CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP054018	Rothia dentocariosa strain FDAARGOS_752 chromosome, complete genome	3 crisprs	csa3,DinG,DEDDh,WYL,c2c9_V-U4	1	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP054018_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP054018_1

596027-596099

Orphan

Consensus_repeat	Method
GTTCAGGAAGCAGCACCTGCAGCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP054018_1

>merge|NZ_CP054018|1|596027-596099|CRISPRCasFinder
GTTCAGGAAGCAGCACCTGCAGCTCCCGCACCTACGACTCAGGCTCCTGCTCAGGAAGCTCCCGCAGCACCTG

>NZ_CP054018|1|1|596027-596099|CRISPRCasFinder
GTTCAGGAAGCAGCACCTGCAGCTC	CCGCACCTACGACTCAGGCTCCT
GCTCAGGAAGCTCCCGCAGCACCTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054018.1\|WP_037231887.1\|584804_585851_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|377369
NZ_CP054018.1\|WP_037231994.1\|582208_584620_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|377369
NZ_CP054018.1\|WP_004006183.1\|586016_586400_-\|acyl-CoA-carboxylase-subunit-epsilon	unknown	unknown	gnl\|CDD\|379386
NZ_CP054018.1\|WP_004006194.1\|598443_599949_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NZ_CP054018.1\|WP_004006185.1\|588354_588639_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|183800
NZ_CP054018.1\|WP_071193288.1\|588785_589784_+\|biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|223417
NZ_CP054018.1\|WP_004006184.1\|586495_588094_-\|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|227136
NZ_CP054018.1\|WP_037231891.1\|600154_601828_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP054018.1\|WP_004006196.1\|602068_604270_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224684
NZ_CP054018.1\|WP_004006193.1\|596848_598444_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl\|CDD\|234572
NZ_CP054018.1\|WP_004006198.1\|604939_605530_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP054018.1\|WP_004006187.1\|589786_590278_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|367615
NZ_CP054018.1\|WP_004006197.1\|604415_604829_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319947
NZ_CP054018.1\|WP_004006188.1\|590443_591613_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NZ_CP054018.1\|WP_004006200.1\|606104_606425_-\|ligand-binding-protein-SH3	unknown	unknown	gnl\|CDD\|224987
NZ_CP054018.1\|WP_004006199.1\|605678_606074_-\|multidrug-efflux-SMR-transporter	unknown	unknown	gnl\|CDD\|224987
NZ_CP054018.1\|WP_004006190.1\|592575_594798_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_CP054018.1\|WP_004006201.1\|606458_606950_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NZ_CP054018.1\|WP_004006189.1\|591597_592518_+\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|223704
NZ_CP054018.1\|WP_004006192.1\|596542_596839_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810

Protein	Function_ID	Function_description	E-value
NZ_CP054018.1\|WP_037231887.1\|584804_585851_-\|restriction-endonuclease	gnl\|CDD\|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	1.61553e-23
NZ_CP054018.1\|WP_037231994.1\|582208_584620_-\|restriction-endonuclease	gnl\|CDD\|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	3.73265e-09
NZ_CP054018.1\|WP_004006183.1\|586016_586400_-\|acyl-CoA-carboxylase-subunit-epsilon	gnl\|CDD\|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	2.56723e-14
NZ_CP054018.1\|WP_004006194.1\|598443_599949_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_CP054018.1\|WP_004006185.1\|588354_588639_-\|hypothetical-protein	gnl\|CDD\|183800	PRK12863, PRK12863, YciI-like protein; Reviewed.	1.54071e-15
NZ_CP054018.1\|WP_071193288.1\|588785_589784_+\|biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	2.09437e-52
NZ_CP054018.1\|WP_004006184.1\|586495_588094_-\|acyl-CoA-carboxylase-subunit-beta	gnl\|CDD\|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP054018.1\|WP_037231891.1\|600154_601828_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.24213e-76
NZ_CP054018.1\|WP_004006196.1\|602068_604270_-\|S9-family-peptidase	gnl\|CDD\|224684	COG1770, PtrB, Protease II [Amino acid transport and metabolism].	0
NZ_CP054018.1\|WP_004006193.1\|596848_598444_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_CP054018.1\|WP_004006198.1\|604939_605530_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.87019e-12
NZ_CP054018.1\|WP_004006187.1\|589786_590278_+\|PH-domain-containing-protein	gnl\|CDD\|367615	pfam03703, bPH_2, Bacterial PH domain. Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.	4.37756e-06
NZ_CP054018.1\|WP_004006197.1\|604415_604829_-\|VOC-family-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	7.10683e-28
NZ_CP054018.1\|WP_004006188.1\|590443_591613_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.33291e-26
NZ_CP054018.1\|WP_004006200.1\|606104_606425_-\|ligand-binding-protein-SH3	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	4.70751e-17
NZ_CP054018.1\|WP_004006199.1\|605678_606074_-\|multidrug-efflux-SMR-transporter	gnl\|CDD\|224987	COG2076, EmrE, Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism].	3.46605e-27
NZ_CP054018.1\|WP_004006190.1\|592575_594798_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_CP054018.1\|WP_004006201.1\|606458_606950_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	6.65195e-19
NZ_CP054018.1\|WP_004006189.1\|591597_592518_+\|serine/threonine-protein-phosphatase	gnl\|CDD\|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.63937e-56
NZ_CP054018.1\|WP_004006192.1\|596542_596839_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	8.49435e-33

>NZ_CP054018.1|WP_004006190.1|592575_594798_+|NAD-dependent-DNA-ligase-LigA
MTENLAETPASLDRALKALDSSAELTDTIRAEYAELTDTIRAARHDYYQADAPTLSDAEYDRLYRRLEQIEAQYPALIANDSPTQEVGGEVSEAFSPVTHLVRMYSLEDVFSLEELRAWLTKAEENTRLLTGTAPQWLTELKIDGLAVNLLYRNGVLVRAATRGDGTTGEDVTHNVRTIASIPQKLAGENHPAELEVRGEVFISSADFKKLNEKMVSEGKNPFANPRNAAAGSLRQKDSAVTAERPLSMYVHGVGSRTGLDVNSQYQTYEQLAAWGLPTSPYSKLFTSVDDILRYIAEYGEKRHSLVHEIDGIVIKVNDFVAQTQLGYTSRVPRWAVAYKYPPEEVNTKLLDIRVDVGRTGRVTPYGVMEPVLVSGSTVERATLHNQDVVKAKGVLIGDTVVLRKAGDVIPEIVGPVVALRNGHEREFVMPTECPSCGTTLAPGKEGDVDMRCPNYRSCPAQLTERIYYAASRGAFDIEALGFEAAKALTAPAEPEQPPLTSEAFLFDLTAEDLRDVKIRREKKVKGVGTGKFELVPYFYTKPTKAKPEPVPTKNTQNLFVELEKAKSQPLWRVLVALSLRHVGPTAARALATEFGSMDAIAQADRDRLAAVDGVGGVIADSIIEWFATDWHREVLARWADAGVRMEDERDASIERTLEGVTVVVTGTLVNYSRDSAKEAIIVRGGRASGSVSKKTHFVVAGASAGSKLDKAEALGIPVLDEDGFTKLLAHGPDALTPGE
>NZ_CP054018.1|WP_004006189.1|591597_592518_+|serine/threonine-protein-phosphatase
MATPLNLTLRTGGATHRGAHRDNNEDSMAVAGSLCVVADGMGGHEAGEVASRLCVRQLAYSHFFTRPGGMSEEEQENYRQRVEKIKQDYQDKNSKQRHRRLTNELNHEIVRALDRTREILGETNDSIKDALSRSGGTTVTGAWLTNIGQQYLWVVFNIGDSRTYRLMREDDGIHHAEMERLPGNEGNVSLEQVTTDHSEVQYLVDEGQITQLEALTHPRRNVITRALGTGNFWEPDFWVLPARAGDRLMLCSDGLSGELSHEYMARVLTSIRHPQDAADVLQHEALRSGGRDNITVIVADAIEAQD
>NZ_CP054018.1|WP_004006188.1|590443_591613_+|adenylate/guanylate-cyclase-domain-containing-protein
MTHESLSGDSVEATPYKNPRTLGPETQMLNLRILQNLAQNNIYRDETSKEGVRVLERALLGEGRRYKPREAAAAAQMSLEDARRIWRNMGFPDIHAADPHFTELDVNMLEDLENLNRTNLVAEESIVSLTRSVGQLTDRIVAWQIETLVHDIMDRDGVDDAQARRQLLFRLADLMPVLEELALYAYRRQMYTGVLRLALRENKKLGPEPAQLPLVRGVGFVDLVSYTSLVRNLSAPELARLINRFEQSCLDIIAPSGGRIIKTLGDEVFFLTEAPEAIAEISLKLAEQIGKDPELPEVRVAFIWGEVLANRGDVYGSSVNLASRLVSLAEPGSVLTDSETAETLKEYGDRFTLTYQGTRNVRSFGNVDPVAVTPGASYITENDTSWQLP
>NZ_CP054018.1|WP_004006187.1|589786_590278_+|PH-domain-containing-protein
MKLRGKLYPGEQTIILTRAHPGALVGTFVYLLVAFTSASFASTARSSGLLFWAGSVVAAVTALVALRKIWRWSVTRYAITTHRIMIIKGLMRRKADISLLLDGMGNRWVSQSSLGAWMGYGSFHVDYAGGFRHQLMHLPNPERFRNIVEHAWQDYYPLRVSYV
>NZ_CP054018.1|WP_071193288.1|588785_589784_+|biotin--[acetyl-CoA-carboxylase]-ligase
MMVHMSLPDQRPAILDPSRILPEAREAGYSFVRVYDVVDTTNTEIVRRLTRGEPCERTELGELSVFTTLYMTAGKGRMDRAWTAPAGTCLATSIVVRPHAGVGQQLPITSYHWLTMLAGLSVLDVWRELGLDAALKWPNDLVIRGRKACGILALLLSEPAQVPEEKRQMSIVVGIGQNLNMREDQVPVPTATSALIQRGEPVDNHVVLNRMLTIFARRYREFVSVGGDPQKTLLCGQSLLDQARAATVTLGAEVSVHLPDGRIVTGVATDLDAQGRILIRDTTGAVQAYSVGDIEHLRPADGSYGNFYPAHRQEDSPTLTPSEITPNTSAKA
>NZ_CP054018.1|WP_004006185.1|588354_588639_-|hypothetical-protein
MAYYVISYVYGDPALQDAHRPAHREYLSTRVQEGTIVVSGPLLKDSVSVGALLIAQVDSFDAAETIVKNDPMKIGGAVESYTIGEWNPVLGSIR
>NZ_CP054018.1|WP_004006184.1|586495_588094_-|acyl-CoA-carboxylase-subunit-beta
MSENAQEYDLSTTAGKLADFYARREQTLAPGGQAAVDKQHARGKNTARERIDMILDEGSFVEFDALARHRTTAFGMDKKKPLGDGLVSGYGTIDGRLVAIYSQDFTVYGGSLSQVNGEKIVKVQKFALKNGCPVIGINDGGGARIQEGVASLALFADIFRMNVRSSGVIPQISIIMGPCAGGAAYSPALTDFIVMVDKTSHMFITGPDVIKAVTGEQVDMETLGGARQHNAMTGTSAYLAEDEEDAFDFVRELLEFLPSNNLSESLPLDHDQEFEVVVDDLDLDTLIPDSANQPYDMRDVIESVVDDGHFFELQALFAPNVMIGYARVEGRTVGIVANQPTQFAGCLDIAAAEKAARFVRNCDAFNIPILTFVDVPGFLPGTDQEFNGIIRRGAKLLYAYAEATVPLITIITRKAFGGAYIAMGSKTLGADINMAWPTAQVGVLNGQGAVNILYRRDLAAAAEAGEDVEGRRSELIEQYEEEILNPYQAAELGYVDEVIAPHETRVRIISSLRALHDKRAAMPAKKHGNIPL
>NZ_CP054018.1|WP_004006183.1|586016_586400_-|acyl-CoA-carboxylase-subunit-epsilon
MAGYNPLNYFSFGKKKDAPTTPKESADQVLPRDGASEAASHADTVDHADIQDDSQSSEQPLLRVIKGNPTVEEIAALTVLVASYQSSQAQQEHNSILTAASRLLNRRQRLGASLRPGPGSWRRARPM
>NZ_CP054018.1|WP_037231887.1|584804_585851_-|restriction-endonuclease
MSKEYKNYAVPLEAVEILFLPALRRLSRAVPRTVADISQSLSEQTHALGTKEELQDLKSDAFMYQVKATLQAMARLGYVLVVPKTTTSKTRYLLSDSGADILTAQIRRRGSVIPQSARYELQKLFTPLYASAPKGSDTSDFPDTPASEDKHEHSSYTPMATPLSPGASLRDAHPDLILAQATYAADFAGDLIERIYAVSPTYFEYIVADVFNSLGTFHAAVTGGPNDHGIDVLVHYPKELCFPPIYVQAKHYCGSSKVTLSDIQKFAGAVLLHNGLQGVFVTCGEFAAQVPQQMEALPGGNRIALVDRDRLVSLMIRHRVGVIHTPGECTYRIDEEYFSRGIPQDSHE
>NZ_CP054018.1|WP_037231994.1|582208_584620_-|restriction-endonuclease
MLRHEKTPVDNILKALSWDDIPEEYRDDCRDIAVRAALALLRQFERAHEHGQKLLFPELYTPVGVEIGFTMTQRYIAVGKSVLFRDAIDKIIVAFVNHDYLDVSLSNLHPGNLLYSLSERGLDFLQRPEDEQREILEDLFYPIIGTHLFYMQDYYPRLLAQINVRNIAPIALSVIPLHLSVTESKLRELVMRECGFVQGWYGLTQLEQQLFETSCAESVRGLLDAGYLRPKEHHDKIAYALTTEGKNLRYSFPHGVPAQALSDIFDDAPVSLLTVDQLKHHEKLLIRMGHVIMDAVLAKGDNAKLPLADVDRAIAQDAEIQQLADEDSPEYLQGREHVYDVLLAHRYLEEGDEDEQEVFMVGSAYADALSSVEDGSIDELMRRAFLDPAAAEQIPHPHHMLFDILTLVRDNPDINFYDLFTKVEDTLDLPYLQARLAPHRSNTTPRVRNRYAVAVQVLKQEGYLQVHGGQSGRLSRKDPERYTLTQSAIELLDRFPNGIPETVAARIVPLQKQALRHKLPEDIAAALNTGRKPYEKREHSQDSYSYQNSRGHYGSGPRSGYGAPVQATPQNIAQAQGGSGISSAAYASAQSFTQPAPAYQAPAPVPSQTPGVEQSSDAPSDALSAVESARNAVQDAQRRYRDVFKRALLQPQLQAVTKDRFTDIAADLFSVRGYTAERADASQGVQVIAYPSGGQRDRAFYVRAQRSADGAVSVQDITNLYLSLEQLGGQLGAFITDGTFGDDAYDEYIRCSTKYPHILVDLIAGDELMNRLIAHRLGIRDGRVPGTIELDDAYFSGSDSAAS
>NZ_CP054018.1|WP_004006192.1|596542_596839_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MSAITTEQVKHLAELARIEMTEDELNAMAAELDIIVSSMEHLSETVTPDIPPTSHPISLQNVLREDVVGQTLTQEEALSGAPDAQDGKFRVPAILDED
>NZ_CP054018.1|WP_004006193.1|596848_598444_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MNELIVLTAAEAAQKLAAGEISAVELTRAHIDRIEATDGTPLSENRADGKSGLNAFLHINREEALETAQAVDADRAAGQELPALAGVPIAVKDLIVTKGQPTTAGSRMLEGWMSPYDGTVTRKVRAARMPILGKTNLDEFAMGSSNEHSAFGVVRNPWALDRAPGGSGGGSASAVAAFQAPLALGTDTGGSIRQPASLTGSVGVKPTYGSVSRYGVIAMASSLDQVGPCARTVLDTAMLHEAIAGHDPLDSTSLNEPVGPFAAQALEGANPESLKGMRIGVIKELGGGSGSGFQQGVLDRFHDALKLLEKAGAEVVEVSLPSVKEAISAYYMIMSSEVSSNLAKYDGVRYGLRVIPEDGPVTIERVMAATREAGFGDETKRRIILGTYALSAGNYDAHYGAALRVRTLIQRDYTAAFEKCDVLVSPTSPTTAFKLGEKTKGDPMAMYLGDVATVPVNLAGVPAISLPAGVADEDGLPVGIQFTAPAREDARLYRVGAGLEALLNDTWGAPFYTRIPNTENLISDFDFGGTK
>NZ_CP054018.1|WP_004006194.1|598443_599949_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MSEEVLSFEEAIEKYDPVLGFEVHVELNTNTKMFDAAPNVFGDEPNTNITPVSLGLPGVLPVVNKVAVESAIKLGLALGCDIAPISYFARKNYFYPDSPKNFQTSQHHGPIAENGNLDVELEDGTVFTVEIERAHMEEDAGKLTHVGGADGRIQGAAFSLVDYNRAGVPLIEIVTRPIVGAGERAPELARAYVAAIREIVKGLGISDARMERGNVRCDANVSLMPKGSEKFGTRSETKNVNSLRSVERAVRYEIRRHAAILERGEKIQQETRHWHEDTRETSSGRPKSDADDYRYFPEPDLVPVVPETAWVEELRASLPEPPAERRRRLKAEWGYSDEEFRDVVNAGALDVVEQTIAAGASASAARKWWMGEIARKAKQAEVELTDLGVEPATVVELEALIGEGKINDKIARKVLEHVLAGEGKPAEIVEARGLAVVSDDGALTAAVEEALAAMPDVADKIRAGKVQAAGAIVGQVMKATRGQADAARVRELILQACGVEG
>NZ_CP054018.1|WP_037231891.1|600154_601828_+|ABC-transporter-ATP-binding-protein
MKVMRSLRPGTLVMLTALTLILSASSVLESVIIKYLTDAVTSYDRILFAWMLAAVPTYLVVDAFLHYVRQYRAALAGVQIQNNLRAELFRRIGLSPVARLTGRSSEYYFSQFTSQLENIKTNYIDVIFWGGYLTAQLIFAIVAAFILNPFMACAVLALSLPVGLMPVLTRKRIGAVTKAYASQTDALNEVSGDTLRSALGWKILGAYSFVAKRFSEELSEWYVAARSYQRTQERVDAVNSMFTKLLYLGTWLAGGALVLSGLSSVGEVVAFAQLTGMICMPLFMSTGLLIQYYAGREIIRKIDAEVPAVEDDRPGEPLTLDAFTYRDVKPLGEKSAGYGVSFIFETGKKYLVIGASGSGKSTLFKPLFGNHPEYSGTIEVHESGQTRDLREIAEQDMHASLGLLAQDSHLLHDSLRENIRLYDPSVPDVQILRACERAGLGEWASAKGLDYMLSDDLRSLSGGEKQRILLARMLLHERSFYIVDELTTGLDHATAGRVERALFESMKGFVYITHRTVPEILAAVDEVLVMEDGELVASGTWDDVHAAALERGLVGHP
>NZ_CP054018.1|WP_004006196.1|602068_604270_-|S9-family-peptidase
MSDASNTTPAEEVPLVPIPKKVEHIREYHGDTFIDHYEWMRDKEDQEVLDYLNAEADYTAAVTADQQPLRESIFEEIKSRTLLTDLTVPNRIGDWWYYSRMVPGGQYPIFYRYPALHEGDEVVRYTPPVIKPGEPLEGESVVLDCNEYAKDMEFFALGVFQPSRNGKLLSISVDEKGDERYEQRFLNLETGEFLPDTIPNISGGSFFINHAQQLVYTVPDDSWRPYRVYVHDIGAGTEDHLIYEETDPTMWLGSAMSADRSSIVLSSGNSEFTEVSLVPIAEPKSPPRVIIPRDARIEYQAEPITIAGETHLLIQHDYKALNSELVLADMPQEGESLEEYSKRWVPVIRHSENVRLEGFTLSATHLVVTARADTTTRLFLAPREQLPVQWRRKKPAGITFMEPAGFDEELYTAGVLRAENYSPVIRIAYTSFLTPRRVYDYFPMSQTLLLRRETPVLGGYQREDYRAYRDWAPAADGTLIPISVIHRADLDLTQPHPVLQYAYGSYEISMDPMFSIPTLSILDRGVVYVIAHIRGGGEMGRTWYLNGKKLHKKNSFTDFVDVTDYLATKPWADPARIACYGGSAGGLLMGAVLNLAPEKYAVSIAQVPFVDALTTILDPDLPLSALEWEEWGNPIEDKEVYEYMKSYTPYENIRPVRYPAIAAVTSLHDTRVFYVEPAKWIAKLRETIDPASPTPLLKIDMTGGHGGGSGRYTRWREIAWDYAFILTHLGITK
>NZ_CP054018.1|WP_004006197.1|604415_604829_-|VOC-family-protein
MKFIDRYPLVVTPVKDSSRDFWTSYFDFQIIFDSSWFTLLASQDGSTSIAFMTPDHPSAPPGSETFNGIGMCLELEVQDATATYNDLKAQGLDITYPLTNEPYGQRRFGFSDPSGLWVDIVEQIEPAAGYWDKYMFP
>NZ_CP054018.1|WP_004006198.1|604939_605530_+|TetR/AcrR-family-transcriptional-regulator
MEGQRAAQREATVSALVTEARQRFARDGYTSVRIDDIVSSLGITKGALYHHFKNKKDLFRAVVCEVQQDVGYQIEDAARSCATPWEELVEGSKTFILASIEPNVRRIMLVDAPAVLGWHEWRALDESSSMVLLADILKTLMEQEIIAKQPVEPLSHLLSGAMNEAALWLAETDSPDALEDTMKTLTRLLESLRISA
>NZ_CP054018.1|WP_004006199.1|605678_606074_-|multidrug-efflux-SMR-transporter
MTSQKSDDSVQAQQKGRAWGALLLAGGFEVGYALSVNGSQGFTNLAWSLIALVFFLCTLFFLSVALKKVDVGIGYAVWAGIGSVGAALLGPVFFDEVLTPAKAFWLVVIIAGVIWLKLTDSPTLRNRNSHG
>NZ_CP054018.1|WP_004006200.1|606104_606425_-|ligand-binding-protein-SH3
MSWIFIAIAVVFEVTVGIAAGKAQGFKNIPWTATTLIAGALGTYFLSLALLSFDVGVGYAIWTSVSGVGIVIVGALFLGQQLTWSKLLGILVVIAGVIGLNLAGSL
>NZ_CP054018.1|WP_004006201.1|606458_606950_-|nucleoside-deaminase
MTKPTTLHTIMVEAVHQCIQHVDSGGLPFVGVVVQSGVAVSNFGFNRVYETGDASAHAEVVAMRDAMSRLKCSDLSGTVLLATGEPCGLCYRFAQNCGVDAIYVAADREEAASWGFDYHSSYALFGITDDMRAQFYRALPVPDRYEPFARYLEISGGHTSDLE

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP054018_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP054018_2

1624601-1624684

Orphan

Consensus_repeat	Method
CAGGTGTATCGGGAGTGTCAGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP054018_2

>merge|NZ_CP054018|2|1624601-1624684|CRISPRCasFinder
CAGGTGTATCGGGAGTGTCAGGTGTATCGGGAGTGTCAGGGTGATCGCTGTCGTGATCACCAGGTGTATCGGGAGTGTCAGGTG

>NZ_CP054018|2|2|1624601-1624684|CRISPRCasFinder
CAGGTGTATCGGGAGTGTCAGGTG	TATCGGGAGTGTCAGGGTGATCGCTGTCGTGATCAC
CAGGTGTATCGGGAGTGTCAGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054018.1\|WP_004005140.1\|1618496_1618973_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|240046
NZ_CP054018.1\|WP_004005138.1\|1617275_1617695_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054018.1\|WP_004005133.1\|1611004_1611163_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054018.1\|WP_004005136.1\|1614784_1616455_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NZ_CP054018.1\|WP_004005141.1\|1619015_1619393_-\|DUF488-family-protein	unknown	unknown	gnl\|CDD\|225730
NZ_CP054018.1\|WP_168160742.1\|1630889_1631228_+\|LppP/LprE-family-lipoprotein	unknown	unknown	gnl\|CDD\|379436
NZ_CP054018.1\|WP_004005154.1\|1631264_1631918_+\|LppP/LprE-family-lipoprotein	unknown	unknown	gnl\|CDD\|379436
NZ_CP054018.1\|WP_004005150.1\|1628440_1628779_+\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224601
NZ_CP054018.1\|WP_037231086.1\|1620146_1621646_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|223903
NZ_CP054018.1\|WP_004005137.1\|1616564_1617239_-\|pyroglutamyl-peptidase-I	unknown	unknown	gnl\|CDD\|238279
NZ_CP054018.1\|WP_004005152.1\|1629820_1630321_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_CP054018.1\|WP_037231091.1\|1627572_1628448_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_CP054018.1\|WP_004005139.1\|1617790_1618336_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|129813
NZ_CP054018.1\|WP_080513862.1\|1611149_1612088_-\|NUDIX-domain-containing-protein	unknown	unknown	gnl\|CDD\|239521
NZ_CP054018.1\|WP_004005156.1\|1632875_1633556_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NZ_CP054018.1\|WP_004005148.1\|1626936_1627401_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|376823
NZ_CP054018.1\|WP_004005155.1\|1632379_1632796_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226720
NZ_CP054018.1\|WP_004005135.1\|1612203_1614375_-\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_CP054018.1\|WP_004005147.1\|1626165_1626822_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227339
NZ_CP054018.1\|WP_037231093.1\|1628788_1629742_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215

