CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP051487	Pseudomonas umsongensis strain CY-1 chromosome, complete genome	10 crisprs	DEDDh,DinG,csa3,cas3,PD-DExK	2	4	5	0

1. NZ_CP051487

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP051487_1

• CRISPR_ID: NZ_CP051487_1
• CRISPR_location: 2008996-2009106
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_1

Consensus_repeat	Method
TTGGCAAGAGTGAAGCTTATCAGCAGA	CRISPRCasFinder

spacers of NZ_CP051487_1

>1.1|2009023|57|NZ_CP051487|CRISPRCasFinder
CCCTGCGGGATGCCCTCGATATAAAGGACAGGCACATAGAGCAAATAGAGGCGCATC

CRISPR arrays and Neighbor proteins around NZ_CP051487_1

CRISPR arrays

The CRISPR arrays of NZ_CP051487_1

>merge|NZ_CP051487|1|2008996-2009106|CRISPRCasFinder
TTGGCAAGAGTGAAGCTTATCAGCAGACCCTGCGGGATGCCCTCGATATAAAGGACAGGCACATAGAGCAAATAGAGGCGCATCTTGGCAAGAGTGAGGCTTATCAGCAGA

>NZ_CP051487|1|1|2008996-2009106|CRISPRCasFinder
TTGGCAAGAGTGAAGCTTATCAGCAGA	CCCTGCGGGATGCCCTCGATATAAAGGACAGGCACATAGAGCAAATAGAGGCGCATC
TTGGCAAGAGTGAGGCTTATCAGCAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_020800648.1|2019635_2020910_+|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl|CDD|235781
NZ_CP051487.1|WP_168757519.1|2014787_2015822_+|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl|CDD|224014
NZ_CP051487.1|WP_168757510.1|2002219_2003581_+|phosphomannomutase	unknown	unknown	gnl|CDD|185312
NZ_CP051487.1|WP_168757518.1|2013589_2014756_+|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_CP051487.1|WP_168757523.1|2018809_2019604_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223377
NZ_CP051487.1|WP_168757513.1|2005811_2006609_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224596
NZ_CP051487.1|WP_168757512.1|2004353_2005718_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|226906
NZ_CP051487.1|WP_168757520.1|2015872_2017015_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340838
NZ_CP051487.1|WP_168757506.1|1995822_1997565_+|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NZ_CP051487.1|WP_168757521.1|2017014_2018142_+|glycosyltransferase	unknown	unknown	gnl|CDD|340826
NZ_CP051487.1|WP_168757514.1|2006605_2007856_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213187
NZ_CP051487.1|WP_168757507.1|1997578_1998907_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NZ_CP051487.1|WP_168757508.1|1998903_2000301_+|TolC-family-outer-membrane-protein	unknown	unknown	gnl|CDD|273829
NZ_CP051487.1|WP_168757516.1|2009683_2012680_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340838
NZ_CP051487.1|WP_168757517.1|2012682_2013579_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|187570
NZ_CP051487.1|WP_168757522.1|2018263_2018599_+|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378965
NZ_CP051487.1|WP_033045097.1|2020906_2021464_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_CP051487.1|WP_168757511.1|2003763_2004357_+|adenylyl-sulfate-kinase	unknown	unknown	gnl|CDD|179661
NZ_CP051487.1|WP_168757509.1|2000651_2002094_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|273648
NZ_CP051487.1|WP_168759147.1|1994112_1994934_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_020800648.1|2019635_2020910_+|beta-ketoacyl-ACP-synthase-II	gnl|CDD|235781	PRK06333, PRK06333, beta-ketoacyl-ACP synthase.	0
NZ_CP051487.1|WP_168757519.1|2014787_2015822_+|GDP-mannose-4,6-dehydratase	gnl|CDD|224014	COG1089, Gmd, GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_CP051487.1|WP_168757510.1|2002219_2003581_+|phosphomannomutase	gnl|CDD|185312	PRK15414, PRK15414, phosphomannomutase.	0
NZ_CP051487.1|WP_168757518.1|2013589_2014756_+|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.29309e-22
NZ_CP051487.1|WP_168757523.1|2018809_2019604_+|SDR-family-oxidoreductase	gnl|CDD|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	3.30705e-89
NZ_CP051487.1|WP_168757513.1|2005811_2006609_+|ABC-transporter-permease	gnl|CDD|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	9.51155e-47
NZ_CP051487.1|WP_168757512.1|2004353_2005718_+|FAD-dependent-oxidoreductase	gnl|CDD|226906	COG4529, COG4529, Uncharacterized protein conserved in bacteria [Function unknown].	5.31559e-79
NZ_CP051487.1|WP_168757520.1|2015872_2017015_+|glycosyltransferase-family-4-protein	gnl|CDD|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	4.07856e-114
NZ_CP051487.1|WP_168757506.1|1995822_1997565_+|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP051487.1|WP_168757521.1|2017014_2018142_+|glycosyltransferase	gnl|CDD|340826	cd03795, GT4_WfcD-like, Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.	1.16419e-173
NZ_CP051487.1|WP_168757514.1|2006605_2007856_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213187	cd03220, ABC_KpsT_Wzt, ATP-binding cassette component of polysaccharide transport system. The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.	8.91778e-96
NZ_CP051487.1|WP_168757507.1|1997578_1998907_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	2.96235e-110
NZ_CP051487.1|WP_168757508.1|1998903_2000301_+|TolC-family-outer-membrane-protein	gnl|CDD|273829	TIGR01844, Proteases_secretion_protein_PrtF, type I secretion outer membrane protein, TolC family. Members of this model are outer membrane proteins from the TolC subfamily within the RND (Resistance-Nodulation-cell Division) efflux systems. These proteins, unlike the NodT subfamily, appear not to be lipoproteins. All are believed to participate in type I protein secretion, an ABC transporter system for protein secretion without cleavage of a signal sequence, although they may, like TolC, participate also in the efflux of smaller molecules as well. This family includes the well-documented examples TolC (E. coli), PrtF (Erwinia), and AprF (Pseudomonas aeruginosa). [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Porins].	2.04253e-61
NZ_CP051487.1|WP_168757516.1|2009683_2012680_+|glycosyltransferase-family-4-protein	gnl|CDD|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	4.71639e-38
NZ_CP051487.1|WP_168757522.1|2018263_2018599_+|helix-hairpin-helix-domain-containing-protein	gnl|CDD|378965	pfam12836, HHH_3, Helix-hairpin-helix motif. The HhH domain is a short DNA-binding domain.	4.18796e-23
NZ_CP051487.1|WP_033045097.1|2020906_2021464_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.67732e-10
NZ_CP051487.1|WP_168757511.1|2003763_2004357_+|adenylyl-sulfate-kinase	gnl|CDD|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	5.54949e-105
NZ_CP051487.1|WP_168757509.1|2000651_2002094_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase	gnl|CDD|273648	TIGR01479, Mannose-1-phosphate_guanylyltransferase, mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. This enzyme is known to be bifunctional, as both mannose-6-phosphate isomerase (EC 5.3.1.8) (PMI) and mannose-1-phosphate guanylyltransferase (EC 2.7.7.22) in Pseudomonas aeruginosa, Xanthomonas campestris, and Gluconacetobacter xylinus. The literature on the enzyme from E. coli attributes mannose-6-phosphate isomerase activity to an adjacent gene, but the present sequence has not been shown to lack the activity. The PMI domain is C-terminal. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	0
NZ_CP051487.1|WP_168757517.1|2012682_2013579_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|187570	cd05260, GDP_MD_SDR_e, GDP-mannose 4,6 dehydratase, extended (e) SDRs. GDP-mannose 4,6 dehydratase, a homodimeric SDR, catalyzes the NADP(H)-dependent conversion of GDP-(D)-mannose to GDP-4-keto, 6-deoxy-(D)-mannose in the fucose biosynthesis pathway. These proteins have the canonical active site triad and NAD-binding pattern, however the active site Asn is often missing and may be substituted with Asp. A Glu residue has been identified as an important active site base. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.80209e-49

Protein sequences

>NZ_CP051487.1|WP_168757514.1|2006605_2007856_+|ABC-transporter-ATP-binding-protein
MSLLLVENLGKSYRTYRSEWQRFARWFGVSVKPHTEHWVLRNISFSIDPGQSIGVLGKNGAGKSTLLKMITGTLQPSEGRVALNGRISAILELGMGFNPELTGRQNVMHSAGLMGFSRDQIDQALPDIEAFSDIGEYFDQAVRTYSSGMQSRVSFAVATAFHADILIVDESLAVGDAAFQRKCFRRLEDMIELGTTLLFVSHDIESVKKICSKALHINNGGLVEFGDAKSVCDNYERTLFSKPVVDGGDEVEHVAIDLALQTDCEVTYGDGRAFIQAITLKDQDGNPANVLKNNEIMKIHYSVKFFQAVNNPVFTCLVKTREGIAVSGTDSMFLKERVGKVEPGQTVDVEFSFNAALVPGIYYVNCGIRDAEGEGVDFIHRRVDAAIFRVTSNHKTTALVGFVDLHTTLSIGVGHE
>NZ_CP051487.1|WP_168757513.1|2005811_2006609_+|ABC-transporter-permease
MFGMFKNLWRYRGFVASSIANEFSVRFARSKLGGLWMVIHPLTQVAIYALILSNVLSAKLPGIDNKYAYAIYLVAGMLGWSLFTEIVSKCLTLFTDQGNLMKKMIFPRITLPAIAVGSSLVNNLFLFAAVMLVLAFLGNFPGDTILWLVPLYALLVSLAVGVGLIFGVLNVFVRDVGQVVPIFLQLLFWFTPIVYPIKVIPEELQQVVMMNPLYPIITSFHNVLVYHRAPDFDCSMLTLFACSLGLLILGLFIFRRAAPEMVDSL
>NZ_CP051487.1|WP_168757512.1|2004353_2005718_+|FAD-dependent-oxidoreductase
MKKVVAIVGAGFSGSAVAIQLLGQLHSAASVILIDSAATSGGVAYRTSHQTHLLNVPAGNMSALPQDPDSFVEYCRRSLQDVEGGTFVPRALYARYLTYLLGDASERNTCGGTLTRLTARVVGMDLSGATGVLTLANGERIQVDHVVLATGHLVPNTPSQALQVLSHVHYVSDPWTGNLDKLAQRSRDVLLVGSGLTSLDVVRQLRACGHRGTIFMVSRRGLMPNAHRDALPLRQHHEEFLGSLLVSTPSVSEYLRLVRRYIGKGRVEGWDWRDVIAALRPITPQLWQRLNREEKLRFRRHLQVFWDVHRHRIAPCVSDELQHLRGLGIIKPVAGAIVKVLRDGDGVRVFIRLRGDRGEFQCHVARVINCTGPGTDVARAGDVLVEQLVSEGVLQDVLNGMGIRVDGMYRVASGLDQVSYIGPLLRAEYWEATAVPELRQHAFNVANIIFDRIG
>NZ_CP051487.1|WP_168757511.1|2003763_2004357_+|adenylyl-sulfate-kinase
MKNNLTLHPESVSAQQRCDLKDQKPIVLWLTGLSGAGKSTIANALEVELHARQRHTYLLDGDNVRTRLCGDLGFSEEDRQENIRRISEVSRLFVESGLIVITAFISPSLRDRAMAREIIGESAFVEVYIATPLSECERRDPKGLYRKAREGLIKNFTGIDAIYEAPVNPDITINTVDESLHESIGRIIHYLDEKFSR
>NZ_CP051487.1|WP_168757510.1|2002219_2003581_+|phosphomannomutase
MYLPIQTHCFKAYDIRGQVPAQLNDDIAYRIGRALVAELNGKSFVVGRDMRLESPLLANALIRGITEAGADVIDIGLCGTEEVYFATSHYKVDGGVMITASHNPKGYNGMKLVRAESRPISGDTGLDAIRDRVDRGDLGELAMSAGQVREAFDKAAYLEHLLGYVDVKSLKPLKFLADPGNGAAGPVIEALQSRLPLQWVLINAEPDGIFPNGVPNPLLPENRELTRKALLDNGCDLGLAWDGDFDRCFFFDADGRFIEGYYLVGLLAEMLLKLHPGSKIIHDPRLTWNTIEQVEQAGGIAIQSKTGHAFIKERMRAEDAVYGGEMSAHHYFRDFAYCDSGMIPWLLVAALMSETGKTLAQLVDERIEAFPCSGEINYKVDDVKATLSRILAHFQPLNPVLDETDGISLAFQDWRFNLRGSNTEPLLRLNVESRGSRDLVSRYVEEIETLIRR
>NZ_CP051487.1|WP_168757509.1|2000651_2002094_+|mannose-1-phosphate-guanylyltransferase/mannose-6-phosphate-isomerase
MELIPVILSGGVGSRLWPVSREAHPKPFMTLPDGQNLIQKTFLRASKLESVVEVLTVTNRELLFKTEDEYQAINSAGLAQGYILEPFGRNTAAAVTAAALQLKEVHGADAQMLVLAADHLIQDEGAFAAAVAKAVKLASQGWLVTFGIQPQYPETGFGYIETAKGASLDGGLKVERFVEKPDLNTAESYIAAGNYYWNSGMFCFRVGTVIEELEKHAPDVVTAVTKTLEQSRRTTATGYSCLALHAETFANVPDISIDYALMERSSKVATIPCDIGWSDIGSWNAVSDLTGPDSDGNRFEGEVISHGSRNNYVNSEDRLTALVGVEDLLVVDTPDAVLIAHKDHAQDVKHIVGQLKSKGHHLHLLHRTVHRPWGTYTTLENGERFKIKRIVVKPGASLSLQMHHHRSEHWIVVSGMAVVFNDDKELMLDTNESTFIRAGHKHRLKNPGVIDLVLIEVQSGDYLGEDDIVRFEDNYGRVDK
>NZ_CP051487.1|WP_168757508.1|1998903_2000301_+|TolC-family-outer-membrane-protein
MIVRLLPVVLLGLSVFQVQAAPMQEKTGVSANDYSVDLLALYHESRLEDPRIISAYAKARSASEQQRAALGGLLPQVSANGGYNRILRKDDASREIYDNSNYGLSLTQYIYNKQAWESWQKSKSVSRQKVSEADEAQAEATVDLAKRYFVALAADDDLELVMAERRATQKNLDQVNALYARHMAKITDQLDLQARVDSLAAQEVESRNQVRLSRAALAELVGRPINERLSRVRSDVEFQAPMESLDNWLQLAESGNPALKASQSGVEAAEAAVREGKGGHYPSLTFSLSGQQSDVGYDNTQTPRSDSYVATLGVKVPLYSGGSTSARVRGLYDDQQVAEEQMEGVRRQVVKETTNAYLTAQSSVEKIRASRNALSSASQSSIAAQKAFTYGVVNAVDVLASVQNEFKARRDLLKAQYDFVISLFALNRWAGKLSEGSVASVNAWLSAGDINVIRPDAPNPKQVSR
>NZ_CP051487.1|WP_168757507.1|1997578_1998907_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MTRTTLITLNDDDLDEVPTSDRNIRRLGLGIVLLTFGLFGGWAAFAPLDNAVFGSGQVTVQSYRKTVQHLEGGIVKELLVHDGDLVRQGDPLIVLDESQISAEYESTRSQLIAAKTREARLRAERDDLPALPRVSIDGPDSQRAQEALEGETHVFNARRGSRLGEVAVKKERIAQLSQQITGLEAMVRTKVGLEQSYSGEITELQELLAQGFVDKQRLLEQERKLDMLRSEVADHKSNILTTRLQINETQLEIVQLTKNFNSDVVKDLADVQSQVFDLQEKVSALKDRLSRIVIRAPEGGMVLDMKVHTVGGVISPATPLMDIVPEASQLVVEARVGTNDIDRISLGKTADIRFTAFNYATTPVIQGEVSRISADRLTDERSGDSYYLVRVTLTDEGAKKLGERKLLPGMPAEVLINAGDRTMLQYLLKPARNMFAKSMIEE
>NZ_CP051487.1|WP_168757506.1|1995822_1997565_+|type-I-secretion-system-permease/ATPase
MSRLPENNLQAALRVCKSSFISVGFFSLFVNALMLVPTFFMIQVSGRVVPSSSVSTLVMLTLILTVLMLTLGSLEWVRSRIMVRISNRLDALLSHDVYRASFRRALNSGGMDASAQSLNDLTSLRQFLSGNGLFAFFDAPWLPIYVAVMFMFHPVYGWVTVGCAIVLICLAVLNQRFTGKALVEANKENVAASLHTTKTLRNAEVIESMGMLRTLMSRWAQRQRKVLRLQSYASDKSGIITSVSKTFRQWTQSMMLALGAYLVITHEITPGLLMAGSLLLGRALSPIDQMIGSWKGFVGARVQYNRLNETLEKLSAEPERMKLPAPQGHIQVENLIVTPPGAKTPVIRNISFVAPAGTVVGIVGPSAAGKSTLVRTLMGVWAPQHGVVRLDGADISAWDKHELGPHVGYLPQDIELFEGSISENIARFEAIDAEKTVHAAKVAGVHEMILMLPDGYDTVIGSDGVNLSGGQRQRIGLARALYGSPRLIVLDEPNSNLDDVGERALGVALQKIKETGATVFIVSHRPNILARLDRVMVLSAGTISLYGAREQVIAELAAQQAKTQQRVAQAAASDAASAGA
>NZ_CP051487.1|WP_168759147.1|1994112_1994934_-|hypothetical-protein
MYIFRYASQTSTDKTVCIALQQAPLGKGLIDFFPAEGVSKNMLTKLGDCIIGRVKNGVTTVLITEYHLANVQVDPVDLRIDRIDTSAAIMRNFAPPAPAKETSSALHPAVAPGTLKLIGHIQSRGDVTATQEWLGERQGTTGIEGFLVDWADRPDGVDLVYTSTVAGSGPSPKILSGHYCGTRGKATPLIAVGFSLTGPNSSHYRLAGEVAFAGAEPQPIVVDQMFFGPSGQEPLVGIKLSIFAHPEINAPRYKSPWENLATTQPYSHEGQLA
>NZ_CP051487.1|WP_168757516.1|2009683_2012680_+|glycosyltransferase-family-4-protein
MYGFERTEEVNNRTIWIDITTSQQWTGGVVGIVRAELEIAASLNKHYPDIRFSKFDNGHFVEVDKGSLPWLRGEVSVAEAYLAGRSAATSAPQVSEGNRSKVDVYLDKLASEIPSRSRRLQHGMLLAVSSLPARHQKLGMYLTWLPRKLLGAAVRLRSLFPAQTIPRAASYSPQAVSPVLSYPYQKGDMVVAMGWLDSGKEAFYTRLKARDPSIQLVYMVYDTILVGESTHHLYRPQEEDSFRSYFHWISETCDYILYAGNNPQEDGIAYQEKMGWRTPPSLSVPFGGTDLSKEESTADDARILKGLGITGPFILTVGTIEVRKNHDTLYKAYVSLIEGKSENIPQLVFAGKPGWRTADLIDTIRRDPRVAGKLLLLTPTDGELTALYRNCRFTLLPSFYEGWSLPMPEGLSYGKLCLASDVAPLREIGQEFPEYIHPLDVMGWANKIEYYCNNDEALEAKENNIKNNWRGTTWDKCGQDVLDSIRDFAGRELPATDGLSLWVDLTLSYAVWRGGVTGIIRSELILAHYLEKLVPGVRFFGFHEGKFFEVPRDRLEWLFASTDVNKQYAEFQRFWADAEMRGLGHRVPTHVFSQPSSPAAPAQIPLLASVAPNTLSKKEKIRNSAGYVLSALPTQLQKMLISLAVRSGVVGRLSSAGVVSSGDFVPHLNEDNVPAIFEEPLKGIAQDLPFGMNDMVFSAGINWDQQPLLELIKAKRNSSFHVAQIIYDMTPLITPHLHAKEAYNWYQRFFYLAGLASDKIIYGGETAMRDGQKWQREHHWPATPGLPIKFGSDIAPQTDHSMDEQMLLEMGVTGPFMLSVGTLEVRKNHETLYKAYLKLLEEGCPDLPQMVFVGGAGWKAQDLFDIITRDKRVVGKILILRTTDPQLDVLYRHCQFTLLSSLYEGWSLTLPESLGYGKFCLTSDVDPLRETGRDLVDYIHPWDVSGWADKIKFYSSHPEALALREAKIRDEWATITWQKCAEGLVESLSAIVKESKGH
>NZ_CP051487.1|WP_168757517.1|2012682_2013579_+|NAD-dependent-epimerase/dehydratase-family-protein
MNGTRVLVTGGSGFIGRYLIEELKARGATVLGTCIGQATEGLVAVSLTDKAKLTSIIEEFAPDWIVHLAAIALVTHGDVQQIYGVNVLGTENLFNAVIDAQIPRPTMLLASTAGVYGNQQSEFLHEGLEYKPANHYSYSKMVMEMLARQYQDDIKVHVVRPFNIIGSGQSESFLIPKIVRHFYDRAPVLKLGNISSVRDYVEVHRCAWMVAELMSKQHDSPFTVNLCAGRGWTGYDVLDCLTDISGYRPDIEVADQFVRKNEVWRLVGSPERLHQLLGTDPQLPDLSKILESMYKSMK
>NZ_CP051487.1|WP_168757518.1|2013589_2014756_+|acyltransferase
MAAELFYYVLLGALFPLGCCYLLLISRKVGIEQTHLVGFSGSLEALRGVAAFLVFGAHSSMYFGFAPKQVAAASMGEIGVLLFFMLTGHLFWGQIKAGKFDGNTFFIKRIRRLFPIMLVVIATFTLLDWIKAGFVVPSASQVLAGFRNFGFAFGKVVNSVGDVNDVFTKDMYLRINNIWTLRWEWLFYLCMPLLAALGSFPKVTAFAIAIILLFMDPFQILQGSTDAVFVLAFWLGGMSRSLEDFRATKLAILFSRKVSSCLLLLGILATGAYLFGGELSQKNVRVPVLIFLVFPIFFYFVASKHFPDRLGSKGMQLMGKISYSFYLWHLGVNYYVVRWVAKFFEDSQSLTCFVVSCMVMMIVGLTLASFTYRYVEEPFLKKSTHNTI
>NZ_CP051487.1|WP_168757519.1|2014787_2015822_+|GDP-mannose-4,6-dehydratase
MKTAIITGITGQDGAYLAELLLEKGYTVYGTFRRTSSVNFWRIEELGINNHPNLHLIEYDLTDLSASIRMLQTTKPVEVYNLAAQSFVGVSFDQPITTAEITGVGVVNLLEAIRIVNPSIRFYQASTSEMFGKVQSIPQKEDTPFYPRSPYGVAKLYAHWITINYRESYGIFASSGILFNHESPLRGREFVTRKITDSVAKIKLGKLDVLELGNLDAKRDWGFAKEYVEGMWRMLQADEPDTFVLATNRTETVRDFVSMAFKAAGITVRFEGQGENEFGLDADSGKVIVRINPKFYRPTEVDLLIGDPAYAKKVLGWEPTTQLEELCRMMVEADLRRNEIGFSF
>NZ_CP051487.1|WP_168757520.1|2015872_2017015_+|glycosyltransferase-family-4-protein
MKIILSVEPVRFPLTGIGRYTYELAKELRLSDQVDDLKFFSGSRFLPALPSAVGESNKIHGIKRAMQKSALVLEGYRLVMPYLRQRSLRDSKEYLYHSPNYYLPPFTGRSVATFHDLSPFTMAHCHAPKLVRYLQKELKATLVRADALITDSEYTRKELADYFAWPIERIYTVPLASSGEFHPRIPEVLRDTLVRHGLKVGGYSLFVGTIEPRKNIETLLDAYSRLPEAVRSRWPLILTGYHGWQNDAINARLETARREGWAHYLGFVPSEDLPLLFAGARLFTFPSLYEGFGLPVLEAMSSGVPVVCSNSSSLPEVAGDAALMCEPMDVDALTAHLLQGLEDESWRNQAIERGLLHAAKFTWERCAHETIQVYRKVLQG
>NZ_CP051487.1|WP_168757521.1|2017014_2018142_+|glycosyltransferase
MSKVLHFFKTYYPETMGGIEQVIFQIAEGCAIHGFDAEVLYLSDRGAARNERVGHHVTHRAKLDLHVASTGFSLSAFKDFAELAEQADIIHYHFPWPYMDLVHFATRLNKPTVASYHSDVVKQKYLLKLYQPLMNRFLSSVDCIVASSPKYAQSSPVLRRFEEKVRIIPYGLDRGTYPIPSTAMRKHWHSLLGERFFLFVGALRYYKGLDYLLEAAKHTQLPVVIVGGGHLEDELKAQAIHMGLTNVRFLGVLPNEDKVTLLQLCYAFVFPSHLRSESFGISLLESAMYGKPMISCEMGSGTTFINIADETGLVVPPRDATALARAMEALWQNPRRAAEMGLRAKERYEEVFSANVMAESYANLYQELLSGSPRQ
>NZ_CP051487.1|WP_168757522.1|2018263_2018599_+|helix-hairpin-helix-domain-containing-protein
MRIGYFYSLVFALLTSASITANAAPAGKPEASKAPVAMEASAGVQSGKVNLNKADAPTLQRELSGVGEAKAKAIVAYREANGPFASPEELLEVKGFGKALLDKNREKLQVN
>NZ_CP051487.1|WP_168757523.1|2018809_2019604_+|SDR-family-oxidoreductase
MTSIQSQGTALVTGASSGIGAVYAQRLAARGFDLLLVARDQERLEAAASALRDAHGVQVEVLKADLTQKDDVLKLEQRLRSDSSISLLLNNAGIAADGLLANADLDQLERMIQLNITAVTRLASAAAASFAKAGRGTIINIASVVALFPERFNATYSASKAYVLSLTQSLNAELDGTGVKVQAVLPGVTRTEIWERSGIDASQIPEDMVMEAGEMVDAALAGLDQGELVTIPSLPDAGDWDAFVAARLVMAPNLSKSKAAARYK
>NZ_CP051487.1|WP_020800648.1|2019635_2020910_+|beta-ketoacyl-ACP-synthase-II
MSDRRVVVTGMGLVSPLGSGVEAVWARLLAGRSGLRNLPDEVVADLPAKVGGAVQTVAQDPEAGFDPDRATAPKEQKKMDRFILFAMEAARQAIEQAGWQAQTAQAQERTATIIGSGVGGFGAIADAVRTTDSRGPRRLSPFTIPSFLVNLAAGHVSIEHGFKGPLGAPVTACAAGVQAIGDAVRLIRCGEADVAVCGGAEAAIDRVSLAGFAAARALSSAFNDTPERASRPFDRDRDGFVMGEGAGLLVVESLEHALARGAQPLAEVVGYGTSADAYHLTAGPEDGSGARRAMSLALAQAGILPEQVQHLNAHATSTPVGDLGELAAIKALFGSQNGIAVTSTKSATGHLLGAAGGIEAIFTLLAIRDQIVPATLNLDNPDPASEGVDIVRGQARPMAIEYALSNGFGFGGVNASVLFKRWVG
>NZ_CP051487.1|WP_033045097.1|2020906_2021464_-|TetR/AcrR-family-transcriptional-regulator
MRYSQDHKAQTHQRIIKEASVRFRRDGIGATGLQPLMKALGLTHGGFYSHFKSKDELVEKALQAAGDQVDVTCAELFSQDRPLEAFINAYLSEWHQTSPHEGCPLPTMSSELGMRGQPSPTSDAVLHARLRQIQGTLEGENIERRSIVIMSTLIGALLLSRSVENPELAAEILEVTRTHLNQPDN

Crispr_ID: NZ_CP051487_2

• CRISPR_ID: NZ_CP051487_2
• CRISPR_location: 2266869-2266999
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP051487_2

Consensus_repeat	Method
GGCAACGACATCCTCAACGGCGG	CRISPRCasFinder

spacers of NZ_CP051487_2

>2.1|2266892|31|NZ_CP051487|CRISPRCasFinder
CGCCGGTATCGACCAGTTGTTGGGCGGCACT
>2.2|2266946|31|NZ_CP051487|CRISPRCasFinder
CGACGACAATGACGTCCTCAATGGCGAGGAC

CRISPR arrays and Neighbor proteins around NZ_CP051487_2

CRISPR arrays

The CRISPR arrays of NZ_CP051487_2

>merge|NZ_CP051487|2|2266869-2266999|CRISPRCasFinder
GGGAACGATACGCTCAATGGCCTCGCCGGTATCGACCAGTTGTTGGGCGGCACTGGCAACGACATCCTCAACGGCGGCGACGACAATGACGTCCTCAATGGCGAGGACGGCAACGACACCCTCAACGGCGG

>NZ_CP051487|2|2|2266869-2266999|CRISPRCasFinder
GGGAACGATACGCTCAATGGCCT	CGCCGGTATCGACCAGTTGTTGGGCGGCACT
GGCAACGACATCCTCAACGGCGG	CGACGACAATGACGTCCTCAATGGCGAGGAC
GGCAACGACACCCTCAACGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_033044693.1|2246540_2247836_+|MFS-transporter	unknown	unknown	gnl|CDD|340870
NZ_CP051487.1|WP_020800152.1|2247890_2248763_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|132382
NZ_CP051487.1|WP_168757615.1|2280018_2281374_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|379355
NZ_CP051487.1|WP_168757603.1|2249748_2250693_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_CP051487.1|WP_168757604.1|2253280_2254621_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|130902
NZ_CP051487.1|WP_151141366.1|2254627_2256364_-|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl|CDD|226969
NZ_CP051487.1|WP_168757600.1|2244542_2244965_-|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl|CDD|378915
NZ_CP051487.1|WP_168757606.1|2268689_2271497_+|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259934
NZ_CP051487.1|WP_168757614.1|2279500_2280004_+|N-acetyltransferase	unknown	unknown	gnl|CDD|224168
NZ_CP051487.1|WP_168757602.1|2248849_2249677_+|phosphonoacetaldehyde-hydrolase	unknown	unknown	gnl|CDD|184075
NZ_CP051487.1|WP_168757611.1|2276474_2277545_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
NZ_CP051487.1|WP_168757609.1|2275304_2275853_+|cytochrome-b	unknown	unknown	gnl|CDD|225580
NZ_CP051487.1|WP_168757607.1|2271732_2272941_+|MFS-transporter	unknown	unknown	gnl|CDD|340928
NZ_CP051487.1|WP_168757610.1|2276085_2276436_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|223713
NZ_CP051487.1|WP_168757613.1|2278938_2279436_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_CP051487.1|WP_168757612.1|2277597_2278815_-|MFS-transporter	unknown	unknown	gnl|CDD|340913
NZ_CP051487.1|WP_033042802.1|2251950_2253279_-|TolC-family-outer-membrane-protein	unknown	unknown	gnl|CDD|273829
NZ_CP051487.1|WP_168757608.1|2273275_2274772_+|DUF1254-domain-containing-protein	unknown	unknown	gnl|CDD|227659
NZ_CP051487.1|WP_168759151.1|2250818_2251718_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|182990
NZ_CP051487.1|WP_168757601.1|2245264_2246356_+|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|274566

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP051487.1|WP_168757610.1|2276085_2276436_+|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	1.2e-12	43.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_033044693.1|2246540_2247836_+|MFS-transporter	gnl|CDD|340870	cd17312, MFS_OPA_SLC37, Organophosphate:Pi antiporter/Solute Carrier family 37 of the Major Facilitator Superfamily of transporters. Organophosphate:Pi antiporters (OPA) are integral membrane proteins responsible for the transport of specific organophosphates or sugar phosphates across biological membranes with the simultaneous translocation of inorganic phosphate into the opposite direction. The OPA family is also called solute carrier family 37 (SLC37) in vertebrates. Members include glucose-6-phosphate (Glc6P) transporter (also called translocase or exchanger), glycerol-3-phosphate permease, 2-phosphonopropionate transporter, phosphoglycerate transporter, as well as membrane sensor protein UhpC from Escherichia coli. UhpC is both a sensor and a transport protein; it recognizes external Glc6P and induces transport by UhpT, and it can also transport Glc6P. Vertebrates contain four SLC37 or sugar-phosphate exchange (SPX) proteins: SLC37A1 (SPX1), SLC37A2 (SPX2), SLC37A3 (SPX3), and SLC37AA4 (SPX4). The OPA/SLC37 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.24535e-86
NZ_CP051487.1|WP_020800152.1|2247890_2248763_+|LysR-family-transcriptional-regulator	gnl|CDD|132382	TIGR03339, phn_lysR, aminoethylphosphonate catabolism associated LysR family transcriptional regulator. This group of sequences represents a number of related clades with numerous examples of members adjacent to operons for the degradation of 2-aminoethylphosphonate (AEP) in Pseudomonas, Ralstonia, Bordetella and Burkholderia species. These are transcriptional regulators of the LysR family which contain a helix-turn-helix (HTH) domain (pfam00126) and a periplasmic substrate-binding protein-like domain (pfam03466). [Regulatory functions, DNA interactions].	2.21855e-73
NZ_CP051487.1|WP_168757615.1|2280018_2281374_+|FAD-dependent-oxidoreductase	gnl|CDD|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	5.60682e-24
NZ_CP051487.1|WP_168757603.1|2249748_2250693_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	7.41312e-07
NZ_CP051487.1|WP_168757604.1|2253280_2254621_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	8.61923e-112
NZ_CP051487.1|WP_151141366.1|2254627_2256364_-|type-I-secretion-system-permease/ATPase	gnl|CDD|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NZ_CP051487.1|WP_168757600.1|2244542_2244965_-|nuclear-transport-factor-2-family-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.92584e-09
NZ_CP051487.1|WP_168757606.1|2268689_2271497_+|multicopper-oxidase-domain-containing-protein	gnl|CDD|259934	cd13866, CuRO_2_BOD, The second cupredoxin domain of Bilirubin oxidase (BOD). Bilirubin oxidase (BOD) catalyzes the oxidation of bilirubin to biliverdin and the four-electron reduction of molecular oxygen to water. It is used in diagnosing jaundice through the determination of bilirubin in serum. BOD is a member of the multicopper oxidase (MCO) family that also includes laccase, ascorbate oxidase and ceruloplasmin. MCOs are capable of oxidizing a vast range of substrates, varying from aromatic compounds to inorganic compounds such as metals. Although the members of this family have diverse functions, majority of them have three cupredoxin domain repeats. The copper ions are bound in several sites: Type 1, Type 2, and/or Type 3. The ensemble of types 2 and 3 copper is called a trinuclear cluster. MCOs oxidize their substrate by accepting electrons at a mononuclear copper center and transferring them to the active site trinuclear copper center. The cupredoxin domain 2 of 3-domain MCOs has lost the ability to bind copper.	7.88868e-57
NZ_CP051487.1|WP_168757614.1|2279500_2280004_+|N-acetyltransferase	gnl|CDD|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	5.58304e-47
NZ_CP051487.1|WP_168757602.1|2248849_2249677_+|phosphonoacetaldehyde-hydrolase	gnl|CDD|184075	PRK13478, PRK13478, phosphonoacetaldehyde hydrolase; Provisional.	3.62087e-167
NZ_CP051487.1|WP_168757611.1|2276474_2277545_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.37466e-57
NZ_CP051487.1|WP_168757609.1|2275304_2275853_+|cytochrome-b	gnl|CDD|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	8.65287e-38
NZ_CP051487.1|WP_168757607.1|2271732_2272941_+|MFS-transporter	gnl|CDD|340928	cd17370, MFS_MJ1317_like, MJ1317 and similar transporters of the Major Facilitator Superfamily. This family is composed of Methanocaldococcus jannaschii MFS-type transporter MJ1317, Mycobacterium bovis protein Mb2288, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.42529e-122
NZ_CP051487.1|WP_168757610.1|2276085_2276436_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	3.56752e-11
NZ_CP051487.1|WP_168757613.1|2278938_2279436_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	5.29016e-19
NZ_CP051487.1|WP_168757612.1|2277597_2278815_-|MFS-transporter	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.88498e-41
NZ_CP051487.1|WP_033042802.1|2251950_2253279_-|TolC-family-outer-membrane-protein	gnl|CDD|273829	TIGR01844, Proteases_secretion_protein_PrtF, type I secretion outer membrane protein, TolC family. Members of this model are outer membrane proteins from the TolC subfamily within the RND (Resistance-Nodulation-cell Division) efflux systems. These proteins, unlike the NodT subfamily, appear not to be lipoproteins. All are believed to participate in type I protein secretion, an ABC transporter system for protein secretion without cleavage of a signal sequence, although they may, like TolC, participate also in the efflux of smaller molecules as well. This family includes the well-documented examples TolC (E. coli), PrtF (Erwinia), and AprF (Pseudomonas aeruginosa). [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Porins].	2.72747e-84
NZ_CP051487.1|WP_168757608.1|2273275_2274772_+|DUF1254-domain-containing-protein	gnl|CDD|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	1.05189e-84
NZ_CP051487.1|WP_168759151.1|2250818_2251718_+|LysR-family-transcriptional-regulator	gnl|CDD|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.28174e-60
NZ_CP051487.1|WP_168757601.1|2245264_2246356_+|iron-containing-alcohol-dehydrogenase	gnl|CDD|274566	TIGR03405, iron-containing_alcohol_dehydrogenase, phosphonate metabolism-associated iron-containing alcohol dehydrogenase. This small clade of iron-containing alcohol dehydrogenases of the pfam00465 family is found in genomic contexts indicating a role in the metabolism of phosphonates. In Delftia acidovorans SPH-1, the gene ZP_01580650.1 is adjacent to and running in the same direction as ZP_01580649.1 encoding the enzyme phosphonatase (PhnX, TIGR01422). Upstream are also found genes encoding components of a phosphonate ABC transport complex. In Ralstonia eutropha H16 and Verminephrobacter eiseniae EF01-2 the dehydrogenase is followed by a homolog of the PhnB gene, a putative phosphonate-specific MFS-type transporter. In Azoarcus BH72 the gene is preceded by Phosphoenolpyruvate phosphomutase (aepX) and a putative phosphonopyruvate decarboxylase (aepY), two genes involved in the biosynthesis of phosphonoacetaldehyde (Pald). Ususally these two are accompanied by a specific transaminase, AepZ, which converts Pald to 2-aminoethylphosphonate (2-AEP). 2-hydroxyethylphosphonate (2-HEP), the presumed product of the reaction of Pald with an alcohol dehydrogenase, is a biologically novel but reasonable analog of 2-AEP and may be a constituent of as-yet undescribed natural products. In the case of Azoarcus, downstream of the dehydrogenase is a CDP-glycerol:glycerophosphate transferase homolog that may indicate the existence of a pathway for 2-HEP-derived phosphonolipid biosynthesis.	0

Protein sequences

>NZ_CP051487.1|WP_151141366.1|2254627_2256364_-|type-I-secretion-system-permease/ATPase
MHKQSSARSELSDAIFRLRRSFYSLAAFSGVINVMMLTPAVYMLQVYDRALVSRNVTTLTMLTLLVIGLFLLMSTLEMVRTRVLIRVGNCLDMDLNRRIFTAAFERNLSRAGGNPAQALQDLSQVRQFLTGNGLFAFFDAPWTPIYLLVAYLIHPLLGLITLIGSLILVGLAYLTEKATQKPLAEANQAALSSATYANNNLRNAEVIEAMGMLPSISKRWYQSHLRILEMQTLASDRAALISSTGRFVRITLQSLILGAGALLAIEGKITPGMMIACSILTGRALGPVEQVIGSWKQLLGCRSAWGRLNEMLHDYPRRPPSMPLQRPLGMLAVENVYAGAPATNNTILRGVSFSLAHGESLGVIGPSASGKSTLARLLVGVWPAQAGKVRLDGADIFSWNKGELGPWLGYLPQDVELFEGTIADNIARFGEVDSDAVIRAARSTGVHEMILRFAQGYDTRLGTDGSPLSGGQKQRIALARALYGEPNLIVLDEPNANLDDVGEKALVDALAELKARGATVILISHRPNVLCAVDKVLMLRDGGVQMLGTRDEVFAALRKASVMPAGAPTPLASVKARE
>NZ_CP051487.1|WP_168757604.1|2253280_2254621_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MQMSQHTEMIQADPRSVVDLDVGKPARWGVWLVLAGFGGFLLWSWLAPLDAGVVATGTVKVTSNRKAVQHLSGGTVEAILVREGDVVTKGQELVRLDSLRAAAEQGAVGAQYIVSKTVENRLEAERDARNVVIFDPELLKRFGNDHRLVAAMDLQQRLLDTRRAGLAGEISILEENLAASQVQLKGLQQVYGARTSQINFLNQELQGTRVLAAEGYVPRNRLLELERSNADLSAGQAENLNNIARVRSQATEIKLRILQRQHDYLKEVESQLTETAKENTTLADRLRALDYEVTHTVIRSPIDGMVQSLSIATVGGVIQPGFKIMEIVPVNEPLQVDAMIPVQAIDKMVPGLPVDIAFPAFNHAQTPNIPGRVKTISADRLLDEESKQPFYLAQVEVTSDGMRLLGSNHIRPGMPASVTIKTGERNLMSYLLKPMLERVDSSFKEQ
>NZ_CP051487.1|WP_033042802.1|2251950_2253279_-|TolC-family-outer-membrane-protein
MDRHCIVFCLLGLSLPASAMDLKQAWDLLQYQGPIYRAAVHEKAAGEENRAIGKAGLLPQVNASAYDNKVNGTQRQNGLDRDLDYDSKGANVRLRQPLFNKQKMAEYRQGKQRADYSVAVFDAKSQDAAVRLAESYFDVLLASETILLAKSKLNAFEEQLASAKRRMELGAGTITDIDESVARRDLAEAELIEAQDNLVNARRKLEEYIGEPPESLTTLQPNFATPPLLPSNLQDWLVKAQADSPLIHARRHSSALAEEEVKRAKAGHWPTLDFVAGYTAGDSQSISELNQRNRYSSIGLEVNFPLYSGGGTSALARQASANSYKAMDELDATRQEVITGTTREYQGVQSGAQRIHALEKAVASNERSLASTRKGFKEGGTSTNSDVLNAEELLFVARHDLFEAKLRYLMSRLRLASSVGSLGDDDIDHINNYLGPELLVTN
>NZ_CP051487.1|WP_168759151.1|2250818_2251718_+|LysR-family-transcriptional-regulator
MNRYLRTLPPLETLITFEAVGRHKSFTGAAGELFLTQSAVSKQMRQLEDGMGVALFERKPRGVALTGAGEELLMTVNMLLATMYQSVTRIRNVHQSNAVSVLATHALAQFWLFPKLIEFNKAYPDIAVHVHAINEFDEASLNDFDVGILYGSGQWPSLDSDFLLPEIVYAVAHPSLDVSGIKTLEHLVQANLVQIDTCAWQCLDWRQWFGHFGIDYVARDKAPVFNQLTLAYRAVQQGMGIGLAWTFMADEALAKGELQRVTPFECVTGNGEFLVSLKHRKRSACAEIFCQWLLGSLGD
>NZ_CP051487.1|WP_168757603.1|2249748_2250693_-|DMT-family-transporter
MMNSGIVFAILAGAIWGGVIIGPSLLPEFNAVLISSVRFSLYGLISLLLALPIASSLLARLTRNDVFVLLRLSLTGNVLNYALLGASVQLSGVTAAALINGMMPVAITFLGRGDPGSLPLSKLKLPLLLVFLGIVSVSLEHSGAPAASTSLSSRLLGLACGFSAVVCWSWYATRNARYLKQSHFNSSEWSTLVGIVTGIVAVVFGIAALMLFPNLVPTQVESSRWMALLWVCLFLALCGSWLANGLWNACSRRMATSLSGQMIVFETLFACVYGFLFSQRVPGLMEVISIVLLVVGVVWAAKRHRVVPVKHAQP
>NZ_CP051487.1|WP_168757602.1|2248849_2249677_+|phosphonoacetaldehyde-hydrolase
MHYQQPSQLQAVVLDWAGTVVDFGSFAPTQIFVEAFAEFGVAVSLQEARGPMGMGKWDHIRTLCNEPQIADRYHAVFGRLPTDDDVTALYERFMPLQIEKIALHSALIPGALETINGLRDKGLKIGSCSGYPAVVMEKVVELARQNGYVTDHVVATDEVPNGRPHPAQALANVIALGVSDVAACVKVDDTWPGILEGRSAGMWTVALTCSGNALGLTYDQYKNLSADELSEARSRITRMFEGSRPHYLIDTIVDLPAVIEDINARLARGEVPQCC
>NZ_CP051487.1|WP_020800152.1|2247890_2248763_+|LysR-family-transcriptional-regulator
MYQYHKWLRSFHAVAKTGSFTLAAEYLSVGQPTVSEQVTALEKKFSVELFHRRGRIVEMSSAGHKLYAITQGLFGQEDEAVQLLQSFKQRKTGMLRLGAVSPPIAMNLTYELMQRHPDIELETSFSPEKETLDRLFNFDIDVAILALSEFDQRFDTQLYRRYPIIAVVRDDHPWAAQKAVHVEQISDEKWVLREKSSRTRQLVEESCDRLDVDLNCVMQLNSREAIVHAIAKGIGIGFVSAVEYAETPGTKPITFVDHPFFIDYHLCCLGIRRNRPMIAELFDSSPIPAT
>NZ_CP051487.1|WP_033044693.1|2246540_2247836_+|MFS-transporter
MNRAQALPSLAVSTSSFRVAQWRMLLAAMFCYLFFYTGRQTFGFAIPGIQAEFGFTKEHLGWASAAMLWAYAIGQAINGNLADKFGGRRIMTAGAVLSCAANWITSFAGSFVALILPWGINGYFQALGWAPGSRLISNWWSTGERGKVYGFYVFAAGCASVLSYVTSIVVLEVLQLEWRWIFRLPVLLMLAGGIVFYLVARERPQDMGFEPLADTGVANADDKNHEVAHGELETSAQRYKAVLKNYRLIIAAISLGFQNAARYGLIVWVPVHFLGADWKSGDSLIDPKWITVALPVGMAIGALSNGWISDKLFGSKRYLAIMLYMFLGAGTSLWMWSLAPHSAVGLVALFLCGFFVYGPASSFWALCPDLVGAKRAGTATGIMNFSSYLFAGLAEPLIGSMLDSTGNTSLIFIVVTSACLCSAAVALFIRR
>NZ_CP051487.1|WP_168757601.1|2245264_2246356_+|iron-containing-alcohol-dehydrogenase
MIARFHNPVDTRLGYNSLVELASITENQKVALVIFPEARGLGLVDRIQDLLGERLIYIVEDVQPNPDVAQLRGTYERFWQEAGDCQTVIAVGGGSAIDTAKALIVGTQSGRFDELVALLATGKPFVPAHSKALIAVPTTAGTGSEVTPWATIWDTEGQKKYSLHLDCTWPKVAIVDPGLMLTVPAGVTVSTGLDALSHALESIWNINANPVSDTFAISAIEDILECLPLLRHDLGSKELRSRMALAALKAGLAFSNTKTALAHSISYEMTLRHGLPHGIACSFTLPLVLGLAWGRDEARDRVLKRVFGKDLDEAQAQLRNFLHSLDVKTEFADYGVTQEEAREMIEFALQGARGKNFIGAHAA
>NZ_CP051487.1|WP_168757600.1|2244542_2244965_-|nuclear-transport-factor-2-family-protein
MADFLRCFASEFAALDGSNLHNLKHLYSHDVRFSDPLHEIQGLTALEEYFTELYANVSELGFTFHGYDQVQDGAGYLRWTLHYRHPRLRHGQLIEVVGCSHLLWHKKVYQHRDYFDAGALLYEHLPLMGSAIGWLKGRLA
>NZ_CP051487.1|WP_168757606.1|2268689_2271497_+|multicopper-oxidase-domain-containing-protein
MDTKARYPFKWSGLLTPLSIALSMTLSTGNLRASPIDDERQPQPTDPSAYHDEAADKAAALNAILTMPDANMDSFDLPGGVKGSKDTTRVENILPPTLQTSFNYPTNGKPSPLYGALPFTQPLVLFEEFGLEKLDPTTPAALLPFPPAAIGPLPQQDPTSVARSAPPSAALDAFLRQPGLTPYPSQYSNVVDRNPWQKQIEFFLNRRIGSSAEGRPPGKGWSHQRWNEFYPQVAYKTVQTGARLNTGLRDSRQMHRYAMGEFGPGGLYYNVAGVPATAGTSKGAEPRFHPKMPVQKHNSLWTFDGTLPPKLLMVRYGQPVLMRHYNGLPIDPSANMGFGLHTISTHEHNGHVPAESDGYANAFFFPGQFYDYRWPIQLAGYDSINTKAEDPRAAFPCSPGETLWTNDMSPGRKTCENGTIKIRGDWRETMSTHWFHDHMLDFTAQNVYKGNAAMMNYYSALDRGNESVNDGVNLRLPSGSALPWGNRDYDVNLLFADKAWDKNGQLWFNPFNTAGFLGDQVLVNWKWKPTLDVRARSYRLRMLNGSVSRYFKLALVREIKGTTGEFPGPVGSGVSYARVPFHMIANDGNIMEHSVPFDGTMDLDADGDKQNHNAILPTLGIAERFDIIVNFAKNGIKPGDKLFFVNLQVHEDGKGPEEPASLADVLSEKYRAILKQTSKGPKWEEGDPAVGKVLQLNVKAYTGQDLAMDPAAYEPAKPGKAEGLVMIPLKIHRDNLADQALLAKARHRTFTFGRSDGTDEAPWTVKTDGGFGFQMDPRRLSASAQLASGPTDAGATGFGTLEVWNIKLGGEGWSHPVHVHFEEGIILNRGGKAPPEWEKWARKDVYRIGPEKDGLDNVEIAISFREFAGTYMEHCHNTQHEDNSMLLRWDVEKPGQFQLMPTPLPSWDGVRYVNSAALPTFRTGDGNGPQAVAKP
>NZ_CP051487.1|WP_168757607.1|2271732_2272941_+|MFS-transporter
MSSESPRTGNDRSGIPRTIWALGFVSLFMDLSSEMVHSLLPVFMVTTLGASALTVGVIEGVAESTAMLIKVFSGAISDFIGRRKGLLLLGYGVAALSKPLFPLAHSVEVVFTARFLDRIGKGIRGAPRDALVADMSPPPIRGACFGLRQSMDTVGAVLGPAMAIVLMLWLADIQLVLWFAVIPAIVAVALIFVGVKEPTPVSRERTFRSPIHWRVLPGFSRGYWWVVVIGGVFTLARFSEAFLVLRAQQTGLSVAWVPLVMVVMAIFYALSAYPAGWLSDRISRTKLLCMGMGLLILADLVIAGSGSIITMMLGVALWGLHMGFSQGILASLVADTAPLDLKGTAFGIFNLVSGVCMLIASVLAGAIWQGMGSVNTFLAGALLAATALFLLIAVERSRGRAS
>NZ_CP051487.1|WP_168757608.1|2273275_2274772_+|DUF1254-domain-containing-protein
MSGTSRALGQMLPIAMAALLGTAAPVVLAQAEAVPSQALVLPSGPAENTRITEAYARLVARDAWFWAWPMVNMYNRRLAYAKAPEQGLIGGTLPIAPHNRLTMLSDYIKPDQRSIACPNQDVVYGAGYLALNDSPVVIQIPDFGKRFWVIQLSDLRTESINGLGVMYGTKPGFYLVVGPNWQGTVPKGITRVIRTQSNAAFVGPRVFQDDTPQDRQAVQEVIQGINVYPVAEYDGTLKRQDWRKLPVFPKRDDARGETRWVRPDVFFDQLPAVLDLVPAVAGEAARYAQVLAVIAAAQKNPELKQAMIDEAEKADRELIDPLLQFRNWGIELPHHWSTITNGAHFGTDYFTRTAVAKSNILVNAPNETRYFYQDLDAAGMRLNGASAYTVTFAKGQLPPVKGFWSLTAYDSAHFFVPNPLNRYSLGTKNQDLKTNADGSLTFYVQAESPGADKESNWLPAPKGADFSLFLRAYWPDDAITKGLWTPPAIEKRAVDTSS
>NZ_CP051487.1|WP_168757609.1|2275304_2275853_+|cytochrome-b
MAKVESYTSTAKWLHWGMALLWIGAWFIGILATHWRDEFNAHHELTFLHKAMASTLLFLIVVRIAWRLTHPAPALPAAMSPLMKRGAFFGHLMLYAIALIGLPLSGWYWSSVADKPILVAGLFQLPPMVGPDQSLYDLAKSIHTYVAWLCGALVGGHALVALTHHFVEKDEVLKSMLPGPNS
>NZ_CP051487.1|WP_168757610.1|2276085_2276436_+|helix-turn-helix-transcriptional-regulator
MTNRTSTRSRAIDAAIDSLDGAFFKALCEPSRVAVLKRVMQLGRADIGEIAEGLPQERSVVSRHLQVLLEAGIVRATKVSRQMFYEVDGPAVVTRLEAILQHMKSLAPFCCPGAPE
>NZ_CP051487.1|WP_168757611.1|2276474_2277545_+|NAD(P)/FAD-dependent-oxidoreductase
MNITNEPKDVIVIGAGQAGLACGWHLRQQNLSFLILDAESQPGGNWRNYYDNLRLFSPAAYSSLPGMPFPAEAKHYPLRDEVVRYLEQYADAFQLPIRQNIRVQSVSREDGLFLLQASDGQRFYSKALIVCTGGFNQPFIPDIQGLESFRGQRLHSADYRNVDGFSDQRVVVIGAANSAVQIAHELAQVSSVVLATRKSIRFFPQKILGVDFHAWLKWTGMEKTRWLNDQSTPVLDDGTYRRAIKQGLFERKPMFTEVTSTGVIWADGQYTDVDSLVFATGFRPNLGFLAGLHVAGNESLTQRNGKAEHVPGLYFVGLPKQRNFASATLRGVGPDASHIIPGLMRFIHNASYPVLA
>NZ_CP051487.1|WP_168757612.1|2277597_2278815_-|MFS-transporter
MSTPVVTLPEQIHLPIDRSRLVWALGLTQILAWGSSYYLPAVLASPIAKETGWSITSVVGGLSWGLLIAGASSPAVGRQIDRHGGRSILAASSLLLALGMLLMGLAGNIATYYAAWTLIGVAMAAGLYDAAFSTLGRLFGEEARTSITGLTLLGGFASTVGWPVIAGLESWIGWRNACFTIAAAHLLIGLPIHALLIPGSTKQPPHPVIVESPNVSELRPRATNQLFLLIAAMLTVLALVVSGISVHLLNVLKQLGIATAVALAIGMVIGPSQVLARVAEFSIGRNLHPTWSARAGVLLCLVGLGLLISGLPWLAFVAIALYGAGNGILTIARGTLPLALFGPQGYGARMGLLARPVLVAQACGPIAAAYVLDSFGASVLLSVMCGFLLLCFIATWRLPITQKGR
>NZ_CP051487.1|WP_168757613.1|2278938_2279436_+|MarR-family-transcriptional-regulator
MTKRKNDQLTQDSEDLYEALNQLVRVHQFRDRDRICCYDVSVTQCYAVETLVKKGALRLQVLAEEMFLDKSTASRVIDALERKGYVSRVEDDEDRRAVRIQATEAGRELYEKIKADLIAEERAMIEHLSAEARQGALSLLRQITRATEIRCGLVSECCPAVKSKD
>NZ_CP051487.1|WP_168757614.1|2279500_2280004_+|N-acetyltransferase
MRVRLAEPKDTVSIAAIYNQGIEERSSTFETTPRSSADMLDRINSMERYPVLVMVDEADQVVGWAGLSRYRARTCYDGIADFSIYLDRSVRGQGLGKQLLQSLLEEAKARGFWKVLSRIFTFNHASLALCKACGFRQVGVYEKHACLEGRWLDCAIVERLFPVNQPV
>NZ_CP051487.1|WP_168757615.1|2280018_2281374_+|FAD-dependent-oxidoreductase
MDNNHLPVGIIGAGPVGLAAAAHLLARGITPLILEAGPEAGSSIEEWAHVKMFSPWQFNVDKEAAKLLLADGWTPPPQNEYPTGRELLDRFVRPLAGLEQIKRHLQLNTRVLAATRVGQDVMTTQGRSAAPFLLRVAGPTGEQDVLTSAVIDASGTYLTPNWMGAHGIPALGEIEHAAHIAYGIPEVLGRARNRYANKSVLVVGGGHSAFNALQDLVRLIQEAPQTRVLWAIRGNSLERILGGGANDQLEERGKLGLKIRQLLNDGVIELFKNVAIDQVVGNGQGLVVRAGDQILPPVDQIIVATGFRPDMSLLAELRIALDPATQSAVLLAPMIDPNAHSCGTVRPHGAIELAHPEEGLFIVGMKSYGRAPTFLLMTGYEQVRSVVAALAGDWDAAKRVELILPETGICNSDFDEVDDRLKASANQTSCCGTGETILEAAPRTSPGCCKA

Crispr_ID: NZ_CP051487_3

• CRISPR_ID: NZ_CP051487_3
• CRISPR_location: 2704180-2704277
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_3

Consensus_repeat	Method
AACTGTGGGAGCTGGCCTGCCAGCGA	CRISPRCasFinder

spacers of NZ_CP051487_3

>3.1|2704206|46|NZ_CP051487|CRISPRCasFinder
TGGCGGCCTTACAGCCGACCCAGCTCCTGCAGATGTACCCGATCCA

CRISPR arrays and Neighbor proteins around NZ_CP051487_3

CRISPR arrays

The CRISPR arrays of NZ_CP051487_3

>merge|NZ_CP051487|3|2704180-2704277|CRISPRCasFinder
AACTGTGGGAGCTGGCCTGCCAGCGATGGCGGCCTTACAGCCGACCCAGCTCCTGCAGATGTACCCGATCCAAACTGTGGGAGCTGGCTTGCCAGCGA

>NZ_CP051487|3|3|2704180-2704277|CRISPRCasFinder
AACTGTGGGAGCTGGCCTGCCAGCGA	TGGCGGCCTTACAGCCGACCCAGCTCCTGCAGATGTACCCGATCCA
AACTGTGGGAGCTGGCTTGCCAGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_168757848.1|2711711_2713058_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase	unknown	unknown	gnl|CDD|366234
NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein	unknown	unknown	gnl|CDD|182242
NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin	unknown	unknown	gnl|CDD|182242
NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein	unknown	unknown	gnl|CDD|380025
NZ_CP051487.1|WP_020796385.1|2698088_2698637_+|general-secretion-pathway-protein-GspM	unknown	unknown	unknown
NZ_CP051487.1|WP_168757844.1|2697556_2698102_+|pilus-assembly-protein	unknown	unknown	gnl|CDD|225707
NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers	unknown	unknown	gnl|CDD|185106
NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE	unknown	unknown	gnl|CDD|236678
NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome	unknown	unknown	gnl|CDD|239266
NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein	unknown	unknown	gnl|CDD|227133
NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259934
NZ_CP051487.1|WP_020796386.1|2698636_2699155_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF	unknown	unknown	gnl|CDD|182210

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.24999e-39
NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	2.2669e-17
NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.42228e-24
NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein	gnl|CDD|182242	PRK10101, csgB, curlin minor subunit CsgB; Provisional.	1.19375e-17
NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	3.35631e-09
NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin	gnl|CDD|182242	PRK10101, csgB, curlin minor subunit CsgB; Provisional.	7.57355e-08
NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein	gnl|CDD|380025	pfam17803, Cadherin_4, Bacterial cadherin-like domain. This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.	3.28422e-08
NZ_CP051487.1|WP_168757844.1|2697556_2698102_+|pilus-assembly-protein	gnl|CDD|225707	COG3166, PilN, Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion].	0.00305016
NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers	gnl|CDD|185106	PRK15184, PRK15184, curli production assembly/transport protein CsgG; Provisional.	1.09092e-91
NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE	gnl|CDD|236678	PRK10386, PRK10386, curli production assembly/transport protein CsgE.	2.01299e-62
NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.02964e-35
NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	4.38227e-168
NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome	gnl|CDD|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.04887e-41
NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein	gnl|CDD|227133	COG4796, HofQ, Type II secretory pathway, component HofQ [Intracellular trafficking and secretion].	3.57113e-48
NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein	gnl|CDD|259934	cd13866, CuRO_2_BOD, The second cupredoxin domain of Bilirubin oxidase (BOD). Bilirubin oxidase (BOD) catalyzes the oxidation of bilirubin to biliverdin and the four-electron reduction of molecular oxygen to water. It is used in diagnosing jaundice through the determination of bilirubin in serum. BOD is a member of the multicopper oxidase (MCO) family that also includes laccase, ascorbate oxidase and ceruloplasmin. MCOs are capable of oxidizing a vast range of substrates, varying from aromatic compounds to inorganic compounds such as metals. Although the members of this family have diverse functions, majority of them have three cupredoxin domain repeats. The copper ions are bound in several sites: Type 1, Type 2, and/or Type 3. The ensemble of types 2 and 3 copper is called a trinuclear cluster. MCOs oxidize their substrate by accepting electrons at a mononuclear copper center and transferring them to the active site trinuclear copper center. The cupredoxin domain 2 of 3-domain MCOs has lost the ability to bind copper.	2.86618e-60
NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	6.05077e-17
NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF	gnl|CDD|182210	PRK10050, PRK10050, curli production assembly/transport protein CsgF.	4.61228e-32

Protein sequences

>NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers
MKKIIALGLMLAALQGCSLREPMPAEQDSKTPTLTPRASTYYDLINMPRPKGRLMAVVYGFRDQTGQYKPTPASSFSTSVTQGAASMLMDALQASGWFVVLEREGLQNLLTERKIIRASQKKPNTPVNIQGELPPLQAANMMLEGGIIAYDTNVRSGGEGARYLGIDIAREYRVDQVTVNLRAVDVRSGQVLSNVMTSKTIYSVARSAGVFKFIEFKKLLEAEVGYTTNEPAQLCVLSAIEAAVGHMLAQGIERRLWQVAGDNSQPAQNETLDRYLTQNRVVPEGEGEDE
>NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF
MKAKTFLQRAGGCMLGLGACAMVQGTELVYTPVNPSFGGNPLNGTWLLNNAQAQNDYDDPDLKDRTSAAGTSALERFSAQLQSRLLGQLLDNISTGNTGSLSTDAFIVDVVDDSGALTINVTDRATGEVSEIQVNGLAP
>NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE
MKRFCLAMILLLSTCVTWAAEEDEMLGFIVDDTISHIGHEFYYSFSERLRATSPMDFNLVVRERPSARWGSLVTVEFQQRLVYRRFLPPNTVELKDEAYAAADWVRGQIVQRKLEALLQDTTDLERDEL
>NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein
MAAFIPSGKPAAQGGFTYLGVLFLIMVMGMGLASAGELWSTASRRDRERQLLWVGTQYAQALRSYYRSSPGLAQYPKELADLLQDERFPSAKHHIRQLYPDPIGGGEWFLMRGFDGRITGISSSSTDKPLKQADFPSQWSDFNGMASYKDWQFVAEKAFLDGTSGPAKGQSAVPEGLQP
>NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein
MRRERGFTLLELMVVMAIIATLMTIALPRYFNSLEASKETTLRQSLSAMREALDHYYGDTGRYPDSIEQLVEQRYLRNPPMDPIVERKDAWVLVAPPDGVAGGVADIKSGATGRARDGSLYSEW
>NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein
MNASQRGFTLIEVVVTLSLIGLLAGMAAPLTETVVRRGKEQELRTALYQIRDAIDAYKRAFDAGYIEKSLNSSGYPPNLQVLVEGVRDVRSAKGAKFYFLRRVPHDPLAPVKRDDEGGWGLRSYDSTAQNPREGQDVFDVYSKARGKGLNGIAYREW
>NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein
MNKSRLLMSLCLCAGLAACSSAQVAKEEASELIEQGQYEAGLARIEEGLRENPRDTELHIALNSARARAITALLTQADMDRTQRDFASARMGYGRVLTIEPNNRRAQDALRQLEHMRSLDEKLELARGDLRRGDIYGAERQVRQILELDPNNEGALELQGNIRLVQSRNVVAYPQLRTKLDKPVTLEFRDANLKTIFEVLSQVAGLNFIFDKDLRPDMKATIFVRDVRIEDAVALLLQQNQLHQKVVNENTLLIYPDSPQKLKDYQELVMRTFYLTSIDANTALNMVKTMLKTRDVFVDERLNTLTMRDTGDAVRMAEKLLQSQDQSNPEVVLEVEVMEVATQRILDLGLQWPNTFGVVNSDGSAVTLLDQLKGINSSRITIQPSPQAKINAQDKDINTLASPVIRVSNREQARIHIGQRVPIISATSVPSTQGPVITESVTYLDVGLKLEVQPTVHLNNEVAIKVALEVSNATPLEPTRQGTIPVQVDTRNAQTTLRLHDGETQILAGLMRNDHGSTGNKIPGLGDIPGLGRLFGSNKDDVSKSELVLSITPRIVRNLPYQSPSDMEFTTGTETSMHIQAPDRSKVEVEEVKANGMGAPIATTVTVGKP
>NZ_CP051487.1|WP_020796386.1|2698636_2699155_+|hypothetical-protein
MNNKRAVGWVAFLGVAAALTWVPEYFKQADDSDVEVAAVATPVKGKQRGALPAAQASAAPVAIKDLSPAGDLFAARSWKAAPTLASVTEQPVNVAPVVQVPTAPPMPFQFIGRMDDRTDLQVFLQNGEKIYVVRKGDVIDETWKIEGISDLELSLVYLPLHLSQTLSVGSAQ
>NZ_CP051487.1|WP_020796385.1|2698088_2698637_+|general-secretion-pathway-protein-GspM
MQIPRLIVHEYLQSLGVPGLAGLALLVLALAYGLFGLLPDWQALQHLSQQTQDAREYLAKVEEGSIAAPVVPQRQLDDFRSKLPTQPQATVAIDKIYALAAQERITLSRGEYSLGIDPKTHLARYQILLPVRGSYPQLRRFMHALLGQLPAVVVEDLELSRKKIADTDLNGRIRMTLYLSRS
>NZ_CP051487.1|WP_168757844.1|2697556_2698102_+|pilus-assembly-protein
MRPLMLDFQPRRRSSPLGWSLLVGGVVLALICIVIQQQVSGEAEQQQGHLQTTQRVLTGDTGSKVSLTPAETREQAQNLAEMRKVSQQLRRPWERLFATLEAMPRDNIALLTLTPDARKGQVRISAEARDLDAMLDFHRRLEACDELSDVSLLSHEIVANVPEHPVQFNLSATWEIGDANP
>NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase
MTYYSPERKAALLKMLLPPLSLTVAEVCRREGVSDVSMYLWRKMANQGSKVPDDILLSDKWSAEARFAAVLETASLTQLELGEYCRRNGLYPEQLNAWRQACISGQEAVQAQKMADHEQTRKDKKRILELERELRRKDAALAETAALLVLRKKPQRLLGDRRRGQLTSLPERQLLVGWLIEAIVAGARKIRACQEVGLSLRTLQRWTQPQELQADARTTTLRPKPRNALSEIERHAIVALCNSPTYAHLPPSQIVPRLADEARYLASETTFYRVLRAAGQQHHRGRSRRPRRVVMPTTHAAEKPNQVWSWDITYLPSPIRGKYYYLYLIEDIYSRKAVGWEVYEEESGEKAAALLQRSVISEKCLREPLVLHSDNGAPMKSVTLLSKMYELGITPSRGRPRVSNDNPYSESLFRTLKYCPQWPLEGFASLDAARTWVRDFMRWYNTEHRHSRIRFVTPSERHRGQDHQILVLRHQLYERARQKTPERWSGKTRNWEPIGTVLLNPDRVQQTGKKAA
>NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin
MFKLTPLTAAILVIVSAQALANDSVSTQNQFGDTNIANVTQTAAPMSSATQNQSGTGNDAASVQDNATSTIEQNQSGNYNAGYAEQLFENNSSIIQNQSGDTNISHASQSIGIGGGQVLQQQEGTGNFSFIYQDSQENTTGKTYQYGDSNEANIEQIQVGTANNAVIIQYGTANYATAEQINHMNGQIDINQSGGTNYAYGDQRNGEGGNLTINQYGDGNGSEVWQDTQVASKTTIDQNGQTNEAIVDQSFGDHNVAQVIQVGDLNAIYADQFESMGSTVTLNQQGIGNIHFTYQTGTDHVLNATSTGNDNKVYASNWKGPATQMGGQFGTNQRATVNQNGNGNVANFTQKNTGHIMTTNQTGYGNKTTVTQADSYNELYFDQNGTDNILIADQRGTNNLAQGSSTGTHNTTDVNQEGSSNQAFTTQLYGEDNMITIKQTDTMNVAYVTQGGTGNIANVDQSGMTQMANVQQFGSANSATVLQK
>NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein
MKTSTAALLCLLLLCSSAGVRADDLMENDDIAPGVDLGELPPPVGQQALIDQNGQANVALLQQNGQSLLGQIVQSGSNQEAYILQQGSDLMALINQQGSGNAASITQTGSHNRAQISQNGNNNDASIVQAGTGQQSAVTQAGNGMSVSVTQYR
>NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein
MNKWPRFALNALGLTLSLSGSAFAQLAAVDPGPYTFATGKFPLWYQDNNLLSMELCQSRAVSSRVPSTPGAPSYMCILLPEPGIFDDTLPMVFPDNWPPEAFWFLAETAIPDNAAGYGVDAYVAGIEAAFASENPVDGDQASFARIRIRVNIPIAGTYTITHPYGVEVVNVTAPGRRAINITRDIGIGAPGNFSGAVNGDIGPFLRSVNGPYTEVNPDTGAIETYVGDPNLTEAVTGSPNNTNFLRIQGPAGTIETSLFNLSGKVLDNRAQTPVEVSRATYRRTSSGPGTSSTRVEVFGKSVNGSSLCFRETVALVPGPPQTPCLTSMLGDNTGLFFGHRLTGTAVPPVVVLTATDPTGATRPTAVSSKVSDVVKVQTARYSWDNHSLLIAATSSDEVVVPDMVAQGYGRLTKSGTLQTLTVADLPQPPATVTIKSASGGSDTEPVVVVGTAPDTGENKAPIAVADSGSTSFGIPITLSLLTNDSDPDGNTPLSITELTQPATGQGTVALSGTTAVVYTPPAVVTVPLTTTFTYKAQDIKGLASTAAATVTITVAPNQPPTAVADAAATLGVSIPINVLANDTDPEGNVPLAVASFTQPPTGRGSVTSNGTVLTYNPPATVTTAFTTTFNYFARDSFGAVSTAPATVTVQVSPRPAAETFAVTAATVTARSNNRFNWDFTGTSSVTTGNTITVQVTTPTGLVTLGSTTVPLTGRWRLTVSNSTTVIPSANPTATITSSQGTVRTVQVISN
>NZ_CP051487.1|WP_168757848.1|2711711_2713058_-|hypothetical-protein
MHPLLSKTAIALIVSALAQGAAQAALFAVDPGPYLPDNGGFASWYQDSHGRTLDLCLSKAVSSRVPSAPGAPTYMCNLLPAPGVFDDTQPVVFPTNFPDEAFWFTGDGAIVDAARGIDLGYVSAVEAAFAAEEPKEGDQVSFARIRIRVDVPTPGTYVITHPYGVDVFNVDTPGRRAINMTRDIGIGSPKTYDGALKGDIGPFLRSVNGPYTETNPVTGQAEQFVGDPNLSEAFTGSPFNTNYIRIEGPNGLDLRTTVMAISGKLSTVVRPTPMISERSTYSRKAGESAPVAQQDVFVMAPPPPATVTLDSNSPVLNLTEANTTGHWYAQSSTNPTLPSSLQVTADNHLAIPSSTPTTLSMPLTDLVVISQAQYSLNSGQLTIVASTSDETSPPVLTATSGTGAAIGALSGDGAEKILSTGITPIPPAKVTVTSSNGGTDTEEVVIVQ
>NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase
MTTLAKTLASDQGEVRLSSRKQPFNLLRWFSLISMAVIGTVAVALGSVSTKFVITESVQRDALLTSQFIQAIASAEVRHVSIPNVRTMGELLDPRKDRDFPDVDPMARANARGEFLDHIEHLPDVILANIYAPDRMIIWSTNPALMGTTIHADEDLDQAFALKTPVSASYHDVDKARMEQKFVAPPEYIFIENYIPLFDAEGKNVTAMVEIYKEPKDLINRMERGLVLIWMATALGGGLIYLGLYWIVRRAAILLATQQKQLIVNETFVALGEMSSAVAHSLRNPLATIRSSAELALEFDSGPAHKNINDIIGQVDRMSKWVRELLQSLRPLNDDVEPVNLVAALHDSLMAFEQQIIKGRVNVLFEPKGTPMVLSQQVQLTQILNSLLANALEAMDEGGTLAITMAPVDAQRVRVVVSDTGKGMTEEQRLMAFRPFFTTKRGGLGVGLVLVKRIMERFGGAVALESREGEGTHVSLTFKRVP
>NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein
MDTKARHPLKWFGLLTPLSVALAMILSTGTLRASPIDDERQPEPTDPSAYYDEPEDRAGALNAILTMPDANEDAFDLPDGVKGSRDTERVENVLPPAMQTSFNYPTNGKPSPLFNAQPFTQQLLLFEEFGPEKLDPTTPAAPLPFPAAAIGPLPAQDPSSAARSAPPGPALDAFLRQPGLTPFPSQYANVVDRNPWQAQIEYFLNRRIGSSAEGRPPGKGWSHQRWNEFYPQNAYKTVQTGARINGGLRDARQMHGYAVGEFGPGGLYHNVAGVPATDGTAKGVDTRFHPNMPVQNHNSVWTFDGTLPPKLLMVRYGQPLLMRHYNGLPIDPSANMGFGLHTISTHEHNGHAPAESDGYANAFFFPGQYYDYRWPIQLAGYDSINTDAHDPRAAFPCSPGETLWTNDMSPGRKTCENGTIKIRGDWRETMSTHWFHDHMLDFTAQNVYKGNAAMMNYYSALDRGNESVNDGVNLRFPSGSALPWGNRDYDVNLVFADKAWDANGQLWFNPFNTDGFLGDQVLVNWQWKPTLDVRARSYRFRMLNGSVSRYFKLALVREIKGTGGEFQGPKGSGVSYARVPFHMIANDGNIMEHSVPFDGSMDLDADGDKQNHNAILPTQGIAERFDIIVNFAKNGIKPGDKLFFVNLLVHDDGKGPKEPVSLADALSENYKAVIKQTSKGPMWDKGDPAVGKVLQLNVKPYTGQDLAMDPAAYEPAKPGKAEGLVMIPLKIHRDNATDKALLAKARHRTFTFGRSDGTDEAPWTVKTDGGFGFHMDPRRLNASAQLASGPTDAGVAGYGTLEVWNIKAGGTGWSHPVHVHFEEGIILSRGGKAPPEWEKWARKDVYRIGSEKDGLDSVEMAINFREFAGTYMEHCHNTQHEDNSMLLRWDLEKPGQLQLMPTPLPSWDGVRYVNSAALPTFRTGDGLGPKVTVKP
>NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome
MNREGVDMKLPTARAQALGMHLVLILVTGLLASQLVVSNQAASTPAAVSPASVSESATPWGGDYFPNTLLTDQDGRQVHFFDDLIKGKVVVINFIFTSCSDSCPLETARLRQVQKLLGDRVGKDIFFYSISIDPLSDTPAVLKAYAQRFQVGPGWQFLTGEFSDVTELRQKLGLFIEGVDNGRTKDHNLSLIVGNQQTGRWMKASPFENPWILADQLANTLHNWKQPSVGESYANAPEIRPPSNGEELFRTRCASCHSLGPMDGQGIGMRSIGPDLVGVTRQRDPAWLNRWIREPDRMLAEKDPIATALFERFDKIPMPNLRLDERSVQSIIEFLQAETDRQQPLLTPLTVGAEEPQHQQAIAAPDKARVQ
>NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase
MQILESPQVPAPVTSATEGKDWRSPFNLVRWFSLASFFIIAGVALGLGYISTRFVVEESIERDSMLTAQFVQAIGAAEIRHASISPNRTMGEMLDPRADAAYPDVDPGARAAARIEFLDHVEHLPDILLATVYALDRTVVWSTNPELIGVRIDNDEELDESFEMKAAVSTSYHEIDEERPEQRLLHEPQYLFVENYIPMFNADKSKVVAMVEVYKEPVDLVERIQRGFRAIWLTTLLGGAVIYLGLFWIVRRAALLLHSQQKQLVANETFVALGEMSSAVAHSLRNPLANIRSSAELAQEIASQTAQKNIGDIISQVDRMSRWVRELLVSLRPVNDDHETVDLVLAIDDTLSAYAPQIQRSNVEVRFTPMTVPPVVSQQVLLTQILNSLFANALEAMPKGGVLSIDVETPASGQVRMILNDTGKGMTKQQQQMVFKPFFTTKQGGLGVGLALVKRIMERFEGSVELTSQEQEGTRVCLNFKVATGGEYGAQHTAGRG
>NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MEHSILLVEDDELLAENIQTYLERKNFEVTVCHSAEDALSQLSTFVPDVVLTDNSLPGMNGHDLIQKLRISAPDLKVIMMTGYGNVEDAVVAMKEGAFHYVTKPVALPELKLLLDKALATDRMERTLSFYQEREAQKSGVQALIGESAPMVYLKGTIAQLLDAERRMANSDLPPVLVEGETGTGKELVARALHFDGPRSKGPFIEFNCASIPSNLVESELFGHEKGAFTDAKDRRLGLVEAADGGTLFLDEIGEMDLILQAKLLKLLEDRTIRRVGSVKERKVDLRVISATNCNLEQMVQQGKFRRDLFFRLRIISIKVPRLYARGEDILLLARHFLASHGKRYGKPHLRFSDQAEELLLNYTWPGNVRELRNMLEQTVLLAQHDTIAAHQLNVCLSLVDEPAMFTHELQPIEPRASHNGTESMNLPEVERDMVRKMLDKTDWNVTKSARLLGLSRDMLRYRIEKLGLARPDKRSW

Crispr_ID: NZ_CP051487_4

• CRISPR_ID: NZ_CP051487_4
• CRISPR_location: 2707168-2707262
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_4

Consensus_repeat	Method
GCCAGCTCCTACAGTAGATCGGGTA	CRISPRCasFinder

spacers of NZ_CP051487_4

>4.1|2707193|45|NZ_CP051487|CRISPRCasFinder
CAGTTGCGAGAGAATGCTCGGCTGTAAGGCCGCCATCGCCGGCAG

CRISPR arrays and Neighbor proteins around NZ_CP051487_4

CRISPR arrays

The CRISPR arrays of NZ_CP051487_4

>merge|NZ_CP051487|4|2707168-2707262|CRISPRCasFinder
GCCAGCTCCTACAGTAGATCGGGTACAGTTGCGAGAGAATGCTCGGCTGTAAGGCCGCCATCGCCGGCAGGCCAGCTCCCACAGTAGATCGGGTA

>NZ_CP051487|4|4|2707168-2707262|CRISPRCasFinder
GCCAGCTCCTACAGTAGATCGGGTA	CAGTTGCGAGAGAATGCTCGGCTGTAAGGCCGCCATCGCCGGCAG
GCCAGCTCCCACAGTAGATCGGGTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_168757848.1|2711711_2713058_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase	unknown	unknown	gnl|CDD|366234
NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein	unknown	unknown	gnl|CDD|182242
NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin	unknown	unknown	gnl|CDD|182242
NZ_CP051487.1|WP_020796385.1|2698088_2698637_+|general-secretion-pathway-protein-GspM	unknown	unknown	unknown
NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein	unknown	unknown	gnl|CDD|380025
NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers	unknown	unknown	gnl|CDD|185106
NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE	unknown	unknown	gnl|CDD|236678
NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225114
NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome	unknown	unknown	gnl|CDD|239266
NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein	unknown	unknown	gnl|CDD|227133
NZ_CP051487.1|WP_168757854.1|2721926_2722307_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259934
NZ_CP051487.1|WP_020796386.1|2698636_2699155_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF	unknown	unknown	gnl|CDD|182210

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.24999e-39
NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	3.35631e-09
NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.42228e-24
NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein	gnl|CDD|182242	PRK10101, csgB, curlin minor subunit CsgB; Provisional.	1.19375e-17
NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	2.2669e-17
NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin	gnl|CDD|182242	PRK10101, csgB, curlin minor subunit CsgB; Provisional.	7.57355e-08
NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein	gnl|CDD|380025	pfam17803, Cadherin_4, Bacterial cadherin-like domain. This entry contains numerous bacterial cadherin-like domains found in extracelullar proteins.	3.28422e-08
NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers	gnl|CDD|185106	PRK15184, PRK15184, curli production assembly/transport protein CsgG; Provisional.	1.09092e-91
NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE	gnl|CDD|236678	PRK10386, PRK10386, curli production assembly/transport protein CsgE.	2.01299e-62
NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.02964e-35
NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl|CDD|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	4.38227e-168
NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome	gnl|CDD|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.04887e-41
NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein	gnl|CDD|227133	COG4796, HofQ, Type II secretory pathway, component HofQ [Intracellular trafficking and secretion].	3.57113e-48
NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein	gnl|CDD|259934	cd13866, CuRO_2_BOD, The second cupredoxin domain of Bilirubin oxidase (BOD). Bilirubin oxidase (BOD) catalyzes the oxidation of bilirubin to biliverdin and the four-electron reduction of molecular oxygen to water. It is used in diagnosing jaundice through the determination of bilirubin in serum. BOD is a member of the multicopper oxidase (MCO) family that also includes laccase, ascorbate oxidase and ceruloplasmin. MCOs are capable of oxidizing a vast range of substrates, varying from aromatic compounds to inorganic compounds such as metals. Although the members of this family have diverse functions, majority of them have three cupredoxin domain repeats. The copper ions are bound in several sites: Type 1, Type 2, and/or Type 3. The ensemble of types 2 and 3 copper is called a trinuclear cluster. MCOs oxidize their substrate by accepting electrons at a mononuclear copper center and transferring them to the active site trinuclear copper center. The cupredoxin domain 2 of 3-domain MCOs has lost the ability to bind copper.	2.86618e-60
NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	6.05077e-17
NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF	gnl|CDD|182210	PRK10050, PRK10050, curli production assembly/transport protein CsgF.	4.61228e-32

Protein sequences

>NZ_CP051487.1|WP_116287586.1|2705432_2706982_-|IS3-family-transposase
MTYYSPERKAALLKMLLPPLSLTVAEVCRREGVSDVSMYLWRKMANQGSKVPDDILLSDKWSAEARFAAVLETASLTQLELGEYCRRNGLYPEQLNAWRQACISGQEAVQAQKMADHEQTRKDKKRILELERELRRKDAALAETAALLVLRKKPQRLLGDRRRGQLTSLPERQLLVGWLIEAIVAGARKIRACQEVGLSLRTLQRWTQPQELQADARTTTLRPKPRNALSEIERHAIVALCNSPTYAHLPPSQIVPRLADEARYLASETTFYRVLRAAGQQHHRGRSRRPRRVVMPTTHAAEKPNQVWSWDITYLPSPIRGKYYYLYLIEDIYSRKAVGWEVYEEESGEKAAALLQRSVISEKCLREPLVLHSDNGAPMKSVTLLSKMYELGITPSRGRPRVSNDNPYSESLFRTLKYCPQWPLEGFASLDAARTWVRDFMRWYNTEHRHSRIRFVTPSERHRGQDHQILVLRHQLYERARQKTPERWSGKTRNWEPIGTVLLNPDRVQQTGKKAA
>NZ_CP051487.1|WP_020796393.1|2703185_2704058_+|protein-involved-in-formation-of-curli-polymers
MKKIIALGLMLAALQGCSLREPMPAEQDSKTPTLTPRASTYYDLINMPRPKGRLMAVVYGFRDQTGQYKPTPASSFSTSVTQGAASMLMDALQASGWFVVLEREGLQNLLTERKIIRASQKKPNTPVNIQGELPPLQAANMMLEGGIIAYDTNVRSGGEGARYLGIDIAREYRVDQVTVNLRAVDVRSGQVLSNVMTSKTIYSVARSAGVFKFIEFKKLLEAEVGYTTNEPAQLCVLSAIEAAVGHMLAQGIERRLWQVAGDNSQPAQNETLDRYLTQNRVVPEGEGEDE
>NZ_CP051487.1|WP_083348794.1|2702735_2703155_+|curli-production-assembly-protein-CsgF
MKAKTFLQRAGGCMLGLGACAMVQGTELVYTPVNPSFGGNPLNGTWLLNNAQAQNDYDDPDLKDRTSAAGTSALERFSAQLQSRLLGQLLDNISTGNTGSLSTDAFIVDVVDDSGALTINVTDRATGEVSEIQVNGLAP
>NZ_CP051487.1|WP_020796391.1|2702349_2702739_+|curli-production-assembly/transport-protein-CsgE
MKRFCLAMILLLSTCVTWAAEEDEMLGFIVDDTISHIGHEFYYSFSERLRATSPMDFNLVVRERPSARWGSLVTVEFQQRLVYRRFLPPNTVELKDEAYAAADWVRGQIVQRKLEALLQDTTDLERDEL
>NZ_CP051487.1|WP_020796390.1|2701813_2702353_+|type-II-secretion-system-protein
MAAFIPSGKPAAQGGFTYLGVLFLIMVMGMGLASAGELWSTASRRDRERQLLWVGTQYAQALRSYYRSSPGLAQYPKELADLLQDERFPSAKHHIRQLYPDPIGGGEWFLMRGFDGRITGISSSSTDKPLKQADFPSQWSDFNGMASYKDWQFVAEKAFLDGTSGPAKGQSAVPEGLQP
>NZ_CP051487.1|WP_033042927.1|2701464_2701839_+|type-II-secretion-system-protein
MRRERGFTLLELMVVMAIIATLMTIALPRYFNSLEASKETTLRQSLSAMREALDHYYGDTGRYPDSIEQLVEQRYLRNPPMDPIVERKDAWVLVAPPDGVAGGVADIKSGATGRARDGSLYSEW
>NZ_CP051487.1|WP_020796388.1|2700986_2701460_+|type-II-secretion-system-protein
MNASQRGFTLIEVVVTLSLIGLLAGMAAPLTETVVRRGKEQELRTALYQIRDAIDAYKRAFDAGYIEKSLNSSGYPPNLQVLVEGVRDVRSAKGAKFYFLRRVPHDPLAPVKRDDEGGWGLRSYDSTAQNPREGQDVFDVYSKARGKGLNGIAYREW
>NZ_CP051487.1|WP_168757845.1|2699151_2700984_+|secretion-type-II-protein
MNKSRLLMSLCLCAGLAACSSAQVAKEEASELIEQGQYEAGLARIEEGLRENPRDTELHIALNSARARAITALLTQADMDRTQRDFASARMGYGRVLTIEPNNRRAQDALRQLEHMRSLDEKLELARGDLRRGDIYGAERQVRQILELDPNNEGALELQGNIRLVQSRNVVAYPQLRTKLDKPVTLEFRDANLKTIFEVLSQVAGLNFIFDKDLRPDMKATIFVRDVRIEDAVALLLQQNQLHQKVVNENTLLIYPDSPQKLKDYQELVMRTFYLTSIDANTALNMVKTMLKTRDVFVDERLNTLTMRDTGDAVRMAEKLLQSQDQSNPEVVLEVEVMEVATQRILDLGLQWPNTFGVVNSDGSAVTLLDQLKGINSSRITIQPSPQAKINAQDKDINTLASPVIRVSNREQARIHIGQRVPIISATSVPSTQGPVITESVTYLDVGLKLEVQPTVHLNNEVAIKVALEVSNATPLEPTRQGTIPVQVDTRNAQTTLRLHDGETQILAGLMRNDHGSTGNKIPGLGDIPGLGRLFGSNKDDVSKSELVLSITPRIVRNLPYQSPSDMEFTTGTETSMHIQAPDRSKVEVEEVKANGMGAPIATTVTVGKP
>NZ_CP051487.1|WP_020796386.1|2698636_2699155_+|hypothetical-protein
MNNKRAVGWVAFLGVAAALTWVPEYFKQADDSDVEVAAVATPVKGKQRGALPAAQASAAPVAIKDLSPAGDLFAARSWKAAPTLASVTEQPVNVAPVVQVPTAPPMPFQFIGRMDDRTDLQVFLQNGEKIYVVRKGDVIDETWKIEGISDLELSLVYLPLHLSQTLSVGSAQ
>NZ_CP051487.1|WP_020796385.1|2698088_2698637_+|general-secretion-pathway-protein-GspM
MQIPRLIVHEYLQSLGVPGLAGLALLVLALAYGLFGLLPDWQALQHLSQQTQDAREYLAKVEEGSIAAPVVPQRQLDDFRSKLPTQPQATVAIDKIYALAAQERITLSRGEYSLGIDPKTHLARYQILLPVRGSYPQLRRFMHALLGQLPAVVVEDLELSRKKIADTDLNGRIRMTLYLSRS
>NZ_CP051487.1|WP_168757846.1|2707419_2708874_-|curlin
MFKLTPLTAAILVIVSAQALANDSVSTQNQFGDTNIANVTQTAAPMSSATQNQSGTGNDAASVQDNATSTIEQNQSGNYNAGYAEQLFENNSSIIQNQSGDTNISHASQSIGIGGGQVLQQQEGTGNFSFIYQDSQENTTGKTYQYGDSNEANIEQIQVGTANNAVIIQYGTANYATAEQINHMNGQIDINQSGGTNYAYGDQRNGEGGNLTINQYGDGNGSEVWQDTQVASKTTIDQNGQTNEAIVDQSFGDHNVAQVIQVGDLNAIYADQFESMGSTVTLNQQGIGNIHFTYQTGTDHVLNATSTGNDNKVYASNWKGPATQMGGQFGTNQRATVNQNGNGNVANFTQKNTGHIMTTNQTGYGNKTTVTQADSYNELYFDQNGTDNILIADQRGTNNLAQGSSTGTHNTTDVNQEGSSNQAFTTQLYGEDNMITIKQTDTMNVAYVTQGGTGNIANVDQSGMTQMANVQQFGSANSATVLQK
>NZ_CP051487.1|WP_020796234.1|2708901_2709363_-|hypothetical-protein
MKTSTAALLCLLLLCSSAGVRADDLMENDDIAPGVDLGELPPPVGQQALIDQNGQANVALLQQNGQSLLGQIVQSGSNQEAYILQQGSDLMALINQQGSGNAASITQTGSHNRAQISQNGNNNDASIVQAGTGQQSAVTQAGNGMSVSVTQYR
>NZ_CP051487.1|WP_168757847.1|2709423_2711676_-|cadherin-like-domain-containing-protein
MNKWPRFALNALGLTLSLSGSAFAQLAAVDPGPYTFATGKFPLWYQDNNLLSMELCQSRAVSSRVPSTPGAPSYMCILLPEPGIFDDTLPMVFPDNWPPEAFWFLAETAIPDNAAGYGVDAYVAGIEAAFASENPVDGDQASFARIRIRVNIPIAGTYTITHPYGVEVVNVTAPGRRAINITRDIGIGAPGNFSGAVNGDIGPFLRSVNGPYTEVNPDTGAIETYVGDPNLTEAVTGSPNNTNFLRIQGPAGTIETSLFNLSGKVLDNRAQTPVEVSRATYRRTSSGPGTSSTRVEVFGKSVNGSSLCFRETVALVPGPPQTPCLTSMLGDNTGLFFGHRLTGTAVPPVVVLTATDPTGATRPTAVSSKVSDVVKVQTARYSWDNHSLLIAATSSDEVVVPDMVAQGYGRLTKSGTLQTLTVADLPQPPATVTIKSASGGSDTEPVVVVGTAPDTGENKAPIAVADSGSTSFGIPITLSLLTNDSDPDGNTPLSITELTQPATGQGTVALSGTTAVVYTPPAVVTVPLTTTFTYKAQDIKGLASTAAATVTITVAPNQPPTAVADAAATLGVSIPINVLANDTDPEGNVPLAVASFTQPPTGRGSVTSNGTVLTYNPPATVTTAFTTTFNYFARDSFGAVSTAPATVTVQVSPRPAAETFAVTAATVTARSNNRFNWDFTGTSSVTTGNTITVQVTTPTGLVTLGSTTVPLTGRWRLTVSNSTTVIPSANPTATITSSQGTVRTVQVISN
>NZ_CP051487.1|WP_168757848.1|2711711_2713058_-|hypothetical-protein
MHPLLSKTAIALIVSALAQGAAQAALFAVDPGPYLPDNGGFASWYQDSHGRTLDLCLSKAVSSRVPSAPGAPTYMCNLLPAPGVFDDTQPVVFPTNFPDEAFWFTGDGAIVDAARGIDLGYVSAVEAAFAAEEPKEGDQVSFARIRIRVDVPTPGTYVITHPYGVDVFNVDTPGRRAINMTRDIGIGSPKTYDGALKGDIGPFLRSVNGPYTETNPVTGQAEQFVGDPNLSEAFTGSPFNTNYIRIEGPNGLDLRTTVMAISGKLSTVVRPTPMISERSTYSRKAGESAPVAQQDVFVMAPPPPATVTLDSNSPVLNLTEANTTGHWYAQSSTNPTLPSSLQVTADNHLAIPSSTPTTLSMPLTDLVVISQAQYSLNSGQLTIVASTSDETSPPVLTATSGTGAAIGALSGDGAEKILSTGITPIPPAKVTVTSSNGGTDTEEVVIVQ
>NZ_CP051487.1|WP_168757849.1|2713347_2714796_+|HAMP-domain-containing-histidine-kinase
MTTLAKTLASDQGEVRLSSRKQPFNLLRWFSLISMAVIGTVAVALGSVSTKFVITESVQRDALLTSQFIQAIASAEVRHVSIPNVRTMGELLDPRKDRDFPDVDPMARANARGEFLDHIEHLPDVILANIYAPDRMIIWSTNPALMGTTIHADEDLDQAFALKTPVSASYHDVDKARMEQKFVAPPEYIFIENYIPLFDAEGKNVTAMVEIYKEPKDLINRMERGLVLIWMATALGGGLIYLGLYWIVRRAAILLATQQKQLIVNETFVALGEMSSAVAHSLRNPLATIRSSAELALEFDSGPAHKNINDIIGQVDRMSKWVRELLQSLRPLNDDVEPVNLVAALHDSLMAFEQQIIKGRVNVLFEPKGTPMVLSQQVQLTQILNSLLANALEAMDEGGTLAITMAPVDAQRVRVVVSDTGKGMTEEQRLMAFRPFFTTKRGGLGVGLVLVKRIMERFGGAVALESREGEGTHVSLTFKRVP
>NZ_CP051487.1|WP_168757850.1|2714982_2717790_+|multicopper-oxidase-domain-containing-protein
MDTKARHPLKWFGLLTPLSVALAMILSTGTLRASPIDDERQPEPTDPSAYYDEPEDRAGALNAILTMPDANEDAFDLPDGVKGSRDTERVENVLPPAMQTSFNYPTNGKPSPLFNAQPFTQQLLLFEEFGPEKLDPTTPAAPLPFPAAAIGPLPAQDPSSAARSAPPGPALDAFLRQPGLTPFPSQYANVVDRNPWQAQIEYFLNRRIGSSAEGRPPGKGWSHQRWNEFYPQNAYKTVQTGARINGGLRDARQMHGYAVGEFGPGGLYHNVAGVPATDGTAKGVDTRFHPNMPVQNHNSVWTFDGTLPPKLLMVRYGQPLLMRHYNGLPIDPSANMGFGLHTISTHEHNGHAPAESDGYANAFFFPGQYYDYRWPIQLAGYDSINTDAHDPRAAFPCSPGETLWTNDMSPGRKTCENGTIKIRGDWRETMSTHWFHDHMLDFTAQNVYKGNAAMMNYYSALDRGNESVNDGVNLRFPSGSALPWGNRDYDVNLVFADKAWDANGQLWFNPFNTDGFLGDQVLVNWQWKPTLDVRARSYRFRMLNGSVSRYFKLALVREIKGTGGEFQGPKGSGVSYARVPFHMIANDGNIMEHSVPFDGSMDLDADGDKQNHNAILPTQGIAERFDIIVNFAKNGIKPGDKLFFVNLLVHDDGKGPKEPVSLADALSENYKAVIKQTSKGPMWDKGDPAVGKVLQLNVKPYTGQDLAMDPAAYEPAKPGKAEGLVMIPLKIHRDNATDKALLAKARHRTFTFGRSDGTDEAPWTVKTDGGFGFHMDPRRLNASAQLASGPTDAGVAGYGTLEVWNIKAGGTGWSHPVHVHFEEGIILSRGGKAPPEWEKWARKDVYRIGSEKDGLDSVEMAINFREFAGTYMEHCHNTQHEDNSMLLRWDLEKPGQLQLMPTPLPSWDGVRYVNSAALPTFRTGDGLGPKVTVKP
>NZ_CP051487.1|WP_168757851.1|2717786_2718902_+|c-type-cytochrome
MNREGVDMKLPTARAQALGMHLVLILVTGLLASQLVVSNQAASTPAAVSPASVSESATPWGGDYFPNTLLTDQDGRQVHFFDDLIKGKVVVINFIFTSCSDSCPLETARLRQVQKLLGDRVGKDIFFYSISIDPLSDTPAVLKAYAQRFQVGPGWQFLTGEFSDVTELRQKLGLFIEGVDNGRTKDHNLSLIVGNQQTGRWMKASPFENPWILADQLANTLHNWKQPSVGESYANAPEIRPPSNGEELFRTRCASCHSLGPMDGQGIGMRSIGPDLVGVTRQRDPAWLNRWIREPDRMLAEKDPIATALFERFDKIPMPNLRLDERSVQSIIEFLQAETDRQQPLLTPLTVGAEEPQHQQAIAAPDKARVQ
>NZ_CP051487.1|WP_168757852.1|2719003_2720497_+|HAMP-domain-containing-histidine-kinase
MQILESPQVPAPVTSATEGKDWRSPFNLVRWFSLASFFIIAGVALGLGYISTRFVVEESIERDSMLTAQFVQAIGAAEIRHASISPNRTMGEMLDPRADAAYPDVDPGARAAARIEFLDHVEHLPDILLATVYALDRTVVWSTNPELIGVRIDNDEELDESFEMKAAVSTSYHEIDEERPEQRLLHEPQYLFVENYIPMFNADKSKVVAMVEVYKEPVDLVERIQRGFRAIWLTTLLGGAVIYLGLFWIVRRAALLLHSQQKQLVANETFVALGEMSSAVAHSLRNPLANIRSSAELAQEIASQTAQKNIGDIISQVDRMSRWVRELLVSLRPVNDDHETVDLVLAIDDTLSAYAPQIQRSNVEVRFTPMTVPPVVSQQVLLTQILNSLFANALEAMPKGGVLSIDVETPASGQVRMILNDTGKGMTKQQQQMVFKPFFTTKQGGLGVGLALVKRIMERFEGSVELTSQEQEGTRVCLNFKVATGGEYGAQHTAGRG
>NZ_CP051487.1|WP_168757853.1|2720465_2721896_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MEHSILLVEDDELLAENIQTYLERKNFEVTVCHSAEDALSQLSTFVPDVVLTDNSLPGMNGHDLIQKLRISAPDLKVIMMTGYGNVEDAVVAMKEGAFHYVTKPVALPELKLLLDKALATDRMERTLSFYQEREAQKSGVQALIGESAPMVYLKGTIAQLLDAERRMANSDLPPVLVEGETGTGKELVARALHFDGPRSKGPFIEFNCASIPSNLVESELFGHEKGAFTDAKDRRLGLVEAADGGTLFLDEIGEMDLILQAKLLKLLEDRTIRRVGSVKERKVDLRVISATNCNLEQMVQQGKFRRDLFFRLRIISIKVPRLYARGEDILLLARHFLASHGKRYGKPHLRFSDQAEELLLNYTWPGNVRELRNMLEQTVLLAQHDTIAAHQLNVCLSLVDEPAMFTHELQPIEPRASHNGTESMNLPEVERDMVRKMLDKTDWNVTKSARLLGLSRDMLRYRIEKLGLARPDKRSW
>NZ_CP051487.1|WP_168757854.1|2721926_2722307_-|hypothetical-protein
MNTTVPTLLLALCLAASCAQADDSAMQTEESSSEFNYYGADQPFAHPVPPTLSTVPPGSYIPTSPQTFTPVSSQHVFSDSRLPTVADTTVRVFIRTYDAEHGVYVNQEVLDPTCMLACRSGQNPAL

Crispr_ID: NZ_CP051487_5

• CRISPR_ID: NZ_CP051487_5
• CRISPR_location: 2783300-2783457
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_5

Consensus_repeat	Method
AACGGATATGTACACCTGAAAGACAATCACCGTCTGCCAGAACGCCTTCGCC	CRISPRCasFinder

spacers of NZ_CP051487_5

>5.1|2783352|54|NZ_CP051487|CRISPRCasFinder
GGCAAGCCTGGCTCCTACAGTAAAAGCGAAAACCTAAGTGGCCGTTACCGCAGC

CRISPR arrays and Neighbor proteins around NZ_CP051487_5

CRISPR arrays

The CRISPR arrays of NZ_CP051487_5

>merge|NZ_CP051487|5|2783300-2783457|CRISPRCasFinder
AACGGATATGTACACCTGAAAGACAATCACCGTCTGCCAGAACGCCTTCGCCGGCAAGCCTGGCTCCTACAGTAAAAGCGAAAACCTAAGTGGCCGTTACCGCAGCAACGGATATGTACACCTGAAAGACAATCACCGTCTGCCAGGACGCCTTCGCC

>NZ_CP051487|5|5|2783300-2783457|CRISPRCasFinder
AACGGATATGTACACCTGAAAGACAATCACCGTCTGCCAGAACGCCTTCGCC	GGCAAGCCTGGCTCCTACAGTAAAAGCGAAAACCTAAGTGGCCGTTACCGCAGC
AACGGATATGTACACCTGAAAGACAATCACCGTCTGCCAGGACGCCTTCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_168757435.1|2783778_2784726_+|IS110-family-transposase	unknown	unknown	gnl|CDD|376564
NZ_CP051487.1|WP_020801339.1|2778841_2779768_-|universal-stress-protein	unknown	unknown	gnl|CDD|236871
NZ_CP051487.1|WP_020801344.1|2774795_2775050_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_020801343.1|2775206_2776421_+|cytochrome-c-biogenesis-protein-DipZ	unknown	unknown	gnl|CDD|239310
NZ_CP051487.1|WP_020801340.1|2777978_2778791_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NZ_CP051487.1|WP_033041414.1|2787006_2787450_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380345
NZ_CP051487.1|WP_116287586.1|2781544_2783094_-|IS3-family-transposase	unknown	unknown	gnl|CDD|366234
NZ_CP051487.1|WP_020801341.1|2777669_2777939_+|DUF4242-domain-containing-protein	unknown	unknown	gnl|CDD|379428
NZ_CP051487.1|WP_168757871.1|2792574_2792853_-|DUF3303-domain-containing-protein	unknown	unknown	gnl|CDD|378707
NZ_CP051487.1|WP_168757870.1|2787635_2790233_+|DNA-ligase-D	unknown	unknown	gnl|CDD|235658
NZ_CP051487.1|WP_020798175.1|2790317_2790992_-|DUF3313-domain-containing-protein	unknown	unknown	gnl|CDD|378712
NZ_CP051487.1|WP_020798292.1|2785175_2785898_-|phosphatidylserine-synthase	unknown	unknown	gnl|CDD|224104
NZ_CP051487.1|WP_020798173.1|2793067_2793469_-|hypothetical-protein	unknown	unknown	gnl|CDD|140294
NZ_CP051487.1|WP_168757869.1|2786146_2786890_+|tellurite-resistance-TerB-family-protein	unknown	unknown	gnl|CDD|377342
NZ_CP051487.1|WP_168757868.1|2784784_2785171_-|DUF488-family-protein	unknown	unknown	gnl|CDD|225730
NZ_CP051487.1|WP_020801342.1|2776506_2777493_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378976
NZ_CP051487.1|WP_151141862.1|2791038_2792307_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|367457
NZ_CP051487.1|WP_008063067.1|2773453_2774194_-|response-regulator	unknown	unknown	gnl|CDD|181883
NZ_CP051487.1|WP_168757867.1|2772146_2773457_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_CP051487.1|WP_033045036.1|2774488_2774752_+|DUF2790-domain-containing-protein	unknown	unknown	gnl|CDD|371321

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_168757435.1|2783778_2784726_+|IS110-family-transposase	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	1.20543e-21
NZ_CP051487.1|WP_020801339.1|2778841_2779768_-|universal-stress-protein	gnl|CDD|236871	PRK11175, PRK11175, universal stress protein UspE; Provisional.	4.23318e-41
NZ_CP051487.1|WP_020801343.1|2775206_2776421_+|cytochrome-c-biogenesis-protein-DipZ	gnl|CDD|239310	cd03012, TlpA_like_DipZ_like, TlpA-like family, DipZ-like subfamily; composed uncharacterized proteins containing a TlpA-like TRX domain. Some members show domain architectures similar to that of E. coli DipZ protein (also known as DsbD). The only eukaryotic members of the TlpA family belong to this subfamily. TlpA is a disulfide reductase known to have a crucial role in the biogenesis of cytochrome aa3.	3.94103e-77
NZ_CP051487.1|WP_020801340.1|2777978_2778791_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.27872e-27
NZ_CP051487.1|WP_033041414.1|2787006_2787450_-|cupin-domain-containing-protein	gnl|CDD|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	3.96442e-20
NZ_CP051487.1|WP_116287586.1|2781544_2783094_-|IS3-family-transposase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.42228e-24
NZ_CP051487.1|WP_020801341.1|2777669_2777939_+|DUF4242-domain-containing-protein	gnl|CDD|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	4.07517e-32
NZ_CP051487.1|WP_168757871.1|2792574_2792853_-|DUF3303-domain-containing-protein	gnl|CDD|378707	pfam11746, DUF3303, Protein of unknown function (DUF3303). Several members are annotated as being LysM domain-like proteins, but these did not match any LysM domains reported in the literature.	2.35529e-24
NZ_CP051487.1|WP_168757870.1|2787635_2790233_+|DNA-ligase-D	gnl|CDD|235658	PRK05972, ligD, ATP-dependent DNA ligase; Reviewed.	0
NZ_CP051487.1|WP_020798175.1|2790317_2790992_-|DUF3313-domain-containing-protein	gnl|CDD|378712	pfam11769, DUF3313, Protein of unknown function (DUF3313). This a bacterial family of proteins which are annotated as putative lipoproteins.	1.30175e-57
NZ_CP051487.1|WP_020798292.1|2785175_2785898_-|phosphatidylserine-synthase	gnl|CDD|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	1.56521e-37
NZ_CP051487.1|WP_020798173.1|2793067_2793469_-|hypothetical-protein	gnl|CDD|140294	PTZ00268, PTZ00268, glycosylphosphatidylinositol-specific phospholipase C; Provisional.	0.000831906
NZ_CP051487.1|WP_168757869.1|2786146_2786890_+|tellurite-resistance-TerB-family-protein	gnl|CDD|377342	pfam04391, DUF533, Protein of unknown function (DUF533). Some family members may be secreted or integral membrane proteins.	1.20625e-52
NZ_CP051487.1|WP_020801342.1|2776506_2777493_-|AraC-family-transcriptional-regulator	gnl|CDD|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	1.32789e-45
NZ_CP051487.1|WP_168757868.1|2784784_2785171_-|DUF488-family-protein	gnl|CDD|225730	COG3189, COG3189, Uncharacterized conserved protein [Function unknown].	1.37914e-35
NZ_CP051487.1|WP_151141862.1|2791038_2792307_-|outer-membrane-beta-barrel-protein	gnl|CDD|367457	pfam03349, Toluene_X, Outer membrane protein transport protein (OMPP1/FadL/TodX). This family includes TodX from Pseudomonas putida F1 and TbuX from Ralstonia pickettii PKO1. These are membrane proteins of uncertain function that are involved in toluene catabolism. Related proteins involved in the degradation of similar aromatic hydrocarbons are also in this family, such as CymD. This family also includes FadL involved in translocation of long-chain fatty acids across the outer membrane. It is also a receptor for the bacteriophage T2.	7.12117e-74
NZ_CP051487.1|WP_008063067.1|2773453_2774194_-|response-regulator	gnl|CDD|181883	PRK09468, ompR, osmolarity response regulator; Provisional.	8.2154e-77
NZ_CP051487.1|WP_168757867.1|2772146_2773457_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.21794e-45
NZ_CP051487.1|WP_033045036.1|2774488_2774752_+|DUF2790-domain-containing-protein	gnl|CDD|371321	pfam10976, DUF2790, Protein of unknown function (DUF2790). This family of proteins with unknown function appear to be restricted to Pseudomonadaceae.	1.48542e-15

