CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP040612	Campylobacter sp. CFSAN093241 chromosome, complete genome	2 crisprs	DEDDh,WYL,cas14j,cas2,cas1,cas9,csa3	0	8	1	0

1. NZ_CP040612

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP040612_1

• CRISPR_ID: NZ_CP040612_1
• CRISPR_location: 1464039-1464272
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NZ_CP040612_1

Consensus_repeat	Method
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRT
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	PILER-CR
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	CRISPRCasFinder

spacers of NZ_CP040612_1

>1.1|1464075|30|NZ_CP040612|CRT
TAATGGTGTTGTTAATTGGAATGCAAAAGG
>1.2|1464141|30|NZ_CP040612|CRT
ACTTTAGTTTTAGACTTTGGAACAGTCGAG
>1.3|1464207|30|NZ_CP040612|CRT
TATTTGAACGCTTAAAATCAAGAAAATATT
>1.4|1464076|30|NZ_CP040612|PILER-CR
TAATGGTGTTGTTAATTGGAATGCAAAAGG
>1.5|1464142|30|NZ_CP040612|PILER-CR
ACTTTAGTTTTAGACTTTGGAACAGTCGAG
>1.6|1464208|30|NZ_CP040612|PILER-CR
TATTTGAACGCTTAAAATCAAGAAAATATT
>1.7|1464075|31|NZ_CP040612|CRISPRCasFinder
TAATGGTGTTGTTAATTGGAATGCAAAAGGG
>1.8|1464141|31|NZ_CP040612|CRISPRCasFinder
ACTTTAGTTTTAGACTTTGGAACAGTCGAGG
>1.9|1464207|31|NZ_CP040612|CRISPRCasFinder
TATTTGAACGCTTAAAATCAAGAAAATATTG

CRISPR arrays and Neighbor proteins around NZ_CP040612_1

CRISPR arrays

The CRISPR arrays of NZ_CP040612_1

>merge|NZ_CP040612|1|1464039-1464272|CRT,PILER-CR,CRISPRCasFinder
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATTAATGGTGTTGTTAATTGGAATGCAAAAGGGTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATACTTTAGTTTTAGACTTTGGAACAGTCGAGGTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATTATTTGAACGCTTAAAATCAAGAAAATATTGTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP040612|1|1|1464039-1464272|CRT
ATTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TAATGGTGTTGTTAATTGGAATGCAAAAGG
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ACTTTAGTTTTAGACTTTGGAACAGTCGAG
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TATTTGAACGCTTAAAATCAAGAAAATATT
GTTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP040612|1|1|1464040-1464272|PILER-CR
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATT	AATGGTGTTGTTAATTGGAATGCAAAAGGG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATA	CTTTAGTTTTAGACTTTGGAACAGTCGAGG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAATT	ATTTGAACGCTTAAAATCAAGAAAATATTG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

>NZ_CP040612|1|1|1464040-1464272|CRISPRCasFinder
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TAATGGTGTTGTTAATTGGAATGCAAAAGGG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	ACTTTAGTTTTAGACTTTGGAACAGTCGAGG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT	TATTTGAACGCTTAAAATCAAGAAAATATTG
TTTTAGTCCCTTTTTAAATTTCTTTATGGTAAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040612.1|WP_002858431.1|1459241_1460390_-|carboxynorspermidine-decarboxylase	unknown	unknown	gnl|CDD|273414
NZ_CP040612.1|WP_002858890.1|1462728_1463919_+|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl|CDD|223380
NZ_CP040612.1|WP_079264123.1|1455254_1458059_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|239153
NZ_CP040612.1|WP_002851537.1|1458058_1458250_-|twin-arginine-translocation-signal-domain-containing-protein	unknown	unknown	gnl|CDD|236534
NZ_CP040612.1|WP_002779488.1|1462056_1462278_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|224888
NZ_CP040612.1|WP_002851502.1|1458224_1458938_-|molecular-chaperone-TorD-family-protein	unknown	unknown	gnl|CDD|225916
NZ_CP040612.1|WP_002851546.1|1474569_1475019_-|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl|CDD|223854
NZ_CP040612.1|WP_002867064.1|1464840_1465731_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NZ_CP040612.1|WP_002797817.1|1464416_1464848_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NZ_CP040612.1|WP_002856113.1|1471413_1472019_+|dephospho-CoA-kinase	unknown	unknown	gnl|CDD|234620
NZ_CP040612.1|WP_002858889.1|1462278_1462725_+|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|223391
NZ_CP040612.1|WP_002851264.1|1454616_1455258_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319893
NZ_CP040612.1|WP_145599593.1|1460513_1462055_+|multicopper-oxidase-CueO	unknown	unknown	gnl|CDD|225043
NZ_CP040612.1|WP_002855997.1|1472015_1472765_+|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|234768
NZ_CP040612.1|WP_002855314.1|1468888_1470343_+|C4-dicarboxylate-transporter-DcuC	unknown	unknown	gnl|CDD|225611
NZ_CP040612.1|WP_100625615.1|1465727_1468682_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226044
NZ_CP040612.1|WP_002855427.1|1470363_1471353_-|phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
NZ_CP040612.1|WP_002851174.1|1453687_1454620_-|formate-dehydrogenase-subunit-gamma	unknown	unknown	gnl|CDD|130645
NZ_CP040612.1|WP_002868022.1|1472739_1473471_+|glucosaminidase-domain-containing-protein	unknown	unknown	gnl|CDD|225539
NZ_CP040612.1|WP_002867075.1|1473467_1474505_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP040612.1|WP_100625615.1|1465727_1468682_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	0	1158.9	71.3
NZ_CP040612.1|WP_002867064.1|1464840_1465731_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	4.5e-98	322.5	8.6
NZ_CP040612.1|WP_002797817.1|1464416_1464848_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	5.1e-59	192.3	1.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040612.1|WP_002858431.1|1459241_1460390_-|carboxynorspermidine-decarboxylase	gnl|CDD|273414	TIGR01047, carboxynorspermidine_decarboxylase, carboxynorspermidine decarboxylase. This protein is related to diaminopimelate decarboxylase. It is the last enzyme in norspermidine biosynthesis by an unusual pathway shown in Vibrio alginolyticus. [Central intermediary metabolism, Polyamine biosynthesis].	0
NZ_CP040612.1|WP_002858890.1|1462728_1463919_+|molybdopterin-molybdotransferase-MoeA	gnl|CDD|223380	COG0303, MoeA, Molybdopterin biosynthesis enzyme [Coenzyme metabolism].	6.1742e-140
NZ_CP040612.1|WP_079264123.1|1455254_1458059_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|239153	cd02752, MopB_Formate-Dh-Na-like, Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the major electron donor to the nitrate respiratory chain. Also included in this CD is the Desulfovibrio gigas tungsten formate dehydrogenase, DgW-FDH. In contrast to Fdh-N, which is a functional heterotrimer, DgW-FDH is a heterodimer. The DgW-FDH complex is composed of a large subunit carrying the W active site and one [4Fe-4S] center, and a small subunit that harbors a series of three [4Fe-4S] clusters as well as a putative vacant binding site for a fourth cluster. The smaller subunit is not included in this alignment. Members of the MopB_Formate-Dh-Na-like CD belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_CP040612.1|WP_002851537.1|1458058_1458250_-|twin-arginine-translocation-signal-domain-containing-protein	gnl|CDD|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	0.00441722
NZ_CP040612.1|WP_002779488.1|1462056_1462278_+|MoaD/ThiS-family-protein	gnl|CDD|224888	COG1977, MoaD, Molybdopterin converting factor, small subunit [Coenzyme metabolism].	1.67964e-11
NZ_CP040612.1|WP_002851502.1|1458224_1458938_-|molecular-chaperone-TorD-family-protein	gnl|CDD|225916	COG3381, TorD, Uncharacterized component of anaerobic dehydrogenases [General function prediction only].	0.00059716
NZ_CP040612.1|WP_002851546.1|1474569_1475019_-|DNA-starvation/stationary-phase-protection-protein	gnl|CDD|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	5.92874e-51
NZ_CP040612.1|WP_002867064.1|1464840_1465731_-|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.27175e-120
NZ_CP040612.1|WP_002797817.1|1464416_1464848_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.92184e-59
NZ_CP040612.1|WP_002856113.1|1471413_1472019_+|dephospho-CoA-kinase	gnl|CDD|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	8.14455e-71
NZ_CP040612.1|WP_002858889.1|1462278_1462725_+|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.09823e-44
NZ_CP040612.1|WP_002851264.1|1454616_1455258_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319893	cd16371, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	6.18245e-57
NZ_CP040612.1|WP_145599593.1|1460513_1462055_+|multicopper-oxidase-CueO	gnl|CDD|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	4.74333e-120
NZ_CP040612.1|WP_002855997.1|1472015_1472765_+|diaminopimelate-epimerase	gnl|CDD|234768	PRK00450, dapF, diaminopimelate epimerase; Provisional.	4.75008e-93
NZ_CP040612.1|WP_002855314.1|1468888_1470343_+|C4-dicarboxylate-transporter-DcuC	gnl|CDD|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	6.55616e-71
NZ_CP040612.1|WP_100625615.1|1465727_1468682_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP040612.1|WP_002855427.1|1470363_1471353_-|phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	0
NZ_CP040612.1|WP_002851174.1|1453687_1454620_-|formate-dehydrogenase-subunit-gamma	gnl|CDD|130645	TIGR01583, Formate_dehydrogenase_cytochrome_b556_subunit, formate dehydrogenase, gamma subunit. This model represents the gamma chain of the gamma proteobacteria (and Aquifex aolicus) formate dehydrogenase. This subunit is integral to the cytoplasmic membrane, consisting of 4 transmembrane helices, and receives electrons from the beta subunit. The entire E. coli formate dehydrogenase N (nitrate-inducible form) has been crystallized. The gamma subunit contains two cytochromes, heme b(P) and heme b(C) near the periplasmic and cytoplasmic sides of the membrane respectively. The electron acceptor quinone binds at the cytoplasmic heme histidine ligand. NiFe-hydrogenase and thiosulfate reductase contain homologous gamma subunits, and these can be found scoring in the noise of this model. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	4.78832e-90
NZ_CP040612.1|WP_002868022.1|1472739_1473471_+|glucosaminidase-domain-containing-protein	gnl|CDD|225539	COG2992, Bax, Uncharacterized FlgJ-related protein [General function prediction only].	1.02462e-101
NZ_CP040612.1|WP_002867075.1|1473467_1474505_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.51502e-33

Protein sequences

>NZ_CP040612.1|WP_002858890.1|1462728_1463919_+|molybdopterin-molybdotransferase-MoeA
MLMSYEESLKILHSHIKTYEKIEKIALTECLGRILAQDIKAPKNQPEFPTSAMDGYAIKFEDQDKPLKILGITPAGTMPQFSVQNGTCVKTFTGSLMSEGSDTLAPVENVRVENDTLFIEKKVPQAFAVRAVGENYKKDEILLKKGTKLNYSEIALLAELGFFHISVFIKPIVGVLSSGSEIKDLGEALENPAQIRSSNHIAIANLAKNLNCDTRVFPLLKDDEKATFSTLESALQSCDILVTTGGVSMGDFDFLKKAIKEYEIIIDKADIKPGRHIKIAKANEKFIIALPGFPYSAMVMFNLYAREILNSWLLQPKDYICKAFLQGSYKKKTPYLEFVACNIKFENGRILANLEGKKEGSSAIINNLNNKAALMVVPKECEILENESLVDIIFMP
>NZ_CP040612.1|WP_002858889.1|1462278_1462725_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MKHFTLYQGSLDIPKIYSQWYEFSKDKNCGALLTFCGIVREEGGIEALSFDIYEPLLKKWFDEWQKRVDFDGISLLFAHSIGDVAIHESSYFAGILSKQRKLGLKLLNEFVEDFKASAPIWKYDVINKERIYAKERSTKLCGAGLLKG
>NZ_CP040612.1|WP_002779488.1|1462056_1462278_+|MoaD/ThiS-family-protein
MVKVEFLGPINKENLELEVKNLKELKEILQKDESLKEWLELCAVSLNDEIIFDENTKLKDGDKIALLPPVCGG
>NZ_CP040612.1|WP_145599593.1|1460513_1462055_+|multicopper-oxidase-CueO
MNRRNFLKFNALTLASMGVAYANPMHDMHSMHKNHSINHDLDTSFINFAPKNLKLLDPKQFPQGEILKALPLLKNESKEKNIFRATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKLKEATTIHWHGVPVPPDQDGSPHDPILAGEERIYRFEIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALSHLKEKDLMISDLRLDENAQIPNNNLNDWLNGREGEFVLINGQFKPKIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKAIYKEELFLSPASRVEVLIDAPKDGNFKLESAYYDRDKMMVKEEPNTLFLANISLKKENVELPKNLKIFKPSEEPKEFKEIIMSEDHMQMHGMMGKSESELKIALASMFLINGKSYDLKRIDLSSKLGVVEDWIVINKSHMDHPFHIHGTQFELISSKLNGKVQKAEFRAFRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHEDLGMMGNLEVKE
>NZ_CP040612.1|WP_002858431.1|1459241_1460390_-|carboxynorspermidine-decarboxylase
MFYEKIQTPAYILEEDKLRKNCELLASVGEKSGAKVLLALKGFAFSGAMKIVGEYLKGCTCSGLWEAKFAKEYMDKEIHTYSPAFKEDEIGEIASLSHHIVFNSLAQFHKFQAKTQKNSLGLRCNVEFSLAPKELYNPCGRYSRLGIRAKDFENVDLSTIEGLHFHALCEESAGALEAVLKVFEEKFGKWIGQMKWVNFGGGHHITKKGYDVEKLIALCKNFSDKYGVQVYLEPGEAVGWQTGNLVASVVDIIENEKQIAILDTSSEAHMPDTIIMPYTSEVLNARILATRENEKISDLKESEFSYLLTGNTCLAGDVMGEYAFDKKLKIGDKIVFLDQIHYTIVKNTTFNGIRLPNLMLLNAKNELQMIREFSYKDYSLRN
>NZ_CP040612.1|WP_002851502.1|1458224_1458938_-|molecular-chaperone-TorD-family-protein
MGALMDLEKLRLARSLYYQCLGELFVFSFSEERLSKLQEYLKTMQECLFDENLKSNFDILLKHLDDENSIQAFFKEYDLLFLSLKNSIPTTFSYIEEGFENSNPLLCVRQILVKSKIRRNEKFFKESEDSVGFCLLLMSEFLRQNEDDLAKELFEKVINKSIDEFLGDVFMNKNANLYKEIASIASAFMEFERLCFEVEKPAKINSKKVQNDLSRSEFLRREANKQRRTREKSQGIS
>NZ_CP040612.1|WP_002851537.1|1458058_1458250_-|twin-arginine-translocation-signal-domain-containing-protein
MKNRREFLKKSAFALGAAGVLGSTTLALAKDEERKDLVKGKSKKKEVLFQRSANWENYYIKAE
>NZ_CP040612.1|WP_079264123.1|1455254_1458059_-|formate-dehydrogenase-subunit-alpha
MSSVGENIKLTRRSFLKMAALSSLATPLLARSETLREASADELKEAYEGSKKVKTVCTACSVGCGIIAEVQNGVWVRQEIAQDHPVSSGGHCCKGSDMIDMVRSHVRLKYPMKKENGEWKRISYEQALSEIGEKLAAYRKENPESVMFLGSAKLNNEQAYYIRKFAAFFGTNNVDHQARIUHSATVAGVANTFGYGAMTNHLGDIQRSKCIIIIGANPAVNHPVGFRHFLKAKEKGAKLIVVDPRFTKSAAKADIYARIRPGTDIAFMYGMLKIIFDEGLEDTKYLDERVFGIDKIREEAAKWTVEEVENVTGISKELLVQITHEVAKNKPTTLIWAMGLTQHTVGTSNTRLAPIVQMVLGNIGKFGGGVNILRGHDNVQGASDMACLSENLPGYYPLNEATWRYYAKIWGVDYEWLLGNFVSKDWMHKTGLSLARWWVAALNGKDGNDAIDNAGTPLKALVVMGNGITSTAQQVKVKEGLEALELLVLADPFVNEAGIIAERKDGIYLLPAATQFETSGSVTATNRSGQWRFKVVDPLYESMEDQEILFELAKKLGFYEDFTKTLRDEKGEIVWPENATREIAKAVRSIGLNGWSPERLKKHTLYWDKFDEVTLEGKDEVAGEYYGLPWPCWSDKHPGSPVLYNTDIEVAKGGMGFRNNFGLEYEGESLLAKNAPLNSPIDTGYPQITKDNIEKVLGITLSAQEKEKMGSTWSYDDSNIIATKCIEKGIVPYGNAKARAVVWTFKDKIPLHREPLHSPRNDLVQKYPSFEDQKALYRVDTKFVSVQQAKDYSKEFPLNLVTARLVNLNGAGMENRASMYLTRLTPEMFCEINPELAKEQDIKAGDMIWVHSPEGTKIHVRVKVNPGVAKDMIFLPFHFTGVMQGVDLTHNFPEGTKPYASGESANTVTNYGYDIMCQIPETKGGLCRISKDGK
>NZ_CP040612.1|WP_002851264.1|1454616_1455258_-|4Fe-4S-dicluster-domain-containing-protein
MSKVNFANLEKERLKFFCDNERCIDCNGCAVACDEAHELPIHIRRRRVITLNEGIQGKEVSTSISCMHCDDAPCSIVCPVDCFYIRADGIVLHDKEICIGCGYCLYACPFGAPQFPKDSVFGNKGIMDKCTMCAGGPEATNSEKERELYGQNRIAEGKVPVCAAMCSTKALLVGESSKIEEIYHNRLMNRNYGIPNPSESLEWKIAYTGKERL
>NZ_CP040612.1|WP_002851174.1|1453687_1454620_-|formate-dehydrogenase-subunit-gamma
MRKVFVTLLLSVVSLFAYGSERMGQDTQIWDFHRITNIPNYDTFGKLWTTLQGEYIATIALIAVIAVLSAFALHYMVIGPKQFSHDGKKIYAFTLFERLFHFIAAISWVILVPTGFVMMFGEVFGGGVFVRVCKNLHAFATILFIISIIPMFLCWIKRMLPASYDIRWMMIVGGYLSKIKRPVPAGKFNFGQKSWYYIAVFGGFLMIITGGFMYFLDFNSTAIQGLFGLTQIELLRISAIVHNFLGIVCAVFFGVHIYMAVFAIKGSIHSMISGYKEEEEVYILHSYWYKELSNKKQIEPSFSYDPNVKI
>NZ_CP040612.1|WP_002797817.1|1464416_1464848_-|CRISPR-associated-endonuclease-Cas2
MIEDKFMRVLLMFDVPTKSKKEQKLASKFRNNLIKLGYFMLQFSVYMRICKGLSSAKSSIENVKKILPPYGNVRALIITEKQFDKMELLLGGIVFNEKVNNETNLTLFDIDSHGEFKYKNSNNEEIQINKKQEKYHQQNLFEF
>NZ_CP040612.1|WP_002867064.1|1464840_1465731_-|type-II-CRISPR-associated-endonuclease-Cas1
MSYDEAFKTLLISSNAKLNLELNHLVIKQDENIAKLFLKDINIIVLESLQVSLSSALFNAFARHKIILLTCDETHSINGVFTPFLGHFQSAKIAKEQMNVSAQKKAILWQKIIKNKILNQAFVLKKHNKIGQSNELINLAKKVSLNDSKNIEAVAAALYFKTLFGVSFSRDELCFENSALNYGYAIIRACIIRAVCISGLLPWLGIKHDNIYNSFALCDDLIEVFRASVDDCVLKLKGESEFLSKDDKRALIGNLQSKINFDGQNYPLNRAINHYVANFKNALLYEDELKIVKFDD
>NZ_CP040612.1|WP_100625615.1|1465727_1468682_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MARILAFDIGISSIGWAFSENDELKDCGVRIFTKAENPKTGESLALPRRLARSARKRLARRKARLNHLKHLIANEFKLNYEDYQSFDESLAKAYKGSLISPYELRFRALNELLSKQDFARVILHIAKRRGYDDIKNNGDEEKGKILKAIKQNEEKLVNYQSVGEYLYKEYFQKFKENSKEFINVRNKKESYERCITQSFLKYELKLIFQKQREFGFSFSKKFEEEVLSVAFYKRALKDFSHLVGNCSFFTDEKRAPKNSPLAFMFVALTRIINILNNLKNTEGILYTKDDLNALLNEVLKNGTLTYKQTKKLLGLSDDYEFKGEKGTYFIEFKKYKEFIKALGEHNLSQDDLNEIAKDITLIKDEIKLKKALAKYDLNQNQIDSLSKLEFKDHLNISFKALKLITPLMLEGKKYDEACNELNLKVAINEDKKDFLPAFNETYYKDEVTNPVVLRAIKEYRKILNALLKKYGKVHKINIELAREVGKNHSQRAKIEKEQNENYKAKKDAEIECEKLGLKINSKNILKLRLFKEQKEFCAYSGEKIKLSDLQDEKMLEIDHIYPYSRSFDDSYMNKVLVFTKQNQEKLNKTPFEAFGNDSTKWQKIEVLAKNLPEKKQKRILDKNYKDKEQKDFKDRNLNDTRYIARLVLNYTKDYLDFLPLSDDENTKLNDTQKGSKVHVEAKSGMLTSALRHTWGFSAKDRNNHLHHAIDAAIIAYANNSIVKAFSDFKKEQESNSVELYAKKISELDYKNKRKFFEPFSGFRQKVLDKIDEIFVSKPERKKPSGALHEETFRKEEEFYQSYGGKEGVLKALELGKIRKVNGKIVKNGDMFRVDIFKHKKTNKFYAVPIYTMDFALKVLPNKAVARSKKGEIKDWILMDENYEFCFSLYKDSLILIQTKDMQEPELVYFNAFTSSTVSLIVSKHDNKFETLSKNQKILFKNANEKEVIAKSIGIQNLKVFEKYIVSALGEVTKAEFRQREDFKK
>NZ_CP040612.1|WP_002855314.1|1468888_1470343_+|C4-dicarboxylate-transporter-DcuC
MPIFMICSTLLAVIVVTYYILKKYNPIFVFFLSGIILLIFAFYITGTPIPKAPSREHASFLNVLLDSYAFITATFKSQLSGVGLIIMSVAGFAAYMKHINASAKLAFLANKPLGKIKNKYLILSGTFVVGMALKIVISSYAGLLLLLLACIYPVLISLKIRPITAVCVLSLIALDYGPKDGNSINMADMVGQSDNVVGLFLNYQIYSVIAYVVVIAILIPFYFAWIDKRDKEKGVLNDEVEIPQIIDPKCPTFYILFPWLPVVFLFTAYFFTIKLDVVTANFVSISLVFLVEFARHRNARKLGEDMMVILKAMAEIFISVVSIIIAAGVFAEGIKALGGVNILANAVSNLGTGNFAWFGILLSIAILSFLVYFATVIMGSGIAAFNAFGKLAPDIATKLDVAPITLVLPIEIASCLGRAASPIAGGIIALAGFAKVAPMDIIKRTTPLLLIAMLVNVLVAFYLAQTNPLPKEQNTTKIELKIQK
>NZ_CP040612.1|WP_002855427.1|1470363_1471353_-|phosphoribosylformylglycinamidine-cyclo-ligase
MKISYEDAGVSIDNGNAFVEAIKPLVKETFNDNVVGGIGSFAGAFRMPSGFKKPVILGATDGVGTKLRLAIDAKKYDTIGQDLVAMCVNDLICNFATPLFFLDYYATAKLEVEVAKAVVSGIAKGCKMANCALIGGETAEMPGMYAKDDFDLAGFAVGMAEEDEIDRSKFVKNGDILLALPSSGLHSNGYSLARKVLFESLKLKFDDKIEGKNLIDILLEPTRIYVRDFLTLKPYISALAHITGGGLVENLPRVLPRGMGATIRKHHLKTPEIFYTIGQAVEESEMYRSFNMGVGLVMVVDPSNVSKVLENSDAFIIGEICINEGIVLE
>NZ_CP040612.1|WP_002856113.1|1471413_1472019_+|dephospho-CoA-kinase
MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHEILDENALELEKIFSPFSLKNLLTKEKKIDRKILGKIVFNNKEAKKTLENFTHPKIRAKILEQMQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGKM
>NZ_CP040612.1|WP_002855997.1|1472015_1472765_+|diaminopimelate-epimerase
MKFYKYCASGNDFVITNADRKEDRSALAKELCNRYEGIGADGFIVILPHEKYDFEWEFYNNDGSRAAMCGNGSRAAAHFAHHINKINPNMSFLTGAGVIKAKVNQDKVEVSLGKIKSVQNTFEELGKTWQLCNTGVPHLVHFCQNLDEFDTMLCQKMRQKYNANVNFVKILDENHLKVRTYERGVEDETLACGTGMGACFYLAFLNKKVQNKVKITPKSGEEVGFAYKNEELFFEGKVKYCFEANYNFS
>NZ_CP040612.1|WP_002868022.1|1472739_1473471_+|glucosaminidase-domain-containing-protein
MKPIIIFLSLFLIPLFADDLKSGFGEEYYKLDIDQKRQIFFIKMNEMFDQSFKKIEQERAFIEAFFKDAYKTGFRTSNQINLEKLITIKNKYRIENLYDFAEYKKRIQKIPKSMGIAQALVESATGTSRFAREANNLFGEWTWGEKGLIPDLRHPDKKHKIKIFDSLQDSVDSYVLNLNRHFAYEKFRDARAKFESEGKEITGLEAIKTLDSYSERKGYYINLITKIIKRYNLEKYDTNSNNT
>NZ_CP040612.1|WP_002867075.1|1473467_1474505_-|ATP-binding-protein
MKVLNFFYENHPKFEVSYERKNQISKPNIIIKGPRFCGKKTLIFNFLSQFKASEILFLDLYDTRFEKQSLERLADFLNENLQIKILCLYNLDFIPNLEKIKIPIILSTNIKDLNINGFEELELDYFDFEEFISVSKKNLPINNLVGLFLQSGRSKFGEKNILLRQSFTLLELEILKYLALNLGQQISISKIFIELKKRLKTSKDSVYQAIKKLENTYVIYTLKHDEKKLQKIYFKDFGLRNNLCISKDFSHLFENLVLSELFKFKEEFFYNKYFNFYSQISKIAYISSPTLDIDLIKLRAKKILPKALELGIFHVIFITLSSEDNFFEQGVKFEVISFDKFSLGF
>NZ_CP040612.1|WP_002851546.1|1474569_1475019_-|DNA-starvation/stationary-phase-protection-protein
MSVTKQLLQMQADAHHLWVKFHNYHWNVKGLQFFSIHEYTEKAYEEMAELFDSCAERVLQLGEKAITCQKVLMENAKSPKVAKDCFTPLEVIELIKQDYEYLLAEFKKLNEAAEKESDTTTAAFAQENIAKYEKSLWMIGATLQGACKM

