CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP038229	Staphylococcus aureus strain MJ163 chromosome, complete genome	3 crisprs	cas3,DEDDh,DinG,csa3,WYL	1	2	7	0
NZ_CP038230	Staphylococcus aureus strain MJ163 plasmid unnamed1, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038229_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038229_1

246562-246652

Orphan

Consensus_repeat	Method
GGGCCCACACCCCAACTTGCATTGCCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038229_1

>merge|NZ_CP038229|1|246562-246652|CRISPRCasFinder
GGGCCCACACCCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGTCTGTAGAA

>NZ_CP038229|1|1|246562-246652|CRISPRCasFinder
GGGCCCACACCCCAACTTGCATTGCCTGTAGAA	TTTCTTTTCGAAATTCTCTTTGTTG
GGGCCCACACCCCAACTTGCATTGTCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038229.1\|WP_045178282.1\|241237_242281_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
NZ_CP038229.1\|WP_000240920.1\|250274_251963_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_CP038229.1\|WP_000950281.1\|254779_256534_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_CP038229.1\|WP_000638475.1\|242808_243525_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|184017
NZ_CP038229.1\|WP_001012736.1\|235657_237754_+\|transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP038229.1\|WP_000230358.1\|241067_241214_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_045178271.1\|257389_257833_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_CP038229.1\|WP_000610203.1\|249227_250253_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176199
NZ_CP038229.1\|WP_045178278.1\|251995_253717_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|376098
NZ_CP038229.1\|WP_000872486.1\|248518_249235_+\|D-ribitol-5-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|184017
NZ_CP038229.1\|WP_053520940.1\|240010_241066_+\|zinc-binding-dehydrogenase	unknown	unknown	gnl\|CDD\|176219
NZ_CP038229.1\|WP_045178276.1\|253860_254535_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_CP038229.1\|WP_045178274.1\|256536_257277_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_CP038229.1\|WP_045178286.1\|237738_238206_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
NZ_CP038229.1\|WP_000167978.1\|244564_246259_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_CP038229.1\|WP_000610183.1\|243517_244543_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176199
NZ_CP038229.1\|WP_000607067.1\|257825_258527_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_CP038229.1\|WP_000598262.1\|247073_248243_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_CP038229.1\|WP_000120119.1\|238733_239993_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
NZ_CP038229.1\|WP_000815795.1\|238228_238507_+\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908

Protein	Function_ID	Function_description	E-value
NZ_CP038229.1\|WP_045178282.1\|241237_242281_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	1.70725e-178
NZ_CP038229.1\|WP_000240920.1\|250274_251963_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NZ_CP038229.1\|WP_000950281.1\|254779_256534_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_CP038229.1\|WP_000638475.1\|242808_243525_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	3.70751e-127
NZ_CP038229.1\|WP_001012736.1\|235657_237754_+\|transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	2.82259e-85
NZ_CP038229.1\|WP_053520940.1\|240010_241066_+\|zinc-binding-dehydrogenase	gnl\|CDD\|176219	cd08258, Zn_ADH4, Alcohol dehydrogenases of the MDR family. This group shares the zinc coordination sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of an beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.45801e-145
NZ_CP038229.1\|WP_045178271.1\|257389_257833_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	1.03108e-63
NZ_CP038229.1\|WP_000610203.1\|249227_250253_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	0
NZ_CP038229.1\|WP_045178278.1\|251995_253717_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	2.90068e-35
NZ_CP038229.1\|WP_000610183.1\|243517_244543_+\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	1.32605e-178
NZ_CP038229.1\|WP_045178276.1\|253860_254535_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	4.88494e-152
NZ_CP038229.1\|WP_045178274.1\|256536_257277_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	8.32363e-152
NZ_CP038229.1\|WP_045178286.1\|237738_238206_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.03998e-36
NZ_CP038229.1\|WP_000167978.1\|244564_246259_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	2.13273e-114
NZ_CP038229.1\|WP_000872486.1\|248518_249235_+\|D-ribitol-5-phosphate-cytidylyltransferase	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	2.28851e-105
NZ_CP038229.1\|WP_000607067.1\|257825_258527_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_CP038229.1\|WP_000598262.1\|247073_248243_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	1.25735e-161
NZ_CP038229.1\|WP_000120119.1\|238733_239993_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	0
NZ_CP038229.1\|WP_000815795.1\|238228_238507_+\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.43648e-34