Protein sequences

>NZ_CP051487.1|WP_116287586.1|2781544_2783094_-|IS3-family-transposase
MTYYSPERKAALLKMLLPPLSLTVAEVCRREGVSDVSMYLWRKMANQGSKVPDDILLSDKWSAEARFAAVLETASLTQLELGEYCRRNGLYPEQLNAWRQACISGQEAVQAQKMADHEQTRKDKKRILELERELRRKDAALAETAALLVLRKKPQRLLGDRRRGQLTSLPERQLLVGWLIEAIVAGARKIRACQEVGLSLRTLQRWTQPQELQADARTTTLRPKPRNALSEIERHAIVALCNSPTYAHLPPSQIVPRLADEARYLASETTFYRVLRAAGQQHHRGRSRRPRRVVMPTTHAAEKPNQVWSWDITYLPSPIRGKYYYLYLIEDIYSRKAVGWEVYEEESGEKAAALLQRSVISEKCLREPLVLHSDNGAPMKSVTLLSKMYELGITPSRGRPRVSNDNPYSESLFRTLKYCPQWPLEGFASLDAARTWVRDFMRWYNTEHRHSRIRFVTPSERHRGQDHQILVLRHQLYERARQKTPERWSGKTRNWEPIGTVLLNPDRVQQTGKKAA
>NZ_CP051487.1|WP_020801339.1|2778841_2779768_-|universal-stress-protein
MSGQSRFMLVTSPLMEHSPAFDRATALAKAEGAALHIVAFDYLEGLATAGMVNEKALEQMRLGYVDRHRQWLEDQARPLRKIGVTVTTEVTWVQNPLEEILIHLKEQPMDVLIKALEHQSLLSRLIFTPLDVHLLRECPVPLHFVSHAINALPRKVVAAIDPFHRDDHYKTFNDRILHEATKLATACNAELDVVYAYDLSSISSDEFGFDNGSAFFSSTKHKTLYDAQLEAFNELAQRNGIAEAQRHMIMGNPAKVLTRFADAFNVDVIVMGRLGHRGMGRLIGSTVEHLLYKMPCSVWVVYTERLDE
>NZ_CP051487.1|WP_020801340.1|2777978_2778791_+|class-I-SAM-dependent-methyltransferase
MSTPIDLTALKTRQMAAWASGDYAVIGTTLQIVGEQLAEACDLLCDEQVLDVAAGNGNATLAAARRGCRVVSTDYVAALLERGEDRARAERLNVTFQVADAEALPFADASFDAVLSTFGVMFAPDQVKAAAELARVCRPGGRIGLANWTPEGFVGQMFKTLGRHMPPPPGAQPPSQWGTEAWLHKHFDERDFLVQVTRRTFNFRYRSAEHFIDTFRSWYGPIHKAFAALPPDGAKALEDDLTELLNRLNRAGDRSMVVPSEYLEVVITRR
>NZ_CP051487.1|WP_020801341.1|2777669_2777939_+|DUF4242-domain-containing-protein
MPKFVIEREIPGAGALSERDLKAVSQKSCKVLRDLPDLQWLQSYVTGDKLYCVYIAPNEELIREHARQGGFPANRISQVMNIIDPTTAE
>NZ_CP051487.1|WP_020801342.1|2776506_2777493_-|AraC-family-transcriptional-regulator
MDALSQTLRVVRLVGAIFINARFTAPWCYQSPSADTAAPFLEPGAERVVIFHLITEGECYVELGDDPPLLLNPGDVVIFPQGHAHRMSSRPGLTPASGARLDEVLARRPRQLSYGGGGAVTRLVCGYLACDTRLAGMLLAGLPPVVRVNVRGSNAGIWLESSVRYALAEARSPRPGGEGVLAKLAEVLFIEVLRLYMHEHGEGRTGWLAGVSDRIVGAALNALHKKPCHAWTLDELARTAGTSRSVLAERFAQLVGVTPMQYLTQWRMLLAANLLRSSNSSLMRIAEEVGYQTDTAFSRAFRREYGAPPAAWRRSQGNRSMAHGEVSH
>NZ_CP051487.1|WP_020801343.1|2775206_2776421_+|cytochrome-c-biogenesis-protein-DipZ
MLLIAFLGGILTVLSPCILPVVPFLFAGADRTRSSILLTLGGMALTFALISSLAVVSSEWVIQASNTGRHVALIVMVVFALSLISARVGDWLARPFVALGNRIDPNSRTMSGPLSSIMIGVATGLLWAPCAGPILGVILTSAMLQGANAGTSLLLVAYGLGSALSLGTLIFAGRGLVNRLKPSIPVTGWLRRGAGVAVLAGAAVIATGANDVLLANTSSQGISSVEKGLLETVPKVVDYFVSKVKAESMDNAQGAMPSLAGAVEWINSPALTNESLKGKVVLVDFWTFDCINCKHTLPYVKDWAKKYEKDGLVVIGVHTPEYGFERIIDNVRDKVKEYGITYPVAIDNNYAIWRNFDNQYWPAHYLIDAKGQVRYTHFGEGSYDTQEKMIQQLLEEAKTAVPAA
>NZ_CP051487.1|WP_020801344.1|2774795_2775050_+|hypothetical-protein
MNTISRFLTAIAFSVAGAAAHANAAVEQNACGSSTCFQLTPVAQKGADAFLAEDGYNRTPQGQVVAENGASHTSQGKWLEEHNA
>NZ_CP051487.1|WP_033045036.1|2774488_2774752_+|DUF2790-domain-containing-protein
MNTKAIYAACLFAALNICTLSARAEADVTPMSYSYGSHLDIKKVLSLKQDSAPSCGVVNAQLTYLDSQSKTQVLDYRKLADNCNSDN
>NZ_CP051487.1|WP_008063067.1|2773453_2774194_-|response-regulator
MEHVDHILIVDDDREIRELVGNYLKKNGLRTTVVADGRQMRSFLESTPVDLIVLDIMMPGDDGLMLCRELRAGKHKATPVLMLTARNDETDRIIGLEMGADDYLVKPFAARELLARINAVLRRTRMLPPNLVVTESSRLLAFGRWRLDTSARHLLDGDGTMVALSGAEYRLLRVFLDHPQRVLNRDQLLNLTQGRDADLFDRSIDLLVSRLRQRLLDDAREPAYIKTVRSEGYVFSLPVEIVGAPA
>NZ_CP051487.1|WP_168757867.1|2772146_2773457_-|HAMP-domain-containing-protein
MNLSLRWPRTLASRLSLIFLIGLILAQALSFGAQYYERYESSKNTMLGNLETDVSTSIAILDRLPAPERASWLQQLDRRNYRYLLNEGSPGTAMDTDMLEAPIAMTSIKNSIGKDYPMTFSDIPGPAKHFQVHLKLSDGSPLTIDVRPSMVPLSPWLPMVLLGQLALMIACTWLAVRIAIRPLTRLAEAVDTLDPNTHPVLLDEKGPTEVAHAAKAFNAMQARIAAYLKERMQLLAAISHDLQTPITRMKLRAEFMDDSVEKDKLWNDLGEMEHLVREGVAYARSVHGATEESRRTDLDSFLDSLVFDYQDMGKQVQLSGKSAIVIDTRPHALRRVLVNLTDNALKFAGAAELLVEKKADGSVSVKVMDRGPGIAEAELAQVMQPFYRVENSRNRSTGGTGLGLAIAQQLALAIGGSLTLSNREGGGLCAELKLRG
>NZ_CP051487.1|WP_168757435.1|2783778_2784726_+|IS110-family-transposase
MAMPVSVSKPIVGVDVAKKELVIYHAELDLLEEIPNNKTSINKWLKDLPGSVAIAVEATNIYHLEFADLAFEAGCVIYMVGGYELKHYREGVKVRAKTDALDAKLLARYLKNEHEELHPWTPPTPLYRQLLSLFRRRAALVQARVGLVQSWSNEPLLKAAFSEQIKSMQQLETLIEKTINDQLKEAGLLGQLKRCLKVEGVGFLTGARLLTAFQRGDFRNADAFIAFLGMDLRVSKSGQKDGRRSLTKRGDPEARRLLHNAAMSASRTEAWKGFYQEQRNRGFSTTQALVMLARKLARIVFALLKGQSEYQPKTS
>NZ_CP051487.1|WP_168757868.1|2784784_2785171_-|DUF488-family-protein
MPIHIVRLGSARKPDEGLRLGTVRRPPRGVPKAEFASRDFYDVWQPLLSPSPELVQQAQAAEDDKAWNAFRRKFKAEMNHPAPSQLLDLLAALSHNTSLAVGCYCEDEAHCHRSVLRELLEARGAVVV
>NZ_CP051487.1|WP_020798292.1|2785175_2785898_-|phosphatidylserine-synthase
MISTLHIARLKAWGAHGFTATGVVTAFLATLALLDNQPTSCLLWLGVALIVDGLDGALARRVNVQSVLPSFDGSILDLVIDYLTYVFIPALFIYRYIPLPDYTLLLTVSLILVSSLFCFCNVNMKSKDNYFQGFPAAWNVVALCLYIIAPSPWITFLTVIGLALLTLTRMKFLHPFRVRRFMPINIAVTAIWLLCSLSLVINHPVINPMVMGLWLLMSAYFLGICFWRTALEWFDESRLK
>NZ_CP051487.1|WP_168757869.1|2786146_2786890_+|tellurite-resistance-TerB-family-protein
MNTSDLLEQLLRAGQGSMAQRGGGGASAQGGLGDLGGLLGGLLGGGGTSRSGAGGMGGLGGLLGGLLGAGSPMGGAPQSRSAGGTNYAALASLGMMAFQAFQAWQRSQATQQQQAPQQAMRTVDMLAGPEVEEHSHAILRAMIAAAKADGRFDDAETQMINAEIARHTDDPQLQQWLDEEAAKPLDPAEVAQSATDPGIAAEMYLASVMLVDDQQDAERSYLDELAAALGIEPDLQVHLEQQAHGTA
>NZ_CP051487.1|WP_033041414.1|2787006_2787450_-|cupin-domain-containing-protein
MRTVHVLQSPPASVNVVGEKITVLAGGDLSKPFEMHIQEGIQGGGPPPHFHPWDEAFYVVDGQVEVTVEGTSTTVSAGGYVHIPAGSIHAYKNVSPTAKMIGVVSDPRGGLFFTAMDRFKVPEDLPRIFEVAERFGVTFLVPEPPIS
>NZ_CP051487.1|WP_168757870.1|2787635_2790233_+|DNA-ligase-D
MNKNLDDYNRMRDFSATSEPVAVKPKGRKKTKDHALQFCIQKHDASRLHYDFRLELDGALKSWAVPKGPSLDPKVKRLAVHVEDHPLDYATFEGSIPEGHYGAGDVIVWDRGVWIPQDDPAKAYAKGRLKFELQGEKLGGLWNLVRTHMPGKQEQWFLIKHQDGAARPESDYDVVVAEPDSVLSERTLVAKTPKTPKASKATKAKSIKQPASPARKEQSAPLTGARKAELPDQIKPELATLVEKAPGGQWSYEVKFDGYRIMARIDHDEVKLFTRNGHDWTHKLPDQAKALAGLGLESAWLDGEMVVADEQGVPDFQALQNAFEAGRSGNILYYLFDLPYLNGVDLREVPVEERRAALSTVLKTSKDPLLRFSDAFGEDPEALLNSACQMQMEGLIGKRLGSPYVSRRSSDWVKLKCKHRQEFVIVGFTDPKGSRSAFGALLLGLHDRDSGELRYAGKVGTGFTEATLNSIHQQLKPLQTKKAAVVNPPSGAEFKAVHWLKPSLLAEVAFAEMTKDGSVRHAVFHGLRDDKPAKDITEERPTAVKTTPAKKTVAKPTTSKKKVEPAPSQVGLEQGKVRITHPDRVIDASTGATKVQLAQYYASVAEWILPQLKDRPVALVRAPDGIAGELFFQKNAERLAIPGITTLDQQLTGQPMMVINNAEALIGAVQMSTVELHTWNATTDNLDKPDRFVLDLDPDPALPWKRMVEATQLTLTVLDELGLKAFLKTSGGKGIHLVVPLTRKHGWDEVKDFSHAIVSHMAKMLPERFSAVSGPKNRVGRIFIDYLRNGLGATTICAYAVRTREGLPVSMPIFREEVPTLKGGNQWNIHNAHERLAEVGDEPWADLKKTRQTITAEMRRRVGMK
>NZ_CP051487.1|WP_020798175.1|2790317_2790992_-|DUF3313-domain-containing-protein
MNLSRKLLVGTALAGLLLGGCTSKVTEREQYSGYLSNYNNLQEVETPSGGTAMRWVSPSWNPDAYDTVAFNRLELYPAPKPNERVNQQTLNDIQNYMTSKAKSTLGQKYRVVSSPSAAPKGAKTLVMRAAITGVSASNEGMKWYEVVPIAAVVGATQAATGHRDQDTELFIEAEFIDAKSNQTVAKVVRKVFGKQLSNESQKITAQDFKAAIDKLGSDFQAFIK
>NZ_CP051487.1|WP_151141862.1|2791038_2792307_-|outer-membrane-beta-barrel-protein
MQLKNCALPAVSLLALCCQQVQAGGIMLYEVGTDNVGLANAGAAARAQGPSTIASNPAGMSYLPGTQITAGLQVLYGDISFDRDDGTNVSGSGSGNALDPLPGGSFFVSHELDDHWSVGFGQYGDFGLAVNYDNDWSGRYFSQNSSLLGLSLVPSVAYRFNDQWSVGVGVKAMYGMLQAQTAIDRSPFGFTERGDGQFKYKDKDWGFGANVGVIYAPQPGTRIGLTYTSKVDLEFEDGLDIKGNGPLLQRLDGTNTELDITVPQTVTLSLFQQLDRQWALLASINWQDWSEFGDIGVQVDTSANDARSTNIDAGFKDTWHLSLGAQYQATEQWLWNVGVAYDSSAVSDSKRSVIVPMAESWRIATGATYALNKDTDVNLSWAMVWMGDMPVDQSKDLSRNRISGQFDNTWIQAVTGNMTWRF
>NZ_CP051487.1|WP_168757871.1|2792574_2792853_-|DUF3303-domain-containing-protein
MLFIVSWKISSANRNSAIERFLKTGGAPPEGVKMLGRWHAVGGAAGFGVAEANDPVLIQKWVLQWSDLMTMEVQAALTDEQIAPLLATAAGR
>NZ_CP051487.1|WP_020798173.1|2793067_2793469_-|hypothetical-protein
MITSAPIRQPCPPGACDCGRDPLLETPGADVRILFLTRAEEKRLVERLENLQSLQDLEHLQRRMFEQLGIRVNIAPGFNEVRTMRGIGIHIDELPGLCRKTRAAIPAAIRRAMEKRPQIAFELLNANDLLRDT

Crispr_ID: NZ_CP051487_6

• CRISPR_ID: NZ_CP051487_6
• CRISPR_location: 3053738-3053850
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_6

Consensus_repeat	Method
CGCGAAGAACGATGACGCGGTGCAACAGGTACACCGCGGCG	CRISPRCasFinder

spacers of NZ_CP051487_6

>6.1|3053779|31|NZ_CP051487|CRISPRCasFinder
CCCGGTTCGCCGGCAAGCCTGGCTCCTACAG

CRISPR arrays and Neighbor proteins around NZ_CP051487_6

CRISPR arrays

The CRISPR arrays of NZ_CP051487_6

>merge|NZ_CP051487|6|3053738-3053850|CRISPRCasFinder
CGCGAAGAACGATGACGCGGTGCAACAGGTACACCGCGGCGCCCGGTTCGCCGGCAAGCCTGGCTCCTACAGCGCGAAGAACGATGACGCGGTGCAACAGGTACACCGCGGCG

>NZ_CP051487|6|6|3053738-3053850|CRISPRCasFinder
CGCGAAGAACGATGACGCGGTGCAACAGGTACACCGCGGCG	CCCGGTTCGCCGGCAAGCCTGGCTCCTACAG
CGCGAAGAACGATGACGCGGTGCAACAGGTACACCGCGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_168757975.1|3052159_3052831_-|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715
NZ_CP051487.1|WP_020797783.1|3044200_3044866_-|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_CP051487.1|WP_020798534.1|3058537_3060160_-|MHS-family-MFS-transporter	unknown	unknown	gnl|CDD|340927
NZ_CP051487.1|WP_168757974.1|3051112_3052045_-|4-hydroxyproline-epimerase	unknown	unknown	gnl|CDD|172473
NZ_CP051487.1|WP_020798535.1|3058068_3058437_+|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_CP051487.1|WP_033045606.1|3066536_3067592_-|peptidase-M4-family-protein	unknown	unknown	gnl|CDD|341060
NZ_CP051487.1|WP_020797786.1|3047694_3048444_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NZ_CP051487.1|WP_168757977.1|3053940_3055680_-|dipeptidase	unknown	unknown	gnl|CDD|235720
NZ_CP051487.1|WP_168757971.1|3044858_3046637_-|DUF521-domain-containing-protein	unknown	unknown	gnl|CDD|377349
NZ_CP051487.1|WP_168757979.1|3063153_3064245_-|DNA-alkylation-repair-protein	unknown	unknown	gnl|CDD|226785
NZ_CP051487.1|WP_020798530.1|3064302_3066111_-|transporter-monovalent-cation:proton-antiporter-2-(CPA2)-family	unknown	unknown	gnl|CDD|235131
NZ_CP051487.1|WP_083348934.1|3053141_3053600_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_CP051487.1|WP_168757980.1|3066216_3066540_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_168757973.1|3050000_3051116_-|FAD-binding-oxidoreductase	unknown	unknown	gnl|CDD|223737
NZ_CP051487.1|WP_168757972.1|3048518_3049775_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223523
NZ_CP051487.1|WP_020798532.1|3062143_3063046_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP051487.1|WP_168757978.1|3060376_3062023_-|choline-dehydrogenase	unknown	unknown	gnl|CDD|235000
NZ_CP051487.1|WP_033043154.1|3046647_3047466_-|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|270414
NZ_CP051487.1|WP_083350152.1|3055868_3057812_-|DNA-topoisomerase-III	unknown	unknown	gnl|CDD|236078
NZ_CP051487.1|WP_083348931.1|3049771_3050008_-|(2Fe-2S)-binding-protein	unknown	unknown	gnl|CDD|379229

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_168757975.1|3052159_3052831_-|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.69294e-53
NZ_CP051487.1|WP_020797783.1|3044200_3044866_-|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99995e-60
NZ_CP051487.1|WP_020798534.1|3058537_3060160_-|MHS-family-MFS-transporter	gnl|CDD|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.74861e-123
NZ_CP051487.1|WP_168757974.1|3051112_3052045_-|4-hydroxyproline-epimerase	gnl|CDD|172473	PRK13970, PRK13970, 4-hydroxyproline epimerase.	9.2299e-168
NZ_CP051487.1|WP_020798535.1|3058068_3058437_+|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	2.33187e-40
NZ_CP051487.1|WP_033045606.1|3066536_3067592_-|peptidase-M4-family-protein	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	1.45747e-125
NZ_CP051487.1|WP_020797786.1|3047694_3048444_-|AraC-family-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.42328e-27
NZ_CP051487.1|WP_168757977.1|3053940_3055680_-|dipeptidase	gnl|CDD|235720	PRK06156, PRK06156, dipeptidase.	0
NZ_CP051487.1|WP_168757971.1|3044858_3046637_-|DUF521-domain-containing-protein	gnl|CDD|377349	pfam04412, DUF521, Protein of unknown function (DUF521). Family of hypothetical proteins.	0
NZ_CP051487.1|WP_168757979.1|3063153_3064245_-|DNA-alkylation-repair-protein	gnl|CDD|226785	COG4335, COG4335, DNA alkylation repair enzyme [DNA replication, recombination, and repair].	4.69904e-57
NZ_CP051487.1|WP_020798530.1|3064302_3066111_-|transporter-monovalent-cation:proton-antiporter-2-(CPA2)-family	gnl|CDD|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
NZ_CP051487.1|WP_083348934.1|3053141_3053600_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.00735e-09
NZ_CP051487.1|WP_168757973.1|3050000_3051116_-|FAD-binding-oxidoreductase	gnl|CDD|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	3.97966e-48
NZ_CP051487.1|WP_168757972.1|3048518_3049775_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	1.03711e-32
NZ_CP051487.1|WP_020798532.1|3062143_3063046_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	6.66298e-36
NZ_CP051487.1|WP_168757978.1|3060376_3062023_-|choline-dehydrogenase	gnl|CDD|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_CP051487.1|WP_033043154.1|3046647_3047466_-|transporter-substrate-binding-domain-containing-protein	gnl|CDD|270414	cd13696, PBP2_Atu4678_like, The substrate binding domain of putative amino acid transporter; the type 2 periplasmic binding protein fold. This group includes the periplamic-binding protein component of a putative amino acid ABC transporter from Agrobacterium tumefaciens and its related proteins. The putative Atu4678-like domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.84764e-112
NZ_CP051487.1|WP_083350152.1|3055868_3057812_-|DNA-topoisomerase-III	gnl|CDD|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP051487.1|WP_083348931.1|3049771_3050008_-|(2Fe-2S)-binding-protein	gnl|CDD|379229	pfam13510, Fer2_4, 2Fe-2S iron-sulfur cluster binding domain. The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which a beta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated. This cluster appears within sarcosine oxidase proteins.	8.91778e-18

Protein sequences

>NZ_CP051487.1|WP_083348934.1|3053141_3053600_-|transposase
MPTIHQAHRLRTGRFSAPGQIYLVTTVVQNRDPVFRDFMQGRLVVDALKKAQEEELVLSLAWVVMPDHLHWLFELKNNTLTCIMARTKSRITLALNRSLERDGSLWQHGFHDRAIRRDEDLPAVARYIVANPLRAGLVEKIGDYPLWDAVWL
>NZ_CP051487.1|WP_168757975.1|3052159_3052831_-|GntR-family-transcriptional-regulator
MNSPKFNAPDLGNAPSTSEIITRHLRDAIVAGHFAEDEPIRQDDIARQFNVSKIPVREALKRLEAEGLVMFQRNRGAMVTRVSDAELAQMFEVRMLLEDKVLRLAIPNMTEDTFARAERICQEFIGEDDVGRWAELNWELHACLYEPAQRPFLVSLIRSVNDKLERYLRMQMSLSSGKERADHEHREIVEACRVGDVDRAVKLLDEHIAGVCKTLFEHLPHHP
>NZ_CP051487.1|WP_168757974.1|3051112_3052045_-|4-hydroxyproline-epimerase
MKRITVIDSHTGGEPTRLVTGGFPDLGTGSMAERLRRLAEHHDQWRAACVLEPRGSDVLVGALLCEPVDPAACAGVIFFNNTGYLGMCGHGTIGLVASLAHLGKIGPGVHSIETPVGTVQATLHDDYSVSVRNVPAYRYRKAVALQVPGIGQVVGDIAWGGNWFFLIAEHGLRIDSDNLETLTAYTYAVQQALDIQGIRSEDGGLIDHVELFADDAQADSRNFVLCPGKAYDRSPCGTGTSAKLACLAADGKLQPGQIWRQASVIGSEFEGSYERHGERIVPTIRGRAFISAEASLIIEQADPFAWGIRP
>NZ_CP051487.1|WP_168757973.1|3050000_3051116_-|FAD-binding-oxidoreductase
MNQGLVADVIVIGAGIIGAACAQTLARRGLRVLVLDAGLHGATAAGMGHLLVLDDNPAELALSQYSVQRWREQAPQLPESCSYRSNGTLWLAANAEEMAVAQSKHMNLQARGVTCELITGNALHAREPELRDGLEGGLLINGDGILYAPATANWMLDTPGIEQRRARVSEVDGNRVRLDDGQWLNAEAVILANGIQANDLCPELPIEPKKGHLLITDRYPGKVTHTLVELGYVTSAHNATGPSTACNIQPRPTGQLFIGASRQFGTTDPQVEGWMLAKMLKRATEYMPGLAQLNGIRAWTGFRAASPDGLPLIGQHPKRKGLWLAVGHEGLGVTTAPGTADLLVAQLFNETPPLAVQPYLPQRFLEEAAYA
>NZ_CP051487.1|WP_083348931.1|3049771_3050008_-|(2Fe-2S)-binding-protein
MLDLIMDGRALKVAAGTTVAAALALAGDGCSRTAVSGQRRAPLCGMGICQECRVTIDGRRRLACQTLCQQGMQVQTRA
>NZ_CP051487.1|WP_168757972.1|3048518_3049775_-|NAD(P)/FAD-dependent-oxidoreductase
MNEYADLLIIGAGPAGMSAALAAASSGARIVVLDDNPLPGGQIWRDGPQASLPNQARQMRERLQANSNIRHHAGTRVIALAGAKQLLVEDADRGWLIGYDKLILCTGARELLLPFPGWTLPGVTGAGGLQALIKGGLPVQDERVVIAGSGPLLLASAATAKHNGAQVLRIAEQASAVAVAGFALQLPRWPGKLVQSFSLFDRHYRTGSHVVAALGNDRLEAVRLRHRGKIVELACDRLACGFGLIPNTQLGQALGCALDGSALAVDAWQTTSHTDHYAAGECTGFGGSELALVEGAIAGHVAVGNTAAARDLWPRRARWQGFAKALNSAFSLDPQLKSLAQPDTLVCRCEDVPYSALSGHVGWREAKLASRCGMGACQGRVCGGALQYLFDWQPTAPRPPFNPARIETLMCLDDTPPV
>NZ_CP051487.1|WP_020797786.1|3047694_3048444_-|AraC-family-transcriptional-regulator
MFPSLNHFKPCDLPTLLNSLQAIATLLDTLTDVVFFIKDCEARYVFVNQTLVRRCSFKHSDQLLGLTADRVFPERFGPIYTEQDRRVLATGRELADQLELHLYFGNQPVWCLTHKLALRDEHGQIVGLAGISRDLQLPQSNHPAFQKLAAVDAHIRRHFARPISLAELTAIAGFSVAQLERHCKRVFQLTPRQMIHKSRLEEGTRLLLESDLPITEIALRCGYTDHSAFSRQFRALTSLSPSQFRDRGR
>NZ_CP051487.1|WP_033043154.1|3046647_3047466_-|transporter-substrate-binding-domain-containing-protein
MKTPAFAVALSAVLSTTFIATAQADKLDDIIGSGKLRCAVTLDFPPMGFRDASNAPAGFDVDYCTDLAKVLGVEAEVVETPFPDRIPALISGRADVIVASTSDTLERAKTVGLTVPYFAFQMVVLTRDNTGINSFDDIKGKALGNTSGTYEAIALENDVKKWGTGTFRAYQSQNDTLLAVAQGHIDATVVTNTVAAATIKSGKYKNLKIAGNAPYTIDYVSLGTKRNEYGLLNYLNLFVNQQVRNGRYKELFTKWVGTEISPSDLTVPKVYY
>NZ_CP051487.1|WP_168757971.1|3044858_3046637_-|DUF521-domain-containing-protein
MPRPTSLTVRSLVPGAAQGALLFADVGLSFWGGVDPLRGEIIDRHHPLSGEYLTGRVLAIPSGRGSCTGSSVLMELISNGHAPAALVLAEADEILTLGVLVAQMIFERSLPVLCIGSEAFAALRGKAFARIDGASLAVFDRIPVDNWQPSETPIQIRDTSTAIELSEFDHALLDGAHGKAAQMAMQIVLRLAELQGAQRLIDVTQAHIDGCIYTGPASLRFAQQLVQWGAKVRIPTTLNSISVDQRRWRELGIDPLLGEPASAVGDAYMAMGAQLSFTCAPYLLDSAPKAGDQIVWAESNAVVYANSVLGARTLKYPDYLDICIALTGRAPLIGCHLDAPRKARLRVELPKLAELDDAFYPLLGYHIGALAGSRIPLIFGLEQRQPDLDDLKAFGAAFATTSAAPLFHIAGVTPEALDPAQVLEPDTPLPVATIRLEDLLVSWRELNSARDNRVDVVSLGNPHFSLSEFARLAQLCRDRVKHPEVVLAITCGRAVLEQARDAGYIDVIETFGATLVTDTCWCMLGEPVIPRAATTLMTNSGKYAHYAPGLVGRNVHFASLAECVDAACTATASGRLPSWLQPALPMENRSHV
>NZ_CP051487.1|WP_020797783.1|3044200_3044866_-|amino-acid-ABC-transporter-permease
MFDYTFQWRTALRALPDMLTGAWVTFETAALSMIFGVLIALVLTVMREARHPLLRGIGNGWVSIARNTPSLFQIYILYFGLGSLGLHVSSWLALLAGITFNNAGYLAENFRGGLKAVPHTQVRAARSLGMSAFQTYRMIIVPQLLRIVFYPLTNQMVWAVLMTSLGVIVGLNNDLTGVTQEYNVKTFRTFEYFAIAAVLYYLIAKAIVAAARLMAWRLFRY
>NZ_CP051487.1|WP_168757977.1|3053940_3055680_-|dipeptidase
MDFSLKHLAAATLVVASLSSFTNAAQANITPQQNAIILKTFSDTSVKDFRQFLKSLAKRDIAKTDDLGTAISAFLDNKTLSPEQQNQIYRLLGLYTRVKYGSAATQTLRELVAIPTVRVDGVAQHDNPEFIKIAEKIKGLAQGFNLSFRNIDNRVYEISLEGAGDEVVGIHAHADVVPVTPENWVLQDGTRLDPFKVTLVGDRMYGRGTEDDKNGIVVTLYAMKVIKEEKLPLARNFKLLVDTTEETTGDAIPYYFERNPTPNYNLALDGGYPVVIAEKGYGTVMASFAKRKAQGKGAEITAMTGGLATNQIPSTSVATLVADNPAELAASLQKAGTEYAMRNGGNFDVAAKVVGNDVMLTVTGVSAHSSEPESGINPVARMLDFINSLDGKVALKHNHITDAARYAADNWGLDYLGGKLAVGFADEFMGPLTTSLTYVGMDDKTFKLAVNLRVPKGKFPQVLKSEIATKLDAWSKNSNIIPAFDFSIAEPMYRNPEGEWVKALLAVASENLGMEHKFGTSAGATSVHELPNGVQFGLAMPDVKYTGHNDNEFKTTEQFLLDLQIVTEMMSRIGQLPKL
>NZ_CP051487.1|WP_083350152.1|3055868_3057812_-|DNA-topoisomerase-III
MRLYLCEKPSQAKDIAAVLGARRRGDGCWLGTDVTVTWCIGHLLETAPPDAYDARYKRWVLADLPIIPDQWKMTVKPRTASQYKVVKRLLGEARELVIATDADREGEMIARELVEHCRYRGPIQRLWLSALDDASIRKALAALKPGAQTFSLYHSALGRSRADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIAAFVPVPYWAVEVQLLHDGTAFTAQWRAASEVCDDQDRCLNQALAQRAAAAMLAAASARVIKLRTERMREVAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETHKVITYPRSDCGYLPLSQHSEAPGILAALRQADPALNALHDYLEPQRRSRAWNDAKVSAHHGIIPTAAAKNLERLAGKQRAVYTLIRARYLAQFLPNHEFDRTQADFDCAGEALRAVGKQIVEPGWKRALPEALAPAKGREAPAPQTLPNLREGIDCAVADVQLKDLWTQPPKPFTEGDLIKAMKNVAKLVEDPLLKQKLKDTTGIGTEATRASIIQGLLDRGYLIKNGKALAATPAAFSLIDAVPRAIADPGTTAIWEQALDMVQSGEMSLDEFVTKQAAWMSKQVSRCAGLSLTISGPASPAGRGATPWKNKRKPAKRKPAGTSKRGTKTAL
>NZ_CP051487.1|WP_020798535.1|3058068_3058437_+|DUF427-domain-containing-protein
MKSSGPSPVITIAEQPGCLLVKFHGIQVAASSRALVLLEANYPPVYYVPREDIDEKYFARTDHTSYCPYKGDASYFSLQVPGHEGANAVWSYENPKVSVAQIREYMAFYPDQVKFELVELDE
>NZ_CP051487.1|WP_020798534.1|3058537_3060160_-|MHS-family-MFS-transporter
MSEHVQPLEAVRSAGTSQETQKVIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTTAFIFALMAFAAGFIVRPFGALVFGRLGDMIGRKYTFLATIVLMGLATFCVGLLPNYASIGIAAPIILVVLRMLQGLALGGEYGGAATYVAEHAPMGKRGFHTSWIQSTATLGLLLSLLVVLGCRYFTGDQFEVWGWRIPFLFSIILLGISTWIRLSLHESPAFVKMKEEGKLCKSPIRDSFGKWENLKVVLIALFSINAGQAVTFYAAQFYVLFFLTQFLKMDPAVANGLLIVSVTIGAPFFIFFGWLSDKVGRKPVLMLGLLLATVLYFPIFKTLAHYANPAIDQASRQAPITVLADPATCTFQFDPVGKAKFDSPCDKVKTFLVKQGLPYQSAAAPAGSDVQVSVGDMKIDGFDEAALRGAVTLAGYPQQADMQQINKPMIVALIVALIIISAMCYGPLAALMVELFPTRIRYTSMSLPYHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVLITGVSLVVGMLCLRETRNVDLDKN
>NZ_CP051487.1|WP_168757978.1|3060376_3062023_-|choline-dehydrogenase
MHASLDEYDYIVVGAGPAGCLLANRLSTNPQHRVLLLEAGGRDNYAWIHIPVGYLFCIGNPRTDWCFKTEAQPGLQGRTLSYPRGKVLGGCSSINGMIYMRGQAGDYDGWAADGNPGWRWQDVLPLFKKSENHFAGESTFHGGSGDWRVERQRLSWLILDAFRSAAEQSGIASIDDFNQGDNEGCGYFQVNQKAGIRWNAAKAFLKPIRQRPNLTVLTGVEVDRVMLENARASAVSARWQGQAKTFKARKEIVLCAGSVGSPSILQRSGIGPRPLLQRLGIGVVHELSGVGGNLQDHLQLRLIYKLENARTLNQIAGSLWGKMGMGLRYLYDRSGPLSMAPSQLGAFARSGPEQTSANLEYHVQPLSLERFGEPLHAFPAFTASVCDLRPQSRGTVQIRSADPQQAPLIQPNYLSHPEDLRVAADAIRLTRRIVAAPALRAFKPVEYLPGDSLQSEEQLHEAAARIGTTIFHPVGTCRMGNDADAVVDAELRVHGIPGLRIADASIMPRITSGNTCSPTLMIAEKAAQLILNPDTRSLTPEKELATHP
>NZ_CP051487.1|WP_020798532.1|3062143_3063046_+|LysR-family-transcriptional-regulator
MFDWNDLRFFLELQRSGRLLTAARRLNTTHATVARHIEAVEKSLGTALFVQHAQGYELTPAGEALLKHAEAMENVALLAQEEITQSTAPLGKIRVGVTEGLGIMFLASRMNGLFERYPGLEVELVAVPRFVSILNREAEISIHLERPAADMLVTRKLADYRLALYASQDYLDRSPALRNREDLGRHAWIGYVDDLLFSQELMFLNSFCRNPQVVFHSTSVIAQQQAARAGLGIAVLPCYMASADPGLVPLLPQESILRSYWISTRRELHKSVRLRVMWDYVVELCEREQELLLGPNPPVI
>NZ_CP051487.1|WP_168757979.1|3063153_3064245_-|DNA-alkylation-repair-protein
MAGDTALKEIFNAERLRHIAAEMTAVYPDFDAKGFLKLANHGLAELSVMRRLARVSECLHAVLPLGYEASLEVLRALAPRLNSSFVSMCLPHYVATYGAERFELSMEALKYFTAFGSSEFAIRHFLRDDLQRSLQLMHDWSLDANEHVRRLASEGCRPRLPWSFRLEPVQADPRLAAGILDNLKADPSLYVRKSVANHLNDITKDQPEWVLDLIEGWSLDNPHTAWIARHALRSLIKQGNLRALAIIGAGGKPEVQIIDVQVNPPVIGLGEKITLSFAVKSTVHNSQRLVIDYAIDYVKANGSTSAKVFKLKALTLPGNATQPITRGQHIKELTTRRHYAGKHAVHVLVNGERLASTAFEILA
>NZ_CP051487.1|WP_020798530.1|3064302_3066111_-|transporter-monovalent-cation:proton-antiporter-2-(CPA2)-family
MPHEGSLLQAAVVFLLAAVLTVPLAKRLQLGAVLGYLFAGVIIGPSGLGLIGNTESVAHISELGVVLLLFIIGLELSPRRLWVMRKAVFGVGLAQVLLTGALLGVLALYVFGQPLNTSIVLGLGLALSSTAFGLQSLAERKELTSPHGRLAFAILLFQDIAAIPLIAMVPLLAGSSANVSAVDDVNQGLRVLVSIAIVVIGGRYLLRPVFRVVAKTGLPEVSTATALLVVMGTAWLMDLAGISMALGAFLAGLLLADSEYRHELEAQIEPFKGLLLGLFFMSVGMGANLGLLLREPIVVLGLTLLLIAVKLPLLFVVGRLAGGLNKISAIRLGIVLAAGGEFAFVVFKIGRDHGLFDPRLYDLLVLAITLSMALTPLLMLLCARLVSPKVQPVVVPEQFRAIDADEPRVVIAGMGRMGQIVARILRAQNIKFVALDTSVETIELSRSFGGVPVYYGDPMRPEILSAAKVADAEFFVIATDDPDTNIKTAELVHKLYPHIKIIARARNRQHVHRLVDLGAHAVRETFYSSLEMSRQTLIGLGLTPEQADARIKRFKHHDEQVLEAQHAIYDDAVKVKQTAQEARAELARLFESDQLEEQAKNG
>NZ_CP051487.1|WP_168757980.1|3066216_3066540_-|hypothetical-protein
MKTLPTLDDRAVVRLSRQGGFAAIQALTRPREIEFAQCDLEQRSRIRGLLEGCLPLASSASGGGDQRFYQIELHYRAGEQDDQMVLKVPENQAPAELVRLWDLGELL
>NZ_CP051487.1|WP_033045606.1|3066536_3067592_-|peptidase-M4-family-protein
MTDLRSFIPPYILHRIVAHGSEHQRSSAMSTLAHVRTLRHTPGPPVRPAAAAILPATSKRGQVQRSVHDAQGKMLLPGMPVRLEGQAPSGDPAVDEAYDALGASYDFFWKVLGRDSIDDKGFALIGSVHYGQDYENAFWNGSQMVFGDGDGEIFQRFTRSLDVVGHELTHGVVESEAGLVYADQSGAMNESLSDVFGVLTKQYLLGHTADQADWLIGADLLTPRIKGVGLRSMAHPGTAYDDPLLGKDPQPDHMRKFVITQEDNGGVHINSGIPNRAFYLAAKALGGFAWETAGLIWYDALCDKRLSHETSFSAFAKLTVEHARRRFSANEARVVQRGWSQVGVETTQEAP

Crispr_ID: NZ_CP051487_7

• CRISPR_ID: NZ_CP051487_7
• CRISPR_location: 3551241-3551311
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DinG

Consensus repeat of NZ_CP051487_7

Consensus_repeat	Method
TTCCTGCGGTAACGGCCGCTTAT	CRISPRCasFinder

spacers of NZ_CP051487_7

>7.1|3551264|25|NZ_CP051487|CRISPRCasFinder
CTTTTGTTGACTGCGTACATATCCA

CRISPR arrays and Neighbor proteins around NZ_CP051487_7

CRISPR arrays

The CRISPR arrays of NZ_CP051487_7

>merge|NZ_CP051487|7|3551241-3551311|CRISPRCasFinder
TTCCTGCGGTAACGGCCGCTTATCTTTTGTTGACTGCGTACATATCCATTCCTGCGGTAACGGCCGCTTAT

>NZ_CP051487|7|7|3551241-3551311|CRISPRCasFinder
TTCCTGCGGTAACGGCCGCTTAT	CTTTTGTTGACTGCGTACATATCCA
TTCCTGCGGTAACGGCCGCTTAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_168758182.1|3550084_3551101_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378890
NZ_CP051487.1|WP_168758185.1|3558435_3560748_-|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|224120
NZ_CP051487.1|WP_033042293.1|3541719_3542826_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|379770
NZ_CP051487.1|WP_020800542.1|3544086_3544860_-|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|180295
NZ_CP051487.1|WP_168758180.1|3540864_3541572_+|HPP-family-protein	unknown	unknown	gnl|CDD|225979
NZ_CP051487.1|WP_020800112.1|3555896_3556373_+|hemerythrin-domain-containing-protein	unknown	unknown	gnl|CDD|376622
NZ_CP051487.1|WP_168758186.1|3560744_3562412_-|VRR-NUC-domain-containing-protein	unknown	unknown	gnl|CDD|370112
NZ_CP051487.1|WP_033044554.1|3553359_3554217_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187613
NZ_CP051487.1|WP_020800546.1|3547395_3548157_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187629
NZ_CP051487.1|WP_020800116.1|3562608_3562833_+|YgdI/YgdR-family-lipoprotein	unknown	unknown	gnl|CDD|380215
NZ_CP051487.1|WP_168758181.1|3548173_3549838_-|AMP-binding-protein	unknown	unknown	gnl|CDD|341277
NZ_CP051487.1|WP_168758183.1|3554343_3555693_+|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104
NZ_CP051487.1|WP_155943756.1|3540722_3540866_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_083349144.1|3546189_3547383_-|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl|CDD|180775
NZ_CP051487.1|WP_168758187.1|3562930_3563590_+|hypothetical-protein	unknown	unknown	gnl|CDD|378282
NZ_CP051487.1|WP_020800544.1|3544928_3546056_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP051487.1|WP_168758184.1|3556520_3558428_-|PAS-domain-S-box-protein	unknown	unknown	gnl|CDD|237425
NZ_CP051487.1|WP_168758188.1|3563616_3565023_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274522
NZ_CP051487.1|WP_033042308.1|3542829_3543981_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
NZ_CP051487.1|WP_168758189.1|3565073_3565889_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|225117

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP051487.1|WP_168758185.1|3558435_3560748_-|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	3.4e-87	287.9	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_168758182.1|3550084_3551101_-|AraC-family-transcriptional-regulator	gnl|CDD|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	4.58017e-37
NZ_CP051487.1|WP_168758185.1|3558435_3560748_-|ATP-dependent-DNA-helicase	gnl|CDD|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	7.70731e-71
NZ_CP051487.1|WP_168758188.1|3563616_3565023_-|FAD-dependent-oxidoreductase	gnl|CDD|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	1.29671e-64
NZ_CP051487.1|WP_020800542.1|3544086_3544860_-|enoyl-CoA-hydratase	gnl|CDD|180295	PRK05862, PRK05862, enoyl-CoA hydratase; Provisional.	3.23072e-156
NZ_CP051487.1|WP_168758180.1|3540864_3541572_+|HPP-family-protein	gnl|CDD|225979	COG3448, COG3448, CBS-domain-containing membrane protein [Signal transduction mechanisms].	1.93801e-50
NZ_CP051487.1|WP_020800112.1|3555896_3556373_+|hemerythrin-domain-containing-protein	gnl|CDD|376622	pfam01814, Hemerythrin, Hemerythrin HHE cation binding domain. Iteration of the HHE family found it to be related to Hemerythrin. It also demonstrated that what has been described as a single domain in fact consists of two cation binding domains. Members of this family occur all across nature and are involved in a variety of processes. For instance, in Nereis diversicolor hemerythrin binds Cadmium so as to protect the organism from toxicity. However Hemerythrin is classically described as Oxygen-binding through two attached Fe2+ ions. And the bacterial NorA is a regulator of response to NO, which suggests yet another set-up for its metal ligands. In Staphylococcus aureus the iron-sulfur cluster repair protein ScdA has been noted to be important when the organism switches to living in environments with low oxygen concentrations; perhaps this protein acts as an oxygen store or scavenger.	5.72814e-09
NZ_CP051487.1|WP_168758186.1|3560744_3562412_-|VRR-NUC-domain-containing-protein	gnl|CDD|370112	pfam08774, VRR_NUC, VRR-NUC domain.	1.31701e-36
NZ_CP051487.1|WP_033044554.1|3553359_3554217_+|SDR-family-oxidoreductase	gnl|CDD|187613	cd05355, SDR_c1, classical (c) SDR, subgroup 1. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.87092e-155
NZ_CP051487.1|WP_168758183.1|3554343_3555693_+|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	1.34534e-42
NZ_CP051487.1|WP_020800116.1|3562608_3562833_+|YgdI/YgdR-family-lipoprotein	gnl|CDD|380215	NF033216, lipo_YgdI_YgdR, YgdI/YgdR family lipoprotein. Members of this family are exclusively lipoproteins of small size, including YgdI and YgdR from E. coli K-12.	4.45504e-26
NZ_CP051487.1|WP_168758181.1|3548173_3549838_-|AMP-binding-protein	gnl|CDD|341277	cd05973, MACS_like_2, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	0
NZ_CP051487.1|WP_020800546.1|3547395_3548157_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187629	cd05371, HSD10-like_SDR_c, 17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs. HSD10, also known as amyloid-peptide-binding alcohol dehydrogenase (ABAD), was previously identified as a L-3-hydroxyacyl-CoA dehydrogenase, HADH2. In fatty acid metabolism, HADH2 catalyzes the third step of beta-oxidation, the conversion of a hydroxyl to a keto group in the NAD-dependent oxidation of L-3-hydroxyacyl CoA. In addition to alcohol dehydrogenase and HADH2 activites, HSD10 has steroid dehydrogenase activity. Although the mechanism is unclear, HSD10 is implicated in the formation of amyloid beta-petide in the brain (which is linked to the development of Alzheimer's disease). Although HSD10 is normally concentrated in the mitochondria, in the presence of amyloid beta-peptide it translocates into the plasma membrane, where it's action may generate cytotoxic aldehydes and may lower estrogen levels through its use of 17-beta-estradiol as a substrate. HSD10 is a member of the SRD family, but differs from other SDRs by the presence of two insertions of unknown function. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.55899e-123
NZ_CP051487.1|WP_033042293.1|3541719_3542826_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|379770	pfam16113, ECH_2, Enoyl-CoA hydratase/isomerase. This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.	4.84865e-170
NZ_CP051487.1|WP_083349144.1|3546189_3547383_-|acetyl-CoA-C-acyltransferase	gnl|CDD|180775	PRK06954, PRK06954, acetyl-CoA C-acetyltransferase.	0
NZ_CP051487.1|WP_168758187.1|3562930_3563590_+|hypothetical-protein	gnl|CDD|378282	pfam09864, MliC, Membrane-bound lysozyme-inhibitor of c-type lysozyme. Lysozymes are ancient and important components of the innate immune system of animals that hydrolyze peptidoglycan, the major bacterial cell wall polymer. Various mechanisms have evolved by which bacteria can evade this bactericidal enzyme, one being the production of lysozyme inhibitors. MliC (membrane bound lysozyme inhibitor of c-type lysozyme) of E. coli and Pseudomonas aeruginosa, possess lysozyme inhibitory activity and confer increased lysozyme tolerance upon expression in E. coli. Structural analyses show that the invariant loop of MliC plays a crucial role in the inhibition of the lysozyme by its insertion into the active site cleft of the lysozyme, where the loop forms hydrogen and ionic bonds with the catalytic residues.	3.0779e-11
NZ_CP051487.1|WP_020800544.1|3544928_3546056_-|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NZ_CP051487.1|WP_168758184.1|3556520_3558428_-|PAS-domain-S-box-protein	gnl|CDD|237425	PRK13557, PRK13557, histidine kinase; Provisional.	3.17482e-106
NZ_CP051487.1|WP_033042308.1|3542829_3543981_+|acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NZ_CP051487.1|WP_168758189.1|3565073_3565889_-|helix-turn-helix-domain-containing-protein	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.16323e-15

Protein sequences

>NZ_CP051487.1|WP_168758182.1|3550084_3551101_-|AraC-family-transcriptional-regulator
MSEKDTISIQLVREALLQSCEPGAATDEVLHKVGIDPALLASSDARVAASAYARLWRLLARRGDDEFFGMDPRKLKSGSLEFLCRCAMVQPSLAAGLTTGLSFLSLMLERMPAELVHQQSLAEIVLLEDGHEPRRAFTYFTYWMIVHGVACWLAGRRIPILAIELRCAQPDFCHDYQVMFSENLRFDRPRTRMIFSADCLGLPIKRSLEELRRFLAHAPANILVKYRDPQSLASRIKQDLRHLPAEQWPETEVLAQSLCMSASTLRRRLAEEGQTYQGLKDSVRKELAIAWLAEPAISFADIAARLGFADTSSFYKAFRKWSGSNPGHYRSLILNESP
>NZ_CP051487.1|WP_168758181.1|3548173_3549838_-|AMP-binding-protein
MRDYLSAVSQFNYQHTVDAALAGNLTALNACIECCDRHALPGRIALFWEGRDGTSATYTFTDLQDKAARFANFLLAQGVKKGDKVAGLLPRNIELLITVFATWRIGAVYQPLFTAFGPKAIEHRLGSSGAKVVVTDAVNRSKLAEVADCPTIVTVAGAKGQGIVRGDYSFWAELANYGNDCEPVLLTGEDPFLLMFTSGTTGPSKALSVPLKAIAAFKGYTLDAVDLRPEDAFWNLADPGWAYGIYFGVTGPLSMGHPITFYDGPFTLESTCRVINKYGITNLTGSPTAYRLLIAGGEEFARSIKGKLRIVSSAGEPLNPEVIRWFADNLDVVIHDHYGQTELGMVLCNHHGLEHPIHMGAAGFASPGHRIVVLDDDYRELGVGQPGILAIDRTQSPMCWFAGYEGAPTKAFVGNYYLSGDTVEWNPDGSISFVGRSDDVITTSGYRVGPFDVESALIEHPAVVEAAVVGKPDPERTELVKAFVVICSQYRATPELAEELRQYVRKRLAAHSYPREIEFVSELPKTPSGKLQRFILRNQEVAKAQEAAAKNVPA
>NZ_CP051487.1|WP_020800546.1|3547395_3548157_-|SDR-family-NAD(P)-dependent-oxidoreductase
MQIENKVFLVTGGASGLGAATAEMLVAAGAKVMLVDMNAEAVAAQAQRLGAQSVVADISSEAAAEAAVQATVKAFGGLNGLVNCAGIVRGEKILGKNGPHALASFSQVINVNLIGSFNMLRLASAAIAETEADADGERGVIINTASAAAYDGQIGQAAYSASKGAIVSLTLPAARELARFGIRVMTIAPGIFETPMMAGMTQEVRDSLAAGVPFPPRLGKPAEYASLVRHIIENSMLNGEVIRLDGALRMAAK
>NZ_CP051487.1|WP_083349144.1|3546189_3547383_-|acetyl-CoA-C-acyltransferase
MTIANDPIVIVSAVRTPMGGFQGELKSLTAPQLGAAAIKAAVERAGVASDAVDEVLFGCVLPAGQGQAPARQAALGAGLDKSTRCTTLNKMCGSGMEAAILAHDMLVAGSAEVVVAGGMESMSNAPYLLDRARSGYRMGHGRVLDSMFLDGLEDAYDKGRLMGTFAEDCAETNGFSREAQDAFAVASTTRAQQAIKDGSFKDEIVPLTVTVGKEQVTISNDEQPPKARLDKIASLKPAFRDGGTVTAANSSSISDGAAALVLMRRSEAGKRGLKPLAVIHGHAAFADTPSLFPVAPVGAIEKLMKKTGWSLDDVDLVEVNEAFAVVSLVTMTKLEIPHEKLNVHGGACALGHPIGASGARILVTLLSALRQKGLKRGVAAICIGGGEATAMAVECLY
>NZ_CP051487.1|WP_020800544.1|3544928_3546056_-|acyl-CoA-dehydrogenase
MIPNDEQQQIRDAARDFAQERLKPFAAEWDREHRFPKEAITEMGELGFFGMLVPEQWGGCDTGYLAYAMALEEIAAGDGACSTIMSVHNSVGCVPILNYGNDDQKERFLKPLASGAMLGAFALTEPQAGSDASGLKTRARLDGDHYVLNGCKQFITSGQNAGVVIVFAVTDPSAGKRGITAFIVPTDSPGYKVARVEDKLGQHASDTCQILFEEVKVPVANRLGEEGEGYRIALANLEGGRVGIASQSVGMARAAFEAARDYARERESFGKPIIEHQAVAFRLADMATQIAVARQMVHYAAALRDSGKPALVEASMAKLFASEMAEKVCSSALQTLGGYGYLNDFPLERIYRDVRVCQIYEGTSDIQRMVISRNL
>NZ_CP051487.1|WP_020800542.1|3544086_3544860_-|enoyl-CoA-hydratase
MNYETILLETHGRVGLITLNRPQALNALNAQIVSELNHALDGFEADSNIGCIVLTGSKKAFAAGADIKEMAELTYPQIYIDDLFSDSDRVANRRKPIIAAVNGFALGGGCELALMCDFILAGDNAKFGQPEINLGVLPGMGGTQRLTRAVGKAKAMEMCLSGRLIDAVEAERCGIVARIVPSDELLDEALKVAALIAKKSLPIAMMVKESVNRAFEVSLSEGVRFERRVFHAAFATQDQKEGMAAFIAKREAEFQGK
>NZ_CP051487.1|WP_033042308.1|3542829_3543981_+|acyl-CoA-dehydrogenase
MHDLELTEEQVMIRDMARDFARGEIAPHAQAWEKAGWIDDALVAKMGELGLLGMVVPEEWGGTYVDYVAYALAVEEISAGDGATGAFMSIHNSVGCGPVLNYGSEEQKQTWLADLASGQVIGCFCLTEPQAGSEAHNLRTRAELRDGQWVLNGAKQFVSNGKRAKLAIVFAVTDPELGKRGISAFLVPTDTPGFIVDRTEHKMGIRASDTCAVTLDNCTIAEANLLGERGKGLAIALSNLEGGRIGIAAQALGIARAAFEAALTYSRERVQFGKTINEHQSIANLLADMHMQLNAARLMILHAARLRTAGKPCLSEASQAKLFASEMAEKVCSSAIQIHGGYGYLEDYPVEKYYRDARITQIYEGSSEIQRMVIARELKNYPL
>NZ_CP051487.1|WP_033042293.1|3541719_3542826_+|enoyl-CoA-hydratase/isomerase-family-protein
MTAEVLSKGTSSMVATQNEVLAEVRNHIGHLTLNRPAGLNAITLEMVRDLQRQLDAWAQDEQVHAVVLRGAGEKAFCAGGDIRSLYDSFKSGDTLHQDFFVEEYALDLAIHHYRKPVLALMDGFVLGGGMGLVQGADLRVVTEKSRLAMPEVGIGYFPDVGGSYFLPRIPGELGIYLGVSGVQIRAADALYCGLADWYLDSSKLATLDDRLDQLQWHDTPLKDLQGLLAKLGVQQLPDAPLAALRPAIDHFFALPDVPSIVEQMREVTVADSHEWATTTADLLQTRSPLAMGVTLEMLRRGRHLSLEQCFALELHLDRQWFERGDLIEGVRALLIDKDKNPRWNPPTLQALDAEHVASFFNGFDESGS
>NZ_CP051487.1|WP_168758180.1|3540864_3541572_+|HPP-family-protein
MLARWLPAAINTRPSEWSRAAIGMALGTMFSVWLCAQVFGMQVAQHLVGPLGASAVLLFAVSSGALAQPWSILGGYLSAAVVALLVAHVMGRTLGSACLAAGMALILMCWLRCLHPPAGALALLMVLADPATIAMDWKALGPVMLAALTMLFSALAYNNLTRIRYPKRASEPVAVVPADHPPVDSQAITAQDLKLALAQMEAFIDVTPEDLEQLIHATELQARRRSIGEVLSRSA
>NZ_CP051487.1|WP_155943756.1|3540722_3540866_-|hypothetical-protein
MMNIVPLKTEEKKGLAWETRKALEVVPTVGGGTATVCRAFPMLTNSY
>NZ_CP051487.1|WP_033044554.1|3553359_3554217_+|SDR-family-oxidoreductase
MNDYPKPPFPKQHQPVPGSQRKMDPYPDCGEQSYKGSGRLTGKIALITGGDSGIGRAVAIAFAREGADVAVAYLDEQEDAQETARWVEQAGRQCLLLPGDLAHKVHCRALVEKTVERFGRIDILVNNAAFQMTHENLEDIPDEEWVMTFDVNITAIFRICQAALKHMQPGSSIINTSSVNSDMPNPTLLAYATTKGAIANFTAGLAQMLGPKNIRVNSVAPGPIWTPLIVSTMPEETVQNFGANTPLGRPGQPVEVAPIYVLLASDEGSYITGQRFGVTGGKPIL
>NZ_CP051487.1|WP_168758183.1|3554343_3555693_+|sodium:proton-antiporter
MSFIAWVAVLGAVLLTLALTSSYLRWMPVTTSAVCLALGVGIGPAGLGWLRLDIKDAAFWMEHLTEVAVLFSLFVCGLKLRLPLRDRRWRVAFGLAGPVMVLTIIGVCLLLHYAFDLPWGPSLLIGAILAPTDPVLASLVQVNDAKDVDAVRFGLSGEAGLNDGIAFPFVILGLLFIEQGSGASTAWLDDWALKRLLWAVPAGLLVGYGMGRVIGRLTLSMRIRNADSTLSPNDYLTFALIALAYVAAESVHGYGFLAVFAAGLGLRRAEVKSMGYSQTPAEHLVQPVVGHQNVEPDAAVHGDVANLEEAQVAAGIMIGDMLSFGSLVERAMEVFLVTLLGVVLVGHWDWRALAVALVLFCVIRPLIVALVPWGTLLDGKQRLLIGWFGIRGIGSFYYLFYALNHNLAPTMATLCTDLTLSVVALSILIHGISTQPLLAHYERQKPPSA
>NZ_CP051487.1|WP_020800112.1|3555896_3556373_+|hemerythrin-domain-containing-protein
MNAIDLLKADHERVKGILSQLSESTERGLKKRADLLAKLEMEISIHTRLEEDVLYPAYKEAGGKEQDIMYYEAKEEHRTVDSLVLPDLKVTDPSTPEFAGRVKVVKELLEHHIEEEETTMFPQARKLLGKATLDELGAKMETLKARLKKELDASHMAA
>NZ_CP051487.1|WP_168758184.1|3556520_3558428_-|PAS-domain-S-box-protein
MSEDRIQARVIEDRRLRLLIDAVVDYAIYMIDPDGIITSWNAGARRFKGYEEAEILGQHFSRFYTDEDRRAGLPQRALDTAIREGRFEGEGWRVRKDGTHFWSHVVIDPIYDPSGTLLGFAKITRDLTDRKMAEETLKQSEQQFRLLVQSVTDYAIYMLAPDGRVTNWNLGAQRIKGYLPEEVIGQHFSMFYTPEDKASGLPGRALEIATREGRFENKGWRVRKDGTRFLAHVVVDPIWGDTGTLLGFAKITRDITEATQAQQALEQTREALFQAQKMQAIGQLSGGIAHDFNNLLTVILGNLEIVRKRLADDPKIVRLLDNATQGALRGVSLTQRMLAFARKQELKSEPVELPALVQGISGLLRSSLGPSVALETRFPERIEPVLADINQLELAMLNLATNARDAMPDGGKIVISARVETISDPLRAGRYVCLSITDTGDGMDEATLASAMDPFFTTKGLGKGTGLGLSMVHGFIEQLGGRFILKSQKNQGTTAELWLPVASEDSIAAPLAEEPATPEVPRLCILVVDDDSLVLTSTCLLLEDLGHQVITATSGAQGLEAFENNTGIDLVITDMAMPQMSGAQLAQAIRERNPDMPIILATGYAERLEGFAARLPRLSKPFTQLNLVEIIASAM
>NZ_CP051487.1|WP_168758185.1|3558435_3560748_-|ATP-dependent-DNA-helicase
MSYSIAVRALCEFTAKVGDLDLRFTPSPTALEGIVGHRTVASRRSDDYQSEVALEGAYQGLTVKGRADGYDPSQNCLEEIKTYRGDLSKQPANHRQLHWAQAKVYGWLMCRKLNLAQINLALVYFDIVSERETCLLEAFSAAELGQFFEHHCGLFLHWAEQETAHRQRRDLAARQLAFPHAEFRPGQRHLAESVFKAVSTGRCLMAQAPTGIGKTIGTLFPLLKALAPQQLDKLYFLTAKTPGRKLALDAAQVILDCSDAPPLRILEMIARDKACEHPDKACHGESCPLAQGFYDRLPAARQAASELGLLNQSALRQVALEHEVCPYYLSQEMARWADVVVADYNYYFDFSALLFGLAQANNWKVAVLVDEAHNLVERGRQMYSASLDQSTLDGVRKTAPEVLKKSLQRVNREWNALHNQQSAAYQAYDKPPEKLLQALSSCSASIGDYLNDHPQGLDSALQSFYFEVLQFCRVAELFDQQYLFDISKRDLDRKRNLSQLCLRNVVPAGFIGPRLSAARSTALFSATLSPRHYYADLLGTPANTVCIDVESPFHADQLHVQIINQISTRFVHRQASLAPIVELIARQFMRRPGNYLAFFSSFDYLQQVAQLLAERYPGINLWSQSRGMAEAQRQAFLDRFTAEGQGVGFAVLGGAFGEGIDLPGARLIGAFIATLGLAQLNPVNEQLKQRMAAMFGAGYDYTYLYPGVQKVVQAAGRVIRTQQDQGVVMLIDDRFGDNKVRQLLPRWWSIASAAVQMDGLSHTAELQHPM
>NZ_CP051487.1|WP_168758186.1|3560744_3562412_-|VRR-NUC-domain-containing-protein
MAPFPVTANPLDDPFYYLNNFMQVLDWLEQRYADVLSVEEHRFIHDFNGLPREAQALLVRLVMRKGVHFRVSKLHYVEIGDIASAARPLLELGWLDEHQPLSVEALFEVLLKAEILQCLGSAITQPKGKKTDWLPALCEQFPHEQSFKDWCPALGDRLFSLTIMGLCDRLRLMFFGNLYQDWSEFVLADLGVFTYEKVEFCADSRGLRSREDVDACLFLYQCQQLFEAGESVAAIVTQINGLALGNPWLQRRRDKLLFQMGQACERAGDFCAALTLYRDCVYPGARLRMIRVLERCGEYPLALDLACQAEQAPQNAAEQQHLLRVLPRLRRKLGGPAVKRPAPRQMERLELQLSRTDPMLSVEDYVQAHLGEDSAPVHYVENSLVNSLFGLLCWPAIFAPLPGAFFHPFQRGPVDLLSEDFHSRRAELFQACLDELDDGRYLETIRLRYAQKWGVQSPFVFWGALSEPLLEQALDCLPAEHLKHWFNRLLLDIKANRAGMPDLIQFWPQEKTYRMIEVKGPGDRLQDNQLRWLEFCHEHRMPIAVCYVQWAEQGA
>NZ_CP051487.1|WP_020800116.1|3562608_3562833_+|YgdI/YgdR-family-lipoprotein
MNIKTLAFPMAVAAFIALAGCSTPTVVTLQNGTQYLTKDMPKTKTKDGFFEFEDISGAKVKVKADDVATIRQED
>NZ_CP051487.1|WP_168758187.1|3562930_3563590_+|hypothetical-protein
MKMVTPLLTPLLAVAAWFSMSLCANAATPARSFNTSFDCAAARGAVEKLICRDARLAQMDIELTRLYRLALTDEHSVPRPDKVEIDQRFWLLARDQCATEADPKACTVSHYAERAHQLRQGSAIARTKDPSRLTEGPQAFRCAGLGALVAATFFTVEPAVVYLKWANTSTTLEQVPSSSGALYQGKDNRGSQSFWQNGNDALLRMPGAGEMRCTVEPVS
>NZ_CP051487.1|WP_168758188.1|3563616_3565023_-|FAD-dependent-oxidoreductase
MPAWRTISLWMDQLDEPLLARAALERDLDVDVAIIGAGYTGLWTAYYLKRQAPGLNIVIIEAQTAGFGASGRNGGWLMGNLLGEDRLLASLSPEQRRASYDLLHDIPDEVKRVIEREGIDCDYRKGGALYCAARYPEQEATLRQYLDKLYGQGLNENDYRWLSPEQMAQQICLAKPYGAIYAPHVATLHPAKLVRGLARAVERMGVRIYENSPVNHWQSGSVRTAQATVRSRWVVPAVEGYSVTLPPLGRYQLPVQSLIVATEPLSAATWDEIGLSHGQAFSENSRQVTYGQRTADNRLIFGARGGYQFAGKLRHDFDLTRSEIELRRYLFGELFPQLRNVQITHGWGGNLGMSRHFKPHMLCDQASGIALSGGYGGEGVGASNLGGRTLADLILQRDTERVRQPWVIAKGGLHALKAWEPEPWRWLGYNAIIRSFVHEDQTLANPTSAPWRRRLASGVAGFMEGLMH
>NZ_CP051487.1|WP_168758189.1|3565073_3565889_-|helix-turn-helix-domain-containing-protein
MYAEDDGPLQTQATGETVMLYHLRWKHRDLDGVMALYHPDVRYSDFFQNRVMGLAQLRDYVQSSMPREPDEALEHSDRIRLDGNTAFIQYRITLRGGEGLVSFRASEAITVKDGLIWRVNEYASLVHERPCGENTGSQRPAVSRLGLSVRQLSFMADDLQQYFQRQQPYLDPRLDLQRVAQECGYSRNQISYLLNQVLGQSFYRYVNQARLQHLLNALDSAMPAVRIDALAFAAGFNSLSAFYSCFRQHTGLSPKAYVKQMSLRARAQDST

Crispr_ID: NZ_CP051487_8

• CRISPR_ID: NZ_CP051487_8
• CRISPR_location: 4116963-4117069
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_8

Consensus_repeat	Method
GCCAGCTCCCACAGTAGATCGAGTACATTCGTCAGCG	CRISPRCasFinder

spacers of NZ_CP051487_8

>8.1|4117000|33|NZ_CP051487|CRISPRCasFinder
ACTGGTTGGCTGCAAGGCCGCCTTCGCTGGCAG

CRISPR arrays and Neighbor proteins around NZ_CP051487_8

CRISPR arrays

The CRISPR arrays of NZ_CP051487_8

>merge|NZ_CP051487|8|4116963-4117069|CRISPRCasFinder
GCCAGCTCCCACAGTAGATCGAGTACATTCGTCAGCGACTGGTTGGCTGCAAGGCCGCCTTCGCTGGCAGGCCAGCTCCCACAGTAGATCGAGTACATCCGTCAGCG

>NZ_CP051487|8|8|4116963-4117069|CRISPRCasFinder
GCCAGCTCCCACAGTAGATCGAGTACATTCGTCAGCG	ACTGGTTGGCTGCAAGGCCGCCTTCGCTGGCAG
GCCAGCTCCCACAGTAGATCGAGTACATCCGTCAGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_033039089.1|4110196_4111588_-|oligosaccharide-flippase-family-protein	unknown	unknown	gnl|CDD|240532
NZ_CP051487.1|WP_033039823.1|4104342_4105266_-|DUF535-family-protein	unknown	unknown	gnl|CDD|377343
NZ_CP051487.1|WP_033039832.1|4105273_4106251_-|glycosyltransferase	unknown	unknown	gnl|CDD|133029
NZ_CP051487.1|WP_020799625.1|4106256_4106781_-|serine-acetyltransferase	unknown	unknown	gnl|CDD|223975
NZ_CP051487.1|WP_020801142.1|4120053_4121097_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|366009
NZ_CP051487.1|WP_168758358.1|4108467_4109934_-|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NZ_CP051487.1|WP_168758362.1|4124767_4126093_-|ammonium-transporter	unknown	unknown	gnl|CDD|223083
NZ_CP051487.1|WP_020799630.1|4111691_4113218_+|O-antigen-ligase-family-protein	unknown	unknown	gnl|CDD|377422
NZ_CP051487.1|WP_020799632.1|4115925_4116903_+|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl|CDD|224012
NZ_CP051487.1|WP_168758359.1|4113223_4115854_+|cellulase-family-glycosylhydrolase	unknown	unknown	gnl|CDD|225344
NZ_CP051487.1|WP_008061453.1|4119387_4119873_+|flavin-reductase-family-protein	unknown	unknown	gnl|CDD|214900
NZ_CP051487.1|WP_168758360.1|4117657_4119064_-|cytosine-permease	unknown	unknown	gnl|CDD|271377
NZ_CP051487.1|WP_020801138.1|4123744_4124650_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl|CDD|172682
NZ_CP051487.1|WP_020801136.1|4126219_4127542_-|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl|CDD|239202
NZ_CP051487.1|WP_020799627.1|4107738_4108356_-|acyltransferase	unknown	unknown	gnl|CDD|100053
NZ_CP051487.1|WP_020801141.1|4121229_4121385_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP051487.1|WP_168758361.1|4122160_4123522_+|cytosine-permease	unknown	unknown	gnl|CDD|224374
NZ_CP051487.1|WP_151142666.1|4127562_4128246_-|protein-glxC	unknown	unknown	gnl|CDD|223148
NZ_CP051487.1|WP_020801140.1|4121477_4122155_+|cysteine-hydrolase	unknown	unknown	gnl|CDD|238245
NZ_CP051487.1|WP_168758357.1|4106789_4107746_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133029

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_033039089.1|4110196_4111588_-|oligosaccharide-flippase-family-protein	gnl|CDD|240532	cd13127, MATE_tuaB_like, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	7.69442e-47
NZ_CP051487.1|WP_033039823.1|4104342_4105266_-|DUF535-family-protein	gnl|CDD|377343	pfam04393, DUF535, Protein of unknown function (DUF535). Family member Shigella flexneri VirK is a virulence protein required for the expression, or correct membrane localization of IcsA (VirG) on the bacterial cell surface,. This family also includes Pasteurella haemolytica lapB, which is thought to be membrane-associated.	1.05377e-73
NZ_CP051487.1|WP_033039832.1|4105273_4106251_-|glycosyltransferase	gnl|CDD|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	9.88987e-18
NZ_CP051487.1|WP_020799625.1|4106256_4106781_-|serine-acetyltransferase	gnl|CDD|223975	COG1045, CysE, Serine acetyltransferase [Amino acid transport and metabolism].	2.86889e-42
NZ_CP051487.1|WP_020801142.1|4120053_4121097_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|366009	pfam00296, Bac_luciferase, Luciferase-like monooxygenase.	3.49172e-56
NZ_CP051487.1|WP_168758358.1|4108467_4109934_-|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	3.12604e-38
NZ_CP051487.1|WP_168758362.1|4124767_4126093_-|ammonium-transporter	gnl|CDD|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	7.57608e-158
NZ_CP051487.1|WP_020799630.1|4111691_4113218_+|O-antigen-ligase-family-protein	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	7.15358e-08
NZ_CP051487.1|WP_020799632.1|4115925_4116903_+|UDP-glucose-4-epimerase-GalE	gnl|CDD|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	0
NZ_CP051487.1|WP_168758359.1|4113223_4115854_+|cellulase-family-glycosylhydrolase	gnl|CDD|225344	COG2730, BglC, Endoglucanase [Carbohydrate transport and metabolism].	0.0060628
NZ_CP051487.1|WP_008061453.1|4119387_4119873_+|flavin-reductase-family-protein	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	4.65722e-54
NZ_CP051487.1|WP_168758360.1|4117657_4119064_-|cytosine-permease	gnl|CDD|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	4.46753e-66
NZ_CP051487.1|WP_020801136.1|4126219_4127542_-|FMN-binding-glutamate-synthase-family-protein	gnl|CDD|239202	cd02808, GltS_FMN, Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast and bacterial pathway for ammonia assimilation. It is a multifunctional enzyme that functions through three distinct active centers, carrying out L-glutamine hydrolysis, conversion of 2-oxoglutarate into L-glutamate, and electron uptake from an electron donor.	2.86027e-161
NZ_CP051487.1|WP_020799627.1|4107738_4108356_-|acyltransferase	gnl|CDD|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.6018e-31
NZ_CP051487.1|WP_020801138.1|4123744_4124650_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl|CDD|172682	PRK14194, PRK14194, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	8.22665e-161
NZ_CP051487.1|WP_168758361.1|4122160_4123522_+|cytosine-permease	gnl|CDD|224374	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism].	2.13688e-90
NZ_CP051487.1|WP_151142666.1|4127562_4128246_-|protein-glxC	gnl|CDD|223148	COG0070, GltB, Glutamate synthase domain 3 [Amino acid transport and metabolism].	2.51484e-40
NZ_CP051487.1|WP_020801140.1|4121477_4122155_+|cysteine-hydrolase	gnl|CDD|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	3.45567e-53
NZ_CP051487.1|WP_168758357.1|4106789_4107746_-|glycosyltransferase-family-2-protein	gnl|CDD|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	6.58023e-51

Protein sequences

>NZ_CP051487.1|WP_020799632.1|4115925_4116903_+|UDP-glucose-4-epimerase-GalE
MKFLVIGGAGYIGSHMVKQLLGAGHELVVADNFSTGYRSALLGGTLVELDIADAQALDALFASHHFDAVFHFASFIQVGESVTEPAKYYQNNLAATLTLLKAMVRAGVKRFIFSSTAAVYGDPQYVPIDEAHPKAAINPYGRTKWMVEQMLEDFDRAYGLKSVCLRYFNAAGADPDGQLGERHEPETHLLPLILQAASGRRKTITVYGFDYDTPDGTCIRDYIHVCDLVAAHALAVDYLFKGGSSTAFNLGNGQGFSVQQVIDTARRVTGRDIYIGEASRRAGDPPRLVADASRANTLLGWRPQYARLEQIVAHAWEWERKYPWH
>NZ_CP051487.1|WP_168758359.1|4113223_4115854_+|cellulase-family-glycosylhydrolase
MTCFFYRMPLLSVFLLTVAIWPLSTRAAEWVASVDERSGLPQVTRGGSPAMASQFVFWGGNWDWADFTPSLKVISPFVYAMEGKSQKLDFDATGQIRKQDEQTLSINLVLDARSLKTNVMGGGIVFNFDPALAEAMGEPVLLPGNRGWTWGNAQGRRIEMRFEPALARVYFEPGDRSQVRAFLYKDRIKPGRENFKATFSVSGDVVLGPTAAERFGIADPKSWPSDRLDWKTAPVDLSFLNAPEKPAGKRGFVKAVGEQLLFADNTPARFWGTNLSAYTLFQTPDDAIKLQAKRLSALGFNLVRLHHHDSWWVLPNIFGDGRKVHDTQRLSEESLKKLDLWIKSLKDEGIYVWLDMHVQRALWANDNIFAFDELPKNEYGIADLKGYAYVNETIQRAMKRFAKDYLSHVNSYTGLAYKDDPAVAAVLITNENDITQHYGNALLPDKSVPKHNELYMKAAKAFAKQHNLPEDQTWRSWEPGPAKLFLNDLERRFNVDMIESLRETGVKVPIATTSSWGGNGLSALPALTAGDVVDVHIYGGPGTLEKNPLASASLVDWIGAGQVVGKPLTVTEWNNEPFPIADRHSLPLYMAGTASHQGWDALMQYAYSQEPLTEQSESAGNWHAYNDPAMLATLPAAALLYRRGDVHEAKTTYVFAPTPETLFNQRITPDSSALLRTAMEKGKLQIAMPQTPQLPWLQPGIIARNAQVFHDPAQSLLDATASESTTDTGELKRNWKQGLYTIDTPRTQAATGWIGGNSIQLGNIQVQLKTAYASVVVQSLDGVPVGKSADLLISLGTRAVPKDNDKTPFHVEPLEGTLSIQAPPGLTLFTQGGPLGQLGKLPATYLDGRYTIKFDGLQASNWLFLKKASQASENLK
>NZ_CP051487.1|WP_020799630.1|4111691_4113218_+|O-antigen-ligase-family-protein
MPEHFRALVVILVLAGIVFAFARRPAADLIPLSDFTRRRNLWFGLTLLAFFSHSFWVYAGVTAIILAVTRQRERNPLALFFMLLFLIPPANAQVPGFGLVNYLFDLNHVRLLALCVLLPAFLALRKRPDTLPFGRTLPDKLLLAYLLLTSALFLRQTTPTDTLRQSLYLFVDVFLPYYVASRSMKNVSDFKDALLAFLLAAMLLSLIGLFEYTRRWLLYNGLTYAMGVQWEIATYLSRGGSLRASVTTGQAIALGYVIAVAIGFYLFLQEGVRSKLQRRLGALLLAGGLFAPLSRGPWIGAAVMIVMFIGTGRYAVRRLVLLGGAALLALPLLAILPGGQKILDLLPFIGSVEVENITYRQRLIDNSLIVIQRNPWLGSFDYRSTPEMQSMIQGQGIIDIVNTYIGIALQMGFIGLTLFVAFFATIALGIRKAMRSFPKQEDESRRLGRALLATLAGILVTIITVSSITVIPVVYWSVAGLGVSYAQMARRLKRAETASSKSTLLQTW
>NZ_CP051487.1|WP_033039089.1|4110196_4111588_-|oligosaccharide-flippase-family-protein
MPSVNISPTFSLRRRAISAGAWNLGALVTSQVIRLGGNLVMTRLLMPEMFGIIAIATTVLFVLHLLSDVGLRQNILQSPRGDDPVFLNTLWTVQIVRGFVLFAFTLLLAAAAWYSQVIDFWSHNSTYAAPELPMVLAWTGVTAIIYGFQSTKVDLAVRAFQQKKVVIAEFVSQVVGLLVMLVIGYFTHSIWSLVAAGLVTALVSTLLGHFWFEGPSNSLRWERAALHELMVFGRWILLSSAVGVLSMQGDRIIFGGSMTVFEMGVYSIAVLILGALQTGVLKVVGAVALPAFGEAARTNDFERLRSLYYRFKMMVDVALLFLCGFLWVTSPLIIKVLYDDRYAQAGHMMAVLSTSFFVMRYIVANQIWIALGLTKYQAIDNIIRVVSLWVLVPLLLAFGGVDWAIWGVALHTLPTLVLVVYVNRRVGILDIKRELIVLPMLVVGALCGELVLVVFKWLFDLSA
>NZ_CP051487.1|WP_168758358.1|4108467_4109934_-|GMC-family-oxidoreductase
MIKDYQTQKDLRDHYDFCIVGAGPAGITLALRLAGNGWRVVLLEGGGREYAAYSQNLYKCPSTGLDVFAEETRLRYLGGTSNHWAGRCRPFEPSDFALSPPVNLPGWPIAFSEMERNLPAAMAILDLPLDSGFKTVNAAFKSDEFEADRFLLSPPTRFAQKYAKELEETEGLDVFINCNCVDLDFDSNTGRITAVVVSDYERQQERVSAKQFILATGAIENARQLLNSKSLAAAGVITEDGLVGRCFMEHLNIALGTFILNEGESREARQFFTKDAFVVEHHSGKGNVTASLVSAVETYGRLAAIKGFFENLACKAGMAHKIEFIAKFNCPGDGELGTMIEQFPNRKSRVSLTQEHDDLGMRMVNVHWELAPEDRETIKSIGLEVAKCFAEEGLGYVKLEEAVYDVSLPLKVVPHAHHMGTTRMASSPEFGVVDENSKVFGTNNLYVAGSSVFATAGASNPTMPLLQLTLRLADYLNHQMGPAAGRYS
>NZ_CP051487.1|WP_020799627.1|4107738_4108356_-|acyltransferase
MIGLAKRAIRYYVNKTGRGKGLFKKFCHPTGFEWANYLARWGGIHSVGKGVWINPGCNIPDPSLLRIGNNVGLSDCTIFGHDGLIGVFEISAGKQLDSVGAVDIFDNCFIGYQAIVMPGRKIGPNSIVAAGAVVTRDVPPGVVVGGNPAKVLCTVEDLIKKIEERCEAYPWMELIRQRGTHFDPDYEPKLKAMRAQYFFGEKANE
>NZ_CP051487.1|WP_168758357.1|4106789_4107746_-|glycosyltransferase-family-2-protein
MSSAPLDVLVVNYNTAGLLQPMFNALRQSKSTDHARYLVVDNASADNSLDCLGDICPEAVLLANKDNVGFGRANNQLVEHLQGKYALLLNTDAFVSDDTLAKTLEYMEAHPDCGILGVRLVGRDGEMQPSCRYFPTPLNVFLVTAGLERFFPWVKLVDDLDWDHASVRECDWVPGCYYLIRREVIDKVGLFDPRYFLYYEEVDHCRRVKEAGWKVVYYPHTSVVHIGGESAKSVDKLNMDGRQLQTLQIESELLYFRKHHGLPGLALHMLLVCLCDLILGLKALLKGRGRAAIKACWQHTRVTWALLRKTKLGSQPTR
>NZ_CP051487.1|WP_020799625.1|4106256_4106781_-|serine-acetyltransferase
MFENIRADLRAYEGDWGAQGFWVMLVYRFGRWRYGVRPALLRKLLSFIYKVLFKLVQIVTGIELPCEVVVGRNFVIDHFGGIVISGYAQFGDDCRIRNGVVVGLKNVKEPIAPVMGNNVDIGTGAKVLGNIRIGNNVVIGANAVVLTDVPDNSVAVGVPATIKQRKLADAEQFS
>NZ_CP051487.1|WP_033039832.1|4105273_4106251_-|glycosyltransferase
MTTGVGVVVIGRNEGQRLERCLASLVGAAQQIVYVDSGSTDGSVQMARRLGVEVVELDMSIAFTAARARNEGFARLQRLLPSMRHVQFVDGDCEVVASWLPHAQAFLEARPEVAVVCGRRRERFPQRSIYNLMCDLEWDTPTGATSACGGDALMRADAFATAGGYRPDLIAGEEPELCVRLRAKGWKVWRLPAEMTLHDASMTRFGQWWRRTLRGGYAFAEGAFLHGGAPERHWRRESRRAWFWGLGVPLATVIATLLLGWPGLLLLLIYPLQVARLARRGAGPARQNWLLAFFLVLGKFPEMFGQVKFLLNRFGAGKSALIEYK
>NZ_CP051487.1|WP_033039823.1|4104342_4105266_-|DUF535-family-protein
MDYWMIVKSVFSVHAGYSLRALKNKLKFVLLVGKNWTELNLFFGRMSNALGDTGIERLGGDCLGVIHWPYISKSWNSQDKLGVMASHYEVVTKSCPQLLLFGRDDSLVLSDLTAWSDGCTLVLDRPFWFMREGELVLNLFQGDLRIASIAFTLCCTEGELCIFIGAVQGIHKGIESERSLAIYRDVTKDFEGLRPRSFLIEVIKYIASHIGVGKIYAVGDVYRHHRHPYFGAHKAQELAANYDSIWLEHGATPSAREDFFEIPMASSRKPLETIASKKRAMYRRRYELLDDTFTRIDQVLKGSYAVN
>NZ_CP051487.1|WP_168758360.1|4117657_4119064_-|cytosine-permease
MSQMSRQDPLIENHTVDYVPLAERHGKARDLFTLWFSTNIAPLPIVTGAMVVQVFHLDMFWGLLAIALGHMVGGLVIALASAQGPRMGIPQMVQSRGQFGRYGALLIVFFAALIYIGFFISNIVLAGKSIVGIAPSVPVPASILIGALSATAIGVIGYRFIHSLNRIGTWVMGSALLAGFLYIFAHDLPADFFTRGGFNLSGWLATVSLGIIWQISFSPYVSDYSRYLPADIGIAKPFWATYLGATLGTILSFTFGAVAVLATPEGTEAMAAVKQSTGWLGPILMVLFLLNIISHNALNLYGAVLSIITSIQTFASQWTPSIKVRVMLSSGVLAGCCVVALGASADFISQFIGLILALLLVLVPWASINLIDFYVIKRGRYDIASIFRADGGMYGRFNLHAIVAYFIGIIVQLPFANTSLYVGPYANLVEGADLSWLVGLVVTCPLYYCLATRGRTQEGRASELSYTD
>NZ_CP051487.1|WP_008061453.1|4119387_4119873_+|flavin-reductase-family-protein
MIDAAIYKQVMGSFPSGVCVITTLDDDGQVVGLTASAFSSLSMDPALVLFCPNYSSDSYPVLIRNKRFAIHVLSGGQQSEAYAFARKGKDKAQGIEWTLSELGNPILANATAVIECELWREYEGGDHAIMVGAVKNLIVPQHNAGPLVYCHGKMGALPVLA
>NZ_CP051487.1|WP_020801142.1|4120053_4121097_+|LLM-class-flavin-dependent-oxidoreductase
MKFSLFVHMERWDESVSHRQLFEDLTELTLMAEAGGFSTVWIGEHHAMEYTISPSPMPLLAYLAGKTTTIHLGAGTIIAPFWHPIRVAGECALLDVISNGRMEVGLARGAYQVEFDRMAGGMPASSGGQALREMVPVVRALWQGDYAHDGDIWKFPTSTSVPKPIQKPNPPMWIAARDPDSHNFAVANGCNVMVTPLMKGDEEVLDLKNKFQTALDNNPDVPRPQLMVLRHTHVHSVDNPEGWKVGAKAIAKFYRTFDAWFGNKETPVNGFLAPSPEEKFAGRPEFELESLHKTAMIGTPEEIIPRIKYYQELGVDEFSFWCDNSLPHAEKKKSLELFIKHVVPAFR
>NZ_CP051487.1|WP_020801141.1|4121229_4121385_+|hypothetical-protein
MLNNGHLRSLPLPSGAAQAYLRGEWTASHIHLKRLPASVSAKQNGFWQPVY
>NZ_CP051487.1|WP_020801140.1|4121477_4122155_+|cysteine-hydrolase
MNNNNALLIIDMQQEDGFVLEHFDKVVANTAYLLDTARQQRVPILYTRHINQADGNDLPRGEPRACDGGPSGYRAGTRQVEIIERLAPRPDEAIIDKGRYSAFHRTDLDARLKALDVDTLIISGVLTDVCVLTTVFDAFALGYHTRLVSDACTTTTLAGHYSALLIMVNWVYSLEILTSSECRRALQNLDYLSLNPEHPDLFAHQPHELPGTIARLQNHLVRTQE
>NZ_CP051487.1|WP_168758361.1|4122160_4123522_+|cytosine-permease
MQVEKRSIDFIPEAERHGRPGSLFFIWFGANMNITTIASGVLPVVMGLNLFWSALAIVVGSLLGAIFMASHSAQGPKLGIPQMIQSRAQFGVLGAVLPLLFVMLIYLGFFVSNTLLAAQALESVSPLPASGNIYLIGALCFVVALYGYRLIHRLQKLLSILSLLVFAAATLLALQLTIPAEQWLPTGFSLSKFLVAVSIAVTWQLSYAPYVADYSRYLPSRASAAQVFWYSYAGTVSGGAWMMILGAILSVGIGDFSSNVGGHVAGLFGSGAILLFAFIVYGQVSINVFNLYGAFMSTITVIEPFARLKVTPRVRGLFMLVISVIATGLCTISQDDFITFFLNFIFFMSYFLIPWTAINLVDFYCLRKGEYRIDDIFDLNGIYGRVNWIACGSFVLAIALEIPFMNTTLYVGPVATALDGVDLAWLVGLLVPALSYYWLMKLGKRAERIGELS
>NZ_CP051487.1|WP_020801138.1|4123744_4124650_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MTSTNPALARDIDGKAISAKVLDEVREEVQVLARQQIYPALAVLLVGEDPASEVYVRNKLLRAKEVGIRSLEYRLPEIASQNDVLQLIAQLNADVTVNGILVQLPLPAHIDEAAVIHAIDPIKDVDGFHRENVGGLVQGIEVLTPCTPSGCMRLLQETCGDLSGLHAVVIGRSNIVGKPMATLLLQADCSVSVVHSRSVDAPTLCRMADIVVVAVGRPQMIDASWLKPGAVVIDVGINRITTASGTRLVGDVDYASARTVASAITPVPGGVGPMTIAYLLKNTLVASQLQRGVRTRHSMPL
>NZ_CP051487.1|WP_168758362.1|4124767_4126093_-|ammonium-transporter
MVNRLLGKSLVGLLASGALVSLAQAADAPALNTGSTAWMVTATVLVLFMCLPGLALFYGGLVRAKNMLSLFTQCFGIAGLVGVLWVIYGYSMVVDTTGMVEGEVSFNSFVGGMSRAFLSGMTPQSLVGEIPEGVFVTFQMTFAIITPALIAGAFAERMKFSAALLFMALWFTLVYAPVAHMVWGGAGALMHNWGVLDFAGGTAVHINAGVAALAACLILGKRKGYENTPMPAHNLSLTMAGAAMLWVGWFGFNIGSGGGLSGTSGIVMLNTQLGACAGILGWMFTEWFKVGKPSALGLASGALAGLVGITPACAYVGVGGALAIGLLCGVFCYLSVTVLKRRFGYDDSLDVFGLHGIGGMIGAVLTGVFCVPSLGGLVEGVSMGGQVLAQIKGVALTTVYCFVISWIILKVVNVVVGLRADESVEELGLDLGEHNERAYNH
>NZ_CP051487.1|WP_020801136.1|4126219_4127542_-|FMN-binding-glutamate-synthase-family-protein
MNEKTPPVLRESATFDRLTIQEIQRAAETGIYDIRGGGTKRKVPHFDDLLLLGASVSRYPLEGYREKCGTDVILGNRFAKKPIHLKIPVTIAGMSFGALSANAKEALGRGATIAGTSTTTGDGGMTPEERGQSQHLVYQYLPSRYGMNPDDLRKADAIEIVLGQGAKPGGGGMLLGMKVTERVAGMRTLPIGVDQRSACRHPDWTGPDDLAIKIAEIREITDWEKPIYVKIGASRPYYDVKLAVKAGADVIVLDGMQGGTAATQEVFIEHVGIPILPAIPQAVQALQEMGMHRKVQLIVSGGIRNGADVAKAMALGADAVAIGTAALIALGDNHPRLDEELHKIGSAAGFYDDWQNGRDPAGITTQDPELSKRLDPVEGGRRLANYLRVLVLEAQTMARACGKSHLHNLDPEDLVALTVESAAMARVPLAGTSWIPGSGF
>NZ_CP051487.1|WP_151142666.1|4127562_4128246_-|protein-glxC
MKTIDLSIASVRDLNQALHDQVHNVEDREWVVTHANGKHNLAVGVNQAVSIDIQGHAGYYCAGMNQQASITVHGNAGVGVAENMMSGVVRIKGSASQAAGATAHGGLLVIEGDAGARCGISMKGIDIVVGGSIGHMSCFMGQAGRLVVCGDAGDALGDSLYETHIYVKGKVASLGSDCIEKEMRAEHLEELQVLLKRAGFEHKAADFKRYGSARQLYNFKVDNASAY

Crispr_ID: NZ_CP051487_9

• CRISPR_ID: NZ_CP051487_9
• CRISPR_location: 4431863-4431940
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_9

Consensus_repeat	Method
GCTGAAGGTGGCGCCGATCGCCTG	CRISPRCasFinder

spacers of NZ_CP051487_9

>9.1|4431887|30|NZ_CP051487|CRISPRCasFinder
AGAGAACGGCAGCTCAAGCAAAATCAGGTC

CRISPR arrays and Neighbor proteins around NZ_CP051487_9

CRISPR arrays

The CRISPR arrays of NZ_CP051487_9

>merge|NZ_CP051487|9|4431863-4431940|CRISPRCasFinder
GCTGAAGGTGGCGCCGATCGCCTGAGAGAACGGCAGCTCAAGCAAAATCAGGTCGCCGAAGGTGGCGCCGATCGCCTG

>NZ_CP051487|9|9|4431863-4431940|CRISPRCasFinder
GCTGAAGGTGGCGCCGATCGCCTG	AGAGAACGGCAGCTCAAGCAAAATCAGGTC
GCCGAAGGTGGCGCCGATCGCCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_151142734.1|4442647_4444156_+|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl|CDD|225821
NZ_CP051487.1|WP_168758520.1|4427866_4428634_+|heme-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|237422
NZ_CP051487.1|WP_151144103.1|4434529_4434847_+|NIPSNAP-family-protein	unknown	unknown	gnl|CDD|311781
NZ_CP051487.1|WP_020796887.1|4441663_4442578_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP051487.1|WP_033045137.1|4430262_4431012_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|223774
NZ_CP051487.1|WP_168758523.1|4434848_4435307_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP051487.1|WP_020796902.1|4431067_4431472_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380362
NZ_CP051487.1|WP_083349361.1|4426102_4426363_+|transmembrane-sensor/regulator-PpyR	unknown	unknown	unknown
NZ_CP051487.1|WP_020796888.1|4440512_4441511_-|agmatinase	unknown	unknown	gnl|CDD|212537
NZ_CP051487.1|WP_168758521.1|4428660_4429545_+|iron(III)-ABC-transporter	unknown	unknown	gnl|CDD|225561
NZ_CP051487.1|WP_168759201.1|4435466_4437155_-|choline-dehydrogenase	unknown	unknown	gnl|CDD|235000
NZ_CP051487.1|WP_168758522.1|4433291_4434197_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176163
NZ_CP051487.1|WP_033043392.1|4424319_4424694_+|response-regulator	unknown	unknown	gnl|CDD|381092
NZ_CP051487.1|WP_020796904.1|4429665_4430055_-|cytochrome-c-family-protein	unknown	unknown	gnl|CDD|226005
NZ_CP051487.1|WP_168758524.1|4438929_4440441_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143410
NZ_CP051487.1|WP_020796911.1|4424847_4426050_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224172
NZ_CP051487.1|WP_083349367.1|4432330_4433161_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|180446
NZ_CP051487.1|WP_083349358.1|4423567_4424221_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|226932
NZ_CP051487.1|WP_168759199.1|4426883_4427867_+|iron-ABC-transporter-permease	unknown	unknown	gnl|CDD|376439
NZ_CP051487.1|WP_020796890.1|4437172_4438747_-|purine-cytosine-permease-like-transporter	unknown	unknown	gnl|CDD|271377

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_151142734.1|4442647_4444156_+|sigma-54-interacting-transcriptional-regulator	gnl|CDD|225821	COG3283, TyrR, Transcriptional regulator of aromatic amino acids metabolism [Transcription / Amino acid transport and metabolism].	0
NZ_CP051487.1|WP_168758520.1|4427866_4428634_+|heme-ABC-transporter-ATP-binding-protein	gnl|CDD|237422	PRK13548, hmuV, hemin importer ATP-binding subunit; Provisional.	1.40489e-131
NZ_CP051487.1|WP_151144103.1|4434529_4434847_+|NIPSNAP-family-protein	gnl|CDD|311781	pfam07978, NIPSNAP, NIPSNAP. Members of this family include many hypothetical proteins. It also includes members of the NIPSNAP family which have putative roles in vesicular transport. This domain is often found in duplicate.	4.31503e-26
NZ_CP051487.1|WP_020796887.1|4441663_4442578_+|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	9.49677e-34
NZ_CP051487.1|WP_033045137.1|4430262_4431012_+|SDR-family-oxidoreductase	gnl|CDD|223774	COG0702, COG0702, Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	7.04981e-26
NZ_CP051487.1|WP_168758523.1|4434848_4435307_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.86561e-17
NZ_CP051487.1|WP_020796902.1|4431067_4431472_+|cupin-domain-containing-protein	gnl|CDD|380362	cd02234, cupin_BLR7677-like, Bradyrhizobium japonicum BLR7677 and related proteins, cupin domain. This family includes bacterial and fungal proteins homologous to BLR7677, a Bradyrhizobium japonicum protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	9.59166e-45
NZ_CP051487.1|WP_020796888.1|4440512_4441511_-|agmatinase	gnl|CDD|212537	cd11589, Agmatinase_like_1, Agmatinase and related proteins. This family includes known and predicted bacterial agmatinase (agmatine ureohydrolase; AUH; SpeB; EC=3.5.3.11), a binuclear manganese metalloenzyme, belonging to the ureohydrolase superfamily. It is a key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield urea and putrescine, the precursor for biosynthesis of higher polyamines, spermidine, and spermine. Agmatinase from Deinococcus radiodurans shows approximately 33% of sequence identity to human mitochondrial agmatinase. An analysis of the evolutionary relationship among ureohydrolase superfamily enzymes indicates the pathway involving arginine decarboxylase and agmatinase evolved earlier than the arginase pathway of polyamine.	1.73127e-153
NZ_CP051487.1|WP_168758521.1|4428660_4429545_+|iron(III)-ABC-transporter	gnl|CDD|225561	COG3016, PhuW, Uncharacterized iron-regulated protein [Function unknown].	8.01681e-80
NZ_CP051487.1|WP_168759201.1|4435466_4437155_-|choline-dehydrogenase	gnl|CDD|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_CP051487.1|WP_168758522.1|4433291_4434197_+|LysR-family-transcriptional-regulator	gnl|CDD|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.84069e-103
NZ_CP051487.1|WP_033043392.1|4424319_4424694_+|response-regulator	gnl|CDD|381092	cd17537, REC_FixJ, phosphoacceptor receiver (REC) domain of FixJ family response regulators. FixJ family response regulators contain an N-terminal receiver domain (REC) and a C-terminal LuxR family helix-turn-helix (HTH) DNA-binding output domain. The Sinorhizobium meliloti two-component system FixL/FixJ regulates nitrogen fixation in response to oxygen during symbiosis. Under microaerobic conditions, the kinase FixL phosphorylates the response regulator FixJ resulting in the regulation of nitrogen fixation genes such as nifA and fixK. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.58856e-27
NZ_CP051487.1|WP_020796904.1|4429665_4430055_-|cytochrome-c-family-protein	gnl|CDD|226005	COG3474, COG3474, Cytochrome c2 [Energy production and conversion].	1.1565e-38
NZ_CP051487.1|WP_168758524.1|4438929_4440441_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143410	cd07091, ALDH_F1-2_Ald2-like, ALDH subfamily: ALDH families 1and 2, including 10-formyltetrahydrofolate dehydrogenase, NAD+-dependent retinal dehydrogenase 1 and related proteins. ALDH subfamily which includes the NAD+-dependent retinal dehydrogenase 1 (RALDH 1, ALDH1, EC=1.2.1.36), also known as aldehyde dehydrogenase family 1 member A1 (ALDH1A1), in humans, a homotetrameric, cytosolic enzyme that catalyzes the oxidation of retinaldehyde to retinoic acid. Human ALDH1B1 and ALDH2 are also in this cluster; both are mitochrondrial homotetramers which play important roles in acetaldehyde oxidation; ALDH1B1 in response to UV light exposure and ALDH2 during ethanol metabolism. 10-formyltetrahydrofolate dehydrogenase (FTHFDH, EC=1.5.1.6), also known as aldehyde dehydrogenase family 1 member L1 (ALDH1L1), in humans, a multi-domain homotetramer with an N-terminal formyl transferase domain and a C-terminal ALDH domain. FTHFDH catalyzes an NADP+-dependent dehydrogenase reaction resulting in the conversion of 10-formyltetrahydrofolate to tetrahydrofolate and CO2. Also included in this subfamily is the Arabidosis aldehyde dehydrogenase family 2 members B4 and B7 (EC=1.2.1.3), which are mitochondrial, homotetramers that oxidize acetaldehyde and glycolaldehyde, as well as, the Arabidosis cytosolic, homotetramer ALDH2C4 (EC=1.2.1.3), an enzyme involved in the oxidation of sinapalehyde and coniferaldehyde. Also included is the AldA aldehyde dehydrogenase of Aspergillus nidulans (locus AN0554), the aldehyde dehydrogenase 2 (YMR170c, ALD5, EC=1.2.1.5) of Saccharomyces cerevisiae, and other similar sequences.	0
NZ_CP051487.1|WP_020796911.1|4424847_4426050_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.5809e-95
NZ_CP051487.1|WP_083349367.1|4432330_4433161_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|180446	PRK06180, PRK06180, short chain dehydrogenase; Provisional.	1.05398e-107
NZ_CP051487.1|WP_083349358.1|4423567_4424221_+|response-regulator-transcription-factor	gnl|CDD|226932	COG4566, TtrR, Response regulator [Signal transduction mechanisms].	7.87204e-81
NZ_CP051487.1|WP_168759199.1|4426883_4427867_+|iron-ABC-transporter-permease	gnl|CDD|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	8.98536e-81
NZ_CP051487.1|WP_020796890.1|4437172_4438747_-|purine-cytosine-permease-like-transporter	gnl|CDD|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	2.63024e-53

Protein sequences

>NZ_CP051487.1|WP_020796902.1|4431067_4431472_+|cupin-domain-containing-protein
MRTPMLLALFTLSFTTTATALAAEAPPPDVKEVSVTALPDYPGKEVLMLTVEYPPGGADPVHRHDAHGFIYVLEGSIVMGVKGGKEVTLMPGQSFHEGPNDIHTVGRNASKDKPAKFVVFLLKDQGKPPVLPAD
>NZ_CP051487.1|WP_033045137.1|4430262_4431012_+|SDR-family-oxidoreductase
MKIVVIGGTGLIGTQLCKLLREGGHDVVPATPSTGVNAVTGEGLKAALQGADVVVDVANSPSFEDAAVLEFFEKSGRNLAAAEEAAGVKHHVALSVVGTERMLESGYFRAKMAQEELIKNAGVPYSILRATQFFEFIGAIAQSGAQGDTIRLTSAALQPIASADVAAALAKIAVAAPTGKIEEVAGPDKQPLVSFAKTYLQHTKDQREVITDDNAGYYGAIINDQSLTPGANPILGKIHFDQWLKSTSA
>NZ_CP051487.1|WP_020796904.1|4429665_4430055_-|cytochrome-c-family-protein
MNKAAVMTLVLTLGTGLFATQANAQGDAEAGGKLFKRVCGGCHQIGESARAFFGPQLNGVVGRVAGSTTDYQYSDAMKSSGIVWTREKLAAYIEDPKAVVSGTRMIFWGISDREKIDDLLAYIQTFPAP
>NZ_CP051487.1|WP_168758521.1|4428660_4429545_+|iron(III)-ABC-transporter
MRIVLLFLVSLLAACQTHYVAAPPPAIAPQGRDHADLGLIRELASGRALTPQELVERLAVAPRVLVGEQHDNPDHHALQLWLLRQLAAQRPQGSLLMEMLNPDQQAKVDAAQAATRAGQPPADAYQALSWQANWDWGIYGPLVTYALRQPYPLLSANLDRAQIMQIYKQRPTLSGEASTTQRVQATLLDDIRESHCGLLPEAQMPAMLAVQQQRDRRMAERLLAAPTPALLLAGAFHVRKDLGVPLHLQDLGAGEGNAVLVLAEVGKTVSADSADYVWYTAAQPEQDHCAELRR
>NZ_CP051487.1|WP_168758520.1|4427866_4428634_+|heme-ABC-transporter-ATP-binding-protein
MLRANNLMVRRGNRTVLADIDIELHPGQVLGVLGPNGAGKSTLLAALCDELPANAGTVSLDERALADWPGQERARRLAVLPQSSSLNFAFSVNEVVGMGRLPHASGRVRDAQIVAQALSAADALHLAGRSYLALSGGERQRVHLARVLAQLWPGAEGQTLLLDEPTSMLDPLHQHTILQAVRDFAGRGAAVLVILHDLNLAARYCDQLLLLQEGRPHAYGPPDEVLNAQALEAVYGLQVLIQRHPERGHPLIIAR
>NZ_CP051487.1|WP_168759199.1|4426883_4427867_+|iron-ABC-transporter-permease
MLVFWLSLALGPVSLPLGETLLAGLRLLGLPVEGDDSQQAQLILGQIRLPRSLLGIAVGAVLALSGVAMQGLFRNPLADPGLVGVSGGAALGAAVAIVGGNLLGGLPPAIEPYLLSVCAFAGGLIVTAVVYRFGRSDGQTNVATMLLAGVAMTAMAGAGVGLFTYLADDATLRTLTFWNLGSLNGASYPRLWPLLIVAVGVALWLPRRAAALNALLLGESEARHLGFNVERIKLELVLCTALGVGAAVAAAGLIGFIGLVVPHLMRLLVGPDHRVLLPASLLAGASLLLLADLVARLLLAPAELPIGIVTALIGAPFFLYLLVRGRS
>NZ_CP051487.1|WP_083349361.1|4426102_4426363_+|transmembrane-sensor/regulator-PpyR
MYGFFEHPYRVLTLSHVMLIGGLIALVAGAILAYGLDQYLSLPSLVMAHAMTILGPTAIKLGYVMRLLTLNRLRCQPLSQPPGLAG
>NZ_CP051487.1|WP_020796911.1|4424847_4426050_+|NAD(P)/FAD-dependent-oxidoreductase
MKQQILIIGAGFGGVWSALSAARLLDKHDRNDVEITVLAPQAELRIRPRFYEPDVHTMTAPLHELFDAVGVKFVKGSAEVIDEHNKQVRYTNAAGIQGTLTYDRLVLAAGSKLMRPPVEGMLEHAFDVDEIESATRLEAHIKSLKDKPVSAARNTVVVAGGGFTGIETATEMPARLRAVLGENVDIRVIVVDRAPQVAAALGDGIRPSIVEASQHLGIEWVLNATVAAVDANGVILADGQRIESNTVIWTVGFRANSLTEQVQGTRDHQGRLHVDQHLKVRGHADVYASGDVAYAATDDQGNFAAMSCQHAIALGRYAGNNVAAELLGVEPMAYSQPKYVTCLDLGAWGAVFTEGWEREVKLVKHEAKELKTQINTLWIYPPAADRAVALAAADPLIPVA
>NZ_CP051487.1|WP_033043392.1|4424319_4424694_+|response-regulator
MHNEAMIAVVDNDDSLRMALDTLLRSSGYTVRTYVGPYEYLNSDGPLITSCLICDIQMPEMDGITMYEELATRGMHIPVIFITGNPCAQRPPGSQAMQPIAFFPKPFPIEKLLDCIKTVLERRH
>NZ_CP051487.1|WP_083349358.1|4423567_4424221_+|response-regulator-transcription-factor
MNERQSLNQINHTESMVFIVDDDAPLRESLGSLLRSIGLRVELFGSVADFMQYQRPDTDSCLVLDVRLQGSSGLDFQNELAVAGIKVPIVFITGYGDIAMTVRAMKAGAVDFLTKPFREQDLIDAVCAAHGRDKQRRESERHAEQLQARHQTLTAREQTVMTLATSGLMNKQIAGEIGLSEITVKIHRGQAMRKMGARSFADLVRMAEVLSARPASR
>NZ_CP051487.1|WP_083349367.1|4432330_4433161_-|SDR-family-NAD(P)-dependent-oxidoreductase
MRTWFITGASRGFGTLIAERALRAGDAVIATARKPEEIAARLGDHPNLLAVRLDVTREEQAHQAVAEGIKRFGRIDVLINNAGFGVLGAVEETSASETERLFATNVFGVLNVTRAVLPHMRRQRSGHVINISSIGGYHAYMGWGVYGSTKFAVEGITEALHQELAPLGIHATVVEPGFFRTDFLDEQSLVKTALELSDYDETVGAMRKHAEAANHAQPGDPVKFADAMLALVNAPKPPQRLALGSDTIARIEAKNRFVAQELAQWNELALSTDFKD
>NZ_CP051487.1|WP_168758522.1|4433291_4434197_+|LysR-family-transcriptional-regulator
MKAPSAADLSTFLCVANHLNFSRAAVELGLTPSALSHAVRTLENRLGVRLFNRTTRSVGLTEAGERLFARLKPAFRDIDDALEDLNHYREKPSGNLRITAGRQAAELVLLPLASKFLEAYPDVKLEIVTDDALVDVVAQGFDAGVRFGARLEADMVSLPIGSHMRSVVVGSAEFFRRHPVPQKPEDLHGLPCIRHRFPSGAMYRWEFERGAIAQEIEIDGPLTLGDVSLMVGPALQGVGVAYIFEDMVKAQIADGSLIQVLGDWCPYYPGLHLYYPSRRHVPATLKAFIEFARAAREVAPR
>NZ_CP051487.1|WP_151144103.1|4434529_4434847_+|NIPSNAP-family-protein
MITCYLKYVIDPYQLEAFEHYGKLWIPLVEKFGGQHHGYFLPSEGANNIAMAMFTFPSLAAYESYRQQSMSDPECIAAFKLAEDKKFILNYERSFLRPVFGDRDR
>NZ_CP051487.1|WP_168758523.1|4434848_4435307_-|GNAT-family-N-acetyltransferase
MAILALRADASHIDTIAPLFDAYRGFYGQPSNLPQSRDFIAERIARDESVIFFAEDTVGQALGFVQMFPTFSSIDAHRTWLLGDLFTTPAARGKGVGTLLMNTARDFARLMGAKGMTLETATDNCSAQRLYESLGYVRDPGYFTYCLDLRQD
>NZ_CP051487.1|WP_168759201.1|4435466_4437155_-|choline-dehydrogenase
MTTQKYDYIIIGAGSAGCVLANRLSEDPATSVLVLEFGGSDKSVVIQMPSAFSIPMNTKKYNWRYETEPETYLNGRRIHCPRGKVLGGSSSINGLVYIRGHALDFDEWESLGAQGWGYKNCLPYFKRAESYESGGDSYRGQTGPLHTTNGNHMKNPLYGAWVEAGAEAGYIKTEDCNGYMQEGFGAMHMTVKNGVRCSTANAYLRPAMGRPNLTVITHAMTRQVILEGKRAVGVMYDHGGQTHQVYCNREVLISSGPIGSPHLLQRSGIGPAEVLRKAGIGVRHDLPGVGENLQDHAEVYIQFGCKEPVTLNSKMDPLSKLMIGLRWLLFKDGLGATNHFEAGGFIRSEKGLRWPDIQFHFLPAAMRYDGNKPIKGHGFMVLTGPNKPKSRGYVRVRSADPYEHPEIRFNYLEREEDREGFRRCIRLTREIIGQKAMDRFRDGEIAPGALVTSDEDLDAFVRDNLESTYHPCGSCRMGEDDMAVVDSELRVHGIKGLRVIDSSVFPTEPNGNLNAPTIMLAERASDLVRGVKMLPESDVPVGLVENWENSQRTTLPGRNVRV
>NZ_CP051487.1|WP_020796890.1|4437172_4438747_-|purine-cytosine-permease-like-transporter
MNTNAKSATSVSSLDDKSVVEGHSIDFIPENERTDKLSSQGPFWFLGNFTFFTMTIGFVGPSVGLTALWTTLAGTLGIMFGTLFMAFHGSQGPHLGLPQMIQSRAQFGYRGVILVLLATLFVFAGFNIVNLVLMMQGLHTLFGFSPAVIAVAVTLPAAVLAILGHDWMHRSFKWALCLSLPLYGLVTLAVLMGWVPDAVLPALAEGEAAPAPLGFNWTGFIAQFAAAASYNIAYAPYVSDYSRYLPKNTSSGKLIAVVFLGASLSGAWMISVGGWLADHLHSTDVLVALGQVGNTVSPLMGTAVVVVTILAFLPVIAMNIYSAKLTTLTCVDSIRHIEPTRKARILAIAFVILLQLGVALSIQSSGKGLSVLGIYLVVMLYFLVPWTSVNLTDYFFVRKGRYAIPHFFMPHGNIYGNWGLRGIAAYAIGFISMIPFFYIYDGVEQREVYVGPLAKALGSIDIAWLVGLIVSGLAYYWLSRSIDLAREEAVIQQVEITSPQYTTGDTLTHKQQPRPVFTQTTVGR
>NZ_CP051487.1|WP_168758524.1|4438929_4440441_-|aldehyde-dehydrogenase-family-protein
MDTIVKSYLQKFGVSEATQTFLSKAQKMFIGGTWVDASDGQTSEVIEPSTEGLITRIPMGTTEDLDRAVQAARAQFDGGEWSQAKPAQRERLIQRLADLIEQNADELAQIESIDMGKSVAFAKDVDIQGTVETLRYFAGWATKLHGRTVEPSLPGNYLAYTRKEAVGVVGAIVPWNFPLQTMAWKLGAALATGCTVVVKPAELTSLSALRFAELVQEAGIPDGVINIVTGRGSVVGAAMTTHPGIDKLTFTGSTPVGLTVGRAALDDMKRLTLELGGKSPVIVFADADIPAAAQAVANGVFFNSGQVCDAGTRAYIHSSVHDEFLRELIAYTRTLKMAPGLDPDCFIGPLVSALQKQRVTEYIETGKAEGAELVYGGQPVDGPGFFVEPTIFANCRNDMRIVQEEIFGPVLVTAKFDDDEEALALANDSAFGLAAALYSNDLGKVHRLIPRLKAGSVYVNAHGTLDPSMPFGGYKQSGFGKDLGAEQLDYLLETKAVWITLPG
>NZ_CP051487.1|WP_020796888.1|4440512_4441511_-|agmatinase
MSNNGYESGRLNLPFVGHCTFGKSPVCTDWDALDADVAVLGVPNDMGTQWRSGARFGPRGIREASTLFSFGHAGAYDHEDDVMYLTASDVRMVDVGDADIVHTDMATSNKNTEYAVRKILDAGVMPVVLGGDHSVHAPVIKAFEGRGPIHIIHFDAHLDFVDERHGVRYGHGNPLRRASEMNHIVGMTQMGIRNVSSSNRDDYEAAHEAGSKILSVRDVRRLGVEGVLALIPQNINYYITIDIDGFDPSIAPGTGTPSHGGFLYYEVLEIIQALAKRSKGNIVGMDLVEVAPVYDPTGMTSILAAQLLLNSIGFIFHERGLVRAAAESESLA
>NZ_CP051487.1|WP_020796887.1|4441663_4442578_+|LysR-family-transcriptional-regulator
MIQLHDVDLKLLRVFATIVRCGGFSAAQAALNAGQSTISEQMTHLETRLGVKLCQRGRSGFRLTEQGVAIHEATQRLLSAVENFCMDADVLKQHISGKLNLGIIDTTITDPDSPIPRTTQRFVSRGHDVHLNVYVGTPAELEERVLDGRLHLAIGHFPIHVPGLLQSPLYQEALGLYCGRRHPLYGSTAEGAELLEEIGAGRIVVRGYMQQYDLEHLGVSKAAATVDNIEASAILIISGAYMGFLPEHFAAQWLKSGEMHQLGPASLRLKSPFDVITRRGVAPPPILQAFLEDLAASTRKTANG
>NZ_CP051487.1|WP_151142734.1|4442647_4444156_+|sigma-54-interacting-transcriptional-regulator
MRIHVTFIDRVGITQEVLALLGGRSFNLDAVEMVPPNVYIDAPTLGAEVLEELREALFGVRGVQAVTLVDILPGQRRRLQLDALLAASSDPVLAVDDRGHVLLANPALIALCGREPAGESLSALFDDADLQRTLIAQHFRLPMHEVSLGGHTLLLDAMPITDAGALLTLYQPNRIGERLSALHHDHAEGFDALLGESPPIRSLKARAQRVAALDAPLLIQGETGTGKELVARACHAISGRRDKPFLALNCAALPESLAESELFGYAPGAFTGAQRGGKLGLLELADQGTVFLDEVGEMSPYLQAKLLRFLSDGCFRRVGGDREVKVNVRILSATHRDLEKMVAEGHFREDLFYRLNVLNLQVPPLRERGHDILLMAQHFMQQACAQIQRPVCRLAPSTFPALLGNRWPGNVRQLQNVIFRAAAICENPLVDIDDLDIARTAVERRNDGEVGSLEEAVEGFERNLLEQLYQSYPSSRLLAARLQTSHSAIAIRLRKYGIPNKS

Crispr_ID: NZ_CP051487_10

• CRISPR_ID: NZ_CP051487_10
• CRISPR_location: 4613827-4613927
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP051487_10

Consensus_repeat	Method
GTGACTGATACACCGCGGCGCCTGGTTCGC	CRISPRCasFinder

spacers of NZ_CP051487_10

>10.1|4613857|41|NZ_CP051487|CRISPRCasFinder
CTGTAGGAGCCAGGCTTGCCGGCGAAGAACAATTATGCGGA

CRISPR arrays and Neighbor proteins around NZ_CP051487_10

CRISPR arrays

The CRISPR arrays of NZ_CP051487_10

>merge|NZ_CP051487|10|4613827-4613927|CRISPRCasFinder
GTGACTGATACACCGCGGCGCCTGGTTCGCCTGTAGGAGCCAGGCTTGCCGGCGAAGAACAATTATGCGGAGTGACAGATACACCGCGGCGCCTGGTTCGC

>NZ_CP051487|10|10|4613827-4613927|CRISPRCasFinder
GTGACTGATACACCGCGGCGCCTGGTTCGC	CTGTAGGAGCCAGGCTTGCCGGCGAAGAACAATTATGCGGA
GTGACAGATACACCGCGGCGCCTGGTTCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP051487.1|WP_020801201.1|4605438_4606626_-|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173848
NZ_CP051487.1|WP_020800075.1|4626282_4627368_-|alkene-reductase	unknown	unknown	gnl|CDD|239243
NZ_CP051487.1|WP_033045701.1|4627886_4629215_+|MFS-transporter	unknown	unknown	gnl|CDD|340886
NZ_CP051487.1|WP_168758566.1|4613958_4615194_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225360
NZ_CP051487.1|WP_168758567.1|4619359_4620310_-|acyl-dehydratase	unknown	unknown	gnl|CDD|239534
NZ_CP051487.1|WP_033044538.1|4615340_4617773_-|MMPL-family-transporter	unknown	unknown	gnl|CDD|223964
NZ_CP051487.1|WP_083349409.1|4608482_4609274_+|2-oxopent-4-enoate-hydratase	unknown	unknown	gnl|CDD|132264
NZ_CP051487.1|WP_020801200.1|4604337_4605360_-|ferredoxin--NADP-reductase	unknown	unknown	gnl|CDD|99810
NZ_CP051487.1|WP_168759207.1|4621619_4623254_-|DUF1302-domain-containing-protein	unknown	unknown	gnl|CDD|377751
NZ_CP051487.1|WP_168758563.1|4607635_4608409_+|glucose-1-dehydrogenase	unknown	unknown	gnl|CDD|181131
NZ_CP051487.1|WP_083349410.1|4617787_4618774_-|glycosyl-hydrolase	unknown	unknown	gnl|CDD|226855
NZ_CP051487.1|WP_168758564.1|4609306_4610224_+|acetaldehyde-dehydrogenase-(acetylating)	unknown	unknown	gnl|CDD|236227
NZ_CP051487.1|WP_168758568.1|4623354_4624440_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|214854
NZ_CP051487.1|WP_020800084.1|4612944_4613712_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187589
NZ_CP051487.1|WP_168758565.1|4610234_4611263_+|4-hydroxy-2-oxovalerate-aldolase	unknown	unknown	gnl|CDD|181282
NZ_CP051487.1|WP_168759206.1|4600947_4602555_-|DUF1302-domain-containing-protein	unknown	unknown	gnl|CDD|377751
NZ_CP051487.1|WP_168758569.1|4624432_4626286_-|long-chain-acyl-CoA-synthetase	unknown	unknown	gnl|CDD|236217
NZ_CP051487.1|WP_020800085.1|4612099_4612933_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_CP051487.1|WP_168758562.1|4602689_4604306_-|fatty-acid--CoA-ligase-family-protein	unknown	unknown	gnl|CDD|236072
NZ_CP051487.1|WP_020800079.1|4620314_4621526_-|thiolase-family-protein	unknown	unknown	gnl|CDD|238425

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP051487.1|WP_020801201.1|4605438_4606626_-|acyl-CoA-dehydrogenase	gnl|CDD|173848	cd01159, NcnH, Naphthocyclinone hydroxylase. Naphthocyclinone is an aromatic polyketide and an antibiotic, which is active against Gram-positive bacteria. Polyketides are secondary metabolites, which have important biological functions such as antitumor, immunosupressive or antibiotic activities. NcnH is a hydroxylase involved in the biosynthesis of naphthocyclinone and possibly other polyketides.	6.75401e-119
NZ_CP051487.1|WP_020800075.1|4626282_4627368_-|alkene-reductase	gnl|CDD|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	1.48359e-165
NZ_CP051487.1|WP_033045701.1|4627886_4629215_+|MFS-transporter	gnl|CDD|340886	cd17328, MFS_spinster_like, Protein spinster and spinster homologs of the Major Facilitator Superfamily of transporters. The protein spinster family includes Drosophila protein spinster, its vertebrate homologs, and similar proteins. Humans contain three homologs called protein spinster homologs 1 (SPNS1), 2 (SPNS2), and 3 (SPNS3). Protein spinster and its homologs may be sphingolipid transporters that play central roles in endosomes and/or lysosomes storage. SPNS2 is also called sphingosine 1-phosphate (S1P) transporter and is required for migration of myocardial precursors. S1P is a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. The spinster-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.71733e-77
NZ_CP051487.1|WP_168758566.1|4613958_4615194_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|225360	COG2771, CsgD, DNA-binding HTH domain-containing proteins [Transcription].	5.34451e-11
NZ_CP051487.1|WP_168758567.1|4619359_4620310_-|acyl-dehydratase	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	2.88918e-49
NZ_CP051487.1|WP_033044538.1|4615340_4617773_-|MMPL-family-transporter	gnl|CDD|223964	COG1033, COG1033, Predicted exporters of the RND superfamily [General function prediction only].	3.52392e-79
NZ_CP051487.1|WP_083349409.1|4608482_4609274_+|2-oxopent-4-enoate-hydratase	gnl|CDD|132264	TIGR03220, 2-hydroxypenta-24-dienoate_hydratase, 2-oxopent-4-enoate hydratase. Members of this protein family are 2-oxopent-4-enoate hydratase, which is also called 2-hydroxypent-2,4-dienoate hydratase. It is closely related to another gene found in the same operon, 4-oxalocrotonate decarboxylase, with which it interacts closely.	2.79416e-131
NZ_CP051487.1|WP_020801200.1|4604337_4605360_-|ferredoxin--NADP-reductase	gnl|CDD|99810	cd06214, PA_degradation_oxidoreductase_like, NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like domain with an iron-sulfur binding cluster domain. Ferredoxins catalyze electron transfer between an NAD(P)-binding domain of the alpha/beta class and a discrete (usually N-terminal) domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal portion may contain a flavin prosthetic group, as in flavoenzymes, or use flavin as a substrate. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria and participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.27854e-108
NZ_CP051487.1|WP_168759207.1|4621619_4623254_-|DUF1302-domain-containing-protein	gnl|CDD|377751	pfam06980, DUF1302, Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.	1.90866e-117
NZ_CP051487.1|WP_168758563.1|4607635_4608409_+|glucose-1-dehydrogenase	gnl|CDD|181131	PRK07814, PRK07814, SDR family oxidoreductase.	5.98638e-100
NZ_CP051487.1|WP_083349410.1|4617787_4618774_-|glycosyl-hydrolase	gnl|CDD|226855	COG4447, COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only].	1.13805e-26
NZ_CP051487.1|WP_168758564.1|4609306_4610224_+|acetaldehyde-dehydrogenase-(acetylating)	gnl|CDD|236227	PRK08300, PRK08300, acetaldehyde dehydrogenase; Validated.	0
NZ_CP051487.1|WP_168758568.1|4623354_4624440_-|MBL-fold-metallo-hydrolase	gnl|CDD|214854	smart00849, Lactamase_B, Metallo-beta-lactamase superfamily. Apart from the beta-lactamases a number of other proteins contain this domain. These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.	1.19783e-22
NZ_CP051487.1|WP_020800084.1|4612944_4613712_-|SDR-family-oxidoreductase	gnl|CDD|187589	cd05328, 3alpha_HSD_SDR_c, alpha hydroxysteroid dehydrogenase (3alpha_HSD), classical (c) SDRs. Bacterial 3-alpha_HSD, which catalyzes the NAD-dependent oxidoreduction of hydroxysteroids, is a dimeric member of the classical SDR family. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.07476e-77
NZ_CP051487.1|WP_168758565.1|4610234_4611263_+|4-hydroxy-2-oxovalerate-aldolase	gnl|CDD|181282	PRK08195, PRK08195, 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated.	0
NZ_CP051487.1|WP_168759206.1|4600947_4602555_-|DUF1302-domain-containing-protein	gnl|CDD|377751	pfam06980, DUF1302, Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.	1.66666e-111
NZ_CP051487.1|WP_168758569.1|4624432_4626286_-|long-chain-acyl-CoA-synthetase	gnl|CDD|236217	PRK08279, PRK08279, long-chain-acyl-CoA synthetase; Validated.	0
NZ_CP051487.1|WP_020800085.1|4612099_4612933_-|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.81799e-41
NZ_CP051487.1|WP_168758562.1|4602689_4604306_-|fatty-acid--CoA-ligase-family-protein	gnl|CDD|236072	PRK07656, PRK07656, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP051487.1|WP_020800079.1|4620314_4621526_-|thiolase-family-protein	gnl|CDD|238425	cd00829, SCP-x_thiolase, Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.	1.09647e-97

Protein sequences

>NZ_CP051487.1|WP_020800084.1|4612944_4613712_-|SDR-family-oxidoreductase
MPITAITGSASGIGAAVSAALRAAGHQVIGIDRSNAEVIADLSTAQGRDAAITRVLELSGGVLDGLICCAGVGVTAPTCGLIPAVNYFGVSQLLDGLQGALAKGQQPAALVIGSVAATHSGVDGQAMVEAMIAGDEVQALELANTLGQPHVAYAASKYAISRHARSLAVSWGKRGMRLNVVAPGAVETPLHQASLDDARFGQATRDFVAPLGRSSCPDEIAAVVVFLQSPQASFVHGSVVFVDGGMDAMVRAPHF
>NZ_CP051487.1|WP_020800085.1|4612099_4612933_-|SDR-family-oxidoreductase
MNKVAFITGASRGIGREAALAFARAGFDLAISARTLNEGEQHEHALRDAAGAPLAGSLNGTAQALRDLGCRVLVVPMDLLDSASALGACQAVLAEYGRIDVLINNAIYQGSDLNAGFMDLQAQTLERMFQGYILTPFLLTQAVAEHMVTRGGGVVINVTSGAGESDPPVAAGKGGWGYAYGAGKAAVSRLSGVMATELGDLGVRAYTLNPGVVTTEALKATIGDKGLIALRSGSAPPHVPAAVMLWLATAEQAPGFQRRTIAAQPFALEHGIVADWR
>NZ_CP051487.1|WP_168758565.1|4610234_4611263_+|4-hydroxy-2-oxovalerate-aldolase
MDLRGKSITVHDMCLRDGMHPKRHQISLQQMKDIACGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHTDEEYLSAVIPLMKKAKVSALLLPGIGTVDHLKMAHELGVNTIRVATHCTEADVSEQHISHARSLGMDTVGFLMMAHMNSPEGLVKQGLLMESYGANCIYLTDSAGYLLPHDVSARVTAMRAALKPETEIGFHGHHNLSMGVSNSIAAIAAGANRIDAACAGLGAGAGNTPMEVLVAVCDRMGIDTGVSVFGIQDVAEDLVVPIMDFPIRSDRDALTMGYAGVYGSFLLFAKRAEKKYGVSAREILVEMGRRGMVGGQEDMIEDTAMTLARLRRLG
>NZ_CP051487.1|WP_168758564.1|4609306_4610224_+|acetaldehyde-dehydrogenase-(acetylating)
MSKKIKCALIGPGNIGTDLLYKLMRSEVLEPVWMVGIDATSEGLARARELGLKTTADGVDGLLPHVLEDQIQIAFDATSAYVHAQNSRKLNALGVLMIDLTPAAIGPYCVPPVNLKAQLGLGVMNVNMVTCGGQATIPLVAAVSSVQPVEYAEIIATAASKSVGPGTRKNIDEFTRTTASAVEKVGGAKKGKAIIIINPAEPPLIMRDTVHCLTASEPDQPAITAAIEAMIEQVQRYVPGYKLVNGPVFDGNRVSIFMEVEGLGDYLPKYAGNLDIMTAAAARTAEMFAEEILKGELVLTQTAHA
>NZ_CP051487.1|WP_083349409.1|4608482_4609274_+|2-oxopent-4-enoate-hydratase
MDAHLINALGDELFNALRSRQTLPPLTRRYPQITLEQAYGISLQFLQRREALGEHVIGKKIGVTSRAVQEMLDVHQPDFGFLTNAMQVEDGSDVSLARYNLIQPRAEGEIAFILGEDLQGPGIRAEDVLAASQWVVPCFEIVDSRIDDWQIRIQDTVADNASCGVFALGSQRIDPRSLDLAAVHMQMSKNGQPAGSGLGSAVQGHPCAAVAWLANTLGELGIPFRRGEIILSGALAPLVPVIAGDHISLSMTGLGEASLRFVP
>NZ_CP051487.1|WP_168758563.1|4607635_4608409_+|glucose-1-dehydrogenase
MSILQRFQMDGSVAIVTGSGRGIGRAIALAYAEAGADVVCSARSLDEVQAVAEEVRALGRRALAFACDVNDAEQRQALVRHSVEHMGRITHLVNNVGGGGPNDPLSMTPEQFAQVLNFNVATTYAFCQLCVPLMREAGGGNIINISSVAARYAQRHFSAYGTAKAALSHLTRLLAQDFAPQIRVNAVAPGPTLTEALNGVMPAAMRQVMENNTPLKCLGTPQDIAAAALYLASPASAWVTGKIIDVDGGADSSVWPG
>NZ_CP051487.1|WP_020801201.1|4605438_4606626_-|acyl-CoA-dehydrogenase
MHSMREKTQDERDLLERARSLVPALKARTAQADKDLKVPVESVVELQSAGLLRALQPKAFGGYEVDPRTFFEIQTILAEGCMSTAWIYGVMGVHPWQLARYPIEAQREVWADDHSALICSTYMPAAKVTVVEGGYRISGRWGFSSGSEHCQWVFLGGILPPDGEMAAEHGTFLLPRHDYQIEHNWDVMGLRGTGSHDIVVEDVFVPAHRVQRTNNWTLEATPGRLVNTNPIYAIPFAQVFSRAVSTSAIGALQGAINEFRDNAAKHIGKHGARTAEDPVAQTAVAEAMVTVDSLRLVLERNYEHLMTLARAGEYPDTETRLLYRYQSAYVTNICAERANDLLRSMAASGLYNTNPVARLFRDLHQARGHIANNYMAYGRSYGAVMLGLPNPDPYV
>NZ_CP051487.1|WP_020801200.1|4604337_4605360_-|ferredoxin--NADP-reductase
MNNYLALRVARVIEETADARSLVFDVPEHLSERFRYQPGQFLTLRVPFEDGWLPRCYSLSSTPLLDEPLRVTVKRVHEGRASNWLCGELQAGQNLEVLPPAGVFVPRSLDGDLLLFGGGSGVTPVLSILRSALLAGTGRVLLIYANRDESSVIFKDELRSLASAHPQRLQIVHWLDSVQGIPSVGQLAELARSFIDAQAFICGPGPFMDAAVSALKTLGMPDRRVHVERFVSLPGEGELPQVTSSEAAVAAQLAVRLDGEDHQLACDSGETVLAAMERAGLNPPSACRVGGCASCMCTLESGEVELLHNDALDAGDLAEGWILACQAVPTSAQLRIRFPD
>NZ_CP051487.1|WP_168758562.1|4602689_4604306_-|fatty-acid--CoA-ligase-family-protein
MNQSLNLAAPLSAAPATLAQLVFSSAERFAGRTAIEEHGQCIDYADLPDRVMGFARGLMALGIQAGDRVGVWAPNSGDWILAALGIQCAGAVLVPINTRMKGLEAADVLERSGCRVLFVQQRFLDVDYPALLAPRRPASLEHLVIIDGDTPEQPSDLTLAQFLQGAATIDAGSAKRRAMAVGPEAMCDLLFTSGTTGKPKGVMSGHGQNLRAFTEYVRVLGLVPEDRYLIVNPFFHAFGYKAGWLTCLIGGATILPHAVFDAEQVFQRIARERISVLPGAPTLYLSLLAHPQLKQTDLSSLRIAVTGSASIPPSLIERMRNELGFAVVTTAYGLTECGGLATICDPQDSAQVIAGTSGRPIAGTEVSIRDPHNQALEAGQTGEICLRGFHIMQGYFQNPEATREAIDAEGWLHTGDVGRLDGAGNLIITDRLKDMFIVGGFNCYPAEIEAALIRHPAIAQVAVIGVADERMGEVGCACVVLREGRELDEAQLIAWSREQMANYKVPRQVRFLNALPLNPSSKVAKNELRALVANSAQA
>NZ_CP051487.1|WP_168759206.1|4600947_4602555_-|DUF1302-domain-containing-protein
MSVGRCLLATAITIASATASAAPSIELGENTTLDSSLTVNYTASMRTAKQASQYLNDPNNDDGTRNFKRGSLINNRLSLFGELQLKHDNLGAVLRGSQFYDDVYNQKNANDSPQTVNKTGHNDGFSDETRRLSGSMARLLDAYVYGNFELGETQYLSLKAGRHLVAWGESLFWPNISQGQAPVDATKFNVPGTEAKDSYLPVGQVSGSWSLNEDLALVGYYQYEWEKTQLNPVGDYFGSDTFGPGAEFYRLGSGVVNSLPNGLAVGYAGEKDASDSGQWGLGVRYRITENTEVGLFHYRYNERIGSMFFDFTGTTQYSSLKGIGHDGTAPSYRLGYFEDVKLTGVSFSSKVGDSVQYAGDLSYRDGASVYLNNGAPTTGQIWQGNLNAMYILGPSLLAQQTTFMGEVVHQHIDGVDSLTITGGGAGVDGTFDQFESKTQTRGSTLFGVGAYMDYPSIATGLDLSTKVVWTQNVDGSAYQGLGRDEKRLTVGGDFKYLGNFQIGMTYVAYLSSPDVAQGRLLADRDYLSLNAKYTF
>NZ_CP051487.1|WP_168758566.1|4613958_4615194_-|helix-turn-helix-transcriptional-regulator
MQNGDLTHEALASLGLDLTRYNQLVGEIYEGALDPKLMATALRSFLKLYDANFVTLILRVPDQPDTGVMIIVGEIEGAGDVCYMTYPQTNSPFANQPLDHVFTVDDIMSTTQWEQNGYFKMFCEPHDVYHLMCADISTPDGGKLRFRMTRPKRAANFSAHERAVCASFLPHLRRASQLHNLLDRSESLSELYSQAISRLSVATLVLDESGSVLQINPVAQEILARSDGLKLVGGRLEATYPSDNRELQRLIRAAFSPDAPKDAEAMSVTRPSGLVALGVVVESIRSLDWAEEKGQPAALVYIRDASSKSLASEVVTKQLFNLTKAETALAMELANGLSLEEAAEVLNIRRNTARAHLRSIFSKTGVRRQTELVRILLNSVVALGKPRLGLKVTEKIKVPPLQLAVPIYRQA
>NZ_CP051487.1|WP_033044538.1|4615340_4617773_-|MMPL-family-transporter
MNQGKHWVTRGVETCADYLMAWRKGLLLLFVLVTLGLGYSATHTQLDPGFNKQIPVRHEYMVNFLKFSRYFTGANRFLVSVRWKGEGDIYNAEYLETLRKVTDDVFFISGVSRPSVTSLFTANVRYIEITEEGFFGDVVVPPRFSGTPEDLAQVRSNTAASGQVGRLVANDLKSAMVRADLQDTDPKTGQPVSYVEIAKRLEEVRGKYNSPDIEINIVGFAKLVGDVVEGLNTVIGFFVVAFVITGLLLWLYSRSLRLTVVALLVALLPVVWLLGLLPLLGLGIDPMSILVPFLIFSIGVSHAVQMTNAWKQDVLAGSSSREAARLAFCKIFIPGSLALLMNALGFAVIMMIDIPIVHELGVTACIGVMLMIITNKLMLPVIISYLRLEPALLRRAQARPAGRHRLWWRLSALAEPGPALGVFAVSLLLLAAGAWKARDLAVGDIGAGAPELRADSRYNQDNAKIINSYSIGLDVLSVFVQVKGVDEGCLSPTVMRAVEAFDFRMRTVTSVQSIQSVADMGKRVIAGNNEGNPRWAAIPGSPRGLSQGARAYMPDDGLVTDGCQQMQILVFLANHEGSTVSHVISEANRIIAEVSSPEVEFLLAGGNVGVMAASNEAVKRAEVIMLGALFGSVALFCWLTFLSIRAVLCILVPLAIVAILCNALMTLLGIGLKVATLPVMALGVGVGVDYGIYLYERIQHEMLRGANLREAFYEAMCQRGTAAVFTAVTMAIGVCTWAFAPLKFQADMGVLLSFMFLVNVLGAIFLLPALAAWFNRGRPLVTARVRQPVPAHGQFRLKNSPAARDTANEK
>NZ_CP051487.1|WP_083349410.1|4617787_4618774_-|glycosyl-hydrolase
MRSVIGYLVCLVVALTIGYTFSPKSPPQAELLATRPDRVQINGLLNLGSRVVAVGERGSILLSDDQGVSWQPASVAPQRDATLTALVALDPQRLLAVGHDGLILRSTDAGSHWQEIRYDSDLGEPLLGIWSSGGDNVMAFGSFGKFYQSSDAGQTWTPQVLDIDSAHLNSMAGGDDGRRMLVGEQGLVLRTADGGQHWQTLPAFYSGSLFGIVRLSANNWVTYGMRGHVFVSHDFGDSWTQIDVGNQLPLYGHVLLPDHSGLVIVGAGSSVVRLDAQGALVGVARLAGLGTLTSAAMVGSRLLVGGERGVLQGSGGSVAALVATQATQ
>NZ_CP051487.1|WP_168758567.1|4619359_4620310_-|acyl-dehydratase
MSNNKPMPVATQISAPFWEGLKARRLLIQQCNACTHWNFYPRRHCPVCLEHDLAWREVDGAATLYSYTVTRIATLPDFMDEMPQKLAVVELAQGVRINTNLVGLEEDEIRIGMALQPVFAEVDAKGNRLLRFTGVDKDAASLEPLPAQDSEPAPVASEQPPVRQIDLNDEAALQALVSDQFSDWSNVVVVDQALIDAFAQLSGDDYWIHTDPERARLQSPFGGTIAHGALVQVLQSRMKLALGFEISGFTTQVNYGSDRLRFPAPVPAGSRIHSRARVKKVDLSARGTQLTLELTTHVVGQDRPSVINDLVILYLA
>NZ_CP051487.1|WP_020800079.1|4620314_4621526_-|thiolase-family-protein
MGLKGHAAIVGSAQYKPEKYSTAPKMFHLEQVADLAAQALRDAGLKASDLDGLVINGPHFHEASVFVPAMAAEYLGLRLNFAEVVDLGGCTSVGMVWRAAAAIELGLCQAVLCVIPARMAPLGPDEDPGWMARSMRFGGHSTAFGAPEAEFDLPYGHMGQNTGYAMIAQRYAAQYDYDQRAMAKIAVDQRTNALANPQAMFYGQPLTIEQVLASKMVADPLHVLEIVMPVAGGAALIITNKEVAARARKRPAFITGFGEHLAFKSPSYAEDMLRTPIGPASERAFAMAGLKPKDVDAAQIYDCYTITTLLTLEDAGFCGKGEGMAFVREHDLTWRGDFPMNTHGGQLSFGQSASAGGMSQVIEAVTQIAGTAGERQLGRCDSVYVSGTGGVMSEQGALILQGA
>NZ_CP051487.1|WP_168759207.1|4621619_4623254_-|DUF1302-domain-containing-protein
MVSSAFQVSSLAAAIALVTTPVWAGDTIEFDNGLTMDWSVTTSYGIGVRTGSQSDRLLTVNADDANRNFDSGSLTTNRVGALGEIILRKDNYGAVVRGSTFYDDVYHSGNDNDSPATVNKTGSNDEFTSDTRYYSGGRSKLLDAYVFSGWRFDNDTMLDVKAGRHIESWGESLFYPGVNGVQNPSDAVKASQPGVEVKEILLPVGQFSGSFRLNPQLTFGAYVQYEWKGTELPPVGSYLSSSDVVGPGREFIYANGQKIAYRGTDEPRDSGQWGVQVRYRPVPAIELSLFHVNYHDKNPATALVGYDPRPVGGGLNAFVSNGYRIKYFEDIKLTGIAASTKIGDTQFGAEWSYRDGAPVMVNTGLGAVPSKGKGQQMQLSALRILGNRPWASQTTLTAEIIRVQVDSVESTSAAPNLQGVNLLPSLAPLVASSDDYTYSTAAGYRTKSSSAYTVGASFSYPGVFQGWDLEVPFSFSNVFSGSTPMAGSISGVAGDRRLSAGTTFKYLGNLELGLRYISYLGAADPIDRPFADRDYATFSMKYTF
>NZ_CP051487.1|WP_168758568.1|4623354_4624440_-|MBL-fold-metallo-hydrolase
MADLDDNGHELRGGLRYPWPQAPDRGQVREVAPGVWWLRMPLPFRLDHINLYLLRHTDGWVAVDTGMNTDQTREVWERVFSEVCDGLPLLAVVCTHFHSDHAGVAAWLSERFQCPVYMTASEFQALHLKFPAGQPPGWDFLDFYRKAGVADEQSTEMFAVMSNAHFLPAPLNHYRRLREGSLLNIGGRTWQVVIGRGHSPEHACLYAADDGLLISGDQVLPRITSTVGVHATEPLANPLGDWLDSIEHLRSVPDSVLVLPAHERPFFNLHERLDQLDAHHRGHLAQMLANCDEPRTVLELMAVLFPRLSGRFDELMALGETLAHANYLVAEGSLAREEDRGCFRYRRAVRGACPVTPLNVF
>NZ_CP051487.1|WP_168758569.1|4624432_4626286_-|long-chain-acyl-CoA-synthetase
MNLNDLTGVLPTHPVPREQTQALLDQRSAAAGLIKPSDRYTLADRLEHQAREQGDRPFLIYNEQTLSYLEVDARANQMAHTFYANGLRAGDVCALAMENRPSFFCTWFGLVKLGVVVAFINTQVNGRPLLHALQTTDAKALVIGEECLANIQATEGFPDLPCWLIRDAENSWSGPLPKGVDGHFDARLEKAPRTPFPRDIRAHIEAQAATLLIFTSGTTGLPKAARYSHMRWMSSGDVMEVTLQATREDVFYCCLPLYHGAAATSVTSTALRAGAAIVVRRKFSVREFWNDVARHQISIFQYIGEICRYLLNQPVRAGEREHSLRCMLGAGLSPDSWQRWLERFGPIQVFEGWGATEANAAVINVDNYFGSCGRVPDWNKTNVRLVRYDIENDCHPRDENGFYQLCEVGEVGEAMGFIVDHPEIGGGRFEGYTSAEATESKIRRNVFREGDAYWSSGDLLREDANGYCYFVDRIGDTYRWKSENVSTLEVAGALGDLAGLELINIYGVQVPGHEGRAGMAAVLMQAGQAFDPDALYALTEARLPRYAAPVFIRVTQSADLTASFKLRKVDLQRQGYCPSLCSDPLFIRDDQARTYVPYSVEALTRAGLTPFSVANHG
>NZ_CP051487.1|WP_020800075.1|4626282_4627368_-|alkene-reductase
MSVLFEPVALGELQLANRIVMAPMTRSRALADAVPGSAMVEYYRQRASAGLIVAEGTAPSASGLGYCRTPAIYTGEQIAGWQQVTEAVHAEGGRIVLQLMHVGRAASRHNKPTWAATVAPSALRARTQVFSDAAGLVDTDEPQALTLQGIGDVIEDYRQAALNARQAGFDGVELHCTSGYLPMQFMASGSNQRSDAYGGDAKGRVRFAKEVIEAMATAIGAGRVGFRLCPGNPYNDIDDRDPAETAAALCEAVAPLGLAYLHIMRSPLADLDAFALARRHSPHALILNDGFDGLSASAALASGEGAAVSFGRHFIANPDLVERLKRGLPLSGFDRKTLYTPGPAGYSDYSAYQAIAQEVAQ
>NZ_CP051487.1|WP_033045701.1|4627886_4629215_+|MFS-transporter
MNQSTPVTWRTHYALFVLASIYVFNYIDRQLMAILIEPVKLEFGISDTGIGLLSGVTFAVFYTVFGFPLGRLSDRIGRKPVIAFSCIAWSLMTMLCGMAGNFLTLVLARIGVAVGEAGGTAPSVAMVSDLYPANRRSTALSVLMLGSSLGAIVGLGLGGWIAQHHGWRYAFLLIGAPGIFLGLLLLLTVRTPKRVVPQAHLAMQQDGWLKTLVELFRMPSFLCLVLTGGAAAIAGYAIGTWSPSFLIRSHGLNLQEAGFLVGVVGGTGATFGTLLCGMVTDRMARRDVGWQIGVPLLGTLISIPFALAYFLWPQGTAFHIGNIAVPQAFLFYSAFAFFGVWWATPCLSAITHLFPATRLAQATAIFVMSMTLLGVGIGPLFVGMLSDFFVPTLGSESLRYALASSVSMLMLASVFLAFALPRYRQQMKSPAAHLAPVRAVTA

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP051487_5	5.1|2783352|54|NZ_CP051487|CRISPRCasFinder	2783352-2783405	54	NZ_CP051487.1	2374743-2374796	1	0.981
NZ_CP051487_6	6.1|3053779|31|NZ_CP051487|CRISPRCasFinder	3053779-3053809	31	NZ_CP051487.1	2893676-2893706	1	0.968
NZ_CP051487_5	5.1|2783352|54|NZ_CP051487|CRISPRCasFinder	2783352-2783405	54	NZ_CP051487.1	3553188-3553241	2	0.963

1. spacer 5.1|2783352|54|NZ_CP051487|CRISPRCasFinder matches to position: 2374743-2374796, mismatch: 1, identity: 0.981

ggcaagcctggctcctacagtaaaagcgaaaacctaagtggccgttaccgcagc	CRISPR spacer
ggcaagcctggctcctacagtaaaagcgaaaccctaagtggccgttaccgcagc	Protospacer
******************************* **********************

2. spacer 6.1|3053779|31|NZ_CP051487|CRISPRCasFinder matches to position: 2893676-2893706, mismatch: 1, identity: 0.968

cccggttcgccggcaagcctggctcctacag	CRISPR spacer
cctggttcgccggcaagcctggctcctacag	Protospacer
**.****************************

3. spacer 5.1|2783352|54|NZ_CP051487|CRISPRCasFinder matches to position: 3553188-3553241, mismatch: 2, identity: 0.963

ggcaagcctggctcctacagtaaaagcgaaaacctaagtggccgttaccgcagc	CRISPR spacer
ggcaagcctggctcctacagtaaaagcgaaaccctaagcggccgttaccgcagc	Protospacer
******************************* ******.***************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP051487_2	2.1|2266892|31|NZ_CP051487|CRISPRCasFinder	2266892-2266922	31	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	57005-57035	7	0.774
NZ_CP051487_2	2.1|2266892|31|NZ_CP051487|CRISPRCasFinder	2266892-2266922	31	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	138684-138714	7	0.774
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	766552-766582	7	0.774
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP054032	Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence	436330-436360	7	0.774
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP015322	Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence	255825-255855	7	0.774
NZ_CP051487_6	6.1|3053779|31|NZ_CP051487|CRISPRCasFinder	3053779-3053809	31	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	213569-213599	7	0.774
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP042496	Leclercia adecarboxylata strain E61 plasmid pE61_003, complete sequence	44055-44085	8	0.742
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_MH909330	Leclercia adecarboxylata strain 150707804 plasmid p707804-1FII, complete sequence	79919-79949	8	0.742
NZ_CP051487_6	6.1|3053779|31|NZ_CP051487|CRISPRCasFinder	3053779-3053809	31	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	1454950-1454980	8	0.742
NZ_CP051487_6	6.1|3053779|31|NZ_CP051487|CRISPRCasFinder	3053779-3053809	31	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	240505-240535	8	0.742
NZ_CP051487_8	8.1|4117000|33|NZ_CP051487|CRISPRCasFinder	4117000-4117032	33	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	199724-199756	8	0.758
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP033036	Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence	333653-333683	9	0.71
NZ_CP051487_2	2.2|2266946|31|NZ_CP051487|CRISPRCasFinder	2266946-2266976	31	NZ_CP033024	Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence	264154-264184	9	0.71
NZ_CP051487_6	6.1|3053779|31|NZ_CP051487|CRISPRCasFinder	3053779-3053809	31	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	2063860-2063890	9	0.71

1. spacer 2.1|2266892|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 7, identity: 0.774

cgccggtatcgaccagttgttgggcggcact	CRISPR spacer
tgttggcctcgaccagctgtttggcggcact	Protospacer
.*..**. ********.**** *********

2. spacer 2.1|2266892|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 7, identity: 0.774

cgccggtatcgaccagttgttgggcggcact	CRISPR spacer
tgttggcctcgaccagctgtttggcggcact	Protospacer
.*..**. ********.**** *********

3. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 7, identity: 0.774

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
tgccgacaatgacgtcatcgatggcgaaggt	Protospacer
.* ************* **.*******.*..

4. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP054032 (Rhizobium sp. JKLM13E plasmid pPR13E01, complete sequence) position: , mismatch: 7, identity: 0.774

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
tgccgacaatgacgtcatcgatggcgaaggt	Protospacer
.* ************* **.*******.*..

5. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP015322 (Mesorhizobium amorphae CCNWGS0123 plasmid pM0123d, complete sequence) position: , mismatch: 7, identity: 0.774

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
ccccttcgatgacttcctcaatggcgatgac	Protospacer
*  *  *.***** ************* ***

6. spacer 6.1|3053779|31|NZ_CP051487|CRISPRCasFinder matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 7, identity: 0.774

cccggttcgccggcaagcctggctcctacag	CRISPR spacer
acgaattcgcgggcaagcccggctcctacgg	Protospacer
 * ..***** ********.*********.*

7. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP042496 (Leclercia adecarboxylata strain E61 plasmid pE61_003, complete sequence) position: , mismatch: 8, identity: 0.742

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
cggtattcatgacgtcttcaatggcgaagac	Protospacer
**... . ********.**********.***

8. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_MH909330 (Leclercia adecarboxylata strain 150707804 plasmid p707804-1FII, complete sequence) position: , mismatch: 8, identity: 0.742

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
cggtattcatgacgtcttcaatggcgaagac	Protospacer
**... . ********.**********.***

9. spacer 6.1|3053779|31|NZ_CP051487|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.742

cccggttcgccggcaagcctggctcctacag	CRISPR spacer
ccccgttcggcggcaagcctggcgacaagcc	Protospacer
*** ***** *************  * *   

10. spacer 6.1|3053779|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 8, identity: 0.742

cccggttcgccggcaagcctggctcctacag	CRISPR spacer
ccccgttcggcggcaagcctggcgacaagcc	Protospacer
*** ***** *************  * *   

11. spacer 8.1|4117000|33|NZ_CP051487|CRISPRCasFinder matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 8, identity: 0.758

actggttggctgcaaggccgccttcgctggcag	CRISPR spacer
gctcatgggcggcaaggccgccttggctggcga	Protospacer
.** .* *** ************* ******..

12. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP033036 (Agrobacterium fabrum strain 12D13 plasmid pAt12D13a, complete sequence) position: , mismatch: 9, identity: 0.71

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
cgacgccaatgacgtcctcgatgagttaacc	Protospacer
***** *************.***.   .. *

13. spacer 2.2|2266946|31|NZ_CP051487|CRISPRCasFinder matches to NZ_CP033024 (Agrobacterium fabrum strain 1D132 plasmid pAt1D132a, complete sequence) position: , mismatch: 9, identity: 0.71

cgacgacaatgacgtcctcaatggcgaggac	CRISPR spacer
cgacgccaatgacgtcctcgatgagttaacc	Protospacer
***** *************.***.   .. *

14. spacer 6.1|3053779|31|NZ_CP051487|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 9, identity: 0.71

cccggttcgccggcaagcctggctcctacag	CRISPR spacer
cccggttcggcggcaagccttgccttgaata	Protospacer
********* ********** **... *  .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1367561 : 1377072	9	Pseudomonas_phage(50.0%)	NA	NA
DBSCAN-SWA_2	2486844 : 2587244	133	Pseudomonas_phage(32.5%)	plate,terminase,tRNA,integrase,transposase,holin,tail,portal,head	attL 2494254:2494303|attR 2589507:2589556
DBSCAN-SWA_3	2991139 : 3032300	37	Bacillus_phage(50.0%)	holin,coat	NA
DBSCAN-SWA_4	4462729 : 4469005	8	uncultured_Caudovirales_phage(83.33%)	tRNA	NA
DBSCAN-SWA_5	6348138 : 6390952	39	Tupanvirus(33.33%)	transposase,holin,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP051487|1367561:1377072|DBSCAN-SWA
GGTGAGTCTCACAGTCATAGCGCAGCGTATGGGTACAACGAGCTTTCAGCGCCTGGTGACTGGCCTTGTCATGAGCACCCTGCTGGTCGGTTGCTCCAGTAACAAATCCAGCGACGTACGCGTTGTCGACCGCAACAATGCCGCCGCCCAGCGTCCGGCCGTGACCACCGGGCAATACGTCGTTCGCCCCAAGGACACGCTGTTTTCCATCGCCTTTCGCTACGGCTGGGATTACAAGGCACTGGCGGCGCGCAATAACATAGCGCCGCCGTACACCATCCATCCGGGTCAGACGATTCGCTTCGATGGACGCAGCGGTTCAACGCCGACAACGGTGGTCAGCTCCTCCAGTTCTTCGCCTTCATCGTCAAGTAAGACCACGGTCATCCGTCGCTCTGCAGACGGTACGACCACGACGACACCGGTGGTTGTACCGTCCGTCGCGAACAAGCCGGCACCCACTCCACTGCCTCCACCGGGTCCAGCCCCGACCGGCTGGGGGTGGCCATCTAATGGCATTTTAATCGGCAAATTCTCCTCAAACGGTAGTTTGAATAAAGGAATTGATATCGCAGGGGATTTGGGACAGCCTGTTTTAGCTGCGTCTGATGGGACGGTGGTATACGCCGGGAGTGGCTTAAGGGGCTACGGCGAATTAGTCATCATCAAGCACAGTGAAACCTACGTCAGTGCCTACGGACATAACCGCAGGCTGTTGGTTCGGGAGGGGCAGCAGGTCAAGGTCGGACAGACAATTGCCGAAATGGGGTCAACGGGTACAGACCGGGTGAAACTGCATTTTGAGATTCGCCGCCAAGGTAAACCTGTAGATCCGCTGCAATTCCTGCCGCGTCGTTGATCGCTTTCCAGCCTGTTCCGTCACGTAGAGGGGACAGGCTCCAGCGTTGCCAGGGATAAAGGCGCCGCTTGAGCTTGAGGTCGAACTCACCAAAGGACTATAACAATGGCTCTCAGTAAAGAAGTGCCGGAGTTTGACATCGACGATGAGGTTCTCCTGATGGAGGCCGACGTCGGCACGGATTCGATGTCGAATGATGAAGGGGCGGCTCCACCTTCCGTTCGTGCCAAATCCAAACACTCCGCGACATTGAAGCAACACAAGTACATCGATTACACGCGGGCACTCGATGCCACGCAGCTGTACCTCAATGAAATCGGCTTTTCCCCTCTACTGTCCCCCGAAGAAGAAGTGCATTTTGCGCGCCTGTCGCAAAGTGGTGATCCGGCCGGGCGCAAACGCATGATCGAAAGTAACCTGCGCCTGGTGGTGAAAATCGCCCGACGTTACGTCAATCGGGGCCTTTCGCTGCTCGATCTGATCGAAGAGGGCAACCTCGGATTGATCAGGGCGGTGGAGAAATTCGACCCTGAGCGCGGCTTCCGCTTCTCAACCTACGCAACCTGGTGGATTCGTCAGACCATCGAGCGCGCAATCATGAATCAGACCCGGACCATCCGGTTGCCGATCCATGTGGTCAAGGAGCTCAACGTGTACCTGCGGGCCGCACGGGAGTTGACGCAAAAACTCGATCATGAACCCTCACCCGAGGAGATCGCCAACCTGCTGGAAAAACCGGTAGCGGAGGTCAAGCGCATGCTGGGCCTCAACGAGCGGGTTTCTTCGGTCGACGTCTCGCTGGGTCCGGATTCGGATAAGACCCTGCTGGACACCCTTACCGACGATCGCCCAACCGATCCATGCGAGCTACTGCAGGATGACGACCTGTCTCAAAGCATCGACCAATGGCTCTCGGAGTTGACCGACAAGCAGCGCGAGGTGGTTGTACGCCGCTTCGGCCTGCGCGGTCACGAGAGCAGCACCCTTGAAGATGTGGGCCTGGAAATTGGCCTGACCCGGGAGCGGGTTAGACAGATTCAGGTAGAAGGCCTGAAGCGTCTGCGGGAGATCCTGGAGAAAAACGGGCTATCGAGCGAGTCGCTATTTCAATAAGCCATTCGTTTGCTGGATAACAAGAAGCCCCGACTGGTTCGGGGCTTTTTGTTATCTGCAATTCTGGTTTTGATCTCGGGGACGCCAGCGCGGCTTTGTAGCTTCAGGGTGTAAGTCTTCGCTTACTCTTTGCGTAAGTGTTCACTATTTTTACAGGTTGGCAGTCGACCATATTTTTCGCAGGTCTTTTTTATCCGACTGATAAACAAGCAGATTTTCTAACATGAACGGGATGTGACAAGCCATCAGGGCCTGATCGGACGATTGCTCTTGGCGGTAAAAACTCTAGTATCGGTGTTGTGTCAACGGATAGACACGCCCTTCAAGGATGAGGGGAAAGGACATCGCAGGAAGCGATTCATCAGGATGATGAAAAGGAACACAGGGAATAGGGAAAAAATGTGGGCGGGTCATACCGCCCCTTTTTTTTGCCTGCACCTGTAGGAGCTGCCGAAGGCTGCGATCTTTTGATCTTAAAAAAAAGGCCCTTGTGGGGCCTTTTTCAGGAACGCGGGGATAATCAGCGTTCGAGGTGTTCGATCTTGCCTGGCTTGCCATCCCACTCAGCGGCATCGGGCAACGGATCTTTGCGTTCGGTAACGTTCGGCCAGATCTCAGCCAATTCGAGGTTCAGCTCGATAAAGTTTTCCATGCCTGCAGGCACCTCATCTTCGGAGAAGATGGCCACGGCAGGGCATTCAGGTTCGCACAGTGCGCAGTCGATGCACTCATCCGGGTGAATCACCAGGAAATTCGGGCCTTCGTAAAAGCAGTCCACCGGACAGACTTCTACGCAGTCGGTGTACTTGCACTTGATGCAGTTGTCGGTGACGACGAAGGTCATTTCTAATTTTCTCCTCAGGCGCGGCTTGCAGCGCCCCTTCACGTAGGGGTCGCAAGGTTTGGGAGCGATAGTCTGCAAGCCAGGCTAATAGCCCGCAGCATCCCAAACCGCGCGAGATTCTAACAGCTTGCAAGCCTGTGCGTTAGACCCGTGTCTTTAGTGTATAGAGCATTTCGAGTGCGCGACGTGGCGTCATGTTGTCCAGATCAAGTTTGGCCAGTTCATCCAGCACCGGATGTGGCAAGCTCGCGAACATGTCGCTCTGCTGCGGCGTGGCCGGTTTGCCTTTGGCTGGCGCAGGCGCCTCATGGGGCAGGGCGGTGTCTTCCAGCCGGCTCAAGTGCTCACGGGCGCGTACGATCACTTCGTTCGGAACACCAGCCAACTGCGCGACTGCCAGGCCATAGCTCTGGCTGGCCGGCCCTGGCAGTACATGGTGCAGGAACACGATGCGTTCGTTGTGCTCGGTGGCATTGAGGTGCACGTTGGCCACCAATGGCTGGGCTTCCGGCAGTACCGTCAGCTCAAAGTAGTGGGTGGCGAACAACGTGTAGGCCCGCAGGTGTGCCAGGCGTTCCGCCGCCGCCCACGCCAGGGACAGGCCGTCGAAGGTGCTGGTGCCGCGCCCGACTTCGTCCATCAGCACCAGGCTGCGTTCGGTGGCGTTGTGCAGGATGTTGGCGGTTTCGCTCATCTCGACCATGAAGGTCGAGCGCCCGCCGGCCAGGTCATCGCTGGAGCCGATTCGGGTGAAGATGCGGTCGACCAGGGACAATTCACAACTGGCCGCCGGCACGAAGCTGCCGATGTGTGCCAGGAGTACAATCAAGGCGGTCTGGCGCATGTAGGTGGACTTACCGCCCATGTTCGGACCGGTGATCACCAGCATGCGGGTGTTGTCGTCGAGACTCAGGTCGTTGGCCACGAAAGGCGTGGTCAATACTTGTTCAACCACAGGGTGACGACCCTGGGTGATCCGCATGCACGGCTCGCTGACAAAACGCGGGCAGTTCAGGTCGAGGTTCAGCGCCCGTTCGGCCAGGTTACTCAGTACGTCGAGCTCGGCCAGCGCTGCAGCAGTGTCCTGCAAGGGTGGCAGTTGGGCGATCAGGTCTTCGAGCAGCGCTTCGTACAGCATCTTCTCACGTGCCAGGGCACGGCTCTTGGCAGAAAGAGCCTTGTCTTCGAAGGCCTTCAGTTCCGGCGTAATGAAGCGCTCGGCGCCTTTGAGGGTCTGGCGGCGAATGTAGTCGGCGGGTGCGGATTCAGCCTGCTTGCTCGGCAGTTCGATGAAGTAGCCGTGGATGCGGTTGTAGCCGACTTTCAGGTGAGACAGGCCGGTGCGGGCTTTTTCGCGGGCTTCGAGGTCGATCAGGAATTGCCCGGCGTTTTCGCTGAGTGATTGCAGTTCATCGAGTTCGCTGTCGTAACCGGTTTTCAACACCCCGCCGTCACGGATCACCGCGGGCGGGTTGTCGATGATGGCTTTTTCCAGCAAGGCCGCCAGCTCCGGGTAGGTGCTGGTAGTGTCTGCCAGTTGGTTGAGGTGCGGCGCTTCAAGTTCGGTCATTGCCGCTTGCAGTTGCGGCAGCGCGCCGAGGGCATCGCGCAGGCGCGCGAGGTCGCGCGGACGGGCATTGCGCAGGCCGATCCGGGCGAGAATGCGCTCGATGTCGCCGATTTCCTTGAGCTGCGGCTGCAGCTTTTCGAAACGGTAGCCGTCCAGCAGGCAGGTGATCGAGGTCTGCCGCGCCAGCAACACGTTCAGGTCACGCAGCGGGCGGTTCAGCCAGCGAGTCAGCAGGCGGCTGCCCATGGCGGTCTGGCAACGATCGACCACCGACTGCAGGGTGTTGTCACGACCGCCGGCCAGGTTGGTGTCCAGTTCCAGGTTGCGGCGACTCGCCCCATCCAGCACCACGGTATCGTCCAGGCGTTCGTGGCGCAGGCTGCGCAAGTGCGGCAGGGCGGTGCGCTGGGTTTCTTTCGCGTAGGCCAGCAGGCAACCGGCGGCGCCGATGGCCAGGGTCAGGTTTTCACAACCGAAACCCTTGAGGTCCTGGGTCGAGAATTGCTGGCAAAGACTCTTGAAGGCCGAATCACGTTCGAAATCCCACGGCGCACGACGACGAACGCCACGACGTTTCTCGGCAGGCAGATCCTTGGGCCAGTCATCCGGGATCAGCAATTCCACTGGATTGACGCGCTCCAGTTCCGCCAGCAGGTTTTCCCAGCCCTTGATTTCCAGCACGCTGAAGTTGCCACTGGTGATATCCAGCACCGCCAGGCCGAACAGGCGCTCGTCGCCCAGGACGGCGGCGATCAGGTTGTCCCGGCGCTCATCGAGCAGTGCTTCGTCGCTCACCGTGCCCGGGGTGATGATCCGCACTACCTGGCGATCCACCGGGCCTTTGCTGGTGGCCGGGTCGCCGACCTGCTCGCAGATCACCACCGACTCGCCGAGCTTTACCAGTTTCGCCAGATAACCTTCCGCCGCATGGTAAGGAATGCCGCACATCGGAATCGCCTGGCCGGCTGACTGCCCGCGAGCGGTCAGGGTGATGTCGAGGAGCTTGGCGGCCTTCTTCGCGTCTTCATAGAAGATCTCGTAGAAGTCGCCCATGCGATAGAACATAAGCTGGTCAGGGTGCTGGTTCTTTAGCCGCCAGTATTGCTGCATCATCGGCGTGTGCGAGGACAGGTCGGAGAGGGCTTTATTCATCGGATTGCCAGGAAAACTCATTCAAAAGGTGTGGGGCAAAAGCGAGCATGGGCACGGCTTTTCCGCGATGGGCGCAAGGTTACCATGGGCAGTCTGGTTGACGCAGGCATCACGGCCGGGTGACGTCTTCATTGATCAATCATGCATCGTTTATGCAATTAAGCATTTGTCGTGGCAAAAAACTTCGAGCATTATGCGCATTATGCAAAAACGCAATGTTTCGACCGTTTTAAGAGCGCTGCTCGATCAGCACGGTATCTCCCCAACGGAGCTTCACCGTCGCACCGGCGTGCCTCAATCCACCCTTTCGCGCATCCTCAGCGGGAAGATTGTCGACCCCTCTGATAAGCACATTTCGAAGATCGCCGAATACTTCGCCGTCAGTACCGATCAATTGCGTGGCCGGGTGCTTATCGCGCAGGCGTTGGGTGCCCGGCGTGAAGCCGCGCACTCGCAACTTACCGACATCAGTCTGTGGGACGACGATACCCCTATTGATGACGACGAGGTCTCGGTACCCTTTCTTCGCGAGGTTGAATTGGCTGCAGGATCAGGAAGATTCGTCATCGAAGAGAGCGAGCGCGCCAGCCTGCGCTTCGGCAAGCGTAGCTTGCGCCATAACGGCGTGCAGTTCGACCAGGCCAAATGCGTGACGGTGCGCGGCAACAGCATGCTGCCGGTGTTGCGCGACGGTGCCACGGTGGGCGTCAACGCCGGCAAGTGTGGGATTGGCGATATCGTCGATGGCGACCTCTATGCCATCAATCATAACGGCCAGTTGCGAGTGAAACAGCTGTATCGGCTGCCGACAGGGATTCGCCTGCGTAGCTTTAACCGCGAAGAGCATCCTGACGAGGACTACACCTTCCTGGAAATGCAGGAGGAGCAGATCCTGATCCTGGGTCATGTGTTCTGGTGGGGCATGTACGCGCGTTGACCTTTGGTTTGCCGCCTCGCAGGAGCCAGGCTTGCCGGCGAACCAGACACCGCGGTTTTTCTACAATACGGCGTTATCGTTGTTCGCCCTTACGAAGCTAAGTATTTTACTCGGCAAATAAATGCATTAATGCATTGACTGTATATGCATACATGCATAATCTTGCGCTTAACCGCTAGCATCACAAGCCAGGCATCCTGGAGGCCCGACATGACAAACGAGCAGCAACTGTTGCTGGACCTGCCTATCTGGCTCGTCGTCGCGCTCGCAGTGGTCAGTGGGGTGTCCGGGGAAATGTGGCGCGCCGACAAGGAGGGCGCCCGTGGCTGGTCATTGCTGAGACGCCTGGCTTTGCGTTCCGGGGCCTGCATGGTGTGCGGCGTCTCGGCGATGATGTTGCTGTACGCCGCCGGGATGTCGATCTGGGCCGCCGGCGCCTTCGGTTGTCTCACCGCGATAGCCGGGGCTGACATGGCCGTAGGATTGTACGGGCGCTGGGTGGCCAGGCGTATCGGTATCGATGATGCACCGCCGCGCGATTCTCGCTCCGACCCATAGTGAATGGCTGGCGCTCTGCGCGCTGCGCTGGCAACACAACACGGTGCAACAATTACCGGCGGGGCTTGCGTGGGAGAGGTGTGTAGTCTGGCGTTCGGGATGCGGCGTTCAATACGCTGCCGGCGTATTTCTCCCGGCGCCATCTTGCGAATTTCATGCATCAATCAAAGGAACGAGCGATGCGCCTCACTGAGCAGCAGTTACTCATGATTTTCCCAGGTGCCCGCACTCGATCGGGCCTGTTCATTCTCGCCCTCAATAACGCCATGGCACGTCGTAACATCAGTACCCCCGGGCGTATCGCCGCCTTCCTGGCGCAAATCGGCCACGAGTCGGGGCAACTGCAATATGTGCGAGAGTTGGGCGGCGAAAAATATCTCGAGAAATACGATACCGGGGACCTGGCCATGCGCCTGGGCAACTCCCCTGAAGCCGACGGCGACGGTCAACGCTATCGGGGGCGTGGGCTGATCCAGATCACCGGTCGCAGTAATTATCTGCAGTGCAGTCGGGCACTTTTTGGTGATGAGCGTTTGTTGCAGCAACCGGAACTGTTGGAGCTGCCACAATGGGCCGCTGAATCCGCGGCCTGGTTCTGGGAGCGAAACGGCCTCAATGAACTGGCCGACGTCGATGAGTTCAACAGTATTACTCGACGTATCAATGGCGGTTTGAACGGGCTGCAGGAACGTTTGCTGCTTTGGAAGCAGGCAAAGACGGTGTTGCTCCCGCCTGCAAGCCTGTGAGATGTGTGTCCGGGCGGCTCGTGCCTGTAACTTGCAAGCACCATTCGCTCGTGTACGTTAAGCCTCATTCCGTTCGATCAGGAGATGACCGTGAAAGAAATCACACAGCTGGCCGCTGAACTCGGCAGGCGCCTGCAGGTTCTCAATGCCCATGTCACCGCCGCCGAATCCTGTACGGGCGGGGGCATCAGCGAGGCGATTACCCGGATACCGGGTAGCTCGGCGTGGTTCGAGGCCGGTTATGTCACCTATTCCAACCGACAGAAGACGCTCCAGCTGAATGTGCCGCCCGAGCTGTTTTCAACGGTAGGGGCGGTCAGTCGGGAAGTGGTCGAGGCCATGGTCCGTGGTGCGCAGGAAAAAAGCCATGCGCGTTTTGCCGTGGCGGTCAGTGGGGTGGCGGGGCCGGACGGTGGTTCACCGAAGAAGCCGGTGGGCACCGTATGGCTGGCCTGGGGCGTCGACGATCAGGTGTTCAGCGAGGTGCAGCACTTTGCCGGTAACCGTGACGAGGTTCGCCGACAAACGGTGAAGGCCGCGCTAGAGGGGCTGCTGCGCCATGCTGCGGGAGAAATCTCAAATCAGGGGTAGGCGATCCGCAAACGCTGTGGAATAATACTGGCTACTTATACAGGTGTTGGCCGTCAGGCCTTATTGATTACGTGAGGACTTTAATGGACGACAACAAGAAGAAAGCCTTGGCTGCGGCCCTGGGTCAGATCGAACGTCAATTCGGCAAGGGTGCCGTAATGCGTATGGGCGATCAGGACCGTCAGGCGATTCCGGCCATCTCCACTGGCTCTCTGGGTCTGGACATCGCTTTGGGCATTGGCGGTCTGCCAAAAGGTCGCATTGTTGAAATCTACGGTCCTGAATCTTCCGGTAAAACCACACTGACATTGTCCGTGATCGCCCAGGCTCAGAAAGCCGGCGCGACCTGCGCATTCGTCGATGCCGAACACGCCCTGGACCCTGAGTACGCCGGCAAGCTGGGCGTCAACGTCGACGACCTGCTGGTGTCCCAGCCTGACACCGGTGAGCAAGCCCTGGAAATCACCGACATGCTGGTGCGTTCCAATGCGGTCGACGTGATCATCGTCGACTCCGTGGCGGCGTTGGTGCCGAAAGCTGAAATCGAAGGCGAAATGGGTGACATGCACGTGGGCCTGCAAGCCCGTCTGATGTCCCAGGCTCTGCGTAAAATCACCGGTAACATCAAGAACGCCAACTGCCTGGTGATCTTCATCAACCAGATCCGCATGAAAATCGGCGTGATGTTCGGTAGCCCGGAAACGACTACCGGTGGTAACGCTCTGAAGTTCTACGCGTCGGTTCGTCTGGATATCCGCCGCACGGGTGCGGTGAAAGAAGGTGATGAAGTCGTCGGTAGCGAGACCCGCGTCAAGGTTGTAAAGAACAAGGTGGCTTCGCCGTTCCGTCAGGCCGAGTTCCAGATTCTTTACGGCAAGGGCATCTACCTCAACGGCGAGATGATCGACCTGGGTGTTCTGCACGGTTTCGTCGAGAAGTCCGGCGCCTGGTATGCCTATAACGGCACCAAGATCGGTCAGGGTAAGGCCAACTCGGCCAAGTACCTGGCGGATAACCCGGATATTGCCGCAACGCTTGAGAAGCAACTGCGTGACAAACTGCTGTCTCCGGCTTCGGTAGCGGATGCCAAGGCTTCTGCGGTCAAAGAGACCGAAGACGATCTGGCTGATGCTGATATCTGA

Protein sequences of DBSCAN-SWA_1

>NZ_CP051487|1367561:1377072|1370052_1370376_-|WP_083348328.1|DBSCAN-SWA
MTFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAVAIFSEDEVPAGMENFIELNLELAEIWPNVTERKDPLPDAAEWDGKPGKIEHLER
>NZ_CP051487|1367561:1377072|1368524_1369532_+|WP_020795994.1|DBSCAN-SWA
MALSKEVPEFDIDDEVLLMEADVGTDSMSNDEGAAPPSVRAKSKHSATLKQHKYIDYTRALDATQLYLNEIGFSPLLSPEEEVHFARLSQSGDPAGRKRMIESNLRLVVKIARRYVNRGLSLLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMNQTRTIRLPIHVVKELNVYLRAARELTQKLDHEPSPEEIANLLEKPVAEVKRMLGLNERVSSVDVSLGPDSDKTLLDTLTDDRPTDPCELLQDDDLSQSIDQWLSELTDKQREVVVRRFGLRGHESSTLEDVGLEIGLTRERVRQIQVEGLKRLREILEKNGLSSESLFQ
>NZ_CP051487|1367561:1377072|1375429_1375930_+|WP_020796000.1|DBSCAN-SWA
MKEITQLAAELGRRLQVLNAHVTAAESCTGGGISEAITRIPGSSAWFEAGYVTYSNRQKTLQLNVPPELFSTVGAVSREVVEAMVRGAQEKSHARFAVAVSGVAGPDGGSPKKPVGTVWLAWGVDDQVFSEVQHFAGNRDEVRRQTVKAALEGLLRHAAGEISNQG
>NZ_CP051487|1367561:1377072|1367561_1368419_+|WP_033040739.1|DBSCAN-SWA
MSLTVIAQRMGTTSFQRLVTGLVMSTLLVGCSSNKSSDVRVVDRNNAAAQRPAVTTGQYVVRPKDTLFSIAFRYGWDYKALAARNNIAPPYTIHPGQTIRFDGRSGSTPTTVVSSSSSSPSSSSKTTVIRRSADGTTTTTPVVVPSVANKPAPTPLPPPGPAPTGWGWPSNGILIGKFSSNGSLNKGIDIAGDLGQPVLAASDGTVVYAGSGLRGYGELVIIKHSETYVSAYGHNRRLLVREGQQVKVGQTIAEMGSTGTDRVKLHFEIRRQGKPVDPLQFLPRR
>NZ_CP051487|1367561:1377072|1374772_1375339_+|WP_020795999.1|DBSCAN-SWA
MRLTEQQLLMIFPGARTRSGLFILALNNAMARRNISTPGRIAAFLAQIGHESGQLQYVRELGGEKYLEKYDTGDLAMRLGNSPEADGDGQRYRGRGLIQITGRSNYLQCSRALFGDERLLQQPELLELPQWAAESAAWFWERNGLNELADVDEFNSITRRINGGLNGLQERLLLWKQAKTVLLPPASL
>NZ_CP051487|1367561:1377072|1374245_1374593_+|WP_020795998.1|DBSCAN-SWA
MTNEQQLLLDLPIWLVVALAVVSGVSGEMWRADKEGARGWSLLRRLALRSGACMVCGVSAMMLLYAAGMSIWAAGAFGCLTAIAGADMAVGLYGRWVARRIGIDDAPPRDSRSDP
>NZ_CP051487|1367561:1377072|1373300_1374035_+|WP_168759134.1|DBSCAN-SWA
MQKRNVSTVLRALLDQHGISPTELHRRTGVPQSTLSRILSGKIVDPSDKHISKIAEYFAVSTDQLRGRVLIAQALGARREAAHSQLTDISLWDDDTPIDDDEVSVPFLREVELAAGSGRFVIEESERASLRFGKRSLRHNGVQFDQAKCVTVRGNSMLPVLRDGATVGVNAGKCGIGDIVDGDLYAINHNGQLRVKQLYRLPTGIRLRSFNREEHPDEDYTFLEMQEEQILILGHVFWWGMYAR
>NZ_CP051487|1367561:1377072|1370518_1373098_-|WP_033045311.1|DBSCAN-SWA
MNKALSDLSSHTPMMQQYWRLKNQHPDQLMFYRMGDFYEIFYEDAKKAAKLLDITLTARGQSAGQAIPMCGIPYHAAEGYLAKLVKLGESVVICEQVGDPATSKGPVDRQVVRIITPGTVSDEALLDERRDNLIAAVLGDERLFGLAVLDITSGNFSVLEIKGWENLLAELERVNPVELLIPDDWPKDLPAEKRRGVRRRAPWDFERDSAFKSLCQQFSTQDLKGFGCENLTLAIGAAGCLLAYAKETQRTALPHLRSLRHERLDDTVVLDGASRRNLELDTNLAGGRDNTLQSVVDRCQTAMGSRLLTRWLNRPLRDLNVLLARQTSITCLLDGYRFEKLQPQLKEIGDIERILARIGLRNARPRDLARLRDALGALPQLQAAMTELEAPHLNQLADTTSTYPELAALLEKAIIDNPPAVIRDGGVLKTGYDSELDELQSLSENAGQFLIDLEAREKARTGLSHLKVGYNRIHGYFIELPSKQAESAPADYIRRQTLKGAERFITPELKAFEDKALSAKSRALAREKMLYEALLEDLIAQLPPLQDTAAALAELDVLSNLAERALNLDLNCPRFVSEPCMRITQGRHPVVEQVLTTPFVANDLSLDDNTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAASCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATERSLVLMDEVGRGTSTFDGLSLAWAAAERLAHLRAYTLFATHYFELTVLPEAQPLVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPNEVIVRAREHLSRLEDTALPHEAPAPAKGKPATPQQSDMFASLPHPVLDELAKLDLDNMTPRRALEMLYTLKTRV
>NZ_CP051487|1367561:1377072|1376013_1377072_+|WP_008060630.1|DBSCAN-SWA
MDDNKKKALAAALGQIERQFGKGAVMRMGDQDRQAIPAISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAQAQKAGATCAFVDAEHALDPEYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDMHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVASPFRQAEFQILYGKGIYLNGEMIDLGVLHGFVEKSGAWYAYNGTKIGQGKANSAKYLADNPDIAATLEKQLRDKLLSPASVADAKASAVKETEDDLADADI

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033040739.1|1367561_1368419_+	peptidoglycan DD-metalloendopeptidase family protein	A0A0S2SXL7	Bacillus_phage	6.5e-06	33.3
WP_020795994.1|1368524_1369532_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.6e-34	35.8
WP_083348328.1|1370052_1370376_-	ferredoxin family protein	NA	NA	NA	NA
WP_033045311.1|1370518_1373098_-	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	3.1e-27	23.4
WP_168759134.1|1373300_1374035_+	helix-turn-helix transcriptional regulator	B5TK58	Pseudomonas_phage	1.8e-126	91.4
WP_020795998.1|1374245_1374593_+	hypothetical protein	B5TK61	Pseudomonas_phage	8.3e-45	78.1
WP_020795999.1|1374772_1375339_+	glycoside hydrolase family 19 protein	B5TK83	Pseudomonas_phage	3.9e-76	73.8
WP_020796000.1|1375429_1375930_+	CinA family protein	B5TK85	Pseudomonas_phage	1.4e-72	85.5
WP_008060630.1|1376013_1377072_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	2.7e-110	58.9