Crispr_ID: NZ_CP040612_2

• CRISPR_ID: NZ_CP040612_2
• CRISPR_location: 1490601-1490713
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_CP040612_2

Consensus_repeat	Method
TAGTTTTCTTAACTTTGGTAGTATAAAACAAGAAAA	CRISPRCasFinder

spacers of NZ_CP040612_2

>2.1|1490637|41|NZ_CP040612|CRISPRCasFinder
TTCAAATAAGTGATTAAAAGAATGTTTGGTTTTAAATTATT

CRISPR arrays and Neighbor proteins around NZ_CP040612_2

CRISPR arrays

The CRISPR arrays of NZ_CP040612_2

>merge|NZ_CP040612|2|1490601-1490713|CRISPRCasFinder
TAGTTTTCTTAACTTTGGTAGTATAAAACAAGAAAATTCAAATAAGTGATTAAAAGAATGTTTGGTTTTAAATTATTTAGTTTTCTTAACTTTGGTAGTATAAAACAAGAAAA

>NZ_CP040612|2|2|1490601-1490713|CRISPRCasFinder
TAGTTTTCTTAACTTTGGTAGTATAAAACAAGAAAA	TTCAAATAAGTGATTAAAAGAATGTTTGGTTTTAAATTATT
TAGTTTTCTTAACTTTGGTAGTATAAAACAAGAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP040612.1|WP_002868369.1|1481137_1481947_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225544
NZ_CP040612.1|WP_145599592.1|1486940_1488020_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176186
NZ_CP040612.1|WP_002871957.1|1507085_1508573_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|273903
NZ_CP040612.1|WP_002851227.1|1485477_1486056_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|225158
NZ_CP040612.1|WP_002872144.1|1484548_1485445_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NZ_CP040612.1|WP_002871958.1|1505707_1507096_-|NADH-quinone-oxidoreductase-subunit-N	unknown	unknown	gnl|CDD|223939
NZ_CP040612.1|WP_145599591.1|1488155_1490465_+|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|226581
NZ_CP040612.1|WP_002872143.1|1483586_1484552_+|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NZ_CP040612.1|WP_002872145.1|1486155_1486503_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_CP040612.1|WP_002856292.1|1496068_1497553_+|type-I-restriction-modification-system-subunit-M	unknown	unknown	gnl|CDD|280533
NZ_CP040612.1|WP_041160302.1|1493691_1494879_+|restriction-endonuclease-subunit-S	unknown	unknown	gnl|CDD|341182
NZ_CP040612.1|WP_002873812.1|1498903_1500079_-|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP040612.1|WP_002872141.1|1482088_1482856_+|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|224457
NZ_CP040612.1|WP_010891944.1|1501288_1503277_+|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NZ_CP040612.1|WP_145599589.1|1498426_1498846_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380361
NZ_CP040612.1|WP_002858055.1|1500778_1501210_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133384
NZ_CP040612.1|WP_002871959.1|1503319_1505686_-|paralysed-flagellum-protein	unknown	unknown	gnl|CDD|185387
NZ_CP040612.1|WP_002872142.1|1482865_1483606_+|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl|CDD|224960
NZ_CP040612.1|WP_079263661.1|1480372_1481092_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|227008
NZ_CP040612.1|WP_004315572.1|1500447_1500771_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP040612.1|WP_004315572.1|1500447_1500771_+|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	5.9e-20	66.5	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP040612.1|WP_002868369.1|1481137_1481947_+|substrate-binding-domain-containing-protein	gnl|CDD|225544	COG2998, TupA, tungsten ABC transporter substrate-binding protein [Coenzyme metabolism].	4.10269e-146
NZ_CP040612.1|WP_145599592.1|1486940_1488020_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.17594e-164
NZ_CP040612.1|WP_002871957.1|1507085_1508573_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|273903	TIGR01972, NADH-quinone_oxidoreductase_subunit_M, proton-translocating NADH-quinone oxidoreductase, chain M. This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport].	1.21035e-158
NZ_CP040612.1|WP_002851227.1|1485477_1486056_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|225158	COG2249, MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only].	3.5555e-52
NZ_CP040612.1|WP_002872144.1|1484548_1485445_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	7.26252e-10
NZ_CP040612.1|WP_002871958.1|1505707_1507096_-|NADH-quinone-oxidoreductase-subunit-N	gnl|CDD|223939	COG1007, NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion].	2.0868e-109
NZ_CP040612.1|WP_145599591.1|1488155_1490465_+|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	8.37479e-120
NZ_CP040612.1|WP_002872143.1|1483586_1484552_+|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	9.63337e-150
NZ_CP040612.1|WP_002872145.1|1486155_1486503_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.45165e-36
NZ_CP040612.1|WP_002856292.1|1496068_1497553_+|type-I-restriction-modification-system-subunit-M	gnl|CDD|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	5.59126e-64
NZ_CP040612.1|WP_041160302.1|1493691_1494879_+|restriction-endonuclease-subunit-S	gnl|CDD|341182	cd17293, RMtype1_S_Ppo21ORF8840P_TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Paenibacillus polymyxa SQR-21 SQR21 S subunit (S.Ppo21ORF8840P) TRD1-CR1, Nitrosococcus halophilus Nc4 S subunit (S.NhaNc4ORF3964P) TRD1-CR1. The recognition sequences of Paenibacillus polymyxa SQR-21 SQR21 S subunit (S.Ppo21ORF8840P) and Nitrosococcus halophilus Nc4 S subunit (S.NhaNc4ORF3964P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This superfamily contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	1.51358e-71
NZ_CP040612.1|WP_002873812.1|1498903_1500079_-|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.59639e-55
NZ_CP040612.1|WP_002872141.1|1482088_1482856_+|LamB/YcsF-family-protein	gnl|CDD|224457	COG1540, COG1540, Uncharacterized proteins, homologs of lactam utilization protein B [General function prediction only].	3.05911e-153
NZ_CP040612.1|WP_010891944.1|1501288_1503277_+|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.41361e-38
NZ_CP040612.1|WP_145599589.1|1498426_1498846_-|cupin-domain-containing-protein	gnl|CDD|380361	cd02233, cupin_HNL-like, Granulicella tundricola hydroxynitrile lyase (GtHNL) and related proteins, cupin domain. This family includes archaeal, eukaryotic, and bacterial proteins homologous to hydroxynitrile lyase from Granulicella tundricola (GtHNL), a novel class of HNLs that does not show any sequence or structural similarity to any other HNL and does not contain conserved motifs typical of HNLs. HNLs comprise a diverse group of enzymes that vary in terms of their substrate specificity, enantioselectivity and the need for a co-factor. In plants, they catalyze the reversible cleavage of cyanohydrins, yielding HCN and aldehydes or ketones. Also included in this family is TM1010 from Thermotoga maritima, a protein of unknown function. Some but not all members of this family have N- or C-terminal carboxymuconolactone decarboxylase domains in addition to the cupin domain. Members of this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.80218e-43
NZ_CP040612.1|WP_002858055.1|1500778_1501210_-|MerR-family-transcriptional-regulator	gnl|CDD|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	3.10906e-48
NZ_CP040612.1|WP_002871959.1|1503319_1505686_-|paralysed-flagellum-protein	gnl|CDD|185387	PRK15490, PRK15490, Vi polysaccharide biosynthesis glycosyltransferase TviE.	0.0030321
NZ_CP040612.1|WP_002872142.1|1482865_1483606_+|5-oxoprolinase-subunit-PxpB	gnl|CDD|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.62638e-105
NZ_CP040612.1|WP_079263661.1|1480372_1481092_-|ABC-transporter-permease	gnl|CDD|227008	COG4662, TupA, ABC-type tungstate transport system, periplasmic component [Coenzyme metabolism].	9.41671e-96
NZ_CP040612.1|WP_004315572.1|1500447_1500771_+|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.42976e-16

Protein sequences

>NZ_CP040612.1|WP_145599591.1|1488155_1490465_+|DEAD/DEAH-box-helicase-family-protein
MQNLYSEDDTRVKLIDTKLYASSWKEENIIRNYYFTDGRKLIGNKRAERKFADYLLKFQNNNLAIIEAKKQNKDALDGLSQGIEYAKTLNVPFVYSTNGDKIYEYDLRVSRGEYIENFPSPNELFQRVYGNLKEWQYKLLTQRELYIPQKTLRYYQKIAVDKVIEALINGKDRILLTLATGTGKTTIAFALCYRLLEARWNKENKDQKPKILFLCDRVSLRDQALGEFNAVESDCKVISAEEIRKNDGKIITNANVFFGIYQSLAANSKDQENTQEEQESKFYLQYPKDFFDLIIIDECHRGGANEEGSWRAVLEYFSYATQLGLTATPKKEENIDTYEYFGESVYDYSLKSGIEDGFLTPYKVKLIKTTLSDGYTYNPDDLIQGELEKGFYKQSEFERNIFLPNYNDFIAKKILELINPMDKTIIFCVNQAHANEVKRAIDKYKSVKRDDYCVRVTSNEGKIGLDYLKLFQDNDKSYPVILTSSKMLTTGVDAKNVRNIVLLANIGSMVEFKQIIGRGTRVYEGKDFFTILDFVGATKLFYDPKWDGEKIEELKEQDEKEKITKEHIKQTKEESKEKKSVTIHLKGTKLKVLDITTTYVGAQGKPLSTKEFLEFLIGKLGEYYDDEAKLREIWSDQKNRERFLKALANDGVDEDALKDLREIFQKDCDIYDVLAHLSFNAEIKTRQERVLQVENGEFLKRFQKEKAIKFIEFLLGRYQQYGIKDFDDGLKPLIELSSLGNVRELADEFGGLEILKQSFDDLQREIYLN
>NZ_CP040612.1|WP_145599592.1|1486940_1488020_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MDSKIFLENGRIQSKGYAMLSKDAKFTAFEFSRHAIGDNDILIKILYAGICHSDIHTARSEWGEAVYPCVPGHEIAGEVIAVGKNVSKFKVGDYAGVGCMVNSCGECEACKKSQEQFCEKGQTIYTYNSCDIFHDNENTYGGYSNNIVVSEKFAVCVPKNAPMEKVAPLLCAGITTYSPLKFSNIKAGSSVAVAGFGGLGMMAVKYAVKMGAKVSVFARNENKKADALAMGVSSFYTSTDKNAVKERFDLIISTIPTPYNPAIYLDLLKFGGEMAIVGLPPVEDKVNIGINELVHKAGKKVYGSLIGGIAETQEMLDFSLKHGIYPETELITPQEIDKAYENLTSGKAKFRYVIDMTKE
>NZ_CP040612.1|WP_002872145.1|1486155_1486503_+|helix-turn-helix-transcriptional-regulator
MTKENSPCNFEECGFNYTLALINGKYKMSILYCLFRYEIMRYNELKRFLSSISFKTLTNTLRELENDGLIIRKEYAQIPPKVEYSLSKRGQSLIPILQAMSKWGKKDKKGKKCLN
>NZ_CP040612.1|WP_002851227.1|1485477_1486056_-|NAD(P)H-dependent-oxidoreductase
MKNILLLNGAKEFGNSKGQLNLTLHNHALEILKTLGYEVDQTHIDQGYDPKEEIQKFIKADAVIYQMPAWWMGEPWIVKKYIDEVFGLGAGVLFKNDGRTHENPSKNYGKGGLDHGKKYMFSLTWNAPLEAFNDKNEFFEGKGVDMVYWHLHKAHEFIGMKALPTFMCNDVVKNPQVEKYLNEYELHLKKIF
>NZ_CP040612.1|WP_002872144.1|1484548_1485445_-|DMT-family-transporter
MTRTKYLYILLVIAMFLWGSSWPTSKILANYTDTSIITFWRFFFVVLGSFFVLNFLKIPLKIEKTALKWVLIAGVLNGLYAFVFFIAIKHGLAGKGGVLVTTMIPIFSYLIFMIAIFFQKNKKSTHKITKSEILGLFLGLLSGFCLLNLGSLEDLFGKFNILFLTCSFIWALMAVFNHKAKGAHPLAINFYINLISVLMFSWVLFDVKSYEIFHFKFKFWISMFVVAFLSTIIGTSIYYYGIHILGSVKANSFVLITPASALICSYFILDEVPNALTLLGCALAIGAIYFINIYGKKA
>NZ_CP040612.1|WP_002872143.1|1483586_1484552_+|biotin-dependent-carboxyltransferase-family-protein
MSIKIIEASINSSLQDFGRKKFAKFGIARSGAMDEDALRMANILLGNKQDEAGIELCLKGGKYEFLDENYFVLSGAEFEAKLDNQKIKTCKVYQANKGDILELDLAKIGFRGYLCVAGGFEVKSFLNSKSSDAKMGAGVFEGRALQKDDILNTHNTFIPFNLEARECENPLFKSPKEPIIRVILGTNEDAFTQKGIETFLNTTYKVGLKSDRMAIYAESSESIEHKNSADIISDPAVFGSIQVPKNGIPIILMAGRQSTGGYTKIATVIENDLSLLAQAKLGSSFKFQSISMQEALELYKQREMKFKAMDQKINLDFENLI
>NZ_CP040612.1|WP_002872142.1|1482865_1483606_+|5-oxoprolinase-subunit-PxpB
MFSVHFSGSKALLLRFEQEISPQINAYVLSTEQRIQKALKEGEIYGIDELVSTYASLLIYFNPCVLSLNSLLDFLEKIKKDIKLTEQNSSLCIEVPLCYDEEFGLDLEFVCKHNQISKEELISLHTKPYYLVFMLGFMAGFPYLGGLDERLFTPRLSSPRAKIEAGSVGIADKQTGVYPISSPGGWQIIARTPLEFFDKEDEKNPTLLKAGMFLKFKAISKDEFFEIQEQVAKKVYQKEIYEYKNH
>NZ_CP040612.1|WP_002872141.1|1482088_1482856_+|LamB/YcsF-family-protein
MFKVDLNSDLGESFGAYKMGMDEEILKFVSSVNVACGFHAGDPCVMDETLNLAKQNGVCIGAHPSYPDLLGFGRRNMQISFEEAKNYALYQLGALFGFAKAKGMKIQHFKAHGALYNMAAIDENLALALCEAVASFDENIIFLGLGNSAMNEAAKKKGLRYANEVFADRAYNDDGTLVSRKLEGALIHDENLAIKRVIKMIKESKVTSINGKEIDLKADSICVHGDNAKALEFVKKIKENLKKEQIQICALENFI
>NZ_CP040612.1|WP_002868369.1|1481137_1481947_+|substrate-binding-domain-containing-protein
MKKIISLALALALSASAAELKMATTTSTDNTGLLDALKPLYKKESGNTLKWVAVGTGAALKMGEDCNADVLFVHSPKAEKEFMKKGFGVDRTPVMYNDFIIIADKSLASKFKGKNLKESLELIKNEKLTFISRGDKSGTDNKEKSLWKNLGGVPEKQSWYQQSGQGMLASIKIAEEKKGVILTDRGTYIKYEANEKGKPNLVIVNEGDDSLKNFYSVIATNPKHCKNVNYTEASKFIKWVTSDKTLNFIADFKLLNKPLFVIDAKTRKD
>NZ_CP040612.1|WP_079263661.1|1480372_1481092_-|ABC-transporter-permease
MLKLLILKRIFLDYIFDGFKQALFLLFNADESVISAIKTTLLSSSISIVLALLIGFPLGFILGFFDFKFKYFIKLIIDTSLSFPTVAVGLILYALISSRGPLGEFGLLFTIKALILGQFILALPIVIALFSNLIENMNKKHFLLIKSFHLSPLKLVLTMIYELRFALISVVALAYGRIVAEVGVAMIVGGNIKYDTRTITTAISLETNKGEFASGIALALVLILIAFCLNFITHKLKRT
>NZ_CP040612.1|WP_041160302.1|1493691_1494879_+|restriction-endonuclease-subunit-S
MQNKMTNLPQGWKVKTLSEISEIVTGSTPSKSNLDFYGKDYPFFKPSDFEQGYFLENAGDNLSKLGFDKARQLPPKTILVVCIGSLGKVALTRVIGSCNQQINAIIPHKNIIAEYIYYYCISSKFQSILFSKAPQTTLAILNKTEFSKLEIIYPKDIKEQERIVRILDESFANIDESIKILEQDLLNLDELMQSALQKAFNPLKDNAKENYKLPQGWEWKSLEEISENISAGGDKPKNCTESKTAKNQIPVYANGVNNNGLVGYTDKATIIKPSLTISARGTIGFVCIRKEPYFPIVRLISLIPCENILCLHYLYFCLNFFIAKGEGSSIPQLTIPKFKSLQIPLPPLKEQEQIAKHLDFVFEKTKALKELYTKELKDYEELKQSLLNKAFKGEL
>NZ_CP040612.1|WP_002856292.1|1496068_1497553_+|type-I-restriction-modification-system-subunit-M
MQNKIDKITDILRRDDGISGAMHYTEQIGWILFLKFLDDYETNLKDLAFLDGKDYKSILQEKFSWSVWAAPKKDGKLDVKNALSGSDLLEFVNKELFPYLKNFKNNDDFKSIEYKIGGIFEFIDNRIANGHTLREVINIIDEISFNKEDEVFALGEVYEKLLKDMGSDGGNSGEFYTPRPLIKTMVEVIDPKPKERIYDPSCGSCGFLVESFLHILYKDRTKGKKANLSVEELEFLKNDALFGKEKTPLSYAMGVMNMILHEISSPNIIKTNTLSKKITDITEKDKYEVILANPPFGGKEKEQIQENFPIKSNATELLFLQHILKSLKNNGRCAIIVPEGVLFQNSNAFVSVKKDLLDDFNLECVLSLPSGVFLPYSAVKTNVLFFSKGKKCICEGDGVYYYELIPPYKLTKNKPLEYAHFKEFLKCYKERKITANSWLVSKKELEERNYDLSAKNPNVKEEKILRTSEEILNSLEENLKTQQKYLNELKSILK
>NZ_CP040612.1|WP_145599589.1|1498426_1498846_-|cupin-domain-containing-protein
MQELEKAGIHGSFKGDSKFFSKNVKVSMMFKSNEWRNFSGALVEFEVSARSAWHTHPQGQTLIVTEGEIITKVPGQKAFIAKKGDAISCPIGVKHFHGATNTSSGAHIALTGEKEGKNVEWLELVSDEEYENALKEARE
>NZ_CP040612.1|WP_002873812.1|1498903_1500079_-|MFS-transporter
MKNLNKASNAQIILVFCLGVFGILSTELGMMGIIPIVSQNFSVSISDAGWCVSIFALVITFCAPIVPLLCANFNPKKLMLICLAVFILSSLTSAFVGEFWQLLILRAIPAFFHPIYIALALSMVTNLVEDKKEIPKATAKIFAAVSAGMVLGVPMTSYFGGNFSFKMAMLFFVFLNTLSFIATLFFVPDFKKVNSVKISKQLLILRYPLLWISILCVICINAGIWGFYSYFSDFLHSVGKMNFTLISIVLAIYGFSNIIGNYIAGKTLVKNANFTLILTPLIMIGFYILLFSFYSEIILIIFAFILGILVGVMNNGTHFMISYPFPKAANFSNGLFISVANIGLSTGTAICGLVISLSDTRYIIVNTIVLLILGIIMIFVRSRIEKMKLRF
>NZ_CP040612.1|WP_004315572.1|1500447_1500771_+|winged-helix-turn-helix-transcriptional-regulator
MQKFLTIISAINDESRVLILYHLLRYKELCVCDLQELLNMGQSRLSRHLKILKDAGFLYVRRQGTWAYYGINDELLKLHLDLFENIKNLELKNAIKKNENIITQICP
>NZ_CP040612.1|WP_002858055.1|1500778_1501210_-|MerR-family-transcriptional-regulator
MAYTIKKVEKETKISAHTLRFWAKKGLFPFVQKDENSVKYFSKSDIEWVKWIEWLRISGMPIEQIKHYIKLCSLGIKTAKERQEMLKQTKKKLQNQIKTLKESEKVLSKKIKIYEEMLANEVDGFNPESKDYQPCDKLHKFKG
>NZ_CP040612.1|WP_010891944.1|1501288_1503277_+|methyl-accepting-chemotaxis-protein
MLKITKIKRKIMNSIKIKLSLIANLIAIFALIVLGIVSFYFTKTSLYESTLKNQTDLLKVTQSTVEDFRSTNQSFTRALEKDIANLPYQSLITEENIINNVGPILKYYRHSINALNVYLGLNNGKVLLSQKSNDAKMPELRDDLDIKTKDWYQEALKTNDIFVTPAYLDTVLKQYVITYSKAIYKDGKIIGVLGVDIPSEDLQNLVAKTPGNTFLFDQKNKIFAATNKELLNPSIDHSPVLNAYKLNGDNNFFSYKLNNEERLGACTKVFAYTACITESADIINKPIYKAAFIQAIVVIIVVVFSVILLYFIVSKYLSPLAAIQTGLTSFFDFINYKTKNVSTIEVKSNDEFGQISNAINENILATKRGLEQDNQAVKESVQTVSVVEGGNLTARITANPRNPQLIELKNVLNKLLDVLQARVGSDMNAIHKIFEEYKSLDFRNKLENASGSVELTTNALGDEIVKMLKQSSDFANALANESGKLQTAVQSLTTSSNSQAQSLEETAAALEEITSSMQNVSVKTSDVITQSEEIKNVTGIIGDIADQINLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANTNLLVQSINDMAESIKEQTAGITQINDSVAQIDQTTKDNVEIANESAIISSTVSDIANNILEDVKKKRF
>NZ_CP040612.1|WP_002871959.1|1503319_1505686_-|paralysed-flagellum-protein
MRILFLILLSFLNAFAFELVLNTGRENNQAFAVLHASNDLEFTCQKFITEAKVHFECDIVGMVDNKLKDQSFSAFDLKFIQEAQKIKMIILPKIQARMFDTSQNIYIDKELSSSSSHKSKAFTFIFTPELAPIKDYDGLDFNINFPHESLPYVGALDLNSDPVVIPQSADINTYLRIKKEYDKANYNQVVIDAQSAINRYRGSVFTSEFILYKLRAQNKLYTQDPSMRDQQILEKMIDDAKNWTRTFTSDKNFSEVLHIMLRTYIALAQRADVEYTMSILDNEQPNNYFTQLSKLDYADYIYNLNEKEKAVNIYENTYFNTKNLDLAARAAMSLAKNLLSNEQVNKAIEYINTILKANPEYFGKDIPRSLELAKLFNQKGQFDISASIYEDAFAKMSKLDPSYEETLKDLALVLSHANRSSDAKKYLDLYMDDYLDGKYLDEIKKASDEVFFALGDNNASFLHQRYTDLMKQYANKDENIANKALDEDVALYYKEGNFSAILAYKDLIESKKIPNATQFLEKAAINDLKNAIKADNCINAANIFMHFSAYDIGQKIENKKQMLACLIRTSNVEQALDYIDKNYNEDSIFYGLQKASILFDNKQYPQVIKISKDIANSRILKSDDENFKAYYLQFLSLLRLNDYNQAIKILQILESFPMNFSMVEAYDALLSYANDHNMQTTILTYAPKAIDYQNFKGINLFSPNLEFIYLDALTKINKNEESLAVLTDLLKLKLSDEDRARALYIQALTYERMQNIQAEKESLKQCLEIKSASNWQNLCKSKNQILNQ
>NZ_CP040612.1|WP_002871958.1|1505707_1507096_-|NADH-quinone-oxidoreductase-subunit-N
MLNNFLNLELLNISLSYPFLFLITTAIVLLLCSGFWKFHRSFYIGISSLSLIVSAFLILNNANAQGLEAKAFLATLNNDIVSFYASLVILCFSFLYLLMQKEENQGEFYALFLFMIASLLLMVSSSNLVLIFIGLESSSLALYTLIAMRGSDNAISSAIKYFSVAAVGAGFFVMAVAFIYLKTGTLDLSANLALKNEFQKDPMLLGAGVMIFVLCAIKLSLAPFHFWLKDVYYAAHTNLVAFISVVPKVAMLVVVIRLFDFLNNTGFEYIIIVLAIFSMLIGAFAALSQNNIKKMFAYSSVVHSSLVLVACIPLLKEQNFDGILLAIFGYWTLFAFANYAVFMILSNYENNSYESLNGLLVKKPLIAFCLSISVLSLAGIPPFGVFWGKFMILNTAILNGYWYLVLFVALSSVIMLYAYLKILIHALFMKNDRVHNIKFSFIQNFILAFCVCVSTFVILLML
>NZ_CP040612.1|WP_002871957.1|1507085_1508573_-|NADH-quinone-oxidoreductase-subunit-M
MLNYLIFFPLISAFVVLLLNRGGIKVFSVVVSFMILALNLDIFADFLQGTSFDYNLSFKILKFFSFHVGVDSIALILMLLSSLMIFLSFLFLKLEQKALVSCIFFLEFAIMGLFSAKDGLLFYVFWEFSLLPLLYIMGVYGKDFRAGVKFFIYAFAGSILMLVALIYQAYLNYQLLNIFTFDLEIWKNNASAVNFTEQLLLFGAFFIAFAIKAPLFPLHTWAPKVYANSPVLVSVMLVVFKMAPFGFLLFCLPLFPDASVYFMPLIVALCIVSIVYNALIAYRAENIKELIAYSSISHLGVMILGIFSLNALGISGAVFYMFAHGIVTGALFLMVELLYQRYHTYDISFYHSLAKKAPLFSIFFMLILLASVSLPLTVSFVGEFLILLGIAKINLFYALLAGLVIILGAIYMFAVFRKIFFMQKQSFIEGFSLLFREIVALVCIVVMIFGLGLMPNILLKPIQKDVDNLIKTMNIRAVEQNTLDFLSKIGEANVK