Protein	Function_ID	Function_description	E-value
NZ_CP054018.1\|WP_004005140.1\|1618496_1618973_-\|NUDIX-domain-containing-protein	gnl\|CDD\|240046	cd04690, Nudix_Hydrolase_31, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	9.98617e-38
NZ_CP054018.1\|WP_168160742.1\|1630889_1631228_+\|LppP/LprE-family-lipoprotein	gnl\|CDD\|379436	pfam14041, Lipoprotein_21, LppP/LprE lipoprotein. The family includes putative lipoproteins LppP and LprE from species of Mycobacterium. LppP is required for optimal growth of M. tuberculosis.	3.30606e-21
NZ_CP054018.1\|WP_004005150.1\|1628440_1628779_+\|AzlD-domain-containing-protein	gnl\|CDD\|224601	COG1687, AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) [Amino acid transport and metabolism].	2.10444e-13
NZ_CP054018.1\|WP_004005136.1\|1614784_1616455_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_CP054018.1\|WP_004005141.1\|1619015_1619393_-\|DUF488-family-protein	gnl\|CDD\|225730	COG3189, COG3189, Uncharacterized conserved protein [Function unknown].	6.39185e-47
NZ_CP054018.1\|WP_004005154.1\|1631264_1631918_+\|LppP/LprE-family-lipoprotein	gnl\|CDD\|379436	pfam14041, Lipoprotein_21, LppP/LprE lipoprotein. The family includes putative lipoproteins LppP and LprE from species of Mycobacterium. LppP is required for optimal growth of M. tuberculosis.	5.81323e-10
NZ_CP054018.1\|WP_037231086.1\|1620146_1621646_-\|amino-acid-permease	gnl\|CDD\|223903	COG0833, LysP, Amino acid transporters [Amino acid transport and metabolism].	0
NZ_CP054018.1\|WP_004005137.1\|1616564_1617239_-\|pyroglutamyl-peptidase-I	gnl\|CDD\|238279	cd00501, Peptidase_C15, Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from proteolysis by other proteases until the pGlu is removed by a PGP. PGPs are cysteine proteases with a Cys-His-Glu/Asp catalytic triad. Type I PGPs are found in a wide variety of prokaryotes and eukaryotes. It is not clear whether the functional form is a monomer, a homodimer, or a homotetramer.	9.84332e-60
NZ_CP054018.1\|WP_004005152.1\|1629820_1630321_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	1.55113e-92
NZ_CP054018.1\|WP_037231091.1\|1627572_1628448_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	4.1461e-45
NZ_CP054018.1\|WP_004005139.1\|1617790_1618336_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|129813	TIGR00730, LOG_family_protein_YJL055W, TIGR00730 family protein. This model represents one branch of a subfamily of proteins of unknown function. Both PSI-BLAST and weak hits by this model show a low level of similarity to and suggest an evolutionary relationship of the subfamily to the DprA/Smf family of DNA-processing proteins involved in chromosomal transformation with foreign DNA. Both Aquifex aeolicus and Mycobacterium leprae have one member in each of two branches of this subfamily, suggesting that the branches may have distinct functions. [Hypothetical proteins, Conserved].	1.84222e-51
NZ_CP054018.1\|WP_080513862.1\|1611149_1612088_-\|NUDIX-domain-containing-protein	gnl\|CDD\|239521	cd03429, NADH_pyrophosphatase, NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for activity. Members of this family are also recognized by the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as a metal binding and catalytic site. A block of 8 conserved amino acids downstream of the nudix motif is thought to give NADH pyrophosphatase its specificity for NADH. NADH pyrophosphatase forms a dimer.	1.13207e-44
NZ_CP054018.1\|WP_004005156.1\|1632875_1633556_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.34903e-12
NZ_CP054018.1\|WP_004005148.1\|1626936_1627401_-\|OsmC-family-protein	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	9.97623e-11
NZ_CP054018.1\|WP_004005155.1\|1632379_1632796_+\|membrane-protein	gnl\|CDD\|226720	COG4270, COG4270, Predicted membrane protein [Function unknown].	1.47678e-13
NZ_CP054018.1\|WP_004005135.1\|1612203_1614375_-\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	9.63683e-57
NZ_CP054018.1\|WP_004005147.1\|1626165_1626822_+\|hypothetical-protein	gnl\|CDD\|227339	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism].	0.00994293
NZ_CP054018.1\|WP_037231093.1\|1628788_1629742_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	8.02922e-39

>NZ_CP054018.1|WP_037231086.1|1620146_1621646_-|amino-acid-permease
MAQTSQQSSPASDASDAAADTDLKRGLSARHMQMIAIGGAIGTGLFVASGKTISTAGPGGAIVAYGLIGIMVLFLMQSLGEMAAHLPVPGSFQTYATRYVSSSFGFAMGWNYWFNWAITVAAELVAVGEVMKYWLPETPSWVWAGIFLVLLTGLNALSAKAYGEGEFWLATIKVVTVIVFLIAGIAMIFGVLGGASPGTSNWTTGEAPFVGGPVAIFAIFMVAGFSFQGTEMIGIAAGESKNPRRDVPRALTSVFWRIMLFYIGAMVIIGFLIPYTDPNLLTAAEGDINISPFTLIFERAGIAFAAAAMNAVILTAVLSAGNSGLYVSARMLFSLAQEGKAPKIFTKVNKGGVPMPALMATSAVGAIGFIASVISPDAAYLWLVNVSGLAGFITWVGIAVAHYRFRRAYMRQGHNLNDLPYTAPFFPVGPIIAFIMCLLVIGGQNYEAILAGDWVGVMSSYIGLPVFVAVWAIHAIVTRDRLIPLEQVDVSGLEVKTSK
>NZ_CP054018.1|WP_004005141.1|1619015_1619393_-|DUF488-family-protein
MDIVIKRIYEEPSPDDGYRVLVDRLWPRGVSKDKAHLDEWAKDLAPSTEARRDFGHKPENFESFKQRYLNELDSNSEVYPELERMVAGAQKLQSSRVTLLYGAKSPTCNHAVILRDYLIDRLKSL
>NZ_CP054018.1|WP_004005140.1|1618496_1618973_-|NUDIX-domain-containing-protein
MVDEHSAIDTAQRIVHVSAVVIRNHAGHVLTVRKAASHGFMMPGGKPDAGESPLHTAVREVTEELGFAPDPAQMVYLGKFDAPALNESGFVVGAETFEYMPHPQEEKILEQLSPHAEIAELRWVDPAADYTDQAPLNTECIFPLICRISPGETPSVPL
>NZ_CP054018.1|WP_004005139.1|1617790_1618336_-|TIGR00730-family-Rossman-fold-protein
MRDSFNLAVYCGATMGNDPDFAACARELGTLCAKRGVGVVYGGGRTGLMGTVAGATLDAGGKVYGVVTHQLVEWEGVYPGQTTLDIVDTMHQRKIAMINKADAFVAMPGGPGTLEEFFEVFSWQFLKIHTKPVALLNVNGYWDKLVEAMQYMASTELLRPSYLERLIVVDTPEELMKVLGK
>NZ_CP054018.1|WP_004005138.1|1617275_1617695_+|hypothetical-protein
MARTHHHKEEPVFLLQDTPDALREIGVDDEQEALAAVREPAQALEGASFLQAVGRFYRFYTLGRGHASRSEVLWALLYLTLTTGAVLGLTVYLGMLSEDPHMESLIRVLYMLMMTLTPVWIIVHILPLSSLLSRARGKN
>NZ_CP054018.1|WP_004005137.1|1616564_1617239_-|pyroglutamyl-peptidase-I
MTKTLLITYFGPFPGVSVNPSGVTARQVADVLADESAVRVVTREVPVSYAGSSEALGEMLTDIRPDAVLSLGVAVGRDKVSFEKVAINLDSADIEDNDGVVRVDEAIAPEGREAYFSTLPVRASYERLRGVGLPVEISYTAGTYVCNHVFYEVHRILERQGRRIPAGFVHIPATQVDHEPSDAQTTFTAHADAGGVESESVPTLPEAVVARIVAELVRDTLKVM
>NZ_CP054018.1|WP_004005136.1|1614784_1616455_+|glucose-6-phosphate-isomerase
MTITNPTTTSAWSALTQHKASLTPNLRAWFEQDPSRAQKFSFDAADLHVDLSKNLITEETVQLLLKLAEEVNLAERRDAMFTGEHINVTEDRAVLHTALRRPKGYSPALIVDGQDVDSDVHAVLNKIYAFADRVRSGEWTGVSGKRIETVVNIGIGGSDLGPVMVYEALKPYADAGISARFISNIDPTDVAEKVSDLDPETTLFIVASKTFGTLETLTNARVARDWLLTALGEANALQGKTAEEAVAQHFIAVSTALDKVAAFGIDPENAFGFWDWVGGRYSVDSAIGTSLAIVFGPKVFEEFLAGFHAMDEHFRTAPFEKNVPVLMGLLNVWYVNFLGAETHAVLPYDQYLHRFPAYLQQLTMESNGKSVRADGSFVDYSTGEVFWGEPGTNGQHAFYQLIHQGTRLIPADFLAFANPAHPTKDGEQDVHELFLANFFAQTQALAFGKTEDEVRAEGTAEHVVNARIFSGNRPSTSIMASRLTPRVLGELIALYEHITFVQGIVWGIDSFDQWGVELGKKLALDLVPAIKGDREVLARQDSSTASLIDYYLKHRK
>NZ_CP054018.1|WP_004005135.1|1612203_1614375_-|acyltransferase
MPINPLQGIRVPAAEHTPPYESFLDSRGFRPEIQGLRAFAVLLVVLYHVWIGKVSGGVDVFLFISAFLLSLSFMRKINEGKPLNLLAYWTHVFARLLPAAAVVIVLTLAASLTILPALYWNARAVDAQASLFYYQNWNLANGAVNYFAQGISDKSPFQHFWSLSIQGQIFLLWPILFAVAAFLVHRVRFKPVPAAVTVFGTVFMTSFAFSIWETKQISAYAYFDTRTRLWEFAIGTLLAAMTLKWKPHHVRTRVVMGWVGALGLVTCGAVLPVERTFPGYLALWPVLSGALVMIAGRTDHKFAIDRLLVSTPLQSLGNISYALYLVHWPLLVLYSAAVNKPRVNFLEGTVIIAVSIGLAWVLSTYIEKPLRSRSGVFLDKTVSKLRVTTIFTPTLWVNQLAYILVILLVIGAPVLSVRAWAQQRDITVIQNTEELVKNDEATYPGARAVGTDQMSRVSKPIPQDIPIYGMLADWGEGCPAPFTPVHESLNTSCAVKQNGDDSAPLTIVVGSSHALQMTAAFEPIAQRTGTNQMNLLETGCPYPFAAPEGYLNDRKKRCIAFSQKATEEILRLKPTTVVIIATTTDTSADAETADPNLDETLRVFTDAGIQVIGLRDNPRFAQDMYVCAIRAQGDKSSCSEPIEQKYGDNPAAPIFEKYADRGAYLLDLKDIYCPDGLCRSVIGNVYVYADTNHLTKAFEHTLAETIYERALAAGWKPEGRSGS
>NZ_CP054018.1|WP_080513862.1|1611149_1612088_-|NUDIX-domain-containing-protein
MGGGVKAACGRVETMSVQQNLYLVISRRGETLMNRDGTVHYLPEAPQNTIIETSLEPKFRKPADREGADYHAAYLEDEELLALAEDLSRTNTDALITASQNGFRFYPVHKDPAGRARYAAALAKRDYLLEMEYSAYSGDPALIDGERQVRRTASGELVFPRIEPAVMALVLSRDGERVLLANNRLWHENRFALIAGFVDPGENLEQAVAREVYEETGLQALNLDYRMSDVWPFPRSLMICYRVTVDDTQPVEHLDGEIRAARWFTAPELAQAITESEAIRQKQGVPKLELPGTNAVARRMLDDWLHEKNAGC
>NZ_CP054018.1|WP_004005133.1|1611004_1611163_-|hypothetical-protein
MPGAESKPTKTCAQDKLGQVVHWIGKPEAEARFGAPARERSGMHALISALRI
>NZ_CP054018.1|WP_004005147.1|1626165_1626822_+|hypothetical-protein
MIIIITVAIAIFYLTYDAVRRSREKKLPYVFKRKYHQLEGWLNVTALGLTIDALIIPWDMAWTGTWNTILFGGTALLSANFLYAYEMEYFSIHSDGTIKYHTRTGKIITTHFNCINKYSYSPWGKNFRGGEDISFPDIFHLRTRDDKTAAKFSIKATKEYSIAAHVIFRQEKGRWAHIHSSEDQAQIEEILHDKKAIIQYLTENPQGTDLADDSAHYM
>NZ_CP054018.1|WP_004005148.1|1626936_1627401_-|OsmC-family-protein
MNKAPAEKTIVRRESEDYREVRVERVDRLRYRAHGANGATLDFGVGDGLLTPVELLLAAIAGCSSVDVDAVTTRREIPQVFEVLASALKKHEDGAVRLDDVEVDFDVQFPETEAGTQAAKMVDRLIRLSAEKDCTVSRTVEHPTKVEFHNVNAE
>NZ_CP054018.1|WP_037231091.1|1627572_1628448_+|AzlC-family-ABC-transporter-permease
MKDTAKETSDAEHYAAIGHNPTESGFKQALRASSVVLASFVVLGLGLGVIISAHHLPWWLAPAISLIVYAGSVEFLVVEMIATGASVGAIGFTTLLVNSRHLVYGISFPLQNVKGFWAKLYAIYTLCDESYALNTGPDRNTLSHARILWVSTFLHISWVAGTTAGFFIGASFLSHLEGMDFAMTALFTVLAIDAYRAQRDNVTALLTLISGTVGIILAPGSMLLVSMGTYTALLIVRFFIAKSRGTLPEHQIPAPENNASLTVAEDSTTDQVKTPSTTLTHHDNSQENPHD
>NZ_CP054018.1|WP_004005150.1|1628440_1628779_+|AzlD-domain-containing-protein
MINGHIDSGYIISAVLVAAAVTFVLRVLPFGLKKALAGSEVLDALSHWIPLGAVALLAIYAVSRIDFSSTHTAVPYLAGFVVTALVHLWKKNMVYSMIAGTATCVILINWVF
>NZ_CP054018.1|WP_037231093.1|1628788_1629742_+|AzlC-family-ABC-transporter-permease
MFERSSHPNRHLGEAPQQTSDEQVLDIIASAGLATSSIPVVQEREQALRAGDDALSLELRRTGESGFREAMRAASLVMLGLFFVGIGLGVVIHSLGFPWWLAPLLPGVLFAGSVEFVLLTMMAAGASLVSVAVMTLLINSRHLMYGLSYPIERVHGSLAKFYTVYTLIDEAFALNSGPERHTLRGSRILWIHAGMHMSVILSSTLGFFLGSSFLVHLEGFDFVMTALFTVLALDAYRANPDRLTVLFSVIAAAVALIIAPGSMLLVAMAVYMALLVGRYAAAKKRGSLPQHMLVADELTRHCAEHDRVEETPHEPAQ
>NZ_CP054018.1|WP_004005152.1|1629820_1630321_-|thiol-peroxidase
MAEITFQNNLAVHTSGNLPAVGSKLPAFSVLDADLAEVTGAQFAGKNLVLNIFPSVDTGVCAASVRNFNKEAAGLDNTIVVNVSHDLPFALGRFCAAEGIENVITTSAFRSSFGQDFGVTMTDGPLEGLLARAVVVVNPAGEVVYTELVPEITNEPNYEAALAALK
>NZ_CP054018.1|WP_168160742.1|1630889_1631228_+|LppP/LprE-family-lipoprotein
MPENIPTKNPELNTYDPCAEFSWITMDLKNGTGSSPAHLLFFSHGEFIGVAEQKPFGKFVPHRLSPTSVEVRYVYPKADECNACATGRAISVYTFDPQTRQVSRTGELPPVN
>NZ_CP054018.1|WP_004005154.1|1631264_1631918_+|LppP/LprE-family-lipoprotein
MSRFPVKPLVFCAGAALLLSSCGNPFGASTDSGSSSQAARSSSSSSSSSASTSASASPTHSPTASATSSSASPNPSVSVVTVTANPQPETSTVTVTASSNSNSGSSSSSGRLALDSNASKLRGHHSWSLSSADTSTFDSSAELSWITVGSSDGASHIMLFHHGDYLGTGTLNPIQGSPSVSRNSANQISASVGSSQATFTWDSAQEKIVMNGDLPTG
>NZ_CP054018.1|WP_004005155.1|1632379_1632796_+|membrane-protein
MSLKKNVSEDSRSGGKKHIAPVVTAGFLGTTGVLHFAKPEHYDAIVPRALPGSARFYTYASGAAELGIAGMLTVPTTRRAGALAAIALYTAVFPANVQMAWDWRHESAFKRVVAFGRLPLQLPMIRRAWRIYKTSSRR
>NZ_CP054018.1|WP_004005156.1|1632875_1633556_+|class-I-SAM-dependent-methyltransferase
MSSTRQNPAEQAKALASQLKCPMGDTGQELAHSLNLGNLPMIVSALNALGIEEDDRILEAGPGNGGLLNYVLSLAENLHYDGVEISPLMYEQARAANNVFIAEGLAEYALYDGVNLPYEDGIFTKVLSVNTVYFWEEPAWLLAEMCRVLTAGGRVCLSFCEKDFMKTLPFTKYGFALYDAADIVALTQELPLHTVAVQHLHDMAVAGGSARLVRRDYVNLVLEKEH

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Click the colored protein region to show detailed information

Crispr_ID: NZ_CP054018_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP054018_3

2263176-2263387

TypeV-U4

Consensus_repeat	Method
GGAACCACCCATGCACACGCGGGGCAGAC	PILER-CR
GGAACCACCCATGCACACGCGGGGCAGAC	CRISPRCasFinder
GGAACCACCCATGCACACGCGGGGCAGAC	CRT

3 spacers

c2c9_V-U4

The CRISPR arrays of NZ_CP054018_3

>merge|NZ_CP054018|3|2263176-2263387|PILER-CR,CRISPRCasFinder,CRT
GGAACCACCCATGCACACGCGGGGCAGACTGTACGAGTCTTGGAAGAGGGCATACGCGGGCGGAACCACCCATGCACACGCGGGGCAGACGCTTGCGGTTTTTCGTGAGTTGGCGACTACTGGGAACCACCCATGCACACGCGGGGCAGACTGCTAGAGCTGTCCACGTAGCTGCATGTGTTAGGAACCACCCATGCACACGCGGGGCAGAC

>NZ_CP054018|3|1|2263176-2263387|PILER-CR
GGAACCACCCATGCACACGCGGGGCAGAC	TGTACGAGTCTTGGAAGAGGGCATACGCGGGC
GGAACCACCCATGCACACGCGGGGCAGAC	GCTTGCGGTTTTTCGTGAGTTGGCGACTACTG
GGAACCACCCATGCACACGCGGGGCAGAC	TGCTAGAGCTGTCCACGTAGCTGCATGTGTTA
GGAACCACCCATGCACACGCGGGGCAGAC

>NZ_CP054018|3|3|2263176-2263387|CRISPRCasFinder
GGAACCACCCATGCACACGCGGGGCAGAC	TGTACGAGTCTTGGAAGAGGGCATACGCGGGC
GGAACCACCCATGCACACGCGGGGCAGAC	GCTTGCGGTTTTTCGTGAGTTGGCGACTACTG
GGAACCACCCATGCACACGCGGGGCAGAC	TGCTAGAGCTGTCCACGTAGCTGCATGTGTTA
GGAACCACCCATGCACACGCGGGGCAGAC

>NZ_CP054018|3|1|2263176-2263387|CRT
GGAACCACCCATGCACACGCGGGGCAGAC	TGTACGAGTCTTGGAAGAGGGCATACGCGGGC
GGAACCACCCATGCACACGCGGGGCAGAC	GCTTGCGGTTTTTCGTGAGTTGGCGACTACTG
GGAACCACCCATGCACACGCGGGGCAGAC	TGCTAGAGCTGTCCACGTAGCTGCATGTGTTA
GGAACCACCCATGCACACGCGGGGCAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP054018.1\|WP_071193282.1\|2258412_2258988_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225937
NZ_CP054018.1\|WP_004005759.1\|2260639_2261590_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NZ_CP054018.1\|WP_037231377.1\|2265743_2266331_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NZ_CP054018.1\|WP_004005769.1\|2269884_2270121_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054018.1\|WP_004005764.1\|2265391_2265595_-\|antitoxin-VbhA-family-protein	unknown	unknown	gnl\|CDD\|212155
NZ_CP054018.1\|WP_004005762.1\|2263475_2265098_-\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
NZ_CP054018.1\|WP_037231383.1\|2270262_2271459_-\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_CP054018.1\|WP_037231652.1\|2255641_2256598_-\|DUF2520-domain-containing-protein	unknown	unknown	gnl\|CDD\|227782
NZ_CP054018.1\|WP_004005771.1\|2271820_2272948_-\|zinc-dependent-metalloprotease	unknown	unknown	gnl\|CDD\|274833
NZ_CP054018.1\|WP_037231657.1\|2262960_2263164_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054018.1\|WP_004005761.1\|2262095_2262689_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP054018.1\|WP_037231367.1\|2256688_2258413_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|225962
NZ_CP054018.1\|WP_004005768.1\|2269154_2269706_-\|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|223707
NZ_CP054018.1\|WP_004005772.1\|2273031_2273259_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|213767
NZ_CP054018.1\|WP_172884781.1\|2273522_2273672_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP054018.1\|WP_037231380.1\|2266317_2268588_-\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NZ_CP054018.1\|WP_037231372.1\|2260167_2260602_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|376737
NZ_CP054018.1\|WP_037231655.1\|2259527_2260130_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|238269
NZ_CP054018.1\|WP_037231375.1\|2261853_2262057_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369518
NZ_CP054018.1\|WP_004005758.1\|2258997_2259531_-\|DUF3180-domain-containing-protein	unknown	unknown	gnl\|CDD\|378650

Protein	Function_ID	Function_description	E-value
NZ_CP054018.1\|WP_071193282.1\|2258412_2258988_-\|PH-domain-containing-protein	gnl\|CDD\|225937	COG3402, COG3402, Uncharacterized conserved protein [Function unknown].	8.75789e-18
NZ_CP054018.1\|WP_004005759.1\|2260639_2261590_-\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	1.16483e-101
NZ_CP054018.1\|WP_037231377.1\|2265743_2266331_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	1.89055e-116
NZ_CP054018.1\|WP_004005764.1\|2265391_2265595_-\|antitoxin-VbhA-family-protein	gnl\|CDD\|212155	cd11586, VbhA_like, VbhA antitoxin and related proteins. VbhA is the antitoxin to VbhT. The VbhT toxin of the mammalian pathogen Bartonella schoenbuchensis is responsible for the disruptive adenylation of host proteins. VbhT also induces FIC-domain-mediated growth arrest in bacteria; it is inhibited by this antitoxin which binds to block the ATP binding site of the VbhT FIC domain.	0.00024201
NZ_CP054018.1\|WP_004005762.1\|2263475_2265098_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	5.44118e-30
NZ_CP054018.1\|WP_037231383.1\|2270262_2271459_-\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	4.92383e-65
NZ_CP054018.1\|WP_037231652.1\|2255641_2256598_-\|DUF2520-domain-containing-protein	gnl\|CDD\|227782	COG5495, COG5495, Uncharacterized conserved protein [Function unknown].	1.06973e-50
NZ_CP054018.1\|WP_004005771.1\|2271820_2272948_-\|zinc-dependent-metalloprotease	gnl\|CDD\|274833	TIGR03883, DUF2342_F420, uncharacterized protein, coenzyme F420 biosynthesis associated. A phylogenetic tree of the DUF2342 family (TIGR03624) consists of two major branches. One of these branches, modeled here, is observed almost entirely to be found in coenzyme F420 biosynthesizing species of the Actinobacterial, Chloroflexi and Archaeal lineages. The few organisms having genes within this family and lacking F420 biosynthesis may either have an undiscovered F420 transporter, or may represent F420-to-FMN revertants. This family includes a Chloroflexus Aurantiacus protein whose crystal structure has been determined (PDB:3CMN_A). This has been annotated as a putative hydrolase, but the support for that assertion is untraceable. There is no cofactor present in the structure.	7.70281e-119
NZ_CP054018.1\|WP_037231372.1\|2260167_2260602_-\|dihydroneopterin-aldolase	gnl\|CDD\|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	4.63145e-39
NZ_CP054018.1\|WP_004005761.1\|2262095_2262689_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.45359e-14
NZ_CP054018.1\|WP_037231367.1\|2256688_2258413_-\|PH-domain-containing-protein	gnl\|CDD\|225962	COG3428, COG3428, Predicted membrane protein [Function unknown].	9.23203e-33
NZ_CP054018.1\|WP_004005768.1\|2269154_2269706_-\|hypoxanthine-phosphoribosyltransferase	gnl\|CDD\|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	5.76801e-80
NZ_CP054018.1\|WP_004005772.1\|2273031_2273259_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|213767	TIGR03070, couple_hipB, transcriptional regulator, y4mF family. Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions].	3.1326e-12
NZ_CP054018.1\|WP_037231380.1\|2266317_2268588_-\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP054018.1\|WP_037231655.1\|2259527_2260130_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|238269	cd00483, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a carrier-mediated active transport system. Most microbes and plants lack this system and must synthesize folates de novo from guanosine triphosphate. One enzyme from this pathway is HPPK which catalyzes pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin (HP). The functional enzyme is a monomer. Mammals lack many of the enzymes in the folate pathway including, HPPK.	1.35331e-55
NZ_CP054018.1\|WP_037231375.1\|2261853_2262057_+\|hypothetical-protein	gnl\|CDD\|369518	pfam07787, TMEM43, Transmembrane protein 43. This entry represents the transmembrane protein 43 family of proteins, which may function as tetraspanin-like membrane organizers.	0.00953044
NZ_CP054018.1\|WP_004005758.1\|2258997_2259531_-\|DUF3180-domain-containing-protein	gnl\|CDD\|378650	pfam11377, DUF3180, Protein of unknown function (DUF3180). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.00974e-23

>NZ_CP054018.1|WP_037231657.1|2262960_2263164_+|hypothetical-protein
MSIPREELYTYRVEWSEEDQEFVGTVAEFPSLSCLADSSLDALSGIQQVVLQAIDILEEEGKPVPEP
>NZ_CP054018.1|WP_004005761.1|2262095_2262689_+|GNAT-family-N-acetyltransferase
MPDALTIRPATPYDAQAIARIRVQGWRFAYQGLISQDYLDSLSVAKDTKRMRGYLSQFPQNSPPSRSAPVQSSDGEKRSFMLAVRDDAVLGFCCFSAAPNNADRVERATPGGAMVGRLHSLYIDPGALGQGIGHTLMSHTLSTFAAWGCERANLWVLEGNSRAISFYERQGWRCTGATKVDQSFGPCLVEHEMAVQL
>NZ_CP054018.1|WP_037231375.1|2261853_2262057_+|hypothetical-protein
MNLKVGAWILGFIALAAFITVVLANGLTAVRWVAFGVATCAGFLSLGMVVTLALGWDDPTGTKTDSH
>NZ_CP054018.1|WP_004005759.1|2260639_2261590_-|dihydropteroate-synthase
MHAMMSPQPPAHLPCDAVAAERTLVMGILNVTPDSFSDGGEHYAANDALTHAQRMIAQGADIIDVGGESTRPGAVRISVEEELRRILPVIEGLAETGITISVDTMNAATARAAVAAGAHIINDVSGMSVSDEMIQTVAELGVPYILMHARGTSTTMDALAAYPRGTVTEVLDELAALRDRLVAVGVHAENIIFDPGLGFAKGGMQDWELLAALGQLHTLGHRVLIAGSRKRFLANALNAADAARTKTQNPAAGANTAPDQMPPARAPEDRDAASAALSALVAAQGVWGIRVHNVPPTVDAVTVANTLRTVTRTKQT
>NZ_CP054018.1|WP_037231372.1|2260167_2260602_-|dihydroneopterin-aldolase
MPNPAHAYASCDRITLTGVAAVGFHGALDFEKREGQPFVVDTVLYTDFTQAAATDDLAQTTNYAEVAEIIRTHIVGESLDLIETLAVRIAQNILDECAYVHALEVTVNKPKAPIEVTFGNVAVTVFREREGTQIQGGKGACARG
>NZ_CP054018.1|WP_037231655.1|2259527_2260130_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MDALAHTAVLALGSNLGESETTLEQAAADLVHLSGGAARLVRASGLYVTEPVGGPADQPDYINAILEVRTILDPYALLALCQQVEAHHHRVRLVRWGPRTLDIDVITYDDLVSDDPALTLPHPRAHERAFVLVPWEQANPQAVIPSRDAATGEQTRHLVADLARRVRAADERAGVNAVRFMRDMNLPKNLFDSGAESEGV
>NZ_CP054018.1|WP_004005758.1|2258997_2259531_-|DUF3180-domain-containing-protein
MKPIRISVIACAVALGLVAATILNNLVVNAGGGELAMSPVVALICVVIAGITLWFAFQVARFRNVETRRKAKSMNSLMAARTLACAQGAILTGALLAGWMLGLIVYDVALASARGIPGFFWSTVVNLVGAVLLLAGGLWAQYLCRIPPDDPDGNSSSGGSNSGKLAADGYSRTSDRR
>NZ_CP054018.1|WP_071193282.1|2258412_2258988_-|PH-domain-containing-protein
MSQLSHAEDASFSHEGEGSVTATEGEWVRAHPSYTKIRLIQVVGFFITLVVVFAALTVMFEMMRSSDVLPKTTWLPALTGAIAAVLVVWGIWWAALLPRRTRALGYSLRPNHLMARQGVLFRHVTSIPYGRIQYVDVDSGPLERAHHLVRLTIRTAGVTASKVTLYGIPTERGQQLRELLIRRADERMAAL
>NZ_CP054018.1|WP_037231367.1|2256688_2258413_-|PH-domain-containing-protein
MTQEPRNSNNQDVRSVESSNTSEHHITPDEGAETLTWWRTDVRTFIMNIWVFVAFIIYLAWDYIKNSFKNNAENDYWNILRQLPEYLLNHVGHNPVMLYGYGAAAVLIFGGSILSWAFTRYSVSAHSVYRHSGIFFKKQRQIRLESVQSVDISRSLVARILGLSELRLEAADGAEEALHIKYLSHAKAQNLQERLLRRVSTLRAANRSEFADAVNAPAEKAQEVNPAGEQQTEAGYKPERLLLKVPNLRVLAAIVLSALLWALPVAIIWVSVTIMGWLMNPQKELGQISQFIFPSLIPILGFLWQLWSSFDQGANFTVERIRQNTSDARGDSLRITYGFTGTHTQTLFPQRIQALKIEQPLLWKPFGWYRVVVNIAGVAVNTEGSSDDLFTRNTALPVGTAREMQRLLHLLLPNVSPHSLETVQAVMESSRYNPADSRELGVVTAPRRTRWLNPLTFRRDGFARVNTEQAGVDDQQNRELQTPGHAPTRDLLLLRGGCLLRFLSIVPERQVLAVQWSQGPLNRILKTACISLGSVPGPVKPTVQNLEAHDAERIAAEIIARTDGTRAYYTSPSA
>NZ_CP054018.1|WP_037231652.1|2255641_2256598_-|DUF2520-domain-containing-protein
MTTNHLKPARLGIGVISAGKVGAVLGAALRAAGHSLVGVHAVSEASQERADVLLPGVPLLEVEQIAERSELLLLAVPDDELAGLIEYLASSGSLTSGQLLVHTSGRHGTDIFAPATTLGAIGLAIHPAMTFTGLSLDLQRLTGTSFAVTGPAPFIPIAQALVVEMGGEPVHVAEADRALYHAALAHASNHLVTLLGQSQQMLASIGIEDPARYLGPLVRATVDNALASGEGALTGPVARGDAGTLDAHLNALIEYTDHEKTQDIADSYAAMVRATASRAHNRNLLNDDQKARIESTLRTHTTGTRQSGAMPDDKEFSS
>NZ_CP054018.1|WP_004005762.1|2263475_2265098_-|transposase
MATTDKKDEENLRAYKFRLDPNQAQTTALYQAVGAARYTYNMLTAYNLEVNRLRDDYWKRRHDEDISDADIKKELNALAKEDKRYKQLNYGAFGTQYLTPEKKRHEQAEHRIENGEDPSVVWNQETERSANPWLHTANQRVLVSGLQNASDAWDNFWASRTGKRAGRLVGTPRFKKKGVSRDSFTVPAPEKMGAYGTAYLRGEPAYKQGRRKITDYRHVRLSYLGTIRTFNSTKPLVKAVVAGAKIRSYTVSRNADRWYVSFLVKFSEPIRRSATKRARAAGSVGVDLGVKYLASLSDSEAPQRFPNLKFVEGLPSLENPRWSEASSRRLHKLQRALARSQKGSNRRSRLVKQIARLHHMTALRRESNLHQLTKKLATEYTLVGFEDLNVSGMTASAKGTVENPGKNVAQKSGLNRVVLDAAFGVFRNQLEYKAVWYGSAFEKVDRYFASSQTCSECGRKAKTKLTLRDRVFDCAYCGNMMDRDLNAAVNICREAQRLFDEKLASEDRESLNGRGSRGALRGAETVEASRPPASHRRGSP
>NZ_CP054018.1|WP_004005764.1|2265391_2265595_-|antitoxin-VbhA-family-protein
MTHILSGARITAPEAKENQVFADAALALAGHHVTDPVLKDIVARAAHHEITADEAIAEIRRHVQRAS
>NZ_CP054018.1|WP_037231377.1|2265743_2266331_-|GTP-cyclohydrolase-I-FolE
MSEDNGSGVDKPRIEAAVREILLAIGEDPDRDGLQNTPARVARAYEEFFSGLHADPADVLGTTFDIAHSEMVLVKDIPFYSMCEHHLVPFHGVAHVGYIPGADGKVTGLSKLARVLEVYARRPQVQERLTTQVVEALEEHLSPRGAIVVIEAEHMCMSMRGVRKPGAKTVTSAVRGQLKNAATRAEAMSLIFSKH
>NZ_CP054018.1|WP_037231380.1|2266317_2268588_-|ATP-dependent-zinc-metalloprotease-FtsH
MAQKSNNSPNGPDNFLGRLINGRWLWAIVIAIVVVAFSLSSLFAQGARQVDTNVGLQLLNDHQVKSAKIYDGDQRVELQLKEDYKQGSNNYGSSVKFYYVQPRAEEVVRAMNGAQLESYTDQPVENSFLGSLISLLLPVLLFGAIFWLLMGRMGGNSSVMSFAKSRAKKFNKDNPTVRFSDVAGVDEALAELEEVREFLAEPEKFTRLGAKIPKGVLLYGPPGTGKTLLAKAVAGEAGAPFYSISGSDFVEMFVGVGASRVRDLFKEAKSNPAAIVFVDEIDAVGRRRGVGMGGGNDEREQTLNQLLVEMDGFDGNSNVIVIAATNRPDVLDPALLRPGRFDRQIGVDAPDMKGRQRILEVHAAGKPIDRRVDLGQVAKRTPGFTGADLANVMNEAALLTARDNGNVIDDRAIDEAIDRVMAGPQRTSRIMSEHERKVTAYHEGGHALVAAALRNSAPVTKITILPRGRALGYTMVMPQDDKYSTTRHELLDQMAYAMGGRAAEEIVFHDPSTGAANDIQKASDTARKMVADYGMSALLGSVKLGSDDTEPFMGGDPSAARNYSDKTAYKIDIEVRKLLEEAHDEAFQILVENRDVLDRLAFALLEKETLLENEIAEIFKDVRKRPEREHWYSKEGRERTDIPPVKAPSELAAEKNGLESDSDPTVAMKAPTTASMPTAPEHTAPGQNLPGQGGQPQQMPHPGTQDMEDTDPTVAMPPQQYPEQQQYPGQQNEQQQNPYPYNNPNQNPYGGSDERG
>NZ_CP054018.1|WP_004005768.1|2269154_2269706_-|hypoxanthine-phosphoribosyltransferase
MQAQDVQDDLKNVLFTKEEINAKVAELAARIDEDYEGKDVLLVGVLKGAIMVMADLSRALKGHYTMDWMAVSSYGSGTKSSGVVRILKDLDTDLTGRNVLIVEDIIDSGLTLAWLQQNLKSRGAESVEICTLLRKPKVVKTDVQVKYVGWDIEPEFVVGYGLDFAEKYRNLDCVATLHPHVYS
>NZ_CP054018.1|WP_004005769.1|2269884_2270121_-|hypothetical-protein
MGLFGSDKNPRAELAVLFAKADEPMEAAIDWARSVADKAGLDPAKDEVQLIRELRRTELNLDLKTATYLAEQTAKAVR
>NZ_CP054018.1|WP_037231383.1|2270262_2271459_-|tRNA-lysidine(34)-synthetase-TilS
MQHGRQGRLHPAVGKARRELARALTNLLGEGAIKGTGRARRGSTVSQQGAETEKPLVLVACSGGPDSLALACIAAHFARRSDVRVGAVVVDHGLQADSAEVAASTAETLTNLGLHPVLTERVQVPQGSMGPEMAARTARYGAFERAVHNTGARAVLLGHTLDDQAETVLLGLGRGSGTRSLAGMPPVRIENGVTYLRPFLALRRADMLNICEAEGVAPWNDPTNTDQTLMRARIRHTILPFLQEHLGGDVALSLARTAAVAGPDAEYLDALAAAEYARLKLPAGVHLPDIPGADTVPGNHSTDAAPEKPTPTVIALNRAETAALHSALRMRVLAMATRAAQGENPGFERLQALDEFVAEHATAGPVQLPGHVSAYRRRKVHDPRTDTRVDALVLVSQR
>NZ_CP054018.1|WP_004005771.1|2271820_2272948_-|zinc-dependent-metalloprotease
MSENNTQNLLNVERIAKIVGSLAPAGPRMKPQEMAGVVASLRKAAEESVDHVHRITGLDAAQDLRDSEVLVVDRSTWAKANAQAFSIMLVPFVKPAFEKIQQKKPHADLNKLQEGLAFEVGAVLSFLSTKVLGQYEPYAALAGYGQPGGRLMLLAPNVVSVERELNVEPEDFRLWVCLHEQTHRVQFAAAPWLRDYFLAKITELGDSAASTFDLKDAFRAAAQARAEEPGQGRAHPVKEATAKARKIASELTAIMSLLEGHANVVMDAVDAQIVPTVKTIRRRFNRRSSTQKFLTKLIYRLLGMNKKMAQYRDGQKFVQHIVDAVGMERFNVVWERPENLPTEREIHNPDAWIKRVLDEDAKVVVAGGGDEENTA
>NZ_CP054018.1|WP_004005772.1|2273031_2273259_-|helix-turn-helix-transcriptional-regulator
MAFHAEEFAQNFGQRVRRIRKEERLTQLELSYMVGVSDKTIRDIERGKPGPSFGSVLKTAEVLGIYLVVEGADHA
>NZ_CP054018.1|WP_172884781.1|2273522_2273672_-|hypothetical-protein
MTREMIGEAAQERAETMQKNAEVDAPAVKDLFLPGNRYRMPLDHNERRS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP054018_2	2.1\|1624625\|36\|NZ_CP054018\|CRISPRCasFinder	1624625-1624660	36	NZ_CP054018.1	1624685-1624720	1	0.972

1. spacer 2.1|1624625|36|NZ_CP054018|CRISPRCasFinder matches to position: 1624685-1624720, mismatch: 1, identity: 0.972

tatcgggagtgtcagggtgatcgctgtcgtgatcac	CRISPR spacer
tatcgggagtgtcagggtgatcactgtcgtgatcac	Protospacer
**********************.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1238351 : 1246823

Staphylococcus_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004004791.1\|1238351_1240025_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.1e-101	40.8
WP_004004792.1\|1240237_1241278_-	zinc-dependent alcohol dehydrogenase family protein	A0A2P1EIJ9	Megavirus	1.7e-05	26.5
WP_004004793.1\|1241458_1241839_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_004004795.1\|1242020_1242515_-	hypothetical protein	NA	NA	NA	NA
WP_004004796.1\|1242738_1243716_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A160DHK0	Gordonia_phage	9.2e-142	78.9
WP_037230970.1\|1243842_1246023_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	3.1e-206	51.1
WP_004004798.1\|1245995_1246526_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	2.3e-14	35.7
WP_004004799.1\|1246595_1246823_-	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	5.6e-18	56.8

DBSCAN-SWA_2

2228718 : 2272948

Gordonia_phage(18.18%)

transposase,integrase,tRNA,protease

attL 2221299:2221314|attR 2261231:2261246

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2221299:2221314	attL	NA	NA	NA	NA
WP_172884779.1\|2228718_2229324_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_004005732.1\|2229328_2229811_-	HNH endonuclease	A0A0P0ICV0	Acinetobacter_phage	3.3e-07	41.1
WP_004005733.1\|2229932_2230346_-	hypothetical protein	NA	NA	NA	NA
WP_004005734.1\|2230456_2230798_-	hypothetical protein	NA	NA	NA	NA
WP_004005735.1\|2230808_2231168_-	hypothetical protein	NA	NA	NA	NA
WP_004005736.1\|2231171_2231858_-	AAA family ATPase	A2I303	Vibrio_virus	2.8e-12	31.3
WP_037231355.1\|2232454_2233261_-\|integrase	tyrosine-type recombinase/integrase	A0A2P1CCU8	Gordonia_phage	6.7e-29	35.0
WP_037231357.1\|2233907_2234690_-	class F sortase	NA	NA	NA	NA
WP_050749232.1\|2234785_2236210_+	hypothetical protein	NA	NA	NA	NA
WP_037231359.1\|2236374_2238807_+	DUF11 domain-containing protein	NA	NA	NA	NA
WP_004005741.1\|2239144_2240392_+	FUSC family protein	NA	NA	NA	NA
WP_004005742.1\|2240557_2241205_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004005743.1\|2241282_2242695_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004005744.1\|2242799_2244227_-	DNA repair protein RadA	NA	NA	NA	NA
WP_172461389.1\|2244343_2245417_+	DNA integrity scanning protein DisA	NA	NA	NA	NA
WP_050749233.1\|2245560_2246340_-	hypothetical protein	NA	NA	NA	NA
WP_172884780.1\|2246474_2247410_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_004005748.1\|2247538_2248306_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004005749.1\|2248382_2248892_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004005750.1\|2249073_2251626_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.4e-133	41.6
WP_004005751.1\|2252172_2252532_-	Lsr2 family protein	A0A160DF84	Gordonia_phage	1.4e-10	35.6
WP_004005752.1\|2252705_2252921_-	hypothetical protein	NA	NA	NA	NA
WP_037231362.1\|2253069_2254653_-\|tRNA	lysine--tRNA ligase	A0A2K9L3L6	Tupanvirus	3.4e-69	35.3
WP_037231365.1\|2254697_2255645_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_037231652.1\|2255641_2256598_-	DUF2520 domain-containing protein	NA	NA	NA	NA
WP_037231367.1\|2256688_2258413_-	PH domain-containing protein	NA	NA	NA	NA
WP_071193282.1\|2258412_2258988_-	PH domain-containing protein	NA	NA	NA	NA
WP_004005758.1\|2258997_2259531_-	DUF3180 domain-containing protein	NA	NA	NA	NA
WP_037231655.1\|2259527_2260130_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_037231372.1\|2260167_2260602_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_004005759.1\|2260639_2261590_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	6.2e-26	31.9
2261231:2261246	attR	NA	NA	NA	NA
WP_037231375.1\|2261853_2262057_+	hypothetical protein	NA	NA	NA	NA
WP_004005761.1\|2262095_2262689_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_037231657.1\|2262960_2263164_+	hypothetical protein	NA	NA	NA	NA
WP_004005762.1\|2263475_2265098_-\|transposase	transposase	Q2Z144	Pseudomonas_phage	3.7e-26	35.4
WP_004005764.1\|2265391_2265595_-	antitoxin VbhA family protein	NA	NA	NA	NA
WP_037231377.1\|2265743_2266331_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.1e-44	53.4
WP_037231380.1\|2266317_2268588_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	5.5e-105	42.5
WP_004005768.1\|2269154_2269706_-	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	5.8e-08	27.5
WP_004005769.1\|2269884_2270121_-	hypothetical protein	NA	NA	NA	NA
WP_037231383.1\|2270262_2271459_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_004005771.1\|2271820_2272948_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP054018

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection