CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP048104	Kroppenstedtia pulmonis strain W9323 chromosome, complete genome	10 crisprs	cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,csa3,WYL,DEDDh,cas3,cas6,cas4,cas14j,RT	0	1	3	0

1. NZ_CP048104

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP048104_2

• CRISPR_ID: NZ_CP048104_2
• CRISPR_location: 1038192-1038356
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_CP048104_2

Consensus_repeat	Method
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTAAGATCAAAACC	PILER-CR

spacers of NZ_CP048104_2

>2.1|1038222|36|NZ_CP048104|CRISPRCasFinder
TTTTGGGATATCATGATATCGGAACAGGAGGGAATC
>2.2|1038288|38|NZ_CP048104|CRISPRCasFinder
CTTTCCGTCTTCGTTCGCGATTTCTTCTGTCATGCTCT
>2.3|1038230|35|NZ_CP048104|PILER-CR
TTTGGGATATCATGATATCGGAACAGGAGGGAATC
>2.4|1038296|37|NZ_CP048104|PILER-CR
TTTCCGTCTTCGTTCGCGATTTCTTCTGTCATGCTCT

CRISPR arrays and Neighbor proteins around NZ_CP048104_2

CRISPR arrays

The CRISPR arrays of NZ_CP048104_2

>merge|NZ_CP048104|2|1038192-1038356|CRISPRCasFinder,PILER-CR
TCTTTTTTTTCTCATAGGTAAGATCAAAACTTTTGGGATATCATGATATCGGAACAGGAGGGAATCGTTTCAATTCCTCATAGGTAAGATCAAAACCTTTCCGTCTTCGTTCGCGATTTCTTCTGTCATGCTCTGTTTCAATTCCTCATAGGTAAGATCAAAACC

>NZ_CP048104|2|2|1038192-1038355|CRISPRCasFinder
TCTTTTTTTTCTCATAGGTAAGATCAAAAC	TTTTGGGATATCATGATATCGGAACAGGAGGGAATC
GTTTCAATTCCTCATAGGTAAGATCAAAAC	CTTTCCGTCTTCGTTCGCGATTTCTTCTGTCATGCTCT
GTTTCAATTCCTCATAGGTAAGATCAAAAC

>NZ_CP048104|2|2|1038199-1038356|PILER-CR
TTTCTCATAGGTAAGATCAAAACTTTTGGGA	TATCATGATATCGGAACAGGAGGGAATCGTTTCAA
TTCCTCATAGGTAAGATCAAAACCTTTCCGT	CTTCGTTCGCGATTTCTTCTGTCATGCTCTGTTTCAA
TTCCTCATAGGTAAGATCAAAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein	unknown	unknown	gnl|CDD|225279
NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase	unknown	unknown	gnl|CDD|223498
NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein	unknown	unknown	gnl|CDD|378910
NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit	unknown	unknown	gnl|CDD|223564
NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl|CDD|349967
NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein	unknown	unknown	gnl|CDD|226481
NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase	unknown	unknown	gnl|CDD|225357
NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein	unknown	unknown	gnl|CDD|238206
NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein	unknown	unknown	gnl|CDD|377252
NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein	unknown	unknown	gnl|CDD|378910
NZ_CP048104.1|WP_173221092.1|1048913_1049810_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173218907.1|1035368_1035542_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221077.1|1039586_1039883_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein	unknown	unknown	gnl|CDD|273257
NZ_CP048104.1|WP_173221071.1|1035753_1036068_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein	unknown	unknown	gnl|CDD|376356
NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease	unknown	unknown	gnl|CDD|223884

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein	gnl|CDD|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	2.54025e-87
NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	6.81333e-30
NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	9.69508e-18
NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein	gnl|CDD|378910	pfam12671, Amidase_6, Putative amidase domain.	1.08732e-46
NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit	gnl|CDD|223564	COG0490, COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism].	2.42731e-55
NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl|CDD|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	4.63765e-94
NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein	gnl|CDD|226481	COG3972, COG3972, Superfamily I DNA and RNA helicases [General function prediction only].	1.87247e-19
NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	5.93549e-18
NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase	gnl|CDD|225357	COG2766, PrkA, Putative Ser protein kinase [Signal transduction mechanisms].	0
NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein	gnl|CDD|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	6.14338e-26
NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein	gnl|CDD|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	3.03674e-72
NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein	gnl|CDD|378910	pfam12671, Amidase_6, Putative amidase domain.	5.61067e-37
NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein	gnl|CDD|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	1.67526e-106
NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.3245e-50
NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein	gnl|CDD|376356	pfam00586, AIRS, AIR synthase related protein, N-terminal domain. This family includes Hydrogen expression/formation protein HypE, AIR synthases EC:6.3.3.1, FGAM synthase EC:6.3.5.3 and selenide, water dikinase EC:2.7.9.3. The N-terminal domain of AIR synthase forms the dimer interface of the protein, and is suggested as a putative ATP binding domain.	6.75372e-05
NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease	gnl|CDD|223884	COG0814, SdaC, Amino acid permeases [Amino acid transport and metabolism].	5.12421e-49

Protein sequences

>NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein
MSSMQDGFNSKPTSDEDLQKVRMGELKPHNAPITLVEYDSRWPELFEGEANRVRSALGNKALQVEHVGSTSVPGLCAKPIIDMILVVADSADEPSYVPTLEAAGYTLWIREPEWFEHRLLKGPDIDINLHVFSAGTSEIERMLRFRDWLRANDTDRDNYARAKRSLARRVWRHVQHYADAKTAIIQEIMDRANAAE
>NZ_CP048104.1|WP_173221071.1|1035753_1036068_+|hypothetical-protein
MEKNGIDQHKDGYLQYVQQEAKEIGKVFILDTGEGNDLEDPVTGWYVEDLSGWLIDSRLKEQFLIDLEESKHWDTFDGYYVFVEWKLKDNNEIEIKFVKYPLYE
>NZ_CP048104.1|WP_173218907.1|1035368_1035542_+|hypothetical-protein
MDMDSKKLQFGNATVIVHSPLANMTEEERKAWYDQQWERKNPLMYEIARAIFDCQRD
>NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein
MNRPNGLDCFIYLRKSRTDIEEEKKALKEGFSFDVLERHRKQLLELAKQEQHNILDIYEEVVSGEHLLDRPQIQQMLKLVEQGHCAGVLVMDLDRLGRGDMYDMGMIYRSFQYSETLIVTPTEVIDPNSDGAELLFGVKSILSREELKGITKRLQRGRQISAREGKSISKKPPYGYIRDETLKLHPDPETSWVVKNIFERVVEGAGRIQIAQELDEMGVTSPRGEGPWSPSTIAAIIKNEVYMGHIIWGKIQYIKRGGGKYTRKRVPPDQWHRHDHAHEPLVSEELFKEANLALSGRWRPPTKKANKLTNPLAGILQCERCGRAIRYFPRKDRPNDDMRCIWPGCRGKQRGCSFPFVEKAILDGIRYLLQQYEAIDEVNREKKDNVISLKEKGSENLKKELDDLNTQRNRLHDFLEQGVYDIATFRERQQVVVTRIRKAEDQLKEIEREIEKEKIRVKQQKEVIPKLWNVIEAYQKTHDPLKKNRLLKTVLEKATYFRDPTWTEPGKIRIHVYQRIW
>NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase
MDILSRIAQQRKKEEELAWEGSFREYLQMVQKRPELAQTAHSRVYRMIADSGIEKDEQGNISYLFFSRELFGLDQAIERLVEEYFHSAARRLDVRKRILLLMGPVSGGKSTIVTLLKRGLERYSRTEAGALYGIKGCPMQEDPLHLIPYNMREELEKEWGVKIEGNLCPSCRMRLEKEYNGRVEDVRIERVLISEDNRVGIGTFSPSDPKSQDIADLTGSIDFATITEYGSESDPRAYRFDGELNKANRGLMEFQEMLKCDEKFLWNLLSLTQEGNFKAGRFALISADELIMAHSNEAEYKSFISNKKNEALHSRIIVMPIPYNLKVSEEERIYEKLVRQSDLGHVHIAPHALATASVFSILTRLKPSKKQGLDLIKKMRLYDGKSVEGYKESDVGELRNEHLDEGMSGIDPRYVINRISSALIRSQADCINALDILRSIKDGLDQHPSITQEERERYLNFISIARKEFDELAKKEVQKAFVYSYEESAKTLLDNYLDNVEAFCNWNKLQDPLTGEELDPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFDYNSHDRLREAIQKKLFADLKDVVKITTSTKTPDENQLKKVNEVTATLIDKYGYCPTCANDLLRYIGSLLNR
>NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein
MIELRKLFKIRFVLVALLGLTLVVSGCSSDTAKVADSKEVARTPEEDSSQDEADSIFDEEISKEISYYDESSKSKKEIEKNNQPAIQIVKQTSQKNQVKVEADLDKAQFRDMVRATAADLQSLKPHERKQVINLVKDINQYENKKINNEIKKLKSKADKGTLSGAEKAKLLSLLPIDKKGVKVKPEQKINPDQVPPASDLKDKKPGNSNPDKLLPEKPGKEEQTQPEKETPKPGNKTPQPGDKEDEPENEQTEPGENQESGQDNENQQENEEQDQNDGNDQNEQEPQQPDNENTEEEEKPESKDPGKDKDQQKDTEKSMVEKNGYDRAKARDYAYKWWNKRNNEEYGYYSKAMGGCYSCWYDCTNFTSQALKAGGLKEWKSDPWWYYSDKKPSYSWGVANSQYKHLEQRAKPAKSLSEVKVGDIVHGDFDHDQKIDHSAIVTKIQNGEIYLTYHTTDKKDVPLSYWFYYDYDVYVWKMGTANNQAR
>NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase
MKVKACCFDLDGTLLPMELDDFIAEYFRALVPYVAHLMPPKQFFVYMGDAMKRMIGDDDPNRTNEEVFMERFLSRSGLEQDKVWPLLERFYEEEFPKLRKYVTPTPVARQVVQAAMEQGMDVIVATNPVFPRAAIEERLRWAGVEDLIKWVTVYEESHFCKPHVQYYQEVAGRLGVLPEECVMIGNDMQEDMVAETIGMKTYFLKDCRIDRGEPVYHPNQEGNLNDLLEDIRNQRGVFQ
>NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MSFHICLVEPEIPNNTGNIARTCAVTGSILHLIRPLGFSTDDKYLKRAGMDYWHHVDVRYYDSFDEFQSSFPKGRFFCATTKAQKHYSSFEFREGDIFVFGKETAGLPSEILETYRETCMRIPMKPDIRSLNLGNSAAIVIYEALRQTGYPDLV
>NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein
MTKIALVTDSSCDLSSDLLSKFNIEVVPLRIIYAQTEYRDQVDITPNEVYDRLDEEVPTTSMPSPQDILETFEKLADTGYSHCIVISLSSGLSGTYQAFQMIAQNFDRMKIDIIDSKGLSWILGFLVLEAAQMIQEQFDYHEILERIKRIRQKIKGFFIVDTLEYLKKGGRIGKVAATLGSMLNLKPIITTDDQGLFTPYQLARGKKQAIKKMVEPLLKQLESTKASIAIIQGRAEVEAEALRLRLKDLDRIGNLYVSPVSPALVVHTGPGLIGIVINPEHS
>NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein
MMWRESLKGTVRMKTRSWRQPVASWFRGQSQVWVEGGIDRLFTWVQHQDADWVIKEQKRWERVRDLQEERKMKRLKGETRIRVIQEERLENGDIMMKVWVYQRYLYSIKERFFEQEESNGFSIQLAEGGAGWFIMKCKVEPEMNTEVERDWSYYQPPDFGTRSGSSYNRMKAVQYAETWWNGANPRYQKFEVDCTNYVSQCLHAGGIPMEYSYQRARGWWYRGSRENWSYSWAVAHSLKNYLDKGGVHRAEIVDSPRQLQPGDIICYDWDGNGRWQHNTVVTTLDASGEPLVNAHTVNSRHRYWDYRDSHGWTPQVQYRFYHIPD
>NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein
MDKQITWEYKRMSVTDEVLREQEKLLGIRLPDDFREVFIENHGAGPVPECYYASNGNGRNFGFLLALDKDEDGEVEFTDANSPYMKREHNMPNEVVIFSIDPAGNFLCFDYDQLNDGYPSIIFWDHEVEGGAVKKICNTFTELLQMLHEVGDEES
>NZ_CP048104.1|WP_173221077.1|1039586_1039883_+|hypothetical-protein
MFAYQYIMVDWLHNYGDEYPIRIYSEIDKNGFETRKVEIFPNNQIGYAFDSIEFGGTGLGMEPVLDLNEIAADPYETFIPKEISKEEFEKIWSMYIKD
>NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter
MDTLIFEVGLAIALIAVVGVLSTKLRFSVIPFYILVGMVVGPHAPHFGIIDLRFIESSVFIDFMGRLGVLFLLFYLGLEFSVGRLIKSGKSILIGGSFYVVLNFVSGLLLGWMMDYPLKETMVICGIMTSSSTAIVAKVLVDLKRTANPETEIIMGMIMFDDLFIAVHISILSGLVLSGASSWVGVLFTSLTALIFILLFIVIGRKLMPLIDKVLNVRSSELFLLLIIASLFLVSGFSETLHVAEAIGALLIGLVLAESVHAKRIEQLVLPFRDLFGAVFFFSFGLTIDPTSLGGAVWAALVGVLLTIIGNVLSGFFAGRASGLSGKSTANIGFTLVSRGEFSIIMANIGKEGNLMPVIQSFAVLYVLILAVIGPFMAKESKTIYGLCQKMMGRFRKRSTGT
>NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit
MDIRETDLPGIGRKYQVVTRTGEKAVVIIHDDGRREMYHFDPNDPDESISVVTLDDEEARQLAGIIGGMNYQPKALENIEIALEDLIIEWYKISPQAKCNGVTIGKLMVRQKTGATIIALIEKNQRKTINPGPDHVLASGTTLVIAGERKQINQLKQILSDGG
>NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein
MGWMPLGQKGFSLRKVRDLTVMDFQDSISLVIACDSLGGIGNKPWDQVQVPPETVGIFGVRVPLFEVIASGGVPIHVSDCLAVEMEDTGRRIIEGIRSYCAEAGVIEENQFNGSTEENVLTLQTGIGIMVTGWVEQGGFFPGCSEAGDVILCAGIPKSGPQFQISLEDPELLSLQELIRLRKDQGVGDLLPVGSKGVKYEAEQLAESAGLSVQLKEDVAVDLHRSGGPATCAVFSCKPGDMDRLANKLTTPLHQVGYLF
>NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein
MKQISRKHFIGSFSPSHSPMETVPLRESFWVETHDCYGGKIRTEQDLRPQINISPLNPSTGPIAVEGVRKGDIIRVSIEEIQLDDQGVMVMMPGLGPLGDMVQETHTKIIPIRDGTVYFSDNIHFPVQPMIGVLGVAPETGEISTATPGNHGGNMDTKEITTGSHVYFPVFIDGANLALGDLHAAMGDGEMDGTGIEIAGKVRLSVSKVPDFDLSMPLVETKQEYLIVSSQKTYDKAIQEGMKQAVSLLQYRLDLSFTEAYRLLSATGDLRISQIVNPCVTVKIAIPKSLFPKQTLFND
>NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease
MKKSKNHANTPSSSLRMEKISFWEGVALIVGANIGAGILSLAYGAKNAGWPVLVLWVAVAGIFTTISMLYVAETTLRTEKPLQLSGLAEKYVGQLGSWLMFASVFINSLGALIAYTNGSGEILSSFLGIPPALGSLMFFIPSVVVIWFGLKVTGVAEKFISFGMVLLILILVLATIFGPGLKNENLLFMNWQFAIPVFSLAIFSFIAQYTVPELARGYRNNQVHNLPKAIITGMLFTGILLAVVPMAALGLTGPEKVTEVVTVAWGNALGQWAFFTANSFALLAMLTSFWAIGESLLTNIVDRFKFPSEWDIKYRILSLAIVAIPPFALAYSGLVGFVDALYFAGAFAGAIMSIVPVMMLNRSRKVAEREPEWTVGKLGHPVIQALLIILFVGAGIYAILDFFQLLPGSW
>NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein
MAQTIPEMLKKGATAGERLLFRTLKDYLPEDYIVYYEPDIQGWRPDFVIIGPDLGLVVLEVKDYTRGTLDRVNPDQWRIQASSGEFLSVKSPIKQAREYAFRIANHLKRDVGLLEEEGKHRMQLKFPYGYGAVLTRLSQEQMEVDGLYTVMNPKLVLTRDEIDPKHERFSAILLRQKLHRMFTVSYTMTKRLNSLDIQRIRFHLFPEVRIGARIRKVSEQEQILLSLDDVETMDLYQESLAKQIGDKHRLIRGVAGSGKTLILASRACLLAKEHPDWKILVLCYNISLSRNIRQMINSKVNQPVSLFDFRREEEGEPFNKDQELGNIQVYHFHEWLTEELKLTEGQIPDIITASNGNQRSLPVYDAILIDEGQDFHPEWLALTSKVLNPKTQSYLIVEDRAQNIYSRKRSYRQDTGLDFRGRSRILTVNYRNTAPIVRFSWDFYKAHSSEKMTVEKTSVEDVEIIAPQSSLRQGPEPEVRRFGSLQEEMVFVGEKIKTLHREEGIPYSEMLILYRVRRFQKNETIGVIQNALLEHGVPFVWFAKDKHTKRKFDPNERGVKISTIDSSKGLDFQVVFVVEVHRLPFPLEKDRSREVSLLYIAMTRAKQHLFITYSGDSEFTGYFDEVAQLSIKGGNDDAFSKGNPTMPYPTG
>NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase
MMHSVKVIQRCRTPRGELQLQQRGEEFEIISNGCFLMSTVNGESEQLLVRLAIQDSAAPRRILIGGLGVGYSLGEALRFQEVEQVTVVEIEEQVIQWNRHYLRSYSGDGLDHPRTRVVHGDIKNWLEKSREKFDVVCMDTDNGPDWTVFEGNKALYGEWGLRLIHNRLSENGVASFWSASASSKFSNRLKSVFASVKEIPVPVEKGEPDYIYLCHRR
>NZ_CP048104.1|WP_173221092.1|1048913_1049810_+|hypothetical-protein
MNWIWLGRSVLPREVEQTLNRNFPGANWSIGWPERKKWQGDYYYCFYRKRGTPVVIRRDGKILTHPKSRWHVMAKNNEASTFSVTIRGIAATIVGFILTFSILGLVIAFMQHNPEKEIVSYFHDGAFALSLVYILLQIPLLTVLFRPANWNWLELAKHRWLLGINLSLLLLTSPFMLFAGDYYTSYTKEGIIHSRFAELGDYRIIPWQDMEKVYLTVEWFDEDLNLVLRSQEDNGTRWLWKTDDQEEAQELLTLLQTWELPPEKLQVEHFEGRELFHISEIFGDDIRQYFYKMAGGKE

Crispr_ID: NZ_CP048104_1

• CRISPR_ID: NZ_CP048104_1
• CRISPR_location: 1037287-1037584
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP048104_1

Consensus_repeat	Method
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRISPRCasFinder
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRT
GTTTCAATACCTCATAGGTAAGATCAAAAC	PILER-CR

spacers of NZ_CP048104_1

>1.1|1037317|39|NZ_CP048104|CRISPRCasFinder,CRT
GGTGATGAAACCCGCTCGAGAGGCAAAGCAACCACCTAA
>1.2|1037386|34|NZ_CP048104|CRISPRCasFinder,CRT,PILER-CR
TCTCCACATGGTAGGAAGGCGACGGGTTGAAATG
>1.3|1037450|36|NZ_CP048104|CRISPRCasFinder,CRT,PILER-CR
AGGCCTACCCCTTCAACTTGTTTTAGTCCAATGCCG
>1.4|1037516|38|NZ_CP048104|CRISPRCasFinder,CRT,PILER-CR
TCTTCCTCCGACAGTTTCTTAATCGGTGGATAGTGGAT

CRISPR arrays and Neighbor proteins around NZ_CP048104_1

CRISPR arrays

The CRISPR arrays of NZ_CP048104_1

>merge|NZ_CP048104|1|1037287-1037584|CRISPRCasFinder,CRT,PILER-CR
TTTTTGTTTTCTCATAGGTAAGATCAAAACGGTGATGAAACCCGCTCGAGAGGCAAAGCAACCACCTAAGTTTCAATACCTCATAGGTAAGATCAAAACTCTCCACATGGTAGGAAGGCGACGGGTTGAAATGGTTTCAATACCTCATAGGTAAGATCAAAACAGGCCTACCCCTTCAACTTGTTTTAGTCCAATGCCGGTTTCAATACCTCATAGGTAAGATCAAAACTCTTCCTCCGACAGTTTCTTAATCGGTGGATAGTGGATGTTTCAATACCTCATAGGTAAGATCAAAACC

>NZ_CP048104|1|1|1037287-1037584|CRISPRCasFinder
TTTTTGTTTTCTCATAGGTAAGATCAAAAC	GGTGATGAAACCCGCTCGAGAGGCAAAGCAACCACCTAA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTCCACATGGTAGGAAGGCGACGGGTTGAAATG
GTTTCAATACCTCATAGGTAAGATCAAAAC	AGGCCTACCCCTTCAACTTGTTTTAGTCCAATGCCG
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTTCCTCCGACAGTTTCTTAATCGGTGGATAGTGGAT
GTTTCAATACCTCATAGGTAAGATCAAAACC

>NZ_CP048104|1|1|1037287-1037583|CRT
TTTTTGTTTTCTCATAGGTAAGATCAAAAC	GGTGATGAAACCCGCTCGAGAGGCAAAGCAACCACCTAA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTCCACATGGTAGGAAGGCGACGGGTTGAAATG
GTTTCAATACCTCATAGGTAAGATCAAAAC	AGGCCTACCCCTTCAACTTGTTTTAGTCCAATGCCG
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTTCCTCCGACAGTTTCTTAATCGGTGGATAGTGGAT
GTTTCAATACCTCATAGGTAAGATCAAAAC

>NZ_CP048104|1|1|1037356-1037583|PILER-CR
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTCCACATGGTAGGAAGGCGACGGGTTGAAATG
GTTTCAATACCTCATAGGTAAGATCAAAAC	AGGCCTACCCCTTCAACTTGTTTTAGTCCAATGCCG
GTTTCAATACCTCATAGGTAAGATCAAAAC	TCTTCCTCCGACAGTTTCTTAATCGGTGGATAGTGGAT
GTTTCAATACCTCATAGGTAAGATCAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein	unknown	unknown	gnl|CDD|225279
NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase	unknown	unknown	gnl|CDD|223498
NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223943
NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein	unknown	unknown	gnl|CDD|378910
NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit	unknown	unknown	gnl|CDD|223564
NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl|CDD|349967
NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein	unknown	unknown	gnl|CDD|226481
NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase	unknown	unknown	gnl|CDD|225357
NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein	unknown	unknown	gnl|CDD|238206
NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein	unknown	unknown	gnl|CDD|377252
NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein	unknown	unknown	gnl|CDD|378910
NZ_CP048104.1|WP_173221092.1|1048913_1049810_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173218907.1|1035368_1035542_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221077.1|1039586_1039883_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein	unknown	unknown	gnl|CDD|273257
NZ_CP048104.1|WP_173221071.1|1035753_1036068_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter	unknown	unknown	gnl|CDD|223551
NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein	unknown	unknown	gnl|CDD|376356
NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease	unknown	unknown	gnl|CDD|223884

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein	gnl|CDD|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	2.54025e-87
NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	6.81333e-30
NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase	gnl|CDD|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	9.69508e-18
NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein	gnl|CDD|378910	pfam12671, Amidase_6, Putative amidase domain.	1.08732e-46
NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit	gnl|CDD|223564	COG0490, COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism].	2.42731e-55
NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl|CDD|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	4.63765e-94
NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein	gnl|CDD|226481	COG3972, COG3972, Superfamily I DNA and RNA helicases [General function prediction only].	1.87247e-19
NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	5.93549e-18
NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase	gnl|CDD|225357	COG2766, PrkA, Putative Ser protein kinase [Signal transduction mechanisms].	0
NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein	gnl|CDD|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	6.14338e-26
NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein	gnl|CDD|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	3.03674e-72
NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein	gnl|CDD|378910	pfam12671, Amidase_6, Putative amidase domain.	5.61067e-37
NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein	gnl|CDD|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	1.67526e-106
NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter	gnl|CDD|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.3245e-50
NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein	gnl|CDD|376356	pfam00586, AIRS, AIR synthase related protein, N-terminal domain. This family includes Hydrogen expression/formation protein HypE, AIR synthases EC:6.3.3.1, FGAM synthase EC:6.3.5.3 and selenide, water dikinase EC:2.7.9.3. The N-terminal domain of AIR synthase forms the dimer interface of the protein, and is suggested as a putative ATP binding domain.	6.75372e-05
NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease	gnl|CDD|223884	COG0814, SdaC, Amino acid permeases [Amino acid transport and metabolism].	5.12421e-49

Protein sequences

>NZ_CP048104.1|WP_173221073.1|1036584_1037175_+|GrpB-family-protein
MSSMQDGFNSKPTSDEDLQKVRMGELKPHNAPITLVEYDSRWPELFEGEANRVRSALGNKALQVEHVGSTSVPGLCAKPIIDMILVVADSADEPSYVPTLEAAGYTLWIREPEWFEHRLLKGPDIDINLHVFSAGTSEIERMLRFRDWLRANDTDRDNYARAKRSLARRVWRHVQHYADAKTAIIQEIMDRANAAE
>NZ_CP048104.1|WP_173221071.1|1035753_1036068_+|hypothetical-protein
MEKNGIDQHKDGYLQYVQQEAKEIGKVFILDTGEGNDLEDPVTGWYVEDLSGWLIDSRLKEQFLIDLEESKHWDTFDGYYVFVEWKLKDNNEIEIKFVKYPLYE
>NZ_CP048104.1|WP_173218907.1|1035368_1035542_+|hypothetical-protein
MDMDSKKLQFGNATVIVHSPLANMTEEERKAWYDQQWERKNPLMYEIARAIFDCQRD
>NZ_CP048104.1|WP_173221069.1|1033479_1035033_-|recombinase-family-protein
MNRPNGLDCFIYLRKSRTDIEEEKKALKEGFSFDVLERHRKQLLELAKQEQHNILDIYEEVVSGEHLLDRPQIQQMLKLVEQGHCAGVLVMDLDRLGRGDMYDMGMIYRSFQYSETLIVTPTEVIDPNSDGAELLFGVKSILSREELKGITKRLQRGRQISAREGKSISKKPPYGYIRDETLKLHPDPETSWVVKNIFERVVEGAGRIQIAQELDEMGVTSPRGEGPWSPSTIAAIIKNEVYMGHIIWGKIQYIKRGGGKYTRKRVPPDQWHRHDHAHEPLVSEELFKEANLALSGRWRPPTKKANKLTNPLAGILQCERCGRAIRYFPRKDRPNDDMRCIWPGCRGKQRGCSFPFVEKAILDGIRYLLQQYEAIDEVNREKKDNVISLKEKGSENLKKELDDLNTQRNRLHDFLEQGVYDIATFRERQQVVVTRIRKAEDQLKEIEREIEKEKIRVKQQKEVIPKLWNVIEAYQKTHDPLKKNRLLKTVLEKATYFRDPTWTEPGKIRIHVYQRIW
>NZ_CP048104.1|WP_173225228.1|1030489_1032388_+|PrkA-family-serine-protein-kinase
MDILSRIAQQRKKEEELAWEGSFREYLQMVQKRPELAQTAHSRVYRMIADSGIEKDEQGNISYLFFSRELFGLDQAIERLVEEYFHSAARRLDVRKRILLLMGPVSGGKSTIVTLLKRGLERYSRTEAGALYGIKGCPMQEDPLHLIPYNMREELEKEWGVKIEGNLCPSCRMRLEKEYNGRVEDVRIERVLISEDNRVGIGTFSPSDPKSQDIADLTGSIDFATITEYGSESDPRAYRFDGELNKANRGLMEFQEMLKCDEKFLWNLLSLTQEGNFKAGRFALISADELIMAHSNEAEYKSFISNKKNEALHSRIIVMPIPYNLKVSEEERIYEKLVRQSDLGHVHIAPHALATASVFSILTRLKPSKKQGLDLIKKMRLYDGKSVEGYKESDVGELRNEHLDEGMSGIDPRYVINRISSALIRSQADCINALDILRSIKDGLDQHPSITQEERERYLNFISIARKEFDELAKKEVQKAFVYSYEESAKTLLDNYLDNVEAFCNWNKLQDPLTGEELDPDEKLMRSIEEQIGISENAKKAFREEILIRISAYARKGKRFDYNSHDRLREAIQKKLFADLKDVVKITTSTKTPDENQLKKVNEVTATLIDKYGYCPTCANDLLRYIGSLLNR
>NZ_CP048104.1|WP_173221067.1|1028501_1029962_-|amidase-domain-containing-protein
MIELRKLFKIRFVLVALLGLTLVVSGCSSDTAKVADSKEVARTPEEDSSQDEADSIFDEEISKEISYYDESSKSKKEIEKNNQPAIQIVKQTSQKNQVKVEADLDKAQFRDMVRATAADLQSLKPHERKQVINLVKDINQYENKKINNEIKKLKSKADKGTLSGAEKAKLLSLLPIDKKGVKVKPEQKINPDQVPPASDLKDKKPGNSNPDKLLPEKPGKEEQTQPEKETPKPGNKTPQPGDKEDEPENEQTEPGENQESGQDNENQQENEEQDQNDGNDQNEQEPQQPDNENTEEEEKPESKDPGKDKDQQKDTEKSMVEKNGYDRAKARDYAYKWWNKRNNEEYGYYSKAMGGCYSCWYDCTNFTSQALKAGGLKEWKSDPWWYYSDKKPSYSWGVANSQYKHLEQRAKPAKSLSEVKVGDIVHGDFDHDQKIDHSAIVTKIQNGEIYLTYHTTDKKDVPLSYWFYYDYDVYVWKMGTANNQAR
>NZ_CP048104.1|WP_173221065.1|1027741_1028461_+|HAD-family-hydrolase
MKVKACCFDLDGTLLPMELDDFIAEYFRALVPYVAHLMPPKQFFVYMGDAMKRMIGDDDPNRTNEEVFMERFLSRSGLEQDKVWPLLERFYEEEFPKLRKYVTPTPVARQVVQAAMEQGMDVIVATNPVFPRAAIEERLRWAGVEDLIKWVTVYEESHFCKPHVQYYQEVAGRLGVLPEECVMIGNDMQEDMVAETIGMKTYFLKDCRIDRGEPVYHPNQEGNLNDLLEDIRNQRGVFQ
>NZ_CP048104.1|WP_173221063.1|1027250_1027715_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MSFHICLVEPEIPNNTGNIARTCAVTGSILHLIRPLGFSTDDKYLKRAGMDYWHHVDVRYYDSFDEFQSSFPKGRFFCATTKAQKHYSSFEFREGDIFVFGKETAGLPSEILETYRETCMRIPMKPDIRSLNLGNSAAIVIYEALRQTGYPDLV
>NZ_CP048104.1|WP_173221061.1|1026164_1027013_-|DegV-family-protein
MTKIALVTDSSCDLSSDLLSKFNIEVVPLRIIYAQTEYRDQVDITPNEVYDRLDEEVPTTSMPSPQDILETFEKLADTGYSHCIVISLSSGLSGTYQAFQMIAQNFDRMKIDIIDSKGLSWILGFLVLEAAQMIQEQFDYHEILERIKRIRQKIKGFFIVDTLEYLKKGGRIGKVAATLGSMLNLKPIITTDDQGLFTPYQLARGKKQAIKKMVEPLLKQLESTKASIAIIQGRAEVEAEALRLRLKDLDRIGNLYVSPVSPALVVHTGPGLIGIVINPEHS
>NZ_CP048104.1|WP_173225225.1|1025123_1026101_+|amidase-domain-containing-protein
MMWRESLKGTVRMKTRSWRQPVASWFRGQSQVWVEGGIDRLFTWVQHQDADWVIKEQKRWERVRDLQEERKMKRLKGETRIRVIQEERLENGDIMMKVWVYQRYLYSIKERFFEQEESNGFSIQLAEGGAGWFIMKCKVEPEMNTEVERDWSYYQPPDFGTRSGSSYNRMKAVQYAETWWNGANPRYQKFEVDCTNYVSQCLHAGGIPMEYSYQRARGWWYRGSRENWSYSWAVAHSLKNYLDKGGVHRAEIVDSPRQLQPGDIICYDWDGNGRWQHNTVVTTLDASGEPLVNAHTVNSRHRYWDYRDSHGWTPQVQYRFYHIPD
>NZ_CP048104.1|WP_173221075.1|1038798_1039266_+|SMI1/KNR4-family-protein
MDKQITWEYKRMSVTDEVLREQEKLLGIRLPDDFREVFIENHGAGPVPECYYASNGNGRNFGFLLALDKDEDGEVEFTDANSPYMKREHNMPNEVVIFSIDPAGNFLCFDYDQLNDGYPSIIFWDHEVEGGAVKKICNTFTELLQMLHEVGDEES
>NZ_CP048104.1|WP_173221077.1|1039586_1039883_+|hypothetical-protein
MFAYQYIMVDWLHNYGDEYPIRIYSEIDKNGFETRKVEIFPNNQIGYAFDSIEFGGTGLGMEPVLDLNEIAADPYETFIPKEISKEEFEKIWSMYIKD
>NZ_CP048104.1|WP_173221079.1|1040824_1042033_+|cation:proton-antiporter
MDTLIFEVGLAIALIAVVGVLSTKLRFSVIPFYILVGMVVGPHAPHFGIIDLRFIESSVFIDFMGRLGVLFLLFYLGLEFSVGRLIKSGKSILIGGSFYVVLNFVSGLLLGWMMDYPLKETMVICGIMTSSSTAIVAKVLVDLKRTANPETEIIMGMIMFDDLFIAVHISILSGLVLSGASSWVGVLFTSLTALIFILLFIVIGRKLMPLIDKVLNVRSSELFLLLIIASLFLVSGFSETLHVAEAIGALLIGLVLAESVHAKRIEQLVLPFRDLFGAVFFFSFGLTIDPTSLGGAVWAALVGVLLTIIGNVLSGFFAGRASGLSGKSTANIGFTLVSRGEFSIIMANIGKEGNLMPVIQSFAVLYVLILAVIGPFMAKESKTIYGLCQKMMGRFRKRSTGT
>NZ_CP048104.1|WP_173221081.1|1042087_1042579_-|cation:proton-antiporter-regulatory-subunit
MDIRETDLPGIGRKYQVVTRTGEKAVVIIHDDGRREMYHFDPNDPDESISVVTLDDEEARQLAGIIGGMNYQPKALENIEIALEDLIIEWYKISPQAKCNGVTIGKLMVRQKTGATIIALIEKNQRKTINPGPDHVLASGTTLVIAGERKQINQLKQILSDGG
>NZ_CP048104.1|WP_173221083.1|1043039_1043819_+|hypothetical-protein
MGWMPLGQKGFSLRKVRDLTVMDFQDSISLVIACDSLGGIGNKPWDQVQVPPETVGIFGVRVPLFEVIASGGVPIHVSDCLAVEMEDTGRRIIEGIRSYCAEAGVIEENQFNGSTEENVLTLQTGIGIMVTGWVEQGGFFPGCSEAGDVILCAGIPKSGPQFQISLEDPELLSLQELIRLRKDQGVGDLLPVGSKGVKYEAEQLAESAGLSVQLKEDVAVDLHRSGGPATCAVFSCKPGDMDRLANKLTTPLHQVGYLF
>NZ_CP048104.1|WP_173221085.1|1043909_1044809_-|acetamidase/formamidase-family-protein
MKQISRKHFIGSFSPSHSPMETVPLRESFWVETHDCYGGKIRTEQDLRPQINISPLNPSTGPIAVEGVRKGDIIRVSIEEIQLDDQGVMVMMPGLGPLGDMVQETHTKIIPIRDGTVYFSDNIHFPVQPMIGVLGVAPETGEISTATPGNHGGNMDTKEITTGSHVYFPVFIDGANLALGDLHAAMGDGEMDGTGIEIAGKVRLSVSKVPDFDLSMPLVETKQEYLIVSSQKTYDKAIQEGMKQAVSLLQYRLDLSFTEAYRLLSATGDLRISQIVNPCVTVKIAIPKSLFPKQTLFND
>NZ_CP048104.1|WP_173221087.1|1044821_1046054_-|amino-acid-permease
MKKSKNHANTPSSSLRMEKISFWEGVALIVGANIGAGILSLAYGAKNAGWPVLVLWVAVAGIFTTISMLYVAETTLRTEKPLQLSGLAEKYVGQLGSWLMFASVFINSLGALIAYTNGSGEILSSFLGIPPALGSLMFFIPSVVVIWFGLKVTGVAEKFISFGMVLLILILVLATIFGPGLKNENLLFMNWQFAIPVFSLAIFSFIAQYTVPELARGYRNNQVHNLPKAIITGMLFTGILLAVVPMAALGLTGPEKVTEVVTVAWGNALGQWAFFTANSFALLAMLTSFWAIGESLLTNIVDRFKFPSEWDIKYRILSLAIVAIPPFALAYSGLVGFVDALYFAGAFAGAIMSIVPVMMLNRSRKVAEREPEWTVGKLGHPVIQALLIILFVGAGIYAILDFFQLLPGSW
>NZ_CP048104.1|WP_173221089.1|1046311_1048267_+|NERD-domain-containing-protein
MAQTIPEMLKKGATAGERLLFRTLKDYLPEDYIVYYEPDIQGWRPDFVIIGPDLGLVVLEVKDYTRGTLDRVNPDQWRIQASSGEFLSVKSPIKQAREYAFRIANHLKRDVGLLEEEGKHRMQLKFPYGYGAVLTRLSQEQMEVDGLYTVMNPKLVLTRDEIDPKHERFSAILLRQKLHRMFTVSYTMTKRLNSLDIQRIRFHLFPEVRIGARIRKVSEQEQILLSLDDVETMDLYQESLAKQIGDKHRLIRGVAGSGKTLILASRACLLAKEHPDWKILVLCYNISLSRNIRQMINSKVNQPVSLFDFRREEEGEPFNKDQELGNIQVYHFHEWLTEELKLTEGQIPDIITASNGNQRSLPVYDAILIDEGQDFHPEWLALTSKVLNPKTQSYLIVEDRAQNIYSRKRSYRQDTGLDFRGRSRILTVNYRNTAPIVRFSWDFYKAHSSEKMTVEKTSVEDVEIIAPQSSLRQGPEPEVRRFGSLQEEMVFVGEKIKTLHREEGIPYSEMLILYRVRRFQKNETIGVIQNALLEHGVPFVWFAKDKHTKRKFDPNERGVKISTIDSSKGLDFQVVFVVEVHRLPFPLEKDRSREVSLLYIAMTRAKQHLFITYSGDSEFTGYFDEVAQLSIKGGNDDAFSKGNPTMPYPTG
>NZ_CP048104.1|WP_173221091.1|1048217_1048871_+|spermine/spermidine-synthase
MMHSVKVIQRCRTPRGELQLQQRGEEFEIISNGCFLMSTVNGESEQLLVRLAIQDSAAPRRILIGGLGVGYSLGEALRFQEVEQVTVVEIEEQVIQWNRHYLRSYSGDGLDHPRTRVVHGDIKNWLEKSREKFDVVCMDTDNGPDWTVFEGNKALYGEWGLRLIHNRLSENGVASFWSASASSKFSNRLKSVFASVKEIPVPVEKGEPDYIYLCHRR
>NZ_CP048104.1|WP_173221092.1|1048913_1049810_+|hypothetical-protein
MNWIWLGRSVLPREVEQTLNRNFPGANWSIGWPERKKWQGDYYYCFYRKRGTPVVIRRDGKILTHPKSRWHVMAKNNEASTFSVTIRGIAATIVGFILTFSILGLVIAFMQHNPEKEIVSYFHDGAFALSLVYILLQIPLLTVLFRPANWNWLELAKHRWLLGINLSLLLLTSPFMLFAGDYYTSYTKEGIIHSRFAELGDYRIIPWQDMEKVYLTVEWFDEDLNLVLRSQEDNGTRWLWKTDDQEEAQELLTLLQTWELPPEKLQVEHFEGRELFHISEIFGDDIRQYFYKMAGGKE

Crispr_ID: NZ_CP048104_3

• CRISPR_ID: NZ_CP048104_3
• CRISPR_location: 1068207-1068637
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 6 spacers

Consensus repeat of NZ_CP048104_3

Consensus_repeat	Method
GTTTCAATTCCTCATAGGTAAGATCGAAAC	PILER-CR
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CRT

spacers of NZ_CP048104_3

>3.1|1068237|36|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
GCAAGATCAAATTGAACCTAGAAAAGAAAAACCGAT
>3.2|1068303|36|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
CGTTTTTCGTAATTGTGGCCATCATGATCCAACTTT
>3.3|1068369|36|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
TACAAGATGGAGCGTACAGGATTAAAGGTGAATCGT
>3.4|1068435|38|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
GGTAGGGATAAAGAAGAGATGACAGCAACCGAATTCGC
>3.5|1068503|38|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
ACAAAAACACTTTGGTTGAAAAGTTGCGTGCTCTGTAC
>3.6|1068571|36|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
CAAGGCATGGGAAAAACTCTCTCGCCGGAAAGTGTT

CRISPR arrays and Neighbor proteins around NZ_CP048104_3

CRISPR arrays

The CRISPR arrays of NZ_CP048104_3

>merge|NZ_CP048104|3|1068207-1068637|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCCTCATAGGTAAGATCGAAACGCAAGATCAAATTGAACCTAGAAAAGAAAAACCGATGTTTCAATTCCTCATAGGTAAGATCGAAACCGTTTTTCGTAATTGTGGCCATCATGATCCAACTTTGTTTCAATTCCTTATAGGTAAGATCGAAACTACAAGATGGAGCGTACAGGATTAAAGGTGAATCGTGTTTCAATTCCTTATAGGTAAGATCGAAATGGTAGGGATAAAGAAGAGATGACAGCAACCGAATTCGCGTTTCAATTCCTCATAGGTAAGATCGAAACACAAAAACACTTTGGTTGAAAAGTTGCGTGCTCTGTACGTTTCAATTCCTCATAGGTAAGATCGAAACCAAGGCATGGGAAAAACTCTCTCGCCGGAAAGTGTTGTTTCAATTCCTCATAGGTAAGATCGAAACC

>NZ_CP048104|3|3|1068207-1068636|PILER-CR
GTTTCAATCCCTCATAGGTAAGATCGAAAC	GCAAGATCAAATTGAACCTAGAAAAGAAAAACCGAT
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CGTTTTTCGTAATTGTGGCCATCATGATCCAACTTT
GTTTCAATTCCTTATAGGTAAGATCGAAAC	TACAAGATGGAGCGTACAGGATTAAAGGTGAATCGT
GTTTCAATTCCTTATAGGTAAGATCGAAAT	GGTAGGGATAAAGAAGAGATGACAGCAACCGAATTCGC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	ACAAAAACACTTTGGTTGAAAAGTTGCGTGCTCTGTAC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CAAGGCATGGGAAAAACTCTCTCGCCGGAAAGTGTT
GTTTCAATTCCTCATAGGTAAGATCGAAAC

>NZ_CP048104|3|3|1068207-1068637|CRISPRCasFinder
GTTTCAATCCCTCATAGGTAAGATCGAAAC	GCAAGATCAAATTGAACCTAGAAAAGAAAAACCGAT
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CGTTTTTCGTAATTGTGGCCATCATGATCCAACTTT
GTTTCAATTCCTTATAGGTAAGATCGAAAC	TACAAGATGGAGCGTACAGGATTAAAGGTGAATCGT
GTTTCAATTCCTTATAGGTAAGATCGAAAT	GGTAGGGATAAAGAAGAGATGACAGCAACCGAATTCGC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	ACAAAAACACTTTGGTTGAAAAGTTGCGTGCTCTGTAC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CAAGGCATGGGAAAAACTCTCTCGCCGGAAAGTGTT
GTTTCAATTCCTCATAGGTAAGATCGAAACC

>NZ_CP048104|3|2|1068207-1068636|CRT
GTTTCAATCCCTCATAGGTAAGATCGAAAC	GCAAGATCAAATTGAACCTAGAAAAGAAAAACCGAT
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CGTTTTTCGTAATTGTGGCCATCATGATCCAACTTT
GTTTCAATTCCTTATAGGTAAGATCGAAAC	TACAAGATGGAGCGTACAGGATTAAAGGTGAATCGT
GTTTCAATTCCTTATAGGTAAGATCGAAAT	GGTAGGGATAAAGAAGAGATGACAGCAACCGAATTCGC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	ACAAAAACACTTTGGTTGAAAAGTTGCGTGCTCTGTAC
GTTTCAATTCCTCATAGGTAAGATCGAAAC	CAAGGCATGGGAAAAACTCTCTCGCCGGAAAGTGTT
GTTTCAATTCCTCATAGGTAAGATCGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293841
NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein	unknown	unknown	gnl|CDD|377285
NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl|CDD|235465
NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP048104.1|WP_173221124.1|1071365_1071785_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain	unknown	unknown	gnl|CDD|333735
NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein	unknown	unknown	gnl|CDD|214861
NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224196
NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein	unknown	unknown	gnl|CDD|377846
NZ_CP048104.1|WP_173221104.1|1056460_1058362_+|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|376899
NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221108.1|1059447_1060269_+|ABC-transporter-permease	unknown	unknown	unknown
NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase	unknown	unknown	gnl|CDD|274273
NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein	unknown	unknown	gnl|CDD|377285
NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase	gnl|CDD|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.07705e-46
NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein	gnl|CDD|377285	pfam04293, SpoVR, SpoVR like protein. Bacillus subtilis stage V sporulation protein R is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR.	6.92725e-173
NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	1.00906e-97
NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	5.67586e-92
NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl|CDD|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	8.61834e-170
NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.34184e-30
NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	4.76648e-93
NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.16751e-07
NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain	gnl|CDD|333735	NF012201, WIAG-tail, WIAG-tail domain. This 80-amino acid domain occurs in proteins in a single copy at the C-terminus. In most proteins, the domain immediately follows a long, variable run of tandem 10-amino acid repeats. The domain is named for its C-terminal motif, WIAxGx, hence the name WIAG-tail.	2.06249e-12
NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein	gnl|CDD|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.03968e-54
NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.00144248
NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein	gnl|CDD|377846	pfam07485, DUF1529, Domain of Unknown Function (DUF1259). This family is the lppY/lpqO homolog family.	2.229e-47
NZ_CP048104.1|WP_173221104.1|1056460_1058362_+|FtsX-like-permease-family-protein	gnl|CDD|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	0.00199114
NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	4.91639e-90
NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	9.67847e-13
NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase	gnl|CDD|274273	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.9474e-98
NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein	gnl|CDD|377285	pfam04293, SpoVR, SpoVR like protein. Bacillus subtilis stage V sporulation protein R is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR.	2.33134e-26
NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	2.59708e-87

Protein sequences

>NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein
MTVALYCRVSTDEQVQQGFSIDNQKERLQAFALSQGWTDYRFYIDDGYTGTNMDRPGLKRMIQHAEDGTIRTIVVYRLDRLGRRQKDVLFLLEDVFEKSNVAFKSATEPFDTATPLGKAMIGILAVFAQLERDTIVERTTAGRRQRIRSGKWYGGRVPFGYQWNSTTQTLEVVPEESTLVKEAFSMYLQGHSSSYIADWLTSRSTARFFDHSVIRTMLQRPIYTGHMNNAGKLVEGQHEGIIDGETYERVQQELHKRQTGRPPVGEYLLSGILRCGICGGPVIHVWASGKRYEYYACKAQHVRQRNKGHHCSLGYTRKEKLDSWVAERLKQISLNPEQVEVQLKTLTTMQQEQRDRTAELEQRLENINHRLERWYDAFEQGLLNPAQLKKRIDSLEEERKTVMIRLDELDHTPKEQWAEGVIQTLETIGEAWDSMNFSEQKMVLRAALDHIVLFPDREPKLIWNV
>NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein
MADHLQELERSVHEITEIARGFGLDFFPMRYEICPADILYTFGAYGMPTRFSHWSFGKGNHRKYEKPLNVPYQLWLSIREQDNMIQCGS
>NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase
MWTLIIGIPFAVIILSISLMGWRYVKFRGKVPRPRARGIRRRFHPEELSDDDISLAWIGHSTVYINLYGIKILTDPVFSHRVGVSLFPGITVGLKRYTPPAVSLEEVKGVDLILLSHAHLDHLDMPSLKALADSGTQVITAKNISHLLKKLSFGRIDELSEGETIDWGKGLKVTSIPVKHWGSRFPWNKEYGWTGYELEIRGKRVVFAGDTAYTPSFRKLGEAGAVDVMIMPIGAYSPDEFQKSHCTPEQAWEMTVDSGAKKMVPIHWNTFVLSREPIEEPMERLLKAAGEQADRIVIREQGEIWRLSANTEISLSEPIGERKSVSLYQKKEVSSRVNPSAT
>NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein
MSSLQRLCEQFARIVGGEASVLNGVCFIQKFRRFPITILGRRTRSPLVNPTFFSFESIDKKGRALNLGETVILQNEINPFISVLRKEGIKVTALHNHWLFENPRLFYIHFESVENPIIFARKVARALKVLK
>NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase
MEKKVIVIGGGLGGLSAAVCLAVEGYSVTVYEQGSQVGGKLNKQTGKGYSFDTGPSDLTMPWVLEQLFTRAGKKMDDYFSLIRIKPQWKAFFSDETTLELTSDLPFLFQQMKEQFDTEATALLQYLQHCSKMYELTQKSYYKKSLAGSEEMRKMHSMKEWMSLSSMKSVHQKTSQYIQSPHLKQLFDYLSISIGSSPHQAPVFLSLMTHSLLGMGSFYAQGGMYTIAEGIERLLQELQVKVHTNMKVSAIQYDNQERVKGILLQDGTIVPADIVICNRDPVTAYHSLLSNHSKVESAIRDLNKYPPGLSGMVLLLGVKGTYDHLQHRNIFFSANPQEEYEQLFKEGKPATDPTISVHLSCKSDPGQAPKKKSNMVVLTHVPPLKPGESWEPYRRQYRDRIIEKLEQRGITNLEKNIEIETQFIPDDFHHLYGANGGSLYGVAADRKKNNGFKIPCRSTLLQNLYFVGGSIHPGGSIPMASLSGQLAADLIIKDHAIIPVPTA
>NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase
MTSNNYPTDKRKSEHIDIVLNQKVTGTNITTGFEAYQFRHNALPEINFDDVSLYTTFLGKPLKAPFLVSSMTGGTDQAWKINKHLAVAAEEQGWAMGLGSVRAAIEQPSTAYTFQLREYAPTIPILANLGAAQLNYGYGVNECRQVVELTQADALIFHLNSLQEVFQPEGDTRFRSLIRQIAEVCKKLDVPVGVKEVGWGIDGKVAKLLFEAGIHFIDVAGAGGTSWSQVEKYRSQHKDPLRYQAAEAFTDWGIPTAECVIDVRQRNPQGTVISSGGLYTGVEGAKAIALGADLAGYGRSLLTAATQSTPEQLRFVMQRIELECKIAMFGIGAATLSDLKRTDRIHHIHTRTTFRT
>NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease
MKELIISEWERAWGRKKTQMLLIVYPVLVFLMEVFMLQFGVGFYDMEHEVALHALNFPLFSLRDLSLLLVFVIAPMLWVDSFSGEYSTGAYRMVLIRPYSKGKLLAAKWVSQAALTGILLLIPFVMSQIVGWINLPNPSVTTFFYEGAERYDMGEALLYQLCFYGWIFLILLVCQSVCALLGTWMPNPILSFLAYAGGLIGSIYLSDSFIILFGHTDEVFRLMAGKAEVSVYYVLFGTLVVSLVSIYGSWKKKDWVK
>NZ_CP048104.1|WP_173221108.1|1059447_1060269_+|ABC-transporter-permease
MLALIRSEWERLWCRKLTWLLFGLIPVMTIAGARYMKGEHAHLSPDKPQYAVFHNFPVLALAEMLITAVNLILILWLIVSMTQEYRTGQLRMVMLRSYSPVAIFSAKWLTVIAALFLYLAVFFMVSYITGWFLLPKTESLTLFYHPGTATGWEAFWYNLQYYGMAFITLIVMSSIIMCIAVASPTSTTAIGISLGFVLVSFGYIHILQMFTMNYPVHPKWYYLSLVQIQYEGITLLLAVKPMLGKWISMVLATYGGVFMGTSWLLVRRQDRFM
>NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein
MDTDVLLEVKNVTKKVRGRTLLHDVSFGVRKGEICGFLGPNGAGKTTMIRVMTGLIAPSQGEVRINGISVQQNRQRALSSLGAIVESPLFFPYLSGRKALGNLSRLHPNLSRKEQKKQVEKVLELVGLKDRGNDKVGTYSLGMKQRLGIAQALLGKPEVIILDEPANGLDPIGMRFLRELILKLRDEEGLTFLISSHLLDELQQVCDRLVMIKEGSLVWEGDSDELAGGVTWVFTVGNVDLALQAIGNAYPVKCLDDRQLEIVIEEDQVGHVSRLMMAQGIDVMGIEKRTRRLEDAFVEMMS
>NZ_CP048104.1|WP_173221104.1|1056460_1058362_+|FtsX-like-permease-family-protein
MDFWILAYKNIRYHFRNYLAYFLSSTFAVLLFFLYASLLDHPELPWNKFWGLKLLGIMVIGIVVLFSAWFLHYSHRVFIQARNEEWALLESLGMPRKQRLLLLLMENGLMGMGAIAVGLFLGTVLMKLFYLFISYMLKLEVPITPRFSLSVTVWTVIIFGLMFSVISWREEKYMRSTSVKELLQNREGWGKGIPQPSYIVKGLALVTLTAGYVWIGRVESLWEALYWFVPSILLILTGTYLFYREAMIDGIQFLKRRRAFYYKGVYLLFFSRLSEHWGDHVRLLFMVTVMNTMVLSGVGIFFSAFQEVDHMAVRQNPFSVSLVGEPETLPLERVEEILRKEELRVIRKEEIPVLKASQHDRSDSELAVVALSDFNRLLIRFTQIAPLKVKAGKGIYIFPYDGYQAANREATFSLGIGGQTENVSVSQQMNYRVFNEHPLTGGVMILDDDTFSTWQKRYGKKAGTDIHGWVLADWKESGAAVEQMRQELGKEERKALADTPVEARFFLYQLFSPTLFVSLFVSILFFLAACSLLYFRVFHHLPREREQMKVLSRMGIPRRDGDRSATLPILFFFFLPLAVSVLHSLAMLNFTEAMVGISVGGHMAGVFAGYGVLYSIYYRMTRNAYLKALNHTS
>NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein
MKDEVLKMIQIECDRVPEAFGGQVSEEEVEKAEGILGVKIQDDYKEFIRRFGAGCVGQAVILGLREAEFFPTPSFIEESLDFRKHLPSAYSKMVVIGVDGAGNPIGFIYPSEMIFVYDHDFGGRYDLANSFEDYILKALNRTLGIHF
>NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase
MSNEKHVVKLLEGRRVYLRPPETEDVPLLYRSFYHPEVRRLTGTTQMLSVEGMENWLEKVVKDESRLFLLIVDQEKDEVMGDIELLDMHQVHRSAWIRIALHREEYFGKGYGTEAMHLMLNHGFHSLNLHRIELEVYDYNHRAIRTYERLGFRREGVRREGLFHNHAYHDVILMGLLAHEYEFPGEVKDYQK
>NZ_CP048104.1|WP_173221124.1|1071365_1071785_-|hypothetical-protein
MKTKLFALGFAFLLAISLFSTSSNVATASEVSTNEYLNETVTFKETVDTPVFTHDEKKGNLQLDTYATYLEDKADFDYFVVTLYEAGSDVTMGNKVALYTNDLDIAAWDVPSGKYYFRFEKPRNGLKLKVKYSVYPYNG
>NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein
MTFSYLRCIAKAFHRMKTDYDLDLGRIYELVINSNPCYAFLLEGNSLIQNKLIIAHVLAHSDFFKNNVRFSNTSRDMVESMAASAERIRRYEMDYGKDQVEAFLDHVLAIQEHIDPGLIRRPRKKEKSSSSDNRHSTPYDDLWALERREEDKNEQKSGTSKVQEKDILLFAMENNPKLQDWQQDILTVMRDEMLYFWPQLETKIMNEGWASYWHIRILREMNLTNEEVLEFAKLNALVTQPSSGSINPYHLGLKIFEDIERRWDHPTEDEQVRFGRKPGQGRQKIFDVREMEMDTSFIRNYLTRELTEEMDLYIFQRKGAEWTVTDKEWQKVREQLIASRVNGGYPYIVVEDGDYQDKGELYLRHRFEEMELDIKYVEKTLPHVHALWGRPVHIETVVENRPVLFTYNGKRCSRRFL
>NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain
MSKVSRKKRPSLRQRTQPTTRMEDEWVLEKIIQKELEDIKKQATLSSEQRSSSENKSTSSPPPAQALTMNRDATNGSKNLQPATTHSSDRVQQVEKIKRNRTQGNGNAFIYTGDLVDESITNEKLANDSIDSSKIQASAVEKEHLRDQSVNSSKLADGSVHATKIAPRAIKEYHLSADSISGDQIQREAIQTEHIKEGGILGNRLSDYSIDGTKIKDHSIQANHLTPKQIQGSHLADQTITASKIESGSIHTNLLANEAVNQAKMAEGAVAAKNLQAGSVTMDKLAEESVSSEKIVPQAIQKNHLDHGIIDSHHLSDHAVTNQKIAPEAVDGTSIKKESITGEHIEQGTIENYHLTHSSVNQEHIAPGSIEAKALQNESIQSKHISHHSVQTHHLGDSVVTGNKIAPNSIQSEHLEMKNIHSFHLADQSVQEQHMAPQSIGSTHFQRDSVLTEHIKEGSILGNRLADYSIDGTKLKNYAIEGHHIAPKQIQGSHLEDQTITASNIETATITSNLLANEAVNRTKLADESVSTDKLQQNAVTSEKMAEGAVTSDQLALQSIQSKHLDHHIIDNHHMMDLVVTSSKLAPESVGSDTIQTEAIQSHHLGQQTIQGEHLADDSIHQDKVAPDAIGSDAVQKQAIHSQHLADNTVQTYHLTDNSVTGEKLADRSVTTSKLCPESVSTDKLIDYSITNSKLGNQVVTSNKLSPESVRGDHIQTDAISAIHIQDEQIHASHLVDRTITSEKLAPQSISEEHIAQESLSSKHIAQDTIGPDHLTMESIQSRHLALDSIQSQHIEEEAITGEHLCPYSITADKLADGTIQSRHLDDEILMARHIGERQVESSHLADSLITSEKLATRSIQGNHIEKEAISDEHLCPYSINADKLADGSIQSRHLNDEILTARHIGESQVENAHLADSSITSEKLAQHAVQSHHLEDDSVRSNHISSGAIQPGHLSDEAITGNKIADGSINLEKLAFNPFASSFQSGIESFMIPEGEKQTEVEITLPSPFSSSKYVAIAITDRPSCIISLINNNETSFTLLVRNIGDKAQKLTGSLFWLAINTTAEAWIPEKKIQPFSDEQPISEADPLLTISAYTEANEEEQSSDQPNFREERAKPVDDDEDTFDSSALSNRYYTDLSDEEAETVPTTFTKVSSSVNDEQEDSEETSLGNKETGEQAGNDSTRETSPETIPTTSAEVSSSVDDEQEDVEETSLGTEETGEQTENDSTTETSSETIYLHSQQEDPTSEEMKEIKEERDFDWWKQ
>NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase
MDYIVLTPSQLKKWRSSILLFAKKYGDRRITHKALRWLRNVKPGPFPEGTWMSVALEGRRLVGFICFGRYGMEEAFIVVHPSHRKKKVAETLLFHALEELDKVYTRVACDNVPSMKLCFSAGMIAFNLTTGPTGKPTLCFGGGEWSPEEFKKYMN
>NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein
MNYPKTGWLAVQGKGQSPVFFPHPRSTFHADPRSLSFILGPNMKKNVRIQSGAIQTHSPQMMPVRLIPTSQGDYLAGPFIAILTSSCRNGFRGNRQNFMDLIQTGRKMGVTIYVLTPEGIHPQSQTVRGWVLNTGNGKKRWLSATLPMPHVVYNRIPSRHMEQQAPEQKALKFFHQHPRINLFNPSFFNKWTLYQFLKESPQLKKLLPETHQWDAVTLKDMINKHGLLYLKPVDGKAGDGIIRVKSQDSSFEIIYQTLQRKQRITIKQWNDLLSKLTQLIGNRKYVVQQGIPLAKFQNRPFDLRLLMQKDKTGRWTLTGTGIRLAGREAISTHVPMGGSIGKMSTIMKSLFDDQSKKITWEIEQTGIQLATYIEEKYGRNLGEMSMDLGMETTGRLWFFEANSKPMKFDEPKIRSDSLQKLIHYMLYLSGFHPIHQKRR
>NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein
MSSIICKIQAISSPAPVQAVMLTQSLMKVWGCQHGQSIKISVGNKTLIARVLGIRRGGHTIYLHRTIISQLAIPYTKETRASFRQKELRLGPVLGILTTGYTGSPSAPFGLRSNLFRNFLLAAHEDKPFFYVFTPEMVDWTNRTVTGWFYLRNSKGSYHWIRHIAPLPEVVYERIPNRKAESLPQVKECRNRLTQITQAKIFNQGFFNKWSVHEMLYNQPLTSEHIPEAFPSPTVDIIRQMLDRHQMVYLKPIAGSLGLGIFRITRHPDGGYFCRFRGGNRNILRRFDSLESMLRHHFGPQMNRLPRYLIQQGIRLIKYNGRPVDFRVHMHKDSQGFWQVVGIGAKVAGIGSVTTHGRTGGSLLSVSEIFQTGENLEMEKRIKDAAIRIATTMEESVHGPLGELGMDIGVDRYRKVWLFEVNSKPGRHIFIHPSLRDAGRQSARYITKYSLKLAQFV
>NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein
MMGSASHTLGILTCKTLGAPPFKETAYFKQLTQTGREWGIQLIVFSPTDVDWNRKSVSAWSWDGKLSRWHRKNHPIPTLIYDRCYYLDSKHYLAYKPYVSKLVQHPGTQLLGRPLGGKIRTQKMLLNNPLLRPYLPPTIKYMGPETVRSALKTMGSILIKPNGGSHGRGVAAIFPDDNRRYRIKGRTRKNQEFHIQIQSEKLFLNWLTRFIGSTRYIIQPYLTLCTKDGRPFDLRILVQKGKKGQWETTGSAVRTGKTDSLTSNLHGGGKAERTASFLSTHIPETHRPAIIRSIQLLAREVPLQIEKEHGRLAELGLDIGIDQKYQVWLLEANSKPGRSVFLLTGEAHVRQRSIQLPIQYAYFLLNGNVGGSV
>NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein
MGHARVMIQIASERSFPPRANMMMSHSLIKRLSLSRSPIWVTYGSAANPAFIVPLHNHASIIRISIRLANQLKISSQRTVNVHFDTATRCLRFGPILGILMNEDIEGREAQQFGTMTRFLEECAQRCNTQGVCMTVVAPDRININTKSLKGWILDNKQWVLTESPLPDVLYNRITSRKLEKKVELREKIATLQHSYGIPIFNETFLNKQEVHDMLYQDIAMRRILPETYLYQPARLKSMLEKYRTVYLKPCNGSLGQGIIRITRHQRQFVCQYSEVTGTVTRVCSGLKELARQLARKMVNSRYIIQQGLYLVTWDSRPVDFRVLVQKDRRGKWSVTSSVARIANSQHIVSNLARGGTIRKAAEVLAGLQMDNKPALSHIRNTALTIAHTFEQLVQGHFAELGIDLVLDRQGRLWLIELNSKPSKTDDTITTPSLTIRPSVNRLIDYTLFITGWFQRFRQNRTSLQPKGSRRKTR

Crispr_ID: NZ_CP048104_4

• CRISPR_ID: NZ_CP048104_4
• CRISPR_location: 1069585-1070085
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of NZ_CP048104_4

Consensus_repeat	Method
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRISPRCasFinder
GTTTCAATACCTCATAGGTAAGATCAAAAC	CRT
GTTTCAATACCTCATAGGTAAGATCAAAAC	PILER-CR

spacers of NZ_CP048104_4

>4.1|1069615|37|NZ_CP048104|CRISPRCasFinder,CRT
AGGAACCATTATAGCCTGGGTGTCAGCCTTGATATTC
>4.2|1069682|38|NZ_CP048104|CRISPRCasFinder,CRT
GTTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGC
>4.3|1069750|37|NZ_CP048104|CRISPRCasFinder,CRT
GAATTCCCGATTCTTTTAAAATGATCTCCCATTCAGT
>4.4|1069817|39|NZ_CP048104|CRISPRCasFinder,CRT
GTACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTA
>4.5|1069886|36|NZ_CP048104|CRISPRCasFinder,CRT
TACGAACTATTTCGATGATGAGCTTGAAGAATATGA
>4.6|1069952|37|NZ_CP048104|CRISPRCasFinder,CRT
TTTCTACTCCTGATCTCTGACAAAGAGTTTATGAAAT
>4.7|1070019|37|NZ_CP048104|CRISPRCasFinder,CRT
TTTACCGGCAGGATCACCGGTAACATTACCGGCACGA
>4.8|1069616|37|NZ_CP048104|PILER-CR
AGGAACCATTATAGCCTGGGTGTCAGCCTTGATATTC
>4.9|1069683|38|NZ_CP048104|PILER-CR
GTTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGC
>4.10|1069751|37|NZ_CP048104|PILER-CR
GAATTCCCGATTCTTTTAAAATGATCTCCCATTCAGT
>4.11|1069818|39|NZ_CP048104|PILER-CR
GTACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTA
>4.12|1069887|36|NZ_CP048104|PILER-CR
TACGAACTATTTCGATGATGAGCTTGAAGAATATGA
>4.13|1069953|37|NZ_CP048104|PILER-CR
TTTCTACTCCTGATCTCTGACAAAGAGTTTATGAAAT
>4.14|1070020|37|NZ_CP048104|PILER-CR
TTTACCGGCAGGATCACCGGTAACATTACCGGCACGA

CRISPR arrays and Neighbor proteins around NZ_CP048104_4

CRISPR arrays

The CRISPR arrays of NZ_CP048104_4

>merge|NZ_CP048104|4|1069585-1070085|CRISPRCasFinder,CRT,PILER-CR
ATTTCAATACCTCATAGGTAAGATCAAAACAGGAACCATTATAGCCTGGGTGTCAGCCTTGATATTCGTTTCAATACCTCGTAGGTAAGATCAAAACGTTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGCGTTTCAATACCTCATATGTAAGATCAAAACGAATTCCCGATTCTTTTAAAATGATCTCCCATTCAGTGTTTCAATACCTCATAGGTAAGATCAAAACGTACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTAGTTTCAATACCTCATAGGTAAGATCAAAACTACGAACTATTTCGATGATGAGCTTGAAGAATATGAGTTTCAATACCTCATAGGTAAGATCAAAACTTTCTACTCCTGATCTCTGACAAAGAGTTTATGAAATGTTTCAATACCTCATAGGTAAGATCAAAACTTTACCGGCAGGATCACCGGTAACATTACCGGCACGAGTTTCAATACCTCATAGGTAAGATCAAAAC

>NZ_CP048104|4|4|1069585-1070085|CRISPRCasFinder
ATTTCAATACCTCATAGGTAAGATCAAAAC	AGGAACCATTATAGCCTGGGTGTCAGCCTTGATATTC
GTTTCAATACCTCGTAGGTAAGATCAAAAC	GTTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGC
GTTTCAATACCTCATATGTAAGATCAAAAC	GAATTCCCGATTCTTTTAAAATGATCTCCCATTCAGT
GTTTCAATACCTCATAGGTAAGATCAAAAC	GTACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TACGAACTATTTCGATGATGAGCTTGAAGAATATGA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TTTCTACTCCTGATCTCTGACAAAGAGTTTATGAAAT
GTTTCAATACCTCATAGGTAAGATCAAAAC	TTTACCGGCAGGATCACCGGTAACATTACCGGCACGA
GTTTCAATACCTCATAGGTAAGATCAAAAC

>NZ_CP048104|4|3|1069585-1070085|CRT
ATTTCAATACCTCATAGGTAAGATCAAAAC	AGGAACCATTATAGCCTGGGTGTCAGCCTTGATATTC
GTTTCAATACCTCGTAGGTAAGATCAAAAC	GTTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGC
GTTTCAATACCTCATATGTAAGATCAAAAC	GAATTCCCGATTCTTTTAAAATGATCTCCCATTCAGT
GTTTCAATACCTCATAGGTAAGATCAAAAC	GTACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TACGAACTATTTCGATGATGAGCTTGAAGAATATGA
GTTTCAATACCTCATAGGTAAGATCAAAAC	TTTCTACTCCTGATCTCTGACAAAGAGTTTATGAAAT
GTTTCAATACCTCATAGGTAAGATCAAAAC	TTTACCGGCAGGATCACCGGTAACATTACCGGCACGA
GTTTCAATACCTCATAGGTAAGATCAAAAC

>NZ_CP048104|4|4|1069586-1070085|PILER-CR
TTTCAATACCTCATAGGTAAGATCAAAACA	GGAACCATTATAGCCTGGGTGTCAGCCTTGATATTCG
TTTCAATACCTCGTAGGTAAGATCAAAACG	TTCAAGAAATTGGACTTTCCCATGTTGGTTGCACCGCG
TTTCAATACCTCATATGTAAGATCAAAACG	AATTCCCGATTCTTTTAAAATGATCTCCCATTCAGTG
TTTCAATACCTCATAGGTAAGATCAAAACG	TACAGAAAACCTACCGATTCAAGAGCAGGTCGATATTAG
TTTCAATACCTCATAGGTAAGATCAAAACT	ACGAACTATTTCGATGATGAGCTTGAAGAATATGAG
TTTCAATACCTCATAGGTAAGATCAAAACT	TTCTACTCCTGATCTCTGACAAAGAGTTTATGAAATG
TTTCAATACCTCATAGGTAAGATCAAAACT	TTACCGGCAGGATCACCGGTAACATTACCGGCACGAG
TTTCAATACCTCATAGGTAAGATCAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293841
NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein	unknown	unknown	gnl|CDD|377285
NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|224584
NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213235
NZ_CP048104.1|WP_173221124.1|1071365_1071785_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain	unknown	unknown	gnl|CDD|333735
NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein	unknown	unknown	gnl|CDD|214861
NZ_CP048104.1|WP_173221135.1|1082962_1083310_+|YlbF-family-regulator	unknown	unknown	gnl|CDD|237467
NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224196
NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein	unknown	unknown	gnl|CDD|377846
NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl|CDD|235465
NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047
NZ_CP048104.1|WP_173221108.1|1059447_1060269_+|ABC-transporter-permease	unknown	unknown	unknown
NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase	unknown	unknown	gnl|CDD|274273
NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein	unknown	unknown	gnl|CDD|377285
NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein	unknown	unknown	gnl|CDD|373047

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase	gnl|CDD|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	2.07705e-46
NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein	gnl|CDD|377285	pfam04293, SpoVR, SpoVR like protein. Bacillus subtilis stage V sporulation protein R is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR.	6.92725e-173
NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	1.00906e-97
NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	5.67586e-92
NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.16751e-07
NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.34184e-30
NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein	gnl|CDD|213235	cd03268, ABC_BcrA_bacitracin_resist, ATP-binding cassette domain of the bacitracin-resistance transporter. The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.	4.76648e-93
NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain	gnl|CDD|333735	NF012201, WIAG-tail, WIAG-tail domain. This 80-amino acid domain occurs in proteins in a single copy at the C-terminus. In most proteins, the domain immediately follows a long, variable run of tandem 10-amino acid repeats. The domain is named for its C-terminal motif, WIAxGx, hence the name WIAG-tail.	2.06249e-12
NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein	gnl|CDD|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.03968e-54
NZ_CP048104.1|WP_173221135.1|1082962_1083310_+|YlbF-family-regulator	gnl|CDD|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	3.54663e-22
NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	0.00144248
NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein	gnl|CDD|377846	pfam07485, DUF1529, Domain of Unknown Function (DUF1259). This family is the lppY/lpqO homolog family.	2.229e-47
NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl|CDD|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	8.61834e-170
NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	4.91639e-90
NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	9.67847e-13
NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase	gnl|CDD|274273	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.9474e-98
NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein	gnl|CDD|377285	pfam04293, SpoVR, SpoVR like protein. Bacillus subtilis stage V sporulation protein R is involved in spore cortex formation. Little is known about cortex biosynthesis, except that it depends on several sigma E controlled genes, including spoVR.	2.33134e-26
NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein	gnl|CDD|373047	pfam14398, ATPgrasp_YheCD, YheC/D like ATP-grasp. A member of the ATP-grasp fold predicted to be involved in the modification/biosynthesis of spore-wall and capsular proteins.	2.59708e-87

Protein sequences

>NZ_CP048104.1|WP_173221122.1|1068899_1069343_+|SMI1/KNR4-family-protein
MKDEVLKMIQIECDRVPEAFGGQVSEEEVEKAEGILGVKIQDDYKEFIRRFGAGCVGQAVILGLREAEFFPTPSFIEESLDFRKHLPSAYSKMVVIGVDGAGNPIGFIYPSEMIFVYDHDFGGRYDLANSFEDYILKALNRTLGIHF
>NZ_CP048104.1|WP_173221120.1|1066008_1067406_-|recombinase-family-protein
MTVALYCRVSTDEQVQQGFSIDNQKERLQAFALSQGWTDYRFYIDDGYTGTNMDRPGLKRMIQHAEDGTIRTIVVYRLDRLGRRQKDVLFLLEDVFEKSNVAFKSATEPFDTATPLGKAMIGILAVFAQLERDTIVERTTAGRRQRIRSGKWYGGRVPFGYQWNSTTQTLEVVPEESTLVKEAFSMYLQGHSSSYIADWLTSRSTARFFDHSVIRTMLQRPIYTGHMNNAGKLVEGQHEGIIDGETYERVQQELHKRQTGRPPVGEYLLSGILRCGICGGPVIHVWASGKRYEYYACKAQHVRQRNKGHHCSLGYTRKEKLDSWVAERLKQISLNPEQVEVQLKTLTTMQQEQRDRTAELEQRLENINHRLERWYDAFEQGLLNPAQLKKRIDSLEEERKTVMIRLDELDHTPKEQWAEGVIQTLETIGEAWDSMNFSEQKMVLRAALDHIVLFPDREPKLIWNV
>NZ_CP048104.1|WP_173221118.1|1065807_1066077_+|SpoVR-family-protein
MADHLQELERSVHEITEIARGFGLDFFPMRYEICPADILYTFGAYGMPTRFSHWSFGKGNHRKYEKPLNVPYQLWLSIREQDNMIQCGS
>NZ_CP048104.1|WP_173225234.1|1064706_1065735_+|MBL-fold-metallo-hydrolase
MWTLIIGIPFAVIILSISLMGWRYVKFRGKVPRPRARGIRRRFHPEELSDDDISLAWIGHSTVYINLYGIKILTDPVFSHRVGVSLFPGITVGLKRYTPPAVSLEEVKGVDLILLSHAHLDHLDMPSLKALADSGTQVITAKNISHLLKKLSFGRIDELSEGETIDWGKGLKVTSIPVKHWGSRFPWNKEYGWTGYELEIRGKRVVFAGDTAYTPSFRKLGEAGAVDVMIMPIGAYSPDEFQKSHCTPEQAWEMTVDSGAKKMVPIHWNTFVLSREPIEEPMERLLKAAGEQADRIVIREQGEIWRLSANTEISLSEPIGERKSVSLYQKKEVSSRVNPSAT
>NZ_CP048104.1|WP_173221116.1|1064105_1064501_-|DUF1259-domain-containing-protein
MSSLQRLCEQFARIVGGEASVLNGVCFIQKFRRFPITILGRRTRSPLVNPTFFSFESIDKKGRALNLGETVILQNEINPFISVLRKEGIKVTALHNHWLFENPRLFYIHFESVENPIIFARKVARALKVLK
>NZ_CP048104.1|WP_173221114.1|1062372_1063881_-|phytoene-desaturase
MEKKVIVIGGGLGGLSAAVCLAVEGYSVTVYEQGSQVGGKLNKQTGKGYSFDTGPSDLTMPWVLEQLFTRAGKKMDDYFSLIRIKPQWKAFFSDETTLELTSDLPFLFQQMKEQFDTEATALLQYLQHCSKMYELTQKSYYKKSLAGSEEMRKMHSMKEWMSLSSMKSVHQKTSQYIQSPHLKQLFDYLSISIGSSPHQAPVFLSLMTHSLLGMGSFYAQGGMYTIAEGIERLLQELQVKVHTNMKVSAIQYDNQERVKGILLQDGTIVPADIVICNRDPVTAYHSLLSNHSKVESAIRDLNKYPPGLSGMVLLLGVKGTYDHLQHRNIFFSANPQEEYEQLFKEGKPATDPTISVHLSCKSDPGQAPKKKSNMVVLTHVPPLKPGESWEPYRRQYRDRIIEKLEQRGITNLEKNIEIETQFIPDDFHHLYGANGGSLYGVAADRKKNNGFKIPCRSTLLQNLYFVGGSIHPGGSIPMASLSGQLAADLIIKDHAIIPVPTA
>NZ_CP048104.1|WP_173221112.1|1061111_1062182_-|type-2-isopentenyl-diphosphate-Delta-isomerase
MTSNNYPTDKRKSEHIDIVLNQKVTGTNITTGFEAYQFRHNALPEINFDDVSLYTTFLGKPLKAPFLVSSMTGGTDQAWKINKHLAVAAEEQGWAMGLGSVRAAIEQPSTAYTFQLREYAPTIPILANLGAAQLNYGYGVNECRQVVELTQADALIFHLNSLQEVFQPEGDTRFRSLIRQIAEVCKKLDVPVGVKEVGWGIDGKVAKLLFEAGIHFIDVAGAGGTSWSQVEKYRSQHKDPLRYQAAEAFTDWGIPTAECVIDVRQRNPQGTVISSGGLYTGVEGAKAIALGADLAGYGRSLLTAATQSTPEQLRFVMQRIELECKIAMFGIGAATLSDLKRTDRIHHIHTRTTFRT
>NZ_CP048104.1|WP_173221110.1|1060317_1061091_+|ABC-transporter-permease
MKELIISEWERAWGRKKTQMLLIVYPVLVFLMEVFMLQFGVGFYDMEHEVALHALNFPLFSLRDLSLLLVFVIAPMLWVDSFSGEYSTGAYRMVLIRPYSKGKLLAAKWVSQAALTGILLLIPFVMSQIVGWINLPNPSVTTFFYEGAERYDMGEALLYQLCFYGWIFLILLVCQSVCALLGTWMPNPILSFLAYAGGLIGSIYLSDSFIILFGHTDEVFRLMAGKAEVSVYYVLFGTLVVSLVSIYGSWKKKDWVK
>NZ_CP048104.1|WP_173221108.1|1059447_1060269_+|ABC-transporter-permease
MLALIRSEWERLWCRKLTWLLFGLIPVMTIAGARYMKGEHAHLSPDKPQYAVFHNFPVLALAEMLITAVNLILILWLIVSMTQEYRTGQLRMVMLRSYSPVAIFSAKWLTVIAALFLYLAVFFMVSYITGWFLLPKTESLTLFYHPGTATGWEAFWYNLQYYGMAFITLIVMSSIIMCIAVASPTSTTAIGISLGFVLVSFGYIHILQMFTMNYPVHPKWYYLSLVQIQYEGITLLLAVKPMLGKWISMVLATYGGVFMGTSWLLVRRQDRFM
>NZ_CP048104.1|WP_173221106.1|1058539_1059448_+|ABC-transporter-ATP-binding-protein
MDTDVLLEVKNVTKKVRGRTLLHDVSFGVRKGEICGFLGPNGAGKTTMIRVMTGLIAPSQGEVRINGISVQQNRQRALSSLGAIVESPLFFPYLSGRKALGNLSRLHPNLSRKEQKKQVEKVLELVGLKDRGNDKVGTYSLGMKQRLGIAQALLGKPEVIILDEPANGLDPIGMRFLRELILKLRDEEGLTFLISSHLLDELQQVCDRLVMIKEGSLVWEGDSDELAGGVTWVFTVGNVDLALQAIGNAYPVKCLDDRQLEIVIEEDQVGHVSRLMMAQGIDVMGIEKRTRRLEDAFVEMMS
>NZ_CP048104.1|WP_173221123.1|1070696_1071275_+|GNAT-family-N-acetyltransferase
MSNEKHVVKLLEGRRVYLRPPETEDVPLLYRSFYHPEVRRLTGTTQMLSVEGMENWLEKVVKDESRLFLLIVDQEKDEVMGDIELLDMHQVHRSAWIRIALHREEYFGKGYGTEAMHLMLNHGFHSLNLHRIELEVYDYNHRAIRTYERLGFRREGVRREGLFHNHAYHDVILMGLLAHEYEFPGEVKDYQK
>NZ_CP048104.1|WP_173221124.1|1071365_1071785_-|hypothetical-protein
MKTKLFALGFAFLLAISLFSTSSNVATASEVSTNEYLNETVTFKETVDTPVFTHDEKKGNLQLDTYATYLEDKADFDYFVVTLYEAGSDVTMGNKVALYTNDLDIAAWDVPSGKYYFRFEKPRNGLKLKVKYSVYPYNG
>NZ_CP048104.1|WP_173221125.1|1071857_1073111_+|SpoVR-family-protein
MTFSYLRCIAKAFHRMKTDYDLDLGRIYELVINSNPCYAFLLEGNSLIQNKLIIAHVLAHSDFFKNNVRFSNTSRDMVESMAASAERIRRYEMDYGKDQVEAFLDHVLAIQEHIDPGLIRRPRKKEKSSSSDNRHSTPYDDLWALERREEDKNEQKSGTSKVQEKDILLFAMENNPKLQDWQQDILTVMRDEMLYFWPQLETKIMNEGWASYWHIRILREMNLTNEEVLEFAKLNALVTQPSSGSINPYHLGLKIFEDIERRWDHPTEDEQVRFGRKPGQGRQKIFDVREMEMDTSFIRNYLTRELTEEMDLYIFQRKGAEWTVTDKEWQKVREQLIASRVNGGYPYIVVEDGDYQDKGELYLRHRFEEMELDIKYVEKTLPHVHALWGRPVHIETVVENRPVLFTYNGKRCSRRFL
>NZ_CP048104.1|WP_173221126.1|1073163_1076958_-|WIAG-tail-domain
MSKVSRKKRPSLRQRTQPTTRMEDEWVLEKIIQKELEDIKKQATLSSEQRSSSENKSTSSPPPAQALTMNRDATNGSKNLQPATTHSSDRVQQVEKIKRNRTQGNGNAFIYTGDLVDESITNEKLANDSIDSSKIQASAVEKEHLRDQSVNSSKLADGSVHATKIAPRAIKEYHLSADSISGDQIQREAIQTEHIKEGGILGNRLSDYSIDGTKIKDHSIQANHLTPKQIQGSHLADQTITASKIESGSIHTNLLANEAVNQAKMAEGAVAAKNLQAGSVTMDKLAEESVSSEKIVPQAIQKNHLDHGIIDSHHLSDHAVTNQKIAPEAVDGTSIKKESITGEHIEQGTIENYHLTHSSVNQEHIAPGSIEAKALQNESIQSKHISHHSVQTHHLGDSVVTGNKIAPNSIQSEHLEMKNIHSFHLADQSVQEQHMAPQSIGSTHFQRDSVLTEHIKEGSILGNRLADYSIDGTKLKNYAIEGHHIAPKQIQGSHLEDQTITASNIETATITSNLLANEAVNRTKLADESVSTDKLQQNAVTSEKMAEGAVTSDQLALQSIQSKHLDHHIIDNHHMMDLVVTSSKLAPESVGSDTIQTEAIQSHHLGQQTIQGEHLADDSIHQDKVAPDAIGSDAVQKQAIHSQHLADNTVQTYHLTDNSVTGEKLADRSVTTSKLCPESVSTDKLIDYSITNSKLGNQVVTSNKLSPESVRGDHIQTDAISAIHIQDEQIHASHLVDRTITSEKLAPQSISEEHIAQESLSSKHIAQDTIGPDHLTMESIQSRHLALDSIQSQHIEEEAITGEHLCPYSITADKLADGTIQSRHLDDEILMARHIGERQVESSHLADSLITSEKLATRSIQGNHIEKEAISDEHLCPYSINADKLADGSIQSRHLNDEILTARHIGESQVENAHLADSSITSEKLAQHAVQSHHLEDDSVRSNHISSGAIQPGHLSDEAITGNKIADGSINLEKLAFNPFASSFQSGIESFMIPEGEKQTEVEITLPSPFSSSKYVAIAITDRPSCIISLINNNETSFTLLVRNIGDKAQKLTGSLFWLAINTTAEAWIPEKKIQPFSDEQPISEADPLLTISAYTEANEEEQSSDQPNFREERAKPVDDDEDTFDSSALSNRYYTDLSDEEAETVPTTFTKVSSSVNDEQEDSEETSLGNKETGEQAGNDSTRETSPETIPTTSAEVSSSVDDEQEDVEETSLGTEETGEQTENDSTTETSSETIYLHSQQEDPTSEEMKEIKEERDFDWWKQ
>NZ_CP048104.1|WP_173221127.1|1077114_1077582_-|GNAT-family-N-acetyltransferase
MDYIVLTPSQLKKWRSSILLFAKKYGDRRITHKALRWLRNVKPGPFPEGTWMSVALEGRRLVGFICFGRYGMEEAFIVVHPSHRKKKVAETLLFHALEELDKVYTRVACDNVPSMKLCFSAGMIAFNLTTGPTGKPTLCFGGGEWSPEEFKKYMN
>NZ_CP048104.1|WP_173221128.1|1077586_1078906_-|YheC/YheD-family-protein
MNYPKTGWLAVQGKGQSPVFFPHPRSTFHADPRSLSFILGPNMKKNVRIQSGAIQTHSPQMMPVRLIPTSQGDYLAGPFIAILTSSCRNGFRGNRQNFMDLIQTGRKMGVTIYVLTPEGIHPQSQTVRGWVLNTGNGKKRWLSATLPMPHVVYNRIPSRHMEQQAPEQKALKFFHQHPRINLFNPSFFNKWTLYQFLKESPQLKKLLPETHQWDAVTLKDMINKHGLLYLKPVDGKAGDGIIRVKSQDSSFEIIYQTLQRKQRITIKQWNDLLSKLTQLIGNRKYVVQQGIPLAKFQNRPFDLRLLMQKDKTGRWTLTGTGIRLAGREAISTHVPMGGSIGKMSTIMKSLFDDQSKKITWEIEQTGIQLATYIEEKYGRNLGEMSMDLGMETTGRLWFFEANSKPMKFDEPKIRSDSLQKLIHYMLYLSGFHPIHQKRR
>NZ_CP048104.1|WP_173221129.1|1078921_1080295_-|YheC/YheD-family-protein
MSSIICKIQAISSPAPVQAVMLTQSLMKVWGCQHGQSIKISVGNKTLIARVLGIRRGGHTIYLHRTIISQLAIPYTKETRASFRQKELRLGPVLGILTTGYTGSPSAPFGLRSNLFRNFLLAAHEDKPFFYVFTPEMVDWTNRTVTGWFYLRNSKGSYHWIRHIAPLPEVVYERIPNRKAESLPQVKECRNRLTQITQAKIFNQGFFNKWSVHEMLYNQPLTSEHIPEAFPSPTVDIIRQMLDRHQMVYLKPIAGSLGLGIFRITRHPDGGYFCRFRGGNRNILRRFDSLESMLRHHFGPQMNRLPRYLIQQGIRLIKYNGRPVDFRVHMHKDSQGFWQVVGIGAKVAGIGSVTTHGRTGGSLLSVSEIFQTGENLEMEKRIKDAAIRIATTMEESVHGPLGELGMDIGVDRYRKVWLFEVNSKPGRHIFIHPSLRDAGRQSARYITKYSLKLAQFV
>NZ_CP048104.1|WP_173221131.1|1080291_1081413_-|YheC/YheD-family-protein
MMGSASHTLGILTCKTLGAPPFKETAYFKQLTQTGREWGIQLIVFSPTDVDWNRKSVSAWSWDGKLSRWHRKNHPIPTLIYDRCYYLDSKHYLAYKPYVSKLVQHPGTQLLGRPLGGKIRTQKMLLNNPLLRPYLPPTIKYMGPETVRSALKTMGSILIKPNGGSHGRGVAAIFPDDNRRYRIKGRTRKNQEFHIQIQSEKLFLNWLTRFIGSTRYIIQPYLTLCTKDGRPFDLRILVQKGKKGQWETTGSAVRTGKTDSLTSNLHGGGKAERTASFLSTHIPETHRPAIIRSIQLLAREVPLQIEKEHGRLAELGLDIGIDQKYQVWLLEANSKPGRSVFLLTGEAHVRQRSIQLPIQYAYFLLNGNVGGSV
>NZ_CP048104.1|WP_173221133.1|1081409_1082834_-|YheC/YheD-family-protein
MGHARVMIQIASERSFPPRANMMMSHSLIKRLSLSRSPIWVTYGSAANPAFIVPLHNHASIIRISIRLANQLKISSQRTVNVHFDTATRCLRFGPILGILMNEDIEGREAQQFGTMTRFLEECAQRCNTQGVCMTVVAPDRININTKSLKGWILDNKQWVLTESPLPDVLYNRITSRKLEKKVELREKIATLQHSYGIPIFNETFLNKQEVHDMLYQDIAMRRILPETYLYQPARLKSMLEKYRTVYLKPCNGSLGQGIIRITRHQRQFVCQYSEVTGTVTRVCSGLKELARQLARKMVNSRYIIQQGLYLVTWDSRPVDFRVLVQKDRRGKWSVTSSVARIANSQHIVSNLARGGTIRKAAEVLAGLQMDNKPALSHIRNTALTIAHTFEQLVQGHFAELGIDLVLDRQGRLWLIELNSKPSKTDDTITTPSLTIRPSVNRLIDYTLFITGWFQRFRQNRTSLQPKGSRRKTR
>NZ_CP048104.1|WP_173221135.1|1082962_1083310_+|YlbF-family-regulator
MNPYDKAHELAGAIRRSEEFRQLLESWDGIKDVEDRGVLDRYRELQMEYQVQVSQGKEVSGDSMRELEVLMKKIKERKDLSRVLEAEARIGTLMGDINRIVTEPLEKFYHSHWKK

Crispr_ID: NZ_CP048104_5

• CRISPR_ID: NZ_CP048104_5
• CRISPR_location: 1698788-1699015
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_CP048104_5

Consensus_repeat	Method
GTTTCAATACCTCATAGGTAAGATCAAAAC	PILER-CR
GTTTTGATCTTACCTATGAGGTATTGAAAC	CRISPRCasFinder
GTTTTGATCTTACCTATGAGGTATTGAAAC	CRT

spacers of NZ_CP048104_5

>5.1|1698818|35|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
AATCCTGGAGATGCCCATTTGATCAGGAAAATTGA
>5.2|1698883|37|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT
GTTGGTCTGCGGTGAAATGTTCCATCATCTCAGCTAT
>5.3|1698950|36|NZ_CP048104|CRISPRCasFinder,CRT
GATCCGTCAAATGACCGTTGAGTGCATCGACGATTA

CRISPR arrays and Neighbor proteins around NZ_CP048104_5

CRISPR arrays

The CRISPR arrays of NZ_CP048104_5

>merge|NZ_CP048104|5|1698788-1699015|PILER-CR,CRISPRCasFinder,CRT
GTTTTGATCTTACCTATGAGGTATTGAAACAATCCTGGAGATGCCCATTTGATCAGGAAAATTGAGTTTTGATCTTACCTATGAGGTATTGAAACGTTGGTCTGCGGTGAAATGTTCCATCATCTCAGCTATGTTTTGATCTTACCTACGAGGTATTGAAACGATCCGTCAAATGACCGTTGAGTGCATCGACGATTAGTTTTGATCTTACCTATGAGGAAACACAAA

>NZ_CP048104|5|5|1698788-1698949|PILER-CR
GTTTTGATCTTACCTATGAGGTATTGAAAC	AATCCTGGAGATGCCCATTTGATCAGGAAAATTGA
GTTTTGATCTTACCTATGAGGTATTGAAAC	GTTGGTCTGCGGTGAAATGTTCCATCATCTCAGCTAT
GTTTTGATCTTACCTACGAGGTATTGAAAC

>NZ_CP048104|5|5|1698788-1699015|CRISPRCasFinder
GTTTTGATCTTACCTATGAGGTATTGAAAC	AATCCTGGAGATGCCCATTTGATCAGGAAAATTGA
GTTTTGATCTTACCTATGAGGTATTGAAAC	GTTGGTCTGCGGTGAAATGTTCCATCATCTCAGCTAT
GTTTTGATCTTACCTACGAGGTATTGAAAC	GATCCGTCAAATGACCGTTGAGTGCATCGACGATTA
GTTTTGATCTTACCTATGAGGAAACACAAA

>NZ_CP048104|5|4|1698788-1699015|CRT
GTTTTGATCTTACCTATGAGGTATTGAAAC	AATCCTGGAGATGCCCATTTGATCAGGAAAATTGA
GTTTTGATCTTACCTATGAGGTATTGAAAC	GTTGGTCTGCGGTGAAATGTTCCATCATCTCAGCTAT
GTTTTGATCTTACCTACGAGGTATTGAAAC	GATCCGTCAAATGACCGTTGAGTGCATCGACGATTA
GTTTTGATCTTACCTATGAGGAAACACAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213192
NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein	unknown	unknown	gnl|CDD|372502
NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|236841
NZ_CP048104.1|WP_173222184.1|1709233_1709449_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|276809
NZ_CP048104.1|WP_173222180.1|1708112_1708712_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease	unknown	unknown	gnl|CDD|372235
NZ_CP048104.1|WP_173222182.1|1708823_1709228_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|319258
NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NZ_CP048104.1|WP_173222155.1|1688411_1689089_+|TerC-family-protein	unknown	unknown	gnl|CDD|163429
NZ_CP048104.1|WP_173225401.1|1703831_1704299_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222153.1|1687276_1688017_-|NTP-transferase-domain-containing-protein	unknown	unknown	gnl|CDD|133019
NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein	unknown	unknown	gnl|CDD|212133
NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase	unknown	unknown	gnl|CDD|236199
NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|214864
NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein	unknown	unknown	gnl|CDD|223841

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.61271e-57
NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein	gnl|CDD|372502	pfam13157, DUF3992, Protein of unknown function (DUF3992). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 98 and 122 amino acids in length. There is a single completely conserved residue T that may be functionally important.	0.00148105
NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	1.91068e-15
NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase	gnl|CDD|236841	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional.	1.4888e-43
NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.98958e-15
NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.52613e-12
NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease	gnl|CDD|372235	pfam12639, Colicin-DNase, DNase/tRNase domain of colicin-like bacteriocin. Colicin-like bacteriocins are complex structures with an N-terminal beta-barrel translocation domain (pfam09000), a long double-alpha-helical receptor-binding domain (pfam11570) and this C-terminal RNAse/DNase domain with endonuclease activity. Their competitor bacteriocidal action is by a process that involves binding to a surface receptor, entering the cell, and, finally, killing it. The lethal action of colicin E3 is a specific cleavage in the ribosomal decoding A site. The crystal structure of colicin E3 reveals a Y-shaped molecule with the receptor binding domain forming a 100 Angstrom long stalk and the two globular heads of the translocation domain and this catalytic domain comprising the two arms.	2.24887e-11
NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein	gnl|CDD|319258	cd16401, ParB_N_like_MT, ParB N-terminal-like domain, some attached to C-terminal S-adenosylmethionine-dependent methyltransferase domain. This family represents domains related to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, fused to a variety of C-terminal domains, including S-adenosylmethionine-dependent methyltransferase-like domains. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	3.30541e-28
NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67125e-61
NZ_CP048104.1|WP_173222155.1|1688411_1689089_+|TerC-family-protein	gnl|CDD|163429	TIGR03717, R_switched_YjbE, integral membrane protein, YjbE family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family commonly are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains protein YjbE from Bacillus subtilis. A transport function is proposed.	2.95555e-71
NZ_CP048104.1|WP_173222153.1|1687276_1688017_-|NTP-transferase-domain-containing-protein	gnl|CDD|133019	cd02538, G1P_TT_short, G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase. This family is the short form of glucose-1-phosphate thymidylyltransferase. Glucose-1-phosphate thymidylyltransferase catalyses the formation of dTDP-glucose, from dTTP and glucose 1-phosphate. It is the first enzyme in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme.There are two forms of Glucose-1-phosphate thymidylyltransferase in bacteria and archeae; short form and long form. The homotetrameric, feedback inhibited short form is found in numerous bacterial species that produce dTDP-L-rhamnose. The long form, which has an extra 50 amino acids c-terminal, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced.	5.20198e-129
NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein	gnl|CDD|212133	cd11523, NTP-PPase, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily. This superfamily contains enzymes that hydrolyze the alpha-beta phosphodiester bond of all canonical NTPs into monophosphate derivatives and pyrophosphate (PPi). Divalent ions, such as Mg2+ ion(s), are essential to activate a proposed water nucleophile and stabilize the charged intermediates to facilitate catalysis. These enzymes share a conserved divalent ion-binding motif EXX[E/D] in their active sites. They also share a highly conserved four-helix bundle, where one face forms the active site, while the other participates in oligomer assembly. The four-helix bundle consists of two central antiparallel alpha-helices that can be contained within a single protomer or form upon dimerization. The superfamily members include dimeric dUTP pyrophosphatases (dUTPases; EC 3.6.1.23), the nonspecific NTP-PPase MazG proteins, HisE-encoded phosphoribosyl ATP pyrophosphohydolase (PRA-PH), fungal histidine biosynthesis trifunctional proteins, and several uncharacterized protein families.	1.62942e-15
NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase	gnl|CDD|236199	PRK08244, PRK08244, monooxygenase.	0
NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	1.12714e-65
NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein	gnl|CDD|214864	smart00860, SMI1_KNR4, SMI1 / KNR4 family. Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.	1.88517e-05
NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein	gnl|CDD|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	4.73994e-14

Protein sequences

>NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator
MTHVDVNEIGEIIRKVRKEKGLRLEDLADENISPATISNLERGVPHVKHDKLTYLMEKLNIKINQIPDLIMKEHQKLQHLQFNLFAIESLRDNGYPEEALCKIDELDIDDSNPYIAHIHLLKGKCYNSLGKWKKAERAFFNAIRHMNNNHSDKQSNIEAASFTGLSLCSFFQNNLDQALVYTESGLEAFVEDGERSQYKYVLFQNKAMFLEKQGRPIEALKVVQDSWNFLPKIEQIEVILGFYWLRAELLRHTGLYQDAIHYAKEGLEKARFNHEYCRQFDLWTVLGSTYMALKEWDQAESCFELALKLKDRFPNGEILTSAYARLGILYMYQKKWNEAKDAILKAIQKGEEFNDAPRLAYAFIVMGHYYQKRKEFNEAITYYQRSLDLARNHNYRQKERLALHLLAECLEEIDEQEFQSCVRNMYIAQKNIYHEEGIALEKME
>NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein
MGGTLIRGKANYRVQSANLGKPKYLRQNQIYFYSKSRSWDDQLAALRRIRPVAAVIPHHLASHLPKEIAVITHSQVPSAYWRLALWNFKKLPVHVVAITGSAGKSTTTEMVDSILKQSKQVVKTQGNLNTFMF
>NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase
MSSLFVKTKRQQELYREVSQLADRFSESSAHIDKHGIFPTDQINALRNSGYSGLVVPKKYGGEGITVYDMVLLQERLAKGDAAIALCIGWHLGVLADIAEKKRWNEEVFEFIAGETLKGALVNRAATEAQTGSPTRGGRPQTHAVKQNGKWIINGRKTFTTMAPVLDYFLVTAWIEEKQAVGEFLLHKDLKGIKIEETWDMIAMRGTGSHDLILTDVEVDRSMLVEVISKPRSAQVNGWLLHIPACYLGIAGSARDYAVEFANQYSPNSLNGPIKELPHIQSLVGKMELELLQARHFLFSVAEAYCISENRHLLGSELAAVKYTVTNTAISVVDKAMRIVGAKSLHRTNPLQRYYRDVRAGLHNPPMDDATLVKLAHNAFNLTN
>NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein
MLKSLIGLVKKTEGIIEINNKQIGSTTTFDLFADIGYVFQNPDTQLFCHTVEEKIQFGLKNRQIQPDELQERTERILEIIGLSHVRLAHPFSLSRGQRQKLAVATMLITNPSIILLDEPTTGQDEGSLLSLLTLLRKLVEENKTTIVMITHDMEVVAKYAT
>NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein
MNTTTFQKWVEEFYDGRGWSHYDPFIRVGFLMEEVGEVARVVRAIEIGRDRPDEKRMSEDVLKEELTEELGDVLANLIILAEKYDIDLEEIMNHHVQKLTKRFTEEQV
>NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein
MYECKVRNRNTRNRRLKKRKIKCKGPQHRKCMHKFRKKPAKKQKGTPVSHKLCGNILLNDQHTLEIMEIWKKRIKQDATLTLSVFNSTGSTAPLQVLVNRKEEKSDTFTVPPGNTLSTTVCNVDSIRVFRIDKGKVEGKFCLDIVFPFSAKKQIRSHSIRFSQEELAGV
>NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase
MTKKIFIDPGHGGSDSGATGNGLKEKDLNLAIALEAKKVIQDEYTDHSIKMSREKDETVSLTQRTDAANRWGADFFLSIHINAGGGTGFESYRYVEKGSDTTMTVQKHVHAFILSASGWKDRGKKWANLHVLRESKMPAVLTENGFIDTDTDAKKLKDPSFVKKLGRAHAEGLAKALGLKRKESDPEPEPGNLYIVQAGAFKDRKNAEVRVKALKEAGFEAFIQIK
>NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase
MGKITFRRLDESDVFLYREFILTGCRETPLDVGLTEKEWGAKNTYKALEEQFRQHDNNPGCFILGAYDGNKMVGTLGFTRNEPIMRRHIAWIWGVQVDSQYRNQGIAKSLFKEMLIRSRECKGLEQIRLKVRSDNEKAIKVYQSIGFQFIAKEPGVLKWGDRYIDQFWMMMSL
>NZ_CP048104.1|WP_173222155.1|1688411_1689089_+|TerC-family-protein
MEVLSIEFFQALVAIIIIDLVLAGDNAIVIGLAARNLPRDKQKPVIVWGTIGAILIRATATLVVVWLLEIPGLLLAGGILLIFIAFKLLIEEKAQEDVKASKSMIGAIQTIIIADAVMGLDNVLAVAGAAHSNYLLVILGLLISVPIMVWGSTLILRLIERYPAIIYIGAGVLAWTSGKMIVDEPFLKSFFEEEPIIKWGLILFIIAGVLFFGRLTNKKKQTVQN
>NZ_CP048104.1|WP_173222153.1|1687276_1688017_-|NTP-transferase-domain-containing-protein
MKGVILAGGTGSRLYPLTKVTNKHLLPVGRYPMIYHPISKLVECGIREILVVTGLEHMGDVVRLLGSGADFQARFSYKVQDRPGGIAQALQLAADFAKGDPLLVILGDNVFSDSLKPFMKSFLQQGSGAKLLLKKVDQPERFGVAEIEGNKITGIEEKPKYPKSSYCVTGIYMYDPSVFSYITQLSPSARGELEITDVNNLYIQNSILTFDLLQGWWSDAGTPSSLLRANQLASDIILTFPQESGG
>NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase
MNKRIKGAEYLSNFESIFKCPICDSPMNVFELKSLICSNNHTFDFTKQGYINLTTYPVKTRYSKDLFEARRKLIAEDGFFEPLSQAIAEIINKHTAVKKGTISLIDMGCGEGSGVLVATKSYTHKIWAVADLSKTPFKDKQFDVILNILSPSNYKEFNRLLKADGFVVKVVPQSGYLKELREVIFDKPEKQSYSNVDTVERFNENFQLVDRSRLCYTVTLDNPSIQSLVQMTPLSWATTDKQVKSFLEGDSVQITFDLEILIGKK
>NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase
MDFEVIVVGGGPVGMMLASELALAKVKVCVLENLKETTPYSRALTVHPRTLEIFDSRGLKEKIMSKGMPISKGHFAVLDTPLDFSTLDSTSNYTVFIPQHDTEIELEKWARSLGVEIRRGEKVVSVRQDHQGVEVVSVSSNGDSVLSAAYVVGADGGGSIVRKQANIPFVGKNSTFTALMGDVVLSNPPESNVISRFSERGLVMVAPVNAQLHRVVMVDPERMDVPKEEPVTLEELRSGLVRILGSDLGITEPFWMSRFGNATLQVERYREGRVLLAGDAAHIHFPAGGQGLNVGLQEAMNLGWKLAAEIHGWAPDWLLDSYHEERFPVSTAMLKNTEVQTLLFEFSPRMIELRNMLSSMLKIPESNYLLSTQISGFNVKYETDAKALPHALNGCRFTELKLRLENGTIRNAYELFHSGTFLLLHLASDECMTYAVDWSRYKHVQVVRATLAEEAPDWKDVHTALIRPDGYIAWAVSKSELGRMETIKKGISRWCGGHGIS
>NZ_CP048104.1|WP_173225401.1|1703831_1704299_-|hypothetical-protein
MSLGYDQDSFEFWLMDMDDAIERLFSLLPSEVTGHLDYSEYSLNHIEKWILDQYMDTNSIIEKSEKMTLDGLARYVGETFRMAFKGKWIISLDDPDKAFHMIPQVIFSDYEVNSISPVTLVTASADRRLGNYLSTVYRNVKQSKKALYKGYFVRV
>NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein
MNKINWKYDEGLVGEKAVKKTEELLNTRLPEDFKKIATENDCGVPHPGRYSFNDGVMVFGQLFSIDPKRDNNIVEVTRIGRSEHGMSDNIVAFADDPAGNFLCFDYSQLNNGYPAIIFWDHEIEGGDPETICSTFTELLNMFHEDVDEKK
>NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein
MEWLKLDEPLSEREITQVEDQLGLKLPEDYVKWIRQYEGPESDFVSVDVNGEPHDVEGFYGPESLVDEMNLIFESREEYKGHGIIIPFAIDSILSKYCFFYPKGSQEPSGVFFRSRDVDLSDIFEGNDIKKSLYISQTFQGFLDKLYIDEDWI
>NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease
MVASIEQHIACINEESTCQKGGANENKTGSNVKPHDSNPPDNKNGESSFWDTLGNTVSDGWNQTKKVAGDAWGRIKQEVKEETESLKGTSFKERMKKSIQWSLEWIPGISGISTDIKKLTGFNLIEWISENPGSTLLNAAGIALIFVPGGQGAGAATFINIARTLGWGIVGGSGVGGIVAGLTGGDISDGILYGGLAGLVGGGVGGGVYRGAASFFSRYGGSLVQKWLPGSLGGGSGAFADMATFEWLTQGKVDWKKAGLTGAMIGALTFGGGMFLDKAGPAIGQAMKQFGFNVNIGADGTIAMPWVREAEENVRKSSGSGGTQTPFKARKPPKLSQGDPNFSFKSEWDEKTKELWVTTSDGRKFKVNYGEKRNTVETKTTKEGNTYTVSYDGDAFPDFSPYAVKSKNGEPIEIILPDDTLVGPSSDQTRYTTQLLKEKYPNWRTEFGFTESQIASIEKNKGSIGPGIFKNSAEQLTWHHDKETGKLILVPYDLNNTFQHSGGHQFWGSQK
>NZ_CP048104.1|WP_173222180.1|1708112_1708712_+|hypothetical-protein
MAIETGLTEVFLSGAVGALVGAWIGGKTAGREQRRTEVYKMKRKALEDLDGKVMHFYFQFLDGLEYDCFNPSKKRELPNKKTILHLKQLRNVAKQQHNLCYYRGYLDHAETFMIDVFDVADRIFQVIENEQIPSYKELSRAEDVFDEATKAIESVIRELEGEFNPTITSLWKRQKYKISMWKIRRNIKRKEKKQQEQIT
>NZ_CP048104.1|WP_173222182.1|1708823_1709228_-|hypothetical-protein
MIRELRAEVNRLNELVPETEERPLKEEKDSLQVVDGEQEEQDFSGDPIFKGDGNKTNLGVNITKPPRTCWGLWRFRLFFPDGNDIPRLKLIRFTYSLDHIGGERENDLPKLLRKFEETIRFPFGNPFFGELDGF
>NZ_CP048104.1|WP_173222184.1|1709233_1709449_-|hypothetical-protein
MNKINWKYDEGLVGEKAVKKTEELLNTRLPEDFEKIATENDCGIPHPGRYSFNDGERYLFRMLTILGKSGA
>NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein
MNVKMMRIDLLEPSHYNFRKDLQHGDPEYEKLKRSIEEFGYVEPIIWNEKTGRVVGGHQCLKVMKDQGFENVQVGISGVEGKSSENRGV

Crispr_ID: NZ_CP048104_6

• CRISPR_ID: NZ_CP048104_6
• CRISPR_location: 1702851-1703148
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_CP048104_6

Consensus_repeat	Method
GTTTCAATACCTCATAGGTAAGATCAAAAC	PILER-CR
GTTTTGATCTTACCTATGAGGTATTGAAAC	CRISPRCasFinder
GATCTTACCTATGAGGTATTGAAAC	CRT

spacers of NZ_CP048104_6

>6.1|1702881|37|NZ_CP048104|PILER-CR,CRISPRCasFinder
AAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTC
>6.2|1702948|38|NZ_CP048104|PILER-CR,CRISPRCasFinder
GTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCC
>6.3|1703016|35|NZ_CP048104|PILER-CR,CRISPRCasFinder
CATCTCTCTTTCATGAGAATACCTCCTCTATATTT
>6.4|1703081|38|NZ_CP048104|CRISPRCasFinder
CTAACTTCTTCGAGGTATACCTCTCAGTCGGTTCCCCC
>6.5|1702881|42|NZ_CP048104|CRT
AAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTCGTTTC
>6.6|1702948|43|NZ_CP048104|CRT
GTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCCGTTTA
>6.7|1703016|40|NZ_CP048104|CRT
CATCTCTCTTTCATGAGAATACCTCCTCTATATTTGTTTT
>6.8|1703081|43|NZ_CP048104|CRT
CTAACTTCTTCGAGGTATACCTCTCAGTCGGTTCCCCCGTTTG

CRISPR arrays and Neighbor proteins around NZ_CP048104_6

CRISPR arrays

The CRISPR arrays of NZ_CP048104_6

>merge|NZ_CP048104|6|1702851-1703148|PILER-CR,CRISPRCasFinder,CRT
GTTTTGATCTTACCTATGAGGTATTGAAACAAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTCGTTTCGATCTTACCTATGAGGTATTGAAACGTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCCGTTTAGATCTTACCTATGAGGTATTGAAACCATCTCTCTTTCATGAGAATACCTCCTCTATATTTGTTTTGATCTTACCTATAAAGTATTGAAACCTAACTTCTTCGAGGTATACCTCTCAGTCGGTTCCCCCGTTTGGATCTTACCTATGAGGAAACAAGAA

>NZ_CP048104|6|6|1702851-1703080|PILER-CR
GTTTTGATCTTACCTATGAGGTATTGAAAC	AAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTC
GTTTCGATCTTACCTATGAGGTATTGAAAC	GTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCC
GTTTAGATCTTACCTATGAGGTATTGAAAC	CATCTCTCTTTCATGAGAATACCTCCTCTATATTT
GTTTTGATCTTACCTATAAAGTATTGAAAC

>NZ_CP048104|6|6|1702851-1703148|CRISPRCasFinder
GTTTTGATCTTACCTATGAGGTATTGAAAC	AAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTC
GTTTCGATCTTACCTATGAGGTATTGAAAC	GTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCC
GTTTAGATCTTACCTATGAGGTATTGAAAC	CATCTCTCTTTCATGAGAATACCTCCTCTATATTT
GTTTTGATCTTACCTATAAAGTATTGAAAC	CTAACTTCTTCGAGGTATACCTCTCAGTCGGTTCCCCC
GTTTGGATCTTACCTATGAGGAAACAAGAA

>NZ_CP048104|6|5|1702856-1703148|CRT
GATCTTACCTATGAGGTATTGAAAC	AAGTAGCCCAATCTGCTGTACCACCTGAACCGAATTCGTTTC
GATCTTACCTATGAGGTATTGAAAC	GTCACTGTCTCGATCTTTACCCTGCCAGGACGCTTTCCGTTTA
GATCTTACCTATGAGGTATTGAAAC	CATCTCTCTTTCATGAGAATACCTCCTCTATATTTGTTTT
GATCTTACCTATAAAGTATTGAAAC	CTAACTTCTTCGAGGTATACCTCTCAGTCGGTTCCCCCGTTTG
GATCTTACCTATGAGGAAACAAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213192
NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein	unknown	unknown	gnl|CDD|372502
NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|236841
NZ_CP048104.1|WP_173222184.1|1709233_1709449_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379326
NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|276809
NZ_CP048104.1|WP_173222180.1|1708112_1708712_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease	unknown	unknown	gnl|CDD|372235
NZ_CP048104.1|WP_173222182.1|1708823_1709228_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|319258
NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NZ_CP048104.1|WP_173225404.1|1710810_1712361_+|recombinase-family-protein	unknown	unknown	gnl|CDD|377856
NZ_CP048104.1|WP_173218908.1|1710262_1710499_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173225401.1|1703831_1704299_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein	unknown	unknown	gnl|CDD|212133
NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase	unknown	unknown	gnl|CDD|236199
NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|214864
NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein	unknown	unknown	gnl|CDD|223841

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	1.61271e-57
NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein	gnl|CDD|372502	pfam13157, DUF3992, Protein of unknown function (DUF3992). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 98 and 122 amino acids in length. There is a single completely conserved residue T that may be functionally important.	0.00148105
NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	1.91068e-15
NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase	gnl|CDD|236841	PRK11088, rrmA, 23S rRNA methyltransferase A; Provisional.	1.4888e-43
NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase	gnl|CDD|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.98958e-15
NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.52613e-12
NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease	gnl|CDD|372235	pfam12639, Colicin-DNase, DNase/tRNase domain of colicin-like bacteriocin. Colicin-like bacteriocins are complex structures with an N-terminal beta-barrel translocation domain (pfam09000), a long double-alpha-helical receptor-binding domain (pfam11570) and this C-terminal RNAse/DNase domain with endonuclease activity. Their competitor bacteriocidal action is by a process that involves binding to a surface receptor, entering the cell, and, finally, killing it. The lethal action of colicin E3 is a specific cleavage in the ribosomal decoding A site. The crystal structure of colicin E3 reveals a Y-shaped molecule with the receptor binding domain forming a 100 Angstrom long stalk and the two globular heads of the translocation domain and this catalytic domain comprising the two arms.	2.24887e-11
NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein	gnl|CDD|319258	cd16401, ParB_N_like_MT, ParB N-terminal-like domain, some attached to C-terminal S-adenosylmethionine-dependent methyltransferase domain. This family represents domains related to the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system, fused to a variety of C-terminal domains, including S-adenosylmethionine-dependent methyltransferase-like domains. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	3.30541e-28
NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67125e-61
NZ_CP048104.1|WP_173225404.1|1710810_1712361_+|recombinase-family-protein	gnl|CDD|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	8.56864e-27
NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein	gnl|CDD|212133	cd11523, NTP-PPase, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily. This superfamily contains enzymes that hydrolyze the alpha-beta phosphodiester bond of all canonical NTPs into monophosphate derivatives and pyrophosphate (PPi). Divalent ions, such as Mg2+ ion(s), are essential to activate a proposed water nucleophile and stabilize the charged intermediates to facilitate catalysis. These enzymes share a conserved divalent ion-binding motif EXX[E/D] in their active sites. They also share a highly conserved four-helix bundle, where one face forms the active site, while the other participates in oligomer assembly. The four-helix bundle consists of two central antiparallel alpha-helices that can be contained within a single protomer or form upon dimerization. The superfamily members include dimeric dUTP pyrophosphatases (dUTPases; EC 3.6.1.23), the nonspecific NTP-PPase MazG proteins, HisE-encoded phosphoribosyl ATP pyrophosphohydolase (PRA-PH), fungal histidine biosynthesis trifunctional proteins, and several uncharacterized protein families.	1.62942e-15
NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase	gnl|CDD|236199	PRK08244, PRK08244, monooxygenase.	0
NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	1.12714e-65
NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein	gnl|CDD|214864	smart00860, SMI1_KNR4, SMI1 / KNR4 family. Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.	1.88517e-05
NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein	gnl|CDD|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	4.73994e-14

Protein sequences

>NZ_CP048104.1|WP_173222172.1|1700712_1702218_-|monooxygenase
MDFEVIVVGGGPVGMMLASELALAKVKVCVLENLKETTPYSRALTVHPRTLEIFDSRGLKEKIMSKGMPISKGHFAVLDTPLDFSTLDSTSNYTVFIPQHDTEIELEKWARSLGVEIRRGEKVVSVRQDHQGVEVVSVSSNGDSVLSAAYVVGADGGGSIVRKQANIPFVGKNSTFTALMGDVVLSNPPESNVISRFSERGLVMVAPVNAQLHRVVMVDPERMDVPKEEPVTLEELRSGLVRILGSDLGITEPFWMSRFGNATLQVERYREGRVLLAGDAAHIHFPAGGQGLNVGLQEAMNLGWKLAAEIHGWAPDWLLDSYHEERFPVSTAMLKNTEVQTLLFEFSPRMIELRNMLSSMLKIPESNYLLSTQISGFNVKYETDAKALPHALNGCRFTELKLRLENGTIRNAYELFHSGTFLLLHLASDECMTYAVDWSRYKHVQVVRATLAEEAPDWKDVHTALIRPDGYIAWAVSKSELGRMETIKKGISRWCGGHGIS
>NZ_CP048104.1|WP_173225398.1|1699745_1700543_-|SAM-dependent-methyltransferase
MNKRIKGAEYLSNFESIFKCPICDSPMNVFELKSLICSNNHTFDFTKQGYINLTTYPVKTRYSKDLFEARRKLIAEDGFFEPLSQAIAEIINKHTAVKKGTISLIDMGCGEGSGVLVATKSYTHKIWAVADLSKTPFKDKQFDVILNILSPSNYKEFNRLLKADGFVVKVVPQSGYLKELREVIFDKPEKQSYSNVDTVERFNENFQLVDRSRLCYTVTLDNPSIQSLVQMTPLSWATTDKQVKSFLEGDSVQITFDLEILIGKK
>NZ_CP048104.1|WP_173222170.1|1696692_1698027_+|helix-turn-helix-transcriptional-regulator
MTHVDVNEIGEIIRKVRKEKGLRLEDLADENISPATISNLERGVPHVKHDKLTYLMEKLNIKINQIPDLIMKEHQKLQHLQFNLFAIESLRDNGYPEEALCKIDELDIDDSNPYIAHIHLLKGKCYNSLGKWKKAERAFFNAIRHMNNNHSDKQSNIEAASFTGLSLCSFFQNNLDQALVYTESGLEAFVEDGERSQYKYVLFQNKAMFLEKQGRPIEALKVVQDSWNFLPKIEQIEVILGFYWLRAELLRHTGLYQDAIHYAKEGLEKARFNHEYCRQFDLWTVLGSTYMALKEWDQAESCFELALKLKDRFPNGEILTSAYARLGILYMYQKKWNEAKDAILKAIQKGEEFNDAPRLAYAFIVMGHYYQKRKEFNEAITYYQRSLDLARNHNYRQKERLALHLLAECLEEIDEQEFQSCVRNMYIAQKNIYHEEGIALEKME
>NZ_CP048104.1|WP_173222168.1|1695513_1695915_+|hypothetical-protein
MGGTLIRGKANYRVQSANLGKPKYLRQNQIYFYSKSRSWDDQLAALRRIRPVAAVIPHHLASHLPKEIAVITHSQVPSAYWRLALWNFKKLPVHVVAITGSAGKSTTTEMVDSILKQSKQVVKTQGNLNTFMF
>NZ_CP048104.1|WP_173222166.1|1694045_1695200_-|acyl-CoA/acyl-ACP-dehydrogenase
MSSLFVKTKRQQELYREVSQLADRFSESSAHIDKHGIFPTDQINALRNSGYSGLVVPKKYGGEGITVYDMVLLQERLAKGDAAIALCIGWHLGVLADIAEKKRWNEEVFEFIAGETLKGALVNRAATEAQTGSPTRGGRPQTHAVKQNGKWIINGRKTFTTMAPVLDYFLVTAWIEEKQAVGEFLLHKDLKGIKIEETWDMIAMRGTGSHDLILTDVEVDRSMLVEVISKPRSAQVNGWLLHIPACYLGIAGSARDYAVEFANQYSPNSLNGPIKELPHIQSLVGKMELELLQARHFLFSVAEAYCISENRHLLGSELAAVKYTVTNTAISVVDKAMRIVGAKSLHRTNPLQRYYRDVRAGLHNPPMDDATLVKLAHNAFNLTN
>NZ_CP048104.1|WP_173222164.1|1693459_1693945_-|ABC-transporter-ATP-binding-protein
MLKSLIGLVKKTEGIIEINNKQIGSTTTFDLFADIGYVFQNPDTQLFCHTVEEKIQFGLKNRQIQPDELQERTERILEIIGLSHVRLAHPFSLSRGQRQKLAVATMLITNPSIILLDEPTTGQDEGSLLSLLTLLRKLVEENKTTIVMITHDMEVVAKYAT
>NZ_CP048104.1|WP_173222162.1|1692415_1692742_-|hypothetical-protein
MNTTTFQKWVEEFYDGRGWSHYDPFIRVGFLMEEVGEVARVVRAIEIGRDRPDEKRMSEDVLKEELTEELGDVLANLIILAEKYDIDLEEIMNHHVQKLTKRFTEEQV
>NZ_CP048104.1|WP_173222160.1|1691541_1692051_+|DUF3992-domain-containing-protein
MYECKVRNRNTRNRRLKKRKIKCKGPQHRKCMHKFRKKPAKKQKGTPVSHKLCGNILLNDQHTLEIMEIWKKRIKQDATLTLSVFNSTGSTAPLQVLVNRKEEKSDTFTVPPGNTLSTTVCNVDSIRVFRIDKGKVEGKFCLDIVFPFSAKKQIRSHSIRFSQEELAGV
>NZ_CP048104.1|WP_173222159.1|1689813_1690494_-|N-acetylmuramoyl-L-alanine-amidase
MTKKIFIDPGHGGSDSGATGNGLKEKDLNLAIALEAKKVIQDEYTDHSIKMSREKDETVSLTQRTDAANRWGADFFLSIHINAGGGTGFESYRYVEKGSDTTMTVQKHVHAFILSASGWKDRGKKWANLHVLRESKMPAVLTENGFIDTDTDAKKLKDPSFVKKLGRAHAEGLAKALGLKRKESDPEPEPGNLYIVQAGAFKDRKNAEVRVKALKEAGFEAFIQIK
>NZ_CP048104.1|WP_173222157.1|1689187_1689709_-|GNAT-family-N-acetyltransferase
MGKITFRRLDESDVFLYREFILTGCRETPLDVGLTEKEWGAKNTYKALEEQFRQHDNNPGCFILGAYDGNKMVGTLGFTRNEPIMRRHIAWIWGVQVDSQYRNQGIAKSLFKEMLIRSRECKGLEQIRLKVRSDNEKAIKVYQSIGFQFIAKEPGVLKWGDRYIDQFWMMMSL
>NZ_CP048104.1|WP_173225401.1|1703831_1704299_-|hypothetical-protein
MSLGYDQDSFEFWLMDMDDAIERLFSLLPSEVTGHLDYSEYSLNHIEKWILDQYMDTNSIIEKSEKMTLDGLARYVGETFRMAFKGKWIISLDDPDKAFHMIPQVIFSDYEVNSISPVTLVTASADRRLGNYLSTVYRNVKQSKKALYKGYFVRV
>NZ_CP048104.1|WP_173222174.1|1704500_1704953_-|SMI1/KNR4-family-protein
MNKINWKYDEGLVGEKAVKKTEELLNTRLPEDFKKIATENDCGVPHPGRYSFNDGVMVFGQLFSIDPKRDNNIVEVTRIGRSEHGMSDNIVAFADDPAGNFLCFDYSQLNNGYPAIIFWDHEIEGGDPETICSTFTELLNMFHEDVDEKK
>NZ_CP048104.1|WP_173222176.1|1705600_1706062_-|SMI1/KNR4-family-protein
MEWLKLDEPLSEREITQVEDQLGLKLPEDYVKWIRQYEGPESDFVSVDVNGEPHDVEGFYGPESLVDEMNLIFESREEYKGHGIIIPFAIDSILSKYCFFYPKGSQEPSGVFFRSRDVDLSDIFEGNDIKKSLYISQTFQGFLDKLYIDEDWI
>NZ_CP048104.1|WP_173222178.1|1706074_1707610_-|HNH-endonuclease
MVASIEQHIACINEESTCQKGGANENKTGSNVKPHDSNPPDNKNGESSFWDTLGNTVSDGWNQTKKVAGDAWGRIKQEVKEETESLKGTSFKERMKKSIQWSLEWIPGISGISTDIKKLTGFNLIEWISENPGSTLLNAAGIALIFVPGGQGAGAATFINIARTLGWGIVGGSGVGGIVAGLTGGDISDGILYGGLAGLVGGGVGGGVYRGAASFFSRYGGSLVQKWLPGSLGGGSGAFADMATFEWLTQGKVDWKKAGLTGAMIGALTFGGGMFLDKAGPAIGQAMKQFGFNVNIGADGTIAMPWVREAEENVRKSSGSGGTQTPFKARKPPKLSQGDPNFSFKSEWDEKTKELWVTTSDGRKFKVNYGEKRNTVETKTTKEGNTYTVSYDGDAFPDFSPYAVKSKNGEPIEIILPDDTLVGPSSDQTRYTTQLLKEKYPNWRTEFGFTESQIASIEKNKGSIGPGIFKNSAEQLTWHHDKETGKLILVPYDLNNTFQHSGGHQFWGSQK
>NZ_CP048104.1|WP_173222180.1|1708112_1708712_+|hypothetical-protein
MAIETGLTEVFLSGAVGALVGAWIGGKTAGREQRRTEVYKMKRKALEDLDGKVMHFYFQFLDGLEYDCFNPSKKRELPNKKTILHLKQLRNVAKQQHNLCYYRGYLDHAETFMIDVFDVADRIFQVIENEQIPSYKELSRAEDVFDEATKAIESVIRELEGEFNPTITSLWKRQKYKISMWKIRRNIKRKEKKQQEQIT
>NZ_CP048104.1|WP_173222182.1|1708823_1709228_-|hypothetical-protein
MIRELRAEVNRLNELVPETEERPLKEEKDSLQVVDGEQEEQDFSGDPIFKGDGNKTNLGVNITKPPRTCWGLWRFRLFFPDGNDIPRLKLIRFTYSLDHIGGERENDLPKLLRKFEETIRFPFGNPFFGELDGF
>NZ_CP048104.1|WP_173222184.1|1709233_1709449_-|hypothetical-protein
MNKINWKYDEGLVGEKAVKKTEELLNTRLPEDFEKIATENDCGIPHPGRYSFNDGERYLFRMLTILGKSGA
>NZ_CP048104.1|WP_173222186.1|1709452_1709722_-|ParB-N-terminal-domain-containing-protein
MNVKMMRIDLLEPSHYNFRKDLQHGDPEYEKLKRSIEEFGYVEPIIWNEKTGRVVGGHQCLKVMKDQGFENVQVGISGVEGKSSENRGV
>NZ_CP048104.1|WP_173218908.1|1710262_1710499_-|hypothetical-protein
MTEPIRHHSHKIQRGDESMKKQEVQPEEIMIGKTKAIIYCGLNGMTSEERREWFEKEKKKGNPVLKQISRAIFDCQRD
>NZ_CP048104.1|WP_173225404.1|1710810_1712361_+|recombinase-family-protein
MQRPHGLDVYVYLRKSRKDIEEENRATDEGRIFDTLERHRNQLMELAKKEQHHILDIYEEVVSGEHLLDRPQIQEMLKMVDNGNCDAVMVMDLDRLGRGDMYDMGMIYRAFQYSETLIITPNEVIDPNAEGAELLFGVKSIISREELKSITKRMQRGRQVSAKEGKSITRKPPFGYLRDENLKLYPDPDHAWIVKRIFEMVAEGKGRSAIAKELTKMGIPTPDRAREWNATTLKNILNNEVYRGHIIWGTKRNVKRNGKYVAKPLPPDQWQRKDNAHEPIISQELWEKAHANYGKNYIPPVHTPRKLTNPLAGLIYCNNCNYAMQYKKDSKNVIQMECRSSKCRGVVRGISFRTLEDRVLEIMEKKIQEFKADEKEAKTKQKEPSVVISLHKKSLEAKEKELKTLYNQKENLHDFLEQGIYDIETFMVRQKKLADRIKETESEMKELQGGIIQKEREEKNRTEFIPKIRTVIDAYQTTEDIEKKNQLMKSVLDRVLYTRPKGSKYREFTIEVHFRF

Crispr_ID: NZ_CP048104_7

• CRISPR_ID: NZ_CP048104_7
• CRISPR_location: 2735034-2735195
• CRISPR_type: TypeI-A
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3,cas6

Consensus repeat of NZ_CP048104_7

Consensus_repeat	Method
TTTCAATCCTCTAA-CGAGGTGCTTTGTATTGTGACA	PILER-CR

spacers of NZ_CP048104_7

>7.1|2735078|35|NZ_CP048104|PILER-CR
ATCGCCTTCCCTATGGCGTAGAGGCATCCATCCGG
>7.2|2735157|29|NZ_CP048104|PILER-CR
AGGACAACCTATAAGGTCTCCTTTCTTCA

CRISPR arrays and Neighbor proteins around NZ_CP048104_7

CRISPR arrays

The CRISPR arrays of NZ_CP048104_7

>merge|NZ_CP048104|7|2735034-2735195|PILER-CR
GGTGCTTTGTATGGTGACAATCGCCTTCCCTATGGCGTAGAGGCATCCATCCGGTTTCAATCCTCTAACCGAGGTGCTTTGTTTTGTGACATACTCCCAGGACAACCTATAAGGTCTCCTTTCTTCATTTCAATCCTCTAACGAGGTGCTTTGTATTGTGAC

>NZ_CP048104|7|7|2735034-2735195|PILER-CR
GGTGCTTTGTATGGTGACAATCGCCTTCCCTATGGCGTAGAGGC	ATCCATCCGGTTTCAATCCTCTAACCGAGGTGCTT
TGTTTTGTGACATACTCCCAGGACAACCTATAAGGTCTCCTTTC	TTCATTTCAATCCTCTAACGAGGTGCTTT
GTATTGTGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)	unknown	unknown	gnl|CDD|237415
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	unknown	unknown	gnl|CDD|225283
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|225918
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl|CDD|225556
NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|187783
NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl|CDD|129801
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP048104.1|WP_173223800.1|2726768_2728061_+|arsenic-transporter	unknown	unknown	gnl|CDD|185342
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	unknown	unknown	gnl|CDD|129802

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6e-19	63.9	0.0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.7e-20	67.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)	gnl|CDD|237415	PRK13530, PRK13530, arsenate reductase (thioredoxin).	4.65085e-87
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.05921e-19
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.08868e-48
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	gnl|CDD|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.39757e-16
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	1.32815e-95
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl|CDD|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.49129e-42
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.70099e-08
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl|CDD|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.24798e-96
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	9.36644e-73
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	5.11079e-51
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.24507e-49
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.71831e-29
NZ_CP048104.1|WP_173223800.1|2726768_2728061_+|arsenic-transporter	gnl|CDD|185342	PRK15445, PRK15445, arsenical efflux pump membrane protein ArsB.	0
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	gnl|CDD|129802	TIGR00719, Probable_L-serine_dehydratase_beta_chain, L-serine dehydratase, iron-sulfur-dependent, beta subunit. This enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.75676e-41

Protein sequences

>NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase
MNVWDLDACGVLEAMGSGKVTSAQAVQGYRDQIERTNPTLNYLVEDRFAKALQEAKECDRRQQEGTGKLWGVPISIKEAYNVAGMKTTGGLFHRKDQVEESDAAVTAKLKAAGAVILGKTNTPTLCFCQESENKLYGRTNNPWNPERTAGGSSSGEGAIIAVGGAAAGIGSDIGGSIRFPSHFNGVVGFKSGHGQVDQQGHFPFVDHPLQERMLGLGPMTKSVRDTRLIYNIIAKTPAPKKEVADYVITFLPQTTYPLSKVTVTLMHQVKAFFNKELETEEAVPPWFDPSALMWQEIMSVDGGEGTAKIAFGDRAARPVWEYLKEITTGKSEWHRHLTWALIGARLFRPGAKRVREIEEILHQGDEELDRYLDKRILVFPVYHCGAPIHGDLYREIFSIRKTFLRYMPYVAYANVWGLPSLTIPVGTDGDGMPISLQLMSRNRNEEALFQLGEIVEKQFRGYLRCDHGEDQ
>NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein
MSQGLKVTDIGKYQRLRETEDLLRRASHGYKPERGTESLQLWHTTNPAGVLTTPSKESEADMSAEVLKAIQDLNKQLAEV
>NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein
MNNKIDHTQNELRNEISTVKSDLKEDVSAIKDNVDHISETVTQLDKTTGILEERTKDIATQAHVSSEIHSTHLKILVWIVGTALTVGAMTVSIVKLL
>NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase
MHPDWQRICNEFLEATSYSLGELEKGWASNYDFSKRPPTYLRYEESLARIPLGTPDFPSSPDLWQLLRERRSKRNFTKTPLTLNELNLLLWGTTGITADMGDYQLRTVPSAGALYPIETYLLVNNVESLDQGLYHLDVENWCLELLKREDVSEVAHLYTEEQEMTRHAAVNFVWTAMVDRTKDKYKERAYRYVWWDAGHVAQNLHITGNALGLGVCTIGHWFDKNMNDYLGIDGISHFSVLMASAGKVTGGHWLEDRRPVVSDSGE
>NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator
MTLAQLQVFITAAESGSFTRAADSLGYTQSAVSQMVNSLEKELGVQLFHRSRSGIATTGIGERMLSHARHILQITSCMQQEAASAQGLEEGVLRIGSIPSVAAKVLPSLIGSFRRRFPQVDIVLFEGEHEEIHNWITSSVVDVGFTSMPDKELHTIPLLWDEMRVILPDQHSLKDEPFLTFSQIRDRCFIMPKDHSIKQLLRANGITPDVTFEVRDVTTILAMVQEWIGVTIVPELYLPEVKPKVVALPLRPAIKRELVLVVRNLQSVSPITAEFIVHSQRYVSAA
>NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein
MFKLLSVGNPLGLDQSVTVGIISGKDRPLHIGDRFFGNVVQTDAAINPGNSGGPLINMLGEVIAVNTLMAYPSQGISFAISIDEIKPLIRRYQ
>NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein
MVLKPHVAINVKELDASIEFYRHLFGEEPAKVRPGYGKFDLDEPALNFTLNEGGEITGGINHLGIQVGSTEAVIAAKERLKNAGLASFDEMDTTCCYARQDKIWVTSPDGHQWEVFFVKEDADSFGQSPAIPEADSPCCTPK
>NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator
MACCTSEQLSLIARALSDPIRYQILDLIARGNSEDAAVCCTAEMCVCDIQEVLDLKQSKVSYHLKELKNAGLLHERKQGKWNYYSVNQSMLKAFCDELSRRFHLPDEGVTP
>NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)
MEGFTVNKKKTIYFLCTGNSCRSQMAEGFGKQILRDRFNVYSAGIEAHGLNPKAVKVMAEKGIDISDQTSNVIDPEILNHADYVITLCGDANDKCPLTPPHVNRQHWGFDDPAKAQGTEEEVWAVFQRVRDQVEERIRRFSEETKKD
>NZ_CP048104.1|WP_173223800.1|2726768_2728061_+|arsenic-transporter
MSWIAFMVFAITLVFVIWQPRGLSIGWSATGGALLALLFGVVSLPDVWTVTGIVWNATLAFVAVILISLILDEIGFFEWAALHMARLAGGNGRKMFIYVVLLGAAVAAFFANDGAALILTPIVLAMVRALRFDEKMILAFVMASGFIADTTSLPLVVSNLVNIVSADYFGIGFVEYATRMIVPNFFALGASLLVLFLFFRKSIPKEYELAHLKKPLEAIKDPRLFRLSWIILGFLLAGYLFSESLGVPVSMIAGAAAIWFILAARRSPAIRTKQLIKDAPWAVVVFSIGMYVLVYGLKNAGLTDALARVIQWTADQGLLAGTLGMGFIAAILSSIMNNMPTVMIDALAINSTTTDGLMREALVYANVIGSDLGPKITPIGSLATLLWLHVLTRKGVKITWGYYFKVGILLTIPTLLITLLGLYAWLMLIH
>NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYQLCLSVKPRSKVKNRWVLSRRLHGFILRMIKMQDPQLSEWLHNRKDRQFFSCHSSFQEKEWYIQTPSREIVRCLQQSLLSHPVIDLRDWTGEIQEIHCYSYTVKDMLQNFSPKVTFQFHTPTTFYQWGNYYPMPELQRLFASGAKSYEMDGNIPIPWEEIEPLTRRVRIEHLSITTQRADFGKFKVVGFCGTLAFSLKALSAEEQKKMWLLANYGSLMGFGYKTAWGLGQTSIREQLRTPPASESTQGVFGKQEPLEIQGI
>NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein
MMIEEEWMVRVVIKGSPFYPFDKDESLEEGGFYTGEWCFRLEKEQHSIL
>NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein
MTSYILPVLKKSILMTFRIYLSIVFLIYGLAKFWPGQFPNGTHVVYDSSVNSPFDLAWAFFGHSRMYELMIGAGEVTAAILLLIPRTRTLGALIYFPIALNVMMVNYFFEIGVLDLSTVMVVMAGCLLLADFKKISVLWSPDLQERGRNKE
>NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MESHPFKTKEGPVILFDGVCNLCNSWVQFVIRRDSQVRFRFASLQSPVGSSLRTSCGIPQNSDSIVLVEEQRCFHQSSAVLRICKGLDGFWKWLYIFILIPKPLRDWVYRWVARNRYRFFGKRDACMIPTKNMRSRFLDEG
>NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter
MRFSTLLTLTLSIFTVGIVELIIAGILELVAQDLQVSPSLAGQLITLYAFTFAIASPVLMTLTANVERRLLLILSLIVFILTNLATAFSSSWMAISVARVATAMSAAVYVVTALGVTAKLADESFRGRALGYVYMGFSAANIFGVPLGTAIGVWFGWRNTFIMIAGLGFLSLFGIWKTIPSLEGQKSSSLGEALKVAGNPRILGMLGVTSFLLAGHYMVYAYISPFLTTAGYSLTAVSLFLLLAGIVGTLGTSLGGIMTDRIGAVPSLRIAVFLFIGSLGLLPFSLDIMWITLILFAIWNLSIWSINSPSQYCLIQLSPQSSDLALSLNMSALNIGIGLGSAMGGLLLLKFPVIYSAWAGCALGVIGLLCFSFAKKALPASS
>NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
METLLQHCQDQGKSIGEVMLDYEVKKSGRSREKVLEMMVERLKKMKEAVDQGSDDPSPAPSGISGGDAKIMGQYRKEDHPFSGPLIFDAMRFAFATSEHNARMGVIVATPTAGSAGVLPGCLFSLYDNAGYSFDSLVMGLMTASAIGFVIANRSFVSGAAGGCQAEVGSAVAMAAAAIVELKGGKPAQAIHAAAISLKSMLGLVCDPVAGLVEVPCIKRNAIGTAIAFSAADIAMAGVESRIPCDEVIATMYDIGRSMPRTLRETSLGGLAVTPTGKKVKERLFQQNKDEARRKTESQPCRESNVD
>NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein
MNYQSCFDIIGPIMVGPSSSHTAGVVSIGKFVHDYMGGPPERSEIVFYDSFAETYQGHGTDKAIVGGLLGMKTDDIGIRHALEEASRRNVIINFCLEGSCPHYDHPNTVMTWNERNGEIFSIGGVSLGGGVSKIFLIDGLKVDLPLNEPVDMDELRNKARKKLSKDAAVAVKEG
>NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase
MSLSVHDPDLFQAIESERKRQHQTLELIASENFVSQDVLEAMGTELTNKYAEGYPGKRYYGGCEFVDVVENLAIERLKKLFGAGFANVQPHSGSQANTAVYFSLLQPGDTIMGMNLSHGGHLTHGSPVSISGKWFHVVDYGVKEDTHRIDYDQVEAIAKRERPKLIIAGTSAYPRQIDFSKFRDIADQVGAYLMVDMAHIAGLVAAGIHPSPIPHADVVTSTTHKTLRGPRGGVILTNDEDLAKKMNKAVFPGTQGGPLMHIIAAKAVAFKEALSPEFKEYAHQVVKNAQTLAETLKQEGATLVSGGTDNHLLLLDVRPWELTGKEAEKWLEDAGITVNKNTIPYDPASPFVTSGIRIGTAAVTSRGMGTKEMKHIGELIATVLKSKGEPEILRQVRTSVRELCEHSPLHVSAVGG
>NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein
MAKATTNIVHLKPGEQEEPTQTVEDLLRILAEHRESVEKSVKLLEQLHQKGLLDLAIAGLEQGDHVLDVLVKQASRPATVNGIQTVIALAQLSLALDPQKVSQLGKGVISGMEAAATNKGPQIDGMLDLLKALRDPDVARGLSAMMAILKGLGSSLSTSPGEEKQ
>NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha
MSEETQIKVRLDGKEVRIKPGTTVLQTILEERDFPHVCYHPALGPIETCDTCITEVDGKLVRACSTEARQGMEILTFSEASRKARKEGMDRLLHNHELYCTVCDNNNGNCVVHNTAMMMEVEHQKYPFSPKPYPEDNSNPFYRYDPDQCILCGRCVEACQNLQVSEVLSIDWKRERPRVIWDQDVPINESSCVSCGHCVTVCPCNALMEKSMLGEAGFLTGIPTPTLESMIDLTKEVEPGYSSIFAISEMEEKLRESRIKKTKTVCTYCGVGCSFDVWTKDRKILKVEPQMEAPANQISTCIKGKFGWDFVNSSERLVKPLIRKGDTFYPAEWDEALNYVAKRLSSIREEHGPDAIGCISSSKCTNEENYLMQKFARSVIGTNNIDNCSRYCQSPATFAMRQTMGYGGDSGSITDIAATDLVIIIGANPAESHPVLSTRVRRAQKKNGQKLIVADLRKNGMAERADVWLHPKPGSDLIWISAVTKYLIDQGWYDQTFVKERVRGFTDYRNSLERYTLEYAEEVSGIKREQLIQTAEMIRDADRMCLLWAMGVTQHMGGSDTSTAICNLALVTGQVGRPGTGVYPLRGHNNVQGAGDFGCAPDVLPGYESVWDEEVRAKYEQAWNVKLPTTHGSDNHLMVEKIHKGELKALYLKGEEMALVDSNANHVTGAFEKLEFFVVQDVFFSKTAQYADVIFPASPSLEKEGTFTNTERRIQRLYQVLEPLGDSKPDWQIITELANRMGAGWSYEHPREILHEAVSLATLMKGVTYERLEGYHSLQWPVAPDGTDTPLLYTDGFPFDDGKARLVPVEWTHPLELADEYDLHLNNGRILEHFHEGNLTYRVEGIQEKVPTAYVEVSRDLAKERELESGRMVRLVSPYGAVKVPVVVTDRVKGKELYLPMHTTNAEEAVNFLTSSYHDRQTHTPAYKEMSVRMEVLGEKKDSPMKRGNYRLGHPNPQPGVQVEEKWKRDDYEPLVSED

Crispr_ID: NZ_CP048104_8

• CRISPR_ID: NZ_CP048104_8
• CRISPR_location: 2736934-2737102
• CRISPR_type: TypeI-A
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas6,csa3

Consensus repeat of NZ_CP048104_8

Consensus_repeat	Method
GTTTCAATCCTCTAACCGAGGTG	CRISPRCasFinder

spacers of NZ_CP048104_8

>8.1|2736957|51|NZ_CP048104|CRISPRCasFinder
CTTTGCATTGTGACCACAGGTGGAGGCTGTTCCTGAGAAAGTTAGAAAAGA
>8.2|2737031|48|NZ_CP048104|CRISPRCasFinder
CTTTATATTGTGACCGATAAGGTTTTCGAGATACCAAATGAATCCGGT

CRISPR arrays and Neighbor proteins around NZ_CP048104_8

CRISPR arrays

The CRISPR arrays of NZ_CP048104_8

>merge|NZ_CP048104|8|2736934-2737102|CRISPRCasFinder
GTTTAAATCCTCTAACAGAGGTGCTTTGCATTGTGACCACAGGTGGAGGCTGTTCCTGAGAAAGTTAGAAAAGAGTTTCAATCCTCTAACCGAGGTGCTTTATATTGTGACCGATAAGGTTTTCGAGATACCAAATGAATCCGGTGTTTCAATCCTCTAACCGAGGTGC

>NZ_CP048104|8|7|2736934-2737102|CRISPRCasFinder
GTTTAAATCCTCTAACAGAGGTG	CTTTGCATTGTGACCACAGGTGGAGGCTGTTCCTGAGAAAGTTAGAAAAGA
GTTTCAATCCTCTAACCGAGGTG	CTTTATATTGTGACCGATAAGGTTTTCGAGATACCAAATGAATCCGGT
GTTTCAATCCTCTAACCGAGGTGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)	unknown	unknown	gnl|CDD|237415
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	unknown	unknown	gnl|CDD|129802
NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	unknown	unknown	gnl|CDD|225283
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl|CDD|225556
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341286
NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|187783
NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl|CDD|129801
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|225918
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6e-19	63.9	0.0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.7e-20	67.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)	gnl|CDD|237415	PRK13530, PRK13530, arsenate reductase (thioredoxin).	4.65085e-87
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.05921e-19
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.08868e-48
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	gnl|CDD|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.39757e-16
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	1.32815e-95
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl|CDD|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.49129e-42
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	gnl|CDD|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	8.53596e-156
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.70099e-08
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl|CDD|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.24798e-96
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	9.36644e-73
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	5.11079e-51
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.24507e-49
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.71831e-29
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	gnl|CDD|129802	TIGR00719, Probable_L-serine_dehydratase_beta_chain, L-serine dehydratase, iron-sulfur-dependent, beta subunit. This enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.75676e-41

Protein sequences

>NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYQLCLSVKPRSKVKNRWVLSRRLHGFILRMIKMQDPQLSEWLHNRKDRQFFSCHSSFQEKEWYIQTPSREIVRCLQQSLLSHPVIDLRDWTGEIQEIHCYSYTVKDMLQNFSPKVTFQFHTPTTFYQWGNYYPMPELQRLFASGAKSYEMDGNIPIPWEEIEPLTRRVRIEHLSITTQRADFGKFKVVGFCGTLAFSLKALSAEEQKKMWLLANYGSLMGFGYKTAWGLGQTSIREQLRTPPASESTQGVFGKQEPLEIQGI
>NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase
MNVWDLDACGVLEAMGSGKVTSAQAVQGYRDQIERTNPTLNYLVEDRFAKALQEAKECDRRQQEGTGKLWGVPISIKEAYNVAGMKTTGGLFHRKDQVEESDAAVTAKLKAAGAVILGKTNTPTLCFCQESENKLYGRTNNPWNPERTAGGSSSGEGAIIAVGGAAAGIGSDIGGSIRFPSHFNGVVGFKSGHGQVDQQGHFPFVDHPLQERMLGLGPMTKSVRDTRLIYNIIAKTPAPKKEVADYVITFLPQTTYPLSKVTVTLMHQVKAFFNKELETEEAVPPWFDPSALMWQEIMSVDGGEGTAKIAFGDRAARPVWEYLKEITTGKSEWHRHLTWALIGARLFRPGAKRVREIEEILHQGDEELDRYLDKRILVFPVYHCGAPIHGDLYREIFSIRKTFLRYMPYVAYANVWGLPSLTIPVGTDGDGMPISLQLMSRNRNEEALFQLGEIVEKQFRGYLRCDHGEDQ
>NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein
MSQGLKVTDIGKYQRLRETEDLLRRASHGYKPERGTESLQLWHTTNPAGVLTTPSKESEADMSAEVLKAIQDLNKQLAEV
>NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein
MNNKIDHTQNELRNEISTVKSDLKEDVSAIKDNVDHISETVTQLDKTTGILEERTKDIATQAHVSSEIHSTHLKILVWIVGTALTVGAMTVSIVKLL
>NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase
MHPDWQRICNEFLEATSYSLGELEKGWASNYDFSKRPPTYLRYEESLARIPLGTPDFPSSPDLWQLLRERRSKRNFTKTPLTLNELNLLLWGTTGITADMGDYQLRTVPSAGALYPIETYLLVNNVESLDQGLYHLDVENWCLELLKREDVSEVAHLYTEEQEMTRHAAVNFVWTAMVDRTKDKYKERAYRYVWWDAGHVAQNLHITGNALGLGVCTIGHWFDKNMNDYLGIDGISHFSVLMASAGKVTGGHWLEDRRPVVSDSGE
>NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator
MTLAQLQVFITAAESGSFTRAADSLGYTQSAVSQMVNSLEKELGVQLFHRSRSGIATTGIGERMLSHARHILQITSCMQQEAASAQGLEEGVLRIGSIPSVAAKVLPSLIGSFRRRFPQVDIVLFEGEHEEIHNWITSSVVDVGFTSMPDKELHTIPLLWDEMRVILPDQHSLKDEPFLTFSQIRDRCFIMPKDHSIKQLLRANGITPDVTFEVRDVTTILAMVQEWIGVTIVPELYLPEVKPKVVALPLRPAIKRELVLVVRNLQSVSPITAEFIVHSQRYVSAA
>NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein
MFKLLSVGNPLGLDQSVTVGIISGKDRPLHIGDRFFGNVVQTDAAINPGNSGGPLINMLGEVIAVNTLMAYPSQGISFAISIDEIKPLIRRYQ
>NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein
MVLKPHVAINVKELDASIEFYRHLFGEEPAKVRPGYGKFDLDEPALNFTLNEGGEITGGINHLGIQVGSTEAVIAAKERLKNAGLASFDEMDTTCCYARQDKIWVTSPDGHQWEVFFVKEDADSFGQSPAIPEADSPCCTPK
>NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator
MACCTSEQLSLIARALSDPIRYQILDLIARGNSEDAAVCCTAEMCVCDIQEVLDLKQSKVSYHLKELKNAGLLHERKQGKWNYYSVNQSMLKAFCDELSRRFHLPDEGVTP
>NZ_CP048104.1|WP_173223802.1|2728068_2728512_+|arsenate-reductase-(thioredoxin)
MEGFTVNKKKTIYFLCTGNSCRSQMAEGFGKQILRDRFNVYSAGIEAHGLNPKAVKVMAEKGIDISDQTSNVIDPEILNHADYVITLCGDANDKCPLTPPHVNRQHWGFDDPAKAQGTEEEVWAVFQRVRDQVEERIRRFSEETKKD
>NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein
MMIEEEWMVRVVIKGSPFYPFDKDESLEEGGFYTGEWCFRLEKEQHSIL
>NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein
MTSYILPVLKKSILMTFRIYLSIVFLIYGLAKFWPGQFPNGTHVVYDSSVNSPFDLAWAFFGHSRMYELMIGAGEVTAAILLLIPRTRTLGALIYFPIALNVMMVNYFFEIGVLDLSTVMVVMAGCLLLADFKKISVLWSPDLQERGRNKE
>NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MESHPFKTKEGPVILFDGVCNLCNSWVQFVIRRDSQVRFRFASLQSPVGSSLRTSCGIPQNSDSIVLVEEQRCFHQSSAVLRICKGLDGFWKWLYIFILIPKPLRDWVYRWVARNRYRFFGKRDACMIPTKNMRSRFLDEG
>NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter
MRFSTLLTLTLSIFTVGIVELIIAGILELVAQDLQVSPSLAGQLITLYAFTFAIASPVLMTLTANVERRLLLILSLIVFILTNLATAFSSSWMAISVARVATAMSAAVYVVTALGVTAKLADESFRGRALGYVYMGFSAANIFGVPLGTAIGVWFGWRNTFIMIAGLGFLSLFGIWKTIPSLEGQKSSSLGEALKVAGNPRILGMLGVTSFLLAGHYMVYAYISPFLTTAGYSLTAVSLFLLLAGIVGTLGTSLGGIMTDRIGAVPSLRIAVFLFIGSLGLLPFSLDIMWITLILFAIWNLSIWSINSPSQYCLIQLSPQSSDLALSLNMSALNIGIGLGSAMGGLLLLKFPVIYSAWAGCALGVIGLLCFSFAKKALPASS
>NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
METLLQHCQDQGKSIGEVMLDYEVKKSGRSREKVLEMMVERLKKMKEAVDQGSDDPSPAPSGISGGDAKIMGQYRKEDHPFSGPLIFDAMRFAFATSEHNARMGVIVATPTAGSAGVLPGCLFSLYDNAGYSFDSLVMGLMTASAIGFVIANRSFVSGAAGGCQAEVGSAVAMAAAAIVELKGGKPAQAIHAAAISLKSMLGLVCDPVAGLVEVPCIKRNAIGTAIAFSAADIAMAGVESRIPCDEVIATMYDIGRSMPRTLRETSLGGLAVTPTGKKVKERLFQQNKDEARRKTESQPCRESNVD
>NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein
MNYQSCFDIIGPIMVGPSSSHTAGVVSIGKFVHDYMGGPPERSEIVFYDSFAETYQGHGTDKAIVGGLLGMKTDDIGIRHALEEASRRNVIINFCLEGSCPHYDHPNTVMTWNERNGEIFSIGGVSLGGGVSKIFLIDGLKVDLPLNEPVDMDELRNKARKKLSKDAAVAVKEG
>NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase
MSLSVHDPDLFQAIESERKRQHQTLELIASENFVSQDVLEAMGTELTNKYAEGYPGKRYYGGCEFVDVVENLAIERLKKLFGAGFANVQPHSGSQANTAVYFSLLQPGDTIMGMNLSHGGHLTHGSPVSISGKWFHVVDYGVKEDTHRIDYDQVEAIAKRERPKLIIAGTSAYPRQIDFSKFRDIADQVGAYLMVDMAHIAGLVAAGIHPSPIPHADVVTSTTHKTLRGPRGGVILTNDEDLAKKMNKAVFPGTQGGPLMHIIAAKAVAFKEALSPEFKEYAHQVVKNAQTLAETLKQEGATLVSGGTDNHLLLLDVRPWELTGKEAEKWLEDAGITVNKNTIPYDPASPFVTSGIRIGTAAVTSRGMGTKEMKHIGELIATVLKSKGEPEILRQVRTSVRELCEHSPLHVSAVGG
>NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein
MAKATTNIVHLKPGEQEEPTQTVEDLLRILAEHRESVEKSVKLLEQLHQKGLLDLAIAGLEQGDHVLDVLVKQASRPATVNGIQTVIALAQLSLALDPQKVSQLGKGVISGMEAAATNKGPQIDGMLDLLKALRDPDVARGLSAMMAILKGLGSSLSTSPGEEKQ
>NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha
MSEETQIKVRLDGKEVRIKPGTTVLQTILEERDFPHVCYHPALGPIETCDTCITEVDGKLVRACSTEARQGMEILTFSEASRKARKEGMDRLLHNHELYCTVCDNNNGNCVVHNTAMMMEVEHQKYPFSPKPYPEDNSNPFYRYDPDQCILCGRCVEACQNLQVSEVLSIDWKRERPRVIWDQDVPINESSCVSCGHCVTVCPCNALMEKSMLGEAGFLTGIPTPTLESMIDLTKEVEPGYSSIFAISEMEEKLRESRIKKTKTVCTYCGVGCSFDVWTKDRKILKVEPQMEAPANQISTCIKGKFGWDFVNSSERLVKPLIRKGDTFYPAEWDEALNYVAKRLSSIREEHGPDAIGCISSSKCTNEENYLMQKFARSVIGTNNIDNCSRYCQSPATFAMRQTMGYGGDSGSITDIAATDLVIIIGANPAESHPVLSTRVRRAQKKNGQKLIVADLRKNGMAERADVWLHPKPGSDLIWISAVTKYLIDQGWYDQTFVKERVRGFTDYRNSLERYTLEYAEEVSGIKREQLIQTAEMIRDADRMCLLWAMGVTQHMGGSDTSTAICNLALVTGQVGRPGTGVYPLRGHNNVQGAGDFGCAPDVLPGYESVWDEEVRAKYEQAWNVKLPTTHGSDNHLMVEKIHKGELKALYLKGEEMALVDSNANHVTGAFEKLEFFVVQDVFFSKTAQYADVIFPASPSLEKEGTFTNTERRIQRLYQVLEPLGDSKPDWQIITELANRMGAGWSYEHPREILHEAVSLATLMKGVTYERLEGYHSLQWPVAPDGTDTPLLYTDGFPFDDGKARLVPVEWTHPLELADEYDLHLNNGRILEHFHEGNLTYRVEGIQEKVPTAYVEVSRDLAKERELESGRMVRLVSPYGAVKVPVVVTDRVKGKELYLPMHTTNAEEAVNFLTSSYHDRQTHTPAYKEMSVRMEVLGEKKDSPMKRGNYRLGHPNPQPGVQVEEKWKRDDYEPLVSED
>NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein
MVTIGNLIKSRASLTPDLEAVVCENRRIGYRDYNIMINQLADYLLERNIQKGDRIALLCHNHSSFPLIYLAAAKIGAITVPLNWRAKPDEIRWMLEDCEPKILFYDDLFRPFLSSLEDLSFLETTIPVGDSEETNRFFENLFLHRRDQEPDRTVRSHDPALIIYTSGTTGKPKGVVCTHQNVYTAGLGNVNTLDLWMGDRFLFVTPLFHISGMMFIINAIIRGFTLVLNPRFDPVHIWDLIEQEKITGMMSVPSMLSFMLETVKTRNQVASSLRSILSGGSLVPEKLIRDFYELGYPVSQVYGATEYTGAITYWMPHMDIQRCDSVGKGLYLTEIKVIDPISGNGLPPGEIGEILCRGPQIFAGYWNRKEESDQVLKNGWYHTRDVGKLDSDGYLYVIDRLRDMIIVSGEKVFPAQVEAIINQLEEVEEVAVVGVQHDVWGELSKAYVVKKDTASSLSESEIIQHTRRQLADYNLHEVEFVKELPKNGMGKVLKYLLREYANQSAS

Crispr_ID: NZ_CP048104_10

• CRISPR_ID: NZ_CP048104_10
• CRISPR_location: 2738482-2738742
• CRISPR_type: TypeI-A
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas6,csa3

Consensus repeat of NZ_CP048104_10

Consensus_repeat	Method
GTTTCAATCCTCTAACCGAGGTG	CRISPRCasFinder
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACG	PILER-CR

spacers of NZ_CP048104_10

>10.1|2738505|52|NZ_CP048104|CRISPRCasFinder
CTTGGTATTGTGACTCATGGAATCTTTCGATATAGGAGACCCTGTCCTTATG
>10.2|2738580|52|NZ_CP048104|CRISPRCasFinder
CTTGGTATTGTGACGGGACGGGGCCAAACAGTTGAAGTACTACCCGAACCTT
>10.3|2738655|50|NZ_CP048104|CRISPRCasFinder
CTTTGTATTGTGACAACCTCGAAGGTGATGAAGCAAGTTTCCAATGTCGT
>10.4|2738595|37|NZ_CP048104|PILER-CR
GGACGGGGCCAAACAGTTGAAGTACTACCCGAACCTT
>10.5|2738670|35|NZ_CP048104|PILER-CR
ACCTCGAAGGTGATGAAGCAAGTTTCCAATGTCGT

CRISPR arrays and Neighbor proteins around NZ_CP048104_10

CRISPR arrays

The CRISPR arrays of NZ_CP048104_10

>merge|NZ_CP048104|10|2738482-2738742|CRISPRCasFinder,PILER-CR
TACTCAGTCCTCAGACTGAGGTGCTTGGTATTGTGACTCATGGAATCTTTCGATATAGGAGACCCTGTCCTTATGGTTTCAATCCTCTAACCGAGGGGCTTGGTATTGTGACGGGACGGGGCCAAACAGTTGAAGTACTACCCGAACCTTGTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACAACCTCGAAGGTGATGAAGCAAGTTTCCAATGTCGTGTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACG

>NZ_CP048104|10|9|2738482-2738727|CRISPRCasFinder
TACTCAGTCCTCAGACTGAGGTG	CTTGGTATTGTGACTCATGGAATCTTTCGATATAGGAGACCCTGTCCTTATG
GTTTCAATCCTCTAACCGAGGGG	CTTGGTATTGTGACGGGACGGGGCCAAACAGTTGAAGTACTACCCGAACCTT
GTTTCAATCCTCTAACCGAGGTG	CTTTGTATTGTGACAACCTCGAAGGTGATGAAGCAAGTTTCCAATGTCGT
GTTTCAATCCTCTAACCGAGGTG

>NZ_CP048104|10|9|2738557-2738742|PILER-CR
GTTTCAATCCTCTAACCGAGGGGCTTGGTATTGTGACG	GGACGGGGCCAAACAGTTGAAGTACTACCCGAACCTT
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACA	ACCTCGAAGGTGATGAAGCAAGTTTCCAATGTCGT
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|225918
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	unknown	unknown	gnl|CDD|129802
NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	unknown	unknown	gnl|CDD|225283
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl|CDD|225556
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341286
NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|238045
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|187783
NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl|CDD|129801
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6e-19	63.9	0.0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.7e-20	67.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.05921e-19
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.08868e-48
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	gnl|CDD|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.39757e-16
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	1.32815e-95
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl|CDD|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.49129e-42
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	gnl|CDD|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	8.53596e-156
NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.61576e-08
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.70099e-08
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl|CDD|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.24798e-96
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	9.36644e-73
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	5.11079e-51
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.24507e-49
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.71831e-29
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	gnl|CDD|129802	TIGR00719, Probable_L-serine_dehydratase_beta_chain, L-serine dehydratase, iron-sulfur-dependent, beta subunit. This enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.75676e-41

Protein sequences

>NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein
MMIEEEWMVRVVIKGSPFYPFDKDESLEEGGFYTGEWCFRLEKEQHSIL
>NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYQLCLSVKPRSKVKNRWVLSRRLHGFILRMIKMQDPQLSEWLHNRKDRQFFSCHSSFQEKEWYIQTPSREIVRCLQQSLLSHPVIDLRDWTGEIQEIHCYSYTVKDMLQNFSPKVTFQFHTPTTFYQWGNYYPMPELQRLFASGAKSYEMDGNIPIPWEEIEPLTRRVRIEHLSITTQRADFGKFKVVGFCGTLAFSLKALSAEEQKKMWLLANYGSLMGFGYKTAWGLGQTSIREQLRTPPASESTQGVFGKQEPLEIQGI
>NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase
MNVWDLDACGVLEAMGSGKVTSAQAVQGYRDQIERTNPTLNYLVEDRFAKALQEAKECDRRQQEGTGKLWGVPISIKEAYNVAGMKTTGGLFHRKDQVEESDAAVTAKLKAAGAVILGKTNTPTLCFCQESENKLYGRTNNPWNPERTAGGSSSGEGAIIAVGGAAAGIGSDIGGSIRFPSHFNGVVGFKSGHGQVDQQGHFPFVDHPLQERMLGLGPMTKSVRDTRLIYNIIAKTPAPKKEVADYVITFLPQTTYPLSKVTVTLMHQVKAFFNKELETEEAVPPWFDPSALMWQEIMSVDGGEGTAKIAFGDRAARPVWEYLKEITTGKSEWHRHLTWALIGARLFRPGAKRVREIEEILHQGDEELDRYLDKRILVFPVYHCGAPIHGDLYREIFSIRKTFLRYMPYVAYANVWGLPSLTIPVGTDGDGMPISLQLMSRNRNEEALFQLGEIVEKQFRGYLRCDHGEDQ
>NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein
MSQGLKVTDIGKYQRLRETEDLLRRASHGYKPERGTESLQLWHTTNPAGVLTTPSKESEADMSAEVLKAIQDLNKQLAEV
>NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein
MNNKIDHTQNELRNEISTVKSDLKEDVSAIKDNVDHISETVTQLDKTTGILEERTKDIATQAHVSSEIHSTHLKILVWIVGTALTVGAMTVSIVKLL
>NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase
MHPDWQRICNEFLEATSYSLGELEKGWASNYDFSKRPPTYLRYEESLARIPLGTPDFPSSPDLWQLLRERRSKRNFTKTPLTLNELNLLLWGTTGITADMGDYQLRTVPSAGALYPIETYLLVNNVESLDQGLYHLDVENWCLELLKREDVSEVAHLYTEEQEMTRHAAVNFVWTAMVDRTKDKYKERAYRYVWWDAGHVAQNLHITGNALGLGVCTIGHWFDKNMNDYLGIDGISHFSVLMASAGKVTGGHWLEDRRPVVSDSGE
>NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator
MTLAQLQVFITAAESGSFTRAADSLGYTQSAVSQMVNSLEKELGVQLFHRSRSGIATTGIGERMLSHARHILQITSCMQQEAASAQGLEEGVLRIGSIPSVAAKVLPSLIGSFRRRFPQVDIVLFEGEHEEIHNWITSSVVDVGFTSMPDKELHTIPLLWDEMRVILPDQHSLKDEPFLTFSQIRDRCFIMPKDHSIKQLLRANGITPDVTFEVRDVTTILAMVQEWIGVTIVPELYLPEVKPKVVALPLRPAIKRELVLVVRNLQSVSPITAEFIVHSQRYVSAA
>NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein
MFKLLSVGNPLGLDQSVTVGIISGKDRPLHIGDRFFGNVVQTDAAINPGNSGGPLINMLGEVIAVNTLMAYPSQGISFAISIDEIKPLIRRYQ
>NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein
MVLKPHVAINVKELDASIEFYRHLFGEEPAKVRPGYGKFDLDEPALNFTLNEGGEITGGINHLGIQVGSTEAVIAAKERLKNAGLASFDEMDTTCCYARQDKIWVTSPDGHQWEVFFVKEDADSFGQSPAIPEADSPCCTPK
>NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator
MACCTSEQLSLIARALSDPIRYQILDLIARGNSEDAAVCCTAEMCVCDIQEVLDLKQSKVSYHLKELKNAGLLHERKQGKWNYYSVNQSMLKAFCDELSRRFHLPDEGVTP
>NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein
MTSYILPVLKKSILMTFRIYLSIVFLIYGLAKFWPGQFPNGTHVVYDSSVNSPFDLAWAFFGHSRMYELMIGAGEVTAAILLLIPRTRTLGALIYFPIALNVMMVNYFFEIGVLDLSTVMVVMAGCLLLADFKKISVLWSPDLQERGRNKE
>NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MESHPFKTKEGPVILFDGVCNLCNSWVQFVIRRDSQVRFRFASLQSPVGSSLRTSCGIPQNSDSIVLVEEQRCFHQSSAVLRICKGLDGFWKWLYIFILIPKPLRDWVYRWVARNRYRFFGKRDACMIPTKNMRSRFLDEG
>NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter
MRFSTLLTLTLSIFTVGIVELIIAGILELVAQDLQVSPSLAGQLITLYAFTFAIASPVLMTLTANVERRLLLILSLIVFILTNLATAFSSSWMAISVARVATAMSAAVYVVTALGVTAKLADESFRGRALGYVYMGFSAANIFGVPLGTAIGVWFGWRNTFIMIAGLGFLSLFGIWKTIPSLEGQKSSSLGEALKVAGNPRILGMLGVTSFLLAGHYMVYAYISPFLTTAGYSLTAVSLFLLLAGIVGTLGTSLGGIMTDRIGAVPSLRIAVFLFIGSLGLLPFSLDIMWITLILFAIWNLSIWSINSPSQYCLIQLSPQSSDLALSLNMSALNIGIGLGSAMGGLLLLKFPVIYSAWAGCALGVIGLLCFSFAKKALPASS
>NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
METLLQHCQDQGKSIGEVMLDYEVKKSGRSREKVLEMMVERLKKMKEAVDQGSDDPSPAPSGISGGDAKIMGQYRKEDHPFSGPLIFDAMRFAFATSEHNARMGVIVATPTAGSAGVLPGCLFSLYDNAGYSFDSLVMGLMTASAIGFVIANRSFVSGAAGGCQAEVGSAVAMAAAAIVELKGGKPAQAIHAAAISLKSMLGLVCDPVAGLVEVPCIKRNAIGTAIAFSAADIAMAGVESRIPCDEVIATMYDIGRSMPRTLRETSLGGLAVTPTGKKVKERLFQQNKDEARRKTESQPCRESNVD
>NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein
MNYQSCFDIIGPIMVGPSSSHTAGVVSIGKFVHDYMGGPPERSEIVFYDSFAETYQGHGTDKAIVGGLLGMKTDDIGIRHALEEASRRNVIINFCLEGSCPHYDHPNTVMTWNERNGEIFSIGGVSLGGGVSKIFLIDGLKVDLPLNEPVDMDELRNKARKKLSKDAAVAVKEG
>NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase
MSLSVHDPDLFQAIESERKRQHQTLELIASENFVSQDVLEAMGTELTNKYAEGYPGKRYYGGCEFVDVVENLAIERLKKLFGAGFANVQPHSGSQANTAVYFSLLQPGDTIMGMNLSHGGHLTHGSPVSISGKWFHVVDYGVKEDTHRIDYDQVEAIAKRERPKLIIAGTSAYPRQIDFSKFRDIADQVGAYLMVDMAHIAGLVAAGIHPSPIPHADVVTSTTHKTLRGPRGGVILTNDEDLAKKMNKAVFPGTQGGPLMHIIAAKAVAFKEALSPEFKEYAHQVVKNAQTLAETLKQEGATLVSGGTDNHLLLLDVRPWELTGKEAEKWLEDAGITVNKNTIPYDPASPFVTSGIRIGTAAVTSRGMGTKEMKHIGELIATVLKSKGEPEILRQVRTSVRELCEHSPLHVSAVGG
>NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein
MAKATTNIVHLKPGEQEEPTQTVEDLLRILAEHRESVEKSVKLLEQLHQKGLLDLAIAGLEQGDHVLDVLVKQASRPATVNGIQTVIALAQLSLALDPQKVSQLGKGVISGMEAAATNKGPQIDGMLDLLKALRDPDVARGLSAMMAILKGLGSSLSTSPGEEKQ
>NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha
MSEETQIKVRLDGKEVRIKPGTTVLQTILEERDFPHVCYHPALGPIETCDTCITEVDGKLVRACSTEARQGMEILTFSEASRKARKEGMDRLLHNHELYCTVCDNNNGNCVVHNTAMMMEVEHQKYPFSPKPYPEDNSNPFYRYDPDQCILCGRCVEACQNLQVSEVLSIDWKRERPRVIWDQDVPINESSCVSCGHCVTVCPCNALMEKSMLGEAGFLTGIPTPTLESMIDLTKEVEPGYSSIFAISEMEEKLRESRIKKTKTVCTYCGVGCSFDVWTKDRKILKVEPQMEAPANQISTCIKGKFGWDFVNSSERLVKPLIRKGDTFYPAEWDEALNYVAKRLSSIREEHGPDAIGCISSSKCTNEENYLMQKFARSVIGTNNIDNCSRYCQSPATFAMRQTMGYGGDSGSITDIAATDLVIIIGANPAESHPVLSTRVRRAQKKNGQKLIVADLRKNGMAERADVWLHPKPGSDLIWISAVTKYLIDQGWYDQTFVKERVRGFTDYRNSLERYTLEYAEEVSGIKREQLIQTAEMIRDADRMCLLWAMGVTQHMGGSDTSTAICNLALVTGQVGRPGTGVYPLRGHNNVQGAGDFGCAPDVLPGYESVWDEEVRAKYEQAWNVKLPTTHGSDNHLMVEKIHKGELKALYLKGEEMALVDSNANHVTGAFEKLEFFVVQDVFFSKTAQYADVIFPASPSLEKEGTFTNTERRIQRLYQVLEPLGDSKPDWQIITELANRMGAGWSYEHPREILHEAVSLATLMKGVTYERLEGYHSLQWPVAPDGTDTPLLYTDGFPFDDGKARLVPVEWTHPLELADEYDLHLNNGRILEHFHEGNLTYRVEGIQEKVPTAYVEVSRDLAKERELESGRMVRLVSPYGAVKVPVVVTDRVKGKELYLPMHTTNAEEAVNFLTSSYHDRQTHTPAYKEMSVRMEVLGEKKDSPMKRGNYRLGHPNPQPGVQVEEKWKRDDYEPLVSED
>NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein
MVTIGNLIKSRASLTPDLEAVVCENRRIGYRDYNIMINQLADYLLERNIQKGDRIALLCHNHSSFPLIYLAAAKIGAITVPLNWRAKPDEIRWMLEDCEPKILFYDDLFRPFLSSLEDLSFLETTIPVGDSEETNRFFENLFLHRRDQEPDRTVRSHDPALIIYTSGTTGKPKGVVCTHQNVYTAGLGNVNTLDLWMGDRFLFVTPLFHISGMMFIINAIIRGFTLVLNPRFDPVHIWDLIEQEKITGMMSVPSMLSFMLETVKTRNQVASSLRSILSGGSLVPEKLIRDFYELGYPVSQVYGATEYTGAITYWMPHMDIQRCDSVGKGLYLTEIKVIDPISGNGLPPGEIGEILCRGPQIFAGYWNRKEESDQVLKNGWYHTRDVGKLDSDGYLYVIDRLRDMIIVSGEKVFPAQVEAIINQLEEVEEVAVVGVQHDVWGELSKAYVVKKDTASSLSESEIIQHTRRQLADYNLHEVEFVKELPKNGMGKVLKYLLREYANQSAS
>NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein
MDPLEINEMGELIRKRRKERKLRLEDLADEHISPATISNIERGVPHVNPDKIQYLMDKLDLDMDNISKLIVNEQKQLQKLRFQLTAIETMQDMGHSREAVRRLDELDLEDNHPFSPIYYLIKGRHYLDSGRYRRAERSFFNVIRLSNLTPHGQKSNLEATGYYELGRVNHAQNLLSQALQYVDNGLQAFKPDGDHGEIRFKLYQSKALYLETMNRVGEAIQVVDHVWKDLSQTRDLDTLLRFYRIRTDLLCRIGMTEEAMEIAKEGLEIARHNCINQRTFELWCSLGSVYLTKTAWDEAELCYNLALKLRGKIEDESAIILIFTRLGILYMNQGKWEQGEKMLSEAIALGDRLAHYPLLIEALMATGTFYHQRGESQYGLPYFEKAFQLSKRYGTIKKQYMALFHLAQCCEKLDRQKFAWCMRELYEVQRNMKDVDLNSLETII

Crispr_ID: NZ_CP048104_9

• CRISPR_ID: NZ_CP048104_9
• CRISPR_location: 2737671-2738070
• CRISPR_type: TypeI-A
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas6,csa3

Consensus repeat of NZ_CP048104_9

Consensus_repeat	Method
GTTTCAATCCTCTAACCGAGGTGCTTTATATTGTGAC	PILER-CR
GTTTCAATCCTCTAACCGAGGTG	CRISPRCasFinder
GTTTCAATCCTCTAACCGAGGTGCTTT	CRT

spacers of NZ_CP048104_9

>9.1|2737708|35|NZ_CP048104|PILER-CR
ATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
>9.2|2737780|35|NZ_CP048104|PILER-CR
AGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
>9.3|2737852|38|NZ_CP048104|PILER-CR
TACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAA
>9.4|2737927|34|NZ_CP048104|PILER-CR
CACAGGAAACATTAAAGAACCGTTGAATCTTCCG
>9.5|2737998|39|NZ_CP048104|PILER-CR
AAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCT
>9.6|2737694|49|NZ_CP048104|CRISPRCasFinder
CTTTGTATTGTGACATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
>9.7|2737766|49|NZ_CP048104|CRISPRCasFinder
CTTTGTATTGTGACAGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
>9.8|2737838|49|NZ_CP048104|CRISPRCasFinder
TTGTGTATTGTTACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAA
>9.9|2737910|48|NZ_CP048104|CRISPRCasFinder
CTTTATATTGTGACCACAGGAAACATTAAAGAACCGTTGAATCTTCCG
>9.10|2737981|53|NZ_CP048104|CRISPRCasFinder
CTTTATATTGTGACAAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCT
>9.11|2737698|45|NZ_CP048104|CRT
GTATTGTGACATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
>9.12|2737770|45|NZ_CP048104|CRT
GTATTGTGACAGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
>9.13|2737842|45|NZ_CP048104|CRT
GTATTGTTACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAA
>9.14|2737914|44|NZ_CP048104|CRT
ATATTGTGACCACAGGAAACATTAAAGAACCGTTGAATCTTCCG
>9.15|2737985|49|NZ_CP048104|CRT
ATATTGTGACAAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCT

CRISPR arrays and Neighbor proteins around NZ_CP048104_9

CRISPR arrays

The CRISPR arrays of NZ_CP048104_9

>merge|NZ_CP048104|9|2737671-2738070|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACATGCGGGGAATTGAACGGAGGTCGGTTTATGAACTGTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGACAGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAGGTTTCAATCCTCTAACCGAGGTGTTGTGTATTGTTACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAAGTTTCAATCCTCTAACCGAGGTGCTTTATATTGTGACCACAGGAAACATTAAAGAACCGTTGAATCTTCCGGTTTCAATCCTCTAACCGAGGTGCTTTATATTGTGACAAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCTGTTTCAATCCTCTAACCGAGGTGCTTTATATTGTGAC

>NZ_CP048104|9|8|2737671-2738070|PILER-CR
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGAC	ATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
GTTTCAATCCTCTAACCGAGGTGCTTTGTATTGTGAC	AGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
GTTTCAATCCTCTAACCGAGGTGTTGTGTATTGTTAC	TGGGGAACGGATCGTGGCCCGTTCCCCACCATTAAGTT
TCAATCCTCTAACCGAGGTGCTTTATATTGTGACCAC	AGGAAACATTAAAGAACCGTTGAATCTTCCGGTT
TCAATCCTCTAACCGAGGTGCTTTATATTGTGACAAA	AGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCTGTT
TCAATCCTCTAACCGAGGTGCTTTATATTGTGAC

>NZ_CP048104|9|8|2737671-2738057|CRISPRCasFinder
GTTTCAATCCTCTAACCGAGGTG	CTTTGTATTGTGACATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
GTTTCAATCCTCTAACCGAGGTG	CTTTGTATTGTGACAGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
GTTTCAATCCTCTAACCGAGGTG	TTGTGTATTGTTACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAA
GTTTCAATCCTCTAACCGAGGTG	CTTTATATTGTGACCACAGGAAACATTAAAGAACCGTTGAATCTTCCG
GTTTCAATCCTCTAACCGAGGTG	CTTTATATTGTGACAAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCT
GTTTCAATCCTCTAACCGAGGTGC

>NZ_CP048104|9|6|2737671-2738060|CRT
GTTTCAATCCTCTAACCGAGGTGCTTT	GTATTGTGACATGCGGGGAATTGAACGGAGGTCGGTTTATGAACT
GTTTCAATCCTCTAACCGAGGTGCTTT	GTATTGTGACAGAGGGCAGCCCTGCCGGACAGAGCAGTGAATAAG
GTTTCAATCCTCTAACCGAGGTGTTGT	GTATTGTTACTGGGGAACGGATCGTGGCCCGTTCCCCACCATTAA
GTTTCAATCCTCTAACCGAGGTGCTTT	ATATTGTGACCACAGGAAACATTAAAGAACCGTTGAATCTTCCG
GTTTCAATCCTCTAACCGAGGTGCTTT	ATATTGTGACAAAAGGCCGGGTGTTATTTCTCGGCCTTTGGCAACTTCT
GTTTCAATCCTCTAACCGAGGTGCTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl|CDD|225918
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	unknown	unknown	gnl|CDD|129802
NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	unknown	unknown	gnl|CDD|225283
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	unknown	unknown	gnl|CDD|223232
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl|CDD|225556
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341286
NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|238045
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl|CDD|187783
NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl|CDD|129801
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	unknown	unknown	gnl|CDD|225371
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	unknown	unknown	gnl|CDD|319917
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	6e-19	63.9	0.0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	2.7e-20	67.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha	gnl|CDD|225918	COG3383, COG3383, Uncharacterized anaerobic dehydrogenase [General function prediction only].	0
NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.05921e-19
NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.08868e-48
NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein	gnl|CDD|225283	COG2427, COG2427, Uncharacterized conserved protein [Function unknown].	1.39757e-16
NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase	gnl|CDD|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	1.32815e-95
NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl|CDD|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.49129e-42
NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein	gnl|CDD|341286	cd17631, FACL_FadD13-like, fatty acyl-CoA synthetase, including FadD13. This family contains fatty acyl-CoA synthetases, including Mycobacterium tuberculosis acid-induced operon MymA encoding the fatty acyl-CoA synthetase FadD13 which is essential for virulence and intracellular growth of the pathogen. The fatty acyl-CoA synthetase activates lipids before entering into the metabolic pathways and is also involved in transmembrane lipid transport. However, unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length of C26, and this is facilitated by an extensive hydrophobic tunnel from the active site to a positively charged patch. Also included is feruloyl-CoA synthetase (Fcs) in Rhodococcus strains where it is involved in biotechnological vanillin production from eugenol and ferulic acid via a non-beta-oxidative pathway.	8.53596e-156
NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.61576e-08
NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl|CDD|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	5.70099e-08
NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl|CDD|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	6.24798e-96
NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	9.36644e-73
NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	5.11079e-51
NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein	gnl|CDD|319917	cd07254, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.24507e-49
NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	1.71831e-29
NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein	gnl|CDD|129802	TIGR00719, Probable_L-serine_dehydratase_beta_chain, L-serine dehydratase, iron-sulfur-dependent, beta subunit. This enzyme is also called serine deaminase. This model describes the beta chain of an iron-sulfur-dependent L-serine dehydratase, as in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of beta chains from the homologous region of single chain forms such as found in E. coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.75676e-41

Protein sequences

>NZ_CP048104.1|WP_173223818.1|2737322_2737472_-|hypothetical-protein
MMIEEEWMVRVVIKGSPFYPFDKDESLEEGGFYTGEWCFRLEKEQHSIL
>NZ_CP048104.1|WP_173223816.1|2735307_2736099_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYQLCLSVKPRSKVKNRWVLSRRLHGFILRMIKMQDPQLSEWLHNRKDRQFFSCHSSFQEKEWYIQTPSREIVRCLQQSLLSHPVIDLRDWTGEIQEIHCYSYTVKDMLQNFSPKVTFQFHTPTTFYQWGNYYPMPELQRLFASGAKSYEMDGNIPIPWEEIEPLTRRVRIEHLSITTQRADFGKFKVVGFCGTLAFSLKALSAEEQKKMWLLANYGSLMGFGYKTAWGLGQTSIREQLRTPPASESTQGVFGKQEPLEIQGI
>NZ_CP048104.1|WP_173225669.1|2733368_2734784_-|amidase
MNVWDLDACGVLEAMGSGKVTSAQAVQGYRDQIERTNPTLNYLVEDRFAKALQEAKECDRRQQEGTGKLWGVPISIKEAYNVAGMKTTGGLFHRKDQVEESDAAVTAKLKAAGAVILGKTNTPTLCFCQESENKLYGRTNNPWNPERTAGGSSSGEGAIIAVGGAAAGIGSDIGGSIRFPSHFNGVVGFKSGHGQVDQQGHFPFVDHPLQERMLGLGPMTKSVRDTRLIYNIIAKTPAPKKEVADYVITFLPQTTYPLSKVTVTLMHQVKAFFNKELETEEAVPPWFDPSALMWQEIMSVDGGEGTAKIAFGDRAARPVWEYLKEITTGKSEWHRHLTWALIGARLFRPGAKRVREIEEILHQGDEELDRYLDKRILVFPVYHCGAPIHGDLYREIFSIRKTFLRYMPYVAYANVWGLPSLTIPVGTDGDGMPISLQLMSRNRNEEALFQLGEIVEKQFRGYLRCDHGEDQ
>NZ_CP048104.1|WP_173223814.1|2732781_2733024_-|hypothetical-protein
MSQGLKVTDIGKYQRLRETEDLLRRASHGYKPERGTESLQLWHTTNPAGVLTTPSKESEADMSAEVLKAIQDLNKQLAEV
>NZ_CP048104.1|WP_173225666.1|2732481_2732775_-|hypothetical-protein
MNNKIDHTQNELRNEISTVKSDLKEDVSAIKDNVDHISETVTQLDKTTGILEERTKDIATQAHVSSEIHSTHLKILVWIVGTALTVGAMTVSIVKLL
>NZ_CP048104.1|WP_173223812.1|2731450_2732251_+|SagB/ThcOx-family-dehydrogenase
MHPDWQRICNEFLEATSYSLGELEKGWASNYDFSKRPPTYLRYEESLARIPLGTPDFPSSPDLWQLLRERRSKRNFTKTPLTLNELNLLLWGTTGITADMGDYQLRTVPSAGALYPIETYLLVNNVESLDQGLYHLDVENWCLELLKREDVSEVAHLYTEEQEMTRHAAVNFVWTAMVDRTKDKYKERAYRYVWWDAGHVAQNLHITGNALGLGVCTIGHWFDKNMNDYLGIDGISHFSVLMASAGKVTGGHWLEDRRPVVSDSGE
>NZ_CP048104.1|WP_173223810.1|2730461_2731322_-|LysR-family-transcriptional-regulator
MTLAQLQVFITAAESGSFTRAADSLGYTQSAVSQMVNSLEKELGVQLFHRSRSGIATTGIGERMLSHARHILQITSCMQQEAASAQGLEEGVLRIGSIPSVAAKVLPSLIGSFRRRFPQVDIVLFEGEHEEIHNWITSSVVDVGFTSMPDKELHTIPLLWDEMRVILPDQHSLKDEPFLTFSQIRDRCFIMPKDHSIKQLLRANGITPDVTFEVRDVTTILAMVQEWIGVTIVPELYLPEVKPKVVALPLRPAIKRELVLVVRNLQSVSPITAEFIVHSQRYVSAA
>NZ_CP048104.1|WP_173223808.1|2729900_2730182_+|trypsin-like-peptidase-domain-containing-protein
MFKLLSVGNPLGLDQSVTVGIISGKDRPLHIGDRFFGNVVQTDAAINPGNSGGPLINMLGEVIAVNTLMAYPSQGISFAISIDEIKPLIRRYQ
>NZ_CP048104.1|WP_173223806.1|2729186_2729615_-|VOC-family-protein
MVLKPHVAINVKELDASIEFYRHLFGEEPAKVRPGYGKFDLDEPALNFTLNEGGEITGGINHLGIQVGSTEAVIAAKERLKNAGLASFDEMDTTCCYARQDKIWVTSPDGHQWEVFFVKEDADSFGQSPAIPEADSPCCTPK
>NZ_CP048104.1|WP_173223804.1|2728776_2729112_-|winged-helix-turn-helix-transcriptional-regulator
MACCTSEQLSLIARALSDPIRYQILDLIARGNSEDAAVCCTAEMCVCDIQEVLDLKQSKVSYHLKELKNAGLLHERKQGKWNYYSVNQSMLKAFCDELSRRFHLPDEGVTP
>NZ_CP048104.1|WP_173223820.1|2739172_2739628_-|hypothetical-protein
MTSYILPVLKKSILMTFRIYLSIVFLIYGLAKFWPGQFPNGTHVVYDSSVNSPFDLAWAFFGHSRMYELMIGAGEVTAAILLLIPRTRTLGALIYFPIALNVMMVNYFFEIGVLDLSTVMVVMAGCLLLADFKKISVLWSPDLQERGRNKE
>NZ_CP048104.1|WP_173223822.1|2739641_2740067_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MESHPFKTKEGPVILFDGVCNLCNSWVQFVIRRDSQVRFRFASLQSPVGSSLRTSCGIPQNSDSIVLVEEQRCFHQSSAVLRICKGLDGFWKWLYIFILIPKPLRDWVYRWVARNRYRFFGKRDACMIPTKNMRSRFLDEG
>NZ_CP048104.1|WP_173223824.1|2740410_2741559_+|MFS-transporter
MRFSTLLTLTLSIFTVGIVELIIAGILELVAQDLQVSPSLAGQLITLYAFTFAIASPVLMTLTANVERRLLLILSLIVFILTNLATAFSSSWMAISVARVATAMSAAVYVVTALGVTAKLADESFRGRALGYVYMGFSAANIFGVPLGTAIGVWFGWRNTFIMIAGLGFLSLFGIWKTIPSLEGQKSSSLGEALKVAGNPRILGMLGVTSFLLAGHYMVYAYISPFLTTAGYSLTAVSLFLLLAGIVGTLGTSLGGIMTDRIGAVPSLRIAVFLFIGSLGLLPFSLDIMWITLILFAIWNLSIWSINSPSQYCLIQLSPQSSDLALSLNMSALNIGIGLGSAMGGLLLLKFPVIYSAWAGCALGVIGLLCFSFAKKALPASS
>NZ_CP048104.1|WP_173225672.1|2741729_2742650_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
METLLQHCQDQGKSIGEVMLDYEVKKSGRSREKVLEMMVERLKKMKEAVDQGSDDPSPAPSGISGGDAKIMGQYRKEDHPFSGPLIFDAMRFAFATSEHNARMGVIVATPTAGSAGVLPGCLFSLYDNAGYSFDSLVMGLMTASAIGFVIANRSFVSGAAGGCQAEVGSAVAMAAAAIVELKGGKPAQAIHAAAISLKSMLGLVCDPVAGLVEVPCIKRNAIGTAIAFSAADIAMAGVESRIPCDEVIATMYDIGRSMPRTLRETSLGGLAVTPTGKKVKERLFQQNKDEARRKTESQPCRESNVD
>NZ_CP048104.1|WP_173223826.1|2742666_2743191_-|hypothetical-protein
MNYQSCFDIIGPIMVGPSSSHTAGVVSIGKFVHDYMGGPPERSEIVFYDSFAETYQGHGTDKAIVGGLLGMKTDDIGIRHALEEASRRNVIINFCLEGSCPHYDHPNTVMTWNERNGEIFSIGGVSLGGGVSKIFLIDGLKVDLPLNEPVDMDELRNKARKKLSKDAAVAVKEG
>NZ_CP048104.1|WP_173223828.1|2743205_2744456_-|serine-hydroxymethyltransferase
MSLSVHDPDLFQAIESERKRQHQTLELIASENFVSQDVLEAMGTELTNKYAEGYPGKRYYGGCEFVDVVENLAIERLKKLFGAGFANVQPHSGSQANTAVYFSLLQPGDTIMGMNLSHGGHLTHGSPVSISGKWFHVVDYGVKEDTHRIDYDQVEAIAKRERPKLIIAGTSAYPRQIDFSKFRDIADQVGAYLMVDMAHIAGLVAAGIHPSPIPHADVVTSTTHKTLRGPRGGVILTNDEDLAKKMNKAVFPGTQGGPLMHIIAAKAVAFKEALSPEFKEYAHQVVKNAQTLAETLKQEGATLVSGGTDNHLLLLDVRPWELTGKEAEKWLEDAGITVNKNTIPYDPASPFVTSGIRIGTAAVTSRGMGTKEMKHIGELIATVLKSKGEPEILRQVRTSVRELCEHSPLHVSAVGG
>NZ_CP048104.1|WP_173223830.1|2744942_2745440_-|DUF1641-domain-containing-protein
MAKATTNIVHLKPGEQEEPTQTVEDLLRILAEHRESVEKSVKLLEQLHQKGLLDLAIAGLEQGDHVLDVLVKQASRPATVNGIQTVIALAQLSLALDPQKVSQLGKGVISGMEAAATNKGPQIDGMLDLLKALRDPDVARGLSAMMAILKGLGSSLSTSPGEEKQ
>NZ_CP048104.1|WP_173223831.1|2745718_2748658_-|formate-dehydrogenase-subunit-alpha
MSEETQIKVRLDGKEVRIKPGTTVLQTILEERDFPHVCYHPALGPIETCDTCITEVDGKLVRACSTEARQGMEILTFSEASRKARKEGMDRLLHNHELYCTVCDNNNGNCVVHNTAMMMEVEHQKYPFSPKPYPEDNSNPFYRYDPDQCILCGRCVEACQNLQVSEVLSIDWKRERPRVIWDQDVPINESSCVSCGHCVTVCPCNALMEKSMLGEAGFLTGIPTPTLESMIDLTKEVEPGYSSIFAISEMEEKLRESRIKKTKTVCTYCGVGCSFDVWTKDRKILKVEPQMEAPANQISTCIKGKFGWDFVNSSERLVKPLIRKGDTFYPAEWDEALNYVAKRLSSIREEHGPDAIGCISSSKCTNEENYLMQKFARSVIGTNNIDNCSRYCQSPATFAMRQTMGYGGDSGSITDIAATDLVIIIGANPAESHPVLSTRVRRAQKKNGQKLIVADLRKNGMAERADVWLHPKPGSDLIWISAVTKYLIDQGWYDQTFVKERVRGFTDYRNSLERYTLEYAEEVSGIKREQLIQTAEMIRDADRMCLLWAMGVTQHMGGSDTSTAICNLALVTGQVGRPGTGVYPLRGHNNVQGAGDFGCAPDVLPGYESVWDEEVRAKYEQAWNVKLPTTHGSDNHLMVEKIHKGELKALYLKGEEMALVDSNANHVTGAFEKLEFFVVQDVFFSKTAQYADVIFPASPSLEKEGTFTNTERRIQRLYQVLEPLGDSKPDWQIITELANRMGAGWSYEHPREILHEAVSLATLMKGVTYERLEGYHSLQWPVAPDGTDTPLLYTDGFPFDDGKARLVPVEWTHPLELADEYDLHLNNGRILEHFHEGNLTYRVEGIQEKVPTAYVEVSRDLAKERELESGRMVRLVSPYGAVKVPVVVTDRVKGKELYLPMHTTNAEEAVNFLTSSYHDRQTHTPAYKEMSVRMEVLGEKKDSPMKRGNYRLGHPNPQPGVQVEEKWKRDDYEPLVSED
>NZ_CP048104.1|WP_173223833.1|2749666_2751187_+|AMP-binding-protein
MVTIGNLIKSRASLTPDLEAVVCENRRIGYRDYNIMINQLADYLLERNIQKGDRIALLCHNHSSFPLIYLAAAKIGAITVPLNWRAKPDEIRWMLEDCEPKILFYDDLFRPFLSSLEDLSFLETTIPVGDSEETNRFFENLFLHRRDQEPDRTVRSHDPALIIYTSGTTGKPKGVVCTHQNVYTAGLGNVNTLDLWMGDRFLFVTPLFHISGMMFIINAIIRGFTLVLNPRFDPVHIWDLIEQEKITGMMSVPSMLSFMLETVKTRNQVASSLRSILSGGSLVPEKLIRDFYELGYPVSQVYGATEYTGAITYWMPHMDIQRCDSVGKGLYLTEIKVIDPISGNGLPPGEIGEILCRGPQIFAGYWNRKEESDQVLKNGWYHTRDVGKLDSDGYLYVIDRLRDMIIVSGEKVFPAQVEAIINQLEEVEEVAVVGVQHDVWGELSKAYVVKKDTASSLSESEIIQHTRRQLADYNLHEVEFVKELPKNGMGKVLKYLLREYANQSAS
>NZ_CP048104.1|WP_173223835.1|2751625_2752960_+|tetratricopeptide-repeat-protein
MDPLEINEMGELIRKRRKERKLRLEDLADEHISPATISNIERGVPHVNPDKIQYLMDKLDLDMDNISKLIVNEQKQLQKLRFQLTAIETMQDMGHSREAVRRLDELDLEDNHPFSPIYYLIKGRHYLDSGRYRRAERSFFNVIRLSNLTPHGQKSNLEATGYYELGRVNHAQNLLSQALQYVDNGLQAFKPDGDHGEIRFKLYQSKALYLETMNRVGEAIQVVDHVWKDLSQTRDLDTLLRFYRIRTDLLCRIGMTEEAMEIAKEGLEIARHNCINQRTFELWCSLGSVYLTKTAWDEAELCYNLALKLRGKIEDESAIILIFTRLGILYMNQGKWEQGEKMLSEAIALGDRLAHYPLLIEALMATGTFYHQRGESQYGLPYFEKAFQLSKRYGTIKKQYMALFHLAQCCEKLDRQKFAWCMRELYEVQRNMKDVDLNSLETII

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP048104_5	5.2|1698883|37|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT	1698883-1698919	37	KX507046	Vibrio phage S4-7, complete genome	35559-35595	9	0.757

1. spacer 5.2|1698883|37|NZ_CP048104|PILER-CR,CRISPRCasFinder,CRT matches to KX507046 (Vibrio phage S4-7, complete genome) position: , mismatch: 9, identity: 0.757

gttggtctgcggtgaaatgttccatcatctcagctat	CRISPR spacer
cctcttgtgcggtggagtgttccatcatctcagcaaa	Protospacer
 .*  * *******.*.***************** * 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	531878 : 541853	9	Synechococcus_phage(37.5%)	NA	NA
DBSCAN-SWA_2	867754 : 880104	10	Planktothrix_phage(16.67%)	NA	NA
DBSCAN-SWA_3	1493723 : 1506572	14	Staphylococcus_phage(40.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP048104|531878:541853|DBSCAN-SWA
CATGATTGAACGTTATACCCGACGGGAAATGGGGCGGATTTGGTCAGACGAAAATCGGTACCAGGCATGGTTGGAAGTAGAGATACTGGCTTGTGAGGCTTGGTCTGAGTTGGGTGTCATTCCTCAGGGGGATGTTGCTCAAATTCGTAAAAATGCTGAAGTTGACGTGAAGCGTATTTTGGAAATTGAAGAACAAACCCGACATGATGTGGTGGCTTTTACCCGAGCAGTGGCGGAAACACTGGGTCCGGAATCCAAGTGGGTGCATTATGGACTCACTTCCACGGATGTGGTGGATACAGCACAGTCTTATCTGTTGAAGCAAGCCAATGAAATCCTGTTAAAAGATGTGGATCGCTTTTTGGATGTTTTAAAGAAAAAGGCATTGGCTCATAAAGATACCGTTATGATGGGGCGTACACACGGTGTGCATGCGGAACCTACAACTTTCGGGCTGAAGTTGGCCCTTTGGTACACGGAAATGAAACGAAATCGGGAGCGGTTGGTTCAGGCTGCCGAAAATGTAGCTGTGGGTAAAATATCCGGAGCTGTAGGGACCTATGCCAATATTGATCCCTTTGTGGAAGAGTATGTATGTCGAAAACTGGGATTGACACCGGCGCCTGTTTCAACCCAAACCCTGCAACGGGACCGTCACGCCGATTATTTGTCTACTCTGGCATTGATTGCCGCTTCCTTGGAAAAGTTTGCGGTGGAAATCCGGGGATTGCAAAAAAGCGAAACCAGGGAAGTGGAGGAGGCCTTCGGCAAGGGACAAAAAGGATCCTCCGCGATGCCACATAAACGAAATCCGATCGGTTCCGAAAATATTACGGGTTTGTCCCGAGTGATCCGGGGTCATATGGTTACAGCCTATGAAAATGTGGCTTTATGGCACGAACGGGATATTTCCCATTCCTCTGCAGAACGGGTTATTCTCCCGGACTCCACTATTTTGCTTAACTATATGTTGAATCGCTTTGCCGGGATCGTAGAAAACCTGACTGTTTTTCCGGAAAACATGAAACGAAACATGGATCGGACTTATGGATTGATCTACTCCCAACGTGTTTTATTAACCTTGATCCAGAAAGGCCTGAAAAGGGAGAGGGCCTATGATCAGGTACAAAAGTTGGCCATGCAAGCATGGGAAGAAGCATGTTCTTTCCGTGAGCTGGTGGAGAGGGATAAAACGATCATGGAATATCTGACACCGGAAGAGGTGGAGGATTGCTTTGATTATCGATTCCATCTGAAACGGGTGGACGAAATTTTTAGTCGGGCGGGTCTTCTGTAAAAGGCATCATCACATGTTCCGGATGGAAACAAAGATCGTGTTTCGCTGCATGAATGCTCCTCCAGCCATTTCTTCTGCACACAGGTGGTTATAACGCACTGTTTCGATGGGAACCCTGCCTGATTCAGTTGTCAAGCAATTGCCAGATGGGTGAGGGCGAGGAAAGGAAGAGAAAAGGAAATGAACAAGGGCGAGATGCTGTATGAAGGAAAGGCAAAGAAAGTGTATCTCACTGAAGATCCGGCTCAAGCATGGGTGGAGTACAAGGATGATGCTACTGCTTTTAATGCCAGGAAGAAAGGGGCCATCACTGGTAAAGGGGAATTGAACAATCAAATCAGCGCCTTTTTCTTCCGGTTTTTAGGGGAACAAGGCATTCCTCATCACTTTATTCAGACCTTGTCCAACCGGGAGCAACTGGTGAAAAAGGTAGCCATACTTCCAGTGGAGGTGGTGGTACGCAACCGGGTGGCGGGATCTCTGGCGAAGCGGCTGGGTTTGGAAGAGGGGATGACCTTGTCCGTCCCGATCGTCGAATTTTACTATAAAAGTGATGAGTTGGATGATCCCCTGATTACTGAAGATCATATCCGTTTGTTACAGCTGGCCACGACAGACCAAGTGAATCAGATGCGAAAAATGGCTTTGGATGTCAACGGGCATTTACAAAAACTGATGGCTGCAAAAGGCATTCAACTGGTGGATTTTAAGTTGGAATTTGGTTTGGACAATGAACAACGGCTCCTGCTGGCGGATGAAATCTCCCCGGATACTTGCCGGTTTTGGGATACTGCGACAGGAAAAAAGCTGGATAAGGACCGATTCCGACGGGATTTGGGAGATGTCGAAGGTGCTTATCGCGAAATTTGGAACCGCTTGGGAGGAGAAGCACATGATTAAAGCAACCATTGTCATTCGATTGAAATCCAGTGTAGTGGATCCCCAGGGTCATGCTGTCAAAGGCTCTCTTCATTCTCTGGGTTTTGAAGAAGTCCAGGATGTTCGCATCGGCAAAATGATAGAGGTTTGGTTGGAGAGTGCTGATTTAGAGGCGGCGAAAGTAAAGGTGGAGGCCATGTGCAAACAGCTGTTGGCCAATCCGGTCATTGAAAATTACGAATACCAGTTGGAGGAGGAAGCCTGAATGCGCTTTGCTGTTCCTGTTTTCCCCGGTTCCAGTTGTGATATGGACTGTATCAAAGCAGTGAAAGAAATCCTGAATCACCCGGCAGATCCCGTTTGGCACAATGACAGAAACTTGGATTCCTATGATGCGATTATCCTGCCAGGAGGTTTCTCCTATGGGGACTATCTCCGTGCCGGTGCCTTGGCCCAATGTTCTCCTGTGATGGAAGGAGTGCGGAAAGCAGTGGATCAAGGCAAGCTGGTTATCGGAATCGGCAATGGATTTCAGCTTTTATTGGAGGCGGGTTTGCTGCCGGGGGCCATCCGGGTCAATGACCACCTTCAATTCCGGTGTGCCATGCAAGGACTCAAAGTGGAAAACAATACTCTTCCCTTTACCCTGGATTACCATGCACAGGAGGAAATTGTACTTCCCATTGCCCATGGTGAAGGCAATTACTACTGTGACGATAAAACTCTTCACCAACTGGAGGAATCCGGCCGGATTGTGTTTCGGTATATAAAAGGCAATCCAAACGGTTCTGTAGGGGATATTGCCGGGATTGTGAATGAACAGGGAAATGTGTTGGGGATGATGCCTCATCCGGAACGGGCGATCCGTGAGTGGATGGGTTCCAAAGACGGGGTTCGATTATTTACTTCAATGCTTCATTACTGGGGGGAAAAACACGGTGCAGCCTAAACAGACTCCATGTACAGGGACATCAAAGGAACCGACTTCTGAAGAAATACGGGAACAACATCTGTATCAGGATCTGGGGATGACGACAGAGGAATTTGAGCAGGTTCAGCAACATTTGGGGCGGTTGCCCAATTGGACGGAGTTGGGGATTTACAGTGTGATGTGGTCGGAACATTGCAGTTATAAAAACTCCAAACCTTTGTTGCGACGTTTTCCAGTGTCAGGGTCCAAGGTTCTGCAGGGACCGGGTGAAGGGGCTGGAGCCATTGATATCGGAGAAGGTCAGGCTGTCGTGTTTAAAATTGAAAGTCATAATCATCCTACGGCGGTGGAACCTTTCCAGGGAGCCGCTACCGGTGTGGGAGGGATCATCCGGGATGTGTTTTCCATGGGGGCCCGACCTGTCGCTTTGTTGAACTCCCTTCGTTTTGGCTCCCTGGACTCTGATCGGGCTCGGTATCTCTTTGGCCGGGCGGTTGCCGGAATCGCTCATTATGGTAATAGAATGGGAGTCCCTACGGTGGGAGGAGAAGTGGAGTTCGATGAAGGGTATGACGATAATCCCTTGGTCAATGCCATGTGTGTCGGGATTCTTCCCCACAAGGACTTGCAAAAAGGGATTGCGACAGGAACCGGAAACCCCGTCATCTATGTAGGTGCCAGTACAGGCAGAGACGGGATTCACGGGGCTACTTTCGCTTCAGAGGAGCTGTCTGAGGACTCCGGGGATAAACGTCCATCGGTTCAGGCCGGGGATCCTTTTATGGAGAAGCTGTTGCTGGAGGCATGTTTAGAACTGGTGGAAAAGGAAGTTCTGTTAGGGATCCAGGACATGGGAGCAGCGGGTTTGACCTGTTCCAGTGCCGAGATGGCTGCCAAAGGCGATGCCGGAATGGAGCTGAACCTGGATCACGTTCCCCAGAGAGAAGCGGGTATGACCCCTTATGAAATGATGCTGTCCGAATCCCAGGAACGGATGTTACTCGTTGTGGAAAAAGGACGGGAAGGGGAAGTCCAGGAAGTTCTGGACAAATGGGGATTACAATCCGCTGTTGTGGGCCGGGTTACTGATGATCAACGATACCGAATCCGGTTTCAAGGGGAAATCGTAGCAGATATTCCTGTTAAAACTTTGGTGGATGATGCTCCTGTTCTGACTCGAACCGGATCAGTACCGCAATATTATAAGGATTTCGCCGAAAAGACCTTTGAGCCGGAATTGGCGGAGGTTAACCCTGAGGATGCATTGCAAAAGATGTTGGCTTCACCGAATATCGCCAGTAAAAGATGGGTGTATCAGCAATATGACCATATGGTTGGTACCAGTACCGCAGTCCGACCCGGTTCCGATGCAGCTGTGATCGTCTTGGACGGAACCGATAAGGCCCTGGCGATGTGTACCGATGGCAACAGCCGATATGTTTATTTGGATCCTCGACATGGAGGGGCCATCGCCGTAGCGGAAGCAGCCCGGAATGTGGTCTGCTCCGGGGCTCAACCCTTGGCGATCACGGATTGTCTCAATTTTGGCAGTCCGGAAAAACCCGAGGTTTACTGGCAGTTGGAAGAAGCGATTAACGGAATGTCAGAAGCATGTCGCACCCTGGAGACACCTGTAGTAGGGGGAAATGTCAGCCTGTACAACGAAACCGGGGGTCAACCGATTGCTCCCACACCTGTGGTGGGGATGGTGGGGTTAATTGACAGCCGGGATCATATTACGACACAAGGCTTTAAAAAAGAAGGAGACACGCTTCTGTTATTGGGAGAAACCCAGTTGGAATTAGGCGGGAGTGAATTGCAGCACCAGGTGATTGGAAAAATCTCCGGTCGTCCCCCCAGTGTCAATCTGGAGACGGAAAAACTGTTACACGACTTGGTATTGGAAGCGATTCGAAAAGGATGGGTATCTTCCGCCCATGATCTATCCTCCGGCGGTTTGGCAGTAGCATTGGCGGAGTCGGCAATTTCCGGTTCGATGGGAGCAGAAGTGCAACTGGAACTTTCTTTGGCTCCTTCTCTCTTTCTGTTCAGTGAATCCCAATCCCGCATTCTGCTTTCTGTAGCTTCCCATGAGGCGGAGAATATGCAAGAATTGGCCCGGTTGCGTAATGTTCCCTGTACCAAAATCGGTAAAACCGGAGGTGACCGTTTGCAGGTGAAAATCGGGGGTACTTCCGTCATCCGACTGGCAGTGGAGGAAATGCGCACCATCTGGGAAGGGGCGATACCATGCGCAATGAATCCGACTTCGACGAACTGAAAGAGGAATGTGGGGTATTCGGTATTGTCGGGCACCCTGATGCTGCCGAGTTAGCCTATTATGGTTTGCATGCTTTGCAACACCGGGGGCAGGAGAGTGCGGGAATCGTTGCCACCGATGGAACCGGTTTTCGTTACCATCGAAGTATGGGATTGGTTCATGAGGTGTTTAACCGGGATATCCTGGAAGGGTTGAAAGGGTCCACTGCCATTGGTCACGTCCGATACTCCACTTCCGGGGAAAGTTTGTTGACGAATGCCCAGCCTCTAGTTTTTCACCATGAAAAAGTGGGCCAATTGGCCTTGGCAACCAATGGAAATCTGGTTTATGCCGCAAGGCAGAAAAAAGAGCTGGAAGCACAGGGAGCCGTGTTTCACACCACCTCCGACACAGAGGTAATCGCTCATCTCATCGCCAACTCCCGGTATGACGAGCTGAAGAATGCGGTCAAAGATGCCCTGAACCAATTGACAGGTGCCTATGCTTTGTTAATTCTGACAAACGATTCGCTGTTGGTGGCTCAGGATCCTCACGGTCTGCGGCCGCTGTCCATGGGAATGTTGGGAGATGCCTATGTCTTCTCCTCGGAAACATGTGCTTTTGATGTCATCGGTGCCGATTATCTGCGTGAAGTGCAGCCAGGGGAGCTGTTGGTACTGAATCGTCAAGGATTACGCAGTCTCTCTTTTGCCGAACCGGCTTCCCGGGCGGTTTGTTCCTTTGAGTATATCTATTTTGCAAGGCCGGACAGCGATATTGATGGAATCAATGTCCATTCGGCCCGTAAACAATTGGGAAGGCAACTGTTTAACGAAGCACCGGTGGCGGCAGATGTGGTGACGGGTGTTCCTGACTCCAGCACGTCGGCGGCGATTGGTTTTGCTGAGGCGGCAGGAATTCCTTATGAGTTGGGATTGATAAAAAATCGGTATGTGGGCAGAACCTTTATCCAACCCAGTCAGGAACTTCGGGAACAAGGGGTTAAGATGAAGCTTTCCGCCGTACGCAAAGTGGTGGAAGGAAAGCGGGTTGTAATGATTGATGATTCCATCGTCCGGGGAACGACCAGCCGTCGGATTGTCCGGATGCTGAAAGAGGCTGGAGCAACAGAGGTGCACGTGCGGATCAGTTCTCCGCCGGTAAAATACCCTTGTTTTTACGGGATTGATACGGCGGATCGGGAACAGCTGATCGCTTCCGACCACACGGTGGAGGAAATACGGGATCTAATCGGTGCTGACAGCTTGTACTTTCTCAGTGAACAGGGCTTGATCCGGTCAGTAGGCCGAAGGGGTGCTGTGGATTCATGCGGTCACTGTTTAGCTTGTTTCAATGGGGGCTACCCCACAGTGATTGAAGAGAAAGAATCAGTTCCAGTGGAGGGACGACAAGGATGAGTGAAGCTTACCGCAATGCCGGAGTCGACATCGATGCCGGAAATGAAGCAGTGGAAAGGATGAAGCAACATGTCAGAGGAACCCGTCGTCCGGAAGTGATGGGAGGAATCGGCGGGTTTGGGGGGATGTTTGCCCTTTCCTCCTATGACAATCCGGTGTTGGTGGCAGCCACGGACGGAGTGGGTACCAAATTGAAGCTGGCATTTGCCCTGGATCGTCACGATACGATTGGAATAGATTGTGTGGCCATGTGTGTCAATGATCTGGTGGTGCAAGGGGCAGAACCGCTTTTCTTTCTGGATTACATCGCCACAGGAAAGCTGAACCCGGATCAGGTGGAAGCCGTTGTGAAGGGAATTGCTGCCGGTTGCCGACAAGCCGGTTGTGCCTTGATCGGGGGAGAAACGGCAGAAATGCCCGGAATGTATCCTGTCGGGGAGTATGATGTGGCCGGTTTTGGTGTGGGAGCCGTGGAGCGGGATCAGGTGATTACGGGAGAACGGATTCAACCGGGGGATGTGATTATCGGTTTGGCTTCCAACGGTTTACACAGTAATGGCTATTCCCTTGTCCGCCATGTTTTAGTGGATGGGCAGGAGGAAAGGCTGTCACAGCAAGTTCCCTGGGGCCCATTTACCTGGGGGGATGTGTTGCTGGCCCCCACTCGCATTTATGTTCCGACATATAGAGCCTTGATGCACCATTTTGATGTAAAAGGTGGAGCCCATATTACCGGTGGCGGATTAGTGGAAAATGTTCCCCGGATGCTCCCGGAAGGGTGTCAAGTGGAACTGGATCTGGATTCCTGGCCTGTTCCGGAGCTGTTCCGCCATTTGGGCGAAATGGGTCAGCTGACAGATGAGGATTTGTTTCGTACTTTCAATATGGGAATCGGTATGACTCTCTATCTGCCGCCGGAGCAGGCGGAAGCTGCTGCGGAGTTGGCGGAGGAAATGGGAGAGAAGGCTTACTTGATCGGACGTGTTGTGGAAGGTAAAGGCGATTTGGTTTGGAGGAGGAAGGGTTCATGAGTATTGCTGTTTTTGCATCAGGAGATGGAAGCAACTTTGAAGCATTGGTGGAACGGTCCCGGAACCTTCAATGGCCACAGTCCATCACTCTGTTGGTGACGGATAAAGCAGATGCCGGAGCACTGGACAGGGCCCGAAAGTTGGGGATTTCCGCAGTTACAATTCGGCCACAAGATTATGAAAGCAAGGAGGCCTATGAATCGGTACTGTTGTCCCTTCTGCGGGAAAATGGCATTGAATGGATTCTGCTAGCCGGTTTTATGCGGATACTGGGCCCTGTCTTATTAAAGGCTTATCCTTGGCGGATCTTGAATGTCCACCCGTCTCTCCTTCCTGCTTTCAGGGGAAAGAATGCTTTGGAACAGGCCCTGGCTTACGGTGTTCGTTGGAGTGGAGTTACCGTGCACTGGGTGGATGAAGGAGTGGACACCGGTCCCATTATCGATCAGAAGCCCATCTTGGTGGAACCGAATGACACAGTGGAAACTTTGCAAAGGAAGGCTCAGTTTGTAGAGCATAATCTGTATCCCGCCGTTGTTTATAAATTGTTGACGGGGAAGATACAACCGCCACAGGGAACACCGGCTGACTGACGACGAAACAAGGAGGAATATTTCATTGAACCGTATTCGACGTGCGCTGATCAGTGTATCCGACAAAAGTGGCATCCTGGAACTAGCCCGTCAACTGTCAAAGCAGGGCGTGGAGATTGTTTCCACGGGGGGGACTCGACGGAAACTGACAGAGGGTGGCGTTCCGGTAATCGGGGTCTCTGAATTGACGGGATTTCCGGAGATTCTGGATGGGCGGGTGAAAACCCTGCATCCCCGTGTTCATGCAGGCTTGTTGGCACAACGGGATTCAGAAGATCATACACGCCAGTTACAGGAACATCAGATTTCCTTGTTTGACCTGGTTGTGGTCAATCTGTATCCCTTTGAACAAACCGTGACAAAGGGAAATGTCACGATGGAAGAGGCAGTTGAAAATATAGACATTGGGGGCCCCTCCATGGTACGGGCTGCTGCCAAAAATCATCGTTATGTCACAGTTTTAGTGGATCCTCGTGATTATGCCGATGTAATGAAGCAGGCGGAGACAGGGGGAGTAACGGCGGAAACCCGTCGAAAATTGGCAGCCAAGGCTTTTCGCCACACTGCTGCATATGACACCTGGATTGCCCGTTATCTCAGCGAACAGACAGGGGAGGAATATCCTGAAAAACTAACGGTTACCTACGAAAAAGTACAAGATCTTCGCTATGGAGAAAATCCTCATCAAACTGCTGCATTTTATCGCCAGCCTCAAGATAATCAGGTATCCGTGGCGACTGCAAAGCAGTTACATGGTAAAGAGCTTTCCTATAACAACATCCATGATGCCAATGCTGCGTTGGAAATCCTGGCGGAGTTCGACGAACCGGCGGCAGTGGCAGTGAAGCATGTAAATCCCTGTGGAGTCGGTGTGGGGAAAGATAGTGCGGAAGCCTTCCGGAAAGCCCATGATGCGGATCCAGTTTCCATCTTCGGTGGGATTGTAGCTTTCAATCAGATTGTGGACCGGGATACTGCTTTGCAATTAAAGGAAATATTTTTGGAAATTGTGCTGGCTCCGGCTTTTTCCGATGAGGCCCTGGATATTCTGAAGGAGAAGAAAAATATTCGACTCCTGCAGACAAGGACAGGAAATAAAGATGAAAATCATGATTGGAAGCTGTTGACCGTACAAGGTGGACTGCTGGTACAGACAAGGGACCGAAAACAGACGGTCCGGGAAGAATGTGAAGTTGTTACCCGTCGCAAACCTTCAGAAGCGGAATGGGCAGAGCTTCTGTTTGCCTGGAAAGTGGTAAAACACGTCAAATCCAACGGAATTGTCCTGGCAAGGGACGGTTGTACCGTTGGTGTCGGAGCGGGTCAGATGAATCGGGTGGGATCTGCCAGGATCGCCATTCAACAGGCGGGTAATCAGGCAGATGGGTCGGTACTCTCCTCCGATGCCTTCTTTCCCATGAAGGATACCGTGGAAGAAGCGGCAAAGGCGGGGATTACCGCTATCATCCAACCAGGGGGGTCTGTCCGGGATCAGGAATCCATTGAAGAAGCAGATCGGTACGGAATCGCCATGGTGTTTACCGGGATCCGTCACTTCAAACATTAA

Protein sequences of DBSCAN-SWA_1

>NZ_CP048104|531878:541853|538658_539693_+|WP_173220237.1|DBSCAN-SWA
MSEAYRNAGVDIDAGNEAVERMKQHVRGTRRPEVMGGIGGFGGMFALSSYDNPVLVAATDGVGTKLKLAFALDRHDTIGIDCVAMCVNDLVVQGAEPLFFLDYIATGKLNPDQVEAVVKGIAAGCRQAGCALIGGETAEMPGMYPVGEYDVAGFGVGAVERDQVITGERIQPGDVIIGLASNGLHSNGYSLVRHVLVDGQEERLSQQVPWGPFTWGDVLLAPTRIYVPTYRALMHHFDVKGGAHITGGGLVENVPRMLPEGCQVELDLDSWPVPELFRHLGEMGQLTDEDLFRTFNMGIGMTLYLPPEQAEAAAELAEEMGEKAYLIGRVVEGKGDLVWRRKGS
>NZ_CP048104|531878:541853|534066_534318_+|WP_173220234.1|DBSCAN-SWA
MIKATIVIRLKSSVVDPQGHAVKGSLHSLGFEEVQDVRIGKMIEVWLESADLEAAKVKVEAMCKQLLANPVIENYEYQLEEEA
>NZ_CP048104|531878:541853|540311_541853_+|WP_173220239.1|DBSCAN-SWA
MNRIRRALISVSDKSGILELARQLSKQGVEIVSTGGTRRKLTEGGVPVIGVSELTGFPEILDGRVKTLHPRVHAGLLAQRDSEDHTRQLQEHQISLFDLVVVNLYPFEQTVTKGNVTMEEAVENIDIGGPSMVRAAAKNHRYVTVLVDPRDYADVMKQAETGGVTAETRRKLAAKAFRHTAAYDTWIARYLSEQTGEEYPEKLTVTYEKVQDLRYGENPHQTAAFYRQPQDNQVSVATAKQLHGKELSYNNIHDANAALEILAEFDEPAAVAVKHVNPCGVGVGKDSAEAFRKAHDADPVSIFGGIVAFNQIVDRDTALQLKEIFLEIVLAPAFSDEALDILKEKKNIRLLQTRTGNKDENHDWKLLTVQGGLLVQTRDRKQTVREECEVVTRRKPSEAEWAELLFAWKVVKHVKSNGIVLARDGCTVGVGAGQMNRVGSARIAIQQAGNQADGSVLSSDAFFPMKDTVEEAAKAGITAIIQPGGSVRDQESIEEADRYGIAMVFTGIRHFKH
>NZ_CP048104|531878:541853|537234_538662_+|WP_173220236.1|DBSCAN-SWA
MRNESDFDELKEECGVFGIVGHPDAAELAYYGLHALQHRGQESAGIVATDGTGFRYHRSMGLVHEVFNRDILEGLKGSTAIGHVRYSTSGESLLTNAQPLVFHHEKVGQLALATNGNLVYAARQKKELEAQGAVFHTTSDTEVIAHLIANSRYDELKNAVKDALNQLTGAYALLILTNDSLLVAQDPHGLRPLSMGMLGDAYVFSSETCAFDVIGADYLREVQPGELLVLNRQGLRSLSFAEPASRAVCSFEYIYFARPDSDIDGINVHSARKQLGRQLFNEAPVAADVVTGVPDSSTSAAIGFAEAAGIPYELGLIKNRYVGRTFIQPSQELREQGVKMKLSAVRKVVEGKRVVMIDDSIVRGTTSRRIVRMLKEAGATEVHVRISSPPVKYPCFYGIDTADREQLIASDHTVEEIRDLIGADSLYFLSEQGLIRSVGRRGAVDSCGHCLACFNGGYPTVIEEKESVPVEGRQG
>NZ_CP048104|531878:541853|539689_540286_+|WP_173220238.1|DBSCAN-SWA
MSIAVFASGDGSNFEALVERSRNLQWPQSITLLVTDKADAGALDRARKLGISAVTIRPQDYESKEAYESVLLSLLRENGIEWILLAGFMRILGPVLLKAYPWRILNVHPSLLPAFRGKNALEQALAYGVRWSGVTVHWVDEGVDTGPIIDQKPILVEPNDTVETLQRKAQFVEHNLYPAVVYKLLTGKIQPPQGTPAD
>NZ_CP048104|531878:541853|533354_534074_+|WP_173220233.1|DBSCAN-SWA
MNKGEMLYEGKAKKVYLTEDPAQAWVEYKDDATAFNARKKGAITGKGELNNQISAFFFRFLGEQGIPHHFIQTLSNREQLVKKVAILPVEVVVRNRVAGSLAKRLGLEEGMTLSVPIVEFYYKSDELDDPLITEDHIRLLQLATTDQVNQMRKMALDVNGHLQKLMAAKGIQLVDFKLEFGLDNEQRLLLADEISPDTCRFWDTATGKKLDKDRFRRDLGDVEGAYREIWNRLGGEAHD
>NZ_CP048104|531878:541853|531878_533174_+|WP_173220232.1|DBSCAN-SWA
MIERYTRREMGRIWSDENRYQAWLEVEILACEAWSELGVIPQGDVAQIRKNAEVDVKRILEIEEQTRHDVVAFTRAVAETLGPESKWVHYGLTSTDVVDTAQSYLLKQANEILLKDVDRFLDVLKKKALAHKDTVMMGRTHGVHAEPTTFGLKLALWYTEMKRNRERLVQAAENVAVGKISGAVGTYANIDPFVEEYVCRKLGLTPAPVSTQTLQRDRHADYLSTLALIAASLEKFAVEIRGLQKSETREVEEAFGKGQKGSSAMPHKRNPIGSENITGLSRVIRGHMVTAYENVALWHERDISHSSAERVILPDSTILLNYMLNRFAGIVENLTVFPENMKRNMDRTYGLIYSQRVLLTLIQKGLKRERAYDQVQKLAMQAWEEACSFRELVERDKTIMEYLTPEEVEDCFDYRFHLKRVDEIFSRAGLL
>NZ_CP048104|531878:541853|535081_537265_+|WP_173225087.1|DBSCAN-SWA
MTTEEFEQVQQHLGRLPNWTELGIYSVMWSEHCSYKNSKPLLRRFPVSGSKVLQGPGEGAGAIDIGEGQAVVFKIESHNHPTAVEPFQGAATGVGGIIRDVFSMGARPVALLNSLRFGSLDSDRARYLFGRAVAGIAHYGNRMGVPTVGGEVEFDEGYDDNPLVNAMCVGILPHKDLQKGIATGTGNPVIYVGASTGRDGIHGATFASEELSEDSGDKRPSVQAGDPFMEKLLLEACLELVEKEVLLGIQDMGAAGLTCSSAEMAAKGDAGMELNLDHVPQREAGMTPYEMMLSESQERMLLVVEKGREGEVQEVLDKWGLQSAVVGRVTDDQRYRIRFQGEIVADIPVKTLVDDAPVLTRTGSVPQYYKDFAEKTFEPELAEVNPEDALQKMLASPNIASKRWVYQQYDHMVGTSTAVRPGSDAAVIVLDGTDKALAMCTDGNSRYVYLDPRHGGAIAVAEAARNVVCSGAQPLAITDCLNFGSPEKPEVYWQLEEAINGMSEACRTLETPVVGGNVSLYNETGGQPIAPTPVVGMVGLIDSRDHITTQGFKKEGDTLLLLGETQLELGGSELQHQVIGKISGRPPSVNLETEKLLHDLVLEAIRKGWVSSAHDLSSGGLAVALAESAISGSMGAEVQLELSLAPSLFLFSESQSRILLSVASHEAENMQELARLRNVPCTKIGKTGGDRLQVKIGGTSVIRLAVEEMRTIWEGAIPCAMNPTSTN
>NZ_CP048104|531878:541853|534318_535002_+|WP_173220235.1|DBSCAN-SWA
MRFAVPVFPGSSCDMDCIKAVKEILNHPADPVWHNDRNLDSYDAIILPGGFSYGDYLRAGALAQCSPVMEGVRKAVDQGKLVIGIGNGFQLLLEAGLLPGAIRVNDHLQFRCAMQGLKVENNTLPFTLDYHAQEEIVLPIAHGEGNYYCDDKTLHQLEESGRIVFRYIKGNPNGSVGDIAGIVNEQGNVLGMMPHPERAIREWMGSKDGVRLFTSMLHYWGEKHGAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173220232.1|531878_533174_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	9.1e-20	32.2
WP_173220233.1|533354_534074_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D8KNF0	Synechococcus_phage	1.0e-44	42.8
WP_173220234.1|534066_534318_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	5.3e-09	39.2
WP_173220235.1|534318_535002_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_173225087.1|535081_537265_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	7.5e-168	44.8
WP_173220236.1|537234_538662_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.6e-55	33.8
WP_173220237.1|538658_539693_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.1e-71	44.0
WP_173220238.1|539689_540286_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.6e-27	37.5
WP_173220239.1|540311_541853_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.2e-72	48.6

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP048104|867754:880104|DBSCAN-SWA
CATGGAGAAAGATAACCTATTGGAAGTACGGGACCTGCATGTTTCCTTTGATACGTACAATGGTGAAGTCCAGTCAGTCCGAGGTGTCAGTTTTACTGTCGCAAAGGGTGAGACTCTGGCGATCGTGGGAGAATCCGGGTGTGGAAAAAGTGTCACATCTCAAAGTATCATGCGCTTGATTCCGGAGCCTCCCGGAAGAATCAAGTCAGGTGAAGTACGGTTTGAAGGAAAAGATCTCACCAGGTTACGGGACAAGGACATGGAAGAAATCAGGGGAAAAGAGATTGCAATGATCTTCCAGGACCCGATGACCTCTCTGAATCCCACCATGACAGTGGGTCGTCAGATTACCGAGGGATTGGTGAAACATCAGGGTCTCAGTAAAGAGGAAGCCAGAAGAAAGGCGGTGGAAATGCTGGAGATGGTGGGTATTCCAAGCCCACGTTCCAGGATTAAGCAGTACCCTCACCAATTTTCCGGAGGCATGCGACAAAGAGTGATGATTGCGATTGCACTGGCATGTTCACCCAAGCTGCTGATCGCAGATGAACCGACAACTGCTCTGGATGTAACGATCCAGGCCCAGATCCTTGAGATCATGAAGGATTTGCAAAAAAAGCTGGATACCTCCATTGTTTTAATTACCCACGATCTGGGTGTTGTGGCAGAAATGGCGGATCGAGTGGTAGTGATGTATGCCGGAAAAGTGATGGAAACGGGAACAGTGGAAGAAATTTTTTACCGTTCCCGGCATCCTTATACTTGGGGATTGATGGAATCAGTTCCCCGGCTGGATTTATCCAGGGGCCAAAATCTTACGCCAATTAAGGGAACTCCACCGGATTTACTGAATCCGCCCCAGGGATGTCCATTTGCTGGGCGTTGCCAGCATGCAATGAAAATATGTAAGATAGAATTACCGGAAACAACGGATTGCTCCGATACCCACCAGGTAGCCTGTTGGTTGGAACATCCGCTGTCACCCGATGTATCAGCGCCATATGAAATGGTAGGAGGGGGTTGCAAATGAGTACTGCTGAACCGAAAACGGAAAAGATTCTCGAAGTCAATCAAGTCAAAAAGCATTTTGATATGGGACGCGGGCAAGTTGTCCAAGCAGTAGATGACGTAACTTTTCATGTATACAAAGGTGAAACCTTGGGTCTGGTTGGAGAATCCGGTTGTGGGAAATCCACGATGGGTCGTACCATCATACGTCTTTACGAAGCGACGGACGGGGAGATTAAGTTTAAAGGGAAAAACACCAAAAATCTGAGTGGGAAAGAACTTCACCAGTTTAACAGGGAGATGCAAATGATCTTTCAAGATCCCTATGCTTCTCTCAATCCTCGGATGACGGTGGGGGATATCATCGCAGAAGGGTTGGATATCCACGGATTGGCCAAGGGTAAAGAAAGACGGGAAAAAGTGGTGGAGCTTTTGAGAACCGTCGGTTTGAATGAAGAACACGCCGACCGTTTTCCCCACGAGTTTTCCGGCGGTCAACGGCAACGAATCGGGATTGCCCGGGCTTTGGCGGTAGAACCGGACTTTATTATCGCTGACGAACCGATCTCGGCATTGGACGTTTCCATTCAAGCTCAGGTTGTTAACCTGATGAAAAAATTACAACGGGAAAAAGGCCTCACCTATCTGTTTATTGCCCATGATCTCTCGATGGTGAAATACATCAGTGACCGGGTAGGAGTAATGTATTTGGGGAATCTGGTGGAGCTTGCTGACAGTCAGGAGTTATACGATCATCCTCTTCATCCCTATACGGAAGCTCTGTTGTCAGCGGTTCCAATCCCGGACCCTGACACCGATGAGCGACGGGAACGGATTATTTTGAAGGGAGATGTACCCAGCCCCATCGATCCGCCCAGTGGTTGCCGGTTCCGGACTCGGTGCCCCAAAGCGATGGACATATGCGGGCAGGAGGTGCCAAAGTGGCAAGAGGTGCGCCCCATGCACTGGGTGGCTTGTCATCTGTATCAGGAAGAATCCATGAAAAAAGAAAACAAGGAGAAAAGCTCCCACTAAGTCCCGTCAACTCCATTGAGATGAAGCCCTTCGATCCGGATTGGACTGGGGTGTAGGGATCTTCCGATGGATCGGTGTATCTGAAGTGCTGCTAAAAAGGCCTGATTTTCCAAATGTGTTTCTTTTATCTGTCTTACTGAAGACAAAACCGCTTCTTTAATAAGAAGCGGTTTTGTCTATCTGTTAGAGTACTTGTTCTACCTCTGTCACACCGGGTACTTCTTCAATGAGAGCACGCTCAATTCCGGCTTTCAGAGTAATGGTGGAGCTGGGGCAGCTGCCGCATGCACCAAGCAGGCGGACCCGAACGATGCCGTCTTCCACTTCCACCAGTTCCACATCTCCTCCGTCACGTTGAATGAAGGGACGCAGTTTATCCAATACTTCTTCCACTTGTTCTTCCATGGGTTTAAAACTCCTTTCCTTTAAGAACGGTTGCACGATAACCCTGATTCCTCTAGGGACATTGTAGCATGTTTATAACGATGGAGGAATGTCTGATTGAAAAGGTCCTTATCCATATTATATTAAATTCCCATTGAATTGTCTCCTCATTCAGGTGGGAAAATCAGCAAATGGGAGGGGCTTTGCTTTTGAATACTTTTCACAGGGTCTTACAATCGTGGTAAGATAAAAGAGACAAAAGAATAAACGACAGGTTCTTTTACTGCTGAAAGTGTTGTATGGCACCACCTGATAACAATGCTTTGGTGGCTGACTGAGTCAAAGGAAACAGACCTGTCATACTCGTCGTGTATCAATCGTTTTGACTTTTCGGGGAAGAGGGATTGTCATCATGAAACAGGTCTTTGGGAATATCAAGGAGTTAATCGGAAACACACCGATTGTACGAGTAAATGGTTTTAAACTGCCTGAGGGAGTCCGGATTTTCGCAAAACTGGAATATCTCAACCCTGGCGGCAGTGTGAAGGACCGTCTCGGCATGGCTCTGATTCAAGCTGCTGAGCGGGAGGGGAAACTGAAACCTGGCGGAACGATCATTGAACCTACTGCGGGTAATACGGGGATCGGCCTGGCACTGGCTGCCGTGGGAACCGGTTATCAGGTAATCTTTGTGGTTCCTTCTCGCTTCTCTGAGGAAAAACAGGAACTGATGCGTGCACTGGGTGCCAAAGTGGTAAATACTCCCCGTGAATTGGGGATAAAAGGGGCCATCGCGAAAGCCAAGGAGTTGGAACAAGAGATCGAAGGTTCTTACTGCCCGCAACAGTTTGCCAATCCGGCCAATCCAGAGGTTCATTATCAGACAACGGGTCCTGAAATTTGGGATCAGATGGAGGGTCGGGTGGATGTGTTGGTGGCAGGAGCCGGCTCCGGCGGAACCTTTATGGGTGTCGCCCGCTATCTGAAAGAACAGAACCCGGATGTGAAAACGGTGATTGTGGAGCCTCAGGGGTCCATTTTAGGCGGGGGAGAACCCGGGCCTCACAAAACAGAAGGTATCGGGATGGAGTTTTTGCCGGATTATATGAATCCAGCCTACTTTGATGCCGTTCATACTGTATTGGATCGGGATGCTTTTAAAATGGTACGGGAGTTGGCCTCTCGGGAAGGGATGCTGGTGGCCAGCTCGTCAGGAGCGGCATTTTACGCTGCCCTCCAAGAGGCAGAATCCGCCTCAGCCGGCACCAATATTGTCGTTTTGTTTCCTGACGGCAGTGATCGGTACTTAAGCCAAAATATTTACCAAGAGGAGGTATGACCGTTGCGCATGGATACGAAATTGATTCATGGTGGCGTCTTCGGAGATGATAAAACAGGTGCGGTAAGTGTGCCCATTTATCAGGTTTCCACATATAAACAAGAAGGTATCGGACAACATAAAGGTTACGAATACTCCCGAACGGGTAATCCTACCCGGGAGGCTCTGGAAATTCTGATTGCAGAGTTGGAAAACGGAACAAGAGGTTTTGCCTTCTCTTCAGGTATGGCCGCCATTTCCACGGTTGTGGCTCTGTATAAGCAAGGAGATCATCTCATCATTGGAGATGATACTTATGGAGGTACCTACCGTGTGATGAGCAAGGTATTTAATCAATTGGGGATAGAGGCTTCCTATGTGGATACGAGTCGTCCGGAGCTCATCACAGCTGCAATCCGTCCCCATACCAAGGCTGTCTTTGTGGAAACCCCCAGTAATCCTTTGCTCAAGGTAACGGATATGAAGAAAGTGGCAAATATTTGCCGGGATCATGGACTTCAGTTGATCGTGGATAACACCTTCTTAACTCCCTATTGGCAAAATCCCCTGGATTTTGGGGCAGACATCGTGATTCACAGTGCCACGAAATATCTGGGGGGACACAGTGATGTAGTGGCAGGTCTGGTGGCGGTAAAGGACCCGGAGTTGGGAGAGGCCATTCATTTTGTGCAGAATTCCATGGGCGGTATTTTGTCTCCTCATGATTCATGGCTGTTGATGCGGGGAATGAAAACCCTTGGTCTTCGGATGCGGCAACATGAATCCACGTCTAATCGTCTCGCCCGCTGGCTTTCTGAGCGAAATGACATCAAATCGGTTTATTATCCCGGATTACCGGATCATCCCGGTCATCAGACAAATCTTCAGCAAGCCAGAGGCTTCGGAGGTATGATTTCTTTTGATGTCGGTTCAGGGAAGCGAGCGGAACAAGTACTGTCCAAAACCCGGTTCTTTACGTTGGCGGAAAGTCTGGGAGCTGTGGAGAGTTTGATTTCCCTTCCCGTTCACATGACTCATGCGTCGATTCCCGAGGAACGCCGCCGGGAGCTGGGAATTACGGAGGGACTGATTCGAATATCCGTAGGGGTGGAAGATCCGGAAGATCTGCTGGAGGATTTGGATCAGGCTCTTCGCTGATAAACAGGAGGTATGAAATGTGAGTCAACCCACAGAAGTCCTTGTCTATGGGGCGGAAGAAAGATGTGCCAGTTGTGTTAATCTGCCCTCTGCTGAGGAAACAGCTTCATGGCTGCAAGCAGCTTTAGGACGAAAATATGGGGATCAGGTTCAGGTTCGCTATGTGGATATTTATCAGCCGAACGGGGCGAAGGAAACCGCATTTTCCAGGAGGGTACTGGAAGAGGATATTTGGTATCCTGTTATCGTCATCCAAGACGAAATCGTGGGAGAAGGAAGTGCTCGTTTAAAAGATATTCAAAACAAGCTGGAGGAGACGGGAGTAACGGCTCTGACAGAGAAGTCCCTGTGAATGGAGTTACAAGCCCCTGTTGCGATCTGCCACAACAGGGGCTTGTCATATCAGTGACGTTTTTTGTTTTGAATTTCAATGCGTCTGGGTGCCTGCTTTTGATCCTTGGGAACGGTGATATGCAGAAGCCCGTTGTCACTGTCTGCCGTAATGGCATCCATGTCGGCATCTGAGGGCAGTGTAATCACACGACGGAATGAGCCATACTGACTTTCTACCATGTGAACCTGTCCTTCTTGTTCCTGTTCTTTTTTTCGGTGCTTTTCTCCCCGAATGGTTAAAGTGTTCCCATGTACTTCGATCTGAATATCCTCAGGTGTGATTCCGGGTAATTCAGCCTCAACATGATAATGATCCTCATGTTCCTCCAGGTTAAAGGCAGGTTGAAATAATGAAGAATCCCCCCGAAAAAAAGGGGAATCAAAAAATCGGCTCATCATCCGTTCCATCTCTTGTCGAAAAGGATGAATCGGATGCTCGTTATGAGCATTAAAACGGTTGATGGAACCCATTATCCATCACTCCCTCTGCTTTTTCTTTCGTAAACAGTATGGATCAATGGAATGAGTTTCATTCTGTTGTTTTTAAGGTTTCTGTTTTTTTACTGTCAATTAAGTCCCCTCGGATGACATAACGATCCGGAGCACTGCCGACCATGTTAAAGGGATAGCAGGTAATCAGAGATATATCGGGTTTGTCATGGGCCACGATAACCGATCGATCCTCGGCGTCTGTGATCCATGTTTTTCGAATCTGGTAGGTATGGGTCCAACCATATGCTTTTATATACAGTTTATCCCCTTCTTTTAATTCTCCTGCTCGACGAAATACGGTTTCCCGGTGTCCGGCCAATACAGCATGTCCGGTTTGACCTGGAAGAACCGTTCCATAACCGACATACTGACCCACCCCCTTGGCTAACTGTTCCTCCTCTGTGCCGTAAACAATGGGGAGTATTGCACCAATACGAGGGATGATCAACTCCCCTACGGAATCTCCTTTTCGAGGTTGTCGATCTGTATCTTCTCCCTTGGTCTTGGAAGGTTTTGCTTCGGTATCGTCCCAATCCTTTGCGATGGCCATGGCCAACTTCGGATCGTGAACCGCCACACTGATTTGATCCCACCATTGATACGCATGATACAGGATCATGGATGCTCCGAAGAAAATCAATGTGTAAGCCAGGATGCGATTCATTCTATTTCCCTCCTGGACTTTATGAAATGGTTATAATGGCTTTTATCCTATCATGAATTTCTAAAAGGGAATAGATGATTTTCAGAAAAAATCTTACCGTAACGGTAAATATCGGGCAGGTTCCTCATCTTGGGAGAGATCAAAGGTTATAAGTATTTTTCTAATTTGACAGTAATCGGAGAATCGTTCATCATTAAATGTAAAGATATCCGCATTATTTCTAATAAACATTATATTGACTATTAGAAATATTATATTAAAATACACTGTATATAAAGATTAAGGAGGATGATAGTCAGAAAAGGACGTGGTACTTGTTTACTCAAGACTTTCCTTTGAAGTGGGTACCAGGTGAGAAAGGAGGATACTTTCTCCACTGAGGAGAGAAGCAACCTCTTCGTTAAGGATGCAGCTCATCTGATCCCAAATGTGGTGATTGTGAAAACGTATTCCATGGTTCGGTATATTTTCAAACATGCACTGCTATTGAATCGTTTTGGCTTGTGTAAAAAGGGATGATCTGGGGGTTGTATCACTTTAACTTCATAGGGAAATAAGAGGTGATTACGCCATGGGAACAACAGAAACCGTAGGAACGTTGGTTGATGCATTAAGGGAAAATGCATCCAGCATGCCGGATCATCGTGCATACTCCTTTCTGGTTGACGGGGAACAAGACAGAATGGATATAACGAGTGCGGAGTTGGATGCTCGCTCAAAAGCGATTGCGGCAGCTCTGCAAGGTTGTGTTGCTAACTCAGAACGTGCATTGTTGCTTTTTCCCCCAGGATTGGACTTTGTTGTTTCTTTCTACGGGTGTTTGTATGCAGGAGTATGTGCAGTTCCTTGCTATTTGCCCTCTGTCCCCCGGGCCAAGAGCAATTCGATGTTGGACCGGTTTGTTACTATCGCCCGAGATTGCAATGCTTCCGTGATTTTAACCACTTCTGAATTAATGGACAAGCTACAGGAACGTTGGCGGAAGTTTGAATTGGACACAGACATTTTATGGCTAGCCACCGACACCATCCATGAAAACAGGGGACAGGATTGGGTGGAGCCGTCCATCAGCGGGGATACTTTAGCTTATCTTCAATATACATCGGGGTCCACGTCTGTTCCCAAGGGTGTGATGGTCACCCATGCCAATCTGATAAACAATAGCAGAATGATGCAGAAAGCCTCACAATCAACTGCAGGGGTTGAAATTGTCAGTTGGTTGCCGGTGTTTCACGATATGGGATTGATCGGTGCGATTTTGCAATCCCAATTATTGAATGGAAGTTGTACATTTATGACTCCCCAGCATTTCATCAAAAAGCCGATTCGTTGGTTGCAATTGATTTCCCAATGTAAAAATGAGCACATTATCAGTGGAGGACCAAACTTCGCCTATGATTTGTGTGTCAGAGAGATTTCAGAAAAAGATATGGACTCTTTGGATCTCAGCAGGTGGAAAACTGCATTTAATGGGTCGGAGCCTGTTCGTCGTGAAACAGTAGATAGTTTTATCGAAAAATTCAAACGATGCGGTTTCCAAAAGAGTGCGATGCACCCTACATACGGATTGGCGGAAACCACATTAATGGTAAGTGGCCGACAACAGAAAGAGCCTCAGCTGTTTGTCGCTGATGCTGCCCTCCTTGAACAAGGTAAAGCCGTAAAAGCAGATCCCCGAAATAGTCGGACTAAAACACTGGTTGGGTGCGGCTGTTCAGTGGAAGGCCAGGAACTGTTGATCGTGGATCCGGATACACGGCAAATTTGTAAGACTGGAGGTGTGGGGGAGATTTGGGTTTCAGGTCCCCATGTGGCGAATGGTTATTGGAACCAGGAAGCTGCTACAGAAAATGCGTTTCATGCCTACACGGCCACAGGTGAGGGACCGTTGCTGAGAACCGGGGATTTGGGTTTTTTGAATGAAGAGGAACTGTATATTACAGGGCGGATTAAAGAGGTTATCATCATCCGTGGAAGAAACCTGTATCCCCAGGATGTTGAAAGAAGTGCCGGACGCAGTCATGACAGTCTCCTTGCCGGACTGGCTGCAGCTTTCGCCGTGGAAGTGGAAGGGGAAGAACGCTTGATTGTCGTTCAAGCGGTTAATCGTAGAAGTGATGCAGATTTTTCAGAAGTAGCCAGAAAGATCCGTGAAAACGTTTCGGAAGATCATGATGTTGAACTGTACGGAGTCGTGTTGGTGAAACCTTCGGAAATCAAACGGACAACCAGCGGTAAAATCCAACGCTCCTTATGTCGTGACGCCTTCCTCAATGAGAGCCTGGAAGTGATCGCACAGAGCATGCTGGGGCATGATGAGAATGAGAGGGAAGATGAATTATCCCGGAAATATCTTTTGGATCTGGAGCCGATGGAACGGCGATCTGTTTTGGAAAAGCATCTGAAGAAAAAAGTAGCGGATAAGTTAAAGGTTCCCTCCTCCTCTTTTGGGATGGACACCTATCTGACTTCTCTCGGTATAGGTTCTCTCAGTACTTTCGACCTTCTTGGCAGTCTGGAAAGACAATTAGACGTGAAACTGACCATGGGTGAAACTTTAAACGATGTGGTAAATGAAGTACTGGAACAGCTTGAGGCAACTCCGGTCTCCTTGCCCAAGGTGGAGGAAGACCTGGAAAATCGGCATCAACCATTTCCTCTAACAGATATTCAGTATGCTTATTTCGTGGGGAGAAGCGGAGCGTTTGAACTGGGACGTGTTTCCACACATGCTTATTATGAGATGGAATCGGAAAACATGGATTTATCGAGGCTGGGACGGGCCTGGCAAGGAGTGATACGCCGTCATGAAATGCTCCGTGCGGTGATTATGCCCAGCGGAGAACAACGCATTATGGCAGAAGACGAAGTCCCTGCTTATGAAATCGTGGAAACGGATCTCAGAGGCGCTTCTCCTGATGAAGTGAATGCTTATCTCCAATCCGTGCGGGATCGAATGTCCCACCTGGTTCGTCCCACTGAGAAGTGGCCGTTATTTGAAATTTGTGCAACCAGACTGGATGATCGTGTCCGTGTGCATTTCAGTTTTGATTTGATCGTGGCTGATGTGTGGAGTTTTCGCATTCTTCTGAAGGAATGGGCGGATTTGTATGAGCAATTGGATACGATATTGCCCCCATTAAATCTCTCCTTCCGGGATTATGTGTTAGCGGAAAAGAAATTGGAGTCCACGGAATTATACGAGCAGTCCCGGAAATACTGGCTGAGTCGTTTGTCACAATTGCCACCGGCGCCTGAGTTACCCATGGTGCAAGCATCTGGACTGGAGGAAAAGCAACCTCGATTTGTCCGAAGAAGCGCATACCTGCCATCGAAAAAGTGGCAAACGTTGAAAGAGCGAGGAGCCAAGAATGGATTAACTCCGTCCCATATTCTTCTGGCCGCATTCAGCCAAATTCTGGCTGCTTGGAGTAAAAACCAGCAATTTACATTGAATGTGACACTGTTTAATCGATTGCCGATTCACCCCCAATTCAATGAGATTGTGGGAGATTTCACCTCGGTGGAGCTGTTGGAGGTGGACCTTCGCAACAGTGGCCGTGGCTTGGAAGAGTTGGCCAAGGATCTTCAAAAGCAGTTGTGGAATGACTTGGAACACAGTTATTTCAGCGGAATTCGTGTGTTGCGGGAAATGACCCGACAGCACGGAGGCGTCAGATCGGTAATGCCGGTGGTATTTACCAGTGCCCTTGGACAAGTGATTGGGGAAGCGGATGACCTGCCGATCAGCCGCCTGGGAAAAGTGGTTTATGGTGTTTCCCAAACACCGCAAGTTTATTTGGATCATCAAGTGTATGAACAGAAAGGTGATTTGGCATTTAACTGGGACACCATTGATGATCTGTTTCCGGCAGGCATGTTGGATGATATGTGGAATGCTTATGTCGGTTTTCTGGAAGATTTGGCTGAACGGGAGGAACTTTGGAAAGAAAGGGATTATCAATGGTTACCCGATGATCAACTGCGTCAACGGGAAGAAGTAAATGCCACTCAAGGAAGGGTTCCGAAGGATTTGTTACAGGCGCCTTTCGCGGAACAAGCGGCGATGCACCCTGATCACCCGGCCCTCATTTCCTCAGAAGGAACACTTTCCTACGAAGAATTGTTCCGGCGGGCCAATCAACTGGGACGCCGGTTGCGGGAAGAGGGAGTCCGTCCCGGTATGTTGGTGGGCGTGGCGATCGGGAAGAGCTGGGAACAAATTGTGGCTGTCTTGGGTGTTTTACAGGCAGGTGGCGCCTATTTGGCAGTAGACCCTGATTTGCCGGAAGAACGGCAGGTTTATCTCCTGGAACACGGCCAGGTGGATGTGGTACTCACCTGTGACGGTCGTCCCATAACAGGGGGTTGGCCGGAACATGTTCAGGTTATGGCCGCTGATCTGAAGGGATGGGAAGGAGCCGAAGGGGATCCGTTGGAACCGGTCCAATCCCCTGACGACTTAGCCTACGTCATTTATACTTCCGGGTCCACGGGTCAACCCAAGGGGGTGATGATCAGTCACCGTGCCGCGCTGAATACCGTTCTGGATATAAACGACCGGTTTGAGGTGGGACCGAAGGATGCGGTATTGGCCTTGTCTGCTCTTCACTTCGATTTATCCGTTTACGATATTTTCGGAATGTTGGCGGCAGGGGGAACGATTGTGTTACCGGAGGCGGAGGCGTCACGGAATCCCAAGCGTTGGCTGGATCTGATGCAAGAACATGATGTGACGATATGGAATTCTGTGCCCGCCCTGCTGGAGATGTTGGTGGAGCAGGCCTCAGGGGAAGCAGTTCCCCCCTCTCTGGCATTGCGGCAAGTGCTGCTCAGTGGAGACTGGATCCCGGTTTATCTGCCTGATCGGATAAAAAGCTTGATAAAAGGAGTGCAAGTGGTCAGCTTGGGAGGGGCAACTGAAGCTTCGATCTGGTCGATTTTCTACCCCATTGGGGAAGTGGACTCGAAGTGGGAGAGTATTCCTTACGGGAAGCCCTTGACCAATCAGACATTTGCGGTGCTGAATGAACGGATGGAACCGTGTCCGGTGTGGGTGCCGGGACAACTTTACATCGGAGGTTTGGGGCTGGCAAAAGGTTATTGGCGGGATGAAGAGAAGACAGCAGCCCACTTCATCGAGCATCCGGAGACTGGCGAGCGGTTGTACCGAACAGGGGATCTGGGACGATATTTGCCGGATGGAAACATTGAGTTTTTAGGCCGGGAGGATTTTCAAGTGAAAGTGCGGGGACATCGGATTGAGCTGGGAGAGATCGAATCAACACTGGTTCAACACCCGCAAGTCAAGCAGGCAGTGGTGGCAGCGGTGGGAGCTGATCGAAACCACAAGCAATTGGTGGGCTACGTGGTTCCGAAGATAAAGCAAAAAGGTCAAAACATGAATCAGACAATTACTGAGTTTTTAAGCAAAAAGCTTCCGAGTTACATGATCCCTCAAGGGTATGTCATGTTAGATGAAATCCCGCTTACCCCCACCGGTAAAGTGGATCGAAAAGCATTAGGTCAATTGACCAACTGGCGTCAAACCCCGGGAACTGAGTATGAAGCACCGAGAAACGAGATTGAAAAAACCATCTCCAATACATTGCAACGCATTCTGGAGGTTGAAAAAATAGGAATCAACGACAATTTTTTCGACTTAGGGGCCGATTCGGTTACTGTGACCCGGGCGTACCGACATCTCAAGGAGGATTTATCAAGGGATTTTTCGCTGTTGTCATTTTTCGAATATCCCAGCGTAAGACTCTTGGCTGCTCACCTCAGTGGGGAGGCAAATGAGCAGTCTGCTGTGCAACAAGGTTCGGAACGAGCCCGAAAAAAGCGTGCGGCACAAGTTAACCGGAGGAATAAAAAGCGCTACAGAAGCGGGGGATGA

Protein sequences of DBSCAN-SWA_2

>NZ_CP048104|867754:880104|872675_873008_+|WP_173220821.1|DBSCAN-SWA
MSQPTEVLVYGAEERCASCVNLPSAEETASWLQAALGRKYGDQVQVRYVDIYQPNGAKETAFSRRVLEEDIWYPVIVIQDEIVGEGSARLKDIQNKLEETGVTALTEKSL
>NZ_CP048104|867754:880104|873578_874205_-|WP_173220825.1|DBSCAN-SWA
MNRILAYTLIFFGASMILYHAYQWWDQISVAVHDPKLAMAIAKDWDDTEAKPSKTKGEDTDRQPRKGDSVGELIIPRIGAILPIVYGTEEEQLAKGVGQYVGYGTVLPGQTGHAVLAGHRETVFRRAGELKEGDKLYIKAYGWTHTYQIRKTWITDAEDRSVIVAHDKPDISLITCYPFNMVGSAPDRYVIRGDLIDSKKTETLKTTE
>NZ_CP048104|867754:880104|874556_874724_+|WP_173220827.1|DBSCAN-SWA
MRKEDTFSTEERSNLFVKDAAHLIPNVVIVKTYSMVRYIFKHALLLNRFGLCKKG
>NZ_CP048104|867754:880104|867754_868783_+|WP_173220813.1|DBSCAN-SWA
MEKDNLLEVRDLHVSFDTYNGEVQSVRGVSFTVAKGETLAIVGESGCGKSVTSQSIMRLIPEPPGRIKSGEVRFEGKDLTRLRDKDMEEIRGKEIAMIFQDPMTSLNPTMTVGRQITEGLVKHQGLSKEEARRKAVEMLEMVGIPSPRSRIKQYPHQFSGGMRQRVMIAIALACSPKLLIADEPTTALDVTIQAQILEIMKDLQKKLDTSIVLITHDLGVVAEMADRVVVMYAGKVMETGTVEEIFYRSRHPYTWGLMESVPRLDLSRGQNLTPIKGTPPDLLNPPQGCPFAGRCQHAMKICKIELPETTDCSDTHQVACWLEHPLSPDVSAPYEMVGGGCK
>NZ_CP048104|867754:880104|871528_872656_+|WP_173225173.1|DBSCAN-SWA
MDTKLIHGGVFGDDKTGAVSVPIYQVSTYKQEGIGQHKGYEYSRTGNPTREALEILIAELENGTRGFAFSSGMAAISTVVALYKQGDHLIIGDDTYGGTYRVMSKVFNQLGIEASYVDTSRPELITAAIRPHTKAVFVETPSNPLLKVTDMKKVANICRDHGLQLIVDNTFLTPYWQNPLDFGADIVIHSATKYLGGHSDVVAGLVAVKDPELGEAIHFVQNSMGGILSPHDSWLLMRGMKTLGLRMRQHESTSNRLARWLSERNDIKSVYYPGLPDHPGHQTNLQQARGFGGMISFDVGSGKRAEQVLSKTRFFTLAESLGAVESLISLPVHMTHASIPEERRRELGITEGLIRISVGVEDPEDLLEDLDQALR
>NZ_CP048104|867754:880104|874776_880104_+|WP_173220829.1|DBSCAN-SWA
MGTTETVGTLVDALRENASSMPDHRAYSFLVDGEQDRMDITSAELDARSKAIAAALQGCVANSERALLLFPPGLDFVVSFYGCLYAGVCAVPCYLPSVPRAKSNSMLDRFVTIARDCNASVILTTSELMDKLQERWRKFELDTDILWLATDTIHENRGQDWVEPSISGDTLAYLQYTSGSTSVPKGVMVTHANLINNSRMMQKASQSTAGVEIVSWLPVFHDMGLIGAILQSQLLNGSCTFMTPQHFIKKPIRWLQLISQCKNEHIISGGPNFAYDLCVREISEKDMDSLDLSRWKTAFNGSEPVRRETVDSFIEKFKRCGFQKSAMHPTYGLAETTLMVSGRQQKEPQLFVADAALLEQGKAVKADPRNSRTKTLVGCGCSVEGQELLIVDPDTRQICKTGGVGEIWVSGPHVANGYWNQEAATENAFHAYTATGEGPLLRTGDLGFLNEEELYITGRIKEVIIIRGRNLYPQDVERSAGRSHDSLLAGLAAAFAVEVEGEERLIVVQAVNRRSDADFSEVARKIRENVSEDHDVELYGVVLVKPSEIKRTTSGKIQRSLCRDAFLNESLEVIAQSMLGHDENEREDELSRKYLLDLEPMERRSVLEKHLKKKVADKLKVPSSSFGMDTYLTSLGIGSLSTFDLLGSLERQLDVKLTMGETLNDVVNEVLEQLEATPVSLPKVEEDLENRHQPFPLTDIQYAYFVGRSGAFELGRVSTHAYYEMESENMDLSRLGRAWQGVIRRHEMLRAVIMPSGEQRIMAEDEVPAYEIVETDLRGASPDEVNAYLQSVRDRMSHLVRPTEKWPLFEICATRLDDRVRVHFSFDLIVADVWSFRILLKEWADLYEQLDTILPPLNLSFRDYVLAEKKLESTELYEQSRKYWLSRLSQLPPAPELPMVQASGLEEKQPRFVRRSAYLPSKKWQTLKERGAKNGLTPSHILLAAFSQILAAWSKNQQFTLNVTLFNRLPIHPQFNEIVGDFTSVELLEVDLRNSGRGLEELAKDLQKQLWNDLEHSYFSGIRVLREMTRQHGGVRSVMPVVFTSALGQVIGEADDLPISRLGKVVYGVSQTPQVYLDHQVYEQKGDLAFNWDTIDDLFPAGMLDDMWNAYVGFLEDLAEREELWKERDYQWLPDDQLRQREEVNATQGRVPKDLLQAPFAEQAAMHPDHPALISSEGTLSYEELFRRANQLGRRLREEGVRPGMLVGVAIGKSWEQIVAVLGVLQAGGAYLAVDPDLPEERQVYLLEHGQVDVVLTCDGRPITGGWPEHVQVMAADLKGWEGAEGDPLEPVQSPDDLAYVIYTSGSTGQPKGVMISHRAALNTVLDINDRFEVGPKDAVLALSALHFDLSVYDIFGMLAAGGTIVLPEAEASRNPKRWLDLMQEHDVTIWNSVPALLEMLVEQASGEAVPPSLALRQVLLSGDWIPVYLPDRIKSLIKGVQVVSLGGATEASIWSIFYPIGEVDSKWESIPYGKPLTNQTFAVLNERMEPCPVWVPGQLYIGGLGLAKGYWRDEEKTAAHFIEHPETGERLYRTGDLGRYLPDGNIEFLGREDFQVKVRGHRIELGEIESTLVQHPQVKQAVVAAVGADRNHKQLVGYVVPKIKQKGQNMNQTITEFLSKKLPSYMIPQGYVMLDEIPLTPTGKVDRKALGQLTNWRQTPGTEYEAPRNEIEKTISNTLQRILEVEKIGINDNFFDLGADSVTVTRAYRHLKEDLSRDFSLLSFFEYPSVRLLAAHLSGEANEQSAVQQGSERARKKRAAQVNRRNKKRYRSGG
>NZ_CP048104|867754:880104|868779_869796_+|WP_173220815.1|DBSCAN-SWA
MSTAEPKTEKILEVNQVKKHFDMGRGQVVQAVDDVTFHVYKGETLGLVGESGCGKSTMGRTIIRLYEATDGEIKFKGKNTKNLSGKELHQFNREMQMIFQDPYASLNPRMTVGDIIAEGLDIHGLAKGKERREKVVELLRTVGLNEEHADRFPHEFSGGQRQRIGIARALAVEPDFIIADEPISALDVSIQAQVVNLMKKLQREKGLTYLFIAHDLSMVKYISDRVGVMYLGNLVELADSQELYDHPLHPYTEALLSAVPIPDPDTDERRERIILKGDVPSPIDPPSGCRFRTRCPKAMDICGQEVPKWQEVRPMHWVACHLYQEESMKKENKEKSSH
>NZ_CP048104|867754:880104|873058_873520_-|WP_173220823.1|DBSCAN-SWA
MGSINRFNAHNEHPIHPFRQEMERMMSRFFDSPFFRGDSSLFQPAFNLEEHEDHYHVEAELPGITPEDIQIEVHGNTLTIRGEKHRKKEQEQEGQVHMVESQYGSFRRVITLPSDADMDAITADSDNGLLHITVPKDQKQAPRRIEIQNKKRH
>NZ_CP048104|867754:880104|870592_871519_+|WP_173220819.1|DBSCAN-SWA
MKQVFGNIKELIGNTPIVRVNGFKLPEGVRIFAKLEYLNPGGSVKDRLGMALIQAAEREGKLKPGGTIIEPTAGNTGIGLALAAVGTGYQVIFVVPSRFSEEKQELMRALGAKVVNTPRELGIKGAIAKAKELEQEIEGSYCPQQFANPANPEVHYQTTGPEIWDQMEGRVDVLVAGAGSGGTFMGVARYLKEQNPDVKTVIVEPQGSILGGGEPGPHKTEGIGMEFLPDYMNPAYFDAVHTVLDRDAFKMVRELASREGMLVASSSGAAFYAALQEAESASAGTNIVVLFPDGSDRYLSQNIYQEEV
>NZ_CP048104|867754:880104|869979_870201_-|WP_173220817.1|DBSCAN-SWA
MEEQVEEVLDKLRPFIQRDGGDVELVEVEDGIVRVRLLGACGSCPSSTITLKAGIERALIEEVPGVTEVEQVL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173220813.1|867754_868783_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-18	29.9
WP_173220815.1|868779_869796_+	ATP-binding cassette domain-containing protein	M1IB70	Acanthocystis_turfacea_Chlorella_virus	1.2e-06	22.7
WP_173220817.1|869979_870201_-	NifU family protein	Q58MC7	Prochlorococcus_phage	1.1e-10	47.3
WP_173220819.1|870592_871519_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	3.1e-70	44.6
WP_173225173.1|871528_872656_+	bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase	A0A0B5JD48	Pandoravirus	2.5e-18	28.7
WP_173220821.1|872675_873008_+	DUF1462 family protein	NA	NA	NA	NA
WP_173220823.1|873058_873520_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_173220825.1|873578_874205_-	class D sortase	NA	NA	NA	NA
WP_173220827.1|874556_874724_+	hypothetical protein	NA	NA	NA	NA
WP_173220829.1|874776_880104_+	amino acid adenylation domain-containing protein	A0A2K9L3I8	Tupanvirus	9.1e-66	28.1

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP048104|1493723:1506572|DBSCAN-SWA
GATGAATCCTGGGAAGAGTCGCTTCCAACGCACCGCTTGGGTCCTACTTTTATCCATCTCTCTACTGTTCGCTGTTTGGCCGATAGAAACTATCCATGCTGATAAGGAAGATGAACTGAAAAAAAAGCTGGATGACATCGAAAAGGAAAAAGGCCAGGCGCAAGAAAGCATCAAGGAGCTGGAGTCAAAAGTCGAAGAGCGGAAAAAGAAACTGAGTGAAGTGGAACAAGACTTGCAAGAAACAGAAGACAAAATGGACAAATCAGAAAAGAAGCTGAAAAAAGCACAGGATAATCTGGATCGATACAGCAGTGATTATAAAAACAGTGTTCGCTCCATGTATCTAAACGGAAACTCAGGACAAATGGAATCACTCTTGAATGCTGAATCTTTCGGTCAATTTTTGTCCCGGTTCGAAATCATGCGTTTGATGGTGAAAAGAGACTATAATGTAGTGGAAAAATATTATAAAGAAAAGGAAAAAGTGAAAAAAGAACGGGATAAAATCGCTAAGTTGCAAAAGAAGAAAAAAAAGGAAGTTGAAAAAGCCGGGAAAGCATACCAAGAGTTGGCAGAAGAGATGAATAAGAACAGGGAAGCTCTATCTTCTCTCAGCCAGAAAGAAGTGGATTACCGGAAAGAGCTGAAGCAACTGAACCTGGATAAAATCAAAGTGAGTAACGCTCCCTTCCAGGGTGGAGGGGGAGCTTTGAGCAGGCCTGTAAACGGGAGGATGACTTCCGGTTACGGAATCCGGGGAGGTGGGGAATTCCATACGGGAGTCGACTTTGCCAACTCCATTGGAACCCCCATTTATGCCGCAGGCAGTGGGAAAGTGATCCGGGCACAAACTTGCAGCTGCGGGTACGGGTACTATATCATGATTGATCATGGCGGCGGCATTTACACTTTGTATGCCCACAGCTGGGCGACGCAATCAAGGGTTCGGGTGGGTCAAGTGGTTCAAAAAGGTCAGCAAATTGCTGCCATCGGCAACAACGGGCGATCTAGCGGCCCCCACTTACATTTTGAAGTTCACAAAGGAAGACCCGGTAATTATGTCAACCCTTGGTCTTACATCCGATAATACGCTTGAATACTCTCCTGTTAAACAGGGGAGTATTTTTATGTTTAATCGAATAGTGGAGAAAGGTGTGTAGATATTGTGCCGAATGGCTTAGATAAAAGGGAGGTGGGTTAAAATGTGTTATGATGATACTTGAAAATATACGGGTCGGATAGGAGGAACCTAATCCTATGAATCGCTATCTACGAGGTTTTTCCGTCTTGGGAGTAATCGGGACTTTTATTATACTCTTGCAAGGGGCCTTGGTAACCAAGACTGGTTCCGGGGAAGGGTGCGGAAATACATGGCCTTTTTGTCATGGTGAAGTGATGCCTTCCTATCATACTGTTGAGTTGTGGATTGAGTATAGTCACCGCATTGTTTCCGCTTTGGTCGGTTTAATTGTGGTCATTTTATCCGTATGGGCGTGGAAAACGTATCGGGATCATAAAACGATCAAGTTTCTGGCTTTTAACAGCGTCTTTTTTATTGTTTTACAAGGGGCATTGGGAGCCTCCACGGTCATTTCCAAGCATACAGATGCGGTGTTAGCCTTACATTTTGGCTTTTCCCTACTCTCCTTTGCCAGTGTAGCTCTCCTTGCTGTCTTCTTGTTTCAGTTGGGGAAAACAGGTGATCTCGGTTTCGATTGGCAAACCATTCCCCAAAGGTTTCGGTATGGATTGTATGGATTGGCGATCTATACGTATGTGGTGGTTTACACAGGAGCATATGTGCGCCATGCCGGAGCCAGTTTAGGTTGTAAACAATGGCCTCTTTGCGGGACATCCTGGTTGACGGATCTGACAGGACAAGCAGGAATTCACATGATACACCGCCTTTTTGCCGGACTGCTCTTTGTTTTGACAATCTGGTTGTGGTGGGTTGTCCGAAGACATTATACAGAGCGGAAAGATCTCAACCGAGGAGCTACCTTTGCCTTGGTCATGGTAGTGCTTCAGGTGATTACCGGCGGATTGATTATATGGAGTAACCTGCAACTCATGATTGCGCTTCTCCATACCACTTTGATTGCGGCATATTTCTCGGCATTGTGTTATTTGTGTTTTCAGGTTGGGTTACCCTGGAAATGGTCGAAGAATGAGACCAGCATATCAGGATAGATAAGCAACGGATCTACAACCAAAAAGAGACCTTTTATAAGGTCTCTTTTTGGTTGTAGAAACTGTTTCTCATACAGGTTATAATAAACATGATCCAGGGACCTTTTGCGGAATAGGGTTTCCTTTGGTGTCACTGAATCGATATTAATTGTATAATCTGTCAATCCTTCGGGGCCGGGTGAAAATCCCGACCGGCGGTGATGGTGCTTGACGCCTCAGTCCGTGACCCGCGTGAAGCGGTGGACCCGGTGAAACTCCGGGACCGACAGTGAAAGTCTGGATGGGAGAAGGATGAGCAGGATGATTACACCTGAATGCATGTAAGATGCGATCTTTTTTGGATGAATCCCCCTTTTGACAAGGGGTTATTTCGCATACCCGGAATCATGTCAGAGTCGGGAGAGCATCGGTTCGTCCAAAGCAAGATCGGTACTTTTCTTTGGTGTGTCTTCTTGTCCCGTTCATATGCCCCGTTTACGGGGCTTTTTTTGTTGGTTTGACAGAATGAAATGAAGGGGGTCTGTTTAGGATACGGATCATTGGGTTCAGTAATAAAGAAAGGGTTGATTGGATCGCCGCTATGGAACGTCTGCTTTTGAGGGAAAGAATCTCTATGTATTGCTGCACGATGGGGATTCAAGAGGGAAGGATCGAAAAGTTCCAGAGGATTTGGAGGGGAAAGGATGTTTACCGGATTGGTAGAAGAAGTGGGGCACATTCATTCGCTCCATCGCCAAAGAAACGCGATGCAACTTACAATTTGTTGCAGTCGGGTCCTGGAGGATACAAAAATTGGTGACAGCATTGCAGTCAATGGGGTTTGTTTGACGGTGACGCAAATGGGAAACGATCGCTTTACAGTGGACGTGATGCCGGAAACCATGGAAAAATCCAATCTGGGTCGGCTCTCATCGCGATCTCCCGTAAATCTTGAACGTGCTGTGGCGGCAGGGGAGCGTTTTGGCGGTCACTTTGTTCAAGGACATGTTGACGGGACTGGAGTAGTTCGTTCCTGTTCTCCGTACGAGAACGCAGTTTTGTTTCAAGTGGAAGTTTCGGCTTCCCTGTCCCGGTGGATGATAGAAAAAGGATCGGTAACGGTAAATGGAATCAGCTTGACTTTGATGGATGTGCAAACAAATGGGTTTACGGTATCGGTTATCCCTCACACCCTGGAGCAGACTCAATTGAAGCATACTCAGCCAGGGGACTGTGTCAATATTGAGTGCGATATGATCGGAAAGTATGTAGACCGCTATATGGGGGTCCAGTCCCGGGAATTGACATTGGAAAAGCTAAGTCGTTTCGGTTTTGCGGCAGAAAAGGGGGATATCCGATGAAGTTTGATTCCATTGAAGACGCTGTTCAGGACTTGAAGCAAGGTCGGATAGTAATCGTGGTGGATGATGAAGATCGGGAAAATGAAGGAGATTTCGTGGCATTGGCGGATAAAGCCACGCCAGAGATTATCAATTTTATGATTACCCACGGGCGGGGACTGGTTTGTACACCCATCACGGAAGAGAGAGCGATGGAGTTGGAACTGCCTTTGATGGTTCATCACAATACTGAAACCCATGAAACCGCCTTTACGGTTTCTGTGGACGGCAAAGAGAGTACAACCGGAATTTCTGCCCATGAGAGGGCGGCTACGGTGCAAGCTCTTCTCCGTCCCGACACAAGTCCCCGGGATTTTCGTCGACCTGGACACATATTTCCATTGATCGCCAAAAAGGGGGGTGTACTGCGTCGGGCAGGCCATACGGAGGCGGCTGTGGATTTGGCCCGTTTGTGCGGTGCATATCCGGCTGCGGTAATTTGTGAAGTAATCAAGGAAGACGGTACCATGGCCAGGGTTCCAGACTTAATGGAGACAGCCCGGGAGTTTGATCTGAAGATTATTACCATTCAAGACTTGATTCACTATCGAAGTCGGACAGAACGGTTGGTTGAGCAAGTGGTTTCCACCAAGTTACCTACAGAGTATGGGGACTTCAGGGTTGTCGGGTATCGAAATGACGTGGATGACAAAGAGCATATCGCTTTGGTAAAGGGGGAGATCACGCCGGACAAACCGGTTGTGGTTCGGGTTCACTCTGAATGCCTGACCGGTGATGTTTTCGCTTCCCGTCGTTGTGACTGCGGTCCCCAATTGGATGCGGCTTTAAAGCGAATTCAGCAGGAAGGGACTGGTATTCTTCTGTATATGCGGCAGGAGGGACGGGGGATCGGTTTGTTGAACAAATTAAAGGCATATAAACTGCAAGATGAAGGATTGGATACCGTGGAGGCCAACAAAGAACTCGGTTTTCTCCCTGACTTACGAGAGTACGGAATCGGAGCTCAAATACTGAAGGATCTCGGTGTGGGAAAAATGCGTTTGTTGACCAATAATCCCCGGAAAATCACCGGGCTGAAAGGCTACGGATTGGAAGTGATCCAAGTCCTGCCCCTTCAATTGCCCTCTGTTCCGGAAAATGAATACTACCTCAAGACCAAACAGATTAAGCTGGGGCATCACCTTCATATATAAAAGGAGAGGATTATCTTGTCTAACATATGGGAAGGAAAATTAACGGCTCAAGGGATGCACATTGGAATCGTAGCAGCTCGCTTTAATGCCTTTATTACGGAAAAATTGGTGACAGGAGCCGAAGATGCCCTGCGTCGGCATGGAGTTGACCCGAATCAGATTGATATTGCCTGGGTGCCCGGAGCTTTTGAAATTCCCCTCATTGCTGACCAGATGGCCGGTTCCGGACGTTATGATGCTGTGATTACTTTGGGAGCAGTCATCCGTGGAGCCACTCCCCATTTTGATTACGTATGCAGTGAAGCCGCCAAAGGCATATCCGCCACAAACCTGAAATACAGTGTGCCGGTTATTTTCGGACTGTTAACAGTGGATACGATTGAACAAGCCGTGGAGCGTGCAGGTACCAAAGCTGGAAACAAAGGATGGGACGCCGCAGTTGCCGGGATTGAAATGGCCAACTTGCAACAGACGCTCAAACAAAAGTTGCAGAAGTGACAGACGGGAGGGACTGATAGTTTGGATGTCAAAATCAAACTGGAGATGTTTGAAGGACCTTTGGATCTCCTTCTTCATCTAATTGATCGATCCGAATTGGATGTATGTGATATCCCTATCGCAAAAATTACGGATCAATATATGGAGTATCTTTCGACCATGCAGGAATGGGAGCTGGATATTTCCAGCGAGTTTTTGGTGATGGCGGCGAACTTACTGGCCATTAAGAGTCGAATGCTGTTACCCAGGGCGGAGCCGGCAGACTTGACGGATATGCTGATGGATGAAGAAGAGGGAATGGATCCCAGGGAAGAGCTGATACAACGGCTCTTGGAATATAAAAAGTACAAACGTCTTTCTGATGTACTCCAATCCAGGGAGGAAGAAAGGAGTCAGGTTTACACCCGAATGCCGATGGATTTGTCTCCCTATGCACCAGAGGAAAATCCGGTGGCAGGCTTAACACCGGATGACTTGCTTCAGGCTTTTGCTGAAGCTCTGACTCGGCAGAAAGAGACGGAAGAACCCATGACACAAATGACCCGGGATGAAGTCTCCGTAAGTGATCGCATGGAGGAGATAGCCCGTACCCTATCGGACTCCGGAGGGTTGCTTCACTTTTCGAAGCTGCTCCATTGGAATCGGGTTACAAAGGAGAGAATTGTAACGACCTTTTTGGCTTTGTTGGAACTGATGAAAACCAAACGCATTAAAATTATGCAGGGCGGGTTATTTGAAGATATCCGCATTGAACTGAAACCGGAGGGAGGCAGCCCTGGTGGAACGGGAGCAGTGGAAACCGGTTATTGAGGGGTTGTTGTTTGCCGCAGGGGAAGATGGATTACGTTTGACAGAGATGATGGAAGTGACCGGGTTGTATAAGCCGGTGCTGACCCAGTTGATTGAAGAGATGAGACGGGAGTGGAAGGAACAGGGGCGGGGGGTGCAAATTGTGGAAGTCGCCCAGGTTTATCAACTGACCACGTTGCCGGAACATCGGCCATATTTTGAAAAGCTGGCTCAATCCCCCACTCGTTCACGGTTATCCCGTGCTGCTTTGGAAACCTTGGCGATTATTGCTTACCGGCAACCGATTATCCGGGTGGATGTGGAAGAGGTCCGAGGGGTTAAATGCGACAAGGCGATCTATTATTTAAAACGAAAGGGTTTGATCCGTGAAGTGGGAAGGGCTGAAGGTGCCGGTCGGCCCATCCTCTATGGAACAAGTCGGGACTTCCTGAATTACTTTGGGTTGAAAAGTTTGGATGAGCTTCCGCCAGTGGACTCCATCTTCGATTGGGCGGAGATGGAACAGGAACGGGAAGAATTATACCGGCGCTTGGGAGTGGAGCCACAGAGTGAGGATGTGGCAAATGATGAAGATGAAGTGGAGCCGGATTCTCAAAAAGTGGAAATCGATCTAATTTCCGAGGCTTAAATGGATTGAATCATCAAAAAGTGGGCCATCCGCACAGAATATGCGTGCTGGCCCACTTTTTGATGATTCGATAGAATGAATCATGATGGTGGAATCAATGGACATCCGCTTTTTCGATATTTCGAATCGACCAAAAAGCTATGATGACTCCGATTACAGCAAGAGATACTGGAATATAAATAATAGAAGCCAAGGAGAATAGTGGGTTGTGTGCGCTGGTAAGGGCTATGATCAGAATTGATGATAGGATGGTAGCCGGTACAGAATGTTTACGCATCCCAAAATACAAAGGAATTATGCTTGTTCCCGCAGTCGCAAGTGCAAATGCCAACATATTTAAAAACTGTTGAAAAAAAGTGTGGTTCGTCGTCGACAACGGAATAAAATCCAAATAGGAATTTACGCTAAATACCACACTCGTTACAAAGATGTTGGAAACAATCGTCATTATGAATGTCAGCCCACTGATAATCAATAATTTGGCAGCGATCAGTTTTTTTCGGTTAACCGGGTAGGTAAACATAACGAAAATGGTTTTGTTTTTATATTCTTCAACGACTAATTTAGCAATTAATACAGCGGCAAAAACCGTAAACGTAGCCCTGACTATCGCGCCAATTATGATGAAAGCTTCTTGAGTATCCTGAAAAGGAATATTTCCTTCCACTTTTTCTATATAACCGATTAAGAAGATTAAACAAGCAATCAAAGGATTTGCCAAGAGGGTTGCTTTCCAATACCAACCGAATTTATTTTTCTTCGCTTCCAATCTTATTAGTCTCAGCATACAGACAACACTCCGTTTGCATATTTAAGAATGGATCTTGTCATCGTGAATGAGACCCAGGAAATATTCCTCCAGGGACATCGCCTTTCTGTTCATTGACTCGATCCCAACATCATGTAAAATCAATGTCTTGGAGATCACTTCCTGTGATATCTTTGATTCATAAATCCGAATTGTTTTTTCATCGATCACTTTAAAGTTGGATATATGAAGTTTATCAACAATCACAAAGCAGGCTTTCCTCTGATTTGTTGTTGTTATCTCGATGTATTGGGTGGTTTGACCTCTGATACTGTCCATGGGGATTTCTGTAATGAGCCTGCCATCACGGATCACCCCAATTACGTCTGCGAGCTGTTCAATTTCTGCTAAAATATGACTGGAAATTAACAATGTCGTCCCGTATTCTTTGTTCAATGTATGAAATACATCTCGGATTTCTTTAACTCCAACAGGATCCAGACCGTTTATCGGTTCATCTAAAATTAGTAACTCAGGTTTTGTCATAATGGCTCTGGCAATGCCTAAACGTTGCTTCATTCCCAGTGAAAAGTTTTTCACAGGCTTGTGGTCAATATTTTTTAGATTCACCATAGCCAATGCTTCACTAATAGCCTCACGATTGTAGTAGCCCATATACTCACAGTGAAGCTCTAAATTCTCCCAGGCTGTCATTTTCTCGTAAAAAATTGGATATTCGATCATACTCCCGATTCTGCCCAGAATATCATAGGATGAATGTGTTAACTTTTGACCCAATATTTCAATTTCCCCTGCTGAGGGCTTAACAAGATTCGTAAGCATTTTCATCACTGTTGTTTTACCGGCGCCATTTGGGCCAAGGAAGCCATAAATTTTTCCTTTGGGAACGTTCATGTTCATATTTGATATGACTTCTTTGCCTTGGAACAATTTTGTTAACTGGTTTGTCCTTACGAGATACGTCATAGGTGATCCCTCCTTTTCGATATAACTCTCTTTTATTTTAGGGGTGAACCCTTTCTTTATTATTTCGTAATTCTTAAGAAGATCTTACACTGTCAGTCTGAAATTCGTTTCAATTGGATCGTAAAAGTTGTTCGATGATAGGGTGTGCTCTGTAAAGAAATCTTCCCTCTCAGCTTTTCAACAAGCCTTTTTGTAATGGTTAACCCCAGACCACTTCCCTGAAAGAACTTGTTTCTGGACTCCTCAAGTGTGTACAATCTTTCAAATATATGTTCCTGCTCCCGCTCATTGATTCCTTTTCCCCGGTCCCACACATCAATGAAGAGTTGTTTATCGTTATATCTCAAGGACAAGCCAATTACCTTTCCATCACCGCCATAACGAATCGCGTTGGATAACAAATTGGTTAATATACGGTCCAGAGCCTCTTCATTACCCAACGCATAAATAGGATGGTCAGGGATTTGTATAACCATTTCAATCCCTTTTCCTTGAATCCAATCATAGAATAATAGGAGATTCCTTTTGCAAACTTCATTTATATGCACCTTGGTTAAAGGAATCTCTTTGTCACCTGATTCCAATTTTGCTAAATCAAAAAAAGAGTTCATTAGCTTGATGATTTCTGATGTCTTTTCGTGAATATTGAGTAGTATTTTCTCTTTCTCTTTTTGAACAATCCCTGGATCATGTTGAATGGTTTCAATATAGCCCAAAACAACGGTTAACGGTGTTTTTAAATCATGGGAGATATTGGACAGCATTTTTTTAATGGAGCGTTCCGTTCTTGTGAATTGGGCCTCGATGCGCTGACTATAGTCCATCAACTGATTGATTTCCACTAATAAAGCCCGCAGGTATGGATCGTCAGTGGCAAGTAAAAGCTGTTCGGAAGAGCTTTCTTCTGTGATCTGGTGTAGCTTTTTCGATAAATAGGCAAGCTGTGCATCCCTTTGCTTTTTGATCCGAAACTGAATCGTATTTAGGATGGTTAATCCAATAATCAAGCAGGTCAGTATAAGGGTCATCTTAAAATTCTCCAAGTCTGTAGCCGATTCCCCACAGGGTTTTAATATATTGGGGATGCGATGGATGATCTTCTATTTTTTCTCTCAATCGTCTTATATGTACGTTAATAATGTTGGCATCACCGTAGTAGGCATCGTTCCAAACCAAGTGATAAATCTGTTCTTTTGTAAAAGTCCGTTTGGGATTTGTGAAAAGTAGCTTTAATATTTTCCATTCTGTTGAAGTAAGTTTTATCTCCTTGTCCTTCTTACGGATGATGAAGTTTTCAGTATCCATGGTAATTTCGTGGACACAAATTATACTCTCCTTATTTTCACCATCGGAATACTGTGTGGCTCTTCTGATTGCCGCCTTCACTCTTGCGGTTAGTTCGATCATTGAAAAGGGTTTAACGAGATAATCATCTGCACCGAAGCCCAAGCCCAAGGCCTTTTCCGCATCGCTGTCTTTAGCAGATAGAATCATTACCGGAACCACGCTCTGTTCACGGACCATCTTTAAGAAATCTATTCCATTCAGTTTGGGTAACATTAAGTCCAGAAGTATCAAATCAAAGGAATCCCGACGGAACATTTGCATGGCTTCCATTCCATCAAATACACGAACAACATGAAAACACTCTTTTGTCAAAAAATCCCCAACCATTTTACTGATTGACGGATCATCTTCTACCAGCAGTATCTTTTTTTGCAACTTTTGTCACCGCCTCTATCTCATTCATTTCACTATATACCTTGCTGTGTCATTACCTCCAGCCCATGTTGAGCCGGTTGGGGGGGAGAGTATGACTGTTGCCTTTGAGTCCTCTTGATCTTGGAGGAGTAAAGACCCAAGGAATCCAAAAACAAAAAAAGGCTATGAATGTTATTTTAGCAAATATACAAGAAAGAGAACTCTCATGGACCCGGTTGATTTTTACCTGATTGAAAGGAATGCCGAGGATAAATTTTGGGAATGAATCATAGCAGAGAGTCTTGGTATTCTGGATGGTTTACATACCTGATACTGGAAAGTGTAGGGGATTGGCATGGGCTGGCTGTTTTTGGTGGCTGGTATTGGGGTTATGGGCGTATTTGTTTTGTCTCCGGTACGAGTGTTCGTGGTGTATTATCGACGGGGTGAAGATGATCAATTAAAAACACAGATTCGTCTGTTGTGGGGACTGATTCGCCTTCGTTATGAGATGTCCATGGCAGACTTGACTGAGAAAGGTCTTCAGGTAAAAGAAAAAGGAGTTCCAAAATCACCGGGTAAGAAAAAAAGACGGCGAAAACGAATCACCTTGGCCACCCTTCAAAGATGGGCACGGGAAAGCCGGTATCTGCAGGAGCGAATTGTTCATCTGTATGATGTTTTACGGCGATTTTTCAGTCAAGTGGTTTGTGAACGCTTAACCTGGGTTTCAGATATTGGAACTGGGGATGCAGCTGAAACAGGAGTGTTGACCGGAGTGGTTTGGTCTGTTAAAACCACAATGATTGGTATGCTGGGTTCTTATATTCGGTGGGGCCGCTCCCCAGACTTGGATGTTCGCCCCTTTTTTGAGAAAGAAATATTGGATACGAATCTGAACTGTATAATCCGCTTTCGAGTCGGGCATGCTATCCTCGCTGTCTTACGTCTGCTGACAAGGATTCATGGCAAAGGGAGTGAAAAGAATTGGCAGAGCACCCTATACAAGGCTTGATGACCACTGCGATGGAAAACATCAAGGAAATGGTGGATGTCAATACGATTGTGGGTGACCCGGTGGAAACACCCGACGGAAAGATCATTATTCCTGTTTCCAAGGTGGGATTTGGCTTTGCCGCCGGTGGGAGTCAATTTACCGGCCAGTCCAATAAAGAGGGTGGTACCGGTGGTACTGGCAAAGCACAGGATCAGAACAAACCTTCCGAACTCCCTTTTGGAGGAGGGAGTGGTGCAGGTGTCTCCATTACCCCGATCGGCTTTCTGATTGTGGGAGAAAATGGGGTACGCATGCTGAATGTAGAAGGATCTCAGCATTTGTATGATCGCCTGTTGGATCTGGCACCCGGCTTGGCAGAGCGTCTGCAAAATTTGATGAAGCCTAAAAATGAACAGTGTAAAGACCCGAAGACAGACCTGTGATCACGGATTCGGTCATAACCGGAAATGAGGTTTCAGTAAGAACAGCCATTTCGAATAAATACAAATGGGACCCGGATGTAGTTTTTTTAGACACCGTTTCGAGAGAGGAACGGTGTTTTTCATTATTTCATAAACTTGTCCGTTAAGCATATAAATGAATAAAAAGCCCTAAGGTGGAGAAGCAATGCGGCGGATGACTCTTTTAATCATTTTGATTTTTACAGTGGTTCAGTCGGCTGGGAAGGTACAGGCTCAGGAGAATCCCCCGGAACTGAGTGCACGAACAGCGGCTTTAATCGATGTTGAATCAGGTCGCCTCTTGTATGAGAAAAAAGCGGAGAAACAGATGCGGATCGCCAGTTTAACCAAAATCATGACAGCCATTGTCGCCATTGAAAACGGGAGTCTGAAGCAATTGGTGACAGTGGGTCCCAATGCAGTGGGAGTAGAAGGGTCCTCCATCTATTTAAAGCAAGGGGAGAAGATCCCCCTGGAATCCTTGTTGTACGGGCTGATGCTCCGATCAGGCAATGATGCAGCTGTGGCCATTGCTGAACATATCGGGGGAAGTGTAGAGGGATTTGTATTCAAAATGAACGAAAAGGCTGAATTTATCGGTTTAAATGGGACCCATTTTCAAAATCCCAGTGGCCTGGATTCTCCCGGACATTATTCCACGGCACAGGATATGGCTAAACTGACTGCATATGCTCTTCGGAATCAAACATTCCAAAAGATTGTTTCCACTCCGGTTAAAACAGTTCCCTGGCCGGGGGAAAAGTGGCATCGAAAATGGTATAACAAAAATAAAATACTGCGGTTATATTCCGGCGCAAACGGTGTAAAAACCGGATATACCAAACTCTCCAAACGAACCTTGGTTGCTTCAGCTTCACGAAACGGCAGGCAATTGGCTACCGTAACATTAAATGCTTCCGATGATTGGAATGATTCCATGCTTTTATTGGAGTATGGATTTAGGCACTTTCAAAAAGTAAAGTTGATCAACCGGGGAAAGGTTTTTCCTACTCAGCCGGATCGTAAGGGGAAGTTTAAAGTTGTGGCCCGGTCCGATTTTATCTATCCCTTGAAACCAGAAGAGAGGAAAAAGGTACAGATAAAACCCATCATGATGGTTCCCTTAAAAAAAGTGGACCGGGAAGGTTTGAAGGTGGGAAAAGCCTGGATTTATCTGGATGAACAGCCCGTTGGGTCGGTTGATTTAATTACGGAAATGATGGCGGAAAAGGCGGAAAAAACGGCATTTTCGGATTGGTGGAGGATTTTTGCTCAAGTGGTGGGGAGAGAGGGGTAG

Protein sequences of DBSCAN-SWA_3

>NZ_CP048104|1493723:1506572|1496595_1497252_+|WP_173221818.1|DBSCAN-SWA
MFTGLVEEVGHIHSLHRQRNAMQLTICCSRVLEDTKIGDSIAVNGVCLTVTQMGNDRFTVDVMPETMEKSNLGRLSSRSPVNLERAVAAGERFGGHFVQGHVDGTGVVRSCSPYENAVLFQVEVSASLSRWMIEKGSVTVNGISLTLMDVQTNGFTVSVIPHTLEQTQLKHTQPGDCVNIECDMIGKYVDRYMGVQSRELTLEKLSRFGFAAEKGDIR
>NZ_CP048104|1493723:1506572|1494979_1495912_+|WP_173221816.1|DBSCAN-SWA
MNRYLRGFSVLGVIGTFIILLQGALVTKTGSGEGCGNTWPFCHGEVMPSYHTVELWIEYSHRIVSALVGLIVVILSVWAWKTYRDHKTIKFLAFNSVFFIVLQGALGASTVISKHTDAVLALHFGFSLLSFASVALLAVFLFQLGKTGDLGFDWQTIPQRFRYGLYGLAIYTYVVVYTGAYVRHAGASLGCKQWPLCGTSWLTDLTGQAGIHMIHRLFAGLLFVLTIWLWWVVRRHYTERKDLNRGATFALVMVVLQVITGGLIIWSNLQLMIALLHTTLIAAYFSALCYLCFQVGLPWKWSKNETSISG
>NZ_CP048104|1493723:1506572|1504804_1505257_+|WP_173221836.1|DBSCAN-SWA
MAEHPIQGLMTTAMENIKEMVDVNTIVGDPVETPDGKIIIPVSKVGFGFAAGGSQFTGQSNKEGGTGGTGKAQDQNKPSELPFGGGSGAGVSITPIGFLIVGENGVRMLNVEGSQHLYDRLLDLAPGLAERLQNLMKPKNEQCKDPKTDL
>NZ_CP048104|1493723:1506572|1493723_1494809_+|WP_173221814.1|DBSCAN-SWA
MNPGKSRFQRTAWVLLLSISLLFAVWPIETIHADKEDELKKKLDDIEKEKGQAQESIKELESKVEERKKKLSEVEQDLQETEDKMDKSEKKLKKAQDNLDRYSSDYKNSVRSMYLNGNSGQMESLLNAESFGQFLSRFEIMRLMVKRDYNVVEKYYKEKEKVKKERDKIAKLQKKKKKEVEKAGKAYQELAEEMNKNREALSSLSQKEVDYRKELKQLNLDKIKVSNAPFQGGGGALSRPVNGRMTSGYGIRGGGEFHTGVDFANSIGTPIYAAGSGKVIRAQTCSCGYGYYIMIDHGGGIYTLYAHSWATQSRVRVGQVVQKGQQIAAIGNNGRSSGPHLHFEVHKGRPGNYVNPWSYIR
>NZ_CP048104|1493723:1506572|1499721_1500381_+|WP_173221826.1|DBSCAN-SWA
MEREQWKPVIEGLLFAAGEDGLRLTEMMEVTGLYKPVLTQLIEEMRREWKEQGRGVQIVEVAQVYQLTTLPEHRPYFEKLAQSPTRSRLSRAALETLAIIAYRQPIIRVDVEEVRGVKCDKAIYYLKRKGLIREVGRAEGAGRPILYGTSRDFLNYFGLKSLDELPPVDSIFDWAEMEQEREELYRRLGVEPQSEDVANDEDEVEPDSQKVEIDLISEA
>NZ_CP048104|1493723:1506572|1500475_1501168_-|WP_173221828.1|DBSCAN-SWA
MLRLIRLEAKKNKFGWYWKATLLANPLIACLIFLIGYIEKVEGNIPFQDTQEAFIIIGAIVRATFTVFAAVLIAKLVVEEYKNKTIFVMFTYPVNRKKLIAAKLLIISGLTFIMTIVSNIFVTSVVFSVNSYLDFIPLSTTNHTFFQQFLNMLAFALATAGTSIIPLYFGMRKHSVPATILSSILIIALTSAHNPLFSLASIIYIPVSLAVIGVIIAFWSIRNIEKADVH
>NZ_CP048104|1493723:1506572|1497248_1498445_+|WP_173221820.1|DBSCAN-SWA
MKFDSIEDAVQDLKQGRIVIVVDDEDRENEGDFVALADKATPEIINFMITHGRGLVCTPITEERAMELELPLMVHHNTETHETAFTVSVDGKESTTGISAHERAATVQALLRPDTSPRDFRRPGHIFPLIAKKGGVLRRAGHTEAAVDLARLCGAYPAAVICEVIKEDGTMARVPDLMETAREFDLKIITIQDLIHYRSRTERLVEQVVSTKLPTEYGDFRVVGYRNDVDDKEHIALVKGEITPDKPVVVRVHSECLTGDVFASRRCDCGPQLDAALKRIQQEGTGILLYMRQEGRGIGLLNKLKAYKLQDEGLDTVEANKELGFLPDLREYGIGAQILKDLGVGKMRLLTNNPRKITGLKGYGLEVIQVLPLQLPSVPENEYYLKTKQIKLGHHLHI
>NZ_CP048104|1493723:1506572|1504172_1504832_+|WP_173221834.1|DBSCAN-SWA
MGWLFLVAGIGVMGVFVLSPVRVFVVYYRRGEDDQLKTQIRLLWGLIRLRYEMSMADLTEKGLQVKEKGVPKSPGKKKRRRKRITLATLQRWARESRYLQERIVHLYDVLRRFFSQVVCERLTWVSDIGTGDAAETGVLTGVVWSVKTTMIGMLGSYIRWGRSPDLDVRPFFEKEILDTNLNCIIRFRVGHAILAVLRLLTRIHGKGSEKNWQSTLYKA
>NZ_CP048104|1493723:1506572|1498964_1499753_+|WP_173221824.1|DBSCAN-SWA
MDVKIKLEMFEGPLDLLLHLIDRSELDVCDIPIAKITDQYMEYLSTMQEWELDISSEFLVMAANLLAIKSRMLLPRAEPADLTDMLMDEEEGMDPREELIQRLLEYKKYKRLSDVLQSREEERSQVYTRMPMDLSPYAPEENPVAGLTPDDLLQAFAEALTRQKETEEPMTQMTRDEVSVSDRMEEIARTLSDSGGLLHFSKLLHWNRVTKERIVTTFLALLELMKTKRIKIMQGGLFEDIRIELKPEGGSPGGTGAVETGY
>NZ_CP048104|1493723:1506572|1503145_1503823_-|WP_173225357.1|DBSCAN-SWA
MLVEDDPSISKMVGDFLTKECFHVVRVFDGMEAMQMFRRDSFDLILLDLMLPKLNGIDFLKMVREQSVVPVMILSAKDSDAEKALGLGFGADDYLVKPFSMIELTARVKAAIRRATQYSDGENKESIICVHEITMDTENFIIRKKDKEIKLTSTEWKILKLLFTNPKRTFTKEQIYHLVWNDAYYGDANIINVHIRRLREKIEDHPSHPQYIKTLWGIGYRLGEF
>NZ_CP048104|1493723:1506572|1498460_1498943_+|WP_173221822.1|DBSCAN-SWA
MSNIWEGKLTAQGMHIGIVAARFNAFITEKLVTGAEDALRRHGVDPNQIDIAWVPGAFEIPLIADQMAGSGRYDAVITLGAVIRGATPHFDYVCSEAAKGISATNLKYSVPVIFGLLTVDTIEQAVERAGTKAGNKGWDAAVAGIEMANLQQTLKQKLQK
>NZ_CP048104|1493723:1506572|1501192_1502116_-|WP_173221830.1|DBSCAN-SWA
MTYLVRTNQLTKLFQGKEVISNMNMNVPKGKIYGFLGPNGAGKTTVMKMLTNLVKPSAGEIEILGQKLTHSSYDILGRIGSMIEYPIFYEKMTAWENLELHCEYMGYYNREAISEALAMVNLKNIDHKPVKNFSLGMKQRLGIARAIMTKPELLILDEPINGLDPVGVKEIRDVFHTLNKEYGTTLLISSHILAEIEQLADVIGVIRDGRLITEIPMDSIRGQTTQYIEITTTNQRKACFVIVDKLHISNFKVIDEKTIRIYESKISQEVISKTLILHDVGIESMNRKAMSLEEYFLGLIHDDKIHS
>NZ_CP048104|1493723:1506572|1502208_1503144_-|WP_173221832.1|DBSCAN-SWA
MTLILTCLIIGLTILNTIQFRIKKQRDAQLAYLSKKLHQITEESSSEQLLLATDDPYLRALLVEINQLMDYSQRIEAQFTRTERSIKKMLSNISHDLKTPLTVVLGYIETIQHDPGIVQKEKEKILLNIHEKTSEIIKLMNSFFDLAKLESGDKEIPLTKVHINEVCKRNLLLFYDWIQGKGIEMVIQIPDHPIYALGNEEALDRILTNLLSNAIRYGGDGKVIGLSLRYNDKQLFIDVWDRGKGINEREQEHIFERLYTLEESRNKFFQGSGLGLTITKRLVEKLRGKISLQSTPYHRTTFTIQLKRISD
>NZ_CP048104|1493723:1506572|1505441_1506572_+|WP_173221838.1|DBSCAN-SWA
MRRMTLLIILIFTVVQSAGKVQAQENPPELSARTAALIDVESGRLLYEKKAEKQMRIASLTKIMTAIVAIENGSLKQLVTVGPNAVGVEGSSIYLKQGEKIPLESLLYGLMLRSGNDAAVAIAEHIGGSVEGFVFKMNEKAEFIGLNGTHFQNPSGLDSPGHYSTAQDMAKLTAYALRNQTFQKIVSTPVKTVPWPGEKWHRKWYNKNKILRLYSGANGVKTGYTKLSKRTLVASASRNGRQLATVTLNASDDWNDSMLLLEYGFRHFQKVKLINRGKVFPTQPDRKGKFKVVARSDFIYPLKPEERKKVQIKPIMMVPLKKVDREGLKVGKAWIYLDEQPVGSVDLITEMMAEKAEKTAFSDWWRIFAQVVGREG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173221814.1|1493723_1494809_+	peptidoglycan DD-metalloendopeptidase family protein	D7RWE0	Brochothrix_phage	2.7e-17	41.3
WP_173221816.1|1494979_1495912_+	heme A synthase	NA	NA	NA	NA
WP_173221818.1|1496595_1497252_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.0e-39	39.5
WP_173221820.1|1497248_1498445_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.8e-107	49.5
WP_173221822.1|1498460_1498943_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.1e-39	53.6
WP_173221824.1|1498964_1499753_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.7e-08	25.6
WP_173221826.1|1499721_1500381_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.4e-16	31.8
WP_173221828.1|1500475_1501168_-	ABC transporter permease	NA	NA	NA	NA
WP_173221830.1|1501192_1502116_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-42	44.0
WP_173221832.1|1502208_1503144_-	sensor histidine kinase	W8CYF6	Bacillus_phage	1.1e-22	24.0
WP_173225357.1|1503145_1503823_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.2e-32	34.2
WP_173221834.1|1504172_1504832_+	DUF2953 domain-containing protein	NA	NA	NA	NA
WP_173221836.1|1504804_1505257_+	sporulation protein YtfJ	NA	NA	NA	NA
WP_173221838.1|1505441_1506572_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.9e-26	32.0