CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP038450	Aeromonas media strain R50-22 plasmid pAeme6, complete sequence	1 crisprs	PD-DExK	2	2
NZ_CP038448	Aeromonas media strain R50-22 chromosome, complete genome	9 crisprs	cas14j,csa3,DEDDh,WYL,RT,PrimPol,cas3,TnsE_C,DinG,c2c9_V-U4	0	14
NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	4 crisprs	csf2gr7,DinG	27	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038450_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038450_1

75561-75691

Orphan

Consensus_repeat	Method
CAAACAGGACATTTAAGTTGGAAACT	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP038450_1

>merge|NZ_CP038450|1|75561-75691|PILER-CR
CATTTAAGTTGGAAACTGGCAGATCAAAGTATTCAATGAGTTAACGATACCAAATGTGACATTTAAGTTGGAAACTCAAAAGTAATACTACATCTGCTCCGTGAGCAAACAGGACATTTAAGTTGGAAAAC

>NZ_CP038450|1|1|75561-75691|PILER-CR
CATTTAAGTTGGAAACTGGCAGATCA	AAGTATTCAATGAGTTAACGATACCAAATGTGA
CATTTAAGTTGGAAACTCAAAAGTAA	TACTACATCTGCTCCGTGAGCAAACAGGA
CATTTAAGTTGGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038450.1\|WP_000376623.1\|80339_80840_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP038450.1\|WP_033943780.1\|70035_70596_+\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NZ_CP038450.1\|WP_001334766.1\|83677_84508_-\|oxacillin-hydrolyzing-class-D-beta-lactamase-OXA-1	unknown	unknown	gnl\|CDD\|225322
NZ_CP038450.1\|WP_001389365.1\|79068_79833_-\|IS6-like-element-IS6100-family-transposase	unknown	unknown	gnl\|CDD\|225853
NZ_CP038450.1\|WP_017411290.1\|76698_77916_+\|tetracycline-efflux-MFS-transporter-Tet(E)	unknown	unknown	gnl\|CDD\|340946
NZ_CP038450.1\|WP_000259031.1\|80967_81807_-\|sulfonamide-resistant-dihydropteroate-synthase-Sul1	unknown	unknown	gnl\|CDD\|184303
NZ_CP038450.1\|WP_003090697.1\|68637_68874_+\|broad-spectrum-mercury-transporter-MerE	unknown	unknown	gnl\|CDD\|184297
NZ_CP038450.1\|WP_001749986.1\|82370_82823_-\|NAD(+)--rifampin-ADP-ribosyltransferase-Arr-3	unknown	unknown	gnl\|CDD\|378815
NZ_CP038450.1\|WP_000414383.1\|65353_65788_-\|mercury-resistance-transcriptional-regulator-MerR	unknown	unknown	gnl\|CDD\|184302
NZ_CP038450.1\|WP_003090700.1\|66572_68258_+\|mercury(II)-reductase	unknown	unknown	gnl\|CDD\|184298
NZ_CP038450.1\|WP_017411289.1\|75985_76618_-\|tetracycline-resistance-transcriptional-repressor-TetR(E)	unknown	unknown	gnl\|CDD\|172294
NZ_CP038450.1\|WP_088813956.1\|73542_75354_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376240
NZ_CP038450.1\|WP_001294666.1\|65859_66210_+\|mercuric-transport-protein-MerT	unknown	unknown	gnl\|CDD\|184301
NZ_CP038450.1\|WP_003090698.1\|68275_68641_+\|mercury-resistance-co-regulator-MerD	unknown	unknown	gnl\|CDD\|184299
NZ_CP038450.1\|WP_000186237.1\|82907_83540_-\|type-B-3-chloramphenicol-O-acetyltransferase-CatB3	unknown	unknown	gnl\|CDD\|100040
NZ_CP038450.1\|WP_033991895.1\|70599_73566_+\|Tn3-family-transposase	unknown	unknown	gnl\|CDD\|376561
NZ_CP038450.1\|WP_000679427.1\|81800_82148_-\|quaternary-ammonium-compound-efflux-SMR-transporter-QacE-delta-1	unknown	unknown	gnl\|CDD\|279265
NZ_CP038450.1\|WP_010792470.1\|68870_69860_+\|DUF3330-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP038450.1\|WP_000732290.1\|66225_66501_+\|mercury-resistance-system-periplasmic-binding-protein-MerP	unknown	unknown	gnl\|CDD\|131107
NZ_CP038450.1\|WP_011191339.1\|78207_78777_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737

Protein	Function_ID	Function_description	E-value
NZ_CP038450.1\|WP_000376623.1\|80339_80840_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.40463e-13
NZ_CP038450.1\|WP_033943780.1\|70035_70596_+\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	1.74001e-52
NZ_CP038450.1\|WP_001334766.1\|83677_84508_-\|oxacillin-hydrolyzing-class-D-beta-lactamase-OXA-1	gnl\|CDD\|225322	COG2602, COG2602, Beta-lactamase class D [Defense mechanisms].	2.24494e-56
NZ_CP038450.1\|WP_001389365.1\|79068_79833_-\|IS6-like-element-IS6100-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.97603e-67
NZ_CP038450.1\|WP_017411290.1\|76698_77916_+\|tetracycline-efflux-MFS-transporter-Tet(E)	gnl\|CDD\|340946	cd17388, MFS_TetA, Tetracycline resistance protein TetA and related proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of tetracycline resistance proteins similar to Escherichia coli TetA(A), TetA(B), and TetA(E), which are metal-tetracycline/H(+) antiporters that confer resistance to tetracycline by an active tetracycline efflux, which is an energy-dependent process that decreases the accumulation of the antibiotic in cells. TetA-like tetracycline resistance proteins belongs to the Eukaryotic Solute carrier 46 (SLC46)/Bacterial Tetracycline resistance (TetA) -like (SLC46/TetA-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
NZ_CP038450.1\|WP_000259031.1\|80967_81807_-\|sulfonamide-resistant-dihydropteroate-synthase-Sul1	gnl\|CDD\|184303	PRK13753, PRK13753, dihydropteroate synthase; Provisional.	0
NZ_CP038450.1\|WP_003090697.1\|68637_68874_+\|broad-spectrum-mercury-transporter-MerE	gnl\|CDD\|184297	PRK13747, PRK13747, putative mercury resistance protein; Provisional.	1.44277e-48
NZ_CP038450.1\|WP_001749986.1\|82370_82823_-\|NAD(+)--rifampin-ADP-ribosyltransferase-Arr-3	gnl\|CDD\|378815	pfam12120, Arr-ms, Rifampin ADP-ribosyl transferase. This protein is found in bacteria. Proteins in this family are typically between 136 to 150 amino acids in length. The opportunistic pathogen Mycobacterium smegmatis is resistant to rifampin because of the presence of a chromosomally encoded rifampin ADP-ribosyltransferase (Arr-ms). Arr-ms is a small enzyme whose activity thus renders rifamycin antibiotics ineffective.	5.12598e-59
NZ_CP038450.1\|WP_000414383.1\|65353_65788_-\|mercury-resistance-transcriptional-regulator-MerR	gnl\|CDD\|184302	PRK13752, PRK13752, mercuric resistance operon transcriptional regulator MerR.	7.47027e-105
NZ_CP038450.1\|WP_003090700.1\|66572_68258_+\|mercury(II)-reductase	gnl\|CDD\|184298	PRK13748, PRK13748, putative mercuric reductase; Provisional.	0
NZ_CP038450.1\|WP_017411289.1\|75985_76618_-\|tetracycline-resistance-transcriptional-repressor-TetR(E)	gnl\|CDD\|172294	PRK13756, PRK13756, TetR family transcriptional regulator.	6.9164e-77
NZ_CP038450.1\|WP_088813956.1\|73542_75354_-\|hypothetical-protein	gnl\|CDD\|376240	pfam18821, LPD7, Large polyvalent protein-associated domain 7. This domain contains conserved aspartate and phenylalanine residues. It is widely present in polyvalent proteins and gene neighbourhoods of conjugative elements. This domain is also known as PTox1.	9.9018e-13
NZ_CP038450.1\|WP_001294666.1\|65859_66210_+\|mercuric-transport-protein-MerT	gnl\|CDD\|184301	PRK13751, PRK13751, putative mercuric transport protein; Provisional.	1.14568e-76
NZ_CP038450.1\|WP_003090698.1\|68275_68641_+\|mercury-resistance-co-regulator-MerD	gnl\|CDD\|184299	PRK13749, PRK13749, HTH-type transcriptional regulator MerD.	8.02451e-68
NZ_CP038450.1\|WP_000186237.1\|82907_83540_-\|type-B-3-chloramphenicol-O-acetyltransferase-CatB3	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	2.35596e-73
NZ_CP038450.1\|WP_033991895.1\|70599_73566_+\|Tn3-family-transposase	gnl\|CDD\|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	0
NZ_CP038450.1\|WP_000679427.1\|81800_82148_-\|quaternary-ammonium-compound-efflux-SMR-transporter-QacE-delta-1	gnl\|CDD\|279265	pfam00893, Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx.	4.88768e-29
NZ_CP038450.1\|WP_010792470.1\|68870_69860_+\|DUF3330-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	2.91402e-113
NZ_CP038450.1\|WP_000732290.1\|66225_66501_+\|mercury-resistance-system-periplasmic-binding-protein-MerP	gnl\|CDD\|131107	TIGR02052, periplasmic_mercuric_ion_binding_protein, mercuric transport protein periplasmic component. This model represents the periplasmic mercury (II) binding protein of the bacterial mercury detoxification system which passes mercuric ion to the MerT transporter for subsequent reduction to Hg(0) by the mercuric reductase MerA. MerP contains a distinctive GMTCXXC motif associated with metal binding. MerP is related to a larger family of metal binding proteins (pfam00403). [Cellular processes, Detoxification].	2.70309e-31
NZ_CP038450.1\|WP_011191339.1\|78207_78777_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	2.39618e-53

>NZ_CP038450.1|WP_088813956.1|73542_75354_-|hypothetical-protein
MDKVEENTGPVITDKFEREIDTALSNSEDNQKLGILRDDQGRFWDGQEFGDLEDAKRYEPVEALKVAVHVSRQYESELEGSHIYIRAVEQDEPSDSDGVHVVNTDQAMNWPHLEAAYKRGFGLNLDRDEALAITARSPAAALDNQEQAAAPAAALDNQEQAAAPAAALDNQEQAAAPAAALDNQEQAAAPAAALDNQEQAAAPAATLDNQEPEENAVEPFIERKIETADADVRAWLTNSRQPIGELIEEDERKAQHRPQAEGEFSSEPSQTPKGQASNSDFEATTFKPIVPEKVAKSYIEVDGKYYFGNRPDSLAFVDKGAKLQTKLSSEQVAASMVDIAEARGWTELQLSGTEDFRRAAWLEAASRGLASRGYKPKEEDLARLKKLTNDRTSNEIEPREQADVVPPAAKGKEQPTNQDKQQGQQAAQSPQMAKAAAATATADKQQPEAAAPAQEVNRLAGKLVEHGKAPYEHNPDNNGSYFVTLENADGQQSTTWGVGLEKAIEESQAEAGQHVELENLGRKPVQVEKQIKDEKGNVTGTKTVNSYRNEWAVKAEAIRDSSRDAKELVKEHPDLINEITAVKLAGELAEFGKNRTLRFSGHP
>NZ_CP038450.1|WP_033991895.1|70599_73566_+|Tn3-family-transposase
MPRRLILSATERGTLLALPESQDDLIRYYTFNDSDLSLIRQRRGDANRLGFAVQLCLLRYPGYALGTDSELPEPVILWVAKQIQADPTSWAKYGERDVTRREHALELRTYLQLAPFGLSDFRALVRELTELAQQTDKSLLLAGQALESLRQKRRILPALSVIDRACSEAIARANRRVYRALVEPLTDSHRAKLDELLKLKAGSSITWLTWLRQAPLKPNSRHMLEHIERLKTFQLVDLPEVLGRHIHQNRLLKLAREGGQMTPKDLGKFEPQRRYATLAAVVLESTATVIDELVDLHDRILVKLFSGAKHKHQQQFQKQGKAINDKVRLYSKIGQALLEAKEAGSDPYAAIEAVIPWDEFTESVSEAELLARPEGFDHLHLVGENFATLRRYTPALLEVLELRAAPAAQGVLAAVQTLREMNADNLRKVPADAPTAFIKPRWKPLVITPEGLDRRFYEICALSELKNALRSGDIWVKGSRQFRDFDDYLLLAEKFAALKREQALPLAINPNSDQYLEERLQLLDEQLATVARLAKDNELPDAILTESGLKITPLDAAVPDRAQALIDQTSQLLPRIKITELLMDVDDWTGFSRHFTHLKDGAEAKDRTLLLSAILGDAINLGLTKMAESSPGLTYAKLSWLQAWHIRDETYSAALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTGHVNPKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTDTAGFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAHWDDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVELRRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGKP
>NZ_CP038450.1|WP_033943780.1|70035_70596_+|recombinase-family-protein
MQGHRIGYVRVSSFDQNPERQLEQTKVSKVFTDKASGKDTQRPQLEALLSFVREGDTVVVHSMDRLARNLDDLRRLVQKLTQRGVRIEFLKEGLVFTGEDSPMANLMLSVMGAFAEFERALIRERQREGITLAKQRGAYRGRKKALSDEQAATLRQRATAGEPKAQLAREFNISRETLYQYLRTDD
>NZ_CP038450.1|WP_010792470.1|68870_69860_+|DUF3330-domain-containing-protein
MSASQPIEWTVAQLAQAVERGQLELHYQPIVDLRSEQIVGAEALLRWRHPTLGLLPPGQFLPVIESSGLMPEIGAWVLGAACRQMRDWRVLAWQPFRLAVNVAASQVGPDFDKWVKGVLADAGLPAAYLEIELTESVAFGDPAIFPALEALRQIGVRFAADDFGTGYSCLQHLKCCPISTLKIDQSFVAGLANDHRDQTIVRTVIQLAHGLGMEVVAEGVETSASLDLLRQADCDTGQGFLFAKPMPAAAFAVFVSQWRGATMNANDPTATSCCVCCKEIPLDAAFTPEGAEYVEHFCGLECYQRFQARAKTGSETDADPNACDSSLSD
>NZ_CP038450.1|WP_003090697.1|68637_68874_+|broad-spectrum-mercury-transporter-MerE
MNSPERLPTETHKPFTGYLWGALAVLTCPCHLPILAIVLAGTTAGAFIGEHWGIAALTLTGLFVLSVTRLLRAFRGRS
>NZ_CP038450.1|WP_003090698.1|68275_68641_+|mercury-resistance-co-regulator-MerD
MNAYTVSRLALEAGVSVHIVRDYLLRGLLRPVACTTGGYGLFDDAALQRLCFVRAAFEAGIGLDALARLCRALDAADCDETAAQLAVLSQFVERRREALADLEVQLAAMPTAPAQQAESLP
>NZ_CP038450.1|WP_003090700.1|66572_68258_+|mercury(II)-reductase
MTHLKITGMTCDSCAAHVKEALEKVPGVQSAIVSYAKGAAQLALDPGTAPDALTAAVAGLGYKAMLADAPPTDNRTGLFDKVRGWMGAADKGSGGERPLQVAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDGGMPPTPPTILRERLLAQQQARVEELRHAKYEGILDGNSAITVLHGEARFKDDQSLIVSLNEGGERVVMFDRCLVATGASPAMPPIPGLKESPYWTSTEALVSDTIPERLAVIGSSVVALELAQAFARLGSQVTILARSTLFFREDPAIGEAVTAAFRAEGIKVLEHTQASQVAHVDGEFVLTTGQGEVRADKLLVATGRTPNTRSLALEAAGVAVNAQGAIVIDKGMRTSSPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAAINLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSGRLIGVQVVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG
>NZ_CP038450.1|WP_000732290.1|66225_66501_+|mercury-resistance-system-periplasmic-binding-protein-MerP
MKKLFASLAIAAVVAPVWAATQTVTLSVPGMTCSACPITVKKAISKVEGVSKVNVTFETREAVVTFDDAKTSVQKLTKATEDAGYPSSVKK
>NZ_CP038450.1|WP_001294666.1|65859_66210_+|mercuric-transport-protein-MerT
MSEPQNGRGALFTGGLAAILASACCLGPLVLIALGFSGAWIGNLTVLEPYRPIFIGAALVALFFAWRRIYRPAQACKPGDVCAIPQVRATYKLIFWVVAALVLVALGFPYVMPFFY
>NZ_CP038450.1|WP_000414383.1|65353_65788_-|mercury-resistance-transcriptional-regulator-MerR
MEKNLENLTIGVFAKAAGVNVETIRFYQRKGLLPEPDKPYGSIRRYGEADVTRVRFVKSAQRLGFSLDEIAELLRLDDGTHCEEASSLAEHKLQDVREKMTDLARMETVLSELVFACHARQGNVSCPLIASLQGEKEPRGADAV
>NZ_CP038450.1|WP_017411289.1|75985_76618_-|tetracycline-resistance-transcriptional-repressor-TetR(E)
MARLSLDDVISMALTLLDREGLEGLTTRKLAQSLKIEQPTLYWHVRNKQTLMNMLSEAILVKHHTRSVPLPTESWQQFLQENALSFRKALLVHRDGARLHIGTSPTPPQFEQAEAQLRCLCDAGFSVEEALFILQSISHFTLGAVLEEQATNPTEYNTVMDAVPPLLQEAFNVQTRTTAETAFHFGLKSLIVGFSAQLDEKYMSIQGNNK
>NZ_CP038450.1|WP_017411290.1|76698_77916_+|tetracycline-efflux-MFS-transporter-Tet(E)
MNRTVMMALVIIFLDAMGIGIIMPVLPALLREFVGKANVAENYGVLLALYAMMQVIFAPLLGRWSDRIGRRPVLLLSLLGATLDYALMATASVVWVLYLGRLIAGITGATGAVAASTIADVTPEESRTHWFGMMGACFGGGMIAGPVIGGFAGQLSVQAPFMFAAAINGLAFLVSLFILHETHNANQVSDEIKNETINETTSSIREMISPLSGLLVVFFIIQLIGQIPATLWVLFGEERFVWDGVMVGVSLAVFGLTHALFQGLAAGFIAKHLGDQKAIVVGILADGCGLLLLAVITQSWMVWPVVLLLACGGITLPALQGIISVRVGQVAQGQLQGLLTSLTHLTGVIGPLIFAFLYSATHESWNGWVWIVGCGLYVVALTILRFFYPGRAAHPKNQSNSQPFL
>NZ_CP038450.1|WP_011191339.1|78207_78777_-|recombinase-family-protein
MLIGYARVSRDKQETALQLDALDKAGCQRVYVEKLSGASTERPELERCLDTLREGDTLIVWHLDRLGRSIKDLIEIVSSLKRQGIGFRSLTQSDIDTTTANGALVFHVFAALAEYERARLQERTRAGLEAARARGRRGGRPLAMSDEDARKARAMLSDVEITKAEVAKHFGVSRPTLNAALARLSPSDT
>NZ_CP038450.1|WP_001389365.1|79068_79833_-|IS6-like-element-IS6100-family-transposase
MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDHTTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTIDFYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETAHRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQPGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA
>NZ_CP038450.1|WP_000376623.1|80339_80840_-|GNAT-family-N-acetyltransferase
MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARIDRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHAGRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAERLELEI
>NZ_CP038450.1|WP_000259031.1|80967_81807_-|sulfonamide-resistant-dihydropteroate-synthase-Sul1
MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDVGPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLNDIQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSALRRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGATVGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGLDHA
>NZ_CP038450.1|WP_000679427.1|81800_82148_-|quaternary-ammonium-compound-efflux-SMR-transporter-QacE-delta-1
MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAFYFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLARSPSWKSLRRPTPW
>NZ_CP038450.1|WP_001749986.1|82370_82823_-|NAD(+)--rifampin-ADP-ribosyltransferase-Arr-3
MVKDWIPISHDNYKQVQGPFYHGTKANLAIGDLLTTGFISHFEDGRILKHIYFSALMEPAVWGAELAMSLSGLEGRGYIYIVEPTGPFEDDPNLTNKRFPGNPTQSYRTCEPLRIVGVVEDWEGHPVELIRGMLDSLEDLKRRGLHVIED
>NZ_CP038450.1|WP_000186237.1|82907_83540_-|type-B-3-chloramphenicol-O-acetyltransferase-CatB3
MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCARYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSALDAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVEPYAIVGGNPAKKIKKRFTDEEISLLLEMEWWNWSLEKIKAAMPMLCSSNIVGLHKYWLEFAV
>NZ_CP038450.1|WP_001334766.1|83677_84508_-|oxacillin-hydrolyzing-class-D-beta-lactamase-OXA-1
MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCFLLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGMEIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLTEAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGAGFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Identity
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NZ_KT033469	Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence	41059-41091	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	MF495478	Aeromonas salmonicida plasmid pS121-1b, complete sequence	75548-75580	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NZ_CP034301	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-2, complete sequence	87656-87688	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NZ_CP022170	Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence	77998-78030	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NC_016852	Aeromonas hydrophila plasmid pAHH01, complete sequence	2909-2941	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	MN865127	Vibrio alginolyticus strain C1579 plasmid pC1579, complete sequence	171654-171686	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NC_009349	Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence	2988-3020	1.0
NZ_CP038450_1	1.1\|75587\|33\|NZ_CP038450\|PILER-CR	75587-75619	33	NZ_CP038450	Aeromonas media strain R50-22 plasmid pAeme6, complete sequence	75578-75610	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NZ_KT033469	Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence	41004-41032	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	MF495478	Aeromonas salmonicida plasmid pS121-1b, complete sequence	75493-75521	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NZ_CP034301	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-2, complete sequence	87601-87629	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NZ_CP022170	Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence	77943-77971	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NC_016852	Aeromonas hydrophila plasmid pAHH01, complete sequence	2968-2996	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	MN865127	Vibrio alginolyticus strain C1579 plasmid pC1579, complete sequence	171713-171741	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NC_009349	Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence	3047-3075	1.0
NZ_CP038450_1	1.2\|75646\|29\|NZ_CP038450\|PILER-CR	75646-75674	29	NZ_CP038450	Aeromonas media strain R50-22 plasmid pAeme6, complete sequence	75637-75665	1.0

1. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NZ_KT033469 (Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

2. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to MF495478 (Aeromonas salmonicida plasmid pS121-1b, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

3. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NZ_CP034301 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-2, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

4. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NZ_CP022170 (Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

5. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NC_016852 (Aeromonas hydrophila plasmid pAHH01, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

6. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to MN865127 (Vibrio alginolyticus strain C1579 plasmid pC1579, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

7. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NC_009349 (Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

8. spacer 1.1|75587|33|NZ_CP038450|PILER-CR matches to NZ_CP038450 (Aeromonas media strain R50-22 plasmid pAeme6, complete sequence) position: , mismatch: 0, identity: 1.0

ggcagatcaaagtattcaatgagttaacgatac	CRISPR spacer
ggcagatcaaagtattcaatgagttaacgatac	Protospacer
*********************************

9. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NZ_KT033469 (Aeromonas salmonicida subsp. salmonicida strain 01-B522 plasmid pAsa4b, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

10. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to MF495478 (Aeromonas salmonicida plasmid pS121-1b, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

11. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NZ_CP034301 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-2, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

12. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NZ_CP022170 (Aeromonas salmonicida strain S121 plasmid pS121-1a, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

13. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NC_016852 (Aeromonas hydrophila plasmid pAHH01, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

14. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to MN865127 (Vibrio alginolyticus strain C1579 plasmid pC1579, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

15. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NC_009349 (Aeromonas salmonicida subsp. salmonicida A449 plasmid 4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

16. spacer 1.2|75646|29|NZ_CP038450|PILER-CR matches to NZ_CP038450 (Aeromonas media strain R50-22 plasmid pAeme6, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagtaatactacatctgctccgtgag	CRISPR spacer
caaaagtaatactacatctgctccgtgag	Protospacer
*****************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5052 : 60839

Stx2-converting_phage(40.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_119196704.1\|5052_6321_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.3e-60	33.7
WP_171277323.1\|6761_8735_-	hypothetical protein	NA	NA	NA	NA
WP_088813959.1\|9765_11327_-\|transposase	IS3-like element ISAs20 family transposase	NA	NA	NA	NA
WP_171277346.1\|11387_12884_+	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_157669159.1\|12888_13206_+	hypothetical protein	NA	NA	NA	NA
WP_088814002.1\|13688_14060_+	hypothetical protein	Q71TH9	Escherichia_phage	2.8e-06	36.1
WP_171277324.1\|14141_15446_-\|transposase	ISL3-like element ISSm4 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.1e-56	31.8
WP_171277325.1\|15438_18687_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_171277326.1\|18683_20012_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_100229850.1\|20008_21058_-	DUF1016 family protein	Q9JMP5	Wolbachia_phage	4.0e-34	33.1
WP_100229849.1\|21054_23085_-	SAM-dependent DNA methyltransferase	A0A220A2U5	Liberibacter_phage	8.9e-22	25.3
WP_088813997.1\|23990_24542_-	hypothetical protein	NA	NA	NA	NA
WP_088813996.1\|24653_25295_-	EAL domain-containing protein	NA	NA	NA	NA
WP_088813994.1\|25501_26242_-	hypothetical protein	NA	NA	NA	NA
WP_157669158.1\|26257_26563_-	hypothetical protein	NA	NA	NA	NA
WP_157669157.1\|26791_27025_-	hypothetical protein	NA	NA	NA	NA
WP_088813990.1\|27079_27316_-	hypothetical protein	NA	NA	NA	NA
WP_088813987.1\|27592_27811_-	hypothetical protein	NA	NA	NA	NA
WP_088813986.1\|27825_28086_-	hypothetical protein	NA	NA	NA	NA
WP_088813983.1\|28326_28566_-	hypothetical protein	NA	NA	NA	NA
WP_088813981.1\|28800_29370_-	restriction endonuclease	NA	NA	NA	NA
WP_157669156.1\|29482_29737_-	hypothetical protein	NA	NA	NA	NA
WP_088813979.1\|29748_30420_-	DUF4400 domain-containing protein	NA	NA	NA	NA
WP_088813978.1\|30419_32564_-	type IV conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_157669155.1\|32665_33202_-	integrating conjugative element protein	NA	NA	NA	NA
WP_157669154.1\|33216_33657_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_088813975.1\|33821_34691_-	hypothetical protein	NA	NA	NA	NA
WP_088813974.1\|34959_36330_-	hypothetical protein	NA	NA	NA	NA
WP_157669153.1\|36326_36833_-	hypothetical protein	NA	NA	NA	NA
WP_088813971.1\|38195_39038_-	TIGR03761 family integrating conjugative element protein	NA	NA	NA	NA
WP_157669151.1\|39062_39653_-	hypothetical protein	NA	NA	NA	NA
WP_088813969.1\|40032_40872_-	hypothetical protein	NA	NA	NA	NA
WP_157669150.1\|40924_42946_-	TraI domain-containing protein	NA	NA	NA	NA
WP_157669149.1\|42849_43398_-	hypothetical protein	NA	NA	NA	NA
WP_171277327.1\|43652_45035_+	hypothetical protein	NA	NA	NA	NA
WP_171277328.1\|45156_46707_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.7e-243	80.8
WP_171277329.1\|46737_47085_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	3.2e-57	90.4
WP_171277330.1\|47081_47483_-\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	3.1e-11	38.6
WP_088813965.1\|47994_48708_-	hypothetical protein	NA	NA	NA	NA
WP_157669147.1\|48714_49623_-	hypothetical protein	NA	NA	NA	NA
WP_171277331.1\|50107_50500_-	hypothetical protein	NA	NA	NA	NA
WP_171277332.1\|50621_51182_-	hypothetical protein	NA	NA	NA	NA
WP_032432545.1\|51433_54463_-\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_010465829.1\|54446_55049_-	recombinase family protein	A0A0C4UR34	Shigella_phage	1.6e-40	50.3
WP_000182276.1\|55240_55597_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_001172026.1\|55598_55934_+	XRE family transcriptional regulator	NA	NA	NA	NA
WP_000741275.1\|55948_56284_+	hypothetical protein	NA	NA	NA	NA
WP_000091614.1\|56307_56634_+	hypothetical protein	NA	NA	NA	NA
WP_001054412.1\|56630_57011_+	hypothetical protein	NA	NA	NA	NA
WP_171277333.1\|57265_58381_+	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_088813953.1\|58479_58782_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_041205730.1\|58781_59147_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_171277334.1\|59195_60839_+\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	6.9e-57	31.7

DBSCAN-SWA_2

70599 : 122742

Salmonella_phage(22.22%)

transposase,integrase

attL 93921:93935|attR 129456:129470

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033991895.1\|70599_73566_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	98.8
WP_088813956.1\|73542_75354_-	hypothetical protein	NA	NA	NA	NA
WP_017411289.1\|75985_76618_-	tetracycline resistance transcriptional repressor TetR(E)	NA	NA	NA	NA
WP_017411290.1\|76698_77916_+	tetracycline efflux MFS transporter Tet(E)	NA	NA	NA	NA
WP_011191339.1\|78207_78777_-	recombinase family protein	E5FFF9	Burkholderia_phage	1.4e-41	51.6
WP_001389365.1\|79068_79833_-\|transposase	IS6-like element IS6100 family transposase	A0A077SL39	Escherichia_phage	4.3e-86	65.7
WP_000376623.1\|80339_80840_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000259031.1\|80967_81807_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
WP_000679427.1\|81800_82148_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
WP_001749986.1\|82370_82823_-	NAD(+)--rifampin ADP-ribosyltransferase Arr-3	NA	NA	NA	NA
WP_000186237.1\|82907_83540_-	type B-3 chloramphenicol O-acetyltransferase CatB3	A0A2R8FE91	Brazilian_cedratvirus	4.1e-26	41.2
WP_001334766.1\|83677_84508_-	oxacillin-hydrolyzing class D beta-lactamase OXA-1	NA	NA	NA	NA
WP_063840321.1\|84638_85193_-	fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5	NA	NA	NA	NA
WP_000845048.1\|85484_86498_+\|integrase	class 1 integron integrase IntI1	A0A1P8DJJ6	Virus_Rctr41k	1.0e-71	45.5
WP_001138014.1\|87096_90063_+\|transposase	Tn3-like element TnAs1 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	100.0
WP_065285146.1\|92644_94015_-\|transposase	IS1182 family transposase	NA	NA	NA	NA
93921:93935	attL	NA	NA	NA	NA
WP_088813950.1\|94141_94699_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_065285147.1\|94878_96042_+	MexC family multidrug efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_088813949.1\|96057_99192_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_003152694.1\|99196_100630_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_088813948.1\|101074_102028_+	DUF4113 domain-containing protein	F1C5A5	Cronobacter_phage	5.7e-88	53.1
WP_088813947.1\|103140_103416_-	hypothetical protein	NA	NA	NA	NA
WP_157669145.1\|103616_103823_-	hypothetical protein	NA	NA	NA	NA
WP_171277335.1\|104660_105482_-	hypothetical protein	NA	NA	NA	NA
WP_088813945.1\|105700_106627_-	hypothetical protein	NA	NA	NA	NA
WP_088813944.1\|107912_108185_-	hypothetical protein	NA	NA	NA	NA
WP_088813943.1\|108171_108402_-	hypothetical protein	NA	NA	NA	NA
WP_088813942.1\|108653_108830_-	hypothetical protein	NA	NA	NA	NA
WP_088813941.1\|109333_110020_-	hypothetical protein	NA	NA	NA	NA
WP_171277336.1\|110119_110467_-	hypothetical protein	NA	NA	NA	NA
WP_171277337.1\|110815_110968_+	hypothetical protein	NA	NA	NA	NA
WP_088813939.1\|111236_111602_-	hypothetical protein	NA	NA	NA	NA
WP_157669143.1\|112974_113859_-	hypothetical protein	NA	NA	NA	NA
WP_088814086.1\|115084_115453_+	hypothetical protein	NA	NA	NA	NA
WP_088813938.1\|115735_116071_-	hypothetical protein	NA	NA	NA	NA
WP_088813937.1\|116951_117404_+	hypothetical protein	NA	NA	NA	NA
WP_157669142.1\|117476_118595_-\|integrase	tyrosine-type recombinase/integrase	A0A0K0N6I5	Gordonia_phage	1.5e-07	32.8
WP_088813935.1\|118591_119707_-	DNA-binding protein	NA	NA	NA	NA
WP_088813934.1\|120059_120485_+	hypothetical protein	NA	NA	NA	NA
WP_088813933.1\|120617_121331_-	hypothetical protein	NA	NA	NA	NA
WP_001809438.1\|121710_122742_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
129456:129470	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP038448

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038448_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_1

95070-95165

TypeV

Consensus_repeat	Method
CGCTGGCGGGTATCAGCCCTTGAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_1

>merge|NZ_CP038448|1|95070-95165|CRISPRCasFinder
CGCTGGCGGGTATCAGCCCTTGAGCGCCAGCCACAATGGTGAAGCCCTCCAAGGCCAGGCGGGCTTTGGGCGCTGGCGGGGTATCAGCCCTTGAGC

>NZ_CP038448|1|1|95070-95165|CRISPRCasFinder
CGCTGGCGGGTATCAGCCCTTGAGC	GCCAGCCACAATGGTGAAGCCCTCCAAGGCCAGGCGGGCTTTGGGC
GCTGGCGGGGTATCAGCCCTTGAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_171269910.1\|102623_103067_-\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP038448.1\|WP_005326902.1\|104199_104529_-\|DUF3634-family-protein	unknown	unknown	gnl\|CDD\|315081
NZ_CP038448.1\|WP_041205051.1\|93607_94945_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP038448.1\|WP_010676219.1\|85626_86724_-\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP038448.1\|WP_171269454.1\|92453_93557_+\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NZ_CP038448.1\|WP_005327195.1\|98124_98454_-\|cytochrome-o-ubiquinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|182568
NZ_CP038448.1\|WP_005332142.1\|88446_89763_+\|HipA-domain-containing-protein	unknown	unknown	gnl\|CDD\|341494
NZ_CP038448.1\|WP_081805658.1\|90821_91310_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|377396
NZ_CP038448.1\|WP_041205386.1\|99069_101046_-\|cytochrome-o-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|131890
NZ_CP038448.1\|WP_042648130.1\|95578_96940_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341025
NZ_CP038448.1\|WP_171269912.1\|104631_105600_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|239116
NZ_CP038448.1\|WP_005332143.1\|89861_90104_+\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NZ_CP038448.1\|WP_005327189.1\|98453_99065_-\|cytochrome-o-ubiquinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|182628
NZ_CP038448.1\|WP_171269911.1\|103187_104096_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP038448.1\|WP_081805657.1\|101049_102123_-\|cytochrome-o-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|182518
NZ_CP038448.1\|WP_041205391.1\|90382_90811_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|377396
NZ_CP038448.1\|WP_171270003.1\|85102_85639_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236344
NZ_CP038448.1\|WP_005327197.1\|97220_98111_-\|protoheme-IX-farnesyltransferase	unknown	unknown	gnl\|CDD\|184001
NZ_CP038448.1\|WP_005332127.1\|91410_92304_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP038448.1\|WP_171269909.1\|86786_87854_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236344

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_171269910.1\|102623_103067_-\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.356e-20
NZ_CP038448.1\|WP_005326902.1\|104199_104529_-\|DUF3634-family-protein	gnl\|CDD\|315081	pfam12321, DUF3634, Protein of unknown function (DUF3634). This family of proteins is found in bacteria. Proteins in this family are typically between 103 and 114 amino acids in length.	2.71735e-21
NZ_CP038448.1\|WP_041205051.1\|93607_94945_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.77276e-31
NZ_CP038448.1\|WP_010676219.1\|85626_86724_-\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	2.77602e-25
NZ_CP038448.1\|WP_171269454.1\|92453_93557_+\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	1.44382e-26
NZ_CP038448.1\|WP_005327195.1\|98124_98454_-\|cytochrome-o-ubiquinol-oxidase-subunit-IV	gnl\|CDD\|182568	PRK10582, PRK10582, cytochrome o ubiquinol oxidase subunit IV; Provisional.	1.72324e-54
NZ_CP038448.1\|WP_005332142.1\|88446_89763_+\|HipA-domain-containing-protein	gnl\|CDD\|341494	cd17809, HipA_So_like, type II toxin-antitoxin sytem toxin HipA from Shewanella oneidensis and similar proteins. This family contains type II toxin-antitoxin (TA) system HipA family toxins similar to Shewanella oneidensis HipA, a serine/threonine-protein kinase that phosphorylates Glu-tRNA-ligase (GltX), preventing it from being charged, leading to an increase in uncharged tRNA(Glu). This induces amino acid starvation and the stringent response via RelA/SpoT and increased (p)ppGpp levels, which inhibits replication, transcription, translation and cell wall synthesis, reducing growth and leading to persistence and multidrug resistance. HipA is the toxin component of the HipA-HipB TA module that is a major factor in persistence and bioflim formation; its toxic effect is neutralized by its cognate antitoxin HipB. HipA, with HipB, acts as a a corepressor for transcription of the hipBA promoter. In the Shewanella oneidensis HipAB:DNA promoter complex, HipB forms a dimer that binds the duplex operator DNA, with each HipB monomer interacting with separate HipA monomers. The HipAB component of the complex is composed of two HipA and two HipB subunits.	4.36737e-159
NZ_CP038448.1\|WP_081805658.1\|90821_91310_-\|DMT-family-transporter	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	5.46678e-21
NZ_CP038448.1\|WP_041205386.1\|99069_101046_-\|cytochrome-o-ubiquinol-oxidase-subunit-I	gnl\|CDD\|131890	TIGR02843, Cytochrome_bo3_ubiquinol_oxidase_subunit_1, cytochrome o ubiquinol oxidase, subunit I. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	0
NZ_CP038448.1\|WP_042648130.1\|95578_96940_-\|MFS-transporter	gnl\|CDD\|341025	cd17472, MFS_YajR_like, Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli inner membrane transport protein YajR and some uncharacterized multidrug-efflux transporters. YajR is a putative proton-driven major facilitator superfamily (MFS) transporter found in many gram-negative bacteria. Unlike most MFS transporters, YajR contains a C-terminal, cytosolic YAM domain, which may play an essential role for the proper functioning of the transporter. YajR-like transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.98615e-157
NZ_CP038448.1\|WP_171269912.1\|104631_105600_-\|nucleoside-hydrolase	gnl\|CDD\|239116	cd02650, nuc_hydro_CaPnhB, NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. .	8.34966e-137
NZ_CP038448.1\|WP_005332143.1\|89861_90104_+\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.11664e-44
NZ_CP038448.1\|WP_005327189.1\|98453_99065_-\|cytochrome-o-ubiquinol-oxidase-subunit-III	gnl\|CDD\|182628	PRK10663, PRK10663, cytochrome o ubiquinol oxidase subunit III; Provisional.	1.25062e-128
NZ_CP038448.1\|WP_171269911.1\|103187_104096_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.20129e-78
NZ_CP038448.1\|WP_081805657.1\|101049_102123_-\|cytochrome-o-ubiquinol-oxidase-subunit-II	gnl\|CDD\|182518	PRK10525, PRK10525, cytochrome o ubiquinol oxidase subunit II; Provisional.	0
NZ_CP038448.1\|WP_041205391.1\|90382_90811_-\|DMT-family-transporter	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	2.46704e-13
NZ_CP038448.1\|WP_171270003.1\|85102_85639_-\|hypothetical-protein	gnl\|CDD\|236344	PRK08869, PRK08869, polar flagellin E.	2.40928e-29
NZ_CP038448.1\|WP_005327197.1\|97220_98111_-\|protoheme-IX-farnesyltransferase	gnl\|CDD\|184001	PRK13362, PRK13362, protoheme IX farnesyltransferase; Provisional.	5.93149e-139
NZ_CP038448.1\|WP_005332127.1\|91410_92304_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.40185e-95
NZ_CP038448.1\|WP_171269909.1\|86786_87854_-\|hypothetical-protein	gnl\|CDD\|236344	PRK08869, PRK08869, polar flagellin E.	1.76622e-53

>NZ_CP038448.1|WP_041205051.1|93607_94945_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNGPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP038448.1|WP_171269454.1|92453_93557_+|YdcF-family-protein
MKKTAIALTLTSLLTLPLVVSSDAWAAPVRSLQKEQNYEQFISKRQVVDQLLADATRIFHSPARVSDAGFTAKMPSNMEQVTTLLLEAHQLEPYRTDLLISAANAQIYNGNVERAIALFEQALTAAPDDLDINTYLATWLRFKGDQTKSDGYVKRVVELNAGRAADLQRLFATVDRVVATPLKERQGRGEKKGRRAIVTLGYALNPDGSMNDILLGRLETTRALAQADPAALVILTGGVPQNRQTEGKLMADWLAKKGIDRSRIIEENYATSTVENALYSGYALARHEIEYATLVSSASHVRRGQTLLEIACWQSGPATIRIDSVAYPDKPLSALAKASPEELLGIYRDALRTYGLWSYRSAPLVER
>NZ_CP038448.1|WP_005332127.1|91410_92304_+|LysR-family-transcriptional-regulator
MNQDAFALLPAFVAVVESGSFSGAARQLGLSKSVLSKKVSQLEQALGCQLIYRTTRSLTLTEAGERYFETVRHAVRLASDGEDAIGALQSAPRGLLRVTVPMVYGRRHIAPLVPEFLALHPEVQLQLEMSDAQQDLVAEGFDVAVRIGELEDSSLVARRLAPCLSTLCAAPAYLAQAGTPHTPADLERHNCLFYSLFRGGTQWRLHGPEGEVAITPRGNFEVNNSDAIHTALLAGLGIGNMPDFIVARDLAAGRLVPVLPGHALPEHGVWCVYPRRRHLPAKVEAWLAFLQERLGLR
>NZ_CP038448.1|WP_081805658.1|90821_91310_-|DMT-family-transporter
MIPPLVDRGPGRPALGQTLGQTLGALAAFAAGLLLALMIAQNGALARATDPWLGSWLAHGVGTLVAALLWWLSPRPPTPEAAPPWAWLGGLPGALTVVLAALCLNSSLGMAGTLALLLLGQLLFGALCDGLGWLGLARRRPSGKDALAALLVMAGALLIVLG
>NZ_CP038448.1|WP_041205391.1|90382_90811_-|DMT-family-transporter
MTILILLGLLNGVAVSLSRTLNGRLASARGAMTASLANHLLGFGLLGALLILKGAPWERLAGLDPWLLLGGVLGALFVAISSWAIGRVGALACALLIVTGQLAGGALLDALAGRLAASDLLGILLVLAGAALQRWQAGKPRS
>NZ_CP038448.1|WP_005332143.1|89861_90104_+|DUF3297-family-protein
MSDNKPALPDRLAANPRSPHHVAECFQHEIGIRVNGKERTNVEEYCISEGWVKIPSPKAKDRYGNAMLITVKGTVEAFYA
>NZ_CP038448.1|WP_005332142.1|88446_89763_+|HipA-domain-containing-protein
MMSGSERHRLELRLGNQLIGHLEYDSQRDTFQLGYTPAWQARGFPISPPLALDGSASSAQIRAYLGNLLPENRGLEHLIEALSVSRSNLFALIHGIGRDVSGAVTFTLPAEPDIPTHFRPITPEELMLRLDQPELWPLEVWDGRPRLSVAGVQAKLNLLRLEGALGFGEGEICSTHLLKFEHHPHLVINEFVTMRLAALLGMPVAQVELHRVGQGDKSHRGLLVERFDRRLDEDGLRVRRRHMIDACQGLGFPVTRKYERNFGDGRDVAHIREGVSLPRLFSLSVLCVNPAQARLDMLQWLLFNLCVNNHDAHGKNYSFFVSKAGLMPTPWYDLVNVGLYPEFNQHLAMAIGDEFAPEAVNAWQLLEMAEACDLPKRLLQQTLHKVASDILHQLDAAIALVETDNPAELAYLARYRDDVERRCHHFQEQATLLPELQR
>NZ_CP038448.1|WP_171269909.1|86786_87854_-|hypothetical-protein
MLLSIRTNITAIAAQRNLSSLMGSFDSSLKRLSSGLRINSAADDAAGLQISNRLTSEINGSNGAIRNINDAISVINVADGAMDESMNLMQRMRTLALQAGSGINSTDDRAALNMEFQQMRLEMDRIATKTTFAGQSLLAGTYEGVFSIGAYAGQNMVITDMNAQTKNLGEMVWQSRSPTSSKPGAHSIDGLQLGAQPITLNGVTFDTNYPTLEAFVADINSTSFPNNQSPIEAVQHPFSVRSSIDLSTLPSYIDIEGQTVDLTTGIDMTGWDPVNPTSENSWLMATVVHQINMAAQSAGLGFSVSGSYNNNPANNQLTIHSSQGNSLTLANGSIHPPQPPQPAPPALPQGGIALC
>NZ_CP038448.1|WP_010676219.1|85626_86724_-|ISAs1-family-transposase
MTLIEHLTLVEETRSEINRKHNLVDVMFLVISAIMSGAEGWNDIETYGDSKIDWLRQHRPFANGIPRRHTVARILRCIVIDTLLEALLCWVNEQRTHQGKPIIAFDGKVLRGSFRGNAKDALQLVTAYDTENGLVLSQKATPNKKGEIETVKDMLDILELKGAVVTLDALHCQRETLEKISEKKAHVVVQVKNNQPKLYQAVQSQFQSLFDAQKEKIVVEHKESGHGRQEERYVFQLKAKLPPELTEKWPTIRSIIAVERHRSANGKGTVDTSYYVSSLSPKHKLLGHYIRQHWRIENSQHYILDVVFNEDASRIAMEDAVENMALFRRFVLNIVKQSNCGARSQRNKLKRAGWNDDYRAQLFFG
>NZ_CP038448.1|WP_171270003.1|85102_85639_-|hypothetical-protein
MLWLKYQQSVLPPWALPIPPISANPSLSALLTDVSSTTYIGQLELSSSGTRYSNIDMEGNTLGSLGFFLQDKQKYTVDNIDVLSESNASRAIRTLDAGMKQIGVQRSQIGAQANSLEARGRSLSTSHENLSAARARIRDADIASESARMVRVQIMQQASASILSQANSRPKLALSLLQ
>NZ_CP038448.1|WP_042648130.1|95578_96940_-|MFS-transporter
MNDFTMTRGERRATWALGSVFSLRMLGMFMVLPVLTTYGMSLAGASEALIGLAIGIYGMTQALFQIPFGLLSDRIGRKPLIVGGLLMFAAGSVIAALSDSIWGVIVGRALQGSGAISAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVTGPLITQAVGLSGLFWLIALLALAAIAMVIWVVPTPAAHLQNRESAMVRGGFRTVLTNPRLLKLNLGILCVHTLLMSSFVALPPLLEQAGLAREQQWQAYLVTMLVAFVSVVPFIIYAEKHRQMKRVFIGCVLVMLAAELVLWQAGLQLWGLLAGLQLFFVGFNVMEALLPSLISKESPPGYKGTAMGVYSTSQFLGVAIGGSLGGLLYSLGGGPLVFGGCAVLALLWFGVSLTMAEPPYVSSLRIVLPEGVEATPALEQRIRACDGVSDVLLVREEHSLYVKVDSKRLTRSDLERLVSL
>NZ_CP038448.1|WP_005327197.1|97220_98111_-|protoheme-IX-farnesyltransferase
MMKQYLQVTKPGIIFGNLISVIGGFLLASKGSLDVPLFILTMVGVSLVVASGCVFNNYIDRDIDCIMERTKNRALVRGLIAPGVSLWYATALGVAGIALLYFAANPLAALLAVLGFLVYVGVYSLYMKRHSVYGTLVGSLSGAAPPVIGYCAVSGQFDSGALILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKHHITLYILAFMVPTLMLFLGGYAGYKYLIVATAVSVWWLGMALSGYKAAVDDSLWARKLFMFSIVTITCLSVMMSVDFQPDAAPVLVSMLP
>NZ_CP038448.1|WP_005327195.1|98124_98454_-|cytochrome-o-ubiquinol-oxidase-subunit-IV
MSHSVDNHGASHGSVKSYMTGFVLSLILTAIPFWMVMDGSASHAMVLGTVVGMAVVQIFVHLIYFLHMNTSSEERWNLVALVFTVLIIAIVVVGSLWIMYNLNINMMVH
>NZ_CP038448.1|WP_005327189.1|98453_99065_-|cytochrome-o-ubiquinol-oxidase-subunit-III
MATDVLHHTHGAHEDGHHDAGATKVFGFWIYLMSDCILFATLFATYAVLVNGTAGGPTGKDIFELPFVFAETMLLLLSSITFGFGMLAMNKNKVSAVNTWLLVTFLLGAGFIAMEIYEFHHLIVNDAGPDRSGFLSAFFTLVGTHGIHVTSGLIWIIVMMVLISKKGLTERNRTRLMCLSLFWHFLDVVWICVFTVVYLMGVM
>NZ_CP038448.1|WP_041205386.1|99069_101046_-|cytochrome-o-ubiquinol-oxidase-subunit-I
MFGKLTLEAVPYHEPIIMVTIACIILGGLAIAGLITYYGKWQYLWKEWFTSVDHKRLGIMYLILGMVMLLRGFADAVMMRGQQVMASAGSEGYLNAHHYDQIFTAHGVIMIFFVAMPLVIGLMNIVVPLQIGARDVAFPFLNNLSFWFTAAAVVLINVSLGVGEFAQTGWLAYPPLSGLEFSPGVGVDYWIWSLQISGLGTLLTGVNFFATIIRMRAPGMTMMRLPVFTWTALCANILIIASFPILTVTIALLTADRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGIFSEVVATFCKKKLFGYTSLVWATVAITVLSFVVWLHHFFTMGSGANVNAFFGITTMIISIPTGVKIFNWLFTMYRGRIEFSSPMLWTVGFIITFTVGGMTGVLLSVPAANFVLHNSLFLIAHFHNVIIGGVVFGCFAGITYWFPKAFGFKLDDVWGKRAFWFWITGFFVAFMPLYVLGFMGMTRRVSQNIDPEFHGWLVVAACGAGLIAIGVLCQLIQVVVSIRDREKNRDWTGDPWGGRTLEWATSSPPPFYNFAIEPKVTGLDAFWEAKEDGSAYRQPAKYAPIHMPKNSGAGVIIAAFSVVFGFAMIWHIWWMAIAGFVGMIATWIIHSFNDDVDYYVQVDEIERIEGQHFDNINKVA
>NZ_CP038448.1|WP_081805657.1|101049_102123_-|cytochrome-o-ubiquinol-oxidase-subunit-II
MRPFEVKRGLGALLLMATAGLLSGCDMALMSPKGQVGLEQKSLILTALGLMLIVVIPVIIMTVAFARKYRASNTTAKYTPDWSHSNKIEAVVWTVPVIIVAILAVITWKTSHSLDPYKPLESDVKPIQVDVISLDWKWLFVYPELGIASVNELAFPVNTPINFRVTSDTVMNSFFIPQLGGQIYAMAGMQTKLHLIANEAGQYKGISGSYSGAGFSGMKFKAIATQDQAGFDAWVAKVKQSPKMLSTMGEFDALAKKSENHPVEYFASADPKLFVNVINKFMGGMSHGGHDAAKDGAMDHEAMKHDAAKAEPMDHKAMNHDAAKAESMDHAAMSHDEHAGHMATSMADKSVKAGSEE
>NZ_CP038448.1|WP_171269910.1|102623_103067_-|carboxymuconolactone-decarboxylase-family-protein
MSDRIQLASQVPAAVSAMMGLEAYLGGTDIPLSLKELIKLRASMLNGCAYCIEMHAEVAMKHGDSPQRLLALAAWRESPLFDERERAVLALTDEVTLIGERGLTEETYQQALALLGETLLAQCLMQVVTINAWNRIAVATRMEHKHP
>NZ_CP038448.1|WP_171269911.1|103187_104096_+|LysR-family-transcriptional-regulator
MLDRVRILAQVVESGSFSRAARALNLAPSSVTRTIDALEQQLGIPLFKRSTRQLVLTEQGEYFLARSARLLEEADQLVQSLQPLPVAPEGPLRVSVFESFGAAWLAPRLPAFLARYPGVRLEIELDNRLVDLDAENVDVAVRIGRPVDSGLHARHLLTNRTLLVASPAYLARHGEPAHPDELAHHNCLIRGHGRQRQHWYFRQGAQRHRVAVRGNLASVGGTPLLCAAQAGTGILLLSSWMVQQGIDDGTLQPLLPDWQASPYEDRHDEIHAVFRGGRFLKPQTRAFIDFLIEVMKPLQVPR
>NZ_CP038448.1|WP_005326902.1|104199_104529_-|DUF3634-family-protein
MAWLSLLVAIALIWWLMKLGRGALFEIRLQPGKVLLKRGSVPPRFLAQAKQILQQEPVRGRILGQRDGNGVRLVFSRSIPEPVAQRLRSVFPYGDYRGVTSPPDGRNAR
>NZ_CP038448.1|WP_171269912.1|104631_105600_-|nucleoside-hydrolase
MTHKIILDTDPGIDDAMAILFAEAHPAIDLLAITTVFGNATIENGTRNALWLKQKYGMKAEVAQGAAAPLLREPVGPTTVVHGPSGLGDVEAGEVTLAPDPRPAWQYIVETVKASPDEITLVTIGPLTNLALALEAAPEITALVKQVVVMGGAFGVNGHRGNVTPYAEANIHDDPEAADRVFTAPWPVVIIGLDVTQQSFFSSAYLDALRDDAGEPGRFLWAVSRFYLRFYSERIGLNGCHVHDPSAIAYVIDPELFTLREGPVRVIDHGPAIGHTLQKFDGKSHPHDEWARFPAQRVGVAVRDQALLALYRETLVAWGKDC