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP051487|2486844:2587244|DBSCAN-SWA
CATGCCAACTATTACTCTTCCCGACGGCAGTCAACGTTCATTCGATCACCCGGTTTCCGTAGCCGAGGTCGCCGCATCCATTGGTGCCGGCCTGGCCAAGGCCACGGTAGCGGGCAAGGTCGATGGCAAGCTGGTCGACGCCAGCGACATCATCAGCAGCGACGCCACGCTGCAAATCATCACGCCAAAGGATGAAGAGGGGCTGGAGATCATTCGCCACTCTTGCGCCCACCTGGTCGGTCATGCGGTCAAGCAACTGTACCCGACGGCCAAGATGGTCATTGGTCCGGTTATCGACGAAGGCTTCTATTACGACATCGCCTTCGAGCGTCCTTTCACCCCGGACGACCTGGCCGCCATCGAACAGCGCATGCAGCAGCTGATCGAAAAAGATTACGACGTGATCAAGAAAGTCACTCCGCGCGCCGAAGTGATCGAAGTGTTCAAGGCTCGCGGCGAAGACTACAAGCTGCGCCTGGTCGAGGACATGCCGAACGAGCAGGCCATGGGCCTGTACTATCACGAAGAATACGTCGACATGTGCCGCGGTCCGCACGTGCCGAACACGCGTTTCCTGAAATCCTTCAAACTGACCAAGTTGTCCGGCGCCTACTGGCGTGGCGATGCCAAGAACGAGCAATTGCAGCGCGTCTACGGCACCGCGTGGGCCGACAAGAAGCAGTTGGCCGCCTACATCCAGCGCATCGAAGAAGCTGAAAAGCGCGATCACCGCAAGATCGGCAAGCGCCTGGGCCTGTTCCACACCCAGGAAGAGTCGCCGGGCATGGTGTTCTGGCACCCGAACGGCTGGACCTTGTACCAGGTGCTCGAGCAGTACATGCGCAAGGTGCAGCGCGACAACGGCTACCTGGAGATCAAGACGCCCCAGGTCGTTGACCGCAGCCTGTGGGAGAAATCCGGGCACTGGGCCAACTACGCCGACAACATGTTCACCACCCAGTCGGAAAACCGCGACTACGCCATCAAGCCGATGAACTGCCCTTGCCACGTGCAAGTGTTCAACCAGGGCCTGAAAAGCTACCGCGAGCTGCCGATGCGCCTGGCCGAATTCGGTGCCTGCCACCGTAACGAGCCATCGGGTGCGCTGCACGGCATCATGCGCGTGCGCGCATTCACCCAGGACGACGCCCACATCTTCTGCACCGAAGAGCAGATGCAGGCTGAATCCGCTGCGTTCATCAAGCTGACCATGGACGTCTACGCCGATTTCGGCTTTAAAGATGTCGAGATGAAGTTGTCCACTCGTCCGGAAAAACGCGTGGGTTCCGACGAACTGTGGGATCGCGCCGAAGCGGCCTTGGCTGCAGCCCTTGATAGTGCTGGCCTGCCGTATGATCTACAGCCGGGTGAGGGCGCGTTCTACGGTCCGAAGATCGAATTCTCGCTAAAAGATTGCCTTGGCCGTGTCTGGCAGTGTGGTACTCTGCAGCTCGATTTTAACCTGCCTGTGCGTCTGGGTGCCGAATTCGTCTCCGAAGACAACAGCCGCAAGCATCCGGTGATGTTGCATCGGGCGATCCTGGGCTCCTTCGAACGTTTCGTTGGAATCCTGATCGAGCACTACGAGGGTGCATTCCCTGCGTGGCTAGCTCCGACCCAGGCAGTGATCATGAATATCACTGATAAGCAGGCAGATTTTGCCGCTGAAGTGGAAAAAACTCTCAACGAAAGCGGGTTTCGTGCCAAGTCTGACTTGAGAAATGAAAAGATCGGCTTTAAAATCCGCGAGCATACCTTGCTCAAGGTTCCTTATCTCTTGGTTATCGGAGATCGGGAAGTCGAGATGCAGACTGTCGCTGTGCGTACTCGTGAAGGTGCTGACCTGGGCTCTATGCCCGTCGCCCAGTTCGCTGAGTTCCTCGCGCAAGCGGTTTCCCGGCGTGGTCGCCAAGATTCGGAGTAATTATTATTAAGCGTGAAATGAGACAAGATAAACGAACTGCACCGAAAGCCCCGATCAACGAGAATATCTCGGCACGCGAGGTTCGGTTAATTGGGGCTGAAGGTGAACAGCTCGGGATTGTGTCAATTGAAGACGCGCTTCTTAAGGCTGAAGAGGCCAAGCTGGATCTGGTGGAGATTTCCGCCGATGCAGTACCACCTGTTTGCAAACTGATGGACTACGGCAAATCGATCTTCGAGAAGAAGAAGCAGATTGCTGCGGCCAAGAAAAACCAGAAGCAGATTCAGGTTAAAGAAATCAAGTTTCGTCCAGGGACGGAGGAAGGGGATTACCAGGTAAAACTGCGCAACCTGGTACGTTTCCTGAGTGATGGGGACAGGGCCAAGGTATCCTTGCGATTCCGCGGCCGTGAGATGGCCCACCAGGAGCTGGGGATGGAACTGCTCAAGCGAGTTGAAGGTGACTTGCTGGAGTACGGTTCGGTCGAACAGCATCCTAAGATGGAAGGACGCCAGCTGATCATGGTCATCGCCCCGAAAAAGAAGAAGTAATCAACAGGGCACGGCAGGCCTTCTGATTATGTTTATCAACTGAATGCGGAGTATCCGAACATGCCAAAAATGAAGACCAAAAGTGGTGCTGCTAAGCGGTTTCTGAAAACTGCTAACGGTATCAAGCACAAGCACGCTTTCAAGAGCCACATCCTGACCAAAATGTCGACCAAGCGTAAGCGTCAACTGCGCGGTAGCAGCTTGCTGCATCCGTCTGACGTGGCAAAAGTCGAGCGCATGCTGCGCCTTCGTTAATTTTAGTCAAGAATAGAGGAAGTAACTCATGGCTCGTGTAAAGCGTGGCGTCATTGCCCGTAAGCGTCACAAAAAAATTCTGAAACTTGCTAAAGGCTACTACGGCGCACGCTCCCGCGTATTCCGTGTTGCCAAGCAAGCGGTAATCAAGGCAGGCCAATACGCCTACCGTGACCGTCGTCAGAAAAAACGTCAGTTCCGCGCTCTGTGGATCGCTCGTATCAACGCTGGTGCTCGTATCAACGGTCTGTCCTACAGCCGTTTCATCGCCGGCCTGAAAAAAGCGTCCATCGAGATCGACCGTAAGGTTCTGGCTGATCTGGCAGTGAACGAAAAAGCGGCGTTTGCTGCGATTGTCGAGAAAGCTAAAGCCACCTTGGCTTAAGTACCCCCGACAGTCACCGGGCCTCACCTCTGTGGGGCCAGGTGTTAAACGTCATAAATAGGGGAAGAGCCTTCAAGCTCTTCCCCTATTTTGTATCTGGAGTCTGTACATGGAAAACCTGGATGCGCTCGTCTCTCAAGCACTAGAGGCTGTGCAAAGCGCTGAAGATATCAATGCCCTGGAGCAAATCCGGGTTCACTACCTTGGCAAGAAGGGCGAGTTGACTCAGGTGATGAAGACCCTGGGGAATTTGCCGGCAGAAGAGCGTCCGCAAGTCGGCGCCCTGATCAACGTTGCCAAGGAGCGTGTCACAGAGGTCCTCAATGCCCGCAAGGCACTGTTTGAAGAGGCCGACATGGCCGCCAAACTGTCTGCCGAGTCCATTGACGTGACCCTGCCTGGCCGTGGCCAGGCCTCGGGTGGTCTGCATCCGGTTACTCGCACTCTGGAACGTATCGAACAGTTCTTCACCCATATTGGCTACGGCATTGCCGAGGGCCCTGAGGTCGAAGACGACTACCACAACTTCGAAGCGCTCAACATCCCTGGCCATCACCCGGCCCGGTCGATGCATGACACCTTCTATTTCAATGCCAACATGTTGCTGCGCACCCATACCTCGCCGGTACAGGTCCGCACCATGGAGTCGAAACAGCCACCGATCCGCATCGTCTGCCCAGGCCGTGTGTACCGTAGCGACTCGGATATCACCCACTCGCCGATGTTCCACCAGGTCGAAGGCCTGCTGGTCGATCGCGACATCAATTTCGCCGACCTCAAAGGCACCATCGAAGAATTCCTGCGGGTGTTCTTCGAGAAAGAACTGGCCGTGCGTTTCCGTCCTTCCTACTTCCCGTTCACCGAGCCGTCGGCCGAAGTCGACATGGAATGCGTGATGTGCAGCGGTAAAGGTTGCCGCGTCTGCAAGCAGACCGGCTGGCTGGAAGTGATGGGCTGCGGCATGGTTCACCCGAACGTGCTGCGCATGTCCGGGATCGACCCGGAAGAGTTTTCGGGCTTCGCCTTCGGCATGGGCGTCGAGCGTCTGGCCATGCTGCGTTACGGCGTGAACGACTTGCGTCTGTTCTTCGACAACGACTTGCGGTTCCTCGCGCAATTTCGCTAGTCGTAACGAATTCTTAGGAGAGCAGGATGAAATTCAGTGAACAATGGCTGCGTGGCTGGGTAAGCCCGCAGGTAAGTCGCGACGAGCTGGTTGCCCGTCTGTCGATGGCCGGTCTTGAGGTCGATAGCGTGACGCCGGCCGCCGGCGAATTCACCGGTGTGATCGTTGGCGAGGTGCTGAGCACCGAGCAGCACCCGGACGCCGACAAGCTGCGCGTTTGCCAGGTCAGCAATGGCTCGCAGACCTTCCAGGTGGTTTGCGGCGCGCCAAACGTGCGCCCGGGCCTGAAGATCCCGTTCGCCACCCTCGGTGCCGAACTGCCGGGCGACTTCAAGATCAAGAAAGCCAAGCTGCGTGGCGTCGAATCCAATGGCATGCTGTGCTCGCAAGCCGAGCTGCAAGTGGGCGAGGGCAACGACGGCCTGATGGAACTGCCGGCGGATGCGCCGGTAGGCCAGGACATTCGTGAATACCTGGGCCTGGACGATGCCAGCATCGAAGTCGACCTGACGCCGAACCGTGGTGACTGCCTGTCCCTGGCCGGCCTGGCCCGCGAAGTCGGCGCGCTGTATGCCGCGCCGGTCACTCGTCCGGTAGTCGCCACTGTCGCGGCTGTGCACGATGAAGTGCGTTCGGTGGAAGTGCTGGCCCCTGCCGCCTGCCCGCGTTACCTGGGTCGCGTGATCCGTAACGTCGACCTGTCCAAGGCAACTCCGCTATGGATGGTCGAGCGCCTGCGCCGTGCCGACGTGCGCAGCATCGACGCCGCCGTCGATATCACCAACTACGTGATGCTGGAGCTGGGTCAACCGCTGCACGCCTTCGATCTCGCCGAAATCAATGGCGGCATCCGCGTGCGCATGGCCGAGGAAGGCGAGAAACTGGTTCTGCTCGACGGCCAGGAAGTCAGCCTGCGTAGCGATACGCTGGTGATCGCCGACCATACCCGTGCCCTGGCAATCGCCGGCGTCATGGGTGGCGAGCACAGTGGCGTGAACACCGCGACCACTCGCGATATCTTCCTGGAAAGCGCGTTCTTCGATCAGATCGCTGTCGCTGGCAAGGCCCGTTCCTATGGCCTGCACACCGACGCATCGCACCGTTACGAACGCGGTGTGGACTGGCAGCTTGCCCGTGAAGCCATGGAGCGCGCCACTGGCCTGCTGCTGGAAATCACCGGTGGCGAAGCCGGCCCGATCATCGAGACCGTCAGCGAGCAGCACCTGCCGAAGATTGCCCCGGTCACCCTGCGTGCCCAGCGCATCACCCAGATGCTGGGCATGGAAATGGATTCGGCCGAAGTCGAGCGTCTGCTCAACGCCTTGGGCCTGACCGTTACTGCCGATGGGGCAGGGCAGTGGCGCGTAGAAGTGCCAAGCCATCGTTTCGATATCAGCCTGGAAGTCGACCTGATCGAGGAACTGGCTCGCCTGTACGGCTACAACCGCCTGCCGGTTCGTTACCCGCAGGCGCGCCTGGCACCGCAAGCCAAGGCCGAAGCCCGTAGTGACCTGCCTGAGCTGCGCCGTCTGCTGGTCGCCCGTGGTTACCAGGAAGCGATCACCTACAGCTTCATCGATCCGAAACAGTTCGAGCTGTTCAATCCAGGTGTCGAGCCGCTGCTACTGGCCAACCCGATCTCGAACGACATGGCCGCCATGCGCTCGTCCTTGTGGCCAGGCCTGGTCAAGGCGCTGTCGCACAACCTGAACCGCCAGCAGGATCGCGTTCGTCTGTTCGAGAGCGGCCTGCGTTTCGTCGGCCAGCTCGAAGGGCTCAAGCAAGAGCCGATGCTCGCCGGTGTCGTGTGCGGCAGCCGTCTGCCGGAAGGCTGGGCGCAGGGTCGCGATACGGTCGACTTCTTCGACGTCAAGGCTGACGTGGAAGCGGTGTTGGGCTTTGCCGGTGCTCTGGATGCCTTCAGTTTCGTGCCGGGTAAACACCCTGCGTTGCACCCGGGTCAAACCGCGCGCATCGAGCGCGAAGGTCGTCTGGTCGGTTTCGTTGGCGCCATCCACCCAGAGTTGTCGAAAACCTTGGGCCTGGATCGTCCAGTCTTCGTTTTCGAGCTGGTCCTGGCGGAAGTGGCCTCGGGCAAAATGCCTAAATTCCAAGAGTTGTCGCGCTTTCCTGAAGTGCGTCGTGACCTTGCACTGATTGCGCACAAAGACGTCGCTGCCGCGGCAGTACTCGACGTAATCCGTGAAAATGCAGGCGAATGGCTGACAGACCTCAGGCTATTTGACGTGTATCAGGGTAAAGGCATTGATCCTGATAGAAAAAGCCTCGCAGTTGGCTTGACCTGGCAGCATCCATCGCGCACTCTTAATGACGATGAGGTGAATTCTACGACGCAAAACATCCTCACCTCGCTCGAACAAAGGTTGGACGCCACGTTAAGGAAGTGACGTATGGGGGCTTTGACGAAAGCTGAGATGGCGGAACGTCTGTATGAAGAGCTGGGCCTGAACAAGCGGGAAGCCAAGGAATTGGTAGAGCTGTTTTTCGAGGAAATCAGGCACGCTCTTGAAGACAACGAGCAGGTCAAATTGTCCGGTTTCGGCAATTTCGACCTTCGGGACAAACGCCAGCGGCCTGGCCGCAACCCGAAAACGGGGGAAGAAATCCCGATCACGGCTCGCCGTGTGGTCACCTTTCGTCCAGGGCAGAAGTTGAAGGCCCGAGTTGAGGCTTATGCTGGAACCAAGTCATAACGACGAACTTCCCGTCATCCCAGGCAAACGCTACTTCACCATTGGTGAAGTCAGCGAGCTGTGTGCGGTAAAACCACACGTGCTGCGCTACTGGGAGCAGGAGTTTCCTCAGCTCAACCCCGTCAAACGTCGCGGAAACCGCCGGTATTATCAGCGCCAGGACGTGCTGATGATCCGGCAGATCCGTGCGCTGCTGTACGATCAGGGTTTCACCATCGGCGGCGCACGCCTGCGCCTGTCCGGCGATGAAGCCAAAGACGACACCACCCAGTACAAACAGATGATCCGGCAGATGATTGCAGAGCTCGAAGATGTGCTGGTTGTCCTCAAGAAATAAATTTCTGCTTTTAAATACTTCCAGTTTTCAAAAGCTTGCGATATATTCTTGAGCGTTCCTCGAGGTGAGGAACAGGTTACACGCCTAGTCGGGGCGTAGCGCAGTCCGGTAGCGCACTAGCATGGGGTGCTAGGGGTCGAGTGTTCGAATCACTCCGTCCCGACCATTATTCCTGAGTAACATCAGACACTTAAGCCGATCAACCAGATCGGCTTTTTTGTGCCTGCGCAAAGCGCGCGCAAAACTGGCGCAAAACTCATTGAGGAAATGTCGTCTGATAGGGGCTGTATGGTCAATGTAGAGTTCAGCAAGAAACACGACGAACGATTTGAAAAGCACTTTTCGTCGCAGATGGATGACATAACACTCATCTTGAAATGTCATCTGATGTTGGAAGAAATGCTTCGCGATTTCTGCTCTGAGATGGTTCCCCAGCCCCAGTTTTTGAAAGACTCTCGCTTTACGTTTGCTCAGATCTTGGACCTCTCCCGGGCTTTGTACCCAGCGGAAATAAAACTTGGTGGCATGGTTGAGCTGTGGTCACTGTGCGAGAAGATCAATCGAATTCGCAACATCATGGCCCATGCGCTGGACCCGGACTCTTCCAAATTGGATAACCATAAGGCCGCTATCATTGAGGCTGTCAGGTTGCGAGGAGAGGGGAACACCTCTGCATTGGAGTTCGTGGGATGCCTCACACACGTCTTGGGTGCGTTTAGCCTGATACTGCAGGTTGGTGTTACACACAACAATGGCGAAGACTTTCGGGAAATTCCAAAAAAGTAGTTATGTGCCGGCGATCTCGCTAATGTCTAGATCTGGAATTGCCTCAGACCATACGATTTCGGCGTGATCCCGCTGGTAGTTTTTGGTCATGCTCTCGCTGGCGTGCCCGGCGATCTTCTGCCCGTCCTTTCCGGCTTTCTGATACAGATGCAGCGACAATGCTCGCACTTCGTGGAAGCCCGGCATTTCCTCTTCCTTCCATCCCTTGTAACACTCCGCCGCCTCCCGAGCCGCTTTGAAGGCCCGAGTCAAATATCGCTCTTCGACCTGCGTCCAGTGATCTTTTGTCTGCGCCTGTTTCTGCTTCTTGCGATCAGGACGGCGATGGACCAGGTACGGCGAGACGATGTCATCCCGGCATCGGCTGATCACCGCCTGGAGCTCATCGGTCACTTTGAACCGGATCCAGGCCGCATCAGTGGCCTTGGCCGTCTTCTGCTGCACCACATACAGAAACCCCTCCCGAACCCCATCGAATCGCATGTTGAGGATGTCGGTGCGTCGTTGCGCGGTGATCAGTGCCAAGTCGATTGCGTTCTGCAGCCAAGCCGGCGACTTTTCCCGAATAGCCTTCAATCCCTCGATGGTGTGTCGCTTGCGCTGTTTCTTCTCGATCCGGTTGATGGTACTGGTCGCCGGGTTATCCGGGCACAACCCCTTCGCCGCGGCGTGATTGAATATGTCGATGAGCAGGGCGCGGCACTGGTTGGCAGTGCGAGGGGTTAGGGCGTCCAACATCTCCGCGATCATGCGGATCGTGATCTGGTCCACGGCCTTGTCTTCGAAGTGCTTCCGAAAGCGCCGGAAGTGCACCGCATATAATCCCAAGGTGCCTTTGGCCAGATCTCGCGGCGGCAGGACGTCGCGCTCGTAAATGTCGAGAAACCCGGTGAACAGATCTGATGTCCTGCCCATGACGGCGCCAACCAAGTCGGCGCCACGCATGAATTCAAGGTTCAGTTGTTTCGCGGCATCAATAGCTTTGACGCGGTCGGCGCCGAATGGAAACCACTTCCCGTCGGTAGGCCGTCGATAGCGATAGGTCGAGCGCCGCGCGTCGTAGTACAGGTTCTGCGGAAGCCCCTTGTTTGCAGGATTGCGCGGCCGTGGCACCATCATGCAGCTCCTTTCAATACCATTGCGACCAGGTCGTTGCCGTTCGAGCGACTGAATGCGGCCCAGTCAACGTACCAGAGTTTCCCGATCTGCTCGCCGGGCACAATGCCATTGCGGATATGGTTGCGAATAGCTTGGGGGCATTGCGGGGTTCCGTTTTCTCCCCAGCGCCGGCGCTGAAACTCACTGATCTTAATCAGTTCTTTTTTCATAGGATGCTCCTTGCCGCGCGTGGCGGCAGAAGGTGGTTAAGATTTATTAGCGACCCACTTGATTAACTCCACTTCATCGTTCGGTCGAACCTTGAGATCACCCCAACTGAGCTCGCGCACGATTCCGAGAATTTCGCAGGCTGCCATTCCAACGCGTTCGGCGAGGCGTTGCAGGAATTAGCTATGATTTCGCAATGCCTGCTTTTCGTAGGGCAAAATCAGCCGCATAGGGTTCGACTTTTGGCGCACGTCATGCCCAGCATGCTTTCGAAAAGCATTGAGAATCCCTCGCCCGCGGTTCACCGGTAGGCATGAATGAATGGGGAACGTGGAACGGTGTGAGGCCTGTTGTTCTTTTTGCAAGGAGAGTGATGGTTCTTTTTTTTGTCACTGCTATTTGAGAAAAAATCTGAGGTCCTATCGTTGTAGGTTTGGCTGTGCCATCATTGGAAGGTTTGAATTTGTTCAGGATGAGCGATTGAGGGCTTGTGCATGAAACTTGTTTCATTGGAATACTCAGAATTTCTCGGAATGGGTGTTGCAAAAGCTCACTCTTGGCCAGAAAAACTTAATTGTTGGTCGAAATTCAACAGGTAAAACCCGGACTTTACATGTCCTTGCAAGTCTCGCTAGGGCCCTATCTAGCCCTCAAAGTGTGATGCCTCCGTCAGGTAATTATTACTGTGAATGGGATGGTTCAGGCGGGCAATCGTATATCTACGAGTATGTTGTGGAGGGAGGGGTCGTCAAGTCAGAGAAGCTGGCTATCGACGGGAAGATATTACTTGATAGAAAAGAGGGCGGTATAGGCGAAATTTTCTTCGAACAGGTCAACAACGGTCAGTTTTTGCCGTTTCAAACGCCTGTAAACGAATTTGCAATTACGATGCGTCGAGATACTTTACAACATTCATTCATTGAGCCACTTCACCAATGGGCTGCAGAAGTAAGGCATTACTATTTCGGTAGCTCGCTTGGGAAGGAACATCTAGCGATCTTTGCTCCAAATATGCCACCTGTTGATGAAAGAGATCCAAACCAGGTTGTTGGCTTATTCAAAAATGCAGTGAGAGATTATGGTGATGAGTTTGTAAATGCTGTGGTCAGCGATATGCGCTCGCTAAACTATAATATTGAGACTGTTGAAATTGGGTTTCCAGTTTCGGTGATACCTTCGGCAGTGCCTCCCGGTATAAATTGTGTGCGCGTTAAGGAGACTGGTGTAAGAGGTTATGTTGATCAGTTGACGATGTCACAGGGGATGTATAGGGTTCTTGCTCTGTTGATTAATATAAATTACCTTGTGGTAAAGAAGTCCAGTACTTGTCTTATAATCGACGATATTGGTGAGGGATTGGATTTCGAAAGAGCGTGTGGCTTGATTGGTGTGCTCAGGAAGAAAGCAGACGAGTCTGATATCCAAATCATTATGTCTACTAACGATCGGTTCGTGATGAATGAAGTGCCGCTGTCTGAATGGACCATACTGCATCGCGTTGGATCGACTGTCAGCGTAAGTAATTACATTAATTCTAAGGAGAAGTTTGATGAGTTTAGATTTACTGGGCTGAGCAATTTTTCTTTTTTTGAAATGGATTATCTGTCTGAAAGTGGAGAGGTGGAGAAATGAGGCGGCTGGCATTTTTTGTAGAGGGATATTCAGAAATGCTTTTCGTCGAACAGCTACTTTTGGAGATAGCGAATAGGTCCCAGGTCAGGATCGAGCAAAGGAGTATCAAAGGAGGCAGAAAAGTCCCCAGGAGCATGATTACCGTTAAAGCGGCGGCTCCCGACGAGGGGCAACAATATTTTGTGCTGATTTTCGATTGTGGAGGCGATCATCAGGTTCGCACTCGGTTAAAGGAAGAGCATCAAGGCCTCACGGAAGCGGGCTATGAGAAAATAATTTGTATTCGTGATGTCCGGCCTGACTTCAGTCGTGCCGAAATTGCCCAATTAGCGGCTGGTCTCGAGAAGGGGCTAATCCCAGGATTGGTGCCTGTAGACTTTATTCTATCTACGATGGAGCTTGAAGCCTGGTTCCTTGCTGAGTTTAACCATTACGTTAAGATTGATCCGTTGATCACAAATGAAGCAATATTCGCGGCAATCGGATTTGACCCTGCTATAGATGATCCGGCTACAAGAGATGAGCCAGCTAACGATTTGAGACAGTGTTATGCCCTCGGCGGGAAGACCTATGAAAAATCAGAGTCTGGCAGAACAATTAGTGCGCTAGATTACGCTTATATCTACACTAATTTGGTTTGCAGAATCCCCGAAATCCAACGAATTGCAAATCATATCGATGAGTTCCTGACTCCGGCTTAGAAATGGTACCTTCTATGTATGCGCAGCAGGCAATAGGGATAGAGTGTAACTAAGTTCCATCGTTACCCTGAGCCACTTAGAGCAATCATTGAGGGTGGATCAGGCCGGTTGCCCGGCCTGGAGCACTTGCACTTACTTTGGATCGAATGCACCCAGGGATAGAGCAGCGGCATTGCCGATCTTTTTCTGAAGCACCGTCTTGAACTCTTGGGCGATGTCCTCGCGCTGAACTTCTTCACCAACCCAGCGCAGTTTCAAAGCCGGTTGCGAGCTGCTGGTGATGACAGAAATCCGTAAATTGATCCGCTGCTCGGTCAAACCCTCGTACGGGATAGTGCTGAATAACAGGGCAGCTGGCAGCGTTTCTTTGCTTCGGGCCTCGATTTGATCCATGGCGCTACGGCTTGCGCTGGTATCGCCGACAGTGGTTTCGGATTCGTTGGTGGCCTTGATCGTGATCGTGCGTACAGCAGCGATGGCCCGGGCGACAGGAATTTCTTTGCCTTCGTCATCAACAGGGGTCAGGTACTGATGCCAGTCTTCGATCCAATCGCTCAGATCCTTCTGCGTCATGACCCGGCCACCAATGCCTTGAGCGGCCTTGTAGCCTGCCGACGGCTTCAACTTCAGAATCGCGCGGTCATCTGCGTGCCCTGGCAGTGCATCGGTGCCCAGGTTGAAGAGCAAAGTGCAGGTCATTTCGTCCTGGTCGATGAAGCCCTTGGCGGATGGGATTGCCCGGGCGGCGACATACGCGCTGAAGTCGGTCAGCGAATGGGTCGAGTAAATGCCACGGAAACGGCTGCGCCCAGCCTGCCATTTTTCCAAAGTGACCACCTGGCAGCCTTCGGGAAGGACGATGGCTGGGGTTTGAGTTGCCAACGCTTTACCGCTCGCTTCGAGCGCGGTGTCGATGATGAGCTGGATCGCTTCTTTGGTCAGAGACATTCTTCAGTTCCTTAGTGGTCGATCGATTAAGTGCGAGGGGTGATAGGCGCTTGTTCGCGGCTGAAGAGCTGATCGTGTTTCTCCGCGAAGAGAGTGATCTTGCCGCCGGAGCCGACATGCATCGGCGTGTCCAGGCTGGTGTTCTCGCTACGGGTACCGCGTTTGGTCGGCACCTTGTAGTCGAGCTTGTGCTTGATCTTCACTTGGCTGGATTCGCCGATCTGGCTGAAGTCCAGGGTGATCACCAGTTTGCCGGCCTTGCCGTGGTCAACAACCCCGGAGGCTACTTCGGACAGGGCGTGGCCGATTTGGCTGGCGAAAGCGCCGCCATTCAGTTCTTCAAGGAACTCGGCGGTATCGGTTGGGATTGGCATGGCTGTTTCTCCGGAATGGCCGACAGGCCGCTGGTTGAAGGTCGAATTGCGTCTGACGAAGGCGCTGTCGCACCTGGTTGCAAATGCGTCTCACGGTGGCCCCGGGAACTTGATGTTGTTCTCGCGGGAGATGAGCCTGGCGCGCTTGGTTTCCATGCCCATGGTCTTGGCGGCTTCGATGACGGTGTATCCGGCGTCGGCCAGTACCTTTAGGCGCGGCGCCTGCTTGTTGCGTTCGATGCGCAGCTTGTTGCTGTGGGAGGTGCCGAACATGGCCTCCTTCTCACCAGTTACGCCGGCGGCAATCTCCTGCGCTGTGCGGCCGGCTCCGAAGAATTGATCGAGCTGCTGGTTCAGGTTCGCAATGAGCGAGTCCCGCGGGTTGGGCATTGGTACGCCGATCATTTCCGATCCTCTGACAGTGAGACCTTGATGCTGTCGGCGCGCGCTTCCAGTTGCTGGGCGAAATTCACAGCTTCTTTCCAAGTCCAGCGGAAACCCTTCACCTTGCGGGTGGCCAATTCGATGATGTGATACGCCTTGCCCTTGGTGACGACCTGGTAGCGGATCTTTTGCACAGGCAGCTCCCTGCCGATCATTGAGTAGAATTCGGACGTCGCGATGACTGAGCGAAGGCGCAGGGCCTGAAGACCGGCGAAGCTCTGCTGCATGAGTGATTGCATGGCTTGTTCCTCGGTAAGGGTTGCGTGTATTCGTCAGCACTCGGCCGCCTGCTGGTTGCCGTTGGGCGTAGGGGAGAGTGCTGACGGATAAAGGCGGGCAAAAGAAAGGCCCGTGGACGTTCGGGCCTTTCGCAGATGCAGTGATTTTCTGGCTTTGGTCTATTTCATGGCGGTAGCCCTCTTGCGGGAGAAGTGGAAAAACTATTCCGGTTAGGTGCAATTTGTTTCCGGTGCCGCCGGATGCAGGGGGCCGCATTGCGCAGTGCAGAATCATCCGCATCCAGCAGGTATCAGCGGGCTGACGTGGCTCCGGGTCTTACCCGTGAGTGATGGATAGATCAGTAATCACGCAAATCGAACCATCCTCAGGATCGGTTGATTCGGAGTAGTCGATCTGGTTGTACACGCCGCCGTGGAAGGCGAGCGTTTTCGTGTCCCAAGTGTTGTCGAGGCGCATGATCGCGGAGGTGGATTTGGCGCCGTTGCAGCTTGCAGATACCGATACAGCGCCGCTCGAATTGGCGTGAATGTTGATCTTGAAGAGTGCGCCGAGCGGCACGTTTTCCAGTACTGTCGAGTTGACCGGATCGTCTTGCAGGTAGCTCGACCGGAACCCCATGGTGATTTTGCCTTTGTTCCAGAACACCTTTACTGGTGGGCGTTCAGAGCCCTGCACATGAATTTGGCCGATCACGACCTTCTGCAACGAATTGACCTTCGTCAGCCGCATTTCTTGACGGCACCAATGGTCTGCGGCACTGGCAAACAGCCAATAGCCAGGCTCTTTCCATTCACAGCGAGTCCGATGGACGCTTTTACTGGAAGCGCCAAGTGTGGGCGCTGTCATCTGCAGCGATCCGTCGGGAAGCATCGATATGACGCTTGGGCATTCGATCAACGCTCGCCAGCCGATCAAGTCCAGGGAGATAGGGTTTGTGTCGGAAATTGGAAGTGGGGTGGCGATGATGAAATTGCTGATATCTACAGTCATTGTCGATTCCTTATTTCATTTGATGTCACCTGTGCTCTGTTGAGCCCTTCGCTGATGTAGGCCTACATCCCGCTGCACCCTGTCGCCAAGGTGCAGAAGTGATGCTGTCCAATCAGCGATGGCGTCGAATTGATGAAGGGAGGCGGTCATGGAGGATCTGAATCCGTTCTTCATCGAACCATTCGGGCTCCAGCACCACATTGGCGCCTTTGGGGCTTGGCGGTTGAAGCAAGTAACGGTCGCAACCAGTGAGATACGTGGCCCGTGCGACAATGGTTCCGTAAAACTCGGTGACCTTGTCTTCGGCTTTCTGTCCAGGTCGATCATGACTTTTCCTTTGAGGTGAGTTACGCCGCGCGCTCCAGCGTTTCAGCGCGACGGGTGATTCGTATCTGGGCGATTCGAACTGAAGGCGGCCGGCGGTCGCGGCGGGCTGGTTCGACTGACTGGATGTTGGTCACAGCGTTCATGGTCATCAACGTGGCCAGGACAAAGCACATCGGGGAGATGATCTGCCGGCGCATTGCTTCAGCGACCAGAGCTGCCCGGCGGGTGACGCCGAGCTTGAACATTGCGTTGGTAAGGCGTTTCGCAACAGTGGCCGGCGAGATACCGGCCTCCCGGGCGATTTCCTTTGCAGTCAGCCCAAGGGCAACCCAAAGCAGGAACTGCAATTCTCGCGGTGCCAGGCCACGACCGAGGTGACCCTTCCATGCGCCATTTACGATTTCTGTTTCCATCGTCGTGACTCCCGGTTGTTTTCCCAATGCACCCGGCCAACCAGGTGCATCAGTGAAACTTTCCGTCCTATTGCCGCCGGAGGGGCGGGGCGCATTGCTTGCCGGGTCATTCACACGGTTCTGGCGTTTCACCATCGAGCAACCGTCCAGGTTGGTCCTGTCGTGGGCAGGCTTTCGGGTCTGTCTGCTCGCCGGTCGCCGGTAGAGGCAATGCGGTCTGTTGGTTTGTTGCGCTGACTGTTAAAGAGCGGCGGGTGACTTGACCCTTTGCTTCCGGTCCCGATGTGGGGACTGGGTTGCGATGGATGTAGTTAACCATCGGTATATTTTAACGTCAATACCGATGGTTAATTTATTTTCGGATGGTGTAGGATATGCTCCGCAACAACTGGATATGCATACAGCAATAGGGGGCAAGAATGGCGAAGCCGAAAAAGCAATCTCAACCAGTAGAGCGTCGTGAAATCAGCGGAATTGAAAGGCTTGGATTGCGCGTGTCATCGATGATCAACCACCCTGTGGCGCAGACCCAGCGATGGGTGACGATCCATCGTTTGGACACTGACGGAGACCGGGAGTGGGAGGAGGTGATGGGCTTGTTGTCCGAAACGGACGGCATAGACATGACGTTCAACGACGATGAGTCGGTGACACTGAGGTGGGAGGCGAGTACTGAAGAAGACCGGTCCGTGGCGGTTGCAGAAGAGGCTGAGGAGCCGGCCCCTTTCTGACAGGCACGAAAAAGCCCGCTCAATGGCGGGCTTTGAAATTGACTGGGTTTAACTCGTTTCGCCGTACGTCGCCAACGCTGAACACAAATTCTGCCTGTCCCTCTACCGAAGTAGTCGATAGAGGATGCTCACATGGTTGACGATCGAAAAAAACAAGCGCTTACCGATTGGCTGAAGCTTCTTGCTCAGCCGGAGATTCGTATGGACGCTGAAGAGCAATATGACGAGTTACTAAAGATGGCGGATGCAATGGAGCGGGAAGGGCTGGTTTCGGAAGTGGAGTGGCGACAGCTAATCAGGGATGCGGGCGTTGTTTTTGCGCAGGCAAGGGAAGGCCTGGAGGGCGGGACCTAGGGCACAAACCAAAAGCCCGCACTGGGCGGGCTGTTTTTTCTCACACTGGTCGCTACTCCTTCAGCTGAAGTCAGCATAGACCGTGTCTACGGGGTTGCAACTCTGAAACGAAAAGCCCGGCACTTCGCCGGGCTTTGATGCAGGTGGCCACATCAGCGGGTATGAGGACTTCATCAAGGACGAAGCTTTAAGTCATGCAAGACAGGAGCTTGGGTTGTTCAAAAAACGTAAAAAATCGAAACGCTAGGGTATGAATACAACGAGGAAGCTCTAGCTGCTGGTGAGTATGATGAGCTCCTGATCGAGGAATGAGGCCGGCGAAGGGGCAGGAGTCATTCTTGGCCCTTGTGCTTTACGCCCCAGCCCCTACAACTAACTCAGCCTTCTCCCGAAAAATCCCTTCCGCCCTAATACTTCGCATTTTTATCAGGAGGCAACTCTTGTTTCTTGATGAGCAATAGCTCGGCTTCTTCGTACTCTTGCTCCGTCATCGGCATGTTGCCCTCCGGGAGGAGAGGGGGCGCTGGCTCGTGAGCGCTGCAGCCAGCAAGCAAGGTCAGCGCAAAAAATGTCATCGCGTTTGTCATATCTATCCTTGGAACCAATAAAGCTCCTTGTTTTACAAATCTCTGCCACGCCTACTCAGGCTAGGCTCGCGTTATTTGCCCAGCCTTCATCTCTTCCACATATATTGTCAGCTTGTCGTCAGCCTCCTGAATGCTCACCGCAATTTTCATGAGCTCCCGAGAATCGTCTTCCTGAACCGTACTCTGACAGCTTGGTGGCAACTTTAAACAGGTCGACACCCGACCACTTCAGCAGATCCGCTGCCTGCTTGAGATCGTGCCACAGTTCTTGAGTCGGTTTGGTGAGTGCCATGCGGACCTCAGGCTAGCGACTCAGGATTTCGGGTGGATATTTCCGCCGATCGAGCATTAAGTCTTGCTTCGCCAGCTTTGAAAATAGTGATCAGGTGATGGATGGCCTGAGCGTCGATCTCATTGCCGGCCAGACTGAGCCGCTCAGCAATACGCTTGAGTTCCACCGCTGACCACTTTAGGTCAGAGGCAATGCCCTGAAGGTCGCGCTTTAGGTCTTGGTCTGGCTTCTTCAACGTCATATAGTCACACCAGGTTAGCGTTCCACACGAGCAGCACGCGCGCCTGGATGTAGGTGTCTTCTGCCTTGATTGTTTGAGGCGGATGCCGAGGGTTATCAGAGAGCATATTGATCTGTTCGTCTCCCAGCCACTGAAGCCGCTTGATGTAGAGATGTCCTTCCCAAGAGAACATGTAGATCCCATCACCAGTGAACTCACGGATGCTGATATCGACGAGGAGGGGGTCGCGGTGCTTGATCGTTGGCGCCATTGACTGACCCCACCCGGTCACCATCTTGAGATGGAAGTGCTCCTTGAAATCAACTCCCATCTCGCGAAGATGTTGCGGGCTCACCCTCACATCCTGGAGCATCTCCGGATAGTCGTGTGGAATTTGCCCGCCACCCATTGCAGCGCGCACATCGTAATGTGCGATCCACACCTCATCACCCATTACCCCGGGGCGATAGTAGTCGATCTCGATTGCGCCACCGCCTTCTTCAGCCTCGGCGACGGCAATTAAGCGTCTGCGAGCGTCTTCAGAAAGGTTTTTCCCGCTTCGACTCAGCATGTCCCGGATTGCGTCAGCCGCTGTCGCGCCGGAGGTATCGCCAACACTGGGGGCCTTGGTGACCGGGGCCCCGGTCAGGTTTCGAATTTCTTCGGCCAAGCGAGGACTGAAGGCCTCCACTGGCTCTTGAATTAAGCGCGCCAATACCGCCGCAAATTGAGCGTTTAGCGGGTTTATGCCTTTGAAATACAGGTTCACAGCTGCCGGTGTCATGCCAGCTGCATCAGCGATCTTCTTTTGGCTGAGCTTTAGCTCGTTCTTCTTTGAGAGGAACAGAGCATGCGCGGCCTCGCACTCCGCCATTCGGTCTGGAGGCAATATTCGTTTCTTTGTCATCGCGCGAATGTATACCAACGGTTAAAAATAAGAAGAAACCATCGGTATTGATTAAAAATTAACAGATGGTTAATATCGGCCTCATATATAACCCGAGGCTTGATCATGAATGAGACCCCCCTCGACAAGTTTGTTGCTGAAAAAGGGCAGTCCGAGGCCGCAAGGCTCCTTCGTGTGACCGCTCCGGCAATCCACAAAGCACTTAGCGTTAAAAGGGACATCCGTGTCCTTGAGCTTCCTGACGGCAGTTTTCAGGCCAAAGAGCAGCGCCCGTTCCCATCGCAGAAATCAGCCGCCTAACCCAGCCCTGTCACCGAATGCGGAAGTGAACCTATGGCCTACGACGATAAAGCCCACCGGCACGAGCACCAGGTGAAGGTGCGCCTCGATGACGAAGTCTTTCAGGAACTGAAGGACGTTGCTCGCGACATGAAGCTGCAACACAGCGTGCTTAGCCGAGAAATCATCGAGGCCGCGCTAGAGGTCAAGCGAACGCTCGGAGAGCTGCCGTTTGAACTGGAGAAACGACGCGCCTGAGAAGGCGACGGAGGGGGATTCATGCCCAGTGCAGTAGTTGACTTACGGAAGGGCGACACGGAGGACCTGGCGCGATGGGCGTCGGAGATCGGGATCACCCCGGATGCATTGGCCTCGCAGATTTTGCGACTAGCCATGCCGGGACTGAAAAAGGCAGCAAGCGACAACGTCCCAATCGACAGCAACGTGGTTGCCTTCAGTCCCAAGCGATGAGTACCGGCCCTTATTAGGGACCGCACGGTGCGGAAGGTGGACCGGTTGCAGATTTCAAGATTGGCGCTGGTCCCTGTTTCGGGACTGGAAGAAGAAATGGTCATGGGGGTCGTCCCTGATCGAGCTGTTGAAGCAAGTATCGCGGGAATAGGGCGGCACGGGCAGAACATCGGATTAGCTGTTGATTCATCCAGTGCTGAAATGACAGGCACAAAAAAGCCGGTGGCTAGACCGGCTTCTTCAAAACGCAAAACACTGAGGGGCCATTATGAACACGATCGTCGCTCCAAGCAATACGGTCACCATGTCGAGCCGTGAGATCGCCAATCTCACTAGCAAGCAGCACAAGGACGTCATTCGCGACATCCGCGTGATGCGCAAGGCGCTGTCGGATGATGGCGCAGATCTGCGCCATCTCCGGGAAGTGAAGGACGGGCGGGACTACACCGCTGAATTCCACCTTGATCGCGTCCTTACTGAAACCCTGTTGACCGGTTACAGCATCCCACTTCGTCATCGTGTCGTGACACGTTTAGGCGAACTGGAAAACCTGTCGCGACAGGTTGTCTCGATCCCTCAATCTCTCCCAGAAGCCCTCCGACTTGCCGCAGATCTCGCAGACAAGAACGGCGAGCTTCAACTTGTCATATCAAAGCAGGCCCCGAAGGTCGCCGCCATCAACAGGCTCGCTGCAGCCGGTGGCGCGATCTGCATCACTGACGCAGCCAAGCTGCTCAGTATGGCTCCGGCGCGCCTGTTCGCTTGGCTGGAGCAGCACCGCTGGATCTTCCGGCGCCACGGGTGCAAGCGCTGGGTTGCCTATCAGCCGCGCATCACCTCGGGTCACATGACCCACAAAGTTACAGCCCTCAAGCCGGATCCTGAAACCGGAATCGAGCGAGCTGCCTTCGACCCTATGGTCACCCCGAAAGGCCTAACCCGCCTCGCTGAACTTCTGCAGGAGGCCGCGTAATGGCCGGCGACTGGATCAAATTCGAACTCACCACCCTGGACAAGCCTGAGGTTTGCCAGATTGCGGACTTGGCCGATATCGACCCCGACGCTGTTGTCGGCAAATTGATGCGCGTGTGGGGATGGTTCGACCAACAAACCGAAAACGGTAACGCTCCGAGCGTTAGCAAAAAGTTACTTGATCGTCTCGTCGGCGTTATCGGCTTCTGCGAACACATGAAGTCGGTCGCCTGGATGATCGAGGCCGAGGGTGTGATCAGTCTTCCGCATTTCGAGCGGCACAACGGGAAGACCGCTAAAAACAGGCTTCTCACGGCAAAACGCGTTGCGAATCACAAGGCGAGTAACGGTAAAAGTAACGCTGCGAACGTTAGCGGTGCGTTACCTAAAGAAGATTTAGAGAAGAATAAAGAACCTCTCTCTGCGCAGGAGGCCGTCGACCCTCGCATGCCCAGCGAAATGACCCTCGACTGGGTACCGGATCAAACGCTGCTGAAAACCTACGCCTTGCACCGCGGGTTGTCCCTTGACCTGTTCACTGAGCAAGTTCGCGTCGCATTCACTGGTCACTACGAGCCTCAGCACCAGGTCAACACCCAGGCTGAATGGGTGGGCATGCTGGTCAAGTGGGTGAACAACGACAAGGCCCGGGCTGCTGCCGCTTCGAATGTGAAGCAATTCAAGCCGAAGCAGGCGCCTGCATCAGACTTTGATGATGACGACACCGAATGGCAGAACGGGGTGAACTCATGAAGACCGTCTCTGTGATTGCTCAAGACCTATGGGCGAAAGCCCAATCCGGTGAGTTCATCGCGGCGGGCGATGTACCTCCGGTGGCGAATGGAGCCCATAGCACGTTGGTGACAGCCATCAACGAGTTGTTCAAGGAACTGCGCTCCATTCGCTCGGCGTGGCGCCAGGCATGGCCCGACAAAGAAACCTACCGTGCTTCTAAGCGCCAATGGTTTCAAGCATTTCTCGAGGAAGGCATCTGCACTCAGGGTCAGATCGACTTCGGCATGACTCAGGTTCGCAAACAGCCCGGTGACTTCATTCCAAGCCCTGGCCAGTTCATCGAATGGTGCAAGCCAACCCCCGAAATGCTTGGTCTGCCACCGCTCGCTGCGGCGCACCGCGAGGCGTGTCGCAATGCTCACCCGGGCATGGCTGGCCAGGGTAAGTGGTCGCATGATGCGGTGTGGCACACCGCCAAGGAATGCGGATTCGAAAGCCTGAATAAGCTCGATACCCCGCTCAGCTTGAAGCTATTCGAACGCAACTACACGATCACCATCCGCCGATTGCTTGCCGGCTTGCCACTCCAGGCGATGCCCAAGGCTCTACCTGCCCGTGCCGCAGGAAGGGCGACGCCAGAAGTTGGCCAAGGAGCTCTTGCACAGTTGCGCGCGAAACTGGGAGGTGCCCGTGATTAATCCGTATCTCGCACCTACCGACCCGGTCGAGTACCGGTATGCGGTGCACTGCTGCGCCTACAAGTTGGATCTCACCGATAAACCAGATCGCGCTGTAGCGCTGTTCGAGCATCGCTCTGCTGCCGAGAAGTTCGGCGGTCTGATGTGGCCGAGCACTTTCGAAGTAATCGACATCACCACAGGAGAGAAGGCATGAACGACATCCTGCTTCATCTGTACATCGCGTTCATGACGGTCGCCGCCGTCGGCCTTTGGTGGGGCATCCGCCGTCTCGAGCGCCGTGCCCGAATCGCGCGGGGTAATCGCGAATGACGCCCGTCGTAATGAAGCAGTTCAAGCAGAAACCGGTACGCGCCAAGTCTATCGACCGCGAAGGGCAGGAACAGGCCGCGCTGATGACCGAGCTGCGGATCCGTATGCCGGATGTCGCTGACCTGATCTTTCACGTCCCGAACGGCGGGCATCGCGTGAAAGCCGTTGCTGCGAAGTTGAAGGCTCAGGGTGTGAAAGCCGGCATACCTGATCTGGTTCTGCCGATGGCTCGCGGCGGGTTCTTCGGTCTGTACATCGAATTCAAGGCCACGCCACCAAACGACGCCGCGATTTCGTCCAGCCAGCACGAACGCATTCGCAAGCTCAATGCTCAGGGTTATCTGGCGGTGGTGTGCCGTGGGCACTTCGACACGATGGAGCAGATCCGCGCCTACCTGCGGCTCGCTCCTACAGTGGTGGCCGCATGACCAGCGCCGCCGTGAAGATGTCCGACGCCGAAATCAAACGGCAGGCTTCCGGCAATGTCCGGGATTTGCGCGACGTCGAGAATCGCGGCCTGTACCTGCGTTTCACCAAGGCTCGTGCCCGGGCGTCCTGGTACTTGGTGACCAAGGGCGAATGGAACCTGATCGGCAGCTATCCCGACCTCAACACCAAGCAGGTGGTTGCTGCGCTGCCGGCCATCCGCCTGCGCCTGGAGGCCGGCACTGGCGCGAATCTGTCGAAGTGGGTCAATGTCGGCGAGCTGCTGACCTGGTACGCCGAGCGCATGTCGCGCGACCGCAACCTGTCGAGCAAGCGCAAGAAGACCGGCGCCTCGGCGATCAAATGCCACCTGATTCCACGCCTGGGCGAGCTTCCACTGACCGGTATCGACAAGGCAACACTCGACAGCCAGCTCATGTGGCCGCTGCAGGAAAGCATTTCCATCGACTACGTGCGCTCGGTGTTTCAGCTGTTGGCCCTGGCCTTCCGGCAGGCGTTCAAGCTGGGGCTGATCTCGGCCAACCCGATGGCGACCATCAAGTTCAGCGACTTCTCGAAGGCCAAGGTCGGGATCAAGCCGTCGCGCCTGCGTGGGGTTCAGCTGTCGGGGCTGCTGGAGCAGCTGGCCGCTGTCATGGAGCCCGCGCCGCTGGACGCCATGCTCGCCTTGATGATGCTCTGCCACGGCACGCGCATCGGCGAAACCCGGCAGGCGCGCTGGTCGCACATCAGCCTTGCTGAGCGTGAGTGGTTCATTCCAGCCGAACACACCAAAACCGGTGTTGAGCATCACCTGCCATTGACCGAGCAAGTGTGCGCGCTGCTCGTCAGTTATCGCGAAGGCCAGTACGCCAAGGGCTACGACGGCCAGTTCCTGTTCCCGGCGCGCAACGGCAAGGCCCTGAGTGAAGGCCAGGCCAGCGCCGTGTTCGTGCGGTTGGGGCAGGGCGAGTGGACCAGCCATGACCTGCGCAAGGTGGCCCGCACCGGTTGGGCAGACATCGGCATCGACTACCTGATTGGTGAGCTGCTGATCAACCACGCCATGGTGCACAACGTGAAGGTGTACATCCAGTCGGACGTGATGAGTCGCAAGCGTGATGCCCTAGAGCAGTGGCACGCCCATCTAGACCAGAAGGGTTTTGCCCTGATTCACGGATTGACCGGCTTTAGAACGGGAGATTCCGGTAATGCGCTGGAAGCCGCAGAACATAAGGGCTGCGAGGCCAATCAAGAATCAACCATAGGCGAGGTTTAAAAATGATGATTCAGGGTGATTTTCCGGACCTCGCCGAACTGCAACGGCTCGCCGAACTTGTGCCGGCTCTTGATGAGCGCCGCTGTCTGGTGGATCCGGAAGAGCACGGCCGGCGCTTTGTCGAAGAGGTCGTTCGGTTGTTCGATACCGATTACGGCATGGCAAAAGCGTTTATTTCTGAGGTCGAACGCCTCCAGGCCGAGAACGAGGCGCTGCGCAAGGCTGTGAACTTTTCGGTGGAGATGTTTGGAAAAATTACGAGCGGTGACGGATCTGGGCATGCCGATCTGTCGCGGGCGGTGCTGCGCATCGCCGGAGCCGCCCTGGCTGGTGATGATGTATTCCGCAAGGACGCCGAGCGGTATCGCTGGCTCCAGCGCCGCCTGATAGGAGTGCTGAAGGATTGGGATGATCGAGGGAAGGGCATGCTGGGGTTGTCCTTCATGATTCCGGGTGATGCATGGCGCACCTGCGACGAAAACATCGACGCCGCAATGGCGGGGGGCGGGCGGTGATGAAAAAGAACCACGGTCCAGCGTTTCGTGCCGCTCAACTCGATCTGGCTCGTTGCCCTGTCTGCAAGGGTAGGGCAGTGGTGAAGGGTGTCTTCCACGACTTGGCCTGCGTGCAGTGCAACGCCTCCGGTTGGATTGCTGCCGAGACTGGTGAGTCGCTGCCGCTGGAGATCCTGGTAACGCAGCTGAGCATTCGACTCCAGGCCGCAGATCAGCAGATCGAACAGTTGAAGAGCGGGTCGCTGATGGCCGGCCCGGCAGCGCAGTACGAACACAATAACCGTCGCGGTGCCGGCGGATCGAATTACACAGGGGATTGATCAATGGCCAGAACGAAGAGCTTCACCGAGCGCACATCGGAAGACCTGCTGGAGCATTGGGGTCGCTGGGTTGTACTGGGCTCAGGCGTATCCTGCTGCGCCTCTCGCGAGAACACCCTGCATACGCCGATGATCACTGATGACGACGCCTTGATGATTGACGGCCTGATGGGTCGTTTGTTGAAACGATACCCCGAATGCGGAAACGTGCTGATGAAGTACTACACTGCCCGGGATAAGGCGCTGGTCGATGTGGGCAAGAAGTTGGGTTTCGGTGAAGAGAAGACCCGGCAACTCTGGAAGGCTGGCATTGCCTGGATCGATGGTGCTTTAGATTTTCGTCGTGCGGCCGCTTGACAGGGCCGGGGGCGAGCTATAGATTTCAGTTACTTTGCGGTTTTTCCGCGAGCAAAGCCCGACTCATAGGTCGGGCTTTTTCGTTTCTGATACTCGTCAGATCCGAACAGCGAGTTCGCCGGTCGCAACGATTTCGTACTCCGTTTCGCTTTTTTTGTTCGCATTGCCGCCGCCAGCTACTTTGTATTGCTTCATTCCGTTGGCCCAACCGTTGTCCGCAGGGTTCAGGAATTCTTGGTAGATCTGGTGCGTGAACTCAGCTATGCCATAGACCTTTCCCGATTCGGTTTTGACTTTGAAAGCGTCTGTTTGCTGTTGCCGTTGTTTCATTGCTTCTTCCTTGTGGGTTGAGATAGAGAGGCGACGATAGTACTTAGCTGTTGCTCATTTGAGCCAGCCCACTTTTTAGTCAAAATTTCCATAGCCTCGGCATTTGCCGGGGCTTTTTCGTTTTCGGCCCACCACACCCATTGCTCCGAGCTGGGAGTGCCGCTGGGGCTGATTCAATCCTGTCATGCAGTCGGAGTCGAGCGCATGGATCTTCTGCACCGCCTGTTCGACAAAGCTGAGTGGCTGGTCGCGGGCCTGATTGGTGCCATCGTCGCAAGTTGGTGGCACAAGGACGACCTCACTGATTGGCGAGCCTGGGCAATATTCTTGGTCACTGGAGTGGCCTGCTCTCTGTATCTGACAGGCATGGTCAGCGCATACCTCGGTGTGACTGAGCCGAGCATCGTCGCCGGCATCGGTTTTCTACTTGGCACTTTCGGCGGCTCCCTCCTGGCGGCGATCAATCGCGCCATTAAAGCCGCGGATCTTTGGGCGCTCATCCGCCAGAGGTTCGGCGGAGGTAATCCACCATGAATTACGAATTGATCAGCTCCATCGCCTGTGGGGTGATAGCGCTGTGGGCAACCTGGTGTGTGCTGAGTGGCAGGGTCAGGGATGGCATCCTCGGGAAGCTGATCTACTCGGCGATCGCCATCAGTGGTTTCGTGGTGATGACCCGAAACCAGAACATCTTCATCGGCCCGACGACTGCCGGCCTGACGCTGCATGTGTCTCTGGCGTTGGCCGGGATAAGGCATGTTTTCATGGTTATCTGGTGGCAGAGAGTCAAGGCTTGGCTGTGCCGCACATTGAATTGCGAGCATTGCCTGGGCTGCAATAAAGGCCATGCACCAGATGACCGCCATAAAAGCTGAGGTGCAACATGGTCAGGATCGATGCCGGCACCAATGTGGAAGAGCTTTCGAAGGCCTTGCGCACATTGGGCGCCAAGCAACTGCCTTTCGCATTTGCGCTGATGGCTACAAAGTTGGCCATGCTGGTGAAAAAGGGCGAGCTCTCGGTAATGAGAGAGAGGCTTGATCGACCGACCGCCACCACACTGAACAGCCTTTATGTGAAGGCCGCCAAGAAGGGCAATCCCGAGGCCCGCACTTTCTTCAAAGATGCATGGACGTCTGGCGTTCCTGCTGACACCTATCTGCAACAAGCAGTAAAGGGTGGTCGTCGGCCTCACAAGCGTTTCGAGAAAGCCCTTATCGCGAAAGGTCTGATGAACTCGGGGCAGTACGCAATCCCAGCACCATCGGCAGTCAACCAATTCGGCAACGTCCCGCGCGGCACGATCATGAAGATCCTGTCGGGCCTCGGTGCGGCCGAAACGGTGAGTGGTGTGCAGGCCAACGCTACTGGCAGTAAACGCAGTAAGCGCAAGGGCAACGCCGACAAGTACTTCTCTGGTGATGTCGATGGTACCCAAGGTATTTGGGAGAGGAAGAAGACGGCGTTCGGTGATGCTGTTCGCCCTGTCTTCATCTTCAGTGACAGTGAGCCTGGGTATCGAGTGATCGTTCCGTTCTACAAGATCGCAGACAACATCGTGAAGGCGAACCGTGAGCGTGAGTTCGCCAGCGCGATGGATCAGGCGCTGTCCACAGCCCGATGATGGCCGGCAGGGGGAGGGGTACCCCCCCTTTGGGTCCTTCCCGGACCCCCAGCCCCATGCGGGTAATTCGGGCCCCGCCCATCAAATATGTATGACCTTTTTTCAGAGGTTGGTTGTTGTTTAATCATGGCCAAAAACGAAACAACCAAACAGCGCGGGTGGTTGAACAAATCCGAGATGGCCTCGAGCCTCGGGATTTCCCCGCAAGCCTTTGACAAATGGGGAGTTGCGCCCGTCGCACGCATCGGTCGAGAGGCGTTCTACACCGTGCAAAACGTGGTAGAAAATCGCGTTGACCACTCACAACGGAAACAACAACCGGCGGGTGAGGGAACCGAAGGTGTCGATCCGATGATCGAGTACAAGCTGCTCGAAGAGCGTCGAGGCCTGACCGCTGCCCAACGGATCGCCCAGGAGAAGAAGAACCTGGTGCTGGATAAGCAACTGGTGCCGGTTCCATTCGCCACATTCGCACTCGCCAAAATCGCTGCACAGATCGGCTCGAAACTGGACACCGTCGGCAAGACCGTCACTCGGCGTCACCCGGAGGTTGACCCTCGGATCATCGAGTCGGTGGAGCGGGAGATTGCGCTTGCTCGAAATATTGCTGCCAGCTTTGGTGAGCAACTTCCGGAATTATTAGATGAGTACGTTGAGTCCATGGCTGAATGATCTGCGTAAGTCGATCAAGCTAGGACTCCAGGCGCTCTACAAGGAACCACCGCAAACCGCCGTCGAGTGGGCGGATGCAAATTTCTACATGTCTGCCGAGTCCTCCTACAACGAGGGCAAGTGGACGACCGAGCCGTTTCAGGTTGCGATCCTGAACAGCATGGGCAACGACCTGATCAACGTCGTCAACTTCATCAAGTCGGCGCGGATCGGTTACACCAAGCTGTTGATGGCGAACATCGGCTACAAGATCCAGCACAAGCGCCGCAACGTCATGATGTGGAGCCCGACCGACCCGGACGCCGAGGACATCAGCAAAAGCCACGTCAACGGTATGATCCGTGACGTTCCTGTGCTTGGCGACTTGGCTCCTTGGTTCGGCCGCAAGCACAGCGACAACACCCTGGACCAGAAGATATTCGCCAACCGGCGAACCCTCTGGATTCGCGGAGGCAAGGCTTCGCGCAACTACCGTGAGAAATCCGCTGACGAGGTGATCTACGACGAGCTCTCGAACTTTGACGAAAGCGTCGAGGGTGAGGGCGCGCCGATCACGCTGGGCGACAAGCGACTCAACGGTGCGATCTACCCGAAGTCGATTCGTGGCTCTACGCCAAAACGTGTCGGCTCCTGCCAGATCACCAAGGCCGTCGAAGAGTCACCGTACCTGCTCAAATTTCACATTGACTGCCCGCACTGCCGGCAAGAGCAGACGCTCAAGTGGGGCGGCAAGGATTGCGAGTTCGGCCTGAAGTGGGAAAAGAACGCGCTGGGTGAGGCCGAGAAAGCCTGGTACGTGTGCGAACACGCGGCTTGCATCATCTGGCACAACGAAATGGTCGAGGCGTCCAAGACGGGCCGGTGGATCTGCGAGCACACCGGTATCTGGACCCGCGACGGCATGGACTGGTTTGGGGCGGATGACGAAATCATCCGCACGCCACGCTCGGTCAGCTTCAGTATCTGGGCGATCTACAGCACCTGGAGTACCTGGCTCAGCCTGGCCGAGGAATGGCTGAAGATCAAAGGCGATGTGTCGAAGCTCATCACCTTCATCAACACGACCCGCGGCGAAACGTGGGACGACGACCAGGGCGAGAAGCTTGACTCGGAAGTTCTGTACGGTCGCCGCGAAGTTTTCCCACAGGTACCGGCCCTCGGTCTGGTCCTTGTCGGTGGTATCGATACGCAGGACGACCGTTTCGAGGGTCGCGTATGGGCGTTCGGTCCCGGCGAGGAAGCCTGGTTGGTCCATCGTTTCATCTTGATGGGCGACCCGGCCAGCGAAGAACTACGCCGCAAGGTGGGGCTTGAGTTGCACCGGCAGTTCACCCGCGTGGACGGCACCATCATGAAGGTGGAGCGCTGGACCTGGGACGCCGGCGGCCACTATGCCGACGAGGTCTATGCGGAGAGCCGCAAGCACGGCGTGCACTGGGTTGTTCCAATCCGTGGCGCGACTGTCTACGGCAAGCCGATCGCAAACTTCCCGCGCACAAAGAACAAGGTGCACAAGGTCTACCTCACCGAGGTCGGTACCGACAACGCCAAAGAGCTGCTCTACAGCCGGATGGGGCTCCCCGTCGATACGGCTGCGTCCCAGGCGGGCATGTCTCAGCCCGGGGTGGTTCACCTTCCGGCCAACGACGCGATCTGCGACGAATCGGAAGTGAAGCAACTCACCTCTGAAAAAAAGAAAGCAGCCATATCCAAAGGCAAGCGCGTGATGCGCTGGGACAGCGGCGGCCGCCGAAACGAGGCTCTCGACTGCTTCGTGTACGCGCTCGCCGCGCTGCGCATCTGCCAGCAGCGGTTCGGGCTTGATCTCGATCTGCTGGTTGCAGCTGTAACTGGCGGCAATGAACCGGACGCTGAAGAACGGCCGCGGAAGAAATCAACCTTCTGGTAGCGAGACTTATGGCTTTCACAATCGAGCAGTACCAGGCCTTGCAAGCGGCCATCGCCGAAGGCGCGTTGTCCGTCCGCTACGCCGACAAGAGCGTCACCTACCGGTCACTCGACGAGATGATCCGGATTCTAAAGCTGATGGCCAATGATCTCGGGCTATCCGCGAACAACGACGGCGGACGCCGCTTCACATCATTCTCGAAAGGATTTTACCCATGAGCATGCTCGACAGCTTGTTCCCTGGGTACGCCGCGAAGCGCTCGGACGCGCGACTGAAAAAGCTGCGCACCGAGATGACGATGGACCTAATTAAGCGTCGGTTCGAGGGCGCGGCCGGCGGTCGCAGAAACGATAGGTGGCGTGCCACTGGCGCCGATGCGAACGCAGAGAATGCACCGGCTCTTGCGAAGCTTCGCAATCGAGCGCGCGACCAGCGCCGTAACAACCCGTTCGCTGAGCGAGCTATCACCGGCATCGCTGATAACGCCGTAGGCGCCGGTATCGTGCCGCTGCCATTGGCCAAGCGCGACCGTGATGGTCTGCGTTTGATGGACTTGTGGAAGGCTTGGGCAGAAACCACCTGCTGCGATGCTGACGGCCTGGAAGATTTCTACGGCCTGCAACACATGATCATGGAGGCCGTCGCTGAAAGCGGCGAATGCTTGATCCGTCGCCGGCGTCGATTCAGTTCCGACGGTCTGCCTGTCCCGGTTCAACTCCAGGTTCTTGAGGCTGACTTTCTCGACGAGAACAAGGCAGCAATCCTTGGCCTGAATGAAGTCATTCAGGGGGTCGAGTTCGACGCCCTAGGTCGCCGAGTGGCTTACTGGTTGTTCGATAAACATCCCGGCTCCAATGCGACATGGGGCTCCCTGCAGTCCACGCGGGTTCCCGCCGAAGATGTCATTCATGTGTTCTTGCGCAAGCGGCCAGGCCAGGCCCGTGGTTACACCTGGCTGGCGCCGGTGATCCAGCGCATGAGTAGCTTCGACGAGATGGAAGATGCCGTCATGGAGCAGGCGAAGATAGCTGCCTGCTTTGCGGCGTTCGTTACCAAGGACCCTGAAACCCATACGGGTGTGAAGAAGGGTCCTGCGCTCATTGATCGAATGGAGCCTGGGATTGTTCAGGAATTGTCGATGGGGGAAGCGGTTAGCTTCGGTACGCCGCCCACCTTCAATGGATACACAACCTATTCCTGGCAAGCGCTTCATGCCATCGCTGTCGGCCTTGGCGTCCCTTACGAGCTGCTGACCGGTGACCTCAAGGGGGTCAACTTTTCCAGCGGTCGTATGGGGTGGCTCAACTTTGCCCGGCGCGTAGACGTCTGGCAGTGGCGAATGCTGATCCCTCAGCTATGCGATCAGGTCTGGCGTTGGTTCATGGAGGCTCAAGTTCTGCTGCCCGGCGGCGTCACTGATGACGTCAAGGCTTACTGGGTTCCCCCTCGGCGCGACATGGTCGATCCGAAGTCGGAAACCGAAAACGTTATCACGCGAGTTCGCAATGGACTCACTACCTGGCCCGACGCTTTGCGGGAATTGGGCATCACAGACCCGAAACGGCACGCAGAGCAAATCCAGAAAGCCAACGAAATGATCGACGAATACGGCCTGGTCCTGGATTGCGACCCGCGCCGAGTCGCGGCCGCCGGCTCACCCAGTCAGCCGCCAACCAACGAAGAGAAACCAGACGATGCCAACTCCGAATCAGGCGACGACAAACAAGACGCATGAAACACCAATGCTCAGCCTGCGCGCCGCCGTTCGTGCGGGATCGGTAGACGTTGACGCGCGTACTGTCGAACTTACCTGGACTACTGGCGCAAAAGGTCGGCGCTGGTCTTGGGATGTTGGCAGTTACATGGAAGAGCTAGAGGTCAGCGAAGACGCTGTCCGGCTGGATCGCCTTAATAATGGTGCACCGTTCCTCAACGCCCATAACTCCTATGAGCTGGACGCCGTGATCGGTGTCGTCGAAAAGGCCTGGATCGAGGGCGCTGAAGGGCGTGCTCTTATCCGCTTCAGCCAACGGGATGACGTCGAAAAGATCTTCAAGGATGTTCAAGACGGAATCCTTCGCAACATTAGCGTCGGGTATGCGGTGCACCGATACGAGGTGACCGAAAGCGCCGACGACAAGCTGCCGACCTATCGCGCCGTCGATTGGGAGCCCATGGAAATTTCCTTGGTTCCGATCGGCTTCGACGACGGCGGCAAGTTCCGCAGCGCCAAGACTGCCGCTGATTACCAGGGCCAACGCTTCAACACCATTTTTGAAGTTCGCGAGGCTCCACAGCCTCCCGACCAACCGGCCGCCGTGGCCAACACCACCGAGGAAAACCCGATGACTGAAGAAGAAAAGCGCGCGGCCGAGGAGCAGATCCGCCGGCAAGCGGAAGAGGCTGAGCGCAAACGCAGCCTGACCATTCGCCAGATGGCGAAAAAGGTTGGCCTAGGTGACGATGTCGCTGATGACCTGGTAGCCCGCGGCGTATCGATCGCGGATGCCAGTGCTGCCCTGATCGACAAAGTGGCCGAACGCCAGGCTGGCAGCCAGACCGAAACACGCAACAGTCAGCCTACCGTCGTCGGTGGTTTGGATCAGACCGTTCTGACTGCTAAACGCGAAGCGATGCAGAACGCGTTGCTCAACCGTTGCAACCCAACCATCGCCCTGATTGATGGCGCCCGCGAGTTCCGCGGCATGCGCTTGCTCGATCTGGCGCGTGAGTGTGTAGAAACTGTCGGCGGCAATGCGCGCGGCATGCTTCCACAGGAAGTGGCGCGAGCAGCTCTCGGTTGTGACCGCACCGCCATGCGGGCCGCCGGCATGCAAACCACCAGCGACTTCCCGATCCTGCTCGGCGGTGGCGTCACTCGAACCCTTCGCGACGCATACGCCCAAGCTCCACAGACCTGGCGCCTGCTTGGGCAGCAGACCACTGTTCCCGACTTCCGTGCTACAACCCGGGCTGCCCTGGGTGATATCGCTGCACTGGAAGAGGTCAAAGAACACGGCGAGTACAAGTACGGCAAGCTCGAAGAAGAAGGCGCACCGATCCGCGTCACCAAATTCGGCAAGATCATTGCGATCACCTGGGAAGCGGTTATCAACGATGACTTGGGTGCACTCACCCGCATTCCTCGAGCGTATGGCCTGGCCGCAGCTGAGACTGAATCCAACCTGGTTTGGAACCTGATCCTCAGCAACCCTAACTTCACTGACAACAACCCGATCTATGTTGCTGCTCACGGCAACTTGGCTGCCAGTGGTGGCGCGATCAATACCACTACCCTGGGTGCCGCTCGCGCCGCAATGCGCAAGCAAAAATCCAAGGCTGGCGCCTTCCTCAATGTCGAGCCACGTTACTTGGTAGTCGGCCCTGACAAGGAGTTGGAAGCCTTTCAGTTCACCAGCTCTCAATATGTTCCGGCTAAGAACTCCGACATCAACGATGGTCGTAATACATCGCTGGTCGTCATCGTGGATGGCCGTATCACGGGTAACCAGTGGTACCTGTTCACTGAAGCCGGCCTCATTGACACCTTTGAATACGCCTATCTGGAAGGTGAGCCGGGCGTCTTCACCGAAACACGCGAAGGCTTCGAGGTCGACGGTATGGAAATCAAGGCGCGCCTGGTCTTCGGTGCGGCATGGATCGACTGGCGCGGGACGTACAAAAACCCAGGCGCTTAACCGCGTATACGCAGACCTAAAAGGGCGCCAGATGGCGCCATTTTAGTTTTCCAGTTTCAGTCTCGAAAGGGGACCTTGCATGAAGACTTTCATCCAGCGCGGCGACTGCCTCACCGTTATTGCACCGGCCGGGGGCACTGTCTCCGGTGAGCTTTATAAAGTTGGTTCGGTCATCGGCGTGGCAGCCACCACCGAAGTTGCCGGCGCGCCTGTGGTGCTCAAGCTCGAAGGTGTTTTTGGCCTGAACAAAATCAGCGCCCAAGCCTGGGCAGTGGGCGACCTGCTGTACATGAACACCACCTCCCGAGTGCTGACCAACGTCTCTGCCACCGGCCTGGTGCTGGTCGGCATGGCCACCGAGATTGCGGCCAACCCGAGCGCGACCGGTGCCTGCCGACTCAACGGCGTATCTGCTCCGGCACCGGTGTAATGGGCTGGGCCTCAATGGCCCAGCGCATGCTTGGCGTTTCGATCCGCACCTTCAGCGAACCTTCAGCGACCCTCGACCCTGAGGGCGCTGTGTACTGGCTGACTGATGGGGTAGAGCCTGGTGTGCCTCTGGCCCAAGCCGTGTTCGATACCGCACACATCTCCGTTGACCCCGAGACAGGTGCGCCGGTGTCGAGCCAAAACCCAATCCTTGGCATTCGCCTGGTCGATCTACCAAACAACCCAACAAACCGTGACCGGGTTCGAGCTCGCGGTGTGTTGTACATGATCAATGAACCGCAGTTCGATGGCGTGGCCGGCGTGACGATCCCCCTTCACGCCCTGAGCCTGTCCGTCAACCTGAGACTACCTCCATCGGCGCCTCTACCAACGTGGATCCACGCCCCGTCAAAGCCTGCAAGTAAGCCTTTTCGTCATAGTAGGTGCTGGTTTTCCAGCACCTATAGACGATTCTGATCCACTTGAAAGCGAGTGCTCTCAGGGTCGCCTGGTATGAGCAGCCTTTAGCCCGCTGCTGCCGATAATAAGCCTCGGCCCACGTTGATTGAGTGATGCTGTGAGCGGCCCATTCCACAAAGGTCTGACGCAAGAAGGTTGAGCATTGGTAGCGCCAATACACCACTGTCTTCTTGCCGCTACGCTGGGTCACGGGTGCGATTCCGGCATATCGCTGCATTGCATTGGCGTCGCTAAATCGATCACGCTGTTCACCAAAAGCCACCATCAGACGCGGTGCAAGATGTTGGCCGGCGCCAGGGAGTGCCTTGAAGATCGGGTAATCGGCCAAGCTGTTGGCCGTTTCTTGAATCTCGCGATCAAAATCCTTGAGGGTGCAAATGAGCCCTTTGAGTTGCGACGCCAAGGCTGTTGCGTACAACTGCGAAGGACGTATTACCCCCGGGTCCTGCGTCAAGGGCATCGCTTGGGTGATGATTTCCCAGCGCGTTTGATTGAGTTGAGCGTGACGAGCGTTGTGCTCGTTAAAGAACTTGAGAAAAGTACTCTGGCGAGAGCGCTTGAGGTGTTCAAGCGTGGGCCAGCGCATCAGAAAGTCACAGAACACCACGCTGTCATGATTGCTAAACAGCTCCAGGGCCGCTGGATAGTACTGTTTGAGCGTACAGATCAGGCGGTTGCTGACCTTTACTCGCTCATCAACCAGTGCCCGTCGATGTTCTGTCAGGCTGGCCAAAATACGCATCGCCGGGCTTTGCGGCATCAGCTGCGCAAACCGTTGGGGATAGGTGAGCAACAACTCAAGCGCCCATTGCGCATCGGTCGGATCATCCTTGGCACCGCTGCCGACAAAGGCTTTACGGTGTTTGGCCAAGGTACTCGGATTGATGGGGAACAGGCAAAAGAACTCGTACTTTTGCAGGGCCGCCACCAACGGGCCTTTGTTGAGCTCAAGAGCAATCGCAATCGGAGCGCCGTAGCGCTCAAATAACGATTTCGCCCAGCGATCAATCGACTGGGGCGTGTGGTCGATCACAGAGAAGTGCCGCCGGGATTCCCCCGCGACCTGCAAACACACGTCGTGCTTGGTATCGGCCCAATCTATTCCGACATAAGCAGTGAATCTCTGAGACAGGAGCGTTTGCATCAACAACCTCCACCGGCGCTAAAGTACATGCAGGGACATGCATGCTTGCGTCCAGCGAAAGCGATATAGAGAGCCGTGTCGGGCTTTCCCTGAGTATTCGTTAGAGGGCGCAAGCGCACCTGTGGGCTCGAAAGTGAAGGGGTAATCATCACGTGCTTGGGAGGCATATTCGTAGCCCACAGGTGCATGTTCCTTCCTTGATAAAACTGACTTCCAGACGCTGAAGTATGGAAGAAGAAAGGAACGGACAACCTATATCGGAAGGCATGACCATGGCACACCCAAGAGAAATGATCCGAAAGCAGGCCGTTGCGGTGCTGCTGGGCGCTACCAATGTCGGGGCAAGCGTTTATGCCAGCCGTGTGAGGCCGCTCATTTCCAACGGCTGGCAGAGCGAGCTCCCGGCGATCATCGTTTACACGATGGACGAGTCGGGCGAGATCTTTAATCAGGCGCCTCGCGAGTATCGGCGCCGCGTTGAGTTGGTGGTCGAGATCCACGCCGAAGGCAACGATGCGCTGGATGACACTCTTGATACGCTGGCCCGGCAGGTCGAGCGCTTGTTGCTCATGGACGACACCCTCGGCGACACCGCGAATGACCTGCAATACGTGCGTTCTCGCATGGTGCTGCTCGATCAGTCGGAGCAACTCACCGGCGCCTGCCGCCTGATCTTCGAGGCCGAGTACTTCGATCGTCACCCTGACGACCTGTTCAACCAGAGCTTGCCGGACCTGAACACGGTCACGACCGAGTACAGCCTGAGTAACGCGCAACCCAATCCGGCGGATCGTGCCAAAACGATCATCGAGGACCTGAACCCATGACAACGCAACAGCACGTTAAACCCGCCGTCGGCTGCCTGGTGCGCGACCCGGATACTTATGAGGCCCTGCCTGTGGAAGGCAAGCTGGTTGAAATGAACAGTTACTGGCTCCGCAAAGAAGCGGCCGGTGACATTGAAATCGTCGAGCCTGCCGTGCAGGACCTGAAACTCAAGGGTGACAAACAATGAGCATCGGATTTAACACAATCCCGGGCCCCGGCGCCCTGCACAAGCCAGGCGTGTACAGCGAGATTGATAACAGCCAGGCGGTGAGTGGCCCTCAGGCTGTGACTTATCGTCGTCTGCTGATCGGGCAAAAGCTCGTCGCCGGCCTCGCGCCTGCGGGCGCTTTGATCCGTATCACCAGCGCTGCACAAGCCGACACCCAGTTCGGTGCGGGGTCGATGCTGGCCGGCATGGTCCGTGCGGCCTTGGCCGTTGATAGCTACACCGAGCTGCAAGTCATGCCATTGGTCGATAATGCCGCCGGCGTTGCGGCGACCGGTACCCTGGTATTCACCGGTACCGCCACCGCGTCGGGCACCATTGAACTGATGATCGCTGGCCGGCGTGTCTCCGTTGGTGTGATCAGCGGCAACACTGCCGCGATCATTGCCACTGCCGTCGCCGCGGCCATCACGGCTGCCGCTGACATGCCGGTTACCGCTGCGGCCGCTACCGGCACGGTCACGCTCACCTGCCGTCATAAAGGCGAAGCTGGCAACAGCATCAACGCACGGGTGAATTACTACTCCGGTCAGGCTCTCCCTGCGGGGGTGACGCTTGTCATTACCGGGCTTGCCGGCGGCACCAGCAACCCTTCGCTGGCCACGGCACTCGCTGCTATCGGTGATGAGTGGTTCCACGCCTGGGGCGTCGCGTATTCCGATGCCGCTACGTTGGCCGAGCTCAAAGTAGAGTTGGATAGTCGCTTCGCGTGGGGTCGTGAGATTGAAGCGCATGCCTTTACGGCTGCACGCGGTACGCAGGGTACGCTCAGTGCTCTGGGGCGATCCCACAACAACGAACACCTGGTCATCGCGATGGCCAACGACGAGCCGATGCCGGCTTACGAAAAGGCCGCTGAAACGATGGCGATCGCTGCGTACTACGCGGCCATTGATCCAGCTCGCCCGATTCAGAACCTGCCTTACGTGTGGTGCCTGCCACCGGCAGCCGCCAATCGGTTGACCAACCAGGAGCGCAACCTGCTGCTGTTCGACGGCATCGCGACCACGAAGGTGAGCTCCGATGGCGTGATGCTCGCCGAGCGTTTGATCACCACCTACAAAACCAATGCAGCTGGCGCATCGGATATCAGTTACTTGGACAGCGAAACGCTGTTCACCCTGATGTACATCCGCCACGACTGGCGCGACTACATCCTGCGCAAGTACCCGCGCCACAAACTCGCCGACGACGGCACCCGTTACGGCATCGGCCAGGCGGTGGTCACCCCGGTCGTAATGAAGGCCGAAGCCATCGCCAAGTTCCGCGAGTGGGAGGATTTGGGCCTGGTCGAGAACATCGACGACTTCAAGGCCAATCTCATTGCCGAGCGCAATGCCAGTGACCCGAACCGGATGGATGTGCTCTTGCCGCCGGACCTGGTCAATCAACTGCGGATCGTCGCCAACAAAATTCAGTTCCGCCTGTAACGGCGGCAGCCAGGAGAAATAGAACATGGCAGGCAAAAACCGCATCGGCGGGATCATCGCCTTGAAGCTCAACGGCGACATGTACTTCGCCAAGGGCAACTTCACCTACAACCTCGGCAAGCCGAAGAAGGAAGGTGTGGTCGGTAGCGATCGCGTCCACGGCTACAAGGAAGTGCCGCAGGTTCCTTTCATTGAGGGCGAGATCACCGACCGCAATGAGTTGAATCTGGAAGACCTGGTCACCCTTGATGACGCCACTGCCACGCTGGAACTGGCGAACGGCAAGGTCATCATGCTGCGTGAAGCCTGGTACGCCGGCGAGGGCACCGGCAACACCGAAGAGGGCAACATTGCTCTTCGTCTCGAAGGCATGTCGGCTGAGGAGGTTCGCTAATGGCAAAGGAAAAAGTAATCCAGTTGGTCGAGCCTGCCGAGTTTGGCAAGCAATCCTTCACCGAGGTCACCGTCACCCGGAAGTTGAAGTACCTGCGTGGCCACGCGCTGCGCATTACTTCGGACGGTAAGGGCAGCGGCGGCGTCGACATGGACTTCGCCACCCTGATTGACCTCGCGGCCAAGATGGTTGGCCAGCCAACCGCCATGATCGAAGAGCTCAGCGAGGATGATCAGGCGGTCCTGATTCAAGAAGCCCGAGATTTTTTACTGAAGCACCTCGGGGGTGGGAGTCAGGAGTGACTGTCGTCGTCAAGGTGATGGGCGTTCAGCCCACGGAAGTCATGGAAATGGATTTCGAACAGCTGGACTGGTGGCTTGAACGCACTGAGGAATGGGTCGGATGGCAAACAAAGGATACTCCCTAGACGTCGTCATCAAGGCCGTCGACAAGCTCACCGCTCCATTGCGCGGCATGTTCTCCAAGGTTAAGCAAGCCAGTGCCGGTGTGACCGGCGCACTTGATCGTACTGGTCTGCCAGTGTTCGCGAACAGCCTTAAGGGTGTTGGTGGCGCTATTGGCGGAATAGGTACTGCCGTCAGTTCCAGCGCAAAGAAAATCCTGGGGTTAGGGGCGACACTGGGCATCACCGGTGCCGCCTTGAACTTGTTCTTCCAGGGTTTCGCTGATGCCACTGGCGCGATCGGCGACACCGCCGAGCGCACGGGTATCAGCCGCGAGCGGTTCCAGGAGCTAAGCTTCGCGGCGAAGCTGACGGGGTCGTCTGCCGAGACCTTGGGCGGTGCGCTGCAAAAAATGCAGATCAACGTCGGTAAGGCGACAGCAGGCTCGAAAGACCTGAAGGAGATGTTCAAGGGGCTGGGCATCAATATCAAAGACTCTTCAGGCAAACTGAAAAGTACCGATGCTTTGTTCGACACGTTCGTTAACCGAATCTCCAAGATCAAAGACCCGTCGTTGCAGGCGGAAGCAGCGGTGAAAATCTTCGGCAAGAGTGCTACTGAGCTGCTGCCACTGATTCGTGGCGGTGGCGCGGGTATCAAGGACATGGCGGACGAAGCTCGTCGCTTGGGTATCGTCATCTCCGATAGCGCCGTGCGCGAGGGCGAGACCTTCGGTGACACGCTGGACACGCTCCATACCGCTCTGAGCGGTGTTGGCAACTCAATAGGCAGTTCGCTGGTGCCACAACTGAACATTCTCGGTTCGAAGTTGATCGACAACATCGTCAAGTACCGACCGCAGATCGAGGCGTTCGCGACCAGCTTTGCTGAAAACTTGCCCGGCAACATCGAAAAGGTCACTGGCTTTATTAATGACCTTTACGACGGTATCCAACCAGTGATTAAGGTGATTGGCGAGCTAAGCGACACATTCGGCGGAGCAAACATCGTGTTAGCTGTGCTAGGTGCATACATCGGCGGCGGATTGCTTGTAAGCCTCGTGAGCCTGGTTGGAGCAATTAAGACTGTCGGTGTAGCTTTGCTGACAACACCTGTGGGTTGGTTCCTGCTAGCCGTTTTAGCGATTGGTGCAGCGGCGTACGTAATCTACAAAAACTGGGACGGCCTGGTCGCATTCTTCACGGAGAAATGGGCCGGCGTGAAAGCGGCGTTCAGCGACGGCATCATCAACGGTATTGTGAAGCTTTGGCTTGAGTACAACCCGGTCACTTTGATGATGGAGGCTTTTAACGGGCTGGTTCAATATCTGACCAGTTGGGACCTCAGTGCAATCATCGGGACCAAGTTCAGCGCTATTGTTAAGGTTTGGAACGAATACAATCCGGTCGCCTTGATACAGGTGGCGTTCAACGGGCTGGTTCAATACCTGACCAGCTGGGACCTCAGTGCAATCATTGGGGCCAAGTTCAACGCCATTGTTAAGGTTTGGAACGAATACAACCCGGTTACGTTGATGCAGGAGGCATTCAACGGGTTGGTCCAATTCCTCAGTGCCTGGGACCTTAGTGCAATCCTTGGAACCAAGTTCAGTGCCATCGTGAACGTTTGGCTCGAGCACAACCCGGTCAAGTTGATGATGGAGTCCTTCGGCGGGCTGATCAAATATCTGACCGGATGGGACCTGGGAGCAATCCTCGGTTCGAAAATATCGGATGCCGTCGCTGCGTTAAAAAACGGTTTACCCGATTGGGCGAAAAAGCTGCTGGGTATTGACGGTGCCTCGATGGGTGACGTGACGGGTGCTGATCCTGGAACCTCCAGCGTCGCCGCAGCCTTGGCCACCGATCCAAACGCCGCACTTGGGCCGCGCCGTTCAGTCACTGAGTTGGGCCAGCGCGCAGCTCAGGTTGGTCAGACCGCTGCGCAGGCAGTCGAACAGCCAGCGCAGAAAGTGTTGGTGCAAGTCGACATGAACAACCTGCCGCCAGGCACCAAGGTTAAAACCGAGGGCAGCCAGGGCGCGACGTTCGACACCGACCTCGGTTACTCAATGATGGCCCCCTAACCGGAGTTTTCCATGACTTGGCGAGACACCTACCGCGCCGCGACCTTTCGCGGCGTGGCCTTTTTTGTGGAAAGTGCGGACAGCAGCCACGGTCGGCGTCAAGCCGTCCACGAAACTGCACAGCGCGACACTCCGTACACCGAAGACCTGGGTCGGAAGTCCCGTGAGTTTTCGGTTGTCGGCTATCTGCTCGGTAAGGACTACCACCTAAACCGGGACGAATTGATCAAAGCCTGCGAGGTCGCCGGCCCGGGTGCTCTGGTTCACCCGTATCGCGGGGAAATGAACGTTGTTTGTCGCGGCCTGAACATCAGCGAGACCGCGGCTGAAGGTGGAAAGTGCACTATCGCACTCACATTTTTGGAAGCGGGGGAGGCGGCCTACCCATCGGCAAATGTTGATAGCGTCAATGCGATCAGCGCCAAGGGCAACACCGTCACCGCTGCAGCGGAATCAAGCTTTTTGTCTGACTTCCTGACCACAGGATTTCCCGCCTACGTGGCGGAATCTGCTGCGTCAGGGCTGGCAGGCCTTGGTGAGTACATGGCGGCGCCGGGCTTGAATTTCTCCGGTGACTTGAAGGCAGCATCTGACTTTTACCTGCAAGCGCGTGGGCTTGTTTCCGACGCTTCAAGTTTGGTCCAGAAGCCATTGAATATGGTCAGCCGTATCACCGGTTTGATCGGTTCGGTTCGCTCCGCTTTTGGAGCAAACGCTTTCAGCATGCTGACCAGTTTGTTTGACCGTTCGCCGAGGACCTATACAGGCAGTACCGCAACGCCAAGCCGCCAGCAGCAGGCCACCAATGCAATTGCGATGAATGCACTGGTGCGCCAGGTGGCTGTAGCCGAGGCCGCCAAGGCTGCGGTCGTTACGCAAACCCCGGTGGTTACGACGACGGCTGTCACGCAGGCATCGACAGGAGTACCTCGGACGGCACTGGGTATTCCGCAGGGATCGAAAAGAGCAACGCAGACGGCGCCTGGTGTTACGCAAACGCTCCCTGTTCCAACCGTTTACGACAGCTATCAGGCAGCAATCAAAGTCCGAGAGGATCTGGTCGACCGTATAGACGCCGAAAGCGAAGTCACGCCGAACGATGAAGTGTACGTCGCACTGTCTGATTTGCGTACCAGTGTGGTTCAGGCCGTGCCCAACCCGGAACAAAACCTTGCCCGGATTGTTCAGTACGTGCCGCGTGAAACGCTGCCTTCCTTGCTGGTGGCTTATCAGATCTACGGCGACGCCGGACGCGCCGATGACATCTCGAACCGCAATTCAGCGCGACACCCGGGTTTTTTAATGGGCGGACAACAGCTCGAGGTACTCGCAGATGGATGACTTGGAGCTGTTGGTCAACGGTATGAAGTACGCCGGCTGGACTTCTCTTGGTGTCACCCGTGCGATCGATGCGGCAACCACGGCCTTCACGGCATCGCTCACCGAAAAATGGGAGGCGGGAAACCGATCGCTGGCACAAGTAGAGCCCTGGCCGATTCTCCCGGGTGATGCGTGCGAGGTCAGGCTAGCCGGCTTTCCGATGGTGATCGGCTACGTGGATATTTTCAAACCGTCCTACAGTGCGAACGACCACACGATCAACGTGCAGGGCCGGGATAAGGTTGCCGACCTGGTGGATTGCAGCGCGGTGCACGCGCCGGATGAATGGAAAAACATCGACCTGCTCAAGTTTGCGCAGATCCTCGCTGCTCCGTTCGGGGTGACGGTGAAGGCGGATATAGCCGTTGGTGAGCCGTTTCAGGTCTGCAAGCTTCAACAGGGCGAAACAGCCTTCAAAGCGATTGAGCGCTACGCCCGGCAACGCAAGGCGCTGTTAATGCCTGACGGCGCTGGCGGGTTGTTGATTACCCGTGCAGGCGTTCGGCGCGCCACAACTGCTCTGGTGCAGGGTGAAAACATCCTCAATGCCAGCGGCACCATTGATCACAGCCAGCGGTTCAGCAACTACCAGGTGAAAGGTCAGGCAAGTTACAGCCCCGACAGCACCGGAGAAACCGAGGCTCACATCGAAGGCAGCGTTACCGACAGCGGCATCAAACGTTATCGACCAATGCTACTGGTCGCCGAGATCGGCGGCACAACTGCAAGCCTGCAGGATCGCGCCACGTGGGAGGCGAACAGCCGAATTGGCAAGTCCGCTGCTGCCAGCGTTTCAGTCTATGGATGGCGGCAAAGCCCAGGCGGAGCGCTGTGGGAACCCGGCATGCTGGTCTACGTCCGATCGTCCTGGCTTCGCATGGATGGTTGGATGCTAATCCGCCAAGTCACTTACGAGCGCGGCGAAGGCGGGACCACGGCCAAGCTTGAGATCGTCAGCCCGCAGGCCTTCGACCCAGAGCCACCCGACGGTAAGAAAGCGAAAAAAACAAAGGCCGGCAAAAAGGGTCAGCGCAACATTTGGGCTGAAGCCATCGGCGAAGAGGATCCACCGAAATGAGGGAAGCGCTCCGCGAGATTGGCAGCCGCGTAATGATGATGTTCTCCCGTGGCGTGCTGCGGGGCGTCAATGATTCCGGCCCCAGGCAACAGGTGCAGGTTGAGTTGCTCAAGGATGAACTCCGCGATGGGCTTGAGCACATGCAGAACTACGGATTCACCAGTCACCCGAAAGGCGGTGATGTTGCGGTCGCTTTTCTGGGGGGCAACCGGGAGCAGGGGATTGTCCTGGTTGTCGATGACCGCCGGTACCGCATCCCTCTGCTCGCCGGTGAGGTGGCCATCTACGACGACTTGGGCAACAAGATCGAGTTGCTGCGCGAGATGGTGAAGGTGACGGCTGTTCAGCACCTGGAAGCAGTGGCGCCGACGATCAAGCTGGTGGGCGATCTTGAAGTGATCGGCAACATCACCAGCACCGGCACCATCAAGAACAACGGTAAGGACATCGGTAGCACCCATAAACACAACGGGGTTACTGCCGGTAGTGGAACCTCAGGAGTGCCGATCTGATGGCTGATGCCGCAATGGTAATGACTGAAAACGGCGGAGAGCTGTTGTTGTCGGGCTTCGATTTGGCGCGAGATGACGGCCTAGAGACGGCAGTCATCATCAGCCTCTTCACCGATCGCCGGGCTAGCGCCGAGCAGCTCCCCGTGGAGCTGCCGCAGGATGATCTGCGTGGTTACTGGGGCGATATCGGTAACGCCACACCGTCGGACCAGACCGGGTCGCTGCTCTGGCTGCTGGCGCGAGAAAAGCAACTTCCGCAGATCCTTGGGCGTGCTCAGCAGTATTGCCGGGAGGCATTGGCCTGGATGGTGGAGGACCTGGTAGCAACTCGCGTTGAGGTGAAAGCGGAGTTCGTTGCCCAAGGCTGGATGCTGATTCTCGTCGATATTTTCCGACCGACCGGTTCGCCGGTTCGCTATCGCTTCAATTACGAATGGGCGGCTCAAGCCGCGAAGAGGCCTGCCTGATGCCATTTGCTCGACCAACACTCACCGAGCTCATTGACCGCGTGATCACCGACATCAGCAGTCGGGTGACCGGCGTCGACAGTGCGGTGCTTCGGCGATCGCTGCTCGGGGTCATCGGCCAGTCCGAAGCCGGGGCTGTGCATATGCTGTACGGCCACCTGGACTGGATCGCCAAGCAATCGGTTATCGACACCGCTGATACGGAATACCTCGAACGTTGGGCTGCCATCTGGAAAGTCGTTCGCAAGACTGCCGGTTTTGCCAGTGGTTCGGTTGCCTTTTCCGGTACTGCCGGTTCCACCATTCTCGATGGGACCATTGTGCAGCGCCAAGACGGAGTCCAGTACAAGGTGCTCGGTGACGCCGTATTCGGCAGTGGGCCATTGGTAGTGCCGGTTCTGGCGCTGGAGGCTGGTGAAGCCGGCAATTTTGGCTCAGGGTTGCCGATCTTCCTGTTGTCACCGATCGCTGGCATCCAGTCGACAGGGACAACAGCAACCAAGATCGAGAACGGTGTCGACACGGAGTCGGATCAACGGCTGTTGGCCAGGTTGCTGGCGCGAATTCAGCAGCCTCCACACGGCGGCGCAGATTTTGATTACCAGATGTGGGCTTTGGAAGTGGCCGGTGTCACCCGGGTCTGGGTATACCCGCGCCAGATGGGCGCCGGCACTGTAACGGTCCTGTTCGTCTGTGATGACCTTCCGGACATCATTGCAACACCGGCCAAGGTGGCGGAGGTGCAGGCCTATATCAACGCCCGTGCGCCAGTGACTGCCGAGGTCTTTGTCGCAGCGCCAATCGCCGATTCCTTGAACCTGACGATCAAGCTCACACCGAACACTACAACCGTTCAAAACGCTGTCCGCGCGGAATTGACGGATCTCATCGACCGCGACTCCGCACCTGGTGGGACGATCCTGATCAGCCGCCTACGCGAAGCCGTGTCGCTTGCCGCCGGCGAGAACAACAACCAGATCGTCACACCAACTGCTGACGTGGCGCACGCCACCGGCCATATGCCAATTCTAGGCACCCTTACTTTCTCCAGCTTCTAGGAGGCGCAATGTCGACAGCTGCTGAATACAGGGAGCAGCTTAAAGCGCTGCTTCCACCTGGACAGGCATTCCCCCGCGACCCTGGTACCACACTGCACGATCTTCTTGATGGGATGTCGCTCGAGCTGGCTCGTGTTGATGACCGTGCCAGCGCGCTACCGCAAGAAGTGAATCCGAATACGACCTTGGAATTGCTCCCAGACTGGGAACGCGTGGCGGGTCTTCCAGACAAATGTTCGGGAACCCTTGAGGAAACGTTGCAGGGACGGCGCAACGCCTTGCTGGCAAAACTTACCAGCACCGGCGGGCAATCGGCGGATTACTTCATTCAGCTTGCAGCATCCCTTGGATACGCCGTGACGATCGAAGTGTTCCGCCCATTTCGCGCGGGCAGCTCCGTCGCAGGCGATGTATTGAGCAATGGCGACTGGGTCTTCGCCTGGCGTATACATGCCCCGGATGTGACGGTGATTCCCTTTCGGGCCGGCCTTTCTGTTACCGGTGAGCGTCTGCGTGTTTGGGGCAGCGACACTCTCGAGTGCAAGATCCGTCAGCTGGCACCGGCGCATACCATCCCGATCTTCGCCTATGGCGACGCCACGCTCGACCTCAACTTCGTGCAGGACACCTATCGGTCAGGCGCAAATAACACAACTTTCGCTGGCCTGATCACGTTCACGCGGTCGACGACTGCCGGGCGTTTCAACGCAGCAGGCCTGTTCGAGATGGTACCGATCAATCAGCCCCGGTTCGATTACGACCCGCTGACGTTGGCACCTAAAGGTCTGCTAATGGAGGAGGCGCGTACAAACCTACTGCGGTTTAGTGCTCAGTTCGATAACGCCGCGTGGATCAAGTTTGAGACAACGGTATCGGCCAATGCTACGGCCGCGCCTGACGGCACTTTAACTGCAGACAAGATGGTGGAAAGTACAAATACGACCTCTCACACTGCGGACCAGCAGATTAACGGGACCTACACCGCCGGGCAGGTTTTCTGCGCGTCGTGCTTTCTAAAGGCCGGAGAGCGGTCATCCATCCGGATGAACCTGTATTACGCCGTGGGTAGCACTGGCGGGCGACAGATTGTTTTCAACCTTGCCACAAAGTCCATCACCTCGAAGGATCCGGCCATTCCGACTGCTGGGGTGGAGGACGTAGGCAACGGATGGCTACGCTGCTGGTTTACTGGCGTCGTGGATACTCCTGCGGAGACGCGACTGCTAATGCGCGTCCAACTGGCCATCGGAACCACGACAACCTATGCCGGGGACGGGACTTCGGGAGCATATTTTTGGGGGGCGGACATTCAGGAGAGTGCATCACTGCTTTCCCATATCCCGACAACTACTGTACCGGTTACGCGCTCTGCCGATGTAGCGGCGGTGAACACGCTGACGCCTTGGTTCAGCCCGGCACGCGGCACCCTCTATTCCGAAGCGACAAACGTTGGCCCGTCGGGTACCACCATTGCTCAGCTGGGCAGTCTTTCTGATCGAATCCTGACGTCGGTAGCGCCTTCGGGAATAGCGGGGACTGGCGGAGCGACGATTGTCGGCTCGGTGAACCAAGCGAGCATGCAGTCAGCAGTGGGCGCTCCAGGGCAGAAAGTCGCCTTCGCCTACTCCACAGATGACTTCGCCTGCGCCACCAACGGGGTTCTTATCGGGACGGATACGTCTGGCTCACTGCCTAGCGTGTCATCCCTGTTGTTGGGTCGGAATGGGGCATCAACGACCAACTGCCACATCCGCCAGATCACCTACTCACCGAAACGGCTCAGCAACGAACGCCTGCAGGCTATGACTGCGCCTTGACCATCCACTACGGAGAACAACCATGCATCGTATCGACGGCCCTGGTGCCACGGTAGACAAAAAGTTTACAGAGGGCGACCCCACGGGAGGGGTGCAGGCCACGGTATTAACTGACGATTGGCTCAACGACGTGCAGGAGGAGCTTATTACGCTGCTCACAGTCGCTGGAATCACGCCGGTTAAGGGCACGCAAAATCAGATTCTTGCAGCTATTCGCAATCTGAAGGGCGTACAACGATTCACTGCGAGTGGTTCTTTTACTGTGCCGCCTGGCGTGACCACTATTTATACCTCTGGCGTAGCCGCGGGCGGCGGCGGTGGCGGTGGGGGGAGCAGCAATACGGCGGGAGCTGCGGCTTCTAACGGCGGTGGTGGCGGTGCGGGTCAGTCCACTCAGCGCACCCCACAAACAGTTACTCCGGGGCAGGTCATCGCTATTACTGTCGGTGCGGCAGGTGCAGCCGGAGGTGGGGGAGGTCAAGGCTTTGACAACGCCACTGATGGCGGAGCGGGCGGCAACACTGTGATCGGGTCATTAATAACCCTCATTGGAGGTAGCGGTGGCGGCCGAGGTCGTGCCGCTACTGCAGGTGGTCCGGTAGGTGGCGGCGCAGGCGGTACAGGCTACCCTAACGGCGGTTCAGGTACTGATGGTGCTGGTTCTAGCGCAGCTACTGCAAACGGTTGGCCAGCCACCTCCGGTGCAGGTGGTAGTGCGCCTTTTGGTGGTGGCGGCCCTCCACAACGCTCCGGAAACTCTGGCGGTAATCCTGGCATTCCTGGGAATTTTGGTGGCGGCGGCTCGGGCGGTACCGGTCCATACAACTCCGGCGGGGCCGGCGGGGTCGGCGGTCAAGGTGGTCAAGGCATCGTAATCATTGAATGGTGAGTGTTATGGATCGATATGCTCTGATTGAGCTTTCTACTGAACTGGTCGTAAACGTTGCCATCTGGGACGGAGAAACGGAATGGGCGCCTGAAGAAGGCGTCATCGCTATCCAATCGGATTCTGCTCAGATTGGACACAGCTATGTCAAAGGTGAATTTATCGCGCCTCCGGCGCCAGAAGATCCCCCGCTGACACCTGAAGAAATTCTTGCCGTTAACGAAAAGACGAAGGTCAATCTGATGGCGCAGGCATCACAGGCAATGACCCCATTGCTTGTATCCCTTCAACTGGGTAATGCGACGGACGCTGAAACTACTTCAGCCCAAGCCTGGCAGGCGTACTGTCGAGCTCTGAATTTGGCTGATCTCACTATTGAGAGTCCTGCCTGGCCAGTTGTGCCTACGTGAGGTCGTAGTCGTTGAGTAGTTTCAGATACGGTCATGAAGTCATCAGGGGGTCTGGATTGGCGCTGGCAGGTCTACTTCCGAGCGAGCAGAATCGCGAACTCGATTTCTGATCTTATTGATTGGCTGGTCGACAAACTTGACGATCAGGGCGCTTGCGAGGATGGTCACCGGGTATGCGATTGCAAAAATCACCCACCCTCGTTGTTCGCCACCGAACAGCCTCCAAACAAAAAATGCATAAATAAAATGACCAAGAAACATTGGATAAGCCAAGTCGCCCAGGTATTTATCGATTCGTCCAATTAATCCTGTCATTCGAGCTTTGTTCACAACTACAACTGTCGCGAAGGCCAGAGCCATATTTGCATAGTAAGACCAGTGGTTGACAATCAAAGTGCTAGTTGTGATTGAGTAATACCAGATTGCCGTAAAGGTTATGAGACATGATGCGAATATCGATGCCTGAAGTTTTTGGTTTTGGCTTATTTGCCTAAGAATTTCGGAGTGCCTTGAGATAAAATAAGCTATTGCCCCTAGTGAGAAAGGTAGCATTGCAGCGGGGACAGGGAAATATTTTAAAAGTTGATCTGTAACGTAGTATGTTATGTAGATGTACCAGATGGCAGCGAGTGCGGCAGTTGTCATTGCTGTTTTTATGTTTCTGGCCGTGAAGAGCACTAGTATAGCGTAGCAACATAGCTCGACACCTACAGACCAAGAAGATGGTATTACCCGAAATTGATGAATTGTAGTGCCAGACACTAATCCCCATGGGAATATCAGGGCATTCCCGAGTATATCTAAGGGCGATCCTGTTATCGTCCAAACGTGATGGAATGATTTGAAGGACTCAGAGAGGGATATGCCCAATCCTACGGCTAGTGTCACAAGGTAGGCGGGATAAAGCCTGAGTACTCTGTTTTCAGTGAATGCTTTGACTTGGAATTTGTACGTCTCATTTAGTACGAGAGTTATTAGGTATCCGCTGATAGCGTAAAAAAACACTACTGCCAGCATTCCGATATTTGGAACGGACTCAGTCAAATGGAATAGCACCACACAGCTAGCCATGAAAAACCTGAGCGTGCCCATCATCTGAGTATGATCCATTTAAATTCAAATCAAAGAATTATGCCCATTGGAGACTGTTATGCCAATAACAAAGCAGCAGCTGCTGCAAATCCTCCCGAACGCCGGCAAACAAGCCGGCGTTTTTGCGTCTGCGCTGAACCTGGCCATGGACCGCTTTCAGATCAATACCCGGATGAGGGTGGCAGCCTTCATCGCCCAGGTCGGGCATGAGTCGGGCCAGTTCCGATATGTGCGCGAACTTGGCGGTGACCAGTACCTGAGCAAGTACGATACCGGTCCGCTGGCCAAGCGACTGGGCAATACGCCCGAGGCAGATGGGGACGGCCAGACGTACCGCGGGCGCGGCCTGATTCAGATCACCGGGCACGACAACTATCTGGCTTGCAGCAAGGCGCTGTTCTCAGATGATCGGTTGCTGCGAACACCGGAGTTGCTCGAGCAGGCCGAGTGGGCGGCGAAGTCGGCGGCGTGGTTTTGGCATTCACGCAACCTTAACGCTCTGGCCGATGCAGGCGACTTCGTAGGTGTCACCCGGCGCATCAATGGCGGTACGAATGGAATGGTCGAGCGCCATTCGTTCTACAGCACGGCGCTGAAGGTACTGGCATGAGGGCGATGCTGAGGATCCTTCCCTATATAGCTGCGGTGCTGCTGGTGGCGGCCGTGCTGTTCGGCGTCTATCACCACGGCGTGACCGTCACGGATGAGAAGTGGCAGTCCGAATGGAACAGCCGCGACACCCATGACGCAGCGGCGAGGGCGCTCAATGAGGCAGCTGAGCGCACCAAAGAGCAGGCCTACCAACAATCAATCAACAAGGCGGTTCAAGATGGCCAACGCATCATCGATCAAGCGACGGCTGATGCTGCTGCCGCTCGCACTTCTGCTGACAGCCTGCGCGGGGCAGCCGACGCCCTTGCCAACCGACTCGCAGCCAGTGAAGCCAGCGGCGATTCCTGCACTGCCGCCGCAGGCCAGGCAACTGCCCACTTCGCAATGGTGCTTGCCGACGTGTTCAAGCGCGCTGACGAAAGAGCGGGCGAACTGGCTGCAATTGCTGACCAAGCCAGAGCCCGGGGAGCGGCTTGCGAGATGGCTTATGACGGAGTTGCCAACGGATCGATCAGCGCAGGGCCCTGATTGCGCACGTTGCCGACGGCACGGTCCACCTTGAACCACTCGAACGCCTCCGTTGGCTCTCCCTGATGCATCACCATCTGTTCGGCGCGTTCTTTCGGCGTGGCCGGGTCGAGCCATTCCCGGGCGAGCTCTGGCGATAGCGTCACAGGCCGTCGGTCGTGGATATCGACCATCCCACCGGCGCTGTCGGCGGTGATTATCACGAAGCCATCGTGCACGCTTGGCTCATGCTCGGCGTTCGGGTATTGGCCGATCGCTGCGCACAGGATTGGCGACCGGTCGCGCCGGCGGATGAGGTAGGGCTGCTTTTTCGGTCCGCCTTCATCCACCCATTCAAACCAGTTGTTGATGGCGATGATTGCCCGGTGCGGCCAGATGTCACGGAAGAACGGGCCGTGGGCGACTTTCTCCACTCGGGCATTGATCGGTGCGACGCGGTCCTTGGCCCAATGCGGGCGCCATCCCCAACGAACCATGTCAGCGTGTAGATATTCGCCTTCCTGGTGAAAAATGGCGAGCTGGGTTGTCGGGGCAGCGTTGTAACGCTCGAACGGCCGGTCACCAGTGTTGTTCACCAGAGGGTTGGGCATGCTGAGTGCCGCCACGAAGTCGTGAATGCCATCGTATTGGGAAAGTCGTCCGCACATGTTCAGCTCCTCTGAATGCCAGCTTGCAGCTCGCAAATGATCCTTTCTTTTTGATCAAGAACCAGTGTCAGGCTTCGGATCTTGAAAAGCTGGTCGGTGGTTTCTGCCTCCAGGTTCGCCATCCATGCCAGCTTCTTTTGGAGTTCGGTCGACAGCTGGTCGTTCATTTCCACCAACGTGGAAATATTTTCCTTTGCCGCCTGCAGCTGACGCTTTAGATCCTGGACGTCTTCCTCAAGCATGCTTGCGTAATGCGTCACGGTTTCTAGCCTGGTCGGGCTGCCGAGCCATTCGCCGGTGTCTTCGATTTCGTAGGGGTCCACGGTTACGCCTTACGGGTACTGTTTGGATATACAGTAAACGAGACGGGGCGCTATGGCGAATGCTGGCGACGGAATGCAAATCAGTCCGGGGTCATCAGCACGGCGAGGGTTAACTTGATGAACTCTTCATTTTTGTCGATCGTGTCCAGGGCGCCACGCACGTTATCGGCGACGTCGGCCGCGCCGCGCTGCTCAACCCACTTAGAAAGCTCTAAGATGGCGGCTTCGAGCGCCAGTTGGTTTTCGTTGATCTTGAAAAGCAGCGAAGGCAGTAGATCAGAATTGGACATCGTGAACTCCCCGAAAAGATTTCAGCGTAGCACTGAACGGCGCTGATATTCGGTCGACGAAGGCGGATGTTGACGCCGCAACTAAAACGTAAACGTCCAGGTGATGTTTGGCGAATGATTTACTCGACCTTTCTGTGCGTCGTAGTCGGATCGCAGGATAATGATCAGTATGCGCTTACACATAATGTCGAGTTATGCTTAGAGTGTGTTATGGAAGTGTTCTTAGAGCAAATAGTGTGACGATATGAGTTCGCCAATCTTGATGAGGTGGGACTTGTCCTGTATCGTTACTGCAGGTCTTGAGTGGCGGGCTCCTTCTGGCCAAACTCTCCCGTATAATCTATCTCGCAGTTCTATTTCGGGCATGAGCTCTTCGTTCATTTCATGCGTGGAAGATCCGATTATGGAGAATAAAGCATGGCCTATGTTTATTGTTGTTATGTGGAATGAACTCTCAGGCTTTCCTGGGAGACCTGCTCTGTAATATCTAAAATATGTATTCTGGTTAAACGCGGTGTGGCAATACCATACGTAAGTGAGTGGTGGTGGCTTCAGTTGTGTCTTCATTATTGCATAATGGTCGATTGGAAAGCCGGGTAGATTATCACGATGCTTCAAAGCATTTACTGCAGCGGTCTTTGCTGCCCAGAAAGCTAATGTTTCTAAATTATCGTCGCTAGGGAAATTGCGTCGCGCATAAAATAGCTCAACAAGGCTTGATTCTGCATGATTCTCTAGAGTGTTCATCCATCCAGCATTGCACTCATTGCAAACGGAGTTTACCGTGCTGTCAAAAGGGCCGTGAGGAATAACAATTGGCTTTATATTAAAGCCGCCGTCTGATCTCCGAGTTTTGTTTTCCCAAGTAATGTGACTTGGCGTTTCCGGGAATAGTGAATTGAATTTATCCCTCAGAATATGTTCTTTTGTGAAATGTATGTCTGGGTGGGACTTGCTGCAAAACGGGCAGGCCTTCTTGAGTTTCATATTTTATTTCTCAGTGGGGTAGAGTTGTAAAATTTAGATTTTTTCCGCCAGTGATATACGATGATCGTATCATGGTTATATATTAGGGTTGAAGTGCACACTGCCAAGCTTGATATAAGCGTTACTGTCATGCAGCGCCAGGCAGGCACCAGACAGTAATTGCAGGGAGAGGATAAGGCCCATACCAATTCTTTTTCCTTATTTTTTATCGATGGTGTCTCAAAATCCGCGCACGTTGTTAGCGACCTCTGCCGCACCGTGATGCTCACCCCAGTTCGAAAACTCCAAAATGGCAGCTTCTAGGACGAACTGGTTTTCATTGATCTTAAAGAGCAGGGAAGGGAGCAGGTCTGAGTTTGGCATTACGAATCCTCCGTGAAGAGGTGAGCGTAGCATCATAAGGTGCGGGTGGATGCCGGGTAGGAAGGCTCAGAAAAAGCAAAGCCCCGAAGGTTCGCGGCTCCGGGGCTTCTATTTTCACCCGCATCCCTTAATGCCTGGCGAACGTGGCGGCGAGAATACCAGCGTTGAATCGGGGACTCACTATTGCGATAGGTGGTTTGTGTTCAGTCGGCAGAACGCCGTAAGGGTTGTGCGCAAAACCTCCTCTGGAGGCCGCGTGTTTCCGTTTGCATAAGCACAAAAAAGAGGATGTTTTGCCGCTACCGGAGAGGGCAGTTAGCCTTATAAAACAAGCACTTAGATCGCTTTAGTCCCCAGCATGGGGTGCTAGGGGTCGAGTGTTCGAATCACTCCGTCCCGACCATATAATTCAATGACTTAGCCCAACTTTCGCGAGTTGGGCTTTTTCATGTGCAGGGACTTTTGCGGGGGTTCATCCCGTTTTCCTCCTCAAGATTGTCAGAGCCGGTCCTCTCGAATCGGTCGCTGATACTTTGTTTGCCGCCTCAATCAACTGCTCGAGCTCTGCGGTAGAATAGTGGCTCGTAACGCTGCCATTCTTGTGCCCCAGAAGCGCCTTCCGATCCTCCAGTGTCACGCCCGCTGCACGTAGCCTTCTGCCAAAGGTGTGCTTGAGGTCGTGAATCCTGATCGATCTGAACCCGGGGTGTGCCGGTGACTTGTGCTCCACTTCCCACTTCGCCGCCGCTCGCACCCTGGCCTTCTTCCACGCTGTGTCATTCATCCGGTGCATCGGGGTCGGACCGTGTTCGTCCGGCTGCCCATACGGGAAGACATACTTCGAATGCAGCCCGCGCTGCCCGTCGATGACCGACATCGCCACCTTGTTCAGCACCACCAGCCTCTCGTCGCCATTCTTCACGCCAGACTTCTCATGCCTCCCGCCAAAGTCAGCAGGGATCAGGAATACACTCGCTCCCAGTTCCGGCACTCGGATTTCCCAATCCCACTGAAGCTTGCAGACTTCCTGCTCCCTGCAGCCCGTGTTCACTTTGTAGAGCGACATCCTCAACAGGTGGTCAGGTATTTCCGAGAACAGCATCGACTGCTCTGCCCATGACATGGGGTAGGGCTTCCTGCTCGACTTCCTCTCCTCCAGCATCGAGATCATCGGCACGCTATCCAGCCACGGCCGTTTCTCTGCGTCTCGCCACTTCCTGTGGCACAGGTTCAAGATTCGAACGACGCGCTGCAAGGCGATGTTCACCGTCCGGTTCGACACGCCTGGCTTTACCTTCCCTTTTTCAGTTTTGGCTGGCTTCTGCCGGTCCCGCTTGAACGTGGCCAGCGTCCCGTCATCTATGTGGGTGATCGGTAAATCGCCGATGTACGGGTCCAACTGCTCAATGTGCGAGGCCGAAAGGCCAATTGAGGCCTGGTCTTTGAACTCCACCAGAAACCTGGTGGCCGCCTCACGCCAGGTTCGCACCTGGCGCACACCGTAAACCTTTTCCTGCCTGAGCTTTTCCAAACGGTGGATCAGGTACTGCTCCGCTTCCTGCCTTTCGCTTGCTCCAGTGCTTTCTTGAAGTCGCTGACCTCGGACGACTTTGTCGATGTGCCAAATTCCGTTCCTCTCGTAGAGGCCGGAGATTGTTTTTCGCGCCATTTATTGACTCCTTGGCGCCCACTGCGGGGCTGATTGTTGTCCTGATTGGCGGCCTTTTCAATTGCCATGGCTTCGATATAGGCATCCGCCCACTGGTCGAGCTCTATCCGGTCGAAGCCAATACCCTGTTTCCCGATCGGGAATTCGCGCACGTTGGGCCGGACGGTTTTGTTGAATTCATCTCTGCACATGCCGAGATAGCCGTAAGCCTCGCCGGCGCGAATGAAGCGCGGAAGGATGGGCACGACCTGGGCCGCGCTGCGATTGGACATAGCGAATCCTCGCCCGCCGTCGCCGGCAGGCTGGTAAGTGGGAAAGGGTGAGTTGTCATTTTGTTTCTGAGTTACAGTCTGCGATGCGGCTCAGATGGAGCTCGTAGACGAAATCAAGGAGATGGGAATGGATTCAAAAGAAGGTGCTGCAATAATTGACGCATTGGCTGAAAGCATTCGAAGCAACCCTGGTCAATTTGTAATCCAATTGAAGGTGGTTGGTCAGAGCTTTGTCACGAATGGGGGTATCGGGGCGGTGATTAGCGCCACCGGTGGAGCGGCGGGATCGACGACGATTGGTAACCAAGTCCGAGTTGATGGTTCATCTGTAGACATTGCTCAAGGTGTCGCTGACAAAGCTGTTGTCGCCCAAATGAATGGTTTGGCTGAGGGGCTGGCGGAAATTTCTCGCCAGCTGACGAGCGCGAATCCGAATAAGGGATTGGTTGCAGAGATCCTTGATTCATTCAAAAATTCCTGGGTGCCTACAGCAATTACTGCTGTTGTTTCTACGGTTACCACGGGACTCTTGGGCGTTTAAATTAAGTTTGCGAGCCTGCGTTAGCGTAGTGCTCGCCTTTGGCTTCATCACCGCGGCCCCTTGTAGCAGTACACGTAGGCGAACAAGGCGAGGGCGATCATGGCGTCACCTTCTTGAACTCGACGACCCACACCCATGGATTGGCGGCCCAGTCGCCGCCGACGGATTCCCAAATATCGCGGAAGGCCTCCTTGCGGGTGGGCCAAGGCGTCACGTACCGACCTGGACCTTCTCTGCCGACCAGCGCACCACTGTCGTCACGCATAGCCCGCACACCTTCAGCCGCGCATTGCTCTTCGCTGATGTCCTGCAACCGCTCGACTCGGACGGCGGTGATCTCTAGCAGGATGCGGCTGTCGCGGCGGAACATGTGGATGCCCGGCTTCCAAGGACCGCCGTAGTCCGTGCGGTTATCGCTCTCGCGATACACCACCCATTCTTGATCCGGGGCCTGAGCAATACCAATTCGCGCCCAAGTTTCACGCACCCACAGCCGTTCGCCTGGTTGGCCAAACGGACTGTTGTCGCGGACCTCGACGGGGCCAATTTCGTTGCCGGCCAGCCAGCGGCCGGTTGCCTTGTCTTTGAGCGGGAACTTCACTGCACGCCGAGTGACCGTCTTCCGGCCTTCCACGATGGCGCGCACCATCGGGGCCGAGAACAGGATTGGCCGTTCTTTTACCTGGCTCATGGCGTCACCTCGCGACGTGCCCACTGCACATACGGGCCATTATCAGTGTCGAAAATGCCGAGCAGGAACCAGCCATCATCGGGCGGCGGCTCTAGTTCCCAGCCGAGGCAGTGGCAGGCTTCATCATCCCAGTAGGGATGGGCTTCCAAATCGGATTCCATGTGCCAGCCGATCACCTTCAGACCCTGGGTTTCGAGCCACGCTTTCCATGCTTCGGCGTCTTCATCGAATTCGGGGATATCCGGGTGATACCAATACCCGTCCGCGTCGCGCGTGACTTCTACCGGGCCAATCAACTTTTCTGCAGGCATGACTTCGTCCTTGCCGCTATAGCGGCTGACTTTGAAGGGGGAGGGAGTTCTATTGGAAGTGTATAAAATGAAAGGCCTGAATTTAGACCCGCCAAGAAAACGTATTACTTTTACTCCATCCTAGATACTTTGGCGGGTAGGCTCCATCTTCTATCATTAACAAAATCAGAGCTAAAGGTGGCTAGCTCTATTGCAGTTGTTAGCAGCCTCCGAGTTTGGGTTCCTCAATAAAGTTAGCTGTCATTTCTGGGAGGCTTTGGAAGTTGTATTGGTCATAAACTATCTGCGCAAGTGCTTTTGCTTCTTCATAGGTGCTGACATGCACGTTTTTTGAAAAGACAACATATCGATGTCCATCAGGGGAGGAGCGGGAAAGTCTAATGCACCAAGTCTGATCCCCCGCCACCCATCTATAAAGCGGCACAGTTCCATCGGAGCCAAGTGGAAATACGTAGCACGAAATTCCTTCTGCCACATATCCTGAGGCCGGACCAAGCTCACCATCCTTATCTAGGGTGTATAAGTGATCACCCGTGTTGGGGTTATACCAGCGGTAGAGAGGAATTGTTCCGGGAACGCCTGGGTTAGGTACATAGCATTCAATTTTTTCAAAGACATATCCCGCGGCTGGCGCTGCTTCTCCGTTAGGGTCGGTGGTGTAAAAATGCAGATTACTTTCAGGGTGTCGCCAGCGATTGAAAGCCGAAGCGTCTTCAGTTTGGTGATTTAGTACATTGGCTGTGATGCCTTCAGAAACATAGCCGGCAGCAGGTTCAGTAGTACTAGTGGTATAGAAGTGCATAACGTTCATTTTCTGCTCATCTCATAGTGATCAAACTAGTAATGCTCCTACTCCTGATTGAGCAGAAGCGTTATCCAGTGTAGATCAGTAATAAATCTCCATCCGGATGTGGGGCTGTGATTACGATGGATAAACGCGAACACTTTACGAGTTACAAAGGAGCGCGGAATCGACCTAAGCCGCCTCTGCCTGCCGGTCAGAGACACGCCAAGGGTCATTCGCCCTTGCAAGAGCTGCCATTGGAGGAGGGCTGACGCTGTTGCCGCACATGTGCACCTGCTGAGTCTTCGTGAACGGCTTGCCGTCGGCACCGTGGCTGATGATGTAGTCGGCGGGAAAGCCCTGGGCCTTGTACAGCTCGGCCGGTTGCAGCATTCGCAGGCAGATGTCGACGATCACGTACGGCGTGCCCTTGATGGTGACGGTGACCAGGCCGAGGCGGTCCTTGGTAGTGATCGTTGGTGCGGGCGCGTCGGCGGCGCTCATGTTCTCGGTGCCGTAGTAGCTGATCAGGAATGCCGCGACCCTCAACGCGCCGGCTTCAACTTCTGGCGAGAGCTGGAGCTCGACCAGCGAACTCTTTCCGCCACCGCCGGCAGTGATGGTTGGTGCCGGTTCGTTCACGGCCTTGCCGACGCTTGCGCCGAACTGGCGCTCCATGAATGCGGTAACTAGACCGTGGTGAGTGCCGCCGGCGCTGATCGTGTGCAGTGGGTCAGCTGCGTCACGCGCATCGCAGTTGCCGCGCAGGTGCACCAGGTTCGCGGTCACGAGCTGCTGCTGGCTACCTGTGTTCGTCACAGTGGTCATCGGGTCTTCGATGCTCTTGGCGGCCGTGGTGTTGAATCCGCCATTCATCTGAGCCATGAACACCGTGGAGATGCCCATGGCGTGGGCGGCGCCGGCCGGGCGCTGGTAGTTTCCACCGCTGGTGATGGTTGGCAGCGGCTCGTCGAGCGCTTTGCCTTCGTCCGTAAACCGGAATTTCACCAGGTGCGCAGCGGCAATTGAGTGCCCGCCACTTGCTGTCACCGTGCCAAGTGGGTCACCGGCAAACTTGCTGCCATCGCCCCAGCGCTGGACACCGCCGGGCTTTCCTTCGCCGTGTGCCGCGGTAACCATCACTGGGCTGATTAGCGTCAGCTCGCCGCGGTTGGCGCAGGTTACCGTCGGCAGCGGGGCGTGCGGATCGTTGATCCGGTCGCTGCCCTGGTGCGTAGCTGGCGCAATGATCGGGCTGGCCATGGCGAACGAACCGCCGCGAGGCCAGGAGGTCACTGTGCGCAGCGGATCGTGCGCTGACTGCACACTGTCGCCGGACCAGTTCGCGATCGGCACAATAAACGGGTCAGCGGCATCGATGACGAACTTCTTCATGCCCTTGGCGATCCGCCGCAGGGTGGCCGGTGCCAGCGGCTTTGGACGATCAAAGATGCTTTTACTCGGGATCGTCCAGTCGATGCACTCGGCGGCGGTGCGCCACTTCTGCTGGCCTTTCACCGGGTGCTTGGCGTGTGTTGGGGCTGGCCAGACAATCGGCTGACCATCGCATCGAGCGATCATGAACAGGCGTTCTCGGCTGGTTGGAGCACCAAAGTCACACGCCTTGATCACCCTCCACTCCACGACGTAGCCCAGGTGCTGCAGCTCGGCAACAAACACAGTCCAGGTCTGCCCGCGGCGCTTTGGGTCCGGTACCAGGAATTGCTGGTGCACTGGAACCACCTCGCCCTGTTCTGCCACGCCGCCGCCCAGCTTCACAACCCGGCCGGTCGACTTGTCACGCTTGGCGATCAGCGGCCCCCACTGAAGTATCTGCTTCACGTTTTCCAGGCTGATCACGCGGGGCTTCTTCTTGCCGGCCCACTTCAGGCCAATCCATGAAAGATTGCGTATCTCGCGCTTGCGCGGCTGGCCGCCGGCGGCCTGGCTGTGGTGCGTGCAGTCCGGCGACATGTGGAACCAGCCCACGGCCTTGCCGTCGCACTCGGTGTCTGGATTGCCCTCGAATACATCGGTGGTGTAGTGCACTGCGCCCGGGTGATTTACGGTGTGCATGCTGATTGCCTGGGGGCTGTGGTTCTTCGCGACATTCACCGCGCGGCCCAGGCCCATTTCCAACCCGGTACCAGCACCGCCGCCACCACAGAAGAAGTCGACAACGATCTCATCGTCCTGAGAGCTGAAGCCAAGTCCATACTGGGTTTTGAAATCGAAGGGGTGTTTCTTCTGTTGTGCGGACATAGAGGATCCTCGCCGGCTGGCGTGATTCGTTGAAGTGGGGTATTTGTGTCAGCCCGGCATGGAGCCGGAGGGAGAGACAGCAAGTGAGCGATGAGTTCTACAAAAGGCTATTGGGCATACCAAAGCAGAATCAACTTTTCTCGGGTAACTCGATTTTCGGTATTACGACAGGGGAAGACATTCTGAATTTCTCTGAATTGGATGCAGCAGGCAGCACTGTTGCTCACTACCGCGTGGTCGAGCAGCGAATTGGTTACTTAGGGGAAGGCGGCTCAATTACCTGGCACAGAACAGAAGTCAAATCCAAACAGGATTAAAACCAACAGGTGAAGGCGGGTCAGGCGAAGATGGCGAACTGTGCGGCCTTGCACTCGAGTTCGCCATGCGGCAAGCGTGTGATCTCTTGTCTGGCCGCGGCTACTTCGCCGGTGTGGCGACCATGCTCGGTATTGATGCTTACCGTTGAACCGTCTGGTCGGCGAATCATGCGTTCGCCGCGGGGGCCACGCTCAACTGCGTAGCCCAGTCGCCGCCATAGCCCGTTTGGACTTTCGAATTGTGGGGGCACGGTTGTCTCCAGTCAGGCGCCGCCCTCCGTCCAGAGCGTGGCATAGCGGTGAGTATCAGGCGGCTGCGCGCTTGAGTTGGTCAGTGAGCTGGGTCGGCAGACTGCGCAGCGTCAGGGTGCCGCCAGCTTCGTCGAACTCGATTTTCGAGCCGAGGAGGTGCTGTTCAAAGCTGATCGACAGGCCATCGATGCGACCGGTGAAACGCCTGAATTTGTTCAGGGTCTTCTTGTCGGCGGGAATGGTTGCCGACAGGCCGTAGTCCTTTTCGCGGATGAAGGCGGCGAACATCTTCGGCTGGTCCTCATCGATCAGCTCGGACAGTTCGTCGATGGTTATCGGCTCACCCAGCTTGGCGTGGGCCATGGAATAACTGACCAAGGCGTGAGTCTTCTCGCGGGCCGACTCTTCCCCCAGGTCTTCGCTTTCCACGAAGTCTCTGAACGCCTTGAGCAGGGTACGGGTTTCGCCCGGGCCGTCGACACCTTCCTGACAGCCAATGAAGTCGCGGAAGTAATCGTTTGCCTTTCGGCCGTTCTTGCCCTTGATGAACGATATGTACTGCCGTGATGCTGGATTGCTCTTCCACTCGCTGAGGTTGATTCGGGCCGCCAGGTGGATGTGATCCAGATCCAGGCGCCGAACGGGTAGCAGCGTGAGCGCGTCGGTCATGACCACCGCTTCGGTTTCTTGCACCAGGGCGATGATCAGGTAATCGGTCAGGCCTTGCTGGTAGTGGCAGAACAGGGCGTTGCCACCGACTGAGAGGTTCGACTCTTCCATCAGCTTCGTCAGGTGTTCGACGGCGTTGTCGCTGAAAGAAACGAAACCATCGTTGCCGGCCAGGTATTTGCCGAGCCAACCACTGAATGGGAAGGTGCCGGATTCTGCGTGGAAGAGCCCCCAGGCCTTGCCTGCCTTGGCGTTGTAGCTTTCGTTGAACTGGTTGATCAGCTCGTCGCGGGCTTGGCTCTCGACCAATTCGGCGCCGCTGTAGTGCAGAACTGCAGGGCTGCCGTCGGGCTTCTTATCGATCTTGTGGATGATGCTGTGGAGAACAGGCATTGCGATTACCTCGGGTAGGCGCCGCCCTCCGTGACCGGATGCGACAGTAGGTGATTTGGTTGGTTGTCACGCGTGGTTGTCACGAAATGCTAATGTGCGCACCGAGTTCTTCGTCGGTCATTCGGTCGGCAGCATGGATGAAGCGTGAAATCAGATCCTGCTCTTCGTCGATGCCGGTTCTTGCCATTGTTCGAATAAGAGCGGCGTCATCGTTGTGATAAAGCAACGTGACAATCTTTCGTGACAGGAGGCGAGCCAACCTTTCTTGCTCGGTCAACTTGTCGCGTTCTCGCTGATCGCGCTTCCTCTCCGTTGGCGACTTGGCCATGGCCTGCCTCTTCAATTTCGTGGGTGCTTGGTCCAGGCATGCTGCCAGCGACGTAAGCCTCTGTCAGATGCCGTTATAATGGCGGATGTGGTGTAGTGGCTATTTAGATGTTCTGTTAGAATCTTTAAAAAGCGTATGGATTTTTGTAAATGCGTCGTTCTCAATTGAAACTGGGTGTAAAGATTCTTAAGTTATTTCAGGGGAATGCAGAGCAGCTCGCGGGATTGTTTACGTCGATATATATTAGCGCTGCAATAATAATCGTTAGTTTGCGAGCGAATGAAATTTTCAATTTGCCTTTAAATGAGCTTGGCGATTTTCTCGCGGGCGTATTTGGGCCGCTCGCTGTTCTTTGGCTAGTACTTGGTTACTATCAGCAAGGTCGCGAACTGAAAATTAGCTCTCAAGCTCTTGTCGCGCAATGTGTTGAACTTTCGAACTCCGTGAGTCAACAGCGGCAAGCCCTGGAAGTATCTACTGGTCAGATGGAGTTGGCAAAAGCAAAGCATGAGCTGGAGATGTTGGAGATTGAAGAGTCTATTCGCCCTAGGGTTGATGTGGCCTATGTGAACTCCGGTATTTCTAATTCCGGTGAATGGCTCAATTTTAATTTTTTGATTATTAATGCAGCTGCCTATGGTCTGAGAGTTTGTTGGTCTGATGGAAGTGCAGAATATGAAGTGCTGACGGCAGGGTATGTCGGAGCGCAGGCTAGAGAAAAATTCCAAGTTAATTTTCCAAAAAATGATGTGGATGTAAGTTTCAATATAACTGTATCCTGCAAGAATGTTCGGGGAAGGCCGTATGCCTACCAGTTCACGTATGATTCATCTGTGGGGAAGGGTTTGGTTAAGGCGCACGAGCCATCGGCCCCCAAATTGGTTAGTTAGATGTCCTCATCCTGTTTCTTATGCTGATTCAACCAGAGCAGTAATGCCTGTCTGTGCGCAGTATTGTCTTTTCTCCGGCCCGTTTCGTTACAACGGTGTTCGCTGGTCGTTTCTATCGACTCTTGGCCATGGTCTATTTCTTCTATGCCGCTGGCCGGTAATGTCAGCCAGGCTTGTCGTTTGCGTTGTTGCACGCGTGCCATCCTGCGCATCAGGCTGATGCCGGGAAGTCGAGCGAGTAGTCGGCGATCAGCCTGCGGCATAGCGTTTCGCTGATGCCGAGGTGCTTGCTGGCCTTGTACCGTGTCATGCCGGCCGCTTTGCACTCCACCAACTGAGCGGCCAGGGCGGCTTTTTCGTCGTCGCTGATGAGTCGCCCGCGCTTGCTCTTTGGCGCCTCGATGTTCCGATAGCCGTACGCCGGCTTCGGGATTTGATCGACACCAGGGCTGTCCTTGCCAAGCCCTGTCGGGATCAGCTGCGCCTGACCCCCGGATGCAAAGAAGGCAGCTTTCGCCGCCTCCAGTCCACATTGCCGCTTTGCGGCTTCTTCAATTGCTTGGTCCATGTCAGGCACCGTTCAAATAGTGGAGGGGCGCGAAAGGGATGTCATCGTCGAAGCTGTCGGGCGGTGCAGCCTGCTGGTTCTGCGCTGGCCGGGATGCCGCCTGCTGCCGGGACTGTTGTGGCCTGGATTGCTGCTGCGGTTGATTGGCCGCCTGAGGCGGTGAGCCGACGAACTTGATCAAGATGATCTTGCCCGTCAGCTTGAAGCCTTCACCGCCGCCGGTCTTGGTGTAGGTTTCGATATGAGCGTCGTCCATGGTGAAGTACACCTGCTGACCTTTGAGCAGGTAGGGCGCCATGGCTTCGGCCTGCTTCCCCCAGAGGGTGGCATCGACCCACTGAGTCGGCCGCTTGCCATCTTGACCCTTTCGACCGTAGTCGCACGCCAGGGCCAGATTGACCACAGCGTCGCCGCCCGGGGTGTAGCGCAGTTCAGCGTCACGGCCAATGCGGCCGACGTCGGTAAGTGTTGGCATGGAATGTCCTTAAGCGGCGATGCCGAGCACGCGGTTCATGCGCTCGTCGAGGATTTCGTAGAAGGTTTTGACGCGCTCGTTCATCTTGCGAATCATCACTTCGTCGCGGTAGGCACGCTTCACAAACAGCTTCATACCCGGCCAGTAGCTGACGAAGTCGATCCACTCGCGATCCGACACCCACAAGCCGCCCTGGCACTGCGCGACATGCTCCTTGGGGATCTCGCCGGACAGGATCACTTCCACCTGAAACTTCGGCAGCTTGGTCTTGATCTCGCACAGGCCGTCTTCGCCGATTAGCGAGTCTGGCGAGTAGCCGATCCCGTGATTCAGGATGATGCCGACCTGCTCGGTGGTGACGTCCAGTTGCGACTGGTACAGGCCGCGGGCGATGCCCTCATATTCATGGCCGCGCTCGGTGTGGCGGTTACCCTGGAACGGATCGGCAGCTTCACCGGTGATGCGCTCGCCGATCAGCGTATTCATGTAAGTGAATGCGCCGGCGCCGAAGCCTGCTTCACCCTTGCCGTTGACCAGCAGGGTGTCCAGCTCCGAACAGGTCACGATGCCCAGGCGCAGATCCAGCCACTCTTGAGTCCCTTGCTCAACGTTACTGATGATTTTCATCGTCTTTCCCTTCGGTGGTTTTGCTGTTTTGGGTGGCTGACTTGGTGAGCATGGCCAGCACCTGGTCAAACATAGATTTCTCGACGGAGGTCGGTGTGCCGTGGATGCCGGCGAAAGCGGATTTCGCTTTGTCGCTGCACTTCTCCAGCAGCATCGCGAGCTGCGCGGCCTGGGCGGAGGTGACGCGCGGTGTGATTTTGGCAGCCGGGCCGTTGCCGTCGTCGTCTTCGCCAGTAGTGGTGATGTTCAGCAGCAGGCCCGCGGTGTAGCGCTTGCCGTAGCTGACGCTTGATGCCACGGCCTGCACGCCGTTTTTGCTGCCCGATGCGTCGACAGGCAGGACGATCGAGGTGATTTCTCGGTGCCCGGCGCGATGGCTCAGCACACCTTCAACCTCGATACCTCGCTCGTTACGCGGGGTGCGGAAGGTGAGGGCAAAGCCATGCTTGGCCATCACAGGCTTGATCATCTCGTTGATGTCTTCCCAGAGCGCGTAGGTGCTCTGGATCCGGCCGCTCTTGTCCTTGATGCCGCCGCGTTCGCCGATCACCGGCATTTCTTCCTGCATCTGGGCCAGCGCATCGTCGTACTGCTGCTTGGCCTGCTGGGCTTGGAAGCGCTCATGCATCGCCATCAAGCGTTCCATCTTGTCGATGTCTGCGTCGGGGCTCATGGCCACCTGCTGGATGATCGACATGATGGTCGCCGACTCGGTTTGAATGGCCGGCAAGCGCTCGACTTTTTCTGTCACTGCAAGATTGCTCATGGCGACCTCAGTACTTGATGGAGATGGCGGGGATGAAGCCGCTGGCGATCAGCATTACAGCCAGTCGAGCGCAGTCTTCGGTCATTCCGTGCTGCATGAATGCCTCTTTCGAAGCCTTGTAGATGGCGCCCTTGTGAACCCTGTCCGCCTCGCGCAGCTTTTCTTGGCGCAGGATCTCGTCTGCGGCTTTGTTCTGGCGGGCGATCTCATCAAGTCGAGCTTGCTCAACCGCTGCGGCCTGACGCTGCTCGGCTGCAATTCGGTCCTGCTCGGCGCGGCGAATGGATTCGACCCGATCCGCCTCGGCTTGCAGCTTCTGGCGCTCGGCCTGTTCGGCGGCCAGCTTCAGCTGCAGGGCCTGGTTAGCAGCGGCAGCCTCAGCCTCGCGGACTTTGCGTTCGGCGTCGCGCTGAGCCTGTGCGGCCTGATCAATCAGCGCCTGCTCACGCTTAGCGGCCGCATCGCGCTCGGCCTGGGCCTTTTCTTCGGCTTCGCGCTGAGCTTTCTCTGCCGCTTCCCGGGCGATTGCTGCTTCATGGTCGGCCTTGGCTCGCGCCTCTGCTTCAGCGCGCAGCCTGGCCAATTCCGCTTGCTCAGCTTCATACTTCTGGCGGGCGGTCAGGGCAGCGCGAAGCACCGTCAGAGCCTTGTCCTTGGCGCGGGCCGCTTCCGGCTCGAACTCTTCCCAGACATCGCCCAGGGCAACCGCTTCAAGCTGTGCGACTCGGTCGGCCAGGTCTTCGGCGGTGATGCCGTCCAGATCCACGGCCAGCAGTCGGATACGCTCGATCGCGTCGTTGTGCTTATCGACCCGGGCATCTTCGGCGGCCTGCCACTCATTCAGCGGGCGGCGAACCTCTTCCTGCCATGAGTCCAAAGTGTCGCGAACGCGTTTGCGCTCAGCATCGATCTTCTTCGGGACTTCCTTCAGGTCGGCGACCAGCTTCTTGCCGACGTCGTCCAAGGCCGTCTTGGAGCGGGCGACTGCATAAGCCATTGAGGCGATCGCATCGCGGCCCTTGCGGGTGCTGATGTCCGGCGTGAAGCCATCGATCTTGGAGCGGATCACCTGGAGCCAAGGTTCAAGGCCCTTTTCAGCGCTGTAGACGGCGAGGGCGGTTTCTTGCGGCGGCACTACGGCCAGTTCGGTTTTTGCGGACATGACGATTCCCTGCCGCGATGCTCGCAGCGTTTGAAGGTAGTGGTTATTGAGTGAGCTGGCCGGAGTAGGCGCTTGCCAGCATCCAGGCAGTGAAGAGCAGAAGGGCGACGGCTAAGCCACGCCAGGTGTGTATGCGCTTGGCGCGCTGATAGGAGGTCAAGGCCGAATCCTTACCGCGATCCGGCCGCCTTTCATGGTCGGAGCCAGGCGCTGCGGCAGGTTGGCGACCAACTCTTCGCGCTTGCGGCCGATCACCTCGTTGAAGGGTAAGCCGAAGCTCAGAATGGCGATGCGCTGCTCGATACCTTCGAGCTGCTCGTCGATCAGCGTTTTTACCGGCGCTGTGCTCATGACAACTCCTTGCGCTTCCGGCTGATCTTCAGCAGGCGAGCGCTGTAGTGGTGAAATTCTTCAACGGTGATGTCGCCGGCGGTGAAGAGTCTTACGAGCAGCCCGTTGGCGAGGCTGTCGTCGATGTCGCGGCTGCCGGGGTGCTCCAGGGCTTCAAGCGCCTGATCGATGGTGATATGCGGGCTCAAAACCCGCACTCCGTTTCTGCTCGATCCTGCTCGCACTTGGCGTCGAAGTAGGCGTCGGCGTTACGCTCGGCCATTTCCCGGGCCAGTCGAGTCACCACACAATCGTCGCTGTAACCCAGGGCCCCGTGCGCCAGTTTGTAGAGCCGGCTTTCGGTGTCGCCGCAGCTCACTATCTCGATGAGGATCTGCGCGACGTTCCGCTCGAAGTCGGGAGTCGCTTGCAGATGCTCGTCAACGTCTCGCGCCAGATGCTCTCGGCTCGCGAGGGTGGCGCCGCGCCCATAAGGGCTGGGTGCAACAATCGGGTGCCCATCGATGAGGCCCTGAGTAGCCTCAATCACCCATTCCTGAGCTTCGGATGTCTCAAGGACGCTGTCGCCATCATCCGGAGGCAACCTTGAGTCGTATGCAGCTTGTGCTCTTGCGAGTGCGTTCATGGTCGCCTCCAGGGTGGCGCGGTGTTGATCCAACATAACTCGGCTGCACTCATCCATTCCGCTGGTTGCCGTTGGGCGCGGAGGGGAGTGCATGCGGGTGGTGTCGGGGAAGAGATTTAGCTGCTTGCTATGAACCCAAAAGAGCAGAATGCGCTACCGCCCTAACTATGGAGACGATGGCAATTGCACTGGTCGATGGGCTTTGTGAGGATGAACTTACAGAGTAGGGGCACTGAATTGCATTTGGAGGAGTATTCGCCTTCTGGCGCAGCCGGTGTCTTAACCGGATTGGTGCATGGTCCGACCGCCGTGGCGGTGATGTCACGGCAGTTGACTAGATCGCAGGACTTCAGAGTCGATTCAAATTTTTCAGCTGCGGTCGACTAAGGTCATTCTGGTTGCAGGAGGGATCGGGGTGATATGGTGGCGGTATGCATCTGTAACTTCGTTAATCACGAACCCAAACCGTACTCCGATTGCCTTAAGTGCTGGGATTGATAAGGCAATTACCTGGTTGTTAAAGGATGCCGAGACACTATCAATGCCGGTTGCCTTGAAGACGGAGTCAGAATTGCTGCTCCATGCACCAACTACATTTTCGATGGAGCCATCGCGCATCGTGAAGCTGCCGCCACATGCCCCGTCGCTTCCTGCGGAGCAAAAATTAATTAGTCCTTCATTTTGAGCAATGTAGAAGCTCCCAGTCCGATCGTAGATCAGCCCCCGTGCAATCCTTGCAAACCCTTCCGCGCTACCGCTCAGCGAAAGGTTCCAGCGGTCGTTGGACCAATAAAGCTCGACGTGTTCAATGATTTCAACAATTTTCATCTAAAGCCCTCAGTTGACGTGGTGTTTGGCCCTGTCTCCAAGGCCAGCTAGTGACAAATATTTGCCGTAGCACGCTACTGGCGTCGCACAGGCTATATCAAATTATTCCACCGGTCGCGGCTCAGCCCACCAGAAAACTGTTTGCGGTGCTTTACGCTGCACACCCGGGTCAGTTGCCAACCCTCTGAACCGTTGAGGCCGGTTCATCGCTGCCTTTCAATCTGGGCCGGTGTTGATCCGGCAAGGTGAAGCGTTAGATCTAAAGAGCGGTCAGGCCCTTTGAGGCCCTTCGCGCTGGCGGTCCCTTTCGGGGGACTTGGTTGCGATGGCTGCACAATACCGCCGGTATTGTATGCAGGTCAATACCTCCGGTCATGTTTTTATCGCGCCCACAAAAAAGCCCGCTCAGTGGCGGGCTGGATCTGTCATTAGGACTATTCGCGGCGTAGCGTCGGAGACCGTCCGTATTTCGTTTCGTACTTTTCGACCATCATCTGGCAAGTGCCGCGAACGAATCTGCGAGTGCTCAGGGATTGGAGCTCATCGTCGACGCCTTTCCAGCAAAGATCAATCGCTGAGCGGGCCTTTGTCTTTTCATCAGGCGGCCCTGACATGGCGCCGACGACCATCAGCGTCCCAAGGATTAACAGTGGAGTCAGGATGATCCATGGCCAGATCGGCTTTTTGGATTTTGGTGGCGGGGCGCCGTCAGCTGTACCAGTGAGCAGGCTCACCTGGCAGTGTTTGCACCGGATCGCTTCCGCCTTGATGGGTTCGGCGCAGAAAGGGCAGTTCTTGTCAGGGGCGTCCAAGGATTGATCTCCATATCAGGGATTGTAATCCTACCATTCTGGCCCCGTGCTATCACCACTACAAAGCCCGGCATTTGGCCGGGCTTTCCAATCACGTAACCAACTCCTTTTGGCTGACCGTATTGTGCAGGGTGGAGATGACGAAGGTGGACAGGGCGGAACAGAGAACTTGCACTAGGTTCCGCTACTCTTGTTCGCTTGATAATGTCCAGCCGGCTACGTATAAAATATGAGATGAGGGTGATTTCTCGGGCAATTGTGTGTGACTATCGATCTTGAGCTCTTCGCGCCGGGTCCGTTGAGGTGGAGCGAGAATACTTTTCACCCCTAAGCCTATTTTTGGAGTTGAGTTTCTTTTTCGTGCAGCCTCCTGAGAAGAGTCAGAGAATGATGCATTTCCAATAAATAGACCGCAACGATTTGCTTTACGCCGCTTTTTCCTGGATATGGCAATCGATACGAACGCCTCACCCTCGGCCTCAATGGTTTTCTGATAGTAGCTGATGTGCGCAATAAGCCTTTTTGCCAAGGCTTCAAAGCCATCGCCCTGTTTCGCTTCCCACATCACCTTGTACAGCTGGCAGAGCTGGTGCCATTCCTTGCTGTCAACATGCGCAGGCCTGTGAAGGCCCAGGACACTAAGAAGTGCTGTAAATTTCTTAGGTAGCGCCATTCGCTGTAAATCTGTTGGGGTTGGCAATGCCATGATCTTCTCCTTGATATCCAATTTCCTGTGGAATCGGACTTTTCGTGAGAGCGCTATCTTCGATCCTTCCTAGCCCCAACCAATCTGATAACGATCAGCTCATCAAGAAACGAAAGGCCCGGCATTGTGCCGGGCTATTCCTCATCAACGCTATTTGTCCAGCTTTTTGAATTCTTTGCTCGAAGCCTTGAGGTCGCTCTTAACTTGTTTGAGGTCTCGCGCGAGAGGAAGACTTTCAGGTGCATCTCCACTGATCTCAATCATGGTTTCTCGTACCTTCCTACCGACCGCTTCTGCAGCTCGCTCAGCAGCTTTTTGGCCGCGTATTCCTTCGTTCTCCATTTTTGCTTCAGTCTGGGTAACCCGGAAAAGGTTGGCAGCAAGCTCCTGCTTGCCCATGAAGTCCAGTAGGGATCGGCTAGACTCTTTGCCAATCAAGCCTTTTCTATTTTTTAGGTCAGACATATTCATGTTATACAGTCCGCGGTATCCCGCGTTCTGGAAAAAATGGTACTCGGTGACACCGGCCTGCTTTGCCACTCCACTCAAAGACTTCTCGTGTAGCGATATCTCATCGCGTATCAGTACGCGTTCAACATCCTCTGCCTGATCGATGTAGCGCTTGAACGTCTCTGCTACGGCAGCAAAATACGCTTGAGCTCGCGCAACTTCTGGCTTTTTCCCATCACCATTCATTGCTGTCAAATAGCACGCGAAACGCGAAAGCTTGTAATCTCGCTCAATTTTTCCGTCAATTTCTCGATCGACCTGCTGGAAGTTTTCCATGATGTCGATGCCGAGGGTAGTGCAAGATGCAATTGCTTTTTGGACGGCCTTTTGAAAGCTTGAAAAGGTTTGATAACCAACCATTTTCATGAAATCACGGGCATACCAATACGTGATGCCGTTTTTCCGACACAGGCCATCGAAATGTGGCCGAGAGTCGTCGAAGTGGAAAACGTCTTGTTCATTCATCGGTATGGCCAGGTCGAGTTGATAACCCTCAATTTTACCCATAGATCGCGTTCCTTGCCTTCGGTTTGTCAAAAAAAGTAGTACATGGTTTTGTTGGTGCAGACGCTCAGACTCGACCGAGTGGGTCTTCCCCGCACAATCCTTCCCGCCTTCACCTTATCTGCATAACACGCCAGCCGACCCTGTGGGGCTCAGCCCGCCCCAACGATTCTCAATGCAATCGCAGCCTCAAGAATTTTGTGTGCCTGAGACAAGACAGATTCAGACAATTCGTCACTTCCAGCTTCTTTTAGAGCGTCCACCACATCAAGCAATCTAGCTACCTCGGCCTCAATGATGCGGATGGAATCGCCAATCTGGTATTGAAGTGAGTGCGCCATCTCAATCCACCCTCAAACCACAACGCCTATAAATCCCCACCGCGCCAGATGACCTGGCCGATGATGCGATGCTCGTTGATTTCCTTCCGAGAGAGGATCAGGTCCGGGTGCTCATCTTTGTTCTCATTGTCGCTTCTGATGATCCAGCCGCCCAAGGTCGTCTTTATTAGTCGCTTCACAATCGCGCCTTTGTCTGCACTGGCCAGTACAAAGACTTGTCGGTCGATCGGATCGATCTTCGACCTGTCGATCAGGAGAACGTCGCGATCGTTGATCGTGGGCCACATGCTCTCGCCATCGGCATAGATGACGACCAACTGATTAGGATTAACCCCCTTAACCTTCAACCACTCGCGCTTGAATGCCAGGGTAGAGCGAACCTCTACATGCGGGTTCTCATGACCGATGCCTGCTGCAGCTTTAGCATCGTATTGAGGAATGAAGGCGTATCGGTCGTCAAGACTGTGATTGACGTCATCGCCAGCGGGAAATGGCGTATTGGCGGCGACACCACCTACAAGCTCTCTCGCCATTCCCTGCTCATGTGAAGGGGTTAACGATGAACTGAGTTTTCCTAGTTGCTCAGCAAGTGTAGGACTGAAGTCGGATACCGGGACCTCAAGCATGCGCGCAAAAACCGCAGCAGCCTTCAGACTCAACGCGGTGCGACGATTCATGAAGTGGCTGACAGCGCCTTGCGTAACACCGTCACCAAGCTCTGCAGCGAGCTTCTCCTGGGTGAGTTTCAGCGCGCCGCGTTTCCTCTGAAAAATTTCTTTCAGGCGGTCGCTGTCTTCCAATTGCCATTCGGCAAGCGGCAGTCTTCGAGAGTCTTTAGTCATCGGCAAATCATATTACCTGCGGTATTCACTCAACCAATATCGCCGGTATTGACTGATGATAATACCGGCGGTCATAATTGGCGCGAAAACTATGTAGAGGACGTCGCTATGCGCCGTATCCCGCTTTCCGAATTTGCAAAACAGCATGGCCATACGAAGGCCGCTCAAATGCTTGGCTGCACGCAAGGCGCCTTAAGCAAGGCGATCCGTGTTGGTCGTGATGTGTTCGTGACCCTCGGGGATGACGGCAGCTTGTCGGCCCTAGAGCATCGTCCGTTCCCGTCTCAAAAATCTGCCGCCTAATCAATTTCAATCGCAAGGAGCAAGACCTGCATGTACGCCAATCCCAAGCACCTACATGACCGGGAGATCAAGGTCCGGGTTGATGAGGACACGTTCGAGTTAATCCAGGCCCTGGCCAAGTTTCACCGCACTCAGCGAGCGGTTTTGTGCCGTGAGCTGCTGGAAGCGCAGCTTGCTGCATTGGCTTCGGAGAATACCGACGAACACCAAGTGGCTTGAAGGCCCAAAGGAGGCCCCATGCCTATCGAACAGGTCCAGTTGGGCCAGCGAGAGATGGAGCAGCTTGAGCGAGAGGCAGAGAAGAGGGGGATAACCCCCGAAGAACTTGCAGCCGAGTTGATGCGTCGAGAGCTGGCTCAACGGACAAAACCCCGAAATCCGCGGGGAGCAGTAAAGCCTTTCCGAAGAAGGGACTGAGCAGGCCCTGAAGCGTAACCGCAAAGCTCATCCAGACCACACGATCACAGAAGCAAGCAGGGGAACACCTGATGGCCTATGACGACAAAGCCCACCGCCACGACCACCAGGTCAAGGTTCGTCTGGATGACGAAGACTTCCATGAGCTCAAGGGATACGCCCATGAGCTCAAGGCGCAACACAGCGTGCTGGCGCGCGAGATCATCCTCGCCGCCCTGGCATTCAAGAAAGAGCACGGCTACCTGCCGTTAATTAGCGAGAAAAAGCTCAGGGCCTGAATAGGTCATGGGAGGACTGATGCCAGCAGCAAACGATGCAACGCCAATCCGTGAGGTTGAGGTCGCGCAGTTTAGGAAGAACGACTTCGAGGACCTGGAACTTTGGGCCTCGGAGATGGGGTTAAGCACTGATGAGCTGGCATCGCAGATCTTGCGCAAGGCCGGTCGGTTTCTCTCGCGGAGAGGGAAGCCGGCAGCGGGCGACAACGTAGTCCAGTTCGGACCGCGAAGGTGAGCTCTCAGTCTCTTATTAGGGACTGAGGAAAAAGGTCCCTTTAGAGGGACTGAGGTTTTCAGTAGGCAAAAAAAAGCCGGGGTAGTGACCCGGCTCTCTTCAACGCTTGTGGAGCGAATCATGCACCATTCAATAGAAACCAGCAATCCCCAGAACCATGTCGCGACACGTTTTATGCAATCGCAAAACGTGTCGCGGACTATTTCGAGCATCGAACTTCGCGACATGGTCAACGAGGCGCGCAGCCAGGCTGGCGAGCCGAAAGTCAGGAACGACCAGTTCATTATTCGAGTGCAAGACGAGCTCGGTGATGAGTTGGGGGAGTGCAAAACAATTGCACACCCGCAAAGCCGCGTGGACATGGCCAGCTACGACCTGACCCTTGATCAATGCATGCTCGTCGGCATGCGCGAATCGAAAGCTGTTCGCCGATCCGTGCTGCAAAAGTTGAAGGAGCTCGAGGGGCCGCGAGTCATTGCCACGCTCCCCGACTTCTCCAATCCCGCCGCCGCTCGTGCCTGGGCTGAACAGTTCGAACTGCAGCAGGCTGCCAATCAGGCCTTGATTGAGGCAGCTCCGAAAATAGCCTTCGTTGAGAGGTACGTCGATTCGACGGGGCTCAAGGGCTTTCGCCAGACAGCCAAACTTCTAAAGGCCAACGAGTCGCGGTTCCGCGAGTTCCTGATCGACAAAAAAATCATGTACCGCATGGGCGGCGAATGGCAGGCCTACCAGTCTCACATCGACGCAGGGCGCTTTGAGGTCCGGGCCGGCACCACTGACGGCGGTCATGCCTTCAACCAGTCCAAATTCACTCCCAAGGGCGTCACTTGGGTAGCTGGCTTGTGGGCTCAGTACAAACTCCAGGAGGTCGCATGATGGCCGCGCTCCCTTACATGCAGTTCTACGTCGCCGATTATCTGGCCGATACCACGCACCTCACTGCGGAGGAGCATGGTGCCTACATGCTCCTACTGTTCAGCTATTGGCAGACAGGCAAGCCTTTGCGCATTGATCGGCTCGCCACGGTTGCACGGATTCCCAACGAGCGTTGGCCTTCCGTTGCCGAAACGTTGAATGAGTTCTTCCATGTCACCGAAACTCACTGGGTTCAGTTCCGTGTAGAGGCTGACTTGGAGGCGGTCAACAGCAAGGTGGTTACCGCATCGAATGCCGGAAAGGCCTCAGCGAAGGCGAGAGCACTCAAAAAACAACAGGAACTCAACGACCGTTCAACGATCGTTGAAGATCCGTTGCAACGGAATGCCAACCATATAGATACAGATACAGATACAGATAAGAATAGAAAAGAGCACCCCCTACCCCCTGAAGGGGAGGACTTGTTCGCCACGTTCTGGAGGCTCTATCCGAACAAAGTCGGGAAGGCAGCCGCGCAGAAGGCCTGGAAGAAACTCAAGATCACTGGCGACCTGTTCACCCTGATCGCCGACGGCCTTGCCAAGCAAGTCGTGTCGACTGCCTGGACCAAGGACAACGGCCAGTTCATCCCGCACCCGTCCACTTGGCTCAACGGTCAGCGCTGGGAAGACGAAGTGCCCTCGCCGGCGCTGGCGAGCAATGTCCATCAGTTCGCCCCGCGTCGTCAGGCCAATGGCCCAGATTTTGACGACAAGACCTGGGCTGATGACTTGGGGGTACTGTGATGAAGACCCCGAATCAGCTGATGCAGACCCTGGGTAACCTGCCTTCCGTGGAGGCTGCCCCGCTCAAGGTCGACACCGGTACCGCGGATGTCGTGAACTCGCTGTTCAAGGAATTGCAGGCGATCTTCCCTGCGTGGCGGCAGGCATGGCCAACCGATGAAGCCCTGATGACCGCCAAGCGTACCTGGGTGAAGGCGTTCATGGCCGAGGGCATCAAACAGATCGAGCAGATCCGTTTCGGCCTGCAGAACTGCCGCAAGCTCGGAAGCGACTTCGCGCCGTCGGTAGGCAAATTCATCCAGATGTGCCAACCGACCCCAGAAGCGCTGGGCATTCCGTCCCACGAAGCGGCCTACGCCGAATCCGTCGCCAATGCTCACCCGAGCATGGCAGGCGGCCGGGAGTGGTCGCACCAGGCCGTGTACCACGCTGCCAGCCAGTGTGGCTTCCACGCGCTGAACACGATGAAGGCAGAGGTCAGCCGCAAGATTTTTGACCGCAACTACGACATCACAATCCACATGATGCTGGCCGGTGAGAGCCTGCGGAACATTCCGTTGGCCCTGCCGGAACGGGTCGACGGTCGCGTTACGGCGGCGATCGGCAACAAGGCCCTGGCTGACTTGCGCAAGAACCGGGGAGGGCATGCCCATGGGTAAGCCGAGGAGCAACAAAACCATGACCACGCTGGCCTGCACCATGGCTGGCTTCTCCATCGGCGTGTTCTGCGTCCTGATCACAATGGCGGTGACGTCATGACCGACAAGATCAGCGTCAACAGCCAGGCCAAGCTTTCCGAGGCCATCACCAGCCTGACCACCATGTACCGTGACAAGAAGTTCGTCGTTGTGTCGCTGCGTCCAGGCAAGGATCGCACCCTCGACCAGAACGCCTTGTGGTTCTCGCTCTACCAGCGCATCGCTGCGATGACGCAGATCGGCGACGTCGACGATGCACGCCGGTACTGCAAGCTGCATTTCGGGGTCCAGATCCTGCTGAACGAGGAGGACGACTTCCGCGCGGCCTGGTACCAGACCATGCGTCACCTGTCCTACGCGCAGAAGCTCGACATGATGGGGGGCTGCTCGCTGTTTGGTCCGGACGGATTCCCGGTAACCCGGTTGTTCAGTCGCGCCCAGGGCATCGCCTACACCGATCGCATCGTTGCCGACTTCACGGAGCGCGGCGTGGTGTTCACGGATCTGCTGGGCGAGGTAGCAGCATGAGGGCAGCCATCAAGGAGAAGAAGGCACCGAATCTGAAGAAATGCCGAGTCGAATCCTGCAGGGCCTCATTCGTCCCGGCGCGCCTGGGGCAGGCGGTTTGTAGTCCCACCTGCGCAATTCTGGATGCGCCGAAGAACTTGGAGAAGGCGCGGAAGGCTCTGGATCAGTTCGAGCGCAAAGAGATCAAGGTCCGTAAGGAGAGGCTGAAGAGTCGGGCCGATTACCTCAAAGACACGCAGATCGCCTTCAACGCTTGGGTACGCGCCCGTGACGCCCAGTTGCCGTGCGTTAGCTGCGGCCGGCACCACCAGGGTAAGTACGACGCAGGCCACTACCGGACCGTCGGGAGCAACCCCGCATTGCGTTTCGAGCCGCTCAACTGCCACCGCCAGTGCTCGCCGTGCAATACCCGACTTTCCGGGAACATCGTCAATTACCGGATTGAGCTGGTGAAGCGGATCGGCGCCGAGTCGGTCGAGTGGCTGGAAGGCCCGCATGAGGCCAAGAAGTACACCATCGAAGAGCTGAAGGCGATGACTGCCGAATACCGGGCAAAGACCAGAGAGCTGAAAGGGAGAGCAGCATGAAGATCAATTCTGCACGCCAGGCATGGCATGACTGCACGTACAACCCGGCCCCGGGCCAGACCTCCGACGCCGCCGAGTTGGGTGTAGTGGTCCAGGGCGCTGAGCGCGGGCCAACAGCGAATCACGCAGTGCACGGCGCATTGGCTGGCCAGATTCAATCGGCGATCGCGCGCCTTCACCGCCAACTCCGCGCATTCGGCAACGCCATGTATGCGGCCGAGCCGACCGATGATGACCGGGAAGAGGCGGAAGAGGCGGTGTTCAATCTGGCATGCAGCCGGGCACCGCGCATGACCGCCGACAAGAGAGAGCGAGCCGAGTACGTGGCCAAGGGGGTGTTCCGTCGCTACCGCTACATGCACCAGGGCGGCCAGTCGGCAAATGATGACCCGTTGATCAAGCCCGAGCTGTTCAGGACCTGGATGAATGCCGAGTACGGGATCAAGCTTCCATCCGCTGCCTGGGGCCGAGACTGGGAGCCATTCGTGCAGCTCTGCTTCGACGCGTGCTACGACATCGACGCGAAGGCGCTGAGCCCGATCGGAGGGGTGATTTACAAAATGAAAGAGGCCGCTTGACTTCCCGCACGGCTGACGGCATTATTTCGCCACTGTTAGAGTTTTGCCTTCGGCAACTTACTCGAAACTGACCCAGAACCCCGCCACCGAGCGGGGTTTTTTGCGTCTCCAGTTTCTCCCCGCGCCATGGAGCGGCAATTCGTCTCGCCCCAATAGGCCCTCATTCGGACCTCTGCATTCGCAGTGGTCTTCCCGTATCTGGCACCCATGCCCCCGTCTTTGCTCTGAGCGGATGAGGATGGTGTGGAGCGCCAGACCAATCTCGCTCCCCGCAAGGGAGGAAGCTGGATGTCACATATGCCAGAGAAGAACCCAGAAACCTGGCTCATCATCATGGCCTGGCTTAGCCAGAACTCACCGATGCTCTATGCCGCGGCGCTGTCGTGCTGGATCGCCTTCTTACGAGTCATCTACGGCGGCGGGGGGAGGCGACAGGCCGTGCTTGAGTCCTGCCTGTGTGGAGCGATCACAGCCGGGGCATTCCCGCTGCTCGAATACTTCAACCTCCCATCAAGCCTCGCAGCTGCCGTCGGCGCCGGCATCGGCACCCTCGGCGTGAAGAAGGTTGCCGCCCTGGCCGACCGATTCACCGATTTCAAATTGCCCAAGCGGCAGGAGTGACTCATGCAACTGATCGACAACTGGAAACAAGCGCTGAGCATGACCAGCGTGCAGGCGGGTGGCGCAATCGCTGCCCTGGGTATCGCCGAGCAGCTGATGCCGCAACTTCAGGCAGTGCTGCCACCGGTGGCCTACGGCGTGTTGGGTCTGCTGGTGATGATCGCTCGAGTGGTCCTCCAGCCGAAGCTGAGCAAGTAACCAATCCCGCGACACAAAACAAGCATCGCGAAAACGTGTCGCGGAATAGGACCTAATTATGACCGAGGCAAAACCACGAATTAAGATCAAGGCCGTGATGGTGCCCACCACCGACAGCCTCTCGAACCTGGTAGCCAATCTCGGGACCGGTCGAGACAAGCGCACGCACAACTCTTTCGGCTTCGAGTTCGTCAATCAGTTCGAGCTGGAAGCGGCGTATCAGTCCAACTGGATCGCCCGCCGGATCGTGGACAAGCCGAACGAGGATGCATTGCGTGAGTGGCGTAAGTTCAGCGGCAAGCAGTCCAAGCAGATCGAATCCGAAGAGCGTCGCCTCGGTGTGCAGCAAGCCTATCTGGATACCTGCTGCTGGGCTGACCTGTACGGCGGTGCGGCGCTGCTGATGGTTACCGGCCAGGACCTGAGCAAGCCACTGGACCTGAACAAGATCAAGAAGGGCGGCCTGAAGAATCTGGTCGTCCTCGATCGCTGGGACATCCAGCCGATTAAATTCAACCTGGAAGACCCGCTTAAGCCGAACTGGATGCAGCCTGAAAGCTACATGATGGTCAATGGCACCCAGGATATTCACTACAGCCACATCGTCCGCCGCACTGGGGCTCGCCTGCCGCGCCGCATGCGCATGTTCGAGCAGGGATGGGGCGATAGTCGCCTACGCCGCTGCATGTCGGACCTGCGCGATGTGGTGGCCACCAAGGGCGGAATTGCCTCCCTGGTACTGGAAGCCAATGTCGACACCATCGGCGTGAAGAACCTGCAAGGGGCCCTGGCCAGCGCGCAGAGCAGTCAGGTCACTGAGCGATATCGCCTGTTCGGCATGCTCAAGTCGATCGTGAACCTCGGCCTGCTGGACATGGACAACGAGAAGTACGAGCGAAACAGCATCAGCTTCTCCGGCCTCAGCCAGATCATGGAGCAGTTCATGGTGTGGACGGCAGGCGCCGCTGAAATGCCGGTGACCGAGTTGTGGGGCCAGTCAGCAGCAGGCCTCAGCTCAACCGGTGAGGGCGACCTGAAGACCTACCACGGCACTATCAAAGGCAAGCAGGACGGCCAAATGCGTCTCGACCTTGAGGCGCTGGACCAGGTGCTGATCCGCTCAGCGCTGGGCAGGTACCCGGACGGCATCGAGTTCGAGTGGAATCCGCTGTCGCTGCCTTCGGGCAATGAGCAGGCTCAAGAAGACCTTGCCGACGCTCAGGCGGATGCGGTGAACATCGAGAGCGGTGTGATCCGCCCAAGCCATGCCATGCGCCGCGCACAGGGTAAAGGCACCTACGCCATCACCGATGAGCAGATCAAGGCTCAAGAGCAGATCGAAAAGGACCAGGACAATGGGCTTGGCGACGACGGCAAAGACCTCCCCGGTTTCTCCCTTGGCGAAACTGACGGCGACAAACCAGGTGCTGATGGAAAAACGCCGGAAAAAGCCGAAGGGGCCTAAACCGGTCATGCCCAGCAAGGACGCTGAGCGCTACTACCTCGGTCAGATGCGCGCATTGGTCAGGGCGATGGCGACCGATCTGATCGCTTCGCTTGAGCCCGCGCTGAAGCGCCTGAAGCCCGACTACATCGCAGACAGTCGCGTGACACTGGATGGCAGTTGGACCGACGAAATCCTCAAGTCGATTCGCAGCGTGTCCCAGCGCTTCACCTCCCCACTGTTCGAGGCGCAAATCCAGCGGGTTGCCGCAACAACCATCAGTCGTGCTGACGCCGACAACGCCGAAGACTTCCGCGACTCGATCAACAAGGCAGTGGGCATCGACTTCCAGCTGGTCACCAAGCCCAAGGGCATGACGGATTTTCTGGAGGCCTCCACCGCCGAGAACGTCAACCTGATCAAGTCCATCCCGGCCGACTACTTCAAGAAGGTCGAGACGATTGTGCTGGGGGGCATGAAGGACGGCCTCGCACCGACCACCATCGCCAAGCAGATTCAGGAAGAGACCGGTGTCAGTGCGCGCCGGGCAAAGCTGATTGCGCGTGACCAGGTGTCACAGCTCAATTCAGACCTGACCCGGCAGCGCCAGACCGCAGCCGGAATCGTGCACTACAAGGTCCAGGATGCTGACGACGTGCGGGTATCCGGTAACCCGTCCGGCAAGTACCCCAACGCGAAGATCAGCTGCTGGGGTATTGCTCGGCAGGACATCGGCTACGGGCCTGGGGTTTACAAGGTGGCGGAAGGGGCGACCTGGAAGGGTGTCACTAACCTGCACCCGGGCAAGCACCACCCGCTTTGTCGCTGCATCGGCATCGCCATGATTCCCGGCGTGAACTATTTCCCCGACAAAAACGGGTAACCCATGAAGAAAATGTCTCTCGACGAGGCCTTCAAGCCTACGTCGCGCACCGTCACGCCTGAAGGCTTCCTTTGCGTGAAGGGAGTGGCGGCTCGTACCGGTGTTTATCAGTACGTGTCGACTGAGCTGGACCTCGACGGGCCAGAGCGCATCGTCAACGTCTACCGCCCGCCGGCTCAAGTGTTCGCCCCTGAGTCGATGGCGACGTTCCCCGACAAGGATGTGACCAACGATCACCCGGACGACCTGGTCGACTCGACCACGTTCAAGGAAGTGTCCGTGGGCCACGTCCGCGGAGTCGAGCAGGACGGCGACAACCTGGTGGTCGACCTGATCATCAAGGATCAATCAGCCATTGACGACATCCAGTCCGGCAAGGCTGAGCTCTCCCCCGGCTACCTCGCCGAGTACGTCGAAGCACCGGGCATCGACCCGGTATCCGGCACCGCCTACGAGTTCGAGCAACGCGACATCCAGATCAACCACGTCGCCGTTGTAGAAGCAGCGCGAGGCGGCAAGGTCGCCCGCATTTTTGACCACAAACCGAAAGGTGTACCAATGGCACAACGGAAAGTCTTTTTAGACTCCAAGAAAAGCCGCTCCATCACAGTAGACGAAGAGGTTGCTCTGGTAGTCGAAGACGCCGTTGCAGCCCTTCAGAAGTTCGCTGATGAAGAGTCGGAACGCGCAGACAAGGCCGAAGCCACCAAGGACGAAGCCGAAGAGAAGCTGGAAGAGGCCAAGAAGGAAACTTCTGACGCTGCTATCGGCGCTCGCGTGAAGTCCACCCTCGACACCATCGCCCTGGCGGCCCGTGTCGTGAAGTCGTTCGACGCGAAGGGCCTGGTGTCCCCGCTCGAAATCAAGCGCGTCGCTATGGCGCAGCTCAAGCCAACCCGCGACTGGGCAACCAAGTCCGAGGCCTACGTGCTGGCCGCCTTCGACGCCGCTGCTGACGAAGCAGAGGAAACCAAGGACGAAGACGAGGACGACGACAAGTCGAAAGTCAACGACAGCCTGAAGCGCTTCGCCGAGGACGCAGCCAAGCGCGGCCTGAAGCCAACGCAGGACGGTACCGACGCTTACAACAAATACCTGCGGGGTGAAAAGTAATGGGCGTAGCAATTGATACCTTCGGCCAGTACGCCGGCAAGGCCTACGAGGGCCAGATCAATGACCTGTCTATGGCGGACGTCACTTCCGCCGTCGCCTCGGTCGCCATTCCGTTCGGTCGTGCCGTTGTCTCTGACACCGCAGACCGCTCGGGCAAGCTGCCTGCCGCCGGTGCCGGTTTCTTTCTCGGTATCTCGGTGCGCAAGCCAGTCGGCGTGAGCGGCAGCTACCTGACCGGTCAAGTGTCGGATAGCGGCAACGCCGTCGGCGGCTACCGCGCAGGCGAAGAAGTCAGCCTGCTCTCGCATGGCCGCATCTGGGTCAAGACCCTGGCCGGTGCCGTCAAAGGCGCCAAGGTTTATGCCCTGCCAACCACCGGCGAGATCACCAACGCCGCCACCGCTGGCAACCATGAATTGGTCGGCTGCACCTTCCTGACTGCCGCCGCCGCGGGCGAGCTGGTACTGGTTCAGGTCAAGGCTGTCGCAACCACCACTCTCGCTGCTTAAGGACTGACTAATGCGAACTTTCGACTCTTCCCCCCAGGCGCAACTGGGCTTCCTGATTGGTCAACTGACCTACGTTGAACAGGAAGTCCTGCGCCAGCCGTACCCCGAAATCAAATACCCGTCGATCCTGAACGTGGATACCTCGGCCCCGGATTACACCGAGTCCATCGCGTTCAAGGTGCTCGACTACAAGGGTGAGCCGGCGCCAATCGGTGATAACTCCCATGACTTCCCGCTGGCTGAGATCGCAGCCAAGGTCGGTGGCGTGGACGTGATCCAGGGCGGCCTGGGTTACAAGTACACCCAGATCGAAGTGGGCAAGGCTCAGGAAATGGCGAACGCCACCGGTTTCGGCGGCGCCATCAATTACTTGGCCGAGAAGCCAATCGCTGTCCGCACCCTGACCGAGCAATGGTTGGATCGTGTGGCAATGGTCGGTGATGCTCGCTGGCCTTCGCTGGCCAATGGCGGCCTGCTGAAGTACCCGGGCGTTCCTGTTGTGGCGACCGGCACCCTGCTCGGCGGCGCGAACAAGACCATTGCGGCCATCCTGGCCGGTGGCGGTGAGACTGCAGCAAACGAGATCCTGACCCTGCTGAACAACGCGATCCTGCGTGTTTACAGCACTCAGACCAACTCGATTTTCCGCCCGACTCACATCCTGCTGCCGCTGACCGAGTACGGCCTGCTGACCACCTTCCGAATTCCGAACACTTCGGAAACCTTGGTGAGCTACCTGGAGCGCGTGCTGAAGATCACCATCGAGCCAATCCTGCAGGCGGCAACCGCCGGTGCTGGTGGTGGCAACCGCATGATGGTCTACACCAAGAATCCGCAGTTCGCCAAGTTCCACCTCCCAATGCCTTACACCCTGAATGCGCCGATCCCTGCGCATGGCGGTCTGGTGTTCGAGGCAGCAGGCGTGGTCCGCACCGCTGGTACCGAGCTGCGCGTACCGGCATCCCATCTGTACGTCGACGGTATCTAAGGGGGTTACATGGCAACTCTGACCAATGCCAGCGTTCACCCGCTGGTACTGGCTGATCTGACGATCCAGCCAGGCGAAGTGATCGAAGACTTCGACGACAAGGCCGCTGAAGAGCTGAAAGACAGCCTGTTCGTCAAGGCTAAATGGCTGAAGATCGAGCAGGCACCAAAGCCTGATTCGAAAGCCAAGTAAAACCGATAGCCCCGCCCAGTGCGGGGCTGTTGTTTTCTGGAGGTTGCACCGTGGCTGAACTGACCATCGACGTGACGCCGGCGATCATTGCTGACTTCCGAGCGTTCTACGAAGAATTTTCCGACAGTGCCGCCTGGTCTGATTCCAAGATCACCAAGGCGCTGTACATCGCACGCGGCGAGCTCGATGCCTGCCGCTGGGGCGACTACAAACCCTATTCGCTCCTGCAGCGCGGATGGTTCGCCCTGGCGGCCCATTACCTGACCTGGAACACGGCAACGACCGACGCCACTACGGCAGGCGGCAGCGCCTCGACACCCTACGCGGTGGCCAGCAAGGGCGTGCGTGACGAATCGGTGTCCTACGCCATCCCGGCGGCGAACGCCAACCTGACGACGTGGGAAGCGGCTCTGGCCCTGACTCCCTACGGCGTCGAGTACCTTCACCTGCGGGGTCGGGCCGGTATGGGGGCCGTCTGCGTATGATTCGGCCGACCGTTAGCCTGATCGGCAAGCAGCAGGTCGAGCAAGCGATGAAGCAACTGGCCAAGAAGCTGGAAGGTGATGCTCGCGTGCTGGCCGGCGTTCCGAAAGGCGCCGGCACTTACGAAGACGGTCTGACCCTGGCGACTATCGCGGCGGTCAACAACTTCGGCTCTGCTGACGGCAAGATCCCTGCGCGCCCCGTGCTTGGCCCGGCCATCGAGAAAGGCACCCCGCAATACCTGCGGCTGGCCGAGGTGATGATTCCCAAGGTGCTCAGCGGTGAAATGACCATGAGCATTCTGCTCGAGCAGATGGGGCAGCTTGCCGAGGGGCACATCAAGCAGGAAATCACCGACCTGAAGGATCCGCCCAACGCAGCATCGACGATTGCCGGCAAGGGTTCCGACAACCCGCTGATCGACACCGGCGCCTTCCGCCAATCCATTCGCTACGTCATCGCCGAGGCAGGCGACCCAATCGAAGAGGGCTTGTGATGGGCTTGAACATGCGCGGCCACGTCAGCGGCCCCTTCGTGACGCACAAGGGCGTTGTCCTAAATCGCTACACCAGCGAGGTCGTGGACTTCGAACCGGTCCTGGCCCTGACCTACAACGACACCTTCAACGCGAACGTGCAGCCGGTCAGCGACAAGGAAATCGAATTCCTGCAGATCGGCGCCGAGCGAATCAACGACGTGCGGGTGATCCACCGCAATGACGGCAAGGGCATCGAGGTTTCGACCCCAGGCAAGCTTGCCGACATCCTGGTGTTCGCCGAGACGCCAGACAAGCCGGTCACCTGGTGGAAGTCCATCGCCACTGATTTCAGGCCCTGGCACAACTTCTGCCGAGCTGTGGTGGCCAAGCTGGACCCGGCCGAGATCGCCACTCTGGAGGCGCACACCGATGCTTGACGAAAAAGCGCTGTCGAAGGCTGTGTGTCGCATCGTTGTAGCTGCGACAGGCCTTCCGGCCAACAAGGTGATCCTCGCCGACAACAACACGGCGGCCCCTGCAGGAAGCTACTGCGCGGTACGCCTGCAAAACCCCGAACAGTTCGGCCAGGCGCTCAACTCGCAACGCAACGTGCCGGCCGAGGATGACCCGCAATACACGGACATCATCGCCAAGGTCGCCACCCAGTTCACCCTGGGATTCAGCATCAACTTCTACCGCTCTGGCGCGATGGGTTACGCCGCAGCGATCTGCGAGGCGAATAAGCGCGAGCCGATAAAGGCCCTCCTGCGAACCGCAAAGCTGGGCTGGTCCCGCGTATCACCGATCAACAACCTGACCGGGCTCTACCAGGCGGCGATGGAAGAGCGCGCCCAACTCACCCTGTACCTCTACGGCGAATCGATTGCCGAAGACCGTGTGCAGCGCATCTATCGCGTGGGGTTCTCCGCGCAAACCGAACAATCTGGCGCCACTGCGCAAGGGGAAGTAAATGGCTTATCCGGCTGAAAGCATCATCAACATCACCACGCTGATCAACTCAGCCGGGCTTGGGACCTCCAACTTCGGCGCGGGAATGGTGTTTGCCGACTTCGATTCGTCGAGTGACGCGACCTTTGCTGAAGGCTCGTTCCGTGACTACGGCTCGCCATCTCAGGTGGCCGCCCAGTTCAACATCGCCTCCGACCCTTACGCCGCAGCGCTGGCATGGTTCTCGGCGGTACCGAAGCCCAAGACCCTGCGCATCTACCTGCGCATCGAGGAAGACACCCCGGTCGAATCGTTCAATGACGCGATCAACAAAGGCATCTGGTTCTATTGGTACGAGTTCGAGACATCGATTCGTGCTGACGATGCTGTTGTGCTGGCCTTGGGTGCCGCTGGTGATGCCGCTGGCAAGTTCTTCGCGTACACGACCAATCAGGCGACGGTGCGTGATCCTGCGGCCACTACCGACATCGTTAGCAAGGCCGTGACCCAGGGCTCGCGCCGTATGCTCGTGGCCAGCCATGCGACCGAACTGTATGAAGGTTTCGAGATTGCCGCCGTGTTCAGCCGCGTCAATTTCAATGCAGCGAACTCGGCCATCACCGGCGAGTACAAAAAGCTGCCGGGCATCGACGCCGAAAGCCTGACCCCTACCGCATACGGTGCCATGAAGCAGAAAGGAGCGGTGTTCTACACCGTTGTCGAGACTGGCGGCGAAAGGGACGCGGGGCGAATCATCAACTCGAAGACCACATCGGCCAACGGCGAATACATCGACGACGTCTTCAACCTGGACGCCTTCACCAACGTCATGACGGTGGCCCTGTACAACGCGCTGACCAAGGTTCCGACCAAGCTTCGTCAAACCCCAGCGGGCCAGCAGGTCCTGATCGACGCTGCCGCTCAGGTCGGCGAGAAATTCATCGGCAATGGTTACCTCGGCGAGCGCCTGTACATCGACGAAGAGACAGGAGAAGAAAAACTGAGCCGCGGCTACCAGATCCTGACCAAGGCTGACGACATCCTGCTGATTTCGGACGCTGAGCGCGCTGCTCGCGGCGCTGCGCCGATCGTCATGCGCATCTTCCGTGCCGGCGCCATCCACACCGTCGACCTGACGGCCAACGTTGAATAAGGGGCGCTAGAACATGGCACTGACTGATCTTTCTGTAGAAAACACCATCGTCGTCATCACCACCGTCGGCGTGATTGACGACTGGGGCCGCACTGACCCGCCCTTCACCGTGGAGCAGATCGACGACAAATCGACCCTGAGCCGCGGCCTGGGCGGGAATGCGGTCAAGTTCACCCGCAAGAACCCGGGGCTGCGCCTGACTCTGAACCTGATGCCGGGGAGTCCGCAGGCTATCGCCCTGCAAGCCATGGTCAATGCTGGCACCGAAGCGTCTGGTTCATATGCCTCGATTGCCGGCCTGGAGGGTGCCGTATTTGCTGAAGGCGTGTTCACTCGCGGCAAGTCGATGGCGCGCGGCGGTCCAGGTATGAACGACGCTACCTTCATCGCCGAGTTCAACAAAGAGGCGATCGTATGAGTGATGCCGCATCGCATATCCGCTCAATCGAGCATGACGGCGTGACCTACCGCTTCGCCATGCCCAGTGCAGAGAAGCAGCGCGCCGTGCTGTTCCGGCTGGGCAAATACGGCGTCGAGCCGATGATTCGCGGGCTGGCCTTGGCCGAGGTTGGCGCGGCGTCGTCCTTCATGGTTGCCGGCGGCATCGTCGGTACCATGCTGTCGCGCATGCCCGAAGATGACTTCAACTTCGTCTGCGACTCCATGCTGGGCAAGCTGTTCAAGGAAGGTTCAGCCACCCCCGTGACCATGGAAGACTTCTCGGGCCGACTGAAGACCTACTTCACCCTGGTGGTGATGGCTCTCGGTAACGTCTTCGAGGATTTTACCGGTCTCCTGACCCTCTTCCAGAAATCTACCGATTCAGCCGAGGTGGTGGGTTCGAGTCAGGAGCCCGGCTAAACCCGGCGGTCGACTGGGAGCTGTGGCGACCATGCACCGGCATCCCCGGCCTGTGCCCGCCACTATGCACCTACAAAGACCTGCAGGACGGCACCTATTCGCTCGGCTGGGTCAAGCGGGCGAATCTGGTCATGGATGAAATGATCTACGCCCGCCACCTGGCCGAAGCCAATCGCCAAAACTAGCCCTGCACTCGCGGGGCTTTTTTATTTCAAGGAGTCGGCCGTGAAGGTCTTGGAATCGTTTCTCATCGCGCTCGGCCTCAAGGTCGACGAAAAGTCGTTCCAGGCGGGCGAGACGGCGTTTGGCAGCCTGACCAAATCAGCCCTGCAGCTTGGCGCTGTGCTGGCGAGCAAACTGGCCATCGACAAAGTGGTCGGCGACTTCAAAAACGCCGGCACCGAACTGAACAACTTCAACAAACTGACCGGGCTCAGCACGCAGAACGTGCAGGCACTCGGTCAGGCGCTCACGGCTCAAGGCGGTAGCGCCTCGGACGCCTTTGCAGCCATGCAGAAGATGCAAGATCTGATGGCCTCGCCAATCACCGGGAACACCGGATGGTTTGGTGACGTGGCAAAGCTTGGGCTCAATCCCGACGCCATCATCGGCGCGCAGGACACGGCCGAGGCAATGGCCAACATTGCCGGCGAGTTCGAGCACATGAGCGAGCTTAATCAGCGCCTGGCTGGTCAGGCCCTGGGGCTGGATGATTCAACCGTGCGCCTGCTGATGCGCGGCCGTGACGAGGTTGAAAAGCAGCTGGATTCACGCGGGAAGCTTGCCGTGATGACCCAGAAGCAGATCGACGATTCGGCCCGCCTGACCAAGGTGAGCAGTGAACTGGACCTGGTATTCACCGACATCGGCAACACCATTGCCGACGAGCTGGCACCGGCCTTTGCCGACATGGCCGAGGACTTCGTCGCCTTCTACCGCGATAACAAGGACCTGGTCGACTCGGGACTGAAGGAGTTCTTTGGCGGCCTGGCCGACAATATTGAACTGGTATCGATCGCCATGGCGTTGTTGGGTGGCGGTGCTGCACTCAAGGGCTTGGCGGCGTTGCGCGCGCTTATCGGACTGGGTGGCTCTGGTGCAACTGCTGGTGCTGCCGCGGCGGCGGGTGGGGCCTCTCTGCTGGCGGTTGCCGGTGGCAGTGCGGCGGCACTGTTCTATTCCCGCAAGCTCAACGAGAACGAAGACATCGAGCTGCTGAATAACAAGCTGAAGAAGGGCGGCACGGAAGCGGCTGGCGCGACAATTGACTTCTTCAGGTCCAAGGGGTGGACGGAAGAGCAAGCGATGGGCATCACCGCCAACATTGAACAGGAAAGCGGCTTCAAGCATGACGTTGAGGGTGACGGCGGCCAGGCTTACGGCTTGGCGCAGTGGCATCCAGATCGTCAGGCGGACTTTGCCAAGTTCTCCGGCAAGGACATCCGCCAGGCCTCGGGCGCGGAGCAGCTTGAGTTTATCAATCACGAGCTCACTCGCGGCAAAGAGAAGGCGGCAGGTGAAAAGCTCCGGGTGACCTCTACCCCTTCCGAAGCGGCGGGAGTCGTATCGAAATACTACGAGCGGCCTGCGGATCACGAAGGTGAAGCTGAGCGTCGCGGTGAAATGGCTGACACCTACGGTCGCTCAGCCCCTAAAGACACTCAGGCATCCAGTGCGCCGGCTGTTGATCTAAGCGACCCCGTTGTTTGGGCCAGGGTCCAGAAGGAGCTGAAGCAGTCTGGAGCGCCGCAAGAAAGCATGCTGGACCAAGCGAAAACATGGCTTGAGTCTCATCGAAAGACGTCTCAACCCCAGCCGGCATACGGCGCGGCTGAAGCATGGAATCCAGCCCAGCGTGAAGCGCCTCGGGAATACACGGTGAATGCGGTTGTTCAATCATCACCCCAAGCGCCCATCACTCCGGCGCAAAGTCAGGCGGCGCCGACTGCCCAGCCATCCTACGTCGACAACCGCCAGTTCAACATCCACGGCGCCGACACCGAGAAGGTCAAGCAGCTCTACACCGAGCAACTGAGCAAACTCACCGAGCAAACGATGCAGGACTTCAGGAGCCCTGAAAAATGAGCCTGATGAGCATCTTTACCAAAACGCTGCCGAAGATCGGACCGCTGGAGTTTGACGCCAAACTCGAAGGGGTAACCAGCAAGTCGGTATACCTCACGCAGTTTCCGGTCGAGTTCGGCGCCAACATGAACGACCACGCGATCCTCCTGCCGAATCGCTACCTGCTGACGGGGGCTGTCTCAAATACCCCTCTCGGCCTGGACCTGAGCGACATTGGCATGATGGGCGTTGGCGCGGTGGCCACTGCGGTTGGTGGCATTGGTGGCGCCGCGATAAGCGCCGTCTCTGCCTATTTGCTGTCAGGCAGCGAAGAGACCAGGGCATCGACGGCCTGGGCATCGCTGACCGCCATTCTGGAAGCCCGCGCCAAGTTCGACCTGGACACTGGCAAGGAAATCATGCGCGACATGATGCTGATCCGCTTGGACGAGCGCACGCGCCCAGAGAATGAAGACGGCCTGGTGTTCATTGCCGAGCTTCAGCAGGCACGCATCGTCCGCTCGAAGGTCGGCCAGGGCGTCACCTCGGCGGATCAGCTCATGAAAAACGACACCGTAACCACGCAGGGCGCGCCAATGGTCACCACCGGTGAAGCTTCGGTCGAGGTGATCCGATGAGCCGATACAAGGTAGCAATCCAGGCATTGCCCGCGCAGACGTTCAGCGCTCGACTGGGAACCAACACGCTGACCATTGAACTGCAATGGATGGCCCGCTTGGAGGTGTTCCGCGTGAACATCCTGACCGCCATAGGCTCAACCCTGACCGCTGGGCGCTTTCTTCTGCCTGGCGTCGACCTGCTCGCCGGCCTGTATCCGCCGCCAGAAATCACTTACGGCTCCCTGACGCTGGAGGGAGAGCAGCCGACCCCTGAAAACCTGGGGGTCGCCAACTTACTGGTGTGGTCCGATGAGTGATGAACTGTTTCTGCGCAGCTACCGGCTGAAGGTTGGGCGGGTCACAGGTTCGCGAGTTTACGAAATGCGGACCGGCGAGATTGTCCCGGGTGACAACGACGGCCTGCGCATCACCTTTCAGGCCACTCACTTCGCCGGCAATGCGCTCAGCGTGGCCGAGATCACCATCTACAATGTGTCCGCCTATGCCGAACGCCAAATGCTCGGCGATGGCGTCACCAAAAAATACGAGTTTATTTCGCTGGAGGCGGGCTATGCCGGCCAGTTTGGCGCGGTATTTGTCGGGCAGATCGTCAACGTGCAGCGGCATCTGGAAGACGGAGGTGCCACTAAAGGCATCCGTTTCTTCTGCAAGTCGTCAGCCAAGGAGCGCGATCAGAACCTGATCAACCTCACCCTGTCGCCTGAAACCGACCCGGTGCAAATCATCGAGGCCTGCGCCGAGCCGTTCGGGGCGGAGATCCAGTTCTACGGCGACTTCTCCGAACTCAAGCGCCGATCGCGCGGCACCGTCCTGCAAGGCAGCCCCACCGCCTGCATGAACGAACTGGCTGAGGCATTCCAGTTCGACTGGATGGTCGAGAACGGCGCCCTGAAGGTTATCAAGCGCGAATTCGCCCTGGCTAACCAGGTGTACGTCATCAGCGCCGGCACCGGGATGATCGGTTCGCCCGTGGTGACTGATACCGAAGTTGGCATCCGCTACGCGCTCAACCCCAAGATCAAGCTCGGCGACACCATCAAGCTGGAATCGATGGCGCCCCGTTTCGAGTTCTCCGGGGCGTTCTTCTACGACATCCCCCGCACGATTGGCGAGGGCTTCTACAAGGTCAACTCACTGGTGTTCGCTGGGGACTCCCACGGCGATCAGTGGGAGGCCCAACTCAGCTGCCTGCGCCTCAGTGCGGCGGCACAGGCCGGTATTTCCCAAAGGGCTACCCGATGACTGATCCGCTCGCCTCAAGAACGCAGGCAGAGTTCACCAAGATGCTGCGCGGCGTTTTTGGCGAGTACCTGAAGGACAACATGCACACCAGCGTTCCGGGGCATGTCCTGAGCTTCAACCCAGTGACCCAGCTGGCTGAAGTACAGATAGGCTTGATGATCGAGGATCACCAAGACAATCAGGCAGCGCGCCGGCCAATCATCTGTGTGCCCGTGCAGTTCTGGGGTGCCGCTGGTGGGACGCTGGAATGCCGTGTTGCCAATGGCACCGAGGGCGCTCTGTTCTTCTCTAAAGAGTGCATCGACTCGTGGGTCGATCAGGGCGGCGTAGCGATCAAGTCCGAGCCGCGGCGATTCTCGATCAATGACTGCTACTTCATCCCTGGCATCCGCTCGATCCCTGGCGCTATCACCAATTTTGCCAACGACGGCATTCGCCTGCGCAGTAATGACGGCTCGGCCTACATCTGGATTCACGACAACAAGACACTCGAATTCGATGGCGTGTCGGCAAATTTCAAGTGCCCAGTCAATTTTGAACAGCCGACCAACTTCGAGCAGGCCGTCACCACCGAGACCACCATTCACAACCAGGGCGTCAGCATCGGCCTCGAGCACGAACACATCGGTGTTGAAGTTGGCGACGACATATCAGGACCGGTGAATCCATGACGGTACGCAAATTAGACACAGACGGTGACCTGGCCATGGGTCCACAGGAATTCCTGACCGGCTACAGCGCCGAAGAGGTCGCGCAAAACGTGCTGACCCGCCTCAAGTTCTTCCTGGGCGAGTGGTTTCTCGACACCGCCGACGGTACCGACTGGTTCGGCAGCGTCCTTGGCAAAGGCTCGGCACTTGCATCGCGTGAGTCGGTGATTCGCCGCCGAATCCTGTTGACCCCAGGCTGCGCTGGCATGACGGCCTTCAGCATGACCACGGACATTGCTACGCGGCAACTCACCGTGAGCGCCTCAATCGTCAGCAGCTCAGGCGACAGCGCCGAAATCAATTATGTGCAGGCGGTTATCTAATGGCAGAAATCACCGATCAAGGCATCACCGGGCGATCGCTCAACGAGTACCTGGCCGACATCAAAACAAGAACGCTGGCGATTGATCCGAACTGGAACATCGACCCTGACTCGCCGGACGGTCAGCGCATCGGCATCGACTCCGAACTACTGACCAACCTGGACGAGGCTGTCATCGCTGCCTACCGCAGCAAAGACCCCGACAGCGCAACGGGCGAAGCCCTGCGCGACATCGGCAAGATCTCTGGCGTGCCGATCCGTGATGCGACCTACTCTGTCGCACCGATCACCGTGGGTGGGCCTGCTGGAGTCGGGATTCCTCAAGGCTCCCAAGTTCGCAGCCGGGTCGATAACACCGTATGGCTGACCACGGCCGCTATCGTCATCGGCGTCGGCATGACGGCCACAGGGTTTGCCATCTGCTCAACCCCGGGCCGCGTCTTGGCGTCGGCCGGCGATCTGACCATCATCGGCACGCCGTTCCCGGGCTGGTCATCGGTCACCAATTCCGAAGCTGCTCCAGGCGACGACGCCGAGTCGGACGAGGAGTTTCGTGCGCGTCGCAATCGTTCGGTTGCCCTGGCCGGCAGCAACATGCTCGACAACATGATCGGCAATATCGCAAACGTGGCCGGAGTGACTGACGTTGTAGTTCTGCAAAATACTAGCGTCAACCCATTCGACGCTGACGGGGTTCCCTATTGCGGCATCGCGGTTATCGTCAACGGCGGGTCGGATGCTGACATTGGTCTGGCCATGTATGAGAAGCACAACCCGGGAACGCCGATGTTTCCGCGCTACAACACCAAAACCAATACGTGGGTGGATGCACCAGGCTCTAGCGGCGTCAAGGTCGACGTGACGTCTCCGGTCACCGGCAATCGAGCTGTTATGACATTCCAGCGCGCTGTCGGCCTGGCGGTTTACGTGGCTGTCAACGTGAAGAAAAAAGGCGATCTTCCAAGCGACATCGCCGCGCAGATTCAGCAGGCCATTGTGGCCGACTCTACGAAAGGGCTGTTTTCCGGCGAATCAACGATCGGCTTCAACAAAAACGGCTATGACATCGGCGAAGTGGTGCCGGTGGGCCGACTCTATACGCCGGTCAACAAAGTGCTTGGCAAGTATGGCGACAGCTACATCGTCACGCTGACAATCGGCCTTAGCGCCGGCGCACAGGGATTGACGCCAATTCAACCTACGATTGCCCAGCTCGCCACCTTTGATGCCGGCAATATCGCAGTGACGGTGACGCCATGATCATGGATCACGTCGCGCGAGCCAGGTCGCGCATCATCAACGAATACCGAGACAAGCCACGCATGGAACGATGGCTAACGATAACGCCCGAGATCGCCAATAAGCACCTTGAGTCGCCGCTGAGTCAGATCTACGCCAGCTATGACGTAGACACCGTAACGGGCGAGCGTCTAGACATCATCGGGCGAATCGTTGGGATGCCCAGGCCAATTCTGCGCGGCGCCGCGTATGACGTGTTTGGCTACGCAGGCAACGATACCTACACCAACTACAACATCTCGCCCTATATCGGCGATGGCGCCATGGTTGACGCGCCGCTGAACAACGATCTGTACCGGAAGCTGATCAAGGCCAAGATCGCCCGCAATATCAGCGACGGCACCGCAGACAGCATCATCCAGCTGGTCGAGATGATCATCGATGTCAAGGTGACAGCGCTGATTGATAACGGCGACAAATCATTTGATATAGGCATCGCCTCGGAACTAGACAATACGACCGAGTACCTGCTGAACAACTTCGACATCATCCCGTGCCCGCAAGGCGCGCGCCTCAACTCGATATTCGTCCTGCCGACCAACATCAGCGAGATCGAGCAAACCTCGCTGCGCGTTTACACCTTCGCAAACGTCACCCTCCCTGGAGATTTAGCCTGATGGCAAGACAGCCTTTCAATACGCGCTGGGCTCAGGGCGTGGAAACCGAGGACAGCCTTAACTCTTTCAAGGCTCCTGGCGATGTTCGCCTTTCAACGGGCTGGGAGGGCGGACAAGACAAGGATGCGCCGCCGGCCGGCCAGGAAAACTGGTGGCACAATCGGGTCGATAGCGCACTGCAGGATCTGGAGCGGCGGGGTGTCATGACCTGGCACCCTCAGGCGATATACGACAAGGGCGCGCCATGCTACGCCGATGATGGCTACTACTACGAGTCGCTTTCAGACCTTAATTCCGGCCATAACCCATTGTCCAGTTCGGCCTTCTGGCGTCAGCTTGGCCAGTCGCTGTACTCGAGCTTCAGTGTCGGCGAGTACAAGGATGTTGCGCACAACGGAACACCCGACTCTGGCTGGCTCAAGTCAAACGGCGCGCTACTGTTTCGCACGGCGTACCCGAAGTTGTTCTCAAAAATTGGAACAACCTACAACGTCGGCGGCGAACTGAGTACGCAGTTCCGTCTGCCGGACTGGCGCGGCGCCTTCCCGCGCTGCCTGGATGACGGGCGCGGGATCGATGGCGGCAGAGGCCTGAACAATACATTGCAGCCCAGCCAGAACCTTTCGCACGCGCACTCAGCCAGCAGCTCGAATGTAGGTGATCACGCTCACAGTGCTAGCAGCGCTGGAGCTGGCGGCCACGCTCACAGCGCTAGTAGCGCTGGAGCTGGAGGGCACACGCACGACACCGCAATCAGTCGCGAGCGAATTACGGCAGCCTTTGTTCCGTCAGGCGGCAACGCAGTGTTTGGCGACCAAGAAAGCGATGGCACGAATACCTTCACTAGCTCCTCGGCGGGCAATCACGCTCACGGGATCACCGTGGATGGCGTAGGCGATCACGCTCACGGGATCGCTGTTCAGCCGGCCGGCTCGCACAGTCACACGATCAGCATCGGCTCCAATGGCGGCGCCGAAGCCCGCTCAACCAACCTCGCGCAAGTTCGATGGATTCGATACCTATGAGCCAAAAGACGGTTTATCAATACGACGCCAGTGGCTGGTACATGGGCGAGACGCTGGCCGATGCCGACCCGGTGGTGGTCGGCAATTGGCTGCTTCCGGCCCGAACCACTGAGGTCAAACCACCATTGTTCACCGGCGGCAAGATGCCGAAGTGGGCCGGCTACAAGTGGAAACTCATCAACCCGTAGGTGTAGATATGGAAAGACCTCGCAAGCGCCGCTTCACCGACAAGATGGAGGCGTTTTGCCTCGTCTACATGGAGACGAACAATGCTTCTGAGGCCTACCGTCGTTCCTACAACGTCACAAACATGGCGGACAAGACGGCTGCTCGAGAGAGCTGGATCGTCCTGCAAAAGCCGCAGGTTCAGGCCCGGATCGCCGAGCTAAGGGAAGCAGTCATGGATAGGCACCAGATCACCGTCGATACGTTGCTGGCGGAACTGGAGGAGGCGCGCACGGCCGCCCTTGCTGCCGAGACACCTCAAACATCGGCCGCCGTCTCGGCCACCATGGGCAAAGCCAAGCTGCTCGGCCTGGACAAGAAGATCGTTGAAATCACCGGCAAGAATGGCGGTGCTATCGAGACGAAGTCCCGCGTCACGGTCGACAAGAAGACCCTCGAATCTGTGCTCGATCGCCTATGAGTGCGCTTCTCGACTGGGATTCAATGAGTCGGGAGGAGAAGGAAGCGTCAAAACTGATCAGCGAGCATTCCCCGCTTGCCTTCATGCGCGTCTTCTTCCAGATTAACCAGGGGATGAAGTTTCTTTGCAACTGGCACCACCGCTACATGGACTACACGGCCAAGCAGGTTCTGGCCGGCGAGCTCAAAAACGTCGTCTTCAATATGCCCCCAGGCGGCACCAAGACTGAATACTGGTCGATCCACCTGCCAGCCTACGTAATGACCAAGTTCGACCGTACGCGCAACCTGAGCGTGTCCTACTCCAAATCTCTGGTCGAAGAGAACTCCAACCGCATCAAGTCGATCATCACCAGCTCCGAATACCAGGAGCTGTGGCCCTGCGAACTGGGCAAGGCCGACGTGGCCAACTGGATCATCACCGACGAGAACGGGCGCAACAAACACCAGATCTTCAGCCGCTCCACCGGTGGACAGATCACTGGTGTGCGTGGCGGCTATATCTCCGAGGGCTTTACTGGGTTCATCAACCTGGATGACCCGGAAAAGGCCGACAGCGCATTCAGCGCGACCATGCGGGCCAAAGCCCAGCGCATTGTCACCAATACCCTGCGCAGCCGGCGCGCCTCACCTGACACGCCAGTGATCTGCACCCAGCAGCGCCTGCACACGGATGACGTTTCGGGCTTTCTGCTCAAGGGCGGCATGGGCCTGGACTTCAGCCACATCAAAGTCCCGGCCCTTGTCACCCGCGACTATATAGAAGGCCTGCCCGCAGAGATCCGCGAACACGCTGAACGTGACGTTTTTAGCGGGCCCTCAATCGTCCGTGGGGGCGTCGAATACTGGTCCTACTGGCCAGCCAAGGAGACGGTCGCCGATCTGATGGCGCTTTGGGATCGCGACCCTTATACCATGGTCAGCCAGTACCAGCAGGAGCCGGTGGCGCTGAGCGGCGGCATGATCGATGCCGACTGGTTCAAGACCTACCAGCAATTGCCTTACCTGGTCTGGCGCGGAGTGTACGTCGATACCGCGCAGAAGACCGGCGAGCAACACGACTACTCGGTTTTCAGTCATTGCGGCCTGGGTGTCGACGGCAACCTGTACATCATCGAGGTGTACCGCGGGAAGTGGGATGCTGGCGACCTTGAGACCGAAGCTCTGCGCGTTTGGCAGAAGTGGAAGGATTGGGATCAGTTCCGTCCGGCAGCTCTGCGTTACATGCGTGTCGAGGACAAATCGAGCGGCACCGGCCTGATCCAAACCATCAGCAAGAAGGGTGGGATACCGATCGAGGCCCAGCCGCGCGGCCCGGCGGCCAACAAAGTCACCAGGTGCATGGATGCTGTGCCCTGGCTCAAGTCGGGCCGGGTGTTCGTGCCAGCCATCTACGACGATCAGGGTTGCAAGATTGAGCACGTTCGCGACCACCGTGGCGAGATCGTAGCCTCCACCGATTGGGTTGCGCCTTTCCTCACAGAGGCCTCGGCCTTCACGGCTGACGATACCCATGCGCACGACGACCAGGTCGACACCATCTTCGATGCGGTCGCTGACATGTTGATCAGCAATGGCGGCGAATTCTTCTCCAGTAACTGGCTGTAACCCCAACCGAAATCTTTCGCGGACCAAACCTGGTCGCGCTCATTAAATTCGCCCCAAGGAAATACACATGGCAGACCAGACCCAGCGGCTAGATATTGCCACGGTAAAGGCTGAGATCGGCAGCGATATTCTTTCGCGGTTTTCGAATGACGCGGTGACGGCTGACCCTATCTCTACGGACTCGGGCACCATCCCGAACCTGAAACAGGTCATCGTCAGCATCCAGGAAGGTGGCGCGGAAAAGATCAGTTTCGCCTCGACCATTTACTCGACGACCGCCGCCGGCATCGCTGCAACCACAAACGGGGCGATCTTCCTCGTGAAGTCTGATGAGGCTGACGAAATTTATGCTGTATGGCAGAACTCCAGCGGCGTAGCGACTGATACCGGAAAGCGCGCCATGGCGGCGCAGGCAATTCAAGATGCCATGCAATCCGCAACGGAGGCAGCACAGGCAGCAGAGGATTCCGCTGATCTTGCTACGGGACGAACCGCTCGCTTCCTAGTGTCGGTTGCTACGCCTCCGGTCATCCGCGACGACGGCACGCCTTTGCAGCTTGGCGATCGTTACGTCAACACCGAAAACCAGGCTGAGTACATCTATAAGTCGTCCGGCTGGATTGTGAATGAAAGCCTTGAGGCCATTGCGGCAATCAAGGACGACACCGATCCAGCCAATGGCGCGGCGCAGGTTGGCTGGGACGGAGAGACTGTCGGCGCCCAGATGAGCCTGTCTAAGAAGATTGCGGACTATGCCGCGTTGCGGGTTTATACAGGCACAGCAACTGGCTTTAAAATCACCGATGCCAACTTCTCCGGCAATTTCATTTTAGATCCTTCTGACACGGTCTCAGCGGATGACAAGTCCACAGTCATTGTTGGGGCAGCAGGTCGCCGCTATAAAAGGATTTATGATGGAAGAATACAGGCGGCATGGTGCGAAGGTGCAAGCGATTCTGCAATAATACAGGCGTCGATTGATGCCGCTCTGCGCGAGGGAAAATCAGAAGTAGGCATAGACAGGGATTACATCTGCGATACTGCGCTGACAAATCGGACCAATATACGGTTTGTTGGGGCTGGATCGTTATCAGGGGATTCCTGTTATCGAGTGAGAGTTATGCCAGAATGGGCGCCTACTGGGCGTGAGCCTTTCCAAGATCTGATCCCTGCTCAGCACCTGCGTGCCTTCTCAGCAGCTCCGGCACCCACCGTGGTTATCGTCGGAAGCTCTACAGGTGGATGGGCTGCCGACTCTATCGACACTGGAGGCGGTGTCACGCCAATGCTGCAAAGATTGCTTGGCAAATACAATCCAGAAAAAAACATCAGCTTTTATAACCGATGCATTGGGTCTCAGACCTTCGCAGCCCTTAATAGCAAGCCAACGTCTTTTCCGTCCTGGTACACGGACACCGGGCGAGACTGGCTTCAGTACATCGCGGATCTTGCGCCAGATACCGTGTACATCATCTGCGGGAGTAACGACAGCTCTTCGGCAGAGCGCCCCGTCATCAAGTCCATCCTTGATAAGTTGGCTGCGTTCGCCAAGTCGCCTGATGTTGTTTTCTTCACACAGCCGTCAGTGTGCCCGGACCCTGACCCAGCTTTTGCATCGAGCGGAACACGCGCCAGTCAAGAAGGTCGCGACTACGCTGCGGGTCTGGTTCGTAGTATGGCGCGGTATTACAAGAAGGGTCTGATCGACGCCAACCGTATGGGCGGCATCGTGCTGGATGGACGCGACATTCTCGACAATGCGTCGATGCGCATCCTTCCATCAATTCCGGTTACATCGGGTCGATTCGCCCCCGGTCTGTCAACGATTGATTTCTCAATGAGCCTTAATTTCAACGGGAGCGCCGCGGCCAATGACGCAGCGTTTCTCGTTGGCGCCACCAACCCTGTTTTCGTCAAGACGGGGGCGGTCGGCGCGAACTCGGACTCGGGGGATATTGCCTACATCCAAAAAACCGCTGAGGGTTTCCTAAGAGTCCAGCTGTACAGCGACGGCCTTTACCAGACGCTCACTACCGGTGTGGTATTCCCTACAACATCTTTCACGCTGGACGTGATCAAGGTTGGCAACGTACTGACCTTGAGCTTCAATGGCTCGGAGGACATAGCGCGAGTCAGCTTCAACATCATCGCGGCGGGCGGCGAGATGTATCCGCGAACCGGTTACTACAACCTGACTTCTGGGCCGTGGACGTCGGTGGTACTCAACGTTGGCCTGCCAAAGCTGTACAAAAAACTGCTTACCTCGCAAGAGGCGTGGGGCCTGCCAAATCCTGCGGCGTCGCGGCAGATGCCTTACGGTGGCAACGGTTTGAATCACCTAAGCAGCCTGGGCACTCGCGAGATTTACGGGCGAGTCATGGACACCCCGGCGCTGAGGGGTGTGAACACGGACTTTGGAGAATATAGCCCTGGGCTTACCCCAGGCACTGGGACGCCGACAGTCACAGCGCCAGTAACCTGGGCGTGGACGCGAAACGGGAATATCGTGCATGTAGACGGCGTAGTGTCCGTTTCGCTGGCTTCGGGGAGCACCTGCTCGTTTTCGGCAACACTGCCAATAGTCCCTGCCGTTCTGAATCAAGACAAGACTATCGCCTTGATAATGTCAACCGGTGCAGGGCAGACAGGCGCCGGCTTTGGCGATCCAGCCAACAAGGTTGTGCAGATAACGCTACAAGGAGCATCGCCGACAGCTGCAAAGTACCGCGTGATGCTCTCTTATCGGCTTTCCTGATTGAGGCTGACAGGAGGCCAATCGTACAAAGTGCCTAGCTCGATTTGACCCGCCGCAACAACCAGCCGCCTTAAGCGGCTTTTTGTGCCTGAAGAATGCCCGCCACTGCGCGGGCTTTTTCATGCCTGGAGAAAAGGAATGCCCATAACCCAGCAGCAACTGCTGCAGATCCTCCCGAACGCCGGCCCAGTTGCCGGCGTTTTTGTGTCCGCGCTAAATGGAGCGATGGCGCGCTTCAATATTCAAGGTCGGTTGCGTGTTGCCGCGTTCCTGGCGCAGATCGGTCATGAGTCCGGCCAGTTGCGCACCCTGGTCGAAAACCTGAACTACAGCGCTGATGCTTTGATCAGGACTTGGCCGAAGCGGTTCAACCTGGTGACGGCAACCAGTGTTGCTCGCAAGCCCGAGAAGATAGCGAACATCGTCTATGCCTCGCGCCTGGGCAATGGGCCTGCCGTGACAGGCGATGGTTGGCGATATCGGGGTAGGGGGCTGATTCAGATCACCGGCTGGGTTAACTATCAGGCGTGCGGCTCGGCCCTGAGCCTGGATCTGCTGGCAAAACCGGAACTCCTGGAGCAGCCGGCTTATGCTGCGCTTTCTGCCGCCTGGTTCTGGTCGAGCAACGGCCTGAATGAATTGGCGGATGCTGGCCAGTTCGAAGCGATCACACAACGCATCAATGGCGGGCTCAACGGGCAGGCGGATCGCCTGAAACTTTGGGGTAAGGCGACCGCGGTGCTGGCATTGCAGGCGGCGGTGACGAACCGAACCCCCACCGCTTAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP051487|2486844:2587244|2508870_2509302_+|WP_168757702.1|DBSCAN-SWA
MTPVVMKQFKQKPVRAKSIDREGQEQAALMTELRIRMPDVADLIFHVPNGGHRVKAVAAKLKAQGVKAGIPDLVLPMARGGFFGLYIEFKATPPNDAAISSSQHERIRKLNAQGYLAVVCRGHFDTMEQIRAYLRLAPTVVAA
>NZ_CP051487|2486844:2587244|2549823_2550297_-|WP_168757751.1|DBSCAN-SWA
MPTLTDVGRIGRDAELRYTPGGDAVVNLALACDYGRKGQDGKRPTQWVDATLWGKQAEAMAPYLLKGQQVYFTMDDAHIETYTKTGGGEGFKLTGKIILIKFVGSPPQAANQPQQQSRPQQSRQQAASRPAQNQQAAPPDSFDDDIPFAPLHYLNGA
>NZ_CP051487|2486844:2587244|2502735_2503047_+|WP_168757693.1|DBSCAN-SWA
MAKPKKQSQPVERREISGIERLGLRVSSMINHPVAQTQRWVTIHRLDTDGDREWEEVMGLLSETDGIDMTFNDDESVTLRWEASTEEDRSVAVAEEAEEPAPF
>NZ_CP051487|2486844:2587244|2558479_2558674_+|WP_168757764.1|DBSCAN-SWA
MRRIPLSEFAKQHGHTKAAQMLGCTQGALSKAIRVGRDVFVTLGDDGSLSALEHRPFPSQKSAA
>NZ_CP051487|2486844:2587244|2491110_2493492_+|WP_033042613.1|tRNA|DBSCAN-SWA
MKFSEQWLRGWVSPQVSRDELVARLSMAGLEVDSVTPAAGEFTGVIVGEVLSTEQHPDADKLRVCQVSNGSQTFQVVCGAPNVRPGLKIPFATLGAELPGDFKIKKAKLRGVESNGMLCSQAELQVGEGNDGLMELPADAPVGQDIREYLGLDDASIEVDLTPNRGDCLSLAGLAREVGALYAAPVTRPVVATVAAVHDEVRSVEVLAPAACPRYLGRVIRNVDLSKATPLWMVERLRRADVRSIDAAVDITNYVMLELGQPLHAFDLAEINGGIRVRMAEEGEKLVLLDGQEVSLRSDTLVIADHTRALAIAGVMGGEHSGVNTATTRDIFLESAFFDQIAVAGKARSYGLHTDASHRYERGVDWQLAREAMERATGLLLEITGGEAGPIIETVSEQHLPKIAPVTLRAQRITQMLGMEMDSAEVERLLNALGLTVTADGAGQWRVEVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPQAKAEARSDLPELRRLLVARGYQEAITYSFIDPKQFELFNPGVEPLLLANPISNDMAAMRSSLWPGLVKALSHNLNRQQDRVRLFESGLRFVGQLEGLKQEPMLAGVVCGSRLPEGWAQGRDTVDFFDVKADVEAVLGFAGALDAFSFVPGKHPALHPGQTARIEREGRLVGFVGAIHPELSKTLGLDRPVFVFELVLAEVASGKMPKFQELSRFPEVRRDLALIAHKDVAAAAVLDVIRENAGEWLTDLRLFDVYQGKGIDPDRKSLAVGLTWQHPSRTLNDDEVNSTTQNILTSLEQRLDATLRK
>NZ_CP051487|2486844:2587244|2488784_2489318_+|WP_015095841.1|DBSCAN-SWA
MRQDKRTAPKAPINENISAREVRLIGAEGEQLGIVSIEDALLKAEEAKLDLVEISADAVPPVCKLMDYGKSIFEKKKQIAAAKKNQKQIQVKEIKFRPGTEEGDYQVKLRNLVRFLSDGDRAKVSLRFRGREMAHQELGMELLKRVEGDLLEYGSVEQHPKMEGRQLIMVIAPKKKK
>NZ_CP051487|2486844:2587244|2522880_2523072_+|WP_168757718.1|DBSCAN-SWA
MTTQQHVKPAVGCLVRDPDTYEALPVEGKLVEMNSYWLRKEAAGDIEIVEPAVQDLKLKGDKQ
>NZ_CP051487|2486844:2587244|2494354_2494921_+|WP_168757685.1|DBSCAN-SWA
MPAQSARKTGAKLIEEMSSDRGCMVNVEFSKKHDERFEKHFSSQMDDITLILKCHLMLEEMLRDFCSEMVPQPQFLKDSRFTFAQILDLSRALYPAEIKLGGMVELWSLCEKINRIRNIMAHALDPDSSKLDNHKAAIIEAVRLRGEGNTSALEFVGCLTHVLGAFSLILQVGVTHNNGEDFREIPKK
>NZ_CP051487|2486844:2587244|2506461_2507130_+|WP_168759157.1|DBSCAN-SWA
MSSREIANLTSKQHKDVIRDIRVMRKALSDDGADLRHLREVKDGRDYTAEFHLDRVLTETLLTGYSIPLRHRVVTRLGELENLSRQVVSIPQSLPEALRLAADLADKNGELQLVISKQAPKVAAINRLAAAGGAICITDAAKLLSMAPARLFAWLEQHRWIFRRHGCKRWVAYQPRITSGHMTHKVTALKPDPETGIERAAFDPMVTPKGLTRLAELLQEAA
>NZ_CP051487|2486844:2587244|2540347_2541544_-|WP_168757738.1|integrase|DBSCAN-SWA
MARKTISGLYERNGIWHIDKVVRGQRLQESTGASERQEAEQYLIHRLEKLRQEKVYGVRQVRTWREAATRFLVEFKDQASIGLSASHIEQLDPYIGDLPITHIDDGTLATFKRDRQKPAKTEKGKVKPGVSNRTVNIALQRVVRILNLCHRKWRDAEKRPWLDSVPMISMLEERKSSRKPYPMSWAEQSMLFSEIPDHLLRMSLYKVNTGCREQEVCKLQWDWEIRVPELGASVFLIPADFGGRHEKSGVKNGDERLVVLNKVAMSVIDGQRGLHSKYVFPYGQPDEHGPTPMHRMNDTAWKKARVRAAAKWEVEHKSPAHPGFRSIRIHDLKHTFGRRLRAAGVTLEDRKALLGHKNGSVTSHYSTAELEQLIEAANKVSATDSRGPALTILRRKTG
>NZ_CP051487|2486844:2587244|2505512_2505707_+|WP_168757698.1|DBSCAN-SWA
MNETPLDKFVAEKGQSEAARLLRVTAPAIHKALSVKRDIRVLELPDGSFQAKEQRPFPSQKSAA
>NZ_CP051487|2486844:2587244|2548513_2549254_+|WP_168757748.1|DBSCAN-SWA
MRRSQLKLGVKILKLFQGNAEQLAGLFTSIYISAAIIIVSLRANEIFNLPLNELGDFLAGVFGPLAVLWLVLGYYQQGRELKISSQALVAQCVELSNSVSQQRQALEVSTGQMELAKAKHELEMLEIEESIRPRVDVAYVNSGISNSGEWLNFNFLIINAAAYGLRVCWSDGSAEYEVLTAGYVGAQAREKFQVNFPKNDVDVSFNITVSCKNVRGRPYAYQFTYDSSVGKGLVKAHEPSAPKLVS
>NZ_CP051487|2486844:2587244|2553008_2553203_-|WP_168757755.1|DBSCAN-SWA
MSTAPVKTLIDEQLEGIEQRIAILSFGLPFNEVIGRKREELVANLPQRLAPTMKGGRIAVRIRP
>NZ_CP051487|2486844:2587244|2516314_2516524_+|WP_168757713.1|DBSCAN-SWA
MAFTIEQYQALQAAIAEGALSVRYADKSVTYRSLDEMIRILKLMANDLGLSANNDGGRRFTSFSKGFYP
>NZ_CP051487|2486844:2587244|2563947_2564280_+|WP_168759160.1|holin|DBSCAN-SWA
MSHMPEKNPETWLIIMAWLSQNSPMLYAAALSCWIAFLRVIYGGGGRRQAVLESCLCGAITAGAFPLLEYFNLPSSLAAAVGAGIGTLGVKKVAALADRFTDFKLPKRQE
>NZ_CP051487|2486844:2587244|2568437_2569415_+|WP_168757776.1|DBSCAN-SWA
MRTFDSSPQAQLGFLIGQLTYVEQEVLRQPYPEIKYPSILNVDTSAPDYTESIAFKVLDYKGEPAPIGDNSHDFPLAEIAAKVGGVDVIQGGLGYKYTQIEVGKAQEMANATGFGGAINYLAEKPIAVRTLTEQWLDRVAMVGDARWPSLANGGLLKYPGVPVVATGTLLGGANKTIAAILAGGGETAANEILTLLNNAILRVYSTQTNSIFRPTHILLPLTEYGLLTTFRIPNTSETLVSYLERVLKITIEPILQAATAGAGGGNRMMVYTKNPQFAKFHLPMPYTLNAPIPAHGGLVFEAAGVVRTAGTELRVPASHLYVDGI
>NZ_CP051487|2486844:2587244|2572682_2573087_+|WP_168757783.1|DBSCAN-SWA
MALTDLSVENTIVVITTVGVIDDWGRTDPPFTVEQIDDKSTLSRGLGGNAVKFTRKNPGLRLTLNLMPGSPQAIALQAMVNAGTEASGSYASIAGLEGAVFAEGVFTRGKSMARGGPGMNDATFIAEFNKEAIV
>NZ_CP051487|2486844:2587244|2542454_2543048_-|WP_168757740.1|DBSCAN-SWA
MSQVKERPILFSAPMVRAIVEGRKTVTRRAVKFPLKDKATGRWLAGNEIGPVEVRDNSPFGQPGERLWVRETWARIGIAQAPDQEWVVYRESDNRTDYGGPWKPGIHMFRRDSRILLEITAVRVERLQDISEEQCAAEGVRAMRDDSGALVGREGPGRYVTPWPTRKEAFRDIWESVGGDWAANPWVWVVEFKKVTP
>NZ_CP051487|2486844:2587244|2537914_2538235_-|WP_168757735.1|DBSCAN-SWA
MDPYEIEDTGEWLGSPTRLETVTHYASMLEEDVQDLKRQLQAAKENISTLVEMNDQLSTELQKKLAWMANLEAETTDQLFKIRSLTLVLDQKERIICELQAGIQRS
>NZ_CP051487|2486844:2587244|2578509_2579769_+|WP_168757790.1|plate|DBSCAN-SWA
MAEITDQGITGRSLNEYLADIKTRTLAIDPNWNIDPDSPDGQRIGIDSELLTNLDEAVIAAYRSKDPDSATGEALRDIGKISGVPIRDATYSVAPITVGGPAGVGIPQGSQVRSRVDNTVWLTTAAIVIGVGMTATGFAICSTPGRVLASAGDLTIIGTPFPGWSSVTNSEAAPGDDAESDEEFRARRNRSVALAGSNMLDNMIGNIANVAGVTDVVVLQNTSVNPFDADGVPYCGIAVIVNGGSDADIGLAMYEKHNPGTPMFPRYNTKTNTWVDAPGSSGVKVDVTSPVTGNRAVMTFQRAVGLAVYVAVNVKKKGDLPSDIAAQIQQAIVADSTKGLFSGESTIGFNKNGYDIGEVVPVGRLYTPVNKVLGKYGDSYIVTLTIGLSAGAQGLTPIQPTIAQLATFDAGNIAVTVTP
>NZ_CP051487|2486844:2587244|2541943_2542357_+|WP_168757739.1|DBSCAN-SWA
MDSKEGAAIIDALAESIRSNPGQFVIQLKVVGQSFVTNGGIGAVISATGGAAGSTTIGNQVRVDGSSVDIAQGVADKAVVAQMNGLAEGLAEISRQLTSANPNKGLVAEILDSFKNSWVPTAITAVVSTVTTGLLGV
>NZ_CP051487|2486844:2587244|2558704_2558893_+|WP_168757765.1|DBSCAN-SWA
MYANPKHLHDREIKVRVDEDTFELIQALAKFHRTQRAVLCRELLEAQLAALASENTDEHQVA
>NZ_CP051487|2486844:2587244|2586596_2587244_+|WP_168759163.1|DBSCAN-SWA
MPITQQQLLQILPNAGPVAGVFVSALNGAMARFNIQGRLRVAAFLAQIGHESGQLRTLVENLNYSADALIRTWPKRFNLVTATSVARKPEKIANIVYASRLGNGPAVTGDGWRYRGRGLIQITGWVNYQACGSALSLDLLAKPELLEQPAYAALSAAWFWSSNGLNELADAGQFEAITQRINGGLNGQADRLKLWGKATAVLALQAAVTNRTPTA
>NZ_CP051487|2486844:2587244|2524566_2524935_+|WP_168757720.1|tail|DBSCAN-SWA
MAGKNRIGGIIALKLNGDMYFAKGNFTYNLGKPKKEGVVGSDRVHGYKEVPQVPFIEGEITDRNELNLEDLVTLDDATATLELANGKVIMLREAWYAGEGTGNTEEGNIALRLEGMSAEEVR
>NZ_CP051487|2486844:2587244|2496787_2497879_+|WP_168757686.1|DBSCAN-SWA
MQKLTLGQKNLIVGRNSTGKTRTLHVLASLARALSSPQSVMPPSGNYYCEWDGSGGQSYIYEYVVEGGVVKSEKLAIDGKILLDRKEGGIGEIFFEQVNNGQFLPFQTPVNEFAITMRRDTLQHSFIEPLHQWAAEVRHYYFGSSLGKEHLAIFAPNMPPVDERDPNQVVGLFKNAVRDYGDEFVNAVVSDMRSLNYNIETVEIGFPVSVIPSAVPPGINCVRVKETGVRGYVDQLTMSQGMYRVLALLININYLVVKKSSTCLIIDDIGEGLDFERACGLIGVLRKKADESDIQIIMSTNDRFVMNEVPLSEWTILHRVGSTVSVSNYINSKEKFDEFRFTGLSNFSFFEMDYLSESGEVEK
>NZ_CP051487|2486844:2587244|2522329_2522884_+|WP_168757717.1|DBSCAN-SWA
MAHPREMIRKQAVAVLLGATNVGASVYASRVRPLISNGWQSELPAIIVYTMDESGEIFNQAPREYRRRVELVVEIHAEGNDALDDTLDTLARQVERLLLMDDTLGDTANDLQYVRSRMVLLDQSEQLTGACRLIFEAEYFDRHPDDLFNQSLPDLNTVTTEYSLSNAQPNPADRAKTIIEDLNP
>NZ_CP051487|2486844:2587244|2508554_2508758_+|WP_168757701.1|DBSCAN-SWA
MINPYLAPTDPVEYRYAVHCCAYKLDLTDKPDRAVALFEHRSAAEKFGGLMWPSTFEVIDITTGEKA
>NZ_CP051487|2486844:2587244|2535075_2536128_-|WP_168757731.1|DBSCAN-SWA
MMGTLRFFMASCVVLFHLTESVPNIGMLAVVFFYAISGYLITLVLNETYKFQVKAFTENRVLRLYPAYLVTLAVGLGISLSESFKSFHHVWTITGSPLDILGNALIFPWGLVSGTTIHQFRVIPSSWSVGVELCCYAILVLFTARNIKTAMTTAALAAIWYIYITYYVTDQLLKYFPVPAAMLPFSLGAIAYFISRHSEILRQISQNQKLQASIFASCLITFTAIWYYSITTSTLIVNHWSYYANMALAFATVVVVNKARMTGLIGRIDKYLGDLAYPMFLGHFIYAFFVWRLFGGEQRGWVIFAIAYPVTILASALIVKFVDQPINKIRNRVRDSARSEVDLPAPIQTP
>NZ_CP051487|2486844:2587244|2576228_2576531_+|WP_168757786.1|DBSCAN-SWA
MSRYKVAIQALPAQTFSARLGTNTLTIELQWMARLEVFRVNILTAIGSTLTAGRFLLPGVDLLAGLYPPPEITYGSLTLEGEQPTPENLGVANLLVWSDE
>NZ_CP051487|2486844:2587244|2549250_2549448_-|WP_168757749.1|DBSCAN-SWA
MQQRKRQAWLTLPASGIEEIDHGQESIETTSEHRCNETGRRKDNTAHRQALLLWLNQHKKQDEDI
>NZ_CP051487|2486844:2587244|2503179_2503401_+|WP_168757694.1|DBSCAN-SWA
MVDDRKKQALTDWLKLLAQPEIRMDAEEQYDELLKMADAMEREGLVSEVEWRQLIRDAGVVFAQAREGLEGGT
>NZ_CP051487|2486844:2587244|2570088_2570586_+|WP_168757779.1|DBSCAN-SWA
MIRPTVSLIGKQQVEQAMKQLAKKLEGDARVLAGVPKGAGTYEDGLTLATIAAVNNFGSADGKIPARPVLGPAIEKGTPQYLRLAEVMIPKVLSGEMTMSILLEQMGQLAEGHIKQEITDLKDPPNAASTIAGKGSDNPLIDTGAFRQSIRYVIAEAGDPIEEGL
>NZ_CP051487|2486844:2587244|2551697_2552852_-|WP_168757754.1|DBSCAN-SWA
MSAKTELAVVPPQETALAVYSAEKGLEPWLQVIRSKIDGFTPDISTRKGRDAIASMAYAVARSKTALDDVGKKLVADLKEVPKKIDAERKRVRDTLDSWQEEVRRPLNEWQAAEDARVDKHNDAIERIRLLAVDLDGITAEDLADRVAQLEAVALGDVWEEFEPEAARAKDKALTVLRAALTARQKYEAEQAELARLRAEAEARAKADHEAAIAREAAEKAQREAEEKAQAERDAAAKREQALIDQAAQAQRDAERKVREAEAAAANQALQLKLAAEQAERQKLQAEADRVESIRRAEQDRIAAEQRQAAAVEQARLDEIARQNKAADEILRQEKLREADRVHKGAIYKASKEAFMQHGMTEDCARLAVMLIASGFIPAISIKY
>NZ_CP051487|2486844:2587244|2581446_2581638_+|WP_168757793.1|DBSCAN-SWA
MSQKTVYQYDASGWYMGETLADADPVVVGNWLLPARTTEVKPPLFTGGKMPKWAGYKWKLINP
>NZ_CP051487|2486844:2587244|2559724_2560483_+|WP_168759159.1|DBSCAN-SWA
MHHSIETSNPQNHVATRFMQSQNVSRTISSIELRDMVNEARSQAGEPKVRNDQFIIRVQDELGDELGECKTIAHPQSRVDMASYDLTLDQCMLVGMRESKAVRRSVLQKLKELEGPRVIATLPDFSNPAAARAWAEQFELQQAANQALIEAAPKIAFVERYVDSTGLKGFRQTAKLLKANESRFREFLIDKKIMYRMGGEWQAYQSHIDAGRFEVRAGTTDGGHAFNQSKFTPKGVTWVAGLWAQYKLQEVA
>NZ_CP051487|2486844:2587244|2560479_2561268_+|WP_168757767.1|DBSCAN-SWA
MMAALPYMQFYVADYLADTTHLTAEEHGAYMLLLFSYWQTGKPLRIDRLATVARIPNERWPSVAETLNEFFHVTETHWVQFRVEADLEAVNSKVVTASNAGKASAKARALKKQQELNDRSTIVEDPLQRNANHIDTDTDTDKNRKEHPLPPEGEDLFATFWRLYPNKVGKAAAQKAWKKLKITGDLFTLIADGLAKQVVSTAWTKDNGQFIPHPSTWLNGQRWEDEVPSPALASNVHQFAPRRQANGPDFDDKTWADDLGVL
>NZ_CP051487|2486844:2587244|2550907_2551690_-|WP_168757753.1|DBSCAN-SWA
MSNLAVTEKVERLPAIQTESATIMSIIQQVAMSPDADIDKMERLMAMHERFQAQQAKQQYDDALAQMQEEMPVIGERGGIKDKSGRIQSTYALWEDINEMIKPVMAKHGFALTFRTPRNERGIEVEGVLSHRAGHREITSIVLPVDASGSKNGVQAVASSVSYGKRYTAGLLLNITTTGEDDDGNGPAAKITPRVTSAQAAQLAMLLEKCSDKAKSAFAGIHGTPTSVEKSMFDQVLAMLTKSATQNSKTTEGKDDENHQ
>NZ_CP051487|2486844:2587244|2561267_2561927_+|WP_168757768.1|DBSCAN-SWA
MKTPNQLMQTLGNLPSVEAAPLKVDTGTADVVNSLFKELQAIFPAWRQAWPTDEALMTAKRTWVKAFMAEGIKQIEQIRFGLQNCRKLGSDFAPSVGKFIQMCQPTPEALGIPSHEAAYAESVANAHPSMAGGREWSHQAVYHAASQCGFHALNTMKAEVSRKIFDRNYDITIHMMLAGESLRNIPLALPERVDGRVTAAIGNKALADLRKNRGGHAHG
>NZ_CP051487|2486844:2587244|2564283_2564478_+|WP_168757772.1|DBSCAN-SWA
MQLIDNWKQALSMTSVQAGGAIAALGIAEQLMPQLQAVLPPVAYGVLGLLVMIARVVLQPKLSK
>NZ_CP051487|2486844:2587244|2547028_2548036_-|WP_168757746.1|DBSCAN-SWA
MPVLHSIIHKIDKKPDGSPAVLHYSGAELVESQARDELINQFNESYNAKAGKAWGLFHAESGTFPFSGWLGKYLAGNDGFVSFSDNAVEHLTKLMEESNLSVGGNALFCHYQQGLTDYLIIALVQETEAVVMTDALTLLPVRRLDLDHIHLAARINLSEWKSNPASRQYISFIKGKNGRKANDYFRDFIGCQEGVDGPGETRTLLKAFRDFVESEDLGEESAREKTHALVSYSMAHAKLGEPITIDELSELIDEDQPKMFAAFIREKDYGLSATIPADKKTLNKFRRFTGRIDGLSISFEQHLLGSKIEFDEAGGTLTLRSLPTQLTDQLKRAAA
>NZ_CP051487|2486844:2587244|2498712_2499528_-|WP_168757688.1|DBSCAN-SWA
MSLTKEAIQLIIDTALEASGKALATQTPAIVLPEGCQVVTLEKWQAGRSRFRGIYSTHSLTDFSAYVAARAIPSAKGFIDQDEMTCTLLFNLGTDALPGHADDRAILKLKPSAGYKAAQGIGGRVMTQKDLSDWIEDWHQYLTPVDDEGKEIPVARAIAAVRTITIKATNESETTVGDTSASRSAMDQIEARSKETLPAALLFSTIPYEGLTEQRINLRISVITSSSQPALKLRWVGEEVQREDIAQEFKTVLQKKIGNAAALSLGAFDPK
>NZ_CP051487|2486844:2587244|2511417_2511771_+|WP_168757706.1|DBSCAN-SWA
MARTKSFTERTSEDLLEHWGRWVVLGSGVSCCASRENTLHTPMITDDDALMIDGLMGRLLKRYPECGNVLMKYYTARDKALVDVGKKLGFGEEKTRQLWKAGIAWIDGALDFRRAAA
>NZ_CP051487|2486844:2587244|2512631_2512976_+|WP_168757709.1|DBSCAN-SWA
MNYELISSIACGVIALWATWCVLSGRVRDGILGKLIYSAIAISGFVVMTRNQNIFIGPTTAGLTLHVSLALAGIRHVFMVIWWQRVKAWLCRTLNCEHCLGCNKGHAPDDRHKS
>NZ_CP051487|2486844:2587244|2490067_2491084_+|WP_020799067.1|tRNA|DBSCAN-SWA
MENLDALVSQALEAVQSAEDINALEQIRVHYLGKKGELTQVMKTLGNLPAEERPQVGALINVAKERVTEVLNARKALFEEADMAAKLSAESIDVTLPGRGQASGGLHPVTRTLERIEQFFTHIGYGIAEGPEVEDDYHNFEALNIPGHHPARSMHDTFYFNANMLLRTHTSPVQVRTMESKQPPIRIVCPGRVYRSDSDITHSPMFHQVEGLLVDRDINFADLKGTIEEFLRVFFEKELAVRFRPSYFPFTEPSAEVDMECVMCSGKGCRVCKQTGWLEVMGCGMVHPNVLRMSGIDPEEFSGFAFGMGVERLAMLRYGVNDLRLFFDNDLRFLAQFR
>NZ_CP051487|2486844:2587244|2578144_2578510_+|WP_168757789.1|DBSCAN-SWA
MTVRKLDTDGDLAMGPQEFLTGYSAEEVAQNVLTRLKFFLGEWFLDTADGTDWFGSVLGKGSALASRESVIRRRILLTPGCAGMTAFSMTTDIATRQLTVSASIVSSSGDSAEINYVQAVI
>NZ_CP051487|2486844:2587244|2496036_2496249_-|WP_104449552.1|DBSCAN-SWA
MKKELIKISEFQRRRWGENGTPQCPQAIRNHIRNGIVPGEQIGKLWYVDWAAFSRSNGNDLVAMVLKGAA
>NZ_CP051487|2486844:2587244|2507129_2507882_+|WP_168757700.1|DBSCAN-SWA
MAGDWIKFELTTLDKPEVCQIADLADIDPDAVVGKLMRVWGWFDQQTENGNAPSVSKKLLDRLVGVIGFCEHMKSVAWMIEAEGVISLPHFERHNGKTAKNRLLTAKRVANHKASNGKSNAANVSGALPKEDLEKNKEPLSAQEAVDPRMPSEMTLDWVPDQTLLKTYALHRGLSLDLFTEQVRVAFTGHYEPQHQVNTQAEWVGMLVKWVNNDKARAAAASNVKQFKPKQAPASDFDDDDTEWQNGVNS
>NZ_CP051487|2486844:2587244|2493495_2493798_+|WP_002553164.1|DBSCAN-SWA
MGALTKAEMAERLYEELGLNKREAKELVELFFEEIRHALEDNEQVKLSGFGNFDLRDKRQRPGRNPKTGEEIPITARRVVTFRPGQKLKARVEAYAGTKS
>NZ_CP051487|2486844:2587244|2486844_2488767_+|WP_008066670.1|tRNA|DBSCAN-SWA
MPTITLPDGSQRSFDHPVSVAEVAASIGAGLAKATVAGKVDGKLVDASDIISSDATLQIITPKDEEGLEIIRHSCAHLVGHAVKQLYPTAKMVIGPVIDEGFYYDIAFERPFTPDDLAAIEQRMQQLIEKDYDVIKKVTPRAEVIEVFKARGEDYKLRLVEDMPNEQAMGLYYHEEYVDMCRGPHVPNTRFLKSFKLTKLSGAYWRGDAKNEQLQRVYGTAWADKKQLAAYIQRIEEAEKRDHRKIGKRLGLFHTQEESPGMVFWHPNGWTLYQVLEQYMRKVQRDNGYLEIKTPQVVDRSLWEKSGHWANYADNMFTTQSENRDYAIKPMNCPCHVQVFNQGLKSYRELPMRLAEFGACHRNEPSGALHGIMRVRAFTQDDAHIFCTEEQMQAESAAFIKLTMDVYADFGFKDVEMKLSTRPEKRVGSDELWDRAEAALAAALDSAGLPYDLQPGEGAFYGPKIEFSLKDCLGRVWQCGTLQLDFNLPVRLGAEFVSEDNSRKHPVMLHRAILGSFERFVGILIEHYEGAFPAWLAPTQAVIMNITDKQADFAAEVEKTLNESGFRAKSDLRNEKIGFKIREHTLLKVPYLLVIGDREVEMQTVAVRTREGADLGSMPVAQFAEFLAQAVSRRGRQDSE
>NZ_CP051487|2486844:2587244|2549465_2549822_-|WP_168757750.1|DBSCAN-SWA
MDQAIEEAAKRQCGLEAAKAAFFASGGQAQLIPTGLGKDSPGVDQIPKPAYGYRNIEAPKSKRGRLISDDEKAALAAQLVECKAAGMTRYKASKHLGISETLCRRLIADYSLDFPASA
>NZ_CP051487|2486844:2587244|2511867_2512101_-|WP_168757707.1|DBSCAN-SWA
MKQRQQQTDAFKVKTESGKVYGIAEFTHQIYQEFLNPADNGWANGMKQYKVAGGGNANKKSETEYEIVATGELAVRI
>NZ_CP051487|2486844:2587244|2555090_2555468_-|WP_168757759.1|DBSCAN-SWA
MDAPDKNCPFCAEPIKAEAIRCKHCQVSLLTGTADGAPPPKSKKPIWPWIILTPLLILGTLMVVGAMSGPPDEKTKARSAIDLCWKGVDDELQSLSTRRFVRGTCQMMVEKYETKYGRSPTLRRE
>NZ_CP051487|2486844:2587244|2569657_2570092_+|WP_168757778.1|DBSCAN-SWA
MAELTIDVTPAIIADFRAFYEEFSDSAAWSDSKITKALYIARGELDACRWGDYKPYSLLQRGWFALAAHYLTWNTATTDATTAGGSASTPYAVASKGVRDESVSYAIPAANANLTTWEAALALTPYGVEYLHLRGRAGMGAVCV
>NZ_CP051487|2486844:2587244|2514368_2516306_+|WP_168757712.1|terminase|DBSCAN-SWA
MSTLSPWLNDLRKSIKLGLQALYKEPPQTAVEWADANFYMSAESSYNEGKWTTEPFQVAILNSMGNDLINVVNFIKSARIGYTKLLMANIGYKIQHKRRNVMMWSPTDPDAEDISKSHVNGMIRDVPVLGDLAPWFGRKHSDNTLDQKIFANRRTLWIRGGKASRNYREKSADEVIYDELSNFDESVEGEGAPITLGDKRLNGAIYPKSIRGSTPKRVGSCQITKAVEESPYLLKFHIDCPHCRQEQTLKWGGKDCEFGLKWEKNALGEAEKAWYVCEHAACIIWHNEMVEASKTGRWICEHTGIWTRDGMDWFGADDEIIRTPRSVSFSIWAIYSTWSTWLSLAEEWLKIKGDVSKLITFINTTRGETWDDDQGEKLDSEVLYGRREVFPQVPALGLVLVGGIDTQDDRFEGRVWAFGPGEEAWLVHRFILMGDPASEELRRKVGLELHRQFTRVDGTIMKVERWTWDAGGHYADEVYAESRKHGVHWVVPIRGATVYGKPIANFPRTKNKVHKVYLTEVGTDNAKELLYSRMGLPVDTAASQAGMSQPGVVHLPANDAICDESEVKQLTSEKKKAAISKGKRVMRWDSGGRRNEALDCFVYALAALRICQQRFGLDLDLLVAAVTGGNEPDAEERPRKKSTFW
>NZ_CP051487|2486844:2587244|2539731_2539875_-|WP_168756983.1|DBSCAN-SWA
MPNSDLLPSLLFKINENQFVLEAAILEFSNWGEHHGAAEVANNVRGF
>NZ_CP051487|2486844:2587244|2557340_2557529_-|WP_168757762.1|DBSCAN-SWA
MAHSLQYQIGDSIRIIEAEVARLLDVVDALKEAGSDELSESVLSQAHKILEAAIALRIVGAG
>NZ_CP051487|2486844:2587244|2543044_2543359_-|WP_168757741.1|DBSCAN-SWA
MPAEKLIGPVEVTRDADGYWYHPDIPEFDEDAEAWKAWLETQGLKVIGWHMESDLEAHPYWDDEACHCLGWELEPPPDDGWFLLGIFDTDNGPYVQWARREVTP
>NZ_CP051487|2486844:2587244|2489378_2489573_+|WP_002553160.1|DBSCAN-SWA
MPKMKTKSGAAKRFLKTANGIKHKHAFKSHILTKMSTKRKRQLRGSSLLHPSDVAKVERMLRLR
>NZ_CP051487|2486844:2587244|2557555_2558371_-|WP_168757763.1|DBSCAN-SWA
MTKDSRRLPLAEWQLEDSDRLKEIFQRKRGALKLTQEKLAAELGDGVTQGAVSHFMNRRTALSLKAAAVFARMLEVPVSDFSPTLAEQLGKLSSSLTPSHEQGMARELVGGVAANTPFPAGDDVNHSLDDRYAFIPQYDAKAAAGIGHENPHVEVRSTLAFKREWLKVKGVNPNQLVVIYADGESMWPTINDRDVLLIDRSKIDPIDRQVFVLASADKGAIVKRLIKTTLGGWIIRSDNENKDEHPDLILSRKEINEHRIIGQVIWRGGDL
>NZ_CP051487|2486844:2587244|2555652_2556174_-|WP_168757760.1|DBSCAN-SWA
MALPTPTDLQRMALPKKFTALLSVLGLHRPAHVDSKEWHQLCQLYKVMWEAKQGDGFEALAKRLIAHISYYQKTIEAEGEAFVSIAISRKKRRKANRCGLFIGNASFSDSSQEAARKRNSTPKIGLGVKSILAPPQRTRREELKIDSHTQLPEKSPSSHILYVAGWTLSSEQE
>NZ_CP051487|2486844:2587244|2503808_2503988_-|WP_168757695.1|DBSCAN-SWA
MTNAMTFFALTLLAGCSAHEPAPPLLPEGNMPMTEQEYEEAELLLIKKQELPPDKNAKY
>NZ_CP051487|2486844:2587244|2548115_2548364_-|WP_168757747.1|DBSCAN-SWA
MAKSPTERKRDQRERDKLTEQERLARLLSRKIVTLLYHNDDAALIRTMARTGIDEEQDLISRFIHAADRMTDEELGAHISIS
>NZ_CP051487|2486844:2587244|2550306_2550924_-|WP_168757752.1|DBSCAN-SWA
MKIISNVEQGTQEWLDLRLGIVTCSELDTLLVNGKGEAGFGAGAFTYMNTLIGERITGEAADPFQGNRHTERGHEYEGIARGLYQSQLDVTTEQVGIILNHGIGYSPDSLIGEDGLCEIKTKLPKFQVEVILSGEIPKEHVAQCQGGLWVSDREWIDFVSYWPGMKLFVKRAYRDEVMIRKMNERVKTFYEILDERMNRVLGIAA
>NZ_CP051487|2486844:2587244|2534631_2535033_+|WP_168757730.1|tail|DBSCAN-SWA
MDRYALIELSTELVVNVAIWDGETEWAPEEGVIAIQSDSAQIGHSYVKGEFIAPPAPEDPPLTPEEILAVNEKTKVNLMAQASQAMTPLLVSLQLGNATDAETTSAQAWQAYCRALNLADLTIESPAWPVVPT
>NZ_CP051487|2486844:2587244|2530394_2530862_+|WP_168757726.1|DBSCAN-SWA
MADAAMVMTENGGELLLSGFDLARDDGLETAVIISLFTDRRASAEQLPVELPQDDLRGYWGDIGNATPSDQTGSLLWLLAREKQLPQILGRAQQYCREALAWMVEDLVATRVEVKAEFVAQGWMLILVDIFRPTGSPVRYRFNYEWAAQAAKRPA
>NZ_CP051487|2486844:2587244|2577473_2578148_+|WP_168757788.1|DBSCAN-SWA
MTDPLASRTQAEFTKMLRGVFGEYLKDNMHTSVPGHVLSFNPVTQLAEVQIGLMIEDHQDNQAARRPIICVPVQFWGAAGGTLECRVANGTEGALFFSKECIDSWVDQGGVAIKSEPRRFSINDCYFIPGIRSIPGAITNFANDGIRLRSNDGSAYIWIHDNKTLEFDGVSANFKCPVNFEQPTNFEQAVTTETTIHNQGVSIGLEHEHIGVEVGDDISGPVNP
>NZ_CP051487|2486844:2587244|2582092_2583703_+|WP_168757795.1|terminase|DBSCAN-SWA
MSALLDWDSMSREEKEASKLISEHSPLAFMRVFFQINQGMKFLCNWHHRYMDYTAKQVLAGELKNVVFNMPPGGTKTEYWSIHLPAYVMTKFDRTRNLSVSYSKSLVEENSNRIKSIITSSEYQELWPCELGKADVANWIITDENGRNKHQIFSRSTGGQITGVRGGYISEGFTGFINLDDPEKADSAFSATMRAKAQRIVTNTLRSRRASPDTPVICTQQRLHTDDVSGFLLKGGMGLDFSHIKVPALVTRDYIEGLPAEIREHAERDVFSGPSIVRGGVEYWSYWPAKETVADLMALWDRDPYTMVSQYQQEPVALSGGMIDADWFKTYQQLPYLVWRGVYVDTAQKTGEQHDYSVFSHCGLGVDGNLYIIEVYRGKWDAGDLETEALRVWQKWKDWDQFRPAALRYMRVEDKSSGTGLIQTISKKGGIPIEAQPRGPAANKVTRCMDAVPWLKSGRVFVPAIYDDQGCKIEHVRDHRGEIVASTDWVAPFLTEASAFTADDTHAHDDQVDTIFDAVADMLISNGGEFFSSNWL
>NZ_CP051487|2486844:2587244|2511093_2511414_+|WP_168757705.1|DBSCAN-SWA
MKKNHGPAFRAAQLDLARCPVCKGRAVVKGVFHDLACVQCNASGWIAAETGESLPLEILVTQLSIRLQAADQQIEQLKSGSLMAGPAAQYEHNNRRGAGGSNYTGD
>NZ_CP051487|2486844:2587244|2544335_2546405_-|WP_168757743.1|DBSCAN-SWA
MSAQQKKHPFDFKTQYGLGFSSQDDEIVVDFFCGGGGAGTGLEMGLGRAVNVAKNHSPQAISMHTVNHPGAVHYTTDVFEGNPDTECDGKAVGWFHMSPDCTHHSQAAGGQPRKREIRNLSWIGLKWAGKKKPRVISLENVKQILQWGPLIAKRDKSTGRVVKLGGGVAEQGEVVPVHQQFLVPDPKRRGQTWTVFVAELQHLGYVVEWRVIKACDFGAPTSRERLFMIARCDGQPIVWPAPTHAKHPVKGQQKWRTAAECIDWTIPSKSIFDRPKPLAPATLRRIAKGMKKFVIDAADPFIVPIANWSGDSVQSAHDPLRTVTSWPRGGSFAMASPIIAPATHQGSDRINDPHAPLPTVTCANRGELTLISPVMVTAAHGEGKPGGVQRWGDGSKFAGDPLGTVTASGGHSIAAAHLVKFRFTDEGKALDEPLPTITSGGNYQRPAGAAHAMGISTVFMAQMNGGFNTTAAKSIEDPMTTVTNTGSQQQLVTANLVHLRGNCDARDAADPLHTISAGGTHHGLVTAFMERQFGASVGKAVNEPAPTITAGGGGKSSLVELQLSPEVEAGALRVAAFLISYYGTENMSAADAPAPTITTKDRLGLVTVTIKGTPYVIVDICLRMLQPAELYKAQGFPADYIISHGADGKPFTKTQQVHMCGNSVSPPPMAALARANDPWRVSDRQAEAA
>NZ_CP051487|2486844:2587244|2569424_2569607_+|WP_168757777.1|DBSCAN-SWA
MATLTNASVHPLVLADLTIQPGEVIEDFDDKAAEELKDSLFVKAKWLKIEQAPKPDSKAK
>NZ_CP051487|2486844:2587244|2523068_2524541_+|WP_168757719.1|tail|DBSCAN-SWA
MSIGFNTIPGPGALHKPGVYSEIDNSQAVSGPQAVTYRRLLIGQKLVAGLAPAGALIRITSAAQADTQFGAGSMLAGMVRAALAVDSYTELQVMPLVDNAAGVAATGTLVFTGTATASGTIELMIAGRRVSVGVISGNTAAIIATAVAAAITAAADMPVTAAAATGTVTLTCRHKGEAGNSINARVNYYSGQALPAGVTLVITGLAGGTSNPSLATALAAIGDEWFHAWGVAYSDAATLAELKVELDSRFAWGREIEAHAFTAARGTQGTLSALGRSHNNEHLVIAMANDEPMPAYEKAAETMAIAAYYAAIDPARPIQNLPYVWCLPPAAANRLTNQERNLLLFDGIATTKVSSDGVMLAERLITTYKTNAAGASDISYLDSETLFTLMYIRHDWRDYILRKYPRHKLADDGTRYGIGQAVVTPVVMKAEAIAKFREWEDLGLVENIDDFKANLIAERNASDPNRMDVLLPPDLVNQLRIVANKIQFRL
>NZ_CP051487|2486844:2587244|2520788_2522057_-|WP_042955929.1|transposase|DBSCAN-SWA
MQTLLSQRFTAYVGIDWADTKHDVCLQVAGESRRHFSVIDHTPQSIDRWAKSLFERYGAPIAIALELNKGPLVAALQKYEFFCLFPINPSTLAKHRKAFVGSGAKDDPTDAQWALELLLTYPQRFAQLMPQSPAMRILASLTEHRRALVDERVKVSNRLICTLKQYYPAALELFSNHDSVVFCDFLMRWPTLEHLKRSRQSTFLKFFNEHNARHAQLNQTRWEIITQAMPLTQDPGVIRPSQLYATALASQLKGLICTLKDFDREIQETANSLADYPIFKALPGAGQHLAPRLMVAFGEQRDRFSDANAMQRYAGIAPVTQRSGKKTVVYWRYQCSTFLRQTFVEWAAHSITQSTWAEAYYRQQRAKGCSYQATLRALAFKWIRIVYRCWKTSTYYDEKAYLQALTGRGSTLVEAPMEVVSG
>NZ_CP051487|2486844:2587244|2562023_2562494_+|WP_168757769.1|DBSCAN-SWA
MTDKISVNSQAKLSEAITSLTTMYRDKKFVVVSLRPGKDRTLDQNALWFSLYQRIAAMTQIGDVDDARRYCKLHFGVQILLNEEDDFRAAWYQTMRHLSYAQKLDMMGGCSLFGPDGFPVTRLFSRAQGIAYTDRIVADFTERGVVFTDLLGEVAA
>NZ_CP051487|2486844:2587244|2556324_2557191_-|WP_168757761.1|DBSCAN-SWA
MGKIEGYQLDLAIPMNEQDVFHFDDSRPHFDGLCRKNGITYWYARDFMKMVGYQTFSSFQKAVQKAIASCTTLGIDIMENFQQVDREIDGKIERDYKLSRFACYLTAMNGDGKKPEVARAQAYFAAVAETFKRYIDQAEDVERVLIRDEISLHEKSLSGVAKQAGVTEYHFFQNAGYRGLYNMNMSDLKNRKGLIGKESSRSLLDFMGKQELAANLFRVTQTEAKMENEGIRGQKAAERAAEAVGRKVRETMIEISGDAPESLPLARDLKQVKSDLKASSKEFKKLDK
>NZ_CP051487|2486844:2587244|2554197_2554656_-|WP_168757758.1|DBSCAN-SWA
MKIVEIIEHVELYWSNDRWNLSLSGSAEGFARIARGLIYDRTGSFYIAQNEGLINFCSAGSDGACGGSFTMRDGSIENVVGAWSSNSDSVFKATGIDSVSASFNNQVIALSIPALKAIGVRFGFVINEVTDAYRHHITPIPPATRMTLVDRS
>NZ_CP051487|2486844:2587244|2500303_2500585_-|WP_168757691.1|DBSCAN-SWA
MQSLMQQSFAGLQALRLRSVIATSEFYSMIGRELPVQKIRYQVVTKGKAYHIIELATRKVKGFRWTWKEAVNFAQQLEARADSIKVSLSEDRK
>NZ_CP051487|2486844:2587244|2559162_2559369_+|WP_168757766.1|DBSCAN-SWA
MAYDDKAHRHDHQVKVRLDDEDFHELKGYAHELKAQHSVLAREIILAALAFKKEHGYLPLISEKKLRA
>NZ_CP051487|2486844:2587244|2530861_2531920_+|WP_168757727.1|plate|DBSCAN-SWA
MPFARPTLTELIDRVITDISSRVTGVDSAVLRRSLLGVIGQSEAGAVHMLYGHLDWIAKQSVIDTADTEYLERWAAIWKVVRKTAGFASGSVAFSGTAGSTILDGTIVQRQDGVQYKVLGDAVFGSGPLVVPVLALEAGEAGNFGSGLPIFLLSPIAGIQSTGTTATKIENGVDTESDQRLLARLLARIQQPPHGGADFDYQMWALEVAGVTRVWVYPRQMGAGTVTVLFVCDDLPDIIATPAKVAEVQAYINARAPVTAEVFVAAPIADSLNLTIKLTPNTTTVQNAVRAELTDLIDRDSAPGGTILISRLREAVSLAAGENNNQIVTPTADVAHATGHMPILGTLTFSSF
>NZ_CP051487|2486844:2587244|2528758_2529883_+|WP_168757724.1|DBSCAN-SWA
MDDLELLVNGMKYAGWTSLGVTRAIDAATTAFTASLTEKWEAGNRSLAQVEPWPILPGDACEVRLAGFPMVIGYVDIFKPSYSANDHTINVQGRDKVADLVDCSAVHAPDEWKNIDLLKFAQILAAPFGVTVKADIAVGEPFQVCKLQQGETAFKAIERYARQRKALLMPDGAGGLLITRAGVRRATTALVQGENILNASGTIDHSQRFSNYQVKGQASYSPDSTGETEAHIEGSVTDSGIKRYRPMLLVAEIGGTTASLQDRATWEANSRIGKSAAASVSVYGWRQSPGGALWEPGMLVYVRSSWLRMDGWMLIRQVTYERGEGGTTAKLEIVSPQAFDPEPPDGKKAKKTKAGKKGQRNIWAEAIGEEDPPK
>NZ_CP051487|2486844:2587244|2562490_2563081_+|WP_168757770.1|DBSCAN-SWA
MRAAIKEKKAPNLKKCRVESCRASFVPARLGQAVCSPTCAILDAPKNLEKARKALDQFERKEIKVRKERLKSRADYLKDTQIAFNAWVRARDAQLPCVSCGRHHQGKYDAGHYRTVGSNPALRFEPLNCHRQCSPCNTRLSGNIVNYRIELVKRIGAESVEWLEGPHEAKKYTIEELKAMTAEYRAKTRELKGRAA
>NZ_CP051487|2486844:2587244|2510581_2511094_+|WP_168757704.1|DBSCAN-SWA
MMIQGDFPDLAELQRLAELVPALDERRCLVDPEEHGRRFVEEVVRLFDTDYGMAKAFISEVERLQAENEALRKAVNFSVEMFGKITSGDGSGHADLSRAVLRIAGAALAGDDVFRKDAERYRWLQRRLIGVLKDWDDRGKGMLGLSFMIPGDAWRTCDENIDAAMAGGGR
>NZ_CP051487|2486844:2587244|2546488_2546722_+|WP_168757744.1|DBSCAN-SWA
MSDEFYKRLLGIPKQNQLFSGNSIFGITTGEDILNFSELDAAGSTVAHYRVVEQRIGYLGEGGSITWHRTEVKSKQD
>NZ_CP051487|2486844:2587244|2583770_2586458_+|WP_168757796.1|DBSCAN-SWA
MADQTQRLDIATVKAEIGSDILSRFSNDAVTADPISTDSGTIPNLKQVIVSIQEGGAEKISFASTIYSTTAAGIAATTNGAIFLVKSDEADEIYAVWQNSSGVATDTGKRAMAAQAIQDAMQSATEAAQAAEDSADLATGRTARFLVSVATPPVIRDDGTPLQLGDRYVNTENQAEYIYKSSGWIVNESLEAIAAIKDDTDPANGAAQVGWDGETVGAQMSLSKKIADYAALRVYTGTATGFKITDANFSGNFILDPSDTVSADDKSTVIVGAAGRRYKRIYDGRIQAAWCEGASDSAIIQASIDAALREGKSEVGIDRDYICDTALTNRTNIRFVGAGSLSGDSCYRVRVMPEWAPTGREPFQDLIPAQHLRAFSAAPAPTVVIVGSSTGGWAADSIDTGGGVTPMLQRLLGKYNPEKNISFYNRCIGSQTFAALNSKPTSFPSWYTDTGRDWLQYIADLAPDTVYIICGSNDSSSAERPVIKSILDKLAAFAKSPDVVFFTQPSVCPDPDPAFASSGTRASQEGRDYAAGLVRSMARYYKKGLIDANRMGGIVLDGRDILDNASMRILPSIPVTSGRFAPGLSTIDFSMSLNFNGSAAANDAAFLVGATNPVFVKTGAVGANSDSGDIAYIQKTAEGFLRVQLYSDGLYQTLTTGVVFPTTSFTLDVIKVGNVLTLSFNGSEDIARVSFNIIAAGGEMYPRTGYYNLTSGPWTSVVLNVGLPKLYKKLLTSQEAWGLPNPAASRQMPYGGNGLNHLSSLGTREIYGRVMDTPALRGVNTDFGEYSPGLTPGTGTPTVTAPVTWAWTRNGNIVHVDGVVSVSLASGSTCSFSATLPIVPAVLNQDKTIALIMSTGAGQTGAGFGDPANKVVQITLQGASPTAAKYRVMLSYRLS
>NZ_CP051487|2486844:2587244|2563077_2563659_+|WP_168757771.1|DBSCAN-SWA
MKINSARQAWHDCTYNPAPGQTSDAAELGVVVQGAERGPTANHAVHGALAGQIQSAIARLHRQLRAFGNAMYAAEPTDDDREEAEEAVFNLACSRAPRMTADKRERAEYVAKGVFRRYRYMHQGGQSANDDPLIKPELFRTWMNAEYGIKLPSAAWGRDWEPFVQLCFDACYDIDAKALSPIGGVIYKMKEAA
>NZ_CP051487|2486844:2587244|2575611_2576232_+|WP_168757785.1|DBSCAN-SWA
MSLMSIFTKTLPKIGPLEFDAKLEGVTSKSVYLTQFPVEFGANMNDHAILLPNRYLLTGAVSNTPLGLDLSDIGMMGVGAVATAVGGIGGAAISAVSAYLLSGSEETRASTAWASLTAILEARAKFDLDTGKEIMRDMMLIRLDERTRPENEDGLVFIAELQQARIVRSKVGQGVTSADQLMKNDTVTTQGAPMVTTGEASVEVIR
>NZ_CP051487|2486844:2587244|2570585_2571005_+|WP_168757780.1|DBSCAN-SWA
MGLNMRGHVSGPFVTHKGVVLNRYTSEVVDFEPVLALTYNDTFNANVQPVSDKEIEFLQIGAERINDVRVIHRNDGKGIEVSTPGKLADILVFAETPDKPVTWWKSIATDFRPWHNFCRAVVAKLDPAEIATLEAHTDA
>NZ_CP051487|2486844:2587244|2504525_2505407_-|WP_168757697.1|DBSCAN-SWA
MTKKRILPPDRMAECEAAHALFLSKKNELKLSQKKIADAAGMTPAAVNLYFKGINPLNAQFAAVLARLIQEPVEAFSPRLAEEIRNLTGAPVTKAPSVGDTSGATAADAIRDMLSRSGKNLSEDARRRLIAVAEAEEGGGAIEIDYYRPGVMGDEVWIAHYDVRAAMGGGQIPHDYPEMLQDVRVSPQHLREMGVDFKEHFHLKMVTGWGQSMAPTIKHRDPLLVDISIREFTGDGIYMFSWEGHLYIKRLQWLGDEQINMLSDNPRHPPQTIKAEDTYIQARVLLVWNANLV
>NZ_CP051487|2486844:2587244|2538315_2538525_-|WP_168757736.1|DBSCAN-SWA
MSNSDLLPSLLFKINENQLALEAAILELSKWVEQRGAADVADNVRGALDTIDKNEEFIKLTLAVLMTPD
>NZ_CP051487|2486844:2587244|2576523_2577477_+|WP_168757787.1|DBSCAN-SWA
MSDELFLRSYRLKVGRVTGSRVYEMRTGEIVPGDNDGLRITFQATHFAGNALSVAEITIYNVSAYAERQMLGDGVTKKYEFISLEAGYAGQFGAVFVGQIVNVQRHLEDGGATKGIRFFCKSSAKERDQNLINLTLSPETDPVQIIEACAEPFGAEIQFYGDFSELKRRSRGTVLQGSPTACMNELAEAFQFDWMVENGALKVIKREFALANQVYVISAGTGMIGSPVVTDTEVGIRYALNPKIKLGDTIKLESMAPRFEFSGAFFYDIPRTIGEGFYKVNSLVFAGDSHGDQWEAQLSCLRLSAAAQAGISQRATR
>NZ_CP051487|2486844:2587244|2529879_2530395_+|WP_168757725.1|plate|DBSCAN-SWA
MREALREIGSRVMMMFSRGVLRGVNDSGPRQQVQVELLKDELRDGLEHMQNYGFTSHPKGGDVAVAFLGGNREQGIVLVVDDRRYRIPLLAGEVAIYDDLGNKIELLREMVKVTAVQHLEAVAPTIKLVGDLEVIGNITSTGTIKNNGKDIGSTHKHNGVTAGSGTSGVPI
>NZ_CP051487|2486844:2587244|2524934_2525237_+|WP_168757721.1|DBSCAN-SWA
MAKEKVIQLVEPAEFGKQSFTEVTVTRKLKYLRGHALRITSDGKGSGGVDMDFATLIDLAAKMVGQPTAMIEELSEDDQAVLIQEARDFLLKHLGGGSQE
>NZ_CP051487|2486844:2587244|2579765_2580425_+|WP_168757791.1|DBSCAN-SWA
MIMDHVARARSRIINEYRDKPRMERWLTITPEIANKHLESPLSQIYASYDVDTVTGERLDIIGRIVGMPRPILRGAAYDVFGYAGNDTYTNYNISPYIGDGAMVDAPLNNDLYRKLIKAKIARNISDGTADSIIQLVEMIIDVKVTALIDNGDKSFDIGIASELDNTTEYLLNNFDIIPCPQGARLNSIFVLPTNISEIEQTSLRVYTFANVTLPGDLA
>NZ_CP051487|2486844:2587244|2536731_2537265_+|WP_168757733.1|DBSCAN-SWA
MRAMLRILPYIAAVLLVAAVLFGVYHHGVTVTDEKWQSEWNSRDTHDAAARALNEAAERTKEQAYQQSINKAVQDGQRIIDQATADAAAARTSADSLRGAADALANRLAASEASGDSCTAAAGQATAHFAMVLADVFKRADERAGELAAIADQARARGAACEMAYDGVANGSISAGP
>NZ_CP051487|2486844:2587244|2531928_2533737_+|WP_168757728.1|DBSCAN-SWA
MSTAAEYREQLKALLPPGQAFPRDPGTTLHDLLDGMSLELARVDDRASALPQEVNPNTTLELLPDWERVAGLPDKCSGTLEETLQGRRNALLAKLTSTGGQSADYFIQLAASLGYAVTIEVFRPFRAGSSVAGDVLSNGDWVFAWRIHAPDVTVIPFRAGLSVTGERLRVWGSDTLECKIRQLAPAHTIPIFAYGDATLDLNFVQDTYRSGANNTTFAGLITFTRSTTAGRFNAAGLFEMVPINQPRFDYDPLTLAPKGLLMEEARTNLLRFSAQFDNAAWIKFETTVSANATAAPDGTLTADKMVESTNTTSHTADQQINGTYTAGQVFCASCFLKAGERSSIRMNLYYAVGSTGGRQIVFNLATKSITSKDPAIPTAGVEDVGNGWLRCWFTGVVDTPAETRLLMRVQLAIGTTTTYAGDGTSGAYFWGADIQESASLLSHIPTTTVPVTRSADVAAVNTLTPWFSPARGTLYSEATNVGPSGTTIAQLGSLSDRILTSVAPSGIAGTGGATIVGSVNQASMQSAVGAPGQKVAFAYSTDDFACATNGVLIGTDTSGSLPSVSSLLLGRNGASTTNCHIRQITYSPKRLSNERLQAMTAP
>NZ_CP051487|2486844:2587244|2567917_2568427_+|WP_168757775.1|DBSCAN-SWA
MGVAIDTFGQYAGKAYEGQINDLSMADVTSAVASVAIPFGRAVVSDTADRSGKLPAAGAGFFLGISVRKPVGVSGSYLTGQVSDSGNAVGGYRAGEEVSLLSHGRIWVKTLAGAVKGAKVYALPTTGEITNAATAGNHELVGCTFLTAAAAGELVLVQVKAVATTTLAA
>NZ_CP051487|2486844:2587244|2518048_2520004_+|WP_168757715.1|DBSCAN-SWA
MLSLRAAVRAGSVDVDARTVELTWTTGAKGRRWSWDVGSYMEELEVSEDAVRLDRLNNGAPFLNAHNSYELDAVIGVVEKAWIEGAEGRALIRFSQRDDVEKIFKDVQDGILRNISVGYAVHRYEVTESADDKLPTYRAVDWEPMEISLVPIGFDDGGKFRSAKTAADYQGQRFNTIFEVREAPQPPDQPAAVANTTEENPMTEEEKRAAEEQIRRQAEEAERKRSLTIRQMAKKVGLGDDVADDLVARGVSIADASAALIDKVAERQAGSQTETRNSQPTVVGGLDQTVLTAKREAMQNALLNRCNPTIALIDGAREFRGMRLLDLARECVETVGGNARGMLPQEVARAALGCDRTAMRAAGMQTTSDFPILLGGGVTRTLRDAYAQAPQTWRLLGQQTTVPDFRATTRAALGDIAALEEVKEHGEYKYGKLEEEGAPIRVTKFGKIIAITWEAVINDDLGALTRIPRAYGLAAAETESNLVWNLILSNPNFTDNNPIYVAAHGNLAASGGAINTTTLGAARAAMRKQKSKAGAFLNVEPRYLVVGPDKELEAFQFTSSQYVPAKNSDINDGRNTSLVVIVDGRITGNQWYLFTEAGLIDTFEYAYLEGEPGVFTETREGFEVDGMEIKARLVFGAAWIDWRGTYKNPGA
>NZ_CP051487|2486844:2587244|2580424_2581450_+|WP_168757792.1|tail|DBSCAN-SWA
MARQPFNTRWAQGVETEDSLNSFKAPGDVRLSTGWEGGQDKDAPPAGQENWWHNRVDSALQDLERRGVMTWHPQAIYDKGAPCYADDGYYYESLSDLNSGHNPLSSSAFWRQLGQSLYSSFSVGEYKDVAHNGTPDSGWLKSNGALLFRTAYPKLFSKIGTTYNVGGELSTQFRLPDWRGAFPRCLDDGRGIDGGRGLNNTLQPSQNLSHAHSASSSNVGDHAHSASSAGAGGHAHSASSAGAGGHTHDTAISRERITAAFVPSGGNAVFGDQESDGTNTFTSSSAGNHAHGITVDGVGDHAHGIAVQPAGSHSHTISIGSNGGAEARSTNLAQVRWIRYL
>NZ_CP051487|2486844:2587244|2570997_2571555_+|WP_168757781.1|DBSCAN-SWA
MLDEKALSKAVCRIVVAATGLPANKVILADNNTAAPAGSYCAVRLQNPEQFGQALNSQRNVPAEDDPQYTDIIAKVATQFTLGFSINFYRSGAMGYAAAICEANKREPIKALLRTAKLGWSRVSPINNLTGLYQAAMEERAQLTLYLYGESIAEDRVQRIYRVGFSAQTEQSGATAQGEVNGLSG
>NZ_CP051487|2486844:2587244|2581646_2582096_+|WP_168757794.1|terminase|DBSCAN-SWA
MERPRKRRFTDKMEAFCLVYMETNNASEAYRRSYNVTNMADKTAARESWIVLQKPQVQARIAELREAVMDRHQITVDTLLAELEEARTAALAAETPQTSAAVSATMGKAKLLGLDKKIVEITGKNGGAIETKSRVTVDKKTLESVLDRL
>NZ_CP051487|2486844:2587244|2498013_2498580_+|WP_168757687.1|DBSCAN-SWA
MITVKAAAPDEGQQYFVLIFDCGGDHQVRTRLKEEHQGLTEAGYEKIICIRDVRPDFSRAEIAQLAAGLEKGLIPGLVPVDFILSTMELEAWFLAEFNHYVKIDPLITNEAIFAAIGFDPAIDDPATRDEPANDLRQCYALGGKTYEKSESGRTISALDYAYIYTNLVCRIPEIQRIANHIDEFLTPA
>NZ_CP051487|2486844:2587244|2525337_2527425_+|WP_168757722.1|DBSCAN-SWA
MANKGYSLDVVIKAVDKLTAPLRGMFSKVKQASAGVTGALDRTGLPVFANSLKGVGGAIGGIGTAVSSSAKKILGLGATLGITGAALNLFFQGFADATGAIGDTAERTGISRERFQELSFAAKLTGSSAETLGGALQKMQINVGKATAGSKDLKEMFKGLGINIKDSSGKLKSTDALFDTFVNRISKIKDPSLQAEAAVKIFGKSATELLPLIRGGGAGIKDMADEARRLGIVISDSAVREGETFGDTLDTLHTALSGVGNSIGSSLVPQLNILGSKLIDNIVKYRPQIEAFATSFAENLPGNIEKVTGFINDLYDGIQPVIKVIGELSDTFGGANIVLAVLGAYIGGGLLVSLVSLVGAIKTVGVALLTTPVGWFLLAVLAIGAAAYVIYKNWDGLVAFFTEKWAGVKAAFSDGIINGIVKLWLEYNPVTLMMEAFNGLVQYLTSWDLSAIIGTKFSAIVKVWNEYNPVALIQVAFNGLVQYLTSWDLSAIIGAKFNAIVKVWNEYNPVTLMQEAFNGLVQFLSAWDLSAILGTKFSAIVNVWLEHNPVKLMMESFGGLIKYLTGWDLGAILGSKISDAVAALKNGLPDWAKKLLGIDGASMGDVTGADPGTSSVAAALATDPNAALGPRRSVTELGQRAAQVGQTAAQAVEQPAQKVLVQVDMNNLPPGTKVKTEGSQGATFDTDLGYSMMAP
>NZ_CP051487|2486844:2587244|2553199_2553400_-|WP_168757756.1|DBSCAN-SWA
MRVLSPHITIDQALEALEHPGSRDIDDSLANGLLVRLFTAGDITVEEFHHYSARLLKISRKRKELS
>NZ_CP051487|2486844:2587244|2499554_2499902_-|WP_168757689.1|DBSCAN-SWA
MPIPTDTAEFLEELNGGAFASQIGHALSEVASGVVDHGKAGKLVITLDFSQIGESSQVKIKHKLDYKVPTKRGTRSENTSLDTPMHVGSGGKITLFAEKHDQLFSREQAPITPRT
>NZ_CP051487|2486844:2587244|2504287_2504521_-|WP_168757696.1|DBSCAN-SWA
MTLKKPDQDLKRDLQGIASDLKWSAVELKRIAERLSLAGNEIDAQAIHHLITIFKAGEARLNARSAEISTRNPESLA
>NZ_CP051487|2486844:2587244|2509298_2510579_+|WP_168757703.1|integrase|DBSCAN-SWA
MTSAAVKMSDAEIKRQASGNVRDLRDVENRGLYLRFTKARARASWYLVTKGEWNLIGSYPDLNTKQVVAALPAIRLRLEAGTGANLSKWVNVGELLTWYAERMSRDRNLSSKRKKTGASAIKCHLIPRLGELPLTGIDKATLDSQLMWPLQESISIDYVRSVFQLLALAFRQAFKLGLISANPMATIKFSDFSKAKVGIKPSRLRGVQLSGLLEQLAAVMEPAPLDAMLALMMLCHGTRIGETRQARWSHISLAEREWFIPAEHTKTGVEHHLPLTEQVCALLVSYREGQYAKGYDGQFLFPARNGKALSEGQASAVFVRLGQGEWTSHDLRKVARTGWADIGIDYLIGELLINHAMVHNVKVYIQSDVMSRKRDALEQWHAHLDQKGFALIHGLTGFRTGDSGNALEAAEHKGCEANQESTIGEV
>NZ_CP051487|2486844:2587244|2513851_2514397_+|WP_168757711.1|DBSCAN-SWA
MAKNETTKQRGWLNKSEMASSLGISPQAFDKWGVAPVARIGREAFYTVQNVVENRVDHSQRKQQPAGEGTEGVDPMIEYKLLEERRGLTAAQRIAQEKKNLVLDKQLVPVPFATFALAKIAAQIGSKLDTVGKTVTRRHPEVDPRIIESVEREIALARNIAASFGEQLPELLDEYVESMAE
>NZ_CP051487|2486844:2587244|2516520_2518041_+|WP_168757714.1|portal|DBSCAN-SWA
MSMLDSLFPGYAAKRSDARLKKLRTEMTMDLIKRRFEGAAGGRRNDRWRATGADANAENAPALAKLRNRARDQRRNNPFAERAITGIADNAVGAGIVPLPLAKRDRDGLRLMDLWKAWAETTCCDADGLEDFYGLQHMIMEAVAESGECLIRRRRRFSSDGLPVPVQLQVLEADFLDENKAAILGLNEVIQGVEFDALGRRVAYWLFDKHPGSNATWGSLQSTRVPAEDVIHVFLRKRPGQARGYTWLAPVIQRMSSFDEMEDAVMEQAKIAACFAAFVTKDPETHTGVKKGPALIDRMEPGIVQELSMGEAVSFGTPPTFNGYTTYSWQALHAIAVGLGVPYELLTGDLKGVNFSSGRMGWLNFARRVDVWQWRMLIPQLCDQVWRWFMEAQVLLPGGVTDDVKAYWVPPRRDMVDPKSETENVITRVRNGLTTWPDALRELGITDPKRHAEQIQKANEMIDEYGLVLDCDPRRVAAAGSPSQPPTNEEKPDDANSESGDDKQDA
>NZ_CP051487|2486844:2587244|2500901_2501576_-|WP_020799057.1|DBSCAN-SWA
MTVDISNFIIATPLPISDTNPISLDLIGWRALIECPSVISMLPDGSLQMTAPTLGASSKSVHRTRCEWKEPGYWLFASAADHWCRQEMRLTKVNSLQKVVIGQIHVQGSERPPVKVFWNKGKITMGFRSSYLQDDPVNSTVLENVPLGALFKINIHANSSGAVSVSASCNGAKSTSAIMRLDNTWDTKTLAFHGGVYNQIDYSESTDPEDGSICVITDLSITHG
>NZ_CP051487|2486844:2587244|2538747_2539512_-|WP_168757737.1|DBSCAN-SWA
MKLKKACPFCSKSHPDIHFTKEHILRDKFNSLFPETPSHITWENKTRRSDGGFNIKPIVIPHGPFDSTVNSVCNECNAGWMNTLENHAESSLVELFYARRNFPSDDNLETLAFWAAKTAAVNALKHRDNLPGFPIDHYAIMKTQLKPPPLTYVWYCHTAFNQNTYFRYYRAGLPGKPESSFHITTINIGHALFSIIGSSTHEMNEELMPEIELRDRLYGRVWPEGARHSRPAVTIQDKSHLIKIGELISSHYLL
>NZ_CP051487|2486844:2587244|2499992_2500307_-|WP_168757690.1|DBSCAN-SWA
MIGVPMPNPRDSLIANLNQQLDQFFGAGRTAQEIAAGVTGEKEAMFGTSHSNKLRIERNKQAPRLKVLADAGYTVIEAAKTMGMETKRARLISRENNIKFPGPP
>NZ_CP051487|2486844:2587244|2512305_2512635_+|WP_168757708.1|DBSCAN-SWA
MDLLHRLFDKAEWLVAGLIGAIVASWWHKDDLTDWRAWAIFLVTGVACSLYLTGMVSAYLGVTEPSIVAGIGFLLGTFGGSLLAAINRAIKAADLWALIRQRFGGGNPP
>NZ_CP051487|2486844:2587244|2571538_2572669_+|WP_168757782.1|DBSCAN-SWA
MAYPAESIINITTLINSAGLGTSNFGAGMVFADFDSSSDATFAEGSFRDYGSPSQVAAQFNIASDPYAAALAWFSAVPKPKTLRIYLRIEEDTPVESFNDAINKGIWFYWYEFETSIRADDAVVLALGAAGDAAGKFFAYTTNQATVRDPAATTDIVSKAVTQGSRRMLVASHATELYEGFEIAAVFSRVNFNAANSAITGEYKKLPGIDAESLTPTAYGAMKQKGAVFYTVVETGGERDAGRIINSKTTSANGEYIDDVFNLDAFTNVMTVALYNALTKVPTKLRQTPAGQQVLIDAAAQVGEKFIGNGYLGERLYIDEETGEEKLSRGYQILTKADDILLISDAERAARGAAPIVMRIFRAGAIHTVDLTANVE
>NZ_CP051487|2486844:2587244|2553387_2553828_-|WP_168757757.1|DBSCAN-SWA
MNALARAQAAYDSRLPPDDGDSVLETSEAQEWVIEATQGLIDGHPIVAPSPYGRGATLASREHLARDVDEHLQATPDFERNVAQILIEIVSCGDTESRLYKLAHGALGYSDDCVVTRLAREMAERNADAYFDAKCEQDRAETECGF
>NZ_CP051487|2486844:2587244|2534387_2534612_+|WP_168757729.1|DBSCAN-SWA
MVLVLAQLLQTVGQPPPVQVVVRLLVVAALHNAPETLAVILAFLGILVAAARAVPVHTTPAGPAGSAVKVVKAS
>NZ_CP051487|2486844:2587244|2506193_2506475_+|WP_168757699.1|DBSCAN-SWA
MDRLQISRLALVPVSGLEEEMVMGVVPDRAVEASIAGIGRHGQNIGLAVDSSSAEMTGTKKPVARPASSKRKTLRGHYEHDRRSKQYGHHVEP
>NZ_CP051487|2486844:2587244|2573083_2573530_+|WP_168757784.1|DBSCAN-SWA
MSDAASHIRSIEHDGVTYRFAMPSAEKQRAVLFRLGKYGVEPMIRGLALAEVGAASSFMVAGGIVGTMLSRMPEDDFNFVCDSMLGKLFKEGSATPVTMEDFSGRLKTYFTLVVMALGNVFEDFTGLLTLFQKSTDSAEVVGSSQEPG
>NZ_CP051487|2486844:2587244|2574586_2575615_+|WP_168759162.1|DBSCAN-SWA
MAALRALIGLGGSGATAGAAAAAGGASLLAVAGGSAAALFYSRKLNENEDIELLNNKLKKGGTEAAGATIDFFRSKGWTEEQAMGITANIEQESGFKHDVEGDGGQAYGLAQWHPDRQADFAKFSGKDIRQASGAEQLEFINHELTRGKEKAAGEKLRVTSTPSEAAGVVSKYYERPADHEGEAERRGEMADTYGRSAPKDTQASSAPAVDLSDPVVWARVQKELKQSGAPQESMLDQAKTWLESHRKTSQPQPAYGAAEAWNPAQREAPREYTVNAVVQSSPQAPITPAQSQAAPTAQPSYVDNRQFNIHGADTEKVKQLYTEQLSKLTEQTMQDFRSPEK
>NZ_CP051487|2486844:2587244|2564536_2565943_+|WP_168757773.1|DBSCAN-SWA
MTEAKPRIKIKAVMVPTTDSLSNLVANLGTGRDKRTHNSFGFEFVNQFELEAAYQSNWIARRIVDKPNEDALREWRKFSGKQSKQIESEERRLGVQQAYLDTCCWADLYGGAALLMVTGQDLSKPLDLNKIKKGGLKNLVVLDRWDIQPIKFNLEDPLKPNWMQPESYMMVNGTQDIHYSHIVRRTGARLPRRMRMFEQGWGDSRLRRCMSDLRDVVATKGGIASLVLEANVDTIGVKNLQGALASAQSSQVTERYRLFGMLKSIVNLGLLDMDNEKYERNSISFSGLSQIMEQFMVWTAGAAEMPVTELWGQSAAGLSSTGEGDLKTYHGTIKGKQDGQMRLDLEALDQVLIRSALGRYPDGIEFEWNPLSLPSGNEQAQEDLADAQADAVNIESGVIRPSHAMRRAQGKGTYAITDEQIKAQEQIEKDQDNGLGDDGKDLPGFSLGETDGDKPGADGKTPEKAEGA
>NZ_CP051487|2486844:2587244|2512984_2513725_+|WP_168757710.1|DBSCAN-SWA
MVRIDAGTNVEELSKALRTLGAKQLPFAFALMATKLAMLVKKGELSVMRERLDRPTATTLNSLYVKAAKKGNPEARTFFKDAWTSGVPADTYLQQAVKGGRRPHKRFEKALIAKGLMNSGQYAIPAPSAVNQFGNVPRGTIMKILSGLGAAETVSGVQANATGSKRSKRKGNADKYFSGDVDGTQGIWERKKTAFGDAVRPVFIFSDSEPGYRVIVPFYKIADNIVKANREREFASAMDQALSTAR
>NZ_CP051487|2486844:2587244|2493778_2494135_+|WP_003179985.1|DBSCAN-SWA
MLEPSHNDELPVIPGKRYFTIGEVSELCAVKPHVLRYWEQEFPQLNPVKRRGNRRYYQRQDVLMIRQIRALLYDQGFTIGGARLRLSGDEAKDDTTQYKQMIRQMIAELEDVLVVLKK
>NZ_CP051487|2486844:2587244|2546742_2546892_-|WP_168757745.1|DBSCAN-SWA
MIRRPDGSTVSINTEHGRHTGEVAAARQEITRLPHGELECKAAQFAIFA
>NZ_CP051487|2486844:2587244|2507878_2508562_+|WP_168759158.1|DBSCAN-SWA
MKTVSVIAQDLWAKAQSGEFIAAGDVPPVANGAHSTLVTAINELFKELRSIRSAWRQAWPDKETYRASKRQWFQAFLEEGICTQGQIDFGMTQVRKQPGDFIPSPGQFIEWCKPTPEMLGLPPLAAAHREACRNAHPGMAGQGKWSHDAVWHTAKECGFESLNKLDTPLSLKLFERNYTITIRRLLAGLPLQAMPKALPARAAGRATPEVGQGALAQLRAKLGGARD
>NZ_CP051487|2486844:2587244|2520083_2520434_+|WP_168757716.1|DBSCAN-SWA
MKTFIQRGDCLTVIAPAGGTVSGELYKVGSVIGVAATTEVAGAPVVLKLEGVFGLNKISAQAWAVGDLLYMNTTSRVLTNVSATGLVLVGMATEIAANPSATGACRLNGVSAPAPV
>NZ_CP051487|2486844:2587244|2537222_2537912_-|WP_168757734.1|DBSCAN-SWA
MCGRLSQYDGIHDFVAALSMPNPLVNNTGDRPFERYNAAPTTQLAIFHQEGEYLHADMVRWGWRPHWAKDRVAPINARVEKVAHGPFFRDIWPHRAIIAINNWFEWVDEGGPKKQPYLIRRRDRSPILCAAIGQYPNAEHEPSVHDGFVIITADSAGGMVDIHDRRPVTLSPELAREWLDPATPKERAEQMVMHQGEPTEAFEWFKVDRAVGNVRNQGPALIDPLATPS
>NZ_CP051487|2486844:2587244|2494921_2496037_-|WP_168759156.1|integrase|DBSCAN-SWA
MVPRPRNPANKGLPQNLYYDARRSTYRYRRPTDGKWFPFGADRVKAIDAAKQLNLEFMRGADLVGAVMGRTSDLFTGFLDIYERDVLPPRDLAKGTLGLYAVHFRRFRKHFEDKAVDQITIRMIAEMLDALTPRTANQCRALLIDIFNHAAAKGLCPDNPATSTINRIEKKQRKRHTIEGLKAIREKSPAWLQNAIDLALITAQRRTDILNMRFDGVREGFLYVVQQKTAKATDAAWIRFKVTDELQAVISRCRDDIVSPYLVHRRPDRKKQKQAQTKDHWTQVEERYLTRAFKAAREAAECYKGWKEEEMPGFHEVRALSLHLYQKAGKDGQKIAGHASESMTKNYQRDHAEIVWSEAIPDLDISEIAGT
>NZ_CP051487|2486844:2587244|2501923_2502316_-|WP_168757692.1|DBSCAN-SWA
METEIVNGAWKGHLGRGLAPRELQFLLWVALGLTAKEIAREAGISPATVAKRLTNAMFKLGVTRRAALVAEAMRRQIISPMCFVLATLMTMNAVTNIQSVEPARRDRRPPSVRIAQIRITRRAETLERAA
>NZ_CP051487|2486844:2587244|2489601_2489958_+|WP_007905879.1|DBSCAN-SWA
MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARINGLSYSRFIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKATLA
>NZ_CP051487|2486844:2587244|2566808_2567918_+|WP_168757774.1|DBSCAN-SWA
MKKMSLDEAFKPTSRTVTPEGFLCVKGVAARTGVYQYVSTELDLDGPERIVNVYRPPAQVFAPESMATFPDKDVTNDHPDDLVDSTTFKEVSVGHVRGVEQDGDNLVVDLIIKDQSAIDDIQSGKAELSPGYLAEYVEAPGIDPVSGTAYEFEQRDIQINHVAVVEAARGGKVARIFDHKPKGVPMAQRKVFLDSKKSRSITVDEEVALVVEDAVAALQKFADEESERADKAEATKDEAEEKLEEAKKETSDAAIGARVKSTLDTIALAARVVKSFDAKGLVSPLEIKRVAMAQLKPTRDWATKSEAYVLAAFDAAADEAEETKDEDEDDDKSKVNDSLKRFAEDAAKRGLKPTQDGTDAYNKYLRGEK
>NZ_CP051487|2486844:2587244|2543558_2544170_-|WP_168757742.1|DBSCAN-SWA
MNVMHFYTTSTTEPAAGYVSEGITANVLNHQTEDASAFNRWRHPESNLHFYTTDPNGEAAPAAGYVFEKIECYVPNPGVPGTIPLYRWYNPNTGDHLYTLDKDGELGPASGYVAEGISCYVFPLGSDGTVPLYRWVAGDQTWCIRLSRSSPDGHRYVVFSKNVHVSTYEEAKALAQIVYDQYNFQSLPEMTANFIEEPKLGGC
>NZ_CP051487|2486844:2587244|2527437_2528766_+|WP_168757723.1|DBSCAN-SWA
MTWRDTYRAATFRGVAFFVESADSSHGRRQAVHETAQRDTPYTEDLGRKSREFSVVGYLLGKDYHLNRDELIKACEVAGPGALVHPYRGEMNVVCRGLNISETAAEGGKCTIALTFLEAGEAAYPSANVDSVNAISAKGNTVTAAAESSFLSDFLTTGFPAYVAESAASGLAGLGEYMAAPGLNFSGDLKAASDFYLQARGLVSDASSLVQKPLNMVSRITGLIGSVRSAFGANAFSMLTSLFDRSPRTYTGSTATPSRQQQATNAIAMNALVRQVAVAEAAKAAVVTQTPVVTTTAVTQASTGVPRTALGIPQGSKRATQTAPGVTQTLPVPTVYDSYQAAIKVREDLVDRIDAESEVTPNDEVYVALSDLRTSVVQAVPNPEQNLARIVQYVPRETLPSLLVAYQIYGDAGRADDISNRNSARHPGFLMGGQQLEVLADG
>NZ_CP051487|2486844:2587244|2566010_2566805_+|WP_168759161.1|head|DBSCAN-SWA
MATDLIASLEPALKRLKPDYIADSRVTLDGSWTDEILKSIRSVSQRFTSPLFEAQIQRVAATTISRADADNAEDFRDSINKAVGIDFQLVTKPKGMTDFLEASTAENVNLIKSIPADYFKKVETIVLGGMKDGLAPTTIAKQIQEETGVSARRAKLIARDQVSQLNSDLTRQRQTAAGIVHYKVQDADDVRVSGNPSGKYPNAKISCWGIARQDIGYGPGVYKVAEGATWKGVTNLHPGKHHPLCRCIGIAMIPGVNYFPDKNG
>NZ_CP051487|2486844:2587244|2505740_2505944_+|WP_020799051.1|DBSCAN-SWA
MAYDDKAHRHEHQVKVRLDDEVFQELKDVARDMKLQHSVLSREIIEAALEVKRTLGELPFELEKRRA
>NZ_CP051487|2486844:2587244|2536183_2536735_+|WP_168757732.1|DBSCAN-SWA
MPITKQQLLQILPNAGKQAGVFASALNLAMDRFQINTRMRVAAFIAQVGHESGQFRYVRELGGDQYLSKYDTGPLAKRLGNTPEADGDGQTYRGRGLIQITGHDNYLACSKALFSDDRLLRTPELLEQAEWAAKSAAWFWHSRNLNALADAGDFVGVTRRINGGTNGMVERHSFYSTALKVLA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008066670.1|2486844_2488767_+|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	4.5e-124	37.3
WP_015095841.1|2488784_2489318_+	translation initiation factor IF-3	NA	NA	NA	NA
WP_002553160.1|2489378_2489573_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_007905879.1|2489601_2489958_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_020799067.1|2490067_2491084_+|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.1e-28	39.3
WP_033042613.1|2491110_2493492_+|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_002553164.1|2493495_2493798_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	1.8e-11	38.9
WP_003179985.1|2493778_2494135_+	MerR family transcriptional regulator	NA	NA	NA	NA
2494254:2494303	attL	NA	NA	NA	NA
WP_168757685.1|2494354_2494921_+	hypothetical protein	Q9ZXJ6	Pseudomonas_virus	1.3e-15	32.1
WP_168759156.1|2494921_2496037_-|integrase	tyrosine-type recombinase/integrase	A0A0U4JIT5	Pseudomonas_phage	1.4e-32	32.3
WP_104449552.1|2496036_2496249_-	hypothetical protein	NA	NA	NA	NA
WP_168757686.1|2496787_2497879_+	ATP-binding protein	NA	NA	NA	NA
WP_168757687.1|2498013_2498580_+	hypothetical protein	NA	NA	NA	NA
WP_168757688.1|2498712_2499528_-	DUF2303 family protein	I3PUY7	Vibrio_phage	6.9e-42	38.4
WP_168757689.1|2499554_2499902_-	hypothetical protein	NA	NA	NA	NA
WP_168757690.1|2499992_2500307_-	hypothetical protein	NA	NA	NA	NA
WP_168757691.1|2500303_2500585_-	hypothetical protein	A0A2H4J404	uncultured_Caudovirales_phage	4.2e-07	47.1
WP_020799057.1|2500901_2501576_-	polysaccharide lyase family 7 protein	NA	NA	NA	NA
WP_168757692.1|2501923_2502316_-	helix-turn-helix transcriptional regulator	A0A2H4JA92	uncultured_Caudovirales_phage	1.4e-19	55.4
WP_168757693.1|2502735_2503047_+	DUF1654 domain-containing protein	A0A2D1GND3	Pseudomonas_phage	6.3e-28	63.4
WP_168757694.1|2503179_2503401_+	hypothetical protein	NA	NA	NA	NA
WP_168757695.1|2503808_2503988_-	hypothetical protein	NA	NA	NA	NA
WP_168757696.1|2504287_2504521_-	hypothetical protein	NA	NA	NA	NA
WP_168757697.1|2504525_2505407_-	helix-turn-helix domain-containing protein	A0A2D1GNH0	Pseudomonas_phage	2.6e-71	62.4
WP_168757698.1|2505512_2505707_+	Cro/Cl family transcriptional regulator	A0A2H4J1L8	uncultured_Caudovirales_phage	7.0e-09	53.1
WP_020799051.1|2505740_2505944_+	hypothetical protein	NA	NA	NA	NA
WP_168757699.1|2506193_2506475_+	hypothetical protein	NA	NA	NA	NA
WP_168759157.1|2506461_2507130_+	DNA-binding protein	A0A1B0YZY9	Pseudomonas_phage	4.8e-65	60.9
WP_168757700.1|2507129_2507882_+	hypothetical protein	A0A2I2MUI8	uncultured_Caudovirales_phage	3.8e-111	80.7
WP_168759158.1|2507878_2508562_+	Replication protein P	B5WZY0	Pseudomonas_phage	2.8e-44	50.8
WP_168757701.1|2508554_2508758_+	hypothetical protein	NA	NA	NA	NA
WP_168757702.1|2508870_2509302_+	VRR-NUC domain-containing protein	A0A2D1GNH3	Pseudomonas_phage	1.1e-46	67.1
WP_168757703.1|2509298_2510579_+|integrase	site-specific integrase	A0A2D1GND4	Pseudomonas_phage	2.1e-122	55.1
WP_168757704.1|2510581_2511094_+	hypothetical protein	NA	NA	NA	NA
WP_168757705.1|2511093_2511414_+	hypothetical protein	A0A2D1GNG3	Pseudomonas_phage	1.3e-39	73.6
WP_168757706.1|2511417_2511771_+	antitermination protein Q	A0A2D1GNB4	Pseudomonas_phage	2.6e-54	84.6
WP_168757707.1|2511867_2512101_-	hypothetical protein	NA	NA	NA	NA
WP_168757708.1|2512305_2512635_+	MFS transporter	A0A088FVG2	Escherichia_phage	1.9e-19	44.9
WP_168757709.1|2512631_2512976_+	hypothetical protein	A0A193GYR7	Enterobacter_phage	3.6e-08	41.0
WP_168757710.1|2512984_2513725_+	hypothetical protein	NA	NA	NA	NA
WP_168757711.1|2513851_2514397_+	DNA-packaging protein	A0A1B0Z033	Pseudomonas_phage	1.3e-65	70.4
WP_168757712.1|2514368_2516306_+|terminase	phage terminase large subunit family protein	A0A1B0Z2K0	Pseudomonas_phage	3.3e-292	73.9
WP_168757713.1|2516314_2516524_+	hypothetical protein	NA	NA	NA	NA
WP_168757714.1|2516520_2518041_+|portal	phage portal protein	B7SYD6	Stenotrophomonas_phage	7.5e-74	38.2
WP_168757715.1|2518048_2520004_+	hypothetical protein	A0A2I7S8L6	Vibrio_phage	1.7e-86	32.3
WP_168757716.1|2520083_2520434_+	DUF2190 family protein	NA	NA	NA	NA
WP_042955929.1|2520788_2522057_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_168757717.1|2522329_2522884_+	hypothetical protein	NA	NA	NA	NA
WP_168757718.1|2522880_2523072_+	DUF2635 domain-containing protein	Q8SBH3	Shigella_phage	2.1e-05	53.2
WP_168757719.1|2523068_2524541_+|tail	phage tail protein	A0A0C4UQS0	Shigella_phage	6.2e-81	39.8
WP_168757720.1|2524566_2524935_+|tail	phage tail protein	NA	NA	NA	NA
WP_168757721.1|2524934_2525237_+	hypothetical protein	NA	NA	NA	NA
WP_168757722.1|2525337_2527425_+	hypothetical protein	A0A2I7QYY1	Vibrio_phage	9.8e-16	26.3
WP_168757723.1|2527437_2528766_+	hypothetical protein	J7FAD8	Agrobacterium_phage	2.7e-11	21.7
WP_168757724.1|2528758_2529883_+	hypothetical protein	M1PVV2	Vibrio_phage	2.9e-54	36.7
WP_168757725.1|2529879_2530395_+|plate	phage baseplate assembly protein V	A0A0C4UQZ3	Shigella_phage	6.6e-14	34.7
WP_168757726.1|2530394_2530862_+	hypothetical protein	Q8W616	Enterobacteria_phage	3.9e-13	36.9
WP_168757727.1|2530861_2531920_+|plate	baseplate J/gp47 family protein	A0A2P9JZK6	Alteromonadaceae_phage	1.9e-63	40.4
WP_168757728.1|2531928_2533737_+	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	1.0e-45	49.5
WP_168757729.1|2534387_2534612_+	hypothetical protein	NA	NA	NA	NA
WP_168757730.1|2534631_2535033_+|tail	tail fiber assembly protein	NA	NA	NA	NA
WP_168757731.1|2535075_2536128_-	acyltransferase	NA	NA	NA	NA
WP_168757732.1|2536183_2536735_+	glycoside hydrolase family 19 protein	B5TK83	Pseudomonas_phage	3.6e-66	67.6
WP_168757733.1|2536731_2537265_+	DUF2514 domain-containing protein	A0A077KH21	Edwardsiella_phage	5.4e-11	39.2
WP_168757734.1|2537222_2537912_-	DUF159 family protein	A0A2H4J991	uncultured_Caudovirales_phage	5.0e-110	80.0
WP_168757735.1|2537914_2538235_-	hypothetical protein	NA	NA	NA	NA
WP_168757736.1|2538315_2538525_-	hypothetical protein	A0A1B0VP78	Pseudomonas_phage	2.8e-11	55.4
WP_168757737.1|2538747_2539512_-	hypothetical protein	NA	NA	NA	NA
WP_168756983.1|2539731_2539875_-	hypothetical protein	NA	NA	NA	NA
WP_168757738.1|2540347_2541544_-|integrase	tyrosine-type recombinase/integrase	A0A059VF45	Pseudomonas_phage	3.3e-157	69.8
WP_168757739.1|2541943_2542357_+	hypothetical protein	NA	NA	NA	NA
WP_168757740.1|2542454_2543048_-	morphogenetic protein	H2BDG4	Pseudomonas_virus	1.1e-39	49.3
WP_168757741.1|2543044_2543359_-	hypothetical protein	A0A059VA44	Pseudomonas_phage	4.9e-44	72.1
WP_168757742.1|2543558_2544170_-	hypothetical protein	NA	NA	NA	NA
WP_168757743.1|2544335_2546405_-	DNA cytosine methyltransferase	Q5QF27	Pseudomonas_virus	2.5e-229	59.6
WP_168757744.1|2546488_2546722_+	hypothetical protein	NA	NA	NA	NA
WP_168757745.1|2546742_2546892_-	hypothetical protein	NA	NA	NA	NA
WP_168757746.1|2547028_2548036_-	nucleoid-associated protein YejK	L7TI92	Pseudomonas_virus	3.6e-125	66.3
WP_168757747.1|2548115_2548364_-	hypothetical protein	NA	NA	NA	NA
WP_168757748.1|2548513_2549254_+	hypothetical protein	NA	NA	NA	NA
WP_168757749.1|2549250_2549448_-	hypothetical protein	NA	NA	NA	NA
WP_168757750.1|2549465_2549822_-	hypothetical protein	NA	NA	NA	NA
WP_168757751.1|2549823_2550297_-	single-stranded DNA-binding protein	A0A088FAZ2	Sulfitobacter_phage	1.5e-09	39.7
WP_168757752.1|2550306_2550924_-	YqaJ viral recombinase family protein	A0A1B0VMB3	Pseudomonas_phage	1.7e-96	82.4
WP_168757753.1|2550907_2551690_-	single-stranded DNA-binding protein	A0A125RNR3	Pseudomonas_phage	2.6e-54	47.5
WP_168757754.1|2551697_2552852_-	hypothetical protein	W6MYA7	Pseudomonas_phage	2.9e-41	69.8
WP_168757755.1|2553008_2553203_-	hypothetical protein	NA	NA	NA	NA
WP_168757756.1|2553199_2553400_-	hypothetical protein	A0A1B0VMB8	Pseudomonas_phage	2.1e-08	45.9
WP_168757757.1|2553387_2553828_-	hypothetical protein	NA	NA	NA	NA
WP_168757758.1|2554197_2554656_-	hypothetical protein	NA	NA	NA	NA
WP_168757759.1|2555090_2555468_-	hypothetical protein	A0A1V0E899	Vibrio_phage	1.7e-14	38.0
WP_168757760.1|2555652_2556174_-	hypothetical protein	NA	NA	NA	NA
WP_168757761.1|2556324_2557191_-	damage-inducible protein D	F5A3D6	Riemerella_phage	1.2e-52	43.6
WP_168757762.1|2557340_2557529_-	hypothetical protein	NA	NA	NA	NA
WP_168757763.1|2557555_2558371_-	LexA family transcriptional regulator	A0A2H4J6Q0	uncultured_Caudovirales_phage	5.1e-77	57.6
WP_168757764.1|2558479_2558674_+	hypothetical protein	A0A2H4J1L8	uncultured_Caudovirales_phage	3.1e-25	89.1
WP_168757765.1|2558704_2558893_+	hypothetical protein	B5WZX7	Pseudomonas_phage	9.1e-14	62.9
WP_168757766.1|2559162_2559369_+	hypothetical protein	NA	NA	NA	NA
WP_168759159.1|2559724_2560483_+	phage antirepressor protein	A0A059VF66	Pseudomonas_phage	6.8e-68	58.1
WP_168757767.1|2560479_2561268_+	DUF1376 domain-containing protein	A0A059VF77	Pseudomonas_phage	1.8e-31	66.3
WP_168757768.1|2561267_2561927_+	Replication protein P	W6MVG8	Pseudomonas_phage	2.1e-60	55.9
WP_168757769.1|2562023_2562494_+	hypothetical protein	A0A2H4J106	uncultured_Caudovirales_phage	5.4e-55	64.7
WP_168757770.1|2562490_2563081_+	recombination protein NinG	A0A059VA66	Pseudomonas_phage	3.6e-72	69.0
WP_168757771.1|2563077_2563659_+	hypothetical protein	A0A059VF83	Pseudomonas_phage	3.8e-74	68.4
WP_168759160.1|2563947_2564280_+|holin	phage holin, lambda family	A0A2H4J1U5	uncultured_Caudovirales_phage	4.0e-28	56.0
WP_168757772.1|2564283_2564478_+	hypothetical protein	NA	NA	NA	NA
WP_168757773.1|2564536_2565943_+	DUF1073 domain-containing protein	H9C192	Pectobacterium_phage	4.0e-106	44.8
WP_168759161.1|2566010_2566805_+|head	phage head morphogenesis protein	A0A2I7QN95	Vibrio_phage	2.4e-55	42.6
WP_168757774.1|2566808_2567918_+	DUF2213 domain-containing protein	H9C194	Pectobacterium_phage	1.8e-53	48.8
WP_168757775.1|2567917_2568427_+	DUF2190 family protein	NA	NA	NA	NA
WP_168757776.1|2568437_2569415_+	DUF2184 domain-containing protein	A0A2I7QN78	Vibrio_phage	2.4e-33	32.6
WP_168757777.1|2569424_2569607_+	hypothetical protein	NA	NA	NA	NA
WP_168757778.1|2569657_2570092_+	DUF4054 domain-containing protein	B5AX60	Iodobacteriophage	3.4e-11	39.0
WP_168757779.1|2570088_2570586_+	hypothetical protein	A0A2I7QQZ3	Vibrio_phage	3.8e-35	47.8
WP_168757780.1|2570585_2571005_+	hypothetical protein	A0A1I9SEU3	Klebsiella_phage	4.2e-11	35.4
WP_168757781.1|2570997_2571555_+	hypothetical protein	A0A2I7R3Y3	Vibrio_phage	6.7e-12	28.1
WP_168757782.1|2571538_2572669_+	DUF3383 domain-containing protein	N0DP63	Edwardsiella_phage	2.3e-75	42.7
WP_168757783.1|2572682_2573087_+	hypothetical protein	L0ASG3	Klebsiella_phage	1.3e-17	40.6
WP_168757784.1|2573083_2573530_+	hypothetical protein	NA	NA	NA	NA
WP_168759162.1|2574586_2575615_+	hypothetical protein	NA	NA	NA	NA
WP_168757785.1|2575611_2576232_+	hypothetical protein	A0A1I9SEV5	Klebsiella_phage	1.0e-21	34.6
WP_168757786.1|2576228_2576531_+	hypothetical protein	A0A2I7R3Z4	Vibrio_phage	5.0e-06	38.8
WP_168757787.1|2576523_2577477_+	hypothetical protein	A9YX04	Burkholderia_phage	4.1e-17	26.2
WP_168757788.1|2577473_2578148_+	hypothetical protein	N0DPE2	Edwardsiella_phage	1.2e-26	38.6
WP_168757789.1|2578144_2578510_+	hypothetical protein	H9C1B2	Pectobacterium_phage	1.4e-13	39.8
WP_168757790.1|2578509_2579769_+|plate	phage baseplate protein	A0A2I7QR17	Vibrio_phage	2.1e-66	39.1
WP_168757791.1|2579765_2580425_+	DUF2612 domain-containing protein	B5AX81	Iodobacteriophage	2.6e-23	35.6
WP_168757792.1|2580424_2581450_+|tail	tail fiber protein	A0A1L7DQA4	Ralstonia_phage	6.5e-13	46.9
WP_168757793.1|2581446_2581638_+	hypothetical protein	NA	NA	NA	NA
WP_168757794.1|2581646_2582096_+|terminase	terminase small subunit	E5AGA2	Erwinia_phage	8.8e-31	53.6
WP_168757795.1|2582092_2583703_+|terminase	phage terminase large subunit	H9C191	Pectobacterium_phage	2.2e-148	47.4
WP_168757796.1|2583770_2586458_+	hypothetical protein	NA	NA	NA	NA
WP_168759163.1|2586596_2587244_+	glycoside hydrolase family 19 protein	J7I4M6	Pseudomonas_phage	1.9e-66	62.7
2589507:2589556	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP051487|2991139:3032300|DBSCAN-SWA
CTTGTTGAGCGCCGGCCAGGGACGACGGCTTCTTCCCTATACGACGAACACCCCCAAGTGCCTGATCGAGGTCGGTGGGCAGCGGGTCATAGAGTGGCAGATCGATGCTCTGATGGCCGCCGGGATAAGCCGGATCACCGCGGTCATCGGCTATGGAGCAGAGCAGGTCGAACGGGTGCTGAACGAACGTTACGGGCCTGGCGTCATTTCCACGATCTACAACCCGTTCTTTGAAGTTGCCGATAACCTGGCCAGTTGCTGGATGGCTCGCCAGATCATGCATGACGATTTCATCCTGCTTAATGGCGATACGTTATTCGACCACCCAGTCCTTGAGCGATTGCTTGATGCACCTGCCAGGGCGATTACGCTCGCGGTCGACAAGAAACTGGCGTACGACAGCGACGATATGAAAGTCCAACTGATCGGTGATCGAATCAGCGCCATCGGTAAACTGATTCCGCTCGATCATGTCGACGGGGAGTCTATCGGCATGATGCATTTTCAGGCCGGTGGAGGACCACTGTTTCGTAGTGCGCTGGAAGACAGCATGCGACGTCCTGAAGCCCTGCAAAGGTGGTACTTGAGCATCATCGATCACCTCGCAGGGACTACCGGGCAAGTGTTCGCGCAGTCCATCGAAGGATTGGGCTGGGCCGAGCTGGACTTTCCTGCCGATCTCAGAGCTGCGCAGGCACTGGTCAGGCCCTGGGTATGCCGCAAGCAAGGGACGGCAATTACCCTCGCGGAGGGAGAGTAGGGCTGCTCCTGAGGTTGGGGTTTCAAGCTCGTCTATCGACCAGGCGGGCAGTCACAATGAGACTCGATGCTGGGCTCAAAGGTGTCGCGCAAGGCAGAATATTCCCAGCGTTCGACGGTGACGCGCCTTGTTAGTTTGTCCAGATGGATTCGATTGAACGAATTGGGGGCATTGCCACGTAAACGTGACGAGAGGGTCGTTCCCGCCTGCACCCCCCATATTTCCTTGGACAATGCGCCGTATTGCGTGCTGAGTGCCAGCACATAGGGAAGATGGATGTGCCCCCCCATCACCAGGTCGAGCCCGGACGAGGCCCAGCGTTCCAGTGCAGCCCTTGCACCGATCTGCAGATTGCGTTGGTCGCTGGCGACGATTGCGCCGAACGGCTGATGAGCGACGACGATGCGCAGTTTTTGCGGATCGCATTTCTGTAGCCGTTCAGCCACTTCCTCGACTTGCCGGGCAGTGACCTTGCCATCTTTTCGGCGTGCCGGGTGGGTTGTGTTCAAGCAAATGATCAAGGCATCGTCATTCTCGAAAACGGGTGCGAGGTTGCTGTCGATGTACTTGTAATAGTTCCCGTAGGGTGAAAACAGGCGCGCGAACAGGTTGAACATGGGGATATCGTGGTTGCCGGGGATGGTCAGTACTTTCGGTATTCCATAGCCCTTGATGCGGTTGATGAATGCCTGCGCCGAGGCGAACTGCCCGCGTCTGGCGCGCTGTGTGATGTCCCCGGAGAAAAGGACCAGGTCGGCGCCGTGGGCCTTGACGTATGTTTCAAAGGCTTGCATGACGGGGAGCTGTTCGGTGCCGAAATGGGTATCGGAAATATGCAGGAGACGGGTCATCGTTGCTGGACATCCTCTATACCCGACAGGGCTTGGCGCTTAATTTGTCGTCCGTTGGTGCCACTGACCACGTTCTTTGCCACTGTTCATGGGGTGCCTCCATTTTTCGCATTGCGAGCAGCAACGTCTTCAGCGAAGCCGGCGGCTTTTGAGCAGGCGCCAGAGCAATGGCCAGCCGAAGAGCAGTGGAAAACGACGCAAGCGATGGGTCACGACGACAGGCTCACCCAAGTGGCGTTCCAGCTTCCATATGAGGTAGTCGACACCATTTTCGAAGGTGAAAAAGGATTTGACCAACCGCGCCACGTTCAAGGTTCTTCCCTGGACCCGCCGCCATTTCCACAGACGTTCATTACCTCGGCGCGTGGCCATCGGGCAAAGGTTGCGATATCTGTCTTCTTCGCCCGCGCAGGCCGCCATTTGCTTCACCGCAGGCGCGGCTGCCTGGGTGATGCGCGAATAATAGTCCATGTCATGCCTGACGAGCTGCCTGGGGCGATCAGCTGATTCAGGACGCAGCTCGGTCCGGTAGGTCAGCGACAAGGATTTCTCCCAAAGGGTGAAGCTGTCGAATCGATCCGGCAGCGTGGCGACACAGCGACCCATCAGGGTCATCACGGCTTGAGCCAGGGCGAAATGGATACGCTTGCGCGTTTCCTCGTCTTTGAAATAAACCAGCCGGCAGGGCTGGGCGAAGCGGGCCCAGAGGTAGCTTTGAAACCATGAACCGGTACCCGCCTCGAAGTCCTGCAGCGACAGGATGGCGCATTTGGCATGGAGTATTTGCCCATCGGCCGCCGCAGCCCTGACGAGGATCACCGTGGGTGGCAGCCAGGCATTGGCAAGCTGCTGCAAGCGCGAGTGATGAGCGTGAGCGTAGCTATCGACCAGCGCATACACATCGACCAGGCCATCGGTGAGATCGCCGTTGCGCAGGCATGAACCGTAGACCAGCAGCGCCACTAATGTATCGCCCAGGCGTGTGTGCAATGCCTGGACAATGGCCTGCACCTCGTCGGGCATCGGCTGCGTGCACTGCTCCCTGATCTGTTCAAGCAGCTTCGCAGGGGGCGGCGGGCAGGCTTCATGCATCATTGAGGCCCGAGCGGGGCGCGAACATCCGCACGATCAAGCGGTCGCGTTCAGCGCTCATGTCGATTCGGCTGAGCCAGGGCTGTGGCGGCTGGCCTCGGTGCTTCAAGACAAGGGCGGACATCGTGCGCACCCCCAGGATCAGCGTCGAGACGCAGGTCCAGACGGCCACCCAGATCAACGCCGTGTCATGGGCATCGAACGCCCATAAGCTGGTCAGTATGAGCAAGTTGGGGTTGCGCCGCGCGGTGATCAGCCGGTTGAGTGAGTCGAAGGGGCGCCAGAGAAACAGCGAAAAAGGCGCGGCCAGCTTGAACGCACCTTCGCAAACCCTGCCTGCGATATAGCCCAGGCAAATGGCCCAGAGCACAGGCTCGAGGGGTATGGCCGAATCCCAGGTCGCCTCGTAGCCCAATCCCCAGGCGATGTACCAGAGCGGCGGGTGAATCAGGTCCAGGCCATGGTCGAAAAGGTTTCCGAAGCGCGTGGAGGTCACGGTGACGCGTGCCAGCTTGCCATCGACCGTATCCAGGAACGTCATCAACCAGCCGGCCAGCAGGCCTGCGCCAAATAATCCATGCCAGAACAGAAAGCCTGCGGCGATGGCCAGGACATAGCTGGCTGCCGTGACCTGATTGGGACTGAGCCCCAGCCGCACGCACCAGACGGTGGCCCAGCGAGCAGGGACAGGCCAGATCGCCCGGGTGATGAAATCGGTGACGCCCTTGTAGGAGCCGTTGAACAGAGACTTCTCAAGATGCGCCTGGTTGGCGGCGGTGATCTGCGCGACCCAGGGAGGATCGAATTTGCGCAGTTGCGTCTGCATCGCGGTGGCCACGGTGCCGGGAACCACTTTGCGTAATCCGGCGACGGCGTCAGTGTCCAGGCTGGGCAAGTGGGCGAGCCGCTCGACACTGGCGTGGGCGGCGACAATGGTGCCGGTGCGCGGGTCCTGTAGCGCGATCTCAGGCGTTGCCAGCAGCCCCTGGAGCACGCGGTCGTCGTAAAGGTAATCCTCGCGCAGCAGGACCACCTCGCCTTGCGCCGGCAACGGATCGTTCGCGTTGCACAGATGGGCGTTGGGAAACTTTGCGAGCATACGGCCCACTCGCTCCCTGGAGGTCAGTCCCCACAGCCGCACCGGGCAGCTGCAGATCAGGTATACGGGAGTCTTCATGGTTGGTTGCGCCTGCGCCGAATCACATTGATTGAAGGAGCGGGCGCCAACGCCCTGTCCATTGAACAGCATGACGGTTTCAACGACTGCCCCGGTCCAGATACGCCACGATCACAATAGCCACTGCGAGCAAGACCAGGGCCGGCCCCAAAGTAGTGACCAGGATGTTCATTTTTAGCAGTAGACCGAGGTTTACGATGATCTGATTACTTACATAGACCATTAACCCGACCAGCGCACCCAAAGCCAGCCGTGCACCCAGGTTGGGCGAGCGCGGTTGTGCGAAGGCAAACGGGATGGCGAACAGGATCATCGCCAGGGTCAGGATCGGTCGCCCGAGCTTTTGCCACATCGCCATTTCATATTGTGCCGAGGGCTGGCCCGAGCCTTTGAGGTACGCGATGTAACGGTAGAGCTGGCGGGCAGACAGGCTTTCGGTCGGCAGCGTAATGTCGCCCAATCGCGCACTGCCAAAAATCGAACGCCAGGGCATTTGGTCGAGTTGTTGCGTCGTTTCAGCGCCCTGGTCCCACTGTTTCACCTGGACATTGTTCAAACGCCACTGGCCTGCGTCCAATATGTCCGCCGTCTCGGCAAAGATGTAGGAAACCAGTGAGCGGTCGTTATCGAACCTGAAAATCTCAATATTGACCGGCAACCGTTTGTGCGCAAGATTGCCAATACGGACGATCTGATCGTCCTGTCGAGCCCAGACACTGCCTTGATCGTTGCTCGCCTGCGCACCGGCGGCGATGGCTTCGTTGCGCAGCTCCAGGCCATTTTGCTGCAGGGGAGAGGCCACCCACTCATCCAGCGCCGCCCATGACAGCGCTAGCGCGAGACCGGCCAATGTCGCCGTGAACCCGATCCGGGCAATCGACAGCCCGGTGGCGCGCATGACCGTCAGTTCCCGGGTGGCTGACAATTGCCCCAGCGCGGCAATGCCACCCAGCAGGGCGATAAAGGGGCCAAGCTCGACGACACGGCGCGGCAGCGTCAGGAACACGACTTCGATGGCCTGGCTCAACCGATACCCGCCGGGCGCCACGTCGTCTAATTCACCCACCAGGTCGAGGGTGGTGAACAACGGTAGCAGCAGCGCTGCCGCGGCCGCAAAACCGAAGAACACATGGCGGGTAATGTAGCGATCGAGGACTTTCATCGGTAGCCGAACCGAAAGTTTGCCAGGTCGCGCGCCAGGAAAACCAGCAGCGCCAGGCTCATCAGCAGCGGCACTGTCCACAAGCCCGGATACAAGGGCAGGGTGCTGTTGCCCACCATCGTCTTGCAGATGTCCGCTGCGTAGTAGATCACCGCGAAGACGGCGGTCACGGGCAGCAGGGTCGCAAACCGTCCCTGCCTGGGCCGGGTACGGCTTAACGGAATGGCGAGCAATGCAAGGACCATGGCGCTTACACCCCGCGTCTGGCGCCATTGCAATTCAGCTTTGTCCGAGGGCGCGCTGGAAGCCTGCAGCACTTCGTTGGGGGCGGCCTTGCGCTTACCCTCGGCGGCCCGTTCGATGGGTAGCAAGTGCAGCCGCATATGCTCGAACTTTTCCGAAATGTCCCGAGAAGCACTGTGCTTGAGCAAATAGGAATGGCCTTGCGTCAACTCCACGATCGGATCGTCCGGATTCGGATCCAGGATCCTCGCCTGCCTGGCGCGAAATACACGGGTTTTCGAGTCACCCGGGTCATAGATCAGCACATCGTGGAGCCGGCCATCAGTCCGGTCAATGCGTTCTGCCAGGATCATCCTGCCGTTTTCATTGTTCAGGTTGAACCGTTGTGCCTGCAGATGATTGACGTCCAGGTCTGTTCGCGATTGCTGTTCCAGCACATAGGCCTGCGTATAAGCCCAGGGGCGCCCGTAGAGCGAAAGCATGGCCACCGCCAGCGAGATCGGAATGGCCAGCAACAGGACGGCCCGATAGATCCGCAGCGGGCTTGCACCCGAAGCGGCTATCGCAATGATTTCAGAATCATGGCACAGGCGTCCCACCGCCAGGGTCACCGAGGCATACAACGCCACCGGCACTAGCATTTCGAGGGCAATCAGTACCTTGTAGAACACCATCTCCAGTACCGCTTGCAAGGCGAGAGTGCCCTCGACGGCGTCAGCGAGATACCGCTCTACCGAATAACTGGCAAAGATGAACACCAGGATGCTGACCATCACGATCACCGGCCGCCGGATCTCGGCGATCACGTAGCGTTCGATCAGGAACATGCCCTGGATCCCGGCCGGTCGCCTTGCCCATGCCGCGCTGGGGCGATTGAGCATTCCTGCCGCCAGGATCCATCAGGTATCGCTCGGTATCGATTGATTTCTCTGGGCATGAATTCTCTCCACCATTTGATAATCCAGCGGCGAATCGACATCGATAGCGGCCTCCGGGAAGGGCATGACCACCGCCCCGAGACTCACCCCCAACCGGTTGGAAAGCTGTTGCAGCGCTTGTTCCAGGGTCAATCGACCCAACAAATATCGCAGTACTCCCTCGACGCCCAGAGCGCCGGCGATCACCCGCCTGGGATGCTTGCGATCGTGTTCGACCCGTTGCCAGTAGCTGGCGAGACGTCGCGCGTCCTCGGTCATGAAGGCGAACAGGTTGCTGCCGCAATAAGGACCGCCGCGAAGCCGGATGCTGGTGCGCCGGGTTCCTGGAAAACCCGCCAGCACCGTGTCCAGCGGCGTTACCGCCACCACAAAGTCATGGCCGCCTGAAGTCGCCTGCGCAAGGAAATAGTCGACGATCTGCGGACTGAGCAGCGCATGATCCGCCGTGGTCACCAACACGGGACTGTCTGCGGGTTGACGCGCCAGCGCCAGCGCCGCGCTGGCGCTGGGGGAGTTGGCAGGTTCCAGCCAACTGACGCTGGCGCAGTCCAGCAGTTGCGCCAACGAGGCATCTTGCGCCATTAAATTTCGCGCAGGCCCCACGAGTACGATCCGGTCGATCCGGTCACTGGCCGCCAGCGCCTCGACGACTCGACGAACCATGGGAACCCCCGCCACCGGCGCCAATGCCTTGCAGCAAGTCCCGGCCACGGCAGCAACGGGGTCGGCCGGCCCCCGGTCAGCAGCCAGGACCAGCGCGGTGAACGGCCTGACCTCAAATGTGCTTTTCATAGATCCGGTAGCGCTTGTAGGCGGTGGCGCCGATTTGTTCGAGAATCTTGCGCATCACCGCATTCGATTCCAGGATCCACGACATTTCCAGGGCTTCTATGCCGCGCTTGACGAAGGGCGGCTTGAGCGCTTCGATCAACAGCAGGGCGAGTGCAGGCCCCAATCGGCTGAACTGGTAAGCCTGCTTGACGCCCATCAGGGGCACGCGTGCAGTCCGCGCGCCTTTGACGTAAAGCCGCCACAGCAGGCGTATCCAGCCAAAGGGCAGCAAGCGCCCGTCGAGCGAGGCGATCGCCTCGTTGATGTTAGGCATGGCCACGATAAACGCGCAGGGCTCGCCATCGACTTCGGCGATGTACAGCAAGTCCTTGGGGACCAGCAGCCTCAATTGGCTGCCAAGCTCGTAGAATTCGGATTCGGTGAAGGGGACGAAACCCCAGTTGCGGCTCCAGGCGTCATTGAAGATTTCCCGCAGGATGCGCATGTCCCGCCGGAACTGACGCGGGTCCAGCGGCCTGATCACCACGCGCTTTCGCTCGCGCGCCATCATCGCAGACAACGCTGGCGGGAAATGCAATTGATCGGTGCGCATCCAGTAGGCGAGCAAATCCTTGGCTTGCCGGTAGCCAAGGGCGGCGAGCCTTTGGTCATAAAAACGCTGTCCGTGGCCCATCATGGCGGAAGGGGGATGATCGAATCCCTCTACCAGCAAGCCGCTTTCCTGGTTGATGGTCAGGTTGAAGGGGCCCGTGATGCGTGCAGCGCCATGTTCGCGCAGCCAGGCTTCTGCCGCTGCGAACAGGCTGTCGAATACAGCGGGATCGTCCACGGCTTCCAGCATTCCGAAGTGCCCTGAATCATGGCCGTGTAATTGCCGGTGAAGGCTGTCGATCTGTGCGGTGATCCGCCCCACCACTTCAGTTCCCGACCAGGCCAGCCACGCCTGCCACGTCAGGTGAGGGGAGGCTGGATTCTTTTGCGAAAGGAGTTCATGGCGCTCGTAATGAATCGGTTCGATCCAGCAAGGATCGTTGCGATACAGGGTGCCGGGGAAACTGATGAATGTCTTGAGGTCCAGGCTTGTGAGGACGGGTCGCGTAATGATTGGCAACTTCTTATTGATCATCGTTGGCCACAAAAGTCCGAAGCAGTTGAACTCGTATCCCTTTCTTAGTACCTCAGAGAGCGTAGCTGAAGTATTGGCGTAGGGCGTACGTGCAGAAAACAAGGGTGCCAGTGATCCAGTAAAAGCTCGGTAATCCGTGTAATGCTGTTCACTTTAGGTTTGGGGGTTGCAGGTGCATGTTTGGATTGGGTGTATATCCGTTGTTGCGGTAACGCCTACTTAGGGTTTCGCTTTTACTGTTGGAGCCAGGCTTGCCGGCGAAGGCGTGCTGGCAGACGATAATTGTCTTTCAGGTGTACATATCCGTTGCTGCGGTAACGACCACCTAGGGTTTCGCTTTTACCTGTAGGAGCCAGGCTTGCCGGCGATGGCGTCCTGGCGGCCAATGGGGATTTGTGACTGAGTACATATCCATTGCTGCGGTAACGGCCGCCTATGGTTTCGCTCTTACAGCGAGTCACTTGGAAGAGCCCCAAGTAACCAAGGGCTCTTGCCCCTGGCGTTCGGTGCCTCGCTAAGGCTCGGCATGCCCTCGCTCCGGTCCTGCTCCGTGGGTCGCCGCGATGGGCCATCCCTGGCCCAGCGCGGCTAAACCGGCATCCTTGCCGGTTTACCCACTGCGCAGAACCTCCACTCGGCCTCTCGAGGGGGCAAGAACATCAAAAGCCAGATCACAATCAAAAGCGAGGCGGCCGACCGGCCGGCCTGATCGGAAGCCATGCGCGTACCTTCTGTAGGAGCGAGCATGCTCGCGAAAAACCTGAGAGCACCGCGGGCTGACAGTTGCCCAGCGTTATCGTTAACGACCATCGTCGGAACGCCGCCCGGAGCATGCTCGCTCCTACATGGGGATCCAGGTTCACCCGTAACAGTCAGGTCGGCTTTAAGGCCGCCTCGCTTTGCTGTTGATCGCGGGCGCCCCGTTAACCACGATGGCCGAACGCAGGCATTGCGCAGTGGGTAAACCGGCAGGACGCCGGTTTAGCCGCGCAGGGCCATGGATGGCCCTTCGCGGCGACCCACGGAGCAATGCCGGAGTGAGGGCATGCCGAGCCCAAGCGAGGCACCGAGTGGTGGGGCAAAGCCTTTTGCTTCCTTTTTGGCGTTTGAAAAAGGGAGTCGCCGTAAGGGCGAAACCATAGGTGGCCGTTACCGCAGCAATGGATATGTACGCAGGCAACCAATTTCACACAGGGCTTCTTGTGACGCCCACCGCATCAACGTTGCGCACGGCTCATGTCATGCGTCGTCAGTGGAACGCGGAGCGTCCCTGGCGGCATTCCCACGCAGAGCGTGGGAACGATCAATCAATGTGCTGCCGCCTTCGCGAGCAGGCTCGCTCCTACAGGGGATTCAGGTGCACCCGTCAAAGTCAGGTCGGCTTTAAGGCCGCCTCGCGTTGCTGTTGATCGCGAGCGCCCCGTTAACCACGATGGCCGAACGCAGGCATTGCGCAGTGGGTAAACCGGCAGGACGCCGGTTTAGCCGCGCAGGGCCATGGATGGCCCTTCGCGGCGACCCACGGAGCAATGCCGGAGTGAGGGCATGCCGAGCCCAAGCGAGGCACCGAGTGGTGGGGCAAAGCCTTTTGCTTCCTTTTTGCTGGGCCGGCACTCCGGCGTTTGAAAAAGGGAGTCGCTGTAAAAGCGAAACCATAAGCCGCCGTTACCGCGGCAATGGATATGCACTCCGACAACCAATTTCACACAGGGCTTCTTGTGACGCCCCCGCATCAACGTTGCGCACGACTCAATTAATGCGTTGTCAGTGGAACGCGGAGCGTCCCTGGCGGCATTCACACGCAGAGCGTGGGAACGATCAATCGCCAGTAGGGGATCAAGGTACACCTGTCAAAGTCAGGTCGGCTTTAAGGCCGCCTCGCTTTGCTTTTGATCGCGGGCGCCCCGTTAACCACGATGGCCGAACGCCGGTTTAGCCGCGCTGGGCCAGGGACGGCCCATCGCGGCGACCCACGGAGCAATGCCGGAGAGAGGGCATGCCGAGCCCAAGCGAGGCACCGAGTGGTGGGGCAAAAGCCTTTTGCTTCCTTTTTGCTGGGCCGGCACTCCGGCGTTTGAAAAAGGGAGTCGCTGTAAAAGCGAAACCATAAGCCGTCGTTACCGCAGCAATGGATATACACCCCGTCCAATTCTTATCTACAACCCCACGCTTAAGTGAGCTGTATTACAGTAATCAGCGCACTTTGTGATAAACATCACGCTTGAGAACGAGAAGCTTTCATCGCGATTATTACTCGCCGGTCGTCGCTCATCCGGGAAAAAATTTGCGCTCATCCAGATGCCGATTAGTATTGCGTTAGGCTCTGTAAATAATTGAAAAGGCTGAGCCGGATATCCTTGGGGCCACGACTCCATGGAATCGGTTTTGAGGGCAGTAGAACGGCACGTGTTTTACTGGCGCAGGTGATAAATACGCTATTTGACTTGTCCTTACTTGGCTAAATGGATGGGTGTCTTCTTATGTCTGCGACCTTTTCAAACCAGGCACTTACCCAACGTCTAGCGGACTTTCCCACGCTGGTGGAAGCACTCGATTATGCCGCTTCAGGCCTGGGCGGGATGAACTTCTACGACAGACATTGCCGCTTGAATGCAGCGCTCGAATACTCAACGCTCAGAAGTAATGCTGTCTCGATTGCCCAGCGCCTACTTGGGCTCAAGTTGAACAAAGGCGATCGGGTTGCGCTCATCGCCGATACGCACCCAAGCTTTATCGAGTCGTTTTTCGCCTGCCAGTACGCTGGCTTGATCGCCGTTCCTCTGCTGGTTCCTGCCAGCCTGGGAAGCCATCGTTCCTATGTGGACAAGTTGAAGGGGCTGTTCGCCAATTGCACGCCGGCGGCCGTTTTGGGGGTGGAGGAATGGCTGCCCTATATCCGCGAAGCACTGGGGGACACCCGGCAGGTGTTCGTCGGGACGCTTGAGGCATTGGGCGAATTGCCCGCGTTGCAGACGTTACCCACGGTCGTGCCGGAGGACATCGCCTACCTGCAATACACTTCCGGCAGTACCCGCTTCCCGCGTGGCGTGATCATTACCCAGCGTGCGGTGATGGCCAACATCAGAGGCATCGTCGTGGACGGTGTTGGCGTTCGCGCAGGGGATCGGTGCGCCTCATGGTTGCCCTTTTATCATGACATGGGGCTGGTGGGTTTTGTCTTGGCGCCCATGGCGGCGCAATTGACTGTCGACTACTTGCACACCCGGGATTTCGCCACTCGGCCCGGGCAATGGCTCAAGCTTATCAGCCAGAATCGAGCCACTGTCTCGGTGGCGCCGCCCTTTGGCTATGACCTTTGTACCCGGCGAGTCCGGGACCTGGAAAAAACGCCGCTGGATCTCTCCTGCTGGCGCGTGGCGGGGATCGGGGCAGAACCGATTCGGGCATCGGTGTTAAGCCGTTTCGCCGAGTGTTTTCTCGACACCGGATTCGATCCGGCTGCCTTCACGCCTTGCTACGGTCTGGCGGAAAGCACGCTGGCCGTCAGCTTCGCCCGTCGCGGGGTGGGGGTGCAGGTGGACCATGTCGCGCGCTCGGTATTGGAGCATCAGCTCAGGGCGCAGGCGAGCGCCGCCGATGATCCGGCAAGCTGCGCTTTCACCAACTGTGGCGCCCCTTTGCCCGGCCATCGCGTGGAAATCCGCAACGCTGCGGGGCGGCAGGTTGCGGAGCGTGAGGTAGGGCAGATATTCGTCCAGGGACCCAGCGTAATGTCAGGTTATTTCAATGACCCACAGAGCACCTGGGCAGTCCTGGAAGATGGCTGGCTGAACACCGGTGACCTGGGCTACCTGTCCCAGGGTGAACTGCATATCACCGGTCGGAGCAAGGATTTGCTGATTGTGCGCGGTCGCAACATCTGGCCGCAGGATATTGAATACCTGGTGGAATCCGAACCTGAACTGAGGCCCGGCGATGCGATTGTGTTCGTCGTTCCCGTCGATGATGAGACCCAGGTCGTAGTCCAGATTCAATGCCGCATCCGTGAGCCAGAAGGTCGTGAACGCCTGGTCCGTACCCTGGTGGCGAAGATCACCAGTGAGTTCGGTCTCACTGCTGACGTGCACCTTGTGCCTCCTCACTCGTTGCCGCGAACCTCCTCGGGCAAGCCTTCCCGTGCCGAAGCCCTTGAACGATTTTTGGCCCAGGCGAACACCGACCTTCCTTATCCAGCGCTGGAGGTGACGTGAGTGCTCGCGTTGTTTCGCTCACTGGCGCGACTGGCTTCATAGGCAGTGTCCTACGCGAACGGCTCATCACCCGTGGCGTGGAGGTCCGTGCCCTGGCTCGCTCCAGGAGCGCAATGACAGCGGATGGAACAAAGTGGATCATCGGAACACTGGAAGATGAACAGGCCCTGGCCGAGCTCACCAGGGGGGCAGATACAGTCATTCATTGCGCAGGGAAGGTCAGGGGCAGGAATGCCCGAGACTTCGACGAGGTCAATGTGCAGGGCAGCAAGCGCTTGATGGAGGCGGCGCGAATGAGTGGGAGTTGCGAGCGTTTTTTGCTGATCTCGTCCCTTGCCGCTCGCTATCCGACATTGTCCTGGTACGCCGCTTCCAAATTCGAAGGGGAATGCCAGGTCAGGGAGGCGGCCGGGACGATACCCGTGTGCATTTTCAGGCCAACCGCCGTATATGGACCAGGCGACCGCGAGTTGCGCCCGGTGTTCGAGTGGCTCCTGCGGGGCTGGCTGGTCACGCCCGGTAAAGGCGATTCACTGCTTAGCTTTCTGCATGTCGACGATCTGGTCAGTGCCGTCATGCAGTGGTTGGATGCGCCTGTCATGCAATCGCAGACCTTTGAATTATGTGATGGCCAGGCGCAAGGGTACGACTGGGCAAGCCTGGCCAGCATCGCCACCGATATCCGCAATGCGCCGGTACGGCAAGCGGTAGTGCCTGCCAAGGTGTTGAAGGGGATCGCACGAGCGAACCTGGTGCTGTCGCGCTTCACCCGCCAGGCGCCCATGCTGACCCCCGGTAAAGTCAATGAGCTGATGCACCCTGACTGGACTTGCAGCAATGCCCGCATCAGCGCGGTATTGGGTTGGGAGCCGCAGATTCTGTTAGGGCAAGCATTGCGCAATCATCTGTACTGAGCGGCGAAGAACGACTGAACCCCAGGAGATCCACGATGATCACAGAAGAAGCGATACTCAAAAAAGTCATGGAGATCATCGAGCCGTTTGCACCATCTGGAATGGTAATCAAACCGAATTCCGATCTGACCGGAGACTTGGGGATGGAGTCGATAAAGGTGATGGACATGCTGTGGGTATTGGAGGACGAGCTCAAAATGTCGATCCCTCTCAATATCCTGATGGACGTGCACACTCCCGACCAGTTGGCTCATGCCATTCTTACCCTGACGGAGCGTAAAAATGGGACTGTTTGACAAGTTCGGCAAGCTGGCAGCTGAGCGCGCCAGTCTCTGTGGCACACAGATCCATCCTTTTGGAATTCGCATCGATGAGATGTATTCCCCCACCGAGGGCTGTATTGAGGGGCAAAGGGTCATTCTCGCCGGCACCAATAATTATCTTGGACTCACCTTCGACCCCGCCAGCATCAAGGCGGCGCAGCGCTCACTGGCGCTAGAAGGCACCGGCACTACCGGTTCTCGCATGGCCAACGGCAGTTACGCCGGACACAGCGCGCTGGAAGAGGAACTGGTTGATTTCCTGGGGCGAAGTTCCGTCATCGTGTTCTCGACAGGCTATGTCGCCAACCTGGCTGTCATCGGGACGTTGGCAGGGTCGCGCGAGGTCGTGTTGCTTGACGCTGACTGCCACGCGAGCATCTACGACGCTTGCAAGCTGGGAGGCGCGGAGATCATCCGTTTTCGCCATAACGATGTCGCTGATCTGGAGCGGCGCATGGTCCGGCTCGGCGAACGCGCGCGGGAAGCGATTATCCTGGTGGAAGGGATCTACAGCATGCTGGGCGACCAGGCTCCGCTCAGAGAAATAGTCGAGGTCAAGCGCCGCCTTGGAGGTTACCTGTTGGTTGACGAGGCGCATTCCTTTGGCGTCCTGGGGGCCAACGGGCGAGGCCTGGCCGAGGAGCTGGGTGTGGACTCGGAGGTGGACATCCTGTTGGGAACGTTCAGCAAGAGTCTGGGCGCCGTCGGCGGATTCGCCGCCTGTCACGACGCGCAAATGGACCTGCTTCGCTACGCCAGCAGACCTTATATTTTTACCGCTTCACCAGCCCCCTCGGCGATTGCCTCGGTAAGGACGGCGCTGGCGGCCATCAAGGAACGCCCGGAGCTGCGGCATCAGCTGTGGTCGAACGCCCGACGGCTGTATCAAGGTTTGGCAGAGTCAGGCTACCAGTTGGGACCGCAGGCCAGTCCAGTGATTGCCGTCATGCTGGAGTCGCCTCAAGAGGGCCTGACCGTTTGGCGGGCGCTGATAGAGAGGGGCGTCTATGTCAATCTGGTCCTTCCTCCCGCGACCCCCGGCGCCGTCACCCTGGTGCGTTGCAGCGTCAGTGCGGCCCATACACCTGAACAAATTGACCGGATCATCGAGGCCTTCGCTTCATTGCGTGGCGCGATGGGCCAGGTCACGGCGGGCGCTTGATGAGTGTCGTGAGCTGTCGGTGAGCTAATCTTTACCTACGTCATAGTGAACCACAGTCATGCGGATTATTTTTGCCTTTGGCCGCTCCTACCCGGCCCGCACCGTGCTGATGCTCCTGAGCCTGCTGCTGGCAGGGGTGGTTGAAAGCGTCAGTTTGAGCACGATGCTGCCCTTGATATCGGCCATGCTTGAAGACCAGCCTCATTCGAAGCTGGCGGTCTACGTCTTCGGGGCAATGAACTCGATCGGCCTGCAGCCGACGATCGCGAACATGCTGGTGGTCATTGTCGTGGGCATGACGCTGAGCAACCTGCTGATATTGTTGGGCAACCGTCAAGTGGGCTATACCGTGGCACACGTGGCAACCGACCTGCGTGTGAGCCTCATCAAGGCATTGCTGGGTAGCCGCTGGGAATATTACCTGCGCCAACCCTCCGGAGCACTGGCCAATGCCGTTGCAACCGAAGCCTTCCGTGCTTCCACGGCTTATGAGCATGCGGCCAATATGCTGGCGCTGGGTATCCAGGCGGCGGCCTATGCACTAATCGCGCTTTTTGTCTCGTGGCAGGCCGCGATCCTGTCACTGGTGATCGGCTTCGTCCTGCTGGCTGCCGTGCGAGGTCTGGTCAAGACATCGCGGCGTGTCGGGAAAAGCCAGACCCGCCTGATGCGCGAGTTGCTGGTCCACCTGACGGACACCCTTGGCTCGGTGAAACCGCTCAAAGCCATGGCACGCGATGACATCGCCGATTCCTTGCTGCGTCGTCACGCCGGCGAACTCAATACCGCATTGGAACGCGAAGTGATGAGCCGCGAAACGCTGAGGGCCTTGCAGGAGCCCATGCTGGCGATCCTTGCCGCGGCGGGCCTCTACGCGGGGCTGGTCATCGGCGGCATGCCGCTGTCTTCGGTGATGGTGTTGATCTTCGTGGTAGTGCGCATGCTGGGGTTGCTGCACAAGGCACAGCAGCGCTATCACCGGATGGCCGCGCAAGAGAGCGCCTATTGGGCCATTAACGAGTCGATCGACAACGCTATTGCCGATGCCGAGCCTGTCGGAGGGACTTGCACGCCTTCCTTGCAGCGGCATATCGCTTTTGAAAATATCAGTTTTGGCTACGGCGGGCGGCAGGTTCTTAACAACGTGTCGATGAATTTCCCGGTCGGTTCATTCACCACCATGATCGGTCCGTCCGGCTCCGGCAAGACCACCGTGCTCGACCTGATCTGTGCGCTGCTCGCGCCACAGTCCGGACGCATCAGGGTCGACGACTGTGACTTGCATGCCCTGGACAGGAAGGCCTGGCGCCGAATGATCGGCTACGTCACCCAGGAAACCCTACTGCTGCACGATAGCATCCTGGCGAACGTCACCTTGGGAGACAGGGCCTTGAACGCCGCCGACGCAGAGCGCGCGCTGCGTCAGGCCGGTGCATGGCAGTTTGTGCAGGAATGCCCTGGCGGACTGCAATCGATCGTCGGCGAGCGCGGGGCCAAACTCTCAGGAGGGCAAAGGCAGCGTATCGTCATCGCGCGTGCCCTGGCCCATCGCCCCAGGCTGCTGATCCTGGACGAAGCCACCAGCGCCCTCGATCCCGAGTCGGAGGCCGAAATATGCCAGGTGCTGAAGAATCTCACGCCTGGCATCACGGTCATCGCAGTGTCGCACAGGCCTGCCGTGATCCGCATTGCGGATCAGATTCTCGAGGTCCGAGACGGCAAGGTACTGGCCACGCACCATGCCGTCGATCCTGATGGCACTCGGGCTGACGAGGCGAAAGCCTGAGAAAAGCGCAGGGGTAGGGGGCGTCCGGTCTGTAGGAGCGAGCATGCTCGCGAAAAACCTGAGAGCACCGCGGCGTGTCAGGCTCCTCGCAACATCGTTGACCTCCATCGTCGGAACGCCGCCCGGAGCATGCTCGCTCCTACAGAGATATCCGTTCATTCGCGGGAGCTAGCGTTTACAGGCTGCCGACCAGATGGCCGCCGTCCACTGCCAGGACCGCGCCTGTCATGAAGGCGCCGGCCTCGCTCGCGAGCAGGAGAAACGGGCCTTCCAGTTCCTGCAGGCTTCCCAGTCGTCGCATTGGCACGGTGTCGCGTATATACGCCTGGCCCTTTTCGCTGTCGAAATACTCATCGTTCATTTCGGTCTTGAAGTAACCCGGCGCAATGGCATTCACGCGGATCTGGTAGCGCGCCAGTTCCAGCGCCAGGGATTTGCTCAGTTGCACCACGCCAGCCTTCGCCGCGCAGTAGTGGCTGTAGCCAGTGCCTACGCGCAGCCCGAGCATCGAGGCGATGTTGACGATGCTGCCAGGTCGCTGTGCCTTTGCGAGGCGTTGCGCTGCACACTGGGCAACGCGCCAGACGCCGTCGAGGTTGGTCGACAGCATCGCCCGCCAATCGGCCTCGCTGATCTCCAGCACGCGCTGGCCGTTGCCGATGCCGGCATTGTTGAGCACTACATCCACCACACCGAAAGCAGCCTGGGCGGCGTCAAACGCTGCTTCGACGCTGTCGCGATCGGTAACGTCCAGGGCCACGGCCATAGCCTCACCGCCAGTCTGGCGAATTTCGTCTGCCAGTTGCTGCAAGCGCTCCACGCGCCGGGCGCCTAGCACTACGCGCGCACCCGCATCGCTGGCCACGCGCGCCAGATGCGCGCCAATGCCGCTGGAGGCACCGGTGACCAGTACCGTCTTGCCAATCAGGGAAAAACCGGGGTTTTCATTCATCGCATTGTTCCTGTCGGGGAGTGGATCGGCCGCCCATGGCGGCCGATCGGGACTCAGATTCGTTCGATGCGGGTCTTGCCGGCAGCCACCAGGTGTTCCAGCAACGGGGCAGGGTGGAACCACATCTCGCCGTATTCGCCGAGGGCCTTGCGGTAATGGCGGATACCGTCCAGCACCTTGTCCAGGCCGATCTGCTCGGCAGAATGCATCGGCCCGCCGAGCCACGCCGGGAAGCCGTAACCGTTGATCCACACCAGGTCGATATCGCCACTGCGCTCGGCAATGCCTTCGTCGAGCAGCTGGATGCCCTCGTTGATCAGCATGAACAGGCAGCGGTCATGAATCTCCTGCGTGGCGATCGGCCGGCGGCGGATGTCCAGTTCGCCGGCGATGCGTTCGGCCAGGGTGATGACCTCGAAGTCCTCCTTGCGCTCGCGACCCTCATAGATATACGCACCGCGCCGGGTCTTCTGGCCGAAGCGGCCGAGGGCGTTCAGTTCGTCAGCCAGGCGGCAATAGCTCGGATCATGGGCAATCGCTTCACGACGCGACTCGCGCACCAGGAAGCTGACGTCGATCCCGGCCAGGTCGTGCATCGCCATCACCCCCATGGCCAGGCCGAGGTCAGTCAGCACCTGGTCGATTTGCGCTGGCGTAGCGCCCTCCAATACCAGGCGATGGGCTTCGCGGGAGTAGGGTTCGAGCATGCGATTGCCGATGAAGCCGAAGCACACGCCGGACACTACCGGGATTTTTCCAATCGTCTTGCCCAGTTTCAGTGTGGTCGCCAGCACCTCGGGCGCGGTGAGTTTGCCGCGAACCACTTCGAGCAGGCGCATCACATTGGCCGGACTGAAAAAGTGCAGGCCGATGACGTCTTGCGGGCGGCGCGTAACCGCGGCGATCTGGTCGACATCGAGGGTGGAGGTGTTGCTGGCCAGAATCGCGCCTGGCTTGCACACCTCATCCAGGGTGCGGAACACCTGTTGCTTGATCGGCAGGCTTTCGAACACCGCCTCGATCACCAGGTCGCACTCGGCAATGTCGGCATAGTCAAGGGTGCCGGTGAGCAAGGCCATGCGCTGGTCGAGCTGTTCCTGGGTCAGCTTGCCGCGTTGCCGGCTGATCTCATAGCTGCTGCGGATTTGCCCCAGCCCACGCTCCAGCGCCTCGGGTTTGAGCTCCAGCAGCGTGACGGGGATGCCCACGTTGGCGAAGTTCATGGCGATGCCACCGCCCATGGTCCCGGCGCCGATCACCGCGACCCGGGCGACCGGACGCAAGGCAGTGTTAGCGGTGACACCGGCCACTTTGCCGGCCTCGCGCTCGGCGAAAAACACATGGCGCAAGGCCTGGGATTGCGTCGAGGCTTCGGCTTCCTTGAACAGGGCGACTTCGCGCTGCAGGCCGGCCTGCAACGGCAGCACGCAGGCCGACTCGACGGCCGCCAGCAACAGTCGGGGCGCCAGGCGGTTTTTCCAGCGCGGTTCGTGGCTGGCCCGATAGTCTGTGAAATACCCTTCGGGCAGGGCGGCGGCCGGGTTGGCGTGACGTTCTGCGGGGCGTGCCGGTGCGCTTTCGCGGATCAACTCCTGGGCGAAGTGACGTGCGCCATCGAGCAGGCATTCGCCGTCCCCGGGCAAGCGGTCGATCAAGCCGAGCTCAAGGGCCCTGCCTGCGCTGACAGGCTGGCCGGAGATCATCATTTCCAGTGCCGGTTCGGCACCGATCAGTCGCGGCAAACGTTGGGTCCCGCCCGCACCGGGCAATAGGCCCAGATTGATTTCCGGCAGGCCGAGGCGGCTGTCGGCAGCGCTGATGCGGTAACCGCAGGCCAGCGCCAGCTCCAGCCCGCCACCGAGGGCGAAGCGATCGATGCTGGCAATCAGTGGTTTGTCGATTTGGGTCAGACGCAACAGCAAGTCGGGCAGCGAAGGGGCGGCGAAAGACCCGGGAAGGCCGAATTCGCTGATATCGGCACCGGCGCAGAACAAGCCGTTTGCACCGTGCACGATGATCGCCGAGACGGCAGGATCGCTGGCGGCGCGCTCACAGGCGTCGAGAATGGCCGCACGCAGGGGTTGCCCCAGTGCGTTGACCGGCTTTGATGCCAGGCCGATCAGGGCGAGGTTGTCTTCGACGTGGTAGGTGACCAGGTTGCTCATGTTGATTTCCCGAAATTTATTGTTATCACGGCCCCCTGTAGGAGCGAGCATGCTCCGGGCGGCGTTCCGACGATGAACTTCCAAACACCGCGTGAATCCTGAAAGCACGCGTTATCGTTGACGACCATCGTCGGAACGCCGCCCGGAGCATGCTCGCTCCTACAGGGGAGGGGCATTAGAACCAGCGGTCCTGCATGTAGTAGGCGACATGGTTGGCTTCAGTGAGCAGCCGCCCCTGGGACTCCAGCGACGCCAGTTCCCAGGTCATGTAGTAATGCGCAGCCTGCAACTTGCCTTGATAGAAATCGGCGTCGCTGTCGCCGGCGCCCGAACCCAGGGCGCGGCTGGCCAGCAGGGCCTGGCGCAACCAGATCCACCCGACCACCACGCGTCCAAACAGGTCCAGATAGGGCGTGGCATTGGCCATGCCGAGGTTGGCATCGGCCGTCACCTGCGTTTGCAGGCTGGCGGTGACTTGCTCGAGTACGCGCAAGGCATCGGCCAGCAGTGCCGCGAGCGGCGCACAGTGTGGGTCGCTGTTGGCGGTGAGCAGGGTGGCAAGCACTTCGGCGGTGAACAGTCGATAGCCATCACCTCCGCGCGGCCCCAGTTTTCGACCCAGCAGGTCGATGGCCTGGATGCCTTCGGTGCCTTCATGAATCGGGTTCAGGCGATTGTCGCGGTAGTACTGTTCCAGCGGGTATTCGCGGGTATAACCGGCGCCGCCAAGCACCTGGACGCCAATCTCGGACGCGAGCAGGCCGTAGCGCGAGGGGTAGGTCTTGACCACCGGCGTCAGCAGGTCGAGCAATTCGCCGGCATTGTTGCGCGCCAGCGCAGTGGTCGCGGTGTGGGCATCTTCCACCAGGCTGCTGGCATACAAGCACAGCGCCAGGCTGCCCTCGGCGTAGACCTTCTGTTGCAGCAGCATCCGGCGCACGTCGGCGTGCTCGACGATGCGCACCTGGGGTGCCGCCGGGTTCTTGTTCCCGGGCAAGCGGCCCTGTGGCCGCTGGCGGGCGTAGTCCAGGGCGTGAATGTAGCTCTGGTAGGCGAGGCTGGCGGCCCCGAGGCCGACACCGATGCGGGCCTCGTTCATCATCTGGAACATGTAGCTCAGGCCCTGATGTTCCTCACCGACCAGGTAGCCCACGGCGCCGTCGTGCTCGCCGAAGCTGAGCACCGTGGACGTGGTGTTGCGATAGCCCATCTTGTGCAGCAGGCCGGCCAGCGCCACGTCGTTGCGCGCACCGACGCTGCCATCGGCATTGACCAGGAACTTGGGCACCAGGAACAGCGAAATGCCCTTGGTCCCGGCCGGCGCGCCTTCGATGCGGGCCAACACCATGTGCACGATGTTCTCGGTCAGTTCGTGGTCGCCACCGGAGATGAACATCTTCTGGCCGAAGATCCGGTAAGTGCCGTTTTCAGCCGGGCGTGCCAGGGTGCGCAGGTCGCCCAGCGCCGAGCCCTGGCCGGGTTCGGTGAGGGCCATCGTGCCGCTGAAGCGACCGTCGAGCATCGGCGCCAGGAAGCGTTCAAGCAACGGTGGACTGGCAAAGGCCCTGAGCAGATTGGTCGCGCCGATGCTCAGGAAGGAATAGGCGACCGTGGAAATATTCGCCGCGTTGAAGTAGGCCATGCAAGCTCGCAGGATCACTTCCGGCAATTGCAGGCCGCCATCGGCAAAGTCGTGGTGGGCGGCCAGGAACCCGGCCTGGGCAAAGGCGTCCCAGGCGACTTTGGTTTCGGCGATCATGTGAACCCGCTCGCCATCGAAGGTCGGTTCGTTGGCATCGCCCTTGTGATTGTGCGGGGCGAACAGCTCAGCGGCGATCTGGCGGGCGGTGGTGAGAGAAGCGTCGAACACGCCGCGGTCGTGCTCGGCGTAGCGCGGGCGTTGCAGCAACGCTTCGGTATCGAGCAGCTCGTAAAGCTGGAAGCGCAGTTCGCGTTCGTTGAGCAGCAGGTCAGTCATGGCATCTCTCGTCAAACAGTGTCGAGTGTGGGCCATGGAAGCAATTCTCGGCCCGTTACAGGCGTCCACAATAGTGTGATGTGCCGGGCTTTTATCCCCCTCCTTTGGGGGAGGCCCGGACGTCGTCAGGTGACGGAAACAGTGTCCTCGCCCGCAACAGGCGCGAAGAGAGAGCCTCGAAGGTTCCAGGCACGGGGCTTGCGTCGAAGCACCCACCGCCGATGCTATGATCTGAGCGTCTAGGCCTGGCCAAGAGATCGTCCATGGATCGCCTGTCTACCTTGTTTTCGCAGTTCGGCGTACGCGCAAACCTGTTTTACAACGGCAGGTTATGCGGCCTCGCGTCCTACGATGGTGCGCAAGGGCGTGGTTATGTTCATCTGCTGCAGGCGGGCAGCGTCACGTTGCTGGGCGCCGATCGCAAGGACTTACTGCTGACCCGGCCCAGCCTGATTTTCATGCCACGCCCCAGCCGACATCAGTTGTTTGCCAACGAGTCCGAGGGCGCTCAACTGTTGTGTGCCTCAATGGAGTTCGAGGGCGGAATCGATAATCCGTTGGCGGCTTCGTTACCCGATTGCCTGGTGTTGTCCCTGGATGAACTGCCCATGCTGGCCGATACGCTGAAGTGGATGTTCGGCGAGGCAGCGAGCGCGCATTGTGGCAGGGAGGCAGCTCTGGAGCGTTTATTTGAACTGCTGATCATCCTGTTGTTTCGGCATCTGCTTGATCACCAACAATTGCGCACCGGAATGATGGCCGGCCTGGCTGATCCGCGGTTGGCTCGCTCCCTGGTGCAAATTCACAACGCACCCGAGCGTGCCTGGTCAATTGCGCAACTGGCGAGCGAGTCGAATATGTCGCGCGCGGCCTACGCGGTGCATTTTCGCGACGTCATCGGGCAGACACCTGCCGAATATCTGTTGAGTTGGCGGATCAGCCTGGCGCAGAAACGCCTGCGTGAAGGGCGGTCGATTACGCTGATCGCCGCCGAGGTCGGCTATGAAAGCCCTTCGGCACTGGCACGTGCGTTTCGACGCAAGACGGGCTGCAGCCCGCGGGACTGGGTGAAAGACCTGGCGGGAGACGATGATGGGGCAATGGCCTGAAAGCATCGAACTGCTTCAGGCCATCGCGCAGGGTCGATCATCGGTTCAACGGCTTTGCAGCTAAGTCAGGGAGTGGCCGGCGATAAATATCGAGGCGGCAAGCAAGCCGATGTCCTTGAGCAGAAACTGCCCCGGCGCCACCGAGATGCCTGGAAAACCGAGGCCGGGTTCAATCACGCCGGGGGTCGAAAACATGAAGCTCAAGGTGGTGAAGAACAGTCCGGCAGACAGGGCTGCGCCGATCAATGAAAGCTTGGGTGACAGCAAGCGACCTGCAATCAGGACCCCGATCGAGACCTCCAGTATGCCAAGCAGGCTGGAGAAGGTATCGACACTGAAAATGTCGTAGACCCAACCCAGCAGAGGGCTGTTGCTCACCAACGGAACCAGCCCGACGGCTTCGTAGTGGGTGAACTTCATCCCGCCAAACCAGAAGTAAATGACGGCGAGTGCAAAGTAGGCACCGTAGGTGCCAAGCGCCATGGTTTTGATCCCGAGCGTGGAAGAGCTTTGTACGTTGGTGCTGCTGTTGTCGATGCTTAAGGTTTTCATGATCAAGGCTTCCAGGAGAGTGGTGAGGAACGCTAATCAACAACCCGGCGCGGTGTGCGTTGGGAGTGCGGACAGTGTTGCCTTGGATGCCATGCTCGTGGCGCCAGAACGTATTGCATTCAGTGCAGATCGTCTTGACTTGGCGACGAGAAAAACCACAAGACCAGAGCAGCAGCACTGATCGAGGCGCCCAGCAGGCTGACGGCCATCCAGCCCCAAAGCGCATAAACCTGGGTCGCTGCGGCGGCTCCCAGCGCGCTGCCGACCGAGTAGAAGCACATGTAGGCGCCGACCATGCGACTGTGCGCGTCGGGTCGTGCGGCGAAGATGATGCTCTGGTTGCCGACGTGTACTGCCTGCACCGCAAAGTCGAGCAGGACGACGCCGCAGACCAGGGCGACCAGGGACGTCTGGGCGAATGCAATGGGCAACCAGGACAGCGTCAGGAGCCCTAGCGAAATGCCGGTCACTCGTTGCCCCAGGCCTTGATCGGCCCAGCGACCGGCTCTTCTGGCCGCCAGGGCACCGGCGACGCCGGCCAGGCCAAACAGGCCGATAGCCGTGTGTGACAGCGACAGCGGCGGGGCGCTCAAGGGCAGCACCATGGACGTCCACAACACGGAAAAAGCGGCAAAGATCAGCATCGCCAACAGGCCTCTGGCGCGTAACGTGGGCTCGGTAATGAATAGGGTGAACAGCGAACGGATGAGCGTGAGGTAGCTGTCTTGATGCCTCGACACTGCCGTTACCGGCACGCTTTTCCACAGCACCGCCGCGAGCGTGAGCATCAGCCCTGAAGACACAAAGTACACGGCGCGCCAGCCCGCGATGTCCGCAATCACGCCAGAGGTAAACCGCGCCAGAAGAATGCCCAGGACAATCCCGCTGGTTACCGTCCCGACGGCTTGCCCGCGTTGCGAGGGCGTTGCGAGCGCGGCGGCGTATGCCACAAGTACCTGTACGACCACGGCCAGCAGGCCCATCACGATCATGGCACTCAACAGGGCCAGCCATTGCTGGGCAGCACCGACCGCCGCCAGCGCCAACGCCGACAGCAGCACTTGCGCCAGAATCAGCCGCTTGTGATTGACCAGATCCCCCAGCGGGACGATGAACAGCAGCCCCAGCGCGTAACCCACCTGGGTGGCCGTCACCACAATCCCGATCATAGATGAGTCCACGCCCAGACTCTGGGCCATGGAATCGAGTAACGGTTGCGCGAAGTAAACGTTGCCGACTGCAAGTGCGCAGGTGATGGAAAACAATAACGTCAGCGATGGTGAAAGCCCTGGAGAGTGTTCGAACCCGGTGCATTCGCCGATTTGCCCAGGCCGCCTGACCAGGCATTGGGCCGCTGAATCGGTATCTGCTGTCATGTGCGCCTCCGTGGCGTTAAACTGGTTGCAAATTAAAACCTGAATCTATTGTTGGCATGACAGGTTTCAAATTGCAACCACATTCCCGGGAGTAAAAAATGCTCGACGACGCTACGCCACAAGGCAACGAATGCCCGGTCGCAAGAACACTGGAAGCCATTGGCGATCGCTGGTCGCTCATGATCATCCGCGATGCCTTTGACGACATTCGCCGGTTCAGCGAATTTCAGAAGAGCCTGGGCGTGGCCAAGAATATTCTGGCTTCGCGACTGAAGACTCTGGTCGAGATCGGGATATTCGACATCCGACCGGCGTCGGATGGCAGCGCCTACAAGGAGTACGTGCTGACAGAGAAAGGACGGGAGATCTTTCCGTTGGTGGTCTGCATGAGGCAGTGGGGCGAACGATTCCTGTTCGAGCCGCAGGAGACCCGTTCTGTGCTGTTGGACAACGCGTCCGGCAAGCCGTTGATGCCGATTGAGGTGCGCTCAGCGAGCGGGCAGACGCTGCGGCCCGCTGATTGCCACAGGGTGAGACTGGTTGATGGCGAGTCGTGAATCGGCTGTTGTCATTCCAGAAGTGGTGAGGGCCAAGCAAACTTTCCATCATCGCCCAGGCTGCCATTGTGAGTACCCTGGCAGACCCTCCCCATTCAGCCACGCCACGTCCTGCTCCGTCCAGATGTGATATTCGGGCCTGGAACCAGGATCCTCGTCCAGCGTCGCCACGCGCACGATCATCGCGCTTGAGCCGTTACGCTCTGCCGCAAGGTGCGATCCGCAGTGCGAGCAGAAGTGTCGGATCTTCCCGGGAGTTGACTCGAAAGGCCTCAACGCGTCCAGGCCTCGTGTCCACCTGAAATGCTCTTTCAACACGCCAGCCGTGGAGACATAAGCAGCGGCATGGGTCTTGCGGCAGGTGCTGCAGTGACAATGGCTGATCGGCATATCAATGCTGTCGATCTCATAGCCTACAGCCCCACAAGCGCAGCTTCCTTTCATTTTGTCCTCCGGTTTGGGCACTGTGTGAAGATCACGGCTTTTTGCAGTCTGACGGCGTTTGCCAAGCGACAAGCTCGACGTAGCTCGACTCCCCACCTCCAGTCGCACCCGACAACCAACCCCATACGAAGGACAGGGTGGTCCGCCCCTCGTGATCAACGCCTACCGTGCCACGAGACCAGCCGGACAGAATCTCACCCTCCGTGGTCAGGCAATGAAAAAGCAGCTCGATGGTCTCGGGGCCTGTCACGCGGCCGACCTGATGGCCCATGCGGATCTTGCCGCCCTGGTAGGTACTTGAAATGGCATCTCCCTCGACCTGGTAGTGAAACACCGTGCCTGCACCGGACAGCCCGTGGGTATTGCCTGCTACCGTGAATCGGCGATTGTTCAAACGTTCGGTGACTTGAGAAAAGGGGCTTTCCATGAATGTTGCTTCCTTGTAGTGGAGAGGGTCCATCTTAGCGTTGGAGTACTGATTACTTTCCGGGGAGCGATGCGATCATTTGATCAAATGCCGTTACCGAATATCTCCCATCAAGGTTGCCGACGGTGGGCATTTTTGAAGGAAACCCGAATCGCACTCTGCCGGGAAGCACTTCATCCATGGCTGAGTACCAAGTCAGCAGCGCTTGTTGGAGGCGCACGTGTAGCTCGAATTTGCTGCGTCGGCGGGTGGTGTCTGCTTTGGCACGCGCGCGCGCGAGCTGAGGATCGATGCGGCCAACAATATAACAGTCAGCAAAGCCAATACGTCCTTGTGCGATCGTTTCTCTTGTAGCGTCCAACTCTACCCGCCACTCGGGTTCGCTCGCCTCGCCGATTTGCCAAAGGCTCCAGATGTAGTGGAGCTTGAGAGGATCACTGTCACATAAGGCCCACGAAGAGGTGTCTTCCATGGCCAACGTTTGTTGCCAGCGATCCACGTTTCGCTCTGCCCAAAAGGTGGCTGCTCCGACTGGATTCTTTATCCGGTCCGGCTCGTTATCAAAACGGCCGTTTTCGGGAATGACATGCTGCTTTCCATGCTCGGCGCACCAAGTGGTTTTCCCACTGGCGCTGATACCTTCAACAACCAGGATCATTGTTATGACTGCTCCATTAATTGCGTCATTGCGGCACGCGTCAAAACCTTCCCGTCAGCGGATACTCCACAGCCAGGCGTATCTGGTCGGTGTCCAGTTCTGCCTGTGCGGTATTGCCCCGATGCACATTGTATTGCAACGACAGGGTGGTGCCTTTCGCCGCGCCACCTTGCACCACATGGCGCACCTGCAGGTCACGCTCCCAATGTTTGCCGCCTTCGCCATAACCCAGGTAGGCGTAGCCGCCTTGCGGGTCGACATGGCTTCCATCGATCCGGCTGCCGCGCACATAGGCGGCGCTCATGGACAGGCCCGGTAACCCCCAGGGGCTGGCATCGAAATCGTAGCGGGCTTGCCAGGACTGTTCATGGGGAGCGTTGAAGTCCGACAGCTGGACGGCGTTGCTGATGAAGATAGCGCCACGGGTGACGTAGTCAAACGGTGTGTTGGCGTCCACCTTCTGATAGCCGAGGCTGAAGCCATGGGGGCCTTGGGTGTAAGTGGACATCAGGCTCCAGGTCGTGCTGTCGATCCTGCCGGACAGCGACTTGCCCTCATCCGTGGTGCGGTACAGGTTCAGGTTGATCGACAACGCGCGGGTTTCACCCAGCGGCTGGATGAAGGTGCTACCCAGGTAATGCTGGTTCCAGGTGTCCTCATAGCGCGATGTATAGGCGCTGACGGTCAGCTTCTTTGCCGGTGTGAAGACCACGCCCGCGAGATCGAAGGCATTGCCTTTCACGGCGTTGGAGTAGTTGACCACAAAGCCCTGGTCATGGCTGCTGGCGTTCCGATCGGTACTTTCGCTGAAATGACCAGCTACCAGCGTCAGCGCCTCGAACTCGTTGCTTGTGAGAAACACCCCGGTGGCGGTCTCCGGGAGCAGACGGCTATCGGACGAACTGAATACCGGCGTTTTCACGCGCTGTTCGCCATAGCTCAGCACGGTCGATGACCGGCGCAGTTTGAGTGCCGCACCGCCGCGGCTGAACGCATCCTTGGGATGTCCCTGGTTGTCGAGACCGAGCAATCGCGCTTTCCCTGCGCGGCCACCGCCGCTGTCGAGTTGTGCCCCGAGGTAGGCATGGGCATCCATGCCCACCCCGATCAAGCCCTGGGTGAAGCCCGATTGCACCGTCGCCATCAGCCCGTAGGCCCATTCTTCGGCGTAGCCATTACGCTCATCACGCGGTTTGTAGGCATTACGCGCAGCGCCATTGCGGGCGCCATTGAGGTACTCGCGATGGTCGTAAACCGTGCGATTGAGCACGCTCCAGGCGCTGTCCTGGATAAATCCCTTGGCTTGCGATTGAACTGAATCGGCGAGTGCGAGAGGGCTTGCCAGGGCGAAGAGAATGGCTGATCGGGTATGCATTCCGGGGTGTCCACAAACAAATCAGGATGAGCGCAAGCGCAGGATGTGCGCGCCGTCGAAGGGGTCAATGAGGTAGTGCGCGTGCACCCCGAAAGTCTCCAGCAGGCGTCGCGGGGTCAACACCTCGAGCGGCTTGCCAAGGGCCACCAAGCGCCCTTTTTCCAGCACCGCCAGACGATCGCAGGTGAGTGCCTGGTTGAGGTCGTGCAGGGCAATCACGGTGGTCACGGGCAATGCGTGAACAACGTGCAGAATCGCCATCTGGTGCTGGATATCCAGGTGGTTGGTCGGTTCGTCCAGCAACAGGATCTGCGGGCGCTGGGCCAGGGCGCGAGCGATATGCACGCGCTGACGCTCGCCGCCAGAGAGGCTACGCCACGTGCGCCTGCAAAGATGCGTCGCATCGACGTCGCGCAAGGCTTGATGGACGATGTCTTCGTCCGCCTTCGACCATGGACTCAAGGCCGACAACCACGGCGTTCGGCCCAGGGCCACGGCATCGAACACACTGATCGCATCCAGGGTGTCGGCCTGCTGCTCAACCACCGCCAGGGTTTGGGCGATGGTTCGCCGGGACAGGGCCTTGAGGTCTTGGCCGTTGAGATGGACCGCTCCCCGGCTGGGCCCACGCACACCGGCCAGCAATTTGAGCAGGGTGGATTTTCCAGAGCCGTTGGGCCCGACAAGGCCCAGGGTTTCGCCACGACGAATGTCCAGGTGAATCTGGTGCAAGAGTTCAACATCGCGGATATGCAATCCGAGGCTGGAACAACTCAGCACGGTTTCGTCGGTAACCGGCGCAAGCGCATTCATCGGGCATTCCTCCGACCGACCAGGATCAGCGCAAACACCGGCGCGCCGACCAATGCGGTAATCACGCCGACCGGAATCACCTGGCCCTTGATCAAGGTCCGCGACAGCACATCGGCGGCCACCAGAAACACCGCACCGCCCAGCGCACTCGCCGGCAACAGGCGGGTATGCCGAGTGCCCAGCAACAGCCTGGCGGCGTGGGGAATGACCAGTCCAACGAAACCGATAGAGCCGACAATCGACACCATCACCGCCGTCACCAGGGCGGCGCAACTGATCAACAGAAATTGCACGGGACGAACCGCAATGCCGAGTGAGGCCGCGGAGTCGGCGCCAAAGGTGAAGGCATCCAGTGCCCGCCGGTGCCACAGGCAAACCGCCAGGCCGGCCACCGCAACCGGTACAGCCAGCCACACGGAGGGCCAGCGCACGCCACTGAGATTGCCCAGTAGCCAGAACATGATGCCGCGAGCCTGTTCGGAACTGGCCGACTTGGTGATTAGGAACGCGGTGAGCGCATTGAACAGTTGTGAACCGGCAATGCCCGCCAGGATGATCTGGCCGGTACTGCCGGGCGAACCGCTGGCACGGCCCAGCAATACCACGACGGTGAAGGCGGCGACGGCGCCGGCAAACGCCCCGGCCGACATCGAAATCGCTCCGGCACCCAGGCCCAGCAACGCCACCAGCACCGCACCCGTCGAGGCCCCCGCGGAAATGCCAAGCAGGTAGGGATCGGCCAACGGGTTGCGCAGCAGCGATTGCAGGATCACCCCGCAGGTCGCCAGGCCCGCCCCGCAAGCCGCCGCCACCAACGCGCGAGTCAGGCGGTAGTTCCAGACGATGCCCTCATCGATAGGATCGAGGACATACCCGGCCATCCACATTTTATTGGCCAACACCTGGAACACCACGCCGGGTTCGATGCGGGTTTCACCGATGGCCACGCCGGCGATCACGGCCACGAGCAGCATCACCAGTGCAAGCAGAGTGCGAATCAGCGTCGCGGTCATTTTGGCAGGTCGTAGCGGTTGATGGCCGTTGCCAGCGATTCGAGACCGTCGAACATTCTCAAGCTGGCCTGCATGGCCATGGCGTCGAGGATAATGATGCGGTTGTTTTTCACCGCGTCCATGTTGCGGGTCACGGGATCGCTGCGCAGGAATTGCAGTTTCCGTTGATAGTCGTCAGCCGGGAAACGCCGGCGATCCATGCGGGCGATGACCAGGAATGTCGGGTTGGCCTTGGCGATGGTTTCCCAGCCAACGGTTGGCCACTCTTCGTCGGACTGCACCACATTGCGCACGCCCAAGGTGCCCAGCATGAAGTCGGGGATGCCCTTGTGCCCGGCGACATAGGGATCGATGTCCAGGCTGGCACTGGAAAACCAGACCAGCGCGCTGGTGTGCGTGAGGTCTTTGCCTTGCACCGCGGCAATGGACTTGGCCAGGCTGGCCTGCAGTTGCGCGTTCAGTTGCTGCCCGCGCGCCTGGACATCAAAAATCTCGGCCAGTTGGGTAATGCTTCTGTAGAGACTGTCAATGCGAAACGGCTGCAGGCGGGTGCCGTCGGCCCCCACCAGGTTGTCCTTGGATTCGCAGTCCGAGGGCATGAGATAGGTTGGAATCTGCAGTTCGTGAAACTGCTCGCGGGTAGCGACTGCGCCTTGCGGGCCGACCATCCACTCAAGTTCGACAGCGACCAGTTCCGGGCGCTTGCCGATGACCGACTCGAAACTCGGCTCGTTATCGGCCAGGCGTTCGATCCTGTCGTTTTGCCCCTTGTATTTGCCCAGCACATCATTGAACCACAGCGAAGTGCCGACCAGTTTGTCACCGAGTCCCAGGGCGAAGAGCATTTCGGTGCCGGCCTGGCCGATAGTCACCGCCCGGACAGGGGCGTGCGTGAACGTCAGTGTGCTGCCGCAGTTCTCGATCGTCAGCGGGTAATGAGTAGGGGAGGCACAGGCGAGGGCAGAAAGTCCCAGGCCGGTGACGAGGGTGAAAAAGCGCGGCAACAGCATGATGCAATCTCCATTTGAACCGTACACGCAGCCAGGGTGCAAGGTCTGGAAAACACATCATCGAGCGCTGCCGAAAACAGCAGTGCAAGGCCCATCACCTGAGTGACGCCCGCGCAGATGTCCTTCCCGGACACCCCGCCGGTTAGTGATTTGTTGCTTGGCCGGCAGGTCTCCTGACTGATGCGTCATGGCGTGCTCCAGCCTTCCCGGGAATCGATCCCAGTGGCAGTTCAGGAGCAGGCTCGGCACCTACAGTTGCGGGGGCAGTTCCGTTTGATGCGTTGGCAGCATCACGGATTCCCTATGAATCCCGTTTGGGAACCGGCGGCGGCATGGTAGTCGATCATGCCGCCCGAGGCGAACCCATCGCCTGATCAGAAGTATTTGAGCCAGGCGATATCGCGACGACGCGCCTTCAATGCGGCGAACCAGCGCACCGGTGGATACAGCGTTGCCGCCAGGAGCACGGCGATCAGCCATACGGCACCTATGCCGTCGAAGCCGAAGTAGTCGCCCTGGTTCAGGCCGAAAAATGCCGCGCTGAGCAGATAAAGCATTTTCAGCACATACAGATGGAGCAGGTAGAAAAACATCGGTGCCGCGCCAAATACCGCCAGGATGCTGATCCATTGGCGCTGCCGGGCCCGCTCGAAGCCAAGCAGCAGTAAAAGCCCCACGCCCAGTGTCAGGCACAGGAACAGCAGGGAAGGGGGGTACTTGGTGATGTTGAAGAAACTCATGAGGGTTTCTGTCGTGCTTTCATGAACCACCCACTGCGCTTCGCCATAACCGTTGACCAGGCGCAGGGCGATGAAACCGATCAATGCACAGGCACCTGTCAGCAACAGATAACGCTGACGCATTGCGAACGAGGTAGAGCGTGCGAACCACGGACCGATGCAGTAACCCAGGGCGATGACGCCGATCCACGGCAGCACGGGGTAGGAGGTGCGCAGGCGCAAGTGGTCGGAGAATTCGATCCAGCCGCGATCATGCAAAATCGCCCAAGGCAGGTGCAGCGCCGATCCGGGCGGGAAGTGCAGGGGATCGAGCAGGTTGTGCAAACCGACTATGGCCAGGCCCAGGACACACAATATTGGCCGAGGTAGCCAGGCCAATACAGAGAGGGCAATCATGCTGACACCAATCGCCCAGATCACCTGCAGGTAGATCACAGCAGGCGGGAACTGAAAGGTCCAGGCGAAATTCACCAGGGTGAATTCCAGCACAACCAGGAACAGGCCACGCTTGAACAGGAACATCGACGGCGTGCCCTGGTGCTTTTCACCGTACAGGAATGCCGACAGTCCAGTGAGCAGAACGAACACCGGCGCACACAAATGTGCGAGGGTGCGGCTGAAAAACAACGTTGGCTCCGTGCTGTCGACAAGCATCGGGTCGGTGACCTGGCGGTGCAGGAAGAACGTCTCGCGCACATGATCCAGCAGCATCAGAAGGATCACCAAGCCTCTGAGGGCATCTATGGATATCAGGCGTTGGTTCAGGCTGGTGGTGGGCGGGGTTTGAACAAGGTTTGTCATTGAAAGTCGCAGGCAGGGGGTGGGTCATGCTGTCGGTTAAGAACCGATAATCGTTATGTTGTTATAACGTAACATAAATAATTGATTGTGTGGGCGAAATGCTATTTAACTTTGCAGGAGCCGGCTTGCTGGCGATGACTTCGTTGAGATCAGCGCCGGGCTCGAGGGCCAATCGGGAGACTAGCGGTCAATTACGAGCGGGGCGTCAAGACGGCCAAGGCAACCGCCACGATGAAGAGCGCCGGCACGTCACCTGCCAAGTGCCCCATTTGCCCTGGCTGGGTAACCGCCTGGACGGCCATGATGCCTCCATGTACAGCGCTAGACCACACGGTGAACCAGATGAGGCTCAGATTGGCTAATGGATCACGTGCGGCCAGGATCAAGAAGACGCCAAGTGTGGCGTAGATGCCAACGATCATCATCGGGTAGTCCGAGTGACCGACGTGCCAAGCCCAGCCGGACGGCCAGAACAACATAAGTGGGTAGAGAGCAAGGCACGCGAGGCCAGCCAAAACTAGAGCGACGCGTAAAAACCTGAGGCGATCGACTACGGTCATGGCGGACTCCTCTTCGGGGCTGGCTCTAAATAATAGGCTGAGGCTGCGGCCAGCACTTGGACATATTGATAAGTACCTCTAATCAATTCTCTGCAAAATACATCGTTTGTTTCCCTGTTTTTGCAGACGTAGCATGCATGCCGAAGCAGAATTGAGAGACATACATGTCGACACGCCGCGAGTTCATCAAGCAGGTATCGGTAGTTGCCAGTCTCTCCATCGACGAATCCACGACAGAACAAATTCAGCAAAAAGAATCCAGACTTCGCCGCCGGCTACATCAATTACTTCGTGATCAATGGTGCGGTCATTGCGCCCCAGTTCGGTGATAAGGAAGCAGATACGAAAGCCTTTGACCTGTTGTCTGAACTTTACCCGGACCGCGAGGTGGTGCAGCTCAACATCGACGCAATCGCCGCAGGTGGTGGCGGCATCCACTGTGTGACCAGTCACCAGCCTTCGGTTTAGTCTGGATTATGTAAATCCTGAGATTCAAAGCCCTCCACCGAAGCGATACTGCCAGACGATGCCAACGGCATCGTATTCACTGCCGGTACGGGTATGCGCACCTTCACTCGCAAACAGCTTTAGCGAATTATTTCGGTTCAACGGCAGCGAGAGGGTACCCCCATAGCGTGTATTTTCCTGAAAGTCGTGGTTACCGATCCCATCGACTGAGGTACTCCCGCCAGCGAAGTAGGTCCCATCCAGCGAGGCCCAGACACCGTTACTAAAGGCATAGATAAGATGCACCTGTGCCTGGTAAATCGGGTTCTGGGAAAAAGTACGGTCACCAAGGTACTGGTTATTGTCGGTGTAAAAGGTTCCCGCAGCGGATAATTCCAGGGTCACGGGGCCCAGGCGCTTGGAAACCCCAAGTTCGGGTTTGAATGACCAGCGGTTGTTGCCGAGATTGACCAGCCTGCTGGAGTCGTATTGGCCAAGTGGCGCCGTAATTGCCAGGCTGGCGCCGATAATCACATCTTGTTGATAGCTGGGGAACTCAGCCAGGGACATCGCCGGGGCGCCCCACAAGTTGACCGAGAAGCGCAATCTTGGATCAATCAGCCCAGTGACATTTCGCTCCCTGGGTTCACCGGCAAACAGGGCCGAGCCCGTCAATCTGGCTTCAGGCACGACGATGTCGAACTTCCCGGAGCGGCCCCAGACGTCCAGGGACCTGGCGAAGGCAAATACGACCGTCTTGATGTGGAGTTTGGCATTCTGGAGTGGGACGGAGGGGTTGGCGGTCACGTTGCCATGGAGATCGCTGTAGCCCAGGAGCAGGAAATTGATACCGACCGGCGTATTGGCGTAGGACCTGGGTTCAAGATCCTCTGCGACGGCAGTGGTGGCTACCATGATGAGCGATGCGGATGCGACCCGAGCCAGCCTGGCGATGCAGAGTTTGTGTTTCATCCACATTCGCTCGCTTCCTGTCAGGATTTTCAGGGTTCTATGTGTTGTTGTAGCACTTCCCTGCAGGAGCGAGCATGCGCGCGAAAAACCCGAGGCCGCCACGGGGTATCAAGCCCCCCCGCGTTATCGTTGAAGACCATCGCGAGCATGCTGAACTGGTCAAGTAATCATGCTCGCTCCTACAGAAAAACGGGGTGAAATCCACGAAATCCGGGACCCACATCAAAACCCCACATCCAGCACCACACTGTCCAGATAAGTCCCCGCTGGCGGTGTCGCCTGATCGGTGTAGATCTTCGCGTTGTAATTGAAGACCTGGCTCCCCGTCCCCAGTCCATTTCCGGGATTGACCTCCGCGTCCGAACTGGCCCGACGTGCACTGCCCACGCTCCCCCAGCGGGTCGTGCCGGCACTTTTGAAAATGTCATAGGCCAGGTAATTGCCGCTTGAGATCATCCGTCGTCGCCCGCCGACACCCAGCGGGTTTTGCCCATCGCTCAGTCCCACCGTGTAGGCGCTGCCTTTGGTACAAGCCAGATTGATGGTCTGCCCGGTGACCGGGGCGAAAGCACTGACCACCGGCGCGCTGCCGAAGGTGATGTTCGGGGCGGTGATGGTGCAGTCGTTGGCAACCGTCAGGTTGATCGTCAACGTGGTGGTGCCGCTATTGATGTCGCGTCCCAGGCATAAGCCGCCAACGCCGATGCCCGAGCAATAGTTCCAGTTCCAGAAAATGCTCAGCGTTTCGCTATAGATCCCGGCCGCGACGTTGCTTCCAAGGGTGGTGCCGAAATACAAGGGCACGGTTCTTGGGACCGTGCCACCGAGCAGGCCAAGTGCATCGATGATGCCGTTGCGCGCGAAGTCGTAGGCGGTGCCGCGGGTTAGCGGGTAGCTGGTGCTGTTGTTGGCGTAGATCGTGTAGCCGATGACGTCGCCGGTGGGGCCGAGCAAACCGCTCTGGGTCGATGTGACCGTGGCCCAGAAGTGATCGTTGCTGCTCAGCAAGGACAACAGCGAGCCGGTGCAACTCAAGCCGCCGTTGAGCGTGGAACCGGGTTGCGAGGTGGTGCGCACGGCAATCGAACTCAATAAGCCGAAGGCCACTGGCGTAGTGCCGACCACCGAACACAAGGCCCAGGCGGGGGCCGGCAGACAGAGCGCCAGCAGCATCAACCACTTCATCGGCACACCAGCGGCCCGATCAGCGGGATCTGGTCCTGCGCCAGGTCGGCGGCAAACTGCACGTGGCAGGTCTTGCCATCGCCCAGCGTCACCCGCAGATCGTTCTGCGCCTGCAGGTTTTCCAGGTACACCAGGCCGTCCCAACCGACCACCGTTTGCGTGCCGCTCTGCTCATGCAGCACACCGCTGCCCAAGGGCAAATCCTGCTGCTGCACGTCCACCAGCACGATGCTCGCGGCGATCACCCGGCTTAACGGAAACTCCAACAGATAGCCGCTGCCACGCCGCACCGCAATGCGCTGCTCGACGTTAGGGCTGCGCACGTTAGCCGGCAGGTTGAGCGGATCGATCTCGTATTTGCCGCGGTAGTAGGCGCTGCTCCACGGTACCAACAAATGACCGTTGCGATCGGTCTGGCCCACCTGCTGGTTTTCGTAGCGCACCGGAATATCGGCGTAGCCGTCGGTGCTGACCACCACAAACGCATCGTCGATACGGTTCGCGGCAAACACCTGGCGGTCCATCCACACCAGTGAACCGCTGGCATCGGCCCAACGGGTTTGCGCATCGCTGGTGCCATAGACCCCGGCCTGCAACTGCACCGACTGCAAACGCCAGGTCAAGTCGGCCTGCCGGTAATCGGGTCCGTCACCCTTGGCGTAACCGAGATTGAAGCCCACCCCGCCCTCGGTCGGCACGGCACGGCTGTAGTTGACCCGCTGCTGCGATTGGCCGGTCTTGCTGCGTTCACTGCCGATGGCCAGGCTGCCACGCAGGTCGAACGGAATCACCAGTTGCGCCTGCACCGCCCAGTTGCTGTCGCCGATTTCGCGGTTGGCCGACAGGTAAAAACTGGTGTTGCGCCACAACGGTTTGCTCCAGGTCAGGTTAAGCAGGCGGGTGCGCGAGTCGTCCGCCGCGCGCACGTCGAAATAGCCGGCGCCAAGGCTGCCCCAGGTATCGAGATTGACGCTCAGGGTTGCCTGCTCGCTGCGTTTGCTGAGGGTGGTGTACGGACTGTCGACCACGGTCAGGTCGGCATATTGATCACGCCGTTGCAGGCGCTGCCAGGAAAAGCTGTAACGCTGGCTGCTGTATTGATAACCGAGGCTCAGTTGCTGACCGGTTTGCCCGTCGAAACGGCTTTGGCTGACGGCGCTGTTGAGCACGCCGAAATTGCCCAGCCGCACATTGCCGCCAACGCCGCCGAGCGCCAGCGTGTCCGAGGCTTCAGCGTGGCTTTCCAGGGTGAAGTTGTCACTCAGGCCGTAACGCAAACTGCCGGACGTGACGCCGGGGCCATAACTGAAATCCTGAAGGCCGTAGTCCTGGCGCAAAGTCCCGGCCGCCACGGAAAAGTCTGACAGGCCTTTTTGCAACAAGCTGCTGGTGACGTAGAACGGCACCGTGGTCGAAACCTGACGTCCCAGGGCGTCGGTGGTGACCACCACGGCTTCGCCGGCACCGTTAATGAACGGGATGTTGGTCAGTGTGTAAGGGCCAGGTTGCAGATCGGCACTGCTGGACTTGTAGCCGTTGATGAACAGGTCCACCGACGACGGCACCGCGGCTTCCCCGGCGAACTGCGGTAAGGGGTAGGTCACCAGGTCCGGGCGCACGCCGAAGTCGCGCGACAGTTTCACGCCGCCCAGGCGCACCGAATTGCTCCAGGGCAAGGCACCGCTGACCAGATCGCCTGCCTCGTAGGTCAGCATCCGATCATCGTCGGAATAGCGCCAGGTGGTGTCATAGCGCAGGTATCCATTGTTCAGCGTGTTGATCGCGTCCCCGGACAAAGTGCGGCGATATTGCCCGGTATTCGACAGCGTGCCCCAACTGTCGAACAACCGCACTTCGTTCCACGCGGCCAGGTAAGTGCCGGCATCATCGGTGTCGTTGAGGTACAGGTCATAGTTGAGGAGGGCGCCGAAGCTGCTCAGGGCCGGGGTACGCGGATAGACTTGGCTACGGCCGACAAACTGCTCCGGCAGCCAGTCGGGCGGCACATCCAGCAACAGGCGTTGGGCTTTGCTGTCGTACTCGCTGTGCAGGCCGGGCAGGGTGTCGAGGCCGACTTCAGCGCCGATGTCTTGCGGCAGTTTCATGCCGGTTTCATGCAGCGCACTGGCGGGCACAAAAAATCGCCCGTTGCGCTGCTCCACCGCCACGATCCGTCCGGTGTTCATCTGGTTGACCACCAGTTCCAGAAACAATTGTGCATCGGCAACAGCCTCCATGCCGCTGGGCGGAGGCGGCAGGTCTGCGGCCTCTGCGTGATGAATGACAACCAGGCAACACGCACAACCCATGGCCCTCAACGGACGCCGCAAACTGCGAGCCCACCCCTGGCTCATTACCGCTTTCTGTCCGTCAATGGACCTGGTCTCCTTTTACTCCCCTCGCCACGAAAAACTGACCAGCACTACGACCTCAGCGTGCCGGCGCAATACTCTGCACCTGCGGCGCACCATTGACCCGCACCTGCAACGCCGGGTCGCCAGCCATCGGGCCGGGTGCGGGCCAGCGCATGATCGCCCCGGGCAACACATACCCCAGCAATCCGTCCACCAACGGCCGGGTCTGGCTGCCTTGCTTGAGAGCCACATCGGTCAGGCGCGCATGAACCGCGCCCTGGTTGCGCACCTCGACATAAGGACGGCCGTCCACGGCCACCGTGCGCCAGCTCAAGTCCGGCAGGCCGACGCCTTTCGGATCGCGCTGGCGGGTGGTGTCTTCCTTGCTCCACAGACCCGCGCCATAGGCGAACAACGGCACCGAGTAGCGCATCTGAAAGCGAATCGCCGCCGCCGTCTTGCCGTCGTCCGCCGCGGGCGGTTTCGCCGAGGGAATTTCATCGATGATGATGCGGTACGCCAGTTCCTGACCCGGCGGGATTTCCCGCGTGCGGGTCAGGCGCACCAGTTGTTTCTGGCCCGGTTCGATCTTCGCCACCGGAGGGCTGCCGATCACGTCACGCTGGTTCTGGTATTGATCGCTGAAGCCGCTCTGGCTCCAGGAAAACACGCGTATCTGCAGATTGGCGGTCTCGCTGCCGCGATTTTCCAGCCACAAGGCACTGGCCTGTTGATCGGCCTCCAGCACCGGATCGATCGGCCAGATCAGCACCGAACTGGCTGCCTGCACCTTGGTTGCCCCCAACCACAGCAGTGCCAACAGCATATGACTGACGACCAACCGCCGTCGCGAAGGTGAATACATGTGCCTGCTCCTTTTTGCCCCTGCGGCTTGATCCGTTGGCCCCGTCACCACGACAACTGCACTTGCAGCACGTCGCCGTACGTCCCCCCGGGTTGATTGCCCGGTAACTGCACCTGGCCGTAAATCGGCAGGCTGATGTTGTTCGCATCGCTATACGACACCGCCACGCTTTGCCCGATCCCCAGGGTCTGGCTGTAGGCCGCATCGCGAAACAGTTGATACGCCACCCGGTTGCTGCCGCTGGTCAACTGCATGTGGCGGCCACCGCTGTTGTACTGTCCGCCATCGACGCTCATGTTCAACGTCACGCCCGGCGTGCATTGCAACTGCACGCCCCCGGTCAGTGCGACTTGCACCGTGTCCGTGGCGAGCGCCGAGCGGTTGCCGAAATTCAGGCTGCCGTAAGTGGAGACGCCGCCGACGATCAAGCAGCCGGCCGTCACCGTGGCGCTGACCTGGAAGCTCTGGCTGGTCGCCGCCGTGAGCGGCAGCGGCAAAACACCTGCACCCAGTAGGAGCAACCATGCACAGCCATACCGGCGCATGGCGCTAGAACGTCAGTTCGACAGAAATCGTGTCGGTGTAGGTGCCCGCCGGCAAACCGGCCTTGCCCACCGCTTGGCCGTAGATGTTCACGGTCTGCGCCACGCCGGTGCTGGCGGCGAGGTTGATTACCCCGTCAATCGCCAGGATCTGCGAGTGTCCGGCATCGGTGTACAGGTCGTACGGCACATAGTTGGCCACTCCGTCGTACAACGCCCGGGTCCCGCCCTCGGATTGGCCATCGTGGGCCCCGGCGCGCACCTTGACCGTTGGCGTGGTCCCAGCCGAGCACAGAATCGACAGCGCTCCGCCGCCTCCACCCAGCACTTGCCCGGTGGCGGTGGTGAACAGGCTGTTGGCGGTGCCGAAGTTCAGGGCACCGAAGTTCAGATTGGTGGAACCGCCACCCCCGTTGACCTGGCAACTGCTGATCAGGACCAGGCTGGAGGTGATCTGGCCGGTGACGGTGGTGGCAGCCTGGGCGCCGGACGCCAGCGTCAGGCCAAGCAATGACAAACCTATCCTTGATGCAAGCGTGCGCATGGTGTCCGTCCTCTACGGGGTTACCAGTCGAGCGTTACCGTCAGGGTGTCGGTGTAGATACCGGCGGGTAACGCGCGGGTGTTCGCCACCACCGAGCCAAATACCGGAATCGGTATCTGCGCCCCGCTGGTGACAGCGAAATTGTGTTGTTGGCCGATGCTGTAGCTGCGGTTGCCGGAGGCATCGAGGAACAATTGGTAAGCGATGGTCCGGCGGCCGTTGCTCAAGCGCCGGGTGGTGCCGTCGCCATGGGTGCCGCCATCGATGGTGACGGTGAAGCCCGTGACGGAAGGGTTGCAGGCCACGTTCAATTTGCCGCTGGCCTGGTTACCGATACGCGCCTTGATCGGGTTGTTCCAGGTCGGGCCTTGCTGACCGAAATCAAGGGTGCCGAAGTCGCTGACCGGGCTGTCGGGATTGCCGCCGTTAGTCACTTCGCAGCCGGCGATAAGGGTCAGCCGCGCCTGGATCTGCCCGCTGGCGGCCGCTTGTGCGACACCGGACAACAGTAACAACGCGCCCACGGCGAAAATCTTCCAGAACCTGGTCATGCCACCGATCCCAATTCCTTCAGGATTAAACATACGGTCGTTCGCTCACGAACGCCTCCTTCCCTGCACAACCCGGACTTCGCCTGGGTTGTTGATTGCTCATGCGATTACCAGGTGAGCGTCACCTTCACCAGGTCTGAATAGCGACTGACCTTGGGTATCTGTGCCAAGGGTTCGATGCGGGCGTACAACGGCAAATCCACCGAGCCGGTATCCGGCACGCGACCGCTCACCGGCACATCCACCGCCAGCGGAATTCGCCGTGCCGGGTCTTGATAGAGTCGATAAGGAATGGGCTTGCTGTGTTCGGCGCTACCAGCCATGTAACGAACGTCGCCGACGCCACCGTGCAGGCCGCCATCGACGCGTAGTTGATAAGGGGTATCGGGATTGCATTCGAGCCTTGGCAGGCGCTCGTTCATCAGGGCCGCCCCGAGCGGCCCCGCAGGATCGTCCAGGCGTGCGCTGCTGCCGAAGTCCAGCACGCCCAATTGCTCGACACCCGCGGTGCGTTGTTGCCCGACCAGTTGGCAGCCACGTTGCACATCGACCCGCACCTGCACCTGGAGTTCTGCGGCCGACAGGGTTGCACTGAGCCCTACGCTCAAGACTGCCAATTTCACTCGTCCATCCAC

Protein sequences of DBSCAN-SWA_3

>NZ_CP051487|2991139:3032300|3013939_3014431_-|WP_168757950.1|DBSCAN-SWA
MKTLSIDNSSTNVQSSSTLGIKTMALGTYGAYFALAVIYFWFGGMKFTHYEAVGLVPLVSNSPLLGWVYDIFSVDTFSSLLGILEVSIGVLIAGRLLSPKLSLIGAALSAGLFFTTLSFMFSTPGVIEPGLGFPGISVAPGQFLLKDIGLLAASIFIAGHSLT
>NZ_CP051487|2991139:3032300|2996176_2997250_-|WP_168759169.1|DBSCAN-SWA
MFLIERYVIAEIRRPVIVMVSILVFIFASYSVERYLADAVEGTLALQAVLEMVFYKVLIALEMLVPVALYASVTLAVGRLCHDSEIIAIAASGASPLRIYRAVLLLAIPISLAVAMLSLYGRPWAYTQAYVLEQQSRTDLDVNHLQAQRFNLNNENGRMILAERIDRTDGRLHDVLIYDPGDSKTRVFRARQARILDPNPDDPIVELTQGHSYLLKHSASRDISEKFEHMRLHLLPIERAAEGKRKAAPNEVLQASSAPSDKAELQWRQTRGVSAMVLALLAIPLSRTRPRQGRFATLLPVTAVFAVIYYAADICKTMVGNSTLPLYPGLWTVPLLMSLALLVFLARDLANFRFGYR
>NZ_CP051487|2991139:3032300|3019289_3020081_-|WP_168757954.1|DBSCAN-SWA
MNALAPVTDETVLSCSSLGLHIRDVELLHQIHLDIRRGETLGLVGPNGSGKSTLLKLLAGVRGPSRGAVHLNGQDLKALSRRTIAQTLAVVEQQADTLDAISVFDAVALGRTPWLSALSPWSKADEDIVHQALRDVDATHLCRRTWRSLSGGERQRVHIARALAQRPQILLLDEPTNHLDIQHQMAILHVVHALPVTTVIALHDLNQALTCDRLAVLEKGRLVALGKPLEVLTPRRLLETFGVHAHYLIDPFDGAHILRLRSS
>NZ_CP051487|2991139:3032300|3001759_3003490_+|WP_168757943.1|DBSCAN-SWA
MSATFSNQALTQRLADFPTLVEALDYAASGLGGMNFYDRHCRLNAALEYSTLRSNAVSIAQRLLGLKLNKGDRVALIADTHPSFIESFFACQYAGLIAVPLLVPASLGSHRSYVDKLKGLFANCTPAAVLGVEEWLPYIREALGDTRQVFVGTLEALGELPALQTLPTVVPEDIAYLQYTSGSTRFPRGVIITQRAVMANIRGIVVDGVGVRAGDRCASWLPFYHDMGLVGFVLAPMAAQLTVDYLHTRDFATRPGQWLKLISQNRATVSVAPPFGYDLCTRRVRDLEKTPLDLSCWRVAGIGAEPIRASVLSRFAECFLDTGFDPAAFTPCYGLAESTLAVSFARRGVGVQVDHVARSVLEHQLRAQASAADDPASCAFTNCGAPLPGHRVEIRNAAGRQVAEREVGQIFVQGPSVMSGYFNDPQSTWAVLEDGWLNTGDLGYLSQGELHITGRSKDLLIVRGRNIWPQDIEYLVESEPELRPGDAIVFVVPVDDETQVVVQIQCRIREPEGRERLVRTLVAKITSEFGLTADVHLVPPHSLPRTSSGKPSRAEALERFLAQANTDLPYPALEVT
>NZ_CP051487|2991139:3032300|3004439_3004700_+|WP_168757945.1|DBSCAN-SWA
MITEEAILKKVMEIIEPFAPSGMVIKPNSDLTGDLGMESIKVMDMLWVLEDELKMSIPLNILMDVHTPDQLAHAILTLTERKNGTV
>NZ_CP051487|2991139:3032300|3023836_3024205_-|WP_168757957.1|DBSCAN-SWA
MTVVDRLRFLRVALVLAGLACLALYPLMLFWPSGWAWHVGHSDYPMMIVGIYATLGVFLILAARDPLANLSLIWFTVWSSAVHGGIMAVQAVTQPGQMGHLAGDVPALFIVAVALAVLTPRS
>NZ_CP051487|2991139:3032300|3015905_3016364_+|WP_168757952.1|DBSCAN-SWA
MLDDATPQGNECPVARTLEAIGDRWSLMIIRDAFDDIRRFSEFQKSLGVAKNILASRLKTLVEIGIFDIRPASDGSAYKEYVLTEKGREIFPLVVCMRQWGERFLFEPQETRSVLLDNASGKPLMPIEVRSASGQTLRPADCHRVRLVDGES
>NZ_CP051487|2991139:3032300|2995097_2996180_-|WP_168757942.1|DBSCAN-SWA
MKVLDRYITRHVFFGFAAAAALLLPLFTTLDLVGELDDVAPGGYRLSQAIEVVFLTLPRRVVELGPFIALLGGIAALGQLSATRELTVMRATGLSIARIGFTATLAGLALALSWAALDEWVASPLQQNGLELRNEAIAAGAQASNDQGSVWARQDDQIVRIGNLAHKRLPVNIEIFRFDNDRSLVSYIFAETADILDAGQWRLNNVQVKQWDQGAETTQQLDQMPWRSIFGSARLGDITLPTESLSARQLYRYIAYLKGSGQPSAQYEMAMWQKLGRPILTLAMILFAIPFAFAQPRSPNLGARLALGALVGLMVYVSNQIIVNLGLLLKMNILVTTLGPALVLLAVAIVIVAYLDRGSR
>NZ_CP051487|2991139:3032300|2992878_2993841_-|WP_033045682.1|DBSCAN-SWA
MHEACPPPPAKLLEQIREQCTQPMPDEVQAIVQALHTRLGDTLVALLVYGSCLRNGDLTDGLVDVYALVDSYAHAHHSRLQQLANAWLPPTVILVRAAAADGQILHAKCAILSLQDFEAGTGSWFQSYLWARFAQPCRLVYFKDEETRKRIHFALAQAVMTLMGRCVATLPDRFDSFTLWEKSLSLTYRTELRPESADRPRQLVRHDMDYYSRITQAAAPAVKQMAACAGEEDRYRNLCPMATRRGNERLWKWRRVQGRTLNVARLVKSFFTFENGVDYLIWKLERHLGEPVVVTHRLRRFPLLFGWPLLWRLLKSRRLR
>NZ_CP051487|2991139:3032300|3003486_3004404_+|WP_168757944.1|DBSCAN-SWA
MSARVVSLTGATGFIGSVLRERLITRGVEVRALARSRSAMTADGTKWIIGTLEDEQALAELTRGADTVIHCAGKVRGRNARDFDEVNVQGSKRLMEAARMSGSCERFLLISSLAARYPTLSWYAASKFEGECQVREAAGTIPVCIFRPTAVYGPGDRELRPVFEWLLRGWLVTPGKGDSLLSFLHVDDLVSAVMQWLDAPVMQSQTFELCDGQAQGYDWASLASIATDIRNAPVRQAVVPAKVLKGIARANLVLSRFTRQAPMLTPGKVNELMHPDWTCSNARISAVLGWEPQILLGQALRNHLY
>NZ_CP051487|2991139:3032300|3010967_3012770_-|WP_168757948.1|DBSCAN-SWA
MTDLLLNERELRFQLYELLDTEALLQRPRYAEHDRGVFDASLTTARQIAAELFAPHNHKGDANEPTFDGERVHMIAETKVAWDAFAQAGFLAAHHDFADGGLQLPEVILRACMAYFNAANISTVAYSFLSIGATNLLRAFASPPLLERFLAPMLDGRFSGTMALTEPGQGSALGDLRTLARPAENGTYRIFGQKMFISGGDHELTENIVHMVLARIEGAPAGTKGISLFLVPKFLVNADGSVGARNDVALAGLLHKMGYRNTTSTVLSFGEHDGAVGYLVGEEHQGLSYMFQMMNEARIGVGLGAASLAYQSYIHALDYARQRPQGRLPGNKNPAAPQVRIVEHADVRRMLLQQKVYAEGSLALCLYASSLVEDAHTATTALARNNAGELLDLLTPVVKTYPSRYGLLASEIGVQVLGGAGYTREYPLEQYYRDNRLNPIHEGTEGIQAIDLLGRKLGPRGGDGYRLFTAEVLATLLTANSDPHCAPLAALLADALRVLEQVTASLQTQVTADANLGMANATPYLDLFGRVVVGWIWLRQALLASRALGSGAGDSDADFYQGKLQAAHYYMTWELASLESQGRLLTEANHVAYYMQDRWF
>NZ_CP051487|2991139:3032300|3030072_3030573_-|WP_168757962.1|coat|DBSCAN-SWA
MRRYGCAWLLLLGAGVLPLPLTAATSQSFQVSATVTAGCLIVGGVSTYGSLNFGNRSALATDTVQVALTGGVQLQCTPGVTLNMSVDGGQYNSGGRHMQLTSGSNRVAYQLFRDAAYSQTLGIGQSVAVSYSDANNISLPIYGQVQLPGNQPGGTYGDVLQVQLSW
>NZ_CP051487|2991139:3032300|3016412_3016808_-|WP_033043439.1|DBSCAN-SWA
MKGSCACGAVGYEIDSIDMPISHCHCSTCRKTHAAAYVSTAGVLKEHFRWTRGLDALRPFESTPGKIRHFCSHCGSHLAAERNGSSAMIVRVATLDEDPGSRPEYHIWTEQDVAWLNGEGLPGYSQWQPGR
>NZ_CP051487|2991139:3032300|3029239_3030028_-|WP_168757961.1|DBSCAN-SWA
MYSPSRRRLVVSHMLLALLWLGATKVQAASSVLIWPIDPVLEADQQASALWLENRGSETANLQIRVFSWSQSGFSDQYQNQRDVIGSPPVAKIEPGQKQLVRLTRTREIPPGQELAYRIIIDEIPSAKPPAADDGKTAAAIRFQMRYSVPLFAYGAGLWSKEDTTRQRDPKGVGLPDLSWRTVAVDGRPYVEVRNQGAVHARLTDVALKQGSQTRPLVDGLLGYVLPGAIMRWPAPGPMAGDPALQVRVNGAPQVQSIAPAR
>NZ_CP051487|2991139:3032300|2998136_2999279_-|WP_020801069.1|DBSCAN-SWA
MINKKLPIITRPVLTSLDLKTFISFPGTLYRNDPCWIEPIHYERHELLSQKNPASPHLTWQAWLAWSGTEVVGRITAQIDSLHRQLHGHDSGHFGMLEAVDDPAVFDSLFAAAEAWLREHGAARITGPFNLTINQESGLLVEGFDHPPSAMMGHGQRFYDQRLAALGYRQAKDLLAYWMRTDQLHFPPALSAMMARERKRVVIRPLDPRQFRRDMRILREIFNDAWSRNWGFVPFTESEFYELGSQLRLLVPKDLLYIAEVDGEPCAFIVAMPNINEAIASLDGRLLPFGWIRLLWRLYVKGARTARVPLMGVKQAYQFSRLGPALALLLIEALKPPFVKRGIEALEMSWILESNAVMRKILEQIGATAYKRYRIYEKHI
>NZ_CP051487|2991139:3032300|3013033_3013879_+|WP_168757949.1|DBSCAN-SWA
MDRLSTLFSQFGVRANLFYNGRLCGLASYDGAQGRGYVHLLQAGSVTLLGADRKDLLLTRPSLIFMPRPSRHQLFANESEGAQLLCASMEFEGGIDNPLAASLPDCLVLSLDELPMLADTLKWMFGEAASAHCGREAALERLFELLIILLFRHLLDHQQLRTGMMAGLADPRLARSLVQIHNAPERAWSIAQLASESNMSRAAYAVHFRDVIGQTPAEYLLSWRISLAQKRLREGRSITLIAAEVGYESPSALARAFRRKTGCSPRDWVKDLAGDDDGAMA
>NZ_CP051487|2991139:3032300|3007850_3008627_-|WP_033043596.1|DBSCAN-SWA
MNENPGFSLIGKTVLVTGASSGIGAHLARVASDAGARVVLGARRVERLQQLADEIRQTGGEAMAVALDVTDRDSVEAAFDAAQAAFGVVDVVLNNAGIGNGQRVLEISEADWRAMLSTNLDGVWRVAQCAAQRLAKAQRPGSIVNIASMLGLRVGTGYSHYCAAKAGVVQLSKSLALELARYQIRVNAIAPGYFKTEMNDEYFDSEKGQAYIRDTVPMRRLGSLQELEGPFLLLASEAGAFMTGAVLAVDGGHLVGSL
>NZ_CP051487|2991139:3032300|3016839_3017235_-|WP_020797743.1|DBSCAN-SWA
MESPFSQVTERLNNRRFTVAGNTHGLSGAGTVFHYQVEGDAISSTYQGGKIRMGHQVGRVTGPETIELLFHCLTTEGEILSGWSRGTVGVDHEGRTTLSFVWGWLSGATGGGESSYVELVAWQTPSDCKKP
>NZ_CP051487|2991139:3032300|3025846_3026809_-|WP_168757959.1|coat|DBSCAN-SWA
MKWLMLLALCLPAPAWALCSVVGTTPVAFGLLSSIAVRTTSQPGSTLNGGLSCTGSLLSLLSSNDHFWATVTSTQSGLLGPTGDVIGYTIYANNSTSYPLTRGTAYDFARNGIIDALGLLGGTVPRTVPLYFGTTLGSNVAAGIYSETLSIFWNWNYCSGIGVGGLCLGRDINSGTTTLTINLTVANDCTITAPNITFGSAPVVSAFAPVTGQTINLACTKGSAYTVGLSDGQNPLGVGGRRRMISSGNYLAYDIFKSAGTTRWGSVGSARRASSDAEVNPGNGLGTGSQVFNYNAKIYTDQATPPAGTYLDSVVLDVGF
>NZ_CP051487|2991139:3032300|3022478_3023645_-|WP_168757956.1|DBSCAN-SWA
MTNLVQTPPTTSLNQRLISIDALRGLVILLMLLDHVRETFFLHRQVTDPMLVDSTEPTLFFSRTLAHLCAPVFVLLTGLSAFLYGEKHQGTPSMFLFKRGLFLVVLEFTLVNFAWTFQFPPAVIYLQVIWAIGVSMIALSVLAWLPRPILCVLGLAIVGLHNLLDPLHFPPGSALHLPWAILHDRGWIEFSDHLRLRTSYPVLPWIGVIALGYCIGPWFARSTSFAMRQRYLLLTGACALIGFIALRLVNGYGEAQWVVHESTTETLMSFFNITKYPPSLLFLCLTLGVGLLLLLGFERARQRQWISILAVFGAAPMFFYLLHLYVLKMLYLLSAAFFGLNQGDYFGFDGIGAVWLIAVLLAATLYPPVRWFAALKARRRDIAWLKYF
>NZ_CP051487|2991139:3032300|3008680_3010792_-|WP_168757947.1|DBSCAN-SWA
MSNLVTYHVEDNLALIGLASKPVNALGQPLRAAILDACERAASDPAVSAIIVHGANGLFCAGADISEFGLPGSFAAPSLPDLLLRLTQIDKPLIASIDRFALGGGLELALACGYRISAADSRLGLPEINLGLLPGAGGTQRLPRLIGAEPALEMMISGQPVSAGRALELGLIDRLPGDGECLLDGARHFAQELIRESAPARPAERHANPAAALPEGYFTDYRASHEPRWKNRLAPRLLLAAVESACVLPLQAGLQREVALFKEAEASTQSQALRHVFFAEREAGKVAGVTANTALRPVARVAVIGAGTMGGGIAMNFANVGIPVTLLELKPEALERGLGQIRSSYEISRQRGKLTQEQLDQRMALLTGTLDYADIAECDLVIEAVFESLPIKQQVFRTLDEVCKPGAILASNTSTLDVDQIAAVTRRPQDVIGLHFFSPANVMRLLEVVRGKLTAPEVLATTLKLGKTIGKIPVVSGVCFGFIGNRMLEPYSREAHRLVLEGATPAQIDQVLTDLGLAMGVMAMHDLAGIDVSFLVRESRREAIAHDPSYCRLADELNALGRFGQKTRRGAYIYEGRERKEDFEVITLAERIAGELDIRRRPIATQEIHDRCLFMLINEGIQLLDEGIAERSGDIDLVWINGYGFPAWLGGPMHSAEQIGLDKVLDGIRHYRKALGEYGEMWFHPAPLLEHLVAAGKTRIERI
>NZ_CP051487|2991139:3032300|3031772_3032300_-|WP_168757965.1|coat|DBSCAN-SWA
MDGRVKLAVLSVGLSATLSAAELQVQVRVDVQRGCQLVGQQRTAGVEQLGVLDFGSSARLDDPAGPLGAALMNERLPRLECNPDTPYQLRVDGGLHGGVGDVRYMAGSAEHSKPIPYRLYQDPARRIPLAVDVPVSGRVPDTGSVDLPLYARIEPLAQIPKVSRYSDLVKVTLTW
>NZ_CP051487|2991139:3032300|3005947_3007675_+|WP_168757946.1|DBSCAN-SWA
MRIIFAFGRSYPARTVLMLLSLLLAGVVESVSLSTMLPLISAMLEDQPHSKLAVYVFGAMNSIGLQPTIANMLVVIVVGMTLSNLLILLGNRQVGYTVAHVATDLRVSLIKALLGSRWEYYLRQPSGALANAVATEAFRASTAYEHAANMLALGIQAAAYALIALFVSWQAAILSLVIGFVLLAAVRGLVKTSRRVGKSQTRLMRELLVHLTDTLGSVKPLKAMARDDIADSLLRRHAGELNTALEREVMSRETLRALQEPMLAILAAAGLYAGLVIGGMPLSSVMVLIFVVVRMLGLLHKAQQRYHRMAAQESAYWAINESIDNAIADAEPVGGTCTPSLQRHIAFENISFGYGGRQVLNNVSMNFPVGSFTTMIGPSGSGKTTVLDLICALLAPQSGRIRVDDCDLHALDRKAWRRMIGYVTQETLLLHDSILANVTLGDRALNAADAERALRQAGAWQFVQECPGGLQSIVGERGAKLSGGQRQRIVIARALAHRPRLLILDEATSALDPESEAEICQVLKNLTPGITVIAVSHRPAVIRIADQILEVRDGKVLATHHAVDPDGTRADEAKA
>NZ_CP051487|2991139:3032300|3020077_3021094_-|WP_020797747.1|DBSCAN-SWA
MTATLIRTLLALVMLLVAVIAGVAIGETRIEPGVVFQVLANKMWMAGYVLDPIDEGIVWNYRLTRALVAAACGAGLATCGVILQSLLRNPLADPYLLGISAGASTGAVLVALLGLGAGAISMSAGAFAGAVAAFTVVVLLGRASGSPGSTGQIILAGIAGSQLFNALTAFLITKSASSEQARGIMFWLLGNLSGVRWPSVWLAVPVAVAGLAVCLWHRRALDAFTFGADSAASLGIAVRPVQFLLISCAALVTAVMVSIVGSIGFVGLVIPHAARLLLGTRHTRLLPASALGGAVFLVAADVLSRTLIKGQVIPVGVITALVGAPVFALILVGRRNAR
>NZ_CP051487|2991139:3032300|2991930_2992749_-|WP_168757940.1|DBSCAN-SWA
MTRLLHISDTHFGTEQLPVMQAFETYVKAHGADLVLFSGDITQRARRGQFASAQAFINRIKGYGIPKVLTIPGNHDIPMFNLFARLFSPYGNYYKYIDSNLAPVFENDDALIICLNTTHPARRKDGKVTARQVEEVAERLQKCDPQKLRIVVAHQPFGAIVASDQRNLQIGARAALERWASSGLDLVMGGHIHLPYVLALSTQYGALSKEIWGVQAGTTLSSRLRGNAPNSFNRIHLDKLTRRVTVERWEYSALRDTFEPSIESHCDCPPGR
>NZ_CP051487|2991139:3032300|3026805_3029163_-|WP_168757960.1|DBSCAN-SWA
MSQGWARSLRRPLRAMGCACCLVVIHHAEAADLPPPPSGMEAVADAQLFLELVVNQMNTGRIVAVEQRNGRFFVPASALHETGMKLPQDIGAEVGLDTLPGLHSEYDSKAQRLLLDVPPDWLPEQFVGRSQVYPRTPALSSFGALLNYDLYLNDTDDAGTYLAAWNEVRLFDSWGTLSNTGQYRRTLSGDAINTLNNGYLRYDTTWRYSDDDRMLTYEAGDLVSGALPWSNSVRLGGVKLSRDFGVRPDLVTYPLPQFAGEAAVPSSVDLFINGYKSSSADLQPGPYTLTNIPFINGAGEAVVVTTDALGRQVSTTVPFYVTSSLLQKGLSDFSVAAGTLRQDYGLQDFSYGPGVTSGSLRYGLSDNFTLESHAEASDTLALGGVGGNVRLGNFGVLNSAVSQSRFDGQTGQQLSLGYQYSSQRYSFSWQRLQRRDQYADLTVVDSPYTTLSKRSEQATLSVNLDTWGSLGAGYFDVRAADDSRTRLLNLTWSKPLWRNTSFYLSANREIGDSNWAVQAQLVIPFDLRGSLAIGSERSKTGQSQQRVNYSRAVPTEGGVGFNLGYAKGDGPDYRQADLTWRLQSVQLQAGVYGTSDAQTRWADASGSLVWMDRQVFAANRIDDAFVVVSTDGYADIPVRYENQQVGQTDRNGHLLVPWSSAYYRGKYEIDPLNLPANVRSPNVEQRIAVRRGSGYLLEFPLSRVIAASIVLVDVQQQDLPLGSGVLHEQSGTQTVVGWDGLVYLENLQAQNDLRVTLGDGKTCHVQFAADLAQDQIPLIGPLVCR
>NZ_CP051487|2991139:3032300|2997322_2998153_-|WP_033045678.1|DBSCAN-SWA
MKSTFEVRPFTALVLAADRGPADPVAAVAGTCCKALAPVAGVPMVRRVVEALAASDRIDRIVLVGPARNLMAQDASLAQLLDCASVSWLEPANSPSASAALALARQPADSPVLVTTADHALLSPQIVDYFLAQATSGGHDFVVAVTPLDTVLAGFPGTRRTSIRLRGGPYCGSNLFAFMTEDARRLASYWQRVEHDRKHPRRVIAGALGVEGVLRYLLGRLTLEQALQQLSNRLGVSLGAVVMPFPEAAIDVDSPLDYQMVERIHAQRNQSIPSDT
>NZ_CP051487|2991139:3032300|3017933_3019268_-|WP_168757953.1|DBSCAN-SWA
MHTRSAILFALASPLALADSVQSQAKGFIQDSAWSVLNRTVYDHREYLNGARNGAARNAYKPRDERNGYAEEWAYGLMATVQSGFTQGLIGVGMDAHAYLGAQLDSGGGRAGKARLLGLDNQGHPKDAFSRGGAALKLRRSSTVLSYGEQRVKTPVFSSSDSRLLPETATGVFLTSNEFEALTLVAGHFSESTDRNASSHDQGFVVNYSNAVKGNAFDLAGVVFTPAKKLTVSAYTSRYEDTWNQHYLGSTFIQPLGETRALSINLNLYRTTDEGKSLSGRIDSTTWSLMSTYTQGPHGFSLGYQKVDANTPFDYVTRGAIFISNAVQLSDFNAPHEQSWQARYDFDASPWGLPGLSMSAAYVRGSRIDGSHVDPQGGYAYLGYGEGGKHWERDLQVRHVVQGGAAKGTTLSLQYNVHRGNTAQAELDTDQIRLAVEYPLTGRF
>NZ_CP051487|2991139:3032300|3017287_3017893_-|WP_020797744.1|DBSCAN-SWA
MILVVEGISASGKTTWCAEHGKQHVIPENGRFDNEPDRIKNPVGAATFWAERNVDRWQQTLAMEDTSSWALCDSDPLKLHYIWSLWQIGEASEPEWRVELDATRETIAQGRIGFADCYIVGRIDPQLARARAKADTTRRRSKFELHVRLQQALLTWYSAMDEVLPGRVRFGFPSKMPTVGNLDGRYSVTAFDQMIASLPGK
>NZ_CP051487|2991139:3032300|3014550_3015807_-|WP_168757951.1|DBSCAN-SWA
MTADTDSAAQCLVRRPGQIGECTGFEHSPGLSPSLTLLFSITCALAVGNVYFAQPLLDSMAQSLGVDSSMIGIVVTATQVGYALGLLFIVPLGDLVNHKRLILAQVLLSALALAAVGAAQQWLALLSAMIVMGLLAVVVQVLVAYAAALATPSQRGQAVGTVTSGIVLGILLARFTSGVIADIAGWRAVYFVSSGLMLTLAAVLWKSVPVTAVSRHQDSYLTLIRSLFTLFITEPTLRARGLLAMLIFAAFSVLWTSMVLPLSAPPLSLSHTAIGLFGLAGVAGALAARRAGRWADQGLGQRVTGISLGLLTLSWLPIAFAQTSLVALVCGVVLLDFAVQAVHVGNQSIIFAARPDAHSRMVGAYMCFYSVGSALGAAAATQVYALWGWMAVSLLGASISAAALVLWFFSSPSQDDLH
>NZ_CP051487|2991139:3032300|3004686_3005889_+|WP_083348912.1|DBSCAN-SWA
MGLFDKFGKLAAERASLCGTQIHPFGIRIDEMYSPTEGCIEGQRVILAGTNNYLGLTFDPASIKAAQRSLALEGTGTTGSRMANGSYAGHSALEEELVDFLGRSSVIVFSTGYVANLAVIGTLAGSREVVLLDADCHASIYDACKLGGAEIIRFRHNDVADLERRMVRLGERAREAIILVEGIYSMLGDQAPLREIVEVKRRLGGYLLVDEAHSFGVLGANGRGLAEELGVDSEVDILLGTFSKSLGAVGGFAACHDAQMDLLRYASRPYIFTASPAPSAIASVRTALAAIKERPELRHQLWSNARRLYQGLAESGYQLGPQASPVIAVMLESPQEGLTVWRALIERGVYVNLVLPPATPGAVTLVRCSVSAAHTPEQIDRIIEAFASLRGAMGQVTAGA
>NZ_CP051487|2991139:3032300|3030577_3031114_-|WP_168757963.1|coat|DBSCAN-SWA
MRTLASRIGLSLLGLTLASGAQAATTVTGQITSSLVLISSCQVNGGGGSTNLNFGALNFGTANSLFTTATGQVLGGGGGALSILCSAGTTPTVKVRAGAHDGQSEGGTRALYDGVANYVPYDLYTDAGHSQILAIDGVINLAASTGVAQTVNIYGQAVGKAGLPAGTYTDTISVELTF
>NZ_CP051487|2991139:3032300|3021090_3022104_-|WP_168757955.1|DBSCAN-SWA
MLLPRFFTLVTGLGLSALACASPTHYPLTIENCGSTLTFTHAPVRAVTIGQAGTEMLFALGLGDKLVGTSLWFNDVLGKYKGQNDRIERLADNEPSFESVIGKRPELVAVELEWMVGPQGAVATREQFHELQIPTYLMPSDCESKDNLVGADGTRLQPFRIDSLYRSITQLAEIFDVQARGQQLNAQLQASLAKSIAAVQGKDLTHTSALVWFSSASLDIDPYVAGHKGIPDFMLGTLGVRNVVQSDEEWPTVGWETIAKANPTFLVIARMDRRRFPADDYQRKLQFLRSDPVTRNMDAVKNNRIIILDAMAMQASLRMFDGLESLATAINRYDLPK
>NZ_CP051487|2991139:3032300|2991139_2991898_+|WP_050511669.1|holin|DBSCAN-SWA
MLSAGQGRRLLPYTTNTPKCLIEVGGQRVIEWQIDALMAAGISRITAVIGYGAEQVERVLNERYGPGVISTIYNPFFEVADNLASCWMARQIMHDDFILLNGDTLFDHPVLERLLDAPARAITLAVDKKLAYDSDDMKVQLIGDRISAIGKLIPLDHVDGESIGMMHFQAGGGPLFRSALEDSMRRPEALQRWYLSIIDHLAGTTGQVFAQSIEGLGWAELDFPADLRAAQALVRPWVCRKQGTAITLAEGE
>NZ_CP051487|2991139:3032300|3031134_3031665_-|WP_168757964.1|coat|DBSCAN-SWA
MTRFWKIFAVGALLLLSGVAQAAASGQIQARLTLIAGCEVTNGGNPDSPVSDFGTLDFGQQGPTWNNPIKARIGNQASGKLNVACNPSVTGFTVTIDGGTHGDGTTRRLSNGRRTIAYQLFLDASGNRSYSIGQQHNFAVTSGAQIPIPVFGSVVANTRALPAGIYTDTLTVTLDW
>NZ_CP051487|2991139:3032300|2993833_2995018_-|WP_168757941.1|DBSCAN-SWA
MKTPVYLICSCPVRLWGLTSRERVGRMLAKFPNAHLCNANDPLPAQGEVVLLREDYLYDDRVLQGLLATPEIALQDPRTGTIVAAHASVERLAHLPSLDTDAVAGLRKVVPGTVATAMQTQLRKFDPPWVAQITAANQAHLEKSLFNGSYKGVTDFITRAIWPVPARWATVWCVRLGLSPNQVTAASYVLAIAAGFLFWHGLFGAGLLAGWLMTFLDTVDGKLARVTVTSTRFGNLFDHGLDLIHPPLWYIAWGLGYEATWDSAIPLEPVLWAICLGYIAGRVCEGAFKLAAPFSLFLWRPFDSLNRLITARRNPNLLILTSLWAFDAHDTALIWVAVWTCVSTLILGVRTMSALVLKHRGQPPQPWLSRIDMSAERDRLIVRMFAPRSGLNDA
>NZ_CP051487|2991139:3032300|3024697_3025630_-|WP_168757958.1|DBSCAN-SWA
MWMKHKLCIARLARVASASLIMVATTAVAEDLEPRSYANTPVGINFLLLGYSDLHGNVTANPSVPLQNAKLHIKTVVFAFARSLDVWGRSGKFDIVVPEARLTGSALFAGEPRERNVTGLIDPRLRFSVNLWGAPAMSLAEFPSYQQDVIIGASLAITAPLGQYDSSRLVNLGNNRWSFKPELGVSKRLGPVTLELSAAGTFYTDNNQYLGDRTFSQNPIYQAQVHLIYAFSNGVWASLDGTYFAGGSTSVDGIGNHDFQENTRYGGTLSLPLNRNNSLKLFASEGAHTRTGSEYDAVGIVWQYRFGGGL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050511669.1|2991139_2991898_+|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_168757940.1|2991930_2992749_-	metallophosphoesterase	NA	NA	NA	NA
WP_033045682.1|2992878_2993841_-	hypothetical protein	NA	NA	NA	NA
WP_168757941.1|2993833_2995018_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_168757942.1|2995097_2996180_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_168759169.1|2996176_2997250_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_033045678.1|2997322_2998153_-	NTP transferase domain-containing protein	NA	NA	NA	NA
WP_020801069.1|2998136_2999279_-	hypothetical protein	NA	NA	NA	NA
WP_168757943.1|3001759_3003490_+	fatty acyl-AMP ligase	NA	NA	NA	NA
WP_168757944.1|3003486_3004404_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_168757945.1|3004439_3004700_+	acyl carrier protein	NA	NA	NA	NA
WP_083348912.1|3004686_3005889_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	D2TEZ5	Emiliania_huxleyi_virus	1.3e-41	32.8
WP_168757946.1|3005947_3007675_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.7e-29	26.8
WP_033043596.1|3007850_3008627_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_168757947.1|3008680_3010792_-	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_168757948.1|3010967_3012770_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_168757949.1|3013033_3013879_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_168757950.1|3013939_3014431_-	DUF417 family protein	NA	NA	NA	NA
WP_168757951.1|3014550_3015807_-	MFS transporter	NA	NA	NA	NA
WP_168757952.1|3015905_3016364_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_033043439.1|3016412_3016808_-	GFA family protein	NA	NA	NA	NA
WP_020797743.1|3016839_3017235_-	hypothetical protein	NA	NA	NA	NA
WP_020797744.1|3017287_3017893_-	hypothetical protein	NA	NA	NA	NA
WP_168757953.1|3017933_3019268_-	OprD family porin	NA	NA	NA	NA
WP_168757954.1|3019289_3020081_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.1e-11	32.3
WP_020797747.1|3020077_3021094_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	8.2e-08	20.9
WP_168757955.1|3021090_3022104_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_168757956.1|3022478_3023645_-	DUF1624 domain-containing protein	NA	NA	NA	NA
WP_168757957.1|3023836_3024205_-	hypothetical protein	NA	NA	NA	NA
WP_168757958.1|3024697_3025630_-	transporter	NA	NA	NA	NA
WP_168757959.1|3025846_3026809_-|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_168757960.1|3026805_3029163_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_168757961.1|3029239_3030028_-	molecular chaperone	NA	NA	NA	NA
WP_168757962.1|3030072_3030573_-|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_168757963.1|3030577_3031114_-|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_168757964.1|3031134_3031665_-|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_168757965.1|3031772_3032300_-|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP051487|4462729:4469005|DBSCAN-SWA
CATGAAGTTCGCCATCGCCGTATTTTCCGCCGCCCATGCGCCCTCTTCGCGCCGCGCCTTGCTGTTCGCACAGGCGCTGCTTGCCGGCGGGCATGAGATTGTCCGGCTGTTTTTCTACCAGGATGGCGTGTACAACGCCTCCAGCAGCGTGGTCACACCCCAGGACGAGCTGGATGTGCCCCGGCAATGGCGCGCCTTCGTCAGCGAAAACCAACTCGATGGCGTGGTGTGCATCGCCGCCGCCTTGCGCCGTGGCGTGTTGAACGAGGAGGAAGCCAGGCGCTATCAGCGCGAGGCTGTCGCCGTCGGCGCGCCGTGGGAATTGTCCGGGCTGGGGCAGTTGCATGACGCGGTGCAGGATGCCGACCGCCTGATCTGCTTCGGAGGTGCGTGAAATGGCCAAGTCCTTGCTGATCATCAGCCGCCAGTCGCCCTGGTCCGGTCCAGGCGCACGCGAGGCGCTGGACATCGTGCTGGCGGGAGGCGCCTTCGATCTGCCGATCGGCCTGCTGTTTCTCGACGACGGCGTGTTCCAGCTCGCCCCTCATCAGCACGCCAAGGCCCTGCAACAGAAAGACCTGAGCGCCAACCTGCAGGCGCTGCCGATGTTCGGCGTCGAAGAACTGTTTGTCTGTGCCGACAGCGCTGCCGAACGTGGCCTGGACCCAGGTGCCCTGGTACTGGAGGAAGCCCGCGTGTTGGCCGCCCACGAAATCACCGCACTCATTGACCATTACGACCAGGTGATCACCCTCTGATGTCGACTTTGCATGTGTTGTCTCATTCCCCGTTCGGCGACGACCGCCTGAACAGCTGCCTGCGCATAATCGGCGCCAACGACGCATTGCTGCTGTGCGGTGACGCCGCCTATGCCCTGCAGCCGGGCAGCGCCCCTTTCACGGCGCTGAGTGCGCGCGGCCTGGCCCTCTACGTGCTGGCCGAAGATGCCCAGGCCCGGGCTATCGAAGTTCCGGGTTGGGCTACGGCTGTCGATTATCCGGCCTTCGTCGAACTGTCGATCCACCACGCCAAGGTCAACAGCTGGTTATGAATGTATTGACGGTCGGCGCGCGCGCCATCGAGCTGGACAAGGACGGTTTTCTGCTGGAGCTCAGTGACTGGTCGGCAGACGTCGCCAGTGCCCTGGCCGCCGCCGAAGACATCGAGTTGAGCCCGGAGCACTGGGAAATCCTCGAACTGTTGCGCAGCTTCTACGCCGAATTCCAGCTGTCGCCGGCGACCCGGCCGCTGATCAAGTACACCGCATTGAAACTCGGCCCGGACAAAGGCAACAGCCTGCACCTGAACCGACTGTTCAAAGGCACCCCTGCCAAACTCGCCGCGAAACTGGCGGGCCTGCCCAAACCGACGAATTGCTTATGACCGACTACCCAGCGTTGACCCTCGAAACGCCTGCCGAGCACCCGTTCGCCCAATTCGTGCGCATCCTCGGCAAAGGCAAGCGTGGTGCCCGTGACCTGACGCGTGAAGAAGCCCGCGCCGCCATGGGCATGGTGCTTGACGACCAGGTCGAGGACACCCAGCTCGGCGCGTTCCTGATGCTGTTGCGCCACAAGGAAGAAAGCGCGCAGGAAATGGCCGGTTTTACCGAGGCCCTGCGCGAGCGCTTGCAAGCGCCGGCACTGGCGGTCGACCTCGACTGGCCGACCTATGCCGGCAAGAAGCGTCACCTGCCGTGGTACCTGCTGGCCGCCAAGTGCCTGGCGCAGAACGGTGTGCGGGTGTTCATGCACGGTGGCGGCGCGCACACCGCCGGTCGACTCTACAGCGAACAACTGCTCGATGAACTGAACATCCCGTTGTGCCGCGACTGGCAGCAGGTCGGCACAGCGCTGGACAACGGCGGCCTGGCCTTCATGCCGTTGGTGGATTGGGCGCCGCAACTGCAGCGCATGATCGACCTGCGCAACACCCTCGGCCTGCGCTCGCCGATCCACTCCCTGGCGCGCATTCTCAATCCGTTGGGCGCCCGTTGCGGCCTGCAAAGCATCTTCCACCCCGGCTATCAGGCGGTGCATCGCGATGCCAGCGGCTTGCTCGGCGACACTGCGATCGTGGTCAAGGGCGATGGCGGCGAGATCGAGATCAACCCCGACGCCGACAGCCACTTGTACGGCACCACCGGTGGCGAGAGCTGGGATGAGGAGTGGCCGCAACTGTCGAGCCAGCGCCACGTCAAACCCGCCAGCCTGGAACCGGCGCACCTCAAGGCGGTATGGCGCGGCGATGTGGTGGACAGCTACCCGCAAATGGCCCTGATCTCGACCATGGCCCTGGCGCTGCGCGGCCTCGGCCATAGCCGCGAGCAAGCGTTCGAGACTGCCCAGCAGTACTGGGATGCGCGTGACAAATCGATTTAATCGATCATAACCTATTAAGCTTTGCGCTTTTTTATCGAACCTATGAGCTTAGACTCCTCTCCAACGCTTATCGATAGAGGAGACTTGGACATGGGTTTGTTAGTTGAAGGTCGCTGGCAGGACAAGTGGTACGAAAGCAAGGACGGCACGTTCCAGCGCGAACAGGCGCAGCGTCGCAACTGGGTCACCGCTGACGGCCAACCGGGCCCCAGTGGTGTCGGTGGTTTCGCCGCTACGCCAGGGCGCTATCACCTCTACGTGTCGCTCGCCTGTCCCTGGGCCCATCGCACGCTGATCCTACGCAAACTCAAGGGCCTGGAAAGCCTCATCGACGTGTCGGTGGTCAGCTACCTGATGCTGGAGAACGGTTGGACGTTCGACAAGTCCCACGGCTCCACCGGCGACAAACTCGATCACTTTGACTTCATGCACCAGCGCTACACCGCCGACACCGCAGACTACACCGGCCGCGTCACGGTGCCGGTGCTTTGGGACAAACAACAGAAACGCATCGTCAACAATGAATCGGCGGAAATCATCCGCATGTTCAATGGCGCCTTCGATGAACTGACCGGCAATGACCTGGATTTCTATCCGGCACCGCTGCGCGGCGAGATCGACGCGCTGAACGAGCGGATCTATCCGGCCGTGAACAACGGCGTATACCGCGCCGGGTTTGCTACCTCGCAAACCGCCTATGAGGAGGCCTTCGATGAACTGTTCGCAGAACTGGATCGCCTGGAGCAGCTGTTAAGTGCCAATCGCTACCTGACCGGCGAGTACCTGACTGAAGCGGACATCCGCCTGTTCACTACGCTGATTCGATTCGACGCGGTCTATTACGGTCACTTCAAGTGCAACCTGCGACGCATTGCCGACTATCCGAACCTGTCGAATTGGCTGTGGGAGATTTACCAGTGGCCAGGGATTGCCGAGACGGTGGATTTCGAACACATCAAAAACCACTACTACGGCAGTCACAAGACCATCAACCCGACGGGGATCGTGCCGAAAGGGCCGCAGCAGGATTTCACCACGGCCCATGATCGGGAGCGGCTGAGCGGGAAAGGGGTTTGGCGCAGGGCCTGAAGGCTGATCGTTCCCATGCTCCGCGTGGGAATGCATCCCGTGACGCTCCGCGTCACAGCGTTAGAAGCGGAACGCAGAGCGTCCCTGGCGGCGTTCCCACGCAGAGCGTGGGAACGATCGGTTGCAGAGATTCAGACTTGTGATTGAGCCCCTTCAAACCACGCCAGTTTCTCGCGCAGTTGCACCACTTCTCCCACGATCACCAGCGTCGGCGCATGCACTTCATGCTCCGCCACCAGCCGTGGCAGGTCCGCCAGGGTGCCGGTAAACACCCGCTGATTGACCGTAGTGCCCTGCTGGATCAGTGCCGCCGGGGTATCCGCCCCGCGACCGTGCTTGATCAACTGCTCACAGATGCTCGGCAAGCCCACCAGTCCCATGTAGAACACCAGTGTTTGCGCTGGCGCGACCAGGTCGGCCCACGGCAGATCGGTGGAGCCGTCCTTCAGGTGACCGGTAATGAACCGCACCGACTGGGCGTAATCGCGGTGTGTCAGCGGAATCCCGGCATAAGCAGCACAACCGCTGGCCGCCGTGATGCCCGGTACGACCTGGAACGGGATGCCATGGGCCGCCAATTCTTCGATCTCTTCACCGCCACGCCCGAAGATGAACGGATCGCCGCCCTTCAACCGCACCACACGCTTGCCTTGCTTCGCCAGGTCGACCAGTTGCTGGTTGATCTGGTCCTGCGGCACGGCGTGATCGGCGCGGCGCTTGCCGACATACACGCGCTCGGCATCACGACGGCACAACTCGATAATCGCTGGTGCCACCAAGCGGTCGTACAACACCACGTCGGCTTGCTGCATCAGGCGCAAGGCGCGGAACGTCAGCAGGTCCGGATCACCGGGACCGGCGCCCACCAGATACACCTCACCGGTGGCCACCGGCGCCTCTCCAGCAATCTTCGCCTGCAGCAATCGCTCGGCTTCCCCGCCCTGCCCGGCCAGTTGCCGGTCGGCAATCGGGCCCTGGAACACGTCTTCCCAGAACGCACGACGTTGCTGCACGTCCGGGAACAGCTTTTTCACCTGGTGACGGAAACGTGCCGCCAGGCCAGCCAGTTGACCATAGGTCGAAGGAATCCAGGTTTCGATCTTGGCGCGGATCAATCGCGCCAGCACCGGCGCGTCGCCACCACTGGACACGGCAATGATCAGCGGCGAACGGTCGACAATGGCCGGGAAGATCACGCTGCACAAGGCCGGCGCGTCCACCACATTGACCGGCACGCAACGCCGATGGGCATCGGCAGACACCTGTGCATTGAGCGTTTCGTCGTCGGTGGCTGCAATGATCAGCGCGCAACCGTCCAGGTCCGACTCGAGGTAACCGCGCGTCAGGCACTCGCCGGCGCTGGCGCTGACCAGCTCGCGCAGCTGGGTTTCGATTTCAGGTGCGACCACCCGCAGCAGCGCACCGGCATCGGCCAGCAGGCGGGATTTGCGCAAGGCAATTTCCCCCCCGCCGACGACCAACACACGACTGCCGCGAAGGTTATGGAACAGCGGCAGATAGTTCATTTAGCCGATGACCTCAAGGCCACCCATGTAAGGCTTGAGCACCTCAGGCACACGGATCGAACCGTCGGCCTGCTGGTAGTTTTCCAGCACCGCCACCAGGGTACGACCGACCGCCAGGCCGGAACCGTTCAGGGTGTGTACCAGTTCCGGCTTGCCGGTTTCCGGGTTACGGAAACGCGCTTGCATACGACGGGCCTGGAAATCGCCGCAGTTGGAGCACGACGAGATTTCACGATATTTGTCCTGGCTCGGAATCCACACTTCCAGGTCGTAGGTCTTGACCGCGCTGAAGCCCATGTCGCCGGTGCACAGCGCGATGGTGCGGTAAGGCAACTCCAGCAGTTGCAGGACTTTCTCGGCGTTGGCGGTCAGGCCCTCAAGCGCTTCCATCGAAGTCGACGGCTCGACGATCTGGACCATCTCGACCTTGTCGAACTGATGCTGGCGGATCATGCCGCGGGTATCGCGACCCGACGCACCGGCTTCACTGCGGAAGCACGGCGTGTGGGCAACGAACTTGATCGGCAGCAGTTTCGAATCGACGATTTCGCCGGCGACAATGTTGGTCAGCGACACTTCGGCGGTCGGGATCAGGTACAGGTCGGCTTCGCCTTCGCGCGCGATCTTGAACAGATCTTCTTCGAACTTCGGCAGTTGACCAGTGCCCTGCAGCGCCGGAGCCTGGACCAGATAAGGCGTGTAGGCCTCTTCGTAGCCGTGCTCGGTAACGTGCAGGTTGATCATGAACTGCGCCAGGGCGCGGTGCAGGCGCGCGATCGGGCCGCGCAGCAGGGCGAAACGAGCGCCGGACAGCTTGGCAGCGGTCTCGAAGTCGAGCCAGCCAAATTTTTCGCCCAGGGCGACGTGGTCCTGTACCGGGAAATCGAACGCGGTCGGCGTGCCCCAGCGGCGCACTTCGACGTTGCCGTCTTCGTCGTCGCCAATCGGCACCGATTCGTGTGGCAAGTTGGGAATGCCGAGCACGATCGAGTCCAGCTCGGTCTGGATCGAGTCCAGCTCGGTTTTACCGGCACTCAACTCGCCCGCCATGCGCTCGACGTCTGCCATCAACGGGGCGATGTCTTCGCCGCGCTGCTTGGCTTGACCGATGGATTTGGAGCGCGCGTTACGTTCAGCCTGCAGTGCTTCGGTGCGGGTCTGGACGGTCTTGCGCTGTTCTTCCAGCGCTTCGATGCGCGCGACATCCAGGGTAAAGCCACGGGATGCCAGGCGGTCCGCTACGTCCTGAAGGTTGCTACGTAACAGTTTGGAATCGAGCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP051487|4462729:4469005|4465199_4466198_+|WP_168758534.1|DBSCAN-SWA
MGLLVEGRWQDKWYESKDGTFQREQAQRRNWVTADGQPGPSGVGGFAATPGRYHLYVSLACPWAHRTLILRKLKGLESLIDVSVVSYLMLENGWTFDKSHGSTGDKLDHFDFMHQRYTADTADYTGRVTVPVLWDKQQKRIVNNESAEIIRMFNGAFDELTGNDLDFYPAPLRGEIDALNERIYPAVNNGVYRAGFATSQTAYEEAFDELFAELDRLEQLLSANRYLTGEYLTEADIRLFTTLIRFDAVYYGHFKCNLRRIADYPNLSNWLWEIYQWPGIAETVDFEHIKNHYYGSHKTINPTGIVPKGPQQDFTTAHDRERLSGKGVWRRA
>NZ_CP051487|4462729:4469005|4466329_4467724_-|WP_168758535.1|DBSCAN-SWA
MNYLPLFHNLRGSRVLVVGGGEIALRKSRLLADAGALLRVVAPEIETQLRELVSASAGECLTRGYLESDLDGCALIIAATDDETLNAQVSADAHRRCVPVNVVDAPALCSVIFPAIVDRSPLIIAVSSGGDAPVLARLIRAKIETWIPSTYGQLAGLAARFRHQVKKLFPDVQQRRAFWEDVFQGPIADRQLAGQGGEAERLLQAKIAGEAPVATGEVYLVGAGPGDPDLLTFRALRLMQQADVVLYDRLVAPAIIELCRRDAERVYVGKRRADHAVPQDQINQQLVDLAKQGKRVVRLKGGDPFIFGRGGEEIEELAAHGIPFQVVPGITAASGCAAYAGIPLTHRDYAQSVRFITGHLKDGSTDLPWADLVAPAQTLVFYMGLVGLPSICEQLIKHGRGADTPAALIQQGTTVNQRVFTGTLADLPRLVAEHEVHAPTLVIVGEVVQLREKLAWFEGAQSQV
>NZ_CP051487|4462729:4469005|4462729_4463122_+|WP_168759202.1|DBSCAN-SWA
MKFAIAVFSAAHAPSSRRALLFAQALLAGGHEIVRLFFYQDGVYNASSSVVTPQDELDVPRQWRAFVSENQLDGVVCIAAALRRGVLNEEEARRYQREAVAVGAPWELSGLGQLHDAVQDADRLICFGGA
>NZ_CP051487|4462729:4469005|4464107_4465109_+|WP_168758533.1|DBSCAN-SWA
MTDYPALTLETPAEHPFAQFVRILGKGKRGARDLTREEARAAMGMVLDDQVEDTQLGAFLMLLRHKEESAQEMAGFTEALRERLQAPALAVDLDWPTYAGKKRHLPWYLLAAKCLAQNGVRVFMHGGGAHTAGRLYSEQLLDELNIPLCRDWQQVGTALDNGGLAFMPLVDWAPQLQRMIDLRNTLGLRSPIHSLARILNPLGARCGLQSIFHPGYQAVHRDASGLLGDTAIVVKGDGGEIEINPDADSHLYGTTGGESWDEEWPQLSSQRHVKPASLEPAHLKAVWRGDVVDSYPQMALISTMALALRGLGHSREQAFETAQQYWDARDKSI
>NZ_CP051487|4462729:4469005|4463775_4464111_+|WP_008062047.1|DBSCAN-SWA
MNVLTVGARAIELDKDGFLLELSDWSADVASALAAAEDIELSPEHWEILELLRSFYAEFQLSPATRPLIKYTALKLGPDKGNSLHLNRLFKGTPAKLAAKLAGLPKPTNCL
>NZ_CP051487|4462729:4469005|4463123_4463486_+|WP_168758532.1|DBSCAN-SWA
MAKSLLIISRQSPWSGPGAREALDIVLAGGAFDLPIGLLFLDDGVFQLAPHQHAKALQQKDLSANLQALPMFGVEELFVCADSAAERGLDPGALVLEEARVLAAHEITALIDHYDQVITL
>NZ_CP051487|4462729:4469005|4463485_4463779_+|WP_020799593.1|DBSCAN-SWA
MSTLHVLSHSPFGDDRLNSCLRIIGANDALLLCGDAAYALQPGSAPFTALSARGLALYVLAEDAQARAIEVPGWATAVDYPAFVELSIHHAKVNSWL
>NZ_CP051487|4462729:4469005|4467724_4469005_-|WP_083349381.1|tRNA|DBSCAN-SWA
MLDSKLLRSNLQDVADRLASRGFTLDVARIEALEEQRKTVQTRTEALQAERNARSKSIGQAKQRGEDIAPLMADVERMAGELSAGKTELDSIQTELDSIVLGIPNLPHESVPIGDDEDGNVEVRRWGTPTAFDFPVQDHVALGEKFGWLDFETAAKLSGARFALLRGPIARLHRALAQFMINLHVTEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLFKIAREGEADLYLIPTAEVSLTNIVAGEIVDSKLLPIKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQIVEPSTSMEALEGLTANAEKVLQLLELPYRTIALCTGDMGFSAVKTYDLEVWIPSQDKYREISSCSNCGDFQARRMQARFRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEVLKPYMGGLEVIG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_168759202.1|4462729_4463122_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	3.8e-54	80.6
WP_168758532.1|4463123_4463486_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	9.9e-41	67.5
WP_020799593.1|4463485_4463779_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	2.8e-30	67.7
WP_008062047.1|4463775_4464111_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	2.7e-45	80.2
WP_168758533.1|4464107_4465109_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	2.5e-166	86.0
WP_168758534.1|4465199_4466198_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_168758535.1|4466329_4467724_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_083349381.1|4467724_4469005_-|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.6e-96	54.2

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NZ_CP051487|6348138:6390952|DBSCAN-SWA
ATCAACAATCCGGCTTGTCCGCCGTAAACCTGCGAGCCGGATTCACCGCCGCGCCAAACTCGCGCAAGGCCTTGGCGCCGATCAACAATGGGTAATTGAAGCTACTGCGATCGGTGAGGTTAACCTCGACCGTGCGTTTGACATTGCCCAGGCACAACTCCAGATCCACCACCGGTCGCTTGGTGGGCGCGATCACTTCGCTGTCATCTTCGTCCTCTTCGGAACGGGTCTTGATCTTGCTGATCCGCGCGACCTTGTGTTCGTAAACCTTATTGCTCGCGCCCTTGGTGGCGAGACGGAAGCGCACCCAGTCTTCGCCGTCGCGGGTGAAGGTTTCGATGTCCTTGGCCGACAGCGACGCGGTCAGGGCGCCGGTGTCCATCTTGGCCTTGAGCACTTCGCCGCCGATTTCCGGTAGCGCGATGTATTCGTAGCGACCGTACAGGGTCGGCTCGGCGGCCATGACCGGCAGGGCGATGAGTGAAAACAGTGCAAGAAGGGATTTCACGTACGGGGAGTCCTTGAGAGATGGGCAGCGCAATTTTAGACCGTTGTCGAATAGATCGTTCCCACGCAGCGCAAAGGATTGCCTCAACGTACGCTCTGCGTTCGGCCCCTGATTTGGGACGCAGCGCGTCCCGGGCTGCATTCCCACGCGGAGCATGGGAACGATCGGTGTCAGGAGGTTAGCGCGTCAAAGGTGAAACATTCGTCACCGGTGATTTGGCCTGTCGCCCGAAGCTGCTTATCATGGCGCGCCCAAACGCTTCCAAGAGTTCTTTATGCGCCGCCTGCTCACCGGCTGTTTTGTCACATTGCTGCTGTTACTTAACACCCTGGTCCTGATCGGACCCTTGATGGTGTTTGCCCTGCTCAAGCTGGTCCTGCCCGGCCGCTTTCGCGATTATGCGTCCTGGGTGGTGATGTGGATTGCCGAGACCTGGTCGGAAATCGACAAGCTGATCTTTCGCCTGTGCATTCCCACCCGATGGGATATCCGCGGCGGTGACGATCTGCGTCGTGACACTTCGTATCTGGTGATCAGCAATCATCAGTCCTGGGTCGATATCCCGGCGCTGATCCAGACGCTGAACCGACGCACACCGTTTTTCAAATTCTTCCTCAAGAAAGAACTGATCTGGGTGCCGTTCCTCGGCCTGGCATGGTGGGCGCTGGATTACCCATTCATGAAGCGCTACACCAAGGCTTTTCTGGCGAAGAACCCGGAACTGGCCGGCAAGGATCTGGAGATCACCAAACAGGCCTGCGAACTGTTCAAGCGCCAGCCCGTGACCGTGGTCAACTATCTGGAAGGCACTCGCTACACCAGCGCCAAAAGCACCCAGCAACAATCACCCTTCACTCACCTGCTCAGGCCCAAGGCCGGTGGGGTAGCCTTTGTGCTGGCAGCGATGGGCGAACAACTGGATGCCATTCTCGACGTCACCGTGGTCTATCCACAGCAAGCGATTCCGGGGTTCTGGGACTTGATCAGCGGCAACGTTCCGAGGGTCATCATTGACATCAAGACCCGCGAACTCGACCCGGCGCTTTGGCAGGGCGACTACGAAAACGATCCACTGTTTCGCGAGAAAGTCCAGAACTGGGTCAACCAGCTCTGGAACGAGAAGGACCGGCGTATCGACGATTTGCGCGCCGAGAGTCGCTGAATCAGCTACCGGTGCTGGTGCCGAATCCTGTGTCTGTGCCTGTGCCTGTGCCCCAGATGCTGCCCAAGCTACTCAGCAGGGAACCGCCGACGCCTTGTTGACCTAGGTACTGCAGGATCACCGGGGTAAACATCCCGATCATGCCGGTGTCCATGCCCAGGGCGCTGAAGGCGTTGTTCAGGTCATTGGTGTCCTTGACGTTGCCCAGGGCGTTATCCAGCCCTGCGGCCTTGCCGCTCGAACCGAGCAAACCGGCGAGCGCCCCCAACTCTCCCCCACCCGAGAGAATGTCGATGCCCGGCACGCTTTTGGCCAGCTCCGAATAATCGGTCGAACTCAGCTGATTCTTCGCCAACCCAAGCATCGCCCCGGCGCCGCCGACGGCTTGCTCTGGCGTGATGTTCAATTGGGTGAGCGCGCCCAGCAGGTCTGCTGTCTCAGAGGTCGGCGCAGCCTCCGTGGCCGCGTTGCCCTTCATGCCGGAAATGGCACTGGCCGCATCGCTCAGGCTGAATTGTGCAAAAGCCGGGCTGACCACCAGGGTCATGAGCGATGCCAGGACAAAACCGCGTGAAATCTTCATTCAGACATCCTCTTGCGTCGAGAAAAAACACCCGGCTTTCGGGCGCAAAGCTGCCGGTTTGACCGGGTAGCCGCGGGCATGTTCCTCAGGCCTGCATCCATTTCTCATCCGTTCGTCACAAAGGAGCCCTGAAGCCTGCGGCAATATCAGATTTTCAAACGAAAAAGTGATGTGCACACGCAGCTCTAAAAACGCGCATTGAGCAAATGCAACTTACAAAAAAAGGGCGATCCAAGATCGCCCTTTTTTACCTATACAGCGTTTACGCCGCGCTGAACAACTTATGCGGATCAATCACAAATTTCTTCGGCACGCCCGCATCAAACTCGCCATACCCTTCCGGCGCCTGATCCAGGCTAATCACCTGCACACCCACCACTTCAGCAATGTTGATACGGTCCCACATGATCGCCTGCATCAGCTGGCGGTTGTACTTCATGACCGGGGTCTGGCCGGTGTGGAAGCTGTGGGATTTGGCCCAGCCCAGACCAAAGCGAATGCTCAGGCTGCCCATTTTCGCGGCGGCGTCCACGGCGCCGGGGTCTTCGGTGACGTAGAGACCTGGGATACCGATCTTGCCGGCTACGCGTACTACGCCCATCAGCGAATTGAGCACGGTGGCCGGAGCTTCGTGTTTCACGCCGTCATGGCCGTGACCGCGGGCTTCGAAGCCTACGGCGTCGATGGCGCAATCCACTTCTGGCTCGCCCAGCAGTGCGGCGATTTGCTCGTGCAGTGGAGTGTCAAGGGACAGGTCGGCGATTTCGAAACCCTGGGCCTTGGCGTGGGCCAGGCGCACGGTATTGACGTCACCGACGATTACCACCGCCGCACCCAGCAGGCGAGCGGAAGCGGCCGCCGCCAAGCCGACCGGGCCAGCACCGGCGATGTATACGGTGCTGCCTGGGCCAACGCCGGCGGTCACTGCGCCGTGGTAGCCGGTCGGCAGGATGTCGGAGAGGCAGGTCAGGTCGCGGATTTTTTCCATCGCGCGATCGCGGTCCGGCAGTTTCAGCAGGTTGAAGTCGGCGTAAGGCACCATCGCGTATTCAGCCTGGCCACCGGTCCAGTCACCCATGTCGACGTAACCATAAGCACCACCGGGACGCGCCGGGTTAACGCTCAGGCACACGCCGGTATGCATTTCCTTGCAGGAACGGCAGCGCCCGCAAGCCACGTTGAACGGAACAGACACCAGGTCGCCGATCTGCAGGTTCTCGACGTCGCTGCCCTTCTCGATCACTTCACCGGTGATCTCGTGACCCAGGACCAGGCCGGTTTGCGCAGTGGTACGGCCGCGCACCATGTGCTGGTCGGAACCACAGATATTGGTGGAAACCACGCGCAGGATGACGGCGTGGTTGATTTTCCTGCCGCGCGGGTCCTGCATTTTCGGATAGTCGATTTTCTGTACTTCGACCTTGCCAGCGCCGAGATACACCACACCACGATTGCCAGACATGCTTTCACCTCGCTGTTGTTTTTATGGAACCGCGTTGCCCAGGCAGGCAGCGCGTTAATTGCTCGGGTACAGATGCTGTTTCTTGTGTTGCCTGTTATGGCCTCTTCGCTGGCAAGCCAGCTCCCACAGTGATCCGGGATAAATATCGGATGTGTGAACGACACAAAACCCTGTGGGAGCGGGCTTGCCCGCGATAGCGGTCTAAAGAACGACGGTTCTATTGGCGTTCAAAAACACTCTTCTCTCAATGTGATAACCGACCGCCCGCGCCAGGGTCAGCCCTTCGATATCGCGCCCCTTGGCGATCAGGTCTTCCGGGTAATGACTGTGATCCACCACCTCGACGCCTTGGGCGATGATCGGTCCTTCGTCCAGGTCGTTGTTGATGTAGTGCGCCGTGGCACCGACCAGTTTCACGCCTTTGTTGTAGGCCTGGTGATAGGGTTTGGCACCCTTGAAACCCGGCAGCAGGGAGTGGTGGATGTTGATCGCCCTGCCGTCGAGCTTGCGGCACAGCTCCGGCGACAGCACCTGCATGTAGCGGGCAAGGATCACCAACTCGGCACCGGACTCCTCGATCACCTGCAAGACCTGACGCTCTTGGGATGGTTTGTCGTTCGGGTCCAGCGGGAAATGGTAGTACGGGATCTGGTGCCAGTCGGCCAGCGGCTTGAGGTCCGGGTGGTTGGAGACCACGGCGACTACGTCCATCGACAATTGGCCGATGCGTTGGCGGTAGAGCAGGTCGTTGAGGCAGTGATCGGCCTTGGAGACCATGATCACCACTTTAGGCCGGTAATGCGGCGGCGTCAGCTCGAAGACCATGCCGAAAGATGCACCGCGTTCAGCGAGGCCTGCGCGAAACGACTGTTCGTCGAAACCCTCCGGCTGGCGGAACTCCACCCGAATGAAGAAACGGCCCGAGAGCCGGTCATCGAAGGAGTGGTGCTCGGTGACGTAACAGCCCTGCTCGAACAGAAAGCGCGTCACCGCGTCCACGGTGCCGAGCACGCTGGGGCAGTCGGCGGTCAAGATCCATGTGTCTGGGGCGCGGCTCATAGTGCGGTGACTCCTGAGGCATCGATAAACGAAAGCTGCATCTTGTGGGAGCGAGCCTGCTCGCGATGGACGTTAACGATAACGCGTATTTCCTGAATCAACGCGTTGCCCTCAAGTTCATCGCGAGCAGGCTCGCTCCCACAGTTGATCGCCTCCATGACTGGCTCTAATCAAGCCTGGACGCTAAGCCCGTATTCGGCAGACGCATCCTGCAACCACAACCACCAGTAATCCGAGAAGCTGCGACGGATCAGCAGCTCCCAGGTGTCTTCAGCGGTGTGACGGATCACCAGTTGCGATTTGGCGAACACCGTGCCAACAGCCTTGCCCACCGGGAAGTTGTTGGGGTGCACGTCGTAGCTGGTGGACTTCATCAATACCTGGCGCACGTTCGGGCCGCTCAGTTCGAGGATCTGCTGGCCACCGCTGACGTTGACGATCTGGATGTGCAGGTCGCCCAGCGCTTTGCGCAGTTTTTGCTCGGCGGCGAATTCTTCGCCGGTCGGGACGATCAGCAGCCACTCATCCGGCCCCATCCATTGCAGGCTGGTCTCGCCTTTGACGATGACGGTCAGAGCGCCCGGCAATTCGATGCCCAGGGCCTTGTGCACGCCCGCGGCAAATGCAGCGTCGTGGCCATCACCACGGATGGTCAGGTGACCAAGGAGTTTTTTCTCACGCACGGTAACGCCGGCGTTCTTGCGACCCTTGCCCACGAGGCTGGCGAGGTCGGCGTGATGCAGCGACGACTCGGCCTTGGCCCCGTTGGTTGGGCGCTGTTGGTAAACATTGGCTGCGGTCATAAAGCACCTGTTCCTGAATTCTGTTGGCCCTGTGGAGGCTGTTCCGCCGCCTTCGCGAGCAGGCTCGCTCCCACAAGGGTTACGCAATCTCTGTGGGAGCGAGCCTGCTCGCGAAAGCGTCGGCAGGCTCACCACAGGGCCTGGGCAATTACACGTTCTGGCGTTCGCCTTTCGGATCGAAGAACACCGAAGAAACGATTTCCGCCTCGATCACGCTGCCATCCGCCAGTGGCGCGAACACACGTTCGCCCATGCGGTTCAGGCCGCCCTTGACCACGCCCATGGCAAACGAATAGCCCAGGGAGTTGTGCAGGTAGCTGGAGGTCACGTGACCGACCATGGTCATCGGGATGGCCTGCTTGGTGTTGAACACCAGCTGCGCACCTTCCGGCAGCCACTTGTTCGGATCGATCGGCTTGAGGCCGACCAGCTGCTTGCGCTGATCACGCACGCAGTCTTCACGGTTCATCCCGCGCCAGCCGATCCACGAGAACGGTTTGTTGCGACCGACACACCAGCCCATGTTCAGGTCATCTGGGGTCATCGAGCTGTCAGTGTCCTGGCCGACTATGATGAAGCCCTTCTCGGCCCGCAGCACGTGCATGGTTTCGGTGCCGTACGGCGTCAGGTTGTACTTCTTGCCCGCGTCGACGATTTTTTCCAGCACGCCCATGGCGTAGTCGGCTTGCACGTTGACCTCGTACGACAGCTCACCGGTAAACGAAATCCGGAAAATCCGCGCCGGCACGCCACCGACCTGGGCTTCTTTCCAGGTCATGAACGGGAAGGCTTCGTTGCTCAGGTCGGCGTCGGTGACTTCGCTGAGCAGCTTGCGGCTGTTCGGCCCGGACAGGGTCATGGTCGCCCAGTGATCGGTCACGGAAGTGAAGTACACCTTCAGGTCCGGCCATTCGGTCTGGTGGTAGATCTCCAGCCATTGCAGCACGCGTGCAGCGCCGCCAGTGGTGGTGGTCATCACGAAATGGTTGTCGGCGAGGCAGGCGGTTACGCCGTCGTCGAAGACCATGCCGTCTTCTTTGCACATCAGGCCGTAGCGGGCCTTGCCCACGTCGAGCTTGGTCCAGGCGTTGGTGTAGATGCGGTTGAGGAACTCGCGTGAATCCGGGCCCTGGATGTCGATCTTGCCCAGGGTCGAAGCATCCAGCAGGCCGACGCTGTCGCGCACGGCTTTGCATTCGCGCTTGACTGCCGCGTGCATGTCTTCACCGGATTTCGGGAAGTACCATGGACGTTTCCACTGGCCAACATCTTCAAACTCGGCACCATTTTTCAGGTGCCACTGATGCAGCGCGGTGTAGCGCACAGGCTCGAAAATGTGCCCACAGTGACGACCAGCCACCGCGCCGAAGGTCACCGGCGTGTAGTTCGGACGGAACATGGTGGTGCCCATCTGCGGGATGGTCACGTTCAGCGAACGGGCAGCAATGGCCAAGCCGTTGACGTTGCCGAGCTTGCCCTGATCGGTGCCGAAGCCCAGCGCGGTATAGCGCTTGACGTGCTCGACCGACTCGAAGCCCTCGCGGGTCGCCAGTTCGATGGCGGCGGCGGTGACGTCATTCTGCAGGTCGACGAATTGCTTCGGCGCCCGTGCGGTGTTCTTTTCGTGCGGCACCTGGAACAGCGCCAGCGTCGGCTCTTCCAGACGGGTCAGGGCTTTTGGCAAGGTCGCTTCGACCGCACCGAAACCGGCTTCGCTGGCAGCGCGAACACCGCCTTCAAAACCGTCAGCCAGGGAATCGCCGAGACCGTAGACGCCGTTGATGCCACCGACGCATACACGTTTCTGCGGTGCTTCGCCCGGTACGAAACCAAGTATATCTTCGCGCCAGATCGGCTTGCCGCCCAGGTGCGAGGCCAAGTGAACCACCGGGCTGTAACCGCCGGAACTAGCGACGATGTCGCAGTCGAGCCATTCACCAGGGCTGGTGACTTTGTGGCCTTTGACATCGATCGCGGCCACGCGGGCAGCGGTCACGTGCTTGGTGCCACGGGCCTCGATCACGGCGCTGCCGGTGAGGATGCGGATGCCCTTGGCGCGTGCTTCTTCCACCAGCGCACCGCGCGGGTTGCTGCGGGCGTCGGCGACGGCCACCACTTGCAGGCCGGCATCGAGCCAGTCCAGGGCCACGCGATAGGCGTGGTCGTTATTGGTCGACAGCACCAGTTTCTTGCCCGGTGCTACACCGTAGCGGCGCACATAAGTCGAGACGGCACCGGCCAGCATGTTGCCCGGCACGTCGTTGTTGCCGTAGACCAGTGGACGCTCGTGAGCGCCGGTCGCCAGCACGACACGCTTGGCGCGAACACGGTGGATGCGCTGACGTACCTGGCCAATCGGCGCGCGGTCACCGAGGTGATCGGTGAGGCGTTCGTGAATGGTCAGGAAGTTGTGGTCGTGGTAGCCGTTGACCGTGGCGCGCGGCAACAGCAGCACGTCCGGGGTGTTCTTCAGCTCGGCGATGACGCTGGCAACCCACTCGGTCGCAGGCTTGCCGTCGAGGCTTTCGCGGGAGTCGAGCAGACTGCCGCCGAACTCTTCCTGTTCGTCCGCCAGGATCACCCGGGCACCGCTGCGCGCAGCCGCCAGTGCAGCGGCCAGGCCTGCAGGGCCGGCGCCGACGATCAGCACGTCGCAGTGCTGGTTCATGTAGTCGTAGGTGTCCGGATCGTTCTCGGTCGGCGAGCGGCCAAGACCGGCTGCCTTACGAATGTACTTCTCGTAGGTCATCCAGAACGATTGCGGGTACATGAAGGTTTTGTAGTAGAAACCCGGTGGCATCAGCTTGCCGCCGACCTTGCCGAGAATCCCCATCATGTCGTTGTTCACGCTTGGCCAGCCGTTGGTGCTGGTGGCGACCAGGCCCTGGTACAGCGCTTGTTGCGTAGCGCGCACGTTCGGGATTTGCGTGGCTTCGGTGGCACCGATCTGCAGCACCGCGTTCGGCTCTTCGGCACCGGCGGCGAAAATGCCGCGCGGACGGGAATACTTGAAGCTGCGACCGATGATGTCGACGCCGTTAGCCAGCAGTGCTGCGGCCAGGGAGTCGCCTTCAAAGCCTTTGTAGCTCTGACCGTTGAAGGTGAACGTCAGGACTTTGTTGCGGTCGATCCGTCCGCCGTTGGACAGGCGATTGATCTGGCTCATACCTTCTCTCCCAGAGCCGTGGTGGCCGCTTTCGGGCTATCGGTCTTGTCGGTGAATTGTGGCTTGGTGCCGATCTTGTAGGTTTCGAGAATCTCGTAGGTCACGGTGTCGCGGGTGACGTTGAAGTATTGGCGGCAACCGGCGACGTGATCCCACAGCTCGTGGTGCAGGCCGCGAGGGTTATCGCGGAAGAACATGTAGTCGCCCCACTCCTCGTCGGTGCAGCTGTTGGGGTCCAGTGGACGCGGGATGTGCGCCTGGCCGGATGCATGGAATTCCTCTTCGGAGCGCAGTTCGCCGCAGTGAGGACAGAAGATATGCAACATGGGGATTTCTCCTGTTAGTGGGCAACCGCAGCAGCGCCGTGTTCATCGATCAACGCACCGTTGTGGAAACGGTCGATGGAGAAAGGTGCGGCCAACGGGTGCATTTCACCCTTGGCCAGGCTTGCGGCAAACACGTTGCCCGAGCCAGGTGTTGCCTTGAAGCCACCGGTACCCCAACCGCAGTTGAAGAACATGTTCGGGACCGGGGTTTTCGAAATGATCGGGCACGCATCCGGCGTGGTGTCGACGATGCCGCCCCACTGACGGTTCATGCGTACGCGGGACAAGACCGGGAACATCTCGACGATGGCCTGGATGGTGTGCTCGATCACCGGGTACGAACCACGCTGGCCATAGCCGTTGTAGCCATCGATACCGGCGCCGATCACCAGGTCGCCCTTGTCGGACTGGCTGATGTAGCCGTGTACGGCGTTGGACATGATCACGCTGTCGATAATCGGCTTGATCGGCTCGGACACCAGCGCTTGCAGCGGGTGGGATTCGATCGGCAGACGGAAACCGGCCAGCTTGGCCATGTGCCCGGAGTTACCGGCGGTCACTACGCCAACGCGCTTGGCGCCGATGAAGCCCTTGTTGGTTTCCACGCCGATGCACACGCCGTTTTCCTTGCGGAAACCGATCACTTCGGTCTGCTGGATCAGGTCCACGCCCAAGGCGTCGGCGGCACGGGCAAAGCCCCAGGCCACGGCATCGTGACGGGCCACGCCGCCGCGACGCTGGACGGTAGCGCCCATCACCGGGTAGCGGGTGTTCTTCGAGCAGTCGAGGTACGGGATCTCATCGGCCACTTGCTTGGCATCGAGCAACTCGCCGTCCACGCCGTTGAGGCGGTTGGCGCTGACCCGACGCTCGGAATCACGGATGTCCTGCAGGGTGTGGCACAGGTTGTAGACGCCACGCTGGGAGAACATCACGTTGTAGTTGAGGTCCTGGGACAGGCCTTCCCACAGTTTCATCGCGTGTTCGTACAGGTGCGCAGACTCGTCCCACAGGTAGTTGGAGCGAACGATGGTGGTGTTGCGCGCGGTGTTACCGCCACCCAGCCAGCCTTTCTCGACCACGGCCACGTTGGTGATGCCGTGCTCCTTGGCCAGGTAGTAGGCCGTGGCCAGACCGTGCCCGCCACCGCCGACGATGACTACGTCGTAGACCTTTTTAGGGGTCGGCGTGCGCCACATGCGCTGCCAGTTTTCATGGTGACTGAGAGAGTGTTTGAAGAGGCCGAAGCCCGAATAGCGTTGCATAGTCATTTACTCCAAAACCGCACTCAGCGATAAACCGGGAAGTCCGCGCACAGAGCCGACACTTGCTGCGCAACATTGGCCTCGACGTCGGCATCGCCGAGGTTGTCGAGGATGTCGCAGATCCAGCCGGCCAGCGTCACGCACTGGGTCACCTTGAAGCCGCGAGTGGTCACCGCCGGGGTGCCGATACGCAGGCCGGAGGTCACGAACGGCGACTGTGGATCGTTCGGGACAGCGTTCTTGTTCACGGTGATGTGGGCGCGACCGAGGGCTGCATCCGCCTCTTTGCCGGTGAGGCCCTGACGGATCAGGCTGACCAGGAACAGGTGGTTGTCGGTGCCGCCGGACACTACATCGTAGCCGCGTTTGATAAATACGCCGGCCATGGCCTGGGCGTTGTCGATCACTTGCTGCTGGTAGGCCTTGAAGCCTGGCTCCAGCGCTTCCTTGAAGCACACCGCCTTACCGGCGATCACGTGCATCAGCGGGCCGCCCTGGGCACCGGGGAACACTGCAGCGTTGAGTTTCTTCTCGATTTCTTCGTTGGACTTGGCCAGGATCAGCCCGCCACGTGGACCGCGCAGGGTCTTGTGGGTGGTGGTGGTGACCACGTCGGCGTAAGGCAGCGGGTTCGGGTACAGGCCGGCGGCGACCAGGCCGGCAACGTGGGCCATGTCGACGAACAGCAGCGCACCGACTTTGTCAGCGATCTGACGGAAACGTGGGAAGTCGAGGGTCTTGGAGTAGGCCGAGAAGCCGGCGACGATCATCTTCGGCTTGCACTCGACGGCCAGGCGCTCGACTTCGTCGTAGTCGATCAGGCCGGTCTTGGTGTCGATGCCGTACTGCACGGCGTTGTACAGCTTGCCCGAGGACGACACTTTCGCACCGTGGGTCAGGTGACCACCGTGGGCCAGGCTCATGCCGAGGATGGTGTCGCCGGCTTGCAGCAGCGCCAGGTACACGGCGCTGTTGGCCGAGGAACCGGAGTGCGGCTGGACGTTGGCGTAGTCGGCGCCGAACAGTTGCTTGGCGCGTTCGATGGCCAGGGCTTCAACCTTGTCCACGTGCTCGCAGCCACCGTAGTAGCGCTTGCCCGGATAGCCTTCGGCGTATTTGTTGGTCAGGCCGCTGCCTTGCGCTTCCATCACACGTTTGCTGGTGTAGTTCTCTGACGCGATCAGCTCGATGTGATCTTCCTGGCGTTGCTCCTCGGCATTCATCGCCGCCAGCAGTGCATCGTCGTAACCCTGGATCTGGTCTTGCTTGCTGAACATCGCGTCTCTCCCAGCGGCGGCACTGCGCCATTCGTCTCGGTGAGGCACTGGCTTTTCGGCAGTGCCCTTTGATAGCGATGGTATGACCGGCTTCGAGTCGTCAAATGCCTACGCGCGCCACGTAAAGGTGCGTTTACGACATGGCGGGAAATGGCAGGTCGGACACGACCCGCGAACCAACTGCAATCCCCTGTGGGAGCGAGCCTGCTCGCGAAGGCGATGAGTCAGAAACATTGAAGTCGCCTGACACTCCCTCTTCGCGAGCAGGCTCGCTCCCACAAGCTTTCCCGGGGTTATGCGAGGGCTTGGCGCAGTGCTAGCAACACCAGGAAATGCACGGGATACAGCGCATACGCCCAGCGCCGCATCGGCGGTGGTTTTACGTCACTGGCATGTCGCAACAGGAACAGCCCCAGCCATGGCGCAATCAGACAAGTGGCGATGGCCGCCATCGCCACCTCATTACCCTGTCGAACGGAGTAATAAAGCACCTGCCATTGATTGGCCGCCAGACAAACCACCCCCGGTAACAGCGCGAAATACCAGGGACGCCGGATCACCAGCAGCATCGCCAGCGGCAACATCACGCCGAAAAATCCGAACATCAGTTGTCGCGCAAACAGTGCCGCCAGCACGACGGCGCCGGCCGCGACCAGACGCGCCTGCAGGGTCCGGTCCTGCCAGCCGAGCACCACCAGCAGACCGAGTGCCAGCGTGGGCATCACATTCAACGTGTCGGGGCTGGGAATGAACATTCGGTAGGGAATTTCACTCACTGCGCTAAACATCAGTAACCAACTCAGATAGCGCCACTGTCCGCTGGTCGCCACCGCCGGCTTGCGCGTCAGATTGATCACTATCGCCAGGCAAAACCACGGGAACGCCAAGCGCCCCGGCACATACAGCCAATCGGCGGAGTAACCGACATATCGCAGGTGATCGAGCACCATGCTCAAAAGCGCCAGCCACTTGAGCAAATCCAGTGCACGGTCGCGCTGCTTTAAGTGTGTAGCCGTGTGCATAATTGCCCGACATCCTTGTAATGTTCTGACAGTGACATCCCGTGCGCTCCCCGGATGATCTTCGGTACAGTGCGCACCATCATTGACCACGAGACGCTTCACCATAAGCGTCCCGACCACGGAAGCAGGCCATGACCGATAAGAGCCAACAATTCGCCAGCGACAACTACTCCGGCATTTGCCCTGAAGCCTGGGCTGCCATGGAGCAGGCCAACCATGGCCACCAGCGCGCTTACGGCGACGACGAATGGACCGCCCGCGCGTCCGACGATTTCCGCAAATTGTTCGAAACTGACTGCGAAGTGTTCTTCGCCTTCAACGGCACTGCCGCCAACTCGCTGGCCTTGTCGTCGTTGTGCCAGAGTTACCACAGTGTGATCTGCTCGGAAACCGCCCACGTCGAAACCGACGAATGCGGCGCCCCGGAATTCTTCTCCAACGGCTCCAAGCTGCTGATCGCCCGTACCGAAAACGGCAAACTGACGCCGGAATCGATCCGCGAAGTGGCCCTCAAGCGCCAAGACATTCACTACCCCAAACCCCGCGTCGTGACCCTCACCCAGGCCACCGAAGTCGGCAGTGTCTACACCCCGGACGAAATCCGCGCCATCAGTGCCACTTGCAAGGAGCTGGGCTTGAACCTGCACATGGACGGCGCGCGGTTCTCCAACGCCTGTGCGTTCCTCGGGTGTACGCCAGCGGATCTGACCTGGAAGGCCGGTGTTGATGTGTTGTGCTTCGGCGGTACTAAAAACGGCATGGCCGTGGGCGAAGCGATTCTGTTCTTCAACCATAAGCTGGCTGAAGACTTTGATTACCGCTGCAAACAGGCTGGGCAACTGGCGTCGAAAATGCGCTTCCTCTCGGCGCCGTGGGTCGGCATCCTGGAAAACGATGCCTGGCTCAAATACGCGCGCCACGCCAACAGCTGCGCGCAATTGCTGGCTGAACTGGTGAGCGACATTCCAGGTGTAGAACTGATGTTCCCGGTGCAGGCCAATGGCGTATTCCTGCAACTGTCGGAACCGGCCATCGCCGCACTGACCGCCAAGGGCTGGCGTTTCTACACCTTCATCGGCAACGGCGGCGCACGCTTCATGTGTTCGTGGGATACCGAAGAAGAGCGTGTGCGGGAACTGGCGGCGGATATTCGCGAAGTGATGTCGCACTAATCTCACACGCCTGCCCGCCCGCGACGCACTCTCTGTAGCAGCCGCCGAGTGCAGGCTTCGCCAGCTGCTACAGATTTGGCCGTTTGTCGGCACTGGTATTTCTGACAGTACCGTCACCAGACTTCGGGCGAGTAGTTTTAGACGACCTGAAAAGGAGCCTAAGCAGTCTTTCGGGATCCACCGCAAGGCCTGTCGAGACTCGACAAGCCATAGTGTTCAACCCTGGGAGAACGAAAAATGGAAGCTGAACGCACCACGCTCAAATCTGAACCCATCGATCGGCAACGGTACTTGGAACTTGCTCAGCCAGGTAACTTTTACAAGTACCAAGGCATGACTTTCGAAGTAAAGGAGAAAACGTTTTTGAGTCTTGGTGGTGACCAGTACGAGATTGAGGTTAAAACCACACCCGTCAAGTAACTACTCTCACGCCTCTACTTCTTGTAGGAGCCGCCGAAGGCTGCTCCTACCGAAGTTGTTCGACACTCCTTTCGAATGATCTAAAACTCAATCCGCACATCCCCCTTCGGCACGCTGCAGCACGACAGGATGTACCCTTCGGCTTCGTCTTCCTCGGTGATCCCGCCGTTGTGCTCCATCTCCACTTCACCTCCCAGCTTCAGCACCTTGCATGTGCCACAGATGCCCATGCCGCAGGCTTTGGGAATCAGCAAACCGACCTTGGCCGCTGCCGCATGCACGGTTTCGCCAGGCGCCACGCGAATGCTCTTGCCGGACGAGATGAACTCCACCTGATGCAGATCCGCCACGTCGACTTCCGGTGCTTCGGCCGCTTGTTCGGCGTGTTCCACAGCATCGGCACGCGCCTCTGGCGGCGTCGCGCCGAAGGATTCCTCGTGATAACGCTTCATGTCGAATCCGGCGGCTTCCAGCAGGCGCTTCACCGCATTCATATACGGTGTCGGGCCGCAGCAAAACACTTCCCGTTCCAGGAAGTCCGGCGCCATCAATTCAAGCATTCTATGGTTGAGGTAACCGCGATAGCCGGCCCAAGGCTCACCCATACCGTGCTTCTCGCAGATCAGGTGCAGGCTGAAGTTGTCGATCCGCGACGCCATGTGTTCCAGCTCGCGGTGGTAAATGATGTCCTTGGGCGAACGGGCGCTGTGGATAAACACCATGTCGACATTGCCGTTGGTGTCGTAGAACCAGCGCGCCATGGACATGACTGGCGTGATACCAACGCCGCCGCTGAGGTAAAGCACCTTTGGCGCAGTGAAATCCATGGCGTTGAACAGCCCGACCGGCCCGTGTACCGCCAGCTCCTGGCCTTCGTGCAAGGTGTCGTGCAGCCAGTTGGAAACCTTGCCGCCCGGCACTCGCTTGATGGTCACCGAAAAGCTGTACGGCACCGACGGCGAGCTGGAAATGGTGTACGAACGCATGATCTGCTGGCCTTCGATTTCCAGCTCCAGGGTGACAAACTGCCCCGGCTTGAAGAAGAACATGATCGGCTGGTCGGCCATAAAGCAGAAGGTGCGCACATCCCAGGTTTCCTGGATGACTTTGACACAACGGACGATGTGCCGACCATTGGCCCAGGTCTGGGTGGTTACCGGGTTCAGGAAGCTGTTGGACATGCTGATCTCCACGGCCGACTGTCGGCCTTCATGTTGGCGATTCTGCGTATAGCGCGAAACAGCCATTTACCTATCTGCGACATTCACATGCTTATCGCGACCAGCCCCCAACGACCGGGGCTTGCGCGTCGGGAACAGATTGCACCATGTCGCCCATGGATAAGGTTCTGGCCAGCGCCGGCCCCACACTCGCCCCATACCAAGACACAATCTTTACACCTTGCGTAGCACCCTTAGCAGTACACCTGATTAGCCACTTTCGCCGGCCACGCAGATGGCCTTGAGGATTAAACGATGGACGTCACTACTACCCTGAGCCTGGGCGATCCGCTGGAACCCGCACGCAAGGCCACCGCGCAGATGCTGCAAGAGCGCGAACGCACGTTCTCGCTGCCGCAGCCTTTCTACTCTGACGAGCGCCTGTTTGATATCGACATGCAGGAAATCTTCCAGAAAGAGTGGTTGATCGCCGGCATGACCTGCGAAATCCCAGCCAAGGGCAACTACCTGACCCTGCAAGTGGGCAAGAACCCGATCATCGTGATTCGTGGTGCCGAAGGCGTGGTGCATGCCTTCCATAACGTCTGCCGCCACCGTGGTTCGCGCCTGTGCACCAGCGAAAAAGGCAAGGTCGCCAAACTGGTCTGCCACTACCACCAGTGGACGTATGAACTGGACGGTCGCCTGCTGTTTGCCGGTACCGAAATGGGCGCCGACTTCGACATGAAGCAGTACGGCCTCAAGCCGGTGAACGTAAAGACCGCCGGTGGCTACATCTTCATCAGCCTGTCGGAGAATCCGCCAGCCATTGATGACTTCCTGTCGACGCTCAGCCATTACATGGAACCGTACGACATGGAAAACACCAAGGTGGCAATCACCACCACCTTGATGGAGAAAGCCAACTGGAAGCTGGTGCTGGAAAACAACCGCGAGTGCTACCACTGCAATGCGTCGCACCCGGAACTGCTGAAAACCCTGCTGGAATGGGACGACGTCACCGACCCGCGCGCCGACCAGGCGTTCAAGGACCACGTGGCCGCCTCTGCCGCTGCCTGGGAAGCCGAAAAGATCCCTTACGCCCACGCCAGCTTCGGCCTGCGTAACCGCATCGTGCGCATGCCTTTACTCAAGGGCACCGTGTCGATGACCCTGGACGGCAAACAAGGCTGCGCCAAACTCATGGGCCGCATCAAGAACCCGGATCTGGGCTCGATGCGCATCCTGCACCTGCCACACTCGTGGAACCACTGCATGGGCGACCACATCATCGTGTTCACCGTGTGGCCGATCAGCGCGCAGGAAACCATGGTCACCACCAAGTGGATCGTGCACAAGGACGCCGTTGAAGGTGTGGATTACGACGTTGACCGCATGCGGCAGGTCTGGGACGCCACCAACGACCAGGACCGTCGCCTGGCCGAAGAGAACCAGCGTGGCATCAACTCCACGGCATACCAGCCAGGTCCGTACTCCAAGACTTACGAATTCGGCGTGGTGAACTTCGTGGATTGGTACAGCGAGCGCCTGCTGAGCAACCTGGGCGCCGAGCCTGCGCCGTACCTCAAAGGCGTCCCTGTCCAGGGCTAACGCCCACGCCCCCCTGTAGGAGCGAGCATGCTCTCTCCTACAGGGACGGGTTCTCTTCCGAATTCATATCTCATATCACCTCTTTAGCACTGTACGAAATATGATCTATTGCGTTCAGAGCTATACCCTGTGTGCCTCCCAGCCTTCCGCAAACAAGTTATCCACATATCCACCCACAGCAAATGGGGACAACTGTGGAAATGCCGATAACTTTCTCCACAGAACTCAAAGAAAATCCGTGACTTATCCAGAATCAAGGTTTTTCACAGAGCCTGATCATTTATTGATCAAACCTCTATAAAGCACGAAATACGTGGCCTTCAGAGGATGGCGAACACCTTATCCACAGAAGCGCCAACAGACTTTGGGGGCAACTATTGTTCATCTGTGGAAAAGCGCTGAAAGCCGCGATTTTTGAGGGTTTACGCAGGGGATAACCGTTAAAAAGCCATCTTTGATCAATTTTTAACCAGAAGCCTGAAAGCCGCTGTTTATAAGGCCCTCAGCGGTAAGCGAACATCTTATCCACAGAAGCGCCAACAGACTTTGGGGGCAACTAGGGGCCTGCTTTGGATAAAAAAGTGTGAAAAAACCGTATCTTATGCTGGTTATAATTTGACCTAAGTCTTGCAGCTCACGGTTTTAAAGAGGTATAGCGAGGGGCGAACATGTTATCCACAGAAGAGCTAACAGGGATTGTGGGTAAACCAGGAAAAATCTTGTTAAAACGGCTTACTGTGTTTTACGGCACTGCCGAAGATAGTGGGTACAAACTGTTAACTACCCTAACAAAGCGCCACTAAAGCCAACACTATCAGGCCTGATAGGGCCGCCCGCCACCGGGCAGCCCGTTAAGGCCGATACATCAAATAGGCTTCTCCCGTGACTCGAATCATCGGATGCGGCGCAATCTGGCAGGTATCGACAACACGGAAACCATGGCGCTCATAGAACCGCCGGGCACCGGTGTTTGCGGCGTAGTCGATCAGGCTCAAGCCATTGAGCCCGAGCCGGTTGGCGCGGTCGTAGGCGTAGGCAAGGAACTGCTTGCCCAGCCCCTGGTTGCGCCAGCCTTCGTGCAGCGCCAGGCTGGAAATATAAAGGGTGTCGGGGATTTCCATCTTGGCGTACGGCGCCAGCACCGGGTCGGTCACCGGTGCCGCGAACGGATCGTGACGCATCACGTAGCTGTGCAGCATGCCAATGACCTTACCTTCAGCTTCGGCGATCAGGCAGTTCTGCCAGGAAAAATCCACATCGTCGCGGGCGTAACGCAGGGCTCCGACGTCCAACAGATCCTGCCCCGGTTCTGCTATCTGGCTCCAGATGTAATCCGCAGCGCCCTCCGATGAAATCTGGAACAAACGCGCAATCTCACGCGCATCCGCGCGAACTGCCGGACGAAATTCTACTGCCATTGACCTGCCCCCAAACGGACCGCTAGCGGACCACACCTTCTTCGATCAGCAACTTAAGGATGGCTTCAGCCCCCGCCTGTGCCGTCACGCCCTTGAGCACTTGTCCGCCACCACCACTGGCTTTCGCCGTTGCGGCTTTCATGCGATCGGCGCCGCTCTTGGCCTTGATTACCTTCAAGCGCTTCGGCCGTGGCTTGGCCGGTTGCAGGGTGGCGACCGCGAGCAATTCATCGTCGACGATTTCCACCTCATTGGCTTGCAAAACTCCGCGCCGGGCCGGACCGTAGGCGCTTTGCCGAGGCTTTGGCGCAGCGTTATCCACAGTGGCGAGAAACGGCAAGCGAACCTTCAAGCGACGCCGCTGACCGCGCGGCAGAGCCTGCAGTACCAGCGCCGAACCCCCATCAATCGACTCGACCTGCGCCAATCCCACCACCAGCGGCCAGCCAAGGCCTTCGGCCAGCAGGAACGGCAGCATGCCCGAGCCCTCGCCGGTTTCCGCCTGGCTACCGGTCAGGACCACCTGTGCCCCGGCATCGCGCAAATAAGCGGTCAACGCCGGAAGCGCATCGGCGCCCTGCGGTTGTTCAAGCACATGCAATTGTTCCAGCCCCATGCCCAGATAAGCGCGCAAGGCCGGTTCGCCAACGTCGCCGGCGTGCAGCACCTGCAAGTTATCCCCAGCCAGCTGCAAGCCCAACTCCACCGCCCGTGCATCCTGTTCCGCGCGACGTGGTCGACCGGAAGTCGGGTGGGCGCCGATGGACACCAGGCTGATGATTTTCGTGCTCATAACCCTTTCCTTCCCTTAAGCCGCATCGCGCTTGGCGTCGTTGCGGTAGGCTTCTACCGCCGCGATCAAGGCCCGAAGAATCTCCGCACTTTCGCCGATTACCGACAGGTCGGCCCGTTTGATCATGTCGCAACCCGGGTCGAGGTTGATCGCCACCACCTTGTCGCAGGCACCGATGCCCTGCAGGTGCTGGATTGCCCCGGAAATCCCCACCGCCACATAGACCCTCGCGGTGACCCAGGTGCCGGACGCGCCGACCTGACGGTCGCGCGCCATGAAGCCGTCGTCCACTGCCACCCGCGACGCGCCTTCGGTGGCGCCAAGGGCGGCGGCGGCCTGGTGGAACAAGTCCCAATCCTTGACCCCATTGCCGCCGGAGAAGATGAATTCGGCTTCGGCCATGGGAATCGCCGCCGGGTCCACTGCCACCGCCCCCAGGTCCTCGATGCGCGAGAGACTGCGGGCGACGGCTGTGGATAACTCCACCGGCAAAACTTCGTGACGAGTTTCGCTGACCGGCTCGGCGCATTCGACGGCGGCCAGGATCAACCGTGCAACCGGACGCGCCAGATCTTGCAAACCGGCACCGGCGCGACCAATACACTCCTGATCCTTGACCTGCCAGACCCGCGTGGCCGGGCGTTCGCCCAAGGCAGCGGCAAAGCGCCGACCCAATTCGCCACCGCCGCTGCGACTGTCCGGCAGCAGCCAGTGACGTGGGTTGAACTGGTTATCCACAGCCCGCAGGCCCTGGACACGTTGTTCCGGTGCATAACCGCTGAACTCTTCGCCTTCCAGCACCAGCAGGCGATCGACGCCGGCTGTGGAAAACGCGTTTTCCTTATGTTCGCCAAAGACCACGGCCAACACCGCGCCGTCGCTGCCGGCCAGTTGATGGGCCAGTCCCAGCAGATCTCGGTCGTGACTGCTCAAGCGGCCGCCGACCATGTCCGGCACCACGCAGATGAAGAATGCCGGCGCAGAGACTTGATGCAGCGGTAATTGCACTTCAACGGCGGCCGAACGTTTCGTCGTCCCGCCCTGCTGAGCGCCGCTACGGTCGATTCGCTTGATGCCGTTAGGGCCGATGAAACCGATGCCGTGCGGGTTCTTGCGAATGACGCCGTTAGGCCCCATCCAACTGTGCTGCGCCGGTTGCATGGCGGCGTGCAGAGGGTGCAAACGATTACGGGCGATCCATTCGGCACGGGGGTCGCGGCGGATAATGTCGCTCATCAGTGCACCTCCGCGGGTTCACGTTTGGCCGGCGTAGCCGACTTTGGGGCCTGATCCTCCAGGAGCGCGTCGGCCACCAGTTCGGCAATGTCCTTGATCAACGGTCGTGGTTCGACCACACCTTCAAGCATCGCGGTGCACTGCGGGCAGCCCACGGCCACCAGTTCGGCGCCCGTCTCGCGGATGTCTTCCATGCGCATGTCGGGGATACGCTGCTTGCCCGGAATGTCGGTGATCGGCGCACCGCCGCCACCGCCGCAGCAGCGCGAGCGGAAACCGGAGCGTTGCATTTCCTTGACCTCGATGCCGAGCGCGCGCAGAACCTGGCGCGGCGCTTCGTACTCGCCGTTGTAGCGGCCGAGGTAGCACGGATCGTGATAGGTCACGCTGTCGCCCTTGTGCTGGCCAAGGTTCAGCGCGCCGGCGTCGATGATTTCCGCCATGTAGGTGCTGTGGTGCTGCACCAGGTAGTTTCCATCGAAAGCGCCGTATTCGTTTTTCAGCACGTGGAAGCTGTGCGGATCGCAGGTGACGATGCGGTTGAAGCTGTACTTGGCCAAGGTCTGGATGTTGCGCTTGGCCAGCAACTGGAAGGTTGCCTCGTCGCCCAGGCGGCGAGCCACGTCACCGCTGTCGCGCTCTTCGAGGCCAAGCACGGCGAAGTCGATTTTTGCCGCTTTCAGCACTTTGACGAACGCACGCAAGGTGCGCTGGTTGCGCATGTCGAAGGCGCCATCGCCCACCCAGAACAGCACGTCGGTGGATTTCTTTTCGCTGAGCAGATTGAGGTTCAAGTCCGCCGCCCAGTTCATCCGCCCGCCTGGCGCAAAACCGCCCGGGTTATCGGTGGCGATCAGGTTTTCCAGGACTTCGGCACCCTTGTTCGGGGTAGCGCCTTTTTCCAGGGTCAGATGGCGACGCATGTCGACGATGGCATCGACGTGCTCGATCATCATCGGGCATTCCTCGACACAGGCGCGGCAGGTGGTGCACGACCACAGGGTTTCGGCGTCCACCAGACCGTTGACGATCGGTTGATGCGGATTACCGGCGTGTTCACCGATTGGCTTGCCCGGATACGGACTGCCGGCAAATTTGGCATCGGTGCCTCCAGCCAGGCCGACGACCATGTCCTGGATCAATTTTTTCGGGTTCAACGGCTGGCCGGCGGCGAAGGCCGGGCACGCGGCTTCGCATTTACCGCACTGCACGCAGGCGTCGAAGCCGAGCAACTGGTTCCAGGTGAAATCCTTGGGTTTTTCCACGCCCAGTGGCGCGCTTGGGTCGTTCAGATCCAAGGGTTTCAGACCGGTGGAACGACCGCCGCCAAAGCGCTCGGCACGACGGTGCCAGGCCAGGTGCAGGGCACCGGCGAAGGCATGCTTCATCGGCCCGCCCCAGGTCATGCCGAAGAACAGCTCGGACACGCCCCACAGCACGCCAATCCCGAGGATCACCGCCAACAGCCAGCCGCCGAAGTTTTCCGGCAGGATACCGGCCACCGGCAGGGTCACGAGGAAGAACGACACCGAAAATGCCATCAGGCTTTTCGGCAGGCGCATCCACGGACCTTTCGACAGGCGCGCAGGTGGATTGCGCCGACGCAGGTAAACAAAGACCGCACCGACGAACATCACCGCCGACATCAACAACAATGCATAACCGAGGAAGCGGTTATGCAATCCGAAACCATGCACCAGAATTGCCAGCACGATGGACGCCACTGCGCCGCCGGCCGTCGCGACGTGGGTGTTGGCAATGTATTTGTCCCGCGCCACTACATGGTGCAGATCGACCATGTAGCGCTTGGGCATGGCGAACAGGCCGCCGATCAGATCGACCTTCGAGGCCCGGCCTCGGCGCCACATGTTTACCCGTCGCAATGCACCGAGAGCCGCGAGGCCCAGGGCAGCAAAGATCAGGATGGGAAGAAGGGTGTTGAGCATGGTGAAGCTCCCAAAGACCGCGGGGTCTCATGTGGGAGCGGGCTTGCTCGCGAATCCGGCGACGCGGTGTATCAGGTGTACCGCGTTATCGTTCTTCGCGAGCAAGCCCGCTCCCACATTGGTTCGGTGTGATTTTAGAAGTCCTTGCACAGCCGCAGCGCGTCATAGATCGCCGCATGCACGTTACGCTGGGCCACACAGTCGCCGATGCGGAACAACAGGTAGCCGTCGCCTTTCTGCTCCAGGCATGGCTGCGGCTTGATCGCGAACAAGGCTTCGACGTCGATCTGGCCTTTGTTGCGCGAGCCTTCCTTCATCGCGTAGTAGATCTCCTCGTCCGGACGCACGCCGTTCTCGATGACCACCTGGTCCACCACCCGCTCCTCTTTGGCGCCGGTGTATTCGTTTTCCAGCACCGCTATCAGCTTGTCGCCTTCGCGGTAGACCTTCTCCAGCATCATGTCGCCAGTCATGATCACTTCTTTCGGATACATGCTGCGGTAGTAGGTCGGGAACGACGTACCGCCAATGGCCACGCCTGGCTTGATGTCATCGGTGACAATCTCGACCTGGCTGCCCTTGTCGGCGAGGAAGTCGGCAGTCGACATGCCGGTAAACTCGCAAATGGTGTCGTAGACCAGCACGTTCTTGGCGGGTGCAACCTTGCCGTCGAGAATGTCCCAGCTGCTGACCACCAGGCCTTCAGCCGCGCCCCAGTGCTCGTTCTGCTCGATGAACGGATGACCGCCGACGGCCAGCACCACCACATCCGGACGCAGGTCCATGATGGTCGGCGCATCCGCCGCGGTGCCCAGACGCAGGTCGACTTTCAACCGCGCCAGCTCCAGCTGATACCAGCGGGTGATACCGGCGATCTGGTCACGCTGCGGCGCTTTCGACGCCGTGGTGATCTGGCCACCGATAAAGTCCTTTTTCTCGAACAGGGTTACGTCGTGGCCGCGCTCGGCAGCCACACGAGCGGCTTCCATCCCGGCAGGACCGGCACCGACCACCACCACTTTGCGTTTAACGCCGGTGGTTTTTTCGATGATGTGCGGCAGACCCATGTATTCACGGGAAGTCGCGGCGTTCTGGATGCACAGCACGTCCAGGCCCTGGTACTGGCGGTCGATGCAGTAGTTGGCACCGACACACTGCTTGATCTGGTCGATCTGGCCCATCTTGATCTTGGCGATCAGGTGCGGGTCGGCAATGTGCGCGCGGGTCATGCCGACCATGTCGACGTAACCGCCTTCCAGGATACGGGTGGCCTGGTTCGGGTCCTTGATGTTCTGCGCATGCAGCACCGGAACCTTGACCACTTCCTTGATACCGGCGGCCAAATGCAGGAACGGCTCAGGTGGATAACTCATGTTCGGAATCACGTTGGCCAGGGTGTTGTGGGTGTCGCAACCCGAGCCCACGACGCCGATGAAATCGAGCATGCCGGTGTCGTCGTAATACTTGGCGATCTGCTTCATGTCTTCATGGGACAGGCCATCCGGGTGGAACTCGTCACCGCAGATACGCATGCCCACGCAGAAATCGTCACCGACCTCCGCGCGCACCGCTTTCAACACTTCCAGGCCGAATTTCATGCGGCCTTCGAAGGTGCCACCCCATTCGTCGGTACGCTTGTTGACCCGCGGGCTCCAGAACTGGTCGATCATGTGCTGGTGCACCGCCGACAATTCCACGCCGTCCAGGCCACCGGCCTTGGCGCGACGCGCAGCTTGCGCGTAGTTGCCGATCACCCGCCAGATTTCTTCCGGCTCGATGGTCTTGCAGGTGGCGCGGTGCACCGGCTCGCGTACGCCGGACGGCGACATCAGCGTCGGCCAGTTGAAGCCGTCCCAACGCGAGCGACGGCCCATGTGGGTAATCTGGATCATGATCTTGGCGCCGTGCTTGTGCATGGCGTCCGCAAGATTCTGGAAGTGCGGGATGATGCGGTCGGTGGACAGGTTCACCGAGCTCCACCACTCCTGCGGGCTGTCGATGGCGACGACGGACGAACCGCCACAGATCGCCAGGCCGATCCCGCCCTTGGCCTTCTCTTCGTAATACTTGACGTACCGGTCGGTGGTCATGCCGCCGTCGGTCGCATAGACCTCGGCGTGTGCAGTGCTGAGCACGCGGTTACGGATGGTCAGTTTGCCGATCTGGATCGGCTGGAACATTGCTTCGAAAGCCATGGCGGGTTCCTCGACTTACAACGGCTTGACGGTGAACAAGCCGTCTTCGTGGCCCTCTTCGGAGCCACCGTAGACTTGTTCGGCCACGGTGCGGATCTTGCTGCCACGAGCGGCGAGGATCTGGTCCATCGCGCCGGCAAACCAACCGGTGAACATGTAGTCGACCTTGCGCCCGACCTTGCCGTACACGTAGACGAATGCCGAGTGTTCAAGCTTGACGCTGCAGGTGCCTTTGTCGAGGTCGATGTCCTGGATCTTGAACAGGCCCCAGCCGCGCTGCGACAGGCGCTTCATGTAGTGCTCGAACACCGCAACGCCTTCCAGGCCATGGCATTCGGCTTCTTTTTCACACCAGTGCCAGGCGGACTTGTAGCCGGCCTTGTAGAGAATCTCGGCGTAAGCTTCGGCGCCCAGCACTTCCTCGATGCCCATGTGGTTGTTGACGAAGAAATGACGGGGCACATACAGCATCGGCAGGGCGTCGGACGTCCAGACACCGGTTTCGCTGTCGACTTCGATAGGCAATTGCGGGGCGATCTTGGCCATGGAAACTTAACTCCAGAAAAATTTTGTTGTTGCCTGCGGCGCGGACGGCCGCAGGAAAGGATTCAGAAGAGCGGTGGCTTATTCGCCCCAGACATCTTTCAAGACGTTCACCCAGTTCTCGCCCATGATCTTGCGCACCACGCGCTCGGAATGGCCGCGCTTTAGCAGGGTTTCGGTGAGGTTCGGGAACTCGCCGACGGTGCGGATGCCCAGCGGGTTGATGATCTTGCCGAAGCTGGTCAGGCGGCGGGCATAGCCCTTGTCGTGGGTCAGGTACTCGAAGAAGTCCTGGCCGTGACCCTGGGTGAAGTCGGTGCCGATACCGATCGAATCTTCACCGACGATGTTCAGGGTGTATTCGATGGCTTCGGCGTAGTCGTCGATGGTCGAATCGATGCCCTTGGCCAGGAATGGCGCGAACATGGTCACACCGACGAAACCGCCGTGGTCGGCAATGAACTTCAGTTCTTCATCGGACTTGTTGCGCGGGTGCTCCTTGAGGCCCGACGGCAGGCAGTGGGAGTAGCACACCGGCTTTTTCGATTCGAGGATGACTTCTTCGGACGTCTTGGAACCGACGTGGGACAGGTCGCACATGACGCCTACGCGGTTCATCTCGGCTACGATTTCACGACCGAAGCCCGACAGGCCGCCGTCACGCTCGTAGCAACCGGTGCCGACCAGGTTCTGGGTGTTGTAGCACATCTGCACAATACCGACGCCCAGCTGCTTGAACACTTCGACATAGCCGATCTGGTCTTCAAACGCATGGGCATTCTGGAAACCGAAGAGGATGCCGGTCTTGCCCTGCTCCTTGGCCTTGCGGATGTCGGCGGTGGTGCGCACCGGAATCACCAGGTCGCTGTTCTCGCGGATCAGCTTCTGGCTGGCGGCGATGTTGTTGACGGTGGCCTGGAAGCCCTCCCATACCGACACGGTGCAGTTGGCTGCGGTCAAACCGCCCTTGCGCATGTCTTCGAACAGTTCACGGTTCCACTTGGCAATAATCAGCCCGTCGATAACGATGCTGTCGGCGTGCAATTCGGCTGGGCTCATCAGGCTGTCCCCTTGTTAGCGATTCATGCGCCGAATCGTCTGTCGGCGCTTTGGGGCCAGCATATGCCTCGGTGCATTGGTAGCCGGGTGCAAAAACGACAGGGGAATTGCCGAAAGCGTCAATCCGCGACAAAGGGTCGTCGCAAGGCACAATTGCCGACCTGTTCAAGGCAATCCGCTTGGGCCAGAATTCGCCACATCTCTTGATGCTTCACTGGATGGGAGCGGCAACCACATGAAATTCATCGTCCTGGCCTTGGCACTGATTGCGACCGGCGTACACGCCGCCGAGGAGTCTGAAGACACCCCCTGCGACAAAGTCGAAAACGACGTACAGACCCTGGAATGCTCCGCCTTCAGCAAAACCACCGCCGAAGACTTGCTGAGCGAAAACTACAAAAGCCTGAACGAACGCATGCAGTCGCTCTACGGCAAGAACCCGTCGCAATTGGCCGAGATCACCGCCAAGATCAAGGCCGCCCAGCAACAATGGCTGAAAACCCGCGACGCTGACTGCGCCATCGAAGCCTTCCCGGCCACCGCCGGCAGCAAGGCATTCACTATTGCGCAGAATGATTGCGTGGCGCGGATGAGTGACGAGCGGTCGGAGTTTTTGGAGACGATTGGGCAGGAGTAACGCCTGCTATTCAACTGGAGCTGTAAGCTTCACGCCTTCAGCCAGAAAAGGGATTCACCATGAAAGTCTGCGGCATCGAAATCAAAGGCAGCGAAGCGATCATCGCCGTGGCAGCTCTCGACGGTTCCACGCTGAGCCATGTCGCGCTTGCGACCAAGAAAATCGCCCTGGAGGATGACGACGAAGCCGCCAATGTCAAAGTGTTTGCCGCTCAGGTCGCATCCTTTGTTCGCGAGAACTCGATAGATCGAATCGTGATCAAGAAGCGCAGCAAGAAAGGTGAGTTTGCCGGTGGGCCGACCACGTTCAAGATCGAGGGCGTTTTCCAGTTGCTGGAGAATTGCGAGGTGACGCTGCTGTCGCCGCAGACGATCAATGCACAGGCCAAGAAGCATGGTTTTGAGCCGCCGGAGACGCTGAACAAGTATCAGCATGAGGCGTACAAGGCTGCCTGCTCGGCACTTCTGAAGAAATAAGTTGCCCATTGTGGGAGCGAGCAGGCTCGCTCCCACAGGTTTTCGGGGTGGTTATGCTTTGGCGGTACGCCGATCCTCCCGCGGGCACCGCTCGAACTTCGCCCGATAACTGCGGGTGAAATACGACGGCGATTCAAACCCGCAGGCAATACTCACCTCCAACACACTCATATCGGTCTGGCGCAGCAGTTGCCGGGCTTTCTCCAGCCTCAGGCGCAGGTAGAAATTGCTCGGTGTGTCGTTCAGGTGCAGGCGAAACAAGCGCTCCAGCTGACGCCGGGTGACCTTGATCGATTCCGCCAATTCCAACGTACTCAGCGGCGGCTCGCTGTGCTGCTCCATCTCGCCAATCACGTGAACAAGCTTCTTGTTGCTGATGCCATAACGCGTCGCGACTTCCATGCGCTGGTGGTCTTTACGCGGACGGATGCGCCCGAGCACGAATTGCTCGCTGACCTGGATTGCCAGTTCCGGGCCATGGGACTGGGCGATCAGATCCAGCATTAAATCGATCGACGCGGTCCCGCCAGCGCTGGTGATGCGTCGACGGTCGATCTCGAATAACTCTTGGGTGACACTGAGCTGCGGATAGGACTCCTTGAAGGCGTCGATGGCCTCCCAGTGCAGGGTCAGGCGATGACCGTCGAGCAAACCTGCCTCAGCGAGGATGAAGCTGCCGGTGTCAATGGCGCCGAGCGTCACGCCTTCGTTGTCGAGGCGACGCAGCCAGTGCTCCAGCGCCGGAGTGGCGAATTTCAGCGGTTCGAAGCCGGCGACCACCCATAACGTCGCGCCTTTTTTCAACGGCTCCAGCGCCGCGTCGGCGTTGACCGACATGCCGTTACTGGCCAGCACCGCCCCACCATCGGCGCTCAATACATGCCAGCGATAGAGCTCGCCGCGAAAGCGATTGGCAACCCGCAATGGCTCGATTGCCGAGATAAATCCAATCGCCGAGAAACCCGGCATCAACAAGAAATAGAAATCCTGGGACATGGAGCGCACTCGTTCGACGGGTAGCGTGAAGACGTTGATACGCCACTTGCAGAAGGCATTCAAGAGCACAGGTCGCTGCAGTGCAAGAGTCGGTCGCCGCAGTGCGCTTTCGTGGCAGATTAGCTGCGTAACGTGACATCACCGGCGCACAGACGACCGGACCCACAATAATGAAACTGCCGAGGAACCTGAGAATGAAACGACTGATCAGCAGCTGTGTTCTTGCACTCAGTGGTACCGCTTTGCTGAGCGCCAGTGTCATGGCAGCCGAACCGGCGTCGTGCCAGAACGTGCGCATGGGCGTGGTGAACTGGACCGACGTGATCGCCACCAGTGCGATGACCCAGGTATTGCTCGACGGCCTCGGCTACAGCACCAAACAAACCAGCGCCTCCCAGCAAATCATCTTCGCCGGGATTCGCGATCAGCGCCTGGACCTGTTCCTGGGTTACTGGAACCCGCTGATGACCCAGACCATCACCCCGTTCGTCGACGCCAATCAGGTCAAGGTGCTTGAAGCGCCCAACTTGAAAGACGCACGTGCCACCCTCGCCGTTCCGACCTATCTCGCCGACAAGGGCCTGAAGACCTTCGCCGACATCGCCAAGTTCGAAAAAGAGCTGGGCGGCAAGATCTACGGCATCGAGCCAGGCTCAGGCGCCAACACCCAGATCAAGGCGATGATTGCCAAGAATCAGTTCGGCCTCGGCAAATTCCAACTGGTCGAATCCAGCGAGGCGGGCATGCTCGCGGCGGTGGATCGCGCCGTGCGCCGCAAGGAAGCCGTGGTGTTCTTCGGCTGGGCACCGCACCCCATGAACGTCAACGTACAGATGACCTATCTCACCGGCAGTGAAGACGCCCTCGGCCCTAACGAAGGCATGGCCACGGTTTGGACCGTGACCTCGCCGACCTACGCCGAGCAGTGCCCGAACATCGGTCGCCTGCTGAGCAACCTGACGTTCACCGCCGAAGATGAAAGCCGGATGATGCAGCCGCTGCTGGATCACAAGGACGCCTTCGAGTCCGCCAAACAGTGGCTGAAGGATCACCCGCAAGACAAGCAGCGCTGGCTGGAAGGCGTGACCACCTTCGACGGCAAGCCTGCGGCTGAAAACCTCAAGCTGACCAGCAAGTAACCCTCAATTGAACCACCGATTCGCGGCCCGAACGGGCTGCGAACGGGACCACCACGCCTGAAGGAAACCGCCAAATGAACCACGACGTCATCATCACCTGCGCACTCACCGGTGCTGGCGACACGACCGCCAAGAGCCCTCATGTGCCGGTCACCCCGAAACAGATTGCGGCCGCTGCCGTGGAGGCCGCCAAGGCCGGCGCTACCGTGGTTCACTGCCACGTTCGCGACCCCGAAACCGGCAAGTTCAGCCGTGACGTGGCGCTGTACCGCGAAGTGATGGAGCGCATCCGCGAAGCCGACGTGGACATCATCGTCAACCTCACTGCCGGCATGGGCGGCGACCTGGAAATCGGCGCGGGCGAGAACCCGATGGAGTTCGGCCCGAACACTGACCTGGTCGGCCCGTTGACTCGTCTGGCCCATGTCGAGGAACTGCTGCCGGAAATCTGCACCCTCGATTGCGGCACCCTGAACTTCGGCGATGGCGACACCATTTACGTCTCTACTCCGGCACAGCTGCGTGCGGGCGCCAAACGCATCCAGGAACTGGGCGTTAAGGCCGAGCTGGAGATCTTCGACACCGGTCACCTGTGGTTCGCCAAGCAGATGATCAAGGAAGGCCTGCTCGACAACCCGCTGTTCCAACTGTGCCTGGGCATCCCGTGGGGCGCGCCGGCTGACACCACTACCATGAAAGCCATGGTCGACAACCTGCCGGCCGACGCCGTGTGGGCCGGTTTCGGCATCGGCCGCATGCAAATGCCGATGGCCGCGCAAGCCGTGCTGCTGGGTGGCAACGTGCGAGTTGGGCTGGAAGACAACTTGTGGCTGGACAAGGGCGTACTGGCGACCAATGGCCAACTGGTCGAACGCGCCAGCGAAATCCTCAGCCGCCTCGGTGCCCGTGTGCTCACGCCTGCTGAGGGCCGCAAGAAAATGGGCCTGAAACAGCGCGGTTAATCCTCCCCACCCTTTTTCCCCTTGTGGGTGTGGGCTTTTGTGGCAAGGGTCTGCCCCACAAGGGAATCATCGAATTCTTCAGGAAATTGCCATGACCTTCATTACCGAAATCAAAACCTTCGCCGCACTGGGCAGCGGTGTCATCGGCAGCGGCTGGGTGTCCCGCGCCCTCGCCCACGGCCTCGACGTGGTGGCCTGGGACCCGGCCCCCGGTGCCGAAGCCGCCCTGCGCAAACGCGTCGCCAATGCCTGGGGCGCCCTTGAGAAACAAGGCCTGGCGCCCGGAGCCTCGCAGGATCGCCTGCGCTTTGTCGCAACCATCGAAGAATGCGTGCGCGACGCCGATTTCATCCAGGAAAGCGCTCCTGAGCGCCTGGAACTAAAACTGGAGTTGCACAGCAAGATCAGCGCCGCGGCCAAGCCCAATGCATTGATCGGCTCCAGCACCTCCGGCCTGTTGCCAAGCGAGTTCTACGAGAGTTCGACCCACCCGGAGCGCTGTGTGGTCGGCCACCCGTTCAACCCGGTTTACCTGTTGCCATTGGTGGAAGTGGTCGGTGGCAAGAATACCGCCCCCGAAGCCGTGCAGGCGGCTATGAAAGTCTACGAATCGCTTGGCATGCGCCCGCTGCACGTGCGCAAGGAAGTGCCGGGATTCATCGCCGACCGCTTGCTCGAAGCGCTGTGGCGCGAGGCGCTGCACCTGGTCAACGACGGTGTGGCGACGACCGGCGAAATCGACGACGCGATTCGTTTTGGCGCCGGTCTGCGTTGGTCGTTCATGGGCACATTCCTGACCTATACCCTGGCCGGTGGCGACGCCGGGATGCGCCACTTCATGGCACAGTTCGGCCCCGCCCTGCAGTTGCCATGGACCTACCTGCCGGCGCCGGAACTGACGGAAAAACTGATCGACGATGTGGTGGATGGCACCAGCGATCAGTTGGGCACACACAGCATTTCGGCGCTGGAGCGCTATCGTGATGATTGCCTGCTGGCGGTGCTGGAAGCCGTGAAGACCACCAAAGAGAAGCATGGGATGAGTTTCAGCGAGTAACCCGTACCACTGATCGTTCCCACGCTCTGCGTGGGAATGCAGCCCGGGACGCTCGGCGTCCCAAAAGATCGTGACGCAGAGCGTCACAGGAGGCGTTACCACGCAGAGCGTGGGAACGATCATCTCTGGAGAGCAAGATGCCCGCACTAACCACCTATCAAACCCGCATCATCCCCGATTGGGTCGACTACAACGGCCACCTGCGCGACGCGTTCTACCTGCTGATCTTCAGCTACGCCACCGATGCCCTGATGGACCGCCTCGGCATGGACAGCAGCAACCGCGAAGCCAGCGGCAACTCGCTGTTCACCCTGGAACTGCACCTCAACTACCTGCACGAAGTGAAGCTCGACGCCGAGGTCGAGGTGCACACGCAAATCATCGGCCACGACAGTAAACGCCTGCACCTCTACCACAGCCTGCACTTGGTGGGCGACGCCAAGGAGCTGGCGGGCAACGAGCAAATGCTGTTGCACGTCGACCTCGCCGGACCACGCTCCACGCCATTCAGCGAGCAGACCCTGGGCCGGCTGCAAGCCATGGTCGCCGAACAGAGCGACCTGCCCGCCCCCGCCTGCATCGGCCGAGTGATCGCATTGCCGCCAAAAAAATAACAAGGAGATCCCATGAACACTGCCGCCGCTTTTGCCGACTTCCGTACTTATCCGCTGATCAGCGCGCTGACAGGCGTGCAGGCCATGGCCGATCGTATCCTGGTGACGTGGGCCGACAACCGCGTCAGTCCCTTCCACCACCCATGGCTGCGGGACAATTGCCCGTGTCCGCAATGCGTCTACACGGTGACGCGCGAACAGGTGCTGGAAATCGTCGATGTGCCGGAGAACCTTAAGCCTGTCCAAACCAGTGTCGACCCTGATGGTTGCCTGAGCGTGCAGTGGCAGGATGGCCACCTCAGCCGCTTCGACCCTGGCTGGTTGCGGGCCCACGCCTACGACGACGAGTCCCGCGCCGAGCGCCTGGCAAGCAAGCCCAAGGCCAGGCTTTGGCACAGTGATTTGCAGTTGCCGGCGTTCGAGTATCAAGCACTGATGAACGACAACCAGGCGCTATTGCAATGGCTGCTGGCCGTGCGTGACACCGGCCTGACCCAGGTCCGTGGCGTACCCACCGAGCCTGGCTCGCTGAAGCTGGTCGCCCAGCGCATTTCCTTCATCCGCGAGAGCAATTTCGGCGTGCTGTTCAATGTGCAATCGAAGGCCGACGCCGACAGCAACGCCTACACCGCTTTCAACTTGCCGCTGCACAGCGACCTGCCGACGCGCGAGTTGCAACCGGGGCTGCAGTTCCTGCATTGCCTGGTCAACGATGCCGAGGGTGGCGAGAGTATTTTCGTCGACGGTTTTGCCATCGCCGAGGCGTTACGCCAGGAGGACCCCGAGTCGTTCCGAAGCCTGTGCGAAATCCCCGTGGAATTTCGCAATAAAGACCGCCTCAGTGACTATCGTTGCCTGGCGCCGATCATCGCGCTGGATACCTTGGGGCGGGTCTCGGAAATCCGCATGGCGAACTTTCTGCGAGGGCCGTTCGATGCATCGGTGGAGCAGATGCCCAGGCTCTATCACGCCTATCGCCGTTTCATCGCGATGACTCGCGAGCCTCGATTCAGGCTGATGCAAAGGCTCAACCCCGGCGAACTCTGGTGCTTCGACAATCGCCGTACCCTGCACGCGCGCAACGCCTTCGACCCTGCCACGGGTGCCCGCCATTTCCAGGGGTGTTATGTGGATCGGGATGAGTTGTTGTCGCGCATCCTCGTGCTACAGCGTTAAACCGCGTCATCGTTCTTCGCGAGCAAGCCCGCTCCCACAGGGATTTGCGCATGACGCAGATCAAATGTGGGAGATTCTATGGTTGAGGGGAAGCCCTCAACTGGTTTTCGGTTGGTATTCACTCTGCCCCTTCAGCAGGGCGAATACGATACGAGCGAGCTTGCGAGCCAGCATCACCAGGGCTTGAGTGGTGCTGAAACCCCGATTTCTTTGTTCTTGGTAAAACCCTTTCCAGGCTTCGGTTCGACTCGCCGACATAGCCGCATTGTGCAGAAGGCGGCGGGCTTCTGGATCGCCTCGCTTGGTCAAACTCCGGCGACCATCTTTTTGCCCTGATTTTGACACCCGCAAGTCCATTCCAAGAAAGGCGATAAAGGCATCTGCGTTTCGGAAGTCTCCGCGCTGGAACGCCGTGAGCAAGCGCGCGCCAGTCAAAAATCCAACCCCTTCAACTTTCAAGCAACGCTTCAACTGCCCCAGCAAACCGGCTTCTTTCAGCTGATCGTTGATCGTCTTTTCGATCAGCGTCTCAAGCTGCTGCATGGACTTTATTTGCTCGGAAAAAGCAGCCTTCAGCAAGGGCTCATTCGACCAGCTTTGCACTAGGCCGACCCTGGCCTGGACCAAGGCCGCCCGGCGGCGAAAAAGACTCAGGAGTTGGCGATACAGCGGTGTCGGCGGCGTCCATGGGTGAAGTTCTTCATGCTCGTTCTTCAGATAGCGAGCAAGCAGTTTGGCATCCAGTGCATCGGTTTTGGCACGGACCTTCACACCTTCTCGGTAATGTTTGAGCTCATAGCCGCCCACCATGTAAATCACGCAGCCGGCCTCAAAGGCCAGGTCAGCGAACTCCAGGTGGTAGATGTTGGTGGCTTCAATAGCAATAGCCACACTCCCCGGCAAGTCCTTTAACCACTTGTTGATGCTGGTTTTGTTGTTGGGAATCTCTTCAAGCAGGTCCAGTTCGGCGTGATAAATCACCAATTCTTTCTTGGCGACATCCACGCCCACGATCGGCTTTGAAACAGAAACCGGCATTGCCATAGGTTTTCCTCCGGGATAAGGTTTTAAGCACTTGAAGGGCTCACCCAGAGGCGCAGGCTTGTTCCTATCGTCGGTCTAGGCCAGATGCATTCTTTATCGGCGCTTGGGTGAAAGGAGGAGGGGCGAACTCTCCCACAGTCTGTACTGCGTCAACAGTCAGAATCGAGCCTTGTCCCTCCTCCTCCCTTCAAGTCCTACCATACAAGCGAGCCTGCTCGCGAAGGCGACTGTACAGACCACACAGAAACCACAGGCAAAAAAAAGCCCCGATCAAGCCGTGACAGGATCGAGGCAGAGGGTACTGTTGAGGAGCTGCCGCGGGAAGGTGACCAAACCCTCGTGAAGCAAGCTGGGTCCAGTGTGCCGACTCTCAGCGCAGGTAAATAGCCCGAAAACGACCTGTTCATAGTCAATGCTGCCATAACGACAAATCGCCCTTGCCGCCACTGCGTGCCACTACCAGAATCGACCCACGACATCATTCCCAGAAGAAGGATTTGCGTCATGATGCACGCCGATTTGATAGACCAGGAAGACCTGTTGGGCCAGCTCAAGTCATTGGGTTTTCAAGTGCCGAGCGGCGCGACGGCCGAACAGGCTTGCGAATGCGCGGTAAGGGGCCTGGACGATGCTCGGGCCTATGAACTTCGCAAGATGGTCAAGGAGATGTACACCAGCAGCGCGACGATCCTGCCGGCTGTGCGCCAGGCCATCGACAAGCAATTGCTGCCAGCGTTGGCGCAATACCAACAGAGCCACACCACCCGCTAAAACGCCTTCGCGAGCAGGCTCGCTCCCACATTCGACCGCATCCCAATGTTGGAACTCGGTCAATGTGGGAGCGAGCCTGCTCGCGAATGAAGCGACTCGCTATTAGAGCCTTACGCTGGCGAACGTCGACTCATTACGCGCCTGACTCAGCGCCGACAACGGCCCGGACAACGGTGAAAGCACCAATGCCTGTGGCAGCGGCATCATCGCCACTTGCTGCGTGGTGTTGGAACCTACGCGCTCGTCGCGTGGCGGAATGCCGAAGTACTCGCGGTAGCACTTGGAGAAGTGCGGCGTGGACACGAAGCCACAAACCGATGCCACTTCGATGATCGACATTGGCGTTTGCTTGAGCAGTTGCCGAGCGCGGATCAAGCGCAGCTTCAGGTAGTACCGCGAAGGCGAGCAATGCAGGTACTTCTGGAACAGCCGCTCCAGCTGACGACGGGACACGGCGACGTACACCGCCAGTTCGTCGAGGTCGATCGGCTCTTCGAGGTTGGCTTCCATCAGCGCGACGATTTCCTGCAGTTTCGGCTGGTTGGTGCCGAGCATGTGCTTGAGCGGTACGCGCTGGTGATCCTGTTCGTTGCGGATGCGCTCGTAGACGAACATCTCCGAGATCGCGGCCGACAGTTCACGACCGTGATCGCGGCTGATCAGGTGCAGCATCATGTCCAGCGGCGCGGTGCCGCCGGAGCTGGTGAAACGGTTACGGTCGAGGGTGAACAGGCGAGTACTCATGGCCACCCGCGGAAACGCTTCCTGCATCGCCGCCAGGCATTCCCAGTGCACGCTGCAATCGAAACCGTCGAGCAGGCCGGCGCACGCCAGGGCCCAGCTGCCGGTGCACACCGCACCCAGGCGACGGGACTGCCGCGCCTGGCTCTGCAGCCAAGACACGTGTTCGCGGGTAACCGTGCGTTGAATTCCGATACCGCCGCAGACAATCACGGTGTCCATTGGCGGGGCTTTGTGCATGGAGGCATCGGGGGTGATTTGCAGACCGTCACTGGCCCAGACTTGCCCGCCATCGACGGTGAGAGTGGTCCAACGATACAGCTCGCGACCGGACAGCTGGTTGGCCATACGCAGTGGTTCGACTGCGGATGCCAGGGAAATCAGCGTGAAATTGTCCAGCAACAGAAAGCCGATGGATTGTGGCGCACGGTTCTGGGGTTGGGCCCCGGAGTTGAACGTCGTCATCGCAGTATCTCCTCACACAAAGCGGGTGATGGCCTCAGGCGGAGGCTCTTGTTATTGCCATCGTTCTCGCATGGGAGACGGGCTTTGTAATGACAGAGCAAATGCCATGCCTAAATTTGAATACGCGTTCAATAACTCCTAAAAACGACGTCGGAATGTGTCTATATATGACGCGCAGGGAGTAAGGGTTATAAGTGCCATCAATGGCTGCAAGCGCTCTGCCCCGTTGCGTTTGAGCAAAACGGTAGCACTTGTGGGAACAGGGCTACAGGGAGCTCTGTAAGAGTGTCACCGCAGGCACGGGGTGACGGGTGGTCCGGGATGGGGAGGACCTGATTTTGAGGTCAGGTACTTATCTGTTAGCGACGCGCCAAAAGGAGGCGCATCAGGTATTACCTGTTCACTTAACGCGCAGTTTTGACTGGTCCGAATCACAAAGCCCCCCTCTGCCAAGCGTTATACTTCGCATCAGCGCATTATTTTGACGATCAAGAACGCCTCAACATCCTTATTACCTGCTCAGAGGCTGCCTCCAACCGCTCTTTAAATGCCTGAAGTTCCTTCACCTCAATCCCATCCCCATCCGCAGCGGGTAGATCAGCCATCGCTTTACGAAAAGAAAGATGAATGTCCAAGAATTGCAGGGTAGTCAAAGGCGTAGTCGAAGCACCATCTGCAAAAGACTCAACCAATGCAAGATCATCGCTCAAACGAGTATTGCCATTACCCAGACAGTCAGGCTCCGCGATGCGAAACCCGTTCATATGAGCGTTCCGAAACACATGGCCTGTACTTATCTCGACATTAGCGCTTCCCAACGCAGTGAATGCTCCAAATAGCTCATCGCGAACCTGCGTTTTTGAGGCCTTTGCGTCAAGCTCAGTGGGGATCAACTGTCGGACAGCTTTGATTTCCATACGCAACGATGACTTCGCTGTTTCACGATCCGGCAGCTTGCCAAGGATCAGCTCGATATCGTCTGCTGAAATAATCTCCCTTCCTGCAATGACCGTCCCTATATCGTTAAGGCTATTGAGTACATCAGCGACGATTGTGGCAGTTAACCCACCCCTGAGCTCAAGATGATAATGGGCCTGCATGCGACCATTTTCGGCAAAAGGAACGCCAAGAGTGTGGTAACGATCATAATCGTCGGGGTTACCCCGCCGGGGAATATTGCGGTCCTCGTAAACCAAACCATCACCGAGCAAGTGGTTTTCGTGAATCGTAATCAACGGTGATCCGGCGTCGCTCCTGGCCAAAACTTGGTTCAGCGCGGCTACCGTCGAGGTCACTGCGCGCTCAACCTCACGCTTGCACTCTTGACTGAGCGCCCCAGTGGCAAAATCCTTCGAAGCATTTAAATTCAACAGACCACGTTTGGCATGAACTTCGACACTATGCAACAACGTCGCTGGAGAGCAATCGTGCTTTACCCATGTCGACTTGCTGCTGCTAGCAAGATGAAGGGAGCCCGGATTGTTTGCTGTCGAAACCAATTGTTTGTGGACCAGCGTTGTTTTTGCGCGAAATCCCGGATCCAGAGGCACCACAGTGAGATTTGGAGCAGAACCGGATAGCGTTGTCGTCAGCATAAGTCCTCGATGCCAGGATATTGAGCCCGGCATTCTAGAATACGCTACTGCTGAAAAGGTTCTTCACGTGTATCCAAGTGATTCCTGAAGCTACATCAACACTCCACCGCACTCACCGCCAACCCACCCCGCGACGTCTCTTTATACTTGTCATGCATATCGGCCCCGGTATCGCGCATCGTGCGGATCACCCGGTCCAGGGAGATAAAGTGCTGGCCATCGCCGCGCAATGCCATCTGCGCCGCATTGATCGCCTTCACCGCGGCAATCGCGTTGCGCTCGATGCACGGCACCTGCACCAGGCCGCCCACCGGGTCACACGTGAGCCCCAGGTTGTGCTCCAGGCCGATTTCCGCCGCGTTGCACAGTTGTTCCGGTGTGGCGCCCAAAATTTCTGCCAAGCCCGCGGCCGCCATGGCGCAGGCCGAGCCGACTTCGCCCTGGCAGCCGACTTCGGCACCGGAGATGGAGGCGTTCTTCTTGCACAGGATCCCGACCGACGCCGCGCCGAGCATGTAGTCGACGACATTGGCGTCGGTCACGTCCTCGCTGAACTTCATGAAGTAGTGCAGCACCGCCGGGATGATCCCGGCCGCGCCATTGGTCGGTGCCGTGACCATGCGCCCACCAGCGGCGTTCTCTTCGTTGACCGCCAGGGCGAACAGGTTGACCCACTCCATGGCGCTCAGTGTCGAGCCGATCACGTTGGGCTTGTTCAGCTCCTGCAAGCTGCGATGCAATTTCGCCGCGCGACGGCGCACGTTCAGCCCGCCGGGCAGGATGCCCTCGTGCTTGAGGCCTTGTTCGACGCAATCCTGCATGGCGCGCCACAGGTGCATCAGGCCACTGCGGATTTCCTCTTCGCTGCGCCACACCTTCTCGTTGGCCATCATCAATTCGGCCACGCGCAGGTTGTGCTTTTTACACAACTCCAGCAGCTCGGCAGCGCTGGAAAAATCGTACGGCAGTTCGGTGTGATCCATGTCGACCACCCCGCTGCTGGCTTGTGCCTCATCGACGACAAAACCGCCACCCACCGAATAGTAGGTGTCGCGATGCAACTCGCCGTCATCGCCCTCGACAATCAGGGTCATGGCATTGGGATGGAATGGCAGGTTTTCGTCGATCAGGCGCATATCCCGAGCCCAGATGAACGGCACCGGCAGGCGGCCATCGAGTAACAGCGTGTCGGTTTCGCGCAGGGTGGCGATGCGGATGCCGATTTGCGACGGATCGATCGCGTCCGGCCACTCCCCCATCAAGCCCATGATCACCGCGTTGTCGCTGCCGTGGCCGATGCCGGTAGCCGACAGCGAACCAAAAAGCTGCACTTCGACGCGCCGAACCTGCTCAAGCTGCCCGCGTTCGCGCAAGCCCTGCACGAACAGCGCCGCGGCCCGCATAGGCCCCACGGTGTGTGAACTGGAAGGGCCAATGCCGATTTTGAACAGGTCGAAAACACTGATAGCCATTACTGCCGGACTCCTGGATGTGCCAACTCCAGGCGCAGAAGCGCCCGGTGACGGAGCTGCTACGCTCAAGCTGCAATCCGTCGTGATGGCCGCATCATCAGGCTTTTATCCTGTCGTTCGACGTCTCACACCGACGCACTCATGTCCACGAACGCCGCGTGTCTTTCACGTCGTGTTTTCGCCGTTTTTTTGCGGCTCAGACGGACAAAAGAGGCTGAAAAAATCTGTAAACGACGTCACCGACACTGGATGCGACCATCCCTGTACTGGTTACGACGCACCCTGTAGGCGTCAGATTTTCACTGGTACATGATCGTAACGACTCGATTGCAAGGCGCCGTGGTAGAGATGTCTCCAGAACGCCATCCAACCGCAACCTATAAGTGCGGTGGTTCCAGTCGGAAACTACTGCCAAAAAAAACACCAAGGAGTCCATCCATGAAAGGTTCCCCGTCGTTGTTGTTGGCCGCCCTGCTTAGTCTGCCGGTTATGGCGCAAGCCGCCGAACCGGCTCAATGCAGCACCGTAAACTTCTCCGATGTCGGCTGGACCGACATCACCGCAACGACCGCCACCACCAGCGTCGTGCTCAACGCCCTCGGCTACAAGACCAAGACCACCATGATTTCCGTGCCCGTGACCTACAAGTCCCTGGCCGACGGGAAGAACATGGACGTGTTCCTCGGTAACTGGATGCCGACCATGGAAAACGACATCAAGGCCTACCGCGACGCCGGCACCGTGGAAACCGTGCGCACCAACCTCAAGGGCGCCAAATACACCCTCGCCGTGCCACAAGCCCTGTACGACAAAGGGCTGCATGATTTTGCCGACATCGCCAAGTTCAAGAAGGAACTGGACGGCAAGATCTACGGCATCGAGCCCGGCAACGACGGCAACCGCCTGATCCAGAGCATGATCGACAAGAACGCCTTCGGCCTCAAGGACGCAGGCTTCAAGGTCGTCGAATCCAGCGAAGCGGGGATGCTCTCCCAGGTCGACCGCGCCCAGAAACGCGACACCGCCGTGGTCTTCCTCGGCTGGGCGCCGCACCCGATGAACAAGCGCTTCAAGATTCAATACCTGACCGGCGGCGACGATTTCTTTGGCCCGGATTTCGGTGCTGCCACCGTGGCGACCAACACCCGCAAGGGTTACGCCGAGGAGTGCAGCAACGTGGGCCAACTGCTGAAAAACCTGGAGTTCACTGTCGACATGGAGAGCGAACTGATGGGCAACATCCTGGACGACAAGATGAAGCCTGACGCGGCCGCCAAGGCCTGGCTGAAAAAGAATCCACAGGTGCTCGATACCTGGCTCGCTGGCGTGACCACCATTGACGGTAAACCAGGCCTGGAGGCCGTGAAAGCCAAACTCGCGCCTTGAATCGGGGAGCATCGCTTATGCCGGGCGGCTCACGCCGTCCGGGCTGTTAATTTCCTTGCATGCGGACGTTCACTACCATGCTGATTGATCAGAAAATCCCTTTAGGCCAGCACATCGCGAGCTTTGTCGAATGGTTGACGCAACACGGCGCCAACACCTTCGACGCCATTGCCGTGACGCTGGAAACGATGATCCACGGCGTGACTTTCGCGCTGACCTGGTTCAACCCGCTGGCACTGATCGGCCTCATCGCCCTCCTGGCCCACTTCATCCAGCGCAAATGGGGGCTGACCGCTTTCGTCATCGCCTCCTTTCTGCTGATCCTCAACCTGGGGTACTGGCAGGAAACCATGGAGACCCTGGCCCAGGTGCTGTTTGCCACCCTGGTCTGCGTGGTCATCGGCGTGCCACTGGGCATCGTCGCGGCGCACAAGCCAATGTTCTACACTTTTATGCGTCCGGTACTCGATCTGATGCAGACCGTACCGACCTTCGTTTACCTCATTCCTACCCTGACCCTCTTCGGGCTGGGTGTGGTGCCAGGCCTGATCTCCACGGTGGTATTCGCCATCGCCGCGCCGATCCGCCTGACCTACCTGGGCATCCGCGATGTCCCGCAAGAACTGATGGACGCCGGCAAGGCCTTTGGCTGCTCGCGTCGCCAGCTACTAACACGGATCGAACTGCCCCACGCCATGCCGAGCATCGCGGCCGGCATCACCCAGTGCATCATGCTGTCGCTGTCGATGGTGGTGATTGCGGCACTGGTGGGCGCCGACGGACTGGGTAAACCGGTGGTCAACGCACTGAACACTGCTGATATCGCCCTGGGCTTCGAAGCGGGCCTGGCGATCGTACTGCTGGCGATCATGCTCGACCGTATCTGCAAACAACCCGACGCGAAAGTAGGGGGTGACGCATGAGCATAATTCGCTTCGAAGACGTCGACGTGATCTTCACCAAGGATCCACGCGAAGCACTGAAACTTCTCGATCAAGGCTTGACCCGCAGCGAGATCCTGAAAAAGACCGGGCAAATCGTTGGCGTCGAAAAGGCCAGCCTGGATATCGAAAAAGGTGAAATCTGCGTGCTGATGGGCCTGTCCGGCTCCGGCAAGTCCAGCCTGCTGCGTTGCATCAACGGTCTCAACACCGTCAGCCGTGGCAAGCTGTTCGTCGAACACGAAGGCAAGCAGATCAACATCGCGTCCTGCTCCGCGGCCGAGCTGAAAATGATGCGCACCAAGCGCATTGCGATGGTGTTCCAGAAGTTCGCCCTGATGCCTTGGCTGACGGTGCGCGAGAACATCAGCTTCGGCCTGGAAATGCAGGGCCGTCCGGAGAAGGAACGCCGGAAACTGGTCGATGAAAAACTTGAGCTGGTGGGCCTGACCCAATGGCGCAACAAGAAACCCGATGAGCTGTCCGGTGGCATGCAGCAACGTGTGGGCCTGGCCCGTGCGCTGGCGATGGACGCCGACATTCTGCTGATGGACGAACCGTTCTCGGCACTCGACCCGCTGATCCGCCAGGGCCTGCAGGACGAACTGCTGGAGCTGCAACGCAAGCTGAGCAAGACCATCGTGTTCGTGAGCCACGACCTCGATGAAGCCCTGAAGCTCGGCAGCCGTATCGCGATCATGAAAGACGGCCGGATCATCCAGTACAGCAAGCCCGAAGAAATCGTCCTCAACCCTGCGGACGACTACGTGCGGACCTTCGTCGCCCACACCAACCCGCTGAACGTACTGTGCGGGCGCAGCCTGATGCGCACCCTGGACAACTGCAAGCGCATCAACGGCTCGGTGTGCCTCGATCCGGGCGGCGATTCGTGGCTTGACCTCGCCGAAGGCAACACCATCAAGGGCGCACGCCAGAACGGTGCGAGCCTGGACCTGCAGAACTGGATTCCAGGTCAGGCGGTCGAAGGCCTGGGCCGTCGGCCGACGCTGGTGGATTCCAACATCGGCATGCGCGACGCATTGCAGATTCGTTATCAGACCGGCAACAAACTGGTGTTGCACGACAACAACAAAGTGGTCGGGATTCTCGGCGACAGCGAGCTGTACCACGCGCTGCTCGGCAAGAACCTGGGCTAA

Protein sequences of DBSCAN-SWA_5

>NZ_CP051487|6348138:6390952|6373345_6374323_-|WP_008019494.1|DBSCAN-SWA
MSPAELHADSIVIDGLIIAKWNRELFEDMRKGGLTAANCTVSVWEGFQATVNNIAASQKLIRENSDLVIPVRTTADIRKAKEQGKTGILFGFQNAHAFEDQIGYVEVFKQLGVGIVQMCYNTQNLVGTGCYERDGGLSGFGREIVAEMNRVGVMCDLSHVGSKTSEEVILESKKPVCYSHCLPSGLKEHPRNKSDEELKFIADHGGFVGVTMFAPFLAKGIDSTIDDYAEAIEYTLNIVGEDSIGIGTDFTQGHGQDFFEYLTHDKGYARRLTSFGKIINPLGIRTVGEFPNLTETLLKRGHSERVVRKIMGENWVNVLKDVWGE
>NZ_CP051487|6348138:6390952|6375487_6376432_-|WP_020796077.1|DBSCAN-SWA
MSQDFYFLLMPGFSAIGFISAIEPLRVANRFRGELYRWHVLSADGGAVLASNGMSVNADAALEPLKKGATLWVVAGFEPLKFATPALEHWLRRLDNEGVTLGAIDTGSFILAEAGLLDGHRLTLHWEAIDAFKESYPQLSVTQELFEIDRRRITSAGGTASIDLMLDLIAQSHGPELAIQVSEQFVLGRIRPRKDHQRMEVATRYGISNKKLVHVIGEMEQHSEPPLSTLELAESIKVTRRQLERLFRLHLNDTPSNFYLRLRLEKARQLLRQTDMSVLEVSIACGFESPSYFTRSYRAKFERCPREDRRTAKA
>NZ_CP051487|6348138:6390952|6378624_6379590_+|WP_020796081.1|DBSCAN-SWA
MTFITEIKTFAALGSGVIGSGWVSRALAHGLDVVAWDPAPGAEAALRKRVANAWGALEKQGLAPGASQDRLRFVATIEECVRDADFIQESAPERLELKLELHSKISAAAKPNALIGSSTSGLLPSEFYESSTHPERCVVGHPFNPVYLLPLVEVVGGKNTAPEAVQAAMKVYESLGMRPLHVRKEVPGFIADRLLEALWREALHLVNDGVATTGEIDDAIRFGAGLRWSFMGTFLTYTLAGGDAGMRHFMAQFGPALQLPWTYLPAPELTEKLIDDVVDGTSDQLGTHSISALERYRDDCLLAVLEAVKTTKEKHGMSFSE
>NZ_CP051487|6348138:6390952|6389773_6390952_+|WP_020796090.1|holin|DBSCAN-SWA
MSIIRFEDVDVIFTKDPREALKLLDQGLTRSEILKKTGQIVGVEKASLDIEKGEICVLMGLSGSGKSSLLRCINGLNTVSRGKLFVEHEGKQINIASCSAAELKMMRTKRIAMVFQKFALMPWLTVRENISFGLEMQGRPEKERRKLVDEKLELVGLTQWRNKKPDELSGGMQQRVGLARALAMDADILLMDEPFSALDPLIRQGLQDELLELQRKLSKTIVFVSHDLDEALKLGSRIAIMKDGRIIQYSKPEEIVLNPADDYVRTFVAHTNPLNVLCGRSLMRTLDNCKRINGSVCLDPGGDSWLDLAEGNTIKGARQNGASLDLQNWIPGQAVEGLGRRPTLVDSNIGMRDALQIRYQTGNKLVLHDNNKVVGILGDSELYHALLGKNLG
>NZ_CP051487|6348138:6390952|6348138_6348645_-|WP_020796053.1|protease|DBSCAN-SWA
MKSLLALFSLIALPVMAAEPTLYGRYEYIALPEIGGEVLKAKMDTGALTASLSAKDIETFTRDGEDWVRFRLATKGASNKVYEHKVARISKIKTRSEEDEDDSEVIAPTKRPVVDLELCLGNVKRTVEVNLTDRSSFNYPLLIGAKALREFGAAVNPARRFTADKPDC
>NZ_CP051487|6348138:6390952|6353081_6353714_-|WP_020796059.1|DBSCAN-SWA
MTAANVYQQRPTNGAKAESSLHHADLASLVGKGRKNAGVTVREKKLLGHLTIRGDGHDAAFAAGVHKALGIELPGALTVIVKGETSLQWMGPDEWLLIVPTGEEFAAEQKLRKALGDLHIQIVNVSGGQQILELSGPNVRQVLMKSTSYDVHPNNFPVGKAVGTVFAKSQLVIRHTAEDTWELLIRRSFSDYWWLWLQDASAEYGLSVQA
>NZ_CP051487|6348138:6390952|6360041_6360770_-|WP_168759237.1|DBSCAN-SWA
MHTATHLKQRDRALDLLKWLALLSMVLDHLRYVGYSADWLYVPGRLAFPWFCLAIVINLTRKPAVATSGQWRYLSWLLMFSAVSEIPYRMFIPSPDTLNVMPTLALGLLVVLGWQDRTLQARLVAAGAVVLAALFARQLMFGFFGVMLPLAMLLVIRRPWYFALLPGVVCLAANQWQVLYYSVRQGNEVAMAAIATCLIAPWLGLFLLRHASDVKPPPMRRWAYALYPVHFLVLLALRQALA
>NZ_CP051487|6348138:6390952|6372736_6373267_-|WP_020796073.1|DBSCAN-SWA
MAKIAPQLPIEVDSETGVWTSDALPMLYVPRHFFVNNHMGIEEVLGAEAYAEILYKAGYKSAWHWCEKEAECHGLEGVAVFEHYMKRLSQRGWGLFKIQDIDLDKGTCSVKLEHSAFVYVYGKVGRKVDYMFTGWFAGAMDQILAARGSKIRTVAEQVYGGSEEGHEDGLFTVKPL
>NZ_CP051487|6348138:6390952|6376626_6377571_+|WP_020796078.1|holin|DBSCAN-SWA
MKRLISSCVLALSGTALLSASVMAAEPASCQNVRMGVVNWTDVIATSAMTQVLLDGLGYSTKQTSASQQIIFAGIRDQRLDLFLGYWNPLMTQTITPFVDANQVKVLEAPNLKDARATLAVPTYLADKGLKTFADIAKFEKELGGKIYGIEPGSGANTQIKAMIAKNQFGLGKFQLVESSEAGMLAAVDRAVRRKEAVVFFGWAPHPMNVNVQMTYLTGSEDALGPNEGMATVWTVTSPTYAEQCPNIGRLLSNLTFTAEDESRMMQPLLDHKDAFESAKQWLKDHPQDKQRWLEGVTTFDGKPAAENLKLTSK
>NZ_CP051487|6348138:6390952|6366573_6367344_-|WP_020796069.1|DBSCAN-SWA
MSTKIISLVSIGAHPTSGRPRRAEQDARAVELGLQLAGDNLQVLHAGDVGEPALRAYLGMGLEQLHVLEQPQGADALPALTAYLRDAGAQVVLTGSQAETGEGSGMLPFLLAEGLGWPLVVGLAQVESIDGGSALVLQALPRGQRRRLKVRLPFLATVDNAAPKPRQSAYGPARRGVLQANEVEIVDDELLAVATLQPAKPRPKRLKVIKAKSGADRMKAATAKASGGGGQVLKGVTAQAGAEAILKLLIEEGVVR
>NZ_CP051487|6348138:6390952|6350652_6351852_-|WP_020796056.1|DBSCAN-SWA
MSGNRGVVYLGAGKVEVQKIDYPKMQDPRGRKINHAVILRVVSTNICGSDQHMVRGRTTAQTGLVLGHEITGEVIEKGSDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVCLSVNPARPGGAYGYVDMGDWTGGQAEYAMVPYADFNLLKLPDRDRAMEKIRDLTCLSDILPTGYHGAVTAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNTVRLAHAKAQGFEIADLSLDTPLHEQIAALLGEPEVDCAIDAVGFEARGHGHDGVKHEAPATVLNSLMGVVRVAGKIGIPGLYVTEDPGAVDAAAKMGSLSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDRINIAEVVGVQVISLDQAPEGYGEFDAGVPKKFVIDPHKLFSAA
>NZ_CP051487|6348138:6390952|6384889_6385996_-|WP_168759061.1|DBSCAN-SWA
MLTTTLSGSAPNLTVVPLDPGFRAKTTLVHKQLVSTANNPGSLHLASSSKSTWVKHDCSPATLLHSVEVHAKRGLLNLNASKDFATGALSQECKREVERAVTSTVAALNQVLARSDAGSPLITIHENHLLGDGLVYEDRNIPRRGNPDDYDRYHTLGVPFAENGRMQAHYHLELRGGLTATIVADVLNSLNDIGTVIAGREIISADDIELILGKLPDRETAKSSLRMEIKAVRQLIPTELDAKASKTQVRDELFGAFTALGSANVEISTGHVFRNAHMNGFRIAEPDCLGNGNTRLSDDLALVESFADGASTTPLTTLQFLDIHLSFRKAMADLPAADGDGIEVKELQAFKERLEAASEQVIRMLRRS
>NZ_CP051487|6348138:6390952|6380216_6381380_+|WP_168759060.1|DBSCAN-SWA
MNTAAAFADFRTYPLISALTGVQAMADRILVTWADNRVSPFHHPWLRDNCPCPQCVYTVTREQVLEIVDVPENLKPVQTSVDPDGCLSVQWQDGHLSRFDPGWLRAHAYDDESRAERLASKPKARLWHSDLQLPAFEYQALMNDNQALLQWLLAVRDTGLTQVRGVPTEPGSLKLVAQRISFIRESNFGVLFNVQSKADADSNAYTAFNLPLHSDLPTRELQPGLQFLHCLVNDAEGGESIFVDGFAIAEALRQEDPESFRSLCEIPVEFRNKDRLSDYRCLAPIIALDTLGRVSEIRMANFLRGPFDASVEQMPRLYHAYRRFIAMTREPRFRLMQRLNPGELWCFDNRRTLHARNAFDPATGARHFQGCYVDRDELLSRILVLQR
>NZ_CP051487|6348138:6390952|6358494_6359748_-|WP_020796061.1|DBSCAN-SWA
MFSKQDQIQGYDDALLAAMNAEEQRQEDHIELIASENYTSKRVMEAQGSGLTNKYAEGYPGKRYYGGCEHVDKVEALAIERAKQLFGADYANVQPHSGSSANSAVYLALLQAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGIDTKTGLIDYDEVERLAVECKPKMIVAGFSAYSKTLDFPRFRQIADKVGALLFVDMAHVAGLVAAGLYPNPLPYADVVTTTTHKTLRGPRGGLILAKSNEEIEKKLNAAVFPGAQGGPLMHVIAGKAVCFKEALEPGFKAYQQQVIDNAQAMAGVFIKRGYDVVSGGTDNHLFLVSLIRQGLTGKEADAALGRAHITVNKNAVPNDPQSPFVTSGLRIGTPAVTTRGFKVTQCVTLAGWICDILDNLGDADVEANVAQQVSALCADFPVYR
>NZ_CP051487|6348138:6390952|6374558_6374960_+|WP_033044083.1|DBSCAN-SWA
MKFIVLALALIATGVHAAEESEDTPCDKVENDVQTLECSAFSKTTAEDLLSENYKSLNERMQSLYGKNPSQLAEITAKIKAAQQQWLKTRDADCAIEAFPATAGSKAFTIAQNDCVARMSDERSEFLETIGQE
>NZ_CP051487|6348138:6390952|6375019_6375436_+|WP_020796076.1|DBSCAN-SWA
MKVCGIEIKGSEAIIAVAALDGSTLSHVALATKKIALEDDDEAANVKVFAAQVASFVRENSIDRIVIKKRSKKGEFAGGPTTFKIEGVFQLLENCEVTLLSPQTINAQAKKHGFEPPETLNKYQHEAYKAACSALLKK
>NZ_CP051487|6348138:6390952|6356876_6357206_-|WP_008057118.1|DBSCAN-SWA
MLHIFCPHCGELRSEEEFHASGQAHIPRPLDPNSCTDEEWGDYMFFRDNPRGLHHELWDHVAGCRQYFNVTRDTVTYEILETYKIGTKPQFTDKTDSPKAATTALGEKV
>NZ_CP051487|6348138:6390952|6363837_6365133_+|WP_020796067.1|DBSCAN-SWA
MDVTTTLSLGDPLEPARKATAQMLQERERTFSLPQPFYSDERLFDIDMQEIFQKEWLIAGMTCEIPAKGNYLTLQVGKNPIIVIRGAEGVVHAFHNVCRHRGSRLCTSEKGKVAKLVCHYHQWTYELDGRLLFAGTEMGADFDMKQYGLKPVNVKTAGGYIFISLSENPPAIDDFLSTLSHYMEPYDMENTKVAITTTLMEKANWKLVLENNRECYHCNASHPELLKTLLEWDDVTDPRADQAFKDHVAASAAAWEAEKIPYAHASFGLRNRIVRMPLLKGTVSMTLDGKQGCAKLMGRIKNPDLGSMRILHLPHSWNHCMGDHIIVFTVWPISAQETMVTTKWIVHKDAVEGVDYDVDRMRQVWDATNDQDRRLAEENQRGINSTAYQPGPYSKTYEFGVVNFVDWYSERLLSNLGAEPAPYLKGVPVQG
>NZ_CP051487|6348138:6390952|6388931_6389777_+|WP_020796089.1|holin|DBSCAN-SWA
MLIDQKIPLGQHIASFVEWLTQHGANTFDAIAVTLETMIHGVTFALTWFNPLALIGLIALLAHFIQRKWGLTAFVIASFLLILNLGYWQETMETLAQVLFATLVCVVIGVPLGIVAAHKPMFYTFMRPVLDLMQTVPTFVYLIPTLTLFGLGVVPGLISTVVFAIAAPIRLTYLGIRDVPQELMDAGKAFGCSRRQLLTRIELPHAMPSIAAGITQCIMLSLSMVVIAALVGADGLGKPVVNALNTADIALGFEAGLAIVLLAIMLDRICKQPDAKVGGDA
>NZ_CP051487|6348138:6390952|6370660_6372721_-|WP_033044081.1|DBSCAN-SWA
MAFEAMFQPIQIGKLTIRNRVLSTAHAEVYATDGGMTTDRYVKYYEEKAKGGIGLAICGGSSVVAIDSPQEWWSSVNLSTDRIIPHFQNLADAMHKHGAKIMIQITHMGRRSRWDGFNWPTLMSPSGVREPVHRATCKTIEPEEIWRVIGNYAQAARRAKAGGLDGVELSAVHQHMIDQFWSPRVNKRTDEWGGTFEGRMKFGLEVLKAVRAEVGDDFCVGMRICGDEFHPDGLSHEDMKQIAKYYDDTGMLDFIGVVGSGCDTHNTLANVIPNMSYPPEPFLHLAAGIKEVVKVPVLHAQNIKDPNQATRILEGGYVDMVGMTRAHIADPHLIAKIKMGQIDQIKQCVGANYCIDRQYQGLDVLCIQNAATSREYMGLPHIIEKTTGVKRKVVVVGAGPAGMEAARVAAERGHDVTLFEKKDFIGGQITTASKAPQRDQIAGITRWYQLELARLKVDLRLGTAADAPTIMDLRPDVVVLAVGGHPFIEQNEHWGAAEGLVVSSWDILDGKVAPAKNVLVYDTICEFTGMSTADFLADKGSQVEIVTDDIKPGVAIGGTSFPTYYRSMYPKEVIMTGDMMLEKVYREGDKLIAVLENEYTGAKEERVVDQVVIENGVRPDEEIYYAMKEGSRNKGQIDVEALFAIKPQPCLEQKGDGYLLFRIGDCVAQRNVHAAIYDALRLCKDF
>NZ_CP051487|6348138:6390952|6387906_6388854_+|WP_020796088.1|holin|DBSCAN-SWA
MKGSPSLLLAALLSLPVMAQAAEPAQCSTVNFSDVGWTDITATTATTSVVLNALGYKTKTTMISVPVTYKSLADGKNMDVFLGNWMPTMENDIKAYRDAGTVETVRTNLKGAKYTLAVPQALYDKGLHDFADIAKFKKELDGKIYGIEPGNDGNRLIQSMIDKNAFGLKDAGFKVVESSEAGMLSQVDRAQKRDTAVVFLGWAPHPMNKRFKIQYLTGGDDFFGPDFGAATVATNTRKGYAEECSNVGQLLKNLEFTVDMESELMGNILDDKMKPDAAAKAWLKKNPQVLDTWLAGVTTIDGKPGLEAVKAKLAP
>NZ_CP051487|6348138:6390952|6352053_6352911_-|WP_020796057.1|DBSCAN-SWA
MSRAPDTWILTADCPSVLGTVDAVTRFLFEQGCYVTEHHSFDDRLSGRFFIRVEFRQPEGFDEQSFRAGLAERGASFGMVFELTPPHYRPKVVIMVSKADHCLNDLLYRQRIGQLSMDVVAVVSNHPDLKPLADWHQIPYYHFPLDPNDKPSQERQVLQVIEESGAELVILARYMQVLSPELCRKLDGRAINIHHSLLPGFKGAKPYHQAYNKGVKLVGATAHYINNDLDEGPIIAQGVEVVDHSHYPEDLIAKGRDIEGLTLARAVGYHIERRVFLNANRTVVL
>NZ_CP051487|6348138:6390952|6383297_6384401_-|WP_007975492.1|DBSCAN-SWA
MTTFNSGAQPQNRAPQSIGFLLLDNFTLISLASAVEPLRMANQLSGRELYRWTTLTVDGGQVWASDGLQITPDASMHKAPPMDTVIVCGGIGIQRTVTREHVSWLQSQARQSRRLGAVCTGSWALACAGLLDGFDCSVHWECLAAMQEAFPRVAMSTRLFTLDRNRFTSSGGTAPLDMMLHLISRDHGRELSAAISEMFVYERIRNEQDHQRVPLKHMLGTNQPKLQEIVALMEANLEEPIDLDELAVYVAVSRRQLERLFQKYLHCSPSRYYLKLRLIRARQLLKQTPMSIIEVASVCGFVSTPHFSKCYREYFGIPPRDERVGSNTTQQVAMMPLPQALVLSPLSGPLSALSQARNESTFASVRL
>NZ_CP051487|6348138:6390952|6377645_6378533_+|WP_020796079.1|DBSCAN-SWA
MNHDVIITCALTGAGDTTAKSPHVPVTPKQIAAAAVEAAKAGATVVHCHVRDPETGKFSRDVALYREVMERIREADVDIIVNLTAGMGGDLEIGAGENPMEFGPNTDLVGPLTRLAHVEELLPEICTLDCGTLNFGDGDTIYVSTPAQLRAGAKRIQELGVKAELEIFDTGHLWFAKQMIKEGLLDNPLFQLCLGIPWGAPADTTTMKAMVDNLPADAVWAGFGIGRMQMPMAAQAVLLGGNVRVGLEDNLWLDKGVLATNGQLVERASEILSRLGARVLTPAEGRKKMGLKQRG
>NZ_CP051487|6348138:6390952|6362442_6363543_-|WP_020796065.1|DBSCAN-SWA
MSNSFLNPVTTQTWANGRHIVRCVKVIQETWDVRTFCFMADQPIMFFFKPGQFVTLELEIEGQQIMRSYTISSSPSVPYSFSVTIKRVPGGKVSNWLHDTLHEGQELAVHGPVGLFNAMDFTAPKVLYLSGGVGITPVMSMARWFYDTNGNVDMVFIHSARSPKDIIYHRELEHMASRIDNFSLHLICEKHGMGEPWAGYRGYLNHRMLELMAPDFLEREVFCCGPTPYMNAVKRLLEAAGFDMKRYHEESFGATPPEARADAVEHAEQAAEAPEVDVADLHQVEFISSGKSIRVAPGETVHAAAAKVGLLIPKACGMGICGTCKVLKLGGEVEMEHNGGITEEDEAEGYILSCCSVPKGDVRIEF
>NZ_CP051487|6348138:6390952|6382928_6383195_+|WP_020796085.1|DBSCAN-SWA
MMHADLIDQEDLLGQLKSLGFQVPSGATAEQACECAVRGLDDARAYELRKMVKEMYTSSATILPAVRQAIDKQLLPALAQYQQSHTTR
>NZ_CP051487|6348138:6390952|6379727_6380204_+|WP_168759059.1|DBSCAN-SWA
MPALTTYQTRIIPDWVDYNGHLRDAFYLLIFSYATDALMDRLGMDSSNREASGNSLFTLELHLNYLHEVKLDAEVEVHTQIIGHDSKRLHLYHSLHLVGDAKELAGNEQMLLHVDLAGPRSTPFSEQTLGRLQAMVAEQSDLPAPACIGRVIALPPKK
>NZ_CP051487|6348138:6390952|6368579_6370526_-|WP_168759058.1|DBSCAN-SWA
MLNTLLPILIFAALGLAALGALRRVNMWRRGRASKVDLIGGLFAMPKRYMVDLHHVVARDKYIANTHVATAGGAVASIVLAILVHGFGLHNRFLGYALLLMSAVMFVGAVFVYLRRRNPPARLSKGPWMRLPKSLMAFSVSFFLVTLPVAGILPENFGGWLLAVILGIGVLWGVSELFFGMTWGGPMKHAFAGALHLAWHRRAERFGGGRSTGLKPLDLNDPSAPLGVEKPKDFTWNQLLGFDACVQCGKCEAACPAFAAGQPLNPKKLIQDMVVGLAGGTDAKFAGSPYPGKPIGEHAGNPHQPIVNGLVDAETLWSCTTCRACVEECPMMIEHVDAIVDMRRHLTLEKGATPNKGAEVLENLIATDNPGGFAPGGRMNWAADLNLNLLSEKKSTDVLFWVGDGAFDMRNQRTLRAFVKVLKAAKIDFAVLGLEERDSGDVARRLGDEATFQLLAKRNIQTLAKYSFNRIVTCDPHSFHVLKNEYGAFDGNYLVQHHSTYMAEIIDAGALNLGQHKGDSVTYHDPCYLGRYNGEYEAPRQVLRALGIEVKEMQRSGFRSRCCGGGGGAPITDIPGKQRIPDMRMEDIRETGAELVAVGCPQCTAMLEGVVEPRPLIKDIAELVADALLEDQAPKSATPAKREPAEVH
>NZ_CP051487|6348138:6390952|6362179_6362362_+|WP_168759056.1|DBSCAN-SWA
MEAERTTLKSEPIDRQRYLELAQPGNFYKYQGMTFEVKEKTFLSLGGDQYEIEVKTTPVK
>NZ_CP051487|6348138:6390952|6367359_6368580_-|WP_168759057.1|DBSCAN-SWA
MSDIIRRDPRAEWIARNRLHPLHAAMQPAQHSWMGPNGVIRKNPHGIGFIGPNGIKRIDRSGAQQGGTTKRSAAVEVQLPLHQVSAPAFFICVVPDMVGGRLSSHDRDLLGLAHQLAGSDGAVLAVVFGEHKENAFSTAGVDRLLVLEGEEFSGYAPEQRVQGLRAVDNQFNPRHWLLPDSRSGGGELGRRFAAALGERPATRVWQVKDQECIGRAGAGLQDLARPVARLILAAVECAEPVSETRHEVLPVELSTAVARSLSRIEDLGAVAVDPAAIPMAEAEFIFSGGNGVKDWDLFHQAAAALGATEGASRVAVDDGFMARDRQVGASGTWVTARVYVAVGISGAIQHLQGIGACDKVVAINLDPGCDMIKRADLSVIGESAEILRALIAAVEAYRNDAKRDAA
>NZ_CP051487|6348138:6390952|6348919_6349807_+|WP_020796054.1|DBSCAN-SWA
MRRLLTGCFVTLLLLLNTLVLIGPLMVFALLKLVLPGRFRDYASWVVMWIAETWSEIDKLIFRLCIPTRWDIRGGDDLRRDTSYLVISNHQSWVDIPALIQTLNRRTPFFKFFLKKELIWVPFLGLAWWALDYPFMKRYTKAFLAKNPELAGKDLEITKQACELFKRQPVTVVNYLEGTRYTSAKSTQQQSPFTHLLRPKAGGVAFVLAAMGEQLDAILDVTVVYPQQAIPGFWDLISGNVPRVIIDIKTRELDPALWQGDYENDPLFREKVQNWVNQLWNEKDRRIDDLRAESR
>NZ_CP051487|6348138:6390952|6357220_6358471_-|WP_007980419.1|DBSCAN-SWA
MQRYSGFGLFKHSLSHHENWQRMWRTPTPKKVYDVVIVGGGGHGLATAYYLAKEHGITNVAVVEKGWLGGGNTARNTTIVRSNYLWDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVYNLCHTLQDIRDSERRVSANRLNGVDGELLDAKQVADEIPYLDCSKNTRYPVMGATVQRRGGVARHDAVAWGFARAADALGVDLIQQTEVIGFRKENGVCIGVETNKGFIGAKRVGVVTAGNSGHMAKLAGFRLPIESHPLQALVSEPIKPIIDSVIMSNAVHGYISQSDKGDLVIGAGIDGYNGYGQRGSYPVIEHTIQAIVEMFPVLSRVRMNRQWGGIVDTTPDACPIISKTPVPNMFFNCGWGTGGFKATPGSGNVFAASLAKGEMHPLAAPFSIDRFHNGALIDEHGAAAVAH
>NZ_CP051487|6348138:6390952|6352907_6353069_-|WP_020796058.1|DBSCAN-SWA
MEAINCGSEPARDELEGNALIQEIRVIVNVHREQARSHKMQLSFIDASGVTAL
>NZ_CP051487|6348138:6390952|6353862_6356880_-|WP_168759054.1|DBSCAN-SWA
MSQINRLSNGGRIDRNKVLTFTFNGQSYKGFEGDSLAAALLANGVDIIGRSFKYSRPRGIFAAGAEEPNAVLQIGATEATQIPNVRATQQALYQGLVATSTNGWPSVNNDMMGILGKVGGKLMPPGFYYKTFMYPQSFWMTYEKYIRKAAGLGRSPTENDPDTYDYMNQHCDVLIVGAGPAGLAAALAAARSGARVILADEQEEFGGSLLDSRESLDGKPATEWVASVIAELKNTPDVLLLPRATVNGYHDHNFLTIHERLTDHLGDRAPIGQVRQRIHRVRAKRVVLATGAHERPLVYGNNDVPGNMLAGAVSTYVRRYGVAPGKKLVLSTNNDHAYRVALDWLDAGLQVVAVADARSNPRGALVEEARAKGIRILTGSAVIEARGTKHVTAARVAAIDVKGHKVTSPGEWLDCDIVASSGGYSPVVHLASHLGGKPIWREDILGFVPGEAPQKRVCVGGINGVYGLGDSLADGFEGGVRAASEAGFGAVEATLPKALTRLEEPTLALFQVPHEKNTARAPKQFVDLQNDVTAAAIELATREGFESVEHVKRYTALGFGTDQGKLGNVNGLAIAARSLNVTIPQMGTTMFRPNYTPVTFGAVAGRHCGHIFEPVRYTALHQWHLKNGAEFEDVGQWKRPWYFPKSGEDMHAAVKRECKAVRDSVGLLDASTLGKIDIQGPDSREFLNRIYTNAWTKLDVGKARYGLMCKEDGMVFDDGVTACLADNHFVMTTTTGGAARVLQWLEIYHQTEWPDLKVYFTSVTDHWATMTLSGPNSRKLLSEVTDADLSNEAFPFMTWKEAQVGGVPARIFRISFTGELSYEVNVQADYAMGVLEKIVDAGKKYNLTPYGTETMHVLRAEKGFIIVGQDTDSSMTPDDLNMGWCVGRNKPFSWIGWRGMNREDCVRDQRKQLVGLKPIDPNKWLPEGAQLVFNTKQAIPMTMVGHVTSSYLHNSLGYSFAMGVVKGGLNRMGERVFAPLADGSVIEAEIVSSVFFDPKGERQNV
>NZ_CP051487|6348138:6390952|6365984_6366551_-|WP_020796068.1|DBSCAN-SWA
MAVEFRPAVRADAREIARLFQISSEGAADYIWSQIAEPGQDLLDVGALRYARDDVDFSWQNCLIAEAEGKVIGMLHSYVMRHDPFAAPVTDPVLAPYAKMEIPDTLYISSLALHEGWRNQGLGKQFLAYAYDRANRLGLNGLSLIDYAANTGARRFYERHGFRVVDTCQIAPHPMIRVTGEAYLMYRP
>NZ_CP051487|6348138:6390952|6386091_6387468_-|WP_151143613.1|DBSCAN-SWA
MAISVFDLFKIGIGPSSSHTVGPMRAAALFVQGLRERGQLEQVRRVEVQLFGSLSATGIGHGSDNAVIMGLMGEWPDAIDPSQIGIRIATLRETDTLLLDGRLPVPFIWARDMRLIDENLPFHPNAMTLIVEGDDGELHRDTYYSVGGGFVVDEAQASSGVVDMDHTELPYDFSSAAELLELCKKHNLRVAELMMANEKVWRSEEEIRSGLMHLWRAMQDCVEQGLKHEGILPGGLNVRRRAAKLHRSLQELNKPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIIPAVLHYFMKFSEDVTDANVVDYMLGAASVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGATPEQLCNAAEIGLEHNLGLTCDPVGGLVQVPCIERNAIAAVKAINAAQMALRGDGQHFISLDRVIRTMRDTGADMHDKYKETSRGGLAVSAVEC
>NZ_CP051487|6348138:6390952|6360901_6361942_+|WP_168759055.1|DBSCAN-SWA
MTDKSQQFASDNYSGICPEAWAAMEQANHGHQRAYGDDEWTARASDDFRKLFETDCEVFFAFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLIARTENGKLTPESIREVALKRQDIHYPKPRVVTLTQATEVGSVYTPDEIRAISATCKELGLNLHMDGARFSNACAFLGCTPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASKMRFLSAPWVGILENDAWLKYARHANSCAQLLAELVSDIPGVELMFPVQANGVFLQLSEPAIAALTAKGWRFYTFIGNGGARFMCSWDTEEERVRELAADIREVMSH
>NZ_CP051487|6348138:6390952|6349808_6350390_-|WP_168759053.1|DBSCAN-SWA
MKISRGFVLASLMTLVVSPAFAQFSLSDAASAISGMKGNAATEAAPTSETADLLGALTQLNITPEQAVGGAGAMLGLAKNQLSSTDYSELAKSVPGIDILSGGGELGALAGLLGSSGKAAGLDNALGNVKDTNDLNNAFSALGMDTGMIGMFTPVILQYLGQQGVGGSLLSSLGSIWGTGTGTDTGFGTSTGS
>NZ_CP051487|6348138:6390952|6381476_6382424_-|WP_168757207.1|transposase|DBSCAN-SWA
MAMPVSVSKPIVGVDVAKKELVIYHAELDLLEEIPNNKTSINKWLKDLPGSVAIAIEATNIYHLEFADLAFEAGCVIYMVGGYELKHYREGVKVRAKTDALDAKLLARYLKNEHEELHPWTPPTPLYRQLLSLFRRRAALVQARVGLVQSWSNEPLLKAAFSEQIKSMQQLETLIEKTINDQLKEAGLLGQLKRCLKVEGVGFLTGARLLTAFQRGDFRNADAFIAFLGMDLRVSKSGQKDGRRSLTKRGDPEARRLLHNAAMSASRTEAWKGFYQEQRNRGFSTTQALVMLARKLARIVFALLKGQSEYQPKTS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020796053.1|6348138_6348645_-|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_020796054.1|6348919_6349807_+	acyltransferase	NA	NA	NA	NA
WP_168759053.1|6349808_6350390_-	DUF2780 domain-containing protein	NA	NA	NA	NA
WP_020796056.1|6350652_6351852_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	2.3e-09	26.6
WP_020796057.1|6352053_6352911_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_020796058.1|6352907_6353069_-	hypothetical protein	NA	NA	NA	NA
WP_020796059.1|6353081_6353714_-	sarcosine oxidase subunit gamma family protein	NA	NA	NA	NA
WP_168759054.1|6353862_6356880_-	sarcosine oxidase subunit alpha	NA	NA	NA	NA
WP_008057118.1|6356876_6357206_-	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_007980419.1|6357220_6358471_-	sarcosine oxidase subunit beta	NA	NA	NA	NA
WP_020796061.1|6358494_6359748_-	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	1.0e-100	53.2
WP_168759237.1|6360041_6360770_-	conjugal transfer protein TraX	NA	NA	NA	NA
WP_168759055.1|6360901_6361942_+	low specificity L-threonine aldolase	NA	NA	NA	NA
WP_168759056.1|6362179_6362362_+	hypothetical protein	NA	NA	NA	NA
WP_020796065.1|6362442_6363543_-	glycine-betaine demethylase subunit GbcB	NA	NA	NA	NA
WP_020796067.1|6363837_6365133_+	glycine-betaine demethylase subunit GbcA	NA	NA	NA	NA
WP_020796068.1|6365984_6366551_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_020796069.1|6366573_6367344_-	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_168759057.1|6367359_6368580_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_168759058.1|6368579_6370526_-	dimethylglycine demethylation protein DgcB	NA	NA	NA	NA
WP_033044081.1|6370660_6372721_-	dimethylglycine demethylation protein DgcA	NA	NA	NA	NA
WP_020796073.1|6372736_6373267_-	hypothetical protein	NA	NA	NA	NA
WP_008019494.1|6373345_6374323_-	membrane dipeptidase	NA	NA	NA	NA
WP_033044083.1|6374558_6374960_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_020796076.1|6375019_6375436_+	DUF3010 family protein	NA	NA	NA	NA
WP_020796077.1|6375487_6376432_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_020796078.1|6376626_6377571_+|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020796079.1|6377645_6378533_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_020796081.1|6378624_6379590_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_168759059.1|6379727_6380204_+	thioesterase	NA	NA	NA	NA
WP_168759060.1|6380216_6381380_+	gamma-butyrobetaine dioxygenase	NA	NA	NA	NA
WP_168757207.1|6381476_6382424_-|transposase	IS110 family transposase	NA	NA	NA	NA
WP_020796085.1|6382928_6383195_+	hypothetical protein	NA	NA	NA	NA
WP_007975492.1|6383297_6384401_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_168759061.1|6384889_6385996_-	hypothetical protein	NA	NA	NA	NA
WP_151143613.1|6386091_6387468_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_020796088.1|6387906_6388854_+|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_020796089.1|6388931_6389777_+|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_020796090.1|6389773_6390952_+|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.7e-26	37.6