>NZ_CP038229.1|WP_000167978.1|244564_246259_+|CDP-glycerol-glycerophosphotransferase-family-protein
MTKTKQAIHIDNIYWERVQLYIEGHSEGVDLTSGQFVLRNLTETKTLEANEMKIDGNTFICRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAYAALNEEQIEEYNELTTQNGKVNYLLAYDAKVFRKGGVSQHTVYTITPEIASDVNEFVFDIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFTSDSRPNLSGNFKYVYDELLRQKVDFDYDIKTVFKANITDRRKWRDKFRLPYLLGKADYIFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKHNAVVLFKMHPFVKNRLNISREHRQYFIDVSDHREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR
>NZ_CP038229.1|WP_000610183.1|243517_244543_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENYLASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKSIPLKTSFGIWGDGNLGYITAILLRKLYPEAKIYVFGKTDYKLSHFSFVDDIFTVNQIPDDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGKTVLKWTI
>NZ_CP038229.1|WP_000638475.1|242808_243525_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
>NZ_CP038229.1|WP_045178282.1|241237_242281_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGVEDLRYEDNEKPVIESENDVIVKVRATGICGSDTSRYKKMGPYIKGMPFGHEFSGVVDAIGSDVTHVNVGDKVTGCPAIPCYQCEYCLKGEYARCEKLFVIGSYEPGSFAEYVKLPAQNVLKVPENVDYIEAAMVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIATSLGAHQTINSKEENLEKFIENHYANQIDLAIESSGAKVTIGQILTLPKKGGEVVLLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPIISHFLPLEKGPETFDKLVNKKERFDKVMFTIY
>NZ_CP038229.1|WP_000230358.1|241067_241214_+|hypothetical-protein
MVESMLTFMLGPLRQITDFYMEHLLVSNSIVIAGYFATGIFKKKKVVN
>NZ_CP038229.1|WP_053520940.1|240010_241066_+|zinc-binding-dehydrogenase
MKALVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYEGHYKVNFPVTLGHEFSGEIVEVAADVKDFKVGDRVTSETTFYVCNECEYCKSKDYNLCNHRKGIGTQVDGAFTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLVAQVLKSKGATVVVTGLDNDKVRLDKAEALHMDYVVNLQQTDLKTYINGITDGYGADVVVECSGAVPAARQGLDILRKKGFYSQIGIFKDAEIPFDMEKVIQKEITVVGSRSQKPADWEPSLQLMADGLVNAEALVTKIYDISKWDEAYQHLKSGEGIKALLKPLDLDENEGEN
>NZ_CP038229.1|WP_000120119.1|238733_239993_+|PTS-galactitol-transporter-subunit-IIC
MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLTIGVAFVGIFLVIDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFIIPLGIIVNVVLLVTKVTKTMNVDIWNFWHYTFTAAMVYSVSGSIWQALLAAVIFQIICLKVADWTAPMMSEFFDLPGVSIATGSTISYAPGIYLVKLLQKVPGLNKLDADPETIQKRFGAFGESIFVGLILGLGIGVLAGYKPGDIINLGMSMAAVMVLMPRMVKILMEGLMPVSESARTWLNKRFGEREIYIGLDAAVALGHPAVISTALILVPITVLLAVILPGNQVLPFGDLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATDVAPIFTDMAKGTNVQMPKGSSEISSIDQGGNIVNYLIFKLFSLFN
>NZ_CP038229.1|WP_000815795.1|238228_238507_+|PTS-sugar-transporter-subunit-IIB
MKQVLVACGAGIATSTVVNNAIEEMAKEHNIKVDIKQIKITEVGPYEDTADLLVTTAMTKKEYKFPVINARNFLTGIGIEETKQQILTELQK
>NZ_CP038229.1|WP_045178286.1|237738_238206_+|PTS-sugar-transporter-subunit-IIA
MGQQLVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDAVIDREKEFATGLPTHLCSVAIPHTDVEHINHRTIGVAVLEKEVPFIEMGTLDQQTEVKIVFMLAMNKVDDQLKLLQQLIQIFQSEEKLEQILRTKDETILATLINDYLEYN
>NZ_CP038229.1|WP_001012736.1|235657_237754_+|transcription-antiterminator
MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLWLEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLFSKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLEDHGLSLKYSRKHGYEIVGDEFEVRRFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLPYVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLLSTSVQWTDLQESDNISNLTMAIAQMIHHFEQITFINIEDKEKLSQQLLLHLTPAFYRIKYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRRQDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVFSPMFVLTHKKLFITKVALSENEQRKLRKDVMKYINKESADIDKEINKLMALIERTTTVNDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLADLIPARHVKRMHHVENIDEAIAKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSEKHVHKTAMSMLILQEPIYMSDGTAIHIIVPIAAVDKVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEILKNYSNKEARGNGWDSN
>NZ_CP038229.1|WP_000598262.1|247073_248243_+|CDP-glycerol-glycerophosphotransferase-family-protein
MIKTTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNPKALYEYLTEHSDAQLIWGVKKGYEHIFQQHNVPYVTKFSMKWFLAMPRAKAWMINTRTPDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFKKESQRWDYLVSPNPYSTSIFQHAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMYAPTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDVSDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKELPGPIVENQTALIDALKQIDETTNEYIEARTVFYQKFCSLEDGHASQRICQTIFK
>NZ_CP038229.1|WP_000872486.1|248518_249235_+|D-ribitol-5-phosphate-cytidylyltransferase
MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAIIRGGIADD
>NZ_CP038229.1|WP_000610203.1|249227_250253_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRYYTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTEKDDVIAENYLKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKSISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIPEGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTLIGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEFEIATINDLTEAFEADLSTSWGKTVLKWIM
>NZ_CP038229.1|WP_000240920.1|250274_251963_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NZ_CP038229.1|WP_045178278.1|251995_253717_+|glycosyltransferase-family-2-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQSQYYRFDIVDGKLNIQFNDGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSTLIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_CP038229.1|WP_045178276.1|253860_254535_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADIVTDYPKAADIFRSVGIDFCCGGHVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLDHMQKEDNVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_CP038229.1|WP_000950281.1|254779_256534_+|sensor-histidine-kinase
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_CP038229.1|WP_045178274.1|256536_257277_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRANKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_CP038229.1|WP_045178271.1|257389_257833_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVKKKIKIEEAQAHD
>NZ_CP038229.1|WP_000607067.1|257825_258527_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF

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Crispr_ID: NZ_CP038229_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038229_2

1916091-1916173

Orphan

Consensus_repeat	Method
AATTTCTACAGACATTGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038229_2

>merge|NZ_CP038229|2|1916091-1916173|CRISPRCasFinder
AATTTCTACAGACATTGCAAGTTGGGGGGGCCACAACAAAATGAAATTGGATCCTCAATTTCTACAGACATTGCAAATTGGGG

>NZ_CP038229|2|2|1916091-1916173|CRISPRCasFinder
AATTTCTACAGACATTGCAAGTTGGGG	GGGCCACAACAAAATGAAATTGGATCCTC
AATTTCTACAGACATTGCAAATTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038229.1\|WP_000379980.1\|1917761_1918889_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl\|CDD\|272993
NZ_CP038229.1\|WP_000375864.1\|1909748_1910213_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NZ_CP038229.1\|WP_000290301.1\|1908032_1908377_-\|YlbF/YmcA-family-competence-regulator	unknown	unknown	gnl\|CDD\|237467
NZ_CP038229.1\|WP_000116229.1\|1913772_1915158_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NZ_CP038229.1\|WP_000110011.1\|1932921_1933368_-\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_CP038229.1\|WP_169449292.1\|1921469_1922531_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_CP038229.1\|WP_000181394.1\|1917286_1917757_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|223297
NZ_CP038229.1\|WP_045176849.1\|1908445_1909570_-\|DUF445-domain-containing-protein	unknown	unknown	gnl\|CDD\|226834
NZ_CP038229.1\|WP_000901023.1\|1915353_1915749_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_000238226.1\|1905953_1907150_-\|exonuclease-SbcCD-subunit-D	unknown	unknown	gnl\|CDD\|223497
NZ_CP038229.1\|WP_000649907.1\|1919754_1921212_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223836
NZ_CP038229.1\|WP_000669376.1\|1912488_1913310_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP038229.1\|WP_001791795.1\|1907440_1907539_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_001808146.1\|1923023_1924343_-\|ISL3-like-element-IS1181-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_CP038229.1\|WP_001251224.1\|1916528_1917128_-\|glucosamine-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|223440
NZ_CP038229.1\|WP_000590809.1\|1919039_1919762_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP038229.1\|WP_001045133.1\|1910568_1911192_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NZ_CP038229.1\|WP_000031108.1\|1916351_1916504_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_045176847.1\|1911213_1912326_-\|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NZ_CP038229.1\|WP_045176936.1\|1933464_1934415_-\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632

Protein	Function_ID	Function_description	E-value
NZ_CP038229.1\|WP_000649907.1\|1919754_1921212_-\|ABC-transporter-permease-subunit	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.14709e-98
NZ_CP038229.1\|WP_000375864.1\|1909748_1910213_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	5.18868e-15
NZ_CP038229.1\|WP_000290301.1\|1908032_1908377_-\|YlbF/YmcA-family-competence-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	1.19759e-37
NZ_CP038229.1\|WP_001808146.1\|1923023_1924343_-\|ISL3-like-element-IS1181-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.72663e-114
NZ_CP038229.1\|WP_000110011.1\|1932921_1933368_-\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
NZ_CP038229.1\|WP_169449292.1\|1921469_1922531_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.3211e-121
NZ_CP038229.1\|WP_000379980.1\|1917761_1918889_-\|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	6.7316e-180
NZ_CP038229.1\|WP_045176849.1\|1908445_1909570_-\|DUF445-domain-containing-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	3.73472e-165
NZ_CP038229.1\|WP_000181394.1\|1917286_1917757_-\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
NZ_CP038229.1\|WP_000238226.1\|1905953_1907150_-\|exonuclease-SbcCD-subunit-D	gnl\|CDD\|223497	COG0420, SbcD, DNA repair exonuclease [DNA replication, recombination, and repair].	8.87443e-64
NZ_CP038229.1\|WP_000669376.1\|1912488_1913310_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.35529e-78
NZ_CP038229.1\|WP_001251224.1\|1916528_1917128_-\|glucosamine-6-phosphate-isomerase	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	1.49007e-10
NZ_CP038229.1\|WP_000590809.1\|1919039_1919762_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.70748e-153
NZ_CP038229.1\|WP_001045133.1\|1910568_1911192_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11819e-78
NZ_CP038229.1\|WP_000116229.1\|1913772_1915158_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NZ_CP038229.1\|WP_045176847.1\|1911213_1912326_-\|GAF-domain-containing-sensor-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.05548e-57
NZ_CP038229.1\|WP_045176936.1\|1933464_1934415_-\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	1.5208e-134

>NZ_CP038229.1|WP_000901023.1|1915353_1915749_-|hypothetical-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>NZ_CP038229.1|WP_000116229.1|1913772_1915158_-|class-II-fumarate-hydratase
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHQIDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCEIMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAHYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>NZ_CP038229.1|WP_000669376.1|1912488_1913310_+|RluA-family-pseudouridine-synthase
MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPARLMDKVHTGDDVFVPTIDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKESNTLMNHVIYTIDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKANVKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKEAVCQLEIKLDTGRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD
>NZ_CP038229.1|WP_045176847.1|1911213_1912326_-|GAF-domain-containing-sensor-histidine-kinase
MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFISSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGMSSESIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK
>NZ_CP038229.1|WP_001045133.1|1910568_1911192_-|response-regulator-transcription-factor
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI
>NZ_CP038229.1|WP_000375864.1|1909748_1910213_-|helix-turn-helix-transcriptional-regulator
MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEKERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNNIETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI
>NZ_CP038229.1|WP_045176849.1|1908445_1909570_-|DUF445-domain-containing-protein
MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYITTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEKLSIHLSRIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
>NZ_CP038229.1|WP_000290301.1|1908032_1908377_-|YlbF/YmcA-family-competence-regulator
MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
>NZ_CP038229.1|WP_001791795.1|1907440_1907539_-|hypothetical-protein
MPFDSLAVLITTEIAFPTEIFEKYQRTLQIKF
>NZ_CP038229.1|WP_000238226.1|1905953_1907150_-|exonuclease-SbcCD-subunit-D
MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDIALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKISSNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHIGVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGRHFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQVREEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDESPLVNEFSAELLVDQAVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMRGEQNDN
>NZ_CP038229.1|WP_000031108.1|1916351_1916504_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>NZ_CP038229.1|WP_001251224.1|1916528_1917128_-|glucosamine-6-phosphate-isomerase
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>NZ_CP038229.1|WP_000181394.1|1917286_1917757_-|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>NZ_CP038229.1|WP_000379980.1|1917761_1918889_-|tRNA-epoxyqueuosine(34)-reductase-QueG
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>NZ_CP038229.1|WP_000590809.1|1919039_1919762_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>NZ_CP038229.1|WP_000649907.1|1919754_1921212_-|ABC-transporter-permease-subunit
MKCLIRFILVLGLLISSAMVYINPTAHAEQDQTWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLIVAAALYFVLTFVLTRIMNMIEGRLNASD
>NZ_CP038229.1|WP_169449292.1|1921469_1922531_-|PTS-transporter-subunit-IIC
MSNANNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFITIYSNDIYKFEVPKQ
>NZ_CP038229.1|WP_001808146.1|1923023_1924343_-|ISL3-like-element-IS1181-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPDYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRHSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKAVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>NZ_CP038229.1|WP_000110011.1|1932921_1933368_-|peroxide-responsive-transcriptional-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>NZ_CP038229.1|WP_045176936.1|1933464_1934415_-|2-hydroxyacid-dehydrogenase
MKVVGLNRMREVETELQQRFSDLDFKFYKKASEIPESDLADLDILVGYDGGINEAFLQRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSKVIRHAYLDVLENEPLKPNHELYELENVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDTKKGY

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Crispr_ID: NZ_CP038229_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038229_3

2160645-2160730

Orphan

Consensus_repeat	Method
CCAACTGATTTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038229_3

>merge|NZ_CP038229|3|2160645-2160730|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGGGCCAACTGATGTTTGCGTATCATTAGT

>NZ_CP038229|3|3|2160645-2160730|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG
CCAACTGATGTTTGCGTATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038229.1\|WP_000958531.1\|2178654_2179719_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP038229.1\|WP_000927340.1\|2156337_2158470_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP038229.1\|WP_000347896.1\|2170430_2171240_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP038229.1\|WP_001802298.1\|2148739_2148844_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_001141006.1\|2179866_2181309_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP038229.1\|WP_045177717.1\|2171428_2172337_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP038229.1\|WP_045177732.1\|2147149_2148241_+\|lytic-regulatory-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_000648723.1\|2158915_2160022_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP038229.1\|WP_045177727.1\|2151264_2152047_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP038229.1\|WP_001292149.1\|2158481_2158916_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP038229.1\|WP_001237506.1\|2182203_2183547_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP038229.1\|WP_000334463.1\|2152278_2154084_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP038229.1\|WP_000884746.1\|2184427_2185615_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NZ_CP038229.1\|WP_000047255.1\|2183725_2184409_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP038229.1\|WP_138271856.1\|2168114_2169470_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP038229.1\|WP_000636857.1\|2181631_2182105_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP038229.1\|WP_000894032.1\|2169496_2170429_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP038229.1\|WP_000083807.1\|2154764_2156303_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP038229.1\|WP_001792784.1\|2149523_2149682_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038229.1\|WP_045177730.1\|2150340_2151198_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635