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Crispr_ID: NZ_CP038448_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_2

484831-484991

Orphan

Consensus_repeat	Method
GTGGAGACCGAAGAGCAGCTGATGGACAAATTTGTGCTGATGCACAGGCAGTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_2

>merge|NZ_CP038448|2|484831-484991|CRISPRCasFinder
GTGGAGACCGAAGAGCAGCTGATGGACAAATTTGTGCTGATGCACAGGCAGTAAAATTTGCATCAGCGTCTGCACCTTGTGGACTGCATCCTCCGGGATCCCGCTCATGTGGAGACCGAAGAGCAGCTGATGGACAAGTTTGTGCTGATGCACAGGCAGTA

>NZ_CP038448|2|2|484831-484991|CRISPRCasFinder
GTGGAGACCGAAGAGCAGCTGATGGACAAATTTGTGCTGATGCACAGGCAGTA	AAATTTGCATCAGCGTCTGCACCTTGTGGACTGCATCCTCCGGGATCCCGCTCAT
GTGGAGACCGAAGAGCAGCTGATGGACAAGTTTGTGCTGATGCACAGGCAGTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_161506929.1\|487058_487412_+\|DsrE-family-protein	unknown	unknown	gnl\|CDD\|224470
NZ_CP038448.1\|WP_042648799.1\|486506_486899_-\|DUF1090-domain-containing-protein	unknown	unknown	gnl\|CDD\|368932
NZ_CP038448.1\|WP_161506932.1\|478543_479944_+\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NZ_CP038448.1\|WP_005326646.1\|491088_491358_-\|30S-ribosomal-protein-S15	unknown	unknown	gnl\|CDD\|180170
NZ_CP038448.1\|WP_005326662.1\|481889_482816_-\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|182294
NZ_CP038448.1\|WP_005326640.1\|492969_495666_-\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NZ_CP038448.1\|WP_005329794.1\|472816_473224_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|234795
NZ_CP038448.1\|WP_139751019.1\|473977_476329_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_171268618.1\|479943_481284_+\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NZ_CP038448.1\|WP_005326642.1\|492479_492914_-\|30S-ribosome-binding-factor-RbfA	unknown	unknown	gnl\|CDD\|234787
NZ_CP038448.1\|WP_042648795.1\|495686_497189_-\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|236410
NZ_CP038448.1\|WP_041205051.1\|485122_486460_+\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP038448.1\|WP_171268617.1\|487421_488627_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_CP038448.1\|WP_042648796.1\|491518_492478_-\|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl\|CDD\|235333
NZ_CP038448.1\|WP_005329795.1\|470779_472474_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_171268619.1\|476444_477356_-\|site-specific-tyrosine-recombinase-XerD	unknown	unknown	gnl\|CDD\|234713
NZ_CP038448.1\|WP_005326664.1\|481415_481811_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319911
NZ_CP038448.1\|WP_041205198.1\|483272_484634_+\|tRNA-5-hydroxyuridine-modification-protein-YegQ	unknown	unknown	gnl\|CDD\|237969
NZ_CP038448.1\|WP_041205197.1\|488760_490908_-\|polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|236995
NZ_CP038448.1\|WP_005326670.1\|477553_478072_+\|flavodoxin-FldB	unknown	unknown	gnl\|CDD\|183471

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_042648799.1\|486506_486899_-\|DUF1090-domain-containing-protein	gnl\|CDD\|368932	pfam06476, DUF1090, Protein of unknown function (DUF1090). This family consists of several bacterial proteins of unknown function and is known as YqjC in E. coli.	9.75072e-27
NZ_CP038448.1\|WP_161506932.1\|478543_479944_+\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	3.04935e-122
NZ_CP038448.1\|WP_005326646.1\|491088_491358_-\|30S-ribosomal-protein-S15	gnl\|CDD\|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	1.62223e-53
NZ_CP038448.1\|WP_005326662.1\|481889_482816_-\|L,D-transpeptidase-family-protein	gnl\|CDD\|182294	PRK10190, PRK10190, L,D-transpeptidase; Provisional.	1.9553e-145
NZ_CP038448.1\|WP_005326640.1\|492969_495666_-\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NZ_CP038448.1\|WP_005329794.1\|472816_473224_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|234795	PRK00567, mscL, large-conductance mechanosensitive channel protein MscL.	4.76888e-73
NZ_CP038448.1\|WP_171268618.1\|479943_481284_+\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	8.58319e-59
NZ_CP038448.1\|WP_005326642.1\|492479_492914_-\|30S-ribosome-binding-factor-RbfA	gnl\|CDD\|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	4.37598e-52
NZ_CP038448.1\|WP_042648795.1\|495686_497189_-\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|236410	PRK09202, nusA, transcription elongation factor NusA; Validated.	0
NZ_CP038448.1\|WP_041205051.1\|485122_486460_+\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.77276e-31
NZ_CP038448.1\|WP_171268617.1\|487421_488627_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.85457e-68
NZ_CP038448.1\|WP_042648796.1\|491518_492478_-\|tRNA-pseudouridine(55)-synthase-TruB	gnl\|CDD\|235333	PRK05033, truB, tRNA pseudouridine synthase B; Provisional.	0
NZ_CP038448.1\|WP_161506929.1\|487058_487412_+\|DsrE-family-protein	gnl\|CDD\|224470	COG1553, DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism].	2.21751e-42
NZ_CP038448.1\|WP_171268619.1\|476444_477356_-\|site-specific-tyrosine-recombinase-XerD	gnl\|CDD\|234713	PRK00283, xerD, tyrosine recombinase.	5.17051e-178
NZ_CP038448.1\|WP_005326664.1\|481415_481811_+\|VOC-family-protein	gnl\|CDD\|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.32843e-29
NZ_CP038448.1\|WP_041205198.1\|483272_484634_+\|tRNA-5-hydroxyuridine-modification-protein-YegQ	gnl\|CDD\|237969	PRK15452, PRK15452, putative protease; Provisional.	0
NZ_CP038448.1\|WP_041205197.1\|488760_490908_-\|polyribonucleotide-nucleotidyltransferase	gnl\|CDD\|236995	PRK11824, PRK11824, polynucleotide phosphorylase/polyadenylase; Provisional.	0
NZ_CP038448.1\|WP_005326670.1\|477553_478072_+\|flavodoxin-FldB	gnl\|CDD\|183471	PRK12359, PRK12359, flavodoxin FldB; Provisional.	8.27097e-121

>NZ_CP038448.1|WP_041205198.1|483272_484634_+|tRNA-5-hydroxyuridine-modification-protein-YegQ
MFRPELLSPAGTLKNMRYAYAYGADAVYAGQPRYSLRVRNNEFDHENLQLGINEAHALGKQFYVVANIQPHNSKLKTFIRDMRPVVDMKPDALIMSDPGLIMMMREAFPDMPIHLSVQANAVNWATVKFWHQMGLTRAILSRELSLDEIEEIRMQVPEMELEVFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNSCRWEYKVHEGKEDDVGQIVHRQEPIAVRPDNTLGLGKPSDALVLLEESNRPGEYMTAFEDEHGTYIMNSKDLRAVEHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAVAGRPFDPTLMGTLENLAHRGYTEGFLRRHNHSEYQNYDYGYSVSDTQQFVGEITGRQGDMVEVEVKNKFLVGNSLELMTPQGNVSFNLEQMQNRKGELIDTAPGNGHVVYVPVPKEIDVNYGILLRNLGDRQDTRQPHSAA
>NZ_CP038448.1|WP_005326662.1|481889_482816_-|L,D-transpeptidase-family-protein
MNPLRIAASALFCTLTLVSQQAAAVEYALPAANSRLIGENQEYVVPADNRPLEQIAADFQLGLTNIMEANPGVDPYLPTPGSKLTIPHQLILPNAPREGIVINVAEMRLYYYPKGKNVVQVLPIGIGQLGVNTPENWITKVERKRANPTWTPTENIRRRYAAQGKTLPAVWPAGPDNPMGLHALYIGNLYAIHGTNATFGIGLRVSSGCVRLRADDIKYLFDNVPVGTRVQFVNQPVKTTVEPDGGRYMEVHEPLSRTEEEFNSTASVPLPMTPATTRFIAHMDSDSNVVKQVLEQRTGMPTRLNPEA
>NZ_CP038448.1|WP_005326664.1|481415_481811_+|VOC-family-protein
MLENTKMDNTLVWADIPTRDLDRAMDFYSALLDVQVTPIQEEEMRFAMLRYDGSNAAACLGPMDKYHQPGGAGPLIYLSLGDRLQEAEQLVPRLGGRVLEPLHSIGSGHGSRVIIEDTEGNWLALYAPPAA
>NZ_CP038448.1|WP_171268618.1|479943_481284_+|TldD/PmbA-family-protein
MSTLDMNTLLTRLLDKVVDLGAEADVIANQEKAFSLKADKGELGEYKVTSSQQLGIRLIKEGRVGIAYSESLDELALDAMLQDALDASRFAKVDADQRISVAGSRITTDCAEIHQPDTTAVEEKIALALRLEADMLAQPDVTGAPYNSFFEGENRLWLANSLGSLCQHSEFSVGCYTSALVERDGRQSMHSQGQYGRHFDELDSQTLIEQIYAVAHDLLPGEAVPSGRYSVLFSTNCFASLFGCFQGALSGKWAQQGINPWRSKVGQSVASRWLTLESRAYMPGGMNIKAFDGEGAATSDLLLIGEGELKTLLHNSATARHFGVASNGSAARSARSALDVTARHLVFGTGPHSEGEVQSGDYLELVKLDGLHSGADAVSGDFSFGASGFLCRDGVRVQPVRGITVAGNFYRLLGELEAVGDTLHHKDGKGFYAPLIRFGGLNIAGK
>NZ_CP038448.1|WP_161506932.1|478543_479944_+|TldD/PmbA-family-protein
MTSFSLLAPAIARDVLDHALALGADFAELFVERKRRSQLSLLSSQIENISGGLDFGIGVRLCYGHKVLYGYTNLASREELLRIVSLLAAKDRRDPMVTATAFDFTPITDRNPVALPLSADKQLEQKIAYLHAMDAVARAESSKVSQFSGNVLGWEQEVEIFNSEGLQVADRRHYNRIMAQTIAVEGGEQSVGYEAPGALMGWEHADRIDPRELALTATRQALVKLGAAPCPSGTLPVIMESGFGGVIFHEACGHLLETTSVAKKASVFHDKMGQLIANPAVSAVDEGLQSNAWGSINVDDEGMATQHTQLIKDGVLTGFLVDRMGAIKTGHARTGSGRRESYKFAPTSRMRNTYIEPGNHSLEEMLATVEHGIYAKKMGGGSVQPGTGEFNFNVQEAYLIEHGKITRPLKSATLIGTGPQVLKEISMVGRNLALAAGMCGSVSGSVPTSVGQPALKVDNILVGGNA
>NZ_CP038448.1|WP_005326670.1|477553_478072_+|flavodoxin-FldB
MKIGLFYGSTTCYTEMAAEKIRALIGPELVDLHNIKDVPLARMQEYDILILGISTWDFGELQEDWESRWEDIKDVPLEGRIIALFGMGDQLGYGEWYQDALGLLHDQLVPKGVRLVGYWPNEGYEFDASKALIDDGRHFVGLALDDANQYDQTESRIEQWVDQILSEIHELL
>NZ_CP038448.1|WP_171268619.1|476444_477356_-|site-specific-tyrosine-recombinase-XerD
MTKPAPAVHNHPLIEPFLDALWLERGLSDNTVSSYRTDLEKFALWLDGQGGSLLLAGMDDIQHYLAWRVDKQFAASSTARFLSALRRFYQYLNREKLRSDDPTVLLEGPKLPKKLPSDLSEAEVDALLTAPLVDDPLELRDKAMLELLYATGLRVSELVGLTAEHVSLRQGLVRVVGKGNKERLVPMGEEAVHWLERYYREARTLLLGGTSSDVVFPSKQARMMTRQTFWHRIKLYAQRAGIRGELSPHTLRHAFATHLLNHGADLRVVQMLLGHADLSTTQIYTHVANERLKALHGEHHPRA
>NZ_CP038448.1|WP_139751019.1|473977_476329_+|hypothetical-protein
MKPSQHNRLLKSLTVPFGIVMLGGLSLTPAWAGIFPGLQQEACMADAYIAKGGSLAGGSLNCTAKDIEVSKVVPVNPNQECTNGQVFTFNADVTIKTNASERYDTTFYLPRTSQSPQVVQGGARNCSLVLPKASDAGENGQVAYVNLEPKLKATDFLDTCGDITKANGTDQYTLLNQPITMLCQPSPTDPNKALFTYCAAWDIQKSLSCSESTVPPGAVPATKSKCNCDSFAINVFIRPEPPTITKTVEPTSLPEPGGVFTYNLSFTNSSAASLYIASLKDEIDVGGDGSYDKSVDLWGATESVGTADGIYLLSSTCAKPAAGSTTKEVLPSATYSCEFTLHIKDRDLPNDQSPEKYVDNIVALFKDKNGGTVGDGSTCPTGFQSAGNNCSAAKMVEITNLPPAIAVEKTPSVDEVLEPGANVTYTVRVTNTAGDHDDPLTLTSLVDDKFGDLDGQGTCDLGSGVALFKGSPFECSFTEFVGGNAGDVHTNKVTAKALDNEGDEATGDDSATVNINDVASTITLQKDAVPISVLETGDSDEKRSVAYTFTFSVDAGGVDKVTFNDLDDDVFGNLTSLCQVSKKNGVTLVPAVALSGFMLNPGESASCTLSKDLQGNAGESHTNTATISGKDEDNQTVTDSDDATVMFTDEKPDISKLFALKAAGFVRISNNGVDTLTVTALTFKGIDVADGNGIPGSFTLYDEPGVSTHEGGFGPFAFCTTGGTILPGGHYDCAFVLELEPGLADLGNIDLQAINPEPLVVTLKDDELNEVKAEVEVTIQTLE
>NZ_CP038448.1|WP_005329794.1|472816_473224_+|large-conductance-mechanosensitive-channel-protein-MscL
MSLIQEFKAFAARGNVIDMAVGIIIGAAFGKIVSSFVGDVIMPPIGLILGGVDFSDLAVTLKAAEGDIPAVVIAYGKFIQTIIDFLIISFAIFMGLKAINTLKKKQEEAATPAGPTKDQELLTEIRDLLKSQQGK
>NZ_CP038448.1|WP_005329795.1|470779_472474_+|hypothetical-protein
MDTRAIPLWPRCWQHGLTALTLLLALCAPALAATAESPFELDANPQDNIDTGAVMSDDWDTPPDTGGATKFTGIIQDTAPRSIFGGGDKDILDIDKWSWSDGSVPDKDDLTHAYAAAYNENNDLLLYFGADRISNVGDAFMGFWFFKQKVTALPNGKFSGKHTAGDTLVLMNFPQANNAVPYLAVVTWDPTCSKAANNNPQPGQCAASNLRLKLQGSGANDVVCASQGGANLACALTNTGNVPVPASTLANGVGGLWSDYTPKSGTQGTFPFESFFEGGINLSQIVGGSDGCFSSFMAETRSSSSFTAALKDFVLDNFELCKVEITKVCTGGDLNETETGFTFSFEGVVTNGGFGTIYDVVVTDDNGTPADTSDDFIVASFDSIPKGGMEDYSGSFGAAGNGPTNGVSVKAASSDGGLQTITASATAACPTVQREPGISVTKACSTKVIDEGSQLVIRVDYSGQVCNTTGVGLIPPLNLSGVTVTDDPSGNVHNIGTLNAADCKDYSGSYTPSSAGSENPGSISFSDTVTATGTAPLGFGTATDMATATCPLCPTCPDCPTPGQ
>NZ_CP038448.1|WP_041205051.1|485122_486460_+|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNGPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP038448.1|WP_042648799.1|486506_486899_-|DUF1090-domain-containing-protein
MWKIAGIGLLLLAGQAYGSENVGCKARHQAVTEQLSFARAHDNAQQVAGLEQALRNIETHCTDAGLIKEQQEKVAKQKQEVEERLADLQSARVSGKPDKIAKKQAKLEASQAELLEAQRELEALQKLVKP
>NZ_CP038448.1|WP_161506929.1|487058_487412_+|DsrE-family-protein
MKQQIVIIANGAPYGTESLFNALRLGIALNEQEGIDLKLFLMSDAVSAALAGQSPAEGYNLRQMLEILLAQGTQIRLCKSCTDARGITALPLIEGIEVGTLPLLAQWTLAADKVLTF
>NZ_CP038448.1|WP_171268617.1|487421_488627_-|MFS-transporter
MSWALIRQFPPLVWIVILGTFMVRTTFFMVWPFLSILLYRDYGLSATLIGLILGATAALSTLVSFYGGWLSDKWGRRNILLFGCLVSALSVALLGLSHQVIWLAIGVIGSGLSYGLIDSPGKALMADSLAEPKARELALHLRYFLLNLGAAIGPLLGVSYGLSARQETFLLLSVSYLLLGFIFLVGFRLAACQPGHAAGPGMRAVLRVLWQDRGFLLLTMANMLLMLVYAQFESPLIQYLTRAGTPEVERLIGWLVSTNALTIVILQFPLLHLTANWSIKRRLQLGVAFFLSAQLQFALGDTAIWWHWIVAVILLSIGECILFPLLNVLVDQMAPEHLKGSYFGAASMSGLGIAIGALLGGWILANWGGSWLYGCMALLCLAILMLYGLSTRTSRPALVRA
>NZ_CP038448.1|WP_041205197.1|488760_490908_-|polyribonucleotide-nucleotidyltransferase
MNPIVKSFQYGQHTVTLETGVMARQATAAVMVSMDDTCVFVTVVGKKEADHGRDFFPLTVNYQERTYAAGRIPGGFFRREGRPSEGETLISRLIDRPIRPLFPEGFLNEVQVVATVMSVNPAVSPDIVAMIGASAALAISGIPFGGPIAAARVGYMNGQYVLNPTTTELPQSDLDLVVAGTANAVLMVESEAAILSEEVMLGAVVYGHEQMQVVINAINEFAADVGTQPWDWTPPAVNEALKAKVAELATAELGEAYRITEKAVRYAAIGAIKGRVVEQVIASGVEEDAKKIGEEFHSLESRIVRGRVVRGEPRIDGRDPEMIRALSVGTGILPRAHGSALFTRGETQAIVVATLGTERDAQNIDELSGHRADRFMLHYNFPPYCVGETGMMGSPKRREIGHGRLAKRGVAAVMPSAAEFPYVVRVVSEITESNGSSSMASVCGSSLALMDAGVPIKASVAGIAMGLVKEEEGFVVLSDILGDEDHLGDMDFKVAGTTQGITALQMDIKIEGITKEIMEIALKQARGARLHILKVMDEAIQAPRAEISDFAPRIHTIKINPEKIKDVIGKGGSVIRALTEETGTNIELDDDGTVRISAVANEAAMEAIRRIEAITAEIEVNRIYEGKVVRLADFGAFVNILPGKDGLVHISQITDARVQNVADFLKIGDVVKVKVLEVDRQGRVRLSIKEANAPTETAAPVADVAVAAVEEPAAE
>NZ_CP038448.1|WP_005326646.1|491088_491358_-|30S-ribosomal-protein-S15
MSLNAEIKASIVADNARCANDTGSPEVQVALLTAQINHLQGHFKEHSKDHHGRRGLLRMVSQRRKLLDYLKRKDVQRYAALIAKLGLRR
>NZ_CP038448.1|WP_042648796.1|491518_492478_-|tRNA-pseudouridine(55)-synthase-TruB
MSRRRRFKGRDVHGILLLDKPTGLTSNDVLQKVKRIYNAAKAGHTGALDPLATGMLPICLGEATKFSQYLLEADKRYEVTAKLGERTNTSDSDGEVVSTRPVNVAVGTLIEALDQFRGPIMQVPSMYSALKHNGRPLYEYAREGIEIEREARPITVFELKLLSFEGDEVRLEVHCSKGTYIRSLVDDLGEVLGCGAHVTQLRRTQVASYPYDRMLTLEQLECIFEQAKAESIPPREQLDPLLLPMDTAVASLPEVNMLTAVAAYVNQGQAVQVAGAPQSGQVRMTVGPEREFIGVGEIDDEGRVAPKRLVRYHDDRDEE
>NZ_CP038448.1|WP_005326642.1|492479_492914_-|30S-ribosome-binding-factor-RbfA
MAREFSRTRRVGQQIQREIALILQREVKDPRIGMVTVSDVEVSKDLNYAKIYVTFLQLENDAERIAEGLKGLTEAAGYIRSLLGSAMRLRVVPELRFYYDQTLVEGMRLSNLVTNTVREDKRRMTEAGREEDEAAPDDTTEDKA
>NZ_CP038448.1|WP_005326640.1|492969_495666_-|translation-initiation-factor-IF-2
MAEVSVKQLATDIDTPVDRLLQQFVDAGISKSKADDLVSESEKQTLLAHLKKQHGGDEITAPARMTLQRKTKSTISVQGTGGKNKEVQVEVRKTRTYVKRSALEDEQRQAEAEEKARLEAEEKARHEAENKARLDAEEKARREAEQARREAEEKARIEAQSKARQAPQPAKVAASTAQQEAEKMAKREAEELKRQQEQTALQKAEELAAKKAEEARLMAEQNGPRWAEEEAARAKESSDYHLTTNKHAQAAEDELDRKEETSRRTAAAAVKAPKKATRREDDRDSRNPRARKGKRGKVAMPNAMKHGFNKPAAVVNRDVVIGETITVAELANKMAVKGVEVIKAMMKMGAMATINQVIDQETAQLVAEEMGHKVLLRRENELEEAVLSDRDETSEAKPRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETDSGMITFLDTPGHAAFTSMRARGAKSTDIVVLVVAADDGVMPQTIEAIQHAKAAEVPIVVAVNKIDKPEADPDRVKTELARYNVMSEDWGGDSQFVHVSAKSGEGIDDLLEAILIQSEVLELKAVVDGMASGVVIESFLDKGRGPVATVLVQEGTLRQGDIVLCGLEYGRIRAMRDELGREIKEAGPSLPVEILGLSGVPSAGDEATVVRDEKKAREVALYRQGKFRDVKLARQQKAKLENMFANMTEGEVSEVNVVIKADVQGSVQAICDALVQLSTDEVKVKIVGSGVGGITETDATLAAASSAILVGFNVRADASARKVIESESLDLRYYSVIYDLIDEVKQAMSGKLAPEYRQEIIGLAEVRSVFKSPKFGAVAGCMVTEGVVKRSNRIRVLRDNVVIYEGELESLRRFKDDVNEVRNGYECGIAVKNYNDVREGDQIEVYETIEIQRTL
>NZ_CP038448.1|WP_042648795.1|495686_497189_-|transcription-termination/antitermination-protein-NusA
MNKEILLVVDAVSNEKAVPREKIFQALETALATATKKKYEGEIEVRVEIDRKTGDYDTYRRWVVVADQASMENPYGEITLEAAQIEQPDIQIGDYVEDQIDSVTFDRITTQTAKQVIVQKVREAERSQVVDQFKDKEGTIISGVVKKSNRDNVILDLGSNAEAVIFRDDMLPRETFRPGDRIRGLLYAVRPEARGSQLFVSRSSPDFLKELFRIEVPEIGEEMIEIMGAARDPGSRAKIAVKTNDRRIDPIGACIGMRGARVQAVSAELSGERADIVLYDDNPAQYVINAMAPADVASIIVDEDNHTMDIAVEAANLAQAIGRNGQNVRLASQLTGWELNVMTVEDMRAKHQAENDRILTLFTTALDIDDDFAGLLMEEGFSTLEEIAFVPVNELLAIDGLDEDMVEELRKRAKDVLTTKALAKEESFDGVEPSEELLNLNGLGRDMAYALAARGVGTLEDLAEQGIDDLADIEELTAEKAGELIMAARNICWFGEEQSE

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Crispr_ID: NZ_CP038448_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_3

1969040-1969140

Orphan

Consensus_repeat	Method
GGACGATTTAGTCTGGAGTTGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_3

>merge|NZ_CP038448|3|1969040-1969140|CRISPRCasFinder
GGACGATTTAGTCTGGAGTTGATGCCAGGTCGGTACCGATGAGAGTGTTGCGTACAGTTATCACCCTGGCCAACCCGGACGATTTGGTCTGGAGTTGATGC

>NZ_CP038448|3|3|1969040-1969140|CRISPRCasFinder
GGACGATTTAGTCTGGAGTTGATGC	CAGGTCGGTACCGATGAGAGTGTTGCGTACAGTTATCACCCTGGCCAACCC
GGACGATTTGGTCTGGAGTTGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_171269334.1\|1970156_1972730_+\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_CP038448.1\|WP_043132833.1\|1974162_1974624_+\|transcriptional-regulator-AsnC	unknown	unknown	gnl\|CDD\|183019
NZ_CP038448.1\|WP_171269335.1\|1969246_1969984_+\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|182677
NZ_CP038448.1\|WP_041206563.1\|1960963_1962448_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|236520
NZ_CP038448.1\|WP_041206565.1\|1954236_1956126_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP038448.1\|WP_043132834.1\|1973016_1974009_-\|aspartate--ammonia-ligase	unknown	unknown	gnl\|CDD\|235456
NZ_CP038448.1\|WP_161507671.1\|1975567_1976104_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227700
NZ_CP038448.1\|WP_041206561.1\|1962758_1964051_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NZ_CP038448.1\|WP_171269339.1\|1957755_1958919_+\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|185092
NZ_CP038448.1\|WP_041207111.1\|1967208_1967964_-\|outer-membrane-protein-assembly-factor-BamD	unknown	unknown	gnl\|CDD\|274513
NZ_CP038448.1\|WP_050504434.1\|1977416_1977965_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|376515
NZ_CP038448.1\|WP_171269331.1\|1976634_1977339_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180586
NZ_CP038448.1\|WP_171269340.1\|1956709_1957612_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|377694
NZ_CP038448.1\|WP_171269337.1\|1965680_1967009_+\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|181958
NZ_CP038448.1\|WP_171269333.1\|1974719_1975484_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|366132
NZ_CP038448.1\|WP_041206559.1\|1964207_1965608_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP038448.1\|WP_171269338.1\|1959425_1960952_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|236507
NZ_CP038448.1\|WP_171269332.1\|1976100_1976505_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341392
NZ_CP038448.1\|WP_106885551.1\|1978090_1978183_+\|YnhF-family-membrane-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_171269341.1\|1956180_1956693_-\|lipocalin-family-protein	unknown	unknown	gnl\|CDD\|182489

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_171269334.1\|1970156_1972730_+\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_CP038448.1\|WP_043132833.1\|1974162_1974624_+\|transcriptional-regulator-AsnC	gnl\|CDD\|183019	PRK11179, PRK11179, DNA-binding transcriptional regulator AsnC; Provisional.	5.63656e-111
NZ_CP038448.1\|WP_171269335.1\|1969246_1969984_+\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|182677	PRK10723, PRK10723, polyphenol oxidase.	2.23702e-120
NZ_CP038448.1\|WP_041206563.1\|1960963_1962448_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta	gnl\|CDD\|236520	PRK09444, pntB, Re/Si-specific NAD(P)(+) transhydrogenase subunit beta.	0
NZ_CP038448.1\|WP_041206565.1\|1954236_1956126_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	5.25781e-71
NZ_CP038448.1\|WP_043132834.1\|1973016_1974009_-\|aspartate--ammonia-ligase	gnl\|CDD\|235456	PRK05425, PRK05425, asparagine synthetase AsnA; Provisional.	0
NZ_CP038448.1\|WP_161507671.1\|1975567_1976104_+\|hypothetical-protein	gnl\|CDD\|227700	COG5413, COG5413, Uncharacterized integral membrane protein [Function unknown].	4.30823e-29
NZ_CP038448.1\|WP_041206561.1\|1962758_1964051_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	3.88542e-137
NZ_CP038448.1\|WP_171269339.1\|1957755_1958919_+\|alcohol-dehydrogenase	gnl\|CDD\|185092	PRK15138, PRK15138, alcohol dehydrogenase.	0
NZ_CP038448.1\|WP_041207111.1\|1967208_1967964_-\|outer-membrane-protein-assembly-factor-BamD	gnl\|CDD\|274513	TIGR03302, OM_YfiO, outer membrane assembly lipoprotein YfiO. Members of this protein family include YfiO, a near-essential protein of the outer membrane, part of a complex involved in protein insertion into the bacterial outer membrane. Many proteins in this family are annotated as ComL, based on the involvement of this protein in natural transformation with exogenous DNA in Neisseria gonorrhoeae. This protein family shows sequence similarity to, but is distinct from, the tol-pal system protein YbgF (TIGR02795). [Protein fate, Protein and peptide secretion and trafficking].	2.30836e-98
NZ_CP038448.1\|WP_050504434.1\|1977416_1977965_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|376515	pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).	1.33555e-21
NZ_CP038448.1\|WP_171269331.1\|1976634_1977339_+\|SDR-family-oxidoreductase	gnl\|CDD\|180586	PRK06483, PRK06483, dihydromonapterin reductase; Provisional.	1.38114e-71
NZ_CP038448.1\|WP_171269340.1\|1956709_1957612_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|377694	pfam06719, AraC_N, AraC-type transcriptional regulator N-terminus. This family represents the N-terminus of bacterial ARAC-type transcriptional regulators. In E. coli, these regulate the L-arabinose operon through sensing the presence of arabinose, and when the sugar is present, transmitting this information from the arabinose-binding domains to the protein's DNA-binding domains. This family might represent the N-terminal arm of the protein, which binds to the C-terminal DNA binding domains to hold them in a state where the protein prefers to loop and remain non-activating. All family members contain the pfam00165 domain.	1.10527e-49
NZ_CP038448.1\|WP_171269337.1\|1965680_1967009_+\|CoA-disulfide-reductase	gnl\|CDD\|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	0
NZ_CP038448.1\|WP_171269333.1\|1974719_1975484_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|366132	pfam00497, SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.	9.73627e-24
NZ_CP038448.1\|WP_041206559.1\|1964207_1965608_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP038448.1\|WP_171269338.1\|1959425_1960952_+\|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha	gnl\|CDD\|236507	PRK09424, pntA, Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha.	0
NZ_CP038448.1\|WP_171269332.1\|1976100_1976505_-\|CBS-domain-containing-protein	gnl\|CDD\|341392	cd04629, CBS_pair_bac, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.11684e-53
NZ_CP038448.1\|WP_171269341.1\|1956180_1956693_-\|lipocalin-family-protein	gnl\|CDD\|182489	PRK10477, PRK10477, outer membrane lipoprotein Blc; Provisional.	1.60292e-82

>NZ_CP038448.1|WP_041207111.1|1967208_1967964_-|outer-membrane-protein-assembly-factor-BamD
MGKKSRLLMSLALVATLITGCSSTKPKVPDEPPEVLYQKARLKLDTGNYLNAIELLEALDSRYPFGAYSSQVQLDLIYAYYKQDDTAQAIANIDRFIRLNPAHKNIDYVFYMRGLTNMAADYNFFQDFLGIDRDDKDPSYARQAFQDFKTLLQNYPNSQYAADARARMVGLKTRLARYDLGVAEYYVKRDALIAAANRAKLVVETYPDTVETEKALEIMVNAYDTLKMPTLARHAREVLAKNYPDNRLGRG
>NZ_CP038448.1|WP_171269337.1|1965680_1967009_+|CoA-disulfide-reductase
MRIVIIGGEAAGMSAAAKARRLARDAEIVVYEASEVISFGACGLPYFVGDDFQEPGYMAEFTPEQFAAKGIEVKIGHRVLSLDAAAQTLRVEHKGDSFTDRYDRLMIATGAREQMPPIPGLQQQGVFGLRRMSDGLALKTAVQDPCSKKAVVIGSGFIGLEVVEALVHQGKEVRLIELADRVIPDAFDSEITQHIETELREQGVCLHLGERVQALLGEGRVSGVRTDQGEYEADIVVVCTGVRPNTEFLADTGIARLGNGAIKVDRQGRSSLANVWAAGDCASVWHSVKKQQVYVPLATIANKLGRMVGENLAGAEQEFPGTLGSAALKVLGLEAGRTGLSEQEAKAMGIDYRTVVIKDKCHTNYCPGQSDIHVKLVYEAGSKRLLGGQILGRKGAVHRIDALAVAITMGVTTEQLGMLDFAYAPPFSRTWDVLNVAGNVAK
>NZ_CP038448.1|WP_041206559.1|1964207_1965608_+|L-cystine-transporter
MTLSVIGNLAILVMLLLFLYRLQQTHVSFTRRVFSGLGLGVLFGWALQLLYGVGSEVLVQTGDYLDLVGSGYVKLLQMIIIPLIMVSIIGAILKLSGGTALGKISALTIGVLIFTTMIAAGAGILMSNLFGLSAEGLTAGAAETARGAALQTSLGSVESMSLAKMVLEFIPANPFLDMTGSRKTSTIAVVIFAIFIGLSATGIARKQPEIFASFERFMGVAHAIVMRMVTLVLRLTPYGVLALMAKVVSGSNYADIINLLNFVLASYGAIAIMFLVHLLLVSLVGINPLRFLKKIMPVLAFAFTSRTSAGSIPMNVQTQTRALGIPAGIANFAASFGATIGQNGCAGIYPAMLAVMIAPTVGVNPLDPGFIMTLIAIITVSSFGVAGVGGGATFAALIVLSALDFPVALAGLLISIEPLIDMGRTALNVSGSITAGTLTSRLMGQTDMAVFNGDAEVSLDGEESAV
>NZ_CP038448.1|WP_041206561.1|1962758_1964051_+|serine-dehydratase-subunit-alpha-family-protein
MKAQWTDFITLLKREVVPALGCTEPMSVALAAANCRKLLGQDPTRISVWVSGNLFKNGMGVGVPGTGMIGLPVAAAVGITGGNPDAGLEVLKTLTPQQVDAAKALLPIIQVDVKDVPDVLYAEVLAEADGHSARVVICTDHTRIVLLEKDGEVLMEQDSAPGVQIQPAKSDKPAMTLREIVAFALEVPLTEIAFIREAASMNQALADEGLQGYGLRIGKILTEQVERKLLSDDLMTLAMRLSSAASDARMDGAMLPAMSNSGSGNQGIAATMPVVAAARFLKADDEQLARALVMSHLVAIYIKAYQNKLSALCAASTAAMGSGAAITWLLGGQFEQISHCINNMIGDVSGIICDGAGSACSMKVSTSTSAAVKSSLMAINNLHVPQSEGIVSDDVDQTIANLGRLSKQGMLDTDIEIINIMRAKQQGKAG
>NZ_CP038448.1|WP_041206563.1|1960963_1962448_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-beta
MSQGLVTASYIVAAVLFILSLAGLSKQETAKHGNLFGIAGMAIALLATVFNPETSGVHWIILAMVIGGAIGVRLALKVEMTEMPELVAVLHSFVGMAAVLVGFNSFIDLHPSAPAEVVVSVGSNLDATLAAARAAFEQAASVAQVEHLSGAMLNIHLVEVFLGVFIGAVTFTGSVVAFGKLRGLISSKPLQLPHRHKLNLLAVVVSLALMIHFVNAGGSTFALLLMTLIAFAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVVGALVGSSGAILSYIMCKAMNRSFISVIAGGFGSDGVASTADQEMGEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAEITHKLRERGVKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINEDFSDTDVVLVIGANDTVNPAAMEDPGSPIAGMPVLEVWKAQNVIGFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVEAILKAL
>NZ_CP038448.1|WP_171269338.1|1959425_1960952_+|Re/Si-specific-NAD(P)(+)-transhydrogenase-subunit-alpha
MQIGIPRESLAGETRVAATPATVEQLKKLGFEVAIEAGAGQLASFDDAAFEAAGASVVPSVWQADLIFKVNAPTDAEIAQIKDGATLVSFIWPAQNPELVKKLSERNINVMAMDMVPRISRAQSLDALSSMANIGGYRAVVEAAHQFGRFFTGQITAAGKVPPAKVLVIGAGVAGLAAIGTAGSLGAIVRAFDTRLEVAEQIESMGGEFLKLDFGGEDGASSDGYAKVMSDEFIKAEMELFAQQAKEVDIIITTALIPGRPAPKLITREMVDSMKPGSVIVDLAAATGGNCEYTKPTELFVTPNGVKVIGYTDLPGRLPAQSSQLYGTNLVNLMKLMCKEKDGNVAIDFEDVVQRNMTVIQAGEVTFPPPAIAVSAAPQKPAAAKPAAKKEEAKPSNKKFVFGALGIAAFGWVAAVAPAAFLSHFTVFILACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGSTLVTVLAFIAVLIASINIFGGFTVTQRMLKMFRKD
>NZ_CP038448.1|WP_171269339.1|1957755_1958919_+|alcohol-dehydrogenase
MHNFTLHTPTKVLFGKGQVAQLRGQIPADARILITYGGGSVVRSGLLAQIRHELAGMTLFEFGGIEPNPAYETLMGAVELARAERVDFLLAVGGGSVLDGTKFIAAAAHYDLAKEPWHILETVGGEVASAIPLGAVLTLPATGSEMNMGAVITRRSTGDKQHFFSPFVMPRFAVLDPVLTYTLPARQVANGVVDAFIHTLEQYLTYPVNAKVQDRFAEGLLLTLIEEGPKALVEPENYDVRANIMWSATLALNGLIGAGVPQDWATHMLGHELTALHGLDHAQTLAVVLPALLDAKREQKHAKLLQYAERVWDLRSGTEEERIDGAIAATRDFFERMGVKTRLRDYGLADANIDTLLAKLEEHGMTALGEHGDIDLVQSRHIYEAAW
>NZ_CP038448.1|WP_171269340.1|1956709_1957612_-|AraC-family-transcriptional-regulator
MSNRYADLAARLARHVTTPGITPSPVEQVNLIYTTEYHGRTPVLYQPRMIVILQGHKVGYLADQVFRYDPSHYLLMTLPLPCECECFASPEQPLIGFSLEINVATLQELLLELGDALPAPAPQKSGVHSVPLSEAMFCAAERLIALMDNPLHARVLGPQTVREMLFYALHEGGGPALQALANRHNHVGQIARVLRMIESRYADNLTMEELAREVNMSVSAFHHHFKAVTATSPLQYIKSFRLHKARMMMLHDGVKAGAAAARVGYESNSQFSREYKRFFGSTPTDQASRFRDGQLRIIEG
>NZ_CP038448.1|WP_171269341.1|1956180_1956693_-|lipocalin-family-protein
MRSLFCLLTALLLTACTGIADGIRPVTGFQLDRYLGTWYEIARLDHSFERGLERVSATYSRRDDGGVKVLNRGLQSDGSWREAEGKAYFIDKPDEARLKVSFFGPFYGGYNVIDLDPDYQLSLVTSYNHDYLWILSRSPNPPKEKVDALIAKAKGLGFATDRLIWVKQTP
>NZ_CP038448.1|WP_041206565.1|1954236_1956126_+|methyl-accepting-chemotaxis-protein
MTLSLRGKLLAASLGVVLLMAALLGIVAFHTLKSRTLGAIQSEAVNYGHAHSVAIGNWLADRRHAVNALTAVIADNPEATLVPYLLQTRTSGGFGLTYFGSVQGAMTRHDPSLNTANYDPRVRPWYQNATKAGKLIVTAPYVSVTMQQMVVTLAEPVSHQGQVIGVAGADLSLDDLIDEVLAMRVQGEGYAMLLDRSGLIVGHPQKALALKQVAELAPGLTGTTLEGWSRDGELHGATIAGREVLLSVQGVPGTDWLLAMVMYKDVLEAPFASLLWQLVGLTLVLLLVFSALLIAMFNYLFADLGRVSKALADIAHGEGDLTVQIVAQSRDEVGLLAQNFNLFVARLHGIVSRLRDVTVELAAQSRTQAAGAEERSQRVRQQQDEIVMVATAVTEMASATQEIAGNAEFAATTSGDAVRLAVAGQSQVGQSQRSISGLAGEVADASQTIHELDGHAHKISGILATISGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLSRRTHDSTAEIQQMIEALQQTTRRAVGGMETSRQLAGTSVEDAEAANQSLARINEAIGAISDMATQIAAAAEEQTSVTGEISRNTENIRHVSQTLAEQAKVEAAQAAELKSLTERLEQEIGRFRL
>NZ_CP038448.1|WP_171269335.1|1969246_1969984_+|peptidoglycan-editing-factor-PgeF
MNWIEPDWPAPGNVRALSTTRDGGLSEGVFAGLNLGAHVGDEPARVEANRARLQQAAQIPGPLNWLNQVHGTAVHFVSDQYDVAPDADAACAHEAGQACIVMTADCLPVLFCDRAGTRVAAAHAGWRGLKEGVLEGSIAAMGCEPGEILAWLGPAIGPTAFEVGGEVREAFMAEQSEAAAAFVSSSNESKWLADIYQLARLRLARAGVNAVYGGDYCTFSDSEQFYSYRRNGQTGRIASIIWLAP
>NZ_CP038448.1|WP_171269334.1|1970156_1972730_+|ATP-dependent-chaperone-ClpB
MRLDRLTSKFQVAISDAQSLALGRDHQFIEPVHLMTALLNQDGGSIRPLLTLTGMDINTLRSRLGEELDRLPKVSGVEGDVQLSNGLGRLLNVCDKLAQQRKDQFISSELFVLAALDEKGNLGELLRAQGLTKEKLEAAIDKVRGGKKIDDANAEENRQALEKYTIDLTERAELGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGAPGVGKTAIVEGLAQRIINGEVPEGLKNKRVLSLDMGALVAGAKYRGEFEERLKAVLSDLAKEEGNVILFVDELHTMVGAGKGEGAMDAGNMLKPALARGELHCVGATTLDEYRQYVEKDAALERRFQKVLVEEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAAQLSHRYIADRQLPDKAIDLIDEAAASIRLQIDSKPESLDRLERRIIQLKLEQQALMKEDDDASRKRLDLLNHELAEKEREYNELEEVWKAEKAALAGTQHIKAALEQARQDLEVARRAGDLGRMSELQYGRIPELEKQLDLATQAEMQETSLLRNRVTDVEIADVLARWTGIPVARMLEGERGKLLRMEDQLHSRVIGQEEAVDAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALAEFLFDTQDAMVRIDMSEFMEKHSVARLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQEHYAEKDYEEMKALLMELLTRSFRPEFINRIDETVVFHPLGEDHIKSIARIQLKSLMGRLESQGFEVEVSEELLTKLVHAGFDPVYGARPLKRAIQQKVENPLAQALLSGRVIPGKKLLLGADSNGLTMTQ
>NZ_CP038448.1|WP_043132834.1|1973016_1974009_-|aspartate--ammonia-ligase
MKQHYIRSQQQISFVKEMFSRQLAQQLGLMEVQAPILSRVGDGTQDNLSGHENAVQVKVKTLPEHSFEVVHSLAKWKRQTLGRFGFGPGEGIYTHMKALRPDEDRLTPIHSVYVDQWDWEKVMPGERRDLAYLQETVRGIWAAIKATERAVCAEHALTPFLPSEIQFLHSEELLTRYPDLDAKGRERAIAKELGAVFLIGIGGALSHGERHDVRAPDYDDWSSESELGLAGLNGDILVWNPVLEDSFEISSMGIRVDAEALRRQLAITGDEDRLQYDWHQDLLAARMPQTIGGGIGQSRLAMLLLQKEHIGQVQVGVWPSEMKAAIPGML
>NZ_CP038448.1|WP_043132833.1|1974162_1974624_+|transcriptional-regulator-AsnC
MSENYRIDNLDQAILTALMDNARLPYAELAKQLAVSPGTIHVRVEKMKQAGIIEGTRVQVNAKKLGYDVCCFIGINLKSAKDYPSALAKLQALDEVVEAYYTTGHYSIFMKVMTRSIDELQTVLIHKIQTIDEIQSTETLISLQNPILRDVKP
>NZ_CP038448.1|WP_171269333.1|1974719_1975484_-|transporter-substrate-binding-domain-containing-protein
MRSLLVLCLLLPCWLSARELVIGGILEPPLKWLDHSGQPRGLDVDLVTTIFGGLKVPIRIELLDSGARLTRNAEGGVYDLLLSHSYKPERESYLLYPEQAHIRHSWHFFVRKDDLGKIRYRTLADLKPWRIGVTKDFSYTPELTAAMADPAYRVQVIPINQLQLRKLIAGRIDVVPMSLVTAFAQIREEGLEGKLDYLPKPLKSSPYYHVWCKARADADTPALMAAYDAELLHMKRDGRLKALYDKYGIPYLEP
>NZ_CP038448.1|WP_161507671.1|1975567_1976104_+|hypothetical-protein
MANPEIESELDGIDRLSVCLYRLGLSLTALLLLCRGAGVLGWLVPLSPSQWLTMLVVASGLCGFCLHLYDKRVRFLLQGLAWGGLMLAACGAPAILVLGAALATLCGLAFKEQFCFAIPGIRLLPLLLPLLWLLEWIRVAWAAALVALASGLLLGLLSLAKWRMPLHFDIGDRGRYQL
>NZ_CP038448.1|WP_171269332.1|1976100_1976505_-|CBS-domain-containing-protein
MLQIRDHMSRLTHSLSPQLGLAEALDRLHQADSSGLPVLDDQKRLIGFLSEQDCIPSLLTGSYHCDSRTQVEDLMSRTPLFVSPDDSILDLARQMTGAKPKIYPVREGDKVVGIINRRQVMQALNAQMKQCQAT
>NZ_CP038448.1|WP_171269331.1|1976634_1977339_+|SDR-family-oxidoreductase
MRALVTGCGRRLGFYLCEQLVAAGWQVTGSYRSERAELAHLRALGVELVQADFAVEGEVARLATALGAHDDLALIIHNASAFEPEADEPAAQLEQFEQFYRVHMAAPFQLNRALAPQLARQHNASIIHITDIYIHAPAPQFAAYVATKAGAHSLAMSFARELAPEVRVNTIEPGPILFLDEHGDAWRQQVLARTPLAREGGLEPIWQAVTLLMANDYMTGASIRVDGGRALAVI
>NZ_CP038448.1|WP_050504434.1|1977416_1977965_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MFYLCSIGSNLDPAQHVSQAVEELLARFGQLRLSSVIQTTPVGMRSHHDFLNCLFVVQSELSAAQLKAEFVTMELAHGRDRGNPLCKVTDRPLDIDILASHERDAFAGVGVDAYLGDLLAEMYEGGRVGAHKVTLRLRTSKVFAQQAFGQQPVALRQPTDERQELSAVPPDMPAHQATIRHH
>NZ_CP038448.1|WP_106885551.1|1978090_1978183_+|YnhF-family-membrane-protein
MSVEMKWALLTASGALAVILIICLASVGLA

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Crispr_ID: NZ_CP038448_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_4

2739151-2739322

Orphan

Consensus_repeat	Method
CAATGCCAGGGCGGCCATCCTCAGATTAGTATCAGCA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP038448_4

>merge|NZ_CP038448|4|2739151-2739322|PILER-CR
CAATGCCAGGGCGGCCATCCGCCAGTATCAACAGGGCAGAGAGTGAGTGGGCAGGGGGGCAATGCCAGGGCGGCCATCCTCAGATTAGTATCAGCAGGGCAGGGCGTGAGTGGGCAGGGGGGGCCAGAGGTTCCCCAATGCCAGGGCGGCCATCCTCAGGTTAGTATCAGCA

>NZ_CP038448|4|1|2739151-2739322|PILER-CR
CAATGCCAGGGCGGCCATCCGCCAGTATCAACAGGGC	AGAGAGTGAGTGGGCAGGGGGGCAATGCCAGGGCGGCCA
TCCTCAGATTAGTATCAGCAGGGCAGGGCGTGAGTGG	GCAGGGGGGGCCAGAGGTTCCCCAATGCCAGGGCGGCCA
TCCTCAGGTTAGTATCAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_005328660.1\|2735265_2736054_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP038448.1\|WP_161507494.1\|2732851_2734105_-\|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl\|CDD\|225930
NZ_CP038448.1\|WP_042649266.1\|2734101_2735010_-\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224995
NZ_CP038448.1\|WP_005328663.1\|2736073_2736229_-\|entericidin-A/B-family-lipoprotein	unknown	unknown	gnl\|CDD\|227797
NZ_CP038448.1\|WP_005328671.1\|2739375_2740200_-\|polyphosphate-kinase-2	unknown	unknown	gnl\|CDD\|213852
NZ_CP038448.1\|WP_042649270.1\|2742233_2743517_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270451
NZ_CP038448.1\|WP_048824741.1\|2743583_2744474_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_CP038448.1\|WP_041206300.1\|2744475_2745303_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_CP038448.1\|WP_042649267.1\|2736245_2737307_-\|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|369642
NZ_CP038448.1\|WP_114523370.1\|2747686_2748718_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NZ_CP038448.1\|WP_161507496.1\|2727922_2728813_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_CP038448.1\|WP_052833535.1\|2746562_2747525_+\|family-43-glycosylhydrolase	unknown	unknown	gnl\|CDD\|350141
NZ_CP038448.1\|WP_042650707.1\|2730400_2731351_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187549
NZ_CP038448.1\|WP_082030028.1\|2740242_2740605_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380511
NZ_CP038448.1\|WP_005328654.1\|2732226_2732859_-\|aldolase	unknown	unknown	gnl\|CDD\|181241
NZ_CP038448.1\|WP_082030029.1\|2740617_2740785_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_CP038448.1\|WP_161507495.1\|2731391_2732165_-\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|226149
NZ_CP038448.1\|WP_042649269.1\|2741090_2742167_+\|cellulase-family-glycosylhydrolase	unknown	unknown	gnl\|CDD\|226444
NZ_CP038448.1\|WP_005328684.1\|2745375_2746476_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_CP038448.1\|WP_005328642.1\|2728898_2730404_-\|gluconate-permease	unknown	unknown	gnl\|CDD\|308194

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_005328660.1\|2735265_2736054_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	8.35023e-91
NZ_CP038448.1\|WP_161507494.1\|2732851_2734105_-\|four-carbon-acid-sugar-kinase-family-protein	gnl\|CDD\|225930	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown].	4.15891e-153
NZ_CP038448.1\|WP_042649266.1\|2734101_2735010_-\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	3.42065e-91
NZ_CP038448.1\|WP_005328663.1\|2736073_2736229_-\|entericidin-A/B-family-lipoprotein	gnl\|CDD\|227797	COG5510, COG5510, Predicted small secreted protein [Function unknown].	5.02301e-06
NZ_CP038448.1\|WP_005328671.1\|2739375_2740200_-\|polyphosphate-kinase-2	gnl\|CDD\|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	9.29927e-138
NZ_CP038448.1\|WP_042649270.1\|2742233_2743517_+\|extracellular-solute-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09091e-60
NZ_CP038448.1\|WP_048824741.1\|2743583_2744474_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	6.87883e-78
NZ_CP038448.1\|WP_041206300.1\|2744475_2745303_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.25405e-69
NZ_CP038448.1\|WP_042649267.1\|2736245_2737307_-\|PQQ-dependent-sugar-dehydrogenase	gnl\|CDD\|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	1.53422e-170
NZ_CP038448.1\|WP_114523370.1\|2747686_2748718_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	7.6476e-16
NZ_CP038448.1\|WP_161507496.1\|2727922_2728813_-\|EamA-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	6.39784e-13
NZ_CP038448.1\|WP_052833535.1\|2746562_2747525_+\|family-43-glycosylhydrolase	gnl\|CDD\|350141	cd18820, GH43_LbAraf43-like, Glycosyl hydrolase family 43 proteins similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans GbtXyl43B. This uncharacterized glycosyl hydrolase family 43 (GH43) subgroup belongs to a subgroup which includes enzymes with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55) and possibly bifunctional xylosidase/arabinofuranosidase activities, similar to Lactobacillus brevis alpha-L-arabinofuranosidase LbAraf43 and Geobacillus thermoleovorans IT-08 beta-xylosidase / exo-xylanase (GbtXyl43B). It belongs to the glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) which includes family 43 (GH43) and 62 (GH62) families. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.45973e-141
NZ_CP038448.1\|WP_042650707.1\|2730400_2731351_-\|SDR-family-oxidoreductase	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.66037e-133
NZ_CP038448.1\|WP_082030028.1\|2740242_2740605_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|380511	cd06288, PBP1_sucrose_transcription_regulator, ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.74396e-25
NZ_CP038448.1\|WP_005328654.1\|2732226_2732859_-\|aldolase	gnl\|CDD\|181241	PRK08130, PRK08130, putative aldolase; Validated.	8.54754e-134
NZ_CP038448.1\|WP_082030029.1\|2740617_2740785_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.88174e-07
NZ_CP038448.1\|WP_161507495.1\|2731391_2732165_-\|TIM-barrel-protein	gnl\|CDD\|226149	COG3622, Hfi, Hydroxypyruvate isomerase [Carbohydrate transport and metabolism].	1.05665e-135
NZ_CP038448.1\|WP_042649269.1\|2741090_2742167_+\|cellulase-family-glycosylhydrolase	gnl\|CDD\|226444	COG3934, COG3934, Endo-beta-mannanase [Carbohydrate transport and metabolism].	5.39545e-05
NZ_CP038448.1\|WP_005328684.1\|2745375_2746476_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	4.38217e-172
NZ_CP038448.1\|WP_005328642.1\|2728898_2730404_-\|gluconate-permease	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	2.01208e-139

>NZ_CP038448.1|WP_042649267.1|2736245_2737307_-|PQQ-dependent-sugar-dehydrogenase
MLRLLALLLVCLVAQVRALTLTPLVEGLNHPWGLVLLPDGGYLVGERPGRLLHIDAAGKRHLISGLPPLAATGQGGLLDLALDGEGWLYLSYSEPGDGGAGTAVARARLQKEALIDWQLLFRQEPKVAGGAHFGSRLALTEDGYLFITLGDRYSERERAQTLDNHLGKTVRLHKDGRVPADNPFVKTAGALPEIWSLGHRNMQGAALRPGSQQFWAHEHGPQGGDEVNLILPGHNYGWPKVTFGEEYGGGKIGLGQSAPGMTPPRWIWVPSIAPSGMTFYQGELFKEWRGDLLVGALRGQALLRLHLDGDKIVSAERLLTDLGERIRTVKEGPDGALYLLTDSGQGRLLKLTP
>NZ_CP038448.1|WP_005328663.1|2736073_2736229_-|entericidin-A/B-family-lipoprotein
MNKYRTLLVLCASLWLLGCNTIHGVGRDIEKAGEVIQGSANLTSEHQAGKE
>NZ_CP038448.1|WP_005328660.1|2735265_2736054_+|DeoR/GlpR-transcriptional-regulator
MIPVERQQRILQLLAERGVVSIMELTDWLQVSHMTIRRDIQKLEEQGRVLSVSGGVSLSQRIKSEPSHAAKRSLMQGAKLAIARLAADQVAEGSTVYLDAGTTSLELARELALREDLMIVTNDFMVCAYLIEHGRCRLYHTGGQVIRENQSCAGEATAHFLRNLHLDVAFLSASSWDGQGISTPSEQKVPVKRAVVESAASRILICDSSKYGKVGTFNVVGWDAIDQVITDEQLPQSARDVLAQHGVRVTMAPLASLASGVE
>NZ_CP038448.1|WP_042649266.1|2734101_2735010_-|NAD(P)-dependent-oxidoreductase
MSTSYHVAVIGLGAMGMGAARSCLRAGLTTYGIDLSEQARSQLQQAGAAAVMADARPLAETLDAVLLLVVNAAQVRRILFGEEELARHLKPGTAIMVSSTIAAEEASTLAAELAQLGLPMLDAPVSGGAIKADAGEMTVMAAGSDAAFDKLAPVLDAVSGKLYRVGSEPGQGSTVKIIHQLLAGVHIAVAAEAMALASRAGVSLDLMYDVVTHAAGNSWMFENRMPRVLTGDYQARSAVDIFVKDLTLVADTAKALRFPLPLASTALNMFLGASNAGHGQEDDSAVIKIFSGIQLPGQEDQA
>NZ_CP038448.1|WP_161507494.1|2732851_2734105_-|four-carbon-acid-sugar-kinase-family-protein
MKLGVIADDFTGATDIAGFLVENGLSTLQLAGVPEHDGDLPQVDAVVISLKSRSCPAGEAVRDSLAALAWLKARGCPRIYQKYCSTFDSTAAGNIGPVTDALLAALGHDFTLICPALPVNGRTVYQGNLFVGAQPLAESGMRHHPITPMTDSNLLRLMEGQAQGRAGLVPFTTIAQGPDAIANAFEQLTQAGVRYAVVDTLTEQHLLDIATAALDMPLLTGGSGLAIGLARQLGSGDLQGAREAGWPRGTRAVVLSGSCSEMTNRQVARYRQHAPALALDVVRCLEDADYPAELARWVLAQPLTPAPLVYATTSPVELARIQETHGQQAASDAVEHCFARLAQLLQDAGVDRFIIAGGETSSRVTQALGVKAFHIGPQIAPGVPWVRAIDAPLSLALKSGNFGSDDFFDKAQEYFHD
>NZ_CP038448.1|WP_005328654.1|2732226_2732859_-|aldolase
MTEQALRDTMVMLGASLFQRGYATGGAGNLSALLPDGTLIATPTGSCLGRLSADRLSHVNLQGEHLGGDRPSKEVAFHLAIYHNNPDCRAVVHLHCTYLTALSCLEGLDPANVIRPFTPYYVMRVGQLPLIPYYKPGDARIAEELGRRAPEGNAFLLANHGPVVTGKDLVDAVNNMEELEETARLALMLHGQSIRYLSEPEITELRSLKP
>NZ_CP038448.1|WP_161507495.1|2731391_2732165_-|TIM-barrel-protein
MSKFAANLTMLFTELPFLERFAAAREAGFEAVEFLFPYEWPAAELGRLLREHGLSLALFNMPPGNWGAGERGMAAIPGREAEFRAHLPSVRDYALALGCTKVHAMSGIVDPAHSLAAHRQTLIENIRFAADFLAADGIKVLLEPLNDRDVPGYFLAHQLDALALVQEIDRPNVGVQLDLYHAQIMDGDLTRLIGKLGPAIGHVQIASVPDRHEPDEGEIAYPHLFKVLAQAGYHDWIGCEYNPRAGTREGLGWLTQQ
>NZ_CP038448.1|WP_042650707.1|2730400_2731351_-|SDR-family-oxidoreductase
MQIIITGGGGFLGQKLARALLQGPHPFTELLLVDIQQPQSPLPDPRVRCLKADLTETGVAESLISERTTVVYHLAAIVSSHAEQDFDLGWKVNLDTTRTLLEACRHTRPGIRFVFTSSLAVYGGPLPELVNDGTALTPTSSYGAQKAMGELLVNDYSRKGYVDGLVLRLPTICVRPGKPNRAASSFVSSIIREPLQGENALCPVSPELRLWLSSPATVVANFLLAARLPATGDARSINLPGISVTVGEMLEALARAGGQAARDRVQFATDPAIERIVASWPGRIDNQRASALGFAADRTFADIIDSFITHDMQEAS
>NZ_CP038448.1|WP_005328642.1|2728898_2730404_-|gluconate-permease
MSDIPTPIIGLVIAVFVLVFLVVRTRVHALIAMLAAACIAGITGGMSIDKTLTVITQGFGSTLGSIGIVIGLGVMMGRLLEVSGAAEQIAYSFIKWLGKRREEWALAITGYIVSIPIFVDSAFVILYPVAKALAKSGKRSLLTLGVALAGGLVVTHHTVPPTPGPLGVAGLFGVDIGAMLLMGMALAIPCVLGIVFYAQWLDKKYPEFGANAAQTPDELQATYEQYLKEKEGKTLPSLTLSLLPILVPIVLIFVKAIFTTLATLEGMDGLMANPLVQGINFIGTPIIALAISVLLAVYTLVPHMDRHATAARLEEGLQSAGIILLVTGAGGALGAVLRDSGAGQQLAEQIAQLPISPILIPFIVATLVRLIQGSGTVAMVTAASISAPILAQIPGVNMLLAAQAATMGSLFFGYFNDSLFWVVNRMMGISDVKQQMIVWSIPTTIAWAIGGTGVALLNLVFGSGGTWFDPVLPLLVLALIVWYVRGQSLAPAASAVPSRES
>NZ_CP038448.1|WP_161507496.1|2727922_2728813_-|EamA-family-transporter
MSASSWWDRSTGFALLTILLWASLAALTSRITSVSPLVLVGLVLFFCGAGALPFWRQWRASPLTWLVTITALLLYHLLLFMSFRHAPVLEANLINYLWPLCIILFTPLLLPGHPLSLHHLLAGALGLAGSVLVMVDGRLQLQQAHLPGYLLALGAAIVWGAYSVLSRRLPPAPAVVTAAACLPAGLLALLLAWGLEGPLPFDQIPQADWLLIAGLALGPMGAAFVTWYLALRDGDPRRIGALAYLTPLLSTLLLVWLNGEQLTPRHLLAGALIMGGALLGLLVKTPKTRPVAEPLS
>NZ_CP038448.1|WP_005328671.1|2739375_2740200_-|polyphosphate-kinase-2
MASKKKSTTEQPAPAAESKPLGNKAYEKELRRLHVELVKLQQWVVHKGLKVCIVFEGRDGAGKGGTIKAITERVSPRVFRVIALPAPTEREKSQLYFQRYIPHLPAAGEIVIFDRSWYNRAGVERVMGFCSQEASDKFLAGVPMVEQAMVDSGIILLKYWLEVTPQEQERRLRDRIDDGRKIWKLSPMDIKSFDRWDDYTRARDAMFTATDTAWAPWFVARSEDKKRVRLNIISHLLAHVPYEELPAEPVKLPKRKIGKVKASEHPFRVIPELF
>NZ_CP038448.1|WP_082030028.1|2740242_2740605_-|substrate-binding-domain-containing-protein
MPAPQWVRVANWPLREAYEQTRQLLALPNTPDAVFCCSDYMTQGCYQAIAEAGLRIPEDILVAGHDNQMLANEMVPLCLLDAPNEIHKATHDFHLIPVPPRHFASVPSPALDYTQDVGRR
>NZ_CP038448.1|WP_082030029.1|2740617_2740785_-|LacI-family-DNA-binding-transcriptional-regulator
MNKQRITMSAIAAAAGVSQSTVSLVLNGSSAVKLSFRGNPGGRPTTYGWRDIAKP
>NZ_CP038448.1|WP_042649269.1|2741090_2742167_+|cellulase-family-glycosylhydrolase
MAVQQWSTEQAWQWWSKQPWLRGFNYLPRTAVNWTEMWQRETFDLPTIRQELAWAREVGYNTLRTNLPFIVWQVDRDGLIARIDDFLAVAAAEGISVMLTPMDDCGFSGDHPYLGPQKEPVKNLHNSQAAASPGRNVVMDVTQWCELERYIKDVVGMFAQDERILVWDLYNEPTNRGIFRGPNQHEEFDPAMEPYSHHLMELAFSWAREANPCQPLTVCAWHAANHFSPDDPIFTHPTDLRAMALSDVISFHAYQSLELLEKSLEIVATYDRPLLCTEWLARHAKSFMHEQLPIFKERKIACYQWGLVKGRTQTHLPWPNIQRAVPEYADTWFHDLLEADGSPYDEREVALIQSLTTE
>NZ_CP038448.1|WP_042649270.1|2742233_2743517_+|extracellular-solute-binding-protein
MKKIKLLALLVAGATLSPITLAQTTLQYWTLLNGGDGARMKQLVDGFNASQGDYKIETTTLNWGEPFYTKLKTASAMGSGPDMATIHLSKISGLTQTQGLEPINPEVLKQAGYDSNQLFPLLWKQSNVDDKTYALPIDTHAMVLYYNKRIAAKAGLLDEQGRLKPIASLAQFDAALKSVKEQGAMGLSMETSPMSYMPYRLWLSMISQQGGKTIENNEFVYGEAGRQAMAAMARWYADGYATKGLDYASSTTEFMTGRSALMLNGVWELPSVTDGMKSGKLGFEVGIASLPSFFNGSRAAWADSHALAIPRNKDKPISDEKVLGIAKFANYINQNALTWAEGGHIPAYEPTVATQAFKEMPLLADYVSETASNIVYDPDGWYSGAAGPLQAAASKYFPAALTGQLPIEKALQMFERDAGKFMSRPAR
>NZ_CP038448.1|WP_048824741.1|2743583_2744474_+|sugar-ABC-transporter-permease
MDNKDTARTTVGRFGALMTPWLMLAPFLLAFLLFFVIPALQTLQLSFTDSGLTETHGYVGFANYVELLQDPSFWDSLLQTAYFALLTVIPLTALGLVMAMLICRLTRFAGLVQAIFFIPNILPIAVMAMIGGWMLHPTFGVVNLVAGTEIAWFNDPDFAMPMVAIATIWWTVGFNVLLFMAALKNIPQDLYEAARLDGASEWGIFRYITWRQLRPVTVMVFGLQLVASLKIFGQTYLLTGGGPFDSTKVVLHYMYETGFVNQNAGYASAIAVVFVLIVLLILVLQSLANRFINRRG
>NZ_CP038448.1|WP_041206300.1|2744475_2745303_+|carbohydrate-ABC-transporter-permease
MNSKLTFTALLAITLTVLLCLLWGAPLLWAISTALRPEAQTVAGLQWLPDPVIFDAFIKVLTMGDLPVFFMNSVVTSLAVTLVTLLITVLAAYSFSQLRFKGANLLFWCCMFGIIFPFEALVIPLFRQVYHMGLADSLGGIILPQVVSPMVLFVLKRFFDQIPKDFREAAILDGAREWQVLLRVYLPLSRNIIYAMAIITFMGAWNNFLWPFLVVSSTENMTIPIGLTQLNDTYGVRYAQNMASALIGGLPVAILYVMFQKRVASGFLAATGLKG
>NZ_CP038448.1|WP_005328684.1|2745375_2746476_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MSSVSLKHIKKTYPNGNAVIHGVDLEIEQGEFVVFVGPSGCGKSTLLRMIAGLEDISAGDLHIGNLRANELDAAKRGVAMVFQSYALYPHLTVAENMGFSLLFNNTPKAEIETKVNRVAETLQLAHLLERKPAELSGGQRQRVAIGRAIVREPEVFLFDEPLSNLDAALRGQMRTELARLHQKLGTTMIYVTHDQVEAMTLGDRIVVFNKGHIEQVGSPLDLYQRPATEFVATFLGMPKMNMLTCKLKGKDGDLWQLTPGKGIEVTASESWFDCTGQSNIKIGIRPEHLLVGVEGAPEAHLHGRVSLVENLGDAAILHIKCEGIERLLLAKVNTDRRVPSCDEAVSLTVALEYIHLFGEQGQSLRR
>NZ_CP038448.1|WP_052833535.1|2746562_2747525_+|family-43-glycosylhydrolase
MPAQASSTFTNPILGDGADPWVVRHDDGFYYYTQTTGSDIMLWRTKDITDLENAEHKVVWMPAQGAVNGTHLWAPELHLLDGRWYIYFAASDGDMARQRMYVLQSKGVDPFGEYTFPAGTQEGKMADASDKWAIDGTVLDYRGERYFIWSGWEGEVNNQQRLYIARMASPWQLAGPRVEISRPELAWERIGTPQVNEAPQVLLSPGGRLFLTYSASGSWTDDYCLGLLALEGEDPMNPAHWRKRPQPVFSKDEALGVYGPGHNGFFIDDGGRPWLIHHAAKFKGAGWNREIHLQPFDWDARGLPSFGLPVGTSRQQMAPR
>NZ_CP038448.1|WP_114523370.1|2747686_2748718_+|IS630-family-transposase
MPILPPLPRPQRRRIHKIIHATRDKGHARRLMAILLLHEGRTVTDVHHLTGAARSTIGRWLRWYRDEGIDALEALPAGRAPVLPVAKIVTLLVLLMQFSPQDFGYQRSRWCTELLAIKINRLTGLNMAASTLRRWLPRMGIVWRRPVPTLRIKDPAYQEKMADIDAALARCDADNPVFYEDEVDIDLNPKLGADWMFRAQQKRVVTPGQNAKHYLAGVLHAGNGRVLYVSGIKKNSSLFIAMLEKLRRHYRRAKTITLILDNYIIHKSKQTERWLKKNPKFCLVFQPVYSPWVNHIERLWHKLHETITRNHQCRGMANLLARVKHFMDTVSPFPGNGYGTAKV

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Crispr_ID: NZ_CP038448_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_5

3143504-3143608

Orphan

Consensus_repeat	Method
CTCCGACGAAGTGGCCGCGCTGCTCTGATCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_5

>merge|NZ_CP038448|5|3143504-3143608|CRISPRCasFinder
CTCCGACGAAGTGGCCGCGCTGCTCTGATCGTCAGCAGCAACTAGCGATAGGAGGTGCACCACAACGGTGTCACCTCCGACGAAGTGGCCGCGCTGCTCTGATCG

>NZ_CP038448|5|4|3143504-3143608|CRISPRCasFinder
CTCCGACGAAGTGGCCGCGCTGCTCTGATCG	TCAGCAGCAACTAGCGATAGGAGGTGCACCACAACGGTGTCAC
CTCCGACGAAGTGGCCGCGCTGCTCTGATCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_042650217.1\|3132429_3132876_-\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|236773
NZ_CP038448.1\|WP_005325677.1\|3155377_3155806_-\|ferric-iron-uptake-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236527
NZ_CP038448.1\|WP_042650225.1\|3146791_3147937_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|183010
NZ_CP038448.1\|WP_005325673.1\|3156597_3157122_-\|flavodoxin-FldA	unknown	unknown	gnl\|CDD\|236439
NZ_CP038448.1\|WP_042650228.1\|3156050_3156551_+\|DUF4442-domain-containing-protein	unknown	unknown	gnl\|CDD\|373120
NZ_CP038448.1\|WP_042650224.1\|3145572_3146787_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|366120
NZ_CP038448.1\|WP_042650223.1\|3143878_3145504_+\|phosphoethanolamine--lipid-A-transferase	unknown	unknown	gnl\|CDD\|183224
NZ_CP038448.1\|WP_042650227.1\|3150595_3153259_+\|carbohydate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|119337
NZ_CP038448.1\|WP_042650218.1\|3132993_3133908_-\|hydrogen-peroxide-inducible-genes-activator	unknown	unknown	gnl\|CDD\|176103
NZ_CP038448.1\|WP_005325685.1\|3147946_3148747_-\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|179028
NZ_CP038448.1\|WP_171269495.1\|3136723_3137482_-\|ATP-dependent-zinc-protease	unknown	unknown	gnl\|CDD\|226553
NZ_CP038448.1\|WP_005325679.1\|3153598_3155260_+\|glutamine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235424
NZ_CP038448.1\|WP_042650219.1\|3137564_3138542_-\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	unknown	unknown	gnl\|CDD\|237898
NZ_CP038448.1\|WP_042650221.1\|3139662_3140511_-\|DUF72-domain-containing-protein	unknown	unknown	gnl\|CDD\|182366
NZ_CP038448.1\|WP_042650226.1\|3149018_3150473_+\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP038448.1\|WP_005325703.1\|3135181_3136720_-\|inactive-transglutaminase-family-protein	unknown	unknown	gnl\|CDD\|379600
NZ_CP038448.1\|WP_042650216.1\|3132053_3132347_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_042650222.1\|3140943_3142722_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP038448.1\|WP_042650220.1\|3138538_3139279_-\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	unknown	unknown	gnl\|CDD\|273244
NZ_CP038448.1\|WP_005325705.1\|3134212_3135178_-\|alpha-L-glutamate-ligase-like-protein	unknown	unknown	gnl\|CDD\|274070

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_042650217.1\|3132429_3132876_-\|C40-family-peptidase	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	3.57497e-42
NZ_CP038448.1\|WP_005325677.1\|3155377_3155806_-\|ferric-iron-uptake-transcriptional-regulator	gnl\|CDD\|236527	PRK09462, fur, ferric uptake regulator; Provisional.	1.22597e-102
NZ_CP038448.1\|WP_042650225.1\|3146791_3147937_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|183010	PRK11170, nagA, N-acetylglucosamine-6-phosphate deacetylase; Provisional.	0
NZ_CP038448.1\|WP_005325673.1\|3156597_3157122_-\|flavodoxin-FldA	gnl\|CDD\|236439	PRK09267, PRK09267, flavodoxin FldA; Validated.	2.1061e-106
NZ_CP038448.1\|WP_042650228.1\|3156050_3156551_+\|DUF4442-domain-containing-protein	gnl\|CDD\|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	1.61071e-28
NZ_CP038448.1\|WP_042650224.1\|3145572_3146787_-\|ROK-family-protein	gnl\|CDD\|366120	pfam00480, ROK, ROK family.	1.61794e-71
NZ_CP038448.1\|WP_042650223.1\|3143878_3145504_+\|phosphoethanolamine--lipid-A-transferase	gnl\|CDD\|183224	PRK11598, PRK11598, putative metal dependent hydrolase; Provisional.	0
NZ_CP038448.1\|WP_042650227.1\|3150595_3153259_+\|carbohydate-binding-domain-containing-protein	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP038448.1\|WP_042650218.1\|3132993_3133908_-\|hydrogen-peroxide-inducible-genes-activator	gnl\|CDD\|176103	cd08411, PBP2_OxyR, The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily. OxyR senses hydrogen peroxide and is activated through the formation of an intramolecular disulfide bond. The OxyR activation induces the transcription of genes necessary for the bacterial defense against oxidative stress. The OxyR of LysR-type transcriptional regulator family is composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The C-terminal domain also contains the redox-active cysteines that mediate the redox-dependent conformational switch. Thus, the interaction between the OxyR-tetramer and DNA is notably different between the oxidized and reduced forms. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.19605e-79
NZ_CP038448.1\|WP_005325685.1\|3147946_3148747_-\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.38008e-175
NZ_CP038448.1\|WP_171269495.1\|3136723_3137482_-\|ATP-dependent-zinc-protease	gnl\|CDD\|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	1.56896e-49
NZ_CP038448.1\|WP_005325679.1\|3153598_3155260_+\|glutamine--tRNA-ligase	gnl\|CDD\|235424	PRK05347, PRK05347, glutaminyl-tRNA synthetase; Provisional.	0
NZ_CP038448.1\|WP_042650219.1\|3137564_3138542_-\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	gnl\|CDD\|237898	PRK15068, PRK15068, tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB.	0
NZ_CP038448.1\|WP_042650221.1\|3139662_3140511_-\|DUF72-domain-containing-protein	gnl\|CDD\|182366	PRK10302, PRK10302, hypothetical protein; Provisional.	7.30529e-105
NZ_CP038448.1\|WP_005325703.1\|3135181_3136720_-\|inactive-transglutaminase-family-protein	gnl\|CDD\|379600	pfam14402, 7TM_transglut, 7 transmembrane helices usually fused to an inactive transglutaminase. A family of seven transmembrane helices fused to an inactive transglutaminase domain. The transglutaminase domain is predicted to be extracellularly located. Members of this family are associated in gene neighborhoods with a pepsin-like peptidase and an ATP-grasp of the RimK-family. The ATP-grasp is predicted to modify the 7TM protein or a cofactor that interacts with it.	7.905e-151
NZ_CP038448.1\|WP_042650226.1\|3149018_3150473_+\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP038448.1\|WP_042650222.1\|3140943_3142722_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP038448.1\|WP_042650220.1\|3138538_3139279_-\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	gnl\|CDD\|273244	TIGR00740, tRNA_cmo5U34-methyltransferase, tRNA (cmo5U34)-methyltransferase. This tRNA methyltransferase is involved, together with cmoB, in preparing the uridine-5-oxyacetic acid (cmo5U) at position 34. [Unknown function, Enzymes of unknown specificity].	1.7822e-134
NZ_CP038448.1\|WP_005325705.1\|3134212_3135178_-\|alpha-L-glutamate-ligase-like-protein	gnl\|CDD\|274070	TIGR02291, conserved_protein_of_unknown_function, alpha-L-glutamate ligase-related protein. Members of this protein family contain a region of homology to the RimK family of alpha-L-glutamate ligases (TIGR00768), various members of which modify the Glu-Glu C-terminus of ribosomal protein S6, or tetrahydromethanopterin, or a form of coenzyme F420 derivative. Members of this family are found so far in various Vibrio and Pseudomonas species and some other gamma and beta Proteobacteria. The function is unknown.	2.73076e-160

>NZ_CP038448.1|WP_042650222.1|3140943_3142722_+|aspartate--tRNA-ligase
MRSIYCGQVNEAHAGQTITLCGWVHRRRDLGGLIFIDMRDREGIVQVFFDPDKPDAFALASELRGEFCIQVTGVVRTRPDSQRNSDMATGAIEVFAHELTIINRAEPLPLDFNQVNSEEVSLKYRYLDLRRPEMAKYLKTRAKASAFVRRFMDEQGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREIMEEMIRKLWMHILNVDLGDFPIMTFDEAMRRFGSDKPDLRLPMELVDVADLLTAVEFAVFAGPANDPKGRVAALKVPGGAELSRKQIDEYTKFVGIYGAKGLAWMKVNEAANGIEGVQSPVAKFLTDEIVREILARTGAADGDILFFGADSKKVVCDAMGALRLKVGRDLGLVENVWKPLWVIDFPMFEEDGEGGLAAMHHPFTAPSNLGPSELKANPLGAYANAYDMVINGYEVGGGSVRIHNSEMQSTVFDILGITPDEQRLKFGFLLDALKYGTPPHAGLAFGLDRLSMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANQAQLTELAIATVAKADAKADA
>NZ_CP038448.1|WP_042650221.1|3139662_3140511_-|DUF72-domain-containing-protein
MSLYLGLPQWSHPAWPGQLLGVGARPAEHLAHYARVFNTVEGNTTFYASPTPDTVRRWADAVPPQFRFSFKFPKEISHQSDLVSAGKQVAAFIALLAPLHGQLGLLKLQLPARFGPAGLPRLTAFFESLPPDFTYALEVRHPDFFAKGEAERALNRLLMDRGINRIMLDSRPLFSVPATTPALVDAQGKKPRLPVHLLATANSPVVRLIGLPHPEDNHPFLPSWLPRWQQWLAEGKDLYLFIHTADNARAPELARQVSRLLGQEMAPWPGENDRARQGLLPF
>NZ_CP038448.1|WP_042650220.1|3138538_3139279_-|carboxy-S-adenosyl-L-methionine-synthase-CmoA
MHDQIFAAPIAQLGDFCFDEQVVDVFPDMIQRSVPGYSNIISAIGMMAARYAQPQSRLYDLGCSLGAATQAMRRHVNQPGCQITAVDLSHPMIERARAHLSGFKSEVPVELVEADICDIAIENASVVVLNFTLQFVEPEKRAALIARIHDGLRPGGILILSEKFRFEDEQVNALLIDLHLDFKRANGYSELEISQKRTALENVMRTDSLETHRARLRDAGFTHQDLWFQCFNFGSMIAIKSSDTQP
>NZ_CP038448.1|WP_042650219.1|3137564_3138542_-|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB
MIDFANFYQLIAKNRLSHWLHTLPAQLHAWQHDNLHGDLPRWNRALNKLPAVAPRKVELKSRVEIGSAESLGEGERKKTESLLRQFMPWRKGPFQVHGIHIDTEWRSDWKWERVLPHISPLAGRYVLDVGCGSGYHLWRMVGEGAKLAVGIDPSPLFLCQFEAIRHFAGNDQRAHLLPLGIQELPELRAFDTVFSMGVLYHRKSPIEHIEQLRNQLKDDGELVLETLVIDGGVNDVLVPTDRYGKMRNVWFIPSSAALKLWVERCGFSDVRIVDENMTSTDEQRRTDWMINESLSDYLDPDDPALTVEGYPAPKRAVLIARKAKD
>NZ_CP038448.1|WP_171269495.1|3136723_3137482_-|ATP-dependent-zinc-protease
MTLLSLLSLGGCVSMEKAPPAPTLTLAELRNEITLSEQRLQTSMEQQQKQYVQQQHLLVQLNTDVTNMKESVKKVDSKLATLPPEPPKPMAIPTEKCPAPSQGHTVDGKLLVGEAEWIWVDAANDAFQARVDTGATTSSISAQEITIFERNGKNWVRFFLSHQEMDDKIQIEAPLVRHVRVRQASADDLDRRPVVRLTVRIGDMTEKAEFTLKDRSDMTFPVLLGREFLKDIAVVDVAREYIQPKPKLKDVK
>NZ_CP038448.1|WP_005325703.1|3135181_3136720_-|inactive-transglutaminase-family-protein
MVSRKPFYLLVALLFIVGLGMTFYHHVALDVPLTPGEKRQIWSIEAKLEFEATGEPVIASLAIPGTQPGFTLMNENAASPGYGLSFVEKDGDARAEWSIRTASGRQELYYRVDMMADAHAKPAANPLPPAIEKQIESEPYATAMKQILERAQERSADGYTLTREIIKEIEKQEQNAELLKSHKSRASLIAELLNNAEVPARVVHALSLEDGRRRQELVDYLQVFNSPTDYKLFNPQTGEQGQPGNLLLWEYNSGALLDVTGGHNSRVTFSMIEQEQPVNVALAQKFEKSEMMNFSIHSLPLEEQALFKGLLLIPIGVLMVVFLRVLVGIKTSGTFMPVLIAVAFIQTSLVTGLIGFLLIVGTGLVIRSYLSRLNLLLVARISAIIIMVISMIGIFSAFAFKLGLTDGMKITFFPMIILSWTIERMSILWEEEGPKEVFRQGGGSLLVAVIAYLAMDNELIRHLTFNFLGLQLVLMATVLVMGNYTGYKLSELKRFKPLVDEMKSGATPGKDK
>NZ_CP038448.1|WP_005325705.1|3134212_3135178_-|alpha-L-glutamate-ligase-like-protein
MWFWQKYTSPWSLSQAGILGMNKRNHSYISRYNPRRLYPLVDDKLKTKRIALDAGVTVPELIGTIREQHDVTRITELVKDWPGFCIKPARGSGGKGILVILRQEEGSFYKPNGSASTGQDLERHVSNILAGLYSLGGKPDVALVEGLINFDDVFDGYSFEGVPDARVIIFKGFPVMAMMRLSTAASDGKANLHQGAVGVGLCLRTGRALRAVQFGNPLRHHPDTGLDLYDLKVPHWDTLLTLAASCYEMSGLGYIGTDMVLDKFRGPMLLELNARPGLAIQIANGRGLVPNLKTIEKLGQVKMNVEQRVNFAKDHFGIFDE
>NZ_CP038448.1|WP_042650218.1|3132993_3133908_-|hydrogen-peroxide-inducible-genes-activator
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVARARNLLSDARDLMELGQQQGGVMHGTVRLGCIPTIAPFLLSKLLQVCGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFHCKTVGQDPFHMVMPSNMAATLHMPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLGTTFLPQMAIDAGILENSDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKIAELLTPLITPKAAD
>NZ_CP038448.1|WP_042650217.1|3132429_3132876_-|C40-family-peptidase
MFRTLLPPLLALLVVACSSTPEPPPARQASAFDGFYQQWRGVPYRMGGTNRAGLDCSAFTQLAYQQVLGFTLPRTTESQASLGRPVDRYRLQHGDLVFFKTGWQQYHVGVYTGSGEFIHASTSKGVIRSRLDNVYWNSRYWQARRLTQ
>NZ_CP038448.1|WP_042650216.1|3132053_3132347_+|hypothetical-protein
MTRELHSLLARLDDVIERMPDSFNTYEFTQKLALQHQREYFAAGHSLAEQDKNLLRLLHEKIALALASHDGVIEGALLPCVTPWGERATSPRWHRKH
>NZ_CP038448.1|WP_042650223.1|3143878_3145504_+|phosphoethanolamine--lipid-A-transferase
MRLTLGVMKVNLLLVLLFALVFNWPIFLHFYRILTALEHVKAGFALSIPLVLIAALNAVFLPFTFRYLLKPFFILLIMTASLVSYAMLKYGIIFDVGMVQNILETNSGEATSYLNASVVLWFLLTAVLPVLGLLWIKVEYPTPWYKGLGLRLGSIALSLLFLVGVAALYYQDYASVGRNNHSIVKEIVPSNYVRGLYRYARDILFATPVPYEPIGTDARVVAKSDKPTLMFLVVGETARSQNYSLNGYQKETNGFTMKEPDLVSFRDVRSCGTATAVSVPCMFSNLTRREYDETLAKSRDGLLDVLQHAGVSVLWKENDGGCKGVCNHVPTLEIEPKTFPEYCEGDSCYDEVLLQGLDQQIAGMKGKQGSKLVAFHLMGSHGPTYYRRYPAADRVFLPDCPRSDIENCSNEELVNTYDNTIRYTDKVLSQLIDKLKTLESQYNVGLVYLSDHGESLGAMGLYLHGTPYKFAPDDQTRVPLLTWFSPQLQRDRQLDQDCLRQEAGSKRFSHDNLFHSMLGIMDVQTQAYDGKLDLFKPCRAG
>NZ_CP038448.1|WP_042650224.1|3145572_3146787_-|ROK-family-protein
MTGGQIANVDLIKQVNSAVVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIRETSPQASTGGRRAISLTTIKHRFQFVSAKLGRGYLQLSLYDLDGKELDQHITQVTEIEQQPVVDMLLREIGAFIDANTERSRNLISIALTMPGLVNPESGMVIYTPTYQIRNLGLAKLLEHHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGTGSGIITKGQVFLGHNRNVGEIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKYITIQEVCKAAMAGDELARSVIENVGEHLGRAIAITVNLFNPQKVLIAGEITAAEEILIPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRSLLEGDLLQIIMEQK
>NZ_CP038448.1|WP_042650225.1|3146791_3147937_-|N-acetylglucosamine-6-phosphate-deacetylase
MYALTNCTLYTGSCVLTGHGVLIEGDKIVAISHLAELPAGIERIDLKGANLSAGFIDVQLNGCGGVMFNGHITTETLATMQAANLKSGTTSFLPTLITSPDADMKLAVAVTRDYMAAHPNEVLGVHLEGPYTNLKRKGIHPAEQIRQPVDEMIDFFCANSDAIAKITLAPERNKPEHIRRLVEAGILVSAGHTAASYDQAMAGFDNGMRFATHLYNAMTPTLNGREPGVVGAIYDRKDVYAGVIVDGHHVHWANVRLAHRILGEKLVLVTDATAAAGAPEGFEQFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENLVKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQAFTVCGTVVNGHYTTQ
>NZ_CP038448.1|WP_005325685.1|3147946_3148747_-|glucosamine-6-phosphate-deaminase
MRLIPLKSASQVGLWSARYIVDRINAFKPTSDRPFVLGLPTGGTPLTTYKRLIELHQAGEVSFQNVVTFNMDEYVGLPKEHPESYHSFMHNNFFNQVDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLASRTRVKTLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHAKALALQAAVEGCVNHMWTISTLQLHPKGMMVCDEPSTMELKVKTVRYFQQLEAANIDRL
>NZ_CP038448.1|WP_042650226.1|3149018_3150473_+|PTS-transporter-subunit-EIIC
MNILGYLQKIGRALMVPVAVLPAAAILMGIGYWIDPNGWGGESALAAFLIKAGAAIIDKMAILFAVGVAYGMSKDKDGSAALAGLVGYLVVTTLLSPGAVSQIQQIPLDQVPAAFGKIENQFIGILTGVIAAELYNRFSGVELHKALAFFSGRRLVPIVTSVVMIVVSFILMAVWPIIYGGLVSFGESIVSMGSTGAGIYAFFNRLLIPVGLHHALNSVFWFDVAGINDIPNFLGGQSSIDAGKAVVGVTGMYQAGFFPIMMFGLPGAALAIYHSAKKENKEKVASIMIAAAFAAFFTGVTEPLEFSFMFVAPVLYVIHALLTGLSVFIASSMHWISGFGFSAGFVDMFIQSRNPLATQWYMLLVQGLVFFGLYYAIFRAVIVKFNLKTPGREDDEAVQVQAQTTDRTELARQYLEVLGGQDNLVTIDACITRLRLTLKDRSIVDERKLKALGAAGVVKLGEQNLQVILGPLAEIIAGEMKALR
>NZ_CP038448.1|WP_042650227.1|3150595_3153259_+|carbohydate-binding-domain-containing-protein
MNLKHSLLAIAMSTVFVSQVQAADAAKQAVVDSLASNLVVKYEVVTNDGAGAGLDCQALGSEWASCGVAKLHLTNTGADVTSKDWSIYVSSIRRIQRVDNDQFTITHLTGDLYRLTPTEKFQGFAKDATVEVPLVVEYWVLFESDIMPNWYVASEGAEPKVLASMSNIDDATTYEKPMPADGWKRTKDDNNILMNSETRFAANQTSTLLPAGKIDDQILPTPMKQVVKAGPQVDFSTIKLNALDLPSDRAEAIKAQLTKLGVTLSDTGYPVTIKLGSKLKQAEGYDMTIGAKGTVVQGHDIDGAFWGAQSLISLLGVDDKLVSQMSVEDAPRFEYRGMQTDVARHFRSPETMKRLVDQMSAMKLNVLHLGLTNDEGWRIEIPGLPELTEVGSQRCHDESETKCLMPQLGSGPTNDNQGSGFYSKADYIDLVRYAKARGVTVIPEINMPAHARAAVVSMEARYKRLLAEGKETEANQFRLTDPDDTSNVTSVQFYDKMSFINPCQPGAATFVAKVMDEVAQMHQAAGQPLTAWHYGGDEAKNIMQGGGYQDPAVTKKEELVAWKGNVDSSKQDKPFGKSPLCQKMIDDGKIKDVAELPVHFAKEVSEMVKGHGFSTLQAWEDGLKYATDASVFATDKTRVNFWETLYWGGFNEAMKWAHKGYDVVLSNPDYLYFDFPNEVHPAERGYYWATRFNDTRKVFAFAPENLPQNAETSVDRDGNAFVAKGDQDPVKFKGISGQQWSETVRTDAQYEYMVYPRIFSVAERAWHKGGFELDYVKGREFSGTTKHVNKATLNKEWNQFANLLGQRVLPKLDQAGVEYRLSVPGAKVVNGKLEANVDLPGLPIQYSLDGTTWTAYDAAAKPSVNGKVWLRTTSFDGKRTSRVTELN
>NZ_CP038448.1|WP_005325679.1|3153598_3155260_+|glutamine--tRNA-ligase
MSEASSPTNFIRQIIDEDLASGKHKSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGQCNLRFDDTNPAKEDIEFVESIKQDVQWLGFQWSGEICYSSDYFDKLHGYAIELIEKGLAYVDELSPEQMREYRGTLTAPGKNSPFRDRSVEENLALFAKMKSGEMAEGSACLRAKIDMASPFMVMRDPVIYRIKFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIDCHPRQYEFSRLNLEYTVMSKRKLNLLVTEGHVSGWDDPRMLTVSGLRRRGYTPASIREFCQRIGVTKQDNIVEMSMLEACIRDDLNENAPRAMAVLHPVKVVIENLAADEVLTAPAHPSNAEMGTRELNFTREIFIDEADFKEEANKQFKRLVLGKEVRLRNAYVIKAERVEKDADGKVTCIYCSYDPETLGKDPADGRKVKGVIHWVSATHSLPAEIRLYDRLFKMPNPGAEDDFEAALNPDSLVIIAGARVEASLKDAKPEFAYQFEREGYFCADNKLSSPEHLVFNRTVALRDVWGKAEA
>NZ_CP038448.1|WP_005325677.1|3155377_3155806_-|ferric-iron-uptake-transcriptional-regulator
MADNNQALKKAGLKITLPRVKILEILQQPDCQHTSAEDLYKRLIDQGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELATQEHHDHLVCLDCGKVIEFSDEVIEQRQRDIAKHHNIRLTNHSLYLYGHCVNGDCKHDE
>NZ_CP038448.1|WP_042650228.1|3156050_3156551_+|DUF4442-domain-containing-protein
MDWLFDNAAWVRHALNAWPPFWGAGIKIETLSPDFRFCRVTLKSRWWNKNANRTQFGGSMFAMTDPIYPLMLMGHFKNRYYVWDKAGSINFIKPGKGMLVAEFNLTDAKLASIVAATEGGNKHFPEFEVQVQDKRGELVAQVRRTLYVKSKPEHRTPGQAASTMKE
>NZ_CP038448.1|WP_005325673.1|3156597_3157122_-|flavodoxin-FldA
MASVGLFFGSDTGNTEAVAKMIQKELGKQLIEVRDIAKSSKADIDSFDLLMFGIPTWYYGEAQADWDDFFPELEEIDFNNKLVAIFGCGDQEDYSEYFLDAMGTLRDIVEAKGAIIIGHWPTASYEFEASKALVDDKHFVGLGIDEDRQPELTAERVKGWCKQLHEEMCLSELE

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Crispr_ID: NZ_CP038448_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_6

3428702-3428805

Orphan

Consensus_repeat	Method
TATGTCGAGGAGGCGGTCAGCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_6

>merge|NZ_CP038448|6|3428702-3428805|CRISPRCasFinder
TATGTCGAGGAGGCGGTCAGCCGCCTCGAGCGACTGGTGTAGTCGCGAACCTTCCTGGGTTCCGGGAGGAGAGTCTGCGTTATGCCGAGGAGGCGGTCAGCCGC

>NZ_CP038448|6|5|3428702-3428805|CRISPRCasFinder
TATGTCGAGGAGGCGGTCAGCCGC	CTCGAGCGACTGGTGTAGTCGCGAACCTTCCTGGGTTCCGGGAGGAGAGTCTGCGT
TATGCCGAGGAGGCGGTCAGCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_171269626.1\|3428937_3430746_+\|M3-family-oligoendopeptidase	unknown	unknown	gnl\|CDD\|341070
NZ_CP038448.1\|WP_005331601.1\|3435463_3435781_+\|heavy-metal-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|179490
NZ_CP038448.1\|WP_171269617.1\|3419123_3419720_+\|penicillin-binding-protein-activator-LpoB	unknown	unknown	gnl\|CDD\|274269
NZ_CP038448.1\|WP_042648302.1\|3439809_3440904_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270700
NZ_CP038448.1\|WP_171269627.1\|3431570_3432863_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP038448.1\|WP_171269624.1\|3425876_3426791_+\|DUF808-domain-containing-protein	unknown	unknown	gnl\|CDD\|377542
NZ_CP038448.1\|WP_041205436.1\|3418725_3419124_+\|YcfL-family-protein	unknown	unknown	gnl\|CDD\|369276
NZ_CP038448.1\|WP_171269616.1\|3416888_3417239_+\|purine-nucleoside-phosphoramidase	unknown	unknown	gnl\|CDD\|182648
NZ_CP038448.1\|WP_171269628.1\|3432989_3433955_+\|IS1595-family-transposase	unknown	unknown	gnl\|CDD\|372298
NZ_CP038448.1\|WP_171269621.1\|3422200_3424003_+\|protein-translocase-subunit-SecD	unknown	unknown	gnl\|CDD\|183831
NZ_CP038448.1\|WP_171269622.1\|3424103_3425018_+\|protein-translocase-subunit-SecF	unknown	unknown	gnl\|CDD\|237275
NZ_CP038448.1\|WP_171269630.1\|3437297_3439559_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|293739
NZ_CP038448.1\|WP_171269618.1\|3419709_3420573_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|270700
NZ_CP038448.1\|WP_171269629.1\|3435941_3436952_+\|LD-carboxypeptidase	unknown	unknown	gnl\|CDD\|132883
NZ_CP038448.1\|WP_171269619.1\|3420626_3421487_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_171269623.1\|3425083_3425686_-\|DUF924-domain-containing-protein	unknown	unknown	gnl\|CDD\|377592
NZ_CP038448.1\|WP_171269620.1\|3421555_3422053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_005331594.1\|3430956_3431496_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|179896
NZ_CP038448.1\|WP_042650017.1\|3434018_3435062_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NZ_CP038448.1\|WP_005327565.1\|3441040_3442393_-\|lysine-sensitive-aspartokinase-3	unknown	unknown	gnl\|CDD\|236376

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_171269626.1\|3428937_3430746_+\|M3-family-oligoendopeptidase	gnl\|CDD\|341070	cd09607, M3B_PepF, Peptidase family M3B, oligopeptidase F (PepF). Peptidase family M3B Oligopeptidase F (PepF; Pz-peptidase B; EC 3.4.24.-) is mostly bacterial and is similar to oligoendopeptidase F from Lactococcus lactis. This enzyme hydrolyzes peptides containing between 7 and 17 amino acids with fairly broad specificity. The PepF gene is duplicated in L. lactis on the plasmid that bears it, while a shortened second copy is found in Bacillus subtilis. Most bacterial PepFs are cytoplasmic endopeptidases; however, the Bacillus amyloliquefaciens PepF oligopeptidase is a secreted protein and may facilitate the process of sporulation. Specifically, the yjbG gene encoding the homolog of the PepF1 and PepF2 oligoendopeptidases of Lactococcus lactis has been identified in Bacillus subtilis as an inhibitor of sporulation initiation when over-expressed from a multicopy plasmid.	0
NZ_CP038448.1\|WP_005331601.1\|3435463_3435781_+\|heavy-metal-binding-domain-containing-protein	gnl\|CDD\|179490	PRK02877, PRK02877, hypothetical protein; Provisional.	1.8129e-60
NZ_CP038448.1\|WP_171269617.1\|3419123_3419720_+\|penicillin-binding-protein-activator-LpoB	gnl\|CDD\|274269	TIGR02722, Penicillin-binding_protein_activator_LpoB, uncharacterized proteobacterial lipoprotein. Members of this protein family are restricted to the Proteobacteria, and all are predicted lipoproteins. In genomes that contain the thiK gene for the salvage enzyme thiamin kinase, the member of this family is encoded nearby. [Cell envelope, Other].	6.4369e-67
NZ_CP038448.1\|WP_042648302.1\|3439809_3440904_+\|hypothetical-protein	gnl\|CDD\|270700	cd05151, ChoK-like, Choline Kinase and similar proteins. This subfamily is composed of bacterial and eukaryotic choline kinases, as well as eukaryotic ethanolamine kinase. ChoK catalyzes the transfer of the gamma-phosphoryl group from ATP (or CTP) to its substrate, choline, producing phosphorylcholine (PCho), a precursor to the biosynthesis of two major membrane phospholipids, phosphatidylcholine (PC), and sphingomyelin (SM). Although choline is the preferred substrate, ChoK also shows substantial activity towards ethanolamine and its N-methylated derivatives. Bacterial ChoK is also referred to as licA protein. ETNK catalyzes the transfer of the gamma-phosphoryl group from CTP to ethanolamine (Etn), the first step in the CDP-Etn pathway for the formation of the major phospholipid, phosphatidylethanolamine (PtdEtn). Unlike ChoK, ETNK shows specific activity for its substrate and displays negligible activity towards N-methylated derivatives of Etn. ChoK plays an important role in cell signaling pathways and the regulation of cell growth. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	0.00185796
NZ_CP038448.1\|WP_171269627.1\|3431570_3432863_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.39649e-161
NZ_CP038448.1\|WP_171269624.1\|3425876_3426791_+\|DUF808-domain-containing-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	1.12625e-143
NZ_CP038448.1\|WP_041205436.1\|3418725_3419124_+\|YcfL-family-protein	gnl\|CDD\|369276	pfam07233, DUF1425, Protein of unknown function (DUF1425). This family consists of several hypothetical bacterial proteins of around 125 residues in length. Several members of this family are described as putative lipoproteins and are often known as YcfL. The function of this family is unknown.	2.36068e-30
NZ_CP038448.1\|WP_171269616.1\|3416888_3417239_+\|purine-nucleoside-phosphoramidase	gnl\|CDD\|182648	PRK10687, PRK10687, purine nucleoside phosphoramidase; Provisional.	2.84762e-70
NZ_CP038448.1\|WP_171269628.1\|3432989_3433955_+\|IS1595-family-transposase	gnl\|CDD\|372298	pfam12762, DDE_Tnp_IS1595, ISXO2-like transposase domain. This domain probably functions as an integrase that is found in a wide variety of transposases, including ISXO2.	1.18633e-10
NZ_CP038448.1\|WP_171269621.1\|3422200_3424003_+\|protein-translocase-subunit-SecD	gnl\|CDD\|183831	PRK12933, secD, protein translocase subunit SecD.	0
NZ_CP038448.1\|WP_171269630.1\|3437297_3439559_-\|LTA-synthase-family-protein	gnl\|CDD\|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	2.20782e-40
NZ_CP038448.1\|WP_171269618.1\|3419709_3420573_+\|phosphotransferase	gnl\|CDD\|270700	cd05151, ChoK-like, Choline Kinase and similar proteins. This subfamily is composed of bacterial and eukaryotic choline kinases, as well as eukaryotic ethanolamine kinase. ChoK catalyzes the transfer of the gamma-phosphoryl group from ATP (or CTP) to its substrate, choline, producing phosphorylcholine (PCho), a precursor to the biosynthesis of two major membrane phospholipids, phosphatidylcholine (PC), and sphingomyelin (SM). Although choline is the preferred substrate, ChoK also shows substantial activity towards ethanolamine and its N-methylated derivatives. Bacterial ChoK is also referred to as licA protein. ETNK catalyzes the transfer of the gamma-phosphoryl group from CTP to ethanolamine (Etn), the first step in the CDP-Etn pathway for the formation of the major phospholipid, phosphatidylethanolamine (PtdEtn). Unlike ChoK, ETNK shows specific activity for its substrate and displays negligible activity towards N-methylated derivatives of Etn. ChoK plays an important role in cell signaling pathways and the regulation of cell growth. The ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.05057e-32
NZ_CP038448.1\|WP_171269629.1\|3435941_3436952_+\|LD-carboxypeptidase	gnl\|CDD\|132883	cd07062, Peptidase_S66_mccF_like, Microcin C7 self-immunity protein determines resistance to exogenous microcin C7. Microcin C7 self-immunity protein (mccF): MccF, a homolog of the LD-carboxypeptidase family, mediates resistance against exogenously added microcin C7 (MccC7), a ribosomally-encoded peptide antibiotic that contains a phosphoramidate linkage to adenosine monophosphate at its C-terminus. The plasmid-encoded mccF gene is transcribed in the opposite direction to the other five genes (mccA-E) and is required for the full expression of immunity but not for production. The catalytic triad residues (Ser, His, Glu) of LD-carboxypeptidase are also conserved in MccF, strongly suggesting that MccF shares the hydrolytic activity with LD-carboxypeptidases. Substrates of MccF have not been deduced, but could likely be microcin C7 precursors. The possible role of MccF is to defend producer cells against exogenous microcin from re-entering after having been exported. It is suggested that MccF is involved in microcin degradation or sequestration in the periplasm.	4.19023e-127
NZ_CP038448.1\|WP_171269622.1\|3424103_3425018_+\|protein-translocase-subunit-SecF	gnl\|CDD\|237275	PRK13022, secF, protein translocase subunit SecF.	1.04096e-91
NZ_CP038448.1\|WP_171269623.1\|3425083_3425686_-\|DUF924-domain-containing-protein	gnl\|CDD\|377592	pfam06041, DUF924, Bacterial protein of unknown function (DUF924). This family consists of several hypothetical bacterial proteins of unknown function. Structurally, this family resembles TPR-like repeats.	1.8602e-84
NZ_CP038448.1\|WP_005331594.1\|3430956_3431496_+\|alpha/beta-hydrolase	gnl\|CDD\|179896	PRK04940, PRK04940, hypothetical protein; Provisional.	6.83008e-139
NZ_CP038448.1\|WP_042650017.1\|3434018_3435062_+\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.40939e-38
NZ_CP038448.1\|WP_005327565.1\|3441040_3442393_-\|lysine-sensitive-aspartokinase-3	gnl\|CDD\|236376	PRK09084, PRK09084, aspartate kinase III; Validated.	0

>NZ_CP038448.1|WP_171269624.1|3425876_3426791_+|DUF808-domain-containing-protein
MAGASLLTLLDDIASVLDDVALMTKMAAKKTAGVLGDDLALNAEQVSGVRAERELPVVWKVAKGSFRNKLILVPAAIAISALIPWLITPLLMLGGAYLCFEGAEKLAHKFLPHDRGETASSVEALPDDLEAFEQQKVKGAIRTDFILSAEIIVIALGTVQGSSLGLQIAVVAGIALLMTVGVYGLVGLIVKLDDIGLHLLQKPDAGALRRAVGRGLLVTAPRLMHLLALVGTIAMFMVGGGILVHGWPFAHHLIEGVAASLAPLTGGAVLAAVTPTLLSALVGVVAGLLLVLTMTLVGKLTPAK
>NZ_CP038448.1|WP_171269623.1|3425083_3425686_-|DUF924-domain-containing-protein
MQPWQPLLDFWFGDDSGDAPRAVRQAPLWWGKSSETDALLTHRFGELAQGAAEGELAHWAEVPVGRLALILLLDQLPRNLHRGTPAAFAQDAKARDLCLKGLSLGADKALSPLARVFFYLPLEHAESREQQARSVALFEALAAEQGDGPARETFEGFADFARRHQVIVQRFGRFPHRNAILGRTSTPEEAEFLRQPGSGF
>NZ_CP038448.1|WP_171269622.1|3424103_3425018_+|protein-translocase-subunit-SecF
MLRMIIAMGLTRWRYIGMWASVLLTVASIAVLAINGLSLGLDFTGGILLEFRIQTLKEAHELNALLSAPLAGAVELHGAGVPGEWLIKLPPHELPWAAEDLATMLGQQLALPVELLRTTIVGPQVGAELFQQGMLAVLVASLAISAYLAVRFEWRQAIGILVSVLHDGLVALGLLALFNIEFDLNVIAGLMAVIGYSLNDSIVISDRLRDLLGSRTQMGIHDCSDVAIKATFSRTMITSGTTLFTVGALLLFGGDALFGFSFTLFAGILVGTISSITVASTVQELLGLSPQAYQKKEEELVEAA
>NZ_CP038448.1|WP_171269621.1|3422200_3424003_+|protein-translocase-subunit-SecD
MRKKSHTILNRMSLWQYALLLLMLLTFTFYSLPTFFGEQPSLGLHGQSRLSGAQQRLLQEHQIAPQLQIEQKERVELVFATQAEQQRAKQLLEQQGVDSAALTLEFHSNAPTWISRLGADPIKLGLDLRGGSQLLIGVDVDFVIDNQTKNLVDTLRTRFREANLRGASVMRTAQGSVAVTLPDVAGQEGWLNIIKESAGTRQDQWTLSRSGNELRLVLSDAERTLLVNNAVTQNLSILKKRINELGIVEASVQRQGQDGIRIELPGVHNPKQAKEVIGATASLAFYEAKADSRFFMADRNGQAVGLARNPVLSGEHIVDARANMGEMGQPQVNIVLDTLGGSKMNQFSRQHVGKPMATVFTEYKTNAEGKLRARSEVINVATIQTALGNQFRITGIGSLPEAQELAMLLRAGALTAPLKILEERSIGPTLGLQNIEAGFTALAFGMAGMMLFMMAWYRKFGWVAITALIANLLMQVGMLAVLPGAVLTLPGIAGLVLTVGMAVDTHVLIFERIKDRLREGGSLANAIDFGYRSAFRTIFDANITTLICAVVLYAIGSGPLQGFSITLILGLISSMVTGIWGTRAIINPLWGNSRAKLLRV
>NZ_CP038448.1|WP_171269620.1|3421555_3422053_+|hypothetical-protein
MVVCPFYYSGINFLSLLDKVKLAAMTLLIALTLLLSTVSVEGLKVPASQHAAQLMGEAADSTDGARIQHGASDSDDGVVKFVGSHQNHLLRLEHSLSRDHQPGRVVYELVMSWAQQGILLLLCGLLLYAALCYPRTSFRDHFASIHRRRLQRRHLQYRFSQSLLA
>NZ_CP038448.1|WP_171269619.1|3420626_3421487_+|hypothetical-protein
MVTRFSWRQPRSWSLLLLCLLLTGCATRVIYYWLDSAIVWQLDDYFSLDRSQKTLLDREVKGLMAWHRQHELPIYARDLDALAKAVASPMTPAQVTLHLDRTQASLTRTLENAIPRTVRLASTLTDAQVARFMTDRVKRQQERQHDFATESKTQMLKEFREKMNERLVFWIGKVKPAQEPLIAQWAEWQYEMMPPWLEFQEAWTKELARLMKQRQDPDFGKELTRLLQQGDGLMDGRFTGYTDQSRQRTIQWLSDLSQSLDLSQRAHLYTLLKDYAEDFEAMIRSR
>NZ_CP038448.1|WP_171269618.1|3419709_3420573_+|phosphotransferase
MAGEATRQQGDLAELTLLASLPAPWNQGRLEPLASGLTNGNYRLHLPSGQRAFLRRGHPDPVRLGIDRATEWQLYQGAVGEGLALPCYHSEPASGLMLLAWCDEPNWAAAPPPLAAQPPLLAAVLRRLHRLPLPAVVMAVRAHSAGYRDRLARVPAWLPALERALLASREPDDCWLPCHHDLNPANLLGHRPWVIDWEYGAAGHPGFELASIQRTHGWSDELRCQLESCYLEGRGGAHKLLNTKGFQAEAFLPWVDYIGLLWALLMAEQQPGPDYQALIDMNRQRLE
>NZ_CP038448.1|WP_171269617.1|3419123_3419720_+|penicillin-binding-protein-activator-LpoB
MRMNHALLILTGTLLLGGCSSTTVSYGDATETETVTVDYGSSDLQAIADKMADSMLASPATSEITAGGRPVMFMDSIRNKTSEHIDTEAITDTLRTKLLRSGKFRFVDMSKVSAVKQQLEHQQGSGMVDPATMVRLGKQTGARYMVYGNLASIVKDNGKVKDVYYQMTMNLMDLENGELLWADQKEIRKQAKTSTFGW
>NZ_CP038448.1|WP_041205436.1|3418725_3419124_+|YcfL-family-protein
MKAHGLALGLVLLLAGCATNTSGVALYGAAGAAAVQEQHQDVNVTLTELSRREQNGLLQVNVAAASTQRGDNRLQYLFYWYDDAGQEVASDGRGWTPLKLHGYQTRTLSALAPSPAARGYRIYVREVIEESN
>NZ_CP038448.1|WP_171269616.1|3416888_3417239_+|purine-nucleoside-phosphoramidase
MAQETIFSKIIRKEIPADILYQDDLVTAFRDIQPKAKTHILIVPNVLIPTVNDVEVDHELALGRMFTVARKLAAEAGIAEDGYRLIMNCNRHGGQEVYHIHLHLVGGQPLGPLLSL
>NZ_CP038448.1|WP_171269626.1|3428937_3430746_+|M3-family-oligoendopeptidase
MQQRVYPQQWQNQHIYPSLDSCVLEADMSLARASLAELSGFIEGLVGVQGNQPARQDFLREVRLRARRIREIGWNIAVLAACKGSQDARDPLAKQLASRARALNADLFKTLAPIEDLMLGLPEAEFEQLMQDPLLGEEEYRLRHERRLQDQRLPVEAEQLVIGLGTDGLHAWGNLYNDLVGKIRLVIDGREMGLAEASNLLSSPDRALRKEAFDAISAGWEGEQETVAAILNALNGWRLELSRQRGKVRTLDALDLSCHQSHIERATLDTLMQETWQARHLGQRALGLMARGLGIEELGPEDLFAPPPASSHRSIPFEEAIEIIALAFTGFDPEMGEFARMMAERGWIDAAPTPNRRTGAYCTKFADPVEPRVFITYAGTMDNVITLAHELGHAWHNWLIRDLPMSQRSYPMTLAETASIFAETLVRSALFEQARSAEERQAIAWAEADGAATFLVNIPARFAFEQTLVAEREQGYVSSARLKALTDEAWGCWYEESLCRYHPMFWAAKAHFSIAGFGFYNYPYLFGYLFSLGVYQQLISRQAAGEQDVAQAYRALLRDTGRMSAEELVVKHLGQDIREAAFWQGSLALVAAAVDRFEQTLS
>NZ_CP038448.1|WP_005331594.1|3430956_3431496_+|alpha/beta-hydrolase
MIIYLHGFDATSPGNHEKVLQLQFIDDDVRFVHYSTVHPRHDMSHLLKEVKKQLDMSTDPKPLICGVGLGGYWSERIGFLCGIKQVVFNPNLHPEENMQGKIDRPEEYEDIGTKCVTEFRNKNSGNCLCILSVQDEIRDNRDTERELKNYYDIVWDERETHKFKNISHHLQRMKAFKEA
>NZ_CP038448.1|WP_171269627.1|3431570_3432863_+|NAD(P)/FAD-dependent-oxidoreductase
MMNIVVVGGGAGGLELATSLGRKLGKKNKARITLVDRNRTHLWKPLLHEVATGSMDAGIDALSYQSHAKNHGFEFQLGSLTDIKRDEKRIVLAPIHDDSGALVVNERELAYDVLVMAIGSVSNDFNTKGIKDHCIFLDSPSQAHRFYNSMMNRFLQFATEYQPGDKVKIAIVGGGATGVELSAELYNAVEQLYAYGFKNLTTDSLKVTLVEAGPRILPALPERISGSAHQELVKLGVDVRTATMITEATAEGLHTKDGELIEADLMVWAAGIKAPDFMKEIAGLETNRINQLVVKETLQTSRDENIFVIGDCAACPQPDGKFVPPRAQSAHQMATQAFKNILAKMNGGELKPYLYHDHGSLVSLSRFSTVGSLMGNLMRGSMMVEGYIARIVYISLYRMHQVALHGYIKTGLIMLVGRINRVLRPSMKLH
>NZ_CP038448.1|WP_171269628.1|3432989_3433955_+|IS1595-family-transposase
MDTQAFQHLLTLFPQLSVRQRHIAQRELQQPSLPSRINALLPDCPACPHCHAQPDQLAPWGWTRGLRRYRCKQCLRTCSTLTKTPLARLRKSQCWQAYAQVLIDGLTVRAAARRCGVSKNTAFLWRHRFLRAMAEHRADHEGGIVEVDETFFLESFKGQHVWSRPARQRGGKGRTRGTGPDYIPVVVVQDREGHLADFQLEQLDARHVKAVLAPLVDKDAVLCSDGAGVYASFARSQGLSHQVLHNRVGQRVISGAYHIQHVNGYHRRLKEWMERFHGVATSYLKHYLGWRRMLERYQRGIDVRCCLHEALGRPMQHVIGT
>NZ_CP038448.1|WP_042650017.1|3434018_3435062_+|IS110-family-transposase
MTQSQIYIYGIDLGKNWFHLVAMDRMGHVLTKQKLTRSQLKQFISTTPPCRVAFEACPGSQYWGRLFQQAGFEPKIIPAQFVKPYLKSNKNDFNDATAIAEAGSRGTMRCVPLKSHEQLALQATHRVRQRFIIERTATVNQMRALLLEYGLTVPVGRKVFERALPAILEDAENGLPDFIRALVLRLRERWQQLDIQIDEMSLMLGQASSASSLCQKVSTVPGIGPIVSTALIAAIGNGSQFKKARDLSAWLGLVPRQYSTGGKSSLGGISKRGNNYLRQMVIQGAKALKIHMKRDKSSLGEWVARLEVGHHHHVVLIALANKIMRICWKVLTSGRDYRPYPNASAAV
>NZ_CP038448.1|WP_005331601.1|3435463_3435781_+|heavy-metal-binding-domain-containing-protein
MILSTTPTLEGKTIREYRGIVVGEAILGANIFKDLFAGIRDIIGGRSGAYEKELARAREIAFEELRERAAALGANAVVGIDIDYEVVGQNGSMLMVSISGTAVVV
>NZ_CP038448.1|WP_171269629.1|3435941_3436952_+|LD-carboxypeptidase
MTLLKPPGLRPGDTIGFFSPSSAATAWAPNRFARAKAYLAAQGVELKAGSLTGERDHWRSGSIAARAEELNALIRDPEVRAIMSVIGGSNSNALLPYLDYEALKRDPKIIIGYSDVTALLLGIHARTGLVTFYGPALVASFGELSPLVDETLAGFNQICQAGGAAVPHTVPTPTQWTDERLDWEQQTRAKQCLPNRLISVGSGRVRGRLIGGNLNTLAGIWGSPYMPPIARGDILLLEDSLHLAETVERSFAHLKLCGVFDRIGALVLGKHELFDSQGSGRRPLDILLEVVGEPTFPILAEFDCAHTHPMLTVPLGIEAELDLDRQTLTLCEPWLR
>NZ_CP038448.1|WP_171269630.1|3437297_3439559_-|LTA-synthase-family-protein
MNAPVCGHSPSLSQSLAGWLFGLLIALLLLTLALPLLNPAGLLGRAQPLILGPADQPIATLSRHSLLYKSDSRGLYLVVRSQWQLLKPLQEGDKVRVELLNDKGIRIDQLNQAVEKRQKCRQERCTLDLNSALRAPDDALDSRYQLRIGLLLADRPESAEYSQILQTLPERGFNLSYLMISLLLVLLMSAAVLRAMLPRLRRSYRSRIVGSLLLGNLTFVLLHGFVVFKLGEFLFWSGFRPEHYYLAWGSMVLGWSLCALAGFNLYMGLVFTALSGIGLLANFMKIAIYGVPLGGDDLGNLLALLHILLDQHPVLPVLAVLGFLFLCWRFALSRWILRTAAATAAFFALCVFATQTGNKLLGANIRYVDRAVNYHRDIIRAGPGLYLFNLVDEMLQSGNVFRYPLQINERTPELSQPARGQPPRFDLVIVLQYESLWLDWQGKICAPAPTLSLPAGVAQWHKTIHSPTTGGMTVLAEFEMNTGLPAGLLKQGVVPYYYLSAQVPGLARSAKQSGYQTLFAHPYVEKFWGRAKAIPALGYEERWFDTRFTTLEHKGLYISDDALIDHLIKRSEQDNRPLFAYAVTMQGHGPFDGDRYRAQQIDMACPDQSPAERQLLNTYYTGVVDAMASLERLLKTLDQSGKRYLVVAFGDHQPFLMSASKGIHGAKPPRDAAYQIPMMAFTRADDPLNLATQFAPVRQLYQMGQATRALLAGDLAPIEDKPLLHPVLGEEKGFDPSPLVPQIRASFRADALP
>NZ_CP038448.1|WP_042648302.1|3439809_3440904_+|hypothetical-protein
MNPKVAARQARLLQMLENNDEIRIGRERDCPLPLAQLLRLTEDHPDVVRVYGHGLTAEVFHLKVEGHHWCLKRCRPDSLVANVDGKTAFLTELERRREIESLRELHPTILSNVVCTSFGSARTGVLVSPWLRGEPVRRLNERNLAQMLAVEAELARWGWFDWDPSPGNLLDDGQQISVFDFGYMWPFDPLHEFNSNGLTDPEFHVPERLETRTLSGLWLDDADPLPLFRHWRGLCLAWAKGELQYLSREGASAPVLARMQGLVGEWSAALASDEALAANWWRDMYRSHRLDIQDDLSGKSCGPMTLRRLDWLEQAVRDHFPALAENLGPDEAGLSQAALLQRLGGLREQIRANLLPTPASQSMG
>NZ_CP038448.1|WP_005327565.1|3441040_3442393_-|lysine-sensitive-aspartokinase-3
MNPINVAKFGGTSVADAAAMNHCADVVLANPATRVVVLSASAGVTNLLVSLAQGELDEAGQDAQLARLTGIQQAILTALGNPGEVSALIHAQLGDIRTMARQACQHTDAELADRLIACGELMSTRLFTELLHQRGIKACWQDARQLLRTDSRFGKATVDLAATRTLCQATLGPLLGDSLVITQGFIGADADGRTTTLGRGGSDYSAALLAEALDAGSIEIWTDVPGIYTTDPRLVTRARPIPEISFVEAAEMATFGAKVLHPATLQPALRQDIPVFVGSARDPAAGGTWIRASTETCPLFRAVALRRQQVLVTLHSLNMFHAYGFLAEVFGILARHRISVDLITTSEVSVSLTLDHTGSQSNGEPILGDKVLAELGQLCKVEVETDFALVALIGNRMSEAAGVGSRVFDAIREHNIRMICYGASAHNLCFLVKESEAGNIVNRLHQELLD

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Crispr_ID: NZ_CP038448_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_7

3517907-3518024

Orphan

Consensus_repeat	Method
CCGCCGTGGCTTAACTGGATTTCTCTCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_7

>merge|NZ_CP038448|7|3517907-3518024|CRISPRCasFinder
CCGCCGTGGCTTAACTGGATTTCTCTCATCGTGATTGGATCTCCACAAGGTTGCCGAAACAGGCTGGTTCATCTCCACTCATCACCCGACCGCCGTGGCTTAACTGAATTTCTCTCAT

>NZ_CP038448|7|6|3517907-3518024|CRISPRCasFinder
CCGCCGTGGCTTAACTGGATTTCTCTCAT	CGTGATTGGATCTCCACAAGGTTGCCGAAACAGGCTGGTTCATCTCCACTCATCACCCGA
CCGCCGTGGCTTAACTGAATTTCTCTCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_171269670.1\|3515525_3516518_-\|hydrogenase-nickel-incorporation-protein-HypB	unknown	unknown	gnl\|CDD\|182479
NZ_CP038448.1\|WP_171269669.1\|3514566_3515208_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224049
NZ_CP038448.1\|WP_042648480.1\|3509749_3510256_+\|hydrogenase-2-assembly-chaperone	unknown	unknown	gnl\|CDD\|182480
NZ_CP038448.1\|WP_010674427.1\|3531243_3531606_+\|DUF2750-domain-containing-protein	unknown	unknown	gnl\|CDD\|378546
NZ_CP038448.1\|WP_042648479.1\|3509237_3509768_+\|HyaD/HybD-family-hydrogenase-maturation-endopeptidase	unknown	unknown	gnl\|CDD\|182481
NZ_CP038448.1\|WP_171269676.1\|3527445_3527838_+\|MAPEG-family-protein	unknown	unknown	gnl\|CDD\|226311
NZ_CP038448.1\|WP_171269668.1\|3513778_3514567_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224048
NZ_CP038448.1\|WP_171269667.1\|3512972_3513785_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_CP038448.1\|WP_025326665.1\|3522600_3523200_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NZ_CP038448.1\|WP_017784111.1\|3519126_3519378_-\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl\|CDD\|223375
NZ_CP038448.1\|WP_171269666.1\|3511972_3512983_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_CP038448.1\|WP_171269672.1\|3519383_3521801_-\|carbamoyltransferase-HypF	unknown	unknown	gnl\|CDD\|223146
NZ_CP038448.1\|WP_171269675.1\|3526406_3527381_+\|ferrochelatase	unknown	unknown	gnl\|CDD\|234585
NZ_CP038448.1\|WP_171269664.1\|3507534_3509238_+\|hydrogenase-2-large-subunit	unknown	unknown	gnl\|CDD\|182482
NZ_CP038448.1\|WP_171269984.1\|3529538_3531119_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP038448.1\|WP_171269674.1\|3525647_3526292_+\|adenylate-kinase	unknown	unknown	gnl\|CDD\|234711
NZ_CP038448.1\|WP_171269665.1\|3510371_3511988_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_CP038448.1\|WP_139459158.1\|3516519_3516861_-\|hydrogenase-maturation-nickel-metallochaperone-HypA	unknown	unknown	gnl\|CDD\|376468
NZ_CP038448.1\|WP_171269673.1\|3523481_3525395_+\|molecular-chaperone-HtpG	unknown	unknown	gnl\|CDD\|235366
NZ_CP038448.1\|WP_171269677.1\|3528024_3529329_+\|inosine/guanosine-kinase	unknown	unknown	gnl\|CDD\|185033

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_171269670.1\|3515525_3516518_-\|hydrogenase-nickel-incorporation-protein-HypB	gnl\|CDD\|182479	PRK10463, PRK10463, hydrogenase nickel incorporation protein HypB; Provisional.	1.81637e-145
NZ_CP038448.1\|WP_171269669.1\|3514566_3515208_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.15627e-68
NZ_CP038448.1\|WP_042648480.1\|3509749_3510256_+\|hydrogenase-2-assembly-chaperone	gnl\|CDD\|182480	PRK10465, PRK10465, hydrogenase-2 assembly chaperone.	1.88936e-86
NZ_CP038448.1\|WP_010674427.1\|3531243_3531606_+\|DUF2750-domain-containing-protein	gnl\|CDD\|378546	pfam11042, DUF2750, Protein of unknown function (DUF2750). This family is conserved in Proteobacteria. The function is not known.	3.8262e-36
NZ_CP038448.1\|WP_042648479.1\|3509237_3509768_+\|HyaD/HybD-family-hydrogenase-maturation-endopeptidase	gnl\|CDD\|182481	PRK10466, hybD, HyaD/HybD family hydrogenase maturation endopeptidase.	8.38389e-92
NZ_CP038448.1\|WP_171269676.1\|3527445_3527838_+\|MAPEG-family-protein	gnl\|CDD\|226311	COG3788, COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only].	2.45975e-22
NZ_CP038448.1\|WP_171269668.1\|3513778_3514567_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	9.13134e-64
NZ_CP038448.1\|WP_171269667.1\|3512972_3513785_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.57573e-55
NZ_CP038448.1\|WP_025326665.1\|3522600_3523200_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	2.645e-110
NZ_CP038448.1\|WP_017784111.1\|3519126_3519378_-\|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl\|CDD\|223375	COG0298, HypC, Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones].	2.76525e-28
NZ_CP038448.1\|WP_171269666.1\|3511972_3512983_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.42947e-99
NZ_CP038448.1\|WP_171269672.1\|3519383_3521801_-\|carbamoyltransferase-HypF	gnl\|CDD\|223146	COG0068, HypF, Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP038448.1\|WP_171269675.1\|3526406_3527381_+\|ferrochelatase	gnl\|CDD\|234585	PRK00035, hemH, ferrochelatase; Reviewed.	6.76778e-163
NZ_CP038448.1\|WP_171269664.1\|3507534_3509238_+\|hydrogenase-2-large-subunit	gnl\|CDD\|182482	PRK10467, PRK10467, hydrogenase 2 large subunit; Provisional.	0
NZ_CP038448.1\|WP_171269984.1\|3529538_3531119_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	2.11989e-66
NZ_CP038448.1\|WP_171269674.1\|3525647_3526292_+\|adenylate-kinase	gnl\|CDD\|234711	PRK00279, adk, adenylate kinase; Reviewed.	4.63302e-140
NZ_CP038448.1\|WP_171269665.1\|3510371_3511988_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP038448.1\|WP_139459158.1\|3516519_3516861_-\|hydrogenase-maturation-nickel-metallochaperone-HypA	gnl\|CDD\|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	6.186e-46
NZ_CP038448.1\|WP_171269673.1\|3523481_3525395_+\|molecular-chaperone-HtpG	gnl\|CDD\|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NZ_CP038448.1\|WP_171269677.1\|3528024_3529329_+\|inosine/guanosine-kinase	gnl\|CDD\|185033	PRK15074, PRK15074, inosine/guanosine kinase; Provisional.	0

>NZ_CP038448.1|WP_139459158.1|3516519_3516861_-|hydrogenase-maturation-nickel-metallochaperone-HypA
MHEMSLAMAAIDLAAEQATQRGFNKVTALWLEVGSFSCVDPDTIAFCFEAAAKGTAVEGAQLHFLHQAAEAWCYDCNQTVTLTERGQACPECGGYKLRVAQGDSLRITDIEVS
>NZ_CP038448.1|WP_171269670.1|3515525_3516518_-|hydrogenase-nickel-incorporation-protein-HypB
MCSVCGCGQARIAGHEHDHEHHHEHDNEHHHEHGHEHGHHHHDHEQSALRTLIIHHHYHHQGDVHHHYHGVRAPMGAEGHDHPHEHEHEHEHEHEHLQADLHYGKGEAGLSVPGMGQRQLIAIEMDVLAKNNALAAHNREHFDEAAQLVLNLVSSPGSGKTTLLCETLRQLADKRPCAVIEGDQQTSADADRIRATGVPAVQINTGKGCHLDAKMVHDACHQLPANEGGILFIENVGNLVCPASFDLGEKYKVAILSVTEGEEKPLKYPDMFAAAQLMVINKIDLLPYVSFDVARCIENAKRVNPYIQVIQVSATTGEGMDAWLNWLATA
>NZ_CP038448.1|WP_171269669.1|3514566_3515208_+|ATP-binding-cassette-domain-containing-protein
MLEVRDLTIAQGECPLWQGLSLAVKAGERLGISAPSGYGKTTLGRVLAGWQPVRGSGGILLDGQPVPEQVKGYNPIQLVPQHPELTFNPYRTTGQALWDVWRPDDAMLARFMVKPEWLERKPGQLSGGELARIALLRALDPRTRLLIADEVTAQLDPQIQRQLWQELMVECEQRGLGMVIFSHQQALLRQICHRVLRFGEVPGAQEQLARSVA
>NZ_CP038448.1|WP_171269668.1|3513778_3514567_+|ATP-binding-cassette-domain-containing-protein
MLSFDHVTIEAAHYSWLGRRRWQPLLTDISLQLAPGEIVALVGGSGEGKSLLLQSALTLLPDNLRMRGTISLDGTPLCDASRARLRGHTLCYVPQGVSALNPLLTVERQLGRAARLCGQNGSRERLGEQLLRYQLPATTLDSYPRQLSGGMAKRILACTAALGGARYILADEITAWLDEGLACQLLSQLRELANQGSGILWVTHDLALAARFADRIVALHQGQVSDTLSCHHLRQGQGSEMLRAHWQALPEFNSLFSAPEVS
>NZ_CP038448.1|WP_171269667.1|3512972_3513785_+|ABC-transporter-permease
MLFNPLPSILRLVFALLGLALLAAYGWSLSHQDVPMDLLARQQPPSLTHWFGTDQMGRDLWLRAFQGTLTSLELGLGTALCSGLLAMVAASVSLIHPRCDVAVRMVIDAMLALPHMLLLILICFTVGGGMRGVILAVALTHWPKPALILCAEARRIASSDYVVLARCQGMGALRRWRTHLLPGLLPQWFIGTLLMFPHAVLHSAALSFLGFGLAAHEASLGLLLADALRYLAGGGWWLALFPGLMLLTLVLLFDQATRALQQLWFGSEQC
>NZ_CP038448.1|WP_171269666.1|3511972_3512983_+|ABC-transporter-permease
MDVPLSSPLSHSGYLLLKALLRLAGLLCLVSVATFVLLSYSPIDPIKAYIGNDLLHVPPEQYARIAARWGLDQPLWLRYWHWFTQVLQGDLGYSMLYNAPVGEVIGQRFAASFLLLAGAWLLSGFFGILLGLCAGRYLNRWPDRLICRFAYLLASLPTFWVGLLLLALFAVHWPLLPVCCAWTPGLSADEVDWAMRLRHLLLPVTTLALLGVGNIALHTRGRVAEVLDSDFIRYARAQGDGGWPMLRFHVLRHALTPALCLQFASLGELIGGSLLAEKVFSYPGLGQATVDAGLRGDIPLLMGIVLFCTLLVFIGNTVASLLLARINRGWEGEHAV
>NZ_CP038448.1|WP_171269665.1|3510371_3511988_+|ABC-transporter-substrate-binding-protein
MTLRTYDARAAGALLALLLGASPLAQAALATETTPVTQPVPAELKLAIGAEPTEGFDPLLGWSHGSYLLLHSPLLKQNADLGWQNVLTQAVAPNKDGKGWLITLKPGLKFSNGAPLTAEDVAFTYNSAAKGGGKIDMGNFVSAKVVSPTDVAISLSVPQSTFVNVLGSLGIVSKQDYDPKRYAREPVGAGPYRLVSFLPGQQLVVEANPYYAGGNNDFKRLVFVFIDEESAYAAAQSSQLDVVRIAPSLAPTVPDSLRLWVRPSVENRGIVFPIPPAGSKDAKGYPIGNDVTSDVAVRRAINYAIDRKLLADQLLEGHAIPAYSAVEGLPWLNKATAFKDGDAAHANALLDQAGWKRGSDGIRHKGDLRAAFTLWYTSGDSTRRDLAEAVRAMLNSSGLEVSLKSGSWEQVEREMHANPVLMGWGSLDPMELYHHYQSGSGGVEFYNPGYYSNPVVDGHLKQALDATDWQAAVPFWQQVEWDGKTGAGVQGDAAWAWLLNVQHTYLANRCIDLGKGAPEIHGSWSLLNNLQDWRWTCR
>NZ_CP038448.1|WP_042648480.1|3509749_3510256_+|hydrogenase-2-assembly-chaperone
MAQSHLSEVDAVQEFAGFTSDPAPLLVAQYERIAREEMQALPFYHATMPIVAECVLFEGQWLGCVLTPWMLSVVVLPGPDQLWPVRSSSDRLALPLPCGNMTFMVGELPETGQLLACSLMSPLDPHLGAEQGRSLVSSTLKMLHSLPVQQGEGRVDLGRRRLFGARGR
>NZ_CP038448.1|WP_042648479.1|3509237_3509768_+|HyaD/HybD-family-hydrogenase-maturation-endopeptidase
MNTLILGVGNLLLSDEAVGVRIVEGLEREYRFAPGIELLDGGTAGMELLEAMASRDHIILVDAVRSGNPPGTVVTLKDEEVPTLFGRKISPHQLGLADVLSALHMTGESPKRLTLIGVEPESLEPRIGLTPLVAAAMGEATDRILTLLAAVGAPAIALSEQEKAEQAREGLWRSPI
>NZ_CP038448.1|WP_171269664.1|3507534_3509238_+|hydrogenase-2-large-subunit
MSQRITIDPITRIEGHLRIDCEIEGGIVTKAWSSGTMWRGMEEIVKGNDPRDAWMIVQRICGVCTSIHAIASVRAVENAIGAKVPVNAQFIRNLIIAAHNIHDHIVHFYQLSALDWVDITAALEANPQKAADILKGVSTWSLNSAEELAKVQEKIRALVASGQLGIFANGYWGHKAMKLSPEVNLIAVAHYLQALECQRDANRIVAILGGKSPHIQNLAVGGVANPINLDAPSVLNLERLMYVKSFIDRLGEFIEQVYKVDAAIIAAHYPEWLSLGQGAKHYLSVPELPTDGDGGSFLMPGGYIENGDLAGYRPIESHQDAWLMDGIAESNKHAWYKDDAPLKPWEGKTEPNYTGWQDDGKYSWVKSPTFYGKVVEVGPLADLLVKLAAKHPETVAHFDQLNGLYKTLTGSAIKTEQLHSTLGRIIGRVVRCCVLKDTLSHQWKALVDNIGKGDFSAYIKAEIPADKEFRGVGFEEAPRGMLSHWVVIKGGKIENYQAVVPSTWNSGPRNFNDEPGPYEQALVGTPVADPAKPLEVVRTIHSFDPCMSCAVHVVDTQNGETTQVKVL
>NZ_CP038448.1|WP_017784111.1|3519126_3519378_-|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLSIPSQVVQLHPEDNCVTVDTLGVQRRVSCMLLEEPLQVGDYVLLHIGFVMSKIDEEEAQASLESFRQMVALMPEQDILPC
>NZ_CP038448.1|WP_171269672.1|3519383_3521801_-|carbamoyltransferase-HypF
MTARTPIRSRLRREFHIDGIVQGVGFRPFVYGLALRHGLAGYVLNDANGVTIGAEGSPEQLASFARELRELAPPLSRIDHFSERELPFAHDPDFDGQFHGQFRIKASQQQSAATVAISPDQGMCEACATDVANPADRHHHYPFTNCTHCGPRYTIIRRLPYDRPHTAMAGFAMCPRCAAAYENPLDRRYHAQPVSCPECGPHLSWRNGRGDALAEREDALHTAARALQAGALIAVKGMGGYHLICDARNEQSVARLRTLKRRARKPLAVMMGSLAEAKLHVTGCEAEWKLLASQARPITLLRKRKNDDRLSESRQSAAPLAEGIAPGIPYLGVMLPYTPLHQLLLDACAMPLVATSANGRGSPILIECEAVVRELGGEIDGILDHNRPILHPCDDSLVQWAGGRRQTLRLARGYAPCTPSLKEAVRVPLLAVGAQQKNQLALAFGRQRIYSPYIGDLHSLPMQGHFEQTLATFRDLYDLKPQLLVSDRHPGYLSHQWAKGYCQEQGATHLEVQHHHAHLLGVMAEHNITDPVLGVAFDGTGLGDNGTLWGGELLLADVKGFERVAHLQPFKLVGGEAAIREPVRQLLGLLFESYDLEQIRALDIPLVSKLPIERIRNLHQLWQLGRNTPHTSSIGRLFDAVAALLGVIDTPDYEGEAGLLLEAAALQLPPDEALFPLAFGLSQSAEGLLHIEWAELINTLVSERRKGSSTASLAAGFIRAISNLVLALTERFPGYPVALGGGVFQNRVLMDQLVPALEAAGRQVLTSETLPLNDGGIAAGQLWFAIHHIATHQPVATGCATLSES
>NZ_CP038448.1|WP_025326665.1|3522600_3523200_+|recombination-protein-RecR
MKFSPLLDEMMKALQVLPGVGPKSAQRMAFTLLERERSGGLRLASLLNRALTEIGHCSHCRTFTENDRCEICANPKREENGLLCVVESPADVAAIEQTGQFSGRYFVLMGHLSPLDGIGPEELGLEILERRLKDEHIKELILATNPTIEGDATAWYIADMARAAGVEVSRIAHGVPVGGELELVDGTTLSHSLMGRQRI
>NZ_CP038448.1|WP_171269673.1|3523481_3525395_+|molecular-chaperone-HtpG
MTQSVHAETHGFQTEVKQLLSLMAHSLYSNKEVFLRELISNASDAADKLRFKALSDASLFENDGQLRVRLVVDKENKTLTISDNGIGMTRDQVIEHLGTIAKSGTAEFFKHLSGDQGKDSQLIGQFGVGFYSAFIVADKVTVISRAAGTEPGQGVQWESQGEGSFTVADVTKEGRGTDVILHLRSDEEEFLDDWRLRAVVAKYSDHISVPVEMYKEGTPDREEDGETIVGTPGEWEQVNRATALWTRNPKDIKDEEYQEFYKHVAHDFEDPLLWGHNRVEGAQEYTSLLYIPARAPFDLYNREQKHGLKLYVQRVFIMDDAEQFMPTYLRFVKGVLDSNDLPLNVSREILQDNKVTASLRKACSKRVLTMLNKLAKDDSEKYAKFWSEFGNVLKEGPAEDYANREEIAKLLRFASTAGEGEAQTVSLEDYVGRMKEGQQKIYYITADSYAAAKNSPHLEIFRKKGVEVLLMWERVDEWLMSHLTEFDGKQLVSVTRGELDLGELEDEASKQAQEEAEKANAGLVARVKQSLADAVKEVRVTHRLTDSPSCIVTDDHGMSTQMIKLMRAAGQPVPEQKYILELNPDHALVKKLDTIEDEALFGEWVALLHEQAQLAEQGGLNDPASFVSRINRLLLQA
>NZ_CP038448.1|WP_171269674.1|3525647_3526292_+|adenylate-kinase
MRIVLLGAPGAGKGTQAQFIMEKHGIPQISTGDMLRAAIKAGTELGLKAKAVMDAGQLVSDDIIIGLVKERIAQPDCANGFLLDGFPRTIPQAQAMKDAGVVVDFVLEFDVPDEEIVKRMSGRRVHSGSGRTYHVVFNPPKVEGKDDVTGEDLVIRADDEETTVRKRLDVYHQQTAPLIGFYGKEAETGNTRYVKIDGTQPVDQVSQQLATILG
>NZ_CP038448.1|WP_171269675.1|3526406_3527381_+|ferrochelatase
MTTKTGILLVNLGTPAAPTTAAVKAFLSQFLHDQRVVDLPRYLWCPLLHFIILPTRSPRVAKLYQQVWTEQGSPLMVISLQQRAALEQELKREGVEVPVELAMTYGSPSMEDGWQALKAKGVNRVILLPLYPQYSVSTTASVFDAWAKAMKKERNLPVVRLIRDYHAHPEYIQALAMSVRRHWEQHGQGEHLLMSFHGIPERYENEGDPYGHQCRRTAALLAEALGLAPEQWTASFQSRFGKEEWLKPYTDVTVEGLPTRGVKRLDVICPAFSADCLETLEEIQVQNREIFMDAGGEQFEYIPALNSDQAHIRMMVSLICRELA
>NZ_CP038448.1|WP_171269676.1|3527445_3527838_+|MAPEG-family-protein
MMHITLIYGGLLGLLFLLLSFWVVKRRAQFKVMIGEGEAPEMLSAIRAHGNFAEYVPLTLLLMALCELAGVGALWLHLGGGLLLAGRILHAIGIQIPRAPNKPRLFGTLFFWLSLGLFSVLALVQGLSFG
>NZ_CP038448.1|WP_171269677.1|3528024_3529329_+|inosine/guanosine-kinase
MKFPGQRKSKHYFPVDRRDPLIPQNPLLTELGKAYVVGIDQTLVDIEAHVDEDFLNRYGLSKGHSMLISDDVAERVYEELKANNMVVSEFAGGTIGNTMHNYSVLADSHSILLGVMSQDIRIGSYAYRYLCNTSSRVNLDYLQPVDGPVGRCFTFITEGGERSFGINAGKMDHLDVAHIPEAIIKESSALVITAYLVRGADGTPMKEAAMAAVRYAREAGVPVVLTLGTRFVIDENPQWWRDFISENVTVLAMNEDEAEALTGIKDPLGAADKALDWADMVLCTAGPVGLYMASYTDEDYKRETTHTLLPGVIPEFNMYEFSRPMARDKCRKPARIYSHISPYMGGPEKIKNTNGAGDGALSAVLHDMVANAYHRMNVPNSAKHLSEFLTYSSLAQVCKYANRVSYEVLAQSSPRLSRGLPEKEDSLEEVYWER
>NZ_CP038448.1|WP_171269984.1|3529538_3531119_+|methyl-accepting-chemotaxis-protein
MVLALLGLLLFFCLQIYQQGLMGEKSRQTRAQVETAYSLVAGLEARVRKGELDEASAKAEALALIKGLRYGADDYFWINDSHPTMVMHPMKPELDGKDLSGVEDKQGLRLFVAFADLARAQGAGEVAYYWPKPGVEEPVRKISYIKRFAPWDWIIGTGVYVDDVEAQYQEVLRTLLGVGLVLALLLFAVVGLIVRSIVVPLSQSVSALGNIARGEGDLRFRLPESGRDELSQLSVNFNLFAGQMAQLVGRSQQITAQNREQAHQLAQVVDRTGAIVTGQEQDTLRVASAMEQMTVSSREVGQHAAQAAEAADSALNLAQHGRQVVAQTRETISQLADEMVETVQAVSRLEQETQQIGSVLDVIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLATRTHSSTDEIRQMIQRLQEGAGRVVSSITQLQQLSRSTAERAGDADGAIHAIDGSVHTITAMNSQIATAAAEQSRAAEEINQRLVAITGLAADALAQNRLTEQAASQLALSCDELGALVAQYRT
>NZ_CP038448.1|WP_010674427.1|3531243_3531606_+|DUF2750-domain-containing-protein
MSKLTDNLDANFQLFIEEVRESGQVWGLRYGEDWVVCRSAEFEDADVMPLWSAEGDARLHCVDEWADYEPEVIELEEFLDIWINDLDEDDVLVGPNWNADLEGQELEPIELAKALVELDA

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Crispr_ID: NZ_CP038448_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_8

4308421-4308497

Orphan

Consensus_repeat	Method
AACAAGATCATGCATATGCTCTAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_8

>merge|NZ_CP038448|8|4308421-4308497|CRISPRCasFinder
AACAAGATCATGCATATGCTCTAGCGATGTGACCCCATCGCCAGCATCAATAACAAGATCATGCATATGCGCTAGCG

>NZ_CP038448|8|7|4308421-4308497|CRISPRCasFinder
AACAAGATCATGCATATGCTCTAGCG	ATGTGACCCCATCGCCAGCATCAAT
AACAAGATCATGCATATGCGCTAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_171269468.1\|4303548_4305489_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NZ_CP038448.1\|WP_042650276.1\|4308550_4308982_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|312075
NZ_CP038448.1\|WP_005327814.1\|4296650_4297244_+\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NZ_CP038448.1\|WP_171268913.1\|4314469_4315075_+\|LemA-family-protein	unknown	unknown	gnl\|CDD\|224618
NZ_CP038448.1\|WP_042650271.1\|4299568_4300123_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|368781
NZ_CP038448.1\|WP_042650274.1\|4301832_4303395_-\|AbgT-family-transporter	unknown	unknown	gnl\|CDD\|225525
NZ_CP038448.1\|WP_042650272.1\|4300116_4300881_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_043133480.1\|4298335_4299556_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NZ_CP038448.1\|WP_171268918.1\|4297315_4298242_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP038448.1\|WP_171268912.1\|4315071_4315806_+\|TPM-domain-containing-protein	unknown	unknown	gnl\|CDD\|224429
NZ_CP038448.1\|WP_171268916.1\|4311510_4312410_+\|aldo/keto-reductase-family-oxidoreductase	unknown	unknown	gnl\|CDD\|227322
NZ_CP038448.1\|WP_042650284.1\|4309049_4310066_-\|low-specificity-L-threonine-aldolase	unknown	unknown	gnl\|CDD\|178323
NZ_CP038448.1\|WP_005327789.1\|4306436_4307381_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_CP038448.1\|WP_041206904.1\|4305657_4306359_+\|DUF2982-domain-containing-protein	unknown	unknown	gnl\|CDD\|378593
NZ_CP038448.1\|WP_042649706.1\|4295695_4296388_-\|(d)CMP-kinase	unknown	unknown	gnl\|CDD\|234579
NZ_CP038448.1\|WP_171268914.1\|4313683_4314427_+\|penicillin-insensitive-murein-endopeptidase	unknown	unknown	gnl\|CDD\|236511
NZ_CP038448.1\|WP_042650278.1\|4310932_4311340_-\|transcriptional-regulator	unknown	unknown	unknown
NZ_CP038448.1\|WP_171268917.1\|4310152_4310860_-\|short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|181609
NZ_CP038448.1\|WP_171268915.1\|4312976_4313519_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_081805676.1\|4312486_4312765_-\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240845

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_171269468.1\|4303548_4305489_-\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	2.53303e-106
NZ_CP038448.1\|WP_042650276.1\|4308550_4308982_+\|PAS-domain-containing-protein	gnl\|CDD\|312075	pfam08448, PAS_4, PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.	0.000143922
NZ_CP038448.1\|WP_005327814.1\|4296650_4297244_+\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	2.67815e-136
NZ_CP038448.1\|WP_171268913.1\|4314469_4315075_+\|LemA-family-protein	gnl\|CDD\|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	2.74095e-79
NZ_CP038448.1\|WP_042650271.1\|4299568_4300123_-\|VOC-family-protein	gnl\|CDD\|368781	pfam06185, YecM, YecM protein. This family consists of several bacterial YecM proteins of unknown function.	2.71827e-25
NZ_CP038448.1\|WP_042650274.1\|4301832_4303395_-\|AbgT-family-transporter	gnl\|CDD\|225525	COG2978, AbgT, Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism].	0
NZ_CP038448.1\|WP_043133480.1\|4298335_4299556_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.77809e-59
NZ_CP038448.1\|WP_171268918.1\|4297315_4298242_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.19515e-50
NZ_CP038448.1\|WP_171268912.1\|4315071_4315806_+\|TPM-domain-containing-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.50372e-59
NZ_CP038448.1\|WP_171268916.1\|4311510_4312410_+\|aldo/keto-reductase-family-oxidoreductase	gnl\|CDD\|227322	COG4989, COG4989, Predicted oxidoreductase [General function prediction only].	1.52832e-171
NZ_CP038448.1\|WP_042650284.1\|4309049_4310066_-\|low-specificity-L-threonine-aldolase	gnl\|CDD\|178323	PLN02721, PLN02721, threonine aldolase.	8.72397e-148
NZ_CP038448.1\|WP_005327789.1\|4306436_4307381_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.99133e-44
NZ_CP038448.1\|WP_041206904.1\|4305657_4306359_+\|DUF2982-domain-containing-protein	gnl\|CDD\|378593	pfam11201, DUF2982, Protein of unknown function (DUF2982). This family of proteins with unknown function appears to be restricted to Gammaproteobacteria.	8.53417e-72
NZ_CP038448.1\|WP_042649706.1\|4295695_4296388_-\|(d)CMP-kinase	gnl\|CDD\|234579	PRK00023, cmk, (d)CMP kinase.	1.37022e-130
NZ_CP038448.1\|WP_171268914.1\|4313683_4314427_+\|penicillin-insensitive-murein-endopeptidase	gnl\|CDD\|236511	PRK09429, mepA, penicillin-insensitive murein endopeptidase; Reviewed.	4.26417e-126
NZ_CP038448.1\|WP_171268917.1\|4310152_4310860_-\|short-chain-dehydrogenase	gnl\|CDD\|181609	PRK09009, PRK09009, SDR family oxidoreductase.	5.4263e-31
NZ_CP038448.1\|WP_081805676.1\|4312486_4312765_-\|RNA-binding-protein	gnl\|CDD\|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	2.66511e-36

>NZ_CP038448.1|WP_005327789.1|4306436_4307381_+|LysR-family-transcriptional-regulator
MKYIEEFYLFVKVVQEGGFSHAAAALGMPTGTISRRISQLEEQLGCALLHRSTRKLRLTDEGLRYYERLCTPLAEIEQATGEIQGQETDISGLIRLAAPIALSNTILVDMLADFGLRYPGVQFDISQTNDQAPLCDQDRDLVFFNGELSQTLPNALCLGHIEYGLFASPLYLEKMGIPSHPAQLEEHDLIYCWPHQHWQLSGRDQQTVQIKRTPRLSVNQTQAAVRAARRHLGIVNAPLHYVHPFLQDEQLVAVLPDWQSGKRPFYMLHCQPRFTPLRVKMFADFVEKYSVRYRHHQRDDQFLPAMPLPVASDG
>NZ_CP038448.1|WP_041206904.1|4305657_4306359_+|DUF2982-domain-containing-protein
MKTLHVIPMVRRNGLTLILLGMVITITMIFILFFLREQLLMPVIFLLLAGLMTILVGALKLSEPHFSLSLCQDCLQYHHKYGGWILKWRNIQRIDQPRIHLGWDLVPLPYIGLKIKDYDDFLTLITPRLAVRLLTEQRAVLLQAMSSERPDCLTGGCGAGLLGEGLLEESRFRSSSGQQYEGVIAMLGNRMTRLRDLLGYDLLVPDNSLDRSPVDFVRLLNQYQRESNLIQIN
>NZ_CP038448.1|WP_171269468.1|4303548_4305489_-|EAL-domain-containing-protein
MDVLHTPIWVYDIQRHHIYWANDSALGLWEASSLSELQSRNFSADMAAAIDLLLQRYLGDFQQDRSYNEWWTLSPKGVKKQVYLRLSGIQLAGRQMMMTEAVIDADTLYQESSLATGDTLACLFDNEGCLESGNHHFDMCFGTGISQLTQVFSGCDEAFYTRLSRVGEVVAEGECRTQKGMRWFQYQFRHIQQGARILLTMRDITDRKLEELEHRHLAWHDSLTGLLNRYGLMKSLEAYCGLGGRFALVFMDLDNFKLVNDNYGHKAGDRLLERVAGRLKQICPRDVELARLGGDEFTALVPLNQASERAQEVADLMLSQMSKPLQLSGVPEVTIGGSIGIAIYPDDADDGDNLITRADMAMYQAKQMGRLRWQRFTPSMQQSLHRKLTLKQFLAKAVGRGELSLRYQPQVDVAQGKLIGFEALLRWYNPVLGHVSPAEFIPLAEEMGLIREIGSWVLATALAQMGEWQRQWQVRVPVSVNLSGFQLSASLPGQVAQQLRESNVEAGLLTLELTETVLMLDMKGCIEILDALSEQGIKIAIDDFGTGYSSLAYLNRLPIDTIKLDRSFVVGLNLPVIRATVAMATSLGLGILAEGVEDEHELAALRAQGCHVFQGFLFSTPMTPEEVAAAGFGIRCKLGHYPLIGA
>NZ_CP038448.1|WP_042650274.1|4301832_4303395_-|AbgT-family-transporter
MSQAAVNERPASPNGWLNRFLNGVEKAGNKLPDPAMLFLYALLIVWVGSWIGSQFSFDLVNPRTGEAVVVNNLLTGAGLAEFLASMVTTFTGFAPLGIVLVAMLGVGVAEQSGFINTGLKKLLKVTPARFLTPMLILVAIVSHTAADAGYVLVIPIGGIIFHAAGRHPLAGIAAAFAGVSGGFAANFLPSGGDALLQGFTQSAAQLLDPDYMVNTLCNIIFTGASSLLIICVGWFVTEKIVEPRLKQVPLNEDLESADEMGRYSAQESRAFNWAGFAMLAAVVLLGLALSPDDSPMRAPDGSLTTFAAPVMKSIVPLIFLLFILPGIVYGFVAGSFKSGKDVIDAMSATMNKMGSYMVMAFFCALFIKAFGDSNLGTLLALSGAEVLHALALPGEVTIVGMILLTASVNLVVGSASAKWALISPILVPMLMAVGISPELTQAAYRVGDSASNIITPLMVFFPLVVVYCQQYVKSTGIGTLVSMMLPYSLAFLVSWTCFLLLYWALGFPLGLQAPYVYPAP
>NZ_CP038448.1|WP_042650272.1|4300116_4300881_-|hypothetical-protein
MILTLILLSIGALLFLVIAYNVVQQYKQKAEADKRQAIARHKAVADETEEVLLNVNLVPFSKNMVLLLQHRILDAYRAIVQVMPNPQVKQRIIDVQTQIKNVQENYSSQDEGHFKTPESDRQAIQMLQLAKKMRAVLRVEHNKGKIDPQGFAQEDRRLELMQLKINIANLIKRAMDAQIQGQYGTCRQLYTKGLGALANVSDKDPYLLAREEDMRQGMRQLEEHLQQHSEKELQNIKDKEADELDVLFQPKKKW
>NZ_CP038448.1|WP_042650271.1|4299568_4300123_-|VOC-family-protein
MVIMSHPLDTTLGPMAPFVCQLLTEMHALMGECEAPQVDHLCYRAATLPEYLALKETLARHGVLLVEGMIGGRPIATYRLHQPVCWQQITVPCIELAAPKAGRAHQAGLEHIELVVPSLPALVAAHPGLAFKTANMGDGRNPDVGLMLPSGQIKFHLRPLSEVIDEELHTGAVVPVPADYYDGL
>NZ_CP038448.1|WP_043133480.1|4298335_4299556_+|MFS-transporter
MIEVGSREWIRATLALSLGSFLVFLNLYQTHPLLPLLAEVFSVSSLSAGWTLAGCTAGLAGSLLICARMADRFGRRRIMLWTLTCAILLSLCIPWVTRFDLLVCLRVLQGALLAGLPATAIAYMGEEFSKRALLSAVGVYIAANSLGGIAGRVVGGLLAGWFGDWQHTFLGIGFISLALLPLVIWLLPAQTRFVAVEAAPGQLRRAIQSHLGNPLLLGAYLIGGLNFMVFLNQYSYLTFLLAKAPFSLPTQWLGMLFLTYLTGTLASSLSGRCAHRFGAQRLLLAGIALMALGSLALLQGTLAAIIGGLLISSFGFFLAHACASAWVGQHVEHNRALASSLYLVGYYLGASLGGLYLHPFWERGGLWGLVLGIELVLCVTAALSLWLGHLKGRTAPPLSCHASSRQ
>NZ_CP038448.1|WP_171268918.1|4297315_4298242_-|LysR-family-transcriptional-regulator
MDLKQLGYLLAVRDAGSFTKAAQGLHVAQPAVSMAIAKLEQQLDLRLFDRQDRSVRLTPEGEVLCRHAERLLLQMHQAQAEMAELKGLERGEVRIGIPYMMGSYYFPPILMAFKHRYPGLKIRVEEAGTRELLSRMVDGSLDLAILITSDLPPALEGAQLLREEMLMVVGEEHPLRGASAVSLPQFFNQELAMFRRGFYHREHMEALAQGLGIEPNIGFESNLIPLLKAVVRQGFAVTTFLRMALEEETTLSGIPFAPPIFLDLCVAWRRGDPLSMANRALRDFLLAQAKPEPTPDGALRDNNLRDNR
>NZ_CP038448.1|WP_005327814.1|4296650_4297244_+|GTP-cyclohydrolase-II
MSSITLVAKSKLPTPWGIFTLVGFQETGTGKDHAALVMGDIADGEPVLGRIHSECLTGDALFSLRCDCGFQLQAAMEKIAKAGRGVLLYVRQEGRGIGLLNKIRAYHLQDQGADTVEANVALGFAADMRDYTICADMLKALEVKSLRLMTNNPRKLKAMESFGIPVAERVPLQEGRNPHNEFYLSTKANKLDHLFKK
>NZ_CP038448.1|WP_042649706.1|4295695_4296388_-|(d)CMP-kinase
MPQMAPVMTIDGPSGAGKGTLCQLLAEKLGWHLLDSGAIYRVLALAALHHDVELDAEAALVPLAANLDVQFQVDGGQVKVVLEGEDVSRTIRSQEVSDAASKVAVFPRVREALLRRQRAFRQLPGLIADGRDMGTVVFPEAEVKIFLDASAEERAQRRYKQLQDKGFDVNFERLLTEIRERDDRDRNRAVAPLKPAEDALVVDSTSMTIDDVLATVLAYAEQQLGDVSTS
>NZ_CP038448.1|WP_042650276.1|4308550_4308982_+|PAS-domain-containing-protein
MEIREFHWLMNIVQNLDVGLVVLDKGYRVQVWNGFMESHSGRLAGEVRDQVLFDLFPDVDRAWLERKANMVFKLNNRAFSTWEQRPYLLRFSNYRPITGSAPHMYQNLTLVPLADFGGEVTHLAIMIYDATDEAMLITGQRQG
>NZ_CP038448.1|WP_042650284.1|4309049_4310066_-|low-specificity-L-threonine-aldolase
MRYIDLRSDTVTQPTEAMRQSMLHAEVGDDVYGEDPSINALEHKGAELLGKEAALFVPSGTMSNLLAMMSHCQRGEGAVLGSASHIYRYEAQGSAVLGSVALQSVPMQADGTLALKDVRAAIAPDDAHFVQTRLVCLENTHNGKVLPLPYLREMRDFVDEHGLLLHLDGARLFNAVVASGEPVAAIAAPFDSISVCLSKGLGAPVGSLLVGSHGFIARARRLRKMLGGGMRQAGILAQAALFALDQHVTRLADDHRRARRLAEGLASLPGVALNMEEVQTNMVFLRLTQGDPATLLGFMKERGILFSGYGELRLVTHLQITDDDIDEVIDAFTEFLNG
>NZ_CP038448.1|WP_171268917.1|4310152_4310860_-|short-chain-dehydrogenase
MSYLILGSGGLGGALAHELASRGEEWLLAGRQLPKGLDPACYFPLQEVDPLSFDALFTLYDTATLPNVVINTIGLLHDLSHMPERRVEEVTPQWLGESLQANAWPHLALGASLSRLMTFESRLWLCTLSDLAGSLKEAHREPARRYSYRMSKAALNMGSRILAAEWAERFPGAGVITVHPGLMDTPMQQPFRQEIDPALLQDPALVAPQLLDLLASLNQAHSGRFVDLRGQPLPW
>NZ_CP038448.1|WP_042650278.1|4310932_4311340_-|transcriptional-regulator
MEGFAARLQSLIGEGSVSAFARKVGLSEALIRKYLKGAEPGLGKANQIAMGANCSLEWLATGCGYLYRQAEVVDRDALAAAGALVQETLLGQPMPDEEQLVTLLAYYQFLRSHKQADGFLDLARAREFGRHLAEA
>NZ_CP038448.1|WP_171268916.1|4311510_4312410_+|aldo/keto-reductase-family-oxidoreductase
MPVSRLALHHQGPTFSRLIMGYWRLMEWQLSPATLLDLMKYHLDLGVTTIDHADIYGGYQCEEAFGRALRLEPSLRSRMEIVSKCGIALTAKPEHALNHYNTSKGHIVASAEASLQKLGTDHLDLLLIHRPDPLMNADEVAEAFISLEQAGKIKHAGVSNFTPHQFALLQSRLPFPLVTNQLEISPLHQEGTLDGALDQCQQLGIKPMAWSCLGGGRLFNDPAYAPLRAELELIRQELGTQTIEQVVYAWVMMLPSQPLPLIGSGKRERIAAAVAAESIVLSRQQWFRIRKAALGYDVP
>NZ_CP038448.1|WP_081805676.1|4312486_4312765_-|RNA-binding-protein
MKIYVGNLSYRMTADELTNVFSQFGQVDKVDIIIDRDTGQSKGFGFIEMPVNGDAEKAIAELHGTEIGGRTITVNQAKPKTDAPRGRPQRHR
>NZ_CP038448.1|WP_171268915.1|4312976_4313519_-|hypothetical-protein
MRVSELALQGGVNWLMPPARRFYGVMICLLLASLGTVVAALLLGYPEMGLLPWVGLVFGGIVLVMMVLPRNWQRWRLAELAWDDHHLYLLNGGEDRALALPKAALVGIERDRKVGHDGQWLDFSLDLGLDEETLADAAGLLGLTREGTHEVAPGVYRFGFKRAWHSRRALNKLLAALQPA
>NZ_CP038448.1|WP_171268914.1|4313683_4314427_+|penicillin-insensitive-murein-endopeptidase
MFATALLLTTSALYAEAIGGYAAGCLKNAVALPLTGPGYQVIRSKRLRYYGHPDLIHYLQGLANQTRLAGMPDLYIADLAMARGGPFTSGHRSHQTGLDADIWFRMADRPISQWEQDAPKEWALIDEPSYRMLPGRFGPQQLNLLRLAANKPEVARIFVNPVIKAEVCKRAADEPWVAKLRPWVGHFSHFHVRLRCPANNPDCQPQAPIPPGNGCDAELASWLKDKPQLPKVSMSYRAPALPKRCEG
>NZ_CP038448.1|WP_171268913.1|4314469_4315075_+|LemA-family-protein
MENNKMAISLRHRATQCLLTFTLLLGLTGCGMNNIPTLDEQVKASWGQVENQYQRRTDLIPNLVATVKGYASHEQETLKAVTDARARVGSLQVSDPAQLKAFEAAQDQLSSALSRLMVVVERYPDLKADQQFLTLQAQLEGTENRISVARRDYIEAVRQFNTEIRTFPGVIWSKLLYSDLEAKPTFSAKPGADEAPKVSFQ
>NZ_CP038448.1|WP_171268912.1|4315071_4315806_+|TPM-domain-containing-protein
MTMMLRALLPLLLLWTTTLQAAPAFPPLSGRVVDEAALMSRKQAHQLTQQLAAFEKRSGIQLVVVSIDSLDGETIEEYGYQLGRHWGIGQKGKNNGVLLLIAQDERKVRIEVGYGLEGALPDAIAANIIQTRILPAFKRGDMVAGVVAGSQGIMQALAGEYQPVDNASKEEKQGGPWLFILVVIVMIVLHNLRGGGGGGGRGRRNAAYLVGGFGAGRTGGGFGGGGCFSGGGGSFGGGGASGGW

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Crispr_ID: NZ_CP038448_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038448_9

4610952-4611075

TypeV

Consensus_repeat	Method
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038448_9

>merge|NZ_CP038448|9|4610952-4611075|CRISPRCasFinder
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCATCGCCTGGCCATCTCCCTCACCCTCCCTCAAAGGGAAATGACGGATGATTGCCCTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT

>NZ_CP038448|9|8|4610952-4611075|CRISPRCasFinder
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT	CGCCTGGCCATCTCCCTCACCCTCCCTCAAAGGGAAATGACGGATGATTGCC
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038448.1\|WP_042649658.1\|4614537_4616043_+\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP038448.1\|WP_005331987.1\|4607801_4608002_-\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_CP038448.1\|WP_119196702.1\|4624519_4625797_-\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341169
NZ_CP038448.1\|WP_042648288.1\|4606200_4606845_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NZ_CP038448.1\|WP_005331986.1\|4607055_4607805_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_CP038448.1\|WP_042649656.1\|4618679_4619717_-\|porin	unknown	unknown	gnl\|CDD\|225744
NZ_CP038448.1\|WP_042649660.1\|4613404_4613923_+\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP038448.1\|WP_005331989.1\|4608152_4609148_-\|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl\|CDD\|234808
NZ_CP038448.1\|WP_025201450.1\|4600539_4600842_-\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NZ_CP038448.1\|WP_119196703.1\|4621261_4624519_-\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP038448.1\|WP_005331991.1\|4609147_4610917_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	unknown	unknown	gnl\|CDD\|183016
NZ_CP038448.1\|WP_021139619.1\|4601338_4602544_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP038448.1\|WP_005329100.1\|4616199_4617390_-\|aspartate/tyrosine/aromatic-aminotransferase	unknown	unknown	gnl\|CDD\|181731
NZ_CP038448.1\|WP_034523852.1\|4600834_4601191_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_042648289.1\|4604234_4606088_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP038448.1\|WP_042649661.1\|4611120_4613376_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|236924
NZ_CP038448.1\|WP_042649657.1\|4617535_4618477_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038448.1\|WP_042648290.1\|4603386_4603941_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|182763
NZ_CP038448.1\|WP_042649659.1\|4613916_4614411_+\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP038448.1\|WP_119196704.1\|4619988_4621257_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574

Protein	Function_ID	Function_description	E-value
NZ_CP038448.1\|WP_042649658.1\|4614537_4616043_+\|DUF853-family-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP038448.1\|WP_005331987.1\|4607801_4608002_-\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	2.27803e-17
NZ_CP038448.1\|WP_042648288.1\|4606200_4606845_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	2.53899e-164
NZ_CP038448.1\|WP_005331986.1\|4607055_4607805_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	2.55943e-155
NZ_CP038448.1\|WP_042649656.1\|4618679_4619717_-\|porin	gnl\|CDD\|225744	COG3203, OmpC, Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane].	9.29491e-41
NZ_CP038448.1\|WP_042649660.1\|4613404_4613923_+\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	8.76488e-47
NZ_CP038448.1\|WP_005331989.1\|4608152_4609148_-\|tetraacyldisaccharide-4'-kinase	gnl\|CDD\|234808	PRK00652, lpxK, tetraacyldisaccharide 4'-kinase; Reviewed.	2.0377e-167
NZ_CP038448.1\|WP_025201450.1\|4600539_4600842_-\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	1.90862e-10
NZ_CP038448.1\|WP_119196703.1\|4621261_4624519_-\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	3.00969e-78
NZ_CP038448.1\|WP_005331991.1\|4609147_4610917_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	gnl\|CDD\|183016	PRK11176, PRK11176, lipid A ABC transporter ATP-binding protein/permease MsbA.	0
NZ_CP038448.1\|WP_021139619.1\|4601338_4602544_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.42025e-34
NZ_CP038448.1\|WP_005329100.1\|4616199_4617390_-\|aspartate/tyrosine/aromatic-aminotransferase	gnl\|CDD\|181731	PRK09257, PRK09257, aromatic amino acid transaminase.	0
NZ_CP038448.1\|WP_042648289.1\|4604234_4606088_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP038448.1\|WP_042649661.1\|4611120_4613376_-\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|236924	PRK11539, PRK11539, ComEC family competence protein; Provisional.	3.38185e-113
NZ_CP038448.1\|WP_119196704.1\|4619988_4621257_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.38697e-70
NZ_CP038448.1\|WP_042648290.1\|4603386_4603941_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	8.94173e-84
NZ_CP038448.1\|WP_042649659.1\|4613916_4614411_+\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	8.75081e-28
NZ_CP038448.1\|WP_119196702.1\|4624519_4625797_-\|restriction-endonuclease-subunit-S	gnl\|CDD\|341169	cd17280, RMtype1_S_MspEN3ORF6650P_TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Marinobacter species EN3 S subunit (S.MspEN3ORF6650P) TRD1-CR1, Methanothermobacter marburgensis str. Marburg S subunit (S.Mma2133ORF14720P) TRD2-CR2 and Nostoc species NIES-3756 S subunit (S.Nsp3756ORF27100P) TRD1-CR1. The recognition sequences of Marinobacter species EN3 S subunit (S.MspEN3ORF6650P), Methanothermobacter marburgensis str. Marburg S subunit (S.Mma2133ORF14720P), and Nostoc species NIES-3756 S subunit (S.Nsp3756ORF27100P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	4.72969e-17

>NZ_CP038448.1|WP_005331991.1|4609147_4610917_-|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA
MQQETSQESWPVFKRLLGYVRDRKLGLVGGIIGMLGYAAVDTTFVYSIKPLIDQGLNGNDSSVLKWMPFFVLGIVALRGCAAFLSNYCMAWVGNHVVMRLQQQVFSHLMAMPMSFFDRQNTGNLLSKVTYDAGQVSSAASSTLVSLVREGATVIGLLGLMFWHSWQLSVIFLVVGPVVGVLIGLISRRFRKISRHIQQAVGDITTSTEQMLKGHKEVLMFGGQQVEDKRFYQVSNRMRQQTMKMVAADAIGSPIVQMVASVALAVFLYVATIDSVKATLTAGTFTVMVTSMMMLLKPLKSLTDVNNQFQRGITACQSLFGLLDSTPEQDTGTRTLERARGEIEFRNVTFTYPTKDTPALHNISFKVEAGKSVALVGRSGSGKSTIASLLTRFYDIEQGEILLDGVNIREYKLSELRKQYALVSQHVHLFNDSVANNIAYAAEEKYSREEIQHAARIAHADEFVRKMPEGYDTVIGENGASLSGGQRQRIAIARALLRDSPVLLLDEATSALDTESERHIQAAIDELCKARTSLVIAHRLSTIEKADEILVIDEGHIVERGNHDALMAQQGTYAQLRAIQFGNVAVSNKG
>NZ_CP038448.1|WP_005331989.1|4608152_4609148_-|tetraacyldisaccharide-4'-kinase
MLERLWYGKSGWRWALAPLALLFALVSGGRRFAYWRGWFSTYRASLPVIVVGNISVGGNGKTPVVVWLVEQLQARGWRPGVVSRGYGGKAPHYPYRLDATSTTAQAGDEPVLIARRCGCPVVVAPRRADAVRLLEQSGEVDIVITDDGLQHYALARDIELVVVDGARRFGNGCLLPMGPLREPMTRLKRVDAIICNGGTPAQGEYPMALVAAAPRRVCDDAPLEAPLTGPVDALAGIGHPPRFFATLTGLGYELAERVGYADHQAFDRDELLARFGQRPLLMTEKDAVKCRAFAPPHWWYLPVSAELPAALLDTLLQRLTPLQAPGPDHAH
>NZ_CP038448.1|WP_005331987.1|4607801_4608002_-|Trm112-family-protein
MALDIKLLDIIACPVCKGKLHYQPQSDKAAHELICRFDRLAYPLEEGIPVLLENRARHLPLEELKP
>NZ_CP038448.1|WP_005331986.1|4607055_4607805_-|3-deoxy-manno-octulosonate-cytidylyltransferase
MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDELVRQALRATGVEVCMTSPDHQSGTERLAEVCRHYGFAADTIIVNVQGDEPLIPPVIIRQVADNLAAATAPMATLSVPIKDAEEAFNPNAVKVVTDKDGYALYFSRASIPWDRDRFAKSHEQIGNHYQRHIGIYAYRAGFIQRYVDWAPSALEQVEALEQLRVLWYGEKIHVAQALEAPPVGVDTQTDLDKVRALLAN
>NZ_CP038448.1|WP_042648288.1|4606200_4606845_-|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MINVFLVDDHELVRTGIRRILEDVRGIKVVGEAQSGETAVAFCRQHHPDVILMDMNMPGIGGLEATRKILRIRPDVRIIVLTIHSENPFPTKVMQAGAAGYLTKGAAPDEMIHAIRLVHSGQRYISPEIAQQMALSQFASADENPFKPLSERELQIMMMITKGQKVTDISEQLNLSPKTVNSYRYRLFSKLNINGDVELTHLAIRYGMLDADTL
>NZ_CP038448.1|WP_042648289.1|4604234_4606088_-|excinuclease-ABC-subunit-UvrC
MTLSPEPLFDSKAFLSAVTHQSGVYRMYDGGGTVIYVGKAKDLKKRLASYFRTNVDSIKTRTLVRQIADIQVTVTHTETEALILEHNLIKQYQPRYNVLLRDDKSYPWIIITAHQHPRIGVHRGVRKVKGEYFGPYPSSGAVRESLHLMQKIFQVRQCEDAVYANRSRPCLLYQLKRCAGPCVAGLVSEAEYAQQVELAKLFLAGKNQQVIGELVGKMESASGDLRFEEAARYRDQIQALRRVTEQQSVSGNVLDELDVVGVAFEQGTACIHVLFIRQGKVLGSRSYFPKVPADTPLDEVVQSFLLQFYLSGQGGRQIPSEVLLDVALEDENVIAETLSQTAGYKVRVQSRTRAERARFIKLASINAQTALRSRLAHKSTITARYDQLEELLELERPIARMECFDISHTMGERTVASCVVFNREGPLSSEYRRFNIDGITGGDDYAAMEQALERRFGKQQEPDKVPDVLFIDGGLGQLRRAEEILARQLEFLGGKYPLLVGIAKGVTRKAGLETLILGESHEELHLPADMPALHLIQHIRDESHRFAITGHRARRAKARTTSTLEDIPGVGPKRRQALLKYLGGLQEVKKAGVDELAKVPGISQELAQSIHDALHSL
>NZ_CP038448.1|WP_042648290.1|4603386_4603941_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MTNIPNLLTFFRILLIPVFVILFYLPYQWSYLAAALVFILAAATDWFDGYLARKLNQSTAFGAFLDPVADKIMVAAALVVIVEHYNTIWVTIPAMTMIGREIIISALREWMAELGKRSSVAVSWIGKWKTMIQMVSLTGLIWQYDIWLVWLSYVLLYVATVLTFWSMFQYMKAAWGDLTYHSRF
>NZ_CP038448.1|WP_021139619.1|4601338_4602544_-|site-specific-integrase
MQTKFRFTNAAIKALPAQQRDAGATELEFSDTEVIGLKLLSGKSQGSKRFLLRYTLQGKKRSIALGRFGDIDVSQARTIARKYKAMLAEGIDPVAERDSYKTEPTLSEFFWQTFLPHLKTIGKRSINSDIQRFKHNIEPRFGAMRYRQLKAMDVLQLQSEMVHPNNPQQTAYAPSTANRVLAQLKTMGSYAVRWGILDTNEAAKIKLLKEDNARTRFLSIEEMKRVIEVALQDRNQAAGSFIAMLYLTGARKSEVLLAKWEHVNWEDKTLFVPLTKNGKSRIIYLSALAIDILEKLPRIAGNPYVFASQHIRCQGKPIGEPRCAYERVLQKAGIEDRDEVCFHTARHSVASALVSSGQYSLYDVKAQLAHASIQSSQRYAKLTSERSRNISEGLSSMIQAE
>NZ_CP038448.1|WP_034523852.1|4600834_4601191_-|hypothetical-protein
MEWPEESLLAAYPALHASVMEQIIEPFSSVEEARAFWDATGCSLVIIEMTDSMSEFQAMPQHTQNQVMFGLRYPEQEFAISEDWRLLLAILNDEGAGIYLLIHSDAPLLPTLEAMHHE
>NZ_CP038448.1|WP_025201450.1|4600539_4600842_-|DUF1232-domain-containing-protein
MSNPSHSDIMRKLKEIKGIKELLEKAVLLYVLLTDGDLPVWCYALIIGALAYLVNPFDVVPDPIPFAGYLDDLSVITSALAALPVKSHHRQSAKDRMRSL
>NZ_CP038448.1|WP_042649661.1|4611120_4613376_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MDLRLLSFALGASSSLLWPWLPSTAWGGALLALAILLAHGRHWRLMFLVLGVLWMQLNLQYRLAWLDKLETQTSHIITARVQSTESSGDKPRDKFARLLLRVETLDEQPLGVATLVRINAYQALSPLPAGSRITLVSSLKPAHGLANEAGMDGRRLLLGKGITATGNLRRLIEVQGAAPGMRERWLAAASTAWQGLEQAPLLAALSFGEQGGITDAQWDLFRGSGLTHIIAISGQHIALVAVLGWWLGRLLGLRGAILVSLLFAAVYSWLAGFAVATERALIMVLVWSLLRWLKRDWPSHRIWLWAFVVLVLWDPFALYSAGFWLSFMAVALLLLASLLHARPGLVRLQCLLLLGLLPLQLLLFEGVAPLALLLNLLALPLFCLGIIPLSLIGVLLAPISTALAHGLFWLSDLGLTWVLWGLGLLADHLQLWWSVPGWLMPVSTLLVLLWGAWHLPGGRGLLLPVGAALLLGAWPAPTPWQVRVLDVGQGLSVLVTRGERGILYDTGDRYPGGYNMAEAAILPVLNRLDVRVLDALIISHKDRDHAGNRQTMLQAMPVRRELSSFGFARSTTLCRRGQRWHWQGLDFRVLWPERPGAGRNNDSCVVQISDGRHRLLLSGDIEQEAERRLLALESKGEGGVFASTSASTRFSTLASAVLVSPHHGSRTSSIPGFVAAVNPDVVIHSAGDRNQWQFPRPEVVARYQGARQWVTGQDGAILIEAGEAGLEIRPDREQGPWYRRNGHWWRPRLWH
>NZ_CP038448.1|WP_042649660.1|4613404_4613923_+|DUF2062-domain-containing-protein
MPKRLIKRWLPDQDKLKEHKHLRLFGKLLLDASLWHLNRRSAAGAFAVGLFMAWIPLPCQMLLAAGGAILFRVNLPLSVALVWLSNPVTMPPLFYGAYLVGCQLLGHPAQHIDIQFTWAWLVSVFETLAPPLLLGSLVLALLSSLLGYTLIRTFWRINTVRQWQKRKEARAC
>NZ_CP038448.1|WP_042649659.1|4613916_4614411_+|DUF2062-domain-containing-protein
MLSRWLVRIKINPDTLRQQKWFALFGERLLTPALWQGGTRALSGAVAAGLFASWIPVPMHSLVAVGLALAFSLNLPLALLAVWFNNPLTLPFMYLYAYRTGCLVLHQTPEPFHLTWSLHWLEHEAATLAPPFLLGSLLLAVLTATTGALLTLLMLQLGRLSHSR
>NZ_CP038448.1|WP_042649658.1|4614537_4616043_+|DUF853-family-protein
MAQPLTLAYANGQPIALLPAMANRHGLITGATGTGKTVTLQVLAEGFSRLGVPVFLADVKGDLSGLGAAGTPSTKLDARLAQLGIPTPAFAASPTLFWDLFAEQGHPVRATISDMGPLLLARLLGLNDTQSGVLELVFKVADDEGLLLLDLKDLRAMVQFAGDNAKSLTTRYGNVSTASIGAILRNLLTLESAGGDHFFGEPMLDIQDLLQTDGAGHGHINVLAAGKLTQSSRLYACFLLWLLSELFEQLPEVGDPDKPVLVFFFDEAHLLFNDAPKALLEKIELVVRLIHSKGVGVYFVTQSPADIPDSVLGQLGNRVQHALRAFTPSDQKAVRIAANTLRANPAFDAAGVITELGVGEALVSLLDEKGRPCVVERAFIAPPASRIGPLNDAERQVLIQGSVLHGRYETREDRESAFERLNGGAPTAADDAPQTPSEQGGGLLDALNGILFGRTGPRGGQHDGVVQTAAKSVARTLGNEVGRQLVRGVLGSLLGGSKRRR
>NZ_CP038448.1|WP_005329100.1|4616199_4617390_-|aspartate/tyrosine/aromatic-aminotransferase
MFEKVVAAPADPILGLTEAFRADSRSHKINLGVGIYKDETGATPILHCVKKAEQKLLTDEKTKNYLGIEGNIEYGRIVQQLLFGQDSALVASGRAKTAQAPGGTGALRIAAEFVVRNGLAKTIWISDPTWANHVSVFQAAGLTVKWYKYYDAATKGLDFAAMQASLAEAQAGDLVLLHGCCHNPTGIDPTSDQWRALAKQSAAAGWLPLFDFAYQGFARGIEEDAEGLRIFAECHDELLVASSFSKNFGLYNERVGAFTLVSATKAIADVAFTQVKTVIRANYSNPPSHGAAVVTTIVSDPALYAEWVEEVAAMRVRIREMRELLVEKLSALGVSQDFSFIREQNGMFSFSGLSKDQVERLKSEFAIYIVGSGRISVAGITRANIDPLCDAIAKVL
>NZ_CP038448.1|WP_042649657.1|4617535_4618477_-|hypothetical-protein
MIDFSHPEWRALAQQLLGHSPVVIRGRQWQPLVGLLKDNQLLLAHGSNSYELTPAGRRYLTRELMLAEIATAPPEPEEWLHAQGWQLGEQVNERVLAALYRKSDVNFTPNEQIDFEDKGIRLCADQLLRLRSAQPFSLFFSSGTLIDAAPWLQALGEVSLPERTRADLGKILWGEGNIERVITTDSVGAFAELLLESGSLLVWAPPSASLALQQVVAALPPNVLWSHLTALDPAGVDRVQALAQRLGRPASWWLPRDLAPIKEAYAAPLQDARPWEPSRIPRPLRAWCSDLVESNRGLSAEVCALASGWHAIG
>NZ_CP038448.1|WP_042649656.1|4618679_4619717_-|porin
MKKTILAIAIPALFASAANAAVVYDKDGTSFDIYGRVQANYYGEHDDTDAELVGSSRLGWSGKVALNNTWSGIAKTEWQVSAENSANKFDSRHIYVGFDGTQYGKIIFGQTDTAFYDVLEPTDIFNEWGDVGNFYDGRQEGQIIYSNTFGGFKGKLSYQTNDDKAVKVTDIGQGIKEDAIYGPKAKRNYGYAAAAGYDFDFGLGLNAGYAYSDLESTASSASGDKKEWALGAHYAINGFYFAGMYTQGDLSYDNTTQGSNKDKGRGYELAASYNVDAWTFLAGYNFAEGKVLSNSSGSSYEDIVDETLLGVQYNFTSKLKAYTEYKIQGIDDLDDEFTVALQYNF
>NZ_CP038448.1|WP_119196704.1|4619988_4621257_-|ISL3-family-transposase
MLDLLNLPGIKPVDMRHEGKCLVIVAEPVTVDVPLCGDCNTPMHRHGTRKNKFMDTPLYMEPVRLEVQRPRFRCESCGKMSMPELSFLDDKRRATKRLVDVIRQQCLGTTFHALAEQTGVAVNTVKNIAHDLIEELSQTVRYETPVIMGIDEVNLAGGYRCVITNLATNNVFDMLEHRTQEHLKPFFKDLPDADKVEWVCTDMWRPFKRSFAQHLPNAKLVIDKFHVVKMASEALEAERKNYQAQLSKEDRIYVKKSIRWLTLKRPGNLTPAEQKALEVVKQAIPELAVAYDFKEAFFCIYDEPDKQSAQNAFEAWENSLPPYGMEPFKKLVKTVHNHYDDIFAYWDAPFSITNGYTEGLNGLIKMSNRLGRGYSYPIIRAKTLYSKEARKVGSGIRAGHGKVEYGPHIPTLLKQAESGELD
>NZ_CP038448.1|WP_119196703.1|4621261_4624519_-|type-I-restriction-endonuclease-subunit-R
MQSAAHQEKHFQQYIIDRLVEQGWKLGDSKFYDTERAVYPEDLESWIKSSGQQGKWEKLERLNGTKTLEVLMDRLDKALEKQGTMQVLRQGFSIAGCGLIEMTEAAPEDRRNEAVIKRYQANILRVVPELKYHPAREFAIDLVLFINGLPVATVELKTDFTQSAEAAMDQYRNDRLPYDPKTKRREPLLTFKRGAVVHFAMSDSEIMMATKLDGENTFFLPFNKGRKDESGAVHAGNPPGEIKADGTQEYPVAYFWEAVCQPDSWLRIFHSFVYVEKKDVVDIQGNWSKKETLIFPRFHQWTAVNQMLTDARENGAGMTYLCDHSAGSGKTSTISWTAHDLVKLREDNGDSVFNSVIIVTDRNVLDGQLQDAVKQIDHQFGVIAAIDRQKSSKSKSKQLSEALLSGTPIVVVTIQTFPYAMEAIITDKALKGKNFAVIIDEAHNSQTGSTAAKLQAALGMSGQGKMSTMTVDELLEQLQKSRARPDNISYFAFTGTPKHSTLMLFGRPTDPSQPASNDNPPQAFHLYTMRQAIEEKFILDVLKGYVPYKTAFNLSKQLEDSKRVSGKAAKRALAQWMSLHPTNVTQKVQFIVEHFTKNVAHRLDGKAKAMVVTSSRAAAIRYKKAFDRYIEQHSEYGFIHSLVAFSGKMTGKQVMHQDDSEFKDDVFIVDENEEFTEQSMNPDVQGQDLRFAFDRPEYRVMLVADKFQTGFDQPKLVAMYVDKKIANHVEIVQTFSRLNRTAPGKDEVFIIDFVNDPENVRQAFTTYNKGAHIDEVQDLNVVYEIKERLDEHGLYDDKDLAAFKEARFKTIRDITHTKSPQHKALYAATAGATALYNDKMKMLRDGMATWEAAFEKARAKGDEAGMKSADHHQDEYAEQIKALIGFKSDLGRFCRTYSYIAQLIDFGDPELENFAAFAKLLQKRLLHEAPETVDLTGLVLTGFDINARSDNAEDEGETPVLQPIGAGGGGVAGDKPKFVKEIIERLNSLFGEATPIQDQVAFVNQISAITGESDVVMAQVESNTREQAMKGNLPGAVQQAVVRALSSHQKLATQVLKSDRQGMTALVDMVYDLLREGKDIDLDMD
>NZ_CP038448.1|WP_119196702.1|4624519_4625797_-|restriction-endonuclease-subunit-S
MSQYRAYPAYKDSGIEWIGQVPEHWKVARVKRLASLRNERRNDVSTDTIYIGLEDVEAGSGQYKPTNGSSRQSEDSTVGIFYEGDVLYGKLRPYLRKAIISEMAGCCSTEFLVLRAEKTEPRWLQEWLLTPDVTHQIESGCEGAKMPRADWGHIGSIEVVYPDQPEQAKILTTLDRETARIDALVEKKNRFIELLKEKRQALITHAVTKGLDPNVKMKDSGVEWIGLVPEHWDVKPFFALVTELNRKNVGLVETNILSLSYGNIIQKPETRNMGLTPESYETYQIVESGETVFRFTDLQNDKHSLRSALVTQRGIITSAYMAVKPHSIDSTYFAWLMRSYDLCKVFYAMGGGLRQSLKFEDVRRLPVLIPPVDEQSAITNTINAGTARIDALVEKTEQSITLLKERRAAFITAAVTGQIDLRGKQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

38 : 62990

Escherichia_phage(23.81%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012564931.1\|38_986_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_171269884.1\|1195_2242_-	EpsG family protein	NA	NA	NA	NA
WP_171269997.1\|2252_3308_-	glycosyltransferase	NA	NA	NA	NA
WP_171269885.1\|3345_4440_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_171269998.1\|4436_5393_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_171269886.1\|5974_7225_-	O-antigen translocase	NA	NA	NA	NA
WP_171269887.1\|7221_8325_-	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	4.1e-45	32.8
WP_171269888.1\|8321_9239_-	WxcM-like domain-containing protein	NA	NA	NA	NA
WP_171269889.1\|9317_10178_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	8.5e-107	64.9
WP_171269890.1\|10174_11263_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.2e-97	51.2
WP_171269891.1\|11314_12394_-	UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase	NA	NA	NA	NA
WP_171269892.1\|12863_14849_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	5.3e-19	26.5
WP_171269999.1\|14845_15874_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_171269893.1\|15880_16831_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_171269894.1\|16830_17643_-	glycosyltransferase	NA	NA	NA	NA
WP_052815422.1\|17651_18371_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-09	24.6
WP_171269895.1\|18374_19118_-	ABC transporter permease	NA	NA	NA	NA
WP_171269896.1\|19121_20045_-	glycosyltransferase	NA	NA	NA	NA
WP_080989948.1\|20064_21105_-	acyltransferase	NA	NA	NA	NA
WP_080989947.1\|21123_21933_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_171269897.1\|21934_23824_-	lipopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_171269898.1\|23869_24415_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	4.9e-52	58.0
WP_052815420.1\|24446_25325_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	4.8e-105	64.1
WP_080989944.1\|25328_26234_-	dTDP-4-dehydrorhamnose reductase	NA	NA	NA	NA
WP_052815419.1\|26233_27319_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.3e-96	52.2
WP_005342491.1\|27852_28803_-\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_171269899.1\|29448_30123_+	response regulator	W8CYM9	Bacillus_phage	2.8e-28	34.6
WP_171269900.1\|30122_31505_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_039041241.1\|31880_32849_-	glucokinase	NA	NA	NA	NA
WP_167332173.1\|33197_34052_+	transcriptional regulator HexR	NA	NA	NA	NA
WP_005324189.1\|34212_35652_+	pyruvate kinase	NA	NA	NA	NA
WP_171269901.1\|35718_36762_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_171269902.1\|36777_39840_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.7e-70	25.2
WP_171269903.1\|40001_42326_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_005324182.1\|42373_43027_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_161506976.1\|43495_44236_+	phosphatase	NA	NA	NA	NA
WP_171270000.1\|44862_45552_-	RNA ligase family protein	A0A2H4UUE0	Bodo_saltans_virus	3.0e-06	43.5
WP_171269904.1\|45566_46094_-	hypothetical protein	NA	NA	NA	NA
WP_171269905.1\|46090_47302_-	DUF3696 domain-containing protein	NA	NA	NA	NA
WP_171269906.1\|48269_49406_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_099992639.1\|50028_51045_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	9.8e-187	99.7
WP_004576012.1\|51805_53224_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205574.1\|53234_53660_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206863.1\|53717_54857_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_005328266.1\|55060_55396_+	addiction module protein	A0A141GEX6	Brucella_phage	2.0e-11	46.4
WP_041206074.1\|55401_55716_+	DNA-binding protein	NA	NA	NA	NA
WP_005328262.1\|56281_56434_-	hypothetical protein	NA	NA	NA	NA
WP_041206077.1\|57206_57962_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.6e-59	51.5
WP_041206078.1\|57976_59518_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	2.5e-125	46.4
WP_041206863.1\|60168_61308_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_099369027.1\|61426_62443_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_171270001.1\|62564_62990_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.8e-23	46.9

DBSCAN-SWA_2

108925 : 184861

Escherichia_phage(13.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205253.1\|108925_110263_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041205380.1\|110304_110730_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	3.9e-12	40.0
WP_005326910.1\|111007_112654_+	response regulator	NA	NA	NA	NA
WP_041206863.1\|112717_113857_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041205574.1\|113914_114340_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041205379.1\|114451_115414_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_041205378.1\|115639_116446_+	exodeoxyribonuclease III	A0A0N9QXX6	Chrysochromulina_ericina_virus	5.7e-12	27.5
WP_171268788.1\|116644_117139_+	hypothetical protein	NA	NA	NA	NA
WP_171268787.1\|117428_118937_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_171268786.1\|119010_122139_+	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_171268785.1\|122183_122561_+	copper-binding protein	NA	NA	NA	NA
WP_171268784.1\|122634_124329_-	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_103261429.1\|124505_125519_-	lipoate--protein ligase	NA	NA	NA	NA
WP_171268783.1\|125930_128375_+	diguanylate cyclase	G3MA91	Bacillus_virus	4.8e-22	36.2
WP_171269913.1\|128408_131591_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_171270004.1\|131583_132654_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_171269914.1\|132695_133154_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_171269915.1\|133167_133581_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_171269916.1\|133580_133895_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_043132505.1\|133987_134173_+	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_041205364.1\|134538_134943_+	hypothetical protein	NA	NA	NA	NA
WP_042649827.1\|135165_135894_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.5e-11	39.3
WP_171277300.1\|135856_136990_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_171268777.1\|137017_138433_-	sucrose-6-phosphate hydrolase	NA	NA	NA	NA
WP_005330304.1\|138432_139797_-	PTS sucrose transporter subunit IIBC	NA	NA	NA	NA
WP_171269917.1\|139868_140846_-	aminoimidazole riboside kinase	NA	NA	NA	NA
WP_171269918.1\|140958_142443_-	carbohydrate porin	NA	NA	NA	NA
WP_005330311.1\|142705_143842_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	3.1e-24	35.1
WP_041205360.1\|144095_146021_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.1e-151	51.0
WP_025327678.1\|146355_146931_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_005332581.1\|147194_148079_+	NAD(+) kinase	NA	NA	NA	NA
WP_042649835.1\|149525_151190_+	DNA repair protein RecN	NA	NA	NA	NA
WP_171269919.1\|151725_152607_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_171269920.1\|153003_153444_+	universal stress protein	NA	NA	NA	NA
WP_171268771.1\|153690_154854_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_171269921.1\|154850_156890_+	MacB family efflux pump subunit	G9BWD6	Planktothrix_phage	2.4e-35	39.9
WP_171269452.1\|156949_158284_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_171268769.1\|158415_159222_+	siderophore-interacting protein	NA	NA	NA	NA
WP_171269922.1\|159480_160587_+	3-deoxy-7-phosphoheptulonate synthase	A0A218MA87	Escherichia_phage	2.7e-81	47.3
WP_005332615.1\|161062_161470_-	H-NS histone family protein	NA	NA	NA	NA
WP_043132497.1\|161878_162823_-	DNA-binding transcriptional regulator DsdC	NA	NA	NA	NA
WP_171269923.1\|163053_164391_+	D-serine transporter DsdX	NA	NA	NA	NA
WP_171269924.1\|164408_165740_+	D-serine ammonia-lyase	NA	NA	NA	NA
WP_005328937.1\|166070_166247_+	hypothetical protein	NA	NA	NA	NA
WP_005328927.1\|166344_167598_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.6e-13	72.2
WP_171268764.1\|167795_168671_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_139750679.1\|168800_170000_+	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_139750680.1\|170187_170736_+	YgjV family protein	NA	NA	NA	NA
WP_005328920.1\|170875_171025_-	hypothetical protein	NA	NA	NA	NA
WP_171269926.1\|173781_176106_-	Ig-like domain-containing protein	J9Q6D6	Salmonella_phage	6.7e-05	27.6
WP_171269265.1\|177214_178246_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_043132489.1\|178285_178729_+	CopD family protein	NA	NA	NA	NA
WP_171269927.1\|179064_179928_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041206012.1\|180289_181852_+\|transposase	IS21-like element ISAs28 family transposase	K4I413	Acidithiobacillus_phage	3.3e-125	46.2
WP_021141277.1\|181875_182631_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.4
WP_171269928.1\|183913_184861_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	3.1e-41	35.4

DBSCAN-SWA_3

305992 : 352852

Bodo_saltans_virus(12.5%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205257.1\|305992_307000_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	7.8e-19	29.4
WP_171268702.1\|307221_307977_+	YciK family oxidoreductase	NA	NA	NA	NA
WP_005331279.1\|308064_308949_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_171268701.1\|309017_310190_-	MFS transporter	NA	NA	NA	NA
WP_171268700.1\|310353_311496_+	putative C-S lyase	NA	NA	NA	NA
WP_171268699.1\|311847_313170_+	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_163147847.1\|313248_314157_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_025326213.1\|314327_315584_+	adenylosuccinate synthetase	A0A2R8FF47	Brazilian_cedratvirus	6.5e-47	31.5
WP_171268698.1\|315853_316390_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_171268697.1\|316401_317205_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_171268696.1\|317389_319870_+	alpha-glucosidase	NA	NA	NA	NA
WP_171269936.1\|319944_321144_-\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_171268694.1\|321258_322578_+	peptidoglycan DD-metalloendopeptidase family protein	A0A1P8BKT8	Lactococcus_phage	1.0e-18	48.7
WP_171268693.1\|322634_323759_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_171268692.1\|323850_324132_-	hypothetical protein	NA	NA	NA	NA
WP_010676219.1\|324673_325771_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_005327996.1\|327621_329040_-\|transposase	IS66-like element ISUnCu16 family transposase	NA	NA	NA	NA
WP_171269447.1\|330225_330501_-	hypothetical protein	NA	NA	NA	NA
WP_171268691.1\|331000_332992_-	transketolase	NA	NA	NA	NA
WP_025326202.1\|333333_334485_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.7e-129	62.6
WP_171268690.1\|334553_335093_+\|protease	SprT family zinc-dependent metalloprotease	A0A060AI19	Cronobacter_phage	5.9e-05	28.0
WP_171268689.1\|335166_335865_+	endonuclease	NA	NA	NA	NA
WP_171268688.1\|335934_336666_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_163136244.1\|336717_337668_+	glutathione synthase	NA	NA	NA	NA
WP_171268687.1\|337863_338418_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_025326196.1\|338738_339161_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_171269446.1\|339188_340202_-	HTH-type transcriptional regulator YidZ	NA	NA	NA	NA
WP_171268686.1\|340220_341393_-	MFS transporter	NA	NA	NA	NA
WP_041205051.1\|341811_343149_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041205244.1\|344501_345941_-	alanine:cation symporter family protein	NA	NA	NA	NA
WP_041206846.1\|346685_347636_+	transaldolase	A0A127KNC6	Cyanophage	2.7e-13	30.7
WP_025326190.1\|347829_348009_+	DUF3545 family protein	NA	NA	NA	NA
WP_041205240.1\|348105_348654_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_171268685.1\|348838_349525_-	uracil-DNA glycosylase	A0A0A7D9F8	Equid_alphaherpesvirus	4.3e-53	49.3
WP_005330139.1\|350116_350497_+	autonomous glycyl radical cofactor GrcA	A0A219YAN3	Aeromonas_phage	2.8e-30	59.5
WP_042650017.1\|351808_352852_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

701239 : 777964

Bacillus_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005342491.1\|701239_702190_+\|transposase	IS1595-like element ISKpn3 family transposase	NA	NA	NA	NA
WP_099368923.1\|703261_704278_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	3.7e-186	99.4
WP_042648917.1\|705350_705956_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_042648916.1\|706101_706692_+	MliC family protein	NA	NA	NA	NA
WP_042648915.1\|706753_708262_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_042648914.1\|708536_709463_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_042648913.1\|709642_710884_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_042648912.1\|711017_712217_-	acetate kinase	NA	NA	NA	NA
WP_042648911.1\|712736_713207_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_025325894.1\|713507_714614_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_042648919.1\|714833_715385_-	ribosomal protein S5-alanine N-acetyltransferase	NA	NA	NA	NA
WP_025325892.1\|715446_716007_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_042648910.1\|716355_718125_+	M4 family metallopeptidase	NA	NA	NA	NA
WP_042648909.1\|718171_719071_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042648908.1\|719279_720473_+	multidrug efflux MFS transporter MdtH	NA	NA	NA	NA
WP_171277302.1\|720675_738792_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_042649094.1\|739015_740677_-	putative transporter	NA	NA	NA	NA
WP_042649093.1\|740794_741430_-	hemolysin III family protein	NA	NA	NA	NA
WP_042649092.1\|741664_743197_+	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_042649091.1\|743333_743885_+	septation protein A	NA	NA	NA	NA
WP_025325883.1\|743909_744206_+	YciI family protein	NA	NA	NA	NA
WP_042649090.1\|744295_745051_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_042649089.1\|745216_745537_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_042649088.1\|745630_746542_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.0e-61	45.9
WP_042649087.1\|746755_748153_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.4e-79	38.8
WP_042649086.1\|748225_749197_-	response regulator	NA	NA	NA	NA
WP_042649095.1\|749509_750184_+	hypothetical protein	NA	NA	NA	NA
WP_042649085.1\|750250_751105_+	ATP-binding protein	A0A1B1P8D0	Bacillus_phage	4.8e-09	28.4
WP_042649084.1\|751232_751868_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_042649083.1\|751946_753146_-	ABC transporter permease	NA	NA	NA	NA
WP_042649082.1\|753142_754285_-	ABC transporter permease	NA	NA	NA	NA
WP_041206813.1\|754284_755262_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005327981.1\|755362_756721_-	TolC family protein	NA	NA	NA	NA
WP_119196704.1\|757532_758801_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.3e-60	33.7
WP_119196703.1\|758805_762063_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_119196702.1\|762063_763341_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_119196699.1\|763337_765365_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_005309538.1\|766173_766470_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_042649080.1\|767027_768452_+	hypothetical protein	NA	NA	NA	NA
WP_042649079.1\|768650_769847_-	J domain-containing protein	NA	NA	NA	NA
WP_042649078.1\|770005_770656_-	hypothetical protein	NA	NA	NA	NA
WP_158196733.1\|770639_771971_-	AAA family ATPase	C7BGE8	Burkholderia_phage	8.2e-08	30.6
WP_171269942.1\|772258_772474_+	hypothetical protein	NA	NA	NA	NA
WP_171268592.1\|772750_773506_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.2e-58	50.6
WP_158196731.1\|773520_775062_-\|transposase	IS21-like element ISAs29 family transposase	K4I413	Acidithiobacillus_phage	1.3e-129	47.4
WP_158196730.1\|775238_775466_-	hypothetical protein	NA	NA	NA	NA
WP_158196729.1\|775452_776961_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_158196728.1\|777214_777964_+\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	7.3e-14	36.9

DBSCAN-SWA_5

786244 : 839609

uncultured_Caudovirales_phage(33.33%)

transposase,integrase,tRNA

attL 778926:778942|attR 843962:843978

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
778926:778942	attL	NA	NA	NA	NA
WP_171269945.1\|786244_787306_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_042650017.1\|788277_789321_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_021141311.1\|790746_791883_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_171269946.1\|792641_792815_+	hypothetical protein	NA	NA	NA	NA
WP_171268589.1\|792852_794817_+	GGDEF domain-containing protein	G3MA91	Bacillus_virus	3.6e-20	35.6
WP_158196722.1\|795536_796965_+\|transposase	IS66-like element ISAeme23 family transposase	NA	NA	NA	NA
WP_042054148.1\|797164_797500_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
WP_158196721.1\|797574_797889_-	hypothetical protein	NA	NA	NA	NA
WP_158196720.1\|797978_798275_-	hypothetical protein	NA	NA	NA	NA
WP_158196719.1\|798307_798649_-	hypothetical protein	NA	NA	NA	NA
WP_029303521.1\|798650_799193_-	hypothetical protein	NA	NA	NA	NA
WP_158196718.1\|799272_799635_-	hypothetical protein	NA	NA	NA	NA
WP_158196717.1\|799631_799847_-	hypothetical protein	NA	NA	NA	NA
WP_158196716.1\|799843_800353_-	hypothetical protein	NA	NA	NA	NA
WP_158198333.1\|800469_800718_-	hypothetical protein	NA	NA	NA	NA
WP_158196715.1\|800832_801024_-	hypothetical protein	NA	NA	NA	NA
WP_158196714.1\|801020_801518_-	DNA repair protein RadC	NA	NA	NA	NA
WP_158196713.1\|801885_802314_-	hypothetical protein	NA	NA	NA	NA
WP_171269439.1\|802324_802750_-	DUF2787 family protein	NA	NA	NA	NA
WP_158196711.1\|802785_803349_-	lecithin retinol acyltransferase family protein	NA	NA	NA	NA
WP_158196710.1\|803436_804111_-	hypothetical protein	NA	NA	NA	NA
WP_042034774.1\|804122_804275_-	hypothetical protein	NA	NA	NA	NA
WP_158196709.1\|804286_804640_-	hypothetical protein	NA	NA	NA	NA
WP_024945142.1\|804921_805266_+	helix-turn-helix transcriptional regulator	A0A2H4J5G9	uncultured_Caudovirales_phage	1.5e-06	34.3
WP_171269947.1\|805412_806387_-	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_021137981.1\|806804_807017_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.8e-05	35.9
WP_158196706.1\|807403_808453_+	hypothetical protein	NA	NA	NA	NA
WP_010674210.1\|808584_810198_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_171270005.1\|810314_810668_+	H-NS histone family protein	NA	NA	NA	NA
WP_158196703.1\|811723_812941_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JB45	uncultured_Caudovirales_phage	1.6e-103	49.9
WP_042649676.1\|813187_813820_-	LysE family translocator	NA	NA	NA	NA
WP_025328177.1\|819884_820235_-	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	6.7e-26	49.5
WP_042649482.1\|820324_821017_-	hypothetical protein	NA	NA	NA	NA
WP_042649481.1\|821104_822499_-	H(+)/Cl(-) exchange transporter ClcA	NA	NA	NA	NA
WP_042649480.1\|822721_824008_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_042649483.1\|824218_825043_+	hypothetical protein	NA	NA	NA	NA
WP_042649479.1\|825081_826002_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_042649478.1\|826248_826965_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_042649477.1\|827174_827690_+	DUF2937 family protein	NA	NA	NA	NA
WP_042649476.1\|827753_828635_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042649475.1\|828793_829186_+	multidrug transporter	NA	NA	NA	NA
WP_042649474.1\|829173_829494_+	ligand-binding protein SH3	NA	NA	NA	NA
WP_041205253.1\|829593_830931_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_042650422.1\|831016_831427_-	VOC family protein	NA	NA	NA	NA
WP_005327576.1\|831469_833791_-	penicillin-binding protein 1B	NA	NA	NA	NA
WP_042650421.1\|834055_836503_-	ATP-dependent helicase HrpB	A0A0G2Y9F4	Acanthamoeba_polyphaga_mimivirus	2.9e-27	27.8
WP_005327573.1\|836739_837285_+	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_005327571.1\|837281_838019_+	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_005329052.1\|838144_838594_+	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_041206812.1\|838706_839609_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
843962:843978	attR	NA	NA	NA	NA

DBSCAN-SWA_6

884454 : 898295

Acidithiobacillus_phage(20.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042061740.1\|884454_886017_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	8.2e-124	46.2
WP_024945936.1\|886042_886798_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.9e-52	45.4
WP_081805626.1\|888319_890185_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6
WP_005331907.1\|890398_892186_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.0e-74	41.4
WP_005331908.1\|892274_892718_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.0e-27	48.6
WP_005309452.1\|892733_892949_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_005331910.1\|893128_894142_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.1e-108	58.6
WP_005331913.1\|894229_895213_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	4.9e-34	33.7
WP_041205045.1\|895259_896324_-	LysM peptidoglycan-binding domain-containing protein	A0A0A7NU10	Lactobacillus_phage	4.9e-11	36.2
WP_041205044.1\|896333_896915_-	DedA family protein	NA	NA	NA	NA
WP_005332743.1\|896911_897529_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.4e-34	46.4
WP_042648740.1\|897533_898295_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.3e-70	53.4

DBSCAN-SWA_7

1323544 : 1363794

Bacillus_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|1323544_1324681_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_042650017.1\|1325291_1326335_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_005307999.1\|1333218_1333602_-	50S ribosomal protein L17	NA	NA	NA	NA
WP_005307997.1\|1333645_1334635_-	DNA-directed RNA polymerase subunit alpha	NA	NA	NA	NA
WP_010672568.1\|1334660_1335281_-	30S ribosomal protein S4	NA	NA	NA	NA
WP_005319702.1\|1335320_1335710_-	30S ribosomal protein S11	NA	NA	NA	NA
WP_005307991.1\|1335724_1336081_-	30S ribosomal protein S13	NA	NA	NA	NA
WP_005319705.1\|1336220_1336334_-	50S ribosomal protein L36	NA	NA	NA	NA
WP_005307989.1\|1336361_1337690_-	preprotein translocase subunit SecY	NA	NA	NA	NA
WP_025325390.1\|1337698_1338136_-	50S ribosomal protein L15	NA	NA	NA	NA
WP_005307985.1\|1338138_1338318_-	50S ribosomal protein L30	NA	NA	NA	NA
WP_005340605.1\|1338324_1338825_-	30S ribosomal protein S5	NA	NA	NA	NA
WP_033130012.1\|1338839_1339193_-	50S ribosomal protein L18	NA	NA	NA	NA
WP_025325388.1\|1339202_1339736_-	50S ribosomal protein L6	NA	NA	NA	NA
WP_042648861.1\|1339749_1340142_-	30S ribosomal protein S8	NA	NA	NA	NA
WP_005331161.1\|1340161_1340467_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_005331162.1\|1340477_1341017_-	50S ribosomal protein L5	NA	NA	NA	NA
WP_025325387.1\|1341030_1341348_-	50S ribosomal protein L24	NA	NA	NA	NA
WP_005307975.1\|1341359_1341728_-	50S ribosomal protein L14	NA	NA	NA	NA
WP_005307966.1\|1341876_1342125_-	30S ribosomal protein S17	NA	NA	NA	NA
WP_005307965.1\|1342124_1342316_-	50S ribosomal protein L29	NA	NA	NA	NA
WP_005307963.1\|1342315_1342729_-	50S ribosomal protein L16	NA	NA	NA	NA
WP_005331168.1\|1342742_1343456_-	30S ribosomal protein S3	NA	NA	NA	NA
WP_005319741.1\|1343459_1343804_-	50S ribosomal protein L22	NA	NA	NA	NA
WP_005307960.1\|1343814_1344093_-	30S ribosomal protein S19	NA	NA	NA	NA
WP_005331177.1\|1344115_1344937_-	50S ribosomal protein L2	NA	NA	NA	NA
WP_005331199.1\|1344952_1345255_-	50S ribosomal protein L23	NA	NA	NA	NA
WP_025325386.1\|1345251_1345857_-	50S ribosomal protein L4	NA	NA	NA	NA
WP_025325385.1\|1345874_1346507_-	50S ribosomal protein L3	NA	NA	NA	NA
WP_005307944.1\|1346529_1346841_-	30S ribosomal protein S10	NA	NA	NA	NA
WP_042648862.1\|1347197_1348112_+	DMT family transporter	NA	NA	NA	NA
WP_042648863.1\|1348149_1349460_-	two-component system sensor histidine kinase EnvZ	W8CYF6	Bacillus_phage	1.2e-11	23.1
WP_005328510.1\|1349456_1350176_-	two-component system response regulator OmpR	W8CYM9	Bacillus_phage	5.7e-32	34.2
WP_161646994.1\|1350675_1351953_+	hypothetical protein	NA	NA	NA	NA
WP_004576012.1\|1352417_1353836_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_171269951.1\|1353891_1354677_+	hypothetical protein	NA	NA	NA	NA
WP_161646995.1\|1354864_1355758_-	hypothetical protein	NA	NA	NA	NA
WP_171270006.1\|1356712_1357747_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	8.0e-27	31.5
WP_171269952.1\|1357743_1359018_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_004099020.1\|1359174_1359546_+	hypothetical protein	NA	NA	NA	NA
WP_011191342.1\|1359863_1361132_+\|transposase	IS4-like element ISApu1 family transposase	NA	NA	NA	NA
WP_171269953.1\|1361509_1362118_-	HNH endonuclease	NA	NA	NA	NA
WP_171269954.1\|1362202_1362418_-	hypothetical protein	NA	NA	NA	NA
WP_021141311.1\|1362657_1363794_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2264655 : 2323369

Diachasmimorpha_longicaudata_entomopoxvirus(12.5%)

transposase,integrase,protease,tRNA

attL 2294262:2294275|attR 2323299:2323312

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042649784.1\|2264655_2265642_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_041206428.1\|2265778_2266237_+	zinc uptake transcriptional repressor Zur	NA	NA	NA	NA
WP_005332255.1\|2266226_2266688_+	chemotaxis protein CheX	NA	NA	NA	NA
WP_005332257.1\|2266693_2266921_+	hypothetical protein	NA	NA	NA	NA
WP_041207086.1\|2267009_2268317_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_042649785.1\|2268508_2269219_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_042649786.1\|2269347_2270571_+	ATP-dependent RNA helicase SrmB	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	3.5e-45	28.8
WP_042649787.1\|2270756_2271530_-	peroxide stress protein YaaA	NA	NA	NA	NA
WP_171269317.1\|2272697_2273732_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_171269316.1\|2273771_2274473_+	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_171269315.1\|2274632_2275460_+	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_025325667.1\|2275483_2276035_+	YggT family protein	NA	NA	NA	NA
WP_043128939.1\|2276034_2276343_+	YggU family protein	NA	NA	NA	NA
WP_041206420.1\|2276347_2276767_+	DUF4426 domain-containing protein	NA	NA	NA	NA
WP_171269314.1\|2276846_2277677_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_005332293.1\|2277871_2278168_-	hypothetical protein	NA	NA	NA	NA
WP_005332296.1\|2278218_2278593_-	YacL family protein	NA	NA	NA	NA
WP_171269313.1\|2278941_2280057_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_025325674.1\|2280176_2281439_+	GntP family permease	NA	NA	NA	NA
WP_171269532.1\|2281448_2282582_+	glycerate kinase	W6LM47	Streptococcus_phage	7.1e-45	39.0
WP_171269311.1\|2282784_2283348_+	NnrU family protein	NA	NA	NA	NA
WP_171269310.1\|2283407_2283944_+	glutathione peroxidase	NA	NA	NA	NA
WP_042649797.1\|2284026_2284962_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_171269533.1\|2285144_2286341_+	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_171269308.1\|2286851_2287346_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.7e-22	51.9
WP_171269307.1\|2287373_2287790_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_005332325.1\|2287991_2288330_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_005332327.1\|2288559_2289570_+	Fe(3+) ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_171269306.1\|2289609_2291235_+	iron ABC transporter permease	NA	NA	NA	NA
WP_139751234.1\|2291307_2292342_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	3.7e-24	32.1
WP_005332333.1\|2292423_2293329_+	Dyp-type peroxidase	NA	NA	NA	NA
WP_005308670.1\|2293407_2293878_-	transcriptional regulator ArgR	NA	NA	NA	NA
WP_171269305.1\|2294078_2294819_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.3e-22	34.3
2294262:2294275	attL	NA	NA	NA	NA
WP_005332335.1\|2294843_2295581_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005332336.1\|2295584_2296235_+	arginine ABC transporter permease ArtQ	NA	NA	NA	NA
WP_042649806.1\|2296237_2296900_+	arginine ABC transporter permease ArtM	NA	NA	NA	NA
WP_041206414.1\|2297142_2298078_+	malate dehydrogenase	NA	NA	NA	NA
WP_171277299.1\|2298232_2298472_+	hypothetical protein	NA	NA	NA	NA
WP_171269304.1\|2299188_2300382_-	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_041206413.1\|2300493_2300961_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_041206412.1\|2300992_2302273_-	DUF21 domain-containing protein	NA	NA	NA	NA
WP_171269303.1\|2302313_2303105_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_171269302.1\|2303391_2304771_+	signal recognition particle protein	NA	NA	NA	NA
WP_042649810.1\|2304950_2305199_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_005332346.1\|2305223_2305745_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_041206410.1\|2305779_2306529_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_005313505.1\|2306561_2306909_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_171269301.1\|2307014_2307344_-	1,4-alpha-glucan branching protein	NA	NA	NA	NA
WP_042649812.1\|2307427_2308102_-	DNA mismatch repair endonuclease MutH	NA	NA	NA	NA
WP_041206409.1\|2308836_2309364_+	RNA pyrophosphohydrolase	NA	NA	NA	NA
WP_171269300.1\|2309377_2311657_+	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	1.2e-11	28.0
WP_041207083.1\|2311724_2312552_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_042649815.1\|2313201_2314416_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_010674210.1\|2314617_2316231_+\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_171269299.1\|2316296_2318612_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_021141270.1\|2318608_2320624_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_021141269.1\|2320620_2321103_+	hypothetical protein	NA	NA	NA	NA
WP_042650619.1\|2321099_2321933_+	thymidylate synthase	E5DV96	Deep-sea_thermophilic_phage	3.2e-95	61.0
WP_001310555.1\|2322352_2323369_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	9.8e-187	99.7
2323299:2323312	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3432989 : 3493173

Escherichia_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171269628.1\|3432989_3433955_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_042650017.1\|3434018_3435062_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_005331601.1\|3435463_3435781_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_171269629.1\|3435941_3436952_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_171269630.1\|3437297_3439559_-	LTA synthase family protein	NA	NA	NA	NA
WP_042648302.1\|3439809_3440904_+	hypothetical protein	NA	NA	NA	NA
WP_005327565.1\|3441040_3442393_-	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_148304685.1\|3442457_3442637_+	hypothetical protein	NA	NA	NA	NA
WP_042648311.1\|3442810_3444139_-	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_005327561.1\|3444391_3445024_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_042648312.1\|3445290_3445626_-	DUF3802 family protein	NA	NA	NA	NA
WP_171268989.1\|3445637_3446174_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_042648304.1\|3446179_3446551_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_171269631.1\|3446659_3447469_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_171269632.1\|3447507_3448413_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_171269633.1\|3448548_3450246_+	L-lactate permease	NA	NA	NA	NA
WP_171269979.1\|3450259_3451036_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_171269634.1\|3451028_3452465_+	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_171269635.1\|3452466_3453111_+	LUD domain-containing protein	NA	NA	NA	NA
WP_171269636.1\|3453110_3455903_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_171269637.1\|3456032_3456896_-	class A beta-lactamase	A0A077SL40	Escherichia_phage	1.5e-50	41.3
WP_171269638.1\|3458458_3458998_-	hypothetical protein	NA	NA	NA	NA
WP_010674210.1\|3458969_3460583_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_171269639.1\|3460654_3461197_-	hypothetical protein	NA	NA	NA	NA
WP_099368881.1\|3461241_3462258_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_171269640.1\|3462366_3463059_-	hypothetical protein	NA	NA	NA	NA
WP_171269980.1\|3463774_3464827_-	carotenoid 1,2-hydratase	NA	NA	NA	NA
WP_171269641.1\|3465012_3467433_-	ABC transporter permease	NA	NA	NA	NA
WP_171269642.1\|3467454_3468135_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-29	35.0
WP_171269643.1\|3468287_3468761_+	DUF4357 domain-containing protein	NA	NA	NA	NA
WP_171269644.1\|3468886_3470314_+	sodium:proton antiporter NhaD	NA	NA	NA	NA
WP_171269981.1\|3470343_3470910_+	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_171269645.1\|3470990_3472193_-	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	1.2e-21	25.4
WP_171269646.1\|3472309_3473956_-	hypothetical protein	NA	NA	NA	NA
WP_171269647.1\|3474043_3475306_-	hypothetical protein	NA	NA	NA	NA
WP_171269982.1\|3475411_3475984_-	hypothetical protein	NA	NA	NA	NA
WP_171269648.1\|3476096_3477518_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_171269649.1\|3477597_3478422_-	FTR1 family protein	NA	NA	NA	NA
WP_005327423.1\|3481394_3481844_-	hypothetical protein	NA	NA	NA	NA
WP_171269651.1\|3481967_3482453_-	YqhA family protein	NA	NA	NA	NA
WP_171269653.1\|3483252_3484053_-	transglutaminase family protein	NA	NA	NA	NA
WP_005327429.1\|3484049_3484976_-	alpha-E domain-containing protein	NA	NA	NA	NA
WP_171269654.1\|3484969_3486406_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_171269655.1\|3486923_3487295_-	hypothetical protein	NA	NA	NA	NA
WP_171269656.1\|3487428_3489165_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	2.2e-29	23.3
WP_010676219.1\|3490388_3491486_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_099368881.1\|3492156_3493173_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4

DBSCAN-SWA_10

3583673 : 3605440

Aeromonas_phage(21.05%)

integrase,terminase,capsid,holin,portal,head,protease

attL 3576770:3576784|attR 3609644:3609658

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3576770:3576784	attL	NA	NA	NA	NA
WP_171269702.1\|3583673_3584867_+\|integrase	site-specific integrase	K7P7J2	Enterobacteria_phage	1.0e-86	45.3
WP_102948335.1\|3584813_3585008_-	hypothetical protein	NA	NA	NA	NA
WP_102948336.1\|3585016_3585433_-	hypothetical protein	NA	NA	NA	NA
WP_171269703.1\|3587120_3587651_-	class I SAM-dependent methyltransferase	A0A0N7IRF6	Acinetobacter_phage	4.5e-58	59.9
WP_171269704.1\|3587647_3587992_-	DUF4406 domain-containing protein	A0A1I9KFD3	Aeromonas_phage	3.2e-25	64.8
WP_171269705.1\|3588182_3589391_-	hypothetical protein	A0A291AUQ1	Sinorhizobium_phage	6.4e-68	36.2
WP_171269706.1\|3589380_3590445_-	nucleoid-associated protein	A0A291AUQ0	Sinorhizobium_phage	2.5e-63	42.1
WP_080944298.1\|3590553_3591204_-	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	3.5e-44	48.7
WP_045525005.1\|3591291_3591477_+	hypothetical protein	H9C161	Pectobacterium_phage	3.6e-07	46.3
WP_171269986.1\|3591503_3591995_+	phage regulatory CII family protein	NA	NA	NA	NA
WP_171269987.1\|3592072_3592276_+	hypothetical protein	NA	NA	NA	NA
WP_171269707.1\|3592265_3592532_+	hypothetical protein	NA	NA	NA	NA
WP_171269708.1\|3592584_3593595_+	hypothetical protein	A0A1I9KG10	Aeromonas_phage	5.2e-31	45.7
WP_171269709.1\|3593572_3594058_+	hypothetical protein	NA	NA	NA	NA
WP_171269710.1\|3594057_3594339_+	hypothetical protein	NA	NA	NA	NA
WP_102948395.1\|3594424_3595126_+	phage antirepressor KilAC domain-containing protein	A0A1I9KFA9	Aeromonas_phage	1.5e-61	57.3
WP_005324004.1\|3595122_3595320_+	DUF3283 family protein	NA	NA	NA	NA
WP_171269988.1\|3595334_3596309_+	DUF968 domain-containing protein	R9TRM9	Vibrio_phage	3.1e-28	34.5
WP_171269711.1\|3596295_3596682_+	RusA family crossover junction endodeoxyribonuclease	A0A0H5AUD2	Pseudomonas_phage	3.1e-24	53.9
WP_171269712.1\|3596671_3597307_+	antitermination protein	NA	NA	NA	NA
WP_171269713.1\|3597545_3597869_+\|holin	phage holin, lambda family	A5X9I3	Aeromonas_virus	4.9e-23	58.5
WP_171269714.1\|3597932_3598379_+	structural protein P5	A0A0D4DAE2	Escherichia_phage	5.7e-38	55.7
WP_171269715.1\|3598386_3598656_+	hypothetical protein	NA	NA	NA	NA
WP_171269716.1\|3598703_3598913_+	hypothetical protein	NA	NA	NA	NA
WP_171269717.1\|3599087_3599294_+	hypothetical protein	NA	NA	NA	NA
WP_171269718.1\|3599368_3599734_+	HNH endonuclease	A0A1P8DTD1	Proteus_phage	7.7e-33	57.3
WP_171269719.1\|3600000_3600438_+\|terminase	phage terminase small subunit P27 family	A0A2D1GNP3	Pseudomonas_phage	1.1e-06	31.4
WP_171269720.1\|3600437_3602183_+\|terminase	terminase large subunit	G3EN96	Psychrobacter_phage	2.9e-162	52.9
WP_171269721.1\|3602175_3602364_+	hypothetical protein	NA	NA	NA	NA
WP_171269722.1\|3602338_3603586_+\|portal	phage portal protein	A0A1J0GUY8	Halomonas_phage	2.7e-106	52.2
WP_171269723.1\|3603575_3604172_+\|head,protease	HK97 family phage prohead protease	A0A1J0GUZ0	Halomonas_phage	5.8e-54	56.7
WP_171269724.1\|3604234_3605440_+\|capsid	phage major capsid protein	Q8SBH8	Shigella_phage	2.0e-98	48.0
3609644:3609658	attR	NA	NA	NA	NA

DBSCAN-SWA_11

3608856 : 3621520

Aeromonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171269732.1\|3608856_3611157_+	hypothetical protein	A0A2L0V160	Salmonella_phage	2.4e-23	47.5
WP_171269733.1\|3611166_3611781_+	hypothetical protein	Q7Y3Z8	Yersinia_phage	2.2e-48	48.0
WP_171269734.1\|3611777_3612365_+	hypothetical protein	S4TND4	Salmonella_phage	5.0e-42	45.4
WP_171269735.1\|3612367_3612769_+	hypothetical protein	A0A2I6PG15	Plesiomonas_phage	1.4e-27	47.4
WP_171277305.1\|3612768_3617799_+	DUF1983 domain-containing protein	Q7Y3Z3	Yersinia_phage	1.0e-10	41.2
WP_171269737.1\|3617863_3619420_+	hypothetical protein	A0A1I9KFH7	Aeromonas_phage	1.4e-192	65.6
WP_043162866.1\|3619480_3619825_+	diversity-generating retroelement protein Avd	A0A1I9KFC4	Aeromonas_phage	4.2e-57	99.1
WP_139751053.1\|3620066_3620348_+	hypothetical protein	A0A1I9KG33	Aeromonas_phage	4.3e-44	94.6
WP_171269738.1\|3620803_3621520_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	3.3e-80	61.0

DBSCAN-SWA_12

3760293 : 3809365

Escherichia_phage(22.22%)

transposase,integrase,protease

attL 3797508:3797526|attR 3810435:3810453

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005324108.1\|3760293_3761568_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.4e-128	56.7
WP_005324110.1\|3761708_3764063_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.5e-225	53.5
WP_005315375.1\|3764303_3764576_+	DNA-binding protein HU-beta	A7KV42	Bacillus_phage	5.0e-21	61.8
WP_171269795.1\|3764725_3766639_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_005324115.1\|3766940_3768533_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	1.4e-57	27.6
WP_042650381.1\|3768744_3770400_-	cation acetate symporter	NA	NA	NA	NA
WP_005324119.1\|3770396_3770708_-	DUF485 domain-containing protein	NA	NA	NA	NA
WP_043130766.1\|3770815_3771442_-	3'-5' exonuclease	NA	NA	NA	NA
WP_171269796.1\|3771444_3773232_-	cyclic nucleotide-binding/CBS domain-containing protein	NA	NA	NA	NA
WP_005324126.1\|3773390_3774197_+	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_041205868.1\|3774271_3775771_-	alanine:cation symporter family protein	NA	NA	NA	NA
WP_043130760.1\|3776075_3776507_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_043130757.1\|3776526_3777336_+	zinc-dependent peptidase	NA	NA	NA	NA
WP_005315399.1\|3777414_3778011_-	hypothetical protein	NA	NA	NA	NA
WP_081934506.1\|3778771_3781675_-	DUF748 domain-containing protein	NA	NA	NA	NA
WP_041206952.1\|3781943_3782357_-	MerR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_043130754.1\|3782429_3783401_-	hydroxymethylglutaryl-CoA lyase	A0A1V0SKU2	Klosneuvirus	1.8e-44	35.7
WP_043130753.1\|3783397_3785359_-	methylcrotonoyl-CoA carboxylase	NA	NA	NA	NA
WP_043130750.1\|3785486_3786341_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_171269797.1\|3788040_3789189_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_043130742.1\|3789465_3790977_+	CoA-acylating methylmalonate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_171269798.1\|3791057_3792215_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_042650368.1\|3792329_3793127_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_171269799.1\|3793119_3794229_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_043130732.1\|3794288_3795209_+	3-hydroxyisobutyrate dehydrogenase	NA	NA	NA	NA
WP_043130731.1\|3795270_3796032_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	6.1e-08	24.7
WP_043130728.1\|3796419_3797856_+	arginine-ornithine antiporter	NA	NA	NA	NA
3797508:3797526	attL	NA	NA	NA	NA
WP_043130725.1\|3797948_3798737_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_043130722.1\|3799033_3800194_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_171269800.1\|3800322_3800652_+	hypothetical protein	NA	NA	NA	NA
WP_171269801.1\|3800727_3801720_-\|transposase	IS5 family transposase	A0A077SK28	Escherichia_phage	1.8e-153	81.4
WP_171269802.1\|3801987_3802389_+	abortive infection family protein	NA	NA	NA	NA
WP_099368881.1\|3802989_3804006_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_043133898.1\|3804690_3805332_+	recombinase family protein	NA	NA	NA	NA
WP_171269803.1\|3805736_3806054_+	hypothetical protein	NA	NA	NA	NA
WP_010676219.1\|3806039_3807137_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_124245252.1\|3807871_3808141_-	hypothetical protein	NA	NA	NA	NA
WP_012564931.1\|3808417_3809365_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
3810435:3810453	attR	NA	NA	NA	NA

DBSCAN-SWA_13

4212084 : 4264260

Cafeteria_roenbergensis_virus(16.67%)

transposase,integrase

attL 4231660:4231675|attR 4268054:4268069

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_171268559.1\|4212084_4213182_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_171268949.1\|4213234_4214479_-	retention module-containing protein	NA	NA	NA	NA
WP_042649774.1\|4215218_4216661_+	ammonia-forming nitrite reductase cytochrome c552 subunit	NA	NA	NA	NA
WP_171268948.1\|4216712_4217366_+	cytochrome c nitrite reductase pentaheme subunit	NA	NA	NA	NA
WP_171269847.1\|4217362_4218040_+	cytochrome c nitrite reductase Fe-S protein	NA	NA	NA	NA
WP_042649770.1\|4218039_4218996_+	cytochrome c nitrite reductase subunit NrfD	NA	NA	NA	NA
WP_171268947.1\|4219145_4221107_+	heme lyase NrfEFG subunit NrfE	NA	NA	NA	NA
WP_042649769.1\|4221103_4221679_+	DsbE family thiol:disulfide interchange protein	NA	NA	NA	NA
WP_171268946.1\|4221675_4222860_+	heme lyase NrfEFG subunit NrfF	NA	NA	NA	NA
WP_042649768.1\|4222997_4223450_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_042649767.1\|4223803_4224724_+	serine hydrolase	NA	NA	NA	NA
WP_082030100.1\|4224893_4225037_+	DUF2256 domain-containing protein	NA	NA	NA	NA
WP_171268945.1\|4225036_4226557_+	cryptochrome/photolyase family protein	E3T4R9	Cafeteria_roenbergensis_virus	2.1e-47	31.8
WP_171268944.1\|4226710_4227964_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_042649765.1\|4228035_4228710_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_171268943.1\|4228877_4230809_+	amidohydrolase family protein	NA	NA	NA	NA
WP_042649763.1\|4230839_4231976_-	HPP family protein	NA	NA	NA	NA
4231660:4231675	attL	NA	NA	NA	NA
WP_171268941.1\|4233404_4235684_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_042649680.1\|4235845_4236781_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042649683.1\|4236860_4237610_-	siderophore ferric iron reductase	NA	NA	NA	NA
WP_171268940.1\|4237702_4239847_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_171268939.1\|4240115_4241027_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_043133101.1\|4241268_4242009_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_171268938.1\|4242071_4242974_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_042648128.1\|4243075_4243714_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_042648127.1\|4244111_4245140_+	isopenicillin N synthase family oxygenase	NA	NA	NA	NA
WP_042648126.1\|4245265_4246429_+	PLP-dependent transferase	NA	NA	NA	NA
WP_005326697.1\|4246529_4247387_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.3e-27	32.2
WP_109422568.1\|4248144_4249362_+	J domain-containing protein	NA	NA	NA	NA
WP_099993964.1\|4249865_4250882_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_171268937.1\|4251462_4252410_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.8e-41	35.7
WP_042649575.1\|4253066_4254017_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_171268936.1\|4259111_4260280_-\|transposase	IS3-like element ISAeme20 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.6e-69	46.4
WP_171268935.1\|4260506_4260653_-	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_171268934.1\|4260754_4261672_+	WYL domain-containing protein	NA	NA	NA	NA
WP_010674967.1\|4261735_4262017_-	hypothetical protein	NA	NA	NA	NA
WP_104453295.1\|4262141_4262894_-	HDOD domain-containing protein	NA	NA	NA	NA
WP_010674969.1\|4263015_4264260_-\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	4.9e-39	29.1
4268054:4268069	attR	NA	NA	NA	NA

DBSCAN-SWA_14

4535391 : 4667668

112

Planktothrix_phage(12.5%)

transposase,integrase,tRNA

attL 4597054:4597071|attR 4614080:4614097

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205051.1\|4535391_4536729_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_042648938.1\|4536860_4537622_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.6e-30	40.0
WP_042648939.1\|4537618_4538293_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_042648940.1\|4538330_4539104_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012564931.1\|4539150_4540098_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_042648941.1\|4540680_4541115_-	hypothetical protein	NA	NA	NA	NA
WP_042648942.1\|4541157_4542198_-	peptidase M35	NA	NA	NA	NA
WP_171268881.1\|4542519_4543158_-	DUF2913 family protein	NA	NA	NA	NA
WP_005328097.1\|4543239_4544535_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	9.3e-49	31.7
WP_042648944.1\|4544802_4545453_-	DedA family protein	NA	NA	NA	NA
WP_042648945.1\|4545800_4546766_+	hypothetical protein	NA	NA	NA	NA
WP_042648946.1\|4546807_4547701_+	NERD domain-containing protein	A0A2R2ZH57	Clostridioides_phage	1.3e-20	29.3
WP_171269463.1\|4547760_4548867_-	DUF1615 domain-containing protein	NA	NA	NA	NA
WP_005328087.1\|4549153_4550242_+	sterol desaturase family protein	NA	NA	NA	NA
WP_041205987.1\|4550299_4551958_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_005328082.1\|4552481_4555706_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_041205988.1\|4555722_4556859_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.6e-49	33.3
WP_171269850.1\|4557527_4558340_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_005328073.1\|4558661_4560008_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_005328071.1\|4560242_4560839_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_005328069.1\|4561010_4561664_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_042648947.1\|4561917_4563150_+	phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	3.1e-110	49.1
WP_171269462.1\|4563255_4563579_-	diacylglycerol kinase	NA	NA	NA	NA
WP_005328062.1\|4563776_4564841_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	1.7e-85	49.0
WP_005328061.1\|4565048_4565834_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	8.8e-10	27.8
WP_005328058.1\|4565820_4566828_-	vitamin B12 ABC transporter permease BtuC	NA	NA	NA	NA
WP_041205990.1\|4566913_4567645_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005328056.1\|4567757_4568114_+	DMT family protein	NA	NA	NA	NA
WP_171277307.1\|4568149_4569307_+	PilT/PilU family type 4a pilus ATPase	NA	NA	NA	NA
WP_041205992.1\|4569578_4570850_+	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_005328051.1\|4571009_4571252_-	FeoC-like transcriptional regulator	NA	NA	NA	NA
WP_005328050.1\|4571295_4573566_-	Fe(2+) transporter permease subunit FeoB	NA	NA	NA	NA
WP_005328049.1\|4573562_4573790_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_005328048.1\|4573910_4574240_+	translation initiation factor	NA	NA	NA	NA
WP_041205993.1\|4574484_4575042_+	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_041205994.1\|4575242_4576181_+	DUF2157 domain-containing protein	NA	NA	NA	NA
WP_005328044.1\|4576277_4577285_+	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_042648949.1\|4577391_4577889_+	GDYXXLXY domain-containing protein	NA	NA	NA	NA
WP_042648952.1\|4578083_4578836_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_081934473.1\|4579112_4579367_+	hypothetical protein	NA	NA	NA	NA
WP_041205253.1\|4579503_4580841_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_042648671.1\|4580913_4581201_-	hypothetical protein	NA	NA	NA	NA
WP_171269852.1\|4581713_4581938_-	hypothetical protein	NA	NA	NA	NA
WP_042649946.1\|4581934_4583884_-	hypothetical protein	NA	NA	NA	NA
WP_052833539.1\|4583911_4584316_-	hypothetical protein	NA	NA	NA	NA
WP_099368881.1\|4585137_4586154_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_042649750.1\|4586835_4588212_-\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	1.3e-45	25.6
WP_005330899.1\|4588402_4588900_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_005330897.1\|4588889_4589603_+	DUF4269 domain-containing protein	NA	NA	NA	NA
WP_005330895.1\|4589599_4590328_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_042649749.1\|4590448_4590697_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_042649748.1\|4590903_4591527_-	glutathione S-transferase	NA	NA	NA	NA
WP_158319064.1\|4591867_4592497_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_041206992.1\|4592587_4593727_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A077SLN2	Escherichia_phage	6.1e-145	68.2
WP_041205574.1\|4593784_4594210_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206994.1\|4595308_4596316_+	Fic family protein	D7RWK9	Brochothrix_phage	3.4e-06	24.2
WP_012564931.1\|4596876_4597824_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
4597054:4597071	attL	NA	NA	NA	NA
WP_042648291.1\|4598565_4599201_-	hypothetical protein	NA	NA	NA	NA
WP_088821966.1\|4599267_4600355_-\|transposase	IS3-like element ISAs22 family transposase	NA	NA	NA	NA
WP_025201450.1\|4600539_4600842_-	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_034523852.1\|4600834_4601191_-	hypothetical protein	NA	NA	NA	NA
WP_021139619.1\|4601338_4602544_-\|integrase	site-specific integrase	Q19US1	Mannheimia_phage	6.5e-12	34.6
WP_042648290.1\|4603386_4603941_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_042648289.1\|4604234_4606088_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_042648288.1\|4606200_4606845_-	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_005331986.1\|4607055_4607805_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_005331987.1\|4607801_4608002_-	Trm112 family protein	NA	NA	NA	NA
WP_005331989.1\|4608152_4609148_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_005331991.1\|4609147_4610917_-	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	4.2e-60	30.5
WP_042649661.1\|4611120_4613376_-	DNA internalization-related competence protein ComEC/Rec2	NA	NA	NA	NA
WP_042649660.1\|4613404_4613923_+	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_042649659.1\|4613916_4614411_+	DUF2062 domain-containing protein	NA	NA	NA	NA
4614080:4614097	attR	NA	NA	NA	NA
WP_042649658.1\|4614537_4616043_+	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	1.9e-85	46.6
WP_005329100.1\|4616199_4617390_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_042649657.1\|4617535_4618477_-	hypothetical protein	NA	NA	NA	NA
WP_042649656.1\|4618679_4619717_-	porin	NA	NA	NA	NA
WP_119196704.1\|4619988_4621257_-\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	2.3e-60	33.7
WP_119196703.1\|4621261_4624519_-	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_119196702.1\|4624519_4625797_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_119196699.1\|4625793_4627821_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_171269854.1\|4628223_4630296_+	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	7.9e-42	27.3
WP_171269855.1\|4630440_4631100_+	DUF2057 domain-containing protein	NA	NA	NA	NA
WP_171269856.1\|4631173_4632070_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	2.8e-12	24.2
WP_043128809.1\|4632228_4633377_-	MFS transporter	NA	NA	NA	NA
WP_042649651.1\|4633617_4634568_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_139751181.1\|4634894_4636286_+	alkaline phosphatase	NA	NA	NA	NA
WP_042649649.1\|4636309_4637677_+	alkaline phosphatase	NA	NA	NA	NA
WP_042649648.1\|4637727_4638411_+	hypothetical protein	NA	NA	NA	NA
WP_042649647.1\|4638455_4639229_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_041206035.1\|4639455_4639851_+	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_005329071.1\|4640067_4640658_+	transcriptional regulator UhpA	NA	NA	NA	NA
WP_005329069.1\|4640654_4642175_+	signal transduction histidine-protein kinase/phosphatase UhpB	NA	NA	NA	NA
WP_041206036.1\|4642196_4643531_+	MFS transporter	NA	NA	NA	NA
WP_021141234.1\|4644354_4645581_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|4645638_4646043_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_042649645.1\|4646946_4647735_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005330345.1\|4647832_4648792_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_041206038.1\|4648881_4649625_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-36	38.7
WP_041207009.1\|4649825_4650665_+	sterol desaturase family protein	NA	NA	NA	NA
WP_171269857.1\|4650727_4652128_-	amino acid permease	NA	NA	NA	NA
WP_041206039.1\|4652137_4653037_-	homocysteine S-methyltransferase family protein	NA	NA	NA	NA
WP_161507019.1\|4653311_4653854_-	hypothetical protein	NA	NA	NA	NA
WP_041206040.1\|4653874_4655194_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_025327511.1\|4655386_4656097_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_005328825.1\|4656187_4657006_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-22	32.1
WP_042649945.1\|4657112_4658762_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_041206042.1\|4658779_4661017_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_081805723.1\|4661221_4661761_-\|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA
WP_167332172.1\|4662368_4662509_+	hypothetical protein	NA	NA	NA	NA
WP_005325257.1\|4663212_4664820_+	malate synthase A	NA	NA	NA	NA
WP_005325258.1\|4664893_4666207_+	isocitrate lyase	NA	NA	NA	NA
WP_041205253.1\|4666330_4667668_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_CP038449

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038449_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038449_1

115302-115421

Orphan

Consensus_repeat	Method
GTAGCAAGAACTCCGCTCACCGGGGAGCGAGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038449_1

>merge|NZ_CP038449|1|115302-115421|CRISPRCasFinder
GTAGCAAGAACTCCGCTCACCGGGGAGCGAGGTGTTCTGATTGGTTCGGCGTCCGGCGGTGGCCGGTACCTGCGGCAGGGCCTGGAGTAGCAAGAACTCCGCTCACCGGGGAGCGAGGTG

>NZ_CP038449|1|1|115302-115421|CRISPRCasFinder
GTAGCAAGAACTCCGCTCACCGGGGAGCGAGGTG	TTCTGATTGGTTCGGCGTCCGGCGGTGGCCGGTACCTGCGGCAGGGCCTGGA
GTAGCAAGAACTCCGCTCACCGGGGAGCGAGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038449.1\|WP_171270127.1\|111816_112005_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270128.1\|111084_111471_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270122.1\|120212_120971_-\|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|239318
NZ_CP038449.1\|WP_171270117.1\|125234_126614_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319756
NZ_CP038449.1\|WP_171270126.1\|112019_112364_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270118.1\|124771_125224_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270125.1\|112377_112569_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270130.1\|102251_102446_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270124.1\|116937_119541_-\|TraC-family-protein	unknown	unknown	gnl\|CDD\|274279
NZ_CP038449.1\|WP_171270119.1\|124014_124701_-\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381603
NZ_CP038449.1\|WP_119196703.1\|105895_109153_+\|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl\|CDD\|223683
NZ_CP038449.1\|WP_119196702.1\|104617_105895_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341169
NZ_CP038449.1\|WP_171270116.1\|126625_127786_-\|type-F-conjugative-transfer-system-secretin-TraK	unknown	unknown	gnl\|CDD\|368991
NZ_CP038449.1\|WP_119196704.1\|109157_110426_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NZ_CP038449.1\|WP_171270123.1\|119573_120203_-\|TraV-family-lipoprotein	unknown	unknown	gnl\|CDD\|370611
NZ_CP038449.1\|WP_119196699.1\|102593_104621_+\|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|223363
NZ_CP038449.1\|WP_171270131.1\|101927_102233_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270115.1\|127785_128628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377500
NZ_CP038449.1\|WP_171270120.1\|123025_123619_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270121.1\|121001_122909_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP038449.1\|WP_119196703.1\|105895_109153_+\|type-I-restriction-endonuclease-subunit-R	gnl\|CDD\|223683	COG0610, COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	3.00969e-78
NZ_CP038449.1\|WP_119196702.1\|104617_105895_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341169	cd17280, RMtype1_S_MspEN3ORF6650P_TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Marinobacter species EN3 S subunit (S.MspEN3ORF6650P) TRD1-CR1, Methanothermobacter marburgensis str. Marburg S subunit (S.Mma2133ORF14720P) TRD2-CR2 and Nostoc species NIES-3756 S subunit (S.Nsp3756ORF27100P) TRD1-CR1. The recognition sequences of Marinobacter species EN3 S subunit (S.MspEN3ORF6650P), Methanothermobacter marburgensis str. Marburg S subunit (S.Mma2133ORF14720P), and Nostoc species NIES-3756 S subunit (S.Nsp3756ORF27100P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	4.72969e-17
NZ_CP038449.1\|WP_171270122.1\|120212_120971_-\|thioredoxin-fold-domain-containing-protein	gnl\|CDD\|239318	cd03020, DsbA_DsbC_DsbG, DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds formed by DsbA and prevent aggregation of incorrectly folded proteins. DsbC and DsbG are kept in their reduced state by the cytoplasmic membrane protein DsbD, which utilizes the TRX/TRX reductase system in the cytosol as a source of reducing equivalents. DsbG differ from DsbC in that it has a more limited substrate specificity, and it may preferentially act later in the folding process to catalyze disulfide rearrangements in folded or partially folded proteins. Also included in the alignment is the predicted protein TrbB, whose gene was sequenced from the enterohemorrhagic E. coli type IV pilus gene cluster, which is required for efficient plasmid transfer.	2.71303e-16
NZ_CP038449.1\|WP_171270117.1\|125234_126614_-\|hypothetical-protein	gnl\|CDD\|319756	cd16430, TraB, TraB is a homolog of VirB10 which forms part of core complex in Type IV secretion system (T4SS). This family contains TraB (VirB10 homolog) and a component of the type IV secretion system (T4SS), and similar proteins. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TraB is localized similarly to related proteins in other systems, but unlike in other systems, Neisseria gonorrhoeae TraB does not require the presence of other T4SS components for proper localization. It has been shown to be expressed with TraK (VirB9 homolog) at low levels in wild-type cells, suggesting that gonococcal T4SS may be present in single copy per cell and the small amounts of these proteins are sufficient for DNA secretion.	2.83396e-79
NZ_CP038449.1\|WP_171270123.1\|119573_120203_-\|TraV-family-lipoprotein	gnl\|CDD\|370611	pfam09676, TraV, Type IV conjugative transfer system lipoprotein (TraV). This entry includes TraV, which is a component of conjugative type IV secretion system. TraV is an outer membrane lipoprotein that is believed to interact with the secretin TraK. The alignment contains three conserved cysteines in the N-terminal half.	7.14861e-18
NZ_CP038449.1\|WP_171270116.1\|126625_127786_-\|type-F-conjugative-transfer-system-secretin-TraK	gnl\|CDD\|368991	pfam06586, TraK, TraK protein. This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.	1.1124e-05
NZ_CP038449.1\|WP_119196704.1\|109157_110426_+\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.38697e-70
NZ_CP038449.1\|WP_119196699.1\|102593_104621_+\|SAM-dependent-DNA-methyltransferase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	3.21849e-62
NZ_CP038449.1\|WP_171270124.1\|116937_119541_-\|TraC-family-protein	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	2.91317e-120
NZ_CP038449.1\|WP_171270115.1\|127785_128628_-\|hypothetical-protein	gnl\|CDD\|377500	pfam05309, TraE, TraE protein. This family consists of several bacterial sex pilus assembly and synthesis proteins (TraE). Conjugal transfer of plasmids from donor to recipient cells is a complex process in which a cell-to-cell contact plays a key role. Many genes encoded by self-transmissible plasmids are required for various processes of conjugation, including pilus formation, stabilisation of mating pairs, conjugative DNA metabolism, surface exclusion and regulation of transfer gene expression. The exact function of the TraE protein is unknown.	1.46314e-14
NZ_CP038449.1\|WP_171270119.1\|124014_124701_-\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381603	cd13400, LT_IagB-like, Escherichia coli invasion protein IagB and similar proteins. Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.	8.25198e-41

>NZ_CP038449.1|WP_171270125.1|112377_112569_+|hypothetical-protein
MAKYRYGLFQSPAKTDPSVDDLQMAEDMAREMSRSLNGEPVAVWGENDETLTLFAGFEQFKPV
>NZ_CP038449.1|WP_171270126.1|112019_112364_+|hypothetical-protein
MIYYLALSLISTIAVIWLFNYWMAEFRNIIQRDQTLQFAISAVILSGISLVTIIKPFPLVAKFFDDLVLGSPQEIRILVFPLMVFLLTGAYGGLLAGIVCMWRKLPTLLGSRQS
>NZ_CP038449.1|WP_171270127.1|111816_112005_+|hypothetical-protein
MQVQLKVAYTLQIVGFILLVISAGFEWPILWPTFGFFMLAKGTWDVVNHLISKRPRVNNYNR
>NZ_CP038449.1|WP_171270128.1|111084_111471_+|hypothetical-protein
MVKEDWLYLVERLEFVGEGLCLEAALIVREVLDIDIDAMEDPKLEYAACSDVGHLISTAIDREDFDTEHLPNVRSLEAEMTGRILNYRLHRGWLTKAQGSPIDFPSLAEIIGKNGHEARCYPGSTRKY
>NZ_CP038449.1|WP_119196704.1|109157_110426_+|ISL3-family-transposase
MLDLLNLPGIKPVDMRHEGKCLVIVAEPVTVDVPLCGDCNTPMHRHGTRKNKFMDTPLYMEPVRLEVQRPRFRCESCGKMSMPELSFLDDKRRATKRLVDVIRQQCLGTTFHALAEQTGVAVNTVKNIAHDLIEELSQTVRYETPVIMGIDEVNLAGGYRCVITNLATNNVFDMLEHRTQEHLKPFFKDLPDADKVEWVCTDMWRPFKRSFAQHLPNAKLVIDKFHVVKMASEALEAERKNYQAQLSKEDRIYVKKSIRWLTLKRPGNLTPAEQKALEVVKQAIPELAVAYDFKEAFFCIYDEPDKQSAQNAFEAWENSLPPYGMEPFKKLVKTVHNHYDDIFAYWDAPFSITNGYTEGLNGLIKMSNRLGRGYSYPIIRAKTLYSKEARKVGSGIRAGHGKVEYGPHIPTLLKQAESGELD
>NZ_CP038449.1|WP_119196703.1|105895_109153_+|type-I-restriction-endonuclease-subunit-R
MQSAAHQEKHFQQYIIDRLVEQGWKLGDSKFYDTERAVYPEDLESWIKSSGQQGKWEKLERLNGTKTLEVLMDRLDKALEKQGTMQVLRQGFSIAGCGLIEMTEAAPEDRRNEAVIKRYQANILRVVPELKYHPAREFAIDLVLFINGLPVATVELKTDFTQSAEAAMDQYRNDRLPYDPKTKRREPLLTFKRGAVVHFAMSDSEIMMATKLDGENTFFLPFNKGRKDESGAVHAGNPPGEIKADGTQEYPVAYFWEAVCQPDSWLRIFHSFVYVEKKDVVDIQGNWSKKETLIFPRFHQWTAVNQMLTDARENGAGMTYLCDHSAGSGKTSTISWTAHDLVKLREDNGDSVFNSVIIVTDRNVLDGQLQDAVKQIDHQFGVIAAIDRQKSSKSKSKQLSEALLSGTPIVVVTIQTFPYAMEAIITDKALKGKNFAVIIDEAHNSQTGSTAAKLQAALGMSGQGKMSTMTVDELLEQLQKSRARPDNISYFAFTGTPKHSTLMLFGRPTDPSQPASNDNPPQAFHLYTMRQAIEEKFILDVLKGYVPYKTAFNLSKQLEDSKRVSGKAAKRALAQWMSLHPTNVTQKVQFIVEHFTKNVAHRLDGKAKAMVVTSSRAAAIRYKKAFDRYIEQHSEYGFIHSLVAFSGKMTGKQVMHQDDSEFKDDVFIVDENEEFTEQSMNPDVQGQDLRFAFDRPEYRVMLVADKFQTGFDQPKLVAMYVDKKIANHVEIVQTFSRLNRTAPGKDEVFIIDFVNDPENVRQAFTTYNKGAHIDEVQDLNVVYEIKERLDEHGLYDDKDLAAFKEARFKTIRDITHTKSPQHKALYAATAGATALYNDKMKMLRDGMATWEAAFEKARAKGDEAGMKSADHHQDEYAEQIKALIGFKSDLGRFCRTYSYIAQLIDFGDPELENFAAFAKLLQKRLLHEAPETVDLTGLVLTGFDINARSDNAEDEGETPVLQPIGAGGGGVAGDKPKFVKEIIERLNSLFGEATPIQDQVAFVNQISAITGESDVVMAQVESNTREQAMKGNLPGAVQQAVVRALSSHQKLATQVLKSDRQGMTALVDMVYDLLREGKDIDLDMD
>NZ_CP038449.1|WP_119196702.1|104617_105895_+|restriction-endonuclease-subunit-S
MSQYRAYPAYKDSGIEWIGQVPEHWKVARVKRLASLRNERRNDVSTDTIYIGLEDVEAGSGQYKPTNGSSRQSEDSTVGIFYEGDVLYGKLRPYLRKAIISEMAGCCSTEFLVLRAEKTEPRWLQEWLLTPDVTHQIESGCEGAKMPRADWGHIGSIEVVYPDQPEQAKILTTLDRETARIDALVEKKNRFIELLKEKRQALITHAVTKGLDPNVKMKDSGVEWIGLVPEHWDVKPFFALVTELNRKNVGLVETNILSLSYGNIIQKPETRNMGLTPESYETYQIVESGETVFRFTDLQNDKHSLRSALVTQRGIITSAYMAVKPHSIDSTYFAWLMRSYDLCKVFYAMGGGLRQSLKFEDVRRLPVLIPPVDEQSAITNTINAGTARIDALVEKTEQSITLLKERRAAFITAAVTGQIDLRGKQ
>NZ_CP038449.1|WP_119196699.1|102593_104621_+|SAM-dependent-DNA-methyltransferase
MNDFTGSAASQADFIWKNAEDLWGDFKHTDFGKIILPFTLLRRLECALESTREAVREAHTAFKDADIELDTILRSTANYPFYNISEYSLATLGSTKTRRNLEDYIALFSDNARAIFEEFEFGNTVIRLEKAGLLYKICQNFAKIDLHPDVVPDRVMSNIYEHLIRRFGAEVNEGAEDFMTPRDIVHLATALLLDPDDALFEASPGLIRTLYDPTCGTGGFLTDAMNHVGDYGNRDKIPPVLVPHGQELEPETHAVCVAGMLIRRLESDPGRDLSKNIRQGSTLSNDQFAGERFHYCLSNPPFGKKWEKDKTAVEAEHKKGELGRFGPGLPKISDGSMLFLMHLASKLELPINGGGRAAIVLSGSPLFNGGAASGESEIRRWLLEDDLIEAIVALPTDLFFRTNIATYLWILSNKKPQERKGKVQLINATDLWTSIRNEGNKRRIVSDEQRRQILDIYAAGETGALSRMLDYRTFGYRRIRVLRPLRMTLELDKVGMERLEAEAAWEKLSDAHQTFWREALKPLIGQTQPYSWAETFVSNSIKSDEAKQLKVKSNKTLITALINAFGHKDPKAEPVTDSNGELVPDTDLTDYENVPYLEDIDDYFAREVLPHVPDAWLDESFTDARDGQLGRVGYEINFNRFFYQYQPPRKLHDIDEDLNQVEAEIAALLAEVASE
>NZ_CP038449.1|WP_171270130.1|102251_102446_+|hypothetical-protein
MALSEERRAARVFMLRHAAAWLLDLESTELAEGADGRPDQVKVKEALAVSKRLEAMADRLESKR
>NZ_CP038449.1|WP_171270131.1|101927_102233_+|hypothetical-protein
MFNDEEWAWPDADEAYWALMPAETSGDPSPADCLVQELLEARVNIKLEGYGSRNDSDYCNGYLAGRFQSIDLSLRIVLRRLDVSPRQRYIAEHVLGQTATP
>NZ_CP038449.1|WP_171270124.1|116937_119541_-|TraC-family-protein
MFSTLQQRKRELVSHQKFGELIPVLDYYPEEQVFLLDPATLSFMIICQPLNGVSVEMSNLMRSIFTYEYPDDTTMVISTVGARDMIRVNNNWDALRSGRMEPKDWEFESLLNSLSKDYLVSACQEGLRPGMSTLNARNFEVWYSVTIPISNQVPTDDEMARVVEIKSDLVQKLRSMGGAPFVANHEQWLRRMQVLMNPGQNTAWAQGKTHVKPSIPLRHQILQPGRMVSLDRDGIVLAGDPKRPDENRSVRVLNCYRRPDYASLGDMYGFYSDWANGMGGIHNDFMLSLNIHFPNRKKAKNAFDARKILVTNQESAGVMRYSDRLRFQFEDIKAINHELEQENHAIINCWVQLSLFLDKNGREDADEKAVISYLDKIGYGYAVDRQIAMPLLLETLPLCHGYDPQIRSMLQRQEMFTTKYLETVAPVFGPWKGNSQNPVIVGYSREGQIITIDPFKTNASFNMAIAARSGAGKSVFAGNLVKQLLTTGEPGAVGSQDGGQVFVIDSGGSYKSLAGQFQSSQYIEFSEQQMFSLDPFVDLSGLLDEEDEALSDDPSGNTRYVTLAGGLKLTMITNQIKLMAAPDGKIDNFQSAAISRILLDMCVSSPEDASITFFAERCLAEEDQRIRDIGAQLHDFTRHGKYARLFDRRLAPTIQFDSRLIVCELGQLKAQPHLQTVVLMSVIQQAQDAMFQKDDGRRRAFILDEAWEYIGEGSATSNNAFFAEFIEAGWRRFRKTQAMGVCITQQVSDYYSSKTGKAIFANSPWLCTLAQEGPVISRLKTDKLMDAPQFVFNLMESVRTDKGQFSEVLIQYEGIYQVMRLYVDDRSMTIHTTDPEEKKIIAKYTSMGMSLRDAVIHATDDIKRMRR
>NZ_CP038449.1|WP_171270123.1|119573_120203_-|TraV-family-lipoprotein
MKKSTLALCAPLLLQLAGCSIVGQSESSCPGKPNGYVCKGPREVYEITNSKTSLFDGTQDGLDGDDSGKKGDAAGNKADASGAVIDLPAAGVIPSNSYSIYQDNLAAPEPLAVRADARVLRVLFAAYEDDSQSLNMPGYAYVEVEPKRWLVGAAANKQPAKIIPLQARQDADANLTHKQKVSSTVDPLGVKKITNTPGQIAIPAELLHK
>NZ_CP038449.1|WP_171270122.1|120212_120971_-|thioredoxin-fold-domain-containing-protein
MMKRSALLTLPLLVSILAHAEGLPMPQEEKELAVTKNLVKSAPIPLDGLVAAKDKNGNDIIVSTNGRYFLKGYLQDVYTNKTIRTIKDAQDAQYLTLSNMGLNLVDIGTIPYGNPQLPLQGRIMVDPYCPECTKLLKQLEPLRDKVHVEIMITPVAGKQSVITALNLWCTYEVNYDKGREVIDLLMKGAPYPNQPDQKQCKGQRVLLNTMLTRTFNLRALPAIWRVDGLAQAGIPTDLLAFLNERRPTEDQK
>NZ_CP038449.1|WP_171270121.1|121001_122909_-|hypothetical-protein
MGVNLAFICAPKSLEYPKSFLLPSRAQRLKDSGEVQMSMDKNTKAKTKQRSAKDAQSSTVITWHHFSAMRMFLATMEPTKTLSQEAIANLLGCTTTNTYSKWERGDQIPPSIVCRAMELLLYYSLVKAGRFKSEKAAQEEFFRFKEISAQSSAGLFTRAVDVDRKIRNIQLAAYDCMCMMGGHASNFTVATDGYDCNIVANKIIISPGWNRNGKLAGNALEVISNVAGLVAHDYTSMITYQNDGTGIPQYLINEYREKGIHYDGVIQTKYFGVKRVKDSMHITFTPEMAARFNKFLAEAAEIVKAEEAVIPSEAEMRESLRTIVKKMPEAVTSEAGIVSLPNLNFTINHCIGSNLRPKTRDINVIEKALCHLLDVDPESITYPAAMVLRNAYGKRTTDKSNINTHFFKAAIEGRTLHVQLRRPNALSALNELLSGVVANEESKRDIDREVALIRGRIGKITNGVVLLDDNYHQIVSPTIEISDILSRKGVIRVHLINAMERLLISCLGVDLSHTNMSYSVIRRASNQQHLFRSEAFNKYLTRRVAAEDQAKQEGWPQERLAAEIEQVKSDLKLLSGDEPTVQADCHFFKFDLTGDKALLTFKEQRFIDEINNALASYSPTVTPITDDDEDEEPSE
>NZ_CP038449.1|WP_171270120.1|123025_123619_-|hypothetical-protein
MSSKQMAPQRLPQQAHQDGYLGTKDSRYGKYHEFYSFKVHGSKAALNFVPDETRKQFLTVSLEAAELLNSSTRTYNWKNKSRVQLTRGEFLEVVAVLLGIGADCQCKFDNHGTPGGAKKGFQMIHQGNKVFVSVFEANKPPKSVPIPLMEATQVAHMMLSIYVDNYPGLTTDTVLTSLILATRKRDSTAGSVANGRT
>NZ_CP038449.1|WP_171270119.1|124014_124701_-|lytic-transglycosylase-domain-containing-protein
MMRIAKLVAIPLLVSTWAHSSVATTPYPVPEQKLTECVSTASATYGVPELVIRAILKQEAGLVGTMSQNSNGSYDLGPMQINTINLGLISKKYPFLDWRHITYNPCINIMVGTWFLQQKIQNRGGVIWEGVGDYHSTTPSKRSVYLRSFLAHYNQLKKQYGLKPLRRPAKLAVEEAIAGTQPSTALRLTPTSAIPPLMLSRDLPPRYMPKNPSLVSLFAMGALQHEPK
>NZ_CP038449.1|WP_171270118.1|124771_125224_-|hypothetical-protein
MNEQDKPLPPFNASGGPLTDDASQHTQGDVTSPPLTPDVPQDVTSGPINWLALLSVATILNFFVLVFVLYRLGTLSYYDIKDAPMIYYAQADEIVAHAMMQNDPAKAQNELIEQLKDTHGLVLSDESVLIASPEFKLFPTKTIDSESGKK
>NZ_CP038449.1|WP_171270117.1|125234_126614_-|hypothetical-protein
MSKLQEFTKKKSVRIGAAAVTLIGIAAIAQSGLDFNQETPRAKKVKQNLVQSNVFDTAAMEKIDTDTAQATYEQMKKDMHERSKQEQQLRDSQNRELNKVMTQLTKMQEQLATQNQIISVLSKNNQVVSGAVNDPRITRARQSGVTGENGVTTPAGTAQGPYSTLTPQQYQNVSRASGPVTNGMIRTVSQNKITNIKKTGQVEETPIEVVYVESRNGGKNAGKAQAQPKKPTNPEIEKKKRDMVKAKAKTYIPAGSIISGVMLNGVDAPTALSKNASPLPTTIRVKLDVLMPNSYNADLADCFVIGSVTGDLASERAYIRSVTMSCINERGESLETGMIGYAVSDYDGRNGIRGTVVSRAGKALIATFGASFLSAVAEASKPTAIPSLDQNPGDTTAFQTPNMGDVGKSGIMGGVAGGSDRLAQYAIAIADQQWPVIEISPGTPVTFFLEKGMSLPVVE
>NZ_CP038449.1|WP_171270116.1|126625_127786_-|type-F-conjugative-transfer-system-secretin-TraK
MRITTLSLTISLLLAPAAFAEGQLPVEVVNPEKLAEHNPVGQVGGIIANSMVPGAGAPLPVNMPEEQQLLLKMQKEAEANMPAGQFVDTGNLNDQLAEKVKSKYAPTQDLTVRPSGNVMVPVSLGLMNRIETNFHNVSVKTSDESAVLEVDGGVLYVTLNKREPVGLILMEAGVPASAINITAVPLDVPPALVRVRIPMSGAMMQDAFEYQRKAKDAEMVEKAMTEEDEIVRSDRHTERIKEILKYTALGQVPAGFTLADNLDEVPNAYRKPCNFENLANVLGQRMVGAREFVDVVLVTNKSTMDAVIKEEFCMSRDTLAVGVMDAASLRPGASTEVYVVRDKNWAKKQSQLQTRPRLDNNGSFGLNGYQRVAGSAPTAPSKSGLK
>NZ_CP038449.1|WP_171270115.1|127785_128628_-|hypothetical-protein
MADPIGNFFKALFSKDVPTRSRDRTDDVPLSGVPAADSESESKWAPLKPTLDGDDRQHSALSSWSAAMVKSNFMVISNVGLVAVVLLLVFNQMDKKPTIIVKPPVMTGEFRIEDGLPNKEWQQSWALFIAHMLGNVNPRNVEFVARQVTSLLSPNLQTAVDIDLRKVVEMMRMSGLSQTFEVQDLRYDANTGMVWCWGNKTTQLIGAKSSNNAGNETSDRRRWTYEFIIRLNEMGMPVVTHIDQYEGTPRYDRASEVTEEGQVLNPPKKNKGQHASKEPN

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Crispr_ID: NZ_CP038449_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038449_2

169352-169807

TypeIV-A

Consensus_repeat	Method
GTCTCTCCCGTGCGCGGGAGGGTTAACG	PILER-CR
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CRISPRCasFinder
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CRT

7 spacers

csf2gr7,DinG

The CRISPR arrays of NZ_CP038449_2

>merge|NZ_CP038449|2|169352-169807|PILER-CR,CRISPRCasFinder,CRT
GTCTCTCCCGTGCGCGGGAGGGTTAACGCATCAGGGCATGTCCGGCCCCGCGTTTTCCCGTGTCTCTCCCGTGCGCGGGAGGGTTAACGTAACGGATGATTTTCCGCAGTTGGCGTAGAACCGTCTCTCCCGTGCGCGGGAGGGTTAACGATCTGCTGTTTGATCCATTTTTTGACTCCTGTAAGTCTCTCCCGTGCGCGGGAGGGTTAACGGGATACGCCGGAGCTGATGGCCGGGCTGTAGATGTCCCTCCCGTGCGCGGGAAGGTTAACGGGCTAATGCTCAATGGAAGTTTTTCTTGGAATCGTCTCTCCCGTGCGCGGGAGGGTTAACGGGGCTCCGAGGCCCGCGAGGAGCAAAAGCGTCTGTCTCTCCCGTGCGCGGGAGGGTTAACGCGCCTGGCTATGCAGGCCAGCAAGCTGGCCGCCGTCCCTCCCGTGCGCGGGAGGGTATTGG

>NZ_CP038449|2|1|169352-169746|PILER-CR
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CATCAGGGCATGTCCGGCCCCGCGTTTTCCCGT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	TAACGGATGATTTTCCGCAGTTGGCGTAGAACC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	ATCTGCTGTTTGATCCATTTTTTGACTCCTGTAA
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGATACGCCGGAGCTGATGGCCGGGCTGTAGAT
GTCCCTCCCGTGCGCGGGAAGGTTAACG	GGCTAATGCTCAATGGAAGTTTTTCTTGGAATC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGGCTCCGAGGCCCGCGAGGAGCAAAAGCGTCT
GTCTCTCCCGTGCGCGGGAGGGTTAACG

>NZ_CP038449|2|2|169352-169807|CRISPRCasFinder
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CATCAGGGCATGTCCGGCCCCGCGTTTTCCCGT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	TAACGGATGATTTTCCGCAGTTGGCGTAGAACC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	ATCTGCTGTTTGATCCATTTTTTGACTCCTGTAA
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGATACGCCGGAGCTGATGGCCGGGCTGTAGAT
GTCCCTCCCGTGCGCGGGAAGGTTAACG	GGCTAATGCTCAATGGAAGTTTTTCTTGGAATC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGGCTCCGAGGCCCGCGAGGAGCAAAAGCGTCT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CGCCTGGCTATGCAGGCCAGCAAGCTGGCCGCC
GTCCCTCCCGTGCGCGGGAGGGTATTGG

>NZ_CP038449|2|1|169352-169807|CRT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CATCAGGGCATGTCCGGCCCCGCGTTTTCCCGT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	TAACGGATGATTTTCCGCAGTTGGCGTAGAACC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	ATCTGCTGTTTGATCCATTTTTTGACTCCTGTAA
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGATACGCCGGAGCTGATGGCCGGGCTGTAGAT
GTCCCTCCCGTGCGCGGGAAGGTTAACG	GGCTAATGCTCAATGGAAGTTTTTCTTGGAATC
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGGCTCCGAGGCCCGCGAGGAGCAAAAGCGTCT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	CGCCTGGCTATGCAGGCCAGCAAGCTGGCCGCC
GTCCCTCCCGTGCGCGGGAGGGTATTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038449.1\|WP_171270095.1\|163071_164187_+\|TraU-family-protein	unknown	unknown	gnl\|CDD\|377717
NZ_CP038449.1\|WP_171270092.1\|168313_168556_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270099.1\|155114_155378_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270096.1\|161645_162950_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274276
NZ_CP038449.1\|WP_171270084.1\|178063_178303_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270085.1\|177784_178054_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|367788
NZ_CP038449.1\|WP_171270097.1\|161179_161686_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_CP038449.1\|WP_171270011.1\|173699_174275_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270093.1\|167414_168230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270086.1\|175699_176242_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270090.1\|171043_171748_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270089.1\|171747_173700_-\|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NZ_CP038449.1\|WP_171270091.1\|168885_169230_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270088.1\|174271_175069_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270176.1\|177104_177539_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP038449.1\|WP_171270087.1\|175208_175517_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270098.1\|155352_156009_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270094.1\|164188_167338_+\|conjugal-transfer-protein-TraN	unknown	unknown	gnl\|CDD\|184877
NZ_CP038449.1\|WP_171270177.1\|170002_170851_-\|CRISPR-associated-protein-Csf2	csf2gr7	mkCas0162_csf2gr7_CAS-IV-A	gnl\|CDD\|274435
NZ_CP038449.1\|WP_171270100.1\|154100_154661_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP038449.1\|WP_171270089.1\|171747_173700_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	1.33351e-32
NZ_CP038449.1\|WP_171270095.1\|163071_164187_+\|TraU-family-protein	gnl\|CDD\|377717	pfam06834, TraU, TraU protein. This family consists of several bacterial TraU proteins. TraU appears to be more essential to conjugal DNA transfer than to assembly of pilus filaments.	6.71362e-83
NZ_CP038449.1\|WP_171270176.1\|177104_177539_+\|hypothetical-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	2.75435e-08
NZ_CP038449.1\|WP_171270096.1\|161645_162950_+\|hypothetical-protein	gnl\|CDD\|274276	TIGR02743, hypothetical_protein, type-F conjugative transfer system protein TraW. This protein is an essential component of the F-type conjugative transfer sytem for plasmid DNA transfer and has been shown to be localized to the periplasm.	2.43106e-16
NZ_CP038449.1\|WP_171270085.1\|177784_178054_+\|radical-SAM-protein	gnl\|CDD\|367788	pfam04055, Radical_SAM, Radical SAM superfamily. Radical SAM proteins catalyze diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation.	0.000561189
NZ_CP038449.1\|WP_171270097.1\|161179_161686_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.88076e-13
NZ_CP038449.1\|WP_171270094.1\|164188_167338_+\|conjugal-transfer-protein-TraN	gnl\|CDD\|184877	PRK14877, PRK14877, conjugal transfer mating pair stabilization protein TraN; Provisional.	0
NZ_CP038449.1\|WP_171270177.1\|170002_170851_-\|CRISPR-associated-protein-Csf2	gnl\|CDD\|274435	TIGR03115, cas7_csf2, CRISPR type IV/AFERR-associated protein Csf2. Members of this family show up near CRISPR repeats in Acidithiobacillus ferrooxidans ATCC 23270, Azoarcus sp. EbN1, and Rhodoferax ferrireducens DSM 15236. In the latter two species, the CRISPR/cas locus is found on a plasmid. This family is one of several characteristic of a type of CRISPR-associated (cas) gene cluster we designate Aferr after A. ferrooxidans, where it is both chromosomal and the only type of cas gene cluster found. The gene is designated csf2 (CRISPR/cas Subtype as in A. ferrooxidans protein 2), as it lies second closest to the repeats.	0.00141486

>NZ_CP038449.1|WP_171270091.1|168885_169230_+|hypothetical-protein
MSKQEPLTIEVAAERLSGIVSADYKWPELLPGWQLEFIAYPEGDLDMDMLHPVARVFWSDDNEPLPLPYKSDESPITVWDLIAVKLPYMTTFGYATVVDKPKDSHLSLVPGEQV
>NZ_CP038449.1|WP_171270092.1|168313_168556_+|hypothetical-protein
MIALKIATVHIAERVECSFHSAIKSGTPVYRAFNLTHSDAKAHKHANLLMLNGLDVPVSFCEGEIDQSQLQQFRYRSICN
>NZ_CP038449.1|WP_171270093.1|167414_168230_+|hypothetical-protein
MKVKLIATTVLAMTALAGCSSTPKDMGQPFSQDKSKSVALNVAAYAGYPHVLRDNTYDKGLDTLVTSTSNALLLANDLSGSLGSLGGGALGMGLGFISGMADQYPLDAGKVFTAKLQPGENYKSAATVLRVLQANYQKRDVDSADGDKLRSLLAKPSLADYVCEPTTVKDYDFSCYDPADDRYNTYVKATRPANGLEFAEVMPLTQGSYGVFFIRNDRGSVLTPKKDATDAYFYLKDGSYVLGNSNTILPRVAPREDGKRLVFIDGKAVLI
>NZ_CP038449.1|WP_171270094.1|164188_167338_+|conjugal-transfer-protein-TraN
MQQDGGPYGSTMKHTSLSVLFTYFIVFVFHPAFMAVGLAAMMSPGRALAAQSDELYQNLKSKYQLDTPDNDVSKENEVLDIKQKYGKGSGGAEEVIKSLQKYQGQDHTGAKVDMGKYQGGNFSSGYQSTYNDAAAGGVGINSLSMPGVSGHNVSVKYAPQGGVKLARDANGNITNTQVGGVKTNDVSSVVGAEASNAETSFGAKNTYNPHNEEDLIREVKSTVSKAQTGGNTSDSVAYRTIMESYRSNKPQNISRDDPVFLGAKNAVDDARLQKGLFEGSCKSLTTTTTKETHYPDWREHRCSAPKKDNYQSCELKRDLNVPVYIEGGDGQMSICGPNCVKIRIGKAGDNYWNGNACGIFQNALDLRFAAAAKVKTALVTLAEWDDHMEVKMGDQTIFYHVDGEMRDASYPFRQAGVDCETNTSWYTGDGTGTKRVGGYFDVTNLVESALSKGGEQVIRMSNRVAVGDGGEGHFEITLYFEDMGFKDDHIQIPAGCYDAVLKSDGTCKMDKWQPIDVGTKRLPSTILDLGKPLFPGDTGYLTWRANAEGYFCDPLAQSKLVVGDKSYSYDDIKNMPDGCAAEKANPMCVEKSRDCVPGWDDAGTGQCYMEEIVYECDEGKTVSEIVSNTTNTCGELPCIGTDCSAGAPEVNQDFAQAAGLLQAMSFLSADGNCTAADPSQCKVFPGEQKYCGWAVGVVGSLADTNCCEAPQGGPDMLSAAMSAFSIIRSVNWQSVAASASEVTGSTSFNAIYNGVSEFGTTIGNATASAIQAAGEAMTSATNTVMSSLGQEVAYEGAKVAGSEAAELTMDGLIQAAEQKVMGTVYDTLGEKLVGSLIQKEGSTFVLTEMGANIVMALNVVMIAYTVYKVTMMIAQMLAACKPEEMETASKIHEKACFKVGGEYCLKEINVGVKKVCVKRAQNYCCYSSMLPRIVMQQAVIQLGLEDCSGITVAQLQKLDWSKIDLTEWVAEATLGGALPDGQDDLTLEALTGTGHVLAGGEDRDNTLERLNNRYSDDKLIKASSETQDLIQLESVDCSYLPRPAICKFQ
>NZ_CP038449.1|WP_171270095.1|163071_164187_+|TraU-family-protein
MRAPRWLLAGVFALTSIPSLAAEAGKDFNLDCEDGKILTGIIDKICWSCVLPMRIMGVGPKPAGAAKDKPVCMCTDSNGVPEIGWQLGYYQPARIEEVVKTPWCSPFLGGIKLQDSSFEVGRERASDLADKPQNVFMDSHYFSYPVFQLLNLLMIPACAGDNHQDIDLLTMSEIDPLWSNDLLTFVLNPESVVFANPLALAWCMADCVATTANVESEKNYFCAGCDGLIYPHTGNIHGIKDPVQNSSLLVQRQLAALHRRGLAEKTMGEDEMCGSTYSYFVPRSQYKVSMLYPVPESSNKRPLFTPPKQGNGSGTTMPSNFILNENCCHRLGESVHQWSTMKGGRSRPGKENYVYMIWRYVDCCVTYKGGV
>NZ_CP038449.1|WP_171270096.1|161645_162950_+|hypothetical-protein
MKKTLLVGLLLSGNCFAAQGDTASESVVDIDSIAREMAIKAKAIQQQALKDPSMTAVLKESEQITDEQREKAQALTADAMKKAASPQTTQQMSAVFGSMKQSDLVAVLGADKSTNTDKPEAAAMGNGMMFLSLSMSDKDLMASLEVAAKYSMPVSFIGLLKGTTTITDTAMQLRKLARKAGVSEDREPQVLLNPVGFEKYGVNVVPTLIRDMGDGTFHRLEGSININYFEDAVAQQQGSDRLNNRVGPIWRIEEISLIDEMKARMQKIDWEAKKRAAVANFWRNQTMHSLPPASKDESWMIDPTVRVVKDVVDPSGNVLAKAGTVVNPLAQVYAPLRMIVINPQSQLELEWAKQYREKHPFEGQTMILATDYSRDQGWDVMNRANEYLQTRTRLVPRELIERFHLTATPTVVATSGKVFAVQQFAINPTQESQQ
>NZ_CP038449.1|WP_171270097.1|161179_161686_+|signal-peptidase-I
MDKSTSYFRKRDVATLTAAAVATFFLFKSNFVIGMPTSQFSGCLSQKIFLVSKNEREVVRGGIYAISLDRDLRIARRGAKLIKIVAATGGDTVRVEDDGIWVNEKIFLPVPLQGIAERLQIDLSDLKKTITVPPHQLYLVGNTDKSYDSRFWGTIDEKNVIGRAVTFW
>NZ_CP038449.1|WP_171270098.1|155352_156009_+|hypothetical-protein
MASELLKSSAVQKQLGGCQVVYQQRIVPAMRAGFGSWIIWLSIPHCRDPHYIASITLKGEMMGLSTRIHEAKGFTYQKAKELMNKLNKSPDTPARLQMVQCTTEHASGSLPTDGLRNGYEQAVLRSALAMIAEPQQLLARGADGDYRVAVIQSGWWAYQIAGRGNKTCSWQFDDSGQWRSGCGQFMRLPNTPSLCGLAFCSFCGSRLSVQDNDDEYRE
>NZ_CP038449.1|WP_171270099.1|155114_155378_+|hypothetical-protein
MNELTADNATHYLRCRHVLGHGVTNYRMRCHVIKTMPDGRLKVQVYGERYWNDERREKSKFRYVEAARVTEIEQKSRSGDGQRALEK
>NZ_CP038449.1|WP_171270100.1|154100_154661_+|hypothetical-protein
MNEYLVKTTLHSFYVEAIDSDAACLAANTEIAGRDMPIPSQRAELYLVTNGGESFTGTFELEGIPFPKTWTEMNALRTRVFEAAKKDSHENWDLPVVRSRGAVLVVEDGQGETLIATGDCYQMPRTQKGYKEALNQIRSMNPSARRVWLCIGCDGAESVRSLNDGDYTPWSGEAQALIHEFESCAV
>NZ_CP038449.1|WP_171270177.1|170002_170851_-|CRISPR-associated-protein-Csf2
MYNQDNGHKPFDLAEHFLLAQGVDIVGDVAAPVDGEVDGDRHLREGNPMISIFGLWGLSSKANIGNAFPITPDSTAMFGGGARTIMFERSPELLDTLDQTERDRLQVILEEQAMASVDIAEIKAKSSELKKKLKTCSAEEKKDIFNELSVLDAEIQARKDAKTEARESIRRPIDQYEAITAGTVMEHRIGLKGVNMIELGFFLAALLEFARSPRMGGHLAHGCGLVSGSWEVKTWQPKSMVPVTVGKVEFDQDGFRLEGDVLKEAYQAWCDDVTSSFNKKAS
>NZ_CP038449.1|WP_171270090.1|171043_171748_-|hypothetical-protein
MPNFQSFRMVMALRTPVVLTDFPPTLDALVYEALSQRSPASSRNDLLLELRDYLAFSEQFGVFHASAMRFGVTMDCGLLTGSYVRTDRHTDDKLSSAMFAPNGAKGRYARLNLRGGPTKNRLREMPAYRAPFAFFDGYGDPWAIKSLLEFFVIGLGYDAQNSQMGAFGEVVIAPLPEDSSLLLQGKANRPLPASSGVEGIPGQSPLTPPYYLKNEKQTVVAPLRVRSEMLNTLL
>NZ_CP038449.1|WP_171270089.1|171747_173700_-|DEAD/DEAH-box-helicase
MTIEEPLDITSATFGALMCAAGLEARAEQSQYAIMAEAALSDLSKIGLLHADTGLGKSLGYLIPAMQRVYSDPRHPRIIVATHSHALMQQLLEKDCAILTRIARAYGVIPLTVGRLLGRVNFVSPERVDAAVQGLELSALDSRMLADLRTWSGTIAEYEDEFGGLPCELLASQICMTNDCDNEELDAMQRREVACDIVVTTHAMVAIDMLRGNAVLKGLDRPTMLIVDEADALAGQLQEWTQRRLNLVRFYGSLRDHLSMRHLQPLESAIADIKALLGDRHYAWDSELAGIARGILSMLSKLVKLKGLDETLVNTLEQQLRAVTAPTLGLGVSHERHEPAIVALNPWFAKNFGRYASTHFDSAMLTSGTLSITPDPVNGTAWIRHDLGIDETMLGVNAIFSPHHYGHMTLSLAGPGFPQIYGKHEKGGDQSPPLSDAWLQAVAHHITNRPGRVVVLTVSHEESRKLAKLLTGIERRPLLVHQQGEPLKHVIAEFSNLSSHHKGAVMLTAAGHTGLNIVDTQGAVGFDRLVLTRIAYAKPRTAEIDAMASYYLTTQKRDVKKMLQRQEHIRTANAAIRLMRQALGRGIRSPDDCIAVDICDPRFPLSHDLSSRHAKMRNIIPPRFLAEYQRAGLLLSNSDIHQPAPEEVFF
>NZ_CP038449.1|WP_171270011.1|173699_174275_-|hypothetical-protein
MMTYYENSLKLRETSPDHPYLAHQRLDYLMQEQLHNKVPYGWKREWISSEPRATQITLRTGFPLGLPGERKEELRLNVGDVLMFQMNFCCPVMTSITGKKNKKMSLLSDEDLPSALAKYCIKAGMLLQSHALASAYVELFRKASTRFPLKCHAISVIVEISDVALAEQAIVYGMGKKRVFGYGLPTAIEVL
>NZ_CP038449.1|WP_171270088.1|174271_175069_-|hypothetical-protein
MPDPIELLYNNLTRILESALGKSEHTDAACTCCQRPAKAFGHVGYTGIDSYKLPYTHCTACRAMSVTDIEIMGIERSAGSKFLGHKFGMFSGVGWVHEIESGRSTLLAPPGVYVKLPASFLEQITVIEMTIAGHLPWIAANASFPLLYIESFGRKTGALMRGLTISPSPQTLYCCSDAGMDSVTRVNSTIDLQGSLKLAEGLSVLPTPERNSFVKLVRDLSSGRITPRIATEQIGKNPAFGPLFRLLPADPHQRLKQVSIAEKLR
>NZ_CP038449.1|WP_171270087.1|175208_175517_-|hypothetical-protein
MTTSSEITVPKKSDLEIGYAIQARKAIKQAMESMGLTSGTLFVLLYGRPPEGNEEQTLRNRLNRGNPGADFIGLCVSKMPPLQTMAMADFYDLTAPEESTSS
>NZ_CP038449.1|WP_171270086.1|175699_176242_+|hypothetical-protein
MKLTRAALLVLSMVGLYACGGGDGDTGQDSGITPPAAPSSVREALLQMDADGTAPKLNRDADVAGPDVDGNGVRDDLDAYINSLPDTEPQKKALRQGYRVLRNLLLLDTTDTTAVLDGMRNSGASIWCIYSRYGSDAYEKSGEVEKYSVNTEERFKAYARFNAAASGHSAVMPRGDGCDE
>NZ_CP038449.1|WP_171270176.1|177104_177539_+|hypothetical-protein
MLETPTTGGNEGAFTATLTWTGPGDVDLHTNEPSGAHVFYRNTAGVSGFLDVDNTSGYGPEHYYATCDSDALNEGTYSIGINNYNAVNGGVATVQIATSKGGVIGTKTEVVGQVMGDAGNNSPVQMLDVVVSKDENGAVSFKVQ
>NZ_CP038449.1|WP_171270085.1|177784_178054_+|radical-SAM-protein
MNADYFVIACIFGVFGWGASEYLKARERKRVHTEVQKAIDSLRKKGFDVTFNRLAGFDQETAWEMEKVRSAGYSVTQAGKPITLSKQPR
>NZ_CP038449.1|WP_171270084.1|178063_178303_+|hypothetical-protein
MSSYFRDITPDVESVVPEEYQGRCKLICDNSFAVFPSLEQAERAACIAVNPTVGGYSDVRIEVTTEEITHDTVDDWFLD

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Crispr_ID: NZ_CP038449_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038449_3

180257-180650

TypeIV-A

Consensus_repeat	Method
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	PILER-CR
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	CRISPRCasFinder
GTCTCTCCCGNNCGCGGGAGGGTTAACG	CRT

6 spacers

The CRISPR arrays of NZ_CP038449_3

>merge|NZ_CP038449|3|180257-180650|PILER-CR,CRISPRCasFinder,CRT
GGTCTCTCCCGTGCGCGGGAGGGTTAACGGCCTACGGCGGGGAAACCAGCGAGCTGGTCGAGGTCTCTCCCGTGCGCGGGAGGGTTAACGGGCGGCCAGTTCGGCAGCCAGGGAAGGATCGCGGTCTCTCCCGTGCGCGGGCGGGTTAACGGAGTTGCTGGATTGTTTCGAGTTGGTCGTTATAGGTCTCTCCCGTGCGCGGGAGGGTTAACGGGCGCTGACCGCCGCACAGCGAGCTGCCCCCGCGTCTCTCCCGCACGCGGGAGGGTTAACGGATCTCCCACCCAATTCTCACCGTGATAAAGTCTCTCCCGCACGCGGGAGGGTTAACGTCTATTTTGGTCACCGTTACCAAAAAGGATTCCGTCTCTCCCGCACGCGGGAGAGTTACCGA

>NZ_CP038449|3|2|180257-180470|PILER-CR
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	CCTACGGCGGGGAAACCAGCGAGCTGGTCGA
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	GCGGCCAGTTCGGCAGCCAGGGAAGGATCGC
GGTCTCTCCCGTGCGCGGGCGGGTTAACGG	AGTTGCTGGATTGTTTCGAGTTGGTCGTTATA
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG

>NZ_CP038449|3|3|180257-180650|CRISPRCasFinder
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	CCTACGGCGGGGAAACCAGCGAGCTGGTCGA
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	GCGGCCAGTTCGGCAGCCAGGGAAGGATCGC
GGTCTCTCCCGTGCGCGGGCGGGTTAACGG	AGTTGCTGGATTGTTTCGAGTTGGTCGTTATA
GGTCTCTCCCGTGCGCGGGAGGGTTAACGG	GCGCTGACCGCCGCACAGCGAGCTGCCCCCG
CGTCTCTCCCGCACGCGGGAGGGTTAACGG	ATCTCCCACCCAATTCTCACCGTGATAA
AGTCTCTCCCGCACGCGGGAGGGTTAACGT	CTATTTTGGTCACCGTTACCAAAAAGGATTC
CGTCTCTCCCGCACGCGGGAGAGTTACCGA

>NZ_CP038449|3|2|180258-180649|CRT
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GCCTACGGCGGGGAAACCAGCGAGCTGGTCGAG
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGCGGCCAGTTCGGCAGCCAGGGAAGGATCGCG
GTCTCTCCCGTGCGCGGGCGGGTTAACG	GAGTTGCTGGATTGTTTCGAGTTGGTCGTTATAG
GTCTCTCCCGTGCGCGGGAGGGTTAACG	GGCGCTGACCGCCGCACAGCGAGCTGCCCCCGC
GTCTCTCCCGCACGCGGGAGGGTTAACG	GATCTCCCACCCAATTCTCACCGTGATAAA
GTCTCTCCCGCACGCGGGAGGGTTAACG	TCTATTTTGGTCACCGTTACCAAAAAGGATTCC
GTCTCTCCCGCACGCGGGAGAGTTACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038449.1\|WP_171270072.1\|193849_194980_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271180
NZ_CP038449.1\|WP_171270079.1\|181899_182925_-\|DGQHR-domain-containing-protein	unknown	unknown	gnl\|CDD\|319269
NZ_CP038449.1\|WP_171270082.1\|178966_179638_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP038449.1\|WP_171270075.1\|186773_187436_+\|RES-family-NAD+-phosphorylase	unknown	unknown	gnl\|CDD\|378053
NZ_CP038449.1\|WP_171270074.1\|187647_188295_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|222854
NZ_CP038449.1\|WP_171270084.1\|178063_178303_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270083.1\|178328_178604_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171277320.1\|194976_195273_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270011.1\|173699_174275_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270078.1\|183076_183265_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270086.1\|175699_176242_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270076.1\|185908_186787_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270087.1\|175208_175517_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270176.1\|177104_177539_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227021
NZ_CP038449.1\|WP_171270073.1\|188281_188593_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP038449.1\|WP_171270077.1\|183257_185831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235877
NZ_CP038449.1\|WP_171270081.1\|179619_180147_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270080.1\|180710_181817_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274805
NZ_CP038449.1\|WP_171270085.1\|177784_178054_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|367788
NZ_CP038449.1\|WP_171270088.1\|174271_175069_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP038449.1\|WP_171270074.1\|187647_188295_+\|AAA-family-ATPase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	6.56323e-30
NZ_CP038449.1\|WP_171270072.1\|193849_194980_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271180	cd00799, INT_Cre_C, C-terminal catalytic domain of Cre recombinase (also called integrase). Cre-like recombinases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre recombinase maintains the circular phage replicon in a monomeric state by catalyzing a site-specific recombination between two loxP sites. The catalytic core domain of Cre recombinase is linked to a more divergent helical N-terminal domain, which interacts primarily with the DNA major groove proximal to the crossover region.	1.00693e-27
NZ_CP038449.1\|WP_171270082.1\|178966_179638_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.07742e-09
NZ_CP038449.1\|WP_171270176.1\|177104_177539_+\|hypothetical-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	2.75435e-08
NZ_CP038449.1\|WP_171270075.1\|186773_187436_+\|RES-family-NAD+-phosphorylase	gnl\|CDD\|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	1.06741e-15
NZ_CP038449.1\|WP_171270077.1\|183257_185831_+\|hypothetical-protein	gnl\|CDD\|235877	PRK06850, PRK06850, hypothetical protein; Provisional.	3.76476e-17
NZ_CP038449.1\|WP_171270073.1\|188281_188593_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.00336461
NZ_CP038449.1\|WP_171270085.1\|177784_178054_+\|radical-SAM-protein	gnl\|CDD\|367788	pfam04055, Radical_SAM, Radical SAM superfamily. Radical SAM proteins catalyze diverse reactions, including unusual methylations, isomerisation, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation.	0.000561189
NZ_CP038449.1\|WP_171270080.1\|180710_181817_-\|hypothetical-protein	gnl\|CDD\|274805	TIGR03830, transcriptional_regulator_XRE_family, putative zinc finger/helix-turn-helix protein, YgiT family. This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.	4.04938e-05
NZ_CP038449.1\|WP_171270079.1\|181899_182925_-\|DGQHR-domain-containing-protein	gnl\|CDD\|319269	cd16412, dndB, DNA sulfur modification protein DndB. dndB acts in the regulation of DNA modifications, including DNA phosphorothioation. DndB may act by binding near the phosphorothioate modification site and regulating access of the Dnd modification machinery to DNA. These proteins show similarity to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, and other members of the ParB/Srx superfamily.	4.23101e-26

>NZ_CP038449.1|WP_171270081.1|179619_180147_-|hypothetical-protein
MKHVHIEITFGFTFPLAQSSHQPVQLLWLASTSVGLTSTPPDKLSIEDVNFDPSIINPVLDATQIPVIATSPRSRRAAFVDPLLPPQFLTLHHSHLGCYFSTDPLITGRTEIVVGDRLGDMDLLAIEPDIELLVVITKSATDGIHGLMIGKQLACNEPPHHIAQGAVATSHRMDT
>NZ_CP038449.1|WP_171270082.1|178966_179638_+|CPBP-family-intramembrane-metalloprotease
MNSSKLNRFIVVVTSVAIFIFWTLLFALVYSSAKSHGLSKDACQMLGALSGVMFLLVIAIPYHKWIAPLEVGRALQRRSILPMILVVVLYLGCFGYESLTGQPPEPWMVDFLGKSGWQMFLALVSSLVLAPIGEEILFRGILLNMFGSSRTWILGIGVVLVALFFAWTHTQYQSTSTVALLFALSVVFSWARLRSGGLLLPVLLHSLASVLGIVVGWIQVSIL
>NZ_CP038449.1|WP_171270083.1|178328_178604_+|hypothetical-protein
MRKTLEYSGEFIALLIVLAFYSMACVWMLLGDGVKTVYPSLYEMLVSRYKMLPVTAAEVGENPNGLDLIRLSQKAEKWYLTMQVETKKKEE
>NZ_CP038449.1|WP_171270084.1|178063_178303_+|hypothetical-protein
MSSYFRDITPDVESVVPEEYQGRCKLICDNSFAVFPSLEQAERAACIAVNPTVGGYSDVRIEVTTEEITHDTVDDWFLD
>NZ_CP038449.1|WP_171270085.1|177784_178054_+|radical-SAM-protein
MNADYFVIACIFGVFGWGASEYLKARERKRVHTEVQKAIDSLRKKGFDVTFNRLAGFDQETAWEMEKVRSAGYSVTQAGKPITLSKQPR
>NZ_CP038449.1|WP_171270176.1|177104_177539_+|hypothetical-protein
MLETPTTGGNEGAFTATLTWTGPGDVDLHTNEPSGAHVFYRNTAGVSGFLDVDNTSGYGPEHYYATCDSDALNEGTYSIGINNYNAVNGGVATVQIATSKGGVIGTKTEVVGQVMGDAGNNSPVQMLDVVVSKDENGAVSFKVQ
>NZ_CP038449.1|WP_171270086.1|175699_176242_+|hypothetical-protein
MKLTRAALLVLSMVGLYACGGGDGDTGQDSGITPPAAPSSVREALLQMDADGTAPKLNRDADVAGPDVDGNGVRDDLDAYINSLPDTEPQKKALRQGYRVLRNLLLLDTTDTTAVLDGMRNSGASIWCIYSRYGSDAYEKSGEVEKYSVNTEERFKAYARFNAAASGHSAVMPRGDGCDE
>NZ_CP038449.1|WP_171270087.1|175208_175517_-|hypothetical-protein
MTTSSEITVPKKSDLEIGYAIQARKAIKQAMESMGLTSGTLFVLLYGRPPEGNEEQTLRNRLNRGNPGADFIGLCVSKMPPLQTMAMADFYDLTAPEESTSS
>NZ_CP038449.1|WP_171270088.1|174271_175069_-|hypothetical-protein
MPDPIELLYNNLTRILESALGKSEHTDAACTCCQRPAKAFGHVGYTGIDSYKLPYTHCTACRAMSVTDIEIMGIERSAGSKFLGHKFGMFSGVGWVHEIESGRSTLLAPPGVYVKLPASFLEQITVIEMTIAGHLPWIAANASFPLLYIESFGRKTGALMRGLTISPSPQTLYCCSDAGMDSVTRVNSTIDLQGSLKLAEGLSVLPTPERNSFVKLVRDLSSGRITPRIATEQIGKNPAFGPLFRLLPADPHQRLKQVSIAEKLR
>NZ_CP038449.1|WP_171270011.1|173699_174275_-|hypothetical-protein
MMTYYENSLKLRETSPDHPYLAHQRLDYLMQEQLHNKVPYGWKREWISSEPRATQITLRTGFPLGLPGERKEELRLNVGDVLMFQMNFCCPVMTSITGKKNKKMSLLSDEDLPSALAKYCIKAGMLLQSHALASAYVELFRKASTRFPLKCHAISVIVEISDVALAEQAIVYGMGKKRVFGYGLPTAIEVL
>NZ_CP038449.1|WP_171270080.1|180710_181817_-|hypothetical-protein
MLNAFHIPQLYLEPGHVRAVRLYLSELHKMETPVTQAEFAKLFGITATNTVGRYERGDIQAPVMLLRFMQTQIHLTHQLFGLYENEQQSIELFQSYLTTLSTDNTASTTPGGATKLPNRSVVSDPMFLRTLYENAWGFGGLVVDRFTLRLGRDPLTITPAFGRKKNLRSHGLFLLDQAIREEGEERMSAQDMQLMRDKLNSLTPDGCLTRTRVVKFPHFSVRVLNNVMTIVIEKAERKALLNTRLIETGRQAEQDATKDLLQRELKEGFKTLLANCKLIDETERLKNFIGTDKRVKFHFIGQLEQILRQWLCLPTPDPTEIASHKLWLSMRAGETACTTDLLKLKVVGRDLEIQFTELARKALGEIYS
>NZ_CP038449.1|WP_171270079.1|181899_182925_-|DGQHR-domain-containing-protein
MTIRIVAFKGTFGRFDTFTSSVSTRALGEIFADYYAGIAEAEDPQMRAQRALDMAHVRKIMSYLDRSVRAFGSPIATAKVLNVRPLAGVDNLVEVELEDPYLVDGQKRIKACILRSESDAQWEDSIPLHIVATSDLRDKQQLFSSINSTAAKVSPSLNAIYDHANPLSTFIPQNCPAEVLECEKSIVSKSSSKLVTPAIFKEAMAILLGVSIKQLGALSLDKMEASWDRWHPYMTELWAVYKVLAENAGGLTELRELSILPHNVGFLAIVRLFPLMQDPAQLRGLIELERDGLTSRTSGLWDGRCVMLGAIKKSGESVPLTAAMLGTQLKLELDDNLKLFL
>NZ_CP038449.1|WP_171270078.1|183076_183265_+|hypothetical-protein
MLVRATLRKHKGTEPLRLCSSSATFHTLLTRWADASGHALFPILKPVQGERWILDVQVVTHA
>NZ_CP038449.1|WP_171270077.1|183257_185831_+|hypothetical-protein
MLKHVVGLAEVEATLLGGELAVANIDPRREVIFGAAQELFDELVEERIIPLIQQHIVRVASSFGKDSTLLLAIMVEGHRRARARGLPVAGPLIVTHGDTRIESPVMSTYAMRQMRLLESYLDREGVDHRLICAEPFDRYSWPVMYCGGLKLLTVGASASADCSIVLKQDPLKRVERELAQEFPGIVTATGVRLDESTNRAQSIRELGLDKGLVVIHGSNRDVAPIVDLETADVWLLLRCMGEGAHREYGNHLPYWDSSTFYLRRMYDDQDESQCPITGSSSLGSKTGCGGSSLRGGCALCTVVNNDKQAESLTDLPQFPQLANLLAIRNWLSRNFYNMNYRRFIARKPTDDGFLKLQANTFNEAWMTSVLRWLLQADRDEQQRAADFSQRLLTGEWISDKGVQAILTDAKLTPAQRVEWLRWYLEDMANPTFELVTPTQLLMIDAIWSRDGYRLAPFAALAIWKEVYHQGVSVPYPDLDGERFKESIPAPVYLPIGHDPELRSLADIEATGVFDRYLVDLESLSFGSCGGATKRVRREVITPAIQYGDERGAQFSGWFGDTVTVANVVQADSGECGYTIDEEAAFWITGSMIDEYLGDQHELERRSGIALRRLISEGVLRLSVQAMRNSARMMARAELYERAGMSRLEDGNPVLLAQCISQSEYDKQLVANPSSDNKAMPSCFVWNTPINVQWADLEAAVEAVLNLHLSLEFRRSVVAFTLSQMGSAWQFDGVQYRELQQVIAQQVQSIQLLFSKPERLLALLPANATLQKGRSREQNMRLRQLQQQALHVLHQHRTEALAALDAALGEWGETVEEGINPVFVAKGGMGFMKDVAQARAYVAHLQLLYGYSRLAKAC
>NZ_CP038449.1|WP_171270076.1|185908_186787_+|hypothetical-protein
MSKTLARGAHVVTDTSRHNSRPIISVLDQNSLRDSLSGTIQGSRREVAGRVYSGVRTGRAKFKKAVAGEAMSAARQLYFLMDASAPTLRNIPLEIIQNLMPQAIEMALLQILMQQPDSGPAIRDGVWSMVAAEESVGIATEAKSASKQTPVNEQPTERHKFKVATPAQLRDQVLSRGEWLTAQEVSENAGYQNANPSVQPNKWKKAGKIFAITVDGKDRFPAYALGVDGKPLPQMAEVLSVLGPHRQPLAIASWFASANSWLGSKTPMESIADNPQGVLKAAKMEVAPIEHG
>NZ_CP038449.1|WP_171270075.1|186773_187436_+|RES-family-NAD+-phosphorylase
MSTDKKFPQPPENLKVKTETVAAGTKMWRVHHSQFGEAAFNPGFGNARFSPIDNASGEKIPTLYAGESIDVALMESVFHDVPHSGDLKTYSISKFDGQMISELILTDDVLMAKLHGAALRHLGIKEADLIHSDASEYPHTRAWAEKIYASKPEVQGLKWDSKQVGGPAYLFFGDRVAENVFNVSTPGTLLTESPEAVKRIEHLVDEMGVQLVDPDTPDTE
>NZ_CP038449.1|WP_171270074.1|187647_188295_+|AAA-family-ATPase
MITIIGCNKGGAGKSTTAVNVAIALAMRGFDVVLVDADFQRSAAKWYGYRQENNIQPSITLIEKRDNISQTLKQLDEKYDHVIVDVAGKNSREFITGGTVAHQIIAPHQCSQFDLETLIELEQQVTYMRDLNPDLKVYLYQTMATTNPILRGTERHEFLEFLKFYDQMTPLKSVACTRKSYRDAIPTGHAVVELNNPKAKQEVLDLIEEVFDGAA
>NZ_CP038449.1|WP_171270073.1|188281_188593_+|CopG-family-transcriptional-regulator
MAPLKNPKDKGGATPSSTRPTVSPEDADRLADQLADKPYGSEPKVRDTLRRTSISLPESMLHRCEELAFDNKRSGKHPRSVSAIVLEALNRYYGIGESENRTK
>NZ_CP038449.1|WP_171270072.1|193849_194980_-|tyrosine-type-recombinase/integrase
MSELIPAQQNLPSSELQSSQVPIDFNQLRPDGLADLMSKGWLRGVHLENDPQIQAVMQRFLNEFRESEERYSPRTLLQLTCMWEQFAEWCVENNEPYLPAKIETVKRYLSQRARDKHRNTLLLDKWSISRNHRACGCPDPTTDQSVKDLMAALIRTKVMADESIEQASAMRECHIDELVQIWGGSEHLADRRDIAMLVVAYESLLRSKELANIRIKHLQVKSDGSGLLTIPITKTNKSGEPDYVYLSRQAVRLIREYMSAAGRSLVVHPERPDEPLFGGLNRVGKSVKVIKVMTYTTIYKIFSRAWEALDLESVGIPRFSAHSARVGAAQDLAANGYNSLQIMMSGRWASEVMVGRYCRNIFAEEGAMAKMRHGRR
>NZ_CP038449.1|WP_171277320.1|194976_195273_-|hypothetical-protein
MQLRCSFDAYVIGDMFLMVVDRDEPLFANVTNDTEAVIAWLNRRLDGGVGLRRIIYSDSYGNFAEIMAKCGKFTGFKACTQSQQAYFISVLPLGEQLL

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Crispr_ID: NZ_CP038449_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038449_4

189131-189586

TypeIV-A

Consensus_repeat	Method
GTCTCTCCCGCACGCGGGAGGGTTAACGG	PILER-CR
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CRISPRCasFinder
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CRT

7 spacers

The CRISPR arrays of NZ_CP038449_4

>merge|NZ_CP038449|4|189131-189586|PILER-CR,CRISPRCasFinder,CRT
GTCTCTCCCGCACGCGGGAGGGTTAACGGGGCACGCGCCGCGCCCTGACCCACCTGCGGGCGTCTCTCCCGCACGCGGGAGGGTTAACGGCCCGCCGACGAGGAGATCGCGACATTCCTCCAGTCTCTCCCGCACGCGGGAGGGTTAACGGACGGCACCGGCATCGATGCGCGACTCGGCGGTGTCTCTCCCGCTCGCGGGAGGGTTAACGGCCATCGGACTCGACCGCATCGGAGGCGCCCACGTCTCTCCCGCACGCGGGAGGGTTAACGGCCCAAGACGATCGCGCCCACGCCCACGACGGCGTATCTCCCGCACGCGGGAGGGTTAACGGTACCAGCTCAAGATCAGAGGGCTTTCCTTGGCGCCTCTCCTGCACGCGGGAGGGTTAACGGTTCAACCCGGCATGTGAACGCCATAAGCTGACGTCCCTCCCGCACGCGGAAGGGTTTACTT

>NZ_CP038449|4|3|189131-189525|PILER-CR
GTCTCTCCCGCACGCGGGAGGGTTAACGG	GGCACGCGCCGCGCCCTGACCCACCTGCGGGC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCGCCGACGAGGAGATCGCGACATTCCTCCA
GTCTCTCCCGCACGCGGGAGGGTTAACGG	ACGGCACCGGCATCGATGCGCGACTCGGCGGT
GTCTCTCCCGCTCGCGGGAGGGTTAACGG	CCATCGGACTCGACCGCATCGGAGGCGCCCAC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCAAGACGATCGCGCCCACGCCCACGACGGC
GTATCTCCCGCACGCGGGAGGGTTAACGG	TACCAGCTCAAGATCAGAGGGCTTTCCTTGGC
GCCTCTCCTGCACGCGGGAGGGTTAACGG

>NZ_CP038449|4|4|189131-189586|CRISPRCasFinder
GTCTCTCCCGCACGCGGGAGGGTTAACGG	GGCACGCGCCGCGCCCTGACCCACCTGCGGGC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCGCCGACGAGGAGATCGCGACATTCCTCCA
GTCTCTCCCGCACGCGGGAGGGTTAACGG	ACGGCACCGGCATCGATGCGCGACTCGGCGGT
GTCTCTCCCGCTCGCGGGAGGGTTAACGG	CCATCGGACTCGACCGCATCGGAGGCGCCCAC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCAAGACGATCGCGCCCACGCCCACGACGGC
GTATCTCCCGCACGCGGGAGGGTTAACGG	TACCAGCTCAAGATCAGAGGGCTTTCCTTGGC
GCCTCTCCTGCACGCGGGAGGGTTAACGG	TTCAACCCGGCATGTGAACGCCATAAGCTGAC
GTCCCTCCCGCACGCGGAAGGGTTTACTT

>NZ_CP038449|4|3|189131-189586|CRT
GTCTCTCCCGCACGCGGGAGGGTTAACGG	GGCACGCGCCGCGCCCTGACCCACCTGCGGGC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCGCCGACGAGGAGATCGCGACATTCCTCCA
GTCTCTCCCGCACGCGGGAGGGTTAACGG	ACGGCACCGGCATCGATGCGCGACTCGGCGGT
GTCTCTCCCGCTCGCGGGAGGGTTAACGG	CCATCGGACTCGACCGCATCGGAGGCGCCCAC
GTCTCTCCCGCACGCGGGAGGGTTAACGG	CCCAAGACGATCGCGCCCACGCCCACGACGGC
GTATCTCCCGCACGCGGGAGGGTTAACGG	TACCAGCTCAAGATCAGAGGGCTTTCCTTGGC
GCCTCTCCTGCACGCGGGAGGGTTAACGG	TTCAACCCGGCATGTGAACGCCATAAGCTGAC
GTCCCTCCCGCACGCGGAAGGGTTTACTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038449.1\|WP_171270070.1\|195501_195660_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270072.1\|193849_194980_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271180
NZ_CP038449.1\|WP_171270079.1\|181899_182925_-\|DGQHR-domain-containing-protein	unknown	unknown	gnl\|CDD\|319269
NZ_CP038449.1\|WP_171270082.1\|178966_179638_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP038449.1\|WP_171270075.1\|186773_187436_+\|RES-family-NAD+-phosphorylase	unknown	unknown	gnl\|CDD\|378053
NZ_CP038449.1\|WP_171270074.1\|187647_188295_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|222854
NZ_CP038449.1\|WP_171270073.1\|188281_188593_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NZ_CP038449.1\|WP_171270068.1\|196714_198403_-\|DUF4942-domain-containing-protein	unknown	unknown	gnl\|CDD\|372683
NZ_CP038449.1\|WP_171277320.1\|194976_195273_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270078.1\|183076_183265_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270076.1\|185908_186787_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270077.1\|183257_185831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235877
NZ_CP038449.1\|WP_171270081.1\|179619_180147_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038449.1\|WP_171270069.1\|196256_196658_+\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|182380
NZ_CP038449.1\|WP_171270080.1\|180710_181817_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274805

Protein	Function_ID	Function_description	E-value
NZ_CP038449.1\|WP_171270077.1\|183257_185831_+\|hypothetical-protein	gnl\|CDD\|235877	PRK06850, PRK06850, hypothetical protein; Provisional.	3.76476e-17
NZ_CP038449.1\|WP_171270072.1\|193849_194980_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271180	cd00799, INT_Cre_C, C-terminal catalytic domain of Cre recombinase (also called integrase). Cre-like recombinases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre recombinase maintains the circular phage replicon in a monomeric state by catalyzing a site-specific recombination between two loxP sites. The catalytic core domain of Cre recombinase is linked to a more divergent helical N-terminal domain, which interacts primarily with the DNA major groove proximal to the crossover region.	1.00693e-27
NZ_CP038449.1\|WP_171270079.1\|181899_182925_-\|DGQHR-domain-containing-protein	gnl\|CDD\|319269	cd16412, dndB, DNA sulfur modification protein DndB. dndB acts in the regulation of DNA modifications, including DNA phosphorothioation. DndB may act by binding near the phosphorothioate modification site and regulating access of the Dnd modification machinery to DNA. These proteins show similarity to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, and other members of the ParB/Srx superfamily.	4.23101e-26
NZ_CP038449.1\|WP_171270082.1\|178966_179638_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.07742e-09
NZ_CP038449.1\|WP_171270075.1\|186773_187436_+\|RES-family-NAD+-phosphorylase	gnl\|CDD\|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	1.06741e-15
NZ_CP038449.1\|WP_171270074.1\|187647_188295_+\|AAA-family-ATPase	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	6.56323e-30
NZ_CP038449.1\|WP_171270073.1\|188281_188593_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	0.00336461
NZ_CP038449.1\|WP_171270068.1\|196714_198403_-\|DUF4942-domain-containing-protein	gnl\|CDD\|372683	pfam13708, DUF4942, Domain of unknown function (DUF4942). The function of this family is not known.	1.39308e-31
NZ_CP038449.1\|WP_171270069.1\|196256_196658_+\|H-NS-histone-family-protein	gnl\|CDD\|182380	PRK10328, PRK10328, DNA-binding protein StpA.	3.95278e-35
NZ_CP038449.1\|WP_171270080.1\|180710_181817_-\|hypothetical-protein	gnl\|CDD\|274805	TIGR03830, transcriptional_regulator_XRE_family, putative zinc finger/helix-turn-helix protein, YgiT family. This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.	4.04938e-05

>NZ_CP038449.1|WP_171270073.1|188281_188593_+|CopG-family-transcriptional-regulator
MAPLKNPKDKGGATPSSTRPTVSPEDADRLADQLADKPYGSEPKVRDTLRRTSISLPESMLHRCEELAFDNKRSGKHPRSVSAIVLEALNRYYGIGESENRTK
>NZ_CP038449.1|WP_171270074.1|187647_188295_+|AAA-family-ATPase
MITIIGCNKGGAGKSTTAVNVAIALAMRGFDVVLVDADFQRSAAKWYGYRQENNIQPSITLIEKRDNISQTLKQLDEKYDHVIVDVAGKNSREFITGGTVAHQIIAPHQCSQFDLETLIELEQQVTYMRDLNPDLKVYLYQTMATTNPILRGTERHEFLEFLKFYDQMTPLKSVACTRKSYRDAIPTGHAVVELNNPKAKQEVLDLIEEVFDGAA
>NZ_CP038449.1|WP_171270075.1|186773_187436_+|RES-family-NAD+-phosphorylase
MSTDKKFPQPPENLKVKTETVAAGTKMWRVHHSQFGEAAFNPGFGNARFSPIDNASGEKIPTLYAGESIDVALMESVFHDVPHSGDLKTYSISKFDGQMISELILTDDVLMAKLHGAALRHLGIKEADLIHSDASEYPHTRAWAEKIYASKPEVQGLKWDSKQVGGPAYLFFGDRVAENVFNVSTPGTLLTESPEAVKRIEHLVDEMGVQLVDPDTPDTE
>NZ_CP038449.1|WP_171270076.1|185908_186787_+|hypothetical-protein
MSKTLARGAHVVTDTSRHNSRPIISVLDQNSLRDSLSGTIQGSRREVAGRVYSGVRTGRAKFKKAVAGEAMSAARQLYFLMDASAPTLRNIPLEIIQNLMPQAIEMALLQILMQQPDSGPAIRDGVWSMVAAEESVGIATEAKSASKQTPVNEQPTERHKFKVATPAQLRDQVLSRGEWLTAQEVSENAGYQNANPSVQPNKWKKAGKIFAITVDGKDRFPAYALGVDGKPLPQMAEVLSVLGPHRQPLAIASWFASANSWLGSKTPMESIADNPQGVLKAAKMEVAPIEHG
>NZ_CP038449.1|WP_171270077.1|183257_185831_+|hypothetical-protein
MLKHVVGLAEVEATLLGGELAVANIDPRREVIFGAAQELFDELVEERIIPLIQQHIVRVASSFGKDSTLLLAIMVEGHRRARARGLPVAGPLIVTHGDTRIESPVMSTYAMRQMRLLESYLDREGVDHRLICAEPFDRYSWPVMYCGGLKLLTVGASASADCSIVLKQDPLKRVERELAQEFPGIVTATGVRLDESTNRAQSIRELGLDKGLVVIHGSNRDVAPIVDLETADVWLLLRCMGEGAHREYGNHLPYWDSSTFYLRRMYDDQDESQCPITGSSSLGSKTGCGGSSLRGGCALCTVVNNDKQAESLTDLPQFPQLANLLAIRNWLSRNFYNMNYRRFIARKPTDDGFLKLQANTFNEAWMTSVLRWLLQADRDEQQRAADFSQRLLTGEWISDKGVQAILTDAKLTPAQRVEWLRWYLEDMANPTFELVTPTQLLMIDAIWSRDGYRLAPFAALAIWKEVYHQGVSVPYPDLDGERFKESIPAPVYLPIGHDPELRSLADIEATGVFDRYLVDLESLSFGSCGGATKRVRREVITPAIQYGDERGAQFSGWFGDTVTVANVVQADSGECGYTIDEEAAFWITGSMIDEYLGDQHELERRSGIALRRLISEGVLRLSVQAMRNSARMMARAELYERAGMSRLEDGNPVLLAQCISQSEYDKQLVANPSSDNKAMPSCFVWNTPINVQWADLEAAVEAVLNLHLSLEFRRSVVAFTLSQMGSAWQFDGVQYRELQQVIAQQVQSIQLLFSKPERLLALLPANATLQKGRSREQNMRLRQLQQQALHVLHQHRTEALAALDAALGEWGETVEEGINPVFVAKGGMGFMKDVAQARAYVAHLQLLYGYSRLAKAC
>NZ_CP038449.1|WP_171270078.1|183076_183265_+|hypothetical-protein
MLVRATLRKHKGTEPLRLCSSSATFHTLLTRWADASGHALFPILKPVQGERWILDVQVVTHA
>NZ_CP038449.1|WP_171270079.1|181899_182925_-|DGQHR-domain-containing-protein
MTIRIVAFKGTFGRFDTFTSSVSTRALGEIFADYYAGIAEAEDPQMRAQRALDMAHVRKIMSYLDRSVRAFGSPIATAKVLNVRPLAGVDNLVEVELEDPYLVDGQKRIKACILRSESDAQWEDSIPLHIVATSDLRDKQQLFSSINSTAAKVSPSLNAIYDHANPLSTFIPQNCPAEVLECEKSIVSKSSSKLVTPAIFKEAMAILLGVSIKQLGALSLDKMEASWDRWHPYMTELWAVYKVLAENAGGLTELRELSILPHNVGFLAIVRLFPLMQDPAQLRGLIELERDGLTSRTSGLWDGRCVMLGAIKKSGESVPLTAAMLGTQLKLELDDNLKLFL
>NZ_CP038449.1|WP_171270080.1|180710_181817_-|hypothetical-protein
MLNAFHIPQLYLEPGHVRAVRLYLSELHKMETPVTQAEFAKLFGITATNTVGRYERGDIQAPVMLLRFMQTQIHLTHQLFGLYENEQQSIELFQSYLTTLSTDNTASTTPGGATKLPNRSVVSDPMFLRTLYENAWGFGGLVVDRFTLRLGRDPLTITPAFGRKKNLRSHGLFLLDQAIREEGEERMSAQDMQLMRDKLNSLTPDGCLTRTRVVKFPHFSVRVLNNVMTIVIEKAERKALLNTRLIETGRQAEQDATKDLLQRELKEGFKTLLANCKLIDETERLKNFIGTDKRVKFHFIGQLEQILRQWLCLPTPDPTEIASHKLWLSMRAGETACTTDLLKLKVVGRDLEIQFTELARKALGEIYS
>NZ_CP038449.1|WP_171270081.1|179619_180147_-|hypothetical-protein
MKHVHIEITFGFTFPLAQSSHQPVQLLWLASTSVGLTSTPPDKLSIEDVNFDPSIINPVLDATQIPVIATSPRSRRAAFVDPLLPPQFLTLHHSHLGCYFSTDPLITGRTEIVVGDRLGDMDLLAIEPDIELLVVITKSATDGIHGLMIGKQLACNEPPHHIAQGAVATSHRMDT
>NZ_CP038449.1|WP_171270082.1|178966_179638_+|CPBP-family-intramembrane-metalloprotease
MNSSKLNRFIVVVTSVAIFIFWTLLFALVYSSAKSHGLSKDACQMLGALSGVMFLLVIAIPYHKWIAPLEVGRALQRRSILPMILVVVLYLGCFGYESLTGQPPEPWMVDFLGKSGWQMFLALVSSLVLAPIGEEILFRGILLNMFGSSRTWILGIGVVLVALFFAWTHTQYQSTSTVALLFALSVVFSWARLRSGGLLLPVLLHSLASVLGIVVGWIQVSIL
>NZ_CP038449.1|WP_171270072.1|193849_194980_-|tyrosine-type-recombinase/integrase
MSELIPAQQNLPSSELQSSQVPIDFNQLRPDGLADLMSKGWLRGVHLENDPQIQAVMQRFLNEFRESEERYSPRTLLQLTCMWEQFAEWCVENNEPYLPAKIETVKRYLSQRARDKHRNTLLLDKWSISRNHRACGCPDPTTDQSVKDLMAALIRTKVMADESIEQASAMRECHIDELVQIWGGSEHLADRRDIAMLVVAYESLLRSKELANIRIKHLQVKSDGSGLLTIPITKTNKSGEPDYVYLSRQAVRLIREYMSAAGRSLVVHPERPDEPLFGGLNRVGKSVKVIKVMTYTTIYKIFSRAWEALDLESVGIPRFSAHSARVGAAQDLAANGYNSLQIMMSGRWASEVMVGRYCRNIFAEEGAMAKMRHGRR
>NZ_CP038449.1|WP_171277320.1|194976_195273_-|hypothetical-protein
MQLRCSFDAYVIGDMFLMVVDRDEPLFANVTNDTEAVIAWLNRRLDGGVGLRRIIYSDSYGNFAEIMAKCGKFTGFKACTQSQQAYFISVLPLGEQLL
>NZ_CP038449.1|WP_171270070.1|195501_195660_-|hypothetical-protein
MEGLRVEYPIDRVNFGIGIVTRYDEETDTAVVQDEDDGSFFKGPADKLVPIE
>NZ_CP038449.1|WP_171270069.1|196256_196658_+|H-NS-histone-family-protein
MSEVIKVITNIRSLRAALRELTIEQLEEAKEKFDAIYKERIDEHNAQLEEAKEHQRKLDEYAELLKSAGIDPRELINESAPTVEKRAQRAPRPPKYQYTENGENKTWTGQGRMPKAIAEAVEAGSDLNDFLIK
>NZ_CP038449.1|WP_171270068.1|196714_198403_-|DUF4942-domain-containing-protein
MIDYQFYPSDPILANRAFGKFSGSRIIRLLDPSAGRADLLLPAYQYLGGKSRIDCVEIDLDNQAILRSNGFRVVGTDFLKFKSAAIHSHILMNPPFNVGARHVIHAWNIASNAEIVAIINAETLRDPFSAERQHLVKLLEDHAGSEVEYIKHAFVNPDTQRRTNVEVALIHLIKRTASKFDTSYLAQLHQEKRREFGGDADYSEGRALMLPHDELQSRVIDFECAVDAMVAKHDALARYTHLSRRLGHAINSDTDEVKFESIEADRNKGINEDYDKLKAAAWSGIMKSTSVTKRISTNVAAQIEQEFEHIRQMEFSIENIFAFIDGLVAQTSVIQSEVMCEVFDRFSRYHTGNRCYYRSWKSNDKHRTQAHRLKMSRFVIPGVKRYYEGLSKPDFAWEDKQKFTDMDKAFALLDGKTPETIQGFEWALRTHVLELWRGERVSMDYFDLRFYPGVGTFHIYPKRKDLVDRLNDVVGRHRQWLPHDASQATPAFWAQYEQAELVASKLSLKGVSLQDLEHNDGHGGEVARASMDTALREAQLKVGIDYQPEQLEYQQTPVLMFA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	154374-154425	0	1.0
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	115336-115387	0	1.0
NZ_CP038449_2	2.1\|169380\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169380-169412	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100349-100381	0	1.0
NZ_CP038449_2	2.1\|169380\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169380-169412	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169380-169412	0	1.0
NZ_CP038449_2	2.2\|169441\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169441-169473	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169441-169473	0	1.0
NZ_CP038449_2	2.2\|169441\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169441-169473	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100288-100320	0	1.0
NZ_CP038449_2	2.3\|169502\|34\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169502-169535	34	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169502-169535	0	1.0
NZ_CP038449_2	2.3\|169502\|34\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169502-169535	34	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100226-100259	0	1.0
NZ_CP038449_2	2.4\|169564\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169564-169596	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169564-169596	0	1.0
NZ_CP038449_2	2.4\|169564\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169564-169596	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100165-100197	0	1.0
NZ_CP038449_2	2.5\|169625\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169625-169657	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169625-169657	0	1.0
NZ_CP038449_2	2.5\|169625\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169625-169657	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100104-100136	0	1.0
NZ_CP038449_2	2.6\|169686\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169686-169718	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169686-169718	0	1.0
NZ_CP038449_2	2.6\|169686\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169686-169718	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	100043-100075	0	1.0
NZ_CP038449_2	2.7\|169747\|33\|NZ_CP038449\|CRISPRCasFinder,CRT	169747-169779	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	169747-169779	0	1.0
NZ_CP038449_2	2.7\|169747\|33\|NZ_CP038449\|CRISPRCasFinder,CRT	169747-169779	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	99982-100014	0	1.0
NZ_CP038449_3	3.1\|180287\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180287-180317	31	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180287-180317	0	1.0
NZ_CP038449_3	3.1\|180287\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180287-180317	31	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89444-89474	0	1.0
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89383-89413	0	1.0
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180348-180378	0	1.0
NZ_CP038449_3	3.3\|180409\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180409-180440	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180409-180440	0	1.0
NZ_CP038449_3	3.3\|180409\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180409-180440	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89321-89352	0	1.0
NZ_CP038449_3	3.4\|180471\|31\|NZ_CP038449\|CRISPRCasFinder	180471-180501	31	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180471-180501	0	1.0
NZ_CP038449_3	3.4\|180471\|31\|NZ_CP038449\|CRISPRCasFinder	180471-180501	31	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89260-89290	0	1.0
NZ_CP038449_3	3.5\|180532\|28\|NZ_CP038449\|CRISPRCasFinder	180532-180559	28	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180532-180559	0	1.0
NZ_CP038449_3	3.5\|180532\|28\|NZ_CP038449\|CRISPRCasFinder	180532-180559	28	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89202-89229	0	1.0
NZ_CP038449_3	3.6\|180590\|31\|NZ_CP038449\|CRISPRCasFinder	180590-180620	31	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180590-180620	0	1.0
NZ_CP038449_3	3.6\|180590\|31\|NZ_CP038449\|CRISPRCasFinder	180590-180620	31	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89141-89171	0	1.0
NZ_CP038449_3	3.7\|180286\|33\|NZ_CP038449\|CRT	180286-180318	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180286-180318	0	1.0
NZ_CP038449_3	3.7\|180286\|33\|NZ_CP038449\|CRT	180286-180318	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89443-89475	0	1.0
NZ_CP038449_3	3.8\|180347\|33\|NZ_CP038449\|CRT	180347-180379	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180347-180379	0	1.0
NZ_CP038449_3	3.8\|180347\|33\|NZ_CP038449\|CRT	180347-180379	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89382-89414	0	1.0
NZ_CP038449_3	3.9\|180408\|34\|NZ_CP038449\|CRT	180408-180441	34	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89320-89353	0	1.0
NZ_CP038449_3	3.9\|180408\|34\|NZ_CP038449\|CRT	180408-180441	34	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180408-180441	0	1.0
NZ_CP038449_3	3.10\|180470\|33\|NZ_CP038449\|CRT	180470-180502	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180470-180502	0	1.0
NZ_CP038449_3	3.10\|180470\|33\|NZ_CP038449\|CRT	180470-180502	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89259-89291	0	1.0
NZ_CP038449_3	3.11\|180531\|30\|NZ_CP038449\|CRT	180531-180560	30	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180531-180560	0	1.0
NZ_CP038449_3	3.11\|180531\|30\|NZ_CP038449\|CRT	180531-180560	30	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89201-89230	0	1.0
NZ_CP038449_3	3.12\|180589\|33\|NZ_CP038449\|CRT	180589-180621	33	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	180589-180621	0	1.0
NZ_CP038449_3	3.12\|180589\|33\|NZ_CP038449\|CRT	180589-180621	33	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	89140-89172	0	1.0
NZ_CP038449_4	4.1\|189160\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189160-189191	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189160-189191	0	1.0
NZ_CP038449_4	4.1\|189160\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189160-189191	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80570-80601	0	1.0
NZ_CP038449_4	4.2\|189221\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189221-189252	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189221-189252	0	1.0
NZ_CP038449_4	4.2\|189221\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189221-189252	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80509-80540	0	1.0
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189282-189313	0	1.0
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80448-80479	0	1.0
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189343-189374	0	1.0
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80387-80418	0	1.0
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189404-189435	0	1.0
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80326-80357	0	1.0
NZ_CP038449_4	4.6\|189465\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189465-189496	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189465-189496	0	1.0
NZ_CP038449_4	4.6\|189465\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189465-189496	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80265-80296	0	1.0
NZ_CP038449_4	4.7\|189526\|32\|NZ_CP038449\|CRISPRCasFinder,CRT	189526-189557	32	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	189526-189557	0	1.0
NZ_CP038449_4	4.7\|189526\|32\|NZ_CP038449\|CRISPRCasFinder,CRT	189526-189557	32	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	80204-80235	0	1.0
NZ_CP038449_2	2.7\|169747\|33\|NZ_CP038449\|CRISPRCasFinder,CRT	169747-169779	33	DQ839391	Uncultured bacterium plasmid pRSB105, complete sequence	32430-32462	1	0.97
NZ_CP038449_4	4.6\|189465\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189465-189496	32	NZ_CP040718	Aeromonas veronii strain HX3 plasmid pHX3, complete sequence	70894-70925	2	0.938
NZ_CP038449_4	4.6\|189465\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189465-189496	32	NZ_AP019196	Aeromonas caviae strain GSH8M-1 plasmid pGSH8M-1-1, complete sequence	147627-147658	2	0.938
NZ_CP038449_4	4.6\|189465\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189465-189496	32	NZ_CP013966	Aeromonas hydrophila strain D4 plasmid pAhD4-1, complete sequence	138514-138545	2	0.938
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	153427-153478	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	154011-154062	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	154799-154850	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	155383-155434	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	114327-114378	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	114911-114962	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	115699-115750	3	0.942
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	116283-116334	3	0.942
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP016381	Aeromonas hydrophila strain AHNIH1 plasmid pASP-135, complete sequence	33746-33776	4	0.871
NZ_CP038449_3	3.8\|180347\|33\|NZ_CP038449\|CRT	180347-180379	33	NZ_CP016381	Aeromonas hydrophila strain AHNIH1 plasmid pASP-135, complete sequence	33745-33777	5	0.848
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_LR134454	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence	52641-52672	5	0.844
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	76672-76723	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	76958-77009	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	77268-77319	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	77554-77605	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	77864-77915	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038446	Aeromonas media strain R25-3 plasmid pAeme3, complete sequence	78496-78547	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	191214-191265	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	191846-191897	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	192156-192207	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	192442-192493	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	192752-192803	6	0.885
NZ_CP038449_1	1.1\|115336\|52\|NZ_CP038449\|CRISPRCasFinder	115336-115387	52	NZ_CP038449	Aeromonas media strain R50-22 plasmid pAeme5, complete sequence	193038-193089	6	0.885
NZ_CP038449_4	4.2\|189221\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189221-189252	32	NZ_CP015008	Aminobacter aminovorans strain KCTC 2477 plasmid pAA03, complete sequence	126787-126818	6	0.812
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP006370	Aureimonas sp. AU20 plasmid pAU20c, complete sequence	299538-299569	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP047174	Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence	123850-123881	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	302278-302309	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	85035-85066	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	303460-303491	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	302546-302577	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	303702-303733	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	298328-298359	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	298331-298362	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	298331-298362	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	298331-298362	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	298331-298362	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	298331-298362	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP037736	Citrobacter freundii strain CAV1857 plasmid pCAV1857-105, complete sequence	32052-32083	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP017059	Citrobacter freundii strain SL151 plasmid unnamed2, complete sequence	131209-131240	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026241	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-e790, complete sequence	195032-195063	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP029730	Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed2, complete sequence	108805-108836	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP044029	Klebsiella pneumoniae strain RJY9645 plasmid pY9645-166, complete sequence	124788-124819	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP042480	Citrobacter freundii strain C50 plasmid pC50_002, complete sequence	63680-63711	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP042483	Klebsiella pneumoniae strain C51 plasmid pC51_002, complete sequence	31082-31113	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP035277	Citrobacter freundii strain R17 plasmid pCFR17_1, complete sequence	109037-109068	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP048381	Klebsiella variicola strain 118 plasmid p118_B-OXA1, complete sequence	39065-39096	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP042553	Enterobacter hormaechei strain C45 plasmid pC45_002, complete sequence	63680-63711	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP042519	Citrobacter freundii strain E33 plasmid pE33_002, complete sequence	63680-63711	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP011654	Citrobacter freundii strain CAV1741 plasmid pCAV1741-101, complete sequence	77513-77544	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP011610	Citrobacter freundii strain CAV1321 plasmid pCAV1321-135, complete sequence	62641-62672	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	MN699848	Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence	124859-124890	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_MH909344	Enterobacter cloacae strain 12949 plasmid p12949-FIIY, complete sequence	20733-20764	6	0.812
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_MK124610	Citrobacter werkmanii strain Cb_CB1_SE1_NDM_08_2017 plasmid pCB1_SE1_NDM, complete sequence	21682-21713	6	0.812
NZ_CP038449_2	2.6\|169686\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169686-169718	33	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	951349-951381	7	0.788
NZ_CP038449_2	2.6\|169686\|33\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	169686-169718	33	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	956029-956061	7	0.788
NZ_CP038449_3	3.1\|180287\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180287-180317	31	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	109527-109557	7	0.774
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	KU996353	UNVERIFIED: Streptomyces silaceus strain ACCC 40021 plasmid, complete sequence	2229-2259	7	0.774
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP035420	Leisingera sp. NJS204 plasmid unnamed3, complete sequence	31393-31423	7	0.774
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP038235	Leisingera sp. NJS201 plasmid unnamed1, complete sequence	17573-17603	7	0.774
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	MN334766	Serratia phage PCH45, complete genome	189968-189999	7	0.781
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	KY676784	Streptomyces phage ToastyFinz, complete genome	31382-31413	7	0.781
NZ_CP038449_3	3.2\|180348\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180348-180378	31	NZ_CP044217	Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence	227813-227843	8	0.742
NZ_CP038449_3	3.4\|180471\|31\|NZ_CP038449\|CRISPRCasFinder	180471-180501	31	KX397365	Erwinia phage vB_EamM_Caitlin, complete genome	91610-91640	8	0.742
NZ_CP038449_3	3.4\|180471\|31\|NZ_CP038449\|CRISPRCasFinder	180471-180501	31	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	720104-720134	8	0.742
NZ_CP038449_4	4.1\|189160\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189160-189191	32	NZ_CP029776	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed2, complete sequence	119853-119884	8	0.75
NZ_CP038449_4	4.1\|189160\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189160-189191	32	MF140427	Arthrobacter phage Shrooms, complete genome	22332-22363	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	485838-485869	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	1245805-1245836	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	1217881-1217912	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	475348-475379	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	1313352-1313383	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	68823-68854	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	480846-480877	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	472991-473022	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	818978-819009	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	1139900-1139931	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	829883-829914	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	733960-733991	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	934165-934196	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	359838-359869	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	456121-456152	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	1261784-1261815	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	534667-534698	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	624376-624407	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	497618-497649	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	1386177-1386208	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	1158840-1158871	8	0.75
NZ_CP038449_4	4.4\|189343\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189343-189374	32	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	1245811-1245842	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	374840-374871	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	886519-886550	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	AP017627	Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome	1608-1639	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP009292	Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence	259073-259104	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	332707-332738	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	253703-253734	8	0.75
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_016626	Burkholderia sp. YI23 plasmid byi_1p, complete sequence	46044-46075	8	0.75
NZ_CP038449_3	3.7\|180286\|33\|NZ_CP038449\|CRT	180286-180318	33	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	109526-109558	9	0.727
NZ_CP038449_3	3.8\|180347\|33\|NZ_CP038449\|CRT	180347-180379	33	KU996353	UNVERIFIED: Streptomyces silaceus strain ACCC 40021 plasmid, complete sequence	2228-2260	9	0.727
NZ_CP038449_3	3.10\|180470\|33\|NZ_CP038449\|CRT	180470-180502	33	KX397365	Erwinia phage vB_EamM_Caitlin, complete genome	91609-91641	9	0.727
NZ_CP038449_4	4.1\|189160\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189160-189191	32	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	490908-490939	9	0.719
NZ_CP038449_4	4.2\|189221\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189221-189252	32	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	198537-198568	9	0.719
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP049160	Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence	71957-71988	9	0.719
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP022420	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-5, complete sequence	1414-1445	9	0.719
NZ_CP038449_3	3.1\|180287\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180287-180317	31	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	22525-22555	10	0.677
NZ_CP038449_3	3.1\|180287\|31\|NZ_CP038449\|PILER-CR,CRISPRCasFinder	180287-180317	31	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	22471-22501	10	0.677
NZ_CP038449_3	3.6\|180590\|31\|NZ_CP038449\|CRISPRCasFinder	180590-180620	31	NZ_CP045406	Roseovarius sp. THAF9 plasmid pTHAF9_b, complete sequence	46581-46611	10	0.677
NZ_CP038449_4	4.2\|189221\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189221-189252	32	NZ_CP053712	Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence	13310-13341	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP048424	Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence	220117-220148	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NC_022536	Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence	572266-572297	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP039913	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence	254434-254465	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	484273-484304	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP039909	Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence	339514-339545	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1294050-1294081	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1126571-1126602	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	996118-996149	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	800972-801003	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1041109-1041140	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	850783-850814	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1294193-1294224	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1126692-1126723	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1041100-1041131	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	850795-850826	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	790358-790389	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	622952-622983	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1104077-1104108	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1271488-1271519	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1041116-1041147	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	850790-850821	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1293746-1293777	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1126336-1126367	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1293690-1293721	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1126282-1126313	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	969698-969729	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	859249-859280	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	782085-782116	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	614925-614956	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	927461-927492	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	822499-822530	10	0.688
NZ_CP038449_4	4.5\|189404\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189404-189435	32	NC_014718	Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence	592187-592218	10	0.688
NZ_CP038449_4	4.3\|189282\|32\|NZ_CP038449\|PILER-CR,CRISPRCasFinder,CRT	189282-189313	32	NZ_CP018001	Rhizobium sp. Y9 plasmid pY9, complete sequence	469746-469777	11	0.656

1. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	Protospacer
****************************************************

2. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	Protospacer
****************************************************

3. spacer 2.1|169380|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

catcagggcatgtccggccccgcgttttcccgt	CRISPR spacer
catcagggcatgtccggccccgcgttttcccgt	Protospacer
*********************************

4. spacer 2.1|169380|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

catcagggcatgtccggccccgcgttttcccgt	CRISPR spacer
catcagggcatgtccggccccgcgttttcccgt	Protospacer
*********************************

5. spacer 2.2|169441|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

taacggatgattttccgcagttggcgtagaacc	CRISPR spacer
taacggatgattttccgcagttggcgtagaacc	Protospacer
*********************************

6. spacer 2.2|169441|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

taacggatgattttccgcagttggcgtagaacc	CRISPR spacer
taacggatgattttccgcagttggcgtagaacc	Protospacer
*********************************

7. spacer 2.3|169502|34|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

atctgctgtttgatccattttttgactcctgtaa	CRISPR spacer
atctgctgtttgatccattttttgactcctgtaa	Protospacer
**********************************

8. spacer 2.3|169502|34|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

atctgctgtttgatccattttttgactcctgtaa	CRISPR spacer
atctgctgtttgatccattttttgactcctgtaa	Protospacer
**********************************

9. spacer 2.4|169564|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ggatacgccggagctgatggccgggctgtagat	CRISPR spacer
ggatacgccggagctgatggccgggctgtagat	Protospacer
*********************************

10. spacer 2.4|169564|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ggatacgccggagctgatggccgggctgtagat	CRISPR spacer
ggatacgccggagctgatggccgggctgtagat	Protospacer
*********************************

11. spacer 2.5|169625|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ggctaatgctcaatggaagtttttcttggaatc	CRISPR spacer
ggctaatgctcaatggaagtttttcttggaatc	Protospacer
*********************************

12. spacer 2.5|169625|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ggctaatgctcaatggaagtttttcttggaatc	CRISPR spacer
ggctaatgctcaatggaagtttttcttggaatc	Protospacer
*********************************

13. spacer 2.6|169686|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gggctccgaggcccgcgaggagcaaaagcgtct	CRISPR spacer
gggctccgaggcccgcgaggagcaaaagcgtct	Protospacer
*********************************

14. spacer 2.6|169686|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gggctccgaggcccgcgaggagcaaaagcgtct	CRISPR spacer
gggctccgaggcccgcgaggagcaaaagcgtct	Protospacer
*********************************

15. spacer 2.7|169747|33|NZ_CP038449|CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

cgcctggctatgcaggccagcaagctggccgcc	CRISPR spacer
cgcctggctatgcaggccagcaagctggccgcc	Protospacer
*********************************

16. spacer 2.7|169747|33|NZ_CP038449|CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

cgcctggctatgcaggccagcaagctggccgcc	CRISPR spacer
cgcctggctatgcaggccagcaagctggccgcc	Protospacer
*********************************

17. spacer 3.1|180287|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

cctacggcggggaaaccagcgagctggtcga	CRISPR spacer
cctacggcggggaaaccagcgagctggtcga	Protospacer
*******************************

18. spacer 3.1|180287|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

cctacggcggggaaaccagcgagctggtcga	CRISPR spacer
cctacggcggggaaaccagcgagctggtcga	Protospacer
*******************************

19. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
gcggccagttcggcagccagggaaggatcgc	Protospacer
*******************************

20. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
gcggccagttcggcagccagggaaggatcgc	Protospacer
*******************************

21. spacer 3.3|180409|32|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

agttgctggattgtttcgagttggtcgttata	CRISPR spacer
agttgctggattgtttcgagttggtcgttata	Protospacer
********************************

22. spacer 3.3|180409|32|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

agttgctggattgtttcgagttggtcgttata	CRISPR spacer
agttgctggattgtttcgagttggtcgttata	Protospacer
********************************

23. spacer 3.4|180471|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgaccgccgcacagcgagctgcccccg	CRISPR spacer
gcgctgaccgccgcacagcgagctgcccccg	Protospacer
*******************************

24. spacer 3.4|180471|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgaccgccgcacagcgagctgcccccg	CRISPR spacer
gcgctgaccgccgcacagcgagctgcccccg	Protospacer
*******************************

25. spacer 3.5|180532|28|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

atctcccacccaattctcaccgtgataa	CRISPR spacer
atctcccacccaattctcaccgtgataa	Protospacer
****************************

26. spacer 3.5|180532|28|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

atctcccacccaattctcaccgtgataa	CRISPR spacer
atctcccacccaattctcaccgtgataa	Protospacer
****************************

27. spacer 3.6|180590|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ctattttggtcaccgttaccaaaaaggattc	CRISPR spacer
ctattttggtcaccgttaccaaaaaggattc	Protospacer
*******************************

28. spacer 3.6|180590|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ctattttggtcaccgttaccaaaaaggattc	CRISPR spacer
ctattttggtcaccgttaccaaaaaggattc	Protospacer
*******************************

29. spacer 3.7|180286|33|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gcctacggcggggaaaccagcgagctggtcgag	CRISPR spacer
gcctacggcggggaaaccagcgagctggtcgag	Protospacer
*********************************

30. spacer 3.7|180286|33|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gcctacggcggggaaaccagcgagctggtcgag	CRISPR spacer
gcctacggcggggaaaccagcgagctggtcgag	Protospacer
*********************************

31. spacer 3.8|180347|33|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ggcggccagttcggcagccagggaaggatcgcg	CRISPR spacer
ggcggccagttcggcagccagggaaggatcgcg	Protospacer
*********************************

32. spacer 3.8|180347|33|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ggcggccagttcggcagccagggaaggatcgcg	CRISPR spacer
ggcggccagttcggcagccagggaaggatcgcg	Protospacer
*********************************

33. spacer 3.9|180408|34|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gagttgctggattgtttcgagttggtcgttatag	CRISPR spacer
gagttgctggattgtttcgagttggtcgttatag	Protospacer
**********************************

34. spacer 3.9|180408|34|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gagttgctggattgtttcgagttggtcgttatag	CRISPR spacer
gagttgctggattgtttcgagttggtcgttatag	Protospacer
**********************************

35. spacer 3.10|180470|33|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ggcgctgaccgccgcacagcgagctgcccccgc	CRISPR spacer
ggcgctgaccgccgcacagcgagctgcccccgc	Protospacer
*********************************

36. spacer 3.10|180470|33|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ggcgctgaccgccgcacagcgagctgcccccgc	CRISPR spacer
ggcgctgaccgccgcacagcgagctgcccccgc	Protospacer
*********************************

37. spacer 3.11|180531|30|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

gatctcccacccaattctcaccgtgataaa	CRISPR spacer
gatctcccacccaattctcaccgtgataaa	Protospacer
******************************

38. spacer 3.11|180531|30|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

gatctcccacccaattctcaccgtgataaa	CRISPR spacer
gatctcccacccaattctcaccgtgataaa	Protospacer
******************************

39. spacer 3.12|180589|33|NZ_CP038449|CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

tctattttggtcaccgttaccaaaaaggattcc	CRISPR spacer
tctattttggtcaccgttaccaaaaaggattcc	Protospacer
*********************************

40. spacer 3.12|180589|33|NZ_CP038449|CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

tctattttggtcaccgttaccaaaaaggattcc	CRISPR spacer
tctattttggtcaccgttaccaaaaaggattcc	Protospacer
*********************************

41. spacer 4.1|189160|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ggcacgcgccgcgccctgacccacctgcgggc	CRISPR spacer
ggcacgcgccgcgccctgacccacctgcgggc	Protospacer
********************************

42. spacer 4.1|189160|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ggcacgcgccgcgccctgacccacctgcgggc	CRISPR spacer
ggcacgcgccgcgccctgacccacctgcgggc	Protospacer
********************************

43. spacer 4.2|189221|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

cccgccgacgaggagatcgcgacattcctcca	CRISPR spacer
cccgccgacgaggagatcgcgacattcctcca	Protospacer
********************************

44. spacer 4.2|189221|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

cccgccgacgaggagatcgcgacattcctcca	CRISPR spacer
cccgccgacgaggagatcgcgacattcctcca	Protospacer
********************************

45. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
acggcaccggcatcgatgcgcgactcggcggt	Protospacer
********************************

46. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
acggcaccggcatcgatgcgcgactcggcggt	Protospacer
********************************

47. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ccatcggactcgaccgcatcggaggcgcccac	CRISPR spacer
ccatcggactcgaccgcatcggaggcgcccac	Protospacer
********************************

48. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ccatcggactcgaccgcatcggaggcgcccac	CRISPR spacer
ccatcggactcgaccgcatcggaggcgcccac	Protospacer
********************************

49. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cccaagacgatcgcgcccacgcccacgacggc	Protospacer
********************************

50. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cccaagacgatcgcgcccacgcccacgacggc	Protospacer
********************************

51. spacer 4.6|189465|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

taccagctcaagatcagagggctttccttggc	CRISPR spacer
taccagctcaagatcagagggctttccttggc	Protospacer
********************************

52. spacer 4.6|189465|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

taccagctcaagatcagagggctttccttggc	CRISPR spacer
taccagctcaagatcagagggctttccttggc	Protospacer
********************************

53. spacer 4.7|189526|32|NZ_CP038449|CRISPRCasFinder,CRT matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 0, identity: 1.0

ttcaacccggcatgtgaacgccataagctgac	CRISPR spacer
ttcaacccggcatgtgaacgccataagctgac	Protospacer
********************************

54. spacer 4.7|189526|32|NZ_CP038449|CRISPRCasFinder,CRT matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 0, identity: 1.0

ttcaacccggcatgtgaacgccataagctgac	CRISPR spacer
ttcaacccggcatgtgaacgccataagctgac	Protospacer
********************************

55. spacer 2.7|169747|33|NZ_CP038449|CRISPRCasFinder,CRT matches to DQ839391 (Uncultured bacterium plasmid pRSB105, complete sequence) position: , mismatch: 1, identity: 0.97

cgcctggctatgcaggccagcaagctggccgcc	CRISPR spacer
tgcctggctatgcaggccagcaagctggccgcc	Protospacer
.********************************

56. spacer 4.6|189465|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040718 (Aeromonas veronii strain HX3 plasmid pHX3, complete sequence) position: , mismatch: 2, identity: 0.938

taccagctcaagatcagagggctttccttggc	CRISPR spacer
taccaactcaagatcagagggctctccttggc	Protospacer
*****.*****************.********

57. spacer 4.6|189465|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019196 (Aeromonas caviae strain GSH8M-1 plasmid pGSH8M-1-1, complete sequence) position: , mismatch: 2, identity: 0.938

taccagctcaagatcagagggctttccttggc	CRISPR spacer
taccaactcaagattagagggctttccttggc	Protospacer
*****.********.*****************

58. spacer 4.6|189465|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013966 (Aeromonas hydrophila strain D4 plasmid pAhD4-1, complete sequence) position: , mismatch: 2, identity: 0.938

taccagctcaagatcagagggctttccttggc	CRISPR spacer
taccaactcaagatcagagggctctccttggc	Protospacer
*****.*****************.********

59. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

60. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

61. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

62. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

63. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

64. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

65. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

66. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 3, identity: 0.942

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcagggccccgg	Protospacer
************************************************. *.

67. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP016381 (Aeromonas hydrophila strain AHNIH1 plasmid pASP-135, complete sequence) position: , mismatch: 4, identity: 0.871

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
tcggccagttcagcagccagagaaggatctc	Protospacer
 **********.********.******** *

68. spacer 3.8|180347|33|NZ_CP038449|CRT matches to NZ_CP016381 (Aeromonas hydrophila strain AHNIH1 plasmid pASP-135, complete sequence) position: , mismatch: 5, identity: 0.848

ggcggccagttcggcagccagggaaggatcgcg	CRISPR spacer
gtcggccagttcagcagccagagaaggatctct	Protospacer
* **********.********.******** *

69. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134454 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 12, complete sequence) position: , mismatch: 5, identity: 0.844

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
ccgccgacgatcgcgcccgcgccctcgacggc	Protospacer
**   *************.***** *******

70. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

71. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

72. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

73. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

74. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

75. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038446 (Aeromonas media strain R25-3 plasmid pAeme3, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

76. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

77. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

78. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

79. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

80. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

81. spacer 1.1|115336|52|NZ_CP038449|CRISPRCasFinder matches to NZ_CP038449 (Aeromonas media strain R50-22 plasmid pAeme5, complete sequence) position: , mismatch: 6, identity: 0.885

ttctgattggttcggcgtccggcggtggccggtacctgcggcagggcctgga	CRISPR spacer
ttctgattggttcggcgtccggcggtggccggtacctgcggcggacccagct	Protospacer
******************************************.*. ** *

82. spacer 4.2|189221|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015008 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA03, complete sequence) position: , mismatch: 6, identity: 0.812

cccgccgacgaggagatcgcgacattcctcca	CRISPR spacer
gccgccgacgaggtgatcgcggcattcggcaa	Protospacer
 ************ *******.*****  * *

83. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006370 (Aureimonas sp. AU20 plasmid pAU20c, complete sequence) position: , mismatch: 6, identity: 0.812

acggcaccg-gcatcgatgcgcgactcggcggt	CRISPR spacer
-aggctctgcgcctcgatgcgccactcggcggt	Protospacer
  *** *.* ** ********* **********

84. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047174 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
agcaccacgatcgcgcgcccgcccacgacggc	Protospacer
  **  ********** * *************

85. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

86. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

87. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

88. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

89. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

90. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

91. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

92. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

93. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

94. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

95. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccgcgccgatcccgcccacgcccacgccggc	Protospacer
 **. * ***** ************** ****

96. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037736 (Citrobacter freundii strain CAV1857 plasmid pCAV1857-105, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

97. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017059 (Citrobacter freundii strain SL151 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

98. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026241 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-e790, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

99. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029730 (Citrobacter sp. CRE-46 strain AR_0157 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

100. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP044029 (Klebsiella pneumoniae strain RJY9645 plasmid pY9645-166, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

101. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042480 (Citrobacter freundii strain C50 plasmid pC50_002, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

102. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042483 (Klebsiella pneumoniae strain C51 plasmid pC51_002, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

103. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035277 (Citrobacter freundii strain R17 plasmid pCFR17_1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

104. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048381 (Klebsiella variicola strain 118 plasmid p118_B-OXA1, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

105. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042553 (Enterobacter hormaechei strain C45 plasmid pC45_002, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

106. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042519 (Citrobacter freundii strain E33 plasmid pE33_002, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

107. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011654 (Citrobacter freundii strain CAV1741 plasmid pCAV1741-101, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

108. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011610 (Citrobacter freundii strain CAV1321 plasmid pCAV1321-135, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

109. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to MN699848 (Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

110. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH909344 (Enterobacter cloacae strain 12949 plasmid p12949-FIIY, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

111. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK124610 (Citrobacter werkmanii strain Cb_CB1_SE1_NDM_08_2017 plasmid pCB1_SE1_NDM, complete sequence) position: , mismatch: 6, identity: 0.812

cccaagac----gatcgcgcccacgcccacgacggc	CRISPR spacer
----agaccgcagagcgcgcccacgcccacgccggc	Protospacer
    ****    ** **************** ****

112. spacer 2.6|169686|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 7, identity: 0.788

gggctccgaggcccgcgaggagcaaaagcgtct	CRISPR spacer
gtacgccgaggcccgcgaggagcgaacgcgcca	Protospacer
* .* ******************.** ***.*

113. spacer 2.6|169686|33|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 7, identity: 0.788

gggctccgaggcccgcgaggagcaaaagcgtct	CRISPR spacer
gtacgccgaggcccgcgaggagcgaacgcgcca	Protospacer
* .* ******************.** ***.*

114. spacer 3.1|180287|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 7, identity: 0.774

cctacggcggggaaaccagcgagctggtcga	CRISPR spacer
cctacggcgcggaaaccagcgtgctcggttt	Protospacer
********* *********** *** * .

115. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to KU996353 (UNVERIFIED: Streptomyces silaceus strain ACCC 40021 plasmid, complete sequence) position: , mismatch: 7, identity: 0.774

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
cgggccagttcggcggccagggacggcccgt	Protospacer
  ************.******** ** .**.

116. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP035420 (Leisingera sp. NJS204 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.774

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
gcgcccatttcggcagccagggatcaaaagc	Protospacer
*** *** ***************  .*  **

117. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP038235 (Leisingera sp. NJS201 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.774

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
gcgcccatttcggcagccagggatcaaaggc	Protospacer
*** *** ***************  .*  **

118. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to MN334766 (Serratia phage PCH45, complete genome) position: , mismatch: 7, identity: 0.781

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
accgccacgatcgcgaccacggccacgacgga	Protospacer
 **.  ********* ***** *********

119. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to KY676784 (Streptomyces phage ToastyFinz, complete genome) position: , mismatch: 7, identity: 0.781

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cccgcctcgaccgcgcccacgcccaccacgcc	Protospacer
***.   ***.*************** *** *

120. spacer 3.2|180348|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP044217 (Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

gcggccagttcggcagccagggaaggatcgc	CRISPR spacer
ccggggagttcggcagccagggaaccaggac	Protospacer
 ***  ******************  *  .*

121. spacer 3.4|180471|31|NZ_CP038449|CRISPRCasFinder matches to KX397365 (Erwinia phage vB_EamM_Caitlin, complete genome) position: , mismatch: 8, identity: 0.742

gcgctgaccgccgcacagcgagctgcccccg	CRISPR spacer
aaatacaccgccgcactgcgagctgccccca	Protospacer
. ..  ********** *************.

122. spacer 3.4|180471|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.742

gcgctgaccgccgcacagcgagctgcccccg	CRISPR spacer
ccgctgaccgccgctcagcgcgcttatctgg	Protospacer
 ************* ***** ***  .*. *

123. spacer 4.1|189160|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029776 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ggcacgcgccgcgccctgacccacctgcgggc	CRISPR spacer
ggcacccgccgcgccctgacgcaggacccggt	Protospacer
***** ************** **    * **.

124. spacer 4.1|189160|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to MF140427 (Arthrobacter phage Shrooms, complete genome) position: , mismatch: 8, identity: 0.75

ggcacgcgccgcgccctgacccacctgcgggc	CRISPR spacer
gcccgccgccgcgccctcacccaccttcgccc	Protospacer
* *   *********** ******** **  *

125. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

126. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

127. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

128. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

129. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

130. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

131. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

132. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

133. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

134. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

135. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

136. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

137. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

138. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

139. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

140. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

141. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

142. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

143. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

144. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

145. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

146. spacer 4.4|189343|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 8, identity: 0.75

ccatcgg--actcgaccgcatcggaggcgcccac	CRISPR spacer
--gccggctgctcgaccgcatcggcggcgaccag	Protospacer
  ..***  .************** **** ***

147. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gcgccgacgatcgcgcccacgaccaccacgcg	Protospacer
 *   **************** **** ***

148. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cacctcgcgatcgcgcccgcgcccacgccggt	Protospacer
* *   .***********.******** ***.

149. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to AP017627 (Pleomorphomonas sp. SM30 plasmid pSM30-1 DNA, complete genome) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cggcgctcgatcgcgccttcgcccacgacggc	Protospacer
*   .  **********. *************

150. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009292 (Novosphingobium pentaromativorans US6-1 plasmid pLA3, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
agcgcgccaatcgcgcccaggcccaggacggc	Protospacer
  *. * *.********** ***** ******

151. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
cccatcacgatcgcgcccacgccggccatgta	Protospacer
****  ***************** .* *.*

152. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
ccgacgacgatcgcgcccacgccgaacagcac	Protospacer
** * ****************** *  *  .*

153. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_016626 (Burkholderia sp. YI23 plasmid byi_1p, complete sequence) position: , mismatch: 8, identity: 0.75

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
ccgacgacgatcgcgcccacgccgaacagcac	Protospacer
** * ****************** *  *  .*

154. spacer 3.7|180286|33|NZ_CP038449|CRT matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 9, identity: 0.727

gcctacggcggggaaaccagcgagctggtcgag	CRISPR spacer
ccctacggcgcggaaaccagcgtgctcggtttc	Protospacer
 ********* *********** *** * .

155. spacer 3.8|180347|33|NZ_CP038449|CRT matches to KU996353 (UNVERIFIED: Streptomyces silaceus strain ACCC 40021 plasmid, complete sequence) position: , mismatch: 9, identity: 0.727

ggcggccagttcggcagccagggaaggatcgcg	CRISPR spacer
tcgggccagttcggcggccagggacggcccgtc	Protospacer
   ************.******** ** .**.

156. spacer 3.10|180470|33|NZ_CP038449|CRT matches to KX397365 (Erwinia phage vB_EamM_Caitlin, complete genome) position: , mismatch: 9, identity: 0.727

ggcgctgaccgccgcacagcgagctgcccccgc	CRISPR spacer
aaaatacaccgccgcactgcgagctgcccccac	Protospacer
.. ..  ********** *************.*

157. spacer 4.1|189160|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 9, identity: 0.719

ggcacgcgccgcgccctgacccacctgcgggc	CRISPR spacer
ctcgcctcccgcccgctgacccacctgcggga	Protospacer
  *.* . **** * ****************

158. spacer 4.2|189221|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 9, identity: 0.719

cccgccgacgaggagatcgcgacattcctcca	CRISPR spacer
cccgcggacgaggagatcgccacggtcacggc	Protospacer
***** ************** **. ** .

159. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049160 (Caballeronia sp. SBC1 plasmid pSBC1_4, complete sequence) position: , mismatch: 9, identity: 0.719

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gtgctgcacgcatcgctgctcgactcggcggt	Protospacer
..* ..*  ****** *** ************

160. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022420 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-5, complete sequence) position: , mismatch: 9, identity: 0.719

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
tggatcccggcatggatacgcgactcggcatt	Protospacer
  *.. ******* ***.***********. *

161. spacer 3.1|180287|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 10, identity: 0.677

cctacggcggggaaaccagcgagctggtcga	CRISPR spacer
gtattttcgaggaaaccggcgagctggtcgg	Protospacer
 .  .  **.*******.************.

162. spacer 3.1|180287|31|NZ_CP038449|PILER-CR,CRISPRCasFinder matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 10, identity: 0.677

cctacggcggggaaaccagcgagctggtcga	CRISPR spacer
gtattttcgaggaaaccggcgagctggtcgg	Protospacer
 .  .  **.*******.************.

163. spacer 3.6|180590|31|NZ_CP038449|CRISPRCasFinder matches to NZ_CP045406 (Roseovarius sp. THAF9 plasmid pTHAF9_b, complete sequence) position: , mismatch: 10, identity: 0.677

ctattttggtcaccgttaccaaaaaggattc	CRISPR spacer
accgccgggtcaccgtcaccaaaaaggtttg	Protospacer
 .  .. *********.********** **

164. spacer 4.2|189221|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053712 (Acetobacteraceae bacterium strain PAMC 26569 plasmid unnamed5, complete sequence) position: , mismatch: 10, identity: 0.688

cccgccgacgaggagatcgcgacattcctcca	CRISPR spacer
gtttccgacgaggagatggcgacactcaacat	Protospacer
 .. ************* ******.**  *

165. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048424 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgacacggccta	Protospacer
. .  .****************** ****

166. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_022536 (Rhizobium sp. IRBG74 plasmid IRBL74_p, complete sequence) position: , mismatch: 10, identity: 0.688

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgatacggcgca	Protospacer
. .  .*****************. *****

167. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039913 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625b, complete sequence) position: , mismatch: 10, identity: 0.688

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgatacggcgca	Protospacer
. .  .*****************. *****

168. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 10, identity: 0.688

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgatacggcgca	Protospacer
. .  .*****************. *****

169. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039909 (Agrobacterium tumefaciens strain CFBP6624 plasmid pAtCFBP6624, complete sequence) position: , mismatch: 10, identity: 0.688

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgatacggcgca	Protospacer
. .  .*****************. *****

170. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

171. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

172. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

173. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

174. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

175. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

176. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

177. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

178. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

179. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

180. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

181. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

182. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

183. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

184. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

185. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

186. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

187. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

188. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

189. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

190. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

191. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

192. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

193. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

194. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
aggtggacgatcgcgtccacgccctcgaccag	Protospacer
    .**********.******** **** .

195. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
gccaaggcgatcgcgctcacgcccgaagtgcg	Protospacer
 *****.*********.*******. ...*

196. spacer 4.5|189404|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NC_014718 (Paraburkholderia rhizoxinica HKI 454 plasmid pBRH01, complete sequence) position: , mismatch: 10, identity: 0.688

cccaagacgatcgcgcccacgcccacgacggc	CRISPR spacer
ggatcgacgatcgcgcgcacgcacacgaaagg	Protospacer
     *********** ***** ***** .*

197. spacer 4.3|189282|32|NZ_CP038449|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018001 (Rhizobium sp. Y9 plasmid pY9, complete sequence) position: , mismatch: 11, identity: 0.656

acggcaccggcatcgatgcgcgactcggcggt	CRISPR spacer
gaatggccggcatcgatgcgcgatacggccta	Protospacer
. .  .*****************. ****

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP038450

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP038448

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NZ_CP038449

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection