CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053618	Achromobacter xylosoxidans strain GN008 chromosome, complete genome	7 crisprs	csa3,DEDDh,WYL,PD-DExK,cas3,DinG	0	0	4	0

1. NZ_CP053618

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053618_1

• CRISPR_ID: NZ_CP053618_1
• CRISPR_location: 204089-204190
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_1

Consensus_repeat	Method
TTTTCATCGCCGAGCCGCCTCAAGAT	CRISPRCasFinder

spacers of NZ_CP053618_1

>1.1|204115|50|NZ_CP053618|CRISPRCasFinder
GAAAAATGCCCCCTCGGGGGCAGCAAGCCGAAGGCGCGGCGTGGGGGCCC

CRISPR arrays and Neighbor proteins around NZ_CP053618_1

CRISPR arrays

The CRISPR arrays of NZ_CP053618_1

>merge|NZ_CP053618|1|204089-204190|CRISPRCasFinder
TTTTCATCGCCGAGCCGCCTCAAGATGAAAAATGCCCCCTCGGGGGCAGCAAGCCGAAGGCGCGGCGTGGGGGCCCTTTTCATCGCCGAGCCGCCTCAAGAT

>NZ_CP053618|1|1|204089-204190|CRISPRCasFinder
TTTTCATCGCCGAGCCGCCTCAAGAT	GAAAAATGCCCCCTCGGGGGCAGCAAGCCGAAGGCGCGGCGTGGGGGCCC
TTTTCATCGCCGAGCCGCCTCAAGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_173010352.1|200096_201026_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NZ_CP053618.1|WP_173010355.1|208945_210475_+|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_CP053618.1|WP_173010354.1|206313_207813_+|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl|CDD|273830
NZ_CP053618.1|WP_024069789.1|196542_197526_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270296
NZ_CP053618.1|WP_081247790.1|207863_208946_+|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|185090
NZ_CP053618.1|WP_173011228.1|199091_199979_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187627
NZ_CP053618.1|WP_173010353.1|201332_204038_+|aconitate-hydratase-AcnA	unknown	unknown	gnl|CDD|236445
NZ_CP053618.1|WP_102949912.1|205322_206210_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176149
NZ_CP053618.1|WP_024069797.1|210510_211215_+|siderophore-interacting-protein	unknown	unknown	gnl|CDD|99790
NZ_CP053618.1|WP_173010357.1|214411_215527_+|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	unknown	unknown	gnl|CDD|378385
NZ_CP053618.1|WP_026383342.1|213199_214402_+|DUF2863-family-protein	unknown	unknown	gnl|CDD|371362
NZ_CP053618.1|WP_173010351.1|194530_195505_-|pirin-family-protein	unknown	unknown	gnl|CDD|224655
NZ_CP053618.1|WP_054516192.1|211250_212141_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176114
NZ_CP053618.1|WP_006387147.1|192043_194245_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|238657
NZ_CP053618.1|WP_173010350.1|191214_191982_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_CP053618.1|WP_051429104.1|197583_199023_-|AMP-binding-protein	unknown	unknown	gnl|CDD|236215
NZ_CP053618.1|WP_006387145.1|195623_196532_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|184959
NZ_CP053618.1|WP_024069793.1|204207_205170_-|DUF4892-domain-containing-protein	unknown	unknown	gnl|CDD|143586
NZ_CP053618.1|WP_173010349.1|190222_191218_+|NAD(P)H-quinone-oxidoreductase	unknown	unknown	gnl|CDD|176180
NZ_CP053618.1|WP_173010356.1|212181_212955_-|dioxygenase	unknown	unknown	gnl|CDD|153375

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_173010352.1|200096_201026_+|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.24049e-56
NZ_CP053618.1|WP_173010355.1|208945_210475_+|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.14565e-126
NZ_CP053618.1|WP_173010354.1|206313_207813_+|efflux-transporter-outer-membrane-subunit	gnl|CDD|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	2.98956e-66
NZ_CP053618.1|WP_024069789.1|196542_197526_-|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl|CDD|270296	cd13578, PBP2_Bug27, Aromatic solutes transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. Bug27 binds non-carboxylated solute nicotinamide, in contrast to BugD (aspartic acid transporter) and BugE (glutamate transporter) which both bind aliphatic carboxylated ligands. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity.	1.81934e-127
NZ_CP053618.1|WP_081247790.1|207863_208946_+|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl|CDD|185090	PRK15136, PRK15136, multidrug efflux MFS transporter periplasmic adaptor subunit EmrA.	7.10952e-104
NZ_CP053618.1|WP_173011228.1|199091_199979_-|SDR-family-oxidoreductase	gnl|CDD|187627	cd05369, TER_DECR_SDR_a, Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR. TTER is a peroxisomal protein with a proposed role in fatty acid elongation. Fatty acid synthesis is known to occur in the both endoplasmic reticulum and mitochondria; peroxisomal TER has been proposed as an additional fatty acid elongation system, it reduces the double bond at C-2 as the last step of elongation. This system resembles the mitochondrial system in that acetyl-CoA is used as a carbon donor. TER may also function in phytol metabolism, reducting phytenoyl-CoA to phytanoyl-CoA in peroxisomes. DECR processes double bonds in fatty acids to increase their utility in fatty acid metabolism; it reduces 2,4-dienoyl-CoA to an enoyl-CoA. DECR is active in mitochondria and peroxisomes. This subgroup has the Gly-rich NAD-binding motif of the classical SDR family, but does not display strong identity to the canonical active site tetrad, and lacks the characteristic Tyr at the usual position. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	1.16558e-110
NZ_CP053618.1|WP_173010353.1|201332_204038_+|aconitate-hydratase-AcnA	gnl|CDD|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NZ_CP053618.1|WP_102949912.1|205322_206210_-|LysR-family-transcriptional-regulator	gnl|CDD|176149	cd08460, PBP2_DntR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold. This CD includes an uncharacterized LysR-type transcriptional regulator similar to DntR, NahR, and LinR, which are involved in the degradation of aromatic compounds. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.2876e-69
NZ_CP053618.1|WP_024069797.1|210510_211215_+|siderophore-interacting-protein	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	7.80577e-39
NZ_CP053618.1|WP_173010357.1|214411_215527_+|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	gnl|CDD|378385	pfam10093, EarP, Elongation-Factor P (EF-P) rhamnosyltransferase EarP. This entry includes family members such as EarP enzymes which are essential for post-translational activation of elongation factor P(EF-P). It was identified as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-beta-L-rhamnose as donor substrate. This was further confirmed for Pseudomonas aeruginosa, Pseudomonas putida, and Neisseria meningitidis. As for S. oneidensis and P. aeruginosa, EarP enzyme acts as an inverting glycosyltransferase, thus mediating the formation of an alpha-L-rhamnosidic linkage. Structural analysis show that EarP is composed of two opposing domains with Rossmann folds, thus constituting a B pattern-type glycosyltransferase (GT-B) and provide basis for arginine glycosylation by EarP. Mutational analysis of efp and earP genes, resulted in a substantial decrease in the production of rhamnolipids and pyocyanin (important factors for colonization and invasion during infection) of P. aeruginosa. Collectively this indicates that EarP and EF-P are essential for P. aeruginosa pathogenicity.The protein family is also annotated in the CaZy Database as GT104.	2.19719e-175
NZ_CP053618.1|WP_026383342.1|213199_214402_+|DUF2863-family-protein	gnl|CDD|371362	pfam11062, DUF2863, Protein of unknown function (DUF2863). This bacterial family of proteins have no known function.	0
NZ_CP053618.1|WP_173010351.1|194530_195505_-|pirin-family-protein	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	1.478e-36
NZ_CP053618.1|WP_054516192.1|211250_212141_+|LysR-family-transcriptional-regulator	gnl|CDD|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.49112e-47
NZ_CP053618.1|WP_006387147.1|192043_194245_-|TonB-dependent-receptor	gnl|CDD|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	3.73232e-108
NZ_CP053618.1|WP_173010350.1|191214_191982_+|SDR-family-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	6.59507e-91
NZ_CP053618.1|WP_051429104.1|197583_199023_-|AMP-binding-protein	gnl|CDD|236215	PRK08276, PRK08276, long-chain-fatty-acid--CoA ligase; Validated.	0
NZ_CP053618.1|WP_006387145.1|195623_196532_+|LysR-family-transcriptional-regulator	gnl|CDD|184959	PRK14997, PRK14997, LysR family transcriptional regulator; Provisional.	1.1118e-62
NZ_CP053618.1|WP_024069793.1|204207_205170_-|DUF4892-domain-containing-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	3.6355e-40
NZ_CP053618.1|WP_173010349.1|190222_191218_+|NAD(P)H-quinone-oxidoreductase	gnl|CDD|176180	cd05276, p53_inducible_oxidoreductase, PIG3 p53-inducible quinone oxidoreductase. PIG3 p53-inducible quinone oxidoreductase, a medium chain dehydrogenase/reductase family member, acts in the apoptotic pathway. PIG3 reduces ortho-quinones, but its apoptotic activity has been attributed to oxidative stress generation, since overexpression of PIG3 accumulates reactive oxygen species. PIG3 resembles the MDR family member quinone reductases, which catalyze the reduction of quinone to hydroxyquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NZ_CP053618.1|WP_173010356.1|212181_212955_-|dioxygenase	gnl|CDD|153375	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine. This subfamily is composed of plant 4,5-DOPA Dioxygenase, the uncharacterized Escherichia coli protein Jw3007, and similar proteins. 4,5-DOPA Dioxygenase catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine (4,5-DOPA). The reaction results in the opening of the cyclic ring between carbons 4 and 5 and producing an unstable seco-DOPA that rearranges to betalamic acid. 4,5-DOPA Dioxygenase is a key enzyme in the biosynthetic pathway of the plant pigment betalain. Homologs of DODA are present not only in betalain-producing plants but also in bacteria and archaea. This enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon.	6.46388e-120

Protein sequences

>NZ_CP053618.1|WP_173010353.1|201332_204038_+|aconitate-hydratase-AcnA
MPHNTLDTLKNFKIGNKSCQYYSLPALGKALGVDVQRLPVSIRIVLESVLRNCDGKKVTEEHVRQLANWQANAKREDEIPFVVARVVLQDFTGVPLLADIAAMRSVADKMGKSPKSIEPLVPVDLVVDHSVMIDYFGTKNALDLNMKLEFKRNQERYQFMKWGMQAFDTFGVVPPGFGIVHQVNLEYLARGVHQDKKNNVYYPDSLVGTDSHTTMINGIGVVGWGVGGIEAEAGMLGQPVYFLTPDVVGVELKGKLRGGVTATDLVLTITEMLRREKVVGKFVEFCGEGTASLSVAERATIGNMAPEYGATMGFFPVDGRTIDYFRGTGRTEDEIAAFEAYFKAQDMFGVPAAQDINYTKLLTLDLSTVAPSLAGPKRPQDRIEIGNVKSTFIDLFSKPVAENGFNQPAEKLQQTFTTSTGTKVKNGDILIAAITSCTNTSNPSVLLAAGLLAKKAVEAGLKVPKHIKTSLAPGSRVVTEYLTKTGLLPYLEKLGFDVAAYGCTTCIGNAGDLTPDLNEVITSNDLVCSAVLSGNRNFEARIHPNIKANFLASPPLVVAYALAGTVTRDLMTEPVGRGKNGDIWLGDIWPTTEEVEALLKYALDPKAFEANYGQVKSNPGKLWENIKGVTGETYNWPDSTYIAEPPFFQGFGMTPGAMPTVKNARALGVFGDSVTTDHISPAGSIKETSPAGKWLKENGVMKADFNSYGSRRGNHEIMMRGTFANVRIKNLMIPARPDGSRFEGGETLFQPTGEQMSIYDAAMKYVAAGTPTVVFGGEEYGTGSSRDWAAKGTQLLGVKAVITRSFERIHRSNLVGMGVLPLQFKGSDSVQSLGITGEETYDISGLENGIKPMQDVTLTITRKDGSKQDVTLLLRIDTPIEVDYYQHGGILPFVLRQLLAA
>NZ_CP053618.1|WP_173010352.1|200096_201026_+|LysR-family-transcriptional-regulator
MTTPPALDLNLIQLFVTIVEAGTLSEAALRQGVTRSHVSRNLQKLERAFGAQLIRRTTRRLELTHEGSVLYDHGARMAREVESARHALQKLGAEPTGHVRLSLPTGLGELNMLRPLLVRFALEHPSLSLRVLFSNRVSDLISSEIDVALRAISVPPQDYVARELGRIKWHLCAAPEYLARMGMPAHPRDLGRFDFLGPPGPRPQATLRLRGKGQPHEVKLATRLQSEYFPFLAQAAREGAGVALLPAYIVRPDLEAGRLLQVLPAYQAEGPGDKLYILTSPTPYPSSAQRALVDFLKRELEPLLRTFLA
>NZ_CP053618.1|WP_173011228.1|199091_199979_-|SDR-family-oxidoreductase
MFRADLFQGQRILITGGGTGLGYAMARQLAALGATVHLCGRRLAVLEQAAQALRGESGGQVHVHPVDIRDAGAVDAMVARIWDQHGGLDALVNNAAGNFISPTEKLSERGFNAIADTVFRGTFYMTQAVGKRWIGSGASGAVVSIVVTWVWTGSPFVVPSAMSKAGIDAMTKSLAVEWGRHGVRLNAIAPGVIPTEGASARLRPNDSGTDALVKQNPMQRLGQGQDIGELAAFLLAPGNDWINGQTIALDGGDYLANGAYFKQYFDWSDEDWAAARAAIEARTAADKAQRSAGQA
>NZ_CP053618.1|WP_051429104.1|197583_199023_-|AMP-binding-protein
MRRGEQVAAGLAAMGIGEGDVVAVLLRNGMPYLEIIQACKRLGCYYCPINWHYTPDEVAYLVRDSGARLLIAEEDLWQAARAALPADLPSRRVGAAAVSEDYASWREAQAPYDGPVVAPRGHMAYTSGTTGRPKGVVRAPFPLDQLAQRLAAVEAVVEQAYGLRPGCRALLPAPVYHSAPSVFAQVALRVCETLVLAPRFDPLEVLRLIERHRIDTVYLVPIMYVRLLKLDPAQRAAFDLSSLRFVASTGAPCAPALKRAMIDWLGPVIHETYASSEAGMVTVIDSHEALARPGSAGRPIGGAQIRIYGDDGALCAPGQIGRIHVRQPAYADFTYRNNPQARSRIERDGLIGLGDLGYLDDDGYLFVCDRESDMVISGGVNIYPAEIEHHLTQYPGVADCAVFGVPDDEFGERLLALVQPAADTALAPEEVLRWLSTRVARYKVPRELRLRQTLPRDDNGKIAKRRLRDAFWAERDRKV
>NZ_CP053618.1|WP_024069789.1|196542_197526_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MFMKNSGIGRAAAALLLCMAAVSPAQAAFPERPVKLVVPYTPGGAADLLSRVLAERLSQELAQPVVVENKPGANTMIAATQVARAQPDGYTLFLASNASMVLNPMLYRKISYDAQRDFRVLSVVAELPLVVVANNSVPASTLAQFVDYARARPGKLNYASVGIGNPLQLATELLKSRTGIDVAHVPYNGSAPALSSLMANDTQLMVDVISTSLPLVRENKIKALAVTGAQRLPVLPDVPTVAESGFAGFRAATWFGVAVPRGTPPAEADRLREAVAAVMRQADFRDRFQAQGLVIQAPRGQAEVDAYLAEDRERWNGVIQANHIRLD
>NZ_CP053618.1|WP_006387145.1|195623_196532_+|LysR-family-transcriptional-regulator
MHSYIHHLDDLLLFTEVVEKGGFSAAARVLNMQRSKLSRRVAELEARLGLRLLQRNTRRVSLTPMGEQIYVHALAMAREARSAFDLAAAMGDTPSGLLRMTAPSALAVTLLGELVARFCLQHPGVRVLLDTRDQVIDLVGEGYDLAFRAQGASLTDSRLVARELAPVPLILVAAPAMARAAPRHPRDLNALPLLAHATQDSPQSWHFVGPAGEAESIEFRPRCLSSNLAALREMARAGLGVALLPHYLCAGSLAKGDLAQLLPAWRAAPARIYAVMPARRGAPLALRRFLDFAAAEMPALLA
>NZ_CP053618.1|WP_173010351.1|194530_195505_-|pirin-family-protein
MTIRLSPPFARPFEPEGDICSYRHFRHSDFPQGMSPLVLVDHFIMTGPAVAPHPHAGISTVTLLLEDTQGGLRIRDSLDNEHEARAGDLHWTVAGRGIVHGHELVGAARLNGLRLYVNLPARLKSMPPSATLVRGWEMPVLQSDAGRVRVVSGRYDGWDAPLATPEPLLILDGWLRPGASRLVPLPAGWNAWLYAAQGELGVRARHETTPPPRPPVEAAPVIPAARFRPAGRAATTGRRAADPDFAVLPPGAALTATADRDGFLQLLAAGAPAHFILVAGAAIDEPVIQRGPFVMTDARALAQAVAAYEAGDFGQLRQESGVPG
>NZ_CP053618.1|WP_006387147.1|192043_194245_-|TonB-dependent-receptor
MKIRTLACVVAALPYTAIVHAQSAAPAADGSVVSMEAIKVEASADASAGGLAQPYAGGQVARGGRVGVLGTQDIMSTPFSVTSYTNELIQDKQARSVGDVLQNDAGVRVARGFGNFQESYFIRGFILSSDDVAYNGLYSLLPRQYIATELFERVEVLRGASAFLTGAAPSGGGIGGVINLVPKRAPNEPLTRFTTGVSSGGQFSVSTDIARRFGPDDSTGIRLNVANRSGDTGIDDEHSRTSLVSLGLDWRSADTRLSADIGWQENKLKRARPNVTLRGVTSVPDAPDASSNYAQPWSYSNERDVFGTVRAEHDFSDKLTGWAAFGMRRSDEANSLGNVTVTNGSTGDGNFYRFDNTREDSVNTGELGLRAKVRTGPVGHEFVASASFFDLKKKNAYVMDYLNTFPTNIYDPVSYDRPAYGSKALFGNDLDDPALQGRTRLSSYAFGDTMSFLDDKVLLTLGIRHQRLSQRDYAYNTGKEQSAYDASRNSPAAGIVFKVAPSVSLYANYIEALVAGDTAPQTANGKPVPNAGQSLQPYVSKQKEIGVKYDGGGLGAGLALFSTDKPRAAYNASNAFTASGKDRHQGIELTVFGEPVNRVRVLGGMTFLDAKQRSTGNSAIDGNRVIGVPRFQANLGAEWDIPGVQGLTVDGRVVYTGASYADDANTLKVPGWTRFDAGLRYMMDVDGHVVTLRARVENIANRNYWSSVGGYPGNGYLVLGGPRTFSLSASMDF
>NZ_CP053618.1|WP_173010350.1|191214_191982_+|SDR-family-oxidoreductase
MSARFQDQVIVVTGAVGGIGSAIVEGFLAEGGKVGLIDFNSQGGQAYEKELKKRGHAVSFVHADVSHFDQCQAAYERITRDLGPATILVNNVGISPKTDGRALKVWEMTPGEWDKVVAVNLNSVFYMTHLATPHMVRQRQGRVINMSSVAGKAYCDIVAAHYAATKAALLGLTRHWAAELGEHDVTVNGLAPGRISTPLLKSVPKEINDAVAEVTALRRLGTPEEVADACLFFASDQARFVTGQVLDVAGGWLMT
>NZ_CP053618.1|WP_173010349.1|190222_191218_+|NAD(P)H-quinone-oxidoreductase
MSLRCTFIDHGTGGAPDCLRLAEREMAAPAGRQVLIEVAYAGVNRPDVLQRSGSYPPPPGASPYLGLEVAGTVIAVGPDATRWQVGDRVCALTPGGGYAQYCLADERHCLPVPRGLDLLSAAAIPENYFTVWTNVFERARLAAGEKFLVHGGSSGIGLTAIQLARAFGAEVWTTVGNQEKAEACLKAGAHHAVIYRDTDFEADIRQATGGQGVDVILDMVGGAYINKNIRLLAVNGRLVQIAFLEGSKAEIDALPIMTKRLSFTGSTLRPRSDEDKGAIAQALADKVLPLMEQGRCLPLIHQVFPLEHAAQAHALMESSKHIGKIMLKVRA
>NZ_CP053618.1|WP_024069793.1|204207_205170_-|DUF4892-domain-containing-protein
MKAHIVKVASLAIVAATLTASPAWAEDVEGSRDHPALTRFEGAEIRAYEHKDYDEALMPDRPVARESEAKGLTLEGKLTRIAYRIDGKKSALEVYRNYQGALQAGGFKTVFECKGDEQCGGDFQSFVLNSGKVSQPGQGDAAFGGKYYVVLAKKEAPTGDIYVFLDVMEDSSNNITPVFQQVIETKPMQTGQVKVLDMAAMQKSLAESGRVAVYGVYFDTDKAEVKAESKAALDEMGKLLNANPKLKVYVVGHTDNQGTLAGNLELSQKRADAVVKALEAGYKIPAARLSARGVASLAPVAANDAEAGRAKNRRVELVAQ
>NZ_CP053618.1|WP_102949912.1|205322_206210_-|LysR-family-transcriptional-regulator
MNLLVALDALLAEGSVTGAAERLQLSVPAMSRTLERIRRMMGDPLFVRAGRGLVPTPRAEALREPVRALVAQARELLAQDAAFDLKTLRRVFTIRADDGAVSTLGPALLDTLAKEAPRVTVRFISQGKQDVLSLREGAIDLDIGVIEDMGPEIVRQRLFPDRFVAVFRPANPLARHRKLTPERFARARHATVSRRGVLSGPVDIELGKVGLARHISAVTHSFAEALAITRKSDLVATVPDLLTLHLRDDLQMRALPFDTPAVTISQAWHPRFNEDPAHRAIRQMVHRISLAISGR
>NZ_CP053618.1|WP_173010354.1|206313_207813_+|efflux-transporter-outer-membrane-subunit
MIHSTRYRPDARPARRMRLRHAPLAAALAALVAVAGCASHDGLRPAGKPLDLAAQDAGQDIAAAVRDTADDAAPWWRAWGDDQLDRLMADALRQAPGVRAAQARLGQAEAVFGSVDANRQPTLDGSATITADRYPGHYTYGAPYADNTGGSGSLLASLRLRLDIWGKWRALADAARLDAEGAALAHADAQLALQQGIAAAYLRLDAAFRLHELARQQRERQRQALELHQTRRQAGLGSDAPVADARGRLARMDAEVERLDREIARQRHALAALAGQAPGYGDALRRPRLALRADPALPAALPARLLGLRPDVLAQRKRLDAADRRIEAAKAEFYPDIDLKAFAGLQSLGLSHLLQGNSLAAGIGPALTLPIFDGGRLRAGLRDRIAGYDLAVADYDATVVRALQEVADGLAGMAQARARRDAARVSLREAGTLARLQAVRASRGLSARQDEIDTDLERLRADSELAAADLDLGLARTALAGALGGRWSPSQSSDNEALK
>NZ_CP053618.1|WP_081247790.1|207863_208946_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MLAGGATLLAGAGWAAWTFLAGAATQTTDNAYVNGHVVAITPQVGGAVSAIWADNADRIRAGQTLVEVDPADTQIALAGARADLARARRRVQALFASRDQAGAEVARRQAELDRAQADVSARRGIAAQGAITSEEARHAADALNAARAALAVAQAAERAAQAQVDGVTPDTHPDVTLAQARLRAAALDAQRTTIRAPVGGMVAQRSVQLGKHVAIGDKLMAVVPLDQMWIDANFKEIQLAGICPGQPAVVTVDAHGAKVRYRGRVGDVMAGSGSAFALLPSQNATGNWIKVVQRVPVRINLDPKELADHPLRIGLSAEVTVDTARCDPAQAGAARGETTDIYRQQRQAADTLAQAGQGLQ
>NZ_CP053618.1|WP_173010355.1|208945_210475_+|DHA2-family-efflux-MFS-transporter-permease-subunit
MSAAPRPIEPMTGLPRVVAAVAISLASFMAVVDITIANVSVPTISGNLGVSPEIGEWAITFFAIANSICIPLTGWLSRRLGQVRLFVLSVAAFTLASVLCGVAQNFESLLAFRVLQGMVSGPIVPLSQALLVAIFPPDKRTLALSMWAMTNMAGPVAGPVLGGWLTDDFSWPWIFLVNAPVGIAVVAVTATMFRGRDTPSTRLPVDLRGLILLAVAIGCLQLTLDRGRTLDWFASPFIVTTALLSALGFVFLVIWELDEAHPIVDLSLFRHRNFAMGTLAVAVGFGLYFAALVLIPLWLQTDMRYTATWAGLATAPMGVFGILLAPLLGRWVQRGDARVFASLAFVAWSLVAWWRASMTTDVGVGLISLACLLQGIGIGLFLTPLVSLSLAGLPPERIAAASGLQTAIRMMAGSLVASLASTYWDERSRYYQNVLVDSATPARPAVQDTLNALAGAGLDEPQSWGVIWNGLKTQADMLALNDFFLWSSLAFALSIALVWLARHPRAAKA
>NZ_CP053618.1|WP_024069797.1|210510_211215_+|siderophore-interacting-protein
MQPFSLPRRDVPCIVLRARDVARDMRRLTLGGPELSAWLARPGVDQPGAWVKVFPPGVPGRAYTLRGIDFEASSVEIDFVVHGDAPGTVSEWARRARPGDAVSIAGPRDGGFSLLADTRWVWLGADASAWPAASRIIESLPGGIQVLGVRHPAGDDDWPAIASARAPQWAARSLPPGGDEPSAPAPDGPGQVWLAGQAAWVKAWRAHWLQRLRFDPARLSAKGYWKAGEQDYKE
>NZ_CP053618.1|WP_054516192.1|211250_212141_+|LysR-family-transcriptional-regulator
MKKELDRMRDMALFVQVAALGSLTRAAESTGVPASTLSRRISEFESQIGVKLLHRSTRRLALTDIGQRYLERITEVVDRARAISGELEEEMGRPTGHLRVCAPVDFNAYFPEAALADYCASHPGVRFELHCSAQLPDLATEPYDICIATTEPPQASRMVRRRIGMAEYQLYAAPAYLRAYGVPAHPAELARHRCVVMPDSESGLALTDGNASAQVALAPLLVLNNQLAVENLLRDGLGIGPLTRGRADALVREGALAPVLPGWTLPPRPILALTASRALPARVRGFIDLLVARVVT
>NZ_CP053618.1|WP_173010356.1|212181_212955_-|dioxygenase
MRWPTLFVSHGSPMLAVEPGATGPALAAWSRSLSRKPGAILVVSPHWMGHGLALSTRDRQVAWHDFGGFPPELYTLQYAAPGSPELAARTQALLAEAGIAADRDPRRPLDHGAWVPLRYLYPEVDVPVVQLSLDMGRDAAGQLELGRALAPLRDEDVLIIGSGSLTHNLRDVRMPQHAPPAPYVPAFQAWYAEHLAANDVPALLDWQARAPGAAQAHPHDDHLMPLYVALGAGGPQVTRLTDEISYGALAMDAYAFD
>NZ_CP053618.1|WP_026383342.1|213199_214402_+|DUF2863-family-protein
MARSRSQSAPRLTRDATRLITLAQSLNRSGSRVEDVYWENQLGEAIPKLLKAGQDAPLEAALDHLAQGDVGAYEVLIEQAETLSESMKIDKNGVRYDILLIVAPVVAWTRYAIPTGPVPAGAQQALLAQLHGHVLSSQARSALMPHLVSVDQMPRTFSETWQWLQRLGSQALGAETTKPALNTEVETANMLADTRYIVAAVAVPEFAPVFRWQEQIGEADASRDACLAQWAAQAQPTLAGLLPGCGFEALLPDAYYVSNREADRRVRPLSLRAAISWLEGAVSLDASQLRAVIAGCGESRVDEYRVSFTARNSNDVYYGCVWPLYGREEDLPADEGQPDVVDEIAALLKEYGVSDVRRIPGVLPPEYCEDCGAPYFPNPLGELVHAELPEDAEAAPAKFH
>NZ_CP053618.1|WP_173010357.1|214411_215527_+|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP
MQADIFCRVVDNYGDIGVCWRLARRLAHGHGWEVRLWVDDLASFARIQPGIDAGLARQAFNGVDIVRWSDAPDPALGARDVVIEAFACDPPEPFLDSMRQRHPAWINLEYLSAEAWVESCHGLPSQRPDGLVKHFYFPGFTPATGGLLREPGLSAERDAFQADTAAQDTFLRGLGVAEAHLSLRHNGARTMSLFCYPDAPVDGLARALAADPQPALLLAPEGVAPGLETACAMPGGPAVARLPFVAQPDFDRVLWCADLNFVRGEDSFVRAAWAARPLVWQIYPQDENIHLEKLDAWLARYPAPETATALMRAWNQPGAGAATAAALAAALAPPAWQAWARAARDWDAAQAARPDLAENLAGFCAELAKKR

Crispr_ID: NZ_CP053618_2

• CRISPR_ID: NZ_CP053618_2
• CRISPR_location: 1655603-1655690
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_2

Consensus_repeat	Method
AGGGGGCGACACCTGCAGACCGG	CRISPRCasFinder

spacers of NZ_CP053618_2

>2.1|1655626|42|NZ_CP053618|CRISPRCasFinder
AGAACGAGATCCACCCCGTACGCGCTCGCGCGCGCCCCCTCA

CRISPR arrays and Neighbor proteins around NZ_CP053618_2

CRISPR arrays

The CRISPR arrays of NZ_CP053618_2

>merge|NZ_CP053618|2|1655603-1655690|CRISPRCasFinder
AGGGGGCGACACCTGCAGACCGGAGAACGAGATCCACCCCGTACGCGCTCGCGCGCGCCCCCTCAAGGGGGCGACACCTGCAGACCGG

>NZ_CP053618|2|2|1655603-1655690|CRISPRCasFinder
AGGGGGCGACACCTGCAGACCGG	AGAACGAGATCCACCCCGTACGCGCTCGCGCGCGCCCCCTCA
AGGGGGCGACACCTGCAGACCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_006390050.1|1647073_1648732_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NZ_CP053618.1|WP_053499537.1|1642101_1642929_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|380379
NZ_CP053618.1|WP_049053005.1|1645372_1645918_+|N-acetyltransferase	unknown	unknown	gnl|CDD|224168
NZ_CP053618.1|WP_020926099.1|1658209_1658854_+|CoA-transferase-subunit-B	unknown	unknown	gnl|CDD|188219
NZ_CP053618.1|WP_024070582.1|1661550_1661919_-|phosphate-starvation-inducible-protein-precursor	unknown	unknown	gnl|CDD|183165
NZ_CP053618.1|WP_024070578.1|1657523_1658213_+|3-oxoacid-CoA-transferase-subunit-A	unknown	unknown	gnl|CDD|131482
NZ_CP053618.1|WP_155867591.1|1659546_1660326_+|3-oxoadipate-enol-lactonase	unknown	unknown	gnl|CDD|131480
NZ_CP053618.1|WP_024070574.1|1653109_1654045_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|235707
NZ_CP053618.1|WP_006390042.1|1655791_1656520_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|181044
NZ_CP053618.1|WP_006390049.1|1649032_1649746_-|7-cyano-7-deazaguanine-synthase-QueC	unknown	unknown	gnl|CDD|284031
NZ_CP053618.1|WP_024070579.1|1659194_1659491_+|YciI-family-protein	unknown	unknown	gnl|CDD|183800
NZ_CP053618.1|WP_173010560.1|1649917_1652764_+|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|234570
NZ_CP053618.1|WP_173010561.1|1654227_1655568_+|short-chain-fatty-acid-transporter	unknown	unknown	gnl|CDD|224942
NZ_CP053618.1|WP_006384641.1|1643372_1644410_+|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|235154
NZ_CP053618.1|WP_020926101.1|1656570_1657353_-|IclR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|131484
NZ_CP053618.1|WP_024070581.1|1660329_1661370_+|cyclase-family-protein	unknown	unknown	gnl|CDD|377240
NZ_CP053618.1|WP_026382245.1|1644357_1645248_-|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176112
NZ_CP053618.1|WP_020926098.1|1658906_1659182_+|muconolactone-Delta-isomerase	unknown	unknown	gnl|CDD|213786
NZ_CP053618.1|WP_006390029.1|1662297_1662633_+|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_047992014.1|1645914_1647096_+|MFS-transporter	unknown	unknown	gnl|CDD|340913

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_006390050.1|1647073_1648732_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.3146e-61
NZ_CP053618.1|WP_053499537.1|1642101_1642929_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.46893e-40
NZ_CP053618.1|WP_049053005.1|1645372_1645918_+|N-acetyltransferase	gnl|CDD|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	2.75759e-61
NZ_CP053618.1|WP_020926099.1|1658209_1658854_+|CoA-transferase-subunit-B	gnl|CDD|188219	TIGR02428, 3-oxoadipate_CoA-transferase_subunit_B, 3-oxoacid CoA-transferase, B subunit. Various members of this family are characterized as the B subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The A subunit represents a different clade in pfam01144.	1.4236e-113
NZ_CP053618.1|WP_024070582.1|1661550_1661919_-|phosphate-starvation-inducible-protein-precursor	gnl|CDD|183165	PRK11505, PRK11505, phosphate starvation-inducible protein PsiF.	9.0957e-19
NZ_CP053618.1|WP_024070578.1|1657523_1658213_+|3-oxoacid-CoA-transferase-subunit-A	gnl|CDD|131482	TIGR02429, 3-oxoadipate_CoA-transferase_subunit_A, 3-oxoacid CoA-transferase, A subunit. Various members of this family are characterized as the A subunits of succinyl-CoA:3-ketoacid-CoA transferase (EC 2.8.3.5), beta-ketoadipate:succinyl-CoA transferase (EC 2.8.3.6), acetyl-CoA:acetoacetate CoA transferase (EC 2.8.3.8), and butyrate-acetoacetate CoA-transferase (EC 2.8.3.9). This represents a very distinct clade with strong sequence conservation within the larger family defined by pfam01144. The B subunit represents a different clade in pfam01144, described by TIGR02428. The two are found in general as tandem genes and occasionally as a fusion.	1.72277e-130
NZ_CP053618.1|WP_155867591.1|1659546_1660326_+|3-oxoadipate-enol-lactonase	gnl|CDD|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	8.6231e-106
NZ_CP053618.1|WP_024070574.1|1653109_1654045_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl|CDD|235707	PRK06130, PRK06130, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	4.74729e-171
NZ_CP053618.1|WP_006390042.1|1655791_1656520_+|SDR-family-oxidoreductase	gnl|CDD|181044	PRK07577, PRK07577, SDR family oxidoreductase.	1.45118e-68
NZ_CP053618.1|WP_006390049.1|1649032_1649746_-|7-cyano-7-deazaguanine-synthase-QueC	gnl|CDD|284031	pfam06508, QueC, Queuosine biosynthesis protein QueC. This family of proteins participate in the biosynthesis of 7-carboxy-7-deazaguanine. They catalyze the conversion of 7-deaza-7-carboxyguanine to preQ0.	1.31463e-87
NZ_CP053618.1|WP_024070579.1|1659194_1659491_+|YciI-family-protein	gnl|CDD|183800	PRK12863, PRK12863, YciI-like protein; Reviewed.	7.0573e-45
NZ_CP053618.1|WP_173010560.1|1649917_1652764_+|phosphoenolpyruvate-carboxylase	gnl|CDD|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NZ_CP053618.1|WP_173010561.1|1654227_1655568_+|short-chain-fatty-acid-transporter	gnl|CDD|224942	COG2031, AtoE, Short chain fatty acids transporter [Lipid metabolism].	7.02554e-138
NZ_CP053618.1|WP_006384641.1|1643372_1644410_+|2-isopropylmalate-synthase	gnl|CDD|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NZ_CP053618.1|WP_020926101.1|1656570_1657353_-|IclR-family-transcriptional-regulator	gnl|CDD|131484	TIGR02431, p-hydroxybenzoate_hydroxylase_transcriptional, beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family. Member of this family are IclR-type transcriptional regulators with similar DNA binding sites, able to bind at least three different metabolites related to protocatechuate metabolism. Beta-ketoadipate is the inducer for PcaR, p-hydroxybenzoate for PobR, and protocatechuate for PcaU. [Regulatory functions, DNA interactions].	6.91897e-126
NZ_CP053618.1|WP_024070581.1|1660329_1661370_+|cyclase-family-protein	gnl|CDD|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	3.13699e-06
NZ_CP053618.1|WP_026382245.1|1644357_1645248_-|LysR-family-transcriptional-regulator	gnl|CDD|176112	cd08420, PBP2_CysL_like, C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold. CysL, also known as YwfK, is a regular of sulfur metabolism in Bacillus subtilis. Sulfur is required for the synthesis of proteins and essential cofactors in all living organism. Sulfur can be assimilated either from inorganic sources (sulfate and thiosulfate), or from organic sources (sulfate esters, sulfamates, and sulfonates). CysL activates the transcription of the cysJI operon encoding sulfite reductase, which reduces sulfite to sulfide. Both cysL mutant and cysJI mutant are unable to grow using sulfate or sulfite as the sulfur source. Like other LysR-type regulators, CysL also negatively regulates its own transcription. In Escherichia coli, three LysR-type activators are involved in the regulation of sulfur metabolism: CysB, Cbl and MetR. The topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.60754e-51
NZ_CP053618.1|WP_020926098.1|1658906_1659182_+|muconolactone-Delta-isomerase	gnl|CDD|213786	TIGR03221, muco_delta, muconolactone delta-isomerase. Members of this protein family are muconolactone delta-isomerase (EC 5.3.3.4), the CatC protein of the ortho cleavage pathway for metabolizing aromatic compounds by way of catechol. [Energy metabolism, Other].	6.49891e-56
NZ_CP053618.1|WP_047992014.1|1645914_1647096_+|MFS-transporter	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.39132e-33

Protein sequences

>NZ_CP053618.1|WP_173010561.1|1654227_1655568_+|short-chain-fatty-acid-transporter
MNKLASFFTELMRKYLPDPFVFAIALTLLTVLLAMGIEGQGIGDVTRAWGKGFWSLLAFTTQMAVILAMGYVLATAPLTDRLLNRIVSHVHKPHTAIIVATLVGGIGSYLNWGFGLVIGGIVAKKLALKVKGVHYPLIIAAAYSGFTMYGLGLSASIPVLVATPGHPTAKQMGIIPLTETIFSVPMLITSLVIIVTLPLLNAWLHPKKGEKIVEVDPAIDRDTSAAGAAEDLLEKGTLASKLNNSRLLSLLIGALGVAYVAFHFIDGGSLDLNLINFIILFLGIILLGTPAAYVAKLTEGIKTISGIILQYPFYAGIMAIMAASGLVTTISKVFVDVATPATLPFWGLISSFVINFFAPSAGGHWVIQGPFMIDAAREIGSALNQTTMAVMLGNAWNDLVQPFWILPALALSKLKLRDVMGYTVIMMLWVGVIHITAVLAWGYLTH
>NZ_CP053618.1|WP_024070574.1|1653109_1654045_+|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MDTPLQNLAVIGAGAMGSGIAALFASKGLDVVLVDPMDGALDRARAVIERQLNVYAPGQVDAVMQRIRMAPGLDAAASCDLVIEAVPENLELKRGLFAQLDALCKPEAIFATNTSGLSINAIASAVARRDRFVGTHFFTPADVIPLVEVVRNDATSEDTVARVMATLRLGGKRPVLVRQDIPGFIANRIQHALAREAISLLEKGVASAEDIDEVVKWSLGIRLALSGPLEQRDMNGIDVHYAIASYLYKDLENRTEPSELLKSKVENGQLGAKSGQGFYTWSAERRERVLRDKSAALGELAAWLNAKAGDS
>NZ_CP053618.1|WP_173010560.1|1649917_1652764_+|phosphoenolpyruvate-carboxylase
MNASRPQSDSAEPLRHDIRLLGRLLGEVIAECEGKRVFDTIETLRRTAVKFRREGNVADGKLLEQRVKHLQGSDPNSVARAFSYFLHLSNIAEDRDQNRSQRARALAGDAPARGSLHDAVQTLGRQGVTPARIRRLLAEACVMPVLTAHPTEVQRKSTLDVHREIAAALTQRDQPLTPEELAELDAALLGRVATLWQTRMLRYTRLTVADEIENALSYYRSTFLQVIPRVYGDLSKLLNRDAKPFGAPPAPLEPFLRMGSWIGGDRDGNPNVDADTLERALLRQATVLFEHYLQEVHALGAELSITTLLIAVDPALLALAEHSGDDSPHRSDEPYRRALVGVYARLAATALRLTGQNLARRSTVAAQPYDTPQELSADLAIIAASLAAHHGAPIGRLRLAGLQQAVEVFGFHLATVDLRQSSDVHERALAELFSRAGVTHAGQPLDYLALDEDARVALLRAELAQARPLASPWIAYSEDTTRELAVLRAAAAGRQRYGRQAVRQTIVSHTETLSDLLEVMVLQKEAGLIAPAGQDIPPEDGLMVVPLFETIPDLQRGADIMAAWLDLPEIRERVKRAQNGAQEVMLGYSDSNKDGGFLTSNWSLYQAERALVDVFSSRHVRLRLFHGRGGSVGRGGGSSFDAILAQPPGTVAGQIRLTEQGEVIQSKYKDAEVGRWHLELLVAATLESSLAPRAEATSAEDAHMAHHGPAMSFMSEAAQRSYRGLVYDTPRFAEYFFAATPIAEIAGLNIGSRPASRKKGQRIEDLRAIPWGFSWAQCRLMLTGWYGMGSAIEAYLETGAPGAPRSQRGRLAQLREMARDWPAFRTLLSNMEMVLAKSDLAIAARYAQLVPQRALREKIFGMISAEHARTLAMLKLLTRRELLADNPALQASLRERFAYIDPLNYLQVDLIRRHRAAQKSPAAEADERVQRAIHLTINGIAAGLRNSG
>NZ_CP053618.1|WP_006390049.1|1649032_1649746_-|7-cyano-7-deazaguanine-synthase-QueC
MLNHQRRALVLFSGGQDSTTCLAWALDRYAHVETVAFDYGQRHRIELDARLNVLRDIRARFPQWAPRLGEDHLLDLKVLGQVGDTAMTSDRAIEMQANGLPNTFVPGRNLLFLTLAAALGYRRQLDVLVGGMCETDFSGYPDCRDDTIKAQQVALGLGLGSRVTIETPLMWIDKSETWALARSLGGDALVETIVEESHTCYLGERGARHAWGYGCGECPACKLRRAGWDKWQAQGGA
>NZ_CP053618.1|WP_006390050.1|1647073_1648732_-|EAL-domain-containing-protein
MESGFTQGSIIMNRSRIILIFDNEFAKQGISDSLEQIGFVLNPVSLQEPAPACQAGEIQVHLCLPRDLDITIGQLRARFAHSTIIAIRHIESPAVRINALLAGADSCYGANISYSEVAAAIQSAQRKLTLCQPPAAVGPRRPDAPPDPTAAEKSWRLCDNEWTLVSPAGPGVSLTPMERAVLKGMHAHAERLIRRADFAVASLDIPGNGRALDLVISRLKRKGAAAGLSIPIRSLRGKGYSFSAALAQDSAAGDGREPAAPRKEGGPVSPLLAAIQGDRLQFHYQPIVAASDLEIVGAEALLRWRAAGGETLGIDGLLREAGAPEVAQALISWGIRTIASDQARWRQAARGCGPAVNINISPQSFARRDVVGVILRDIAVCGLAPRDIRIELTEEAALHAASADIRCMLEEFTSRGIQVWLDDFGKGYNNLEWLSTLPLAGLKLDKSIVWSAARQADAQKVLASICQLARDLDIVTVAEGVETEAHCRAAREAGCDLLQGFLFFRPGTADELATALNAQCQRRDDVAWARDRGAPATAVCDGGAPFSPVPGQ
>NZ_CP053618.1|WP_047992014.1|1645914_1647096_+|MFS-transporter
MIAARAVVCLGLTQLVGWGVTFYLIGALGPDMAADLGWNPATIYGGFSCAIVVMALVSPLAGRAVDRWGGHRIMPTGAVVAAAGCILLAAAHGPVAYFAAWTLLGLGMRLCLYDAAFASLARAAGPAARRPMSQITLFGGLASTVMWPVGHALSDWLGWRGAVLAYAALALATLPLYLALPRTRYAAPAQAPGQGGAGLARNARERRLAGALYATIAMLTNFLAAGNAAHLIPLLSGLGLAKALAVNVAALWGIGQFASRLADVALGSRLHPLTLTLAVAALLPLGFMLALLSGGHLAALAAYASLYGACNGLLTITRGTLPLALFDFRSYGAVTGALLMPSFLLTAAAPVAYAYVVQRHGAHAAMGMSAGVAGAILAAALALRWRFIARARG
>NZ_CP053618.1|WP_049053005.1|1645372_1645918_+|N-acetyltransferase
MPPSAAPILIRDSVDADLPAIKSIYAHHVQHGTASFELDPPSIQEMRQRRAGVLEKDMPYLVAEIDGEVVGYAYVTPYRPRPAYRHTVEDSVYVKAGRAGQGIGGRLLATLVERCTAAGWRQMLAVVGDSRNAASLAVHARQGFHPVGTLRSVGHKHGEWRDTVLMQRALGEGDGTPPQRP
>NZ_CP053618.1|WP_026382245.1|1644357_1645248_-|LysR-family-transcriptional-regulator
MRGLNLDALRTFAQVIELGSFSAAAERGGITQPAVSLQVRQLERRFGLKLVERVGRRAGPTAAGLELLTHIRAIDAALAQAEQAMTAHASQVTGRVRLGTGATACTYLLPPLLADLRRRFPALDVVASTGNTADMLRGLENNTLDIGLVTLPAPGRMIEATPVLEDEFVAIFPARGPLAIPDAVTPQALAALPLVLFEPGARTRRLVDDWFEEAGVAVKPVMELGSTEAMKEIVAAGLACAVLPRMAVSGAGQRGSLALRSLAPRLARTLAVVVRRDKPLSRGLRHLQEALLALRT
>NZ_CP053618.1|WP_006384641.1|1643372_1644410_+|2-isopropylmalate-synthase
MLDHPQHKYRPVQPFSRDYAERQWPTRRPSAPPIWMSTDMRDGNQALIEPMDAARKLRFFEQLVAVGLKEIEVAFPSASDTDFNFVRKLIEESRIPSDVTIEVLTQSRPDLIARTFESLRGAPRAIVHLYNPIAPQWRRIVFGMSRAEIKEIALAGTRQIRALADAHPETEWIYEYSPETFSLAELDFALEVCDAVSAIWRPSPARKMIINLPSTVECTTANVYADQIEWMHRRLARRDSIVLSVHPHNDRGTAVASAELAVLAGADRVEGCLFGNGERTGNVDLVTLALNLDRQGIASGLDFSDMAAVRDCVQACNQLPVDVFHPYAFTSAAPAMPPAGAAARG
>NZ_CP053618.1|WP_053499537.1|1642101_1642929_-|helix-turn-helix-transcriptional-regulator
MDKPKPPSRLAGSRKPADLDLFPYESSLRPVAALAVDYEDGHRVGRHRHRRSQLVYAISGVMVVDTDAGIWVVPPTRGVWVPAWVSHSIRMSGEPRMRTVFVEPGAASHLPTECCVLSISPLLRELMVAAAEVPLDWKPGTRDGRLMLLLLDELKQEPVLPLHLPQPSEPRLARICRAIVRHPERQAGAADWARELGVDPKTVHRLFLRHTGMTFGRWRQQARLLAAMERLARGERVLDVALDLGYESPSAFAAMFRKALGEPPSAFAARGAASA
>NZ_CP053618.1|WP_006390042.1|1655791_1656520_+|SDR-family-oxidoreductase
MSKPTAYLVTGGSAGIGAAIVRMLLDAGHKVVNIDYRLPEHPPTGLVSYQADLTDEARTKEVAAEVTAAYDIVGLVNNAGATRPGTADTATLADLDYVVNLHLRTALILVQAALPAMRAAGFGRIVNMSSRAALGKPDRVVYSATKAGLVGLTRTLAMELGGDGITVNAIGPGPIATDLFTKSNPAGAPQTERIINSIVVKRLGTPEDVARAAMFFLSPDNGFVTGQMLYVCGGTTLGVAPI
>NZ_CP053618.1|WP_020926101.1|1656570_1657353_-|IclR-family-transcriptional-regulator
MAEQATQQPSDSYVQSFARGLSVIRAFGPDRSQMTLSEVAAVTGLTRAGARRILLTLEHLGYVTVEDRKFALTPRILELGYAYLSGTPLWNLALPYMEEVAEQTRESCSVSVLEGADIVYILRLSTHKVMTINLAVGSRLPAWVTSMGRVLLAGLPAAELDRVLAMSQIQAYTKDTVTDIGALKAILAGVRADGYACVAQELEPGLQSVAVPIVDRSGRVIAAMNVSGHANRFSREEMLATFLPPLRHAADQINHALLRR
>NZ_CP053618.1|WP_024070578.1|1657523_1658213_+|3-oxoacid-CoA-transferase-subunit-A
MISKLVASAAAALADVPDGATVMIGGFGTAGQPMELIDALLEQGAKDLVIINNNAGNGTTGLAALLGANRVRKIICSFPRQVDSQIFDGLYRSGKIELELVPQGNLAERIRAAGAGIGAFFSPTGYGTPLADGKETREINGRQYVLEYPLHADYALIKAERGDRWGNLVYRKTARNFGPIMASAARVAVAQVREVVELGALDPETVVTPGIFVQRVVQIDAAQAAKEQQ
>NZ_CP053618.1|WP_020926099.1|1658209_1658854_+|CoA-transferase-subunit-B
MSTKLTRDQIAARVAQDIPEGAYVNLGIGLPTLVANHLPADREVILHTENGMLGMGPAPAKGEEDYDLINAGKQPVTELPGCSFFHHADSFAMMRGGHLDICVLGAFQVSQHGDLANWHTGAPDAIPAVGGAMDLAIGAKDVFVMMELQTREGQSKLVDACTYPLTGVRCVSRVYTDVAVFDIRADGVTVIDMFGETTADELLRLTGLPLKFSN
>NZ_CP053618.1|WP_020926098.1|1658906_1659182_+|muconolactone-Delta-isomerase
MLFMVQMQVNLPVDMPAAQADKLKADEKALAQQLQRDGKWKSLWRVVGRYANVSIFDVQDNDELHALLSSLPLFPYMDIQVTALARHPSAI
>NZ_CP053618.1|WP_024070579.1|1659194_1659491_+|YciI-family-protein
MPYIIETFDKPDHQAVRQQHRAAHLEYLDANKHLLLACGAKLQDDGKDLGGGLYIVDLDTREAAQQFIDADPFAQAQLFQRVTITRWRKAYVDGTCHL
>NZ_CP053618.1|WP_155867591.1|1659546_1660326_+|3-oxoadipate-enol-lactonase
MSYADLSQARLFYVIDGPADAPVLVLSNSLGTNADMWARQVPALSKHFRVLRYDTRGHGKSSIPDGEYSFAQLGNDVAELLAHLNIERAHFCGLSMGGPTGLWLALNRPELIGKLILCNTAARIGSAEGWSARIAAVAEQTLEKMAPTLVERWLTDGYRAAEPGLSQVLVDMLRRTSDAGYSGNCAALRDADFREQVSAITAPTLVISSTHDLAATPAQGQELAAAINGARYLELNTSHISNWEQPEAFTRAVVDFLTE
>NZ_CP053618.1|WP_024070581.1|1660329_1661370_+|cyclase-family-protein
MQRWTHRPEGSNWGDFGPDDQLGRLNLITEEQVLKGAREIRAGKTFCLSLPLDLPGGNVLNPRRHPPQLSPTRLADTPYLNFPLRNVNPDAVDVLSDDQVLLSMQYSTQWDALAHVGALFDADGDGQPELRYYNGFQAGVDVIGPADGDHTGCGCNSGGPSAALKLGVENLAQKGMQGRGVLLDLARHYGPGRTLVGHAEIMHVLKTDGIEIEPGDMLVLRTGYAEAVVAMAGKPDAEVLHTYGAALDGTDAALLQWITDSGIAAICADNYAVEAYPAREKTGPRAMLPLHHHCLFKLGLPLAELWYLKDLADWLRANGRHRFMLTAPPLRLPHAIGSPVTPIATV
>NZ_CP053618.1|WP_024070582.1|1661550_1661919_-|phosphate-starvation-inducible-protein-precursor
MLSRTSQLASAIVLSACFLGAVHAQTPAATPAPAKTPAPAATPAKTPTAQQQRMADCNKSAEGKKGDDRKTYMSACLKGEAPPPAKQLTPQQQKMKDCNAKAGEQKLTGDKRKTFMSTCLKG
>NZ_CP053618.1|WP_006390029.1|1662297_1662633_+|hypothetical-protein
MKTVLASLALLAGLTGAAHAQNLYGVTLGNIQAIRDANENVSTITGSLANQSARAVNYVMLTFVLYDEQGREIGRVRDDDIGPLAPGQIKMIRAITPLQFAKVTALDIRAR

Crispr_ID: NZ_CP053618_3

• CRISPR_ID: NZ_CP053618_3
• CRISPR_location: 1882868-1882975
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_3

Consensus_repeat	Method
GAAGGCGGCTTCCGTGGCGGCGACCGC	CRISPRCasFinder

spacers of NZ_CP053618_3

>3.1|1882895|54|NZ_CP053618|CRISPRCasFinder
GATTCGCGTCCGAGCTTCAGCGATCGCCCCAGCTTTGGCGACCGTCCACAGCGC

CRISPR arrays and Neighbor proteins around NZ_CP053618_3

CRISPR arrays

The CRISPR arrays of NZ_CP053618_3

>merge|NZ_CP053618|3|1882868-1882975|CRISPRCasFinder
GAAGGCGGCTTCCGTGGCGGCGACCGCGATTCGCGTCCGAGCTTCAGCGATCGCCCCAGCTTTGGCGACCGTCCACAGCGCGAAGGCGGCTTCCGCGGCGGCGACCGC

>NZ_CP053618|3|3|1882868-1882975|CRISPRCasFinder
GAAGGCGGCTTCCGTGGCGGCGACCGC	GATTCGCGTCCGAGCTTCAGCGATCGCCCCAGCTTTGGCGACCGTCCACAGCGC
GAAGGCGGCTTCCGCGGCGGCGACCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_173010591.1|1880255_1881017_+|uracil-DNA-glycosylase	unknown	unknown	gnl|CDD|235376
NZ_CP053618.1|WP_020925929.1|1894353_1895196_-|methylenetetrahydrofolate-reductase-[NAD(P)H]	unknown	unknown	gnl|CDD|273212
NZ_CP053618.1|WP_161801354.1|1885453_1887532_-|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl|CDD|381604
NZ_CP053618.1|WP_159070199.1|1866194_1867142_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_173010593.1|1888878_1890309_+|circularly-permuted-type-2-ATP-grasp-protein	unknown	unknown	gnl|CDD|225190
NZ_CP053618.1|WP_053499022.1|1884353_1885457_-|tRNA-CCA-pyrophosphorylase	unknown	unknown	gnl|CDD|139469
NZ_CP053618.1|WP_060720932.1|1883159_1884341_+|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|224481
NZ_CP053618.1|WP_080564321.1|1864045_1864249_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_108914025.1|1864614_1864875_-|hypothetical-protein	unknown	unknown	gnl|CDD|373059
NZ_CP053618.1|WP_173010590.1|1878230_1879982_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl|CDD|225387
NZ_CP053618.1|WP_024070704.1|1891311_1892115_+|transglutaminase-family-protein	unknown	unknown	gnl|CDD|224224
NZ_CP053618.1|WP_131727705.1|1869495_1869882_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_173010589.1|1868497_1868941_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_053499028.1|1893187_1894186_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270294
NZ_CP053618.1|WP_173010588.1|1865486_1866143_-|hypothetical-protein	unknown	unknown	gnl|CDD|223971
NZ_CP053618.1|WP_173010592.1|1887799_1888474_+|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl|CDD|274270
NZ_CP053618.1|WP_049055700.1|1890311_1891298_+|alpha-E-domain-containing-protein	unknown	unknown	gnl|CDD|377234
NZ_CP053618.1|WP_131727064.1|1864938_1865490_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_053497532.1|1862990_1863338_-|CZB-domain-containing-protein	unknown	unknown	gnl|CDD|379331
NZ_CP053618.1|WP_026382086.1|1892170_1893034_+|proteasome-type-protease	unknown	unknown	gnl|CDD|239734

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_173010591.1|1880255_1881017_+|uracil-DNA-glycosylase	gnl|CDD|235376	PRK05254, PRK05254, uracil-DNA glycosylase; Provisional.	3.59721e-113
NZ_CP053618.1|WP_020925929.1|1894353_1895196_-|methylenetetrahydrofolate-reductase-[NAD(P)H]	gnl|CDD|273212	TIGR00676, 510-methylenetetrahydrofolate_reductase., 5,10-methylenetetrahydrofolate reductase, prokaryotic form. The enzyme activities methylenetetrahydrofolate reductase (EC 1.5.1.20) and 5,10-methylenetetrahydrofolate reductase (FADH) (EC 1.7.99.5) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynthesis, Aspartate family].	4.4577e-134
NZ_CP053618.1|WP_161801354.1|1885453_1887532_-|transglycosylase-SLT-domain-containing-protein	gnl|CDD|381604	cd13401, Slt70-like, 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.	1.55507e-60
NZ_CP053618.1|WP_173010593.1|1888878_1890309_+|circularly-permuted-type-2-ATP-grasp-protein	gnl|CDD|225190	COG2308, COG2308, Uncharacterized conserved protein [Function unknown].	0
NZ_CP053618.1|WP_053499022.1|1884353_1885457_-|tRNA-CCA-pyrophosphorylase	gnl|CDD|139469	PRK13297, PRK13297, tRNA CCA-pyrophosphorylase; Provisional.	1.89132e-180
NZ_CP053618.1|WP_060720932.1|1883159_1884341_+|SAM-dependent-methyltransferase	gnl|CDD|224481	COG1565, COG1565, Uncharacterized conserved protein [Function unknown].	5.19934e-105
NZ_CP053618.1|WP_024070704.1|1891311_1892115_+|transglutaminase-family-protein	gnl|CDD|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	2.13904e-42
NZ_CP053618.1|WP_108914025.1|1864614_1864875_-|hypothetical-protein	gnl|CDD|373059	pfam14424, Toxin-deaminase, The BURPS668_1122 family of deaminases. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Burkholderia BURPS668_1122. Members of this family are found as toxins in polymorphic toxin systems in a wide range of bacteria and in the eukaryote Perkinsus. Members of this family typically possess a DxE catalytic motif in Helix-2 of the core fold instead of the more common C[H]xE motif. The Perkinsus versions are predicted to be inactive.	2.85968e-11
NZ_CP053618.1|WP_173010590.1|1878230_1879982_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl|CDD|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	4.20266e-128
NZ_CP053618.1|WP_053499028.1|1893187_1894186_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270294	cd13576, PBP2_BugD_Asp, Aspartic acid transporter of Bug (Bordetella uptake gene) protein family; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) receptors present in a number of bacterial species, but mainly in proteobacteria. Bug proteins are the PBP components of the tripartite carboxylate transporters (TTT). Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	3.45735e-131
NZ_CP053618.1|WP_173010588.1|1865486_1866143_-|hypothetical-protein	gnl|CDD|223971	COG1041, COG1041, Predicted DNA modification methylase [DNA replication, recombination, and repair].	0.00254696
NZ_CP053618.1|WP_173010592.1|1887799_1888474_+|5-formyltetrahydrofolate-cyclo-ligase	gnl|CDD|274270	TIGR02727, Uncharacterized_protein_YqgN, 5,10-methenyltetrahydrofolate synthetase. This enzyme, 5,10-methenyltetrahydrofolate synthetase, is also called 5-formyltetrahydrofolate cycloligase. Function of bacterial proteins in this family was inferred originally from the known activity of eukaryotic homologs. Recently, activity was shown explicitly for the member from Mycoplasma pneumonia. Members of this family from alpha- and gamma-proteobacteria, designated ygfA, are often found in an operon with 6S structural RNA, and show a similar pattern of high expression during stationary phase. The function may be to deplete folate to slow 1-carbon biosynthetic metabolism. [Central intermediary metabolism, One-carbon metabolism].	4.17272e-42
NZ_CP053618.1|WP_049055700.1|1890311_1891298_+|alpha-E-domain-containing-protein	gnl|CDD|377234	pfam04168, Alpha-E, A predicted alpha-helical domain with a conserved ER motif. An uncharacterized alpha helical domain containing a highly conserved ER motif and typically found as a tandem duplication. Contextual analysis suggests that it functions in a distinct peptide synthesis/modification system comprising of a transglutaminase, a peptidase of the NTN-hydrolase superfamily, an active and inactive circularly permuted ATP-grasp domains and a transglutaminase fused N-terminal to a circularly permuted COOH-NH2 ligase domain.	2.31021e-115
NZ_CP053618.1|WP_053497532.1|1862990_1863338_-|CZB-domain-containing-protein	gnl|CDD|379331	pfam13682, CZB, Chemoreceptor zinc-binding domain. The chemoreceptor zinc-binding domain (CZB) is found in bacterial signal transduction proteins - most frequently receptors involved in chemotaxis and motility, but also in c-di-GMP signalling and nitrate/nitrite-sensing. Originally discovered in the cytoplasmic chemoreceptor TlpD from Helicobacter pylori, it is often found C-terminal to the MCPsignal domain in cytoplasmic chemoreceptor proteins. The CZB domain contains a core sequence motif, Hxx[WFYL]x21-28Cx[LFMVI]Gx[WFLVI]x18-27HxxxH. The highly-conserved H-C-H-H residues of this motif are believed to coordinate zinc; mutating the latter two histidines of the motif to alanines abolishes Zn binding. This domain binds zinc with high affinity, with a Kd in the femtomolar range. This domain has been shown in E. coli to be a zinc sensor that regulates the catalytic activity of pfam00990.	2.75811e-10
NZ_CP053618.1|WP_026382086.1|1892170_1893034_+|proteasome-type-protease	gnl|CDD|239734	cd03765, proteasome_beta_bacterial, Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming an elongated alpha-beta-beta-alpha cylinder with a central cavity. The proteasome alpha and beta subunits are members of the N-terminal nucleophile (Ntn)-hydrolase superfamily. Their N-terminal threonine residues are exposed as a nucleophile in peptide bond hydrolysis. Mammals have 7 alpha and 7 beta proteasome subunits while archaea have one of each.	1.2826e-136

Protein sequences

>NZ_CP053618.1|WP_173010591.1|1880255_1881017_+|uracil-DNA-glycosylase
MPIDNRLIPSALAAQTAQLPAAWQAALQAPRVATALQAVTDHVEKRLAEGAVIYPATPFRALHGLAPSDVRVVILGQDPYHGPGQAQGLAFSVPDDCKRPPSLRNIFNEIAQEYPGTPLPAGNDLTPWAAQGVLLLNTALTVEDGQPASHAKRGWETVTDALIALVAQDRSPKVFMLWGAHAQAKQALLPHDSGHLVLMANHPSPLSARRPPVPFLGCGHFLATNRWLSDQGKNPIDWKLDKKIIPAQGEFGL
>NZ_CP053618.1|WP_173010590.1|1878230_1879982_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MHTVFMRRRLRQRRLPSLALSISFVAIFAILPPAAAQLSPAEAAARASDIQRRQEQELDAQRARAAERPDVLSAPAAPAAADGVLVLPTESPCFTVAKVAWDGPAPSATMRRASEGVLGQCVGGQGLQALQAHLMARLIDRGLITARVLVPEQSLASGTLTLRYVPGRIAGVKSDGAPGWWRTALPTWPGGEVNQRDLDQALENIRRLAGQADASIDVAPGPELGDSDIIIKPGTGKRWHAYVGGDNAGMESTGKNQVNAGLTLDSPLFLYDQLSVSWNSNADLRNNDAGSRAASINYSIPFGYWTLFAGASKSRYRQTVAGFEEPIVYGGTSKQIEAGVSVVPYRGASYKGTAMLKFLRKRANSTLNDIDIEVQRRDVVGYEFSYGHRQYIDQMVLDLGGGVRGTLPQFSDQPGYVYGDPDWNGRSTILTANAGLYLPFKVAGQQLAYQANWQIQHAKTPIVPADYFTIGNRYAVRGFDGQMTLAAEDGWTLRNDLSLNLGNLGQQLYTGLDAGRVGGPSAEYLASRTLVGAVAGLRGRIAIPGAANAVNASYDLSAGWPLKKPDNLKTQSTVFAATLMFEF
>NZ_CP053618.1|WP_131727705.1|1869495_1869882_-|hypothetical-protein
MDIEFFRPIRISLDVVETDERLPSVKFKFEVESNAFSESFLYRGEVWIACKDFDIFNYSLGRTSCHLTSLDGLFSLEIVQGSGRYVLRWFRRKESVFGAVAEMKYESSLDSDDISAIKSSFDSFAKWW
>NZ_CP053618.1|WP_173010589.1|1868497_1868941_-|hypothetical-protein
MISNEISAREGIILNFIEKMGPLAWRKYQQRYPHVWVKDHSEIEDRSSFPPYISFRFQKEQAGVIATLRNLISTYGELRWVLEPHFRENLPGTNWLIAPGDVIAMRPALKNNSITVYEFFAKEYPLFGPVAYLDLDGLVMHFKKNIK
>NZ_CP053618.1|WP_159070199.1|1866194_1867142_-|hypothetical-protein
MNTLKPIFDKKKIEAGFEIASAASRQVGQFLTNRAKEAKALEDALKNESEGPRRDQLRQALEDAKTWGPGGESRRWLTAILGAVSGNVTGATGDAIQAVAVNYLQGLAASQVKEIVSALGDGPQAEAARAAMHAIVGCAGAAGKGSDCSAGALGAGSGAVINALLSGDASKMTPEEKEVRRNLVGSLVAGIAQASGVSGAEAVFAATNETENNYLKPDELKSYLAALQAWKECSGDVCAQAKKEVRRLQAISTERNYAADSACLENPGACAAAAQELRADITALEVQANSLDRTEAATAANNLLQARKQYYSNLE
>NZ_CP053618.1|WP_173010588.1|1865486_1866143_-|hypothetical-protein
MASMSGQELYESGHLTQQEAQDLQAMRRETFAAAFVPPALAAGVKGGGSAAGRRIQSVAEEAKASALGGAKATGGKPTVELFGGKNAQTPGAINVDIRADIQSGIRADATKLPFKDGSLGEVIATNPYMGPGGKMMSFLPEATRVVEPGGKIYINANAANPYGKLPSQAELDSLGLRVVQNNGGLDSRFAGQTFMQSDGVTPVKDVSSMRTIILERIK
>NZ_CP053618.1|WP_131727064.1|1864938_1865490_-|hypothetical-protein
MRLDTDFGSLDVYMSVYGAHVFSGNVLKVYLKDGLGVSSGLRDIFPRKYFYDPWNGNKYSETRKVDGLLVGRLENSGEWVGYEDKTISAEVLKYEYVGNCWFVFEGVSFSLRKIGKYIEGGKEPGGGELIENFDLPKTTVSNIKEYFLEGVLDVPPGPGWMFWEIHAESFYLEIPDRPAPLGA
>NZ_CP053618.1|WP_108914025.1|1864614_1864875_-|hypothetical-protein
MAQRVMGVRVGLPSNLRRSGNVVIAEIDIPRIPRQMAAHSQIFDAGKGLIGSGSGNFVAQSVPNKAGDMVYRGIDTEYKILDNIAD
>NZ_CP053618.1|WP_080564321.1|1864045_1864249_-|hypothetical-protein
MSIVRRGVVVSGEYSGWKILVADDRDGDTGGYYLYLKRSDTEGFDCWFEREAELQTQLADFEVKWIG
>NZ_CP053618.1|WP_053497532.1|1862990_1863338_-|CZB-domain-containing-protein
MNLDESIQKHAEWKLKFRSAISRKEQMDAETIGKDNCCQLGVWLYGEGKLKYSAKPEFGAIVQKHKAFHTEAGKIARLINSNQYEQAEKEMGTGTPYSQASSAVGAAIIAFKRHL
>NZ_CP053618.1|WP_060720932.1|1883159_1884341_+|SAM-dependent-methyltransferase
MQRPAPANLPPLSPAAQAHSEAAAAHLRAAIAAASGWLPFDHWMAEALYAPGLGYYAAGNVKLAEADARAPAGDFVTAPQLTPLFARTLARQVAQVLRQTDTQTVLEFGAGTGALAEGVLRELDAQGLQDTQYLILEVSADLRARQAERLAPFGERVRWLDALPERFRGCVLANEVLDAMPVSLFRWSDDGVVLERGVTLDPAQGFVWEDRPAPRRLAEAVAARMPALPGYVSEINLQAEAWIDGMSGWLEQGAALLVDYGFPQGEYYHPQRAGGTLMCHLRHHAHGDPFTAPGLQDITAHVDFTAMADAAQAAGLQVLGYTSQARFLMNSGLMELLAQLDPTDARTYAQAVAPVQKLLSEAEMGELFKVLAVGRGITQPLIGFARGDRLGKL
>NZ_CP053618.1|WP_053499022.1|1884353_1885457_-|tRNA-CCA-pyrophosphorylase
MTADVATQGLQAYIVGGAVRDALLGLTPGDHDWVVVGATPEDMARRGFIPVGGDFPVFLHPVTKEEYALARTERKSGRGYKGFTFYTGTDVTLEEDLRRRDLTVNAIAQKQDGELVDPLGGAADVQARVFRHVGEAFQEDPVRILRLARFAARFADFSVAPETMALCRQMVEAGEADALVPERVWKEVSRGLMAAAPSRMLDVLRQSGALERVMPELTGSEETGGDVDRAAARKLSLPGRYALLCRLSPGREALGRRLRVPTECNDYARLLPDMLTGLDAAQAAGADPADAQLALMERVDALRKPERFLDLLAAAAVLRPVDGNAWRDRAEAVRGVDAGAIARSCAGDPARIKQSLREARLQRLRAA
>NZ_CP053618.1|WP_161801354.1|1885453_1887532_-|transglycosylase-SLT-domain-containing-protein
MKSPRTADARAGLRRWLPLLALFTAACAPVDAQQRTASVNTQPQPAAQAPQPAIAVPPAVLAGLPPTAETPALAAVVAAREAMNRKQWSILGALVPQAKSDPLGMYPEYWLLRYQLWSPPAGGRPNAELQKFINGNGDAYLADRLRADWLLAAARSGDFETVRKLAPVKNSNAQVECAILNAKHMTGQRATAAQAMAVFAPGSACWTLYDQLVADNVLGWDQLEPQLRDAIEANKTTDARKFVQYMFEPRDQKTYDVLIKDPMRWLTRQDRLPVGRNEKELVTIALARLARSDINVADSYLRREWAKSMAKSNLAWIRGQYALVAALNLDSRADDWYHEAGHIRMTEYNAGWKVRAALRQPKIDWKWVIESIDQMPAAQQQDPSWIYWKARGMAATGRREQANAAYASIADRFDFYGQLAAEELGRRITVPPRPAPISDSEIAEARANPGLRRAVQLFRLGWRQEAVPEWNFALRGMSDRQLLAAAELARAENIYDRVVNTSDRTEKEFDFSQRFIAPFEGRVTAKANAIALDPAWVYGLIRQESRFIMDARSHVGASGLMQLMPATAKWVAGKIGMSNFTPDSVNDFDTNTELGTNYLNMVLRDLNGSQMLASAGYNAGPRRPHNWRSTFNHPVEGAIFAETIPFNETRTYVKNVMSNSVYYAAMFSGQPQSLKERLGNVVPLGAESTTLP
>NZ_CP053618.1|WP_173010592.1|1887799_1888474_+|5-formyltetrahydrofolate-cyclo-ligase
MTTQNTPEDTASQLRTRLRKLRAELPEDQRSRGGLLMRARLFTWLNVARDEAVRAGRRAPAVVAAFWPMEDEPDLRPLLEQWTENGVTVALPVVRERNAPLAFLPWTPDAELRAGPYGIQEPARGAEVLPDVLLVPTLGYTESADRLGYGGGYYDRTLAALRERGHAFTTIGVAWSCGELDPGYEPAAHDFRLDAVITPDGWVPHAPQDQPGQGGTTVQRYTLR
>NZ_CP053618.1|WP_173010593.1|1888878_1890309_+|circularly-permuted-type-2-ATP-grasp-protein
MKDRSSRPAAYDEMRDSAGGIRSHYQAFERWHQEQSAEAMAARRLEADLSFRRVGITFSVAGDAAGTERLIPFDMIPRIIPADEWRRLEAGLKQRVRALNMFIHDIYHGHEIVRAGVVPAEQVFLNAQYRPEMQDVDVAEDIYCHIAGVDIVRAGAGEFYVLEDNLRVPSGVSYMLENRKMSMRLMPDAFSRIKVEPVAHYPDLLLDNLREVAPHGGDDPTVVVLTPGMYNSAYFEHAFLAQQMGVELVEGQDLFVEQNTVYMRTTQGPRKVDVIYRRLDDDFLDPLSFRPDSALGVPGLLSVYRAGRVTLANAIGTGIADDKSTYLYVPDMIRFYLGEEPILSNVPTWRCGRPDELSHVLANMHDLVVKEVHGAGGYGMLVGPSASRAEVESFKERVRANPANYIAQPTLALSTVPTYVESGVAPRHVDLRPYVLCGKDIRTVPGGLCRVALTEGSLVVNSSQGGGTKDTWVLEE
>NZ_CP053618.1|WP_049055700.1|1890311_1891298_+|alpha-E-domain-containing-protein
MLSRTADNLFWMCRYTERAENTARMLDVNLQMSLLPQDAQTREGSWNAVLRISELHRLYHAKHAAISPQDVLQYMVRDAENPSSIYSCMRAARENARAVRGSLTTEVWETYNTTWLELLKHLHTGLLERNPGEFFEWVKFRSHLARGVTIGTMLEDEALYFLRIGMHLERADNTARMLDVKFHERDGDGAPQQQQEGRGEGSPSGALQSEFYRWSALLSSVSGLEIYRKVYRDVITPDRVAELLILHPDMPRSLLAAMRAVSEDLARVSNQRSTETQRRAGMLCAELQFGRVEDILRSGLHQYLEHFLDRINDLGNRISQDFLVPLSA
>NZ_CP053618.1|WP_024070704.1|1891311_1892115_+|transglutaminase-family-protein
MKQIITHVTHYRYTAPVTYSIQTLRLTPRDDEHQRVLRWHIEAPGALEQQVDAYGNITHTLTLNRPHTEIELRVVGQVLVGSLTQGALGGEDSRLPVHAYCVQTPLTQADDTILAFAHAVLPDGLNTPADVLTLATAIHDRVAYEPGTTDVTTAAGQVLALGHGVCQDHAHLFLACVRGLGVPARYVSGYLYTTAQHAASHAWADVWLAGAGWTSVDVTNRQFASDCHCRLAVGRDYDSASPVRGVRSGGGEESMEVNVQVQTAAQQ
>NZ_CP053618.1|WP_026382086.1|1892170_1893034_+|proteasome-type-protease
MTYCVAARLDAGLVFLSDSRTNAGVDQISVFRKMTVFERPGERMMVLMTSGNLAVSQAVLNALARQHDEGGETVWNAPDMFEATRRVGAAVRAVYHREAAALHEQGVDFNVSLIFGGQIGSERCRLFQVYSAGNFIEAGSECPYFQIGEAKYGKPILDRVLRPDTSLDEAAKCALISMDSTLRSNISVGLPLDLLVYDADALRVTHFASIDEHNEYFRMIRGTWGERLRQVFAEIPDPLWTRPEDPGSLVPASRIHQPLRAEPVDMTPPAYPTPQVLAQDPGKDQPN
>NZ_CP053618.1|WP_053499028.1|1893187_1894186_+|ABC-transporter-substrate-binding-protein
MTPYFPRPLRRLAAPLLALGCLAGGSAAAQGGYPNHPISLVVPFAAGGPTDVVARSLGAAMSKTLGQSIVVENRPGAGGTLAATHVARAAPDGYTFLIHHNGMATAPALYRKLPFNPLTDFAYVGQVADVPMTLLGRKDLPPGDMVEFIKYARANGNKINLANAGLGAVSQLCGMLLQEALGTQFTTIPYAGTAPALTALLGGQVDVLCDQTTQTIPHIKAQRVKLYGVTTLDRIRTLPDSPTLQESGVKGFEVKVWHGVYAPKGTPPEVVAKFNESLRAALKDPAFTQKMAELGAEIVPEAKQTPAGLQSWLQSEVDKWGPIIRKAGVYAD
>NZ_CP053618.1|WP_020925929.1|1894353_1895196_-|methylenetetrahydrofolate-reductase-[NAD(P)H]
MSDSTSPAFSLEFFPPRDLAGQERLVRAAKQMLAIQPKYVSVTFGAGGSTRAGTADAVRTLRNLGCDAAPHLSCVGASRQDLRDILQAYKNEGVRRVVALRGDLPSGMGGDAGELRYANELVSFIREETGDWFHIEVAAYPEMHPQAANPSADLDHFVAKVKAGANAAITQYFFNADAYFDFVDRAQAKGVRVPIVPGIMPITNHTQLLRFSEMCGAEVPRWIRLRLAELGDDKASIRAFGVDVVTELCQNLLDNGAPGLHFYTLNHAEAPLAVWKELSV

Crispr_ID: NZ_CP053618_4

• CRISPR_ID: NZ_CP053618_4
• CRISPR_location: 2533297-2533431
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_4

Consensus_repeat	Method
GGGGGGCAGCTAGCGCGCGAAGCGCGCGCGGCGTGGGGGTCCTT	CRISPRCasFinder

spacers of NZ_CP053618_4

>4.1|2533341|47|NZ_CP053618|CRISPRCasFinder
TCCTACCGCCCGCCCGCCGGGCCGCCCCAAGGGCGGGCAGCCCCATT

CRISPR arrays and Neighbor proteins around NZ_CP053618_4

CRISPR arrays

The CRISPR arrays of NZ_CP053618_4

>merge|NZ_CP053618|4|2533297-2533431|CRISPRCasFinder
GGGGGGCAGCTAGCGCGCGAAGCGCGCGCGGCGTGGGGGTCCTTTCCTACCGCCCGCCCGCCGGGCCGCCCCAAGGGCGGGCAGCCCCATTGGGGGGCAGCTAGCGCGCGAAGCGCGCGCGGCGTGGGGGCTCCT

>NZ_CP053618|4|4|2533297-2533431|CRISPRCasFinder
GGGGGGCAGCTAGCGCGCGAAGCGCGCGCGGCGTGGGGGTCCTT	TCCTACCGCCCGCCCGCCGGGCCGCCCCAAGGGCGGGCAGCCCCATT
GGGGGGCAGCTAGCGCGCGAAGCGCGCGCGGCGTGGGGGCTCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_006387324.1|2539795_2540443_+|formate-dehydrogenase-subunit-gamma	unknown	unknown	gnl|CDD|182608
NZ_CP053618.1|WP_054499510.1|2534005_2535553_-|DUF1254-domain-containing-protein	unknown	unknown	gnl|CDD|227659
NZ_CP053618.1|WP_054485780.1|2529331_2530207_+|DUF2950-family-protein	unknown	unknown	gnl|CDD|371539
NZ_CP053618.1|WP_024067520.1|2546797_2547901_-|transglutaminase-domain-containing-protein	unknown	unknown	gnl|CDD|376628
NZ_CP053618.1|WP_006387309.1|2524326_2525136_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|236863
NZ_CP053618.1|WP_173010693.1|2541507_2542941_+|L-seryl-tRNA(Sec)-selenium-transferase	unknown	unknown	gnl|CDD|235278
NZ_CP053618.1|WP_054443741.1|2545188_2546223_+|glycosyltransferase	unknown	unknown	gnl|CDD|182223
NZ_CP053618.1|WP_006387318.1|2532142_2533156_+|sterol-desaturase-family-protein	unknown	unknown	gnl|CDD|225546
NZ_CP053618.1|WP_173010694.1|2542937_2544875_+|selenocysteine-specific-translation-elongation-factor	unknown	unknown	gnl|CDD|182508
NZ_CP053618.1|WP_047993090.1|2528006_2529308_+|DUF3300-domain-containing-protein	unknown	unknown	gnl|CDD|378701
NZ_CP053618.1|WP_020925491.1|2531345_2532140_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|213022
NZ_CP053618.1|WP_006387311.1|2525814_2526648_+|hypothetical-protein	unknown	unknown	gnl|CDD|270317
NZ_CP053618.1|WP_006387310.1|2525135_2525798_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224922
NZ_CP053618.1|WP_053499990.1|2526673_2527579_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|183055
NZ_CP053618.1|WP_020925488.1|2538903_2539803_+|formate-dehydrogenase-subunit-beta	unknown	unknown	gnl|CDD|273705
NZ_CP053618.1|WP_049051928.1|2546240_2546783_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_CP053618.1|WP_006227327.1|2527670_2527886_+|TOBE-domain-containing-protein	unknown	unknown	gnl|CDD|226113
NZ_CP053618.1|WP_035182973.1|2540569_2541505_+|formate-dehydrogenase-accessory-protein-FdhE	unknown	unknown	gnl|CDD|377247
NZ_CP053618.1|WP_157140507.1|2535824_2538893_+|formate-dehydrogenase-N-subunit-alpha	unknown	unknown	gnl|CDD|273689
NZ_CP053618.1|WP_047993088.1|2530417_2531362_+|hypothetical-protein	unknown	unknown	gnl|CDD|274824

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_006387324.1|2539795_2540443_+|formate-dehydrogenase-subunit-gamma	gnl|CDD|182608	PRK10639, PRK10639, formate dehydrogenase cytochrome b556 subunit.	7.11743e-73
NZ_CP053618.1|WP_054499510.1|2534005_2535553_-|DUF1254-domain-containing-protein	gnl|CDD|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	6.71687e-71
NZ_CP053618.1|WP_054485780.1|2529331_2530207_+|DUF2950-family-protein	gnl|CDD|371539	pfam11453, DUF2950, Protein of unknown function (DUF2950). This is a bacterial family of uncharacterized proteins.	2.1994e-89
NZ_CP053618.1|WP_024067520.1|2546797_2547901_-|transglutaminase-domain-containing-protein	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	1.85559e-23
NZ_CP053618.1|WP_006387309.1|2524326_2525136_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|236863	PRK11153, metN, DL-methionine transporter ATP-binding subunit; Provisional.	4.20493e-127
NZ_CP053618.1|WP_173010693.1|2541507_2542941_+|L-seryl-tRNA(Sec)-selenium-transferase	gnl|CDD|235278	PRK04311, PRK04311, selenocysteine synthase; Provisional.	0
NZ_CP053618.1|WP_054443741.1|2545188_2546223_+|glycosyltransferase	gnl|CDD|182223	PRK10073, PRK10073, putative glycosyl transferase; Provisional.	2.57584e-52
NZ_CP053618.1|WP_006387318.1|2532142_2533156_+|sterol-desaturase-family-protein	gnl|CDD|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	6.12579e-30
NZ_CP053618.1|WP_173010694.1|2542937_2544875_+|selenocysteine-specific-translation-elongation-factor	gnl|CDD|182508	PRK10512, PRK10512, selenocysteinyl-tRNA-specific translation factor; Provisional.	0
NZ_CP053618.1|WP_047993090.1|2528006_2529308_+|DUF3300-domain-containing-protein	gnl|CDD|378701	pfam11737, DUF3300, Protein of unknown function (DUF3300). This hypothetical bacterial gene product has a long hydrophobic segment and is thus likely to be a membrane protein.	1.32336e-123
NZ_CP053618.1|WP_020925491.1|2531345_2532140_+|polysaccharide-deacetylase-family-protein	gnl|CDD|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	1.79926e-32
NZ_CP053618.1|WP_006387311.1|2525814_2526648_+|hypothetical-protein	gnl|CDD|270317	cd13599, PBP2_lipoprotein_Gna1946, The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold. Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	1.19026e-107
NZ_CP053618.1|WP_006387310.1|2525135_2525798_+|ABC-transporter-permease	gnl|CDD|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	3.22229e-91
NZ_CP053618.1|WP_053499990.1|2526673_2527579_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|183055	PRK11247, ssuB, aliphatic sulfonates transport ATP-binding subunit; Provisional.	1.65901e-112
NZ_CP053618.1|WP_020925488.1|2538903_2539803_+|formate-dehydrogenase-subunit-beta	gnl|CDD|273705	TIGR01582, Formate_dehydrogenase_iron-sulfur_subunit, formate dehydrogenase, beta subunit, Fe-S containing. This model represents the beta subunit of the gamma-proteobacterial formate dehydrogenase. This subunit contains four 4Fe-4S clusters and is involved in transmitting electrons from the alpha subunit (TIGR01553) at the periplasmic space to the gamma subunit which spans the cytoplasmic membrane. In addition to the gamma proteobacteria, a sequence from Aquifex aolicus falls within the scope of this model. This appears to be the case for the alpha, gamma and epsilon (accessory protein TIGR01562) chains as well. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	7.33309e-156
NZ_CP053618.1|WP_049051928.1|2546240_2546783_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	3.33789e-37
NZ_CP053618.1|WP_006227327.1|2527670_2527886_+|TOBE-domain-containing-protein	gnl|CDD|226113	COG3585, MopI, Molybdopterin-binding protein [Coenzyme metabolism].	8.1723e-19
NZ_CP053618.1|WP_035182973.1|2540569_2541505_+|formate-dehydrogenase-accessory-protein-FdhE	gnl|CDD|377247	pfam04216, FdhE, Protein involved in formate dehydrogenase formation. The function of these proteins is unknown. They may possibly be involved in the formation of formate dehydrogenase.	2.65727e-136
NZ_CP053618.1|WP_157140507.1|2535824_2538893_+|formate-dehydrogenase-N-subunit-alpha	gnl|CDD|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NZ_CP053618.1|WP_047993088.1|2530417_2531362_+|hypothetical-protein	gnl|CDD|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	1.84897e-25

Protein sequences

>NZ_CP053618.1|WP_006387318.1|2532142_2533156_+|sterol-desaturase-family-protein
MDTLSQWFGNCQQWLFETLVQPALFHLGLSNFIEDGYDATMWLLVGLLQVAVLLLVFGPLQRLRPVEPVTDRRQIGIDVLYTLIHRLGVFRLALFFTIDPFWDSVFGQLHIWGFAPFQLDQYWPGVTDQAWVSLIIYLLLFDLVDYLYHRAQHRFAWLWALHAVHHSQRQMTMWSDDRNHLLDDMLRDVVVVFVSQLVGVPPAQFVAIVAITQLAQSFSHANLRMHFGAIGERLLVSPRFHRHHHSIAYDASTPGPAGGYNFAALFPVWDVLFRSARFGVGYGPTGIHDQQPELGGRDYGQGFWSQQWLGLKRMVGRDREPAVTAPPSRPPGAAEGA
>NZ_CP053618.1|WP_020925491.1|2531345_2532140_+|polysaccharide-deacetylase-family-protein
MRRPAKRQLAAAICLALAAQAAGAAPATCDKPVYLTFDTGHMGVAPLIADVLARHHVKVTFFLANERTLTDGSSLDDQWAPWWKARAAEGHVFGSHTYDHVYWQGDLPDGKFRVKPSAGPDTGKRQTWTAEQYCAEIKRSATRFTQMTGKPMLPLYRAPGGKTSPALLRAAKACGFEHVGWAPAGFLGDELPSDKYPNAKLLDQALRTIKPGDILLAHLGIWSRQDPWAPAVLEPLIEGLQRKGYCFATLDTHPAYRDWIATHH
>NZ_CP053618.1|WP_047993088.1|2530417_2531362_+|hypothetical-protein
MALSAAAASAPIFVLNSLDANVSIVDPATYTELRRVPTGKEPHHLYLTPDKKSLMVANATGDSITLMDPKTGEVQRTLTGIVDPYQLQFSPDMKWFVTAANRLDHIDIYAWKPLEKGFDLTLVKRIPAGKTPSHIMIDAKSTTAYVTLQDSDQLIAIDLATQTPKWTVSVGKTPADVFLTPDQKTLLVALTGDSYVEAYDVSKGPAKLISRIKTAAGAHAFRAQGDQRHLFVSNRTANSISRIDLQTLAVVDTFPVPGGPDCMDVLADGKTLLVTSRWARKLTVVDLEQKKVVKQVTVGKSPHGVWTLNHASTR
>NZ_CP053618.1|WP_054485780.1|2529331_2530207_+|DUF2950-family-protein
MMNALVRAPGRWSRRAASVAWLALALLATPAAAQSVYPTPQAAADAFGEALATSDPVALAKVLGPDHRQIVPGGVGQDDVYRFLAAWSRKREVLADGERRAWLSVGDSGWTMPVPIVRVSQGWRFDPAAGKAEIARRAIGRNELNAIDTLRELHAAQIRYRDGVGQGRYADRLVSRPGALDGLYWPELPGYPAQAYGPDALAMGPEVPVADAYYGYRYKVLPARGGDGYWILAWPARYGHTGIGSFVIDARGELREADLGPATARRAATLQGTDVSFGTWNNITPQPIGAK
>NZ_CP053618.1|WP_047993090.1|2528006_2529308_+|DUF3300-domain-containing-protein
MRRLQAWFLGCLCLGLAICLPAAAQTKLDKGQLDQLLAPVALYPDSLLSQVLMGATYPDDIAAAAQWSAAHAGQSGDAAVKAVESESWDPSVKSLVAFPSVMDMMGRQPAWVKSVGDAFLAQPDAVMDSVQRLRAQAKQAGNLKSTPQQKVTSTDAGGKTVVVIEPADPQVVYVPSYNPAVVYGAWPYPAYPPAYYPPPPGSVFATSLVAGIGFGLGVAAVDSMWGGFNWGHNDVDINVNRYNNINVNQRINAANINGNHVAWQHNPANRGNAPYADAASRQKFDGQRQAGLQNRAQGRTPPAPGSRDAARERAAQSFQGRTGQSIEGHTGPRGGNLGQGGAGTRAQGPGHLSAQDRQAAAQRQRADAAAARDRARANNGGSALRDAGNGERMRQQVQRGGESRVAPRGGGGGWHGGGGGHIGGGGGHFGGRR
>NZ_CP053618.1|WP_006227327.1|2527670_2527886_+|TOBE-domain-containing-protein
MSIQSINARNQFRGKIKEIILGPVVSEVDVDTPAGIVTSVITTRSVKELDLQVGTEVLAFVKATEVSVAKL
>NZ_CP053618.1|WP_053499990.1|2526673_2527579_+|ATP-binding-cassette-domain-containing-protein
MFINPNEFELLQHLDVPGRADREPAADEAVPARAALRVTLRQLSKRYGERLVLKGLDLDIAPGEFVAVVGQSGCGKSTLLRLLAGLETPSGAQGGAPARSPVLFDNFPQWSADSRVRMMFQDARLLPWKSVVQNVALGLPGQARAQAAEVLRQVGLGDRGGDWPARLSGGQRQRVALARALVHRPGLLLLDEPLGALDALTRIGMQQLIEDIWRRDGFTAVLVTHDVSEAVALADRILVIDEGRVVLDERVELARPRARGSAAFAALEARVLRVVMKQEAPAAADRPLAPVIQIRHLRLAV
>NZ_CP053618.1|WP_006387311.1|2525814_2526648_+|hypothetical-protein
MSVKRNLLSLALAATLLSLSGAALAADPAKKEIVFGATAGPYSDQIKLGIKPILEKQGYTVRIVEFNDYVQPNFALAQGALDANAFQHIVYLQNFAAKNKLELSELVKVPTAPIAIYSRKYKSVDAAPEGVSVAVPNDPTNQARALVVLQELGWIKLRDGYDPLRVSEKDVAVNAKKIKLIPLEAAQLPRSLEDTDYSFVNGNFALASGLKLTEALALEKTTPTYQNLVAVRTADLDKPFVKDIAAAYASPEFLAVTEKSFAGFVKTDYQQKLAASR
>NZ_CP053618.1|WP_006387310.1|2525135_2525798_+|ABC-transporter-permease
MLDTFVQLLPELGVAVGQTFLMLGIALAASILLGGPLGVLVFLTGPGQSLDRPLAHRLLSWTVNTVRSFPFIILLVALVPFTRVIAGTSIGPVAAAVPLSFAAIPYFARLVEQCLREVPRGVIEAAHAAGASELQIVRRVLLVEARSGLVLALTVLAVSFLSYSAVAGVVGGGGIGDLAIRYGYYRFQTDVMVLTVALLVVLVQIIQFAGNTVARRIDKR
>NZ_CP053618.1|WP_006387309.1|2524326_2525136_+|ATP-binding-cassette-domain-containing-protein
MTDLSSLPDLASLPQPLIRLDAVSKSFATRAGRFDAVRNVSLSIRAGDTFGIIGKSGAGKSTLLRLINLLERPDEGTVRVGGTELTALGKPALRAARQNIGMIFQQFNLLQNETVFENVAFPLRVHGGRGREQIAARVRECLEIVGLTDKTASHPAQLSGGQKQRVAIARALASEPAVLLCDEPTSALDPETTRSVLSVLRDINKRLGVTIVIVTHELAVVRALCRHVAVMENGQVLEQAEISGAGVHLTSALGRELIREATHPYEEVA
>NZ_CP053618.1|WP_054499510.1|2534005_2535553_-|DUF1254-domain-containing-protein
MRRFAPLALSLSLAAPGLAPAPAIAAPALTPAAAATESAREAAMEGYLYFYPLLTLDLTRRQFTHPSQSEQGAPANAFLHTRALPRPGSATPWANPDMLRSSAWLDLSAGPVVLSVPDSQGRLYTLTLLDLWNEAFATIGTRSTGTARGNTAIVPPGWTGTLPSGMPRIDAPTAYVWARSLIQADGPADYPAMHALQDGFTLTPLAQWNLPAQSQRVKADPSLDLKTPVREQVESMPTDAFFTYAAELLRRNPPHATDQPVLAKLRRVGLIPGRPFDFDKLDHPVKQGLRRGLREARERMQAAAGVSLSSVNGWQRETASVGVYGNAYLRRALSAQAQPGAGLPEDLSALLLAADSQGRPLDGAHRYTLHFDGGQLPPAGALWSLAAYDAQGLPVANPIERYTLGERDPLQYNADGSLDLLISHTAPEPGAQANWLPVAAGGPVYVLLRVYAPGPALLDGLWTPPPAVRDDPQPEPEPAPEPEPRAQAATAPAATPPAKAPPGAPATAPGPAKKP
>NZ_CP053618.1|WP_157140507.1|2535824_2538893_+|formate-dehydrogenase-N-subunit-alpha
MVNMNRRQFFKVTGTTLAGSSLALLGAAPGTAMAEVRQYKLARMTETRNTCPYCSVACGLLMYGLGDGAKNARASIMHIEGDPDHPVNRGTLCPKGAALIDFIHSPNRLKYPEYRAPGSDKWERISWDDALTRITKLMKADRDANFVEKTEDGKTVNRWLTTGMLAASASSNEVGYITHKTVRSMGMLAFDNQARVUHGPTVAGLAPTFGRGAMTNHWVDIKNADVVLIMGGNAAEAHPCGFKWVTEAKAHNKAKLIVVDPRFTRSASVADFYAPIRTGTDIIFLGGVIKYLLDHDKIQHEYVRNYTDFSYIVREDFAFDAGLYSGYNADKRTYDKASWDYERGDDGYVKTDPTLAHPRSVYQLLKKHYSRYTEEMVERVCGTPRDKFLKVCEMLASTATTDRAATILYALGWTQHSIGSQIIRTGAMVQLLLGNIGIAGGGMNALRGHSNIQGLTDLGLMSNLLPGYMTLPNEPEQDYGKYIATRALKPLRPNQLSYWQNYGKFHVSLMKAWWGKAATAENNWAFDYLPKLDKLYDMLQVYELMNQGKMNGYLAQGFNPLAAAPNKAKLNAGFAKLKFLVIMDPLVTETSEFWRNAGEANDVDPKQIQTEVFRLPTTCFAEEDGALVNSGRWLQWHWKGAEPPGEAKSDIEIMSLIFTRLRKMYQEEGGKYPDPIVNLSWPYSNPQSPTAEELAKEYSGKALVDLVDPKDPTKVTRKGGEQLAGFAELRDDGSTASGCWIFAGAWGPGGNLMARRDNSDPTGIGQTLNWAWAWPANRRILYNRASCDVAGKPFNPRRSLIAWNGKAWVGADIPDFKGDENPDGGMGPFIMNPEGVARFFARAGMAEGPFPEHYEPFETPLGYNPLYPKAKGVTSNPAARVFKDDLAAMGTVDKFPYVATTYRLTEHFHYWTKNVRINAILQPEQFVEISEVMAKELGIANGSRVKVSSNRGYIKAVALVTKRLRPLTIEGKTVYHVGIPIHWGFVGIAKPGFLTNTLTPFVGDGNSQTPEFKSFLVQVEKI
>NZ_CP053618.1|WP_020925488.1|2538903_2539803_+|formate-dehydrogenase-subunit-beta
MSMQSLDIKRRSATTTPPPGIREPVTGSVAKLIDVSKCIGCKACQSACMEWNDLRDEIGTNVGVYDNPADLTEHSWTVMRFSEYENPQGDLEWLIRKDGCMHCEDPGCLKACPSPGAIIQYTNGIVDFHEENCIGCGYCITGCPFNVPRISKKDHKAYKCTLCSDRVAVGQEPACVKACPTGAIVFGTKDDMKQHAAERIEDLKSRGFEQAGLYDPQGVGGTHVMYVLHHADQPGLYHGLPKEPQISPMVSLWKGIAKPLGVAAMALTALAGFFHYARVGRNEVDEEDERRAEQEIRHE
>NZ_CP053618.1|WP_006387324.1|2539795_2540443_+|formate-dehydrogenase-subunit-gamma
MSDDRHHRRIKRYSPGERTNHWIIAFTFILLALSGLALFHPSMFWLTNLFGGGPWTRILHPFIGLVMFFCFVVFAGHMWRHNLMTKADRQWLSQLNDVVENREDKLPEVGKYNAGQKLLFYVLILCMLGLFASGIVIWREFFAFYFPIWVVRAASVLHAVCALVLICAIIVHIYAAIWVKGSLTAMLRGYVTAGWAWKHHRAWFREQIGKQSTTK
>NZ_CP053618.1|WP_035182973.1|2540569_2541505_+|formate-dehydrogenase-accessory-protein-FdhE
MQRILPRGEIEALDHNTIPRIQLPARDSVFATRAARLRQLAVDSPVADYLLLMARLVDAQQNALRGCNAPPASEDRIALAQAHGMPPLQAVGWPRDPLWRDILRQLVDEVAGGQDVPAEALEVCSALRRALDEDTESLEDLAEAVLSEQHRGVDGAAAPFVMAALQVYWTDLASRFDEKQLPVASPFGVCPVCASLPVASVVRVGGQFEGYRYLCCSLCATQWHMVRVKCSHCEDVESVAYQAIEGRAPAIKAETCDRCHTYRKIFYQDKDLHVEPVADDLASLMLDVLVGEAGYSRASGNPLLWHGAEEE
>NZ_CP053618.1|WP_173010693.1|2541507_2542941_+|L-seryl-tRNA(Sec)-selenium-transferase
MTGLAAAADIPALDRLLNAPALAAALDTHGRTQVVAALRRHLDALRQRALAGELPRAELTQAAVAAAVDGALARAAAPRLRAVYNLTGTVLHTNLGRALLPDEAVASVLRALTTPANLEFDLDSGGRGDRDDLIDDLLCELTGAEAATVVNNNAAAVLLMLNALADRREVVVSRGELVEIGGAFRIPDIMKRAGARLVEVGTTNRTHAADYENAIGPRTAMLMKVHCSNYAVTGFTKSVGVAEVAALAHARGLPATVDLGSGTLVDLTQFGLPREDTVRETIAAGADLVTFSGDKLLGGPQAGLLVGRADLIRKIKKNPLKRALRVGKLTLAALEPVLQLYRAPEFLAQRLTTLRLLTRPQREIQPMAERLRGVLAHAAGADYEVEAVPMYSQIGSGALPVDQLPSHGLAVRYRGKGRPGRHLDRLETRLRHMPVPVIGRIADDALWLDLRCLEARDEAAFTEQLAGLAAQSTEPRA
>NZ_CP053618.1|WP_173010694.1|2542937_2544875_+|selenocysteine-specific-translation-elongation-factor
MIVGTAGHIDHGKTTLVRALTGVDTDRLKEEKARGISIELGYAYTPLPNGDVLGFIDVPGHEKLVHTMAAGASGIDFGLLVVAADDGVMPQTREHLAILALLGVARGAVALTKADRADAARLAAVRGEIAALAADTFLQDAPLFEVCAARAGDAGVARLKQHLDEVAQALGARDGAGLFRLAVDRVFTLAGHGTVVTGTAHGGRARAGDDDADLRLMPAGTRVRVRGIHAQNQPSETGAAGQRCALNLAGIDKSAITRGDWIADARCFLPSRHVDVALTLLPSADAPLRAWTPLHVHIGAARQVAHVVPLSADALAPGQSGWAQLVFDEPVCAMPGDRYIVRNAQATRTVGGGRVLDPNAPDRKRRAPARMQWLQGVADMLDGGGLQPLLAQAALGLDETTLQRLAGRPVRDLAAPEGAIWIEPRTPQGARTLILATHWEALRTRVEQALATFHQGAPDEPGPDGSRLRRMALPAASEALWQGLLEDLRQQGRVLRNGPWLHLPGHTAALAEAEAELALRLLPLLAAGAYDPPWVRDLARAQGEPEERVRQVLRKLLRRGEVAQVVKDLFYHRERVAELVALAIDLAARPEGLNAAAFRDATGLGRKRAIQILEFFDRTGLTRRLRDTHVLRNDSAYLGAGQAVS
>NZ_CP053618.1|WP_054443741.1|2545188_2546223_+|glycosyltransferase
MSHVEPTAPQVSLIVPVYNCERYLSDQLDALLADAALSREVIAVDDGSTDGSVAILQARGATDARLRILRQPHQGLGAARNAGLRAARGAWVAFADADDLLPSAGLARWHEQAVSQGLEVLVGNAYRFTHAPAPLPRSPVLTRQPTAGAMTGEDWIAHCVAIGEWPHYVCLQLVKRELITRHGLAFDPSIFHEDILWTTQLALVARRMGFASEPVYGYRRNPDSITLSPSARIRQWRGVSYVHIIETLLALSRRQDLGQRTRVSIVRHVLHELLCFVDLLRKDVENPQARAQLARSMLDLRAWPRLVRHARGVTDLRRVFKAYRRLRRMARGKGAFTPDMAVTR
>NZ_CP053618.1|WP_049051928.1|2546240_2546783_-|TlpA-family-protein-disulfide-reductase
MVSRRHLLQSALSLAALPGWARAAASDSALKAATGPDWAAWTAATPPLVLPDLAGREQKLAAWRGSVVIVSFWATWCDPCRDEIPLMSAMARRHREEGLRLVAVNVGEALGKITTFLAKWPVAGTVLHDRNSSAAKQWDAVGLPANYLVDRGGRIRHWHLGALDWQAANVNGVVTRMLRA
>NZ_CP053618.1|WP_024067520.1|2546797_2547901_-|transglutaminase-domain-containing-protein
MDRRHFLRFSSALCATQAAALPLAARAGQAPVSADWRSFELTTHIQVRDPGAHARLWIPLPYATDTGYQRGAQSAWLVSGGGSARLAQAPGYDVRMLAVQWPDAQAPREVTVTSRFQTRNRRVDLTQPPPPGASRESAASLREYLQPTELLPTDGIVKTTADRITRGHQGTLARARALYDWVVDNTCRTASTRGCGTGDVRYMLAANDLNGKCADINALFVALARAAGIPARDAYGLRVADSQLGFKSLGKAGDVTRAQHCRAEFYADGYGWVPVDPADVRKVMLEEPPGDLPTTDARVRSARVMLFGAWEMNWVAYNHGHDVVLPGSAHGAVPFLMYPNGETADGRLDSLDPDSFRYTLTARSLST

Crispr_ID: NZ_CP053618_5

• CRISPR_ID: NZ_CP053618_5
• CRISPR_location: 2686980-2687074
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_5

Consensus_repeat	Method
GAATGATCCATGGCGGGCGGCATCGC	CRISPRCasFinder

spacers of NZ_CP053618_5

>5.1|2687006|43|NZ_CP053618|CRISPRCasFinder
TGGCTTTGGCTTGGTGCTGCCGTGGCTCATGCCGGGCATGGAG

CRISPR arrays and Neighbor proteins around NZ_CP053618_5

CRISPR arrays

The CRISPR arrays of NZ_CP053618_5

>merge|NZ_CP053618|5|2686980-2687074|CRISPRCasFinder
GAATGATCCATGGCGGGCGGCATCGCTGGCTTTGGCTTGGTGCTGCCGTGGCTCATGCCGGGCATGGAGGAATGGTCCATGGCGGGCGGCATCGC

>NZ_CP053618|5|5|2686980-2687074|CRISPRCasFinder
GAATGATCCATGGCGGGCGGCATCGC	TGGCTTTGGCTTGGTGCTGCCGTGGCTCATGCCGGGCATGGAG
GAATGGTCCATGGCGGGCGGCATCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_006386844.1|2678030_2678669_+|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl|CDD|225415
NZ_CP053618.1|WP_006386852.1|2682152_2682584_-|VOC-family-protein	unknown	unknown	gnl|CDD|319945
NZ_CP053618.1|WP_006386853.1|2682725_2683601_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176118
NZ_CP053618.1|WP_006386856.1|2685727_2686204_-|DUF411-domain-containing-protein	unknown	unknown	gnl|CDD|225564
NZ_CP053618.1|WP_054439324.1|2681393_2682128_-|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl|CDD|367142
NZ_CP053618.1|WP_006386866.1|2696761_2698315_+|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB	unknown	unknown	gnl|CDD|235310
NZ_CP053618.1|WP_173010711.1|2689066_2689567_-|cupredoxin-family-protein	unknown	unknown	gnl|CDD|259873
NZ_CP053618.1|WP_006386863.1|2693969_2694746_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	unknown	unknown	gnl|CDD|234689
NZ_CP053618.1|WP_006386862.1|2693109_2693808_-|phosphate-regulon-transcriptional-regulator-PhoB	unknown	unknown	gnl|CDD|131209
NZ_CP053618.1|WP_020925379.1|2689641_2691042_-|heavy-metal-sensor-histidine-kinase	unknown	unknown	gnl|CDD|273593
NZ_CP053618.1|WP_049053062.1|2683673_2684258_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|372434
NZ_CP053618.1|WP_006386855.1|2684381_2685581_-|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|236985
NZ_CP053618.1|WP_006386846.1|2679569_2680340_-|LamB/YcsF-family-protein	unknown	unknown	gnl|CDD|235446
NZ_CP053618.1|WP_049053066.1|2680395_2681397_-|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NZ_CP053618.1|WP_173010710.1|2687254_2689048_-|copper-resistance-system-multicopper-oxidase	unknown	unknown	gnl|CDD|273649
NZ_CP053618.1|WP_024067599.1|2696119_2696758_+|SCP2-sterol-binding-domain-containing-protein	unknown	unknown	gnl|CDD|225706
NZ_CP053618.1|WP_006386860.1|2691038_2691725_-|heavy-metal-response-regulator-transcription-factor	unknown	unknown	gnl|CDD|130454
NZ_CP053618.1|WP_049053057.1|2691789_2693097_-|phosphate-regulon-sensor-histidine-kinase-PhoR	unknown	unknown	gnl|CDD|274368
NZ_CP053618.1|WP_038502736.1|2694923_2695925_+|Tim44-domain-containing-protein	unknown	unknown	gnl|CDD|214950
NZ_CP053618.1|WP_173010708.1|2678779_2679481_+|GntR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224715

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_006386844.1|2678030_2678669_+|trimeric-intracellular-cation-channel-family-protein	gnl|CDD|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	3.02251e-74
NZ_CP053618.1|WP_006386852.1|2682152_2682584_-|VOC-family-protein	gnl|CDD|319945	cd08357, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) familyprotein, glyoxalase I, and type I ring-cleaving dioxygenases. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.46103e-72
NZ_CP053618.1|WP_006386853.1|2682725_2683601_+|LysR-family-transcriptional-regulator	gnl|CDD|176118	cd08427, PBP2_LTTR_like_2, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.2515e-70
NZ_CP053618.1|WP_006386856.1|2685727_2686204_-|DUF411-domain-containing-protein	gnl|CDD|225564	COG3019, COG3019, Predicted metal-binding protein [General function prediction only].	1.1634e-51
NZ_CP053618.1|WP_054439324.1|2681393_2682128_-|5-oxoprolinase-subunit-PxpB	gnl|CDD|367142	pfam02682, CT_C_D, Carboxyltransferase domain, subdomain C and D. Urea carboxylase (UC) catalyzes a two-step, ATP- and biotin-dependent carboxylation reaction of urea. It is composed of biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier protein (BCCP) domains. The CT domain of UC consists of four subdomains, named A, B, C and D. This domain covers the C and D subdomains of the CT domain. This domain covers the whole length of kipI (kinase A inhibitor) from Bacillus subtilis. It can also be found in S. cerevisiae urea amidolyase Dur1,2, which is a multifunctional biotin-dependent enzyme with domains for urea carboxylase and allophanate (urea carboxylate) hydrolase activity.	8.87136e-89
NZ_CP053618.1|WP_006386866.1|2696761_2698315_+|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB	gnl|CDD|235310	PRK04750, ubiB, putative ubiquinone biosynthesis protein UbiB; Reviewed.	0
NZ_CP053618.1|WP_173010711.1|2689066_2689567_-|cupredoxin-family-protein	gnl|CDD|259873	cd04211, Cupredoxin_like_2, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	9.746e-56
NZ_CP053618.1|WP_006386863.1|2693969_2694746_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	gnl|CDD|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	7.29121e-131
NZ_CP053618.1|WP_006386862.1|2693109_2693808_-|phosphate-regulon-transcriptional-regulator-PhoB	gnl|CDD|131209	TIGR02154, PhoB, phosphate regulon transcriptional regulatory protein PhoB. PhoB is a DNA-binding response regulator protein acting with PhoR in a 2-component system responding to phosphate ion. PhoB acts as a positive regulator of gene expression for phosphate-related genes such as phoA, phoS, phoE and ugpAB as well as itself. It is often found proximal to genes for the high-affinity phosphate ABC transporter (pstSCAB; GenProp0190) and presumably regulates these as well. [Regulatory functions, DNA interactions, Signal transduction, Two-component systems].	7.41786e-143
NZ_CP053618.1|WP_020925379.1|2689641_2691042_-|heavy-metal-sensor-histidine-kinase	gnl|CDD|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	1.42301e-115
NZ_CP053618.1|WP_049053062.1|2683673_2684258_+|HD-domain-containing-protein	gnl|CDD|372434	pfam13023, HD_3, HD domain. HD domains are metal dependent phosphohydrolases.	2.9368e-69
NZ_CP053618.1|WP_006386855.1|2684381_2685581_-|phosphoglycerate-dehydrogenase	gnl|CDD|236985	PRK11790, PRK11790, phosphoglycerate dehydrogenase.	0
NZ_CP053618.1|WP_006386846.1|2679569_2680340_-|LamB/YcsF-family-protein	gnl|CDD|235446	PRK05406, PRK05406, 5-oxoprolinase subunit PxpA.	1.26432e-144
NZ_CP053618.1|WP_049053066.1|2680395_2681397_-|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	8.21283e-120
NZ_CP053618.1|WP_173010710.1|2687254_2689048_-|copper-resistance-system-multicopper-oxidase	gnl|CDD|273649	TIGR01480, unnamed_protein_product, copper-resistance protein, CopA family. This model represents the CopA copper resistance protein family. CopA is related to laccase (benzenediol:oxygen oxidoreductase) and L-ascorbate oxidase, both copper-containing enzymes. Most members have a typical TAT (twin-arginine translocation) signal sequence with an Arg-Arg pair. Twin-arginine translocation is observed for a large number of periplasmic proteins that cross the inner membrane with metal-containing cofactors already bound. The combination of copper-binding sites and TAT translocation motif suggests a mechansism of resistance by packaging and export. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NZ_CP053618.1|WP_024067599.1|2696119_2696758_+|SCP2-sterol-binding-domain-containing-protein	gnl|CDD|225706	COG3165, COG3165, Uncharacterized protein conserved in bacteria [Function unknown].	4.25521e-22
NZ_CP053618.1|WP_006386860.1|2691038_2691725_-|heavy-metal-response-regulator-transcription-factor	gnl|CDD|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	5.39101e-109
NZ_CP053618.1|WP_049053057.1|2691789_2693097_-|phosphate-regulon-sensor-histidine-kinase-PhoR	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	4.37143e-157
NZ_CP053618.1|WP_038502736.1|2694923_2695925_+|Tim44-domain-containing-protein	gnl|CDD|214950	smart00978, Tim44, Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by electrostatic interactions and by penetrating the polar head group region.	4.41823e-27
NZ_CP053618.1|WP_173010708.1|2678779_2679481_+|GntR-family-transcriptional-regulator	gnl|CDD|224715	COG1802, GntR, Transcriptional regulators [Transcription].	8.68245e-32

Protein sequences

>NZ_CP053618.1|WP_006386856.1|2685727_2686204_-|DUF411-domain-containing-protein
MKTPLIPARRLLLAAALSLPLYAAPILAQAQSAPKVQVWKTPTCGCCEDWVKHMRDNGFEVTTHDVQDTGPVRRNAGMADYGSCHTAVVDGYAIEGHVPASDVRRLLLEKPDAAGLAAPGMPLGSPGMDGPEYGGRKTPHDVLLVDKRGGAKVFQAYR
>NZ_CP053618.1|WP_006386855.1|2684381_2685581_-|phosphoglycerate-dehydrogenase
MAHIVLFENIHPSARAVFEAAGYTDIVTHAAALPPAQLQDALRGAQVAGIRSRTHLDAALLSGNPDLRVVGCFCIGTNQVDLDTAMQRGIPVFNAPFSNTRSVAELVLGEAILLLRRIPEKNARVHLGHWDKSAAGAFETRGKTLGIVGYGNIGSQISTLAEGLGMRVIYHDVEAKLPLGNARPAGSLNDLLEQADVVTLHVPGGKSTENIMNAETIARMRRGAILINASRGTVVDIDALHAALKSGHLAGAALDVFPTEPKGADEPLASPLIGLPNVILTPHIGGSTQESQENIGREVAEKLVRFLQAGTTKGAVNFPELPYLEQAGATRILHVHRNAPGALGTLDNLMAQHGLNIVSQTLQTKGQIGYVITDVDGEVDDLVMTTLRDHPITVRCDRL
>NZ_CP053618.1|WP_049053062.1|2683673_2684258_+|HD-domain-containing-protein
MASTSLEKQLQFLREIDRLKTVVRQSPLLDRSRKENSAEHSWHLALYALVLSEYASGPVDTQRVMRMLLLHDVVEIDVGDFPIHGGSSAAWQAEHEDKAAQRLFGLLPSPQGDEFLALWREFEQAESEDARFAKALDRFQPLLINVFTGGGTWTENGVSREQVLARYGPVIQRGAPKLWDVCERWVAAHFAGRA
>NZ_CP053618.1|WP_006386853.1|2682725_2683601_+|LysR-family-transcriptional-regulator
MIKEFKTFIAVARDGTFTGAGAQLGLTQSAVSAQIKRLEDYLGVALFDRSARAAVLNDHGREMLPQAEELVAMAERMASTAGAGHVSGSLRIGAIASVQQDLLVRALGEFRAGYPDVRVRIVPGVSLSLLGQVDAGEVDMALLIRPPFALPPELGWQPLLREEVVLAMPAAMALAPWREVLAAQPFIRYDRASFGGRVVDLFLKKQRITVHEAVELDEIEAIANMVRHGLGVALLPRLRGLDTDGLRLVSLGDAAFHREIGLIGRLPFDAGSVRGKMAECLARAAGAALAP
>NZ_CP053618.1|WP_006386852.1|2682152_2682584_-|VOC-family-protein
MTAQTNLPPFHLAFPVRDLAEARAFYGEKLGCPEGRSSPEWIDFNFYGHQIVAHLAPSECGHKATSAVDSHNVPVRHFGAVLSMEQWEAMAKRLTDAGTEFVIEPYIRFKGEVGEQATMFFLDPSGNALEFKAFKNLDSLFAK
>NZ_CP053618.1|WP_054439324.1|2681393_2682128_-|5-oxoprolinase-subunit-PxpB
MNATPDPSSSAEATWRIQPQGDRCLIVSFGDRIDAAVGRTCLAAARKLRDAGLPGVTDVVPSFVAVAVHYRPDGLGHGPTYADLAERIEALLADGIAADNAAGREVDVPVCYGGEHGPDLDEVARAAGLTPDEVIALHSGPRSMVFMLGFAPGHAYLGVHDEKLNLPRRPSPRTAVPAGAVAIANRQTVIYPNRLPGGWHIIGTTPLTMFDPAREPAAYLQPGDSVRFVPISADEFARLRGNRS
>NZ_CP053618.1|WP_049053066.1|2680395_2681397_-|biotin-dependent-carboxyltransferase-family-protein
MSITIIKPGMLSSFQDRGREGYQHQGIPAAGAMDERAHRLANALAGNSGDPATLEMTLTGPTLRFDAPACFALAGADLGATLNGQEIPQHRPLVARAGDTLAFGARPANGVRGYLAVHGGFALAPVMGSETTYLRSGFGGFEGRALAKGDQVGLRQALDGHGLDALQKALWDLRIYLPGTLGHKQRDAIRFLPGMQWQEFSEASRHAFGGSEFRISPQSDRMGYRLQGPALSMSQPRQMLSEAACFGTVQVPSGGEAIILMADRQTTGGYPKIAQIASVDLPLLAQYAPGRALRFAMIELDEAQRLDGERERAFAQLLDALAPLRALLGPGHP
>NZ_CP053618.1|WP_006386846.1|2679569_2680340_-|LamB/YcsF-family-protein
MSTSIDLNCDMGESYGAWSMGNDAAVLAFVSSANIACGFHGGDPATMRKTVAAALKQGVALGAHPSLQDLVGFGRRAIPITPDEAYDITVYQIGALAGVAASQGARLHHVKAHGALYNMAAKDEGLARAICQAVKDVDATLLLYGLAGSKLIDAARAIGLAAANEVFADRSYQDDGSLTPRTRAGAMIEDVDQAVAQVVRMVREGKVRSVDGKDVPVQADTLCIHGDQPNALVFARAIREALERAGIAVRTPSARA
>NZ_CP053618.1|WP_173010708.1|2678779_2679481_+|GntR-family-transcriptional-regulator
MDVKAPATIPYFLQEQIRELIVDGTIRPGQPLREQELEQRFGTSRSPIREALRLLELSGLVTHVQRKGFRVTLYSETQIRHLYKLRAELEAYCIRQVAEIDDISPLVVELRAYDEAIAAAMAKRDVRAYIAALREFYLAGARFTGNAPLAEVLTKLYEQVEPLRYLLARQTMESNRLQTYTQGITQALASRDFDRAAELTRGYVLDVLPGILRAYHEASLQDAEEPAPRYGRA
>NZ_CP053618.1|WP_006386844.1|2678030_2678669_+|trimeric-intracellular-cation-channel-family-protein
MFYDLSPALLHTLYLVAIVAEAMTAALSAGRRDMDWMGVCIIACVTALGGGSLRDVLLGHYPLTWVVHPEYLWMTAGAALLTALIAPVMRRLRSVFLLADALGLVAFTVIGCQVAQLMQLPITVVLISGMITGCAGGVLRDVLCNEVPLLFRKELYASVSVVTGALYLGAQALGLPANAAVPIALAVGLALRLLALRFNWQMPKFVYRDDWH
>NZ_CP053618.1|WP_173010710.1|2687254_2689048_-|copper-resistance-system-multicopper-oxidase
MKTFPIPTRRRFVQGLAAGGALAALGGWRAASAGPRAAQAAAAPAELRGTEFHLEIGETPVNYTGAARIATTVNGQVPAPLLRWREGDTVTLHVTNRLREQTSIHWHGILLPTEMDGVPGLSFPGIDPGQTFTYRFDVRQSGTYWYHSHSGFQEQTGLYGAIVIDPKRPDPIAADRDYTVLLSDWTDEDPMRVFDKLKAMPDYYNRNQPSVESLIREAGEKGWRTALSERLMWEQMRMNPSDLADVSGATYTFLTNGATPAGNWTGLFKPGERVRLRFINGSAMTYFDVRIPGLKMTVVAADGQDVRPVDVEEFRIAVAETYDVIVEPAEDRAYTIFSQAMDRSGYARATLAPRPGMQAEVPAVDRVQLLGMMDMGMKHDMGGMDHGAAPEATAGAMAGMNHGAMPGMDHGSSHGGGADQGGIVEVRHPYPEERGPGNSMLPDVVSTRLDDPGIGLRDNGRRVLTYADLRSIREPDDNRAPTREIELHLTGNMERYMWSFNGVKFSDAKPIVLRYGERVRFVLVNDTMMTHPIHLHGLWSDLESPDGAFQVRKHTLSLNPAQRLSYRVSADARGNWAYHCHLLYHMEAGMFRAVVVE
>NZ_CP053618.1|WP_173010711.1|2689066_2689567_-|cupredoxin-family-protein
MKGTLLRITQITALAALLGTGTGTAFAAGAHGEHAGHAMPAASAPIGTPGDAARVTRSIDIDMTDAMRFTPAQVQVKAGETVRFNVRNSGRIRHEMVLGTDADLQAHYAMMMKDPGMRHEEANAISLEGGKSGQIVWKFDRAGTVSFGCLEPGHYTAGMKGAVSVQ
>NZ_CP053618.1|WP_020925379.1|2689641_2691042_-|heavy-metal-sensor-histidine-kinase
MKPPRVRSMQARLTLLLGAIALLVSSLAGATLFWALKREVERQEITEVSGKLELINHLIDMQNNARGLHDLAATFDDMRAGQSQLGIWIVDAQGHPVYGGAIPETLQVLPDRQVLLQQADGSRLRGLRVAVDDRILPGAQLTVAVSTRTSSQFLYAYGTALALICALWVGATVVLAAWAVRRSMAPTRRLSEQAARIQPDNLAVRLPLRDTDRELHELVLSFNRTLERLQAAYQQMEGFNADVAHELRTPLATLINGTQVTLSSGRDAAELRDALESNLETLEDLKTLVNDMLFLARADRGERAADLAPVSLAAEARRVADFYEAALEDRGVTLRCDGDAIVAANPGLVRRALANLISNAIKATPRGGEIVLACQPRPAGARVEVRNPGAPIPAADLPRIFDRFFRSGQARAPRSEGHGLGLAIVRAIARMHGGEVDAASGADGTVVGITLRGSGPDTAGGHITKK
>NZ_CP053618.1|WP_006386860.1|2691038_2691725_-|heavy-metal-response-regulator-transcription-factor
MRILVIEDEPKLADYLKKGLSEQSHVVDLARDGVNGLHLALEGAYDLIVLDVMLPGVDGFGILAAVRANKDTPILMLTARDAVEDRVRGLEGGADDYLIKPFAFSELLARVQALLRRGRSQEPTVFRLADLELDLARRKVARGGRRLDLTAKEFNLLALLLRRQGQVLSRTTLAEQVWDMNFDSDTNVIDVAVRRLRSKLDDPFEAKLLHTVRGMGYVLESRPEPARG
>NZ_CP053618.1|WP_049053057.1|2691789_2693097_-|phosphate-regulon-sensor-histidine-kinase-PhoR
MIWLRTLILVALWAAIALLAQWLIGDPAGWALFSAALVVMLLWRSWRLHLVSHWARHPDTSPPASVGPWDDILAPLYRYTRARARELAETRDTMQGMLAAAQALPDGAVTLNEDFQIDWCNRMARQHLGLRLPADRGHNLLNLLRAPEFVEYAHRASWPDPILVRLGQNGQERLMMMQLTAYASNQRLLITRDVTQIERLETTRRDFVANVSHELRTPLTVLAGFLETLRDMPADALPPEQRAQYLDMMHEQAQRMQAIVEDLLTLSTLESSPGSDPRAVNMGALLQKARQQIEALSGGRHVIEWHIDETVDVLGAETELTSALSNLLTNAVRYTPDGGTITVRWEREADGGGRYSVQDTGIGIPARHIPRLTERFYRVDRGRSRAVGGTGLGLAITKHIAMRHDAELLISSEPGKGSLFALRFPPDRIAVDPSA
>NZ_CP053618.1|WP_006386862.1|2693109_2693808_-|phosphate-regulon-transcriptional-regulator-PhoB
MSSTILVVEDEPAIQELIAVNLSFAGHKVLRAFDADQAQTLIRAELPDLILLDWMLPGTSGLAMARKLRNDERTRAVPVIMLTAKGSEQDKVDGLEAGADDYITKPFSPKELMARIKAVLRRRAPQLTDDVIDVGGLKLDPVTHRLSGNSQSLQIGPTEFRLLHFFMTHPERVFSRSQLLDQVWGDHVFVEERTVDVHIRRLRKALEPSGHDAHVETVRGSGYRFTAQVPAR
>NZ_CP053618.1|WP_006386863.1|2693969_2694746_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE
MQNPSESQHSADSASQSTHFGFQSVPESEKARKVAEVFHSVAQRYDIMNDFMSAGLHRVWKAFTIGRAAIRPGMKVLDIAGGTGDLAKAFAKRAGPTGEVWLTDINDSMLRVGRDRLADAGQLVPTAVCDAERLPFPTGYFDRVSVAFGLRNMTHKDRALAEMTRVLKPGGKLLVLEFSRIAKPLAPAYDWYSFNVLPWLGKTVAKDEASYRYLAESIRMHPDQETLADMLRTAGLERVQYFNLTAGIAALHEGVRLA
>NZ_CP053618.1|WP_038502736.1|2694923_2695925_+|Tim44-domain-containing-protein
MTKFCFSRFVAAALIAISGAALVTASFDAEARRAGGGSSVGRQSSNVTQQRQATTPPTAASNTAGATAAPAAAGAATAGAAGAAAKSGASRWLGPIAGIAAGLGIAALLSSMGLSGAFAEFLSSALLIALVVFAVMFIIRRLRGAAPRPATQGAFGGANNAPGQPQQQPMWREALKPTAPAAAPVAAAAAAPAAVLPKAGDDNNWFVPGDFDTPNFLKQAKEQFVRIQAVWDSGSTDRLRDYLTDDLITELKPQLAERGAAPNKTEVVLLNAELLGIETVSDGHLASVRFSGMLRETPGAEAFRFEEVWNLFKPANGGWLLAGIQQIPVEYAS
>NZ_CP053618.1|WP_024067599.1|2696119_2696758_+|SCP2-sterol-binding-domain-containing-protein
MSPFSFLPTPARLAVGALNALLKREDWARERLARHAGKTVRFALGGFTLGLTIDSEGLAAQADAAVVPDVTLTVAPERLPLPRLGAGGETPDFAEATHISGDAALAQVVADLSKQLRWDPEDSLARLVGDIPALRIVGGLRAATGGARQAGQRLAENVSEYLAEENGMLLGRPALEQWRLDLAELNARADALARSAAALQSRLATAAGKRGA
>NZ_CP053618.1|WP_006386866.1|2696761_2698315_+|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB
MFPLLRLFRIILVSLRYGLDELVLSSLNHPLATCLLRVIRLGTRPRKPRGLRLRLALESLGPIFVKFGQVLSTRRDLIPADIANELALLQDRVPPFPSAQAAACIEAALGAPPEKLFAQFQVDPVASASIAQVHFAVLHDGREVAVKVLRPGMLSIIEKDLSLLKIVARIIERLGADGRRLKPREVVAEFDKYLHDELDLVREASNCSQLRRNFGPESGRGDMLMVPEVIWEYTASTVFTMQRMYGVPVGQVERMRAAGIDIPTLARTGVEIFFTQVFTDGFFHADMHPGNIYVSDRPETLGSYIALDFGIVGSLSEFDKNYLAQNFLAFFHRDYRRVAQLHIESGWVPPDTREEELEGAVRAVCEPYFDRPLSEISLGQVLLRLFQTSRRFNVEIQPQLVLLQKTLLNVEGLGRQLDPNLDLWKTAKPYLERWMRQRVGIKGLRQSLEKEAAQWSQMLPALPRLVHDHLNRPNLSPALLAEMAQLRRAQEQSNRLVAALVGVLALGIGVALWALTR

Crispr_ID: NZ_CP053618_6

• CRISPR_ID: NZ_CP053618_6
• CRISPR_location: 3127570-3127664
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_6

Consensus_repeat	Method
GCCGTGGGGGCCGGCATCGGCGC	CRISPRCasFinder

spacers of NZ_CP053618_6

>6.1|3127593|49|NZ_CP053618|CRISPRCasFinder
CGCCGTGGGGGCCGGCATCGGCGCCCTGATCGGCCATGGCACCGGCGCG

CRISPR arrays and Neighbor proteins around NZ_CP053618_6

CRISPR arrays

The CRISPR arrays of NZ_CP053618_6

>merge|NZ_CP053618|6|3127570-3127664|CRISPRCasFinder
GCCGTGGGGACCGGGGCCGGCGCCGCCGTGGGGGCCGGCATCGGCGCCCTGATCGGCCATGGCACCGGCGCGGCCGTGGGCGCCGGCATCGGCGC

>NZ_CP053618|6|6|3127570-3127664|CRISPRCasFinder
GCCGTGGGGACCGGGGCCGGCGC	CGCCGTGGGGGCCGGCATCGGCGCCCTGATCGGCCATGGCACCGGCGCG
GCCGTGGGCGCCGGCATCGGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_053498611.1|3121775_3122765_+|oxidoreductase	unknown	unknown	gnl|CDD|99782
NZ_CP053618.1|WP_054506604.1|3125742_3126366_-|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224103
NZ_CP053618.1|WP_173010760.1|3126708_3127392_+|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|319787
NZ_CP053618.1|WP_020925100.1|3128135_3128462_+|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl|CDD|234845
NZ_CP053618.1|WP_053498613.1|3122829_3123708_+|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl|CDD|223257
NZ_CP053618.1|WP_053498610.1|3120322_3121543_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_CP053618.1|WP_053500619.1|3128970_3129192_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_006388841.1|3128518_3128974_-|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224759
NZ_CP053618.1|WP_054444384.1|3131816_3132503_-|nucleotidyltransferase-family-protein	unknown	unknown	gnl|CDD|133044
NZ_CP053618.1|WP_026382364.1|3124707_3125634_+|transporter	unknown	unknown	gnl|CDD|226763
NZ_CP053618.1|WP_081004668.1|3119059_3120031_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|197666
NZ_CP053618.1|WP_047992630.1|3121549_3121774_+|ferredoxin	unknown	unknown	gnl|CDD|379145
NZ_CP053618.1|WP_054446920.1|3123781_3124594_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|200567
NZ_CP053618.1|WP_104413893.1|3132502_3133543_-|phosphotransferase	unknown	unknown	gnl|CDD|225719
NZ_CP053618.1|WP_053500627.1|3133711_3136105_+|LPS-assembly-protein-LptD	unknown	unknown	gnl|CDD|224369
NZ_CP053618.1|WP_006388844.1|3130958_3131657_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_173010762.1|3137685_3138477_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl|CDD|234708
NZ_CP053618.1|WP_053500629.1|3136101_3137667_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|236758
NZ_CP053618.1|WP_173010761.1|3129188_3130823_-|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|236158
NZ_CP053618.1|WP_127481515.1|3126410_3126614_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_053498611.1|3121775_3122765_+|oxidoreductase	gnl|CDD|99782	cd06185, PDR_like, Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur [2Fe-2S] cluster domain. Although structurally homologous to FNR, PDR binds FMN rather than FAD in it's FNR-like domain. Electron transfer between pyrimidines and iron-sulfur clusters (Rieske center [2Fe-2S]) or heme groups is mediated by flavins in respiration, photosynthesis, and oxygenase systems. Type I dioxygenase systems, including the hydroxylate phthalate system, have 2 components, a monomeric reductase consisting of a flavin and a 2Fe-2S center and a multimeric oxygenase. In contrast to other Rieske dioxygenases the ferredoxin like domain is C-, not N-terminal.	2.60949e-68
NZ_CP053618.1|WP_054506604.1|3125742_3126366_-|NAD(P)H-dependent-oxidoreductase	gnl|CDD|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	6.84213e-33
NZ_CP053618.1|WP_173010760.1|3126708_3127392_+|HAD-IA-family-hydrolase	gnl|CDD|319787	cd02588, HAD_L2-DEX, L-2-haloacid dehalogenase. L-2-Haloacid dehalogenase catalyzes the hydrolytic dehalogenation of L-2-haloacids to produce the corresponding D-2-hydroxyacids with an inversion of the C2-configuration. 2-haloacid dehalogenases are of interest for their potential to degrade recalcitrant halogenated environmental pollutants and their use in the synthesis of industrial chemicals. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.43826e-25
NZ_CP053618.1|WP_020925100.1|3128135_3128462_+|4a-hydroxytetrahydrobiopterin-dehydratase	gnl|CDD|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	5.33645e-45
NZ_CP053618.1|WP_053498613.1|3122829_3123708_+|fumarylacetoacetate-hydrolase-family-protein	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.24383e-82
NZ_CP053618.1|WP_053498610.1|3120322_3121543_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.11618e-76
NZ_CP053618.1|WP_104413893.1|3132502_3133543_-|phosphotransferase	gnl|CDD|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	8.88275e-106
NZ_CP053618.1|WP_006388841.1|3128518_3128974_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	9.40517e-15
NZ_CP053618.1|WP_054444384.1|3131816_3132503_-|nucleotidyltransferase-family-protein	gnl|CDD|133044	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family. This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.	1.27193e-82
NZ_CP053618.1|WP_026382364.1|3124707_3125634_+|transporter	gnl|CDD|226763	COG4313, COG4313, Protein involved in meta-pathway of phenol degradation [Energy production and conversion].	2.49644e-28
NZ_CP053618.1|WP_081004668.1|3119059_3120031_-|cupin-domain-containing-protein	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.7131e-24
NZ_CP053618.1|WP_047992630.1|3121549_3121774_+|ferredoxin	gnl|CDD|379145	pfam13370, Fer4_13, 4Fe-4S single cluster domain of Ferredoxin I. Fer4_13 is a ferredoxin I from sulfate-reducing bacteria. Chemical sequence analysis suggests that this characteristic [4Fe-4S] cluster sulfur environment is widely distributed among ferredoxins.	8.08817e-05
NZ_CP053618.1|WP_054446920.1|3123781_3124594_+|polysaccharide-deacetylase-family-protein	gnl|CDD|200567	cd10942, CE4_u11, Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily. This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.	1.19381e-74
NZ_CP053618.1|WP_053500627.1|3133711_3136105_+|LPS-assembly-protein-LptD	gnl|CDD|224369	COG1452, Imp, Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane].	1.00244e-135
NZ_CP053618.1|WP_173010762.1|3137685_3138477_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl|CDD|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	4.09572e-134
NZ_CP053618.1|WP_053500629.1|3136101_3137667_+|peptidylprolyl-isomerase	gnl|CDD|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	7.88378e-95
NZ_CP053618.1|WP_173010761.1|3129188_3130823_-|FAD-dependent-monooxygenase	gnl|CDD|236158	PRK08132, PRK08132, FAD-dependent oxidoreductase; Provisional.	0

Protein sequences

>NZ_CP053618.1|WP_173010760.1|3126708_3127392_+|HAD-IA-family-hydrolase
MSAVAEPAAYPRVVLFDLLTALLDSWTVWNAAAGSEARGRAWRAEYLRLTYGCGAYQPYEQLVEAAAVTVGLPASAPAALEAGWDQLAAWDGARELLAALRPHCRLGVVTNCSRRLGHRAAALLGVDWDVVVTSEEAGYYKPDPRPYQLALARLETPASQAAFVAGSGYDLFGTSKVGLATYWHNRVGLALPAGAPAPAAQSARLEDALPWLARFGGAGRDGTNCCA
>NZ_CP053618.1|WP_127481515.1|3126410_3126614_-|hypothetical-protein
MLAGLREVGTAGVRGAIQGSAGDRHDHENVPSGGARTRGAAGLAIESGHDKIAFETIAIAIILPGVA
>NZ_CP053618.1|WP_054506604.1|3125742_3126366_-|NAD(P)H-dependent-oxidoreductase
MRLLNIESSPRGPRSASISIANAFIDAYGKACPALQVDTLNVWEEDLPEFDGKAIGAKYKGVSKEPLDPAEASIWTRIGALARRFQQADRIVLGVPMWNFDYPYKLKQLIDLVSQRGMLFGFDGKAYEPLLGIPRALVIHVRGQSHDPSTYAASPGFAHQADYLDFWLRFIGVKEIRRLMVEHTWDGRATETIARGRADAAAMAADF
>NZ_CP053618.1|WP_026382364.1|3124707_3125634_+|transporter
MRRLIIPGMLALALSRGVMAAQGVTFGGPVGGTDIQSAYLPPEAGFYGSLIAVGAYGDRFYDNAGMSPTTSVRLPGGIAEFGLLYVYPQKLFGGTLASSVASGYSWGSITVNGKRQNFQGMNDIYTDVLMWSKHLGTIEGGRPRGLTMKLGYSMVLPTGKYDSADLYSPGRHTYYYIPNGAFTYLTGPNFLGDGTEFSMSYFLDIAGKNSANGYKNGLVADVDVAVSEVVGRWQLGVAGYYARQLTDDKVNGERRSGNRFAGAAVGPVVSYNIPDCKCSVKFKAQFSVFTRNSLAPNAAYLFFNKAFN
>NZ_CP053618.1|WP_054446920.1|3123781_3124594_+|polysaccharide-deacetylase-family-protein
MLCITFDNFGSAAGEQLPWGCPADVPSAEWDAYNRLGLELGHPRILKLLADLKIRCTYFAEGYAAERYPEEMKRWHGAGHEIAVHGWRHESWLDIASREEENRLIERAVTSIRTLTGEAPVGFRPPGLAINGWTDDVLQAHGIRYVSQALPATDGGASSRASTVVSRLDVLPTEPALIDGAMIHPRFGGIFGALDDAAAYDKFYQLAVAHETSRPQEPWVLVVHPFTSGNRAWFGFEDFMRRLAGEFGSSRFGLARDLASKTTAAGAGPR
>NZ_CP053618.1|WP_053498613.1|3122829_3123708_+|fumarylacetoacetate-hydrolase-family-protein
MKLAMFREGGKDRIGVVEADTIVDVTAGLPSLSPDLFDWLPGLATSWQVLALLARESKTRLPLSSVRLLPPIRRPSTFLAIGGNYESHLREIARLKIQVGEHQVWFNKQVSCISGPFDDLVIPAGMSTLDYEVELAVIIGRRCRNVPARHAVDYIAGYTVCNDASVRERHGRSPTMTLAKSFDSLGPLGPWMTTVDEIPDPHALRIRTWVNGDLRQDGSTADMRFNIFEQIEELSHAMTLEPGDVLATGTPAGIGAARQPPIFLAPGDVVRMQIENIGEIENRVVAAGSVRA
>NZ_CP053618.1|WP_053498611.1|3121775_3122765_+|oxidoreductase
MDDQTRRRAMSEWRPMRLADRYRLAERIFALKLVDEHGASLSEIAPGDHVEVRVPGGTRAYSLCNAPGERDHYLLGIHHSSLHGGAHYLCDTCDVGDTLQVRGPGNFFSLSPQHRRIVLVAGGIGITPIISMAQHLASQGLDFEMHYCARSYAAAAFVDRIDASAYRDRVCYHFDDDPAHQKLDLDALFSGLGADQHVYLCGPNAMLAEALTLRERYALSHRLHYERFGASPSDSTGAAVDTGFEVCTARSGRRIEVPAGCSIATALNRAGVEVPLSCEQGVCGMCLTRVLDGIPDHRDDVLSDAERAANDVILPCVSRARSAVLTLDL
>NZ_CP053618.1|WP_047992630.1|3121549_3121774_+|ferredoxin
MNQVIVQIQGGMCCGFGNCAGLCPQVFRLDYETNRAQLVPDAQLDVHAEQIARAASECPTQAIFFFRSGDDAWA
>NZ_CP053618.1|WP_053498610.1|3120322_3121543_+|cytochrome-P450
MQSLDTPDLKSADFLADRYPTYRRLQKDFPLFDIEINGESCKVLTRYRDVDEVLRNPLATVQQAPGEFPERIGKGAASRFYRESLPNIDAPDHTRIRRIVTPAFNPKTVANMRGWVEKVIVDHLDRLAGAGEIDFVSAFADPVPAEIACRLLHVPVSDAAGLFARQHGLNAVLSVADITPERLAEADASAAFYYEYMDDVLDALKGKLPEDDFVGALMAAEDADNGLTRSELVTTLIGFLVASYHTTKVAMSNAVLAFLNHDDERARLVAQPDLARTAWEESLRYDAPVHFVHRYASEAFVVGGSEVKKGQRLLLGLHAASRDEARFPHADRFVIDRSDNRHLAFAGGGHFCLGSQLSRLEGDVLLRTIFQRFPRMRLTETRLDRVPDLTFPMLLRMTVDLRGSEG
>NZ_CP053618.1|WP_081004668.1|3119059_3120031_-|cupin-domain-containing-protein
MDPITAALDTCRFAEIEAGQAQSSNPWAVHMPGGVWPVSMYVFTGAACSLFMTRSGQRKTLRDKSVCLILRAQEHLVQDSLLTRPNQPVDLRNPAKADRFQTIAFGESPETGVTSTFFVGMAPARGANTSLFDALPDVLLLDFDELPAWLSQATDAIRDELTWQRPGFRAVALRQAELAVLNLIRHYIASHTPTLPAWISLPDHSRVAAALREFHRDISRPWTLEMLADVAGTSRSRLIAAAQRELREGLFSYVTRIRMQEASRLLADTSASVGQIAWQVGYRSEAAFSIAFKRYSGVQPRQFRGGGAGAGTGTPGADTPSKH
>NZ_CP053618.1|WP_020925100.1|3128135_3128462_+|4a-hydroxytetrahydrobiopterin-dehydratase
MSMFPPARIGTDTAVAALSGWQAVAMRDAIEKRFRFPNFNAAFGFMARVAMFAEKLNHHPEWTNVYNRVDVMLTTHDAGGVTELDVRMAQFMDEAAAQMGATAPKAGL
>NZ_CP053618.1|WP_006388841.1|3128518_3128974_-|winged-helix-turn-helix-transcriptional-regulator
MTTPALERFLTYRLHVINKITDRDTNRAYLEDCGIPLGEARCLAAIGRYAPLSVNDLARAANLNKGQASRSAQALAGRGLIEKKDSAADGRGVVLSLTPTGQAQYRRIIDLIARRNQDIFGCLSAEEQRQLGDMLDRLIAHQRERPEAPQD
>NZ_CP053618.1|WP_053500619.1|3128970_3129192_-|hypothetical-protein
MNDDQLDQVYTRMAQALTRVGEARAPLFLSILGLSALARLPDAQAACALLAQAEAACATPVANYPAATADSPT
>NZ_CP053618.1|WP_173010761.1|3129188_3130823_-|FAD-dependent-monooxygenase
MTLPAHVPVLIVGGGPVGLTLAALLAHYGIASLTLEADDGYCDGSRAICISRRSQEILGWIGADAALNATGLPWTGGRSYYRDREVLHFEMPHDPLQRFAPMVNIQQYFVEEYAHQALQRQPGPAALHWSARAVGVRSTADGVQVDVDIAGHRHALRADWLVACDGGRSSVREALGLKLEGMQYEGRYVIVDIEQASHRPVERLAWFDPPSNPGSTLLMHRQPGNVWRVDYQIRDDEDAADAVAPGNVLPRVQSHLDMIGETAPWKPLWISLYNAKCLTLERYRHGRVLFAGDAAHLVPIFGVRGLNSGLDDAGNLAWKLAWVLRGQAPDSLLDSYSDERVHATRQNLAYGAKSTEFMAPPDFGFRLMREAALRLALSDERARPLINPRQSAPISYEGSPLNLADDAAAQPLAAAPGQPAPDLLLADADAVPRYLSACFGQGFVLLACAPDAAMAAGLQRLAAATRQAPCPLVTIVVGGPAPGAWSDPHGHLHERFGAQPGTAWLLRPDGYVMGRWAMPDATALRAALAPYYPMLESSRQETQP
>NZ_CP053618.1|WP_006388844.1|3130958_3131657_-|hypothetical-protein
MFGRSQRAVFKPSVYQPGQRTRRMPRWLVLLLVGIALGAGGVLFLQTNYGPQRLTVEQSEQLHTELSASKLENQRLQSQLEEATQQRDANKSGHEKLTADLADARAKLDTLNKELVLFQDAMPPDPRGGNLGIRSATFKRQPGLLDYQVLVMREERTGAPFKGTLTFSIDGSYSNGRAATVTPEGPALNVDRYDYALGQLKLPDGFTPKVVVLRVMDGNQKQQAMRIYYVRN
>NZ_CP053618.1|WP_054444384.1|3131816_3132503_-|nucleotidyltransferase-family-protein
MRAMILAAGRGERMRPLTDRLPKPLLPVGGKPLIAWHLERLAAAGFRDVVINHAWLGHEIERALADGAAFGLRIRYSPEAAALETAGGIAQALPLLGPDPFLVINGDIWCDWNPAAAPALATALPAGGAWLLMVDNPPQHPLGDFALDRDGRVRADGEPRLTFSGIGVYHPMLFAGVARGTAARLAPLLRQAMEHDHVRGARHTGRWVDVGTPQRLADLDAELGSSPA
>NZ_CP053618.1|WP_104413893.1|3132502_3133543_-|phosphotransferase
MKNDHDPRLEQIRAWLQGLPAALGLAVDTLRPASADASFRRYFRLDAAGRTLIVMDAPPQHEDCRPFLHVDQLLSDAGLNVPAVIEQDLGQGLLLLSDLGEQTYYQRIQDGVDDASLQSMYRDALAALVRLQQARTTGLAHYDSARLADELKLFPEWYVQKHHGATLDDKTAQALEKIFALLSASNGNQPTVLVHRDYHSPNLMVCDQPQYGPNPGVIDFQDALAGPITYDLASLVTDARTTWEEPQQLDWAIRYWEMARAAGLPVDADFAEFHRAYEWMGLQRNLRILGVFARLNHRDGKAHYLAHMPRVNGYVRQVAQRYGVFTPLLRLLDRLDDRQVSVGYTF
>NZ_CP053618.1|WP_053500627.1|3133711_3136105_+|LPS-assembly-protein-LptD
MRKVRWLILSAISVAGAVQAQGSQGSASSATSITAAPELRTSPGLRMHRLPDGNIPAYMEADTIEGDPDSDLTLTGAAQVRRIDGVIKGDRINYRKDTGEVDVQGNARMMRDGTLVTGPNAKFNVDKYSGEVEKPNFWLGATGGFAVADKADIFSKSQMRLHTVTYSGCSCETPSWYIKANTVDIDFDENEGVARNGVLYFKDVPILASPYMTFPVKKERKSGFLMPTYGTTSKGGFDFSLPYYLNLAPNYDATIQPRYFSKRGLQLGGEFRYLGAGYGGSIYGAYLPNDNVSGEDRWMYWWRHQQLFGNGFYADWDVAKVSDNDYFRDISQLGLNQASTTYLPQRARVGWASTYWSAYAQVYKYQTLQDPDALLTPPYDKQPELYLRGARYDWGGFDVDWTSTAVRFSKPLFLGNRNGPNGDRLQTYPTVSYPIVRPGWFVIPKAGVNYTQYQTDWYNGDWLRLNSGTANAGTSFGYPRSQSRTVPIMSLDAGLIFERDTTLFGKDSIQTLEPRLYYLRVPYRDQSKIPVYDTSLSDFSFSQAFEENIYSGGWDRISNANQLTAALTTRWLDASTGFERASLAVAQRLYFADQQVTLPGETPRENVRSDFLVGASAALTDTFSTDVAAQYNPYDNRWSRALLSGRWSPQRLTTVALAYRYQRDPQAGVAYQPQGQNQISLAVQWPFTKRWYGVGRIDYSLRNGPSSTVSGTNDSPRVTQAIAGLEYKGDCCWVGRMVFQRYAVSATDANTALFFQLELTGLGSLGTDPMNLLNRSIPGYSRITPPAPTGTTFERYE
>NZ_CP053618.1|WP_053500629.1|3136101_3137667_+|peptidylprolyl-isomerase
MMRRLHSLRRFSGNALLLAVCAAFSAAHAAEPNGKGARNAPAAQKSAPPAAGEQFVDGIAAVVDKDVITLRELRDASQRIAGELKARGIQVPDDKTLQHQVLQRLIMERVQRHEADRLGIRVDDAQVDQAIATIAGRNKITVAQLRQEIEKSGVNWDSYRKSLKDEIRSDRLRQRAVDSNIVISDAEVDAFLKDQRRNPAFAAAPQQAQPQPQPEAAPEQAAAPAGPMLYAVAQILVRVPEGSSPEQLAALRKKAEDLLARVKRGDDFASLAAASSDGPEALQGGVMGVRPLDGWPDLFAKAIANLQKGQVSGLLQSGNGFHILKVMDRGTAQPAPSRTARAPVPTPAPQPRPQPQAQAPQGPVEVMQTHARHILIKTSTVMSDEQARQRLEQVRQRLVAGDAKFDDMARQYSQDATAPQGGDLGWLNPGETVPPFEAAMNALKPGEISQPIQTPFGWHLIQVEERRQHDATDDLARMKARQTLFERRAQPAFEDWLDQLRAQAYIDNRLEKQDRINQNNR
>NZ_CP053618.1|WP_173010762.1|3137685_3138477_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MSQHQARKRFGQNFLTDESVVESIVRAVNPARGDTVVEIGPGLSALTRPLLERLDHLTAVEIDRDLAARLRKQFEEGRLTVVEADALTVDFSQFGAGLRVVGNLPYNISSPLLFHLMAWADHVRDQHFMLQREVIDRMVAQPGSGDFSRLSVMLQSRYRMHKLFDVPPEAFDPPPKVVSAIVRMVPLPAERLRPVSARAFETVVARAFSQRRKMLRRVLADWAPQVSWEALDIAPTARAEDISVDRYIRLSDALVEAGVLQGG

Crispr_ID: NZ_CP053618_7

• CRISPR_ID: NZ_CP053618_7
• CRISPR_location: 4474339-4474456
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_CP053618_7

Consensus_repeat	Method
GGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGG	CRISPRCasFinder

spacers of NZ_CP053618_7

>7.1|4474375|46|NZ_CP053618|CRISPRCasFinder
GTCTTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAACGCCCCCTCG

CRISPR arrays and Neighbor proteins around NZ_CP053618_7

CRISPR arrays

The CRISPR arrays of NZ_CP053618_7

>merge|NZ_CP053618|7|4474339-4474456|CRISPRCasFinder
GGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGGGTCTTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAACGCCCCCTCGGGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGG

>NZ_CP053618|7|7|4474339-4474456|CRISPRCasFinder
GGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGG	GTCTTTTTTTGCCGCCGGGCCGCCCCAAGGCAAAAACGCCCCCTCG
GGGGGGCAGCGACCCGCGCAGCGGCGGAGCGTGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053618.1|WP_076410237.1|4467099_4467651_+|translation-initiation-factor-IF-3	unknown	unknown	gnl|CDD|234582
NZ_CP053618.1|WP_173010890.1|4478522_4480940_+|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NZ_CP053618.1|WP_024068407.1|4473778_4474213_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_CP053618.1|WP_054441562.1|4482232_4482670_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_006387993.1|4469321_4469591_+|HPr-family-phosphocarrier-protein	unknown	unknown	gnl|CDD|376329
NZ_CP053618.1|WP_006218735.1|4472897_4473236_-|P-II-family-nitrogen-regulator	unknown	unknown	gnl|CDD|366157
NZ_CP053618.1|WP_006387997.1|4476834_4477032_+|50S-ribosomal-protein-L35	unknown	unknown	gnl|CDD|234676
NZ_CP053618.1|WP_006384618.1|4474502_4474754_+|accessory-factor-UbiK-family-protein	unknown	unknown	gnl|CDD|377337
NZ_CP053618.1|WP_006387998.1|4477049_4477409_+|50S-ribosomal-protein-L20	unknown	unknown	gnl|CDD|179959
NZ_CP053618.1|WP_026385253.1|4467814_4468792_+|glutathione-synthase	unknown	unknown	gnl|CDD|235371
NZ_CP053618.1|WP_006388001.1|4480943_4481282_+|integration-host-factor-subunit-alpha	unknown	unknown	gnl|CDD|178961
NZ_CP053618.1|WP_070668769.1|4474839_4476387_+|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl|CDD|223679
NZ_CP053618.1|WP_026385254.1|4469715_4471410_+|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl|CDD|224006
NZ_CP053618.1|WP_173010889.1|4471627_4472866_-|ammonium-transporter	unknown	unknown	gnl|CDD|182630
NZ_CP053618.1|WP_006388002.1|4481339_4481771_+|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|133393
NZ_CP053618.1|WP_054449060.1|4482880_4483039_-|hypothetical-protein	unknown	unknown	unknown
NZ_CP053618.1|WP_006387999.1|4477486_4478509_+|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NZ_CP053618.1|WP_006387992.1|4468809_4469211_+|PTS-mannose-transporter-subunit-IIA	unknown	unknown	gnl|CDD|225446
NZ_CP053618.1|WP_006387988.1|4463869_4464784_+|dTDP-4-dehydrorhamnose-reductase	unknown	unknown	gnl|CDD|367904
NZ_CP053618.1|WP_054474767.1|4465126_4467079_+|threonine--tRNA-ligase	unknown	unknown	gnl|CDD|234752

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_CP053618.1|WP_076410237.1|4467099_4467651_+|translation-initiation-factor-IF-3	gnl|CDD|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	6.16089e-98
NZ_CP053618.1|WP_173010890.1|4478522_4480940_+|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NZ_CP053618.1|WP_024068407.1|4473778_4474213_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	6.44042e-06
NZ_CP053618.1|WP_006387993.1|4469321_4469591_+|HPr-family-phosphocarrier-protein	gnl|CDD|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	1.83273e-32
NZ_CP053618.1|WP_006218735.1|4472897_4473236_-|P-II-family-nitrogen-regulator	gnl|CDD|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	1.56881e-56
NZ_CP053618.1|WP_006387997.1|4476834_4477032_+|50S-ribosomal-protein-L35	gnl|CDD|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	5.92937e-23
NZ_CP053618.1|WP_006384618.1|4474502_4474754_+|accessory-factor-UbiK-family-protein	gnl|CDD|377337	pfam04380, BMFP, Membrane fusogenic activity. BMFP consists of two structural domains, a coiled-coil C-terminal domain via which the protein self-associates as a trimer, and an N-terminal domain disordered at neutral pH but adopting an amphipathic alpha-helical structure in the presence of phospholipid vesicles, high ionic strength, acidic pH or SDS. BMFP interacts with phospholipid vesicles though the predicted amphipathic alpha-helix induced in the N-terminal half of the protein and promotes aggregation and fusion of vesicles in vitro.	1.05315e-18
NZ_CP053618.1|WP_006387998.1|4477049_4477409_+|50S-ribosomal-protein-L20	gnl|CDD|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	5.46719e-63
NZ_CP053618.1|WP_026385253.1|4467814_4468792_+|glutathione-synthase	gnl|CDD|235371	PRK05246, PRK05246, glutathione synthetase; Provisional.	0
NZ_CP053618.1|WP_006388001.1|4480943_4481282_+|integration-host-factor-subunit-alpha	gnl|CDD|178961	PRK00285, ihfA, integration host factor subunit alpha; Reviewed.	9.73249e-63
NZ_CP053618.1|WP_070668769.1|4474839_4476387_+|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl|CDD|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP053618.1|WP_026385254.1|4469715_4471410_+|phosphoenolpyruvate--protein-phosphotransferase	gnl|CDD|224006	COG1080, PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism].	0
NZ_CP053618.1|WP_173010889.1|4471627_4472866_-|ammonium-transporter	gnl|CDD|182630	PRK10666, PRK10666, ammonium transporter AmtB.	0
NZ_CP053618.1|WP_006388002.1|4481339_4481771_+|MerR-family-transcriptional-regulator	gnl|CDD|133393	cd04765, HTH_MlrA-like_sg2, Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators. Putative helix-turn-helix (HTH) MlrA-like transcription regulators (subgroup 2), N-terminal domain. The MlrA protein, also known as YehV, has been shown to control cell-cell aggregation by co-regulating the expression of curli and extracellular matrix production in Escherichia coli and Salmonella typhimurium. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	9.75016e-41
NZ_CP053618.1|WP_006387999.1|4477486_4478509_+|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP053618.1|WP_006387992.1|4468809_4469211_+|PTS-mannose-transporter-subunit-IIA	gnl|CDD|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	5.57584e-23
NZ_CP053618.1|WP_006387988.1|4463869_4464784_+|dTDP-4-dehydrorhamnose-reductase	gnl|CDD|367904	pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhamnose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhamnose, is synthesized by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.	1.2411e-113
NZ_CP053618.1|WP_054474767.1|4465126_4467079_+|threonine--tRNA-ligase	gnl|CDD|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0

Protein sequences

>NZ_CP053618.1|WP_024068407.1|4473778_4474213_+|hypothetical-protein
MMNTQRKTFAVLALAAALAALAGCNKSDEKAAPPAASTTPAPSTTTPGTPPAATTPPATTAPSGSGAPAGATAGLPAECDAYLTQVSACMDKLGASNPAAASFKQQLDAAKTQWATISDKTQLASQCKQSADLFAQSASQMGCK
>NZ_CP053618.1|WP_006218735.1|4472897_4473236_-|P-II-family-nitrogen-regulator
MKLIIAIIKPFKLDEVRVALSGIGVQGLTVTEVKGFGRQKGHTELYRGAEYAVDFLPKLRVEAAVPDHLVDQVIEAIEQAARTGKIGDGKIFAAPLEQVIRIRTGEAGEAAL
>NZ_CP053618.1|WP_173010889.1|4471627_4472866_-|ammonium-transporter
MDKADISWLLVSTLLVLMMAVPGLAMFYGGLVRSKNVLSVLLQVMCTFVLGLVLWFIYGYSLAFTEGNAFFGGLSRAFFSGMFTPADGKYAMSNSLTELLFASFQATFAGITCALIVGSFAERARFSAVLVFTVIWFTFAYIPIAHMVWFASETAPGLLNAKGALDFAGGTVVHINAGVAGLVGAYVVGKRVGYGREAMQPHNLPMTFVGAALLWVGWFGFNAGSALAANENATLVFFNTMIATAGAVLAWLFTEWAIKGKPSMLGAASGAVAGLVGITPAAGLVGPVGALIIGVVAGVVCVWGVNGLKRLLRADDALDVFGVHGVGGIVGALLTGIFNAQALGGPGLAEPGMILGQLWVQLEGVLLTIVWSGVVAWIAYKIANALCGLRVPEDQEREGLDVTSHGESAYHS
>NZ_CP053618.1|WP_026385254.1|4469715_4471410_+|phosphoenolpyruvate--protein-phosphotransferase
MARGYAIGRAVVMGAAALEVAHYRIAPEDVPAESSRLTEALASAQQELRQLADTLPADAPRELGAMLNVHSLLLGDPLLAEQTLALIAERHYNAEWALTTQGQILGQQFDAMEDEYLRERGADVRQVIERVLHVLSGTSAILPDMSHMGGDEALVVVAHDISPADMLRLRGGRFAAFVTDLGGPTSHTAIVARSMGVPAVVAMGNVRELVRDGDMLIIDGAAGAVVVNPSERILQEYRRRQAAYADERAELGLLRDEPSVTLDGIDIVLHANIELPEEAALALASGAHGIGLFRSEFLFMGRPDLPGEEEQYEAYASVVKVMAGRPVTIRTLDIGSDKTLDGEATVATNPALGQRAIRYCLARPEMFATQLRAILRASAHGPVRLLIPMIAHMHEVVATRAAIESARRELDARGQAYAAHMEVGAMVEVPAIAIAIEPFAQALDFLSIGTNDLIQYTLAIDRGDHDVASLYDPLHPAVLRLVAHTINAGERAGKPVAVCGEMAGDSRMTRLLLGLGLTEFSMHPQQLLDVKREVRRAHTNALRVKVASALNRALPVDLDTLDLA
>NZ_CP053618.1|WP_006387993.1|4469321_4469591_+|HPr-family-phosphocarrier-protein
MPNTDIVISNKLGLHARAAAKLTQLASKFSSEIFISRGAQRVNAKSIMGVMMLAAGLGVTVKLEASGSDAEQALSEIETLFDSKFGEQE
>NZ_CP053618.1|WP_006387992.1|4468809_4469211_+|PTS-mannose-transporter-subunit-IIA
MTTGIVIVVHAPLGAAMRECASHVMGNLDGMLAIHDIQPEDLPDDLAPAVLKDILEQDHGGGVLVLTDLIGATPANISKRAVADAQAQGIQCCVLAGLNTPMLLRALTYRNLSLAETREKALAGGVQGVLRVD
>NZ_CP053618.1|WP_026385253.1|4467814_4468792_+|glutathione-synthase
MHVLFVLDPLPLLKAYKDSSVAMMRALVARGHTLSVAMQGDLYIETGTVKAVTTPIELVDGADLHGHDWWRESAPQDLPLADFGAVVMRKDPPFDMEYVYSTHLLEYAQAQGAKVFNGGAAIRNHPEKLAITEISEFTAPTLVTRNMARLKAFHDTHHDVIVKPLDGMGGTGVFRLQPKDPNLNAILETLTDNGARTIMAQRYIPEIVKGDKRILLIGGEPVPYSLARIPLAGETRGNLAAGGRGVAQPLSPRDREIAEAVAPRLAARGLLLVGLDVIGDYVTEVNVTSPTCFVEIAEQTGFDVAGMFVEALEKAVATGAVAAAA
>NZ_CP053618.1|WP_076410237.1|4467099_4467651_+|translation-initiation-factor-IF-3
MATEKANRINGEIRVPEVRLIGLDGEQLGIVKIADAFRLSEQNDVDLVEIAPNAEPPVCRLMDYGKFKYQEQKRQAEARSKQKVIQVKEVKFRPATDEGDYQVKLRNLRRFLEEGDKAKVTLRFRGREMAHQELGMRVLERVRDDLLELAQVEAMPKLEGRQMVMVLAPKKKAAPAGKPESAA
>NZ_CP053618.1|WP_054474767.1|4465126_4467079_+|threonine--tRNA-ligase
MVQITLPDGSQRQYPGPVTVAEVAQSIGAGLAKAALGGRVTFDGADSTLVDTSYRIEGDARLAIVTAKDADGLDMIRHSTAHLLAYAVKELFPDAQVTIGPVIDNGFYYDFSYKRPFTPEDLAAIEKKMAELAKKDEIVTREVWSRDDAVEFFKGIGEKYKAEIIASIPSNEPLSLYREGEFIDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEMLQRIYGTAWATKEEQEAYLHMLEEAERRDHRKIGRELDLFHFQDEAPGLIFWHPKGWALWQQVEQYMRSVYRDNGYQEVKAPQILDISLWKKTGHWDNYRENMFTTESENRVYGLKPMNCPGHVQIFNAGLHSYRELPLRYGEFGQCHRNEPSGSLHGMMRVRGFTQDDGHIFCTEEQLQDECADFTALLQKVYRDFGFTEVLYKVATRPEKRIGSDEVWDTAEQALMESLRRTGCEFEISPGEGAFYGPKVEYTLKDAIGRHWQCGTIQVDFSMPVRLGAEYVDQNDQRRPPVMLHRAILGSLERFIGMLIENHAGAMPPWLAPVQAVVCCISEPSADYAAEITQSLKKQGFRVESDLRGEKITRKIREHSLQKVPYILVVGDKEKQNGTVAVRGLGGLDLGAIAFDDFVARLSEDVSTRRDVNQPDGSAA
>NZ_CP053618.1|WP_006387988.1|4463869_4464784_+|dTDP-4-dehydrorhamnose-reductase
MPKKILVIGRDGQLGFELRRSLAPLGVVTAVGRADCDLTYPLQIARLVRREKPDVIVNAAAFTAVERAQEDGVRAMRINAEAAGELSALAAERGALIVHYSSDYVFDGAKPGAYDERDTPAPLNVYGRSKLAGEQAVRAMNPAHLVFRTSWVYGVFGNSFLKTMLMALRQPETLRVVSDQRGAPTGAAYIADATALVLARYLARPADEAFPFGLYHLAATGDASWHEYACFIAQQARRAGLAVTLTPADIRAVPSDQYPTTARRPLNSRLDSRLLERTFGIRAPHWEDGVTHALAAIADSRNLA
>NZ_CP053618.1|WP_006384618.1|4474502_4474754_+|accessory-factor-UbiK-family-protein
MNNRTQWMEDIQKNISDLIARSPAADVERNVRAMMTQAFSKLDLVTREEFDVQADLLARTRARVDQLSATVEQLESRLAALDK
>NZ_CP053618.1|WP_070668769.1|4474839_4476387_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MTLAVIASRTLSGLHAHAVRVETHLGPGLPSFNVVGLPDTEVRESRERVRAAILNSGFNFPAGRITVNLSPADIPKESGRFDLPIALGLLLAAGQLAPREEGAREGGAGAADAAAPDPLLAGLVLAGELSLTGALVPVSAALVIALSVARESPGATLILPAGSAEQAAWVEGLRVLSARSLADVAAHVAGVCRLPDAIAASWPAAPPAPCLSDVRGQPGARRALEVAAAGGHSLLMVGPPGAGKSMLAARLPGLLPPLARTQALEVAAIAALAGAPDARMGTPPFRAPHHSASPFALVGGGGRPRPGEISLAHHGVLFLDELPEFSRRTLEALREPLETGRVVIARALHTAQFPARFQLVAAMNPCPCGWRGHPRRACQCTPDQVARYAGKVSGPLLDRIDLYVTLPPPDLESLQGPPGEASAPVRARVARCRERQLARQGKSNAGLAGAELERHCPMDPSAQALLLQAMRRLAGSGRALHRALRVARTIADLDGADTLQASHVAQAVQYRRPGV
>NZ_CP053618.1|WP_006387997.1|4476834_4477032_+|50S-ribosomal-protein-L35
MPKMKTKKSAAKRFQVRGSGSIKRGQAFKRHILTKKTTKNKRQLRGSAAVHETNVASVKAMMPFA
>NZ_CP053618.1|WP_006387998.1|4477049_4477409_+|50S-ribosomal-protein-L20
MPRVKRGVTARARHKKVISAAKGYRGRRGNVFRIAKQAVMRAGQYAYRDRRNKKRTFRALWITRINAAVREHGVSYSVFIAGLKKAAIELDRKVLADLAVRDKAGFAAIVQQAKAALAA
>NZ_CP053618.1|WP_006387999.1|4477486_4478509_+|phenylalanine--tRNA-ligase-subunit-alpha
MTQSVDDLVSQAQERFAAATDAAALENAKARFLGKDGALTVLLKGLGKLDPEQKRDMGARINQAKQKVEELLNLRRAALAQAELDARLASETIDVSLPGRGRVPGGIHPVIRTWERVEEIFRSIGFDVADGPEVENDWTNFTALNNPLDHPARSMQDTFYVDMKDADGLPLLLRTHTSPMQVRYARMHKPPIKVIAPGRTYRVDSDATHSPMFHQVEGLWIAEDISFADLKGVYTDFLRCFFESDDLVVRFRPSFFPFTEPSAEIDMMFTSGPNRGRWLEISGSGQVHPQVVRNFGLDPERYIGFAFGSGLERLTMLRYGVNDLRQFYEGDLRFLRQFNE
>NZ_CP053618.1|WP_173010890.1|4478522_4480940_+|phenylalanine--tRNA-ligase-subunit-beta
MQFPESWLRTLVNPPIATDELAHRLTMAGLEVEDTVPAAPAFTGVVVAHIVEIAPHPDADKLRVCQVDDGSGALLQIVCGAPNAAAGLKVPLARVGAELPGGMKIGVAKMRGVQSSGMLCSARELGLSQDHAGLLELPADMAPGQSIREALDLDDTLFTLKMTPNRADCLSILGVAREVAALTGAPLSVPTAKAVPVTLDELRPVRIEAPDLCGRFGGRVIRGVNARAQTPAWMKTRLERAGQRSVSALVDISNYVMLELGRPSHVFDLDKIHGDLSVRWAREGETLELLNGQTVTLDSKVGVVVAGDQVESLAGIMGGEATAVTLDTQNIYLEAAFWWPQSLAGRARRYKFSSEASHRGERGVDFATIPQHIEFITRLIVDICGGQAGPLDDQIVNLPKREPVRMRLARCHRVLGVPVTQAEVAKIFGSLGLEFTLDGDDFVVTPPSYRFDLEIEEDLIEEVARIYGFENIPTLPPLARAKMFSQPEVRRGPHALRRLAAAQDYQEVVNYSFVEAEWERDYAGNDTPVKLVNPIASHLSVMRSSLIAGLVANIRHNANRKQTRVRLFELGRVFARDDAAKDGPLEVAGVRQPLKLAGAAWGPSVEEQWGVPARQVDFYDVKMDVEALFGARGARLRFEAAAHPALHPGRSARISLDGTQVGWLGELHPRWAQQADLAHAPVVFELDVQALSEGELPQVRELSRQPVVVRDLALWVDAPVTVQSMLDTVAATVKADPQLAVVQDVRLFDVWREKPQGDQPVAEKSLAFRFWLQDTEVTLDEARVAACLARIKDALVSAHGARQRA
>NZ_CP053618.1|WP_006388001.1|4480943_4481282_+|integration-host-factor-subunit-alpha
MGNSMLAEPRTLTKAELAELLFERVGLNKREAKDIVDTFFEEIRDALARGDSVKLSGFGNFQVRDKPPRPGRNPKTGETIPIAARRVVTFHASQKLKSVVEQATPAAPDAEE
>NZ_CP053618.1|WP_006388002.1|4481339_4481771_+|MerR-family-transcriptional-regulator
MTRTESTVTLPPIPAKRYFTIGEVSDLCGVKPHVLRYWEQEFTQLKPVKRRGNRRYYQHHEVLLIRRIRSLLYEQGFTISGARNRLGDARDTPHDQDAAVRLSGAEMQALRNELGNVSTMLGEALGSAATASSGNAVSANATA
>NZ_CP053618.1|WP_054441562.1|4482232_4482670_-|hypothetical-protein
MLKSICRIAPAVILPLTLSACMGLSVYSPTRNKLDAQVGKNINEMLPAWPPETGAKPFVNKVDDQTTSYTYVYGYHPGHYEGRGYSTNGPMGATYGSYSAYVPEYTDCAVIFYTDKAGTVLRYDMKTNGKISYNSCGEYISGFRF
>NZ_CP053618.1|WP_054449060.1|4482880_4483039_-|hypothetical-protein
MKWLLISLLCLFCTGCGLAAAPCRVTSAVIKIVPVVGGVAAAPTDACAEVID

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1565831 : 1582879	18	Burkholderia_virus(33.33%)	tail	NA
DBSCAN-SWA_2	4171644 : 4183031	13	Burkholderia_phage(44.44%)	tail,integrase	attL 4166652:4166667|attR 4182530:4182545
DBSCAN-SWA_3	5035629 : 5043565	9	Moraxella_phage(33.33%)	tRNA	NA
DBSCAN-SWA_4	6218792 : 6293539	97	uncultured_Caudovirales_phage(21.21%)	head,portal,protease,integrase,tail,capsid,terminase	attL 6247405:6247436|attR 6295799:6295830

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_CP053618|1565831:1582879|DBSCAN-SWA
CATGACCACGAAGAACCCCATTCCCGGCGATATCGCCGCCCTGCCCGTCGACCTGACCGGCCAGCGCGTGATCGTGACGGCGGGCGCGGCCGGCATCGGCGCGGCCATCGCCGGCGCCTTCGCCGCGCGTGGCGCCCAGGTCCATATCTGCGATGTGGACGAACGCGCGCTGGCGGCCTGCCCGCATCCCTGGTCGCGCGCCGACGTCAGCCAGCGCGACCAGATCGACCGCTACATGCAGGAAGCCTTGGCGCGGCTGGGCGGGCTGGACGTGCTGGTGAACAACGCCGGCATCGCCGGGCCGACAGCCGGTATCGCCGACATTGCGCCGCAGGAGCTGGACGCGACGCTGGACATCAACCTGGCGTCGCAATTCCATACCGTGCGCCACGCGCTGCCGGCCTTGCGCCAGGCCGGCGGCGGCAGCATCATCAATATCAGCTCGGTGGCCGGCCGCATGGGCGTGCCGATGCGCACGCCCTACGCGGCCACGAAATGGGGCGTGGTGGGATTGACGCGATCGCTGGCAGTGGAACTGGGTGGCTACGGCATCCGGGTAAACGCGCTGCTGCCCGGACTGGTGGCGGGGCCGCGGATCGACCGGGTGATCGAGGCGCGCGCCCGCAACATGGGCGTGACGGTGGCCGAGGAAACCCGGCTGGAACTGGCCGGTGTCAGCCTGGGGCAGTTCGTGCGGGCGGCCGACATCGCCAACATGGCGCTGTTCCTGGCCAGCCCGTTCGGCGCGATGGTCAGCGGCCAGGCCATCAGCATCGATGGCGACCTGCAGTCGCTGCCCTGGCAGCCGCCGGCGGATTGACACGCGACCGCCGGCGACTCATGCGAGCAGCTGGATGGTATGCGCATAGACGCCGTGCCGACGATCCTCGGCCGCGGCGCGCAACGCGTCCAGCAGGCGCTCCGCCAGATCCTGGCTGGCGGATTCCTTGCGCGTGATCAGCACGAAATCGAACCACTGGCGCGACGCCAGCGGCAGCGCCACCAGTTCGGGATAGGCCGGCACGATGTCGGCGGCCGACAAGGCGTTGACCATGCTGATGCCGCGCACCGCCCTGACGGTGCCCGGCAGCAGCGACATGTGGGCCTGCATGCCCGAACGCAGTTGCAGCGACTCGGCGATATCGCCTTGCGGCATGACGTAGTCGGACCACAGCGGCTGCACGTAGCTGTCGGGCCGGATGTCGCCGACCGCGACCGCCTCCTGGCGCGCCAGGGGATGGTCGCGATGGACGATGGCCATGACTTCGGTGCGCAGGAATGGCAGGAAGGCAAGGCGGGCGCTATCGCGCGACACGGCGCCAAGGCCGAAATCGGCGCGCATGGTCTCCACGGCGCTGATGACCTGCACCGAGGATTCCAGGTCGATCGAGAACGGCCGGGTGCCGTTGGCATCGAGGTAGCGCCGCACCGCATCGGGCGCGTACGCCAGCGCCAGCGCCGGCGATGCCGCGATCCGCAGGTTGCGGCCACCGAATTGCTCGATACTGTGCAATGCCTCATCGATGCGGACCAGCTCGTCCAGGACGTGCTTGGCCTCGCTGTAGAGATACTGCCCGGCTTCGGTCGGGCGCAGAGTCTTGTGGGACCGGTCGAACAACTGCACGCCGGTGGCCTGTTCCAGGCGCGAGATCGCGTGGCTGACGGCCGGCTGCGTCAGGTGCATGGCCTGCGCGGCCTGGCGGGTGGATCCGGTCATGACCACCGTGTAGAAAATGCGCAGGTCGTGGATATTGAAGTTGCGCTTCATGCGGCGTCGCGGCTCCCCCGATTGGATATGGCCGGCGCGGCCCTGCTCGCGCCGGTTCCTGATTCTAGGTCGAGTCGGCGTCAAAAGCAGGCAGAGCGGATGGGAACCGCGTCCGACATGGGGACGGCCGCCCGCCGCTTCTCACACCTGGTCCTCCGAGTAGATCCCCGCCGAGATGGTGGCGCTGCCGACGAACAGCTCGCCGTACAGCACCGGCACCGGATTGCCCTGCGCGGTGGTGTTGACCGGACCATTGAAGTTGTAGGACGCGCCATTGTTCGGGCCGTCCTTGACGCTCAGGGCGCGCTGCTGCGGCGTCAGCAGCTGGACCACGCCGCCCAGGGTCATGGCCACCCCCATGGTCATCAGCGACGTGCTGGCGCCCGCCCACAGCGCCACGTTGACGCCGGGGATGAAGGACGCCACGATCATCGCCACGCCCACCACCACCTGCATCAGGCCGCCCCGCTTGGCGCCGGTGGGCATGGGCGCGATGCGGATGTCCTCGTTGCCGGCGGGTCGGCCGAGCTCCGCTTCGGCCAGGTTGCGGCGGCCGATGAAGCAGGCGTAGCGCACGCCCCGGGATTCGCTGTCGAGCAGGCGGGTTTCAAAGCCGGGCAGCAGCGCGCACAGGGCGCGCACCGCTTCCGCGGTGCTGGAGACGGCCAGCCGATGCAGCCGGCCGAATTCCGCGCCCAGCCTGCCATAGAGGCGGATGGTTGTCAGGGATTGGGTCATGTCGGATTCCTCGCGAGGTCCGCGCCGCCCCCGGCATCGACGCTGGCGGGTTTCGGGTAGCGTTGCTTGACGCCCTGGCATTGCGCCACCCATTGCGCCACCGGCTCGGGCAAGGCCTGCCCCGAGGATTGCAGGTGCGCGGCGAACTTCATGATCGCGTCGAGCTGGTCGCCGATGGCGGGATAGGCGCGCGCGCGCAGCGGCGCGTAGGGTTCATAGTGGCGGATTTTCAACGGTGAACTCCTTGTTCAGATAGGGCCAGGCTTCGACGGTGACGTGGTAAGTCCCCGGCTGATCGAATGCGAGCTCGGCGGTGGTGTCGTTGCAGGGGTATGCGCGGTCACCGATCTTGATGGTGCAAGGGATCGGGAGCGCCGAAAGGGTATGCCGCGCCAGGATGGCGGGGGATTCCGGCCGGGAAACGAGGGCGTTTTCCCGTACATACTGGGACTCCGGGTTTCCCTCCCCGTCGACAAAGGGATGGCCGGTAACCTGCGCCGTGGCGTCCACGCTCTCGCGCGGCCCGCGCATGACACCGATGATCCGGCCCGTCGGATCGTAGAACGATGCGGTATGCATGTTCATGCTTCTCACCTCTTCACCATGAGTGCAACGATACGGATCGTCGCCTGATTGCTTTCTGAACTCGACGAGTTGACTGTTATCGTCGTATTTCCCACCCCGGCGTTGCCCACCGCCACCGCGGTCAAAGGCAGACTCGTGTACTCCAAGGGCTGGGTACCTTCCCCACTGCCGCTCTGCCATACGGTATGCGAGCCCGCCGCCGCCTCCACCAACGCGCCGTTCACGTAGATCCGCAAAGTCGACGCGCGCCCGGCATAGCCGGACCGGTATGCAATCACGACGACCGGTCCCGCCACATTGCTGTTGATGACGACGGTTCCTGCGGTATTTCCCGCCCACGACGTGGGAATCGTCACCGCGTTGCCCGCGATCGACAGCGTATCGACCTGCGCATCACGGATATGCGCCCGCGAGATGTACGCCGTACCCAGGTTCGCCAGCTTGGCCGTCAACGCATTCGCCTCCAGGCGATCCACGTTGATATACCCCGCGTCGATCTTGCCCGCATCCAGGCTGCGGATCATCGCGTTGGTGATGCGCCCGGTGCCGATCACCGCGTCATTGATGAAGGTCTGCCCGTTCTCGATGACGAACGGCGTGGTGGTCGCGCCGTTGGCCAGGTTCAGCAGGGCCAGCCGGTCCGCCAGGAAGTACACCGAGGTCTGCACCTGGCCGTCGGGCTGGGTGTAGGCGCCCAGCGACATGCCGGCGGCGTAGACCTTGTTGTCCTGCGTGACCTGGGCTTTTACGCTCCAGGTGGCCTTGAGCTTGCCGTCCAGCCCGACCAGCGCCGTGCGCGCCTGCTCGACACCCGCGGCGGCGCCGTTGGCGGTCGCCAGCACGGTGTCGACGCGCGAGGACAACGCCCCGTCCGCGTCGGCCCGCTTGGTCTCCTCGGCGGTGATGGCCGCGCGCGTTTCGTCCAGGCCGGTCGTCAGGCCGTCGATGGTGCCGACGAGATCCTTGGCCAGTTCGTCGCGGCTGATCTTGCCGTTCAGGTACTCCAGGATCTCGCTGGCTTCCCAGCTGGATTCGCCCATCACGCCCTGGTCGGCCGGATACCAGGCGCCGATCTCGCCGTTCAGGGCGACGATGCGGCCCCAGAAGTAGAAGCGCTTGCCGGCCGACAGGCCCATCAGCGTATGCGCGCTTTGCGGGAAGGCGAAGTCGCCCAGCTTGATGGCGCTGGCGCGGTCGTTGGAGGCGCTGTACCAGATCTCGGTGCGCTGCGCGGTGAAGCGGCCTTCCGGGAAGGCCCAGCGCAGCTCAATGCCGAAAACCAGGGATTTGGCGGCCAGCAGGGCCAGCGCGGGCGGCGGCGCGATATCTCCCTCCAGCGTCGTTTCGGTCGAATTGACCCACACCGACGAGATGTCCGACACGTTGATGGCACGCACCCGAGCCACATAGGCGCCGGCCCGGATATCCGGCAGTTCCAGCGTCAATGCGCCCGTGCGGCCCGCCTCGACCCAGTCGGAATTGTCCCGTCGCCATTGCACCTGGTAGGCCACGGCCGAGGGCGCCGCATCCCAGCTGATGATGCCCACATGGCGCGCGATGCCCTGGTCGATCACCGAGCGCGACGCCAGGCGGATGTAGCCCGGCGCCGGTTGCACCGAGGGCGGCACCACCGTGATCGGCTTGGGATCCAGCCGGGTGCCGAAGTCCACGTTGTCGAACTTGCCGGGTTCGTGCTGGACCGCCGAGATCTCGGCCACCAGCCCTTCCTTGCGCTTGACGCTCAGCACGCGGAAGGTCTGCGCCGACAGGGCTTCGGATTCCAGGGTCCAGACGCATTCGGCCTCCGGGGCCTGCGAGAACGGCGTGGTCACCGTGATGTGCAGCACGGTGCCGGGCAGGCCGACCAGGTCGGCCGTCAGCTCGGTGGAATCCACCGTGAAGGCGACGTTGTCCACCGTCAGGCCGGTGCCCACCGCGGCCGCCACCACGCGCGTTTCCGACAGGCCATTGGGCAGGTTGACGGTCAGGCGGTCGCCCGGGCGCACCCCCAGCTCCGCGTCCACCGTGACCTTGCTGACGGTGCCTTCGCGGATGCGGCCGCCGATGCGCCGTCCCGCCAGATGCTGATCCGCCACGCGGATGACACTGCCGGGACGCACGCGGCAGGCGTCCAGGCCCACCGAGAACGTGACCGAACGCGTTTCCAGGTTGGACGTCAGCAGCATCCACTTGCCGATCCGGTGCGCCTGGCCCCGCGAGGTGCAGCCAAAGCCGGTCACCTCGACCTGCTGGATGCCGTAGCGCGCGATGCCTTCACGGTTCTCGACGTACTCGACCTTCTGGCGGCCCATCTCGGACATATCGCTCCAGGAGACCAATGCCACGGTGTAGCGCGTGGTCAACGCCGAGCCGGCGTAGCTGAACCTGCCATCGACCACGTTGGCCGACGAGAAGGTGTAGACCGGATCGCCCGGCATGTCGGCGGACGCGAACACGGCGGCATTGGCCCAATAGGCCATGCCGCGGAAGATGGAAGCGAAGTCCTGCACCACGCGATAGGCATCGGCCGCCTGCTGCAGGTAGACGTTGCAGGTGAAGCGCGGTTCCTTGCCGCCGAAACCATCGTCGACCATCTCGTCGCAATAGCGGCCGATCTGGTACAGGCCCCACTTGTCCAGCCAGCCCGCCGGCACGCGGGTTCCCAGGCCATAGCGGTCGTTGCTGACCAGGTCGTAGAAGATCCAGGCGGGGTTGTTGGTCCAGGCCAGCTTGAAGGTGCCGTCCCATACGCCGTCGTAGCTGCGCAGATCCGGGTGATAGTTGGACGGCACGCGGATGATGCGGCCGCGCACGTGGTAAGCCCGGGTGGGAATGCTCTGGAACTGCGACGCGTCGATCTTGATGCCCACCAGCGCGGACATCGGATAGCGCAGCTTGGCATCGATGATCTCGGTGACCGTGTCCACCACGGTGCGGTCGGAGATGGTATTGCTGTTGGCATTGGGCGTGATCCGGCGCACGCGCAGGGTCCAGCCCTGGCGCGCGCGCGGCAGGTCGATGCGATGCGAGCGGGTGTAGCGCTGCGTGGTCTTGCCGTCGAAGGCGGTCGACAGCACCACCTGGTAGCCGGCGCCATCGGTGTTCAGCTCGATCACGTACTCGACGCGGTAGCCGTTGATGTCGCCATTCTTGGTGTCGGCGCGGCTCAGTCCTTCCACGGCCAGCGTCACGCGCACCGCCGACGCCTGCAGATTGGTGAACAGGCGCGTCCACGGCTGGCTCGACTTGAGCTCGGCATTGATGCCGATGGTGCTTTCCGAGGCGGGAAAACCGGGCAGCGGATCCTGCCACTGCGTGCCGGTGCGAAAGTCGATCGACGCGCCGCTGAAGTTCAACGAGCCGTCCTCGTTGGCCACGGGCGTGCCGTTCAGGTAGACGTCGCGCAGCGCGTTGTCCATGCCGTGCACCGGGCCGTAGATCTCGCCTTCGCCCAGCAGGTCGATGACGCGCGCATAGGCGGTGCTGTGCAGGCTGTCGGGAGATTCCACGGGCGTGCGTCCCCCGCCGCCGCCCTTGCCCTTGTGGCCAACCAGCGCCGGATTCCCGGCGTGGCGCCCGCCCCCCAAAGCAAAGGCGCCCGCGGGCGCCTTGTTCCTGTTGCGATGTCGTTGTTTCATACGTGGTCTTCCGAATAGATGCCTGCGGAGATCGTGGCGCTGCCGACGAACATTTCCCCATACAGCAAAGGCACGGGGTTTCCCTGCGCAGTGGTGTTCACGGGTCCGTTGAAGTTATAGGACGCGCCGTTGTCGGGCCGGTCCTTGGCGCTGAGCAGCCGCTGCTGGGGCGACAGCATCTGGGCCACGCCGCTCAGCATCATGGACAATCCCATGGTGGCCGTGGCCTGCACCATCCCCCCTGCCTGGAACGCGGCCGCCACGCCACCGCTGTAGATCGCCGCGGCGGCGATCAGCACCGCGCCCAGCATGGTCTGGAACAGCCCGCCGTTCTTGGCGCCCGCCAGCATCGGCGCGATGCGGATGACATCCGCGCCCACCGGGTGCCGCAACTCGTCTTGCGACAGATTGCGGCGACCGGCGAAGCAGGCGAAGCGCACCCCGCGTCGTTCACTGGCCAGCAAGGCCGGCTCGAAGCCGGGCAACAGGGCACACAACGCCCGCACCGCCTCGGCCGGGCTGGCCACAGCCAGGCGATGTTCGCGGCCAAAACGCTTGCCCAGCCAGCCATACAGGCGGACCAGGCGTACCTTGTCGTTCATGTCCTTTCTCCATAACGCAGCACCAGGCGGGTGGCTTCGCGCCAGAAACCGCCGTACACGACCCGTTCGGAGTCACGTCCATACAGGTGATGCAACATTGCGTCGGGCAGCGGGAACAGGTCCGGCGCCTCGCGCAGCGGCTCCGGGCCGATGAAGACGCCGGCGTGGTTGGCGCGGTCCGACCGCACCTGCATCACCACAACGTCGCCGGGCGCCATGGTTTCGTGCGGCGCCAGCGGCCGGAATCCCGCCTCGGCGTAGTGATCCATGTACAGATCGCCCGCATGGCCCGGCTGCCACCAGCCGTCTTCGCGGGCGAAATCCGGCAGCCGGATCCCGCGTTCGCGCGCATACCAGTCGCGCACCAGCGAATAGCAATCGAGCACGCCATGCGCGAACTGGCGGCCCAGCAGCGGCGCCTGGAAGCCTTCGGGCGTGAAGCCGCGGATCTCTCCCGCCTTGACCTTTCCATCCAGGTCCTTCTCCACCGCCACGATGTACCAGGGCAGGCCGGACGCCTCGCAGGCCACCCGGTCGGCCTCGCTGGGCACGGCGGGCGCGTCCGGATGCGAATGCACCACCGCCACGATCCGGCCGCTTTCCTCGGCCGCCGCGTAGTCCTGCGCCGACATGACGAAGTGCTCTTCACTGGCGGCCGTATTGCGGCACGGCACATACCATTCACGGCGGCCGGCCTTGAGCACCAGGCCGCAGCATTCCTGCGGATACGTCGCCACGCCATGGTCGCGGATGGCTTGCATCGTGCGCTTGAGCATGCCTATCCCCTTACCAGGTCGGCGGACGGGAAGCCGCCGAAGTTGATGACTTCGTACTCGCCGAAGCGCTTCTTGCAGTCGGACATCAACCCCGAGCAGCGGTCCAGCGTGGGATCGGTGACCGGCTTGCCGTCCAGGTCGAACATGCGGCTGCCGGTATAGCCGCAATAGGGGCCGCGATAGCCGCCCTTGCGCAGCCACGAACACACGCCGGCGATGATCGGGCGGTCGGGCAGCTTCTGGCCGTTGAAGTCCAGGGCGCTGGAGAGCGAGAACTCCACCACCTGCGCGGTCTCCACGGTCTTCTGCTGCACGATCCAGACTTCGGGCGGCAGTTCTTCCTGCGGATCGGCAGTGGGGTTGCCTTCGGCAAAGTTCACCGCGTCCAGGTATTTGCCCAGCGTGCGGCGCACGACCACGCGCGCGCCCACCAGGTCATCCAGGTGGATGCAGAGGGCGGAGATGACGCCGGGCAGAGGGTCGCCTTTTTCGTCCTGGCCGATGTTGCCCACCCGCAACGTGGGCGAAGGCTGCTGGCCCTCGCCCACCTGCTCGAAGCCCTCGGCCTGGATCGACCACGGATCGTATTGCTTGCCCTGCCAGTGGATGGCCCCGACCTGCATGTAGCCATGGAAGCGCTGTACGGCGCCGCCGATCTCGCTGGCATCCAGCTCGAACAACTCGACCAGCGCGCCGGGCTCCAGTTTCTGTATATCTGCGGTTATCGGCATTCCTATGCCTCCATTTTCGTGAGCGCTTTCACACGTTCTTCGAGCGCATTGATCCGCATGTCGGCATGCTGAAGCGCGGCAATCAGGTCCGGGACGATCTTGGAGTAATCCACCTGCTGGTAGGCGGGAACGGACTCCTCCATGCCCGGCATCTTGATCATTTCGTCCTTGATGCCGGTCACCGCATGAGGAATGAGCGCCTGCAATTCGTGGGCGATCGCGCCGCGGTACCGGATGCCGGCATCGGCCATGCTGTAATCTACGACCCGCACGCCCATGACGCGGCTGTAGCTTTCGGCGATCGGCGTTGCGGCGACATCATGTTTGAGTCGATAGTCGGACGCCGTGTTGTATTGCGTGATCGAGTCGGTGACCTGAATCGACCCCACAAGGCTATTGGCGCTGTTCATGAAGCCCACCGCCACCGTGGTGCCCGCGTTGCGGGGCTTGAATATCAAGCCGTACTCATAATTGGCGCCCAGGTAATTGATCGTCGCGATGTGGGTATACGGCGGCGGCGTCAGCAGATCCGGGCCGAAAACCCAGCGCGACCCGATGATGCGGCCGCGTTCGATATCATCGGTAATGAATCTGACGGGCATGGGACCTCCCCACCCGTTTTTCGTCGTCCCCAACGTGGCCACCCCGGTGCCGCAGGCCATGATCATGGTGGGGGAATTGGGATCGGCGTACGGCGTGGCCCGGAAGATCGCGCCCTTGCCATTGTTGCCGGCCACGGTGAAATAGCAGTTCTCGTCTATCAACGAACGGATCAACGGCCCATTGGCATAGTCCTGCGTGCTGCGGTCCTGCCATATATGAGCGACAGGCGGAGAGAACCGTACATAGCCGCCTTGCGCCTGCGACCAGCGACGCCATCCGGCGCCTTCGAACCAGACGTCGCCACAATCCTCGCTCGCGAGATCGGCGGCATCCGAAATGGCTCCGACGTATCGCCATCGCGTCCATCCCCCCGTAGCGGTTCCGTCGCCCGCGGGGACGAACTGCCTGGAGAATTCCGGTCCGCTCGCGTCCGCTTTCAGGGCGCCGTAGCGCAGACGTTGCATCACCACGCCGGACAGATCGAGGACACTCACCTCGCCACATTGGCGCAGGGCCTGCAACTTGGGATAGTTGGCGCCATTCTCGAGCGTGTAGGCAGTGCGCCACAGGAAAGCGCCAGAGGACTTCATCGAATTGAAATCCACACCGGTTCCCGTGATGTCCTGCACCGTTCCCGCCTCGCGCCAAGGAGTCCAGGCGTTCTGCGACAGAAGGGTACGAAAATACAACCGGGGTGAAGCTTCGCGCGAACTGAGCGTCTGGACCGCCGCGTCGCCCGCCGCTTCGACCAGCAGGAAGGCGGGGGCATTCAATCCGGCAGGAAGATTCGACACGCCCGCGGACGAGGACAGGAAAACCTCCACTGGCCGCTTGTACTCGTTCAAATCGACGTTGCCTTGGACGACCACACACTTGCGCTTGGGACGATACTCATCCGGCACGGCACCATCGGCACCGAGGGGCGCCACCCCTTCCGGTTTGCCTTTGTCGCTGCGAGGAAGCGCGGCGTCCGCCGTACCCTGCGCCCGATCCGCCGCATCGGCGGCGGCCTGCGCGGACCGCTGCGCTTGCGATGCCGCGGCGCCCGCGGAATCTGCGCTGGCCTGGGCATGCAGGGCCTTGGCGTCCGCTTCATCGGCGGCCTGTCGCGCTTGCCTGGCAGCCGCGTCGGCCGTATCCCCGGTTCGCTGGGCCGCCACAGCCTTGCCATCGGCGACATCAGCGGCCTTGCCAGCGTCCGCGGCTTTCAATTCGGCGATCGCGGCCGCCGTTGCATTGGCGACCGTACGCCGGTCCAGTTCAGCGATATTCGCGTTGACCTTATCGAATGCGGATCGCAGTTGATCGCCGGTTTGGTCGTTGGGCGCCGCGCCAATGTTGATCTGCTTTATTGCCGTCATGGTTTGAACACCTGATCCATCGTGAACGACAAGGCGAACATGTCGCCCTCCATGGCGCGCAAGCGCACTTCGCGCGCCTTGTAGTACCCCTGCTCCCCCATCGGCGGTGTCCAGAAGAAAGCGCGGTAGCCCGCATGGCGCTTTACGAATTCGAGAATGGGCCGGACATACGCCTCCCTGCCGACGAACTCCAGCGGCCAGGATTGGGTCGCCGCATGAATGCCATCGGCCGCTTCCTGCTCGTAGCCGTCGCCGAACTGCACGCGCAGGGTCCGGTCCTTGAGCGTGCCGACGGGATTGGGCCGAGGCGACCAGTTGAAGACTTCGATTGCCATGCTCATGCCCCCGCTAAACGGTTGTTGTTGGCTTGCCACGCCAGGCCACCCTGGCGATACGATTGCGACATGCGGCGATCGACCAGTTGCGTGACGTATTCGCCGATCTGCTGGCCGAACTGCTGCCAGCCGCCCTCCCCGGATTCGCTGGAGGCACTGACGTTGCCGTCCTGCACGTAGACGTTGACGGCAACGCCGCCCGCGACGGGGTTGGTATCGCCGCCAACACTCGGGAAGGCCGCGCGAATGCCGAGCGAACCGTCGGCGCCGCGATGCAGCGGCATGATGGCCTCGGGCCCGGCCTCGCCCATGACGCCCATGGGGAAGGCGACGGGACTCGTGACCATGCCGTTGGTGAAGGCGTTGCCCTTGGCGCTGGGGAAGAATGACAGCGCCGTTCCGCCGGAGACGAAGCTGCTGCCAACGGAAATCCCCCCGCCGCCGCTGAAGAGGTCTGAGAGGAACGATCCGGCTTTCCCGATCCATCCCCCCACGCCGCCCTTGCCCTCCATGAAGCTATTGCCCAGCAGGGTTTCCATCAATTTGGCGGACGCCGCCGAGGTCACCATCTTTGCCACGTTGTTCAGGAACGACAGGCCCAGCTTGTCGAACTTGTCCGCGACAAAGTCGTACATCTTCGTGCCCAGGATGTCCTGGATCTTGCTTGCGCCGTTGCGCGCCGATTCGAGCAGCTTGTCGTTCACGTCCAGCATGAAATCGCCGTCCCGCTTGACCAGACCGAGACCGCGTCTTGCCGTGTCGTACTTGTCCTGGCTCAGCGTGCCATCGCTCAAGGCCTGATCGAGCGCCTCCTGCTTTTGACGCTTTTCTTCGTTGGCGGCCGCGTCGGGATTCGCCAGGCTCTGGATATACGCGCTCATCTTCATCTGCGCGCGCAACTTGTCCAACCGCGACGCGCCAGCCAGCAAGCTGACCTTGTCGTCATCGCTCTCGCCCGAGAATCTGCCGATCTCGGTTTCCACCCGCATTCGTCCAACTTCCGAGTCCACGCCCAGCAGCGCGCCGGTCTTGCGCATGTCCGCCAGTGTCTGCTCGACGGCTTCCGACCGGATAGCGCGGGCGTTCCGATCCAGCGCCTGCGTCGCCTTGGCCTTTTCAGCCGTTCCCAACCTGGTGACGGCGGTGTTCTTGGCGCCTGCCGTCGCGGTCTTCGCGAGTTCGCTGCCGCGCGCCTTCAGCGCCGTGCAATTCCGGTTGAGTTCGGTGGTCTGCTGCTTCAACGCCGCAGTTTCCGCGGCGATCTGCGCCGCGGTCTGTATGGTTGTCATGGTCCTTTACCTCTCATAGATCCGCCTCCGGCCCGCTTGCGCGGGCCGGACACGTCGTCAAGACCCCTTCCCGGCCTTCGACAGCAGGAACGCCTTCAACGCGTCCGCCCCCGCCTCGGCGGGAGGTTCCTCGTCGTGCGCGCCCCAACGCACCAGCATGTCCGTGGCGCGCACCTTGGCGCCGGCGGCCTGCGCCACCGTGGCGGCGAGGCTGGCGGCAAGCAGGTCGGCCCGCTCGTCTCCCAGGGGAGAGGTGCGGTCCAGTTCGCGCCACAAGGACAATTCATGGGTGTCGATGCTGTCCATCAACTCGCCCAGCGTGCGTCCCAGCCGAAGGGCCAGGACCATCAGGAAACGGAGGTCTGGCGTTTCCTGGAGGGCTTTTTTGCGCGCTCCTGCGCACCCTCCCCGAGGTTGCCCAGCTCGATTGCCCTGGCCACCAGCGTGGCGTGGGCCGGCCCGTAGGCCGCCGCCACCATGTCGACGTCGTCATCGCTGAAGACGCGCCGCGGGCCATGCTCGGTCTGCTCGAACAGCGTGCGCACCAGCAGGCTGGCCGAGGCGCGGGTGTAGTCCACGCCCGGCGCGTCCAGCTTGGCGCGCACGGTCTCGTTGTCCTCGCCCGGCACCACGCCCGCGGCTGCCCAGATGGCGCGGATGTGAAACAGGTGATCCCCGGCGCTGGGCGCGCGCACGATGACGCGGGCGTCCTGCCATTGCGGCACGGTGAGGGTTTCATGCGCGAAGCCGGCCAGCGGATCGGCCGCCAGGCCGCGCACGCCCGCCGCGCGAGCCGGGGAATTGATCGACGTGTCCGTCATGGCGCTCAGCCCCCGTTGGCGGGTGCGTCGGTCATCTTGACGGCGCCGGTCACGCGCACGTTGAACGTGGCGGACACGACGTTGTCCAGCTGGCCTTGCCACTGGTATTGCGTCACCAGGCCGAGGAACTCGAACTTGGCGCCGTCGGCGAAGGTCACGCGGAAGGCGCGGGTCTTCTTGTCGCTGCGCGCGGCCACCAGCGCCTTCTGCGCCGGGTCGCCGGCCTTCCAGTTGCCGGCCATGCTGAAGGTGCCGCTGTCGTCCAGGCCCAGGGCGTATTCCTTGGCGGTCGACTTGAGCACGGTGACGTCGATCTCGGTGGTCTGGCCGCCCTGGAAGTTCGGGTCCTTGATGGTGATGGCCAGATCGGCATAAGCCAGGCCAGCCGCGCCCAGGTCCTCGGTGGCCGTGGTCGACACTTCCAGTTGCGTGCCCTGGGTTTGAACGAATTGCGAAACGGTAGTACCTGCCATTGCAGACTCCAAAAAAAAGCCCGCCAATGGCGGGCAATTGCGGACGCCCGGCAAACCGGGGCGGCCACGAAAAAGCCCCGCGGCGAATGCCGCGGGGCTGGATCGGTCTGTCGGGAACGGCATGGCGAACCACGCGGCATGCGTGTTGCGCGATGCCCGTTCCGACGGCTCTCATAAAAAAACCCGCTGGCGCCTTTGGGCGTTCAGCGGGTCTGCGTGGTTCGGGCGCAACTTGCCCCGACGAATCAATTATGCGGAAGCACCGCGCGCGCCGCAAGGTTTGGCGCGATCCGCGTGTCGCACCTGCGGCGCCGTCACCAGCGCGCGGCGGCGCAGCGCGGGCAGCAATGCGGCCTTGGCCTCCTGGTAGGCGGCGTGCTGCTGCTCGGGCGTCAACCGCGGGTTGCTGAAGACGCGCGCGCCGGCCGCCTTGTTGCCGGCATGCACGCCGATCGCCGAGCGCTGCTGCCACGGCAGCTCGTCAATACACAATTCGGTCTGCTCGCCGCGCGTGGCGGCCAGGCGCGCGTCGACATCCTCGTCGTCATAGGCTTCGTCGGACGTCATGCCGCGCGCGAACGCCGCCACCCTGCCCACGCCCAGGTGCGGCCGATAGCCGCGGCTCCAGTGATACCACTCCATGATCAGCGCTTCGACCTGATCCGATTCCTCTCGTGTCATGTTCTGCCCCTTCTGGTGCTGGCCGCGCGCGCCCTCCTGGCGGCTGGCGGCCGCCGCTGCCGGCCGCGCGGAAAGCGAGCGCGCGATGGCCGCGCCCGCCTGCGATGCCGCGGCGATCCAGTCTTGCGGCGCCCGCAGCGCCATGTTTCCTGCCTGATTCATTTGCCGCTCCTTGGCGTTGGGTTCGATGGTGGCGCCCGTCGTCAACACGAGGGGCCGGATGGGTGCCGTGGCGGCACCGCGACGTTGGACGGGCGATGCCGCCGTCCGGATGGGTTGCCGGGAGAAGCGATCAAGTAGCGATACGCTACCCACGCTTCCGTCTGATAACAACACACGTTTCAGGTGATCCATGAGTAGAATTCTACAAATGTATAATCGTCATTTCAACACTTGTTGTTGCACAATTTTCCACAACTGTTTAGCGTCCCATCATGGCTCTCGGAAAACAAATCAGGCACTATCGCGCCGCGCTCGGCCTCACCCTCGAACAACTCGAAGCGCGCACCGGTGTGGGCGTGGGCACCATCGCCGCCCTTGAAGGGCGCGACAGCGAACGCTCCAAGTACGCCTCGCGCCTGGCGGCGGGGCTGGGGCTGACGCTGGAACAACTGCTGGACGAAACCGCGCAATATCCGCCGGACGTCGTGCTGGCCGATACCGGCGGGGCGTCGCGCGCGGACGACGGCGCGGCTGGCGACCTGCGCATTCCGCGCTTCGACACGGGCGGCGCCATGGGCGCGGGGGTGGAACTGCGCGACCAGCCTGGCGTGATCCAGAGCCTGCGCGTCAGCCAGGAATGGCTGCACAAGAACCTGCGGCACTACACCGCGGCCGCCAACCTGTGCGTGGTGACCGGTTTTGGCGACAGCATGCGGCCCATGTACAACCCCGGCGATCCCCTGCTGGTGGACCTGGGCGTGGTCAAGGCCGACGTGGATGGCGTGTTCTTCTTTCGCGTCGGCAACGAAGGCTTCATCAAGCGCCTGCAACGCATTCCCAGCGCCCGCGGCCTGCTGATCCGCGCGAAATCCGAGAACACCAAATACGATGCCTGGGACATCACCGAAGACATGGACCTGCAGATTTTCGGGCGCGTGCTGAAGGTCTGGCGCAGCGAGGATCTGTGACGCGCCGCCCGCACGTGCGGCCCGCGAGCCGCGCAGCGGCGCGTCGGCGCGCCCTGCGCCTTATGAACCGGCGCGCTGCACCTGCGACGTTTGCCAGCTGCCGTCCAGCAACCCTGGCTTGGGCCAGTAGTAGCGCAAGGCCAGCATGAAGGGGCCGGCCGGCGCCGGCAACCAGTTGGCCTGGCCGCCCTTGGCCGGCGCCTGATGCTGGATGCGCAGCGTCAGTCCGCCATCGCGATCGCGCTTGAGCGCGGGCAACATCGTCGAATCGATCACGTAGCGCTGGATGGGGTTGGCCACGACCGATTGCCCCGGCAGCCGGTAGAGCGTGACCGACCAGAAGGCGTTGACCGGCGGCAGGGCGCGCGGCGCGAACCGCAGCGTGTAGGCCTGGGTGCCATCCAGCGGCAGGCCCGCCATGTCGGTGGCCAGCACCGTCGACAGCGATTCTTCGCGGCTGTCGGTGCCCAGGCCGACCTGGGCGCCCGTGGCGCGCGCCAGGTAGTCATTGCGCAATGTCCGGCGATCGCCGAACAAGGTATCGGTCCGGCCGGCCAGCGCCACGCGATGCTTGTCGATGTCGTTCTGGCCGTCATGCATGCCCTCCTGCATGACCTGCCGCAGGCGCGGCGGCATGGCGTCGGTCACCGCTTGCGCGTCCGGGCGGATGCGCAGGCTGTCCAGGCGCTTGCGCAAGGTCTTTTCGCTGTGCGCCACCGGCGCGAATTGCAGCAGGAAGCCCAGCTGGTTGTAGAACTCGAGCGAACTGCGCATCTGCGTGGGCGGCTCGGGCTTGATCCACTGCACCGCGGCAGGCGCTGGTGGCGCGGCCTTCTTCAGGTAGGCGGACAGCGGCTGGATCCGGTAGCCGGCCTGGATGCGCTTGACGTTGGCGATGTCCGACTGCGCGAATCGCTGGGTCCGGCCGCTGACACTGACCAGGTCGGTCTCGGCCCGGATCACCTGGGCGAATCCCTTCGGCGGGGCGCCCTTCCAGCGCGGGCCGGCCACCAGGAACCGACCGCCGCCGTTGCCGGTGGCACGACTGCCGATGTAGGCAAAGTTGTAGCCATACAGGTCCGTCAGCTGCAACGCGAAATAGCGCCTGGACTCCATCGGCGGCACGCTGATGACGACCGGTTCGGCCCGCAGGTCGAGCACGGCCGAGGACGCGGGCGCATCGACATTGGGCGCGGCGGTCGCGTTGTCGTCGGGCGTGACGGCCGGCGCGGCGTGGCTGAAGGTATTGAACGGGCCTTTGTATTGCGCGCCGCCCTGGTCGATGTTCGTGGAATAGATGGCCTGGTAGCGGGCCACCATGGGGTAGCCGTACAGGTAGGCTTCCTTGGCGATGCGACGCGCTTCGGGCGCCGACACGCCATCGATGCCGACGAATTGCGATCCCGTGGCCGCATCCGGCGAGGTGAAGCTGCAGCCGCTCACGCTGGCGGCCAGCGCCAATGCGGCAAGGCCACGGACATAAGGGGAAGATCCGGCGCCGACGGGGCGTATGCGCAT

Protein sequences of DBSCAN-SWA_1

>NZ_CP053618|1565831:1582879|1573939_1574668_-|WP_006385695.1|tail|DBSCAN-SWA
MPITADIQKLEPGALVELFELDASEIGGAVQRFHGYMQVGAIHWQGKQYDPWSIQAEGFEQVGEGQQPSPTLRVGNIGQDEKGDPLPGVISALCIHLDDLVGARVVVRRTLGKYLDAVNFAEGNPTADPQEELPPEVWIVQQKTVETAQVVEFSLSSALDFNGQKLPDRPIIAGVCSWLRKGGYRGPYCGYTGSRMFDLDGKPVTDPTLDRCSGLMSDCKKRFGEYEVINFGGFPSADLVRG
>NZ_CP053618|1565831:1582879|1578313_1578604_-|WP_006385691.1|DBSCAN-SWA
MVLALRLGRTLGELMDSIDTHELSLWRELDRTSPLGDERADLLAASLAATVAQAAGAKVRATDMLVRWGAHDEEPPAEAGADALKAFLLSKAGKGS
>NZ_CP053618|1565831:1582879|1576628_1576973_-|WP_080684394.1|tail|DBSCAN-SWA
MSMAIEVFNWSPRPNPVGTLKDRTLRVQFGDGYEQEAADGIHAATQSWPLEFVGREAYVRPILEFVKRHAGYRAFFWTPPMGEQGYYKAREVRLRAMEGDMFALSFTMDQVFKP
>NZ_CP053618|1565831:1582879|1565831_1566650_+|WP_006385703.1|DBSCAN-SWA
MTTKNPIPGDIAALPVDLTGQRVIVTAGAAGIGAAIAGAFAARGAQVHICDVDERALAACPHPWSRADVSQRDQIDRYMQEALARLGGLDVLVNNAGIAGPTAGIADIAPQELDATLDINLASQFHTVRHALPALRQAGGGSIINISSVAGRMGVPMRTPYAATKWGVVGLTRSLAVELGGYGIRVNALLPGLVAGPRIDRVIEARARNMGVTVAEETRLELAGVSLGQFVRAADIANMALFLASPFGAMVSGQAISIDGDLQSLPWQPPAD
>NZ_CP053618|1565831:1582879|1568926_1572430_-|WP_173011249.1|DBSCAN-SWA
MESPDSLHSTAYARVIDLLGEGEIYGPVHGMDNALRDVYLNGTPVANEDGSLNFSGASIDFRTGTQWQDPLPGFPASESTIGINAELKSSQPWTRLFTNLQASAVRVTLAVEGLSRADTKNGDINGYRVEYVIELNTDGAGYQVVLSTAFDGKTTQRYTRSHRIDLPRARQGWTLRVRRITPNANSNTISDRTVVDTVTEIIDAKLRYPMSALVGIKIDASQFQSIPTRAYHVRGRIIRVPSNYHPDLRSYDGVWDGTFKLAWTNNPAWIFYDLVSNDRYGLGTRVPAGWLDKWGLYQIGRYCDEMVDDGFGGKEPRFTCNVYLQQAADAYRVVQDFASIFRGMAYWANAAVFASADMPGDPVYTFSSANVVDGRFSYAGSALTTRYTVALVSWSDMSEMGRQKVEYVENREGIARYGIQQVEVTGFGCTSRGQAHRIGKWMLLTSNLETRSVTFSVGLDACRVRPGSVIRVADQHLAGRRIGGRIREGTVSKVTVDAELGVRPGDRLTVNLPNGLSETRVVAAAVGTGLTVDNVAFTVDSTELTADLVGLPGTVLHITVTTPFSQAPEAECVWTLESEALSAQTFRVLSVKRKEGLVAEISAVQHEPGKFDNVDFGTRLDPKPITVVPPSVQPAPGYIRLASRSVIDQGIARHVGIISWDAAPSAVAYQVQWRRDNSDWVEAGRTGALTLELPDIRAGAYVARVRAINVSDISSVWVNSTETTLEGDIAPPPALALLAAKSLVFGIELRWAFPEGRFTAQRTEIWYSASNDRASAIKLGDFAFPQSAHTLMGLSAGKRFYFWGRIVALNGEIGAWYPADQGVMGESSWEASEILEYLNGKISRDELAKDLVGTIDGLTTGLDETRAAITAEETKRADADGALSSRVDTVLATANGAAAGVEQARTALVGLDGKLKATWSVKAQVTQDNKVYAAGMSLGAYTQPDGQVQTSVYFLADRLALLNLANGATTTPFVIENGQTFINDAVIGTGRITNAMIRSLDAGKIDAGYINVDRLEANALTAKLANLGTAYISRAHIRDAQVDTLSIAGNAVTIPTSWAGNTAGTVVINSNVAGPVVVIAYRSGYAGRASTLRIYVNGALVEAAAGSHTVWQSGSGEGTQPLEYTSLPLTAVAVGNAGVGNTTITVNSSSSESNQATIRIVALMVKR
>NZ_CP053618|1565831:1582879|1568332_1568569_-|WP_024070527.1|DBSCAN-SWA
MKIRHYEPYAPLRARAYPAIGDQLDAIMKFAAHLQSSGQALPEPVAQWVAQCQGVKQRYPKPASVDAGGGADLARNPT
>NZ_CP053618|1565831:1582879|1580665_1581361_+|WP_054448642.1|DBSCAN-SWA
MALGKQIRHYRAALGLTLEQLEARTGVGVGTIAALEGRDSERSKYASRLAAGLGLTLEQLLDETAQYPPDVVLADTGGASRADDGAAGDLRIPRFDTGGAMGAGVELRDQPGVIQSLRVSQEWLHKNLRHYTAAANLCVVTGFGDSMRPMYNPGDPLLVDLGVVKADVDGVFFFRVGNEGFIKRLQRIPSARGLLIRAKSENTKYDAWDITEDMDLQIFGRVLKVWRSEDL
>NZ_CP053618|1565831:1582879|1576969_1578256_-|WP_054448641.1|tail|DBSCAN-SWA
MTTIQTAAQIAAETAALKQQTTELNRNCTALKARGSELAKTATAGAKNTAVTRLGTAEKAKATQALDRNARAIRSEAVEQTLADMRKTGALLGVDSEVGRMRVETEIGRFSGESDDDKVSLLAGASRLDKLRAQMKMSAYIQSLANPDAAANEEKRQKQEALDQALSDGTLSQDKYDTARRGLGLVKRDGDFMLDVNDKLLESARNGASKIQDILGTKMYDFVADKFDKLGLSFLNNVAKMVTSAASAKLMETLLGNSFMEGKGGVGGWIGKAGSFLSDLFSGGGGISVGSSFVSGGTALSFFPSAKGNAFTNGMVTSPVAFPMGVMGEAGPEAIMPLHRGADGSLGIRAAFPSVGGDTNPVAGGVAVNVYVQDGNVSASSESGEGGWQQFGQQIGEYVTQLVDRRMSQSYRQGGLAWQANNNRLAGA
>NZ_CP053618|1565831:1582879|1578603_1579077_-|WP_024070536.1|tail|DBSCAN-SWA
MTDTSINSPARAAGVRGLAADPLAGFAHETLTVPQWQDARVIVRAPSAGDHLFHIRAIWAAAGVVPGEDNETVRAKLDAPGVDYTRASASLLVRTLFEQTEHGPRRVFSDDDVDMVAAAYGPAHATLVARAIELGNLGEGAQERAKKPSRKRQTSVS
>NZ_CP053618|1565831:1582879|1567739_1568336_-|WP_006385701.1|tail|DBSCAN-SWA
MTQSLTTIRLYGRLGAEFGRLHRLAVSSTAEAVRALCALLPGFETRLLDSESRGVRYACFIGRRNLAEAELGRPAGNEDIRIAPMPTGAKRGGLMQVVVGVAMIVASFIPGVNVALWAGASTSLMTMGVAMTLGGVVQLLTPQQRALSVKDGPNNGASYNFNGPVNTTAQGNPVPVLYGELFVGSATISAGIYSEDQV
>NZ_CP053618|1565831:1582879|1568549_1568921_-|WP_049055152.1|DBSCAN-SWA
MNMHTASFYDPTGRIIGVMRGPRESVDATAQVTGHPFVDGEGNPESQYVRENALVSRPESPAILARHTLSALPIPCTIKIGDRAYPCNDTTAELAFDQPGTYHVTVEAWPYLNKEFTVENPPL
>NZ_CP053618|1565831:1582879|1579082_1579550_-|WP_006385689.1|DBSCAN-SWA
MAGTTVSQFVQTQGTQLEVSTTATEDLGAAGLAYADLAITIKDPNFQGGQTTEIDVTVLKSTAKEYALGLDDSGTFSMAGNWKAGDPAQKALVAARSDKKTRAFRVTFADGAKFEFLGLVTQYQWQGQLDNVVSATFNVRVTGAVKMTDAPANGG
>NZ_CP053618|1565831:1582879|1566668_1567598_-|WP_053497395.1|DBSCAN-SWA
MKRNFNIHDLRIFYTVVMTGSTRQAAQAMHLTQPAVSHAISRLEQATGVQLFDRSHKTLRPTEAGQYLYSEAKHVLDELVRIDEALHSIEQFGGRNLRIAASPALALAYAPDAVRRYLDANGTRPFSIDLESSVQVISAVETMRADFGLGAVSRDSARLAFLPFLRTEVMAIVHRDHPLARQEAVAVGDIRPDSYVQPLWSDYVMPQGDIAESLQLRSGMQAHMSLLPGTVRAVRGISMVNALSAADIVPAYPELVALPLASRQWFDFVLITRKESASQDLAERLLDALRAAAEDRRHGVYAHTIQLLA
>NZ_CP053618|1565831:1582879|1574670_1576632_-|WP_173010551.1|tail|DBSCAN-SWA
MTAIKQINIGAAPNDQTGDQLRSAFDKVNANIAELDRRTVANATAAAIAELKAADAGKAADVADGKAVAAQRTGDTADAAARQARQAADEADAKALHAQASADSAGAAASQAQRSAQAAADAADRAQGTADAALPRSDKGKPEGVAPLGADGAVPDEYRPKRKCVVVQGNVDLNEYKRPVEVFLSSSAGVSNLPAGLNAPAFLLVEAAGDAAVQTLSSREASPRLYFRTLLSQNAWTPWREAGTVQDITGTGVDFNSMKSSGAFLWRTAYTLENGANYPKLQALRQCGEVSVLDLSGVVMQRLRYGALKADASGPEFSRQFVPAGDGTATGGWTRWRYVGAISDAADLASEDCGDVWFEGAGWRRWSQAQGGYVRFSPPVAHIWQDRSTQDYANGPLIRSLIDENCYFTVAGNNGKGAIFRATPYADPNSPTMIMACGTGVATLGTTKNGWGGPMPVRFITDDIERGRIIGSRWVFGPDLLTPPPYTHIATINYLGANYEYGLIFKPRNAGTTVAVGFMNSANSLVGSIQVTDSITQYNTASDYRLKHDVAATPIAESYSRVMGVRVVDYSMADAGIRYRGAIAHELQALIPHAVTGIKDEMIKMPGMEESVPAYQQVDYSKIVPDLIAALQHADMRINALEERVKALTKMEA
>NZ_CP053618|1565831:1582879|1579799_1580369_-|WP_102949899.1|DBSCAN-SWA
MRAPQDWIAAASQAGAAIARSLSARPAAAAASRQEGARGQHQKGQNMTREESDQVEALIMEWYHWSRGYRPHLGVGRVAAFARGMTSDEAYDDEDVDARLAATRGEQTELCIDELPWQQRSAIGVHAGNKAAGARVFSNPRLTPEQQHAAYQEAKAALLPALRRRALVTAPQVRHADRAKPCGARGASA
>NZ_CP053618|1565831:1582879|1581421_1582879_-|WP_173010552.1|DBSCAN-SWA
MRIRPVGAGSSPYVRGLAALALAASVSGCSFTSPDAATGSQFVGIDGVSAPEARRIAKEAYLYGYPMVARYQAIYSTNIDQGGAQYKGPFNTFSHAAPAVTPDDNATAAPNVDAPASSAVLDLRAEPVVISVPPMESRRYFALQLTDLYGYNFAYIGSRATGNGGGRFLVAGPRWKGAPPKGFAQVIRAETDLVSVSGRTQRFAQSDIANVKRIQAGYRIQPLSAYLKKAAPPAPAAVQWIKPEPPTQMRSSLEFYNQLGFLLQFAPVAHSEKTLRKRLDSLRIRPDAQAVTDAMPPRLRQVMQEGMHDGQNDIDKHRVALAGRTDTLFGDRRTLRNDYLARATGAQVGLGTDSREESLSTVLATDMAGLPLDGTQAYTLRFAPRALPPVNAFWSVTLYRLPGQSVVANPIQRYVIDSTMLPALKRDRDGGLTLRIQHQAPAKGGQANWLPAPAGPFMLALRYYWPKPGLLDGSWQTSQVQRAGS
>NZ_CP053618|1565831:1582879|1573157_1573937_-|WP_006385696.1|DBSCAN-SWA
MLKRTMQAIRDHGVATYPQECCGLVLKAGRREWYVPCRNTAASEEHFVMSAQDYAAAEESGRIVAVVHSHPDAPAVPSEADRVACEASGLPWYIVAVEKDLDGKVKAGEIRGFTPEGFQAPLLGRQFAHGVLDCYSLVRDWYARERGIRLPDFAREDGWWQPGHAGDLYMDHYAEAGFRPLAPHETMAPGDVVVMQVRSDRANHAGVFIGPEPLREAPDLFPLPDAMLHHLYGRDSERVVYGGFWREATRLVLRYGERT
>NZ_CP053618|1565831:1582879|1572555_1573161_-|WP_006385697.1|tail|DBSCAN-SWA
MNDKVRLVRLYGWLGKRFGREHRLAVASPAEAVRALCALLPGFEPALLASERRGVRFACFAGRRNLSQDELRHPVGADVIRIAPMLAGAKNGGLFQTMLGAVLIAAAAIYSGGVAAAFQAGGMVQATATMGLSMMLSGVAQMLSPQQRLLSAKDRPDNGASYNFNGPVNTTAQGNPVPLLYGEMFVGSATISAGIYSEDHV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006385703.1|1565831_1566650_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	1.4e-10	49.3
WP_053497395.1|1566668_1567598_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_006385701.1|1567739_1568336_-|tail	tail assembly protein	C7BGD3	Burkholderia_phage	1.9e-49	53.0
WP_024070527.1|1568332_1568569_-	hypothetical protein	NA	NA	NA	NA
WP_049055152.1|1568549_1568921_-	hypothetical protein	NA	NA	NA	NA
WP_173011249.1|1568926_1572430_-	host specificity protein J	A4JX16	Burkholderia_virus	1.6e-260	45.0
WP_006385697.1|1572555_1573161_-|tail	tail assembly protein	Q6JIL3	Burkholderia_virus	1.0e-50	55.7
WP_006385696.1|1573157_1573937_-	C40 family peptidase	Q3HQU3	Burkholderia_phage	1.5e-65	47.3
WP_006385695.1|1573939_1574668_-|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	2.2e-71	58.3
WP_173010551.1|1574670_1576632_-|tail	tail fiber domain-containing protein	A0A0K0KVF1	Prochlorococcus_phage	1.9e-13	36.2
WP_080684394.1|1576628_1576973_-|tail	phage tail protein	A0A0S2SYI2	Pseudomonas_phage	4.8e-21	38.4
WP_054448641.1|1576969_1578256_-|tail	phage tail tape measure protein	A0A1W6JP49	Morganella_phage	2.2e-13	30.3
WP_006385691.1|1578313_1578604_-	DUF4035 domain-containing protein	S4TND7	Salmonella_phage	9.1e-13	50.0
WP_024070536.1|1578603_1579077_-|tail	Phage tail assembly chaperone	A4JX08	Burkholderia_virus	4.8e-27	45.1
WP_006385689.1|1579082_1579550_-	hypothetical protein	NA	NA	NA	NA
WP_102949899.1|1579799_1580369_-	hypothetical protein	NA	NA	NA	NA
WP_054448642.1|1580665_1581361_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_173010552.1|1581421_1582879_-	DUF1254 domain-containing protein	M1IA53	Paramecium_bursaria_Chlorella_virus	1.5e-63	35.4

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_CP053618|4171644:4183031|DBSCAN-SWA
CATGGCACAGGAACTCGATCTGAACGGCCACCGGTACTCCATCGGGAAACTGAGCGCCAAGCAACAGTTCCACGTGTCGCGCCGCATCGCTCCGATCGTTCCTACGCTGATCCCCGTGTTCGTCCGCCTCGCGGCGGGCGGGCGCGGGATCACCGAGGATCCGGGCGGCATGGCCGATGTGCTGCAACCGCTGGCCGATGGCCTGGCGGCGATGAAGGACGAGGACGCCGACTACGTGCTGGACACCTGCATGCAGGCGGTCCAGCGCCGGCAGGAGCATGGCTGGACCGCCATCTGGTCGGCCGGCCAGCGCGTGCCGATGTTCCAGGACATCGACCTGTCGGTCATGTTGCCGCTGGCGCTGCGCGTCATCGTCGGGAGCCTCGGGCCTTTTATACAAGGGCTGCTTACCAGCCAGACCGGCAGCCCCGAGGCGACACAGGCTGGCTGAAGAGCCTGCCCGGTGGCGAGGATTGGCTGCTGGCGCCGGTCCTCGAGGGACTCTGCAAATACGAGTCCCTCAAGGACGGCACCCTGGACCTGGCCGACATCGCGCTCCTGAACGACGCGTTGTCGGTCCGGGCAGACAACAAGGCGGAAGCGTACCGCCGCCACATGGCGGAAAAAAATGGCTAACACAATTCTGTCCATCGACCTGTCGGGGTTGATGGGCCCATTCAAGATCGACAAGGACGACCTGAAGGACCTCAAGCAGGCAATCGGCGACTCGCGCAAGCAGAGCCTGGCCGACGCGCTCGCGGTGTTCGCGGGGCGGGCCAAGAGTGTCGTCGACTTTGCCGAAAACAAGATTGCCCAGTTCGAGCAAGGCTATTTCGCCGCCAGGCTGGGCGGCACCTCGGGCAGGGACATGCGGGCGCTGGAGACGGTCGCGCAGGACTTCGGCGTTTCCGTCGAAGCGATGCGCAACAGTACCCAGGCCTTGCATCGCAATGTGCGCGATGACCCCAGGGTTGCCGCGCTGCTGGAACAGCTGCATATCTCGCCGAGCGATGGCGCGGGCGGCCAGCGCAACACCGCCGATCTGGTGCTGGAACTGAGCGATGCGCTCAAGCGCATGGACCCCGGCCAGGCCGGGGAGACGGGCAGGAAACTGGGGGTGGATGCCGGCCTCGTGGAGGCCCTGCGCGATCCAGCGTTCGGGCAGCGCCTGTCGGTGCAGCGTCACGCCGAAGAAGGCAGCAGGATCGAGGCGGCCGGCGAGCGCGCCCATCAGCTGATGGCCACCATCCGCGCCTTGAGCGGCTCCGTCGACGCGATGTTCGCGCAGGCGTTGCTGACGATGGGCCCGCAATTGCAGCAGACGCTCGACGGCATTTCGGCCTGGTTCAAGGAGAACGGGCAGACCGCCGGCAAGCGGCTGGGCGAAGTCGGCAATTTCGTGTTGTCGATCATGTCGTTGCTGGGGCCGGTGGTCAGCCTGATCACCTGGCTCGACGGCGTGACGGGGGGGCTGAGTTCGCAGCTCCTGTTGCTGGTCGGCGGATTCCTGATGCTGGGCGGCGGCGGCGTCGTGGGAGCGCTGGCAGGCCTGGTCTCGCGACTGGGTGGCATGCGGTCGCTCATCGGCGGGCTGGGCTCCCAGCTGGCATCGTTGCCAGGACGGATCGGCGGTTTCGTGAGCCGGGCCTGGACGGTGACCAGCAATTTCGTTGCTGGCGTGTTCGGCAGGATGACCTCGATGGGCCGCACCGCCGTGACCCAGATGGGCAATATGGCCGGCGCGGTCTGGTCCTGGATGGGCAATATGGCCGCGCGCGGCGGCGCGCTGGTGGTCGATGGCGTCAAGGCCGCGGGCCAGACCGCGTTGCAGTGGGGCAGATCGCTGTGGGAAGCCGCGGGCTCGTGGATCGGCCGCATCGCCGATGGCGCCAAGGCGGTGGTGCGCAGCGTGGCCAGCAGCCCCGCGGCCGTGGGCGCGGGACTGCTGTTGTACCCCAGGCCCCTGGGCGACGGGACGTTGAAATCGCTGGAGGGGATGCCAGGCTTTCCGGCCGGACAGCCCGGCCCGGGCCTGAACCTGCCCGGTGGCGGCATCCGGCCCGAGCACATGGACGGCGCCCAGGTCGAGCCGTGGCGCGATTACCGCTCCGGCTTCGCCACGGGCGAAACGGCGGCCGGCGTGCTGGCCGCGCCCGCGCCCGCATCGGTTTCCATCAACGCCACCACGAATATCCACGTCAATGGGACGAACGATCCCCATGCGACCGGAGAAGCCGTGGCCAATCAACAGAGCCGGGTCAATGCCGACCTGACGCGCAACCTGCAGGGATCCTATGGCTGACTTGAACATCGCGGGCGCCGACATGGTCGGCCTGCTGTCGAAGAAAATCGGCGACATCGTGGTGGAGGCGACGCTCAGCGAGTCGCATGAGGACACGCTCAAGATCACCAGCCACCCGGTGGAGTCGGGCCCCTATGGCAAATCGGCGATCAGCGACCATGCCTTCAAGCAGCCGCTGACGCTGACCTTGAAGTGCGCGTGGAGCAACGCCTCGTATGAGGCGCTGGCGGGCGCGCAGGCCAAGGACGTGGCTAATGGCAAGGCCGCGGCCGACGACTACGCGACCGCCATCTACTCGCAGCTGCTCAGCCTGCAGGAATCGCGCGAGCCGGTGACCGTGGTCACCAGCCGGCGGCGCTACAGCGACATGTTGATCGAGAAGCTCTCGGTCGAGACCAACAAAGACAGCTTCGGCGCCGTGTTCGCGACGGTGACGCTGCGCGAAGTGGTGGTGGTGCAGACGCGCAGCACCTCGCTGCCCCCGTACGCGGGCCAGAAGGAAAAAGAGAAGACCGCGGACAAGCAGAACCTGGGCGTGAAGACGCCCCGGCCCGTGGCGGCCCCCAACGGCGGCTCGCTGCACTGGAACTAGGAGATACGCATGAACTACTTCGAGATACCCGTGTCGCCGATTCCGCAGGTGTTCGCGATTTCGCTGGGCGGCGACGACTATCGGCTGACATTGCAATACCGCGACGGCTGGATCCTGGACGTGGCCGACGATCTGGGCCGGCCGCTGGTATGCGGCGTTCCGTTGGTGGCCGGCCTGAACCTGTTGGGCCAGTACCGCCACCTCGGTTTCACCGGCGGGCTGCGGGTGACGGGGGCGGAATCGCCGGACGACGCGCCGACGTTCACCGACCTGGGCCGCGGCGCCCGGCTTTATTGGGTGGCGGACTGACATGGCCGGGACGACCACAATGGAACCCATCGCCGTGTACGGCGATCCGGTGGACGACGACAAGGGCGTGCGCCAGTGGGGCAGGAAAGTGTCGTTGATCGTCGGCGACGAGGAAGCGCTGGATCTGTCGGCGCTCAGTTTCAGCTTCGCGATCAAGCGCAATGATGCCAAGACGCCCAACACCGCCACCATCAAGGTGATGAATGCCAGTCGCGAGACGGCCAGCATGGTGCAGCGCGAATTCACCCGGGTCGTGCTGCAGGCCGGCTACGAGGGCAACTACGGCGTGATCTTCCACGGCAACGTGGTGCGGGCCAGGTGGGGCGGATCGGGCGACACCGAGACGGTGCTGGAGATCACGGCGGCCGATGGCGACAAGGCCTACAACTTCGCGGTGGTCAATGCGACCGTGCCCAAGGGCTCCTCCCGCGCCGACAAGGTGCGGTTGCTGTGCTCGGCCATGAACCCGTATGGCGTCAGGCAGGGCTACGTGCCCGATCTGGGCGGCAAGACCGCCATCCGCGGAGCCGTGATGTCCGGCATGGTGCGCGACCACATGCAGGACGTCTGTGACGGCGCGAACACGCTGTGGAGCATCCAGGACGGCAAAGTCGTGATCGTTCCCGAGACCGCCTACGTGCCGGGCTCGGTGCCCGTCATCTCGCACGACACCGGCCTGGTCGGCATGCCCGAACAGGCAGAGAAGGGCATCAAGGTGCGCATGTTGCTCAACCCCAGCATCCGCGTGGGCGGGCTGGTCAACCTGGACAACAGCCGCATCGCCGAGTACGGCTACGAGGGGCGCGCCCAGGGCAAGGACGCGACAGAAATCGATCGCGGCGAACAGCGCCGCATCAGCGGCGACGGCTACTACTACGTCATGGAAGTCGAGCATCGCGGGCATACCCGCGACAACGACTGGTACACGGAGATCCTGTGCCTGGCCACCGATGCGACGCTGTTCCCGGGCGACCTGGGACGGGCAGGGGCGGAGGGCGCCGCGGCCAGGCCGGCCGACGTCGTCAAGTAACGGCCCGCGCGGCTTCATTTCAGCAGGATGATTCATGAACCGACTAGAGAATTTGAACGACCCGCAAGCCGCGATCGGCGCGGCGCTGCGCGGCGCGCTGGCGCAGACCTGGACCGCCATGCCGGCCATCATCGGCGCGTTCGACCCGGTGGCCATGACGTGCACCGCGCAACCGGCCATCCGCGCGCGCGTCACCACGCCCGAGGGAACGCAGCGCAGCATGACGTTGCCGCTGCTGGTGGATTGCCCCGTGTACTTTCCCGCGGGGGCAATTGCACGCTGACTTTCCCGGTGAAGCCCGGGGACGAATGCCTGGTGGTGTTCGCGTCGCGCTGCATCGATGCCTGGTGGCAATCGGGCCAGGTCCAGGACCAGGCGGAAGTGCGGATGCATGACCTGTCCGACGGCTTTGTCTATGTGGGCGTGCGGTCGCAGCCGCGGGTGCTGCCCGCGGTCAGCACTCACACGACCCAGTTGCGCAGCGACGACGGCTCGACGTTCCTGGAGCTGGATCCGGCCGCGGGCAAGGTGAGGATCGTGGCGCCGGGCGGCTTCGACGTGGTCGCGCCGACGTCCGAGTTCTCCGGACAGGTGCTGGTCAACGGCCTGCTGAGCTATCTGGCCGGCCTGGTCGGCAGCGGCGGCCAGGGCAATACCGCCCAGATCACCGGCGTGTTGAACGTGATCGGCCAGATCCTGGCCAATGGAAAACGGGTGGACGACACGCACACCCACATCGCCCAAGGGGCCAACGCGGTGACCACACCGCCCAATTGAGGACTCCCATGCGTTACCGAAAACTGGACGCCGACGGCGACTATTCATTCGGCTCGTCACGGGCCGATTTCCATCGCGACACGGCCGCGACCGTGGCTCAGGCCGTCAAGACGCGGCTGATGCTGGCGCGCGGTGAATGGTTCCTCGACGTCACCGAAGGCATGCCCTGGCGCGGCGAGGTGCTGGGCAAGCAATCCAGGGCCAGCTACGACTGGGCCATCCGCCAGCGCATCCTGGGCACGGCCGGCGTGACCGGCCTGGCCGGGTATTCGAGCCGGCTCGATCCGCAAACCCGCGGCCTGAGCGTCACGGCATCCATCTCAACCCTTTACGGCACGGCCACTGTGCAGGCGGCATTATGACGATTCCATCCACGGCCCCGGTCATCGACGCCGCGGGCATACGCGCGCCGAGTTACGGCGAGGTGCTGCAGTATTTCAAGGAGCAGTACCGCGGCATCTACGGCGCGGACACCTATCTGGAGGCGGACAGCCAGGACGGCCAGTTGGTGGCCCTGTTCGCCCTGGCCATCCACGAGGCCAACACGGCGGCGATCAATGTGTACAACGCGTTCTCGCCCGCCACCGCCGCCAATGCGGCGCTGTCCAGCAACGTCAAGATCAACGGCCTGGCGCGCGGCGTGGCGACGCGCTCTGCGGTGGACCTGCGCATCGTCGGGCAGGGCGGCGTCACCATCGTCGATGGCGTGGCGACCGATGCCAATCGCGGCCGCTGGCAATTGCCGTCCAGCGTCACCATCCCGCCTGGCGGCGAGATCACCGTCACCGCGCTTAGCCAGACGCTGGGCGCGGTGACGGCGCCGGCCGGCAGCATCAACCAGATCGGCACGCCGACGCTGGGCTGGCAGTCCGTCACCAATCCGGCGGCCGCGACCCCTGGCGCGCCGGTCGAGAGCGATGCCGCCCTGCGCGTGAGGCAGGCCATCTCGGTGGCCCTGCCATCGCGCAGCGTGCTGGAGGGCACCATCGGCGCGGTGGCGTCGGTGCCCGGGGTATTGCGCCATGCCGCCTTCGAGAACGACGCCGCGGTGGTCGACGCCCACGGGCTGCCGCCGCACAGCATCGCCCTGGTGGTCGACGGCGGCGACGCGGCCTCGATCGCGCAAGCCATCGCCGCCAAGAAGACGCCCGGCACGGGCACGCACGGCACCACCGCGGTGGTGGTGACGGACATCTACGGCATCGCGCATCGCATCCGCTTTTTCCGGCCCACCCTCGTGCCGCTCTCGGTGCAGGTGCAGATGCGGGCGCTGCCCGGGTACACCACGGCCATCGGGCAAGCGGTGCAGCGCGCGGTTGCCGACTACATCAATGGGGTCGCGATCGGCGGCGGCGCCAGCGCCTCGGTGGAATGGGCCGACGCCATCTCGGCCGCGAACGGCGTGGCGGGCAATGGCACGTTCAAGATCACCGGGCTGGCGCTGCGCGGCCCGGCCGGCGATGGCGCGCCGGATGTGCCGCTGGCCTTCAACGAAGCTGCCGCCGCGACGCCCGACGACGTGAAACTCACGGTGAGCTGACATGGCCAATACGGACGACTACATCGCGCGGCTGTCGGCCTGGCACCGCGGCAAGCCCAGGTTCGTTGCCACCGTGACCGCCCTGTGCGGCGCGGCGGCCAGCCTGCGTGAGTTGTACGGCGGCATGCCGGCGGCTTTCGACCTGGACCTGGCGGTCGGGGCGCAGCTGGATGCCGTGGGGCGCTGGGTGGGGCTGGACCGGAAGGTCCGCACGCCGATCGCCAACGTGTATTTCTCGCACGACACCGACGGCCTGGGTTTCGACCAAGGGGTGTGGCAGGGACCGTTCGATCCGGACAACGGCCTGACCGCGCTGGACGACGACACCTATCGCCTGCTGCTGCGCGCCAAGATCGGCGCCAACCACTGGGACGGCACGCTGGAGGCCTCGGCCGCCATCCTGGAGCGCATCTTCGGCGGCGGCACCCACGTGTTCATCCAGGACAACGGCGACATGTCGGTCGACATCGGCGTCGCCGGCACGCCGCCGTCGGCGCTGTTCCTGGCGCTCCTGACGGGCGGGTACATCCCGCTCAAGCCGCAGGGCGTGCGCATCAGTTACTACGTCATCCCCTCGAACGAGGGGCCCCTGTTCGGTTTTGACGTTCAGAACCATTACATCTCGGGGTTCGACAGCGGACTCTGGGGTTCGCTTTTCGCAGGTTGAATAAGGACAATTCCGTGGCTATCAATCAAATTCTTCCCTTCGGCACCGTGCCCGGCGCCAACGTGCTCGATCCCGCCGACTACCAGGCCCTGGCGGCCCGGCTGGGCGGCTTCTCGGCCGGCACGGCCAAATCCAAGGAACTCAACACCGTCTGGCGCCAGGCGTCCTTCGTGGCCGCCATGATCGGCCAGTACATCGCCGACAAGACGGGCCAGGACGTACTCGACGACGGCGACCTGGCGGCGCTGCAGACCCGCTTCGTGGCCGCGCTGGCGGCGTCGCCGGCGCTGACCGGGACGCCGACCGCGCCGACGCCGGCGGCGGGCGACAAGAGCGCCCGTATCGCGACGACCGCGTTCGTGGCGGGAAATTTCCCCAAGATCTACTCGATCAATGCGCTGCCGACGCAGGATGTCGGCCCCATCATCGTTGCGGAATGCGCCGAAGTGTGGAACTGGGTGGCCGGACAGTATTTCACCGGTTACCGCTCGCCCCTTTGCGGCCGCCCGTTGGATGGCCATACCAACCTGCCGCTGGCCAGCGAGGTCGACGCCGCCGGCGGTTTGCTGTCGAAGACGGATTACGCCGCGCTGTGGGGTTATGCGCAGGAGCAGGGGTTGGTGAAAACCGAGGCCGTGTGGTCGGCAAGCCGCGGCAGTCATTGGTTTTCGGACTATTCGGCGACGCAGTTCCGGGTGCCGGATCTGCGCGATATGTTCCGTCGATTTACCGGGACTGACGCTGACACTGCAAATGCGAGAGCGATGGGTACGCGTCAAAACGATGAACTGAGGACCCATTCGCACAGTGCCAGACAGGCGTCTTCGTCCGCGACGATCGGGACCCAACTCTATTTCGCGCGTGATGCTGGTGAAGTTACAACATCCTCACTAGTGCTACCGTTTGGCGGCAAGGAAACACGACCCTTCAATACTGCATATCGCCCTCGTATCCATGCATGACGCTGTCGGCAGCGTAGGAGGTGGGCGGCCTGAACCCAGCCACGTCGACTTCGCTTTTCATCTTTGGATTTTCGCTTGGTTTCATACATGAATCCGGGCGTGATAGGCGGTGTTCACACTAAGGATTTCGGTTGGCGTACGGACAACGCGGCTGGTGTAGAACGGGGTGGTGTCCCCGTTCGTTATGTTTCCCACAAAGCTAATGGAGATCGAGTTTGTACTCTCGGTCTTCAGGTGTATTGCAGAAGCGCCAGACGCTCTCATAAGAGAGCCGATCGCATCCACTGCCGATTGTCTCTGTGATGGACTGACGATCTTTTGTATCGCGTCGGCCTGCCGACTTCCTCGGACTCTCGCATTGCAGTGAGGGAGACGTCATACGTGCAAGCGCGGGTGATAAGCAACGTTTGAGCCTCGGGTCTCGTGTCCGCCCGTAGGGCTCACGCCCTGACTACCATCTCTCGCTACGTATTCCGATTCAGACCCGTTCGCGTTGAAAGGCCACAAGTTATTCCCTCCATTAACCATTCGCATGGCTGAGCTAACGCCGCCACCCGACCGCTGCAATATGAGCGTGTGGACGTGCGCCTTCATTGCATCCGCCTGACGCGAACCGAGTGCCCGCACATTTGCAGTGCAAATCTCATTTTCAAGGAGTAAAACAACATGCAGAAAGCAGTATTCCAAGCCGATAACGACGGCCTTTACCTGTATCAATCGACCGCGAATGAACTGGCCTTGACGCCGGGCACATTCAACATCCCCTACGGCGCATACGAGGACGCGCCGCCGGCGCCGCCGGCCGGAAAATGGCCCCGGCGCCTGGGCGATGCCTGGGCCATGGTCGATGACTATCGCACCACGCCGCTGTGGGTGGTGGAGACGGGAGCGCCGTATTCGATCGGCGCGCAGCATGACGGCACGATCGGCAAGGTCAGCTATCCGGGCTGGGGGGAATTGCCGGCTTGGCTGACCGCGGTGGAACCGCCGCGCCCGGTTGAAAGCGCTGCCGCGTAGCGTCAGGCGGCCAGGGGCAACGTATCCAGCTCGATCTCGCGCTCGCGCCGCATTTCCTCGAGCTGGCGCCGGCCTAGCTGGCTGCGCGCCAGCTTCTGGGCCAGTTCGCGCCCATGCGGGTGGTAATAGCGCAGCAGCATGCGGGTGTCGACGTTGCCGTTGACCTTGGCCAATTCATGGATCTGGAACACGGTGGCAAGTTGCGACGTGCCTTCGTGTCGCAGATCATGGAATCGCAGGTCGCGGAAGTAGGCGGGATTGGGGCGCCGGCCATAGTGCCGGCACATGCCTTCGTATCGCGATCGGGCACGGCGACGGGCGCGAATGAATGCCCGGGTGACCGAGCCGGGTTGCATTGCGAAGATGCGGCCTCGCATCGGTTTGCCTGTGACCCAGCGGCGCAGGGCCTCGCGGGCCCTGGGGGTAAGCGGAACATCGCGGGCCCGGCCATTTTTCGTGTGGGGTAGATGCACCACTCCGTGCATCAGATCCAGATGCTCGCGCTGGATCCCCACGACCTCGGACCGGCGCATGCCGGTTTCCTTGGCCACCGTCAGGATCGTGGGTAGTTCGGCCGAGCGGGTGGCGCGGATGATCCATTCCAGTTCTTTGCGCGGACAGTCGTCCTCCGACAGCCCGCGCAGGGTAATGCGGTCGAACAGACGCCGGTCTCGAGCGTCGTCCACAGCCGGACGTCGCACCAGCTGGACAGGATTGGCCAGCTGGTCGAAACCCCAATCCTTTCGGATCACCGTATAGACGTGTGACAGGAAAGCCATGCGGCGCACCACGGTGGCCGGGGCACGATCCTTGAGCCATTCGTCGCGCAGTTCCGTCAGGTCCGAGCTGCGGATGCGATCGACCGGGCGGATCGCCAGACGCGTGGCGCGCCAGATCCGCGCGATCGACTGTTCCGACGTATGGCCTTTCTTGGTTGCCGAGACCTCGAGGAGATAGCGGGCGAGCGCCTCGGCGAGGGTCGGAGCGGTCTTGCGGCGAGGTTGGCGGCGGGTCCAAGGTTTCATGGCAGGTCGGACTGAAAGGAAAGGGAAATAGACAGGGAAGATACCAGGACGCATGCAGGCAGCGCCTGCACCAAACGGACGACAGTGTCGCCCGCATTTCAATTTGTCCATCCGGTGCGCCATTGCGGCGCCCGTGATGTTCACGGGAGGCAGCAATGCGCACCGTCGACAGGAGCGGTGTAACCATGGAACCGGCATCTACAGGATTGGGCGGCTGGGCCGCCCTGAAAATCGCGCTGGCCTTCGGCATGCCGGCGGCGATGGCGGCCTTGATCGGCATGTTGCTGATGCCGCCGCGCACGCCGCGCGAATTCGTCGCGCGCACCGCTTGCACGGTGGTCAGTTCTTTTCTGTTCGGGCCGTTGCTGGCGATCGCCATGATTGCCTGGATGCCCGACATCATGTCGTCCGCCTATTGGATGGCGCAGCGCACCGGCTTGGGCGAGGACGGTCTTCTGGCCATGTTCTATGTCCTCGGCCCCTGCATGCTGCTGGCTGGCTTGCCGGCCTGGTGGGTGCTGGGCGCCTACCTGCGCCTGACCGCCAAGCTGCAGAACCAGGACCTGGTGGACTGGGCGGTGGAGATCCGGCGCAAGACGCTGGGCATGGATACCCAAACGGATAAGGAGGGCAGGCATGACGCTTGACCAGATCACGGATCACGCGCTGCGGCCGGCGATGGCATTACTGCCGGCGCGCATGGATACGAGCGAGGCGCGTTGCATGCTGCTGGCGATCGGCCTGCAGGAAAGCCGCTTCGTGCATCGGCGCCAAATTGGCGGACCGGCGCGCGGTTTCTGGCAGTTCGAGAGGGGCACGTCCGCCAGCCGCGGCGGTGTGTGGGGCGTGTTCCTGCACGCGGCGAGCAGGGATTGGCTGGCCGAACTGTGCCGGGCGCGCGGCGTGGCCATCGATCCGGACGCGATCCACGCCGCGCTCGAGCATGACGACGTGCTGGCGGCCGGCGTCGCCCGGTTGCTGCTCTGGACCGATCCGAAGGCGCTGCCGCCGGTCGGTGAGACGAATGCGGCGTGGGCGCTGTATCTGCGCACCTGGCGGCCGGGCAAGCCCAAGCCTGACAGTTGGCCCGCCCTGTATCAGCAGGCCGTTGCCGCCGTCCGGGCGCGGGCAGACAGGAGCGCGACGCATGTTGCAGCAATGGATTAA

Protein sequences of DBSCAN-SWA_2

>NZ_CP053618|4171644:4183031|4172271_4173945_+|WP_173010862.1|tail|DBSCAN-SWA
MANTILSIDLSGLMGPFKIDKDDLKDLKQAIGDSRKQSLADALAVFAGRAKSVVDFAENKIAQFEQGYFAARLGGTSGRDMRALETVAQDFGVSVEAMRNSTQALHRNVRDDPRVAALLEQLHISPSDGAGGQRNTADLVLELSDALKRMDPGQAGETGRKLGVDAGLVEALRDPAFGQRLSVQRHAEEGSRIEAAGERAHQLMATIRALSGSVDAMFAQALLTMGPQLQQTLDGISAWFKENGQTAGKRLGEVGNFVLSIMSLLGPVVSLITWLDGVTGGLSSQLLLLVGGFLMLGGGGVVGALAGLVSRLGGMRSLIGGLGSQLASLPGRIGGFVSRAWTVTSNFVAGVFGRMTSMGRTAVTQMGNMAGAVWSWMGNMAARGGALVVDGVKAAGQTALQWGRSLWEAAGSWIGRIADGAKAVVRSVASSPAAVGAGLLLYPRPLGDGTLKSLEGMPGFPAGQPGPGLNLPGGGIRPEHMDGAQVEPWRDYRSGFATGETAAGVLAAPAPASVSINATTNIHVNGTNDPHATGEAVANQQSRVNADLTRNLQGSYG
>NZ_CP053618|4171644:4183031|4176661_4177015_+|WP_020924456.1|DBSCAN-SWA
MRYRKLDADGDYSFGSSRADFHRDTAATVAQAVKTRLMLARGEWFLDVTEGMPWRGEVLGKQSRASYDWAIRQRILGTAGVTGLAGYSSRLDPQTRGLSVTASISTLYGTATVQAAL
>NZ_CP053618|4171644:4183031|4180841_4181864_-|WP_173010865.1|integrase|DBSCAN-SWA
MKPWTRRQPRRKTAPTLAEALARYLLEVSATKKGHTSEQSIARIWRATRLAIRPVDRIRSSDLTELRDEWLKDRAPATVVRRMAFLSHVYTVIRKDWGFDQLANPVQLVRRPAVDDARDRRLFDRITLRGLSEDDCPRKELEWIIRATRSAELPTILTVAKETGMRRSEVVGIQREHLDLMHGVVHLPHTKNGRARDVPLTPRAREALRRWVTGKPMRGRIFAMQPGSVTRAFIRARRRARSRYEGMCRHYGRRPNPAYFRDLRFHDLRHEGTSQLATVFQIHELAKVNGNVDTRMLLRYYHPHGRELAQKLARSQLGRRQLEEMRREREIELDTLPLAA
>NZ_CP053618|4171644:4183031|4180488_4180839_+|WP_070780627.1|tail|DBSCAN-SWA
MQKAVFQADNDGLYLYQSTANELALTPGTFNIPYGAYEDAPPAPPAGKWPRRLGDAWAMVDDYRTTPLWVVETGAPYSIGAQHDGTIGKVSYPGWGELPAWLTAVEPPRPVESAAA
>NZ_CP053618|4171644:4183031|4182500_4183031_+|WP_020924452.1|DBSCAN-SWA
MTLDQITDHALRPAMALLPARMDTSEARCMLLAIGLQESRFVHRRQIGGPARGFWQFERGTSASRGGVWGVFLHAASRDWLAELCRARGVAIDPDAIHAALEHDDVLAAGVARLLLWTDPKALPPVGETNAAWALYLRTWRPGKPKPDSWPALYQQAVAAVRARADRSATHVAAMD
>NZ_CP053618|4171644:4183031|4174546_4174846_+|WP_006388474.1|DBSCAN-SWA
MNYFEIPVSPIPQVFAISLGGDDYRLTLQYRDGWILDVADDLGRPLVCGVPLVAGLNLLGQYRHLGFTGGLRVTGAESPDDAPTFTDLGRGARLYWVAD
>NZ_CP053618|4171644:4183031|4171644_4172094_+|WP_024068262.1|DBSCAN-SWA
MAQELDLNGHRYSIGKLSAKQQFHVSRRIAPIVPTLIPVFVRLAAGGRGITEDPGGMADVLQPLADGLAAMKDEDADYVLDTCMQAVQRRQEHGWTAIWSAGQRVPMFQDIDLSVMLPLALRVIVGSLGPFIQGLLTSQTGSPEATQAG
>NZ_CP053618|4171644:4183031|4177011_4178193_+|WP_173010863.1|DBSCAN-SWA
MTIPSTAPVIDAAGIRAPSYGEVLQYFKEQYRGIYGADTYLEADSQDGQLVALFALAIHEANTAAINVYNAFSPATAANAALSSNVKINGLARGVATRSAVDLRIVGQGGVTIVDGVATDANRGRWQLPSSVTIPPGGEITVTALSQTLGAVTAPAGSINQIGTPTLGWQSVTNPAAATPGAPVESDAALRVRQAISVALPSRSVLEGTIGAVASVPGVLRHAAFENDAAVVDAHGLPPHSIALVVDGGDAASIAQAIAAKKTPGTGTHGTTAVVVTDIYGIAHRIRFFRPTLVPLSVQVQMRALPGYTTAIGQAVQRAVADYINGVAIGGGASASVEWADAISAANGVAGNGTFKITGLALRGPAGDGAPDVPLAFNEAAAATPDDVKLTVS
>NZ_CP053618|4171644:4183031|4182019_4182511_+|WP_164497481.1|DBSCAN-SWA
MRTVDRSGVTMEPASTGLGGWAALKIALAFGMPAAMAALIGMLLMPPRTPREFVARTACTVVSSFLFGPLLAIAMIAWMPDIMSSAYWMAQRTGLGEDGLLAMFYVLGPCMLLAGLPAWWVLGAYLRLTAKLQNQDLVDWAVEIRRKTLGMDTQTDKEGRHDA
>NZ_CP053618|4171644:4183031|4173937_4174537_+|WP_026384173.1|DBSCAN-SWA
MADLNIAGADMVGLLSKKIGDIVVEATLSESHEDTLKITSHPVESGPYGKSAISDHAFKQPLTLTLKCAWSNASYEALAGAQAKDVANGKAAADDYATAIYSQLLSLQESREPVTVVTSRRRYSDMLIEKLSVETNKDSFGAVFATVTLREVVVVQTRSTSLPPYAGQKEKEKTADKQNLGVKTPRPVAAPNGGSLHWN
>NZ_CP053618|4171644:4183031|4174865_4175876_+|WP_054437471.1|DBSCAN-SWA
MEPIAVYGDPVDDDKGVRQWGRKVSLIVGDEEALDLSALSFSFAIKRNDAKTPNTATIKVMNASRETASMVQREFTRVVLQAGYEGNYGVIFHGNVVRARWGGSGDTETVLEITAADGDKAYNFAVVNATVPKGSSRADKVRLLCSAMNPYGVRQGYVPDLGGKTAIRGAVMSGMVRDHMQDVCDGANTLWSIQDGKVVIVPETAYVPGSVPVISHDTGLVGMPEQAEKGIKVRMLLNPSIRVGGLVNLDNSRIAEYGYEGRAQGKDATEIDRGEQRRISGDGYYYVMEVEHRGHTRDNDWYTEILCLATDATLFPGDLGRAGAEGAAARPADVVK
>NZ_CP053618|4171644:4183031|4178194_4178860_+|WP_020924454.1|DBSCAN-SWA
MANTDDYIARLSAWHRGKPRFVATVTALCGAAASLRELYGGMPAAFDLDLAVGAQLDAVGRWVGLDRKVRTPIANVYFSHDTDGLGFDQGVWQGPFDPDNGLTALDDDTYRLLLRAKIGANHWDGTLEASAAILERIFGGGTHVFIQDNGDMSVDIGVAGTPPSALFLALLTGGYIPLKPQGVRISYYVIPSNEGPLFGFDVQNHYISGFDSGLWGSLFAG
>NZ_CP053618|4171644:4183031|4178874_4179822_+|WP_173010864.1|DBSCAN-SWA
MAINQILPFGTVPGANVLDPADYQALAARLGGFSAGTAKSKELNTVWRQASFVAAMIGQYIADKTGQDVLDDGDLAALQTRFVAALAASPALTGTPTAPTPAAGDKSARIATTAFVAGNFPKIYSINALPTQDVGPIIVAECAEVWNWVAGQYFTGYRSPLCGRPLDGHTNLPLASEVDAAGGLLSKTDYAALWGYAQEQGLVKTEAVWSASRGSHWFSDYSATQFRVPDLRDMFRRFTGTDADTANARAMGTRQNDELRTHSHSARQASSSATIGTQLYFARDAGEVTTSSLVLPFGGKETRPFNTAYRPRIHA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4166652:4166667	attL	NA	NA	NA	NA
WP_024068262.1|4171644_4172094_+	hypothetical protein	A0A0N7IRF3	Acinetobacter_phage	1.1e-17	36.5
WP_173010862.1|4172271_4173945_+|tail	phage tail protein	NA	NA	NA	NA
WP_026384173.1|4173937_4174537_+	hypothetical protein	NA	NA	NA	NA
WP_006388474.1|4174546_4174846_+	hypothetical protein	NA	NA	NA	NA
WP_054437471.1|4174865_4175876_+	hypothetical protein	A9YX04	Burkholderia_phage	4.8e-77	50.3
WP_020924456.1|4176661_4177015_+	hypothetical protein	A9YX11	Burkholderia_phage	6.1e-35	66.7
WP_173010863.1|4177011_4178193_+	hypothetical protein	A9YX12	Burkholderia_phage	7.5e-130	62.6
WP_020924454.1|4178194_4178860_+	DUF2612 domain-containing protein	A9YX13	Burkholderia_phage	2.8e-73	60.2
WP_173010864.1|4178874_4179822_+	hypothetical protein	A0A0M3ULD8	Salmonella_phage	1.7e-15	52.9
WP_070780627.1|4180488_4180839_+|tail	phage tail protein	NA	NA	NA	NA
WP_173010865.1|4180841_4181864_-|integrase	tyrosine-type recombinase/integrase	A0A2H4JE37	uncultured_Caudovirales_phage	8.2e-24	32.3
WP_164497481.1|4182019_4182511_+	hypothetical protein	A0A0U5LBV3	unidentified_phage	6.3e-14	37.2
WP_020924452.1|4182500_4183031_+	hypothetical protein	A0A2H4JFP9	uncultured_Caudovirales_phage	1.8e-43	58.0
4182530:4182545	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_CP053618|5035629:5043565|DBSCAN-SWA
TATGACCACCACCTTGACCGCCGTCTGCTCGCACGAGGAAGACGTCAAGAAAAGCCGCTTCATCGCCCATGCCGCGCCCGTCGCCACCGTCGACGAGGCCATGGCGTTCTTCGCGGCGCACAGCGAGCCCGAAGCCACCCACAACTGCTGGGCCTACCGCATCGGCCAGGAATACCGCTTCAATGACGACGGCGAGCCCGGCGGCACGGCAGGGCGTCCGATCCTGCAGGCGATCGAGGGGCAGGGCATGGACCGCGTGGCGGTGCTGGTGGTGCGTTGGTTCGGGGGCGTCAAGCTGGGCGCGGGCGGACTCGTGCGGGCCTATGGCGGCTGCGCCGCCAACTGCCTGCGCAACGGCCCGCGCACCGAGATCGTGGACCTGGCCACGGTGGCGTGCGCCTGCGGCTTCGCCGAGCTGCCGCTGCTGAAGTCGCGGCTGGCGCAGGCCGGCGCGGTGATCGTGCAGGAGGACTTCAGCGCGGACGGCGTGGCGTTGCGCTTCACGGTGCCGCGCGGCGCCGTGGCCGACCTGGAGATGACGGCGGCCAACATCACGCGCGGCCGCTCGGCGTGGGAACAATTGGCGTGACATGCGACAAGGGCCCCGAGGGGCCCTTGTGCGTCACGCGTCCTGGCTGTCCTGGGCCGCGGCGATTTCCTGGTGGACCTTTTCCATGTCGACTTCCTTGATCTTGGCGAGCAGCTCATTGAGCTGGCCGCCGGACAAGGCGCCGGGCTGCGAGAACAGCAGGACTTTCTCGCGGAACACCATCAGCGTGGGAATCGAGCGGATGCCCAGCGCGCCGGCCAGTTCCTGTTCCACGTCGGTGTTGACCTTGGCGAAGGTGACGTCGGGATGCTCGGTGGCGGCCTGCTCGAAAACCGGCGCGAAGCCACGGCACGGGCCGCACCAGGGGGCCCAGAAGTCCACGATCAAGGTGCCGTCCGGCGTGATGGCTTCCTGGAAGCTGTCTTTGGTGAGTTCAACAATACTCATTTTGGATCCTTGCCGCTGGCGCGGCGCAAAGTGTCGGTATCAGCGGCCCGGGGACGCCTGCCCCGGACCGGATGCGGCGACGCGGTTGCCGGTCCTGCCGGTCCATAGTAGAGCGGGGACCGGTCGCGTCGCAATGGTTGGCGCTGTGGCGAGCGCGGTCTGCGGAGCTTGTGGGGCCGGCGGCGGGGCCGCCGGCCTCACGCCGCGGTTGTTGTGGGTACGCCGTCGCGCTGCTTGAGCGCGGCGACGATCTCGAAGGAACGCAGGCGATCGGCGATATCGTAGAAATCGGACACGATCATGACTTCGTCGGCTTCCGTCTCGGCGACCAGGGCTTCCAGCCGGCGTTTGACGGTTTCGGGGCCGCCGACGATGGCGGCGCCCAGTCTTTGATTGACCGCCTCGCGCTCCCATTCGTTCCAGAGCCCGTCCATGCTGTCGACCGGCGGCTGCAACTGCAGGCGGTTGCCGCGCACCAACGACAGGAACTTGAGCTGCTGCGTGGTGGACAGGCGCCGGGCCTCTTCATCGGTGGGGGCGGCCACCACCGGCACCCCGATCATGGCGTAGGGTCGGGCCAGCGTCTCGGACGGCTTGAACAGGTGGCGGTACAGGCGCATCGCCGCCATGCCCTCGGGCGAGAAGTGGCCGGCGAACGAGAACGGCAGGCCCAGTTCGGCCGCCAGCCGGGCGCTGAAATCGCTCGAACCCAGCAGCCAGATGGGGATGTCCAGGCCTTCGCCAGGGATGGCGCGCACCGGCTGGCCCGGCCGCGAAGGCGCGAGAAAGCCGCGCAACTCCTCGACCAGCGCCGGGAATTCCAGGCCGCTGCGCGGGCCGCGACGCAGCGCGTGCTGCGTGGCGCCATCGCTGCCGGGCGCCCGGCCCAGGCCCAGGTCGATGCGGCCAGGGTAGAGGGTTTCGAGCGTGCCGAACTGCTCGGCGATGATCAGCGGCGCATGGTTGGGCAGCATCACGCCGCCCGAGCCGACGCGCAGCGTCGAGGTGTGCCCGGCGATGTGGCCGATCAGCACTGCCGTGGCGCTGCTGGCCACGCCGTTGATGTTGTGGTGTTCGGCCAGCCAGAAACGCTTGTAGCCGAGCCGTTCGACGTGCTGGGCCACCGCCACGCTGTTGCGGAAGGCGTCGGCGGCGTCGCGACCCTGCACGATCGGGGCCAGGTCCAGCACCGAGAAGGGGATGCGGGCCAGGGTGCTCATGCGCGGCGCTCGCGTGGGCGGCGGGGACAGGACGAATGCGGGGTGTGGCGAGACAAGGTCGGCTCCATGGTCTTATATACATGGGGAGTGTATCGGCGAATTCAACCGCTCCCGCCAGCAACCATACGGGCCGGCGGGTTGATAGCCGGACTCAATGATGACGATTTGCCGGGCGGCCCGCGACCCGGGCAGTCGTACCGGTATAGTGGTCACTTCGGCGCCGCAAGCATCGTTCCCGCGGCTCCAGGTCCGCCCCCCGATCGCGCCGCCGCGCCTGCGATTGCCAACATGATCGGCAGCGTCTGGCCGTTTCGTCCAAGACGCGGCCACTCGAATCGGCGATGATGCGGTTTTCTTCTATATCCGCGGGAGACACGCATGAGCGTCACCGGCAATAACCACCAGATCGACAACATCGAATTCAACGTCGCCGACATCGCGCGCAGCAAGCGCTTCTATGGCGACGCCTTCGGCTGGTCGTTCACCGACTACGGGCCGACCTACACCGAATTCACCGATGGCCGCCTCAAGGGCGGCTTCACCACCGGCGAGCCGGTGCGCCCGGGCGGGCCGCTGGTGATCCTGTACGCCGACGACCTGGTCGACGCGCAGCGCCGCGTGACGGCGGCGGGCGGCCGCATCAGCCGGGAGGCCTTCGATTTCCCCGGCGGCCGCCGCTTCCACTTCGCCGACCTCGATGGCTATGAACTCGCGGTCTGGACCGCCGTGGCCTAGCGGCGGGTGCGCGCCGGCATGAAAAAACCGCCGCCTTCCGGACCGGAAGCGCGGCGGTTTTGCATGGGGCGCGTCTGGCGGACGTTATTCCGGGAAGAACGCGTAGCGGATGACGAACAGGATCGCCACCAGCCAGGTGGCCGGATGCACGTCGCGCACGCGGCCGGTAGCGGTCTTGAGCACCACGTAGCTGATGAAGCCGAAGGCGATGCCGTTGGCGATGGAGTAGGTGAACGGCATCACCAGTGCCGTCAGCGCGGCCGGGGTGGCTTCGCAGACGTCGTTCCAGTCGATGTCGATCAGCTCGCGCATCATCAGGCCGGCCACGTAGAGCAGGGCGGGGGCGGTGGCGTAGGCGGGCACGGCGCCGGCCAGCGGCGAGATGAACAGCGCGGCCAGGAACAGCAGGGCCACCACCAGCGCGGTCAGGCCGGTGCGGCCGCCGGCCTGCACGCCCGAGGCGCTTTCAACGTAGGCGGTGGTGCTGCTGGTGCCCAGCATCGAGCCGGCCACGATGGCGGTGCTGTCGGCGAACAGGGCGCGGCCCAGGCGGTTGGGGCGACCCTCCGGCATCAGGCCGGCGCGTTTGGCCACGCCCACCAGCGTGCCGGTGGCGTCGAACACCTCGACCAGCACGAACACCAGGATGACGTGCACGAATCCGGTGTGCAGCGCGCCCAGGATGTCCATCTTGAACAGCGTCGGCGCCAGGCTCGGCGGCGCCGCGAACACGCCCTTGAATTCGTTGTAGCCCAGCGCCATCGACAGCACCGTGACCACCAGGATGCCGATCAGGATGGCGCCGCGCACGCGCAGCGCGTCCAGCGAGGCGATGATGAAAAAGCCCAGGATGGCAAACAGCGGTCCCGGGGTGGTCAGGTCGCCCAGCGTCACCTTGGTGGCCGGATGCGCCACCACGATGCCGGCGCTGGACAGCGCGATAATGGCCAGGAACAGGCCGATACCGGCGGCGATGGCGCTGCGCAGCGAATGCGGGATGCCCTTGACCAGCCAGACCCGGATGCCCGAGATGGTCAGGACCAGAAAGATCACGCCCGAGATGAACACGGCGCCCAGCGCCTGCTCCCAGGTGTAGCCCATGGTCTTGACCACGGTGAAGGCGAAGAAGGCGTTCAGCCCCATGCCCGGCGCCATGCCGATCGGCCAGTTGGCGATCAGCGCCATCACCAGCGAGCCCAGCGCGGCGGCCAGGCAGGTGGCGACGAATACGGCGTTGCGGTCCATGCCGGTGGACGACAGGATGTCCGGGTTCACGAAGATGATGTACGACATGGTCAGGAATGTCGTCAGGCCGGCCACGATCTCGGTTCTCGCGGTCGTGCCGTGTTCACGCAGGTTGAATAGCTTCTCCAGCATTCTTATCCCCAGGGTGCTTGCAGGCTCGGTTTGTCGGAAGGGGGCCTTGGCCGCCCTCGGTCATTTTGTAAACGGGCGTATTTTCGCATCAGTTGTAAACTCTGCCGCCATGATTATTCTCGGCTTTGAAAGCTCCTGCGACGAAACGGGCGTCGCAGCCGTCTGTACGGAACGCGGCCTGCTCGCGCACGCGCTGCACACCCAGATCGCCATGCACCAGGAATACGGGGGCGTGGTGCCTGAACTCGCCTCGCGCGACCATATCCGCCGCGTGGTGCCGCTGACGCACCAGGTGCTGCAGGAGGCGGGCCTGGAAATGTCGGACATCGGGGCGGTGGCGTATACGGCCGGGCCCGGTCTGGCCGGCGCGCTGCTGGTGGGCGCCAGCGTGGCGCAGTCGTTCGCCTGGTCGCGTCACCTGCCGGCCATTGCCATCCATCACCTGGAAGGCCACCTGTTGTCGCCGATGCTGGCCGACCCGCGGCCCGATTTCCCGTTCGTGGCGTTGCTGGTGTCCGGCGGCCATACGCAGTTGATGCGGGTCGACGGGGTGGGGCGCTACGAATTGCTGGGCGAAACCCTGGACGATGCCGCCGGCGAAGCCTTCGATAAGTCGGCCAAGCTGATGGGCCTGGGCTATCCGGGCGGACCGGCGCTGGCGCGCCTGGCGGACCAGGGCGATGCCGCGCGCTTCGACCTGCCGCGCCCCATGCTGCACAGCGGCGACCTGGATTTCAGCTTCAGCGGCCTGAAGACGGCCGTGCTGACCCGGGTCAAGGCGGCCGAGCAGGACGGCGGACTGGACGAGCAGACCCGCGCCGACCTGGCGGCGGCCACCCAGGCCGCCATTGTCGAGGTGCTGGCCGCCAAGTCGATCCGCGCCCTCAAGCAGACCGGCCTGCGCCGCCTGGTGGTGGCCGGCGGGGTGGGCGCCAACCAGCTGCTGCGCGCCAGGCTGGCCGCCGCGCTCAAGCCGCTCAAGGCACAGGCCTATTTCCCGCCGCTGTCGCTGTGCACCGACAACGGCGCCATGATCGCCTTCGCGGCGGCCGAACGGGTCAAGGCCGGGCTGGTGACCCTGGATCCCGATGCGCACGGATTTACCGTGCGGCCGCGCTGGGACCTGGCGGAGATTGGCTGAGCCGGGCAATGAAAAGGGGGCCGCGGCCCCCTTTTCATTTGTGCCGCGACGCCCGTACCGGCGCGCGGATCACTTTTTCTTGCCGCCGCCGATGCGGCTTTCGGTGCCTTGCACCAGGCGCGTGATGTTGGCGCGGTGGCGGTAGAACAGCAGCACGCCGATGATGGCCAGGGCGATGCCCATGGCCGGCTGGGCATACCAGGCCAGGCCGGAGCCGAACACGTAGTAGACCGGCGCGAAGAATGCGGCCACCAGCGAGGCCAGCGATGAATAGCGGAAGAACACCGCGATGATCAGCCAGGTGGCCGCCGTGGCGACCGCCAGCCAGGGCTGGATGGCGACCAGCACGCCCAGGGCGGTGGCCACGCCCTTGCCGCCCTTGAAGCCCAGGAAAATCGGGTACAGATGGCCCAGGAAGGCGGCCACGGCGACCGCGGCCAGTGGCCCGGGGGTGATGCCGGGCGCCAGGCGCTGCGCCAGCCAGACGGCGAACCAGCCCTTGGCGGCGTCGCCCAGCAGGGTCAGCGCGGCGGCGGTCTTGTTGCCGGTGCGCAGCACGTTGGTGGCGCCGGGGTTCTTCGAGCCGTAGCTGCGGGGGTCCTGCAGTCCCATCAGTTTGCTGACGACCACCGCGAACGGCACGGAGCCAATCAGGTAGGCCAGCAGGATGAGCGCCGCGGAGAACGCCAGGGAGGGTTCGGTGATCGCCATGGGTAAGGGGTCCGTTGTTGTCGTGCGTTGTCTCGATGGCTGCGGATTCTACCCCGGCGGCCCGGCGGGCCGGGTACGGGTAAGCGAGAGGCTGATCGGAACCGGGTTCGCCGACGGACATGCCGAGGTCCTCCTTGGACGGTACAATCCAGCGCGTCACCCGCGTTTTATTTTCTTTCGGATGCACAATGCGAATTCTGGTTTCGAACGATGATGGTTATTCCGCCCCTGGGCTCGAAGCGCTGGTCAAGGCGCTGCAGGGCCTGGGCGACCTGACCGTCGTCGCGCCCGAGACCAACCACAGCGGCGCATCCAATTCCCTTACGTTGAACCGGCCGCTGTCGGTGCGCACGGCGTCCAACGGCTTCATTGCCGTCAATGGCACGCCGTCCGACTGCGTCCATGTGGCCCTGACCGGCCTGATGGACGCGCGCCCCGACCTGGTGGTGTCCGGCATCAACAACGGCGCCAACATGGGCGACGACACGCTCTATTCGGGCACCGTGGCGGCCGCCAGCGAGGGTTACCTGTTCGGCATCCCGGCCATCGCCTTCTCGCTGGCCGAGAAAGGCTGGGAGCACATCGATTCCGCCGCCCGCGCCGCGCGCATGGTGGTCGAACGCCATCTGGCGCAGCCCCTGGCCGCGCCGGTGCTGCTGAACGTCAACATCCCCAGCCGCCGGTTCGAGGACATGCACGGCTTTCAGGTCACGCGCCTGGGCAAGCGCCACCCGTCGCAGCCGGTGGTGCGCACCACCACCCCTTATGGCGATCCGGTCTATTGGATTGGGCCGGTGGGGCAGGCGGCCGACGCCACGCCTGGCACCGATTTCCACGCGGTCGCGCAAGGTATGGTGTCTGTCACGCCGCTGCGGCTGGACCTGACCCAGCACAGCCAGCTCGACGAAATCCGGACCTGGGCGGAGCCGCTATGCGTCGACGCGTAAGCCAGCCGGACGTCTCCCAGGCGGTTCCCGGGCGGCCCAGCCCGGTGCGCTACGACTCGGGCCGGCTCAGCCCCGGCGTCACGCCGGCCAACAGCAACACCCGGGTTTCGGCCGCGACCCTGCAAAGCCAGGCCAAGGCGCCGACGCCCGCGGCGGGCGGCAACCTGGGGCTCAATTCGGATCGCCTGCGCCAGGCCATGGTGCAGCGCCTGCGCGCCCAGGGCGTGACCGACGAGCGCGTGCTCAACGCCATGGCCGCGGTGCCGCGCCACCTGTTCGTCGACGAGGCCCTGGCCAGCCGCGCCTATGAAGACGCGGCCCTGCCGATCGGCCATTCGCAAACCATTTCGCAACCCTGGGTGGTGGCGCGCATGATCGCCGCCATCTGCGAAGACCGCACGCCCACCCGCGTGCTCGAAGTCGGCGCCGGCTGCGGCTACCAGGCGGCGGTGCTGGCCCAGTTCGTGCGCGAGGTCCATTCCATCGAACGCATCCGCGGCCTGTACGAACTGGCGCGCGAACACCTGCGCGCCTTGCGGCTCACCACCCGCATCCGCTTGATCTATGGCGACGGCATGCTGGGCCTGCCCGGCGTGGCGCCGTTCGATGCTATCGTTGTGGCTGCCGCCGGCCTGACCATCCCGCAGGCGCTGCTGTCGCAGCTTGCGCCGGGCGGACGCCTGATCGCTCCCGAAGGGGGCTCCAATCAACGCCTGGTGCTGATCGAACGCACCGGCGCGGCCAGCTGGAAACGTACTGAATTAGAGGCCGTGCGCTTCGTGCCGCTGCGTGCCGGAATACAATCTTGA

Protein sequences of DBSCAN-SWA_3

>NZ_CP053618|5035629:5043565|5042800_5043565_+|WP_020927472.1|DBSCAN-SWA
MRYDSGRLSPGVTPANSNTRVSAATLQSQAKAPTPAAGGNLGLNSDRLRQAMVQRLRAQGVTDERVLNAMAAVPRHLFVDEALASRAYEDAALPIGHSQTISQPWVVARMIAAICEDRTPTRVLEVGAGCGYQAAVLAQFVREVHSIERIRGLYELAREHLRALRLTTRIRLIYGDGMLGLPGVAPFDAIVVAAAGLTIPQALLSQLAPGGRLIAPEGGSNQRLVLIERTGAASWKRTELEAVRFVPLRAGIQS
>NZ_CP053618|5035629:5043565|5038223_5038580_+|WP_054438380.1|DBSCAN-SWA
MSVTGNNHQIDNIEFNVADIARSKRFYGDAFGWSFTDYGPTYTEFTDGRLKGGFTTGEPVRPGGPLVILYADDLVDAQRRVTAAGGRISREAFDFPGGRRFHFADLDGYELAVWTAVA
>NZ_CP053618|5035629:5043565|5038664_5039957_-|WP_006388153.1|DBSCAN-SWA
MLEKLFNLREHGTTARTEIVAGLTTFLTMSYIIFVNPDILSSTGMDRNAVFVATCLAAALGSLVMALIANWPIGMAPGMGLNAFFAFTVVKTMGYTWEQALGAVFISGVIFLVLTISGIRVWLVKGIPHSLRSAIAAGIGLFLAIIALSSAGIVVAHPATKVTLGDLTTPGPLFAILGFFIIASLDALRVRGAILIGILVVTVLSMALGYNEFKGVFAAPPSLAPTLFKMDILGALHTGFVHVILVFVLVEVFDATGTLVGVAKRAGLMPEGRPNRLGRALFADSTAIVAGSMLGTSSTTAYVESASGVQAGGRTGLTALVVALLFLAALFISPLAGAVPAYATAPALLYVAGLMMRELIDIDWNDVCEATPAALTALVMPFTYSIANGIAFGFISYVVLKTATGRVRDVHPATWLVAILFVIRYAFFPE
>NZ_CP053618|5035629:5043565|5036822_5037845_-|WP_006388151.1|DBSCAN-SWA
MSTLARIPFSVLDLAPIVQGRDAADAFRNSVAVAQHVERLGYKRFWLAEHHNINGVASSATAVLIGHIAGHTSTLRVGSGGVMLPNHAPLIIAEQFGTLETLYPGRIDLGLGRAPGSDGATQHALRRGPRSGLEFPALVEELRGFLAPSRPGQPVRAIPGEGLDIPIWLLGSSDFSARLAAELGLPFSFAGHFSPEGMAAMRLYRHLFKPSETLARPYAMIGVPVVAAPTDEEARRLSTTQQLKFLSLVRGNRLQLQPPVDSMDGLWNEWEREAVNQRLGAAIVGGPETVKRRLEALVAETEADEVMIVSDFYDIADRLRSFEIVAALKQRDGVPTTTAA
>NZ_CP053618|5035629:5043565|5041167_5041809_-|WP_006388155.1|DBSCAN-SWA
MAITEPSLAFSAALILLAYLIGSVPFAVVVSKLMGLQDPRSYGSKNPGATNVLRTGNKTAAALTLLGDAAKGWFAVWLAQRLAPGITPGPLAAVAVAAFLGHLYPIFLGFKGGKGVATALGVLVAIQPWLAVATAATWLIIAVFFRYSSLASLVAAFFAPVYYVFGSGLAWYAQPAMGIALAIIGVLLFYRHRANITRLVQGTESRIGGGKKK
>NZ_CP053618|5035629:5043565|5035629_5036217_+|WP_006388149.1|DBSCAN-SWA
MTTTLTAVCSHEEDVKKSRFIAHAAPVATVDEAMAFFAAHSEPEATHNCWAYRIGQEYRFNDDGEPGGTAGRPILQAIEGQGMDRVAVLVVRWFGGVKLGAGGLVRAYGGCAANCLRNGPRTEIVDLATVACACGFAELPLLKSRLAQAGAVIVQEDFSADGVALRFTVPRGAVADLEMTAANITRGRSAWEQLA
>NZ_CP053618|5035629:5043565|5036250_5036625_-|WP_006388150.1|DBSCAN-SWA
MSIVELTKDSFQEAITPDGTLIVDFWAPWCGPCRGFAPVFEQAATEHPDVTFAKVNTDVEQELAGALGIRSIPTLMVFREKVLLFSQPGALSGGQLNELLAKIKEVDMEKVHQEIAAAQDSQDA
>NZ_CP053618|5035629:5043565|5041997_5042756_+|WP_020927471.1|DBSCAN-SWA
MRILVSNDDGYSAPGLEALVKALQGLGDLTVVAPETNHSGASNSLTLNRPLSVRTASNGFIAVNGTPSDCVHVALTGLMDARPDLVVSGINNGANMGDDTLYSGTVAAASEGYLFGIPAIAFSLAEKGWEHIDSAARAARMVVERHLAQPLAAPVLLNVNIPSRRFEDMHGFQVTRLGKRHPSQPVVRTTTPYGDPVYWIGPVGQAADATPGTDFHAVAQGMVSVTPLRLDLTQHSQLDEIRTWAEPLCVDA
>NZ_CP053618|5035629:5043565|5040066_5041098_+|WP_006388154.1|tRNA|DBSCAN-SWA
MIILGFESSCDETGVAAVCTERGLLAHALHTQIAMHQEYGGVVPELASRDHIRRVVPLTHQVLQEAGLEMSDIGAVAYTAGPGLAGALLVGASVAQSFAWSRHLPAIAIHHLEGHLLSPMLADPRPDFPFVALLVSGGHTQLMRVDGVGRYELLGETLDDAAGEAFDKSAKLMGLGYPGGPALARLADQGDAARFDLPRPMLHSGDLDFSFSGLKTAVLTRVKAAEQDGGLDEQTRADLAAATQAAIVEVLAAKSIRALKQTGLRRLVVAGGVGANQLLRARLAAALKPLKAQAYFPPLSLCTDNGAMIAFAAAERVKAGLVTLDPDAHGFTVRPRWDLAEIG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006388149.1|5035629_5036217_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	1.2e-19	36.8
WP_006388150.1|5036250_5036625_-	thioredoxin family protein	V9SJ74	Achromobacter_phage	1.9e-10	27.8
WP_006388151.1|5036822_5037845_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_054438380.1|5038223_5038580_+	VOC family protein	NA	NA	NA	NA
WP_006388153.1|5038664_5039957_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	5.4e-65	36.3
WP_006388154.1|5040066_5041098_+|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.4e-92	51.6
WP_006388155.1|5041167_5041809_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_020927471.1|5041997_5042756_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.5e-67	51.6
WP_020927472.1|5042800_5043565_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.3e-31	45.2

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_CP053618|6218792:6293539|DBSCAN-SWA
GTCAGGCCGCGGCGTCGCGGACTTCTCCGCGCTCGGGCTTTTCGGCCGTCCCTTCCTCGTCGGCGTAGATCAGCAGGGGCTTGCCCTCGCCTTCGATCGCGCCTTCGTCGAGCACCACACGCTTGACGTTGCCTTGCGACGGCAGGTCATACATGGTGTCGAGCAGGGCCTGCTCGATGATGGAACGCAGGCCGCGGGCGCCGGTCTTGCGCTTGAGCGCCTTGCGGGCGATGGCCTTGAGCGCGGCGGGCCGCACGTCCAGCTCGGCGCCTTCCATGGCGAACAGCTTCTGGAATTGCTTGAGCAGGGCGTTCTTGGGCTCGGTGAGGATCTGCACCAGGGCAGCTTCATCGAGTTCGTCCAGCGTGGCGACCACGGGCAGGCGGCCGACCAGCTCGGGGATCAGGCCGAACTTGATCAGGTCTTCGGGCTCGACTTCGGAGAACAGCTCGCCGACGCCGCGCTCGGACTTGGCGCGCACGGAGGCGGAGAAGCCGATGCCGGACTTTTCGGTGCGGTCGCGGATGACCTTTTCCAGCCCGTCGAAGGCGCCGCCGACGATGAACAGGATGTTGGTCGTGTCGACCTGGACGAAGTCCTGGTTGGGGTGCTTGCGCCCGCCCTGCGGCGGCACCGAGGCCACCGTGCCTTCGATCAGCTTGAGCAGGGCCTGCTGCACGCCCTCGCCCGACACGTCGCGGGTGATGGACGGGTTGTCGGACTTGCGGGAAATCTTGTCGATTTCGTCGATGTAGATGATGGCGCGCTGCGCCTTCTCGACTTCGTAGTTGCAGTTCTGCAGCAACTTCTGAATGATGTTCTCGACGTCTTCACCGACGTAACCGGCTTCGGTCAGCGTGGTGGCGTCGGCCATGACGAACGGCACATTCAGCATGCGCGCGAGCGTCTGCGCCAGCAACGTCTTGCCCGACCCGGTGGGGCCGATCAGCATGATGTTGCTCTTGGACAACTCGACTTCGTCGCCCTTGATCTCGCCGTGGCGGATGCGCTTGTAGTGGTTGTAGACGGCCACCGCCAGCATGCGCTTGGGCGAGGTCTGCCCGATCACGTACTGGTCGAGGAACGTCTTGATTTCAGCCGGAGTGGGCAGTTCGGAACGAATCGCCGCGCGCGCGGTCGCCTGCGCTTCCTCGCGGATGATGTCGTTGCACAAGTCTATGCATTCATCGCAGATGAATACCGACGGACCCGCGATCAGCTTGCGGACTTCGTGCTGGCTTTTATTGCAAAACGAGCAATGCAGCACTTTTGCGTCTGCCGATCCCTTTTTTTCAGGCATATGTAGTCGTATCTCAGGTAAAGAAGCGCCGGACCGGGTAAAGGGCCCGGCGCCTGCGCTTACTCAAACAAGGCGGCAGCGGATGGGACTCAGCCGGGAAGTCAGCCTTCCGAGCGGGAGGTCATCACCTTGTCCACCAGTCCATACGATACCGCATCTTCGGCGGACATGAAGTTGTCACGTTCCGTGTCCAGGGCGATGCGGTCGATCGACTGGCCGGTATTGTCGGCCAGGATGCGATTGAGACGCTCGCGCAGGTCCAGGATCTCGCGAGCCTGGATCTGGATGTCGGAGGCCTGCCCCTGGGCGCCGCCCGAGGGCTGGTGGATCATGATGCGCGAGTTGGGCAGGGTGAAGCGCTTGCCCTTCTTGCCAGCCGCCAGCAGGAAGGCGCCCATGCTGGCCGCCAGGCCGGTGCACAGGGTCGACACGTCCGGCTTGACGAACTGCATGGTGTCGTAGATGGCCATGCCCGCGTACACCGACCCGCCGGGCGAGTTGATGTACAGGGAAATGTCCTTGTCAGGATTCTCCGATTCCAGGAACAGCAACTGGGCCACGACCAGGTTGGCCGTCGCGTCGTTGACCGGGCCCACCAGGAAGATGAGCCGCTCGCGGAGCAGGCGCGAATAGATGTCGTAGGCGCGTTCGCCGCGCCCCGACTGCTCGATCACCATGGGAATGTAGCCCAGGCCGGTGGGGGTCACCGACGACCCGCCATTCATTGCCGCATAGAAATCGGTGAATCTCTGCATAGTGTTACGCCATCCCCATCAACTGATCGAAAGGCACCTTTTCGTCGGTGACCTTGGCCTTTTCCAGAACGTGCGCGACGACGTTGTCTTCGAGCACGATCGCCTCGATTTCAGCACGACGCTGGCGGTCGGCCAGGTAATAGCTGACAACCTGGGCGGGTTGTTCGTAGTTTTCCGCGAATTCCTCGATGCGGGCGCGGACCTGTTCCGGCTTGGCCTGCAGCTGGGCTTGCTTGACCAGTTCGGACACCAGCAGGCCCAGGCGCACGCGGCGTTCGGATTCGGTCGAGAAGGCCTCGGCCGGGATCGGCACGGACTCGGCGTTCGGCACGCCACGCTGCTTGAGCTCTTCGCGGGCGGCGGCGATGCGGCTTTGCACGTCGTTGTCGACCAGCGCCTTCGGCACGTCGAACTTGCCGGCTTCGACCAGGGCGTCCATCACGCTGGCCTTGGTGCGGCCTTGCGAGCGCACCTTGACTTCGCGTTCGATGTTGCTGCGGATGTCGGCCTTGAGCTTTTCGATGTCGCCTTCGGCCTGGCCGAGCGACTTGGCGAATTCGGCGTTCAGTTCGGGCAGGACGCCTTCGGCCACTTCCTTGACGGTGATGGTGAATTCGGCGGTCTTGCCGGCGACTTCCTTGCCTTGGTAGTCATCGGGGAACTTGAGCGGGAAGACCTTGCTTTCGCCAGCCTTCAGGCCGCGGGCGGCTTCTTCGAATTCCGGCAGCATGCGGCCCTGGCCGAGCACGAAGGGGAAATCTTCGGCCTTGCCGCCGTCGAACGGCACGCCGTCGATGGTGCCGGCGAAGTCCAGCGTGACGCGGTCGCCGTCTTGCGAGGCGCGGCCTTCACGGGCTTCGAACGTGGCGCGCTGCTTGCGCAGGACGTCCAGGGTCTGCTGCACTTCGGCGTCGGTGACCGCGGTTTCATAGCGGGTCACGGCCAGGGCCGACAGGTCCGGCACGGCGACTTCGGGGTAGACCTCGAACGTGGCGGTGAAGGCCAGCGTGTCTTCGCCGACGCCTTCCGTCTTGGGTTCCAGGTTCGGGGCGCCGGCGACGCGCAGCTTGGCGCCGTCGACGGCTTGTTCGAATGCACGGCCGACCTGGCTGTTGATCACGTCGTAGCGGATGCCGGGGCCATGGCTGCGCTCGAGCATGGCGAGCGGCGCCTTGCCGGGACGAAAGCCAGGGACCTTGGCGGTGCGGGCCACGCGCTTCAACTGCGCCTGGACTTCCTTTTCGACGTCGGCCACCGAGACGGCCAGATCAACACGGCGCTCGAGGCCGGAGAGGGTTTCAACCACAGGCTGCATTAAAAGACCTATTTTCCGAAAGATATGAGATGACGGGCGGATAAACGCGGCATTTTACCGGAAACTTCCGGACCCCTGACGCAAAGGGGCGCGAGCACCCGGATAAGCCCGGATGCTCGCGCCCCGTTTTCCACCCGGAAAGGGCGGCAAATTGCCCGCCAGGGCGCTTTACTTGGCCTTGGCGATGCGATCTTCGATGTGCTGCGCGCGCTTGGCCGAGGACGGGTGCGAGCTCATCATATCGCTCTTGCCGCCGTCCAGCTCGGCCAGCTTCTGGAACGCCGTCACCAGGCCGCGGGTGTTCAGCTTCTTGGCCTGCAGCTGGTCGAACGAGTAGTCGTCGGCGGCGCTTTCCTGCGACTGCGAGAACTGCGCGTTGATGAACTTCTCGGTCAGGTCGCCCAGCTGCGACGAGTTCAGGGCGGCGACCGTGGCGCCACCGGCGGCGCCGGCGGCATCGCGCGCGGCCGAGACCGTGTAGGCGGTCTGCATGGCCTTCTTGCTGTGGCCCAGCGCCACGTGGCCGATTTCATGGCCGACCACGCCCAGCACTTCGTCGTCGGTCATCATGTCCATCAGGCCGCTGTAGACGCGGATGCAGCCGTTGGCCATGGCCCAGGCGTTGACGTCCTTGGTGATGTAGACCTTGTAGTTGGCCTTCTGGCCGTTGACGGTGCCGCCCAGCTGCTTGGCGATCTTCTGCAGGCGCACGTCATACTTGCTGCCCGGCGCGGCGATCTTTTCCTGCGAATCGCTCTGCGCGCAAGCCTTGTCGGACAAAGTCTTGATTTCGGCATCGCTCAGGGTGGCGGCCTGCACCACCTTGCTGCCGGCGCCCACCAGTCCCCCGATATCGAGGGCATGCGACGCGGAGTAAGGGGCGAGAGCAACGGCCAGCGCGGCAACGGTGTAGCGGATCTTCATGAAAAAAACTCCTCTTGACTGACTCGGGTGCGAGTGAGGCCGCAATTCTATATACGCCCAAAGCTCTCAAACCGTTTCGCCACAGAGTTTCGCAAATGCGAACTTCACTTACACAAAAGGCATGCAAAAGACTCCTTACCGTGGTAAGTACCGCGCCTGCGACGTCAAACCGTCATCAAAAACAAATACCGGCGCAGCCCGGCGTTGTTAGAATTGCCGCCGCAGTTTTTTCCGCACTTCCTCATAACGGCTCGCAACCACCATGACCCCCAACACCCCTCCCCGCCTGGGCCTGCTGCCCAGCCTGATTTTCAGCTCGCGCTGGCTGCAACTGCCGCTTTATCTGGGACTGATCGTCGCCCAGGGCGTTTACGTGATGCTGTTCCTGAAGGAACTGTGGCACCTGCTGACGCATGCCACCAGCTTCGGTGAAATGGAGATCATGCTGCTGGTGCTGGGCCTGATCGACGTGGTGATGATATCGAACCTGCTGGTCATGGTGATCGTGGGCGGCTACGAGACCTTCGTGTCGCGCCTGCGCCTGCAAGGCCATCCGGACCAGCCGGAATGGCTCAGCCACGTCAACGCCAGCGTCCTCAAGGTCAAGCTGGCCATGGCGATCATCGGCATCTCCTCGATCCACCTGCTGCGCACCTTCATCGAGGCCGGCACGCTGGGCACCCCCAATGCGCGCTTCTCGGAGGCGGGCGTGATGTGGCAGACCATCATCCACGCGCTGTTCATCCTGTCCGCGCTGGGCATCGCCCTGGTCGACAAACTGTCGACGCCTTCGCATCCCAAGCATTGAGCGCCCGGCGCGCCGCAGCAAAAAGAAAAGCCCCGACACTCGCGTGCGGGGCTTTTTTCATTGTGGCGCGCCGCCAGGGGCGCGCCACGGACCTGGACTCAGGCGGCCACCTTGATGTTCTTGGCGCTCGGGCCCTTGGGGCCGGTACCGACCTCGAACGTGACCCGTTGGTTTTCCTGCAGCGACTTGTAGCCTTCGCTGCGGATTTCCGAGTAGTGGGCGAACAGATCCTTGCTGCCGTCGTCGGGCATGATGAAGCCATACCCTTTTTCGGCGTTGAACCACTTGACGATGCCGGTTGCCATGGAATTTCCTCGAACCTAAAGAAGCGATTGCTCGCGGGGCGCCAGATGATCAAGGATGGGAGAGGAAAGCAACGCAGCACCACTGACCGCGACAAGTTGAACGCAGACCGCGTCTCTTGAAAATCTCGCTGGACCCAGTGTATTGGCGAACCTCGAAAAACGTCAAATAGACGATCATCGCAAGCGTCGCGCCCTGCCCGCGGCGAGGCCGCGATCGCTTTTTTTCAACTCGCCATGCGTCGATACAGGCAGATACGCTCGCGCGCAAGGCATGCCGCGCCGCCGCCCTGCCTCATCCGGCAAAGCCGCCGGCGTCCAGGAACTCCTGCTCGGGCTGCGTCGTCTGCCGGCCCAGCGCGGCGTTGCGATGGGGGAAGCGGCCGAAGCGCTTGATGATGTCGCGATGCAGGACGGCCCAGCGCACCGCGTCGGCGCCCAGCGGTTCCATCAGCGCCACCGCCCGGTTCTGCGCGGCGACGGTTTCCGCATGCTCGAAGGGCATATAGAAAAACTGGCGCAGCACCGGATCGACGGCCAGATCGTGGCCGGCGGCAATGGCGCGCTCGGCGAACACCAGCGCCAGCGGATCGGTGGCGAACATGTGCGCGGTGCCACGATAGGCGTTGCGGGGATACTGGTCCAGCAGGATCATCAACGCCAGCGCCCCCTCGGGCTCGTCCATCCAGGCATCGAGCTGGCGTGCCGCCGCGGCCATGTGGGCCGGGCCGCAATGCTGGCGGAAGCGCTCATCGAAGGCCGCGTCCTTGGTGAACCACTGCTGCGGCCCGGCGTCGCGCCAGAACGCCACGATGTCCGCCGCGCGCAGGGAAACAGGTTCTTGGCCAGGTTGGGTCATGGAGATCATCCTCGATCGATTGCGGGTGCGGGGTGCGGGTCCGCCGCCAGGCGGGCGGAAGGACGGGGAACTGGCGCAAGGATACCGCGAGCCAGGAACACTGGCAGCGACTGCGGCGGCCCCGCCAAGAGGCCACAGGCGCCGCCGGACAGCAAAAGGGCTCCCCGATGGGGAGCCCAGATGCAAAAAAGCCCCCGAAGGGGCTTTTCCGAAAAGTCAGAGCCTTACAGGACCTGAATCTTCGTGGCTTGCGGGCCCTTGGGGCCATTGGCCGTCACAAAGCTGACGCGCTGGTTCTCTTCCAGAGACTTGAAGCCCGAGCCCTGAATTTCGGAGAAGTGAGCGAACAGATCCTTACCACCCGCTTCCGGGGTGATGAAGCCATAGCCTTTTTCCGAATTGAACCACTTAACGACGCCGGTTTCCATACTGTATTTCCTAGAGATAATGGGCAAATGCCCGGAGGTCACGAATCAATCAAGGAGGGGACAGTAGAACAATAACGCTGAGCCGGAAAAGGCACGGCACTGAACGAAAATCGCAACGCTTGTGATCGTGTGCCGACACTATCGTTATGTTCCCCTCACAAGTCAACATAATCCTAAAAAATACGTGCCAATAATGCAACAAAGAGAAACTGCGAACAAAATTTACACGTTTTCATAGGCAAAAAGAAGGCCTGCATAGGTGTAAACACCCACGCATCATAAAAAAACAATCAAGGCTTATATAAATGCCATCAAAGGGCGTCGCTCACACATACGCCGTTTGGATGGCACTTTGGTTTGCCGTCAGGCTTACTCTTCGATAGGTAAACCCAACAGATCGAGCGCCGCGTTGAAAGCTTCGGGGCCCGAGCAAAGGAAAACCGCCACGTCGCCGGGATTCATATTCTCCAGGACCTGGTCGATTTGGTCTTGCGCATTATCAACATTGTCGACACCAGCGGCGTGAATGTCCGCGCCGGCTTCGACTTTCTCGCGGGGCACGAGGTCGGCGATCGCCTCGAGATCGTCCATGCCGGTCACGACATAGGCGCTGATGCTCTCGCCATCCAGCGTTGTGTGCAGCTCAACGCCGCCCGCCACGTCGGCAACATGCCGACTCAGTATTTCCATGATCACTCTTCCTAGACTTGCGGGCCGGGCCCGCCTGGGCGCGCCCGCACGGGTGCGCACACGCCCAGGCGCGACTATAACAGCCTTATGCTAAGGCTTCCTGACAGCCGGCCCCAAAGAGCGGCGGGCGGCGCCGGAGGTGGCCGCCACGCTGCGGCTGCGCACGCCGGCGGCGGCCAGCGCGGCCAGCAGCGGCTTCTGCGCATCCAGGAAGGCGGCCTTCTCGTCGTCCGCCAACTTGCACAGGAACATCTGCGCCAGCAACTGCGTGCGGCGAGCCTTGCGATTGTCGGCCTCCTGGGCCAGCCAGGCGGCCACCCAGTCGGCGGCCGCCTGCGCGTCGCCCTGGTGCTTGACGTGCCCCAGCAGGTCGAACACGGTGACGCCGGCGATGGCGCCGTCCTCGGCGCGCGTCAGGAAGAGCTTGGCGGCCTGGCCGCTGTAGCCCGGGACCAGGGCAATGCAATCGCGCTCGGCGGGTTTCTTCATGGGTACTGCCTGTATCGGTTATCGGTAACCCTGCAATGTAACCCGCGCCCGCCGCTGTCGCGTGGGCGCCACGGAACTCTGCTATCGTCGGCCTGTTTTTCCCCAACTCTACGGCGGACATCATGCAACGCGATTTCGATCTGGTCGTCACCATCCTGGGAGCCCTGCGCGACGCGCCGGGCCCCAACCTGAGCACCCATGACATCAAGGAAGCGGCCCTGGCCCACGAACAAGGCCTGCAGTTGGTCGCGCACCACCTCGACCTGCTGGCCGACGCGGGCCTGGTCAAGCAGGTCAGCGAAACGGCGGCGACCGCCGGCGATACCCGCTGGCGCATCACCTGGAAGGGTTACGACGCGCTGGAACAGGACGAAGAAGACGACGACGAGGATTTCGACGCCGAGGAATGAGGCGCGCCCCGGCCCTTGCGACGCGGCCGGCGGGCGTGTCATCGCGCCCCGCCGGCGGCCCGGCGGCCACGCCCGGCCAGGTTCCGGAACGGCTCAGTGGCGCCGCAGGATGCGCCGCGTCAACAATGCGGCCGCGGCGCCGATCACCAGACTGAACATGAAGGCGGCAACCGCGAGCATCGCCGCCTGATCGCCGAAACCGGCAGATCGCGACACCACCACCACCACAGCGCAGACCGCCGCGGCCCATACCACCACGCCCGCGAGCACGCGGCCCGGTGTGCGCAACCGGCCGCACAGCGACCCACCCACGAGCGCCGCGGCCACCATGGCGGCCATGGACCAGAACAGATATTCGTAGTGCATGCGGACGGACTCCCCTGCGGTATTGAGGCGAGCGCATTATAGGCGGGCGCGCCGCCCATCCGTCCCCGAGATCCAGGACGTGAGCCGCCGGCGCCCGCCTCAGGCCTGCGGCGCGACCGCGACGGCGCTGATTTCCACCAGCGCCCCATAGTGCAATTCCCGTGTCGGCACGATGGCGCGAGCGGGGCGGTGATCGCCGAAGCTGCGTTCGTAGACGCCGTTCACCTCGTTCCACATGCCAACGTCCGGGATGTACACCGTGACATTGACCACCGCGGACATCGATGTCCCCGCGGCTTGCAAAATGGCCGCCAGGCTGCGCAGCGCGGCCTCGGTCTGCGCGGCCACGCCTTGCGCGAGGCGTGGCGGCTCGCCGGGCTGGACGGGCGGCAGGAAACCCAACTGCCCGGAAACGAAGACAAAGCCATTGGCGCGCACGGCCTGCGAATAGTGGCCGGCCGGCGGCGTCGCATGGGGGGTGGATATGATGTCCATCTCGACTCCTGGAGGCTGCGGCCGGGCTACCAGCCGCGGAAACGTTGCCATTGCGCCACGACCTGGCGATCGCCGCTACGCACCACGGCGTAGGCGTCATGCTGGGCGCAGGTGGCGCAGGCGTGGTTCGGCACGATCCGCAGCCGGGTGCCCAGCGGCAGATCGGGCAAGGTGGCGCCGCTGCCCGCGCGCAGCTTGATGATGCCCTGCTCCTGGTTGGTCTCGGCCAGCAGCAGGTCGGGATAGACCTGGCCATCCGCGTCGCACACCAGCCCGTACAACTGGTCCACCGGCTGCCGGGCCGTCCCGCGATCGCGCGACATGGCCATCCAGCCGGCATCCACCAGGATCCAGCCCTTGTCGGGCTGGTGGCCGATCACCGTGGTCAGCACGCTCGCGGCGATGTCGTCCACGGCGCACACGCCCAGTCCCGCCATGACGAGGTCGAAAAACACGTAGACGCCGGCGCGCACTTCGGTCACGCCCTCCAGGTTGCGGGCGAAATGGGCGGTGGGCGTGGAGCCCACGCTGACCACCGGGCACGGCAGGCCGGCGGCGCGAATCGTTTCGGCGCAGCCGACGGCGGCCAGGCGTTCCTGCTCGGCCATGTCGGCGATCGCTTCCACGCTGCGGCAGCCATAGGACTCGCCGGCATGGGTCATGACGCCGCGCAGGCACCCGGCGGCATGCAGTGTTCGCGCGATTTCCAGCAACTGTCCGGCCTGGCCCGGCTGCACCCCGGCGCGGTGGCCATCGCAATCGATTTCGATCAGCGCCGGAATCGCTGCGCCCTCTTCGAGCGCGCGCGCGGCCACGGCCTGCGCCGCCTCGACGCTGTCGACCACGACGGTCAGGTCGACCCCACCACGCCGCAGCGCCAATACCCGTTCGAGCTTGGCGGGCGCCACGCCCACGGCGTACAGCAGGTCGGTCACGCCCGCCGCCGCGAACTGCTCGGCCTCCTGCAGCGTCGACACCGCCGCCGGCCCTTCGGGTCGCGCCATGACGCGACGCGCGACCTCGATCGATTTGGGCGTCTTCAGGTGCGGACGCAGCTGCACCCCATGGCCGGCCATCAGGCGGTTCAGGCGCTTGATGTTGCGTGTCATGCGGGTTTCGTCCAGCAGCAGGCAGGGCGTATCCAGCGTATCCAGGGTGACGGAGGCAGTGGTCATGGCGATATCGGTGAAGCTGAAACGGGCGCGCGGGAAGGAGTGCAACGCGGATGGCGCCCGGGTATCCGTCCGCAGGTTCGCAGTATGGCGCGCCAGGGCGCTTGCGTGTTTAATCAATGCTTAATCAATCATTAAGGCGATTCTGAATGATCACCACGGATGACCTGCGCTTTTTCCTGAGCCTGGCCGCCACCAGCTCGTTGGCGCAAGCGGCGCGCGCGCTCGACGTGACGCCGCCCGCCGTGACCCAGCGCTTGCATGCGTTGGAAAAACGCCTGGGCGTGCGCCTGGTCAATCGTTCCGGGCGCGGCACCGCGTTGACCGACGAGGGCCGCCTGCTGGCGCTGCGCGCCGGGCAGATCTGCGGGGAACTGAACGAGCTGGCCGATGAGCTGGCGGGGCGGCGCGGCGTGGTGGCCTGCCATCTGCGCGTTGTCGCGCCGCTGGGATTCGGCCAGCGGTACGTGGCGGGACTGGTGGCGGAGTTTCGCCAGCACAGCGACAACGTGACCGCCAGCCTGGTGCTGTCCGACGGTCCGCCGCGGCTGGCAAGCGATGACTGGGACGTCATGGTTCACATCGGCGAGCTGCGCGATTCCACGCTGGTGGCGTATCCCCTGGCGCCGAACCGGCGCATCCTGTGCGCGTCGCCCGCATACCTGGCTCGCCACGGGGCGCCCGCCAAGCCCGAAGACCTGCGCGACCACGACTGCATCGCGTTGCGTGAAAACGAAGAGGACGTGACGCTGTGGCGCTTCAAGCGCGGTCGCGGCCCGGTGGTGGGCGTGCGCATTGCCCCCGTGCTATCGAGCAATACCGGGGCCACGGCGGTGGCCTGGGCGCTGGCGGGGCATGGCATCGTGGCGCGATCGGAATGGGATGTGGCCGAGCACGTGAAGCGCCGCGCGCTGGTGCCGTTGCTGCCGGGCTGGAGCCTGCCCGAGGCGAATGTGGTGGCGCTGGTGAAATCACGCCAGGACCTGCCCGCGCGCACCGCGGGCTTTCTGGCCCACCTGCGCGAAGCCTTTGCGGCCACGCCATGGCGCGACAAGGGCCAGGCGTAGCGATGTGAAGAAGGGGAACCAGCGGGAGGCGTGTTCATCCGACGCGGCGCCGGAAAGTCGGTGGACTCTGCAAAGCCGTGCCTGCCGACGCGAGCCGGATGAACGTTCGCAGGATGCCAGATCGCGGGACGCCCGGGGCAGGCGCTTCCGATAAATCGGACTCCTCGATCCCCCCGCCACACTCAGTCGAGCATGGCTTCCGCTTCGATCTCGACCAGCCACTCCGGCAACGACAGGCCGCTGACGATGATCCAGGACGAGGGTGGCGGATCGTTCGGGAAGCGGTCGCGCAGCACTTGCGCGATCGACTCCTGGTCCTCGCGCGCCGTTTCGCAAATGTAGATGCGCAGCATGATGACCTGCGCCAGTGTGCCGCCGGCCGCCGCCAGCACGCGTTCGATATTGTCGATCGCCGCGTCGGCCTGTTCGCGCAGCCCTGGGCTGACCGTGCGCTCCTGCGCATCGACGCCGACCTGGCCCGACAGCAGCATGCGGCGCTGGCCGGTCACGATCACGGCCTGGCTGAAGCCATATTGCACCGTATTGAAGACAGTATCGGGATTGACGACGGTTCGGGACATCTGGATTCTCCTGGTGGGCGGCGCGCCCCGCGGCGCGGCGCTTGCGCCATTCTAGAGGCGCCCGCCATCAGGCGGCCGCGGGCGCGGGCCGCGCGCCACGCGCCGCGTACACGGCCACCAGCAACACCACCGCGCCCGCGCCGACCGCGGTCCAGAAGCCCGCGCCGACGCCATGATGATCCACGATCCAGCCCGCCAGCGCGGCGCCAGCCGCGACGCCCGCGCCCAGGCCCGTCACCAGCCAGGTCAATCCCTCGGTGAGACGGCGGCCCGGCACGGTGCTCTCCACCAAGGCCATGGCGATGATCATGGTCGGCGCGAACGACAGGCCAGCCAGCAAAACGCCCAGGGACAGCGTGAGCAGGTCGCCGACCCACAGCAGCGGCAAGGTGGTGAAGGCGGTCACGCTGGCGGCCACGGCCAGCAACCGCGCCAGCGGCGTCTGGAACTTGAGCACGCCGAACGCCAGGCCGGCGACGCACGATCCCAGCGCGTAGGCCGACAGCACCATGCTGGCCCCGGCCGGCAGGCCCTGCTGGCGCGCGAAGGCCACGCTCATCACGTCGATGGTGCCCACGATGACCCCCATGGCGGCCATCATCGCGGTCAGTTGTCGCATCAGCGGCACGCCCAGCACCGAGGTCTCACGGCCCGCTTCGCGCGGCTGCACCGCCGGCGCGGTGGCACGCTGCAGCACGAAGGCGGTGACGCCCAGGCCCAGCAGCAGCGCCGCGCCGAGCGGGCCGGCTTCGGGGAAGAGGATGACGCACAGGCCCACGGCCAACGGCGGGCCGATGATGAAGCTCAATTCGTCCAGCACCGATTCGAGCGCATAGGCGGTGCGCAGTTGCGGCCGGTCGCGATAGATCTCGGTCCAGCGGGCCCGCGCCATGGCCGGCATGCTGGGCAGGCTGCCCGCCAGCGCCGCGAACACGAACAGGGTCCAGTCGGGCGCCTGCAGGCGCACGCAGGCGGCCAGGCCGATCAGCCCCGCCACGCTGGCGCCCGCCGCCAGCGGCAGCACCCTGCCCTGCCCGTGGCGATCCACCAGGCGTGAAATGCGCGGCGCGAGCAGCGCCGTGGCCAGGGCGAAGGTGGCCGCGACCGCGCCCGCCAGGGTGTAGGCGCCCCGCACTTGCGACAGCATGGTGATGATGCCGATGCCGATCATCGGCAGCGCCAGCCGCGCCACGGCGCATGCGGCGACAAAACCGGCGGCGCCGGGCGCCTGGAACAATTCGCGATAAGGATTGGACACCCGAAACCTCTGGGATGTTGCGGGCCGGCGACAGCCAGCCGGAGAAATTTACATACGTGACGTATGTGAGATGGTATTCACATGCATGGCGCATGTCAATTAACATACGACCCGTATGTCATTGGAGCCAGCCATGTCGCGATCGCGCGCCGAGATGATCGAGGAAACCCGCGGAAAACTGTTGGCGACGGCGCGCGAGTCGTTTCGCCGCGCCGGTTACGCCGGCACCTCGATGGATGACCTGACCGCCGCCGCCGGCCTGACCCGGGGAGCGTTGTATCACCATTTTGGTGACAAGCAAGGTCTGCTCGCCGCGGTGGCCGCGCAGATCGACGCCGAGATGGAGGCGCGGCTGCAGGCCATCTCGCGGGATGCGCCCGACGCCTGGACCGCGCTGCGCGAGCGCTGCCGCGCGTATCTGGAAATGGCCGCCGACCCCGAGATCCGCCGCATCGTGCTGCAGGATGCGCGCGCCGTGCTGGGCCATGCCGGCGCCGCCGCCCAGGAACAATGCACCGCGTCGCTGGGCGAGTTGCTGCAGGACCTGATGGACCAAGGCGTGATCGTCGCCGCGCCCCCGCGCGCGCTCGCCCGGATGTTGCATGGCGGCCTGGCCGAAAGCGCATTCTGGATCGCCGAGGACGATGGCCCGGCGCGCCTGGCGCAGGCCTTGCAGGCGCTCGATCTGCTGCTGCAGGGCATGCGCCGGCGCTGACCGGATCGATGCCCGTGGGCGGCCCTCGCGGCAAACGCCATCGTCGCGCATAATGCGCTCAGCGCGCTCAGTGCCCCACCGGCCCGCGCCCCTTCCCTGAACCCGGATCCACGATCATTCGAGATGAAGCTTTTGCGTCATTACGCCCTGGCCGCCCTGCTGTGCGGCGCCGTGCTGCTGCCGGCCGCCGCGCCCGCCCAACCGCCCGCGCCGGACGTCACGCAGGCCCTGGTGGGCAAGTGGCGGCACCAGACCATGCTGCGCACCGTCGACGGCAAGGCGCAGCCGCCCCAGCCCTCCGGCGGCGCGGGCGTGGTCGAGTTTCGCGGCGACGGCACCTGGTCGATGCAAGGCCCGGACATGGTTTCCAGCGGCACCTACCGATGGCTCGATGCCAAGCGCATCGAACAGACGCTGGAGCAATCCACCAGCAAGCATGAACTTGGCGTGGCCTCCATCCGCTACGTGAAGATCCAGGGCGATCACCTGAGCCTGACGCGGGTGCAGGACCGCAGGGAAATGGACAAGCTGATGCCGCCGCCCGGACCGAACGTGCGCCGCCCCGACCAGTTGATCGTCACCAACGTCTTCACCCGGTTGCCGGCGGAGCCGAATCCATCCGCGCCCGCGGGCGGCGCGGGTCACCGCTAGGCCAAACGCGGTATGGAAGGATGAGACCGTCTTTGCTACGCTGAGTCATCCCCATGGAGGGCACCAGGCCATGAAACCCAAGATCCGCGTGCTGCGCGTCCAGCCGTCGTCGATGTCGGCCCGCTTCGCCTTCCTGGCGATCGCGCTGCGCTGGTCCTTGGGCGCGACGCCCCGGCCGGCGCGCCTGCGGATCGGCCCGCACGACCTGGCGCCGGTCGGTTCCGAGGCGGCGTTCTGGATGTTCGCGCTGCGCCACGCCCTGTCGGCGCAGTCGGTGCTGGTCACGCGGGGCGATCACTGGGACGTGGCGGCGTCGGTCGATGGCGACGTGATCCGCGCCTTCGGCCGCAAGTTTGCACTGCGCCAGTGCCTGTGAAACAAGGCGATTGGCGCGGGCGGCTAGAACTCGGGCAGGTCGAACACCGTATGCAGGGTGGAACTGGGCGCCGGCACGGAAGCCAGATGCTCGCGGCCGTCCTCGTCGGTCAGCACCCGCACCGGGCGCGAAGCCACTGACAGGCCGTCCACGCTGACGACGGTCTCGACGTCGGCGCCGGCCTTGATGGCTTCGATCACTTCGGAAGCCGCCGCGGTCACGGGTTCGCTGACCCAACCGGGCACGCCGCGCTCGGCCAGCCCCCAGCGCACGTAGGCGACATGGCCGGTAACGGCTTCTTTACGAACGGCGACGATCGCGTAAAACGACATCCGGGCCTCCCTCAGGTTTGGTGGCCCGGATCGTATAACAACTTGGCTGATTCGCGATGACAGCCGTCAGGGTTCGATGTCGATGGGCTCAAAGGATTTCACCAAGTCATCCAGTTGTTTCAATTGGGTGAGGAACGGCTCCAGCTTGTCCAGCGGCAGCGCGCTGGGGCCGTCGCATTTGGCGTTCCGGGGGTCCGGGTGGGCCTCCAGGAACAAGCCCGCCAGCCCCACGCCCATGCCCGCCCGCGCCAGTTCCGCCACCTGCTCCCGGCGCCCGCCCGAGGCGGCGTCCAGGGCCGAACGCTGCTGCAGGGCATGGGTGACGTCGAATATCACGGGCCGGTTGCCTGTCACCTTTTTCATGACCCCGAAGCCCAGCATGTCCACCACCAGGTTGTCGTAGCCGAAGCTGGTGCCGCGATCGCACAGGATGATCTGCTGGTTGCCGGCCTCGGTGAATTTCTCGACGATATTGAGCATCTGGGTAGGACTGAGGAACTGCGGCTTCTTGATGTTGACGACGCGGCCGGTCTTGGCCAGCGCCACCACCAGGTCGGTCTGGCGGGCCAGGAACGCCGGCAACTGCAGGATGTCCGCGACCTCCGCCACCGGCGCCGCCTGCCAGGGCTCGTGCACGTCGGTGATCACCGGCACGCCGAAGTTCTGCTTGACCGCCTCGAAGATCTTCATGCCCTCTTCCAGTCCCGGCCCCCGGTAGGAATGGATCGAGGAACGATTGGCCTTGTCGAACGACGCCTTGAACACGTAGGGAATGCCCAGCCTGGTGGTCACGCGCTGGTATTCCTCGCAGGCGCGCAGCGCCAGGTCCTTGGATTCCAGCACGTTGATCCCGCCGAACAGCACGAAAGGCTGGTCGTTGGCGCACGTGATCGAGGGCGAAATGATGACTTCCGGGGCGGTCATGATGGGGCTGTCCTGTAGGGATGAAGCAGGTAATAGTGCGTAATGTACAACCTGCCCACCCCGGTTCCGGCCGCCGCCGCCGCTTTTTTGCCTCGGTCCGGCGACAGGACGCCATGGGGCGCCGCCGCGGCGCTGCGCCGTCCGATCCGCGCGGTCGGGACGAACGCAAGATACACTCGCTGACGGGGGACGATACCCGCGAGCGTATTGACAACGGACTTACGACGACCTGATTCATGGACACCGACACCCTGTCCCGCCGACTCGAATTCCTGCGGCAAGCCGAGAAGCTCAAGGACGTGCTGCGCAGCGCCCGCAGTTCGGGCGGGCGCCAGGAAAGCACCGCCGAACACACCTGGCGCCTCTGCCTCATGGCCATGATGCTGGAGGAAGACCTGGCGGACCTGGATTTCACCCGCATCCTGCGCCTGTGCGTGATCCATGACCTGGGCGAAGCCATCCACGGCGACATTCCGGCGACGCAACAGTCCCCCGGCGCCGGCAAGGGCGCCCAGGAACGGCTGGACCTGCTGCAACTGGCCAGCCCGCTCGATGCCCCGGCGCGCGACCGGTTGCTGGCGTTGTGGGACGACTACGAGAATGCCGCCTCGCCCGAAGCCCGCGCCGTCAAGGCCATGGACAAGCTGGAGACGCTGCTGCAACATAACCAGGGCGCCAACGCGCCGGACTTCGACTACGCGTTCAACCTGGACTACGGCCGCAAGCACACCGATGCCCTGCCGCTGTTCCGCGAGATCCGCCGGCTGCTGGATGCCGATACCGAAGCGCGCATCCGCCAGCAGGCCGCCGAACGCGCCGCGCGGCCCGCGCCCTCGCCGGCCGATGTCGTGCAGCGCCAGTTGGACGCCTACAATGCCCGGGACATCGACGCCTTCATGCGGGCATGGGCGCAGGACTGCGAGTATTACGCGTTCCCCGACACCCTGCTGGCGCGTGGCAGCGCCCAGGTCCGCGAACGTCACCTCGAACGTTTCAAGGAACCCGATCTGCACGGCAGGCTGGTCCATCGCATGGTCAACGGCGACATGGTGGTGGACCAGGAAGTCGTCACCCGCAACTTCGCCGACGGCCGCGGTGAAGTCGACGTCGTCGCGATCTACGAAGTGCGCGACGGCCAGATCGCCAAGGCCTGGTTCAGGCTGGGCGCGCCGCGACTGCACGGCGGGCCCGCATAGCGGCCGCAAGGCCCGGGAAAAGCATGGGATTACTCGACTCGCTGTTCCGGCGCAAGCCCACGCAAGACCAGTTCGCCCGGCTTTTCATCGACGCCGTCCGACAGCGGGGCTACACCGGCACGCTGGACTACAAAGCGGATGAATTCCGGCTGCTTCACGGCGAAGGCTCGTACTTCAACCTGCACAACGCCTATAACGCCTATTGCGAAGCCCGAAGCGGCCAGCGCCAGGGCGCGTTGCAGGGCTATGTCTCGACCCTGCTGACCAGCGACCAGGCCAGGCCGGCCTCGCTGGCCGAGGCCCGCCCGCTGCTGCGGCCGGTGATCCGGGCCCGGGCCATGATCGAGGCGATCCGCATGCACCACCTGCGCACGGACGGCAACGACACCGACTTCCGCCCCGCCCTGCGGCCGTTCGGCGACGACTGCGTGGTGCTGCTGGCGCTGGACCATCCGGAATCCATCGCCACGCTCACCAACGGCCCCGATGCCGACTGGGGCCTGTCGTTCGAGCAGTCGCTGGCCATCGCCATCGATAACCTGCGTGACTCGGCCGACCACTTCGTGGAAGTGGCGCCGGGCGTGCATGGCGGGGCCTGGGAAGACGGCTACGACATCAGCCGCGCGCTGCTGCCGGACATGCTGGAACGCGTCGCGGTCCGCGGGCGTCCGGTGTTCATGATGCCCACGCGGGATCTGTTGCTGGTCAGCGGCGACAACGACGACGCCGGCCTGTTGAAGATGATGGAACTGAGCCAGCAGGTGGTGGCCCACGGCCGCCCGGTGTCGCCATACATGTACCACTATGGCGAAACCGGCGTCGAACGCTACCTGCCGCGCCAGGAGCGCATCATCCACCTGCAGGCGCACCTGGCGCGAGTGCTGGCGCAGGGCGATTACGACGCGCAGAAGGAAGCGCTGGACCGCCTGCACGAGGAACGGGGCATCAATGTGTTCGTCGCCACCTACAATCTGTTCATGCAGAACGACGATTCCGCCACGTCGTTCTCGCTGGCGACCTGGACGCGCGGCGTGGACACCTCCCTGCCCAAAGTCGACCGGCTGGCGCTGGTGCGCCCGGAGGCCAACGACGATATCGGCGAAGTGCGGGTTGTCCACTGGGAACAGGCGGCGCCGGTGCTGGCGCCGTTGCTCGAACCCGAAGATCTCTATCCGGCGCGCTACCGCACCCGGGGATTTCCCAGCGACGCGCAATTGGCGCAATTGCCCGAAGCGGATTGAGCGCAACCGGACGGTCGACCCGTCCGGCGGGCGCATCATCACCTCAGGGCTGCGCTTCCGATTGGCTCACCAGGCGATAGGCGATCGCGCCGATGATCGCGCCCACGATCGGCGCCACCCAGAACAGCCACAGCTGCTCCAGCGCCCAGCCGCCCACGAACAGCGCCGGGCCGGTCGAACGCGCCGGGTTGACCGAGGTGTTGGTGACCGGAATGCTGACCAGGTGGATCAGCGTCAACGCCAGGCCGATCGGAATCGCGGCGAAGCCGGCCGGCGCGCGCTTGGAGGTCGCGCCCAGGATCACGAACAGGAAACCGGCCGTCATCACGACTTCGGTGACCAGCGCGGCAGCCATCGAGTACTTGCCCGGCGAATAGGCGTCAAAGCCGTTGGCGGCGAAACGGCTGGCCTGCAGGTCGAAGCCCTGTTGGCCATTGGCGATCACCGCCAGCACCGCGGCCGCCGCAATGGCGCCCAGCACCTGCGCCACCACGTAGGGCAGGATTTCGCGGGCGGGGAAACGCCCGCCGGCAACCAGGCCGACCGTGACCGCGGGATTGAAGTGCCCGCCCGAAATGTGGCCGACGGCGAACGCCATGGTCAGCACCGTCAGGCCGAACGCCAGCGCGACGCCGGCAAAGCCGATGCCCAGTTGCGGAAACCCCGCCGCCAGCACCGCCGCGCCGCAGCCGCCCAGCACCAGCCAGAAGGTGCCGAAGAATTCCGCGCCGCAGCGCTTGGATAGTGGGTACATGTTTCGCCCTCCGCGATTGAAAACGCGAAGGTAGCGCGGCGCGGGCGTTACGATTTCAAAGCAATGCAAATTCCGCGCGATTCTTGACGTTGCTTGACGATGTCGGCCGGTATCGGGCCGGCCGGCGTCGCGCGAGCCCCGCTCATCGCGGCGTTCTGGGGTCCACGCTCCACAACGCGACGTCGCTGGTCGACACCGCCACCGCGCCCTGGCGCAATGCGGCCGCCACGTCGGCCTGGTTGCAGACGAAGCCCGACGCCACGATCGGCGGCAGTGCCTTCAGGTCCTGCGGCGCCATGTGGGCCAGCATCGGCGCCGGCATGATCTGCACCAGGTTGGGATCGCTCTGCTCCAGCGCCTTGACGCTGCGCGGCCAGGTGGAGCGGTCGGTCACGAACACCTTCTGCATCGTCACCATGCCGGCGCGGTTGGCGCGCTGGATGGTGGCCACACGGGTCGACACCAGGCTCGCCACGCCGATGTCCGCCAGGTATTCGACGCCGCCCTTGTCCTGCGACAGGCCTTCGCAGCTGTCGATATTGACGATGACGTACTTGCCCGCCCGGTTCAGGGCGGAGATCACCGGCGCAAGCCGGCGCAGCTCGACATTGGCGACGATGCCGATCTCGGCCACGCTGCCGACGAAGGCGTTGACCTGCTCCGGTCCGTAGAGCGTGGCAATGACCGGATGCCGCGCCAGGCATGCGCCGAGTGACCTGTCCATGTTATCGCCTGCCTTGATCGTAGGGGCCTTCGTCCGTCAGGCCGAGCTTGCCGGGGTTGAGGATATTGTGCGGATCCAGCGCCTGCTTGACGGCATGCAGCACGGCGAAGGCCGGCCCGAGCGATTCGCGCATGTAGGGCGAGCGCAGCAGGCCCACGCCATGGTGGTGGCTGAGCGCGGCATTGTATTTGATCAACACCGCGTTGGCCGCGTCCCAGGCGCGCCGATACCACTGTGCCCGCTCGTCGACCGCGACCTCGCCGCGCAGCGAAAAATACAGGCAGGCGCCATCGACGTAGGCATGCGACTGGTGCGCCGAACCGGCCAGCGTGCCGGGCACGGCATTGACCGCGGCAACCACCTCGTCGTAGATGGCGGACAGGTCGCTCCAGCGCCCCGCCATCTCCAGCGTGTCCGCCACGAAGCCGGGGCTGCGTTTGAAGCCTTCGGCGCTCTTGCCGGTCAGGTAGCGCGTATCCAGCCAGCGCTCGAACACCTCATTGCCATCCAGCGCCACGCCGGATTCGCGGCAGACCTCTTCGCTGATGCCCATGACCGCGTCGACGATCGGGCGCGGCCCCTCGTCGGCCACCAGCAGCACGTTCAGGTCGGGCCGGTTGAACTGCACGCCGCTTTCCAGCGCGTCGTACAGTCGCAAGGCGGCGGGGTTGGCACCGCGCTGCATGATCTGGCGGCAGGCATCCAGGCCGGCCGCGAAGGTCTCGAAACCGTAGGCGATGGCGCGGCCGTAATCGGGCAGGCGATGCAGCTTCAGGCGGACCCGCACCACCACCCCCAGCGTGCCCTCGGAGCCGATGAACAGCTGCAGCAGGTCGGGGCCCAGCGCCGCGCGCGAATAACCGCCCACCGTGATCAGGCTGCCATCGGCCAGCACCACGTCCATGCCGAACACCATGTCCTCGATCTTGCCGTAGCGCGTGGACAGTTGTCCCGCGCCGCGGCATGCGACCCAGCCGCCGACGGTGCTGATGCCGAACGAGGACGGCCAATGGCCCATGGTCAGGCCATGCTCGCGCTGGATGGCCTGCTCGAACACGTCGCCGAACATGCCCGCCTCGACCTCGACGATCTGGCTTTCGCGGTCAATCCCGATGAAGCGGTTCAACTGGCAGACGTCCAGCACGATGCCGCCGCGCAGCGGCAGCGCCGCCCCGGTGACGTTGCTGCGCCCCGCCGACACGGTGACGGGAATGGCGGCCGCGTGCGCGATGCGCATCACGGCCTGCACCTGCTCCACCGTCGACACCTTGACGATCACCGCGTGCGGCGTGGCCGGGCGGCCGGCGGTCTCGGTCATCATCGAGCCGGCCCACCAATCGCGCGTCCAGGCCACGGCGTCGGCGGTGGTGGTCAACACCTCGTCGGCGGCTGCTCGCAGCGCCTCGACCTGCGCGGCCGATACGGACACGGGATCGCGTTGCAGGCCCGGCTCGGTGCCAGCCTGCGTCAGGCCCGCCGCGTAGGCCGGCGGCGTGTGCGCGCCCACTACGTAGTTGCCGCGGTTGTAGCCGCGCTTGATAGCTTCTTTACTGATCACGAGTCGTCTCCCATTAGTACGGACTTTTCATGCTCGATGGCGGCGCGGTAGCTGCGCACCTGTTGCGCCACCGCGGCGTCGGACAGGCCCAGTTCGGCCTGCAGTATCTTGCCCACGCGTTCGGCGGCCTCGGCGGAGGCGTCGCGCGCCATCAGCCTTGCCCGCATGCGGCGCGAGAGCACGTCTTCGACCGTGGCCGCCAGCTCGTGGCGCACGGCGTACAGCGCCTCGGCCTCGGTGTACGGCAACCCCGGCACCAGCGGCGCCGCCAGCGCCGGCGTCTGCTGCATCAGGTCGCTGACGAAGCGCGCTTCGGTGCCATAGCGTTCGCCCAGGTGCGCGGACAGGCCGCCCGAGGCCACGATGGCCTGCGGGTCGTAGCCGGCCGCGCCCAGCAGGAAGGCGCTGGCCGTGACACAGCGCGCCTTGCGCCCCAGCACCTTCTGCGCGGCGTCGATGGTCTGCTCGGCCATGTGGCGCGAGGTCGTCAGCTTGCCGCCGACGATGGTGACCAGGCCATCGGCCGCGATCCGGATTTCGTGGTTGCGCTTGATCTCCAGCGTCTTGCCGCCCGGCGGCGCGACCAGCGGCCGGCAGCCGGCGATGCTGCCCACCACATCCTCGGCGCGCAGGTCGGTCTTGAGCGCCGAACGCGCCCCTTCCAGCAGGAAATCGAGTTCGCGGCGGGTGCAATGGACATCGTCGAGGTCGCCCGCGTAGTCTTCGTCGGTGGTGCCCAGGTACGAGACATTGCCCCAGCGCGTGATGGTGGCGCGGCGGCTGCGGCCCGGCACCGGGATCGTCACCGTGCAGTCGTTGCGCACCTTCAGCCAGGGCACCGCCACGTGCACGCCCTTGGCGGGGCGGATGTGCAAGGCCTGGGGATCGCCCTTGCGGCTGCCGTTCCAGTCGCGCAGCCAGACGCCGGTGGCCATGATCACCACGTTGGCGCGCACGCGGATCTCGGCCTGCCCGGCCTGCACGATGGCGCCGTCGACCTTGCCATGCGTGTCGCGCGTGACTTCAATGGCCCGGGCGTGGTTCAGCACCGCCGCGCCATGGAACGCCGCGGTGCGCGCCACCGCCAGCGTCAGGCGCGCGTCATCGACCCGCGCGTCGAAATACAGGAAGCCGCCGAGCAGGCCGTCCTGCTTGAAGGTGGGGCAATGCGACAGCACTTCCTCGGGGGTCAGTTTCTGGTGCAGGATGCCCTCGCGCCAGCCGCCGGCCAGGTCGTAGGTCCAGAGCAGGCTCTCGAACGCCTTGGCCAGCCGCTTGTCGAAGACGCCGTCGCGTTCCAGCAACGGAAACAGGAACGGCAGGCGCTGCACCAGATGGCGGGCGTTGCGCCGCAGCCGCTGGCGTTCGTGCAGGGAATGGCGCACCAGGCCCAGGTTGCCCTGCTCGATGTAGCGCAGTCCGCCATGCACCATCTTGGACGACTTGGACGAGGTGCCCGAGGCGAAGTCGTCCTTTTCGACCAGCGCCACGCGATACCCGCGCAGGCTGGCGTCCAGCGCCGCATACGCGCCCGTGATGCCGCCGCCGACGATGAGCATGTCGAAGTGTTCGCCGCCCAGCCGGTCCGCCTGTTCCTGCCGCGCCAGCCGCAACGGTTCGCCGCGGGTCATGCCGGCCCGATCCTTCCTGGGCTTTCTCGATGGCAACCCGATCATGTCCGCAATGCCTCCTGCTTGTCCTGGGAATACAGGCCCGCGTGGGCCAGTTCGGATTCGACGCGCGAATGCCACAGCGCGCGGCGGCGGGCGCGGGCCTCGGCCGCCAGGGTGGGTTGGAATACCGCATCGGTGGCGGCGGTCTGGCGCGCGGCCTGCAACGATGGCCACAGCAGGCCCGACGCCCCCGCCAGGAACGCCGCGCCGCGCAGGCTGGCGCGATCGGCCTCCTGCATGCGGCGGATCGGTATCCCCAGCAGGTCGGCCTGGATGCGCAGCAACGGATCGCTGCTGGACAGGCCTCCGCCAACCACCAGTTCCGACACCTGCACGCCCGATACTTCCTCGTCCGCCTCGATGCAACTGGCCACCGAATGGGCGATGCCTTCCAGGATCGCGTAGGCCACTTCGGCCTGCGTGGTAGCCATGGAGATGCCGGTGAGCGAGGCGCGCGCGCCGGCCGCCATGCGCGGCACGCGCAACCCGGTCAAGGCCGGGATGAATGTCACGCCGCCCGCCGATTGCGCGGTGGCGGCCAGTTCACTGATCTCCTGCGCGTTCCTGAACCACTTCAGCTTGTCGCAGACCCAGTTCAAGGCCGAACCGGTGGTGGCGACGAAGGTCTCGACCGCGAAGTGCGACACCTGGTCCTGGCGCCGCGCCGTCATCGTCAGCGAGCCTTCGTAGCGGCCGCTGTTGACGGGCGCCTCGGGGCCGATGATCAGGTCGACGAAACTGCCCGTGCCATGCACGCACATCGCCTGCCCGCGATCCAGGCAGCCCAGGCCCACCGCGCCCGCGTGCTGGTCGCCGGCCGACGCCCGTATCGGCACGGCAAGGCCCAGGAGGTCCGCGCGCGTCTGGCCGAAATCGTCGGCTTCCTGGCGCAAGGCCGGCAGCAGCTCGCGCGGAAACTCCAGCGCGTCGATCCAGTCCAGGTAGTAGCGGTGCCCGGACAAAACATAGGCGCCGGCCGAGGTGGCATTGGTGGGCGTCGTCACGCATTCGCGGCGGTCCGACATATGCCACAGCAGCCAGGTGTCGACGGTACCGAACGCCAGCCGGCGCTCGCGCCAGGCCTGTGCCACGGCCGGTGAATCGCGCAGGTGGCGCGCCGCCCACAGATACGGCGAACGCACACCGGCCGGGCGGCCCACCTGCTCCAGCAGGCGCGGGTTCCAGGCGGGCGCCAGGCGATCGAGTTCATCGACATAGCGCGTGTCCTGCCACACCATGGCCGGCACCAGCGCGCGGCCCGTGGCGGTATCCCACAGCACCGCGGTGGCGCGCTGCGTGGCCAATGCCAACGCCACGATGGCCTGGCCGTCGCGACGCGCCTGCGCGATCACCTTGCGGCACACCTGCAGCGTTCTTTCGAGAATCGCATCGGCATCCTGCTCGACCACGCCGGGGCGCGGCGTATCGACCTGCAGGGCCAGGTATTCCTGGCCCGACACGTGGCCGTCGCCCGACACCAGGGCGGCGCGTGTCCCCGAGGTGCCGGCGTCGATGGCCAGGATCACGTTGTTCGACATGTTGTCTCCGTGCGTCATCTTGCGGTTTTCCCCAGCGCCGGATCGAGCGCGGGCAGGTTCTCGTCCCCCTTGAACTGCGGCGCGCCGGCTTCGTTGTCCGGATTGATGCCGCTGCGGGTGGGATCCCATTTGATGGCAAAGCAGATGATGCTGGCCGCCAGCGGGACGGCAGACAGGATCAGGAAGGTCTTCTCCAGGCCATAGCTTTCGCGGAACAGCGGGAACACCAGCAGGCCGACCGCCGCGCCGATCGAGCCGAGCGCGCCGATGACCCCGTTGGCGCCGGCCCGCAATTCACCGCGGAACGACAGCGACGACAGGCTCTTGCCGTTGGCGCCCGGACCGCCTGAATGGAACAGGATGAACAGCGACGGCACCGCCACCGCCAGCCACAACGGCATCTTGCCGTGGAAGGTGCCCAGGATCAGCAACATCAGGAAGACGGCCGCAAAGCCGAACGCCGAGGCGCGCCGCAAGCCCAGCTTGCGACCGATGTAGGGCGACATGAAGCCGCCGAAGATGCCGAAGATGTTGAACACCAGCGCGCCCACCGTGGCGTAGACGAAGTCCTTGCCGAACAGTGCCGCGCTGATGAGCGGCAGGTACCAGCCCACCGCGAAATACTGGATGGACTGGCCGATCTGTACCGTGGCCGCCAGTATCGTGCGCGGCAGGTACACGCCGCGGAAGATCAGCAGCACATTGGCCAGGCCGCGCCGCGCCTGGTTGACCACCGGCACGCGCTCATGCGGCGGCGCCGCCGTGAACGGCTGGCCGTAGATGCGGGTCATCGCCACGGCCGCCTCGTCGACGCGCTCCTTGCGCGCCAGCCAGATCGGGCTTTCGACCATGTAGCGCAGTTGCAGCACCAGGATGGCCAGCGCGAACACCGCGGTGGCCGCGACCGAATAGCGCCAGATCGCGTCGCCCACTTCCCATGAATGGAACAGCAGCGCCAGCAGCAGATTGGAGCAGACCGCCGTGTACCACATGCCCTGCCAGGTGTTCAGGCGGCTCTTGAGCCTGACGGGCGTGAATTCCGCCAGCACCGCCATCGCGATGGCGAAGTCGATGCCGTAGGCCGCGCCCACGAAGAAACGGCCCGCCAGGATGACGTCGAACGACGGCGCGAACACCACCAGCAGCGCGCCGATCAGCGCCAGCAGCTTGGCCGTGATGAGAGGCCGCATGCGGCCCCAGCGATCCGCCATCCAGCCGCCGATGGGATTGAAGGCGATGGCCACCCAGGACGCGAAGGACGTCATCAACGCGACCTGGCCCGCGCTCAGGCCAAGGTCGCGCGTCATGGGTCCCAGGCCCGCGCTGAGCGCGGAATTGGCGAATGCATCCAGGAACAATCCGCCCAGGGCGAGCCACCATATCAGGCCGGCCCGGCCGACGATGCCCGGACATGAATCGATATACGCGATGACATCGTCGATGCCACGCAGCTTGACGGGTAATGATTGCACGGCGGTCTCCTCTTGGAATTATTTCTGTAAGAGGTCGACGCAGCGTGCGCGCGATAAAAGACCATCTTACAGATGGTCTTTTATCTAGATCTGTGCGAGTGACTTTATGGACTATCCAGCATAGTGTCAACCGGGAAAACACCAAGCCGGGACTGGCGGTATGCTTGCGCTGCGCGCCGCTTCCAGCGCACCCGATCCGTTCACTTCCACCTTCGCGCCACCATGATCCGACACGCCCTCGCGCTTTCCCTGATGCTGTCTCCCGCCCTGGTCCTGGGCGCCTCCACACCGGACTACATGGGCCAGTACGACCGCTGCCTGCGCGATGCCGGCGTCACCAACAACGGCACCGTCGGCGCCTGCGCGGAAGGCGTCTCGGCGGCGGCCAAGCGTGAAATCAACACGCTCTACGCCCGGGTCCAGGCACGCCTGGCCACCGACTACCCGGACGACGCCGCCAAGCTGGAACAGACCCAGAAGGCCTGGCTGGCGTACCGCAACGGCCATTGCGCGCTGGCCGGGGCACATGTCGGGTCACCCATGTATGAGTATTGCCCGATGCTGCTGAACATCAACCGCGCCGACGAACTGCGGGAATTGGCAGGCGACTGAGCCCGCGGCGCAACGCGCCGGCGCTTGCCGTGCCACGGCCACGTTGGTAACTTTGCCGTGCCCGGCCTCGCGTTCCCAATTTTTCGCATAGGACAGCGCCCACCATGACCATCGTCGTATACGCCGCCAACGCCCGCGCCCTTTGGGAGACCATCCAGGCGGACATCGCCCCTATCGGCGCCCGCGCCACGACCAGCGGCAACAGTTGGCGCAAGGACGACAGCGGCCGAGCCGCCAAGATCTATCGCGCCACGCCCACCGGCCAGCATGACGAACGCGCCTATTTCGTCGGCACCGTGCGCACCGGCCAGCTGATGCTGCTGGACCTGCTGCCCGGCAGCGAGGCGCTGAGCTGGCCGCTGTTCGGCGCCTTGCACGGCCACCTGTCGGGGATGCTGCTGGCGACCTATCCCGATGCCATCCTGTCATTGAACCTGTTCCCCAACCGACCCACCGAAATCTAAAAAGGCACGCCGTTGCTGTTGTTATCCGTATGTGTGCTGGCCGCCTCCTCGCTGGGCGTGCTAACGTGGCGTATCGTGCGCCGGCCCGAAGGCAAGACGCGCGGCGACATTGCCCGCGCGGGCGCCGCTGGCGCCGCCCTGTTCGCCGCGCTGGGTCCCCCGGTGGGCACCCTGGTGTTCGCGCTGTTTCTGGCCACCGCCGCGATGAGCCTGGAATCGCTGTTCACGTCGGTCTTCCTGGTGCCCTGGTCGTACCTGTACGGCGGCGTGCCCGCGCTGCTGTGCGGCCTGGTGACGGGCGCCTGCCGGCCCGCCGTCGTGACATGGCGCTCGTATTGCTGGCCGGGGCTGCTGGGCGGTCTCTATGCCTTCGTTTTCCTGGCGGGCTTCGCCGTGCGCGAGAACACGCTGTCCGAACTGGGCTTTCCGCTGTTCCTGGGCGGCGTGCCCGGACTGATAAGCGGCGTGGTCTGCGCTCGGGTGTTCTACGGCAAGCCGCAAGCCACCGCCCCCGCGGCCGCTTGAGCGCCGGCCCCGCCTTCGACCTCTCCGAAGGCGCCGCATGCGGCGCGCCGCCGATGGCGGCATCAACGCCCGCCAGCCAGCGGGCGTTTTCACCTCCCGGCTCAACCGCCGAAAGCGCGGCGCAACCGTTCCATTTCGGCCCGATTCAAGCGCTTGGCCTCGTCTTCGGCATAGTCACGCTCGCCCGTCTCGTATTTGCCTTCATAGATGCAGCTGCTGCGGCTGACCCGGCATTCCAGGCTGACCCGTGACGAGTCGGAGCCGGAACCGGGGGCAGCGGGCGAAGACCAGGGATTGATGGACGAGGAGGAACAGCCGGACAGGAGCGCGACAAGCAACAACAGGCCGCCGCGGCTAAGCATTTGAATCGACAACATTTATCCTCGCTCGACAAGAAAAGCTTCAGGACTCTTTATAACAAGCAGGGGATCGGCGGTACAGGCGCTGGGTCCGGCGCGGGGGCCGGTGTGGGGCCGGTGTTGGGGCCGGTATGGGGCCCGGTATGGGGCTCCGGCCCTCAATACGGGGATTCAAGAGCGGTAGATGGCCAGCCAAATGAAAACCCCGGGACACAAGCATGTCTCGGGGTTTGGGGGACACTGCTGCCGGCGTATCGCCAGATCAGTGCCTGAATGGGGTTGGTGCGAAGGAGGGGACTCGAACCCCTACACAATCCAGTGTTCATGCGGCTTTGCGGCCTCATGTTGTCCGTAAGTTGTCATTCAGGCGGGAGGGTCATGAGCCCTTCCGCCTTTTTTCGTTTGGGACCCGAGCGCCGAACCTATACTGGACCTTCCCCCTGGTCAGGAGCGCGTCATGTGTGGTCGCATCGTCCAGAAGTCCGGGCCGCTCGATTACGTCGAGCGCATCTTTCCCAACCCGCGCCGCGTCTTCGATGACCCTGCCGGCCCGCTCTACAACATCCCGCCAGGCACAAGGCCGCTGACCATGCACCGCCTCGCCGGCGACTTCGAGCTGGAACGCCTACACTGGGGCTGGCGCCCGCACAATTCGAAGTACTTCATGCCAAGCGCGGCTGGACAAGATCCTCGCCGGCGCCTGGCCCTGGAAGATGCTCACCGCGCGCGGCCGCATCCTGGTGCCCGCGGATGGCTGGTATGAATGGAAGCCCCTCGCCGATGGGCCGAAGCCAGCCAAGCAGCCGTACTACATCCACGCCGCCGACGATGCGCCGCTATTCTTCGCGGGCTTGAGCAACTGGCGGCCGGACGCGGAGAAGGACGAGGCCCACGGCTTCGCCATCGTCACGAATGACGCCGCTGGCGGCATGATCGACGTTCACGACCGCCGGCCAGTAGCGCTGCCGCCCGACCTGGCCATCCACTGGATGGACCCGGAATTTCCCACCGCCCAGGCGCTTGCGCTGCTGGAGCATGGTCTACCGGAGACGGCCTTCACCTGGCACCCAGTGCGCCAGGAAGTCGGCAATTCCAAGTACGAGTTGCCCGACGCTATCCAACCAGTCGCCCCTATACCGAAGGATTAACCCATCTGATCGATATCACCCCTGGTCTTATAGCAATACTGCATATCACATGCCGCGCGATCCTCAACGCGCATGGGCGGCGCTGACAGTTGTGTCCAACAATGAAAATCATGGCGACTCTCGACTATATCGTCCATACTCGACACCTCTCACCCGCAAGCCTACAGAGGAGGATTCTTGATGAAAGACGCACCTCGACATATGGGATACCGGGCCGCAGCGCACGGACAGCTGCTTGAATCTTGCCCATTCTTACGGGCCGACAGGCTGCCGACTCGTACGGGGGAAAATCTGACCCACTGGCGCGAAAAGGTCGAAGCGTGGGAACAGGGTTGGCACGACTGTGTTAAGAACCGCCCTCCTCTTGTTCTTGATGACGCGGCTCCTAAGGCGTCCGAAAAGGACAGCCACCACTAGGGGCTCCAATTCGGCATATACCGTATTGCGCTACATCGGAGCCCGATGTAATTTCCCCATGCCTCCGGAGGGGGTGGAAACCTCCGCAGGACATCCACCCGGTCACGCGCCTTCTTCGCCGCGTAACGCGGGTGGGCCACGAACGCGCCTCCCCCGGCGGCTCAATCCGCTCCCGGTCCGCGCCCCGCTGGACCAGACCACCGATCCAGCGCCTGCAATCGGGCGGCCTCCGCCTGACGCAGCGTGCGGTAGAACATCGCACCGCTGGCCACCAGCGCCCCCAGATCCCTCTCGTTCAGCTTAGGAGCAAGCCGCTCCAGGTGGCGCGCGTAAATCACCAGCACGCTGTCCCAGTCATCAAGGTTCGGCGCTGGCGCAGGCGTCGAAATCATCATGGCCAACAACTCTTCACTGTCCATAGGCGGGCCTCTATCACAACCGGACCAGCATCTCACAGCGCGCCAGAGAAGCCGGAAAGAATCGGTAAGAGCGGCCTACCGGCGTCACAAGCCTTGCGAATCGTTGCATGAAAACGGGGCCGAATTGCATCCGGGCCTGGGGAAATTATACTGTTTATCCATACAGTATTTTCGAGCAAGCCGTGCAATTCCAGTGCAGCGTCCTCCGGACGCACCACCTTGGCGAACGTCGCCGCGATAACGATCCAGGCCAGCCCGTCGTGGGCACGGTCCGGATGTACTCCATGCTTCACAAGGGGCTGAATCGCCATGTTCCCCGAATGACCATGGACGCGCTGGCAAAGTTCGGTGCCACTGTGCCCAGCGCCATCCCCGATCTACTGGAACCTCAACTCCTTACCTTCGCCTCAGACCGGGGCATGATGGTCTGTGGCTTCGAAGAAATCGCCGGCGTGCGCTACTACCAGGGATGGTGGATGCAATGGATCGCCGAGCGAGCCTAACGTCACCACGAAGCCAATGACCGTGATAGATTTATCACGCTCGCGACGCCCATGCCGGCCGCCGCAGAGCATTCGCCCCAGCCCCCTCACGGGTTGGGGCGTTTTCGTTTGGAGCCAAGCTTCCCGAAGCCATCCGCGCCACCTGCACCACCTGCACAAAATAATCACTCCTGCACAACCTGCAATTTTCATTTGCTCCTGCACCACCTGCATGTTACAGTGCCTCCTGCTAATTCCTTCGGAGGCTCCCATGAGCGGCTTGGACACCGTCCTGACAAATCATCAACGCGTAGTGAGGGAAGGCTACAGGAAAGAAGTTGGACAAGGTTTCAAGAGCTACGCCATCTCAAATCTGCGAGGGGGAGTCGGCAAATCTTCTATCGCCTTTAATTTGGCCTATGAAATGTCGCGACAAGAGGCCGTGCTATTTTCCGACTTGTGCCCTCAATGCAATTTCACCGAAACATTGTTGGGCGATTTCCGGCCTAAGGTGAACATCTATGACGCGATGAAGCCCATGATTCTGGGCTCGGCGTTCGGCGACATTCCCACTGACCTCACGTACAACGTCGCGCGATATTGCGACGACTTCAAGGGAGGCAAAGGCGCATATGTCATCGGAGGCAGCCCCGAACTATTCGCGTTCCCGTCCCTGTTGTATCAGCAGCTCAACACCGCCTATTCGCAAAAGAATACGGTAGCCGTAGAACGGTTGCTGCACGGTCTTCGGAACGTGCTCGAAAAAGAATCTGCGGAAGCCCGCTGCAGCAAGATATTGCTGGACACCAGCCCGTTCTATGCTGGCGGGACTCACTTGGCTTGGTGTGCAGTGGATGCTTTGATCGTTCCCGTCCGCGTGGACGAGCATTCTCTTGAATCGCTCGAGTTGCTCTTAAAAATGCTCTCGGACCCCGCACGTGATTATCAAATGTGGAACGAGCGGGCGGGGGGGCTGTCCGTTCCCAAGATCGCTGCGGTGGTCATGACCATGGTTGGTTCGAAGAGCCAAGTTGAGGCAACGCCGGATAGTGCGTCCAGGATGTACATCGAACGAGCTATAGGAATCGCCGAGAAGTATTCGCCGCTGTTTGGCCATTCAGATCCTAGTGACGCGTTCGTTATCACCGACGATTTCCACTCTGCGGGCCGAATTTCTGGCGCGCGGCGCATACCTATTACCGAACTCCGGGTAAAGACCTTTCACACTGTCGAAGGCCGCAGGTTGCAGGTCAACGCGTCCGCCACCCGCTACCAGAAGCAGCTCAGATACTTGGCCTCGATGATCTAGATACCCTTGAAAATATAAGGGGCTTCAGCGCGCCAACGCCGAAGCCCCTCAAAGAATGCGAAGCCCAAAGGTCCCATGGACGACGCACCTTGACTGCAAGGTAGAAGTTGCATCGTAGTCGGTCGCCAAACCGACTGTCAAATGTCAAGGCGAAAGTTGGGACGGCGTCTAGGAGCATCTACATGCAGCCGAACGACACCGAAGAAGTCATCTATCGGATGACTATTACCGTAAAGGGACGGGTCATCCGTCGCCCTGACGGCCGTCCGTTCCGGATTGTGTTGCGCAAGAAAAAAGCCAACTAACGAGCCGGTATCAAAAAGCCCCTGGCCGCAGGCCGGGGGCTTCTTGTATTTCGCGCGAGTTCATCGTCCCGTCGTACATAGGCGATCCCAGGTCTCATTCCTCTCCAGCACTTGGCGCCGCACATCCGCCGGCGTTCGATCCACCTCGGCGGGCGAGTCGAAGTAGATCGGCCGCGCATGGTCGCAATACTCAACGCCCACCCTGGCCGGGGCGGCGCACCCAGTCAGACTTGAGGCGATCAGAAACAGCATCATCGTCCATACGGGCGACTTCATCCTCCACATTGCGCACCTCCTGGCGAGCCTTCGCCGCCTGTTCGTTGATTCGGTCGTTGCGCTCTTGGCGCTCATCTGCCCGGCCGGCGCGGCGCCCGCGCAGGTAGACCAGCACCACCGCGGCTACAGCCGCCAGCGCGGCGACCACATAGCCCCGTATCCGTTGCATGAATGCGGGCATGGTCAGACCTCCACTACGGCCATGGCCTGGGCATACAGCGCCGGCCAGGTCTGCGGGTGCGGCTTGCCGGGCCGCCAGGTGCGCAGATAGAGCGACCATCCGGCGTCAACGTCGCCAACAGCCGGCAGCGCCCTGGGATCGGTCCACAGCAGCAACCGCGCAACGCCGGCGGCCAGCACGTCGTCATACTCCAGCGCCGCGTAGATCGCGTCCGGGTCACAGGCAACGCTGCGGGCCTTGCACAGCGCCGCCAGGCGGTCCTTGCTGGCCTGGTGCAGGAACACGCCCCACACACCGCCGCGGCTGGCCCGCGTGCCCTTCTCGAACTGCCAGAAGCCCCGCGCCGGCCCGCCGATCTGCTGGCGGTGCGTGAATCGACTTTCCTGCAGGCCGATTGCCAGCAGCATGACGCGCACCGCCTGCGTGTCCATGCCGGCCGGCAGCAGCGCCAGCGCAGGGCTGATGCCCGTATCGATGATCTTCTTCAGATCCATGGTTCAACTCTCCCCGCCCGACCGCAGGCCCAACAGCTTGGCCCGAGCCTCGGCAAACCATTCCAAAAGCCCCTTCTGCCGCATGCTCGCCATCCAGCGCATGTAGGCCCCCAGCACCCACCAGGCGGGCAACCCCGCGAGCAACATGCACGGCCCCAGCACGTAGAACAACGCAAGTAGCTTTTCTTCGCCGCCCCCGCTGCGCGCCGCCACCCAGTGGGCCGTTTCCATCAACGACGGCCGCCACGACAAGACGGCAATAGCCAAGATCGGACCGAACACGAACGAACACGACACAGTGCATACGGTGCGCTTGATGAACTCCTGCGGCGACCGCGGCGGCATGATGACCATGCCGAGGATGGCCGCGAGCGCCGCCGGCAACCCAAAAGCCAAGGCGATTTTCACGGCCGCCCAACCGCCCAATCCAGTGGAACCCGGTTCCATTCGCATACTCCCTTGATGGGTTCGCATCGCTGCCCTCCCGTTGTGTGGACGAAAAAAAAACCCGCCGAAGCGGGCCAGATGCCTGTGGGGTCAGCTAGAGCCAACCCGTTACGTCGATAACAGAAACGGGGCAAGCCCCGCCATAGCTCAAGAACGTATTGCTGTAGATGGGCGCCCAACCAAGATAACGAGTCCCATACTCGGGAAAGTTTGCATATAGGCCGTTCGCTGTGGCTGTGATCCGTTCATCGCACGTCAGTGTTTCCCAACCGCCGCCCATCGCAGGCAGGCAGTTGTAGCCCTGACGCGTGTATGAAAGGTTGTAGGCGTACTTCGATGAAGGCAGGCCCGAGAAGGTCCAGCCGTCCTGATATGCCGTCCGGTAGGCGTCGAAGTAGGTCGGAATGTCGAAAGTCTGGACCACATTCATCGGGCGGGCGGTGCTCATGAAAATGTGCCGTCCGCTCTGGTCCCATATGTCGATGGGGCCACCCGTCACCCAAGGCCGGTCGAACACGTAGTACTCGCATTGGCCGCGGAACCGGAAGAGGTATGTGCCCCCGCCCATATCCATAGAATCGACGCCCCCGAATCCCGAAACGGGCCGGAAGAATAGAACCGGATCGAGGCAACCCAGCGTAACGTTGTTGTAGCGATCCGGCCCTGTCACCCCCGAGTACCGCAAGAACATATTCACGTTCCGGCTGTCCACAATCAGGTCGCCGGCCTCGTTGTAGAGGACGACTGCTGCATCTGCCATCACTTGACCCCGTAAATGACTTTGACGCCAACGCGCGGGCTGGGATGCCCGGGTATGAAGCGCCAGGAAATTGACCCTCCGACGCGCGCGATCATCGCGTTATTTCTCGCAAAGCCGTAGTCGCCTATGGCTTGCACAGCGATCCAACCATCTGGACCGTTGATCGCATCGATGTACGTACTGCCGTCGCTGGTCCCCGTTGAGAATGAGCCTAGTTGGCGGGCGACCCTGGTATTGAAATTGAACAGCTCCCGGCCGTACATGTCCCAAATTTGAAGCGGCACCGCCATATCACCCCCCACCAAATCGGGCGCCCAAGACCCCATTCGGGTAGTAGTAGCGCATACCGTTGTTGTTAATCTCGGTACGCGATCCGTCCGACACCGTGCCGTTGAAAGACATGACACCAGAACGCATATTGAGGGAGAAAACCGGCAGCCCTTGCGGATTAACCGCATCAGACCGAAGCACGTCCGCGATCTGCGCAGAGCCAATGGAAGCCCGCCCAATGAATGCTTGATTTATGAACACCTGCCCGCCCTGCACCACAAACGGCGTTTTGAGCGAACCCGAGGACTCATCCAGCACTGCGACCCGCTGCGCCGACAGCAATACCTGAGAAGTGACAACCCCTTTGTCATTCTCTACACCCACGCCAATACCGGCCATGTAGGGTTTACCGTCAACGGTCATCTGGGTCTTGACGGTCCACATGGCAGCCAGCGCCGAGGTCAATGCCGCCACTTCCACCGCGGCCTCGCCCGCGCTATCGATCTTCTCGCGCAAGGCCTGGTAAAGATGAGTCTCCTTGATCTGGCCGGCGATGTAGTCAAGAATGAGGTCTGCGTCTGCACTGGCCTTTCCATGAACACCGGCTCCAGATGGATATATCTCGCCAGCGACCCCATTCTTGTCAACCAGCCGTGCCCAAAACCAAAACTCCACGCCAGCAGCCAACCCCATCAACGTATGAGTATTCTGCGGGTAGGCAAAATCACCGAGCCGCGTCGCATCATCGAAACTCGGCGTTCTGCTATAGAAAAGCTCGGTGCGGCCGATAATAGAAGGCCCCGCGGGCAACCCCCAATCCAGGCGTACCCCGAAAGCCAAGCTAGTCGTCGCCATGGAGGTCACCCTAGGCGGTGGTCCAAGGATGCCGTCAAGCTGCGTCAGCGTAGAAGTGCTCCAAATCGAAGCCACGTCCAGCGCATTCAGCGCTCGCACGCGAAACGTGTAGCCGCCTGCGTAGATGTTCGGCACCTCCACCCGCGTGTAGCCCGTGCGCGGCAGGTTGATCCAGTCCGAGTTGTCCCGGCGCCACTGCACCTCATAGGCCACAGCACTATCGGCCGCCTTCCATTCGAAAACGGCGGTGTGATTCGCAATGCCCTGGCTGACGATGTAGTACGCGCTGATCTTCGGTTCCGTGGGCGGCGACTGCACGCCAGGCGGCACGACCGAAATCGGCGGGCGGTCCAGGCGCGTGCCGAAATCCACGTTGTTGAATTTGCCCGGCTCGTGCTGGATCGCTGAGATTTCGGCTTGCAACCCGTCTTTGCGCTCGATGCGCAACACGCGGAACGTCTGCGCGGACAGCGCCTCCGATTCCAGCGTCCACACACATTCGGCCTCGGGAACTTCCGAAAAGGGCGTCTTGACGTCGATGTGCATGGCCGTGCCAGGCAGGCCGATCAAGTCCCAGGTCAGCGCGGTCGAGTCGTAGCTGTAAACCCCGCTGTCCAGCGTCAGCGGCTCGCCCATCGCTGACGACACCACCCGCGTTTCAGACTTGCCGCTGGGCAGGTTCACGGTCAGCCGATCACCTGGCCGGATGCCCAGTTCAGCGTCAACCACAATTCGGCTTGCGGTAGCCTCGCGGATACGGCCGCCGATGCGCCGGCCGGCCAGATGCTGGTCCGCAACGCGGATGATGCTGCCGGGGCGGATCTGGCAATGATCCAGGCCCACGGTGAAGGTAACACCGCGGGTTTCCAGCTGGGAAGTGAGCAAAAGCCACTTTCCTACCCGGTTCGCCTGGCCGCGCGACGTGCAGCCAAACGCTGTCACCTCCAACTGCTTGATGCCGTAGCGTGCGATGCCTTCGCGGTTCTCGACGTACTCAACCTTTTGGCGCCCCATGTCGGAAAGGTCGTTCCAGGACACCAGCGCCACCGTATACCGGGTATTGAGCGCCGAGCCGGTGTAGTTGAACTTACCGCCGATGACGTTGGCCGACGAGAAGGTGTAGACCGGATCGCCGGGCATGTCTGCGACAGCGAACACCGACGAATTCGCCCAATAGGCCATACCGCGAAACACCGACGCCATGTCTTGCAGGACACGCGTAGCGTCTGCGGTGGTCTGCAAAAAGACATTGCACGCGAACCGCGGTTCCTTGCCGCCGAAGCCGTCGTCCACAAGCTCGTCGCAATATCGCCCGATCTGGTACAGGCCCCACTTGTCCAGCCATCCCGCCGGAACGCGCTCGCCCAGGCCGTAGCGGTCGTTGCTGACCAGGTCGAAGAACACCCAGGCCGGGTTATCCGTCCATGCAAGCTTGAACGTGCCATCCCAGACGCCGGTATAGGTGCGCGTCTCCGGGTCGTAGTTGGACGGCACGCGGATAATGCGGCCCTTCAAGTCATAGGCCCGCGTGGGCACGCTCTGAAACTGCGAAGCGTCCACCTTGATCCCGACCACCGCCGACATGGGGTAGCGCAGTTTGGCGTCGATGACCTCGGTCACGGCGTCCACCACCGTGCGGTCCGAAATCGTGCTGCTGTTGGCATTGGTGGTCAGACGCCGTACGCGGACATTCCAACCCTGCAAGGCGCCCGCCGGCAACTCGATCCGATGGGACCGCGCATAGCGCTGCGTGGTCTTGCCATCAAAGGCGCTGGCCAGCACCTGCTGGTAGGCCGCACCGTCTCGGCTCACGTCGATTGCGTACTCGACACGGTAGCCGTTGATATCGCCGTTTTTGGTGTCGGCGCGGCTCAGTCCCTCCACCGCCAGCGTGACCCGCACGGCGGACAGCTGACGATTCGTGAACAGCCTCACCCAGGGCTGCGTGGCCTTGAGTTCGACGCCAATGCCAATGGTATTTTCCGAGGCAGGAAATCCCGGCAGTGGATCCTGCCACTGCGTGCCCGTGCGGAAGTCCACCGAGACGCCAGAGAAGTTCAACGAGCCGTCTTCATTGGCTACCGGCGTCCCGTTTAGGTACACATCACGCAGCGCACCACCCAGGCCGTGCGTAGGGCCGTAGATCTCGCCTTCGCTCAACAGGTCGATGACGCGCGCGTAAGCGATACTGTGCAGGCTGTCCGGTGCCTCGGTAGGCCCGCGCCCACCGCCGCCGCCCTTGCCACCCTTGTGACCCACGATGACGCGATCCTTGCGCCCATAAAAAAAGGCGCCCTTGGGCGCCTGTCGCTTCATGCGGACTCGCTGTTTCATGCCTGGTCTTCCGAAAATATGCCGGCTGAAATCGTGGCACTGCCGACGATCATTCGCCCGTACAGAATCGGCACCGGGTTTCCCTGGGCCGTGGTATTGACTGGGCCGTTGAAGTTGTAGGAGGCGCCGTTTTCCGGCCGGTCCCTGGTGCTCAGGGCCCGCTGTTGCGGGGAGAGCATTTGAACCACCCCACCGAAGGCCAGGGAAGCGCCAATCATCGCCGTCGCGCCCACCCAGCCTTTCGCGGCGAACGCGGCCGCCAGCGTGCCTCCCGATGAAGCGAACGTAGCCACCGCGATCAACGCAACACCCAGGACCGTTTGAAAGAGTCCACCTCGTTTCGCGCCCCTGGGAACCGGCGCAATCCGGATATCATCGTCCCCGACCGGGTGCGATAACTCGCCCTCGGGGATATTCCTGCGGCCGACGAAGCAGGCGTAAGAAACGCCGCTCCCGGCGCTGGCTGCCATAGCGGCCTCGAAGCCCGGAACTAGCACGCAAAGGGCGCGTACGGCCTCGGCAGTGTTGTTGACTGCCAACCTATGCACCCGACCGAATTCGGCCCCCAGGCGGCCATACAGCCGCACAGTACGCATTGTCTCGATCATGCTTCACCCTTGATATCGCAGCACCAGGCGCGTGGCCTCGCGCCAATAGCCGCCATACACCACACGTTCGGACTGGCGCCCGTAGAGGTGGTGCAGCATCGCGTCAGGAACCGAGAACAGGCCCGGCGCTTCCTTCAGCCCCTCGGCGCCTAGGAACACGCCGGCGTGGTTGGCGCGGTTGGATCGCACCTGCATCAGGATCACGTCGCCTGGCGCCATGTCCTCGCCGGCTTGTAGCGGCCGGAATCCCGCCTCGGCGTAGTGATCCATGTACAGGTCGCCTTCGCGGCCCGGCTCCCACCATCCGTCTTCGCGCTGGAAGTCCAGCAATTCGATTCCGCGCTCGCGCCTGTACCAGTCCCGCACCAGGCTGTAGCAGTCCAGCACGCCATGCGCGAACTGGCGACCCAGCAGAGGGGCCTCGAAGCCTACCGGCGTAAAGCCTCGGACTTCGCCCGCCACCACGGCGCCCGCATCGTCCTTGGACACCTCCACGATGTACCAGGGCAAACCCGTTGCCTCGCAGGCAACGCGATCCGCCTCGCTCGGTGCCGGCGTGTCGTCCGGATGCGAATGCACGATTGCCACCACGCGGCCGGCGTCCTCGGCGGCGGCGTAGTCGTCAGGCGCCAGCACGAAATGGTCGCCAGCCGCGGCAGCATTGCGGCACGGCACATAGGATTCGCGCCGCGCCGCCATCACCACCAGCCCGCAGCACTCGCGCGGGTACTCGGCCACCGCGTGAGCGCGGATGGCCTCCATCGTCTTTTTTCGCATGTCTACCCCCGGATCTGGTCCGAAGAGGGGAAGCCCCCGAAGTTGATGACCTCGTATTCCCCGAATCGCTTCTTGCAGTCCGACATGAGGCCCGAGCAGCGGTCGCGCGCGGGATCCGTAACCGGGTTGCCGGCCAGGTCGAACATGCGGCTGCCGGTGTAGCCGCAATACGGGCCGCGATAGCCGCCTTTGCGCAACCAGCCACACACGGTGGCGATAATCTGGCGGCCAGGAAGTTGCTGGCCGTCGAAGTCCAACGCGCTGGAAAGCGTGAACTCCACCAGTTCCGCAGTCTCGACGGTCTTCTGCTGGACGATCCACACTTCCGCCGGCAGTTCCTCGGCCGGGTTTGCGGTGGGGTTTCCCTCCGGGAAATTCGCCGCATCCAGATAACGGCCCAACGTCCGACGCACGCGGACCCAGGCCCCCACCAGGTCGTTCAGGTGAATGCACAGTGACGAGATCACGCCCACCACCGGTTCGCCATCGGCGCCGGTGCCGATGTTCCCTACCGTGAGCGTGGGCGTGGGCTGCTGGCCTTCCCCCACCTGTTCAAAGCCGGCCGCCGTGATTGCCCACGGCTCGTATCGATTGCCCTGCCACAGGATCGGGCCGATCTGGGTATAGCCATGGAAACGCTGAAGGGCGCCGCCGATGGGCGTGGCGTCCAGCTCGTAAAGCTCGACAAGTTCGCCCACCTCCAGCTTCTGCACATCTGCATAGATTCTCATCGCCTACCCCCAAGCTATCGCAGCCAGTTCGTTAATCGCGTTCGGCCCAGGCTGCACCGCATTGACCGCGTCACGCAGACGCTGGCGCTTGCCCACAAGTACCTGGCTGGCCGCCAAGAACTGGCGGACCTGCTCCAATGTCTTAGTGCGCATGTCAATTGCGCTTATGCCGCGCTCGATCGCCAGTCCGTCCAGATACGGAGTGGCCGCCTGGCTGTTGGCGTCCCACGCGAGCACTTCCTGAAGCTGAACCGTCCAGGTCAAACGTTCGGTCTCTGGATAGCCCACAGTCAGCGCTGATGCCGCAGATTCAAATGCGTCGTTGATCTCCGAGTGCTTGCGGCGGCGGACCTCTTCAATTGAGGGAAGATCCTCAGACGGCAATAACGGAGGCCAGGCAACACCTTGTTGATCCATTCGCCAACCCACGGCCGCCTCAGCAGGGTTCGGCGGCACCACTCTGAACCCTGGCCCCGGGTCGAATGAATCGCCCGCCAAGATGACGTTCACGACCATTCCTTCTTCGTCGACAAGTAAACGCATGGCTGCCCTCAATATTCAATGATGACGACGCCACCGCGACCCGCTGCGCCGCCGACACCAAACGCGCCGTCTCCGCCGCCGCCCGCCCCACCTCCGCCGGCGCCGTAGGCACCCGCGTCGGGGGAAGAACCGGCCAGGCCGCTGGATCCGGATGCCGCTTCGCCACCCGTGCCGCCAGCCCCGAAAAAACTTGCTCCGCCGTTGCCTCCGCTTCCTCCTCGAAGCGAAGTGCGATCAGCACCGGCAATTCCCCCGCCGCTCGCGCCCGCACCGCCATAGCCTCCTGCGATCGCGTTCTTCCCAGCGGCGCCCGCGGCGGGATTCAGGCCCGCAAAGCTACTTGCTCCGCCGGCAGTTGCAGTCCCCCCGCCAGCTCCTACGACGATCGCCATGGCGACGCCCGGGGTAGTTGCCACCCACCCCTGGGACATCCGGCCGGCGCCTCCACCACCGCCGCCCCCGCCGTAGCCGGTGGTCAGTACCGAGCCACCACCGCCGCCACCGCCGGACTGAACCGTAGCGAAGACAGATTTTGTCCAGGCGTCCGGTGTCCAGTTTTCGCTTAGCGTCACCACACGTCGTATGCCGCGAGAGCCGGGAATGCTGTAGTACTTGTTGTCAGTGCCATCCCATCGGCATGGGCCGATCCCATTGACCCAGATATCGCCGATGTTGGTTGCAGGAACAGCCCCCTGATCGAACGTCCTGCGCTGAGCGTAGACTGCCCATGACATGACGTAGGCGCTTACCGCCCTTGGGACCGTACTGGACCCGGCCTCGGCCTCCGCCCGCGACATGGCTGGCAACTGTGCAACCGGGATCAGCTGGTTGGAATCGAGCGTAGCCACCCCACCGGCAGCCCCCTTTTGTGTCAAGGGAATTGAGTCCTCGGCCGCGGGCAGATTCACCGCAGGCACCTTGCCGTTGGCGTCAAGCGGAGCAACGCCCAGCGCCGCCCCCTTCTCTTCGGCGAGCAAGTAGTCTTCCAGGTGCGCTGCCGGCACCTTGCCCGTTGCGTCGAGCGGCGCCACGCCGCCGGCCATGCCCTTCTGGGCGGCGGGGATCGCGGAGTCGGCCGTGGCCTTGGCCTCGGTGGCGGTCTGTGCCGTGCTGGCCAAGGTCAACTCCACCGCATCGACGCCGGTCTGCACCTTCGTGAAGTTGGCGTTGACCTTGGCCATGCCGTTGCGCAGCGGGTCGCCCGTCTTGTCATTGGCTACCTGGCCAATGGGGATTTGTTCAAGTTCTTGCATAGTCTCTACGGCGCATGCCGCTGTGTGAATGTCACCGAGATCGTGTACCAACCGCCTCCCATCGCCACCAACTGGTAGTCGCCGGCGCGGTACGACGTTTGGGTTCCAAGCGGGGCCGTCCACAGGAAGGCCTGCGAGGCGCCGTGGCGATCGAGAAAATCCTTGATCGGCCGGATTTCTGACTCGCTGCCAAAGAACGACAGCGGCCAGGACTCGGTACGATTGTTTATTCCATCCCCGACGACCTGTTCATAGCCGTCGCCAAACTGGGCCCGGAGAATCCTGAACTTCACTTCCGCCTGCGGATTTCGCCGGGGGCTCCACTGAAAGACCTCCAAATTGCTCATTGCCCCTTCCTTCCATAGCGCTCGTTCCAAGACGCCCCGCCTGGGCGATAGGACTTCGCGATAAGAACCTGGCACCGCGAATCAACGAATTCCCCCAGCTCACGCCCGAATTGCTCCAGACCCTGGGGGGCTTCCGTCCTGCTAGTTCCATCCTGTTGCATATAGATGTTGACCTGCACGGGAGCCGCCGCTTGCGACGGCTGCGCCATGCCGATGGCCTGCACCCCGAGACGTCCGTCCGGACCTCGCCGCAAGGGCATGATGGCTTCAGGACCCGCCTCAGCGAACACCCCGGCTCCTTTCGCGAACTGGAACACCTGGGGCGTATGGAAGACGCCATTCGAGAAGGCCGAGAGACTCGGCGATTCGTAGACATTGCCTTTGGCATTGGCAGTCCAGCCATTCGACGCGATCAGCGAGCCGATTCCGTCACCACCCGACGCCTGGACTTGACTTGCTGCCGCTTCAGTTCCGGCTGCAGCTCCAGATGCAGCGCCGAACAAGGAGCCGACGACGCTGGTGAAAATCCCCATCGTCGCCTGACGCGCCGCGATGCGCGCCAGGTCAGAAAGGACGCTCTTCGCAAAATCCGCGAAATTCGCCTTACCGCTGACCACGAAGGAGGCCACCGCGTCCGACATGCCCTGAAACAGGCTGGAAAACACCTGCTGCGATTGCGCCATGACGTTGGCAGACGCGTCAGCCCAGTCGTTCAGCGCACGAATGGCCCCGTTCTTCCAATCGCCTTGAAGCGCTACCCGTTCCTCCATGTAGCCGCGCTCGCGCTCGATCTGTGCCTGCATTGCGGCATCGATCTGAGCAATGCCCTGCAGATATTGATCAGACTCCAGCGCACCGCCGCCGCCCTCGCGCAGCATCTTGTCGGTGAAGCCGTCGCGGATCCGCCGAAACCTGTCTTGCGCTTGGTTGATAGCATCCACCAGCGCCCGATCGTTGCTGCCCAGGGTCAGCGCGTTGTTCTGCCGGCTTTCCTGGAGAGCGCGGGTTTCGCTGTAATTGGCGATATCGAGCTGCGTAGCGCGTAGGGCGCCCCGGATCTTGGCCTGGTACTTCTCGATATCGGTCGCCTCTTGCTGCTGCGACCTCGCGATCTGGGCCTCGAGTTCCTGCACCCGGCCGGTGTAGCGCTCGCGTTCCGCGATCTGCTTCTTGCCGCCGGCGATATCCGCTTGTTTGCGGGCGATGTCCAGCTCGTCGCTGAGGGCTGCCCGTTGGGCCGCCGCCCGCCGCCGAATGAATGCCTCTTCGGACAACAGGCCGGCCGCCCTTTGGCCTTCCAGCGCGGCCGTTTCAGCGCGCAAGGCCTCCTCACGCATGCGCGCCTGGGCTTGCATCGCTGCCAGCTGGCCAGACAGTGAATTCTGCCCGGCGCTGACGGCGTCCTTGTCCTGGAACTTCTTGCGGGTCTCTGCTTCGCGTTCCCGGATGGCCTTGGACGATATCCGGTCATCCTCGGGATTGACGGCACGAATGGCCGCCTCCAGGCGCGCGTTTTTCTCCAGCGCCTCGGTCAGCTGCCGAACCTTGTTGGTTTGCTTGTCGTAAGCATCCAGGCTCTTGGCCGCCTCGATAGCCGCCGCGTTCGCCGCGGCATTGAGCCCCTTGACCTGCGCAACGGCATCCGCCAGGCCCTTCTGATCCAGCGCGTCGCCCAGGGCACCCTCGGCATTCCTCACGCGCGCACGGCCAGCCTCGTTCAATCCGGCCGGCCCTGCATCACGCTGGCGCATCAGCGCAATGTTCTCGCGCAGCGTGGCGATACGCGCTTCCAGCGGGTCCTGCTCCTGCCCCACCCGCTTCATTGACTCCCAGGCGCCGTCGACGGCGCCCTTCACGTCACGCCACGCACGCTCGAGCACGCCCAGTTTTTCCGGCGCTTCAGTGCCCAGATAGTCGTGCAGGGCCCGCGAGGTCTCCTGCATAGCACCTTCGCGGTTGCCTGTCTCCTCCAGCGTGCGGATGTAGTCCCATTGAGCCAGGCTCATGAAGTTGAGCGAGCGGTTATGCTCCTCTGCCCACTTCGTCACCCCTTCGGGCATCTTGGCGAAATCCTTGGAGATTTCGTCCATGGCCTGGCCCGATGCCTTTTGGAAGGCAACCATCGAGCTTGACATCAGCTGGATGGTATCGGCCGAAATCTGGCCCGTCGCGACCAGCGCCTCGACTGCCTGCTGCGCCTTGCTGCGGCTTCCATTCTCACCAGCTGCGGCGGCGGCCATACTGCGGATCTTCTCCGCCGTCACCCCCGCATAGTTACCCGTCAGCTGAATAGTCCGATTCAGGCGCGAGGCGTCCTCGCTTCCCTGATAGGCGGCAATACCGAAGGCCACAGCCGCGCCAGCGGCCAGGGTATAGGGGTTGATCAGCCCAAGAAGCGTGCTTCCCAGCGCCTTCGCGGCCGGCACAACGCCGCCGAACATGTCCTTTAACTGGCCGCCCTGCTGCAGCAGCACGGTCATGGGCTGTTGCCCACCCTGCAAGGACACCACGATGTCGGTCAGCTGCGCCGGTACACCCCGCATGGCAGCTGCGGTCTGTGCGGCGCTGTTGCCGTACCTATCCAGCGCGCGGCCGGACGAGCCCAACGCAACTTCCTGTTCGCGCAGCTTGGCAATCAAGGGAGCAGCACGGGCTGAAACACCAAGCTCGGCCGCCTGCAGCTCGAGCAATTCGGACCTCGTCTTGCCGATCGCCTGCACCTGGCGCTCAAGGCCCTGGACGAATCGCTCAGACGTCTGTACGAATGCCTGGCTACCCGCCGCCGACGCGTTGACCGCTTGGGCCATCTGCCCCGCAGATGCGCCCATGCGCGCCGATGCCGCGCTCGCTCGGCCCAAATTGGCCTCGGCCGTGGCGGCAAATTCCGCCGTCGCGGCACCGGACGCCGAGAATCCGCGTAGAAGGTCAGCTTCGTTCGCGGTCAGCGTGACGCCTAGAACCTTGTCATTCATTGAATTCTGCCGCTGAAAGTTCAAATTGCCGGCCTACGCCTGCCCCAAAAAGACCTCCAAGGCGGCGCGCTCCATCGCGCGGATATCCAAAAACGCCTCCCTCAGGTCCGCCCCCGGAGGCATTAGGACCTCCAGCGTTGCGCGAATCTCGGTCGCCGAAATGCCAGTACGCAGTGGAGGCCCCATTGCGGGGGCCACCCAAGTCCAGCATGTTTCAAGCTCCAGAAATGCCCTGACCGTCTCCCAGTTCTCCTCGAACACCTCGAAGGGCTCGTCGGCCGCCCTGGCTCCTGCCGCGTCCAGAACGTCCGCAGGCGCACCGGCCAAGGTCAAGGCCGCCAGCACTGCATCATCGGGGTCGAATGCGGTCTCCGCGCGCCGACCGCCCGTTGCCCAGTACCGTGCGGCCTCTAGGAGTTTTTTTCCCGCACCTGCTGATGGGCACGCCAGAAACCTTGGAACAACGGCGCGACCAGTTCAGGCCAATCCTTGAGGACTTGGTCCAGCGCCTTGGCCGAGAACGGCACGGCGTCGCCCTGGCCGTCGCGCACCCCCAGCCACCCGGTCATCCGGTCCTTGATGAACTCAACGTCCGAGGCGTATTCCCACTTCTCAGCCGCCTTCTGCCCCTTGCCAACGGGCAGCAACGGCTGACCGAGACGCTCGCGGTAGGCATTGGTCATCGCGTCATGCAACGCGTTGATCTGGTCCAGGGGGCTGCGCTTGTATTGCGCAATGAAGTCGATTTCGACGGGAGCGCCGTTTTCACCGTGGACGGCGACCTTGATATCGCACGCCGCGAGAGCGCGCTTGCTGACAACAAATGGCATGTAATGCTCCAAAATGCGAAAACGCCCGGCAGGCCCGGGCGCAGGTGATAGAAACTGACCGCTCGCCGCAGCTTTTCAGCGAACGATGATTTCCAGTTCGTCGTTGCCCTCCGGGCCCGGGTTTACATTCATGTCCAGGCCGAGCATTGCCACGTTGCCCTGGTCCGAATATGCCGGATTGGTCAGCTGCGCGGTAGGCGCCTTGATCTCGACGATGTTGCCCGCTGCTGTTCCATGTTGAATCGCCAGCGCCTTACCTTCGCCGGACAGCACGATCGCGGGCCAATCCAGCTGGGCGATGCGCGGCAGCTCGAGGGAAATCTTGCCGGTCGGCTGGCGGTCGGTGATCTCGGCCCCTTCGCAGCCGATCAGCGAACGCCAGACCAGCTGGTTGGCGATGTCGAAGGTCAGCGACTGCAAGCAACCGGAATAGCTGCCTAGCGACCAGGCCGGCGTGTTGGCCTTGTTGACGCCCTTCGGGATCTGGAAGGCGCTGTAGTCCACGTCGGTCGGGTTGGCGCCGTCGGTGATGGGCAGATAGACGCCCATGAAACGAAAGCGCATGAACGGGATGCCCTTGGCAGTCAGGTCGAAGGACACCGTGCCGCGCGCATCCAGGATCTTGTGGAAGACGCCGTCCAGGTAGTAGTGCAGCGCGATGCGCTCGAAATTTTCGGACACCGGCAGGTAGCGCACGTCCGTTCCGGTCGTGACCGTCTCGGCGAAGCCACAAGCGCGCAGCAGCGGCCCCCAGGCCGGCGCCTTACCAGCCGTGCCCGACCCGGCCAGCTCGACCTCGCCTTCAATCTGGGCGTACTGGGTGGTAGCCACTTGACCCGCGTTGCCCATGTAGGGCCGCAGCAGCGCGCGCTCGACGAATTCGGCCGACAGGGGCGTGGCGGTCACGTTGCGCAGCAGGATCGCGTTGGCCGCCCCGGTGGGAACCGGGTCGACCCCTTCCGCCGTCTGGATCTTGGCCAGCAACAGCGTCTTTCGGATGGATTTGGCCATTATTGGCTCCGTAAGTATCTGAATTCAAGTGGTCAGCTGGCGCCACCGCAGTCGCACGGCGACGTCCGCTCGACAAGCACGCGCTCGCCCGTGGCGGGATCGCGCACGTAGCTGCCGCCCTGGCCGTGGAACTTGTCAGGCGCCGCCGCGGCCGGGCTGATCGCTGCGGACGGGGTGCCGACTGTCTCGGTATCAGCATCGGTCTCCGGCGCGCCGGCCGGTTTCATTGCGGACATGCTGTTCTCCTTCGGGTGCTGGGGCGTTACGCGCCCAGGGAATGCTCATCGGTCTGATAGGTGATGCGGTAGCGCTTGGTGACCACCTGCCGACGAAGATCGCCATTGGCGTACTTGGGCTCGTCCGTGCCGAACTCCACGATCGACACCATGTTGGGCCCGGAATACCCCATCACGATCGGCTGCGCTGCTTCGAACACCTCCTCGGCCAATTGGAGGTGATCGTCGCCGCACGTATGAACGATCAGATGGATTTCACGCACTCGAGTGACACGCGGCGACAACAGCTCCTGGATCGACTCGGCCCCCAACTGCACCGAGACGACCTTCGGGTCCTCGCGCGAGATCGCGCGCATGGGGGAATTCTCAACAGCTGCCGGAAAGCCTTCGGATGCCCCCGCGAGGGCCAAGCGAAGGTCCTCCACGTACCGCTGCGCCAACGAGGTCATGGCAAAAGCTCCAACAAAGCTCGGGTCCAGTACCCGTCCCCGCGCACGGTCGGCTCCTGCCGGACTCGGTAGAGCTTGCCGCCGATCCTTACACGGGAGTGGTACTTAAGGCCTGGGGCCGACGCCGTCGTGAATTCGATCTCGTAATCGGTGGAGTGGACCAAATTCGCCTCGTCGATCACATCGGGCCGGTCAAACCGGACCATGAAATCGACCGCGGGGACAACGCCGTCCAGGCTGGCAAGCTCGCGCATCCCGGCCTGGTCGAACGCTTCATCAAATATCGCGTTGTCCCACATGGTGCTTACGACGCCTTCAGCCGGATGACGGCGTTCGGCCGCGTGTTGATCGTCAGCGGGTTGGACTGCACCTTCAGGTCGACGCCCATGCCGTGCTGGAGAATCTCCTGCGAGGCATAGAACGGCAGGCCCGGGGTGTTGACCACGTCGATGTGGTTGGCCGGCGCGAAGCGGGTCTGGAACAGATCTTCGGTGACGATCGGCACCAGGTAGCCCTCGTTCGGATCGAGGAAGGTCACGGCACCGACTTTGCCGTAGTACTCCTTCCACTCGACGTCTTCGAAGATGAAGCCCTTGCGCATGTCGGCGCGCAGGAATTCGCCGTCCTTCCAGCGGTCGAACGCCTTCTCGACGGAATCGTGGCCGGTAAACGCGTCGTACAGGGCGCGCCCCATGATGCCGAGCCAGCCCTTGATCTGGACGGCGCCGGCGAGCGCGTCTTCGGCCTGGCGCTTGGCGTCGAGCACCTTCTGGCGCACCTTGGTGGTGGCCGTACCCAGCGCCAGGTTCACCGTCTTCTGCGTGTAGCCGAATCGGTCGTACAGATCGAGCAGCACGCGCTGGCCGTCGGCATCGAAGATCTTGCCGGTGACAGCACCCAGGCGATGGTAGGCGAGCGTTGCGTTGATCCGCGAGCGCAGCTTCACGGTGCGCTTGTTGACGATGCCCTGCATCACCTCCAGCTCGCTTTCGGTGCCGAACGCGCGCACGCCCTGGATCTCATCGGCATAGATCGTGTCACGCAGCGGCAGGTGCAGCGTGTTGAACGGGATCAGGTCGCGGCGGTCCTTCTCGGTGGTCTGGCCAGGCGAGCCGCGGGGAGAGTCCGGCACCAGCGCGAGCTTGCCGTTTTCGCGCTCGATCGAGACCGTCAGCGTCGAAACGCCGTCTTCGTCGAACATGCTGTCCAGAGTGGAGGGCACGGCCTGGCCTTCGGGCTGGACGTTGAGGGCGGCCGTCAGGGACGCCAAGGAGAACGCGTTGTCGCGGAAGATATCGATGTGTGCCATGTTGTAGGCTCCTGAAAATGACAATGACCCGCCTAAGCGGGCCATACTTTGGTCCTTGAGCGGGGTTCCGATGGCGCGAATTAGTCGCGGACGATCAGGAAGGTTGGGGCGAAGTCGGCGCGGGCTTCTGCGTCCAGGCCGGTGAGGGACGTGGCCGCGACTTCCGCGAGGCGGACGATGGCAGTCGCCGGCTCGGGGTCCGTCGAGATGTCCGCCGCGCCGTACAGCACCGCAGCGGCCTTTTCCGTGCCATCGGTGCCGGCGGGGTTATACGCCGCGTATTGCTTGGTGGCAGTGATCTGCCCCAGCACCTGGCCGGACGGGTAGCCGGTCGCCGTGGCGGCCAAGATGATTTTCTCGCGGGAGATCTCGCCGGCGCCCTCGGACAAGAGGAATTCGGCGGTACGGGCTTTTTCGTGCAGGATTTTCATACGTTCTCCAGGGTGGTTGAGTGCTGCTTAGGACGCGCGGCGGCGTGCCGCAGCACGAGCCTCGTAGAAGTTGGTGATAGAAAGCGCCGGGGCCGCCGAGGCCGGGTTAGCGTCCGGCCGCTGCCTGTTGTCGACGGTTTGCTCGGAAGCCGCGGCCAGAGCGTCGAACAGCCTTGCCCGGGTCTGGTCCACCGAAAGACCTGCCGCGACAAACTCGGGTGCTTTGTCGGCCATCTTGGCGGCCAGGCAGACGCCGGCGATCTCGGCCGCCTGGACGATTCGCTCGTCCGCCCCCTCTTTGCTAGCGAGGCCGCAGGAAAGTAGTACGCCCTCCGCGAGATGGGCCACACCGGCAGTCCGGCAAGCGGCGTATACGTGGCCGACAAGGGCCGTGGCCTGGGCCGCATTGGCTTGAGGCTCGGCGGCGGGCGCCAGCGGCGGCGGCGCATCTGCCGTCGTGGCAGGCGGCGGAGCGGGGTCGCGGGGCGATTCGGCCTCGAGCGCATCCAGCATCGCAGACACCTCCGCCGGCAGATTCTTATGCTTTCGGAGCACCTCGGCGGCCAGATCGGACGACATCTGGAGGCGCACAGGATCTTCGATAAGATCGCAGAATCCCAGGGCCTGCGCCTCCAACGCCGACATCCACGTGGTCGCGTCCATCATTTCCACGATCTTGTCTGCATCCTGCCCGCTCTTGCGTGCGTAGGCTGCGACAACCCCGTCGCGGACCCGGTCCATCATGTCCGCGGTCGAGCGCAGATCCTCCGCCGTTCCGCCAGCAATGGTCCAGGCGTTGTGGATCATCAGTTGAGCGTTCTCTGGCATGATCAGCTGATCGCCGGCCATTGCGATCAGGGACGCCGCCGATGCCGCGAATCCGTCAACCCGCGTCGTCACCCGGCCGGCATAGCGCCGCAGCGCGTTATAGATCGCGAGCGCGTCGAAGACGTCGCCCCCGGGGCTGTTGAGCGACACCACGATATCGGCGCCGCCGGCCGCCGCCGCGTCCAGTTCTGCGACGAAGGCCTCGGCAGTGGTCCCCCAGAAGCTGATTTCGTCGTAGATTCGGATTTCGACCACCGGTTTTTCGGCCTGCGCCTTCGCAGTGATCGTGTACCAGAGCTTCTTTGCCATGATGGCTCCATAGTTGAAATTGCTGCGGCTATTCCACATCGGCCGGCGAAAGAACCTTGCCGGCCGATGTGGACCGCCGCGGATCGCTGTCGAACACCGCCCGCGCGGCGTCCGCCGCCAAGTTGTCCGCTTCGATGTCGGCGGCGACCTGATCAGGGTCATCACCCTGGGCCAAGATCACCGCCGAGCGGCTTGTGAAGCCAGATCGCACCTGCATTTTCTTGGCCTCAATGTCCTGCACCGGATGGAAGTACGGCCAGCCCTGCGGGACCCAGAGGACGCGCAGCCACTCGCGGCGACGCCGGTGGTAATCCGGCATCGGAATGGTGCCGGCCAGCGCCAGCGCGTCGATCCAGGCCGCCCATACCGGTCGGCAAAATTGATGAATAAGGCAGTGCCACTGGTATTGCTCGATCAGACGGTGGAACTCGTTCACCAGCACCCGCAGCGCCCGATCGCTGATGTTGCGCAGGTCCCCTGTCGCCAGCTCATAGGGGATCCCGACAGAGGCGAAAGCCGCCATCAGTTGATGCCTCATGAAACTGTCGTAGTTGTTATCGGCCCCGGGCGGCGTCGAGAACGTCACCTGCTCGCCGGGCGCCAGCTCCTGCATCGTGCCTGGCTCCATGGAAACCAGCGGGATTCCGTCGTCATCCTCGACATAGTCCTCCTGCCCGCCCGTCAACGGATTGGTCGGATCTTCATCAGGATCCGGCCTGGTAATGAAGCCAGCGAACAGGTTGGAAACCTCCTGGCGGTACATCACCGCGTCATCCAGGTTGTCAATCGACTTCAGACGCAGCAGCACCGTTGCAAGTGCCGGCACCCCACGAACTTGGCCCGGCCGCTGCATCTGGTATGCGTGGATGACCTGGTCCGCCGGCACCGACACAATCTCCTGGGCAGGGCTGGACCGCCCGAACTCGCCGGGGTGACGCCGCCACATGTGGACGGCTGTCCGCCGGCCGATAGCATCGAATTCGATGCCATTGACCACCTCGCCGCCGTTGGGCAGTGGGTACGTGCGTTCCACCGGAACCTGGTCACCCTCAATCAGCTGCAGCTGCAGCGGCACCACCAGGCCGTCCGACGGGCGCCGCCGACGGAACCGACAGAAGATTTCCCCCGCGGTGAAGATAGATCGGTCCGCCAGCGACTGCATACCGTAAAAATCCAGACGCCCGTCGGCATCCGCCTCGACACACCAGTCCGCCCACAGCTCTTTCAAGAGCCTGCGCACCGACTTGTCGGGGTGCTGCGGGTACGGCTGAATTCCCGTACCCACCGCATTGCTGTCCCACTTGCGCTCGGCGGTAGACGCCCACGGATCATTGCGGACCGCATCCCTGGCTCGTCGTCGCTGCAGGGGCAGTCCCTGCGTCGCAGCCGAGTTCGGGCCGGCCGCAGACGGATTCCAGTTCTTCGCGCGGCTGCCGGTCGCGCTGCCGCTTTCGTAGCTGGAACTCATCTGTGCATTCAGACGCCGCGGCACCAGAAGGCCGGACCGGCGGTGCTTGGCGTAGCTCATCGAATTCCCTTTCCGGCGCTGCGCAGTCGAAACTGTCGCGGGCGCCGCTTGCCCTTGTTGATTTCTGCGGATACGTGCGCTCGCGCTCGCATGAGTTCGTCGATGCTGCGAAAGCGCACGCGCTTGCCGTCGTACTGGACCTCAAGCTGGCTGCCCGCGATGGCACGGTCCAGCTTTTCGAGGTCGGCTTGGGTGTACGCCATTTTTGTCGCCCTGTTCTATAGCCGAGGTTATGCCCGCAGCACGTTCTCTACCTACGGGCCTTCAAATAGCTGGAGGAAGACGATCGGCGCCGGGCCGGCCGAGGCGGCGCCCGGGGCTTGGCGGGCGCCGCCTCGGCCGGGACCGCCGGTGACGGTCGCCTGCCGCGCGCGGCTGGCGGCGGCGCGTCATCCGCCTCCACCGAATCGGCAGGCGGCGGCAACGCGTCCAACTTGGCCGCCATCGCGTCCCACCACGCCTCTGTCTTGCGGGTCAGGCCCAGATGCTCCGCGACCCATAGCGCATACACAGCGCAGTCCCAGGTTTCCACCCGCTTGCGAATCGCCGTCCAAAGCGTGCGAACACCCGTGGCCGTCTTGCGAGCCACCCGCACTTCGCCAGAGAACTGGCGAAACCACTCGTCGGACAGGTCCGCGGACAGGTGAACGTATCCGGGCCCGGGAGATTCGATCGCCAGCCGGCTATGTAACAAGTCCTTCGCGCGGTTGGTTCCCACATGCCACAGGATTACGCCTTTCTTCACGCGCTTGCCGCGCCAGTCGATGTCGACCTGGCCAGCGCCATCCTTGATCGCCTTCTCGCCGAAGGGGCGTCCGCGCACCGCGTACACACGCCGCGCCTTATTGCGGCGGGCGAAGTCGTATACGGCATTCGAATAGTGCCCCCCGGAGTCGATCGCGGTCGCGTAGATACTCATCTGCTGCCCGCCCTCGTGCTGGAACCGGCGCTCAAACAGGTATTCCGCCACGCTGTTCCAGACCTCGTCCTCCGCAGGGTTGCCGTGGAAAATCTGGTGATCTACAGTCCACATTTCGCAGCCCCGGCCGAAACCCCAAACCGCGACCTCGACGCGATTGCCCTGCGTGTCGCAGCCGGCCAGCAGCAACGTGCAGCCCAGCGGAACCACGTTCTCGGCTTGGCCTGGCAAGCGGTACGCCTCAATTTCGGCGCGCCGCTTCAACTCGTCGGCCTCAATCTTCTCGATTTCGCCTTCCCAGGCTTGGCCCAGGGTGGTATTCCAGAAGGTCTTCAGCGGCTCGTCGTCGCCCTGCTCGGCTTTCGCATAAGCATCCAGGAACTCCCGGACGATCTTCGCCCAACTGACCATTGGGCTATAGGCGGTCCAGACATGGAAGGCGACCCGCTTGTGCGCCGGGATAACGTCGCCCGCAGCGTCGCGGAAAACTCCATCTCGGTCGATAGTCGTTCCATCGGACCCGTACCAGAACCCATCCTCGGCCGCGGCCAGATACTCGCCCTGTGCGATCAGCGTGCCGCAGTGCGGGCACAGATGCCGCACCGTCTCGGGGTCATCGTTCAGCCATTTGAAGCCGTGGGGCTCGTCCTTGCCGCCCCAGGTGAGCGCGTGATGCTCGTCGCAGTGCGGGCAACGGATGTGGTAGTCATACCGCGCATCCGCGCCAGCCGCCCGCTTTTCCATGAGGCATGTCTCTTTAAGCTTTGGCGTCGAGCCGATCACCATCTTGGGAAACGTCGCGCCCTCCAGGCGTTTGGCGGCCAATTGGCCCGGGTCCCCTTCCCCGTCAATGTTGGAGTCGAACGAACTGAATTCGTCAAGGATCGCCACACTGACCGACAGGCGACGATAGTTGTCTCCAGCCCGGCCGCCCCGCAGGTGCAATGCACTCCCGATGAACTTCTTCACCAGCAGTGTGTTGTCCTTGTGGCGCGCCAGCCGGGTCGGAAAGATCGGATGCATGACTTCCACGTCACGCAGCATGGGCTCCAGCTCGGTCTTGACGAACTCATCCCGCGCGCTGTCGGTCGGCTGCCAGAGCGCCTGATTACGGCGCCGATGCTCGGCGAAATACCCGACCGCGGCGAGCACGATCTTGGTGTAGCCGACCCGTGCCGACTTGATGACATCAACTTCGTGTAGGTCATCGCTACCAATACACGCAAGGATTGCGCGCTGGAAGGGCCACGCCTCCCAGTTCTGCTCGACGTAAGACGACTCGGCGGACAGGTAAAAATTTCGTTCCGCCCATTCCCGAAGCGTCATCGGCTCCGGGGCACCAAAGGATGCGAGCCCGCGACGAAGCGCGCGGGCAACTCCCGCGCGGTTGTCTTCTACGAGCATCATTCACCCTCGTTATCATCTTCCGACTCAATATCCTCCAAGGACAGGGCGGCCACGGCGTTGCGCGCCTTGGCCAGCTCGCGGCGAACAATCGTCAGATCCGCGTCGGTCAGGTTCGGCAGGCGGCGCTTGAGAATGCCGGGAATCGCATCGAACGTGGCCGCCACCTTCGTCCCGGCGCGCACCAGGACCTCCTCGAGCACCGAGACGGGCGCAAGTTCGCCGCGACGCTCGGCGTTTTCCATTTCCACCTTGTCAGCCTGAGCGGCGTTCAAGCGCGCCTTTTCTTCAGCGGGATCCAATCCCTTTGATTCGGGATCCCGGTTGCGACCGGCGGCAGCGTCCCGAAGATTTCCGCAGTACGCCAACAGCCAGTTTCCCAGCGTGTCGCCACTGGTGAGCACCCCGCGCATCAGCAAGCCGCTGATAACGGGCTGGGTGACCCCGACCAGCTGCGCGAACCGTGCTTGCGTAGTTTTCTTGTCCAGGTCAATCATCTTGCAGTCGCCAATGCAGCGTCCAGGGCGGTCGAATACTCCACATCGAAGCGCTCGCCATACACGGCGGCCGCTGTCTCGTAAAGCGGCAAGCGAGGCGTGTACTGGGGCTGCTCTACCGCCAGCAGGACTGGCGCCACATCGGCCCCGTGCGTACCTGTCTTGCGCCAAATGCCGGCGGGTAGGACCTGGCGCCGGTGGCCGCTCATCGACCCCTTACCCCGCGAAATGAAGTACTGGACCCCGTTGATGCGCCGGTAGCCTTCACGCGAGGTGCCAACGTTCGCCGTTCGCGCTCGACTTCGAGCCGTGGCGTTCGCGCGATAGCCTTGCTCTCCAAACGCCTCGAAGTAGGACAGAAGCCGAACAACCTGCCCGCGGGACATGTTGCCGTAGGCGTCCAGTTCAGCAGCTGCAGCCGGGACAGTAAACATGCCCGCCGGCAGGCCTGCGCGCTGCAACGCCCTTTCCGACCGCTTCAGCCTACGTCCACCGCCAAACACCTGCGGCGCCAGGTAGCGATCGGCCGAAGTGCCCTTGCCGGCCCCGTCGCGATAGGCAATAGTTGCGACGAGGTTCCCTTTGCTCGCGCGTACCACACGCAGCGCATTCAAGGTGTAGGGCGTAGGCCGGTCAAACACCTGCTGGGTTTGCTGGACCAGGGCTTGCCGCACCGCATCTGCGGTCCGGTTCAGCGCGACCGAAGTGGCATACGGCAGCTGGCGCCGCATCGCAGCGTAGTAATCGACGCCGTCGCGCAGCTTCGAAGTGAACTTCAGCATGCCATCCTCTCGCCCATATAACCCCCTCCCGCTGGGCGGAGGGGGGCACCATGCAGCGTCAGCAGGCCGCAAGTCCTTGAAATACCGGGATATCCGGCCGAAATTATTATTACCCCCCTATGGATGCCCCATGACTAGCGAGCGTCCGGGGTTCGAATTACCCTTACCGGACTCACTTTCCCAGGGGCCCCCGCGACCTTGTCACGGCTGGCATGTCGGCAAGGACTGCCCAGCTGGATACTCCGCGCCAACGCAATGACTTTACATATTGAAACCACGTGTTAGGCTTAGGTTTTCACCTGTTCACCGTAACCGTAATGCCACTTTCCGTGACACCCATATGACGATCGATAATCCCGCCCATCGACTCTGGCTATTGCTGTCCGAAGCTAGAACCATTGAGATAACGAAGAACTGTAAACAGGCATGGGCTCAACTATTCAACGTAAAAGCGACTAGTCCTGACGTTTTCGAAAGGCTGGGGAAGGTAATGCAGTTGCCGTCCCAAATCATCGCTGCTCTTAAAGAGGAGCATGAGGACGAACTCACTATCGCCCATTACTGGCAAACCCAACTTGACACGGCGTTTTCACGCCAAAACCTAGCCGACACTTGGCAATCATTTATCGGCAACATAGATAACCACTCAATAAACTATCTCAAGGGCCACGCCAAGATCTTGAATGGCGGCAAGCAATTAAAAGCCCTAGAACTTGATACTTTGGAGCAGGCTCGAAAAGATCTATCCGAACTGTTGGGGGAGGTGCTAAAAGACGACTCGATCCCCGTCTCGATTCGTCAAGCTTTAGCCAGAAACCTACGAGCCATCATCATCTCCCTGGAAGAATACAAGCTCACGGGCTCCGCTGGGGTGTTCGATTCCATAGCCATTCTTTACGGACAGGCCCTCTTCGATGTCCCCTATCGTCAATCGATCAAAGCAGACACGCCGTTCGGTGAGAAGCTATCGAGCATTCTTAGCGGCCTTGCAAATTCGATGACCGTACTTCTTGGGACAGCGCAGCTCACGAACTTGTCAGAATCCATCCTACTTCTCGCACAGAAAACCTAGACTTCGCGAACGACAAAAAGCCCGCAGCATCTGCTTGCGGGCTTTTTGTTTGCTACGGGCGTAGTTGTGGCGGAGTGAATTGTCGCGCTTCCGGTCGCACTTTGCACCTATCTCATGTCGCACTATGCCAGCGATATGACGCCGAATTGCGCACCCCCGGCCGCGTAGGCCGCCGCAGCACAGACCCCATTGCCACCAATTCCTGCACGACGCGCAGGACACCCTGCCGCACGGCATTGCGTTCGCGCGTCGTCAGTTCCCGCCCCCCTGTCGCATGTCGCACCAGCTCAATCATGCGAAAGTCGCGGCCCGGACACGCCGCCATCAGTTCAATGACCTCTTTACCAAACTTCACGTTGCACCTTGTCTTTGAAGAAGCCCAGGTACTGCCTGTACTGGGCGTGGGTTAGATAGATTCCGGTAATTCGGCTGATCCAGTCTCGCGCCCGCTCGGCACGCGTCAGCGGCTCCAGGCCCGCGAAACGCTCATGCCGCTGGGGGTACTCCGCAATAATGATCATGGCTTCATGGCGCGGCAGCGCCCGGTGCAAACCGTCAACAGCCACGGCCTGGTCGATCAGGATGGGGCGGAATTCATCCTCTTCCGGGATGAACTGGGCCATGTTGCCGACGGTCGGCCCGGACCAGCACCAGCGCGCCCAATTCCACAGCAGCTCCTCGCCTGAAAGCCCAAGCCTAGACATTGATCACCTCGAAGCGTTTGCACTTTCGCCCATAGGGCCGACCTTTCAGGCACCGCGTTACGGATTCACCGAAAGGCGATTCCACGACCTTGGCGTGAACGCATCCCGCGCAGCTGCGCCTGACCGCCGCCGTCTCGCGGCTGATGAGCACCTCGACCGGGTTGCGCATTTCCCAGCGCTGCAGGTCGCGGCTCATTCGCGCCGCCCTGCCGCTTGGCCTTCGCCAGCTCGTGCAACCGGGTGAGTTCCGCCTCCAGGGCTAAGCGCGCGCCCCGCCCCCGCTGACGGCCCACCCGCTCGAGATACGGCTGACGCTCCATCAGGGGCAGCCTCTGAATGTGCCGCACCTCGCACTGGAATCGCCAGTCCTCCCCGCTGGTGGCCGGAGGCGAGTGCAGCGGCAGCGGCTGCACCATTGAGGCGGCCATAGGCGCTGAGGAAGCGCTTGCGCGCCCCCGGCCTGAGTTCGTCGTAGATGGCTTGCGCATGCATCAGTACTCCTCCAGCACCCAGCCGCCACCGCGGCGTTCGGGTTGCTTCGTTGCCTTGTAGAAAACGAACCAGGGCAGGACCTCGGCGCAGAGCCTGATCTTGATCTGGCCCTTGTCCGTGGTGTATCCGCCCTTCACTTCGTGGATGGCCATGCGCATGTCGGCCTGCAACACCAGGAAGTCGACTTCGTAGTACGTCGAATCGGCCAGGCGGACACGCAGCGGATGGAACAGCCAGCCCAGGATTTCCCCACGCTGGCGCATCGCCTCGAGGCGCATGGAATACGCCTTCTCGGTGCCGTTCATCTTGTCCTTGGGCAGCCGGCCCAGGGCCTGGAAGCGCTTCTGGGCCGCGTCAGCAGCGATGAGCCGACGAATGGCAGCGGGCGTGTAGTTGCTGGCCATCAGACATGTACCCCGAAGTCAGCGCGCGCTCGGGCCTTCTGCTCATCCGTGAGGTTGGCCGCCTGGAGAACGCGCTTCTTGAAATCGGGGGGCTGCTCACCCGCCTCTTGTCGAAGCCCCAGGACGTTGCCCTTCGCCACAATGCCCGGCCACGATCGCAGCCAGTCCAGTGCGTCAGGCGCAGCCGCGCCCCCGCCGGCGTTGACCTCCGCCTTCGCCTTGTCCATCCAGGACGCCCGGAACCCAGCCCAGGAGTTCTCCGCCGAGATCCGCACGGCCTCAGCCACCGACAGGCCGGCCTTTTCCGCTTCCTCGACCACCAGGTCCCAAGCGGTGAGGGTGAGCGGCGCCTTCTTGTCCTTGCGGACCTTGAGCCAGTCCTGGGCGTGCTGGCGGTCAACGCCCACCGCAACCAGGTCCTTCACCCCGAGCGTGTCCCCTGGCTTCGAGCCGCCCTCCCCCTTGCTCGTCGATTTCTGACCCGGGGTTTCGGACACTTCGGGCGCGCTCGCGCCCCCCTGATGATTCCTTGTTGGTTCTTCTTTAGATTCTTTTATGGTTCTGGGTGAAGCTGCTTCCGGTCTAAATTGCACATTTTTCCGGTCAAGAGCGCCGCCATTTTCCGGTCTGCCTGCATTTTTTTCGGGCGAAGATTTTTCGGGTGAAGATTCTTCGCCCGAAGGGCCTTCGCCCGAAGGGTTTTCGGGTGAAGAATCTTCCGGTAAGGCGTCATCCCGTCGCCAGGCCTGGTAGTTCTCCGGCGTGACGGTGTAGACCGCGCTGCGCTTGTGACGCTTCTGGCGGCTGATTACAGCGCGCTCCTCGAGCCACTTCAGGCACTTCTGCACCGTCCGGTCGGTCAGGCAGGTGCGCTCCACGATCCTCTCAACGGAAGGCCAGCAGACGCCCTCATCGTTGGCGTTGTCTGCCAGGCTGATGAGGACGGACTTTTGTGACGAGGGCATTTGCAACGGCCAGCAGGCCGTCATGATGATGGTGCTCATGGGGTTTCCTATGCGGCGGCGTGCGCAAGCCCGCTCGGGAGGCACGCCTGGGCCTGGGCGGGCGCCGGGGGCGCGTAGCGGCGCTGGAGCCACACCTGGCCCTTGCCCGTCACCAGGGTCTTGAATGACACATGCACCTGACCGTCATCGGCGCGCCAGGGCATTTCGATCAATCGGAAGTAGCCGCGGTCCAGGTACTCCTGGTACGGCTTGTTGTCCTCCAGCAATACGCGGTCGGCGCGCAGCTGGCGGAAGAAGCGGTTCTGCCCGGTGCCCAGCAGCTTGGCCATGTCCCGGATGCTGATGCCGTCGACCGTGCTGCGCACCGCCTCGGCGAACTCAACCTTCGGCTGCTGCTCGAGCAACTGCTGGCGCTGGCGGTAGATCTCGTCCTGCTGGTCGGCTGCCAGCCGGAGCGCGGCGGCGAAGTCCCGGGGCACCGCCGGCGACTGGAGGGCGTCATAGGCACGGATCACGCGCAGGTGGAATGCGGCGCTGATCCACATGGCGTAGGCGTAGACCAGCTCCTTGGCAACGTAGGTGCCCAGGCCCTGCCGGGAGAAGATTCCGGGAATCCCCGGAATCATGTCGCCCAGCTCGGCGATTAGGTCTTGCGTCTGCTGTAGGCGGACCCAGTCCGAGGGCTGGTGCCGGCGCTCGCCCCCGGCGGCCCGGTGCAAGTCGTTCAGGCTGAACCGCCCTTCTTCGTCCTGGCGGATGGCGGTGGTGGCGATGATGAGCGCGTTCATCGGGGCTCCTTTGATTGGGGGCGGTCACGCCAGCGGTACGAATGCTTGAAGGCATGGAAGCCGCGGCGCACGACTTCGAGGTCGGAGCGCGACTCCCGTACAAGACGGTGCGCGGCGTCCAGGCAGACGGTCAGATAACCCTCGCGGCTCATCTGGCCCTTGGGGAACGGAAAATGCCGGCCGATCACCTTGCTGATGGCCCGGGTGTCGAACTCGTCACCGGACGCCATAGCCTCACGGGCGGCATCGAGGGCGGTTTCAGGGACTTCGTAGCCGTGAACGTTCATGCCGCGACCTTCCGACCCTCTTTGTGCATGGCGATCGCCAGCGCTGCGACGTCGGTGTCGATGCCCGCGGCGTCCAGGCCGCCTCGCGGGACGTCGTGACCTCGGGCCAGCAGGAACAGCACGCACTGGCGCAGCAAGTGCTCCTGCGTACCGTAGCGGTGGATGAAGGCTGCTCGGTCTTCATGGACGGCCTTCATCCACGGCGCCCCCGTTCCCCTCTGGTGGTGACCCGCGCAAAGCGGCAGAACGAAGTACTGCACGCCTGGCCGCGTGCGCCCCCGCATGTGATGGACGCTCACATAGTGGGTGACGACGTGATGACCGAACCGGCAAGCGGCACAGCCCACCACTGAGCACAGCAGGTCATGAAAGGCCCGCTCGACGACGTTGGCCGGCTTGCCCTTCATTGCTCGGCCATGCCCTTGAGGCGGCGCGCGACCTCTGCGGCGGCCTGCATGACGACACGGGCAGCAGAGGACACTCGCTCCACCTCGGCGCGGTCGACGCCGCCATCGGCCAGGGCGTCGTAGACCTCTTTTCCCAACTGGCCGTTGGCGACCATCAACGCCGCCACCTGCTCCAGCACGGACATGTCGCTGTCACCGCAGGACTCCGGCGCCTTGACCAGCAGGAAGCCGGCTTCGTGAGCCCAGGCGGCCAGGATCCGGAAATCGCCAGTCATGCGGCAGATTCGCACCGCCTCGGCCAGCGTCAGGTGGTGCGTGGTGTTATTGGGGTTGACCTTGTTGCGCAACACTGCCGGCGTGATGCCGACGAGCGGGCCGAGCGATTCGCTACCGCCCTTGAATTCATGGACCGTCAGGTCCGCAGCCGTGGTGATGTTCATTACTCGATTTCCCGAACGTATTAATTGCGGGGCGTGCGCCCTACCATGTGCGACATGAAGAACAGACTTCAAACGTCCTGCGACCCAACCTGGAACCTGTCGCTTTGCTTGGCCGGCAACACCGGCTGGGGTGCCGGCTGGCCCGGCGTCATCGCGCTACACATGCGCTCTCTCCTGAAATTGGGTGGCCAGCCCCTTAGAATCGGAGATTCCACTCAACCGATTCGCCCCGAAATGGAGGGGGCTGACCATGGCCTTGAAATTCGTTTCCATCACGCAACCGACCGAGGACTCCGAAGAGGTAGGCGTGAGCTTCCAACTCGATTCCGAGTACACCGGAAAGCCCCCCTACTTCATCGGGCAAGCACAGGTGTCTATTCCTCTATCCGAAGCCCTTGAAATGACCTTGGCCGAGATCATTGGGAGCGCCCGCGCTCAGTTGAAGGTCCGGTTGATCGACTGCGCCAAATAGCGCCACCCGAACGCATCGCTGTGGCAATTCGTTCATCAGCGATGCGTTCAACAGCCGGGCGGATGAGCCACAGGACAAGACGGGTGTAGAGGCTATGCATGGACGCCCCCTTGGGTCGACACCTCGCGCGCAAGCTCGGGCCACACCGTCTGCCAATCATGAGGACGCAACGCTTGCCGCAGGACCCGGCGGCCCGTTGCGGTCTCAATTCGTGCGCAATAGACGGGGTCGATCTCTTTGTCTCGGTTGAGCCAGTTCCCGACTTGTTGGGGAAGGACGCCGACCGCACGAGCAAGGGCAGCCTTCGTGCCCAACTGCTTGCATGCGGCCAGCAATGCAGGGCGGTGCGGGTATTGATCAGGTTCCATGTATCGGCTTCTACAGTTGAGATTAAGGCCGATGGTAAACGAACGTTGACCGAATCGTCAACGCTGGTTGATGGAAACAATCAACATTTGTTGTTAAGGTGCGCGCCATGGCAATGGGCAAAAATATCCGCTTCCTCCGACTGGCCAAAGGGCTCACACACGACGCCCTGGGCGCGCTCGCGTCTACGAGCGGGCAAACCGTCGATCAATTGGAGAAACGCGATAGCAAGCGCTCCAACTACGCAGGCGGCATCGCGCACGCCTTTGGCCTATCGGTTGAAGAACTACAAAATGCCGCCCTAGAGAGCGTTGACGACGCAATGCGGCTTCTCGGTGATGTGGCTCGCCGAAATAGAGAAGTGAGCGCGCCGCTCGATACCCACCGACACTTGGTTTCTGAGCCGCAGCCCGAATATGTTGGTCGGGCGGTCTCAGGACGCCTTATCCCCGTAGTAGGCATGGCACAACTGGGCGAAAACGGATACTACGAAGAGGTCGCATACCCGGACTGTCAGGTCGACGGATTCATACTCCACGCCTCAAGCGATCCCGACGCCTATGTATTGCGGGTGCGCGGCGACAGCATGAAGCCCGCGATCCGAAACGGCTGGTATGTGGTCGTTGAGCCTAATAGCCCGGCTGCCCCGGGCGAGTACGTAGCGTTGCAGCTGGCAGACGGTAGGAAAATGGTCAAGGAACTCATCATCCAGCGCCGCGATGGCGACATTGAGGTATTGAGCGTCAACGGTGAGGTGCGAATGAGCCTGCACGCGGGCCAGGTTGAACGTATGCATGCCATCGGCGCAATCGTGCCTCCCAGCAAACACAGAACACACTGACCCGCCCCGCAAGAAGTGTCGCCGCCCATGGGCGGCTTTTTTTTCGCCTGAAACCAACACTTGTTGACCAAATCCAAACTTATGTTTACCATTTCATCAACGTTTGTTTACCGCTCTTTAAAAACCGATGTGCAAACCGTTCCGCACCCGCCGAGAGGCGATGCGACAGGGGAGATTGCGGACGCCCTGGACCAAAAGAATCCGAAAACCGCCCATGCACGGTGGCCGAACAGACTAAGGCCGGCCAGGCGCAGAACCTGGCAGCACTGGGCGCGATCCTCACGGACGCCAAGAATCGACCGATGGCGCGTAATCGGGTTGATGACCACCGGGAATAGACCGGGAACCATGACCGCCCTGGCCTACGGGTTGAACGGCGGCGGACATGCTGGGCAACGCAGCACCTGGAGCCGCGATGAGCGGGAGTCGTCAGGCGGTGCGCTGCCCCAGATTCATCTGCCAGCCCGTTCTATGAGCGATGGCTGACGAATGAACCACGGGGGGGACCTATGTACTTTGTGCTTTTCATCGTTGCTATTGCTCTGAACCCCGTCCTGGCGCCCATCAGCCTTGCAATGATTTGGCTGTTTGTGGTGGGTAGTGTTGGCTACTTGATTTTCTCCAAGGAAAAGCCAGAAGGAGGCCTACGCGCTGACACAGTGCTTGGGCTGATTGTTCTGACCTTTTGTGTGCCTATGGTCATCGTTGAAATGTGGCAAGACCTCGGCGTGAAAGTCCCGTACTCCTTCGTATGGTCAATGGCCAAGTACAGCTTTCTCAGGATTGCGAGCTGAACAATTACTGACGAGTGAACAAGGAGAAAGCATGAGCGAAATGGCAAACATGCTTGTGATGTTCGTCATCGGCTTTGGTGTTGGCGTCATCTACGGACGCATGAAGGGGATGAGCGTTGAGGACGAGTTGAACATGAAGATCAATGATCTCGCTCAGCAAGTACGGATCCTTAAGAAGCGACTCGATTCTGAATAGGAGAACTTTATGTCAGAGCAATTCAAAGACTACGTGACGGGCGGCGCGTTCCATCTGTCGCTGTCCAAGCGTCAGGTTGAGATGCTTGGCCATCTCTATCAATTCGGATCCACCTGGGGCTATCTCTCAAGCTGCAACGCACTCATCGCAAAAGGATTGGCGGAGCGCATTGAAGAGGAAGAGCCGGGCGGCGAAGGAACGTGCCTTGTTGGATCCGGGAAGGTTGTGTTGTCAGAAGCTGGCAAAGCCTTGATGCCGCTACTGATCTTGGCTGGCCTCTACCAACCGTGGGAAATGCCCCAGCCAGTCGAAATACCGCCCGTCAACATCCGCATCAAGCGGCGCGATGAAAGCGAAGTGCTGGAACGCTAACCCCTGCCCACCCCTATAGCGCTGGCAGGTTAAAGAAACTGGAATACCTCCCCACCCCGGGGAGAACGGGAGAAACAGCATGGCTACACCGCAACGAATCGCCCCGCCGTCGCTCAATCGCGGCGTGTTCGGTTGGGACTCGTGCCGCCTGGCCGACGCCTACAGCACCCAGGAGCTGACCGACGCCATCACCTGGATCAGCCACGCGCCGTGCTGCGCCAACCCTGAAACCGGATCGATCTGGCTGCTGAACAAGAAGGCGCGCCGCATCAGCGAGCAGCTGGCTTGGGCTGTTCGCCACCAGATGGAAGAGAAACGCCGCGCCGAGCAATACCCGCTCGGCTACATGCAAGGCCGCGGCGCTGCCTAACCCCCACCCGCCCCGGTAGGGGCCAGGAGAACAGCATGCAAAGCAATCTGATCCTCACCACCGCCCAGGCCCAGGCCGTGTACAGCGCCATGTGCGCGCTTGATGCTCTTGGCCCCGACCACGGCGCGGAGTTCCATCTGGGCGACTGGGTATATGTGCGCCGCGTCCATCTGGACGGCGCTATCCGTATCGAAGACCGCGCAGATGGTGACGACGAGCGCCACGACGATCTGGCCGCCTTCGCCGCCGCCTACGGCCTGCGCCAGCCGCCCGATGCCGCCCCGCTGCTGGAAGCGTTGCAAGCCGCCCTCGCCTACAACGATTCAGTCATGAGCGCCGATGGTAGCGGCCAGTTTTCGTGGGGTCCGATCGCCCGCGCCGCCATCGCCCAGGCCACCGCCTGACCGCCCCACCCGCCCCGGGTGCCGGGGCAAGGAGACCACCATGGAAACAGCAGAAGACCTCTCCTACGCGCTCGCCAAGCAACTCGCCAGCGCCCACACCATCAGCACGAGCTACGGCGATATCCCCCTCGATGACGAAATGCGCGCCGCTGTCGACAACGCAGTGCGGCCCATCCTCAAGCGCCGCTTGAATGCGCGTCTCGCCGACACCGCCGCCAAGGAATGAAATGGCGACCGTCGAATTCCACGATGAAATCGGAGGCGCGTATTTGGACGAACACCCTGCCGGCATCTTCGGCAGCCGGTGCCACTATGACCGCCGCTACTGGCACGCATGGGCGTCCTCACCCGACCCGCAGAAGCGAGATTGCATCCCCGGGGTGATGGACGACTTCGGCACCCTGGTGCCGGTCCCGTCCCCTTCCTACTAACCCTCGCAGTGAGGAAATGACCATGACCAAGAACGACCTCCAAGCCAAGCACATCGAAGCTATGCGCGCCGTCGCCAATGGTGCGGACGTGTGGGCCTACGGCACCGCCGTGGACCTCCGCGAAGTGCAGCGCGCCGCCCCGGAACTCATCACCATCGGCCGCGCCATGATGGCGCCCGACGACGGCGCCAAGCAACAACCGTATTTCGGCGCGATCCTGACCGATGCCGGCCGCGAGTTCGTCGGCTTGCCCAGGCTCATGGCCGCGGCCGCCTGAATGCACCAGACCAACAGGAGAACGCGACCATGGAAGAAGTGACCATTCACGAAGCCGGCGCCCTGCTCGCCGCTACCGGCCGGATCATGATGCGCCATGGCGTGCATTTCGACGTGTTGGTCGGTGACTGCCGTGATGATTGCAGCGATGCCGACTTACTGGAAATCATGGGTAATGCCGGCGTGCCGGAAGAGCGGGCGCGCGAACTGCTCCGCATGGACCTCAGCGACGTGATCGCCGACCTGCACTTCGGCACTTGACAGCCCCGGCTCATGCCCCGCGAGCGGGGTATCGGCAGGCGCTGTTGCCTGGACACTCAGGAGAGAACATGTTCGGCGGTAACGAACCCGAAAACACCATCTTCAACCCCAAGCGCAAGAAGGGCCTCGGCCCCAACTAATGCGCGCCCCTCCCCGCTTTGTAGGGAGGGCCATCAAGAAAGACGCCTGACGGCTCCTAACGGTCTTGGGAAGGGCTCATACCCCCGGCCAAGTTTGCGGGCGTCTCCCTTGATGGCAGCAGTACCGCCCAGCCGATGGGCGCCCTATGCAAGGCGGGCGCGGTCAGGATTGCAGGGCGCGATTCGCTCCACCCGCAGAGGCCGCAACCCGGGATCGCATCCGGGGCCACCAACCATCCCCCCAACCCCACCGGAGCTATCCATGCTCGATGCCGCCATTGATTCCATCCGCAAATTCGCATCTGCCTTGTTCGACGTCCTGGAAAACACCTGCAAGGTGATGCGCTGGTAAGACCGAGGCGCACGGCCTGCGCCATTTCAACCTGAGATTTATATAGTCATCATCGAACCCGGCAAAACCTACAAGCTGCAGGGCCCGAAGGGCAAGCCGCCCGTCGAAGTCCTCGTTACCGCCATCAAGCCCCGCGGGCGCGGCCACAGCGTCGAGCACCTGGTCGGCAAGAAGAAGCTGATCTGCGGCCTGGGCAAGTTCCAGGCGCAGTTGGCGCAGTAGGCGCACATCTACATCCCCTCGGCACGCCCGAGGGGGCTTCGGAGAGCGGGCTGGATAGCCCGGTATCGCTCACGTGGTGGAGCCGCTGTCTTGCGCCGGCGGCTGTGCGGCGCCAGCCCGCTCTCCGAAGTACGCCAGCCTGAGGCGCACAGGCCCATGCCGGACATGGAAAAAGCCGGACTCCCCCCAAGTGGCGCGCCACTTCCCCTCTGGGCTGACCTGCCCGCCAAGGACCTCCATGAAACGAATCGTCATTCTGGCCGCGGCCGGCCTTGCCGCGGTGCTGGGCGCCACCTTTGCGCTTGGCAATGTCGTCGGTGCCCGCGACCGCGAGCTGCTCGCAAAGGACGACAAAGGCCGCGCCACGATGCTCGCCCGCAGCTGCGGAAAGCATGGACGGCTGCTGCTCGACCCAGTGCAAAACGAATACGTATGCGCGTGGACGAACCCCGACGGCGCCACTGTCACGGCCGAAATCCCGCAGTACCCCTACCTCGACCAGCTGGCGCAGCGATAGCCGCCGGCCTGGCCCACGCCGCCCAGCGCGGCCCGAAGCAATGGAAAGAGATTGAATCAATGCAACATACACCGCCCCCGGGTGCCTTCCCCCAGTACCGAATCATCGGTCTCGTCGGTCGCGCCGGCGCCGGAAAGGACACCTGCGCCGACATTCTGGTCAAGACGCGTGGCTTCGCCCGCCTGGCCTTCGCTGATGCACTGCGTGATGAGGTCGTCGCGGCGTTCTCGGTAGACGTCACCCCCTTTGCCGACAGGGTACTGAAAGAACGCCCGACGCCAGCCCTGCAGATCCGCCGAAGCGCCGATGAGGAATTCATCGCCCGCGCCAAGGCATTGGGCTATGACCTGTGGGCCCAGCGCTCCCCGCGAGAAATCATGCGGCTTTGGGGCACGGAATACCGCCGGCAAGTCACGGCGGACAACTACTGGCTGGAGCGCGCCAATGACCGCGTCAATGCCCTGCTCGCCAGCGGCATTCGTCGCATCTGCTTCACCGACGTTCGCTATGCCAATGAAGCCGCCTACGTAACCGAGAGCCTGCGGGGCGACCTGTGGCGCATTCGCCGCCGGTCGGCGGATTCCCGGCACGCTACCCACAGCAGCGAATCCGACCTCGAGCGCATCCAGTGCAAAGAGGTCATTCACAACGAGCTTGGCCTGCAGGAGCTGGCCCTGGAGGCCCAGGCCGCGCTCGTGCGCCATGTCCTGGAGTAGCCATGCCCTCAGTCAACAAAGTCATCCTGGTCGGCAACCTCGGCCGCAACCCGGACATTCGCTATTCCCCCGACGGCGCGGCAATCTGCAGCATGTCGATCGCCACAACGTCCACCTGGAAAGATCGCGCCAGCGGCGAGCGGCGTGAAGAAACCGAGTGGCACCGCGTGGTCATGTACAACCGCCTGGCCGAAATCGCCGGCGAGTACCTGAGAAAGGGTCGCTCGGTCTACATCGAGGGCCGCCTGAAGACCCGCAAATGGCAGGACAAAGACACCGGCGGCGACCGCTACAGCACCGAAATCATCGCCGACCAGTTGCAGATGCTGGGCGGCCGTGACGGCCAGGCCGACGGCGGGCACGCCGCTGACGCGCCAGACGGCTCTGATGGCCAGCGCCGCCATCGCCCCGCGGCCGCACCGTCGAACGACGGGACCGACCCCGACATTCCCTTCTAGCACCCCACCCGCAGGAGAACGCCATGAGCGCATTTTGCGTATTCGGCATGACCGAAACCCTCGCCAGGAAGGCCGCAGAACGTGCCTGGCAGAAGCACCTGGAAAGCCTGACCAAAGAGGCCCGCGCCTGCCTGACGCCCGCCGACGAGACCGAATGGATCAAGGTCAAGACGGAGTACCACCTGAGCAAAGGCAAAACGATCCAGCTGTCCGCACCGTTCGACGCCCCGCAGTTCGCCCAGGATTTCATCAAGCTCGCCCGCGCCACCGGCCGAACTTCCCGCCTGGAAGTGATGCGGCGCGCCCCTCTGCTGGACAAGAACGGCGCCCCGCGCATCAGCAAGGCCACCAAGCGCCAGATGATCGGCTGGGTTCCTCAATAACTCGACTGGAAGCCTACCCCCATGTGGTTCAAGAACCTCAAGATTTACCGCCTGCCCTCCCCGTGGCAACTCTTCGGCGATGACCTGGAGGCCGTCCTGGCCCGCCACGCCTACGACGGCGGCAGCAACCTCGAAATGCAGTCTCTCGGGTGGATTCCCCCGCGCGAGGGCGGCGGTCTGGCGCACGTAGTTGGCGGGCAGATCCTCCTGACCCTGCGCGCCGGCCAGAAGCTGCTGCCGCCCAAGGTGGTCAACCAGGTCGCCAAGGCCCGCGCCCAGGAGATCGAGGAGCAGCAGGGCTACAAGCCGGGCCGCAAGCAGATGAAGGAAATCAAGGAGCGCGTCACCGACGAACTGCTGCCGCGCGCCTTCAGCGTGTACCGCGACACCCGCGCGTGGATTGACCCGCTCAACCGCTGGCTGGTGATCGACGCCGCCGCGTCCTCCAAGGCGGACGAGGTGATCGGGCTGCTGTCCAAGTGCGTTGACCCCTTCCCGCTGGAAAACCTGTATGTCGCTCAGTCGCCGGCCTCGGCCATGACCGGCTGGCTGGCCGAGGACGAGGCGCCGAACAATTTCACCATCGACCAGGACAGCGAACTCCGGGCTTCTGGCGCAAGCCGGGCCGCTATTCGCTACCTGCGGCACTCCATCGACGCTGACGACGCCCGTCGCCACATCCAGTCCGGCAAACAATGCACGCGCCTCGCGCTGACCTGGGCCGACCGCATTTCGTTCGTGCTGACGGAAGAACTGGACGTCAAGCGCCTGGTGGCCTTGGATGTGCTTAAGGAGGGCAACGACACGATCGCCGCCAATGACGACGAGAAATTCGATTCGGACATGACCCTCATGACCGGCGAACTCGCCAAGCTGCTGGCCGAGCTGGTTGACGCCCTTGGCGGCGAGAAGCGTATCTGACAACTGGAAAGAAAAATGGCTAAGAAATCCAAAGACGTGTACGGCGCCGAAGGGCAAAGCAATCTGCTCACCTTCGACCCCGACAAGCTGGTGCTGGTGACCGATGAGTCCAGCCCGCTCTATGACCCCCGCGTGCATCTGCCCGTAGACGAAGCGATGGCTCGCAACATCGACTTCCAGGGCGTGATCGAACCCATCGGGATATCTAAGAACCCGGAAACCGGCGAAACCGAAGTTGTATTCGGCCGGCAGCGTGTCAAGGCCGCACGCCTCGCCAACCAGTGGCGCCACGACCGCGGCGTACCTCCGCGTCTGATTCCTGGGGTTGTGTGGCACGGCGAGCGCAAGGACGCCCTGGATGCCATCGTCGGCGAAAACGAAGCGCGCACGGCCGACACACCGCTCGGACGCGCCGAGAAGATGCGCCGACACCTCGCCCTGGGGAAGGGCGAAGACCAGATCGCCGTGATCTACAACTGCTCCGTCGCCACGGTGCGCGACACGCTCGCGTTACTCGATAGCCCCAAGGTCGTGCAGAACGCGGTCGAGGCGGGACAGATCACCCTCACGCACGCCAAGGCACTTGCCAAGCTGCCTGTAGCCGAGCAACGCACGAAGGTCGCCGAGCTGGTCCAGGCCGGCCAGGGCGTCAAGGCGCACGAACGCAGCCGCAAGCAGGCCGCCGTCATGGGCGAGCGCCCCCGCGTGAAGTCCCGCAAGCAGATCCAGGCTGCCCTGGAAACCTCCCAGGGCGACTATGCCGCCGCCCTGCGCTGGGTTCTGGGCGAAGAGGGAGGGGCGGCCGCATGATCAAGCTCACCGACTCTAATGGTGCAGCCCTCTACTTGGCCCCCGCCGCCATCGCGAGCATCAAAGAAGCCGGCCCCAGTAGCGCTTGGCACGGCATCCGGTCCTACGTTCGTACCTTCGACGGCAAAGCCTACGAAGTCCAACAGGACGCCAATGAAATCAACGCAGCGGTGCAAGCCGCCGAGAAAAGGAGCGAAGCATGAACGCCCCCGCCCCCAAGACCAGCCCCGACACCGCTCTCGGCAACCTCATGGCCGCCGCCCTCGACGTTCCCGCAGCCCCCGAACAGCCCGCGGTGCCCGACGACACCCTCGCCCGCACGGGCAACACCGCCCGCGACCAGGAGATGTACGCCGCCGGCATCCGGACTGGCGAAGAGAACGCCAAGCACAATGCGGCGATACGCGCCGGTGCCAGCTGGCAGCCGATCGAGAGCGCGCCGAAGACGGGCTGCACTCTGCTGCTCGGCTACTGGAATTCGCATGGCAAGTGGCGCACCGTGCGTGGACAGTGGATATCCGCCGAATACATCGCCTAGCACTGGGAAGAACCGGACGATGCAGAGGAAGGATGGTTCGAAACCGCCGTTGAGGCCGAGGAAGTGCCGAATTGCTGGCGGACCACCCCGTCGCATTGGCAACCGCTTCCCGCCGCCCCTGGCGCATCCACGGCGGGGAATCAGCAGCCCGCCCGCGACTGGGAACTGACCTGCCACGAATGCGACGGCTCCGGCCACGTATACGTCAAGCACCAGGTCGCCGAGCGCAAAACCGACATGCAGGAGTTCAAGGAGGAATGCGAGTGCTGCGAGGGGCGCGGCTTCGTGTTCGCCTTCCAGGACATTCCGGGGATCGAGGAATACGTGAAAGCCTGCCGCACCGCTCCCGCTGCTGGCGATGCGCTGGATGCGGCGCGGTGGCGCGCCTACGCGAAGCTGTTCCCCGAGGTATCCGCCTCGTTCCTTGCAACGCACGCTGTGGATGGCGACGATCCGCTGCCGACGATCAAAGGCGCGTCGATCACAGGCGGCTATGTCGTGGTGACGCCTGCCGGCTGGGATGCCGACAACGCCACGAAGCTGCGTGACGCCATCCTGCGGCTGTTCCCCGTCAACCCCGTGCACACGCCGCGACCGAGCGACGAGCTTGCAGCCCAACGTAAGGGGGATGCGTGATGGTAGATATCGATAGCCTCCGCGTCATAACCCGTCAGCGGTGGGGCCGCGTCACGGCTTTCCGCCTTGGGCAGATTGCCGCCGAATACCTTGGATCGGTTGCCGTCGACGCGAACCCCTACCGACCGGAACAGCACTCCCATCGCAACTATCTGGAGGGAATCAGCTTCCACCAGGCGAAGGCCGCCCAGCAGAGCGGCCAGGGCGCGGGGAGCCAATCATGAAGCCCGCAACCGCCGCAGCGGTAGCCGCTGCAACCTCTATCGCCTCCTACGCCACGGGGTACGCCTCTGCGCATACCGACCACAGCTTGGGAACGCCGTTTTTCATTGGCTTGATGTTGGCCGCAGTTTTCGCTGGCCTCGCCTTCGCAGCCGTAGAAAAGGACTGATCCTATGACCCAACAAGACGACATCACCCAGCGCCTGCGCGACAACGCGGACCTGGACGAAGCCGAACACGGCAATGCCCGCGTGGTGCAGCTGGAGCGCGAAGCCGCCGACGAGATCGAACGCCTGCGCGCGCAGCTTGGACAGCGGGGCGCCCCTGTAGCCGATGAGCGGGCGCTTGACCTGCTGGATACGCTATTCACCGCCTACGAGAACGGCACGCCGTGCTACGAGGAACCGGACAGCCAGGGCGGATACCTGGGGATGGCGTTCCGCATTGATGACGACACATTCCGGGCATGCGCCGACTTGTTGAACAAGGAGCGCCCTCGCACGGCTGGCGCCCTGGCAAGCGCCCCTGTAGCCAAGCCGAAGTGTGCGCCGATTGATGACGGCATTTGCTGGTCCTCGAAGGAAATTCAGCGCCGCCAGAAGGAGGAAGACGATGCCCGCGCCGCCTATTACCACAGTCGGGCAAGCGCCCCTGTAGCCGAACCGGCAATCGTTGGCTGGCGCGATCCAGATTGCGGGCGCATGGCGCAAAAGGGTCCGCCCCACGGGTACAACCGCTACAGCGAAGCGCTGATGACGGTTGCCGAACACCGCGCGTTGATGGCCGCCGCTCTGGCAAGCGCCCCTGTAGCCGGGGAGGTGCAGCCGGTGGCCGTCACGGATCACCAAGGCGACGTTCACTGGAGGCATGGGCGCAAAGCGGGGATCGCGCTCTATGCCGCGCCCCAGGCCAGCGCCGACGCATTCGACTTCGTCGCCCATCTGGCGCGGCAAGCCGAATTCTCGGCCCGCACCTTCGGCCCCGGCGCTCGCGTGGCCGGCGTCTGCGATCACATCCGCAAGGAACTGATCGACGTCGAGACGAGCGGCGGCGACCTGAAGGAATGGGTTGATGTGATCATCCTGGGCCTGGATGGCGCATGGCGCAGCGGCGCCACACCGCAGGAAATCATCGCGGCCATCGTCGCCAAGCAGGCGAAGAACGAGGCGCGCACCTGGCCGGACTGGCGCACGGTGGACCCGAACAAGGCCATTGAACACCAGCGCACCGCCTCCCCCTACACCTGCCCCAGCGGTGACGGCTCCCTGCGCCATCCCTGCGCAGCACATCCCGCCAAGGCCAGCGGAAACGGAGGTGAAGAATGGTCAGATTCGTGACAATCTCCCGCGCCTCGGCCATCACGGGCTATACAGAGGATGCGATCCGCTCGAAGATTCGAGACGGAATCTGGCGGGAAGACAAGGAGTGGATCCGGGCGCCGGATGAACGCATTCTTATAGACATGGAGGGCTACGAAAAATGGGTAGAGACGGGAGGGGTGTTAAAGCCGCCTCGGAAAGCAGTATCGAAATCACGTTCCAGTACAAGGGTCGCCGCTGCCGTGAGCGGATTCCTCTCAAGCCCACGCCCGCTAACCTGAGGCGGGCCGAGCAGCACCGGGCGGCGATTCTGCACGCGATTTCGACGGGCGTTTTCGACTACGCCGCCACATTTCCCAATAGCGCACGCGCCGGAACCTACGCAGACACGCCGGGACAGATCCTATCGGTTGAAAAGTACCTGGACGGATGGCTTGACGCGCGGAAGCCGACCTTGAAATCCAGCACGTACCAAGGGTATCGAAGCATTGTGCTCGGGCAGCTGATTCCCAAGTTCGGCAAAGAAATGCTCGGCGACCTGAAATGGCCCGCAATTAAGTCCTGGCTCGCAGGCCTTGGCGGCGACAAGCCGGTGAGCAATAAGCGACTTTCCAACATTCAAAGCTGCCTCCGGTCGGCGCTGAATGATGCGGTCGAAGACGAGCTACTAGACGAGAACTGCATGCGGGGTCGGCACTACAGCAGGCAGGCCCAGCCGGTTGAGGAAGGCGACGACGATGAGGTCGATCCGTTCACGCCCGACGAGCAGGCGGCGATCCTGAGCGAGTTGCCGGAACAGACCCGCAACTATGCCCTCTTCGCCCTCTGGACGGGACTTCGGCCCAGTGAGCAGATAGCACTGAACTGGTCAGACGTAGATTTTGCCCGCGGCGTTGTGCTGGTGCGCAAAGCCATCACGCGGGCCGCTAAGGGAGTAGCAGAGCTTCCTAAAACGAAATCCAGCCGGCGGGAGGTCAAGATATTGGCGCCGGCCCTGGCGGCGATCAACGGCCAGAAAGCGCACACATGGGTAGGCGCAGAACCTCACGGGGAACTGTTCCGGAACCCGGGAACGGGAGAGCGATGGTCGAGCAGCCAGGCGGTTCAGAAAGTCTGGGCCACGGCGCTGAAGCGTGCGAAGGTGAGATATCGACGCCCGTATCAGATGCGCCACACGTTCGCCAGCATGATGCTATCGGCAGGCGAACACCCCATGTGGGTAGCGCAGCAGATGGGCCACAAGGACTGGGCCATGATCATCCGCGTGTACGGAAAATGGATGCCTTCCGCAGACAAGGAGGCTGGGAGTCGCGCGGTTAGGCTATTCGGAGATGCGAGGCCGATCAATGAACCTCGACGACGGGCTAAAGCGTCTTAA

Protein sequences of DBSCAN-SWA_4

>NZ_CP053618|6218792:6293539|6238341_6238923_-|WP_006386205.1|DBSCAN-SWA
MDRSLGACLARHPVIATLYGPEQVNAFVGSVAEIGIVANVELRRLAPVISALNRAGKYVIVNIDSCEGLSQDKGGVEYLADIGVASLVSTRVATIQRANRAGMVTMQKVFVTDRSTWPRSVKALEQSDPNLVQIMPAPMLAHMAPQDLKALPPIVASGFVCNQADVAAALRQGAVAVSTSDVALWSVDPRTPR
>NZ_CP053618|6218792:6293539|6284412_6284667_+|WP_020928387.1|DBSCAN-SWA
MTKNDLQAKHIEAMRAVANGADVWAYGTAVDLREVQRAAPELITIGRAMMAPDDGAKQQPYFGAILTDAGREFVGLPRLMAAAA
>NZ_CP053618|6218792:6293539|6266882_6267887_-|WP_020928365.1|capsid|DBSCAN-SWA
MAHIDIFRDNAFSLASLTAALNVQPEGQAVPSTLDSMFDEDGVSTLTVSIERENGKLALVPDSPRGSPGQTTEKDRRDLIPFNTLHLPLRDTIYADEIQGVRAFGTESELEVMQGIVNKRTVKLRSRINATLAYHRLGAVTGKIFDADGQRVLLDLYDRFGYTQKTVNLALGTATTKVRQKVLDAKRQAEDALAGAVQIKGWLGIMGRALYDAFTGHDSVEKAFDRWKDGEFLRADMRKGFIFEDVEWKEYYGKVGAVTFLDPNEGYLVPIVTEDLFQTRFAPANHIDVVNTPGLPFYASQEILQHGMGVDLKVQSNPLTINTRPNAVIRLKAS
>NZ_CP053618|6218792:6293539|6261076_6264052_-|WP_045953224.1|tail|DBSCAN-SWA
MNDKVLGVTLTANEADLLRGFSASGAATAEFAATAEANLGRASAASARMGASAGQMAQAVNASAAGSQAFVQTSERFVQGLERQVQAIGKTRSELLELQAAELGVSARAAPLIAKLREQEVALGSSGRALDRYGNSAAQTAAAMRGVPAQLTDIVVSLQGGQQPMTVLLQQGGQLKDMFGGVVPAAKALGSTLLGLINPYTLAAGAAVAFGIAAYQGSEDASRLNRTIQLTGNYAGVTAEKIRSMAAAAAGENGSRSKAQQAVEALVATGQISADTIQLMSSSMVAFQKASGQAMDEISKDFAKMPEGVTKWAEEHNRSLNFMSLAQWDYIRTLEETGNREGAMQETSRALHDYLGTEAPEKLGVLERAWRDVKGAVDGAWESMKRVGQEQDPLEARIATLRENIALMRQRDAGPAGLNEAGRARVRNAEGALGDALDQKGLADAVAQVKGLNAAANAAAIEAAKSLDAYDKQTNKVRQLTEALEKNARLEAAIRAVNPEDDRISSKAIREREAETRKKFQDKDAVSAGQNSLSGQLAAMQAQARMREEALRAETAALEGQRAAGLLSEEAFIRRRAAAQRAALSDELDIARKQADIAGGKKQIAERERYTGRVQELEAQIARSQQQEATDIEKYQAKIRGALRATQLDIANYSETRALQESRQNNALTLGSNDRALVDAINQAQDRFRRIRDGFTDKMLREGGGGALESDQYLQGIAQIDAAMQAQIERERGYMEERVALQGDWKNGAIRALNDWADASANVMAQSQQVFSSLFQGMSDAVASFVVSGKANFADFAKSVLSDLARIAARQATMGIFTSVVGSLFGAASGAAAGTEAAASQVQASGGDGIGSLIASNGWTANAKGNVYESPSLSAFSNGVFHTPQVFQFAKGAGVFAEAGPEAIMPLRRGPDGRLGVQAIGMAQPSQAAAPVQVNIYMQQDGTSRTEAPQGLEQFGRELGEFVDSRCQVLIAKSYRPGGASWNERYGRKGQ
>NZ_CP053618|6218792:6293539|6284696_6284927_+|WP_020928388.1|DBSCAN-SWA
MEEVTIHEAGALLAATGRIMMRHGVHFDVLVGDCRDDCSDADLLEIMGNAGVPEERARELLRMDLSDVIADLHFGT
>NZ_CP053618|6218792:6293539|6224490_6225054_-|WP_172999574.1|DBSCAN-SWA
MTQPGQEPVSLRAADIVAFWRDAGPQQWFTKDAAFDERFRQHCGPAHMAAAARQLDAWMDEPEGALALMILLDQYPRNAYRGTAHMFATDPLALVFAERAIAAGHDLAVDPVLRQFFYMPFEHAETVAAQNRAVALMEPLGADAVRWAVLHRDIIKRFGRFPHRNAALGRQTTQPEQEFLDAGGFAG
>NZ_CP053618|6218792:6293539|6267967_6268318_-|WP_020928366.1|head|DBSCAN-SWA
MKILHEKARTAEFLLSEGAGEISREKIILAATATGYPSGQVLGQITATKQYAAYNPAGTDGTEKAAAVLYGAADISTDPEPATAIVRLAEVAATSLTGLDAEARADFAPTFLIVRD
>NZ_CP053618|6218792:6293539|6242153_6243692_-|WP_006386208.1|DBSCAN-SWA
MSNNVILAIDAGTSGTRAALVSGDGHVSGQEYLALQVDTPRPGVVEQDADAILERTLQVCRKVIAQARRDGQAIVALALATQRATAVLWDTATGRALVPAMVWQDTRYVDELDRLAPAWNPRLLEQVGRPAGVRSPYLWAARHLRDSPAVAQAWRERRLAFGTVDTWLLWHMSDRRECVTTPTNATSAGAYVLSGHRYYLDWIDALEFPRELLPALRQEADDFGQTRADLLGLAVPIRASAGDQHAGAVGLGCLDRGQAMCVHGTGSFVDLIIGPEAPVNSGRYEGSLTMTARRQDQVSHFAVETFVATTGSALNWVCDKLKWFRNAQEISELAATAQSAGGVTFIPALTGLRVPRMAAGARASLTGISMATTQAEVAYAILEGIAHSVASCIEADEEVSGVQVSELVVGGGLSSSDPLLRIQADLLGIPIRRMQEADRASLRGAAFLAGASGLLWPSLQAARQTAATDAVFQPTLAAEARARRRALWHSRVESELAHAGLYSQDKQEALRT
>NZ_CP053618|6218792:6293539|6287736_6288636_+|WP_020928393.1|DBSCAN-SWA
MWFKNLKIYRLPSPWQLFGDDLEAVLARHAYDGGSNLEMQSLGWIPPREGGGLAHVVGGQILLTLRAGQKLLPPKVVNQVAKARAQEIEEQQGYKPGRKQMKEIKERVTDELLPRAFSVYRDTRAWIDPLNRWLVIDAAASSKADEVIGLLSKCVDPFPLENLYVAQSPASAMTGWLAEDEAPNNFTIDQDSELRASGASRAAIRYLRHSIDADDARRHIQSGKQCTRLALTWADRISFVLTEELDVKRLVALDVLKEGNDTIAANDDEKFDSDMTLMTGELAKLLAELVDALGGEKRI
>NZ_CP053618|6218792:6293539|6246866_6247142_-|WP_108914266.1|DBSCAN-SWA
MLSIQMLSRGGLLLLVALLSGCSSSSINPWSSPAAPGSGSDSSRVSLECRVSRSSCIYEGKYETGERDYAEDEAKRLNRAEMERLRRAFGG
>NZ_CP053618|6218792:6293539|6238924_6240481_-|WP_024069447.1|DBSCAN-SWA
MISKEAIKRGYNRGNYVVGAHTPPAYAAGLTQAGTEPGLQRDPVSVSAAQVEALRAAADEVLTTTADAVAWTRDWWAGSMMTETAGRPATPHAVIVKVSTVEQVQAVMRIAHAAAIPVTVSAGRSNVTGAALPLRGGIVLDVCQLNRFIGIDRESQIVEVEAGMFGDVFEQAIQREHGLTMGHWPSSFGISTVGGWVACRGAGQLSTRYGKIEDMVFGMDVVLADGSLITVGGYSRAALGPDLLQLFIGSEGTLGVVVRVRLKLHRLPDYGRAIAYGFETFAAGLDACRQIMQRGANPAALRLYDALESGVQFNRPDLNVLLVADEGPRPIVDAVMGISEEVCRESGVALDGNEVFERWLDTRYLTGKSAEGFKRSPGFVADTLEMAGRWSDLSAIYDEVVAAVNAVPGTLAGSAHQSHAYVDGACLYFSLRGEVAVDERAQWYRRAWDAANAVLIKYNAALSHHHGVGLLRSPYMRESLGPAFAVLHAVKQALDPHNILNPGKLGLTDEGPYDQGRR
>NZ_CP053618|6218792:6293539|6279700_6280144_-|WP_020928379.1|DBSCAN-SWA
MNITTAADLTVHEFKGGSESLGPLVGITPAVLRNKVNPNNTTHHLTLAEAVRICRMTGDFRILAAWAHEAGFLLVKAPESCGDSDMSVLEQVAALMVANGQLGKEVYDALADGGVDRAEVERVSSAARVVMQAAAEVARRLKGMAEQ
>NZ_CP053618|6218792:6293539|6291621_6292179_+|WP_080945043.1|DBSCAN-SWA
MAAALASAPVAGEVQPVAVTDHQGDVHWRHGRKAGIALYAAPQASADAFDFVAHLARQAEFSARTFGPGARVAGVCDHIRKELIDVETSGGDLKEWVDVIILGLDGAWRSGATPQEIIAAIVAKQAKNEARTWPDWRTVDPNKAIEHQRTASPYTCPSGDGSLRHPCAAHPAKASGNGGEEWSDS
>NZ_CP053618|6218792:6293539|6248850_6249108_-|WP_045953215.1|DBSCAN-SWA
MDSEELLAMMISTPAPAPNLDDWDSVLVIYARHLERLAPKLNERDLGALVASGAMFYRTLRQAEAARLQALDRWSGPAGRGPGAD
>NZ_CP053618|6218792:6293539|6271233_6273228_-|WP_080945041.1|terminase|DBSCAN-SWA
MTLREWAERNFYLSAESSYVEQNWEAWPFQRAILACIGSDDLHEVDVIKSARVGYTKIVLAAVGYFAEHRRRNQALWQPTDSARDEFVKTELEPMLRDVEVMHPIFPTRLARHKDNTLLVKKFIGSALHLRGGRAGDNYRRLSVSVAILDEFSSFDSNIDGEGDPGQLAAKRLEGATFPKMVIGSTPKLKETCLMEKRAAGADARYDYHIRCPHCDEHHALTWGGKDEPHGFKWLNDDPETVRHLCPHCGTLIAQGEYLAAAEDGFWYGSDGTTIDRDGVFRDAAGDVIPAHKRVAFHVWTAYSPMVSWAKIVREFLDAYAKAEQGDDEPLKTFWNTTLGQAWEGEIEKIEADELKRRAEIEAYRLPGQAENVVPLGCTLLLAGCDTQGNRVEVAVWGFGRGCEMWTVDHQIFHGNPAEDEVWNSVAEYLFERRFQHEGGQQMSIYATAIDSGGHYSNAVYDFARRNKARRVYAVRGRPFGEKAIKDGAGQVDIDWRGKRVKKGVILWHVGTNRAKDLLHSRLAIESPGPGYVHLSADLSDEWFRQFSGEVRVARKTATGVRTLWTAIRKRVETWDCAVYALWVAEHLGLTRKTEAWWDAMAAKLDALPPPADSVEADDAPPPAARGRRPSPAVPAEAAPAKPRAPPRPARRRSSSSSYLKARR
>NZ_CP053618|6218792:6293539|6280708_6280984_-|WP_080944995.1|DBSCAN-SWA
MEPDQYPHRPALLAACKQLGTKAALARAVGVLPQQVGNWLNRDKEIDPVYCARIETATGRRVLRQALRPHDWQTVWPELAREVSTQGGVHA
>NZ_CP053618|6218792:6293539|6273305_6273803_-|WP_006387630.1|terminase|DBSCAN-SWA
MIDLDKKTTQARFAQLVGVTQPVISGLLMRGVLTSGDTLGNWLLAYCGNLRDAAAGRNRDPESKGLDPAEEKARLNAAQADKVEMENAERRGELAPVSVLEEVLVRAGTKVAATFDAIPGILKRRLPNLTDADLTIVRRELAKARNAVAALSLEDIESEDDNEGE
>NZ_CP053618|6218792:6293539|6233775_6234084_-|WP_006386200.1|DBSCAN-SWA
MSFYAIVAVRKEAVTGHVAYVRWGLAERGVPGWVSEPVTAAASEVIEAIKAGADVETVVSVDGLSVASRPVRVLTDEDGREHLASVPAPSSTLHTVFDLPEF
>NZ_CP053618|6218792:6293539|6290840_6291011_+|WP_158324534.1|DBSCAN-SWA
MKPATAAAVAAATSIASYATGYASAHTDHSLGTPFFIGLMLAAVFAGLAFAAVEKD
>NZ_CP053618|6218792:6293539|6246252_6246765_+|WP_054447772.1|DBSCAN-SWA
MLLLSVCVLAASSLGVLTWRIVRRPEGKTRGDIARAGAAGAALFAALGPPVGTLVFALFLATAAMSLESLFTSVFLVPWSYLYGGVPALLCGLVTGACRPAVVTWRSYCWPGLLGGLYAFVFLAGFAVRENTLSELGFPLFLGGVPGLISGVVCARVFYGKPQATAPAAA
>NZ_CP053618|6218792:6293539|6243706_6245164_-|WP_006386209.1|DBSCAN-SWA
MQSLPVKLRGIDDVIAYIDSCPGIVGRAGLIWWLALGGLFLDAFANSALSAGLGPMTRDLGLSAGQVALMTSFASWVAIAFNPIGGWMADRWGRMRPLITAKLLALIGALLVVFAPSFDVILAGRFFVGAAYGIDFAIAMAVLAEFTPVRLKSRLNTWQGMWYTAVCSNLLLALLFHSWEVGDAIWRYSVAATAVFALAILVLQLRYMVESPIWLARKERVDEAAVAMTRIYGQPFTAAPPHERVPVVNQARRGLANVLLIFRGVYLPRTILAATVQIGQSIQYFAVGWYLPLISAALFGKDFVYATVGALVFNIFGIFGGFMSPYIGRKLGLRRASAFGFAAVFLMLLILGTFHGKMPLWLAVAVPSLFILFHSGGPGANGKSLSSLSFRGELRAGANGVIGALGSIGAAVGLLVFPLFRESYGLEKTFLILSAVPLAASIICFAIKWDPTRSGINPDNEAGAPQFKGDENLPALDPALGKTAR
>NZ_CP053618|6218792:6293539|6269483_6270983_-|WP_045953227.1|portal|DBSCAN-SWA
MSYAKHRRSGLLVPRRLNAQMSSSYESGSATGSRAKNWNPSAAGPNSAATQGLPLQRRRARDAVRNDPWASTAERKWDSNAVGTGIQPYPQHPDKSVRRLLKELWADWCVEADADGRLDFYGMQSLADRSIFTAGEIFCRFRRRRPSDGLVVPLQLQLIEGDQVPVERTYPLPNGGEVVNGIEFDAIGRRTAVHMWRRHPGEFGRSSPAQEIVSVPADQVIHAYQMQRPGQVRGVPALATVLLRLKSIDNLDDAVMYRQEVSNLFAGFITRPDPDEDPTNPLTGGQEDYVEDDDGIPLVSMEPGTMQELAPGEQVTFSTPPGADNNYDSFMRHQLMAAFASVGIPYELATGDLRNISDRALRVLVNEFHRLIEQYQWHCLIHQFCRPVWAAWIDALALAGTIPMPDYHRRRREWLRVLWVPQGWPYFHPVQDIEAKKMQVRSGFTSRSAVILAQGDDPDQVAADIEADNLAADAARAVFDSDPRRSTSAGKVLSPADVE
>NZ_CP053618|6218792:6293539|6222329_6223085_-|WP_006386184.1|DBSCAN-SWA
MKIRYTVAALAVALAPYSASHALDIGGLVGAGSKVVQAATLSDAEIKTLSDKACAQSDSQEKIAAPGSKYDVRLQKIAKQLGGTVNGQKANYKVYITKDVNAWAMANGCIRVYSGLMDMMTDDEVLGVVGHEIGHVALGHSKKAMQTAYTVSAARDAAGAAGGATVAALNSSQLGDLTEKFINAQFSQSQESAADDYSFDQLQAKKLNTRGLVTAFQKLAELDGGKSDMMSSHPSSAKRAQHIEDRIAKAK
>NZ_CP053618|6218792:6293539|6227164_6227437_-|WP_173011185.1|DBSCAN-SWA
MHYEYLFWSMAAMVAAALVGGSLCGRLRTPGRVLAGVVVWAAAVCAVVVVVSRSAGFGDQAAMLAVAAFMFSLVIGAAAALLTRRILRRH
>NZ_CP053618|6218792:6293539|6289645_6289984_+|WP_173011188.1|DBSCAN-SWA
MNAPAPKTSPDTALGNLMAAALDVPAAPEQPAVPDDTLARTGNTARDQEMYAAGIRTGEENAKHNAAIRAGASWQPIESAPKTGCTLLLGYWNSHGKWRTVRGQWISAEYIA
>NZ_CP053618|6218792:6293539|6232848_6233376_+|WP_006386198.1|DBSCAN-SWA
MKLLRHYALAALLCGAVLLPAAAPAQPPAPDVTQALVGKWRHQTMLRTVDGKAQPPQPSGGAGVVEFRGDGTWSMQGPDMVSSGTYRWLDAKRIEQTLEQSTSKHELGVASIRYVKIQGDHLSLTRVQDRREMDKLMPPPGPNVRRPDQLIVTNVFTRLPAEPNPSAPAGGAGHR
>NZ_CP053618|6218792:6293539|6285323_6285647_-|WP_144415882.1|DBSCAN-SWA
MRLLRQLRLELAQAADQLLLADQVLDAVAAPAGLDGGNEDFDGRLALRALQLVGFAGFDDDYINLRLKWRRPCASVLPAHHLAGVFQDVEQGRCEFADGINGGIEHG
>NZ_CP053618|6218792:6293539|6284186_6284390_+|WP_045953236.1|DBSCAN-SWA
MATVEFHDEIGGAYLDEHPAGIFGSRCHYDRRYWHAWASSPDPQKRDCIPGVMDDFGTLVPVPSPSY
>NZ_CP053618|6218792:6293539|6286217_6286874_+|WP_020928390.1|DBSCAN-SWA
MQHTPPPGAFPQYRIIGLVGRAGAGKDTCADILVKTRGFARLAFADALRDEVVAAFSVDVTPFADRVLKERPTPALQIRRSADEEFIARAKALGYDLWAQRSPREIMRLWGTEYRRQVTADNYWLERANDRVNALLASGIRRICFTDVRYANEAAYVTESLRGDLWRIRRRSADSRHATHSSESDLERIQCKEVIHNELGLQELALEAQAALVRHVLE
>NZ_CP053618|6218792:6293539|6223347_6223893_+|WP_006386185.1|DBSCAN-SWA
MTPNTPPRLGLLPSLIFSSRWLQLPLYLGLIVAQGVYVMLFLKELWHLLTHATSFGEMEIMLLVLGLIDVVMISNLLVMVIVGGYETFVSRLRLQGHPDQPEWLSHVNASVLKVKLAMAIIGISSIHLLRTFIEAGTLGTPNARFSEAGVMWQTIIHALFILSALGIALVDKLSTPSHPKH
>NZ_CP053618|6218792:6293539|6282822_6283185_+|WP_045953234.1|DBSCAN-SWA
MSEQFKDYVTGGAFHLSLSKRQVEMLGHLYQFGSTWGYLSSCNALIAKGLAERIEEEEPGGEGTCLVGSGKVVLSEAGKALMPLLILAGLYQPWEMPQPVEIPPVNIRIKRRDESEVLER
>NZ_CP053618|6218792:6293539|6253361_6253652_-|WP_045953218.1|DBSCAN-SWA
MAVPLQIWDMYGRELFNFNTRVARQLGSFSTGTSDGSTYIDAINGPDGWIAVQAIGDYGFARNNAMIARVGGSISWRFIPGHPSPRVGVKVIYGVK
>NZ_CP053618|6218792:6293539|6252696_6253362_-|WP_045953217.1|DBSCAN-SWA
MADAAVVLYNEAGDLIVDSRNVNMFLRYSGVTGPDRYNNVTLGCLDPVLFFRPVSGFGGVDSMDMGGGTYLFRFRGQCEYYVFDRPWVTGGPIDIWDQSGRHIFMSTARPMNVVQTFDIPTYFDAYRTAYQDGWTFSGLPSSKYAYNLSYTRQGYNCLPAMGGGWETLTCDERITATANGLYANFPEYGTRYLGWAPIYSNTFLSYGGACPVSVIDVTGWL
>NZ_CP053618|6218792:6293539|6232143_6232725_+|WP_006386197.1|DBSCAN-SWA
MSRSRAEMIEETRGKLLATARESFRRAGYAGTSMDDLTAAAGLTRGALYHHFGDKQGLLAAVAAQIDAEMEARLQAISRDAPDAWTALRERCRAYLEMAADPEIRRIVLQDARAVLGHAGAAAQEQCTASLGELLQDLMDQGVIVAAPPRALARMLHGGLAESAFWIAEDDGPARLAQALQALDLLLQGMRRR
>NZ_CP053618|6218792:6293539|6225278_6225482_-|WP_006220190.1|DBSCAN-SWA
METGVVKWFNSEKGYGFITPEAGGKDLFAHFSEIQGSGFKSLEENQRVSFVTANGPKGPQATKIQVL
>NZ_CP053618|6218792:6293539|6253653_6256821_-|WP_020928355.1|DBSCAN-SWA
MKQRVRMKRQAPKGAFFYGRKDRVIVGHKGGKGGGGGRGPTEAPDSLHSIAYARVIDLLSEGEIYGPTHGLGGALRDVYLNGTPVANEDGSLNFSGVSVDFRTGTQWQDPLPGFPASENTIGIGVELKATQPWVRLFTNRQLSAVRVTLAVEGLSRADTKNGDINGYRVEYAIDVSRDGAAYQQVLASAFDGKTTQRYARSHRIELPAGALQGWNVRVRRLTTNANSSTISDRTVVDAVTEVIDAKLRYPMSAVVGIKVDASQFQSVPTRAYDLKGRIIRVPSNYDPETRTYTGVWDGTFKLAWTDNPAWVFFDLVSNDRYGLGERVPAGWLDKWGLYQIGRYCDELVDDGFGGKEPRFACNVFLQTTADATRVLQDMASVFRGMAYWANSSVFAVADMPGDPVYTFSSANVIGGKFNYTGSALNTRYTVALVSWNDLSDMGRQKVEYVENREGIARYGIKQLEVTAFGCTSRGQANRVGKWLLLTSQLETRGVTFTVGLDHCQIRPGSIIRVADQHLAGRRIGGRIREATASRIVVDAELGIRPGDRLTVNLPSGKSETRVVSSAMGEPLTLDSGVYSYDSTALTWDLIGLPGTAMHIDVKTPFSEVPEAECVWTLESEALSAQTFRVLRIERKDGLQAEISAIQHEPGKFNNVDFGTRLDRPPISVVPPGVQSPPTEPKISAYYIVSQGIANHTAVFEWKAADSAVAYEVQWRRDNSDWINLPRTGYTRVEVPNIYAGGYTFRVRALNALDVASIWSTSTLTQLDGILGPPPRVTSMATTSLAFGVRLDWGLPAGPSIIGRTELFYSRTPSFDDATRLGDFAYPQNTHTLMGLAAGVEFWFWARLVDKNGVAGEIYPSGAGVHGKASADADLILDYIAGQIKETHLYQALREKIDSAGEAAVEVAALTSALAAMWTVKTQMTVDGKPYMAGIGVGVENDKGVVTSQVLLSAQRVAVLDESSGSLKTPFVVQGGQVFINQAFIGRASIGSAQIADVLRSDAVNPQGLPVFSLNMRSGVMSFNGTVSDGSRTEINNNGMRYYYPNGVLGARFGGG
>NZ_CP053618|6218792:6293539|6290221_6290620_+|WP_173011189.1|DBSCAN-SWA
MQEFKEECECCEGRGFVFAFQDIPGIEEYVKACRTAPAAGDALDAARWRAYAKLFPEVSASFLATHAVDGDDPLPTIKGASITGGYVVVTPAGWDADNATKLRDAILRLFPVNPVHTPRPSDELAAQRKGDA
>NZ_CP053618|6218792:6293539|6234150_6235008_-|WP_006386201.1|DBSCAN-SWA
MTAPEVIISPSITCANDQPFVLFGGINVLESKDLALRACEEYQRVTTRLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFEAVKQNFGVPVITDVHEPWQAAPVAEVADILQLPAFLARQTDLVVALAKTGRVVNIKKPQFLSPTQMLNIVEKFTEAGNQQIILCDRGTSFGYDNLVVDMLGFGVMKKVTGNRPVIFDVTHALQQRSALDAASGGRREQVAELARAGMGVGLAGLFLEAHPDPRNAKCDGPSALPLDKLEPFLTQLKQLDDLVKSFEPIDIEP
>NZ_CP053618|6218792:6293539|6249861_6250899_+|WP_045953216.1|DBSCAN-SWA
MSGLDTVLTNHQRVVREGYRKEVGQGFKSYAISNLRGGVGKSSIAFNLAYEMSRQEAVLFSDLCPQCNFTETLLGDFRPKVNIYDAMKPMILGSAFGDIPTDLTYNVARYCDDFKGGKGAYVIGGSPELFAFPSLLYQQLNTAYSQKNTVAVERLLHGLRNVLEKESAEARCSKILLDTSPFYAGGTHLAWCAVDALIVPVRVDEHSLESLELLLKMLSDPARDYQMWNERAGGLSVPKIAAVVMTMVGSKSQVEATPDSASRMYIERAIGIAEKYSPLFGHSDPSDAFVITDDFHSAGRISGARRIPITELRVKTFHTVEGRRLQVNASATRYQKQLRYLASMI
>NZ_CP053618|6218792:6293539|6283264_6283555_+|WP_020928384.1|DBSCAN-SWA
MATPQRIAPPSLNRGVFGWDSCRLADAYSTQELTDAITWISHAPCCANPETGSIWLLNKKARRISEQLAWAVRHQMEEKRRAEQYPLGYMQGRGAA
>NZ_CP053618|6218792:6293539|6282648_6282813_+|WP_020928382.1|DBSCAN-SWA
MSEMANMLVMFVIGFGVGVIYGRMKGMSVEDELNMKINDLAQQVRILKKRLDSE
>NZ_CP053618|6218792:6293539|6278269_6279010_-|WP_020928376.1|DBSCAN-SWA
MNALIIATTAIRQDEEGRFSLNDLHRAAGGERRHQPSDWVRLQQTQDLIAELGDMIPGIPGIFSRQGLGTYVAKELVYAYAMWISAAFHLRVIRAYDALQSPAVPRDFAAALRLAADQQDEIYRQRQQLLEQQPKVEFAEAVRSTVDGISIRDMAKLLGTGQNRFFRQLRADRVLLEDNKPYQEYLDRGYFRLIEMPWRADDGQVHVSFKTLVTGKGQVWLQRRYAPPAPAQAQACLPSGLAHAAA
>NZ_CP053618|6218792:6293539|6230353_6230752_-|WP_020928335.1|DBSCAN-SWA
MSRTVVNPDTVFNTVQYGFSQAVIVTGQRRMLLSGQVGVDAQERTVSPGLREQADAAIDNIERVLAAAGGTLAQVIMLRIYICETAREDQESIAQVLRDRFPNDPPPSSWIIVSGLSLPEWLVEIEAEAMLD
>NZ_CP053618|6218792:6293539|6288651_6289446_+|WP_020928394.1|DBSCAN-SWA
MAKKSKDVYGAEGQSNLLTFDPDKLVLVTDESSPLYDPRVHLPVDEAMARNIDFQGVIEPIGISKNPETGETEVVFGRQRVKAARLANQWRHDRGVPPRLIPGVVWHGERKDALDAIVGENEARTADTPLGRAEKMRRHLALGKGEDQIAVIYNCSVATVRDTLALLDSPKVVQNAVEAGQITLTHAKALAKLPVAEQRTKVAELVQAGQGVKAHERSRKQAAVMGERPRVKSRKQIQAALETSQGDYAAALRWVLGEEGGAAA
>NZ_CP053618|6218792:6293539|6287355_6287715_+|WP_020928392.1|DBSCAN-SWA
MSAFCVFGMTETLARKAAERAWQKHLESLTKEARACLTPADETEWIKVKTEYHLSKGKTIQLSAPFDAPQFAQDFIKLARATGRTSRLEVMRRAPLLDKNGAPRISKATKRQMIGWVPQ
>NZ_CP053618|6218792:6293539|6276353_6276557_-|WP_020928373.1|DBSCAN-SWA
MSRDLQRWEMRNPVEVLISRETAAVRRSCAGCVHAKVVESPFGESVTRCLKGRPYGRKCKRFEVINV
>NZ_CP053618|6218792:6293539|6252158_6252602_-|WP_020928354.1|DBSCAN-SWA
MEPGSTGLGGWAAVKIALAFGLPAALAAILGMVIMPPRSPQEFIKRTVCTVSCSFVFGPILAIAVLSWRPSLMETAHWVAARSGGGEEKLLALFYVLGPCMLLAGLPAWWVLGAYMRWMASMRQKGLLEWFAEARAKLLGLRSGGES
>NZ_CP053618|6218792:6293539|6289442_6289649_+|WP_045953237.1|DBSCAN-SWA
MIKLTDSNGAALYLAPAAIASIKEAGPSSAWHGIRSYVRTFDGKAYEVQQDANEINAAVQAAEKRSEA
>NZ_CP053618|6218792:6293539|6223991_6224198_-|WP_006225311.1|DBSCAN-SWA
MATGIVKWFNAEKGYGFIMPDDGSKDLFAHYSEIRSEGYKSLQENQRVTFEVGTGPKGPSAKNIKVAA
>NZ_CP053618|6218792:6293539|6264462_6264882_-|WP_020928361.1|DBSCAN-SWA
MPFVVSKRALAACDIKVAVHGENGAPVEIDFIAQYKRSPLDQINALHDAMTNAYRERLGQPLLPVGKGQKAAEKWEYASDVEFIKDRMTGWLGVRDGQGDAVPFSAKALDQVLKDWPELVAPLFQGFWRAHQQVREKNS
>NZ_CP053618|6218792:6293539|6264085_6264397_-|WP_006387642.1|DBSCAN-SWA
MLAALTLAGAPADVLDAAGARAADEPFEVFEENWETVRAFLELETCWTWVAPAMGPPLRTGISATEIRATLEVLMPPGADLREAFLDIRAMERAALEVFLGQA
>NZ_CP053618|6218792:6293539|6236227_6237445_+|WP_020928340.1|DBSCAN-SWA
MGLLDSLFRRKPTQDQFARLFIDAVRQRGYTGTLDYKADEFRLLHGEGSYFNLHNAYNAYCEARSGQRQGALQGYVSTLLTSDQARPASLAEARPLLRPVIRARAMIEAIRMHHLRTDGNDTDFRPALRPFGDDCVVLLALDHPESIATLTNGPDADWGLSFEQSLAIAIDNLRDSADHFVEVAPGVHGGAWEDGYDISRALLPDMLERVAVRGRPVFMMPTRDLLLVSGDNDDAGLLKMMELSQQVVAHGRPVSPYMYHYGETGVERYLPRQERIIHLQAHLARVLAQGDYDAQKEALDRLHEERGINVFVATYNLFMQNDDSATSFSLATWTRGVDTSLPKVDRLALVRPEANDDIGEVRVVHWEQAAPVLAPLLEPEDLYPARYRTRGFPSDAQLAQLPEAD
>NZ_CP053618|6218792:6293539|6268345_6269455_-|WP_045953226.1|protease|DBSCAN-SWA
MAKKLWYTITAKAQAEKPVVEIRIYDEISFWGTTAEAFVAELDAAAAGGADIVVSLNSPGGDVFDALAIYNALRRYAGRVTTRVDGFAASAASLIAMAGDQLIMPENAQLMIHNAWTIAGGTAEDLRSTADMMDRVRDGVVAAYARKSGQDADKIVEMMDATTWMSALEAQALGFCDLIEDPVRLQMSSDLAAEVLRKHKNLPAEVSAMLDALEAESPRDPAPPPATTADAPPPLAPAAEPQANAAQATALVGHVYAACRTAGVAHLAEGVLLSCGLASKEGADERIVQAAEIAGVCLAAKMADKAPEFVAAGLSVDQTRARLFDALAAASEQTVDNRQRPDANPASAAPALSITNFYEARAAARRRAS
>NZ_CP053618|6218792:6293539|6229253_6230171_+|WP_173011187.1|DBSCAN-SWA
MITTDDLRFFLSLAATSSLAQAARALDVTPPAVTQRLHALEKRLGVRLVNRSGRGTALTDEGRLLALRAGQICGELNELADELAGRRGVVACHLRVVAPLGFGQRYVAGLVAEFRQHSDNVTASLVLSDGPPRLASDDWDVMVHIGELRDSTLVAYPLAPNRRILCASPAYLARHGAPAKPEDLRDHDCIALRENEEDVTLWRFKRGRGPVVGVRIAPVLSSNTGATAVAWALAGHGIVARSEWDVAEHVKRRALVPLLPGWSLPEANVVALVKSRQDLPARTAGFLAHLREAFAATPWRDKGQA
>NZ_CP053618|6218792:6293539|6280394_6280616_+|WP_020928380.1|DBSCAN-SWA
MALKFVSITQPTEDSEEVGVSFQLDSEYTGKPPYFIGQAQVSIPLSEALEMTLAEIIGSARAQLKVRLIDCAK
>NZ_CP053618|6218792:6293539|6233446_6233752_+|WP_020928338.1|DBSCAN-SWA
MKPKIRVLRVQPSSMSARFAFLAIALRWSLGATPRPARLRIGPHDLAPVGSEAAFWMFALRHALSAQSVLVTRGDHWDVAASVDGDVIRAFGRKFALRQCL
>NZ_CP053618|6218792:6293539|6237488_6238199_-|WP_024069446.1|DBSCAN-SWA
MYPLSKRCGAEFFGTFWLVLGGCGAAVLAAGFPQLGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTVGLVAGGRFPAREILPYVVAQVLGAIAAAAVLAVIANGQQGFDLQASRFAANGFDAYSPGKYSMAAALVTEVVMTAGFLFVILGATSKRAPAGFAAIPIGLALTLIHLVSIPVTNTSVNPARSTGPALFVGGWALEQLWLFWVAPIVGAIIGAIAYRLVSQSEAQP
>NZ_CP053618|6218792:6293539|6270979_6271186_-|WP_020928369.1|DBSCAN-SWA
MAYTQADLEKLDRAIAGSQLEVQYDGKRVRFRSIDELMRARAHVSAEINKGKRRPRQFRLRSAGKGIR
>NZ_CP053618|6218792:6293539|6273799_6274585_-|WP_045953229.1|DBSCAN-SWA
MLKFTSKLRDGVDYYAAMRRQLPYATSVALNRTADAVRQALVQQTQQVFDRPTPYTLNALRVVRASKGNLVATIAYRDGAGKGTSADRYLAPQVFGGGRRLKRSERALQRAGLPAGMFTVPAAAAELDAYGNMSRGQVVRLLSYFEAFGEQGYRANATARSRARTANVGTSREGYRRINGVQYFISRGKGSMSGHRRQVLPAGIWRKTGTHGADVAPVLLAVEQPQYTPRLPLYETAAAVYGERFDVEYSTALDAALATAR
>NZ_CP053618|6218792:6293539|6279293_6279704_-|WP_045953232.1|DBSCAN-SWA
MKGKPANVVERAFHDLLCSVVGCAACRFGHHVVTHYVSVHHMRGRTRPGVQYFVLPLCAGHHQRGTGAPWMKAVHEDRAAFIHRYGTQEHLLRQCVLFLLARGHDVPRGGLDAAGIDTDVAALAIAMHKEGRKVAA
>NZ_CP053618|6218792:6293539|6283999_6284185_+|WP_020928386.1|DBSCAN-SWA
METAEDLSYALAKQLASAHTISTSYGDIPLDDEMRAAVDNAVRPILKRRLNARLADTAAKE
>NZ_CP053618|6218792:6293539|6281091_6281823_+|WP_052719205.1|DBSCAN-SWA
MAMGKNIRFLRLAKGLTHDALGALASTSGQTVDQLEKRDSKRSNYAGGIAHAFGLSVEELQNAALESVDDAMRLLGDVARRNREVSAPLDTHRHLVSEPQPEYVGRAVSGRLIPVVGMAQLGENGYYEEVAYPDCQVDGFILHASSDPDAYVLRVRGDSMKPAIRNGWYVVVEPNSPAAPGEYVALQLADGRKMVKELIIQRRDGDIEVLSVNGEVRMSLHAGQVERMHAIGAIVPPSKHRTH
>NZ_CP053618|6218792:6293539|6258940_6259480_-|WP_052719203.1|DBSCAN-SWA
MRLLVDEEGMVVNVILAGDSFDPGPGFRVVPPNPAEAAVGWRMDQQGVAWPPLLPSEDLPSIEEVRRRKHSEINDAFESAASALTVGYPETERLTWTVQLQEVLAWDANSQAATPYLDGLAIERGISAIDMRTKTLEQVRQFLAASQVLVGKRQRLRDAVNAVQPGPNAINELAAIAWG
>NZ_CP053618|6218792:6293539|6256817_6257429_-|WP_045953220.1|tail|DBSCAN-SWA
MIETMRTVRLYGRLGAEFGRVHRLAVNNTAEAVRALCVLVPGFEAAMAASAGSGVSYACFVGRRNIPEGELSHPVGDDDIRIAPVPRGAKRGGLFQTVLGVALIAVATFASSGGTLAAAFAAKGWVGATAMIGASLAFGGVVQMLSPQQRALSTRDRPENGASYNFNGPVNTTAQGNPVPILYGRMIVGSATISAGIFSEDQA
>NZ_CP053618|6218792:6293539|6249383_6249611_+|WP_045953594.1|DBSCAN-SWA
MYSMLHKGLNRHVPRMTMDALAKFGATVPSAIPDLLEPQLLTFASDRGMMVCGFEEIAGVRYYQGWWMQWIAERA
>NZ_CP053618|6218792:6293539|6245416_6245776_+|WP_020928345.1|DBSCAN-SWA
MLSPALVLGASTPDYMGQYDRCLRDAGVTNNGTVGACAEGVSAAAKREINTLYARVQARLATDYPDDAAKLEQTQKAWLAYRNGHCALAGAHVGSPMYEYCPMLLNINRADELRELAGD
>NZ_CP053618|6218792:6293539|6225851_6226172_-|WP_006386188.1|DBSCAN-SWA
MEILSRHVADVAGGVELHTTLDGESISAYVVTGMDDLEAIADLVPREKVEAGADIHAAGVDNVDNAQDQIDQVLENMNPGDVAVFLCSGPEAFNAALDLLGLPIEE
>NZ_CP053618|6218792:6293539|6220192_6220846_-|WP_006386182.1|DBSCAN-SWA
MQRFTDFYAAMNGGSSVTPTGLGYIPMVIEQSGRGERAYDIYSRLLRERLIFLVGPVNDATANLVVAQLLFLESENPDKDISLYINSPGGSVYAGMAIYDTMQFVKPDVSTLCTGLAASMGAFLLAAGKKGKRFTLPNSRIMIHQPSGGAQGQASDIQIQAREILDLRERLNRILADNTGQSIDRIALDTERDNFMSAEDAVSYGLVDKVMTSRSEG
>NZ_CP053618|6218792:6293539|6220850_6222161_-|WP_006386183.1|DBSCAN-SWA
MQPVVETLSGLERRVDLAVSVADVEKEVQAQLKRVARTAKVPGFRPGKAPLAMLERSHGPGIRYDVINSQVGRAFEQAVDGAKLRVAGAPNLEPKTEGVGEDTLAFTATFEVYPEVAVPDLSALAVTRYETAVTDAEVQQTLDVLRKQRATFEAREGRASQDGDRVTLDFAGTIDGVPFDGGKAEDFPFVLGQGRMLPEFEEAARGLKAGESKVFPLKFPDDYQGKEVAGKTAEFTITVKEVAEGVLPELNAEFAKSLGQAEGDIEKLKADIRSNIEREVKVRSQGRTKASVMDALVEAGKFDVPKALVDNDVQSRIAAAREELKQRGVPNAESVPIPAEAFSTESERRVRLGLLVSELVKQAQLQAKPEQVRARIEEFAENYEQPAQVVSYYLADRQRRAEIEAIVLEDNVVAHVLEKAKVTDEKVPFDQLMGMA
>NZ_CP053618|6218792:6293539|6251663_6252155_-|WP_020928353.1|DBSCAN-SWA
MDLKKIIDTGISPALALLPAGMDTQAVRVMLLAIGLQESRFTHRQQIGGPARGFWQFEKGTRASRGGVWGVFLHQASKDRLAALCKARSVACDPDAIYAALEYDDVLAAGVARLLLWTDPRALPAVGDVDAGWSLYLRTWRPGKPHPQTWPALYAQAMAVVEV
>NZ_CP053618|6218792:6293539|6286876_6287332_+|WP_020928391.1|DBSCAN-SWA
MPSVNKVILVGNLGRNPDIRYSPDGAAICSMSIATTSTWKDRASGERREETEWHRVVMYNRLAEIAGEYLRKGRSVYIEGRLKTRKWQDKDTGGDRYSTEIIADQLQMLGGRDGQADGGHAADAPDGSDGQRRHRPAAAPSNDGTDPDIPF
>NZ_CP053618|6218792:6293539|6235244_6236204_+|WP_020928339.1|DBSCAN-SWA
MDTDTLSRRLEFLRQAEKLKDVLRSARSSGGRQESTAEHTWRLCLMAMMLEEDLADLDFTRILRLCVIHDLGEAIHGDIPATQQSPGAGKGAQERLDLLQLASPLDAPARDRLLALWDDYENAASPEARAVKAMDKLETLLQHNQGANAPDFDYAFNLDYGRKHTDALPLFREIRRLLDADTEARIRQQAAERAARPAPSPADVVQRQLDAYNARDIDAFMRAWAQDCEYYAFPDTLLARGSAQVRERHLERFKEPDLHGRLVHRMVNGDMVVDQEVVTRNFADGRGEVDVVAIYEVRDGQIAKAWFRLGAPRLHGGPA
>NZ_CP053618|6218792:6293539|6251394_6251661_-|WP_020928352.1|DBSCAN-SWA
MPAFMQRIRGYVVAALAAVAAVVLVYLRGRRAGRADERQERNDRINEQAAKARQEVRNVEDEVARMDDDAVSDRLKSDWVRRPGQGGR
>NZ_CP053618|6218792:6293539|6226783_6227071_+|WP_006386190.1|DBSCAN-SWA
MQRDFDLVVTILGALRDAPGPNLSTHDIKEAALAHEQGLQLVAHHLDLLADAGLVKQVSETAATAGDTRWRITWKGYDALEQDEEDDDEDFDAEE
>NZ_CP053618|6218792:6293539|6266155_6266578_-|WP_006387638.1|DBSCAN-SWA
MTSLAQRYVEDLRLALAGASEGFPAAVENSPMRAISREDPKVVSVQLGAESIQELLSPRVTRVREIHLIVHTCGDDHLQLAEEVFEAAQPIVMGYSGPNMVSIVEFGTDEPKYANGDLRRQVVTKRYRITYQTDEHSLGA
>NZ_CP053618|6218792:6293539|6258208_6258937_-|WP_045953222.1|tail|DBSCAN-SWA
MRIYADVQKLEVGELVELYELDATPIGGALQRFHGYTQIGPILWQGNRYEPWAITAAGFEQVGEGQQPTPTLTVGNIGTGADGEPVVGVISSLCIHLNDLVGAWVRVRRTLGRYLDAANFPEGNPTANPAEELPAEVWIVQQKTVETAELVEFTLSSALDFDGQQLPGRQIIATVCGWLRKGGYRGPYCGYTGSRMFDLAGNPVTDPARDRCSGLMSDCKKRFGEYEVINFGGFPSSDQIRG
>NZ_CP053618|6218792:6293539|6290619_6290844_+|WP_045953238.1|DBSCAN-SWA
MVDIDSLRVITRQRWGRVTAFRLGQIAAEYLGSVAVDANPYRPEQHSHRNYLEGISFHQAKAAQQSGQGAGSQS
>NZ_CP053618|6218792:6293539|6279006_6279297_-|WP_020928377.1|DBSCAN-SWA
MNVHGYEVPETALDAAREAMASGDEFDTRAISKVIGRHFPFPKGQMSREGYLTVCLDAAHRLVRESRSDLEVVRRGFHAFKHSYRWRDRPQSKEPR
>NZ_CP053618|6218792:6293539|6275998_6276361_-|WP_045953231.1|DBSCAN-SWA
MSRLGLSGEELLWNWARWCWSGPTVGNMAQFIPEEDEFRPILIDQAVAVDGLHRALPRHEAMIIIAEYPQRHERFAGLEPLTRAERARDWISRITGIYLTHAQYRQYLGFFKDKVQREVW
>NZ_CP053618|6218792:6293539|6227958_6229107_-|WP_173011186.1|DBSCAN-SWA
MTTASVTLDTLDTPCLLLDETRMTRNIKRLNRLMAGHGVQLRPHLKTPKSIEVARRVMARPEGPAAVSTLQEAEQFAAAGVTDLLYAVGVAPAKLERVLALRRGGVDLTVVVDSVEAAQAVAARALEEGAAIPALIEIDCDGHRAGVQPGQAGQLLEIARTLHAAGCLRGVMTHAGESYGCRSVEAIADMAEQERLAAVGCAETIRAAGLPCPVVSVGSTPTAHFARNLEGVTEVRAGVYVFFDLVMAGLGVCAVDDIAASVLTTVIGHQPDKGWILVDAGWMAMSRDRGTARQPVDQLYGLVCDADGQVYPDLLLAETNQEQGIIKLRAGSGATLPDLPLGTRLRIVPNHACATCAQHDAYAVVRSGDRQVVAQWQRFRGW
>NZ_CP053618|6218792:6293539|6240477_6242157_-|WP_024069448.1|DBSCAN-SWA
MIGLPSRKPRKDRAGMTRGEPLRLARQEQADRLGGEHFDMLIVGGGITGAYAALDASLRGYRVALVEKDDFASGTSSKSSKMVHGGLRYIEQGNLGLVRHSLHERQRLRRNARHLVQRLPFLFPLLERDGVFDKRLAKAFESLLWTYDLAGGWREGILHQKLTPEEVLSHCPTFKQDGLLGGFLYFDARVDDARLTLAVARTAAFHGAAVLNHARAIEVTRDTHGKVDGAIVQAGQAEIRVRANVVIMATGVWLRDWNGSRKGDPQALHIRPAKGVHVAVPWLKVRNDCTVTIPVPGRSRRATITRWGNVSYLGTTDEDYAGDLDDVHCTRRELDFLLEGARSALKTDLRAEDVVGSIAGCRPLVAPPGGKTLEIKRNHEIRIAADGLVTIVGGKLTTSRHMAEQTIDAAQKVLGRKARCVTASAFLLGAAGYDPQAIVASGGLSAHLGERYGTEARFVSDLMQQTPALAAPLVPGLPYTEAEALYAVRHELAATVEDVLSRRMRARLMARDASAEAAERVGKILQAELGLSDAAVAQQVRSYRAAIEHEKSVLMGDDS
>NZ_CP053618|6218792:6293539|6260738_6261080_-|WP_045953223.1|tail|DBSCAN-SWA
MSNLEVFQWSPRRNPQAEVKFRILRAQFGDGYEQVVGDGINNRTESWPLSFFGSESEIRPIKDFLDRHGASQAFLWTAPLGTQTSYRAGDYQLVAMGGGWYTISVTFTQRHAP
>NZ_CP053618|6218792:6293539|6227536_6227932_-|WP_020928333.1|DBSCAN-SWA
MDIISTPHATPPAGHYSQAVRANGFVFVSGQLGFLPPVQPGEPPRLAQGVAAQTEAALRSLAAILQAAGTSMSAVVNVTVYIPDVGMWNEVNGVYERSFGDHRPARAIVPTRELHYGALVEISAVAVAPQA
>NZ_CP053618|6218792:6293539|6276852_6277257_-|WP_020928374.1|DBSCAN-SWA
MASNYTPAAIRRLIAADAAQKRFQALGRLPKDKMNGTEKAYSMRLEAMRQRGEILGWLFHPLRVRLADSTYYEVDFLVLQADMRMAIHEVKGGYTTDKGQIKIRLCAEVLPWFVFYKATKQPERRGGGWVLEEY
>NZ_CP053618|6218792:6293539|6292321_6293539_+|WP_045953239.1|integrase|DBSCAN-SWA
MGRDGRGVKAASESSIEITFQYKGRRCRERIPLKPTPANLRRAEQHRAAILHAISTGVFDYAATFPNSARAGTYADTPGQILSVEKYLDGWLDARKPTLKSSTYQGYRSIVLGQLIPKFGKEMLGDLKWPAIKSWLAGLGGDKPVSNKRLSNIQSCLRSALNDAVEDELLDENCMRGRHYSRQAQPVEEGDDDEVDPFTPDEQAAILSELPEQTRNYALFALWTGLRPSEQIALNWSDVDFARGVVLVRKAITRAAKGVAELPKTKSSRREVKILAPALAAINGQKAHTWVGAEPHGELFRNPGTGERWSSSQAVQKVWATALKRAKVRYRRPYQMRHTFASMMLSAGEHPMWVAQQMGHKDWAMIIRVYGKWMPSADKEAGSRAVRLFGDARPINEPRRRAKAS
>NZ_CP053618|6218792:6293539|6282332_6282617_+|WP_045953233.1|DBSCAN-SWA
MYFVLFIVAIALNPVLAPISLAMIWLFVVGSVGYLIFSKEKPEGGLRADTVLGLIVLTFCVPMVIVEMWQDLGVKVPYSFVWSMAKYSFLRIAS
>NZ_CP053618|6218792:6293539|6257432_6258206_-|WP_045953221.1|DBSCAN-SWA
MRKKTMEAIRAHAVAEYPRECCGLVVMAARRESYVPCRNAAAAGDHFVLAPDDYAAAEDAGRVVAIVHSHPDDTPAPSEADRVACEATGLPWYIVEVSKDDAGAVVAGEVRGFTPVGFEAPLLGRQFAHGVLDCYSLVRDWYRRERGIELLDFQREDGWWEPGREGDLYMDHYAEAGFRPLQAGEDMAPGDVILMQVRSNRANHAGVFLGAEGLKEAPGLFSVPDAMLHHLYGRQSERVVYGGYWREATRLVLRYQG
>NZ_CP053618|6218792:6293539|6265925_6266129_-|WP_020928363.1|DBSCAN-SWA
MSAMKPAGAPETDADTETVGTPSAAISPAAAAPDKFHGQGGSYVRDPATGERVLVERTSPCDCGGAS
>NZ_CP053618|6218792:6293539|6264957_6265893_-|WP_020928362.1|DBSCAN-SWA
MAKSIRKTLLLAKIQTAEGVDPVPTGAANAILLRNVTATPLSAEFVERALLRPYMGNAGQVATTQYAQIEGEVELAGSGTAGKAPAWGPLLRACGFAETVTTGTDVRYLPVSENFERIALHYYLDGVFHKILDARGTVSFDLTAKGIPFMRFRFMGVYLPITDGANPTDVDYSAFQIPKGVNKANTPAWSLGSYSGCLQSLTFDIANQLVWRSLIGCEGAEITDRQPTGKISLELPRIAQLDWPAIVLSGEGKALAIQHGTAAGNIVEIKAPTAQLTNPAYSDQGNVAMLGLDMNVNPGPEGNDELEIIVR
>NZ_CP053618|6218792:6293539|6266574_6266877_-|WP_006387637.1|DBSCAN-SWA
MWDNAIFDEAFDQAGMRELASLDGVVPAVDFMVRFDRPDVIDEANLVHSTDYEIEFTTASAPGLKYHSRVRIGGKLYRVRQEPTVRGDGYWTRALLELLP
>NZ_CP053618|6218792:6293539|6245880_6246240_+|WP_054447773.1|DBSCAN-SWA
MTIVVYAANARALWETIQADIAPIGARATTSGNSWRKDDSGRAAKIYRATPTGQHDERAYFVGTVRTGQLMLLDLLPGSEALSWPLFGALHGHLSGMLLATYPDAILSLNLFPNRPTEI
>NZ_CP053618|6218792:6293539|6274925_6275657_+|WP_144415881.1|DBSCAN-SWA
MTIDNPAHRLWLLLSEARTIEITKNCKQAWAQLFNVKATSPDVFERLGKVMQLPSQIIAALKEEHEDELTIAHYWQTQLDTAFSRQNLADTWQSFIGNIDNHSINYLKGHAKILNGGKQLKALELDTLEQARKDLSELLGEVLKDDSIPVSIRQALARNLRAIIISLEEYKLTGSAGVFDSIAILYGQALFDVPYRQSIKADTPFGEKLSSILSGLANSMTVLLGTAQLTNLSESILLLAQKT
>NZ_CP053618|6218792:6293539|6230819_6232010_-|WP_026384511.1|DBSCAN-SWA
MSNPYRELFQAPGAAGFVAACAVARLALPMIGIGIITMLSQVRGAYTLAGAVAATFALATALLAPRISRLVDRHGQGRVLPLAAGASVAGLIGLAACVRLQAPDWTLFVFAALAGSLPSMPAMARARWTEIYRDRPQLRTAYALESVLDELSFIIGPPLAVGLCVILFPEAGPLGAALLLGLGVTAFVLQRATAPAVQPREAGRETSVLGVPLMRQLTAMMAAMGVIVGTIDVMSVAFARQQGLPAGASMVLSAYALGSCVAGLAFGVLKFQTPLARLLAVAASVTAFTTLPLLWVGDLLTLSLGVLLAGLSFAPTMIIAMALVESTVPGRRLTEGLTWLVTGLGAGVAAGAALAGWIVDHHGVGAGFWTAVGAGAVVLLVAVYAARGARPAPAAA
>NZ_CP053618|6218792:6293539|6283590_6283959_+|WP_020928385.1|DBSCAN-SWA
MQSNLILTTAQAQAVYSAMCALDALGPDHGAEFHLGDWVYVRRVHLDGAIRIEDRADGDDERHDDLAAFAAAYGLRQPPDAAPLLEALQAALAYNDSVMSADGSGQFSWGPIARAAIAQATA
>NZ_CP053618|6218792:6293539|6285879_6286158_+|WP_020928389.1|DBSCAN-SWA
MKRIVILAAAGLAAVLGATFALGNVVGARDRELLAKDDKGRATMLARSCGKHGRLLLDPVQNEYVCAWTNPDGATVTAEIPQYPYLDQLAQR
>NZ_CP053618|6218792:6293539|6226262_6226661_-|WP_006386189.1|DBSCAN-SWA
MKKPAERDCIALVPGYSGQAAKLFLTRAEDGAIAGVTVFDLLGHVKHQGDAQAAADWVAAWLAQEADNRKARRTQLLAQMFLCKLADDEKAAFLDAQKPLLAALAAAGVRSRSVAATSGAARRSLGPAVRKP
>NZ_CP053618|6218792:6293539|6218792_6220091_-|WP_006386181.1|protease|DBSCAN-SWA
MPEKKGSADAKVLHCSFCNKSQHEVRKLIAGPSVFICDECIDLCNDIIREEAQATARAAIRSELPTPAEIKTFLDQYVIGQTSPKRMLAVAVYNHYKRIRHGEIKGDEVELSKSNIMLIGPTGSGKTLLAQTLARMLNVPFVMADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQRAIIYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQDFVQVDTTNILFIVGGAFDGLEKVIRDRTEKSGIGFSASVRAKSERGVGELFSEVEPEDLIKFGLIPELVGRLPVVATLDELDEAALVQILTEPKNALLKQFQKLFAMEGAELDVRPAALKAIARKALKRKTGARGLRSIIEQALLDTMYDLPSQGNVKRVVLDEGAIEGEGKPLLIYADEEGTAEKPERGEVRDAAA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006386181.1|6218792_6220091_-|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.7e-130	54.1
WP_006386182.1|6220192_6220846_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.2e-54	55.7
WP_006386183.1|6220850_6222161_-	trigger factor	NA	NA	NA	NA
WP_006386184.1|6222329_6223085_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_006386185.1|6223347_6223893_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	1.3e-20	32.7
WP_006225311.1|6223991_6224198_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.4e-15	59.7
WP_172999574.1|6224490_6225054_-	DUF924 family protein	A0A1V0SIY0	Klosneuvirus	3.1e-17	41.2
WP_006220190.1|6225278_6225482_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	7.3e-17	63.6
WP_006386188.1|6225851_6226172_-	hypothetical protein	NA	NA	NA	NA
WP_006386189.1|6226262_6226661_-	hypothetical protein	NA	NA	NA	NA
WP_006386190.1|6226783_6227071_+	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_173011185.1|6227164_6227437_-	hypothetical protein	NA	NA	NA	NA
WP_020928333.1|6227536_6227932_-	endoribonuclease L-PSP	NA	NA	NA	NA
WP_173011186.1|6227958_6229107_-	DSD1 family PLP-dependent enzyme	NA	NA	NA	NA
WP_173011187.1|6229253_6230171_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_020928335.1|6230353_6230752_-	RidA family protein	NA	NA	NA	NA
WP_026384511.1|6230819_6232010_-	MFS transporter	NA	NA	NA	NA
WP_006386197.1|6232143_6232725_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_006386198.1|6232848_6233376_+	hypothetical protein	NA	NA	NA	NA
WP_020928338.1|6233446_6233752_+	hypothetical protein	NA	NA	NA	NA
WP_006386200.1|6233775_6234084_-	hypothetical protein	NA	NA	NA	NA
WP_006386201.1|6234150_6235008_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.1e-50	41.7
WP_020928339.1|6235244_6236204_+	HD domain-containing protein	NA	NA	NA	NA
WP_020928340.1|6236227_6237445_+	hypothetical protein	NA	NA	NA	NA
WP_024069446.1|6237488_6238199_-	aquaporin Z	A0A1B1ISL4	uncultured_Mediterranean_phage	1.2e-05	50.0
WP_006386205.1|6238341_6238923_-	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_024069447.1|6238924_6240481_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_024069448.1|6240477_6242157_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_006386208.1|6242153_6243692_-	glycerol kinase	NA	NA	NA	NA
WP_006386209.1|6243706_6245164_-	MFS transporter	NA	NA	NA	NA
WP_020928345.1|6245416_6245776_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_054447773.1|6245880_6246240_+	hypothetical protein	NA	NA	NA	NA
WP_054447772.1|6246252_6246765_+	hypothetical protein	NA	NA	NA	NA
WP_108914266.1|6246866_6247142_-	hypothetical protein	NA	NA	NA	NA
6247405:6247436	attL	NA	NA	NA	NA
WP_045953215.1|6248850_6249108_-	hypothetical protein	NA	NA	NA	NA
WP_045953594.1|6249383_6249611_+	hypothetical protein	NA	NA	NA	NA
WP_045953216.1|6249861_6250899_+	ParA family protein	NA	NA	NA	NA
WP_020928352.1|6251394_6251661_-	hypothetical protein	NA	NA	NA	NA
WP_020928353.1|6251663_6252155_-	hypothetical protein	I6NSS1	Burkholderia_phage	9.9e-44	58.0
WP_020928354.1|6252158_6252602_-	hypothetical protein	A0A0U5LBV3	unidentified_phage	4.3e-14	41.4
WP_045953217.1|6252696_6253362_-	hypothetical protein	NA	NA	NA	NA
WP_045953218.1|6253361_6253652_-	hypothetical protein	NA	NA	NA	NA
WP_020928355.1|6253653_6256821_-	host specificity protein J	Q6JIL2	Burkholderia_virus	1.8e-266	46.4
WP_045953220.1|6256817_6257429_-|tail	tail assembly protein	Q6JIL3	Burkholderia_virus	2.7e-54	55.9
WP_045953221.1|6257432_6258206_-	C40 family peptidase	A4JX14	Burkholderia_virus	5.0e-66	51.7
WP_045953222.1|6258208_6258937_-|tail	phage minor tail protein L	Q6JIL5	Burkholderia_virus	2.3e-68	57.0
WP_052719203.1|6258940_6259480_-	hypothetical protein	NA	NA	NA	NA
WP_045953223.1|6260738_6261080_-|tail	phage tail protein	Q6UAW6	Klebsiella_phage	7.4e-30	54.5
WP_045953224.1|6261076_6264052_-|tail	phage tail tape measure protein	A0A2H4J9A1	uncultured_Caudovirales_phage	1.3e-93	32.6
WP_006387642.1|6264085_6264397_-	DUF1799 domain-containing protein	NA	NA	NA	NA
WP_020928361.1|6264462_6264882_-	hypothetical protein	NA	NA	NA	NA
WP_020928362.1|6264957_6265893_-	hypothetical protein	G8CLB2	Synechococcus_phage	3.8e-60	40.9
WP_020928363.1|6265925_6266129_-	hypothetical protein	NA	NA	NA	NA
WP_006387638.1|6266155_6266578_-	hypothetical protein	NA	NA	NA	NA
WP_006387637.1|6266574_6266877_-	hypothetical protein	NA	NA	NA	NA
WP_020928365.1|6266882_6267887_-|capsid	major capsid protein	A0A2H4J890	uncultured_Caudovirales_phage	4.1e-68	42.2
WP_020928366.1|6267967_6268318_-|head	head decoration protein	A0A2H4JF15	uncultured_Caudovirales_phage	2.5e-17	49.6
WP_045953226.1|6268345_6269455_-|protease	Clp protease ClpP	A0A2H4JDI2	uncultured_Caudovirales_phage	1.4e-45	35.8
WP_045953227.1|6269483_6270983_-|portal	phage portal protein	A0A2H4JFL5	uncultured_Caudovirales_phage	1.9e-125	50.1
WP_020928369.1|6270979_6271186_-	hypothetical protein	A0A2H4EUL1	Aeromonas_phage	4.5e-06	42.6
WP_080945041.1|6271233_6273228_-|terminase	phage terminase large subunit family protein	R9TMM4	Vibrio_phage	1.5e-114	37.2
WP_006387630.1|6273305_6273803_-|terminase	terminase small subunit	NA	NA	NA	NA
WP_045953229.1|6273799_6274585_-	hypothetical protein	A0A1B0Z000	Pseudomonas_phage	1.5e-33	39.7
WP_144415881.1|6274925_6275657_+	hypothetical protein	NA	NA	NA	NA
WP_045953231.1|6275998_6276361_-	hypothetical protein	NA	NA	NA	NA
WP_020928373.1|6276353_6276557_-	hypothetical protein	NA	NA	NA	NA
WP_020928374.1|6276852_6277257_-	hypothetical protein	NA	NA	NA	NA
WP_020928376.1|6278269_6279010_-	phage antirepressor KilAC domain-containing protein	A0A2H4IZE1	uncultured_Caudovirales_phage	5.9e-24	44.0
WP_020928377.1|6279006_6279297_-	hypothetical protein	NA	NA	NA	NA
WP_045953232.1|6279293_6279704_-	hypothetical protein	NA	NA	NA	NA
WP_020928379.1|6279700_6280144_-	phage regulatory CII family protein	Q3HQZ3	Burkholderia_phage	2.6e-27	46.9
WP_020928380.1|6280394_6280616_+	hypothetical protein	NA	NA	NA	NA
WP_080944995.1|6280708_6280984_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_052719205.1|6281091_6281823_+	helix-turn-helix transcriptional regulator	J7I4M9	Acinetobacter_phage	3.1e-25	32.5
WP_045953233.1|6282332_6282617_+	hypothetical protein	NA	NA	NA	NA
WP_020928382.1|6282648_6282813_+	hypothetical protein	NA	NA	NA	NA
WP_045953234.1|6282822_6283185_+	hypothetical protein	NA	NA	NA	NA
WP_020928384.1|6283264_6283555_+	hypothetical protein	NA	NA	NA	NA
WP_020928385.1|6283590_6283959_+	hypothetical protein	NA	NA	NA	NA
WP_020928386.1|6283999_6284185_+	hypothetical protein	NA	NA	NA	NA
WP_045953236.1|6284186_6284390_+	hypothetical protein	NA	NA	NA	NA
WP_020928387.1|6284412_6284667_+	hypothetical protein	NA	NA	NA	NA
WP_020928388.1|6284696_6284927_+	hypothetical protein	NA	NA	NA	NA
WP_144415882.1|6285323_6285647_-	hypothetical protein	NA	NA	NA	NA
WP_020928389.1|6285879_6286158_+	hypothetical protein	NA	NA	NA	NA
WP_020928390.1|6286217_6286874_+	hypothetical protein	A0A2H4J8A1	uncultured_Caudovirales_phage	2.3e-11	30.4
WP_020928391.1|6286876_6287332_+	single-stranded DNA-binding protein	F8TUL2	EBPR_podovirus	3.2e-36	49.7
WP_020928392.1|6287355_6287715_+	hypothetical protein	NA	NA	NA	NA
WP_020928393.1|6287736_6288636_+	recombination-associated protein RdgC	A0A218M310	Acidovorax_phage	1.3e-54	38.3
WP_020928394.1|6288651_6289446_+	hypothetical protein	C7BGF1	Burkholderia_phage	6.5e-85	63.8
WP_045953237.1|6289442_6289649_+	hypothetical protein	NA	NA	NA	NA
WP_173011188.1|6289645_6289984_+	hypothetical protein	NA	NA	NA	NA
WP_173011189.1|6290221_6290620_+	hypothetical protein	NA	NA	NA	NA
WP_045953238.1|6290619_6290844_+	hypothetical protein	NA	NA	NA	NA
WP_158324534.1|6290840_6291011_+	hypothetical protein	NA	NA	NA	NA
WP_080945043.1|6291621_6292179_+	DUF550 domain-containing protein	A0A1B0YZX5	Pseudomonas_phage	5.1e-36	66.4
WP_045953239.1|6292321_6293539_+|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	1.2e-117	56.2
6295799:6295830	attR	NA	NA	NA	NA