Protein	Function_ID	Function_description	E-value
NZ_CP038229.1\|WP_000958531.1\|2178654_2179719_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NZ_CP038229.1\|WP_000927340.1\|2156337_2158470_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.17174e-68
NZ_CP038229.1\|WP_000347896.1\|2170430_2171240_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP038229.1\|WP_000636857.1\|2181631_2182105_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NZ_CP038229.1\|WP_001141006.1\|2179866_2181309_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.08461e-81
NZ_CP038229.1\|WP_045177717.1\|2171428_2172337_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	7.66556e-146
NZ_CP038229.1\|WP_000884746.1\|2184427_2185615_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	4.55468e-149
NZ_CP038229.1\|WP_000648723.1\|2158915_2160022_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP038229.1\|WP_045177727.1\|2151264_2152047_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.61229e-104
NZ_CP038229.1\|WP_001292149.1\|2158481_2158916_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP038229.1\|WP_001237506.1\|2182203_2183547_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.92638e-43
NZ_CP038229.1\|WP_000334463.1\|2152278_2154084_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP038229.1\|WP_000047255.1\|2183725_2184409_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP038229.1\|WP_138271856.1\|2168114_2169470_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP038229.1\|WP_000894032.1\|2169496_2170429_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_CP038229.1\|WP_000083807.1\|2154764_2156303_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP038229.1\|WP_045177730.1\|2150340_2151198_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	4.25215e-56

>NZ_CP038229.1|WP_000648723.1|2158915_2160022_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP038229.1|WP_001292149.1|2158481_2158916_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP038229.1|WP_000927340.1|2156337_2158470_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP038229.1|WP_000083807.1|2154764_2156303_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP038229.1|WP_000334463.1|2152278_2154084_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP038229.1|WP_045177727.1|2151264_2152047_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNQRFSMMMLE
>NZ_CP038229.1|WP_045177730.1|2150340_2151198_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNKASTYTKDVINQLREKGYKVFLATGRSHSEIYQLVPQDFVVDGIISSNGTIGEVDGHTIFKHGLSLTQVKQIVDLAKQQHIYYEVFPFEGNRVALKEDETWMRKMIHSQDPINGVSHSEWSSRQDALAGKIKWVSDFPEGEYSKIYLFSSNLEKITTFRDELKQNQVQLHISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGIRQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP038229.1|WP_001792784.1|2149523_2149682_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP038229.1|WP_001802298.1|2148739_2148844_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP038229.1|WP_045177732.1|2147149_2148241_+|lytic-regulatory-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP038229.1|WP_138271856.1|2168114_2169470_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGTQKYLSYLKSTVDVNFEGLKIALDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP038229.1|WP_000894032.1|2169496_2170429_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP038229.1|WP_000347896.1|2170430_2171240_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP038229.1|WP_045177717.1|2171428_2172337_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELIELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP038229.1|WP_000958531.1|2178654_2179719_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP038229.1|WP_001141006.1|2179866_2181309_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP038229.1|WP_000636857.1|2181631_2182105_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP038229.1|WP_001237506.1|2182203_2183547_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_CP038229.1|WP_000047255.1|2183725_2184409_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP038229.1|WP_000884746.1|2184427_2185615_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKLMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKTGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	2463814-2463838	0	1.0
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	140912-140936	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	140970-140994	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	342597-342621	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1352775-1352799	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1748876-1748900	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	782537-782561	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	787974-787998	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1067320-1067344	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1446768-1446792	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1446826-1446850	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1960400-1960424	1	0.96
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	796586-796610	2	0.92
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	796704-796728	2	0.92
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	944690-944714	2	0.92
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1357209-1357233	2	0.92
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1405092-1405116	2	0.92
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	NZ_CP038229.1	1661193-1661217	2	0.92

1. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 2463814-2463838, mismatch: 0, identity: 1.0

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctttgttg	Protospacer
*************************

2. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 140912-140936, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

3. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 140970-140994, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

4. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 342597-342621, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaatttctctttgttg	Protospacer
************ ************

5. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1352775-1352799, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

6. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1748876-1748900, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

7. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 782537-782561, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

8. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 787974-787998, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

9. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1067320-1067344, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctatgttg	Protospacer
******************* *****

10. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1446768-1446792, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

11. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1446826-1446850, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

12. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1960400-1960424, mismatch: 1, identity: 0.96

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaattctctgtgttg	Protospacer
******************* *****

13. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 796586-796610, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcatttcgaaattctctgtgttg	Protospacer
**** ************** *****

14. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 796704-796728, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcatttcgaaattctctatgttg	Protospacer
**** ************** *****

15. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 944690-944714, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttagaaattctctgtgttg	Protospacer
******** ********** *****

16. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1357209-1357233, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttatcgaaattctctgtgttg	Protospacer
****** ************ *****

17. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1405092-1405116, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttcttttcgaaaatctctgtgttg	Protospacer
************* ***** *****

18. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to position: 1661193-1661217, mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctctatgttg	Protospacer
******* *********** *****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP038229_1	1.1\|246595\|25\|NZ_CP038229\|CRISPRCasFinder	246595-246619	25	LC371242	Escherichia phage EcS1 DNA, complete sequence	15447-15471	2	0.92
NZ_CP038229_3	3.1\|2160671\|34\|NZ_CP038229\|CRISPRCasFinder	2160671-2160704	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NZ_CP038229_3	3.1\|2160671\|34\|NZ_CP038229\|CRISPRCasFinder	2160671-2160704	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 1.1|246595|25|NZ_CP038229|CRISPRCasFinder matches to LC371242 (Escherichia phage EcS1 DNA, complete sequence) position: , mismatch: 2, identity: 0.92

tttcttttcgaaattctctttgttg	CRISPR spacer
tttctttacgaaattctttttgttg	Protospacer
******* *********.*******

