFNKITFIAMKNRPSYSVAIHSRLREALQQWVEYLNPEEYLFYRENPMLDKSSHMSYIGIKKQTQPTMDLLFNQGLQVNDRINKVTLYTLRHSFGSLLSKRGANAFVIKELMNHAKIDTTDRYVKVTNQEAKKYIDAIL
>NZ_CP045453.1|WP_167749347.1|611208_612471_-|MFS-transporter
MSAFYLLKTKRFAPLFTVQFLGAFNDNIFKNTLAILVTFHAGSWTSLPLEVLAPLIGAIFIVPFFLFSGLAGALADKYDKAALTRLVKLLEFGLMSIATLGFYMHWFSLLLVVVFGMGLHSTLFGPIKYAIIPQHMGENELVTANALVESGTFGAILLGTLGGGLIAASAYGGIIAGIMGMAIALIGYVCSRSIPTAPSLNAQMSLSYNIFSQTAQTLKLSYANKTVFLSIIAISWFWLYGALLLSQFPAFVKIVLEGDETTVTLLLSLFTVGIGVGSFLCEKLSHHTIRPSLIILGALGMAFFGIDFALTSSSFVPIERLFSSITFWHILVDLTLIALFGGLFSVPLYAIMQSQSDPSFRSRIIAANNILNALFMVVGAVLTMVLLDASWRIPEVFLSAAIGTGIIATWIAWVVYKRID
>NZ_CP045453.1|WP_167749348.1|612467_614603_-|bifunctional-acyl-ACP--phospholipid-O-acyltransferase/long-chain-fatty-acid--ACP-ligase
MIKIALRIILRFLFKLRVQGHFTANKNEPMLIIANHQSFLDGLILGVMLPVSPVFIINTQIAKNPFVRFFLMLADHLTVDPSNPMAIKAVIRLVESGRPVVIFPEGRITTTGSLMKIYEGSAFVAVKTNAMVVPVMIQGATFSRLSRMPKTFPHRLFPQITLHYCTPTKLTVSHEGTSHERRLLSGEAMRHLMQECSFDARPANDLFGTFLDAIETYGKNKAIVEDIKQVEYTYAQLLKMALGLGRLLSPITQKDEAVGVLMPTAVASLALVLGLSGMKRVPAMLNFTAGVDGLQSACTAAEIKTIVTSRAFVEQAKLAPKLEALQGVRIVYLEELKTSMRLVDKLWLMLYAIHFPRLVANSQDEKESAVILFTSGSEGKPKGVVLSHEALLANIAQISSIVDFSTEDKMLNALPIFHSFGLTAGSLLPIFRGMHLFMYPSPLHYRVIPEIAYDRSCTILLGTSTFLHNYARHAHPYDFYRVRYVIAGAEKLSENVRELWFEKFGLRIFEGYGATETAPVIAVNTPMAYKKGTVGQILPGIESKLVPVAGIEDGGILHVKGANVMSGYLRAENPGVLEKPTSEAGEGWYNTGDIVSIDEAGFVQIKGRVKRFAKIAGEMISLESVEKLATLTSSGFLHASSSIPDVARGEAIVLFTTDKNLNREALQKSAQSNGYPEIAVPRKIVHLETLPLLGTGKTDYVTLKSMASEIA
>NZ_CP045453.1|WP_096047123.1|614604_614913_-|winged-helix-turn-helix-transcriptional-regulator
MQTQYAKDLPLEWKPMSAIFMALGDAHRQRILLLFEDGERLNAGQIAEVSPLARTTVSHHLKILHQAEVLLSEKIGKEVWFWVNKPLLEATFSNVLNYLHGN
>NZ_CP045453.1|WP_167749349.1|614973_615999_-|amidohydrolase-family-protein
MKTIDTHVHLLSSEVSFNRIYDKVAVRFFAKRFGIDANALAQEPYKAYTDALMNSVKHSEHIEKIVLFGVDVKVDDEGNVLHKDKTVCASNEDVAALYAQFPELIIPFFSINPKRPNALELIEKYHALGFKGAKFLQNYWGVDTREARYRPYFEKLAALDLPLIIHVGSESSVHSVKTCESIEMLRQPLEVGVKVICAHMALSYEPRHIFKALSSNPKRFNEDYFTLLEMLKTHDNLYADVSALLTPVRAKVLRHLSTQSDIHPKLLFGSDYPVPFTTVWNSYDIALLKRICIAQERNVFDRYVKAMLVYFPANHPIYNNYRKVLCLEENTLHVKSQTDIF

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	HG422566	Cardinium endosymbiont cBtQ1 of Bemisia tabaci plasmid pCHV, complete sequence	1588-1620	5	0.848
NZ_CP045453_2	2.9|597088|33|NZ_CP045453|CRISPRCasFinder	597088-597120	33	MF036691	Serratia phage CBH8, complete genome	44348-44380	6	0.818
NZ_CP045453_2	2.9|597088|33|NZ_CP045453|CRISPRCasFinder	597088-597120	33	MF036690	Serratia phage CHI14, complete genome	44348-44380	6	0.818
NZ_CP045453_2	2.9|597088|33|NZ_CP045453|CRISPRCasFinder	597088-597120	33	MF036692	Serratia phage X20, complete genome	44191-44223	6	0.818
NZ_CP045453_1	1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT	579858-579891	34	NZ_CP029750	Staphylococcus aureus strain Smith plasmid pSS41, complete sequence	10171-10204	7	0.794
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	NZ_CP013332	Fusobacterium hwasookii ChDC F174 plasmid unnamed1, complete sequence	27232-27264	7	0.788
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	KX229736	Campylobacter phage PC5, complete genome	91578-91610	7	0.788
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	KX879627	Campylobacter phage vB_CjeM_Los1, complete genome	7646-7678	7	0.788
NZ_CP045453_2	2.1|596950|32|NZ_CP045453|CRT	596950-596981	32	MN694477	Marine virus AFVG_250M1149, complete genome	26205-26236	7	0.781
NZ_CP045453_2	2.1|596950|32|NZ_CP045453|CRT	596950-596981	32	MN693738	Marine virus AFVG_250M1148, complete genome	25989-26020	7	0.781
NZ_CP045453_2	2.3|597087|34|NZ_CP045453|CRT,PILER-CR	597087-597120	34	MF036691	Serratia phage CBH8, complete genome	44348-44381	7	0.794
NZ_CP045453_2	2.3|597087|34|NZ_CP045453|CRT,PILER-CR	597087-597120	34	MF036690	Serratia phage CHI14, complete genome	44348-44381	7	0.794
NZ_CP045453_2	2.3|597087|34|NZ_CP045453|CRT,PILER-CR	597087-597120	34	MF036692	Serratia phage X20, complete genome	44191-44224	7	0.794
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	MN693026	Marine virus AFVG_117M72, complete genome	10033-10065	8	0.758
NZ_CP045453_1	1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580202-580234	33	NC_013168	Rippkaea orientalis PCC 8802 plasmid pP880204, complete sequence	5340-5372	8	0.758
NZ_CP045453_2	2.12|597295|32|NZ_CP045453|CRISPRCasFinder	597295-597326	32	NC_019298	Rahnella sp. WMR121 plasmid pHW121, complete sequence	740-771	8	0.75
NZ_CP045453_2	2.12|597295|32|NZ_CP045453|CRISPRCasFinder	597295-597326	32	NZ_LN907828	Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence	23475-23506	8	0.75
NZ_CP045453_1	1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580339-580373	35	AP014488	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S45-C60, *** SEQUENCING IN PROGRESS ***, 7 ordered pieces	26553-26587	9	0.743
NZ_CP045453_1	1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580339-580373	35	AP014487	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S34-C76, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces	21621-21655	9	0.743
NZ_CP045453_1	1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR	580339-580373	35	AP014093	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S29-C126, *** SEQUENCING IN PROGRESS ***	6592-6626	9	0.743
NZ_CP045453_2	2.3|597087|34|NZ_CP045453|CRT,PILER-CR	597087-597120	34	NZ_CP023318	Bacillus megaterium strain A plasmid p1, complete sequence	133390-133423	9	0.735
NZ_CP045453_2	2.3|597087|34|NZ_CP045453|CRT,PILER-CR	597087-597120	34	NZ_CP024036	Bacillus aryabhattai strain K13 plasmid unnamed1	76394-76427	9	0.735
NZ_CP045453_2	2.6|597294|33|NZ_CP045453|CRT,PILER-CR	597294-597326	33	NC_019298	Rahnella sp. WMR121 plasmid pHW121, complete sequence	739-771	9	0.727
NZ_CP045453_2	2.9|597088|33|NZ_CP045453|CRISPRCasFinder	597088-597120	33	NZ_CP023318	Bacillus megaterium strain A plasmid p1, complete sequence	133390-133422	9	0.727
NZ_CP045453_2	2.9|597088|33|NZ_CP045453|CRISPRCasFinder	597088-597120	33	NZ_CP024036	Bacillus aryabhattai strain K13 plasmid unnamed1	76395-76427	9	0.727
NZ_CP045453_3	3.3|604230|33|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder	604230-604262	33	MN480762	Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence	184756-184788	9	0.727
NZ_CP045453_1	1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT	579858-579891	34	NZ_CP039853	Salinimonas sp. KX18D6 plasmid plas12, complete sequence	11567-11600	10	0.706
NZ_CP045453_1	1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT	579858-579891	34	NC_011311	Aliivibrio salmonicida LFI1238 plasmid pVSAL840, complete sequence	11772-11805	11	0.676

1. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to HG422566 (Cardinium endosymbiont cBtQ1 of Bemisia tabaci plasmid pCHV, complete sequence) position: , mismatch: 5, identity: 0.848

taaaatttattaaaaggaaat-aaaatgattaaa	CRISPR spacer
gaaattttattaaaagtaaataaaaatgagtaa-	Protospacer
 *** *********** **** ******* *** 

2. spacer 2.9|597088|33|NZ_CP045453|CRISPRCasFinder matches to MF036691 (Serratia phage CBH8, complete genome) position: , mismatch: 6, identity: 0.818

tatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
tatcaaggtgaataaatgattgttacagataaa	Protospacer
******** *************** **  ** .

3. spacer 2.9|597088|33|NZ_CP045453|CRISPRCasFinder matches to MF036690 (Serratia phage CHI14, complete genome) position: , mismatch: 6, identity: 0.818

tatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
tatcaaggtgaataaatgattgttacagataaa	Protospacer
******** *************** **  ** .

4. spacer 2.9|597088|33|NZ_CP045453|CRISPRCasFinder matches to MF036692 (Serratia phage X20, complete genome) position: , mismatch: 6, identity: 0.818

tatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
tatcaaggtgaataaatgattgttacagataaa	Protospacer
******** *************** **  ** .

5. spacer 1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT matches to NZ_CP029750 (Staphylococcus aureus strain Smith plasmid pSS41, complete sequence) position: , mismatch: 7, identity: 0.794

caaatcaaaaagtagaaaaagctatggtttatcc	CRISPR spacer
caaatcaaaaaggagataaagctattgagtctgc	Protospacer
************ *** ******** *  * * *

6. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013332 (Fusobacterium hwasookii ChDC F174 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

taaaatttattaaaaggaaataaaatgattaaa	CRISPR spacer
aaaaatttattaaaaggaaatacaataaaacca	Protospacer
 ********************* ***.*    *

7. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to KX229736 (Campylobacter phage PC5, complete genome) position: , mismatch: 7, identity: 0.788

taaaatttattaaaaggaaataaaatgattaaa	CRISPR spacer
tgaaatttatttaaaggaaagaaaatggcttta	Protospacer
*.********* ******** ******..*  *

8. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to KX879627 (Campylobacter phage vB_CjeM_Los1, complete genome) position: , mismatch: 7, identity: 0.788

taaaatttattaaaaggaaataaaatgattaaa	CRISPR spacer
tgaaatttatttaaaggaaagaaaatggcttta	Protospacer
*.********* ******** ******..*  *

9. spacer 2.1|596950|32|NZ_CP045453|CRT matches to MN694477 (Marine virus AFVG_250M1149, complete genome) position: , mismatch: 7, identity: 0.781

--gtaacagaagttgagcatacaactgcatatta	CRISPR spacer
tggcgac--aagttgataatacaactgcatattt	Protospacer
  *..**  *******  *************** 

10. spacer 2.1|596950|32|NZ_CP045453|CRT matches to MN693738 (Marine virus AFVG_250M1148, complete genome) position: , mismatch: 7, identity: 0.781

--gtaacagaagttgagcatacaactgcatatta	CRISPR spacer
tggcgac--aagttgataatacaactgcatattt	Protospacer
  *..**  *******  *************** 

11. spacer 2.3|597087|34|NZ_CP045453|CRT,PILER-CR matches to MF036691 (Serratia phage CBH8, complete genome) position: , mismatch: 7, identity: 0.794

ttatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
ctatcaaggtgaataaatgattgttacagataaa	Protospacer
.******** *************** **  ** .

12. spacer 2.3|597087|34|NZ_CP045453|CRT,PILER-CR matches to MF036690 (Serratia phage CHI14, complete genome) position: , mismatch: 7, identity: 0.794

ttatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
ctatcaaggtgaataaatgattgttacagataaa	Protospacer
.******** *************** **  ** .

13. spacer 2.3|597087|34|NZ_CP045453|CRT,PILER-CR matches to MF036692 (Serratia phage X20, complete genome) position: , mismatch: 7, identity: 0.794

ttatcaaggagaataaatgattgtttcatttatg	CRISPR spacer
ctatcaaggtgaataaatgattgttacagataaa	Protospacer
.******** *************** **  ** .

14. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to MN693026 (Marine virus AFVG_117M72, complete genome) position: , mismatch: 8, identity: 0.758

taaaatttattaaaaggaaat-aaaatgattaaa	CRISPR spacer
caaaatttattacaaggaaatcaaagcggacaa-	Protospacer
.*********** ******** ***..*. .** 

15. spacer 1.6|580202|33|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to NC_013168 (Rippkaea orientalis PCC 8802 plasmid pP880204, complete sequence) position: , mismatch: 8, identity: 0.758

taaaatttattaaaaggaaataaaatgattaaa	CRISPR spacer
gaaaatttattacaagaaaataaaaatttgtaa	Protospacer
 *********** ***.********   *  **

16. spacer 2.12|597295|32|NZ_CP045453|CRISPRCasFinder matches to NC_019298 (Rahnella sp. WMR121 plasmid pHW121, complete sequence) position: , mismatch: 8, identity: 0.75

aaaagacgcaagatctgcagaaattttaaaaa	CRISPR spacer
tatgaaggcaatttctgcagaaattttaaaat	Protospacer
 * ..* ****  ****************** 

17. spacer 2.12|597295|32|NZ_CP045453|CRISPRCasFinder matches to NZ_LN907828 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence) position: , mismatch: 8, identity: 0.75

aaaagacgcaagatctgcagaaattttaaaaa	CRISPR spacer
gaagtccgcaggatctgcagtaattttaagca	Protospacer
.**.  ****.********* ********. *

18. spacer 1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to AP014488 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S45-C60, *** SEQUENCING IN PROGRESS ***, 7 ordered pieces) position: , mismatch: 9, identity: 0.743

aaagtaaatgtaaaagaagatggtagaaaatctca	CRISPR spacer
gaattatatgtaaaagaagatggtagtataggaaa	Protospacer
.** ** ******************* * *    *

19. spacer 1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to AP014487 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S34-C76, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 9, identity: 0.743

aaagtaaatgtaaaagaagatggtagaaaatctca	CRISPR spacer
gaattatatgtaaaagaagatggtagtataggaaa	Protospacer
.** ** ******************* * *    *

20. spacer 1.8|580339|35|NZ_CP045453|CRISPRCasFinder,CRT,PILER-CR matches to AP014093 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C31A-MedDCM-OCT-S29-C126, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.743

aaagtaaatgtaaaagaagatggtagaaaatctca	CRISPR spacer
gaattatatgtaaaagaagatggtagtataggaaa	Protospacer
.** ** ******************* * *    *

21. spacer 2.3|597087|34|NZ_CP045453|CRT,PILER-CR matches to NZ_CP023318 (Bacillus megaterium strain A plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.735

ttatcaag-----gagaataaatgattgtttcatttatg	CRISPR spacer
-----aagagtttaagaatgaatgattgtttcctttatc	Protospacer
     ***     .*****.************ ***** 

22. spacer 2.3|597087|34|NZ_CP045453|CRT,PILER-CR matches to NZ_CP024036 (Bacillus aryabhattai strain K13 plasmid unnamed1) position: , mismatch: 9, identity: 0.735

ttatcaag-----gagaataaatgattgtttcatttatg	CRISPR spacer
-----aagagtttaagaatgaatgattgtttcctttatc	Protospacer
     ***     .*****.************ ***** 

23. spacer 2.6|597294|33|NZ_CP045453|CRT,PILER-CR matches to NC_019298 (Rahnella sp. WMR121 plasmid pHW121, complete sequence) position: , mismatch: 9, identity: 0.727

caaaagacgcaagatctgcagaaattttaaaaa	CRISPR spacer
atatgaaggcaatttctgcagaaattttaaaat	Protospacer
  * ..* ****  ****************** 

24. spacer 2.9|597088|33|NZ_CP045453|CRISPRCasFinder matches to NZ_CP023318 (Bacillus megaterium strain A plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.727

tatcaagg----agaataaatgattgtttcatttatg	CRISPR spacer
----agagtttaagaatgaatgattgtttcctttatc	Protospacer
    *..*    *****.************ ***** 

25. spacer 2.9|597088|33|NZ_CP045453|CRISPRCasFinder matches to NZ_CP024036 (Bacillus aryabhattai strain K13 plasmid unnamed1) position: , mismatch: 9, identity: 0.727

tatcaagg----agaataaatgattgtttcatttatg	CRISPR spacer
----agagtttaagaatgaatgattgtttcctttatc	Protospacer
    *..*    *****.************ ***** 

26. spacer 3.3|604230|33|NZ_CP045453|CRT,PILER-CR,CRISPRCasFinder matches to MN480762 (Streptococcus salivarius strain NU10 plasmid pSsal-NU10, complete sequence) position: , mismatch: 9, identity: 0.727

atatctatctagagaattaatcaatttcatcga	CRISPR spacer
aatagtatctagagaatacatcaatttcatatc	Protospacer
*    ************  ***********   

27. spacer 1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT matches to NZ_CP039853 (Salinimonas sp. KX18D6 plasmid plas12, complete sequence) position: , mismatch: 10, identity: 0.706

caaatcaaaaagtagaaaaagctatggtttatcc	CRISPR spacer
gaaatcaaaatgaagaaaaagctatggcgagatg	Protospacer
 ********* * **************.  . . 

28. spacer 1.1|579858|34|NZ_CP045453|CRISPRCasFinder,CRT matches to NC_011311 (Aliivibrio salmonicida LFI1238 plasmid pVSAL840, complete sequence) position: , mismatch: 11, identity: 0.676

caaatcaaaaagtagaaaaagc--tatggtttatcc	CRISPR spacer
acaaccaaaaagtagaaaaagcgatgcgactcaa--	Protospacer
  **.*****************  *..*..*.*   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	751343 : 762782	11	Escherichia_phage(22.22%)	NA	NA
DBSCAN-SWA_2	873879 : 881531	9	Campylobacter_virus(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP045453|751343:762782|DBSCAN-SWA
ATCAATTAGTTTGGCTTCTAATAAAATATACTATTTTTTCAATCATATACCCAATTGCATCATCGCTCATACCAGGGTATAAACCAATCCAAAAACTATCACTCATGATTTTGTCTGTATTGGGAAGTAAACCTATTACTCTATAATCTTTATCTTTTTCAAGTGACTCAAATAGAGGATGTCGTAGCATATTGCCCGCAAAAAGATTACGCGTTTGGATGTTGTTATTTTCAAGGTATTCGACCAGTTCATTGCGTGAAAATTTCACATTATCTTTTATGGTCATCATAAAGCCAAACCAACTTGGATCGCTCTGCGGTTGTGCTTCTACCAAGATTAATTCTGGAACATCTTTGAATCCATTATAAAGTTTTTTAAAATTCACTTTTCTTTTTTCAACGAAACTTGGAAATTTCTCCAGTTGTGCGCATCCAACAGCAGCTTGCATATCGGACACTTTGAGGTTAAAACCAAAATGGCTATAGACATATTTATGGTCATACCCTTTAGGAAGGCTTCCAAACTGTTGCGTAAAGCGACATCCACAGGTATTATCCACACCACTCTCGCACCAACAGTCTCTTCCCCAATCACGCATGGAAAGCATAATCTTTTTAAGAAGAGGATTGTCTGTGTATGTTGCTCCGCCCTCACCCATTGTCATGTGATGTGGTGGGTAAAAACTACTCGTTCCTATATCGCCCCATGTTCCTGTTGGCTTACCTTCATACGTTGAGCCAAGCGCATCACAATTGTCTTCAATGAGCCATAAATTGTGTTTATCGCAAAACGCTTTCACAACCTTAATGTTAAAAGGATTTCCTAACGTGTGGGCTATCATCACCGCTTTTGTTTTGGAACTCAGTGCTTGTTCTAACTGCGTCACGTCAATGTTAAAGTGTGTCAGTTCCATATCAACAAACACTGGCACGGCACCGTATTGAACAATAGGTGCTACGGTTGTTGGAAAGCCAGCGGCGACCGTGATAACTTCATCGCCACGTTTGACTTGCCGCTCTTTTAGAAGTGGTGAAGTAAGTGCATAAAAAGCCAACAAATTGGCAGAACTGCCACTATTGACCAAGAATGCCCATCTTACATGTAAAAACTTTGCTAACTCTTTTTCAAATTTTTTAGAATAATCCCCATAGGTCAACCAAAAATCAAGCGAACTATCGACAAGGTTCATCATCTCTTTTTCATCAAAGACACGCCCTGCATAATTAACGCGACTCTCTCCCGCAACAAACGGTCTCGTTTGATTTTTTTTATGAACGAGTTCATAATATTGTTTTGTTTTTTCTAAAATCTCTTGCTTGAGTTGTTCTTCTTTGCTCATTATTTGCCTTTCCACATTGTATCTATTGCTTTTAGATACGGATCTTCTTTTATGGTTTGTATATCTAATTTATCTAAATTTTCTTGAAAATAACATCTCATCTTTGCTATCGCATTTTTGTGCGATGTGAACTGAAAATCGCCAAACTCTTTTAAAAGACGCTCATTATTGGACGTGTATTCGTTATTAAGCCCTTCATGAATGACTCTTATATCGGAATAAAAATCACCGACTTCATTCACTAAATTTGCTAATGTAATTAAATCTACTTTTGTGCCTGTCGTGACGTTATAGATTTTCTCTTTAGTATCGTTATAGATAAAAAAGTCGATTATTTTAACCAAATCATCACTGTAAATATAGTCAAAATAGACATTCTTATTGATCGTTATAGGCAAATGCAATAAGTTTTTAACAATGGCATTTGAAATAAACTTATAGCGATAGTTTTCATACTCACCGTATGCTCCAAAAATCCGTAACTGTACAATGTTCTCAGACTTCTCAATAAAATGCGATGTAATGGATTTATAAAATCCATATTCATCTAAGGGCAACGCTTGTAAATAATCATCTTCTTTTGCTTCGATAATGGGCTTTTGCTTACTATACTCGGCACCACTCCCAAAAGAGATGATTTTCTTTACATTTTTTTCGTGTTTAGCGATATTGAAAAAAATACGTAAATTGTACTCTGTCACATTTTTCATATCAGCAGTATCGCGGCCTCCACCACGATTGGCAGTATGGACAATCACATCAATTTTATTTTCTAAAATATATCTATCAACTGCTTTTTCATCACTTAAATCAAGCTCTTTACTAGATGGTATAAAAAGTGTGTCATGATGATGCCCGAGAAGATACTCTTTTAGATGAGAGCCAATAAAGCCGCTAGAACCTGTAATGAAAATATTCATAAATTAGTGTTCCAATGGTTTAATAATCATTTGGGCGTTGAACTCTTCTCTTTCTAAAAAAGGATACATATCTTCAATAGGTTTATTGACAATAAGCTTTGGCTCAACCGTTGTCATTTGCTCTTGTAGACAGATATTAATGATTTCTGCCTCGTCTGATAGGAGTGTTTCGTGAATCTTTTGAGAAATCTCCTCTATGGTCGAGATCGTACTGCTTTTAAGTCCATAGGCGTTTGCTATGCTTGCAAAATTTGGGACACTGTAATCTTTTTGTGTGCCAATGTATCTCTGTTCAAAATAAATTTCTTGAAATTGCCTCACCATACCAAGGTTTGCATTATTCATGATAAATACTTTAATGGGTAAATTTCTTCTTTTAATGACTTCTAATTCTTGAATATTCATCTGAAATCCACCATCACCCACAATCACAAGAGCTCTTTTTTTTGTGCCAATCGTTGCACCGATGGCTGTCGGTAAAGCAAAGCCCATGGCACCCATACCGCCAGAAAAAAGAACACGTTGATCTGCTTTGGTCTCAAAGGACTGGGCGACCCACATTTGATGTTGCCCCACATCAACACAAATCATGTCATGATCAGAGGAAGATTGAGCAATCCATTGAATGATTTGATTCGGTACTTTTGCTTTGCCATCAATGCCAGTTGTGGATGAATAGTTTTGCTTATACGTTACCAGTTTTTCAAGCCACTGACCTAAATTAAGTTTAAAATCATAGTGCGATAGTGTGTTGATAAAATCAGCAATATCACAATGCAAAGTGACATCTGCCTTGATTTTAGAGTCTAACTCATTGACATCTATATCAACGTGTATGATTTTTGCTGCTCTTGCAAACGTTTTCAAATCGGTACCCGTTTGTCGTGTATCAAGGCGAGAGCCTAAGACAATAATTAAATCAGCATTGGCTAAAGCTAAATTGCTGTATCGATTCCCGTAAGAGCCAATGAGTCCAAAATTATATTTATAATCGTCCTTAACAACATCTTTTCCCATTAGAGAGTACACAACAGGCAAATTGGATTTTTCTAATAAGCGATGAATGGCTTCTGGTGCCAAGGATGAAAGGCGGCTACCTCCACCGACAAGTATAATAGGACGCTGAGATACCCTCAACATTTCTACAATTTTTTCAAAATCAATCTTATCACCCTGAATACGCATCATTTTATATTCATCACTCTCAAAAAAAGATTTTTGTTCGGATGGATTGAAATCAGTCCGTTGAATATTCATTGGGATATCAATAAGTACAGGACCTTTTCTGCCATTTTGTGTTAAAAAATACGCTTTTTCAAGTTCATAACGAAGGTTTTGAATCATATCAATCATAACCGCATATTTTGTAATGGGCTTAACGATACTGACAATATCGGTTTCTTGAAACCCTATTTGCCTTACAGGCGTATCGTATTTGTATTCATACGTATTGACCTGTCCTGTAATAAAGAGAGTAGAAATTGAGTCAAAAAAGCAACTTCCAATAGGTGTTATAAGATTGGTTGCGCCTGGTCCACTTGTGGCTGTTGCCACACCTGTTTTCCCACTCACACGGGCATATCCCTCAGCGGCAAACCCTGCTCCTTGTTCATGAATGGTATTGACGATTTCAATACCTGTATTTTTATCAAAAGAATCATACAAATGAGCAACTGCACCGCCAATATACCCAAAAGCTTTATCAATGCCTTGATCAACTAAAAATTGCACAATATAATCAGATGCTTTCATTTGATAGTCCATGCTATATTTTTTTCTTTTGCATCAACAATGTAATTTTCCAAATCTTTTTGGCTTAGAATTTCATGGGTTTCATAAAACGCTTTATACCATTTAACGGTCTTCTCAAATGTATCCTCGCTATCCCACACATCTTTCCAATGAAGCTTGATATGGGCTTTTGAGCAGTCTAATTTTAAAAGATTGGCTTCATGAAGCTGGTTTGGATCACGGTTTATTTCATACGCAATCGCATCCCAATGCTTCTTTACATGTAAAACCACTTCTTCGACGCAAATGCTTCCCTCATCACTGGGTCCAAAGTTCCATGCTTCTGCAAATTCAACTCGTTCTTCAAGCAGTTTTTGCCCGACCTGTAAATAGCCACTGAGTGGTTCAAGGACATGTTGCCACGGTCTGGTCGCTTTTGGGTTTCGGATACTTACTTTTTTACCTTGACTGACGGAGAGCATAATATCGCTCATCAATCTATCTTGCGCCCAGTCTCCACCACCAATGACATTTCCAGCTCGACAAGTTGCTAAAAGCGTTTGATGCGATTTTTTGTAGTCGTTTGTATTAAAATAAGAATTGCGATATGAAGTTGCGAGTAAATCTGCACATCCTTTTGAAGCGCTGTAAGGGTCATACCCGCCCATTGGGTCATTCTCTCGGTATCCCCAAATCCACTCTTTATTTTCATAGGCTTTATCACTGGTGATGTTGACAATGGCTTTCACCTGATGTTTGCGACATGCCTCAAAAACTTTAAGGGTACCCATGACATTGGTTTCATAGGTTTCGATAGGATTGGCATAAGAAGGTCTGACCAACGCTTGAGCAGCCAAATGAAAAACAATATCTGGCTTATAGGTTGCAAAAGTTTTATCTAACGTTTCTAAGTCTCGTATATCACCGATGATCGACGCGATATCAAGATCAAGCAATGCTAAATGATTGGGGTGGGTGGGAGCTTCCAAAGAATAGCCCACGACCTTAGCACCCATCTGCTTGAGCCAATACACAAGCCATGAGCCTTTAAAGCCTGTATGTCCTGTGACTAAGACAGTTTTATCTTTGTAGATACCACCAAAAAGATGTTGCATTACCAAACTTTCCATGGCGCTTTGTTCTCTTTCCAGAGTTTATTGAGTTTTTGGTTATCACGAAGTGTATCCATGGGTTGCCAAAAACCATCATGTTTATAAGCAAACATTTCACCATCTTTGGCTAAATTTTGTAAGGGAGCTTGTTCAAAAATACAATTTTCATCTTCAATAAGATAATCAAATACTTTAGGTTCACATACAAAAAAGCCACCATTAACCCAACCCGCTTCTGTCTTTGGTTTCTCTATAAAACTGTTAATATTCATCGTTTCATCAATATCAAGATTACCAAACCGCGCCTCTGGCTGAATTGCAGACATTGTAAGCGCTTTTCCATGCTTTTGATGAAAGGCTACCGTTTTTGCAATATCAATATCACTCACGCCATCTCCATAGGTCAATAAAAAAGACTCGTCTCCTATATACTTTTGAGCACGCTTAATACGACCTCCGGTCATCGTATCAAGGCCGGTATCCACAAGGGTGACTTTCCATGGCTCACTGGTATTATTATGCACTTCCATGCTATTAGTTTGAAGATCAATGGTTATATCACTTTGGTGCAAAAAATAATTTGCAAAATACTCTTTAATGTAATAGCCTTTATAACCAAGAAGCACGACAAATTCATTAAAACCATAATGGGAATAGATCTTCATAATATGCCATAAAATTGGCTTGCCACCAATTTCCACCATCGGTTTTGGTTTTATATCGGTCTCTTCTGCTATTCGTGTTCCATATCCACCTGCGAGTAATACGACTTTCATTGTATCTCCATAAATAACTTATTCATTATTAACGTTTATTTTATACAAACATTCTTCCAAACTATCTTTCCAGTAAGAAATTTCTATGCCAAACTCATTTTTGATTTTTGATTTGTTTAAAAGAGAGTAGTGAGGCCTTGTTGCAGGTGTTGGGTACTGCGATGTTTCAATAGGATTGATTTTACATGTAAGCTTTGCCATCTGCATAATCTCTCGTGCAAAATCATACCAACTGGCAACACCTTCATTAGAATAATTATAAATCTCCGTTTGGGTATTTTTGATTCTTGGCAGAATATCTAAAATCACTTTCGCTAAATCTTTTGCATAAGTAGGACTCCCTACTTGATCGTAAATAACACCCAAAGAGTCTTTTTCTTTACCTAAACGAAGCATCGTTTTGACGAAGTTAGCACCATGACTACTGTAAACCCACGATGTTCGAATAATGACGCTATTGGGGAGCTTACCATGTAAAAGCGCATTCTCTCCACCCAACTTCGTTTTACCATAAACCGATTGAGGATTGGTCTTATCTGTTTCGCCATAAGGTTTATGATTAGTTCCATCAAAAACATAATCCGTTGAGATATGAATCAGTTTGATATGCTTTTCTTTTGCAATGCTTGCTAAATGCTCTACTGCTTGATGATTGATTTTATCGGCTAAAGCTTCTTCACTTTCAGCTTTATCGACTGCGGTATAAGCCGCACAGTTAATAATGGCATGAATAGTATTTTTTTCAACAAATGATTCAATAATGTGTTTATCCGTAATATCAAGTTGATCTTTACATGTAAAGAAAAATGTATAGGGGAAATGGGGAGAAAGTGCTTGTATCTCGCTTCCTAATTGACCGTTTGCACCTGTCACTAAGATATTAAGCATAGTAATTTACGCCATATTCAAAAAGGTCATTGGTCTCTGCAAGTTTAGGTTGCTTGGTATCTTTTGCGGAGAGTTGAAACAAATCTGCACTCATTTGCCAATCAATACCCAGTTTTGGATCATTAAATGAAATTCCTCGGTCACACTCAGGGGCATAGTAGTTATCGACTTTATAGGTAAAGGTACAGGTTTCACTCAGCACTACAAAACCATGAGCAAAGCCTCTTGGAATAAACATCTGTTTTTTATTTTTTCCATTAAGTTCTACAGCTACATACTTTCCAAATGTGGGACTCCCTACACGAATATCTACAGCAACATCCAGAACTCGTCCATCAATGACACGAACTAATTTTGATTGGGCAAAAGGTGCAAGTTGATAATGAAGTCCACGCAAAACACCATGATGACTTCGTGATTCATTATCTTGACAAAAATTCACTTTGAAACCTACAAATGCTTCAAACATATCTTGTCTAAAGGTCTCTACAAAGTACCCTCGCTCATCACCATGTACTTTGGGCTCTATTATGATCACGTCTGGTATAGAGGTAGGCGTAAATATCATCTCTTACTTCTTTCTTGTGTCATTTTTTATTTTTATATCTCTTCTTTTATTCTCATATAGATAGGAAACCGTGGTTTACCGCCTTTAGTCATCTCTTGAAATTTATAAGTAATCTTTGCACCAATGGCAGGAGGATTTTTACGTTCCGCATCACTAAAGCCTGAACCGATGTCAAACATCACGCCATCATCCGTTTTACATGTAAGCGAACCAAAGCTATTTTTGTACTTGCCTTCGCCTTTGTGATGCTCCACCACTTCACACTCTGCATCTTGAAAACTTTTCACTTTCAGGCTATTAGGATCACGCTTAACGACATATTTGGTATCGGGATTGCGCACGACAACACCCTCTCCACCGCCTTTTTCAACTTCTGTAAGAAAACGTTTCAGATCATCATTGTCTTTACATGTAAACTGTTTTGCCACTTTGAGGTAGTCGGCTTGATTGAGTTTAAGATAATACTCCAACTTTACTAAACGCTGGATCAAACCACCATTTTCATTCGGCACATCAAAGGCGTAAAAAGCGATGTTTTTCCATCCATCATGCGGCTCTTTTTTCTTCACAATAGAGATAATAGTTTCAAAATCACCCCGTTTACTCCAAAGCTCTCCATCCACAGCAAAAGGAGGAAATCCTTCGGTAAACCAAGCAGGAGCCGCAAGTTCAACGCCACCGCGTGAGATCAGTTTTTGCCCATCCCAGTACGCCCGCACTCCATCCATTTTTTCACTCATGAGCCACCCTGAAACGTCTTGTCCATCCCATTCTTGTAACAACATCAATTCAGGCTTAGCTCCAAACATTAAACTTGTTAACAGGAGCCAAGAGAGCATTAATCGCTTCATTTATGCCTCTGTTGTGTATTTTCTCAAATACCACTGAATCGTTTTAAGAATGCCGCTTTCAAAGTTTTCTTCTGCTTCCCAACCTAGTTTTGTCTCAATTTTGGTGGCATCAATGGCGTAACGTCTATCATGCCCTGCTCTATCTTCCACAAAGGTAATCTGCTCTTTATACGAAGTGGCTTTTGGTTTTAGGGTATCGAGTATCTCACAAATCTTATGAGCGATATAAAGGTTATCTCGCTCATTGCGTCCACCAATATTATAGGTTTCTCCTGAGTTTCCTTCATGGAAGACCAAATCAATGCCTTTGCAGTGATCTAGCACATAGAGCCAATCACGGATATTTTTTCCATCACCGTAAATGGGGATTTTTTGATTGGACAATGCTTTGCGTATGATCGTAGGAATCAGTTTTTCATCGTGTTGTTTAGGTCCATAGTTGTTGGAACAGTTGGTGATGACCGTATTCATTCCATACGTATGATGATAGGCGCGTACGATCATATCACTGCTTGCTTTGGAAGCTGAATAGGGAGAGTTGGGTGCATAGCTTGTGTTTTCTGTAAAAAGTCCCGTAGCGCCAAGCGTTCCATAGACTTCATCGGTTGAGATATGATGGAAACGACACTCCTCATAGCCCTCTTTGAAGATGAAAGGTTTTTCCATCCAGGTTTTATACGCCACATCAATGAGCGTAAAGGTTCCATTGACATTGGTTTCGATGAACACGCCTGGGTTTTTGATGGAGTTATCCACATGCGACTCTGCTGCAAAGTGAATCACGCCTTGGATATCATATTTTTCAAACAGAGACTCGACTAGAGCCCTATCACAAATATCCCCTTGTACAAAAGTATAACGATCACTTTTTTCTACCTCTTTGAGGTTATCTAAATTACCAGCATAGGTTAAAAGATCCAAATTGATCAGATGGTACTCTGAATACTTTTCCAAAAAATACGGTACAAAGTTAGACCCAATAAACCCTGCACAACCGGTGACTAAAATACATTTTTGACTCATTTAACCAATTCCTTGAGGTATTCTCCATAACCGTTTTTACTCAGAGGTTTTGCAATCTCCAAGACTTGCTCTTTGGTAATCCAGCCATAATTATAAGCGATCTCCTCCAAGCAAGCAATTTTAAAACTCTGTCGCTTTTCAATCGTTTGCACAAACATGCCAGCTTCCAATAAACTGTCATGTGTTCCCGTATCAAGCCAAGCAAAACCACGTCCTAAAACTTCAACTTGTAAATCGCCTCGTTTAAGATAGGCTTCATTTACAGAAGTGATTTCAAGCTCACCTCGATCACTTGGTTTAACCGCTTTGGCGATCTCAATCACACTGTTATCGTAGAAATAAAGTCCCGTTACGGCAAAAGGTGATTTGGGGTTTTTAGGTTTTTCTTCAATGCTGATTGCTTTTTGATTTTCATCAAACTCGACGACACCAAAACGTTGTGGGTCTTTGACCTGATACCCAAAAACAATCGCTCCCGATTTTAATTGAGCCGAGCTTTGAAGCAGTGGTGTAAAGCCTTGACCGTAAAAAATATTATCTCCCAAGATCAAACAAACGCTATCATCGCCGATAAACTCTTCACCTAAAAGAAACGCTTGTGCCAATCCATCAGGACTGGGTTGAATTTTATACGAGAGTGAAATTCCCCAATGAGAGCCATCGCCAAAAAGATCTTCAAATTTGCCAATATCTTGAGGGGTTGAGATAATCAAGATCTCACGAATTCCAGCTAGCATCAAAACAGAGAGCGGATAATAGATCATTGGTTTATCATAAATCGGCAACAACTGTTTGCTAATCGTTTGGGTAACAGGATAAAGTCTGGTTCCAGACCCTCCTGCTAGGATGATGCCTTTCATGTTAGTGAAGCTCTGCTTTAGCGTACGCGATCAGTTCGTTCAGTTTTTTCTCGTACAATTTCGCGTTATCCGCATTGGTCGATTCAAAACGTGTGACTAAAACGGGTGTTGTATTGCTCGCTCGCACCAAGCCCCAACCATCGTTAAAAATGACTCTTACGCCGTCAACATCAACAATCTCTTTAATAGCAGGAAAATCTTTAGGAGGATTTTTCAAAAGCTCTTTGACTTTTTCAACAAGAGGAAACTTATCGCTTTCATTGGTCTCAACTTTAAGTTCTTCAGTAGAATAAACGGTTGGTAATTTTGCGATCTCAGCATCCACATCCAAACCATTTTTAACCATTTCAATCATACGAAGCGTGGCGTAAATCGCATCATCGTAACCAAAATAACGGTCATTAAAGAAAAGATGTCCGCTCACTTCCGCTGCAAAATCGGCGTTCGTTTTAGCGATCATCACTTTAAGGTTACTGTGACCTGTTTTATACATAATCGCATGACCTCGTTTGTTAATCTCATCGTACATCACTTGAGAACATTTCACTTCACCAATGACCGTTGGGTTTTTCATAGCGCTGGAAAACAAAATCGCCATAATGTCGCCTTTGACATTGTTGTGCTTGGTCAAAAACGCCAATCTATCGGCATCCCCATCATACGCAAACCCAAGCGCATACTCGCCTTCAAGCTCTTTTTTAATGTCTTTGAGGTTTTTCTCAACGGTTGGGTCAGGATGGTGGTTAGGAAATGTACCATCGGGGTCTGTAAATAAACCTTTACATGTAAAACCTAAAGCTTTAAATACATCTTGCACCACAACGCCTGCAACGCCGTTTCCACAGTCATAAACAAACGGTTGCTTGAAGCCTTTAAGGTGGTCAAACTCTTTGATCAAAAAGGCGATATAACGCTCTTTCGCATTAATAAACGTTGAGCTTAAGTCATCTTCGATTTCCATCGCGTAATTTTGCATAATCTCGCGACCCAGTGCGTAAATGTCTTCGCCAAAAAAAGGCTTTTTATCGAGGGTTACTTTAAAACCATTGTATTCACTAGGATTGTGAGAACCCGTGATCATAATGGAAGCATTAGGTGTTACGCCATCGAAATTTTGAAAATTACTAAAGTAATTCACCGGTGTCGCAACGAGTCCCATGTTAAGCACGTTACAGCCAGCTTTGTTGAGTCCGCTAGTAAGATACTCACACAAAATCGGTGAATGTGAACGCGCGTCATACCCTATCGCAACATTTTTACCCACTTTAGCAATCTGTTTTCCTAAAAAATACCCAATAAGTTTAACCGTTTGCTCGTTCAGCTCTTTTTCGTAAATACCTCTGATGTCATACTCTCTAAATATCGCTTTCAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP045453|751343:762782|760546_761410_-|WP_167749443.1|DBSCAN-SWA
MKGIILAGGSGTRLYPVTQTISKQLLPIYDKPMIYYPLSVLMLAGIREILIISTPQDIGKFEDLFGDGSHWGISLSYKIQPSPDGLAQAFLLGEEFIGDDSVCLILGDNIFYGQGFTPLLQSSAQLKSGAIVFGYQVKDPQRFGVVEFDENQKAISIEEKPKNPKSPFAVTGLYFYDNSVIEIAKAVKPSDRGELEITSVNEAYLKRGDLQVEVLGRGFAWLDTGTHDSLLEAGMFVQTIEKRQSFKIACLEEIAYNYGWITKEQVLEIAKPLSKNGYGEYLKELVK
>NZ_CP045453|751343:762782|757238_758108_-|WP_096047223.1|DBSCAN-SWA
MLNILVTGANGQLGSEIQALSPHFPYTFFFTCKDQLDITDKHIIESFVEKNTIHAIINCAAYTAVDKAESEEALADKINHQAVEHLASIAKEKHIKLIHISTDYVFDGTNHKPYGETDKTNPQSVYGKTKLGGENALLHGKLPNSVIIRTSWVYSSHGANFVKTMLRLGKEKDSLGVIYDQVGSPTYAKDLAKVILDILPRIKNTQTEIYNYSNEGVASWYDFAREIMQMAKLTCKINPIETSQYPTPATRPHYSLLNKSKIKNEFGIEISYWKDSLEECLYKINVNNE
>NZ_CP045453|751343:762782|751343_752681_-|WP_167749440.1|DBSCAN-SWA
MSKEEQLKQEILEKTKQYYELVHKKNQTRPFVAGESRVNYAGRVFDEKEMMNLVDSSLDFWLTYGDYSKKFEKELAKFLHVRWAFLVNSGSSANLLAFYALTSPLLKERQVKRGDEVITVAAGFPTTVAPIVQYGAVPVFVDMELTHFNIDVTQLEQALSSKTKAVMIAHTLGNPFNIKVVKAFCDKHNLWLIEDNCDALGSTYEGKPTGTWGDIGTSSFYPPHHMTMGEGGATYTDNPLLKKIMLSMRDWGRDCWCESGVDNTCGCRFTQQFGSLPKGYDHKYVYSHFGFNLKVSDMQAAVGCAQLEKFPSFVEKRKVNFKKLYNGFKDVPELILVEAQPQSDPSWFGFMMTIKDNVKFSRNELVEYLENNNIQTRNLFAGNMLRHPLFESLEKDKDYRVIGLLPNTDKIMSDSFWIGLYPGMSDDAIGYMIEKIVYFIRSQTN
>NZ_CP045453|751343:762782|752680_753601_-|WP_167750851.1|DBSCAN-SWA
MNIFITGSSGFIGSHLKEYLLGHHHDTLFIPSSKELDLSDEKAVDRYILENKIDVIVHTANRGGGRDTADMKNVTEYNLRIFFNIAKHEKNVKKIISFGSGAEYSKQKPIIEAKEDDYLQALPLDEYGFYKSITSHFIEKSENIVQLRIFGAYGEYENYRYKFISNAIVKNLLHLPITINKNVYFDYIYSDDLVKIIDFFIYNDTKEKIYNVTTGTKVDLITLANLVNEVGDFYSDIRVIHEGLNNEYTSNNERLLKEFGDFQFTSHKNAIAKMRCYFQENLDKLDIQTIKEDPYLKAIDTMWKGK
>NZ_CP045453|751343:762782|755349_756447_-|WP_167750624.1|DBSCAN-SWA
MQHLFGGIYKDKTVLVTGHTGFKGSWLVYWLKQMGAKVVGYSLEAPTHPNHLALLDLDIASIIGDIRDLETLDKTFATYKPDIVFHLAAQALVRPSYANPIETYETNVMGTLKVFEACRKHQVKAIVNITSDKAYENKEWIWGYRENDPMGGYDPYSASKGCADLLATSYRNSYFNTNDYKKSHQTLLATCRAGNVIGGGDWAQDRLMSDIMLSVSQGKKVSIRNPKATRPWQHVLEPLSGYLQVGQKLLEERVEFAEAWNFGPSDEGSICVEEVVLHVKKHWDAIAYEINRDPNQLHEANLLKLDCSKAHIKLHWKDVWDSEDTFEKTVKWYKAFYETHEILSQKDLENYIVDAKEKNIAWTIK
>NZ_CP045453|751343:762782|758708_759527_-|WP_167749441.1|DBSCAN-SWA
MKRLMLSWLLLTSLMFGAKPELMLLQEWDGQDVSGWLMSEKMDGVRAYWDGQKLISRGGVELAAPAWFTEGFPPFAVDGELWSKRGDFETIISIVKKKEPHDGWKNIAFYAFDVPNENGGLIQRLVKLEYYLKLNQADYLKVAKQFTCKDNDDLKRFLTEVEKGGGEGVVVRNPDTKYVVKRDPNSLKVKSFQDAECEVVEHHKGEGKYKNSFGSLTCKTDDGVMFDIGSGFSDAERKNPPAIGAKITYKFQEMTKGGKPRFPIYMRIKEEI
>NZ_CP045453|751343:762782|761411_762782_-|WP_096047228.1|DBSCAN-SWA
MKAIFREYDIRGIYEKELNEQTVKLIGYFLGKQIAKVGKNVAIGYDARSHSPILCEYLTSGLNKAGCNVLNMGLVATPVNYFSNFQNFDGVTPNASIMITGSHNPSEYNGFKVTLDKKPFFGEDIYALGREIMQNYAMEIEDDLSSTFINAKERYIAFLIKEFDHLKGFKQPFVYDCGNGVAGVVVQDVFKALGFTCKGLFTDPDGTFPNHHPDPTVEKNLKDIKKELEGEYALGFAYDGDADRLAFLTKHNNVKGDIMAILFSSAMKNPTVIGEVKCSQVMYDEINKRGHAIMYKTGHSNLKVMIAKTNADFAAEVSGHLFFNDRYFGYDDAIYATLRMIEMVKNGLDVDAEIAKLPTVYSTEELKVETNESDKFPLVEKVKELLKNPPKDFPAIKEIVDVDGVRVIFNDGWGLVRASNTTPVLVTRFESTNADNAKLYEKKLNELIAYAKAELH
>NZ_CP045453|751343:762782|758100_758676_-|WP_096047224.1|DBSCAN-SWA
MIFTPTSIPDVIIIEPKVHGDERGYFVETFRQDMFEAFVGFKVNFCQDNESRSHHGVLRGLHYQLAPFAQSKLVRVIDGRVLDVAVDIRVGSPTFGKYVAVELNGKNKKQMFIPRGFAHGFVVLSETCTFTYKVDNYYAPECDRGISFNDPKLGIDWQMSADLFQLSAKDTKQPKLAETNDLFEYGVNYYA
>NZ_CP045453|751343:762782|753604_755353_-|WP_096047221.1|DBSCAN-SWA
MKASDYIVQFLVDQGIDKAFGYIGGAVAHLYDSFDKNTGIEIVNTIHEQGAGFAAEGYARVSGKTGVATATSGPGATNLITPIGSCFFDSISTLFITGQVNTYEYKYDTPVRQIGFQETDIVSIVKPITKYAVMIDMIQNLRYELEKAYFLTQNGRKGPVLIDIPMNIQRTDFNPSEQKSFFESDEYKMMRIQGDKIDFEKIVEMLRVSQRPIILVGGGSRLSSLAPEAIHRLLEKSNLPVVYSLMGKDVVKDDYKYNFGLIGSYGNRYSNLALANADLIIVLGSRLDTRQTGTDLKTFARAAKIIHVDIDVNELDSKIKADVTLHCDIADFINTLSHYDFKLNLGQWLEKLVTYKQNYSSTTGIDGKAKVPNQIIQWIAQSSSDHDMICVDVGQHQMWVAQSFETKADQRVLFSGGMGAMGFALPTAIGATIGTKKRALVIVGDGGFQMNIQELEVIKRRNLPIKVFIMNNANLGMVRQFQEIYFEQRYIGTQKDYSVPNFASIANAYGLKSSTISTIEEISQKIHETLLSDEAEIINICLQEQMTTVEPKLIVNKPIEDMYPFLEREEFNAQMIIKPLEH
>NZ_CP045453|751343:762782|759527_760550_-|WP_167749442.1|DBSCAN-SWA
MSQKCILVTGCAGFIGSNFVPYFLEKYSEYHLINLDLLTYAGNLDNLKEVEKSDRYTFVQGDICDRALVESLFEKYDIQGVIHFAAESHVDNSIKNPGVFIETNVNGTFTLIDVAYKTWMEKPFIFKEGYEECRFHHISTDEVYGTLGATGLFTENTSYAPNSPYSASKASSDMIVRAYHHTYGMNTVITNCSNNYGPKQHDEKLIPTIIRKALSNQKIPIYGDGKNIRDWLYVLDHCKGIDLVFHEGNSGETYNIGGRNERDNLYIAHKICEILDTLKPKATSYKEQITFVEDRAGHDRRYAIDATKIETKLGWEAEENFESGILKTIQWYLRKYTTEA
>NZ_CP045453|751343:762782|756446_757220_-|WP_096047222.1|DBSCAN-SWA
MKVVLLAGGYGTRIAEETDIKPKPMVEIGGKPILWHIMKIYSHYGFNEFVVLLGYKGYYIKEYFANYFLHQSDITIDLQTNSMEVHNNTSEPWKVTLVDTGLDTMTGGRIKRAQKYIGDESFLLTYGDGVSDIDIAKTVAFHQKHGKALTMSAIQPEARFGNLDIDETMNINSFIEKPKTEAGWVNGGFFVCEPKVFDYLIEDENCIFEQAPLQNLAKDGEMFAYKHDGFWQPMDTLRDNQKLNKLWKENKAPWKVW

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_167749440.1|751343_752681_-	lipopolysaccharide biosynthesis protein RfbH	A0A218MN59	uncultured_virus	9.3e-68	35.3
WP_167750851.1|752680_753601_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_096047221.1|753604_755353_-	thiamine pyrophosphate-binding protein	E4WLQ6	Ostreococcus_tauri_virus	1.2e-83	34.0
WP_167750624.1|755349_756447_-	CDP-glucose 4,6-dehydratase	J7Q7J8	Aeropyrum_coil-shaped_virus	5.5e-18	27.9
WP_096047222.1|756446_757220_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_096047223.1|757238_758108_-	dTDP-4-dehydrorhamnose reductase	A0A1D7XFA3	Escherichia_phage	2.9e-38	36.8
WP_096047224.1|758100_758676_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.6e-43	50.3
WP_167749441.1|758708_759527_-	DNA ligase	A0A1X9VNU1	Mimivirus	6.3e-35	35.2
WP_167749442.1|759527_760550_-	dTDP-glucose 4,6-dehydratase	K7QJG5	Escherichia_phage	1.2e-78	46.1
WP_167749443.1|760546_761410_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.7e-105	65.6
WP_096047228.1|761411_762782_-	phosphomannomutase/phosphoglucomutase	A0A127AWJ1	Bacillus_phage	9.8e-57	32.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP045453|873879:881531|DBSCAN-SWA
GTCACCTACCTTTCGCGTAGGTCTCCCATCCTGCTTTTCGTAGCACACATGCAGGACATTCGCCACAACCATAGCCCCATGCATGCTTTTTATCGTGGACACCATTATAGCATGTATGTGACTCATCGATGACGAGTTCTAAGACACCCTCTTGGTGTGAAAGTTCAAAGGTTTCAGCTTTTGTGAGGTGCATAAGCGGGTAATGGAAAGTGATGTTGGCTTCGCTTCCAAGATTAAGGGCAAGTTCAAGCGCCTTTACAAAAGGCTCTCTACAATCAGGATACCCTGAATAATCGGTCTGATTGACTCCAATGATGATATGCTCAATACCTTGTTTTTGCGCAAATGCGTGCGCAAGTGTAAAAAAGATCGCGTTGCGATTGGGAACAAAGGAAGCAGGGAGATTGGTATGCGTTCTATGATGTGCGCCAATATCTTGCGTACCATCAATTAAAGCCGAATCATTCAGTTGTGAAAAGGCATCTAAGCTGAGCAGTGTATTTTTTACATGTAACGCTTTGGCGATCTTCTCAGCTTGCGCAATTTCCACGCGATGCTTTTGGCCATAATCAAACGTAATGCTTTCAACACTATCAAAACGATTCTTTGCCCAACCCAGACAAGTCGTACTGTCTTGTCCACCACTAAAGACCACTAATGCTTTGGAAGCAATTTTTCCCATTATTCCACTCCTAAAAACTTGTGCAACTGCACACTCAAGATAAATTGTGGATGTTCTTTGACAAACTCCACACAAAAAGCAACATTTTCTTTGTTGGGTCGATCCATCTCATTTTGAGGCTGAATGAAGATGGGTTTGTAGCTTGAAAATTCAAGTATTTTTTCAACTGCAGACTCTTTGCTCACCACAAATTTAATCTCATCGTAGCCATATTTTTCAATTTTATCCCAATCTTTTGGGCTATAGGTCACCCAGTTAGCACTCGCAATGTTGGAAAAATTATAGCCATTCGTTTCGACAGAAACAGCATACATATACGCTTGCAAATAATCAATAAAACCATTAAGATTATAAATACTCGGCTCGCCACCTGTAATGATGACATTCATGGCAGGATAAGGCTTAATACGTGTTAACACCTCATCAAAACTAAGACTTTCATATTCTCCTTTGTGCAAGAACTCATCACAAAAGGAACAGGTGAGATTGCACCCATACAGTCGAATAAAAATAGAAGGAACGCCCACATGTGCACCTTCTCCTTGAATAGAATAAAATATATCGACGACTTTTAGCATGCCACCCTTTTCCTTAATAATGTTTCAAAACATTATTATCTATTGTGTAACATTATAATATGAAATGGATTAGAAGATTATTTGAAAAAGTGCCTCTTGTTTTAAGATTAACAAGAGGCGTGTAGGTTTACATGTAAGCTTTTTAGTGATGTGATTTGATAATTAGAATGGTCATTCGGATGTTGATCATAATAAATTTTATCACTTGCCAAATCACACAGGTTCTTCTAAAAAGTGTAAACTTTGAAGGAATCGGTGTAAAAGCATTTTGTGAATACGGTGTTAATTTCATACTATTCTCCTTTGTTTTCATTTTTTGTCACGCCTTTAGAGCAAAGCTCTAAAGACTACGTTAACACTGAGTTTTGCTTGGCGCAATGCCCGTGCATCTTCGATGCTTTTAAGTTCTTATGGAACTTTGTCTCGCACTCAAAGCAAAGCTTCTCATGCTACGCTAACGCACTTTATTCTGGGATAATGGACCAAAAAGGTTTCATTTTGGCTTTCCAGATAAATGCATGGTGTAAAAGATGCTTAACCCAATGGGCAGCAAGACCAATTTCACCAAAAGTACCGCCAAAATCTCTACCATAATCAGGATATTTTTTATAATTCGGAATAATCGGATACATGGTCATCGCAACAGCGGTTCCTGAGAACAACCCTTTACCAGCACTCGCAACACACGCTGCACCCATTTCCGCCATACACGCGGTATGGGTTGGTGCACTCGCACCCCCTATCATATCAACGATGCTTGCAGCAACCGCTTTTCCCATCATCGCACTAGGCATTCCTGTTCGTGGAGGTGTTGGATTGATCGGTGTGCCATTAGGAGATTTCATCGGTTTAGAGATGATATGCGGTGGTGCAAAGGCAATACCTGCCGCAAAAATATTTTTATATTTAGGATTTTGACATGTTTTTGGCCAATCAGACGCATCCCATGTTTCATACGGAGCTGTTGCTTTTGAGTAATCCCCATCAACAAACATAAAACCACCCGCATTGAACATAGAAGAGGTAATGTCTTCTCCATTTTTATCGTATGCTTTCATACCAGCCCCTGCAAATGGAGGAATGAGCATAGAAAAGTCATACGTCTCTTCTTTCATTTCGCCTGCAAGATTTTCGTAATGGACTTTGTCTTTTTCAACTTTATTGACATGCGCTCTCGTGATCCATTTGACATCACGCTCGGCGTATAAAGATTCTGCAAAGACTTTGCCACTGGTGATGTAACCACCCATTTTAAGGTGCATACCGCCTACACCAAAGTCACCGAGTTCATATTCATTAGAGATATAAGTGATGGTCGCTTTGTCACGAACACCCTCAGCACGCAAGCGATGATCGACGTTAAACGTGTACTCAAACGCTGCACCTTGGCAGGTACACATTCCATGACCTGTACCAATCAAAATCTTTTTCTCTTCACCTTTTTTTAATGCTTCGATAATCTTTTCAAGCTCATCTGCGGCATGTTTAGCATGTGAAGCCGTACAAACGGAAACAGTAAAGCCATTGTCCGGTCCTAAACCTTCTGTTGCTGCAAAATTGAGCCGTGGTCCTGTGGCATTGATGAGATAATCATACGTGATTTCCTCTTTTTCGCCCTCTTTATTTGCACCAGTGTGTTCTATGGTAACAAAATTTTTACTATTTTCCACTGTGCCCTCAGGGTGAATAGTAAGTGCTTTTGCTTGAATATAGGTAATGCCCGCTTTTGCATAAATGGGTGCCAAATCAAACAGAACTTCCTCTTGATCCATTTGACCAACACCTACCCAAATGTTCGATGGAATCCAATTCCATTTGCTATTAGGGGTTACAACCACAACTTCATGAGTTCGATTGAGCCATTTTCGCGCAAACTGTGCGGCGGTATGCCCTGCAACACCACCACCCAAAATAACAACTTTAGCCATCAATTATCCTTATAAAAAATGTAAAACTTTTTGATTGTATAACAAGAAAAGATAAAATAAAATTGTACTATTACAAATCCGAAGTTATTTAAGGTTTAAAAAAGGTTTACTTTTTTTGACAGCTATATTTTGGTATCATTCCTAAGATATTTTTCGATGTAAAAGGGTATAACCAATGTTATGGCAAATCAGTAAAGAATTCGATTTTTGTTATGGGCACCGCGTTTGGTCACAAGAGCTGGATGCTGAATTTTCCCTCAGTGGGTGCTTAGCGTGCCGTCACTTGCATGGACATCAAGGCAAAATTATCGTTTTTTTACAAAGTAATGAACTCAAAAATGGTATGGTGACAGACTTTCATCATCTGAACTGGTTTAAACTCTTTTTAGACAATACCTTAGATCATAAATTCATCATTGACATTCACGACCCACTCTTTGCGACCTTATTGCCTCATTTTGCTGACAAACAGAATTTACTTTCCCATGAAAGTGGTTATAAAACACCCGATCTCTCTTTTATAGCGCATGAGCCAAATTATCTTGTAGAAATGTATGAGGGGTATATTATCGTTGATTTTGTGCCAACCAGTGAGAACATCTCAACGTGGCTGCTTCAAATCATTGCGAAAAAGATGAGTCGCTTGGGAGTGGAAGTCTCGCATGTAGAATTTTTAGAAACCCCAAAAAGCCGAAGTATCGTTTACAACCATTAGCGTTCTACCCGAACGCTGAACGTAGCCTCTAGAGCAAAGCTCTAAAGACTACGTTAACACTGGGTTTTCTTTGAAGTCAAGCCCGCGCACTTTCAGTGCTTTTAAGCCTTTGGATAGACCTTTTCGAGTTTTTTATAGAGCGCATCCACAGTGGGAGCAGACTCGCCATGAAGCAATGAAAGCATCACTTCGTTATCTTCTTTACCATTCCACACTTTGATGTAATGTCCCTCTTTGTAGCCATGATCTTGGCGGAATTGGTTAAGCACGTTTTTAGCCACATAGAATTTGTACAGCACTTTAAGGTTGATGCCACATTTTCTTGAAAGTGTAAAATACTCTTTCAACAGTCCATCAAAAAGATCCATTTCAAAACCTGTCGTATCGTGAATGATGCTCTCGATGTCATTGACCAGTTCCATTGGTACAGCCATACCGATAGAGAGTGGTTCTTTGGTAAATGCTTCAAATCCCTGAACATCCAACACATCTAAAACAAGTTGTTCAATATCGCCTCTGTTGTTCGTTTTATAATCTTCCAATAACAGGCTCATAATAAAATGCCAAATATCAACGATTTCAACGGTGACATTGTCCCAATCGGTCGGTTTATTAATGTTTTTCCAATGTTTCCAACTAAAACTATCAATGAGTTCCGCACACTCCATATAAATACATCGCTTCCAGTTAATCATGCGGTTATGTTTGGTATAGCCATTTTCCCAGCCAATACCATTGGTTTCGTCGTTCAGTTTTTGCTGTAACGCAAACATTTGCGTTAAATAATCTTTACTTGTCATTCTATTCCTTCGATCTTAAAAGGGTTTCATTATACTTTTTTGCGCCATAAAAGTCAAAATGGATTCACTGCCTTTGCGATATCCAAGCTCAAAACAAGCATCTATTTGTCTAAAAGTAAACAATCCAAAATCATTGAGTGTGGGATCGCTAATGCACAGATCACTCTGCTCTATCTGCTGTTTCGATGAAGCCAAAATGGAGAGATAAATAGCGCGCTCAAAACTGGAAAAAAAGTTACTTTTTTGCTTTACATGTAAAGGAAACAAATTAACACTCACCACAGGATAAGGAAGCTCTAAAAGTGGTGCTACAGGCAGGTTATCCATAAAACCACCATCAATAAGCGTGTAATTATCATAAGTGATGGGGCGAAAGATAGGAATGAGCGCGGAGCTTGCGATGGCAAGGTTAATTGTATTGCCATGGCTAAAGCGGACGATTTCGCCATGAGGGAGATCAACACATGTCATAAAAGTAGGAATGCTCATCTGCTCTAAACGCTCAATAGGGGCGATCTCTTTCAGAATAGCTGCTTTTTCATTGATGCGAAGAAGTCCCTTGCGAAAATAGTTAAAATGAAACACTTTGCGAAAGGCTCTGCTTTTAACGATACGCAACAGATCAAAAGCACTGACACCTGAACCCACACCGGCGGCAATCACCGAACCAATGCTACAGCCTGAAACAGCGGCTATCTCCACATTGTTTCGCTCCATTGCAGCAATGACACCCAGATGAAATGCCCCCCTTGCCGCACCGCCCGAAAGGGCTAAGGATATTTTCAATGTCCCAGCCATCGTATAATCCTAAATTCACCCTCTAAGGTTTCGACTATTGCGGTGCAAGACTCAACCCAATCGCCACAATTCAGGTACTTAATCCCCTCAATATCGCGAATCTCCGCCTTATGAATATGCCCGCAAATCACCCCATCGTAGTTATTGCGTTTGGCATGCTCGCTGAGAATATGCTCAAAATCGGTGATAAAAGAGATGGAGCTTTTGACATTGTCTTTGACGTATTTGGAGAGTGACCAGTGGCTGTGATAGCGCATTTTCTTGCGAAACCAACCAATAAGTTGGTTAACATTGAGCAAAAGGTCGTACCCCAAATCACCCAAGATGGCAAGCCACCGTTTGGTCATCGTAACCGAGTCAAAAAAGTCACCGTGCGTAATGAAAAATCGCTCGTTGTTGAGACTTGTATAATCCACTTCATCGACAACCGCGATGCGATCGCCCAACCCTAACGGCAAAAAGGAACGTAAAAAGTCATCGTGATTGCCGGTGATGTAAAAAACATTCGTCCCTTTTCGGGCTTTTCGTAAAATCTTTTGAATCACATCGGAGTGCGACTGTGCCCATTTGATTTTACGCTTAATCGCCCAACCATCGATCACGTCACCCACTAAATAGAGATTTTCACTGTTTGTAAATTTTAAAAAATCCAAAAGCTCCTCCGCTTGTGAGAAACGCGTTCCCAAGTGAAGGTCGGAGATAAAGATCGAGCGAAAGGCTATCGGGTCTTCATCCCCTGAAAATTCGTATTTGGTCATTTGTGTTTGTCGCCGTCCCCAAAAATATCATCCGCAAAGTGTGAGAACTTACCTCGTACCGATTTATCCAACTCTATCGCAAAGAGTGAGATGTGTGTCTGCTCTTTTTTGGTCTGTTTGAGCAGTGAGGTCAAACCGTTGTTAAAGCGGTTTAAGTACATGTTATCAATCTGTCGGTTTGAGCCAATCACAATCGCTTTACAGTTATTATCCAGACGGGACAAGATGAGCTGCGTGGTATTGTTGGAGCTGTTTTGCCACTCATCTAAAATCACAATGGCATTGGAAAGCGTTCGTCCTCTCGCCTCACCCGGCCAGAGTTTTTCGATATTGTACTTGGTGATCATCTCTTGTACTTTTTTCTCAATCGCCACTTGCGGTTCTTGGGAGTTGTCACGTTTTTTCATCTTCTTTTTAGCAATAAATTCCAATGTGTCATAGAGCGCCATATTGTAAATCCTAAACTTCTCATCATTGCCAGAGAGGTACCCGACATCCGCACCCTTGTCAACACTTTCAATGGAATTGCGCACATAGACGATCTTCTCGTAACTCCCTTTAGTGACCAAGCGCATCGCCGCAACAAAAGCCATCAAGGTTTTACCGCTACCTGCGCGTGCATCGATGACATGAATGTCGTACATATTGGAAAGCAGTGCTTTCATAAAAAATTTTTGTTTGAGGTTGATCGGTTTAATTTCCAAGCCTCTAAAGTCCAACTCTTCATTGAGCATATGAATAATGCCACCTGGAGAGATAATAGCATGTTCTGAATTGCCATCAGAACTGATAAATTCGTAGCAGTAGTTTCCACTTTTATATTCAGGGTCATACTCGCTGATCAGCTTTTTATCGAGTGTGTTGAAAAGGGCTGAATCAACAGGAAGCTGTTTAACAAACTCAAACTCTGGCACATCGCTTCGATCTTCTCTCAAAGACTCTACGGTGACATTGTAAAAAAGTCCAAACATACGCGCATACACATCTAATGAGAGAAAAATAACTTTATAATCAGGATAATACTCTTGAGCACCCGCAGCCACTTCAAGGATACGTTTGTCGTTAGATTCATTAATAAATTGCGAGTCTATATCGGACGTGTAGATCGTCTTGGAAAAAAGATGGATGGAAATATCTTCTTCGTACTGCATCTTGACAACGCGGAAGGGCTCCCCACTGTCCACTTCAATGACTTTACACGAAGCCAGCATCCTAGCAAAGCTTCTGGCTTGGTACCCAAGTTCTGTGAAGTTCTTTTTAAAATCTTCCAGCTCTATAAGCACCGTTTCTGGGATCACAATGATGTTGTTGCCGCCATCACACAACTCTTTGATAAAATTGGTATTGTGCAAGATAATATTGGTATCGAGCACATAAACTTTGTTGACTGACAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP045453|873879:881531|880133_881531_-|WP_096047313.1|DBSCAN-SWA
MSVNKVYVLDTNIILHNTNFIKELCDGGNNIIVIPETVLIELEDFKKNFTELGYQARSFARMLASCKVIEVDSGEPFRVVKMQYEEDISIHLFSKTIYTSDIDSQFINESNDKRILEVAAGAQEYYPDYKVIFLSLDVYARMFGLFYNVTVESLREDRSDVPEFEFVKQLPVDSALFNTLDKKLISEYDPEYKSGNYCYEFISSDGNSEHAIISPGGIIHMLNEELDFRGLEIKPINLKQKFFMKALLSNMYDIHVIDARAGSGKTLMAFVAAMRLVTKGSYEKIVYVRNSIESVDKGADVGYLSGNDEKFRIYNMALYDTLEFIAKKKMKKRDNSQEPQVAIEKKVQEMITKYNIEKLWPGEARGRTLSNAIVILDEWQNSSNNTTQLILSRLDNNCKAIVIGSNRQIDNMYLNRFNNGLTSLLKQTKKEQTHISLFAIELDKSVRGKFSHFADDIFGDGDKHK
>NZ_CP045453|873879:881531|875602_877066_-|WP_167749514.1|DBSCAN-SWA
MAKVVILGGGVAGHTAAQFARKWLNRTHEVVVVTPNSKWNWIPSNIWVGVGQMDQEEVLFDLAPIYAKAGITYIQAKALTIHPEGTVENSKNFVTIEHTGANKEGEKEEITYDYLINATGPRLNFAATEGLGPDNGFTVSVCTASHAKHAADELEKIIEALKKGEEKKILIGTGHGMCTCQGAAFEYTFNVDHRLRAEGVRDKATITYISNEYELGDFGVGGMHLKMGGYITSGKVFAESLYAERDVKWITRAHVNKVEKDKVHYENLAGEMKEETYDFSMLIPPFAGAGMKAYDKNGEDITSSMFNAGGFMFVDGDYSKATAPYETWDASDWPKTCQNPKYKNIFAAGIAFAPPHIISKPMKSPNGTPINPTPPRTGMPSAMMGKAVAASIVDMIGGASAPTHTACMAEMGAACVASAGKGLFSGTAVAMTMYPIIPNYKKYPDYGRDFGGTFGEIGLAAHWVKHLLHHAFIWKAKMKPFWSIIPE
>NZ_CP045453|873879:881531|873879_874560_-|WP_096047310.1|DBSCAN-SWA
MGKIASKALVVFSGGQDSTTCLGWAKNRFDSVESITFDYGQKHRVEIAQAEKIAKALHVKNTLLSLDAFSQLNDSALIDGTQDIGAHHRTHTNLPASFVPNRNAIFFTLAHAFAQKQGIEHIIIGVNQTDYSGYPDCREPFVKALELALNLGSEANITFHYPLMHLTKAETFELSHQEGVLELVIDESHTCYNGVHDKKHAWGYGCGECPACVLRKAGWETYAKGR
>NZ_CP045453|873879:881531|877882_878581_-|WP_087439311.1|DBSCAN-SWA
MTSKDYLTQMFALQQKLNDETNGIGWENGYTKHNRMINWKRCIYMECAELIDSFSWKHWKNINKPTDWDNVTVEIVDIWHFIMSLLLEDYKTNNRGDIEQLVLDVLDVQGFEAFTKEPLSIGMAVPMELVNDIESIIHDTTGFEMDLFDGLLKEYFTLSRKCGINLKVLYKFYVAKNVLNQFRQDHGYKEGHYIKVWNGKEDNEVMLSLLHGESAPTVDALYKKLEKVYPKA
>NZ_CP045453|873879:881531|874559_875138_-|WP_087439308.1|DBSCAN-SWA
MLKVVDIFYSIQGEGAHVGVPSIFIRLYGCNLTCSFCDEFLHKGEYESLSFDEVLTRIKPYPAMNVIITGGEPSIYNLNGFIDYLQAYMYAVSVETNGYNFSNIASANWVTYSPKDWDKIEKYGYDEIKFVVSKESAVEKILEFSSYKPIFIQPQNEMDRPNKENVAFCVEFVKEHPQFILSVQLHKFLGVE
>NZ_CP045453|873879:881531|877241_877781_+|WP_087439310.1|DBSCAN-SWA
MLWQISKEFDFCYGHRVWSQELDAEFSLSGCLACRHLHGHQGKIIVFLQSNELKNGMVTDFHHLNWFKLFLDNTLDHKFIIDIHDPLFATLLPHFADKQNLLSHESGYKTPDLSFIAHEPNYLVEMYEGYIIVDFVPTSENISTWLLQIIAKKMSRLGVEVSHVEFLETPKSRSIVYNH
>NZ_CP045453|873879:881531|879363_880137_-|WP_096047312.1|DBSCAN-SWA
MTKYEFSGDEDPIAFRSIFISDLHLGTRFSQAEELLDFLKFTNSENLYLVGDVIDGWAIKRKIKWAQSHSDVIQKILRKARKGTNVFYITGNHDDFLRSFLPLGLGDRIAVVDEVDYTSLNNERFFITHGDFFDSVTMTKRWLAILGDLGYDLLLNVNQLIGWFRKKMRYHSHWSLSKYVKDNVKSSISFITDFEHILSEHAKRNNYDGVICGHIHKAEIRDIEGIKYLNCGDWVESCTAIVETLEGEFRIIRWLGH
>NZ_CP045453|873879:881531|878596_879379_-|WP_096047311.1|DBSCAN-SWA
MAGTLKISLALSGGAARGAFHLGVIAAMERNNVEIAAVSGCSIGSVIAAGVGSGVSAFDLLRIVKSRAFRKVFHFNYFRKGLLRINEKAAILKEIAPIERLEQMSIPTFMTCVDLPHGEIVRFSHGNTINLAIASSALIPIFRPITYDNYTLIDGGFMDNLPVAPLLELPYPVVSVNLFPLHVKQKSNFFSSFERAIYLSILASSKQQIEQSDLCISDPTLNDFGLFTFRQIDACFELGYRKGSESILTFMAQKSIMKPF
>NZ_CP045453|873879:881531|875280_875430_-|WP_162494884.1|DBSCAN-SWA
MKLTPYSQNAFTPIPSKFTLFRRTCVIWQVIKFIMINIRMTILIIKSHH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096047310.1|873879_874560_-	7-cyano-7-deazaguanine synthase QueC	A0A0A0RPC6	Escherichia_phage	5.2e-67	55.8
WP_087439308.1|874559_875138_-	7-carboxy-7-deazaguanine synthase QueE	A0A2P1CLA1	Pantoea_phage	1.4e-12	30.5
WP_162494884.1|875280_875430_-	hypothetical protein	NA	NA	NA	NA
WP_167749514.1|875602_877066_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_087439310.1|877241_877781_+	6-carboxytetrahydropterin synthase	D5GVR0	Campylobacter_virus	8.9e-38	42.7
WP_087439311.1|877882_878581_-	dUTPase	NA	NA	NA	NA
WP_096047311.1|878596_879379_-	patatin	G8DDB1	Micromonas_pusilla_virus	2.4e-07	26.5
WP_096047312.1|879363_880137_-	UDP-2,3-diacylglucosamine diphosphatase	A0A218MKA7	uncultured_virus	1.2e-62	46.3
WP_096047313.1|880133_881531_-	phosphate starvation-inducible protein PhoH	D5GV52	Campylobacter_virus	7.6e-81	39.9