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP019561	Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence	122239-122268	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP051433	Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence	5669-5698	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP024158	Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence	23984-24013	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	CP043759	Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence	68069-68098	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP024129	Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence	48532-48561	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP024133	Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence	22895-22924	6	0.8
NZ_CP040612_1	1.1|1464075|30|NZ_CP040612|CRT	1464075-1464104	30	NZ_CP024137	Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence	9887-9916	6	0.8
NZ_CP040612_1	1.3|1464207|30|NZ_CP040612|CRT	1464207-1464236	30	NZ_CP046714	Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence	7687-7716	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP019561	Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence	122239-122268	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP051433	Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence	5669-5698	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP024158	Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence	23984-24013	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	CP043759	Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence	68069-68098	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP024129	Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence	48532-48561	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP024133	Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence	22895-22924	6	0.8
NZ_CP040612_1	1.4|1464076|30|NZ_CP040612|PILER-CR	1464076-1464105	30	NZ_CP024137	Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence	9887-9916	6	0.8
NZ_CP040612_1	1.6|1464208|30|NZ_CP040612|PILER-CR	1464208-1464237	30	NZ_CP046714	Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence	7687-7716	6	0.8
NZ_CP040612_1	1.3|1464207|30|NZ_CP040612|CRT	1464207-1464236	30	KX119200	Helicobacter phage FrMEG235U, complete genome	2736-2765	7	0.767
NZ_CP040612_1	1.3|1464207|30|NZ_CP040612|CRT	1464207-1464236	30	KX119201	Helicobacter phage FrANT170U, complete genome	2736-2765	7	0.767
NZ_CP040612_1	1.6|1464208|30|NZ_CP040612|PILER-CR	1464208-1464237	30	KX119200	Helicobacter phage FrMEG235U, complete genome	2736-2765	7	0.767
NZ_CP040612_1	1.6|1464208|30|NZ_CP040612|PILER-CR	1464208-1464237	30	KX119201	Helicobacter phage FrANT170U, complete genome	2736-2765	7	0.767
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP019561	Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence	122239-122269	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP051433	Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence	5669-5699	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP024158	Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence	23984-24014	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	CP043759	Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence	68068-68098	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP024129	Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence	48532-48562	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP024133	Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence	22895-22925	7	0.774
NZ_CP040612_1	1.7|1464075|31|NZ_CP040612|CRISPRCasFinder	1464075-1464105	31	NZ_CP024137	Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence	9886-9916	7	0.774
NZ_CP040612_1	1.9|1464207|31|NZ_CP040612|CRISPRCasFinder	1464207-1464237	31	NZ_CP046714	Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence	7686-7716	7	0.774
NZ_CP040612_1	1.2|1464141|30|NZ_CP040612|CRT	1464141-1464170	30	JQ340088	Halocynthia phage JM-2012, complete genome	9348-9377	8	0.733
NZ_CP040612_1	1.5|1464142|30|NZ_CP040612|PILER-CR	1464142-1464171	30	JQ340088	Halocynthia phage JM-2012, complete genome	9348-9377	8	0.733

1. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP019561 (Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

2. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP051433 (Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

3. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP024158 (Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

4. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to CP043759 (Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

5. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP024129 (Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

6. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP024133 (Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

7. spacer 1.1|1464075|30|NZ_CP040612|CRT matches to NZ_CP024137 (Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

8. spacer 1.3|1464207|30|NZ_CP040612|CRT matches to NZ_CP046714 (Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence) position: , mismatch: 6, identity: 0.8

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tatttgaacctttaaaatcaagaaatccgt	Protospacer
********* .************** .  *

9. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP019561 (Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

10. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP051433 (Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

11. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP024158 (Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

12. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to CP043759 (Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

13. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP024129 (Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

14. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP024133 (Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

15. spacer 1.4|1464076|30|NZ_CP040612|PILER-CR matches to NZ_CP024137 (Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence) position: , mismatch: 6, identity: 0.8

taatggtgttgttaattggaatgcaaaagg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagg	Protospacer
**..  *********.*******.******

16. spacer 1.6|1464208|30|NZ_CP040612|PILER-CR matches to NZ_CP046714 (Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence) position: , mismatch: 6, identity: 0.8

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tatttgaacctttaaaatcaagaaatccgt	Protospacer
********* .************** .  *

17. spacer 1.3|1464207|30|NZ_CP040612|CRT matches to KX119200 (Helicobacter phage FrMEG235U, complete genome) position: , mismatch: 7, identity: 0.767

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tttttgaacgcttaaaagcaagattttgat	Protospacer
* *************** *****   *. *

18. spacer 1.3|1464207|30|NZ_CP040612|CRT matches to KX119201 (Helicobacter phage FrANT170U, complete genome) position: , mismatch: 7, identity: 0.767

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tttttgaacgcttaaaagcaagattttgat	Protospacer
* *************** *****   *. *

19. spacer 1.6|1464208|30|NZ_CP040612|PILER-CR matches to KX119200 (Helicobacter phage FrMEG235U, complete genome) position: , mismatch: 7, identity: 0.767

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tttttgaacgcttaaaagcaagattttgat	Protospacer
* *************** *****   *. *

20. spacer 1.6|1464208|30|NZ_CP040612|PILER-CR matches to KX119201 (Helicobacter phage FrANT170U, complete genome) position: , mismatch: 7, identity: 0.767

tatttgaacgcttaaaatcaagaaaatatt	CRISPR spacer
tttttgaacgcttaaaagcaagattttgat	Protospacer
* *************** *****   *. *

21. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP019561 (Escherichia coli strain KSC1031 plasmid pMRGN1031, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

22. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP051433 (Escherichia sp. SCLE84 plasmid pSCLE3, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

23. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP024158 (Escherichia coli strain 14EC047 plasmid p14EC047c, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

24. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to CP043759 (Escherichia coli strain CVM N55972 plasmid pN55972-1, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

25. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP024129 (Escherichia coli strain 14EC001 plasmid p14EC001b, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

26. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP024133 (Escherichia coli strain 14EC007 plasmid p14EC007b, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

27. spacer 1.7|1464075|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP024137 (Escherichia coli strain 14EC017 plasmid p14EC017c, complete sequence) position: , mismatch: 7, identity: 0.774

taatggtgttgttaattggaatgcaaaaggg	CRISPR spacer
tagctctgttgttaactggaatgtaaaagga	Protospacer
**..  *********.*******.******.

28. spacer 1.9|1464207|31|NZ_CP040612|CRISPRCasFinder matches to NZ_CP046714 (Nostoc sp. ATCC 53789 plasmid pNsp_k, complete sequence) position: , mismatch: 7, identity: 0.774

tatttgaacgcttaaaatcaagaaaatattg	CRISPR spacer
tatttgaacctttaaaatcaagaaatccgtt	Protospacer
********* .************** .  * 

29. spacer 1.2|1464141|30|NZ_CP040612|CRT matches to JQ340088 (Halocynthia phage JM-2012, complete genome) position: , mismatch: 8, identity: 0.733

actttagttttagactttggaacagtcgag	CRISPR spacer
actttagttttagacttttgatcttctgtt	Protospacer
****************** ** *  ..*  

30. spacer 1.5|1464142|30|NZ_CP040612|PILER-CR matches to JQ340088 (Halocynthia phage JM-2012, complete genome) position: , mismatch: 8, identity: 0.733

actttagttttagactttggaacagtcgag	CRISPR spacer
actttagttttagacttttgatcttctgtt	Protospacer
****************** ** *  ..*  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1372680 : 1381662	10	Bodo_saltans_virus(40.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP040612|1372680:1381662|DBSCAN-SWA
TTTATTTATTAATCCAATATTTGTCAATTAAATACTCATTTGGAGTTCCAAAAGAAAAATAGTTATCAAGTAAAACATAGTAAATTTTATTTTTACCAAGCATAAGATTAAAAACATTATCTATAAAAAATTCATCGTTAACTTTGACTTCTTTTTTAAACATTTCATTGATATAGGAAATTAAAGTTTGATTGTTTTTAAAATAAAAACTTCCTATCATAATTAAATGACTATTTTCAGCTCTATACTTCACACATATTTCCTTTACAAATCCTTTTTCATCACCATTTACCCAAGTAAAATAATTTGGATTATCGTAATTAAATTTGGAAGCTTTAGCAACAAAAATAATTGCATCAGATTCATCCTTTATTTTTTTAAAATCTGAATTTATATGCTTAGCAAGCAAATCACAAGGCAATATCAAAACATCTCCTTTCAAATCTGCACAAGATTCTTTATAAGAATACGCTGCGCCTATTTTATTTGGCTTAACATATCTAACTTCAGTTTTTATATTTTGCCAATATTTCTCATGATCTTGTGCTCCAACACAAATAATATTTGTATGGACATTCTCCAATTTTTCAATAATATTATTTATAATAGTTGATTGACCAAGCGGTAGAAATGGTTTAGGTTGAGAAAAATTTAAATTTAAAAATCTTTCACCACGACCAGCTGATAAAATTACAGTATTGTCTATATCAATTTGCTCGTTTATTAAGTTTGTACTTATTCTCAATTTTTCCTTGGCGTATTCGAAATCCTTTGGAGTGCCAAATTGATAAAACTTCTCTACAAAAGGATAGCAAAGTACTTTTTGAAGATAATTATTTGTTATTGATAAATAATATTCACCATTTAGCATATCAATAGCAGCAATCTGTTTTTCTATAGCTTCAAAAACTATTTTTAAAGATTTAAAATAATAAATTCCGCTAGAGTGAAATTCATTAAATTTATCTTTAGAGCAATATTTTTCTATAACTTTATATACGGTATTGCTTTTATCATATACTTTACATACCGCATAAACATTCTCAACTGGTTCTAGATGTGGATGATAACCCGTATAACAAGGAATAATACCTTGTGCTTCATTATTCTTTTTAACAAAATCTAAAAAATGTTCATAGTTCCATTTTTGACCAAAATCACAATAGCTAACAATTACAGGCTTGTCTAAAATTTCATCTAAAAAATCTCTTACACCAATTAAAGTTCCAGCTGGACCAAGCTTTAATCCATCATAGACTATGACATTAGCATTTAACTTTCTGCTTGTTATAAAATTAATAAATTTATCCTGCTCTTCTTTTCTAATAATAAAATAAAATTTATCTTTTATTTTATCAAAACAATTTACCACAAAATCTAAAATACAATTATTTTCATTTACTTTTATAAACGGTTTTAACTCTTTATAACCAGCTTCCTTAAAACGCTTGCCTATTCCAGTGGCTGGTATAATAATATTCATTATTTCTCCTTATCTTGCATATACCCATATCGGTATTTTTCTTCTGGCATATTAATCAAGTTTGTAATTTGTATTGCACTAATTTCAGATAAATTTAATTGTTTTTTTCTAGCAATATTTTCCATTGCCTCTCTAAATAACCACAACTCAAAACTTTCAACATCTATAGCATCATCGGGTGTAAAAATGTTATTATTTTTTTCAAAAAATTCATTTTTTAATGTTTGATGAAGTATAAATAAATCTTCTAGTATTTCTGAAAATATAATAACTCCATGATTTCTTAACATTACCATTCCTTTTTGCTCATAATAATACTTTTTAGATAATTCTTTACATAATTGTTCTCCAGGTAAAATAAAGTCTATGCATTTATAAGTAAATTTAAAATTTTTATCACAAAGATATGGTAAAATATAGACTGGATGATAATGAACTACATATTTATTTTGAATTATTCTATGCATTCCAATCTCCATTGAAGGCTTTGTTATATTGCCTATTTTATTACTAAAATAAGTTCCAATATTATTCTCATTTTCCAATATGCAAATTTTGTGTTCTTGTTTTAAATCTTGACCAGAGGCTTTTATAATCATATATTTATCATTTTTTATTGAAATATTACCTCCTTTAGAAGGAGTATCTAAAATATTTCCAAAAACCTTACATATATTATAATACTCTTTAATTAAACAATGCAATTCTTTATTTATTTCCATTTCACTTTACCCAACGATTATTTATAATTTTTGACATTATATCTTTAATAGTATCAATTAAATTATGATATTCACCTTCATAAATATTTTGCAAGTTAGCACTTTTTAAAATACCTGAAAGTTCTATTTTAAATTTCTTATTTCTTATCGTAATTAAAAAATTTGCATTATCTTTTTGTTTATACAAATAATGCAGATAATCTTCTTCTCGCTTTTGGATAGAATTAATAATTTTATCTAATTTATATCCACGTTCTTTTATATCTCTTTGTATTTTTTGATTGTCAGATTCATCTGAATCTATAAAAATTTTAATTTTTACAAAATCACCAATAACCTCTTGATATAAAGTATGCAAACCTTCAATAATTACAATATCCAAATCCTTTGTTTTTATCAGATCTGATGTCAAAAAATTACCAGAAACATGATCATATAGCGGAATACATAAATCATGAATATCTTGATATATACATTTAATATCTAACGCCAATTGAATAAGATTGTTCCCCTCTGGATTATAATGTGTTATTCTCTCCCATACAGTAGAATACCTATCAAATTTATGGTAACCATCAGCACCAATTACCATACAATCACAAACCGATTTAATAGCACTACCAAGTGTAGATTTTCCAGATCCACTTTTACCAGATATAGAAATTAATAATTTTGAACAATTATAAGGATAATACTTTATATCATAAATACCTAGATCATCAGCTATAGAATCTCCTATCATTACAACCTTATCTTTTGAGTCAATTTTAGCTAATTCAAAAGCTCTATCTATTAATTTTTTATGTGGCTTTTCCACTTCAAATTCTTCTGAGCAAATTAAAAAATCAAGCATTAAAGATAAATTTGCATAATTAAGTTTGTTAATTTGTTCAATAAAATAAAAATTAGTAATGGCTAAAATCTTTCTATTAATACTTTTAGCATAAACTAAAAAATCAAACATTGTCTTATCAACTTTAATATTATAGAGAAATTCTTTTATGTATAACTCAAACATATTTTTAGCCTGAATAAAATGTATATTTTTCTCTTCACACATTAATTTAAAGTATAATTCTTTTTTATGATGATTTACAGATAAATCTCGAGCTTTAATTTGCATTCTTGCATATTCATAATCTTCCATCGAAAAATTATATTTTTTTAAAACATTTTGCAAAGCTTTGTTATGTGCATAAGTATAGTTAAATAAAGTATTGTCAATATCCACCATAATAAGTTGATATTTATTAGCTAAATACTGAAAATTAAACATAAGAACCCCAAAGCTCCGGATTTTTTGTACATACTGAAAAACTATTTGGCAAAACTTGACAAATTTGTTGTATTAAGACTGTATAAGATAAATTATAAAGCTCCGGTGATACTATAATGGGCTCTATTTTTTTATCGATACTTTTATACAAATTGTTAATAAACTTAGCATATTCTTTTATATCGAAATCAGCAAATTGAGAATAATCAACCCATAAATACTTTGGCTCAGTTAATTCAATAATCTTGTAATTTAGTGTTTCTACATCAGAAACACGAATGATAAATTTCCCTTTTATTTTTTTTGAAATTCTTAAAATATCAGGAATCTGAGAATCTAAAAAATAATACTCATACCCCCCTGTCATCATTTTACCATGATTGTCAAAAATCTCAATAACAAGCTCTTCTAAATTTGATTCTTTAATATTGCAAATTATGGGTATATTTTTAAAGAATTCTAATTTTTCAGTAAATAACGGATATTTTATATTAGATTCGAGTAAATCATGATTTAAAACCAAACCTTGTTTATTACGCCTTAAATCAATCTCTACACCAAAATTTCTAACTTTCTTAGAAATATTATTTTGACGATGTAAAAAAACCATCTATATTACCTTTATACATAAAATTATAATAATCCTCAGGCACGCCAATATCTATAAAATAATCATCAAAAATATGAGCTTTAGCTTTTAGTTTTTTATAATTTTCTTGCAAAAATTCTTCAAAAGAAAATTTTTCCTGCAAAGCAAAATCTTTAAAAATATCTTTATCTAAAAGATAAATTCCACCATTGATTAAACCTTGCTTTTTGAATACCTTTTCCTCAAAAGAAATTACAAGACCTAGCCCATCAACATTTACCGTGCCATATCTATCAAAATCATTCATTTGTTTTAAAGCAAGGCAAATTTTACCTCCATTTAGCTTTAATTTGCTTAAATCTATGCCAAAAAAAGTATCGCCATTTAAAACATAAGCCTCGTTTTTTATAATTTTCAAAGCCTCTTTTATAGCTCCACCCGTTCCTAGAGGCTCTTTTTCTATACTGTATTTTATTTTTATGCCTAAAAACTCATCTTTAAAATACTCTTTTATCACTTCATATTTGTATGATACCGCTAAGATAACTTCTTTTATGCCTTGCTTTTTAAGATACTCAAAAATAAATTCTAAAAAAGGCTTATCATTTATCGGTGCCATAGGCTTTGGAATGTCTTTTATAACACTTTTAAGCCTTGTTCCTAAGCCGCCACAAAGTATTATTGCTTGCAAGAAAAACCTTTGCCAAAAAGCTCTTCTTCAACGATAGCACAAATAATATGTCCTATTAAAATATGTGCTTCTTGAATTCTTGGTGTGCAAGTTGAAGGTACTTTTATACAATAATCACAAAGCTCATTCATATCCCCGCCATTAGCTCCGCTTAAGCCTATGCTTATGATTTCTTTTTGCTTGCAAAGCTCTAAAGCCTTTAAAATATTTTTACTATTTCCACTTGTAGAAATTCCTATAAAAACATCTCCTTTAACACCCTGTGCTTGCACTTGTCTTGCAAATAAATTTTCATAACCATAGTCATTGCCAATAGCTGTTAATATGCTAGTATCTGTAGTAAGTGCAATACTTGCGATACCGGGTCTATCAAAATAAAACCTACTTACAAATTCCCCTGCGATATGCTGTGCATCTGCAGCACTACCACCATTTCCTGCAAGTAAAGTTTTGTTACCATTTTTATAAGCTTTTATGACTTCTAATGAAGCATTTTTAATAAGAGTTATCAAATTCTCATCTTTTAAAATTTGCTCTTTTACTAAAATTGATTCTTGAAAATGTTCTTTTATATAAGAATTTAAATTCTCCATGATTTAACCCCCTCTTTTGTAAATGAAAAATCTTGCACATAACCTTGCTCTTTGCTTAAAGCTTTGATTAAGTTGTATTTTTTTGTAGGATCCACAAAGAAAAACATAAATCCACCTGCTCCTGCTCCACTAGTTTTGCCACTATAAGCTCCATTATCTATAGCTAGTTTATAAATTCTTTCAAGCTCATCATTACTAACGATTTCTGAAATGATTTTTTTTGACTGCCAAGACTTGCCTAAAATTTTCGCCAAAGTATCAAAATCCGCCTTAAATAAAGCTTCTTTCATCTTTATAGCATCTTGTTTTATAGCGTGCATAGCTTCAAGGGATTTTTCATCTCCGAGCTTTCCTTTTTTATGCTCTTCTATATCTTTTGCTTCTCTTGTGATATTTGTAAAATAAAGCACAATTCTAGCTTCAAGCTCACTAGCTATCCAGTTTTTAATGCGCAAAGGATTAACAATGACTCTTTTATTATTATAAAATTCCATAAAATTAAAGCCACCAAAAGTTGCGGCGTATTGATCTTGTGCTCCACCTACTATACCTAAATCTTCTCTTTCTATCTCATAAGCAAGTTTAGCGATTTCATATTCCCCTAAAGGTAGATTAAGCCATTCTGCAAAGGCTTTTATAACCCCTACAACTAAGGTTGAGCTTCCGCCCAAACCACTACCACTTGGTACATCCGAATAAGTGTGCAAAGAAAAACTCAAAGGTTTTTTTGTAAAATCTTTTACAATGCGATTATAAATGCTTTTAAAAATATCTAATTTTCCATCATTTTCTAAGAATTCTTTGCTTTCATACTCACAGTAAGAATTTGTATCAGGAGAATCAAAAATGATTTTTCCATCTTCTCTTTCGATCAAAGTACAATGTATGTATAAAGATATAGTCGCATTTAAAACATAACCTGTGTATTTATCACAATATAAATTTATATCAGTCCCCCCACCTGCTAAACCAAGGCGGAGAGGAGTTTGCGTGCGTATAGTTTTCATCTATTTAAAGGAATCCTTCCTTTTTTTATCTCGTCTCTCCAATGATTTAACAAATCCTCAAACATTTTTCTAGCTGGAATTTCTGGCTTCCAGTTGATATAACGTTTGATTTTAGTATTGTCAAACATTTGATAATCCGCATCAATAGGACGCAATCTTTCTTCATCTTGCTCTACTTTAATATCTTTTCTTGTAGAAAAACCTAAAAGTATATCAATAACCTCAGGGAGTTTAAAAACTTCTTCTCCTGCTATATTAAAAGCTTCCCCACAAGGAACTTTTCCTTTTTCACTTTCAAGAGAAAGTAGATAATAAGCCCTTATAGCATCACGACAATCTTGAAAGGTTCTTACACTTGAAAGATTTCCAACCTTGATAACAGGCTCTTGATAACCCGCTTCAATCAAAGCAATTTGCTTTGCAACCGTGCTTTCAAAAAACACATCGCTTCTTCTTGGACCACTATGTGTTCCCATTCTTGTAACAAAGCTGCGGATGTTATAAGCTTCGCCATAAAATCTTCCTAAGTAATCAGTGCCGATTTTGCTTATACTATAAGGACTTGCACCGTGAAAAGCTGTTTCTTCATTAAGTTTAACACCTGCTTTTGCTTTACCATAAACTTCGCTTGAAGAGCATACATGCACTACAGGGTCATATCCATCTTTTGCCTTTAAAATTCTAATGTTTTCTAGGATATTTGCCGTGCCTATTATGTTGGTTTGTAAAGTTTCAATCGGTATATCAAAAGAAGTTTTTGGGTAAGACTGAGCTGCTAGGTGAAAAATCACATCAGGCCTTTGACTCTCGAAAAGTTTTTGAAGACTAGAGCAATCATTTAAATCTGCATAAAAAATGCTGATTCTATCTTTTTTATTAATCCTATCGCTTAAATGATAGATATTATCCATAGGTTCTTGCCAACGCATCATACCTATAACATCATAGTCTGTGTTTTCTAGCAAGAAATCTGCCATTTGTGAGCCAACTTGCCCTGTAAAACCTGTAATTAATGCTGTTTTTTTCATGATTTATCCTATTGTCTTATATTTTGCTCTTTTAAATACCATTCATACATCATTTTAATGCCGTCTTCAAGCTTGATTTTTGCCTTCCAGCCTAAATTTTGCAATCTTGAACTATCTAACATTCTATCCATTGTAGAATCTGGTTTTGAATTGTTAAACACAATTTCACCCTTAAATCCAACAATATTTTTAATCAAACAAGCAAGTTCTTTTATGCTTAAAAATTCCCCACTTCCTACATTAAGATGCGGTTCATTAGATGAAACAATATCTTTAAAATCTATATTTTTCATCACATAAATAGAAGCATCGACTAAATCTTTTGCATGAATAAATTCCCTAATTACACTACCACTACCCCAAATTTCTACGCTATCTTTACTTACACCAAATTTTTGTAAATATTCCATTGCTTGCTCTAAGAAATTCATTTGCAAATCCTTTAAAACCTCATCAATTTTATTTTCATCTAAAAGCTTTGCTAAATGAAATTTGCGAAGCAAAGCCGGTAAAACTTTTGCTTTTTGTAAATCAAACTCGGTTGTTTCTCCATACAAATTTGCAAGATACAAAGTGATAAAATTTGTTCCATATTGCAAATTATAACTTTCGCACATTTTTGTTCCTATAATTTTTGGTAAACCATATGCAACGGCTTTTAAATCTAGCTTTCCATCTAATAAATTCTCTTCTTTAATGGGATTTATAGCTTTTTGAGGGTAAGCCCAAGCAGAACCATAAAAAATTAGCTTTTTAACATTATTTTGATAAGATGAATGAATAATATTTGCTTGAAGTACGCTATTTTCATAAATTACATCGGCTGGAGTAAAAAGCCCTAAGGTATCAAGCTTGGCAGCACATAAAAAAACATATTCTGGTTTTTCTTTTGCGAAAAAATCAGTCACAGCTTTTTGATCTACTAAATCTAATTCTTTTCTTGTTTTTACGATAATATTATTAAAACCCTCATCTATAAGTGTATTATAAAGAGTTTTTCCCAAAGTGCCGCCATGCCCTGCTATATAAATTTTAGAATCTTTTTGCATCATTTATCCTTACTCATCGCTAAAATATCACGCTCTGAAAGGATAGGAGAATTTGTTGGCCAATCTATGCCTATTCTTTCATCATTCCATGCATAAGTAAATTGATCATGTGCATCCATATATTCTCCTAAATAAGCACATTTATAGTAATAAACTGCACTTTCACTGCTAACATAATGAGCATTTCCAAAACCTGCTGGAACTAAAATGATTTGCTGATTATCTTGATTTATGATGAATCTTTCATGCTTCAAATAAGTTGGTGAATCTTTTCTGCAATCTACCACCACCTGATGAATTTCCCCATAAATACAAGTTGCAAGCTTATAAGTTTTTACATCGCCATGGATACCGCGGATAACATTGTGTTTAGAATGTATGAATTTATCGTGTATAAATTTTAATCCATTTGGCAAGAGTTTATCTATAGCTTCACTTGTAAAAGCTGTCCAAATTTCACCTCTTAAATCTCTAAATTTATTAGGAGTTATAATATATACACCTTTTAGAATTTTTGATTCTTGTATATCAAATTCTATTGCCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP040612|1372680:1381662|1374885_1376160_-|WP_002872118.1|DBSCAN-SWA
MFNFQYLANKYQLIMVDIDNTLFNYTYAHNKALQNVLKKYNFSMEDYEYARMQIKARDLSVNHHKKELYFKLMCEEKNIHFIQAKNMFELYIKEFLYNIKVDKTMFDFLVYAKSINRKILAITNFYFIEQINKLNYANLSLMLDFLICSEEFEVEKPHKKLIDRAFELAKIDSKDKVVMIGDSIADDLGIYDIKYYPYNCSKLLISISGKSGSGKSTLGSAIKSVCDCMVIGADGYHKFDRYSTVWERITHYNPEGNNLIQLALDIKCIYQDIHDLCIPLYDHVSGNFLTSDLIKTKDLDIVIIEGLHTLYQEVIGDFVKIKIFIDSDESDNQKIQRDIKERGYKLDKIINSIQKREEDYLHYLYKQKDNANFLITIRNKKFKIELSGILKSANLQNIYEGEYHNLIDTIKDIMSKIINNRWVK
>NZ_CP040612|1372680:1381662|1378020_1379040_-|WP_002872115.1|DBSCAN-SWA
MKTIRTQTPLRLGLAGGGTDINLYCDKYTGYVLNATISLYIHCTLIEREDGKIIFDSPDTNSYCEYESKEFLENDGKLDIFKSIYNRIVKDFTKKPLSFSLHTYSDVPSGSGLGGSSTLVVGVIKAFAEWLNLPLGEYEIAKLAYEIEREDLGIVGGAQDQYAATFGGFNFMEFYNNKRVIVNPLRIKNWIASELEARIVLYFTNITREAKDIEEHKKGKLGDEKSLEAMHAIKQDAIKMKEALFKADFDTLAKILGKSWQSKKIISEIVSNDELERIYKLAIDNGAYSGKTSGAGAGGFMFFFVDPTKKYNLIKALSKEQGYVQDFSFTKEGVKSWRI
>NZ_CP040612|1372680:1381662|1376152_1376770_-|WP_052824105.1|DBSCAN-SWA
MVFLHRQNNISKKVRNFGVEIDLRRNKQGLVLNHDLLESNIKYPLFTEKLEFFKNIPIICNIKESNLEELVIEIFDNHGKMMTGGYEYYFLDSQIPDILRISKKIKGKFIIRVSDVETLNYKIIELTEPKYLWVDYSQFADFDIKEYAKFINNLYKSIDKKIEPIIVSPELYNLSYTVLIQQICQVLPNSFSVCTKNPELWGSYV
>NZ_CP040612|1372680:1381662|1381116_1381662_-|WP_002872112.1|DBSCAN-SWA
MAIEFDIQESKILKGVYIITPNKFRDLRGEIWTAFTSEAIDKLLPNGLKFIHDKFIHSKHNVIRGIHGDVKTYKLATCIYGEIHQVVVDCRKDSPTYLKHERFIINQDNQQIILVPAGFGNAHYVSSESAVYYYKCAYLGEYMDAHDQFTYAWNDERIGIDWPTNSPILSERDILAMSKDK
>NZ_CP040612|1372680:1381662|1376744_1377440_-|WP_002872116.1|DBSCAN-SWA
MQAIILCGGLGTRLKSVIKDIPKPMAPINDKPFLEFIFEYLKKQGIKEVILAVSYKYEVIKEYFKDEFLGIKIKYSIEKEPLGTGGAIKEALKIIKNEAYVLNGDTFFGIDLSKLKLNGGKICLALKQMNDFDRYGTVNVDGLGLVISFEEKVFKKQGLINGGIYLLDKDIFKDFALQEKFSFEEFLQENYKKLKAKAHIFDDYFIDIGVPEDYYNFMYKGNIDGFFTSSK
>NZ_CP040612|1372680:1381662|1379036_1380068_-|WP_002896840.1|DBSCAN-SWA
MKKTALITGFTGQVGSQMADFLLENTDYDVIGMMRWQEPMDNIYHLSDRINKKDRISIFYADLNDCSSLQKLFESQRPDVIFHLAAQSYPKTSFDIPIETLQTNIIGTANILENIRILKAKDGYDPVVHVCSSSEVYGKAKAGVKLNEETAFHGASPYSISKIGTDYLGRFYGEAYNIRSFVTRMGTHSGPRRSDVFFESTVAKQIALIEAGYQEPVIKVGNLSSVRTFQDCRDAIRAYYLLSLESEKGKVPCGEAFNIAGEEVFKLPEVIDILLGFSTRKDIKVEQDEERLRPIDADYQMFDNTKIKRYINWKPEIPARKMFEDLLNHWRDEIKKGRIPLNR
>NZ_CP040612|1372680:1381662|1372680_1374162_-|WP_002872120.1|DBSCAN-SWA
MNIIIPATGIGKRFKEAGYKELKPFIKVNENNCILDFVVNCFDKIKDKFYFIIRKEEQDKFINFITSRKLNANVIVYDGLKLGPAGTLIGVRDFLDEILDKPVIVSYCDFGQKWNYEHFLDFVKKNNEAQGIIPCYTGYHPHLEPVENVYAVCKVYDKSNTVYKVIEKYCSKDKFNEFHSSGIYYFKSLKIVFEAIEKQIAAIDMLNGEYYLSITNNYLQKVLCYPFVEKFYQFGTPKDFEYAKEKLRISTNLINEQIDIDNTVILSAGRGERFLNLNFSQPKPFLPLGQSTIINNIIEKLENVHTNIICVGAQDHEKYWQNIKTEVRYVKPNKIGAAYSYKESCADLKGDVLILPCDLLAKHINSDFKKIKDESDAIIFVAKASKFNYDNPNYFTWVNGDEKGFVKEICVKYRAENSHLIMIGSFYFKNNQTLISYINEMFKKEVKVNDEFFIDNVFNLMLGKNKIYYVLLDNYFSFGTPNEYLIDKYWINK
>NZ_CP040612|1372680:1381662|1380076_1381117_-|WP_002872113.1|DBSCAN-SWA
MQKDSKIYIAGHGGTLGKTLYNTLIDEGFNNIIVKTRKELDLVDQKAVTDFFAKEKPEYVFLCAAKLDTLGLFTPADVIYENSVLQANIIHSSYQNNVKKLIFYGSAWAYPQKAINPIKEENLLDGKLDLKAVAYGLPKIIGTKMCESYNLQYGTNFITLYLANLYGETTEFDLQKAKVLPALLRKFHLAKLLDENKIDEVLKDLQMNFLEQAMEYLQKFGVSKDSVEIWGSGSVIREFIHAKDLVDASIYVMKNIDFKDIVSSNEPHLNVGSGEFLSIKELACLIKNIVGFKGEIVFNNSKPDSTMDRMLDSSRLQNLGWKAKIKLEDGIKMMYEWYLKEQNIRQ
>NZ_CP040612|1372680:1381662|1377427_1378033_-|WP_002896838.1|DBSCAN-SWA
MENLNSYIKEHFQESILVKEQILKDENLITLIKNASLEVIKAYKNGNKTLLAGNGGSAADAQHIAGEFVSRFYFDRPGIASIALTTDTSILTAIGNDYGYENLFARQVQAQGVKGDVFIGISTSGNSKNILKALELCKQKEIISIGLSGANGGDMNELCDYCIKVPSTCTPRIQEAHILIGHIICAIVEEELFGKGFSCKQ
>NZ_CP040612|1372680:1381662|1374161_1374884_-|WP_002872119.1|DBSCAN-SWA
MEINKELHCLIKEYYNICKVFGNILDTPSKGGNISIKNDKYMIIKASGQDLKQEHKICILENENNIGTYFSNKIGNITKPSMEIGMHRIIQNKYVVHYHPVYILPYLCDKNFKFTYKCIDFILPGEQLCKELSKKYYYEQKGMVMLRNHGVIIFSEILEDLFILHQTLKNEFFEKNNNIFTPDDAIDVESFELWLFREAMENIARKKQLNLSEISAIQITNLINMPEEKYRYGYMQDKEK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002872120.1|1372680_1374162_-	NTP transferase domain-containing protein	A0A2H4UUJ1	Bodo_saltans_virus	3.4e-47	28.3
WP_002872119.1|1374161_1374884_-	class II aldolase/adducin family protein	A0A2H4UUW4	Bodo_saltans_virus	1.5e-11	30.4
WP_002872118.1|1374885_1376160_-	HAD hydrolase-like protein	A0A2H4UUR3	Bodo_saltans_virus	7.6e-19	25.6
WP_052824105.1|1376152_1376770_-	hypothetical protein	A0A2H4UUJ1	Bodo_saltans_virus	2.2e-08	26.6
WP_002872116.1|1376744_1377440_-	NTP transferase domain-containing protein	A0A0G2Y8M0	Acanthamoeba_polyphaga_mimivirus	8.1e-07	27.6
WP_002896838.1|1377427_1378033_-	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.3e-16	35.0
WP_002872115.1|1378020_1379040_-	D-glycero-D-manno-heptose 7-phosphate kinase	A0A222YW25	Synechococcus_phage	3.0e-58	40.2
WP_002896840.1|1379036_1380068_-	GDP-mannose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	3.2e-145	72.7
WP_002872113.1|1380076_1381117_-	NAD-dependent epimerase/dehydratase family protein	M1HKX0	Paramecium_bursaria_Chlorella_virus	7.5e-65	40.2
WP_002872112.1|1381116_1381662_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	A0A1D7XFA9	Escherichia_phage	4.8e-15	29.3