2. spacer 3.1|2160671|34|NZ_CP038229|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **

3. spacer 3.1|2160671|34|NZ_CP038229|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

719405 : 727225

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|719405_720461_-	HAMP domain-containing histidine kinase	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|720460_721147_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|721121_721595_-	DoxX family protein	NA	NA	NA	NA
WP_001093553.1\|721936_722377_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_045177943.1\|722656_723241_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|723339_724053_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_045177940.1\|724056_724476_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	1.1e-06	28.7
WP_000446724.1\|724477_725146_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1\|725496_726090_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217790.1\|726073_727225_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	4.6e-23	35.7

DBSCAN-SWA_2

739197 : 753984

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1\|739197_740256_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197271.1\|740606_741149_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_045177934.1\|741828_742746_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	8.2e-07	22.0
WP_031835073.1\|742836_742938_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|743015_744521_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|744861_745362_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_045177931.1\|745381_746248_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|747048_747447_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|747409_749515_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|749632_750604_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|751117_751273_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|751311_752283_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|752269_753226_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616839.1\|753222_753984_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

844091 : 887458

Staphylococcus_phage(70.59%)

holin,tail,capsid,integrase,portal,terminase,plate,head

attL 843999:844058|attR 887691:887780

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
843999:844058	attL	NA	NA	NA	NA
WP_001145728.1\|844091_845141_-\|integrase	site-specific integrase	A1KWY3	Staphylococcus_virus	1.6e-203	100.0
WP_086097265.1\|845202_846132_-	DUF5067 domain-containing protein	Q4ZAM2	Staphylococcus_virus	5.0e-137	99.4
WP_000524999.1\|846150_846612_-	hypothetical protein	A0A2I6PEK4	Staphylococcus_phage	3.7e-85	98.7
WP_000429766.1\|846624_846954_-	helix-turn-helix transcriptional regulator	A0A2I6PEN2	Staphylococcus_phage	3.2e-54	100.0
WP_001115060.1\|847114_847306_+	helix-turn-helix transcriptional regulator	A0A2I6PEL6	Staphylococcus_phage	2.3e-28	100.0
WP_000939498.1\|847394_847538_+	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_000642492.1\|847527_847737_-	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_001148557.1\|847793_848573_+	phage antirepressor KilAC domain-containing protein	M1RZB2	Staphylococcus_phage	4.1e-132	92.6
WP_000187184.1\|848573_848798_+	hypothetical protein	A0A0F6N4M2	Staphylococcus_phage	3.2e-34	100.0
WP_000395455.1\|848988_849219_-	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
WP_000594789.1\|849289_849511_+	hypothetical protein	B2ZYU8	Staphylococcus_phage	8.7e-32	100.0
WP_000048124.1\|849503_849665_+	DUF1270 family protein	C7F7L3	Staphylococcus_phage	1.9e-20	100.0
WP_169449259.1\|849757_850087_+	hypothetical protein	A0A2I6PEL3	Staphylococcus_phage	6.9e-33	98.6
WP_001667298.1\|850067_850328_+	DUF1108 family protein	Q4ZAD8	Staphylococcus_virus	2.2e-42	98.8
WP_031911831.1\|850342_850822_+	siphovirus Gp157 family protein	A0A0H4J328	Staphylococcus_phage	3.1e-82	99.4
WP_001288248.1\|850821_851595_+	AAA family ATPase	W5RAN1	Staphylococcus_phage	2.1e-141	100.0
WP_000704708.1\|851624_852176_+	hypothetical protein	W5R977	Staphylococcus_phage	3.4e-101	100.0
WP_169449260.1\|852188_852860_+	hypothetical protein	A7TWM9	Staphylococcus_phage	1.7e-126	99.6
WP_000371250.1\|852965_853823_-	DUF4393 domain-containing protein	Q4ZBL8	Staphylococcus_phage	9.5e-159	100.0
WP_000190224.1\|853887_854658_+	conserved phage C-terminal domain-containing protein	W5R8N2	Staphylococcus_phage	1.4e-116	100.0
WP_000803065.1\|854667_855447_+	ATP-binding protein	W5RAN3	Staphylococcus_phage	1.2e-144	100.0
WP_000237153.1\|855440_855602_+	hypothetical protein	D2JGK6	Staphylococcus_phage	4.5e-22	100.0
WP_001123673.1\|855614_855836_+	DUF3269 family protein	A7TWN4	Staphylococcus_phage	1.3e-35	100.0
WP_000049784.1\|855846_856251_+	DUF1064 domain-containing protein	A7TWN5	Staphylococcus_phage	7.1e-72	100.0
WP_001187242.1\|856255_856441_+	DUF3113 family protein	W5R8N4	Staphylococcus_phage	1.4e-27	100.0
WP_001140281.1\|856441_856810_+	hypothetical protein	Q9B0F5	Staphylococcus_virus	5.3e-50	93.4
WP_000131379.1\|856813_857056_+	hypothetical protein	A0A0F6N3E1	Staphylococcus_phage	1.9e-40	98.8
WP_001105611.1\|857070_857436_+	hypothetical protein	A7YGS3	Staphylococcus_virus	1.6e-59	95.0
WP_001065123.1\|857428_857680_+	DUF1024 family protein	Q4ZBT3	Staphylococcus_virus	7.1e-38	96.4
WP_000028424.1\|857669_857843_+	hypothetical protein	A0A2H4PQJ2	Staphylococcus_phage	1.8e-24	100.0
WP_000454994.1\|857843_858125_+	hypothetical protein	A0A2I6PDX3	Staphylococcus_phage	8.5e-48	100.0
WP_000889683.1\|858125_858287_+	hypothetical protein	A0A2I6PDW5	Staphylococcus_phage	2.4e-23	100.0
WP_025920701.1\|858301_858835_+	dUTPase	E0Y3R2	Staphylococcus_virus	1.3e-94	99.4
WP_169449261.1\|858871_859060_+	DUF1381 domain-containing protein	A0A2I6PEH2	Staphylococcus_phage	1.5e-24	98.4
WP_001125015.1\|859034_859235_+	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_169449262.1\|859237_859411_+	transcriptional regulator	A1KX88	Staphylococcus_virus	2.4e-21	94.7
WP_000990005.1\|859411_859558_+	hypothetical protein	B2ZYX7	Staphylococcus_phage	2.2e-15	100.0
WP_031901125.1\|859581_860004_+	DUF1492 domain-containing protein	Q4ZDW2	Staphylococcus_virus	1.4e-73	99.3
WP_001003271.1\|860190_860631_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.8e-74	100.0
WP_000169944.1\|860617_861895_+\|terminase	PBSX family phage terminase large subunit	Q8SDU9	Staphylococcus_phage	3.0e-249	100.0
WP_031784784.1\|861905_863441_+\|portal	phage portal protein	Q4ZDV9	Staphylococcus_virus	3.5e-289	99.2
WP_001133043.1\|863447_864443_+\|capsid	minor capsid protein	E0Y3K7	Staphylococcus_virus	3.4e-184	100.0
WP_001646693.1\|864515_864686_+	hypothetical protein	Q4ZDN0	Staphylococcus_virus	1.3e-22	98.2
WP_049317484.1\|864794_865415_+	DUF4355 domain-containing protein	Q8SDU6	Staphylococcus_phage	6.4e-64	99.5
WP_000438511.1\|865428_866403_+\|capsid	phage major capsid protein	E0Y3L0	Staphylococcus_virus	2.2e-183	100.0
WP_001114086.1\|866424_866712_+	hypothetical protein	S4V6D9	Staphylococcus_phage	1.4e-45	98.9
WP_000208960.1\|866720_867053_+\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001268312.1\|867049_867352_+	hypothetical protein	A4ZFB6	Staphylococcus_virus	1.1e-50	100.0
WP_001017815.1\|867351_867699_+	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_031900480.1\|867710_868094_+	hypothetical protein	E0Y3L5	Staphylococcus_virus	1.3e-67	99.2
WP_000002577.1\|868112_868694_+\|tail	phage major tail protein, TP901-1 family	A0A0F6N3L8	Staphylococcus_phage	4.9e-106	100.0
WP_169449263.1\|868756_869122_+\|tail	phage tail protein	A0A0F6N4J9	Staphylococcus_phage	8.1e-59	99.2
WP_000105585.1\|869151_869496_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	7.2e-57	99.1
WP_169449264.1\|869512_872977_+	hypothetical protein	S4V989	Staphylococcus_phage	2.1e-257	98.2
WP_073421355.1\|872989_873937_+\|tail	phage tail family protein	A0EWU0	Staphylococcus_virus	1.8e-182	99.4
WP_031883664.1\|873945_875847_+\|tail	phage tail protein	Q4ZDU3	Staphylococcus_virus	0.0e+00	99.8
WP_029625624.1\|875861_877772_+	hypothetical protein	Q8SDT4	Staphylococcus_phage	0.0e+00	98.9
WP_029625623.1\|877771_879595_+\|plate	phage baseplate upper protein	A0A0H3U4S6	Staphylococcus_phage	6.7e-312	97.7
WP_000705910.1\|879594_879972_+	DUF2977 domain-containing protein	Q9FZY7	Staphylococcus_virus	1.2e-60	100.0
WP_000782200.1\|879975_880149_+	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000466784.1\|880189_880489_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_073421358.1\|880625_882524_+	glucosaminidase domain-containing protein	Q8SDT1	Staphylococcus_phage	0.0e+00	99.8
WP_169449265.1\|882536_883709_+\|plate	BppU family phage baseplate upper protein	Q8SDT0	Staphylococcus_phage	3.2e-197	99.7
WP_015978410.1\|883714_884110_+	hypothetical protein	A0A2H4PQP8	Staphylococcus_phage	2.1e-68	100.0
WP_094756967.1\|884165_884603_+\|holin	phage holin	Q8SDS8	Staphylococcus_phage	2.0e-72	99.3
WP_169449266.1\|884583_886029_+	SH3 domain-containing protein	A0A0H3U310	Staphylococcus_phage	1.5e-294	99.2
WP_000448197.1\|886418_887006_+	hypothetical protein	Q4ZBG7	Staphylococcus_virus	5.4e-97	100.0
WP_000971220.1\|887002_887458_+	hypothetical protein	B7T0L3	Staphylococcus_virus	2.7e-72	100.0
887691:887780	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1042117 : 1050590

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1042117_1042600_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010406.1\|1042586_1043711_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1043714_1044419_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1044418_1044682_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1044683_1045355_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032745.1\|1045347_1047537_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.6e-141	39.8
WP_000483713.1\|1047515_1049000_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030815.1\|1048992_1050021_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.9e-61	41.1
WP_000238668.1\|1050023_1050590_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.7e-29	40.1

DBSCAN-SWA_5

1598612 : 1606924

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1598612_1599398_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924220.1\|1599523_1600414_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062177.1\|1600423_1601770_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683933.1\|1601883_1602984_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624570.1\|1602986_1603664_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1603794_1604901_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217262.1\|1605124_1606924_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.0e-53	36.3

DBSCAN-SWA_6

1676399 : 1685442

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1676399_1676918_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_045177803.1\|1676939_1679213_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.4e-63	29.0
WP_000749795.1\|1679415_1681695_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1681969_1682230_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1682248_1683388_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1683410_1684436_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005767.1\|1684437_1685442_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_7

1811056 : 1886676

Staphylococcus_phage(96.55%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_169449288.1\|1811056_1817617_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	0.0e+00	100.0
WP_000836465.1\|1817942_1818254_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_086095116.1\|1818275_1820699_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	100.0
WP_001025061.1\|1820986_1822168_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_045173807.1\|1822277_1823231_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764423.1\|1823227_1823791_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	2.2e-103	100.0
WP_000757543.1\|1823910_1824312_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1824883_1825711_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1825713_1825833_-	hypothetical protein	NA	NA	NA	NA
WP_001196345.1\|1825944_1826946_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	3.1e-185	100.0
WP_001008549.1\|1827067_1827532_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159035.1\|1827544_1828726_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
WP_000493888.1\|1828736_1829369_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.4e-113	100.0
WP_045177230.1\|1829375_1830419_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.1e-198	100.0
WP_045177232.1\|1830899_1832402_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221179.1\|1832924_1833239_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989117.1\|1833238_1834531_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	100.0
WP_000163235.1\|1834548_1834944_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	6.3e-73	100.0
WP_001032833.1\|1835238_1836093_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1836368_1836593_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1836791_1837262_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1837374_1837818_+	competence protein ComK	NA	NA	NA	NA
WP_001030463.1\|1837804_1838248_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	3.7e-58	100.0
WP_001168908.1\|1838543_1839179_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1839619_1840333_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_169449289.1\|1840592_1840895_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1841150_1841516_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623478.1\|1841512_1841866_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_000453314.1\|1842248_1843082_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366163.1\|1843293_1844202_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1844326_1845520_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109906.1\|1845891_1847484_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_072384924.1\|1847736_1848483_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	4.4e-144	100.0
WP_078161169.1\|1848487_1848961_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.2e-83	98.7
WP_000718107.1\|1849026_1849284_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_045177246.1\|1849280_1850282_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.2e-190	100.0
WP_169449290.1\|1850286_1851765_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.7e-288	99.8
WP_072384923.1\|1851923_1852379_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	2.7e-80	100.0
WP_072384920.1\|1852681_1853332_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	7.2e-58	100.0
WP_049296627.1\|1853412_1854408_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	3.3e-78	100.0
WP_045177256.1\|1854483_1855110_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	6.2e-99	100.0
WP_045177258.1\|1855150_1855492_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	2.9e-58	100.0
WP_045177260.1\|1855592_1856165_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.7e-26	100.0
WP_045177261.1\|1856362_1856920_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	3.0e-81	100.0
WP_000375477.1\|1857293_1857470_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1857480_1857864_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1858467_1858611_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|1858813_1858909_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|1859031_1859133_+	hypothetical protein	NA	NA	NA	NA
WP_001037045.1\|1859480_1859858_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000831218.1\|1860378_1864491_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
WP_169449291.1\|1865340_1866540_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.1e-228	99.5
WP_000028669.1\|1866532_1868089_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
WP_001791797.1\|1868252_1868387_-	hypothetical protein	NA	NA	NA	NA
WP_001038688.1\|1868451_1869171_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.1e-131	100.0
WP_001038759.1\|1869321_1870038_-\|protease	serine protease SplE	A0A2H4PQN5	Staphylococcus_phage	1.1e-131	100.0
WP_011447030.1\|1870139_1870247_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1\|1870195_1870915_-\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038865.1\|1871035_1871755_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.1e-131	100.0
WP_001039444.1\|1871812_1872535_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001039435.1\|1872659_1873367_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	2.6e-130	100.0
WP_001092763.1\|1874330_1874897_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_072384919.1\|1875370_1876069_-	BsaG protein	A0A2H4PQH0	Staphylococcus_phage	1.3e-116	100.0
WP_000581552.1\|1876065_1876827_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1876823_1877516_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1877538_1878912_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1878921_1879440_-	enterotoxin	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1879455_1880700_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_045176870.1\|1880692_1883686_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	100.0
WP_000432510.1\|1883750_1883894_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	3.8e-20	100.0
WP_045176869.1\|1884755_1885739_-	beta-channel forming cytolysin	A0A2H4PQH7	Staphylococcus_phage	2.1e-186	100.0
WP_000473596.1\|1885740_1886676_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP038229

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection