CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP054010	Prevotella melaninogenica strain FDAARGOS_760 chromosome 1, complete sequence	9 crisprs	cas1,cas9,cas3,PrimPol,DEDDh	1	18	2	0
NZ_CP054011	Prevotella melaninogenica strain FDAARGOS_760 chromosome 2, complete sequence	8 crisprs	DEDDh,csa3,RT,WYL	0	0	4	1

1. NZ_CP054010

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP054010_1

• CRISPR_ID: NZ_CP054010_1
• CRISPR_location: 9440-11486
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 26 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NZ_CP054010_1

Consensus_repeat	Method
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CRISPRCasFinder
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	PILER-CR

spacers of NZ_CP054010_1

>1.1|9487|30|NZ_CP054010|CRISPRCasFinder
ACCTTCTTCATACTCCCTCGCATATTCATT
>1.2|9564|29|NZ_CP054010|CRISPRCasFinder,PILER-CR
ATAGTATTAATTAAAATTATAGTCAAATG
>1.3|9640|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
AAACACAGAAGAATCACGAATACCAGCAGG
>1.4|9717|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
CATTTGAGGCAGGGGAATCAACGTTAGCAG
>1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TAAGCGTTATTATCCGCTGCAACGCGAGCC
>1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TGATAAAGAGAAAATAAACAATCAATATAA
>1.7|9948|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TAAGAAGCAACTACCAAAGTACACGTACCC
>1.8|10025|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TGGAGCAAGCGACAGAGTACCACGCAGGGT
>1.9|10102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
CATTTGAAGCAGGAGAATCAATATTAGCGG
>1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
AAAAATAGCACAATAATAGACTATAAAACG
>1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTGCTTCCTCAGCTGATTTAATAGCATTTG
>1.12|10333|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTTAAGATGTTACGCTTATACTTCAATTTA
>1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
AACAGAACGCAGGCAGCACCACAACAAGCA
>1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTGTTTCGTAAAGATGGTCTTCCCACTTTT
>1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TGGATAGTATGTATATTCTCTTTCTCGGCA
>1.16|10641|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTGCAATCTCTACACCGTACTTCTTTTCAT
>1.17|10718|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
GAGTGCAGAGATATAGACCTGTCTTAGGGC
>1.18|10795|29|NZ_CP054010|CRISPRCasFinder,PILER-CR
TACCTTGAGATATTCATAGATACGTCCAC
>1.19|10871|29|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTGCTCAACAGGCAAGTTAACAATAGCGT
>1.20|10947|31|NZ_CP054010|CRISPRCasFinder,PILER-CR
TAACTTGGTTGAATTGCTCAACAGGCAAGTA
>1.21|11025|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TAACTTGGTTGAATTGCTCAACAGGCAAGT
>1.22|11102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
GAAAGTAGCTGAAGCACGGTTAGCAGAAGT
>1.23|11179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TAGGGCAATTAAGAAAGCAACTCTTAATAA
>1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
TTATGTTAAATCAATAGACGAAATGAAATG
>1.25|11333|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
CTAACGATGATTGCCTACACCCTTACTGGT
>1.26|11410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR
CTGAGCACCAGCTAAAGGCTGCGAAATGGG

CRISPR arrays and Neighbor proteins around NZ_CP054010_1

CRISPR arrays

The CRISPR arrays of NZ_CP054010_1

>merge|NZ_CP054010|1|9440-11486|CRISPRCasFinder,PILER-CR
GTATTATGTGTGTAAACAATGTGTATCTTTGTGGTATCTAAAACAACACCTTCTTCATACTCCCTCGCATATTCATTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACATAGTATTAATTAAAATTATAGTCAAATGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACAAACACAGAAGAATCACGAATACCAGCAGGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACCATTTGAGGCAGGGGAATCAACGTTAGCAGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTAAGCGTTATTATCCGCTGCAACGCGAGCCGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTGATAAAGAGAAAATAAACAATCAATATAAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTAAGAAGCAACTACCAAAGTACACGTACCCGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTGGAGCAAGCGACAGAGTACCACGCAGGGTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACCATTTGAAGCAGGAGAATCAATATTAGCGGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACAAAAATAGCACAATAATAGACTATAAAACGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTGCTTCCTCAGCTGATTTAATAGCATTTGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTTAAGATGTTACGCTTATACTTCAATTTAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACAACAGAACGCAGGCAGCACCACAACAAGCAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTGTTTCGTAAAGATGGTCTTCCCACTTTTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTGGATAGTATGTATATTCTCTTTCTCGGCAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTGCAATCTCTACACCGTACTTCTTTTCATGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACGAGTGCAGAGATATAGACCTGTCTTAGGGCGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTACCTTGAGATATTCATAGATACGTCCACGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTGCTCAACAGGCAAGTTAACAATAGCGTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTAACTTGGTTGAATTGCTCAACAGGCAAGTAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTAACTTGGTTGAATTGCTCAACAGGCAAGTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACGAAAGTAGCTGAAGCACGGTTAGCAGAAGTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTAGGGCAATTAAGAAAGCAACTCTTAATAAGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACTTATGTTAAATCAATAGACGAAATGAAATGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACCTAACGATGATTGCCTACACCCTTACTGGTGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAACCTGAGCACCAGCTAAAGGCTGCGAAATGGGGTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC

>NZ_CP054010|1|1|9440-11486|CRISPRCasFinder
GTATTATGTGTGTAAACAATGTGTATCTTTGTGGTATCTAAAACAAC	ACCTTCTTCATACTCCCTCGCATATTCATT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	ATAGTATTAATTAAAATTATAGTCAAATG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AAACACAGAAGAATCACGAATACCAGCAGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CATTTGAGGCAGGGGAATCAACGTTAGCAG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAAGCGTTATTATCCGCTGCAACGCGAGCC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGATAAAGAGAAAATAAACAATCAATATAA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAAGAAGCAACTACCAAAGTACACGTACCC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGGAGCAAGCGACAGAGTACCACGCAGGGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CATTTGAAGCAGGAGAATCAATATTAGCGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AAAAATAGCACAATAATAGACTATAAAACG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCTTCCTCAGCTGATTTAATAGCATTTG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTTAAGATGTTACGCTTATACTTCAATTTA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AACAGAACGCAGGCAGCACCACAACAAGCA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGTTTCGTAAAGATGGTCTTCCCACTTTT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGGATAGTATGTATATTCTCTTTCTCGGCA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCAATCTCTACACCGTACTTCTTTTCAT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	GAGTGCAGAGATATAGACCTGTCTTAGGGC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TACCTTGAGATATTCATAGATACGTCCAC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCTCAACAGGCAAGTTAACAATAGCGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAACTTGGTTGAATTGCTCAACAGGCAAGTA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAACTTGGTTGAATTGCTCAACAGGCAAGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	GAAAGTAGCTGAAGCACGGTTAGCAGAAGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAGGGCAATTAAGAAAGCAACTCTTAATAA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTATGTTAAATCAATAGACGAAATGAAATG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CTAACGATGATTGCCTACACCCTTACTGGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CTGAGCACCAGCTAAAGGCTGCGAAATGGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC

>NZ_CP054010|1|1|9517-11486|PILER-CR
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	ATAGTATTAATTAAAATTATAGTCAAATG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AAACACAGAAGAATCACGAATACCAGCAGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CATTTGAGGCAGGGGAATCAACGTTAGCAG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAAGCGTTATTATCCGCTGCAACGCGAGCC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGATAAAGAGAAAATAAACAATCAATATAA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAAGAAGCAACTACCAAAGTACACGTACCC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGGAGCAAGCGACAGAGTACCACGCAGGGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CATTTGAAGCAGGAGAATCAATATTAGCGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AAAAATAGCACAATAATAGACTATAAAACG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCTTCCTCAGCTGATTTAATAGCATTTG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTTAAGATGTTACGCTTATACTTCAATTTA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	AACAGAACGCAGGCAGCACCACAACAAGCA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGTTTCGTAAAGATGGTCTTCCCACTTTT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TGGATAGTATGTATATTCTCTTTCTCGGCA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCAATCTCTACACCGTACTTCTTTTCAT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	GAGTGCAGAGATATAGACCTGTCTTAGGGC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TACCTTGAGATATTCATAGATACGTCCAC
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTGCTCAACAGGCAAGTTAACAATAGCGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAACTTGGTTGAATTGCTCAACAGGCAAGTA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAACTTGGTTGAATTGCTCAACAGGCAAGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	GAAAGTAGCTGAAGCACGGTTAGCAGAAGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TAGGGCAATTAAGAAAGCAACTCTTAATAA
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	TTATGTTAAATCAATAGACGAAATGAAATG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CTAACGATGATTGCCTACACCCTTACTGGT
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC	CTGAGCACCAGCTAAAGGCTGCGAAATGGG
GTTGTGATTTGCTTGAAAATCTGTACCTTTGTGGTATCTAAAACAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_004359992.1|26609_27149_-|carbonic-anhydrase	unknown	unknown	gnl|CDD|239474
NZ_CP054010.1|WP_004359997.1|20085_20703_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_172891268.1|6042_7923_-|IS1634-family-transposase	unknown	unknown	gnl|CDD|227708
NZ_CP054010.1|WP_004359994.1|23980_24346_+|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367747
NZ_CP054010.1|WP_004359996.1|20889_23121_-|glycoside-hydrolase-family-92-protein	unknown	unknown	gnl|CDD|377950
NZ_CP054010.1|WP_004360002.1|8554_9142_-|YkgB-family-protein	unknown	unknown	gnl|CDD|225601
NZ_CP054010.1|WP_004359995.1|23239_23671_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004360239.1|2829_5856_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NZ_CP054010.1|WP_004360000.1|12025_12958_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NZ_CP054010.1|WP_004360001.1|11676_12018_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NZ_CP054010.1|WP_004360240.1|1873_2665_-|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239491
NZ_CP054010.1|WP_004359993.1|24404_25643_+|M56-family-metallopeptidase	unknown	unknown	gnl|CDD|320700
NZ_CP054010.1|WP_004360241.1|560_1721_-|ATPase	unknown	unknown	gnl|CDD|369347
NZ_CP054010.1|WP_036886125.1|12969_17454_-|CRISPR-associated-protein-Csn1	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|375967
NZ_CP054010.1|WP_004359998.1|17763_19182_-|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377164

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP054010.1|WP_004360001.1|11676_12018_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	4.5e-34	111.9	0.1
NZ_CP054010.1|WP_036886125.1|12969_17454_-|CRISPR-associated-protein-Csn1	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	1.7e-63	210.0	46.5
NZ_CP054010.1|WP_004360000.1|12025_12958_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	2.3e-84	277.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_004359992.1|26609_27149_-|carbonic-anhydrase	gnl|CDD|239474	cd03379, beta_CA_cladeD, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	1.8853e-54
NZ_CP054010.1|WP_172891268.1|6042_7923_-|IS1634-family-transposase	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.70693e-11
NZ_CP054010.1|WP_004359994.1|23980_24346_+|BlaI/MecI/CopY-family-transcriptional-regulator	gnl|CDD|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	9.07876e-32
NZ_CP054010.1|WP_004359996.1|20889_23121_-|glycoside-hydrolase-family-92-protein	gnl|CDD|377950	pfam07971, Glyco_hydro_92, Glycosyl hydrolase family 92. Members of this family are alpha-1,2-mannosidases, enzymes which remove alpha-1,2-linked mannose residues from Man(9)(GlcNAc)(2) by hydrolysis. They are critical for the maturation of N-linked oligosaccharides and ER-associated degradation.	0
NZ_CP054010.1|WP_004360002.1|8554_9142_-|YkgB-family-protein	gnl|CDD|225601	COG3059, COG3059, Predicted membrane protein [Function unknown].	1.15944e-60
NZ_CP054010.1|WP_004360239.1|2829_5856_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	7.30195e-05
NZ_CP054010.1|WP_004360000.1|12025_12958_-|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.44387e-115
NZ_CP054010.1|WP_004360001.1|11676_12018_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.73108e-29
NZ_CP054010.1|WP_004360240.1|1873_2665_-|phosphatase-PAP2-family-protein	gnl|CDD|239491	cd03397, PAP2_acid_phosphatase, PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.	1.63396e-94
NZ_CP054010.1|WP_004359993.1|24404_25643_+|M56-family-metallopeptidase	gnl|CDD|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	1.16988e-25
NZ_CP054010.1|WP_004360241.1|560_1721_-|ATPase	gnl|CDD|369347	pfam07396, Porin_O_P, Phosphate-selective porin O and P. This family represents a conserved region approximately 400 residues long within the bacterial phosphate-selective porins O and P. These are anion-specific porins, the binding site of which has a higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates, while porin P has a higher affinity for orthophosphate. In P. aeruginosa, porin O was found to be expressed only under phosphate-starvation conditions during the stationary growth phase.	1.26973e-18
NZ_CP054010.1|WP_036886125.1|12969_17454_-|CRISPR-associated-protein-Csn1	gnl|CDD|375967	pfam18541, RuvC_III, RuvC endonuclease subdomain 3. Cas9 proteins are abundant across the bacterial kingdom, but vary widely in both sequence and size. All known Cas9 enzymes contain an HNH domain that cleaves the DNA strand complementary to the guide RNA sequence (target strand), and a RuvC nuclease domain required for cleaving the noncomplementary strand (non-target strand), yielding double-strand DNA breaks (DSBs). The crystal structures of type II-A and II-C Cas9 proteins highlight the features in Cas9 enzymes that support their function as RNA-guided endonucleases. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. The RuvC domain forms the structural core of the nuclease lobe, a six-stranded beta sheet surrounded by four alpha helices, with all three conserved subdomains (I, II, III) contributing catalytic residues to the active site.	7.83178e-51
NZ_CP054010.1|WP_004359998.1|17763_19182_-|PepSY-domain-containing-protein	gnl|CDD|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.56671e-06

Protein sequences

>NZ_CP054010.1|WP_004360002.1|8554_9142_-|YkgB-family-protein
MNKVKLLLDFVLNTAASLKGTGIHLIRIAIFIIFVWIGGLKFWNYEAEGIVPFVANSPFMSFFYAKDAPEYKDYKLKEGEFDKVKHEWHEANNTYTFSHGLGIAIMSFGILTLLGIWFPKVGFVGSGLVIIMTFGTLSFLVTTPEVWVPDLGSGEHGFPLLTGAGRLVIKDVCILAGAVVVLADCAQRILKNNKR
>NZ_CP054010.1|WP_172891268.1|6042_7923_-|IS1634-family-transposase
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKTRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYSGVPGWTPGINSLYKITDKLYELKEQLERHLCSVTDDIFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINQEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVVMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDEDYYLEITSPSKAMTESSMNRVWKERFEMELQRINDGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKILKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNDLNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGETIEMRQCSSPSKQAKQIYDKLNLKHLPFKKNKICRTQSP
>NZ_CP054010.1|WP_004360239.1|2829_5856_-|hypothetical-protein
MSTLSIDKKGYWIGGETGVIWHVNGQDRKRFYTGLDRIYDIERDPNQSDQIWIASRNAGLQLWNIAADTLVHKVTFEIPSKGSRYSPYNIDIADGTLFVATSQGLFSMPLNQQQQGLKPLYPIHKEKTGQYYEPFLVNNLCHVGNKWLFAATQAGIISINLQTKKTELRHKGENIRSVAIYDGKLYILSDNQLTIEGFNGANSKTFSLPQSVLSFYKASSTYYFITSSSILLSDNLKRFVTIPLRNNIPDNPHQISIADDGNGFSVLLTKNAVWCIPHHLGFFNANPPVVTACLSDKSLIYVNNQHELFCQKSGEQIATKIYDFENDELPKEMYANGEDIYYYNANNQLFRLNLGNHYLINQLFKRPQLLAQTKTRITSMAFLPRQSKILLGVQDYLLSIDTQNGKTDTIKAMDNRYITAFHQVKNGEGIYIATLNHGVFFGKHGQIKQVAGTHDKVFINGLLTYGEQNPHLLLLTNHHLQIQGSDSIQTDGSCRMFCINDSVVYTIPETGIHKYIIKKGRLIDCGSYFADIHFNAQAGVILDNTLYIGSDLGVLQLIPGKEEVAKWITFDNKVPSLQLIGIILFTLICILGIIFISYRRHQILTYRQLQMSKDDLHQRLEALESLKDKLTEVERNTLNSINNEIDSINISSQSLRNNNEHFAKLSARIARLNRDTALQMVKYLNDQIARIKQFEVYERDTMVHESEEARNTDNIEVIIEQCRRNEVWLNHIQELKERLNKFHRSTQDTLVLKGLNDGMKERLHHILNESKQHPVAEVYSDFIAVKHQYENIFTQDGLKIIRNYISDSIKQLKEFEGYEIMTKALSDELQSIENDIDNRDRIVLLRLLQTIDNRINQIKHLKTLQKLMQDYTAVHENVVQENEERRMKKFNSKLFADIDSATRDITDQIAEVSDEFFKSFAMTDKEVCKEIFHFTAANSQQVRVLILLLAMPRVKRTLLPGMLGIYGNLNPVVSRLYHSKIGDNKVILTAYYNENPASIVYYILKLSE
>NZ_CP054010.1|WP_004360240.1|1873_2665_-|phosphatase-PAP2-family-protein
MTKKTLVVGLLAMFSVTTFAQTAAKKIKDVRTQPDLYYLQDGQQASSLELLPAPPQPGSIQFLYDEAQYQWGKMQRNTPRGDQAAADARVGGDGVPNAFSEAFGIKISKETTPEIYKLVLNMREDAGDLATRSAKDHYMRVRPFAFYNEMTCNPEQQQELSTNGSYPSGHTAIGWATALVLSEINVDRQNEILERGYQMGQSRVICGYHWQSDVDAARVISAAVVARLHAEPAFQEQLAKAKKEFAKLKKEGKIAKSTFKTAN
>NZ_CP054010.1|WP_004360241.1|560_1721_-|ATPase
MKRIILIATCALMTCASAFAQEEAEPKLVVKPTGRILMDAGVMHSTDETLDNQLNDGVAIPDVRMGVSATYGKWKAKVDVGYARQSLSLKDISLDYNFNKENLIRMGYFVHQFGLQSGTSSSFKISMEEPLANQAFFNSRLIGAMYVHAGEKFHATASVFAENDAMKMTTDKLGNEAWGAMTRLVWRPLTERGKIFHIGISGAYESPRYNKDATISHKSYTLKAPFPTRIANVAAQEAKISDAKALWKFSPEMNFAIGNFGFEAQYFYVGIKRDNAMPNYNAWGAYSNVRYLLNGQGYTYTKADAGIATPDPGSLELVAAYNYSTLTDKDANVFGGKVNDWSLTFNYYLNKYMIWRVRGSITRATDNAAFNNNTFSILETRLQIKF
>NZ_CP054010.1|WP_004360001.1|11676_12018_-|CRISPR-associated-endonuclease-Cas2
MTGFERFSEYRIMWILVFFDLPTETKKEKKAYSDFRKSLIKDGFTMFQFSIYVRHCASMENAEVHIKRVRTMLPKLGKVGILCITDKQFANIQLYYGEKEQTPNAPGQQLELF
>NZ_CP054010.1|WP_004360000.1|12025_12958_-|type-II-CRISPR-associated-endonuclease-Cas1
MIKKTLCFSNPIYLSLRNAQLVLHLPEVESNKTLPEAIKKEAERTIPIEDIGVVILDNRRITITSGVMEALLENNCAVITCNQKSMPVGLLLPLCGNTTQNERFRSQLEASLPLRKQLWQQTIKQKILNQEYVLRTNTDKETNCMRVWSNDVRSGDPENLEARAAAYYWKNLFINYPNFVRDREGTPPNNLLNYGYAILRAIIARALVGSGLLPTLGIHHHNRYNAYCLADDIMEPYRPYVDQLVLDIIQCNSEISDITRDLKMQLLGIPMLDVVINGKRSPLMIAAQQTTASLARCFAGESKRISYPEM
>NZ_CP054010.1|WP_036886125.1|12969_17454_-|CRISPR-associated-protein-Csn1
MKTILGLDLGTNSIGWAKVCVNDNGNYTREIKLGSRIIPMSQDTLSNFDKGVTESPTAARTGFRGIRRIRERALQRRERLHRVLHVMGFLPLHYENAIGWNREEATTYGKFLDNGEPKLAWERQEDGSMRFLFMDSFYEMMADFAKYQPGMVADGRKIPLDWTLYYLRKKALTQAIRKEELAWILLNFNQKRGYYQLRGEEEEENSTKHEEYYELKVVSVEAAEEGKGGNTWYNVTLENGWIYRRQSKIELNDWVGKVRPFIVTTEYEIDGVTIKKDKNGEVKRSFRAPSENDWGLRKKRTESLLEESGKTVGAFIYNHILSEPADKIRGNFIRTIERKFYKKELEAILREQSKHQKELKDIDTLIACIKELYPNNKPHQDSLIKKDMTYLLITDLIFYQRPLKSKKSLIADCPYEYYEYVIKETGENKRQSIKCIAKSNPYYQEFRLWQFIINLRLFDRNNDKEVTSEYLSSMEDYTRLFTYLNDRKDINQETLLKDFFKQKKVKRGMEKEFPIRWNYIEDKEKKYPCNETRHELLTALGKVGIDHSWLDDKELFYRLWHLLYSVESKEEAEGALRKLVDNDDFVNAFLKIKPFKKEYGAYSEKAIKKLLAVMRMGNLWNEVDICEQTRDRIQNIIKGDIDEKIKDRMGRTFSQLSDFQGLPEWLACYVVYGQHSEATDIQRWTKPENLMAYINGFKQHSLRNPIVEQCILETLRTVHDIWKEAGHIDEIHIELGRGMKSTADQRARMSKSIMQNENTNLRIKSLLMELKNAKEFENVRPYSPMQQEILRIYEEGALQELTKEDAQYNEISKISQMAQPSANELLKYRLWLEQKYCSPYTGKPISLSKLFTSAYQIEHIIPQSRYFDDSFTNKVICEAEVNQLKSNMLGYEFIKKHGGEIVRCTMIGDVKLLDAKEYYNFVTEHYTNNRRKKEKLLMEDIPQEFLNRQMNDSRYISKKVMAILSNIVREEDEQEAKSKFVIACSGGITDRLKQDWGLNDVWNSIVYPRFERLNKLTNTENFGRWENKKGKQVFQTSVPLELQKDFSKKRIDHRHHAMDALVIACASNNIINYLNNESAKSQEKREDLRKKLCDKNRIIRKPWETFTQDAHTALENVVVSFKNYIRVINKATNYYEKYDKNGKKEIAEQKGQDMWAIRKPMHKETVFGQVNLRRKITIKLKDALEKIPAICDKELRDYINILVAKQFNKKQILAHFKSINYRLNMKSVDKVDVWQFSNEKEPMVATRKSVDTSFDTKRIATITDTGIQKILLNYLKAKNNDPNIAFTPEGIAEMNKHITEYNNGKQHQPILKVRVSEPKGAKYQVGETGNKRSKFVEAQKGTNLYFAIYEDKEGNRSYNTIPLNEVIERLKQGLSPVPDANEKSIPLKFHLSPNDLVYVPKTDEENEIKMGQIYKFVDSSGTTANFVPHRVSNLIYNVDKKIAENFCNHEIIQNEYGIGSPQSKNQKSITGEMIKAVCWKLEVDRLGNIHKIIK
>NZ_CP054010.1|WP_004359998.1|17763_19182_-|PepSY-domain-containing-protein
MKRKTWRKYHKWIGIIITFFLVMFCLSGIVLNHRQLFSDINVSRGILPGQYEFNQWNNGLLRGTLRYKDNKNKDKVFIYGAAGVIQTDTTASHFTEYNQGLPAGADYRQMRGMAKTPQNDLFAVSVMDLYKLRKNASWQKIDLPKEENDELLTDITTHGDTLIVLSRSHLYYATAPYKKFTCLTLQAGEGNEGKVSLFRQIWLLHSGALFGTVGKLIVDGIGIVLIILCLTGIWYWIRHKATSMVVWHTKIGHYTFALTLFIAITGWALRPPLMILLATNNTKPLPGTTLDNDNPWNDKLRMIRYDEQAHDWLISTSEGFYSLKNLSSKPTPITTAPPVSVMGQNVWQHADNKSWIVGSFDGLFYWDRKNNVVLYYNDAMVSTPRIPGTAPDEQTISGYSSDFTNKECIATYFQGSSFATQPEELKDKPMSLWSLALEVHTGRIYAGALGSFLFIFVIGILIIFTLVSGKKA
>NZ_CP054010.1|WP_004359997.1|20085_20703_-|hypothetical-protein
MKKNFFSNHALCAGLVLGGLFTFSSSHAANNEVKDNNNVVAAAPTTNSKIVGTWELTNKGSYAIVRNPRTHKEYKVGFTIDRYDDYKFLPVDFATGEPVNLRTLVGHDDNDLDDELHRFDFYHDGTMSIIEREDNGRWKRDDDIGVYGFHRDGFFMKIDGKMRKNLQIRFLNNNEFELTQTKFNDSDLRRVVVKKVMRYVRVTRK
>NZ_CP054010.1|WP_004359996.1|20889_23121_-|glycoside-hydrolase-family-92-protein
MKRSLFLVFLLLTFIAHLYAITVNNPVDYVSTLVGSASKPELSTGNTYPAIALPWGMNFWTPQTGKMGDGWTYTYGADKIRGIKQTHQPSPWINDYGQFSVMPVVGNKVFDEEGRASWFSHKAETAAPYYYKVYLADHDVTVEVSPTSRAATMRITYPQTKEAYFVVDAFDKGSSVTIIPDKRTIVGYTTKNSGGVPANFKNYFVLRFDHDFSFVGSIEDGKLSEGKTSTTSNHAMAVVGFHTKRGEQVNIQVASSFISDEQAQRNLKEVEGKTFDEVKSEGRKEWNNILGRIEVEDDNIDHLRTFYSCLYRSVLFPRSFYEFDEQGNPIHYSPYNGKVLSGYLFTDTGFWDTFRSLFPLLNLVYPSMNEKMQAGLVNAYKESGFLPEWASPGHRDCMVGNNSASVVADAYIKGLRGYDIETLWEAVVHGANAVHPTVSSTGRKGFDYYNRLGYVPYNVGINESVARTLEYAYDDWCIYQLGLKLGKSAKELKPFKLRAMNYQKVFDKETGLMRGRNEDGSFQSPFNPFKWGDAFTEGNSWHYTWSVFHDPAGLAKLMGGYDKFNEILDSVFQLPPTFDHSYYGFTIHEIREMQIMNMGNYAHGNQPIQHMIYLYDYSGQPWKAQYWVREVMDRLYTAQPDGYCGDEDNGQTSAWYVFSALGFYPVCPGSTQYMIGTPYFRKVKIQLENSKTVTIRAEKNNKDNRFIQHITVNGQPYPHYYLEYEQLLSGPIIDFTMGDKPAK
>NZ_CP054010.1|WP_004359995.1|23239_23671_-|hypothetical-protein
MIRKLYTFLAVAALMLSSCKKGSQDKPKADSHDIKTIPTEITDNGDQAVKNANKRDAGFISNRVNEVTLTIPCLGVVNMDNLDLLPPPNEISKKDSTIIKQLNNGEVFLLQPGTKGIMLTDAGSKLLVRFQMGELWVWKSATK
>NZ_CP054010.1|WP_004359994.1|23980_24346_+|BlaI/MecI/CopY-family-transcriptional-regulator
MEKLTKQEEEIMLQVWSLKSCTIKDVLQKLEDPKPPYTTVASIMNNLKRKGYVIAEQHGLTYHFVPRIEQTRYKSDFMKGFVDKYFKSSFREMVSFFAKEDNISPEELKDIINEIEKGKEV
>NZ_CP054010.1|WP_004359993.1|24404_25643_+|M56-family-metallopeptidase
MIMYLLKLNIALILLFSFYKLMFTGDTFFSWRRATLIGMYLVAMLVPVMDFSVWLSNSEGMTSIANEYATVVLPAVSTSSQGGEVLLWELIVLIVYSVVACVLLLRFLCQLVSIILLKNNSQSSYICDTEVYLLTDDEGPFSFFDWIFINPERHKSDEIEEIMMHELTHCQQLHSIDIIFSELFCIIFWFNPFVWLLKREVRLNLEYLADNSVLANGKDNKEYQYHLLGLTYRKNVATISNNFNVLPIKKRIKMMNKKETKGFLKAKYALYIPLVAMLLAVSNIETIARNVTKLTTSVELQKKPTKESERVFIVTEVMPTFKGNLYQWLSKNLRYPKDAVSRKEQGRVMVQFVITAKGEVIKPEIVRSVSPSLDKEALRVVSKMPAWNPGRNGNKKVATKYTLPVKFSLGSK
>NZ_CP054010.1|WP_004359992.1|26609_27149_-|carbonic-anhydrase
MIDQILSYNKRFVAAKGYAPFITSSQPDMKLAIVSCMDTRLTKLLPNALGLRNGDAKIIKVAGGTILTPYDSVMRSLLVAIYELGCQEVMIIHHSGCGACNMNADHFLHLMRERGITDEAIKEAEQQVNLNEYLDGFHDTEASVHRTVRTVQQHPLVPKDIIVRGFIIDSRTGELTPVD

Crispr_ID: NZ_CP054010_2

• CRISPR_ID: NZ_CP054010_2
• CRISPR_location: 506582-506681
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_2

Consensus_repeat	Method
TAAACGAGTTAATACTATCAAGCAACTTGT	CRISPRCasFinder

spacers of NZ_CP054010_2

>2.1|506612|40|NZ_CP054010|CRISPRCasFinder
CTACTTGTTGACTTATTGACTTGTCTACTTGTTTGACAAA

CRISPR arrays and Neighbor proteins around NZ_CP054010_2

CRISPR arrays

The CRISPR arrays of NZ_CP054010_2

>merge|NZ_CP054010|2|506582-506681|CRISPRCasFinder
TAAACGAGTTAATACTATCAAGCAACTTGTCTACTTGTTGACTTATTGACTTGTCTACTTGTTTGACAAATAAACGAGTTAATACTATCAAACAACTTGT

>NZ_CP054010|2|2|506582-506681|CRISPRCasFinder
TAAACGAGTTAATACTATCAAGCAACTTGT	CTACTTGTTGACTTATTGACTTGTCTACTTGTTTGACAAA
TAAACGAGTTAATACTATCAAACAACTTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_004359643.1|519901_521503_+|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359640.1|513459_514185_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|187608
NZ_CP054010.1|WP_004359634.1|503645_504155_+|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|214628
NZ_CP054010.1|WP_004359627.1|496978_497512_-|HDIG-domain-containing-protein	unknown	unknown	gnl|CDD|237176
NZ_CP054010.1|WP_036885981.1|506716_508876_-|S9-family-peptidase	unknown	unknown	gnl|CDD|224423
NZ_CP054010.1|WP_004359632.1|502531_503077_+|biopolymer-transporter-ExbD	unknown	unknown	gnl|CDD|376792
NZ_CP054010.1|WP_172891284.1|515724_517605_+|IS1634-family-transposase	unknown	unknown	gnl|CDD|227708
NZ_CP054010.1|WP_036885983.1|521518_524275_+|S8-family-serine-peptidase	unknown	unknown	gnl|CDD|173811
NZ_CP054010.1|WP_004359642.1|518245_519865_+|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359629.1|499521_500337_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_036885979.1|504797_506420_-|MFS-transporter	unknown	unknown	gnl|CDD|340898
NZ_CP054010.1|WP_004359637.1|508878_510810_-|membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|234942
NZ_CP054010.1|WP_004359633.1|503073_503550_+|biopolymer-transporter-ExbD	unknown	unknown	gnl|CDD|376792
NZ_CP054010.1|WP_004359631.1|502019_502535_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_036866321.1|510810_512421_-|CTP-synthase	unknown	unknown	gnl|CDD|235437
NZ_CP054010.1|WP_004359630.1|501077_501911_+|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl|CDD|376576
NZ_CP054010.1|WP_004359628.1|497601_499380_-|biotin/lipoyl-binding-protein	unknown	unknown	gnl|CDD|227349
NZ_CP054010.1|WP_004359641.1|514392_515205_+|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377164
NZ_CP054010.1|WP_004359626.1|495953_496844_-|RluA-family-pseudouridine-synthase	unknown	unknown	gnl|CDD|223638
NZ_CP054010.1|WP_036886031.1|513217_513463_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_004359643.1|519901_521503_+|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	4.72894e-15
NZ_CP054010.1|WP_004359640.1|513459_514185_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|187608	cd05350, SDR_c6, classical (c) SDR, subgroup 6. These proteins are members of the classical SDR family, with a canonical active site tetrad and a fairly well conserved typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	5.47611e-48
NZ_CP054010.1|WP_004359634.1|503645_504155_+|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	9.91732e-39
NZ_CP054010.1|WP_004359627.1|496978_497512_-|HDIG-domain-containing-protein	gnl|CDD|237176	PRK12703, PRK12703, tRNA 2'-O-methylase; Reviewed.	1.15605e-22
NZ_CP054010.1|WP_036885981.1|506716_508876_-|S9-family-peptidase	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	7.58555e-78
NZ_CP054010.1|WP_004359632.1|502531_503077_+|biopolymer-transporter-ExbD	gnl|CDD|376792	pfam02472, ExbD, Biopolymer transport protein ExbD/TolR. This group of proteins are membrane bound transport proteins essential for ferric ion uptake in bacteria. The Pfam family consists of ExbD, and TolR which are involved in TonB-dependent transport of various receptor bound substrates including colicins.	4.94902e-17
NZ_CP054010.1|WP_036885983.1|521518_524275_+|S8-family-serine-peptidase	gnl|CDD|173811	cd07485, Peptidases_S8_Fervidolysin_like, Peptidase S8 family domain in Fervidolysin. Fervidolysin found in Fervidobacterium pennivorans is an extracellular subtilisin-like keratinase. It is contains a signal peptide, a propeptide, and a catalytic region. The tertiary structure of fervidolysin is similar to that of subtilisin. It contains a Asp/His/Ser catalytic triad and is a member of the peptidase S8 (subtilisin and kexin) family. The catalytic triad is similar to that found in trypsin-like proteases, but it does not share their three-dimensional structure and are not homologous to trypsin. Serine acts as a nucleophile, aspartate as an electrophile, and histidine as a base. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of subtilisin. The serine residue here is the nucleophilic equivalent of the serine residue in the S8 family, while glutamic acid has the same role here as the histidine base. However, the aspartic acid residue that acts as an electrophile is quite different. In S53, it follows glutamic acid, while in S8 it precedes histidine. The stability of these enzymes may be enhanced by calcium; some members have been shown to bind up to 4 ions via binding sites with different affinity. There is a great diversity in the characteristics of their members: some contain disulfide bonds, some are intracellular while others are extracellular, some function at extreme temperatures, and others at high or low pH values.	1.36872e-83
NZ_CP054010.1|WP_172891284.1|515724_517605_+|IS1634-family-transposase	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.49204e-11
NZ_CP054010.1|WP_036885979.1|504797_506420_-|MFS-transporter	gnl|CDD|340898	cd17340, MFS_MFSD1, Major facilitator superfamily domain-containing protein 1. Human major facilitator superfamily domain-containing protein 1 (MFSD1) is also called smooth muscle cell-associated protein 4 (SMAP-4). The function of MFSD1 is still unknown. Its expression is affected by altered nutrient intake. During starvation, expression of MFSD1 is downregulated in anterior brain sections in mice while it is upregulated in the brainstem. In mice raised on high-fat diet, MFSD1 is specifically downregulated in brainstem and hypothalamus. MFSD1 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.65127e-22
NZ_CP054010.1|WP_004359637.1|508878_510810_-|membrane-protein-insertase-YidC	gnl|CDD|234942	PRK01318, PRK01318, membrane protein insertase; Provisional.	5.27405e-101
NZ_CP054010.1|WP_004359633.1|503073_503550_+|biopolymer-transporter-ExbD	gnl|CDD|376792	pfam02472, ExbD, Biopolymer transport protein ExbD/TolR. This group of proteins are membrane bound transport proteins essential for ferric ion uptake in bacteria. The Pfam family consists of ExbD, and TolR which are involved in TonB-dependent transport of various receptor bound substrates including colicins.	8.04174e-07
NZ_CP054010.1|WP_036866321.1|510810_512421_-|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_CP054010.1|WP_004359630.1|501077_501911_+|MotA/TolQ/ExbB-proton-channel-family-protein	gnl|CDD|376576	pfam01618, MotA_ExbB, MotA/TolQ/ExbB proton channel family. This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.	1.20556e-27
NZ_CP054010.1|WP_004359628.1|497601_499380_-|biotin/lipoyl-binding-protein	gnl|CDD|227349	COG5016, COG5016, Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion].	1.06086e-69
NZ_CP054010.1|WP_004359642.1|518245_519865_+|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	7.30344e-12
NZ_CP054010.1|WP_004359626.1|495953_496844_-|RluA-family-pseudouridine-synthase	gnl|CDD|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	7.47865e-63
NZ_CP054010.1|WP_004359641.1|514392_515205_+|PepSY-domain-containing-protein	gnl|CDD|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	2.24373e-34

Protein sequences

>NZ_CP054010.1|WP_036885979.1|504797_506420_-|MFS-transporter
MTDKIQTSLRDSAAMRWTALLLLSLAMFCAYIFVDILSPIKELMQEQRGWDSTAFGTMQGSETFLNVFVFFLIFAGIILDKMGVRFTAILSGAVMLAGALIKYYAISDSFAGSALDVWFTNNLNHIPVFEQLGVSPFYQGMPASAKVAACGFMIFGCGVEMAGITVSRGIVKWFKGREMALAMGSEMALARLGVATCMIFSPFFAKLGGDINVSRSVAFGVVLICIALMMFIVYFFMDKKLDSQTGEAEEKDDPFKISDLGKILSSMGFWLVALLCVLYYSAIFPFQKYAVNMLQCNLTFHELPAGSFWASSSVTIIQYVIMLVVAATAFMFNFMKNKALKNFMLFLSVLSLVVYCYMGYMRQSAESIFAVFPLLAVGITPILGSYVDHKGKAASMLVLGSLLLIVCHLTFAFVLPQFKSSQVGGVIVAYVTILVLGASFSLVPASLWPSVPKLVDAKIIGSAYALIFWIQNIGLWLFPLLIGKVLDKTNVGVTDPTQLNYTAPLVMLAGLGVIALIIGLTLKVVDKKRNLGLEEPNIKE
>NZ_CP054010.1|WP_004359634.1|503645_504155_+|Lrp/AsnC-family-transcriptional-regulator
MAHRSLDRLDKKILHLISEDARIPFLEVARACNVSGAAIHQRIQKLTNLGVLKGSQFIIDPERIGYETCAFIGLNLKNPEKFDDVVEALRQIPEIVECHYTTGEYDLFLKIYAYNNHHLMSVIHDKLMPLGLSRSESSISYNAVIDRTLPIEGMKVADVVLDDDEEDEE
>NZ_CP054010.1|WP_004359633.1|503073_503550_+|biopolymer-transporter-ExbD
MKLYRGRNHEIPALNTASMPDLIFSILFFFMLVVHMRKANVHVKYQVPMATELSRMYNNSTIQHIYIGRPINSLGQVEGEKMVVQLNDHITTIPEIKKYLIQLSAALPPEQRKELSVSIKADRHADMGTIMDLKQVLREANVLNVNFTATMSRNNKLK
>NZ_CP054010.1|WP_004359632.1|502531_503077_+|biopolymer-transporter-ExbD
MMFRKRERRKVPILNTTSTADISFMLLIFFLVASSMDLDKGLSRQLPAIDKTKTPPAAVDSRKVMRIVIDAENQVTLDGKVVTMKELLQRATQLIQTNGKGHLIQLQSSRNASYDTYIHVQNQLVAAYNTLRNQRALNLFGKEFELCSNEQQKQIADEVPMRISEVYTVSKADNTEKGGTE
>NZ_CP054010.1|WP_004359631.1|502019_502535_+|hypothetical-protein
MMKIKGIAKMDEERISQRVLYVIVALSAIVFLAFYLIGYDTPFTGNTAFNAPMLTDVLLWFMWGLLAITTIASIVAVVRGIRRANRSEGMTNGIPARKITYTTYGITALILLLTFVFGSTQTMMVNGENFTDSFWLRITDMFVNSSLLLLVLAAGVVAFGATRYYRKGRGK
>NZ_CP054010.1|WP_004359630.1|501077_501911_+|MotA/TolQ/ExbB-proton-channel-family-protein
MKKLIALFSIITILSFSCSTIVSAQAPAKAATTATADTLSDDALNETGVADTATVKTPTAQDTGIHQSLKRKFIEGNAGFMSLVALALVLGLAFCIERIIYLSLSEIDAKRFVGKLDDMIVAGEIEQAKALSRDTRGPVASICYQGLLRIDDSIENIERSVTSYGSVQSANLEKGCSWITLFIAMAPSLGFLGTVIGMVMAFDQIQEAGDISPTIVASGMKVALITTIFGIIVALVLQIFYNYILSKIDHITAQMEESAITLLDAIMKYKLKRIQNS
>NZ_CP054010.1|WP_004359629.1|499521_500337_+|hypothetical-protein
MKKKFFPLFGFALLFLTACYNQVSTGDYSAIDVEVQMKGDSTRYGLACDGCSDSIIVLLPNEGGDPVKFDIVTAKRNGMVYGTPEIGDELAIVPNPIDPFEAEMVINLEQMKGTWTFQVLPKLKPNPTKTEEEILAGMSDSMKAALFTPREYGFTLKSYNQASPVGYIMKANSLEDESPVEYPKVTVYTSWHIFNGRLYIYKDTLDEQGHRIPQDSVGFDSGSMRYLSEDSMAALFGKKVMQYHRKKNALEANKEAQKAEEKNAITQSFKK
>NZ_CP054010.1|WP_004359628.1|497601_499380_-|biotin/lipoyl-binding-protein
MGKKIEFSLIYRDMWQSSGKFQPRKDELVRIAPVFVEMGCFARVETNGGAFEQVNLLAGENPNESVRAYTKILHEAGIKTHMLDRGLNALRMYPVPDDVRALMYRVKHAQGVDITRLFDGLNDIRNIAPALKWAKEAGMTPQGTLCITTSPVHTIEYYCKLADEEIAAGAEELCLKDMAGIGQPAFLGELTRRIKEKHPDIILEYHGHSGPGLSMASMLEVAKNGIDILDVAIEPLSWGKVHPDVISVQSMLKNAGFDVPEINMDAYMKARAMTQEFIDEWLGYFINPQNKIMSSLLLSCGLPGGMMGSMMADLGGIRSTINNLRKKKGEPELSVDDMLVKLFDEVAYVWPRVGYPPLVTPFSQYTKNIALMNLLTLEQGKGRFVMMDDSMWGMILGKSGRVPGEICQELKDLAKQKGLEFTDADPHTLLPNALDDFRKEMDENGWDYGQDDEELFELAMHPEQYRNYKSGQAKKNFLADLQAAKDAKLGAKVSPEEAAAFKHAKADAIVSPVKGQLFWEFQGDGEAAPTIEPFIGKEYKEGDVFCYVQAPWGEFVTVPAALGGKLVEINAKQGAKVDKGDVIAYIERAHEE
>NZ_CP054010.1|WP_004359627.1|496978_497512_-|HDIG-domain-containing-protein
MDYQVIINKYYPEDNELRHILLVHSRAVADKALAIADCHPELSLDRQFIEEAAMLHDIGIVRCNASGIQCFGTEPYICHGRIGAEMLRAEGFPRHARVCERHTGAGITRSQIIAQKLPLPQQDFLPETMEEKVICYADKFFSKSHLDEEKTIEQAIASLSKFGEEGVVRFREWVKMF
>NZ_CP054010.1|WP_004359626.1|495953_496844_-|RluA-family-pseudouridine-synthase
MIRKNPYTEEKYKHYKVTAPAPLLEWLLANLNESKSKVKATLQNRGIKVNGKCVTQFDHPLKAGDKISVSKSKKNDLFRSRYVKIVYEDRFLVVIEKNIGILSMAAGHSSLNVKTVLDDYFRKTKQKCTAHVVHRLDRDTSGLMIYAKDIQTEQLLEHDWHNIVYDRRYVAVVSGEMEHDEGTIANWLKDNKSYVTYSSPVDNGGKYAVTHFHVLDRTVAHSLVEYQLETGRKNQIRVHSADMGHPVCGDIKYGNGDDPLHRLCLHAYVLCFHHPVTHQRMEFETPIPAVFRHLFK
>NZ_CP054010.1|WP_036885981.1|506716_508876_-|S9-family-peptidase
MNKNLTMAMTAALMMSGSVAQAQDVNIGRNNITLTSDLMTPETLWAMGRIGAAQASPDGKKVVYQVGYYSVKENKGHQVLRVMDADGKNDRLLTTSAKSEGDAAWLDNNTLAFLTGGQLWTMNVDGTNRKQLTHSDIDIEGFRFSPDCKRVVLIKSIPYYGTIKQNPSDLPKATGMVITDMNYRHWDHYVRTNAHPFVADVTAEGVGAGVDVLEGEPYESPLAPFGGIEQIDWSKDSKFIAYTCRKKEGTQYAISTDADIYIYNVETRQTKNLCKPADYVEPKIDATKSMRNQAVNHQAGDMNVGYDVNPKFSPDGKYIAWQSMKNNGYESDRNRLCVYELATGKKTYVTESFDSNVDDYTWSLNSKDLYFIGVWHATVNVYQTNLKGEVKQLTEGNHNYVSISLLGDKKLLAIRQSISQANEIFAITPAKKEKASVQTQLSFENKYIYDQLALGDVKSRWVKTTDGKEMMEWVITPPHFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANGYVIIAPNRRGLPGFGSAWNEEVSTDWTGQCMNDYLSAIDDAANNLPFVDKDRLGAVGASFGGFSVYYLAGIHKKRFKCFISHDGAFNLESMYTDTEEAWFSNWEYDDAYWNKDKSEAAKRTYANSPHLNVDKWDTPILCIHGEKDYRINANQGMGAFNAARLRGIPAELLLYPDENHWVLKPQNSVLWQRTFFNWLDRWLKK
>NZ_CP054010.1|WP_004359637.1|508878_510810_-|membrane-protein-insertase-YidC
MDKRTITGFVLIALILFGFAWWQQPSAEQVAQQRAEFVKDSIAAAKKTQTAKLAAEKQAQQKAAQATDTTALFYSALSGKAQDITLKNSKVELTLSTKGGVVKKAVIKNYIGHNIAVKDGSQDQKNVTLFSGDDQSLNFMLAAKNSNIETKDLIFTPSNVTDSTVTFTAVAGKGKTLTLSYTLGKDYLLNMSLQAEGMGGLFAPNYNQLDINWQDRCRQQERGFTFENRYATLTYKKHDGGTNYLSETSEKEETTEEPMDWVAFKNQFFSAVMIAKDNFATGAKLKSTPLEKSSHYLKHYEANMKAGFDPTGKRPSEFEFYFGPNDFRLLQSVETESKFAKELDMERLVYLGWPLFRIINRWFTLYVFDWLSKVFPMGVVLILITLLLKLITFPMVKKSYMSSAKMRVLKPKLDEATKQFNKPEDQMQKQQAMMQKYSEYGVSPLSGCLPMLIQMPIWIAMFNFVPNAIQLRGQSFLWMHDLSTFDPIFSWNHDVWLVGDHISLTCILFCGANLLYTWFTMQQQKDQMVGQQADQMKMMQWMMFGMPLFFFFMFNDYSSGLNFYYFISLFFSAAIMWALRKTTNEEKLLAILEARREERKNNPKNNMGSGLFARMQALQELQKQQQEELRRKQDELNKKKKGL
>NZ_CP054010.1|WP_036866321.1|510810_512421_-|CTP-synthase
MAETKYIFVTGGVVSSLGKGIISSSIGKLLQARGYNITIQKFDPYINIDPGTLNPYEHGECYVTEDGMETDLDLGHYERFTGIKTTKANSMTTGRIYKSVIDKERRGDYLGKTIQVVPHITDEIKRNIKLLGQKYHYDFVITEIGGTIGDIESAPFLEAIRQLKWELGKRAINLHLTYVPYLKAAGELKTKPTQHSVKELQSVGIQPDVLVMRTEKHLDDDIRKKVAAFCNVDFDCVVQSEDLPSIYDVPVNMLEQGLDAAILRKCGEEVGPKPALGPWKEFLDRQRKATKEVHIGLVGKYDLQDAYKSIREGLLQAGTYNDRKTVITFINSEELTEENVAEKLKGQDGIVVCPGFGQRGIEGKIVAAHYTRTHDIPTFGICLGMQMMVIEFARNVLGYKDANSREIDEKTTHNVIDIMEEQKNITNMGGTMRLGAYECVLRQGSHTFNIYKQEHIQERHRHRYEFNNDYEKEFEKHGMMCVGRNPESDLVEIVEIPGLKWYIGTQFHPEYQSTVLGPHPLFLDFVKTSIENQKNK
>NZ_CP054010.1|WP_036886031.1|513217_513463_+|hypothetical-protein
MELDTTNMCSHLQKKLFNEEGVYYPIWQAMQNDDEITAVIRSRQLHIYRNGKKVLVLPGKAVPKIIREDSLNELLPKDLLK
>NZ_CP054010.1|WP_004359640.1|513459_514185_+|SDR-family-NAD(P)-dependent-oxidoreductase
MKKAIVVGASSGIGHEVARLLIAQGWAVGVAARRIDKLTDLQAIAPERVYTAQIDVNNEDAETSLLQLIEGMGGLDLYFHAAGIGWQNPSLNADIELKTMETNAVGFTRMIGCAYRYFANKGGGHIVCITSIAGTKGLGPAPAYSATKAMQNTYLQALEQLAACKYHNIHFTDIRPGFVDTPLLAGTSHLPMLMTTEKVARSIIKAINSRRHICVIDSRWCVLTYLWRHIPNWIWRRMKLC
>NZ_CP054010.1|WP_004359641.1|514392_515205_+|PepSY-domain-containing-protein
MRKFCLKIHRWFALPLGVVMAILCFSGLAILLIKDLAPLFDMNAKEMPIYTMVVRLHRWLFMKPENAHEGGQSLGRILTAVSAICMSIVLLSGVVIWWPKTKKALKSRLTVSTDKGFRRFVYDSHVSLGIYVFIFLFLMALTGPVFSFGWYRAGMSKLFGQPMPPKEMKMQQPKDGMKQGGTNDKAFAPTNASQMKGQSQTHKEGAKDMKGDQHGKKPKGGMLFKQLHTGTWGGWFSRVLYAIAALIGGFLPISGYYLWWKRRSAKKKKA
>NZ_CP054010.1|WP_172891284.1|515724_517605_+|IS1634-family-transposase
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKTRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYSGVPGWTPGINSLYKITDKLYELKEQLERHLCSVTDDLFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINKEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVIMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDEDYYLEITSPSKAMTESSMNRVWRERFKMDLQRINEGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKKPKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNELNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGETIEMRQCSSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054010.1|WP_004359642.1|518245_519865_+|BACON-domain-containing-protein
MELKKTLYSLMLGGILLCLFSCAKEDEFEMPTLVLSENSIAFDKGVSERNISVTTNQNSWIASSPQEGDWLSLVQDGNVLKVKVTENKIGTERTSYVLVNANGASGKIAVTQSAADVTLDVVPNAIYLPQTGGEKTIDITTNSSVYDVTTSEEVSWLKIVKSEEEIKLIAERNDTYQKREVKLYAKSGSVIREIVVSQSGIQRYLLPIHPGVPQDEHKIMDFELGRGSYLREYQTAMPAYGLEETYTFITPSPIFTLIQYCSTDGINPSQIIMIGDGRKAIDAVKDKAFDKFLTDNGYVRSNSQSDREYTNDKDLLSLKVYVSEKENNEGVNLTFTPIMKQNGDYKTFSKLPFYPLELLQKDNVKLAQIEQYEQKAGSTEEERSLNEHKNTEVSQIQYKLKASTDPSAAYGRIHIFYTTDKDGDAPDNLGSVQIGALLFKDTNLGVWKYGTKWVATKEIKKVLGDEGFSFLRTSGNNHFFVRESDHLVIDVTCVLDNNSPVLALLYSYDPSVSGASSKAVKAQAKMIRNFAAAKKALKF
>NZ_CP054010.1|WP_004359643.1|519901_521503_+|BACON-domain-containing-protein
MRIINIHKLLQFSLLCLLLGIAAGCAENDSFEQPYLNVSEKEISFSNQIGEKTITVNTNCKEWMATTPKAWVHLTQSGNEIAVHLDPNTTGMERSSYILVDGGLAVQKIMVIQSAADITLNLNNGEVILPQAGGTTTVDLKLDATSYDLTQNEQPEWMQVIKKKHGLKFISKPNYGTTERTTKLTIAFAGKNHEVVVKQPGVATFILACNPGNPYSLHKMMDFEYRRGSFLTEYGGPDEVNGIFEESYFFKTPSPLFKDVVYVHDTKYSVPTRIYTRSLTREGVNAVKSQAFQEFMRANGYTRDEKDTNHYVNIKEAFTMDVDIREENNSVVLFFYQMHTQDRSYPTFSSLDLGPIDLLNKTDKKISDVEAYEAGKNSEEMKRQMSKSNEVEAILYKTNDPTLIARTYFFYLHSDAAVPQEKAGSVEQYSLFYSQPNLGIWQYGNEWFVTHEFDKLLTANNFEFVGYNGKHHVYARRSDYLTLAISGGEYADVNNGKAVMQITVLYKPTVFAGSKEQRLAKVERMLKQYNPKK
>NZ_CP054010.1|WP_036885983.1|521518_524275_+|S8-family-serine-peptidase
MRKSIIYLCACALSGMMVTTSCQDSLDSDAGVSNTRSVNIDKDLFAIKGCINVKLAKGTNESIPSTRSGSVEMQSVPSAMTSAMQYSGAYKMERVFKPAGIYEARTVAEGLDRWYTIYFDKSKDVAAVLDQFKKAEGVECAERVLPMARPTVKMTPYSAPEASMQGTGSNFDDPLLPKQWHYYNNGTINPRAVKGADCNVKPVWEKYTTGKKNVIVAVVDGGIDITHEDLKDNLYVNEKEKNGQPNVDDDGNGFVDDIYGYNFVTAKDVVGGTIEPDDGGHGTHVAGTVAARNNNGKGVAGIAGGDGSADSGVRLLSCQIFRNKDEQGDAAAAIKYAADNGAVICQNSWGYSSTAGVTSMPQLLKEAVDYFIKMAGCDANGNQRPDSPMKGGVVMFAAGNENKEFSAYPACYAPTVSVAAMAWDFSKASYSNYAKWVTITAPGGDQDRFGTEAGVLSTVPKKKVASGYAYFQGTSMACPHVSGIAALIASYFGRQGFTNEELKSRLITAYRPYNIDEQNPTYKGKLGKGYIDAEAAFESDTKIAPEKVGTLTLKPDFVDINAEWSIAKDEDKTAAFYRLYIAQGELTADKLKDMTYREINGMGHSLGETLKYDFDDLKDNTTYSVAVVAVDRWGNLSEPQIQKCTTKLNHAPEATNFPTEAIEVMENDRKSFSFNVADPDGHNWDIKATGETKGISYTVKGNTVTVNLVPVLEAGSYNCTFILSDDLGAKAEKSFTFKIVKYIPPQLTKPFENYIIGLDEGVVTIPLTGHYTHSSNTQLTYKATAANGSIAAATISNDNLQLKGMAKGVTRISIAATDGRETSSDGSFQVRVVEKKSAPVYAVYPIPVQRDIHTLLNPEIKQAELVISSTVGERLMKATVTPDKNNVATLDLSKLNPGTYKLTVYTSKGNHTQMFIKR

Crispr_ID: NZ_CP054010_3

• CRISPR_ID: NZ_CP054010_3
• CRISPR_location: 870239-870379
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_3

Consensus_repeat	Method
CTTGTTCCTATGTTACTTTGTCTTTTATTTACCCTGTCTACAAGCAACTTGTT	CRISPRCasFinder

spacers of NZ_CP054010_3

>3.1|870292|35|NZ_CP054010|CRISPRCasFinder
AACTCGTCTACTCGTTTACATGTTAACTTTAAAAC

CRISPR arrays and Neighbor proteins around NZ_CP054010_3

CRISPR arrays

The CRISPR arrays of NZ_CP054010_3

>merge|NZ_CP054010|3|870239-870379|CRISPRCasFinder
CTTGTTCCTATGTTACTTTGTCTTTTATTTACCCTGTCTACAAGCAACTTGTTAACTCGTCTACTCGTTTACATGTTAACTTTAAAACCTTGTTCCTATGTTACTTTGTCTTTTATTTACCCTGTCTACAGGCAACTTGTT

>NZ_CP054010|3|3|870239-870379|CRISPRCasFinder
CTTGTTCCTATGTTACTTTGTCTTTTATTTACCCTGTCTACAAGCAACTTGTT	AACTCGTCTACTCGTTTACATGTTAACTTTAAAAC
CTTGTTCCTATGTTACTTTGTCTTTTATTTACCCTGTCTACAGGCAACTTGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359213.1|860928_861381_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	unknown	unknown	gnl|CDD|367917
NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_036885802.1|872723_872993_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	unknown	unknown	gnl|CDD|372993
NZ_CP054010.1|WP_004359218.1|855615_857823_+|sodium-translocating-pyrophosphatase	unknown	unknown	gnl|CDD|376979
NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein	unknown	unknown	gnl|CDD|274507
NZ_CP054010.1|WP_004359216.1|858976_859234_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP054010.1|WP_004359214.1|860312_860921_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	unknown	unknown	gnl|CDD|379166
NZ_CP054010.1|WP_036885807.1|859634_860129_+|outer-membrane-beta-barrel-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_004359217.1|858714_858921_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	unknown	unknown	gnl|CDD|379719

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	gnl|CDD|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.18595e-10
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.42649e-43
NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.01754e-24
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	gnl|CDD|367917	pfam04383, KilA-N, KilA-N domain. The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.	1.20438e-11
NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.59219e-57
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	1.61174e-12
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	gnl|CDD|372993	pfam14274, DUF4361, Domain of unknown function (DUF4361).	6.672e-15
NZ_CP054010.1|WP_004359218.1|855615_857823_+|sodium-translocating-pyrophosphatase	gnl|CDD|376979	pfam03030, H_PPase, Inorganic H+ pyrophosphatase. The H+ pyrophosphatase is an transmembrane proton pump involved in establishing the H+ electrochemical potential difference between the vacuole lumen and the cell cytosol. Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of photo-trophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organisms as disparate as thermophilic Archaea and parasitic protists.	0
NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein	gnl|CDD|274507	TIGR03296, hypothetical_protein, M6 family metalloprotease domain. This model describes a metalloproteinase domain, with a characteristic HExxH motif. Examples of this domain are found in proteins in the family of immune inhibitor A, which cleaves antibacterial peptides, and in other, only distantly related proteases. This model is built to be broader and more inclusive than pfam05547.	7.98232e-55
NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	5.29642e-48
NZ_CP054010.1|WP_004359214.1|860312_860921_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	2.41987e-114
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	gnl|CDD|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	2.76184e-33

Protein sequences

>NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTVRTYILAGVAALALTSCNDYLTTVPKDAMSPATTWKTGDDAEKFLVGCYDGWESGAALLYWDAGSDFAYNNFPWEGFTNIGNGSLSPSSPGWSFYDYTIIGRCNTFLENVDKCVFSSDAVKKDLVAQVKAIRAYNYFRMGFLYGGVPIVKPFTSAQEARVPRNTEQEVKDLVFKDLDEAIADINTTPAARGRIAKGAALAMKMRAALYWGDYQKAKDAAQAIIDLGKYELDPDYTNLFKLAGVDSKEIILAVQYKSGTRPLGTIGQLYNNGDGGWSSVVPTQKCVDNYEMSNGMTITEAGSGYDATHPFHGRDPRMAMTILYPGCDWEGSIFNTLDENVNGKKNPNYPTNAANSSKTALTWRKYLDPKTQYADVWDTEACPIVFRYAEVLLTWAEAENELNGPSANVYTMIDKVRTRVGMPAVDQTKYNTKEKLRELIRRERGSEFAGEGLRRADILRWTSNGKMVAETVLNGPLNRITGTINTSATDPTMRAVVSGTSKVEDRTFQTFNRYLPIPQWNISDNPKLEQNPGYAK
>NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor
MSNFMKVSQNRRKHPPFVTGSLAFSFALGLMAFAPSPVLANVDANTSMSVQQQKQSINGVVKDANGDPVIGASILANGTPVGVTDMDGRFSISVALGTELKISYVGFTTQSVMVRSGVTNYNITLKDENSALSEVVVVGYGTQKKANLSGSVAQLDSKALENRPISNVSSGLQGLLPGITVTGADGAPGLDNGTILVRGVGTLNSATPYILIDGVEAGTLNSLDPEDIASISVLKDASSAAIYGSKASNGVILVTTKRGQNGAPKVSYSGYFGIQNATALMERMNSADAAYYYNKALERSGKAPRFSDEAIKKFRDGSDPYNYPNTDWYDLAFKTAWQNRHNVNITGGNEYVKYLASAGYLKQSSILPNAGREQFNGRANLDMVLSKRITAHLNLAYIQNNYRDASSAYAGGSSDQIIRQLNIIAPWIVYKYEDGTYGTVSDGNPMAWLESGMTVNRNNRNFTGMIGIDYQIIKDLKLTLQGAYVDNSQRYSYFQKFIQYNPNKASDPNKLEIAHYDWHRTTFDAFLNYDKSFAKHNFKAMLGWHTERFKYLPDWMYRKNFPNNELTDMNAGDASTQQNAGNTRELAMVSYFGRLNYDYAGRYLFEANFRSDASSRFAEGHRWGFFPSFSAAWRISEEPFMESSKSWLNNLKLRASWGQLGNQDALNDYYPWMNTYNLNAKYPFGGQLTPGYYQGSYHLETISWERSTTWGVGLDFTLFGGLTGSLDYYNRKTTGIIMNVSAPAEFALGAYKDNIGALRNQGVELSLAYAKQLNKDWTINVGANFAYNKNKILDLGEGTEYIEDKDDRNRRTAIGQQYKSYFMYKATGKFFNSQQEADDFTAKYGNPFGRKFMAGDLIYEDTNGDGKLDTNDRIYTKHTDIPAITYGFNLGATWKNVDLSMIWQGVGAVSHIYNREVLGEFSGDASHPSTLWKDSWTDDNHNAKLPRVFETGNSPSDMTRAMSTFWLWNTAYLRLKTLQLGYTLPKSALKAVGLEKVRIYYAGENLLTFDALPFNIDPEVTSERGSSYPLLRSHSIGINITF
>NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase
MEKKQHVEVRLRAMEPEDLDMLYHIENDRSLWNISATNVPYSRYALHNYIADAKNDIYIDGQLRMMIENREQEIVGVIDLVNFDPKHQRAEMGIIIMKPFRQKGYAQAAISALIDYTRNGLHLKQIYAVVDVDNEVSIRCLSSIGFTNGSILKEWLYCDGQYKDARVMQLFI
>NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein
MKLSVVIVNYNVKYYLQQCLESLQRALKGVEAEVFVVDNHSHDGSVAYLRSRFPDVHFIASTHNLGFAGGNNIAIRQSKGEYVLLLNPDTVVGEEVIHASIDFMDSHLTAGGHGVQMLTHCGERALESRRGLPSPIVSFYKMVGLCKHFPQSDRFAHYYMGSLSWDVPGKIEVISGAYCFLRRAALDKVGLLDEDFFMYGEDVDLSYRLLKGGFENWYLPVRILHYKGESTQKSSFRYVHVFYDAMLIFFRKHYGGMNALWRLPIKTAIYVKAFGSLIGTTIRATRKKLGFRTSKDKSFPHYIFVAGEDVMGKCQRLATDNALVAEYRVADKDSLQHTHANLIKEFGGKNRPYCIVYDTDLFSYQDILNVFAEQPKQNIHIGFYHRKENRVVTMMEVIGD
>NZ_CP054010.1|WP_004359213.1|860928_861381_+|hypothetical-protein
MDKTRKILLTEFFGSCLITLLIIAVYELELILPGAWADVESSNMVTVQFLMQLLTLATIPLALFLFKIGYVHSDLHTDESHVSRKLLFWGSVRIMMLCVPMILNTFFYYAFGDSVSFFYLAVILALSLFFVFPNKKRCEHECSMDNSEQA
>NZ_CP054010.1|WP_004359214.1|860312_860921_+|recombination-protein-RecR
MQQYPSQLLERAVEAFSQLPGVGRKTALRLVLHLLRQSTEDVDSFADAVIRVKHDVKYCKVCHNISDNEVCSICSDPRRDASVVCVVENIQDVMAIENTQQFHGLYHVLGGIISPMDGIGPHDLEIESLVERVEEGTVKEVILALASTMEGDTTNFYISRKLKDTGVKLSVIARGISVGDELEYTDEVTLGRSILNRTPFES
>NZ_CP054010.1|WP_036885807.1|859634_860129_+|outer-membrane-beta-barrel-protein
MIKRFMLFVAAMVVSISASAQFQEGKGYLGASLTGLDLHYNGQDGFNLGVQAKAGYFPWDNLMVLATFDAAHNGSEAVADHISVGVGGRYYITQNGLYLGAGVKLLHANHNYNDLMPGVEVGYAFFINRSVTIEPAIYYDQSFKTHNYSNIGLKVGLGIYLFDD
>NZ_CP054010.1|WP_004359216.1|858976_859234_+|hypothetical-protein
MKRIKIVRVLATYICHDPFAYSPIWTWDGFPPIIYTERERILPVLKEWEHKGYLTLIYDEKIAFILNVEKLPSKEKLIEESRNIK
>NZ_CP054010.1|WP_004359217.1|858714_858921_+|hypothetical-protein
MSPIVDWNLLDVLNKNIRNNYERIRPILLKWQENGYIKLIEDNEIAFSFIPEKLPSKEKLIEESLNFK
>NZ_CP054010.1|WP_004359218.1|855615_857823_+|sodium-translocating-pyrophosphatase
MEHIPQVFWLIPIASVCALGMAWYFFKSMMKAEEGTPRMVEIAEYVRRGAMAYLKQQYKVVLIVFVVLAIVFAIMAYGFNAQNEWVPFAFLTGGFFSGLAGFFGMKTATYASARTANAARNGLNNGLKIAFRSGAVMGLVVVGLGLLDIAIWFIVLTWFYSDKMTTSEMLITITTTMLTFGMGASTQALFARVGGGIYTKAADVGADLVGKVEANIPEDDPRNPATIADNVGDNVGDVAGMGADLYESYCGSILSTAALGATAFAASSGDMQLKAVIAPMLIAAVGVFLSLFGIFLVRTKEGATMKDLLHALGLGTNTAAVLIAAVSFLILYLLGLENWLGVSFSVIAGLAAGVLIGQATEYYTSQSYMPTKAISEASHTGSATVIIKGIGTGMISTCVPVLSISVAIMLSYLCANGFDMSMSALSIQHGLYGIGIAAVGMLSTLGITLATDAYGPIADNAGGNAEMSELGAEVRQRTDALDALGNTTAATGKGFAIGSAALTALALLASYIEEIKIAMARVGTQMTNVAGETIDATKATIPDFMNFFQVNLMNPKVLVGAFIGAMAAFLFCGLTMGAVGRAAGKMVEEVRRQFREIKGILEGTGTPDYGRCVEISTQSAQHEMIIPSLLAIIIPVVVGLLLGVAGVLGLLVGGLAAGFTLAVFMSNAGGAWDNAKKYVEEGNFGGKGSDAHKATIVGDTVGDPFKDTSGPSLNILIKLMSMVSIVMAGLTVACL
>NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein
MKKIITLLASVLLATSSFAIPAMRMWRSFKQADGTILKVMTVGDEHFNYALTEDNIPVLPYNGSYYYARIEDNQLVPSSVLAHNKALRKGKEELVAAAIQQVRQLQKQHEMHVNSKPFGEGLGMTWEGKKKGLVILVEFEDVAFKDPKNVLTLKPREKDVKTLYENMLNKVGYTNDNGAIGSVHDYFLDQSNGKFDLTFDVVGPVKLKHPHQFYGERTANMNDANAPQMIIDACNAIQGVDFSKYDWDDDGEVEQVYVIYAGEGEATGGEPNTIWPHKYSLTDAGLDALTFNGQTINTYACSNEIIRAKVNEKSRIFYSGIGTICHEFSHCLGLPDFYDTCGGNNIGSGRYDLMCAGSYNGGPESLINVYGGTGIGTVPAGYDAYEKAYMGWLKPITLGDEAVEVKNMKGLAEGGDAYFLYNPDTKNEYYILENRTPYRWDTELPGHGLMVFHVDFDAYSWRMNNLNAASVQRHPRFTIVPADARLDHDTQNSDPFPTGLNNSLTKSTDPRLSFYTNYNVSSQAGIKQVARNADNTISFSYTPLQTSAGINTLSVDREQSANTYTLSGVKVADNQNLHNQIVIVKGKKVRK
>NZ_CP054010.1|WP_036885802.1|872723_872993_-|hypothetical-protein
MEETPSPYRWFGYMFVWMLACLLLLQEGEGSELFIFILLLVAIVLNGYCAYRFALEKWTFLAILAFVVAMVLDFFPIVAYFVIMEICMA
>NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein
MTKKGEIFVKDVAIKTMTKDGIDYICITDIARQKNAAEPKDVVKNWMRQKNTLEYLGLWEKLNNPNFKGVEFDPLLAEAGSNSFTMSPTRWVELTAAIGVFTKNGAGGGTFAQRDIAFKFANWVSVEFELYLVMEFQRLKAKEQELIGWTAKRELSKINYRIHTDAIKSHLIPEKVTPTQANIIYAEEADVLNVAMFGMTARQWRESNPDLKGNIRDYASVNELICLSNMENINAVLINDDIPQGERLVRLNQIAIHQMQILERNSNRNLLR
>NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA
MATVDDKKIIFSMVGVSKIIPQNQKQILKNIYLSFFYGAKIGIIGLNGAGKSTLMKIIAGLVEPTQGEVVWSPGYSVGYLPQDPPLDEAKTVKENVMEGVQHIYDALKEYDDINVKFGLEEYYSDADKMDKLMQRQAELQDIIDATDAWNIDSRLERAMDALRCPKGDLPVTNLSGGERRRVALCRLLLQKPDVLLLDEPTNHLDAESIDWLEQHLQQYEGTVIAVTHDRYFLDDVSEWILELDRGEGIPWKGNYSSWLDQKTKRMEQEEKSASKRRKTLERELEWVRMAPKARQAKGKARLNSYEQMLNEEQKQREEKLEIFIPNGPRLGNKVIEAQHVKKAFGEKVLFNDLNFMLPPNGIVGVIGPNGAGKTTLFRLIMGLEQADGGTFEVGETVKLAYVDQQHKDINPNKTVYDVVSQGNETIRMGGRDINSRAYLSRFNFSGTDQSKLCSVLSGGERNRLQLAMALKQEGNVLLLDEPTNDIDVNTLRALEEGLEAFAGCAVVISHDRWFLDRICTHILAFEGNGEVVYFEGGFSDYEINKARRLGNEEIKKGRYRKLMEE
>NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein
MFVLFFLCFSIYGKAQTAPKKLTAPSPERFQAINDSILAEGMWLYTYEKLAWRATDSLMKYNVKREEINSATAFEEGNLTWRYIFANLDKEQTVFELTLHLSNDTSFYVCSATPRKLKPTEIEQLKAKQIAPRKVIKEKGDSIFLSNTSGLNWDLIPLTNGCYRLYLLHGTTKHGVIPIGDDYAFDFDKDMNILSWRRFHRSFLEQPITMNGEKITEVMHSHTPMTPYFTTTDIANYMLYGCDLYGIKRFSVLSTAFADTSYLTTFDVEKMKLTSTVYTVK
>NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein
MKRLQLIVPMLACCLALPCLSFTDVKDSYLVLQVDTTQKYEQYSYVNEKGETVVPSNRYLLCYTDTIRTIGFVLKPNVGCVAINTQGQELFNVYMVDNGNDYPVNGLFRILDESGQKMGVANMEGKVIVNPKYDAIFPYHDGLAAVAVGSKTVRPADDPEHEYTVGGKWGFIDKQGNEVIPLEYDSIANYRRFVNGKALVLKHGKWIKLSIRQKKR
>NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein
MLFERFLRKKTLMAALALTAAVPSVAKASMLSAAPTADGENQKLKPGVYYIVNDKRQKGTDLHVFVNDEGTLHGQHYGSPSTDFSDLFLLRAKDGRYTIQSLKNAKYVQSVGQNNEVYKTANDAYKFRIIYQTESSGTGKSYFNIYNSNAEDWCWHIDAQKNIVRWKPLMDNGIRAVGPSEFRFDPVTTLTNEQVLARLAQLTKVVDPTKDLTKYYQIVSDTYGRSMREDFIVGELSTSGFNSSDYSYYWKLERLANGRYVFQNAVTGKYIVPQNGQTSRSYTTAEGKGTGFDLQRNTDDPYGLAFEMVDANNVGIHCAESQGYHPVGWYTHNEANKWVFKEATLDPAKLKEQQEAYKARVDLTKNVDVYAEKVAKYFTNSAATEVTAATKAMTDEALKAQMTTEGVPQGLQEVVLKIKNQSWTAYPSGRNWEKLFRIADYKVYSENNYNAWARSMGIGYDYGSMTNPTGITARDGEDLFVFLGDDIPQNATVQIELVPLGTRSAGKYYSLKKGLNIILNQGENNVFVNYIGRTFNNGKYLRDYKPMNIHIEGGKVNGYFDLTKGNTNEDWQKMQSDGLVWAKAFNMKGELVVMNMPGADCKRYTPVHMKELVEIWNSIVQREDDLMGFRAAKRDKCNNVLNATAVDHGYMYATTGGTYYNYNTLGDVLNYDKMKWGNGTLWGPAHEFGHNHQQLFNTAGMTEISVNMYSNMVMFTSGRVTSRSENCSYTDVDGKKYDGVCESAVSTYADRFANKKKWFEYGTWGTTQMYYKLYMMFHSTGLDNQFWHKCLDYLRTHRLEGQGTANCQGQNDYLLFAKACSYAAQQDLSSFFEAWGHFYDVNGSVIGDYSNTTMYTTRAQWMEAKKFMQKYPKGPANNMIFIDDHIRRTPATYPGHAAGEMREDFNGAVRVGRMGDFGSWDQFCPDSLGQGYAIIKTQSDANGKRTYTMEAKNSHVVGFKIYNSKGQLIYFANTKTFTIPKKVMEDAKNDIKVKVCGSDGSEVDPGTVPLGITTFSAQANGGKVDVYSIYGVLVRSKVNAETALEGLPNGVYVVGGKKVVVGK
>NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein
MKLKINFLFILSVLFVGTLGLASCATDYDTDFTGKELEVPHSSQRMIAFNKEGGEQQIAVETNVALDEWKAESNADWLTVTKNADGKGVTVKTPAYDGFKAREAKVTISHGERASYEIKVSQMGFESVLRIPEQNPFFNREGTFYSLLESKVTSIDVPVETNLNLDHIIVPDTVSFVRLDASKTVKENGIVKLHFDMDPNTTSEKRYCTVRLKSSDNWDASIEYVIEQAAKGYKVRPIYPVETKQASVEMIDLGRTYRVPFQRTAVDGNYEVIIPDNAKDWLSTTKKFIAGSEVVFTTTLNTTDSPRSCDVVCKPSNGSTQPFTIHVTQQAFQDIVPTGVSELNVTPGKGQFNVSWKAPDEVNYEKVIVRAKSNMPGVPESVKEVAATETSCVLNDVFNFAGNYTITVTTQGLRGKNTDAPATATAQANEWSESVEIPLTAAMVSSNSMQPGHEIGSAVDGNKTTYFQTKSNGSTSDPRPHIDITLNEGINGTFYLAFDENKVTSNDRNPKKANIYASSDVITATTRPLTQTNFRSANAVSEPLSYTKTNGVTVTHIRFEPTQRKNGTNINNGGGSSYWYLAELHLYVYHDEAWKREQLGL
>NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein
MKKYKYILGCALAAVALSSCNNYDFEQNFYPHKVGLMAGTNRIYDRTTVELSTVENGTASVQLVANLSGSQLADRDYHVTIAHDDSLFNAYNKSNFDIDSTKFARLLPQNCYEDPAMAGTIPSGSNKCLFDIKLKNLGTLSPDSTYFLNYKIVSHDASALATDNNKLGVKLDHVLIKVTWKNAYGSTAEGWNYQLVSSQVTNLETKSTTRPTNTVRAFPVAANAVRFLAGDEKWDNYEKALHDINVKSIVATIGSKTVTNPSAYNVTLKPYKQDSLEVEMLTPVGEYNNTFLLNELGGSASTNPTYFKEFRLHYRYRVMKNAKQNDGTWKAGPWKEVLSKLRYQYNPRADKL
>NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKHILALGAVAALFSGMTFTSCNFLDQDDNFNAIFKEDSVFHSAQNANGYLFATPTMFPSAGNIWGNSWTPGETASDEICVRWQTNEFWGAKFTVGNVNAENVPNWGYWYQMYKIINRCNRMLANVDKIGDMSNNDKADYKAMVHFIRGYAYYVLLQNWGPCLIVNDEVISTSEKADYYDRERATMDESIDYICNEFAQSLPGLKRPSEQSTAYFGRPTKGTALALIARLRLLQASPTFNGGTYAKRCFGEWKRKSDGKYYVNQDYDAKRWAVAAAAAKQVIDLNYYTLFTVDADKDNPYPLDASVPTAKFPDGAGGIDPYHSFADMFNGEGTAKVNREFIWADEYSGPVMNYSRHSFPVNYGGWGGMSVPQRVIDCFLMKDGKKPAESPLYEADLTKHVNQKKSIGDCDMANGTPLAYTNRSARFYASIGFPGRIWKMNSTTDGSYNNQTFWYSIDDSKAGKNAAGNNPNDYCISGYVPFKYIHPDDSWHGKDGASVIPKPFPIIRYAEILLIYCEAANHIQGSETVKTWDVSGRLVDVAVTRDEAAMARYFNMIRYRVGLPGVEAATLSSENAFDEVIKNERQVELFNEGYRYFDTRRWGTYFTEDANSSNWRGLDVYSEKKGNNDGPFFNLVTINEQNIRDRKALPRMVFLPLMHRELLKSPKMDQNPGWDR

Crispr_ID: NZ_CP054010_4

• CRISPR_ID: NZ_CP054010_4
• CRISPR_location: 878463-878584
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_4

Consensus_repeat	Method
CCAAAGGAGGGGAGCTGCCTAACGGATAAAGA	CRISPRCasFinder

spacers of NZ_CP054010_4

>4.1|878495|58|NZ_CP054010|CRISPRCasFinder
CTTGAAGAGTAAACCTATTCTATATTAGCATTTTCACATACCACCTCCCCCAACCCCT

CRISPR arrays and Neighbor proteins around NZ_CP054010_4

CRISPR arrays

The CRISPR arrays of NZ_CP054010_4

>merge|NZ_CP054010|4|878463-878584|CRISPRCasFinder
CCAAAGGAGGGGAGCTGCCTAACGGATAAAGACTTGAAGAGTAAACCTATTCTATATTAGCATTTTCACATACCACCTCCCCCAACCCCTCCAAAGGAGGGGAGCTGCCTAACAGATAAAGA

>NZ_CP054010|4|4|878463-878584|CRISPRCasFinder
CCAAAGGAGGGGAGCTGCCTAACGGATAAAGA	CTTGAAGAGTAAACCTATTCTATATTAGCATTTTCACATACCACCTCCCCCAACCCCT
CCAAAGGAGGGGAGCTGCCTAACAGATAAAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	unknown	unknown	gnl|CDD|379719
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|269882
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	unknown	unknown	gnl|CDD|271323
NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	unknown	unknown	gnl|CDD|367917
NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NZ_CP054010.1|WP_036885802.1|872723_872993_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	unknown	unknown	gnl|CDD|226195
NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein	unknown	unknown	gnl|CDD|274507
NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	unknown	unknown	gnl|CDD|372993
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	unknown	unknown	gnl|CDD|379166
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	unknown	unknown	gnl|CDD|153100

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	gnl|CDD|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.18595e-10
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	gnl|CDD|269882	cd06596, GH31_CPE1046, Clostridium CPE1046-like. CPE1046 is an uncharacterized Clostridium perfringens protein with a glycosyl hydrolase family 31 (GH31) domain. The domain architecture of CPE1046 and its orthologs includes a C-terminal fibronectin type 3 (FN3) domain and a coagulation factor 5/8 type C domain in addition to the GH31 domain. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.	0
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.42649e-43
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	gnl|CDD|271323	cd14953, NHL_like_1, Uncharacterized NHL-repeat domain in bacterial proteins. This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	9.68928e-20
NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.59219e-57
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	gnl|CDD|367917	pfam04383, KilA-N, KilA-N domain. The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.	1.20438e-11
NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.01754e-24
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	gnl|CDD|226195	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism].	4.61922e-33
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	1.61174e-12
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein	gnl|CDD|274507	TIGR03296, hypothetical_protein, M6 family metalloprotease domain. This model describes a metalloproteinase domain, with a characteristic HExxH motif. Examples of this domain are found in proteins in the family of immune inhibitor A, which cleaves antibacterial peptides, and in other, only distantly related proteases. This model is built to be broader and more inclusive than pfam05547.	7.98232e-55
NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	5.29642e-48
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	gnl|CDD|372993	pfam14274, DUF4361, Domain of unknown function (DUF4361).	6.672e-15
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	gnl|CDD|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	2.76184e-33
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	6.0924e-58

Protein sequences

>NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein
MKRLQLIVPMLACCLALPCLSFTDVKDSYLVLQVDTTQKYEQYSYVNEKGETVVPSNRYLLCYTDTIRTIGFVLKPNVGCVAINTQGQELFNVYMVDNGNDYPVNGLFRILDESGQKMGVANMEGKVIVNPKYDAIFPYHDGLAAVAVGSKTVRPADDPEHEYTVGGKWGFIDKQGNEVIPLEYDSIANYRRFVNGKALVLKHGKWIKLSIRQKKR
>NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein
MFVLFFLCFSIYGKAQTAPKKLTAPSPERFQAINDSILAEGMWLYTYEKLAWRATDSLMKYNVKREEINSATAFEEGNLTWRYIFANLDKEQTVFELTLHLSNDTSFYVCSATPRKLKPTEIEQLKAKQIAPRKVIKEKGDSIFLSNTSGLNWDLIPLTNGCYRLYLLHGTTKHGVIPIGDDYAFDFDKDMNILSWRRFHRSFLEQPITMNGEKITEVMHSHTPMTPYFTTTDIANYMLYGCDLYGIKRFSVLSTAFADTSYLTTFDVEKMKLTSTVYTVK
>NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA
MATVDDKKIIFSMVGVSKIIPQNQKQILKNIYLSFFYGAKIGIIGLNGAGKSTLMKIIAGLVEPTQGEVVWSPGYSVGYLPQDPPLDEAKTVKENVMEGVQHIYDALKEYDDINVKFGLEEYYSDADKMDKLMQRQAELQDIIDATDAWNIDSRLERAMDALRCPKGDLPVTNLSGGERRRVALCRLLLQKPDVLLLDEPTNHLDAESIDWLEQHLQQYEGTVIAVTHDRYFLDDVSEWILELDRGEGIPWKGNYSSWLDQKTKRMEQEEKSASKRRKTLERELEWVRMAPKARQAKGKARLNSYEQMLNEEQKQREEKLEIFIPNGPRLGNKVIEAQHVKKAFGEKVLFNDLNFMLPPNGIVGVIGPNGAGKTTLFRLIMGLEQADGGTFEVGETVKLAYVDQQHKDINPNKTVYDVVSQGNETIRMGGRDINSRAYLSRFNFSGTDQSKLCSVLSGGERNRLQLAMALKQEGNVLLLDEPTNDIDVNTLRALEEGLEAFAGCAVVISHDRWFLDRICTHILAFEGNGEVVYFEGGFSDYEINKARRLGNEEIKKGRYRKLMEE
>NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein
MTKKGEIFVKDVAIKTMTKDGIDYICITDIARQKNAAEPKDVVKNWMRQKNTLEYLGLWEKLNNPNFKGVEFDPLLAEAGSNSFTMSPTRWVELTAAIGVFTKNGAGGGTFAQRDIAFKFANWVSVEFELYLVMEFQRLKAKEQELIGWTAKRELSKINYRIHTDAIKSHLIPEKVTPTQANIIYAEEADVLNVAMFGMTARQWRESNPDLKGNIRDYASVNELICLSNMENINAVLINDDIPQGERLVRLNQIAIHQMQILERNSNRNLLR
>NZ_CP054010.1|WP_036885802.1|872723_872993_-|hypothetical-protein
MEETPSPYRWFGYMFVWMLACLLLLQEGEGSELFIFILLLVAIVLNGYCAYRFALEKWTFLAILAFVVAMVLDFFPIVAYFVIMEICMA
>NZ_CP054010.1|WP_036885803.1|870527_872303_+|M6-family-metalloprotease-domain-containing-protein
MKKIITLLASVLLATSSFAIPAMRMWRSFKQADGTILKVMTVGDEHFNYALTEDNIPVLPYNGSYYYARIEDNQLVPSSVLAHNKALRKGKEELVAAAIQQVRQLQKQHEMHVNSKPFGEGLGMTWEGKKKGLVILVEFEDVAFKDPKNVLTLKPREKDVKTLYENMLNKVGYTNDNGAIGSVHDYFLDQSNGKFDLTFDVVGPVKLKHPHQFYGERTANMNDANAPQMIIDACNAIQGVDFSKYDWDDDGEVEQVYVIYAGEGEATGGEPNTIWPHKYSLTDAGLDALTFNGQTINTYACSNEIIRAKVNEKSRIFYSGIGTICHEFSHCLGLPDFYDTCGGNNIGSGRYDLMCAGSYNGGPESLINVYGGTGIGTVPAGYDAYEKAYMGWLKPITLGDEAVEVKNMKGLAEGGDAYFLYNPDTKNEYYILENRTPYRWDTELPGHGLMVFHVDFDAYSWRMNNLNAASVQRHPRFTIVPADARLDHDTQNSDPFPTGLNNSLTKSTDPRLSFYTNYNVSSQAGIKQVARNADNTISFSYTPLQTSAGINTLSVDREQSANTYTLSGVKVADNQNLHNQIVIVKGKKVRK
>NZ_CP054010.1|WP_004359209.1|867886_869500_+|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTVRTYILAGVAALALTSCNDYLTTVPKDAMSPATTWKTGDDAEKFLVGCYDGWESGAALLYWDAGSDFAYNNFPWEGFTNIGNGSLSPSSPGWSFYDYTIIGRCNTFLENVDKCVFSSDAVKKDLVAQVKAIRAYNYFRMGFLYGGVPIVKPFTSAQEARVPRNTEQEVKDLVFKDLDEAIADINTTPAARGRIAKGAALAMKMRAALYWGDYQKAKDAAQAIIDLGKYELDPDYTNLFKLAGVDSKEIILAVQYKSGTRPLGTIGQLYNNGDGGWSSVVPTQKCVDNYEMSNGMTITEAGSGYDATHPFHGRDPRMAMTILYPGCDWEGSIFNTLDENVNGKKNPNYPTNAANSSKTALTWRKYLDPKTQYADVWDTEACPIVFRYAEVLLTWAEAENELNGPSANVYTMIDKVRTRVGMPAVDQTKYNTKEKLRELIRRERGSEFAGEGLRRADILRWTSNGKMVAETVLNGPLNRITGTINTSATDPTMRAVVSGTSKVEDRTFQTFNRYLPIPQWNISDNPKLEQNPGYAK
>NZ_CP054010.1|WP_004359210.1|864735_867864_+|TonB-dependent-receptor
MSNFMKVSQNRRKHPPFVTGSLAFSFALGLMAFAPSPVLANVDANTSMSVQQQKQSINGVVKDANGDPVIGASILANGTPVGVTDMDGRFSISVALGTELKISYVGFTTQSVMVRSGVTNYNITLKDENSALSEVVVVGYGTQKKANLSGSVAQLDSKALENRPISNVSSGLQGLLPGITVTGADGAPGLDNGTILVRGVGTLNSATPYILIDGVEAGTLNSLDPEDIASISVLKDASSAAIYGSKASNGVILVTTKRGQNGAPKVSYSGYFGIQNATALMERMNSADAAYYYNKALERSGKAPRFSDEAIKKFRDGSDPYNYPNTDWYDLAFKTAWQNRHNVNITGGNEYVKYLASAGYLKQSSILPNAGREQFNGRANLDMVLSKRITAHLNLAYIQNNYRDASSAYAGGSSDQIIRQLNIIAPWIVYKYEDGTYGTVSDGNPMAWLESGMTVNRNNRNFTGMIGIDYQIIKDLKLTLQGAYVDNSQRYSYFQKFIQYNPNKASDPNKLEIAHYDWHRTTFDAFLNYDKSFAKHNFKAMLGWHTERFKYLPDWMYRKNFPNNELTDMNAGDASTQQNAGNTRELAMVSYFGRLNYDYAGRYLFEANFRSDASSRFAEGHRWGFFPSFSAAWRISEEPFMESSKSWLNNLKLRASWGQLGNQDALNDYYPWMNTYNLNAKYPFGGQLTPGYYQGSYHLETISWERSTTWGVGLDFTLFGGLTGSLDYYNRKTTGIIMNVSAPAEFALGAYKDNIGALRNQGVELSLAYAKQLNKDWTINVGANFAYNKNKILDLGEGTEYIEDKDDRNRRTAIGQQYKSYFMYKATGKFFNSQQEADDFTAKYGNPFGRKFMAGDLIYEDTNGDGKLDTNDRIYTKHTDIPAITYGFNLGATWKNVDLSMIWQGVGAVSHIYNREVLGEFSGDASHPSTLWKDSWTDDNHNAKLPRVFETGNSPSDMTRAMSTFWLWNTAYLRLKTLQLGYTLPKSALKAVGLEKVRIYYAGENLLTFDALPFNIDPEVTSERGSSYPLLRSHSIGINITF
>NZ_CP054010.1|WP_004359211.1|862587_863106_+|GNAT-family-N-acetyltransferase
MEKKQHVEVRLRAMEPEDLDMLYHIENDRSLWNISATNVPYSRYALHNYIADAKNDIYIDGQLRMMIENREQEIVGVIDLVNFDPKHQRAEMGIIIMKPFRQKGYAQAAISALIDYTRNGLHLKQIYAVVDVDNEVSIRCLSSIGFTNGSILKEWLYCDGQYKDARVMQLFI
>NZ_CP054010.1|WP_004359212.1|861381_862584_+|glycosyltransferase-family-2-protein
MKLSVVIVNYNVKYYLQQCLESLQRALKGVEAEVFVVDNHSHDGSVAYLRSRFPDVHFIASTHNLGFAGGNNIAIRQSKGEYVLLLNPDTVVGEEVIHASIDFMDSHLTAGGHGVQMLTHCGERALESRRGLPSPIVSFYKMVGLCKHFPQSDRFAHYYMGSLSWDVPGKIEVISGAYCFLRRAALDKVGLLDEDFFMYGEDVDLSYRLLKGGFENWYLPVRILHYKGESTQKSSFRYVHVFYDAMLIFFRKHYGGMNALWRLPIKTAIYVKAFGSLIGTTIRATRKKLGFRTSKDKSFPHYIFVAGEDVMGKCQRLATDNALVAEYRVADKDSLQHTHANLIKEFGGKNRPYCIVYDTDLFSYQDILNVFAEQPKQNIHIGFYHRKENRVVTMMEVIGD
>NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein
MLFERFLRKKTLMAALALTAAVPSVAKASMLSAAPTADGENQKLKPGVYYIVNDKRQKGTDLHVFVNDEGTLHGQHYGSPSTDFSDLFLLRAKDGRYTIQSLKNAKYVQSVGQNNEVYKTANDAYKFRIIYQTESSGTGKSYFNIYNSNAEDWCWHIDAQKNIVRWKPLMDNGIRAVGPSEFRFDPVTTLTNEQVLARLAQLTKVVDPTKDLTKYYQIVSDTYGRSMREDFIVGELSTSGFNSSDYSYYWKLERLANGRYVFQNAVTGKYIVPQNGQTSRSYTTAEGKGTGFDLQRNTDDPYGLAFEMVDANNVGIHCAESQGYHPVGWYTHNEANKWVFKEATLDPAKLKEQQEAYKARVDLTKNVDVYAEKVAKYFTNSAATEVTAATKAMTDEALKAQMTTEGVPQGLQEVVLKIKNQSWTAYPSGRNWEKLFRIADYKVYSENNYNAWARSMGIGYDYGSMTNPTGITARDGEDLFVFLGDDIPQNATVQIELVPLGTRSAGKYYSLKKGLNIILNQGENNVFVNYIGRTFNNGKYLRDYKPMNIHIEGGKVNGYFDLTKGNTNEDWQKMQSDGLVWAKAFNMKGELVVMNMPGADCKRYTPVHMKELVEIWNSIVQREDDLMGFRAAKRDKCNNVLNATAVDHGYMYATTGGTYYNYNTLGDVLNYDKMKWGNGTLWGPAHEFGHNHQQLFNTAGMTEISVNMYSNMVMFTSGRVTSRSENCSYTDVDGKKYDGVCESAVSTYADRFANKKKWFEYGTWGTTQMYYKLYMMFHSTGLDNQFWHKCLDYLRTHRLEGQGTANCQGQNDYLLFAKACSYAAQQDLSSFFEAWGHFYDVNGSVIGDYSNTTMYTTRAQWMEAKKFMQKYPKGPANNMIFIDDHIRRTPATYPGHAAGEMREDFNGAVRVGRMGDFGSWDQFCPDSLGQGYAIIKTQSDANGKRTYTMEAKNSHVVGFKIYNSKGQLIYFANTKTFTIPKKVMEDAKNDIKVKVCGSDGSEVDPGTVPLGITTFSAQANGGKVDVYSIYGVLVRSKVNAETALEGLPNGVYVVGGKKVVVGK
>NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein
MKLKINFLFILSVLFVGTLGLASCATDYDTDFTGKELEVPHSSQRMIAFNKEGGEQQIAVETNVALDEWKAESNADWLTVTKNADGKGVTVKTPAYDGFKAREAKVTISHGERASYEIKVSQMGFESVLRIPEQNPFFNREGTFYSLLESKVTSIDVPVETNLNLDHIIVPDTVSFVRLDASKTVKENGIVKLHFDMDPNTTSEKRYCTVRLKSSDNWDASIEYVIEQAAKGYKVRPIYPVETKQASVEMIDLGRTYRVPFQRTAVDGNYEVIIPDNAKDWLSTTKKFIAGSEVVFTTTLNTTDSPRSCDVVCKPSNGSTQPFTIHVTQQAFQDIVPTGVSELNVTPGKGQFNVSWKAPDEVNYEKVIVRAKSNMPGVPESVKEVAATETSCVLNDVFNFAGNYTITVTTQGLRGKNTDAPATATAQANEWSESVEIPLTAAMVSSNSMQPGHEIGSAVDGNKTTYFQTKSNGSTSDPRPHIDITLNEGINGTFYLAFDENKVTSNDRNPKKANIYASSDVITATTRPLTQTNFRSANAVSEPLSYTKTNGVTVTHIRFEPTQRKNGTNINNGGGSSYWYLAELHLYVYHDEAWKREQLGL
>NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein
MKKYKYILGCALAAVALSSCNNYDFEQNFYPHKVGLMAGTNRIYDRTTVELSTVENGTASVQLVANLSGSQLADRDYHVTIAHDDSLFNAYNKSNFDIDSTKFARLLPQNCYEDPAMAGTIPSGSNKCLFDIKLKNLGTLSPDSTYFLNYKIVSHDASALATDNNKLGVKLDHVLIKVTWKNAYGSTAEGWNYQLVSSQVTNLETKSTTRPTNTVRAFPVAANAVRFLAGDEKWDNYEKALHDINVKSIVATIGSKTVTNPSAYNVTLKPYKQDSLEVEMLTPVGEYNNTFLLNELGGSASTNPTYFKEFRLHYRYRVMKNAKQNDGTWKAGPWKEVLSKLRYQYNPRADKL
>NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKHILALGAVAALFSGMTFTSCNFLDQDDNFNAIFKEDSVFHSAQNANGYLFATPTMFPSAGNIWGNSWTPGETASDEICVRWQTNEFWGAKFTVGNVNAENVPNWGYWYQMYKIINRCNRMLANVDKIGDMSNNDKADYKAMVHFIRGYAYYVLLQNWGPCLIVNDEVISTSEKADYYDRERATMDESIDYICNEFAQSLPGLKRPSEQSTAYFGRPTKGTALALIARLRLLQASPTFNGGTYAKRCFGEWKRKSDGKYYVNQDYDAKRWAVAAAAAKQVIDLNYYTLFTVDADKDNPYPLDASVPTAKFPDGAGGIDPYHSFADMFNGEGTAKVNREFIWADEYSGPVMNYSRHSFPVNYGGWGGMSVPQRVIDCFLMKDGKKPAESPLYEADLTKHVNQKKSIGDCDMANGTPLAYTNRSARFYASIGFPGRIWKMNSTTDGSYNNQTFWYSIDDSKAGKNAAGNNPNDYCISGYVPFKYIHPDDSWHGKDGASVIPKPFPIIRYAEILLIYCEAANHIQGSETVKTWDVSGRLVDVAVTRDEAAMARYFNMIRYRVGLPGVEAATLSSENAFDEVIKNERQVELFNEGYRYFDTRRWGTYFTEDANSSNWRGLDVYSEKKGNNDGPFFNLVTINEQNIRDRKALPRMVFLPLMHRELLKSPKMDQNPGWDR
>NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor
MRRTLYVLCLMVALLTYGLQAYSQDNSTAKQFSVAGVILDDTGEPCIGATVRVKNEPGVGTISDLDGKFNIKVKPGATLLFEYVGMETVQRTILKDEPSLSVKFKVAKTNAIDEVVVTGLVSQKKVSVVGAVSTINMDELRTPGTSLVNMIGGRMPGVITMQTSGEPGQNLSNFWVRGVSTFGAGAGALVLIDGIEGRLNDIDVDDVESISVLKDAAATAVYGVRGANGVVLVTTKRGSKEKIQVTARATVKLSQIKRLPEYLSSYDYARLANEARAMSGESDLYTPIQLDIIKNNLDPELYPNVNWIDQIMKKTSLQENYYASARGGGDVAQYFVSVGYRHEGAAYKQKENQFHRPLSYDQLTYRANINMNLTKRSELYFGVDGNISNYTTPGGKNTNQVWSDVLQLNPLMFPVTYADGTLPTYGQSDLISPFAALNYQGYKSSDYSRNMITLKFTHRFGGILKGLVGSVQAVNDRTAGFSERRFVRPDYYRATGRTSTGDLIKTLRSKQQDMSYSSDNESWRKYYMEAKLDYNTSFGAHNLGALLFYYMEDTKGSEWGNGDALGIAAIPKRRQNVSGRLSWGYNSTYFVDANFGYTGSDLFPKGQRFGFFPSIAVGWAPTSYKWVQKHLPFVNFFKIRGSYGLAGNDNIANTRFPYLTIINNHAGTTWGYNGSGIVEKQQGADNLKWEVAKKLNVGIDANFFNDAIKLNVDFFRDTRDHIFQDRVTLPEFAGMVTYPKSNVGRMHSFGSDGNISYFHKINKEMNFTVRANYTWSQNIVDYFEENKLAYDYQSVTGMPYGVLRGYIAEGLFKDEADIRQSADQTAAFGVVRPGDIKYRDVNGDGVINKDDRVPLSYGNNVPRVMFGIGGEFNYKDFTVSMLFKGNTGVNYYRVGMGYDAGWIPFYNGEMGNVLKMVNNPKNRWIPSWYSGDPSTENPNAMFPRLSYGSNANNSQLSTFWKKNGSFLRFQELNFRYVFRHRKWLRAAGLSALECDFVINNLFTIDSAKYFDPEQAWFNGAAYPIPTTYSLQMYFRF
>NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein
MKRLFKSYLWMVLMGSLAWVSCSDKEVGGTAGTAFDPSQPIVISDFYPDSGGIATPMIITGKNFGTDTTGLALWYVDEDGRRHRGGLVSSNGEKLYCYVPAGLTYKRNIKLEVTRANGTDTIKGAGDRDFKYITQTAVTTIVGTQTSDAHATKIDKLLTSNLSAPGYLCVDNENNIFIVQHRFDDSFVANGSNSFIECRNEKNENVGGMVLKADLKRDQLSILQVNSNTKEKINAPAYSTLDGYEGVYVPDDSGRKYYSLLKDQGYAVHKQQFINPNGYANLDQSNWKYCFVINKNDQMIYSVMFKGQLIRINPKTRKAELLLKRVGKDGPKGDGGSDTFCTFSPTQPNRLFISFTDAHQIWYVDVDQLLDKDSLTYQGEPYAGISSFGTVNVTEGKGWEDGALKNAKFCYPRQMTFTKDGKLYIADSGNHCIRMIDTTLGKNARVTTPIGVPQSAGFQDGGVELAKFNWPTGVAVSADGSTVYVADSKNQVIRELSIK
>NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein
MKNNMKKNILATCGLLFCTSLLHAQTTEEVRIDFENQNYKALGVYDTWLKSPFRSQNKQAAVLEGNVQVVSNIDKNYDEILKATPNASDNVLGFQRSRFGSNTFGARIDLKQPFALTKETKYVHVMIHKAKVGRTMLIGLGKRTDRAGQSVDTEQFWELSTREVEPNKWVDAVFPVKGAGGIEIHSLVVVVDCEDTNGLKDDFLAYIDNIVVNNEAFTTTNREDYPMNYNKDAKCSRTDRGLKGISLGDQTFNVYGDITTSIPAYTYLSKQAFLAKPGETLNPAVQYKGIWMHSYVYLDLNNNGRFEPKVEGGQIVPNAGNELLAYSFLGGEDENSGFNSAGTEISGNGRNTLVMPEFTLPSDLQHGFYRMRYKVDWNSADAGGSIENNNHILNNGGGAIDVRLNVHGDNVKIYQGALNGKVVAEDGTELNGISIPFGKPYTIKMKPEHGFNFSGLKVRHGYNLTGDSISHGTYQYVDELIPRERFNADGTFTLPAEMIDGDVSLEGIFIDAKTALTYEVYFNNEFVYSTVVNGAKTGAVTIPEGLSRDYVELIADKQTITSLPATVRINATWTAPMKVATPTDTTWYNLKVSNQPRWVSSGNYTPNVYFIDETYITTDYALWALTGNPYSGFRLINKAMGPTMVLASASPKGSAKAGGNTYATLLPADNLPAGYTSDWTVTISPNDDEGFYICNPEGFGLNYRADGNLAYWTGGKDAGSTFVPTEVKKTSTGINALIFKNESATTYDLSGKAVSKSHKGVVIRNGKKMLVK
>NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase
MNNRFLHGVLTALALTASATSFAQTNTVMTLKTQIAPNAENEPRPVFPVPTDRQWKWQQTEFYAFFHYGMNTYTNKEWGNGDEDVNTFAPTAKPDPRQWLEAVKEAGMTGGIAVVKHHDGFCLWPTETTDHKSSNSSSPNAQVNIAELFAKAAQDLKMKYGFYVSPWDRNSGLYGTDSYVKDVFLKQCAELAKYGSDQFEMWFDGANGGNGYYGGKNKTINIDRATYYDVPNLRDSIHKLSPNIILWGVGGEARWIGNEDGWAGETNWCNENRGFAPERNGMYGTENGWFWLPGESDAKFTDKGWFWHPGCEPMSAERTFQMYLETVGRNATLILNCPPDRSGRIPQNQVSRLKEFGTMLKSRFKTNLAKTATLEATNTRANGATRTYVVNNLIDENPDTYWAAEDDVKDVTLTFKWNSPQTVRYVTLQEYVRLGQRVKSFSIEYTTDGSTWKPLANKVKQTTIGYKRIIPLNGSTANSYGSGYDAKAIRIHIKDAKACPVMSEIAIY
>NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein
MKKKKAKILLAALLLAVGETAFADGKAVSGIRQINPTTVEITYSDGGVMTVDFYGQNVFRLFRDPKGGIVRDPVSNPPARILLDNPRKNAGRLSVNETDADVAVATAEVRVRFDRNTGLMTVTDLRNGKEVIKEVKGVDFQKNRTTVTLANAAGEYFYGGGVQNGRFSHRGKRIEIVNTNSWTDGGVASPAPFYWSTGGYAAMPYTFAPGAYDFGSTDKNTVTISHEMPYLDLFLMVDTTPVSLLQDYYQLTGNPVLLPKFAFYEGHLNAYNRDYWKETTEEGKGILFEDGKRYVESQKDNGGIKESLNGEKQNYQFSARAVIDRYKKDDMPLGWILPNDGYGAGYGQTSTLDGNIANLKSLGDYARKQGVEIGLWTQSNLHPVDSIPALLQRDIVKEVRDAGVRVLKTDVAWVGAGYSFGLNGIADVANIMPYYGSDARPFIITLDGWAGTQRYGGVWSGDQTGGEWEYIRFHIPTYIGSGLSGMGNITSDMDGIFGGKNLSVNIRDFQWKTFTPMQLNMDGWGSNPKYPQALGEPATSINRSYLKLKSMLLPYTYSCAHEAVTGKPLMRAMFLDDSNDYTHSSATRYQYMYGPSFLVAPIYQNTAADKEGNDVRNGIYLPKGTWYDYFTGATYEGGCVLNDYFAPIWKLPVLVKSGAIIPMVNANNNPSEIDKNRRVFELYPDGKTEFTLYDDDGTTQKYLSNEKATTRITSDLNDKQVLTVSIDKTEGTFDGMVKNQSTTFYLNTNAKPKKLTAVIGGKKIRLTEAEQGDNTWQYVQASNINRFSTTNSEMERLLVTKNAQIIVRLASCDITKEAVELRVEGFARLNKSNETLRKKGALTAPELLEADVQSYSVTPKWKPVQNADYYEIAFNGQTYTTIRHNSLLFDDLQPATDYDFKVRAVNSEGASEWMPLHVKTAVNPLEYAIQGLTATSTARDMEGFEIHRLVDFSTTGDIWHTYYYTKAVPFDFTVDLHSTNTLDKLQYVPRANGGNGTITKCDIAVSKDGRNWTEIGPQQWARDGRTKEVTLSTHPVARYVKVSVKEAVGNFGSGREFYVFKVPGTKTILPGDINLDGKVDENDFTSYMNYTGLKKGDADFDGYISGGDINGNGLIDAYDISNVAMHLEDGWNDDDVAPVGGKVYYEYNRKSYAAGDDVIIKVKGKDLQSVNAFNLIFPYSPKELQFVKVETDPSMVMRNLTYDRHHSDGSQVLYPTFVNVGDHHTFNGDADLLVIRMKALKPFTVKPQTAKGLLVDKQLEEVELK
>NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin
MKKKFICTVCGYIHEGTEAPAECPVCHAKAAKFKEFNPEALKGTKTEQNLKNAFAGESQAHTKYLYYASKAKKDGYEQIAGFFEETARNEKEHAKIWFKFLHEGDIPTTTVNLADAAAGENYEWTDMYEQMAKDAMEEGFPELAVKFRSVGKVEKHHEERYRKLLKNIEDSVVFSREGDCIWQCRNCGHIVIGKKAPAVCPVCNHPQSFFQVEESNY

Crispr_ID: NZ_CP054010_5

• CRISPR_ID: NZ_CP054010_5
• CRISPR_location: 892085-892203
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_5

Consensus_repeat	Method
CAAAGAGAGACAGAGTAACATAAGAACAAGG	CRISPRCasFinder

spacers of NZ_CP054010_5

>5.1|892116|57|NZ_CP054010|CRISPRCasFinder
GGGTTCCTTTATAACAAGCAACTTGTTTACTCGTAAACTCGTCTAACTCGTCAACTA

CRISPR arrays and Neighbor proteins around NZ_CP054010_5

CRISPR arrays

The CRISPR arrays of NZ_CP054010_5

>merge|NZ_CP054010|5|892085-892203|CRISPRCasFinder
CAAAGAGAGACAGAGTAACATAAGAACAAGGGGGTTCCTTTATAACAAGCAACTTGTTTACTCGTAAACTCGTCTAACTCGTCAACTACAAAGAGAGACAAAGTAACATAAGAACAAGG

>NZ_CP054010|5|5|892085-892203|CRISPRCasFinder
CAAAGAGAGACAGAGTAACATAAGAACAAGG	GGGTTCCTTTATAACAAGCAACTTGTTTACTCGTAAACTCGTCTAACTCGTCAACTA
CAAAGAGAGACAAAGTAACATAAGAACAAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	unknown	unknown	gnl|CDD|379719
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|269882
NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein	unknown	unknown	gnl|CDD|372921
NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	unknown	unknown	gnl|CDD|271323
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	unknown	unknown	gnl|CDD|367917
NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|236992
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	unknown	unknown	gnl|CDD|226195
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	unknown	unknown	gnl|CDD|372993
NZ_CP054010.1|WP_036885798.1|903849_904281_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	unknown	unknown	gnl|CDD|379166
NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein	unknown	unknown	gnl|CDD|275342
NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|373012
NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	unknown	unknown	gnl|CDD|153100

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	gnl|CDD|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.18595e-10
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	gnl|CDD|269882	cd06596, GH31_CPE1046, Clostridium CPE1046-like. CPE1046 is an uncharacterized Clostridium perfringens protein with a glycosyl hydrolase family 31 (GH31) domain. The domain architecture of CPE1046 and its orthologs includes a C-terminal fibronectin type 3 (FN3) domain and a coagulation factor 5/8 type C domain in addition to the GH31 domain. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.	0
NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein	gnl|CDD|372921	pfam14135, DUF4302, Domain of unknown function (DUF4302). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 344 and 443 amino acids in length. There are two completely conserved residues (R and L) that may be functionally important.	1.5085e-57
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	gnl|CDD|271323	cd14953, NHL_like_1, Uncharacterized NHL-repeat domain in bacterial proteins. This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	9.68928e-20
NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein	gnl|CDD|367917	pfam04383, KilA-N, KilA-N domain. The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.	1.20438e-11
NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	4.29635e-07
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.42649e-43
NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA	gnl|CDD|236992	PRK11819, PRK11819, putative ABC transporter ATP-binding protein; Reviewed.	0
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	gnl|CDD|226195	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism].	4.61922e-33
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	1.61174e-12
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	gnl|CDD|372993	pfam14274, DUF4361, Domain of unknown function (DUF4361).	6.672e-15
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	6.0924e-58
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	gnl|CDD|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	2.76184e-33
NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	3.3025e-179
NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|373012	pfam14322, SusD-like_3, Starch-binding associating with outer membrane. SusD is a secreted polysaccharide-binding protein with an N-terminal lipid moiety that allows it to associate with the outer membrane. SusD probably mediates xyloglucan-binding prior to xyloglucan transport in the periplasm for degradation. This domain is found N-terminal to pfam07980.	2.11185e-24
NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein	gnl|CDD|275342	TIGR04549, LP_HExxH_w_tonB, substrate import-associated zinc metallohydrolase lipoprotein. Members of this family are lipoproteins with the typical zinc metallohydrolase HExxH motif and additional similarities to a better-documented zinc peptidase family, pfam06167. The seed alignment begins immediately after the lipoprotein motif Cys residue. Up to five members of this protein family occur per genome, in the context of certain gene pairs related to RagA and RagB, or to SusC and SusD. Those gene pairs, like the present family, are restricted to the Bacteriodetes, may number up to 100 pairs per genome, and are linked to TonB-dependent uptake of biopolymer-derived nutrients such as glycans. A possible function for this lipoprotein is to hydrolyse larger molecules to prepare substrates for import and utilization. [Unknown function, Enzymes of unknown specificity].	1.9574e-130

Protein sequences

>NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein
MKRLFKSYLWMVLMGSLAWVSCSDKEVGGTAGTAFDPSQPIVISDFYPDSGGIATPMIITGKNFGTDTTGLALWYVDEDGRRHRGGLVSSNGEKLYCYVPAGLTYKRNIKLEVTRANGTDTIKGAGDRDFKYITQTAVTTIVGTQTSDAHATKIDKLLTSNLSAPGYLCVDNENNIFIVQHRFDDSFVANGSNSFIECRNEKNENVGGMVLKADLKRDQLSILQVNSNTKEKINAPAYSTLDGYEGVYVPDDSGRKYYSLLKDQGYAVHKQQFINPNGYANLDQSNWKYCFVINKNDQMIYSVMFKGQLIRINPKTRKAELLLKRVGKDGPKGDGGSDTFCTFSPTQPNRLFISFTDAHQIWYVDVDQLLDKDSLTYQGEPYAGISSFGTVNVTEGKGWEDGALKNAKFCYPRQMTFTKDGKLYIADSGNHCIRMIDTTLGKNARVTTPIGVPQSAGFQDGGVELAKFNWPTGVAVSADGSTVYVADSKNQVIRELSIK
>NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor
MRRTLYVLCLMVALLTYGLQAYSQDNSTAKQFSVAGVILDDTGEPCIGATVRVKNEPGVGTISDLDGKFNIKVKPGATLLFEYVGMETVQRTILKDEPSLSVKFKVAKTNAIDEVVVTGLVSQKKVSVVGAVSTINMDELRTPGTSLVNMIGGRMPGVITMQTSGEPGQNLSNFWVRGVSTFGAGAGALVLIDGIEGRLNDIDVDDVESISVLKDAAATAVYGVRGANGVVLVTTKRGSKEKIQVTARATVKLSQIKRLPEYLSSYDYARLANEARAMSGESDLYTPIQLDIIKNNLDPELYPNVNWIDQIMKKTSLQENYYASARGGGDVAQYFVSVGYRHEGAAYKQKENQFHRPLSYDQLTYRANINMNLTKRSELYFGVDGNISNYTTPGGKNTNQVWSDVLQLNPLMFPVTYADGTLPTYGQSDLISPFAALNYQGYKSSDYSRNMITLKFTHRFGGILKGLVGSVQAVNDRTAGFSERRFVRPDYYRATGRTSTGDLIKTLRSKQQDMSYSSDNESWRKYYMEAKLDYNTSFGAHNLGALLFYYMEDTKGSEWGNGDALGIAAIPKRRQNVSGRLSWGYNSTYFVDANFGYTGSDLFPKGQRFGFFPSIAVGWAPTSYKWVQKHLPFVNFFKIRGSYGLAGNDNIANTRFPYLTIINNHAGTTWGYNGSGIVEKQQGADNLKWEVAKKLNVGIDANFFNDAIKLNVDFFRDTRDHIFQDRVTLPEFAGMVTYPKSNVGRMHSFGSDGNISYFHKINKEMNFTVRANYTWSQNIVDYFEENKLAYDYQSVTGMPYGVLRGYIAEGLFKDEADIRQSADQTAAFGVVRPGDIKYRDVNGDGVINKDDRVPLSYGNNVPRVMFGIGGEFNYKDFTVSMLFKGNTGVNYYRVGMGYDAGWIPFYNGEMGNVLKMVNNPKNRWIPSWYSGDPSTENPNAMFPRLSYGSNANNSQLSTFWKKNGSFLRFQELNFRYVFRHRKWLRAAGLSALECDFVINNLFTIDSAKYFDPEQAWFNGAAYPIPTTYSLQMYFRF
>NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKHILALGAVAALFSGMTFTSCNFLDQDDNFNAIFKEDSVFHSAQNANGYLFATPTMFPSAGNIWGNSWTPGETASDEICVRWQTNEFWGAKFTVGNVNAENVPNWGYWYQMYKIINRCNRMLANVDKIGDMSNNDKADYKAMVHFIRGYAYYVLLQNWGPCLIVNDEVISTSEKADYYDRERATMDESIDYICNEFAQSLPGLKRPSEQSTAYFGRPTKGTALALIARLRLLQASPTFNGGTYAKRCFGEWKRKSDGKYYVNQDYDAKRWAVAAAAAKQVIDLNYYTLFTVDADKDNPYPLDASVPTAKFPDGAGGIDPYHSFADMFNGEGTAKVNREFIWADEYSGPVMNYSRHSFPVNYGGWGGMSVPQRVIDCFLMKDGKKPAESPLYEADLTKHVNQKKSIGDCDMANGTPLAYTNRSARFYASIGFPGRIWKMNSTTDGSYNNQTFWYSIDDSKAGKNAAGNNPNDYCISGYVPFKYIHPDDSWHGKDGASVIPKPFPIIRYAEILLIYCEAANHIQGSETVKTWDVSGRLVDVAVTRDEAAMARYFNMIRYRVGLPGVEAATLSSENAFDEVIKNERQVELFNEGYRYFDTRRWGTYFTEDANSSNWRGLDVYSEKKGNNDGPFFNLVTINEQNIRDRKALPRMVFLPLMHRELLKSPKMDQNPGWDR
>NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein
MKKYKYILGCALAAVALSSCNNYDFEQNFYPHKVGLMAGTNRIYDRTTVELSTVENGTASVQLVANLSGSQLADRDYHVTIAHDDSLFNAYNKSNFDIDSTKFARLLPQNCYEDPAMAGTIPSGSNKCLFDIKLKNLGTLSPDSTYFLNYKIVSHDASALATDNNKLGVKLDHVLIKVTWKNAYGSTAEGWNYQLVSSQVTNLETKSTTRPTNTVRAFPVAANAVRFLAGDEKWDNYEKALHDINVKSIVATIGSKTVTNPSAYNVTLKPYKQDSLEVEMLTPVGEYNNTFLLNELGGSASTNPTYFKEFRLHYRYRVMKNAKQNDGTWKAGPWKEVLSKLRYQYNPRADKL
>NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein
MKLKINFLFILSVLFVGTLGLASCATDYDTDFTGKELEVPHSSQRMIAFNKEGGEQQIAVETNVALDEWKAESNADWLTVTKNADGKGVTVKTPAYDGFKAREAKVTISHGERASYEIKVSQMGFESVLRIPEQNPFFNREGTFYSLLESKVTSIDVPVETNLNLDHIIVPDTVSFVRLDASKTVKENGIVKLHFDMDPNTTSEKRYCTVRLKSSDNWDASIEYVIEQAAKGYKVRPIYPVETKQASVEMIDLGRTYRVPFQRTAVDGNYEVIIPDNAKDWLSTTKKFIAGSEVVFTTTLNTTDSPRSCDVVCKPSNGSTQPFTIHVTQQAFQDIVPTGVSELNVTPGKGQFNVSWKAPDEVNYEKVIVRAKSNMPGVPESVKEVAATETSCVLNDVFNFAGNYTITVTTQGLRGKNTDAPATATAQANEWSESVEIPLTAAMVSSNSMQPGHEIGSAVDGNKTTYFQTKSNGSTSDPRPHIDITLNEGINGTFYLAFDENKVTSNDRNPKKANIYASSDVITATTRPLTQTNFRSANAVSEPLSYTKTNGVTVTHIRFEPTQRKNGTNINNGGGSSYWYLAELHLYVYHDEAWKREQLGL
>NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein
MLFERFLRKKTLMAALALTAAVPSVAKASMLSAAPTADGENQKLKPGVYYIVNDKRQKGTDLHVFVNDEGTLHGQHYGSPSTDFSDLFLLRAKDGRYTIQSLKNAKYVQSVGQNNEVYKTANDAYKFRIIYQTESSGTGKSYFNIYNSNAEDWCWHIDAQKNIVRWKPLMDNGIRAVGPSEFRFDPVTTLTNEQVLARLAQLTKVVDPTKDLTKYYQIVSDTYGRSMREDFIVGELSTSGFNSSDYSYYWKLERLANGRYVFQNAVTGKYIVPQNGQTSRSYTTAEGKGTGFDLQRNTDDPYGLAFEMVDANNVGIHCAESQGYHPVGWYTHNEANKWVFKEATLDPAKLKEQQEAYKARVDLTKNVDVYAEKVAKYFTNSAATEVTAATKAMTDEALKAQMTTEGVPQGLQEVVLKIKNQSWTAYPSGRNWEKLFRIADYKVYSENNYNAWARSMGIGYDYGSMTNPTGITARDGEDLFVFLGDDIPQNATVQIELVPLGTRSAGKYYSLKKGLNIILNQGENNVFVNYIGRTFNNGKYLRDYKPMNIHIEGGKVNGYFDLTKGNTNEDWQKMQSDGLVWAKAFNMKGELVVMNMPGADCKRYTPVHMKELVEIWNSIVQREDDLMGFRAAKRDKCNNVLNATAVDHGYMYATTGGTYYNYNTLGDVLNYDKMKWGNGTLWGPAHEFGHNHQQLFNTAGMTEISVNMYSNMVMFTSGRVTSRSENCSYTDVDGKKYDGVCESAVSTYADRFANKKKWFEYGTWGTTQMYYKLYMMFHSTGLDNQFWHKCLDYLRTHRLEGQGTANCQGQNDYLLFAKACSYAAQQDLSSFFEAWGHFYDVNGSVIGDYSNTTMYTTRAQWMEAKKFMQKYPKGPANNMIFIDDHIRRTPATYPGHAAGEMREDFNGAVRVGRMGDFGSWDQFCPDSLGQGYAIIKTQSDANGKRTYTMEAKNSHVVGFKIYNSKGQLIYFANTKTFTIPKKVMEDAKNDIKVKVCGSDGSEVDPGTVPLGITTFSAQANGGKVDVYSIYGVLVRSKVNAETALEGLPNGVYVVGGKKVVVGK
>NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein
MKRLQLIVPMLACCLALPCLSFTDVKDSYLVLQVDTTQKYEQYSYVNEKGETVVPSNRYLLCYTDTIRTIGFVLKPNVGCVAINTQGQELFNVYMVDNGNDYPVNGLFRILDESGQKMGVANMEGKVIVNPKYDAIFPYHDGLAAVAVGSKTVRPADDPEHEYTVGGKWGFIDKQGNEVIPLEYDSIANYRRFVNGKALVLKHGKWIKLSIRQKKR
>NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein
MFVLFFLCFSIYGKAQTAPKKLTAPSPERFQAINDSILAEGMWLYTYEKLAWRATDSLMKYNVKREEINSATAFEEGNLTWRYIFANLDKEQTVFELTLHLSNDTSFYVCSATPRKLKPTEIEQLKAKQIAPRKVIKEKGDSIFLSNTSGLNWDLIPLTNGCYRLYLLHGTTKHGVIPIGDDYAFDFDKDMNILSWRRFHRSFLEQPITMNGEKITEVMHSHTPMTPYFTTTDIANYMLYGCDLYGIKRFSVLSTAFADTSYLTTFDVEKMKLTSTVYTVK
>NZ_CP054010.1|WP_004359206.1|874351_876049_+|energy-dependent-translational-throttle-protein-EttA
MATVDDKKIIFSMVGVSKIIPQNQKQILKNIYLSFFYGAKIGIIGLNGAGKSTLMKIIAGLVEPTQGEVVWSPGYSVGYLPQDPPLDEAKTVKENVMEGVQHIYDALKEYDDINVKFGLEEYYSDADKMDKLMQRQAELQDIIDATDAWNIDSRLERAMDALRCPKGDLPVTNLSGGERRRVALCRLLLQKPDVLLLDEPTNHLDAESIDWLEQHLQQYEGTVIAVTHDRYFLDDVSEWILELDRGEGIPWKGNYSSWLDQKTKRMEQEEKSASKRRKTLERELEWVRMAPKARQAKGKARLNSYEQMLNEEQKQREEKLEIFIPNGPRLGNKVIEAQHVKKAFGEKVLFNDLNFMLPPNGIVGVIGPNGAGKTTLFRLIMGLEQADGGTFEVGETVKLAYVDQQHKDINPNKTVYDVVSQGNETIRMGGRDINSRAYLSRFNFSGTDQSKLCSVLSGGERNRLQLAMALKQEGNVLLLDEPTNDIDVNTLRALEEGLEAFAGCAVVISHDRWFLDRICTHILAFEGNGEVVYFEGGFSDYEINKARRLGNEEIKKGRYRKLMEE
>NZ_CP054010.1|WP_004359207.1|873262_874081_+|KilA-N-domain-containing-protein
MTKKGEIFVKDVAIKTMTKDGIDYICITDIARQKNAAEPKDVVKNWMRQKNTLEYLGLWEKLNNPNFKGVEFDPLLAEAGSNSFTMSPTRWVELTAAIGVFTKNGAGGGTFAQRDIAFKFANWVSVEFELYLVMEFQRLKAKEQELIGWTAKRELSKINYRIHTDAIKSHLIPEKVTPTQANIIYAEEADVLNVAMFGMTARQWRESNPDLKGNIRDYASVNELICLSNMENINAVLINDDIPQGERLVRLNQIAIHQMQILERNSNRNLLR
>NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein
MKNNMKKNILATCGLLFCTSLLHAQTTEEVRIDFENQNYKALGVYDTWLKSPFRSQNKQAAVLEGNVQVVSNIDKNYDEILKATPNASDNVLGFQRSRFGSNTFGARIDLKQPFALTKETKYVHVMIHKAKVGRTMLIGLGKRTDRAGQSVDTEQFWELSTREVEPNKWVDAVFPVKGAGGIEIHSLVVVVDCEDTNGLKDDFLAYIDNIVVNNEAFTTTNREDYPMNYNKDAKCSRTDRGLKGISLGDQTFNVYGDITTSIPAYTYLSKQAFLAKPGETLNPAVQYKGIWMHSYVYLDLNNNGRFEPKVEGGQIVPNAGNELLAYSFLGGEDENSGFNSAGTEISGNGRNTLVMPEFTLPSDLQHGFYRMRYKVDWNSADAGGSIENNNHILNNGGGAIDVRLNVHGDNVKIYQGALNGKVVAEDGTELNGISIPFGKPYTIKMKPEHGFNFSGLKVRHGYNLTGDSISHGTYQYVDELIPRERFNADGTFTLPAEMIDGDVSLEGIFIDAKTALTYEVYFNNEFVYSTVVNGAKTGAVTIPEGLSRDYVELIADKQTITSLPATVRINATWTAPMKVATPTDTTWYNLKVSNQPRWVSSGNYTPNVYFIDETYITTDYALWALTGNPYSGFRLINKAMGPTMVLASASPKGSAKAGGNTYATLLPADNLPAGYTSDWTVTISPNDDEGFYICNPEGFGLNYRADGNLAYWTGGKDAGSTFVPTEVKKTSTGINALIFKNESATTYDLSGKAVSKSHKGVVIRNGKKMLVK
>NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase
MNNRFLHGVLTALALTASATSFAQTNTVMTLKTQIAPNAENEPRPVFPVPTDRQWKWQQTEFYAFFHYGMNTYTNKEWGNGDEDVNTFAPTAKPDPRQWLEAVKEAGMTGGIAVVKHHDGFCLWPTETTDHKSSNSSSPNAQVNIAELFAKAAQDLKMKYGFYVSPWDRNSGLYGTDSYVKDVFLKQCAELAKYGSDQFEMWFDGANGGNGYYGGKNKTINIDRATYYDVPNLRDSIHKLSPNIILWGVGGEARWIGNEDGWAGETNWCNENRGFAPERNGMYGTENGWFWLPGESDAKFTDKGWFWHPGCEPMSAERTFQMYLETVGRNATLILNCPPDRSGRIPQNQVSRLKEFGTMLKSRFKTNLAKTATLEATNTRANGATRTYVVNNLIDENPDTYWAAEDDVKDVTLTFKWNSPQTVRYVTLQEYVRLGQRVKSFSIEYTTDGSTWKPLANKVKQTTIGYKRIIPLNGSTANSYGSGYDAKAIRIHIKDAKACPVMSEIAIY
>NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein
MKKKKAKILLAALLLAVGETAFADGKAVSGIRQINPTTVEITYSDGGVMTVDFYGQNVFRLFRDPKGGIVRDPVSNPPARILLDNPRKNAGRLSVNETDADVAVATAEVRVRFDRNTGLMTVTDLRNGKEVIKEVKGVDFQKNRTTVTLANAAGEYFYGGGVQNGRFSHRGKRIEIVNTNSWTDGGVASPAPFYWSTGGYAAMPYTFAPGAYDFGSTDKNTVTISHEMPYLDLFLMVDTTPVSLLQDYYQLTGNPVLLPKFAFYEGHLNAYNRDYWKETTEEGKGILFEDGKRYVESQKDNGGIKESLNGEKQNYQFSARAVIDRYKKDDMPLGWILPNDGYGAGYGQTSTLDGNIANLKSLGDYARKQGVEIGLWTQSNLHPVDSIPALLQRDIVKEVRDAGVRVLKTDVAWVGAGYSFGLNGIADVANIMPYYGSDARPFIITLDGWAGTQRYGGVWSGDQTGGEWEYIRFHIPTYIGSGLSGMGNITSDMDGIFGGKNLSVNIRDFQWKTFTPMQLNMDGWGSNPKYPQALGEPATSINRSYLKLKSMLLPYTYSCAHEAVTGKPLMRAMFLDDSNDYTHSSATRYQYMYGPSFLVAPIYQNTAADKEGNDVRNGIYLPKGTWYDYFTGATYEGGCVLNDYFAPIWKLPVLVKSGAIIPMVNANNNPSEIDKNRRVFELYPDGKTEFTLYDDDGTTQKYLSNEKATTRITSDLNDKQVLTVSIDKTEGTFDGMVKNQSTTFYLNTNAKPKKLTAVIGGKKIRLTEAEQGDNTWQYVQASNINRFSTTNSEMERLLVTKNAQIIVRLASCDITKEAVELRVEGFARLNKSNETLRKKGALTAPELLEADVQSYSVTPKWKPVQNADYYEIAFNGQTYTTIRHNSLLFDDLQPATDYDFKVRAVNSEGASEWMPLHVKTAVNPLEYAIQGLTATSTARDMEGFEIHRLVDFSTTGDIWHTYYYTKAVPFDFTVDLHSTNTLDKLQYVPRANGGNGTITKCDIAVSKDGRNWTEIGPQQWARDGRTKEVTLSTHPVARYVKVSVKEAVGNFGSGREFYVFKVPGTKTILPGDINLDGKVDENDFTSYMNYTGLKKGDADFDGYISGGDINGNGLIDAYDISNVAMHLEDGWNDDDVAPVGGKVYYEYNRKSYAAGDDVIIKVKGKDLQSVNAFNLIFPYSPKELQFVKVETDPSMVMRNLTYDRHHSDGSQVLYPTFVNVGDHHTFNGDADLLVIRMKALKPFTVKPQTAKGLLVDKQLEEVELK
>NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin
MKKKFICTVCGYIHEGTEAPAECPVCHAKAAKFKEFNPEALKGTKTEQNLKNAFAGESQAHTKYLYYASKAKKDGYEQIAGFFEETARNEKEHAKIWFKFLHEGDIPTTTVNLADAAAGENYEWTDMYEQMAKDAMEEGFPELAVKFRSVGKVEKHHEERYRKLLKNIEDSVVFSREGDCIWQCRNCGHIVIGKKAPAVCPVCNHPQSFFQVEESNY
>NZ_CP054010.1|WP_036885798.1|903849_904281_+|hypothetical-protein
MNTLKISIITCFSILYSLTSFAEVKSNVSIEIGSFDSIPSEIDGGCCVFYKYPNKMRNKSYIMVNDLATTAYMVINRRLEEFTLVSNWKDVFWYKNKRFTLKVTINHTQSKGDNEFYKVKGILIVEDRNKNQQKLSFCGNCSW
>NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein
MKKYISIFLLVAAAVLGTACSNDNNELPEYAAGLNVVKAQTAFNVIGGTNMVKMASEPAQAYAQDAWLTVTKKAETLELTATTNTSPQSRNTLLVIKNLQGDSITLNVQQEGVTFGLPAGEDIFTDDKAIQKTLIATANVPVTYVTTGDWITVEQKGNEVGVKVAENTTGKARVGWVIAKAVGLVDSLKVVQASLSDFVGEYKQTAKMRNADRTLSKKISDVRIEAMGTNKANFIVDNKYTWAVDFIPGKGFKMTNGKVVAKNEVQTGVYEYFISVIVADDFSKEHETAINGTQESILLAIDDAGNLVFKEAQKLASEQTFSSYGWNRFSDTKPVMGAYRGIGEVYVQPKLTRK
>NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein
MKKVYLLFMAIVLTLSLQSCLHDDKTTFDLPAAERIEKKVADYKALLESSEDGWVMQYYTGKNYSYGGYTLLLKFKNGHVTAMGDVKDVEAKATSGYGVVKDLGPTLSFNEYNAVIHPLAETWLGSPDGAQGDYEFSILRATNDSIFVRGRKWHNDMVLTRLPKGTNWEEYMLGLVTVMEGMNVETYDFVLGNDTLGQGTLTQEVRRLTVTLGDKKWEMPYCTTNTGIVLREPIVIGNKKYQRFTWNDGDHSLTQDDLKIIQFLPKSHKSIDFWVGEWQLKTNLRKRIRLTLEKGSVANTLKGKLNINNINYEILLTYDPATGHLEFPGQPVTDPTYKYPAGIVMIPASQKEGKLFGEGKGSLFFTWDEDMQRAKAEDSGQITGHAVDSFFGVAYGEDLQPVTDAQGNYVFAFTLPNIQYMTKIN
>NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein
MKKYLYLVTIALVSCCAVLSSCSDDKISGDSIFSTKAVERNAFDQWLYKNYTMPYNIDFQYRLKTEETEQAYNFVPADSAKTVKLAILTKYMWFDAYAETVGLDFIKENAPRIILVTGTPGYTRYRTEVIGSAEGGYKVRLGKVNALTDEQLKDYGSMNNYYFHTMHHEFMHILNQKKPYDESYDNISRSDYVSGNWTSIPDKKAQSMGFVSAYSMENPAEDIAELYSIYVTSTPEDWATIMKNAGNKGGTIINKKLKIIREYMSNSWNVDIELLRNAILRRGGKIGTLDLNTLE
>NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKVKKYIIYLPVAAISLALTSCNDFLNKYPDSRMDLKNPTEVSQLLVSAYPQAHPAYLTEMYSDNTDEQLHSTWSAFDRFQEQAYQWKDIDDVSNTETPYQLWSAHYAAISACNEAIEYIEHTVKDAQSEEDYRAQLGEALLCRAFSMFQLSTVFCQAYDKTTAANQLGLPYPTEPEKVVGRLIERGTLAELYQKIEADMLKGIALVGTKYAKPKFHFTKQATYAFATRFYLYAQKYDKAVKYANMVLGDQPADILRNWAEWNRLGPSGNVQPNAFVNASNNANIMLLPVPSQWGVISIPIQAGSKYAHGELISKNETLQAPGPWGDSGSTLNYTVLYNNGVSKYCLRKIPYVPKVIDATAEIGVPYGEYAVFSTDITLLERAEAYALLGQYDKALKDINTELTVFSKNRKQLTLADIQDFYGSMAYYTPTKPTPKKKLNPLFTVEATTQEPLLQCLLQLKRLVTIHEGFRLQDVKRYGITMYRRKVDVQSNVTAVTDSMKVGDPRLAIQLPQDVITAGVKPNPRNN
>NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein
MRKKLLMCFAMLFMCVCTALAQTKISGTVVSADDNEPVIGATIMVVGTKSGAVTDVDGKFSLTTDVANPQITVGYIGMASQTLKGTTDMKVVLKSSTQTLNEVVVTGLTRTDRRLFTGATDKVDAEKARLSGVADISRSLEGQAAGVSVQNVSGTFGTSPKIRIRGATSIYGSSKPLWVVDGVIMEDAANVGADDLASGNPETLISSAIAGLNADDIESFQILKDGSATSIYGARAMAGVIVVTTKKGKQGQAHISYTGEFTSRLVPSYSNFDILDSKEQMGIYRELADKGWLNFSDVLNGSEYGVYGKMYELINKYNANTGQFALENTTEARNRYLQRAEFRNTNWFKELFSSNIMQSHSISLSGGTQKSNYYASFSALLDPGWYKQSNVNRYTLNVNLTQHLSDKLSLNLIGGAAYRKQRAPGTLGQDVDVVGGEVKRDFDINPYSYASNTSRVLDPSATYVANYAPFNIFNELNNNYIDLNTLDARFQLELKYKPVKGLELSVLGAFKYMASTQEHFVKDNSNQALAYRAMSNGIIRDANKYLYKDPNNPYVLPMTVLPYGGLYHKGDNRMSDYDIRATANYSHTFAEKHIMNLFGGMELKSIERQRNVFEGAGLRYDAGMVPFYIYQYFKRALESGNTYYTINPTNSRSVAFYGNTTYSYQGRYVFNGTLRYEGSNQMGRNSSARWMPTWNVSGAWNVHEENWFNKLSPLNKLTLRASYSLTGTPPDASYSNSTAIITASTPFRLFAEDQEPQLELSELANSTLTYEKKNELNLGFDASLWNNRLGVTFDYYTRRNFDEIGPMVTAGLGGEIIRAANVAEMNSNGLELSISSVNIKKKNFSWTTSFIYSYATTEITKLFNQGNVMSLVSGNGFAKKGYPARALFSIPFMGLNSEGMPMVLNEKGQVTTDDINFQERTKTDFLKYEGPTDPTHTGSVGNMFSYHGFRLNVFFTYAFGNVVRLDPKFRARYNDLVSMTNAFKNRWMAAGEEAETNVPGILSKSQYMANTNVRLGYNAYNYSDARIAKGDFIRLKEISLGYDFPAQMFQNSMIKNASLKLQATNLFLLYADKRLNGQDPEFYNVGGVASPMPKQFTLTVKLGL

Crispr_ID: NZ_CP054010_6

• CRISPR_ID: NZ_CP054010_6
• CRISPR_location: 897347-897436
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_6

Consensus_repeat	Method
CATTTCACGCCCCTCCCTTTGGGGGAGGGGT	CRISPRCasFinder

spacers of NZ_CP054010_6

>6.1|897378|28|NZ_CP054010|CRISPRCasFinder
TGGGGGTGGGGCTGCTATCTCTCTCACA

CRISPR arrays and Neighbor proteins around NZ_CP054010_6

CRISPR arrays

The CRISPR arrays of NZ_CP054010_6

>merge|NZ_CP054010|6|897347-897436|CRISPRCasFinder
CATTTCACGCCCCTCCCTTTGGGGGAGGGGTTGGGGGTGGGGCTGCTATCTCTCTCACACATTTCACTCCCCTCCCTTTGGGGGAGGGGT

>NZ_CP054010|6|6|897347-897436|CRISPRCasFinder
CATTTCACGCCCCTCCCTTTGGGGGAGGGGT	TGGGGGTGGGGCTGCTATCTCTCTCACA
CATTTCACTCCCCTCCCTTTGGGGGAGGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	unknown	unknown	gnl|CDD|379719
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	unknown	unknown	gnl|CDD|269882
NZ_CP054010.1|WP_036885796.1|917541_918876_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|239488
NZ_CP054010.1|WP_036885797.1|913843_916186_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|379720
NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	unknown	unknown	gnl|CDD|271323
NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|369630
NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein	unknown	unknown	gnl|CDD|372921
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	unknown	unknown	gnl|CDD|226195
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	unknown	unknown	gnl|CDD|271342
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	unknown	unknown	gnl|CDD|372993
NZ_CP054010.1|WP_036885798.1|903849_904281_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	unknown	unknown	gnl|CDD|379166
NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein	unknown	unknown	gnl|CDD|275342
NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl|CDD|373012
NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	unknown	unknown	gnl|CDD|274948
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	unknown	unknown	gnl|CDD|153100

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein	gnl|CDD|379719	pfam14903, WG_beta_rep, WG containing repeat. This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).	7.18595e-10
NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein	gnl|CDD|269882	cd06596, GH31_CPE1046, Clostridium CPE1046-like. CPE1046 is an uncharacterized Clostridium perfringens protein with a glycosyl hydrolase family 31 (GH31) domain. The domain architecture of CPE1046 and its orthologs includes a C-terminal fibronectin type 3 (FN3) domain and a coagulation factor 5/8 type C domain in addition to the GH31 domain. Enzymes of the GH31 family possess a wide range of different hydrolytic activities including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase, 3-alpha-isomaltosyltransferase and alpha-1,4-glucan lyase. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.	0
NZ_CP054010.1|WP_036885797.1|913843_916186_-|TonB-dependent-receptor	gnl|CDD|379720	pfam14905, OMP_b-brl_3, Outer membrane protein beta-barrel family. This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.	5.62455e-58
NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein	gnl|CDD|271323	cd14953, NHL_like_1, Uncharacterized NHL-repeat domain in bacterial proteins. This bacterial family of NHL-repeat domains is found in a variety of domain architectures. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	9.68928e-20
NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	4.29635e-07
NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|369630	pfam07980, SusD_RagB, SusD family. This domain is found in bacterial cell surface proteins such SusD and SusD-like proteins, as as well RagB, outer membrane surface receptor antigen. Bacteroidetes, one of the two dominant bacterial phyla in the human gut, are Gram-negative saccharolytic microorganisms that utilize a diverse array of glycans. Hence, they express starch-utilization system (Sus) for glycan uptake. SusD has 551 amino acids, and is almost entirely alpha-helical, with 22 alpha-helices, eight of which form 4 tetra-trico peptide repeats (TPRs: helix-turn-helix motifs involved in protein-protein interactions). The four TPRs pack together to create a right-handed super-helix. This is predicted to mediate the formation of SusD and SusC porin complex at the cell surface. The interaction between SusC and TPR1/TPR2 region of SusD is predicted to be of functional importance since it allows SusD to be in position for oligosaccharide capture from other Sus lipoproteins and delivery of these glycans to the SusC porin. The non-TPR containing portion of SusD is where starch binding occurs. The binding site is a shallow surface cavity located on top of TPR1. SusD homologs such as SusD-like proteins have a critical role in carbohydrate acquisition. Both SusD and its homologs, contain about 15-20 residues at the N-terminus that might be a flexible linker region, anchoring the protein to the membrane and the glycan-binding domain. Other homologs to SusD have been examined in Porphyromonas gingivalis such as RagB, an immunodominant outer-membrane surface receptor antigen. Structural characterization of RagB shows substantial similarity with Bacteroides thetaiotaomicron SusD (i.e alpha-helices and TPR regions). Based on this structural similarity, functional studies suggest that, RagB binding of glycans occurs at pockets on the molecular surface that are distinct from those of SusD.	1.42649e-43
NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein	gnl|CDD|372921	pfam14135, DUF4302, Domain of unknown function (DUF4302). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 344 and 443 amino acids in length. There are two completely conserved residues (R and L) that may be functionally important.	1.5085e-57
NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase	gnl|CDD|226195	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism].	4.61922e-33
NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein	gnl|CDD|271342	cd14948, BACON, Bacteroidetes-Associated Carbohydrate-binding (putative) Often N-terminal (BACON) domain. The BACON domain is found in diverse domain architectures and accociated with a wide variety of domains, including carbohydrate-active enzymes and proteases. It was named for its suggested function of carbohydrate binding; the latter was inferred from domain architectures, sequence conservation, and phyletic distribution. However, recent experimental data suggest that its primary function in Bacteroides ovatus endo-xyloglucanase BoGH5A is to distance the catalytic module from the cell surface and confer additional mobility to the catalytic domain for attack of the polysaccharide. No evidence for a direct role in carbohydrate binding could be found in that case. The large majority of BACON domains are found in Bacteroidetes.	1.61174e-12
NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0
NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein	gnl|CDD|372993	pfam14274, DUF4361, Domain of unknown function (DUF4361).	6.672e-15
NZ_CP054010.1|WP_036885796.1|917541_918876_+|phosphatase-PAP2-family-protein	gnl|CDD|239488	cd03394, PAP2_like_5, PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.9511e-34
NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	6.0924e-58
NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein	gnl|CDD|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	2.76184e-33
NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein	gnl|CDD|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	3.3025e-179
NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl|CDD|373012	pfam14322, SusD-like_3, Starch-binding associating with outer membrane. SusD is a secreted polysaccharide-binding protein with an N-terminal lipid moiety that allows it to associate with the outer membrane. SusD probably mediates xyloglucan-binding prior to xyloglucan transport in the periplasm for degradation. This domain is found N-terminal to pfam07980.	2.11185e-24
NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein	gnl|CDD|275342	TIGR04549, LP_HExxH_w_tonB, substrate import-associated zinc metallohydrolase lipoprotein. Members of this family are lipoproteins with the typical zinc metallohydrolase HExxH motif and additional similarities to a better-documented zinc peptidase family, pfam06167. The seed alignment begins immediately after the lipoprotein motif Cys residue. Up to five members of this protein family occur per genome, in the context of certain gene pairs related to RagA and RagB, or to SusC and SusD. Those gene pairs, like the present family, are restricted to the Bacteriodetes, may number up to 100 pairs per genome, and are linked to TonB-dependent uptake of biopolymer-derived nutrients such as glycans. A possible function for this lipoprotein is to hydrolyse larger molecules to prepare substrates for import and utilization. [Unknown function, Enzymes of unknown specificity].	1.9574e-130

Protein sequences

>NZ_CP054010.1|WP_004359196.1|895090_896617_-|alpha-L-fucosidase
MNNRFLHGVLTALALTASATSFAQTNTVMTLKTQIAPNAENEPRPVFPVPTDRQWKWQQTEFYAFFHYGMNTYTNKEWGNGDEDVNTFAPTAKPDPRQWLEAVKEAGMTGGIAVVKHHDGFCLWPTETTDHKSSNSSSPNAQVNIAELFAKAAQDLKMKYGFYVSPWDRNSGLYGTDSYVKDVFLKQCAELAKYGSDQFEMWFDGANGGNGYYGGKNKTINIDRATYYDVPNLRDSIHKLSPNIILWGVGGEARWIGNEDGWAGETNWCNENRGFAPERNGMYGTENGWFWLPGESDAKFTDKGWFWHPGCEPMSAERTFQMYLETVGRNATLILNCPPDRSGRIPQNQVSRLKEFGTMLKSRFKTNLAKTATLEATNTRANGATRTYVVNNLIDENPDTYWAAEDDVKDVTLTFKWNSPQTVRYVTLQEYVRLGQRVKSFSIEYTTDGSTWKPLANKVKQTTIGYKRIIPLNGSTANSYGSGYDAKAIRIHIKDAKACPVMSEIAIY
>NZ_CP054010.1|WP_155812478.1|892762_895081_-|hypothetical-protein
MKNNMKKNILATCGLLFCTSLLHAQTTEEVRIDFENQNYKALGVYDTWLKSPFRSQNKQAAVLEGNVQVVSNIDKNYDEILKATPNASDNVLGFQRSRFGSNTFGARIDLKQPFALTKETKYVHVMIHKAKVGRTMLIGLGKRTDRAGQSVDTEQFWELSTREVEPNKWVDAVFPVKGAGGIEIHSLVVVVDCEDTNGLKDDFLAYIDNIVVNNEAFTTTNREDYPMNYNKDAKCSRTDRGLKGISLGDQTFNVYGDITTSIPAYTYLSKQAFLAKPGETLNPAVQYKGIWMHSYVYLDLNNNGRFEPKVEGGQIVPNAGNELLAYSFLGGEDENSGFNSAGTEISGNGRNTLVMPEFTLPSDLQHGFYRMRYKVDWNSADAGGSIENNNHILNNGGGAIDVRLNVHGDNVKIYQGALNGKVVAEDGTELNGISIPFGKPYTIKMKPEHGFNFSGLKVRHGYNLTGDSISHGTYQYVDELIPRERFNADGTFTLPAEMIDGDVSLEGIFIDAKTALTYEVYFNNEFVYSTVVNGAKTGAVTIPEGLSRDYVELIADKQTITSLPATVRINATWTAPMKVATPTDTTWYNLKVSNQPRWVSSGNYTPNVYFIDETYITTDYALWALTGNPYSGFRLINKAMGPTMVLASASPKGSAKAGGNTYATLLPADNLPAGYTSDWTVTISPNDDEGFYICNPEGFGLNYRADGNLAYWTGGKDAGSTFVPTEVKKTSTGINALIFKNESATTYDLSGKAVSKSHKGVVIRNGKKMLVK
>NZ_CP054010.1|WP_036885799.1|890401_891901_-|IPT/TIG-domain-containing-protein
MKRLFKSYLWMVLMGSLAWVSCSDKEVGGTAGTAFDPSQPIVISDFYPDSGGIATPMIITGKNFGTDTTGLALWYVDEDGRRHRGGLVSSNGEKLYCYVPAGLTYKRNIKLEVTRANGTDTIKGAGDRDFKYITQTAVTTIVGTQTSDAHATKIDKLLTSNLSAPGYLCVDNENNIFIVQHRFDDSFVANGSNSFIECRNEKNENVGGMVLKADLKRDQLSILQVNSNTKEKINAPAYSTLDGYEGVYVPDDSGRKYYSLLKDQGYAVHKQQFINPNGYANLDQSNWKYCFVINKNDQMIYSVMFKGQLIRINPKTRKAELLLKRVGKDGPKGDGGSDTFCTFSPTQPNRLFISFTDAHQIWYVDVDQLLDKDSLTYQGEPYAGISSFGTVNVTEGKGWEDGALKNAKFCYPRQMTFTKDGKLYIADSGNHCIRMIDTTLGKNARVTTPIGVPQSAGFQDGGVELAKFNWPTGVAVSADGSTVYVADSKNQVIRELSIK
>NZ_CP054010.1|WP_036885801.1|887255_890366_-|TonB-dependent-receptor
MRRTLYVLCLMVALLTYGLQAYSQDNSTAKQFSVAGVILDDTGEPCIGATVRVKNEPGVGTISDLDGKFNIKVKPGATLLFEYVGMETVQRTILKDEPSLSVKFKVAKTNAIDEVVVTGLVSQKKVSVVGAVSTINMDELRTPGTSLVNMIGGRMPGVITMQTSGEPGQNLSNFWVRGVSTFGAGAGALVLIDGIEGRLNDIDVDDVESISVLKDAAATAVYGVRGANGVVLVTTKRGSKEKIQVTARATVKLSQIKRLPEYLSSYDYARLANEARAMSGESDLYTPIQLDIIKNNLDPELYPNVNWIDQIMKKTSLQENYYASARGGGDVAQYFVSVGYRHEGAAYKQKENQFHRPLSYDQLTYRANINMNLTKRSELYFGVDGNISNYTTPGGKNTNQVWSDVLQLNPLMFPVTYADGTLPTYGQSDLISPFAALNYQGYKSSDYSRNMITLKFTHRFGGILKGLVGSVQAVNDRTAGFSERRFVRPDYYRATGRTSTGDLIKTLRSKQQDMSYSSDNESWRKYYMEAKLDYNTSFGAHNLGALLFYYMEDTKGSEWGNGDALGIAAIPKRRQNVSGRLSWGYNSTYFVDANFGYTGSDLFPKGQRFGFFPSIAVGWAPTSYKWVQKHLPFVNFFKIRGSYGLAGNDNIANTRFPYLTIINNHAGTTWGYNGSGIVEKQQGADNLKWEVAKKLNVGIDANFFNDAIKLNVDFFRDTRDHIFQDRVTLPEFAGMVTYPKSNVGRMHSFGSDGNISYFHKINKEMNFTVRANYTWSQNIVDYFEENKLAYDYQSVTGMPYGVLRGYIAEGLFKDEADIRQSADQTAAFGVVRPGDIKYRDVNGDGVINKDDRVPLSYGNNVPRVMFGIGGEFNYKDFTVSMLFKGNTGVNYYRVGMGYDAGWIPFYNGEMGNVLKMVNNPKNRWIPSWYSGDPSTENPNAMFPRLSYGSNANNSQLSTFWKKNGSFLRFQELNFRYVFRHRKWLRAAGLSALECDFVINNLFTIDSAKYFDPEQAWFNGAAYPIPTTYSLQMYFRF
>NZ_CP054010.1|WP_004359200.1|885195_887226_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKKHILALGAVAALFSGMTFTSCNFLDQDDNFNAIFKEDSVFHSAQNANGYLFATPTMFPSAGNIWGNSWTPGETASDEICVRWQTNEFWGAKFTVGNVNAENVPNWGYWYQMYKIINRCNRMLANVDKIGDMSNNDKADYKAMVHFIRGYAYYVLLQNWGPCLIVNDEVISTSEKADYYDRERATMDESIDYICNEFAQSLPGLKRPSEQSTAYFGRPTKGTALALIARLRLLQASPTFNGGTYAKRCFGEWKRKSDGKYYVNQDYDAKRWAVAAAAAKQVIDLNYYTLFTVDADKDNPYPLDASVPTAKFPDGAGGIDPYHSFADMFNGEGTAKVNREFIWADEYSGPVMNYSRHSFPVNYGGWGGMSVPQRVIDCFLMKDGKKPAESPLYEADLTKHVNQKKSIGDCDMANGTPLAYTNRSARFYASIGFPGRIWKMNSTTDGSYNNQTFWYSIDDSKAGKNAAGNNPNDYCISGYVPFKYIHPDDSWHGKDGASVIPKPFPIIRYAEILLIYCEAANHIQGSETVKTWDVSGRLVDVAVTRDEAAMARYFNMIRYRVGLPGVEAATLSSENAFDEVIKNERQVELFNEGYRYFDTRRWGTYFTEDANSSNWRGLDVYSEKKGNNDGPFFNLVTINEQNIRDRKALPRMVFLPLMHRELLKSPKMDQNPGWDR
>NZ_CP054010.1|WP_004359201.1|884113_885172_-|DUF4361-domain-containing-protein
MKKYKYILGCALAAVALSSCNNYDFEQNFYPHKVGLMAGTNRIYDRTTVELSTVENGTASVQLVANLSGSQLADRDYHVTIAHDDSLFNAYNKSNFDIDSTKFARLLPQNCYEDPAMAGTIPSGSNKCLFDIKLKNLGTLSPDSTYFLNYKIVSHDASALATDNNKLGVKLDHVLIKVTWKNAYGSTAEGWNYQLVSSQVTNLETKSTTRPTNTVRAFPVAANAVRFLAGDEKWDNYEKALHDINVKSIVATIGSKTVTNPSAYNVTLKPYKQDSLEVEMLTPVGEYNNTFLLNELGGSASTNPTYFKEFRLHYRYRVMKNAKQNDGTWKAGPWKEVLSKLRYQYNPRADKL
>NZ_CP054010.1|WP_004359202.1|882287_884093_-|BACON-domain-containing-protein
MKLKINFLFILSVLFVGTLGLASCATDYDTDFTGKELEVPHSSQRMIAFNKEGGEQQIAVETNVALDEWKAESNADWLTVTKNADGKGVTVKTPAYDGFKAREAKVTISHGERASYEIKVSQMGFESVLRIPEQNPFFNREGTFYSLLESKVTSIDVPVETNLNLDHIIVPDTVSFVRLDASKTVKENGIVKLHFDMDPNTTSEKRYCTVRLKSSDNWDASIEYVIEQAAKGYKVRPIYPVETKQASVEMIDLGRTYRVPFQRTAVDGNYEVIIPDNAKDWLSTTKKFIAGSEVVFTTTLNTTDSPRSCDVVCKPSNGSTQPFTIHVTQQAFQDIVPTGVSELNVTPGKGQFNVSWKAPDEVNYEKVIVRAKSNMPGVPESVKEVAATETSCVLNDVFNFAGNYTITVTTQGLRGKNTDAPATATAQANEWSESVEIPLTAAMVSSNSMQPGHEIGSAVDGNKTTYFQTKSNGSTSDPRPHIDITLNEGINGTFYLAFDENKVTSNDRNPKKANIYASSDVITATTRPLTQTNFRSANAVSEPLSYTKTNGVTVTHIRFEPTQRKNGTNINNGGGSSYWYLAELHLYVYHDEAWKREQLGL
>NZ_CP054010.1|WP_004359203.1|878881_882073_-|hypothetical-protein
MLFERFLRKKTLMAALALTAAVPSVAKASMLSAAPTADGENQKLKPGVYYIVNDKRQKGTDLHVFVNDEGTLHGQHYGSPSTDFSDLFLLRAKDGRYTIQSLKNAKYVQSVGQNNEVYKTANDAYKFRIIYQTESSGTGKSYFNIYNSNAEDWCWHIDAQKNIVRWKPLMDNGIRAVGPSEFRFDPVTTLTNEQVLARLAQLTKVVDPTKDLTKYYQIVSDTYGRSMREDFIVGELSTSGFNSSDYSYYWKLERLANGRYVFQNAVTGKYIVPQNGQTSRSYTTAEGKGTGFDLQRNTDDPYGLAFEMVDANNVGIHCAESQGYHPVGWYTHNEANKWVFKEATLDPAKLKEQQEAYKARVDLTKNVDVYAEKVAKYFTNSAATEVTAATKAMTDEALKAQMTTEGVPQGLQEVVLKIKNQSWTAYPSGRNWEKLFRIADYKVYSENNYNAWARSMGIGYDYGSMTNPTGITARDGEDLFVFLGDDIPQNATVQIELVPLGTRSAGKYYSLKKGLNIILNQGENNVFVNYIGRTFNNGKYLRDYKPMNIHIEGGKVNGYFDLTKGNTNEDWQKMQSDGLVWAKAFNMKGELVVMNMPGADCKRYTPVHMKELVEIWNSIVQREDDLMGFRAAKRDKCNNVLNATAVDHGYMYATTGGTYYNYNTLGDVLNYDKMKWGNGTLWGPAHEFGHNHQQLFNTAGMTEISVNMYSNMVMFTSGRVTSRSENCSYTDVDGKKYDGVCESAVSTYADRFANKKKWFEYGTWGTTQMYYKLYMMFHSTGLDNQFWHKCLDYLRTHRLEGQGTANCQGQNDYLLFAKACSYAAQQDLSSFFEAWGHFYDVNGSVIGDYSNTTMYTTRAQWMEAKKFMQKYPKGPANNMIFIDDHIRRTPATYPGHAAGEMREDFNGAVRVGRMGDFGSWDQFCPDSLGQGYAIIKTQSDANGKRTYTMEAKNSHVVGFKIYNSKGQLIYFANTKTFTIPKKVMEDAKNDIKVKVCGSDGSEVDPGTVPLGITTFSAQANGGKVDVYSIYGVLVRSKVNAETALEGLPNGVYVVGGKKVVVGK
>NZ_CP054010.1|WP_050759731.1|877347_877998_-|WG-repeat-containing-protein
MKRLQLIVPMLACCLALPCLSFTDVKDSYLVLQVDTTQKYEQYSYVNEKGETVVPSNRYLLCYTDTIRTIGFVLKPNVGCVAINTQGQELFNVYMVDNGNDYPVNGLFRILDESGQKMGVANMEGKVIVNPKYDAIFPYHDGLAAVAVGSKTVRPADDPEHEYTVGGKWGFIDKQGNEVIPLEYDSIANYRRFVNGKALVLKHGKWIKLSIRQKKR
>NZ_CP054010.1|WP_004359205.1|876289_877135_+|hypothetical-protein
MFVLFFLCFSIYGKAQTAPKKLTAPSPERFQAINDSILAEGMWLYTYEKLAWRATDSLMKYNVKREEINSATAFEEGNLTWRYIFANLDKEQTVFELTLHLSNDTSFYVCSATPRKLKPTEIEQLKAKQIAPRKVIKEKGDSIFLSNTSGLNWDLIPLTNGCYRLYLLHGTTKHGVIPIGDDYAFDFDKDMNILSWRRFHRSFLEQPITMNGEKITEVMHSHTPMTPYFTTTDIANYMLYGCDLYGIKRFSVLSTAFADTSYLTTFDVEKMKLTSTVYTVK
>NZ_CP054010.1|WP_004359195.1|897477_901275_-|DUF5110-domain-containing-protein
MKKKKAKILLAALLLAVGETAFADGKAVSGIRQINPTTVEITYSDGGVMTVDFYGQNVFRLFRDPKGGIVRDPVSNPPARILLDNPRKNAGRLSVNETDADVAVATAEVRVRFDRNTGLMTVTDLRNGKEVIKEVKGVDFQKNRTTVTLANAAGEYFYGGGVQNGRFSHRGKRIEIVNTNSWTDGGVASPAPFYWSTGGYAAMPYTFAPGAYDFGSTDKNTVTISHEMPYLDLFLMVDTTPVSLLQDYYQLTGNPVLLPKFAFYEGHLNAYNRDYWKETTEEGKGILFEDGKRYVESQKDNGGIKESLNGEKQNYQFSARAVIDRYKKDDMPLGWILPNDGYGAGYGQTSTLDGNIANLKSLGDYARKQGVEIGLWTQSNLHPVDSIPALLQRDIVKEVRDAGVRVLKTDVAWVGAGYSFGLNGIADVANIMPYYGSDARPFIITLDGWAGTQRYGGVWSGDQTGGEWEYIRFHIPTYIGSGLSGMGNITSDMDGIFGGKNLSVNIRDFQWKTFTPMQLNMDGWGSNPKYPQALGEPATSINRSYLKLKSMLLPYTYSCAHEAVTGKPLMRAMFLDDSNDYTHSSATRYQYMYGPSFLVAPIYQNTAADKEGNDVRNGIYLPKGTWYDYFTGATYEGGCVLNDYFAPIWKLPVLVKSGAIIPMVNANNNPSEIDKNRRVFELYPDGKTEFTLYDDDGTTQKYLSNEKATTRITSDLNDKQVLTVSIDKTEGTFDGMVKNQSTTFYLNTNAKPKKLTAVIGGKKIRLTEAEQGDNTWQYVQASNINRFSTTNSEMERLLVTKNAQIIVRLASCDITKEAVELRVEGFARLNKSNETLRKKGALTAPELLEADVQSYSVTPKWKPVQNADYYEIAFNGQTYTTIRHNSLLFDDLQPATDYDFKVRAVNSEGASEWMPLHVKTAVNPLEYAIQGLTATSTARDMEGFEIHRLVDFSTTGDIWHTYYYTKAVPFDFTVDLHSTNTLDKLQYVPRANGGNGTITKCDIAVSKDGRNWTEIGPQQWARDGRTKEVTLSTHPVARYVKVSVKEAVGNFGSGREFYVFKVPGTKTILPGDINLDGKVDENDFTSYMNYTGLKKGDADFDGYISGGDINGNGLIDAYDISNVAMHLEDGWNDDDVAPVGGKVYYEYNRKSYAAGDDVIIKVKGKDLQSVNAFNLIFPYSPKELQFVKVETDPSMVMRNLTYDRHHSDGSQVLYPTFVNVGDHHTFNGDADLLVIRMKALKPFTVKPQTAKGLLVDKQLEEVELK
>NZ_CP054010.1|WP_004359194.1|901999_902653_+|rubrerythrin
MKKKFICTVCGYIHEGTEAPAECPVCHAKAAKFKEFNPEALKGTKTEQNLKNAFAGESQAHTKYLYYASKAKKDGYEQIAGFFEETARNEKEHAKIWFKFLHEGDIPTTTVNLADAAAGENYEWTDMYEQMAKDAMEEGFPELAVKFRSVGKVEKHHEERYRKLLKNIEDSVVFSREGDCIWQCRNCGHIVIGKKAPAVCPVCNHPQSFFQVEESNY
>NZ_CP054010.1|WP_036885798.1|903849_904281_+|hypothetical-protein
MNTLKISIITCFSILYSLTSFAEVKSNVSIEIGSFDSIPSEIDGGCCVFYKYPNKMRNKSYIMVNDLATTAYMVINRRLEEFTLVSNWKDVFWYKNKRFTLKVTINHTQSKGDNEFYKVKGILIVEDRNKNQQKLSFCGNCSW
>NZ_CP054010.1|WP_004359192.1|905074_906139_-|BACON-domain-containing-protein
MKKYISIFLLVAAAVLGTACSNDNNELPEYAAGLNVVKAQTAFNVIGGTNMVKMASEPAQAYAQDAWLTVTKKAETLELTATTNTSPQSRNTLLVIKNLQGDSITLNVQQEGVTFGLPAGEDIFTDDKAIQKTLIATANVPVTYVTTGDWITVEQKGNEVGVKVAENTTGKARVGWVIAKAVGLVDSLKVVQASLSDFVGEYKQTAKMRNADRTLSKKISDVRIEAMGTNKANFIVDNKYTWAVDFIPGKGFKMTNGKVVAKNEVQTGVYEYFISVIVADDFSKEHETAINGTQESILLAIDDAGNLVFKEAQKLASEQTFSSYGWNRFSDTKPVMGAYRGIGEVYVQPKLTRK
>NZ_CP054010.1|WP_036885880.1|906141_907419_-|DUF4302-domain-containing-protein
MKKVYLLFMAIVLTLSLQSCLHDDKTTFDLPAAERIEKKVADYKALLESSEDGWVMQYYTGKNYSYGGYTLLLKFKNGHVTAMGDVKDVEAKATSGYGVVKDLGPTLSFNEYNAVIHPLAETWLGSPDGAQGDYEFSILRATNDSIFVRGRKWHNDMVLTRLPKGTNWEEYMLGLVTVMEGMNVETYDFVLGNDTLGQGTLTQEVRRLTVTLGDKKWEMPYCTTNTGIVLREPIVIGNKKYQRFTWNDGDHSLTQDDLKIIQFLPKSHKSIDFWVGEWQLKTNLRKRIRLTLEKGSVANTLKGKLNINNINYEILLTYDPATGHLEFPGQPVTDPTYKYPAGIVMIPASQKEGKLFGEGKGSLFFTWDEDMQRAKAEDSGQITGHAVDSFFGVAYGEDLQPVTDAQGNYVFAFTLPNIQYMTKIN
>NZ_CP054010.1|WP_004359190.1|907555_908443_-|hypothetical-protein
MKKYLYLVTIALVSCCAVLSSCSDDKISGDSIFSTKAVERNAFDQWLYKNYTMPYNIDFQYRLKTEETEQAYNFVPADSAKTVKLAILTKYMWFDAYAETVGLDFIKENAPRIILVTGTPGYTRYRTEVIGSAEGGYKVRLGKVNALTDEQLKDYGSMNNYYFHTMHHEFMHILNQKKPYDESYDNISRSDYVSGNWTSIPDKKAQSMGFVSAYSMENPAEDIAELYSIYVTSTPEDWATIMKNAGNKGGTIINKKLKIIREYMSNSWNVDIELLRNAILRRGGKIGTLDLNTLE
>NZ_CP054010.1|WP_004359189.1|908454_910038_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKVKKYIIYLPVAAISLALTSCNDFLNKYPDSRMDLKNPTEVSQLLVSAYPQAHPAYLTEMYSDNTDEQLHSTWSAFDRFQEQAYQWKDIDDVSNTETPYQLWSAHYAAISACNEAIEYIEHTVKDAQSEEDYRAQLGEALLCRAFSMFQLSTVFCQAYDKTTAANQLGLPYPTEPEKVVGRLIERGTLAELYQKIEADMLKGIALVGTKYAKPKFHFTKQATYAFATRFYLYAQKYDKAVKYANMVLGDQPADILRNWAEWNRLGPSGNVQPNAFVNASNNANIMLLPVPSQWGVISIPIQAGSKYAHGELISKNETLQAPGPWGDSGSTLNYTVLYNNGVSKYCLRKIPYVPKVIDATAEIGVPYGEYAVFSTDITLLERAEAYALLGQYDKALKDINTELTVFSKNRKQLTLADIQDFYGSMAYYTPTKPTPKKKLNPLFTVEATTQEPLLQCLLQLKRLVTIHEGFRLQDVKRYGITMYRRKVDVQSNVTAVTDSMKVGDPRLAIQLPQDVITAGVKPNPRNN
>NZ_CP054010.1|WP_004359188.1|910049_913364_-|SusC/RagA-family-TonB-linked-outer-membrane-protein
MRKKLLMCFAMLFMCVCTALAQTKISGTVVSADDNEPVIGATIMVVGTKSGAVTDVDGKFSLTTDVANPQITVGYIGMASQTLKGTTDMKVVLKSSTQTLNEVVVTGLTRTDRRLFTGATDKVDAEKARLSGVADISRSLEGQAAGVSVQNVSGTFGTSPKIRIRGATSIYGSSKPLWVVDGVIMEDAANVGADDLASGNPETLISSAIAGLNADDIESFQILKDGSATSIYGARAMAGVIVVTTKKGKQGQAHISYTGEFTSRLVPSYSNFDILDSKEQMGIYRELADKGWLNFSDVLNGSEYGVYGKMYELINKYNANTGQFALENTTEARNRYLQRAEFRNTNWFKELFSSNIMQSHSISLSGGTQKSNYYASFSALLDPGWYKQSNVNRYTLNVNLTQHLSDKLSLNLIGGAAYRKQRAPGTLGQDVDVVGGEVKRDFDINPYSYASNTSRVLDPSATYVANYAPFNIFNELNNNYIDLNTLDARFQLELKYKPVKGLELSVLGAFKYMASTQEHFVKDNSNQALAYRAMSNGIIRDANKYLYKDPNNPYVLPMTVLPYGGLYHKGDNRMSDYDIRATANYSHTFAEKHIMNLFGGMELKSIERQRNVFEGAGLRYDAGMVPFYIYQYFKRALESGNTYYTINPTNSRSVAFYGNTTYSYQGRYVFNGTLRYEGSNQMGRNSSARWMPTWNVSGAWNVHEENWFNKLSPLNKLTLRASYSLTGTPPDASYSNSTAIITASTPFRLFAEDQEPQLELSELANSTLTYEKKNELNLGFDASLWNNRLGVTFDYYTRRNFDEIGPMVTAGLGGEIIRAANVAEMNSNGLELSISSVNIKKKNFSWTTSFIYSYATTEITKLFNQGNVMSLVSGNGFAKKGYPARALFSIPFMGLNSEGMPMVLNEKGQVTTDDINFQERTKTDFLKYEGPTDPTHTGSVGNMFSYHGFRLNVFFTYAFGNVVRLDPKFRARYNDLVSMTNAFKNRWMAAGEEAETNVPGILSKSQYMANTNVRLGYNAYNYSDARIAKGDFIRLKEISLGYDFPAQMFQNSMIKNASLKLQATNLFLLYADKRLNGQDPEFYNVGGVASPMPKQFTLTVKLGL
>NZ_CP054010.1|WP_036885797.1|913843_916186_-|TonB-dependent-receptor
MIMVKSLHSILQFTPISFIFLLLSSQPMYAQQWQLKGRLVEKVDRTTPLDAAEILVSPLGGDVTSSSLSDEEGRFALSLSSGKYVFRYRQLGDILKTDTLDVQADTDLGDIPLEIKKYTMKEVTVTSQRRMLSQKAGKLVYLVQNSPFAQGFSTRDLLHNIPRIDPTSEEIKIIGKSNVLVLVDGHRVNLEGKDLDMYLRTLPSENISKIELITNPSARFDAAGNSGVLNIILKSKPVGFDGKIHTLLTQRTHFAAEEGADLSFSSGNFSVEYKVDNSNEKRPQKMKSSYIYPTYTRVTNDYTLNRYDILSQNLNSSYQIGHVKIGFFSTLNRSRNKGFHKGEMNFSDGSYPSNTYSEQTHDKYRLETISPYVEWKLDSIGKKLTLNYNYIHLSDDVNQVYDSGSAHPFSSSWDNYSNVVNTLSADLNLPFTWLNFEVGGKYSHFRTNNISDYGGSNGFLFKETITALYADVHRNFGPFYAKAGLRYEHTSNNGITLGGLTVSNKYHHWFPFAEFSYNPSDDHSFSLGYSKRINRPSMNNMDPTKVYRDTYSYSEGNDRLVPSIMDNLEFNYVFKGNLNVDLYYYHTSDAIQSLIQVVDDLYTKYYPKNCLTINTYGGDVSYNFSWGKFNLYTSASMYYLKAKSMAEELDDSDLKSLNTTLSANLSYRYKAMTIFANYYHVFPGVEESFHTGNIDCLGLGCKINLLKNKLLLNVLAQDIFGGTKAHNRVAYNDYMFRNNIDNDNTSLRVGLTYNFGKHKAKRTDVNINNSEMNRLPDIKK
>NZ_CP054010.1|WP_036885796.1|917541_918876_+|phosphatase-PAP2-family-protein
MLIEEMKRFKELFFIPILFVCLCCQAKASAVLQDSIQLADSIKTVDSLSLVADTGLVPSIKCVPAEGEDKSCNTCKPHFDRIIYTCAPLIINGLIMKGQSRQFRGLRNDYIPRFDRSLDNYTQYLPAAVMLGLKVSGMKGRSSWGRMLASDAMSVALMAGIVNSLKYSAQVERPDGTDLRSFPSGHTATAFMTATMLNKEYGYRSPWIGVGAYTVAAATGLMRMANNKHWLSDVLTGAGIGIVATELGYYFTDLIFKNHGLRKADVEEKFDKLQKPSYVGLDFLINEPLGTYLNEKGSKVKVSRGCTSAVEGAYFFNPYIGVGGRFSVTRTSVIVDNVKAEDNVFDTWKLGGGAYFSYPLSERWLLGSKLLVVSVFYPDIKLTDDLIDSHHGVGFGTGLSLTFRVRQHYNVRFLMDYNLLPYRVSGVRTCFHSLGLGSSFVISF

Crispr_ID: NZ_CP054010_7

• CRISPR_ID: NZ_CP054010_7
• CRISPR_location: 957445-957526
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_7

Consensus_repeat	Method
CGACTACGAATTTCTCTAATTAC	CRISPRCasFinder

spacers of NZ_CP054010_7

>7.1|957468|36|NZ_CP054010|CRISPRCasFinder
ACTAATGCTTTTATCCCTTGAATTTTGAACTTTCAA

CRISPR arrays and Neighbor proteins around NZ_CP054010_7

CRISPR arrays

The CRISPR arrays of NZ_CP054010_7

>merge|NZ_CP054010|7|957445-957526|CRISPRCasFinder
CGACTACGAATTTCTCTAATTACACTAATGCTTTTATCCCTTGAATTTTGAACTTTCAACGACTACGAATTTCGCTAATTAC

>NZ_CP054010|7|7|957445-957526|CRISPRCasFinder
CGACTACGAATTTCTCTAATTAC	ACTAATGCTTTTATCCCTTGAATTTTGAACTTTCAA
CGACTACGAATTTCGCTAATTAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_155812477.1|960753_961314_+|restriction-endonuclease-subunit-S	unknown	unknown	gnl|CDD|341149
NZ_CP054010.1|WP_036885792.1|947335_950245_-|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|379720
NZ_CP054010.1|WP_036885793.1|940719_943095_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP054010.1|WP_004359159.1|959724_960210_-|peptidase-M15	unknown	unknown	gnl|CDD|311960
NZ_CP054010.1|WP_172891300.1|963103_964492_-|restriction-endonuclease-subunit-S	unknown	unknown	gnl|CDD|341163
NZ_CP054010.1|WP_036885791.1|961720_962524_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271191
NZ_CP054010.1|WP_004359150.1|966091_968800_-|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|226581
NZ_CP054010.1|WP_004359151.1|964668_966090_-|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl|CDD|223363
NZ_CP054010.1|WP_172891299.1|962500_963109_+|restriction-endonuclease-subunit-S	unknown	unknown	gnl|CDD|341182
NZ_CP054010.1|WP_004359164.1|952841_955343_+|YfhO-family-protein	unknown	unknown	gnl|CDD|370572
NZ_CP054010.1|WP_152031158.1|958250_958343_-|smalltalk-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359163.1|955730_957056_+|Na+/H+-antiporter-NhaA	unknown	unknown	gnl|CDD|377746
NZ_CP054010.1|WP_004359170.1|943113_944295_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359173.1|937074_938772_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP054010.1|WP_004359169.1|944423_945404_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225117
NZ_CP054010.1|WP_004359161.1|958585_959107_-|HU-family-DNA-binding-protein	unknown	unknown	gnl|CDD|375718
NZ_CP054010.1|WP_004359166.1|951229_951724_-|S-ribosylhomocysteine-lyase	unknown	unknown	gnl|CDD|376888
NZ_CP054010.1|WP_050759730.1|951982_952735_-|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase	unknown	unknown	gnl|CDD|350159
NZ_CP054010.1|WP_004359172.1|938774_940520_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP054010.1|WP_004359147.1|969343_970453_-|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl|CDD|225635

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_155812477.1|960753_961314_+|restriction-endonuclease-subunit-S	gnl|CDD|341149	cd17260, RMtype1_S_EcoEI-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to S.EcoEI TRD1-CR1, S.EcoJA17PI TRD1-CR1, S.EcoJA23PI TRD1-CR1, and S.StyLTIII TRD1-CR1. Escherichia coli A58 S subunit (S.EcoEI) recognizes 5'... GAGNNNNNNNATGC ... 3', Escherichia coli UCD_JA17_pb S subunit (S.EcoJA17PI) and Escherichia coli UCD_JA23_pb S subunit (S.EcoJA23PI) recognize 5'... GAGNNNNNNNGTCA ... 3', and Salmonella typhimurium LT7 S subunit (S.StyLTIII) recognizes 5'... GAGNNNNNNRTAYG ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example: S.EcoEI TRD1 and S.StyLTIII TRD1 recognize GAG/CTC, S.EcoEI TRD2 recognizes GCAT/ATGC, and S.StyLTIII TRD2 recognizes CRTAY/RTAYG. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It also includes TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases, such as Pseudomonas putida Jo 4-731 Type IIG restriction enzyme/N6-adenine DNA methyltransferas RM.PpiI and Porphyromonas macacae COT-192 OH2631 RM.Pma2631ORF8845P, as well as type I DNA methyltransferases such as Chlorobium limicola M.Cli245ORF128P. RM.PpiI recognizes the sequence 5' ... GAACNNNNNCTC ... 3'.	3.06504e-56
NZ_CP054010.1|WP_036885792.1|947335_950245_-|outer-membrane-beta-barrel-protein	gnl|CDD|379720	pfam14905, OMP_b-brl_3, Outer membrane protein beta-barrel family. This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.	3.22812e-06
NZ_CP054010.1|WP_036885793.1|940719_943095_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	8.44065e-47
NZ_CP054010.1|WP_004359159.1|959724_960210_-|peptidase-M15	gnl|CDD|311960	pfam08291, Peptidase_M15_3, Peptidase M15.	1.13966e-17
NZ_CP054010.1|WP_172891300.1|963103_964492_-|restriction-endonuclease-subunit-S	gnl|CDD|341163	cd17274, RMtype1_S_Eco540ANI-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to S.Eco540ANI TRD1-CR1, S.Eco2747AII TRD1-CR1, S.Eco540AI TRD1-CR1, S.Eco2747II TRD1-CR1, and S.Eco540I TRD1-CR1. Escherichia coli ST540AN S subunit (S.Eco540ANI ), Escherichia coli ST540A S subunit (S.Eco540AI), and Escherichia coli ST540 S subunit (S.Eco540I) recognize 5'... GAANNNNNNRTCG ... 3'. Escherichia coli ST2747A S subunit (S.Eco2747AII) and Escherichia coli ST2747 S subunit (S.Eco2747II) recognize 5'... GAANNNNNNNTAAA ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	1.15933e-67
NZ_CP054010.1|WP_036885791.1|961720_962524_-|tyrosine-type-recombinase/integrase	gnl|CDD|271191	cd01191, INT_C_like_2, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.9201e-110
NZ_CP054010.1|WP_004359150.1|966091_968800_-|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	5.75991e-98
NZ_CP054010.1|WP_004359151.1|964668_966090_-|SAM-dependent-DNA-methyltransferase	gnl|CDD|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	1.85786e-72
NZ_CP054010.1|WP_172891299.1|962500_963109_+|restriction-endonuclease-subunit-S	gnl|CDD|341182	cd17293, RMtype1_S_Ppo21ORF8840P_TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Paenibacillus polymyxa SQR-21 SQR21 S subunit (S.Ppo21ORF8840P) TRD1-CR1, Nitrosococcus halophilus Nc4 S subunit (S.NhaNc4ORF3964P) TRD1-CR1. The recognition sequences of Paenibacillus polymyxa SQR-21 SQR21 S subunit (S.Ppo21ORF8840P) and Nitrosococcus halophilus Nc4 S subunit (S.NhaNc4ORF3964P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This superfamily contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	4.52321e-74
NZ_CP054010.1|WP_004359164.1|952841_955343_+|YfhO-family-protein	gnl|CDD|370572	pfam09586, YfhO, Bacterial membrane protein YfhO. This protein is a conserved membrane protein. The yfhO gene is transcribed in Difco sporulation medium and the transcription is affected by the YvrGHb two-component system. Some members of this family have been annotated as glycosyl transferases of the PMT family.	1.9779e-08
NZ_CP054010.1|WP_004359163.1|955730_957056_+|Na+/H+-antiporter-NhaA	gnl|CDD|377746	pfam06965, Na_H_antiport_1, Na+/H+ antiporter 1. This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyze the exchange of H+ for Na+ in a manner that is highly dependent on the pH.	6.75895e-175
NZ_CP054010.1|WP_004359173.1|937074_938772_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.42011e-139
NZ_CP054010.1|WP_004359169.1|944423_945404_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.87215e-22
NZ_CP054010.1|WP_004359161.1|958585_959107_-|HU-family-DNA-binding-protein	gnl|CDD|375718	pfam18291, HU-HIG, HU domain fused to wHTH, Ig, or Glycine-rich motif. Rapidly-diverging family of HU domains predominantly observed in the bacteroidetes lineage with a predicted role in recognition and possible interception of the DNA of parasitic elements, a counter-conflict strategy preventing incorporation of these elements into the host genome.	3.90955e-27
NZ_CP054010.1|WP_004359166.1|951229_951724_-|S-ribosylhomocysteine-lyase	gnl|CDD|376888	pfam02664, LuxS, S-Ribosylhomocysteinase (LuxS). This family consists of the LuxS protein involved in autoinducer AI2 synthesis and its hypothetical relatives. S-ribosylhomocysteinase (LuxS) catalyzes the cleavage of the thioether bond in S-ribosylhomocysteine (SRH) to produce homocysteine and 4,5-dihydroxy-2,3-pentanedione (DPD), the precursor of type II bacterial quorum sensing molecule.	1.44347e-88
NZ_CP054010.1|WP_050759730.1|951982_952735_-|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase	gnl|CDD|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.10878e-82
NZ_CP054010.1|WP_004359172.1|938774_940520_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.85396e-133
NZ_CP054010.1|WP_004359147.1|969343_970453_-|HigA-family-addiction-module-antidote-protein	gnl|CDD|225635	COG3093, VapI, Plasmid maintenance system antidote protein [General function prediction only].	5.20231e-17

Protein sequences

>NZ_CP054010.1|WP_004359163.1|955730_957056_+|Na+/H+-antiporter-NhaA
MRQRVEKKLNQHLMLPIKLFMGREKSGGIVLILSVTLAMILANSNIAESYFHFFEQEVGFIVNGEPYLNYSLHHWINDGLMAMFFFVVGLELKREFIGGELADIRNTILPIGAAIGGMIVPALIFLSLNIGTPQTMGWGIPMATDIAFALGVVYLLGDKVPVSAKVFLTTLAIVDDLGAVLVIAFFYTSELSIASLLFGLGFLAVMFIGNRLGIKSLFFYAALGIGGVWVTFLLSGIHATIAAVLAAFMIPADAKINESVYLKRMKKLTRRFEHEEANEVRTLEEGQVDVLTHIQHDTEIAIPLLQQLEHKMSPIVTFLIMPIFAIANAGISFTDLSLSDIFSTHVALGVTLGLLLGKPIGIIGATFLMVKMRWATLPSAITRRTLLGLGMLASIGFTMSMFISTLAFTDELLMTQAKLGIFLASILGGIGGYVLLNKKSK
>NZ_CP054010.1|WP_004359164.1|952841_955343_+|YfhO-family-protein
MKTWKRFLPDVLVVVLFAVISFAYFFVPVTQGKILYRHDASAGVGSAQEMTEYQNRTGEATRWTNAIFGGMPTYQMSPSYQSTDGLSQVMNAYHLWLPDNVWFLFVYLLGFYILLRAFDFRQSLAALGSIMWAFSSYFLIIIAAGHLWKVMALAYLPPMIAGIVLAYRGRYLSGFIVTAIFTAFEVKANHVQMTYYYLFIVLFMVIGYLVQAVRQKQLVGFLKASGVLAVAALIGILINLSSLYHTWEYQKESMRGKSELLKADGANQTSSGLDRDYITQWSYGIDETMTLLVPDAKGGASVPLSQSSTAMSKVDPQIQSMIPQLYDAFPQYFGTQPGTSGPVYVGAFVLFLFILGLFLVKGTMKWALLAATILSVLLSWGHNFMGFTNFFLDYIPMYAKFRTVASILVIAEFTIPLLAALTLKRLVDEPELLGQKMKYAYISLGLTAGVALLVALFPDMMGPFVSDQERQMINSIQGMDGNTAGTILANVSAMRAAMVSSDAWRSVIVILIGFALLFAYKMKKLRADYMVAGLLVLCLVDMWQVDKRYLNDEMFVPKSERDMPQQPTAADLEINKDKSLDYRVLNFASNTFNENETSYFHKSIGGYHPAKLRRYQEMIDAYIAPEMQKTMQAIAAAGGNMQAVDGVKIFPVLNMLNTKYFILPLQGGTTAPIQNPYAQGNGWFVNKLTYVDDANAEYAEVGKIDVRHEAVADKKFEATLGQAKVNDSTATVKLDKYEPNNLQYTVNSKNGGVVVFSEIYYPGWTATIDGQPAELGRVNYILRAVSVKPGKHTVVLDFHPTSISTTETIAYIAIVILLLAIAGAGYMEWRKKK
>NZ_CP054010.1|WP_050759730.1|951982_952735_-|5'-methylthioadenosine/adenosylhomocysteine-nucleosidase
MKIGIIVAMDKEFAQLKAILSNTETKHFNHKDFVTGRLGEKEIILQQCGIGKVNSAIGAVEMINHYHPDLVISSGCAGGADTSLEVTDVVVATECAYHDAYCGDEVAYGQIIGMPARFKAPTELIEKALSLNNLPDCKDLHVKAGLTVSGEWFVNSREKMQQIMDHFPEATAVDMESCSIAQVCHIYQTPFVSFRVISDVPLKDNKASQYYDFWERIANGSFEVTKQFINLIQNSEFRIHNYDYRGRQSL
>NZ_CP054010.1|WP_004359166.1|951229_951724_-|S-ribosylhomocysteine-lyase
MNSELSKIPSFTIDHERLLRGIYVSRKDEVGGETVTTFDIRMKEPNREPVLHVGAIHAIEHLAATFLRNDDEWKDRVIYWGPMGCLTGNYLILRGDLESKEIVDLMRRTFQFVADFEGEIPGAAPRDCGNYLLHDLPMAKWESRKFLTEVLDNITDANLVYPEK
>NZ_CP054010.1|WP_036885792.1|947335_950245_-|outer-membrane-beta-barrel-protein
MKTFCTALILLCLTVCISAQTLDNTITIEGRVQDFVTHVDVPGCLVEVLNANDSSVVASQKALKEYQSGEQSWKTSEYWITIPRKEGDYILRVTEDGFMPTYVKLPLHHFYKREISREVATIFLKRPKTVDLKEVVVKATKVKFYHKGDTIVYNADAFQLGEGSMLDALIRQLPGAELSKDGRIYVNGKFVESLLLNGKDFFRGDNTVMFENLPTYMVNQVKVYDRLGENSRFLGQEVAGDKKYVMDVQLKKQYNIGWVGNVETGGGTKERYLARLFAMRFTDHSRLAVYGNMNNLNDDRKPGENDNWSPSDLFGGLTQQQLGGLDYNIDARSGKYKLSGNAQVRHADNTIVNNTNRTNFLANGDTYDRIVANNRNHNFTLSTDHQFYFEFKNANLNIKPCFNYQYYNNKSGYSSLTLNRSFTSFSKAQLDSLYTPMIGRELIRTAINRNLRNGLSIGHSLEGSVSMESLIKFKHSPDHVTLYADASLRHATEDSFDRNRIDYYTNGLQSNTDFRNRYFNNRPDHGYSMTGKVTYSYLVKRGLFFDFSYKYNRTTSNRYSSLYRLDQLADWGINSEHELGILPSVEAYNRVMDIHNSYDSRQTDNTHTLGAFLVWNKRTTKSEWWAQLVPNLSLLSRTMHYHSGNVDTTFTKRSILYNMYSTFIKWRSTDHKYEFMFQYHVNGQAPDMNLFVNILNTTDPLNVTMGNTNLKPSYKHELISHFLRIYPKKGLMWLIEAQYIPTVNAIAMGYTYDKATGQRTFRPDNVNGNWHGQLALGGAGPLTKNRKLDFKAMAGLRYEKSVDLIGLAGTSASNRSIVESLNYIGDLQLNYRLGQSSIGFISKGNWAHVDGTREDFEAFNVSDFNYGLTAQLQLPWDFRLGTDLTMYSRRGYLDKSMNSDDLVWNARLSRSFFKGQLTLLLDGFDILGQLNNVTRTMNAQGITETYSNVIPRYVMLHAVYHFNIIPKKK
>NZ_CP054010.1|WP_004359169.1|944423_945404_+|helix-turn-helix-transcriptional-regulator
MTIEFCAINKPEDWMEMVAEQFGTSVINDGFTIPSSIGSGFFKQYYPLPWLTLTYISFVAYEPITMIRRSVENSKWIPVMFYINEHKHEQIIGTSTKTVGVDTLDGIFMPSSSIPTEWSFPPKKRYENITLTFNKDWIEKIDAAHETYIGRLLQSDKAFYLFETITPAMQQVLDNIKSITEIDNPFSTLHLHGKTMELLTMFLEKLEKRSEVKSLANLNLNDVESVFRVRRQILQSLSNVPSIPELAREANMSSSKLQKCFKQVIGKAIAEYALSEKMKWAKRLLSTRLYSVSEVGYKVGYTNLSHFTEAFCKYHRMKPKQYLDSL
>NZ_CP054010.1|WP_004359170.1|943113_944295_+|hypothetical-protein
MNTTIFNRIAFSAMLVGFIGLTSCNKNDEPTPTPQEVQQHFTFVHYVDKSAYVGTFSDLTPQATDNKKAFEFGFGCYLFAKGNTVLVPEGKFGDKIHKFTRGAHGELIKAGTMTFEQMAQPGEINFVDEQRAYVALHGRGKIALINTSTLQKEDEIDLSSYAVQDNNPDPGCNVIRDGKMYVALNQLNSPHTSVPGTGAEVAIIDLKTKKTEVIKDNRTSVVGLFRHSDAFIDERGDIYFYSAGNNFNVADKEGFLRIRKGSDKWDSNYLFNLSKTTIKGIGKTGQYMIKSFYAGNGIVYSCVKVTDTEFGILKKDFQPVKIDIWNKTIEKLDLPMTDSNGSFAITRYKDFIVFGMICNNGTGYYTYNTKTGECSQKPIVTAIGVPSSLVAFE
>NZ_CP054010.1|WP_036885793.1|940719_943095_+|TonB-dependent-receptor
MSISSIVHLYKRMLIVGFLSLWSFPMFAQLQPTEIKVIDAENGNSIEFATVQWKGLNAPTYTNSTTTNRKGIAKLSASSNQKLMLMVSYVGYQTITDTITANGKRYTIRLLPESTELADVVVVGKTRAQILRESPEAVSVINAKELQGRSISLETVLNKTIGLKVGQTGGLGSSSRIIVHGLEGNRIQILWDGIPMSTSDGAFSLDEIPIDIIERIEVYKSIIPARFGCDGLGGAVNIVTKEFSTDYLDASYEFGSYQTHKGSVFSRKNFPKSGILLGAGGYYTSAKNDYSFRVPERENLLVRRDHDHFRSYMLKGKIAFTKLWLDEISTEFGYYNRFNEIQGILKNIQHAENKSGMFMLENKLIKSGMLNDRLNFESHFSLSHTTNNFVDTARVNHDFEGNIYPSPNGQGETGDVPHNSNDKGLEINERINFDYKLSANHSLNLNTLINYARRQPSDNIASQHAGFVIGGFPSKKTSFISGLTWESKLFDKKLTNMLSAKYFHLHSEIEDLTSYEMIEAPKKKNNTTSQIGWIEAIKYEPFRGFHLKASYQRAIRLPNSQELFGDGIITFPAAGLRPEKSHNFNLGFLIDKNDVLGLSRLQFEVNSFYMQVSDMIKLMKQHMAAGYVNAEKVHIKGIETEIKLDISPTVYAYGNLTYQDVRDVLNYLPGTQAPNPTKGLRLPNIPYLFANFGAEYHSNRLFKNWYVKAFWDGKFTEEFFYFWELTELQKRRIPRSFVNDIGLLLTYKSKYSVALECHNIMNKEVWDQFRQPLAGRTLHLKFRYVFSKGIF
>NZ_CP054010.1|WP_004359172.1|938774_940520_-|ABC-transporter-ATP-binding-protein
MDKQKVRPLDEERESRSLLSNAVVILHLILGTLPILLVVWAVDKLINGTLPPIIVWGIGGIMILFAMLRGVFYGTSIWRAHRSAYNALTRLRLRIISHLQRLPLGFFQERKVGDLVNIINHDVEQIEIYLAHGLPEILSATLFPVLLWVIIMVLDWRLGLSLISLLPVAFLLQMAVKTLWGKSFQHFMESTQKMSEDLLEYVATISVIKVFSNEENRTEQVLGGMRDYIRWVKRSMFSVTVPMTLITMFLEGGIVVMTLIGLWMMSSGELTVARFILALILGGLFSSSFAKLATFQHFRIIYGQSLAKVQSITEVQTKETADKKTDTTQTDVCFEHVTFSYPNKKDNALKDVCLQFPRGSHTAIVGESGSGKTTLASLMMGFWHPQTGTIRLGGENIMEFSERNIADYFSMVQQEVFLFNTSIRDNICIGRPTATQKEVEMAAERARIHDFIMGLPNGYDTLAGEAGIKFSGGEKQRISIARMLLKDSPIIILDEATAALDGENEKLIQEALDELQRNKTVITIAHRLNTIQDMERIVVMDKGQVVSKGTHQELMKDCSLYRNMTETQEQVSKWQLKEEEE
>NZ_CP054010.1|WP_004359173.1|937074_938772_-|ABC-transporter-ATP-binding-protein
MVRNILNELTARGVRHLIISALFFVVYALCGTAIMLTVLFLIDRHIQGESISFISAAWLLGGLLVLKTLSNAIADMSKHFAGFDLVERIREKIILKLKMFSLGFYTNERLGEISTVIHKDVDNMEMVVGHLWTRMSADFIVALILGIGLFCVDWRMGLTMVAILPIALFSLYRGIRSGIKAQEESQDNLADMVSLFVEYVKGIPVLKVFGGKGMFRDRLDHSVSEFGESSKNTSRLAAVSVGRYTFLIELAFALMATIGLWWTQQGELSLFAYLMFIIVSKEFYKPFVNMESHWLNYIKVKDSYGRISHLLNAPVITNPEQPKTATHFNLSFDKVDFHYEKEGFEMKNLTFHVPEGTVTALVGSSGSGKTTITSLLLRFWEPQTGSIRIGGIDIREMDYDYLLGKISVVMQNVILFSDTIANNIKVGNQHATQEEIEEAARRAMIHDFIISLPEGYETKIGENGLGLSGGQKQRLSIARAFLKDAPIILLDEITSNVDPVNEYKIQQAMSALIRNRTVLVIAHHLQTIRNANQIIVMDKGRLVENGTHAELAAKNGMYCKLLSMQ
>NZ_CP054010.1|WP_152031158.1|958250_958343_-|smalltalk-protein
MIKPIWKNILHILVTVLTALATTLGVSSCM
>NZ_CP054010.1|WP_004359161.1|958585_959107_-|HU-family-DNA-binding-protein
MSIKFRMYQDNRKNSKRKGYWYARAVSPDLVSVKDLALRISERCTVTEPDILAVISALVFEMNQVLKDGNRVKLDGLGTFRVGIHSQGVQKAEDFNAQRDIYGAHVLFSPTVTIDAMKRRVKTLISGLRIQEAVQYDAPKAAEKAKNKGKKKENKPSAGPEPGEATATTEGHA
>NZ_CP054010.1|WP_004359159.1|959724_960210_-|peptidase-M15
MINDSHSNEIDFEERLSPHFTVGEMMRSGKAVNMGVKNVPEVNPALGEASREEVIANLRELCRCVLEPLRRRVGRVIVVGGYRCEAVNRAVHGAEHSQHLRGEAADIHVTGLEMCRKYAAILAQTDFDQMILEPQDSMIKRWIHVSYKRNGKNRHQILGAK
>NZ_CP054010.1|WP_155812477.1|960753_961314_+|restriction-endonuclease-subunit-S
MRYNGHYKQLPKTWSNPKIKEVFTINPKNKVLDNINAGFVPMVYIDDGYSGAFKYEKRKWNDIKAGFTHFADGDIAVAKISPCLENRKSMILEKLPNGIGAGTTELYIFRSLNINPKYALYCFKSDSFIQQCIGTFNGVVGQQRVARRIIEEIRFPLPPLSEQLRIVTKIEELFSILNIIATELAM
>NZ_CP054010.1|WP_036885791.1|961720_962524_-|tyrosine-type-recombinase/integrase
MVTTFQKHLAKTNLAKNTITSYLWTVDYFLNHYKEVNKKNLLAYKGYLVENFKPQTVNLRLQAINKYLEFTKQEKLKVKFVKVQQKNFLENVISDADYKFLKTKLKTDGYDEWYFIVWFMAATGARVSELLHIKAEHVQVGYLDLYSKGGKIRRLYIPKTLRIEATKWIKEKELSSGYIFLNRFGQRITTRGIAQQLKHFAEKYGLNRDVVYPHSFRHRFAKNFLDRFNDLALLADLMGHESIETTRIYLRRTASEQQKIVNRVVNW
>NZ_CP054010.1|WP_172891299.1|962500_963109_+|restriction-endonuclease-subunit-S
MLLKCCYHITLILNEYRNNNVDYNGHYPKLPKGWCLCKLKNISLIITGSTPSKSNSAYYGGKVPFYKPIDLDAGRFVDSSAEYLSEAGKAISRVVPIGSTAVCCIGSIGKAGYLIKEGTTNQQINCVIPSEAVDSVFLYYLCTSPLFYQELITLSSAVTISIINKSKMENIIVPLPPIEEQKRIVSKIEDLFGFIKTIEESL
>NZ_CP054010.1|WP_172891300.1|963103_964492_-|restriction-endonuclease-subunit-S
MDTKKLRQKILDLAIHGKLVPQDPNDEPASVLLERIRSEKERLIKEGKIKRSRKTTKTTGAACDKQEVPFEVPSGWVWTTLDDLAFYKKGPFGSCLTKSMFVPKSDNTYKVYEQKNAIQKNEFLGSYYISKEKYNELNGFAVQPFDIIVSCAGTIGETYVLSETPEQGIINQALMLIRLHSRCVEDFYLIYFDYILKEEAYKESKGTAIKNIPPFDVLKNFFIPLPPLSEQQRIVEEIERWFKLIEIIEQGKADLQTTIKQAKNKILELAIHGKLVPQDPNDEPASELLKRVNPKAEITCDNGHYPKLPKGWAICRLEDIIEYEQPTAYIVKSTAYSDDYSTPVLTAGKSFIIGHTDETEGIYNKLPCIIFDDFTKDSRLVDFPFKVKSSAMKILQVNKGIDIEYVSQFMSITRLVGDTHKRYWISEYSKLEIPIPPQKEQKRIIRMIHQLFKNLETIEENL
>NZ_CP054010.1|WP_004359151.1|964668_966090_-|SAM-dependent-DNA-methyltransferase
MAKNISTEQALTKEVWKLATTLSGQGIGYTDYVTQLTYLLFLKMDAENVEVLEEASAIPEEYRWGQLKELDGLDLIAQYEKTLNVLSKQDNLIGTIFTKAQNKIDKPVYLKKVITMIDEHQWLEMDGDVKGAIYEGILEKNGQDKKSGAGQYFTPRPLIQAMIDCLQPKIGETVCDPACGTGGFLLAAYDYMKGQSQDKGKLDFLNNKALHGVDNTPLVVTLASMNLYLHGIGTDRSPIACEDSLEKEPETLVDVILANPPFGERTAGSVDINRPDFYVETKNNQLNFLQHMMLMLKTGGRAAVVIPDDILFKDGAHEIVRKKLLTDFNLHTILRLPTGIFYANGVKANVLFFTKGQPTKDIWFYDYRTNVKHTLVTTKLQRHHLDDFVACYNAATRTETYNEETNPAGRWRKYAADDILARDKTSLDITWIKAGGAEEQFTLDELMTNITTQAGNISKAVAELQKLMAGIKE
>NZ_CP054010.1|WP_004359150.1|966091_968800_-|DEAD/DEAH-box-helicase-family-protein
MLPEEKARVIIDSMFEEAGWKVVDRSGYAPNMTAVAIREGLLKGNREADYLLFLNGKAVGILEAKRVEVDINSDVVKEQATLYTRRCPSWCQAWFPKIPLPLAYVANSKEMMFYDTRKSDAAFEYCSKIHSPWEVTKMLGLQDDYVGLPTLSPKGLRGCQYEAITELEKSFRSGESRALMVLATGAGKTYTACLAAYRMLSFTPMRRVLFLVDRNNLGKQAESEFGTFRLTENGDSFNSIFTVNRLKSAKIPNGSSVVISTIQRLFSLLKGEEIEDNDADDGYDEDCVGEFPENPSLPSDFFDMIIIDECHRSIYGSWRSVLDYFSKAKLIGLTATPGPETRAFFNDNIIVNYTLEKSILDGVNVYGRVYRIKTKVTENGGAILENEKVKKVTRYTGKVEVVENKETKNYTREELNKSIINPAQIKLILETYRDAVYTEMFTDPQREANMDYLPKTLIFALNESHATNIVRIAKEVFNREDERFVQKITYSAGDSNELIRQFRNDKDFRIAVTCTLVATGTDIKPLEVVMFMRDVASEPLYIQMKGRGVRTIGDEQLRNVTPNAYSKDCFFLVDAVGVTEHEKTIASPSGAVTKVISLKELLEKITHGNVSDDYLRLLAGRLSRISHKCTESDREKFVSLAHQSMMEIASDIFKAFEDNVLPEYNNVNEPNTERKALVRNIANHPDARDLLLILNAGFIETLMPGEDTLISKGFSKEEAQSTTSAFEDYCQEHKDEIEALRIIYNNQGEPLTYSMLKDLENKLKLANSKFNTSLLWNSYAIINSHRVKHSSTIEEKEALTNIIQLVRYAFHQIEQLESLYPSAKQYFNLWYGQVWRSITAGQIELMRQVLNYIASNGYCTITDIKENDKTQAAQLIRAFGGRDTANEALSSLSQFIIYRKLA
>NZ_CP054010.1|WP_004359147.1|969343_970453_-|HigA-family-addiction-module-antidote-protein
MATRNNRLVPVRAIHPGEILREELQERGIKQKDFAKQIGVQATHLNTFIRGKRNLNDDLAMKLERHLGIPYKTWMNLHSGFIYDSKAVDVKQSEEQEAREYEDTCASIFNLKLLYKKLNLSHLPCIERVTKLKALFAFDLRSSKELSLQVVGLYKHSEKVHIDEKNMQTWLILNWLEISRATIETQYQKGNGLKVASEIAEMANNRTLSAQGIKDCLNKYGIAYLNVEKLDKTPVDAYSTLVDGCPVITVTYRYNDIDKLAFDVLHELCHIERHLSEDNQAFISTEGTLYSKDPREKEANDFARQQLIPDDVWSRIIGRGCKSLLPHKVVNAIAKEAERYGISPSIAVSRYKHDINWYQTSVYKSPKIS

Crispr_ID: NZ_CP054010_8

• CRISPR_ID: NZ_CP054010_8
• CRISPR_location: 1011245-1011352
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_8

Consensus_repeat	Method
TAACAGTAGTAATCATAATTTGTAGTTGACGAGTT	CRISPRCasFinder

spacers of NZ_CP054010_8

>8.1|1011280|38|NZ_CP054010|CRISPRCasFinder
GACAAGTTTACGAGTGAATTGTAGCAATAAACCACAGC

CRISPR arrays and Neighbor proteins around NZ_CP054010_8

CRISPR arrays

The CRISPR arrays of NZ_CP054010_8

>merge|NZ_CP054010|8|1011245-1011352|CRISPRCasFinder
TAACAGTAGTAATCATAATTTGTAGTTGACGAGTTGACAAGTTTACGAGTGAATTGTAGCAATAAACCACAGCTAACAGTAATAATCATAATTTGTAGTTGACGAGTT

>NZ_CP054010|8|8|1011245-1011352|CRISPRCasFinder
TAACAGTAGTAATCATAATTTGTAGTTGACGAGTT	GACAAGTTTACGAGTGAATTGTAGCAATAAACCACAGC
TAACAGTAATAATCATAATTTGTAGTTGACGAGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_147331687.1|1018183_1018414_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359109.1|1003018_1003969_+|D-2-hydroxyacid-dehydrogenase	unknown	unknown	gnl|CDD|240639
NZ_CP054010.1|WP_004378882.1|1012129_1013644_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359035.1|1013631_1014432_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(F)	unknown	unknown	gnl|CDD|366074
NZ_CP054010.1|WP_004359027.1|1016079_1016499_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359024.1|1016691_1017201_-|DUF3408-domain-containing-protein	unknown	unknown	gnl|CDD|378750
NZ_CP054010.1|WP_004359111.1|1001630_1002887_+|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355
NZ_CP054010.1|WP_004359113.1|998488_1000036_+|sulfatase	unknown	unknown	gnl|CDD|293755
NZ_CP054010.1|WP_004359115.1|997254_998085_+|EcsC-family-protein	unknown	unknown	gnl|CDD|378945
NZ_CP054010.1|WP_004359105.1|1005448_1006132_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359101.1|1010704_1011175_-|DUF4065-domain-containing-protein	unknown	unknown	gnl|CDD|226128
NZ_CP054010.1|WP_004359029.1|1015603_1015861_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359104.1|1006128_1007397_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|227274
NZ_CP054010.1|WP_004359103.1|1008219_1009638_+|PepSY-domain-containing-protein	unknown	unknown	gnl|CDD|377164
NZ_CP054010.1|WP_004359107.1|1004232_1004877_+|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl|CDD|225415
NZ_CP054010.1|WP_004359102.1|1009837_1010680_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004359023.1|1017188_1017503_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP054010.1|WP_004359021.1|1017523_1017793_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|378935
NZ_CP054010.1|WP_004359020.1|1018456_1018942_-|DUF1896-domain-containing-protein	unknown	unknown	gnl|CDD|370228
NZ_CP054010.1|WP_004378883.1|1018997_1020281_-|site-specific-integrase	unknown	unknown	gnl|CDD|271185

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_004359109.1|1003018_1003969_+|D-2-hydroxyacid-dehydrogenase	gnl|CDD|240639	cd12162, 2-Hacid_dh_4, Putative D-isomer specific 2-hydroxyacid dehydrogenases. 2-Hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	0
NZ_CP054010.1|WP_004359035.1|1013631_1014432_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(F)	gnl|CDD|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	3.74356e-92
NZ_CP054010.1|WP_004359111.1|1001630_1002887_+|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_CP054010.1|WP_004359021.1|1017523_1017793_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.44659e-08
NZ_CP054010.1|WP_004359113.1|998488_1000036_+|sulfatase	gnl|CDD|293755	cd16031, G6S_like, unchracterized sulfatase homologous to glucosamine (N-acetyl)-6-sulfatase(G6S, GNS). N-acetylglucosamine-6-sulfatase also known as glucosamine (N-acetyl)-6-sulfatase hydrolyzes of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate. Deficiency of N-acetylglucosamine-6-sulfatase results in the disease of Sanfilippo Syndrome type IIId or Mucopolysaccharidosis III (MPS-III), a rare autosomal recessive lysosomal storage disease.	0
NZ_CP054010.1|WP_004359023.1|1017188_1017503_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	1.71189e-12
NZ_CP054010.1|WP_004359024.1|1016691_1017201_-|DUF3408-domain-containing-protein	gnl|CDD|378750	pfam11888, DUF3408, Protein of unknown function (DUF3408). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 128 to 160 amino acids in length.	4.25265e-17
NZ_CP054010.1|WP_004378883.1|1018997_1020281_-|site-specific-integrase	gnl|CDD|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.94466e-52
NZ_CP054010.1|WP_004359104.1|1006128_1007397_-|AAA-family-ATPase	gnl|CDD|227274	COG4938, COG4938, Uncharacterized conserved protein [Function unknown].	2.38093e-12
NZ_CP054010.1|WP_004359103.1|1008219_1009638_+|PepSY-domain-containing-protein	gnl|CDD|377164	pfam03929, PepSY_TM, PepSY-associated TM region. The PepSY_TM family is so named because it is an alignment of up to five transmembranes helices found in bacterial species some of which carry a nested PepSY domain, pfam03413.	6.17418e-08
NZ_CP054010.1|WP_004359101.1|1010704_1011175_-|DUF4065-domain-containing-protein	gnl|CDD|226128	COG3600, GepA, Uncharacterized phage-associated protein [Function unknown].	1.26525e-16
NZ_CP054010.1|WP_004359107.1|1004232_1004877_+|trimeric-intracellular-cation-channel-family-protein	gnl|CDD|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	5.8241e-50
NZ_CP054010.1|WP_004359115.1|997254_998085_+|EcsC-family-protein	gnl|CDD|378945	pfam12787, EcsC, EcsC protein family. Proteins in this family are related to EcsC from B. subtilis. This protein is found in an operon with EcsA and EcsB which are components of an ABC transport system. The function of this protein is unknown.	3.39553e-45
NZ_CP054010.1|WP_004359020.1|1018456_1018942_-|DUF1896-domain-containing-protein	gnl|CDD|370228	pfam08989, DUF1896, Domain of unknown function (DUF1896). This domain is found in a set of hypothetical bacterial proteins.	2.26008e-65

Protein sequences

>NZ_CP054010.1|WP_004359101.1|1010704_1011175_-|DUF4065-domain-containing-protein
MEDVQQIASYISQRYEKEYGRQIDEMKLHKLLYLTQREAIIETGEPLFEDQFEAWKYGPVLYSVHKAFQTDKLHGEMLSEETIGKYKKVFDKVFSSYAPKDSWSLSTLSHGEYSWRKAREGYDPDSACRAKIRVEDICVDAQRIKQRRIMLNILGA
>NZ_CP054010.1|WP_004359102.1|1009837_1010680_-|hypothetical-protein
MKITEEQRKVLDSFSCERLAGKLENMWIVEDFYNSRNPQLEQNLKDKAYEEDENNTTAYYVIKDEEGSVVFYFSLKCGMLYDKIVEADQYQQLQKIYNLLIKKITDKSISEDKKEGFKELLESFRSKKGLTRESLERVFSADEVTIDEIFKGNQRHVGKTYSGVEIVHFCINDGYREKWEALNIPQRLGSIIFWKFIIPQVKCLLEIVGCEYIFLFAADLSEDESLVNYYRELGFTDSLVHHVAIPLYDLACKFMHQETNQLIEKQKKFFEDFNPDFSEK
>NZ_CP054010.1|WP_004359103.1|1008219_1009638_+|PepSY-domain-containing-protein
MKRRTWRKYHKWTGLIISFFLVMFCLSGIVLNHRRCFADINVSRAVLPGRYDFKHWNNGLLRGTLRCKDDKGHDMVLIYGAAGVIRTDTVASIFIDYNQGLPSGADYRQMRGVVQTKNGQVFAASVMGLYQLKPHQGWQSVALPEMDSDDLLSDITTRGDTLVVLSRSYLYYATAPYRQFHKVEIQPAVGDDGKVSLFRQVWLLHSGGLFGTVGKLIVDLIALILIALCVTGVWFWVRPTHAKVLNWHNKIGVFTIVLTLFTAITGWALRPPVMIPLTMNNTYPLPGTVLASDNAWYDCLRMIRYDEQNHDWLLSTSKGFCSLSSLTSKPQPITIAPPVSVMGQTVWQRDESGMWLVGSFDGLFRWNRQAGQIEPYNNMMVAKATIPGTAAAGQMVVGYSSDFTGEECVADYYDGTFFSAQPEELRTMPMSLWSLALEVHTGRIYAGAIGSFLFIFVAGLFVIIALWSGKKS
>NZ_CP054010.1|WP_004359104.1|1006128_1007397_-|AAA-family-ATPase
MKKIIIDIHKFGPLQEVSFQVAPFMVFTGMSKLGKSYANYLVYYLFTKLLAPGEITRLYESLMGKDSSGSFTLSSDLLSTYLHDNVTAFMRALLGDPTIECDVDFLFPEFGESLHVTYQEVAATEEETVKRLGNTLNISINGKESRVNIIINTAFTVGENCHAILFHRLFRNFYAINLIFPPANGALINADYSLTSSINTKGMYGRFLFDNEYCTSIEVTEEQSPYLNQIKKITDGNVVTEEGKEFLVLDGGEHVNMSAAASSIKEISPLLFLLKNHPGANAAICLEEPEAHLHPSMQIQVADLIAECINNGFLFHITTHSDYFMDRLNQLIKLGNIRKKDETTFKEYCTANGLSEKTFLDGDNVKAYFFHRDDETGKVVIEKLPVEEGGIPMKTFYETVEKMRKQDEQIDEMLYSLNASDQ
>NZ_CP054010.1|WP_004359105.1|1005448_1006132_-|hypothetical-protein
MIDFSVLRKCLLQACFFKQHDDGKVTKYEQQKKANKLEQVTYEHAGEIIEIENHLLKKCKDSFNSKLLDCSYQCDCDGIFLLQVGDKDYIVYSEMKSNFDEKAIWQISSSVVRTKLLLSSIKDFGLEKYQELGIIISYPPVEIKIDDNDSFKNNKTKMISTYREAIHRCKKELKKGKKTTVNGSDFSMSDAHIAEQYQPNNMIIKHVEVPGGNTSCSVNIDDLIASL
>NZ_CP054010.1|WP_004359107.1|1004232_1004877_+|trimeric-intracellular-cation-channel-family-protein
MIYTDPHLVRTLQVILEFLGTFAFAISGIRHAAQKHFDWFGGYVCGFAVAIGGGTLRDTMLGVRPFWMANIMYVLCTGLALFLVILSRRWIQRLSNAWFVFDTLGLALFTIAGIQKTIALGHPFWVAVIMGCITGVAGGVIRDVLLNNIPVIFHKEIYAVASVGGGLIYWALFSLGLPLPITVIVTFLAICLIRFIAVGYHISLPTLQDEDEKK
>NZ_CP054010.1|WP_004359109.1|1003018_1003969_+|D-2-hydroxyacid-dehydrogenase
MKIVILDCHAVNPGDLSWEPIKEIAECVIYERTSQEQVVERAKDADGILINKVNITREVLDQLPQLKYIGELATGYNNIDVEAARERGIIVCNIPAYSTDSVAQHVFALLLNATTHVDHYAEAVRRGEWSKQQDFCYWDTPLMELAGKTLGIVGLGNIGQKVAMIAHALGMDISACTSKNSSDLPECIRKTTLEGLLSTSDVITLHCPLTAENTRMINAETLKGVRRGAILINTGRGGLIDEQAVADALESGQLGAYCADVMTEEPPRADNPLFRQPNAFITPHIAWATREARERLMAICVENIKKFIAGEPQNVV
>NZ_CP054010.1|WP_004359111.1|1001630_1002887_+|replication-associated-recombination-protein-A
MEPLAERLRPRTLDDYIGQEHLVGEGAVLRRMIDSGRIASFILWGPPGVGKTTLAQIIANRLETPFYTLSAVTSGVKDVRDVIERAQSGRFFNSVSPILFIDEIHRFSKSQQDSLLGAVEKGTVTLIGATTENPSFEVIRPLLSRCQLYTLKSLEKDDLLKLLHRAITEDVELKKRNIELHETGALLRYSGGDARKLLNILDLIISAESGNDVVITDKMVEERLQENPLAYDKDGEMHYDIISAFIKSIRGSDPDAALYWMARMIEGGEDPKFIARRVVISAAEDIGLANPNALLLANAAFDAVTKIGWPEGRIPLAEVVVYLARSKKDNSAYVGINKAIELVRQTGNLPVPLHLRNAPTKLMKDLGYSDGYKYPHDYPGHYVEQQYMPDELAPPRPSPKGEGESLPQPLRREGSADS
>NZ_CP054010.1|WP_004359113.1|998488_1000036_+|sulfatase
MQNKVLYGLTGAIAMGAVVPAQAQKKPMNIVFIMSDDHSYQTISAYDKRFISTPNIDWLADNGVKFQESFVANSLSGPSRACMLTGKHSHANGFTDNSKTFDGGQQTFPKLLQKQGYQTAMIGKWHLTSLPTGFNYWDILIGQGDYYNPDFLSNGKKIRRPGYVTNIIADMAIDWMENKRDKNKPFCLLMHNKAPHRVWNPDTCDLRLYDDVTYPLPKTFYDDYAGRLAAQKQEMSIIKDMDLVYDNKMADKENEIHTTTGLEQWGRGNYKRMTLSQRAQWDSYYDPIIKKFKEDKLSGKALAEWKYQRYMHDYMRVIHSVDRNVGRVIEYLRQHGLLDNTMIVYTSDQGFYMGEHGWFDKRFMYEESFRTPLLVYYPGGKHGVVKEMVQNIDYAPTFLEVAGAKVPSDIQGRSFLPLLEGKKPANWRQSLYYHYYEYPAEHSVCRHYGIRTKRYSLMHFYNDINAWELYDLKKDPNQMHNIYGKPGTEKLTKNLKKQLLQLQVQYDDPIRNKGL
>NZ_CP054010.1|WP_004359115.1|997254_998085_+|EcsC-family-protein
MKQSDYLMQQYALIKAWENEEPGVVSKTFGKLLSPVGKLISVVVPEKVIESAINAANAAAQYLTDTADVLRDGNVESIEELRTKDLKLCDQMADSVHNWAVGIATAEGVAGGFVGLPGLVADIPFITTLALRTIHKIGVCYGYVADANNEEEEKAFVLGVLATANASTLGEKASFILGLKQISLLIQRNAWKKLAEMGTANLLAKSIVSVRQAAKLIGVNLTKRKASQSIPFIGGAVGAALNASFINDIAWAARRSYQRRWLEDNKVIEPEASVDE
>NZ_CP054010.1|WP_004378882.1|1012129_1013644_+|hypothetical-protein
MIIKRILLIFIILLLLFPTANATILNLVVGDTIYPTRKHVSSLHKTIELDEVQVIGQRKLFSIRKDTTFINTDCLRVRKGANLEDLIRNIPGMEYDKANRQLSFKGKPLNGVNINGETFMGNDIIAALENMPTDAVELLKLYDMLSALEKMTGVDDGADNYVLDIKTKSTYNGSLTGTLTAEHGNRDRRRDEVQGNLFNADGENTSLTLRSDNLSNMNIGGNNFQNILSGNIVKKFGKKITLNASLSLNAFHNGSENHDYDEQYLSSGTKYRESMLLSLSKNHSNAANINLQYNIDKKTLLNISANGNFGRSDNLTDNTTYLYERNTAADTLTSGTLRNNTKSNGKNYHVSADLTRRIGKAGASFTVKATLGGNSNETNNTSLSLTKFHHLRNAVGGDSLLLRNLCQQLPTLRNESRISLQYTHPFGKQLKLQTGYGLHHEEDRNTSNTYDYTIPNRPYIDSLSYENTLSICGQELTLRMDYKGKQWKINSGIDVDHPTLNYEG
>NZ_CP054010.1|WP_004359035.1|1013631_1014432_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(F)
MTKKKLPVRFTGQHFTIDKVLIKDAIRQANISNQDTVLDIGAGKGFLTVHLLKIANNVVAIENDTALVEHLRKLFSDARNVQVVGCDFRNFAVPKFPFKVVSNIPYGITSDIFKILMFESLGNFLGGSIILQLEPTQKLFSRKLYNPYTVFYHTFFDLKLVYEVGPESFLPPPTVKSALLNIKRKHLFFDFKFKAKYLAFISCLLEKPDLSVKTALKSIFRKSQVRSISEKFGLNLNAQIVCLSPSQWLNCFLEMLEVVPEKFHPS
>NZ_CP054010.1|WP_004359029.1|1015603_1015861_+|hypothetical-protein
MNSAYNKKGDEEFTSQQDILFPKVFDVDGMRVFIYWKLPHPVEKLYPYVDYKIRKISKDTLVIGDYTDFVFVNGHGNAPNRELSK
>NZ_CP054010.1|WP_004359027.1|1016079_1016499_-|hypothetical-protein
MKKQKQKKPDGRCATCPRWDRWHIRIPNSEDQQKLIRLYRKSGAKTKSDFVRARLLGESFKVITQDPAKEPYLEKLSEIVALAHKIGVLYNEVVKVLNTYHSVATAQQLLGKLETYSQILIRLQQQAVQLTKSFGSREE
>NZ_CP054010.1|WP_004359024.1|1016691_1017201_-|DUF3408-domain-containing-protein
MARIDEKRKQRLEQAIRDMGNYGVKLRKPEELPDFDQPFDYEEEKRRFEPVDKVEEQNDKESNKDFSQPSYQETALSPTERATSTEEFHQRMGKTKDRKQLSEFQGKYLQPFRNSHRKAVYVSEETQRKLDFVVRRIGEHGASVSGYVEQVLREHLDQYKEDVERWRKL
>NZ_CP054010.1|WP_004359023.1|1017188_1017503_-|helix-turn-helix-domain-containing-protein
MAENEIITREDPQMQLFSQLMEGTLKKLERYCSTARPMLNGEVYLSGEEVCSQLRLSTRTLQEYRNSGTLPFYKIGGKILYKQSDIQAMLEKHYNPIPKKLWQE
>NZ_CP054010.1|WP_004359021.1|1017523_1017793_-|helix-turn-helix-domain-containing-protein
MKLIIIDRKAWERHRSEFADFIHRVEKLIGNPPKTEQWLDNEAVCKRLGISKRTLQSYRDTGKIPFSMIGHKCYYKQTDICEMLNAVKD
>NZ_CP054010.1|WP_147331687.1|1018183_1018414_-|hypothetical-protein
MQRYNGSLSALTRSSPADGEKNLHRRISLFQGGIAIFYIHAVVFISPNLAGLGCRREYRHDKNTAYSGSLDARRNN
>NZ_CP054010.1|WP_004359020.1|1018456_1018942_-|DUF1896-domain-containing-protein
MKQKNKKELSYFRLKLRSYMSEHHPEKLQDTEFITARADMALTVYCDAVAQGFTHIEAESMASEALYQGLHFSKYDTLISVLENEFERELPAPLPEKLVPILLSNKAVQATFDKFGLTDTLASDEQYGRLYTELTGTIVLLIESNNLPTVRLTEEASLKAL
>NZ_CP054010.1|WP_004378883.1|1018997_1020281_-|site-specific-integrase
MKSTFAILFYIDRSKTNEDGLCVIRCRITCNGTSSSFSTQLQTSPDEWLARKGCIKATTGNSSGINLQLNSIEECLHSLYERTLREENYITAEYLKERYMQQSRPMPTLTELYQSVCEYKEELQGRTLSKATVRAFKDSYKSFVHFLQVRDRADCMPTEVDKTLLEDYRLFMLRDLGNKESSVGNRLRHLHQVIRKALQERYVREDPFELIDIETPTYERNALTADDLQKLLAYRPHRSTDNHCRLIFLLGCFTGLAFSDLKKLRMDDVYTFGDGRRYISLCRTKTQNRSIVPLLPVAEKILAIVSHGRREGLFFREFPSNSNFNRTIQEICIKAGLPPHTQATSHTARHTFATTICLENGLPIETVSKMLGHRFISTTEIYARVTKSKIAKEMQPLMGSEHTRVLRKALRLCPSRTPKKSSPIIGM

Crispr_ID: NZ_CP054010_9

• CRISPR_ID: NZ_CP054010_9
• CRISPR_location: 1094732-1094851
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054010_9

Consensus_repeat	Method
TTAAATGGAGTTAAAGGAGTTAAGACAACACCG	CRISPRCasFinder

spacers of NZ_CP054010_9

>9.1|1094765|54|NZ_CP054010|CRISPRCasFinder
CTGACTCATAGATTAGACGCAGAGTTAAGGAGGAAATGACGAGGAGTTAAGGAA

CRISPR arrays and Neighbor proteins around NZ_CP054010_9

CRISPR arrays

The CRISPR arrays of NZ_CP054010_9

>merge|NZ_CP054010|9|1094732-1094851|CRISPRCasFinder
TTAAATGGAGTTAAAGGAGTTAAGACAACACCGCTGACTCATAGATTAGACGCAGAGTTAAGGAGGAAATGACGAGGAGTTAAGGAATTAAATGGAGTTCAAGGAGTTAAGACAACACCG

>NZ_CP054010|9|9|1094732-1094851|CRISPRCasFinder
TTAAATGGAGTTAAAGGAGTTAAGACAACACCG	CTGACTCATAGATTAGACGCAGAGTTAAGGAGGAAATGACGAGGAGTTAAGGAA
TTAAATGGAGTTCAAGGAGTTAAGACAACACCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054010.1|WP_004360583.1|1077673_1078105_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NZ_CP054010.1|WP_004360589.1|1085726_1089218_+|glycoside-hydrolase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379625
NZ_CP054010.1|WP_036886509.1|1089357_1093119_+|DUF4981-domain-containing-protein	unknown	unknown	gnl|CDD|236673
NZ_CP054010.1|WP_036886472.1|1079521_1079701_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004360597.1|1102075_1102939_+|leucine-rich-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|275383
NZ_CP054010.1|WP_004360593.1|1097127_1097706_+|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl|CDD|271355
NZ_CP054010.1|WP_004360599.1|1103616_1104816_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004360592.1|1095448_1097065_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|237894
NZ_CP054010.1|WP_036886477.1|1080662_1082375_+|family-10-glycosylhydrolase	unknown	unknown	gnl|CDD|224563
NZ_CP054010.1|WP_036886469.1|1078116_1078929_-|GSCFA-domain-containing-protein	unknown	unknown	gnl|CDD|378080
NZ_CP054010.1|WP_004360598.1|1103290_1103473_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_004360585.1|1079026_1079458_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|223979
NZ_CP054010.1|WP_036886481.1|1107055_1108135_-|DUF4876-domain-containing-protein	unknown	unknown	gnl|CDD|379795
NZ_CP054010.1|WP_036886479.1|1082684_1083311_-|hypothetical-protein	unknown	unknown	gnl|CDD|276809
NZ_CP054010.1|WP_036886512.1|1100829_1101732_+|Abi-family-protein	unknown	unknown	gnl|CDD|377910
NZ_CP054010.1|WP_004360600.1|1104956_1105553_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054010.1|WP_155812508.1|1093467_1094694_+|MFS-transporter	unknown	unknown	gnl|CDD|340952
NZ_CP054010.1|WP_004360594.1|1097720_1098884_+|molecular-chaperone-DnaJ	unknown	unknown	gnl|CDD|237660
NZ_CP054010.1|WP_004360595.1|1099199_1100492_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl|CDD|273659
NZ_CP054010.1|WP_004360588.1|1084177_1085473_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054010.1|WP_004360583.1|1077673_1078105_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	9.20782e-21
NZ_CP054010.1|WP_004360589.1|1085726_1089218_+|glycoside-hydrolase-N-terminal-domain-containing-protein	gnl|CDD|379625	pfam14498, Glyco_hyd_65N_2, Glycosyl hydrolase family 65, N-terminal domain. This domain represents a domain found to the N-terminus of the glycosyl hydrolase 65 family catalytic domain.	3.77894e-50
NZ_CP054010.1|WP_036886509.1|1089357_1093119_+|DUF4981-domain-containing-protein	gnl|CDD|236673	PRK10340, ebgA, cryptic beta-D-galactosidase subunit alpha; Reviewed.	0
NZ_CP054010.1|WP_004360597.1|1102075_1102939_+|leucine-rich-repeat-domain-containing-protein	gnl|CDD|275383	sd00036, LRR_3, leucine-rich repeats. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	1.40068e-38
NZ_CP054010.1|WP_036886477.1|1080662_1082375_+|family-10-glycosylhydrolase	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	8.48297e-47
NZ_CP054010.1|WP_004360592.1|1095448_1097065_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NZ_CP054010.1|WP_004360593.1|1097127_1097706_+|nucleotide-exchange-factor-GrpE	gnl|CDD|271355	cd00446, GrpE, nucleotide exchange factor GrpE. GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.	2.16859e-44
NZ_CP054010.1|WP_036886469.1|1078116_1078929_-|GSCFA-domain-containing-protein	gnl|CDD|378080	pfam08885, GSCFA, GSCFA family. This family of proteins are functionally uncharacterized. They have been named GSCFA after a highly conserved N-terminal motif in the alignment. Distant similarity to the pfam00657 lipases suggests these proteins are likely to be enzymes.	1.46916e-90
NZ_CP054010.1|WP_004360585.1|1079026_1079458_+|NUDIX-hydrolase	gnl|CDD|223979	COG1051, COG1051, ADP-ribose pyrophosphatase [Nucleotide transport and metabolism].	2.78328e-36
NZ_CP054010.1|WP_036886481.1|1107055_1108135_-|DUF4876-domain-containing-protein	gnl|CDD|379795	pfam16215, DUF4876, Protein of unknown function (DUF4876). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 392 and 433 amino acids in length. There is a conserved NNS sequence motif.	1.74413e-18
NZ_CP054010.1|WP_036886479.1|1082684_1083311_-|hypothetical-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	6.77045e-10
NZ_CP054010.1|WP_036886512.1|1100829_1101732_+|Abi-family-protein	gnl|CDD|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	4.89924e-56
NZ_CP054010.1|WP_155812508.1|1093467_1094694_+|MFS-transporter	gnl|CDD|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.00263e-68
NZ_CP054010.1|WP_004360594.1|1097720_1098884_+|molecular-chaperone-DnaJ	gnl|CDD|237660	PRK14289, PRK14289, molecular chaperone DnaJ.	0
NZ_CP054010.1|WP_004360595.1|1099199_1100492_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl|CDD|273659	TIGR01499, Folylpolyglutamate_synthase, folylpolyglutamate synthase/dihydrofolate synthase. This model represents the FolC family of folate pathway proteins. Most examples are bifunctional, active as both folylpolyglutamate synthetase (EC 6.3.2.17) and dihydrofolate synthetase (EC 6.3.2.12). The two activities are similar - ATP + glutamate + dihydropteroate or tetrahydrofolyl-[Glu](n) = ADP + orthophosphate + dihydrofolate or tetrahydrofolyl-[Glu](n+1). A mutation study of the FolC gene of E. coli suggests that both activities belong to the same active site. Because some examples are monofunctional (and these cannot be separated phylogenetically), the model is treated as subfamily, not equivalog. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	8.36744e-124

Protein sequences

>NZ_CP054010.1|WP_155812508.1|1093467_1094694_+|MFS-transporter
MMKQKTNYLFPLAIIGLFFFSIGFALGINSYLMPVLEKSMHISGAASSLLLAATFIPFLLFGIPATHCIKAIGYKRTMALSFAIFAAAFGLFILAAKQNSLTWFLIASFVSGAANAVLQASVNPYVTILGPMDSAARRISCMGISNKLAWPVTTLFITLVIGKGIGDTQLTDLYMPFTIIIGIFLLLGVIALMAPLPDVKAAGEDESENGDETAVSSYADGKTSILQFPHLLLGCLALFLYVGVETISLATATGYAKSLGLEGDNYGFIPSVGMIVGYICGVIFIPRYLSQAAAMRICAIIALVGSVAVAVVPDPVISVYCIFLMALGCSLMWPALWPLAMADLGKFTKSGASLLTMAIAGGAVMPWLRGVVQDATSFQTSYWVSVPCFLFILYYGLAGYKIRTKKEE
>NZ_CP054010.1|WP_036886509.1|1089357_1093119_+|DUF4981-domain-containing-protein
MLRAGTWGAKPEHGKTYLISVGQDTKNVLTPYKYSWLRDTGLAFLTYAEGNDAQKWKLIAVSGKQDCYQLVNGDGELAFDMALNEEKKVSGYPCMWTQSIANPNQQIYITKKGSGYKLSAVSARNGQTYYVTFGSISSVNGYYCGYENSEASAATLQFKEVPAVVIPEGADWENAKVYERNKERAHATYMPYPSTKAMKADAQRYDKPWLDPTGANYLSLNGTWKLRWSEGAKPVLLGKDDFWGDGVSTEGSAWNDITVPSCLEMNGYGLPMYVNVDYPFEDQQPYVRMKGDLKNSVGSYRRDFTLPAGWENKRVFLHFDGIYSAAYVYVNGNEVGYTEGANNVSEFDITKYLHTGKNNVAVQVIRWSDGSYLEGQDMWHMSGIHRDVYLVATPKTYLADHYIKSTVTPGATTAAMGSAATSVDLTVCNRDKTAAQKTVTVTLFDPSGKEVKKLKSDFVFAAGDSLKTQTVDFGTLSNVKLWSAETPTLYTFTFSQSQDGKEEEAFSTKYGFRKIDLSKGYLEVNGRRTYLKGANTQDTDPLHGRSISTDLMLKDIAMMKQSNMNTVRTSHYPRHAKMMAMFDHFGLFVVDEADMELHRNWEGSKTIINNTDWTGAIVDRDVRNTLRDRNHPSVVFWSLGNESGSGLNIMAAYNAVKELDNRYIHYEGSTRDKAEGTDIHSVMYPAMDAWRSGTTGPVTSDVNHPNTNKPYFMCEYAHAMGNAVGNLREYWEAMEGSQMGVGGCIWDWVDQSIYSYDAIKNNQLTKNGFPAYITGYDCPGPHQYNFVNNGLVNADRAWSAELDEVKRIYQWVGFDLNKDSRQVKLTNKYLDRNLNQFYLKWTLLADGKPVQDGIVKKLNCAAGGTETIDLKYSPTAFAGKELFLNIGLYTKEETNWCDRDYPVAEFQQQLAQRTEVLDKVDNTKADALHATKNSDGGYTYANSKQKVTFDGQGNITLWSYDGKNLFMPEAGPRFDRYRWIENDGPMEAYGNAATDNGVTSQTATFQLSDDGKTATVNVTQNGNYGKATYKYTINANGTIDLASSYEAQGNGARRLGFSLNFPSDMSKVRYYARGPRASYIDRLDGEDFGLYETTVKDMYEPFAHPQSNGNRVGLRWLTLTNNEGTGVKVETAGDVAFSLTPWTDAELRTARHEWELPTSNRTVAHFDAIQRGLGNGSCGPGPLPQYEIQKGKTYSNIVRFIPFSEAADDTANGISAVVNSATTIAQVYDLSGRKLPEPPAKGFYIQGGKVHVN
>NZ_CP054010.1|WP_004360589.1|1085726_1089218_+|glycoside-hydrolase-N-terminal-domain-containing-protein
MNICKRLCAAFLLSVVCVGQVYAQGYPRISTKGNEHWYYVKYLRSNNVLEDKGEKQKCLTAVPQVMNGDRQLWKVVAAENFGRNKKYQLVSKSGRTLYVNGTNPYSSRFMAATKATDITSFHIFQSMNNSFGTGAFELAPDSTGSHVMNQVGEIRAGQEIGLWDKGDINNVLTFVSKDDMEFPYYMPVISTAANPVYYYIQFQTGNWLLSAKGDKATCQTASLHNGNLDDMLWRVSEKDGKYAFVSKSGKILYISDSYVNAAKARNVKDTLFTMVESNNALGGFEIGKSTTGRNFFNMFQGAGEGKLISFWDLGDGGNVVRFVPAEELVPVSGIATFNPANKYTLWYTKPATNWMTSCLPIGNGQFGATLMGDVAIDDVQFNDKTLWSGKLGGLTSTAAYGYYLNFGNLYIRSRGMSKVTDYVRYLDINDAVAGVRYTMDGVAYSRTYFASNPDSCVVVRYTASQNGKINTTLTLKNQNGRNVSYTVDNNNQATITFDGQIARQDDHGATTPESYYCVARIVTDGGTITKNAKGVIEVNGANSMTVYLRGLTDFDPDAPTYVSGANLLAARAAATVNGAQNKGYDALFAAHKTDYKSLFDRCQLTLGDVKNNIPTPQLISSYRNNQHDNLFLEELYFNYGRYLLISSSRGISLPANLQGIWNDNNTPAWHADIHANINVQMNYWPAEPTNLSELHRPFLDYIYREACVKPTWRRFAPDMGHVNTGWTLPTENNIYGSGTTFANTYTVANAWYCQHLWQHYTYTMDKDFLRTKAFPAMKSAVDYWFKKLVKAADGTYECPNEWSPEHGPTENATAHSQQLVWDLFNNTRKAIKVLGDDVVSKAFRDSLATYFAKLDDGCHTEVNPADGQTYLREWKYSSQFNNPSKIGVNEYKAHRHISHLMGLYPCTQISEDADKTVFEAARQSLIARGDGHGTGWSLGHKINLNARAYEGLHCHNLIKRALQQTWDTGTNEAAGGIYENLWDAHAPYQIDGNFGYTAGVAEMLLQSHNDKLVILPALPTTFWQKGSVKGLKAVGNFTVDIDWAAAKATKVQIVSNMGITCIVKYANVAKEYKVTTADGKTVKAKRISDDEISFPTVKGGVYFIVSKTADAIAAVQKAQDGNIASVDYYSLNGTKTSQSRSRGVYIKQMKYSNGTTSTTKVIN
>NZ_CP054010.1|WP_004360588.1|1084177_1085473_+|hypothetical-protein
MKKFFTLLSLCMVAMTTFAQWVSVPESGEKYYIAVGNQKVGYVTANGDGEKLTAKAASLGDAEKQTWTCTKNADETWTFTVTVDGNTWTMYTNAGERLAAGSDTGENFKAFKIIDHNDDPSAAFGAIKMLEKDGNAFVNIYSGQKLGNEYGPWTETDNGSKVYFIKASEVEIPHWDFDFSTFRQGDNSTRYFIQFNRPAANNPTYGPTGLAGVTGNKLMLSVDKDTLIADSLIKGDVNFRYKVWHITDFDADSKKIVLVNEAGQYIKYTDLATEMSGGNDMYKKNEAGEWVRNGKSGGGKMTGAFMATTDPQELYIFESNQGSECYSIGDSNDKESQNFLNVWGNVGWHHFMGKWKVNDINNALKLIPINEVLSDDEIAEMDAATGISNVRVQEKQADGYVYTLDGRMVAKSLNGLAKGLYIVNGKKVVVK
>NZ_CP054010.1|WP_036886479.1|1082684_1083311_-|hypothetical-protein
MNRNFLLALSLFMFLTLTSCNAQRNEKLCCGHKPDPAVIELHNQAVNAYTNHSNSPDSVKKAMTLLDCAIDKDPDYQLAYAHKAEYLKNQGDLIQALETLNAYLKRNPTEPYTLLGAGMFYEKLGNKKEAMDYYKRAEVNFKRLYEKDNDSAHEINRCFAIRLMEGPKKAKALYEAERDRLASTEEQRKINDVLVMSIIETPREQFFK
>NZ_CP054010.1|WP_036886477.1|1080662_1082375_+|family-10-glycosylhydrolase
MKKLFLFTLLCVITMTTQAQTNLSDYLTKRMPKRETRAVWLTTLANLDWPKNYARSEESIKLQKQELIDILDKYQKANINTVLLQARVRAATIYPSDIEPWDQCITGVEGRAPGYGYDPLGFAVEECHKRGMEIHAWIATIPVGAKNSLGCRTLMKKGFRIRNFSTGSYLDPADPGVAPYLASICGEIVRKYDVDGINLDYIRYPDGWPRPSYRDGDTPDQRRSNITAIVRAIHDEVKAIKPWVKMSCSPIGKHADLSRYSSKNFNAHDRVSQEAQEWMRLGLMDQLYPMQYFRGDNYYPFVADWVENAYKREIVTGLGTYFLDPREGNWTLGDLTRQMYVSRDLGVGHAHFRSYFLTANKQGVYDFEKQFNATLSLPHKMQGVASTAAMPYAVNSSLVERREDKSVILRWKAVTPYYNIYASYTYPVDTEDARNLLFVRYTGQTLQLKNVNPNLYFAVRGMDRYGLETPALQENMKSTMLSKSPVSLLANDGNTLTLPAAAKLTDADRYVILSLQGVILRIINAKSVRNNQLYIGSLSDGMYSLKVYNHKKKSFMLGSFMVKRASKLMS
>NZ_CP054010.1|WP_036886472.1|1079521_1079701_-|hypothetical-protein
MRRTILILLLFIIGNGLLLLGIDFKPTIPIIIVQIMSLWGTYKLIKDSNLSKKKEEKSA
>NZ_CP054010.1|WP_004360585.1|1079026_1079458_+|NUDIX-hydrolase
MYTYNYPHPAVTADCLVFARTDEGMKLLLIQRKNEPCKGKWAFPGGFMDIDETTVDAARRELKEETGLVVGELHRVGIFDAVDRDPRERIITVAYYTILDKPAEVSGLDDAAQAKWFLLTELPDLAFDHKEILQEAERVLGDG
>NZ_CP054010.1|WP_036886469.1|1078116_1078929_-|GSCFA-domain-containing-protein
MEFRTIVNIPRPTFELEPCERILFVGSCFADNIGKRFEEEKFRAMVNPFGVMYNPVSVLHTVKKVANHTFDTAVFTLGTNHVYVERATGEIVDNCQKRPQREFEERELTVEECADTLSEAITLLRQANPKVNVIITVSPIRYAKYGYHGSQLSKAVLLLATDKVIKEEGERVYYFPAYEIVNDELRDYRFYKADMLHPNEQAVEYIWEQLVATCFSAEAKQFLKEWLPIKEALAHRPFNPEAAAYQDFIKKTKEKAKMLELKYPNIELNL
>NZ_CP054010.1|WP_004360583.1|1077673_1078105_-|transcriptional-repressor
MNDKQIEALLKAHGIRLTANRILIARTLSGLDNPASMKELEAKIQTIDKSNIFRTLSLFKQQHLVHQLEDGNDIVRYELCLSDDDEEDEDMHVHFYCERCHRTYCLNDIHVPQVDLPAGYEQSSINYMIKGVCPKCAHRYYIK
>NZ_CP054010.1|WP_004360592.1|1095448_1097065_+|ATP-binding-cassette-domain-containing-protein
MITLSNLAIQFGKRVLYKDVNLKFTPGNIYGVIGANGAGKSTLLRAISGDLEPNKGTVELGPGERLSVLEQDHFKYDEYKVMDTVLMGHDALWQNMKEREELYAKPEMTEEDGNRAADLELKFAEMNGWEAESNAAQLLQNLGVKEDLHEKQMSQLSNTEKVRVMLAKALFGKPENLLLDEPTNDLDLETVEWLEDYLGEIDEHQTVLVVSHDRHFLDSVSTQTIDIDFGKVTVFAGNYSFWYESSQLALRQAQNQKMKAEEKKKQLEEFIRRFSANVAKSKQTTSRKKMLERLNVEEIRPSSRKYPGIIFSMEREPGNQILEVENLKAVDEDGTVLFDNVNFNIEKGQKVVFLSRNSKAMTALFEIINGNREPDAGTYNWGVTITTAYLPLDNTEFFDCDLNLVDWLSQFGPGNEVAMKGFLGRMLFKQEEVEKKVNVLSGGEKMRCMIARMQLQNANCLILDTPTNHLDLESIQAFNNNLIGFKGNILFSSHDHEFINTVADRIIELTPKGTIDKLMSYDDYIHDEQIKEQKAGMY
>NZ_CP054010.1|WP_004360593.1|1097127_1097706_+|nucleotide-exchange-factor-GrpE
MSKKEKNIKIEGEELELNNEETTQNDAEAQAEETNGKETPAEEELDPLTAAQNEAEQWKDKYIRLVAEFDNYKKRTLKEKSELILNGSEKTVAAILPILDDFERATADKTEDPQAIKEGYELIYKKFLKALETLGVNKIKTDNADFNVDYHEAIAIVPGMGDDKKGKVIDCVQTGYTLNDKVIRHAKVAVGQ
>NZ_CP054010.1|WP_004360594.1|1097720_1098884_+|molecular-chaperone-DnaJ
MAKRDYYEVLGVSKNASEDEIKKAYRKLAIKYHPDRNPDDPEAEAKFKEAAEAYDVLHDPQKRQQYDQFGFDAPGGGFGGGSPFGGAGGFSMDDIFSMFGDVFGGRGGGFGGFGGGGHQAPKYRGTDLRLKVRLSLQEVATGVTKKFKVRKDVPCEHCHGSGAEEGSGTETCQNCHGSGVEIRTQQSIFGMMQTQTTCHVCNGEGTIIKNKCTHCHGEGVVKGEEVVEINIPAGVAEGMVVNVPGKGNAGRHNGVAGNIQVYIEEEPNDTFVRDGQNIIYNLLLDFPTAALGGQVDIPTIDGSNVKIKIEPGTQPGKTLRLRGKGLPAVQGYGSGTGDLVVHISIYVPKELNKEEKKIIEDLRQSENFRGDNSTKRSIFENFKKLFC
>NZ_CP054010.1|WP_004360595.1|1099199_1100492_+|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MNYQETVEYLFNSTPVFEHVGASAYKEGLETTKALDEHFGHPHTHFLSIHVAGTNGKGSCSHTLAAILQAEGYKVGLYTSPHLVDFRERIRVNGEMISEQEVIDFVEQERNFFEPLHPSFFELTTALAFKYFAEQKVDIAIIEVGLGGRLDCTNIITPILSIITNISLDHTQFLGNTLAAIAAEKAGIIKHRVPVVIGESVPETQIVFKAKAQKEDALIVFAEDIPAVLSSRPNPDGSIAYQTRFFGDFVGELGGSYQEKNANTVLTAVMQLYNKGVIKNAESIAKGFANVCELTGLMGRWQKLQANPLVICDTGHNVGGWTYLSQQIKRQQCKQKRIIFGMVDDKDLHAVMSMLPDDAIYYWTQPSTHRAFPAEKVAATADDYDLHGKVFPTVLEAYQAALHDAAQSDFIFVGGSSYVVADLLTSLQKK
>NZ_CP054010.1|WP_036886512.1|1100829_1101732_+|Abi-family-protein
MVNLIPFTKRFESSENLVDLLESRGLQICDRNKAIQYLDNIGYYRLSAYMYPLLKMPKTAHLYKKGSSFKKVMMLYRFDKKLRLLMFNEIEKIEIAIRRAVMQITADMTGNPFWLTDFSYFLDGFKFNETMRAISKEYSKSKEEFILHFKRTYSEPYPPSWILGELLTVGNVNAIYRNIKQNRIRKRIAKRFGLPINVFESWLTVIAVTRNACGHHSRVWNKQNAIQPAIPISPAGEWIALPTDSMRAYFDLCIIKYFLNVISPNNDMQSKLTWLFIRFPEIDLKALGFPQGWETEPLWR
>NZ_CP054010.1|WP_004360597.1|1102075_1102939_+|leucine-rich-repeat-domain-containing-protein
MKQIYILLIALLMGLSANAETSGTCGPNLTWHLTDDGVLTISGKGEMYDYSYRNEAPWGKYNINRIIKRIIIGDGITTIGSSAFDRCFFLTSVTIPNSVTTIGGFVFSGCSALTSVTIPNSVTEIGDYAFTDCRSLTSVTIPNSVTTIGGCAFRVCTNLQKVNIGNSVKTIGTSAFDYCTSITQISSEAVVPPTCGINALNGINKSKCKLIVPKNSLDAYKQAYQWEDFFLIEGSTTGITNTVYNKAGLADVYTIDGTKRLSKASTDEINALPKGVYIVNGKKIIIK
>NZ_CP054010.1|WP_004360598.1|1103290_1103473_+|hypothetical-protein
MVKLKYKGRNMNVAMIIIFALILFIYEDAFGPLKKGNTQYYVSSGIGIWGGKFRIETRTE
>NZ_CP054010.1|WP_004360599.1|1103616_1104816_+|hypothetical-protein
MAYLEKNYPGQRIVLSDKYETSRGLSNDIRIWTFTLSDYPKDTFHVASNISSYPFPMMKNQIGIIDDFEKVVILRRAKEFEHGPMKNFDALTRRLWAHFPELDFSLKPAKLELRTVDDIWRAKHLIDAFDQFLGDERLTEEVQYYLRMYMQGPCYDLNHGGSVAPSDNIAIDKSGKKKGCYIERRFCFGVNRQELCQQFYNDVMEFHQLMDSYGNGVNKETFQAWAENQLRLVKPLLDLPSEEKRDSLLKLLGVRHDYTGSIFIDTGMKPYMLVTLSEKEEGSGSYNLFFTYPQLHAFCLRSGLQVQGTGDHFRVKGVDGRHYEFSSQFYKEKKGAIGFDEDVCYFLRNGRKVLVKGFYTPYECISDVLVRQITGRDVKKMVVSGQISLNGQTFGRGPN
>NZ_CP054010.1|WP_004360600.1|1104956_1105553_-|hypothetical-protein
MKRLALYFVGLVCILCNCTAQTVSSSAKDNSQQNQNKQLQQNVKGQESAPTYSIISVENTYKLRWTGKAFTGLHKDKANTWLIKAVVKGLDAKWLKHPFSITTKDVWLLKDSLQKDVVAIVALESAEAGWSFPTINKEYFMIEECEAPLYAVPYFINGRVYIICLTPSFQIKGDEMYPTIDRKELQEKVLIPLMQSFK
>NZ_CP054010.1|WP_036886481.1|1107055_1108135_-|DUF4876-domain-containing-protein
MMKKKITAYLLLSLMLLGLNSCTRNEMPVKQSTSKTKLDHLIIKEVFYVGHYWYRDVRAWGMKNLNQMYNDDQYIAIFNPTDEVKYLDGLALCVNAIEPSKAIQFAPKDDFVNRYYGASGISYFPGKGNDYPVKPGQTIIVAKYAIDHKAKFEAELEGEDLSMYGGLNAFLDLSKADFEWTNSNYDPGQKNNPNVPDMNAILTSTDASGNIGPAYEFSHISESNGIALIKLPWTPEEFKKNYAETKDSKGYLHYITVTSSAFGDFYAIEIPFECVIDCITICPRRMFQMRPSKLDRGYNAVTDVSFSSLKQSDYPISSGLALIRKWDGKKYVDDNNTTADFEVKVASLSRRDEKGNAIK

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP054010_1	1.26|11410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11410-11439	30	NZ_CP054010.1	621209-621238	0	1.0

1. spacer 1.26|11410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to position: 621209-621238, mismatch: 0, identity: 1.0

ctgagcaccagctaaaggctgcgaaatggg	CRISPR spacer
ctgagcaccagctaaaggctgcgaaatggg	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	MN693375	Marine virus AFVG_25M113, complete genome	28612-28641	4	0.867
NZ_CP054010_1	1.2|9564|29|NZ_CP054010|CRISPRCasFinder,PILER-CR	9564-9592	29	NC_011246	Borrelia recurrentis A1 plasmid pl124, complete sequence	6246-6274	5	0.828
NZ_CP054010_1	1.2|9564|29|NZ_CP054010|CRISPRCasFinder,PILER-CR	9564-9592	29	NC_011247	Borrelia duttonii Ly plasmid pl165, complete sequence	44720-44748	5	0.828
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP053834	Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence	71237-71266	6	0.8
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP010110	Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-4, complete sequence	53467-53496	6	0.8
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	MN698243	Pelagibacter phage HTVC104P, complete genome	10291-10320	6	0.8
NZ_CP054010_1	1.9|10102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10102-10131	30	CP024688	Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-4-144K, complete sequence	49243-49272	6	0.8
NZ_CP054010_1	1.12|10333|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10333-10362	30	NC_023007	Bacillus phage vB_BanS-Tsamsa, complete genome	130167-130196	6	0.8
NZ_CP054010_1	1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10487-10516	30	AP014234	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C93-MedDCM-OCT-S32-C16, *** SEQUENCING IN PROGRESS ***	18783-18812	6	0.8
NZ_CP054010_1	1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10487-10516	30	AP014235	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C93-MedDCM-OCT-S38-C9, *** SEQUENCING IN PROGRESS ***	20782-20811	6	0.8
NZ_CP054010_1	1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10487-10516	30	MH579717	Pelagibacter phage HTVC021P, complete genome	13500-13529	6	0.8
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	NZ_CP046318	Campylobacter coli strain FDAARGOS_735 plasmid unnamed1, complete sequence	35603-35632	6	0.8
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	NZ_CP011016	Campylobacter coli strain FB1 plasmid pCC42, complete sequence	18388-18417	6	0.8
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	NZ_CP040242	Campylobacter coli strain S9 plasmid pCcS9_3, complete sequence	17119-17148	6	0.8
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	NZ_CP028188	Campylobacter coli strain CFSAN054106 plasmid pGMI16-001, complete sequence	6530-6559	6	0.8
NZ_CP054010_1	1.23|11179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11179-11208	30	MG065692	UNVERIFIED: Campylobacter phage C13, complete genome	46014-46043	6	0.8
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	MH598807	Pelagibacter phage HTVC120P, complete genome	38213-38242	6	0.8
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	MN693171	Marine virus AFVG_25M555, complete genome	25683-25712	6	0.8
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	AP013400	Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S30-C37	34601-34630	6	0.8
NZ_CP054010_1	1.3|9640|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9640-9669	30	KF156338	Synechococcus phage S-MbCM7, complete genome	93212-93241	7	0.767
NZ_CP054010_1	1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10179-10208	30	NC_014534	Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence	202876-202905	7	0.767
NZ_CP054010_1	1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10179-10208	30	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	12009-12038	7	0.767
NZ_CP054010_1	1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10179-10208	30	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	142159-142188	7	0.767
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	NZ_CP013139	Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence	588579-588608	7	0.767
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	NZ_CP031836	Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence	98801-98830	7	0.767
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	NZ_CP020458	Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence	100697-100726	7	0.767
NZ_CP054010_1	1.21|11025|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11025-11054	30	MG592531	Vibrio phage 1.164.O._10N.261.51.A7, partial genome	27402-27431	7	0.767
NZ_CP054010_1	1.22|11102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11102-11131	30	NZ_CP045339	Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence	357374-357403	7	0.767
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	MN693078	Marine virus AFVG_25M36, complete genome	11482-11511	7	0.767
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	MN693355	Marine virus AFVG_25M40, complete genome	12239-12268	7	0.767
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	MT774408	CrAssphage cr130_1, complete genome	61439-61468	7	0.767
NZ_CP054010_1	1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9794-9823	30	NZ_CP046723	Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence	363136-363165	8	0.733
NZ_CP054010_1	1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9794-9823	30	NZ_CP016890	Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence	284345-284374	8	0.733
NZ_CP054010_1	1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9794-9823	30	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	334758-334787	8	0.733
NZ_CP054010_1	1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9794-9823	30	NZ_CP031650	Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence	158965-158994	8	0.733
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_LR134428	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 19	63798-63827	8	0.733
NZ_CP054010_1	1.9|10102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10102-10131	30	MN694063	Marine virus AFVG_250M885, complete genome	36462-36491	8	0.733
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	KT962247	Cellulophaga phage phi17:2_18, complete genome	136895-136924	8	0.733
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	KT962246	Cellulophaga phage phi4:1_18, complete genome	136417-136446	8	0.733
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	KT962245	Cellulophaga phage phi4:1_13, complete genome	136417-136446	8	0.733
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	KC821632	Cellulophaga phage phi4:1, complete genome	136417-136446	8	0.733
NZ_CP054010_1	1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10256-10285	30	NC_021798	Cellulophaga phage phi17:2, complete genome	136895-136924	8	0.733
NZ_CP054010_1	1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10410-10439	30	NZ_CP022416	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-1, complete sequence	113836-113865	8	0.733
NZ_CP054010_1	1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10410-10439	30	NZ_CP022418	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence	164903-164932	8	0.733
NZ_CP054010_1	1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10487-10516	30	MN013077	Klebsiella phage vB_KaeM_KaOmega, complete genome	137399-137428	8	0.733
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	AP014318	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C66, *** SEQUENCING IN PROGRESS ***	692-721	8	0.733
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	GU075905	Prochlorococcus phage P-HM2, complete genome	2084-2113	8	0.733
NZ_CP054010_1	1.16|10641|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10641-10670	30	NZ_CP030090	Lactobacillus reuteri strain YSJL-12 plasmid unnamed1, complete sequence	34479-34508	8	0.733
NZ_CP054010_1	1.20|10947|31|NZ_CP054010|CRISPRCasFinder,PILER-CR	10947-10977	31	MG592531	Vibrio phage 1.164.O._10N.261.51.A7, partial genome	27402-27432	8	0.742
NZ_CP054010_1	1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11256-11285	30	NC_009812	Listeria phage B025, complete genome	33992-34021	8	0.733
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	10232-10261	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP046008	Escherichia coli strain 1919D62 plasmid p1919D62-2, complete sequence	79620-79649	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP051133	Enterobacter hormaechei strain AMS-38 plasmid pAMS-38a, complete sequence	39412-39441	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	MF417868	Uncultured Caudovirales phage clone 7AX_1, partial genome	26330-26359	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP010244	Escherichia coli strain S56 plasmid B, complete sequence	9695-9724	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP042573	Enterobacter hormaechei strain E5 plasmid pE5_002, complete sequence	96719-96748	9	0.7
NZ_CP054010_1	1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	9871-9900	30	NZ_CP033252	Escherichia coli strain ECCHD184 plasmid pTB212, complete sequence	95078-95107	9	0.7
NZ_CP054010_1	1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10410-10439	30	NZ_CP021916	Sagittula sp. P11 plasmid unnamed3, complete sequence	84162-84191	9	0.7
NZ_CP054010_1	1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10410-10439	30	NZ_CP021915	Sagittula sp. P11 plasmid unnamed2, complete sequence	44266-44295	9	0.7
NZ_CP054010_1	1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	10564-10593	30	MN693705	Marine virus AFVG_250M220, complete genome	27559-27588	9	0.7
NZ_CP054010_1	1.18|10795|29|NZ_CP054010|CRISPRCasFinder,PILER-CR	10795-10823	29	MN694361	Marine virus AFVG_250M609, complete genome	30125-30153	9	0.69
NZ_CP054010_1	1.22|11102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11102-11131	30	KC206276	Escherichia phage EC1-UPM, complete genome	37290-37319	9	0.7
NZ_CP054010_1	1.23|11179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR	11179-11208	30	AP014358	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C94, *** SEQUENCING IN PROGRESS ***	8548-8577	9	0.7

1. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN693375 (Marine virus AFVG_25M113, complete genome) position: , mismatch: 4, identity: 0.867

tgataa-agagaaaataaacaatcaatataa	CRISPR spacer
-gataactgagaaaacaaacaatcaatatat	Protospacer
 *****  *******.************** 

2. spacer 1.2|9564|29|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_011246 (Borrelia recurrentis A1 plasmid pl124, complete sequence) position: , mismatch: 5, identity: 0.828

atagtattaattaaaattatagtcaaatg	CRISPR spacer
attttattaattaaaattataatctaata	Protospacer
**  *****************.** ***.

3. spacer 1.2|9564|29|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_011247 (Borrelia duttonii Ly plasmid pl165, complete sequence) position: , mismatch: 5, identity: 0.828

atagtattaattaaaattatagtcaaatg	CRISPR spacer
attttattaattaaaattataatctaata	Protospacer
**  *****************.** ***.

4. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP053834 (Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence) position: , mismatch: 6, identity: 0.8

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
ggataaagagaaaataaaaaataatgaaaa	Protospacer
 ***************** *** *  * **

5. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP010110 (Bacillus thuringiensis serovar indiana strain HD521 plasmid pBTHD521-4, complete sequence) position: , mismatch: 6, identity: 0.8

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
tcataaagagaaaatatataatcaaaaaat	Protospacer
* ************** *.****** * * 

6. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN698243 (Pelagibacter phage HTVC104P, complete genome) position: , mismatch: 6, identity: 0.8

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
ttaataagagaatataaacaaacaatatca	Protospacer
* *  ******* ******** ****** *

7. spacer 1.9|10102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to CP024688 (Bacillus wiedmannii bv. thuringiensis strain FCC41 plasmid pFCC41-4-144K, complete sequence) position: , mismatch: 6, identity: 0.8

catttgaagcaggagaatcaatattagcgg	CRISPR spacer
agtttgaagcaggaggatcagtattagcat	Protospacer
 .*************.****.*******. 

8. spacer 1.12|10333|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_023007 (Bacillus phage vB_BanS-Tsamsa, complete genome) position: , mismatch: 6, identity: 0.8

tttaagatgttacgcttatacttcaattta---	CRISPR spacer
attaagatgttactcttaaacttc---ttagtc	Protospacer
 ************ **** *****   ***   

9. spacer 1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to AP014234 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C93-MedDCM-OCT-S32-C16, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

ttgtttcgtaaagatggtcttcccactttt	CRISPR spacer
aattttcgtaaagatgttcttcctacttat	Protospacer
   ************* ******.**** *

10. spacer 1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to AP014235 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C93-MedDCM-OCT-S38-C9, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

ttgtttcgtaaagatggtcttcccactttt	CRISPR spacer
aattttcgtaaagatgttcttcctacttat	Protospacer
   ************* ******.**** *

11. spacer 1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MH579717 (Pelagibacter phage HTVC021P, complete genome) position: , mismatch: 6, identity: 0.8

ttgtttcgtaaagatggtcttcccactttt	CRISPR spacer
aattttcgtaaagatgttcttcctacttat	Protospacer
   ************* ******.**** *

12. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP046318 (Campylobacter coli strain FDAARGOS_735 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

tggatagtatgtatattctctttctcggca	CRISPR spacer
ttgatagtatggatattttctttctctacc	Protospacer
* ********* *****.******** .* 

13. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP011016 (Campylobacter coli strain FB1 plasmid pCC42, complete sequence) position: , mismatch: 6, identity: 0.8

tggatagtatgtatattctctttctcggca	CRISPR spacer
ttgatagtatggatattttctttctctacc	Protospacer
* ********* *****.******** .* 

14. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP040242 (Campylobacter coli strain S9 plasmid pCcS9_3, complete sequence) position: , mismatch: 6, identity: 0.8

tggatagtatgtatattctctttctcggca	CRISPR spacer
ttgatagtatggatattttctttctctacc	Protospacer
* ********* *****.******** .* 

15. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP028188 (Campylobacter coli strain CFSAN054106 plasmid pGMI16-001, complete sequence) position: , mismatch: 6, identity: 0.8

tggatagtatgtatattctctttctcggca	CRISPR spacer
ttgatagtatggatattttctttctctacc	Protospacer
* ********* *****.******** .* 

16. spacer 1.23|11179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MG065692 (UNVERIFIED: Campylobacter phage C13, complete genome) position: , mismatch: 6, identity: 0.8

tagggcaattaagaaagcaactcttaataa	CRISPR spacer
tgctacaattattaaagcaactcttaataa	Protospacer
*.  .******  *****************

17. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MH598807 (Pelagibacter phage HTVC120P, complete genome) position: , mismatch: 6, identity: 0.8

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tattcttaaatcaatagaagaaatgaaaaa	Protospacer
*  * ************* ********* .

18. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN693171 (Marine virus AFVG_25M555, complete genome) position: , mismatch: 6, identity: 0.8

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tttgtttaaagcaatagacgaaatgaaaaa	Protospacer
**   ***** ***************** .

19. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to AP013400 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G15, isolate: uvMED-CGR-U-MedDCM-OCT-S30-C37) position: , mismatch: 6, identity: 0.8

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tttatttaaagcaatagatgaaatgaaatc	Protospacer
**   ***** *******.********** 

20. spacer 1.3|9640|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KF156338 (Synechococcus phage S-MbCM7, complete genome) position: , mismatch: 7, identity: 0.767

aaacacagaagaatcacgaataccagcagg	CRISPR spacer
attaccagaagcatcacgaataacagcagt	Protospacer
*    ****** ********** ****** 

21. spacer 1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_014534 (Gloeothece verrucosa PCC 7822 plasmid Cy782202, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaatagcacaataatagactataaaacg	CRISPR spacer
aaaaatagcccaataatagagtagtagaaa	Protospacer
********* ********** **  *.* .

22. spacer 1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaatagcacaataatagactataaaacg	CRISPR spacer
acacctagcacagtaataaactataaaatt	Protospacer
* *  *******.*****.*********. 

23. spacer 1.10|10179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

aaaaatagcacaataatagactataaaacg	CRISPR spacer
acacctagcacagtaataaactataaaatt	Protospacer
* *  *******.*****.*********. 

24. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP013139 (Pseudoalteromonas sp. Bsw20308 plasmid pPBSW1, complete sequence) position: , mismatch: 7, identity: 0.767

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
ttgcttgctcagctgatttaatgctgcttt	Protospacer
****** ***************. ...** 

25. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP031836 (Lactobacillus amylolyticus strain L5 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.767

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
ttgcttcctcagctgaattgataaaaccgg	Protospacer
**************** **.***. *.. *

26. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP020458 (Lactobacillus amylolyticus strain L6 plasmid pL6-1, complete sequence) position: , mismatch: 7, identity: 0.767

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
ttgcttcctcagctgaattgataaaaccgg	Protospacer
**************** **.***. *.. *

27. spacer 1.21|11025|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MG592531 (Vibrio phage 1.164.O._10N.261.51.A7, partial genome) position: , mismatch: 7, identity: 0.767

taacttggttgaattgctcaacaggcaagt	CRISPR spacer
taacttggttgaaatgctcaaccacgaaaa	Protospacer
************* ******** .  **. 

28. spacer 1.22|11102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP045339 (Vibrio sp. THAF190c plasmid pTHAF190c_a, complete sequence) position: , mismatch: 7, identity: 0.767

gaaagtagctgaagcacggttagcagaagt	CRISPR spacer
caaagtagctgaagctcgtttagctaagct	Protospacer
 ************** ** ***** .*. *

29. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN693078 (Marine virus AFVG_25M36, complete genome) position: , mismatch: 7, identity: 0.767

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tttatttaaagcaatagatgaaatgaaaaa	Protospacer
**   ***** *******.********* .

30. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN693355 (Marine virus AFVG_25M40, complete genome) position: , mismatch: 7, identity: 0.767

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tttatttaaagcaatagatgaaatgaaaaa	Protospacer
**   ***** *******.********* .

31. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MT774408 (CrAssphage cr130_1, complete genome) position: , mismatch: 7, identity: 0.767

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
tattgagaaatcgatagacgaaatgaaaga	Protospacer
*  **  *****.*************** .

32. spacer 1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP046723 (Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence) position: , mismatch: 8, identity: 0.733

taagcgttattatccgctgcaacgcgagcc	CRISPR spacer
gatgcgtcattatctgctgcaacgcgctgg	Protospacer
 * ****.******.***********    

33. spacer 1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP016890 (Pantoea agglomerans strain C410P1 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taagcgttattatccgctgcaacgcgagcc	CRISPR spacer
gatgcgtcattatctgctgcaacgcgctgg	Protospacer
 * ****.******.***********    

34. spacer 1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 8, identity: 0.733

taagcgttattatccgctgcaacgcgagcc	CRISPR spacer
gatgcgtcattatctgctgcaacgcgctgg	Protospacer
 * ****.******.***********    

35. spacer 1.5|9794|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP031650 (Pantoea agglomerans strain TH81 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

taagcgttattatccgctgcaacgcgagcc	CRISPR spacer
gatgcgtcattatctgctgcaacgcgctgg	Protospacer
 * ****.******.***********    

36. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_LR134428 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 19) position: , mismatch: 8, identity: 0.733

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
ttttaaatagaaaataaccaatcaattgct	Protospacer
*  **** ********* ********    

37. spacer 1.9|10102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN694063 (Marine virus AFVG_250M885, complete genome) position: , mismatch: 8, identity: 0.733

catttgaagcaggagaatcaatattagcgg	CRISPR spacer
ggtttgtagcaggagaaacaatatttcctc	Protospacer
 .**** ********** *******  *  

38. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KT962247 (Cellulophaga phage phi17:2_18, complete genome) position: , mismatch: 8, identity: 0.733

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
cagattcctcagcagatttaatagcagaaa	Protospacer
. * ********* ************   .

39. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KT962246 (Cellulophaga phage phi4:1_18, complete genome) position: , mismatch: 8, identity: 0.733

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
cagattcctcagcagatttaatagcagaaa	Protospacer
. * ********* ************   .

40. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KT962245 (Cellulophaga phage phi4:1_13, complete genome) position: , mismatch: 8, identity: 0.733

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
cagattcctcagcagatttaatagcagaaa	Protospacer
. * ********* ************   .

41. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KC821632 (Cellulophaga phage phi4:1, complete genome) position: , mismatch: 8, identity: 0.733

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
cagattcctcagcagatttaatagcagaaa	Protospacer
. * ********* ************   .

42. spacer 1.11|10256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_021798 (Cellulophaga phage phi17:2, complete genome) position: , mismatch: 8, identity: 0.733

ttgcttcctcagctgatttaatagcatttg	CRISPR spacer
cagattcctcagcagatttaatagcagaaa	Protospacer
. * ********* ************   .

43. spacer 1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP022416 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-1, complete sequence) position: , mismatch: 8, identity: 0.733

aacagaacgcaggcagcaccacaacaagca	CRISPR spacer
gcccgaacgcaggcagcaccgcaacccgtc	Protospacer
. * ****************.****  *. 

44. spacer 1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP022418 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-3, complete sequence) position: , mismatch: 8, identity: 0.733

aacagaacgcaggcagcaccacaacaagca	CRISPR spacer
gcccgaacgcaggcagcaccgcaacccgtc	Protospacer
. * ****************.****  *. 

45. spacer 1.14|10487|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN013077 (Klebsiella phage vB_KaeM_KaOmega, complete genome) position: , mismatch: 8, identity: 0.733

ttgtttcgtaaagatggtcttcccactttt	CRISPR spacer
atgttccgtaaagatggtcttcacccaccg	Protospacer
 ****.**************** * * .. 

46. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to AP014318 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S32-C66, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.733

tggatagtatgtatattctctttctcggca	CRISPR spacer
cggataatatgtatatcctctttctttaag	Protospacer
.*****.*********.********. . .

47. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to GU075905 (Prochlorococcus phage P-HM2, complete genome) position: , mismatch: 8, identity: 0.733

tggatagtatgtatattctctttctcggca	CRISPR spacer
tggataggatgtatattatctttgatatga	Protospacer
******* ********* *****  ..  *

48. spacer 1.16|10641|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP030090 (Lactobacillus reuteri strain YSJL-12 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ttgcaatctctacaccgtacttcttttcat	CRISPR spacer
gataaatctcttcaccgtacttctctttgt	Protospacer
    ******* ************.**..*

49. spacer 1.20|10947|31|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MG592531 (Vibrio phage 1.164.O._10N.261.51.A7, partial genome) position: , mismatch: 8, identity: 0.742

taacttggttgaattgctcaacaggcaagta	CRISPR spacer
taacttggttgaaatgctcaaccacgaaaac	Protospacer
************* ******** .  **.  

50. spacer 1.24|11256|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 8, identity: 0.733

ttatgttaaatcaatagacgaaatgaaatg	CRISPR spacer
aggttcgaaatcaatagacgaaatgacata	Protospacer
  .* . ******************* **.

51. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catgggcgagaaattaatcaatcaatataa	Protospacer
..  .. ****** *** ************

52. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP046008 (Escherichia coli strain 1919D62 plasmid p1919D62-2, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catgggcgagaaattaatcaatcaatataa	Protospacer
..  .. ****** *** ************

53. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP051133 (Enterobacter hormaechei strain AMS-38 plasmid pAMS-38a, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catggtcgagaaaataatcaatcaaaataa	Protospacer
..  .  ********** ******* ****

54. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MF417868 (Uncultured Caudovirales phage clone 7AX_1, partial genome) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
aacagaagagaaaataaataatcaatgttt	Protospacer
 .  .*************.*******.*  

55. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP010244 (Escherichia coli strain S56 plasmid B, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catgggcgagaaattaatcaatcaatataa	Protospacer
..  .. ****** *** ************

56. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP042573 (Enterobacter hormaechei strain E5 plasmid pE5_002, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catggtcgagaaaataatcaatcaaaataa	Protospacer
..  .  ********** ******* ****

57. spacer 1.6|9871|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP033252 (Escherichia coli strain ECCHD184 plasmid pTB212, complete sequence) position: , mismatch: 9, identity: 0.7

tgataaagagaaaataaacaatcaatataa	CRISPR spacer
catgggcgagaaattaatcaatcaatataa	Protospacer
..  .. ****** *** ************

58. spacer 1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP021916 (Sagittula sp. P11 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.7

aacagaacgcaggcagcaccacaacaagca	CRISPR spacer
cgagcttcgcaggcagcacaacatcaagca	Protospacer
 . .   ************ *** ******

59. spacer 1.13|10410|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to NZ_CP021915 (Sagittula sp. P11 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

aacagaacgcaggcagcaccacaacaagca	CRISPR spacer
cgagcttcgcaggcagcacaacatcaagca	Protospacer
 . .   ************ *** ******

60. spacer 1.15|10564|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN693705 (Marine virus AFVG_250M220, complete genome) position: , mismatch: 9, identity: 0.7

tggatagtatgtatattctctttctcggca	CRISPR spacer
aggatagtatatatatcctctttcctttag	Protospacer
 *********.*****.*******..   .

61. spacer 1.18|10795|29|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to MN694361 (Marine virus AFVG_250M609, complete genome) position: , mismatch: 9, identity: 0.69

taccttgagatattcatagatacgtccac	CRISPR spacer
ctgtcagagatattcatggatacgtccgt	Protospacer
.  .. ***********.*********..

62. spacer 1.22|11102|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to KC206276 (Escherichia phage EC1-UPM, complete genome) position: , mismatch: 9, identity: 0.7

gaaagtagctgaagcacggttagcagaagt	CRISPR spacer
actgcgtgctgaaccacggttagcagaact	Protospacer
.  .   ****** ************** *

63. spacer 1.23|11179|30|NZ_CP054010|CRISPRCasFinder,PILER-CR matches to AP014358 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C94, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.7

tagggcaattaagaaagcaactcttaataa	CRISPR spacer
actcctaattaagatatcaactcttaatac	Protospacer
     .******** * ************ 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	132117 : 139733	6	Prochlorococcus_phage(33.33%)	NA	NA
DBSCAN-SWA_2	777633 : 840054	41	uncultured_virus(33.33%)	protease,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP054010|132117:139733|DBSCAN-SWA
CTTATAATGTATGTCCATCAAGATAATCTTGAAGAACTGACTTATAACTATCTGAGATTGGAAGGATAGCATCACCGATTACAACGCGGAAACGATCAATGCCATCAATCTTCTTCATGTGTACGATGTAGGAACGATGAATGCGCATGAATTCAGGTTTAGGAAGTGACTCCTCAATCTTCTTCATGTTCATTAGACTCATGATTGGCTTATGGTCGTTAGCAAGATAAATCTTAACATAGTCCTTCAATCCTTCAATATAGAGGATGTCATCAAACATGATTTTAACCAGTTTGTACTCACTCTTCACAAAGATAAAGCGGTCGTTCGATGCATTCTCTGTCTGACGGGTACTTTGGAACCAGTCTAAAGCCCTGTTTGCACCTGCTAAGAAGTCATCATAGCTAATTGGCTTCATAAGATAATCAATTGCATTTGCCTTGTAACCATCTATAGCATATTGGCTGAATGCAGTTGTGAAAATAATCTTAGTTTCCTTTGGTAGAATCTTTGCAAACTCCAGTCCACTAAGTTCAGGCATCTGTATATCTAAGAATATGAGGTCAACCCTATTCTCACGGATGGCTTTTACGCCTTCTACAGCACTATTAAAAACACCAATTAAGTTCAAAAAGAGTGTTTTCTTAGCATAACTCGCAAGCAAGTCTGCTGCTAAAGGTTCGTCGTCAATGATTATACAGTTTAGTGTCATAAATGATAATTTTAGATGAATATGTATTTCTATTACGATCAAATCCCTTCTCCCATTTGTACTTACCAGGGTAAGCAAGCTCAAGACGGCGCTCTACTTGTTTGAGACCTATGCCGTGACCGTTCCTTTCTGCCTCTCCCTTTGGGTTGTTACTATTTTGTATGGAGAATATTATTTGCTCATTATTTGCATCTAACTTTATGTGAATAAAGTTCTTTTGCTCTGGATTAATACCATGTTTAAAGGCATTCTCTAACAATGAGATAAATATCATTGGCGCAACATGGATGTTACAATTAGATGGGATGTTACACTCGCGTTTGATTTCTACATTCTCTGGTATGCGTATCATCATCAAGTCGACATAATTGTGTAAGAACTCTACTTCTTCCTTCAGGCAGACGTAAGGCTGCTGGTTGTCATAGAGAATATGTCGTAACATCTTTGAAAGGTCGATAATTGCCTTCTGCGCCTTTTCTGTATCGAAAGCTGTCAGCGCGTAGATATTATTCATTGTGTTGAGCAAAAAGTGTGGGTTGACTTGCTGACGTAAGTTTACCAACTCAGCCTTTGTCATTGCTGTTTCTGCCTCACGCTTTTCCTTTTCAGCCTTTGACCAACGCTGTGCCATTAGTATCGATGTTGCAACACCAGCACAGATACTTAGGTTAAAGACATTGCGTATAATAAAAAAGATGTGTGGGTATACGTACTTGTCCTCTTTGTTTTCTACAAAGATTTGGTATGGATAAGTCGTCAGGTTTTGCTCACCTGAGATGTAGTATAACCATTCGTGCTGTGCAATAGATAAGAAAAGGATGAGCAGTGTATTGATTACCCAAAACTCTTTCTTCCGTCCCTTTAATAACATGGGGGCAAGTACAAAATAATTGGTATATGCAACTGCCATCATTGAAAGGGGAATGATATATATCGACAAGTCGTTTTGCCATGATGTATGTCCTTGCGGAGCGTACAAAATTGGTATGAGGAAAAGCGGAAGCCAAATGATAATTTGGTTCCAAAAGCTCTTAAATATGTCTGTTTGTTTCCTCATTTATTACTTTTATTTGTCTTTACAACTATATCTGCAAACAAAGGTAATAAAACTTTTTGTAAAATAAAATGTATTGACTGAATATGTGAGTTTTTTTTACATTAACCTATTGTTATATATATACAAAAGGTTTTTAATTAACTTATTTTTATAATAAAACAACCCTAAACAACACTAAAATAGCTTTCTTTACTCTATTTCCTACGTTGTTTAGGGTTGTTAGATGCTGTGATAATAAATATTTACAATATCTATTTTGTAAAGCTGTTTAAGCGTGCTATATATTTGCCAAGAATGTCAAACTCGAGGTTTACCACAGTGCCAATATTAATGTCAGCAAAATTGGTATTCTCTCGTGTGTAAGGAATGATGGCTACCTTAAAGCTGTTATCTGTAGGTTCGCAAACAGTCAGCGAGACGCCATTGACCGTAACTGACCCTTTATCAACAGTGAAATAGCCACGTTGTGCCATCTCTCGGTTGCACGGATATTCGAAGGTGAAATAGGTACTACCATCTGCATCTTCCATATTAACACACTTAGCTGTTTGATCAACGTGACCTTGTACGATGTGTCCATCTAATCTACCGTTCATAATCATTGAACGTTCTATATTCACACGATCCCCCACTTTGAGTAAGCCTAAGTTCGAGCGTTCAAGGGTTTCCTTCATGGCTGTCACCGTATAGGTATCGTCTTGGAAGCGAACGACCGTAAGGCACACTCCATTGTGTGCAATACTTTGGTCAATCTTCAATTCCTTTGTAAATGAACATTGAAAAGTGAAATGGATATTCTCCTGTTCATGTTCAATCCCTCTAAGGATTGCCATCTCTTCTACAATTCCTGAGAACATTGCTAAATTTCTTTTATTATCCCCTTTAAGAAAGCCTAAATGATGGTATAAGTATTGATAGATAATCTTTTATAACTTCACAGGCTACTTATAGGAGGTTAAGTTTTACATAATTACTATACGCTTGAATAATTGAAAAAGGTGGGGAATCACTTGGAAACCCCACCTCAATCCCTCTTCTTTAAAGAAATGGGAATTAGAAAAGTCGTATCGACGATGTGATGAAAAGTCCGAGTATCAATGATAAGAGAGCTCCTCGTCTTTGTAATCCACTGACCTTGCGGCTTAGTCGCTGAAATGCGATTTATGTGGCCCGCCATTAACAAAAGAAGTCATCTCGGGTTTTCTAATTTATTTGATGACTATCCCGATCGAATCGATACGACTAAATCTGTATCCTTTCTGCGTGCAAAGTTAGCATAAAGATTTTTATCCTCCAAACATTTTATACTTAAAAGTATTTACTTCTGGAGGTGAATCCCTTTGTTCTTTGTGTTGAAAGGAGCAGAAATGATAATGTTCTTTTGTGTATAACTTTAATAGTTTATTGGTTTTATAACCTTCTTTTGATAACAATTTGCCCTCGTCATGAGTACATATTTGCAGGTGTTTATCGCTCCACACCATTGGTGCTAAGCATCAACACGACATGTGCTAAGCCTCCGCACCACACGTGCTAAGTATCGGCACGTTGATTAAATGTGAGAAGAAAGGTTCATTATTGTCATTTTAGAGAATGAAACCAATATTCTTGTCTTTTTATAGGAGTGCATCTTGTAGAATTTCACTTAACGTAGGATGGATATGAATGATGTCTCGTATCTTATCCAGTTTAGCATCATAATTCATTAAAGCTGCAACTTCTTGAATAAGGTCGGCAGAGTGTGCGCCATAGCTGTGTGCGCCCAATATAGAGCCATCTTCAGCTATCAGCACCTTTATCATACCTTCAGTTTCTTCCATGCTTAAAGCCTTACCATTGGCGCGATAGAAGCCTTTTCGAGTAGAAAACTTTATTTCCTCAGCTTTACACTGGTCTTCAGTCTTACCCACGCAGGCTGCTTCTGGATATGTAAAGATTGCAGATGGCATGATATCAAGGCGGATATTATCGTCCTTTCCAAGAATATGATTGACAGCACGGAAGCCTTGGAAGGTTGCTGCATGCGCTAACATTTGGCGTGCATTGACGTCACCGATAGCATATACACCCTTCACATTTGTTTCCATATTGTCATTGACAACAATACCCTTTGCGTTTACTTCTATGCCAGTTGTTTCAATACCAATATTGTCGAAGTTAGCTTGACGACCGGTAGCAATCAATACAAGGTCGGTATCAATTCTATCTTCTTTACCCTTTTTATCGAATACAACGGTTGTATACTCTTGTCCACTCTCTGCAGGTGATAGGATTTGTTTTACGGCACTCTGCATGTAGAAGGTTACACCTCTTTTCTCTAATGTCTTCCTTAAGCGTTTAGCTATGTCGCTGTCAATAGGAGGGAGGCATTCCTTCATAAATTCAATAACTGTCACTTCACTACCGAAAGCTGAGAAAGCCGAGGCAAATTCCATTCCGATAACTCCTGCTCCAATGATTGTGAGACGGTTAGGAACTTTCGCAATAGAAAGTAATTCTGTGGATGTGACAATGTTTTGTGCTGTTTCAGACTGGCTCAAGAAGTCTTCTTCACTCATGAAAGGTGGCATCTTTGAACGTGATCCAGTCGCAATGATGATATGCTCAGCCTCTATTTGTTCGCCATTTACTTCAATAACATGGTCAGAAACAAATCGAGCCTCGCCTACAATAAAGTCTATACCAGGCTGACTAAGCAAAGTGCTTACGCCCTCTCTAAGTTGATTGATAACTCCTTCTTTCCTCTCCATTACCTTTGTAAAATCGAGCGGGGGAGTCGTTTCGTAAAGAGAAGAAGTCGTAAGGCGTAGCTCAGCATCATGTGCAAGGCATTTCGTAGGAATACAACCAGCATTCAGACAGGTTCCACCAGGCTGTGCTTTCTCAATGATAGTCACTTCCAAACCATTCTGAGCAGCATAGGAAGCGGTTCGGTAACCACCAGGTCCCGAACCGATTATTAATAGATTTGTCTTTTTCATATTCAATCTCTAATAGAGTTACTGTGGAGATATGCTATACATTCTCCTCTACGTCGTTGACAAGCTGACGATAAGTAAGGATTGGATGCTTAGCTGCAAGAACATCATCTACACGTCCAATAGGTGTGTTGTATGGTGCTCCCTTAACAAGCTCTGGGTTCTCAAGAGCCTCTTTAGCAATAGTATGCATCACCTCTATAAATCCATCAATAGTGTCCTTACTTTCAGTTTCAGTAGGCTCAATCATCATAGCCTCATGGAACAGAAGTGGGAAATATATTGTTGGAGCATGATAGCCATAATCGAGTAGGCGTTTGGCAACATCCATTGTTGTTACACCGGTACTCTTATCCTTCAAACCATCGAATACAAACTCGTGTTTACAAAGTGTGTCAATAGGAAGTTCGTAATCATCCTTTAAACATTCCTTGATATAGTTCGCATTTAGAGTTGCAAATGGTCCAACCTCCTTGAGATGCTTCTTGCCAAGTGTGAGAATATAAGTATAGGCACGAAGGATAACGAGGAAATTGCCGAGGTAACCGCTAATACGAATATTATCAGACGAGAACTCTCCTGTCGTATCTGGATTGTCAACAACAAAACCATCCTTTGTTTTCTTTACATGTGGCTTTGGAAGGAATGGAATTAGTTTCTCGGCGACACCGACAGGACCAGCACCAGGACCACCTCCACCATGTGGTGTAGAGAATGTCTTGTGTAGATTGAGGTGAATAACATCGAATCCCATGTCTCCAGGACGTGCTGCACCTAATAGTGGATTGAGGTTGGCACCATCATAATACAGCAGACCGCCACAGTCATGTATGAGCTTAGCAATCTCTGGAATATCTTTCTCAAAGAGACCTAAGGTGTTAGGATTGGTCATCATCATACCCGCAATGTCATCACCCAAGAGAGGTTTTAAGTCGTTGACATCAACAAGTCCTTCAGCTGTACTCTTTACTTCCACAATCTCTAAACCACAAACAGCAGCAGAGGCAGGGTTAGTACCATGAGCAGAGTCAGGTACGATAACTTTTGTTCGCTTTGTGTCACCACGCTGTTGATGGTAAGATGCTATGAGCATCAGACCTGTTAACTCGCCATGCGCACCAGCGTATGGGTTAAGTGTGACTTCTGCCATACCCGTAATAGAAGCAAGAGCACGTTGAATATTGTATTCAACCTCCAGTGCACCTTGGACTGTTTCAATAGGTTGGTGGGGGTGAAGGGCTGTAAAGCATGGCATTGAAGCTATCTCTTCGTTGATGACAGGATTGTACTTCATCGTACAAGACCCCAGAGGATAGAAACCATTATCAACGCCAAAGTTATTCTCACTATGATTAGTATAATGACGTACAACCGTCATCTCATCACATTCTGGTAGCTCTGCATCTTTCTCTCGTTTGCAGAAGTCGGGTAAAGGATGATGGCCAAAACGATTCTCAGGGAGGCTGTAAGCACGTCTTCCTGGATGTGACAACTCAAATATCAGATTGCCATATAGTTTATTATTCATTGTTGCGTAGATTTAGAAAAACTTTGTGTGACTATAATAATCCGACGAGTGTATCAATCTCCTCTTTTGTACGTTTCTCTGTAACGGCAATAAGGAGTTTGTCATCATCAACCTTGATACCTGGGAGAATGCCCTGTTTGATAGCCTTGTCGAAGAAGGTGTCGCGTTCCTTCATTTGAATAAGGAACTCATTAAAGAAAGGCTTGTTGTAAACAAGCTTAACTTTTCCTGTACTAAGGAGTTGTTCGCAAAGGTAATGTGCACCATCATAGCCTATCTGTGCTGCTTCCTTTATACCCTCTTTTCCCATCATACTCATGTAGATTGTAGCATAAAGCGCCATCAAACTCTGGTTAGAACAGATGTTTGAAGTTGCTTTCTGACGACGGATATGCTGTTCACGTGCTTGTAGCGTCAGTGCGAATACACGCTGTCCACGGCTATCGCATGTCTTACCCACGATACGACCAGGGAGCTTACGCATTAGCTTTTCAGTTGAACACATGTAGCCTGCGTATGGTCCACCAAATGCCATTGGAAGTCCAAGACTCTGAATATCGCCTATAGCAATGTCTGCACCCCATTCTCCTGGTGTCTTTAATAAAGCAAGGTCAGCTGCAACACTGTTAATAATGAACAGTGCCTTTTCTTCATGGCAAGTATCAGCAAAGCCTGTAAAGTCTTCAATAATACCATGTCGATTAGGCTGTTGTACGATAACTCCAGCCACACCACCTGCCTGCAATTGGTTCTTTAAGTCTTCGTGTGAAGTCTCTCCATCAACCGCCTTGATTGCCTTGAGCTTAATGCCATGAAAATGTGCGTAAGTCTTTAATACGCCAATGATATTCTTGCATAAAGTCTCAGAATATAATACAGTGTCAGCCTTCTTGGCATTATCAAAAGCTACCATCATAGCTTCAGCACTTGCTGTAGTGCCTTCATACATAGAAGCGTTGGCAATATCCATACCAGTAAGTTCAGCCATCATACTTTGGAACTCAAAGATATAATGGAGTGTTCCTTGTGATATTTCAGCTTGATAGGGGGTATATGATGTAAGAAACTCCGAACGACTGAGAAGATTCTGAATAACACTTGGCGCATAGTGGTCATATACACCTCCACCTGCGAAGCAAGTAAGTTTGTCATTCTTTTGTCCAAGTTTCTCAAAGAAAGCGCGTATTTCTAACTCGCTCATCGTCTCAGGAATATCATAATCTCCCTTGAAACGGATGCTCTCGGGTACTTCAGCATATAGGTCTTCAAGCTTCTTTATGCCAATACGGTCAAGCATCTGTTGTATATCCTCACCTGTGTGAGGTAAAAACTTATGAATCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP054010|132117:139733|132117_132828_-|WP_004359872.1|DBSCAN-SWA
MTLNCIIIDDEPLAADLLASYAKKTLFLNLIGVFNSAVEGVKAIRENRVDLIFLDIQMPELSGLEFAKILPKETKIIFTTAFSQYAIDGYKANAIDYLMKPISYDDFLAGANRALDWFQSTRQTENASNDRFIFVKSEYKLVKIMFDDILYIEGLKDYVKIYLANDHKPIMSLMNMKKIEESLPKPEFMRIHRSYIVHMKKIDGIDRFRVVIGDAILPISDSYKSVLQDYLDGHTL
>NZ_CP054010|132117:139733|134136_134742_-|WP_004359870.1|DBSCAN-SWA
MFSGIVEEMAILRGIEHEQENIHFTFQCSFTKELKIDQSIAHNGVCLTVVRFQDDTYTVTAMKETLERSNLGLLKVGDRVNIERSMIMNGRLDGHIVQGHVDQTAKCVNMEDADGSTYFTFEYPCNREMAQRGYFTVDKGSVTVNGVSLTVCEPTDNSFKVAIIPYTRENTNFADINIGTVVNLEFDILGKYIARLNSFTK
>NZ_CP054010|132117:139733|135501_136866_-|WP_004359869.1|DBSCAN-SWA
MKKTNLLIIGSGPGGYRTASYAAQNGLEVTIIEKAQPGGTCLNAGCIPTKCLAHDAELRLTTSSLYETTPPLDFTKVMERKEGVINQLREGVSTLLSQPGIDFIVGEARFVSDHVIEVNGEQIEAEHIIIATGSRSKMPPFMSEEDFLSQSETAQNIVTSTELLSIAKVPNRLTIIGAGVIGMEFASAFSAFGSEVTVIEFMKECLPPIDSDIAKRLRKTLEKRGVTFYMQSAVKQILSPAESGQEYTTVVFDKKGKEDRIDTDLVLIATGRQANFDNIGIETTGIEVNAKGIVVNDNMETNVKGVYAIGDVNARQMLAHAATFQGFRAVNHILGKDDNIRLDIMPSAIFTYPEAACVGKTEDQCKAEEIKFSTRKGFYRANGKALSMEETEGMIKVLIAEDGSILGAHSYGAHSADLIQEVAALMNYDAKLDKIRDIIHIHPTLSEILQDALL
>NZ_CP054010|132117:139733|138422_139733_-|WP_004359867.1|DBSCAN-SWA
MIHKFLPHTGEDIQQMLDRIGIKKLEDLYAEVPESIRFKGDYDIPETMSELEIRAFFEKLGQKNDKLTCFAGGGVYDHYAPSVIQNLLSRSEFLTSYTPYQAEISQGTLHYIFEFQSMMAELTGMDIANASMYEGTTASAEAMMVAFDNAKKADTVLYSETLCKNIIGVLKTYAHFHGIKLKAIKAVDGETSHEDLKNQLQAGGVAGVIVQQPNRHGIIEDFTGFADTCHEEKALFIINSVAADLALLKTPGEWGADIAIGDIQSLGLPMAFGGPYAGYMCSTEKLMRKLPGRIVGKTCDSRGQRVFALTLQAREQHIRRQKATSNICSNQSLMALYATIYMSMMGKEGIKEAAQIGYDGAHYLCEQLLSTGKVKLVYNKPFFNEFLIQMKERDTFFDKAIKQGILPGIKVDDDKLLIAVTEKRTKEEIDTLVGLL
>NZ_CP054010|132117:139733|136900_138391_-|WP_004359868.1|DBSCAN-SWA
MNNKLYGNLIFELSHPGRRAYSLPENRFGHHPLPDFCKREKDAELPECDEMTVVRHYTNHSENNFGVDNGFYPLGSCTMKYNPVINEEIASMPCFTALHPHQPIETVQGALEVEYNIQRALASITGMAEVTLNPYAGAHGELTGLMLIASYHQQRGDTKRTKVIVPDSAHGTNPASAAVCGLEIVEVKSTAEGLVDVNDLKPLLGDDIAGMMMTNPNTLGLFEKDIPEIAKLIHDCGGLLYYDGANLNPLLGAARPGDMGFDVIHLNLHKTFSTPHGGGGPGAGPVGVAEKLIPFLPKPHVKKTKDGFVVDNPDTTGEFSSDNIRISGYLGNFLVILRAYTYILTLGKKHLKEVGPFATLNANYIKECLKDDYELPIDTLCKHEFVFDGLKDKSTGVTTMDVAKRLLDYGYHAPTIYFPLLFHEAMMIEPTETESKDTIDGFIEVMHTIAKEALENPELVKGAPYNTPIGRVDDVLAAKHPILTYRQLVNDVEENV
>NZ_CP054010|132117:139733|132802_133885_-|WP_036886101.1|DBSCAN-SWA
MRKQTDIFKSFWNQIIIWLPLFLIPILYAPQGHTSWQNDLSIYIIPLSMMAVAYTNYFVLAPMLLKGRKKEFWVINTLLILFLSIAQHEWLYYISGEQNLTTYPYQIFVENKEDKYVYPHIFFIIRNVFNLSICAGVATSILMAQRWSKAEKEKREAETAMTKAELVNLRQQVNPHFLLNTMNNIYALTAFDTEKAQKAIIDLSKMLRHILYDNQQPYVCLKEEVEFLHNYVDLMMIRIPENVEIKRECNIPSNCNIHVAPMIFISLLENAFKHGINPEQKNFIHIKLDANNEQIIFSIQNSNNPKGEAERNGHGIGLKQVERRLELAYPGKYKWEKGFDRNRNTYSSKIIIYDTKLYNH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004359872.1|132117_132828_-	response regulator transcription factor	A0A2R2ZGH8	Clostridioides_phage	7.2e-19	30.3
WP_036886101.1|132802_133885_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	8.7e-08	25.2
WP_004359870.1|134136_134742_-	riboflavin synthase	A0A2I2L4R9	Orpheovirus	1.6e-22	35.9
WP_004359869.1|135501_136866_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.7e-53	33.5
WP_004359868.1|136900_138391_-	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	M4QFZ1	Prochlorococcus_phage	7.4e-82	39.5
WP_004359867.1|138422_139733_-	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	E3ST28	Prochlorococcus_phage	2.0e-59	37.3

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP054010|777633:840054|DBSCAN-SWA
TATGCTGATAACCAACTTGATTAGCCGATATATGAAGCTCTGCAAAGCAGCATTTAGTGCTGAAGATGGAGCAAAGTTAAACAAAAGTATTCAAACAAACGTCATGGAAATGCTTTTTCTTTTGATGGTCATCCCAAGGAAATGTAATTTTACGCAGATGGGACGCTATGGAAAGCGTGGCGAACAATGCTATCGGCAGACGGCAGAGCGCAGCGTGAACTGGCTCGAAATAAATATGTGGCTGAGTGCTTTCGCCTTCAAGCAGGGTAAAGGGCTCAATGCCATCGTTATTGATCCAAGCTTCATCAAGAAGGCTGGGAAGCATACCCCATACGTGGGTACGTTTTGGTCGGGCTGTGCAGGTGCGGTAAAGCACGGTCTTGAGATCCTCGGCATCGGTGTGATAGACGTGGACTTGCATGAGTGTATGATGCTCAAGGCTGTGCAGACCACATTGGAAAAAGGGGAGGAGAAAAAAGAGATGAGTCTATACGACTGGTATACCAAGGTGTTGGAGGACGACAAGGTAACCTTACAGCGTATTTGCAAGGTTCTTGTCGCTGACTCAGCCTTCTCCAAAAGACCTTTCATCGACAAGGTAATGAAGATGGGCTTCCATGTTGTGAGCCGCTTGCGTCATGACGCAGCCTTGTTCTACACATGGGATGGGGAACCCACGGGAAAGCCCGGCCGTCCTCGTATCAAAGGTGACAAGATTGACGTAAGGAACATCGACATATCCAAAGGCAATGAGCTTGATTTAGGAGAGACCAAAGGCAAAGCCTATGCGCTCAAGGCGTGGTGCAAGTCCTTGCATAGGGTCGTGTCGATTGTCATCCACGAGTTGCCCAACGGTGTCCGCCGTTTGTACTTCTCTACGGATGAGAGCATGAGTGGACGCGATGTGATGGAGTACTATACCACACGTTTCCAAGAGGAGTTTTGCTTTCGCGACGCAAAGCAATTCCTCGGTCTTACCGATTGTCAGGCACGCGACAAGAGAAAACTTGAATTTGCTTTCAACTCTTCATTCACAGCACTCAATGTGACCAAAATCATGTGCAAGGAACTTGGCACGTCCATCGGTCGACTTAAAGCGCAGATGGTCAATGCCTACTATGCACAACGAATTATTGACGTGTTCGAGAAGAACCCGAACACGCCATTAAATAAAGAAAGGATAAATGATATATTTAGTTTCGCTGCTGATGCAGCATAATATTTAACGGACTATTGGTTATGCACACCACCTACAACAGATGTAAGGTATAATTCGAAGTCCTGAACAACGGCACTTGTCAGTTCTGTCAGTCCAATATCCTTGCGATGATACTTTGCTTGTAGGAAATCCTGAAAGTTCTGCCTCACCACCTTATACTTATAAAAAGTACACTTAGTTAATGTCTTGCCAACTTGTTGTGTGATGGAGTCTATGTACTTGTCAAAGACTGGCAGAAAAGTTGTATATTCTTTGTCTGTACCAAGGAATACCGACCTGATAAGGTCTATGGAAAGTTCCTCTGAAGTTTCATATTTCCAGTAAATCTGCATCAGCGTTGTTGTCAGTGCATCTATAGAAGCATTAATGAAGAGTGCTTCTGCTGTTCTGCCAATCATTCTGCTGGTTTTGTTACTCCACTTGGATTTATCCACAAAAATTTTAGTGGATCCAAGATTTGCCTTTTCGCCACCGAGATATATTCGGAGCATTACAGGTGATTTTCCTTCTTTGTTCTCATAGTTGGAACGTAGGTAGTAGGATACCTTGAAAGTCGTTTTCATAACGCATCATTTTAGTGTAGCTTTTTGGCTACAAAGTTCGACATAAGTTCTTGAAAAAGAAAGTTTTGCATGCCGTCAATTTAATAGTCATTTTCCATTCATTGCTACATTTTTTTGAGAGTCTGCTTTTGTGTAGCAATTTCTGTAGCAGAAAATGACCGAATGATGACTATCAAAAGGTATAGTTTGGCAGTCAAACGGATATGGATAAAAAACAAAAATCGCTGTAAAACCTTGATTTTACAGCGATTATTCTTGTTTTGAAGGCTAAAATGACGTGTTGTTTGATGTCCTTTTGAACCCCCTTTGTGGACCAGCCTGGGCTTGAACCAGGGACCTCCAGATTATGAGTCTGTTGCTCTAACCAACTGAGCTACAAGTCCTGAATTTTACAAACTCGGGTGCAAAGATAATGAAAAAAAATGGGAAAAGAGAAAGGATAGTAAGGAAATTTAATGTTTTAACACATTTTGAATGCCTGAGCGTGGGTTTATGGCTGATTTGGAGTACCTTTGCAGAGAATAAAGGATTTTTAAGACAGTTAGATTGAATACTATATATATTAAGCGAGGCGAGGAGTATGAACTTGTAGAGCAAGTTGCAACCATAGGGTTCTTTGATGGTGTGCATCGTGGACATCAGTTCCTGATTAGTCGTGTCATTGACGAGGCTAAACGGTCAGGAATGGCGTCGGCAGTCATCACCTTCGACCGACATCCGCGTCAGGTACTGCAGGCTGACTACCAACCAGAACTGCTGTCAACACTCGATGAGAAGCTACTTCTGCTCTCAAAGACACATATTGACAATAGTTTCGTACTGCATTTCGATACTTCGTTGGCTGCGCTCTCAGCTCATGACTTCATGCAAGAGGTGTTATGCAAACAGCTGAACGTAAAGAAGCTCATCATAGGTTACGACAACCGCTTCGGACATAACCGCTCTGAGACTTTTGAAGACTATGTCCAGTATGGCAAGGAAATGGGTATTGAGGTCATTCGTGCCGATGCCTTCCTGCCAAATGATGAGAAAGTGAGTTCTTCTATCATCAGAAACGACCTTCGCACGGGCAATATTGAGGCTGCCAACCGCCTTTTAGGCTATCCTTATACGATAGAGAGTCGCATCGTGAGTGGCTATCAGAATGGGCGCAAGATGGGTTTCCCTACAGCCAATCTCGATGTGAATGGTTGCCAACAGCTGCTCCCTGCAAGTGGTGTCTATGCGGTCATGGTGCGCTTGAAAGATTCTGTTGGATGGAAGCGAGGGATGATGAACATTGGGCATCGGCCTACTTTCAATGGCACAACCACCTCGATAGAGGTCAATCTCTTTAATTTCACAGGAAATCTCTATGGACAGGAACTCCTTGTAAGTTTCATTAGTAAGATCAGAGACGAGCATAAGTTTGACTCTTTAGAAGCCTTGGCACAACAGCTGAAGCAAGACAAAGAGCAAATCAATCGCTTGTTTGATGAGACTTATCACATACAAGAGAATATTATTAATACACCCTAAGATTCGCAGAAATGAACAATAAAAACGTTTTGAGCGCAACGCTCTATGTCATCTTATTTGTTTCACTTTTCATCTTGATACAAAGTCTTTCTTTCAAGGGAGGTAAGCAACTTGTAAGCCTACTTGGAGGGACAGAGGCTGCTGATGGGGATTATCTGACTAAAAATGGTGAGACTCTTGCCATAACGGCAGTCATCAGTAGTCTTGCAACTTTAATTCTTTTCATCGCTACAAAGTGGGCACCTGTATCTGGTAACTATTTGAAGACGCGTCCTTGGGCTGTCCTCATGTGGTCGGCTCTCATAGCTTTAGGTTCGATACTCCCGCTGCAATTCCTTGCCGAGAAGATTAATCTAACGATGCCAGCGGGCACAGAAGAGATGTTTGAAAGTATCATGAAGGTGTCTTGGGGCTATGTAGCCTTAGGAATGATGGTGCCTATTGCTGAGGAGATCGTCTTCCGTGGCGCTATTCTACGCGTACTACAAAACGCATTAGGCGAACGCAAACGATGGATAGCCATTGTCATTTCAGCCCTCATCTTTGGTATTGTCCATTTTAATTTAGCACAGGGCTTACACGCTTTCTTGATTGGTCTGCTATTGGGTTGGCTCTATTCGAAAACGGGTAGTATTCTGCCAGGCTTCGTATTTCATTGGGTGAACAATACGGTGGCTTATCTTATGTTCAACCTCATGCCACAGATGAACGATGGCAAACTCATCGACTTCTTCCACGGCAACGACCGCATGATGTACGGAGGTCTGTTCTTCTCGCTCTGTATCTTTGTTCCTTCGTTGCTGCAGTTAATAGGAAGGATGCCAAAGGGGAATAAATAAGCAGTTTTCCTATAAAGACATCTAATAGAATAAGCGCATAGGAAAAGAGACGATAATGCCTATCCTCTCACATTCCTACCCTCTTTAAGAAACGTTCTAAGGCTTAACACCAGATGTGCGAACGCTTAGCACCAAATGTGCGGAGCCTCCGCACCACTCAATGATACTATTCCTTTATTATATAAACGATAGAGATTAAACAAGAATCGACCATCACATAGGCTGTTGAGAGCCATGTAATGGTCGATTACTTACTTATAGACTTTACTGTTAGCGATTACATATTCTCGCACTCCTCGTTCTCATGAACAGGGATTTTAGCCTCCTTTGTAGTCTTTTCTGCCTTATAACCGAACTTTTCAAAAGCCTTTTGAAGCTTCTCCTCATTGGTCTTCTGAGCATCGTAGGTTACATAAACTTTCTGCTCTTCAACACTTGTCTTAATCTCCTTCACACCCTTTGCAAAGCGGAGGTTGTTCTTTACTTTCGCCTCACAGTTAGCGCAGTGCATCTGTGGAGTAGTTGTGAAGATAACTGTCTTAATGTCTTTGGCTGTTGCAATCATGGCTACCATGAGCATCAGCATTGTGAAAATAGCTTTTTTCATAATTGTTCTTTGTTTGAGGGAGACGTCCGAAAGCGTGTTTCAAGACGTCTCTCTGTGTTGTCGTTTATGTTATTCTATTGTGAAAAATGTATGTTTACTGTCGTTTACCGAGGTTCAGACGGATACCAACGTATGCCATTGCACCCTCGACAGGACCATAGACCATTGTTGGTTCGAAGCTGTTAGCCCACGGATTTTGATAACCAATGATAGGGTTCTTCTGCTTATAATTGGTAAGGTTTTCCCCACCTATGTAAAGCGAGAAGTGGCGGAAGTAGCGTGTCACCTGACCGCTAAGCTGTCCGTAGGCCTTATAGCTGCCTGCCCATGAGCGTTCGCCCGATGCTAAGGTGTAAGATTCTGGCATTCTACCACCTCCGTTCAAGGCTGCAGTAGCATCAAACTGCCAGACTCCTAAAGGTGTTTTATAGCTGAGCGTTAAGAGTCCTTTGTAACGACTCTGCAGTGGTTTCCACATCAGTTTTCCTCCATACGTCGACTTAACGAGGTTATATCGGTAGGCTGCTCCCAGCTCAAGACCCTTGAACAAAGGATAAGAAGCTTCGATTTGGAAGGTATGCGAGAAGCTCTTTCCATTGAGATTTGTGATATGCAGCTCCTGTGGATTACTGTCATAGTCTATCAACATCTGTGAAAGGAAGTGCGTATAATAGTAATCAGTATTGATTTTCAGCATCTTACTTCCTATTGGAATCAGGAAATTAAGACTCGCACCATAGTTCCATGCAGCCTCTTGATCGAGCTTATCGATGATGAGTCGGCGGCCCGAAGCCATGAGGTAGTTGTTCTCAGCCAATGCGTGTGGACTGCGATAGCCCTTACCTGCAGAGAGGCGGAGGGTCAGGAAGTCGGCTGGCACCCATTTCAAGTGGAAGCGAGGAGTGAAGAACGTACCGTAAACATTGCTATGGTCGACGCGCAATCCTGCCATAGCGATGAAGCGACTGTGCAGATTATAGGTGTACTGAACGTATGCGCCCGGTGTTGTCTCACTCTCAATACCACGCGTGAGCGGGAAGATATTACCGTAATCAGAAGGCACAGCCGTTGCAGGTAGGGTCAGAGTCTGATGCAAATAATCATGGTTGAGACTCAAACCAGCAGAGAGATTGTGCTCATCGGTGAAGTTTGTCTCAAACATGAGTGATGCATAAGCATTCTTTTCATTGACATCATACTGCTTAATACCATATTGTGCCTCCTGCTTGTGCATAGAGACATTACCCATCAAAGCGATGTTTGTGGCGTGTTCCTTATTGAGAACAAAGGCATGTTTCATATAAGCCTCGTAGCGGTCGGTGCCGATATCAATGCGATAAGGATTCGTTGCAGCAGCATGAGGAGTCTGACCACTCACGCGATCTTCCTTCAACAGCGACAAACCAGCATGTAAGATATAATCGCCCTTCTTCCAAAACCAACGGTTCTGCAGGTTGTATTGTCTCACCTTTGGGGCATCTTGGAATCCGTCTCCGTTGCCATCATGATGTAGCCAGTTGTTCTCATAGTGGGCAAGGATTTCCGTACTGAGGTTCTTGTTACCATTGATATGAATATTACCATCCGCATTTGCCTCGAATCTTCCCACCGTATTGCCATAGAGGTTGACGGTCATACCTGTTGGATCTTCAGGTTTAACGTATTCCACATTGATCTGACCTGTCATCGCTTCGTAGCCATTCTTGACGGATGTATTACCCTTACTCACCTGCATACTCTTCATCCAACTGCCTGGAACATAGCCCAAACCGTAAGGGAGGGCAGCACCACGGAAGTTAGGAAGGTTCTCGGTCAGCATCTGAACATACGTACCACTAAGACCGAGAAGCTTAATTTGTTTGGCCCCCGTTGTCGCATCTGAGTAGTTTACATCTACCGAAGCATTGTTGACAAAGCTCTCACCAAGGTTACAGCAAGCAGCCTTGAAGAGTTCGTCACGTAGGATGTCTTTACCGTTGATGGCGCCAGAGAGCGATCTCACTGATGCCTTTCTTGCGGTGACAGTCACGTCAGAGAGCGTCTGATCTTTAAGGGTTGCGGTCGTGTCGACAGCAGTTTCCTGTGCGGTAGCAGGTAGGACAGACAGCAAGGTCAGTCCTGCTAAATATATAATTTTATTCATTTTGTTTGATATTCAGTTGTTTTGTAAAGTTTATAAAGCTTATATGGTATCAGAATGGGAAACATACTGATACGCTTTTTTACCCGAACACACTTGTGTAACAGGTACGATAAACCTTCTGTTGCCCATTTCATGAGGAACAGAAAACAACCAAAAATCAAATAATAAGTGTCGTAAGTAATCGGAGATATTGGCGTGGCGGACTATGCCAGAGCAACGACAATATCCTCTCTGGGGCCTTTGTCAAAATAGGCAAAGGCAATAATTGACAATCACTTACGAATTGTGGGAGAAGAGAAAGCTGTATTGGTTGAATGTGGTAAAAGTCATTGTGCGCCATGTCTGTGGGCGACAAGGTTTTCACCTCAATCTTCATGCAATTTTTTACACCGTTATCATTGCAATGACCTTTATCTTCCATCTTAGCAACAGACACATTGCCAGTATGTGCGCACACCACTGTCATAATGCCCGAACCAATCCATACTATCATCGTTGACAATAGAAGGGATAGTAATATGTCTGTCGTTTTTCTCATAAACTTGGCTGCAAAGTTAGATAATTATTTGTAACTTTGCAAATATTTTAAATTTATTTTAATGTTCAACTACCGCCCTTCAAGGCGAACCCTGTATGTAGGAGGGGGCATTTTGCTTATCCTTCTACTCATATATATTGTCTTTCGTTGTCTGCCTCCTTCACAAGAGGAGGTGGATAAGAGTGCTGTGGCTATCCGTCAGGAGGCGTATTACACGTTAGAGGCTGATGGTAAGCCCCTTGCATACTTTGCTGATTATGTCGATTCGGCGTTTGTGGGTGGCTCTATCAATAAGGATTCGATTCATACACGCAGCATGACGCAACGCGGTTATTGGGTGAACCGACTGCCTGTAGTGCCTTCTTGCCACGGGCGTATTCTCATTCGGTGGAATTACAAACCCTTAATAATCGTCAACTTGAAAGGAAAAGGGGTGCTAAGGCTTATTCGTCAGACGATGGCCCAAATGGATTCGGAGTTAGACGGATTGCAAACGAAGCGCAACGAGATGGGTTATTATCTTCGTGTACATAGCGTTCAGGATTACGGATATAACAAGATTGCGGAATATCATACTGAGGTAGTGCAGCAGATGGATTCGCTTCGTCGGATGATGAAGGTGTTGGATTCTCTCTCTACTTCTTCTGCCCAGCTGCGCATTAGACAGCAAAATCGCTATGCTATTCAGACTTCCTCTAAGAAGGCAAAACCTACAGTTTGCAACCGATTGGAAATAGATAAGAAGAATGATTGCGTACTCTTGCAAACCGAAAGTAAAAGAACGCCAATTCGCTTGATTACTCGCTTGCAGAAAAGTGGGGCGATAGACGCACTGAACACATACTATAAGACCCACGCAGCAACTATCAGCAGCCTTGCAAAGGGCATTTGTATTGCTGGCGGACGATATGAGGGTGAGAGTAAGAAGAACGTTCCGAATGGTTATGGAAAGTACTATGGCGATGATGGCAGCTTCTATGACGGACATTGGAAGGACGGAAAACGCGACGGATTTGGCATCTATGTTGCACCACACGAGTATCTACAAGTGGGTGAATGGAAAGCGGATGTGTTTAAAGGTGAACGCCTTACATATACTCCCGACCGTATCTACGGCATCGACCTCTCACGTCATCAGCACGAGAAGAATAATAAGGTGTATCACATCTATTGGAACAAACTGCGCATTACCGACCTCGGTACGCTGAGTACGAAGACTATCAAGGGAAATGTAGATTATCCTGTTTCCTTCGCTTACGTGAAGTCTACGGAGGGTTGTACGGTGCTAAACACTTATTACGAGGCTGATTATAAGGCAGCACGTGCGCATGGTATTCGAACAGGTACCTATCATTTCTTTTCTACCATGTCACCAGGTGCAGCGCAAGCAGCCTATTTCCTCAAGTGTAGTAAGTTTAACAAGGGCGACCTACCCCCAGTCTTAGACGTTGAGCCGACCGATGCACAGATTGTTGCGATGGGTGGAGCTGAGGTGATGTTCCGCAATATTCGTGCGTGGATGAGCCTTGTGCAGAAGCGAACAGGTAAACGTCCTATCCTTTATATCAGTCAGACTTTTGCCAATACTTACATGCCATTGGCACCCGATTTGGGCGACAACTATCACATATGGATAGCCCGTTATGGCGAATATAAGCCCAACTTCAAGTTAGCTTACTGGCAGTTAAGTCCTGATGGTAAGGTGCGTGGTATCCATGGCGATGTCGATATCAACGTCTTCAATGGCTATCGCAATCAGTATGAGGAGTTCCTTAAACGCCATTGCTTCTAAGGAGAGGGAGAAAGTCATTATACAATTATCCGATAGAAAGGTAGTATAAAGAACGAAATAAAAATAAAGTAAAGCTGTATTAGACTTCTAATGCAGCTTTACTTGTGTCATAAAGCGATAGGAACTATCGTCCTAATGAGGATTATACCTTAGAACTTCTATATTTACTTGGCGTCATTCCTAAGTGTTTAGAGCAGTATCGGCTGAAATAGGAAAGGGAAGTAAAATTCATGATATCACTGATTTGCGTCAGTGAGAGCCTTTCGTCATCAAGATATTTACGCAGTATGGGGATGGTGGCACGGTCGATATAAGAGGTAATTGTTTCTCCTGTGGTACGCTTGACAACACGTGAAAGATACTTCAAAGACACATGCAGCTGCTCAGCAAAATAGGTTGCGTCCCGCTGTGTACGTGTAATACCAGTGGAAAGCATCCTTAGAAATTCGTTGACAACATAATTGGCATGGTCTACGTGCTCCTGATTACGATAATAGATAGTGTGAAATTCAAAGATATCATATATCATCGTAAGGCACAGACTTTTCATGATTTCACGATAAAAGATAGCATCTTTCTCTCCGAGTCTGTCACGAAGTCGTCGAATATCACCGATGATTTTCTCCGTATTCTCGACAGATAGGGGGATAACAGGGTCTTGATAAAGACTCATACTTCCTCTGATGCTGTAATTGTTTGGGGGAAGTGAATTTCTAAGAAAGTGAGTATTAGCAGCGAAACACTCTATTCGGAAATCGTTTGTGACGGCAATATTCTTTACCTCGTCAGGGCGACTTATAACGATAAGGTCATTCTTATTGATGTGAAAACACGACTCGTTATAGACGAAGCTACCCTCCCCACCCATGCAGATAATATGAAAAATGCAGTGAGAAAACCGCTCATCCTCTATCATGTGGATATCGGTTGAATAAGCAAGGTCGAAGTCCTTTAATATCATCATATTGCAAAAATAAGCACTATTTTGGTCTACTCCAAATCTTTTTTGTGTAAAAAGTGAAACAATAGGTAGAAAAAGTGAAACAAACCATTGATTTCTTTTGCGTAATTTTGCACCGTCAAACGATAATAACAAGTTTTGTTGTCGAAGCAAAGGTACAGTCCTTTTATGGGGTAAGATGCTTTTTTACAGGTTGTTAACGATCGAGTTTGAGTCCGTCTAACGACATAAAATAATAAGTAGAACAAATAATTCATTAATAAATAAACAAGGAGAAATATGGAAACAATCAAATTAAGCAACGGAGTTGAGATGCCTCTTTTGGGCTATGGAGTATTTTTGGTAAGTCCTGACGAGTGCGAACGCAGTGTGAGTGAGGCTCTGAAAGTAGGCTATCGCCTTATTGACACCGCCCAGATTTATGGTAATGAAGAGGGTGTCGGACGTGCTTGGCGCAAGAGTGGACTTAGACGTGACGAGCTTTTCCTCGTAACTAAGGTGTGGCCTTCTAATGCAGGAGAGGAGAAGGCTGCTGCAAGCATTGAAGAGAGTCTGCGTAAACTTGATACAGACTATATTGACCTTCTGCTCATTCATCAGCAATATGGCGATATCTATGGTACATGGCGAGCTATGGAGAAAGCCTATCGTAGCGGTAAGGTGAGAGCTATCGGTGTGTCTAACTTTCAGGCAGGACGCTTCTTCGAGTTTGCTCATTATGTAGATGTAAAGCCAATGATCAATCAGTTGCAGTGTAACGTTATGGCACAGCAGAATGATATTGTGCCAGTCTTGAATGAAACCGATACAAAGATGATGGCATGGGGACCACTTGGCGGAGAAGGTGTAGATGGTATTGTACAGAATGAAGTATTGGCTGCGATAGGTAAGAAATATGGTAAGTCTGCTGCACAGGTGGCACTCCGTTGGCTTACTCAGCGAGGTATTGTAGCCATTCCAAAGAGTGTACACGTAGAGCGTATGCAGCAGAATTTTGATATCTTCGACTTCAGTCTTACCGCTGATGAAATGACAGAGGTGGCAGCGCTTAACCAGCAAGATGCAGGATTTATCGACTTCAATAGCCTTTCTTTTGTCAAGTATCTTATTGAAAAATACGGATAAACTTGGCAGAAAACTGATTGAAGGGCTGGGATGTTAAAACGCAAAGCCTAATAATTTGTTATTATCCTTACTCTTCCTAACAGAGATTATTGCGGTAAGTGACTTGTTAGCTTATTAGTCTTTTCACGCATTAGTTAATCGTTGTTTTGTAAAGAAAGTTCAAATCTTAAAAATAAAAAGGGCGTTAATTGGCTTCTAATTAACGCCCTTTTGGCTTGCAAAAGGTGCCCTTTAAGCCCCTTACTAACGCCCTTTTGAAGTCCTATTAGGTACCTTCTGGAAGGCTCTCCCGCAACTAATTGATTACAAAAGACTTACAAAGGCATCAGATTTCCTTGTTTTTAGCTCAATTCCCAGTCTCCGCCTTGCTTACTTTGCAAATATATTTCTAACCTTTGCTGCTTGAGATTTGAACGTCCTTTAGTGGTAACTATAATTGTGGATTAATTATTGCTCATATAGCCTTTTCAACTCCTCCCTATCAAGAACTCTTATAAGGTACTCCGTTACGAAAAGGCGATACTCTTCAGCTGTAAGATTATCTTGAACATCAAAATAAAGGATTGACTTTGTAGAGCGATCGTAAGGTGTATTATCTTTCTTTATTTGCCTTTCAACAGTTCCAGAAATGAATTTGTGCCAGAACACGGGAACAGGATTCTCTTTTGTCCCATATTTAGAATCATGTAGCTGAGTCTTATTTACATGTACCAAGAAGATATTTCCTGGATTAAAATACGATTTAATTCTGGCTGCACCTAAGTCTCCACCACGTTTCTCTGGATTGAAAAAATCAATACCTTCAAACATGCATATCGCAATATATTTTTTTATTTTAGCATCATAAAATGATACTGTGAAATAATATATCAGATTATTATGTTGATCCCGATAATTAGTAACATACTTTCTTTCTATTTGCTCTCTATTAGATGGTAGTTCAATCTGAACAATCTCTGAGTCATTGATATATGTCTTTAAATATTGCAAATTATCTGTATTGCCTGTATTTGCAAAATAACTATATATGGTATAGATTAACGGAGCTAATATGAAAAAACCAATAGCTCTCCATATACCAATAGAGAAAGACGATAGTGTAGTCTGAAACTTTTTCTTATTCATTCTTTACCTAACGTAAATGATACCATACCACCAGTTTGCTTCTCTCTATCTATTGCTGAGCTAAAATTCTCCATCATATCTTTCTCTTTTAGTTTTAATTCCTCATCATACGTATCAGCTATTTTCGTGGCAACAATTCCGCCTATAACACCAAGCGCTAAACCAGCCATATTTTTCCCAAATTTCTTCAGCCCATTACCAGCCTCTTCAGCTTCCTTTGAAATTAATTTTTCAACAACTTTTTGTTGATTTTTTGCATGTTTTGTTGCAGCCTTTGTTCCCTTTGTTATAGCCACCTGAGTTAGTCGTTCTAACCCTCTTTTCTGTGCTATTATATCTTCAGAAATATTCTTCACAGTTTCATATGAAGATTTCAAATCTTTATAAGTTGTTACCCCATCTTTAACAAGTCCTGCTCCTGATTGGATGTCGTTGGAATTTTCTGTTATAATATTATCGCTATATGCTTGGTTAGAATACATCTCTTTATGATGAGAATTTGCTGTGTACCAGTCAAAAAAATGGAAAGCACTGGATATCCCTAATGAAATAGGATTCAGTCCACCAGTAGCTCCGCCAACTACTCCTTGCCAAAACTCACTTTCACTTTTCTTTGAAATAATTTCTTTATTAGCGGATGTTAGCATACTAGCAGTCTCTTGCGCTATAGTATCATCCATTATAATTGCAATTAAACCTCCTCGTGGACATTCAAGTAAGGATCTATCAACAATAGTATATTCACCTTTTACTTGGATACTCTGATGATATATATCCCAACTCATTCCAGATACTACATCGCAGTCATGCTTCTGACTATAACCATAAGCTATACCAGTTATCACGGCAGTACCTGCAGCTATAATAGCTGCTAATCCCAAACTCTCTCCAACAAGAAATCCAACAGCTCCCATTGCCACTCCAGCAAGCCCACCAGTTCCAATGACAAGTGCAACAGCTACAACAACAGCTACAACGGCAGCTACACCTACTAATAGCCCAAATAAGTTGTACATAATTCCTTTTGCAAAACTTTTTGGGACTCTACATTCAAAGCATGCGGAAATCTTGGTATCTTTATAAGTCAAGATAGGGGCAGGATCTGTAGCTCGGTATTGCTCAAAGCGTGGTTGTTCTTCGCACCCTATTTTTTGAGGGGAACCGCAAGTCATGTTTGTACAGACTATATTTGTCCCCAGATATACAATATTAAAAGGCATAGTTCTTATTCTATTTTTCTTAATTTACAAAGAATGGTTAAGTCTATATTGTTTACAACCTCTTCTATCAAACGCACTTCTGCTTTTTCTATATATCGTTTTTCTTCATTGACTGTCTCGCTTATATTGAAAATAGGTCTATACTGATTAAACTTATATTGGATAGTAGGCTTGTATTGTTCATTATAAAACTTAACAATTTCTGGTAGTGTTGCGATATATTCATCTATACTTCCTATTCTGTCATACATGATTTTATCAGAAGAATCTTTATAAGTTCGTGGTGTAATAGTCATTGGAAATGAAATACCTTTGAATAATTGAGACGGAAAGGTTATAATATCTGGGGCATTCTGTTTTTGTTTTCCTACAAGATAGTAGTCGAAAATGAGCATATAAAACATTTTACTTTTCATTTCCGCTTTCATCATTTCTTGATCAAGAATCAATTTATCTTGTGTTTCAAGGAATTTATTTACAGAGTCACGAGTTTCTCTTGACCTAAGAAACTTATATTTATCTCTGAAGTAGTCTTTATAATCTTCCCATGCCAAGACGATTTCTTCATGATTTACAATCTCACCTATGTGACCAGTATCCATATCCACATTTATAACAGCCTGACATTTAATTTTTTCAAGGTCCACAACCATATTCATTCCTGCTTGATACTGTTCAGGAGAAACAGAAGCAATATTATCATCTATTTTAAATGCAATTTGCATAATGTTGTGATGAGTATTATAAACTTTCTCTACGGTATAATCTGTTTTCAACCTATTAGTACTAATGAGCATACCATTTATTTTCATAGCAACGGTTTGCTCATTTCTGTATCTGATATGTTGATATTCAACATATTGTTTTCCTTTAATTTTCTTTTTTAATTCTTCCCAATAAGTCATAATCAAAATCTTAATAGATATTTACAAGAATACCTTTGGTTGTTGCAATAGACTTGTCCACACCGCCAAAGTTCATATTCACTTCACCTTTTTTATGGGGGGTAATGCTACCTTGTAATTCTTCAAGTTTCAGAAAACTGCAACTATGACTGGTGAGTCTTTTGCACTTGTTGCCCTACCACCTACCTCTCAGATAAAGAATGTCATATTCCTTTCTGTCCAGTTCCTATGTTTTTCTGATTGAACTCATGATTAAATAATTTTAGGTTGTTAGAAAAATAATAAATGAGAGTCTCTATGTTATTAGCCCAGCATGGGAATACAAAGAGAAAAAGAACAACAACTTCTTGAAATATCCTCTGTGCAACTGATAACCAGTTTTCTCCTTATAGAGAAGAGGATGATTTGCAATCTGTTTTCTTATATGATAACAAAGATAGAAAAGAATCTCATTACAACAAATTAAAAAACATTATATAACAGATATTTAACATTTAATATAAGTGATAATAAACTTGATTACTATCTGGGAACATGACCAAGTTGCAGTCTATATCTGCAAAGAAAATCAGTGCTCTAATTGTTGTTATGATTCTTTGGGGACGGAAATATGCATATAAGAATTTTCAAATCAGCGAGAAGTTAAGTTTGTCAATACACACGGGATTAATATTTCTTCGTTAAACGTCTGTGTGTTAATTTATAAAGCACAAGTTAAGCATAAAACTGCACTGAGTAAGATTTTCTTCATATTCTACAATTTAGTTGTTAAGTAAATATACATAAAAAGACATAGATTAACGAAAGTGAAAGATTATTTATCTTACTTTTATTTCTCTATAAGTCCTTCTACTGATAAAACAAAAAACAGCTAATAAGCTGCGAGGATAGCCCTCACACCTTATCAGCTGAATATATTTTAGCTGGTATTAGACGGTGCTAATACGCTTTGAGATTACTTCTTCTCCTTGTAGAGGTCCTGGCAAGTCTTCCAACCGAAGTGCTTGTAAAGCTCGTTCAGGCGGGTTTCACGTGCCTTGAAAGAGTCGAAGTCCTTCTTGTCGTTCTCTGTCCAACCAGTCTCTGCCATAGCTGCAACACGTGGGAGGAGCTGGAAGAAAGCGAGGTCGCGACCGATAACATACTCAGTCCAGAGGTTTGCCTGTACACCCTTAACGTGCTTCTTCAACTCAGGTGCAGCGTCGTCTGGCACTGGGTTGTAGCCGTAAGTTGTCTCAACTGGGAGGAAACCACCGATGAGGGTCATCGTGTTATCCTTTCTCTGATAGTAGTCGAGATAGTAGTAGTTTACTGGAGTCATGATGGCATCCAAACCACGCTTAGCTGCCTCAATACCACCGTTCACACCACGCCAGCTCATGACAGTTGTACCCTTGTCTACATCACCCTCAAGAATCTCGTCCCAACCGATGATGTTACGACCCTTAGACTCCAAGTGTTTTGCCACTTGATTCATGAAGTGAGCCTGTAACTGAGCCTCTGCAGGGAAGCCGTTAGAGCCCTTCAAGCCAAGACGTTTGATTTCAGCCTGACAACGTGGACAGTGTTGCCAACGAATACGTGGGGCCTCGTCGCCTCCAATATGGATATACTTAGATGGGAAAATATCAACGATTTCGTCTAAGACATTGTTCACAAACTCGTAAGTCTTAGGGTTACCAGCGCAGAGAATGTCTGGGAATACGCCCCATTGCTCAGCCACTTTGTAAGGACCACCGGTACAACCAAGCTCTGGGTAAGCTGCCAATGCACCGAGCATATGACCAGGCATGTCAATCTCTGGGATAACAGTGATATAACGATCAGCTGCATATTTCACAACTTCACGCATCTCATCCTTTGTATAGTAACCACCGTATGGGGTATCATCAAAGAGTCCTGTCATACGACCAATAACTGTCTGCGCACGCTTTGAACCAACCTCTGTGAGCTTTGGATAGCGGTCAATCTGTGCACGCCAGCCCTGATCTTCAGTGAGATGCCAGTGGAAGGTGTTGACATTATGAAGTGCCAACATATCGATAAACTCCTTGATGAAGCTCATCTTGAAGTAGTGACGAGCGCAATCGAGCATCGTACCACGATAGCCGAAGCGTGGATAGTCAACGATACGAGCTGCTGGGAAGGTTACGTTCTCTGCCTTCTCCAATGGTAATGATTTGCGAAGTGTCTGTACACCATAGAAAACACCACGTGGAGTCTTGCCCTCAACGGTAATATTCTTACCCTTTACGGTGATAACATAACCCTCCTCATTCTCAACCTTTGCATTGATTTTCAAGGTAATAGTACTTCCTTTCTTGTTCATACCATTGAGCGCAATACCAGTTGCCTCTTGGATATATTGCTTCAAGAATTCACCATTACGGCGCATAGCCTCATCGTTGCTTGCAACATTAATAACGGTGTTAGCATCCAAAACGAATGGCGTACCTTTCTCAGCAGTAATACTCTGTGGGAGAGGAACTACCTGGTAGTTCGCATCTGTGGCATGAAGTGAGAATGTAGCCATCATCAATGCCACTGAAAGTAAGATTTTCTTCATCTCGATTAATATGATTTTTGTATTTAGGTTTTTATATTCTGGATTTCAACTATCCATGGACAAAGATACGAAAAAAAAGTGATTAAATACTTGTTGTGGGTAAAAAGTGTAGAAAAACTACTTATACCAGTTTGTAAAGTTCATTTGTTCTCTATCAATACTGGTTATAAAAGTAGAACGAAAAATATTTTTCCAAAATAATAGACTACTCCTATAGGTTATGCTTCCGTGTGTCAAGATAACCTTAAAGAATAATTTTACTGTCACTCCTGTCATTTTTATAGCACACCTAACTCTTTGATTTACAAAGAGTATACGTGAAATGTTAAAAGTGACAGCAAATCAAAACAAAACTATTTATGTAAGATTTGCTGTATTCCCTCACTTGTTAGAGCGCCTTTATCACTCTAAATTTCGAAAGGGCTATGTTTTAAATAACTTCACCTTTTCTCAGAATCCATACTATATTCGGTATTCTTATTTATTCGCAGCATACAGACTATCATTATTGAAAGTATAATAATTTGCATCTCGATTTATCTTCCTTATTATTTCAAAAGCTTCATTTATACAGAAATCATACTCGTAGACTAACAGGGTATATATGTGGCAATATTCATTATAAATGTTTGTAGCAAATATACCGGCATCATCTGTACCTAAGACTATTGGAGGAATTGGCTTCCCTTCCTTCTCCCATCTAATCCAATTTACAAGATGATAAGTATTAAAGCTATTGTGATAACCTATGAAGATATTACTCGTAGGGAGAGTTTCAATAGCTATTTCTTTATGGTGCATTATCTTTAAGATAGCTAATTGTACTTCTCTCAGAGCATTCTTATCAAGTATCTCGAAGATTTTTACCTTTATCTCCTTTTTGTAATTTTCAACATACTCTTTTTGATGGTATCTCTTCAAGGCCTTAATATTATTTAGCTCCCCACTATCTGCCAATTCTAATATATCTTCTTGCCTTTTCTTCCACGAATATATAAGATCATAAACTTGAAACTCATCATTAGGGAAAATCTCTCTTGATAGTTCCGTTATACGCATATATAACCGTGGCATTAATGATTCTAAAGCCTTACATTCATTATTGCTAATTAGATAATATACAAAGAGCAGATCATCCATATATGCACCTATTGGCACTACAACTTCACACCCTACATTGTGCTCCCATATTCCTGGGTCAACACCAGCTGCCGTTGCATGTCCGATTCTATCACCTCGCTGTAAATCCAAGAAGGTAATTGCTTCATAGATAGCGCGTAATCCACCAAGTAGATGGTAGAAGTCTTCACCAGCATGAAATGTAAAATATTGGAATCCGTTCTCACGCAACCGCTTAAACACTGGGGCAAACACCTCTGGTGGTGTGTCAAATTCGCTTGCTGCTGCATCTATTCCGACAATAGCTCTCCCATTCTTACTACCACTATTACGTAATGATATCAGTGCCTCACATATTTTTCTATTCTTTAGTCTTAGTGCTTTAAATCGAATGTCATCCTTTCCTTTATCTGCCCGCTTTATAAAATGGGCTGTGAGCCTTATATTCGACTTATCACAATCTTGCCTATTATTTAGATGTAACCATCCTCTTCGAATTTTATCAATTAATTGATTATTCTTTTCTATTGAATCTTTAGGTGAGAATCGTCCTTCTAAATTCTTAATATTATCACACTGATTTCCAGCCAACTGAAAGAAACGCTCTATATATTCTTGCTCGCTATACTCTCTTAATCCATTTGATGTATATTGTTGGAACTGATCAAAGCCAAAGCATTGAGGTTGTTGAACCGACATCTGATTGACAAGACCCAGTATGAGCAAATAATGATGAAAATATGCTGCGCCTTGTTTGTTTTCAGGATTCATTGATAGATAGTGTAGCACTGCAATATAAAGACACGCCTCTGATTGTCTTGTAAAAGATTCTCTCAGTTGCACAACTTTGTTAACCTTAGAAAAGAGTTTCTTTCTAAGTTCGATGGCTTTTTCTATTAACGTTTTGAGTCTCCTGGGTTTTGTCCAATTATCAAACTGCTCATATTGTTCTTTGGCAAGTTCATTTCCGTTTGAACTTTCTAACATCTCACGATAGAAGCTATCAGGATAGTGTAAGAAATCAAGCCAAAGAGTATCCGTCTCCACCGTACCATTTAGATGAATATGCAAATCATTTAATCCATGACTCTCCTTCTTCAATTCTTCTAATTGGGGTATGTATGGCGGTATCAAACTCGTATTTCCCAGGTTCGGCGCAATAACCTGATTGTAAAAAGAGTGTGACCCTATATCATTAATAGTTGAAACGAGATTCTTAAAAATAAAAGCACATATCAATAGCATGGGAGGTATATACGCTATTTGTTCTTGCCAAGCATTAAACTTCTCTATTTTGACGTATATGCGATTGTTTCTCCATTCTAAGAAGTCATTTGCAAGTTGGGTTAATCCCTGTGTAAAGAGTTGACTTTTTGTATTTATTCCTCTAAACGAACTATCAGACACAAGCCTCAGATAATGGTGCGGTATCACATGATTGTCTTCCCGTGCTATTATCATAAGTCTGCGCTTAACATCTCTCAATGAGACCTCTTCCCCTTCCTGATAAGAGGAAAGGGAAAGGCGGTCGATTAAAAGGTATGATATGTGTGAATTACTTTTCATGTTTCAGATGGAGCTAATCATCTTATTGTTTATCAATGTATTCTTTCTTATATAGGTCTTTTAATCTCTTTGTACAGCCTTGACCAACACTATTCACGAAAGGCAAGCTCTTAAGTGCGTAGTAGGCTTTTAAATTATCTACGTCATAAATATTTGTTCTAAAGAATTCTTTATCTTTTTCTTCCATAATACGTTCCAATGATTCTTTTAAGGAGTTGTTAGTAATATCTATTGTTTTAATTAGTGCATTCTCTTTTGTTTCAAATTTGGCACGACTCAATATATCGAATAAAGTTATGTCGTTAAAACCAAAGTTCTTAATATGTTTTTTAATTTCTAAAGAAACTTCTTCTTTAAAGAAAACACTAATTAGAGGGCAAGATAATAAACAACGTATAAAAGTAAGTGAATCCAAATAGGATTTCTCATCTTCGTTTATTTTTGTTACTTTTCCCAAGTTATCATAAAATAATTGGGGAGTACCCACAGGATTGTTATTATTGACATCTACTTTGTTATCAAACTTTTCTTTGACTTCTTCTATCATCACAGAGTTTAAGAAAAGTATTAAATGCTGTTGGAATAGTTCTGCTAAATTCTCTTTATTAGATACATTTATCAAAGCAGAAGTAAACCGAGTCATGATACGCCCTAACAAATAAGGAGGCAGTAAAAGAGTTGGATTTTTTTCATTATCTTTGATAAAGGTTTCTCTCCACTGGATTAATTTTATTATTAAATCATCTAATATCTCATCCTCAATGTCTATACCAAGACTTTGTGATAACTCTTCATTTGATGTAATGTTACTTTCAGGGTCGTCAGAAACAACTTGGTCTGCTGACGACATAGGATAAGTGCGATGCAAACTTAAATCACTAAGCAAGCCCTTGATAGATGATTTATCTTTTCCTGAACGAATAATCATGCATATTGTCGACAACAATGGGAGTACGGAATAATACAATTCAGTATTTTGACGTTGTCCTTTTCCCAAAGAAAATAATGGTAACAAAGCTAACACCTTTTGTGTCATATTAATATTATCACCTTTGAGAATGTTATCAATCGCATTCTCTTTTTCTTCTTGGTTTTTTTTCGCCTTGAAGTTAAGTCCTTCCAAGCGTATGAGTTCTGGCAATTTTAGATTGTTTGCTTTTCCAACCGCAGCCATTAAAAGCACTATATTCTTTATTGACATATCTTGCATGATGCCAGTATGCGACAATATTTGATTAAAGGCAGTTGTGCTTAATTGCAAATTGAGATGTCTGGTATAACCAACTCTTAACATATAGTCGAATATAATCCATGGGCTCTGTTTAACTTGGTTAGCAAATATAGTAGTCAACCCCATAAGGACACCATTCACATCATGATTCAAGGTATTAGGAATAAGCAAATAAGAATGAGCAAAGCCATTCAACTTTTTCAGATATTCTACAATCGAGATAATTGTAAAAACAGGATTCTTAACAGCAAGGTCAACATCAATATCAGCAGCCGTCATACGTGAGACATATACATTAATCTGACTCATAATATCAGGTTCATTATAATCTGAAAGTATGCTTATCTGACTACGAATAGATAGACCTAACAGGTAGTCGATAAATAACTCTTGAGTTGAATTCTTATGAATACCAAGACCATTCAGAATGTCAATATACTTTTTTTCAATATCTTTCTCTTTATCCTCTTTTTTCTGCTTAACCATATATGAGGTATCATTGATACGCTTATAGTCAAGCAATGTCCTCAATTGGATTCTATTTTCTGGTTTAAGCACCTTTAAGAGATATTGTCCTTCCAACTGATTTACTTGACTTTTATAATCGTGATCTTCATGCTCTTTCAAATTTTTTAATTGATTCCATTGGTGTAAACGGACATTATATGAATAGAGCGTAGGATTTCCACTAAGAAGTACGACAAACATAGGTGTTGTAAGATACTTACGTATAGTTTCAAGGACAGGCCATCCTTTTGACATATCGACATCAATGTCATCAAAAGCTAAAACAAAGAACTCTTTCTGAAGAATTTTTAAGGCAAGTTCTGTCAACTCATGGAAGTTTTTCTCCAAATCGTATGCCGCCTTTACATTCTTTAATCCACGCTCAACAATGTATGAGTCATCATCCCAATTCTCGTATTGCTTATTATTTAGTCCCTCAAGTGTTGGTAAACCCTTAGCTAAAGAGCTTAACTTATTATTCCATTCCCTTTCATAGCAACAGACGCCACTATTATAATTTCTTTTGTGAGTCTCTATTTTGCTTCGAACTTCTGTATCAATCAATGACAAGATTACTAAGAATACATGTTCCTTTTCTTCCATTTGAGTTGGGTCAATAATCTTTAGTATCTTAGCTTTCTCATAAGTTTTTTCTATTTGCTGTAATATGCTGAGAATAAAAGTTGTTTTACCAGTACCTCTATTACCAAAGATTGAAATGGTATTGTATTGGTGATCCACACTATAGATAGACTTTTGGTAACTATTCAGCGATAATAGATATATAAGTGCATCTCAATTTCTCAAACCTTAAATAAGGCTTGAATCGCATTATATGGAGTTTTGTCGTGCTTCTTAGCTGTTTCTACAATCGAATGAAGTTCAAGAAAAGCGTCTGCTCCGAAGTCTGAACGAAATGTACAGGAGTTCTTCAGTTTGATTTTTAGCTTGCGTATTCCACGTTCGCTTCCATTATTGTCAAATGGTATCATCGGATTTTCAAGGAAATTGAAAATGTAATCTCTGCATTTGACTAGGGCTTTTTTGAACGTAATAAACTTTTTACCAAACTCCTCTATATTCTGTTTGAGCAGATTGTCTAAACGTCGGGTCCATGACACCTTGTCTATAACGTCGTTCGGATTGCTATTCCGCTCGTGAATGGCTTCACGGAACAGATTGGTTACTTTCCCAGACCACTCTTGCTCAGTGTTCAACTCTGATAGATATTGCAGTTTGCGGAGTAAGTGAGCAAGGCATACCTGGTGATTGAGGAAATGGAGTGCAAAGTATGCGCTATGGCGGTCGGTAACGGCAGTCATTCGTTCCAAGCTATCGCCAAATTTGTCTACTAATACCTTCGATCCTCTTCCATCAGCACGGAAAAGCAGTGTGTAATAAACGGTTTGTGCAATCCATGCCCAGTCGAGTCTTTTCTTACAGTACAAGCCACTCTCATCGAAACCAACAACTGCTGATGACTTGATATATTCTTTAATTTTATCAATCACAGGTTGCGCATTTCTCTTTGCCTCATTTACCCAGTTCACCAGCGAGCCTTCGCTTGGAGTGAGTCCAAATACCTCACGCAAAAAAGTTGCTATGCGACCATAAGGAAGAAATTGCACGACACTCAGATAAACCACTAAGGTCTTTACGCTTGAATCATATACCACGTTGTTTGACCGCCGTCTCGGTGCTGTCCGAATACGTTCACCACAGTTCTTGCATACCATCACATAGTGTCGGATTTCCTTGATTACGGGCTTCAACTCTGGAATGGAAATAACCTGCGTCACATAATCAAGCACACGTTCCGTATCTGATAAAGATTCTCCGCAACGAGTGCAATAGTTGGGTACCTCATCGATTATCTCGTCAGGTATGGAAGAGCAAGACAACTTATGCCCATCATGCCCCTTTTGTCCTCCCGGCTTCTTACCACTTGGCTTACGGAGGCTTCTTGTTCTTCTGATAACCTCATCCTTTATACGCTCCTTGCTTGGCGGAGTGCTGCTGTTATTAGAGTTTTTGTCAGGTTTTTCATACTTAGCCAAGCGTTCCCGTAAGTTTATAAGTTCCGTATCTTTCTTGCGAATTTCAAGGTTCAGAGCATTTATGTTACGATTCAATTTAATAATCTCGGCATACTGCTGATTGACAGTTGCACGCAATAATCGCATCTCTTCCGTCATGGCTTGTAATACTTTTGATATGTCCGTAACCTGCTCTTTTATAGGTATAAAGGTACAAATAAAATCTGAAATACGCAAGAAAAATAAGTATCTTTATAGCCTTTATACGAAGATTTTAGAGGAGAGAATACAGACTGAACAATACCGCTGAATAGTTACGACTTTTGTCCACCTTTCTTGCTAACTTGATTATCTATTAAGCTTAATACACGATTAAAATTAAAAGAATGGATATTATTCTCTTGATTGAAACCATGAGCATATTTGCTCTCTTCAAGACAAATAGTTATTTGTTTTGGGATAGAGGGTAGGTTGTTTGCCATATTCTTTTAAATTTATAATTATATTTTATTTTTCACTTTTAGATTTATCATTGAACTTTTAGATACCAGCATAAACTTGAGGTCATGGGAAAACTCCCTAAATCTTTTAAGTTATAATCTCGGTTTCTCAGTCGCATTTCTATGCTTGTAGATATTATATATCAATGTTAGATATTCTGCAAATATATATAATTTACTTGTAATTGCAAAATATTTAGACAGCATTTTTCTAAAATAACATTACTCCATGTTTCAGAAGAGTCCTAATAAATTTCAGGTCTAAGCTTACTCTTCAATCTCAGAGAGACTTCTGACAAAGTTACTAAAGAAGTTGCTTGTTGTCTCAATGGGTGCATAGCTAACGTAACGGAGACTGCGACGGACGTTGCGACGAAGTACGGAACTGTTGTTTTGTACAAATCCTACGACGTTTTGTTTGAAGTGCCATTCGTGCGCAGTGTCCTTCGCTAAGTCTGAAATACTGCGTAATGTGAGGCGGTAAGCATTTGGGTCACTCTTGCTAACGAAGGGGATTTCGTCTTCTTCAAATCCAAAGACGGAGATGAGAACATTACCCTGTAGCTCTGCCATAGCACTCAACTGCAGGGTGTTCAGCCAGTTCTCGAGTTTCACGAAGTCTACCTTATTACCCCGAGTTCTTAGGTATTCGCCCATCGTAATGATACCACCTAAGTTCATACCACGTGTAAACATCGTCTCAGAGTTGTTGACTATCAGCTTCAACATATCAATAGCCTCAATCGAAGTGTCGATACTATGCAGTTCGTTGTAGATAAGATTCTTTAGTCTACGGTTCAGTAACGCATTGCTAAGTCTAACTGTCTTGGGTATTCTTGCAGTTAATGTCTTGCGTTCTTCCTGCTTTGCTTTGATGTCTGTGATGATACTCTCTGGCAGGTTGAGGCCTTCATCCATAGCGTGTCTTGCGATACCATTGATGAAGATAGGCATCACTTGTTGTGCTTCAACCATCTGTATGAGTCTTCGCCATTTGAAAGGCGACATCGGTTCGAGGTTCGACTGTGTGCCGAATGCGCCCGAACAAAGGATTCGAAAGAAGTTACGTTGAATGATGTCCATTCCAGATGATTCTATTGGTTGCATGGTGATTGGGTGTTAGGTGATGAGTGTTGGGTGTTGATGATATGTTTATGGAGTGGTGAATATTGGGTGATGATGATATGTTATGAATAACGACGGGGATAATGGAAGAGGATAGAAAGGAAGGCTGTGATGCCCAATAACATTGGATAATACAAGAATGGGACGATGCTCACAGGGTTAATCTTTGCCAAACCTGCTGCCATTAATATCTGTGCACCATAAGGAATCAAGCCCTGCGCACAACATGAGAAGGTGTCGAGGATGCTAGCTGCCTTACGTTTGTCTACGCCATAGCGGTCGCCTATCTGCTTTGCAATACCGCCCACGGTAAGGATTGCCACCGTATTATTGGCTGTACAGATATCCACCAAACTTACGAGGAAAGCTATTGTTAGCTCTGCTCCGCGCTTACTGTTGACGTGTCGGGTGATCATCTTGATGAGATAGTCGATACCACCATTCTCACGGATAATCTCTAACATACCACCTGCCATCATCGTGATGATAATCAGTTCGCCCATTCCTTTGATTCCTGCGCCCATACTTCCAAACCAACCATAGACATCGTAGCTGCTATCAATGATGCCGATAGCACCTGTGAGGACGATTCCAATGGTCAATACAGCCATCACGTTCATACCAAAGAGCGCACAAATCAGTACTGCCATGTAAGGAATTACTCTGTAGATGTCAACGTTGGCAACCTGTCCTGTGGTATGTATGTCTCTTCCCAAAAAGATATAAACAAGCAGAATCAAGACTGCTGCAGGGGCAACGATGAAGAAGTTTACCCTAAACTTATCTGCCATCTTACACTCCTGTGTTCTCGTTGCCACAACGGTTGTATCGCTAATAAACGAAAGGTTGTCGCCAAAGAACGAACCACCGACGACGGTTGCGACGACAAAAGGGAGCGAACTCCCCGTAGAAGTAGCAATACCTGCTGCGATAGGGGTGAGTGCAACGATAGTTCCGACGCTCGTTCCGATACTCATAGAGATGAAGCAAGCAGCGAGGAAGAGTCCTGGCAGCAGCATGTTATCTGGTAGGACGGAGAGGGTTAGGTTGACCGTAGCGTCAATACTGCCCATGTCCTTAGCCGAGTTGGCGAATGCTCCAGCAAGTACGAATATCCACAACATCATCATCATATTGTCTGTGCTGGCTCCCTTGCTGTATATCTCAATTCGTTTTGCGAGTGGATAGCCTCCTGATATGGCGATAGCAAAGATACTCGAAGCCATGAAAGCCACGGTAATCGGTACCTTATAGAAGTCACCCGATACGATTGAAGTGACCAGATATAGTACGATGAATACAAGTAACGGACTCAACGCGAGGAGTCCTTTTTTGTTTTCTGTCATTTGTTGGGTGTTGGGTGTTGGGTGTTGAATGTTAGGTGTTGATGAATTGTGCAGATGTTGAATGATAAATGATGAATGTTGGGTGTTAAATGTTAGCTGTTGAATGTTATGTGTTGATGATTTCTATTAACCTATTATTCATATCCCTTTTCACACTTACGATATCTTATCTTAAGCATCCGCACATCATGTGCTGAGCCTCTGCACATTATGTGTTAACCCTCCGCACGTCATGTGTTAAGCATCATCACCCTTTTTATCAATGCCATCTTTTATTTAATTTCATCCCCCTTTTACTAACTTTCTTTCATCTTCTTTATAGCAGTCTTGCCTCCCTCCCCTTCGAAAGAGGACTAAGGTGGGGCTTCTTCACCACCTAATTCTTAGCAGTTTTGCCTCCCTCCCCCTTCGGGGAGGGTCGGGGTGGGGCTCCCCCTTTTACCCCCACGACCTATGATAGAAGTCTATATTCTCTCGCATAAGCAAGTCGATAGGCATATAGTTGACTGGTTCAACCTTCTTTTTCAGCACGATAGCACGGAAGAGGGAGTCAACACTGAAGTAGCCTTGTTGGTAGGCATGCTGTGCGATGAGGAACGATATACTCCCTTCTCGTAGGCAGTCAGCATTCTTATGTACCACGTCATAGCCCATAATCTGAACGTTATGGCGATGCGTCTTCAGTAGGAATTTACCCACGATATGCGCTTTAGAGTTCAGTGTGATACAGTGGTGTACCTCTGGATGCTCGCTGAAGAACTTTTCTAAGATATGGTCATAACGCTTCCGCTCCTCGTCTAATGGGAGGTTTACCTCTAAAATCTTAATATTAGGGAAGTTCTCTTCCATATAATGACGGAAGCCCACCTCGCGATTCTCTTGCTGACGACTTGCCATCTTTCCGTCCTTCGTCTGCTTCATGAGCATGATGCTTTCCTCCTTTTGAGCAATGAGCATCAGCATTCGAGCAGCAAACCGACCACTCTGGATAGAGTCCTGTCCGTAGAATGACAGCGGTTGCAGCGATGGCATATAAGAGTCGAGCAGAATGAAAGGGATGTTGCGATCGTGCAGTTCGTCGGTGAACAGGCGTGTCACCTCTAATGTCGTAGGGACAAGGATAACGCCATCCGGATTCTGCCTAAGACATTTCTGGTAGGTCTCGATAAAAGAGTGAGGGTCCAATCGACTATAATACATGATTTCCAAGTCGATATAAAAGTCTCTACGTGCCTCTACCGCCTTCATGGCACCAATCTCAATCTCTTCCCAGTAAGCCTCACTGCTGTGCTTTGGAATCAAACAATAAAACGTGTAACTCTTGTTATAAGCCAGTGCACTTGCATAGACATTCGGCTGATAATTCATCTCCTTCAGCACCTTTTCCACTCGTTTCAGTGCGGATTCCGATACATTCGGGCGTTTATGCAATACTCTATCAACTGTTCCAACACTTACACCTGCACGTTCTGCAATGTCTTTGATTCTTATCTTTTCTGCCATAAATATGGGAAGTGAATATAATATTTTTGCGCTGCAAATTTACTAATAATTGTTGGAATGTGCGAAAGCACAACGTTAGAATTTATAAGTAAAAGTTCTTTTTATTATTTAATTGTGTACAGAATAATGGATAATAGGAAGTTTTTAACTAAATTTGCGTTCTGAAATAAGGCTACGTGCAGTTATGTCTATTAAAAGTTATCTTCAAAAATTGTCTTTTCGCACAGGTGTTATCGTACTCCTGATGTGTATTCCCTTTTATATTCTTTCATTCGTTCAAGTGTTTTTCCCAGTGTCAACGGCAACGAAAGGCATACTGTTTACTGTCTTTTTCGGACTGGCAAAGAGCTTTCAATATGGCGGTATCGCTATCCTTGGAAAGGAAGGCTACAAACGCGTGAAGGGCTATCTTAAGCGAAAGAAACAGCTGAATGATAAGATTATGAAGAATGATAGCAACAGAACGCATCGCTACTGTCCTGACCTTTTCTCCAATCCAGAGATACTTTCTGGTATTCGTCTCATCATCTTCGACTTCGATGGAACGCTTGGCGATTCTCAAAAGCTCATTACCGACACGATGCTTGCAACGATAGAACGCCTGAATTTACCGATGAAAAGTCGTGAGGAATGCGCCCGAACGATTGGTTTACCATTGAAGGAATGTTTTTCGTCTATCATTCCAATGAGCGATGAACAGGCTGAGGAGTGTGCTAAGGTGTATAGCGAAATATTCAATGAGAAGAATGTTCCGGGTGTTGTAAAAACCTTTCCAGGTGTTGTTGAAACGTTGGAAAGACTTTCTTCGCAAGGCATTCTGATGTCTATTGCAAGTAGTCGTAGCCATAGAACGCTTGCAAAACTGATGGACGAATTAGACCTCTCGAAGTATATCACTTATCTGATTGCTGCCGACGATGTTGCCGAGAAGAAACCAGCAGCTGAATCAGTGCTTAAGACTTTGCGTCATTTTAACATCGAAGCACACGAAACCCTCGTCGTTGGTGATACCGAATTCGACATTCTCATGGGCAGAAATGCAGGTACACACACCTGCGGAGTTACCTACGGTAATGGTAGTAAAGAGAGTTTAGATGCCGCAAAAGCAGAGTGGATAGTTTGTTAAATAATGTATAATTCTTTGGCGGTTTCGTAATAAACCACTACCTTTGCACTCGCAATTCAGGAATGCACCTCGGTTCATAGATGAATTGTTCTTAATTAACATCGCGGGTTGGAGCAGTTGGTAGCTCGTCAGGCTCATAACCTGGAGGTCGCATGTTCGAGTCCTGCACCCGCAACTTCAAAGCTTAGAAATACTTAGTAATAAGTTTTCTAAGCTTTTTTCATGTCCACCAAAAACTAATATTAATTCACAATTCAGAATTCATAATTCATAATTATGATTACTACAGTAGTATTGTTGACAAAATGCAAAAGACATAATAATAAAAGACATGGTAACAAAGTAAGTAATTATACAGTAGTAAGGTACGTAAAGATAGGGTAACAGAGTAAGTGGAGATATGTAACAACAATAGTCCGTTAAATTTTCGCAGTTTGCGAAGCTTTTACCCAAAAGCCAACAGGAATTGTGGCAGAAAGAAAACATGATAAGTCTCTGAGAAAGAGATAATTAGGCAATAGAATATAACAAAGTATAACATAATAAAATCGGCTATCTCATTGAATTTCAGTAACTTTATAGATGTAAAAAGACAATAAAGTTTATGCTGATAACCAACTTGATTAGCCGATATATGAAGCTCTGCAAAGCAGCATTTAGTGCTGAAGATGGAGCAAAGTTAAACAAAAGTATTCAAACAAACGTCATGGAAATGCTTTTTCTTTTGATGGTCATCCCAAGGAAATGTAATTTTACGCAGATGGGACGCTATGGAAAGCGTGGCGAACAATGCTATCGGCAGACGGCAGAGCGCAGCGTGAACTGGCTCGAAATAAATATGTGGCTGAGTGCTTTCGCCTTCAAGCAGGGTAAAGGGCTCAATGCCATCGTTATTGATCCAAGCTTCATCAAGAAGGCTGGGAAGCATACCCCATACGTGGGTACGTTTTGGTCGGGCTGTGCAGGTGCGGTAAAGCACGGTCTTGAGATCCTCGGCATCGGTGTGATAGACGTGGACTTGCATGAGTGTATGATGCTCAAGGCTGTGCAGACCACATTGGAAAAAGGGGAGGAGAAAAAAGAGATGAGTCTATACGACTGGTATACCAAGGTGTTGGAGGACGACAAGGTAACCTTACAGCATATTTGCAAGGTTCTTGTCGCCGACTCAGCCTTCTCCAAAAGGCCTTTCATCGACAAGGTAATGAAGATGGGCTTCCATGTTGTGAGCCGCTTGCGTCATGACGCAGCCTTGTTCTACACATGGGATGGGGAACCCACGGGAAAGCCCGGCCGTCCTCGTATCAAAGGTGACAAGATTGACGTAAGGAACATCGACATATCCAAAGGCAATGAGCTTGATTTAGGAGAGACCAAAGGCAAAGCCTATGCGCTCAAGGCGTGGTGCAAGTCCTTGCATAGGGTCGTGTCGATTGTCATCCACGAGTTGCCCAACGGTGTCCGCCGTTTGTACTTCTCTACGGATGAGAGCATGAGTGGACGCGATGTGATGGAGTACTATACCACACGTTTCCAAGAGGAGTTTTGCTTTCGCGACGCAAAGCAATTCCTCGGTCTTACCGATTGTCAGGCACGCGACAAGAGAAAACTTGAATTTGCTTTCAACTCTTCATTCACAGCACTCAATGTGACCAAAATCATGTGCAAGGAACTTGGCACGTCCATCGGTCGACTTAAAGCGCAGATGGTCAATGCCTACTATGCACAACGAATTATTGACGTGTTCGAGAAGAACCCGAACACGCCATTAAATAAAGAAAGGATAAATGATATATTTAGTTTCGCTGCTGATGCAGCATAATATTTAACGGACTATTGTAACAAAGGAATCGAAAGAATTGTAATACGACAATGTTTTGCTTCTGTACGAGCGGATATAATGTAAATAAAAATCATAGACTGAAAACGAGAAGGGCGTTAATTGGCTTCCAATTAACGCCCTTTTGGCTTGCAAAAGGGTGCCCTTTAAGCCTCTTACTAACGCCCTTTTGAAGTACAATTAAGCACCTTTTACTTTATTACTTTATAACTAATTGATTTCCTGCAGGTTATAAGCCTATTCTTTACGCATGCTTTTCCCCTTATTTATAGATGGTTTACTTGAAATAATGTAATGATTTTTCAGAACCCTATCTGCGGTTTTTAAAGTATCAAAATGAAAAGGTTTTCTGTGTCGAAGGATAATAATAAAATAGGAAGATGAGCGCCTTAGTCATGTCTTTATTTAATGAGTAACCTCGCTTCTTCCGTTAGTGCTATACGAAATATATCTACGCATTTAACGGAAAAACCATTCTTTCGGGTATATAAAAAAGAAATGTAGTAAGTGATAGGGACTTATTCACACACCTAAAACTTACTACATATATTTTCTTTTATCGCCTATTCAAAGTTCAATTCACCAAAGAAAGCAGGACAATGGAAGTCGGGAGAAGGCAAGGCAATGGGATTCCATGAGAGGAAATGAGGTTGCGATGTCTTGTCACCACACTTATAGAAATTGGCTCTTATCGTCTTTCCTGAGAGATTATCCAGTGTATGGCGGAAGTAAGAACTAACAGGAACAACGAGTGTGAGTTCCCATGCCTGTCGTCCCTCTCTCATCTCAAAAGGCTCACGACCCAAAGATGCCCAACGATCAATCTGCTCTAAGGCGACTGCTGGAGCATGAGTACGATTCTCTCGTCCCTGTCCATTGCATAGCAATACCGTACCGATACAGTTGCTTTCAAGGTTATAATAGCCTCCTTCTTCATCAGGGCTGCAGAAGAACTCACAGCATGAGTCCTGCCAAACTGGACCTAAATCGGTGCCAGCCTCAGCACGCACGCAGTCTTCTTCTACTCGATAATGCAACAGAATAGCATCATCTTTATGAGCAATAGCAAACTCAACCTGTGGACAATAAGGGAATTCTGCTGCCCAGTCTACTGTATCTATCTTATTATAAGATACGCTATTATCCTTGAAAAGGGCTGGAATGTCAGCAGCTTTCACCTGCTGACACTCCAAACGTTTTACCTTTAATTGTTTCATTGCTTCAATGTTTTCTTCACAAAGTCAGCCATCATCTGATCATGACGACGTACGTCACGATAGAGCAAGAGCTGATTACGTGAGCGAACAAGGTTATGCTCTGGGTATTTCACCTTGAAATAAACGTCTCCGTTGATGTAATCTGTCAAGAAACGAACGCACTGCATATATGGGAACAATGCTACAGCGTATGGCAAGTGACTGGTCTCTACAGGGGTAAGGAAGTTGCCTGCCGTACTAAGATAGCCTTCAGTAAATGAGCAGAAGACATCTTCTTTCAGTCCGACAGCATCGTAATTGTCGCTATCCTCAGCCACATGGTTAGCGCCAGTGCGCAAGAAGTCGCCATAATCAGAGAAGATAAAGCTTGGCATTACGGTATCGAGGTCGATAACACAGAGCACCTTACCATCCTTGTCAAACATCATATTGTTCACCTTTGTATCACAGTGGCAGATACGCTTAGGCAATGCGCCCTCACGATAGAGGCGTTCAGCAAGGCACATCTCGTCTGCATAGCTCTCTAACTCAGCAATCATATCCTTCACAGAAGCCACTCTACCAGCCTTATCAGCACTTACAGCCTCACGCAACTGGCGCAAACGAAGTTCCATGTTGTGGAAGTCAGGAATTGTTTCTCCCAATGGTTCCTTCAAATCAACCAACATATTCTGGAAGTTACCGAAGGTTTCACCACAGCAGAAAGCGCTCTCTGGGTTTACTTCCTCTTTTGTAACAGCGTTAGGAATGAAGACACTCACACGCCAGTAGAGGTTGTCAGCATCCTTGTAGTAGGTCTTACCGTCCTTAGCCTGTACGAAACGCAGACACTTACGTTCGATATCTGTCTCACCTTTCTCTATCAATTTGTGACGGATATGGTCAGTTACAAGTTCGATATTATGCTGCAACAGGTCTACATCGGTGAATATGGCGTTGTTAATACGCTGTAAGATATAATCAGGCGTATTAGCATCTACAGTTTTTACACGCAGTGTTTCATTGATCAGTCCATTACCAATTGGACTTACACTCTCAACAGTTCCCTCAATACGGAACTGTGATACAACATCATTAAAATTAGGCATAGTTATTTATTAGTATTAAAGATTTATTCTTAAAAGTGAGGAGTGAAAGAGGATTAAAGGAGTAAAAGAGGAGTTAAGACAAATGTTATATGGGTCATAACAAACTTGTTTTACTGTCATCGTAGAGATATCATCAAAATGAATCTACATTACATTTGTCTTAACTCCTTTCACTCATTACATCCTAACTCCTTTTCTTATGGTCTATCAGCAGACTTAACACCAAACTGAGAAGGCTTGCTACCCATTACAAACTCAAGTGTTCCACCACGTTTGATGTCCTTGAAGTCGATGTAAGAACGGGTATAAGGCTTGCCATTCAACTTAGCACTCTGAATATAGATATTCTTATCGCTGTTGTTATGTGCCACAATGCGGAAGGTCTTACCATCTCCAACGTTCACCGTAGCCTCATCGAAGAGCGGTGTACCGAAGATATACTTGCCACCTGCAGGCTCTACCTGATACATGCCAAGAGAGGAAAGAATGTACCATGCAGACATCTGACCCACATCCTCGTTACCACTCAAACCATCGAAGTCGTCGTGGTATAAGTTCTTAAGTACATAGCGAATCTTATCCGCTGCCTTCCAAGGCTGACCTACATAGTTGTACATATAGAGGATATGATGGCTTGGCTCATTACCGTGAGCGTACTGACCAATCAGACCAGTGATGTCTGGTGAAGCCTCTGCTCCCATATCACCACTAACGATGAAAAGGGAGTCGAGTTTTGAAACAAATGGTTTCTCACCACCGAAGGCAGAAACAAGACCATGCACATCGTGTGGAACAAGCCATACATACTGCCATGCATTACCCTCTGCATAGTCGTCCTGACGATGAACAGTACTGAATGGATCGAATGGTTCACGGAACTTACGATCAGATGTTACACCACGCATAAACTTCGTCTTCTTATCGAAGTAGAAGTCACGATACGACTGACTGCGCTTTGAGAAGTACTTATAATCAGCTGTCTTACCCAATTCCTTGGCGAGTTTTGCAATACATGCATCAGCCAAAGCATACTCCAATCCCTTTGCTACTGTCTCATGCTCTGGGTCGAGATCACAAGGAATATAACCATACTTCTTCAACAATCCCATACCACGTTCATCAAGCATAGCAGACGCCTTAGCAGCCTCAAAGACTGCATTCTTATCTACATCAAAGCCTTTCAGTGCGATATCAACGAGGGCAGGAACGCCTGGGTTGCCAATCATACAATCGGTTTCGTTACCCACAAGGTGCCATACTGGCAACTTACCCTGCTCCTTAAAGACATGAAGCATCGTCTGTGCGATGTCGTGTTGCTTCTCTGGATGGATAATCGTCATCAATGGATGCGCTGCACGATAGGTGTCCCAAAGTGAGAAGGTGGTGTAATCAGTGAAGTCACCCTTATGTGTCTTACCATCTGCACCACGGTATTCGCCGTTTACATCATTGAAGACAGAAGGTGCAATCATTGAGTGATACATTGCTGTATAGAATATCTTTCTTGCACTCTCGTCCTGTGTCTTGATTGCAATCTTGCTCAACTCACGGTTCCACTCATCCTTCGCCAAAGCAACAGTATTGCGGAAGTCCCAACCAGGAAGTTCCTTCTGCATATTCAATCGAGCGTTCTCAACACTCACAGCAGAGATACCTACCTTCACGAGAAGTGGCTGCTCAGCATTGTCGAAAGCAAAGACGCCAATCGTATCACGCTCGTTTGACTCCAACTTAACAGGCTGTGAGAACTCTGCCACGAAGTAAACGCGCTGGTCTTTAGCCCATCCTTGTGACATACGGTAGCCACTGACGGTCTTAGCCGACTCCTGCTTAAAGCTGCAAGAGGTCATCTTGTCCCAACCGATACCCTGTGAGAGGTTCAAAATAACGTAACCCTTTGTTGCATCAGCAGGGAAAGCGTAACGATGGAAGGCTACACGCTGGGTGGCAGTCAACTCTACACGAACACCAGAAGCCAACATTACAGAATAGTAACCTGGGGTTACATGCTCGGCACGATGGGCAAACTTCACCTCACGCTGTGCTGGATTGGTAGTAGGGAGGAGTGATACATCACCCAAGTCACCAATACCCGTACCGCTAAGGTGCATCTGTCCGAATCCGATAACTGTTGAATCGCTGTAATGATAACCAGAACACCAGTCCCAGCCCTGCTTCTTCTGTGTAGGACCAGCCTGAATGTTACCGAATGGAACATTAGCTCCAAGGAACACATGTCCGTGTCCGCCTGTTCCAATAAATGGGTCAACATACTGCGTATAGTCCTGCGCAAAAGCGAAAAGACTGGTTGCAGCAAACGCCATTAAAGTTAAGAACCTTTTTTTCATATATTGAATTGTTTTAATCTTCTTGTCTTATATGTCTTGACAGAGCCGTCATTCAACAGCTCATCAAGTGTTCGTTTACTTCTGATTGACGATGATTTCATCTGTGAAAATCCATGCGCCTTTCTCGCGAGGGAGTGCCTTCACACGGACATAACGACCTTTGACATCTCCTTTCCACTTGTAAGGATAGACGAGATAGTCCTCTGAAGCCTTAATACCGGGGCGTACTGTGTCAATCGTCTTGAAGTTCTTACCATCCTCTGACACCATCAACTCGATTGTCTCTGGCGTATAGATAACCGATTCATAGAGGTGCATAAAGTCAACACGAACGTCACGTATGTCCGTAACTCTACCCATATCAACTACTACATCCACACCAGTACTGTCGATGAAGCCCTGCCAACGGCCCTCAAGATAGCCCCAGTCACCACGCAAACCATTGGTCAGTGTGTTATCACCTTCGGCACGATACTTCTCTGCATATCGTCCTAAGTAAGTGACAGGCTTACCCAATGCCTCATGCTGTGTCACACTACGGCTTTCGATACGTGAGCCCTTTTCCTTTGAAAGGTCAAAGGCATTATAGCCCGCACGCTTCAGTCGGTCTACATTTACGACTGCTCTCTTGCGGAAGTTGTCGTAACCGGTGCGCTTCTTTGTCCAACCTGTCTCTGCCAAAGCAAACAAACGAGGATAGAGCATATACTCTAAATGGCTTGGCTCAGCGATGAACTCGGTCCATACACACGCCTGAACACCATCCATATATTTCTCAAGATTGCTTCCTTTGTACTCTGCAGGGATTGGCTCATAGTTGTAAGTCTTATCCAAACGAGTATATCCGCCCTGTGCCTTTGGCTGTTCCATCGGATTGTCCTGATACATATTCAGATAATAGAACTGCTGTGGTGCCATCACTACATGGTGCTTACTTGTTGCAGCCTCAATACCTGCTTCGGTTCCACGCCATGACATCACGGCTGCGTTAGGAGCCAACTTACCTTCCATAATCTCATCCCAACCGAGGAGTTTACGACCATTACGGTTCAAGAATTCTTCCATACGATGGGTGAAATGGCTCTGCAACTCGGCTACATCTTTTAAGTGATTCTCCTTCATCACCTTCTGACAATCAGGACAAGTCTTCCATGTGCGGCGCTCTGCCTCGTCTCCTCCGATGTGGATATACTTAGAAGGGAAGAGTTGCATTACCTCTTTCAACACGTTCTCCATGAAGCTATAGGTGGCTTCCTTACCTACACAGAGGTCTGACTGTGTATAAGGTTTACCTGTACATGACAACTCTGGGTAGGCATAAACAACCTCATCACTATGACCAGGCATCTCTATCTCTGGGATTACCTCAATGTGGCGCGCAGCTGCATAGCGTACGATATCCTTGATATCTTCCTGTGTGTAATAGCCACCGTATGCTCCCTGCGTATTCTTATGACAATACTTGCGGTCGTTATCCATCCACCACTTTGTCCAATCAGACTGTGTGCGATAAGAGGCTTCATCGGTCAAACGAGGATATTTCTTCACCTCCATGCGCCATCCACCACCATCGGTGAGGTGCCAGTGGAAGCGGTCGAGTTTGAAATAAGCCATCGCATCAATCTGCTTCTTCAAGAAGTCCTTTGTCCAAAAGTGTCGAGAGCAATCGATCATCAAACCACGATAAGCGAAACGAGGGGCGTCCTTCACCTTTACACAAGCTATCTGGCCATCCTTTTCGAGCTGGCGAACGGTTTGCAAACCATAGAACAAGCCTGTTGGAGTCAGTGCCTGAATAGTGATACCCTTTGGTGTTACCTCCAATTCATAGCCTTGCAGACGTACGCTGTCCATAGCCTGTGCTGCCTGCTGGGCTGTTCCCTTACAAATCAAGCGGAAAATACCCTGCTTAGAAGGATTCTTTGCGTATGCTAATGGATGCTTCAGCACCTCAGAAGTGTACTGATTCAACACCTTAAAATCACTACCTGTAAGATTGGTCACAATCTTTGTACCCTTATTCAGCTTGAATTGACCCTTCAAAAGGCTGATATTCTCAGGTTGTGGGATGATGTTCTGAGCTGCAACAGGCATAGAAACAGCTGCTGCAAACAACAGGAAAACTGCACTCAAAAGAACTTTTTTTCTCATAACGTGAGTATAAATGTCGATTTTATTTTTTTATTATTTGTTTTTACTTAATATCTCTTTCTTCGATGGCTGTAGGCTGTCTATCTTCTTATCTGCGGTCGTTTAATACCTTCCTGATAGTAGACTGCCTTTCAAATTGCCACCTTCTTGTTTCGTGTTAAGCCTCCGCACCAAATGTGCTAAGGCTCCGCACAACTCGTGCTAAGCCTCCGCACAACTTGTCCGAAGCGTTCGGACAAGGATAGAAGACGGCAAACAATGTCTGTTTTTATCATTACATATAATGTAATAAGACATTAAAGACCGTCGGAAGCGTGGGAGGTTTGATGGGTAGTAGTCGTTTACTTTAGATAGAACTTCAATACGCCACCCTTCAAGAGTTCGTCATTCGTAATGCGATAGCGGTTCAAAGGCTTACCACCTAACTCTATCTTCTTAATAATTACAGCCTCGTCATTTGGACGAACCGTCTCTATCACGAGGTTATCTCTGCCCCACTGTGCCTTATCCAAACGGATAGTCACCTTGTCAAAGACTGGCGAGGTGAGCGTGTAAGATGGATCACCCGGACAGTCAGGATAGAAACCTATCATATTAAATACCGCCCAAGCCGACATGGTTCCAGTGTCATCATTACCCGGGATGCCCTCTGGTGCGTTCTTGAAATACTCCTTCAAGAGTCTGCGTGTCTGCACCTGTGTACGCCACTCATCGCCCTTGAAATAAGAGAAGAGGTAAGGATAAGCGATATCAGGCTCATTGGCAGGGTCGTAATAACCCTTGTCGAACACGCTCTGAAGCTTGTTTACAAAGTTTTTCTGTCCTCCCATGAGCTTTGCAAGTCCCATGACATCATGCGGAACATAGAAAGTATAGTTCCAAGCATTGCCTTCATGGAAGCCCGGAGATGGTTCAAAGTTCTCGCCTTGCTTAGGATCGAAAGGCTTATAGAAGGTGCCGTCTGGCATCAATGGGCACAACAAGCCAAACTCCTTACTGAAGTAATGGCGATAACCCAAAGCACGGTTGTGGAACAGGCGGGCATCGTCTTTCTTACCCAATGCCGTAGCCAAACGTGAGAGGGCATTATCGGCAATATAGTATTCGAGTGCGTGAGAAACGGAATTGTCGAACTGCTCGTGCAAAGCTACATATCCCTTCTCCATATATTCGTCATTATCTGGGCGCAGAGGGTTCTCACTTCCCTTTGTCAAAGCCGACTTGCGGAACGCCTCGTAAGCCTTATTGATATCGTAACCACGCAGACCTTTCAACCAAGAATCAGTGATAACAGGGATAGCTGGGTCACCTTCCATCGTGTAGGTTTCACGACTAAAGAGTTCCCACTTTGGCATCCAGCCATGCTCCTCGTACATCCCAATCATCGAACGAATCATATCACGCTGACGATTTGGATAAACCAACGTAAGTAACTGATGCACATTGCGATAGGTATCCCACAGAGAGAAGACCGTATAACGATTGCCCTCCTTCACCGTGCGAATCTCATCACCCTCCATGGCAGGGTACTGTCCGTTGACATCCTGCAGGATATTTGGGTGGATAAGAACGTGATAAAGAGCTGTATAGAAGATGGTGCGCTCTGTCTTTGTACCACCCTCAACGAGGATGCGAGAGAGATCATCATTCCACTTAGCACGCGCCTCAGCACGAATGGCGTCGAAGTTCTTTCCACGCTGTTCGGCATCAAGGTTCTCACGAGCGTTTGCCATACTTACGAATGACACACCCATCTGCACCTCTACCTGCTCATCAGCCTCTGTGTTGAAGTTCATCCATACACCAATATCATCACCAGAGAGTTCCTTGTGATAGGTCTTATAAAGCTTATACTTGCCATTGTCGACATCCCACTCAGCCTCTACGCCTGTCATCGGACGCTGTTTCTTCCAATAGCCAGCCTCTGTAGGCTTCTTGCTGACACGCATCACGAAGTAAATTGGGAATACAGCCTGTGGGTTATAACAGAATGTACCCTGCAGTTTCATACCCTCATACTCCGTATCGCTCACCTTCTTCACCATGGCACCAGACTCATTTGTGAGTCCTTCACCGAGGTTCAGCAAGATATGACTTTCTCCTTTCGGGAATGTGAAACGTGCAACAGAACTGCGAGGAGTAGCTGTTACCTCTGTCTTCACATTATACTTTTTCAGATAATTAGAATAATAACCTGGGTGTGCAACCTCCTTTTCGTATGTACTTCCGTACTCCTTATAGTCTACATTCAGCTTTCCTGTCGTTGGCATAAGCAACAATGAGCCTACCTCTGGACAGCCCACACCACTCAAGTTGACGTGAGAATAACCAGTAAAAAAGACATTATGATATTCGTAAGGAGTTGACCACCAGCGTGCATCCTTGTCATATTTATTCAAATCGGAACCCATTACGTTGAATGGTACGACTGACATCAGTCCGTTAGGGCATACTGCTCCCGGATTGGTTGTACCAAAATTAGATGTTCCGATAAAAGGATTGACAAGGTCAACAGGCTCTTCCCCACCCTTACCAACCGCCTTCAGCGAGAGGAAAGACAAGGAAAGAAGTAGTACTAATAGGAATTTATGATTCATTTGGGTGGTGGATGTTGGATGTTAGGTGGTGATGAATAGTGGGTGATAGGTAGTGGGTGTTAGGTGGTGATGGGTGTTAGGTGGTGGATGGTGGGTGGTGATGAATTGTGATGAAGCTATCATTATTTACTTCTAAGCAATTCATCAACACTCAACACCTATCACCTATCACCTAACAATTCATCAACACCCAACACCCAACACTTAACACCTTATAATATACTATTGTTCTTTGTGAACTCTACGATGTCCTTGATATAGCCAAATGCCATACCAACGACGGTATCAGCTGCGCCATAGTAAACGGCTACACGCTCACCATCCTGCAAAGCAGCACATGGGAAGACAACGTTTGGCACGTCACCCTGCAACTCGTAAGGTGCATTTGGTGCAAGAAGATAAGGACGAGTACGATAGAGAACCTTCTCTGGATTGTCCTTATCAAGGATAGCTGCACCCATTGAATAACGGAAACCATTACAAGTAGTGATTACACCGTGATAGAAGAGCAACCAACCTTCGTCTGTCAAGAAAGGAACCGAACCTGCACCAATCTTTGTACACTGCCATGCACTCTCTGGGAATGGAGTCACCTTCATTACGCAACGATGCTCGCCCCAGTACTTCATGTCAGGGCTAAAGCTGATATAGATGTCACCAAAAGGAGTGTGACCATTGTCACTTGGACGGCTCAACATCGCATACTTTCCATTAATCTTCTCTGGGAAGAGTACGCCATTACGATTGAATGGCAAGAAAGCATTCTCACACTGATAGAACTTCTTGAAGTCGAAGGTGTAAGCAATACCGATTGTTGGTCCGTGATAACCGTTACACCAAGTAATCCAATAACGATCCTCAATCCATGTAACACGTGGGTCGTACTTGTATTCTGACTCAATCATCTCAGTGTTACCAGCCTCAAACTTGATAGGCTCATGATTGATTTCCCAGTTCACACCATCCTTACTGAAACCAGCAAAAATGTTCATCTGCACCGCCTTGTTATCGCAACGGAACACACCAGCGAAGCCATCCTCAAAAGGAACAACAGCACTATTGAAGATACTGTTTGATGTTGGAATATGATAACGATCGATGATTGGGTTCTTTGAATAACGCCACATCACATCCTTGCATCCTTCTGGACGGTCCTCCCAAGGCAGAATATCTTTTAAACTTTTCATTGTAAATATAGTTTTATGCTTTTAGTTTTTATAAATGTCTATACATTATAAGTACAAGCAAAGTTAGCTTTTTACTTCAACAAAAGGTAAGTTTTTACCATTCATTAAATAGGAAAAACACTTCTTAACAAGTGATGTTAAGAATCTGTTATTTAACCAAACAAACATACTAAGAAAATAGCCGTAATTACCGTTTAACCCAGTTCTGCACTTCCAATCCTTCTATACGTGCAAGGTGTTTTACATTCTCTGTTGCCACTGGAATCCCCAACGTAAGTGCCGTAGAGGCAATATAAAGGTCATTATCTTCTATCATTTGTCCCTTTCTTCGCAATACAGCTTTCTGACGACAGAACTCTTCGATACAAACAGAGAAAGGGATTATCTTAAGTTGGTTGAGCAAGTCTTTCAAAAGAGTACGGTTCTTTTCTGGATATGCACTACATTCTGCTCCATAAAGCAACTCAACAATAGAAATCTCAGACACACAACAGTTGCGCCACCCTGTTTCCAAGATGTGTTGCCGTACACTTTCATTCTTACGTAAGAGATGAATTAGAACATTGCTATCAAGCAAAACCTGACCATGTTGGCTCTTACTTTTCATACGCCTTCAAAGCTAATTGGTTCACTTGAACTGGAATTCTGCTTGATGATACCCATCAATTCTTCAGCAGTTTCGTTTCCTTCCCACTTCCCAAAAAACTTATTAAGCATTTCTTCTGTATAGGCTTCGTCAGACATTTCCTTACGTTCTTCCTCGAGTACAGAGTTAGTAAGTTTCACAGCTAAGCCCAACCGAATGTTCTTACTCATCGAACGCAATGCGTTCCAATACATACGTATCGTATTGTTCTCGATGTTTGTCATTATGCCCGCCATAATTATACCTCCTGTTTATATTTTTCTGCAAAAATAATGCAAACGAGAGCAAAGAAAGCTTGCTTTCAATTTGCCGAGTGCAGCTTATTTTCTGCAAATATAACGTTTTCCTATGACAACTCCAAATCTACATCTTGGTTTTCACTTTCTTATTGTAAGTGATTAGGTGAAAAGAGTCTTACACTATTACGCTCACAGCATAAGAGAATAACAGACCTAAATCTAACAATACTTTTATTTCTGTTTGCTGTCATTTTAACATTTAGACAGAAACCCTTGTAAACTAACCTATTACATCTTCATTCAGAGTGACAGAAGTGACAGGAAAATTATTTTTAGCTTAATATTGGCATCTTATTCCATCTTTGAAAACTCTGAGGAGGCAGATAGATTTCTCATATAATATGTACTGATTTTTAAATTCCTTATACGCTGGCAACGATAACCGCACATGAAAAGAAAAATAGTTCTTCCGTTAAATACGTAGACAGGTTAATAGAATGAGTTTAATCCACATACATGATATGATTAGCCTTAATTAAATGGTTTGATAAAGTGGGATAAACTACATGACAACTGTAATTAGGTGTGATGTTTATCTGGCTTCTACAAGCAACTTGTTCCCTTATTAATTGACGTTTGTAAACTATTTTCATGCAATTCAAAACCAAGACATGCTCTTTTGGCTTCTAAAAGACGCCTAATTGACTTGCTATAGGTGCCCTTTTGAAGTCTAACTAACGACCTTTTGAAGTCCAATTAAGCATCTTTTACCTTACCACTTTATAACTAATTGATTTTCTTATGGTTACAAACTTGATTCATATATATATTTTTACCGTTGGTTATAGATATTTTCTTTGAGATTATGTAATGGTTTTTCAAATCCTTATCTGCATATTTTCGAAGTATAAAAAAAATGATTTTCAATATCAGAGGATAATAATAGGATAGATAGTTGACAATCTTAGCAATTTTTTTTGTTTAGCGAGTAACTTTGGTTCTTTCACTAAAGCAATACGAAAAGCGTCCACACATTTAGCAGAAGAACCAAAAATAATTTAAACTTAAAGGGAAATTCACTTGCTTTTTACAAAAAGATTTCGTAAAATTGTACTCGTTTTTGATTTACCTAATAGATAATATAACTATGAATTCGAAGATTAAACTACTACTCATTGCGCTAACCTTGTCGTTATCTGCAAATGCACAGGAAATGAAGGAACAGGATGTTTTTAAGCATACAGCAATCGACACAACGCAGTTGATTGTTTCTTATGACCTAACCGTTAAATATGACCTATCAGGACAGAATAATCCTGACAATGAAAAGGTATATACTTACATCGGACGTAAGGTTTGCCAGAGCTTCGTGGAGAGTGAGCATAATGCCGACCTGCGCATGGCTAAAGCCTTTCTACGTAATGGGAAGCGAGGCTCAAGAGCATCTATGAAACTCGTGGCTAATGTTGGTGAAACCTTTATTGGCTATCCAAAGGGAAAGACAACAGTTATTTACAATATGGACGGAGCGGGCTCTTACCTTTATCAAGAGACTACTCCGAAGATGCAATGGAAGCTTACAACCGAGCATAAAATGCTTTTAGACTACGATTGTACAGCCGCAACCTGTTCTTATCGTGGAAGAAATTATAAGGTATGGTTCACCACCAAGATTCCGCTTTCCTATGGTCCGTGGAAGTTTACAGGACTGCCTGGCTTGGTTATGGAGGCTGAAACCAAAGAGGGAGATTATCACTGGACGGTTACTGGCATAGAAAAGCCTAAGACAGCAACGCCTATCTATTTCCTTGACAGGAACTATGTAAAGACTTCTCGTGAGAACACACGAAAGCAAGAGAGGCTTTTGCTGAAAGATCCTGCAGGCTACCTTGAGAGTTATGGCTACAACTTCACTACGACTAATTTCAATGGACAAGTTGTGAAACTAACGCTCTTTACATTCGACAATCCTTTGGAACGAGAATGATAAGACGCCTACTTATCTTACTATCGTTTATCGGCTTATTGTCTATAAACAGTATGGCTCAGAACAGTCAGGGAGACTCTCTGACTATTACTGGGCGTGTGGTTGATAATAAACATCAACCTATGGATGGCTGTATTCTTATAATCATACAAGAAAAGGATTCTTCCATTCTTGCCAGTAGCGTGACCAATGAAGACGGCAGATACGCTATCAGCTACCCACGAACAAATGACAATCTTCTTTTAAGCCTGACTGGATTCAATATAAAACGGCAGATAAAGCGGATAACTCCAACGAGTCAGACCGTTAACTTCAACACCACCTACGAGAGTATAACACTGAAAGAAGTGGAGATAAAGGCAAGAAAGCTATGGGGAAGTAGGGACACACTGAACTACTTGGTCTCTGCCTATATGAAAGGACAGGACAGAACCATCGGTGATATTCTCAAACAGCTGCCAGGTATCACATTAGAAGGTGGCATGGTGAAGTATCAAGGTGTACCTATCAACCATTTCTACATTGAGAACATGGATATGTTTGCGGGCAAGTATAGCATCGCAACGAATGGTATTAAGGCTGAAGATGTCAGTACGGTGCAGGTGATGGAAAACCATGAACACATCAAGGCATTGCAGGATCAGATACCACCTGAATCGGCAGCTATCAACTTAAGGCTAAAGAAGAAGGCAAAGGGCAGATGGCTAAAGACCATAGACTTAGGGGTAGGCTTCGATTCTAACGGCTTATTGAGAGAGGTCAATGCTGCCCTTATGTACTTTGCGCAAAGACAACAGCACGTTTTCTATTACGAAACAGATAATAACGGTTCAAGCGTCGATTGGTTTAAATCATACTATGGTGGGAGTAATATCGGAGTTTCTCGCCTTACATCCATCATCTTTCCGGGGTCGTCTCCTATAGGTAAGAGTCTACGTAACAATCAGCATAACCTATGTTTCAGTAATCTCAACAAACTAAGCGAAACGGCGGAAATAAAGTATAACATAACTTACAGGCACGATATCCAACGTCAAAGTAGCTATTCGCAAACCACTTATCTGCTCCCCGATGCAAGTACTCGTTTGATGACCGAAGACATTTCTGCACGTAATACGACGAACGCTGCCACAATGCAGTTGCATTTTGAGAACAACGGCAGTAAGACTTATCTTAAAAACACACTTGACTTAGCAGGAAACTGGAGCGACGACAATGGACTGGCTTTGTCAAACAATGCACGTATTCAGCAACATGCCTTTAACAGAAACTTAGGACTGAACAATCACACGGAGTGGATTCAGCGTACAACCAATGGTGGAGGTTTTAAGCTAAAGACAACCAACTTTGTACAGACAAATCCACAAGCTCTCACCATTGAAGGGGATATGCAGGTAAGACAAGATGCGAGACTCTCAAACATGGGAAGTTACAACAGTCTCACTTTGATAAGAAACATCCGAAAACACAACTGGTCCCTTGCGCCTTCCGCAGAACTGAATATTGAATATGTGGGACTGAAAAGTTTATTAAACGATACAGCTGTGACGATGGCGACGAGCGGAGACATGGGTTACTTGCAGATGAAAAGCAACTTGGGAGCCAACCTACAATATGTCAAAAATACGTTCCGTCTATCGTTCAATCTGCCTTTATCTTTTAACTACACAAAGGTAGATAACGAACCAATAGCTAACGAGACGACGAAAGGAAAGCGCACAACCCTACTCTTCTCGCCATCTTTTACAATGCTTTGGAAAGCAACGGACAATTGGACGCTTTCTGCAGGAGGAAGTTATGGAATGTTTCCTACGAGTTGGAGAAGTCTGTTCACTGCTTATCTGATGAGCAACTATAGGACACTGAACCGCTACAAGATGAATCTATCGGAAAACAAATCGGCATCTATACATGGGAAGATACACTACAAGAATATCCCGCATCAATTCTTTGCCTATCTCTCTGGGGCGGTTAGTCGCTCATGGAGTGACATGATTTATGGTACGACAATAGACCAAAATGCGCATACATTGCTGCAAGCTGAATATGCTCCGAACCACCAAAACAACTTCTCTATGACGGCAAATGTACGAAAGGAGATTGCTTGGCACGACATGAGTATCGGGGCAACAGCTGATTATTCGACTAACACAAGCAAGATACTCCGCCAGTCTGTCATCACCGACTATCAGTATAATAGTTTCATCATCTCTGCTAATCTTACCTTTAATCTTTTAAAGAATACCCGACTAACAGAGAACTGTCGATGGGCAATCTCTCAATCAAAGTCGGGTAACTACAAGAATATTATTCGCAACTTTAGCAATGAGGTTGCGCTCTCCATGGCTTTTATCCCTGACAGACTGATACTTAACACTAACCTACAATACACGCATAACAGTGGTTTTACGGATAAAAAGGATTACACCTTTATGAATCTTAGTATCACCTTTAAAACAAAAAAGAAGATACAATTCGTTCTTAACTTCGATAATATCTTCAATACAAAAACCTTTATCTATCGTTCTAACAGCAATCTTTCCGAAAGCTACACCCTCTACCAGCTTCGTCCAAGAAGTGTGATGCTCACTACCCACTTTGCTTTATAACAGAAAAAGCAATCGTGTCCGTCCCTATCTTGACAAGAATGAGAGCATACGATCAACCTCGAATATTGATTTTTCTCTATTAAATCGCCCTACTTATTTCCTAATATTATATCCAAAAAGGGATATATCTCTGCTTCGTTCTCGTATGGATAAACCTTAAAATAGGCGTTGCCATTCAGCATAGCGGAGATATTGGCTTTGCGCTTGTCATAGAAGATATGGACAGGGATATTACGAGCCTCAGCGTATGCTAATTCATAACCAACGCCATGAGAGGGGTTCGTACATTCTGCTATCAGCACATCGGATGACCTAAGCCATTCTGTATCACGCTCATAAATATGCACATCATCTTCTTTTGTTCTCGCTTTTACGTTCAAACTTCCTAAACCGATATGCTCCGTCAACACTGTATCAGTCCTGTTGATATAGTCTATAATCCGCTTATACACAGCCGCATCCTCCCTACCACCACGGATAGAACCTGCAAAATAAACCTTCTTCTCCATAAAACAATGCTTTCGTTGATAAAACATACTTGAGTAATACTCGCCCACAAAGATAACACTTTATAGTGAGAAACAGATGACTTAGATAGCTAATAAACTTTCTTTCTATCCTTCTAACGATACAAAAAGGCTATCCTTTTGCAAGCTATAAAAGGCGGAGTGTTGAACGAAAAATGTTTACATAAAATCTTGTAAAACACCTAAAACAAAGGTAGAAAACACGTATAAGGAGGAGGTCTGCAACAGTCAGGAATTCAATTAGTTACAAAGACGATACCAAAAAGGTGCTTAATTGGACTCCAAAAGGGCGTTAGTAAGGGGCTTAAAGGGCATCTTTTGCAAACCAAAAGGGCGTTAATTGAAAGGTAATTTACGCCCTTGCGATTTTCGATGTTAGAATTATCTTTACAAGACAGAATGACATAATGAACAAATAATGACAGAATAATTAAAAGAGACAGAAGGATGGAAGAAGACAGAATGACAAAATGAACAAAAAGGACAAAAGAGACAGAATGACAAAAAAGACAGAATAATAAGAAAACGGAAGGACAGAAACAGAAGGGCAGAAGGAGATTTATTATGTATACATGATTTTATTATAATTGAGAATTGATTGTAATGTAGAGATTTATTCTAATTATGCAACAAGTTGTTGCATGATTGACCTTAATACTAATGTTAGCTATGAAATAAGAGAATCAATGGTTTTAACTACTTCTAATCTTCTTTCATTTTTGCATATTTCAATTTTGCTGTCACTGCTATCACTTAAAGGCACAAGCTAACTCGTTAGATTACAGAGGGAATGATTGAAATGTTAAAAGTGACAGCAAATCAAAACAAAACTTATATTGTGAGAAGTGTAATAGTTTCTCTTGTTAGAAAATAGTTATCACTCCCTATATAGGAAGAAGCGAATATAAACACACGCATCCGATATTTATACAGATTACTTTTGGCAGTTTGATAAGAAAGTATTACTTTTGCATCGGTTTTCAAAATGGAAACTAAGGGGTGCTTGCCTGTTTGGGCTTGCTGAGATTATACCCATTGACCTGATACGGATAATGCCGTCGTAGGAAGATTTCCCCTTATACTTTTTTCTTAAATCATCAATCTGGGATATGAAAAGAATTATCCTGTTTACTGCTGCACTGACGTGCGTGGCAGCTATAAAGGCGCAAACAGTGACGGACACGCTGAGACAACAGCAGCTTGACGAGGTCGTTGTGGCAGGTGTACGTGCGCCAAAGAGTGCTCCATACGCTGTTTCTAATATCAAAAAAACGGAACTTGAGGCATTCTCTAAGAGTGGACGTGAGTTACCATTCCTCCTCTCACAGACGCCGGGCGTATTGGCTTGGGGCGAGAATGGACTTGGAACGGGTACGGCAGCTATGCGCATTCGTGGTGCTGCGGGCAGTAGAATCAACATCACCTTAGACGGTGTTGCACTTAATTCGCCTGAGGATCAGACGGTGTTTTGGGCAAATATGAACTCTTACGCATCGCTGATGAATAGTGTACAGATACAGCGTGGTATCGGTACATCAACCAATGGTGACGGTGCTTTCGGTGGTTCGGTGTCGTTGGCAACGAGTGCACCAAGCACGAAGCCGAGTGTTGAGGTGAGTGGCTCATACGGCTCATACAATACGTATAACGCAGGTGTGAAGTTCTCTACAGGTCTGCTCTTTAATCATCTTGTCTTCGATGGAGCCTATCATGAGACCGCAACAGACGGATATGTTCACGGAACAAGTGGGCGTTCGGGTTCTTATTATGGTGGTCTTACATGGTTGGGGGATAACTTCCGCATCAGCTATAAGAACATCGGTAACTTTGAAAAGACTGGACAAGCATGGAACGGTGTCGTTACGGGTAGTAATGACTTGAGTCTGATGGATGGTACCTACGGTGCTAAGACTGGCATCACAACCTATAAAGATATGTATGAAAGGGGATTAGGTAAGTTCAACCAACTCTATGAATACTTGCAGACTGATGCTAACGGAGCCTTCGTTAAGGATGCAAACGGCAACTACCAGACAGCACGTTACACGATGCGTGACGGCTCTTTCTGGAACAAAACAACAGATAATTTCTATCAAAATCATAACCTCTTGTCGTTTGCTTTCCACCCTTCCAATCATTGGAGTCATAACGTAACCCTGAATTACACCTATGGTTACGGCTATTACAGTGAATTTAAGCATAACACAAAGTTTGAGAAGTTCGGTTTGGCATTCACCGATAGCAAGGGTAAGTTTATCAAGAAATCTGACTTCGTACGCTTGAAAGGTTTGTCACAGCACACCTACGGCATTGTTTACACCAGCAATTACAAGGACGAGAGTTGGGATGTGACAGGCGGACTGAACCTGCAGCAGTTCCGTGGCAGTCACTTCGGCTACCTTACTTATATAAAGAATGAGGAGGCAGATGCGAAGTATCGTGCTGGTGGCAATGATTATAAGTATTATGACTCTAAGGCACATAAGTATGATTACAGCGGATTCTTCAAGGCAAAATACAACTTTGCAGACTATTGGAATGTATTTATGGACCTGCAGATCCGTCATGTGGAGTATATGACCGATGGTCAGAACGACCGTTTCTATAAGGTCGGCAGTGGCTATCAGAACCAGCTCTTAGACGTCAACGAGCGCTATGACTTCGTTAATCCGAAAGCAGGAATCAGCTATTATCGTGGTGGTCACAAGGCTTATGCATCTATTGCGCATGCCAGTCGTGAGCCAGAACGTAATAACTTCACCAACAACGGTAGTTATCCTGCACCATCGCCAGAGCGTATGGTGGATATCGAAATGGGCTATCAATACAATGGTCGCAATTGGAGAGCAGGGGTGAACCTCTATTATATGAACTATAACAACCAGTTTGTACAGACTGGTGCGCAGAGTGATATCGGTGCGAACCTGACAACGAACATCAAGGACAGCTATCGTATGGGAGCTGAGTTGGAGGCAGGATGGAGCCCATTGTCATGGTTGACCGTTGAGGGTAACGCTGCTTTGAGCCGTAATATCATCAAGGACTTTGACGAGATGGCAAGTGTAGATTGGGAGGCTTCTTTCCGTAAGATTCATTACAACCACTCCACTTTGGCATTCTCACCATCAGCTATCCTCAATGGTATGCTCAATCTCCATTATAAAGGTTTTGAGGCTGTGTGGCATACAAACTTCGTCAGTCGTCAATATCTCGACAATACCGAGAATATGACACGTTCGTTGCCATGCTATTCACAGACGAATATCAACCTCAGCTATACCCTTCGTCCAAGCAAACACATTGCAGGTTTGAAGGAAGCTGTCTTCGGTGTGAACCTCAACAACATCTTCAATCGCCATTATGCTGCCAGCGGATGGGTGTATAGTTCCATCCTCGACCACGACGGTCATCCTAACGAGAACCGTTACACGCAGATTGGTTTTATCCCAATGGCAGGGTTTAATGTGATGGGAAGTGTTGCGTTGAAGTTTTAAACAGAAAGCAGCGACCAAGCAACACCAACTGGCCCCTCCCCCAAAGGGAGGGGCGTGAAATGTACTGTTTGCTTGTAGATTGCTTATAAGAAAAGGGTCAACTCCCAAGCAGGACAACTGGTCTACACGCAAGCTTATCTACTTGTAAACTTATGCAATAAATACAAGGGAAATACACTGTATGCTTTGCAAGAAGAGCCAACTTCCAAGCAGGACAAATTGTTTACACGCAAGCTTGTCTACTTGTAAACTCATCTACTAATCACAAGGGGTATCACACATTCTACGCCCCTCCCTTTGGGGGAGGGGATGGGGGAGGGGCCACTTGGTGGTGCTACGCTATCTTATTTTAAATTATGACATTAGACATGCTGGGCTGCATCGTCGGCCTAATTTACATCTATCAAGAATACAAAGCGAGTATATGGCTTTGGTTGACGGGGATTATTATGCCTGTCATCTATATGTTTGTCTATTACGAGGCAGGACTGTATGCGGACTTTGGAATGCAGATATATTATACCTTAGCAGCCATCTATGGCTTTTTGTATTGGAAGTTCGGAAGGAAGAAAGGGGCGGAGGAGATTCCTATCACACACTATCCTCGACAGTTGATACTCCCTTCATTGGTTACCTTCCTCCTTCTCTGGGCTGCACTTTATATCATCCTCATCAAGTTCACGAACTCTACCGTACCGGTATTAGATAGCTTCGGCAATGCACTCAGCTTCATCGGACTGTGGGCGTTAGCAAAGAAATACATCGAACAGTGGTGGATATGGATTGTTGTCGATATCGAATTGGCAGGACTTTATGTATATAAAGAGATTCCTTTCACCGCAGGACTCTATGCCTTCTATGCCGTTATCGCTGTGGCTGGATATTTTAAGTGGAGGAGGAGCCTCCCCCAACCCCTCCGAAAGGAGGGGAGTGCAAATAGGGAAGACCTCCCCTAACTATTAGAAGAAAAAGATATCTATCGGGACAAAGACCTCCCCTAACCCCTCCAAAGGAGGGGGATGCCTAACGGGATAAAGGCTTCCCAAAGCTCCCCAAATTATATTGATAGGTTGAAGAATGAAGTTACAGCAATAAATAAAACAAATACAAAGTATCTCGAAAGGGAGAAAGATTAGAATAAGAATAGCAAGATAAATGATTATCAATAACAAAGAGAATAATAAGGACGGACAACAACAACACATTACCAACGAACACCCCGTTAGGCTTTCCCCTCCTTTGGAGGTGTTAGGGGAGGTCTCTTCGATTAGGCACTCCCCTCCTTTCGGAGGGGTTGGGGGAGGCTTTAGTGCCGTCATCCTTGCTGCTGGCGACTTCCCAACCCACGTCCTACCCCTTCACATCCTACGTACTGCGGAAAATCTGATTGTTTGTGATGGTGCTTTGGAGGATTTATTGGAATATGATATAGAGCCAACAGCAGTGGTGGGCGATGGCGACTCACTTTCAGAAGAGTTCAAACAACGCTATGCACACATCTATCATCCGATTTCGGAGCAAGAGTTTAACGACCTCACCAAGGCTACCCTCTTTGCTCGTTCACATCTAAAGATGGACGCATCTACACATACTCGTCCTCGCTTCTGCTATCTCGGAGCAACGGGAAAGCGTGAGGATCATACTTTGGGCAACATCTCTCTCATGCTCTATTACTATCGTCAGTTGGCTATCGACCCAGTGATGGTAACCGACTATGGATATTTTGTTGCAGCATCGGGTACAATGCGTTTTGAATCATTCCCTGGACAGCAAGTCAGTATCTTCAATACTACCTGCAAGGAGCTAAGTAGTAACGGACTGAAATGGGATATCTATCCATTCAGCGAGCTATGGCAGGGAACACTGAACGAAGCCTTATCGAATGAATTTACAATCCAAGCGGATGGTGATTACTTAATTTACCGTACGCATAAAATATAACAAACCTTTTCTACAAATCAAAATGCCATATCTTCATCTCCGTAGGGAGATGTCGATATGGCTTTATTTAGATTCTTCCGTTAAATGGCGTAGATTGTTAATAGAATAAAATCAATCCACAGACATGGAATGATTATCCCTAATTAGATGGTTTTACAAAGGGAGAGTAAACTACTTGATAAATGTAATTAGGTGTGATGTCTATCTGTCTTCTACAAACAACTAATTCCTACATAATTGATTTTTGTAAGCTATTTTCATACAGTTCAAACACAATACATGCTCTTTTAGCTTTTCTGAGTTTGTAGCAAGTCTCTTCCCCAAAAATAGCATATCAGCTTATTTTTGAAGAAGCTTTTATAGACGCTCACATCAAGTGTCCCTCCCGCTTTATAAATACTAACTGTACTTGCATATGGTGAGGTATAAGAGAAATTAACCCAAGTTTAACCGGCAAAATTATTTTTCATAAATTTTCGGGATGTTTTGTGTAGTATCAATTTGATAAATGATTGATAATCAAGTATAGGGTATTGTAACGAGGAGTAAAATCTGATTTGTAGGACACAGCCATATCAAAAATATTTTGTTACTTTGCACTCATGCACGCAAATGTACAGACACGAATCAACCCTGCCACAGGGGACATGGCTCCTTATTATCGCATCAAGGAGTCATATCGTGACGTGCAGGGTCATGTACATTCGCTAATTCTGTTGAACATCGGGTTCGAACCTTCACTTACTGCTGTACAGGTTCGAAAAATTGCATATGCTCTTACCGAACGCTTCAAAAACAGAAGTACACCCTCGCTTCTCAAAGAACACCTTGAGGGTCTTACTCCTATTGAACAGGCAAAGGCTGACGAATGGTGGATCCGTATGGAGAAAGAAGGTGGAATCGATCGGTTTAATAAGGAAGAGCAGAAGTCGCTGAGAAAATATGAGAACTACATAGACCTTGAGACGGCAAACTATACTGACGCAAGGAATGTTGGTGCAGAGTGGCTCTGCAAGCAGACGATAGACAAGCTGCAGTTAGAGGGTTTTCTGCGCAAAAACGGCTGGACGGAGAATGCAATACACACGGCTTTGTCAGCATTGATTGTTCGCACGGTATATGCTGTTTCTGAACGTTCATCTTATTATTATTTGCGCGATAACTCGGCTGCTGGCGAACTTTACAATGGAGTTCCTGACTGGACACCAGGAATCAATTCTCTGTATAATATCACTGACAAGTTATATGAACTAAAGGAACAGTTAGAGCGTCATTTGTGCAGCGTTACTGACGACCTCTTTAATATAGACAACAAGTTGATGCTCTTCGACTTAACCAACTTCTATTTCGAGGGTAGTAAGCGTAATAGCGATAAAGCCAAGTTCGGTCGTTCAAAAGAAAAACGCTCTGACTGTAAGCTACTTGTACTTGCATTATGTATCAATCAAGAAGGTTTTATACGTTATTCTTCTATCTTAGAGGGTAATACAGCAGATCCCAAGTCTCTACCCAATATGATTGATACGCTGGCAAAGAAGAATCCATCAAGAACAAAGGATACGCTTGTTGTCATGGATGCAGGTGTTGCCACGGAAGAGAACTTGGAGCTAATAAAGAAAAAGGGTTACAATTATCTCTGCGTATCCCGTACGAAAATGAAAGACTATACGCTCAGTGATGATAACAAGAGTGTTACGGTAATGGATGCCCGTCGGCAAAAGGTAACGCTGAAAGAGGTTAAGACAGAGGATGATAAGGATTATTATCTCGAAATAACATCTCCTTCGAAAGCTATGACAGAGTCATCCATGAACAGGGTTTGGAAAGAGCGTTTTGAGATGGAACTGCAGAGGATAAACGATGGAATCTCCAAGAAAGGTGGAACAAAAACCTATGAAAAGGTTGTTGAACGTACAGGACGTGCCATACAGAAGTACCCTTCTATAGCGAAGTTCTACCAGATAAGCTACATAAAAGATGAGAAGAAACTCAAGGAGATGCTGCGTGTAGACTGGGAGATAAAAGACCTCTCGGCAATGGAATCTGGTCACGGAGTCTATTTCCTCCGCAGCAATGTCAGGACACTTTCTGAGCGTGTGACATGGGAATACTACAATCTCATTCGTGAGATAGAATGCACGAACAGGCAACTAAAGAATGACCTCAACCTCCGTCCTATCTATCATCAGAAAGATGAGCGAAGCGACGCACACCTCTTCTTCGGTTTATTAGCCTACTGGGTGGTAAACACTATCCGTTGTCAATTAAAACGAGAAGGAGAATCCTGTTACTGGACCGAGATAGTACGACGTATGAGTACCCAAAAGCTCGTCACCACAAAAGGGAAGAATCCATTAGGTGAGAACACCGAGATGCGCCAATGTAGTAGTCCTTCAAAGCAAGCAAAACAGATATACGATAAGTTGAACTTAAAACACTCACCATTCAAAAAGAATAAAATTTGTAGGACACAGAGCCCATAAGAAAAACGAGGAAAGTACGGTGACAGTAACAATTAGGCGAAGGTGGGTATTAAACTTGGGTTAAACTTATGATTTCGTTAATTTATTTGGTTATTATAGGGCTTCCTTTGGCAAAATAAGTACATTTTATAATGCTTACGGTTTAAAACTGAAAACCAAGCCCATGGATAAGTAAAACGGCTGCAACACCGATGGATAAAGAGATACAGAGCTTTCAGTTTATTTTTATCGGACAGCAATATTTCTAAATCAATTGTACAACAAACAGCTGAAGTATCTTATACTGCCTCAACAGCAATTATATCCACCTTCGTAAACATATCGTTTATTATAGCGATCAAGTTTGAACTACTGGTAACCTAATTCCCAACTTATAGAAACGGACATAGCCAGAAACCTTTTCAAATGCTGGTTCTTCTGTCTTTGTAAAAGTAAATCGTTCTTCTTGATCTTGGTCTGGATAGATAATGAGACACTTAATAGGCAGTGCAGTTTCTTCATTCAAACCTAATTCTTTATAGATTTTGCTTAGTCGGGCATAACCACTCACTTCCCTTGCATCATCTATAGTTATACCACCACCCTGCTTATAACGTGGTTTATATTTCGCATCAATAACGTAAGGTTCAGTCCACTCTGTCGGTTTCAGGAGATAATCAAGTTCTTGATAATGAGCTTTCACATGATATTGAATCTCTCTTTTCCTTGTAAAAATCTTCTTAAGCTTACCAAAAACATATAACTCAAAGAGCTTACTCATATCAATCCAGAACGGAGGCGTGACTATCTGGCTTTTACCAACAAGTGTAATATCATAACTGAAACGCCTTAGCAGCAGTTGTGCATACTCAACAGCCGTGAAGTATTCTTTGAAAACAGGATTTCCCTTAAATGTCTTCATAGCCTTAACACTTATCTCATCGCCCACCCGCTCGAAAGAAGGCTGCACATATCTTATCTTCTTTTCCAAAGCCTTTGTATCAAGTGCATGCTTATAAACCTCCAACTGCTTCTTACAAAAAGCAAGTGCCTTCTTTAGTATTCTGTTCTCTGGTGAGTCAATGTCATACACCTGGTAACGGCAGACATTGTCTGTAATACGTCCCTTCGCAAGGTTTCGCTGAATCGTTCTACTGACAAGGATATGTCCTTTAACCTTATTGTTTAGGTTTTCTTCAACCCTATAGTAACTCTTCTTCAACCCCTTTCTTACGATACGCTGAAGAATATTCAGATACTCTGTAATCAAGAAGATACTCAACAAGTCTTGCTTCTGACTGATACAGATAGAAGGTTTATCAAAACGAATGGTGAGTAAGTCTTTCAGATGCTCCATGTTATCAGGTTCTGCTAATGCCTCGTTTAACATACGAACATAGTCTATCTCAAAGCCGTCATTCATCTTAGGACTGACTTGTACTGCTAACTCCTCTTCCTTAATCCAGTCTACCCCAACGAAATAAGAGCCAGTGGCACAGATGCTATCCGCTTTACGAGATAGCTTCAGACAGAGTTCCTTCTCCTCACGCCCTCTTTTAACCCCACGCACAACTTCCGAGCCATCATCCATATAAGGGATGATAGCTTCACACTCAGTCTGCTGGAGATAAGTATTCTCCAACAACTGTTCTTGAAGTTGCACTACTCTCATTACTCGGTTGCTTGCTTATATAGTTGGTCGATAATATCTTGTGCCTCTGCTGTCAGCACACCATCACGAACATACTCTTCTAAAAGTGGAATAATCTCATATAGAAGACGATCGGTTGTATTATCATTCCCTTCCTCATCCTACATCAGGAAGTAACTATGACCAATCCAAACATCTTCTGGCTTATATTCATCAGACAAGGTATCTGCTGATTCGAGTTTCATAGTCAGGTCCCAACCACTCTCCTTATAATCACCAAAGTTCTTAACAAACAGACTACTAACCTTCTCAAAAAGATCCTCATCGAACCCATCTACTTCTAAGCCAAATGGCTTCTCTGCTATGAAAGCAAAACGTCGTCTGATAGCATAATCAAGCGAGCCCAAAGAGCGGTCGGCAGTATTCATGGTTGCAATCAGATAGACATTGTTTGGAATATGAAAAGCTTTCTTAGAGTAAGGCAGCACCACACTTTCAGCATTAATACGTCCCTTACGCTTGTCTGCTTCAAGCAGTGTTATCAGCTCGCCAAACACCTTCGAGACATTTCCACGGTTCAACTCGTCAATAACCATCACATAGGCTTTGTCGTTCTCCTCCATCTTAGAGGAAGTATCGTACTTCTCAAGAATTGATTTTACATCATTAAGCGTAATAGAATTCAAACGGTAGACAGAAGACTCTACCATTGTCTTACCATCATTCATCTCTACAATGTTCTCATTGATATTCTTTACAAGCCAGTTAACACGTCTAACACGCTTATAGTTAGGGAACTTATCCTCAAACTCATAATCACTAACAACGACTCCAATGGCATCAATCGTCTGACTTGAATAACACGACATAACGATATCGCCAATCTTCATCTTATTGATGTAAGCATCTAATATCTTTCTACCCGTTTCATTATGAATAGTCCAGTCGGTTTCATCAGAAATAACAGGACCATAGCCGTCCCATCCAATACGTATATGGTTATTCTCCATACACTCACGACGAACATTATTATCTCCCGTTCCTGCAAGTGAAACCTTCCAGACAACAGCATTATCAGAGATACCCACCTTCTTATCCTTAACTACAGGGCGTTCTGCCTCTTCACACAACTTCTTGAAGATTCCGCTTTCTATCTCGTAGGTTACTTGACTATTCTCGTTGACAACAGGGCGCAATCCTTCAATCCAATCCTCATAGTCTAAGGACTGATGGAAGGTTGTAAAGGCAATACGCTTTTCCGTTTTAAGCTGATTGTATCTGCTTACTATCTCCTCCCTACTCGGTTCTGCAGCCATAAACGCAGAATCACAAAGACGAACAGCAAGCTCTGGTACGTCATAAGTCTTACCAGTACCCGGCGCACCATATAATACTATGTTCTTACGTCGCTCCCATATACGGACAACATCATCATACCATACCCCTTTTGAACTATTATTTGTCTCTGTAGTCATCTTATTTTTCAATTCCTCTTTCATGTAATCTTTCATACACCAGAATAAAGTCTGCACCGCAAGGTTGAGCGGTTTATTCTTAAATCCTTTGATTTCATTCAGCATTATCTGCTGTATTTCCTCTCCATAGCTCTTTACGAAACCATTGACAAGTTCCATAAAGTGCTCATATTTCTTTCCTGCCTTTCGAGAAGTATAACCGAAGTAATCACAAATATTCTTATATATTTCATCCTTATAGAAAGTATAAGTCTTTGGATAAACACAGGTAAGCAAGGCTGATGCTGTACGCTCATCATTTGCAGTGTTCTTCCATTTACTTGGACACAAAGCCTTTATCTCTGACTTAAAAGCTGCTAATCGTTCGTTTAATGGAACAGACTCGTCAATCAGATGTTGACAGCAAACTCTTGTCTTGTCGGCTTCATTCTCAACCAAATACTTTATAACAGAATCAGTGCGAGGATTATCTATAACATTCTCTCCTCTAAGACCATCGAAGACTGCAAGCACATCTTTCCCTTCCGACCTATCAAGTAAGTTCCATTTATATTCTTCTTTATAACCATTAAAAGGTTTTCCATTTCTGAAGACATCTATAAGCGTTTTCATCAAATAGATTCTAAGGGCTTCTACAAGCTCATCACGCAGCTGCCATTGGAACCCTTGCTTTGTGTCCCAACCTTTTTGCATCGTAATACACCAGTAAGTATCTTTATCGTCTGCGTCTTTTACGCTAAATCTATTCAAGCGTTTTTGTACCCACTTAGAGAAGTTATACACCTTACTGTTATAATGCTCAGCAGGCTTCCCATATACTTGGGAAACCTTTACACAAGTTGCCTTATGTTCTTTTTGACGTAGGAAACACAGCAAAGCTTCATGATATGGCATTGACTTCTCATCACGTAGTAAATCAAGCCATTCCTCCGTGGTGACACCTATATCACCACAGCTATATTCTCCGTTTGTATTTATCGTCTTATATAATGTCTTTACAGCCATAAACTTAGCAGTCTTCAGTTATAATGCGCTATTAATATCCTCACAACTTACTTTTATTTTCATTTGCTGTCATTTTAACATTTGCGTAGAGTTCATTGTAAATCAACAAGTTAAACACCCACAACCAATGACAGAAGTGACAGGAAAGTTTGTTTTGAAGTGCCGAACTACAAATATAACGACTTTGTTTGACATATCGTTATTTTATGTTTACAAATTTTATTTTATATATTTTCCGCAAGTTCACCATAGAACTGCAATCCCTCGCGTAGGTGTAGCTTAATCATCTATACTAAAAACCATCGAGGAGTTTGGGGGCGAGCAGCTGCCATTGGCACAAAACCATTTCTATACTCAAAAGCGAGTACAGAAATGGTCATTCTTAAAGACTTGTTTCAAACAGTATGATTATCAAAATGGAACTTACATTTTGACACACCGTCCTTATATTGTTCTTATCTCCTTCGAAGAGAATCTACAGAGAGTTCAAGCCCAGATATTGGTCTGTCACTCTGTATAATAGAAACTAACGAATCATTTTCAAATGTTAATGCCGTTGTTATAATGAATCCTTCACATTGGACACGAGCAGGTTCCTTATAATACAAAACGTCTATTCTCTTATGGTTTCTTGTAAAAACATCAGACCTAAATGGAAAACCACATTGTTTTTTCACATCTGCTTTATTGAGTCCTAAACGAATGTCTGACACCGGAAATTTAGACAATGTAGGTGCAATAGAACAAGAGTAAAGCCCTAAGATAGAGACGCAAAATGATAATATTATTTTATTTAGTTTCATTTTTATCACCTTTTATGTTTAAGCATTGTTCGACACTTGTTATTTTTCAGAAGAAATAACAAACTCATTCTCGTCATTAGAACATCCCCAAAACAGAACGTTGTACGCAGTACAAGGGATGAAAGTAAAAGGATTTTTTCATGTCAATAAAGGTTCAATAATTATTCGCCATAAAGGTACATTTATTTTTTGTATCTTTATTAAAAGCGATAAATAATTTTACTCAGTTTCCATTATCTTTTTCTTTAATGCCCGATTAGCAATTATAACAAACATCTTTTCTTTCCTGCTCACAGGGGTATCGCGCATTCTACTCCCCTCCCTTTTGGGGAGGGGCGGGGGTGGGGTGATTTTCCCTCCACCATTTCACAGCAGCATTCATAATCTCCTTCATGCCGTCGAAAATCTCATCGATATTACTTTGTTTTAATTCACCGTTGCCTTCTCCACCTGCATGCTTGAGAATAAAGGTTTTATCATGGGGAGAATAACCACAAAGAGAACGGCTTTTAATCACATTTAAATCGTCTTCAAAGCGGTCAGGCGTGGTATCAATCACCTGAACATTCAGACGAGGCCATGTAGAGCATTCAATCAACTTAAATAGTTTTCCGTCCACCTCGTGAACAGAATAATGGAAATCATAGGTTTTCATTGTGCAATTACTCATTTTGTTGGGTCTTCTGAAACTTGGAATCATAAGGCTGTCCGCCTAAATTTTGAACTCTGACGGAATGTCACACAGAGAAAAGGAGTGTACAGAGGCTTATTGCATACAAGGCAATGGAAGTCACAGAGGCACCGTCGGTGCGTGGAGAAACGAAGGTTATTTGCCAGTTTTATTAGAGATTTTATGCCCAAAGCATTTACCCCAAAACTTATCAGGAATCTGTACGCTTCATCTCCGTCGCTCATTGTGCCACTGGCACCTCCCTGACATTGCACTTAGCTCCGTCCTCTCCGTGGCTCTGTGTGCCTTATTATGTATGCACCTTACCTCATCAATCCATATTTCATAAGTACCATTTTACGCCAGTTCGGGATAAGGATTTGCTTAGAAAAGTTCCAATTGCCTAGTCTTTTCAATGCGCACGGGAAGTGCCTCGGGCTTATTCTCGAAGAAACAATATGTTGCCAATGCCGCACAGAGATTCATGAGAAAGTTATGTACGGAGCGATGGCGTGAATGGACAAGGTTGGCCTTGTTCTTGAGCAGTTCGTTGATGCATTCTATTATATATCGCTTGCGCAGCATCATCTTGTCCCACAAGGGCATAAGATTGTTTTTCATGTTTGATTTGAGCCCGTGAACGAGATGGATGCCTTGGTTGAAGAGGTTCTCAAAGAACTCTTGCTTGATGTAGCCCTTATCGGCAAATACTTTGCCGTAGAGCACCTTGGTGAAGACCTGCCACACCCTAGGGTCCCTGTCGTCCACGTTTGCGGGAGTTAGGCAGAACGTGAGTACATCGCCCATCTCGTAGCACAGCAGATGAAGCTTGAAGCCATGACACCACCCCATTGTTCCCTTTCCGTTCTTAGCAAGTCCATCAAACACCTTGTTGAAATTCCTTCTCATGTTGTGGCATACGGGAATCATCGTGCTGTCCACGAAACTAATGCCCGTGCACTTTCCAAAACCTTGGATGCGCATGAAGGCCATCAGCTCGAAGAACACGCGAGGCTTGAGTTCCACGAAACGCGTGTAGGACACGGTCTTAGGGAAGTAGCTTGCCATATGCTCCTTGATGAAGAAGAGGTAATAGTGCTTGAAATTGCGGAAAGAGCCAAAATGGTAGCACAACAGGATGGTCATGATTTCGCTCTTGGACATCTGCCCTTTACGGTTTCGCATGCGCTTATATCCCTCGTCTATGGGGGCGATATGTAGGTTTTTAGTTAACTCGGCATCTAAATTCTTGCAGAACTCATCCAATATACAAAATATTTCTGTAACTTTGTCTGTGGTAATCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP054010|777633:840054|782048_782378_-|WP_004359287.1|DBSCAN-SWA
MKKAIFTMLMLMVAMIATAKDIKTVIFTTTPQMHCANCEAKVKNNLRFAKGVKEIKTSVEEQKVYVTYDAQKTNEEKLQKAFEKFGYKAEKTTKEAKIPVHENEECENM
>NZ_CP054010|777633:840054|815797_818053_-|WP_172891297.1|DBSCAN-SWA
MNHKFLLVLLLSLSFLSLKAVGKGGEEPVDLVNPFIGTSNFGTTNPGAVCPNGLMSVVPFNVMGSDLNKYDKDARWWSTPYEYHNVFFTGYSHVNLSGVGCPEVGSLLLMPTTGKLNVDYKEYGSTYEKEVAHPGYYSNYLKKYNVKTEVTATPRSSVARFTFPKGESHILLNLGEGLTNESGAMVKKVSDTEYEGMKLQGTFCYNPQAVFPIYFVMRVSKKPTEAGYWKKQRPMTGVEAEWDVDNGKYKLYKTYHKELSGDDIGVWMNFNTEADEQVEVQMGVSFVSMANARENLDAEQRGKNFDAIRAEARAKWNDDLSRILVEGGTKTERTIFYTALYHVLIHPNILQDVNGQYPAMEGDEIRTVKEGNRYTVFSLWDTYRNVHQLLTLVYPNRQRDMIRSMIGMYEEHGWMPKWELFSRETYTMEGDPAIPVITDSWLKGLRGYDINKAYEAFRKSALTKGSENPLRPDNDEYMEKGYVALHEQFDNSVSHALEYYIADNALSRLATALGKKDDARLFHNRALGYRHYFSKEFGLLCPLMPDGTFYKPFDPKQGENFEPSPGFHEGNAWNYTFYVPHDVMGLAKLMGGQKNFVNKLQSVFDKGYYDPANEPDIAYPYLFSYFKGDEWRTQVQTRRLLKEYFKNAPEGIPGNDDTGTMSAWAVFNMIGFYPDCPGDPSYTLTSPVFDKVTIRLDKAQWGRDNLVIETVRPNDEAVIIKKIELGGKPLNRYRITNDELLKGGVLKFYLK
>NZ_CP054010|777633:840054|831285_833166_+|WP_172891298.1|transposase|DBSCAN-SWA
MHANVQTRINPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKNRSTPSLLKEHLEGLTPIEQAKADEWWIRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYNGVPDWTPGINSLYNITDKLYELKEQLERHLCSVTDDLFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINQEGFIRYSSILEGNTADPKSLPNMIDTLAKKNPSRTKDTLVVMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKVTLKEVKTEDDKDYYLEITSPSKAMTESSMNRVWKERFEMELQRINDGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKDEKKLKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNDLNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGENTEMRQCSSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054010|777633:840054|811154_813305_-|WP_004359262.1|DBSCAN-SWA
MKKRFLTLMAFAATSLFAFAQDYTQYVDPFIGTGGHGHVFLGANVPFGNIQAGPTQKKQGWDWCSGYHYSDSTVIGFGQMHLSGTGIGDLGDVSLLPTTNPAQREVKFAHRAEHVTPGYYSVMLASGVRVELTATQRVAFHRYAFPADATKGYVILNLSQGIGWDKMTSCSFKQESAKTVSGYRMSQGWAKDQRVYFVAEFSQPVKLESNERDTIGVFAFDNAEQPLLVKVGISAVSVENARLNMQKELPGWDFRNTVALAKDEWNRELSKIAIKTQDESARKIFYTAMYHSMIAPSVFNDVNGEYRGADGKTHKGDFTDYTTFSLWDTYRAAHPLMTIIHPEKQHDIAQTMLHVFKEQGKLPVWHLVGNETDCMIGNPGVPALVDIALKGFDVDKNAVFEAAKASAMLDERGMGLLKKYGYIPCDLDPEHETVAKGLEYALADACIAKLAKELGKTADYKYFSKRSQSYRDFYFDKKTKFMRGVTSDRKFREPFDPFSTVHRQDDYAEGNAWQYVWLVPHDVHGLVSAFGGEKPFVSKLDSLFIVSGDMGAEASPDITGLIGQYAHGNEPSHHILYMYNYVGQPWKAADKIRYVLKNLYHDDFDGLSGNEDVGQMSAWYILSSLGMYQVEPAGGKYIFGTPLFDEATVNVGDGKTFRIVAHNNSDKNIYIQSAKLNGKPYTRSYIDFKDIKRGGTLEFVMGSKPSQFGVKSADRP
>NZ_CP054010|777633:840054|790058_791282_-|WP_004359281.1|DBSCAN-SWA
MPFNIVYLGTNIVCTNMTCGSPQKIGCEEQPRFEQYRATDPAPILTYKDTKISACFECRVPKSFAKGIMYNLFGLLVGVAAVVAVVVAVALVIGTGGLAGVAMGAVGFLVGESLGLAAIIAAGTAVITGIAYGYSQKHDCDVVSGMSWDIYHQSIQVKGEYTIVDRSLLECPRGGLIAIIMDDTIAQETASMLTSANKEIISKKSESEFWQGVVGGATGGLNPISLGISSAFHFFDWYTANSHHKEMYSNQAYSDNIITENSNDIQSGAGLVKDGVTTYKDLKSSYETVKNISEDIIAQKRGLERLTQVAITKGTKAATKHAKNQQKVVEKLISKEAEEAGNGLKKFGKNMAGLALGVIGGIVATKIADTYDEELKLKEKDMMENFSSAIDREKQTGGMVSFTLGKE
>NZ_CP054010|777633:840054|786993_787815_-|WP_036885821.1|DBSCAN-SWA
MMILKDFDLAYSTDIHMIEDERFSHCIFHIICMGGEGSFVYNESCFHINKNDLIVISRPDEVKNIAVTNDFRIECFAANTHFLRNSLPPNNYSIRGSMSLYQDPVIPLSVENTEKIIGDIRRLRDRLGEKDAIFYREIMKSLCLTMIYDIFEFHTIYYRNQEHVDHANYVVNEFLRMLSTGITRTQRDATYFAEQLHVSLKYLSRVVKRTTGETITSYIDRATIPILRKYLDDERLSLTQISDIMNFTSLSYFSRYCSKHLGMTPSKYRSSKV
>NZ_CP054010|777633:840054|839133_840054_-|WP_004359229.1|transposase|DBSCAN-SWA
MITTDKVTEIFCILDEFCKNLDAELTKNLHIAPIDEGYKRMRNRKGQMSKSEIMTILLCYHFGSFRNFKHYYLFFIKEHMASYFPKTVSYTRFVELKPRVFFELMAFMRIQGFGKCTGISFVDSTMIPVCHNMRRNFNKVFDGLAKNGKGTMGWCHGFKLHLLCYEMGDVLTFCLTPANVDDRDPRVWQVFTKVLYGKVFADKGYIKQEFFENLFNQGIHLVHGLKSNMKNNLMPLWDKMMLRKRYIIECINELLKNKANLVHSRHRSVHNFLMNLCAALATYCFFENKPEALPVRIEKTRQLELF
>NZ_CP054010|777633:840054|802899_804183_-|WP_004359273.1|DBSCAN-SWA
MTENKKGLLALSPLLVFIVLYLVTSIVSGDFYKVPITVAFMASSIFAIAISGGYPLAKRIEIYSKGASTDNMMMMLWIFVLAGAFANSAKDMGSIDATVNLTLSVLPDNMLLPGLFLAACFISMSIGTSVGTIVALTPIAAGIATSTGSSLPFVVATVVGGSFFGDNLSFISDTTVVATRTQECKMADKFRVNFFIVAPAAVLILLVYIFLGRDIHTTGQVANVDIYRVIPYMAVLICALFGMNVMAVLTIGIVLTGAIGIIDSSYDVYGWFGSMGAGIKGMGELIIITMMAGGMLEIIRENGGIDYLIKMITRHVNSKRGAELTIAFLVSLVDICTANNTVAILTVGGIAKQIGDRYGVDKRKAASILDTFSCCAQGLIPYGAQILMAAGLAKINPVSIVPFLYYPMLLGITAFLSILFHYPRRYS
>NZ_CP054010|777633:840054|809215_809869_-|WP_004359267.1|DBSCAN-SWA
MKQLKVKRLECQQVKAADIPALFKDNSVSYNKIDTVDWAAEFPYCPQVEFAIAHKDDAILLHYRVEEDCVRAEAGTDLGPVWQDSCCEFFCSPDEEGGYYNLESNCIGTVLLCNGQGRENRTHAPAVALEQIDRWASLGREPFEMREGRQAWELTLVVPVSSYFRHTLDNLSGKTIRANFYKCGDKTSQPHFLSWNPIALPSPDFHCPAFFGELNFE
>NZ_CP054010|777633:840054|780943_781771_+|WP_004359288.1|protease|DBSCAN-SWA
MNNKNVLSATLYVILFVSLFILIQSLSFKGGKQLVSLLGGTEAADGDYLTKNGETLAITAVISSLATLILFIATKWAPVSGNYLKTRPWAVLMWSALIALGSILPLQFLAEKINLTMPAGTEEMFESIMKVSWGYVALGMMVPIAEEIVFRGAILRVLQNALGERKRWIAIVISALIFGIVHFNLAQGLHAFLIGLLLGWLYSKTGSILPGFVFHWVNNTVAYLMFNLMPQMNDGKLIDFFHGNDRMMYGGLFFSLCIFVPSLLQLIGRMPKGNK
>NZ_CP054010|777633:840054|829897_830683_+|WP_036885813.1|DBSCAN-SWA
MIINNKENNKDGQQQHITNEHPVRLSPPLEVLGEVSSIRHSPPFGGVGGGFSAVILAAGDFPTHVLPLHILRTAENLIVCDGALEDLLEYDIEPTAVVGDGDSLSEEFKQRYAHIYHPISEQEFNDLTKATLFARSHLKMDASTHTRPRFCYLGATGKREDHTLGNISLMLYYYRQLAIDPVMVTDYGYFVAASGTMRFESFPGQQVSIFNTTCKELSSNGLKWDIYPFSELWQGTLNEALSNEFTIQADGDYLIYRTHKI
>NZ_CP054010|777633:840054|791287_792187_-|WP_004359280.1|DBSCAN-SWA
MTYWEELKKKIKGKQYVEYQHIRYRNEQTVAMKINGMLISTNRLKTDYTVEKVYNTHHNIMQIAFKIDDNIASVSPEQYQAGMNMVVDLEKIKCQAVINVDMDTGHIGEIVNHEEIVLAWEDYKDYFRDKYKFLRSRETRDSVNKFLETQDKLILDQEMMKAEMKSKMFYMLIFDYYLVGKQKQNAPDIITFPSQLFKGISFPMTITPRTYKDSSDKIMYDRIGSIDEYIATLPEIVKFYNEQYKPTIQYKFNQYRPIFNISETVNEEKRYIEKAEVRLIEEVVNNIDLTILCKLRKIE
>NZ_CP054010|777633:840054|801526_801694_-|WP_172891295.1|DBSCAN-SWA
MANNLPSIPKQITICLEESKYAHGFNQENNIHSFNFNRVLSLIDNQVSKKGGQKS
>NZ_CP054010|777633:840054|805870_806812_+|WP_036885819.1|DBSCAN-SWA
MSIKSYLQKLSFRTGVIVLLMCIPFYILSFVQVFFPVSTATKGILFTVFFGLAKSFQYGGIAILGKEGYKRVKGYLKRKKQLNDKIMKNDSNRTHRYCPDLFSNPEILSGIRLIIFDFDGTLGDSQKLITDTMLATIERLNLPMKSREECARTIGLPLKECFSSIIPMSDEQAEECAKVYSEIFNEKNVPGVVKTFPGVVETLERLSSQGILMSIASSRSHRTLAKLMDELDLSKYITYLIAADDVAEKKPAAESVLKTLRHFNIEAHETLVVGDTEFDILMGRNAGTHTCGVTYGNGSKESLDAAKAEWIVC
>NZ_CP054010|777633:840054|789384_790062_-|WP_004359282.1|DBSCAN-SWA
MNKKKFQTTLSSFSIGIWRAIGFFILAPLIYTIYSYFANTGNTDNLQYLKTYINDSEIVQIELPSNREQIERKYVTNYRDQHNNLIYYFTVSFYDAKIKKYIAICMFEGIDFFNPEKRGGDLGAARIKSYFNPGNIFLVHVNKTQLHDSKYGTKENPVPVFWHKFISGTVERQIKKDNTPYDRSTKSILYFDVQDNLTAEEYRLFVTEYLIRVLDREELKRLYEQ
>NZ_CP054010|777633:840054|784678_785014_-|WP_050759733.1|DBSCAN-SWA
MIVWIGSGIMTVVCAHTGNVSVAKMEDKGHCNDNGVKNCMKIEVKTLSPTDMAHNDFYHIQPIQLSLLPQFVSDCQLLPLPILTKAPERILSLLWHSPPRQYLRLLTTLII
>NZ_CP054010|777633:840054|819427_819847_-|WP_004359252.1|DBSCAN-SWA
MKSKSQHGQVLLDSNVLIHLLRKNESVRQHILETGWRNCCVSEISIVELLYGAECSAYPEKNRTLLKDLLNQLKIIPFSVCIEEFCRQKAVLRRKGQMIEDNDLYIASTALTLGIPVATENVKHLARIEGLEVQNWVKR
>NZ_CP054010|777633:840054|797460_799917_-|WP_004359277.1|DBSCAN-SWA
MDHQYNTISIFGNRGTGKTTFILSILQQIEKTYEKAKILKIIDPTQMEEKEHVFLVILSLIDTEVRSKIETHKRNYNSGVCCYEREWNNKLSSLAKGLPTLEGLNNKQYENWDDDSYIVERGLKNVKAAYDLEKNFHELTELALKILQKEFFVLAFDDIDVDMSKGWPVLETIRKYLTTPMFVVLLSGNPTLYSYNVRLHQWNQLKNLKEHEDHDYKSQVNQLEGQYLLKVLKPENRIQLRTLLDYKRINDTSYMVKQKKEDKEKDIEKKYIDILNGLGIHKNSTQELFIDYLLGLSIRSQISILSDYNEPDIMSQINVYVSRMTAADIDVDLAVKNPVFTIISIVEYLKKLNGFAHSYLLIPNTLNHDVNGVLMGLTTIFANQVKQSPWIIFDYMLRVGYTRHLNLQLSTTAFNQILSHTGIMQDMSIKNIVLLMAAVGKANNLKLPELIRLEGLNFKAKKNQEEKENAIDNILKGDNINMTQKVLALLPLFSLGKGQRQNTELYYSVLPLLSTICMIIRSGKDKSSIKGLLSDLSLHRTYPMSSADQVVSDDPESNITSNEELSQSLGIDIEDEILDDLIIKLIQWRETFIKDNEKNPTLLLPPYLLGRIMTRFTSALINVSNKENLAELFQQHLILFLNSVMIEEVKEKFDNKVDVNNNNPVGTPQLFYDNLGKVTKINEDEKSYLDSLTFIRCLLSCPLISVFFKEEVSLEIKKHIKNFGFNDITLFDILSRAKFETKENALIKTIDITNNSLKESLERIMEEKDKEFFRTNIYDVDNLKAYYALKSLPFVNSVGQGCTKRLKDLYKKEYIDKQ
>NZ_CP054010|777633:840054|833503_834817_-|WP_004359235.1|DBSCAN-SWA
MRVVQLQEQLLENTYLQQTECEAIIPYMDDGSEVVRGVKRGREEKELCLKLSRKADSICATGSYFVGVDWIKEEELAVQVSPKMNDGFEIDYVRMLNEALAEPDNMEHLKDLLTIRFDKPSICISQKQDLLSIFLITEYLNILQRIVRKGLKKSYYRVEENLNNKVKGHILVSRTIQRNLAKGRITDNVCRYQVYDIDSPENRILKKALAFCKKQLEVYKHALDTKALEKKIRYVQPSFERVGDEISVKAMKTFKGNPVFKEYFTAVEYAQLLLRRFSYDITLVGKSQIVTPPFWIDMSKLFELYVFGKLKKIFTRKREIQYHVKAHYQELDYLLKPTEWTEPYVIDAKYKPRYKQGGGITIDDAREVSGYARLSKIYKELGLNEETALPIKCLIIYPDQDQEERFTFTKTEEPAFEKVSGYVRFYKLGIRLPVVQT
>NZ_CP054010|777633:840054|793142_794753_-|WP_004359279.1|DBSCAN-SWA
MKKILLSVALMMATFSLHATDANYQVVPLPQSITAEKGTPFVLDANTVINVASNDEAMRRNGEFLKQYIQEATGIALNGMNKKGSTITLKINAKVENEEGYVITVKGKNITVEGKTPRGVFYGVQTLRKSLPLEKAENVTFPAARIVDYPRFGYRGTMLDCARHYFKMSFIKEFIDMLALHNVNTFHWHLTEDQGWRAQIDRYPKLTEVGSKRAQTVIGRMTGLFDDTPYGGYYTKDEMREVVKYAADRYITVIPEIDMPGHMLGALAAYPELGCTGGPYKVAEQWGVFPDILCAGNPKTYEFVNNVLDEIVDIFPSKYIHIGGDEAPRIRWQHCPRCQAEIKRLGLKGSNGFPAEAQLQAHFMNQVAKHLESKGRNIIGWDEILEGDVDKGTTVMSWRGVNGGIEAAKRGLDAIMTPVNYYYLDYYQRKDNTMTLIGGFLPVETTYGYNPVPDDAAPELKKHVKGVQANLWTEYVIGRDLAFFQLLPRVAAMAETGWTENDKKDFDSFKARETRLNELYKHFGWKTCQDLYKEKK
>NZ_CP054010|777633:840054|795230_797117_-|WP_155812486.1|DBSCAN-SWA
MLLICAFIFKNLVSTINDIGSHSFYNQVIAPNLGNTSLIPPYIPQLEELKKESHGLNDLHIHLNGTVETDTLWLDFLHYPDSFYREMLESSNGNELAKEQYEQFDNWTKPRRLKTLIEKAIELRKKLFSKVNKVVQLRESFTRQSEACLYIAVLHYLSMNPENKQGAAYFHHYLLILGLVNQMSVQQPQCFGFDQFQQYTSNGLREYSEQEYIERFFQLAGNQCDNIKNLEGRFSPKDSIEKNNQLIDKIRRGWLHLNNRQDCDKSNIRLTAHFIKRADKGKDDIRFKALRLKNRKICEALISLRNSGSKNGRAIVGIDAAASEFDTPPEVFAPVFKRLRENGFQYFTFHAGEDFYHLLGGLRAIYEAITFLDLQRGDRIGHATAAGVDPGIWEHNVGCEVVVPIGAYMDDLLFVYYLISNNECKALESLMPRLYMRITELSREIFPNDEFQVYDLIYSWKKRQEDILELADSGELNNIKALKRYHQKEYVENYKKEIKVKIFEILDKNALREVQLAILKIMHHKEIAIETLPTSNIFIGYHNSFNTYHLVNWIRWEKEGKPIPPIVLGTDDAGIFATNIYNEYCHIYTLLVYEYDFCINEAFEIIRKINRDANYYTFNNDSLYAANK
>NZ_CP054010|777633:840054|779960_780932_+|WP_036885826.1|DBSCAN-SWA
MNTIYIKRGEEYELVEQVATIGFFDGVHRGHQFLISRVIDEAKRSGMASAVITFDRHPRQVLQADYQPELLSTLDEKLLLLSKTHIDNSFVLHFDTSLAALSAHDFMQEVLCKQLNVKKLIIGYDNRFGHNRSETFEDYVQYGKEMGIEVIRADAFLPNDEKVSSSIIRNDLRTGNIEAANRLLGYPYTIESRIVSGYQNGRKMGFPTANLDVNGCQQLLPASGVYAVMVRLKDSVGWKRGMMNIGHRPTFNGTTTSIEVNLFNFTGNLYGQELLVSFISKIRDEHKFDSLEALAQQLKQDKEQINRLFDETYHIQENIINTP
>NZ_CP054010|777633:840054|799979_801359_-|WP_172891313.1|transposase|DBSCAN-SWA
MRLLRATVNQQYAEIIKLNRNINALNLEIRKKDTELINLRERLAKYEKPDKNSNNSSTPPSKERIKDEVIRRTRSLRKPSGKKPGGQKGHDGHKLSCSSIPDEIIDEVPNYCTRCGESLSDTERVLDYVTQVISIPELKPVIKEIRHYVMVCKNCGERIRTAPRRRSNNVVYDSSVKTLVVYLSVVQFLPYGRIATFLREVFGLTPSEGSLVNWVNEAKRNAQPVIDKIKEYIKSSAVVGFDESGLYCKKRLDWAWIAQTVYYTLLFRADGRGSKVLVDKFGDSLERMTAVTDRHSAYFALHFLNHQVCLAHLLRKLQYLSELNTEQEWSGKVTNLFREAIHERNSNPNDVIDKVSWTRRLDNLLKQNIEEFGKKFITFKKALVKCRDYIFNFLENPMIPFDNNGSERGIRKLKIKLKNSCTFRSDFGADAFLELHSIVETAKKHDKTPYNAIQALFKV
>NZ_CP054010|777633:840054|829098_829698_+|WP_004359239.1|DBSCAN-SWA
MTLDMLGCIVGLIYIYQEYKASIWLWLTGIIMPVIYMFVYYEAGLYADFGMQIYYTLAAIYGFLYWKFGRKKGAEEIPITHYPRQLILPSLVTFLLLWAALYIILIKFTNSTVPVLDSFGNALSFIGLWALAKKYIEQWWIWIVVDIELAGLYVYKEIPFTAGLYAFYAVIAVAGYFKWRRSLPQPLRKEGSANREDLP
>NZ_CP054010|777633:840054|782472_784521_-|WP_004359286.1|DBSCAN-SWA
MNKIIYLAGLTLLSVLPATAQETAVDTTATLKDQTLSDVTVTARKASVRSLSGAINGKDILRDELFKAACCNLGESFVNNASVDVNYSDATTGAKQIKLLGLSGTYVQMLTENLPNFRGAALPYGLGYVPGSWMKSMQVSKGNTSVKNGYEAMTGQINVEYVKPEDPTGMTVNLYGNTVGRFEANADGNIHINGNKNLSTEILAHYENNWLHHDGNGDGFQDAPKVRQYNLQNRWFWKKGDYILHAGLSLLKEDRVSGQTPHAAATNPYRIDIGTDRYEAYMKHAFVLNKEHATNIALMGNVSMHKQEAQYGIKQYDVNEKNAYASLMFETNFTDEHNLSAGLSLNHDYLHQTLTLPATAVPSDYGNIFPLTRGIESETTPGAYVQYTYNLHSRFIAMAGLRVDHSNVYGTFFTPRFHLKWVPADFLTLRLSAGKGYRSPHALAENNYLMASGRRLIIDKLDQEAAWNYGASLNFLIPIGSKMLKINTDYYYTHFLSQMLIDYDSNPQELHITNLNGKSFSHTFQIEASYPLFKGLELGAAYRYNLVKSTYGGKLMWKPLQSRYKGLLTLSYKTPLGVWQFDATAALNGGGRMPESYTLASGERSWAGSYKAYGQLSGQVTRYFRHFSLYIGGENLTNYKQKNPIIGYQNPWANSFEPTMVYGPVEGAMAYVGIRLNLGKRQ
>NZ_CP054010|777633:840054|785120_786851_+|WP_036885823.1|DBSCAN-SWA
MFNYRPSRRTLYVGGGILLILLLIYIVFRCLPPSQEEVDKSAVAIRQEAYYTLEADGKPLAYFADYVDSAFVGGSINKDSIHTRSMTQRGYWVNRLPVVPSCHGRILIRWNYKPLIIVNLKGKGVLRLIRQTMAQMDSELDGLQTKRNEMGYYLRVHSVQDYGYNKIAEYHTEVVQQMDSLRRMMKVLDSLSTSSAQLRIRQQNRYAIQTSSKKAKPTVCNRLEIDKKNDCVLLQTESKRTPIRLITRLQKSGAIDALNTYYKTHAATISSLAKGICIAGGRYEGESKKNVPNGYGKYYGDDGSFYDGHWKDGKRDGFGIYVAPHEYLQVGEWKADVFKGERLTYTPDRIYGIDLSRHQHEKNNKVYHIYWNKLRITDLGTLSTKTIKGNVDYPVSFAYVKSTEGCTVLNTYYEADYKAARAHGIRTGTYHFFSTMSPGAAQAAYFLKCSKFNKGDLPPVLDVEPTDAQIVAMGGAEVMFRNIRAWMSLVQKRTGKRPILYISQTFANTYMPLAPDLGDNYHIWIARYGEYKPNFKLAYWQLSPDGKVRGIHGDVDINVFNGYRNQYEEFLKRHCF
>NZ_CP054010|777633:840054|821272_822112_+|WP_004359248.1|DBSCAN-SWA
MNSKIKLLLIALTLSLSANAQEMKEQDVFKHTAIDTTQLIVSYDLTVKYDLSGQNNPDNEKVYTYIGRKVCQSFVESEHNADLRMAKAFLRNGKRGSRASMKLVANVGETFIGYPKGKTTVIYNMDGAGSYLYQETTPKMQWKLTTEHKMLLDYDCTAATCSYRGRNYKVWFTTKIPLSYGPWKFTGLPGLVMEAETKEGDYHWTVTGIEKPKTATPIYFLDRNYVKTSRENTRKQERLLLKDPAGYLESYGYNFTTTNFNGQVVKLTLFTFDNPLERE
>NZ_CP054010|777633:840054|824810_825230_-|WP_036885816.1|DBSCAN-SWA
MEKKVYFAGSIRGGREDAAVYKRIIDYINRTDTVLTEHIGLGSLNVKARTKEDDVHIYERDTEWLRSSDVLIAECTNPSHGVGYELAYAEARNIPVHIFYDKRKANISAMLNGNAYFKVYPYENEAEIYPFLDIILGNK
>NZ_CP054010|777633:840054|813380_815456_-|WP_004359260.1|DBSCAN-SWA
MRKKVLLSAVFLLFAAAVSMPVAAQNIIPQPENISLLKGQFKLNKGTKIVTNLTGSDFKVLNQYTSEVLKHPLAYAKNPSKQGIFRLICKGTAQQAAQAMDSVRLQGYELEVTPKGITIQALTPTGLFYGLQTVRQLEKDGQIACVKVKDAPRFAYRGLMIDCSRHFWTKDFLKKQIDAMAYFKLDRFHWHLTDGGGWRMEVKKYPRLTDEASYRTQSDWTKWWMDNDRKYCHKNTQGAYGGYYTQEDIKDIVRYAAARHIEVIPEIEMPGHSDEVVYAYPELSCTGKPYTQSDLCVGKEATYSFMENVLKEVMQLFPSKYIHIGGDEAERRTWKTCPDCQKVMKENHLKDVAELQSHFTHRMEEFLNRNGRKLLGWDEIMEGKLAPNAAVMSWRGTEAGIEAATSKHHVVMAPQQFYYLNMYQDNPMEQPKAQGGYTRLDKTYNYEPIPAEYKGSNLEKYMDGVQACVWTEFIAEPSHLEYMLYPRLFALAETGWTKKRTGYDNFRKRAVVNVDRLKRAGYNAFDLSKEKGSRIESRSVTQHEALGKPVTYLGRYAEKYRAEGDNTLTNGLRGDWGYLEGRWQGFIDSTGVDVVVDMGRVTDIRDVRVDFMHLYESVIYTPETIELMVSEDGKNFKTIDTVRPGIKASEDYLVYPYKWKGDVKGRYVRVKALPREKGAWIFTDEIIVNQK
>NZ_CP054010|777633:840054|809865_810957_-|WP_004359265.1|DBSCAN-SWA
MPNFNDVVSQFRIEGTVESVSPIGNGLINETLRVKTVDANTPDYILQRINNAIFTDVDLLQHNIELVTDHIRHKLIEKGETDIERKCLRFVQAKDGKTYYKDADNLYWRVSVFIPNAVTKEEVNPESAFCCGETFGNFQNMLVDLKEPLGETIPDFHNMELRLRQLREAVSADKAGRVASVKDMIAELESYADEMCLAERLYREGALPKRICHCDTKVNNMMFDKDGKVLCVIDLDTVMPSFIFSDYGDFLRTGANHVAEDSDNYDAVGLKEDVFCSFTEGYLSTAGNFLTPVETSHLPYAVALFPYMQCVRFLTDYINGDVYFKVKYPEHNLVRSRNQLLLYRDVRRHDQMMADFVKKTLKQ
>NZ_CP054010|777633:840054|777633_778851_+|WP_172891293.1|transposase|DBSCAN-SWA
MLITNLISRYMKLCKAAFSAEDGAKLNKSIQTNVMEMLFLLMVIPRKCNFTQMGRYGKRGEQCYRQTAERSVNWLEINMWLSAFAFKQGKGLNAIVIDPSFIKKAGKHTPYVGTFWSGCAGAVKHGLEILGIGVIDVDLHECMMLKAVQTTLEKGEEKKEMSLYDWYTKVLEDDKVTLQRICKVLVADSAFSKRPFIDKVMKMGFHVVSRLRHDAALFYTWDGEPTGKPGRPRIKGDKIDVRNIDISKGNELDLGETKGKAYALKAWCKSLHRVVSIVIHELPNGVRRLYFSTDESMSGRDVMEYYTTRFQEEFCFRDAKQFLGLTDCQARDKRKLEFAFNSSFTALNVTKIMCKELGTSIGRLKAQMVNAYYAQRIIDVFEKNPNTPLNKERINDIFSFAADAA
>NZ_CP054010|777633:840054|826357_828742_+|WP_036885814.1|DBSCAN-SWA
MKRIILFTAALTCVAAIKAQTVTDTLRQQQLDEVVVAGVRAPKSAPYAVSNIKKTELEAFSKSGRELPFLLSQTPGVLAWGENGLGTGTAAMRIRGAAGSRINITLDGVALNSPEDQTVFWANMNSYASLMNSVQIQRGIGTSTNGDGAFGGSVSLATSAPSTKPSVEVSGSYGSYNTYNAGVKFSTGLLFNHLVFDGAYHETATDGYVHGTSGRSGSYYGGLTWLGDNFRISYKNIGNFEKTGQAWNGVVTGSNDLSLMDGTYGAKTGITTYKDMYERGLGKFNQLYEYLQTDANGAFVKDANGNYQTARYTMRDGSFWNKTTDNFYQNHNLLSFAFHPSNHWSHNVTLNYTYGYGYYSEFKHNTKFEKFGLAFTDSKGKFIKKSDFVRLKGLSQHTYGIVYTSNYKDESWDVTGGLNLQQFRGSHFGYLTYIKNEEADAKYRAGGNDYKYYDSKAHKYDYSGFFKAKYNFADYWNVFMDLQIRHVEYMTDGQNDRFYKVGSGYQNQLLDVNERYDFVNPKAGISYYRGGHKAYASIAHASREPERNNFTNNGSYPAPSPERMVDIEMGYQYNGRNWRAGVNLYYMNYNNQFVQTGAQSDIGANLTTNIKDSYRMGAELEAGWSPLSWLTVEGNAALSRNIIKDFDEMASVDWEASFRKIHYNHSTLAFSPSAILNGMLNLHYKGFEAVWHTNFVSRQYLDNTENMTRSLPCYSQTNINLSYTLRPSKHIAGLKEAVFGVNLNNIFNRHYAASGWVYSSILDHDGHPNENRYTQIGFIPMAGFNVMGSVALKF
>NZ_CP054010|777633:840054|819843_820122_-|WP_004359250.1|DBSCAN-SWA
MAGIMTNIENNTIRMYWNALRSMSKNIRLGLAVKLTNSVLEEERKEMSDEAYTEEMLNKFFGKWEGNETAEELMGIIKQNSSSSEPISFEGV
>NZ_CP054010|777633:840054|838389_838734_-|WP_050759732.1|DBSCAN-SWA
MKTYDFHYSVHEVDGKLFKLIECSTWPRLNVQVIDTTPDRFEDDLNVIKSRSLCGYSPHDKTFILKHAGGEGNGELKQSNIDEIFDGMKEIMNAAVKWWRENHPTPAPPQKGGE
>NZ_CP054010|777633:840054|788091_788937_+|WP_004359283.1|DBSCAN-SWA
METIKLSNGVEMPLLGYGVFLVSPDECERSVSEALKVGYRLIDTAQIYGNEEGVGRAWRKSGLRRDELFLVTKVWPSNAGEEKAAASIEESLRKLDTDYIDLLLIHQQYGDIYGTWRAMEKAYRSGKVRAIGVSNFQAGRFFEFAHYVDVKPMINQLQCNVMAQQNDIVPVLNETDTKMMAWGPLGGEGVDGIVQNEVLAAIGKKYGKSAAQVALRWLTQRGIVAIPKSVHVERMQQNFDIFDFSLTADEMTEVAALNQQDAGFIDFNSLSFVKYLIEKYG
>NZ_CP054010|777633:840054|838813_839098_+|WP_155812479.1|DBSCAN-SWA
MSHREKECTEAYCIQGNGSHRGTVGAWRNEGYLPVLLEILCPKHLPQNLSGICTLHLRRSLCHWHLPDIALSSVLSVALCALLCMHLTSSIHIS
>NZ_CP054010|777633:840054|801979_802795_-|WP_004359275.1|DBSCAN-SWA
MDIIQRNFFRILCSGAFGTQSNLEPMSPFKWRRLIQMVEAQQVMPIFINGIARHAMDEGLNLPESIITDIKAKQEERKTLTARIPKTVRLSNALLNRRLKNLIYNELHSIDTSIEAIDMLKLIVNNSETMFTRGMNLGGIITMGEYLRTRGNKVDFVKLENWLNTLQLSAMAELQGNVLISVFGFEEDEIPFVSKSDPNAYRLTLRSISDLAKDTAHEWHFKQNVVGFVQNNSSVLRRNVRRSLRYVSYAPIETTSNFFSNFVRSLSEIEE
>NZ_CP054010|777633:840054|822165_824721_+|WP_004359246.1|DBSCAN-SWA
MAQNSQGDSLTITGRVVDNKHQPMDGCILIIIQEKDSSILASSVTNEDGRYAISYPRTNDNLLLSLTGFNIKRQIKRITPTSQTVNFNTTYESITLKEVEIKARKLWGSRDTLNYLVSAYMKGQDRTIGDILKQLPGITLEGGMVKYQGVPINHFYIENMDMFAGKYSIATNGIKAEDVSTVQVMENHEHIKALQDQIPPESAAINLRLKKKAKGRWLKTIDLGVGFDSNGLLREVNAALMYFAQRQQHVFYYETDNNGSSVDWFKSYYGGSNIGVSRLTSIIFPGSSPIGKSLRNNQHNLCFSNLNKLSETAEIKYNITYRHDIQRQSSYSQTTYLLPDASTRLMTEDISARNTTNAATMQLHFENNGSKTYLKNTLDLAGNWSDDNGLALSNNARIQQHAFNRNLGLNNHTEWIQRTTNGGGFKLKTTNFVQTNPQALTIEGDMQVRQDARLSNMGSYNSLTLIRNIRKHNWSLAPSAELNIEYVGLKSLLNDTAVTMATSGDMGYLQMKSNLGANLQYVKNTFRLSFNLPLSFNYTKVDNEPIANETTKGKRTTLLFSPSFTMLWKATDNWTLSAGGSYGMFPTSWRSLFTAYLMSNYRTLNRYKMNLSENKSASIHGKIHYKNIPHQFFAYLSGAVSRSWSDMIYGTTIDQNAHTLLQAEYAPNHQNNFSMTANVRKEIAWHDMSIGATADYSTNTSKILRQSVITDYQYNSFIISANLTFNLLKNTRLTENCRWAISQSKSGNYKNIIRNFSNEVALSMAFIPDRLILNTNLQYTHNSGFTDKKDYTFMNLSITFKTKKKIQFVLNFDNIFNTKTFIYRSNSNLSESYTLYQLRPRSVMLTTHFAL
>NZ_CP054010|777633:840054|807416_808634_+|WP_172891296.1|transposase|DBSCAN-SWA
MLITNLISRYMKLCKAAFSAEDGAKLNKSIQTNVMEMLFLLMVIPRKCNFTQMGRYGKRGEQCYRQTAERSVNWLEINMWLSAFAFKQGKGLNAIVIDPSFIKKAGKHTPYVGTFWSGCAGAVKHGLEILGIGVIDVDLHECMMLKAVQTTLEKGEEKKEMSLYDWYTKVLEDDKVTLQHICKVLVADSAFSKRPFIDKVMKMGFHVVSRLRHDAALFYTWDGEPTGKPGRPRIKGDKIDVRNIDISKGNELDLGETKGKAYALKAWCKSLHRVVSIVIHELPNGVRRLYFSTDESMSGRDVMEYYTTRFQEEFCFRDAKQFLGLTDCQARDKRKLEFAFNSSFTALNVTKIMCKELGTSIGRLKAQMVNAYYAQRIIDVFEKNPNTPLNKERINDIFSFAADAA
>NZ_CP054010|777633:840054|804621_805686_-|WP_004359271.1|DBSCAN-SWA
MAEKIRIKDIAERAGVSVGTVDRVLHKRPNVSESALKRVEKVLKEMNYQPNVYASALAYNKSYTFYCLIPKHSSEAYWEEIEIGAMKAVEARRDFYIDLEIMYYSRLDPHSFIETYQKCLRQNPDGVILVPTTLEVTRLFTDELHDRNIPFILLDSYMPSLQPLSFYGQDSIQSGRFAARMLMLIAQKEESIMLMKQTKDGKMASRQQENREVGFRHYMEENFPNIKILEVNLPLDEERKRYDHILEKFFSEHPEVHHCITLNSKAHIVGKFLLKTHRHNVQIMGYDVVHKNADCLREGSISFLIAQHAYQQGYFSVDSLFRAIVLKKKVEPVNYMPIDLLMRENIDFYHRSWG
>NZ_CP054010|777633:840054|818265_819240_-|WP_004359255.1|DBSCAN-SWA
MKSLKDILPWEDRPEGCKDVMWRYSKNPIIDRYHIPTSNSIFNSAVVPFEDGFAGVFRCDNKAVQMNIFAGFSKDGVNWEINHEPIKFEAGNTEMIESEYKYDPRVTWIEDRYWITWCNGYHGPTIGIAYTFDFKKFYQCENAFLPFNRNGVLFPEKINGKYAMLSRPSDNGHTPFGDIYISFSPDMKYWGEHRCVMKVTPFPESAWQCTKIGAGSVPFLTDEGWLLFYHGVITTCNGFRYSMGAAILDKDNPEKVLYRTRPYLLAPNAPYELQGDVPNVVFPCAALQDGERVAVYYGAADTVVGMAFGYIKDIVEFTKNNSIL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172891293.1|777633_778851_+|transposase	transposase	A0A218MNH3	uncultured_virus	1.3e-55	34.4
WP_036885826.1|779960_780932_+	bifunctional riboflavin kinase/FAD synthetase	A0A1V0SJE1	Klosneuvirus	7.6e-11	34.9
WP_004359288.1|780943_781771_+|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004359287.1|782048_782378_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_004359286.1|782472_784521_-	TonB-dependent receptor	NA	NA	NA	NA
WP_050759733.1|784678_785014_-	hypothetical protein	NA	NA	NA	NA
WP_036885823.1|785120_786851_+	glycosyl hydrolase family 25	I3VYU7	Thermoanaerobacterium_phage	1.0e-10	26.2
WP_036885821.1|786993_787815_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004359283.1|788091_788937_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.7e-47	40.1
WP_004359282.1|789384_790062_-	hypothetical protein	NA	NA	NA	NA
WP_004359281.1|790058_791282_-	hypothetical protein	NA	NA	NA	NA
WP_004359280.1|791287_792187_-	hypothetical protein	NA	NA	NA	NA
WP_004359279.1|793142_794753_-	beta-N-acetylhexosaminidase	A0A2H4UUW7	Bodo_saltans_virus	1.3e-10	30.9
WP_155812486.1|795230_797117_-	hypothetical protein	NA	NA	NA	NA
WP_004359277.1|797460_799917_-	hypothetical protein	NA	NA	NA	NA
WP_172891313.1|799979_801359_-|transposase	IS66 family transposase	NA	NA	NA	NA
WP_172891295.1|801526_801694_-	hypothetical protein	NA	NA	NA	NA
WP_004359275.1|801979_802795_-	hypothetical protein	NA	NA	NA	NA
WP_004359273.1|802899_804183_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_004359271.1|804621_805686_-	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_036885819.1|805870_806812_+	HAD family hydrolase	NA	NA	NA	NA
WP_172891296.1|807416_808634_+|transposase	transposase	A0A218MNH3	uncultured_virus	1.6e-55	34.4
WP_004359267.1|809215_809869_-	hypothetical protein	NA	NA	NA	NA
WP_004359265.1|809865_810957_-	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_004359262.1|811154_813305_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004359260.1|813380_815456_-	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_172891297.1|815797_818053_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004359255.1|818265_819240_-	glycoside hydrolase family 130 protein	NA	NA	NA	NA
WP_004359252.1|819427_819847_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_004359250.1|819843_820122_-	hypothetical protein	NA	NA	NA	NA
WP_004359248.1|821272_822112_+	GLPGLI family protein	NA	NA	NA	NA
WP_004359246.1|822165_824721_+	TonB-dependent receptor	NA	NA	NA	NA
WP_036885816.1|824810_825230_-	nucleoside 2-deoxyribosyltransferase	NA	NA	NA	NA
WP_036885814.1|826357_828742_+	TonB-dependent receptor plug domain-containing protein	NA	NA	NA	NA
WP_004359239.1|829098_829698_+	nicotinamide mononucleotide transporter	NA	NA	NA	NA
WP_036885813.1|829897_830683_+	thiamine diphosphokinase	NA	NA	NA	NA
WP_172891298.1|831285_833166_+|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_004359235.1|833503_834817_-	hypothetical protein	NA	NA	NA	NA
WP_050759732.1|838389_838734_-	hypothetical protein	NA	NA	NA	NA
WP_155812479.1|838813_839098_+	hypothetical protein	NA	NA	NA	NA
WP_004359229.1|839133_840054_-|transposase	IS982 family transposase	NA	NA	NA	NA

2. NZ_CP054011

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP054011_1

• CRISPR_ID: NZ_CP054011_1
• CRISPR_location: 749480-749567
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_1

Consensus_repeat	Method
ACATATTGCTTTAATGACATATT	CRISPRCasFinder

spacers of NZ_CP054011_1

>1.1|749503|42|NZ_CP054011|CRISPRCasFinder
GCTTTAATGACATATTCTAAGGGAAGACTGAATGACATAAAA

CRISPR arrays and Neighbor proteins around NZ_CP054011_1

CRISPR arrays

The CRISPR arrays of NZ_CP054011_1

>merge|NZ_CP054011|1|749480-749567|CRISPRCasFinder
CCAGAATGACATAAAGACATATTGCTTTAATGACATATTCTAAGGGAAGACTGAATGACATAAAAACATATTGCTTTAATGACATATT

>NZ_CP054011|1|1|749480-749567|CRISPRCasFinder
CCAGAATGACATAAAGACATATT	GCTTTAATGACATATTCTAAGGGAAGACTGAATGACATAAAA
ACATATTGCTTTAATGACATATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004361270.1|755595_756204_+|DUF4924-family-protein	unknown	unknown	gnl|CDD|374461
NZ_CP054011.1|WP_004361248.1|741060_742335_-|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|185104
NZ_CP054011.1|WP_004361268.1|754899_755586_+|LysE-family-transporter	unknown	unknown	gnl|CDD|224199
NZ_CP054011.1|WP_036886806.1|740084_741074_-|glycosyltransferase	unknown	unknown	gnl|CDD|182223
NZ_CP054011.1|WP_004361279.1|760566_761052_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004361246.1|738851_740051_-|glycosyltransferase	unknown	unknown	gnl|CDD|379337
NZ_CP054011.1|WP_004361262.1|750784_752581_-|chloride-channel-protein	unknown	unknown	gnl|CDD|238233
NZ_CP054011.1|WP_155812524.1|743504_744980_-|lipopolysaccharide-biosynthesis-protein	unknown	unknown	gnl|CDD|240533
NZ_CP054011.1|WP_172891361.1|737679_738825_-|EpsG-family-protein	unknown	unknown	gnl|CDD|379716
NZ_CP054011.1|WP_004361254.1|746182_746644_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004361252.1|745005_745989_-|acyltransferase-family-protein	unknown	unknown	gnl|CDD|226122
NZ_CP054011.1|WP_004361274.1|757230_758799_+|peptide-chain-release-factor-3	unknown	unknown	gnl|CDD|179105
NZ_CP054011.1|WP_004361272.1|756216_757101_+|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl|CDD|367904
NZ_CP054011.1|WP_004361264.1|752593_753163_-|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl|CDD|376519
NZ_CP054011.1|WP_004361249.1|742367_743477_-|glycoside-hydrolase-family-99-like-domain-containing-protein	unknown	unknown	gnl|CDD|211420
NZ_CP054011.1|WP_004361282.1|761172_761769_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|183566
NZ_CP054011.1|WP_004361258.1|748188_749433_+|acyloxyacyl-hydrolase	unknown	unknown	gnl|CDD|378181
NZ_CP054011.1|WP_004361260.1|749703_750726_-|methionyl-tRNA-formyltransferase	unknown	unknown	gnl|CDD|234567
NZ_CP054011.1|WP_036886809.1|753766_754768_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NZ_CP054011.1|WP_004361256.1|747422_748172_+|outer-membrane-beta-barrel-protein	unknown	unknown	gnl|CDD|372635

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004361270.1|755595_756204_+|DUF4924-family-protein	gnl|CDD|374461	pfam16271, DUF4924, Domain of unknown function (DUF4924). This family consists of uncharacterized proteins around 180 residues in length and is mainly found in various Parabacteroides and Bacteroides species. The function of this family is unknown.	1.83274e-104
NZ_CP054011.1|WP_004361248.1|741060_742335_-|nucleotide-sugar-dehydrogenase	gnl|CDD|185104	PRK15182, PRK15182, Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB.	3.01239e-168
NZ_CP054011.1|WP_004361256.1|747422_748172_+|outer-membrane-beta-barrel-protein	gnl|CDD|372635	pfam13568, OMP_b-brl_2, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.92706e-05
NZ_CP054011.1|WP_004361246.1|738851_740051_-|glycosyltransferase	gnl|CDD|379337	pfam13692, Glyco_trans_1_4, Glycosyl transferases group 1.	0.00012393
NZ_CP054011.1|WP_004361262.1|750784_752581_-|chloride-channel-protein	gnl|CDD|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	1.7439e-99
NZ_CP054011.1|WP_155812524.1|743504_744980_-|lipopolysaccharide-biosynthesis-protein	gnl|CDD|240533	cd13128, MATE_Wzx_like, Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.37678e-13
NZ_CP054011.1|WP_172891361.1|737679_738825_-|EpsG-family-protein	gnl|CDD|379716	pfam14897, EpsG, EpsG family. This family of proteins are related to the EpsG protein from B. subtilis. These proteins are likely glycosyl transferases belonging to the membrane protein GT-C clan.	2.049e-13
NZ_CP054011.1|WP_004361274.1|757230_758799_+|peptide-chain-release-factor-3	gnl|CDD|179105	PRK00741, prfC, peptide chain release factor 3; Provisional.	0
NZ_CP054011.1|WP_004361252.1|745005_745989_-|acyltransferase-family-protein	gnl|CDD|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	1.97886e-10
NZ_CP054011.1|WP_036886806.1|740084_741074_-|glycosyltransferase	gnl|CDD|182223	PRK10073, PRK10073, putative glycosyl transferase; Provisional.	1.73449e-38
NZ_CP054011.1|WP_004361272.1|756216_757101_+|dTDP-4-dehydrorhamnose-reductase	gnl|CDD|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	2.30256e-112
NZ_CP054011.1|WP_004361264.1|752593_753163_-|threonylcarbamoyl-AMP-synthase	gnl|CDD|376519	pfam01300, Sua5_yciO_yrdC, Telomere recombination. This domain has been shown to bind preferentially to dsRNA. The domain is found in SUA5 as well as HypF and YrdC. It has also been shown to be required for telomere recombniation in yeast.	1.2151e-51
NZ_CP054011.1|WP_004361249.1|742367_743477_-|glycoside-hydrolase-family-99-like-domain-containing-protein	gnl|CDD|211420	cd11579, Glyco_tran_WbsX, Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases. Members of this domain family are found in proteins within O-antigen biosynthesis clusters in Gram negative bacteria, where they may function as glycosyl hydrolases and typically co-occur with glycosyltransferase domains. They bear resemblance to GH71 and the GH99 family of alpha-1,2-mannosidases and may share a similar cataltyic site and mechanism. The O-antigens are essential lipopolysaccharides in gram-negative bacteria's outer membrane and have been linked to pathogenicity.	1.36366e-165
NZ_CP054011.1|WP_004361282.1|761172_761769_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|183566	PRK12513, PRK12513, RNA polymerase sigma factor; Provisional.	2.82452e-42
NZ_CP054011.1|WP_004361258.1|748188_749433_+|acyloxyacyl-hydrolase	gnl|CDD|378181	pfam09411, PagL, Lipid A 3-O-deacylase (PagL). PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.	4.31965e-07
NZ_CP054011.1|WP_004361268.1|754899_755586_+|LysE-family-transporter	gnl|CDD|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.68853e-12
NZ_CP054011.1|WP_036886809.1|753766_754768_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.89203e-65
NZ_CP054011.1|WP_004361260.1|749703_750726_-|methionyl-tRNA-formyltransferase	gnl|CDD|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	1.03262e-132

Protein sequences

>NZ_CP054011.1|WP_004361258.1|748188_749433_+|acyloxyacyl-hydrolase
MRKLLFIPSLLLSVVASAEEYDSIAIPKVGIEVHYTPAQTLCIDKEPRIWTKTKETHTVAAQLNITPSENDFARDYNYPTFSVGLRYNFNHGTTMHKDNPWGEAQPVDYTSKLGNFLTLYGTFNRPLYRSEHWQWGYYLGTGVGYTSLKYNQKNNIDNEYIGSHLNIFFTAGLYGQYKVAKEWNIKAGLDFAHHSNGAMARPNKGANYLGPFLGIVYEPEKETTKVAKGNTHPKDPFQKYWFTEFTLGIGGKTLLEDWQQTQFETPQGHPDYRREQFAFYGAYSFHTHLLYRYAHRWASGVGFGLFYGDYANRVAQHDKEHGYTGEKHSPWSLSIEGRHEIFYGNMSVRVSLGYYLYRHMGYKSRNGLERPYHEQVGVFYSFPKLKNLTLGFSVNAHATKADFTELQITMPVRL
>NZ_CP054011.1|WP_004361256.1|747422_748172_+|outer-membrane-beta-barrel-protein
MKKIILIAAILLGALTNGQAQVINKNYAKRIGQAVKEGYQDVKEVIVQDTKPTGEHTIWDIYAAPKVGLKLSNLSGIDGKMNIGCVAGASFEVFIANNIAIDAELLYSHQGSSGVYRNIDTTDDYGNPVVQEYGPYNFNLHYFNMNYLVRWYPWADLPWSFTTGVHTGYLISAHAKRKNGEDINLKNNIYRGDVSIPFGVSYEWKQWQVEARYSLSLRKLTKNAEAKDLLKNARNSMLEVTLGYRIQVL
>NZ_CP054011.1|WP_004361254.1|746182_746644_-|hypothetical-protein
MDTNESLSLETFPKSYEACFLENCAVREDCLHHLYFKLQPTSNTWGDAIFPSALMPENLVNGCCRMYQAKKLVTCYVGFTHFFDEVRRKDLPSLRKEVYTYFRGRSNFYRYGNAERGYLYTQSMADDVKALFIEYGYNEPKYERTFKSIVFYE
>NZ_CP054011.1|WP_004361252.1|745005_745989_-|acyltransferase-family-protein
MTLNQRINWIDWAKVFAIYLVALGHLLSKTGSEGYIFNFIYSFHMPFFFFISGYLFRIKENGFVDFLKSSFRSLLVPYILLNLIGNAFLIPTWVLARHWPIDQLFYFITADGRGEPGPTWFLVCLFQVRLLSYFIVRKTPVWRLLVVLFCILIAYLFPFHLYWRIDTVFMVIPFYIAGYELKSKLSFFSSKIPFFILLLIVLSLTMIMGYSNVYLRLFGDYPLLYYPYAFAGIFMLISLSFMFDKYNFKFITILSIGTIVIMGLHGIVFLYVETIFKDLFSLDYIFLTFTGKLLLSSISLLLLYYPIIWIQKYFPIVMGGRSRYGRE
>NZ_CP054011.1|WP_155812524.1|743504_744980_-|lipopolysaccharide-biosynthesis-protein
MLYMRAILLMGIGLYTSRVILHVLGVTDFGIYNAVGGIVAMFGFISSSLSNATSRFITIAIGQGNQEYTNRTFGTIKYIYYLLCILVVLLVETVGLWFLYTKMTIPSDRMVAAFWVFQYSILSTVIGFICVPYNSAIIAHERMSAFAYISLFDAILKLLICLLLQITPYDKLVVYATLLFLVEIIDRIIYAVYCSKHFEEVRAPAKLDKKQLKEILTMSGWTLSGNIFWILNTQGVNLILNVFFGPVVNAARGIALQVQGVMGQFVLNFQTAINPQITKSCSQENFKRMGELLMLSSKFSYFLLFLMSLPVFLEAPFILNCWLGTVPSHTVVFLRIVLVGALISSLSNPLWISILAIGKLKKYMIWDNIIQFLVLPSLYFIFRFLNGDPAWAFIVVGISALIGLIVRAWITLPLIHYSRREYIWKVILPLSVVTLLSPILPLFLGKFVLSPILNFLFVIMISFFSSVMVIFVLGLTKNERSFIVNKVYSFF
>NZ_CP054011.1|WP_004361249.1|742367_743477_-|glycoside-hydrolase-family-99-like-domain-containing-protein
MKPKIIAFYLPQYHPTPENDEWWGKGFTEWTNVGRAKSLFKGHDQPRVPTELGYYDLRLPVVREQQAELARKAGVTAFCYWHYWFGNGKQMLSEIFDEVLSSGQPDFPFCLGWANHSWFAKSWDKTTPNKLLVKQEYPGIEDQIQHFQYLLRAFKDPRYIKVDNKPFLLIFDPFTLPDIYIENFRKFAKEAGFPDLYIVANSYKIELSPNYFTEKGYDAVSYARLSSLWAEKIRRMGKLERNFFSMYRVFKQLVTGRPRGARDYSKDFPKLITKQDKDRRIIPQIVPQWDHSPRSEHAADLIYYNSTPESFYLHCLDAFEVLKDKSEDEQILILKSWNEWGEGNYMEPDISNGDGYIKALRKALNKVSK
>NZ_CP054011.1|WP_004361248.1|741060_742335_-|nucleotide-sugar-dehydrogenase
MISKEIKIAVIGLGYVGLPLARLFSTKFQTVGFDMNQGRVDALMAGHDATLEVSDELLQSALENGFVCTTNLEDIKDCNFYVVAVPTPVDVNNRPDLKPLWGASETVGKVISKGDVVVYESTVYPGVTEEECLPVVEKVSGLTFNKDFFAGYSPERINPGDKEHTVEKIKKVTSGSTPEIADLVDNVYNAVLINGTHKAPSIKVAEASKIIENSQRDVNIAFMNELAKIFNAMGIDTRDVIDAAASKWNFIKLNPGLVGGHCISVDPYYLIQKAQVYGVLPRIMSAARRLNDGMGDYVANQTIKMMNKKGALVKDSNILILGITFKENCPDVRNTKVVDIYSTLSEYTSNITVLDPWANVERVKKEYGIDAVASLPKDKKYDAIILAVSHKQFADTDWREKLNENGVIYDVKGFLNRDIVDGRL
>NZ_CP054011.1|WP_036886806.1|740084_741074_-|glycosyltransferase
MDDYKYKLSIIIPMYNAEKYIGICLDSILGSNLLKEEYEIVIVNDGSQDKSPEIAQDYALRYSNVTYLTQENQGQSTARNYGIKTCQGEYVWCVDADDKVISELLPKIIEALDEYKNLDILAIQLQNVTEGGQYLDVECSQPTLEHNKVLSGVEAVLSGYNPSSICALITKKQLFIDNNIFFVKGITHQDVELTYRLMPCATNVVFSDITPYLYIYHPNSTSKSMVPEKKIKYIKDDIYIINSFRRLALSFKDINPQLYSVIFNRSQNVLFGLVYSLYKNKKEWGKLGINSVIIDEMKKEQLYPMKGHFDSLKKSLFVKLFLNIPCLIK
>NZ_CP054011.1|WP_004361246.1|738851_740051_-|glycosyltransferase
MKVTMISVMMPAAENIRGTSALPYHLLAGRDRSIEVILYSYNLNRLSKEQIDSVAKELNIKICLLPVPWWYNFFLRFLLPFRILLNYPIGNYISLSSSQLDTIINDYPDAIWIYGEELSRVSCQLKDFRRIHTLPDCESLYYYRMLGKRFAIRNRIRFWRSAFMYPKYLNMEKQFDTSSNIHYHLVGKEDVNFLEEICPGIQAHFLRHPHYQVAKPAKVISFNSPKIKVLFAGQYNLYMQQDADMLIDCLIKSKDLSELKEHYVYTFLGKGWDNHVERLNKAGYETHHIKFAPDYIEEICKHDIQVTPICIGTGTKGKVLDAIANGLLVVGSWYALENIAVEHNVSCIQYEEIKDVVNILKKIHLNPSKYEAIAECGRENILQKHNGETTSKELFCLFK
>NZ_CP054011.1|WP_172891361.1|737679_738825_-|EpsG-family-protein
MIVYLFIFILVLFINSLAIKYNYNRDRALFFSLVILAVFVGLSDMLGGYDRYIYASLFDDIADITRVGGNYKDASIFTLYPSEIGYIGSNVLISFITSNRYIFILLYTLIIYFLYYFSLKKYCINYPFAIMLFMGLMFFFTFTYFRQMVGVGIAWFAIRYVYKKELYKFIICVLVAASFHNSAIILFPLYFLPIKRFSQRSIIIIMSICLVLGLSGGPSALFRLYGDVTDMQYRTDSYAEQETGFRYEYIIEAFVFLYFILKNYSLIPTTKKNIVLLNTSLGFCAILLLFVLSLNGGRLGWYYLIGVISTLSLIANNIKSNNLTRKIIPIICFLLFFRIVYYWGFLLSPYKTFFTNGVREYDPIYEKYEYDEKYSIDKFYR
>NZ_CP054011.1|WP_004361260.1|749703_750726_-|methionyl-tRNA-formyltransferase
MKKENIRIVFMGTPEFAVESLKTLVQNGYNVVAVVTQPDKPVGRHQEQLQPSPVKLYALEHNLPVLQPVKMKDADFIDELRSYKADMQVVVAFRMLPEMVWSMPRLGTFNVHAALLPQYRGAAPINWAVINGETETGVTTFFLDKDIDTGRIILQKPFAIPDTADVEYVYDGLMYLGAKIAMETIDLIASKLPEDSLDNVDFSAVLDGISAPQVCEDAELHHAPKIFKETCEINWNQSAKKVYDFVRGLSPYPGTWSTLCSIEDNGVKPLVMKVYKTAKSDRTSVGTPGTLVVEKTRLYVNTSDNLLELLDIQLTGKKRMDVRSFLNGFKDIEKYLFQTE
>NZ_CP054011.1|WP_004361262.1|750784_752581_-|chloride-channel-protein
MKVSGSQGIISRLDNWRKNHVSNRELVLVLAFAIGLLASLAAYILHFIIKLIEELVTSGFDVATINWLYLIYPIVGIWLTSLFVKYVVRDNISHGITRVLYAISTKQSRLKAHNTWSSIVASAITIGFGGSVGAEAPIVLTGSAIGSNLGRIFNLDNRTLMLLVGCGATAAVSGIFKAPIAGLVFTLEVLMVDLTMASLLPILIASVTATCFSYFFTGGSSMFHFQMDNIWGLDRVPPTILLGIACGFVSLYFMRLMSWCENGYGKLSSKPYLKLLVGGLVLSPLIFLFPSLYGEGYDSLRLFIEGKTEADWMQIMSGSMFAEKSNFLLLYVGLVVMTKVFATSATNGAGGCGGTFAPSLFIGGFGGFFFARFWNMEQLGVYIPEKNFTLYGMAAVMSAVMHAPLTGIFLIAELTGGYQLFIPLIIVTISSYLTINIFEHHSIYAVRLAKQGKLLTHHTDKSILTLMSMDKIIDHDFTSVEPDMEMGKLIHAISSSRNDYIPVLDESRKLLGEIDINNLRHIIFRTELYHRFHVNQLMSPPAAMLGVNDPMEDVMKTFERTGAQYLPVVNIDSQLVGYISRARLYSMYRQFVADFSAE
>NZ_CP054011.1|WP_004361264.1|752593_753163_-|threonylcarbamoyl-AMP-synthase
MKQEDDIKKAIEVMRKGGIILYPTDTVWGIGCDATNAEAVAKVYALKRRDDSKALICLVDSDNRLQRYVRNVPDVAWQLIEAVEKPTTLILDGAVNLAPNLIAEDGSIGIRITKEPFSHELCYRFQKAIVSTSANVSGEPAAQNYRDISQEILDGVDYVCESRRQEHKPHTPSSIIKLAADGEVKVIRK
>NZ_CP054011.1|WP_036886809.1|753766_754768_-|ROK-family-protein
MDVTEQKPVVTGLEKPFVIGLDLGGTNAVFGVVDQRGQVLATNSIKTQAYKTVDDFVEAGVEAIRPLVAKYGGIGQFRAMGIGAPNGNFYRGTIEFAPNLSWGHDGVVPLGEMFSKKLGIPVGLTNDANAAAIGEMQYGVARGLKDFIMITLGTGVGSGIVINGQMVYGSDGFAGELGHIIMVRGEKGRTCGCGRRGCLETYCSATGVARTAREFLQNSKEDSLLREMKPEDITSLDVSIAAGRGDALAKRVYEFTGNMLGEACADFATFSSPEAFIFFGGLTKAGDLLMEPIMRSYKEHALEIFKDKPKFLVSSLDDAAAAVLGASAIGWEL
>NZ_CP054011.1|WP_004361268.1|754899_755586_+|LysE-family-transporter
MQFPIQLDILDFIFKGLLIGIIASAPMGPVGILCIQRTLNKGRWYGFITGIGAAISDTIYALIVGLGMSFIMGPLENPTYKLIVQITGSVLLLLFGIYCFKSDPMKKAHQSGKEKGSLFHNGVTAFLVTLSNPMIIFLFIASYAQFAFVQPNRPLEMIIGFACIPAGALLWWYGLSWLIDKIRGKFDVNGILIINKVIGSVVILFSIIMLVGTVFNLYHLPTIDGLME
>NZ_CP054011.1|WP_004361270.1|755595_756204_+|DUF4924-family-protein
MFVAKELRKKSIAEYLLYMWQIEDTIRAYGCSLTRIRKEYIDQFQYTEEQKEEEEDWFGDLVRMMNQEGCREGGHLQINKVLMQDLTELHAQLLQSSKFPFYSAEYYRVLPFIVELRGKTKRTADKMARTNDERLKSVAAQLGKSEIETCFDLLYGVMMLRLQKKEITPETTRALNEITTFIGMLSDYYIKDKTEGLNFGEE
>NZ_CP054011.1|WP_004361272.1|756216_757101_+|dTDP-4-dehydrorhamnose-reductase
MNILVTGANGQLGNEIQLVSKQSKDHYIFTDVCEGYTKLDITNLEDIRKMVQDNKIECIINCAAWTNVDKAETAGEIVELLNATAPENLAKAMKEVGGLLVHVSTDYVFGGDPYNTPCKEDMKGTPTGVYGLTKLHGEEKIQATGVNHIILRTAWLYSEFGHNFVKTMMNLTATKPQLKVVFDQCGTPTYAGDLADAIFDIVENRKYEGNSGIYHFSNEGVCSWYDFTIKIAELAGNTACDIQPCHSDEFPSPVTRPAYSVLDKTKIKETFGIKIPYWVDSLKKCMKGLQEQDK
>NZ_CP054011.1|WP_004361274.1|757230_758799_+|peptide-chain-release-factor-3
MNEIERRRTFAIISHPDAGKTTLTEKFLLFGGQIQVAGAVKSNKIRKTATSDWMDIEKQRGISVSTSVMEFDYKDYKVNILDTPGHQDFAEDTYRTLTAVDSAIIVVDSAKGVEAQTRKLMEVCRMRNTPVIIFINKMDREGRNPFEVLDELEEELKISVRPLSWPIGQGQRFKGVYNIYEQQLNLFTPNKQRVTEKVEVDINSNDLDEQVGADFAEQLRNDLELVNGVYPDFDVEAYRRAEVAPVFFGSALNNFGVQELLDCFVEIAPSPRPTKAEERMVEPSEPKFTGFIFKITANIDPNHRSCIAFCKVCSGKFQRNQPYLHIRNGKTMRFSSPTQFMAQRKSTVEEAYPGDIVGLPDSGGVFKIGDTLTEGENIHFRGLPSFSPELFKYIENDDPMKSKQFQKGIEQLMNEGVAQSFVNQFNNRRIVGTVGQLQFEVIQYRLEHEYNAKCRWEPVHLYKACWIEADDEKELENFKKRKYQYMAKDIEGRDVFLADSGYVLSMAQQDFENIRFHFTSEF
>NZ_CP054011.1|WP_004361279.1|760566_761052_+|hypothetical-protein
MKINQLSFLLFTAVLLFSCGKTILPSDDDNEDETEKHSPSHSPNEAKIYTVSEFIKGDFGNNGVWVHGYIVGACKRSIKQAEWEAPFTFDSAILLADDPEEAEPENVISIQMVNKQMKEEIGLAANPQNYGKHIAFFGIKQKYLGIPGMKKHILASEWLDE
>NZ_CP054011.1|WP_004361282.1|761172_761769_+|sigma-70-family-RNA-polymerase-sigma-factor
MKNLNEMTDEQLALSYIEGSNDAFDLLLSRNQSKLFSYILFVVRDRDAADDLFQETFVKIITKLQQGRYSPTGKFSAWIMRIAHNVIMDWYRAQRADKVIDAPKDNDLSNVGGDDTVIDNIECQFINSQTLSDVKRMMNLLPATQREVVFMRFYQEMSFKEIAETTGVSINTSLGRMRYAIFNLRRMVREHKVSLQLT

Crispr_ID: NZ_CP054011_2

• CRISPR_ID: NZ_CP054011_2
• CRISPR_location: 1056556-1056652
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_2

Consensus_repeat	Method
CTAATTAGGCTAATAAGCCCAATAAACC	CRISPRCasFinder

spacers of NZ_CP054011_2

>2.1|1056584|41|NZ_CP054011|CRISPRCasFinder
CAATAAACCATAGAACAAATAGTGACTACAAAACAATATCA

CRISPR arrays and Neighbor proteins around NZ_CP054011_2

CRISPR arrays

The CRISPR arrays of NZ_CP054011_2

>merge|NZ_CP054011|2|1056556-1056652|CRISPRCasFinder
CTTATTGGCCTAATTAGGCTAATAAGCCCAATAAACCATAGAACAAATAGTGACTACAAAACAATATCACCTATTAGGCTAATTAGGCCAATAAGCC

>NZ_CP054011|2|2|1056556-1056652|CRISPRCasFinder
CTTATTGGCCTAATTAGGCTAATAAGCC	CAATAAACCATAGAACAAATAGTGACTACAAAACAATATCA
CCTATTAGGCTAATTAGGCCAATAAGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004361351.1|1050201_1051938_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NZ_CP054011.1|WP_004361343.1|1044397_1045969_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004361349.1|1049055_1050051_-|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl|CDD|223318
NZ_CP054011.1|WP_004361344.1|1045992_1046205_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_172891370.1|1057965_1058382_+|four-helix-bundle-protein	unknown	unknown	gnl|CDD|275085
NZ_CP054011.1|WP_004361378.1|1068008_1068875_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|366491
NZ_CP054011.1|WP_004361353.1|1052368_1052785_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|224961
NZ_CP054011.1|WP_004361347.1|1047693_1049049_-|glucose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|184504
NZ_CP054011.1|WP_036886839.1|1062155_1064045_+|DUF349-domain-containing-protein	unknown	unknown	gnl|CDD|377186
NZ_CP054011.1|WP_004361365.1|1059497_1060529_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341285
NZ_CP054011.1|WP_004361372.1|1064785_1065172_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NZ_CP054011.1|WP_004361374.1|1065555_1065915_+|ribosome-silencing-factor	unknown	unknown	gnl|CDD|376779
NZ_CP054011.1|WP_172891369.1|1056896_1057814_-|IS982-family-transposase	unknown	unknown	gnl|CDD|372648
NZ_CP054011.1|WP_004361357.1|1053926_1055588_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl|CDD|272941
NZ_CP054011.1|WP_004361345.1|1046746_1047481_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319829
NZ_CP054011.1|WP_004361376.1|1065963_1067994_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NZ_CP054011.1|WP_004361355.1|1052785_1053832_+|isochorismate-synthase	unknown	unknown	gnl|CDD|273127
NZ_CP054011.1|WP_004361368.1|1061070_1061997_+|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl|CDD|213361
NZ_CP054011.1|WP_004361359.1|1055715_1056543_+|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl|CDD|180958
NZ_CP054011.1|WP_004361363.1|1058392_1059430_+|o-succinylbenzoate-synthase	unknown	unknown	gnl|CDD|239436

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004361351.1|1050201_1051938_-|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_CP054011.1|WP_004361349.1|1049055_1050051_-|NAD(P)-binding-domain-containing-protein	gnl|CDD|223318	COG0240, GpsA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	2.89526e-88
NZ_CP054011.1|WP_172891370.1|1057965_1058382_+|four-helix-bundle-protein	gnl|CDD|275085	TIGR04258, hypothetical_protein, four helix bundle suffix domain. This domain occurs as a suffix domain to some members of the much broader protein family TIGR02436, a few of whose other members are encoded within intervening sequences of bacterial 23S ribosomal RNA. Some proteins with this domain, in turn, are followed by a predicted DNA topoisomerase type C4 zinc finger.	1.34242e-17
NZ_CP054011.1|WP_004361378.1|1068008_1068875_+|phosphatidate-cytidylyltransferase	gnl|CDD|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	1.68953e-45
NZ_CP054011.1|WP_004361353.1|1052368_1052785_+|PaaI-family-thioesterase	gnl|CDD|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	1.83338e-22
NZ_CP054011.1|WP_004361347.1|1047693_1049049_-|glucose-6-phosphate-isomerase	gnl|CDD|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_CP054011.1|WP_036886839.1|1062155_1064045_+|DUF349-domain-containing-protein	gnl|CDD|377186	pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins. There are two or three alpha-helices, and possibly a beta-strand.	4.16022e-18
NZ_CP054011.1|WP_004361365.1|1059497_1060529_+|AMP-binding-protein	gnl|CDD|341285	cd17630, OSB_MenE-like, O-succinylbenzoic acid-CoA ligase. This family contains O-succinylbenzoyl-CoA (OSB-CoA) synthetase (also known as O-succinylbenzoic acid CoA ligase) that belongs to the ANL superfamily and catalyzes the ligation of CoA to o-succinylbenzoate (OSB). It includes MenE in the bacterial menaquinone biosynthesis pathway which is a promising target for the development of novel antibacterial agents. MenE catalyzes CoA ligation via an acyl-adenylate intermediate; tight-binding inhibitors of MenE based on stable acyl-sulfonyladenosine analogs of this intermediate provide a pathway toward the development of optimized MenE inhibitors.	1.45182e-59
NZ_CP054011.1|WP_004361372.1|1064785_1065172_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	6.7722e-28
NZ_CP054011.1|WP_004361374.1|1065555_1065915_+|ribosome-silencing-factor	gnl|CDD|376779	pfam02410, RsfS, Ribosomal silencing factor during starvation. This family is expressed by almost all bacterial and eukaryotic genomes but not by archaea. Its function is to down-regulate protein synthesis under conditions of nutrient shortage, and it does this by binding to protein L14 of the large ribosomal subunit, thus acting as a ribosomal silencing factor (RsfS) by blocking the joining of the ribosomal subunits. This family is structurally homologous to nucleotidyltransferases.	8.31996e-40
NZ_CP054011.1|WP_172891369.1|1056896_1057814_-|IS982-family-transposase	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.15694e-90
NZ_CP054011.1|WP_004361357.1|1053926_1055588_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl|CDD|272941	TIGR00173, menD, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase. MenD was thought until recently to act as SHCHC synthase, but has recently been shown to act instead as SEPHCHC synthase. Conversion of SEPHCHC into SHCHC and pyruvate may occur spontaneously but is catalyzed efficiently, at least in some organisms, by MenH (see TIGR03695). 2-oxoglutarate decarboxylase/SHCHC synthase (menD) is a thiamine pyrophosphate enzyme involved in menaquinone biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	2.55882e-108
NZ_CP054011.1|WP_004361345.1|1046746_1047481_-|HAD-IA-family-hydrolase	gnl|CDD|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.85255e-44
NZ_CP054011.1|WP_004361376.1|1065963_1067994_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP054011.1|WP_004361355.1|1052785_1053832_+|isochorismate-synthase	gnl|CDD|273127	TIGR00543, Salicylate_biosynthesis_isochorismate_synthase, isochorismate synthases. This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.24389e-68
NZ_CP054011.1|WP_004361368.1|1061070_1061997_+|magnesium-transporter-CorA-family-protein	gnl|CDD|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	5.36463e-106
NZ_CP054011.1|WP_004361359.1|1055715_1056543_+|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl|CDD|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
NZ_CP054011.1|WP_004361363.1|1058392_1059430_+|o-succinylbenzoate-synthase	gnl|CDD|239436	cd03320, OSBS, o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway. Menaquinone is an essential cofactor for anaerobic growth in eubacteria and some archaea. OSBS belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	1.20164e-74

Protein sequences

>NZ_CP054011.1|WP_004361359.1|1055715_1056543_+|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MEKREWKPIEGFNFEEILFEEYNHIAKVTINRPRYRNAFTPKTVWEMSQAFNYCREAIDIRVVILTGAGDKAFCSGGDMHVKGHGGYIGTDGIPRLNVLDLQMQIRRLPKPVIAMVNGYAIGGGHVLHVVCDLSIASDNAIFGQTGPKVGSFDAGFGASYLARVVGQKKAREIWFLCRQYSAVEAERMGLVNKVVPFDRLEDECIEWAETMIERSPLALRMMKAGFNAELDGQAGIQELAGDATMLYYTLDEAQEGAKAFLEKRKPDFDKYPQFP
>NZ_CP054011.1|WP_004361357.1|1053926_1055588_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MYSNKENVNILTALLVKKKITKAVVCPGSRNSPIVHNLCACPEIECYPVTDERSAGFVALGMTLADNEPVAVCVTSGSALLNLAPAVAEAFYQKRPLIIISADRPAQWIDQQDGQTLQQHRALEPNVRKSVTLPEPHNEEERWYCNRLVNEALNAVRMNDGSPVHINVPISEPLFEYNVPQLPDERNIFLMYAATNEVCVYEMAADFFRGKKLMVVLGQLTPEVVGNSLEAIEALKKVAVVLQEKLADDDIGPAQPIDEVLKMIGEDESYRPDHLIYIGGTIVSKRLRQFLRKCECKMSIVVNGIDEFCDTFMHTTDMIQGLPEDVIGIFANETEGVKKSDFVTLWDKAFDKALAIRKTFKPRFSQMLAVKAFHEKMREEAVDGELFYGNSSAVRLGNIFSDQYIYVNRGVNGIEGSLSTAVGYAIAHQEEDDVYCVIGDLSFFYDQNALWNESLPPNLSILLLNNGGGGIFRQLPGLERSPYRDSAIAAQHTTTAEGICQTHDIVYLSARNEEELYKNLDKLFNSEEGPVLLEVFTNAEEDTQALKDYYQVF
>NZ_CP054011.1|WP_004361355.1|1052785_1053832_+|isochorismate-synthase
MDSFFIYREPFEKVCHCYSQPEKPTAISSLTELNGRKGFVIAPFYCDDSKSLYLLDGQKGCSITLPLDGSKGFDAIPDWQDEAVLTNETPSLREAYHNDFCRFHKELEHNRFRKLVLARSIVETKDERATPRSIFLKACEKYPRSYISLFYTAETGMWLIASPEILLRGDAEGYQTMALAGTMKYEGEDMKWSTKNQEEQQLVADYIRACLQPFAAEITESKPYTTRAAHLAHLRTDFTFRLKDTQRVGTFLTAFHPTPAVCGMPKDEAQQFILHNEQLNRSYYSGFSGLLGEKGAAKLYVTLRCMQLSRSTCRLYAGGGLLKESIEENEWQETEAKLDTMRQLLNHN
>NZ_CP054011.1|WP_004361353.1|1052368_1052785_+|PaaI-family-thioesterase
MNVENIIKSIHQEDGLSRTLGMEFISTPEDDTLKARMAVDDRNKQPFGFLAGGASLALAENLAGVGSMALCPGKMAMGINVHGNHVKAMPYGGTVTAYGKLIHRGHTLHVWNIDIKNGEDELISSVQVTNYVIAPQEK
>NZ_CP054011.1|WP_004361351.1|1050201_1051938_-|lysine--tRNA-ligase
MNVLELSEQEIGRRQSLQELREMGIDPYPAAEFPTNAYSTDIKEQFKEDEQREVVIAGRMMGRRVMGKASFAELQDSKGRIQVYITRDDICPGEDKEFYNKVFKKLLDIGDFIGVKGEVFKTQMGEISVHAKEITVLSKSLKPLPVVKYKDGEAYDKFEDPEQRYRQRYVDLVVNEGVKDTFLKRAIVLRTMRKFFDEAGYTEVETPTLQSIAGGASARPFITHFNALNVDMYMRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRFHNPEFTCMELYVQYKDYNWMMSFTEKLLEKICIEVNGKPEVQVGDKVISFKAPFRRLPILDAIKEKTGFDLYGKTEEEIRNIAVNELKLEEIDESFGKGKLIDEIFGEFCEGTYIQPTFITDYPVEMSPLTKMHRSKPGLTERFELMVNGKELANAYSELNDPIDQEERFIEQMRLADKGDDEAMIIDQDFLRSLQYGMPPTSGIGIGIDRLVMLMTGKEYIQEVLLFPQMKPEPKIPQSSVKEWAELGVAEEWVYVLRKAGFNLISDIREEKAQGLQQKLGEINKKYKLGYEKPSVEAIQQWIDGANEK
>NZ_CP054011.1|WP_004361349.1|1049055_1050051_-|NAD(P)-binding-domain-containing-protein
MFDIGKIAIIGSGSWATAIAKIVVEHTHHIGWYFRRDDKIEEFKRRGHNPSYLTSVKFNMNEVMLSSDINKIVQEYDTLVFVTPSPYLKALLKKLKTKLHTKLILTAIKGIVPDENLVCSEYFHEAYGVPYDNLAVIGGPSHAEEVAMERLTYLTVGCSDLEKARAFTEVLASNYVKTKTSPDVLGIEYASVLKNVYAISAGICSGLKYGDNFQAVLMSNAMQEMERFLNTINPIQRSIIDSVYLGDQLVTGYSKFSRNHTFGTMIGKGYSVKSAQIEMEMVAEGYFGTKCMKEINRRLHVNMPILDAVYNILYERISPQIEIKLLTDSFR
>NZ_CP054011.1|WP_004361347.1|1047693_1049049_-|glucose-6-phosphate-isomerase
MESIKLDITKAAQFLNPGAVEAYAPQVAAAQDALEKATCPGNDFLGWLHLPSSITPAFLNEIQAVANTLREKCEVVVVAGIGGSYLGARAVIEALGNSFAWLVNDKKNPTILFAGNNIGEDYLAELTDYLKDKKFGVINISKSGTTTETALAFRLLKKQCEDQLGKEAAKDVIVAITDEHKGAARAAATKEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGFDVQKLVEGAQVMEKETSADVPFANNIAARYAAVRQGLYSEAGKKIEIVANFQPKLHFFAEWWKQLYGESEGKDRKGIFPAACDFTTDLHSMGQWIQEGERSIFETVISVEEPNAKVLFPHDEENLDGLNFLAGKRVDEVNKMAELGTRLAHVDGGVPNIRVSVPTLNEYYLGQLIYFFEKACGISGLIQEVNPFNQPGVEAYKKNMFALLNKPGYEAESKAIQERLTKE
>NZ_CP054011.1|WP_004361345.1|1046746_1047481_-|HAD-IA-family-hydrolase
MSSQSQQNIQSVEGTRRNPKVVLFDMDGVLYDSMPNHGVAWQRAMKEFGIHFTLEDSYATEGARGVDTIRKYAKEQLGKELTEEEAQKVYDVKAHYFHEMPEAKVFDGVIDLMQKIKASGLKIGIVTGSAQLPLIKRVTRDFGDYVSADQITTAYDVKRGKPNPDPYLMGLQKAGNYLPTEGIVVENAPLGVHAGAAAGCYTVAINSGPLDDSVLLNEGADILFPTIREFADYWKLFLNSFFKY
>NZ_CP054011.1|WP_004361344.1|1045992_1046205_-|hypothetical-protein
MNKKQEKAYIKPLTTLVDVIENECIMAASGTTAEGGHVSAGDDETLHAKGFNFFSDEEDNYTSETTEKRK
>NZ_CP054011.1|WP_004361343.1|1044397_1045969_-|hypothetical-protein
MKMKCQYLWALPVLALFTLASCSNDDTAQENNGKQKGTPAGMTEFAVKEATTRTMGVYSGLGIDFYWTQGDKLWINNTSSLVQSSDDDITGKAATAKFYFTGTYNASSYPVRYTGKGSNAGDKVTIKAEQKQATPNDGSHIGTDGDCGTATATRGADGKYGFTLSHKASYITFMPYYSYEFAEDVKVTQIKVTADEVLAGEFKFDDNGLDLASRTTVVNPGKSITLELNGGTNNGFTIPISPDYTKNAAIMVLAPGTYHNFTVEYRLYDQKTLVYGTVSKNYGQLTFHAGQNKKVVADLQVPNYSKDRFYMWDAAVGQNAWKNYENYQPILNEGVDSHYPTVSTDARWYNPALIPAKASRSAKDCPNANEMLWYCMYGDPHWDSSIWSTMKHLYDGGMWLKKRSVIAADQHKTLQQLKDAAPGGTDYTKAYPLSFKIYDLYVKDNMSVILGKPTNSSDYIFLPTTGFYHAGDGKLQRVGNRGYYWSSTPRQDGGLNAYNLYVQRDRVHVGYGDRTNAHCLWPE
>NZ_CP054011.1|WP_172891369.1|1056896_1057814_-|IS982-family-transposase
MITKDKITEIFCIADDFCKEFELETDKIGLSEKSKGCHRHRKWRMSKSEIITILICFHFNSYRNFRHYYTFFVKEHLADLFPNQLSYNRFLELEARVSVEMMMFLQICCFGRCTGISFIDSTCIPVCHNKRICRNKVFRNYATRGKSTMGWYFGFKLHLICNERGEILNFMLTKANVDDRDENVFNRLTDNVFGKLFADKGYISQGLFERLFNDGINLVTGIRSNMKNKLMPLYDRLLLRKRSVIETINDELKNVAQLVHSRHRSIFNFAMNVLSAIAAYCFFEKKPAVNIDFAIEQHSGQLTLF
>NZ_CP054011.1|WP_172891370.1|1057965_1058382_+|four-helix-bundle-protein
MVQAARSGKQNIAEGCAASTTSAETEIKLVNVARASLQELLIDYEDYLRVRDLTKWEINDRRAIVARHVCAKHNESSFYRNAIQVRTDETIANIAITLIYQEDVILRKYLDHIKEDFIKHGGIREQMTRARIEYRNKQ
>NZ_CP054011.1|WP_004361363.1|1058392_1059430_+|o-succinylbenzoate-synthase
MYKINISSRTLHFLLPAGTSRGVYTTRKSYYVTLSDTNQLDVVGIGECATLPDLSYDAMTDEEYEQKLRSFCDDFCHTGVIDIDAMRPYPSMLFGLETAKAQLDAKGSINFFNTAFGRGEEGITINGLVWMGTFDEMYQRLETKLKAGFHCVKLKIGAIDFEKELDLIRHIRQTFTREQVELRVDANGAFAPEDAMQRLETLAQYDIHSIEQPIRQHQWQEMARLCADSPLPIALDEELIGVNNPAEKVLLLDTIRPQYIILKPSLHGGMTGTKEWITIARERNIDSWITSALESNIGLNAIAQLTADIYGPNITTPQGLGTGQLFTDNIPMPLEIRGDQLWISD
>NZ_CP054011.1|WP_004361365.1|1059497_1060529_+|AMP-binding-protein
MTLQDFLSEWHNDNPQLLVHTSGSTGKPKPLWVEKQRMLNSAHITCDFLGLKAGDTALLCMPLDYIAGKMVVVRSIERNLRLLNVTPSGHPLSDHSLSEAGIPNEEITFAAMVPLQVYNSLQVPKERERLRRIHHLIIGGGAVDDKLSAALQDFPNAVWSTYGMTETLSHIALRRLNGPDASEWYKPFDGVKVWLNEEGCLVIDAPAVCAHPLVTNDRAEIRTTDTKEGLNTPYFRILGRKDNVIDSGGIKIQIEEVEHLLKSSLTADFAITSCPDERFGEAVVLLTTQDDTDSIKTLCQQCLPKFWQPRFIFHVPSLPQTGNGKPARAEIKALARQLCNSKA
>NZ_CP054011.1|WP_004361368.1|1061070_1061997_+|magnesium-transporter-CorA-family-protein
MKTYWNINGTLNTIKEWQPNCWIQVTCPTEQDQQELEDTFHIPDYFLSDISDTDERARYEYDDGWMLIILRIPYVKEIRSRTPYTTVPLGIIHKKDVTITVCNFETNMMLDFVSYQQKRNEGFTDYVDLIFRLFLSSAVWYLKRLKQINTLIEKAKRNLDKGVDNESLIGLSRLQDSLTYFITSIRGNENLLAKLKFKLQIDELDADLIEDVNIEMSQARETTSIYSDILESTMDTYSSIINNNMNTVMRTLTSVSIVMMLPTLISSLFGMNLVNGMETNPWGFPVAMFLSVVVSAASWWLLRRKRLL
>NZ_CP054011.1|WP_036886839.1|1062155_1064045_+|DUF349-domain-containing-protein
MMDSQENALNQGTEEVKLSEEVAANATTENSEVQNVNTDAVEENLNQPVETKSESEKENLAAKTYSSKKEIIERLKAIVDSNETPEKAEVEHLKTVFYKLHFVEREAQQKAYLENGGDPEKYQVLPDEDEEIFKAEMTIIKEKRQKAFLALEEEKQQNLKKKETIIEQIKAMATTPEEANKNFDQFKKLQHEWKEIKMVPAEKANELWRNYQLYVEQFYDLLNLNREAREYDFKKNLEKKTKLCEAAEKLAEETDVISAFHQLQELHQEYRETGPVAKELREQIWARFKAASTVINKRHQQHFETLRTREEENLTKKTALCEKAEELAKQENKSSADWEKRTKEIIAIQQEWKTIGFAPQKMNVKIFERFRAACDDFFGRKGEFFKQLKEQFAENTEKKKALVEKAQALSESTDWKATSDKLIALQKEWKTIGMVPKKIGDQLWNDFLAACNRFFEARNAVHADSRNEEHENLNKKRDIISQLKELVEQTGENLQEKVQKLTEQYNKVGHVPYKEKDKLYKEYHEVLDKIYKDLHISAARKRVDNFRNNLKKVADRGVDALDNERGRLLRRFEQLKQEVNTYENNLGFLNISSKKGNSLIDEMNRRIQKLKDDMDEVKQKIKAIDAENK
>NZ_CP054011.1|WP_004361372.1|1064785_1065172_-|rhodanese-like-domain-containing-protein
MKKLFTAILAVLGIGMGACAQNLYEDVDVNRFEQIIKSDSVQLVDVRKLDEFTEGHIPGAIHIDVLTPSFLSNALAKLDKKRPCAVYCRSGKRSAIAATLLAKEGYTVTNLLGGIIAWTEAKKKTVKE
>NZ_CP054011.1|WP_004361374.1|1065555_1065915_+|ribosome-silencing-factor
MDKTKNLVELITKGIQDKKGHGIVIADLSEIDGTICRYFVICQGNSTQQVEAIAGSVSDYVRETIGEKPINCVGLGNAQWVAIDYADVIVHIFTPETREFYDIEHLWEDAKLTTLPDLD
>NZ_CP054011.1|WP_004361376.1|1065963_1067994_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MDNSNPKNKPNMPKFNMNWLYIFVIIALGVVFFAGGNGLFPSSAGIDKDYTTFKQYVAKGYATKVIVNRNDNTLRMYVSPNHIRDIFKKGTQEVGTAPYVTVEIGSVDKVETFLDQAVAQKKIVSYSYENKTSNTILDILGSIAPWIFFFGIWYFLMRRMGGGASGGGGVFSVGKSKAKLYEKANEMGITFKDVAGQTGAKQEVQEIVEFLKNPKKYTDLGGKIPKGALLVGPPGTGKTLLAKAVAGEAGVPFFSMSGSDFVEMFVGVGASRVRDVFHQAKEKSPCIIFIDEIDAVGRARSKNPAMGGNDERENTLNALLTEMDGFGTNSGVIVLAATNRVDMLDKALLRAGRFDRQIHVDLPDLPERKEIFLVHMRNLKLEKNLDIDLLARQTPGFSGADIANVCNEAALIAARHNSKEVTKQDFLDAVDRIIGGLEKKTKIMTADEKRTIALHEAGHATISWFCEHANPLVKVSIVPRGQALGAAWYLPEERPITTKEQMLDEMCSLLGGRAAEELFTGHISTGAMNDLERATKSAYGMIAYAGMSDKLPNICYYNNDEYNFQKPYSDTTAKTIDEEVLKMINSQYERAKQILTEHKEGHNRLAQILIEREVIMAEDVEEIFGKRPWVSRTQELLEQEEKSQPKLEDMPEEVKQAQAEHEARIAKEGSDNASDL
>NZ_CP054011.1|WP_004361378.1|1068008_1068875_+|phosphatidate-cytidylyltransferase
MSDKLKNLIVRAVTGVFFVTVMVLGILHPHALIALFAFITGLSIWEYTGLVNNIKGVRVNRFISTIAGVYFFLSVAGLRLTPVEGFVIFVPYILTILYLLVSELYLKNENPINSWAYTMLGQMYIALPFSMINVLAFQQGEMGQITFDFLLPLSIFIFLWTNDTGAYLCGSLFGKHKLFPRISPKKSWEGSIGGGILVLIVAGVIGYFANIGATPHMLSIPAWVGLGLVVVVFGTWGDLVESLLKRTLGVKDSGNMLPGHGGMLDRFDSSLLAIPAAVVYLYTLTFFY

Crispr_ID: NZ_CP054011_3

• CRISPR_ID: NZ_CP054011_3
• CRISPR_location: 1184022-1184117
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_3

Consensus_repeat	Method
TCTGACCTTATGTCATTATGGCT	CRISPRCasFinder

spacers of NZ_CP054011_3

>3.1|1184045|50|NZ_CP054011|CRISPRCasFinder
GTCATTAAGTCTACCACAGAATAAGTTAAACTCTTACTTTGTCTTTTCCC

CRISPR arrays and Neighbor proteins around NZ_CP054011_3

CRISPR arrays

The CRISPR arrays of NZ_CP054011_3

>merge|NZ_CP054011|3|1184022-1184117|CRISPRCasFinder
TCTGACCTTATGTCATTATGGCTGTCATTAAGTCTACCACAGAATAAGTTAAACTCTTACTTTGTCTTTTCCCTCTGACCTTATGTCATTATGTCT

>NZ_CP054011|3|3|1184022-1184117|CRISPRCasFinder
TCTGACCTTATGTCATTATGGCT	GTCATTAAGTCTACCACAGAATAAGTTAAACTCTTACTTTGTCTTTTCCC
TCTGACCTTATGTCATTATGTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_081445991.1|1172364_1172652_+|DUF1016-family-protein	unknown	unknown	gnl|CDD|380007
NZ_CP054011.1|WP_004360730.1|1180892_1181183_-|hypothetical-protein	unknown	unknown	gnl|CDD|367565
NZ_CP054011.1|WP_036886560.1|1179926_1180886_-|Fic-family-protein	unknown	unknown	gnl|CDD|225095
NZ_CP054011.1|WP_004360729.1|1181197_1182277_-|Fic-family-protein	unknown	unknown	gnl|CDD|225095
NZ_CP054011.1|WP_004360733.1|1176089_1177391_+|alpha-L-fucosidase	unknown	unknown	gnl|CDD|376461
NZ_CP054011.1|WP_004360726.1|1185312_1186557_-|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl|CDD|379536
NZ_CP054011.1|WP_004360736.1|1172989_1173937_-|cysteine-synthase-A	unknown	unknown	gnl|CDD|273463
NZ_CP054011.1|WP_004360724.1|1187704_1189609_-|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|234715
NZ_CP054011.1|WP_004360718.1|1196878_1197961_-|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NZ_CP054011.1|WP_004360723.1|1189910_1190477_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360728.1|1182615_1183833_-|DUF3874-domain-containing-protein	unknown	unknown	gnl|CDD|372421
NZ_CP054011.1|WP_004360734.1|1174968_1175982_+|DUF4435-domain-containing-protein	unknown	unknown	gnl|CDD|373095
NZ_CP054011.1|WP_004360721.1|1191844_1193302_-|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|223246
NZ_CP054011.1|WP_004360722.1|1190807_1191425_-|DUF4840-domain-containing-protein	unknown	unknown	gnl|CDD|374380
NZ_CP054011.1|WP_004360720.1|1193304_1194645_-|Trk-system-potassium-transporter-TrkA	unknown	unknown	gnl|CDD|236541
NZ_CP054011.1|WP_036886559.1|1184364_1184739_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360725.1|1186839_1187637_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360735.1|1174130_1174949_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379114
NZ_CP054011.1|WP_004360719.1|1194687_1196607_-|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|235470
NZ_CP054011.1|WP_036886561.1|1177599_1179810_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|372509

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_081445991.1|1172364_1172652_+|DUF1016-family-protein	gnl|CDD|380007	pfam17761, DUF1016_N, DUF1016 N-terminal domain. This family may include an HTH domain.	1.72891e-12
NZ_CP054011.1|WP_004360730.1|1180892_1181183_-|hypothetical-protein	gnl|CDD|367565	pfam03568, Peptidase_C50, Peptidase family C50.	0.00809473
NZ_CP054011.1|WP_036886560.1|1179926_1180886_-|Fic-family-protein	gnl|CDD|225095	COG2184, Fic, Protein involved in cell division [Cell division and chromosome partitioning].	3.03082e-40
NZ_CP054011.1|WP_004360729.1|1181197_1182277_-|Fic-family-protein	gnl|CDD|225095	COG2184, Fic, Protein involved in cell division [Cell division and chromosome partitioning].	7.50157e-20
NZ_CP054011.1|WP_004360733.1|1176089_1177391_+|alpha-L-fucosidase	gnl|CDD|376461	pfam01120, Alpha_L_fucos, Alpha-L-fucosidase.	1.01617e-134
NZ_CP054011.1|WP_004360726.1|1185312_1186557_-|PD-(D/E)XK-nuclease-family-protein	gnl|CDD|379536	pfam14281, PDDEXK_4, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	7.04622e-37
NZ_CP054011.1|WP_004360736.1|1172989_1173937_-|cysteine-synthase-A	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	7.13495e-165
NZ_CP054011.1|WP_004360724.1|1187704_1189609_-|molecular-chaperone-DnaK	gnl|CDD|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP054011.1|WP_004360718.1|1196878_1197961_-|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	2.11604e-12
NZ_CP054011.1|WP_004360728.1|1182615_1183833_-|DUF3874-domain-containing-protein	gnl|CDD|372421	pfam12990, DUF3874, Domain of unknonw function from B. Theta Gene description (DUF3874). Based on Bacteroides thetaiotaomicron gene BT_4228, a putative uncharacterized protein As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or other bacterial species vs when in culture.	9.55945e-15
NZ_CP054011.1|WP_004360734.1|1174968_1175982_+|DUF4435-domain-containing-protein	gnl|CDD|373095	pfam14491, DUF4435, Protein of unknown function (DUF4435). This presumed domain is functionally uncharacterized. This domain is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 285 and 362 amino acids in length. This domain is sometimes associated with AAA domains.	4.683e-57
NZ_CP054011.1|WP_004360721.1|1191844_1193302_-|TrkH-family-potassium-uptake-protein	gnl|CDD|223246	COG0168, TrkG, Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	3.17517e-106
NZ_CP054011.1|WP_004360722.1|1190807_1191425_-|DUF4840-domain-containing-protein	gnl|CDD|374380	pfam16128, DUF4840, Domain of unknown function (DUF4840). This family consists of uncharacterized proteins around 220 residues in length and is mainly found in various Bacteroides species. The function of this family is unknown.	1.37118e-19
NZ_CP054011.1|WP_004360720.1|1193304_1194645_-|Trk-system-potassium-transporter-TrkA	gnl|CDD|236541	PRK09496, trkA, Trk system potassium transporter TrkA.	2.42527e-169
NZ_CP054011.1|WP_004360735.1|1174130_1174949_+|ATP-binding-protein	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	1.48031e-13
NZ_CP054011.1|WP_004360719.1|1194687_1196607_-|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|235470	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional.	0
NZ_CP054011.1|WP_036886561.1|1177599_1179810_-|AAA-family-ATPase	gnl|CDD|372509	pfam13166, AAA_13, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.	1.22866e-108

Protein sequences

>NZ_CP054011.1|WP_004360728.1|1182615_1183833_-|DUF3874-domain-containing-protein
MQYKNLKNIKAENQRNRQSERLKNDITRRLLNYLERKYEMRYNTALGCTEIRKAGSDESFMPADERMRNTIAIKARLDGIDAWDKDIRRYTESGFVKAFNPVDDFLKGLQGRWDGKNHIEALADCVPNDNARWAEWFHTWFLAMVAQWMGLDVSHGNSVAPLLISRQGYRKSTFCKRLLPEALQWGYNDNLIMSEKQNTLRAMSQSLLINIDEFNALSAKTQDGFLKNVMQLVSIKLRQPYRQQQLTLPRVASFIATANVSDVFSDPSGCRRFIAVTLTGPIRLPDHIDYEQLYAQAVAELDAGRRYWFDEADTQEIMANNVQYQQRTPAEALFFECFSIPKDLTKGAYMTAASIFSLLRQRYGSQLHLTSLSHFGRVLANIPNLHSKHSSHGTEYLVAVCSSLG
>NZ_CP054011.1|WP_004360729.1|1181197_1182277_-|Fic-family-protein
MITDFEEYIRQSEPHKREKGYAWQTAIGLQAVDGLKTSDYLRETARQHIEGDITIEEVKQLVNSYYESKSARKGGGNRTEEADKVSARITELLSEQSFTFSPLEYISIHRRLFEGIYEHAGKIRDYNITKKEWVLNGETVLYAGADSIRETLDYDFAREKEYDYKHHDIAEAVSHISQFVSDLWQIHPFGEGNTRTTAVFTIKYLRTFGFDISNETFANYSWYFRNALVRANYNNMPKGIFATTQYLEAFFRNLILGEQNELKNRLLHIEAPKHLVQSASLEVPKSHNDTLDCTLEEVALIKFVKEKPQATQKEIAVHIGKSERTVKRMTTRLSKRGIIERKNGKRNGYWEIKSKELNN
>NZ_CP054011.1|WP_004360730.1|1180892_1181183_-|hypothetical-protein
MKRYSLKIKEIELQLHDGNYNRRVQYNEKDFDILVISFKEKADLIRKFAISANCLPNSDSIHLIFDPNTHKVSFSPQEINTSIINDVEKLLCSDKT
>NZ_CP054011.1|WP_036886560.1|1179926_1180886_-|Fic-family-protein
MAEDKEQYKKSIRFFNDREVRAVWDEEHSKWWFSVLDIIAAINEQDDYQKTRNYWKYLKTKLRKENSQLVSATNQLKLKASDGKSYKTDTFDAEGVTLLAKHINNTKATSFLDWFLYSDNTIDGQSKKKAYQLFESGILQTAEPRSVKCLQQIHAYLFGGLYDFAGQIRTKNISKGGFTFANYMHFPATLQTIERMPETTFDEIMDKYVEMKIRANEHHVNSFTNGRVQPNLCNVAHPFMEGNGRSTRIWLDLMLKRSLKRCVDWSQINKNDYLAAMRESVSDNTHIKALVKPALTAKIDDREMFMKCIDYSYCYEQND
>NZ_CP054011.1|WP_036886561.1|1177599_1179810_-|AAA-family-ATPase
MIKSIKLKKEKSCYKGETILDTNNKNVVLIYGLNGTGKSTIASYLHSFPECSNFSDCSINPNLDMQIEEILVYNKQFIEETFYTENNIKGIFTLSKENKEAKTKIDSANKFLEQLYKQQKEAEEKRKKEDEQWNKKVEGFQNKIWEIKRQYSGGDRVLQYCLQGVQSSKENLFNHLLNMKKPTIEPTKTIEELKNEVNNLNKQDAVEIPRIPLMVFNGEPIEKYTIFGEVITGNKGSKVSELIDNLANADWVKDGLSYLNLNTNQCPFCQQGITSKIIEDLKGYFDKTYNDILQNLTDLKDKYKEEVENTQKIDTFDNISILNRFKKDYEIAFNKFMNVIRNNLLRMEEKCKSPGTKVVIESHQELLDRLNEIISNANKIIEEYNTKLQNKQQEIDHIKDTFWEIQRFKYDQTVSLYTTTLNSHKQAINEIEHEYKEYTTQIQEQKGIITSEQKNVINIDEAIENINALLLDLGITDFKIIKHEEEGLYRITRGDQTEEEIFKSLSEGEKMIISFLYFTEQCKGRKLANDAIKKRIIVIDDPVSSLSHIHVFNVGRLIKERFYPTFQRNNDGGLDIRTRCEQVFILTHSFYFFYEMTEMNREKRHASQTLIRLYKDRQGSHIKSMSYEEIQSDYQAYWSIIKNRDSAPALIANCMRNIIEYFFNFVEKRDLNNTFNSEKLKDIRFQAFNRYINRESHSLGQNIYDFKEFNYDNFLEAFRLLFEIEGYETHYKKMMK
>NZ_CP054011.1|WP_004360733.1|1176089_1177391_+|alpha-L-fucosidase
MKKTLLLILTLLTSYVGMAQETYHPTAENLKAREQFQDEKFGIFLHWGLYSMMGTTEWIMTNRDINYKEYPKLAKTFYPSEFDADAWVKAIKAAGAKYITITTRHHDGFSLFKTATSSYNSVDGTPFKRDIIREIADACKRHDIKLHLYYSHLDWGREDYPVGRTGTGTGRPKEKANWASYYKFMNTQLTELLTNYGKVGAIWFDGWWDHDSDAKPFDWQLEEQYALIHKLQPQCLIGNNHHQTPFAGEDIQIFERDLPGENKAGLSGQSISRLPLESCQTINEHWGYNITDTLYKSPKELIQMLVRAAGKNANLLLNIGPEPGGALPALALDRLQAIGEWLNKYGETIYGTRGGIVTPHEWGVSTQRGNKLYIHILNCMDSSLFIPTGNHKIKSATVFGTNKRVNFTKTGNGITLNFDTVPTDIDYIVELTL
>NZ_CP054011.1|WP_004360734.1|1174968_1175982_+|DUF4435-domain-containing-protein
MGKRLSDNLSSAYIDAANRLNGKRARRKIIAYVEAYDDIFFWRTVLSGFENEERYFEVMLPSRLNLTKGKRSVLMNLVSQNIGENMIACVDADYDYLLQGTTPLSDEVNNNPYVFHTYAYAIENLQCYAPSLHDVTVAVTLNDHSIFNFEEFLKLYSESIHPLFVWSIWHYRKGYHRKFTISDFNRVVELGNFSLKGAVESLQRLRHKVQMRVRQLQREHPNAKESYLKLKEELHALGVTPSTTYLYIQGHHLFDNIIVPVLKRVCDRLVREREDEINRNAVHDTQRRNELSSYGHSTEAIIPMLRRNVGYTNAAPFLRLKEDIRRFLNPPSGHSIE
>NZ_CP054011.1|WP_004360735.1|1174130_1174949_+|ATP-binding-protein
MQKYADYIEEIEIDSLWSGKKHIRWTLDRQVNILSGINGVGKSTILNKVVRSLSQGGEFPSHSLKGVRLKVSPNDARWIRYDIIRSFDRPLMNSDSISKINVDLVTELDWQLFQLQRKYLDYQVNIGNRIIETLQSGEADAAEKAQQISQPKKRFQDILDDLFTETGKKIIRSENEIKFSSLGEELAPYQLSSGEKQILVILLTVLVEDNEHYVLFMDEPEVSLHIEWQKRLIDLILELNPNVQIILTTHSPAVIMNGWIDRVTEVTDITDK
>NZ_CP054011.1|WP_004360736.1|1172989_1173937_-|cysteine-synthase-A
MAKVVNKLTELIGNTPLLALNKFSAERGLKTPVLAKVEYFNPGGSVKDRIALAMIEDAEAKGLLKPGATIIEPTSGNTGVGLALVSAVKGYKLILTMPETMSVERRNLVKAYGATVKLTSGKDGMKGAIKAAEELRDSIPGSIILQQFENQANPERHNLTTGPEIWRDTDGKVDVFVAGVGTGGTVSGIGRYLKEQNPDVKVIAVEPTSSPVLSGGESGPHKIQGIGAGFVPNTYNNKYVDEIFQVENDQAILAGRQLAQQEGLLVGISSGAAAFAATEIAKRPENAGKTIVTLLPDTGERYLSTVLYAFDEYPL
>NZ_CP054011.1|WP_081445991.1|1172364_1172652_+|DUF1016-family-protein
MESSYLLIDDYEIWKSRFPNLTWTHIFKVLRIDDETAMRWYLETASKEMWSVRTLDRHKPSYYKNNKGTSSPLSPEGKNGEEICLKCNNFSTPRF
>NZ_CP054011.1|WP_036886559.1|1184364_1184739_-|hypothetical-protein
MHDCILKEQCLRYYAAKTLSISQHSALTVLPSTRSGNSCKAFHAMETERLAWGFSHLFDDVKHSDYRSLRSTMESHFGSRFVYYRYHRGINKLSEGEQQWVDELFQRYGYAAPRVYDNYQTCWK
>NZ_CP054011.1|WP_004360726.1|1185312_1186557_-|PD-(D/E)XK-nuclease-family-protein
MEDIKELLHKIRRFIDEDEILKKEKSKRGEDFNVFKIMHVESDEVRTHSAMLAALMDPKGTHSCGTAFLELFCQQLQNFVCDSKYSNFVFDSTNATVNFEKSIGGISRDKEEGGRMDILIESGTVQGDKSKAIIIENKIYASDQTKQLYRYYQFAKQKYGLENSLILYLTLDGHSPHDISVTGSSRKMKKNEDYFCISYRDFIRPWLQKCTEKAFDKPLVRETIIQYRNLLSLLTYQNMDEQKQKELIELLANSENIFTAIRIHDNYNRILNKVIGVELRKQVEEIANELRLELEFRTEDGYWQQQYSHFLLWKKEWNYAKICFEFKNANFNKLSYGIRYNSPKTREDNENIKQIIQEKIHDGRSEEWWAYIKDFEYNDWRREYVYRKLFNKDIQKEIKERVQDLMNLTEGITM
>NZ_CP054011.1|WP_004360725.1|1186839_1187637_-|hypothetical-protein
MKENKGGISKEDYINNFDEKKLEEAFQIALDTRKFEIELYWKRTGYFVLFIGAVFVGYYKVLPISGPSGSEKEWLLLLLSSLGFLLSLLWYMANRGSKFWQENWEAHIEDLSIKLRKPIFGIIKINEYTIYNPKQFNKSYPFSVSKVNQMVSLIITFSWLLILLKDLGVFLKFENNSSIVWDIAKVGVGVLDFILSYIILSSCRSFVTNVNIVESSDTSKNNKEKVYYFYNYDRTEIRQEDKLGVCNELQNITSFLRKICGIFKR
>NZ_CP054011.1|WP_004360724.1|1187704_1189609_-|molecular-chaperone-DnaK
MGKIIGIDLGTTNSCVAVFEGNEPVVIANSEGKRTTPSIVGFVEGGERKVGDPAKRQAITNPEKTIYSIKRFMGETYAQCQKEAERVPFKVVNEGGYPRVQIDDRKYTPQEISAMILQKMKKTAEDYLGQEVTDAVITVPAYFSDSQRQATKEAGQIAGLNVQRIVNEPTAAALAYGVDKANKDMKIAVFDLGGGTFDISILEFGGGVFEVLSTNGDTHLGGDDFDQVIIDWLADGFKAEEGIDLRKDPMAMQRLKEAAEKAKIELSSSSSTEINLPYITAEGGVPKHLVKTLTRSQFEQLAHNLIQACLVPCQNAIRDAKLQTSDIDEVILVGGSSRIPAVQTLVKNYFGKEPSKGVNPDEVVAVGAAIQGAILNKESGVGDIVLLDVTPLTLGIETMGGVMTKLIDANSTIPCKKSEVFSTAADNQTEVTIHVLQGERPMAAQNKSIGQFNLTGIAPARRGVPQIEVTFDIDANGILNVSAKDKATGKEQSIRIEASSGLSEEEINRMKAEAEQNAAADKAEREKIDKLNQADSMIFTTENFLKDNGDKIPADQKSGIESALQQLRDAHKSADVAAIDTAINNLNTVMQAASQQMYSQAGAQAGPQPGADAGQQEQPKQDDTIQDADFEEVK
>NZ_CP054011.1|WP_004360723.1|1189910_1190477_-|hypothetical-protein
MKKSIFTMLFLLLGMTTSFAQKVSVPEPEFADQTYLLTSDTEYQKLPRESGIIKSKAGASLYLVGIGKVKTRITLSGPTSSVTVPAGKDVRLIIKAANNSTDPESFINIFPFEVKGKERRAQLAEAGTLSATKTNSLGQISFKAKKYRQSSYYIVIENLKPGEYGISLGDPDKRNEKNDMKITTFSVK
>NZ_CP054011.1|WP_004360722.1|1190807_1191425_-|DUF4840-domain-containing-protein
MKRKNLFFLVIAFFATFSLASCLNDDYESKAKLPSVEELRAASHTIQGLYRGKLSRYGLNEREQLERKDSVNTTWEIKDDTTLIIKNIPTKMLTASIIDTDLKQAIEALPNQEIKCAISVFNVKPILFYIAPYRLDLGKITYGGKTHDVAIAFLFKNNYTYGGYDADRKVVGARLLEAGMVVDGVFDKSVSKGVDYFFLASEPRV
>NZ_CP054011.1|WP_004360721.1|1191844_1193302_-|TrkH-family-potassium-uptake-protein
MLNLKLISKILGSLLWIEGVLMLSSLFVALFYHSIDIMPLVWSILITIVAGTAFRLLGRNADNLLGRRDAYFVVTISWILFTVFGTLPFMIGGYIGSFTDAFFEAMSGFTTTGATIIDYPEHLPKGILFWRSLTQWIGGLGIVFFTIAILPSMVGGSVKVFAAEATGPIKSKLHPRLSTSAKWIWVVYLVLTISCILSYKVCGMGWFDAFNYSMTSTATGGFSTESGSIATFHSPAEEYVCALFCFLSGVNFTLLYASVVGLDIKKLLKNSEFRFYTIMVLSFTIFISFELVYRNHYEIEHAFRSALFQVVSFITTTGLFSDDAAKWPHVTWVVLAACMFFGGCSGSTSGGIKSIRGVMLLKVVRNEFRQILHPNAVLPMKVDGVNIPQSKRVTLLGFIGLYLILTLFCAFTMIAVGIDNTNAITITLSSLGNVGPTLGMEIGPTMSWAQLPDLAKWICSFLMLVGRLELFTVLVLFSPAFWKEN
>NZ_CP054011.1|WP_004360720.1|1193304_1194645_-|Trk-system-potassium-transporter-TrkA
MKIIIAGAYAIGTYLAKLLSRNMQDIVLMDEDPENLEKISSEYDLLTMECSPTNIKGLKEAGVEHTDLFIAVTPSESANIASCVMAHQLGAKKTVARVDNPEYVEEHNKELFRQMGISDIIYPEILAAKDIINGLKMSWVRQRWDVHDGALVMLGIKLRETCEILDRPLKDICGPDDPYHVVAIKRNDETIIPGGNDTLQLYDLAYFMTTKQYIPYIRKIVGKEQYVDVQNVIFMGGGKTAARAVKMLPEYMNAKIIELNPARCEVLNDAFSEDRLVINGDGRDIGLLQEEGIRHTQAFVALTSNAETNILACLTAKRLGVRKTVASVENFDYVNTADGLDIGTIINKKALAASHIYQMMLDANVANVKFLMSINSDVAEFVPSLDSKITRKVVRELNLPKGMTIGGLVRNGEGMLVSGNTLIEAGDSVVVFCYNVDMKKVEKLFI
>NZ_CP054011.1|WP_004360719.1|1194687_1196607_-|1-deoxy-D-xylulose-5-phosphate-synthase
MSKENRFGLLNKIQSPADLRKLSLDDLPKLCQQLRKDIIEEVAVNPGHLGSSLGATEITVACHYVFNTPEDRIVWDVGHQAYGHKILTGRRESFCNNRKLNGLMPFPSPFESEYDTFTCGHASNSISAALGMAVASNLTKQHRHVVAIIGDGAMSGGLAFEGLNNVSSQPNDLLIILNDNDMSIDRAVGGMEQYLLKLDTNETYNRLRFKASQWLHDKGLLNDERRKGLLRFNNALKSALAHQQNMFEGMNIRYFGPFDGNNVEELVRILRQLKDMKGPKLLHLHTKKGKGYEPAEKSATVWHAPGKFDPETGKRIVQDCSNEPPKFQDVFGKTLLELAKKNPRIVGVTPAMPTGCSMNIMMDAMPDRTFDVGIAEAHAVTFSAGMAKDGLQPFCNIYSAFSQRAYDSIIHDAAILNLPVVLCLDRAGLVGEDGATHHGAFDMAFLRPIPNLTIASPMDERELRRLMYTAQLPDKGTFVIRYPRGNGVLTDWECPLKEIEVGTGRRLHDGWDVAILSIGPIGNDVEKAIKLIESAESPKTEGHCPSIAHYDMRFLKPLDDKLLEEVASRFSRIITIEDGVRNGGLGSAVTEWMSDHGYTPQITRMGMPDHFVEQGTVQQLREICGIDIESIKKELIKAK
>NZ_CP054011.1|WP_004360718.1|1196878_1197961_-|OmpA-family-protein
MKKFLIALSMLAMGITSTQAQVAYEKAKAFDNVYLGVEGGVAAPLDFSRVTPLNAAAGLKLGKQFSPVYGANLEGLAFFGDNRWQTGSLGFSNSHTIVRAINLGLNGTINFTNLFCEYNPDRRFEVGAEAGIGYWITYGDKHIIQTNNTGDDTELTAKTGLTFAYNLGEKRAWQLYVEPAILWNLTHGPGDAIQFGKHAAQLGLFVGLNYKFKTSNGTHNFKVWNVGQLNDEINSLRDQLNAKPKEVVKEVVKEVVKEVPVQTTQTLCIDNLVFVTFAQGKYFLTNEAKKALDDVKAGRHVQIVGTASPEGPKALNDRLSQNRADVVAKYLQSRGVIVDEAKGQGVQGVTSNRLAVVYVK

Crispr_ID: NZ_CP054011_4

• CRISPR_ID: NZ_CP054011_4
• CRISPR_location: 1352761-1352849
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_4

Consensus_repeat	Method
AATATTCAACATCCATCACCCAA	CRISPRCasFinder

spacers of NZ_CP054011_4

>4.1|1352784|43|NZ_CP054011|CRISPRCasFinder
TATTCAGCACCCAGCAAGTAATAAACAGAAATCATCAACACCA

CRISPR arrays and Neighbor proteins around NZ_CP054011_4

CRISPR arrays

The CRISPR arrays of NZ_CP054011_4

>merge|NZ_CP054011|4|1352761-1352849|CRISPRCasFinder
AATATTCAACATCCATCACCCAATATTCAGCACCCAGCAAGTAATAAACAGAAATCATCAACACCAAATATTCAACACCCATCACCCAA

>NZ_CP054011|4|4|1352761-1352849|CRISPRCasFinder
AATATTCAACATCCATCACCCAA	TATTCAGCACCCAGCAAGTAATAAACAGAAATCATCAACACCA
AATATTCAACACCCATCACCCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_172891391.1|1362624_1363524_+|DUF559-domain-containing-protein	unknown	unknown	gnl|CDD|260015
NZ_CP054011.1|WP_036886878.1|1347463_1349509_-|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|227278
NZ_CP054011.1|WP_004361696.1|1363893_1364751_-|enoyl-ACP-reductase	unknown	unknown	gnl|CDD|187630
NZ_CP054011.1|WP_004361434.1|1360675_1362496_+|arginine--tRNA-ligase	unknown	unknown	gnl|CDD|223097
NZ_CP054011.1|WP_004361429.1|1352175_1352613_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NZ_CP054011.1|WP_172891390.1|1343346_1343484_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004361432.1|1355734_1359184_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|350195
NZ_CP054011.1|WP_004361430.1|1352860_1354198_+|dNTP-triphosphohydrolase	unknown	unknown	gnl|CDD|234897
NZ_CP054011.1|WP_004361424.1|1343669_1344785_-|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NZ_CP054011.1|WP_004361431.1|1354472_1355468_+|esterase	unknown	unknown	gnl|CDD|283403
NZ_CP054011.1|WP_172891392.1|1365250_1365613_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004361423.1|1342767_1343265_-|CYTH-domain-containing-protein	unknown	unknown	gnl|CDD|143629
NZ_CP054011.1|WP_036886880.1|1349509_1350421_-|DUF4292-domain-containing-protein	unknown	unknown	gnl|CDD|372917
NZ_CP054011.1|WP_004361425.1|1344956_1346765_-|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|223953
NZ_CP054011.1|WP_004361422.1|1342415_1342808_+|VanZ-family-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_172891330.1|1365721_1367602_+|IS1634-family-transposase	unknown	unknown	gnl|CDD|227708
NZ_CP054011.1|WP_004361433.1|1359565_1360054_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_172891393.1|1367757_1368816_+|transposase	unknown	unknown	gnl|CDD|379252
NZ_CP054011.1|WP_004361421.1|1340981_1342343_-|sodium-dependent-transporter	unknown	unknown	gnl|CDD|271367
NZ_CP054011.1|WP_004361428.1|1350417_1352154_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_036886878.1|1347463_1349509_-|M23-family-metallopeptidase	gnl|CDD|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	8.53309e-22
NZ_CP054011.1|WP_004361696.1|1363893_1364751_-|enoyl-ACP-reductase	gnl|CDD|187630	cd05372, ENR_SDR, Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR. This bacterial subgroup of ENRs includes Escherichia coli ENR. ENR catalyzes the NAD(P)H-dependent reduction of enoyl-ACP in the last step of fatty acid biosynthesis. De novo fatty acid biosynthesis is catalyzed by the fatty acid synthetase complex, through the serial addition of 2-carbon subunits. In bacteria and plants,ENR catalyzes one of six synthetic steps in this process. Oilseed rape ENR, and also apparently the NADH-specific form of Escherichia coli ENR, is tetrameric. Although similar to the classical SDRs, this group does not have the canonical catalytic tetrad, nor does it have the typical Gly-rich NAD-binding pattern. Such so-called divergent SDRs have a GXXXXXSXA NAD-binding motif and a YXXMXXXK (or YXXXMXXXK) active site motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.17823e-97
NZ_CP054011.1|WP_004361434.1|1360675_1362496_+|arginine--tRNA-ligase	gnl|CDD|223097	COG0018, ArgS, Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	1.57355e-141
NZ_CP054011.1|WP_004361429.1|1352175_1352613_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	4.09589e-92
NZ_CP054011.1|WP_172891391.1|1362624_1363524_+|DUF559-domain-containing-protein	gnl|CDD|260015	cd13935, RNase_H_bacteria_like, RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. This family includes bacterial ribonuclease H (RNase H) enzymes. RNases are divided into two major families, Type 1 and Type 2, based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication, repair and transcription. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription.	1.95957e-62
NZ_CP054011.1|WP_004361432.1|1355734_1359184_+|AAA-family-ATPase	gnl|CDD|350195	cd18808, SF1_C_Upf1, C-terminal helicase domain of Upf1-like family helicases. The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), and similar proteins. They are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	3.00188e-37
NZ_CP054011.1|WP_004361430.1|1352860_1354198_+|dNTP-triphosphohydrolase	gnl|CDD|234897	PRK01096, PRK01096, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	7.55139e-140
NZ_CP054011.1|WP_004361424.1|1343669_1344785_-|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	3.30728e-151
NZ_CP054011.1|WP_004361431.1|1354472_1355468_+|esterase	gnl|CDD|283403	pfam05728, UPF0227, Uncharacterized protein family (UPF0227). Despite being classed as uncharacterized proteins, the members of this family are almost certainly enzymes that are distantly related to the pfam00561.	5.87491e-13
NZ_CP054011.1|WP_004361423.1|1342767_1343265_-|CYTH-domain-containing-protein	gnl|CDD|143629	cd07891, CYTH-like_CthTTM-like_1, CYTH-like Clostridium thermocellum TTM-like subgroup 1. This subgroup contains the triphosphate tunnel metalloenzyme (TTM) from Clostridium thermocellum (CthTTM) and similar proteins. These are found primarily in bacteria. CthTTM is a metal dependent tripolyphosphatase, nucleoside triphosphatase, and nucleoside tetraphosphatase. It hydrolyzes the beta-gamma phosphoanhydride linkage of triphosphate-containing substrates including tripolyphosphate, nucleoside triphosphates and nucleoside tetraphosphates. These substrates are hydrolyzed, releasing Pi. Mg++ or Mn++ are required for the enzyme's activity. CthTTM appears to have no adenylate cyclase activity. This subgroup consists chiefly of bacterial sequences. These enzymes are members of the CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) superfamily, which have a unique active site located within an eight-stranded beta barrel.	6.74506e-79
NZ_CP054011.1|WP_036886880.1|1349509_1350421_-|DUF4292-domain-containing-protein	gnl|CDD|372917	pfam14125, DUF4292, Domain of unknown function (DUF4292). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 243 and 287 amino acids in length.	3.55771e-32
NZ_CP054011.1|WP_004361425.1|1344956_1346765_-|long-chain-fatty-acid--CoA-ligase	gnl|CDD|223953	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism].	7.59985e-171
NZ_CP054011.1|WP_172891330.1|1365721_1367602_+|IS1634-family-transposase	gnl|CDD|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.29432e-12
NZ_CP054011.1|WP_172891393.1|1367757_1368816_+|transposase	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	0.00286554
NZ_CP054011.1|WP_004361421.1|1340981_1342343_-|sodium-dependent-transporter	gnl|CDD|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	0
NZ_CP054011.1|WP_004361428.1|1350417_1352154_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.29692e-26

Protein sequences

>NZ_CP054011.1|WP_004361429.1|1352175_1352613_-|dUTP-diphosphatase
MIQIKVINKGHQQLPAYATSQSAGMDLRANIDAPIVLRPMERRLIPTGLHIALPVGFEAQVRPRSGLALKHGLTVLNSPGTIDADYRGEIMVLLINFSDEPFTINDGERIAQMVIARHEQAEFVEVEELDETERGEGGYGHTGVK
>NZ_CP054011.1|WP_004361428.1|1350417_1352154_-|tetratricopeptide-repeat-protein
MFNNVILKVTMMRRTLLALALLGGSLAMYADRKDSLQSYNYFFLEAIRQQDMGNLTAAFDLLRHARELNPQAPEVYYHLAAFYVDMKKDAVAREYFEKAASLDPENSAYQEKLGKLYVSQKDYPNAIKAFERLYESNKTRSDVLQLLYQLYASQDDDKMMIKCLERLEVLEGTNEQISLSKMQLYEQMGEKRKEYDELKSLVDSHPLDLNYRVMFGNWLLQNGKKKEALQKYRDVLKEDPDNSLAKLSMMDYYNNIGDKATVKTILQELLQSPKTEKEAKLELLRQVITSSQKDNTPDSTEVMRLFSVALAVPQEDADIYMLKAAYMTLRKQPKGAVNRVYEQALEVEPDNSRARIALIQNIWDTQDYDKVIAICRPAIEYNPDEMAFYYFQGMAQFQKHDGDAALETFRKGVGQIKPDSDPSIVSDFYAIMGDILHEKGRNKEAFQAYDSCLQWKADNVAALNNYAYYLSEANENLTKAEQMSYKTIKAEPNNSTYLDTYAWILFQQKRYEEAKIYIEQAIRNDSTLSNVVKEHAGDIYAQTGDIEKALEFWRKALEGNKENATLRKKIELKKYIAE
>NZ_CP054011.1|WP_036886880.1|1349509_1350421_-|DUF4292-domain-containing-protein
MKKTKILLVSMTVLLLASCGTKKAVIQQKPVQDNKVAQQTAPATKDSKMQSVVVMQRVADNALYQKNLVSNLTFTLNDGHKDITVPGILRMRKDEVIRLQLLIPILRSEVGRIEFAKDYVLFIDRIHKQYVKASYDEVGFLRDNGINFYSLQSLFWNQVFIPRQQKVSEADLSQFAVDESKAQTEGSTLISLKDGKMDYKWSVNPKSNQIVLTTVTYNSNTHGASKLSWSYDDFKAFGSKLFPASQMLTINTPKFGQKPAKTLKASFDLESFSDASDWEVFTTPSDKYTKVSVEDILGKLMNF
>NZ_CP054011.1|WP_036886878.1|1347463_1349509_-|M23-family-metallopeptidase
MKRLSLLFILSIMCMLSVSAQHSRKHRKQQKAAVAQSVEPQTTVKGKGKKAINAINNNHAVAPATPVKGQKPIVEKLQTQPQPKGKQQQDKLQHQQQLKGQQPQVKGQQPQLKGQPAQVKGQQVVRGKAAVRNAHVGKKGAKGPAYVTTEEIKGLQQQNLKLQKEISEHEEEMKVKQKDVDDRLQKIVRLDTEIGQHQRTIDTIATDIKGLDSNIGILKGQLASLESQLGERRARFIRSMRYMARHRSIQDKLMFVFSAKNLTQMYRRLRFVREYAAYQRAQGEQLKAKQMQVDEKHTQLKQVRVNKSNLLYKDRLVHAQMERKRVEQQTVVNSLQNDQKVLQGVIAQRRQQQQALNAQIDRLIQIEIQKARERAIAEAKAQAAARAAAAKKRAEELARKKAAAEVAARENARRIAEAKEREAKAKAAARAAAEAAEKARQEAAARAAAARAAAEKARQEALQKERAAARDRAIRKAEEQEAAAKAAQEKAEARAAAEKARADQMAREAEANRVAAERKADADRERAAREAEAARASAAESNDMLSSADRAITGNFANNRGRLPMPLSGQIVSHFGQYNVAGMSNIRLNNDGINIKGAPGSAVRSVFMGEVSGVFMAGGMSVVMIRHGIYITVYANLGSVGVSKGQKVGTGQTIGTVGRTGILQFQLRKETAKLNPEQWLR
>NZ_CP054011.1|WP_004361425.1|1344956_1346765_-|long-chain-fatty-acid--CoA-ligase
MQTIGHLSVLIHEQAKKYGAKPAITFRNFGSLDWKTVSWNQFSMRVKEVSNALLNLGMKPQETIAVFSQNCIHHLYTDYGAYGVRVISIPFYATSSEQQIQYMIQDANVRFLFVGEQEQYDKARRIQSLCPTLERIIVFDSSVRLSQHDPNSIYFADFLKLGEGFPREAEVKERWAHANYDDICNILYTSGTTGESKGVILTYKMYQAAMDANRKSVPVNEKDRVINFLPFSHVFERGWACLSLAAGAELIVNTYPKEIQQSMRETHPTSMASVPRFWEKVYVAVKERMDKSSVVQRKLFYHALNVGRKRNIQYLARGKRVPLALEMEYKFVNKTVLSLVRKQLGLENPHLFPTAGAYVSPEVEEFVHSIGITMIVGYGLTESLATVTCDHVGQPYTVGSVGRPLEGIDIKISDEGEVMLKGPTIMPGYFRRDTANAEAFDKDGYFHTGDAGYMKDGELFLKERIKDLFKTSNGKYIAPQMVEAMLLVDKFIEQVSVIADQRKFVSALIVPEYSVLEEWARENHIEFKDREELCQDKRVNDMMRERIETLQQRLASYEKIKRFTLLAHHFSMENGELTNTLKLKRSVVNRRYHDVIEKMYEE
>NZ_CP054011.1|WP_004361424.1|1343669_1344785_-|peptide-chain-release-factor-2
MITADQLKDIQERTEALHRYLDIDKKRIEFEEEQLRTQAPDFWDDPARAQEQMKKVKDIEKWVKDYDKARALADEVQLAFDFYKDELVTEEEVDTAYAKVLKVIEGLELKNMLRQEEDPMECVMKINSGAGGTESQDWASMLMRMYMRWGEAQGYRVTISDIQEGDEAGIKSVTMKFEGGEYAYGYLKSENGVHRLVRVSPFNAQGKRMTSFASVFVTPLVDDTIEVYVDPARVSWDTFRSSGAGGQNVNKVESGVRLRYQYEDPDTGEQEEILIENTETRDQPKNRAKAMQLLKSQLYDRAMKKRMEEQAKIEAGKKKIEWGSQIRSYVFDDRRVKDHRTNYQTSDVDGVMDGKIDDFIKAYLMEFPTEE
>NZ_CP054011.1|WP_172891390.1|1343346_1343484_-|hypothetical-protein
MSERSKVNRKERELKQEKQANRVVAWLAVILVALGVLTIIIASNS
>NZ_CP054011.1|WP_004361423.1|1342767_1343265_-|CYTH-domain-containing-protein
MSGLEIERKFLVHKNMDWKSLASSCSHIQQGYFAAVNTVRVRIRDDKGYLTIKGPSRTGGLSRYEFEKEITLEEAQQLMLLCEPGVIDKHRYLVPFEGHTFEIDEFHGDNDGLVLAEVELGSEDESFDKPDFIGLEITGNRHFYNSQMRRNPFKLWRDIVPEEYR
>NZ_CP054011.1|WP_004361422.1|1342415_1342808_+|VanZ-family-protein
MSITKHILTKYPFSCIIVIGTWILCFMTIPETPLSSVRFIDKWTHSLIYLVLGLSISLEYLRNTKQPSPKFIIVWVWLMPIIMGGLIEVLQSYCTNGNRSGEWLDFFADAIGSTIAVLIGILLVRYRAKA
>NZ_CP054011.1|WP_004361421.1|1340981_1342343_-|sodium-dependent-transporter
MSEQKRAKFGSKLGMILATAGGAVGLGNVWRFPYMTGQNGGAAFILIYIGCILLLGLPCMISEFIIGRHAASNTARAYTKLSNGSAWKWVGYLGVLTGFLITGYYAVVSGWCLQYGVASVMNHLHGTPDYFKSYFTDFSTNPWKPVLWTVAILFLAHYIIIHGVRNGIERASKIMMPALFVLLVAIVVASCLLPGASKGVEFLLKPDFSKVTGDVFLGALGQSFYSMSIAMGCICTYASYYSRHTKLLNSAVQIGVIDTCVAILAGLMIFPAAFSVGVSPDSGPSLIFITLPNVFEQAFASMPIVGYIISMAFYLLLSMAALTSLISLHEVSTAFFQEELHISRPRAAMIVTAACSLIGAVCSLSLGEWSFLKVAGVDLFDLFDFVTGQIFLPIGGLLTCLFIGWYVPKKLVKDEFTNWGTTRGIFFGAYYFLIRFVCPLAILAIFLHQLGVF
>NZ_CP054011.1|WP_004361430.1|1352860_1354198_+|dNTP-triphosphohydrolase
MNWQQLISNKRLGQEERHALRHDDRSEFKRDSDRLIYSAPFRRLQNKTQVFPLPGSVFVHNRLTHSLEVASLGKSLGDDVARRLIEIHPELRGTLFEEIGTIVQTACYAHDMGNPPFGHSGEKAMQAFFTEGSGISLKDKVSPHFWEDITHFEGNANAFRLLTHRFLGRREGGFVMTYSTLASIVKYPFSSTYASKHGKFGFFATEEETYKKIADELGIIQKDSSEAGICYVRHPLTYLMEAADDICYEIMDIEDSHKLKLLSFEETADLLLGFFDEETRKSIRKRIEEEGVTDQNEQVVYFRACAVGLLEAECVNVFVEHEEEILNGTFEGSLIKHISELPRQAYKRCTEVSVDRIYRSKAVLDVELSGYKIMETLMEALIGAAVEPEHFHSKQLIRRFSSQYDIQSPCLETRIMAVLDFISGMTDIYALDIYQKINGISLPLI
>NZ_CP054011.1|WP_004361431.1|1354472_1355468_+|esterase
MENQYKKTFPDLMVGKKIIYVHGFMSAGSSHTVQILRDYMPEATVIAPDLPIHPEEAMELLRNLVDSEKPDLIIGTSMGGMYTEMLYGVDRICVNPAFQMGTTISETNMMGKQVFQNPRQDGVQEVIVTKALVKEYKEITEKCFSQVTEEEQQRVFGLFGDADPVVHTFDLFHEHYPQAIRFHGEHRLIEKAVFHYLMPVIRWIDDRQEGRERRTALIDQNTLADGYGKPKSSLNKAYEFLLDNYNVFFVCPAPTNYPSTITEQQAWIEDAFSAPAWNHTIFTNQPHLLYGDYFISSTEHDDFLGTSLLFGSEEFKTWEEIITFFERLGGQ
>NZ_CP054011.1|WP_004361432.1|1355734_1359184_+|AAA-family-ATPase
MAHELFSRIADILSAPSEAQALIMHETLVIACHEGLKNTRHGFGNLSSQVESLCRQHNIAPQDIVAIQKMRRHSNSYAPILPEDVAYDCRALAIFVSAVVQEAIPSFLVGKIPAHGRITENIQITNYRYIRCIVREWDESTIQVAVTNQDSSEELLLVDYMNTPDYIDFSYLRPMLREGMQLNLLDCTVTRKKVVPRLIVVEPDYLIDISTIANCFETYGHHPLLFTVNRLTPRLSNKHIVLGNFAGSALDDIINHPAEYDIKDTFRSNFKEKALDYATCPDFDAASFKQDAERQVENIKGIVDEIFQTFDREKAILEPSFVCERLGIQGRVDLMTTDLKLLVEQKSGKNTFIERKYKNSHGSLHVEKHYVQVLLYYGILQYNFQLSPKNAHIQLLYSKYPLPDGLLEVEPLQKLIREAIRFRNQAVATEFWMADNGFDRMLPLLTPQTLNTEKQNDNFYNRYLLPQLTETLAPLHQLNDLERAYFTRMMTFVIKEQLVSKVGVQEGVGNSNADLWNMPLAEKKETGNIYTELTITEKERSNSFNGYDTITLSVPQQGEDFLPNFRRGDMIYLYAYKKNEAPDVRMSILFKGSLQEIHGDRLVVHLNDGQQNPDLISGDYFAIEHAGSDIGGTSAIRSLYTFITSPEERRQLLLGQRAPRSDKSLTLSRSYHPDYDEIILKAKQAQDYFLLIGPPGTGKTSQALQFLVREQLAGNIYSQPSSAYSAEDSKHNKLSETINTQHPTPNTQTSILLLAYTNRAVDEICNMLTENELDYIRIGNEFSCDPKYSDHLLKEVLDDNATLNSIKSTLADARIVVATTSTMNSNAALFNIKHFDLAIIDEASQILEPNIIGLLSTRHAERRAIKRFILIGDHKQLPAVVQQQDTLETEETNTFLKNIHLLSCANSLFERLILTERTAGRTDFIGTLHKQGRMHPDIADFANRKFYAREQLECVPLAHQMEQTLAYNETSEDETDDLLKAHRMIFIPSKPCRQLNISEKVNTEEARIITDLLRRLHRQLGNNFDSQKSVGVIVPYRNQIAMIRKEIEKLGIPELEEISIDTVERYQGSQRDIILYSFTIQSRYQLDFLTANTFYEDGQPIDRKLNVAITRARKQLILTGNEPTLRQNQIFAELIDYIKEKGGYYAEKA
>NZ_CP054011.1|WP_004361433.1|1359565_1360054_-|hypothetical-protein
MRKSIQKWTYVLVSSVFALVMCFSLSACGSDDDNDVNNGISPVLYSDFGGRIGVNYSLDISGKMVSFFIPKSQAGQIVDLTKGGDWVAGGSAVGGLYSYGDHLFQKGSYVYLLKTGANEIELRYKYIWKEGTATRTIEGNYKNVKMTTHQGAIDWAHRQGLY
>NZ_CP054011.1|WP_004361434.1|1360675_1362496_+|arginine--tRNA-ligase
MKIEEQITVAALAAVKELYGTEVPEKMIQLQKTRSDFEGNLTLVTFPLLKTSHKKPEDTAQDLGEYLKKNCKAVADFNVVKGFLNLVIAQAAWTGLLNDINADEKFGEKRVTDESPLVMIEYSSPNTNKPLHLGHVRNNLLGWSLAQIMEANGNKVVKTNIVNDRGIHICKSMLAWQKWGNGITPEQAGKKGDHLIGDFYVLFDKHYKEECKQLQEQYEKEGMTADEAKKKAEHEAPLIKEAHDMLVKWEANDPEIRALWEKMNNWVYAGFDETYKAMGVGFDKIYYESNTYLVGKKKVEEGLEKGLFIRKEDNSVWADLTNEGLDQKLLLRKDGTSVYMTQDIGTAEMRFNDYPIDKMIYVVGNEQNYHFQVLSILLDRLGFKWGKDLVHFSYGMVELPNGKMKSREGTVVDADDLVASMIENAKSLSEDKVNKLEGITEEEKNEIARIVGMGALKYFILKVDARKNMLFNPEESIDFNGNTGPFIQYTYARIRSILRKAEAQNITLPATLNDDAPLNEKEIALIQKLNDFGAAVAQAGIDYSPSGIANYCYELTKEFNQFYHDYSILNADTEAEKIARLMIAKNVAKVIKNGMALLGIEVPERM
>NZ_CP054011.1|WP_172891391.1|1362624_1363524_+|DUF559-domain-containing-protein
MYIYETADEIEYELLKANAIKNRQHSTQAENLLWLYLKGKQSGHKFRRQHIIGQYIADFINLKYKLIVEIDGKYHFNDEQIIKDEERTRDLEQWGYTVIRFTNEEVFNHREEVIQKIKETIMAIDSHNTTQTGDSLINTPSNSQTNTQSAIRPQQTGASPLSGGLRGAGAWAVDAACSGNPGPMEYQCVDLQTGARVFHFGPVIGTNNIGEFLAIVHALALMEKQGIKDKVIYSDSYNAILWVNKKRCKTTLVRNANTEQLHQVISRAEHWLQTHKVTTPIIKWETKQWGEIPADFGRK
>NZ_CP054011.1|WP_004361696.1|1363893_1364751_-|enoyl-ACP-reductase
MSYNLLKGKRGVIFGALNEMSIAWKVAERAVEEGAMITLSNTPIAVRMGTVNALSEKLNCEVIPADATNVEDLENVFKRSMEVLGGKIDFVLHSIGMSPNVRKHRTYDDLDYKMLDSTLDISAVSFHKMIQSAKKLDAINDYGSILALSYVAAQRTFYGYNDMADAKALLESIGRSFGYIYGREKHVRINTISQSPTMTTAGSGVKGMDKLFDFADRMSPLGNASADECADYCIVMFSDLTRKVTMQNLYHDGGFSNVGMSLRAMATYEKGLDEYKDENGNIIYG
>NZ_CP054011.1|WP_172891392.1|1365250_1365613_+|hypothetical-protein
MDAKLDNLSEISKLLSVKSKMSSDILSLFSKFGFGRLLCRLSLEKHDGISAVQQILSLCLFRINGETIHSIYKKNFYHLLTTGKNCYYRMMVRQAMNWRRLLSPSLTGKIIFHKFSGCFV
>NZ_CP054011.1|WP_172891330.1|1365721_1367602_+|IS1634-family-transposase
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKTRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYSGVPGWTPGINSLYKITDKLYELKEQLERHLCSVTDDIFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINQEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVVMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDEDYYLEITSPSKAMTESSMNRVWKERFEMELQRINEGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKKPKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNDLNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGETIEMRQCGSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054011.1|WP_172891393.1|1367757_1368816_+|transposase
MEKTGRKFEHITKVFDHVRMNYVLGYKLLLCLFFDGKSSLPFDFSIHEELGKKGDGGLGKKALRSRFSKRRMKESPAYERNQECGMSKMDSAIRMLQRMWKRGIHPHYALADSWFACEKFIEEIRRVGNGAIHYIGLAKMGKTKYFVENKRHNAAELVAMYARRTKCCRKYKCQYIELRGCLGNIPVRIYLIKYGRRQTWNIMLSTDLSMSFVRAFELYQIRWNIEVVNKETKGHLGLGSYMGRDFDGQIADATLCYITYIVMSLEKRMSEYETMGELFADMEDDVMALTLWHRVLNCIERLLAALCDVLGFSVSEIGQLIVTDSAMRNNFEIMVQALEDRQQEKLTTVNIF

Crispr_ID: NZ_CP054011_5

• CRISPR_ID: NZ_CP054011_5
• CRISPR_location: 1390386-1390481
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_5

Consensus_repeat	Method
CCCCTACTTTATCCCATTAGGCTCTCCCCT	CRISPRCasFinder

spacers of NZ_CP054011_5

>5.1|1390416|36|NZ_CP054011|CRISPRCasFinder
ACCTGATGTTGCAACCATGGGGAATTATAGAGTTGT

CRISPR arrays and Neighbor proteins around NZ_CP054011_5

CRISPR arrays

The CRISPR arrays of NZ_CP054011_5

>merge|NZ_CP054011|5|1390386-1390481|CRISPRCasFinder
CCCCTACTTTATCCCATTAGGCTCTCCCCTACCTGATGTTGCAACCATGGGGAATTATAGAGTTGTCCCCTACTTTATCCCGTTAGGCTCTCCCCT

>NZ_CP054011|5|5|1390386-1390481|CRISPRCasFinder
CCCCTACTTTATCCCATTAGGCTCTCCCCT	ACCTGATGTTGCAACCATGGGGAATTATAGAGTTGT
CCCCTACTTTATCCCGTTAGGCTCTCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004360959.1|1380307_1380961_+|DUF4145-domain-containing-protein	unknown	unknown	gnl|CDD|372658
NZ_CP054011.1|WP_081445996.1|1396470_1396806_+|transporter	unknown	unknown	unknown
NZ_CP054011.1|WP_004360971.1|1395475_1396474_+|SPFH-domain-containing-protein	unknown	unknown	gnl|CDD|259806
NZ_CP054011.1|WP_004360968.1|1389374_1390247_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl|CDD|179769
NZ_CP054011.1|WP_004360966.1|1387385_1387856_-|transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
NZ_CP054011.1|WP_004360962.1|1383947_1384412_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360967.1|1388790_1389378_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl|CDD|237411
NZ_CP054011.1|WP_004360969.1|1390508_1391486_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl|CDD|223428
NZ_CP054011.1|WP_004360964.1|1386203_1386881_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360978.1|1406883_1407597_-|DUF4919-domain-containing-protein	unknown	unknown	gnl|CDD|379813
NZ_CP054011.1|WP_036886687.1|1392306_1394772_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP054011.1|WP_004360958.1|1377007_1380292_+|Eco57I-restriction-modification-methylase-domain-containing-protein	unknown	unknown	gnl|CDD|380297
NZ_CP054011.1|WP_004360976.1|1401450_1402989_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360960.1|1380964_1382719_+|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225420
NZ_CP054011.1|WP_004360963.1|1385042_1386134_+|mannose-1-phosphate-guanylyltransferase	unknown	unknown	gnl|CDD|223906
NZ_CP054011.1|WP_004360965.1|1386965_1387364_-|HIT-family-protein	unknown	unknown	gnl|CDD|223611
NZ_CP054011.1|WP_004360975.1|1401195_1401411_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360979.1|1407743_1409285_-|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl|CDD|223679
NZ_CP054011.1|WP_004360972.1|1396826_1398188_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004360973.1|1398344_1399106_+|hypothetical-protein	unknown	unknown	gnl|CDD|225405

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004360959.1|1380307_1380961_+|DUF4145-domain-containing-protein	gnl|CDD|372658	pfam13643, DUF4145, Domain of unknown function (DUF4145). This domain is found in a variety of restriction endonuclease enzymes. The exact function of this domain is uncertain.	1.12283e-13
NZ_CP054011.1|WP_004360968.1|1389374_1390247_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl|CDD|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NZ_CP054011.1|WP_004360966.1|1387385_1387856_-|transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	1.25032e-60
NZ_CP054011.1|WP_004360967.1|1388790_1389378_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl|CDD|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	2.00479e-103
NZ_CP054011.1|WP_004360969.1|1390508_1391486_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl|CDD|223428	COG0351, ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme metabolism].	1.32381e-54
NZ_CP054011.1|WP_004360971.1|1395475_1396474_+|SPFH-domain-containing-protein	gnl|CDD|259806	cd03408, SPFH_like_u1, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and, in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	1.017e-69
NZ_CP054011.1|WP_004360978.1|1406883_1407597_-|DUF4919-domain-containing-protein	gnl|CDD|379813	pfam16266, DUF4919, Domain of unknown function (DUF4919). This family consists of uncharacterized proteins around 230 residues in length and is mainly found in various Bacteroides and Prevotella species. The function of this family is unknown.	7.00892e-11
NZ_CP054011.1|WP_036886687.1|1392306_1394772_+|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.92972e-57
NZ_CP054011.1|WP_004360958.1|1377007_1380292_+|Eco57I-restriction-modification-methylase-domain-containing-protein	gnl|CDD|380297	NF033455, BREX_6_MTaseX, BREX-6 system adenine-specific DNA-methyltransferase PglX.	2.81246e-11
NZ_CP054011.1|WP_004360960.1|1380964_1382719_+|putative-DNA-binding-domain-containing-protein	gnl|CDD|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	1.96433e-42
NZ_CP054011.1|WP_004360963.1|1385042_1386134_+|mannose-1-phosphate-guanylyltransferase	gnl|CDD|223906	COG0836, {ManC}, Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane].	8.64298e-107
NZ_CP054011.1|WP_004360965.1|1386965_1387364_-|HIT-family-protein	gnl|CDD|223611	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only].	3.96423e-34
NZ_CP054011.1|WP_004360979.1|1407743_1409285_-|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP054011.1|WP_004360973.1|1398344_1399106_+|hypothetical-protein	gnl|CDD|225405	COG2849, COG2849, Uncharacterized protein conserved in bacteria [Function unknown].	4.32896e-09

Protein sequences

>NZ_CP054011.1|WP_004360968.1|1389374_1390247_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MANRQELNRNLAQMLKGGVIMDVTTPEQARIAEAAGACAVMALERIPADIRAAGGVSRMSDPKMIKGIQEAVTIPVMAKCRIGHIAEAQILQAIEIDYIDESEVLSPADNIYHIDKTQFEVPFVCGARNLSEALRRIAEGATMIRTKGEPGTGDVVQAVSHMRLMQSQIRELVSKREDELFEAAKQLQAPYDLVKYVHENGKLPVVNFAAGGVATPADAALMMQLGAEGVFVGSGIFKSGDPAKRAAAIVKAVTNYNNPKELAALSEDLGEAMVGINEHEIEVLMAERGQ
>NZ_CP054011.1|WP_004360967.1|1388790_1389378_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MRIAVLALQGAFLEHEMMLRKLGIDCFEVRRLEDWQQEKDGLIIPGGESTTQGKLLRDLSLLDPIREAIEAGLPVFGTCAGLILLAREVEGNSPSAPVPPRLGTMRMTAARNAYGRQLGSFHTEAPFKGVDGDIPMTFIRAPYIKESADEVETLSEVEGHIVAARQGNQLVTAFHPELDSDMRVHEYFLEMVKGR
>NZ_CP054011.1|WP_004360966.1|1387385_1387856_-|transcription-elongation-factor-GreA
MAYMSQEGYDKLVADLQYLESVERPKASAAIAEAADKGDLSENSEYDAAKEAQRHLEARIAELKMTVAQAKIVDVSRLSTDAVQIMSTVEMTNVKTNAKMKYTIVSETEANLKQNKISIKTPIAQGLLNKKVGDEVEITIPRGTITLRIDKISIDA
>NZ_CP054011.1|WP_004360965.1|1386965_1387364_-|HIT-family-protein
MTIFSKIAAGEIPSYKCAENEQFYAFLDIDPVTKGHTLVIPRKEVDYIFDMEDEELAAFEVFAKKVARAIKAVFPCKKVAQVVLGLEVNHAHIHLLPMNSEADVDFKHHVPVDAEEQKEIAEKIFKAFQELD
>NZ_CP054011.1|WP_004360964.1|1386203_1386881_-|hypothetical-protein
MKETKDDNWSDWLINDKLRWERFTFFGRKERVSMWTGIVLGCLLFTAILVVAFLLIKKGNKLYDNTMLPFDSGEINYITIWFVLNVILSVIVFISKKSLRNDSNRIFNFFLLMVFNLLPSYFILGILFFTILYPNSSYGEKETINQRAIFTGKVRRVSRSNSVFCYSFYLPNMNRNVVISSGFDYDWKDKTACDIYLHKGYFGMYVVDSAVYKENQYYSTTLVAE
>NZ_CP054011.1|WP_004360963.1|1385042_1386134_+|mannose-1-phosphate-guanylyltransferase
MTTKQNNYCVILAGGKGRRLWPCSRDKYPKQFIDFFGVGRTQLQQTFDRFANILPKENIYINTSCDYLDLVREQLPEVAADHIMAEPIHRNTAPSVAWAVHRIMMFDPKANIIISPSDHNIVNDEAFFRNIKEGLSFVEKNDAILTMGVSPTRPEPGYGYIQKGVYTGNGDIYKVQAFTEKPDREFAQMFMDSKEWCWNTGLFLSNVNYLRQSLYGFLPSVLREGEMGSKITTIEDEEAFIHDNFPRYPNISLDYGILEKSENVYVMRCDFGWADLGTWHGVYESLSKRDGDNVVIDSDVILEDAANNIIKLSKGKLGVINGLDGYIIAEKDNVLLICKKEDSSALVRKYVNEVQIKKGEEFV
>NZ_CP054011.1|WP_004360962.1|1383947_1384412_+|hypothetical-protein
MIVTTEYIGNQELLKLQKTAFLASSNIATETVLQVYDWATEMRSRGDCIISGFNSKLEQDVLHFLLKGSQPIILVIARRMYKTIPTHLQTALKQNRLLIISISNSTRQSKATALERNKYICHLAEKILFAGVTEQSSLYALQNTENNKAKLITL
>NZ_CP054011.1|WP_004360960.1|1380964_1382719_+|putative-DNA-binding-domain-containing-protein
MSKLTIEHLKTLRESEDKVEFKRAAQGNFAYDGGSKPNPKDRRKCILGYVTALCNEGGGYLVLGMEDAYPHQVVGTKQNKGAIGELESYIYRDTSIRPSIYELYEDETTKEGRVLVIDVPGRPIGKLFRFEDVPLMRVGEELKPMSDEEIFKILQEQEPDFSSEICSTVSINDLDTEAIRILKQKYATKQKNPNFLTLPDEQVLSDLQLMKEGKVTYAALILVGKREKLIELLPQASVILEYRKSENLVPYDNRYTYSEPFYKMIDMLWHDINLRNDKIDVNDNSYIFNIPFFNEDVIREAINNAIAHRDYRRTSETVIKQYPQKLIVMNAGGFPLGVSIDNLLRVQSTPRNRLLADVLEKTGIVERSGQGIDKIFKNTLSEGKDSPDYSHSDSFRVELHLSAVIKDKAFAMFLESEQRDLAEEDRLSVFDVISLNEVRQGKSQSVEKDSIEKLLSCGLIEKRGRTRGTYYILSKSYYEFSGQEGEYSQKDDWGINQVMSVIMPHLTKFGKAKMKDFAKLLDGHLTRRQVRTVIDKLVAYQLLIKEGEGASTTYKIAEKYIKNSALVARAFDLGIKEMKKRGEI
>NZ_CP054011.1|WP_004360959.1|1380307_1380961_+|DUF4145-domain-containing-protein
MNQKYVTPARDKDAFTCPHCHTLSLMKFRWHRHDEDVHFVTQRVGYGEYLNQLFIARCVNCGKKIIWINDDYIYPDIVAEDPNVDMPESVKQLYNEAGTIYNKSPRAACALLRLAIDRLCNELGETDRDINKNIGILVKKGLPQAVQQALDVVRVVGNKAVHPGVISFDVDDKGTATMLMHLLNIITERMITEPKEIESLYEGLPETVKESITKRDK
>NZ_CP054011.1|WP_004360958.1|1377007_1380292_+|Eco57I-restriction-modification-methylase-domain-containing-protein
MKRNIFNQYITVSDFKGLFVSEMLWNNPTGATQLPEINIDNTTFHIEQIAERKGFQILHCHVEQIPSSAICKKIDHKIRKNAENYICIFILPETLHHLWVAPVKKVEKRDVVLVEYDSLDKAAFLFEKIESLSFSLDDNLTILDIIEKVQSAFLINSEKITKDFYAGFKKEHSNFAKFITGIDDHIDEKENKNKQWYASVMLNRLMFCYFIQKKEFLDGDVNYLRHKLEWTRNQEGEDRFFNKFYKGFLVNLFHDGLNTPKHNHEFEKIYGRIPYLNGGMFDVHQIEREYANLDIADEAFISLFDFFDKWHWHLDDRMTASGRDINPDVLGYIFEQYINDRAQMGAYYTKEDITEYIGRNTIVPYLMDAVKRKDEKHFRANSELWLYLKESGDKYIFDAMKKGVDQTIPEEIATGLDTTKPNLLERRCHWNERTPEAFALPTEIWRETIERLQRYNNIKEKIVKGEITNVNDFITYNLNIRQFVTDYLANTQDHLFVKHFYHALQHVTILDPTCGSGAFLFAALNILEPLYEVCINRMQEFNAKNPLLFKRELQEIEHKYRSNIQYFIYKSIILRNLYGVDIMVEATEIAKLRLFLKMVAVVEVDKHDPNLGLDPLPDIDFNIRCGNTLVGYATQEELERDLIEGDMFARKEFKAKVNDEMDKVSRTYEIFKNVQLHQAEDMAAFKKAKSELYQRLNTLNDLLNHKMYGAVESTKGYDAWYQTHQPFHWLAEFYEIINEHGGFDVIIGNPPYVEYNKKVKGVAVSDLYKLVGYKTLSCGNLYAYVLERSKNIMRQEGYISMIVPLSGHSTERMAPLVTNFYEKFRLHLHLNLSADANPQKLFEGVKFRLVIFTATNNGVGKYSTKYTRWLADERKNLFNALVRYNSIEDYTYQNIIPKIASPLFISIARKIKEEKAQYFVGIGNEQCLYHNAPVNWIRSHTFVPYFCSDRDGEGITTQLKSVSFDNTKQVKVGSCILNSSLFFIWWITNSDCYHLNKPEIVNFRYQYDKGIEKEICSVADRLAIDMKKKCIRRIYNYKTTGRVEYDEFYMKLSKPIIDEIDKFLARHYDFTEEELDFIINYDIKYRMGDELNEE
>NZ_CP054011.1|WP_004360969.1|1390508_1391486_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MQNNKPKLLKTILTITGSDSTGGSGVQADIRTIATLGGYAVSAVTSVTVQNTLGIQAFYDLPAEIVRGQIEAIINDMQPDTVKVGMIRTIETLAVVVDALLKYRPHHIIYDPIVTASNGDRLMTDDVITQIRCRLLPLCSLVILREGEAERIFDCSSLIGEGRRTVRSFVLDDPLQHGLANSFSSALAVYLSQEEPMNEALQHAREYVRTLVARKSDISGRSSQLYNEFLEAVQLHYHTNRDVAFYADCLNVSPRYLSQVAHRISGKSPKCIIDHTLAEALACQLRTTQKTIQEIGYEHGFASQAQFSKFFKKQMGQTPSEWRRS
>NZ_CP054011.1|WP_036886687.1|1392306_1394772_+|TonB-dependent-receptor
MKKYLLILTAMLCSLVSMAQNTDAMLFGDVKAKEGGKHLSHAVIQVKGTNLKTQCDASGHFKLSNLPVGKQVIIATLAGYQQQEKEVDMVNNKGSEVYFELEKDPLELSQVVVTGTRTSHFVKDVPIRTEVLTSQAITKKNAQNLYEALEGVPGIRVEQQCQFCNFSEVRMQGLGAEHTQVLIDGEPIYSGLAGVYGLQQIGTNDIDRLEVVKGAGSALYGSSAVAGAINIISKEPTFEPSVNGDIQFGNFGFKSYKGSGSMRYNNIGLSVFAQRTQMDAIDRTQNGLTRKEVKNKDGISDRVDETVNNLGFSLYFYQPFAKNDKLVLRGKAIDEHRFGGVMTNDQYLNPYTDGTEDIRTNRLSADLAYTLPIGKHSELNLTTAYVYHKRQATNDTFLHDYMDSHKDPAHPDQDGAEPDVSMMRPYIAKENTVTPSLTFTSILGNHTLLGGVQGYFTRLRETGLYVISAEDEKTSPYYGVPYTSIGKKHANELGFFVQDEWNVTPKLTVVPGIRIDSHSSGEEYATSVKVSDSAFPTTKFSKTTVNPRIAIKYELTPSLVLRANVGTGFRAPYGFSEDLHLCSGSPRVWKSSNLKGERAISYNLSADYYAKKYQFSINIFRTNLKDKIQFSPADDEVKKFGYSYQWENVDDAYVQGVELGAKANLFRNFNAGINWTFNQGKFKHERADWSDPNDETVKEFPQRLQYAKDSRNISRFPAMTGDIDLDYTPGTWTFSLTSSLQGRMYIDYNSEDDGATSKIKKTNTFMIFNCRAAKRFGTCTVYAGAKNIFSYIQDEKHTDDAAFMYAPVYGATWYVGLSVKL
>NZ_CP054011.1|WP_004360971.1|1395475_1396474_+|SPFH-domain-containing-protein
MGLKDIFKRQLRTVIEWKEQKPNLLFHQLETTTDEIKDASKLIVAPGQGCIIVYDGKVKGVLTEPNIYEMETSNHPFITSLLNLAQQTESEHKMRFYFFRTTKMVNILWGTPSPIKYFEPEYKLPITLGACGNFSIVISDPEKMFVTLLGPISDYYSQDVQELVSSRIMTPLTTFLAEKAYTYREVDTHLMEMSEDLKNKTAEELERLGLTLTDFRINSVTFDEDTRERIGRIANMTTEKQAAAEVDLDYVSMQKLDALRDAARNEGGLAGAGLQMGAGLQLAQDIFKTQGKENSREGEITDRLRKLKILFNEQLITEEEYEKKKNEILSKL
>NZ_CP054011.1|WP_081445996.1|1396470_1396806_+|transporter
MKKVIIPALTILIVNIIVGLLLSSYPLANMLFTSIAILVNTLLTVILFLFCAESTHRLSLGFIFTLIGIIEYFSGLIAPGRLTDNWWVIMFVVLTAIQAILVFLSLYYKKK
>NZ_CP054011.1|WP_004360972.1|1396826_1398188_+|hypothetical-protein
MGTRIKPIKCPNCGSEKHTQKDDKCYLCQSCGTEFYIDDDDINININHHFDYIPTSNDTTETGKKIGIYFFIAIAIACAFILLPIIFSSTEKTSSKLFQKDSIDVNDDIYMAVTMSHKGNPCLFYIVNRDFSSDRDNDTKHVDGVYYGFRDIKTGKTLAEQLLVSEKAKNSYNISLYNDNIRYFNQAHRWFLINSERYIFEIDPEQLTMRDVSKSLFKNKNAMSTGISNAQLLYNEYGEGIKIVNNLAEMYYYFPGTDRLYTEDAFNYAKDLPPSELNGELRDSIYYCFEKKNANSSTDKGGKYRLLKIHFKYHLGDPQNGYNFDDVTNTFWVNDGRLVSDRPITDWFTAFNAKIIYQDANYILISYNPNLSETSMPVFQLRSTKGNILWTQASEEPIYDVDFCTRSNGQIWFEGEVRYPDNPTQYKVYSLNIDNGKLTCHFTLPEVHKIPAK
>NZ_CP054011.1|WP_004360973.1|1398344_1399106_+|hypothetical-protein
MRTKYIMMLLLCFFSLQTNAQTEKYVEKYDNGQIKKIYYRNKIWGYREGSCINYAQDGTLYSELNYQEGNLHGTLKFYNKFGKIEAIINYDSGRLEGKSTMYHPIQSADETPTIYFTQIYHDDKLDGMTYEYDKNGKNIIRRARYSHGICMADTTITNNGVIYKYRSYDSDYEDPMISRFVPFKKASATPNKSKTKSQKRTAITRATHSSSSNSTKTTVSSNTLPTQQTKKQATTQERKSRLKVNKDGAIEFE
>NZ_CP054011.1|WP_004360975.1|1401195_1401411_+|hypothetical-protein
MNKMQINRVYQRPEIKVIYVSIDSSILETSYPGDHQKGEHKTGPLEESSTGAKRSFFFRISEESTPTKWEE
>NZ_CP054011.1|WP_004360976.1|1401450_1402989_+|hypothetical-protein
MNIRLYYQWTMAALLLTAVGCSNDDIQTANITNTDKETTEIALTSFVTGEESTTRTSLNYNTRDFYWETGDKIFVKDDANTFKQSSNTVSATNVLTFNFNMPGTYTNNKYRVYYPGANGTGNNVTIASEQEQNGPDNTLHFGVSGDCGSDEAIRQPNGQYKFKLKHAAAYLCFNPNYDHALTNVYVTKIEVTADKNIAGAYTLNTNGELTGSGNTKTIKLTPKASGSNDSFIMQNNASGTSCETGQMYMVIMPGRYKLTVKYYVKDKDTNVSGAITKTFGEFTYAPNGYYDMPATLSIRSYGDDYYMWDAKQEYWYGYKADQPKIENVPGTNFPTSSDADRWYNAATFPTAASNKAKDCPNINELFWYCKKGDPHWDNTTLWSVWGHLYTGGIWLKKASVIAQENSKTTAYLKTASPDDGQNRANKKVFETPPSQAVTQGTPSKLNDYFFLPAMGRYAGGKLFYFRTCGDYWTSTPYPYNSKISYNLHFDNGTLTVSNTSNWENGYKLWKTE
>NZ_CP054011.1|WP_004360978.1|1406883_1407597_-|DUF4919-domain-containing-protein
MRKLFAFMLLLLPLAVSAQTDKTFMSVNWDKIKAEVNANPQHVQQLVDILINVDADTTLTAEDKILAVYGRTYLNNGRDMFMELDMSKARNEGKFDVAATLADKVLASNPLNTNAIVSKIYHFRKLSTTEPDKSWMLSDSLKVYSVRLSRILDTIFMTGDGSKEHPFSVTSVGDEYNLVYFFFGIPKVNSQMVVGSCDRLVLGETNENYTSSDIYFDVKRVFEIERSMFESQGGKGK
>NZ_CP054011.1|WP_004360979.1|1407743_1409285_-|YifB-family-Mg-chelatase-like-AAA-ATPase
MLVKTFCAAVNGMEVTTVTVEVSITRGVLFHLTGLADGAVKESHDRIAAALLNTGYKFPVADITANLAPADLKKVGSSFDLPLAIAILSANEKMSCDRLREFMLVGELSLDGTLQPVKGILPIAIKARAEKFKGIIVPKANEHEAAVVDTLEVYGMDNILQVIDFLNGTSNPEPCFVDTRKEFYEHQYAFDLDFADVRGQENVKRALEVAAAGGHNLIMVGPPGSGKSMMAKRLPSILPPLSLSESLETTQIHSIAGKLRRDTGLITQRPFRSPHHTISEVALVGGGANPMPGEITLAHNGVLFCDELPEFNKHTLEVLRQPLEDRHITISRAKYTVTYPCSFMFVASMNPCPCGYFADPTHHCVCTPGQIQKYLAKISGPLMDRIDIQCEIAPLPFKDISQATPGEPSAAIRERVIRARAIQTDRFSSYRNIHCNAQMSERMIHEFAEPDEASIKLLRDAMERLKLSARAYNRILKVARSIADLEESEAVQVQHIAEAIGYRNLDRSDWAER

Crispr_ID: NZ_CP054011_6

• CRISPR_ID: NZ_CP054011_6
• CRISPR_location: 1592377-1592494
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_6

Consensus_repeat	Method
CACAAGCTAAGACTCCTCCCCCTTCGGGGA	CRISPRCasFinder

spacers of NZ_CP054011_6

>6.1|1592407|58|NZ_CP054011|CRISPRCasFinder
AGTTAAATGGGGTTCTACAAGCTAATATTCCTCTCTTCGGCGAGGTTAGGTGGAACTT

CRISPR arrays and Neighbor proteins around NZ_CP054011_6

CRISPR arrays

The CRISPR arrays of NZ_CP054011_6

>merge|NZ_CP054011|6|1592377-1592494|CRISPRCasFinder
CACAAGCTAAGACTCCTCCCCCTTCGGGGAAGTTAAATGGGGTTCTACAAGCTAATATTCCTCTCTTCGGCGAGGTTAGGTGGAACTTCACAAGCTAAGACTCCTCCCCTTTCGGGGA

>NZ_CP054011|6|6|1592377-1592494|CRISPRCasFinder
CACAAGCTAAGACTCCTCCCCCTTCGGGGA	AGTTAAATGGGGTTCTACAAGCTAATATTCCTCTCTTCGGCGAGGTTAGGTGGAACTT
CACAAGCTAAGACTCCTCCCCTTTCGGGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004358991.1|1593537_1594368_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004358997.1|1584592_1586605_-|alkaline-phosphatase-family-protein	unknown	unknown	gnl|CDD|293739
NZ_CP054011.1|WP_004358990.1|1594472_1595474_-|cysteine-peptidase	unknown	unknown	gnl|CDD|238328
NZ_CP054011.1|WP_036885751.1|1597144_1599442_-|ribonuclease-R	unknown	unknown	gnl|CDD|273947
NZ_CP054011.1|WP_004358992.1|1592515_1593091_+|RNA-methyltransferase	unknown	unknown	gnl|CDD|349970
NZ_CP054011.1|WP_036861976.1|1590460_1591705_+|U32-family-peptidase	unknown	unknown	gnl|CDD|223896
NZ_CP054011.1|WP_004358988.1|1596479_1597136_-|hemolysin-III-family-protein	unknown	unknown	gnl|CDD|224191
NZ_CP054011.1|WP_004358996.1|1586627_1588487_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP054011.1|WP_004358998.1|1583639_1584596_-|lysophospholipid-acyltransferase-family-protein	unknown	unknown	gnl|CDD|153246
NZ_CP054011.1|WP_004358985.1|1600779_1601748_+|phosphatase-PAP2-family-protein	unknown	unknown	gnl|CDD|379588
NZ_CP054011.1|WP_004359001.1|1579152_1579932_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133005
NZ_CP054011.1|WP_004358983.1|1603385_1605863_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|379720
NZ_CP054011.1|WP_004358989.1|1595636_1596452_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_036885752.1|1581177_1583151_-|LTA-synthase-family-protein	unknown	unknown	gnl|CDD|293739
NZ_CP054011.1|WP_004359000.1|1580125_1581127_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NZ_CP054011.1|WP_004358984.1|1601888_1603022_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224586
NZ_CP054011.1|WP_004358995.1|1588587_1589916_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl|CDD|237676
NZ_CP054011.1|WP_004358993.1|1591819_1592236_+|SufE-family-protein	unknown	unknown	gnl|CDD|376883
NZ_CP054011.1|WP_004358986.1|1599708_1600698_+|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223528
NZ_CP054011.1|WP_004359002.1|1578293_1579064_-|polysaccharide-biosynthesis-protein	unknown	unknown	gnl|CDD|226297

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004358997.1|1584592_1586605_-|alkaline-phosphatase-family-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	1.53144e-64
NZ_CP054011.1|WP_004358990.1|1594472_1595474_-|cysteine-peptidase	gnl|CDD|238328	cd00585, Peptidase_C1B, Peptidase C1B subfamily (MEROPS database nomenclature); composed of eukaryotic bleomycin hydrolases (BH) and bacterial aminopeptidases C (pepC). The proteins of this subfamily contain a large insert relative to the C1A peptidase (papain) subfamily. BH is a cysteine peptidase that detoxifies bleomycin by hydrolysis of an amide group. It acts as a carboxypeptidase on its C-terminus to convert itself into an aminopeptidase and peptide ligase. BH is found in all tissues in mammals as well as in many other eukaryotes. Bleomycin, a glycopeptide derived from the fungus Streptomyces verticullus, is an effective anticancer drug due to its ability to induce DNA strand breaks. Human BH is the major cause of tumor cell resistance to bleomycin chemotherapy, and is also genetically linked to Alzheimer's disease. In addition to its peptidase activity, the yeast BH (Gal6) binds DNA and acts as a repressor in the Gal4 regulatory system. BH forms a hexameric ring barrel structure with the active sites imbedded in the central channel. The bacterial homolog of BH, called pepC, is a cysteine aminopeptidase possessing broad specificity. Although its crystal structure has not been solved, biochemical analysis shows that pepC also forms a hexamer. .	5.51929e-08
NZ_CP054011.1|WP_036885751.1|1597144_1599442_-|ribonuclease-R	gnl|CDD|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
NZ_CP054011.1|WP_004358992.1|1592515_1593091_+|RNA-methyltransferase	gnl|CDD|349970	cd18097, SpoU-like, SAM-dependent rRNA or tRNA methylase related to SpoU. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	2.71497e-65
NZ_CP054011.1|WP_036861976.1|1590460_1591705_+|U32-family-peptidase	gnl|CDD|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	3.08222e-88
NZ_CP054011.1|WP_004358988.1|1596479_1597136_-|hemolysin-III-family-protein	gnl|CDD|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	6.06605e-47
NZ_CP054011.1|WP_004358996.1|1586627_1588487_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.41514e-160
NZ_CP054011.1|WP_004358998.1|1583639_1584596_-|lysophospholipid-acyltransferase-family-protein	gnl|CDD|153246	cd07984, LPLAT_LABLAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.	1.46031e-38
NZ_CP054011.1|WP_004358985.1|1600779_1601748_+|phosphatase-PAP2-family-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	7.83129e-10
NZ_CP054011.1|WP_004359001.1|1579152_1579932_+|glycosyltransferase-family-2-protein	gnl|CDD|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	4.4778e-59
NZ_CP054011.1|WP_004358983.1|1603385_1605863_-|TonB-dependent-receptor	gnl|CDD|379720	pfam14905, OMP_b-brl_3, Outer membrane protein beta-barrel family. This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.	1.28954e-69
NZ_CP054011.1|WP_036885752.1|1581177_1583151_-|LTA-synthase-family-protein	gnl|CDD|293739	cd16015, LTA_synthase, Lipoteichoic acid synthase like. Lipoteichoic acid (LTA) is an important cell wall polymer found in Gram-positive bacteria. It may contain long chains of ribitol or glycerol phosphate. LTA synthase catalyzes the reaction to extend the polymer by the repeated addition of glycerolphosphate (GroP) subunits to the end of the growing chain.	2.81738e-51
NZ_CP054011.1|WP_004359000.1|1580125_1581127_-|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.19953e-39
NZ_CP054011.1|WP_004358984.1|1601888_1603022_-|ATP-binding-protein	gnl|CDD|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	7.85636e-08
NZ_CP054011.1|WP_004358995.1|1588587_1589916_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl|CDD|237676	PRK14329, PRK14329, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NZ_CP054011.1|WP_004358993.1|1591819_1592236_+|SufE-family-protein	gnl|CDD|376883	pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export).	3.22527e-67
NZ_CP054011.1|WP_004358986.1|1599708_1600698_+|NAD(P)-dependent-oxidoreductase	gnl|CDD|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	4.67841e-53
NZ_CP054011.1|WP_004359002.1|1578293_1579064_-|polysaccharide-biosynthesis-protein	gnl|CDD|226297	COG3774, OCH1, Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane].	5.30309e-17

Protein sequences

>NZ_CP054011.1|WP_004358993.1|1591819_1592236_+|SufE-family-protein
MTINEAQDAVISEFEDFTDWMDKYQMLIDLGNELEPLEEQYKNEQNLIDGCQSRVWLQCDNVDGKLIFTADSDALITKGIIALLIRVLSNHTPQEIIDADLYFIDKIGLRQHLSPTRSNGLLSMVTKIKAYAVGFSLQ
>NZ_CP054011.1|WP_036861976.1|1590460_1591705_+|U32-family-peptidase
MNKNTNDFEIMAPVGSRESLAAAINAGANSVYFGIGKLNMRSHSANHFTIDDLKEIAETCNAKGIQTYLTVNTVIYGEDIETMHEIIDAAKAANITAVIASDVAVMMYCRQVGVEVHLSTQLNISNIDALKFYAQFADVAVLARELNMDQVKEIHEQIIKQNICGPKGQPIRIEMFCHGAFCMAISGKCYMSLHDSNRSANRGACTQICRRSYTVTDNETGNQLEIDNKYIMSPKDLKSVRFIDKMMDAGVRVFKIEGRARGPEYVHTVVSCYKEAIESVLDGTFTEEKKDQWDERLSTVFNRGFWDGYYQGQKMGEWTKDYGNKATEKKVLIGKVIKYFSRLGVAEVAVEANTFVKGEKLLITGNSTGAMFLNAEEIRYDLNPVDKAEQGWRVSIPVPDKVRPNDKLFKLVTK
>NZ_CP054011.1|WP_004358995.1|1588587_1589916_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MKKLYIETYGCQMNVADSEVVASVMKMAGYDVCENEDEADAIFLNTCSVRENAENKIYNRLEALHAEQKKGRDLILGVLGCMAERVRDDLIQNHHANLVCGPDSYLNLPDMIAQCENGTNALDIELSTTETYRDVIPQRIGGNRVSGFVSIMRGCNNFCHYCIVPFTRGRERSRDVESILKEVKDLHDKGFKEVTLLGQNVNSYGLLPNGKRPENGVSFAELLHKVAQSVPDMRVRFTTSNPEDMTEDIIEAVATEPNLCNHIHFPAQSGSNSVLKVMNRKYTREDYLEKVAAIRRLVPDCGLTTDIFIGYHNESEEDFQQTLSLMREVGFDSAFMFKYSERPGTYAAKHLPDNVSEEEKIRRLNELIRLQTEISAEQNKKDEGKEFDILIERFGKRSREQLMGRTPQNKAVVMPRGNHHIGETVRVRITGSTSATLFGEEV
>NZ_CP054011.1|WP_004358996.1|1586627_1588487_-|ABC-transporter-ATP-binding-protein
MKEFIQVLRRFIPPYKKYLVLSIIFNILSAFLNIFSFATLIPLLQILFKVDAGTGATRAMSWSEGSFKEVLSNNADYYTQIYITSWGPTTVLLAIGLILAFMTFLKTGAYFLSSASIIPIRTGVVRDIRNQLYEKITSLSLGFFSEGRKGDIIARMSGDVQEVDNSIMSSIDMLFKNPVLIIIYFTTLLVISWQLTLFTLIFVPIFGWFMGFVGRKLKQNSMTAQKLWSDTMSQVEETLGGLRVIKAFCAEGMMNERFDKINSEYRSDIMRVNIRQQLAHPMSEFLGTVMIVVVLWFGGTLVLGESPIISGPTFIYYLVILYSILNPLKEFSRAGYNIPKGLASMDRIDKILQAEVKINDPEKPVHIDSFEHEIEFRHVSFAYTDGKDDEGKPELHWVLKDINLVIPKGKTVALVGQSGSGKSTLLDLIPRYYDVQEGEILIDGINIKDLGVHDLRQLIGNVNQEAILFNDSFKNNISFGVNATDEAIVEAAKIANAHEFIMHSERGYDTNIGDRGGRLSGGQRQRVSIARAILKNPPILILDEATSALDTESERLVQDALYKLMKTRTTIAVAHRLSTIKNSDEICVLHEGEIVERGTHDELMDIEGYYKKLHDMQEI
>NZ_CP054011.1|WP_004358997.1|1584592_1586605_-|alkaline-phosphatase-family-protein
MKGLLKTTFGSPIALVFNLLLAYAIFFVARLTYFFVNYSYFIDGLSASSLWMWVRGSLLFDTTAILYTHILYIVMMLLPLWRKENQAYHRLCKWVFMVVNALSLAINLADSVYFPFTLRRTTTTVFREFDNENNIAGILFHNAITHWYLFLIFILILWLANKLYVMPRTDYRSYQSLRQRLVYAAQLFICFAVAAVLTVAGCRGGLQSGVRPITISNANQYVERPTDCALVLNTPFALIRTIGKSDFSVPDYFPSLAAAREVYDPVYWMQYKEPNPASGVRLPNKKNIVILIVESFGREYIGAFNRDFFDGKYKGYTPNVDKLIDKSLVYRFSYCNGRKSIDGMPSILCSIPRFGEPFILTPASMNNYTGMPGLLSKWGYQTAFFHGANRGSMGFLAFANKIGFQHYYGRQDYDEDPRFGGDKDFDGNWGIWDEPFLQYYCAKMGEMKQPFMTALFTVSSHDPFVVPEKYKNIYKEEHLPIQKCIRYTDMAIGKFFESASKQPWFKNTIFVLTSDHTNQSDHEQYKTDIGGFCSPIIIYDPSGEIKPGRVDGVAQQIDIMPTLLFHIGYNATPYLAFGKDLLHTPAKETWAVNYLNGIYQYIKYGYVLQWDGKQTKAIYRVTDALMKHNLLGHVPEQTKMERELKAIIYQYMYRMVHDKMHPTINNPEDQ
>NZ_CP054011.1|WP_004358998.1|1583639_1584596_-|lysophospholipid-acyltransferase-family-protein
MKRALNKTLYIIAYGFWYLVALLPFPVLYLLSDGLYLLMSRVVKYRHKVIWTNLKNSFPEKTDDELRQIEQGFYRWFCDYIAETLKLMTMSKMQLMKRMTFTGTEELNRVLSEGKSAAVYLGHLGNWEWITSLPYWVNNTLCCQLYHPLENEYFDRLFKFVRERQGALCIPMQESLRKIIQFGRNGKPLVVGYISDQAPFWWSIHHWVQFMNQETPVLTGGERIVKHMSQVFVYGDVTRTRRGHYNCEFRIIREETKGLPDYEITDLYFKELEQSIRHQPEIYLWSHNRWKRTRARFDEYFEEIDGKVRLREGKEMIY
>NZ_CP054011.1|WP_036885752.1|1581177_1583151_-|LTA-synthase-family-protein
MYKNLTYLIKHSAVILVILFFVRICFAIAFVPMSIISNNLAVFPHLLFNVFRFDLQVVCYVLLLPTVLTFIFAAIRKSWTECVLSRFRRLYFSIISTLLLAISGIDIGFYDNFNSHINITFFDFFNEGPMGLIQTIWEEYHCVYEAIAFLLILSPVLLLIRRIELSKSSSRHPLHSTSRQRLSRFEITKLSATILLYLTFLVIGLRGSVWRFPLQIEDTFVSNQKLLNDLVPNAIYMLKKAYKEKNNAFKIAKTDDLLHEYKFKSLQEALDLYTDGKVKMANNDTLRALQHALFEEVGDSLKQPQPNIVIIYSESWSNYLFNLQQKNAEMYFGLERHFKEDLLFRNFQSVQNGTVASLENLYVSTPFPRFFASAYRFKTLPTSIALPFKASNYTTTFMSGMDAAWENCAEALPHQQFDAVYDKFFILKDYPHATYNSIGVYDEYLFQALLDKLNKPSKKRQMIAVMTTTNHPPFEFPKDLKLPPLPDSFYGKKCFAEHNRKVLDKYLTGFRYYNKALNDFLNRFKASAAAKNTILVITGDHNVRVILNHDVIDKRYEHSVPLYVYLPPYLRKEAYNKLTNRWGSHDDILATLAPFAFRNTKYFKMGKNLLDTSVSDSTYYSANVDQIEAIPTYQKKAERLTAARNFLRLVYFAKLFR
>NZ_CP054011.1|WP_004359000.1|1580125_1581127_-|glycosyltransferase-family-2-protein
MISIITPVFQSERYLEKLINSILNQTYCDWELLLIDDGSTDGSAEICDRYAHKDNRIRVFHKANGGVASARNQAMDMATGEYLAFADSDDWVEPCWLERLYKTAKEQEADIVVSDYYEEYPQKTIMRSKDDDDVIVLNRKDALFLTFQDKITSYLWSMLIRRDIAQERFAPYRAFEDYATLFAWMFQANRVVLLHTPLYHYRQYAYSCLHSNMKQNITDYIEATITRYKLVKESSFLQDNISQFNAAYIYSLVKGLKDIVRSPYDNDFKQKLLKKVSDEIRTIELPSPYKMLGFKYYVRYTLLCKSLKLFKHIVGGTAVFSFNRSRKKVELFS
>NZ_CP054011.1|WP_004359001.1|1579152_1579932_+|glycosyltransferase-family-2-protein
MEKKEISVVINTYNAEKFLQRVLDSVKGFDEIVICDMESTDHTVEIAQRAGCKVVTFPKGNHTCVEPARNFALQSAKGPWLLVVDADELVTPELRIYLYQHINKPNCAKGLYIPRQNRFMNTPKKGFSKDYQLRFFIREGTFWPPLIHTIPQVQGKVEYIDNHLYNVKLLHLAENYLADMLEKCNRYTTNEVLKKKGKNYGVGALLFRPFWRFFKSYFMNGEIRNGVTGFIDSVMTGFYQFMIVAKIIESKIKKQTEDE
>NZ_CP054011.1|WP_004359002.1|1578293_1579064_-|polysaccharide-biosynthesis-protein
MIPKVIHYCWLSNDPYPDKIQKCMDTWKKVLPDYEIKLWNTENFDMSKAPTYVREAFEQRKWAFAADYIRMYALYTEGGIYLDSDVKVLKSFDEFLNYNFFTSLEYHPKQIEMTGAMDMIDDEGNRIKDGFVSGIQIQAAVMGSEAGCQFVKDVLDDYEKREFIYPEGPRLVCKGVISPFVYARVMEKYGFKYLDKDQPLEDNMMVFRSEIFAGNKYEATPASYAIHYCAHSWKRTPVEKFNRWLKRNIPCLFPKK
>NZ_CP054011.1|WP_004358992.1|1592515_1593091_+|RNA-methyltransferase
MRKLRTIEMNRLSLEEFKEADKLPLIVVLDDVRSLHNVGSVFRSADAFRVEAVYLCGITATPPNAEIHKTALGGEDSVDWRYFERTEDAIEELHHQGVFVYSVEQVEGSTKLQELNTENPTNHQHPTPNTQHPVIHYAIVLGNEVKGVKQSVVDMSDGCLEIPQFGTKHSLNVSVTTGIVIWEFARQLLIK
>NZ_CP054011.1|WP_004358991.1|1593537_1594368_+|hypothetical-protein
MKKVLLYLLALPVIMLLLASCHSEEDDFIDKPDPKSLIIKGVAKTPDGQPIPNIELKLDYTIMSALYSIKVYHKAKATTDKDGNYIMFFNLNDKELKSLTTYSPEEGFVYHLQMTLDLSKLDDKVYLLPTDITAVRPLSERKLFYDAYGMPGRLQQGQVYEQNILIPRKQLAKVRIETNGAINEKDSFAICNKVRYGIESQIPNGFNGERGYLMFYQPIKLKNTHSQTVQISCAAEEDSKLSLYRLPDGEFNYKEYSSEVEVPVMQAGGELILRTH
>NZ_CP054011.1|WP_004358990.1|1594472_1595474_-|cysteine-peptidase
MKKSIFIFLACLVLVSCGQQRSNISFPEEKFTVDLRLPTTPVKGQGLSSLCWVYGMLATLETEHIIRGDSINLSPDYVARMYLSEQANRRHLLPNKVVQKEADITTRGMCTMALDLIQTYGLQHYDAYRHKPDMDYNVLCRKLDKGNDAEKLLDKYIGPLPKQVFILGALYTPLEFAHSVCTDDEYVALTSFTHHPYGQRFPLEVPDNYFHDTFLNVPLDTMMNRIVQSLRAGHPVCWEGDISEPGFLFGNGFAVLKNEDKKVTAERRQTSFEAHRTTDDHVMEIVGLAHDQHGRRFFLCKNSWGTANRYHGFMFLSENYVRMKTIAVVLRAI
>NZ_CP054011.1|WP_004358989.1|1595636_1596452_-|hypothetical-protein
MFKRSFLLSIILILAVVNTQAQERQYTRLKGYYRVYQSTNSMLSYFIDGMMEFYIPLSDTAIEASEGKKGSPFVERKFLGERRRKAPKANGDDTFVRISLPNLERQTLLKSIDSEEYSTRNNGDVYRWADKCGKISKEKRKINGKIEVVTTLEMDELVGQPKHEIDMSQLRMYGIVARMTQYDESESYLSNNLLLASQKHQTFFAHYRGEDDDERIDVWSEFYVSDRMTITESELKRIKKEKNSVWTFSIPAVVPPLDKEVAEAWTKMVEY
>NZ_CP054011.1|WP_004358988.1|1596479_1597136_-|hemolysin-III-family-protein
MRRKIFFSHKEELWNSWSHSGGIVLGVVFGTIFLVWCSKERSGWATAGVILYLVGMLFSYITSTVYHALSAHSVWKERLRKWDHAAIYWHIAGSYSPITLIALRNQGAWGWGLFAFVWLCAILGTISSFRKLRDHSNLETLTFIGMGLSVLVAFKPLVDALETQSLVWIFAEGVMYITGALFYSLNKRKYMHTVFHFFVLAGSICHIIAVWGILKEYL
>NZ_CP054011.1|WP_036885751.1|1597144_1599442_-|ribonuclease-R
MRKEKKSSKRLTKKQLAEKLMSFFQTQPDETFSFKQIFHALKLTTHPAKMLAIDVMEELAWDDFLSKVGESAYTLNTKGQVQEGTFIRKANGKNTFLPEDGGTPVFVSERNSMAALNGDQVRVQFMARRQNHIKEAMVIAILQRKKDTFVGRLRVEKDIAFLVTQENLFIHDILIPKKKLKGGKTDDRALVKITKWPDADHKNLVGEVVDVLGEAGDNDVEMNTILAQYGLPYKYPKRVEDAAEKISAEITAQDYAEREDFRDVWTCTIDPRDAKDFDDALSIRKLESGLWEVGVHIADVSHYVKEGDIIDREAQQRATSVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSCIFNLDDEANVKAYRIVHTVIKSNRRYAYEEAQQILEDNGVIDGTGEPAPNPGKAGYKGENAEQIITLDRLAKLIRGRRMKAGSVKFDSEELHFDIDEKGKPIRCYFKRSKDANKLIEEFMLLANKTVAESVGIVKKGKKAKTLPYRVHDNPDPQKFENLREFTAKFGYKLKSASTKGATARALNKLMDEVQGKREEKVIQTIALRSMMKAKYTTHNIGHFGLAFDYYTHFTSPIRRYPDTMVHRLITRYQNGGRSANKDHYEELCEHCSDMELVAQNAERDSIKYKMVEFMSEHIGECYDAHISGIQSFGIYAEIDENHCEGMIPMRDLDDDYYDFDEKNYCLVGRRRHHVYQLGDPIRIQVAKADLERRQLDFALDDGRPLKAKQTAAEYAVNRKNDRKSSKRGSKSRRRK
>NZ_CP054011.1|WP_004358986.1|1599708_1600698_+|NAD(P)-dependent-oxidoreductase
MKKILITGASGFIGSFIVEEALRRGMETWAVVRRTSSREYLQDERIHFIELDFSSVDKLKEQLSGHQFDYVVHAAGVTKCLNKEDFFRVNRDGTRNFVEALQALNQPLERFVFLSSLSIFGAIREQQPYKEIEPTDTPQPNTAYGKSKLEAEQLLPSSFPYIILRPTGVYGPREKDYFLMAKSIKGHSDFAVGYKQQDITFVYVKDVVQATFLALDHGKIGSAYFLSDGKVYQSTTFSDLIHEELGRPWWIRITAPIWVLRVVTFFGDLIGHATGKISALNNDKYQILKQRNWRCNIRPAIEELGYKPEYDLKRGVKETIEWYKKEGWL
>NZ_CP054011.1|WP_004358985.1|1600779_1601748_+|phosphatase-PAP2-family-protein
MKQFIIDLFKLEKKPVKGLMAYEWVVMAYLVLTLIVIFFMYTTINNPQAMIFGRLRIVALTAAMWVVYRLAPCRATHFLRVGVQLGLLAWWYPDTFEINRHLPNLDHLFAQWEQDLFGCQPALLFSKALPGHLFSELFDMGYAAYYPMIAATAVYYFGWYYKEFNRATFIILSSFFIYYIVFIFVPVTGPTFYYKAIGLQNVTAGIFPNVHDYFNHHQECLPSPGYTDGIFYHLVEDAKAAGERPTAAFPSSHVGVSTICMLLLWHDRNYKLLAILAPFYLLLCCATVYIQAHYLIDAIAGFITAVILFAILLRISRKMITA
>NZ_CP054011.1|WP_004358984.1|1601888_1603022_-|ATP-binding-protein
MCKKFVYGVAVSDYNFIGREVETNRLMNNFRGGINTILMSPRRLGKTSLVMRVCEKMKSEDIITIYLDIFGCKSEYDFYNRLASEVLKQTASKQSMWLEEAKEFLYRLTPKISFSPEPNSDFAISLGITPKTHTPEEVLEMVEKIAIKKGKQIVVCIDEFQQIGEMTDSKHVQARLRSVWQHQKHVSYCLFGSKHHLMSSIFLHRSMPFYQFGDLIVLGKIPSAEWVEYIVSHFADGKRTISSALAEEICSFTDNYSAYVQQLSWLVYTQKEEGETVDEIDIKQATDDLLATNEVLFMQMVEPLSEYQLNFLRALCSGVTKNFGLAKIREKYQLGSYSNISRLQKALFDRDLIEKRGMELAITDPVFAKWFQRKMMF
>NZ_CP054011.1|WP_004358983.1|1603385_1605863_-|TonB-dependent-receptor
MKINRLIVTLGMMAIAITAHGQTSTISGVLLDSLTHEGEPYATIRVYKGKKSETPVAMSVTEKDGKFSQKVTGQGSYLVSFTSMGRKEILRKVQLTATGGTINLGNLLVQDDTKQLKDVEVVAQKPLVKMETDKMTYDVQSDNDVKTNTVLDMLRKVPMVTVDGQDNITVNGQGSFKVYVDGKPNVMFSSNPSQIFKAMPASAVKSIEVVTNPGAKYDAEGVGGVLNIIMNTGDGKSKAKMNGYNGSVALTLGNNGSRTTTFFSGQQGKLTYSANVMGAKFKSNGTETEMRRTSSDGSAMSYWQKGNTKINFTMANISLGYELDSVSNIGATFGLTGYAMKNDGHPTTTFSGGAYGTGFTYGNEMTMENKNKSFNGSVDYQRFFNKERTSSLTLSYLFTTSPAENNNRRIYDALPAGVTIPLSDLYSTAKTRGTEHTVQVDFTTPLGKGQTLSTGLKFISHRNSSDSKFYDITGGTEVYNAANSVNYKNTQSILAEYAEYSATMGKFGAKAGLRYEHTWEKVHFIVGSGSDFKKNYGSLVPSASFTYNISGGVNLGLNYNMRISRPGVSYLNPYIDRSNPTVLSYGNPDLSVEKSHNVSLVFNYFTPKFMMNMTLGEAFANNQIEQYSFMNGTVLNTTYGNIVRSRWTNFSTFMNYAVTPKTRIMLNGSFDYGDIRSQQLGEYNHGWQASAFLGVQQTFPWKINWSVFMGGLTKKYLLQGHNGGFNMFTSTLSKSFIKDKLNLSFMYFVPLTGKMHIKQYSHGANFENHMNITIPAQHVALTLTWNFGNTKKQFQTHKSNISNDFQEKKNDQQMNGVGMGAGTGM

Crispr_ID: NZ_CP054011_7

• CRISPR_ID: NZ_CP054011_7
• CRISPR_location: 1843329-1843428
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP054011_7

Consensus_repeat	Method
TTGTCTTTAAGCGTCATCAGTAATCATAATTATG	CRISPRCasFinder

spacers of NZ_CP054011_7

>7.1|1843363|32|NZ_CP054011|CRISPRCasFinder
CCCTTTGAACATAAAACTTTGAGCTTTGAACC

CRISPR arrays and Neighbor proteins around NZ_CP054011_7

CRISPR arrays

The CRISPR arrays of NZ_CP054011_7

>merge|NZ_CP054011|7|1843329-1843428|CRISPRCasFinder
TTGTCTTTAAGCGTCATCAGTAATCATAATTATGCCCTTTGAACATAAAACTTTGAGCTTTGAACCTTGTCTTTAAGCATCATCAGTAATCATAATTATG

>NZ_CP054011|7|7|1843329-1843428|CRISPRCasFinder
TTGTCTTTAAGCGTCATCAGTAATCATAATTATG	CCCTTTGAACATAAAACTTTGAGCTTTGAACC
TTGTCTTTAAGCATCATCAGTAATCATAATTATG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004358760.1|1845794_1846364_-|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|153229
NZ_CP054011.1|WP_036885716.1|1851699_1853148_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_036885723.1|1829154_1831491_+|type-I-DNA-topoisomerase	unknown	unknown	gnl|CDD|236048
NZ_CP054011.1|WP_004358762.1|1844104_1844617_-|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274376
NZ_CP054011.1|WP_172891407.1|1840847_1841627_-|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NZ_CP054011.1|WP_004358759.1|1846498_1847389_+|NAD-kinase	unknown	unknown	gnl|CDD|179352
NZ_CP054011.1|WP_004358754.1|1853161_1853689_+|hypothetical-protein	unknown	unknown	gnl|CDD|379226
NZ_CP054011.1|WP_004358764.1|1841623_1842898_-|glycosyltransferase	unknown	unknown	gnl|CDD|340851
NZ_CP054011.1|WP_004358770.1|1832249_1834142_+|biosynthetic-arginine-decarboxylase	unknown	unknown	gnl|CDD|235427
NZ_CP054011.1|WP_004358758.1|1847536_1849216_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224055
NZ_CP054011.1|WP_004358773.1|1828539_1829076_+|NUDIX-domain-containing-protein	unknown	unknown	gnl|CDD|240037
NZ_CP054011.1|WP_004358767.1|1838237_1839455_-|anaerobic-sulfatase-maturation-protein	unknown	unknown	gnl|CDD|237489
NZ_CP054011.1|WP_004358757.1|1849344_1850274_+|redoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239264
NZ_CP054011.1|WP_004358763.1|1843635_1844115_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_036885722.1|1837099_1838104_+|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NZ_CP054011.1|WP_036885718.1|1845079_1845772_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
NZ_CP054011.1|WP_036885717.1|1850894_1851392_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_004358766.1|1840243_1840666_-|hypothetical-protein	unknown	unknown	gnl|CDD|153354
NZ_CP054011.1|WP_036885771.1|1831585_1832161_+|shikimate-kinase	unknown	unknown	gnl|CDD|140006
NZ_CP054011.1|WP_004358769.1|1834728_1836825_+|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl|CDD|236794

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004358760.1|1845794_1846364_-|DJ-1/PfpI-family-protein	gnl|CDD|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	9.30996e-59
NZ_CP054011.1|WP_036885723.1|1829154_1831491_+|type-I-DNA-topoisomerase	gnl|CDD|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NZ_CP054011.1|WP_172891407.1|1840847_1841627_-|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	4.03955e-70
NZ_CP054011.1|WP_004358762.1|1844104_1844617_-|RNA-polymerase-sigma-factor	gnl|CDD|274376	TIGR02985, Sig70_bacteroi1, RNA polymerase sigma-70 factor, Bacteroides expansion family 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.	2.94265e-31
NZ_CP054011.1|WP_004358759.1|1846498_1847389_+|NAD-kinase	gnl|CDD|179352	PRK01911, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	2.05321e-141
NZ_CP054011.1|WP_004358754.1|1853161_1853689_+|hypothetical-protein	gnl|CDD|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	0.00879727
NZ_CP054011.1|WP_004358764.1|1841623_1842898_-|glycosyltransferase	gnl|CDD|340851	cd03825, GT4_WcaC-like, putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.	2.00667e-129
NZ_CP054011.1|WP_004358770.1|1832249_1834142_+|biosynthetic-arginine-decarboxylase	gnl|CDD|235427	PRK05354, PRK05354, biosynthetic arginine decarboxylase.	0
NZ_CP054011.1|WP_004358758.1|1847536_1849216_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.05096e-108
NZ_CP054011.1|WP_004358773.1|1828539_1829076_+|NUDIX-domain-containing-protein	gnl|CDD|240037	cd04681, Nudix_Hydrolase_22, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	6.99355e-56
NZ_CP054011.1|WP_004358767.1|1838237_1839455_-|anaerobic-sulfatase-maturation-protein	gnl|CDD|237489	PRK13745, PRK13745, anaerobic sulfatase-maturation protein.	0
NZ_CP054011.1|WP_004358757.1|1849344_1850274_+|redoxin-domain-containing-protein	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	6.89948e-29
NZ_CP054011.1|WP_036885722.1|1837099_1838104_+|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	3.37655e-39
NZ_CP054011.1|WP_004358769.1|1834728_1836825_+|ATP-dependent-DNA-helicase-RecG	gnl|CDD|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NZ_CP054011.1|WP_036885718.1|1845079_1845772_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	7.91758e-102
NZ_CP054011.1|WP_004358766.1|1840243_1840666_-|hypothetical-protein	gnl|CDD|153354	cd07670, BAR_SNX18, The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 18. BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions. Sorting nexins (SNXs) are Phox homology (PX) domain containing proteins that are involved in regulating membrane traffic and protein sorting in the endosomal system. SNXs differ from each other in their lipid-binding specificity, subcellular localization and specific function in the endocytic pathway. A subset of SNXs also contain BAR domains. The PX-BAR structural unit determines the specific membrane targeting of SNXs. SNX18 is localized to peripheral endosomal structures, and acts in a trafficking pathway that is clathrin-independent but relies on AP-1 and PACS1. BAR domains form dimers that bind to membranes, induce membrane bending and curvature, and may also be involved in protein-protein interactions.	0.00139542
NZ_CP054011.1|WP_036885771.1|1831585_1832161_+|shikimate-kinase	gnl|CDD|140006	PRK13949, PRK13949, shikimate kinase; Provisional.	1.43271e-78

Protein sequences

>NZ_CP054011.1|WP_004358764.1|1841623_1842898_-|glycosyltransferase
MRILIVNTSEKTGGAAVAANRLKDALNNSGVKAKMLVRDKLTDDITVVSLGHEWRNQWHLLWERFCVFWNLHFSRNHLFEIDIANSGTDITKLREFKEADVIHLSWINQGMLSLNSIKKILCSGKPVVWTMHDLWPASGICHYAHGCYRYENGCGNCPLLPGRGSSNDLSSKVWKRKKAVYHHGNMWFVTCSQWLARQAKRSGLLRGISVRSIPNPIDTHIFEPQDKQKARQQLQLPEDKRLILFVSQRVTDQRKGMDYFIDAIDKMVAEHPEMKDNTGIAILGGHAEELEGKLALPVYPIGYVTDQQRICDVYNAANVFVLPSLEDNLPNTIMEAMACGVPSIGFKVGGIPEMIDHCKNGYVAAERNADDLAKGIHWVLDESDYTALSEAAVGKVLRCYSQRSVAMQYLEVYNEALAYKNFRL
>NZ_CP054011.1|WP_172891407.1|1840847_1841627_-|glycosyltransferase
MITFSVVTITYNAASVLQPTLDSVLMQDYPHVEHIIIDGASTDNTLEIAKAYQQLSNEAENEHVVRIQSEPDEGLYDAMNKGLQQATGDYIVFMNAGDRFPNPDTLDKVVLAAVVGDGEELPAVLFGDTDIIDEKGNFISHRRLSPSERLTWRSFRYGMLVCHQAFYARLDIARSLLYDTTYRYSADVDWCIRVMKEGERQQLLLRNIHAVVANYVREGQTTRHHKESLRERFDVMCKHYGLIQTVLLHAWFAVRSLIK
>NZ_CP054011.1|WP_004358766.1|1840243_1840666_-|hypothetical-protein
MLVALLLLCLSVSAQTEYSGIAGASPGMVRANKQAAAKQANRNSKAANSSNVSKPKTSNNGNANSNNSTYAPLPDNDESGETEVRDGFKTFSRGMSKVIKRETRTMGEVTRKIGADGKKFFKKLGKGISDSFKPDTTTSK
>NZ_CP054011.1|WP_004358767.1|1838237_1839455_-|anaerobic-sulfatase-maturation-protein
MNTIVPFSHPMYIMLKPAGSLCNLRCKYCYYLEKSKLYDDNKNHVITDALLEKFIKEYIEAQTTPQVLFTWHGGETLMRPISFYRRALELQRYYARGRQIDNSIQTNGILLNDEWCRFFKENNFLVGVSIDGPQEFHDEYRRNAMGKPSFHQVMKGIDLLNKHGVEWNALAVVNDFNADYPLDFYHFFKEIGCRYIQFTPIVERIIKRTDGLTLAPGMQEGGELTDFSVTAEQWGNFLCTIFDEWVHHDVGEYYIQLFDATLANWVGVPPGICTMAKECGHAGVMEYNGDVYSCDHFVYPEHKLGNLSQHTIYEMMNSDRQKDFSKMKYRLLPQQCKECKYQFACHGECPKNRFIRDCYGNPGLNYLCKGYYQFFEHVAPYMDFMKNELENQRPPANVMNQVFGK
>NZ_CP054011.1|WP_036885722.1|1837099_1838104_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MTFKKIVRTFALTSLLTLTAHSANAQDLLARQAPIDRRAKALDTMVINRLREAEEIEEPSSELYNDWNNNYAHRGGNLPDVYKIDLRDFHMPTPSRVITSNFGRRWGRRHQGLDIKVYIGDTIRAAFSGKVRVVKYDGNGYGKYIVIRHNNGLETIYGHLSKQIVSPNQTVRAGQPIGLGGNTGRSTGSHLHFETRLAGVALNPALFFDFANQDVTGDYYVFHRNTVAQESERATAARGTSSSLGYSRENIQGKGYQSHSSRQERNYNTDFSSHTPRNEASADNGKIFYHKVANGETLETIAKQHGISIEQLCRQNRIGRLTRVSEGQLLSITK
>NZ_CP054011.1|WP_004358769.1|1834728_1836825_+|ATP-dependent-DNA-helicase-RecG
MDILSQDIMYLPGVGPHRKEILGKELGIHTYRDLLEYFPYKYVDRTKLYLISELSQDMPFVQIKGRILSFEETEMGKRKKRIVAHFTDGHGVCDIVWFNGTKYIYQNYQVNKEYIIFGKPTFFNGRFQFTHPDIDDASQLQLNDMGMQPFYVTTEKMKKAGITSRAVEKLTKMLISKLTEPLEETLPPFITTHLHLISRDAAMRKIHYPKSVDDTQRARVRLKFEELFYVQLNILRYASDHRRKYRGYIFNRIGAQFNWFYSHNLPFELTGAQKRVMHEIRADMASGRQMNRLLQGDVGSGKTLVALMSMLIAIDNGYQACMMAPTEILAEQHLQTIKEFLKGMNLRVELLTGIVKGKKRQEVLDGLIDGSINIVVGTHAIIEDKVQFQHLGMAVVDEQHRFGVEQRAKLWSKSENPPHVLVMTATPIPRTLAMTIYGDLDVSIIDELPPGRKPIQTIHKYDDQMASLYSGIRQQINLGRQVYIVYPLIKESERMDLKNLEDGFEAMQDIFPEFQLSKIHGKMKDKEKEAEMQKFVSGQTQILVATTVIEVGVNVPNASVMVILDAQRFGLSQLHQLRGRVGRGAEQSYCILVTNHKLTKETRKRIDIMCDTNDGFEIAEADLKLRGPGDLEGTQQSGIAFDLKIADIARDGQIVQMAREEAQKIIDDDPTCKKIEYNMLWERLKALRKTNINWAAIS
>NZ_CP054011.1|WP_004358770.1|1832249_1834142_+|biosynthetic-arginine-decarboxylase
MKKWTIEDSQELYNISGWGTSYFGINESGDVYVTPCKDNTQVDLRDVMDELALRDVTPPVLLRFPDILDNRIEKTSSCFEKARKEYDFKAENFIIYPIKVNQMQPVVEEIISHGRKFNLGLEAGSKPELHAVIAVQCQSDSLIICNGYKDQSYIELALLAQKMGKRIFIVVEKLNEIDLIARAAKKLNVKPNLGIRIKLASSGSGKWADSGGDASKFGLTSSELLQALETLDNKGLHDCLHLIHFHIGSQITKIRRIQTALNEAAQYYVNLRKMGYNVDFVDCGGGLGVDYDGTRSASSESSVNYSIQEYVNDCVYTFVDAANKNDIPHPNIITESGRSLSAHHSVLVIDVLETASLPEMSEDFEAKDTDHQLVKDLYDIWDNLDSRNMLEDWHDAEQIREEALELFSHGLVDLKTRAEIEAMYWSVCHEINNLAKNMKHVPDELRNMDKLLADKYFCNFSLFQSLPDSWAIDQLFPVMPIQRLNERPSRNATLQDITCDSDGKISNFVAMGRSSHVLPIHALKKNEPYYLGVFLVGAYQEILGDMHNLFGDTNAVHVSVKDGSYHIDQIFDGETVEEVLEYVQYNPKKLVRQLEIWVTKSVKQGKISLEEGKEFLSNYRSGLYGYTYLE
>NZ_CP054011.1|WP_036885771.1|1831585_1832161_+|shikimate-kinase
MTEHTEEYNPLRIILIGYMGAGKTTVGRALSKELNIPFYDLDWYIESRMRKTVKQIFDERGEEGFRMIEQSMLHEVAEFENVIISCGGGTPCFFDNMEYMNGQAETVYLKAETDVLYKHLLMGKSVRPLLLNKTADEVNLFIREHLKHREPFYTKAKHVLDVSLMDSYDKIQISVNQLCQLLKLNKANSLK
>NZ_CP054011.1|WP_036885723.1|1829154_1831491_+|type-I-DNA-topoisomerase
MQENLVIVESPAKAKTIEKFLGKDYKVMSSYGHIRDLKKKELSIDLDTLNPDYEIPDEKKKVVSELKKSAKAADKVWLASDEDREGEAISWHLCEVLGLDEDKTNRIVFHEITKPAILKAIESPRRLDMNLVNAQQARRVLDRLVGFRLSPVLWRKVKPALSAGRVQSVAVRLIVEREREIQNFNSEPYYRLNAVFAVTSEDGSKNEVKAELNKRFKTHEEALAFLELCKTSKFKVSSIAKKPLKRTPAPPFTTSTLQQEAARKLGFTVSQTMMVAQRLYEAGRITYMRTDSVNLSAFAIEGCKTEIERLYGEDYGKVRKYQTHSKGAQEAHEAIRPTYIDNVSIEGTSQEKRLYDLIWKRTIASQMADAKIEKTTVNISLESEEAKNTTDLQFIANGEVVAFEGFLKVYHESTDDDENSEEFSHALPVMHEGEELERREIVSTERYSQGPNRYTEASLVRKLEELGIGRPSTYAPTISTIQQREYVQKGDRKGEERKYAVDSLLGLKITSKTKKEMAGADKGKLIPTDIGIVVNDFLMGNFPDIMDYNFTAKIEQEFDKIAEGKAEWNKEMKTFYQSFEPEVEKVMNARSEHKAGERELGVDPATGKPVFVKIGRFGPVVQIGSADDEDKPRFSQLPSDKSMETITLDEALELFKLPRNLGQFEGTDVVIGAGRFGPYVLHDKKYTSLPKEEDPLTISLDAAINLIQKKRLQDAQRHLKTFEEDAKMEVMNGRYGPYIAYDGKNYRMPKTLHDKAAELTYEQCMDIVKNAPEPKRKK
>NZ_CP054011.1|WP_004358773.1|1828539_1829076_+|NUDIX-domain-containing-protein
MHVLDKFRYCPVCGSKHFVEQNEKSKRCESCGFEYFLNPSSAVAAFILNEQGELLVTRRKFEPGRGTLDLPGGFCDIGETIGEALIREVREETNLTVKEKHYFCSLPNKYRYSDFDVPTLDVFFVCKVEDETVLKAADDVEEAMWLPLSEVHTEQFGLRSIRQALYDFLQMESKNLKK
>NZ_CP054011.1|WP_004358763.1|1843635_1844115_-|hypothetical-protein
MDYKYIEQLLERYWRCETSLQEEEILRMFFSQEDIPAALLPYRSLFVYEQNEKEMDGLGDDFDQRVLGLIQEDEPVKARVITMRHRLMPLFKAAAVVAIFLTLGNAMQVAFSDGDVHQVSPSTAAVDKPQEGPSVAKADSVVSDTLQHKVQSPVSTITK
>NZ_CP054011.1|WP_004358762.1|1844104_1844617_-|RNA-polymerase-sigma-factor
MKKVSFRNDVLPLKNELFRLALRITLNRAEAEDIVQDTLIKVWNRRYEWENIDSIEAFSLTVCRNLSLDRIKKKENNNDSLEDVKVAEPLTSSNPQDRMIEEDKISLVKQIVDALPEKQRGCMQLRDFEGKSYKEIAEILEISEEQVKVNIFRARQTVKQKYLKLDNYGL
>NZ_CP054011.1|WP_036885718.1|1845079_1845772_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MTSKTSKYAIIVAGGKGLRMGADIPKQFLPVGGKPVLMHTISRFHAYDKDLKVILVLPKEQQTYWKELCEQYHFDEEYQLADGGASRFQSCKNGISMIPTDAIGLVGIHDGVRPFVSCETIARCFDTAQTSKAVIPVLPVTDTLRFIGDSPSGRNVQRSNYKAVQTPQVFDIQLIKKAYEQEESADFTDDASVVERLGQVVTMVEGNRENIKITTPFDLKVAEALLIHNS
>NZ_CP054011.1|WP_004358760.1|1845794_1846364_-|DJ-1/PfpI-family-protein
MAKVYEFLANGFEEVEALAPVDILRRGGVEVKMVSITGSNLVESSHGVVVKADLLFENITDFSDADLLMLPGGMPGSKNLNEHEGVRKALKEQFEKGKRVAAICAAPLVLASVGLLKGKKATIYPGMESYLGEDAEYTGALVQEDGNVTTGAGPAASFPYGYQLLSYFLPAEKVEEIKKGMIYDRLLNS
>NZ_CP054011.1|WP_004358759.1|1846498_1847389_+|NAD-kinase
MAEKKLSFAIFGNASKAFDSLQITEILDYLREHEADVYIEQNFYNSLQKELKKSISIAGVFEGVNFDVDYVISLGGDGTFLKAASKVGPKQIPIIGVNMGRLGFLANVAPEEIKDVLYNVFEGRYEIEERAVIQLEADGKALENCPFALNDIAILKRDNAAMISIKASVNGEFLVTYLADGLVISTPTGSTAYSLSVGGPIIVPQSGILSMTPVAPHSLNIRPIVISDEAEIKLEVKSRSHNFLAAVDGRSEKLSEGVTLTIKKAPHKVRIVKVYGQRFFSTLREKLMWGADTRQF
>NZ_CP054011.1|WP_004358758.1|1847536_1849216_+|ABC-transporter-ATP-binding-protein
MLSKIKKLFQIPETRYTSKEIFRWLWNAWRGNRKQAVLNALIGILSVVVSLATVWAVQHAIDVASHVIEGSIYTAVSIMGALILCDFALSIASVWVKNLLGIKAQNRMQQRMLDRILRSEWHGKERHHSGDVLNRLEFDVANVVSFLTETIPSSVSTLAMFLGAFFYLMSMDWRLAIIIVVMIPLFVLISKVYVRQMRRLTREVRDSDSKVQSVLQETIQHRMLIKTLESDEMIVGKLEGTQHELRRKVVRRTKFSVFSNLVLNFGFAFGYLVAFTWAALRMSAHSLTFGGMTAFLQLVNKIQNPARQLTKLVPAFVSVFTAAERLMELEENPLEEQGEPIEVAGPCGIRLSHVDYRYDDAEREILKDLDFDFYPGSCTAILGETGAGKTTLVRMLLALLKPNKGSVEIYNEKESRELTPLMRTNFVYVPQGNTLLSGTIRENLLLGKVDATEEEMIAVLKKSCADFVFHLPLGLDTLCSEQGGGLSEGQAQRIAIARSLLRDRSIMIFDEATSALDPQTERDLLKNILSNHDKTVIFITHRPAVVDYCDQTLTIEKIQ
>NZ_CP054011.1|WP_004358757.1|1849344_1850274_+|redoxin-domain-containing-protein
MKRILLAVVSVFLMAAPVAFAQTTNVEQTKDLDAKYATNMLKPGTRAPEFKLKTYDAKEIKLSQYRGSYVVLDFWASWCPDCRRDIPAMKALYEQFRDYGVQFVGISFDTDREVWAQTYWGKYQMHWTQVSELKKFRKNTVIDKLYKIDWIPSMYLVDPEGKIVMGTVEIGKLKAKLESLPLTPQVSKTEVLPTFEGGQEAINNYFAQSQRRSIQSFRSKVQAEMTVVFNVEMDGTVTGARVVDVKNVKGTSKHFMKMDAEKQKRVLNNCVEYYKEQAVRLTNNMPKWNPATQNGRPVKSKTTVNIVFQ
>NZ_CP054011.1|WP_036885717.1|1850894_1851392_+|hypothetical-protein
MNKLLWLCGIIAFAVVSCTEGNRGSIKKKDTLSAYDSVLIGRDPGFSCGLTEVYWMLYKNGSVTKCTRSIFASDDGKDTVRTVRFSDDSARRVQELVDDMFVKGTVKDIVAVKGNEHCSDMGGLYIYIYYHGKTVRYEYNWGQTGVKYSSEFNELMNLLKVHDAE
>NZ_CP054011.1|WP_036885716.1|1851699_1853148_+|hypothetical-protein
MRTLLLCVIALCSQVMSMTAQVTGRIEYPHRADYEDQVVLPVDDKGLVIQSFAKDSKECKRYFKTEFYSTAMKLISTDSILIDKGMYFYSDVVESGVLYTVLRQKDGSFMIVAFNPATHKITTTDGEYTRKGSMRNLVIANGSVVFSSTQKKLDRIGIIDLKTGNCRFTDIHFPKVKDKNIFVLENTVIDNTIYALVGVETDVYLLRLDMQGNQLGANNLTADIAERIISASVSKAGNKFFVTGTYSKSKKGGAEGIFFSELKDDRFNNIKFYNFLKLKNFTEYMSDRKQAKIERKKEKAEKAGKEYSLKYLMASHRIMTDGKDYFYLGEAYYPVYYTTWIGNTAVTTFAGYNYTHAVLAKFDAEGNLLWDECFPMEPRIMPMYVKRFVSASLKGKNVNLLFADKNRLVSKLFRNADGNVIQDRTSEIIETDNEDEDVKKMRYSNSQHWYGDNFLVYGTQVVKNSKTGERRKVFAVTKYTIK
>NZ_CP054011.1|WP_004358754.1|1853161_1853689_+|hypothetical-protein
MMRNIDKYRLYQCLLLLGCLLCVPHSVQAQAWDGEGDIKVYAGYANVGGKAGFEIGSDYALSDFISIGGQITYVNVKKHDEGHNNFLLGYDLSLTGNYHWAEVLKLPSVLDIYSGVSVGLRTVGLQAGVRYNFSETFGLYGQVRQNLFKTFGDDVEHGRVYQGKTALSVGLTVTF

Crispr_ID: NZ_CP054011_8

• CRISPR_ID: NZ_CP054011_8
• CRISPR_location: 1915220-1915319
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NZ_CP054011_8

Consensus_repeat	Method
CAGGCAGGTAGCTGCTGCAAGAAGCAGG	CRISPRCasFinder

spacers of NZ_CP054011_8

>8.1|1915248|44|NZ_CP054011|CRISPRCasFinder
AAAAGGCTTGCGATAAGTCTGCTAAGTCTTGCGACAAGGCAAGA

CRISPR arrays and Neighbor proteins around NZ_CP054011_8

CRISPR arrays

The CRISPR arrays of NZ_CP054011_8

>merge|NZ_CP054011|8|1915220-1915319|CRISPRCasFinder
CAGGCAGGTAGCTGCTGCAAGAAGCAGGAAAAGGCTTGCGATAAGTCTGCTAAGTCTTGCGACAAGGCAAGACAGGCTGGTAGCTGCTGCAAGAAGCAGG

>NZ_CP054011|8|8|1915220-1915319|CRISPRCasFinder
CAGGCAGGTAGCTGCTGCAAGAAGCAGG	AAAAGGCTTGCGATAAGTCTGCTAAGTCTTGCGACAAGGCAAGA
CAGGCTGGTAGCTGCTGCAAGAAGCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054011.1|WP_004358689.1|1904256_1905063_-|DUF1911-domain-containing-protein	unknown	unknown	gnl|CDD|370193
NZ_CP054011.1|WP_004358678.1|1916183_1916873_+|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|235376
NZ_CP054011.1|WP_004358693.1|1901633_1902554_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_CP054011.1|WP_004358677.1|1917182_1917773_+|DUF3109-family-protein	unknown	unknown	gnl|CDD|378636
NZ_CP054011.1|WP_004358672.1|1924680_1926045_+|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|236430
NZ_CP054011.1|WP_004358675.1|1918925_1920893_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl|CDD|235542
NZ_CP054011.1|WP_004358685.1|1908190_1909417_-|hypothetical-protein	unknown	unknown	gnl|CDD|373140
NZ_CP054011.1|WP_004358676.1|1917824_1918709_-|AraC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|378964
NZ_CP054011.1|WP_004358680.1|1913491_1914094_+|hypothetical-protein	unknown	unknown	gnl|CDD|173412
NZ_CP054011.1|WP_004358684.1|1909826_1910291_+|energy-transducer-TonB	unknown	unknown	gnl|CDD|273570
NZ_CP054011.1|WP_081445963.1|1926108_1927476_+|protoporphyrinogen-oxidase	unknown	unknown	gnl|CDD|215314
NZ_CP054011.1|WP_004358670.1|1927723_1927978_-|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|376586
NZ_CP054011.1|WP_004358674.1|1921123_1923181_+|TonB-dependent-receptor	unknown	unknown	gnl|CDD|273805
NZ_CP054011.1|WP_004358681.1|1911828_1913346_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|235463
NZ_CP054011.1|WP_004358679.1|1915502_1916168_+|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|235376
NZ_CP054011.1|WP_036885709.1|1902684_1903926_+|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl|CDD|238868
NZ_CP054011.1|WP_004358687.1|1905100_1905823_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP054011.1|WP_036885765.1|1910303_1910786_+|TonB-family-protein	unknown	unknown	gnl|CDD|367555
NZ_CP054011.1|WP_036885707.1|1923292_1924495_+|MFS-transporter	unknown	unknown	gnl|CDD|341038
NZ_CP054011.1|WP_004358682.1|1911072_1911522_+|energy-transducer-TonB	unknown	unknown	gnl|CDD|367555

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_CP054011.1|WP_004358693.1|1901633_1902554_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	3.8e-20	67.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP054011.1|WP_004358689.1|1904256_1905063_-|DUF1911-domain-containing-protein	gnl|CDD|370193	pfam08929, DUF1911, Domain of unknown function (DUF1911). This domain is found in a set of hypothetical bacterial proteins.	9.73663e-30
NZ_CP054011.1|WP_004358678.1|1916183_1916873_+|uracil-DNA-glycosylase	gnl|CDD|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	1.29039e-105
NZ_CP054011.1|WP_004358693.1|1901633_1902554_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.22554e-22
NZ_CP054011.1|WP_004358677.1|1917182_1917773_+|DUF3109-family-protein	gnl|CDD|378636	pfam11307, DUF3109, Protein of unknown function (DUF3109). This bacterial family of proteins has no known function.	2.58452e-104
NZ_CP054011.1|WP_004358672.1|1924680_1926045_+|oxygen-independent-coproporphyrinogen-III-oxidase	gnl|CDD|236430	PRK09249, PRK09249, coproporphyrinogen dehydrogenase.	0
NZ_CP054011.1|WP_004358675.1|1918925_1920893_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl|CDD|235542	PRK05644, gyrB, DNA gyrase subunit B; Validated.	0
NZ_CP054011.1|WP_004358685.1|1908190_1909417_-|hypothetical-protein	gnl|CDD|373140	pfam14575, EphA2_TM, Ephrin type-A receptor 2 transmembrane domain. Epha2_TM represents the left-handed dimer transmembrane domain of of EphA2 receptor. This domain oligomerizes and is important for the active signalling process.	0.00779137
NZ_CP054011.1|WP_004358676.1|1917824_1918709_-|AraC-family-transcriptional-regulator	gnl|CDD|378964	pfam12833, HTH_18, Helix-turn-helix domain.	1.21816e-17
NZ_CP054011.1|WP_004358680.1|1913491_1914094_+|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	0.000749761
NZ_CP054011.1|WP_004358684.1|1909826_1910291_+|energy-transducer-TonB	gnl|CDD|273570	TIGR01352, Protein_TonB, TonB family C-terminal domain. This model represents the C-terminal of TonB and is homologs. TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Most members are designated as TonB or TonB-related proteins, but a few represent the paralogous TolA protein. Several bacteria have up to four TonB paralogs. In nearly every case, a proline-rich repetive region is found N-terminal to this domain; these low-complexity regions are highly divergent and cannot readily be aligned. The region is suggested to help span the periplasm. [Transport and binding proteins, Cations and iron carrying compounds].	9.75126e-07
NZ_CP054011.1|WP_081445963.1|1926108_1927476_+|protoporphyrinogen-oxidase	gnl|CDD|215314	PLN02576, PLN02576, protoporphyrinogen oxidase.	3.92542e-85
NZ_CP054011.1|WP_004358670.1|1927723_1927978_-|30S-ribosomal-protein-S20	gnl|CDD|376586	pfam01649, Ribosomal_S20p, Ribosomal protein S20. Bacterial ribosomal protein S20 interacts with 16S rRNA.	6.41784e-22
NZ_CP054011.1|WP_004358674.1|1921123_1923181_+|TonB-dependent-receptor	gnl|CDD|273805	TIGR01783, Ferrienterobactin_receptor, TonB-dependent siderophore receptor. This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.0429e-47
NZ_CP054011.1|WP_004358681.1|1911828_1913346_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl|CDD|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_CP054011.1|WP_004358679.1|1915502_1916168_+|uracil-DNA-glycosylase	gnl|CDD|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	8.89083e-128
NZ_CP054011.1|WP_036885709.1|1902684_1903926_+|SGNH/GDSL-hydrolase-family-protein	gnl|CDD|238868	cd01830, XynE_like, SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	1.01062e-81
NZ_CP054011.1|WP_036885765.1|1910303_1910786_+|TonB-family-protein	gnl|CDD|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	3.36939e-10
NZ_CP054011.1|WP_036885707.1|1923292_1924495_+|MFS-transporter	gnl|CDD|341038	cd17485, MFS_MFSD3, Major facilitator superfamily domain containing 3 protein. Major facilitator superfamily domain containing 3 protein (MFSD3) is a predicted acetyl-CoA transporter. As an atypical putative membrane-bound solute carrier (SLC), MFSD3 is most likely to be functionally active in the plasma membrane and not in any intracellular organelles. MFSD3 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.85614e-91
NZ_CP054011.1|WP_004358682.1|1911072_1911522_+|energy-transducer-TonB	gnl|CDD|367555	pfam03544, TonB_C, Gram-negative bacterial TonB protein C-terminal. The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.	0.00175587

Protein sequences

>NZ_CP054011.1|WP_004358680.1|1913491_1914094_+|hypothetical-protein
MKNRKLVLSLVALAGLSSLSAQAQTNNTEKPHETIMQRVDTLAKKVGADVKHAEGVEKAKLNADAQKVGAAVKKAETTEKAKLNADKQRVKADLAKDKEKVNKVYQDDKAKFNADVKKAENGLAKDEQKVKNTYRKDEAKVKQGFAKDKQKVRNAYRKDKAKVKAGVKKVKQGLAKDGQKIKNTYNKDKAKVKAFFKKEK
>NZ_CP054011.1|WP_004358681.1|1911828_1913346_+|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MAKKALLMILDGWGNGKHGKGDVIYNTPTPYLDYLNAVSAHSELQASGEDVGLPDGQMGNSEVGHLNIGAGRIVYQDLVKINKACQSGDILKNQGIIDAYSYAQKNGKKLHLMGLTSTGGVHSSLDHLFKFIEIGKEYNLKDVYVHCFMDGRDTDPKSGAGFVAEIQKVCDANDAHIASVVGRFYAMDRDKRWNRVKEAYDLLVEGKGVQATDMVKAIEASYAEGVTDEFIKPITNSSVNGKIEEGDVVIFINFRNDRAKELTSVLTQQDLPEEGMHTIKDLQFYCMTPYDANFKNVNILFSKENVMDTLGEYLSKLGKKQLHTAETEKYAHVTFFFNGGREQPYEGEDRILVPSPKVATYDLQPEMSAFEVKDKLVGAINTQEYDFIVVNFANGDMVGHTGVYNAIAKAVWAVDQCVKEVVEAAKANDYETIIIADHGNADNAINEDGTPNTAHSLNPVPFIYVTNNNSATVKNGRLADVAPSILHIMGLEQPADMTGENLITD
>NZ_CP054011.1|WP_004358682.1|1911072_1911522_+|energy-transducer-TonB
MKKFLFIFFLSLMAVGSIHATNSSQMKFQQENMSNMKAITLPENSKKARQDTVSVLKEFPFFPGDFNEFIFSNFHYPPSLQENCIQGREVVKFCVNPKGKCDHFSIVRSVDPLIEKEVLRVLKLMPRWIWRDSSKKCLWMVKAVEFQLR
>NZ_CP054011.1|WP_036885765.1|1910303_1910786_+|TonB-family-protein
MIKKLFLVLFLSFVVVGNIDAQKQKRTMKPKKKEQIEQPYCAEPAFEPCNDTLNVDTLGAKMFETVEGLKPSFPGDILEFIAVHLQYPPELAENSVSGRVIIKFFVTPSGCCCLFRVMRSVDPYLDREALRVLKLMPAWKWERRPKQGVWQLVPVTFRLL
>NZ_CP054011.1|WP_004358684.1|1909826_1910291_+|energy-transducer-TonB
MMKRILLAMSLSICMAATVNAQQEKMSMKSYENEVRKDTIDTLEVKNERHKIFDCWFPPMPSFPGNIQQFLRAHLVWPAGRKNKKVEGKVIVKFYIERDGTCSQFKILRSLSPAFDTEALRVLKLMPKWNVDSTAKGGTWYVLPVSFKKQNVQQ
>NZ_CP054011.1|WP_004358685.1|1908190_1909417_-|hypothetical-protein
MCIFANMKKRPILLLITLLTLLSCSQRKLPNYPATDEGITRMRLDSAAFFMAKHDTRNAMYQLKSAEKHLFNVTEDSLKFATYYRIALLNAQNGAYKLALDYFAHTARYANDSKKSHRLTDIYLGKASVFNQIGQRDSALLYVKKAEAFKPRIRKDQEQSINQLRTRIEKRQILSVSPEKDIEIVQIQDRYEVAIAQRKALQLQLYIAYLVIILILLTSGIVVWFRRRMRQQLHTYRRQQEMTEQNIQQLLRRKDATIDEMKAEVDSKINELEQLKQKTPTHNGDTKTADSIEQTKLGIDALYTILKGGNISQMGKREQQALNAIMPNFDYDLAYILNNPRYAFTPKETFYYIMEHNGMTDEQKADAFCCTSQAIRSIKSRMKKKMEKSQEELPEADLELEEEDNTAQ
>NZ_CP054011.1|WP_004358687.1|1905100_1905823_-|hypothetical-protein
MMSKLSVILWLLLFATTCVGQDNLSNNSDKDTLRYKRFDIEEYKRLVRKNPTAYRIRKEGKLGELIELSDEYVNNSFAGFRESHTYRDSPYEYIYLYNTVGNITAYCAYLYQMPVGKGYQFDGHGHEVKCVDYDLPYKFSIDSLKVKMLHQYGINLMDKKEVFSVRRYEEREYIKRPIYIVCAHWKDNRNDIYLIDGINGETLYTQKAVEIIRDDSPTDWKSIEELYHDSKSYSSIPMQQ
>NZ_CP054011.1|WP_004358689.1|1904256_1905063_-|DUF1911-domain-containing-protein
MGIFDYFLSHAKQKQDKAIRDKIKNRKFFSKMLIEIAKNKGETERLILEANTNKRLDTVYLHWSLGERYISGIEIRYSMDANMTELKRIYSNSLEYFITGLAIEDPIYFEILKRVSLGILLNVSCAEFQQLIDYVERVDNQAKPADWTPDLLLWFMLNSRMGEDKKQTHANKLAFPKLYKGLFKLTQLSDAQAAKKALIDYIRKWYNLNKDAPWYNNHLKTSCYRGYWAWEVAAVAKILQIDDSDLKDNPYYPYDMVHWEEDDTTNDE
>NZ_CP054011.1|WP_036885709.1|1902684_1903926_+|SGNH/GDSL-hydrolase-family-protein
MFTRKILFVLLFFITFNAYAQQERWVGTWACAPQTVDKGFMPYNNQMTNRSVRQVVKVSIGGPVIRLQLSNELSSEPVEITSVYIAKAGEGSEIQKNSAKYLRFNNKRRVTIPAGKAAFSDALKFDLQPLERLSITINYLKAPKEPTVHMGSRTTSYILRGVTNANTDFSTAFKEDHWFNISAIDVLDASASSVAILGNSITDGKGCVTNAQDRWPDFMSAVLNGEHESKSPKTGVLNLGIGDNRILSVGLGQPGKERFDRDILGQRGLRAVIIFEAINDIGTSTNPEETARQLIEAYQVMIEKARQRGLKVYMGTITPFNGCKGYFTEARDAARKTVNEWIRTNHEIDGFIDFDELMRDPSSPDRLRKEWQIGDWLHPNPKGYKMMGEYAAKSLEEMNVSTPSNQRPLTERK
>NZ_CP054011.1|WP_004358693.1|1901633_1902554_+|WYL-domain-containing-protein
MRFDKLKKQLELLILLSDGRNYTVEELCERMNLSRRNFYYLLDFIKHAGFIVFKNQGYYHIDRRSPFFTQLLQTIQFTDKDVKTIHSVLTMAGNDSEMVNQLRQKLESSYNFSVSAESPIRRQMESNLKLLRKAMVEKKTVRLIGYSSPHSHSVKDRLVEPFLLLHNNEDVRCHELVSKQNKTFKISRMTSVEILDTSWLHEDKHRQVFTDIFMFSSEERYRVKLRLGQLSHNLFKEEYPQGAHYITPNADGSWLLDIEVCDYRGLGRFVLGLFKDIEIIEGDGFKAYLRAEIESLIDSSNQLLQK
>NZ_CP054011.1|WP_004358679.1|1915502_1916168_+|uracil-DNA-glycosylase
MGVKIEPSWEQQLRGEFEKPYFLQLVEQVRQEYAQQPCYLPGKLIFNAFNLCPFDKVRVVIIGQDPYHEPGQAMGLSFSVPEGVQLPPSLQNIYKEIAADLGTPIHQSGDLTRWAEQGVLLLNATLTVRAHVANSHQRLGWGTFTDAAIKALSDGRENLVFMLWGVFACSKKALIDQQRHCVIESVHPSQRFANRGGWFGQHQFSRCNAYLTACGAQPIEW
>NZ_CP054011.1|WP_004358678.1|1916183_1916873_+|uracil-DNA-glycosylase
MEWILEESWREKLKDEMGKPYYRELVDKVQEEYENETCYPPEDKIFNALNLCPFDKVKVVIMGQDPYFNPGQAMGLSFSVPEGTQLPPSLQTLYRALKISLDASDKPSGNLTRWVEQGVLLLNTTLTVRKDNPNSHRKYKWWRFTDAVIKALDAEREHIVFMLWGRIAQRKERLVHVDNDRHMVLKAIHPSPLAVRRKGEWDGKEHFMCCNKYLNEYGIAPIEWTVVSE
>NZ_CP054011.1|WP_004358677.1|1917182_1917773_+|DUF3109-family-protein
MGNTYDHIFMVGDVLVSPDIINVKFCCDLDKCHGQCCIEGDAGAPVTLDETMEIENVLDTVWGDLSASGQAVIDKQGVAYTDEEGDLVTSIVGGKDCVFTCYENGCCLCALERSYRNGKTGFVKPISCSLYPVRVKDFGNGTCGINYHHWRICADARKKGEELNLPLYKFLKEPLTRRFGKEWYDELCEVAEQLLG
>NZ_CP054011.1|WP_004358676.1|1917824_1918709_-|AraC-family-transcriptional-regulator
MNKKIRLIEVNVAQARAVYPEGKFIDNDLILFEDITQVPLPTNPSRMKSLFLALCTSGHAQYTVDTKMHEVGAGDVIIISEEQVVADYMLSRDCKGIALILSYDFFQNIVSGVHELSALFLFARTHPVFHLDNNQAKALENDIQHIKEKIIDTGHRFRRELVMTMLKALIIDMSDIIYRFQQVGEAGQTRAEAIFRDFIQTVEKNYRTERRVSWYAQQLCITSKYLSETVRTVSRRTPSDWIDSYVTRELRVMLRNSTMSIKQIADELNFANQSFMGKYFKEHVGMSPSKFRKS
>NZ_CP054011.1|WP_004358675.1|1918925_1920893_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MAENPENENNYSASNIQVLEGLEAVRKRPAMYIGDISEKGLHHLINETVDNSIDEAMAGYCQNIEVTINEDNSITVEDDGRGIPVDMHEKLHKSALEVVMTVLHAGGKFDKGSYKVSGGLHGVGVSCVNALSTHMKSQVFRDGKIYQQEYEKGKPLYPVKVVGETDKTGTRQQFWPDPEIFTTTVYQWAIVARRMRELAYLNAGIKITLSDLRPDPETGKTRTEVFHAKDGLKEFVRYVDRHRQHLFDDVIYLKTEKQNIPIEVAVMYNTDYTENIHSYVNNINTIEGGTHLQGFRAALTRTLKTYADNDPQISKQLEKAKIEIAGEDFREGLTAVISIKVAEPQFEGQTKTKLGNSEVSGAVQQAVGEALTDYLEEHPNEAKMICNKVILAATARVAARKARESVQRKNVMSGGGLPGKLADCSNKDPKDCEIFLVEGDSAGGSAKQGRDRYTQAILPLRGKILNVEKVQRHRVFEAESVMNIIQSIGVRFGVEGEGDFEANTDKLRYDKIIIMTDADVDGSHIDTLIMTLFYRYMPKVIEQGHLYIATPPLYKCTYKKVSEYCYTEQQRQAFIDKYANGDEEDKAIHTQRYKGLGEMNPEQLWETTMDPKTRLLKQVTIENDVDDIFSMLMGDDVEPRREFIEKNATYANIDA
>NZ_CP054011.1|WP_004358674.1|1921123_1923181_+|TonB-dependent-receptor
MLNTLLFASLAISGVAGVTPDSVVNKDASLNEVVVTDFKQNKRNLTSIAVSTINSQQLLNQQIVNLKELTAVMPNFYMPDYGSYANTPIFIRGIGAKMKGSAVGFYVDGVPHFESSAFNIDLSDIAAVDVFRGPQGTLYGRNTIAGVINVYTHNPLDYQKTRIKVGYGKYNDVVAQASNYSKLTDKLGLSSAISYHHNDGMFTNQFQNDKADKVNEVEGRLGLYWRPTMNWLIHLNSTLTHSKQNGYPYAPYDLTKDVLSPISYNRNSTYKRLISTTGLNARYENSRISFNSQTSYQFIKSHQGIDQDFTPKDLFYADNSYHQNMLSQELTLKSNDKGRYQWIIGMFGMLLHSAPFIETSYYTKDFSTPTSYKNPTAGYAIYHQSSYNIWRGLSATVGLRFDYEHAKIDYNQDKVTLTTGANAHVKDFVSSANFRQFTPKFTLQYLTNRDNLYYASVARGYKPGGFNTIFKTDAERAYDPEYSWNYEVGARLKFLNGRLTAEADLFYIDWRHMQTTYTVPAVGNLIANAGHTDSKGFELSFAYHPIKSLQFSMNYGYTHARYLEYKKSATEDFSGNRLPMVPNHTLSIDGTYTVLQAGWFNKIVVNAGFTGLGRIYWADDNVVRQNFYGTLNAKVSLTKGIFTWDLWGKNLTGTDYIAYSFKMSTGNYAQKGKPLTFGTSLSVSF
>NZ_CP054011.1|WP_036885707.1|1923292_1924495_+|MFS-transporter
MFNSISSKKLSFGTFFCLYIAQMVPSSFLMTALQVIMREGQYSLATIGLLNLVRVPWTIKFLWSPFVDRHCVTVRDYKRTIIATELIYAVALLATGLINVRSEIMLVVILAFISMLASATQDIATDALAILSFKKHDHSMLNSMQSMGAFGGAVIGGGVLLILLKSYGWNVVVPCLALFVCMMIIPLMFNPHIKIENEKPRERAKWTDIFSFFGRKEIWRQIGFLLLYYMGIIGILSMMRPYLVDKGYDMKEIGFLTGIVGTAASFVMAWFSGVLIRRIGIYKARIIIAGLIILAPIYFLAMTFADFNKTAFVIGIIYIQACYGLATVVLYTTAMRCVRPGREGTDFTIQIVISHVSGLLVAVLAGTVAHIFDYRGLYIAETVVAIFSLIYVLSAFKKEQ
>NZ_CP054011.1|WP_004358672.1|1924680_1926045_+|oxygen-independent-coproporphyrinogen-III-oxidase
MKQELIDKYNVSVPRYTSYPPANFFRLFTGEEFLREVDYSNEVREKNLSFYFHMPFCRRLCHYCGCNSYPMAKQEHVEAYVQALHKEIDLVAKHLDNSRRISQIHYGGGSPTAMPVSVLKELNEHLLSLFSTIEQPEIAIECHPGYLTAEDWQGLLDARFNRFSLGVQDFNEEVLRLVNRTPSELPTEEIVAILRNAGVNINMDFLFGLPLQTSDSFKKTIERAVAMRPDRVTTFSYGHCPWIFKRQMILEKAGLPDTEEKALMFQKAKDVLHEAGYLSVGLDHFVLPNDELSEALQSHRLHRNFQGYCTRRTTGQVYAFGVTGISQLETAYAQNTKSIDEYITEVSAGTLPIRKGYQLTSKERIVREVIERLMCNYHLDWTHLAEDLVVSVAEVKEAINYDVERLQEMERDGILCLTENTLEMTGEGNPFVRTVAAALDSMMVATDKKFSKPI
>NZ_CP054011.1|WP_081445963.1|1926108_1927476_+|protoporphyrinogen-oxidase
MMEERKIVVVGAGLTGLTCAAYLRRKGQDVVVLEAADRIGGLMQTEEVDGFVMEQGPSTGTIKYPEVAELFDMLGDDCTLEVAQSSAKCRLIWKDGRFHALPSGLWSAITTPLFTLKDKFRILGEPWRKKGIDPNESVGSLAERRLGRSFVDYAVDPFLSGVYAGDPYQLPTRLALPKLYDLEQRYGSFIKGAMALAKQPKTDREKRATKAVFSTRGGFRSLVSALGRVIGDERIRTNCKELSIEPLGDKWKLSWGENTIIAEQVITTCPAYALPKLLNFLPKEQLDDLSNLYYAPVIEIGVGMKNTGDVHWNAFGGLVPSKEKQNVLGVLMPSACFQGRSPKEGANYACFIGGACHPEYINKTDEELIGLVNTSLHTMLGYPKGTCADVIRIYRHSHAIPQYMPETDARLRTIDAVELAYPGLHIIGNLKDGIGMGDRIKQAVDMAEKISLSVS
>NZ_CP054011.1|WP_004358670.1|1927723_1927978_-|30S-ribosomal-protein-S20
MANHKSSLKRIRQDKVKTLHNRYYAKTMRNAVRKLRSMTDKEEAVKLYPVVQKMLDKLAKTNVIHQNKAANLKSALCKHVAALG

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	371322 : 417444	34	Acanthamoeba_polyphaga_lentillevirus(33.33%)	tRNA,transposase	NA
DBSCAN-SWA_2	514250 : 572912	38	Flavobacterium_phage(50.0%)	transposase	NA
DBSCAN-SWA_3	894240 : 901584	8	Paramecium_bursaria_Chlorella_virus(33.33%)	NA	NA
DBSCAN-SWA_4	1556805 : 1618228	44	unidentified_phage(33.33%)	tRNA,integrase,transposase	attL 1563089:1563103|attR 1603635:1603649

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP054011|371322:417444|DBSCAN-SWA
ATTAATCGTTGAGAATCAACAATGAGTCGCCGAAGCAACCAAACATATAACCATTCTTTACCGCTTTGTCATATGCTTCCATCACAAGATCATAACCTCCGAAGGCTGCTGTTTCCATCAATAAGGTTGAATATGGATGATAGAAGTTGACCAACATAGAGTCAGCAAAGCCAAAGTTGTATGGAGGGAAGATAAATTCATTAGTCCAACCATCGTACTCTTTCAACATACCATCTGTACCAACGGCTGTCTCTGTAGCCTTAACAACACTCGCACCGACGGCACAAAGGCGATGTCCTGCTTGTTTAGCACCATTGGCAATACGACAAGCATCGGCATTGATGTGCATCTCTTCAGAGTCCATCTTGTGCTTTGTAAGATCTTCTACTTCAATGTCATGGAAGTTACCTAAGCCACAATGTAAAGTGATGAATGCTTTCTTGATTCCCTTAATATCCATCATCTTCATCATGTGTTCAGAGAAGTGGATGTTTGTTCCTGGTGCAGAGACTGCGCCTTCGTTCTTTGCAAAGACTGACTGGAAGTGCTCCATGTCGTCAGCTGTTGCGTGTGCAAACTCTTCACCTTCCTCTTTTGGGCGGTTATCAATGATATAACGTGGTAATGGAGCTTCACCCAAAGTAAACAACTCACGCTTAAATTCATCGTGAGGACAGTCGTAAAGGAAACGAAGTGTGCGACCACGAGAAGTCGTGTTGTCAATAACCTCAGCCACCATCGTACCAGATTCATCAAAGAAAAGCTTGTTACCGATACGAATCTTACGTGCAGGCTCAACCAATACGTCCCAAAGACGCATCTCCTGATTCAACTCACGAAGGAGGAATACCTCAATCTTAGCATCAGTCTTCTCCTTTGTTCCATACAGACGAGCTGGGAAAACCTTAGTATCATTGAAGATAAAAGCATCGCCCTCATCGAAGTAATTGAACACATCTTTGAAGCGGATGTAGTCTTCTTCCTTAGGTTCACCATTGATCTCACCCTTAAACATGTCAATCTTTCCTGACTTACGGTGTAGCACCATCAGTCTACCTTCGTCACGACGTGTAACAGTAAAGGTCTGTGTACTGCCGTCAGTACGAGTCAGTACACGTTCAGATGAATGTGGATATAAGGCTACCTGCTCTTTTGGTAGGTTGAATTTAAACTGTGAAAGCTTCATATTTTTATATTGAGGAGTTTATTATTTTTCTATTGTTTGTTGCTGAAGCCATGCTTCAAACTGGTCATAATTGACGCAGTCTTCCACTCTTACGTCTCCAACACGTGTGCGGCGCAATGCTGTAAGATAGGCTCCGCTATTCACTGCTCGTCCAAGGTCGCGTGCCAATGCGCGGATATAAGTACCTTTACCGCAGACGACACGAATTGATAGTTGCATCTTCTCTGTATCGAAGTCTAATACTTCTATCTCATCAATGCGAATGTTCTTAGGTTTTAACGTGACATCCTTACCTTTTCTACGATAGTCGAAAGCACGCTTACCATCCACCTTTACAGCACTGTAAGTTGGTGGAATCTGCTCGATATCACCCACAAACTGAGGAAGTGTAGCGTTTATTAGTTCCCTTGTTATGTGTTCTGTTGGGAAGGTTTCATTCACCTCATGCTCCATATCGTAGCTCGGTGTGGTTGCTCCCAACTGAAGAGTAGCTGTATATTCCTTTGTGTGTGTCTGCAAGGTTTCAATCTGTTTTGTCATCTTACCCGTAGCAAGGATGAGTACTCCTGTAGCCAAAGGGTCTAAAGTACCTGCATGACCAATCTTTACTTTTCCGTCATTCGCCTGTGTACAAAGGTAACGTACGTGCGCCAATGCTTTGAAACTGGTGATTCCGTAGGGCTTGTCAATAGGGATGATTACTCCTTCTTTGAAGTTCATTAGGGCAATAAGTATATAAGATTAGTCAACCATATTCAGTGGAATATCACAGAGCAGCATTATAATAATGATAACGCCAACGATGATACGATACCAACCGAACCACTTGAAACCATATTTTGCAAGGAAACTTACAAACCATTTCATTGCCAATAGCGCAACGATAAATGATACAACACAGCCTACTGCGAGCATTATAAGGTTGTGAGCAGACGCCCATGTACTGTCACCTTTTAATAAATCAAGTAGGTCGAGCAGTGTTGCACCAGCCATAGTAGGTACTGCAAGGAAGAATGAGAACTCTGCTGCACGCTTACGTGTCAATCCGTTTGCCATACCGCCAACGATGGTAGCCATAGAGCGGCTTGTACCAGGGATAACCGATAAGCACTGGAAAAGACCAATGCTAAAGGCACGCTTTTCTGTTACTTGATTCTCTTCTTTTCCCTTATTGAACAATTTATCACAATAAAGCATGAAGATGCCACCCACAACGAGCATTATTGCTACAACCCAAACTGAGTCGAGCAGCCAGTCAAGTAAACCACTTTTCTTAGCTGCTAAGCCAATGATAACAGCTGGTAGGACACCAATGAACAATAACCAGTAGAAGCGGATTGGATGAATAATCTTCTTGAAAGTACAAGTTTCATCAACAGGTACAGGTGTATGGTCGATCTGGAAAAAGCGTTTCCAATATAAGCATACGACAGAGAGGATAGCACCAAACTGGATGATGAAGGTAAAGGCATGTACAAACTCGTCACCTGATGGTACACCTAAAAGATTTTGTGTGATAATCATGTGACCCGTAGATGACACAGGAAGAAACTCTGTCATTCCTTCGACAATGGAGATAATAATCGTTTGTAAAAGTGTCATTATTCCTCCACTTCTTTAGTTTCTTTCGGCTGATAGAGAATAGCACCAATGATAGAGATAAAACCAATAAAGGTAACAATAGGCGCTACCTTGATGTGACGGGCACTGAAGATGTCTGGATCAAATACGGTTTCAGTAGATGTTCCACCACTCATAAGGATAAAGCCGAGAATAACAACGGCTACACCTATAGCCAACAAAATAAAGTTGGTCTTACCAAAAGCTAAATTTCTTTTGTCCATATTCTATTTTTGAAGAGTCCAAGGGGCTGAGATTGAGAAGTTAAAAAGATTAATTGGAATAATGAGGTATTCTCTTTTCCGTTTATAAGAAACTTTTACTCTCTTATCTTTTCCCCTTTTTACTGTTCCTTTTAAATCTTATATAAGTCACCTGCCTTCATACGCAGGAACTTGTTTACTGACAGCCATGCGCAGAAAGTTGCGATAATCACACCAAAAGCTAACATTACGATTGCTGTGATAATCAATGCATCCCATGACAATAATTTCGTAATCTCTGGTTCCTTTTCGTACAGGAGGCATATTCCGATACCCAAGACTGCAATAGCCAATAGGGCTGAAACTAATCCTTCTAATACTGCACGGCGCAAGAATGGCGCACGGATAAAACTCCATGAACCACCAACAAGTTTCATCGTGTGGATTGAGAAACGATGTGCATAGATACTCAATCGGATAGTATTGTTAATCAGAGAGAATGATATGATGGTGAGCAATACAGCAATAACCAATAACACCAAACTAATCTTACCCAATGTTTGGTTTACACTTTCTACCAAACTCTGTGGATAAGTGATGTCACTCACACCACGATAGGTACGCAATTGCTGAACAATATTGCGGATAGAGTCATTGTTAGCATAGTTAGCCTTCAACTGTACTTCTACCTCACCCGTAAACGGATTTTCACCTGCAAATTCGGCAGGGTTGGCACCTAATTCTTTGGTTCCATCCTTCAACGCCTGTTCTTTACTGATAAAGTTCAAGCTATTGATATAATGCAAGGTGCGAATACGCTCGCAGAGAGCAGTACTCTCTTCCGTATTCATATCGGGTTGGAGAATCATTGTGATAGTCAGATTCTCCTTTACATAAGAACTAAGATTGCGACTGGTAAAGCCTGTGAGTACAACTATACCAATCAGCATCAGTACCATAGCTGTACTGATACATAGTGTGACAACCTGCAGACTATGACGACTGCGGGCTTTGTTTCTTTTTTTTGCCATTTCTTTAATAAGGTATAATACACCAAAGTTGTTGCAAAGATACTGCAAAATAAGGTAACGACAAAGGAAATTATGCTTTATTTAGAGATAAAAGATGAAACTTGTGAGCATATTACTATGGAAGGGAAGGTAGGGGAGTTATGCTCGAAAGTTTAACCCAAATCGGTCATTAGACCACAAAATGTACATTCTTACGATAGTATGGTGTTGTTTCCTAACATTTTTTCTTTTCTTATCGGCATCTTGTTAGTCTTTGTAACTTGACGTAGCCCGCTACGCCTGCGTTCCAAAGGCAAACAATCTGCTCGATAATAAAACAAAATATGTTTAGGCTCTAATGACCGAATTGGGTTTAAAACAATTACGTTGTGTTTTTCCTTCAACCGCTATAGGGTTATTTAATGTCTCCTTTTTAAGCTTATAAGTGGGCATTGTCTCAAGGTGATAATTTTCTATTTTGTAATAAAAAACTTCTGTGTGGTGATGTTAGGACTAACAAATGTTAATATCTTATATTATAGTTTCTCCACTTTATATCAGATGTGTAATTTGCGGTACAATCATATAAGGGGGTATGTGACTTCTTTCCATAACAGTACCCTTTGTTAGGAGAGTACGACAACCACAAGTCTTACATTGAAATGCTTTTCTACCATCTAACCATTTGTGCTCAATATAGCCACATTTAGGACAGGTAATTCCTACATCTTCCCGAATCTGACGAAAATAGTCTATACAGCTTTCTTCGTCAGGAAATATTTGAAAGAAATCTTTAAGTAACATTAAGTTCATCATTTCTTGCAAAAGAAATTGAATTACAGATGTTTATAAAGAAAGATTGTTTAAATTAACATTCTTTAGTCCTAACATCACCACACAGAATAAAAAACTCACACTCGAAAATGAATAGATGCTCTTTAAGGCTCTTAAAGACGCCCAATTAGCTTCTAAAAGGTGCCCTTTTGAGGTCTTATTAACGCCCTTTTGAAGTCCAATTAAGCACCTTTTGCGCTGCTGTTTTGTAACTGTCTGATCTGTATTAAGTTACAAGAGTGTTCGCAAAGGCTGTTTTTTTGTCTTTTTAGACGAATGTTTTAAGAAATAATGTAAATAATTTTCGCGACTCTTGTTGTGGTGATAATACTGTTGTATGTCTTCATAAAATATTCACAAATCGTATGTGCTTTGCAATAAAATCATGCAAAATACGTTTAACATATATAATCTTTAACAAAATAAATAACAAAACCTATGAAACGAATAGCTATTCTAATCGTATTAGTTACATCAACTTTGGTATCAATGGCACAGAATAAATTAGGTACATGGTCAGTGATACCGCATGTAGGAGTGTCTATATCTTCTTTGTTAGGTGGGTCTGGAATCTATGAAATTGGTATTGAGCAAGGTATAGAAGTAAAGACACATGCATTGTTAGGGTTTGTTGGAGGGGCTGATGTGATGTATCAGGCTTCTGATGCTGTAGGTCTTTCCGCTGGCTTATCATTTGTTCAAGCAGGCTGTAAGTTGGAGGATTATACTGATGACCACACTGTAGTTTATGATCGTTACTTGCGAATAAATTATGTGAGTATGCCAATTTTAGTTCATAATAAGTTGTTGGCAGGTTTTTCTGTTAAGGTTGGTATAGAACCAACCTGCGTCTTTAATGCTAATAATCATGAAGTATATCAGTCGTATTCTGTAGATAAAGACGGTAAGAAGACTAATTTCCAAGAGAATACATATGATTTTGATATAAAGAATGGTATGTGTAAGTTTGGTCTTTCTATACCAATTGGTGTAAGCTATGAGTATGAAAACGTTGTGTTAGGAGCATTATATCATGTGGGAGTCTTTAAGATTTACAAGGAAGGCGATTCTTCTCGTAGCAGCGTGTTTGAGGTGTCTGTAGGTTATAAATTAAATCTTTAAGACAACGCTAAGACTTTTCTTGTTTATTAAAGAAATGCGATAACCATTTAATATCGTTGTTCGTTGTCTTTCATTTCAGGAAGAAGTGGAAGACAACTAATTAGGGTCTTCAGGATTTTGGAGTGATAAGGTTTGCCACTTATGTTTAGAGTTTGAAGTAATGTCACACGGAGGAACGGAGAGAACGGAGGATTATTAAATACAAAGCTATAGTAGTAACGGAGGCACCGTCGGTGCATAGAGCAACGGAGCTTGTTTGCCAATTCTATTAGCAATTTATATACAAAACGTTTATTCCAAAATATTTAGCAAGAATCTGTACGCTACACCTCCGTCACTCTTTGTGCCCTCGGCACCTCCGTGACATTGCGTTACCTCCGTCCCCTCCGTGACTCTGTGTGCCTTATATGTAAGAGTTTAGTTTATCACTCCATATTTCGGATAAGTCACTAATTATATGAGTAAATTGCTTATAGTGGTTAAGATTTTCAGTAAATAGGGCTGTAAATTAAAAAAAATACCGTAAGTTTGCACATTATAATAAATATGATGAAACGGAACTTTTTAATCACATTATTTCTAATAGTGAGCTTGGGTACTATTGCTCAAGTGAATCATCCTATCTCTGTTCGTAGCGATGAACGGCCGTCAATGGATAAGATTCAAGCGTATATTGATTCACTAAAATCCCTGAAAGATAGTGTGTTTACACGTAAGATGCCGAAAGTTCAACGCGGGCAGAGGCTTCGTCGGAATGATATGCGATTGTTTTTACCACTGACCTATTATGGTAATGTGGCAGAAAGACTGTTTACACGTGATAGAAAGGAAAGTCCAATTCTCTCAGAGTTGATGCACCTTTACTTGACACGTCCAGACCTTGTGGAGGGTACTGATCGTATGGTACAGCAACAGCAGACGAAATTAGATGATATTAAAGCACCAATACATCATGATCCTACATTGGTAGAAAAAGTGGCTGATCGTCCTGTTGAGCCAACAAATGTACCTGTAGATGTTTTGGTAAAGCGTCCTAATTTCTGGACGTTTAGTGGTGATTATGCTCTACAGTTCCTGCAGAATTATGTCTCTGGAAACTGGTATAAAGGTGGCGAAAGCAATTATTCTACTTTGGCTTCATTGGTCATGCAAGCTAATTATAATAATAAGCAGAAAGTGAAGTGGGAGAACCGTTTGGAGTTAAAATATGGTATGCAGAGTAGCCGCTCCGACTCCCTACACAGTTTTAAGAGTACAGAGGACCTGATTCGTCTTACCTCTAAACTCGGTTTGCAGGCAACAAAGCGTTGGTATTATACGGTTCAGTTTATTGGCAATACGCAATTTAGCCATTCTTACCGTTCAAATGATCCAAAGATTTATTCAGCTTTTGCAGCTCCGTTGAACATAAACCTTTCTATCGGTATGGATTACTCGGTAGACTGGATGAACCATCGTTTGAAGGGTAACTTCCACTTGGCACCATTAGCTTATAATATGAAGTATACTCGTATGTTAGAGTTGACGCGTCGTTTGGGTATCAAGGATGGTAATCATTTCCTGCATGACTTCGGTTCTGAGTTTACGGTTGATTTAGAATGGCAGTTGATGGAATCGCTTACTTGGAAGACACGCCTGTATGGCTATTCGACTTATAAGCGTACGGAGTTAGAATGGGAGAATACCTTTACCTTCCACTTCAATCGCTATATATCAAGTCGTGTGTTTATCTATCCTCGTTTTGATGATGGTGTACGTCGTGATGACCATTATGCTTTTTGGCAGTTGAAGGAGTTTGCTTCTATAGGCTTCCAGTATAGTTTCTAATTGAATGATGCAAGTTAAAAGGTATAGAGGCAGTTTCGTGGGTTCTATCATCAATATAACCTTAAACGTAGAGGAAGATGAAAGTAGCGGAGTATCTAAAACTTGAAACGTAAATACTAACCATCCCCTTCTCGTACAGAGAGGGGATAGTGTGTGTTATTATAACTGCATTTCTTTTACTTTTTTTATAATCAATAGACTTTGTGATTCAAGATTTTTATGTACATTTGCATCGTAATCAATATTAATACCGTTTTTATGTAGATTTTATTGAGCGCACATTTGTGAAGGAATCTAATTCTTTTAATAAGTTAATATCAAAAATAATAACAATAAAGACTAATCAATGAAGTATCATCAACGCATGTTTAGAACTTTAAGAAGGTTACCTTCTTTGGTGTTTCTGACAACTTTTATCTTGATGCTTTCGTGGAGTTCTCCTGCTTCTGCACAAGTAGCGGGTAAGAAATTCTCGATTTCGTTTAAGGATAAGAGTGTTGCTCAGATTTTGGATTTCATTTCTACAAAGGGAGACTACAAGATTAATTACTCTGACGATGTTAAGAACGACACGTTGCTTCTTACGATATCGTTTGAGGATGTAGACGAACTGAGTGCTGTGGAAAATCTATTGTCTCACTCATCTTTCGTCTATAATATCGATGGCAAGGTGATTGATGTGTTCAAGATGAAGAACGCAACACAAGGACAATACACTATTCGTGGCACAGTAAAAGACAAAGACGGATTGGGAGTGCCTTTTGCTATTGTGCAAATTAAGGGTACGTCGCAAGGTGTTACCGCTGATATTGACGGTAACTTCTCAATGCCTGTAGAGAAAGAGGAGGGGACGATTACTATCTCCAGCGTGGGCTATGATGCTAAAACGCTAAAGTATCATGCTGGTAAAGCTATGAACGTTATCCTGACTTCTTCAGCTATCGCAATGGGTGAGGTTACAGTTGTTGCCTATGGTAAGCGTAACACACGTGAGCAAGTGGGTGCTGTGGCTTCTGTAAAAGTTGAGGATTTGCAGAAGGCACCAACGGCAAGTATTGAGAATCTCTTGCAGGGTCGTATGGCTGGTGTAGATGTAACTAACCTCTCAGGTTCACCTGGTGGTGGTGGTTCTCGTATTACTATTCGTGGTTTCAGCTCTCTTAATCAGAAGGGTATCAATGATGGATCCCCTCTCTATGTAATTGATGGTATTCCTGTGTCAAGTAGTGCAGGTGATGCAACGGGTGGTATCAACCCATTGTCAGGACTCGATCCTTCAAGTATTGAGTCTGTGCAGGTACTTAAGGATGCTGCATCAGCTTCCCTCTATGGTTCACGTGCTGGTAATGGTGTTATCCTTATTACAACGAAGAAGGGTAAGTCTGGACGTTCTGAAGTGAGTTTTAATTTCTCACAGTCTCTTTCTTGGTTGCCAAGTACACCAATGCAGACCCTTGGTAAGGGTGAACGCGATATTGCTCTCCGTCTTGCTAAGAGCCAAAGAGGTGCACATTATGACTACATGACAGATAAGTTGATTTATCCGGGTTCTTATAAGGATTCATACGGATGGGATGCTGATAATGATGGTGCATACGACTATCTGTGGCGTAATGGTAAGGTGTTGGATTCAGAACGTCGTCTGCCAGGTATTGCGCAAGATTCACTTAATACTTTCTATAACAACAGAACAAACTGGTGGAAGTATGCCTTCCGTGTTGGTAAGGTGACTAAGGCTGATATGTTGTTAGCAGGTGGTACGGATAATATTAGATATATGGTTAATGCTGGTGTCTATGATGAAACTGGTATTATGATTAGTTCTAACTTCCGTCGTTTTAGTTTGTTGAGTAATCTTGATTTCAATCTGTCAACAAAGTTGAGTGCTTTCACACGTATTAATCTTACATATGCTACGCAGAAAGCTGGAGCAGATGGAGGTCGTGTGCAGGGATTGACATTCGATCCGAAACGTACATCGACTCTCTTGCCGGGTAAGGGTAGTACTGCTGAGCAAGTGGCATTGAGGCAATTGAAGGATATTGATAAGACCAACTCAAACTATAATGTTCGTTTGAGTGTTGGTTTGAACTATAACATCTTGAAGGGTCTGAAGTTCTCTTCTACTTATTCGCTTGACCATTACTTCACACGTGTATACACGTTCACACCTGATTATCTGAAGTATGATAAGAAGTCTGAGGTTCAGGCTTCCAATATTGCAATGACGAATATCCAGACAGAGAATATTCTTACTTATAACTTGGCATTACCAAGTGAGCATAAGTTGGAGTTGATGACTGGTATGACATATAACTATGACCTGTTGCAGAACTTAAGCGGTACTGCAAAGGGCGGTCCTACCAACTCTATTAAGTATGCAGGTGAGGGATGGCCTTCACTCTTTAATGATGGTGGAACAGTAAGAGCAGCACAGAGCTTCCTCACTAACCAGCAGGAACAGTCATTGCTCAGTTTCTTAGGTCGTGCAGCTTATAGCTATAAGAAGCGTTACATGGCAGAGCTTTCTATCCGTGCAGATGGATCAAGTGTGTTCGGTAAGGACGTACGTTGGGGTACCTTCCCTTCTGTTGGTCTTGGTTGGGCATTCAGTGAAGAGCACTTCATGAAGAAGTTCTGGTGGTTAAGCTTCGGTAAACTTCGTGCTTCTTGGGGTAAGTCTGGACAGAAGTTCCAGGAGCCTTATTTGGCATTGGGTGTGATGGAGGAGAGTAACATCTTTAACGGTTCGTTAGGTCTTATCCCGCAATCTATGGCTAATAAGAAGTTGACTTGGGAGGAGAGTGACCAGTATGACCTCGGTCTTGACTTGCAGATGTTGGATTATCGTTTGAAACTCAAGCTCGATTATTACTATAAGTATTCAAGCAAACTGTTGATGCAATCTTATCTTCCAGGTAATGTCTTCCTTGCTACAAATATGTGGGATAATGCATCTGCTATCTCTAACGAAGGTATCGAGTTCGAGGCTCAGTATGATGTTATCCGCAAGAAGAATTGGAACTGGAGCGTAGGCTTCAACCTTTCTCATAATAAGAACATGCTGCGTAAGACATACAATGGCGAAGACCTTAATGATAAAGTCTTAGGTCGTCCAGTCTATGGTATCTATACTTTCAAGGATGAGGGAATCGTTCAGAAGGAAGAGGATATCCCAATGTATCTTAATGCATCAGGTAAGCAGATTCCACTTTACTTCCAATCAATCAATAATCCATTGCGTGTGGGCGGAAGAAAGATTAAGGACCAGAACTATGATGGTGTGATCGATGATAAGGACCTCTATTATGCTGGTAGCACACTTCCTGCAGTTTATGGTGGTTTGAATAGCCACTTGGAATGGAAGGGATTGAGCTTTGATGTACTCTTCAGCTATACCATTAGCCGTAAGGTTATGAATATGTATAAGAACAGTGCCTTCACCTTTACAAAGGACTTCGGTGTAATCATGAACTACTTCCATGCTGGTGACTTCTGGACAACAAGCAACAGAGATGCGAAGTATCCATCACTTGAGTTTGCTGATAAGGATTATGTAGGTCAGTTTGACGGTAATGTAGACTCTAACATCGAGAACATTAGTTTCTTACGTCTCAAGCAGTTGGTTATTGGTTATCAGATACCTAAGAACTGGTTGAAGGGTTCTTTCATCAAAGATGCTAATGTTTACCTCAGCGGAGAGAATTTGTTCTTGCTTACCAATTACTCAGGAGTAGACCCAGAAATTATTAATCCTTATTCTGGTAAGGACGATGGAACACAGTATCCATTGAATAGAAAGGTTACTTTGGGTCTCAACTTAAAATTCTAACAGAAATGAAGAAGATTATAATGCTCTCAATATGTGGTTGTCTTCTGTCCTCTTGCAGCCTTGACTTGCAGCCTGAGAACGGATTGACTTATAGCAACTCGTTTAATAAGGAGAAAGAGCTGAATGCAACAACCACTTCTATTCTATATTATATCAACACTGTTGTAGGTAATAATTACGTTCTTTCAACAGCTGGTATGAAGGCTGACGAGATTCTTGATGGCAAGCAGTTACGCGAGTGGAATCCACGAACAGTAATAAAAAGTGAGTATTCATGGAAGGGTCTTTACGACATTATCTTTGAATCAAATCTATTGCTTGATAATATAGATAAGACAAAAGGCTTGGCTGAAGATCGTCGGAAGTATCATGTAGGGCAAGCTGAATTCGCTCTTGGATTGTCTTATTTCCTTTTGGCACAACGTTATGGTGAGGCAATCATCACTGATAATTCTTCAGAGATAAAGCCTTACTCTCTCTCTTCACAGAGTGATGTGCTTAATGCTGCAATAGAACATGCAAAGAAAGCATTGGATATTTTGCCTACATGGGATAAGTTGACAGACTTGAATGGTGTTTCTATCACTAATCGTCAGACTGCTTCAAAGGGTACTGCTGCAGCCTTACTCGCACAGATTTATGCGTGGAAGGGTAGTGTGACAGAACTTTATAAGTTGCAGGGTAATGCGCAAGAAGATTATCAGAAGTCTATCGATTACTCAACACAGGTTATCGATGGTCAGGTCGGTAATTATCAGCTTTGCTCTTCACCAGAGGAACTCTGTACGTATCTGTCTAATGAGAAGTCTCCTAATCCAGAGGCAATCTTCAGCTTGTACTTTGATAAGACGCGCTCAGAGAATGTAGTTTCTCCTAATGAGGTGGCACAGAACTTTGTGAGCTGGCCTGTAAGAGAGGACCAAACATTAGCTGATTTACCATCAAGTAGTACCTATCAGCTTTATACTTCAACAATAGAAAGATTGTTTCCTGATGCTACTGACCAGCGTCTACAGGCATTTTTCTATCAGTGGGGTACCTCACATGAGGTAGATGGAACTGATTACGCTATTATGTATAAGTTCAGAAAAGCAATTATGGATGCCGATCAGTATTCTGCAAGTGGTAAGACTTACCGTACGGTAGATGCTGACTATGTTTACTGGCGTCTTGCTGATTTCTATCTCTTGAGAGCAGAGTGCTATCAAAAGTTAGGTAATGAAGCAAAGGCTATCGCTGATCTTAATGTGATTCGTTCACGTGCTGGTGCGCTTTCTTATCCTTCAACCTATGATACAGAGGGACTGAAGAAGGCTATCTTCCTTGAAAGAGAAAAGGAGTTTATCGGTGAGAATGATGCACGATATGCAGATGTTATCCGTAATGGCTATGTGAAAGAAGAGTTACAGGGTAAGTTCCGCTTGTTGACTAATCAGGATATTCAAGGTGGTGCACTCTTCCTTCCACTTCCAAAGGATGCATGGCAGGATAAGGATGGGCACATCATTAATACATTGTTGCGCCAGAAACCTTATTGGCAGGCTTATAATTAATGATGGATAAGGATTGTACAAATCAAAAAGTGTTCGATATAATGAAAAAGATTATATATATAATAACAATGTGTCTGACAATGGGAGTCTTCTCCAGTTGTACTCAGTATAACTTTGACGACACTGGGCTTGCTAATGGAAAGCATGATATGACGATGTGGGAATACTTCAAAGGGGACAGCTATAATTGGGATTCCCTTCGTGTAATGGCAGAACGTGCCGACTTAGTGTCGCTCTTCCAAGGTACAAGTCAGTACGGAAAGAACTTCACATTCTTTGGTCCTACGAATCATAGTATTCGTCGTTATCTCTATGATAATCATATGGAGAGAGTGTCGGATATCCCAGTTGCTGACTGCAAGAAGTTTATCTTGAATAGTGTTTTGCCTAACAAGCGAGTGATGCTTGATGATTTTAAGGAAGGTGTTAAATCTTCTGATGCATCAACACCTATTGGTAAGGGAGGTGAGACAGTAGAGATGGCTTCTGGTAAGCAGTTGTGGATTTATACTTTCCACGAGTCTTACAACGGTGTGCCAGCCGCTGGCCCTTTACGTATCCACTTGGTTTCCCCAACGACCACCAAGACTTCTGACGTTGCTTCATGTAATATTGAAACAAACACAGGAGTGGTTCACTCACTTGTTTATGACTTCAACTTAACCGACTTTTAAAAATGAAAAAGATGAAGAAAGGAATCGCATTGCTATGCCTTATGGCCCTTACAATAGGTTTTATGGTATCATGTAGCAAAATGGATGTAGGCTATCTGAGAACAACTGGAGCATCTTTTACTCCCGATTCTCTTAATGCCTTCCATAACGTCGATGCAACGAGTGAGCGTGGTATCAATAAGTTACCATTCGTTTCAACACGTATCCAAGGTGTTGCAGGAACCAACCCTATCAATTATGAGTTGTTTGGGGTTAAGGCTGACAATCAGGAACAAGCACAGTTGTTTATGAAACTCTATAAGGAGGGTAAGATTTCTGTTACTGGTGGTCTGATTGTTGTCACACAAGAAGCTACGCAACAGTTGGCAAACGGCAGATATCGTCTCTCTCTTAAGGTGTATAATCAAGACCATGAGGTAGTCTTGGAAGACATCTTTAAGGTGGTAGTAACAGATGATGAACTGCCTGTCGAGTAATTTCGATAAAGGTATATTGTAGATGTATATACTACGTTCAGCATTGACTTTAAGCGTATTCCTCTCATGTATTAAAAAGATAGATATGAATAAAATCAATGCTGTAAGTAGGATACAGTTTAATGAATAGATTGAATAAAATAATCCATTAAAAACAGATTAAATATGAAAAGAAGAAGATATATCTTACTGCTTGTATCTCTTTTGATGATGGTAGTACAGCTTCGTGCACAGCAGGGTATGGAAGCAGCAAATGGTATTAAGTTCTTTAAGGGAACTTTCAGTGAAGCTTTGGTAAAAGCTAAGCAAGAGAATAAAATTCTGTTTGTTGACTTCTACGCAGTGTGGTGTGTTCCTTGTAAGAAGATGGCAAAGACAGTTTTCACACAAGAGGAAGTTGGAAAGTATTTCAATGAACACTTTATCAGTCTGCAGTTAGATGCAGAGAAGGGTGAGAATGTTGATATCGCTAAGAACTATAAGGTAGCAGCATATCCAACAGTAGCTTTCATTGCACCAGATGGTAAGGCCTTGTCTGTGAATACAGGTGCGATGGATAAGGATGAACTCATGGAGGCTGCTAAGATTGCAGCAGGTGAGAGTGTAAGTTTTGAGGAACTTTACAATAAGTACAAGGCTGATAACAACGACCTTGACGTTCAGCAGCAACTTCTTCTCAAGGCACCATCTTTCTTGCAGGCGCAGGAGGGTATGGATGCAGATAAGTGGGTAACACGTTTGCAGAAACTTTATAAGAACTATGTAGCTGCTAAGGCACCATTGAAGCTTATCAATGAGAATGACTATCGTATCATTCTAACATTGGAGGGTGATGAAGATAAGGAGCACAAGCAGTATATGATTGACCTTATGAACGACCACCTTGATGACTGGATGAAGAAACTTGGTAAGGCACCTGCCTACTACATTGTTGAGGCTAACGACATCTTTGCCGAGGATATGGCAAAAGATGGCAACGTAAAGTATAAAGACTATGTAGAGAAAGTTAAGAACCAGTATGCAAAGGCATACGAGGTTGTTGGCTTGACAGGTATTACTCCATACGAGAAGGCAAAGCTCTACTTCGATGCTCTTTTCAACTTGTATAAGAACAAGAATGTGAATGGCTATGTGAAAGCTATGGAGACCTATTTTGGCAAGATGGAGAACAACCTCCGTTCAGCCGACTATGGTAAGGCAGCACAGAACCTCTATATGGCAGCAGGCAAGAGTCTGAAGGCTAAGGATCATGAGGTAGCTATCAAGTGGGCTGAGAAAGCTTTGTCACAGGAAGATGCTGTGATGGACCGTGTCAACTATATGGTAATGATAGGTGACTCTTATCGTGAATTGAAGAACTATACCAAGGCACGTGAATACTATAACCAGGCATTTGCTGAGACACTCCGTTTAGAGAATATGGAGATGCCACAGGCTATGTTGCAGGGTGCAATCAAGCAGAAGCTCTCTACGCTCGAACTCCTTGAAAAGTAAACAATGACTATGTTCAAGAATATCATTAAATGCCTATCGAGCGTGCCAGTGGCACTGCTCATAGGCTTTTTGTTTTCCCCCCTTAGTTCTGCCAATGCGCAGATGAATGGATTGCGAAAGGGAAAACTGGCAAATGGGCTTACTTATTATATCTATAATGATGGTTCTGCTACTGGTGAAGCACAATACTACCTCTACCAAAATGTAGGTGCTATCTTGGAGAATGATGAGGAAATGGGATTGGCGCACGTGTTGGAGCATTTGGCTTTTAATACGACAGACCACTTCCCTAATGGTGTGATGAACTTCCTTCGCAGTAACAATCTCAATGACTTTGAGGCTTTTACAGGTGTTGATGATACGCGTTATGCGGTTCATAACGTACCAACCAATGATGCGAAGCTAAATGAGAATATGCTTTGGGTGCTCCGTGACTGGTGCCATGGCGTCAAGATGACCCCTAAAGACATTGAAAAGGAACGTGGTATTATCCTTGAGGAATGGCGTCATCGTTCGGGAGTAGACCGTCGTCTGACAGATGCCATTGCCCCTGTTGTTTATAATCATGCTGGTTATGCTACTCATAATGTGATTGGTTCACAGAAGATATTGGAGACCTTCCAGCAGAAGCAAGTAAAGCAGTTTTATGATAAGTGGTACCGTCCTAATATGCAGTTTATTGCTGTTATCGGTGATGTTGATGTCGACCAGATGGAAAAGAATATCCAAATAGTTTTCAAGACATTGCCAGCTAAGCAAGCCTCTGCTGTAAATTCACAGACAAGACAGATTCCTGACAATACCACACCGCTCTATATGCGTTTCATTGATCCAGAGAACAAGAGTGCTTCTTTTGGTCTTTATCAACGTTATGAGGTGAAGGGCAACGCTCCAGAAGAGGACCGAGTACGTCAGTTTATCTTCACTAAGTTCTTCAACACATTGGCTCCAAAGCGTTTTGTGATGTTGAAGAATGCTGATAAGGAGAGTTATATTGCCGCTGAGGTGAGTCTATCTCCTTTGGTAAGAAACTATTATCAGATGGCATGGGACATGGTTCCCTATCAGGGTAATGAACAGAAGGCGCTTCAGCAGATGTTAGCTGTACGTGATAACTTGCGCGACCAAGGCTTTACTGCTGCTGAGTTCAATGCTGAGAAGGAGAAGATGTACAATGGAATGAAGGATGTCCTCGAAGCTAAAGGACTGGGTACACCAGACAATGCTTTGATGCTTTTCCGTCAGAACTTCCTCTATGATATTCCTGTACAAGACTTCCGCGGACAGATTAACCGTAACCTCGAAACTTTGGTTGAGTTAGAGGTTGAAGACATGAATGCTTGGATGAAGTCATTGCTTAATGACAATAACCTTGCTTTTGTCACTTATTCTAAGTCGCAGAGTGAGATGAATATCACTGAGAATGATCTTATGGCTGCATTGAAGGCAAAGAGCTCATTCAGCGATATGGCTCGCGCTGATGGTATGAAGCCTATCAGTCAGTTGATTGACTTCCCTCTGACAGGAGGAAAGATTGTTTCTGAAAAGCAGTTGAAGACTTTGCAGGCAAAGGAGTGGACACTCTCTAATGGTGCAAAAGTTCTTTATCGTAACGTTCCGGAGCTGAGTGGTCAGTTCCTTTTTGCTGGTTCTGCAGAAGGGGGTAAGTCAATTGTCCCAGCACAGGAACTTGCCAACTATAATGCAATGCGTTCACTCTTGATGCAGTCAGGTGTATATAATTACAACCGAAATCAGTTGGCGCAGTGGCTACAGGGTAAGAATATCAATCTCTCCCTCTCATTGGAAGACTACAGTGATGGTATCGGTGGTAATGCACCTGTTGACAAGGCTGACGATTTCTTCAGCTATCTGTATTTGATTCTGTCACGTCAGAACTTCTCAAAGTCTGCCTTTGATAAGTATGTCCAGCGTAACTTCTACGTTTATGAGAATCGTGCAACAACAGGTATGGCTGCCGTACAGGATTCTATCCAGCAGTTACTCTATCCTGTTAGTGCGATGAATCCACGTCAGGATGAGGCTTTCTTTAAGTCAGTTCAGTTTGATAAGTTGCAGGAACAGTTCCAGGCACACCTTGGTGATGTATCACGTTTCACCTATTGTCTTATTGGTGATATTCCAGAAGCAAAGGCTAAAGAGTTGGTGCTTCGCTATATTGGTTCTCTCAAGGGTGAAGGTAAGCCTGTGAAGACAGCTATCCAGCCAATGGACTTCTCTTCATCTACGCCAGTCATTAAGCGTACTTTTGAGACCGAAACAGAAGGTGGTATGGCAGAGATTGAGATTTCATTTGCCAATAAGCAGAAACTTTCTGAGCGTGAGCAAGCTGCTTTGGAAGTGATGCGTGGACTTTTGGAGCGTCGTTATTTTGATGTATTGCGTGAGAAAGAACACCTTACTTATACCGTAGGTGTACAGAGTAACTATACTTCACAGCCAGTAGCTGGCGAGAGCCTTAACATTCATCTTTCTACTGCGAAAGAGAATGCTGACAAAGCTGTTAGCCTTGTTTATAGTATTCTTGATGATGTGAAGGCTGGCCGTTTCACTGCTGATGAGTTCAAGGCTGCAATGGTACCTTTGGCTGTTGATGAGGAACAATCAGGTGCAGCATCACAGTCAAACAGTGACCCATCAGTTTGGATGGCTTTATTGAACATCTATGCTGAGACGGGCAACGAGCTATCTCCAAATGATAATGCCGCTTCCGCACCAGTATTCAAGACCCTCACACCACAAGATATCACTGCTGTAGCTATGAAAGTGATGACAAATGCTAAGCAGCGTGAGATTATTGTTAAGCCTGCTGCGCAGGAAGGTAAGCATACCTTTAAGTAATTAATGGTAAGTAAATATAAAAAAACAGAGGTGTACCAAGAGTGCACCTCTGTTTTTTTGACTTTGTACAAGATGTACTGAGACCATTAATGGTCTATTCTATTATATTGCTGTCCGATAAAACCTCCATATACTGCAATATCCTCTCTCAATCCTGCTGAAATAGGCATGATTAGTTCTAATTTCAAATTCCAAGCCCCCTAGAATAATGACAACTCTTCTGGTGGGGCTTTTACTTGGGTAATCAATCTATCCCAGTCTCTATGTGGCTGCTCAAAGAAACTTTGTATTGCGACATAACTCATAAGTAAAATTCTTATCATTGTTGCCAAGCCTGAGAAGCTCCAAGGTCTCTTTATTTTGTTCTTCACTAGGGTTATAAGCAGATTGGCTATAAGCGTAATCCATATTTGTATTTTTATAGCATTCGCACTCTCTCCATAGAAGTATCTTAGCGGGAAATTCTGTTTTATTTGTTTAAATAAGGTTTCTATTTGCCATCGTCTCTTATAGATAGCTATAATATCTTCTACCGACATCTGAAAATCATTGGTCAGCAGTGATATGAATCTGATTTTCCCTTTCTTGGTCTTATCCTGATATGTGATTTTTCTTGCTTTATGGTAAATATCTTTTTCCTTTGTATGCTTATGGAAGAGAATGGTTTCTACGCGTACAACTCCATAATCTGTAGTCATCTGGTAATCCGTATCAGCAATCCTTTCAAAGCTAAGATTATTTTTCATCTTAGTTACATATATAACGCCTCTTTGAGTCAGTTCAGAGAACTTTTCATAGTTTATATAGGCTCTGTCAAAAGCAATCAGTTCCTCATTGGCGTATCGTTCTGGGATAAGTGCAAATTGATCATGACTAGCTGCAGATGTGAACTTGATATCGCTTGGAACATTCTCATTGGCAAATATCTCTGTATGTACTTTTATTCCACCCTTCTTCTTACCAGTTTTGGGATTACGTCCTACTCCTTTAAAGACCAGGTTAGAAAACAGACTGATTGTCGTAGAATCTATTATCTTTAGATTCTTCAGCCATTTGGGCTGTCCACAATTTCGGCTGTCCGAGTAAAGTTCATGGCGATATTTCTCATATAAGTTCATATAGATCGAACCGAATATCTCGGAATCTCGGCGTTTGTTTGCATCTGACAAGGTACTTCGACAAGGAAAATGCTTTAAACCAAGATGATTAAAGCGATTAACATTAGCAAAGAGAGAGGCCTTTATCTCACGCAGAGAGTCTAAACGCATCATTACTGCATAAAGCATGACGACAAGATGATGCCATGCATCAAACTTCTTTATATAGTGTTCACCTCCCTGAGCTTGGCTCAGAGAGAGAATTTTATCACGATTAAAATAGTTTAACAGTTGAACATATAGTGGCTGTCCGATAAAATGTGTACTTTTGTTCATCTTATTTCATTGTTTTATTTTGACAACTACAAAGGAAATAAGAAGGGCTGAATGTGCAAAACAATCAGCCCGTTTTTTTTATTATTCTGAATTAAAAAGATATGAACGCAAAAAAAGTTTTATCGGACACCAATAATTCTATTATTATCCTCCGATACAGAAAACCTTTTCACCTTTCTACTTAAAAAACGCAGGTAGGAGTTTGAAAAATCATTACATGTTTCCAAACAAAAGCTCTATAGATAACGGTAAAAAGATGTCAAAAAGGTGTGTTTGTAACTTACAGGTAGTCAGTTAGTTGTAAAGTAATGTAGCGAGCGGTGCCTAATTGGACTTCAAAAGGGCGTTAGTTAGCCCTCAAAAGGGCACCTATTGCAAGTCAATTAGGCGTCTTTTAGAAGCCAAAAGGGCATGTCTTGGATTTGAACTATACGAAAATAGTTTACAAATATCGCTTTGTAAGGGAGATAGATTGATTGTAGAAGACGAATAGGCATAGTAACAGGAATTACTTTCTCTTGTGTCCAGCACTCCCCTCTCTCTTGGAGAGGGGTTGGGGGAGAGGTTTTTAATAATCCTCCTTATATTTATCTGTCTCAATATAGATATAAATTTTGTAGTCTGGGAAGGCTGCCCGCATATTCTTCTCAATGTCATTAACCAACTGAGGAACTTGTGCTTCGTATTCGCTTTTAATATCAATCTTTGCAGTGACAAGAATGTCTGTAGGACCGAGATGAATGGTCTTGACGTTGATGAGGCGGTCGATTTCTGTTCTGTTGAATGTCTCTTTGATACGTGTCAGGTCCTTCTGTGTGACACTCTCACCAATAAGTAGACTGTAGAATTCACGTGAGAGGAAAAGAGCTGCTGCACAGAGGAGTACACCAATCAGTACACCCGATAGGGCATCATAGAATGGATTACCTGTGAGGTGGGTCAGAAGTGTACCTCCTAAGGCTATCAGTAGACCAACGACAGCACAACTATCTTCTGCAAAGATGATGAGAATTTCGCTGTGACGGCTCTCTCGTAGGAAACGATAAAGTGAAAGATTGTCCTTATTCAGTTCCTTAATCTCCTTGAAGGCAACCCTTAGACTGACAGTTTCTACTAAGAGTCCGAAGGCCAGAATACCAATGACGAGCCATGTGTTCTCCAAGCTGTGTTCTGGGTGAAATAACTTCTCTGCTGCTTCCATGATACCTAATGCACCACCAGCGAAGAATAGCATCATTGCAACAACCAAGCTATAGAAATACTTAGCACGTGCCTGTCCGAATGGATGTTTATCTGATATCTTCGCTGTTGACTGTCGGTTGCCTACTAACAGTAGTATTTCATTGCCACAATCTACGATACTATGGATAGACTCATTCAACATTGCAGCTGAGCCAGACACAGCAAAACCAACAAACTTTGATATCGCTACCAAGATGTTTGCACCTAAGGCAGCGATAACACTCATCATTCCTTCACTTTTCTTTTCCTTTTCCATATCCTGTTTTAAACTTTTTGATATTGGTATATATTTACCAGATGTATTCTGTAACGTACTTACTATTTTCCTCTTTGTTATTTTTATTTAGTGTTGTCACCACTTCTTCAATGCGGGTGGGACGTCCTTCCTTATCATACTCCGTTGTCAGTTGCGACTTGAAATTGAAGTCTTTATCTTTTGAACTAAAGCTATAGCTGCTAATATCTCCTTTCGGAATAACACCCATATAGCCCAAGGTGATGAAGGGGATGGGTATTCTTATACCACTACCAAACATCCAAAAGTAATAGAGGTTATGGTAGTTCGTTTTCTCTCCAGTATCTCTGTATGTGATATTTAATGATTTGTCAGGTAATATCTTCTCTCCCTTCCATTGGAGGATGTTGGTTTGTCTCCCACAGAGTGTGTTAGGTGTGTCACGACAAACGAGTCTTCGCTTATTGTCGTAGGTGTATGTATAATAGCCGGGAGTGTTATTCGCTTCTACGATAAGTCCGTTCTTAACTATATAATAGCCATCAAGGAGTTCGTCTAACTGGTCTTTAATATGCGTCTTATGAATGTGAATGGTATCACCAGCATAGGAGTAAGTGTAATCATCCAAGCTGTCTGTACCCACACGCTCTATGATGAGCTGCCCTTTTTGGTTACAATAATAGGTGATAGTGTCCTTACTCCTCTCCGCTTTCGATGTTACGTCTTTGATAATCGTCAGATAACGATGCAGTTGTTCTCCGTGATAAGTTATCTCTTCTGCTATTCCAGAAGGGACAGACGAACATGAGAAAAACAAACTAACAACTATGATAGCTAATAAGAGCAGTCTGATGTCTTTGTATAAGTCTTTCTTCATTTGTTCTTGATGGTTAAGGAGTTTGTTTATATATGCGGAGTTCTGCAATGTTGAATAGGAGATAGTGAGTAGCAGTAAGGGACAAATACTTCTCTTTTAGAGGGAAAACGAGCTTGTTCAAGTCTTGTTCTTCGTACAGTTAGCCTTACTTCTTCGCAGCCTTCTGTGCCTCTTTCACCATCTTTAGACGTTCCTCGTAGATGGGGCGCCACTTGTTGATCATTGCTTGAAGGTCTTTACTTCTCTGCTCCAATTCACGGTATTCGTCTGTATCTGTTTCGTTGTTCTGACTCTTCATTAGCATCTGTTGCAGCATTAGTTTCTGTTGTTCATCAGCCTTTTGAAGCTGTGCACCAAGCTTTTCAAGATTCTCCATAAACGCTAATGCACGGTCAATATGATTTTCTTTTTCCATCTTTTGACTATCTTTTAATGTCTTTTTTCTGCGTACAAAGTTACAGAAAAAGTTCAGTATCACCACTGCTTCCAAATTATTTTCACGAAGAAAAGAATTTCTTTTCATGAAAAAAAATATTTTTCTTCACGTAAATAAATTTTTCTTTTCATGAAAATAATTCGCAGTTGGTTGTTTTCTTTGTAATCTTCGTGTGTAAGACGGGATTTTATAGTATCTTTGCAAGTAGATAAAAGAACACATTTAGATGGAAAAGAAGAAACAGATAGATTGCTTTCTACCGTATAGCACAACTGCAATGATGGAGTCACTTGCTGCGCAGTTGTACGAGTTAGGTGTGGTAAAGAATATATATACGTTAGCTGCAGATGTCCTACCTACAGAGGCATTGCCTCTGTACACCCATCAGCTGCAGACAGGTGGTTTGCTTTCCCTTGCTACTATGCGCCTTATAGCGACTACAGCAACAGCCGATTATGCCCTGCTTTATTTGAAGCAAGGACCTATCACGTTAGGTTATCATGCGCTTGAGCGTATGCTGCAAGTAGCTGAGGAAACTGGTGCGGGAATGGTTTATGCTGACCATTACTCTGTGAAAGTTGGCAAGACGGTGAGGCATCCTGTTACAGCCTATCAGTTGGGCAGCATCCGTGATGACTTTGATTTTGGTTCTGTCGTACTTCTCAAGACTGGGTATCTGAAGGAGTATGCAACAAGAGAGGTGGAAAAGGACTATCAGTTTGCTGGTTGGTACGACCTTCGTCTATTCTTAAGTCGTAAGGGAGAACTCTTCCATCTGAATGAATATCTCTATACGGAGGAGGAAGACGACCTACGTGCAAGTGGCGAGAAGCAGTTTGATTATGTGAATCCACGCAACCGTGAGGTACAGATTGAGATGGAGCAGGTGGCTACAGCACATCTCTCTGCTATCAATGCCTTGGTAGATACAACGCAATATGCACAGCCAGACTTCTCTGCTGAGGCTTTCCCTGTGGAGGTGTCGGTGGTGATTCCTGTCTTTAATCGTGAGAAGACAGTACGCGATGCGGTTGTATCAGCACTCTCACAGAAGACAGACTTCCCTTTTAATGTCATCGTTGTCGACAACCATTCGACAGACGGAACGACGGAGATTCTCTCTACTTTGGCTGCTGATGAGCGTCTTGTGCATCTTATTCCTACACGCACAGACCTCGGTATAGGTGGCTGTTGGAACTATGCTATCAATGATGCGCATTGCGGTCGCTTTGCTGTTCAGTTGGATAGTGATGATCTTTATTCCTCAGAAAATACTTTGCAGACCATTGTCGATGCTTTCCACGAACAGAAAGCAGCGATGATAGTAGGCTCTTATCGTATGTGTGACTTTGATCTTAACACCCTTCCACCAGGTTTGATTAGCCATAATGAGTGGACGGAAGATAATGGTTGCAACAACGCCCTACGTATTAATGGGCTCGGTGCACCACGTGCTTTCTTCACTCCTTTGGTTCGTCAGCATCAATTCCCTAATACAAGTTATGGCGAAGACTATGCTATGGGCTTGGCTTTCAGTCGTCGTTTCCGTATCGGACGAATCTATGATGAACTTTATCTCTGCCGTCGTTGGGGTGGAAACAGTGATGCCGTACTGAGCATTGATAAGGTTAATGCCAACAATCATTATAAAGATCAGCTGCGTACAGTTGAGATTTTAGCACGTCAGAAACAGAATCAAGATAGAGAGAAAGGGCTAACTGATTTTTTTCATAACCAGCTGAACCAATGGAAAGACGTTGCAAAACGTTTTGAAGAGTTGAAGGGTGTGCAGACGCGTGAGGTGGGTTCAGCCCTTGCGCAATTCAATCCTGCACGCTTGGTGAGTACAGGTGCGAAGATTGATAAGGCTACACTGGCTAAGCGTCCTTGCTTCCTTTGTGAGAAGAATCGTCCAAAAGAACAGATTGTTCTGCCTTTTGGAAACGACTTCGATATCCTTGTCAATCCTTTCCCAATCCTTCCAGTACATTTTACGATACCTTCTCGTCATCATCAACAGCAGGCAATAGCGGATAATTACGTACAGATACATCGCTTGCTAAGAGCTTATCCGCAGCTGATGGTATTCTATAATGGACCGAAGTGTGGGGCGAGTGCACCTGATCATCTCCACTTTCAGGCAGGAACAAGTGGTATTCTCCCTTTACAACGTGACTGGCAGTGGCTTTATGCGACCTCTGTTCCGCTCTTAAAACTGAATGATGTGGAGGGAATCTACGAGATAAAAGACTATATCTGTCCCGTTTTAGCTATCGTGAGTCATACAGAGAAGCACGATGTTGAGCTCTTCAGCCGTTTATATGAGGCACTTCCAATGAAGGAAGATGAAACTGAGCCGATGATGAATATCGTGGCTTGGCGCAGTGGGGAGGCATTTATTTCAGTTGTATTCCCACGTGAAAAGCATCGTCCTGATTGTTATTCTGCTGACGGAGAGGCACAGTGTCTGGTTAGTCCAGGTAGCTTGGATATGGCAGGGTTGATGATATTGCCTCGTCAGATCGACTTCGAAGGGATGACAGCAGAGCGTGCTAAGGACGTTTTACAAGAGGTTTCACTGTCAGATGAGGCAATGAATGAAGTCGTGAAGCGTCTTCGCAATAAGGCAGTTGACCTCGCTTTCGATGATTGGAAGTACGAACCGATTGTCTCAGTAGGTATCGTTAGCGGCGACGAAATACGTTTCCAGCTGAATGGTACTTATACAATAGGAAACAAAGAGGTGACTGGTAAGCAGATTGTAAAGTCCAAAGATGGACAGATTCTGTGGAATTCTACGGTCTATCAAGAACTTTGCTTCACCCCGCAAAATGATGATATATCCTTTACTTTAGAGGATGTTACTATCGGAGTAGACTTCCATTGGGAGCGCAAAGAGGCACAAACCTTCCTCGGAAAGCTACGTTTTGTTGTCGATGGAGATAAGCTCTGGGCTATTAATGAACTACCTGTAGAACGTTATTTAGCAAGTGTTATCTCAAGTGAGATGAGTGCTACCTCTTCATTAGAGCTTTTGAAGGCACATGCTGTAATCTCTCGCAGTTGGCTTTTGGTACAGATGAGAAGACGAAAAGCTATCGAAATGGGTGTTCAGACAGCATCTGCACCTGTAAAAGTGTCGGATGAAGAAGGTGTGGTTTGGTATGATAGTGATGCTCACACACTGTTTGATGTCTGCGCAGACGACCATTGTCAACGCTATCAGGGTATTACAAAAGCAACAAGTCCGCATGTTGAAGAGGCTATTAAGGCTACACGTGGTCAGTTGTTGATGAATGGTAAGGGAATATGTGATGCCCGTTTCAGTAAGTGCTGTGGTGGTGTTTCAGAAGAGTATGAGTACTGTTGGGACAATAACCATAAGCCTTATTTACTCTCGATAGTGGATAATGCACCTTTAGGAACAGCTCCTACAATTGACCTCACGGATGAGGCGGTGGCGAGGGAGTGGATTCTTTCTTCGCCAGAGGCGTTCTGTAACACAAAAGATGCGACAGTCTTGGGTCAGGTACTTAATAACTATGACCAAGAAACACAAGACTTTTATCGCTGGACAGTAGACTTCACGCAGTCAGAACTTGCTGAACTAATCCGTCGTAAGAGTGGTCTTGATTTCGGAGAGATTATTGACCTCCAACCTTTAGAGCGCGGTAAGAGTGGTCGTATTACGCGTTTGAAGATTGTAGGAACGAAGCTCACACGTATTATCGGTAAGGAATTAGAGATAAGACGCACGTTAAGTGAGAGTCATCTCTACAGTTCTGCTTTCGTGGTAGAACGTAGTGAGATTGTGAATGACATCCCACAGCACTTCCGTCTTGTTGGTGCAGGGTGGGGACATGGTGTTGGTTTGTGTCAGATTGGTGCTGCTGTGATGGGCGAGAAAGGCTATCAATATGACGAAATCCTCCATCATTATTATCAGACAGCAGCTATTGAAGCACAATACAAATAAAGCATACGAAGATGCACGAGGAACAGAAGATAATCAATGGAATTCCTATTGTAGACCAGTGGCGTAGCTATTGGCTCTGGCTTCCTACGCTCTATTTGACACGTGGACTACCGTATGTTATCTTGTTGATGACTTCATTAGTCTATTTCAACAGAATGGGCTTGTCGAATGGTTCTATCACACTGACGACATCGTGGTTAATACTGCCCTTTATCCTCCGACCTTTGTTAGGTAGATTGGTCGTTGGCTATTGGAGTAAGTATGCATGGGTAATTCTGACAGAGTTTGTTATGGCACTGAGTCTTGGTGGATTGGCGTTTATGGCATCATCTGTTGATTGGTTTGAGTGGACAGTCTTCTTCTTAATGATAATCGCAACGATGGCTGCCTTACATGATGTGGCTATCGAAAGACTGTATAAGCGTGAAACGGTCTTGCATAATCGTCCTGCTTTTATTGGTACGCGTGCCATTTCTTATATGCTTTCTATCATCGTGGGAATGGCTATCCCTGTTACAATAGCAGGAAACTTAGAGGTCATTTATAGGACGGTAGCCCCTTCATGGGCAACTATTTTTAGAGTTCTGTCAGTCTTATTGACCTGTTTGATGCTACTTCATGCTATCATACTTCCCAAAGATAATATTCATGCGAACCTCCCTATATGGACAGGGGTGACACGTCAATGGTGGCATGATGTCAAGGCTGCCTTTGTCCGCCATCCTCATTATGTGGCAAACTTGTGTTTCCTTTTTGCCTTTCTCATACCCGAAGGGATGTTTTTTAGAATAGCACCACTCTTTTTGATAGACCCAGGAAGTAATGCAGGATTGGCTCTTTCACCACAGGAGTTAGGATTAGTCTTGGGAACAGTGGGTACGTTCTCGTTAATTGGAGGAAGTGCCTTAGGTGCTAATTTGGTACGTCGTGACGGCTTGAAGCGTTGGTTGTGGCTGTTTGTTATAGCCTTGACCTTGCCAAAGTTTGTCTTTGTTTATCTCAGTTATTACTTTGTCTCCACCTTATCAATTATCAATTTGTGTGTGATTATCGAACAGTTTGGAGCAGGTTTGGGATTAACGTTTTATGTTGTATGGCTCGCTCATTGTACAAAAGGGGAGCACTCCACATTTACTTATTCAATAGGTACGGCAATAACAGCCTTCTCGTTGGTGATGACAGGATGGTTTACAGGTTTCTTGCAGGAGTATGTAGGCTATCGTCTATTCTTCCTTCTTGTGGCAATGTTGGGTGTTATCAGTTTTATAGTGACCTACTTTCTCCCTGTAACAAAGGAGATAGGAAAACGAAAAAGGATGGTTTAAATCCATTTAAAACGACGGTTCTGATGTTTTGTTTTCAGCCGTTAACCTTTATAAAAAGGTCATGATTTTATTTGTACCTCACGAAAAATGTTGTACTTTCGCAAGTAGATAGTTATAAAAAACAGTAAATAAAATGAAGATTAAGTATTTCTTAATGGCAGCTGTTGTCGCTTTGATGACAGCCTGTGGTACGGCTTCAAAGGTTCCTTTGACGGGTCGTACACATCGTATCAGTATTTCTGATGCGCAGCTTCTTAGCCTCAGTAATCAGGAATATACAAAGTTTATGGCATCAGCAAAACGTTCTACTGATGCAAAGAATACTGCTATGGTTCAGCGTGTAGGTCGCAACCTTGCCAATGCGGTGGAGACTTACTTACGTAATAATGGTTATGCTAATGAGATTAATAACTTCAAGTGGGAGTTTAATCTCGTTCAAGACAAGCAGGCTAACGCCTTTTGTATGCCTGGAGGTAAGATTGTTGTTTACGAAGGATTATTGCCTTACACACAGAATGAGGCAAGTTTGGCAATCGTTTTAGGTCATGAGATTGCGCATGCTGTAGCTAAGCACAGTGCTGAGCAGATTACAAAGCAGATGAATCAGCAGATGGGAACCAATATATTGGGTACTGTCTTGAACTCTACTGTTGGTAGTGGAGTAGGCGATATCGCTTCACAGGTAGCGGGAGGATACTTCTCTTTCCGTAACTTGAAGTACAGTCGTGATAATGAAAGTGAAGCTGACTACATGGGATTTATCTTTGCTGCGATGGCTGGGTATGATCCTGCAAATGCCGTAACATTCTGGCAACGAATGGCTGCAGCAACGAATAGCAATCGTTCTGAGATTCTGAGCGACCACCCTTCTGATGCTCGTCGTATTGAGAATATCAAGAAGTGGCTGCCAGAAGCAGAGAAATATTATCGTGGTCGTGGCTCTAATCGTGTCTCTTCTGCGGGATATTCACAGTCGTCTGGGACGTTACATATAGGCGGTTCTTCGTCTTCTAAACGCTCAAATAGGCGTTGATAAAGTTGATTAACTATCATTTATGATATCTTCTTACGGCTATTTGCTTTTTCAAGAGCGAAAGCAAATAGCCGTAATTTTTATATGATTATTACTGTTTGATAAAAAACGAAATGACATTCTTTTGTATGTGGAACTCCTCTCAAATTAACATAATCATATAAGGCTTGGAAAAATAAAACTCTTCAGACCAAATATCTGTCTTTGTTTTTTGCTTGAATAGCTTACTTTTGACGGCTGATTAACCCCATTTTTATAGTATATTATAAGCTGATGAGTACTCCGCACCATTGGTGCGAAGCACTAACACGACATGTGCTAAGCATTAACACGTCATGAGCTAAGCACGAATACGTTGGTTGGATATACAAAGATGCGAGCATAATGGTCATCATATTGAATATCAAAAGCCACTAACGGCTAACTTATACGAAATGTTTATTAGGCGTTATGATTTGTATTATATTGTCATCTTGTAAAGAAATACTTTTCTGATAGTTGGTGAGTAGCTGTTAAAGTGTTATTTTTTTTGTGAAAGATTTGATGGAATCATCTTTTATTATTATCTTTACAAACGAAATTAAACCTTTAAAGCTATGATGGATTATCTGATACAAAACCTGTGGTTAACATGGTTATTAGTAGGTCTTGTTTGTCTGATTTTAGAGATGATGAACGGAGATTTCTACATTATGTGTTTTGCAATAGGCAGTTTCTGTGCTTCACTTGCTTCTGCATTTACGGATAGCATAGTTGTTCACGTGATAGTCTTTGTCATTTTCTCGGTATTGAGTATATTCTTAGTACGACCGATTGCACTTAAATATCTTCATCAAGGTGCAGATAACAGACTTAGCAATGCTGATGCGTTGATTGGTCGTGAGGGAAAGGTAACAGATACGATTGAGGCTGGTGGATACGGCAGAGTAAAGGTAGACGGTGACTCATGGAAGGCACAGTCTGTTGATGGAATGGAAATCGATTCGGGTGCTGCTGTGCGTATTTTACGACTTGACTCTATTATCGCAACGGTCGAACGTTGTTAAACAGTAATCTGAAAATAATTAAATAACAAATAATAACCTTCGGTTTCTTGCCCCATTAAGATAACAAAATACTTAGGGTGAGGAATTAAAAACTTTAATGCTTATGGATATAATAGCTTATGTGCTGATTGCATTTGTTGTGTTAGCACTCGTTTTTGCTAAGATGTCAATCGTGATTATCTCACAGAGTGAGACAAAGATTATCGAACGTCTTGGTAAGTATTACGCAACCCTTCAACCGGGTATCAACATCATTATTCCTTTCATTGATCATGCAAAGGATATTGTGGCATTGCGTGCTGGACGTTATACCTATACAAACTCAATTGACTTGCGTGAGCAGGTGTACGACTTTGATCGCCAGAATGTGATTACAAAGGATAATATTCAGATGCAGATAAATGCACTGCTTTATTTCCAAATCATCGATCCATTTAAGGCTGTGTATGAGATTAATAACTTGCCAAATGCTATTGAGAAGTTGACACAGACTACACTTCGTAATATCATTGGTGAGATGGAACTTGACCAAACACTGACTTCTCGTGATACGATTAATACTAAATTGCGTGCCGTTCTTGATGATGCTACAAATAAGTGGGGTATCAAGGTTAATCGCGTTGAGCTTCAGGATATTACTCCTCCAGCAAGTGTTTCTGAAGCAATGGAGAAGCAGATGCAAGCAGAACGTAATAAGCGTGCAACAATTCTTACCAGTGAAGGACAAAAGCAGTCGGCTATCCTCCAGTCTGAAGGTGAGAAGCAGGCAGCCATTAACCGTGCTGAAGCTAACAAGCAGCAACAGATTCTCATTGCAGAAGGTGAGGCACAAGCTCGCATTCGTAAGGCTGAGGCTGAGGCTATTGCCATTCAGAAGATTACAGATGCTGTTGGTCAGAGTACGAATCCAGCAAACTATCTTATTGCACAGAAGTACATTCAGATGCTTACAGAACTCGCACAGAATAACAATCAGAAGACTGTTTATCTCCCATTTGAGGCAAGTAATCTCATGGGTTCTATCGGTGGAATTAAGGATATGTTTAAGTAAGGCTTCTTTTAAGCATCGCTTTTGCTGCGAATAATTAAATATAAACACTAAAATAGATGACTACTCCGTAAGCTTCTCTTGCTATAAAGGAACTTACGGAGTGGGTCTTTGAAGAAATGAAAAAACTTTGTATCTTTTGTGGTGCACGTCCTAACTTTATAAAGGTAGCACCAATCATCAGGGTAATCAATAGACTTTCTGAGGAGAATAGTTCTCATAAGGTTTCTTATTCATTGGTTTATGCAGGTAGTGAGAATGATCCTACACTCGAAGATCAGCTCTTTGATAATCTCTCTATTCGCAGGCCAGATGTTTATCTTGGTGTTGAATGTGAGAACTTGAATGAACTTACAGGTCAGGTGATGTCTAAGTTTGAGAAGTATCTACAAGAGAATCCATCTGATGTGGTTATCGTTGTGGACGATCTTGCTTCTACAATGGCGGCTGCTATTGTGACAAAGAAGCAGGCAATCACCCTTGCGCATATTGCAGCTGGTACTCGTTCATTTGATATAACGATGCCTAAGGAAATCAATCGCTTGGTAATTGACGGTCTTTCTGATATACTTTTTACAGCCGGATTTAGCAACAATAGCATTGCTAACAAGGAAGGAGCAGAGTTGTCAAAGGTTTATATGGTGGGTAATATTCTCATTGATAATATCCGCTATGACCGTGAGCGTATTGAGGGTATGAGGCTTTCGGATATTGACGAGTTGGCAGGTTTACCTTTGAAAGAGGGTAACTATCTTGTCTTTACATTGAACCGTAAGGCGTTGTTGGCTGATCAAGACAATCTTGAACGAATGTTACACGTGTTGAGTGAGACAGCAGGTGATACCCCTATCATTGCTCCTCTACGCGACTCAGCAGTGCAGGTTATCATGGCACTTAGCTTGAAGAAGAACATCAAACTCCATAACCTCCATATCGTAAAACCATTGGGTTATCTTGAATTTGCTTATCTTACAGCTCATGCTAAGGGTATCATTACTGACTCAGGTAATGTTGCAGAGGAGGCAACATTCAATGGTGTACCATGTATTACGCTTAATAGCTATACTGAACACATTGAAACTGCAAAGGTAGGTTCAAACGTTTTGGTTGGTGAAGACCCAGAACTGCTCCGTTCTTCATTGAGCGATATGGTTGCAGGAACATGGAAGAAGTGTGGTGTACCTGAGCGTTGGGATGGCCGTTCAGCTGAACGTGTTGTTCAAATCCTACTCGAACGTCATTAATTCGCATTTATATTGAGAGTGGCTTTAACGCTCTTAATGTAGGGACAGATATTCTTGTTGTTCGCTATTATTATAGAATAGTCGGACAATAGAGGATATCTGTCCTTATTGTTTCTATAGGATAAAAGTGCAAAAGACTAAATGTTGCTTTTATGTATGCAGTATTAAGTAATTAGGTTAGTAAGAGATTGCGCGGTAATTAGTGCTTAGCACTATTGGTGTTTACCACCAGCACGATATGTGCGGAGTACTAACACGTCGGCTGAGGGTGGGAGGGTAGGGATGTTACGGTTATCATTACAAATATAGTATGACGTTAATGTTTGTCTAATATTGTAATTGTTTGCCAGACAGATGTATTTCTTAATCCATGAATCTTTCCTTGCCAGTAATCATAATTATGATTTGTGAATTATAAATTATGAATTAAAGAAGTAATCATAATTATGGATTTTAGATTTTGAATTCTGAATTATTTAGTACCTTTGCATGAGTCTTTTAAATGGCAAAAGTTTATGCATGGACATACAGATAATTATACCTTCCTAACGCAAGCACCAGTTCATCGAGTCATTGTCACGATGGCTATACCGACTATTATCTCAATGCTTGTGACGGGATTATATAATATTGCCGACACGTTCTTTGTTGGTAAGATTGATACACAAGCAACTGCAGCAGTGGGAATAGTGTTCTCTCTAATGTTTTTTGTGCAAGCAATGGGCTTTTTCTTTGGGCATGGTTCGGGCAATTATATCTCTCGTGAGTTGGGCGCACGTCGCCATGAGAACGCTGTGAAAATGGCTTCAACAGGTTTTTTTAGCTCGTTCTTTTTCGGATTAGTTATCCTTATTCTTGGCGAGATATTCCTCACTCCACTTTCCTTGATGCTTGGTAGTACAGCTACCATCCTTCCTTACACAGAAGACTATATGCAAGTCATCCTACTTGGCGCACCTTTCTTGACCTCATCACTTACCTTGAACAACCAGATGCGATTGCAGGGAAACGCCAAGTTTGCTATGTTTGGAATCGTTACGGGAGCTATGTTAAACGTAATTCTTGACCCAATCCTCATCTTTACTTGCGGTTTGGGTGTTAGCGGTGCTGCGTGGGCAACAGTGATAGGACAGGCTGTGTCCTTCGTTATTCTTTTCTTAATGACGCGCAGAGGAGAGAATATAGCCATTCATTTTCGTAATTTCTCACCCTCATTACAGCGTTATAAGGAGATATTCTATGGTGGCAGTCCTTCCATGATGAGGCAGGGATTGGCTTGTATTGCCACAATGTCCTTAAACTTAGCAGCAGGTGTTTATGGCGATTCGGCTATTGCAGCGATGAGTATTGTTGGGCGTATTGCCATGCTTTCCTTTGCTGTTGTCATCGGATTGGGACAAGGATTTCAGCCAGTCTGTGGCTTCTGCTATGGTGCAGGCTTATATGACAGGTTGAAGGAAGCCTATAAGTTTACTGTAACTATTGGTACGATTTTTCTTATCGTGTTAGCTATTATTGGCTGGATGATAAGCGGAACGTTGATAGGTGTCTTCCGTGATGACCCCGAGGTGATTGCTATTGGTGTTGTAGCCTTGCGATGGCAGCTTTGTGTTTTTCCTGTTAATGCTCTTATTTTGGCAAGCAATATGCTTGCTCAGACCTGCCGTAAGCCGTGGCGTGCGAACTTTTTGGCAGCAGCCCGACAAGGTTTGTTCTTTATTCCGCTGATATTTATTCTTCCATCTTATTTTGGGCTGTTAGGTGTTGAGATGTGCCAAGCCGTCAGTGACGTACTCTCTTTCACGCTTACAGTACCTATTGTTATTTATACCTTCCGTGAGTTTACACGTGAAGCAGCAGCAAAGAAAACAACAGTATGAGTACACTTTATATTAAGAATATGGTTTGTGATCGCTGTAAAATGGCTGTTAGCCAAACTTTGCAGCAGGTCGGACTACACCCCCAAAAAGTTGAATTAGGTGAGGTTAGTATTGAGGAAGACCCTTCTTCTGTCCAACTTTCTACCCTTCGGACAGCCCTTAAAGAGCTTGGTTTCGAACTTCTTGACGATCGTCGTCAGCAAACCATCGATCACATCAAGTCTGCTTTAATCAGACTTGTACATTACCATGATAATCAAAGTTCAACTAATCTTAGTGATTATCTGTCATCTGAACTTCGTCAAGACTATAGTGCGCTTTCAAAACTCTTCTCTGAGGTCGAAGGAAAGACTATCGAAAGATATTATATTGAGTTGCGTATAGAGCGAGTGAAAGAGTTCATTCGTTATGATGAGTTGACTTTGACGCAGATAGCGCTTCGTATGAATTACTCTTCTGTGGCTTATCTTTCCAGCCAGTTTAAGTCTGTAACTGGCATGACTCCCAGTCAGTTCAAGGGAATGAAAGATAATCTTCGAACACCTTTGGATAAACTTTAGACTGCTATTTACAATGTTAAGTCTACTGCTTATAGGTGGAATATAATTTTTGTTCTTACTGTCGGGATGGAAAATAGACAGATGTTAGGAGGAGAGTGAGCATATGTTTAATGATGCAAAGAAGAATGTTTTGTTGTAATATTTTACTTGTCATATTTTAATAAAGCACTAATAGCGTTTCAATTGGGCCTTAATTGGCTTCTTAAAGACGCCCTTTAGGAAGCGAACTAACGCCCTTTTGCACTCGTGTTAAGCACCTTTTGAAATGCGATTTTGTAACTAATTGATTTGCTGTTGGTTATAAACTCGACTTTTATATCTATCTTTTAGCATTATTCTAAGGCTTTAGTTCGAAATTATGTAATAATTTTTCAACATCTGGATAATGATATTTCAGACTCTTTTCTTACCATGTTATGAATGAACCTCTTGTAGAACCGATGCGAGAAGTTATAATCTTTATCCATAATTCTATAAGACATGATAGATAATATATGTGTAACTTTGCAAACGATAAGAAGAAAATAGAATAGTAATCACATAATATTAATAGAAAGGAAAGACTTATGAAAAAGAATGTTTATGCAGTAAGTGGTATGAAGTGTGTACATTGTAAGGCAAATGTTGAGAATGCCTTAAAAGCACTCAATGGTGTAGTGTCTGCTGAAGCTAATCTTGAAGATGCTAATGTCACAGTAGAATATGACGAAAGTAAGGTTAATCCTTCTGAAATCAAGGAAGCTGTAGACAATAGCGGACGCTATGAGTTGAGTTTGTAACAGCTTATTTATACTCTAAAGAGCATATTTTATGCTCTTTTCATTTGTAGAATCCTTCCCCTTCGTTGGTAAGGGGAAGATAAAAATAGTATCATTATGAAACAGACAATTCCAGTTATAGGTATGGCTTGTTCCTCCTGTTCAGCCAATATAGAGAAGAAGTTGAATACACTCAAGGGTGTTAATTCTGCTTCTGTTTCGCTACCTGGTCGTTCAGCCTTGATTGATTTCAATCCTCAGGTAATCTCACTTGAGAAGATGAAGGCTGAAATCAATGCACTCGGATATGACTTAGTGATAGATAAGGAGACGTCGGTAGACGAGATAGAGAAGCGTGAGTATGTACTCCTAAAGCGTAAGACAGTGTTGTCATGGTTGTTCTCAATCGCTGTGATGTGTGTGTCTATGCGATGGATAGACTTGGGTTCTCGTGATATTACCAATCAGGTTGCATTATTGATAGCTTTGGCAAATATGCTTTATTGCGGTCGCCAGTTCTATGTATCTTCGTTTAGACAGTTGCGTCATGGCAGTGCAAACATGGATACATTGGTGGCTTTGTCTACGGGTATTGCCTTTCTTTTCAGTGCGTTTAACACGTTTTGGGGAGATGCAGTATGGGCAAGTAGGGGAGTTGTATGGCACACCTACTTTGATGCTTCAGTAATGATTATTACCTTCGTTTTGACTGGTAGACTGTTAGAAGAGAAGGCTAAAGACGGTACGGCATCTTCTATTCGTCAGATGATGGGTATGGCTCCGAAGACAGCACATATCGTTGATGGCGACAAGATAGAGGAGGTTCCACTCTCAACCATTGAGGTTGGGGATGTTTTGGAGGTTCGTCCTGGTGAAAAGGTACCTGTAGATGGTGAGGTGATTTGGGCAGAAAGCTTTATGACAGCTGATGCAGCCTACGTTGATGAGAGTATGATAACGGGTGAACCAACGCCTGCGGAGAAGAAAAAAGGCTCAAAGGTGTTGGCAGGAACAATACCAAGTCAAGGTAAGTTCCGTATGCGTGCTCGTCAAGTTGGTGAGGACACAGCCTTAGCTCACATAATTAAAATGGTGCAAGAAGCACAAGGTTCAAAGGCTCCAGTCCAACGAATCGTTGATAAGGCAGCCTTAGTATTTGTACCAGTGGTAGCTTGTATTGCTCTTGTTACCTTCCTTTTATGGTGGTTGATAGGTGGGAATAGTGCTTTACCACAGGCAATCATGTCGGCTGTAGCCGTCTTAGTCATTGCTTGTCCATGTGCAATGGGATTGGCAACACCTACTGCGCTTATGGTTGGTATTGGTAAAGCTGCTCAGAAGCAAATCCTTATTAAGGATGCTGCAGCCTTAGAGAGTCTGCGTAAGGTAGATGTGTTGGTGACCGATAAGACTGGTACTTTGACCATACCTAATAAGAACATCGACTTTACAAAGGCTGATAACCTTCCTTTTGAAGAGCGTGAAACATTAAAGCCTAATGCTCGTGAGGCAATGGATGAGCTGCAGAAGAAGGGGATTGAGGTCTATATGATGAGTGGAGATAAGGACGAGGCGGCTCGTTATTGGGCTGAAAAGGCTGGTATAAAACACTATCATAGTAAGGTGTTACCACAAGATAAGGAGAATCTTGTTAGACAGCTGCAAGCCGAAGGGAAGCGAGTAGCAATGGTTGGTGACGGTATTAACGATACACAAGCCTTGGCTTTGGCAGATGTAAGTATTGCTATTGGTAAGGGAACGGACGTAGCTATGGATGTAGCACAGGTGACACTCATGGGAGATGATTTGTCTGCTATCCCAGAAGCGATACAGTTGAGTCGCAATACAGTACGTATGATTTGGGAGAATCTCTTCTGGGCTTTCATCTATAACATTGTTTGTATCCCATTAGCAGCAGGTTTGCTTTATGCTTTTGGCATTGATTGGCAGATTACTCCATCGTTGGCAAGTGCGCTGATGGCATTCTCCAGTGTTAGTGTTGTACTTAACAGTCTTCGCTTACGGTGGATGAAATAGGATGAATTTAGTATTATAAAAAATAGAGTTTACTAATTACTCGTTCAGCAATGTGCTGTAGTAATTGTAAACTCTATTTTCTTATGTAAACCTGTTGACTGTTTATCTTACAGGATAATCGTATCGATTATTATTATAGAAACCATTACGTTGCGAAGGGAGGCGGTCAAACTCTACGCTAACAGAAATTGAATTCTGATTGTTTGAGCCCCATTGATAGGTCACACCACCACCAATTCTATCCATGTAGCGACTAACTCCGGTACCATAAGCCCAAGCCATTGGTCCATATCCGTATCCCATTGAAGCATAACCATAGCCGAAAGGTGAATAGCCAAAGCCACCATAGCCAGCCCAATAAGGTGAACCATAACCTCCGTAGCCAAAGGCATCTCCGAAGTTGTTAGATGTAAAAGCTTTCTGCACGAAGGCGTATGCACTCCAATGTTCATTGAACTGATATCCAAAGACAGCATTGATACCACCCACGAAGTAGTTATCACCACGATAGGTAAGATGGTTTACATATCCACCCACAGCCAATGTAGCCTTCTTTGATAGGTTCGTTACATACATTAATGACACATCCTGTGAGAAACCTGCACCATGATTGCTACCGTGACCAAAGCTTGCAAAGGCCGATGCACCAAGGTTGATGTTCAACCCCTTATGTAATCTCCATGCTCCAACACCATAACCCCAAGCCGGATAATAGAAATCATTGGGTGTAACGGTTTGTCCGTTCTCAGTAATGAGAGGTAGATTGTTGTCTATTTGTGCCTGTTGTGCACGGTCTTCAGCCAATCGTCTGGCATACTCCTTCTCAGCCTCTGTGGCTTCGCGTGGTCCTTGCAGACGTGCTGACTCTATAGGTTCCACAGTGGAAGTACTTCCATTGTGGTCTCCTTTTGTATTCTGTGCATACAATGGTATACAGAGAATAGCCGCTATTATGAAACTATATTTCCTCATTTACTTGCAAATATAAATATTTGGCAGTCAACTGCCAAGGATTTTAAAGATAATTAGTGCTTTTTCAAACTGGGGATATAAATACTCGAGTAATCCAGAAGTTCTTAATCCTTATAGTTTTATTTGGTGCGCATTATCAATGGAGGATCAGTCGTAAAGAAGAATACCGTTGCCCCATGGAACACCTGTCCAGGATACAATTCGTTACTTACTTTATCCATACCACTATTATATCCAGCATGTATTGGCTGTAATGAGATACCGCAACTCTCCTTACCATATGTGTTAATATTGAGTGTTGGTTCACTTGAGTAGACTGTCATAGCACGTCCACTCTGTGCATCAAAGAGGATTGCTGCAGCCTTCTGCATGTTATCAGGATGTCGCAACTGATAGGCATTGTCGTATCCCTTACTCGTACTCTTGATACGCTCACCAATTTCTCTTGGTTTGGTAAAGTCGAATGGAGTGTTTTTTATACGTTGAAGCACACCTGTCAACTGTCTTTTAATGTTGTAGGTGTTTATCTGAACAGCATCAATCCAGAGATGTTGTTTGAGGATAGAGCGGTGCATCTCTCCTGACAAGTTGAAGCAAATACCATTTGTTACTTCCAATTTGGTTTCGGCTGTCGTTGCAATACGATAGTCTACATCAAGGGCGTTTTGGTCAGATAGGGTGTAAGTAACTGTGGCGTTTAACTTTCCATCTAATCCATTCTCTCCTTGTGAAGTCACATATCGTAGTGTAACTGATTGGTTGTCAGAACTAACAAGTTCCCATGTCTTTCCAGACAGTGTCTCCTCATTATTTTTACCAAAGTAGATGAGCGTAGCACCTAAAGTCCGATCTTTCAAATACTCCTCCTTATTGGTATATCCTTTTACGACAGGCTCTAACCTACCATTCCAGTTGTGGGCAGTAAGTGAGACAAGGCGAGCACCATAGTTACTGATAACTGCCTCCATACCATTTCCGTTCACAAGTCGGATTTGTACCTGCTCTTGTGCGTGTGAACAGAGAACAACGCTAAGCATTGCTACTGTCAGTATTGCATATAACTGCTTCATAGGTTTCTTTATATGTTTATGCAAAGATAGTACCAGCGAGTGCAATGAAAGTTTTACTTTTGTATTGCCGAGTGCAGTCTATCTTATGCAAAGATAGTAAAAAAGATGATATGTGACTCAGAATTTCTTTATTTTAATAGAAGAGTATAACGTATTTTAGTGATAGAATTCATCGTATGAGTTAGCAGTTAGCGTTTTTCGGTCTTTAATTGGGTCAGTCCTAAAACCCAGTTGCAAGTCTACCCTCTTAAGCACATAATTTCATAAGTATTTATTAACCTGAACTCGGGATAAGAAAAGTCTGTAAAAAGTTGGTAATCTCATTATATTTTTGTAACTTTATAGTTGAAAATCAATCAATTACAATAAACATAACGATGATTACCAAGGACAAAATTACTGAAATTTTCTGTATTGCAGATGATTTCTGCAAAGAGTTTGAGTTAGAAACTGATAAAATAGGTCTCTCAGAAAAGAATAAAGGATGTCATCGCCATCGCAGGTGGCGTATGAGTAAGTCTGAAATCATAACGATTTTAATTTGCTTCCACTTTAATTCCTATCGTAATTTTCGTCACTATTATACCTTTTTCGTTAAAGAGCATTTAGCAGATTTATTTCCAAATCAATTGTCTTATAATCGTTTTCTTGAATTAGAGGCAAGAGTCTCTGTAGAGATGATGATGTTCCTGCAGATATGTTGTTTTGGGAGGTGTACTGGTATTAGTTTTATTGACTCAACTTGTATTCCAGTTTGCCATAATAAACGTATTTGTCGCAATAAGGTTTTTAGAAATTATGCAGTAAGAGGGAAAAGTACAATGGGATGGTATTTTGGATTCAAACTACATCTTATCTGTAATGAAAGAGGTGAGATTCTAAACTTTATGCTCACTAAAGCAAATGTTGATGACCGAGACAAAAATGTATTTAATAGGTTGACAGACAAAGTGTTTGGTAAATTATTTGCAGACAAAGGGTACATTTCTCAAGGATTATTTGAGCGATTGTTCAATGATGGAATAAATTTAGTTACTGGCATTAGGAGTAACATGAAAAATAAACTGATGCCACTTTATGATAGACTTCTTTTAAGGAAAAAATCTGTAATAGAGACTATCAATGATGAGCTAAAGAATGTAGCTCAATTAGTGCATTCAAGGCATAGAAGCATATTTAATTTCGCAATGAATGTTCTCTCTGCTATTGCAGCCTACAGCTTCTTTGAGAAGAAGCCAGCAGTGAACATAGACTTTGCTATAGAGCAACATTCGGGACAGCTTACATTATTCTAAAGTAATCTGTTTTATTATTATCTTTAGGCTCAATCAAAAGATTGAGTCTAAAGAGCCGTTGTACTAAACCAAACAGAAGAGTGGGATGATACTTATCCCGAGTTCAGGTTATTACCTTTGCATCATGAAGAGTCACCAATTATTACGTTGCATCTTTCCAGATGTACTTGCCGACTACTTTGATGTTGTCGATATTCACGAGAGTGTTTCGCAGTTTGACTTTTGGCTTGACGAGCGTAACTTTATGGAAAAGTCAGACCATAAGTTAGGCACTGTAAGCAGTTATGGTTTTACCAGCGAGCGTGTAATTCAGGACTTCCCCCTTCGTGGCAAAGCAGTTTACCTCCATGTTCGCCGTCGCAAGTGGCGTGACAGTTCCAACGGAGAGATATTTACTTATTCATATGATGACTTGACGGCCGAGGGCAGTAAACTATCCCCCGAGTTCGTTTCTTTTTTAAAAGAATAGAATTGAGTCCACTGCAGAGAGCATCGCAAGTATCGGTGCGCACTATGGCGTAAATGGTAAGCTGTTATCCACACAGTACAAGGAATATTTCAGTGATTACCGTAGCTGGGATCAGTTGGATCATGCTCAAGACTGGCTATTGTTTGAAGATAACATAGGTGAGAGTCTAAGTATTGATGAGACCTGTCTAAGCAGTGGCGAGGTTTATACTTTTCTGACCAACAAGGCGGGAAAGGGAAGAAAAGGGACTTTGGTAGCTGTGGTTAAAGGGACCAAAGCAGAGGATGTTATTCAGGTTCTCAAGAAGATAAACCTTTCTAAACGGAAGACAGTCAAGGAGATAACACTCGACTTGTCATCTTCTATGATGCGCATAGCCCGTGCCGTTTTTCCCAAAGCACTTATTACCAATGACAGATTTCATGTGCAGAAACTATATTATGATGCCCTGGATGATATGCGTATCGCTTACCGGTGGACGGCAAGAGATAAAGAAAATGAGGAGATAAAAGAAGCTAAATGTAAGGGAAAGGAATATATACCATTTAGATACAGCAATGGTGACACGCGTAAGCAGTTGCTCGCCAGAGCAAAGATCATATTGACCAAGCACAAGACCAAGTGGACTGAAACACAGAAAGGTAGGGCACAAATCATCTTTGAACATTATCCGACACTGAAAAGGCATATGATTTGGCTATGAAACTTACCGATATTTATAACATCAAGAGCATCAAGGATGCTGCAAGGCTGAAGCTGGCTAAATGGTTTAATGAGGTTGAAGAGCTGGGAGTGGACAATTTCTACACAGTGATTGACACGTTTGAAAATCATTATCAAACCATACTCAATTTCTTTGTAAACAGAGCTACGAATGCAAATGCCGAGTCATTCAATGCTAAAGTTAAGGCATTCAGGGCATAGTTCAGAGGAGTCACAGATTTTCCTTTCTTTTTATATTATTGCTGTCTGGTAAAAACAAACTGAAAGCTCTGTATCTTTTTACTCATCGGTGTTGCAGCCGTTTTACTTATCCAGGGGGCTTGGTTTTCAGTTTCAAACTGTAAGCATTATAAAATGTGCTTATATTGACAAGGAGAGCCCTATAATAACCAGATAAATTAATGAAATCATAAGTTTAAGTCTATTTTAACTAACACAGATAACTCCAAAAAAGTTTTATCGGACACCAATATTTTTATATAGACTTCACTAGTGTCCACTAAAAGTGGTCCTAGTCAAAATTAAACAATAGCAGTTCATTTGAACTAATTCGTTCTTTGTCATTATTGAATATAGTTTTGTCAAAAGGTTCTCTCAAAGGAGTCTTGTCTGTTAATGAGATACTAAGTATCTGTAATACTTCATAAGTACTCCTTTCGAGTCTCATGTCATGTTGGATAATAGCTACCAGACAATAAGCCGATATTGCTGAATAGATTTGTGTCCTAACGGCGTTTTCTGTTGTCCCCCAGAATTTCTTAACCTTGAGATGCTGCTTGAGCCATTTGAAGAAAAGTTCGACTTACCACCTATTTTTATATAGGTTTGCAATCTGCAGTGCTGAGAGATGTTTAGCATTAGTCAGATAAGTAAACTCTCTGTTCAACTCTTCATCCCAGTACTGGCTAAGCCTGAGAGATTCAGGATAGTATTGGTGAGGATAATATCCTGTCAATTTGATTTCAGCATCCGAGAGTATATTTTTGGGGAAGTCTACGGCTCCATTTAACACACTTCTACTGGAGATTCTTCTTGGACCTGACCACAAAGAAAGAATCTAATGTCTTGATTCTATAGAGTCGTTTAAAGTCATTATAACCTCGATCAAAAACATAGTATGAGCCTATTTCATAAGGGATTACGTCCATTGCATTGACATCATTCACTTTAGCACTCGTGATATGGAAGAATGTTGGTATTTGAGTCTCAATGTCGTAGAGAGTATGTATTTTAATACCACCCTTATGTTTGCGAAACTTTGCCCACCAGAATACGTCCAGACACAAATCTATTGTCTTAGAGTCGAATGCATAGATATTGCCAGCTAGCTTAAAGATGTCAACGGCGCACTTACGCCTAGCTTCATCAACAAGAAAATAAGCAAAATCCTCAGAGATGCGATAGTCTCGATTCTGATTTGCTTTGGCAAGATTACTCTTTGTCACATGTTTGCCAAATCCTAGGTGATAACTTTTCTTTTGGTGAGCATTGATAGCGACTATTAGATCACGAAGACTTTCTCGATTACTAAGTTGACCAAATATGAGGGTAAGCAACTGATTCCAGCAACTAAAGAACTTCACATACTTATCACCTCCGTATTTACGTACGAGATAATTGAAGTGATTTCTGTCAAGAAATGAGACTAACTGAGCGAAAACGTATTTGTCTTTATACATATGCAGAATCTGATGATACCCTGCAAAGGTACAAATTCAAATCCGTTGACTCTGAAAACCTTTGCAACTAGCTATTTTTCAACTATTTCAAAGAATAATTACTGATTTTAAGTGGACAGCAGTGTATAGACTTATGAAATTGTGTGCTTAACCCAAGTTTAACACCCACTTTCGCCTAATTGTTACTGTCACCGTACTTTTCTCGTTTTTCTTATGGGCTCTGTGTCCTACAAATTTTATTCTTTTTGAATGGTGAGTGTTTTAAGTTCAACTTATCGTATATTTGTTTTGCTTGCTTCGAAGGACTACCACATTGGCGCATCTCGATGGTTTCACCTAATGGATTCTTCCCTTTTGTGGTGACGAGCTTTTGGGTGCTCATACGTCGTACTATCTCGGTCCAGTAACAGGATTCTCCTTCTCGTTTTAATTGACAACGGATGGTGTTTACCACCCAGTAGGCTAATAAACCGAAGAAAAGGTGTGCGTCGCTTCGCTCATCTTTCTGATGATAGATAGGACGGAGGTTGAGATCATTCTTTAGTTGTCTGTTCGTACATTCTATTTCACGAATGAGATTGTAGTATTCCCATGTCACACGCTCAGAAAGTGTCCTGACATTGCTGCGGAGGAAATAGACTCCGTGACCAGATTCCATTGCCGAGAGGTCTTTTATCTCCCAGTCTACACGCAGCATCTCCTTGAGTATCTTCTCATTTTTTATGTAGCTTATCTGGTAGAATTTCGCTATAGAAGGGTACTTCTGTATGGCACGTCCTGTACGTTCAACAACCTTTTCATAGGTTTTTGTTCCACCTTTCTTGGAGATTCCATCGTTTATCCTCTGCAGTTCCATCTCAAAACGCTCTTTCCAAACCCTGTTCATGGACGACTCTGTCATAGCTTTCGAAGGAGATGTTATTTCGAGATAATAATCCTCATCATCCTCTGTCTTAACCTCTTTCAGCGTTATCTTCTGCCGACGGGCATCCATTACCGTAACACTCTTGTTATCATCACTGAGCGTATAGTCTTTCATTTTCGTACGGGATACGCAGAGATAATTGTAACCCTTTTTCTTTATTAGCTCCAAGTTCTCTTCCGTGGCAACACCTGCATCCATGACAACAAGCGTATCCTTGGTTCGTGATGGATTCCTCTTTGCCAGCGTATCAATCATATTGGGTAGAGACTTGGGATCTGCTGTATTACCCTCTAAGATAGAAGAATAACGTATAAAACCTTCTTGATTGATACATAATGCAAGTACAAGTAGCTTACAGTCAGAGCGTTTTTCTTTTGAACGACCGAACTTGGCTTTATCGCTATTACGCTTACTACCCTCGAAATAGAAGTTGGTTAAGTCGAAGAGCATCAACTTGTTGTCTATATTAAAGATATCGTCAGTAACGCTGCACAGATGACGCTCTAACTGTTCCTTTAGTTCATACAACTTGTCAGTGATTTTATACAGAGAATTGATCCCTGGTGTCCAGCCAGGAACTCCACTGTAAAGTTCGCCAGCAGCTGAGTTATCGCGCAAATAATAATAAGATGAACGTTCAGAGACTGCATATACCGTGCGAACAATCAATGCTGACAAAGCCGTGTGTATCGCATTCTCCGTCCACCCGTTTTTGCGCAGAAAACCCTCTAACTGCAGCTTGTCTATCGTCTGCTTGCAGAGCCACTCTGCACCAACATTCCTTGCGTCAGTATAGTTTGCCGTCTCGAGGTCAATGTAGTTCTCATATTTTCTCAGCGACTTCTGCTCTTCCTTATTAAACCGATCGATTCCACCTTCTTTCTCCATACGGCTCCACCATTCGTCAGCCTTTGCCTGTTCAATAGGAGTAAGTCCCTCAAGGCGTTCTTTGAAAAGCGAGGGTGTACTTCTGGTTTTGAAGCGTTCGGTAAGAGCGTATGCAATTTTTCGAACCTGTACAGCAGTAAGTGAAGGTTCAAAACCTATGTTCAACAGAATTAGCGAATGTACATGACCCTGCACGTCACGATATGACTCCTTGATGCGATAATAAGGAGCCATGTCGCCTGTGGCAGGGTTGAATCGTGTCTGTACATTTGCGTGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP054011|371322:417444|413649_413874_+|WP_172891340.1|transposase|DBSCAN-SWA
MKLTDIYNIKSIKDAARLKLAKWFNEVEELGVDNFYTVIDTFENHYQTILNFFVNRATNANAESFNAKVKAFRA
>NZ_CP054011|371322:417444|401720_402668_+|WP_013263822.1|DBSCAN-SWA
MDIIAYVLIAFVVLALVFAKMSIVIISQSETKIIERLGKYYATLQPGINIIIPFIDHAKDIVALRAGRYTYTNSIDLREQVYDFDRQNVITKDNIQMQINALLYFQIIDPFKAVYEINNLPNAIEKLTQTTLRNIIGEMELDQTLTSRDTINTKLRAVLDDATNKWGIKVNRVELQDITPPASVSEAMEKQMQAERNKRATILTSEGQKQSAILQSEGEKQAAINRAEANKQQQILIAEGEAQARIRKAEAEAIAIQKITDAVGQSTNPANYLIAQKYIQMLTELAQNNNQKTVYLPFEASNLMGSIGGIKDMFK
>NZ_CP054011|371322:417444|392015_392945_-|WP_004360522.1|DBSCAN-SWA
MEKEKKSEGMMSVIAALGANILVAISKFVGFAVSGSAAMLNESIHSIVDCGNEILLLVGNRQSTAKISDKHPFGQARAKYFYSLVVAMMLFFAGGALGIMEAAEKLFHPEHSLENTWLVIGILAFGLLVETVSLRVAFKEIKELNKDNLSLYRFLRESRHSEILIIFAEDSCAVVGLLIALGGTLLTHLTGNPFYDALSGVLIGVLLCAAALFLSREFYSLLIGESVTQKDLTRIKETFNRTEIDRLINVKTIHLGPTDILVTAKIDIKSEYEAQVPQLVNDIEKNMRAAFPDYKIYIYIETDKYKEDY
>NZ_CP054011|371322:417444|373248_374109_-|WP_004360511.1|DBSCAN-SWA
MTLLQTIIISIVEGMTEFLPVSSTGHMIITQNLLGVPSGDEFVHAFTFIIQFGAILSVVCLYWKRFFQIDHTPVPVDETCTFKKIIHPIRFYWLLFIGVLPAVIIGLAAKKSGLLDWLLDSVWVVAIMLVVGGIFMLYCDKLFNKGKEENQVTEKRAFSIGLFQCLSVIPGTSRSMATIVGGMANGLTRKRAAEFSFFLAVPTMAGATLLDLLDLLKGDSTWASAHNLIMLAVGCVVSFIVALLAMKWFVSFLAKYGFKWFGWYRIIVGVIIIIMLLCDIPLNMVD
>NZ_CP054011|371322:417444|409246_410116_-|WP_036886422.1|DBSCAN-SWA
MRKYSFIIAAILCIPLYAQNTKGDHNGSTSTVEPIESARLQGPREATEAEKEYARRLAEDRAQQAQIDNNLPLITENGQTVTPNDFYYPAWGYGVGAWRLHKGLNINLGASAFASFGHGSNHGAGFSQDVSLMYVTNLSKKATLAVGGYVNHLTYRGDNYFVGGINAVFGYQFNEHWSAYAFVQKAFTSNNFGDAFGYGGYGSPYWAGYGGFGYSPFGYGYASMGYGYGPMAWAYGTGVSRYMDRIGGGVTYQWGSNNQNSISVSVEFDRLPSQRNGFYNNNRYDYPVR
>NZ_CP054011|371322:417444|415563_417444_-|WP_172891341.1|transposase|DBSCAN-SWA
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKTRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYSGVPGWTPGINSLYKITDKLYELKEQLERHLCSVTDDIFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINQEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVVMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDEDYYLEITSPSKAMTESSMNRVWKERFEMELQRINDGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKILKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNDLNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGETIEMRQCGSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054011|371322:417444|382960_384508_+|WP_036886408.1|DBSCAN-SWA
MKKIIMLSICGCLLSSCSLDLQPENGLTYSNSFNKEKELNATTTSILYYINTVVGNNYVLSTAGMKADEILDGKQLREWNPRTVIKSEYSWKGLYDIIFESNLLLDNIDKTKGLAEDRRKYHVGQAEFALGLSYFLLAQRYGEAIITDNSSEIKPYSLSSQSDVLNAAIEHAKKALDILPTWDKLTDLNGVSITNRQTASKGTAAALLAQIYAWKGSVTELYKLQGNAQEDYQKSIDYSTQVIDGQVGNYQLCSSPEELCTYLSNEKSPNPEAIFSLYFDKTRSENVVSPNEVAQNFVSWPVREDQTLADLPSSSTYQLYTSTIERLFPDATDQRLQAFFYQWGTSHEVDGTDYAIMYKFRKAIMDADQYSASGKTYRTVDADYVYWRLADFYLLRAECYQKLGNEAKAIADLNVIRSRAGALSYPSTYDTEGLKKAIFLEREKEFIGENDARYADVIRNGYVKEELQGKFRLLTNQDIQGGALFLPLPKDAWQDKDGHIINTLLRQKPYWQAYN
>NZ_CP054011|371322:417444|399671_400571_+|WP_036886418.1|DBSCAN-SWA
MKIKYFLMAAVVALMTACGTASKVPLTGRTHRISISDAQLLSLSNQEYTKFMASAKRSTDAKNTAMVQRVGRNLANAVETYLRNNGYANEINNFKWEFNLVQDKQANAFCMPGGKIVVYEGLLPYTQNEASLAIVLGHEIAHAVAKHSAEQITKQMNQQMGTNILGTVLNSTVGSGVGDIASQVAGGYFSFRNLKYSRDNESEADYMGFIFAAMAGYDPANAVTFWQRMAAATNSNRSEILSDHPSDARRIENIKKWLPEAEKYYRGRGSNRVSSAGYSQSSGTLHIGGSSSSKRSNRR
>NZ_CP054011|371322:417444|410235_411186_-|WP_004360536.1|DBSCAN-SWA
MKQLYAILTVAMLSVVLCSHAQEQVQIRLVNGNGMEAVISNYGARLVSLTAHNWNGRLEPVVKGYTNKEEYLKDRTLGATLIYFGKNNEETLSGKTWELVSSDNQSVTLRYVTSQGENGLDGKLNATVTYTLSDQNALDVDYRIATTAETKLEVTNGICFNLSGEMHRSILKQHLWIDAVQINTYNIKRQLTGVLQRIKNTPFDFTKPREIGERIKSTSKGYDNAYQLRHPDNMQKAAAILFDAQSGRAMTVYSSEPTLNINTYGKESCGISLQPIHAGYNSGMDKVSNELYPGQVFHGATVFFFTTDPPLIMRTK
>NZ_CP054011|371322:417444|404424_405789_+|WP_004360531.1|DBSCAN-SWA
MHGHTDNYTFLTQAPVHRVIVTMAIPTIISMLVTGLYNIADTFFVGKIDTQATAAVGIVFSLMFFVQAMGFFFGHGSGNYISRELGARRHENAVKMASTGFFSSFFFGLVILILGEIFLTPLSLMLGSTATILPYTEDYMQVILLGAPFLTSSLTLNNQMRLQGNAKFAMFGIVTGAMLNVILDPILIFTCGLGVSGAAWATVIGQAVSFVILFLMTRRGENIAIHFRNFSPSLQRYKEIFYGGSPSMMRQGLACIATMSLNLAAGVYGDSAIAAMSIVGRIAMLSFAVVIGLGQGFQPVCGFCYGAGLYDRLKEAYKFTVTIGTIFLIVLAIIGWMISGTLIGVFRDDPEVIAIGVVALRWQLCVFPVNALILASNMLAQTCRKPWRANFLAAARQGLFFIPLIFILPSYFGLLGVEMCQAVSDVLSFTLTVPIVIYTFREFTREAAAKKTTV
>NZ_CP054011|371322:417444|376612_377296_+|WP_004360514.1|DBSCAN-SWA
MKRIAILIVLVTSTLVSMAQNKLGTWSVIPHVGVSISSLLGGSGIYEIGIEQGIEVKTHALLGFVGGADVMYQASDAVGLSAGLSFVQAGCKLEDYTDDHTVVYDRYLRINYVSMPILVHNKLLAGFSVKVGIEPTCVFNANNHEVYQSYSVDKDGKKTNFQENTYDFDIKNGMCKFGLSIPIGVSYEYENVVLGALYHVGVFKIYKEGDSSRSSVFEVSVGYKLNL
>NZ_CP054011|371322:417444|387161_390014_+|WP_036886412.1|DBSCAN-SWA
MFKNIIKCLSSVPVALLIGFLFSPLSSANAQMNGLRKGKLANGLTYYIYNDGSATGEAQYYLYQNVGAILENDEEMGLAHVLEHLAFNTTDHFPNGVMNFLRSNNLNDFEAFTGVDDTRYAVHNVPTNDAKLNENMLWVLRDWCHGVKMTPKDIEKERGIILEEWRHRSGVDRRLTDAIAPVVYNHAGYATHNVIGSQKILETFQQKQVKQFYDKWYRPNMQFIAVIGDVDVDQMEKNIQIVFKTLPAKQASAVNSQTRQIPDNTTPLYMRFIDPENKSASFGLYQRYEVKGNAPEEDRVRQFIFTKFFNTLAPKRFVMLKNADKESYIAAEVSLSPLVRNYYQMAWDMVPYQGNEQKALQQMLAVRDNLRDQGFTAAEFNAEKEKMYNGMKDVLEAKGLGTPDNALMLFRQNFLYDIPVQDFRGQINRNLETLVELEVEDMNAWMKSLLNDNNLAFVTYSKSQSEMNITENDLMAALKAKSSFSDMARADGMKPISQLIDFPLTGGKIVSEKQLKTLQAKEWTLSNGAKVLYRNVPELSGQFLFAGSAEGGKSIVPAQELANYNAMRSLLMQSGVYNYNRNQLAQWLQGKNINLSLSLEDYSDGIGGNAPVDKADDFFSYLYLILSRQNFSKSAFDKYVQRNFYVYENRATTGMAAVQDSIQQLLYPVSAMNPRQDEAFFKSVQFDKLQEQFQAHLGDVSRFTYCLIGDIPEAKAKELVLRYIGSLKGEGKPVKTAIQPMDFSSSTPVIKRTFETETEGGMAEIEISFANKQKLSEREQAALEVMRGLLERRYFDVLREKEHLTYTVGVQSNYTSQPVAGESLNIHLSTAKENADKAVSLVYSILDDVKAGRFTADEFKAAMVPLAVDEEQSGAASQSNSDPSVWMALLNIYAETGNELSPNDNAASAPVFKTLTPQDITAVAMKVMTNAKQREIIVKPAAQEGKHTFK
>NZ_CP054011|371322:417444|398224_399538_+|WP_004360526.1|DBSCAN-SWA
MHEEQKIINGIPIVDQWRSYWLWLPTLYLTRGLPYVILLMTSLVYFNRMGLSNGSITLTTSWLILPFILRPLLGRLVVGYWSKYAWVILTEFVMALSLGGLAFMASSVDWFEWTVFFLMIIATMAALHDVAIERLYKRETVLHNRPAFIGTRAISYMLSIIVGMAIPVTIAGNLEVIYRTVAPSWATIFRVLSVLLTCLMLLHAIILPKDNIHANLPIWTGVTRQWWHDVKAAFVRHPHYVANLCFLFAFLIPEGMFFRIAPLFLIDPGSNAGLALSPQELGLVLGTVGTFSLIGGSALGANLVRRDGLKRWLWLFVIALTLPKFVFVYLSYYFVSTLSIINLCVIIEQFGAGLGLTFYVVWLAHCTKGEHSTFTYSIGTAITAFSLVMTGWFTGFLQEYVGYRLFFLLVAMLGVISFIVTYFLPVTKEIGKRKRMV
>NZ_CP054011|371322:417444|374108_374351_-|WP_004360512.1|DBSCAN-SWA
MDKRNLAFGKTNFILLAIGVAVVILGFILMSGGTSTETVFDPDIFSARHIKVAPIVTFIGFISIIGAILYQPKETKEVEE
>NZ_CP054011|371322:417444|385184_385658_+|WP_004360519.1|DBSCAN-SWA
MKKMKKGIALLCLMALTIGFMVSCSKMDVGYLRTTGASFTPDSLNAFHNVDATSERGINKLPFVSTRIQGVAGTNPINYELFGVKADNQEQAQLFMKLYKEGKISVTGGLIVVTQEATQQLANGRYRLSLKVYNQDHEVVLEDIFKVVVTDDELPVE
>NZ_CP054011|371322:417444|407224_409144_+|WP_004360534.1|DBSCAN-SWA
MKQTIPVIGMACSSCSANIEKKLNTLKGVNSASVSLPGRSALIDFNPQVISLEKMKAEINALGYDLVIDKETSVDEIEKREYVLLKRKTVLSWLFSIAVMCVSMRWIDLGSRDITNQVALLIALANMLYCGRQFYVSSFRQLRHGSANMDTLVALSTGIAFLFSAFNTFWGDAVWASRGVVWHTYFDASVMIITFVLTGRLLEEKAKDGTASSIRQMMGMAPKTAHIVDGDKIEEVPLSTIEVGDVLEVRPGEKVPVDGEVIWAESFMTADAAYVDESMITGEPTPAEKKKGSKVLAGTIPSQGKFRMRARQVGEDTALAHIIKMVQEAQGSKAPVQRIVDKAALVFVPVVACIALVTFLLWWLIGGNSALPQAIMSAVAVLVIACPCAMGLATPTALMVGIGKAAQKQILIKDAAALESLRKVDVLVTDKTGTLTIPNKNIDFTKADNLPFEERETLKPNAREAMDELQKKGIEVYMMSGDKDEAARYWAEKAGIKHYHSKVLPQDKENLVRQLQAEGKRVAMVGDGINDTQALALADVSIAIGKGTDVAMDVAQVTLMGDDLSAIPEAIQLSRNTVRMIWENLFWAFIYNIVCIPLAAGLLYAFGIDWQITPSLASALMAFSSVSVVLNSLRLRWMK
>NZ_CP054011|371322:417444|401167_401617_+|WP_004360528.1|DBSCAN-SWA
MMDYLIQNLWLTWLLVGLVCLILEMMNGDFYIMCFAIGSFCASLASAFTDSIVVHVIVFVIFSVLSIFLVRPIALKYLHQGADNRLSNADALIGREGKVTDTIEAGGYGRVKVDGDSWKAQSVDGMEIDSGAAVRILRLDSIIATVERC
>NZ_CP054011|371322:417444|390214_391447_-|WP_172891336.1|transposase|DBSCAN-SWA
MNKSTHFIGQPLYVQLLNYFNRDKILSLSQAQGGEHYIKKFDAWHHLVVMLYAVMMRLDSLREIKASLFANVNRFNHLGLKHFPCRSTLSDANKRRDSEIFGSIYMNLYEKYRHELYSDSRNCGQPKWLKNLKIIDSTTISLFSNLVFKGVGRNPKTGKKKGGIKVHTEIFANENVPSDIKFTSAASHDQFALIPERYANEELIAFDRAYINYEKFSELTQRGVIYVTKMKNNLSFERIADTDYQMTTDYGVVRVETILFHKHTKEKDIYHKARKITYQDKTKKGKIRFISLLTNDFQMSVEDIIAIYKRRWQIETLFKQIKQNFPLRYFYGESANAIKIQIWITLIANLLITLVKNKIKRPWSFSGLATMIRILLMSYVAIQSFFEQPHRDWDRLITQVKAPPEELSLF
>NZ_CP054011|371322:417444|405785_406349_+|WP_004360532.1|DBSCAN-SWA
MSTLYIKNMVCDRCKMAVSQTLQQVGLHPQKVELGEVSIEEDPSSVQLSTLRTALKELGFELLDDRRQQTIDHIKSALIRLVHYHDNQSSTNLSDYLSSELRQDYSALSKLFSEVEGKTIERYYIELRIERVKEFIRYDELTLTQIALRMNYSSVAYLSSQFKSVTGMTPSQFKGMKDNLRTPLDKL
>NZ_CP054011|371322:417444|385823_387152_+|WP_036886410.1|DBSCAN-SWA
MKRRRYILLLVSLLMMVVQLRAQQGMEAANGIKFFKGTFSEALVKAKQENKILFVDFYAVWCVPCKKMAKTVFTQEEVGKYFNEHFISLQLDAEKGENVDIAKNYKVAAYPTVAFIAPDGKALSVNTGAMDKDELMEAAKIAAGESVSFEELYNKYKADNNDLDVQQQLLLKAPSFLQAQEGMDADKWVTRLQKLYKNYVAAKAPLKLINENDYRIILTLEGDEDKEHKQYMIDLMNDHLDDWMKKLGKAPAYYIVEANDIFAEDMAKDGNVKYKDYVEKVKNQYAKAYEVVGLTGITPYEKAKLYFDALFNLYKNKNVNGYVKAMETYFGKMENNLRSADYGKAAQNLYMAAGKSLKAKDHEVAIKWAEKALSQEDAVMDRVNYMVMIGDSYRELKNYTKAREYYNQAFAETLRLENMEMPQAMLQGAIKQKLSTLELLEK
>NZ_CP054011|371322:417444|412605_412950_+|WP_007369112.1|transposase|DBSCAN-SWA
MKSHQLLRCIFPDVLADYFDVVDIHESVSQFDFWLDERNFMEKSDHKLGTVSSYGFTSERVIQDFPLRGKAVYLHVRRRKWRDSSNGEIFTYSYDDLTAEGSKLSPEFVSFLKE
>NZ_CP054011|371322:417444|372528_373227_-|WP_004360510.1|tRNA|DBSCAN-SWA
MNFKEGVIIPIDKPYGITSFKALAHVRYLCTQANDGKVKIGHAGTLDPLATGVLILATGKMTKQIETLQTHTKEYTATLQLGATTPSYDMEHEVNETFPTEHITRELINATLPQFVGDIEQIPPTYSAVKVDGKRAFDYRRKGKDVTLKPKNIRIDEIEVLDFDTEKMQLSIRVVCGKGTYIRALARDLGRAVNSGAYLTALRRTRVGDVRVEDCVNYDQFEAWLQQQTIEK
>NZ_CP054011|371322:417444|402784_403909_+|WP_004360530.1|DBSCAN-SWA
MKKLCIFCGARPNFIKVAPIIRVINRLSEENSSHKVSYSLVYAGSENDPTLEDQLFDNLSIRRPDVYLGVECENLNELTGQVMSKFEKYLQENPSDVVIVVDDLASTMAAAIVTKKQAITLAHIAAGTRSFDITMPKEINRLVIDGLSDILFTAGFSNNSIANKEGAELSKVYMVGNILIDNIRYDRERIEGMRLSDIDELAGLPLKEGNYLVFTLNRKALLADQDNLERMLHVLSETAGDTPIIAPLRDSAVQVIMALSLKKNIKLHNLHIVKPLGYLEFAYLTAHAKGIITDSGNVAEEATFNGVPCITLNSYTEHIETAKVGSNVLVGEDPELLRSSLSDMVAGTWKKCGVPERWDGRSAERVVQILLERH
>NZ_CP054011|371322:417444|392979_393801_-|WP_004360523.1|DBSCAN-SWA
MKKDLYKDIRLLLLAIIVVSLFFSCSSVPSGIAEEITYHGEQLHRYLTIIKDVTSKAERSKDTITYYCNQKGQLIIERVGTDSLDDYTYSYAGDTIHIHKTHIKDQLDELLDGYYIVKNGLIVEANNTPGYYTYTYDNKRRLVCRDTPNTLCGRQTNILQWKGEKILPDKSLNITYRDTGEKTNYHNLYYFWMFGSGIRIPIPFITLGYMGVIPKGDISSYSFSSKDKDFNFKSQLTTEYDKEGRPTRIEEVVTTLNKNNKEENSKYVTEYIW
>NZ_CP054011|371322:417444|393946_394216_-|WP_036886439.1|DBSCAN-SWA
MEKENHIDRALAFMENLEKLGAQLQKADEQQKLMLQQMLMKSQNNETDTDEYRELEQRSKDLQAMINKWRPIYEERLKMVKEAQKAAKK
>NZ_CP054011|371322:417444|394463_398213_+|WP_172891337.1|DBSCAN-SWA
MEKKKQIDCFLPYSTTAMMESLAAQLYELGVVKNIYTLAADVLPTEALPLYTHQLQTGGLLSLATMRLIATTATADYALLYLKQGPITLGYHALERMLQVAEETGAGMVYADHYSVKVGKTVRHPVTAYQLGSIRDDFDFGSVVLLKTGYLKEYATREVEKDYQFAGWYDLRLFLSRKGELFHLNEYLYTEEEDDLRASGEKQFDYVNPRNREVQIEMEQVATAHLSAINALVDTTQYAQPDFSAEAFPVEVSVVIPVFNREKTVRDAVVSALSQKTDFPFNVIVVDNHSTDGTTEILSTLAADERLVHLIPTRTDLGIGGCWNYAINDAHCGRFAVQLDSDDLYSSENTLQTIVDAFHEQKAAMIVGSYRMCDFDLNTLPPGLISHNEWTEDNGCNNALRINGLGAPRAFFTPLVRQHQFPNTSYGEDYAMGLAFSRRFRIGRIYDELYLCRRWGGNSDAVLSIDKVNANNHYKDQLRTVEILARQKQNQDREKGLTDFFHNQLNQWKDVAKRFEELKGVQTREVGSALAQFNPARLVSTGAKIDKATLAKRPCFLCEKNRPKEQIVLPFGNDFDILVNPFPILPVHFTIPSRHHQQQAIADNYVQIHRLLRAYPQLMVFYNGPKCGASAPDHLHFQAGTSGILPLQRDWQWLYATSVPLLKLNDVEGIYEIKDYICPVLAIVSHTEKHDVELFSRLYEALPMKEDETEPMMNIVAWRSGEAFISVVFPREKHRPDCYSADGEAQCLVSPGSLDMAGLMILPRQIDFEGMTAERAKDVLQEVSLSDEAMNEVVKRLRNKAVDLAFDDWKYEPIVSVGIVSGDEIRFQLNGTYTIGNKEVTGKQIVKSKDGQILWNSTVYQELCFTPQNDDISFTLEDVTIGVDFHWERKEAQTFLGKLRFVVDGDKLWAINELPVERYLASVISSEMSATSSLELLKAHAVISRSWLLVQMRRRKAIEMGVQTASAPVKVSDEEGVVWYDSDAHTLFDVCADDHCQRYQGITKATSPHVEEAIKATRGQLLMNGKGICDARFSKCCGGVSEEYEYCWDNNHKPYLLSIVDNAPLGTAPTIDLTDEAVAREWILSSPEAFCNTKDATVLGQVLNNYDQETQDFYRWTVDFTQSELAELIRRKSGLDFGEIIDLQPLERGKSGRITRLKIVGTKLTRIIGKELEIRRTLSESHLYSSAFVVERSEIVNDIPQHFRLVGAGWGHGVGLCQIGAAVMGEKGYQYDEILHHYYQTAAIEAQYK
>NZ_CP054011|371322:417444|384549_385182_+|WP_036886436.1|DBSCAN-SWA
MKKIIYIITMCLTMGVFSSCTQYNFDDTGLANGKHDMTMWEYFKGDSYNWDSLRVMAERADLVSLFQGTSQYGKNFTFFGPTNHSIRRYLYDNHMERVSDIPVADCKKFILNSVLPNKRVMLDDFKEGVKSSDASTPIGKGGETVEMASGKQLWIYTFHESYNGVPAAGPLRIHLVSPTTTKTSDVASCNIETNTGVVHSLVYDFNLTDF
>NZ_CP054011|371322:417444|411563_412481_+|WP_172891338.1|transposase|DBSCAN-SWA
MITKDKITEIFCIADDFCKEFELETDKIGLSEKNKGCHRHRRWRMSKSEIITILICFHFNSYRNFRHYYTFFVKEHLADLFPNQLSYNRFLELEARVSVEMMMFLQICCFGRCTGISFIDSTCIPVCHNKRICRNKVFRNYAVRGKSTMGWYFGFKLHLICNERGEILNFMLTKANVDDRDKNVFNRLTDKVFGKLFADKGYISQGLFERLFNDGINLVTGIRSNMKNKLMPLYDRLLLRKKSVIETINDELKNVAQLVHSRHRSIFNFAMNVLSAIAAYSFFEKKPAVNIDFAIEQHSGQLTLF
>NZ_CP054011|371322:417444|374482_375361_-|WP_004360513.1|DBSCAN-SWA
MAKKRNKARSRHSLQVVTLCISTAMVLMLIGIVVLTGFTSRNLSSYVKENLTITMILQPDMNTEESTALCERIRTLHYINSLNFISKEQALKDGTKELGANPAEFAGENPFTGEVEVQLKANYANNDSIRNIVQQLRTYRGVSDITYPQSLVESVNQTLGKISLVLLVIAVLLTIISFSLINNTIRLSIYAHRFSIHTMKLVGGSWSFIRAPFLRRAVLEGLVSALLAIAVLGIGICLLYEKEPEITKLLSWDALIITAIVMLAFGVIIATFCAWLSVNKFLRMKAGDLYKI
>NZ_CP054011|371322:417444|379469_382955_+|WP_036886407.1|DBSCAN-SWA
MKYHQRMFRTLRRLPSLVFLTTFILMLSWSSPASAQVAGKKFSISFKDKSVAQILDFISTKGDYKINYSDDVKNDTLLLTISFEDVDELSAVENLLSHSSFVYNIDGKVIDVFKMKNATQGQYTIRGTVKDKDGLGVPFAIVQIKGTSQGVTADIDGNFSMPVEKEEGTITISSVGYDAKTLKYHAGKAMNVILTSSAIAMGEVTVVAYGKRNTREQVGAVASVKVEDLQKAPTASIENLLQGRMAGVDVTNLSGSPGGGGSRITIRGFSSLNQKGINDGSPLYVIDGIPVSSSAGDATGGINPLSGLDPSSIESVQVLKDAASASLYGSRAGNGVILITTKKGKSGRSEVSFNFSQSLSWLPSTPMQTLGKGERDIALRLAKSQRGAHYDYMTDKLIYPGSYKDSYGWDADNDGAYDYLWRNGKVLDSERRLPGIAQDSLNTFYNNRTNWWKYAFRVGKVTKADMLLAGGTDNIRYMVNAGVYDETGIMISSNFRRFSLLSNLDFNLSTKLSAFTRINLTYATQKAGADGGRVQGLTFDPKRTSTLLPGKGSTAEQVALRQLKDIDKTNSNYNVRLSVGLNYNILKGLKFSSTYSLDHYFTRVYTFTPDYLKYDKKSEVQASNIAMTNIQTENILTYNLALPSEHKLELMTGMTYNYDLLQNLSGTAKGGPTNSIKYAGEGWPSLFNDGGTVRAAQSFLTNQQEQSLLSFLGRAAYSYKKRYMAELSIRADGSSVFGKDVRWGTFPSVGLGWAFSEEHFMKKFWWLSFGKLRASWGKSGQKFQEPYLALGVMEESNIFNGSLGLIPQSMANKKLTWEESDQYDLGLDLQMLDYRLKLKLDYYYKYSSKLLMQSYLPGNVFLATNMWDNASAISNEGIEFEAQYDVIRKKNWNWSVGFNLSHNKNMLRKTYNGEDLNDKVLGRPVYGIYTFKDEGIVQKEEDIPMYLNASGKQIPLYFQSINNPLRVGGRKIKDQNYDGVIDDKDLYYAGSTLPAVYGGLNSHLEWKGLSFDVLFSYTISRKVMNMYKNSAFTFTKDFGVIMNYFHAGDFWTTSNRDAKYPSLEFADKDYVGQFDGNVDSNIENISFLRLKQLVIGYQIPKNWLKGSFIKDANVYLSGENLFLLTNYSGVDPEIINPYSGKDDGTQYPLNRKVTLGLNLKF
>NZ_CP054011|371322:417444|371322_372507_-|WP_004360509.1|tRNA|DBSCAN-SWA
MKLSQFKFNLPKEQVALYPHSSERVLTRTDGSTQTFTVTRRDEGRLMVLHRKSGKIDMFKGEINGEPKEEDYIRFKDVFNYFDEGDAFIFNDTKVFPARLYGTKEKTDAKIEVFLLRELNQEMRLWDVLVEPARKIRIGNKLFFDESGTMVAEVIDNTTSRGRTLRFLYDCPHDEFKRELFTLGEAPLPRYIIDNRPKEEGEEFAHATADDMEHFQSVFAKNEGAVSAPGTNIHFSEHMMKMMDIKGIKKAFITLHCGLGNFHDIEVEDLTKHKMDSEEMHINADACRIANGAKQAGHRLCAVGASVVKATETAVGTDGMLKEYDGWTNEFIFPPYNFGFADSMLVNFYHPYSTLLMETAAFGGYDLVMEAYDKAVKNGYMFGCFGDSLLILND
>NZ_CP054011|371322:417444|406915_407128_+|WP_004360533.1|DBSCAN-SWA
MKKNVYAVSGMKCVHCKANVENALKALNGVVSAEANLEDANVTVEYDESKVNPSEIKEAVDNSGRYELSL
>NZ_CP054011|371322:417444|377845_379123_+|WP_036886434.1|DBSCAN-SWA
MKRNFLITLFLIVSLGTIAQVNHPISVRSDERPSMDKIQAYIDSLKSLKDSVFTRKMPKVQRGQRLRRNDMRLFLPLTYYGNVAERLFTRDRKESPILSELMHLYLTRPDLVEGTDRMVQQQQTKLDDIKAPIHHDPTLVEKVADRPVEPTNVPVDVLVKRPNFWTFSGDYALQFLQNYVSGNWYKGGESNYSTLASLVMQANYNNKQKVKWENRLELKYGMQSSRSDSLHSFKSTEDLIRLTSKLGLQATKRWYYTVQFIGNTQFSHSYRSNDPKIYSAFAAPLNINLSIGMDYSVDWMNHRLKGNFHLAPLAYNMKYTRMLELTRRLGIKDGNHFLHDFGSEFTVDLEWQLMESLTWKTRLYGYSTYKRTELEWENTFTFHFNRYISSRVFIYPRFDDGVRRDDHYAFWQLKEFASIGFQYSF
>NZ_CP054011|371322:417444|413065_413653_+|WP_172891339.1|transposase|DBSCAN-SWA
MDHAQDWLLFEDNIGESLSIDETCLSSGEVYTFLTNKAGKGRKGTLVAVVKGTKAEDVIQVLKKINLSKRKTVKEITLDLSSSMMRIARAVFPKALITNDRFHVQKLYYDALDDMRIAYRWTARDKENEEIKEAKCKGKEYIPFRYSNGDTRKQLLARAKIILTKHKTKWTETQKGRAQIIFEHYPTLKRHMIWL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004360509.1|371322_372507_-|tRNA	S-adenosylmethionine:tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
WP_004360510.1|372528_373227_-|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_004360511.1|373248_374109_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_004360512.1|374108_374351_-	DUF3098 domain-containing protein	NA	NA	NA	NA
WP_004360513.1|374482_375361_-	ABC transporter permease	NA	NA	NA	NA
WP_004360514.1|376612_377296_+	PorT family protein	NA	NA	NA	NA
WP_036886434.1|377845_379123_+	DUF3078 domain-containing protein	NA	NA	NA	NA
WP_036886407.1|379469_382955_+	SusC/RagA family TonB-linked outer membrane protein	NA	NA	NA	NA
WP_036886408.1|382960_384508_+	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_036886436.1|384549_385182_+	fasciclin domain-containing protein	NA	NA	NA	NA
WP_004360519.1|385184_385658_+	hypothetical protein	NA	NA	NA	NA
WP_036886410.1|385823_387152_+	thioredoxin family protein	NA	NA	NA	NA
WP_036886412.1|387161_390014_+	insulinase family protein	NA	NA	NA	NA
WP_172891336.1|390214_391447_-|transposase	IS4 family transposase	NA	NA	NA	NA
WP_004360522.1|392015_392945_-	cation transporter	NA	NA	NA	NA
WP_004360523.1|392979_393801_-	hypothetical protein	NA	NA	NA	NA
WP_036886439.1|393946_394216_-	hypothetical protein	NA	NA	NA	NA
WP_172891337.1|394463_398213_+	DUF4922 domain-containing protein	NA	NA	NA	NA
WP_004360526.1|398224_399538_+	hypothetical protein	NA	NA	NA	NA
WP_036886418.1|399671_400571_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004360528.1|401167_401617_+	NfeD family protein	NA	NA	NA	NA
WP_013263822.1|401720_402668_+	SPFH/Band 7/PHB domain protein	J3IZE5	Acanthamoeba_polyphaga_lentillevirus	2.5e-19	27.5
WP_004360530.1|402784_403909_+	UDP-N-acetyl glucosamine 2-epimerase	A0A0N9R0B2	Chrysochromulina_ericina_virus	5.6e-34	27.5
WP_004360531.1|404424_405789_+	MATE family efflux transporter	NA	NA	NA	NA
WP_004360532.1|405785_406349_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004360533.1|406915_407128_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_004360534.1|407224_409144_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.6e-81	31.6
WP_036886422.1|409246_410116_-	hypothetical protein	NA	NA	NA	NA
WP_004360536.1|410235_411186_-	aldose 1-epimerase	NA	NA	NA	NA
WP_172891338.1|411563_412481_+|transposase	IS982 family transposase	NA	NA	NA	NA
WP_007369112.1|412605_412950_+|transposase	transposase family protein	NA	NA	NA	NA
WP_172891339.1|413065_413653_+|transposase	transposase	NA	NA	NA	NA
WP_172891340.1|413649_413874_+|transposase	transposase	NA	NA	NA	NA
WP_172891341.1|415563_417444_-|transposase	IS1634 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP054011|514250:572912|DBSCAN-SWA
GATGATTACCAAGGACAAAATTACTGAAATTTTCTGTATTGCAGATGATTTCTGCAAAGAGTTTGAGTTAGAAACTGATAAAATAGGTCTCTCAGAAAAGAATAAAGGATGTCATCGCCATCGCAGGTGGCGTATGAGTAAGTCTGAAATCATAACGATTTTAATTTGCTTTCACTTTAATTCCTATCGTAATTTTCGTCACTATTATACCTTTTTCGTAAAAGAGCATTTAGCAGATTTATTTCCAAATCAATTGTCTTATAATCGTTTTCTTGAATTAGAGGCAAGAGTCTCTGTAGAGATGATGATGTTCCTGCAGATATGTTGTTTTGGGAGGTGTACTGGTATTAGTTTTATTGACTCAACTTGTATTCCAGTTTGTCATAATAAACGTATTTGTCGCAATAAGGTTTTTAGAAATTATGCAACAAGGGGTAAGAGTACAATGGGATGGTATTTTGGATTCAAACTACATCTTATCTGTAATGAAAGAGGTGAGATTCTAAACTTTATGCTCACTAAAGCAAATGTTGATGACCGAGACGAAAATGTATTTAACAGGTTGACAGACAATGTATTTGGTAAATTGTTTGCAGACAAAGGGTACATTTCTCAAGGATTATTTGAGCGATTGTTCAATGATGGAATAAATTTAGTTACGGGCATTAGGAGTAACATGAAAAATAAACTGATGCCACTTTATGATAGACTTCTTTTAAGGAAAAGATCTGTAATAGAGACTATCAATGATGAGCTAAAGAATGTAGCTCAATTAGTGCATTCAAGGCATAGAAGCATATTTAATTTCGCAATGAATGTTCTCTCTGCTATTGCAGCCTACAGCTTCTTTGAGAAGAAGCCAGCAGTGAACATAGACTTTGCTATAGAGCAACATTCGGGACAGCTTACATTATTCTAAAGTAATCTGTTTTATTATTATCTTTAGACCCAATCAAAAGATTGAGTCTAAAGAGCCGTTGTACTAAACCAAACAGAAGAGTGATATGATACTTATCCCGAGTTCAGGTTAATACTTTAGATCTCTTGTTGATGCTTAATAGTAATCTCACGTTGTGGGAATGGGATTTCAATACCATTATTGTTTAACGTATCATAGATACATTCCATAATAACCGCAATGTCATTTCCCTGTGTTAATACATTTAGCCAAACAAGAATCTTCAGTGTGATACAGCTATCATCGAAGCTTTGAAGTCTGACAATAATATCCTTTTTTTCATTAGTGATACCAAGTTTAGCGATAGCATCTTTAAGAAGTTCTCTTACTTCTTTTACATTCGTACCATATGCAACACCAACTTGAATAGTTCCCACCTCATAACCATCATTCTTGGTCATGTTTTTATAGTTCTTAGTGAAGAGTTGTGAGTTTTGGAAAGCAATCGTAGAACCATCAAGTGCATCAATCACTGTCGAGGTATAGTTTATGGAACTTACCTTACCACGTATACCGTCACAGATGATATAATCGCCAATCTTAATACGTCCAGCCATCAAAGAAATACCATAATAGATGTTTTCAAGAATATCCTTCATGGCGAAACCGATACCCGTTGACAAGCCACCTGTCACAACAACTAACCATGTGCTGCTGACTTTGAAGAAGCCAAGGGTAATCAATAACCAAGCTCCCCATACGATTACTTGTAATACGTTGATATACATCGTAGCACGCGCCTCGGCTGTAGATGGGTCATTGCGTTTGAGATATAACTTGATAGCATCTCGAATCGTTAGATTCAGATAATTAAAGATGAACCATAGGATAGTTACCACAGCTATTGAGTAAACACTAATCTGTATCTTATCAGAATCAATAAAGTTGGCACGGAATAAGTTCCATGTCAATCCACTAAGATTAAAGACATCAGTTGCCCAATAAATAGCAAGGATAAATGATATTACCAAAGCTGTTGGAATGAGAACAATGTCAACAAAACGAAGAAGCCACACCTTTGCTGGTGATAGTTTCTTTATTGGATGTTTCTCCCTGTACTGGTTGAGGTAGTCTTTGAAGAAAGCAATTGTAAGAATACAAGCCAACTGCATTGACCACCAAATGATTACCTGAACGGCAAACATTGTGTATCCTATCGATGCACTTATAAGTGAGAAGATGAATACAAATTGAGAGATATATGCAAAGTTTAAGTCGTAATGAGGTACAAGCTTATGATATTTGTGTATCATTCTTGCCTGCCACAATGTGTCTATGAATAATAAAGGTGTGAAGAGAAGAGTTACGACTGAGCTTGGTAGCATCACGATACGAAACGCAATGACAAAGAAGCCAATCATAATCAAGGGATAGTAAATACGGTAAGCATTATGTGTCTGTGAACCTTCTACACGTAGAAGCAATGATGCAAAAATGACAGATAGCATCCATGTGTACTCCAAAAGTAGGCTGCAAGCCATGTGTACGAAGTTAGAAGGCGAGAACAATCGGATAATGATAAGTACAATACTGAATGTAATGACAGAAGCAAGCATAATGATACAAGTACGCTTGGCAAGGAAACTTTGACTCTTCTGCTCGAAACGATTTGTCTTCATAACTCGTGTTACAAGGAATCGAATACTCAGATAATTAATGATAATGGCTATCAAACCATAAATCAGAATCATACTGAAGAGTGTGATAATCCATTTTACATCCCATTGAGATACTACAACAGTGTTTGGGGTATATTTTTCAGAGAGTGTCGTGTTCATCTGACTAAGACGAAAACGAACCGATTTAAGAACCTTGAAGTAGCTATCTCCTGTGTTTGTAAAGATGCCTGACTGAATCTCGGCATAGCGTTTTTGGGCATAGGCATCAAGTGCCTGCAACTGATGCTGGCTGTAATTGTAGTATTGTATATATTCTTGATAAGAATCATTGCGCTCCTTTAACATTCTTCGAATACTTACAGCAAGAGTAAGACATACGTTTCGGTCGGTCTTCATTTTTTGAGTAAGACCGAAGGTATACATCGTACTAAGCACATTGACAAGGGAGTCATAGCGCGCTATTTCTTCGTTACTTTCCGTGATAAGGTCATGAAAAGGACGTGTCTTTGTTTGGAAATCTTTCCATAATTCAGTTGCTTGTTGGCAAGCATAGGTAAGGTCAAAGATGTTGTCCGTCTTCTGTGAATAAAGCATCAATGATACTTGAGCTGACTTATCACCAATTTCTTTTAACTGATTTGTCACTTGTTCAGTTATGAATCTTGAATTATTCAGCTGCTTTGTTTGTTCAAGATGCTGTGCAATCAATTCATGGCGTAGCACTTGGAGTGAGTTTTTCAGTGAGTCCTCCTGCAGTACAGCATTTGCAGGAAGGGTCAGGATGAACAGCAATATGGTGATAAAGAATAGCTTTTTGCGCATATCTATTTGTTGTAAAGAATAGTTTTTATGATTGTTTTAATGTCTACAAAGGTACGCAAAGTTTGTCATTTAGACTTATATCGGAATGTAAAATGATACTAAAGATGTCTTTGTATGTGCTTTTCTTGGGTTATAATTCATATAAATGGATAAAAAATAGTAAGTTTGCACAAAAAAATATACTATGATATTAATTGCTGATAGCGGAGGATCTAAGACTGACTGGGCATTGATTAGCTTGCCCACAGATACAAGTAAGTATGTTCTGAAAGTTCGTACACAAGGAGTAAATCCTTTTCATCAGTCGAAGGAAGTTATTTTGAAGATTTTAGAGCAGGAGCTAAAGCCTGTACTATACAAGGCTGCAGAGCAAAATGATAGCTTTTTACCAAAGAAAGATATAGCAGAATATGTCTCACAGATAGCTTTTTATGGAGCAGGCTGTACAAAGAATCTTTCTTCAGTTGTGAGTGAAGCACTTACGGTTTCATTTCCTTCAGCGTTGATAAAGGTGGAGAGTGACTTGTTAGGGGCTGCACATGCTGTCTGTGGATACGATGCGGGTATTGCTTGTATTTTAGGTACTGGTGCCAATAGCTGTCAGTATGATGGCGAGAATATTGTGGCAAATGTTCCGCCTTTAGGTTATATTTTAGGGGATGAAGGTAGTGGAGCAGTACTTGGCAAGTTGCTACTCAATGGTATTTTTAAGGGTGATTTATCTACAGAGATACGCGATTTATATTTAGAGTGGAGTGGTTTAACCTATCCAGAAATCATTGATAAAGTTTATCGTCAACCGCTTGCGAATCGCTACTTAGGAGGTATTTCTAAGTTTATTAAAGAGAACTTACAATATGCTGAATTAGAATCTTTAGTAAGATTTAACTTCGATAATTTCTTTAAGAAAAATATCTTGAAGTATACAACAACCTCAGTTCGTAAAATTTCTGCTGTTGGCGGTATTGCGGCTGCTTTTGAAGAACAGTTAAGAATGAGTGCCAGTACTTTTAATTTTAAAGTTGGTAAGGTGATAGCTTCACCAATAGATGGATTGATAGAATATTATTCTTAATTTGTTTTCTTTCATGTAAGCTGTCGATAAGATATTTTCATGGACAACTTCATTAGTAACCTAATTGTCGTAAGAAGTAAACATGTCGTATTTGATAGACTTCGTATTATCGTCTTGTAAATCTGCCAATACATCGTTTGTAAAGTGGAGTTTGCAAAAAGTGGTGTGTTTTTCTGCTTAATTTGCACACGTTCTCAAATATTTTTGTATCTTTGCACACGTTTTGAAACATGTTTTCTTAGAGCAAGATTGAACAATTAAATTATAGCTATATAAAGTTTATGTATTTCACACTTTTTGTTACCGTTTTGATAACGGCCGCATTCTTGGTAGTAGCAGCTTATGCTATTGCTAAATGGATTGGTCCGCGTTCATATAATCCGGCGAAGGGTGAGCCTTATGAGTGTGGTATCCCGACTTACGGAACCTCTTGGTTGCCAGTGCATATCGGTTACTACTTCTTTGCCATTCTTTTCTTGATGTTTGACGTGGAAACCGTATTCCTTTATCCTTGGGCTGTTGTTGTAAAAACATTTGGACCTCTCGCACTTGCTACGATTGGTTTCTTTATGTTGGTATTAGTATTTGGTCTTGCGTATGCTTGGCGGAAAGGAGCACTTGAATGGAAATAAGAAAGCCAAAAATCAAGTCTCTTCCATACGATGAATGGAAAGACAATGACACGCTTAGCAAAATGGCAAGCGAATTGAACGATGGTGGAACAAACCTCGTTCTCGGTAACTTGGATCAACTTATCAACTGGGGGCGTAGTAACTCTCTCTGGTCACTTACCTTTGCAACATCATGTTGTGGTATTGAGTTTATGTCTGTTGGATGTGCGCGTTATGACTTCTCACGTTTCGGTTTTGAGGTAACACGTAACTCTCCACGTCAGGCTGACTTGATAATGTGTGCTGGTACTATCACAAACAAGATGGCTCCAGCTTTAAAGCGTTTGTATGACCAGATGGCTGAGCCTAAGTATGTAATTGCTGTTGGTGGTTGTGCTATCTCTGGTGGTCCATTCAAGGATAGTTATCATGTGATGCGTGGTATCGATGAGATTATCCCTGTGGATGTTTATATCCCAGGTTGCCCTCCACGTCCAGAGGCTATTATCTATGGTATGATGCAGCTTCAACGTAAGGTGAAGGTTGAGAAATTCTTTGGTGGTGTAAACCACAAGCAGTCTACTGAGGAGCGTGAGTTGGGCAAGAGTAATGCCGAACTTATCTTTAGTGAGAAGTTAGGTATCAACCCTGAAGAGATTAAGGAGAAGCGTGAAGCAGCTTGGAATGAAGCTAAAAATCCTGCTCCAAAGCCTGCACGTCCTGTTGTGAAGCCTACAGCTGCCGCTGTGAAACCAGCTGATGTTTCTGCTAAACCTGCAGAAGCTGCTACTACTTCTTCTGAGCCTGTTGCTCCAAAGAAAGATACGATTGTCGTTAACCAGCCAGTGACACAAGAAGATGTTGAGAAGTTGGGCAAGGAAATCGATCAGATTGATGCAACAAGTAAGGCTGCAGATGAGACAGCTACTAACAATTAATATATAAGGTACGCGAGAATGAAATTAGAAAATAAAGAATTCGGTTTTGATAGCTTTGCTTCAGAAATGGCAAAGCTGAAGAATGAGAAGCATTTCGATTACCTTGTAACTGTTGTCGGCGAAGACTTTGGTGCAGAGGAAGGTCTTGGATGTATTTATATTCTTGAGAATACAAATACACACGAGCGTTGTTCTGTAAAGCAGCTTGCAAAGAAGGTAGGAGAGGAGCATGTTATTCCTTCTGTCTACAATATTTGGGCTGATGCTGACTTGTTAGAGCGCGAGGTCTATGACTTCTATGGTGTTAAGTTCCTTGGTCACCCAGACATGCGTCGTCTCTACTTGAGAAACGACTTTAAGGGTTATCCACTCCGTAAGGATTATAACATGGATCCTGCTAAGAACATGTATACTACGGAGGATGATGTAGAACTTGATACAACTACAGAGTGGAATCTTAATAACAATGGTGAACTTGTTGGTACACAGCGTCCGCTGTTTACTGATGATAACTTCGTTGTGAATATTGGCCCTCAGCACCCTTCTACACACGGTGTGCTTCGTCTGCAGACGGTGTTAGATGGTGAGACGGTAACCAAGATCTATCCACACTTGGGTTATATTCATCGTGGTATCGAGAAACTGTGTGAACAGTTCACATATCCTCAGACCTTGGCATTGACTGATCGTATGAACTATTTGTCAGCAATGATGCACCGTCATGCGCTCGTTGGCGTTATTGAGGAAGGTATGGGCATTGAATTGTCAGAACGCATCCTCTACATCCGTACAATTATGGATGAGTTGCAGCGTATTGATAATCACCTCCTTTATACATCTTGTTGTGCTCAGGACTTGGGTGCACTCACTGCTTTCCTATATGGTATGCGAGATCGTGAGCATGTCTTGAACGTTATGGAGGAGACAACAGGTGGTCGTCTGATTCAGAACTACTATAGAATAGGTGGTTTGCAGGCTGATATTGATCCAGACTTTGTTTCAAATGTTAAGGAACTCTGCAAGTACCTACGTCCAATGGTTCAAGAGTATCTTGATGTCTTTGGTGATAATGTCATTACCCATGAGCGTTTCCGTAATGTTGGTGTTATGGATGAGCAGGATTGTATCAGCTATGGTGTGACTGGTCCTGCTGGTAGAGCAAGTGGTTGGAAGAATGATGTTCGTAAGAATCATCCATATGCTATGTATGATAAGGTTAACTTTGAGCAGATTACCTTGACTCATGGTGATTCTATGGATCGTTACTATTGCCATATTCAGGAGATTTATCAGAGTCTCAATATTATTGAGCAGTTGATTGACAATATTCCTGAGGGTGAGTTCTATATTAAGCAGAAGCCAATCATCAAGGTTCCTGAGGGACAGTGGTACTTTGCTGTTGAGGGTGCAAGTGGTGAGTTTGGTGCTTATCTGGATTCACGTGGTGACAAGACTGCATATCGTTTGAAGTTCCGTCCTATGGGTTTGACACTTGTTGGTGCTATGGATAAGATGTTGCGTGGTCAGAAGATTGCCGACTTGGTGACTACTGGTGCTGCGCTTGACTTCGTTATTCCAGATATTGACCGCTAACAAGGTTATCATTAAAGTAATCAATTAAGAATTAAAATCATACTATGTTCGATTTTAGAATAGTAACAACATGGTTCGATGAGTTACTCCGCGTCACTTGTGGCTTGAGTAATTTCTGGACCGTTCTGATTGAGTGCGTTGCGGTGGGACTGGCAATACTTCTTGCTTATGCTTTGCTTGCAATTGTGCTTATCTTTATGGAGCGTAAGGTCTGCGCCTACTTCCAGTGCCGTATTGGTCCTGTCAGAGTAGGATGGTGGGGTACCTTACAGGTCTTTGCTGACGTATTGAAGATGTTGATTAAGGAAATCTTTGCTGTTGATAAGGCTGATAAACTGCTTTATTACTTGGCGCCATTCCTTGTAATTATTGCATCTGTCGGTACATTCTCTTTCCTTCCTTGGAATAAGGGAGCTCATATCCTTGATTTCAATGTCGGTATTTTCCTTGTAACAGCCATTAGCTCTATTGGTGTTATTGGTGTGTTTATTGCAGGATGGGGTAGTAACAACAAGTATTCTGTTCTTTCTGCTATGCGTGGTGCCGTACAGATGATATCATACGAGTTGTCATTAGGTATCTGTTTGATTTCAGCAGTTATTCTGACTGGTACTATGCAGATCTCAGGTATTGTTGAAGCACAGACAGGTCCTTTGCAGTGGTTGATCGTACAGGGACATGTTCCTGCTACTTTGGCTTTCCTCGTATTCTGTGTTGCTGGTAATGCAGAGGCTAACCGTGGTCCATTTGACTTGGCAGAAGCTGAGAGTGAGTTGACTGCAGGTTACCATACAGAGTATAGTGGTATGGGATTTGGTTTTTATTACTTGGCAGAGTACCTTAATCTATTTGTTGTAGCAGGTATTGCAACTACTGTATTCTTAGGTGGTTGGGCTCCTTTGAACATTGGATTAGATGGCTTTGATGCTATTATGAATTATATTCCAGGTCTTGTTTGGTTCCTTGGTAAGACATTCACAGTAGTATTCTTGCTGATGTGGATTAAGTGGACATTCCCACGTCTCCGTATCGATCAGATTCTGAAATTAGAGTGGAAGTATCTTATGCCACTATCATTGGTTATCCTTGTGTTGATGACGGTGTGTGTTGCATTCGGTTGGACGATTCACTATTAATGGTTAAAGAGAATGGAAGATAAAAAACAATCATATTTTGGTGAGGTCGGGAGCGCACTCAAGACACTTGCTACGGGTATGAAGGTGACCATGAAGGAATACTTCACACCAAAGTCTACCGAGCAGTATCCTGAGAATCGCAAGACAACCCTTCACGTAGCCAAGCGTCACCGTGGCCGTTTGGTCTTCAAGCGTGACGAAGAAAAGAATCACAAGTGTACTGCTTGTACAATGTGTGAGAAGGCTTGTCCTAATGGTACTATCAAGATTCTTTCTGAGATGGTTACCAACGAAGAGACAGGTAAGAAGAAGAAACAGCTCGTTGATTATGAGTATGACTTAGGCGATTGCATGTTCTGTGAGTTGTGTGTTAATGCCTGCAACTTCGATGCAATTGAGTTTACGAATGATTTCGAGAATGCTGTCTTCGACCGTTCTAAGTTAATCCTTCACCTTGACAAGGAAGTATATGAAGGAGGTTCACTGCCAGGTCTTATCGACGGTGGTGCAGACTGGAAGGTAGGAACATTCAATACTAAAAAGAAATAAAGGTTTAGAGATATGGCAAGATTAATTATGTTTGCGGTTCTCGCCGTTATTATACTGGCTTCAGCCGTATTCTGCGTGTCGACGAAGCGTATCATGCGAGCTGCAACAGCATTGCTGTTTGTGCTCTTTGGCGTTGCAGGTCTCTACTTCCTGCTCGATTACACATTCCTTGGTGCTGCCCAAATCAGTATTTATGCTGGTGGTATCACAATGATGTACATTTTCGCTATTCAGTTAGTAAGTAAGCGTACATTGCAGGGTCTTTCTGAGCGTTGGTTAGGAAAGCGTACTTTCCTTGCAGCCTTCATTGCTTTAGTTGGTTTTGGTACAGTAATCCTTGTTCTGTTAAAGAATCAAGTTCTGCGTCACACTGTAGTGAACGGTGATTCTTTATCAAATGAAGTTACAATGGAAACCATCGGTCGTAATTTGATGACAGCCAATAAGTATGGTTATGTTCTCCCATTTGAGTTCATCTCTGTATTCCTTTTGGCTTGTATCATTGGTGGCTTAGTTATATTGAATAACAAAAAGAAGGAGGAAAGCAAATGATACCAGTAGGATATTTCTTTGTCCTTAGTGGACTATTGTTCTTTATCGGAGTGTTTGGTTTTGTAACCCGTCGCAACCTTGTTGCAATGCTTATCTCCGTAGAGTTAGTTCTCAATAGCGTAGATATTAACTTTGCTGCGTTCAACCGTCTACTTTTCCCTGATGGATATGAGGGTATGTTTTTTACGCTCTTCTCTATCGGTGTAAGTGCTGCTGAATCAGCTGTTGCACTCGCTATTATCATCAATGTTTACCGTCATTTCCACAGCGATCAGGTGAACAGTATTGAAAATATGAAATTATAAAGAGAAACAAATATGTTTGATTACGCATTTTTGATACTTCTTCTCCCGTTCCTAAGCGCTGTTGTGCTTGGCTTGTTCGGTATGAAGATGCCTCGCAAGGTCGCTGGTATAATCGGCACCTGTATGTTGGGAACACTATTTGTGCTTAGCCTCTACACTGCTTACCATTATTTCTTCTATACTGGTGAGTATACAGCTATGGGCGAGACCTTCAATGTAACTGATGGTCGTTTGGCAAATGGTACATACCCAACTGTTACAGTCTTCAACATTACATGGTTGAAGTTTACTGAACTTTTGACTTTTAACATTGGTTTCCGTCTTTCTCCAATCAGTGTGATGATGTTAATCGTCATTACGACTGTCAGCTTGATGGTTCACATCTATTCATTCGGTTATATGGCTGAACGTGATGAGAATTATAAGTTTGAGGAGTATGAGCACGGCTTCCAGCGTTTCTATGCCTACCTATCACTCTTTACGATGTCAATGCTTGGCCTTGTAGTGGCAACTAATATTTTCCAGATGTATCTCTTCTGGGAGTTGGTAGGTGTATGTTCATATCTGTTGATTGGATTCTATTATCCAAAGCATACTGCAGTTCATGCCAGCAAGAAGGCTTTTATTGTCACACGTTTTGCTGACTTGTTCTTCTTGATTGGTATTTTGTTCTTCAGCTTCTATGTTGGCACATTCAACTATGATCTTAATGTTAATCCAGGTCTTGCTGAGACACTGAATGGCTTGGCTAAGAACCCACATTTGACTTGGGTACTCCCAACAGCTCTTTTCTTGATGTTCATTGGTGGTGCAGGTAAGTCAGCAATGTTCCCATTGCATATCTGGTTGCCAGATGCTATGGAGGGCCCAACACCTGTATCTGCATTGATTCACGCAGCTACGATGGTTGTTGCTGGTGTATTCCAGGTTGCATCATTGTTACCAATCTATGTACAGTTTGGTGCACAGGAGCAACTCCATTGGATTGCTTGGATTGCAGCATTTACAGCCTTCTATGCAGCAGCAGTAGCTTGTGCTCAGCGTGATATTAAGCGTGGTTTGGCATTCTCTACTATCTCACAGATTGCTTATATGCTTGTTGCGCTTGGTGTTTGCTTCTATGAGAAGGAGCACGGTTCATTCTATAGTGCAGAATATCTCCACCATGGTGGTCTCGGCTATATGGCAGCAATGTTCCACCTCTTCACTCATGCAATGTTCAAGGCTCTGCTCTTCCTTTGCTCTGGTGCTATTATTGTTATCATTGGTAGCAACTTCAAGGAGTATATGGGTGGATTACACAAATACATGCCAATTACGAATATCTGTTTCTTGATTGGTTGCTTGGCAATTGCAGGTATTCCTCCATTTGCAGGTTTCTTCTCTAAGGATGAGATTATCTCAGCATGTAATGCACTTCCTGGTGTAGAAGGACAGGCTTTAAAGTGGATTATGACACTTGTAGCTGGTATGACAGCATTCTACATGTTCCGTCTCTACTACGTAATCTTCTGGGGTGAGTCTTACTATGAGCAGGACCCAGAGAACCGTCGTCGTCCACAGGAAGTTCCTTTCGTTATGTGGGGTCCATTGGTATTCCTCGCAATTATTTCTATCACTGCAGGTTGGATTCCATTTGGTCACTTTGTAAGTGCTAACGGTCTCAACTACGATATCCACCTTGATTGGAGCATCGCAACTACCAGTATTATTGCAGCAGTTATCGGTATCGCACTTGCAACTTGGATGTACATGGGCAAGAAGCAGCCTGTTGCTGATGCTTTGCAGCGTACATTCCCACGTTTGCACAAGGCTGCCCTCAACAGATTCTATATTGATAATGCATGGCAGTTCTTTACACACAAGATCGTATTCCGTTGCTTCTCTATTCCAATCGCATGGTTCGACCGCCACGTTATCGATGGTACGTTTAACTTCATGGCTTGGGGTACACAGGAGGCTGGTGAGTCTATCCGTTCATGGCAGAGTGGCGATGTTCGTCAGTATGCCGTATGGTTCATCACTGGTACTGTAGCATTAACATTAGTATTACTTTGCTTGATTTAAAGAAATGAGTTGGATATTAACTGTATTTGTAATTATCCCCGTCCTGATGCTTTTCGCTCTTTGGGTAGCGAAGAATGATAATCAGGTACGCGGTGTGATGGTAGCCGGCTCTACGGCACTTTTGGTAGGTGCAATCTGGCTGACTGTTTATTTCGTTCAACAGCGCAACGCAGGTAATCATGATGCGATGCTGTTGACAAACTCCGTAATGTGGTTTAAGCCTCTAAATATTGCCTTCTCGGTAGGTGTAGATGGTATCTCTGTCGTAATGATTCTGCTTTCTGCAATCATTGTCTTCACAGGTACTTTTGCCAGCTGGCAGCTTGAACCAATGAAGAAAGAATACTTCCTTTGGTTTGTACTCTTGTCTTCAGGTGTATTTGGCTTCTTTATCTCTACGGATATGTTCACCATGTTCATGTTCTATGAGGTTGCGCTGATTCCAATGTACCTCCTCATCGGTGTATGGGGTACTGGTCCTAAGGAGTATTCAGCAATGAAGCTTACCTTGATGTTGATGGGTGGTTCTGCTCTCTTAGTACTCGGTATCCTTGGTATCTACTACTTTAGTGGTGCTACCACAATGGATGTAATGGAGTTAGCACGTATGCATGCTATGCCTAAGAACATTCAGAACATCTTCTTCCCATTGGTGTTTATTGGTTTTGGTGTACTCGGTGCATTGTTCCCATTCCACACATGGTCTCCTGACGGTCACGCTTCAGCGCCTACAGCAGTATCAATGCTCCACGCTGGTGTATTGATGAAACTTGGTGGCTACGGTTGTTTGCGTATTGCAATGTTCCTTATGCCTGATGCATTGGAGATGTGGGCACCAGTATTCCTTGTGTTGACAACAATCTCTGTAGTATATGGTGCACTTTCAGCTTGTGTACAGACTGACTTGAAGTATATCAATGCTTATTCTTCAGTTTCACACTGTGGTATGGTACTCTTTGCTTTGGTTATGACCACGCAGACAGCTATCACAGGTGCAATCCTCCAGATGCTTTCACACGGTTTGATGACAGCCTTGTTCTTTGCATGTATCGGTATGATTTATCACCGTGCAGGAACACGTGATGTTCGTTACCTTGGTGGTCTTATGAAGGTTATTCCATTCTTGGCTGTATCTTATGTAGTAGCAGGTCTTGCTAACCTTGGTTTGCCAGGTTTCTCAGGCTTTGTTGCCGAGATGACAATCTTCGTAGGTTCATTTGAGAATACAGGTACATTCCATCGTGTAGCAACAATCATTGCTTGTACAGCAATTGTAATCACAGCTGTTTACATCTTACGAGTGGTAGGAAAGATTCTCTTCCAGAAAATTCCAAACAAGAAGTTCTATGAGTTACATGATGCTACATGGGACGAGCGATTCGCTATCGGCTGTCTAATCTTCTGCGTTGCAGGTTTAGGTCTCTGCCCACTCTTCTTTGAGAATATGATTATGGACGCAGTTCATCCTATCTTTGATCACATCTTCACATATATACCAAATTTGGGTAATCTTTAATAAACTGGCGAAATGAATTATAGTGATTTCTTTAAGATGATTCCGGAGGCAAGTCTCATTGCCATCCTGATTGTTTTGTTCGTTGCTGACTTTGCAACGGCAAAGACTGAAGAACGCAAGTGGTTCAATCCGCTGGCTTCTGTACTCTTGCTTTTGAACACCTTCGTGTGTCTTTATCCTATGGGCACACAGAGTCTGTTCGGTGGTATGTATGAAACAACACCTGCTGTTGATGTGATGAAGGCTATCCTCTCTATGGGTACCTTTATTGTTGTCGTTCAGAGTCGTGTTTGGGCTGCAAAGAGCGGTAAGGAAGCTGAGTTCTATATGCTTATCGTTTCAACATTGCTCGGTATGTTTACCATGATGAGCGCAGGCAACTTCCTGATGTTCTTCCTTGGTCTTGAAATGGCATCTGTACCTTTGTCATGTACTGTTGCCTTCGATATGTATCGTAAGAACTCTGCAGAGGGTGCAGCTAAGTTTATCTTGACAGCAACCTTCTCAAGTGGTGTAATGCTCTATGGTATCAGCTTCCTCTATGGTCAGTTTGGTACTCTCTACTTCGATGATATCGCTACAAAGATGCAGGCAACCCCATTGGTAATCATGGGGCTTGTGTTCTTCTTCAGTGGTCTTGGCTTCAAGATTTCTCTTGTTCCATTCCACTTCTGGACAGCTGATACCTATCAAGGCGCACCAACAACTGTTACTGGTTATTTGAGCGTAATCTCAAAGGGTGCTGCAGCCTTCACATTGTTGAGTATTCTCTTCCATGTCTTTGATGGCATGATGGAGTATTGGCACGTGTTGCTGATGATTGTAGTTGTTCTTTCAATAACCATCGCCAACCTTTTTGCTGTACGTCAGAATGAGTTGAAGCGTTTCATGGCTTTCAGTTCAATCTCTCAGGCTGGTTATATTATGTTGGCAGCTATTGGTAATAATTGGGCAAATTCAGTTGCTGCACTTAGTTACTACGTTCTGATTTATGTTGTTGCTAACATGGCAGTCTTCACAATTATCTCTGTTGTAGAACAGAATAATGGTGGTAAGACCAATATTGATGATTACAATGGTTTCTATCAGACTAATCCACGTCTGAGCTTCTTGATGACCTTAGCGATGTTCTCACTCGGTGGTATTCCTCCGTTTGCAGGTATGTTCTCTAAGTTCTTCATCTTCATGTCAGGTGTTAATGGTGCTGACATCAACACCACAATGGGAGCATGGGCTTACGGAGTTGTATTCATCGCTTTGCTCAACACTGTTATCTCACTCTACTACTATCTTAAGATTGTAAAGGCTATGTATATTGTTCGTACAGACAATCCATTGCCAACCTTCAAGAGTGACTGTAACACTAAGTTCGCTTTGGCTATCTGCATGGCAGGTATCCTCCTCTTCGGTGTTTGCAGCTTTGTATATGAGTGGATTGCAGCAGCAGTTTAATAGGCTACAGACTTATTAAATAAGTATATAAATCGCCCAAGGGTTTCAATAAATCCTTGGGCGATTTTTGCTGATTATAGGTTTTAATGAGATGAGATATAATACCGCTTTTTGTATCAGTTAGTCATTAATCTCTTATTATATGATGATTATAATGCCCTTTCCCTCTCATCTTTTTCTGATGTATTATCCCAAATCGCTCATTAGATCCTAAACATATTTTGTTTTATTATCGAGTAGATTGTTTGACTTTGTAATGCAGGCGTAGCGGGCTACGTCAAGTTATAAAGACAGACAAGATGCCGATAAGAAAATAAAAGATCTTAGGAAACAATACCATAGTAATAAGAATTATACATATTGTGGTCTGATAACCGATTTGGGATTATTATTTAGCACATATCGTGTTTGTGCCCAGCACGTGTTGTGCTGATAGTAAACACAAATGGTGCTGAGTGCAAATTAGCTTGCAATAGGTTATCAATTGCTCGCAATAATGTTTACATTAATATAGTCTTATAAGCTTCAAAAAAGTAATATTGCTGTCCGATAAAACCTCTACATGCTGCAATACTCTCTCTCAATCCTGCTGAAATAGGCATGATTAGTTCTAATTTCAAATTCCAAGCCCCCCTAGAATAATGACAACTCTTCTGGTGGGGCTTTTACCTGGGTAATCAATCTATCCCAGTCTCTATGTGGCTGCTCAAAGAATCTTTGTATTGAGACATAACTCATAAGTAGAATTCTTATCATTGTTGCCAAGCCTGAGAAGCTCCAAGGTCTCTTTATTTTGTTCTTTATTAGTGTTATAAGCAGATTGGCTATAAGCGTAATCCATATTTGTATTTTTATAGTATTCGCACTCTCTCCATAGAAGTATCTTAGCGGGAAATTCTGTTTTATTTGTTTAAATAAGGTTTCTATTTGCCATCGTCTCTTATAGATAGCTATAATATCTTCTGTCGACATCTGAGAATCATTGGTCAGCAGAGATATTAATCTGATTTTCCCTTTCTTAGTCTTATCCTGATATGTGATTTTTCTTGCTTTATGGTAGATATCTTTTTCCTTTGTATGCTTATGAAAGATAATGGTTTCTACACGTACAGCTCCATAATCTGTTGTCATCTCATAATCTGTATCAGCAATTCTTTCAAAGCTAAGATTACTTTTCATCTTAGTTACATATATAACGCCTCTTTGCGTGAGTTCAGAGAACTTTTCATAGTTTATATAGGCTCTGTCAAAAGCAATCAGTTCCTCATTGGCGTATCGTTCTGGGATAAGTGCAAATTGATCATGACTAGCTGCAGATGTGAACTTGATATCGCTTGGAACATTCTCATTGGCAAATATCTCTGTATGTACTTTTATTCCACCCTTTTTCTTACCAGTTTTGGGATTACGTCCTACTCCTTTAAAGACCAGGTTAGAAAACAGACTTATTGTCGTAGAATCTATTATCTTTAGATTCTTCAGCCATTTGGGCTGTCCACAATTTCGGCTGTCCGAGTAAAGTTCATGGCGGTATTTCTCATATAAGTTCATATAGATTGAACCGAATATCTCGGAATCTCGACGTTTGTTTGCATCTGACAAGGTACTTCGATAAGGAAAATGCTTTAAACCAAGATGATTAAAGCGATTAACATTAGCAAAGAGAGAGGCCTTTATCTCACGCAGAGAGTCTAAACGCATCATTACTGCATAAAGCATGACGACAAGATGATGCCATGCATCAAACTTCTTTATATAGTGTTCACCTCCCTGAGCTTGGCTCAGAGATGCAAGTTCCAAAACGAAGTGCAATAAAAGAGTGTCCCTCTCCGAGCAGATGTACGACACCGCGAACCAGCATATCTATGACATGTTGAGCGGCGGAAAGAGCCTTGCCAAACAGCAAATTACAGAACGAATGGCTGAAAAAGGCTTACCTTCGGACACTGTTTTTATGAACCTTTTTTGGAGAATGCCGAATGCGAGGCACTCATTTGCAGCGGCCCTGAAGTGGGAAACGCACATACCTACATGCTCTTAGACGAGCGAGTAGCCCCTATACCCTTACCCACAAAAGACGAGGCGTTGAGCATATTGGCACGCAATTACTTTAGAAGTCATGCCCCAGCAACGTTAGACGACTTTTGTTGGTGATCGGGATTGTCAGTGAAAGAGGCGCGATTGGGCGTTGAAATTATTGAAAAAGAGTTTCAAAAGGTCGTTTTCAACGATAAAACTTATCTGCTGCACGAATCTTCTTCAATCGACATCAAAGAGAAAGAAAGATTTATCTTTCTGTCTGCTTACGACGAATACATCATTGCCTACAAGTATCGCGGCGATGTTTTGCAAGCTTCTCACAACAGCAAAGCATTTACTAACGGTGTTTTCTTTCCCCTTATCCTACAAAATGGTAGGGCGACGGGTAATTGGAAAATGACTTTGACACGCCGAAACATCTCCATCAACACGTCTTACTTTGATAACAACGCCCCCAACAAATTTGTCTGCGGCTGAAGAAAAAGCCCGTTTGCAACTTATTTCGTTCCATAACTAACGGTAAAGATACCGAAGTTATCGAGTTTCATGCCATATTTGGTTAAGCCATAAAAGGCGAAAAGACTGTCTAGTTCGCGTTGCGAACGCCGCCGCATAATCCAATCACGCTCTTGATGGTTGTTTAATACGAAAGCAATCATTTTTAACTGAGGGTGCCAAGGCTGACCAGTATAGACCAAAAAGCCGCCCGGTTGCAGTGCGGATAAAGCACCAGAGATGGCCTTACAAACAAGCTCGTTATCACCAAACAGCTCAAATATACCAGAAATAATAACAATATTAGGTTCAAAATTCAGCTGTCGATATGAGTCTTTATTAAAACAATCAAGACGAGTAAACCGTATATTTTGAAGTCCTTGCTGTTGTATCTGTGCCTCGCCGAAAGCAATATTTGCTTCCGAAAAGTCGTTTATAACCACTTCTATTTCCGGAAACTTGCGTTTGATGTCGAACAAATAATTACCCGTCCCACCGGCAATATCGAGTATTTTCACGGGTTCATTGCGCTGTTTAAACGTTTCAATACGCTCTTCTACGGCTGCGATGAGATGCTCTCGTCGTATTCTTACTCCTCGCCAACCAATGGCGTTAAGATAGCCTTTGTCTATCCATCGCCCAATTGGTCCGCATCCCTGTGCTTGGTTGCGATAAACATAATCCAGAGACATACCCGAATCAAAACCATATTTTAGTCCCACACGCATTCCTTTACTAAGAAATCCCAAGTGATGGAGCATCCATTTCTGCATCCGAAAGCCCCAACGTTCAATTCGGGGAAGCATATTCAAAGTCATTTTGTTATACTCGTCAACTGTAAATTTATCAGGCATACAGGTCGCCGGCGGTTGTTCGAGTGAGAAACAGCGGTTAATAAACTCAGCAATAGGATTGTAAACCTGCTCACGTTGCGTTTCAAACAATAGCCCGTGATAAAACCCTTTAAGCTTGACAAACCGCTTTTGGGTGGAGCTGATGTCAACAAAAAACCGCTTTTGCATATCGTCTTTCACCACGTAGTCTTTACCGGCAGAGAGCAATAGCGTCGGTATGGTTATGGCAGCAGCATCTTCTACTATACGCTTTCCTGCTTTCAGCAAATCCAAGAGATAGTGCGCATCAATTTCTCTAGTAATTAGCGGGTCGGTGTCGTACGCCTTTTGCTGTTCCACATCATGTGTCAACACCTTCGATTTTACATAACTGGGCACTGTTAGGTGTTTGAAGAGCCGCGCTGCCAACGCAATTCCCGTCTTTGCAAAAGGCACATATAACTTAATGGTAAACGCAGGAGCAAGAAGTGCCATACCAGCAATACGGGGCGCAAAGTCGTGACACCACGCCGAAACAATTACACCTGCAATGCTGTTAGCCACCACAAAGATGTCTCTCTCAACAATTCCATACTGCTCATAGAGGTATTTTACGAAAGCATCCAAGTCGCGTACATAGTCCATAAAATGGGGCGAAACGGATTGCGAAGTATGCCCCAGTCCACGCATATCAAAGCCAAAGATGTTGAAATGCACAAATTGCTCGTTCTCGGCAAAGGCTTGCAAACGTCCCGAATGTTCGTGCCCGCGATGCAATATCACAATGGTTTTCTGCGAAGGGTTGTAATTCCACACCCTATAAAAAATATCTGCGTTGTCAAAACTCTTAAATGTTCCTGTTTCCATTTTTATCTTTGGTTAAATTTTTACTTATCATTAACTGCACCGTTTCACCTATTCGGCGACTCCGAAAACGGCCCATTGCACAATGAATATATAGCTTTCGAGGCACATCTTCGGCTTTCATCTTCTCTAAAACCGTATTTACAATACGCTCCTCACAGGCTTTGGGGATAGTGGCAATATCCAAAAGCGGAAAGCAATGGTAATCTGCCGATGTGCGAAAGTAGGCGTTTTCGGGTAATTCGGCTGAAAGGTCGAACACCGAAACCTCTCCCAACATGGCGAATTTCCGAGCAGAACGGCATGAAAGCAAGCCTCCAACGAAGATGTTGGGTGCAATTTCTACAGGTGCCTGACGAGAAAACACCCACAATATGCGATACACTGCGATATAGGGAAAATAGAAAATATAACGCAAAAAACCGATGCAACCGTGGTCGTCTTTAAGAAAATGTCGATTAGAGCGATAATAAGCACGGCCCAATAAAAGCAAGACGAGTATGCCCCACAATAAAAAAATACTTCCTAAAACCGAATGTTCGATGGCAAACAATAACGCCGTCAACCCCACAGCGGCAACAAAAAAGTAAACCGTTGCTATTTGTTGGTTGCGCTTTTTACGGTAAGGAAACATCCATAACGTCAGAAAACCTGCCATCAAACCGGTAGTAATATCGATGAAATGGTGCTGATACACCAAAAGGGTAGACAGCATTAACAACACCAACCACATTCTCAGTAAGTTTCTGAACCTGCTATTTCGCACCCCACTCCAAAAGATGCAGGCATAACCTATATGTAAAGACGGGACCTGATTAAAAGGTGTATCGTACGTATTGATGAAAGAAAACAAGATATGGGCTGTTTCCGGACGTACAAAACTTTGTTTTAACGGAAAGATAATAAAACAAATTCCCGATAAAACGGTTATAAAAACGATGCGTTTACTTAATGTCGACAGCTGCCGAAAAGTATTGCAGAGGAAGAAAACCCATATAAAAAACACCACACTACTGCTATAAAAATAGATGGCAAAAGGTACAAACGGTATGGCTTTTTCAAACGAAAAGCAAAGCGAAGACACCTCTTTAAGCGATGCCGCATAGCTTGCAGCAAAAGTATAAACAGCATAGAATACACCCCAACAAATAACAAGGGCGATGTATTTGCTTACTTGCAAGCATTTGTTATCTATACCGCAACGCTGCATCAAACCGTTTGGCAAGGGCCGCTTACACGTCCATACAGTTTTGTTGTTTATTTGGGAATGCTCCATAATGTCTTTCGGTGCATAAAAGCCGATAACAAACAAGTGGGTAAAAGCGAAAGAAAAGCGATGGAAAGGCGCATTTTTGGCGGAAACACCACCTGTTCTTTGCGCTGCGCTATGGCTTTTGTCATTGTTTCAACAGCCCGATTTAAGGGCATGCAGAACGGACATTTGGAAAGGTTATTACGGTATATCTCTCTCAATCGTGGCGTGTCTATGTAGCCCGGAACAAGTGTTGTAACCGTTATTTGATAGTCGGCAAAACTTCGGCGATAAGCATCGGCTATCTGTATCAATGCTCTTTTGCACTTGGCATATACGCTTGCGCACGGATAATGCAACAATCCTGCCACCGAAGCAATCACTACCAAATGTCCGCCGGATGCATTCATTGCTTCTCGTGCCACTTCCATCGCATTCAATGCACCCGCGATATTAACCTTCAACATTTGTGAAGTCTGCTCAAAATCCACTTCTTCAGTAACGCCGTTACGGTAATATCCAGCAGCAACAATCATCATGTCCAACCCCTTATCGGCACAAAACACTTCTACGGCAACGGTTAATGCGTCCTTATCACACACATCCAGCTGGTATGCAAGCAACAGTTTGTTAACCTCATCACTCCTGTCTATTCGTGCCGTATTTCGTCCGCACACCCCCACCCGATGGCCTTTGGCAGCATAAAACCGCGCCAAGGCCAAGCCGATACCCGATGTTCCGCCCGTAATAAAGATGTTCATACCTGTTTGTTTTTAAAATGTTGGGCAACCCTATCGTATCCGTATTGCCATTGAAAGTTCATATCTTTTACAAACTGAGCATAGGTTTTGGGCAGTTTCAGTTCTACCTGGAGCTTCAGAAGATTGATGTTTTTTTCGATGTAATGGCCCGAAAGTGCCTGGTTCATGTCGGCCGTGTCTACCCAATAGTTCACCGAATGCGTCATCACTTCTTGCAATCGGCGGTTTCCACTATATCCAAATACGGCTCTAATAAGTGCCTCGTCGATGGTGCCAAACCCCTTTTTCTTCTCAAAGATAATTGTTTCGCCAAGTTGTTCGGCCAGTTCTATGGGCATCAAATCAATAATTCCGCCCGCAAAATAGGCACCTTTGTAATGCACGGGCTGAACGTAGAACATATCCGAAACAGATATTCGGGTGGCAATGGGTAAGGGAACATCTTGAAACAGCTCAACTTGCGAGTCGATGGCACTACCCTCATAGCTTTTAAAATTGCAGTTAACAGCCAGCAAATCGATGTTTCTAGCTGTCTCGGCATCGGTAAAAAGCACCTTCCGATAAAGTTTTCTTCCGTTTCTTTCTTTACCGATGTCAGCCCTGTCAAACAACAATCGGGCACCTACTACGATGGTGGGAAGGGTTGGTCGAACAGCCAACGAGGGCAAAAGCGGGCGTATGTCGGTGGGCATGTCTACGATAAATTTATCGAAAATATTTTCTATATAAGGAGCATAGAATGTGTTTCGCACCTTGCGCTGGCAATAGACACCTATCTTATACAGCATTTTGAAACGTGTCATTCGGGTGTTTTGCACAAAGCGATACAGCTCTTCCGACTGTATAAAGGCCTTTCGCTGCTCGTCGGTAGCAAACGAGTTGATGATGTTGGCAGCGATACTGCCACCGCAAGCGGCAATCAGCAGGTCGGGCTTTACACCATAATGTTGCATCGCCGCATACATGCCGAGATACAAAGCATAACGTGTACCACCGCCAGAAAAAACCGCAACCGTTGGATAAGGTTTCTTTTTCATACTCCACTGCTTATCAATACCATCGGTTTACTCAGGCGTTTGCGAATTCCTGGTTACTTTTAACGTCTTCTTTATCCTAATCCACGTGCTGAGTACAAGCAACAAATCGATAACCCCAAAGATGTAAACGGAATATCCTGAAAGGTTTATACCAAACAAACAGACCACCCCGTAGAGGCCGAGAACGAAAGCACGGTCGCTCTTGCCCATCGGACCATCATACCGTCGTTCTGCCGACAGCACCTTTCCCATCACTCCTGCGTATTCATTAATAATGCTGAGGGCAATGAAAGCCACAATAAAATAAAGACTTTCGGGATGATACTTCAACAGCGGAAAATAAATAATGGTGTCCGAAACGACATCACCCACTTCGTTTAACAGCTCTCCCTTTCGGGTTATTTGATTGTAACGACGAGCCATCATGCCGTCTAAGGCATTCAGGGCCATACGTATCAGCAGTCCCACAGGCAGGCAAAGGTAGAGCCATGTACCCACATCGCCCGCAAACCAAAACAAAATGCCGATGACAAGTGAGAGGACACAAGCCCACAAGGTGATTTGGTTGGCAGTAACTTTTGCACGATGCAACAACTCTAAAATAGGCGTTAACACCCGTTGAAACTGCGGTTTGATGGAATAGACAGATATCATAAGTACTTTGTTTTACATGAACATTCTTAATTCCGCAACACTATTATAAATTAAACTTTTTAAGTACCAGAGCAACAAAAAGTTGCTCAGGATTTTGCCATGTCAGAGTTTTCACTTATCTTAGTGTTGCAAAAAAACAAGAGAATCCGACGATGGACATGGCAAAGATACAAATTAAATCTGAGAGACTCACTCCTTTTGGGGTGTTATTTTCAATCATGGAGCAATTTGACTCCACACATTATCATCTGTAATCGACTCAACCCTCGGTCTAAGGTGTAGATCGTTCGGTTATCAGTACAGCGAAATCATTCGTTCTCTCATGAGTATCTACTTCTGTGGCGGATCATGTACCCCAGGATGTCACTACTCATTTGATGAACCACCTCTCGCTTCATCTGACACTTCGCACTTGTAGCTCTGATACTATCCTCAGAGCGATAAAGGAGTTGACGCAAGAAAACATTTCATACACATCAGATATGGGCAAGACCTACGATTTCAATACGGCTGACACTCTCAATACTTTATTGCTCAATTGTATATTTGCATCTGGCCAACTGAAAGGGAGTGAGATGTATGATGTTGATTTCGACCATCAGATCATAGAGATAGAGAAGTATGATGCAAAGCCTACATACAAGAAGTTCTTTGGTTATCGCCCTGGCGTGTCGGTTATTGGTGATTTGATAGTCGGTATAGAGAATAGCAATGGTAACACAAATGTTCGTTTCCATCAGAAGAACACGCAGAAGAGGTTCTTTGAGAGATTTGAACAGAATGGGCTCATTATCAATCGCTTCAGAACTGATTGTGGAGCATGCTCCAAGGAAATCGTGGAGGAAATAGAAAAACACAGCAAGTCCTTCTATATCCGTGCTAACCGCTGCAGTTCGATCTACAATGACACCTTTGCTCTCAAAGGCTGGAAAACAGAGGAAATCAATAGCATTGAGTTTGAATTGAACTCTATCCTTGTTGAGAAGTGGAAGGGTAAAGCATACCGACTTGTGATTCAAAGACAGAAACGGATGGATGGTATGCAGGATTTTTGGGAATTATTGCTGTCCGATAAAACCTCCATATACTGCAATATCCTCTCTCAATCCTGCTGAAATAGGCATGATTAGTTCTAATTTCAAATTCCAAGCCCCCTAGAATAATGACAACTCTTCTGGTGGGGCTTTTACTTGGGTAATCAATCTATCCCAGTCTCTATGTGGCTGCTCAAAGAAACTTTGTATTGCGACATAACTCATAAGTAAAATTCTTATCATTGTTGCCAAGCCTGAGAAGCTCCAAGGTCTCTTTATTTTGTTCTTCACTAGGGTTATAAGCAGATTGGCTATAAGCGTAATCCATATTTGTATTTTTATAGCATTCGCACTCTCTCCATAGAAGTATCTTAGCGGGAAATTCTGTTTTATTTGTTTAAATAAGGTTTCTATTTGCCATCGTCTCTTATAGATAGCTATAATATCTTCTGCCGACATCTGAAAATCATTGGTCAGCAGTGATATGAATCTGATTTTCCCTTTCTTGGTCTTATCCTGATATGTGATTTTTCTTGCTTTATGGTAAATATCTTTTTCCTTTGTATGCTTATGGAAGAGAATGGTTTCTACGCGTACAACTCCATAATCTGTAGTCATCTGGTAATCCGTATCAGCAATCCTTTCAAAGCTAAGATTATTTTTCATCTTAGTTACATATATAACGCCTCTTTGAGTCAGTTCAGAGAACTTTTCATAGTTTATATAGGCTCTGTCAAAAGCAATCAGTTCCTCATTGGCGTATCGTTCTGGGATAAGTGCAAATTGATCATGACTAGCTGCAGATGTGAACTTGATATCGCTTGGAACATTCTCATTGGCAAATATCTCTGTATGTACTTTTATTCCACCCTTCTTCTTACCAGTTTTGGGATTACGTCCTACTCCTTTAAAGACCAGGTTAGAAAACAGACTGATTGTCGTAGAATCTATTATCTTTAGATTCTTCAGCCATTTGGGCTGTCCACAATTTCGGCTGTCCGAGTAAAGTTCATGGCGATATTTCTCATATAAGTTCATATAGATCGAACCGAATATCTCGGAATCTCGGCGTTTGTTTGCATCTGACAAGGTACTTCGACAAGGAAAATGCTTTAAACCAAGATGATTAAAGCGATTAACATTAGCAAAGAGAGAGGCCTTTATCTCACGCAGAGAGTCTAAACGCATCATTACTGCATAAAGCATGACGACAAGATGATGCCATGCATCAAACTTCTTTATATAGTGTTCACCTCCCTGAGCTTGGCTCAGAGAGAGAATTTTATCACGATTAAAATAGTTTAACAGTTGAACATATAGTGGCTGTCCGATAAAATGTGTACTTTTGTTCATCTTATTTCATTGTTTTATTTTGACAACTACAAAGGAAATAAGAAGGGCTGAATGTGCAAAACAATCAGCCCGTTTTTTTTATTATTCTGAATTAAAAAGATATGAACGCAAAAAAAGTTTTATCGGACACCAATATTTGGGAATAATGCTGCGTATTGCCTCAAGTCACATTGTGGGGTAAGGGGATATTGTAGGCAGAAGTGGGTGTTTCAATTTCAAATTATCTGCAAATTCAGTAATGAGAGGATGTGTAAATGCAATAAGGATGTTGAAAGGCTTAGTTGCGGATTTGAGGTACTATAAATTTGATAATAGGTTTTGCTTTTATAGACATTGTGTTTACAACTCATAGTATCACCATATAATAAGGTATAAAGCTAAGATTTTTAGTAATAAGAATATCTGTTAAAACAAAAAGACAGACTCTACTAAATCAGAGAGCCTGTCTTTATCTATATCGGAAAATAGTGTAATTCTATTAGAATGGTAAGTCATCTGTAGAATTTTCCTCTGGCTGTGCAGGAGGGAATGGAGTAGCCTGTGGCGCAGCAGGAGCTGGCTGAGGAGTGACTGGAGCGGCAGCAACAGGCGTACCAGCCATAGCAGCTGTAGCGTCTACACGCTGAACGTTCCATGCACGAATATTGTTAAACCAACGGCCGTTGTACTCATGTGCATCAATGTCAAAACTTACATTGAGTTCATCACCAGCCTTAATAGCGAATTGCTCAATTCTATCAGCACCAAAAACATTGAAAACCATCTTCTTTGGGTACTGGTCGTGTGTCTCAATCACATACTCCTGTGACTTCCATGGTCCTCGAGCTGAAGTTCCCTCACGTGCAGGAAGAACAGCAATTACTTTTCCTTGTAAATCCATTTATCTTACTTGTTTTGGTTATTTTAATACTTTATTCTGTTTGCGAAATTACTAAAATAGTTCTAAAAAGCGAAACTTTTATACTTAATTTTTGTTTTTCACGTCCCTTTTTTGTATTTTTGTACGATGAAGTTGAAAGATGGTAATGGACTTGTTTCAGCCGTCTGGATATATAATAAGTGTAACAGAATATTAACTAAAATAAGATACTAATGAGATTTAACCTTTCAAGCACTGCATTGAGCAGCCGGTTGTTGACTCTCTCTCGAGTAATTAATAGTAAGAATTCTCTGCCTATCTTGGATTGCTTCTTGTTTGAAGTTCATGATGGTCAACTTACAATTACTGCTTCAGATAGTGAGAATGTCATGCGCGGAACATTGAATCTTGAGAGTTGTGAAGGCGAGGGCAATTTTGCAGTGAACAATCATACGATTCTTGATGCTGTGAAAGAACTCCCAGAGCAACCATTGACATTGGATGTTAATCTGGATGAAATGAAGATTTATGTTACCTATCAGAATGGTTCTTATAACTTCCCGATTCTTGGTGCAGATGAGTATCCAAAGGCGCAGTCTGTATCAGATAATGCAACGACAATTACGCTTCAAGCTGAGAAGTTATCAGATAGTCTGACACGTTCACTCTTTGCAACAGCACAGGATGAGCTCCGCCCAGTGATGAATGGTGTTTATTTCGATTTGAAGGAAGATGGGTTAGCAATAGTTGCCAGTGATGGTCATAAGCTTGTAAGAAACAAGATCTTCTCTATTAAGAGTGATTCTCCTGCATCATTTGTCCTTCCAAAGAAGCCAGCTTCATTGTTGAAGAATGTTCTTTCAAAGGATGGTGGCGATGTTATCATTCGTTTCGATGAGCGTTCTGCAGAGATTTCTTTTGCTGAAGGCAACCTCGCATGTCGTTTGATAGAAGGTAAATATCCTAATTATAACAGTGTAATCCCACAGGATAATCCTAATCAGGTTACGATTGATCGTAAGTCATTGATTGGTGCTTTGCGTCGTGTATTACCTTTTGCAAGTGATTCTTCACAGTTGATTCGTTTCCATGTGTCAGCAGGTTTGTTAGAGTTGAATGCTGAAGATATTGATTTTGCAACAAGTGCAAAGGAGAGTGTTACCTGTGAGTATGGTGGCAACCCTATGAGCATTGGCTTCAAGGGCTCAAGCATGCTTGACATATTGAACAACCTGGAAAGTGATGATGTTGTCATTCAGTTGGCTGATCCATCACGTGCTGGTGTAATCGTGCCAGGTACTCAGCCAGAGAATGAGGATATTCTCATGCTGATTATGCCGATGCTGTTGAACGATTAAGAAACAAGTGAAATAGATTTTATCGGGAGGATGGCTGTGTATCTTCTATATAGCCATTCTCCTTTATGATTATATATAGGGTTATACACAGACGTATGAAACTGAATTTGACAAAGCCTTTGATAGTTTTCGACTTGGAAACGACTGGGCTTGACCTTGTAAACGACCGTATTATCCAAATTTCTTTTATCAAGGTTCATCCTGATGGAAAGGAAGAAAGAGAAAATATATTTATTAATCCTGAAAAGCCAATACCTGCAGAAGTAACGCTATTGACTGGTATTTCTGATGCTGATGTGGCTGATGCGCCAACCTTCAAGCAGAAGGCTAAGGATTTATCAGATAAGTTTGCTGGTTGTGACTTTGCTGGGTACAATTCTAATCGTTTTGATGTGCCAATGTTGGCAGAAGAGTTTCTGCGTGCAGGTGTTGACTTTGATTTCTCAAAGTGTCGTCTGATTGATGCACAGAATATCTATCATAAGATGGAGCGTCGTAATCTTGCTGCTGCCTATAAGTTCTACTGTGGTAGGAAGATGGAGGACGACTTTGAAGCACATAAGGCGGATCAGGATACTGAAGCTACATGGCGTGTGCTACAGGGTGAACTTGATATGTATGCTCCCGGCAATCAGGAAGAAGAGGATCGTGTGTTGAATAACGACATGGATGAACTTGCAGAGTTCTCTCGTATGAATGACTTTGTAGACTTCGCTGGTCGTATAGTATGGCGTGACATGACTGATAAGGATGGTAACCAATTGTTGGATGCTACAGGAAAGCCACGCCGTCATGAAGTATTCAACTTTGGTAAGTATAAAGGTTGGGATGTTGCAGAGGTTCTGCGTAAAGATCCAGGTTATTACAGTTGGATGCTTGCAAGTGATTTTACTTATAATACAAAGCAGGTATTGACACGTATTCGCCTGAGAGAGTTTAATAATAAGTAAGGTAATGCTGAAAGGAAAGAAAATAGTTTTAGGCATAACAGGCTCTATTGCAGCATATAAGAGTTGTCTTATTATCCGTGAGCTGATAAAGAGTGGGGCAGAAGTGCAGGTGGTTATTACGCCTGCTGGTAAGGAGTTTATTACTCCTATCACATTGTCTGCATTAACACATAAACCTGTTGTAAGTGAGTTTTTCTCACAAAAGGATGGTATGTGGAACTCTCATGTAGACCTCGGACTATGGGCGGATGCAATGGTTATTGCTCCTTGTACAGCTGCTACGCTGGGTAAGATGGCAAATGGAGTAGCTGACAATATGCTTATTACTACTTATCTTTCAATGAAAGCACCTGTCTTCATTGCGCCTGCAATGGACTTAGATATGTATAAGCACCCATCAACACAGAAGAATATTGAGACGTTACGTAGCTTCGGGAATCATATTATTGAGCCAGGTAGCGGTTTTCTTGCCAGTGGTTTGGAGGGTAAGGGAAGAATGGAAGAACCAGAGAATATTGTTAAGGCTTTGGCGGATTTCTTCTCTACTTCATCGGAGTCGCCATCTTATACAGAAGATTTAAAAGATAAAAAGATTCTTATAACAGCTGGTCCTACATACGAAAAGATTGACCCAGTACGTTTTATAGGAAACTATTCATCTGGTAAAATGGGGTTTGCTTTGGCAGAAGAGTGCAGTCGACGTGGTGCAAAGGTTGTGCTTGTTGCTGGTCCAGTGAGCCTTACTTGCTCTGATTGTATTCAGCGAGTTGATGTTGAAAGTTGTAGGGAGATGTATGAAGCTGCAGTAGGGGAGTTCCCTAATTGTGATGCAGTAATCCTTTGTGCAGCTGTTGCTGACTTCCGTCCAGAGACGATTGCTGAGCAAAAGATTAAGCGAGTGGGTGATGAACTACTCTTAAAACTGAAGCCAACACAGGATATTGCTGCAACTATCGGTAGTATGAAAGGAGAAGGACAACGCATTGTTGCTTTTGCATTAGAAACAAATGAAGAAGAAAGCAATGCCCAAAGAAAGTTGGAAAAGAAAAATGCTGACTTCATTGTTTTGAACTCAACGAGAATTCCTGGTACGACTTTCCAAGCAGATGATAACCAAATAACGATTATCAACAAAGAAGGTAAGAAGAGTTATGCTAAGAAACCAAAGACAGAAGTGGCTCGTGATATTATTGACGAGCTTGTTTCTATTCTCTAATGGAGAATTATCTGCACAAGAGCTAAATGCAAAGGTAACCGTGAATCATAATCAGATTCAGGGTACAGATGCTTCTGTCTTTGAGAATCTACAACAGACTTTAGAACAGTTTATTAATACACGGCAATGGACTCATTATCAGTTTCAAAGAAATGAACGTATAAACTGCAACTTTAATATTACTGTTAGCAAATATGACCCAGGTAGCAACCTCTTTACTTGTTCTGCTTTGATACAAGCAAACCGCCCAGTTTATAATGCTGCTTATAGTTCTACACTCTATAATAATCAAGATGGTGACTTTAACTTCACCTTTGCTCAATTCGATCAGATTGAGTTTAATGAGGAGAATATAGATAACCAACTAACGGCTCTGATAGCTTACTATGCTTATCTTATCATAGGGTTAGATTTGGATTCTTTCTCTCCTATGGGTGGTGAAGATATCTTACAACGCTGCATGGTTTTGACGAATAATGCACAGAATCTTAACTTTACGGGATGGAAAGCTTTTGATAATTCACGCAACCGCTTTGCTATTATCAACGATTATCTTGATGGTGCTATGAAACCTTTTCGTCAATTGCAGTACGACTATTACCGAACAGGTTTGGATGAAATGGCTAACAATGTAGAACGTGGTCGTACAAATATCACATCAGCTTTGGAGAATGGATTAAAGAAGGCACATGAGAATCGTCCAATAAGCATGTTACCACAAATATGGACAGACTATAAGAAGGACGAGTTGGCTAATATATATAAAGGCAAAGGAACACAAAAAGAAAAGGAATTGGTCTACGATATCCTCTTTAGTATCAATGCCAGTCAGAATATTACATGGGATAAAATAAAACAATAGTAATCTTTTTGTAGGAAACAGTTATCCTCTGCCTTAACTTCAATTATTATAATTGACAAATATATGCTGAAACATCTATATATTAAAAACTACACGTTGATTGATCAACTGGATATTGCTTTTCATTCTGGTTTCTCGGTTATTACTGGTGAAACGGGAGCGGGAAAGAGTATTATCCTGGGGGCAATCGGTTTGTTATTGGGCAATAGGGCTGATAGCAAACAGATAAAGCAAGGAGAAAAGAAATGTACGATTGAGGCACATTTTGACCTTTCTAACTATGGGTTTGAATCCTTCTTCGAGGAACAAGATGTTGATTTTGAACCTGAAGATACAATTGTTCGCCGTGAACTAACGGCTACAGGAAAGTCACGTGCCTTTATCAATGATACACCTGTATCGTTACAAATGATGCGTGTATTGGGTGAACAACTTATAGATATTCATTCACAGCATCAGAATCTTTTGTTACAGAAGGATGACTTCCAGTTGAATGTTGTGGATATTATCGCTCAAGACACAAAAGAACTGGCTGCTTATCGTTCGGCATACCAAGACTATAAAGAAACAGAAAGGCGTCTTTCTGACATGAGAGAGCAGATCTCTAAAGCACAGGAAAATGAAGAATTCATGCGTTTTCAGTTCAATGAGTTAGACAATGCTAATCTAATTGAAGGCAGACAAGAAGAACTTGAGCAAGAAAGTGAAACGCTCTCTCATTCAGAAGATATCAAAACAGCTTTCTACGAGGCTGATAATCTGTTGAGTGATGATGACAACGGAGTTCTTCGAAAGCTGGGACAAAGTCTGGATAGTCTTGGAAATATAGAGAAAGTATATCCTAAAGCACAAGAACTCATACAGCGTTTGTCATCAGTACATATAGAACTGAAAGATATTGCAGGTGAGATTGGTAGTGAAGTTGAGAATATCGACTTTGACCCCTCTCGTCTGGATAGCATAAACCAGCAACTTGACTTGCTGAATACACTTGAACAGAAGTATCATGTTTCCACAGAGAAAGAACTCATCGAGATACGTGATAACATTGCTAATCAGCTAAAGAATATTGATAATAGTGATGAAGAACAGGAAATACTTGAGCAAGAAGTAAAGACAAAACTTTCTACTTGTGAAAAGCAAGCAGAAAAGTTGACTACACTTAGACGTAAGGCTGCAAAGATTGTTGAGGAACAGATGAGTAGTCGACTTATTCCTTTGGGTATTCCGAATGTTAGGTTTAAGGTTGATTTGTCCCCAAAGCCTTTGACAATGGACGGTGCAGATAAGATTCAATTTCTTTTCTCTGCCAATACAAGTACGGCTATGGAACCTGTTGCACAGGTAGCTTCTGGTGGTGAGATTGCTCGTGTAATGTTATCGTTAAAGGCTATGGTAAGTGGTGCCGTGAAGTTACCAACAATCATCTTTGACGAGATTGATACGGGTGTTAGTGGTAAAATTGCTCAGAAGATGGCACTCATCATGCAAGAAATGGGTAATAATAATCGTCAAGTTATCTCTATCACACACCTTCCACAGATTGCTGCTTTGGGTACTTCACACTATAAAGTAGAGAAGGAGGAGACTGCAGAAGGGACACGCAGTCACATGCGTGAGTTGACTCAAGAGCAGCGTGTGAATGAGATAGCACAGATGCTTTCGGGTGCCGATGTTTCTGATGCAGCTTTACAGAATGCTCGAGAACTATTAGATTTAAGTAAGAAGAAATAGTAATACCTTACTAAAAATATACAATGAAAGAAATAATGAATATGAAACTGAAAACTTTAATTTTGACCATTGCCCTCATATTGGGTGCTTCTACTAACATTTTTGCTCAACCTGGTGCCGTTAAGAAGGCTGCAGATGCAGCTTTTACATTGACAACCTTTAAGGCAGATGGAAGTATATTAGCAACATCTAATGGTGTATGTATTAGTACTGATGGTGATGGTGTTGCTGTAAGCCCTTGGAAACCCTTTATAGGAGCAGATAAAGCTGTTATTGTTGATGCTAAAGGACAGAAACACGAGGTGGAGTGCCTGCTTGGGGCCAATGAGATTTATGATATAGTCAAGTTTCAAGTGAGCGGTAAGACTATTGCTGCTCCTTTGGCAACAACAGTTTCTGTAGGTGATGAAGCATGGATTACACCAATGCCAAAGAGTGGTAATGCTGAGAAGGCTGATGTTTCAAGTGTTGAAAAATTCATGGATAAGTATAATTATACGATTCTGAAATCTTCAGCTACTGACAAGTTGAATGGTGCTCCTGTATTTAATGTTAAAGGACAGGTTATCGGTTTGTTCAATTCTGCTGGTGAATCACAGAGTTCAACGGATGTAAACTATGCCAAGGACTTTGTTGTTAAGGGACTTTCACAGAATGATATCACTCTTCGACAGAGCAATATTCGAATAGGTTTACCAAACACAGTAGAGGAGGCTGTTGTTGCATTGATGCTCTCTTCTGAGAAACCTACTAATATACACGAAGCTATTGTCAACGAATTTATTACAAAATTCCCACAAGCAAATGATGGTTATTATGCTTTAGCGAATATACAAGTTGCAAAAGGTGACTTTGCTAATGCGGATAAAACAATGCAAACAGCTATTAGTAAGGTGACTGCAAAGGATGAAGCACATTATAACTTTGCTCGTCTTATTTATCGTAATGCGCTTATTCCAGAGTTTGCAGAAAAGACAAAGTCTGTGGGATGGACATTGGATAAGGCTTTGGATGAGATCAAAAAGGCTGAAACTACTAAGGCAAACGATGCTTATCGTCACCTTCAGGCACAGATTATCTATGCGAAAGGCGATTATGCAAAAGCTTATACTGAGTTTGAAGCATTGACAAAGACTAAGTTTAATAATCCAGAACTTTACTTAGAGATGGCACAGAGTCGTCAGCATTTGGGAGCTAATGATCAGGAGATTCTCGATTTGCTTAATAAGAGTATCGAACTTTGCGACACACCATATGTTTCTACTTCTGCACCATATTTCTATACACGTGGTCAGCAATTAGAGAAGATGGGAGAATATAGAAAGGCTGTACAGGATTATTATACATATGAATATTTTAACCAAGGACGTCTTGGTGCTGCTTTCTATTATATGCGTGAACAGTGCGAGGTGAAAGGACGTATGTGGCAGCAAGCTTTGCAGGATATTCTTATTGCATCACAACTTGATCCTAAGGAAGCCTTATACCCAACAGAAGCAGGTAGCCTTTTGTTACGTCTAAACAAAGTTGATGCTGCTATCAGTGCTGCTCAACAGGCAATTCAACTTGACGGCTCTCAGCCTGATGCCCATCTTATTCTTGGTATTGCACAATGTGAAAGTAAACAGAAGGAAGAAGGTCTTAAGAATATTCAAAAGGCTAAGGAACTTGGCAATACACAAGCTGATACTTTCTTGCAGAAGTATAAATAAATTTACCAGATAAGTTTATTGTCACGAAATTTGGGGGAATGGAATTTGGTAGAATCGAATTAAATCTGTACCTTTGCACCCACATGATGGTTCCGTAGCTCAGTTGGATTAGAGCAACAGCCTTCTAAGCTGTGGGTCTTGGGTTCGAACCCCAACGGAATCACTGAATGTTATAAGAGGAATATTCGTAAGGATATTCCTCTTATTGTTTTGATTATCAGTGTATTATATCGCAATGAGCTAAGGGGTTAATATTGTTAATGATAGAAATTTGTTTCATTAATCTTGCGTTTTCCGACTGATAGTTACTTTTATTTACCGATATATAACGTACTTTAATTATCCCGTGCACCCATAGTGATACCACTTGTGATACCACTTTTTTATTAATTGTGTGATACCAAAATAACGATTGCTGTATTGATGCTGTCTGATAAACATCTCTTATAAGGATTAGGCATTTGTATCATAATATGTTCATTATAACTCCATTATATCCCTTTCTCACTATCTTTAGTCTAAGTGCTTATCCTTAACACATGTCGTGCTAAGGGTAAGCACCAATGGTGTTAAGTACTTTTTAGGTTCTTATAGATGTCTTTTCCTAAAGAATTACTTCTCCATTTCCATTGAGTTTCTTAATCGATAAACTTATAGAAATTATACATTAGTCTTACTCTTGACAAGGGAATATGTTGTTAGAGTAAAATATTACTTTATGATAAAGCTTTATACTGAGCACTGTTATAGATACAATCTCGATTTACAACTCAATTTAATCGTTGCTTGTATTAAAACTTAAATATCTGTTATATATTGTTTTTATATTTGTTGTAATGAAAATATATTTCTAATTTTGTCATTATTAAAAACAACAGATTGTGAATCATCCTCTTCTTTTCAAGAGCAAGACTGTTTAACAGCCGTACAGAGGGGACTTCAAGAAGTTGTTGAGGTTTTCTCTTTTTTGTTTTCTGGTTAAGGAGATGATAAGGGTGCCTCGTTTATCATTTTTTTTCTAACAACTTAAAAAATTATCAATTATGAGTTCATTTAGAGCAACTTTGGAATTAGGTGGTAAGGAGTATGACGTACTCTATTCTAACTACGAGTTCAGCCGTACAACTGACAAGAAGGGTCAGCCTGCATCAAGCATCTCTGGCGGTCGTATCAGTGTAACTATCGAGTCAACTGATGACACTTCTACTATCGAGGCTATGCTTAACAGCCAGTTCAAGCCTGTTGAGGGTAAGATCGTTTACAAGAAGAGCGAAGAGGATGCTAAGATGAAGGAGATTTCTTTCAAGAATGCTTACATCGTTCATTACAAGGAGACACTCGACGTTAACAACGAGGCTCCTATGACCATCGCTATGACTTTCTCTGCTGAGAATATCACCGTGGGTAATGCAGAGCTTGACAACCGTTGGCCTCGCACATAAGTTTAGGAAACATTTGGACTATGCTGAGCTTTCGTACTTGGCATAGTCCTTTTTCGTTTCTTACTCAAGTGAGGGGGAACTTTACTATCCTACATACTCCGATTGCTTTCCCTTGAGATTCTAAATGTAATGCCGTATAAGCCAATTAGCTTTTAATCTTCAAAACAAACAACCCATGTCAATTCCTTTCAACCCCATTACTATCAGCGTAGGAAAGAAGTCTCTTTCTTCTTTTATTTCTCTACAAATCGAACAAAACATAGGTAAACACCACCGATTCCAAATGTCTGTTGAATTGGAAACGGGTAGTAATAGATATGTACATAATATCAATAGCAGCAAGGAATGGCTCGGAGAAAGCATCGTTGTGAAGGCTGCAAATACTCCTATCTTTGTTGGTGTGGTGACAAATGTACAATTACACAGAGAAGGAAGTGACTTTGGATGTATCATCGTTTCTGGCTACTCTGCTACTTACAGACTGGAAACGGCACATAGCTGCTTCTCATGGAATGATAGAACCATTGGGGATGTAGTGAAAAAGCTGTGCGAACAAGCTAAGGTGCAATTAGAGTTGAATCCTGCATTCAAGGAAACCAAAGACTTTATCTGCCAGTATGAAGAGTCGGATTTCGACTTTATCCGTCGTCTTGCTCATCAGTATCAAGAGTGGATGTATTTCGATGGAACTAAACTCATCTTTGGTAAACCAAGGAAATTGGCTGACCCTATAAGATTAGAATATGGAACAACACTGTCTTCACTTGACATTGGTTTACAGACCCTCGCACGCTCTGAGGAGGTATTCTCTTACCACTCTGGTGCTGACCATGAGATGCAGCGTATGACACCAGACTTGGCCTATGGTCATGACAAACTTGCGGGCGATGCTTTCCGTGCATCATTAGGTATGTTCTCAAAACCCGCACGACAGCATGCACTGCCACGTATCAGCGATGAGTCGGAACTTATTAATTACATGGGGCGTAAGCAGGCGGCTGAGACGGCAGAAACACATTACATCACGGCTGAGAGTCAGGTGCCTACCCTGCGTGTCGGTTCTGTCGTAAGTCTCTACAGCTCATTCTTGGAACGTGTAGGAAACATATCAAAAGAGAGTTTGGGTAACTTTATCATTATCGAGATAACCCATGAGGTGAGCCAAGGCAGCTACTACAAAAACCGCTTCAAGGCTATCCCTGCAACAATAAAGGCACTGCCAAGTCCAAAGGTACGTATGCCATTAGCAGAGACACAGATGGCAACCGTGCTTAGTAATGCTGACCCACAGGGCAAGGGTCGTGTGCGCGTACGAATGAACTGGCAGACGGATGGTATGCAGACAGGCTGGGTGCGTGTAATGACACCAGATGGCGGTAGTAGTAAGGACGTAAAGAGCAACCGTGGTTTTGTATTTATCCCAGAGGTAGGCGACCAAGTCCTCCTCGGCTTCCGTCATGGAGACCCTGCAAGACCATACGTTATGGGTAGTCTCTTTAACGGAACAACAGGTGGTGGCGGTGGTCAGGGTAACAACTGCAAGAGCCTTACCACTCGAAGCGGTAGTTCCTTGAAACTTGATGATTCCAAAGGAAGTGTTACATTAGCTGATCCTGGGAAAACAAGCATTCACATGGACGGTGCTGGTAATGCCACATTTGATTCGTCTGACAAAATAATCATCTCCTGTGGTAGTGCTTCCATTGAGTTACACAATGATGGTACAATAAAGATAAACGGTAAGGAGATATCAGTTGGAGGCACGGATGTCTCCATAGCAGGTACATCAAGTATTGTAGCTGGCGTGGGGGAAGGTGAGACTCCAAGTACTGGTATTGGTATGTCAACAACAGAACTTAATATAAGTTCTTCGAAAACATATATTGATGGATCCAGTGAAACTAGTGTAAGTTCAAGTGGTGGAACAACCTCTGTTACTGCATCAAGTGAGGTGATTGTAGGCGGAAGCAAAGTAAAACTAAACTAATAGTGGTATGAATCCAGTACGATTGGAATTACTAAAGATAGACAGACAATGGTATGAGCAAGTAAAAGCACATACCGATAAACCACTATTTGTATGCTTAGGCGAGAAGCACACTCTAAACATGTTTGATGTTTATTTTAAGAGTCATGGTGCAGATGAGGTAGAAAGTGACGACGTTTTCCTTGTGAATTATAAACCATTTGAGGATGCACAGCGGTATGGCGCAGAGCTATTAGAAGAACTACATTTGGTTTATAACTTGTGGAGAGAACATAATCTGATTTCTGTTCCATGTAAAGAATGGAATACGGACATTGTCGTTCCTAATGATAAAGTAAAGACTGATGCAGGGAATACAGCTAAGGCGCTAATAGGACTATATGAATCTTTTCCACCACTACGTGGACACAAGATATTTATTCTCTTATCACCACAACAGATAAGTAGTATACCTTTATATGAACAGTGGCTGTTTGATTGGTGTGCTAATATGAATAGCAGTGATGTCAAGATTGTAGTTCTTGAAAAACATGAAGGTCGGCTGTTAAAGAATCTGCCTGAAAACAGACATGAATTTGTACTTACTGGTACTGACATTGCTTCTTTGATGAACAATGTGGCTGCCCAGACTGCTGCAGATCCTAATGATGAAGAAAATGTCCTGCAACAACAAATGTTATTGGCAAACGTTCACTTTAGCAGGCACGAGTTTGATAATGCTCATGTTGCTTTGGCTAAAGCTATTGGCATAGCCAGCCGACACAATCTTAAAGACGTGCTATGTACGGCTCACCTCTTAGATGCTTATGTATGGCTTACACAAAATGAACAGGAGAAAGCACATGACACATTCCGTACTTTATTGAGTCTTACTGGTGAAGGTACTTTATTGTCCGCTCAGATGCATGTGAATTATGGTGGTTTCTTGCTTGCTATACGAAGAAAGGAGGATGCAATAGATGCGTTTGAGAAATCAGCTGAGATTGCAAAGAATATAAAGAATCCATTATTGGAGATGGAGTGTTATCGTATTATGGGTCAAATACAAGATGGTACATTTACAGATTCACAAACCATTGCTTATTATGAGAAGTGTATAGAGATAGGTATGACTATGAACAATGAGGAAAGACAACAAAGTTCATTAGCTTACATAGCTACTCTATTACTAAAGAAATATGGAAACTCTAAAAAGACAGAAGAACTTTGTAAACAAATGGAGCAATATTTAGGTGCAGATTGGCAAACTAACATACAAGTCCCCAACATGGATGACCTATATCATTCACCCTTAACAAGTGTATCCTCATGAAGATAATAGCAAAGAAAGCCAATGTAGCGAGTACTGCCGTACAGCATGTGGCCAAACATTTTGATTTGGTATTAGGCATAGACATTCACTGGACAAAGCTACCTATGCCTCCTTTTCCTCTTCCCTTACCACACCCTTTCATAGGAATTGTCTTTGACCCCATGGAGTATGCAGACTTCAGCATACCAGTCCCTTCCTTGTTGCAAAAGATGTTCAATCTCCCAGAGAAGATCCCTATGGGAGCATCAGTGTTTGTTCATGGCCGTATTAAGGCAACAACTACTACATCTGTCTTTGGATTTGGTTGTAATATAAAACCTAAAGGTGGTGCTGCAAGTATGTTAGGAGCAGCTATGGTTGGGAATATTATACCTATCAAACATATAACAGGTGGTCTACCTTTCTATAAAATCTTCTTAGGAGACTTGGAAGGTCCGCATGATGGTGAAATCTATTTTGGTTCGGAAAGTGTCATTATCAATGGTAGTGAGTGCAGTGGATCATTCCCTCAGCAGGTTCTAACTTGTTGGGGCATACCTTTCGGACACCAATATTTTCCTCCGGCATGGCTTGCTCTCTACCAGCATATATTAACAATGTATGTGCAAATAAATATCAAGCCACCTGTGCTGGTGGGTGGAACTTTTATCCCTCATAAGTACACACTCTCTGACATTTTGATGCGTGCAGCAGCTGTACTCTTCATGAAAGCACTGGGAGCTATTGCCAAAAAAGGATTGACCAAATTTAATCATTTCCTTCAGGGTAAATTCGGTAAGAACCCTATATCTAAATCATTGTGTTTCTTCGGTTTGGAACCAGTGAACTTTGCTACAGGAGCAATGAATTTCTCTTGGGACGACTTTGAGCTATTGGGAGAGCATACCATTCGTTGGACAAGTGCGTGGCAGAGTGACATTACCTATTCTGGAATCATGGGTAATGGAGTGATATGTAACTATGACCTGTTCATTATTCCTCAGGATGCAGATGGGGTAGCAGCTTACAATAATCCAAATGAGAATCAAGTATTCCCAATACCAATACCAGAAATAGGAGGCAAAGAGGAGTATTATCGTTCTCTAAAGTTATGGCAGCATAGACCAAACAAATCTAAATGGATTGTAAGAACAGAGACTGAAATCCGCACCTATCGTGCCTTCTCTGACAAGGAGTATGGTACAATATATCTTGCTGAAAGGATAGACTATGTGGGAGGTGGTTTCCTATTGTTAGATTATAGTGGGCGTAAGCACTTGCTTTCTACTATAGAAGATCACCTTGGACGTCTTATAATCTTTGGACAGGATGAGGAACGAGGTCTTATCCGTTCAGCAATGTATAAACATGGCGATGTCATAGACCAATTGGTGGCATACGATTATGATGAAAGGAGTAATCTTATACGTGTACGTGATCGATTTGGTAAGAGTATTGAGTTTGAATATGATGATGCTAATAGAGTGGTTCTACGTCGTAACCGCAACAATATGACGTATACATGGGAGTATGACGCTGAAGGACGTGTTATCCATACTACTGGTGAAGGTGGTATACAGGAAGGATATATATCTTACCATGACGGATATAACGAAGTAAAATACTCTGCCACAGGGGCTACGGAACAGTATTATTATGACGAAAACAACCTTGTATATAAAAAGGTGGATGCCATGGGTGGTGAGACCTGGTATGGTTATAATTCTTGGCATGAGCGAACATTGGTAGGTACACCAGAGGGTAAGGTCGTAGGATATGATTATGATGACCGTGGTAACCTTATAAGATTGACGGCTGCTGACAGAGCTGAGACTGTTTATGAGTATGATGAGCATAATCGCCTAATAGCACGTACGGATGCTGCTGGTAATAGAGAAGAATGGGTCTATGATAAAGAGACAGCATTGTTGCTGAAACATAAGGAAGCGGATGGTACTGTTGTTACTTATACATACGAGAAGGATAAGCAGCAGCCTTCTGCTATTGAGTATGGTGAAGAACTACGTGCTGTTCTACAATATGACACTTTAGGATTAATCTCAAATATTACGGACGGGCATGGCGTTTGTGAAACATTCGCTTACGATGACTATGGCCGTCCACTGAAGCACAGGCATGCTGACGGGAATAGTACAGAATGGCAGCGTGACCGACTTGGCCGTGTTACTCGCTACGCAACTCCTGGACAGAGCGTGATGCGCATCTCCTACGATGCCTACGACCTGCCTGTTGAAGTTACCAGCGGCAATGAAGTGTGGACTATGGAGTACACTCCTATGGGTAACCTGCGCCGTCAGACACGACGGACGAGCAGTATGCGCATGGTCAGTGCGCTGAACTATGAGTATGATTCCTATGACCAACTGAAGTTTGTCGAGAACGAACACGGTGAACGCTACTTCTTTGAACGTAACCTTAATGGTGAGGTGATTTGTGAAAGGGGCTTTGATGGATTAGAACGTCATTATATCCGTGACCTTGACGGCACGGTGATTACTACACAGCTTCCTGATGGTACGGCTGTGCATCATCAGCATGACCAGGCTGGACGGCTTACCTATAACAAGTACACCGATGGTAGTTGGGAGGCTTGGGAGTACGATAAGGCAGGACGGCTCACCAAAGCGTACAACAGAGACAGCGTGACGGAGTTCGTGCGTAATGCTTTGGGGCAGGTTATAAAGGAAACGCAGGACGGGCGTACAGTGGAGCATAAGTATGATGAGCGTTCCCGACTATCAAATATCGTCAGTGCATTAGGAGGAAGTATTACCTACGGATATGATATAAAAGGCACTGTCAACCACATATCAGCTGGTATGTCAGGAAAGAGGAAGCCTTGGGAAGCGAATATAGCATACGATAGGTTCGGGCGTGAAACTTCACGCATAATGTCTGGTTGTGTAGAGAATACTATGCAATATGACAATGTCGGTCGTCCTGCACATCAGCGTGTCCAGCATAATGGGCGAACACTGCTTGACAAGTCATACCTCTGGGGTGACAATCTTCGTCTTCTACAGGCGCTTGACACAATAAACCGCAGAAGTGTCCGTTACGATTATGATACCTTCGGTTCTCTGTCAGGGGCTGTTTATGGTGACGGTAGTTGTCAGTGGCGTAACCCAGATGCAATGGGTAATGTGTATGATAGCCCCGACCGAACGGACAGGAGTTATGGTCGTGGTGGACAGCTGCGTGAGGACAAGAAGTGGCGGTATTATTATGACAGCCATGGCAACCTTGTGCTGAAGACCATGCGCAGGTCGGGACCATCCCTTGATGCTGGGATGCGGGATAAGTTCCTTCAATGGCAGAGCGGTGACTATGCCTATACGTGGCAGGGCAATGGTATGCTTAGAAGTGTAACACGGGCTGACGGCAAAACTGTAACGTTCAAGTATGACGCTTTAGGCAGACGCATTGAGAAGGTCTTTGACGGACGAGTATATCGCTACCTCTGGGATGGTGATGTCATTCTGCACGAGTGGGACTATGCCGAGGCTGACCGCCCGAACACGATTGTTACCGAGACTGGTGAGGTCACACTCGACAGGCCAGAACCAGTTGAGAATCTCATCACATGGGTTTACGACAGTGACAGCTATGTCCCTACAGCCAAGATTGTCGGCGACAGGCATTACAGCATCATCAGCGACTACATCGGTCGTCCTGTCCAAGCGTACGATGATAATGGTAATGTTGTCTGGCAGGCAGACTATGACATCTATGGTAATCTCCGCAATCTCCACGGCAGCAGGAAGTTCATTCCTTTCCGCCAGTTAGGACAGTATGAGGACGAGGAAACTGGGCTCTATTACAACAGATTTAGATATTATGATCCAAGGATTGGCAATTACATCAGTCAAGACCCGATAAGGCTGGCAGGAACAGGTTTTAACCTATATGCCTATTCTAAAGATAGTAATATTGATTTTGATATTCTCGGCTTAGAATGCTGGAGTACAGCAAGAAAAAAGTTTTGGCAGCAAGAGGCAAAAAATAATCCTCATTTGTACTCTTCGAATAACTTAGCAAGAATGGAAAAGGGGAAAGCCCCCAGAATGACAATACAGGTCTTGAATCCCAAGACAGGTAAGATAAGTGTGAAGGATGTTTCTATGGAGTTACATCACAAGTTTCTTCCCCAACGAGGCGGAGGTCAGGCTGCAAACAAAGCATGGAATTTGACAAAAGCAACCCCATGGGGACACGCTTCGATGGATTCCTATAGACATACTGGATATAAATTAATAAAAGTGATTAAAGGAACAAACTCTTGGTAAATATGAATAAGTTAAATGAATTTATTAACGGGGAAAAATATGAATTTCTCCTGAGGAACATACAAAAAAAAAGTAATATAGAGATTGATAGTACCATCCCTTTTGTATTGTTAGATTATGACAAAGAAATGTTAATAGCCGCACGAATTGAAATAGAAGATTTAGAATCTTTACTTAACTCATACATGACGGAAATAGTTTCTTTTGTTGAAAGAAAAATGAAATATGATTTTGAGGATGAGGATGAATATCCTGAAGGGGAAGAGCTAAGTGATGACGAAAAGCCTAAAACCATTATTGAACTACCCTACTATAAAAATTTTTTGATTGCTTATCTAATAGAGTACTATTTGCTTAAAAAGCAGCCTGCAGAATTAGGTAAATATTTAAAGAGGATACACATTTCGCATGCAACTAAATACGAAAGAGATTTGAAGGATATATGGAGAGAAACTTTGGAGAGTTGAAGCGACTTAACTGAAATAAAGGTTCTTCCGTTAAATACTTTGACTTATTTCGTATAGATTTAGCGGAGGAACCGAGGTTATGCGTTAAACAAACAGATAGCCAAGACAGTCTTGACTGTCTGTTTTATTTATCCTCCGACACAGAATACCTTACCATTTTAACGCTTCGAAAATTTGGAGATAAGACATTGAAAAGTCATGACATTATTTCGAATAAAACGTCTAAAATAAAGTGGAAAAACACGTATAAACAGCAAGATTGCAACCAACAGAAAATCAATTGGTTATGAAGTCGTACAAGAAAAGGTGCTTGGTAAGGGTTCAAAAGGGCGTTAGTAAGACCTCAAAAGGGCACCTATTGCAAGTCAATCAGGCGTCTTTTCAAAGCCAAAAGAGCATATATCGATTTTGAGTCGTATGAAAATAGTTTACAAGTATCGGTTAGTATAGGGATAAGTTGTTTGTAGAAGACAGAAAGATATGATAATGGGTAGACATAGTATTTATTATCTGGGGTGATAATCTTCGTCTTCTGCAGACGCTTGACACAATAAACCGCAGAAGTGTCCGTTACGATTATGATACCTTCGGTTCTCTGTCAGGGGCTGTATATGGTGACGGTAGTTGTCAGTGGCGTAACCCAGATGCAATGGGTAACGTGTATGATAGCCCTGACCGAACGGACAGGAGTTATGGTCGTGGTGGACAGCTGCGTGAGGACAAGAAGTGGCGGTATTATTATGACAGCCATGGCAACCTTGTGCTGAAGACCATGCGCAGGTCGGGACCATCCCTTGATGCTGGGATGCGGGATGAGTTCCTTGCTTGGCAGAGTGGTGATTATGCCTATACGTGGCAGGGCAATGGTATGCTTAGGAGTGTAACACGGACGGACGGCAAAACCGTTACTTTTAGGTATGACGCTTTAGGCAGACGTATTGAGAAGGTCTTTGACGGACGAGTATATCGCTACCTCTGGGATGGTGATGTCATCCTGCACGAGTGGGACTATGCCGAAGCTGACCGTCCTAACACGGTTGTTACCGAGACTGGTGAGGTCACACTTGACAGCCCAGAACCTGTTGAGAATCTCATCACGTGGGTTTACGACAGTGACAGCTATGTCCCTACAGCCAAGATAGTTGGTGACAGGCATTACAGCATCATCAGCGACTACATTGGTCGTCCTGTACAGGCATACGATGATAAAGGTAATGTTGTCTGGCAGGCAGACTATGATATCTATGGTAACGTCCGCAACATTCACCGCAGCAGGAACTTTATCCCCTTCCGCCAATTAGGTCAGTATGAGGACGAGGAGACTGGACTGTATTACAACAGGTTTAGGTATTACGACCCAGGTTCGGGTACTTATATCAGTCAAGACCCAATTGGGTTGTTGGGAAGTAACCCAACACTGTATGTACATGTTAAAGATGTAAATACACAAGTAGACTCCTGGGGATTATTAAATGAATTTGGGATTGCTGGATATGGAACTTCACCACATATAAAAGATGGATTAAGTGCCCACGAATTATTACAAAATGCCTGGCTAAGAAATAATGGTGTCATTACAAGTAGAGCATCAGGAATTGCAAAGAATAATCCTGCTATGGCACTACAAGAGAAAATGATGCATAAAATAATATCTAAATTACAGGCACAGTATGGATTACATAATCCAAATGTGTTAAAGAAACAAACAGCATTACAAAATATAAATAGAAACACAGCATTAACCAGAAGAGGTATTTATGAAGATCTCGTAAAAAATAGAGGTTGGGAACCTTATAATGCTAAACAATTCGCAACAGAAAAAGCTATGAAGTTGAGGGAAGAAGCTATAGAGTTTGCGAAACAAAATGGTTTAATTAAATATAATTAATTATGAACAAAGTCGCCAAAATCAGTTTAGACTCATCATCCACAGAAATAGGTAGAATAGGAGGAAATATACCGACTTGTTTTCTGGAGAAAAAGGAAAATATAGAGGGATTTAAATTTTATATGACAATTCAAAATCCTGATAATTCAGACGAATATATATCTATCTTTGTACCAGATAGCTACGATACAATGGTGGATGAAAATATTTATCCCAATTGTTCAATAAAGGTTTTTACCCATTCGTTTTCTGTAGAGAGTAGTAATAACTTTTATACATTGAAAGAGCTTCATAAATCATCCCTTATGGGATACAAAGAAGTAGAAAATGAGGAATTTGATTTTGTCACAAAAACTCAGCATCCTCAGTTAATCCAGTATGAGGATTATTATTTAAAAAAATTAGATGAAGATGGGTTCACATTCTATTTGCAAATCGATGAAGATTATTATCCGGAAAATCTTCTTTCTGGGAATTATATATTGGGGTATGGTGCACTATATTTATACAAACATAAAATCACAGGTAATATAATAGTTGGCTTTTGGCAATATTCATAATTCGTTTTAACGCTATGTGTAAAAGAATGATGTCTCCTAATAACAACACTGCCACATTTAACTACAAAACATTTAATCTGATGAGTCGAGAAGGTCTTTGACGGACGTGTGTATCGCTACCTTTGGGATGGTGATGTCATCCTGCACGAGTGGGACTATGCCAAAGCTGACCGCCCGAACACGATTGTTACCGAGACTGGTGAGGTCACACTCGATAGGCCTGAACCAGTTGAGAATCTCATCACGTGGGTTTACGACAGTGACAGCTATGTCCCTACAGCCAAGATAGTTGGTGACAGGCATTACAGTATCATCAGTGACTACATCGGTCGTCCCGTCCAAGCATACGATGACAAAGGTAATGTCGTTTGGCAGGCAGAATATGACATCTATGGCAACCTCCGTAATCTCCATGGCAGCAAGAAGTTTATTCCTTTCCGTCAGTTAGGTCAGTATGAGGAAGAGGAGACTGGTCTGTATTACAACAGGTTTAGGTATTATGACCCAAGGATTGGTAATTATATCAGCCAAGATCCGATAAGGTTGGCAGGAGGAAACCCTACGATTTACGGATACGTTAAAGATTTAAATTCGTGGGTGGATTCTTTTGGGCTAGAAAATATTATTTTTACATCTTCTGACGGATTTACTTTGGAAGTTAGAAATGTGCAAGATTTAAGTCATTTATCAAATCGTGAAATACTAGATATCTATCATGCCAATAATAATCCAAAAGGATATGGGAAATCTCCCAAACATGCAAATGGCGATACAATTATTTTGCATCATCAAAATCAAAATCATTTAGGGCCAGTGATAGAGATGCCAAATAGTGGTCATGTTCGAGGTCTTGGAAATAAAAAGATGCATCCATATTTTCCAAATCCACATCCAACTAATCCTGTAGATAGAGACGTATTCAACAATTGGAAAAAAGAATATTGGAAATACCGAGCAGAAACTGAGATTAAGAAAAGAGGTTTATCTTATAATTAAAAGTATTTTTATGAAAACAGAGTTAATTGAAAGAATAAATAGTTACTTAAACAAGTATCAATCATTCAATCCACAACCGGCAAATGATAAAGATATTAAACAAGCAGAGGTAATGTTAAATGTAGTCTTTGATTCAGATTATAAGCAATTCATAAAAACCTTTGGGGGATGCTATGTTGGGGTGGATATTTATGGAATCAGAAGTTCAAATGACTTAAAAGAGAAGACAGTTGTTGATCTAACTAAGTTATACAAAGAAGCTGGTTGGGCTATTGCAGATGATTGTTATATTATTTCATTTGATTCATCAGGCAATCCAATCATGATGAATAAATCGGGAGAGGTTGTTCTTTTTGATCATGACAACGGAGACTCTGTTATTTTAGCAAACTCTTTTGAGGAATTAATTGAAGACAATCTTCCTGATTAAAATAAGATTACAGGCGACATTGCTATTAGAGTAGGAGACTTTCGCATATACCTATCAAGATTATAACCAACGGAGAGATTTTCGTCTTCGTTTCCTACAACCTCGATATACCCTGCAGGCATTTAATAACAATGGCAAAAAGGGATGAGAGTAGGAACTTGACGCATTCGGCAGAAAGAGGAAAGGCAACAATAATTCCTCCTTCATTCCATTTAAATATTAGGGTCAGTATGAGGATGAGGAGACTGGGCTGTATTACAACAGGTTCAGGTATTACAATCCAAAGATTGGTAATTATATCAGCCAAGACCCTATAAGGTTGGCAGGAGGAAGCCCTACGCTGTATGGTTATGTTAGAGATGTTAATATAGGACAGGATATATATGGGCTTGATATCTCCTATAAAGGTGATGTTTTACCATATCAAATAAGATATAATCCAACTTGCCCAGGTCGGCCCGATCCTAGGTATTCAATTACTACTACTTTTGATGGTGGAACACCTACAGCAAAAGGAGGGTTGATAGACAATAAACAATTTTGGAAAAAATGGGAAAACTTAACCCAAGTTTAACCGGCAAAATTATTTTTCATAAATTTTCGGGATGTTTTGTGTAGTATCAATTTGATAAATGATTGATAATCAAGTATAGGGTATTGTAACGAGGAGTAAAATCTGATTTGTAGGACACAGCCATATCAAAAATATTTTGTTACTTTGCACTCATGCACGCAAATGTACAGACACGATTCAACCCTGCCACAGGCGACATGGCTCCTTATTATCGCATCAAGGAGTCATATCGTGACGTGCAGGGTCATGTACATTCGCTAATTCTGTTGAACATAGGTTTTGAACCTTCACTTACTGCTGTACAGGTTCGAAAAATTGCATACGCTCTTACCGAACGCTTCAAAACCAGAAGTACACCCTCGCTTTTCAAAGAACGCCTTGAGGGACTTACTCCTATTGAACAGGCAAAGGCTGACGAATGGTGGAGCCGTATGGAGAAAGAAGGTGGAATCGATCGGTTTAATAAGGAAGAGCAGAAGTCGCTGAGAAAATATGAGAACTACATTGACCTCGAGACGGCAAACTATACTGACGCAAGGAATGTTGGTGCAGAGTGGCTCTGCAAGCAGACGATAGACAAGCTGCAGTTAGAGGGTTTTCTGCGCAAAAACGGCTGGACGGAGAATGCGATACACACGGCTTTGTCAGCATTGATTGTTCGCACGGTATATGCAGTCTCTGAACGTTCATCTTATTATTATTTGCGCGATAACTCAGCTGCTGGCGAACTTTACAGTGGAGTTCCTGGCTGGACACCAGGGATCAATTCTCTGTATAAAATCACCGACAAGTTATATGAACTAAAGGAACAGTTAGAGCGTCATCTGTGCAGCGTTACTGACGATCTCTTTAATATAGACAACAAGTTGATGCTCTTCGACTTAACCAACTTCTATTTCGAGGGTAGTAAGCGTAATAGCGATAAAGCCAAGTTCGGTCGTTCAAAAGAAAAACGCTCTGACTGTAAGCTACTTGTACTTGCATTATGTATCAATAAAGAAGGTTTTATACGTTATTCTTCTATCTTGGAGGGTAATACAGCAGATCCCAAGTCTCTACCCAATATGATTGATACGCTGGCAAAGAGGAATCCATCACGAACCAAGGATACGCTCGTTATCATGGATGCAGGTGTTGCCACGGAAGAGAACTTGGAGTTAATAAAGAAAAAGGGTTACAATTATCTCTGCGTATCTCGTACGAAAATGAAAGACTATACGCTCAGTGATGATAACAAGAGCGTTACAGTAATGGATGCCCGTCGGCAGAAGATAACGCTGAAAGAGGTTAAGACAGAGGATGATGAGGATTATTATCTCGAAATAACATCTCCTTCGAAAGCTATGACAGAGTCGTCCATGAACAGGGTTTGGAGAGAGCGTTTTAAGATGGACCTGCAGAGGATAAACGAAGGAATCTCCAAGAAAGGTGGAACGAAAACCTATGAAAAGGTTGTTGAACGTACAGGACGTGCCATACAGAAGTACCCTTCTATAGCGAAGTTCTACCAGATAAGCTACATAAAAAATGAGAAGAAACCCAAGGAGATGCTACGTGTAGACTGGGAGATAAAAGACCTCTCGGCAATGGAATCTGGTCACGGAGTCTATTTCCTCCGCAGCAATGTCAGGACACTTTCTGAGCGTGTGACATGGGAATACTACAATCTCATTCGTGAAATAGAATGTACGAACAGACAACTAAAGAATGATCTCAACCTCCGTCCTATCTATCATCAGAAAGATGAGCGAAGCGACGCACACCTCTTCTTCGGTTTATTAGCCTACTGGGTGGTAAACACTATCCGTTGTCAATTAAAACGAGAAGGAGAATCCTGTTACTGGACCGAGATAGTACGACGTATGAGTACCCAAAAGCTCGTCACCACAAAAGGGAAGAATCCATTAGGTGAGAACACCGAGATGCGCCAATGTAGTAGTCCTTCAAAGCAAGCAAAACAGATATACGATAAGTTGAACTTAAAACACTCACCATTCAAAAAGAATAAAATTTGTAGGACACAGAGCCCATAAGAAAAATGAGGAAAGTACGGTAACAGTAACAATTAGGCGAAGCTGGGTGTTAAACTTGGGCTAAGTGTTATAAGAGGAATATTCGCAAGGATATTCCTCTTTTTATTTTGATTATCAATGTGATATAGCGTTATAAATTATATTTTTAATGGGTTAGTCCTAAAACCCAGTTGCAAGCCTATCCTCTTAAGCACACAATTTCATAAGTCTATATAAAAATATTGGTGTCCGATAAAACTTTTTTGGAGTTATCTGTGTTAGTTAAAATAGACTTAAACTTATGATTTCATTAATTTATCTGGTTATTATAGGGCTTTCCTTGTCAATATAAGCACATTTTATAATGCTTACAGTTTGAAACTGAAAACCAAGCCCCCTGGATAAGTAAAACGGCTGTAACACCGATGAGTAAAGAGATACAGAGCTTTCATTTTATTTTTACCGGACAGCAATAATATAAAAAGAAAGGAATATCTGTCACTCCTCTGAACTGTGCCCTGAATGCCTTAACTTTAGCATTGAATGACTCGGCATTTGCATTCGTAGCTCTGTTTACAAAGAAATTGAGTATGGTTTGATAATGATTTTCAAACGTGTCAATCACTGTGTAGAAATTGTCCACTCCTAATTCTTCTACCTCATTAAACCATTTTGCTAACTTCAGCCTTGCGGCATCCTTGATGCTCTTGATGTTATAAATATCGGTAAGTTTCATAGCCAAATCATACGCCTTTTTCAGTGTTGGATAATGTTCAAAGATGATTTGTGCTCTGTCTTTCTGTGTTTCAGTCCACTTACTCTTGTGCTTGGTCAATATGAACTTTGCTCTGGCGAGCAACTGCTTACGCGTGTCACCATTGCTGTATCTAAATGGTATATATTCCTTTCCCTTGCTTTTAGCTTCTTTTATCTCCTCGTTCTCTTTATCTCTTGCCATCCATCGGTAAGCAATACGCATGTCATCCAGAGCATCATAAAATAGTTTCTGTACATGAAACCTATCATTGGTAATAAGTGCTTTGGGAAAAACGGCACGGGCTATGCGCATCATAGAAGATGACAAGTCGAGTGTTATCTCCTTGACTGTCTTCCGTTTAGAAAGGTTTATCTTCTTGAGAACCTGAATAACATCCTCTGCTTTGGTCCCTTTAACCACAGCTATCAAAGTCCCTTTTCTGCCCTTTCCCGCCTTGTTGGTCAGAAAAGTATAAACCTCGCCACTGCTTAGACAGGTCTCATCGATACTTAGATTCTCACCTATGTTATCTTCAAACAATAGCCAGTCTTGAGCATGATCCAACTGATCCCAGCTACGGTAATCACTGAAATATTCCTTGTACTGTGTGGATAACAGCTTACCATTTACGCCATAGTGCGCACCGATACTTGCGATGCTCTCTGCAGTGGACTCAATTCTATTCTTTTAAAAAAGAAACGAACTCGGGGGATAATTTACTGCCCTCGGCCGTCAAGTCATCATATGAATAAGTAAATATCTCTCCGTTGGAACTGTCACGCCACTTGCGACGGCGAACATGGAGGTAAACTGCTTTGCCACGGAGGGGGAAGTCCTGAATTACACGCTCGCTGGTAAAACCATAACTGCTTACAGTGCCTAACTTATGGTCTGACTTTTCCATAAAGTTACGCTCGTCAAGCCAAAAGTCAAACTGGCAAGCACTCTCTTGAATATCGACAACATCAAAGTAGTCGGCAAGTACATCTGGAAATATGCAACGTAATAATTGGTGACTCTTCATGATGCAAAGGTAATAAATACTTATGAAATTATGCGCTTAAGAGTATAGGCTTGGAACTGGGTTTTAGGACTGCCCCATTTTTGTATGCCTAAAGGTACAAAAACTTTAGGAAATAGCAAAGCCCTGGCTTGAGAAAGTCGGGGCTTTGTGCATAAAAAAGAGGATGTGGACATTTTGACACACCCTCCTTGTTGTTCCAAGTGATTCGCATGGGGCTCGAACCCATGACCCCAACATTAAAAGTGTTGTGCTCTACCAACTGAGCTAGCGAATCTCCCTATGCTTTTATAAAGCGAGTGCAAAGGTAACAAGAATTTCTGATAATTCCAAATTATTTATAACTTTTCTTGTGCCTTTTTATTAATACATGGCTATTTGATGAAATCTTTTAGTGTGAGACATGATGATTTCCAGCAGGATAAGAGTTAACCCCAAATCGGTTATGTATAATTCTTATTACTATAGTGTTGTTTCTAAACATCTTTTATTTTCTTATCGCCATCTTGTGTGTCTTTGTAACTTGACGTAGCCCGTTACGCCTGCGTTACAACGACAGGCAATCTGCTCGATAAGAAAACAAAAACTGTTTAGGCTCTAATGACCGATTTGGGTTAAACTAACATAGCATGCGATACAATCTTAGTTAGAGTAGTTTATTTTCTGTTTATTTTATATTTGTAAAATATTTTGAGTTATCTCGTTATTAATATTTGCTCTTTTAGCATTCAATTAACGCCCAATAGGCTTTCAAAAGACGCCCTTTTGAGGTCTTACTAACGCCCTTTAAGAAGCCTATTAAGCATCTTTTGAAATGCCTTGACTTAAGTTGTTGATTCCCTGTTGGTTAGACAGATGATATTTACGTGTTTTTTTTGTCTTTATTTTAATAGGTTCATTTAGATTTATGTAAAGTCTTTTCAATGCGGTATGTATAGTTGAAGTATTTCATGATGAGATTTTCAATGTAGGCAGATGAGAGATATAAATGGATTTATGAATGATAATTACACCATTAATTAGATCATAAAATAGCATCAGATTGAGCTCTGCATGATGAAAATGTTAATACAAAAGTAATTCTGTGATTAACTCAAAAAGTTGCTTTTATAGTTGCTTTGTAAAAGATAAAATACTATATTTGTGGCGTAAGATTGATTATTTAATCTGTTACTAAACAATCTAATGTGGTATTATCCACTAATCTATTACTAATATCTAAACTATGTAGCCGATGAATGTATTAGACTATGTAAAAGCGTTCAATGAGTTTTTGTAGAATAGTTTTCTCATGTACGCATTGTTAGGAGTAGGCATTTTCTATACTGTCTACCTTGGTTTCCCACAGATTCGCCATCTAAATTTGGCGTTTAAGTATGCTTTTGGTCCAATATTCAAGAAGCGAAAGCCTGGTGAAACAAAAGTTAATTCATTCCAAGCATTAGCCACAGCTGTAGCCGCTCAAGTTGGTACTGGTAATATTGGTGGTGTGGCAACAGCTATTGCAAGTGGTGGTATGGGAGCTATTTTCTGGATGTGGGTATCTGCATTGTTAGGAATGAGCACCATTTTCTCTGAGGCAGTACTTGCCCAGAAGTATAAGAAAGAGTATCATGGCGAGACGGTTGGAGGCTCAGCCTATTATCTTTATTATGGACTTGGTAGTAAGTGGCTTGCTGTTTGTTTTTCTGTTGCTATTGTTCTTGCGTTGGGATTCGTTGGAAATATGGTACAAGCAAACTCTATTTCAATAGCTTTGAATAATGCTTTCCATATACCTTCTTATATTATAGGTGTTGTTTTAGCAGCTGTTGTGGGTGTAGTAATTATTGGAGGACAACGCCGAATCACCGCTATTGCCGAACTTTTAGTCCCTTTCATGGCGATTGTGTATATCTTGGGTTCGCTTGTTATCATTTATATGTTTGCAGATCAGTTGCCTCATGTTATCCGTACAATCTTCCAGGATGCTTTCTCTATGAAGTCAGCAGCAGGTGGAGCCGCTGGTACGGTGATGAAATATGCCATTCGCTATGGTGTTGCTCGTGGTCTGTTTTCGAATGAGGCTGGTATGGGTTCAACACCTCATGCTCACGCTTTGGCTGATGTTAAAGACCCTTCTGAGCAGGGATTTATAGCTATGGCAGGTGTTTTTGTTGATACCGTTCTTATCTGTACATCAACAGCTTTTGTCATTATGCTGACAGGTTCTTTCCAAAATCTAAGCTTAAAATCGGTTGCTATTACGCAAGAAAGTTTCGAGATAGCTTTTGGAAATGGTGGAATTATCTTCCTTGCCATCAGTCTAATCTTCTTTGCTTTCACAACAATTATTGGGTGGTATATGTTTGCTGAGATGAATATCAAGTTTATGTTTGGTAAGAAGGGCATTCTTTCTTATCGTGCACTTGTTGTTCTCTTTGTCTTTCTTGGCTGCCTCTTTGCAGCAGATATGGTATGGGAATTGGCTGATACCTTCAATGGTCTGATGGTAATTCCTAACCTTATTGGTATTATTTTCCTTGCACCTCAGGTAAAGAAAATATACAAGAACTTCTTGGCAAACAGAAAAGAAAATAATTCTTAAGCCTTTTGTCAACTTCTATTGTTATTTTCTTTTGATGTTTCTTCTTATTATGTTGAAACCAATCAATTGAAGAATAAATAGCTATTTTGAGCGGTGAGCTACATGTTGGTATGTGCTCACCGTTCTTATGAATCAGGTAAGTAGTTATATAGAGAAGTTTGGAGTAAAAGATAATAGAAGTACGAGCTTTACTGATAAAGAGAAGCAGACTTTATAGAATACGATAATACAATGCTTAATAATGATTATGTATCGATAAAGAGTCATTCCGCACATAGCGTGTTGATGCTCCGCACATATTGTGTTGTTGGTTAACACCAATTGTGTTGAGCGCTAAACATCTTGCAAAATGTCACCAAAGTAGGTTCAACTTATTGTTATAAACAAGTTGTACTACAAAGAACTTACTTAGCCTGTTGGGTTAGTAGCTTATTTCGTAAAGTTGATAAGATAGCACTTCAAGGAGATACTATTCTCTCTTTTATCCTATAAGAGTAGAATGATGCAGTTGAAATAAAATCAATGAATAACTTATATCTACTTAAACTAACCACTCTTATTTTCTTTTTTCACCCTCCACGATTGGTTTCTGTGCATTCATTTTGTGTAATTTAGATGTGAGATGTCTGTAAAGGCGAGCAACGAGTTGAGGATGCGAAGAGGCAAGGTCGTTCTTCTCAGACAGGTCGTTTGATAGATCATATAGTTCTTTTTGACCAGTGAGATACGAATAAATCAATTTCCATTGCCCTTCACGAATGGCACAATTAAGACTGATTCCCAATCCCTCTCCATCCCAAATGTTAGGATAGTTCCATATCAGTTGTCGCTTCTTATCACCTTGTTGTTTACCACGAAGAATAGGTGTAATGTCTTGTCCGTCTATTTTTTGTGGTACATGATAGTTCTTAATTCCAGCCATGGAGAGTAAGGTAGGGTAGAGATCCTCTATGATGATAGGTGCATGAGAGCGAGTATTTGGTTTTACAATATTATTCCATTTTACAATAAAGGGAACTCTTATACCTCCTTCATACAGAGAACCTTTACCACTCTTGAGTGGTGCATTCTGCGTGTAAAGTTCTCCATCCCGCCAATAGGATGATGAGGCGAGTCCTCCATTATCGCTCATAAAGATGATGATAGTCTCTCGCTTAAGTCCTGCCTTTGCGACCCAATCCATGAGATCTCCCAAACTTTTATCCATTCCTGCAATCAATGAAGCGTAAGCAGCTTCCTTTTCCGAAAGACCACGTGCACGATACGTAGGGTAAAAACGCATATCTCGATCGATTGGTACGTGCACAGCGTAATGAGACATATAGAGATAGAAAGGTTGGTCGTATTTTTTAGCCTTCTCTAATGATGCTATTGCCTCTTGTGTAAGGGCTTCTGTGGCAAAGATACCAGTACCCCAATAACGTTCCAAGCCTGGGATAGCGAATGGAGATGTGGGTTTGCCATCTTTTGTAAAACCGTAGTTACGTTCGCTTAAATAGGTAGCTAATCCACCAGCTGCCGTACCTGTAATGTTCACGTCAAAGCCAAAATGGCACGGATTCTCACCCGGAGTGTCAATAGCTCCCCAGTGAGCTTTTCCGCAATGTATGGTGTGATAGCCTGCATTTTTTAGGAGTTGTACAAAGGATATTGCTTTTGTAGTATGTGCTACATTACCGCTTTGCGCAATACCATTATAATTCCAATCAGGTAATGTTACGCCATCTCGTTTCCCATCCGTCATCTTATCGCGATGTAAAGTCCAATTTGTTACCCGATGGCGAGCCATATTCATACCTGTCATCAGACTACATCTGGAGGGCGAACTGATAGGAGTTGCATAAGCATCTGTGAACATCATCCCCTCGGAAGCAAGTCTTTCCATGTTAGGTGTATCGTATTTCCGATTATTGGCAGTAATCGAATCGGCAAAGGGAAGGGATGTGTCTTGCCATCCCATGTCGTCTACCATGAACAGGATGATATTGGGTTGTGTATTTACTTGTTGTGCTTTGGCTGGGAGGGACACGCCAAGAACAGCTATTGATGTTGTAATCAATAGGGTCGAAGAGTGCTTTGAATTATATAAGGTATAGTTATTCATTGTTGTATCAATCATTGATAGGGGTTTTTAGATAGAGTACAAAGTTAAAAAGAAAGTTGCTAATCACCACATAAATATGATGAAGTTCTTAACCCAAGTTTAACACCCACTTTCGCCTAATTGTTACTGTCACCGTACTTTTCTCGTTTTTCTTATGGGCTCTGTGTCCTACAAATTTTATTCTTTTTGAATGGTGAGTGTTTTAAGTTCAACTTATCGTATATCTGTTTTGCTTGCTTCGAAGGACTACTACATTGGCGCATCTCGATGGTTTCACCTAATGGATTCTTCCCTTTTGTGGTGACGAGCTTTTGGGTACTCATACGTCGTACTATCTCGGTCCAGTAACAGGATTCTCCTTCTCGTTTTAATTGACAACGGATAGTGTTTACCACCCAGTAGGCTAATAAACCGAAGAAGAGGTGTGCGTCGCTTCGCTCATCTTTCTGATGATAGATAGGACGGAGGTTGAGTTCATTCTTTAGTTGTCTGTTCGTACATTCTATCTCACGAATGAGATTGTAGTATTCCCATGTCACACGCTCAGAAAGTGTCCTGACATTGCTGCGGAGGAAATAGACTCCGTGACCAGATTCCATTGCCGAGAGGTCTTTTATCTCCCAGTCTACACGCAGCATCTCCTTGAGTTTCTTCTCATTTTTTATGTAGCTTATCTGGTAGAATTTCGCTATAGAAGGGTACTTCTGTATGGCACGTCCTGTACGTTCAACAACCTTTTCATAGGTCTTTGTTCCACCTTTCTTGGAGATTCCATCGTTTATCCTCTGCAGTTCCATCTCAAAACGCTCTTTCCAAACCCTGTTCATGGACGACTCTGTCATAGCTTTCGAAGGAGATGTTATTTCGAGATAATAATCCTTATCATCCTCTGTCTTAACCTCTTTCAGCGTTATCTTTTGCCGACGGGCATCCATTACCGTAACGCTCTTATTATCATCACTGAGCGTATAGTCCTTCATTTGCGTACGGGATACGCAGAGATAATTGTAACCCTTTTTCTTTATTAACTCCAAGTTCTCTTCCGTGGCAACACCTGGATCCATGATAACGAGCGTATCCTTGGTTCGTGATGGATTCCTCTTTGCCAGTGTATCAATCATATTGGGTAGAGACTTGGGATCTGCTGTATTACCCTCTAAGATAGAAGAATAACGTATAAAACCTTCTTTATTGATACATAATGCAAGTACAAGTAGCTTACAGTCAGAGCGTTTTTCTTTTGAACGACCGAACTTGGCTTTATCGCTATTACGCTTACTACCCTCGAAATAGAAGTTGGTTAAGTCGAAGAGCATCAACTTGTTGTCTATATTAAAGAGATCGTCAGTAACGCTGCACAAATGACGCTCTAACTGTTCCTTTAGTTCATATAATTTGTCAGTGATTTTATACAGAGAATTGATTCCTGGTGTCCAGCTAAGAGCTCCACTATAAAGTTCAGCAGCAGCCGAGTTATCGCGCAAATAATAATAAGATGAACGTTCAGAAACTGCATATACCTTGCGAACAATCAATGCTGACAAAGCCGTGTGTATCGCATTTTCCGTCCACCCGTTTTTGCGCAGAAAACCCTCTAATTGCAGCTTGTCTATTGTCTGCTTGCAGAGCCACTCTGCACCAACATTCCTTGCGTCAGTATAGTTTGCCGTCTCAAGGTCAATATAGTTCTCATATTTTCTCAGCGACTTCTGCTCTTCCTTATTAAACCGATCGATTCCACCTTCTTTCTCCATACGGCTCCACCATTCGTCAGCCTTTGCCTGTTCAATAGGAGTAAGTCCCTCAAGGCGTTCTTTGAAAAGCGAGGGTGTACTTCTATTTTTGAAGCGTTCGGTAAGAGCGTATGCAATTTTTCGGACCTGTACAGCAGTAAGTGAAGGTTCGAACCCGATATTCAACAGAATTAGCGAATGTACATGACCCTGCACGTCACGATATGACTCCTTGATGCGATAATAAGGAGCCATGTCGCCTGTGGCAGGGTTGAATCGTGTCTGTACATTTGCGTGCAT

Protein sequences of DBSCAN-SWA_2

>NZ_CP054011|514250:572912|564858_565731_-|WP_172891353.1|transposase|DBSCAN-SWA
MDHAQDWLLFEDNIGENLSIDETCLSSGEVYTFLTNKAGKGRKGTLIAVVKGTKAEDVIQVLKKINLSKRKTVKEITLDLSSSMMRIARAVFPKALITNDRFHVQKLFYDALDDMRIAYRWMARDKENEEIKEAKSKGKEYIPFRYSNGDTRKQLLARAKFILTKHKSKWTETQKDRAQIIFEHYPTLKKAYDLAMKLTDIYNIKSIKDAARLKLAKWFNEVEELGVDNFYTVIDTFENHYQTILNFFVNRATNANAESFNAKVKAFRAQFRGVTDIPFFLYYCCPVKIK
>NZ_CP054011|514250:572912|569331_570894_-|WP_004361077.1|DBSCAN-SWA
MIDTTMNNYTLYNSKHSSTLLITTSIAVLGVSLPAKAQQVNTQPNIILFMVDDMGWQDTSLPFADSITANNRKYDTPNMERLASEGMMFTDAYATPISSPSRCSLMTGMNMARHRVTNWTLHRDKMTDGKRDGVTLPDWNYNGIAQSGNVAHTTKAISFVQLLKNAGYHTIHCGKAHWGAIDTPGENPCHFGFDVNITGTAAGGLATYLSERNYGFTKDGKPTSPFAIPGLERYWGTGIFATEALTQEAIASLEKAKKYDQPFYLYMSHYAVHVPIDRDMRFYPTYRARGLSEKEAAYASLIAGMDKSLGDLMDWVAKAGLKRETIIIFMSDNGGLASSSYWRDGELYTQNAPLKSGKGSLYEGGIRVPFIVKWNNIVKPNTRSHAPIIIEDLYPTLLSMAGIKNYHVPQKIDGQDITPILRGKQQGDKKRQLIWNYPNIWDGEGLGISLNCAIREGQWKLIYSYLTGQKELYDLSNDLSEKNDLASSHPQLVARLYRHLTSKLHKMNAQKPIVEGEKRK
>NZ_CP054011|514250:572912|534931_535687_-|WP_004360923.1|DBSCAN-SWA
MNIFITGGTSGIGLALARFYAAKGHRVGVCGRNTARIDRSDEVNKLLLAYQLDVCDKDALTVAVEVFCADKGLDMMIVAAGYYRNGVTEEVDFEQTSQMLKVNIAGALNAMEVAREAMNASGGHLVVIASVAGLLHYPCASVYAKCKRALIQIADAYRRSFADYQITVTTLVPGYIDTPRLREIYRNNLSKCPFCMPLNRAVETMTKAIAQRKEQVVFPPKMRLSIAFLSLLPTCLLSAFMHRKTLWSIPK
>NZ_CP054011|514250:572912|571031_572912_-|WP_172891355.1|transposase|DBSCAN-SWA
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKNRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRKVYAVSERSSYYYLRDNSAAAELYSGALSWTPGINSLYKITDKLYELKEQLERHLCSVTDDLFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINKEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVIMDPGVATEENLELIKKKGYNYLCVSRTQMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDKDYYLEITSPSKAMTESSMNRVWKERFEMELQRINDGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKKLKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNELNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGETIEMRQCSSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054011|514250:572912|546767_548456_+|WP_004360944.1|DBSCAN-SWA
MKEIMNMKLKTLILTIALILGASTNIFAQPGAVKKAADAAFTLTTFKADGSILATSNGVCISTDGDGVAVSPWKPFIGADKAVIVDAKGQKHEVECLLGANEIYDIVKFQVSGKTIAAPLATTVSVGDEAWITPMPKSGNAEKADVSSVEKFMDKYNYTILKSSATDKLNGAPVFNVKGQVIGLFNSAGESQSSTDVNYAKDFVVKGLSQNDITLRQSNIRIGLPNTVEEAVVALMLSSEKPTNIHEAIVNEFITKFPQANDGYYALANIQVAKGDFANADKTMQTAISKVTAKDEAHYNFARLIYRNALIPEFAEKTKSVGWTLDKALDEIKKAETTKANDAYRHLQAQIIYAKGDYAKAYTEFEALTKTKFNNPELYLEMAQSRQHLGANDQEILDLLNKSIELCDTPYVSTSAPYFYTRGQQLEKMGEYRKAVQDYYTYEYFNQGRLGAAFYYMREQCEVKGRMWQQALQDILIASQLDPKEALYPTEAGSLLLRLNKVDAAISAAQQAIQLDGSQPDAHLILGIAQCESKQKEEGLKNIQKAKELGNTQADTFLQKYK
>NZ_CP054011|514250:572912|515284_517648_-|WP_036886647.1|DBSCAN-SWA
MRKKLFFITILLFILTLPANAVLQEDSLKNSLQVLRHELIAQHLEQTKQLNNSRFITEQVTNQLKEIGDKSAQVSLMLYSQKTDNIFDLTYACQQATELWKDFQTKTRPFHDLITESNEEIARYDSLVNVLSTMYTFGLTQKMKTDRNVCLTLAVSIRRMLKERNDSYQEYIQYYNYSQHQLQALDAYAQKRYAEIQSGIFTNTGDSYFKVLKSVRFRLSQMNTTLSEKYTPNTVVVSQWDVKWIITLFSMILIYGLIAIIINYLSIRFLVTRVMKTNRFEQKSQSFLAKRTCIIMLASVITFSIVLIIIRLFSPSNFVHMACSLLLEYTWMLSVIFASLLLRVEGSQTHNAYRIYYPLIMIGFFVIAFRIVMLPSSVVTLLFTPLLFIDTLWQARMIHKYHKLVPHYDLNFAYISQFVFIFSLISASIGYTMFAVQVIIWWSMQLACILTIAFFKDYLNQYREKHPIKKLSPAKVWLLRFVDIVLIPTALVISFILAIYWATDVFNLSGLTWNLFRANFIDSDKIQISVYSIAVVTILWFIFNYLNLTIRDAIKLYLKRNDPSTAEARATMYINVLQVIVWGAWLLITLGFFKVSSTWLVVVTGGLSTGIGFAMKDILENIYYGISLMAGRIKIGDYIICDGIRGKVSSINYTSTVIDALDGSTIAFQNSQLFTKNYKNMTKNDGYEVGTIQVGVAYGTNVKEVRELLKDAIAKLGITNEKKDIIVRLQSFDDSCITLKILVWLNVLTQGNDIAVIMECIYDTLNNNGIEIPFPQREITIKHQQEI
>NZ_CP054011|514250:572912|520290_521865_+|WP_004360904.1|DBSCAN-SWA
MKLENKEFGFDSFASEMAKLKNEKHFDYLVTVVGEDFGAEEGLGCIYILENTNTHERCSVKQLAKKVGEEHVIPSVYNIWADADLLEREVYDFYGVKFLGHPDMRRLYLRNDFKGYPLRKDYNMDPAKNMYTTEDDVELDTTTEWNLNNNGELVGTQRPLFTDDNFVVNIGPQHPSTHGVLRLQTVLDGETVTKIYPHLGYIHRGIEKLCEQFTYPQTLALTDRMNYLSAMMHRHALVGVIEEGMGIELSERILYIRTIMDELQRIDNHLLYTSCCAQDLGALTAFLYGMRDREHVLNVMEETTGGRLIQNYYRIGGLQADIDPDFVSNVKELCKYLRPMVQEYLDVFGDNVITHERFRNVGVMDEQDCISYGVTGPAGRASGWKNDVRKNHPYAMYDKVNFEQITLTHGDSMDRYYCHIQEIYQSLNIIEQLIDNIPEGEFYIKQKPIIKVPEGQWYFAVEGASGEFGAYLDSRGDKTAYRLKFRPMGLTLVGAMDKMLRGQKIADLVTTGAALDFVIPDIDR
>NZ_CP054011|514250:572912|567479_568775_+|WP_004361076.1|DBSCAN-SWA
MYALLGVGIFYTVYLGFPQIRHLNLAFKYAFGPIFKKRKPGETKVNSFQALATAVAAQVGTGNIGGVATAIASGGMGAIFWMWVSALLGMSTIFSEAVLAQKYKKEYHGETVGGSAYYLYYGLGSKWLAVCFSVAIVLALGFVGNMVQANSISIALNNAFHIPSYIIGVVLAAVVGVVIIGGQRRITAIAELLVPFMAIVYILGSLVIIYMFADQLPHVIRTIFQDAFSMKSAAGGAAGTVMKYAIRYGVARGLFSNEAGMGSTPHAHALADVKDPSEQGFIAMAGVFVDTVLICTSTAFVIMLTGSFQNLSLKSVAITQESFEIAFGNGGIIFLAISLIFFAFTTIIGWYMFAEMNIKFMFGKKGILSYRALVVLFVFLGCLFAADMVWELADTFNGLMVIPNLIGIIFLAPQVKKIYKNFLANRKENNS
>NZ_CP054011|514250:572912|524098_524407_+|WP_004360908.1|DBSCAN-SWA
MIPVGYFFVLSGLLFFIGVFGFVTRRNLVAMLISVELVLNSVDINFAAFNRLLFPDGYEGMFFTLFSIGVSAAESAVALAIIINVYRHFHSDQVNSIENMKL
>NZ_CP054011|514250:572912|538532_539765_-|WP_172891309.1|transposase|DBSCAN-SWA
MNKSTHFIGQPLYVQLLNYFNRDKILSLSQAQGGEHYIKKFDAWHHLVVMLYAVMMRLDSLREIKASLFANVNRFNHLGLKHFPCRSTLSDANKRRDSEIFGSIYMNLYEKYRHELYSDSRNCGQPKWLKNLKIIDSTTISLFSNLVFKGVGRNPKTGKKKGGIKVHTEIFANENVPSDIKFTSAASHDQFALIPERYANEELIAFDRAYINYEKFSELTQRGVIYVTKMKNNLSFERIADTDYQMTTDYGVVRVETILFHKHTKEKDIYHKARKITYQDKTKKGKIRFISLLTNDFQMSAEDIIAIYKRRWQIETLFKQIKQNFPLRYFYGESANAIKIQIWITLIANLLITLVKNKIKRPWSFSGLATMIRILLMSYVAIQSFFEQPHRDWDRLITQVKAPPEELSLF
>NZ_CP054011|514250:572912|535683_536724_-|WP_004360925.1|DBSCAN-SWA
MKKKPYPTVAVFSGGGTRYALYLGMYAAMQHYGVKPDLLIAACGGSIAANIINSFATDEQRKAFIQSEELYRFVQNTRMTRFKMLYKIGVYCQRKVRNTFYAPYIENIFDKFIVDMPTDIRPLLPSLAVRPTLPTIVVGARLLFDRADIGKERNGRKLYRKVLFTDAETARNIDLLAVNCNFKSYEGSAIDSQVELFQDVPLPIATRISVSDMFYVQPVHYKGAYFAGGIIDLMPIELAEQLGETIIFEKKKGFGTIDEALIRAVFGYSGNRRLQEVMTHSVNYWVDTADMNQALSGHYIEKNINLLKLQVELKLPKTYAQFVKDMNFQWQYGYDRVAQHFKNKQV
>NZ_CP054011|514250:572912|526478_527990_+|WP_036886650.1|DBSCAN-SWA
MSWILTVFVIIPVLMLFALWVAKNDNQVRGVMVAGSTALLVGAIWLTVYFVQQRNAGNHDAMLLTNSVMWFKPLNIAFSVGVDGISVVMILLSAIIVFTGTFASWQLEPMKKEYFLWFVLLSSGVFGFFISTDMFTMFMFYEVALIPMYLLIGVWGTGPKEYSAMKLTLMLMGGSALLVLGILGIYYFSGATTMDVMELARMHAMPKNIQNIFFPLVFIGFGVLGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCLRIAMFLMPDALEMWAPVFLVLTTISVVYGALSACVQTDLKYINAYSSVSHCGMVLFALVMTTQTAITGAILQMLSHGLMTALFFACIGMIYHRAGTRDVRYLGGLMKVIPFLAVSYVVAGLANLGLPGFSGFVAEMTIFVGSFENTGTFHRVATIIACTAIVITAVYILRVVGKILFQKIPNKKFYELHDATWDERFAIGCLIFCVAGLGLCPLFFENMIMDAVHPIFDHIFTYIPNLGNL
>NZ_CP054011|514250:572912|528002_529442_+|WP_004360914.1|DBSCAN-SWA
MNYSDFFKMIPEASLIAILIVLFVADFATAKTEERKWFNPLASVLLLLNTFVCLYPMGTQSLFGGMYETTPAVDVMKAILSMGTFIVVVQSRVWAAKSGKEAEFYMLIVSTLLGMFTMMSAGNFLMFFLGLEMASVPLSCTVAFDMYRKNSAEGAAKFILTATFSSGVMLYGISFLYGQFGTLYFDDIATKMQATPLVIMGLVFFFSGLGFKISLVPFHFWTADTYQGAPTTVTGYLSVISKGAAAFTLLSILFHVFDGMMEYWHVLLMIVVVLSITIANLFAVRQNELKRFMAFSSISQAGYIMLAAIGNNWANSVAALSYYVLIYVVANMAVFTIISVVEQNNGGKTNIDDYNGFYQTNPRLSFLMTLAMFSLGGIPPFAGMFSKFFIFMSGVNGADINTTMGAWAYGVVFIALLNTVISLYYYLKIVKAMYIVRTDNPLPTFKSDCNTKFALAICMAGILLFGVCSFVYEWIAAAV
>NZ_CP054011|514250:572912|540243_540645_-|WP_004360933.1|DBSCAN-SWA
MDLQGKVIAVLPAREGTSARGPWKSQEYVIETHDQYPKKMVFNVFGADRIEQFAIKAGDELNVSFDIDAHEYNGRWFNNIRAWNVQRVDATAAMAGTPVAAAPVTPQPAPAAPQATPFPPAQPEENSTDDLPF
>NZ_CP054011|514250:572912|523562_524102_+|WP_036886648.1|DBSCAN-SWA
MARLIMFAVLAVIILASAVFCVSTKRIMRAATALLFVLFGVAGLYFLLDYTFLGAAQISIYAGGITMMYIFAIQLVSKRTLQGLSERWLGKRTFLAAFIALVGFGTVILVLLKNQVLRHTVVNGDSLSNEVTMETIGRNLMTANKYGYVLPFEFISVFLLACIIGGLVILNNKKKEESK
>NZ_CP054011|514250:572912|519345_520272_+|WP_004360903.1|DBSCAN-SWA
MEIRKPKIKSLPYDEWKDNDTLSKMASELNDGGTNLVLGNLDQLINWGRSNSLWSLTFATSCCGIEFMSVGCARYDFSRFGFEVTRNSPRQADLIMCAGTITNKMAPALKRLYDQMAEPKYVIAVGGCAISGGPFKDSYHVMRGIDEIIPVDVYIPGCPPRPEAIIYGMMQLQRKVKVEKFFGGVNHKQSTEERELGKSNAELIFSEKLGINPEEIKEKREAAWNEAKNPAPKPARPVVKPTAAAVKPADVSAKPAEAATTSSEPVAPKKDTIVVNQPVTQEDVEKLGKEIDQIDATSKAADETATNN
>NZ_CP054011|514250:572912|545073_546744_+|WP_004360943.1|DBSCAN-SWA
MLKHLYIKNYTLIDQLDIAFHSGFSVITGETGAGKSIILGAIGLLLGNRADSKQIKQGEKKCTIEAHFDLSNYGFESFFEEQDVDFEPEDTIVRRELTATGKSRAFINDTPVSLQMMRVLGEQLIDIHSQHQNLLLQKDDFQLNVVDIIAQDTKELAAYRSAYQDYKETERRLSDMREQISKAQENEEFMRFQFNELDNANLIEGRQEELEQESETLSHSEDIKTAFYEADNLLSDDDNGVLRKLGQSLDSLGNIEKVYPKAQELIQRLSSVHIELKDIAGEIGSEVENIDFDPSRLDSINQQLDLLNTLEQKYHVSTEKELIEIRDNIANQLKNIDNSDEEQEILEQEVKTKLSTCEKQAEKLTTLRRKAAKIVEEQMSSRLIPLGIPNVRFKVDLSPKPLTMDGADKIQFLFSANTSTAMEPVAQVASGGEIARVMLSLKAMVSGAVKLPTIIFDEIDTGVSGKIAQKMALIMQEMGNNNRQVISITHLPQIAALGTSHYKVEKEETAEGTRSHMRELTQEQRVNEIAQMLSGADVSDAALQNARELLDLSKKK
>NZ_CP054011|514250:572912|551892_553197_+|WP_172891351.1|DBSCAN-SWA
MNPVRLELLKIDRQWYEQVKAHTDKPLFVCLGEKHTLNMFDVYFKSHGADEVESDDVFLVNYKPFEDAQRYGAELLEELHLVYNLWREHNLISVPCKEWNTDIVVPNDKVKTDAGNTAKALIGLYESFPPLRGHKIFILLSPQQISSIPLYEQWLFDWCANMNSSDVKIVVLEKHEGRLLKNLPENRHEFVLTGTDIASLMNNVAAQTAADPNDEENVLQQQMLLANVHFSRHEFDNAHVALAKAIGIASRHNLKDVLCTAHLLDAYVWLTQNEQEKAHDTFRTLLSLTGEGTLLSAQMHVNYGGFLLAIRRKEDAIDAFEKSAEIAKNIKNPLLEMECYRIMGQIQDGTFTDSQTIAYYEKCIEIGMTMNNEERQQSSLAYIATLLLKKYGNSKKTEELCKQMEQYLGADWQTNIQVPNMDDLYHSPLTSVSS
>NZ_CP054011|514250:572912|536751_537378_-|WP_004360929.1|DBSCAN-SWA
MISVYSIKPQFQRVLTPILELLHRAKVTANQITLWACVLSLVIGILFWFAGDVGTWLYLCLPVGLLIRMALNALDGMMARRYNQITRKGELLNEVGDVVSDTIIYFPLLKYHPESLYFIVAFIALSIINEYAGVMGKVLSAERRYDGPMGKSDRAFVLGLYGVVCLFGINLSGYSVYIFGVIDLLLVLSTWIRIKKTLKVTRNSQTPE
>NZ_CP054011|514250:572912|542077_542932_+|WP_004360937.1|DBSCAN-SWA
MKLNLTKPLIVFDLETTGLDLVNDRIIQISFIKVHPDGKEERENIFINPEKPIPAEVTLLTGISDADVADAPTFKQKAKDLSDKFAGCDFAGYNSNRFDVPMLAEEFLRAGVDFDFSKCRLIDAQNIYHKMERRNLAAAYKFYCGRKMEDDFEAHKADQDTEATWRVLQGELDMYAPGNQEEEDRVLNNDMDELAEFSRMNDFVDFAGRIVWRDMTDKDGNQLLDATGKPRRHEVFNFGKYKGWDVAEVLRKDPGYYSWMLASDFTYNTKQVLTRIRLREFNNK
>NZ_CP054011|514250:572912|549499_549898_+|WP_004383461.1|DBSCAN-SWA
MSSFRATLELGGKEYDVLYSNYEFSRTTDKKGQPASSISGGRISVTIESTDDTSTIEAMLNSQFKPVEGKIVYKKSEEDAKMKEISFKNAYIVHYKETLDVNNEAPMTIAMTFSAENITVGNAELDNRWPRT
>NZ_CP054011|514250:572912|550073_551885_+|WP_172891350.1|DBSCAN-SWA
MSIPFNPITISVGKKSLSSFISLQIEQNIGKHHRFQMSVELETGSNRYVHNINSSKEWLGESIVVKAANTPIFVGVVTNVQLHREGSDFGCIIVSGYSATYRLETAHSCFSWNDRTIGDVVKKLCEQAKVQLELNPAFKETKDFICQYEESDFDFIRRLAHQYQEWMYFDGTKLIFGKPRKLADPIRLEYGTTLSSLDIGLQTLARSEEVFSYHSGADHEMQRMTPDLAYGHDKLAGDAFRASLGMFSKPARQHALPRISDESELINYMGRKQAAETAETHYITAESQVPTLRVGSVVSLYSSFLERVGNISKESLGNFIIIEITHEVSQGSYYKNRFKAIPATIKALPSPKVRMPLAETQMATVLSNADPQGKGRVRVRMNWQTDGMQTGWVRVMTPDGGSSKDVKSNRGFVFIPEVGDQVLLGFRHGDPARPYVMGSLFNGTTGGGGGQGNNCKSLTTRSGSSLKLDDSKGSVTLADPGKTSIHMDGAGNATFDSSDKIIISCGSASIELHNDGTIKINGKEISVGGTDVSIAGTSSIVAGVGEGETPSTGIGMSTTELNISSSKTYIDGSSETSVSSSGGTTSVTASSEVIVGGSKVKLN
>NZ_CP054011|514250:572912|562550_564431_+|WP_172891352.1|transposase|DBSCAN-SWA
MHANVQTRFNPATGDMAPYYRIKESYRDVQGHVHSLILLNIGFEPSLTAVQVRKIAYALTERFKTRSTPSLFKERLEGLTPIEQAKADEWWSRMEKEGGIDRFNKEEQKSLRKYENYIDLETANYTDARNVGAEWLCKQTIDKLQLEGFLRKNGWTENAIHTALSALIVRTVYAVSERSSYYYLRDNSAAGELYSGVPGWTPGINSLYKITDKLYELKEQLERHLCSVTDDLFNIDNKLMLFDLTNFYFEGSKRNSDKAKFGRSKEKRSDCKLLVLALCINKEGFIRYSSILEGNTADPKSLPNMIDTLAKRNPSRTKDTLVIMDAGVATEENLELIKKKGYNYLCVSRTKMKDYTLSDDNKSVTVMDARRQKITLKEVKTEDDEDYYLEITSPSKAMTESSMNRVWRERFKMDLQRINEGISKKGGTKTYEKVVERTGRAIQKYPSIAKFYQISYIKNEKKPKEMLRVDWEIKDLSAMESGHGVYFLRSNVRTLSERVTWEYYNLIREIECTNRQLKNDLNLRPIYHQKDERSDAHLFFGLLAYWVVNTIRCQLKREGESCYWTEIVRRMSTQKLVTTKGKNPLGENTEMRQCSSPSKQAKQIYDKLNLKHSPFKKNKICRTQSP
>NZ_CP054011|514250:572912|540857_541982_+|WP_004360935.1|DBSCAN-SWA
MRFNLSSTALSSRLLTLSRVINSKNSLPILDCFLFEVHDGQLTITASDSENVMRGTLNLESCEGEGNFAVNNHTILDAVKELPEQPLTLDVNLDEMKIYVTYQNGSYNFPILGADEYPKAQSVSDNATTITLQAEKLSDSLTRSLFATAQDELRPVMNGVYFDLKEDGLAIVASDGHKLVRNKIFSIKSDSPASFVLPKKPASLLKNVLSKDGGDVIIRFDERSAEISFAEGNLACRLIEGKYPNYNSVIPQDNPNQVTIDRKSLIGALRRVLPFASDSSQLIRFHVSAGLLELNAEDIDFATSAKESVTCEYGGNPMSIGFKGSSMLDILNNLESDDVVIQLADPSRAGVIVPGTQPENEDILMLIMPMLLND
>NZ_CP054011|514250:572912|514250_515168_+|WP_172891349.1|transposase|DBSCAN-SWA
MITKDKITEIFCIADDFCKEFELETDKIGLSEKNKGCHRHRRWRMSKSEIITILICFHFNSYRNFRHYYTFFVKEHLADLFPNQLSYNRFLELEARVSVEMMMFLQICCFGRCTGISFIDSTCIPVCHNKRICRNKVFRNYATRGKSTMGWYFGFKLHLICNERGEILNFMLTKANVDDRDENVFNRLTDNVFGKLFADKGYISQGLFERLFNDGINLVTGIRSNMKNKLMPLYDRLLLRKRSVIETINDELKNVAQLVHSRHRSIFNFAMNVLSAIAAYSFFEKKPAVNIDFAIEQHSGQLTLF
>NZ_CP054011|514250:572912|544113_545010_+|WP_036886658.1|DBSCAN-SWA
MILLTSLFLFSNGELSAQELNAKVTVNHNQIQGTDASVFENLQQTLEQFINTRQWTHYQFQRNERINCNFNITVSKYDPGSNLFTCSALIQANRPVYNAAYSSTLYNNQDGDFNFTFAQFDQIEFNEENIDNQLTALIAYYAYLIIGLDLDSFSPMGGEDILQRCMVLTNNAQNLNFTGWKAFDNSRNRFAIINDYLDGAMKPFRQLQYDYYRTGLDEMANNVERGRTNITSALENGLKKAHENRPISMLPQIWTDYKKDELANIYKGKGTQKEKELVYDILFSINASQNITWDKIKQ
>NZ_CP054011|514250:572912|531979_533677_-|WP_004360920.1|DBSCAN-SWA
METGTFKSFDNADIFYRVWNYNPSQKTIVILHRGHEHSGRLQAFAENEQFVHFNIFGFDMRGLGHTSQSVSPHFMDYVRDLDAFVKYLYEQYGIVERDIFVVANSIAGVIVSAWCHDFAPRIAGMALLAPAFTIKLYVPFAKTGIALAARLFKHLTVPSYVKSKVLTHDVEQQKAYDTDPLITREIDAHYLLDLLKAGKRIVEDAAAITIPTLLLSAGKDYVVKDDMQKRFFVDISSTQKRFVKLKGFYHGLLFETQREQVYNPIAEFINRCFSLEQPPATCMPDKFTVDEYNKMTLNMLPRIERWGFRMQKWMLHHLGFLSKGMRVGLKYGFDSGMSLDYVYRNQAQGCGPIGRWIDKGYLNAIGWRGVRIRREHLIAAVEERIETFKQRNEPVKILDIAGGTGNYLFDIKRKFPEIEVVINDFSEANIAFGEAQIQQQGLQNIRFTRLDCFNKDSYRQLNFEPNIVIISGIFELFGDNELVCKAISGALSALQPGGFLVYTGQPWHPQLKMIAFVLNNHQERDWIMRRRSQRELDSLFAFYGLTKYGMKLDNFGIFTVSYGTK
>NZ_CP054011|514250:572912|517832_518723_+|WP_004360901.1|DBSCAN-SWA
MILIADSGGSKTDWALISLPTDTSKYVLKVRTQGVNPFHQSKEVILKILEQELKPVLYKAAEQNDSFLPKKDIAEYVSQIAFYGAGCTKNLSSVVSEALTVSFPSALIKVESDLLGAAHAVCGYDAGIACILGTGANSCQYDGENIVANVPPLGYILGDEGSGAVLGKLLLNGIFKGDLSTEIRDLYLEWSGLTYPEIIDKVYRQPLANRYLGGISKFIKENLQYAELESLVRFNFDNFFKKNILKYTTTSVRKISAVGGIAAAFEEQLRMSASTFNFKVGKVIASPIDGLIEYYS
>NZ_CP054011|514250:572912|523013_523550_+|WP_004360906.1|DBSCAN-SWA
MEDKKQSYFGEVGSALKTLATGMKVTMKEYFTPKSTEQYPENRKTTLHVAKRHRGRLVFKRDEEKNHKCTACTMCEKACPNGTIKILSEMVTNEETGKKKKQLVDYEYDLGDCMFCELCVNACNFDAIEFTNDFENAVFDRSKLILHLDKEVYEGGSLPGLIDGGADWKVGTFNTKKK
>NZ_CP054011|514250:572912|557485_557950_+|WP_004360949.1|DBSCAN-SWA
MNKLNEFINGEKYEFLLRNIQKKSNIEIDSTIPFVLLDYDKEMLIAARIEIEDLESLLNSYMTEIVSFVERKMKYDFEDEDEYPEGEELSDDEKPKTIIELPYYKNFLIAYLIEYYLLKKQPAELGKYLKRIHISHATKYERDLKDIWRETLES
>NZ_CP054011|514250:572912|519004_519355_+|WP_004360902.1|DBSCAN-SWA
MYFTLFVTVLITAAFLVVAAYAIAKWIGPRSYNPAKGEPYECGIPTYGTSWLPVHIGYYFFAILFLMFDVETVFLYPWAVVVKTFGPLALATIGFFMLVLVFGLAYAWRKGALEWK
>NZ_CP054011|514250:572912|542936_544148_+|WP_004360939.1|DBSCAN-SWA
MLKGKKIVLGITGSIAAYKSCLIIRELIKSGAEVQVVITPAGKEFITPITLSALTHKPVVSEFFSQKDGMWNSHVDLGLWADAMVIAPCTAATLGKMANGVADNMLITTYLSMKAPVFIAPAMDLDMYKHPSTQKNIETLRSFGNHIIEPGSGFLASGLEGKGRMEEPENIVKALADFFSTSSESPSYTEDLKDKKILITAGPTYEKIDPVRFIGNYSSGKMGFALAEECSRRGAKVVLVAGPVSLTCSDCIQRVDVESCREMYEAAVGEFPNCDAVILCAAVADFRPETIAEQKIKRVGDELLLKLKPTQDIAATIGSMKGEGQRIVAFALETNEEESNAQRKLEKKNADFIVLNSTRIPGTTFQADDNQITIINKEGKKSYAKKPKTEVARDIIDELVSIL
>NZ_CP054011|514250:572912|559840_560398_+|WP_004360951.1|DBSCAN-SWA
MNKVAKISLDSSSTEIGRIGGNIPTCFLEKKENIEGFKFYMTIQNPDNSDEYISIFVPDSYDTMVDENIYPNCSIKVFTHSFSVESSNNFYTLKELHKSSLMGYKEVENEEFDFVTKTQHPQLIQYEDYYLKKLDEDGFTFYLQIDEDYYPENLLSGNYILGYGALYLYKHKITGNIIVGFWQYS
>NZ_CP054011|514250:572912|524419_526474_+|WP_036886649.1|DBSCAN-SWA
MFDYAFLILLLPFLSAVVLGLFGMKMPRKVAGIIGTCMLGTLFVLSLYTAYHYFFYTGEYTAMGETFNVTDGRLANGTYPTVTVFNITWLKFTELLTFNIGFRLSPISVMMLIVITTVSLMVHIYSFGYMAERDENYKFEEYEHGFQRFYAYLSLFTMSMLGLVVATNIFQMYLFWELVGVCSYLLIGFYYPKHTAVHASKKAFIVTRFADLFFLIGILFFSFYVGTFNYDLNVNPGLAETLNGLAKNPHLTWVLPTALFLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVFQVASLLPIYVQFGAQEQLHWIAWIAAFTAFYAAAVACAQRDIKRGLAFSTISQIAYMLVALGVCFYEKEHGSFYSAEYLHHGGLGYMAAMFHLFTHAMFKALLFLCSGAIIVIIGSNFKEYMGGLHKYMPITNICFLIGCLAIAGIPPFAGFFSKDEIISACNALPGVEGQALKWIMTLVAGMTAFYMFRLYYVIFWGESYYEQDPENRRRPQEVPFVMWGPLVFLAIISITAGWIPFGHFVSANGLNYDIHLDWSIATTSIIAAVIGIALATWMYMGKKQPVADALQRTFPRLHKAALNRFYIDNAWQFFTHKIVFRCFSIPIAWFDRHVIDGTFNFMAWGTQEAGESIRSWQSGDVRQYAVWFITGTVALTLVLLCLI
>NZ_CP054011|514250:572912|533657_534950_-|WP_036886654.1|DBSCAN-SWA
MEHSQINNKTVWTCKRPLPNGLMQRCGIDNKCLQVSKYIALVICWGVFYAVYTFAASYAASLKEVSSLCFSFEKAIPFVPFAIYFYSSSVVFFIWVFFLCNTFRQLSTLSKRIVFITVLSGICFIIFPLKQSFVRPETAHILFSFINTYDTPFNQVPSLHIGYACIFWSGVRNSRFRNLLRMWLVLLMLSTLLVYQHHFIDITTGLMAGFLTLWMFPYRKKRNQQIATVYFFVAAVGLTALLFAIEHSVLGSIFLLWGILVLLLLGRAYYRSNRHFLKDDHGCIGFLRYIFYFPYIAVYRILWVFSRQAPVEIAPNIFVGGLLSCRSARKFAMLGEVSVFDLSAELPENAYFRTSADYHCFPLLDIATIPKACEERIVNTVLEKMKAEDVPRKLYIHCAMGRFRSRRIGETVQLMISKNLTKDKNGNRNI
>NZ_CP054011|514250:572912|521909_523001_+|WP_004360905.1|DBSCAN-SWA
MFDFRIVTTWFDELLRVTCGLSNFWTVLIECVAVGLAILLAYALLAIVLIFMERKVCAYFQCRIGPVRVGWWGTLQVFADVLKMLIKEIFAVDKADKLLYYLAPFLVIIASVGTFSFLPWNKGAHILDFNVGIFLVTAISSIGVIGVFIAGWGSNNKYSVLSAMRGAVQMISYELSLGICLISAVILTGTMQISGIVEAQTGPLQWLIVQGHVPATLAFLVFCVAGNAEANRGPFDLAEAESELTAGYHTEYSGMGFGFYYLAEYLNLFVVAGIATTVFLGGWAPLNIGLDGFDAIMNYIPGLVWFLGKTFTVVFLLMWIKWTFPRLRIDQILKLEWKYLMPLSLVILVLMTVCVAFGWTIHY
>NZ_CP054011|514250:572912|561404_561824_+|WP_036886665.1|DBSCAN-SWA
MKTELIERINSYLNKYQSFNPQPANDKDIKQAEVMLNVVFDSDYKQFIKTFGGCYVGVDIYGIRSSNDLKEKTVVDLTKLYKEAGWAIADDCYIISFDSSGNPIMMNKSGEVVLFDHDNGDSVILANSFEELIEDNLPD
>NZ_CP054011|514250:572912|565846_566191_-|WP_172891354.1|transposase|DBSCAN-SWA
MKSHQLLRCIFPDVLADYFDVVDIQESACQFDFWLDERNFMEKSDHKLGTVSSYGFTSERVIQDFPLRGKAVYLHVRRRKWRDSSNGEIFTYSYDDLTAEGSKLSPEFVSFLKE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172891349.1|514250_515168_+|transposase	IS982 family transposase	NA	NA	NA	NA
WP_036886647.1|515284_517648_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004360901.1|517832_518723_+	hypothetical protein	NA	NA	NA	NA
WP_004360902.1|519004_519355_+	NADH-quinone oxidoreductase subunit A	NA	NA	NA	NA
WP_004360903.1|519345_520272_+	NADH-quinone oxidoreductase subunit B	NA	NA	NA	NA
WP_004360904.1|520290_521865_+	NADH-quinone oxidoreductase subunit C	NA	NA	NA	NA
WP_004360905.1|521909_523001_+	NADH-quinone oxidoreductase subunit NuoH	NA	NA	NA	NA
WP_004360906.1|523013_523550_+	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_036886648.1|523562_524102_+	NADH-quinone oxidoreductase subunit J	NA	NA	NA	NA
WP_004360908.1|524098_524407_+	NADH-quinone oxidoreductase subunit NuoK	NA	NA	NA	NA
WP_036886649.1|524419_526474_+	NADH-quinone oxidoreductase subunit L	NA	NA	NA	NA
WP_036886650.1|526478_527990_+	NADH-quinone oxidoreductase subunit M	NA	NA	NA	NA
WP_004360914.1|528002_529442_+	NADH-quinone oxidoreductase subunit N	NA	NA	NA	NA
WP_004360920.1|531979_533677_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_036886654.1|533657_534950_-	phosphatase	NA	NA	NA	NA
WP_004360923.1|534931_535687_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004360925.1|535683_536724_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004360929.1|536751_537378_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_172891309.1|538532_539765_-|transposase	IS4 family transposase	NA	NA	NA	NA
WP_004360933.1|540243_540645_-	DUF3127 domain-containing protein	NA	NA	NA	NA
WP_004360935.1|540857_541982_+	DNA polymerase III subunit beta	NA	NA	NA	NA
WP_004360937.1|542077_542932_+	3'-5' exonuclease	A0A1P8VWC8	Flavobacterium_phage	7.5e-39	40.2
WP_004360939.1|542936_544148_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.1e-35	31.9
WP_036886658.1|544113_545010_+	DUF4835 family protein	NA	NA	NA	NA
WP_004360943.1|545073_546744_+	DNA repair protein RecN	NA	NA	NA	NA
WP_004360944.1|546767_548456_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004383461.1|549499_549898_+	hypothetical protein	NA	NA	NA	NA
WP_172891350.1|550073_551885_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_172891351.1|551892_553197_+	hypothetical protein	NA	NA	NA	NA
WP_004360949.1|557485_557950_+	hypothetical protein	NA	NA	NA	NA
WP_004360951.1|559840_560398_+	hypothetical protein	NA	NA	NA	NA
WP_036886665.1|561404_561824_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_172891352.1|562550_564431_+|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_172891353.1|564858_565731_-|transposase	transposase	NA	NA	NA	NA
WP_172891354.1|565846_566191_-|transposase	transposase family protein	NA	NA	NA	NA
WP_004361076.1|567479_568775_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_004361077.1|569331_570894_-	sulfatase	NA	NA	NA	NA
WP_172891355.1|571031_572912_-|transposase	IS1634 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP054011|894240:901584|DBSCAN-SWA
TATGGCAATAGGCAAATGGATTGGTGGCGCATTAGGCTGGATACTTAGCGGAAATATGCTGGGTGGTTTAGTTGGCTATTGTATAGGAACAATGCTTGACGAAGCATTTGCAGGCGATAATAGAGGTGGTGATAGGCAGAACGGATATGGCGAGCAAAGTCATTTTGGAGGCACGCGTCCGTTTGAAGAAGACCGCAACTCCTTTTTGTTCTCTATGCTTGTCCTTTCCTCTTACATTATAAAAGCCGATGGAAAGATAATGCACTCTGAGATGGAATATGTACGCCAATTCCTTCGTCATAACTTCGGCGAGCAGGCTGTAAGCCAAGGAGAATCAATTCTGCTAAAGTTATTTGATTTACAGAAGCAACAAGGCCCTTACCAATTTAAAGAAACAATCCGTAAGAGCTGTGTTGAAATACGTTTTCATACAAGTGTCAGTCAACGACTACAATTACTAAATTACCTTGTCATCATAGCAAAAGCAGATGGCATAGTAAGCCCAGAAGAAGTTGTTGCACTGAAAGAGATTGCCTTATATCTTGGTCTTTCTGCGCAAGACATAGAGTCCATGCTCAACTTAGAAAGTGGAGCAAAAGCAAGTAGTAACATTGAAGATGCCTATAAAGTATTAGGGGTATCTCCATCAGCAACAGACGATGAGGTCAAGGCTGCTTACCGCAAGATGGCACTTAAACATCATCCAGACCGTGTTTCTACACTTGGAGACGATATCCGAAAGGCTGCTGAAAAGAAGTTCCAGGAGATTAATGACGCCAAAGAAAGAATCTATAAGGCAAGAGGACTGTGAGGAAAGTGGACAGGTTTATAATTGACAAGTAAATGCTAATCAATTCACAACAAACATCTTCATTAAGAAACAATCATAAATTGCACTATGGCAACAAGACTTAAAATAAAAACAACAGAAGGCGATATCATTATTCGCCTTTATGACGAGACTCCAAAACATCGTGATAACTTTTTAAAGCTTGCAAAGGAAGGGTATTTCAATGGTACGCTCTTCCACCGAGTAATAAAGGACTTTATGATACAAGGTGGTGATCCAGATAGTAAGAATGCTCCAAAGGGTAAGATGTTAGGTACAGGTGGACCAGACTATACCATTCCTGCTGAATTTGTGTATCCACAATACTTTCACAAACGTGGTGCCTTGAGTGCAGCCCGCACAGGTGATGAAGTTAACCTTGAGAAAGAAAGCAGTGGTAGTCAGTTTTACATTGTATGGGGAAAGACCTTTAAGCCTGCAGAACTGAAGCAAATGGAGCATCAGATGGCAATGCAACAAGAGCAGCAGGTATTCAATCAGCTTACAAGAGAACATCACGAGGAGATAATGAATTTAAGACGTAATCGTGACCGTGTAGGACTGCAAGAGCTACAAGACAAACTGATAGAACAAACAAAAACAACTTGTAAGCAACAAGGTAAGCCTTCCTTTACAGAAGAACAAATAGAGGTTTATACTAATGTTGGTGGTACTCCTTTCCTCGATAATCAGTACACCGTCTTCGGTGAGGTGGAGGAAGGTCTTGACATCGTTGAACGTATACAAAACTGCGATACAGACCGCAACGACCGTCCAACAGAAGATGTTAAGATAGAAACTGTAGCCTTATTGTAAGCCTACATAATGAAACATAAAATGACATAATATCCTCGTATAGTTATTCCAGCAAGAAATAACTATACAAGGATATCTTATTTAACCCAGCAGGTTTAATCTTTCTTAGCGAAGATAGTATGACAACTGCTCTAAATTCTTCTGCTTAGTTGCGTCCGTTATCAAAAAGATATCTATAAGCCACCAGATACCACAACCACCAGCTGTCAACAACTTACCAATACCTAAACCAACATCTCCAATATAGAAGCGATCAATACCAAGTGATCCTATAAATATTGACAAAAGAATTGATAGCAAAGGATCTTTCATCTGAGACTGGAGAGCCAATATCTCTGACTCACTAATATCAGTGTTTTCCAATCTTGTACGAACACTCGGAATACTTCCTGCAGGGATTTTTGATGAAAGCATCATCAATATATGATTCACCTTATCTGATTCCATAATGATTACCTTAGGTTTAATAATTTATATAACTTTACATGTTCCCCAAACCTATATCCACTATATCTTTAGGATATTTCTCACAATAAACCAAATGAAAAAGAGAATTATATACAACCATATAAGCCGCTTATCTTCTATTACCTTTGTGAGACTATCCTTAGCCTTCCCTTTTGGAAGTAAGGCGCGTACTCCAAATGATAAGATGTATGGTCCAGAAAATAAAAGAAAATAATTATAGTGGATTGCTTCTGAAAACCGCCCTTGCAATAAAGCATGCAACGCACGTTGAATGCCACAACCAGGACATTGTAACCCTGTTGCGACCTTAAGGAGACATTTAGGCGCCCATAAAGTCGTAACAGGGTTATAGAAATAATATAGAATTAATAGGGAGGCTCCCAAACAGAGCCAACCTATACACTTTATAGTACGTTTCAAGGATTTAGTGAGATCCAGCCATTGTGCTCAATGCAGCCAAACCACCAAAGCAAACAAAGTAAAGGATAGTGCCAATCACACCTGCAACAATACCAATAATACTCCACTTTTTAGCGTCATTAGCAGCTAAAACAGCTTCATCGTATTGCTTCATCATATAAAGCTCATTCACCTTCATAGCGCGAATGATTGCATAAATACCTGCTGGCAAGCAGCAACATACAGTTGTAAAAATCGCAAGAGCCAAATTGTTATTTGGCTTAGGAGTATTCATTTCTTCCATAACTTTTTTGAGCCGACTCCCCAGGGCATTCTTTTTTTGTTTTATTATTTGAACCACGTTGCTACTATGGTGGGGAAGTCTTAAGTGACACCTCTTCACAAACAGGTTATTGTTTTCATCTATTACTTAACCGAGGACAAATTTAAGTAATTTAGATTAAATATACAAGCTAAAGAAAAACTTTTCTTTCTATCATAAACAAAAACATTACATTTTAAACAAATATAACATTTACAAATAAACCAAGAAAAGCGAGTAAACCTATATTAGTTCATCTATCCACAAATACATCAGGGATTCTTTAACATGTTAAAACAATCACAAAACTTTATACATTCTTCCCTAAGTTCATAAACAAAGTCAAATAAATCGAGAAACTTCCATAAACAATAATCGGATTAAAGTCAATTGACTCTAACCCGATTCTTTTTTATATTCTCTCAATTATTCTTCTTTACTACATGCGAATCGCGCAAGAATAAGTCTGTTTCTGATTTATGCCAAACAGTTTACACGACCTATATTGTATTCACGGATGACATTTGTCATATAATGAAACATCTTACGCATAACACTCATATTCTTTACTTTCTCTTTCATAACGTTTCCTTTCCTCTATTGAGTTATACAATCTTTTACCTATGTCCCTATTGAGACTGAAGCCCTTTCAGTGGCTACCTCTTTGTTATCCTATTGAGGTGCCGTTTGTGTTGTTTTGTGCTTGCAAAGTTAGTACACTTTCCAAAATCTCACAAAGGAAACTTACACTTTCACTTTGTTTTTCTATTAAATTTTGACCTGCGTCAATAAGATTGACACGTATCAATCCCGCTATTTGACATATATCAACCCATGCGTGCCTTTATATCAACATCCTCTAAACGAATATATTATAATAAAAAAGAAGACGGAAAGACAAGTATCACATTTTCTTTTCTTATCTTTGCACTATGAACACAAACGAAAATCATAGCTTTCGATTACCTGCAGAGTGGGAACCACAAAGCGGAGTTATACTGATATGGCCGCATGAAGATACTGATTGGCATCCTTATCTTGAGGAGATTACTGAAGTTTATCTCCAGATGGCAGATGCCATTACCCGATACGAGGCATTGCTTATCACAGCACGTGATACAGAAATGGTAAGTTCCTTACTGAAAGGAAGGCTGACAGAGGAACAGATGAAACGTGTAACGCTCTTTACTTGTGACAATAATGACACTTGGGCACGAGACGTTGCACCGATTTCGCTCATAGCAAACAAAGCATCGAAAGATAGTTCCCAGCCCCTTCGCCTACTTGACTTCTGTTTCAATGGATGGGGTGAGAAGTTTGCAGCAGAAAAGGATAATAGAATCAATCGACAACTTTACAAAGCTGGACTCCTCCAAGGAGTATTAGAAAGCCACAAGGATTTTGTACTGGAAGGTGGTTCTATAGAGAGTGATGGAGAGCGAACACTCTTTACAACAACGAGTTGTCTGATGGCACCACATCGTAATCAACCTCTCACACAAGAGGATATAGACAAGCAATTACGCCTTTTCTTCCCAAATGTAGAGCGAGTTATATGGTTAGATTATGGTCAGTTAGCAGGCGATGATACAGACGGACATATTGACACCATCGTACGTATTGCACCCAATAACACCTTATTATATATAGGGTGTGACGATAAGGAAGATGAGCATTATGAGGATTTCCGTCTCTTAGAGGAACAGCTAAAACAGCTTCGCACACTGGATGGTAAGCCTTATCGCCTACTCCGTCTTCCTATGCCTGATGCTATCTATGATGATGACGAGCGTTTGCCTGCAACACATGCAAACTTCCTTATCATCAACGGAGCAGTACTTGTTCCAACCTACAACCAACCCGAAAAGGACAAAGTAGCATTGGACACAATTCAAGAGGCTTTCCCTGATCGTAAAATCATCGGTATTGACAGCCGTACTATCATCAGACAGCATGGTTCAATACACTGTCTGACAATGCAGCTGCCAGCAAACGGATAAAACCACCTATCGTTTGAGTTGATAAAAGATGGAATAGTAATAAAAGAATACAGAACAATAAACATAAACAGGGCAATCACCTTTATTATGAGAGAACTTAAAATAGGCTTCCTACAACAACATAAAGTTGAGGATATCAAAAACAATATAGAGCGATTGGCTGAGGGAATTACAAACTTAGCACAACGTGGTGCGGAACTTGTTATCCTCCAAGAACTGCACAATTCACTTTACTTCTGTCAGACAGAGGACGTGAATAAGTTTGACTTGGCTGAGACTATACCGGGTCCCTCTACTGGCTTTTATGGTGAGCTGGCACGCGAACTGGGTATTGTCATTGTGACATCACTTTTTGAAAAACGTGCACCAGGACTTTATCATAACACAGCCGTAGTGATAGAGAAGGATGGTAGTATTGCTGGTAAATATCGTAAGATGCATATTCCAGACGACCCAGCTTACTATGAGAAGTTCTACTTCACACCAGGCGACCTCGGATTTCATCCAATTGATACAAGCGTAGGACGTCTTGGTGTACTTGTTTGCTGGGATCAGTGGTATCCTGAAGCAGCCCGCCTTATGGCATTGCAAGGTGCAGATATGCTTATCTACCCTACAGCTATTGGTTATGAAAGTAGTGATACTGACGAGGAAAAACAGCGTCAGCGTGAAGCTTGGACAACAGTCATGCGTGGTCATGCCGTTGCTAACGGTTTGCCAGTAATCGCTGTAAACCGTGTCGGTCATGAACCTGACCCAAGCGAGCAAACTCAAGGTATTCAGTTCTGGGGAAGTAGCTTTGTTGCTGGACCACAGGGAGAACTACTCTATCGCGCTTGTGACAACGATGAGGACAGTGTTATTCTCAGCATCAACCTCGACCATAGTGAGAATGTACGCCGTTGGTGGCCTTTCCTACGTGACAGACGAATCGATGAGTATGGAGAAATAACAAAGAGGTTTATTGACTAAAAACCTCCCCTAACCCCTCCAAAGGAGGGGAATTCCCCCTGCTCCTCGCCTAAACCAACAGTCATTGACCAAAGGGGAGTTGGGAGAGAGGGAGTCCTAACAGAATAAGAGATTCACGCTTTATTAATGATTACTGCTCGATAGGACTTAAACAACACCTCTTTCCATACGGAATATGATAATAAATAGAGCCTATCCGATAAGATATTAGAACTTAATATGCCATCCGCACCATTGGTGTTTACCATGAACACCACACGTGCTGAGCACCAACACATAGGCTGGATATGGATTGAGCGTTGCATTGTAATACCCAAAGAGCCATACCAAACTCATTCTTAGAGTTTGATATGGCTCTTTTTCCTTTATCAACATGATTAGCCGCTTACGCCCATTGTTGGTTTGACCATCTTTTCCTACAAAACAGATAATCCGCCCATTACTTCCCTTCGTTCTGTAACCACAGATTCAAGAGAGGAGTCGAGGGGGGGGGGTAAGGCTTTAGATCAACGGCATTCCTGCCTCTTCGCACTCTCTTCTCATTTCTTCTGGCCAGATACTTGCTTGTATCTCACCAATATGCGCCTTGTGCAACATTATCATACAAAGACGGCTCTGTCCGATACCGCCACCAATACATAACGGCAGCTTGTCTGAGAGTAACTGCTGATGAAAGAAGAGTTGCTGACGTTCTTCTTGCTTCTCTATAGCCAACTGACGAAGTAAGGCTGTCTTATCCACACGAACACCCATAGACGAAAGTTCTATGCTACGACCTAAGATAGGATACCAAATGAGGATATCACCATTCAAGCCAGTCTTACCATCTTCTGCAATAGTTGACCAATCATCGTAATCGGCAGCACGGCCATCATGCTTCTCGCCATTACTTAATCTGCAACCAATACCCTCAATAAACACCGCACCATACTTCTTACAAATAATGTCTTCACGTTCTTTTGCTGTCATTGTAGGATACATATCCAACAAATCTTGTGCATGAATAAAATGAATCGTCTGTGGAAGGAAGGGTTCCAACTGAGGATAGGTCTCACAAGCAAGGAACTCTGTACGAAGGATAGCAGCATAAATACGACGAACGACATTCTCTAAAAAGCTACGTGTTCTATCGCCTTCGGTGATAACCGCTTCCCAATCCCATTGGTCAACATAAAGTGAATGAAGGTTGTCTAATTCTTCATCGGCTCGAATAGCATTCATATCTGTATAGATACCATAGCCCGGTTGAATGTCATAGTCAGCCAACGTCAGTCGTTTCCACTTTGCCAGAGAGTGTACTACCTCAGCCTCAGCTTCTCCCAAGTCCTTAATCGGAAAGGAAACAGGACGCTCAACACCATTCAAGTCATCATTGATACCTAATCCTTTCAACACGAACAACGGTGCCGTAACACGACTTAGTCGTAATTCGGTAGCTAAGTTCTGCTGAAAAAACTCCTTTATAAGTTTGATACCCTGCTCGGTTTGACGTTTGCCAAGTACTGCTTTATATCCTTTTAGTTTTATCAGTTGACTCAT

Protein sequences of DBSCAN-SWA_3

>NZ_CP054011|894240:901584|896391_896760_-|WP_050759749.1|DBSCAN-SWA
MKCIGWLCLGASLLILYYFYNPVTTLWAPKCLLKVATGLQCPGCGIQRALHALLQGRFSEAIHYNYFLLFSGPYILSFGVRALLPKGKAKDSLTKVIEDKRLIWLYIILFFIWFIVRNILKI
>NZ_CP054011|894240:901584|900546_901584_-|WP_004360106.1|DBSCAN-SWA
MSQLIKLKGYKAVLGKRQTEQGIKLIKEFFQQNLATELRLSRVTAPLFVLKGLGINDDLNGVERPVSFPIKDLGEAEAEVVHSLAKWKRLTLADYDIQPGYGIYTDMNAIRADEELDNLHSLYVDQWDWEAVITEGDRTRSFLENVVRRIYAAILRTEFLACETYPQLEPFLPQTIHFIHAQDLLDMYPTMTAKEREDIICKKYGAVFIEGIGCRLSNGEKHDGRAADYDDWSTIAEDGKTGLNGDILIWYPILGRSIELSSMGVRVDKTALLRQLAIEKQEERQQLFFHQQLLSDKLPLCIGGGIGQSRLCMIMLHKAHIGEIQASIWPEEMRRECEEAGMPLI
>NZ_CP054011|894240:901584|895989_896331_-|WP_004360110.1|DBSCAN-SWA
MESDKVNHILMMLSSKIPAGSIPSVRTRLENTDISESEILALQSQMKDPLLSILLSIFIGSLGIDRFYIGDVGLGIGKLLTAGGCGIWWLIDIFLITDATKQKNLEQLSYYLR
>NZ_CP054011|894240:901584|896776_897055_-|WP_004360109.1|DBSCAN-SWA
MEEMNTPKPNNNLALAIFTTVCCCLPAGIYAIIRAMKVNELYMMKQYDEAVLAANDAKKWSIIGIVAGVIGTILYFVCFGGLAALSTMAGSH
>NZ_CP054011|894240:901584|899160_900045_+|WP_004360107.1|DBSCAN-SWA
MRELKIGFLQQHKVEDIKNNIERLAEGITNLAQRGAELVILQELHNSLYFCQTEDVNKFDLAETIPGPSTGFYGELARELGIVIVTSLFEKRAPGLYHNTAVVIEKDGSIAGKYRKMHIPDDPAYYEKFYFTPGDLGFHPIDTSVGRLGVLVCWDQWYPEAARLMALQGADMLIYPTAIGYESSDTDEEKQRQREAWTTVMRGHAVANGLPVIAVNRVGHEPDPSEQTQGIQFWGSSFVAGPQGELLYRACDNDEDSVILSINLDHSENVRRWWPFLRDRRIDEYGEITKRFID
>NZ_CP054011|894240:901584|895137_895884_+|WP_004360111.1|DBSCAN-SWA
MATRLKIKTTEGDIIIRLYDETPKHRDNFLKLAKEGYFNGTLFHRVIKDFMIQGGDPDSKNAPKGKMLGTGGPDYTIPAEFVYPQYFHKRGALSAARTGDEVNLEKESSGSQFYIVWGKTFKPAELKQMEHQMAMQQEQQVFNQLTREHHEEIMNLRRNRDRVGLQELQDKLIEQTKTTCKQQGKPSFTEEQIEVYTNVGGTPFLDNQYTVFGEVEEGLDIVERIQNCDTDRNDRPTEDVKIETVALL
>NZ_CP054011|894240:901584|898005_899073_+|WP_004360108.1|DBSCAN-SWA
MNTNENHSFRLPAEWEPQSGVILIWPHEDTDWHPYLEEITEVYLQMADAITRYEALLITARDTEMVSSLLKGRLTEEQMKRVTLFTCDNNDTWARDVAPISLIANKASKDSSQPLRLLDFCFNGWGEKFAAEKDNRINRQLYKAGLLQGVLESHKDFVLEGGSIESDGERTLFTTTSCLMAPHRNQPLTQEDIDKQLRLFFPNVERVIWLDYGQLAGDDTDGHIDTIVRIAPNNTLLYIGCDDKEDEHYEDFRLLEEQLKQLRTLDGKPYRLLRLPMPDAIYDDDERLPATHANFLIINGAVLVPTYNQPEKDKVALDTIQEAFPDRKIIGIDSRTIIRQHGSIHCLTMQLPANG
>NZ_CP054011|894240:901584|894240_895050_+|WP_004360112.1|DBSCAN-SWA
MAIGKWIGGALGWILSGNMLGGLVGYCIGTMLDEAFAGDNRGGDRQNGYGEQSHFGGTRPFEEDRNSFLFSMLVLSSYIIKADGKIMHSEMEYVRQFLRHNFGEQAVSQGESILLKLFDLQKQQGPYQFKETIRKSCVEIRFHTSVSQRLQLLNYLVIIAKADGIVSPEEVVALKEIALYLGLSAQDIESMLNLESGAKASSNIEDAYKVLGVSPSATDDEVKAAYRKMALKHHPDRVSTLGDDIRKAAEKKFQEINDAKERIYKARGL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004360112.1|894240_895050_+	TerB family tellurite resistance protein	A0A1V0SBY2	Catovirus	2.3e-05	50.0
WP_004360111.1|895137_895884_+	peptidylprolyl isomerase	A0A076FI46	Aureococcus_anophage	1.3e-05	32.4
WP_004360110.1|895989_896331_-	TM2 domain-containing protein	A0A1B0T6B3	Bacillus_phage	2.7e-08	50.8
WP_050759749.1|896391_896760_-	DUF2752 domain-containing protein	NA	NA	NA	NA
WP_004360109.1|896776_897055_-	CD225/dispanin family protein	NA	NA	NA	NA
WP_004360108.1|898005_899073_+	agmatine deiminase family protein	M1HH76	Paramecium_bursaria_Chlorella_virus	4.4e-44	29.5
WP_004360107.1|899160_900045_+	carbon-nitrogen hydrolase	M1H5W0	Paramecium_bursaria_Chlorella_virus	5.4e-56	38.8
WP_004360106.1|900546_901584_-	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.0e-53	38.8

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP054011|1556805:1618228|DBSCAN-SWA
GTTACATCCCAATTATGGGACTTGACTTTTTCGGTGTTCTTGACGGACACAGCCGTAAGGCTTTACGCAGTACCCTTGTATGCTCACTACCCATCAGGGGTTGCATTTCCTTGGCAATCTTGCTCTTGGTCACCCGTGCATAAATCTCGGTCGTGGAGATGAAGCGATGCCCCAGCATCTTGCTCACCGTCTCTATCGGAAGTCCGTTCTCCAGACAGATGGTCGTGGCAAAGGTGTGCCGTGCGGTGTGCGAGGTCGCTTGAGTATGCGGTAGCAGTCCTGCCTTAATACATATCTCCTGAATAGTTCTATTGAAATTACTGTTGCTGGGAAACTCTCGAAAGAAAAGCCCCTCCCTTCGTCCGTGGCTCACAATGGCGAGTATTTTCTCGGCAACGGGCAGCAACGGGACAATACTTCTGTTCTGTGTCTTTGTTCGACAGAGCGATATGTACCTACGCCCATCCCCGAATGTATAAACATCGTCCATTCGGAGTTTCTTTAAGTCTGAGAATGCCAGCCCCGTGAAACATCCCAAGAGGAAAATAAGTCTGCAATGGTTATCTGTCGAGCGGTGCGGACGGTAAGCCAAGAGTTTTTGCAGGTCGTCCGCCGTAAGTGCATTGCGCTCGTAGGTAGGCGTTTCTATGTCTATGAGTTCAAAAGGGTCTTCACGAACGTATCGCTCCTGCAATGCCTTGCGAATGACCTGATGCAAGTGGCGTAGGCGGTTGCCGACACTGCTTTCCTTGTTTCCCAAGTCCCGAAGCATAAAAAGGCGATAGTCCTCAAGCAAAGTCTTGTCCACCTCTGTGGGCATACAGTCTGCCCTGTCCCTTACTTGCAGGAAATGAACAAAACTCTTGTAGCTGTCCTTAAAAGCCCTGACAGTTGCCTTGCTTAATGTTCTGCCCTGCAATTCCTCCTTGTATTCACAAACGGATTGATATAGCTCCGTAAGTGTTGGCATGGGGCGACTTTGCTGCATATAACGCTCCTTGAGGTATTCCGCCGTGATATAGTTTTCTTCCCTTAATGTACGTTCATAGAGTGAATGCAAGCACTCTTCTATTGAGTTCAGTTGCAGATTGATGCCGCTTGAATTACCTGTTGTCGCCTTGATGCACCCTTTTCGGGCAAGCCACTCGTCGGGGGAAGTTTGCAACTGCGTGGAAAACGATGAGGACGTTCCATTACAGGTGATACGGCAACGGATTACGCATAGTCCGTCTTCATTGGTCTTGCTTCTATCTATGTAGAATAGTATGGCAAATGTACTTTTCATTGTTCTGCGGTTTTAGTTGGTCAGTTGATAATGTGCGAGTTGTGGAAGTATTTTCTCTATGTCCAGAAAGACACGCTCGGGAGATGTCTCCGCATACACTTGCGTGGTTTTGATTTGACTGTGTCCGAGCATTTTGGAAACGCTCTCAATGGACACGCCCTCCGACAGTGTCATCTGAGATGCGAAGGTATGCCGTGCCATGTGATAGGTCAGCGTTTTCTGAATACCGCAAAGCCGTGCTATCTTTTTGAGGTGTATGTTTACCGTGTCGCATCCGGGTATGGGCAGCAGATACCCCTTGGGCGGTTCGTGTCGGAAAGCCCTCGTGTGAATGCCCCGATAACGCTCGATAATGGCAGTGGCTTCGGGAAGTAGGGGGATGTGGCACACGTTGCCCGTCTTTATTCTCGGCTTGCGTATCCAAGTCATTCCCGCTTCGTGAAAGACGTGCTGCTCCGTCAAGTGATACACGTCGGTATAGGAAAGCCCCGTCAGGCAGGAGAAAAGGAACATATCCCTCGACACTTTTTCATAGCCTTGCAATTTATCTTCTCCCAAGGCTGCGATAAGACCTACCTCCTCCCTTGTGATGTAACGTGGAGTACCCACTTCCCAACGAATGGAATGGTTGATGAAGGGATAGGTGTCAATGATGTGCCGTTTATGCAGGTCTTTGAGCAAGGAAGCCAGCATGGAGAGATAGCCAGCCGAAGTGTTGAGCTTGAATCCCTTTTCTTTGGCGAAGTAGTCCTCCAAGTCTTTGATAAAGGCGATGTCGGCTTTCTGCACGGGAATATCCTCCACACGGTAGCGATACCTGACGAAGTTTGCCAGATGCTTGTGAAAGAGCAACAGGCATTTTAGTCTGCGTTCGCTGCGGTCTATGCCCACACGCTCACGGAAGCGGTCGATATACTCGTCTGTATGATGCAGCAGTCCTTGTGACTCACTGTTCAGTCCGAATACAAGCTCCCGTACTCGCTCTGCCGTGATGGGAGCATCGGATTTACCCGAAAGAGACTCATAAACCTTGTGTATGCTCACCTGAAGGCGGTCAAGTTCCTTGTTTACCGATACGGCTTCGGCACTCTTGCCCAGCAGTCGGTTTTTGCGACTGTCCCACAAACGAGGAGTACACGAGCATTTGCAACTGAACTGTACCATAGAGCGTCCTGCGCTGATGCGTCCCATGATGGGACTTTTTCCGTTTTTGTCCTGCGTACCTCTCTTGAGGTAGAAAAGCAGCTTGAATTTTTCTTTTTCCATTGTTTTTTACTTGCAAAATTACACTTCTTTGAGGAACTTTGAACGATGCAAAACATTGATAATGAAAGAGAAAACACCGTTTTAGTTACCACTTTCAGCCGTCCTTTTCCTTTCATCGTTTTTCGAACGATTTGGTAACTGAACTCCCTCCTTTTCGCTCCCTTTTCTGCCTGTTTCCTATGATGCAACCCTAAGAAGAAACAAGCAATATCCGCTGTATTTCAGTCAGATATGAGTTTTATGCCATTTTCTGCTTTCTACTCCCATACTTCCTTATAGAACGTTTGAGAAAATATCTGGTTACACACAATATGTACGGATTGCAGTACTTGCTGGCTTCCATATTCGGAGCGGTCACTCCTTTCTGTTCATGTTCTTCCATTCCTCTGTTTATCGGATTTGTAAAGGGCGGCATTCCTTTGGGCGTAACATTCGCATTTCTTATCACATCACCGTTGGTAAACGAGGTGGCTGTTGCCATGTTCCTTGGCTCCTTCGGATTGAAGGTGACTCTTATCTACGTCATCAGCGGCATTCTGTTAGGAGTAATAGGCGGTATAGTACTCGGTCGCATGCGCCTTGCTCCTTATCTGAGTGACTGGGTAAAGCAGATGCAGGCAAATTCATCCGCTCAGGCAGGGGAATGGGAAAAAGACCATACCACCTTTACCAAGAGGCTTCCCACTATTATCCGTGATGCATGGAAAATTGTCAGTGGTGTACTTATATATATTCTGATAGGTATAGGTATCGGTGCTTTCATGCATGGCTTTGTTCCTGAAGGATTCTTTGAGCAATACATGTCAAAAGACAACTGGTATGCAGTTCCTTTGTCTGTTATACTTGCCGTACCGATGTATGCTAATGCCGCAGGTATCGTCCCAGTAATCGAGGTATTTGTAGCGAAAGGCATTCCCATCGGAACGGCGATAGCCTTCATGATGGCTGTCGTTGGTCTTTCCTTGCCAGAGGCAACACTGCTCAAGAAAGTAATGACATGGAGACTTATCGGCATATTCTTCGGCACTGTGACGTTTTTCATCATCTTGTCCGGCTATCTGTTTAATTATATTCTATAATATGTAGAAGCTCCTTCCAAAAAGCATTCAAACTATATAGTAAGTCAAATCCCCAAATTTAAAAATAAAAAGATGAAAGTATTGATTCTTTGTACAGGAAACAGCTGCCGTAGCCAAATGGCTCATGGCTTTCTACAGTCATTCGACAAAAATATAGAAGTGTATTCTGGTGGAACGGTACCAGCGAAACAGGTAAACGCCAAGGCGGTGGAAGTAATGAAAGAAGCCAGAATAAACATTGCCTCACATGTCCCAACACATGTTAACACCTATCTTGACAAGGAATGGGATTACGTAATAACCGTTTGCGGTGGTGCAAACGAAAGTTGTCCTATGTTTACAGGTAAAGTAAGAAACAGGCTGCATATAGGGTTTGACGATCCCTCGGAAGCAACCGGAAGTCCCGAGTTTATTAACAGTGAGTTCCATCGGGTACGGGATGAAATTAAAGCCTGTTTCTATGACTTTTACCTGAACGAATTAAAACCACAATTAAAATAAATAGATATTGTTATGGAAAAGAAACAAGGAATTGGATTTTTTGAAAAATACCTGACTGTCTGGGTTGCCTTGTGCATCATTATTGGAATTGCCGTGGGACAATGGCTTCCGGCAATTCCGCAAACATTAAGCAAATTTGAATATGCCAACGTGTCTATACCCGTGGCAATCCTGATTTGGTTAATGATTTATCCGATGATGCTAAAAGTAGATTTTCAAAGTGTTAAGAATGTCGGCAAGCGTCCGAAAGGAATAATAGTCACTGGCGTTACAAATTGGCTGATAAAGCCATTTACCATGTTTGGAATTGCTTATTTGTTCTTCTATGTGGTTTTCAAAGCCTTTATACCTGCCGGATTAGCCGAAGAATATCTAGCCGGGGCGGTATTATTGGGGGCTGCACCTTGTACAGCTATGGTGTTCGTGTGGAGTTACCTTACTAAAGGGGATGCCGCTTATACACTGGTACAAGTGGCTGTGAACGATTTAATCATATTGGTAGCGTTTGCCCCTATCGTTGCTTTCTTGCTGGGAGTTGGCGGCGTATCTATCCCATGGGACACTCTGTTGCTATCCGTAGGGCTCTTTATTGTGATACCACTTGCGGCTGGGGTCATTACTCGAATAATGGTTATCCGCCGCAAAGGTGTGGAGTATTTCAACAATATATTTATTAAGAAATTTAATAATTACATGGTAGGTGGGTTGCTATTAACACTTATTATCCTGTTTTCATTTCAAGGAGAAACGATACTGAACAATCCCCTGCATATCTTATTGATTGCTGTTCCGCTTGTGTTGCAAACGGTTCTGATATTTTTCGTTGCTTACGGTTGGTCGAAATGGTGGAAATTACCCCATGATGTTGCCGCACCTGCCGGAATGATTGGGGCAAGTAATTTCTTTGAATTGGCGGTTGCTGTAGCTATTTCTCTTTTTGGTTTACAATCTGGGGCTGCATTGGCTACGGTGGTGGGCGTGTTGGTCGAAGTTCCGGTGATGTTGATGTTAGTAAGGATTGCCAATAACACACGACATAATTTCACAGAGACATATCATTCTTAGAGGCAATTGCATAATAAGAAGATATAATAAAGGTAAGATACCTAAATATTATGCCCCCAAAGGGCTAAACGGCTCTCAGTTATTCCCATATAAGATAGAATGTAGTCATAGGGTAGTAATTTTCATTTCTTGTTCTAACTACATTATAACCCTTTTTCTTTCACTGCCTTATCTCTTGTTGTAGTAAGTAGTAGGATAATATCGGTGAAAGAAAAAGGAAATCAATACAGATTATCAGTTATCCGTGCTGCCAAGCAGAAATATCGGTGTTATCACGGATGCAGGTTTCTGCAACCTCTCACAGAGATACTTCCTGAACAAATGCGCTTCTGTGCTGTCCAACTGAAAAGACAGGGCAATGATGATAGGAAGCGGATAGAGCGGAGCATAACCTTTTAGTTGTTCGTTTACATAAATATCATCCTCACCTGCACTCCTTTCATCGGGATGCAGGTTAGAAAATCTCATCAACGCTTGCAGTCTATGGTTAAGTTTACTCCACGTTACACCGAAGAACTTCGCAAGTTCTCCCTCCGTCATGGTTATGTCTCCGTTTCCTTTTCTGACAACCTGCATATTGCTGCCCCAATCAAAGATACTGCGATGACAGGCAGTGTTTGTTACGGCTTTTAAGTTATCGTTTGCTTTCATGCCGTTTCCTCCATTTTATAGATTGATACCTCCGAAGGTTCACAAGCCTCTCTCTCCATAGTTTCTTTATCCTTTGCCGATTGTTTGGCAATAAGCCTGTCCATATCCTCCGAAATCTTGTTGTCCGTTACCTGCGCATAAATCTGCGTGCTTGATATGGAAGCGTGCCCCATCATCTTGGCTATACTCTCAATAGGTATTCCTGCACTTAGGCTCATCGTACCGAAGGTATGCCTTGCAACATGGTACGACAATCTCTGTCTGATACCGCAAGCCTTGCCAACAATACTCAGTCTGCCGTCTATCACGCTCCGGCTGCACTCACGGGGAAAGATATGTTTTTTACCTTTTTCTTTCACCGTCTGCTGTTCTTCATTCCCTTTCTGCTCTTCCAGACAATGGCGGATAATAGCCTCTGCTATCGGGTGCAATGGTACGACAAACTCAACCTTTGTCTTCTGACGCTCCTTGCGGATATACTTCCGCCCATCCGCTGCCGTTTGGATATGCCTGTATTCCAAATTTTCCATATCAGCGATAGCCATACCTGTGAAGCAGGAGAAGACGAACATCAGCCGTGCCAATTCCGATTCTCTGTCGTTCATCGTCATTGCCATGAGTTTCATTACATCGCCCTTTTGCAAGAAGCGTATCTTCTTTTCCTCCTTCTCATACTTGGCGTTCTCAAAGGAATTGCAGCGGATAATCCTGCTGCTCACCGCACGAAACATCAGTCGGCTCAGCCAACAGAGATTGGTATTGACAGTCGATGCTTTCAGCCCACGCTTTTTTAGGAAGAAACGGTATTCCTCGAACAAACTCTCCGTAATGGTGACGATAGATATGTCTTGTACTCCTTTGTTTTCGATAAAATCTCGGAGATTTTTATCAGAATAGTAAAGGTTCAGATAAGTCCCCTCTGCCCTTGACTTTCCAACGCTTTCCTTGACGGCTTGCAGTTCCGCTTTGCTCATTGCAAGGAGCGTGGTGGGGTTAGTGGCAATGCCTTGCAAACTGTTCTTGATAAGTTCCACACTTACCACTCCGTCCCTCGTCAGTATGTCCCGATAGGTTTTTTCTACCAATTCCCTGAACTCATTGATTCTTTGGTTGGTCTTCCTATTGGTTGTCAAACCCTGTTTGGAGTTCCACTCGGCAGGCTGGCACTCTTCGCCTGTGGTAATGGCTGTGTTCTTTCCGTCTATGGTGATACGGCAAAGAATGGCGGTATTGCCGTCTGCCTTAGTTTTCTGTCTGTTGATATAGAACAGTATCTTGAATGTACTTCTCATAATGATTTTAGTTTTAATATGTCTATTGCTAAATACTCATCTGCATATCCTCCGTGAAAGAAAGAAAACGATTAAACTCCTCAAAGAGTTTTTGGGGTGTAACCTTTGCATAGCGTTCAGTCATGCTTATGTTCGAATGTCCCAGCATCTTGCTCACCGTTTCTATTGGCACTCCTTGCTCAAGCGTGATAAGCGTGGCAAAGGTGTGTCTTGCCGTATGTGTGGTAAAGGGAAACGATATGCCTGCACGAAGCCGCAGGGCTTTCAAACAGATCTGATAGTTCTTGTACTTGATACAGGGGAGTAATGTTTCCCTTCCATCGCTGTGGAGCTTCTCCATCAGCCTTATGGCTTCGGGCAGCAGTTTGACACGACAAGGCACACCTGTCTTGTGGCGGTTGAACTTCAGCCAAAGGCTACCCTCGTCGTCACGCACAAGATGGGACTTGTCCAGTTCCATCAAATCACAATAAGCAGCACCTGTATAACAGGCAAAGAGGAAAATATCCCTTGCAGTTTCCATTTCCTCCTCCAAGTCCTCAAAGTTGAGAGCCTTCAATTTGTCTAATGCTTCCTTGTCCAATGCTTTGGGCAGTCTCTTGTCGCCCTTGCTAATTTTGGCTTTGTCAAATAGAAGTACATCAGCCAATCCCTCACGGTAAGCCAACCTGCATACCGTCTTCAAATGCGTGGCTGCATTATAGAATGTGCTTTCTTGAAAACCGCACTCACCTAAGAAATACTGCCCAAACTCATAGATAAAGTTCTCTGTGAGCTGTGAGAAAGCCAAGTCTGTCACCTTGTATTTCCGTTGAATAAACTTCTGCAAATGAATTCGGGTAGAGTGATAGCCGTGTATGGCTCCTTCCTTGATGTCTATACCAACATGGCTTTCCTTCTCCTTAATGAGCATATCCAGCCTTTCAATGAGCATGCATCGTGTCTGTACGCTCCCTTGGAACAGCTCTTTCACATCGGCTGCATCAAATAGGCAACCTTTGGATAGCAGAGATTGATAAGCCGACTGAACAGACAACAGCAGATTTTCCAATTTACCGTTTATCTCCACCGCCTCACGACTCTTACCATCCATTCTGCTCTCTCGTGGATTCCACAAGTCGGGGTTGCAGGAGAGTTTACAACTGAACTGTGCAATACTCCTTCCAAGTGTAATACGCCCCATGATGGGAGCCTTGCCCGACTTGTCAAGACCGCTCTTTTTGAGGTAGAGCAACACCTTCATTTTCTCTTGTTTCATACGCTTTAATTTTTATGGGCAAAGTTACCCGAATTAAAGCGTTCCTCACTTATGCAGAAAACTGCCGACCGCAGCAACAGCCACACGAGCGAAAATAATTCAGTTACTAAAGTTTCCCACCCCTCTATTTCATGGGTATTTCAACCAAACTGCTTTGCGAATACCCATGAACGTGAGCCGTTAACACTTGTCTAAAATATGTTTACGGTTGTGAGCTTTTCTTGTTGCCTGTCTTCCAATGCTTGGACCATAATCTCAAAGTTGTTCCGCATTGCTGAGTCGGTGACTATTAACTGCCCTATCTCACTAACAGAGAACCCAAGAACGTCACAAAGAGCAGCAAGCAATCTCTCTATGCAATTCAGCACACGATGCCATAACGTAAGTGCCATGACATCATCTTCCATGTCAGCAAACAATTCACCCATGGTCTCATACTCTGACATCCGTTTTTCTAACGACATCACGATATATGTAATGTAGCAGAGCGTTGCATCAGCAATCTGACCATCAAAGTCTCTCCCCATGTATGAGCCGAGTCCGAGATGTCCTTTTGTCTCCTTGTTGACCACTTCAATGTTCCATCGTATCTGGTATAACTCGAAGGCACGCACAAAGCTCATCGATAGATCCGTACTAAGCATGATGTTCCAAGTCTGTCGACGCCCATATTTAATCAGGTATATCCTGACTGGTATATTCCCCAGACAGCCCCTCAACTCAATGTACTGACACTTGTACTTCCGGCAGCATTTGGTACGTCTTGCATACATTGCTACGAGCTCAGCAGCATTGTGTCGCTTATTCTCCACAAAGTACTTTGTCTTTCCCATCTTTGCAAGACCAATGTAGTGTATAGCTCCGTTGCCTACTCTCCTGATTTCCTCAATGAACTTCTCACAGGCAAACCAACTATCCGCCAAGGCATAATGGGGATGAATACCTCTCTTCCACATGCGCTGGAGCATCCTTATGGCGGAGTCCATCTTGCTCATACCGCATTCTTGATTCCGCTCATACGCTGGGCTCTCTTTCATGCGTCTCTTGGAGAATCTGCTGCGGAGTGCCTTCTTGCCAAGTCCGCCGTCCCCTTTCTTTCCTAATTCCTCATGGATGGAGAAGTCGAACGGCAGAGAGGACTTACCATCGAAGAACAGGCACAAAAGAAGCTTGTAGCCTAAGACATAGTTCATTCGTACATGGTCGAAAACCTTGGTAATATGCTCAAACTTCCTACCAGTCTTTTCCAAGGTTGTATCGTCAAATATAACACAGGAGTTCTCGCTCTCTGTCTGAATGCCATTCTTACGGAGAATGCATTCAAAACGAAGAACAGTATAGCTAAGCAAACGACGCCAATTCATTGCCTGCCTGACCATCATACGATAATAGCAGTTCTTTCCAGTGGTGAGAAGATGGTAGAAATTCTTCTTGTATATGGAGTGTATCGTCTCACCATTAATACGGAAAAGACAAAGGGAAAGAATCTGTTGAACAGCAGAGATACCATCGTGTTTCTCCAAAGAAAGCCTACAGAGCAGACGTCCAAAACCAAATTTTGAGAAAAGTGAGAGAATATCGCTACTCATCTTACTTTTAACACTTAAAAGCTTGGATATCTCGCTTAAATTGTCTAATTTTGCATCCATAACAGTTACTCTTTAATTTGTTGATAATCAATGTAATAAAGCACTACAAAGTTACCAATAATTATTGAGAAACTGTTATTTTAAGCCAACTTTTTGAGGGTGGGAAACTTTAGTTCAGTTACCGAACATTACTTCATCGTTACCTATGACGAAATCGGGTAACGCTTTGGTAACTGAACTTCTGCCTAAATCTGCATATTCCTACTCTTTACGAATTGTGCAGTATTATGCAAATAACTCCATTTCTTGCTCATTATCAGTCAGTTTACACCAACTTCTACTTTTCTTCCTTTTCAAGGATTAGTTGCACTTCAATTAGGCGTCTTTTAGAACCCAAAAGAGCATGGATTAATTTCGAGGTGCATGAAAATAGTTTACAAATATCTATTGATAAGGGAATAAGCTGTTTGTAAAAAATAGAAAAACATGCTAATGGATAGATATTAACCAACGAAGTGGCGGAGGCCGGGAACAAAGGTGCGGGAGACTGGAATGAAGTCATCACAACCTGAAAGACGAAGTTGATAACCGTTGGAATTGCCTTTTGCAGAAGATATGTTATTGATATTCACAAGGAAGGAACGGTGACACTGAAAGATATTATCGTAAGGGAGGTCATCTTTCAAGGCTGTCAACGTAGAACGAAGTTCGGTTTTTTGTATCTTACCTTCTTTTAGATAACATACGCAGACATTGTTTTTTCGGGCTTCAATATAGAGTAGATTGTTGATAGGTAAGGTAAGATCGGTTCCACGCAGGTTCTGATCATGCAGCGTGATAAGGATATCCTCCTGCTCATCCGTAGTCTTCTTTATCATTTCTTCCAGTCTACTATTCAACATACGGTTATAGTTTACCAACGTAAAAATAGCCGTAACGATTACCCAAACAAGGAAAGTCCAATAAAAGAATATACTGAATAGCCGCCATGTTAATGGCATCTGGAAGAAGAAAGCAGCATAGAGCGTCATAGAGATTGCTATTGCCAACTCAATAGCAATACTATAAAGAATTATATAACCATTGGTGATTGGGACATTTTTTCGTAATGGTCTTTTGAAGAAAAGGAAAGCACAAAGCCATTGAACGAAGATAGTCATGACACCAAAACCAAGACACATCAGGAATGTATTACCCCGATACTGGCTGATTCCAAAGGGTTGTAGGAGGTAAAGAAACAAAAAAATGCCAACTCCTAACGCAACACTCGTGCGCCAGGAAGTGGCATTTGTCTGTATCGTACACCTGCTATGTAGAAATGAGGTTAGTCTACTCATGATGTCTTAAATGGTTGGTTGTCCACAAAGTTACATCTTTTCCTCTTTTCGTGCAAGTGTATTTCGTCTTAAAATTTTACTCTTTTACTTCCCAAATATCGTTGGTTTCGAGCATCTCCATAAAGGTATGGTAATGCTTCTGCGCCTTCACCTCTTCTATCTGCTGATTGACAGCAGCGTCATAGGTAGGAGCCTCAACGTCACGGATAACTCCGAGGGCTACAGGGAAGCCGTCTTCGTTGCTCATCATTGCGAGTTTCAGCTGTAAGGTATTATCCTGACTGTGAGCATCATGTACGAGGATATCATCGCGAGTAATACCATTCTCACCGATTTTAACCACCTTCAAGCCAAAGCCTTCTTGTACAAGTCCAAACTCTTGGTTGGGACCGAAGATCAATGGTTCGCCATGCTTGACATAGATAGCATTCTCCTTACGACCTTGTGAGGTATAGACTGAGTTGTGACAACCATCGTTGAAGATAACACAGTTTTGTAAAATCTCACACACGGCAGCACCCTTATGCAGATAAGCAGCCTTGAGAATTTCAATTGTCTCGGTATTATCGCTGGCAACACTACGTGCAAAGAAGTTGCCACGCGCACCGAAACAGAGTTCTGCTGGGCGGAATGGGTCTTCCGTAGTACCATAAGGACTTGACTTAGAGACGAAGCCACGTGGACTGGTTGGTGAATACTGTCCCTTCGTTAGACCGTAGATACGGTTGTTCAGAAGAATCATATTCAAATCCACATTACGACGCATCGCATGGATAAAGTGGTTACCACCGATAGCAAGTGCGTCACCATCGCCCGAAACCTGCCAGATGGTAAGGTTTGGGTTGGTCACCTTTGCCCCAGTAGAGATGGCTGCTGCACGACCATGAATGGTCTGCATAGCGTATGTATTAGCATAATAAGGTAATCGGCTTGAGCATCCGATACCACTGATAACGGCTGTTTCATAAGGTGGAACACCTAACTCTGCCATTGCTTTCTGCAAGCTGGCAAGGAAGAAATGGTCGCCACAGCCAGGACACCAACGTGGTTGTCCCTTCTTAAAATCTTGTGCTGTATATTGATTCATGACTTTTATTTTAATTCAGAATTCACTGTTTGTAATTCACAATTCAGAATTCATAATTCACAATTATGATTACTTCTATTCGCTTGGGGCTATTAACAAGCATCTTGTCAACTCGTAAACTCGTCAACTTGTAAACTCATTAAATCCTTAATTATGATTACTTCTATTCGCTTAGAGTTATTAACAAGCAACTTGCTAACTCGTTAACTCGTCTACTTGTAAACTCATTAAATCCTTAATTATGATTACTTCTATTCGCTTAGCTCTTAACAAGCAACTTGTAAACTCGTTAACTCGTCAACATGTAAACTCATTAACTCATCTACATGTAAACTTCCCAACGTCGCAAGCAACTTGTAAACTCGTCTACTTGTAAACTCGTCAACTATTCTACTCAAGTATCTTCGTATAGAAAGTACCGGTTTCCTCCTTTGGTAGTGGAGCCTTGAGAAGTTTCTCAAAAGTAGTAACCAACTCCGTGACAACGAATGGTTGTCCCTTAACTTGGTTATACTGATAAGGAGCGAAGTGGTTGATACGAATACGCAAGAGGGCTGCAAGCTGACCAAGATTTTGTTCTGCAACAACGACTTTCATGTAACGACTAAGCACTTCTGCAGTGTTCTTTGGCAATGGGTTCACATACTTGAACTGTGCCAAAGCAACCTTATTTCCCTTTCTACGCAATTCCTTCATTGCAGAATAGAGATGACCGTAAGTACTACCGAAGCCAACAATAAGCAAGTCGGCATCTTCCTCGTCGCCTTGAACAACCAAATCAGGTACAGGAATACGTGCCACCTTGTTCCAACGAAGGTGGTCCATCTTGTCATGGTTCTCTGGATCGGTTGAGATAGCACCTGTCTCACCATCTTTCTCCAAACCACCAAGGATGTGTGTATAGCCCTCCGTGCCAGGGATAGCCCAGTAACGTGCTAATGTCTTAGGGTCACGTTTGTATGGAGTGTACTTATACTTCTGGTCTTCTGTGACGTAATGTGGATGGATTTCAGGCAAATCTTCGATGTTTGGAAGCTTCCAAGCAGAAGAACCATTAGCAATGAATGCATCGGTAAGGAGCACTACTGGCGTCATATGTTCCAATGCTATCTTACAAGCATTATAGGCTGCATCGAAGCAGTCTGTAGGACTTGTCGCTGCAATGACAGGCATTGGACTCTCACCATTACGACCATAAAGCACCTGCAAGAGGTCGGTCTGCTCACTCTTCGTAGGCATACCCGTTGACGGACCACCACGCTGTACGTCGATAATCACCAATGGAAGTTCATCAATAAGTGCAAGGTTCATTGCCTCACTCTTCAAACAGATACCCGGACCAGAGGTTGAAGTAGCAGCCAAAGCACCAGCGAAAGCAGCACCAATAGCCGATGCACAACCAGCAATCTCGTCCTCACACTGTACCGTTGTCACACCCATTGACTTATGCTTTGACAACTCATGTAAGATATCTGTTGCAGGCGTGATAGGATAAGAACCTAAGAAAAGACGCAAGCCAGCACGCTCAGCCGCAGCCATCAGACCATAAGCAGTAGCCTTATTACCTGTAATATCCATATAACGGCCAGGCTGTTTCACTGTTGACTCAATACGATAGGTATTAGGAACAGAAGCATGTACGTTATGACCATAGTCATATCCTGCACGTACTACCTTTATATTCGCCTCTGCAATGGCTGGTTTCTTCTTAAACTTTGTCTCAAGATAGTTGTTTACCAACTCTAAGTCACGACTGAAAAGCCAGCAGACAAGACCCAAGGCAAACATATTACGGCACTTTAGCATAGACTTATTATCCATGCCAGTATCAGCCAAACAGTCCTTCACCATCTTTGTTATCGGACAAGCCACTACCCGATCAGGGTCGATACCCATCTCGCCTAAATAGTCATCACTGCGGAATTCAGCCTTCTGAAGGTCACGCTGTCCGAATGAATCAGTGTCGATAATGATTGTACTGTTAGGCTTACAATGCTTATACTGCATCTTCAACGCAGCGGCATTCATTGCTACAAGAACGTCACAGAGGTCACCAGGCGTATAAACCTTGCCCGCACCGATATGAACCTGGAATCCACTCACACCTGTCAAGGAGCCTTGCGGGGCACGGATGTCAGCCGGATAGTCTGGGAAAGTAGACACACCATTGCCGACTGTAGCCGAGACAGTGGTGAAAATATTACCCGCAAGCTGCATACCATCACCTGAGTCACCAGAAAAGTGCACTACAACACTGTCGAGTTCTTTCACTTCGATTTGTTCTTCCATAGATTATTTCTTGTTTATGTTAGTAAATCGTTTCTGTATTTCTTAGCTTTTCCACCATAGCGGTAAAGCTTATTTAACAAACTTCTTACCATTAAGAACATAGATTCCCTTTGGCAATTCGCTCTCATGAGTCCCTATCTTAGCACCCTGCAACGAATAAATATCATCGCTTTCAGTACTTTCCTGTATCTTTGTCATTGGGACACTGATACTCATAGGGATATGCTTCTCCTTTTGATAGACACGTATCCAATCGACGCGCATCTCGTAGGTATGGTTGACATCTGCCTTTTTTGCCCATGAACCATTGCCCACTGACTGATTGAGAATCAGGTAGAAATTAGACTTATCAAACGGCCATTGCTCCTGACTATCATTCTGTTTCTTATATTGGAACACGCGCTTACCATCAGCAAAGAAGGTCAGCACGTCCTCTTCCCACTCTACGGCATAGGTATGATAACGATTCATCGACATCCAAAGATTGCCAGAATGTGGCTCATTTCCATGACTTTGTGTCCACGCAGAGTGCACGGTTGCATAACAACGCTGCTCATTATCAATCTGCTCAAAGATATCAATCTCACCGCCTTTCGGCCATCCAAACTTTGACTTTGGCATCATCCAGATAGCAGGGAAATTACCTATAAAAGGATTAACCATTGCCCGACACTCTACACGACCAAAGCGAAAGGTGAAACTCTGACTGGTTTCGATACCGCCTGAAAGCATTTCCACATCATCTTTTGACCTATCAGAATTAGGAATGGCACGCAAAACGAGATTACCATCCTTCATAAAAGCGACCTCAGGAGAGTTGCTCAAGAAGCGTGCCCATGTCACTTGGGGACGGCGCGTACAGTATCTCCACACCTTTGTATTAGGCAAGGTGCCATCCGGCTCATTAAACTCATCATGGAAGACAAGTGTATATTCTGAGCCCGGTGTTTCTGCATCCGCTGGCAATGGCTCAACACCATCAGCCAACTTGACTCCCTGTGCAAAGGATACTATGGAAAACAATGCCATTGTAAGCACTGCAAGCAATCTCTTGTTGTTCTTCTTTTGTGACATGATTTTATGAAGATTCTATCTGAAGCGGTACGATCTGAAAAGCATAGAATCATCCTATAGCACAGATGAAAACATAAGGAATTTGACATAACATAGGTCTACATTTCCCCACGTTGCTTTCTCGACTTTCCGTTTTTTAGATTATCTTTTGTTTACGTTAGTGTATTCTGAGGACAAAAGTGCGAAATATTATTGAGAAAACAAAATCTTTTGAGGAGAAAAAATATATTTTTATATCTTACAAGTAAAAAGCATCCAGAAATCAACCCTCCATTCACTTAAAAACAATAAAAAGCATATAAAATGCCAACTCATATTGTAGATTATCTTTATCAACCACCTTATCATTTCATCAACACCTAACATTAAACACCCAACACCCACCAATCAATACTTCAAAGATTCAAGATAATGTTTTGAAAAACCATTACATATTTTCAAATAAAACATCCGTATATAATGACAAATACACGTATAGAAAGCAGGTTTGTAACAAACACGGAATCAGTTAGTTATAAAGTAGTACAATAAAAGGTGCTTAATTGGATTCCAAGAGGGCGTTAATAGGACCTCAAAAGGGCACCTTTTGCAAGCCTATTAGGCGTCTTTAAGAAGCCAAAAGAGCATATATTGGTTTTAAACCGTACGAAAATAATTTACAAGAACCAATAAAATGGGAATAAATTGTTGATAGAAGACGGATAGACATAGTACTTATTTACAATCTATACATCAACAGAAGAACCTTATTAATCCTCTCCTGCCCTATTATTGATGGTTAATAAGCCCCAAATCAACACCTTATTATACAAGTAATATCAGAGTTTTATTGTAACTTTGCAATACTTTCCACAAATGAAAGCTTACAACAATAAAACAAGACATGGTCAAAGCCGTTGTTAAGGCTATCCTCAAAAGGGAAAAGGATTTGTAGAATAGCTTTCTTTTGATGAAGGAAATTGGACAAATAAAGAAACAGAAGAGAAATGATATTACTGAGCTTCGATACAGAAGAGTTTGATGTACCACGTGAACATGGGGTAGACTTCTCCCTTGAAGAGGGTATGAAGGTATCCATTGAGGGTACGAATCGCATCCTCGACATACTGAAGGCGAATAACGTCTGTGCTACCTTCTTCTGCACTGGCAACTTTGCAGAACTGGCACCAGAGGTCATGGAGCGTATTAAGAACGAAGGTCACGAGGTCGCTTGCCATGGTGTTGACCATTGGCAACCTAAGCCTGAGGACGTTTTCCGCTCTAAGGAAATCATCGAACGTATAACTGGTGTGAAGGTTGCGGGCTATCGTCAGCCACGTATGTTCCCTGTATCGGATGAGGATATAGAGAAGGCTGGCTACCTTTATAACTCTTCTTTGAATCCTGCTTTTATACCGGGTCGATATATGCACCTCACCACTCCACGTACATGGTTTATGCAAGGTAAGGTAATGCAGATACCTGCCAGCGTTAGTCCACACCTACGTATTCCGCTCTTTTGGTTGTCTATGCATAACTTCCCAGAGTGGTTCTATCTTCGTTTGGTACGGCAGGTATTGCGCCACGATGGCTATTTCGTGACCTATTTCCACCCATGGGAGTTCTATGATCTAAAGTCACATCCAGAGTTCAAGATGCCTTTTATCATCAAGAACCACAGTGGACACGAATTGGAACAGCGACTCGACCGCTTTATCAAAGCAATGAAAGCAGACAAGCAGGAGTTTATTACCTACGTAGACTTTGTCAACAGACAGAAGAAATAAGTTCGATTTCCGATCTGAACAGCAGACAGCAGGCTAAGAAACACTCCCTATAAACACCCCAACAAGCAGAATATAAGATATGATAAAACTTGCAACGGTCTCTCCTTGTTACAACGAGGAAGAGGTTTTAGAACAGTCGGCAGCACAGCTCATGGAGCTATTCGACGAACTCATCAGTCAAGGAAAGATTTCCGATGACTCGATGATTGTGTTTGTCAATGACGGAAGCCGTGACCGAACATGGGAGATTATCCAACAGCTCCACAGCCAGCATCCACGTATAAAGGGTATCAACCTCGCTCATAACGTGGGGCATCAAAATGCTATCATGGCTGGTATGATGACGGCAAAAGACTGGGCTGATGCTGTTATCACACTCGATGCCGACTTGCAAGACGACTATCAGAAATGTATTCCGCAGATGGTTGACGCCTTTGAGGAAGGCAATGAGATTGTCTATGGGGTGAAGGTTTCGCGCAAAGCCGACCCAATCTTGAAGCGTATGTCTGCACAGGCATTCTATCATCTACAAGAGAAGATGGGCGTGAACAGTATCTTTAACCATGCCGACTTCCGTCTGATGAGCCGTCAGTCCTTAGAGATACTCTCTGGATATAAGGAACGTAACCTCTATCTGCGTGGTCTCATCCCTTCTATCGGACTCAAGTCTACGACTGTTGACGACCGTATCAGCGAACGTAAAGCTGGTACTTCTAAATATACTTTGCGCAAGATGCTTAGCTTGGCATTGGATGGTATCACGTCATTCTCCGTGAAACCTATCTATTATGTTATCTATCTTGGTATCGCCTTCTTGTTCGTCACCTTGTGCATAGGTATCTACGTTATCCACGCTTTCGTCAATCATACAGAAGTAGCGGGCTGGGCTTCACTCATTCTTAGTATCTGGCTCGTGGGTGCTATGCTGATGATTTCTATCGGTGCGGTGGGAGTTTATATTGCCAAAATATATGAAGAGGTAAAACAGCGTCCACTTTATAACATCAGTCAAATACTCGATTAATCCCTTCTCACATGGTGATACGCATAAAAGAGCTTTGGCAACGCTGGAGAAAAGACTTCTGGCGACTCTTCCGTTTTGGTATAACAGGCACTATATGTTCGCTTATCCATTATGGAATCTATTGTCTCTTTCTACTCTTTACGAATACAACTATAGCTTATACAGCTGGTTACGGAGTAGGACTCCTTTGTAACTATGGACTTACAACCTACTTTACTTTTAAGGGAAAACCGTCAAAAAATAATGTTGCTGGCTTCGTTGGTAGCCACATACTCAACTATCTTTTAGAGATAGGATTGCTCCATATCTTCCTATGGTTAGGTGTCAGCAAATGGCTGTCGCCTATCCTTGTGATGGTGATAGTTGTTCCTATCAACTTCGTTTTATTACGACTTGTATTCGTGAAAGGGAAGAAGGAGCATGGGTGATGGGTGTTGAATGATGGGTGTTAATGGTTTGCAAGATTCGTATTAGGCATCCACACCATTGGTGTTAAGCATCCGCACGAGTGGTGCGGAGCGTTCGCACGAGTGGTGCTAAGCAGTAACACAGCAATAAAAAAGGGAAGAAAAAACTCATCCCCAAGCTCTTTATGATAAGAAAAGGGCTTGGGGATGATGCTTTATACCTTATTATACACTTCAAGAATCTGAGAAGCTACATCTTGATTTTCGAATCGTTTTACGTAGCGTTGACTCTTGCAGACTATCTCCTTACGATGCTCTATCGCTGAAAGGATAGCAGCGGCATTACCGTCGACATCGTCTGGACCTACATAAAGGCAATCAGGACCACCCGCTTCTTCCAAACAACTACCCGCAGCAGCTACGACTGGCAATCCGCTTTGTATGGCTTCGATAATTGGAATACCAAAACCTTCATAACGAGAAGGATAGATAAAAGCCTCAGCTTGATTATAAATAGCTGCGAGAAGGTCGTTGGGAACGCCCTGCAAGAAGTGTATGCGATTGCCAATTCCTAAACGTTTGATTTCTGCATCGAGCTTTTTCTGATACTTGGTCTGCCGTCCTACGATAACAAGATGTAAGTCGGAAGGTAGCTTTGCCATAGTACGAATACCCAAAAGAATGTTCTTTCGCACTTCTACCGTTCCTACATTCAAAATGTAACGTTGTGGAAGTTGATACTTACGACGAGCTTCCTCTATCAGTTCGGGGCTGACCGACTGACTGAACCGAGTGCTGCAACTCTGGTAGACAAGGTCTATCTTGTCCTCTGGAAAGTCACCATAATATAAGATGTCACGCTTCGTACATTCGCTAATTGCAATGATACGGCTTGCCTCGCGTAGTGTCTGATAGAACTTCCGCTTATAGAAGAAAACGTCAATAGCGGGATAGAACTCTGGATGACGTAGGAAGATAAGGTCGTGAACAGTGACAACTCCAGGGATTCCTGCTGCTGCCAAGCCTGAAGGCAGTTCACCCGAAAGACCGTGATAAAGTTCTACTCCATCTGCTTTTAGGTCCTTTACTACCCCTTTCACACGCCACCAGTCACGCTGCAGACGAAAACGAAGGTGGTCGGGATAGCAGAATTGTACGTTATCTCGTAGCTCAACTTGATTACGCAGGTCGTCACGTCCAGCATCAGGAGCATAGAGTCGTAAGTTTGTGTCAGGCATCAACGGGGCAAGGTCGTTGATGAGCGTACGCCCATAGCTACCTAATCCGGTACCATTTCTTACGATACGCTTAGCATCATAACCTATTATCTTCTTATTCATGAGCATCGGCCTTTTCTATTGGGGTGTAATCCTTTGTGCATAACTCATAACAAAGCCACAGCCAAAGAATACTGATTGGTAACGCACGGAGAGCATATTGCTTGATATATGCTTCTCGAATAAACTTTGGGAAGATGTCGCTACTACCCATACCAGAGAGCAGGAAGACAAATATCAGCAGTGCTATCGCCCACTTTCCACGCTTCCAAGGAACAGCGGTGTACCATATACAAACGCCTAACAAGGCTATCACATATCCGCTGGCTTCGCTACCTGTACTGAAAAGAATAACAAATAAAAGGACTGAAGCAAGTATTGTCTCACGGAAGGCAAGGTTCTTATACTGTGAGAAACGCAGGTAAGGAAGGGCAAAGAGCATCATTCCAGGCAGAATCAGCCATAGGTCTGAATAGTTCATACAACCTGTTGTACGACGAACAAGACCTAAAAGTGAGATATTCTGCTGTATAGAACCAAGGTTTTCTGCATTCTTTTCCACTAAACAAGTGAACCATTCGTGGTATTGTCCTATGACATACGAAGGTGAACTGATAAGCATTGGCGCACAAAAGAGTACGACTGACCATATTGCAAGCCACATCAAGAAACGCAACTTATGTCGAGAGAATAAGAAGAAAGCTAATCCTACGATGCCATATAGCTTGACCAACGTACCTAAAACGATGAAGAAAGCCGCCCAACCGTCCTTCTCTTTCTCAATAAAGAAGAAAGAAGAGAGAATCATTGCTGCCACAGCAATATTGAACTGCTGCATAAAGAGGGCCGTAGGGAGCGTTATTCCGCAGAACCAAAGTATGAATATCTTTTGTTGTTCACGTAGTCCTGAACGGATAATAGCTAAATATAGCCACGCTGTTAGGAACAATAACCACAGCAACATACCCGCCCAAAGAGGCAGAATAGCAAAAGGTGCGATGACAAGAGAGAACACCGGACCATAATGATTCACATCCCCATATTCCGCAGGATAGGCTGCATAGAGTGAAGTTTGGTTCACTGTGTGCCAATAAACACCACGGAAGATTAGGAAGTTATTAAAACTTCGTTTATACTTCAGCATTCCCGCGAGGGCAATGATAAACCATAAGCCCATCAAGAACCATCGGTTAGAAAACAGGGGATAGTTTATGAATTGTTTTATTTTATCCTTCATTACTTTTACTTCTTAGGAAACAGACAAGGGATATTCCTTTTCAACCATCTATTAAACTTCTCCACTGGGGTTCGTTTCCAGCTATGAGCACAATAATGTATGGCGTATGAAGCTGGTGTTGCCTCATACTTATTGCCTGCAAAGATTTCCGAACGGAATACCATCATATTATCTTCAAGCGGTTGGTCCTTATCCAAGTACTTGAAACCGTACTTTTCCATTACTCTTGCATAGACAAATGGAGAGATTACCCCCTTACAAACTAATCTTGGACCTTCTGGATAAATAAACTCACGCTTTTCATAGTCATCCAAGACATCTTTCACAAATTGACAGCCAGCCTCAGAACCCATCACTGCAGCCTGAATCTGTATTCCAGAGACGAAACCATCTTTAATACGATTGCCTTCGTCATCAATCATATCCATTGCACCCGTCATCTCTATCTGCTTTGGATGGTATTCCAAAGAGGTGAAGAAGTTATAGTTAAGGAATTCATCAAACGACTTCAAGACCTTCACATCAGAGTCAAGATAGATGCCACCCTCAGTGTAAAGCGCATACATACGGATATAATCAGCTGCAAAAGCCCACTTACGTTGCTCGAAAGCTTCACGTACATAAGTTGGAGCTTTTGACATATCAAAGTTCTCGGTGTTCCATAACTTTATCTCATAGTCGGGCAACACCTTCTTCCAAGTGTCCATACACTTCTGTATCTTGTCAGGATATGGGTCGTTACTGAGCCAGCAGTAATGAATAACTTTGGGTATCATAACTATAATGCTTATTTATTGATTACTTGTTTTTTTTCAATTGGTATAATGCAAATGTACAGAAAAAAATTGTATCTTTGCCCATAAGATGGAAAAAAAAGAGATATCAGTTGTTATCAATACCTACAATGCAGAGAAATTCCTGCAACGTGTACTTGATTCTGTTAAGGGCTTTGATGAGATAGTTATTTGCGATATGGAGAGTACTGACCATACCGTGGAGATTGCTCAACGTGCCGGATGTAAGGTTGTCACCTTCCCAAAAGGTAATCATACCTGCGTCGAACCAGCTCGAAACTTTGCCTTACAGAGTGCTAAAGGTCCGTGGCTACTCGTCGTTGATGCCGACGAATTGGTGACACCAGAACTGAGAATCTATCTATATCAACATATCAATAAACCTAATTGCGCGAAAGGTCTTTATATTCCAAGGCAGAACCGATTTATGAACACTCCTAAAAAAGGTTTTTCAAAGGATTATCAGTTACGCTTCTTTATTCGTGAAGGAACCTTTTGGCCTCCACTTATACATACCATTCCACAAGTACAGGGAAAAGTAGAGTACATTGACAACCATCTTTACAATGTAAAACTGCTCCACCTTGCAGAAAACTATTTGGCTGATATGTTAGAGAAATGCAATCGATACACCACTAACGAAGTCCTTAAGAAGAAAGGGAAGAACTATGGAGTTGGTGCATTACTTTTCCGTCCTTTCTGGCGTTTCTTCAAGTCCTACTTTATGAATGGAGAGATAAGAAATGGTGTCACTGGCTTCATTGATAGTGTGATGACAGGCTTTTATCAGTTTATGATTGTTGCGAAAATAATAGAATCAAAGATAAAGAAACAGACAGAAGATGAATAGAAATAAACAAAAAACTTATACAAATAGAGGGTGTAAGCATAAAAAGCATACACCCTTTATTTGTAACTAAACCTTATTTCTCCTGTACTAAAGAAAAAAAATAATTATAACTCTTATTTCATACAGTTGTAAAGTTCATAGAAGAAAATTAAGGCAACAAGTGATATCTGAATAATATTGACAGACAAATCGATTATGAGAATAACTCGACTTTCTTTCTACTACGATTAAAGGAGAATACAGCTGTCCCTCCTACTATGTGCTTGAACAGTTTTAAGCTCTTACAAAGCAATGTATAACGCACATAGTACTTAAAACCTAACATTTTATATGGAGAAGGAAGTTCTATGGTTCGAATTTCGTCTGATACCTTCTTCAATAATTTTTGTTTAAAGTCATTATCATAGGGAGAGCGCACAATATCTTTTAGTCCCTTCACTAACGAGTAAATATAAGCAGCATTAAATTGAGAGATATTATCTTGCAGAAAAGAGGATTCTTTAACCAACTTATAACGAGTTATAGTAGCTTCTATATAGTCTGTTATGTTCTGTTTCATATTACTATGAAGACAACTATAGGCATATTGCCTATAATGATAGAGTGGTGTATGTAACAGAACAACTCTATTTGCCTGGAACATCCAGGCAAACAAAGTAGCATAATCTTCAAATGCGCGATAAGGAGCAAACCGTTCTTGAGCAATATCTCTTCGAATAAGCATTGACCACAGATAACTTGTTATCTTGTCCTGAAAAGTCAAAAATAAAGCATCTTTTCTATTTAAGACAATTACATCATCATCATCCTTACTTCGCATAATGGTCTTTTGAGGATATTCTTCATAGTAATCGGACACAACAATATCTGCCTCCTGTTCCTTTGCTGTCTTGTATAATCGTTCTAACCAGCATGGCTCCACCCAGTCATCACTATCAGCAAATGCTAAATACTCACCAGTAGCCATATCCATAGCTTGGTTACGAGCAGAAGCAACACCCCCATTGGCTTTATGAAAGACACGTATTCTATTATCTTTATGAGCATAACGATCGCAGATTTCTGCTGAACCATCCGTGCTACCATCGTCTATCAACAACAATTCCCAGTCACAGTATGTCTGATTAAGAATAGAGTTTATAAGTTTTTCTAAGTATCTCTCACTTTGAAAAACAGGTGTTATTATACTTATCATCGTTTTTTATTATTTTAAGATGAATGAAAATAATCAAATTAAAGAATATATCAACGAAACAGTTTTGCAAAGTAAACCAGTCTAAGAAAGTTGCGGGCTGCCGTAAGTCGCTCAGCCTTCTTTTGATAGGTTGGTATAGCTTCTATCTGGTCAACGTTTGCACTATAATAAGTACTGTCCGAAACAGACGTATCTAAGAGGTTCTTACCCATCTTGAAATACTTAGTATTGCGGAAAGCAAAAGGAGCTAACGTTGCTAAGATATCATCATGACTTCCCCATCGATTAGTTAGCTTGTTATAAGCCTCCTTGCGTAGGTAAGGTGGGAGGTAGACATAGAGCGGAACGGAATGTTCATACCGCTTATCAATTACATCATGATTAAGAATAACTCGCACGTTATGGTCACCTGTGATAACAAGTATCGTATTCTTTGCTGCTGCAGAGGCTTTGAAGCGATTGAGGAAGTCGTTCAGTGCTTTGTTATAATAGCGGAATCCAGTGAGATACTTATCCAAGACCTTACGATTATGCTCTGCAAAACACTTCTTACCGTAGAAAGAATCGGGCAAAGGAGGAAGTTTCAAGTCCTTTGGGAACTCAAAAGGTGGATGATTTGTCGTCGTCATCACTGCAATCATCTGCCGTTTCTTTGATGGCTTATTTAACTTATCTAACAACGCTTGGAAGAGGTATTCATCATAAACACCAATACTATTATAAGTCGCATGAGGATAGTCCTTCAAAATGAAGAACTTATCATAGACTGCATCAAACTGCTGGTGAGGCAATGCTTCAGCACAGTTCTCCCACGCAGCATCCATTCCTGACATGAATGTTGTTGTGTAATTGCTGGCTTTGAAAGGTAAGGCAATTGATGTAGGAAGTGTCTTGAATCGATAAGCCGAGGCAAAGAAGCGTGGGAAAGGGGTAGAAACATAGAGGTTTTCAAGCGAAGCTACTGTACCATTCTGCACTGATTGGAAGTTACGGAAGAGTAGGTCTTCCTTGAAATGACGCTCTAAACCGAAATACATCTCCGCATTCTTTTGTTGGAGATTGAACAGATAATTGCTCCAACTCTCACTATAAATGATTACAATATTCGGTTGAGGCTGTTTCAAGCTGTCACCTACTTCCTCAAAGAGAGCATGCTGCAGTGCTCTTAGTGTGTCGTTATTCGCCATCTTCACCTTTCCGTCTGTATATAAATCCAAGGCTTCCTGCAAACTCTTGAACTTATATTCATGCAGTAAGTCGTCTGTCTTTGCTATCTTGAAAGCGTTGTTCTTCTCTTTATAAGCCTTTTTCAACATATAAATAGCATTTGGAACAAGGTCGTTCAGCAGTTTCTGGTTTGACACAAACGTGTCTTCTATCTGTAAAGGGAAGCGCCAGACTGACCCACGCAGACCGATGACTAAAAAGGTTAAATATAATAGGATGGTAGCTGATAGTTTAGTAATCTCGAAACGTGAAAGTCGCTGTCTGCTTGTCGAATGGAGAGGGTGACGAGAGGAAGACTTGCTCAACTCAATTCTACGGATAAGTAGAAGGACTGGTGAAAGAATAAGAAGAAAAGCTATAGCCTCATAGACACAGTGATATTCTTCCCATATAGTTTGAATCAAACCCATTGGTCCTTCGTTGAAGAAATCAAAGAAGGTGATATTGATATGGCTATTGAAATTGTCATAAAAGCCTATATCAATGCCGCTAATCGCCAGTAAAAGAGTGCTGATAATAGAGAAATAAAGCCTACGGAAACGACTTAACACGCATTCTGTCCATGATTTTCTAATGGCTGCAAAGATGAAAGTTAGAACCGTAGGAAGTAATAACACGTAGCATACTACTTGCAAATCAAAGCGAAAGACATTGAAGAGTAAGTGAGGAAAAACAGCCAAATTATTGCTGATAATACTCATCGGGACGAACGCAATAGCAAAGCAAATGCGTACGAAGAATAGGATAACAAGGATTACAGCGGAATGCTTTATTAGGTATGTTAAGTTCTTATACATTATTTCTTTTGGTTTATTTTGAATTTATGATAGGATAATTTCGGTAAGAATAGAGCGTCGATAGTCATTGTTTTCACTGTCATCTCTACGTCTAAAGTGCCTCATGAATAATCCCTCTCTATAGTTTAAAATCATTTTTCTTCACGATAAGAAATATTTATTTTCATGAAAAGAAATAATTATTTTCATGAAGAAAAATATTTTTTTTCATGAAAAAAATTCGCACTTGACACGCTGTTAGAATGGGCAGACACATAGAAAGGTTGAGAAAACATGGTCTTAACTGCTGTAAAAGAACTGTTTAGGGGGGTATTAAACATGATGTCTTTCAATACAACTTGTATCATGTGGCTGGTTTATCTTTTATGATTATGATGTGAGAAGAACAGCAGGATTGTATCCTTTCTGTTATGGTTTTCTAACGTTCTGAGCCCTCTCTCCGCTTTAGTCAATTGTGGAGAGATGTAGCTCTGTTATGTTCACGTGGTTTAGTAAATCATTTCCTTGCCCTCACGTAGACGTACCTTACCATCAATCTCCTCAAAATATTCATCAAAGCGAGCGCGTGTACGCTTCCAACGGTTGTGACTCCAGAGATAAATCTCTGGTTGATGACGAATTGACTGCTCAAGCTCTTTGAAGTAGAGGTCGGTGATTTCATAATCTGGTAGTCCTTTGGTCTCTTCACGAATGATGCGGAACTCACAGTTATAATGCCCACGACGCGTACGGGTCACATCACCATAGACGAAGACCTGGCTCATGTGTTTAACGATTCTTTCCCCTCCCGTGAGTACAGGGGTCTCCTGATTCATAAACTGAACCCAATGATGAATGCTCCACCAAAATGGTGCTTGGTCCGATATATAGCCCACAACAAGTGGTTTACCATTGCGCCCAAATTGTATAATTTTACGTAATGACTCTTGCATCGGAATACAAAGTGCACCCTGACGCTCGCGCACGAACTTGAAAAGACGGTCAAAGTATTCATTTTCCAATGGGTGATAAAGCTGACAGCATAAAGTGTTATTTACCCAGTAGGGGAGTGAAGTAATCCATTCCCAATTACCTAAATGTCCTAAGTAAACAGCAGCTGATTTGCCTTCAGAAAGCACTCTGTTCAGTTCTTCTGTACCTGTAAAGGTCATACGCTTCATCAGTTGCATCTTACTCATTGTCATCAACTTTAGTGTTTCAGCAATGTAATCACAGAACCAGCGATAGAAGCCTTGCTCAATTTGACGAAGTTCGTCATCTGTTTTCTCTGGGAAGCTGTTCTTGAGGTTCGTCCATATCACCTTGTGGCGATACTTCACTACTCGTGACATTAGCAGATAAAGGCCATCGGAGAGTAGATACAGCACTGGAAAAGGAAGTAGAGCTACCAGGTACCAGAAGCCGTAAGCGATGATGTAAAGGGTCTTATTGAGGGCTCTTTTCATTGATCTTCAGGGTTATTAATCGTTGGGTGCATCTTATCGTGTACCATACGATACATATACTGATAGATGATAGCTTTCAGTTCTCGTTCCATCTTTGTCTGCTCAGGCACGTGTCCGAGAAGATTGTGCTTCATCAGTGCATCGGTTACTCGATAGATAGCTTTTGTCTGTTTACCGTCCCATTGGAGTACATAACCATACTTAATGTATTGATAGATACCGTTCAGATAATTGACAGCCCAAGTCTCCTTCGCTGGTGTATGTAGTAGGTCTTTACCGAAAGCGAGGTATGGTGTTGCGTTATAGCCAATGTGAAAGAGTAGTGTTGGCATAATGTCAATCTGTTGTGCCACACCATCTACACGTCCTGGCTTTATCTCTCCAGATGGGTCATATATAATAATAGGTGAACAGAAGCCACCTATGTCGGTCTTATACTGCTCATGATCGCTCTGGTTGGTATGGTCGCTTGTTAGGACGAAGATAGTATTCTTAAACCAAGGTTGCTTGCTTGCAGACTCGAAGAACTTGCCTATCGCCATGTCGGTATAGCGGATGCACTTTTGAATAGGGAGGTGTTCCTCCTTATAGATGTTCTTATATTTCTCCGGAACAACAAATGGGTCGTGACTTGAAACAGTAAAGAGAGCCGTCATAAAAGGCTGTTTCATTTCGCCCATCTTCGCACAGTAATACTGCAAGAAAGGTTCGTCCCAGATGCCCCAGTTACCATCGAAGTCCTTATCCCCACCAAAGCGAGGGTCTTCGTCATAGTCTTGTCGACCATAGTAGTGCTGAAATCCAATCTTATTAGCAAATGCAAGGAACCCCATAGAACCACGATTGGCACCATGAAAGAAGGCTGTTTGATAGCCCCATTTACTAAGGAGTCCAGGCATACCAGTGTAGTTGTTCATTGAAGCGGGGGTGAGAATGAAGGGTTCTCCAAAGCGAGGAATACTGCAGAGTATTGATGGCATGCCATCAATACTCTTACGTCCGTTACAGTAAGAGAAGCGATAAACGAGGCTTTTATCAATGAGTTTGTCAACATTTGGTGTATACCCCTTGTATTTACCATCGAAGAAATCGCGGTTAAAGGCTCCTATATACTCACGTCCAAAACTCTCGACAATGAGAATAACAATGTTCTTCTTATTGGGAAGGCGTACGCCTGAAGCAGGATTAGGCTCCTTGTACTGCATCCAATAAACAGGGTCGTAGACCTCACGGGCAGCTGCCAAAGAGGGGAAGTAATCAGGAACGGAGAAGTCGGACTTGCCTATCGTGCGGATGAGTGCAAAGGGGGTGTTGAGCACCAAGGCGCAGTCAGTAGGACGTTCTACGTACTGGTTGGCGTTGCTGATGGTTATCGGACGCACACCCGACTGTAGTCCACCTCGACAACCAGCCACTGTAAGGACGGCAGCAACGGCAAAGCATATGAATAGTTGTGCTGCATAAACCAACCGTTGACGCAGACTCTGATAGCTGCGGTAGTCAGTACGTGGCATAACATACAGCTTATTGGCAAGCCACAGGATAAGAATAAAAATAAGGAAAAGGTACCAATGTGTAATAGCATTGTGGAACAAGATGCCAGCAATGTTGTTTTCATTATCGAACTCACGGAACACAGTGGTTGTTGTGCGGCGTAATGTGAAAGGAAAATACACAGAGTCGGCAAGGTTTATAGCAAGTGAAAGTGCATTGACAACCATGAATACCCACTTACAAAGCCTGTGATAGGCTTGGTTTTCCTTCCTCCATAGCGGTAAAAGCATCATCACGATGTAGAGAATATGCGTATAAAGGATGGCTGTTGTATCAAAGAGAAGACTTCCTCTTACCCACATCCAGAGCGAAGAAGCACTAAGACCATCAATGAAATAACTGTAATTGACAAAGAAGTATGTCAATCGTGCCACAAAGAAAATGGCATACGCCAATAGCAAGTTGAACACTAATGCTATTGGCGAACCAAATGTTGTTTTTAATAATCCCTTCATATCTTTCAATCCTGTTAGGCCTTTATATCTCCTGCATATCATGCAGTTTCTTATAGTAGCCTTCGATATCCATAAGTTCATCGTGCGTACCTCGCTCTACAATCTCACCTTCATGCAGCACGCAAATCTCATCGCTATTCTTGATAGTAGATAGGCGATGCGCCACAGCTATGGTCGTACGCGTCTTCATAAGCTTATAAAGGGCATCCTGTACAAGGCGTTCGCTCTCTGTATCGAGGGCTGATGTTGCTTCATCGAGGATGAGGATTGGTGGGTTCTTAAGGATAGCGCGGGCAATACTCACACGCTGACGCTGTCCGCCAGAGAGGCGTCCACCTCGGTCACCGATGTTTGTGTCATATCCTCGCTCACTATGCATGATAAACTCATGAGCATTGGCAATCTTCGCAGCTTCGACTATTGCCTCGTCTGTAGCATTGACACCGAAAGAGATGTTATTCTTGAAACTATCGTTGAAGAGGATTGCCTCTTGGTTTACATTACCAATAAGCTGGCGAAGGTCGTGTACTCCTAAATCCTTAATATTGATTCCGTCAATGAGAATCTCACCTTCCTGCACATCGTAGTAACGTGGGATGAGGTCGAGCAAGGTAGACTTTCCGCTACCGCTCTGTCCTACCAAGGCAACAGTCTTACCCTTTGGAATAACGAGGTTGATATCCTTCAATACCCAATGGAGTTCTGGCTTGCCCTCATCGTCCTTACCATCTGTATAAGCAAAGCTGACATGTCGGAACTCAATCTCATGTTCGAAGCTATCAATATGCACTGGTTTCTCAGGGTCATTTATCTTTACTTCTGCCTGTAGAATTTTGTCAATACGATCCATTGAAGCAAGTCCCTTAGGAATGTTATAGCCTGCGCGGGAGAATTCCTTCAATGGATTGAGAATGCTATAGAGAATAACAAGATAGTAGATGAAGGTTGGACCGCTGATAATTGGTGATTCACCCAAGACAAGGGTACCACCAAACCAAAGTACGACAACTATCATGACCGTTCCAAGGAACTCACTCATCGGATGCGCTAACTGCTGACGAATGTTCACACGCATGATGTCGCTGCGGTATTCTGAGTTGATCTTATCAAAGCGTTCGTTCATCATTCCTTCAGCACAGAAGGCTTTGATGACTCTTAATCCGCCTAAAGTCTCTTCCACCTGACTCATCGTATCACTCCACAACTTCTGTGCTGTCATACTGTTCTGCTTTAGCTTTCTACCAACAAAGCCCATAAACCATCCGAAGATAGGTACGAAAATGAGCGTGAAGAGTGTCAACTGCCAAGAGATAACAAGTAGTGTGGTAAAGTAAATGATGATAAGAACAGGGTTCTTAAAGAGCATGTCGATAGATGACATAATAGAGTTGTCAACCTCTTGGACGTCACCACTCATACGAGCGATGATATCTCCCTTTCTTCCCTCACTGAAGAAGCCAAGAGAAAGGGATGTAATCTTCTCATAGAGTTGGTTGCGAATATCACGGACAACGCCTGTTCGGATAGGAATGATTGATGCAGAAGAAAGGAAATAGGCACCAGTCTTTAGGAAAGTCATAAAGGCAAGAATCAAACCGATAGCCAACAGGACGGTTGTTGGTCCCCAACTGGTGATATATATCTGCGTGTAATAATCTGCATTGTTCGATAGTACCTCCTTGAAAGAGCCTTCGCTCCAAGACATTGCACGCGTTGCTCCCGTTCCAGCATCTACCTTAAAAAGAATCTGAAGGAGTGGGATAAGGGTTGCAAAGGAGAATATATTGAGAAAGGCTGACAATATATTAAAAATAATTGACAGCACAAGATACTTCTTATAGGGTGGTATGAACCTGCGTAAAACTTGTATGAATTCCTTCATCAACTAATCTTCTTATCTGTTTATCAATTTTGCAAATATAGCTATAAATAGTAAAACCGCAAAATTGTTTTGCGGTTTTATCTTTTTATATAAACTATATTTACACTTCTTCTCCAAAGAGTGTAGCACTGGTTGAGCCTGTAATGCGTACGCGGACCGTCTCACCAATATGATGATTGCCACGTGGCATGACTACAGCCTTGTTCTGTGGAGTACGTCCCATCAGCTGTTCACGACTACGTTTTCCAAAGCGTTCGATGAGGATATCAAACTCTTTGCCCTCGTCTTTCTTGTTCTGTTCGGCAGAGATTTCGGTCTGAAGGCGAATCAACTCATTCAAACGACGAATCTTCTCTTCCTCTGATACATTATCAGGGAGGTGCTTTGCAGCATAAGTACCTGGTCGTTCAGAGTACTTGAACATAAAGGCTGAATCGAAACCTACCTCTCGCATCAATGAAAGTGTTTGCTGGAAGTCTTCTTCTGACTCATTATGATAACCGATGAAGATGTCAGTTGTCAATCCACAATCAGGAACAAGACGACGAATAGCAGCCACTTTCTCAAGGTAGTCCTCACGAGTATATTTACGATTCATCACCTTCAGCACGCTATTACTACCGCTCTGTGCAGGGAAGTGGATATGATTACAGAGGTTTGGTTCGGTAGCTACCGCCTCAATGATATCCTCTGTCATATCTTCTGGGTTAGAAGTCGTGAAGCGCACACGCATATCTGGTACGCTCTGTGCCACCTTATGCAACAATTCTGCAAAGGAAACGCCATTCTCTGGACGCTTGCCATTAGGCAACAAGCCGTATGAATTGACATTCTGACCTAAGAGTGTAACCTCCTTAAAGCCCTTGTCGTGCAAGTCTTTAACCTCTTTCAAGATACTCTCTACATCACGAGAACGCTCACGACCACGTGTGAAAGGTACGATACAATAGTGACAGAAGTTATTGCAACCACGCATGATACTAACAAAGCCTGACACTCTATTGCCACCAATACGCTGTGGGATAACATCACGATAGGTTTCAGTGGTAGAGAGTTCGATATCCAAAGCATTCGTACCGTTCTCACACTGTGCTATCATATCAGGCAAGTTAAGATAGGAGTCTGGTCCACACACAAGGTTGGCATGGTGATTTTGAATTAAGTCGTCTCTTACTCGTTCTGCCATACATCCTAACACGCCCAAGATAAGGTCGCGCCCTTTCTTCTGTTCAGCGTGCAAAGCCTCTAAACGATTGTATATCTTGTTCTCTGCGTTCTCACGTACAGAACAGGTATTAAGGAAGATAGCGTCTGCTTCATCCTCATTCTCACATACGTCATAGCCTGCCATCTTCATGACTGAAGCCACGACCTCAGAGTCTGCCACATTCATTTGGCAGCCGTATGTCTCAATATATAGTTTCTTCATTCTGTTGTTATCTCGAAAAATTTAGCATGCAAAGATACTAAATTTATCGCATACAACCGAAAAACGTTCTGACTATTTGAGTCTTATGGCGTGCTAACACGGTCTTTTTATCTAATTAAGTCGCTTGATAAACATTTCTCATACAAGTTGAACCATTGATATTTTATTCATTTTATCATGATGATTATGACGCGTCTTACTTATATTCAACCAATGTGTTAAGGCTCAACACGAGTGGTGCGAAGGCTTAGCACAGATGGTGCGGAGGGATGAACATCCTACAGTATATCACCAACATAGGTGCAACTTATTATCAAGAAGGGCTATACAAACGGCATTTAGGTTGATCAGATAGTAAGATTTGCAAAACTTACAAACTCGTTTACGCCCTTTATCGGATATTTTCCGTACCTTTGCAGACCGATTAGACACATTCACAATAAATAAAGGATAGCTACAGGTCAGTGAAAGCATAGAGATAAGTAGGCTAAAGGTTACTGATAAACTCAATGTCTGATAACTGTCTGGTAATGAAAATAAAACAATGAACAAGAATACAAATGATTTTGAGATAATGGCACCTGTAGGCTCACGAGAGTCACTCGCAGCTGCCATCAATGCCGGAGCTAACTCTGTTTACTTCGGTATCGGAAAGCTGAATATGCGTTCACATTCAGCTAACCACTTCACCATCGACGACCTTAAAGAGATTGCCGAGACTTGTAACGCAAAGGGAATACAGACTTATCTGACTGTAAACACTGTCATCTATGGCGAGGATATTGAGACAATGCACGAGATTATCGATGCTGCTAAGGCTGCAAATATCACCGCTGTCATCGCCAGTGACGTTGCTGTAATGATGTATTGCCGTCAAGTGGGGGTTGAGGTTCACCTCTCAACACAGCTGAATATCTCTAATATTGACGCCCTGAAGTTCTACGCTCAGTTTGCTGATGTTGCCGTATTGGCACGCGAGCTGAATATGGATCAGGTGAAGGAGATACACGAACAGATTATCAAACAGAATATCTGTGGTCCAAAGGGGCAGCCTATTCGTATCGAGATGTTCTGCCATGGTGCGTTCTGTATGGCGATTTCTGGCAAGTGTTATATGAGTCTTCACGATTCTAACCGCTCTGCTAATCGTGGTGCTTGCACCCAGATATGCCGCCGTAGCTATACGGTTACAGACAATGAGACGGGCAATCAGTTAGAGATTGACAACAAATACATTATGAGTCCTAAGGACTTAAAGAGTGTTCGCTTCATTGATAAGATGATGGATGCGGGTGTACGTGTGTTCAAGATTGAGGGGCGTGCACGTGGACCAGAGTATGTTCACACCGTTGTTAGCTGCTACAAGGAGGCTATCGAGAGCGTACTCGATGGTACCTTCACCGAAGAAAAGAAGGACCAGTGGGACGAGAGACTCTCAACAGTCTTCAACCGTGGCTTCTGGGATGGCTACTATCAAGGTCAGAAGATGGGCGAATGGACAAAAGATTATGGCAATAAGGCTACCGAAAAGAAGGTACTCATCGGTAAGGTGATAAAGTATTTCTCTCGTCTTGGTGTGGCTGAGGTGGCTGTTGAGGCTAACACCTTCGTAAAGGGAGAGAAGCTTCTTATCACTGGTAACAGCACTGGCGCTATGTTCCTCAATGCTGAAGAGATTCGTTACGACCTCAACCCTGTTGATAAAGCAGAACAAGGTTGGCGCGTTTCTATCCCTGTTCCTGATAAGGTGCGCCCAAATGATAAACTGTTTAAGCTGGTAACAAAGTAAATTTGAGTGAACGAGTAGACAAGTAGACGAGTAGACAAGTGGACAAGTTACTTGCTTATATAACTCTACTCACAGAAGTTTTCATAATTCTGAATAGAACAAAACATTTATACAATGACAATAAACGAAGCACAAGATGCGGTAATTAGTGAGTTCGAGGACTTCACTGATTGGATGGATAAATACCAAATGCTCATTGACTTGGGTAACGAGTTGGAGCCATTAGAGGAGCAGTATAAGAACGAGCAGAACCTTATTGATGGTTGTCAGAGCCGTGTATGGCTGCAGTGTGACAACGTAGATGGTAAACTTATCTTCACTGCTGACTCTGATGCACTCATCACAAAGGGTATCATTGCCCTTCTGATACGTGTATTGAGTAATCATACTCCACAAGAGATTATCGATGCTGACCTGTATTTCATTGACAAGATAGGTCTCCGCCAGCATCTCTCACCTACACGTAGCAACGGCTTACTGTCTATGGTGACAAAGATTAAGGCGTACGCTGTAGGGTTTAGTTTGCAGTAAGAAAGCCTCCCCCAACCCCTCCGAAAGGAGGGGAGTGCAGATAATAAAGGGATAATAATACAGGGATGCTTTGTTGAGATATCTATAATATTTAGCATATATCCCTATTCTATAATAATATTCTACAACTATAACCCACACACAAGCTAAGACTCCTCCCCCTTCGGGGAAGTTAAATGGGGTTCTACAAGCTAATATTCCTCTCTTCGGCGAGGTTAGGTGGAACTTCACAAGCTAAGACTCCTCCCCTTTCGGGGAGGTCGGGTGGGGCTTTTCCTTATGAGAAAACTACGCACAATCGAAATGAATAGGCTTTCCCTTGAAGAATTCAAGGAAGCTGATAAACTGCCACTCATCGTTGTGTTAGACGATGTGCGGTCGTTACATAATGTGGGAAGTGTCTTCCGTTCGGCTGATGCTTTCCGCGTGGAAGCTGTCTATCTATGCGGTATTACCGCCACACCTCCTAACGCAGAGATTCATAAGACCGCACTCGGTGGTGAGGACTCAGTTGACTGGCGTTACTTTGAACGTACAGAAGATGCTATCGAAGAACTCCATCATCAAGGTGTATTCGTGTATAGCGTAGAACAAGTGGAAGGCTCAACAAAGCTGCAGGAGCTCAACACAGAGAACCCAACCAACCATCAACACCCAACACCCAACACCCAACACCCAGTCATCCACTACGCTATCGTGCTGGGCAACGAGGTGAAAGGTGTAAAGCAAAGTGTCGTGGACATGAGTGACGGCTGTCTTGAAATTCCACAGTTCGGCACCAAACACTCACTGAATGTAAGTGTAACAACTGGTATTGTCATTTGGGAGTTTGCGCGTCAGCTACTTATAAAGTAGGTTTCAAACAACTGACAACATAAGATATTGGGGGCAAATATGCCCCCTTTTTAATTTTAAATCACATGAAAATAGCCTGCATAAGTGGGAATAAAGCAGTAGTAGAGTTCACCTTCTGCGAATTATTTTCATGAAGAAAAATAATTATTTACGTGAAAAGAAATATTTATTTTCATGAAGAAAAAGAATTATTTTCATGAAAATAAATTATAAGCCTTGCAATGTTTGACCGCTTATTATTGTGAATAGGGTTTGTTAATACGCATACTTACACTACACTTCATGGTGTATAAATCCTTAAAATCATATTTTTACAAGCAATCTTCTTGCTTTTTTTTCAAATATTACATACCTTTGTGAAATCGAAATCAATGTAGAAGGATGGTATCATATTAAAGCTATGATATCTAAAAACGACCTAACTTAAAACTAAAAACGAATGGATTATGAAGAAGGTATTATTGTATCTACTTGCTTTACCAGTGATTATGTTGCTATTGGCAAGCTGTCATTCTGAAGAAGACGACTTTATTGATAAGCCAGATCCTAAGAGTTTGATTATTAAAGGGGTTGCTAAAACGCCAGATGGACAGCCAATTCCTAACATAGAATTGAAGTTGGACTACACGATTATGTCTGCTCTTTATTCTATTAAGGTTTATCATAAGGCCAAAGCAACGACGGATAAGGATGGTAACTACATAATGTTTTTCAACTTAAACGACAAAGAATTAAAGTCTTTAACCACTTATTCACCTGAAGAAGGCTTCGTATACCATCTACAGATGACGTTGGATTTGAGTAAGTTGGATGACAAAGTGTATCTATTACCTACTGATATCACAGCAGTACGTCCGTTGAGTGAGAGGAAGCTCTTCTATGATGCTTATGGAATGCCAGGTCGTTTACAGCAAGGACAGGTGTATGAACAGAATATATTGATCCCTCGCAAGCAGCTTGCAAAGGTAAGGATAGAAACGAATGGAGCTATTAACGAGAAGGATAGCTTTGCCATTTGTAATAAAGTCAGGTATGGTATAGAGAGCCAAATACCGAATGGGTTTAATGGAGAAAGAGGTTATCTAATGTTTTACCAACCCATAAAACTGAAGAATACACATAGTCAGACGGTGCAGATCTCATGTGCTGCTGAGGAAGACAGTAAGCTTAGTTTGTATCGTCTACCAGATGGAGAGTTTAATTATAAGGAGTATTCTTCGGAGGTTGAGGTCCCTGTGATGCAGGCAGGAGGTGAGTTGATACTTAGAACGCATTAGGCTTATTCTGTGGCTGTTAAGTCTTAGTAGGGCTACTCTCGTGGGTATAGAAACAAAAATAGGGGCTGAGTGCTCAGTCCCTATCACCTTGTTTTATATTTGTCTTAAATAGCTCGAAGCACCACAGCAATGGTCTTCATACGCACATAGTTCTCACTTAAGAACATAAAACCATGGTAGCGATTGGCTGTTCCCCAACTATTCTTGCAGAGGAAGAAGCGTCGACCATGTTGGTCGTGAGCCAATCCAACGATTTCCATGACATGATCATCGGTTGTACGATGCGCTTCAAAAGAAGTCTGTCGACGCTCGGCAGTCACCTTTTTGTCTTCATTTTTCAACACAGCAAAGCCATTTCCAAATAAGAAACCAGGCTCTGATATGTCACCTTCCCAGCACACAGGATGTCCTGCTCGTAGACTCTGAACAATGCGATTCATCATCGTGTCGAGTGGAACATTGAGGAAAGTGTCATGAAAGTAATTATCAGGTACTTCCAAAGGGAAGCGTTGTCCGTATGGATGATGTGTGAAACTGGTTAGTGCTACGTACTCATCATCAGTGCATACGCTATGTGCAAACTCTAATGGAGTGTATAATGCGCCTAATATAAAGACCTGTTTAGGTAGCGGACCGATATACTTATCCAATAGTTTCTCCGCATCATTGCCCTTATCCAACTTACGACAAAGAACGTTATAGTCCATATCTGGCTTATGACGATACGCATCATAATGCTGCAAACCATAGGTTTGTATAAGGTCGAGTGCCATAGTACACATGCCACGCGTTGTGATATCAGCCTCCTTCTGAACGACCTTATTAGGGAGTAAATGACGACGATTTGCCTGCTCACTAAGATACATACGTGCCACATAGTCAGGACTTAGGTTTATAGAATCACCCCGTATAATATGCTCTGTCTCAAGGGTTGCAAGCATGCCATAGACCCAGCAGAGCGAACTCAACCCTTGACCCTTCACTGGAGTAGTAGGAAGACGCAAGTCGACAGTGAACTTCTCTTCTGGAAAAGAGATGTTACTCCGTTGCTGCCCACAGCTTACTAACACTAAACATGCCAAGAATATAAAGATACTTTTCTTCATTCTTCAATTCAATATTACCGTTTCTGTCTTGCACTTGGTTGTAGATAATGCTGCATTATCCCATAACCAGCACTAAAAACAATCGCTAAGTTAACTATAGAACATTTGTCTTAACTCCTCTCACTCCCTTTCACTCCTTAACTCCTTAACATCATCTCTTGCTCAATACTCCACCATCTTGGTCCAAGCCTCAGCCACTTCCTTGTCTAATGGTGGGACAACAGCAGGGATAGAGAAGGTCCAAACGCTGTTCTTCTCTTTCTTAATACGTTTGAGTTCGCTCTCAGTAATGGTCATACGGTCCGACACATAAAACTCACTCCAGACGTCAATTCGCTCGTCATCGTCCTCTCCACGGTAGTGAGCAAAGAAGGTTTGATGCTTCTGTGAGGCAAGGAGAAGATTGTTAGAGAGGTAACTCTCGCTCTCATCATACTGAGTCATCCGAGCCACGATACCATACATACGCAGCTGACTCATGTCTATTTCGTGCTTTGGTTGACCAACGAGTTCGTCCATCTCAAGGGTTGTCACAACCTCTATCTTCCCATTAATCTTCCGCTTTTCCTTGCTTATCTTACCGCATTTATCAGCCCATCGGTACACATCTCCATTGTTACGAGTGGAGTATTCCTCGCTGTCAATACTCTTAAGGAGCGTCTGCCGTTCCAGATTAGGGAGTGAAATGCGCACAAAGGTATCATCACCATTGGCTTTCGGAGCCTTACGACGACGTTCACCAAGAAACTTTCGTTCAACAAAAGGCGATCCTTTCTTCCCTTCTGAAGCCTCAATAGCAGTGTCAGAAAGCGGTATATAAAACTCCATCATACCGTCAATAAAATAGCTAAGCATGGAGTTTGTGCTCTGATAGACACGATAATAGCCTTTCAGACGAGTGTATTGTCGTTCCTGCGCCTGCGTATTCACGACCGCAAGAATGAGTATTATGGAAAGCAAGAAACTACGTTTAAACATTTCTTTTTGTGTTTATATGAATACAAATCATAGGTATTCCTTCAAGATTCCCCACACGGCTATGATATGACAAATACTACCTGCAAGGACGAAGAAGTGGAATACTGTATGCATATACTTACGTTTGTTGAGCGAATAAAACAATGCACCAGTGATATACATGACTCCTTCTGCAAAGATCCAGACGAGCGATTGCGTTTCCAAAGCATCGACTAATGGCTTGAAGGCGACCAATACTGATAGCCCCATACCGATGAATGTCAACGTTTCTAAGTTACTATGGTCACGCAGTTTACGGAAGGATGAGATGGTGCCGAGTATCGCACAGAGCCATACAAAGGCAAACAAACCCCAGCCCCAAGCACCTTGATTGCGCAAGGCTATCAGTGTTATGGGCGAATAAGAGCCTGCGATATGCCAATAAATGGCTGCATGGTCCCACTTTCGCAAGCGTTCTTTCCATACAGAATGAGCAGAGAGGGCATGATAGACAGTCGATGTGATATAACTGAAAAGCATCCCGACAAGATATAATATCACACCCGCTGTTGCCCAACCAGACCGCTCCTTAGAGCACCAAACAAGGAAAATCGTACCGAACACTACGCCCAGTACGATTCCTCCACTATGACTCCATGAGTTCCATAGTTCCTCTTTGTGTGAAAAGAATATCTTTCGTCTCACCTTGATAACTACTTTCTTCTGCGGCTCTTGCTACCACGCTTGCTGCTCTTTCGGTCGTTCTTCCTATTTACAGCATACTCAGCAGCGGTCTGCTTTGCCTTTAATGGGCGACCATCATCAAGTGCGAAGTCGAGTTGTCTACGCTCTAAATCAGCCTTAGCCACCTGTATGCGGATAGGATCACCAAGTTGGTAGACGTGGTGACGACGACGACCAACGAGACAATAGTTCTTCTCGTCGAAGTCGTAGTAGTCATCATCGAGGTCACGCATTGGTATCATACCCTCGCAATGGTTCTCGTCTATCTCCGCATAGATACCGAAACTCTGAATACCAGATATGTGTGCATCATAGCATTCACCGATATGCTCGCTCATAAACTCAACCATCTTATACTTGATAGAGTCACGTTCTGCATTCTGTGCAACGAGTTCCATGTCTGAACAATGCTCACAAAGTTCCTCGTAATGGTCCTTATTAGCCGAGCGACCACCGTTCTGGTAGCGTGTTATCAAGCGATGAACCATCGTGTCAGGATAACGACGAATAGGCGAAGTGAAGTGGGTGTAGTAATCAAAAGCAAGTCCGAAGTGACCGATGTTATGCGTAGTATACTTCGCCTTCATCATCGAACGGAGTGCAATCGTCTGTATCACCTTCTCTTCACGTTTGCCTTGTACCTCGTCCATCAACTTGTTCAACGCACGAGCAGTGGCACCCTTGGTGCTGGCAGACTTGAGTTTATAACCAAACTTAGCTGTAAATTCACGCAAGTTCTCGAACTTCTGTGGGTCAGGATTGTCATGAACACGATAAGGAAGGGTCTTTGCTTTCTTGCCTTTCTTCACGATTCCAACGCTTTCTGCTACTGTCTTATTAGCCAAGAGCATAAACTCTTCAATCAACTTGTTGGCATCCTTTGATCGTTTAAAGTAACAACGGATTGGCTTACCCTTCTCATCAATGTCGAAGTGGAGCTCTTCTGAATCGAACTTCACACTTCCTGCCTTCATACGACGACCACGAATCAACTTTGCAAGACGGTCGAGTGTAATGATTTGCTCGGCATTCTCGCCTTTATATCCTGCCTTTCCTGGATTTGGAGCAGGCTCGCCTGTACCATCAATAACACCGTTGTCTTCCAATATCTGCTGTGCCTCTTCGTAGGCATAACGACGATTTGACTTGATAACCGTGTGCACAATGCGGTAAGCCTTTACGTTTGCTTCATCGTCAAGGTTGAATATACAACTGAAAGCAAGCTTCTCTTCATCTGGACGGAGCGAACAGATAAAGTTACAAAGACGCTCTGGAAGCATCGGAATAGTGCGGTCTACGAGATAAACTGACGTCGCACGCTGTTGGGCTTCACGGTCGATAATATCGCCTTCTTTGACATAATGTGACACATCCGCAATATGTACGCCCACTTCCCACAGTCCACTCTCTAACTTTCGGATAGAAAGTGCATCGTCAAAGTCCTTCGCGTCACGTGGATCAATCGTACAAGTCCATACGTCACGGAAGTCTTCACGTTCCGCATAGTCCTGTGCTGTGATCTCAGCACTTATCTTCTCGGCAGCATCCTCGACACGTTTAGGATACTTATAAGGCAAGCCATACTGTGCAAGGATGGTGTTCATCTCTACATCATTGTCACCAGCTTCACCCAAGACGTCCACCACTTCGCCCACAAGGTTCTTATGGTCGGCATCAGGCCACTTCGTTATCTTCACCAAAGCACGGTCATCTGTCTTTCCTCCCTTTAGTTTCTTCTTAGGAATAAGAATATCGTGAATAAAGAGATTCTCCTGTGTTACAAGAAAGGCAATGTCCTTCTCGACACGCAACCTTCCTACGAAGGTGTCTTTCTTCCGTTGCAGTATCGCGATGACCATTGCCTCTTTTATATGATTCTGACGGCGTGCCATGAACTGAACTCTCACTTGGTCGCCATTCAAAGCCGCCATAGAATTACGCTCAGAGACAAAGACTGGTGTACCACCATCCTCTGGCAGGAATGTATTCTTACCATTCGCCTTGCGGATAAAGGTACCTTCCTGCACCTGTCCTTTGGTATTCAACGTGTAAGCACTCTCTCCAACCTTTGACAGGAAGTCGTCCCACGCCAATTCCTCCATCACATCTATCGCCAACATTTTGGCTGGATGGGTGGTCAACTTGAGTGCATGAAATATCTGTTTAAAGCTAAATGTCTCGTCGGGTTGTGTCTGAAAGAAACTCATGAGTTTCTCTGCAAGCTGCTTCTTAGTCAATCGCTTGCTGCTTTTCTTTTCTTTCCTCATAGTGGAATTAGTTGTTTTGAACTCAAGTAAAGGTTATCCTAAGCAGTCTTAAAAGCCATCGGACACCATTGTCCGAGGGCTTCGGACAAGTCGTCCGAAATAGCCGTAGCATGTGTCCGGTAGACCGAGACAAAACGGTTTGATACTTAGTTGCAATGCTGTTCATTACATACAAAACATCTAAAAACCGAAACTTGAGTTTTGTTATTTTCCACAAAGTAACGAAAAAGTTTGTATCTTTGCAAACGTTTGCAACGAAATTTTTAATGAAAAAGATACTTATAACAGGCGCATCGGGCTTCATTGGCTCCTTTATCGTGGAGGAAGCACTGCGCAGGGGTATGGAAACTTGGGCGGTAGTACGCCGTACTTCCTCACGAGAATACCTCCAGGATGAGCGGATTCATTTCATAGAATTAGACTTCTCATCTGTCGATAAACTAAAAGAACAGCTCTCTGGACATCAGTTTGACTATGTTGTTCATGCCGCTGGTGTAACAAAATGCTTGAATAAGGAGGATTTCTTCCGCGTCAATCGGGATGGTACGCGCAACTTTGTAGAGGCTCTTCAAGCACTTAATCAGCCTTTGGAGCGTTTTGTTTTCCTATCAAGTCTTAGTATCTTTGGCGCTATCAGAGAGCAACAACCTTATAAAGAGATAGAGCCAACAGATACTCCACAGCCTAACACAGCCTACGGTAAGAGTAAGTTGGAGGCTGAACAGCTGTTGCCTTCGTCCTTTCCTTATATCATCTTGCGCCCAACTGGCGTTTATGGACCACGTGAGAAGGATTACTTCCTGATGGCGAAGAGCATTAAGGGGCATAGCGACTTCGCTGTTGGTTATAAGCAGCAGGATATTACCTTTGTATATGTTAAGGACGTGGTGCAGGCTACCTTCCTTGCACTTGACCACGGAAAGATAGGCAGTGCCTACTTCCTAAGTGATGGAAAGGTCTACCAGAGCACTACTTTCAGCGACCTTATCCACGAGGAGTTAGGCCGTCCTTGGTGGATTCGTATCACAGCTCCGATATGGGTATTACGTGTTGTCACGTTCTTTGGCGACCTTATCGGACATGCGACAGGTAAGATTTCGGCTTTAAACAACGACAAATACCAGATTCTAAAGCAGCGTAACTGGCGTTGTAACATCCGTCCCGCGATTGAAGAGTTAGGCTATAAGCCTGAATATGACCTCAAACGAGGCGTGAAAGAGACAATTGAATGGTATAAAAAAGAAGGCTGGCTGTAATTTAGCTAATTATTATTAGCCTTATTGGCCCAATTAGGCTAATAAGGCTAATAGGCCTAATAAGCCCAATAACAACAAACAATGAAACAATTCATCATAGACTTATTTAAATTAGAAAAGAAGCCCGTAAAGGGTCTTATGGCATACGAATGGGTGGTAATGGCTTACTTAGTGCTGACACTCATCGTCATCTTCTTTATGTACACCACCATTAACAACCCGCAGGCAATGATCTTCGGTCGTCTACGCATCGTCGCTTTGACGGCTGCTATGTGGGTGGTTTATCGCTTAGCTCCCTGTAGGGCGACTCACTTCCTACGTGTTGGCGTACAGTTAGGACTACTTGCTTGGTGGTATCCTGACACCTTTGAAATCAATAGACACCTGCCCAACCTCGACCATCTCTTTGCGCAATGGGAGCAAGACCTCTTTGGTTGTCAGCCAGCCCTACTCTTCTCAAAGGCTTTGCCGGGACATCTCTTCAGCGAGTTGTTCGACATGGGCTATGCTGCCTACTATCCAATGATAGCCGCAACGGCTGTTTATTACTTCGGGTGGTACTATAAGGAGTTTAATAGAGCTACCTTTATCATCCTCTCTTCCTTCTTTATTTATTACATCGTATTCATCTTCGTGCCTGTAACAGGACCTACCTTCTATTACAAGGCAATTGGTTTACAGAACGTGACAGCGGGTATCTTCCCTAATGTTCACGACTACTTCAACCATCATCAGGAGTGTTTACCAAGCCCAGGATATACTGACGGCATCTTCTATCACCTCGTTGAGGATGCTAAGGCAGCTGGTGAGCGTCCTACTGCAGCCTTTCCAAGCTCACACGTTGGTGTCAGCACCATCTGTATGTTACTCCTTTGGCACGATCGCAACTATAAACTTTTAGCTATCCTTGCACCTTTCTATCTTCTGCTTTGCTGTGCCACTGTTTATATCCAAGCGCATTATCTCATTGATGCCATCGCTGGTTTCATCACTGCAGTTATCCTCTTTGCCATCCTCCTACGCATATCACGTAAGATGATAACGGCGTAATGCTACACTATGGATAAGGAATAAGACTATAATAAAGTCGATTAAAGGCGTCAAGCCAATAGTTTCTTCGTATAAGAAAAGTATGTAATACGATAAAAACTATTGACTTGACGCCTTTTATTTTATGCCTTCTCTGATTTTTAAAACATCATTTTTCGTTGAAACCACTTGGCAAACACAGGATCAGTAATAGCCAACTCCATCCCACGCTTTTCTATCAAGTCACGATCAAAGAGTGCTTTCTGCAATCGGCTGATATTCGAGTAACTCCCCAATTGATATTTCTCTCGTATCTTTGCAAGTCCAAAGTTTTTCGTTACACCAGAGCATAAGGCACGTAGAAAGTTAAGTTGATACTCCGAGAGGGGTTCAACCATCTGCATAAAGAGTACCTCATTTGTCGCTAAGAGGTCATCTGTTGCCTGTTTGATATCGATCTCATCCACAGTCTCTCCTTCCTCCTTCTGTGTATAAACGAGCCAAGATAACTGCTGAACATAGGCTGAATAGTTGTCGGTGAAGCTGCATATCTCCTCCGCAAGGGCTGAACTGATAGTCCTCTTACCATCTGCAAAATGACTGACAATATACTCCACCCACTCAGCCGATGGTATCTTGCCGAGTACTATCAAGTCGCCAAACTGATAGAAAGGCATACTGCGGTGTAGAAAGATGCTACTCATCAAGTGATGCTTACTACCGAAAAGACAGTAAGATACGTGCTTCTGATGTTGCCATACACTCCTTAATCGTGCCTGTACATGCTTGCTATCGGTCATTTCACCTATCTGTTGGAACTCATCAATACAGACAACAATCTGCTTTCCTTTCTTTATAGCAATCTTTTCAACCATCTCAAGCACTTCTTCTGGCGTATGTGTCTTCGGAGTTATACCCAAAGAAATAGCAAAATCACTATTCGGTTCGGGACTAAATGATATCTTTGGCGTAAGTCTATACAAGAACTCCTTTGCCTCCTCGAGCCACATACTCTGCTTTGATGCCGTCTGCTTCAGTACTTCTGATGCCAAACGGTTGTAAAAGTCATATTCGCTCTTACAACCAAAGATGTCTAAATAAATCGTTATAATATCTTCTGACTTCATCTTTTCACACACACGCATCACCAAGGAGGTCTTTCCCAGTCGACGAGGAGACATCAGAATGGTATTGATACCACCTCTGAAATTATTCATCAATCGGTTTGTTTCCACTTCTCTTCCTATGAAGTTATAATCGGAAACAGCTACTCCATAAACAAATTTCTTGCACATAACGATTACGTTTTAGCTTGTCTTACGACTGCAAATATAGTAATAAAATAGCAATCACACAAGTTTGTGTGACACAAACTTGTGTGACACAAACTTATGTGACAAATAACACGCTTACAAACAAGCATTTATAAGATACAAGGAAAAAGCGATATCAAAAACACCTTGATATCGCTTCTTTTTTTATGCTCTTTTTACGTAGAATAAACATGTGGGAAAACAACATTCTACGCATGTTTATCCTACAGAAAGGCCGCAACTACGAATTCTTTTCATGAGCGAAAAGAATTATTTTCACGATAAGAAATATTTTTCTTCATGATAAGAAATATTTATTTTCATGAAAATAATTCGGAAATAGGACTACATACCAGTGCCAGCACCCATTCCAACACCATTCATTTGTTGGTCATTCTTCTTCTCTTGGAAGTCATTTGAAATATTACTCTTGTGTGTTTGGAACTGCTTTTTAGTGTTTCCAAAGTTCCAAGTGAGGGTTAATGCCACGTGTTGTGCTGGTATCGTGATATTCATGTGGTTCTCAAAATTAGCACCATGGCTGTATTGCTTGATGTGCATCTTTCCAGTCAAAGGTACAAAGTACATAAAACTAAGGTTGAGTTTGTCCTTAATAAAACTCTTTGAGAGGGTTGATGTGAACATATTAAAACCTCCATTATGTCCCTGCAATAAGTATTTCTTTGTCAGTCCACCCATAAACACACTCCAATTTATCTTCCATGGGAAGGTTTGTTGTACGCCCAAGAATGCACTTGCTTGCCAGCCGTGGTTGTATTCGCCCAACTGCTGGGAACGAATATCTCCATAATCAAAGCTTCCATTGAGCATGATACGTGTCTTAGGGGTGACAGCATAGTTCATAAATGTGCTGAAATTGGTCCAACGGCTACGTACGATATTGCCGTAGGTAGTATTCAATACAGTTCCGTTCATAAACGAATACTGCTCAATTTGATTGTTGGCAAAAGCTTCACCGAGTGTCATGTTCATCATAAACTTCGGTGTAAAGTAATTGAATACTAAGCTAACGTTGTGGCTCTTTTCAACCGATAGGTCTGGATTACCATAACTCAAGACCGTTGGGTTAGAACGATCAATGTATGGGTTGAGGTAACTAACGCCCGGGCGGCTGATACGCATGTTATAATTCAAGCCTAAATTGACACCACCAGAGATATTATAGGTGAAGCTGGCAGAGGGAACAAGACTTCCATAATTCTTCTTGAAGTCGGAACCAGAACCAACGATAAAGTGCACCTTCTCCCACGTGTGCTCATAACGTAAACCTGCCTTTGCTCCAAATTTACCCATAGTTGCACTGTACTCAGCATACTCAGCCAAGATACTCTGTGTGTTCTTGTAGTTCACACTGTTAGCAGCATTATAGACTTCAGTGCCTCCTGTGATGTCATAGAACTTAGAATCAGACGAGTTGCGATGAGAGATAAACTTCAAACCAGTACTCAATGTCTGCCCTTTTCCTAATGGAGTCGTAAAGTCAACCTGCACAGTATGCTCCGTTCCACGTGTCTTTGCTGTTGAATAAAGGTCGGATAAAGGAATCGTCACACCTGCTGGCAAAGCATCATAAATACGTCGGTTATTGTTCTCCGCAGGGGAAGTTGTGAAGAGATAACTTAGTGTTAGGCTGCTTGTACGTTCTTTATTGAAAAAGCGTTGATAGTCTACACTTCCATTAAATGACTTGTTTTTATTCTCCATCGTCATCTCGTTGCCATACGTAAAGCCAGTACCATAGGCTCCACCAGAGAAGGTTGTCGTAGGGTGACCATCGTTCTTCATCGCGTAACCAGTCAAACCGAACGTAGCACCAATATTACTCACCGAATCGAGTTCATAGCCTAAGCTGATGTTAGCCATCGTAAAATTGATTTTTGTATTGCCCTTTTGCCAATAGGACATAGCAGACCCATCAGACGAAGTACGGCGCATTTCGGTTTCTGTTCCGTTTGACTTGAATTTCGCTCCCATGACATTGGCACTGTAGGTGAGCTTTCCCTGCTGTCCACTAAAGAAGGTTGTGGTGCGAGAACCATTGTTGCCTAAGGTAAGAGCTACACTGCCATTATATCCGTTCATCTTTGCCTTACTCTTTCCATCACCAGTGTTCATAATGATATTCAGCACACCACCGACACCCTCTGCATCATATTTTGCACCAGGGTTTGTGACTACTTCGATAGATTTCACAGCCGAAGCAGGCATTGCTTTGAATATCTGTGAGGGATTAGAAGAGAACATTACGTTAGGTTTTCCGTCCACATAGACCTTGAAGGAACCTTGTCCATTGACAGTAATATTATCCTGTCCATCCACTGTTACCATCGGAACCTTACGCAACATATCAAGTACGGTGTTTGTCTTGACATCGTTATCACTCTGAACATCGTAGGTCATCTTGTCGGTTTCCATCTTTACCAGCGGCTTTTGTGCCACAACCTCGACATCTTTCAACTGCTTTGTATCGTCTTGTACAAGGAGATTTCCAAGGTTGATAGTACCACCTGTTGCCGTAAGTTGTACCTTACGCAGAATTTCCTTACGTCCCATTGAAGTAAAAGAAACGAGATAACTGCCCTGTCCTGTTACCTTTTGAGAGAACTTTCCGTCCTTTTCTGTCACCGACATAGCCACTGGTGTTTCGCTTTTCTTACCTTTGTAGACTCTGATAGTGGCGTATGGTTCGCCCTCATGGGTCAAAGAATCGAGTAATACACCCGATATAGTTGAGGTCTGACCATGTGCGGTTATGGCAATAGCCATCATACCCAAAGTAACGATTAATCTATTAATTTTCATATTCTCTATGTTTTTACGGCTGAAAAGATGATATAGATGTAATATATAAGGTTGTTTCCCATTACGACAAACAATATCAATAAAATCATTATCAATCACCTAAGCAGTAGTGTTTTACTATCTAATCTATGTGCGCATTATACAATGCAAAACTAACAAAAATAATCTGATAGCACAAGTTTAAAAGTAAAAAAACAACTTAAAATAGGATTCTTTCTTATTATTTCTATGATATACAATAACTATACTAACAACGTATTACATCGTGTTTAACCCTCCGCACCATTGGTGCTAACCCTCCGCACCACTCGTGCTAACCCTCCGCACATTATGTGCGGGATATCAACACGAAGATTGAAAAGCATTAAGAAGAATCATTATTGGCGTGGTAAGAGATATAATAAGCCGTTAATGACCAACTTCGTAAAGATAGACATTTGCCCAATAGTACAAAAAGAAGATGATTACCAAGCCCCGATAATCTTGTCATCAAGGCTTGATAATCATCTTGGAAAGTATTTTCTTACTTCAAACAAACCAACTGGATAGCAAAGCCACCACTCTTAGCCAAGTGCAAGTTGAGTACAGTTTCGTTGTTAACCACCTGCTGTTCGATCGTCATAGAGTAAGGATTCTTATCGTATTCAGCATCAGGACCATCCTTATAGATGATAGCCTTGTAGCTTGTTCCGGGTGAAAGGAAGTCGAGTTTCAACTTGATATCACGTGCATTCTCGTCACTCATACCTCCAACAAACCAGTTCTCACTGTCGCGATCCTTACGTACAGTAACAATATACTTCCCTATCTCCGCCATTGGAATCACAGTCTTTTGCCAGTTAGAAGGCATCGCCTCGATGAAAGCGAAGGCTGGTTGGTCCTTGTAGTTTTCGATTTCGTCGGCTGCCATCTGCCATGGCGTGTAAATAACAACATACTCAGCCAACTGCTTAGCAAGTGTTGTGTGTGGGTGCGTATTAGGGAAAACCTTACCTTCAAGATTAAAGATACCTGGTGTGAAGTCTATCGGTCCAGCTAATTGACGAGTGAAAGGAATTACACAAAGATGGTAAGGAGGATTGCCACCATTGCCGTCCCAAGCATTCCACTCTTGTCCTCTTACACCCTCACTGGCGATAAGGTTTGGATAAGTACGCTGTAAACCGGTTGGCATAGCAGGCTCATGATTAACCACCATAATGTGGTGGCGGGCTGCAGCCTCTATCACCTTGCGATAGTGACGCACACCATATTGAGAGTGCTGGTGCTCCTTATCGTCCATTAGATTATTGACATAACCCGTCTTAACAGCCTTAATGCCCATCTTCTCATAAAGAGAGAAGGCTTCTTCTAACTGGTTCTCATAGTTCTTTGCAGCACCACCTGTCTCGTTGTGAGCGATGAGTGAGACACCCTTTGACAGTGCATACTTCTGCAATCCCTCAAAGTCATAATCAGGATAAGCCTTTGTGAAGTTGAATTTATCACCTTCCTTACCCCAGTCGTTTTCCCATCCATAGTTCCAACCTTCAACCAATACGCCCTTGAAACCATGCTGTGCAGCAAAGTCAATGTAGCGTTTTGTATTCTCGGTTGTGGCACCATGCTTAGGACCGGGAGCCCACGTTGCTGTCTGCATGTGGTAAGACCACCATACACCGACGTACTTTCCTGTTGTAATCCATGATGTATCCTTAATCTTACAAGGGTCGTTGAGGTTCAACATGACACGGTTTGTAATCAAACCGCCCACCTTATTCTCCACTGACAACATACGCCAAGGACTGACGAAAGGAGCTTTTGCACGTACCAAGTCGCCATTTGACCATGGAACCAACTCAGCCTTCAATCTTACATTCCCCTCTTTTGTCTCTACAGGCTTAACGTTCAGCGAAGAATAATCTGTCAGATTCGCCTCATGAAGCATCATATAAAGGTCTGGTTTCGCCTCGATAGTAACCGGAGTGCATACCTTTCCCTTCTTACTCAAGTTGTCCTTTGTCCACAGTCCCTCATAGTAACCAGCATCATAAGGCAATGTCCAAGCCTCTGGATCGCCCTTAAAGTAGAATTCTGTAGTCTCATCCATGATGACAAAGTCCTTCAACTGCTTTTGCTCTGGGAATACATAACGGAAGCCCATACCATCGTCAAAGATACGGAAGACGATATTCAGCTGTCGCTGCTGTCCTTTCTTCTGTACCAACTTCATAGTCAACTCGTTATAATGGTTGCGCACATCGACTTCTTCTCCCCATGGTTGGCGCCACGTTTCGTCCTTTGTAGCTCTTGCAAAAGCCACAACACGGAAGTCACTATCAAGACTTCCATCTTTCAGTTTCATTCCCAAAGCTGAAGGGAGAAGGATTACTTCGCCACCACGACGCAAAGAATAATAAGGTCGTCCAGCATTATCAACACCCACTGTCAGCGTCAGATTGCCCGAAGGTGAACTTACCGTAGCTTCCTGCTTTGCCATCATTGCCATTGGAAGGAGTGCAAAGCACAGCACTAAAAAGAGATTTTTAAAACGTTCTGTTTTCATTTATTGAGATTTTAATAATATTAATTCTTACCATTAACAGCATCAAGTAAGGCTTTCGCCTCACCTGTCTTCAATTGTACAAGGGCGTTATATGCCTCCTTTACCTTCGCATTATTAGGTTGTGCAACACGTGCTTGATACCAGCGATAGATAAGTTCTAAGTCGGCTTGCTGATAGCTTACGCCGGTGAACTTCTGCAACATGAGGAGGTATTTATACCCATACTCCAAGGTTGGTTCGATAGTAGTTCCCTCGCCATAGTCGTTCCATGTGCTTATTTGCAGATACTTCAGACCTGCCTGTCGGGCTGCATCAAGCTGTCGCTGGAACAACGCTCCGTTCTCAGCATTGTAGGTTTGATAACCTGTACCGCCCTCACCTTCTTTGTAATAGTCCCAGAAACCAGGCATAGCACCACCTACAAAGCACTTATAACCCTTAGCTATAGCATAGTTAGGATTAGGATTCACCCATGTATAAACACCTTGTGCATTGTCTGAATAAGTAGCATTATTGACACTACCCATCTTTCCTTCCAGTACAAGGAACATTGGTTTTGTAGTGAGGATAGAGAAACTACGATACCAGTCTTTTGGCGATTCCATCTGAATAGGACCGAAGTCTAATAACAATGGACGACCCTCAACTTTCACATAACTATCATCTTTAAAGAAGTTCTCAGCTAAATAACGTAAGTCCTGACGTACTGTTCCAACCTTATCTGTCACTCCTTCGAGTGTTCTGTCTTCATAAACGACACTCATCTTGAGCCCTGCACGTTTCAAAGCACGGAAGAGTGCTTCAGTATTCGACTTATGTAAGGCGATAGAATTATCACTATTAACGCCATACCAGTCGACCATTACACCGTCTAAGCCGGCATATTTCATCAGCAAACACTGATAATCCAACACAGCCTCATCGCCACTTGCATAAGGACCCGTCTGTGGATAATAGTGTGAAGCTATCTGTCTTTTGCCATTAGCATCGGTCTTGTTAGGGTCACAGTTCTTCATTGTCCAGTGGTAACCCCACTTTCCTTCGTTCTTAGGGTTGGATGTGGTCGTCTCAAACCAAGGCATATAATGTGCATACACCTGCATAGTGTTTGACTTCGTAACGGCAACAGGCACGACTTGCGTAGTCTGCTGACTGCCTTCAGGCTTCTTAGGTGCACCCTCATAGCTGTCTGCACAAGACGCAAAAAGCAATCCTGAGACAGCTGCAATTGTAAATACTAATTTCAACTTCATCTTGTTTAATGTTCTCTTAGCTGACTTTCCTATTCCCAAAGCTGGTGCAGAAAGATTCCTACTTCTTATATTGATACCGCTATCCTACTTTCTGCTGCTATGCAAAAGCTATCCTTTCGTAAGTACAAAGATAAACTTTAAATACCATAAAGAAGAACTTCAACCACATAAAGAGGCATCTTTCTCGAATTATTTTCATGAAGAAAAAGAATTATTTTCATGATAATAAATATTTCTTTTCACGATGAAAAATGTTTTTTTTCATGAAAGTAATTTGCCACAGACAGCTTTTCTATAGGAGAAAGTCATGTTATTAACTTGATATTACATGGGTTGTTGCATCATAAAAGGGGCTGTTTTCTTAGAAGTAAGTAGGTCCTTTCATTCTGTTTAAAACCTATCGAATAAAGCCTTTAAAACCCAATGGCAACTGCATGGACCTAAAATTCCTGCCGTACCATTGGGCATCTTTATAACACTAAACCCATCAAAAATTAACTTTCGTAGCCAGGATTCTGCTTTAAGTTAGGGTTCTTGCTCAACTCCTCTTGTGGAATTGGATAGATACCTGTATGCTTGTCGGCAGGATCGGCTGGCTTCTCCCACCACGCTTTGAAGTAAGTTCCAAAGCGGATGTTGGTTGTACGGCGCAAATTCTCAAATACAAACTCGTGCTTCCACTCTGTGTCAAGATCGTCGAGGGTGAGCGTTGTGAGGTCGTCAAGGCCTGCACGCTTGCGAATCTGATTGATATAAGTGAGTGCTGTTGAGGTGTAACCCAAACGGAAGTTACACTCTGCTTGCATCATTAAAATCTCTGCATAGCGCATTAGTACCCAGTCGTTGTCGCGCTCCCAAGAGTCATTAGCACTCCATTCGTACTTGTTCAGACGTGCACCAGCATTCTTAGCGGCATCAGTAAAGTTATCTATCTCCTCCGTATAGTTCAATGGTGAGCCATCATCCATCAGTACTTCAGAACCATCCTTAGCACTATATTGCTGACCGATGAGCAGACTTTGGCGACGTACATCCTTCGCATCGAATGATGAGTAGAGTCCAGGCTGTGCGCAGATACCGTTACCACACCACTGATAAACGCCAGCTGGATCGAAAGCCAACTTCTGATTATAGTGGTAGGTCATACTTGCAAGATAGTTACCTACGGTTCCCTGCTTGTGATCGTAAGGTATTGCAAAGATGATTTCAGGAGATTTCTCATTCTGAATAGCGAAACTTGCCTTATAATTTGCAGTCAGCGAATAGCCTTGAACCTTATTACAAGCATCAAGACAGTCCTGCCAACGAGCCGTACCAGTAAACACCTCGGCATTGAGATAGAGTCGTGCCAAGAGCGTATTGGCTACGTTCTGGGTAAAACGACCGTAGGTAATGCCAGAAGGCAAGAGTGGGATAATCTCCTTAAGTTCCTTCTCAATGAAGGCAAAGACATCCTTACGCGGAGTATTTGTTGGGAGTTCCTTCTGCGTGAAGTCGGTCACAACAGGTACGTTTCCAAAGCAGTCGAGCAGGTTGTAATAGTAGTAAGCACGCAAGCCACGCAACTCTGCCTCCACTTTCTGCTTATCCTCTGTGGTCAGTCCACTCTGTTCTACCTGATAGATGATGGCATTCACCTTTGAAACACCTGTGAAGTTATATCGCCAAACAGAGAGGATACCAGAGTTCTTAGCGTCCCAGTTGTGGCGTTGGAACTGCTGATAGCGACCACCATCATACCAGTCTGTACCACGGGTTGGGATACATGCTTCATCACTTGAGCACTCCTGTGTGAAGAAGACATACTCACAAGTAGGATAACAGATGATACCTGCACCCTCAGGAGTACCTGAACCATAGCCTCGGAGAGTAGCGTAAGCACCTCCAACGATAGTTGCTACCTCAGAAGAAGTCTTGCCATAGTCATCCTGCGACACCTTATCGTAAAGTTGTTCGTTAAGGTCAGTACAGGAAGCCATTGCTAAGAGCAGTCCTACTCCTAACCAAGTCTTCCGTCCAGGAAGGATATTTGATATGCTAATATTCAATCGTTTCATAATAATTATGTTCTTATAATGTTGAATGTTACGGTAAGATTAGAAGCCAATGTTCACACCCAATGAGAAAGTGCGTGGTCGTGGATAACTGTTGAAGAAGTCAATACCAGGTGAGTTCAGTACGTTATCTGGTACACTTACTTCTGGATCGATACCCTTATAGCCTGTAATACAGAAGAGGTTTTCGCCTGTCACATAGAAACGTAGACGACTAAGACCCATCTTCTTCACTGCATTCATCGGAACAGAATAACCCAAAGTGATAGACTGTAGACGGAAGAAATCACCATTCTCTATGAAGTAATCAGAGAAAGTTGGATTATCAGTAATACCGCTCTTCATGAAGTCGTCGAGGGTGTTCTGTGATGGGAAGCGTGTTGGATCATACATCACCATGCGGCTAACATTCAGTACCTTCTGTCCGAACATACCATAAGCAGCTACGCTTGCATCGAAGTCACGCCATGTTGCATTGAGTGAAAGACCAAGGTTCCACTTAGGCATTGCTGAGCCTAAATAGCCTTCTTTCACCTTTCCATTCTCGTCTTTCTCAAGCATATACTTGCCGTCGTCTGAGATTCCTGTGCAATGAGGACCCCAGAAGGCACCTGCTGGAAAGCCCTCTTTGATGACCTGTGCGTAGGTGTTTGACATACCACGAACACTGTGCAATGGACCTGCTTGAAGTCCTACTGCCTGATATTGGTCGTTAGAAAGCTTCGTAATCTCCTGGTGGTTGTAGGCAAGAGAGAGGTTAGCATCAAGTGTCCAATCCTTCGTACGGACTGCTTTATAACCCAAAGTAAGCTCAAATCCCTTGTTTACTAAGTCACCAACATTCGCCAACATCGTACCCACAAGGTATGGAGGTTGTGGCACTGGATAAGTCCAAAGGAGGTCGGAAGTCTTCTTATAGTAAAGTTCTAACGTACCATTCAATCTATTGTATAGAGAGAAATCAACACCAAGGTTCCACTGTGCTGTTGACTCCCATTTGAGGTCAGGGTTAGGGTTTTGAATCTGTGTGTAGGAGTTCTTCCATGTTCCCGTAGTCCCATCGTAGTAGGCAGAACCTGCTGCAGAGAGGATAGAAAGCGACTTATATTCGCCAATACCATTCTGATTACCAGTCACACCGAAGCCTGCACGAAGCTTTAAGTTGTCGAGCCACTCACGTGTTGAAGCCATGAAAGGTTCTTCAGAGATACGCCAAGCCAAAGAAAGAGAAGGGAATACGCCCCACTTATGGTGCTGACCGAAGCGAGAAGAACCATCATTACGCAGCGTAGCAGTAAGCATATAGCAGTCCATCAGGCTGTAGTTCACACGACCAAAGAACGAAATGAGTTTTGATTCACCCTTATAAGAACCCACATCTCCCTGTCTGTGGTCTGTTCCTGCACCTAAGTTGTTATATCCGAAAGCATCAGAATCAAAGCCAGAGCGTGTTGAGCTGAAGCCTTCATAGGTGTTATCGAGGTAAGAATAACCACCCATAAGATTCAAATGGTGGATGTCTGCGAACTTTTTATCGTATGTTAAGTAAAGTTCTAACTGCTTATTTGTATAGTCATCATAGATTCTTTGACCCCATCCATGCTCACTCTGTCCCTCCATTCGAGCGTAAGTAGGCTTGTATAAGCCCGACTTAACAGAGTTGAATTCATAGGATGTATTGACCGTAGCAACCAATCCTTCGAGGAGAGAAAGCTCTGCCTTCAAGTAGCCTAAGAAGCGATGACGTTTGTGATCTTCAGTTCTGTTATTGTTTAACTCAACTGGATTCTCAGTGTTAGTACCATTGAATTGAGCATAACTGCCGTCTTGATTATAGACAGGGAAGGTTGGTTGAAGGTTAGTCATGCGTTCAAAGATACGGTTATCGACTGGATGCCAACTGTCAAAGTTGGTATTGATGCCCTCATCCAAGCGTAAACGACCATTCATTCCAGTCTGATAAGCAGAGAGAGAACCAGCAAGTCGGTTCATAGTATTGTTCTTAATGACACCTTCATTATTGTTATAAGTGAAGCTGGCACGGTATCCATGCTTCTTCTTTGACGATGAGAAGTTGATATTATGCCCATGAGAGATAGCCGTACGCATAAGTTCTTTCTGCCAGTCGGTGCTTGCTCCGAAGTCTAAAGCACTCATATTACCTGTTGAACGAACATAACTACGCCACTGATTTGCCGATAGTAAGTCGAGTGTTTTGGCTGCAGAAGCTAAGGCAACATAGCCATTATACTGAACAGTATTCACCTCAGTGTCTGAACCTTGACGATTGGTAGTGATGATGATAACACCATTTGCACCACGAGAACCATAGATAGCCGCAGCAGAGGCGTCCTTAAGAATATCCATGCTGACAATCTCTGAAGGTTGAACAGAGTTGATATCAACACCTGGAATACCATCTACAACAACCAACGGACCATTACTTGCCGACAAAGACGTACCACCACGAAGACGGATAGAAGCACCAGACTCAACAGCTCCAGAGCTTTGTACGATAGAAAGACCAGCCACCTTACCCTGCAACAACTGCTCAGTAGAGGTGATAACACCCTGTTTCATATCCTTAGAATTGACTGAGGCAATGGCACCCGTAAGGTCGCTCTTGCGCATCTTACCGTATCCGACGCCCACGATAGTCACCTCATCAAGTGTCTTGGCATCCTCTTCCATCACGATTTTCAAGCCTTTTCCTGCCTGCACATTACGACTTGTATAGCCTACATAGGTGATTTCTAGCATATCACCTTGTCGGCACTGGATAGTGAAATTACCATCAATATCAGTGATAGCACCCACCTTACCGCCTACAACACTCACCGAAGCGCCAATAAGTGGCTCATGACCGCTATCAGATACCGTACCAGTAGCAGTGAAGTCCTGTGCTGATACCTGACTACAGAACATCATCAACGCAAAGAGGATGAGTCTCGATAGTTTATTTTTTATTGTTAGTTTCATAGATTTTAATGCTTTTATGGATTGAATAAGACGAGGAATCATTCTCTCCTCTTCCGTTATTAATCAGCCACAACGAGCGGTATTGTTGATGTAACAACCGTCTTATCGTGCTGATCCTTTACTGTTACCTTCAGTTCAGAAGCTTCCACACCCTGCAACTCCTTGTTCAAGTCGAGTGTTGCCTCACGCTTATCGCGCACGCCAGGCATAGTACCAGTAATCGTCTTTGTACCTGCCACGATAGTATATTTCAAGTCACCAGCCGTACGCTCATTGTATTCACGCGTCAACGTAAGGATGTCCTTACTGCTTAGACGTGTTGGGAAATAAGAGAAAACAGGGTCTGGATAAGGAGTAGCCGTACCAGCCTTCTGCTTTTGATCACCACTATTCACACCCCACTGGTTAGCTCCTGCAGCATCCTTAATGACCTTTATGATAAGATAAGTCATATTTTCAAGCTGAAAAGCTGCCTTTTCATCGGGATCAGCAAGGATGGTTGGCTTGTCTGCCTGCCCTGCATCTTGTGGGTTATAAGCATAGTATTCACTTGGAACACCTACATTCCAAACGTACAAACCATTAGAAAGTTTCTTCAAACCAGTCTTTGCCAACACTGCAGGACGCCATACATCCAAGGTCTGTTGTACGGTCCAATCGTTCAAACCTGAGTGTGCAGCAAACTCTACGAAGTCGGCATCTTTTGCCAATTCTGTCAATGTCTTCTCACCTAACTTATAGACATCAGGATTGAAAACTACCGTCAAAGGCTCGTCTAAGGTGAACTTATCGGTGAAACCCTTATCTTTCTTGCCACTGAAGAAACGGATTCCATCACCTGATTTCTTAAACTCCTTGAACTCAGAACGGCTGTCAGGAGCTGCGAAAACACCCGACCATATACTACCATCTTTCGTCTTCAGACGCTGCCAAAAGCCTGGCCATGCATCATCTTCAAACTTTGAAACATCGCTGTTAAAGTACTGTGTTGGTACCATTGTCTTCTTATAGATGTTGTTACCAACGTATTCCAACTTCGCAAAGTCAGACGAATTGCCACCATGACCAGCATCTGGCTCAGTTGGCTGCCATGCCCATAGATAGAGGTCAACACCCTCCTGAAAACCGACATCAGTCAAATCATAATAGAAAGTAACCTCTTCATCAGCCGTGAAGACAGCAGGAACTGTCCAGCACTTTGGTGCCTTCGGTAGTTCTACACCATCAGCAAACAATGCCAAGGGGAACAAGCACATCAATGCAAATAATATCTTCTTCATATTGATTCTGTTATTTTAGGGGAGTTAGGAAGTAATAAAGTAAGATGGTAACTTATAGGAAAGTCCTACAAAAAGAAGACTTTGAAACTTTGATAAGCCCAAGAGAATAAGTACTGAAACTTCCACGCTCCGAAATTACTTAACCGCCTGTGTCAAATTGTAAGTGTAAGAAACAAAAGGCTGGCCGTTTGTCTTGCGTGTCAAACGATATTCCAGTGTCTTCGTATTACCCGGCACAGCCGTTACAGTGAGTGCAGTCTCAGCCTTTCCGTCATTGAGAAGGAGCCGACTTGGCGTGTTATCACTCTTTGTGAAATTGTAATCCATCTTCCATGTGCCACTTGTAGGCAACAAGAGTGGTGCACTACCTTCTACCGTGAAGGTTGATGGATTACCAGCCTCATCTTGGTTTAGATTGATGACAAACGTGTCAAAATCGAGTAGGTCTGTCAATGTCTTTGTACGAGCATTCGCCTCATCAGTCTGCACAACAGAATTAACAACCCACTTACCGCCAATCTTTTCACTTAGCGTTATCGGTGCTGTAAAACTTCCGTCATCAACTGTAGAACATCCCGTGAACGCCATTGCCGTAGAAAAGAGTAGTCCAATAGCGAACAAATTACCTCTGATTGTTCTCATAGTGAATCTTGTTTTTAGTTATTGAAAATTTATTTTTGTTGATTATTTCTTTATTGGCAAAGTTAGTTACTAAAGTTTCCCACCCCTCTATTTCATGGGTATTTCAACCAAACTGCTTTGCGAATACCCATGAACGTGAGCCGTTAACACTTGTCTAAAATATGTTTACGGTTGTGAGCTTTTCTTGTTGCCTGTCTTCCAATGCTTGGACCATAATCTCAAAGTTGTTCCGCATTGCTGAGTCGGTGACTATTAACTGCCCTATCTCACTAACAGAGAACCCAAGAACGTCACAAAGAGCAGCAAGCAATCTCTCTATGCAATTCAGCACACGATGCCATAACGTAAGTGCCATGACATCATCTTCCATGTCAGCAAACAATTCACCCATGGTCTCATACTCTGACATCCGTTTTTCTAACGACATCACGATATATGTAATGTAGCAGAGCGTTGCATCAGCAATCTGACCATCAAAGTCTCTCCCCATGTATGAGCCGAGTCCGAGATGTCCTTTTGTCTCCTTGTTGACCACTTCAATGTTCCATCGTATCTGGTATAACTCGAAGGCACGCACAAAGCTCATCGATAGATCCGTACTAAGCATGATGTTCCAAGTCTGTCGACGCCCATATTTAATCAGGTATATCCTGACTGGTATATTCCCCAGACAGCCCCTCAACTCAATGTACTGACACTTGTACTTCCGGCAGCATTTGGTACGTCTTGCATACATTGCTACGAGCTCAGCAGCATTGTGTCGCTTATTCTCCACAAAGTACTTTGTCTTTCCCATCTTTGCAAGACCAATGTAGTGTATAGCTCCGTTGCCTACTCTCCTGATTTCCTCAATGAACTTCTCACAGGCAAACCAACTATCCGCCAAGGCATAATGGGGATGAATACCTCTCTTCCACATGCGCTGGAGCATCCTTATGGCGGAGTCCATCTTGCTCATACCGCATTCTTGATTCCGCTCATACGCTGGGCTCTCTTTCATGCGTCTCTTGGAGAATCTGCTGCGGAGTGCCTTCTTGCCAAGTCCGCCGTCCCCTTTCTTTCCTAATTCCTCATGGATGGAGAAGTCGAACGGCAGAGAGGACTTACCATCGAAGAACAGGCACAAAAGAAGCTTGTAGCCTAAGACATAGTTCATTCGTACATGGTCGAAAACCTTGGTAATATGCTCAAACTTCCTACCAGTCTTTTCCAAGGTTGTATCGTCAAATATAACACAGGAGTTCTCGCTCTCTGTCTGAATGCCATTCTTACGGAGAATGCATTCAAAACGAAGAACAGTATAGCTAAGCAAACGACGCCAATTCATTGCCTGCCTGACCATCATACGATAATAGCAGTTCTTTCCAGTGGTGAGAAGATGGTAGAAATTCTTCTTGTATATGGAGTGTATCGTCTCACCATTAATACGGAAAAGACAAAGGGAAAGAATCTGTTGAACAGCAGAGATACCATCGTGTTTCTCCAAAGAAAGCCTACAGAGCAGACGTCCAAAACCAAATTTTGAGAAAAGTGAGAGAATATCGCTACTCATCTTACTTTTAACACTTAAAAGCTTGGATATCTCGCTTAAATTGTCTAATTTTGCATCCAT

Protein sequences of DBSCAN-SWA_4

>NZ_CP054011|1556805:1618228|1567293_1568127_-|WP_004359011.1|DBSCAN-SWA
MSRLTSFLHSRCTIQTNATSWRTSVALGVGIFLFLYLLQPFGISQYRGNTFLMCLGFGVMTIFVQWLCAFLFFKRPLRKNVPITNGYIILYSIAIELAIAISMTLYAAFFFQMPLTWRLFSIFFYWTFLVWVIVTAIFTLVNYNRMLNSRLEEMIKKTTDEQEDILITLHDQNLRGTDLTLPINNLLYIEARKNNVCVCYLKEGKIQKTELRSTLTALKDDLPYDNIFQCHRSFLVNINNISSAKGNSNGYQLRLSGCDDFIPVSRTFVPGLRHFVG
>NZ_CP054011|1556805:1618228|1595636_1596452_-|WP_004358989.1|DBSCAN-SWA
MFKRSFLLSIILILAVVNTQAQERQYTRLKGYYRVYQSTNSMLSYFIDGMMEFYIPLSDTAIEASEGKKGSPFVERKFLGERRRKAPKANGDDTFVRISLPNLERQTLLKSIDSEEYSTRNNGDVYRWADKCGKISKEKRKINGKIEVVTTLEMDELVGQPKHEIDMSQLRMYGIVARMTQYDESESYLSNNLLLASQKHQTFFAHYRGEDDDERIDVWSEFYVSDRMTITESELKRIKKEKNSVWTFSIPAVVPPLDKEVAEAWTKMVEY
>NZ_CP054011|1556805:1618228|1600779_1601748_+|WP_004358985.1|DBSCAN-SWA
MKQFIIDLFKLEKKPVKGLMAYEWVVMAYLVLTLIVIFFMYTTINNPQAMIFGRLRIVALTAAMWVVYRLAPCRATHFLRVGVQLGLLAWWYPDTFEINRHLPNLDHLFAQWEQDLFGCQPALLFSKALPGHLFSELFDMGYAAYYPMIAATAVYYFGWYYKEFNRATFIILSSFFIYYIVFIFVPVTGPTFYYKAIGLQNVTAGIFPNVHDYFNHHQECLPSPGYTDGIFYHLVEDAKAAGERPTAAFPSSHVGVSTICMLLLWHDRNYKLLAILAPFYLLLCCATVYIQAHYLIDAIAGFITAVILFAILLRISRKMITA
>NZ_CP054011|1556805:1618228|1610155_1611718_-|WP_004358980.1|DBSCAN-SWA
MKRLNISISNILPGRKTWLGVGLLLAMASCTDLNEQLYDKVSQDDYGKTSSEVATIVGGAYATLRGYGSGTPEGAGIICYPTCEYVFFTQECSSDEACIPTRGTDWYDGGRYQQFQRHNWDAKNSGILSVWRYNFTGVSKVNAIIYQVEQSGLTTEDKQKVEAELRGLRAYYYYNLLDCFGNVPVVTDFTQKELPTNTPRKDVFAFIEKELKEIIPLLPSGITYGRFTQNVANTLLARLYLNAEVFTGTARWQDCLDACNKVQGYSLTANYKASFAIQNEKSPEIIFAIPYDHKQGTVGNYLASMTYHYNQKLAFDPAGVYQWCGNGICAQPGLYSSFDAKDVRRQSLLIGQQYSAKDGSEVLMDDGSPLNYTEEIDNFTDAAKNAGARLNKYEWSANDSWERDNDWVLMRYAEILMMQAECNFRLGYTSTALTYINQIRKRAGLDDLTTLTLDDLDTEWKHEFVFENLRRTTNIRFGTYFKAWWEKPADPADKHTGIYPIPQEELSKNPNLKQNPGYES
>NZ_CP054011|1556805:1618228|1578293_1579064_-|WP_004359002.1|DBSCAN-SWA
MIPKVIHYCWLSNDPYPDKIQKCMDTWKKVLPDYEIKLWNTENFDMSKAPTYVREAFEQRKWAFAADYIRMYALYTEGGIYLDSDVKVLKSFDEFLNYNFFTSLEYHPKQIEMTGAMDMIDDEGNRIKDGFVSGIQIQAAVMGSEAGCQFVKDVLDDYEKREFIYPEGPRLVCKGVISPFVYARVMEKYGFKYLDKDQPLEDNMMVFRSEIFAGNKYEATPASYAIHYCAHSWKRTPVEKFNRWLKRNIPCLFPKK
>NZ_CP054011|1556805:1618228|1588587_1589916_-|WP_004358995.1|tRNA|DBSCAN-SWA
MKKLYIETYGCQMNVADSEVVASVMKMAGYDVCENEDEADAIFLNTCSVRENAENKIYNRLEALHAEQKKGRDLILGVLGCMAERVRDDLIQNHHANLVCGPDSYLNLPDMIAQCENGTNALDIELSTTETYRDVIPQRIGGNRVSGFVSIMRGCNNFCHYCIVPFTRGRERSRDVESILKEVKDLHDKGFKEVTLLGQNVNSYGLLPNGKRPENGVSFAELLHKVAQSVPDMRVRFTTSNPEDMTEDIIEAVATEPNLCNHIHFPAQSGSNSVLKVMNRKYTREDYLEKVAAIRRLVPDCGLTTDIFIGYHNESEEDFQQTLSLMREVGFDSAFMFKYSERPGTYAAKHLPDNVSEEEKIRRLNELIRLQTEISAEQNKKDEGKEFDILIERFGKRSREQLMGRTPQNKAVVMPRGNHHIGETVRVRITGSTSATLFGEEV
>NZ_CP054011|1556805:1618228|1560506_1560935_+|WP_004365217.1|DBSCAN-SWA
MKVLILCTGNSCRSQMAHGFLQSFDKNIEVYSGGTVPAKQVNAKAVEVMKEARINIASHVPTHVNTYLDKEWDYVITVCGGANESCPMFTGKVRNRLHIGFDDPSEATGSPEFINSEFHRVRDEIKACFYDFYLNELKPQLK
>NZ_CP054011|1556805:1618228|1581177_1583151_-|WP_036885752.1|DBSCAN-SWA
MYKNLTYLIKHSAVILVILFFVRICFAIAFVPMSIISNNLAVFPHLLFNVFRFDLQVVCYVLLLPTVLTFIFAAIRKSWTECVLSRFRRLYFSIISTLLLAISGIDIGFYDNFNSHINITFFDFFNEGPMGLIQTIWEEYHCVYEAIAFLLILSPVLLLIRRIELSKSSSRHPLHSTSRQRLSRFEITKLSATILLYLTFLVIGLRGSVWRFPLQIEDTFVSNQKLLNDLVPNAIYMLKKAYKEKNNAFKIAKTDDLLHEYKFKSLQEALDLYTDGKVKMANNDTLRALQHALFEEVGDSLKQPQPNIVIIYSESWSNYLFNLQQKNAEMYFGLERHFKEDLLFRNFQSVQNGTVASLENLYVSTPFPRFFASAYRFKTLPTSIALPFKASNYTTTFMSGMDAAWENCAEALPHQQFDAVYDKFFILKDYPHATYNSIGVYDEYLFQALLDKLNKPSKKRQMIAVMTTTNHPPFEFPKDLKLPPLPDSFYGKKCFAEHNRKVLDKYLTGFRYYNKALNDFLNRFKASAAAKNTILVITGDHNVRVILNHDVIDKRYEHSVPLYVYLPPYLRKEAYNKLTNRWGSHDDILATLAPFAFRNTKYFKMGKNLLDTSVSDSTYYSANVDQIEAIPTYQKKAERLTAARNFLRLVYFAKLFR
>NZ_CP054011|1556805:1618228|1584592_1586605_-|WP_004358997.1|DBSCAN-SWA
MKGLLKTTFGSPIALVFNLLLAYAIFFVARLTYFFVNYSYFIDGLSASSLWMWVRGSLLFDTTAILYTHILYIVMMLLPLWRKENQAYHRLCKWVFMVVNALSLAINLADSVYFPFTLRRTTTTVFREFDNENNIAGILFHNAITHWYLFLIFILILWLANKLYVMPRTDYRSYQSLRQRLVYAAQLFICFAVAAVLTVAGCRGGLQSGVRPITISNANQYVERPTDCALVLNTPFALIRTIGKSDFSVPDYFPSLAAAREVYDPVYWMQYKEPNPASGVRLPNKKNIVILIVESFGREYIGAFNRDFFDGKYKGYTPNVDKLIDKSLVYRFSYCNGRKSIDGMPSILCSIPRFGEPFILTPASMNNYTGMPGLLSKWGYQTAFFHGANRGSMGFLAFANKIGFQHYYGRQDYDEDPRFGGDKDFDGNWGIWDEPFLQYYCAKMGEMKQPFMTALFTVSSHDPFVVPEKYKNIYKEEHLPIQKCIRYTDMAIGKFFESASKQPWFKNTIFVLTSDHTNQSDHEQYKTDIGGFCSPIIIYDPSGEIKPGRVDGVAQQIDIMPTLLFHIGYNATPYLAFGKDLLHTPAKETWAVNYLNGIYQYIKYGYVLQWDGKQTKAIYRVTDALMKHNLLGHVPEQTKMERELKAIIYQYMYRMVHDKMHPTINNPEDQ
>NZ_CP054011|1556805:1618228|1575378_1575795_+|WP_004359005.1|DBSCAN-SWA
MVIRIKELWQRWRKDFWRLFRFGITGTICSLIHYGIYCLFLLFTNTTIAYTAGYGVGLLCNYGLTTYFTFKGKPSKNNVAGFVGSHILNYLLEIGLLHIFLWLGVSKWLSPILVMVIVVPINFVLLRLVFVKGKKEHG
>NZ_CP054011|1556805:1618228|1614753_1615974_-|WP_036885748.1|DBSCAN-SWA
MKKILFALMCLFPLALFADGVELPKAPKCWTVPAVFTADEEVTFYYDLTDVGFQEGVDLYLWAWQPTEPDAGHGGNSSDFAKLEYVGNNIYKKTMVPTQYFNSDVSKFEDDAWPGFWQRLKTKDGSIWSGVFAAPDSRSEFKEFKKSGDGIRFFSGKKDKGFTDKFTLDEPLTVVFNPDVYKLGEKTLTELAKDADFVEFAAHSGLNDWTVQQTLDVWRPAVLAKTGLKKLSNGLYVWNVGVPSEYYAYNPQDAGQADKPTILADPDEKAAFQLENMTYLIIKVIKDAAGANQWGVNSGDQKQKAGTATPYPDPVFSYFPTRLSSKDILTLTREYNERTAGDLKYTIVAGTKTITGTMPGVRDKREATLDLNKELQGVEASELKVTVKDQHDKTVVTSTIPLVVAD
>NZ_CP054011|1556805:1618228|1603385_1605863_-|WP_004358983.1|DBSCAN-SWA
MKINRLIVTLGMMAIAITAHGQTSTISGVLLDSLTHEGEPYATIRVYKGKKSETPVAMSVTEKDGKFSQKVTGQGSYLVSFTSMGRKEILRKVQLTATGGTINLGNLLVQDDTKQLKDVEVVAQKPLVKMETDKMTYDVQSDNDVKTNTVLDMLRKVPMVTVDGQDNITVNGQGSFKVYVDGKPNVMFSSNPSQIFKAMPASAVKSIEVVTNPGAKYDAEGVGGVLNIIMNTGDGKSKAKMNGYNGSVALTLGNNGSRTTTFFSGQQGKLTYSANVMGAKFKSNGTETEMRRTSSDGSAMSYWQKGNTKINFTMANISLGYELDSVSNIGATFGLTGYAMKNDGHPTTTFSGGAYGTGFTYGNEMTMENKNKSFNGSVDYQRFFNKERTSSLTLSYLFTTSPAENNNRRIYDALPAGVTIPLSDLYSTAKTRGTEHTVQVDFTTPLGKGQTLSTGLKFISHRNSSDSKFYDITGGTEVYNAANSVNYKNTQSILAEYAEYSATMGKFGAKAGLRYEHTWEKVHFIVGSGSDFKKNYGSLVPSASFTYNISGGVNLGLNYNMRISRPGVSYLNPYIDRSNPTVLSYGNPDLSVEKSHNVSLVFNYFTPKFMMNMTLGEAFANNQIEQYSFMNGTVLNTTYGNIVRSRWTNFSTFMNYAVTPKTRIMLNGSFDYGDIRSQQLGEYNHGWQASAFLGVQQTFPWKINWSVFMGGLTKKYLLQGHNGGFNMFTSTLSKSFIKDKLNLSFMYFVPLTGKMHIKQYSHGANFENHMNITIPAQHVALTLTWNFGNTKKQFQTHKSNISNDFQEKKNDQQMNGVGMGAGTGM
>NZ_CP054011|1556805:1618228|1563971_1565201_-|WP_004359012.1|integrase|DBSCAN-SWA
MKQEKMKVLLYLKKSGLDKSGKAPIMGRITLGRSIAQFSCKLSCNPDLWNPRESRMDGKSREAVEINGKLENLLLSVQSAYQSLLSKGCLFDAADVKELFQGSVQTRCMLIERLDMLIKEKESHVGIDIKEGAIHGYHSTRIHLQKFIQRKYKVTDLAFSQLTENFIYEFGQYFLGECGFQESTFYNAATHLKTVCRLAYREGLADVLLFDKAKISKGDKRLPKALDKEALDKLKALNFEDLEEEMETARDIFLFACYTGAAYCDLMELDKSHLVRDDEGSLWLKFNRHKTGVPCRVKLLPEAIRLMEKLHSDGRETLLPCIKYKNYQICLKALRLRAGISFPFTTHTARHTFATLITLEQGVPIETVSKMLGHSNISMTERYAKVTPQKLFEEFNRFLSFTEDMQMSI
>NZ_CP054011|1556805:1618228|1571572_1572577_-|WP_036885753.1|DBSCAN-SWA
MSQKKNNKRLLAVLTMALFSIVSFAQGVKLADGVEPLPADAETPGSEYTLVFHDEFNEPDGTLPNTKVWRYCTRRPQVTWARFLSNSPEVAFMKDGNLVLRAIPNSDRSKDDVEMLSGGIETSQSFTFRFGRVECRAMVNPFIGNFPAIWMMPKSKFGWPKGGEIDIFEQIDNEQRCYATVHSAWTQSHGNEPHSGNLWMSMNRYHTYAVEWEEDVLTFFADGKRVFQYKKQNDSQEQWPFDKSNFYLILNQSVGNGSWAKKADVNHTYEMRVDWIRVYQKEKHIPMSISVPMTKIQESTESDDIYSLQGAKIGTHESELPKGIYVLNGKKFVK
>NZ_CP054011|1556805:1618228|1601888_1603022_-|WP_004358984.1|DBSCAN-SWA
MCKKFVYGVAVSDYNFIGREVETNRLMNNFRGGINTILMSPRRLGKTSLVMRVCEKMKSEDIITIYLDIFGCKSEYDFYNRLASEVLKQTASKQSMWLEEAKEFLYRLTPKISFSPEPNSDFAISLGITPKTHTPEEVLEMVEKIAIKKGKQIVVCIDEFQQIGEMTDSKHVQARLRSVWQHQKHVSYCLFGSKHHLMSSIFLHRSMPFYQFGDLIVLGKIPSAEWVEYIVSHFADGKRTISSALAEEICSFTDNYSAYVQQLSWLVYTQKEEGETVDEIDIKQATDDLLATNEVLFMQMVEPLSEYQLNFLRALCSGVTKNFGLAKIREKYQLGSYSNISRLQKALFDRDLIEKRGMELAITDPVFAKWFQRKMMF
>NZ_CP054011|1556805:1618228|1599708_1600698_+|WP_004358986.1|DBSCAN-SWA
MKKILITGASGFIGSFIVEEALRRGMETWAVVRRTSSREYLQDERIHFIELDFSSVDKLKEQLSGHQFDYVVHAAGVTKCLNKEDFFRVNRDGTRNFVEALQALNQPLERFVFLSSLSIFGAIREQQPYKEIEPTDTPQPNTAYGKSKLEAEQLLPSSFPYIILRPTGVYGPREKDYFLMAKSIKGHSDFAVGYKQQDITFVYVKDVVQATFLALDHGKIGSAYFLSDGKVYQSTTFSDLIHEELGRPWWIRITAPIWVLRVVTFFGDLIGHATGKISALNNDKYQILKQRNWRCNIRPAIEELGYKPEYDLKRGVKETIEWYKKEGWL
>NZ_CP054011|1556805:1618228|1608428_1609661_-|WP_036885750.1|DBSCAN-SWA
MKLKLVFTIAAVSGLLFASCADSYEGAPKKPEGSQQTTQVVPVAVTKSNTMQVYAHYMPWFETTTSNPKNEGKWGYHWTMKNCDPNKTDANGKRQIASHYYPQTGPYASGDEAVLDYQCLLMKYAGLDGVMVDWYGVNSDNSIALHKSNTEALFRALKRAGLKMSVVYEDRTLEGVTDKVGTVRQDLRYLAENFFKDDSYVKVEGRPLLLDFGPIQMESPKDWYRSFSILTTKPMFLVLEGKMGSVNNATYSDNAQGVYTWVNPNPNYAIAKGYKCFVGGAMPGFWDYYKEGEGGTGYQTYNAENGALFQRQLDAARQAGLKYLQISTWNDYGEGTTIEPTLEYGYKYLLMLQKFTGVSYQQADLELIYRWYQARVAQPNNAKVKEAYNALVQLKTGEAKALLDAVNGKN
>NZ_CP054011|1556805:1618228|1596479_1597136_-|WP_004358988.1|DBSCAN-SWA
MRRKIFFSHKEELWNSWSHSGGIVLGVVFGTIFLVWCSKERSGWATAGVILYLVGMLFSYITSTVYHALSAHSVWKERLRKWDHAAIYWHIAGSYSPITLIALRNQGAWGWGLFAFVWLCAILGTISSFRKLRDHSNLETLTFIGMGLSVLVAFKPLVDALETQSLVWIFAEGVMYITGALFYSLNKRKYMHTVFHFFVLAGSICHIIAVWGILKEYL
>NZ_CP054011|1556805:1618228|1577106_1578288_-|WP_004359003.1|DBSCAN-SWA
MKDKIKQFINYPLFSNRWFLMGLWFIIALAGMLKYKRSFNNFLIFRGVYWHTVNQTSLYAAYPAEYGDVNHYGPVFSLVIAPFAILPLWAGMLLWLLFLTAWLYLAIIRSGLREQQKIFILWFCGITLPTALFMQQFNIAVAAMILSSFFFIEKEKDGWAAFFIVLGTLVKLYGIVGLAFFLFSRHKLRFLMWLAIWSVVLFCAPMLISSPSYVIGQYHEWFTCLVEKNAENLGSIQQNISLLGLVRRTTGCMNYSDLWLILPGMMLFALPYLRFSQYKNLAFRETILASVLLFVILFSTGSEASGYVIALLGVCIWYTAVPWKRGKWAIALLIFVFLLSGMGSSDIFPKFIREAYIKQYALRALPISILWLWLCYELCTKDYTPIEKADAHE
>NZ_CP054011|1556805:1618228|1594472_1595474_-|WP_004358990.1|DBSCAN-SWA
MKKSIFIFLACLVLVSCGQQRSNISFPEEKFTVDLRLPTTPVKGQGLSSLCWVYGMLATLETEHIIRGDSINLSPDYVARMYLSEQANRRHLLPNKVVQKEADITTRGMCTMALDLIQTYGLQHYDAYRHKPDMDYNVLCRKLDKGNDAEKLLDKYIGPLPKQVFILGALYTPLEFAHSVCTDDEYVALTSFTHHPYGQRFPLEVPDNYFHDTFLNVPLDTMMNRIVQSLRAGHPVCWEGDISEPGFLFGNGFAVLKNEDKKVTAERRQTSFEAHRTTDDHVMEIVGLAHDQHGRRFFLCKNSWGTANRYHGFMFLSENYVRMKTIAVVLRAI
>NZ_CP054011|1556805:1618228|1569604_1571503_-|WP_004359009.1|DBSCAN-SWA
MEEQIEVKELDSVVVHFSGDSGDGMQLAGNIFTTVSATVGNGVSTFPDYPADIRAPQGSLTGVSGFQVHIGAGKVYTPGDLCDVLVAMNAAALKMQYKHCKPNSTIIIDTDSFGQRDLQKAEFRSDDYLGEMGIDPDRVVACPITKMVKDCLADTGMDNKSMLKCRNMFALGLVCWLFSRDLELVNNYLETKFKKKPAIAEANIKVVRAGYDYGHNVHASVPNTYRIESTVKQPGRYMDITGNKATAYGLMAAAERAGLRLFLGSYPITPATDILHELSKHKSMGVTTVQCEDEIAGCASAIGAAFAGALAATSTSGPGICLKSEAMNLALIDELPLVIIDVQRGGPSTGMPTKSEQTDLLQVLYGRNGESPMPVIAATSPTDCFDAAYNACKIALEHMTPVVLLTDAFIANGSSAWKLPNIEDLPEIHPHYVTEDQKYKYTPYKRDPKTLARYWAIPGTEGYTHILGGLEKDGETGAISTDPENHDKMDHLRWNKVARIPVPDLVVQGDEEDADLLIVGFGSTYGHLYSAMKELRRKGNKVALAQFKYVNPLPKNTAEVLSRYMKVVVAEQNLGQLAALLRIRINHFAPYQYNQVKGQPFVVTELVTTFEKLLKAPLPKEETGTFYTKILE
>NZ_CP054011|1556805:1618228|1586627_1588487_-|WP_004358996.1|DBSCAN-SWA
MKEFIQVLRRFIPPYKKYLVLSIIFNILSAFLNIFSFATLIPLLQILFKVDAGTGATRAMSWSEGSFKEVLSNNADYYTQIYITSWGPTTVLLAIGLILAFMTFLKTGAYFLSSASIIPIRTGVVRDIRNQLYEKITSLSLGFFSEGRKGDIIARMSGDVQEVDNSIMSSIDMLFKNPVLIIIYFTTLLVISWQLTLFTLIFVPIFGWFMGFVGRKLKQNSMTAQKLWSDTMSQVEETLGGLRVIKAFCAEGMMNERFDKINSEYRSDIMRVNIRQQLAHPMSEFLGTVMIVVVLWFGGTLVLGESPIISGPTFIYYLVILYSILNPLKEFSRAGYNIPKGLASMDRIDKILQAEVKINDPEKPVHIDSFEHEIEFRHVSFAYTDGKDDEGKPELHWVLKDINLVIPKGKTVALVGQSGSGKSTLLDLIPRYYDVQEGEILIDGINIKDLGVHDLRQLIGNVNQEAILFNDSFKNNISFGVNATDEAIVEAAKIANAHEFIMHSERGYDTNIGDRGGRLSGGQRQRVSIARAILKNPPILILDEATSALDTESERLVQDALYKLMKTRTTIAVAHRLSTIKNSDEICVLHEGEIVERGTHDELMDIEGYYKKLHDMQEI
>NZ_CP054011|1556805:1618228|1579152_1579932_+|WP_004359001.1|DBSCAN-SWA
MEKKEISVVINTYNAEKFLQRVLDSVKGFDEIVICDMESTDHTVEIAQRAGCKVVTFPKGNHTCVEPARNFALQSAKGPWLLVVDADELVTPELRIYLYQHINKPNCAKGLYIPRQNRFMNTPKKGFSKDYQLRFFIREGTFWPPLIHTIPQVQGKVEYIDNHLYNVKLLHLAENYLADMLEKCNRYTTNEVLKKKGKNYGVGALLFRPFWRFFKSYFMNGEIRNGVTGFIDSVMTGFYQFMIVAKIIESKIKKQTEDE
>NZ_CP054011|1556805:1618228|1575989_1577114_-|WP_036885784.1|DBSCAN-SWA
MNKKIIGYDAKRIVRNGTGLGSYGRTLINDLAPLMPDTNLRLYAPDAGRDDLRNQVELRDNVQFCYPDHLRFRLQRDWWRVKGVVKDLKADGVELYHGLSGELPSGLAAAGIPGVVTVHDLIFLRHPEFYPAIDVFFYKRKFYQTLREASRIIAISECTKRDILYYGDFPEDKIDLVYQSCSTRFSQSVSPELIEEARRKYQLPQRYILNVGTVEVRKNILLGIRTMAKLPSDLHLVIVGRQTKYQKKLDAEIKRLGIGNRIHFLQGVPNDLLAAIYNQAEAFIYPSRYEGFGIPIIEAIQSGLPVVAAAGSCLEEAGGPDCLYVGPDDVDGNAAAILSAIEHRKEIVCKSQRYVKRFENQDVASQILEVYNKV
>NZ_CP054011|1556805:1618228|1556805_1558089_-|WP_036885754.1|integrase|DBSCAN-SWA
MKSTFAILFYIDRSKTNEDGLCVIRCRITCNGTSSSFSTQLQTSPDEWLARKGCIKATTGNSSGINLQLNSIEECLHSLYERTLREENYITAEYLKERYMQQSRPMPTLTELYQSVCEYKEELQGRTLSKATVRAFKDSYKSFVHFLQVRDRADCMPTEVDKTLLEDYRLFMLRDLGNKESSVGNRLRHLHQVIRKALQERYVREDPFELIDIETPTYERNALTADDLQKLLAYRPHRSTDNHCRLIFLLGCFTGLAFSDLKKLRMDDVYTFGDGRRYISLCRTKTQNRSIVPLLPVAEKILAIVSHGRREGLFFREFPSNSNFNRTIQEICIKAGLLPHTQATSHTARHTFATTICLENGLPIETVSKMLGHRFISTTEIYARVTKSKIAKEMQPLMGSEHTRVLRKALRLCPSRTPKKSSPIIGM
>NZ_CP054011|1556805:1618228|1558101_1559355_-|WP_004359018.1|integrase|DBSCAN-SWA
MEKEKFKLLFYLKRGTQDKNGKSPIMGRISAGRSMVQFSCKCSCTPRLWDSRKNRLLGKSAEAVSVNKELDRLQVSIHKVYESLSGKSDAPITAERVRELVFGLNSESQGLLHHTDEYIDRFRERVGIDRSERRLKCLLLFHKHLANFVRYRYRVEDIPVQKADIAFIKDLEDYFAKEKGFKLNTSAGYLSMLASLLKDLHKRHIIDTYPFINHSIRWEVGTPRYITREEVGLIAALGEDKLQGYEKVSRDMFLFSCLTGLSYTDVYHLTEQHVFHEAGMTWIRKPRIKTGNVCHIPLLPEATAIIERYRGIHTRAFRHEPPKGYLLPIPGCDTVNIHLKKIARLCGIQKTLTYHMARHTFASQMTLSEGVSIESVSKMLGHSQIKTTQVYAETSPERVFLDIEKILPQLAHYQLTN
>NZ_CP054011|1556805:1618228|1606386_1608408_-|WP_004358982.1|DBSCAN-SWA
MKTERFKNLFLVLCFALLPMAMMAKQEATVSSPSGNLTLTVGVDNAGRPYYSLRRGGEVILLPSALGMKLKDGSLDSDFRVVAFARATKDETWRQPWGEEVDVRNHYNELTMKLVQKKGQQRQLNIVFRIFDDGMGFRYVFPEQKQLKDFVIMDETTEFYFKGDPEAWTLPYDAGYYEGLWTKDNLSKKGKVCTPVTIEAKPDLYMMLHEANLTDYSSLNVKPVETKEGNVRLKAELVPWSNGDLVRAKAPFVSPWRMLSVENKVGGLITNRVMLNLNDPCKIKDTSWITTGKYVGVWWSYHMQTATWAPGPKHGATTENTKRYIDFAAQHGFKGVLVEGWNYGWENDWGKEGDKFNFTKAYPDYDFEGLQKYALSKGVSLIAHNETGGAAKNYENQLEEAFSLYEKMGIKAVKTGYVNNLMDDKEHQHSQYGVRHYRKVIEAAARHHIMVVNHEPAMPTGLQRTYPNLIASEGVRGQEWNAWDGNGGNPPYHLCVIPFTRQLAGPIDFTPGIFNLEGKVFPNTHPHTTLAKQLAEYVVIYTPWQMAADEIENYKDQPAFAFIEAMPSNWQKTVIPMAEIGKYIVTVRKDRDSENWFVGGMSDENARDIKLKLDFLSPGTSYKAIIYKDGPDAEYDKNPYSMTIEQQVVNNETVLNLHLAKSGGFAIQLVCLK
>NZ_CP054011|1556805:1618228|1562647_1563943_-|WP_004359013.1|integrase|DBSCAN-SWA
MRSTFKILFYINRQKTKADGNTAILCRITIDGKNTAITTGEECQPAEWNSKQGLTTNRKTNQRINEFRELVEKTYRDILTRDGVVSVELIKNSLQGIATNPTTLLAMSKAELQAVKESVGKSRAEGTYLNLYYSDKNLRDFIENKGVQDISIVTITESLFEEYRFFLKKRGLKASTVNTNLCWLSRLMFRAVSSRIIRCNSFENAKYEKEEKKIRFLQKGDVMKLMAMTMNDRESELARLMFVFSCFTGMAIADMENLEYRHIQTAADGRKYIRKERQKTKVEFVVPLHPIAEAIIRHCLEEQKGNEEQQTVKEKGKKHIFPRECSRSVIDGRLSIVGKACGIRQRLSYHVARHTFGTMSLSAGIPIESIAKMMGHASISSTQIYAQVTDNKISEDMDRLIAKQSAKDKETMEREACEPSEVSIYKMEETA
>NZ_CP054011|1556805:1618228|1616109_1616616_-|WP_004358977.1|DBSCAN-SWA
MRTIRGNLFAIGLLFSTAMAFTGCSTVDDGSFTAPITLSEKIGGKWVVNSVVQTDEANARTKTLTDLLDFDTFVINLNQDEAGNPSTFTVEGSAPLLLPTSGTWKMDYNFTKSDNTPSRLLLNDGKAETALTVTAVPGNTKTLEYRLTRKTNGQPFVSYTYNLTQAVK
>NZ_CP054011|1556805:1618228|1560947_1562000_+|WP_004359015.1|DBSCAN-SWA
MEKKQGIGFFEKYLTVWVALCIIIGIAVGQWLPAIPQTLSKFEYANVSIPVAILIWLMIYPMMLKVDFQSVKNVGKRPKGIIVTGVTNWLIKPFTMFGIAYLFFYVVFKAFIPAGLAEEYLAGAVLLGAAPCTAMVFVWSYLTKGDAAYTLVQVAVNDLIILVAFAPIVAFLLGVGGVSIPWDTLLLSVGLFIVIPLAAGVITRIMVIRRKGVEYFNNIFIKKFNNYMVGGLLLTLIILFSFQGETILNNPLHILLIAVPLVLQTVLIFFVAYGWSKWWKLPHDVAAPAGMIGASNFFELAVAVAISLFGLQSGAALATVVGVLVEVPVMLMLVRIANNTRHNFTETYHS
>NZ_CP054011|1556805:1618228|1568203_1569214_-|WP_004359010.1|DBSCAN-SWA
MNQYTAQDFKKGQPRWCPGCGDHFFLASLQKAMAELGVPPYETAVISGIGCSSRLPYYANTYAMQTIHGRAAAISTGAKVTNPNLTIWQVSGDGDALAIGGNHFIHAMRRNVDLNMILLNNRIYGLTKGQYSPTSPRGFVSKSSPYGTTEDPFRPAELCFGARGNFFARSVASDNTETIEILKAAYLHKGAAVCEILQNCVIFNDGCHNSVYTSQGRKENAIYVKHGEPLIFGPNQEFGLVQEGFGLKVVKIGENGITRDDILVHDAHSQDNTLQLKLAMMSNEDGFPVALGVIRDVEAPTYDAAVNQQIEEVKAQKHYHTFMEMLETNDIWEVKE
>NZ_CP054011|1556805:1618228|1591819_1592236_+|WP_004358993.1|DBSCAN-SWA
MTINEAQDAVISEFEDFTDWMDKYQMLIDLGNELEPLEEQYKNEQNLIDGCQSRVWLQCDNVDGKLIFTADSDALITKGIIALLIRVLSNHTPQEIIDADLYFIDKIGLRQHLSPTRSNGLLSMVTKIKAYAVGFSLQ
>NZ_CP054011|1556805:1618228|1597144_1599442_-|WP_036885751.1|DBSCAN-SWA
MRKEKKSSKRLTKKQLAEKLMSFFQTQPDETFSFKQIFHALKLTTHPAKMLAIDVMEELAWDDFLSKVGESAYTLNTKGQVQEGTFIRKANGKNTFLPEDGGTPVFVSERNSMAALNGDQVRVQFMARRQNHIKEAMVIAILQRKKDTFVGRLRVEKDIAFLVTQENLFIHDILIPKKKLKGGKTDDRALVKITKWPDADHKNLVGEVVDVLGEAGDNDVEMNTILAQYGLPYKYPKRVEDAAEKISAEITAQDYAEREDFRDVWTCTIDPRDAKDFDDALSIRKLESGLWEVGVHIADVSHYVKEGDIIDREAQQRATSVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSCIFNLDDEANVKAYRIVHTVIKSNRRYAYEEAQQILEDNGVIDGTGEPAPNPGKAGYKGENAEQIITLDRLAKLIRGRRMKAGSVKFDSEELHFDIDEKGKPIRCYFKRSKDANKLIEEFMLLANKTVAESVGIVKKGKKAKTLPYRVHDNPDPQKFENLREFTAKFGYKLKSASTKGATARALNKLMDEVQGKREEKVIQTIALRSMMKAKYTTHNIGHFGLAFDYYTHFTSPIRRYPDTMVHRLITRYQNGGRSANKDHYEELCEHCSDMELVAQNAERDSIKYKMVEFMSEHIGECYDAHISGIQSFGIYAEIDENHCEGMIPMRDLDDDYYDFDEKNYCLVGRRRHHVYQLGDPIRIQVAKADLERRQLDFALDDGRPLKAKQTAAEYAVNRKNDRKSSKRGSKSRRRK
>NZ_CP054011|1556805:1618228|1574422_1575367_+|WP_004359006.1|DBSCAN-SWA
MIKLATVSPCYNEEEVLEQSAAQLMELFDELISQGKISDDSMIVFVNDGSRDRTWEIIQQLHSQHPRIKGINLAHNVGHQNAIMAGMMTAKDWADAVITLDADLQDDYQKCIPQMVDAFEEGNEIVYGVKVSRKADPILKRMSAQAFYHLQEKMGVNSIFNHADFRLMSRQSLEILSGYKERNLYLRGLIPSIGLKSTTVDDRISERKAGTSKYTLRKMLSLALDGITSFSVKPIYYVIYLGIAFLFVTLCIGIYVIHAFVNHTEVAGWASLILSIWLVGAMLMISIGAVGVYIAKIYEEVKQRPLYNISQILD
>NZ_CP054011|1556805:1618228|1565392_1566850_-|WP_172891275.1|transposase|DBSCAN-SWA
MDAKLDNLSEISKLLSVKSKMSSDILSLFSKFGFGRLLCRLSLEKHDGISAVQQILSLCLFRINGETIHSIYKKNFYHLLTTGKNCYYRMMVRQAMNWRRLLSYTVLRFECILRKNGIQTESENSCVIFDDTTLEKTGRKFEHITKVFDHVRMNYVLGYKLLLCLFFDGKSSLPFDFSIHEELGKKGDGGLGKKALRSRFSKRRMKESPAYERNQECGMSKMDSAIRMLQRMWKRGIHPHYALADSWFACEKFIEEIRRVGNGAIHYIGLAKMGKTKYFVENKRHNAAELVAMYARRTKCCRKYKCQYIELRGCLGNIPVRIYLIKYGRRQTWNIMLSTDLSMSFVRAFELYQIRWNIEVVNKETKGHLGLGSYMGRDFDGQIADATLCYITYIVMSLEKRMSEYETMGELFADMEDDVMALTLWHRVLNCIERLLAALCDVLGFSVSEIGQLIVTDSAMRNNFEIMVQALEDRQQEKLTTVNIF
>NZ_CP054011|1556805:1618228|1580125_1581127_-|WP_004359000.1|DBSCAN-SWA
MISIITPVFQSERYLEKLINSILNQTYCDWELLLIDDGSTDGSAEICDRYAHKDNRIRVFHKANGGVASARNQAMDMATGEYLAFADSDDWVEPCWLERLYKTAKEQEADIVVSDYYEEYPQKTIMRSKDDDDVIVLNRKDALFLTFQDKITSYLWSMLIRRDIAQERFAPYRAFEDYATLFAWMFQANRVVLLHTPLYHYRQYAYSCLHSNMKQNITDYIEATITRYKLVKESSFLQDNISQFNAAYIYSLVKGLKDIVRSPYDNDFKQKLLKKVSDEIRTIELPSPYKMLGFKYYVRYTLLCKSLKLFKHIVGGTAVFSFNRSRKKVELFS
>NZ_CP054011|1556805:1618228|1592515_1593091_+|WP_004358992.1|DBSCAN-SWA
MRKLRTIEMNRLSLEEFKEADKLPLIVVLDDVRSLHNVGSVFRSADAFRVEAVYLCGITATPPNAEIHKTALGGEDSVDWRYFERTEDAIEELHHQGVFVYSVEQVEGSTKLQELNTENPTNHQHPTPNTQHPVIHYAIVLGNEVKGVKQSVVDMSDGCLEIPQFGTKHSLNVSVTTGIVIWEFARQLLIK
>NZ_CP054011|1556805:1618228|1562234_1562651_-|WP_004359014.1|DBSCAN-SWA
MKANDNLKAVTNTACHRSIFDWGSNMQVVRKGNGDITMTEGELAKFFGVTWSKLNHRLQALMRFSNLHPDERSAGEDDIYVNEQLKGYAPLYPLPIIIALSFQLDSTEAHLFRKYLCERLQKPASVITPIFLLGSTDN
>NZ_CP054011|1556805:1618228|1590460_1591705_+|WP_036861976.1|DBSCAN-SWA
MNKNTNDFEIMAPVGSRESLAAAINAGANSVYFGIGKLNMRSHSANHFTIDDLKEIAETCNAKGIQTYLTVNTVIYGEDIETMHEIIDAAKAANITAVIASDVAVMMYCRQVGVEVHLSTQLNISNIDALKFYAQFADVAVLARELNMDQVKEIHEQIIKQNICGPKGQPIRIEMFCHGAFCMAISGKCYMSLHDSNRSANRGACTQICRRSYTVTDNETGNQLEIDNKYIMSPKDLKSVRFIDKMMDAGVRVFKIEGRARGPEYVHTVVSCYKEAIESVLDGTFTEEKKDQWDERLSTVFNRGFWDGYYQGQKMGEWTKDYGNKATEKKVLIGKVIKYFSRLGVAEVAVEANTFVKGEKLLITGNSTGAMFLNAEEIRYDLNPVDKAEQGWRVSIPVPDKVRPNDKLFKLVTK
>NZ_CP054011|1556805:1618228|1611757_1614694_-|WP_036885749.1|DBSCAN-SWA
MKLTIKNKLSRLILFALMMFCSQVSAQDFTATGTVSDSGHEPLIGASVSVVGGKVGAITDIDGNFTIQCRQGDMLEITYVGYTSRNVQAGKGLKIVMEEDAKTLDEVTIVGVGYGKMRKSDLTGAIASVNSKDMKQGVITSTEQLLQGKVAGLSIVQSSGAVESGASIRLRGGTSLSASNGPLVVVDGIPGVDINSVQPSEIVSMDILKDASAAAIYGSRGANGVIIITTNRQGSDTEVNTVQYNGYVALASAAKTLDLLSANQWRSYVRSTGNMSALDFGASTDWQKELMRTAISHGHNINFSSSKKKHGYRASFTYNNNEGVIKNNTMNRLAGSLSAYQTGMNGRLRLDEGINTNFDSWHPVDNRIFERMTNLQPTFPVYNQDGSYAQFNGTNTENPVELNNNRTEDHKRHRFLGYLKAELSLLEGLVATVNTSYEFNSVKSGLYKPTYARMEGQSEHGWGQRIYDDYTNKQLELYLTYDKKFADIHHLNLMGGYSYLDNTYEGFSSTRSGFDSDAFGYNNLGAGTDHRQGDVGSYKGESKLISFFGRVNYSLMDCYMLTATLRNDGSSRFGQHHKWGVFPSLSLAWRISEEPFMASTREWLDNLKLRAGFGVTGNQNGIGEYKSLSILSAAGSAYYDGTTGTWKNSYTQIQNPNPDLKWESTAQWNLGVDFSLYNRLNGTLELYYKKTSDLLWTYPVPQPPYLVGTMLANVGDLVNKGFELTLGYKAVRTKDWTLDANLSLAYNHQEITKLSNDQYQAVGLQAGPLHSVRGMSNTYAQVIKEGFPAGAFWGPHCTGISDDGKYMLEKDENGKVKEGYLGSAMPKWNLGLSLNATWRDFDASVAAYGMFGQKVLNVSRMVMYDPTRFPSQNTLDDFMKSGITDNPTFSDYFIENGDFFRLQSITLGYSVPMNAVKKMGLSRLRFYVTGENLFCITGYKGIDPEVSVPDNVLNSPGIDFFNSYPRPRTFSLGVNIGF
>NZ_CP054011|1556805:1618228|1583639_1584596_-|WP_004358998.1|DBSCAN-SWA
MKRALNKTLYIIAYGFWYLVALLPFPVLYLLSDGLYLLMSRVVKYRHKVIWTNLKNSFPEKTDDELRQIEQGFYRWFCDYIAETLKLMTMSKMQLMKRMTFTGTEELNRVLSEGKSAAVYLGHLGNWEWITSLPYWVNNTLCCQLYHPLENEYFDRLFKFVRERQGALCIPMQESLRKIIQFGRNGKPLVVGYISDQAPFWWSIHHWVQFMNQETPVLTGGERIVKHMSQVFVYGDVTRTRRGHYNCEFRIIREETKGLPDYEITDLYFKELEQSIRHQPEIYLWSHNRWKRTRARFDEYFEEIDGKVRLREGKEMIY
>NZ_CP054011|1556805:1618228|1616770_1618228_-|WP_172891275.1|transposase|DBSCAN-SWA
MDAKLDNLSEISKLLSVKSKMSSDILSLFSKFGFGRLLCRLSLEKHDGISAVQQILSLCLFRINGETIHSIYKKNFYHLLTTGKNCYYRMMVRQAMNWRRLLSYTVLRFECILRKNGIQTESENSCVIFDDTTLEKTGRKFEHITKVFDHVRMNYVLGYKLLLCLFFDGKSSLPFDFSIHEELGKKGDGGLGKKALRSRFSKRRMKESPAYERNQECGMSKMDSAIRMLQRMWKRGIHPHYALADSWFACEKFIEEIRRVGNGAIHYIGLAKMGKTKYFVENKRHNAAELVAMYARRTKCCRKYKCQYIELRGCLGNIPVRIYLIKYGRRQTWNIMLSTDLSMSFVRAFELYQIRWNIEVVNKETKGHLGLGSYMGRDFDGQIADATLCYITYIVMSLEKRMSEYETMGELFADMEDDVMALTLWHRVLNCIERLLAALCDVLGFSVSEIGQLIVTDSAMRNNFEIMVQALEDRQQEKLTTVNIF
>NZ_CP054011|1556805:1618228|1573563_1574343_+|WP_004359007.1|DBSCAN-SWA
MILLSFDTEEFDVPREHGVDFSLEEGMKVSIEGTNRILDILKANNVCATFFCTGNFAELAPEVMERIKNEGHEVACHGVDHWQPKPEDVFRSKEIIERITGVKVAGYRQPRMFPVSDEDIEKAGYLYNSSLNPAFIPGRYMHLTTPRTWFMQGKVMQIPASVSPHLRIPLFWLSMHNFPEWFYLRLVRQVLRHDGYFVTYFHPWEFYDLKSHPEFKMPFIIKNHSGHELEQRLDRFIKAMKADKQEFITYVDFVNRQKK
>NZ_CP054011|1556805:1618228|1593537_1594368_+|WP_004358991.1|DBSCAN-SWA
MKKVLLYLLALPVIMLLLASCHSEEDDFIDKPDPKSLIIKGVAKTPDGQPIPNIELKLDYTIMSALYSIKVYHKAKATTDKDGNYIMFFNLNDKELKSLTTYSPEEGFVYHLQMTLDLSKLDDKVYLLPTDITAVRPLSERKLFYDAYGMPGRLQQGQVYEQNILIPRKQLAKVRIETNGAINEKDSFAICNKVRYGIESQIPNGFNGERGYLMFYQPIKLKNTHSQTVQISCAAEEDSKLSLYRLPDGEFNYKEYSSEVEVPVMQAGGELILRTH

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_036885754.1|1556805_1558089_-|integrase	site-specific integrase	H7BUI8	unidentified_phage	3.8e-18	28.2
WP_004359018.1|1558101_1559355_-|integrase	site-specific integrase	H7BUI8	unidentified_phage	1.8e-28	29.8
WP_004365217.1|1560506_1560935_+	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	8.2e-18	42.0
WP_004359015.1|1560947_1562000_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_004359014.1|1562234_1562651_-	hypothetical protein	NA	NA	NA	NA
WP_004359013.1|1562647_1563943_-|integrase	site-specific integrase	H7BUI8	unidentified_phage	5.0e-18	29.5
1563089:1563103	attL	NA	NA	NA	NA
WP_004359012.1|1563971_1565201_-|integrase	site-specific integrase	H7BUI8	unidentified_phage	2.5e-27	34.7
WP_172891275.1|1565392_1566850_-|transposase	transposase	NA	NA	NA	NA
WP_004359011.1|1567293_1568127_-	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_004359010.1|1568203_1569214_-	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_004359009.1|1569604_1571503_-	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_036885753.1|1571572_1572577_-	glycoside hydrolase family 16 protein	NA	NA	NA	NA
WP_004359007.1|1573563_1574343_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_004359006.1|1574422_1575367_+	glycosyltransferase family 2 protein	S5FKN0	Shigella_phage	7.5e-40	36.5
WP_004359005.1|1575378_1575795_+	GtrA family protein	NA	NA	NA	NA
WP_036885784.1|1575989_1577114_-	glycosyltransferase family 4 protein	A0A125SJ91	Acidianus_tailed_spindle_virus	1.0e-06	26.0
WP_004359003.1|1577106_1578288_-	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_004359002.1|1578293_1579064_-	polysaccharide biosynthesis protein	A0A2K9L2U7	Tupanvirus	1.9e-09	37.3
WP_004359001.1|1579152_1579932_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004359000.1|1580125_1581127_-	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	1.4e-12	39.6
WP_036885752.1|1581177_1583151_-	LTA synthase family protein	NA	NA	NA	NA
WP_004358998.1|1583639_1584596_-	lysophospholipid acyltransferase family protein	NA	NA	NA	NA
WP_004358997.1|1584592_1586605_-	alkaline phosphatase family protein	NA	NA	NA	NA
WP_004358996.1|1586627_1588487_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.3e-50	30.1
WP_004358995.1|1588587_1589916_-|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_036861976.1|1590460_1591705_+	U32 family peptidase	NA	NA	NA	NA
WP_004358993.1|1591819_1592236_+	SufE family protein	NA	NA	NA	NA
WP_004358992.1|1592515_1593091_+	RNA methyltransferase	NA	NA	NA	NA
WP_004358991.1|1593537_1594368_+	hypothetical protein	NA	NA	NA	NA
WP_004358990.1|1594472_1595474_-	cysteine peptidase	NA	NA	NA	NA
WP_004358989.1|1595636_1596452_-	hypothetical protein	NA	NA	NA	NA
WP_004358988.1|1596479_1597136_-	hemolysin III family protein	NA	NA	NA	NA
WP_036885751.1|1597144_1599442_-	ribonuclease R	Q0GXV6	Lactococcus_phage	6.9e-63	32.0
WP_004358986.1|1599708_1600698_+	NAD(P)-dependent oxidoreductase	A0A2R8FEJ0	Brazilian_cedratvirus	3.1e-12	23.7
WP_004358985.1|1600779_1601748_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_004358984.1|1601888_1603022_-	ATP-binding protein	NA	NA	NA	NA
WP_004358983.1|1603385_1605863_-	TonB-dependent receptor	NA	NA	NA	NA
1603635:1603649	attR	NA	NA	NA	NA
WP_004358982.1|1606386_1608408_-	glycoside hydrolase family 97 protein	NA	NA	NA	NA
WP_036885750.1|1608428_1609661_-	hypothetical protein	NA	NA	NA	NA
WP_004358980.1|1610155_1611718_-	RagB/SusD family nutrient uptake outer membrane protein	NA	NA	NA	NA
WP_036885749.1|1611757_1614694_-	TonB-dependent receptor	NA	NA	NA	NA
WP_036885748.1|1614753_1615974_-	hypothetical protein	NA	NA	NA	NA
WP_004358977.1|1616109_1616616_-	DUF5004 domain-containing protein	NA	NA	NA	NA
WP_172891275.1|1616770_1618228_-|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NZ_CP054011.1|WP_004360068.1|948908_949325_+|PcfK-like-family-protein	948908_949325_+	138 aa aa	40	NA	NA	No	NA

Protein sequences of NZ_CP054011.1|WP_004360068.1|948908_949325_+|PcfK-like-family-protein

>NZ_CP054011.1|WP_004360068.1|948908_949325_+|PcfK-like-family-protein
MKGTEHFTRTIAEYLNGRAATDPLFALNLMKPNKSIEECVTYILNQVQASGCNGFEDDEIYSMAVHYYDEDEIKVGKAITCRVAVNHIVELTEEEKAEARQEAIKQYQREELAKIQSRNARPQKKETAEVVQPSLFDF

gnl|BL_ORD_ID|40 information

• hit_Aca_id: gnl|BL_ORD_ID|40
• identity: 0.6083916083916084
• query_coverage: 1
• hit_coverage: 1.0