CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP046176	Bacteroides dorei strain DSM 17855 chromosome, complete genome	3 crisprs	PD-DExK,csa3,DinG,PrimPol,RT,cas9,cas1,cas2,DEDDh,cas3,WYL	0	9	1	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046176_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046176_1

154934-155022

Orphan

Consensus_repeat	Method
GTGTCAGAGTGTCTAAGTTTAGT	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_CP046176_1

>merge|NZ_CP046176|1|154934-155022|CRISPRCasFinder
GTGTCAGAGTGTCTAAGTTTAGTGTCAGAGTCTGTATTAAAAGTGTCAGAGTTGGTATCTAAGTTGGTGTCAGAGTGTCCAAGTTTAGT

>NZ_CP046176|1|1|154934-155022|CRISPRCasFinder
GTGTCAGAGTGTCTAAGTTTAGT	GTCAGAGTCTGTATTAAAAGTGTCAGAGTTGGTATCTAAGTTG
GTGTCAGAGTGTCCAAGTTTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046176.1\|WP_007834517.1\|148024_149662_+\|ATP-binding-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834536.1\|156823_160528_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834515.1\|142937_148043_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379062
NZ_CP046176.1\|WP_007834529.1\|152021_152528_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007854916.1\|167133_167631_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834526.1\|150919_151336_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_008767280.1\|156335_156551_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378971
NZ_CP046176.1\|WP_149948574.1\|161075_161312_-\|PriCT-2-domain-containing-protein	unknown	unknown	gnl\|CDD\|378030
NZ_CP046176.1\|WP_007834513.1\|142703_142910_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_CP046176.1\|WP_007834533.1\|152531_154598_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|350795
NZ_CP046176.1\|WP_007834544.1\|163639_163963_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|226079
NZ_CP046176.1\|WP_007834508.1\|140315_140714_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834547.1\|165690_166989_+\|glycoside-hydrolase-family-88-protein	unknown	unknown	gnl\|CDD\|369381
NZ_CP046176.1\|WP_007834545.1\|163952_165068_+\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NZ_CP046176.1\|WP_007834510.1\|140729_141923_+\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NZ_CP046176.1\|WP_007834555.1\|168647_168866_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834524.1\|149664_150768_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_CP046176.1\|WP_007834553.1\|167643_168258_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|379226
NZ_CP046176.1\|WP_007834528.1\|151521_151965_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834543.1\|162094_163237_-\|phage-integrase-SAM-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|271185

Protein	Function_ID	Function_description	E-value
NZ_CP046176.1\|WP_007834515.1\|142937_148043_+\|ATP-binding-protein	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	1.02156e-05
NZ_CP046176.1\|WP_007834553.1\|167643_168258_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	0.00500615
NZ_CP046176.1\|WP_008767280.1\|156335_156551_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|378971	pfam12844, HTH_19, Helix-turn-helix domain. Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.	5.22099e-06
NZ_CP046176.1\|WP_149948574.1\|161075_161312_-\|PriCT-2-domain-containing-protein	gnl\|CDD\|378030	pfam08707, PriCT_2, Primase C terminal 2 (PriCT-2). This alpha helical domain is found at the C terminal of primases.	1.49659e-05
NZ_CP046176.1\|WP_007834513.1\|142703_142910_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.74381e-06
NZ_CP046176.1\|WP_007834533.1\|152531_154598_+\|AAA-family-ATPase	gnl\|CDD\|350795	cd18037, DEXSc_Pif1_like, DEAD-box helicase domain of Pif1. Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.4384e-42
NZ_CP046176.1\|WP_007834544.1\|163639_163963_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|226079	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only].	7.02557e-10
NZ_CP046176.1\|WP_007834547.1\|165690_166989_+\|glycoside-hydrolase-family-88-protein	gnl\|CDD\|369381	pfam07470, Glyco_hydro_88, Glycosyl Hydrolase Family 88. Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.	7.18755e-61
NZ_CP046176.1\|WP_007834545.1\|163952_165068_+\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	6.70637e-18
NZ_CP046176.1\|WP_007834510.1\|140729_141923_+\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	1.38505e-05
NZ_CP046176.1\|WP_007834524.1\|149664_150768_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.03481e-18
NZ_CP046176.1\|WP_007834543.1\|162094_163237_-\|phage-integrase-SAM-like-domain-containing-protein	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.50311e-16

>NZ_CP046176.1|WP_007834533.1|152531_154598_+|AAA-family-ATPase
MQNTQIDPLNHEQQLAYELVANTNSSFFLTGRAGSGKTTFLHNVQKLVGKQFITLAPTGVAAILAGGDTIHSFFGLPMEICTPGTCGKMNEAKILTLIHADSIIIDEVSMVKCDVMDAIDYTMRKALRNNTPFGGKQMIFVGDMFQLPPVVRQGPEKDLLKDLYHTEDFFFYKSNAIKRMRLVKIEFQKVYRQDDAHFLHILENVRMNKVTPEDITHLNDRVRVPNEEDGAVITLASINKTADKINLQRLEEIEAEEFVYEGTVDGTFEEKRFPVELKLRLKVGAQVMFTRNDLQKRWANGTLGKVTKLTKDEISVTLNNGETYVVPCCSWESYSYDYNKEERKMKKELTGTFTQYPLKLAWAITIHKSQGMTFDKLSLDLSRGMFAAGQLYVALSRVRTLEGLYLSKNIIPQYAHTSREVLTYASEYNNEQQIDNEIESGKAVYSALQQNDYDEAAKQYLMLVTKKAENGDFKEAMQQAKRFLDILVCDEHLYGLIEDIPENLLHTSHWAPKFIAALLSLYAQKYKDALILIGEVLERHQCAEALYIKSRALAKLERYTEADDTNCQLANVFEMATPDAKVLFMIAILNEMHIGDPGLDLMRKLVEARPKYDLGILALRTLMQRHGLQLDKLSDNNCELVDLFNSDATEEEFLAELKVCREKAPKAITYLIRRIKKQVFNEEQPVDE
>NZ_CP046176.1|WP_007834529.1|152021_152528_+|hypothetical-protein
MASLAKAINKDLFDKILPTFGNPRVHVPVWDEGQKMFLCEEYESGNGHRYYKGVRFCDRIVIVEKVGLYHTWTYIDSIEVYAFNGTRLELVQKRDYDKTFRNEEFIRQESETMVCNYFEGVLKAQRSAMPKEQLEAQAKSIIEGCYKSFLDNDFNTRLTQILPQLEQK
>NZ_CP046176.1|WP_007834528.1|151521_151965_+|hypothetical-protein
MNTSLALVAAKALPALSGSSLTYNPEKNVFLTLGYTSAAGNTYYKAIRFSNRLAVYYHIGEGYAHTFLNGITLFAWNGQKANIIAQKFWGGCNWRCFNERTAKEESIVMLKDFLAGQAKAMGSIIADSQLLAFSRNMIEETQQKLLQ
>NZ_CP046176.1|WP_007834526.1|150919_151336_+|hypothetical-protein
MKQATNSSKNSMNKKASQKQFATNRKAEANAHHKVNKKWELIKNTPRYRSALAKEVCETITKKIEIEVLNGILLNLNIRSQAKTPNVQNRILRRIIEKRQAQANHKKHGRTNDLTLMYVSIICTSRCMEAIRKKRVAA
>NZ_CP046176.1|WP_007834524.1|149664_150768_+|WYL-domain-containing-protein
MQRKNLFDGESYKAEFAIITYRWLMSRRWVTNADIMADRLGCSIEELPANLSNCDGYGELKKIVCIVKKAIRDKLGVHNKNVDDCFEEDGNNKNRRFRYIGKDNDPLAEMRNAKVINNLRQYWKFCQGSAGFFPKSWLEYFFKDCQDLLDIKVKRQKGEQVISASLDRILTNIEYLPSLYEAITNKMVMEIDYKPFEEEVITLMFHPHYLKEYNGRWHLFGHADGRVPEYGYNIALDRIQSKPRERGKVEYVPAPKHFYDAFFKDIVGVSHRKDAHKEHIVIRARSLYIYKLMDTKPLHQSYAVVKSFGTYDDGEYAEFSIDVEPNNEFYGRILQMGAGLEVVSPDSVRKEIAQRVRDLANLYPHEK
>NZ_CP046176.1|WP_007834517.1|148024_149662_+|ATP-binding-protein
MDTQQLNGFKTMNLYRNPFASPTEEAIGTDFIGRKSVLKKMHEYIINADKISNYHIVGLPRIGKSSLLKAFKTMIQENHYSHDLVVLYISLDECDNSNDMWRIIGKGIRKELKKQFHSSDKYTNFIDELDFEDVDENNIDYEYVCSVARCMKASGFLGLILIDEFDNFSTIATKGTVGQVRTLFSGSEYGLRAVVASRRMVERIEKEVEGALNSNVSILASTFVNGYKLKAFNEDDMKDYWVSIEEKIGVAVSNRYKEETDYYVGTHPCLLNLLNGSFWAEKETKDYICDDDSNLKLSEELINKLHDSFNWAVWRDMEKWQLLRSLILSTWGPDDEIPNSELSELERYGIIDKSQFLSESSGPIRIAISRYFTEWMNLKRYVLPFGDEWSKAEGNMRKIVKCFCDDMYQGYESKMISHLETKNANTLEKNVDPRFTAKGRFDAMKNKMSKAINKYPDMSSSIIDYSDPSDLPEIFFKREWSWFQQIFSKTWDEWREKFATMNEIRNIKLHNNQGVPQVRIELAKKYCHEVNERIESFLSIRGIII
>NZ_CP046176.1|WP_007834515.1|142937_148043_+|ATP-binding-protein
MSCINFNEISSLITKWLQNSSIESLQFTDGKLVEKAIGIVLYPHQDNEDSLFLQLCALNFLNAVIKTEAFKNKLSNDLIKSNAARLIKTVDVLKNDEISYYYSKEEYCLYIKLGSIVFSFHHVPLTTDVLKASFAPLIKWPGIRLQRIAQPLLNYALSMNNEIETTPMDINDVIIDEVVDSSSVNGFNSEKIFNNENNATEDNGIVSVSAQRKNVLTAIEKNTIKQRVLSTIDSYCSPDSEGWYDLVEIAPKLKNNGIDYTEYGFKKLTLFLEAVFENSMQRRNEGTMVYLKFPLNNSQANSNSQCILKKVDNNQDCYDILSGVQVGDNVEINSFGNIKAGIISVLNKHFVQLELKGGRSIRIKCDSIDSIESAFLFNNLIDLSFANDIIKNVLLSEGLYTSSLIRTNATITMAESRRIWLVTDDGKNASCSKVSLIGINKENLIKGQRVFAFPFKGEKAYCVLMEMTYYEVFECFKKLISQKKDNSKDIQRAQIFSLLRFILENTNAPENQTKIKQLKKQLKSFISSPSLSLDSYADDDTSDTIASVITSTNNQEDDSAEVQAANNNIEEMIDKEPNKRQSETSNVEIYKPESTSLEGPKVIGYINLDEIRDPKKKNKNASEEEKTKDTVMVDSKSEMLPSMGKILRMGPMYGWISQNNQEDNLYFNTTELVSYAGIIEAPCVGDEVIFTLGQNARGAMAVCIHKQCARETIEELIEKTQRYDPKTCARLKKYIEDFDNLFTNTIETNENLTYYLNRIGVNIKMPFSPNDAEKLFAEKLSAEEYAKGINLLIDEVIKTDPSKSYNLFLRSFSYTKSHKMYDVSESLIKKALVVFKKQDGKTKYFKGLLKTINTLSNRIEITEKSIDNIINSIGQSSVHLPLYVKNAILNHKDFNGITPDQETIRTGLYKEEYIDEVKDYIKQNNADDLAYLTLIKLQLAFHIVGYNPMEDVLNFLLSRAKNILAIGDEKLYSEVRYLLRLYYRNRNFDTNLDYTVGLYLMTLGEYTPSDIEMYTSMWRVREVRAGYKLADLFKKAVESDVDNKLDLAMLSYSNPAIRQRILKEYESLGKNFDSIDEFPSLLKELNNRYIQYSTDPRINFMSFISYLQTSTILLNSEMNIIENDFDKIVSLVTDFNIGQKYTSILNAYKNIDQKIANITSKLSSNPTEIGYETLLPSLSLLKNNIYSKFVEIEQRVNPTITISILESVVLEDSQSAELKVEIRNSSDSARDVHINRLKAFGGDLTEANTVNIDVRLSADEEKTISIELHMCDRVFNENAAEVEFEIDYDDIFIATDQRVHETKIEGRTIRFNKETFTEIDNKFRHASGGEELEAGDSMFYGRESLIVNIQNAILNGSKNQIAIYGQKRSGKSSLLNQIIGRLESTENGSVICGKFSLQGLPDEESNPVNWILRNIAYSLLRGIRKSRIKNIDKSILELFKTESDAFTALREFIEYINTIVELQNSHFVILIDEFTYLYQLIKDGKVSEDFMRRWIALIETPDINLQTIVAAQDTLPHFMNESYASNYFNKFSKEPLSYLSREEAIQLIKDPIKNVVFLNHAEELIYEYTSGSAFFTQIFCTRLVDYLNFKKSRTVGKEEIETVANRLCTGTDRLEPSTFECLTKEADGSDFYESDNKRILKAIAEQTRAGGHVNMEDLDVDMPQEHIKEVLNNLYSRRVISKQGEDYSINVKLFVKWILNN
>NZ_CP046176.1|WP_007834513.1|142703_142910_+|helix-turn-helix-transcriptional-regulator
MENLNRIKGALADAGKTGVWLASQLGKDPVTVSKWCTNTTQPDLQTLAKISDLLKVNIKDLLVNRNIY
>NZ_CP046176.1|WP_007834510.1|140729_141923_+|relaxase/mobilization-nuclease-domain-containing-protein
MIAKASTIPHGANAIRYSVNKDRADTVKANLLPDDISPEAMYGRMMLVQKMFAEKINKGRPLGRNVIRIEISPAEEESRNWKMDDWVHLANEFIHVFDSIDLSEKTKRASSKQTNLKGSQYIVALHRDSKSGILHLHIDANRVDMDGKINDSHKIGKRAVMAANIINEKRGWVQSEEIGIQHRQEITNYCMKILREMDKFSWQQYAMELTKRGYKVHLQEDDKGKVYGYSIKRGSSNYKSSVLGVGRNLTPSKIEATWAKLYQQERKSESTKSIPQQIRSADITFISQPVIKHYDIATDEYHSYHVDIPEAADNIIQQECSLEEAHPLAKIEEIQHTALLLFAGYLDAATSMAVSSGGGGSDTGGWGRDKDEDGLKWARRCARMANSMCKRRRGLHR
>NZ_CP046176.1|WP_007834508.1|140315_140714_+|hypothetical-protein
MKKKKNISNEADEENDKKVIKRTLRLEARVTEQEYARAKELAKTCGLSMSNYVRRTALGQHPRQRLSEREVEALCSLTDARGDLIRIAAAVKSIQADKRAMYFSDTRFVEQWVRAATQLINRWSQIENYLTE
>NZ_CP046176.1|WP_008767280.1|156335_156551_-|helix-turn-helix-transcriptional-regulator
MEKEMINRLKIVLAEEQKSSKWLAEQLGKDRATVSKWVTNTMQPDARNLLRIAEALNIDAGRLLNQKHLKK
>NZ_CP046176.1|WP_007834536.1|156823_160528_+|hypothetical-protein
MKLIKANNLKRWADTLEIRGLLSELIRRLVHVTKPHLSKVYIPTEESTHSAGWDGIVISEDNDTYLPAGTCLIEMGTNENVAAKANDDYTKRTKDSLGFEKEECTFVFITPREWPKAPSWETDKNKLNEWKKVKVITAVELEDWLSYYPSVALWLTEKLNISHRVKIQSIESYWHQWSTNDKGQQLCYSVAIGGRKESVKELLEKTENHIAIDVCSHSIEESLAFVVAAILQYGDDSLKNRVLFAKDNETTGLLASQCSNMVIISSGDDKNIDPNENCLVYVAHPSSRSKSGVSITLQTPEPDDFINALKESGFNETQARQLCSDTGRSTAILRRKLGFERNNPDWAKPENISRLLPAFLIGRWLNNQEGDKKLIEELSGIEYCQFENLIQTFAKGNDSPLGLIDSLWYVISPFDAINYAIDFITPQYLDRFSAIIDKVANDIDLDDKKAATTDSLFWQKHNTKYSYYAKEGVFLTLVLLALRGDKNAQLIPWVDEKVRAILNINTLEWWFSYCKHNLISLLAEASPQVFIQRIEDDVMSDNSIIREMFRINFEHTSLWGNSSHYGYVLSALEDLAWPAENLSRISRILFELSPLGKKEGYAGNPFESLCKIYCLWMPKTKATIEQCFMVLESMAEEFRPFVFRLCRCLVNYSRQSQSINGRIMRWRYFGEDVKAVTMDEFLTALTATVRMLIQNCDYSNDAIECMLETATAPDLPAHLRKEVQDAISSNIDFLKGKNKFCDKIREKIYHFEEARDSDWCISDDEMNWLKNLLEAILPDDIIEANLWKFKAFLPVHELHRREDDIRKWTEKQLSFRVAAVKELYKRIGFDGLRKIVEKSEDKYQTGLAFAKFKTTYPMIDFVLNEGFDNQLLAGFFVSLFNTNKERYWKVVKKYNNRNDILISIGTNEELTRFVETLPEEAKENYWKTVSVWCYSDDTLNIMTEQLLKVGRYGDVLSLLRHVSYGGKDIPVAPAFNALQGWLNNIKTPEFEQYRHDAEEILEYLDKNPNVKDEQIVSLELLLSEIFHLDSDCRLYHSIYTEPKNLLELISFAYRGDEDFDDKTYSDSERNIGLLSLRFIKGHVKSCPGLTKNGTLDEDALMKYADEFMSLAKREKYFHAAKIVFGQLLGNIPDREDYPQNVLCKLLTKYSEHGRDKSILNSFRCQFFNNRGMTSRLPYDGGRIERTRSEKYKKYADKTRYTYPDVASIFDSLSRDHEFDAYRMDNQAELAKIGY
>NZ_CP046176.1|WP_149948574.1|161075_161312_-|PriCT-2-domain-containing-protein
MDITYYYNDWIAIGNIIKNMFDEEGRALFHKVSSFYPNYDYDETDSEYSAMIVGQYRYNSDRLFEIAAKYGLIPPIKK
>NZ_CP046176.1|WP_007834543.1|162094_163237_-|phage-integrase-SAM-like-domain-containing-protein
MFNYSKDGVVVSTVLGARTINKEGKYPVKIKGYYQKRPKYDSIGICMTKEEWNKLPGSKSFEYRKIKQAIESCFSLVRMNVEALAEKGIFSFNTLNLRLGKATGDTLNSVIRAKIEELKSEDRIGTMQFFKCTLVMVEEVGGKDIPFSAITVEWLQKCEKLWSKTRSVSTIGMHMRNIRTLMNEAKRAGVIKESQYPFGKGLFEIKTGIGRKKGLTKKQLKAIFDYKSGNETTNRYKDLWIFIYLCNGINPTDMLKLKFSDIVDGEICFVRQKTERTTKNRKEIRATISVQMQAVIDKWGNKPLPDNYIFPYMKGNETAIEAKAITRDVVKRINKRMKLIGEELGIGNITTYTARHSYATVLKRSGVNISYISESLGHTD
>NZ_CP046176.1|WP_007834544.1|163639_163963_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MNIYTEDEALIELLEVGCTNDKRYKRLPKDVIKGYIKAYNHLRAAKRIEDLFRIGSLHYERLKGDLKDFESVRCTGRWRLIFKSSTIDSSLIITDIELIEISNHYGD
>NZ_CP046176.1|WP_007834545.1|163952_165068_+|HigA-family-addiction-module-antidote-protein
MATKFKLNDCVPCIAIHPGEIIKDELDAREMKQKELASFMGMPTSVLNDIIKGRRAITPEVAVLLQEILSIDASYWLSLQNQYDIDKANINTKIIERKRNIEIWKIISQYCSIKCFEKLNIIGTKISENIKTIYSIFGVTSVEELITLYSQEKEVSYFKKSERLKSEPINIFSWKYYVFYESSKIQCDTKFSNDNLNNLIDELNHLFVINKDTIDTTKKILSRYGIKFIIVPKFDKTPIDGFSFWQGENPTIVLTLRLNRIDNYAFALLHEIYHVYMHLFNNREQKYISIEGAEINKCEEEANKFAKYSLISKDLWSAFLKQHSMISPHAMQMKIKQFAHQHNINEAIVLGFYQHDINLYSIKSSISREIK
>NZ_CP046176.1|WP_007834547.1|165690_166989_+|glycoside-hydrolase-family-88-protein
MVKSYACAGILLFAIGLFPLMAQDNTVAKEMAIKIADRIIASTVYEFKDVKTGKVYTSLDNVALNPDIRVNSKYLNWHYTNGVTNMALMELGDKIQNRKYEDYVLKNMKFIFDKTNQSYFHRLYDKTFREGGWRAVPRLTWHMIYRNKRLDDNGPMGASLITLNQRHPDEAFQQYVETTNHHLMVSEPRLADGTIARLWPHENTVWADDAFMAVSFISRMGEVTGEKKYFDDAANQILNYTRYLWCPEKQIYYHCYHTDNKEHGVAHWSRANGWIFMATADLLARMPEDHPMRDDVIKNFQMQASGVARYQGKNGLWHQLLDKADSYEEITGTSMFVFGIAKGVKEGWLHPDFIYVAWQGLKGMLSKISENGDVTAICVGTGIMPSTVFYYNRPTQENDPMGEGPVLRALVEMIDAPKYTEISANDQYDKIK
>NZ_CP046176.1|WP_007854916.1|167133_167631_-|hypothetical-protein
MIKYLITIVLTIALCCSCDREDFSADPTIMPPATQTGANTFGCLIDGWVYTGQRYDSDDKASYYPARNEDEKAIVSIDVRVDNNASISFNIIDPKEKDITIYSISEGASDDQTIYTDVIFKNENNQEEKLEDGIINITRFDLNNRIISGTFEGERIKEGRLDLKF
>NZ_CP046176.1|WP_007834553.1|167643_168258_-|outer-membrane-beta-barrel-protein
MLLYSSVLYAQFGTSERSILSLQTGPTFYTGKLIGVAVHSSSLRNGIGWSGSYTYLIGNKPAIRVGFGVLYQGSRYTNDMPNSSDKIQTHYFAPQFSLHWLKQQFSLYFTTGTGYQLYQDNSTVYDKPRKVSMNKWAANFGIGGEYRAFTHWGVSARINYILAYSGEYSVRYHDKEWMVQPHYPMKGADDISQLGFSVGINYHF
>NZ_CP046176.1|WP_007834555.1|168647_168866_+|hypothetical-protein
MKKEFIRRYGWTLLGIVAGMVGGYLYWRYVGCSTGTCPITSSPVNSSIWGAAMGGLLLSSFIPERKEIKKEE

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Crispr_ID: NZ_CP046176_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046176_2

387869-388169

Orphan

Consensus_repeat	Method
ATGTCCTGAATGTGGTAAGGAAATAAATGAA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_CP046176_2

>merge|NZ_CP046176|2|387869-388169|CRISPRCasFinder
ATGTAGTGAATGTGGTAATATGATTTCTGACAAATCAGAAAATTGTATCTATTGTGGCTCACCTATATCAATTTCATTAAAAACATTAATACCTTGCCCCGAATGTGGGACATTAATAGAAGAAACGGCTGAAAAATGCACAAAATGTGGTTTTCCCTTTATTCCTAAAAAGCAGTTGGAATGTCCTGAATGTGGTAAGGAAATAAATGAAGGAGTAGAAGAATGTCCTGAATGCGGTTTTCCTTTTATTTCTTCCAAAGAACCAATTAGATGTCCTGAATGTGGTAAGGAAATAAGTGAA

>NZ_CP046176|2|2|387869-388169|CRISPRCasFinder
ATGTAGTGAATGTGGTAATATGATTTCTGAC	AAATCAGAAAATTGTATCTATTGTGGCTCACCTATATCAATTTCATTAAAAACATTAATACC
TTGCCCCGAATGTGGGACATTAATAGAAGAA	ACGGCTGAAAAATGCACAAAATGTGGTTTTCCCTTTATTCCTAAAAAGCAGTTGGA
ATGTCCTGAATGTGGTAAGGAAATAAATGAA	GGAGTAGAAGAATGTCCTGAATGCGGTTTTCCTTTTATTTCTTCCAAAGAACCAATTAG
ATGTCCTGAATGTGGTAAGGAAATAAGTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046176.1\|WP_007834928.1\|397524_399582_-\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397
NZ_CP046176.1\|WP_007834921.1\|393170_393779_+\|porin-family-protein	unknown	unknown	gnl\|CDD\|379226
NZ_CP046176.1\|WP_032936095.1\|385689_385932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834907.1\|386416_386749_+\|DUF2693-domain-containing-protein	unknown	unknown	gnl\|CDD\|371293
NZ_CP046176.1\|WP_007834922.1\|393851_396314_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514
NZ_CP046176.1\|WP_007834899.1\|383520_383811_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NZ_CP046176.1\|WP_007834895.1\|382183_383524_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271185
NZ_CP046176.1\|WP_007834913.1\|388437_388932_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379090
NZ_CP046176.1\|WP_007834919.1\|391666_392671_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|316042
NZ_CP046176.1\|WP_007834909.1\|386812_387481_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|365969
NZ_CP046176.1\|WP_007834917.1\|390174_391050_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834905.1\|386075_386381_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007834932.1\|401193_402414_+\|3-deoxy-D-manno-octulosonic-acid-transferase	unknown	unknown	gnl\|CDD\|224436
NZ_CP046176.1\|WP_007834926.1\|397079_397550_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|319971
NZ_CP046176.1\|WP_032936014.1\|380532_381156_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_002558131.1\|381799_382021_+\|DUF2795-domain-containing-protein	unknown	unknown	gnl\|CDD\|378655
NZ_CP046176.1\|WP_007834924.1\|396361_397072_+\|phosphatase	unknown	unknown	gnl\|CDD\|213992
NZ_CP046176.1\|WP_007834930.1\|399663_401181_+\|glutamate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234953
NZ_CP046176.1\|WP_007834893.1\|381164_381728_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl\|CDD\|376665
NZ_CP046176.1\|WP_007834901.1\|384069_385140_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046176.1\|WP_007834928.1\|397524_399582_-\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	5.91002e-116
NZ_CP046176.1\|WP_007834921.1\|393170_393779_+\|porin-family-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	5.05277e-21
NZ_CP046176.1\|WP_007834899.1\|383520_383811_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.000903852
NZ_CP046176.1\|WP_007834909.1\|386812_387481_+\|recombinase-family-protein	gnl\|CDD\|365969	pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see pfam02796.	4.20475e-31
NZ_CP046176.1\|WP_007834932.1\|401193_402414_+\|3-deoxy-D-manno-octulosonic-acid-transferase	gnl\|CDD\|224436	COG1519, KdtA, 3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane].	1.77122e-67
NZ_CP046176.1\|WP_007834895.1\|382183_383524_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.71986e-28
NZ_CP046176.1\|WP_007834913.1\|388437_388932_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379090	pfam13248, zf-ribbon_3, zinc-ribbon domain. This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR. pfam12773.	0.000248206
NZ_CP046176.1\|WP_007834922.1\|393851_396314_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0
NZ_CP046176.1\|WP_007834919.1\|391666_392671_+\|AAA-family-ATPase	gnl\|CDD\|316042	pfam13481, AAA_25, AAA domain. This AAA domain is found in a wide variety of presumed DNA repair proteins.	2.4921e-12
NZ_CP046176.1\|WP_007834926.1\|397079_397550_+\|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	9.11738e-65
NZ_CP046176.1\|WP_002558131.1\|381799_382021_+\|DUF2795-domain-containing-protein	gnl\|CDD\|378655	pfam11387, DUF2795, Protein of unknown function (DUF2795). This family of proteins has no known function.	4.12508e-13
NZ_CP046176.1\|WP_007834924.1\|396361_397072_+\|phosphatase	gnl\|CDD\|213992	cd07437, PHP_HisPPase_Ycdx_like, Polymerase and Histidinol Phosphatase domain of Ycdx like. PHP Ycdx-like is a stand alone PHP domain similar to Ycdx E. coli protein with an unknown physiological role. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. It has also been shown that the PHP domain functions in DNA repair. The PHP structures have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel. YcdX may be involved in swarming.	2.11482e-129
NZ_CP046176.1\|WP_007834930.1\|399663_401181_+\|glutamate--tRNA-ligase	gnl\|CDD\|234953	PRK01406, gltX, glutamyl-tRNA synthetase; Reviewed.	0
NZ_CP046176.1\|WP_007834893.1\|381164_381728_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl\|CDD\|376665	pfam01923, Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.	1.40263e-82
NZ_CP046176.1\|WP_007834907.1\|386416_386749_+\|DUF2693-domain-containing-protein	gnl\|CDD\|371293	pfam10902, WYL_2, WYL_2, Sm-like SH3 beta-barrel fold. WYL_2 is a family of Sm-like SH3 beta-barrel fold containing domains. WYL is named for three conserved amino acids found in a subset of domains of this superfamily. These residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.24541e-20

>NZ_CP046176.1|WP_007834909.1|386812_387481_+|recombinase-family-protein
MGNYVAYLRQSTTKQERSGLGIEAQRDIISSFVKEGVILAEYVETESGRKSDRPKLHEALALCRKTNSILIVAKLDRLSRNVAFTSKLLESDVEIIFCDFPQANRLILHIISSIAEYEANLISQRTRQSLKAKKERGVKLGKSENLMDKHNEAIAHSNQTNRIKAQNNANNMRAVALLRSMIKEGLTISQMTKQLNEQGFVSSKGCKFQIVQVQRLIQRYVA
>NZ_CP046176.1|WP_007834907.1|386416_386749_+|DUF2693-domain-containing-protein
MQAIILSSNTAIRAEVITLRTNARKIDGISKAVLVEQLKEKLKSGKIVKFAYLKSNGEVRIAFGTTNHDFVKDKVYGWGASRENYATTAYFDLEKCGWRSFRWENLIAVF
>NZ_CP046176.1|WP_007834905.1|386075_386381_+|hypothetical-protein
MKRYNKQQVMKDAHRLYNNDFQRRGRSWSECLKAAWSWERDAVRTREEKAVKLDAMIAASWATHNARKNESVHKNEFEGLSADAVSWAMGYNRGNGFYCGD
>NZ_CP046176.1|WP_032936095.1|385689_385932_-|hypothetical-protein
MTEKEKKERTVIHLYIKENDTHHYFGSIANIFEYFSPEELGITYGSLRNYGLSYKNPYQNSKCIIRKGILLSKSGNRGKK
>NZ_CP046176.1|WP_007834901.1|384069_385140_-|hypothetical-protein
MNDFYLSLKDEHKPTIIYTTYSNIDNINNRFRLIYVFNEPIRSNEYYRGIANTIVYNIQKEIEGFDLKDKTCLNASQQFAGNGNDNVVYYYNDNIFCFTDFGFDENYLSNSDSILKKERKNNIQTDLKSPIGNTEFMKDFWGMSYKRNEEIFIRKYAEIYPFIEATPLPETDSDTPYILLPDNYVKIARYWYKEPLTKGDGTIVYKSHAVKLKSGHRRKLLYDGCLLRKIMLPEITMEHLLYCLVCERRYYVDNQDKVITNKILYQIAKDAWNDTKRSIKPKKEERQFVVNPKYCEKYGVNKQAARNIATKMLLDLQLKQLYDTNLSVKENLESLKNQGIKIGKSSLYNWVKSQKI
>NZ_CP046176.1|WP_007834899.1|383520_383811_-|helix-turn-helix-domain-containing-protein
MSYELIDNETMNKLFLNIEVLSRQVKELSEKSKFTEKEIYTNSEIRELLGVQDKLIRKYRDERKLGFHKEGDKFWYTRKDILQFLSHNHYEAYAYN
>NZ_CP046176.1|WP_007834895.1|382183_383524_+|tyrosine-type-recombinase/integrase
MGRVKSLSNSGSFVLRKDNQNAKGEYQVYIQYSLDRKIAKDKTDVWVKEKEWNDKAQKVRSVHPQSVRLNKILDKKKNDIDALILDFPSEKRLTIDVLRSMVRGEYNVNEEKNQDFVQLAVDNLEALYKTEKIGISVRDNGLNGLKLFRTFLLEELGEDSISVADMTEDIVDSYIIWRKNKRNNINATINKTLTPLMKAAKLAARKGLMEASVADAISEKYLPIKTKLSDEDAEDEDVRYLTKEQLSKFVALYNVVKYPRTREYMDMFLFAFHACGLRFSDILTLQWMHVDLEKHKLKKKLYKGKVPHEIALNDAALKILEQWKMKNRSNRFVFALLPDDFNLADEEELNRMRINKNTPIKVSLKALGHKIGGLSFNLTMHVARHTFAVFALNNGVDVHKVSCLLAHSSVMVTEKVYAKFLPETLQKEVETKLNFDFTPDYNTAVD
>NZ_CP046176.1|WP_002558131.1|381799_382021_+|DUF2795-domain-containing-protein
MYWTLELASKLEDAPWPATKDELIDYAMRSGAPLEVIENLQEMEDEGEIYESIEDIWPDYPSKEDFFFNEEEY
>NZ_CP046176.1|WP_007834893.1|381164_381728_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MKKSMIYTKTGDKGTTSLVGGTRVPKTHIRLEAYGTVDELNSYLGLLQTYLTDEEDKQIIFRVQNKLFSVGSYLATDQTQIDLRMESRIEDEDIRMLEQAIDVIDNELPPLNAFILPGGDRGAAVGHICRTVCRRAERRILALAEECDIDARVTAFVNRLSDYLFILTRKLNHLTKTDEIFWDKSCK
>NZ_CP046176.1|WP_032936014.1|380532_381156_+|hypothetical-protein
MFFLHRIWNWCSRFRHRCGYGVHSPSDFFLITSVVYEKYHYYAYRVLKERGFPAYLPHYRRKVNRLLFRLVNYFRPKSLIEVGIGNGASIGYMRAACHTMNSVTLKGRDWTKTSRQLEEKLSEVHTLDCLHIGHTPFYKEVFELVLPYAGPRSCFIVGGIHESREKRKWWEQIVTSESTGITFDLYDIGLVFFDKARYKQHYIVNFL
>NZ_CP046176.1|WP_007834913.1|388437_388932_+|zinc-ribbon-domain-containing-protein
MSLIKCPNCKATVSDKATVCPKCGKTTQYSTKSAKIAIWIFVIFFGLSGVCIVYDKFFKFSTVSLTTKNAQYHSFICKADAEGDHKITLYDNTFYYEVKMHYADEWLRVAKGTYEVKEFISNKKKKIGVFVRVEQKPDLSFLVIDLSEMNLYWAEQYIGKVEIE
>NZ_CP046176.1|WP_007834917.1|390174_391050_+|hypothetical-protein
MKNILITLFLLNINISVFAQRTNAHGQYMVKTATWKSYGGQSSFKMDLGYYLNGNLKEVTKNYELNGKKYRDTYSISYNSKGERILKFVRYVNGKQNFSAKALYNFNENNLISNINWYAPSKNRLVQTFQMSYNENRELVKLIKTTSENMDEDWSSTTITTINWDNNNIVSDKTIDVGEEYGGEANFVYYPESEVRNNTNLNFNFLIFYSYGRDYMSDIVFGTEWCGKNTNLILKGDKDELDRYKHLQPEFRGHYEYEKNGDLITKLRYIAPRVGKEHNYVYGTLTLEYVH
>NZ_CP046176.1|WP_007834919.1|391666_392671_+|AAA-family-ATPase
MNNNMLCGCLTANQAMEKALALPPIKALYETFWYENELCIFFAEANVGKSLYAMQMAEHIAQERKVMYLDYELSLSQFRSRYTNDETGVPYQFSDNLFRPSLRIEQVSDDREVEERLFKKIEEGVRMGIKTYVVDNITYLCGKLDQGIEATRIMKRLSAMKHTYGLSLLVIAHTKKRNSKKEIEADDLAGSKRLMNFCDSSFALGKSREDSKTIYLKQIKVRQGENKHGKDNVILYRIVKDDNFPRFVEEGCSEEEKLLKPSKSEDKGILKAKMKILHEEGLSNRAIAKELGIAEGTVRNWLKELEEVVNVSTEPSSMVQEESEAEYVEYEEVA
>NZ_CP046176.1|WP_007834921.1|393170_393779_+|porin-family-protein
MKKIISVLMVAVCLMMAAPAQAQLHFGVKGGLNLSKVSFSKSDLKGDNKTGWFIGPMAEFTLPIIGIGADVAALYSQTELAAKGYSTDAKLKTIEIPVNLKWSFGLGSMLGAYIAAGPQFGFNIGNKKGFMNYDLKKNNTSFNVGAGVKLIRHLQLGVNYNFALGHTATLYADPNIILDGKPLTQDVKIKNNTWQVSLAYLF
>NZ_CP046176.1|WP_007834922.1|393851_396314_+|primosomal-protein-N'
MKKFVDVIVPLPIANQYTYSLPQEMEEMVQIGCRVIVPFGKKKFYTAIVTNVHYAAPEGYETKDIAEVLDSSPVLLPKQYEFWQWLAEYYLCTLGDVYKAAIPSGMKLESETLVEYNPDFETTAPLPEKEQKILDLLSRDTEQCVTQLEKNSGLKNVLTVIKSLLDKEAIFVKEELKRNYKPRTEARVRLVNGEADEAYLQRLFNELSRAPKQLMILMKYVELSGWVTKGYALKEVTKKELLEKSGGSVAVFNGLVEKKVFEVYHQEIGRLDKGILDTGDINPLNIAQQQAYSNILQCFREKNVCLLHGVTSSGKTEIYIHLIQEVLKTGKQVLYLLPEIALTTQITERLKRVFGHRLGIYHSKFPDAERVEIWQKQLGEKSYDVILGVRSSIFLPFRNLGLVIIDEEHENTYKQQDPAPRYHARSSAIMLASMFKAKVLLGTATPGVETYFNATSGKYGLVELKERYKDIRLPHIELVDIKELAHQKRMQGPFSPVLVKQIKEALERKEQVILFQNRRGFAPMIECHTCGWVPKCKNCDVSLTYHKGLNQLTCHYCGYTYQVPRSCPACGGVELMHRGFGTERIEDDIKLIFPEAKVARMDLDTTRTRTAYEKIITNFELGKTDILIGTQMVSKGLDFDHVSVVGILNADTMLNFPDFRSYERAFQLMAQVAGRAGRKNKQGLVILQTKSPDLPVIHQVIHNDYEQLYYDQLAERQMFKYPPYYRLIYVYLKHRKEDVLDLAADTMAAQLRSGLGDRVLGPDKPPVARIQTLFIKKMIVKVEQNASIKKVRDYLLAVQRAILEDERFRSLLVYYDVDPQ
>NZ_CP046176.1|WP_007834924.1|396361_397072_+|phosphatase
MKIELDVHTHTIASGHAFSTLQEMAQAAAGKGLKVLGITEHSPGIPGTCHPIYFRNLHVVPRRMYGVELLLGAEINILDGKGNLDLDEDYMKMLDIRIAGIHSLCYEYGTIEENTHGMVQAISNPFIHIISHPGDGTAALHFEPMVLAAKEHHTLLEINNSSLKPTRNKPDARENNLTILRLCKKYEVPVILGSDAHISFDIARYDNLYELLQLTGFPEELIMNRDVKSFKEYLHL
>NZ_CP046176.1|WP_007834926.1|397079_397550_+|low-molecular-weight-phosphotyrosine-protein-phosphatase
MKRILFVCLGNICRSSSAEEVMRTLIKKEGLEHEIEVDSAGILSYHRGELPDSRMRMHASRRGYNLTHRSRPVCTEDFYHFDMIIGMDDRNIEDLMERAPDLETEKKIHRMTDYCRVKVADYVPDPYYGGAQGFENVLDILEDACAGLLTSLVPDN
>NZ_CP046176.1|WP_007834928.1|397524_399582_-|HDIG-domain-containing-protein
MRSFKTSKRFSYKNLIYKSLIFIATVSVIVYFLPNEGKFNYQFDINKPWKYGLLQASFDFPIYKNDLQVQKEQDSILADYQPYFQIDKEAEKNVLSKLREDYNKTLRHSLPGTDYVRYIERTLKALYEDGIIAGNDLKRMEEDSIIAIRLVDKNVATSRFIDQLYTVKEAYEYLLNADTAHYKKKILQQCNLNDYITPNLVYDEEKSEAAQKDLLSNISWANGFVLNGQKIIDRGEIVDEQTYNILESLRKEWEKRSDSVQEKRLTLAGQILYVGIFLFCFMAYLELFRADYYERKGTLTLLFALIVFFPVLSSIMVEQNLSSIYVVPFAMIPIIVRVFLDSRTAFMAHVTIILLCSITLRFPHEFILLQVVAGMVAIYSLRELSQRSQLLRTALVVFISYALLYFAFELIHEDDLTKLNTRMYIYFMINGILLLFAYPLLFLLEKIFGFTSDVTLVELSNINNSLLREMSEVAPGTFQHSLQMANLAAAAANKIGGKSQLVRTGALYHDIGKMVNPAFFTENQSGVNPHKSLSYEQSAQVIISHITDGLKLAEKHNLPKVIKDFISTHHGRGLTKYFYISYKNEHPDEEVDQEKFRYPGPNPFTKEQAVLMMADSVEAASRSLPEYTEESISTLVDKIIDTQVSEGYFKECPITFKDIATVKALFKEKLKTMYHTRISYPELKK
>NZ_CP046176.1|WP_007834930.1|399663_401181_+|glutamate--tRNA-ligase
MSERKVRVRFAPSPTGALHIGGVRTALYNYLFARQHGGDLIFRIEDTDSNRFVPGAEEYIIESFKWLGINFDEGVSFGGNYGPYRQSERRDIYKKYVQVLLDSDKAYIAFDTPAELDAKRQEISNFQYDASTRMSMRNSLTLPKEEVDALIADGKQYVVRFKIEPNEDVHVHDIIRGEVVINSSILDDKVLYKSADELPTYHLANIVDDHLMEVSHVIRGEEWLPSAPLHVLLYRAFGWADTMPEFAHLPLLLKPDGNGKLSKRDGDRLGFPVFPLEWHDPKTGEVSSGYRESGYLPEAVINFLALLGWNPGNDQELMSLDELVKLFDLHRCSKAGAKFDFEKGKWFNHEYILKKSNEEVAGLFMPILKEHGIEVPMDKVVTVVGLMKDRVSFIKDLWETCKFFFVAPTEYDEKTRKKRWKEDSPERMLELADVLAALDDFSLENQEAVVMKWIEDKGYHLGNIMNAFRLTLVGEGKGPHMFDISAVLGKEETLRRIRRAVEVLK
>NZ_CP046176.1|WP_007834932.1|401193_402414_+|3-deoxy-D-manno-octulosonic-acid-transferase
MIYNLVIYIYLFGVKVVGLFSAKPAKMVKGHREVFDILRNKIDKNARYIWFHAASLGEFEQGRPLIERIRKEHPEYKILQTFFSPSGYEVRKNYQGADLVCYLPFDTPRNVRRFVELANPCMVFFIKYEFWQNYLNELHRRGIPTYSVSSIFRPNQIFFRWYGKRYSEVLRTFAHLFVQNEVSKKLLATIGVTDVTVVGDTRFDRVLDICHQAKQLPLVEKFKGGSLTFVAGSSWGPDEDIFIKYFNEHPEMKLVIAPHVVSDSHLKEILDKVKRPCIRYTEATEENVTQADCLIIDCYGLLSSIYRYGEISYIGGGFGVGIHNVLEAAVYGIPVIFGPNNKKFREAQHLLEQKGGFEVTGYDDFKRLMDKFLSDKACLQQAGKAAGNYVNHNAGALEKIMKDITL

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP046176_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046176_3

1534364-1535560

TypeII

Consensus_repeat	Method
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	PILER-CR
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CRISPRCasFinder

15 spacers

cas2,cas1,cas9

The CRISPR arrays of NZ_CP046176_3

>merge|NZ_CP046176|3|1534364-1535560|PILER-CR,CRISPRCasFinder
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACTTAAGGCTGCTGATCATTGTCAACATCGCGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACCAGTGACCAGCGCACGTCGCACCCCTGAACGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACTCATCAAAACTGGAATAGAATATGAAAAGAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACTTGAATCATCACCTAACCAATGAAGACGAAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACGCACGTAGGTGCGCAAAGGCAGGTTCTATCGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACAAACAAACAATAACAAATTGAACATATGGAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACTGCTCGTTAAGCGCATCACGGGTTGTTATTGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACAGACGGCGAACGCCAATGACCAGCCTAATAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACACTTTTACAGTAACTCTCAATGGGAGAAACGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACAAGCCCAATCAAGCAAAGGAACAGCGTGAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACCATAACGACACACAATTAATAAGGTAAACGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACACAAGTATACCAATGAAAAGATATCTTTTTGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACGCATACGCTGCTTCGACGTTGGTGAAGGCAGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACCATCAGTGCCGTTTGCTTACTGCTTTTGGGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAACTGAATACCCATTTGATTGTGATAAAAAATGTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCATAAC

>NZ_CP046176|3|1|1534364-1535560|PILER-CR
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TTAAGGCTGCTGATCATTGTCAACATCGC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CAGTGACCAGCGCACGTCGCACCCCTGAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TCATCAAAACTGGAATAGAATATGAAAAGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TTGAATCATCACCTAACCAATGAAGACGAA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	GCACGTAGGTGCGCAAAGGCAGGTTCTATC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AAACAAACAATAACAAATTGAACATATGGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TGCTCGTTAAGCGCATCACGGGTTGTTATT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AGACGGCGAACGCCAATGACCAGCCTAATA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	ACTTTTACAGTAACTCTCAATGGGAGAAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AAGCCCAATCAAGCAAAGGAACAGCGTGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CATAACGACACACAATTAATAAGGTAAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	ACAAGTATACCAATGAAAAGATATCTTTTT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	GCATACGCTGCTTCGACGTTGGTGAAGGCA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CATCAGTGCCGTTTGCTTACTGCTTTTGG
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TGAATACCCATTTGATTGTGATAAAAAAT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCATAAC

>NZ_CP046176|3|3|1534364-1535560|CRISPRCasFinder
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TTAAGGCTGCTGATCATTGTCAACATCGC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CAGTGACCAGCGCACGTCGCACCCCTGAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TCATCAAAACTGGAATAGAATATGAAAAGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TTGAATCATCACCTAACCAATGAAGACGAA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	GCACGTAGGTGCGCAAAGGCAGGTTCTATC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AAACAAACAATAACAAATTGAACATATGGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TGCTCGTTAAGCGCATCACGGGTTGTTATT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AGACGGCGAACGCCAATGACCAGCCTAATA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	ACTTTTACAGTAACTCTCAATGGGAGAAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	AAGCCCAATCAAGCAAAGGAACAGCGTGA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CATAACGACACACAATTAATAAGGTAAAC
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	ACAAGTATACCAATGAAAAGATATCTTTTT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	GCATACGCTGCTTCGACGTTGGTGAAGGCA
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	CATCAGTGCCGTTTGCTTACTGCTTTTGG
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCACAAC	TGAATACCCATTTGATTGTGATAAAAAAT
GTTGTTTCCAATGGTTCAAAGATACTAATTTGAAAGCAAATCATAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046176.1\|WP_032936679.1\|1539421_1542673_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274948
NZ_CP046176.1\|WP_005848345.1\|1536223_1536409_-\|KTSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|379296
NZ_CP046176.1\|WP_007837578.1\|1547201_1548038_+\|deoxyribonuclease-IV	unknown	unknown	gnl\|CDD\|179214
NZ_CP046176.1\|WP_007837560.1\|1527436_1531951_+\|CRISPR-associated-protein-Cas2	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|375967
NZ_CP046176.1\|WP_005848349.1\|1533922_1534255_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP046176.1\|WP_007837572.1\|1536824_1537415_+\|epoxyqueuosine-reductase-QueH	unknown	unknown	gnl\|CDD\|376894
NZ_CP046176.1\|WP_007837576.1\|1544124_1545306_+\|AhpC/TSA-family-protein	unknown	unknown	gnl\|CDD\|239264
NZ_CP046176.1\|WP_007842555.1\|1525291_1525621_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379200
NZ_CP046176.1\|WP_007837565.1\|1532990_1533923_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP046176.1\|WP_007837552.1\|1521164_1522520_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240543
NZ_CP046176.1\|WP_005848347.1\|1535577_1536159_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046176.1\|WP_007837573.1\|1537411_1539229_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378964
NZ_CP046176.1\|WP_007837551.1\|1519339_1521202_+\|SLC13-family-permease	unknown	unknown	gnl\|CDD\|238535
NZ_CP046176.1\|WP_007837579.1\|1548361_1549726_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|237087
NZ_CP046176.1\|WP_007837553.1\|1522756_1525258_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|163244
NZ_CP046176.1\|WP_007837558.1\|1525653_1527252_+\|ClC-family-H(+)/Cl(-)-exchange-transporter	unknown	unknown	gnl\|CDD\|238504
NZ_CP046176.1\|WP_007837550.1\|1518743_1519151_-\|hotdog-fold-thioesterase	unknown	unknown	gnl\|CDD\|182337
NZ_CP046176.1\|WP_007837562.1\|1531965_1532964_+\|virulence-RhuM-family-protein	unknown	unknown	gnl\|CDD\|379118
NZ_CP046176.1\|WP_007837575.1\|1542684_1544106_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|373012
NZ_CP046176.1\|WP_007837577.1\|1545869_1547159_+\|porin	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP046176.1\|WP_032936679.1\|1539421_1542673_+\|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	5.64045e-175
NZ_CP046176.1\|WP_007837578.1\|1547201_1548038_+\|deoxyribonuclease-IV	gnl\|CDD\|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	4.01654e-165
NZ_CP046176.1\|WP_007837560.1\|1527436_1531951_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|375967	pfam18541, RuvC_III, RuvC endonuclease subdomain 3. Cas9 proteins are abundant across the bacterial kingdom, but vary widely in both sequence and size. All known Cas9 enzymes contain an HNH domain that cleaves the DNA strand complementary to the guide RNA sequence (target strand), and a RuvC nuclease domain required for cleaving the noncomplementary strand (non-target strand), yielding double-strand DNA breaks (DSBs). The crystal structures of type II-A and II-C Cas9 proteins highlight the features in Cas9 enzymes that support their function as RNA-guided endonucleases. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. The RuvC domain forms the structural core of the nuclease lobe, a six-stranded beta sheet surrounded by four alpha helices, with all three conserved subdomains (I, II, III) contributing catalytic residues to the active site.	1.25228e-57
NZ_CP046176.1\|WP_005848349.1\|1533922_1534255_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.96144e-29
NZ_CP046176.1\|WP_007837572.1\|1536824_1537415_+\|epoxyqueuosine-reductase-QueH	gnl\|CDD\|376894	pfam02677, DUF208, Uncharacterized BCR, COG1636.	2.45919e-92
NZ_CP046176.1\|WP_007837576.1\|1544124_1545306_+\|AhpC/TSA-family-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	7.15858e-34
NZ_CP046176.1\|WP_007842555.1\|1525291_1525621_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|379200	pfam13463, HTH_27, Winged helix DNA-binding domain.	2.13113e-11
NZ_CP046176.1\|WP_007837565.1\|1532990_1533923_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	4.20112e-122
NZ_CP046176.1\|WP_007837552.1\|1521164_1522520_-\|MATE-family-efflux-transporter	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	7.49367e-123
NZ_CP046176.1\|WP_005848345.1\|1536223_1536409_-\|KTSC-domain-containing-protein	gnl\|CDD\|379296	pfam13619, KTSC, KTSC domain. This short domain is named after Lysine tRNA synthetase C-terminal domain. It is found at the C-terminus of some Lysyl tRNA synthetases as well as a single domain in bacterial proteins. The domain is about 60 amino acids in length and contains a reasonably conserved YXY motif in the centre of the sequence. The function of this domain is unknown but it could be an RNA binding domain.	2.19458e-05
NZ_CP046176.1\|WP_007837573.1\|1537411_1539229_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	3.90695e-15
NZ_CP046176.1\|WP_007837551.1\|1519339_1521202_+\|SLC13-family-permease	gnl\|CDD\|238535	cd01115, SLC13_permease, Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.	4.64533e-59
NZ_CP046176.1\|WP_007837579.1\|1548361_1549726_-\|TrpB-like-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|237087	PRK12391, PRK12391, TrpB-like pyridoxal phosphate-dependent enzyme.	0
NZ_CP046176.1\|WP_007837553.1\|1522756_1525258_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|163244	TIGR03385, Coenzyme_A_disulfide_reductase, CoA-disulfide reductase. Members of this protein family are CoA-disulfide reductase (EC 1.8.1.14), as characterized in Staphylococcus aureus, Pyrococcus horikoshii, and Borrelia burgdorferi, and inferred in several other species on the basis of high levels of CoA and an absence of glutathione as a protective thiol. [Cellular processes, Detoxification].	2.09046e-149
NZ_CP046176.1\|WP_007837558.1\|1525653_1527252_+\|ClC-family-H(+)/Cl(-)-exchange-transporter	gnl\|CDD\|238504	cd01031, EriC, ClC chloride channel EriC. This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked proton utilization. As shown for Escherichia coli EriC, these channels can counterbalance the electric current produced by the outwardly directed virtual proton pump linked to amino acid decarboxylation. The EriC proteins belong to the ClC superfamily of chloride ion channels, which share a unique double-barreled architecture and voltage-dependent gating mechanism. The voltage-dependent gating is conferred by the permeating anion itself, acting as the gating charge. In Escherichia coli EriC, a glutamate residue that protrudes into the pore is thought to participate in gating by binding to a Cl- ion site within the selectivity filter.	5.49812e-103
NZ_CP046176.1\|WP_007837550.1\|1518743_1519151_-\|hotdog-fold-thioesterase	gnl\|CDD\|182337	PRK10254, PRK10254, proofreading thioesterase EntH.	6.67312e-23
NZ_CP046176.1\|WP_007837562.1\|1531965_1532964_+\|virulence-RhuM-family-protein	gnl\|CDD\|379118	pfam13310, Virulence_RhuM, Virulence protein RhuM family. There are currently no experimental data for members of this group or their homologs. However, these proteins are implicated in virulence/pathogenicity because RhuM is encoded in the SPI-3 pathogenicity island in Salmonella typhimurium.	1.88527e-158
NZ_CP046176.1\|WP_007837575.1\|1542684_1544106_+\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|373012	pfam14322, SusD-like_3, Starch-binding associating with outer membrane. SusD is a secreted polysaccharide-binding protein with an N-terminal lipid moiety that allows it to associate with the outer membrane. SusD probably mediates xyloglucan-binding prior to xyloglucan transport in the periplasm for degradation. This domain is found N-terminal to pfam07980.	2.70954e-44

>NZ_CP046176.1|WP_005848349.1|1533922_1534255_+|CRISPR-associated-endonuclease-Cas2
MDRFSEYRIMWVLVLFDLPTETKKDKKAYTDFRKNLQKDGFTMFQFSIYVRHCASSENATVHINRVKSFLPEYGQVGIMCITDKQFAAIELFYGKKLQGVTTPGQQLELF
>NZ_CP046176.1|WP_007837565.1|1532990_1533923_+|type-II-CRISPR-associated-endonuclease-Cas1
MIKKTLYFGNPAYLSLRNNQLVIKLPEVEKSDSLPDIFKEQSEITKPIEDIGVVVLDHKQITITFGVLESLLENNCAVITCDSKSMPVGLMLPLYGNTTQNERFRQQLDASLPLKKQLWQQTIKAKIDNQASVLRVCVGEEMKCMRIWANEVKSGDPENLEARAAAFFWKNLFADIIGFTRDREGISPNNLLNYGYAILRAIVARALVASGLLPTLGIHHHNRYNAYCLADDVMEPYRPYVDELVFSLVKLYGANLELTKEIKSRLLVIPTLDVRINGKRSPLMVAVAQTTASLYKCFCGEIRRISYPER
>NZ_CP046176.1|WP_007837562.1|1531965_1532964_+|virulence-RhuM-family-protein
MEENKGQILLYQTVDGESRIEVTLCNNTVWLTLDQMAELFQRNKSTISRHIKNVFESGELQESSVVAFFATTASDGKIYQVAYYNLDMIISIGYRVKSYRGVQFRIWATQILKEYLIKGFVMNDELLKRAGGGNYFDELLSRIRDIRSSEKIFYRKILEIYALSIDYDPSTESTRLFFATVQNKMHFSVHGHTAAEVIYGRADAGKDFMGLTNWTGAVPKRNDIEYAKNYLTDDELDTLNRIVSLYLDFAELQAKSHTPMYMKDWIQKLDDFLRLSGKELLQHAGTISAELAKKKANLEYDEFKKRISNQLSPVEIDFIENFEKEQKKLRGK
>NZ_CP046176.1|WP_007837560.1|1527436_1531951_+|CRISPR-associated-protein-Cas2
MKNIVGLDLGTNSIGWAVVNGSVNDDGSEQLVKIQASGSRIIPMDAAMIGDFNKGNSISQTAERTRLRGVRRLSERYLLRRERLHRILDILGFLPFHFAQDLDRHGKIVKGKEPKLAWRKNEAGQFEFIFQDSFKEMLEDFKLNYPNLITDDKKVPYDWTIYYLRKKGLTSKISKEELAWILLNFNQKRGYYQLRGEEEEENKDKLVEFYALKVVAVEDSGEKKGKDIWYNVHLENGWVYRRTSNMSLDWVGKTKEFIVTTDLEKDGTPKKDKEGNVKRSFRAPKEDDWSLVKKKTEADIDQTHKTVGAYIYDTLLGNPSQKIRGRLVRTIERKYYKEELKLILEKQKEFHLELQDRALYAACIEELYPINEAHRNNVGNRDFTYLFLEDILFYQRPLKSKKSLIDNCPYEENQGLDKETGEIKSFPVKCIAKSHPLFQEFRLWQFIINLRIYRKDLAQDVDVTNELLKTEEDYVALFDWLNGKKEIDQKAFLKYPVFGLKKEIENYRWNYVQDKPYPCNETRSLMLARLEKCDISIEFLTKENEEALWHILYSVEDKNEIVKALQKFADKHDLNASFVDVFQKFPPFKKEYGSYSAKAIKKLLPLMRMGKYWSENSIDKGTRERIDKIITGEYDEKIENRVREKAIHLADVSDFKGLPLWLVCYIVYGRHSEAKEIIQWKSPADIDSYLRSFKQHSLRNPIVEQIIIETLRVVRDIWKQVGNIDEIHVELGREMKNPADKRKKMTQQMSENENTNLRIKYLLTEFLNPEYEVENVRPYSPSQQDILRIYEEGVLNSVSDLPEEISDILKKFTETDLKKRPSRSEVLRYKLWLEQKYRSPYTGEVIPLGKLFTPAYEIEHVIPQSYYFDDSFSNKVICEAEVNKLKSNLLGHEFIVKHHGEIVELPFGKKVRIFTVDEYEQFVKDNYSRTRSKMKKLLMDDIPEEFVTRQLNDSRYISKVVKSLLSNIVREKGEEEAISKNVIPCTGGVTDRLKKDWGINEVWNKIILPRFQRLNELTGTNKFTTKNVGIQEIPTMPLELQKGFNKKRIDHRHHAMDAIIIACANRNIINYLNNKSATAKAELSRYDLQKMLCDKAKTDNNGNYKWVIRKPWASFTQDTYLALENIIVSFKQNLRVINKATNRFLHYNEEGKKIFVKQGKGDNWAIRKSMHKDTVFGEVNLRRIKTVALNEAMKNPQSIVVKDFKRKLLELWNLGFDAKRIKKYFEDNRETWSDINLSKIEVYYFSKDTKDRFFATRKPLDTSFDRKKIENNITDTGIQKILLRHLELKDNNPDIAFSPDGIDEMNRNIIQLNNGKYHQPIIKIRWYEQADKFAVGQTGNKSSKFVEAAKGTNLFFAVYESNILDKKTNTIIKKRNYATIPLNVAIERQKQGLPVAPEDENGNDPIFVLSPNDLVYLPTDDELANGIIAQPLDRGRIYKMVSSSGEQCFFIKHIVANVLVDKFEFSPLNKMERALTGEMIKMICIPIKVDRLGNVLESSSSYKK
>NZ_CP046176.1|WP_007837558.1|1525653_1527252_+|ClC-family-H(+)/Cl(-)-exchange-transporter
MKLEKWKNKWKKWSNLRKWQIWKLKLIDARLYFVSIFVGLLTGLVAVPYHYLLWYFFDVRKTFFTAHYPWYWHVLLFFILWGILIFVASLVKRMPLIAGGGIPQTRAANNGRIRYEHPFKELVAKFCGGVLALSAGLSLGREGPSVQIGSYIGTLISRWGHILKGERKQLLAAGAGAGLSAAFAAPLSSSLLVIESIERFDAPKTAITTLLAGVVAGGVASWMFPTTPYHLISAVVPGLSFIRQAELYIIFAALMAVIAKFYSLIVPFFQERIPAMKLSIPVKMLYLLTIAYAISLTETNLTGGGEQFLMMQGMNGTHDIRWLTIMMLIHFVFTLFSLSSGLPGGSFIPTLVTGGLLGQIFGLVLVQRGWIGYENVSYMMLIGMVAFLVAVVRTPLTAIVLITEITGHFEVFYPSIVVGGLTYYFTELLQIKPYNVLLYDRMFRSHNPESSEEAGARYHLFVEIMDGSYFDGKEVDTLALPNHCIIRSIHRNRKNLLPQGQTLVPGDQVEIEMDAQDIEKLYEPLVSMANIY
>NZ_CP046176.1|WP_007842555.1|1525291_1525621_+|MarR-family-transcriptional-regulator
MRELFKALSELETRLMEQYGVSLNEAMALCCIGGDTLTASVISENTGLSASHTSKVIRSIEEKELIVRNLGDKDKRQMHFTLSDKGHECLEALKANEIEIPELLKPLFK
>NZ_CP046176.1|WP_007837553.1|1522756_1525258_+|FAD-dependent-oxidoreductase
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFVQTPEAFGKRFNIDVRTRSEVIAIHSAEKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPLPGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFIGLEMAENLQEAGAEVAVVEMANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVVFKSGERLPADMVLLSIGVRPNTSLATEAGLEIGEMRGIKVNDYLQTSNEHIYAVGDAIEFRHPLTDRPWLNYLAGPANRQARIVADNMVFGNKVTYEGAVGTSIAKVFDMTVAASGLPAKRLKQAGIDYLSATIHSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVDKRIDEFSQVIKHNGAVYDLMALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFALGALKGAVNIPLDDMRERMEEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVKNLIGGLKLYKAATAPLPEPEEFSNSGSSSSDSSKVDHSEHSKDSAGAYTIASSVIPSMKAIKVDACGISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAWCQTTGNRFVSVNSGAGKYQVIVEKNTPQSSSSEVCREDKGKTFILFSDDLDKVLATFVLANGAAATGKKVTIFFTFWGLNAIKKLDKPVVKKDIWGKMFGMMLPSSSLKLKLSKMNMGGMGARMMRYIMNKKNIDSLESLRAQAIQNGVEFIACQMSMDVMGVKREELLDHVTIGGVATYMNRAEQANVNLFI
>NZ_CP046176.1|WP_007837552.1|1521164_1522520_-|MATE-family-efflux-transporter
MLSKIDLTQGGITGTLLRFTLPMIIGSLLQQCYNIADTLIVGQCIGSGALAAVGSAYTLMVFLISILLGLSMGSGTVFSLQYGAGRTDSLRRNIYVSALLIGTVTLILNIAAFVWIHPILRLLQIPKDIYGMMYDYLWIIFWGIGFTFIYNFYAALLRAIGDAVTPLWFLAVSVVLNIGLDLFFILQLDWGIKGAAIATVAAQGVSALGIMGYAYVKYPELRLHRNDLHFDRHCLKEITSFSALTCVQQSVMNLGILMVQGLVNSFGTVVMAAFAAAIKIDSFAYMPVQEFGNAFSTFIAQNFGARKEERIRKGVKSALITTVLFSLVISILVFLFAKLLMLIFVRPHETEILNIGISYLRIEGAFYCGIGILFLLYGYYRAIRMPGMSVVLTVVSLGTRVALSYWLAGIPAIGVIGIWWSIPIGWFIADVIGIIYYKQLKKETAKEVPAP
>NZ_CP046176.1|WP_007837551.1|1519339_1521202_+|SLC13-family-permease
MLITIIILVLSAVFFVNGKIRSDLVALCALVALLIFQILTPDEALSGFSNSVVIMMVGLFVVGGAIFQTGLAKMISSHILKLAGKSELKLFLLVMLVTSAIGAFVSNTGTVALMLPIVVSLAVSANMNPSRLLMPLAFASSMGGMMTLIGTPPNLVIQNALTSAGFPPLSFFSFFPVGIICVAVGTLVLLPLSKWFLSKRGKNGDDNVHSGKSLKQLVKEYGLSSNLFRLRVVGDSRLHGKTIIELDIRRKYGLNILEVRRGDMSQHRFLKTITQKLADPGTVLQKEDILYVTGDFEKIKLFAEDYLLEMLDEHTTEEAKNSANSLDFYDIGIAEIVLMPSSNLINQTIKGAGFRDKFNVNVLGIRRKKEYLLQDLGNERIHSGDVLLVQGTWNNIARLSKEDADWVVLGQPLAEAAKVTLDYKAPVAAVIMVLMVAMMVFDFIPVAPVTAVMIAGILMVLTGCFRNVEAAYKTINWESIVLIAAMLPMSLALEKTGASEYISNSLVSELGTYGPLALMAGIYFTTSLMTMFISNTATAVLLAPIAMQSATQIGVSPVPFLFAVTLGASMCFASPFSTPPNALVMPAGQYTFMDYVKVGLPLQIIMGIVMVLVLPLLFPF
>NZ_CP046176.1|WP_007837550.1|1518743_1519151_-|hotdog-fold-thioesterase
MMEEITCKPDYSNSMAEHLGIRFLPPTENAVHAEMPVDHRTSQPFGMLNGGASLALAEIVAGHGSMSLCREGEYACGVQVSGNHLSAVPVGGKVFATGKLIHRGRSSHIWNIDITTPQGELVSTVRVVNFILKKK
>NZ_CP046176.1|WP_005848347.1|1535577_1536159_-|hypothetical-protein
MNSKTNHLLLPFSIFGVSLLGLVLLNNEPRRVTPPYIKESREDSIKRVKRYKEELRRDSIFFAKVDSIKLLRDSLRNQRIYTYILKTTITPENVIVTARKSGYQQVTLDTHYTKPQLYYLVFTSTKQMSIEEASAYADRNPDKVTKLSQQQYDQRFGNQSSEYDFYLDNLDSYYDDPENLDENPDEIFDFLLD
>NZ_CP046176.1|WP_005848345.1|1536223_1536409_-|KTSC-domain-containing-protein
MDREEYLELVKMNTGIEITSVESSNIEGIGYNVKKHHLWVSFKNNKVYRYDKVLKSNSKDY
>NZ_CP046176.1|WP_007837572.1|1536824_1537415_+|epoxyqueuosine-reductase-QueH
MKKKFQLEVPGGADKVLLHTCCAPCSSAIIECLMQHGVTPVIYYCNPNIYPLEEYIIRKDECTRYAQSLGLEIIDADYDHDAWRCRMAGMEQEPERGGRCLRCFKMRLQETARYAHEHGFPVITTTLASSRWKSLEQIEEAGRYATAPYPDVTYWEQNWRKGGLSERRIAIIKEYNFYNQQYCGCEFSMRKEEKEE
>NZ_CP046176.1|WP_007837573.1|1537411_1539229_+|helix-turn-helix-domain-containing-protein
MTGMRMLKLWVVVMLLGLLPVVSEAQEEINNAINVQLEYLKKYPKDKEALRKVSFLYLNKADYDQAIFYGRQLFEMGYNERDYNGAVIYSHICLGQAHMMKGNVKEAYSHLGQARLIGESNKNDSALCSVYNGLGLYASNVQKDYYRSLTYFFKGVEAARRCHYDRLYSILLSNIAGIYYLKNDSTGLKYALECYELGHERKDPYLIYSGSTNTAYMYYLKSDYNTALKYIQEAEFTMVQNDFYDQSNVYNLYGYILHKLNKDDEALGFFRKALDLKEQGNISSVMNSYLGYAEILMEHHQYDRAVWMLKAGIELSYQQANAIYRSDLLQALSRCYEEDGMLVEALKYHKLYQLETDSLYNAEKERAVGEIRAKYDMERQENEIKQNRLELLEKENKMQLLIAGFICIFIAASLLYYLYYRKNKLYLTIVKQNQDAIRREQQLQNKIDEQFAEIGRQSALLQEYLTDSTKTSLPQPEKYASSSLTDEKKQDLFLRLETLLREEKVFTDNLLTKEKVAEMLGTNRTYLSQIINEQTKQTFTQFVNGFRTKEAVRLLSDPDNQTPLKAISAELGFNSMTTFYSQFQAATGMTPAQYRNKVQELHKNR
>NZ_CP046176.1|WP_032936679.1|1539421_1542673_+|SusC/RagA-family-TonB-linked-outer-membrane-protein
MKHSDYHGKLLRLAMVFVALFLCGTMAYAQTDRMISGIVVDENGDPLPAAHIRQVSQTKGEELAAVITDMNGHFRLTLLRTAKEIEISYLGYESKKVRLTSANSYRIVLEPASELLDEVVVTGYQTISRERATGSFAKVDSKKLETQRLSSVSSLMEGRIAGYSDGKIRGVTSMNGLTTPLYVIDGFPVEKTISDGLGNWVENVPDLNIEDIENITVLKDAAATSIYGARAANGVVVITTKKAGKNQLNVSFSATLTVRPYNFYTGHLAGTADMIEMEKEWAAMNPNLQGEGASQYAQNLLDNASMYSCLGVQAILKHHTGAISEAQMEQTLHELASQGFRYYDDVKKYGKRNPFSQQYNLNIGRGTEKNTFNASLSYRNNREEDKYTDSESFGLNLQNTTRLTSWLSLDLGTYLNYGDGTTQSYNLTSPGYNYVPYSSLLNGDGSYYTNTAADRYSKSQQEIISSYGLYSMDITPLDELGRNLSKSKNFSNRTFARLNFKFTDWLRYTASFQYEVGEYKTSQLQDKESYAVRNKVNTFATDASGSGQATYNLPYGNIYTTGTNSIRAYNFRQQLDFNKTFAEKHDVTALFGMEVRENKTEYNNRKYYNYDPALLTYDLIDERVLSNTYTGVLGNYVSFNKNDISNIYELVNRFVSFYGNAAYTYDGKYMVTGSIRWDRTNLFATGSKYQKKPIWSVGAGWNLDKESFFKVSFINMMKLRFSYGIGGNIAKNSAPYMTAYYNNNTHVGGIQGTISNRPNPDLRWEKTTTANIGVDFSMFRNRLNGSIEYYNKSGVDLLANTNGVPTEGFGFSTYTMNNGKMRNRGFELTLSGDVIMGKDWNWNVGGVLGYNKNKVTYVNVKAPAIFLQFDYPAAYPRVGVPYNAIYGYLWAGLDSKGQPQVYDSEGNIHVSSSPQKVEDAVYLGTSVPVYSGAVNTNLRYKNWELAAQLLFEGGHKMRNTNIAYPGLGVTSKDVSKRWRQPGDEAYTDVPRYVPSESKDYNSYSSDLYSKASIHVLDADNWRLKNLSVTYHVPASVCQKFYVKNARIMLGMENVFTLAKSRDVKWMLGGYSKPNYLCNVNLNF
>NZ_CP046176.1|WP_007837575.1|1542684_1544106_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKILFMIMTVLGWINLTSCNDYLDIVPKGNKIPTTLADFEALLRDEYTIGYIPVTNSLYLLNDKFVGQSSLTSVTLTSANYLWNETADRIVLNNQDEGTYYRSYMAISTCNLLLEHVPVATEATDSERNEVMAYAKVIRAMSYYILANYYADTYVSATAGTKLSVPLITSADINAPHKQVTIQEIYDFMIKDVKEAIEQGLPEQSRTVIHPNLGAAYAFLARVYLQMANYEEALKYADMALEQNDNLYDWISYYNSHKEAITKEDSYPSLPSATGYDYVENYYFRCGEGNPNYATSELNIPVERAESFEEGDARFLSRWKLRTVNQDTYYQGLAKGYFNGAGLTTCEVYLIKAECLARQVTGNDFSAAMDVLNKVRKTRILPEIYQPLQASTLTEAIDLIRRTKDNELIFTIVPFADARRFNAEGTFARALSKTWEGQTYTLTPASHLWIMPFPAGAVQNPGNGTITQNVSK
>NZ_CP046176.1|WP_007837576.1|1544124_1545306_+|AhpC/TSA-family-protein
MKLMYLLATSAVVLVMMASCTRQSVTGYTLTAAIDGIPDGSHVQLFPVSHGHEKPVADTTVVDGKFIFKGVADEPLAVRLMVKDAYGSMPLMLENGSISVEGKVTSENLNGTVNYNFSQVSVTGSPLTDKYVKLLSTRDALDSIYVTNNEKFKDIRAAYGKARVAKDKILMDSVVATEAYKASAVADSLFFATVDATYYKLVMDNKDSYWGPLMMISLFSYLTEEQKPWYDALSEEAKHSRYGKMVKESVAPDSQIGSKVPVFTAKSQDGKSVTLTDLCQGKKYVLIDFWASWCNPCRKEIPNLKKLYTQYADRGFQIVSISIDKKEAEWTKALKEEQLQWPNFLDTGGIADIYKVKFVPTMYLIDAQGVMVGENLRGEALANKLAELFGEIE
>NZ_CP046176.1|WP_007837577.1|1545869_1547159_+|porin
MKTIFKSMSCLMLGAMIVTPMFAQQKDLYPELEGPGPVVIISKDKNGKEELINVFEETQRPHFHDPRAPRFLLTDQQGKFALGIGGYLKTTMEYDFNGIVDDVDFIPALIPQPGSTAVRNQFQMDASTSTIFLKLVGRTKHLGNFIVYTAGNFRGSGKTFELQNAYLSFLGFTMGYDTGLFMDLAAAPPTIDFQGPDGMTFYRATQLRYEANLIKGLKVGVGVEMPSVDGTPAKDVRIGKQRMPDIPAYVQYSWAKASHIRVGGILRSMTYEDQVNNKAKSLTGWGIQASGTARLGNFQLYGQYTYGKGIAQYLNDISNLNVDIVPLADESGRMQVLPMKGWYVGLQYNFSKRVFASATYSQSRLFTEDCYAHFNETQYKKGQYLVANVFWNISHNLQVGVEYLHGWRENFNDVNREANRINLSAQYNF
>NZ_CP046176.1|WP_007837578.1|1547201_1548038_+|deoxyribonuclease-IV
MKKIGAHVSVSGGVEMAPVNALGIGADAFALFTKNQRQWVAKPLSVESITLFKENCEKEGFDIRYILPHDSYLINLGHPDREGMEKSRAAFLDEMRRCELLGLKMLNFHPGSHLNKISIEKCLDRIAESVNMTLDKTTGVTAVIENTAGQGSNVGNEFWHLRYIIDKVEDKSRVGVCLDTCHTYTAGYDIANEYDWVFTEFDEVVGGNYLCAIHLNDSKKPLGSRVDRHDSIGKGLIGIDFFRRFMQDSRFNDMPVILETPDDTIWRDEIKMLRSFEL
>NZ_CP046176.1|WP_007837579.1|1548361_1549726_-|TrpB-like-pyridoxal-phosphate-dependent-enzyme
MSTKQKRFILPEDEIPKYWYNIQADMKTKPMPPLNPKTKEALKPEDLYPIFAKELCKQELNQTDAWIEIPEAVREMYKYYRSTPLVRAYGLEKALGTPAHIYFKNESVSPIGSHKLNSALAQAYYCKEEGVTNVTTETGAGQWGAALSYAAKVFGLEAAVYQVKISYNQKPYRRSIMQTFGATVTASPSMSTRAGKDIITRNPNYQGSLGTAISEAIELAMSTPNCKYTLGSVLSHVTLHQTVIGLEAEKQMEMAGEYPDMIIGCFGGGSNFGGICFPFMRHTILNGKQTRYIAAEPASCPKLTRGKFQYDFGDEAGYTPLLPMFTLGHNFSPANIHAGGLRYHGAGVIVSQLLKDNLMEAVDIQQLESFQAGCLFAQAEGIIPAPESCHAIAAAIREANQCKESGEEKVILFNLSGHGLIDMASYDQYLAGNLMNYELKDEDIQKNLDEIKDM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046176_3	3.1\|1534411\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534411-1534439	29	MG945572	UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome	23-51	3	0.897
NZ_CP046176_3	3.5\|1534718\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534718-1534747	30	MG945572	UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome	5250-5279	4	0.867
NZ_CP046176_3	3.10\|1535103\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535103-1535131	29	MG945572	UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome	3110-3138	4	0.862
NZ_CP046176_3	3.12\|1535255\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535255-1535284	30	MW149106	Microvirus sp. isolate gila2, complete genome	5037-5066	4	0.867
NZ_CP046176_3	3.1\|1534411\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534411-1534439	29	NZ_CP046164	Vibrio sp. THAF191c plasmid pTHAF191c_c, complete sequence	247609-247637	6	0.793
NZ_CP046176_3	3.1\|1534411\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534411-1534439	29	NZ_CP046067	Vibrio sp. THAF191d plasmid pTHAF191d_c, complete sequence	392869-392897	6	0.793
NZ_CP046176_3	3.1\|1534411\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534411-1534439	29	NZ_CP045357	Vibrio sp. THAF64 plasmid pTHAF64_b, complete sequence	332550-332578	6	0.793
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP021643	Campylobacter concisus strain P2CDO4 plasmid pICON, complete sequence	8556-8585	6	0.8
NZ_CP046176_3	3.10\|1535103\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535103-1535131	29	MW149103	Microvirus sp. isolate gila14, complete genome	1371-1399	6	0.793
NZ_CP046176_3	3.13\|1535332\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535332-1535361	30	NZ_CP024609	Massilia violaceinigra strain B2 plasmid unnamed, complete sequence	10884-10913	7	0.767
NZ_CP046176_3	3.14\|1535409\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535409-1535437	29	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	1213283-1213311	7	0.759
NZ_CP046176_3	3.15\|1535485\|29\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535485-1535513	29	AP022646	Bacillus wiedmannii PL1 plasmid pBwiPL1-3 DNA, complete sequence	18265-18293	7	0.759
NZ_CP046176_3	3.3\|1534564\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534564-1534593	30	AY940168	Prochlorococcus phage P-SSM4, complete genome	19652-19681	8	0.733
NZ_CP046176_3	3.3\|1534564\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534564-1534593	30	JF974306	Cyanophage P-SS1 strain P-SS1, * SEQUENCING IN PROGRESS *, 2 unordered pieces	63902-63931	8	0.733
NZ_CP046176_3	3.3\|1534564\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534564-1534593	30	HQ634176	Cyanophage P-RSM3 genomic sequence	66552-66581	8	0.733
NZ_CP046176_3	3.5\|1534718\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534718-1534747	30	NZ_CP041127	Serratia marcescens strain WVU-005 plasmid pWVU-005-1, complete sequence	35772-35801	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_KY940428	UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence	15850-15879	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_011973	Bacillus cereus Q1 plasmid pBc239, complete sequence	146224-146253	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP053290	Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence	114652-114681	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP047086	Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence	165975-166004	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP041978	Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence	207844-207873	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	261103-261132	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	47430-47459	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	36745-36774	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP041980	Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence	190794-190823	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	46299-46328	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP040343	Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence	252616-252645	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP004877	Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence	283768-283797	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP014283	Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence	231518-231547	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	565743-565772	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP011350	Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence	353100-353129	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	275643-275672	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP044979	Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence	559706-559735	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP032614	Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence	405107-405136	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP007616	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB400, complete sequence	83602-83631	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP004860	Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB422, complete sequence	294823-294852	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	54252-54281	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP024685	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence	411697-411726	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP046512	Bacillus cereus strain JHU plasmid p1, complete sequence	418768-418797	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP045607	Bacillus cereus strain SB1 plasmid p1, complete sequence	2860-2889	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	296002-296031	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP011156	Bacillus cereus strain HN001 plasmid pRML01, complete sequence	403842-403871	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	43121-43150	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP010090	Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence	282185-282214	8	0.733
NZ_CP046176_3	3.13\|1535332\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535332-1535361	30	NC_008537	Arthrobacter sp. FB24 plasmid 1, complete sequence	89675-89704	8	0.733
NZ_CP046176_3	3.13\|1535332\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535332-1535361	30	NC_008538	Arthrobacter sp. FB24 plasmid 2, complete sequence	32979-33008	8	0.733
NZ_CP046176_3	3.13\|1535332\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1535332-1535361	30	NC_008539	Arthrobacter sp. FB24 plasmid 3, complete sequence	28760-28789	8	0.733
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_AP019699	Staphylococcus arlettae strain P2 plasmid pSASP2, complete sequence	7252-7281	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_KU882686	Staphylococcus lugdunensis strain Tlug63N-4 plasmid pT63N, complete sequence	25847-25876	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_KR230047	Staphylococcus epidermidis strain SP1 plasmid pSP01, complete sequence	68817-68846	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP016970	Staphylococcus epidermidis strain DAR1907 plasmid unnamed2, complete sequence	2417-2446	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP025033	Staphylococcus haemolyticus strain SGAir0252 plasmid pSGAir0252, complete sequence	24539-24568	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_LR735422	Staphylococcus epidermidis strain none isolate Se_BPH0697 plasmid 2	29539-29568	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_LR735438	Staphylococcus epidermidis strain none isolate Se_BPH0723 plasmid 2	10621-10650	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP014115	Staphylococcus saprophyticus strain FDAARGOS_168 plasmid unnamed2, complete sequence	3668-3697	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_LR735435	Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 2	11007-11036	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	LN866850	Staphylococcus capitis CR01 plasmid CR01, complete sequence	11979-12008	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	CP030478	Staphylococcus aureus strain ER02243.3 plasmid unnamed1, complete sequence	32755-32784	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP030247	Staphylococcus epidermidis strain CSF41498 plasmid pCSF41498_1, complete sequence	14674-14703	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_LT571450	Staphylococcus epidermidis isolate BPH0662 plasmid 2	37037-37066	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	403390-403419	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP033781	Staphylococcus epidermidis strain FDAARGOS_529 plasmid unnamed1, complete sequence	2359-2388	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP022250	Staphylococcus epidermidis strain ATCC 12228 plasmid pAMT2, complete sequence	16815-16844	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP023967	Staphylococcus capitis strain FDAARGOS_378 plasmid unnamed1, complete sequence	30478-30507	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP053958	Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1	10963-10992	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP031278	Staphylococcus hominis strain 19A plasmid unnamed1, complete sequence	30809-30838	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP054005	Staphylococcus hominis strain FDAARGOS_762 plasmid unnamed1, complete sequence	11025-11054	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP033100	Staphylococcus warneri strain SWO plasmid unnamed2, complete sequence	14784-14813	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP051648	Staphylococcus caprae strain SY333 plasmid pSY333-45, complete sequence	13593-13622	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP017465	Staphylococcus pasteuri strain JS7 plasmid pSNJS702, complete sequence	23489-23518	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_013389	Staphylococcus epidermidis plasmid SAP108A, complete sequence	14900-14929	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	KT359373	Staphylococcus haemolyticus plasmid pBNF01A, complete sequence	2712-2741	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP033731	Staphylococcus hominis strain FDAARGOS_575 plasmid unnamed1, complete sequence	19402-19431	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP053472	Staphylococcus warneri strain WB224 plasmid pWB224_2, complete sequence	10637-10666	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NC_013383	Staphylococcus epidermidis plasmid SAP110A, complete sequence	21533-21562	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_MK046688	Staphylococcus epidermidis strain 107.2cured plasmid pAQZ2, complete sequence	10998-11027	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_MK046687	Staphylococcus epidermidis strain 107.2 plasmid pAQZ1, complete sequence	11374-11403	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP032158	Staphylococcus warneri strain 22.1 plasmid pSW22.1, complete sequence	4758-4787	9	0.7
NZ_CP046176_3	3.6\|1534795\|30\|NZ_CP046176\|PILER-CR,CRISPRCasFinder	1534795-1534824	30	NZ_CP053657	Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence	318774-318803	9	0.7

1. spacer 3.1|1534411|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to MG945572 (UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome) position: , mismatch: 3, identity: 0.897

ttaaggctgctgatcattgtcaacatcgc	CRISPR spacer
ttaaggctgttgatcattgtcagcatcgt	Protospacer
*********.************.*****.

2. spacer 3.5|1534718|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to MG945572 (UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome) position: , mismatch: 4, identity: 0.867

-gcacgtaggtgcgcaaaggcaggttctatc	CRISPR spacer
agcacg-gagtgcgcaaaggcagattctatc	Protospacer
 ***** ..**************.*******

3. spacer 3.10|1535103|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to MG945572 (UNVERIFIED: Microviridae sp. isolate 3523-1602, complete genome) position: , mismatch: 4, identity: 0.862

aagcccaatcaagcaaaggaacagcgtga	CRISPR spacer
aattccaatccagcataggaacagcgtga	Protospacer
** .****** **** *************

4. spacer 3.12|1535255|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to MW149106 (Microvirus sp. isolate gila2, complete genome) position: , mismatch: 4, identity: 0.867

acaagtataccaatgaaaagatatcttttt	CRISPR spacer
caaaatataccaatgaaaagatatctttct	Protospacer
  **.***********************.*

5. spacer 3.1|1534411|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP046164 (Vibrio sp. THAF191c plasmid pTHAF191c_c, complete sequence) position: , mismatch: 6, identity: 0.793

ttaaggctgctgatcattgtcaacatcgc	CRISPR spacer
ccctggctgctggtcattgtcgacatcgc	Protospacer
..  ********.********.*******

6. spacer 3.1|1534411|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP046067 (Vibrio sp. THAF191d plasmid pTHAF191d_c, complete sequence) position: , mismatch: 6, identity: 0.793

ttaaggctgctgatcattgtcaacatcgc	CRISPR spacer
ccctggctgctggtcattgtcgacatcgc	Protospacer
..  ********.********.*******

7. spacer 3.1|1534411|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP045357 (Vibrio sp. THAF64 plasmid pTHAF64_b, complete sequence) position: , mismatch: 6, identity: 0.793

ttaaggctgctgatcattgtcaacatcgc	CRISPR spacer
ccctggctgctggtcattgtcgacatcgc	Protospacer
..  ********.********.*******

8. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP021643 (Campylobacter concisus strain P2CDO4 plasmid pICON, complete sequence) position: , mismatch: 6, identity: 0.8

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaacaaacaagaaaaaattgaactactaga	Protospacer
********** ** *********   *.**

9. spacer 3.10|1535103|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to MW149103 (Microvirus sp. isolate gila14, complete genome) position: , mismatch: 6, identity: 0.793

aagcccaatcaagcaaaggaacagcgtga	CRISPR spacer
tagaataatcaagcaaaggtacagcatga	Protospacer
 **  .************* *****.***

10. spacer 3.13|1535332|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP024609 (Massilia violaceinigra strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

gcatacgctgcttcgacgttggtgaaggca	CRISPR spacer
gcatacgccgcgtcgacgttggtcttggtg	Protospacer
********.** ***********   **..

11. spacer 3.14|1535409|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

catcagtgccgtttgcttactgcttttgg	CRISPR spacer
tacaggtgccgttttcttattgcttttga	Protospacer
.*. .********* ****.********.

12. spacer 3.15|1535485|29|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to AP022646 (Bacillus wiedmannii PL1 plasmid pBwiPL1-3 DNA, complete sequence) position: , mismatch: 7, identity: 0.759

tgaatacccatttgattgtgataaaaaat	CRISPR spacer
caaattcccatttgattgcgataaacggt	Protospacer
..*** ************.****** ..*

13. spacer 3.3|1534564|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to AY940168 (Prochlorococcus phage P-SSM4, complete genome) position: , mismatch: 8, identity: 0.733

tcatcaaaactggaatagaatatgaaaaga	CRISPR spacer
ctaagataactggaatacaatatgaaaatt	Protospacer
..*  * ********** **********

14. spacer 3.3|1534564|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to JF974306 (Cyanophage P-SS1 strain P-SS1, *** SEQUENCING IN PROGRESS ***, 2 unordered pieces) position: , mismatch: 8, identity: 0.733

tcatcaaaactggaatagaatatgaaaaga	CRISPR spacer
ctaagataactggaatacaatatgaaaatt	Protospacer
..*  * ********** **********

15. spacer 3.3|1534564|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to HQ634176 (Cyanophage P-RSM3 genomic sequence) position: , mismatch: 8, identity: 0.733

tcatcaaaactggaatagaatatgaaaaga	CRISPR spacer
ctaagataactggaatacaatatgaaaatt	Protospacer
..*  * ********** **********

16. spacer 3.5|1534718|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP041127 (Serratia marcescens strain WVU-005 plasmid pWVU-005-1, complete sequence) position: , mismatch: 8, identity: 0.733

gcacgtaggtgcgcaaaggcaggttctatc	CRISPR spacer
agctgtaggtgcgccaaggcaggttttgta	Protospacer
.  .********** **********.*.*

17. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_KY940428 (UNVERIFIED: Bacillus sp. (in: Bacteria) strain PUMK-07 plasmid pMK-07, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

18. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_011973 (Bacillus cereus Q1 plasmid pBc239, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

19. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP053290 (Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

20. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP047086 (Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

21. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP041978 (Bacillus pacificus strain NCCP 15909 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

22. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

23. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

24. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

25. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP041980 (Bacillus paranthracis strain NCCP 15910 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

26. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

27. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP040343 (Bacillus cereus strain DLOU-Weihai plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
aaaccaacaataaaaaattgaacagccctc	Protospacer
**** ******** **********  .

28. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP004877 (Bacillus thuringiensis serovar kurstaki str. HD-1 plasmid pBMB431, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

29. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP014283 (Bacillus thuringiensis strain Bt185 plasmid pBT1850636, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

30. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

31. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP011350 (Bacillus thuringiensis strain YC-10 plasmid pYC1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

32. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

33. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP044979 (Bacillus thuringiensis strain BT62 plasmid pBT62A, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

34. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP032614 (Bacillus thuringiensis strain QZL38 plasmid p.1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

35. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP007616 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB400, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

36. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP004860 (Bacillus thuringiensis serovar kurstaki str. YBT-1520 plasmid pBMB422, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

37. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

38. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP024685 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-1-490K, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

39. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP046512 (Bacillus cereus strain JHU plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

40. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP045607 (Bacillus cereus strain SB1 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

41. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

42. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP011156 (Bacillus cereus strain HN001 plasmid pRML01, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

43. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

44. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP010090 (Bacillus thuringiensis serovar galleriae strain 4G5 plasmid pBMB426, complete sequence) position: , mismatch: 8, identity: 0.733

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
cataaaacaatatcaaattgaccatatttt	Protospacer
 *  ******** ******** *****

45. spacer 3.13|1535332|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_008537 (Arthrobacter sp. FB24 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.733

gcatacgctgcttcgacgttggtgaaggca	CRISPR spacer
ggcccggctgcttcggcgttggtgaaggag	Protospacer
*  .  *********.************ .

46. spacer 3.13|1535332|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_008538 (Arthrobacter sp. FB24 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

gcatacgctgcttcgacgttggtgaaggca	CRISPR spacer
ggcccggctgcttcggcgttggtgaaggag	Protospacer
*  .  *********.************ .

47. spacer 3.13|1535332|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_008539 (Arthrobacter sp. FB24 plasmid 3, complete sequence) position: , mismatch: 8, identity: 0.733

gcatacgctgcttcgacgttggtgaaggca	CRISPR spacer
ggcccggctgcttcggcgttggtgaaggag	Protospacer
*  .  *********.************ .

48. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_AP019699 (Staphylococcus arlettae strain P2 plasmid pSASP2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

49. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_KU882686 (Staphylococcus lugdunensis strain Tlug63N-4 plasmid pT63N, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

50. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_KR230047 (Staphylococcus epidermidis strain SP1 plasmid pSP01, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

51. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP016970 (Staphylococcus epidermidis strain DAR1907 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

52. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP025033 (Staphylococcus haemolyticus strain SGAir0252 plasmid pSGAir0252, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

53. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_LR735422 (Staphylococcus epidermidis strain none isolate Se_BPH0697 plasmid 2) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

54. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_LR735438 (Staphylococcus epidermidis strain none isolate Se_BPH0723 plasmid 2) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

55. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP014115 (Staphylococcus saprophyticus strain FDAARGOS_168 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

56. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_LR735435 (Staphylococcus epidermidis strain none isolate Se_BPH0736 plasmid 2) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

57. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to LN866850 (Staphylococcus capitis CR01 plasmid CR01, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

58. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to CP030478 (Staphylococcus aureus strain ER02243.3 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

59. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP030247 (Staphylococcus epidermidis strain CSF41498 plasmid pCSF41498_1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

60. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_LT571450 (Staphylococcus epidermidis isolate BPH0662 plasmid 2) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

61. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
gaaccaacaataaaaaattgaacagccctc	Protospacer
.*** ******** **********  .

62. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP033781 (Staphylococcus epidermidis strain FDAARGOS_529 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

63. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP022250 (Staphylococcus epidermidis strain ATCC 12228 plasmid pAMT2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

64. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP023967 (Staphylococcus capitis strain FDAARGOS_378 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

65. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP053958 (Staphylococcus capitis strain FDAARGOS_753 plasmid unnamed1) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

66. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP031278 (Staphylococcus hominis strain 19A plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

67. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP054005 (Staphylococcus hominis strain FDAARGOS_762 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

68. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP033100 (Staphylococcus warneri strain SWO plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

69. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP051648 (Staphylococcus caprae strain SY333 plasmid pSY333-45, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

70. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP017465 (Staphylococcus pasteuri strain JS7 plasmid pSNJS702, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

71. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_013389 (Staphylococcus epidermidis plasmid SAP108A, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

72. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to KT359373 (Staphylococcus haemolyticus plasmid pBNF01A, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

73. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP033731 (Staphylococcus hominis strain FDAARGOS_575 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

74. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP053472 (Staphylococcus warneri strain WB224 plasmid pWB224_2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

75. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NC_013383 (Staphylococcus epidermidis plasmid SAP110A, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

76. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_MK046688 (Staphylococcus epidermidis strain 107.2cured plasmid pAQZ2, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

77. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_MK046687 (Staphylococcus epidermidis strain 107.2 plasmid pAQZ1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

78. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP032158 (Staphylococcus warneri strain 22.1 plasmid pSW22.1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
tgccaaccaataacaaattgaacaggcgtt	Protospacer
 . *** ***************** ..*

79. spacer 3.6|1534795|30|NZ_CP046176|PILER-CR,CRISPRCasFinder matches to NZ_CP053657 (Bacillus cereus strain CTMA_1571 plasmid p.1, complete sequence) position: , mismatch: 9, identity: 0.7

aaacaaacaataacaaattgaacatatgga	CRISPR spacer
gaaccaacaataaaaaattgaacagccctc	Protospacer
.*** ******** **********  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1425449 : 1431041

Streptococcus_phage(66.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007837430.1\|1425449_1426667_+	macrolide efflux MFS transporter Mef(A)	A0A1B0RXG2	Streptococcus_phage	6.0e-207	95.1
WP_007837431.1\|1426681_1427521_+	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	7.7e-113	73.4
WP_007750461.1\|1427517_1428177_+	Vat family streptogramin A O-acetyltransferase	A0A1V0SJ47	Klosneuvirus	2.6e-23	36.3
WP_007839296.1\|1428379_1429153_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.5e-11	29.4
WP_170272826.1\|1429149_1429827_+	23S ribosomal RNA methyltransferase Erm	E4ZFQ0	Streptococcus_phage	4.3e-53	50.2
WP_007664628.1\|1430300_1431041_+	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.1e-130	91.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP046176.1|WP_004291533.1|5173965_5174382_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP046176.1|WP_004291533.1|5173965_5174382_-|hypothetical-protein

5173965_5174382_-

138 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|40	0.5571428571428572	0.9855072463768116	0.9929078014184397

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046176

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information