CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053764	Bacillus velezensis strain B268 chromosome, complete genome	1 crisprs	csa3,DinG,casR,cas3,DEDDh	0	1	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053764_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053764_1

2911306-2911411

Orphan

Consensus_repeat	Method
TGATGGGAATCGAACCCACGACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053764_1

>merge|NZ_CP053764|1|2911306-2911411|CRISPRCasFinder
TGATGGGAATCGAACCCACGACATCAGCTTGGAAGGCTGAGGTTTTACCACTAAACTACACCCGCATGTTGTTTGGGGCGATTGATGGGAATCGAACCCACGAATG

>NZ_CP053764|1|1|2911306-2911411|CRISPRCasFinder
TGATGGGAATCGAACCCACGACAT	CAGCTTGGAAGGCTGAGGTTTTACCACTAAACTACACCCGCATGTTGTTTGGGGCGAT
TGATGGGAATCGAACCCACGAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053764.1\|WP_172614921.1\|2901785_2902901_-\|o-succinylbenzoate-synthase	unknown	unknown	gnl\|CDD\|239433
NZ_CP053764.1\|WP_003152221.1\|2904448_2905267_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl\|CDD\|180958
NZ_CP053764.1\|WP_070082729.1\|2925917_2926457_+\|DUF1016-domain-containing-protein	unknown	unknown	gnl\|CDD\|379999
NZ_CP053764.1\|WP_003152182.1\|2921651_2922233_-\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377051
NZ_CP053764.1\|WP_146284167.1\|2918324_2918906_+\|energy-coupled-thiamine-transporter-ThiT	unknown	unknown	gnl\|CDD\|226377
NZ_CP053764.1\|WP_003152224.1\|2901239_2901398_+\|DUF1540-domain-containing-protein	unknown	unknown	gnl\|CDD\|377869
NZ_CP053764.1\|WP_017418423.1\|2900141_2901182_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224213
NZ_CP053764.1\|WP_172614923.1\|2905325_2906150_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|274729
NZ_CP053764.1\|WP_003152213.1\|2909568_2910288_+\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|274340
NZ_CP053764.1\|WP_077722739.1\|2910443_2910914_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|226007
NZ_CP053764.1\|WP_003152179.1\|2925202_2925757_+\|GbsR/MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224427
NZ_CP053764.1\|WP_077722737.1\|2906137_2907874_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl\|CDD\|236020
NZ_CP053764.1\|WP_070082256.1\|2921161_2921650_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NZ_CP053764.1\|WP_003152180.1\|2923529_2925002_-\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143437
NZ_CP053764.1\|WP_003152181.1\|2922304_2923513_-\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|341481
NZ_CP053764.1\|WP_070082252.1\|2907870_2909286_-\|isochorismate-synthase-MenF	unknown	unknown	gnl\|CDD\|224091
NZ_CP053764.1\|WP_058906302.1\|2926620_2927289_+\|TrkA-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|223643
NZ_CP053764.1\|WP_172614922.1\|2902897_2904361_-\|o-succinylbenzoate--CoA-ligase	unknown	unknown	gnl\|CDD\|235146
NZ_CP053764.1\|WP_032876878.1\|2920485_2921016_-\|NfeD-family-protein	unknown	unknown	gnl\|CDD\|376684
NZ_CP053764.1\|WP_024085720.1\|2918936_2920466_-\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|225177

Protein	Function_ID	Function_description	E-value
NZ_CP053764.1\|WP_172614921.1\|2901785_2902901_-\|o-succinylbenzoate-synthase	gnl\|CDD\|239433	cd03317, NAAAR, N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NZ_CP053764.1\|WP_003152221.1\|2904448_2905267_-\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl\|CDD\|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
NZ_CP053764.1\|WP_070082729.1\|2925917_2926457_+\|DUF1016-domain-containing-protein	gnl\|CDD\|379999	pfam17735, BslA, Biofilm surface layer A. This family includes members such as BslA (previously called YuaB). Secreted BslA from Bacillus subtillis has been shown to form surface layers around the biofilm self-assembling at interfaces of B. subtilis biofilms, forming an elastic film. structural analysis revealed that BslA consists of an Ig-type fold with the addition of an unusual, extremely hydrophobic cap region. The hydrophobic cap exhibits physiochemical properties similar to the hydrophobic surface found in fungal hydrophobins; thus, BslA is defined as member of a class of bacterially produced hydrophobins.	6.16076e-47
NZ_CP053764.1\|WP_003152182.1\|2921651_2922233_-\|MOSC-domain-containing-protein	gnl\|CDD\|377051	pfam03473, MOSC, MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine, and delivers it for the formation of diverse sulfur-metal clusters.	9.31518e-08
NZ_CP053764.1\|WP_146284167.1\|2918324_2918906_+\|energy-coupled-thiamine-transporter-ThiT	gnl\|CDD\|226377	COG3859, COG3859, Predicted membrane protein [Function unknown].	5.28492e-64
NZ_CP053764.1\|WP_003152224.1\|2901239_2901398_+\|DUF1540-domain-containing-protein	gnl\|CDD\|377869	pfam07561, DUF1540, Domain of Unknown Function (DUF1540). This family has four conserved cysteines, which is suggestive of a metal binding function.	1.79299e-11
NZ_CP053764.1\|WP_017418423.1\|2900141_2901182_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|224213	COG1294, AppB, Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion].	1.10739e-69
NZ_CP053764.1\|WP_172614923.1\|2905325_2906150_-\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.7563e-117
NZ_CP053764.1\|WP_003152213.1\|2909568_2910288_+\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	1.61161e-59
NZ_CP053764.1\|WP_077722739.1\|2910443_2910914_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|226007	COG3476, COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) [Signal transduction mechanisms].	4.15907e-35
NZ_CP053764.1\|WP_003152179.1\|2925202_2925757_+\|GbsR/MarR-family-transcriptional-regulator	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	6.06498e-68
NZ_CP053764.1\|WP_077722737.1\|2906137_2907874_-\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl\|CDD\|236020	PRK07449, PRK07449, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Validated.	0
NZ_CP053764.1\|WP_070082256.1\|2921161_2921650_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	1.05241e-18
NZ_CP053764.1\|WP_003152180.1\|2923529_2925002_-\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|143437	cd07119, ALDH_BADH-GbsA, Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like. Included in this CD is the NAD+-dependent, betaine aldehyde dehydrogenase (BADH, GbsA, EC=1.2.1.8) of Bacillus subtilis involved in the synthesis of the osmoprotectant glycine betaine from choline or glycine betaine aldehyde.	0
NZ_CP053764.1\|WP_003152181.1\|2922304_2923513_-\|choline-dehydrogenase	gnl\|CDD\|341481	cd08551, Fe-ADH, iron-containing alcohol dehydrogenases (Fe-ADH)-like. This family contains large metal-containing alcohol dehydrogenases (ADH), known as iron-containing alcohol dehydrogenases. They contain a dehydroquinate synthase-like protein structural fold and mostly contain iron. They are distinct from other alcohol dehydrogenases which contains different protein domains. There are several distinct families of alcohol dehydrogenases: Zinc-containing long-chain alcohol dehydrogenases, insect-type, or short-chain alcohol dehydrogenases, iron-containing alcohol dehydrogenases, among others. The iron-containing family has a Rossmann fold-like topology that resembles the fold of the zinc-dependent alcohol dehydrogenases, but lacks sequence homology, and differs in strand arrangement. ADH catalyzes the reversible oxidation of alcohol to acetaldehyde with the simultaneous reduction of NAD(P)+ to NAD(P)H.	1.71856e-172
NZ_CP053764.1\|WP_070082252.1\|2907870_2909286_-\|isochorismate-synthase-MenF	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.67264e-143
NZ_CP053764.1\|WP_058906302.1\|2926620_2927289_+\|TrkA-family-potassium-uptake-protein	gnl\|CDD\|223643	COG0569, TrkA, K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism].	3.88826e-68
NZ_CP053764.1\|WP_172614922.1\|2902897_2904361_-\|o-succinylbenzoate--CoA-ligase	gnl\|CDD\|235146	PRK03640, PRK03640, o-succinylbenzoate--CoA ligase.	0
NZ_CP053764.1\|WP_032876878.1\|2920485_2921016_-\|NfeD-family-protein	gnl\|CDD\|376684	pfam01957, NfeD, NfeD-like C-terminal, partner-binding. NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There appear to be three major groups: an ancestral group with only an N-terminal serine protease domain and this C-terminal beta sheet-rich domain which is structurally very similar to the OB-fold domain, associated with its neighboring slipin cluster; a second major group with an additional middle, membrane-spanning domain, associated in some species with eoslipin and in others with yqfA; a final 'artificial' group which unites truncated forms lacking the protease region and associated with their ancestral gene partner, either yqfA or eoslipin. This NefD, C-terminal, domain appears to be the major one for relating to the associated protein. NfeD homologs are clearly reliant on their conserved gene neighbor which is assumed to be necessary for function, either through direct physical interaction or by functioning in the same pathway, possibly involve with lipid-rafts.	2.0504e-05
NZ_CP053764.1\|WP_024085720.1\|2918936_2920466_-\|flotillin-family-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	1.53136e-120

>NZ_CP053764.1|WP_077722739.1|2910443_2910914_+|tryptophan-rich-sensory-protein
MKKKYIGAIIVFIITYVLFSLAGFLFPIDREWYDALQKPDWTPSGSVIGIIWAVLFALISLSAALIYARFSCKESKAFWVMLLINYIVNQGFSYFQFTQKNLLAASIDCLLVAVTTLILLLIAGKYSKASAWLLVPYLLWSAFATYLSFTIYAMNA
>NZ_CP053764.1|WP_003152213.1|2909568_2910288_+|TraR/DksA-C4-type-zinc-finger-protein
MLTNEQITHLKKELEEARDDILSRFKENDQFQLTDEFPYQSSGELSSYDNHPGDQATELYEREKDLALLDHEREHLRDIDYSLKQIENGTYGTCEVSGKDIPYDRLEALPTATTLAEYSSQDAVSKDRPIEEETPFGQFEFDDDESIRAAYDSEDAYQDVEEYGNSETPQDLEDPPLSYGDMTMNSEENIGYAEDYENFIATDITGKNISVYPSKAHEKYEQELDEEGIMTTFGDLHAD
>NZ_CP053764.1|WP_070082252.1|2907870_2909286_-|isochorismate-synthase-MenF
MVTTVQHTFREEADHALHKAKQVNHAVLLSYSRRIASLDPLSFFKDGAKKYKGKRFFWSEPGSELTIVGLGTEALFQSNEKNGKRYHDVFEQWERFKKTAFHIHEEEEAAHTAVGPVLFGGFSFNPAEERGDEWNGFEEGLFFIPSLMLTKTADGDYLTVNQWAADGNQAEDTLKRLKSFSEAFAVSSIQYEEYPVLTKAEELDVENWLEAIKTATNDMKANQYDKVVLAREVVLSYDGPIPAESVVRKLLTDQTTSYVFAIEQGDKCFVGASPERLIKKSGKDVMSTCLAGSIKRGENQQEDDRLGKELLHDEKNLAEHDFVVQMIHDSFLASCSDVKKPAGPQLYKTKSVQHLYTPITGHLKTSASLFDLIEKLHPTPALGGAPQQKAVEVIADIEPMTRGWYAAPIGWMDGRENGEFVVAIRSGLIEGKSARLFAGCGIVEDSDPQSEYEETQIKLKPMISALGGERL
>NZ_CP053764.1|WP_077722737.1|2906137_2907874_-|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MTNPITHYIGSFIDEFALSGVTDAVVCPGSRSTPLAVLAAAHPDIQVHIQIDERSAGFFALGLAKARQRPVMLICTSGTAAANFYPAVIEAHYSRVPLIVLTADRPHELREVGAPQAINQHFLFGNFVKFFTDSALPEENPQMLSYIRTLAGRAVSEAGKRPMGPVHINVPLREPLMPDLSAGPFERMRKGKHVSVTTGMQSADQDALCHITERLAGTERGMIVCGEIHGEAEKQQIIALAEMLQFPILADPLSNLRNGEHDKTLIIDAYDSFLKDEEIKEALRPDAVIRFGPMPVSKPLFLWLRDDPAIEQFIVDEDGGWRDPTQAGAHMIHCHPSVFLEAVRSAETGKRPSGWLEKWQFVNARFRSHLQAASMDDLSFEGNVYRQLQHLVPEGSSIFVGNSMPIRDVDTFFEKQDRSFRVYANRGANGIDGVVSSAMGLCEGTKAPVTLVIGDLSFYHDLNGLLAAKKLGIPLTVILINNDGGGIFSFLPQASDKTHFEELFGTPTGLDFRHAAALYGGTYTCPETWEAFKDAYQPQADKPGLHIIELKTDRTSRVQFHRDLLQAAVREVKKEWKL
>NZ_CP053764.1|WP_172614923.1|2905325_2906150_-|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
METVTVKTSDGVCYRAADSGHESSEAIVCLHGFTGSKESWMFLRGMFPGERMVMIDCLGHGETDAPVQVARYSASRQVADLAAVFDQLKLHKVKLIGYSMGGRLAYSFAQAFPPRVSALVLESTTPGLSTLQERKKRIQSDRKLADFILREGITSFVDYWESIPLFATQLSLPDSVKASIRAGRLKNNPPGLAGSLLGMGTGSQPSWWEALHRIKAPVLLICGEWDEKFCAINQKVHNLLPSSKIEVVKQAGHTVHVEQPRIFGKIVSEFLYGL
>NZ_CP053764.1|WP_003152221.1|2904448_2905267_-|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MAAEWKSERQYDEILYETYNGIAKITINRPEVHNAFTPKTVSEMIDAFACARDDSNIGVIVLAGAGDKAFCSGGDQKVRGHGGYVGDDQIPRLNVLDLQRLIRVIPKPVVAMVSGYAIGGGHVLHIVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKLEEETIKWCEEMLEKSPTALRFLKAAFNADTDGLAGIQQFAGDATLLYYTTDEAKEGRDSFKEKRSPDFGQFPRFP
>NZ_CP053764.1|WP_172614922.1|2902897_2904361_-|o-succinylbenzoate--CoA-ligase
MLTEQPNWLIQRAQLTPERIALIFENKQMTFRELYHASKQMAARLSKYCSLKKGDRAAILLSNRPEMVYAVHACFLLGAEAVLLNTKLSKQERLFQLEDSQAKLLLTEDGFCREEYESAVATADVDELQAEEAGDMEPEAYVTLDDTATLMYTSGTTGRPKGVQQTFGNHYSSAVSSALNLGVTERDRWLIALPLFHISGLSALFKSVIYGMPVVLHQKFSVTDVLDSISSHQVTIISAVQTMLSGLLAETEQCPASLRCILLGGGPAPLPLLEECRRKQFPVFQSYGLTETCSQIVTLSPEFSMDKLGSAGKPLFSCEIRIEKDGNPCAPFEHGEITVKGPNVMKGYYHRDDANQAAFHNGWFKTGDLGYLDDEGFLYVLDRRSDLIISGGENIYPAEVEAALLAHPAVAEVGVSGAEDPKWGKVPHAFLVLTSSVSSEELTAFCRERLAKYKIPAAFFEVDELPRNASNKLMRHRLNELRKGELS
>NZ_CP053764.1|WP_172614921.1|2901785_2902901_-|o-succinylbenzoate-synthase
MIKIEKITLYHVSMRLKKPFKTSIETLQDRKFLIVEAIDETGRTGWGEVSAFSSPWYTEETIQTCAHMLRDFFIPNVVGREFFHPSEVPDSLARFKGNRMAKAGLESAVWDLYAKKKGISLAEALGGKRDKVPAGVAVGLASADEMLREIEQYVKEGYQRIKIKIQPRHDVDLVRAIRSRFPNVPLMADANSAYELKDISRLKELDEFQLMMIEQPLQADDIVDHRHLQKHLRTAVCLDESICSYDDARRAIELGSCKIINIKPARVGGLTEALKIHDLCREHHMPVWCGGMFETGISRAQTVALASLPQFTIPGDISSSDRYWEEDIVTPDIRIEEGFISVPDGPGLGVEVNQEIMRKYVTQMDVFTTNN
>NZ_CP053764.1|WP_003152224.1|2901239_2901398_+|DUF1540-domain-containing-protein
MDQKILCEVNNCSYWGRGNKCTADAIYVVSHTGETAEKSEETDCKTFKPQDL
>NZ_CP053764.1|WP_017418423.1|2900141_2901182_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MDITMDALIAISIVWGFVFIYAVMATMDFGAGFWSMIYLNREQTKATNIANRYLSPTWEVTNVFIVAIVVALFSFFPGATFVLGTVLLIPGSIILLLLAIRSGFLVFSNTAKERKIMRYISGISGFIIPAVLILVLPVTHGGFIEKTGGVYQLNLANVFTSLNAYAFIGFAILSTLFLSSLLLADFSNVAEEEHAYRIYRRSSLITGPLSLLFAFFIMLTLRSEAGWLYTGMMKDKTWLILSVITFIIAGVALFLPNKRFGRNLGKPRIAMIAIALQYFLASYAYGRAHLPYMIYPDITVMSGFTEPATFRALFMTYIVAFIILFPGFYFFWKLFMKDRRYIRQEE
>NZ_CP053764.1|WP_146284167.1|2918324_2918906_+|energy-coupled-thiamine-transporter-ThiT
MNHSTQLVRLIEIAIMTGAAVILDIVSGMFLRMPQGGSVSIMMIPIFLISFRWGVKAGLTTGFLTGIVQIAIGNLFLQHPVQLFLDYIAAFAVLGFSGLFASGVRASALNKKRGALTMYVIGGVFIGSALRYAAHVVSGAVFFGSYAPKGTPVWIYSSVYNATYMIPSFILSAIVLILLFMTAPRLLEAKRTN
>NZ_CP053764.1|WP_024085720.1|2918936_2920466_-|flotillin-family-protein
MTMPIIIVIGIVFFLLIALIAVFITKYRTAGPDEALIVTGSYLGNKNVHIDEGGNRLKIVRGGGTFVLPVFQQAEPLSLLSSKLDVSTPEVYTEQGVPVMADGTAIIKIGGSIGEIATAAEQFLGKSKDDREQEAREVLEGHLRSILGSMTVEEIYKNREKFSQEVQRVASQDLAKMGLMIVSFTIKDVRDKNGYLESLGKPRIAQVKRDADIATAEADKETRIKRAAADKDAKKSELERATEIAEAEKINQLKMAEYRREQDTAKANADQAYDLETAKARQQVTEQEMQIKIIERQKQIELEEKEILRRERQYDSEVKKKADADRYSVEQAAAAAKAKQLAEADAEQYSIEAMAKAEAERVRIDGLAKAEAEKARGETEAEVIRLKGLAEAEAKEKIADAFEKYGQAAILDMIVKMLPEYAKQVSAPLSNIDKITVVDTGGSGENGGANKVTGYATNLMAGLQESLKASSGINVKELIENFSGKGNIKQSINELTKELSDSNERHSPE
>NZ_CP053764.1|WP_032876878.1|2920485_2921016_-|NfeD-family-protein
MDIFHLPLETVYLYTLIISGSLTLLILFFQDVFHGLSEAIPVSFLNPALILSFLTIFSASGYIGEIAAPLSSPVIALLSFVLSVLLVSLLHFFVLVPLSSAEESLAYRETDLKGRVGRVITSVPKDGYGEVIIEGIGGAISKSAVSFDQEQIKYGTAVLVIDVKDGVLFVTPHEPI
>NZ_CP053764.1|WP_070082256.1|2921161_2921650_+|DinB-family-protein
MSIFNEARQQTWEVLKGLSDEEFNRKPAADEWSVREVLDHLKKIDETAQTLLSKQAKDAPFKKIEDKPMEFIEDRSNKRPAPSHLEPEQNRISVIEAKQELDTARQQLTAVISSLNEEDFERVLPHPVFQELTIRQWIDFIGHHEKRHINQIEEIKQKIEKV
>NZ_CP053764.1|WP_003152182.1|2921651_2922233_-|MOSC-domain-containing-protein
MWKRITAKTEGVYIADTEQFVTKKMDKLRAEYGGFPGDLHFGLTKKAGAREPMYERGTEIFNRRQISIVSMEECDDIAEKMGISHIFPEWLGANIAISGFSALTPLKEGSRMIFPSGASLLCEGENDPCIQPGEVIQSFYPDQPKLAAAFVRHAMGRRGIVCIVERPGDICTGDAVTIHSYEPKRAKKKIEKV
>NZ_CP053764.1|WP_003152181.1|2922304_2923513_-|choline-dehydrogenase
MTLNMKVESMHKFHTFEIPTVIKHGIGAIQHAGSEVRALGVTKALLVTDPGIYNAGVANPVIESLQEAGIEVVLFNKVEPNPPVRLVNEGSELYKKENCNGLVAVGGGSSMDTAKAIGVEATHEGSVLDYEAAEGKKPLENRIPPLTTIPTTAGTGSEVTQWAVITDEEREFKFNTGGPLIAAHLTVIDPELHTSMPPHVTAMTGIDALAHAIECYTMKFAQPITDAVALMAIEYAAHYIKRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEYNWKGYPEKFARIAKAFGIDTSNMTTEEAAKASVNWMYDLVKDLEVPSLEEQGVSPDMIERLSKEAMKDPQTFGNPRDLNEKAYNWIYKRCFDLTPKTV
>NZ_CP053764.1|WP_003152180.1|2923529_2925002_-|betaine-aldehyde-dehydrogenase
MSKTLYIGGEWISAEKKQTRRIINPFNQEEIATVCEGDRDDAVKAIAAARKAFDEGEWPVLSGLERGQFVLKIAELIRRDLNELAELESLDTGKTIEESKADMDDIANVFQYYAGLADKDGGEVISSPIPDSVSKIVREPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVLKPSEITPLTTIKVFQLIEEAGIPKGAANLVLGPGASVGDELARNLDVDLVSFTGGIETGKKIMQAASGNVKKIALELGGKNPNIVFQDADLETAADQALNAVFFHAGQVCSAGSRLLVDEAIHDEFLAELIKRTKRIKLGNGFHEDTESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPDDPALQNGFFYEPTIFSNCKSDMRIVQEEIFGPVLTVESFSSEEEVIRLANDTIYGLAGAVWSKDIEKCERVAAKLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEIKHIYRNTKPAAVNWFQA
>NZ_CP053764.1|WP_003152179.1|2925202_2925757_+|GbsR/MarR-family-transcriptional-regulator
MDENPEFAAIEQARDLVIDSIAETMDLYGITRSVGILYGTMYMRDEMTLDEMREELQMSKPSMSTGVKKLQDLNVVKKTFHRGTRKHTFVAEKDFFTFFTNFFPPKWDREVQVNLSAIVQAQADLQSVLLAEEGSAELQEEARQLYDQLESSKAYYHWLKRLADSVQSGEIFKFIPIETDEKNA
>NZ_CP053764.1|WP_070082729.1|2925917_2926457_+|DUF1016-domain-containing-protein
MKQKFFSTVMASLFGLVLLLSLPTASFAAESGSTVHEPEMSAKATATLFAKYTGASQQEWSFSDIELTYRPNTILSLGVMEFTLPSGFAATTKDTVNGHALRERQILNNGKTVRLPLNIDLLGAAEFKLSLNNKTLPAAGTYKFRAENKSLSIGSKFYAEDTIVVQKRSTPPTQPCNCK
>NZ_CP053764.1|WP_058906302.1|2926620_2927289_+|TrkA-family-potassium-uptake-protein
MGKIKNKQFAVIGLGRFGGSICKELFKMGHEVLAIDISEERVNAYSSYATHAVRANSTEESELQSLGIRNFEYVIVAIGANIQASTLTTLLLKELNIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVRIAQSLSDENVLNYIDLSDEYSIVELSATKKLHLKSILDLGVRARFGCTILAVKHNGDIQLSPSPETVIHECDCLVLMGHKRDIKRFETEGM

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP015439	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence	255887-255944	7	0.879
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	483791-483848	8	0.862
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NC_004604	Bacillus megaterium QM B1551 plasmid pBM400, complete sequence	46420-46477	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	838-895	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	75825-75882	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	10419-10476	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	70766-70823	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	1320-1377	9	0.845
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_CP015440	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence	64775-64832	10	0.828
NZ_CP053764_1	1.1\|2911330\|58\|NZ_CP053764\|CRISPRCasFinder	2911330-2911387	58	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	57361-57418	13	0.776

1. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP015439 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence) position: , mismatch: 7, identity: 0.879

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatattatatacgacggt	Protospacer
*******************************************.**.* *. *.**.*

2. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.862

cagcttggaaggctgaggttttaccactaaactacacccgcatgtt-----gtttggggc	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatggttaaaagttttgc--	Protospacer
******************************************** *     **** *

3. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NC_004604 (Bacillus megaterium QM B1551 plasmid pBM400, complete sequence) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgt-ttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccattaaactacacccgcatgttttcttaaaatgg-	Protospacer
**************************.******************* * **.....*.

4. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat--	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatat--tttaaagtggcgg	Protospacer
*******************************************.*  ***...*.*..

5. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat--	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatat--tttaaagtggcgg	Protospacer
*******************************************.*  ***...*.*..

6. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat--	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatat--tttaaagtggcgg	Protospacer
*******************************************.*  ***...*.*..

7. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat--	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatat--tttaaagtggcgg	Protospacer
*******************************************.*  ***...*.*..

8. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 9, identity: 0.845

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat--	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatat--tttaaagtggcgg	Protospacer
*******************************************.*  ***...*.*..

9. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_CP015440 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence) position: , mismatch: 10, identity: 0.828

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcataataatatataccat	Protospacer
*******************************************. *. *  . .* **

10. spacer 1.1|2911330|58|NZ_CP053764|CRISPRCasFinder matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 13, identity: 0.776

cagcttggaaggctgaggttttaccactaaactacacccgcatgttgtttggggcgat	CRISPR spacer
cagcttggaaggctgtagttttaccactaaactacacccgcatagtaagtagttctta	Protospacer
*************** .**************************. *.  *.*  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

672600 : 682491

Synechococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007408896.1\|672600_673893_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.5e-19	27.3
WP_146283754.1\|673968_674688_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	3.7e-47	44.3
WP_003155758.1\|674687_674942_+	phosphoribosylformylglycinamidine synthase subunit PurS	M4QPE7	Synechococcus_phage	4.7e-05	33.3
WP_007408898.1\|674938_675622_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_172614506.1\|675605_677834_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.5e-158	40.8
WP_060674456.1\|677809_679240_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_015388588.1\|679331_680372_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.4e-63	41.1
WP_172614507.1\|680368_680956_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.3e-25	38.8
WP_025853962.1\|680952_682491_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	8.7e-78	50.8

DBSCAN-SWA_2

1124372 : 1157971

Planktothrix_phage(16.67%)

tRNA,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014304785.1\|1124372_1125365_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_039062894.1\|1126108_1127743_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003155043.1\|1127849_1128785_+	ABC transporter permease	NA	NA	NA	NA
WP_003155041.1\|1128788_1129706_+	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_003155039.1\|1129718_1130795_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-16	29.9
WP_017417453.1\|1130787_1131705_+	oligopeptide ABC transporter ATP-binding protein OppF	M1HP82	Acanthocystis_turfacea_Chlorella_virus	1.5e-05	24.6
WP_172614591.1\|1131811_1132999_+	putative glycoside hydrolase	NA	NA	NA	NA
WP_172614592.1\|1133116_1133695_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003155034.1\|1133873_1134269_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_003155033.1\|1134326_1134983_-	TerC family protein	A0A0S4KZH7	Pseudomonas_phage	3.8e-30	40.4
WP_003155032.1\|1135258_1135915_+	adaptor protein MecA	NA	NA	NA	NA
WP_128574781.1\|1136065_1137226_+	competence protein CoiA	NA	NA	NA	NA
WP_003155028.1\|1137453_1139283_+	oligoendopeptidase F	NA	NA	NA	NA
WP_165408905.1\|1139320_1139488_-	hypothetical protein	NA	NA	NA	NA
WP_003155024.1\|1139773_1140676_-	DsbA family protein	NA	NA	NA	NA
WP_003155023.1\|1140672_1141071_-	thiol management oxidoreductase	NA	NA	NA	NA
WP_077722057.1\|1141299_1141974_-	lytic transglycosylase domain-containing protein	A0A1P8CWQ1	Bacillus_phage	7.8e-39	71.2
WP_077722058.1\|1141978_1142554_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_070081630.1\|1142680_1143046_+	hypothetical protein	NA	NA	NA	NA
WP_003155019.1\|1143073_1143709_+	GTP diphosphokinase	NA	NA	NA	NA
WP_003155018.1\|1143726_1144527_+	NAD kinase	NA	NA	NA	NA
WP_102421729.1\|1144541_1145435_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	1.0e-06	29.3
WP_070081632.1\|1145467_1146217_-	bis(5'-nucleosyl)-tetraphosphatase PrpE	A0A1V0SJW2	Klosneuvirus	9.0e-12	26.8
WP_172614593.1\|1146444_1148289_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_003155011.1\|1148538_1149246_+	thiaminase II	NA	NA	NA	NA
WP_061890947.1\|1149223_1149841_+	thiazole tautomerase TenI	NA	NA	NA	NA
WP_172614594.1\|1149824_1150934_+	glycine oxidase ThiO	NA	NA	NA	NA
WP_003155008.1\|1150930_1151134_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_088005363.1\|1151130_1151901_+	thiazole synthase	NA	NA	NA	NA
WP_014304797.1\|1151897_1152908_+	thiazole biosynthesis adenylyltransferase ThiF	NA	NA	NA	NA
WP_172614595.1\|1152930_1153743_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_003155001.1\|1153873_1154650_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_172424049.1\|1154741_1155356_+\|coat	spore coat protein	NA	NA	NA	NA
WP_007409091.1\|1155414_1155858_-\|coat	spore coat protein	NA	NA	NA	NA
WP_007409090.1\|1156006_1156489_-\|coat	spore coat protein	NA	NA	NA	NA
WP_015417225.1\|1156639_1157140_-\|coat	spore coat protein	NA	NA	NA	NA
WP_172614596.1\|1157232_1157547_-\|coat	spore coat protein	NA	NA	NA	NA
WP_003154992.1\|1157584_1157971_-\|coat	spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_3

1216007 : 1247843

Bacillus_phage(30.0%)

terminase,plate,portal,holin,capsid,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_087920760.1\|1216007_1217144_+	S9 family peptidase	A0A1P8CWN8	Bacillus_phage	1.3e-94	47.9
WP_003154881.1\|1217133_1217268_+	PhrA family phosphatase inhibitor	NA	NA	NA	NA
WP_077722093.1\|1217409_1218363_+	N-acetylmuramoyl-L-alanine amidase	A0A218KC88	Bacillus_phage	1.4e-62	69.3
WP_007610770.1\|1218401_1218779_-	PH domain-containing protein	A5GYQ0	Lactococcus_phage	1.5e-15	41.4
WP_077722094.1\|1218887_1219493_+	poly-gamma-glutamate hydrolase family protein	A0A0Y0AJU6	Bacillus_phage	2.8e-40	46.8
WP_172614616.1\|1219482_1219632_+	hypothetical protein	NA	NA	NA	NA
WP_003154873.1\|1219647_1220238_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	3.0e-39	51.7
WP_003154871.1\|1220386_1220725_-	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	8.4e-18	45.8
WP_003154869.1\|1220916_1221096_+	hypothetical protein	NA	NA	NA	NA
WP_077722095.1\|1221085_1221913_+\|portal	phage portal protein	S6BFM4	Thermus_phage	1.3e-19	49.0
WP_063174228.1\|1221812_1222613_+	ATP-binding protein	A6XMI1	Bacillus_virus	6.1e-59	45.1
WP_095836059.1\|1222612_1222780_+	hypothetical protein	NA	NA	NA	NA
WP_039251797.1\|1222877_1223219_+	hypothetical protein	NA	NA	NA	NA
WP_003154859.1\|1223208_1223412_+	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	5.4e-12	48.5
WP_017417605.1\|1223525_1224038_+	sigma-70 family RNA polymerase sigma factor	A0A0K2CNQ1	Brevibacillus_phage	2.9e-22	43.9
WP_025851819.1\|1224150_1224948_+\|terminase	terminase small subunit	A0A0S2MVB6	Bacillus_phage	7.2e-60	49.8
WP_077722096.1\|1224944_1226243_+\|terminase	PBSX family phage terminase large subunit	M4ZRM5	Bacillus_phage	9.4e-150	58.9
WP_088037172.1\|1226291_1227671_+\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	2.3e-138	55.6
WP_015417286.1\|1227702_1228548_+	hypothetical protein	A0A1B1P7E4	Bacillus_phage	4.3e-55	57.6
WP_007407274.1\|1228574_1229510_+\|capsid	phage major capsid protein	A0A1B1P7E3	Bacillus_phage	3.3e-104	62.8
WP_003154846.1\|1229526_1229910_+	DUF3199 family protein	NA	NA	NA	NA
WP_007610806.1\|1229906_1230263_+	DUF3599 family protein	NA	NA	NA	NA
WP_043867016.1\|1230259_1230763_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	1.2e-36	40.4
WP_069473357.1\|1230759_1231206_+\|portal	phage portal protein	NA	NA	NA	NA
WP_063095512.1\|1231202_1231412_+	hypothetical protein	NA	NA	NA	NA
WP_044053125.1\|1231411_1232809_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7RTT5	Clostridium_phage	9.0e-82	40.4
WP_003154837.1\|1232810_1233254_+\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	8.4e-26	45.2
WP_032874591.1\|1233330_1233777_+\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	1.0e-10	35.8
WP_015239684.1\|1233818_1233971_+	hypothetical protein	NA	NA	NA	NA
WP_172614617.1\|1233958_1239001_+	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	1.9e-41	46.6
WP_077722098.1\|1238993_1239653_+	LysM peptidoglycan-binding domain-containing protein	G3MBQ1	Bacillus_virus	3.1e-08	44.2
WP_039251762.1\|1239666_1240644_+	hypothetical protein	A0A1L6BY20	Clostridium_phage	2.9e-34	30.9
WP_003154827.1\|1240643_1240910_+	DUF2577 family protein	S6C459	Thermus_phage	3.4e-06	37.5
WP_003154825.1\|1241013_1241439_+	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	1.5e-11	35.9
WP_070081679.1\|1241431_1242478_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.0e-69	44.1
WP_007407262.1\|1242461_1243040_+	YmfQ family protein	A0A2H4J717	uncultured_Caudovirales_phage	3.1e-12	31.0
WP_003154822.1\|1243036_1243309_+	hypothetical protein	NA	NA	NA	NA
WP_077722100.1\|1243311_1244901_+	hypothetical protein	A0A2H4J4R1	uncultured_Caudovirales_phage	6.3e-15	55.4
WP_077722101.1\|1244913_1245339_+	hypothetical protein	NA	NA	NA	NA
WP_168237133.1\|1245343_1245541_+	XkdX family protein	NA	NA	NA	NA
WP_146276587.1\|1245597_1246359_+\|portal	phage portal protein	NA	NA	NA	NA
WP_146276589.1\|1246410_1246674_+	hemolysin XhlA family protein	A0A2H4JD40	uncultured_Caudovirales_phage	1.1e-22	63.1
WP_003154813.1\|1246687_1246951_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	2.3e-23	65.5
WP_058905962.1\|1246964_1247843_+	N-acetylmuramoyl-L-alanine amidase	Q9ZXD7	Bacillus_phage	2.8e-81	60.5

DBSCAN-SWA_4

1800742 : 1806956

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003154061.1\|1800742_1801135_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	G3MBF1	Bacillus_virus	3.8e-30	59.1
WP_007611605.1\|1801094_1803197_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	U5PY35	Bacillus_phage	0.0e+00	85.7
WP_024085331.1\|1803214_1804204_+	class 1b ribonucleoside-diphosphate reductase subunit beta	F8WQ21	Bacillus_phage	2.5e-155	83.3
WP_172614705.1\|1804252_1804873_+	hypothetical protein	A0A127AYS1	Bacillus_phage	1.6e-46	48.4
WP_069013563.1\|1804922_1805681_-	N-acetylmuramoyl-L-alanine amidase	E5DV68	Deep-sea_thermophilic_phage	6.2e-53	50.4
WP_015417523.1\|1805987_1806956_+	stage V sporulation protein K	G3MAX6	Bacillus_virus	8.0e-53	40.9

DBSCAN-SWA_5

2240297 : 2246550

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_160223149.1\|2240297_2240891_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.9e-14	36.0
WP_007409427.1\|2240880_2241636_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.9e-10	25.7
WP_003153376.1\|2241843_2241933_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_172614792.1\|2242020_2242542_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_003153373.1\|2242607_2242982_-	GNAT family N-acetyltransferase RibT	NA	NA	NA	NA
WP_003153372.1\|2243098_2243563_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.2e-43	59.3
WP_094247822.1\|2243595_2244792_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.7e-116	54.9
WP_007409425.1\|2244806_2245454_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-39	44.3
WP_015388054.1\|2245434_2246550_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.2e-55	36.9

DBSCAN-SWA_6

2605712 : 2665843

uncultured_Mediterranean_phage(25.0%)

protease,tRNA,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007408194.1\|2605712_2606156_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_060674703.1\|2606168_2608373_-	GTP diphosphokinase	A0A2I2L310	Orpheovirus	1.5e-09	34.8
WP_003152714.1\|2608530_2609043_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.5e-29	47.2
WP_172614866.1\|2609048_2611409_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.4e-90	34.6
WP_003152709.1\|2611464_2611791_-	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_012118088.1\|2611854_2612352_-	cation:proton antiporter regulatory subunit	NA	NA	NA	NA
WP_077722642.1\|2612483_2614703_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.0e-27	31.7
WP_003152702.1\|2614739_2615036_-	post-transcriptional regulator	NA	NA	NA	NA
WP_070082162.1\|2615151_2616708_+	stage V sporulation protein B	NA	NA	NA	NA
WP_172614867.1\|2616715_2617372_-	DUF421 domain-containing protein	NA	NA	NA	NA
WP_003152697.1\|2617538_2617925_+	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_003152695.1\|2617978_2618239_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	1.5e-06	46.9
WP_172614868.1\|2618269_2619415_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.8e-89	44.8
WP_077722643.1\|2619442_2620471_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_003152687.1\|2620496_2620697_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_003152685.1\|2620689_2621694_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	4.0e-07	30.0
WP_003152683.1\|2621704_2622310_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_012118093.1\|2622444_2622954_-	BofC C-terminal domain-containing protein	NA	NA	NA	NA
WP_069013531.1\|2623338_2623932_-	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_071391551.1\|2624079_2625285_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_024085652.1\|2625411_2626515_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_172614869.1\|2626516_2627365_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_060674722.1\|2627346_2628912_-	L-aspartate oxidase	NA	NA	NA	NA
WP_146277253.1\|2629017_2630169_+	IscS subfamily cysteine desulfurase	A0A1X7C038	Faustovirus	1.7e-30	26.5
WP_014305508.1\|2630165_2630708_+	transcription repressor NadR	NA	NA	NA	NA
WP_003152668.1\|2630733_2631591_-	prephenate dehydratase	NA	NA	NA	NA
WP_007408173.1\|2631604_2632048_-	transcriptional regulator ThrR	NA	NA	NA	NA
WP_003152665.1\|2632101_2633388_-	GTPase ObgE	NA	NA	NA	NA
WP_003152664.1\|2633419_2633998_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_003152662.1\|2634315_2634600_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_060674727.1\|2634612_2634954_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003152660.1\|2634956_2635265_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_003152659.1\|2635410_2636277_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_007408168.1\|2636269_2637073_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_060674730.1\|2637200_2638004_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_003152653.1\|2638006_2638687_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_172614870.1\|2638740_2639259_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_003152649.1\|2639255_2640119_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_003152647.1\|2640149_2641163_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_007408165.1\|2641254_2641950_-	DNA repair protein RadC	NA	NA	NA	NA
WP_070082167.1\|2641981_2642551_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_146277259.1\|2642691_2643693_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_071391543.1\|2643819_2644572_-	prepilin peptidase	NA	NA	NA	NA
WP_172614871.1\|2644711_2646004_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_071391541.1\|2646062_2648705_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	3.7e-161	42.2
WP_060674742.1\|2649157_2649349_+	hypothetical protein	NA	NA	NA	NA
WP_060674860.1\|2649363_2650386_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_172614872.1\|2650419_2652564_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_146277263.1\|2652696_2653986_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_094247687.1\|2654014_2654989_-	porphobilinogen synthase	NA	NA	NA	NA
WP_070082173.1\|2654991_2655774_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_172614873.1\|2655763_2656705_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_003152629.1\|2656739_2657570_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_003152628.1\|2657577_2658945_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_014305520.1\|2659139_2659631_+	hypothetical protein	NA	NA	NA	NA
WP_003152626.1\|2659663_2660251_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_052827698.1\|2660247_2662572_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.4e-183	44.2
WP_003152622.1\|2662771_2664430_-\|protease	ATP-dependent protease LonB	A0A167RA83	Powai_lake_megavirus	1.9e-14	32.7
WP_003152620.1\|2664580_2665843_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.2e-147	65.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage