CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053640	Staphylococcus aureus strain 14505 chromosome, complete genome	10 crisprs	csa3,cas3,DinG,DEDDh,WYL,RT	8	2	210	1
NZ_CP053641	Staphylococcus aureus strain 14505 plasmid unnamed, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053640_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_1

454665-454749

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_1

>merge|NZ_CP053640|1|454665-454749|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACACAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>NZ_CP053640|1|1|454665-454749|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACACAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_001019324.1\|445853_446438_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224627
NZ_CP053640.1\|WP_000439693.1\|448328_448790_+\|ComE-operon-protein-2	unknown	unknown	gnl\|CDD\|131622
NZ_CP053640.1\|WP_000182211.1\|457291_457918_+\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|237622
NZ_CP053640.1\|WP_001802022.1\|447550_448237_+\|ComEA-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|224472
NZ_CP053640.1\|WP_000048060.1\|464435_464612_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP053640.1\|WP_000034716.1\|457986_459819_+\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_CP053640.1\|WP_000725167.1\|445294_445864_+\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl\|CDD\|273101
NZ_CP053640.1\|WP_001190120.1\|462037_462790_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NZ_CP053640.1\|WP_001282563.1\|451052_452027_+\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235511
NZ_CP053640.1\|WP_001104607.1\|461097_462036_+\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_CP053640.1\|WP_001119021.1\|459954_461094_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|237656
NZ_CP053640.1\|WP_001274017.1\|452071_452323_-\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943
NZ_CP053640.1\|WP_000084830.1\|446794_447511_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_CP053640.1\|WP_001802667.1\|464855_465539_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223961
NZ_CP053640.1\|WP_000108667.1\|462796_464143_+\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl\|CDD\|223694
NZ_CP053640.1\|WP_001557362.1\|448794_450996_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|225212
NZ_CP053640.1\|WP_000218103.1\|455057_456182_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP053640.1\|WP_000368338.1\|452668_454492_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP053640.1\|WP_001088020.1\|446438_446792_+\|ribosome-silencing-factor	unknown	unknown	gnl\|CDD\|223870
NZ_CP053640.1\|WP_000627144.1\|456282_457260_+\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|273017

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_001019324.1\|445853_446438_+\|HD-domain-containing-protein	gnl\|CDD\|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
NZ_CP053640.1\|WP_000439693.1\|448328_448790_+\|ComE-operon-protein-2	gnl\|CDD\|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
NZ_CP053640.1\|WP_000182211.1\|457291_457918_+\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
NZ_CP053640.1\|WP_001802022.1\|447550_448237_+\|ComEA-family-DNA-binding-protein	gnl\|CDD\|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.06297e-33
NZ_CP053640.1\|WP_000048060.1\|464435_464612_+\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
NZ_CP053640.1\|WP_000034716.1\|457986_459819_+\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_CP053640.1\|WP_000725167.1\|445294_445864_+\|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl\|CDD\|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
NZ_CP053640.1\|WP_001190120.1\|462037_462790_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
NZ_CP053640.1\|WP_001282563.1\|451052_452027_+\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	4.1415e-104
NZ_CP053640.1\|WP_001104607.1\|461097_462036_+\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
NZ_CP053640.1\|WP_001119021.1\|459954_461094_+\|molecular-chaperone-DnaJ	gnl\|CDD\|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
NZ_CP053640.1\|WP_001274017.1\|452071_452323_-\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
NZ_CP053640.1\|WP_000084830.1\|446794_447511_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.79783e-16
NZ_CP053640.1\|WP_001802667.1\|464855_465539_+\|hypothetical-protein	gnl\|CDD\|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	8.78003e-63
NZ_CP053640.1\|WP_000108667.1\|462796_464143_+\|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl\|CDD\|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
NZ_CP053640.1\|WP_001557362.1\|448794_450996_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	3.64233e-90
NZ_CP053640.1\|WP_000218103.1\|455057_456182_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP053640.1\|WP_000368338.1\|452668_454492_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP053640.1\|WP_001088020.1\|446438_446792_+\|ribosome-silencing-factor	gnl\|CDD\|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47
NZ_CP053640.1\|WP_000627144.1\|456282_457260_+\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119

>NZ_CP053640.1|WP_000368338.1|452668_454492_+|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>NZ_CP053640.1|WP_001274017.1|452071_452323_-|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>NZ_CP053640.1|WP_001282563.1|451052_452027_+|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYETEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>NZ_CP053640.1|WP_001557362.1|448794_450996_+|DNA-internalization-related-competence-protein-ComEC/Rec2
MLYVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>NZ_CP053640.1|WP_000439693.1|448328_448790_+|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>NZ_CP053640.1|WP_001802022.1|447550_448237_+|ComEA-family-DNA-binding-protein
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>NZ_CP053640.1|WP_000084830.1|446794_447511_+|class-I-SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDTERLFFIAKK
>NZ_CP053640.1|WP_001088020.1|446438_446792_+|ribosome-silencing-factor
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>NZ_CP053640.1|WP_001019324.1|445853_446438_+|HD-domain-containing-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>NZ_CP053640.1|WP_000725167.1|445294_445864_+|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
>NZ_CP053640.1|WP_000218103.1|455057_456182_+|oxygen-independent-coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>NZ_CP053640.1|WP_000627144.1|456282_457260_+|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>NZ_CP053640.1|WP_000182211.1|457291_457918_+|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>NZ_CP053640.1|WP_000034716.1|457986_459819_+|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>NZ_CP053640.1|WP_001119021.1|459954_461094_+|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>NZ_CP053640.1|WP_001104607.1|461097_462036_+|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>NZ_CP053640.1|WP_001190120.1|462037_462790_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>NZ_CP053640.1|WP_000108667.1|462796_464143_+|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>NZ_CP053640.1|WP_000048060.1|464435_464612_+|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>NZ_CP053640.1|WP_001802667.1|464855_465539_+|hypothetical-protein
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD

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Crispr_ID: NZ_CP053640_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_2

1246783-1246864

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_2

>merge|NZ_CP053640|2|1246783-1246864|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCTCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_CP053640|2|2|1246783-1246864|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCTCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000974460.1\|1251019_1251442_+\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_CP053640.1\|WP_000422908.1\|1249533_1250073_-\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_CP053640.1\|WP_000168845.1\|1239967_1240729_-\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_CP053640.1\|WP_001065801.1\|1245491_1245788_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP053640.1\|WP_000150011.1\|1250155_1250872_-\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_CP053640.1\|WP_001006450.1\|1237206_1238457_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_CP053640.1\|WP_000290491.1\|1248024_1248405_-\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_CP053640.1\|WP_000569883.1\|1251840_1252335_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_CP053640.1\|WP_001140693.1\|1253179_1253761_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP053640.1\|WP_000571213.1\|1244216_1245242_-\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_CP053640.1\|WP_001147952.1\|1249062_1249383_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_CP053640.1\|WP_000752917.1\|1242141_1242336_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_CP053640.1\|WP_001183854.1\|1241056_1241908_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_CP053640.1\|WP_000255551.1\|1252489_1253107_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_CP053640.1\|WP_000205567.1\|1238562_1239870_-\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_CP053640.1\|WP_000520231.1\|1243528_1244224_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_CP053640.1\|WP_001018962.1\|1245780_1246167_-\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_CP053640.1\|WP_000589549.1\|1248562_1248919_-\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_CP053640.1\|WP_000932225.1\|1246967_1247846_-\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_CP053640.1\|WP_000732324.1\|1242689_1243511_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000974460.1\|1251019_1251442_+\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_CP053640.1\|WP_000422908.1\|1249533_1250073_-\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_CP053640.1\|WP_000168845.1\|1239967_1240729_-\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NZ_CP053640.1\|WP_001065801.1\|1245491_1245788_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_CP053640.1\|WP_000150011.1\|1250155_1250872_-\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	3.2619e-146
NZ_CP053640.1\|WP_001006450.1\|1237206_1238457_-\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_CP053640.1\|WP_000290491.1\|1248024_1248405_-\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
NZ_CP053640.1\|WP_000569883.1\|1251840_1252335_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	1.02873e-46
NZ_CP053640.1\|WP_001140693.1\|1253179_1253761_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.2875e-48
NZ_CP053640.1\|WP_000571213.1\|1244216_1245242_-\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.03316e-170
NZ_CP053640.1\|WP_001147952.1\|1249062_1249383_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
NZ_CP053640.1\|WP_000752917.1\|1242141_1242336_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_CP053640.1\|WP_001183854.1\|1241056_1241908_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
NZ_CP053640.1\|WP_000255551.1\|1252489_1253107_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	2.60719e-61
NZ_CP053640.1\|WP_000205567.1\|1238562_1239870_-\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135
NZ_CP053640.1\|WP_000520231.1\|1243528_1244224_-\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.66296e-99
NZ_CP053640.1\|WP_001018962.1\|1245780_1246167_-\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_CP053640.1\|WP_000589549.1\|1248562_1248919_-\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_CP053640.1\|WP_000932225.1\|1246967_1247846_-\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	3.13065e-77
NZ_CP053640.1\|WP_000732324.1\|1242689_1243511_-\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112

>NZ_CP053640.1|WP_001018962.1|1245780_1246167_-|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_CP053640.1|WP_001065801.1|1245491_1245788_-|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_CP053640.1|WP_000571213.1|1244216_1245242_-|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_CP053640.1|WP_000520231.1|1243528_1244224_-|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_CP053640.1|WP_000732324.1|1242689_1243511_-|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_CP053640.1|WP_000752917.1|1242141_1242336_-|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_CP053640.1|WP_001183854.1|1241056_1241908_+|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_CP053640.1|WP_000168845.1|1239967_1240729_-|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_CP053640.1|WP_000205567.1|1238562_1239870_-|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_CP053640.1|WP_001006450.1|1237206_1238457_-|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF
>NZ_CP053640.1|WP_000932225.1|1246967_1247846_-|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMQEETLSQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLNDLPEQQELFPVNEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQVHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_CP053640.1|WP_000290491.1|1248024_1248405_-|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>NZ_CP053640.1|WP_000589549.1|1248562_1248919_-|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_CP053640.1|WP_001147952.1|1249062_1249383_+|thioredoxin-family-protein
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_CP053640.1|WP_000422908.1|1249533_1250073_-|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_CP053640.1|WP_000150011.1|1250155_1250872_-|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_CP053640.1|WP_000974460.1|1251019_1251442_+|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_CP053640.1|WP_000569883.1|1251840_1252335_+|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNAYFDEHWLFYDLINK
>NZ_CP053640.1|WP_000255551.1|1252489_1253107_+|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIISPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLLF
>NZ_CP053640.1|WP_001140693.1|1253179_1253761_-|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL

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Crispr_ID: NZ_CP053640_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_3

1295523-1295601

Unclear

Consensus_repeat	Method
AGAATTTCGAAAAGAAATTCTACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_3

>merge|NZ_CP053640|3|1295523-1295601|CRISPRCasFinder
AGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACA

>NZ_CP053640|3|3|1295523-1295601|CRISPRCasFinder
AGAATTTCGAAAAGAAATTCTACA	GGCAATGCAAGTTGGCGGGGCCCCAACACAG
AGAATTTCGAAAAGAAATTCTACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000057543.1\|1291546_1292986_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NZ_CP053640.1\|WP_000958224.1\|1294331_1295264_-\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NZ_CP053640.1\|WP_000617735.1\|1307710_1308283_-\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NZ_CP053640.1\|WP_000506531.1\|1304765_1307297_-\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NZ_CP053640.1\|WP_000638419.1\|1301035_1301272_-\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234
NZ_CP053640.1\|WP_000369722.1\|1288747_1289659_-\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NZ_CP053640.1\|WP_000134963.1\|1290544_1291480_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_CP053640.1\|WP_000006551.1\|1286700_1287645_-\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NZ_CP053640.1\|WP_001248939.1\|1287755_1288751_-\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP053640.1\|WP_000662677.1\|1295927_1298774_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NZ_CP053640.1\|WP_000513305.1\|1293486_1294326_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NZ_CP053640.1\|WP_001224793.1\|1292993_1293479_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NZ_CP053640.1\|WP_000229241.1\|1298781_1300767_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP053640.1\|WP_000753319.1\|1302092_1302932_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_CP053640.1\|WP_001790092.1\|1304619_1304724_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000538141.1\|1301268_1301919_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NZ_CP053640.1\|WP_010956549.1\|1303340_1304451_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NZ_CP053640.1\|WP_000816304.1\|1284404_1285307_+\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NZ_CP053640.1\|WP_001049165.1\|1285549_1286137_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NZ_CP053640.1\|WP_001792175.1\|1303079_1303187_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000057543.1\|1291546_1292986_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NZ_CP053640.1\|WP_000958224.1\|1294331_1295264_-\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NZ_CP053640.1\|WP_000617735.1\|1307710_1308283_-\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NZ_CP053640.1\|WP_000506531.1\|1304765_1307297_-\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_CP053640.1\|WP_000638419.1\|1301035_1301272_-\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NZ_CP053640.1\|WP_000369722.1\|1288747_1289659_-\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NZ_CP053640.1\|WP_000134963.1\|1290544_1291480_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NZ_CP053640.1\|WP_000006551.1\|1286700_1287645_-\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NZ_CP053640.1\|WP_001248939.1\|1287755_1288751_-\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NZ_CP053640.1\|WP_000662677.1\|1295927_1298774_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NZ_CP053640.1\|WP_000513305.1\|1293486_1294326_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NZ_CP053640.1\|WP_001224793.1\|1292993_1293479_-\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NZ_CP053640.1\|WP_000229241.1\|1298781_1300767_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP053640.1\|WP_000753319.1\|1302092_1302932_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NZ_CP053640.1\|WP_000538141.1\|1301268_1301919_-\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NZ_CP053640.1\|WP_010956549.1\|1303340_1304451_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_CP053640.1\|WP_000816304.1\|1284404_1285307_+\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NZ_CP053640.1\|WP_001049165.1\|1285549_1286137_-\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148

>NZ_CP053640.1|WP_000958224.1|1294331_1295264_-|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NZ_CP053640.1|WP_000513305.1|1293486_1294326_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NZ_CP053640.1|WP_001224793.1|1292993_1293479_-|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NZ_CP053640.1|WP_000057543.1|1291546_1292986_-|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NZ_CP053640.1|WP_000134963.1|1290544_1291480_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NZ_CP053640.1|WP_000369722.1|1288747_1289659_-|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NZ_CP053640.1|WP_001248939.1|1287755_1288751_-|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NZ_CP053640.1|WP_000006551.1|1286700_1287645_-|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NZ_CP053640.1|WP_001049165.1|1285549_1286137_-|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NZ_CP053640.1|WP_000816304.1|1284404_1285307_+|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>NZ_CP053640.1|WP_000662677.1|1295927_1298774_-|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NZ_CP053640.1|WP_000229241.1|1298781_1300767_-|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NZ_CP053640.1|WP_000638419.1|1301035_1301272_-|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NZ_CP053640.1|WP_000538141.1|1301268_1301919_-|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NZ_CP053640.1|WP_000753319.1|1302092_1302932_-|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NZ_CP053640.1|WP_001792175.1|1303079_1303187_-|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NZ_CP053640.1|WP_010956549.1|1303340_1304451_-|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NZ_CP053640.1|WP_001790092.1|1304619_1304724_-|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NZ_CP053640.1|WP_000506531.1|1304765_1307297_-|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NZ_CP053640.1|WP_000617735.1|1307710_1308283_-|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ

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Crispr_ID: NZ_CP053640_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_4

1691700-1691802

Orphan

Consensus_repeat	Method
CAAATTTAATACTCAATTCATATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_4

>merge|NZ_CP053640|4|1691700-1691802|CRISPRCasFinder
CAAATTTAATACTCAATTCATATATAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTTCAAATTTAATACTCAATTCATAAA

>NZ_CP053640|4|4|1691700-1691802|CRISPRCasFinder
CAAATTTAATACTCAATTCATATA	TAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTT
CAAATTTAATACTCAATTCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000158375.1\|1699272_1699854_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_CP053640.1\|WP_001287099.1\|1694128_1694884_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NZ_CP053640.1\|WP_000868256.1\|1698823_1699207_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000159787.1\|1681551_1681824_+\|transposase	unknown	unknown	gnl\|CDD\|225511
NZ_CP053640.1\|WP_000746679.1\|1697927_1698554_+\|NDxxF-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380196
NZ_CP053640.1\|WP_000991018.1\|1692660_1694049_+\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NZ_CP053640.1\|WP_000394698.1\|1689946_1690609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000424963.1\|1683967_1685509_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NZ_CP053640.1\|WP_001792089.1\|1692477_1692576_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000551643.1\|1683318_1683855_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000041880.1\|1682222_1682927_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP053640.1\|WP_000956137.1\|1690726_1691683_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NZ_CP053640.1\|WP_000421411.1\|1688305_1688884_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
NZ_CP053640.1\|WP_000052781.1\|1695375_1695945_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
NZ_CP053640.1\|WP_000466748.1\|1700279_1700531_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_CP053640.1\|WP_000930514.1\|1695960_1697484_+\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
NZ_CP053640.1\|WP_000793023.1\|1687037_1688306_-\|purine-permease	unknown	unknown	gnl\|CDD\|274468
NZ_CP053640.1\|WP_000763767.1\|1689396_1689804_+\|general-stress-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP053640.1\|WP_000211677.1\|1700031_1700241_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000264071.1\|1685533_1687000_-\|IMP-dehydrogenase	unknown	unknown	gnl\|CDD\|235507

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000158375.1\|1699272_1699854_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49
NZ_CP053640.1\|WP_001287099.1\|1694128_1694884_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	4.50551e-88
NZ_CP053640.1\|WP_000159787.1\|1681551_1681824_+\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NZ_CP053640.1\|WP_000264071.1\|1685533_1687000_-\|IMP-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NZ_CP053640.1\|WP_000746679.1\|1697927_1698554_+\|NDxxF-motif-lipoprotein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
NZ_CP053640.1\|WP_000763767.1\|1689396_1689804_+\|general-stress-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
NZ_CP053640.1\|WP_000424963.1\|1683967_1685509_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NZ_CP053640.1\|WP_000041880.1\|1682222_1682927_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.38181e-08
NZ_CP053640.1\|WP_000421411.1\|1688305_1688884_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	1.38815e-118
NZ_CP053640.1\|WP_000052781.1\|1695375_1695945_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NZ_CP053640.1\|WP_000466748.1\|1700279_1700531_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.58864e-09
NZ_CP053640.1\|WP_000930514.1\|1695960_1697484_+\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NZ_CP053640.1\|WP_000793023.1\|1687037_1688306_-\|purine-permease	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.74823e-170
NZ_CP053640.1\|WP_000991018.1\|1692660_1694049_+\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NZ_CP053640.1\|WP_000956137.1\|1690726_1691683_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416

>NZ_CP053640.1|WP_000956137.1|1690726_1691683_+|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NZ_CP053640.1|WP_000394698.1|1689946_1690609_+|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NZ_CP053640.1|WP_000763767.1|1689396_1689804_+|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>NZ_CP053640.1|WP_000421411.1|1688305_1688884_-|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVVEE
>NZ_CP053640.1|WP_000793023.1|1687037_1688306_-|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NZ_CP053640.1|WP_000264071.1|1685533_1687000_-|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NZ_CP053640.1|WP_000424963.1|1683967_1685509_-|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NZ_CP053640.1|WP_000551643.1|1683318_1683855_+|hypothetical-protein
MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NZ_CP053640.1|WP_000041880.1|1682222_1682927_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NZ_CP053640.1|WP_000159787.1|1681551_1681824_+|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI
>NZ_CP053640.1|WP_001792089.1|1692477_1692576_-|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>NZ_CP053640.1|WP_000991018.1|1692660_1694049_+|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>NZ_CP053640.1|WP_001287099.1|1694128_1694884_-|NADPH-dependent-oxidoreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NZ_CP053640.1|WP_000052781.1|1695375_1695945_+|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NZ_CP053640.1|WP_000930514.1|1695960_1697484_+|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NZ_CP053640.1|WP_000746679.1|1697927_1698554_+|NDxxF-motif-lipoprotein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NZ_CP053640.1|WP_000868256.1|1698823_1699207_+|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>NZ_CP053640.1|WP_000158375.1|1699272_1699854_-|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>NZ_CP053640.1|WP_000211677.1|1700031_1700241_+|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFYPILSTFSNIIIHIDHFHANKKDDN
>NZ_CP053640.1|WP_000466748.1|1700279_1700531_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWVGGKLFGQWGPELGSIYILPALIGSIILIAIVTLILRAMRK

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Crispr_ID: NZ_CP053640_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_5

2330751-2330884

Orphan

Consensus_repeat	Method
TATTGAAGAAGATACAA	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP053640_5

>merge|NZ_CP053640|5|2330751-2330884|PILER-CR
TATTGAAGAAGATACAAACAAAGATAAACCTAATTATCAATTTGGTGGACACAACAGTGTTGATTTTGAAGAAGATACACTTCCAAAAGTAAGTGGTCAAAATGAAGGTCAACAAACGATTGAAGAAGATACAA

>NZ_CP053640|5|1|2330751-2330884|PILER-CR
TATTGAAGAAGATACAA	ACAAAGATAAACCTAATTATCAATTTGGTGGACACAACAGTGTTGA
TTTTGAAGAAGATACAC	TTCCAAAAGTAAGTGGTCAAAATGAAGGTCAACAAAC
GATTGAAGAAGATACAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_001117049.1\|2318091_2318508_+\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|227213
NZ_CP053640.1\|WP_000074011.1\|2319595_2320360_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_CP053640.1\|WP_000660710.1\|2314375_2315653_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NZ_CP053640.1\|WP_001205072.1\|2334297_2337261_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|375909
NZ_CP053640.1\|WP_000289136.1\|2318738_2319431_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP053640.1\|WP_000435044.1\|2313217_2313829_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NZ_CP053640.1\|WP_001795286.1\|2338817_2339051_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000481415.1\|2322886_2324245_+\|gluconate-permease	unknown	unknown	gnl\|CDD\|129873
NZ_CP053640.1\|WP_000721336.1\|2331492_2332359_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NZ_CP053640.1\|WP_075339662.1\|2340160_2341969_-\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NZ_CP053640.1\|WP_000088733.1\|2342494_2345356_+\|DUF3427-domain-containing-protein	unknown	unknown	gnl\|CDD\|223989
NZ_CP053640.1\|WP_000386367.1\|2332569_2333313_-\|HTH-type-transcriptional-regulator-SarU	unknown	unknown	gnl\|CDD\|130944
NZ_CP053640.1\|WP_000998872.1\|2333636_2333993_+\|HTH-type-transcriptional-regulator-SarT	unknown	unknown	gnl\|CDD\|130944
NZ_CP053640.1\|WP_095256433.1\|2321216_2322770_+\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NZ_CP053640.1\|WP_000990133.1\|2320512_2321193_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_CP053640.1\|WP_000755947.1\|2342100_2342493_+\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|239517
NZ_CP053640.1\|WP_000217714.1\|2339158_2339467_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000678764.1\|2339610_2339877_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_001557523.1\|2316129_2317953_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|224208
NZ_CP053640.1\|WP_000794606.1\|2324713_2327746_+\|fibronectin-binding-protein-FnbA	unknown	unknown	gnl\|CDD\|371043

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_001117049.1\|2318091_2318508_+\|DUF2188-domain-containing-protein	gnl\|CDD\|227213	COG4876, COG4876, Uncharacterized protein conserved in bacteria [Function unknown].	6.71039e-63
NZ_CP053640.1\|WP_000074011.1\|2319595_2320360_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.31541e-33
NZ_CP053640.1\|WP_000660710.1\|2314375_2315653_+\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.08696e-90
NZ_CP053640.1\|WP_001205072.1\|2334297_2337261_+\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|375909	pfam18483, Bact_lectin, Bacterial lectin. This entry primarily matches to legume-like lectin domains found in prokaryotes.	5.0828e-23
NZ_CP053640.1\|WP_000289136.1\|2318738_2319431_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	8.50652e-86
NZ_CP053640.1\|WP_000435044.1\|2313217_2313829_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	7.26208e-43
NZ_CP053640.1\|WP_000088733.1\|2342494_2345356_+\|DUF3427-domain-containing-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.16603e-91
NZ_CP053640.1\|WP_000481415.1\|2322886_2324245_+\|gluconate-permease	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.72456e-168
NZ_CP053640.1\|WP_000721336.1\|2331492_2332359_+\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	8.48908e-177
NZ_CP053640.1\|WP_075339662.1\|2340160_2341969_-\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_CP053640.1\|WP_000386367.1\|2332569_2333313_-\|HTH-type-transcriptional-regulator-SarU	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	9.70785e-26
NZ_CP053640.1\|WP_000998872.1\|2333636_2333993_+\|HTH-type-transcriptional-regulator-SarT	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	4.06037e-28
NZ_CP053640.1\|WP_095256433.1\|2321216_2322770_+\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NZ_CP053640.1\|WP_000990133.1\|2320512_2321193_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	8.91306e-44
NZ_CP053640.1\|WP_000755947.1\|2342100_2342493_+\|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	1.72286e-56
NZ_CP053640.1\|WP_001557523.1\|2316129_2317953_+\|FUSC-family-protein	gnl\|CDD\|224208	COG1289, COG1289, Predicted membrane protein [Function unknown].	2.12103e-90
NZ_CP053640.1\|WP_000794606.1\|2324713_2327746_+\|fibronectin-binding-protein-FnbA	gnl\|CDD\|371043	pfam10425, SdrG_C_C, C-terminus of bacterial fibrinogen-binding adhesin. This is the C-terminal half of a bacterial fibrinogen-binding adhesin SdrG. SdrG is a Gram-positive cell-wall-anchored adhesin that allows attachment of the bacterium to host tissues via specific binding to the beta-chain of human fibrinogen (Fg). SdrG binds to its ligand with a dynamic "dock, lock, and latch" mechanism which represents a general mode of ligand-binding for structurally related cell wall-anchored proteins in most Gram-positive bacteria. The C-terminal part of SdrG(276-596) is integral to the folding of the immunoglobulin-like whole to create the docking grooves necessary for Fg binding. The domain is associated with families of Cna_B, pfam05738.	2.35555e-25

>NZ_CP053640.1|WP_000794606.1|2324713_2327746_+|fibronectin-binding-protein-FnbA
MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKTSETQTTATNVNHIEETQSYNATVTEQPSNATQVTTEEAPKAVQAPQTAQPANVETVKEEEKPQVKETTQPQDNSGNQRQVDLTPKKVTQNQGTETQVEVAQPRTASESKPRVTRSADVAEAKEASDVSEVKGTDVTSKVTVESGSIEAPQGNKVEPHAGQRVVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEILGNGNIRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPVVYNPGVSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAGGQPTVKVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLDKTYVIHYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADGNGKNGQIIQDNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGDQSFEEDTEKDKPKYEHGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPMPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA
>NZ_CP053640.1|WP_000481415.1|2322886_2324245_+|gluconate-permease
MFNEIWPLISVVLGIVILLVLIIGFKLNKFISLIITSMITALMLGIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHVQWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLPPHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISALGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTAGTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGGVGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVALVVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISLFV
>NZ_CP053640.1|WP_095256433.1|2321216_2322770_+|gluconokinase
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQMHSLIAMNQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPNMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVAVYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>NZ_CP053640.1|WP_000990133.1|2320512_2321193_+|GntR-family-transcriptional-regulator
MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMAKQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRVKNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHLKPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGKDIEGFWLN
>NZ_CP053640.1|WP_000074011.1|2319595_2320360_+|MerR-family-transcriptional-regulator
MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTEQQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLNKIKNVQYYVNEASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIMSSILMKNKWPFLIALPFMNCYGIGVTFYYQQKVAYLCPNCQHIFSPSLWAVIKAKHTATTRRFECPNCHETHYCIEVPKAHMSTEQLEISHIQHNN
>NZ_CP053640.1|WP_000289136.1|2318738_2319431_+|GTP-pyrophosphokinase-family-protein
MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHIYSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAKEHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSIPVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVEDKLQQIHSEITE
>NZ_CP053640.1|WP_001117049.1|2318091_2318508_+|DUF2188-domain-containing-protein
MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEKAEVDSEYATTDNEEHIQEQSNQDKSYFDSESIGNQSGGVRQREPLMDGAHPKVVESFKDV
>NZ_CP053640.1|WP_001557523.1|2316129_2317953_+|FUSC-family-protein
MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVIICNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPINLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYNDKAAFLQVAKTAVDSFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELNAKQIRPLPDELIEMMDHIIAQLDNSDENVRYWRKEVTVTEEFQNLFNHILKIDEMVHANEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFDFEKAYWIPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALFTEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAIGIVIAIIGLFVLGQRTASVLLPNVMAEVVRKEATLFHYLFSENQYKDNVYQKNTAMNLSVKLNNMTQVYNAANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAKHLELNTELEIKILPDLPQYNYIQSAMMNIQHNGFRERDKNV
>NZ_CP053640.1|WP_000660710.1|2314375_2315653_+|MFS-transporter
MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMTKPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLIYLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMFFLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTFQLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK
>NZ_CP053640.1|WP_000435044.1|2313217_2313829_-|DedA-family-protein
MEQIITEFISRFGYAAIFILILLENVLPIVPSEIILTFAGLMSVKSHLSILTLFIIATIASFIGLLILYYICRLISEERLYRFIDRHGKWIKLKSKDLKRANDWFKKYGVWAVFICRFIPVLRVLITIPAGVNRMNVVTFTVISLIGTTIWNFGLILLGRTLSDSFGMLMTGLHTYSRIMYVVIIIAVIYFAIRYIGKRKRVK
>NZ_CP053640.1|WP_000721336.1|2331492_2332359_+|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEAARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYVRQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQEVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLKTQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMREELTRFIKALGL
>NZ_CP053640.1|WP_000386367.1|2332569_2333313_-|HTH-type-transcriptional-regulator-SarU
MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
>NZ_CP053640.1|WP_000998872.1|2333636_2333993_+|HTH-type-transcriptional-regulator-SarT
MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKELSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET
>NZ_CP053640.1|WP_001205072.1|2334297_2337261_+|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MRDKKGPVNKRVDFLSNKLNKYSIRKFTVGTASILIGSLMYLGTQQEAEAAENNIENPTTLKDNVQSKEVKIEEVTNKDTAPQGVEAKSEVTSNKDTIEHEASVKAEDISKKEDTPKEVANVAEVQPKSSVTHNAEAPKVRKARSVDEGSFDITRDSKNVVESTPITIQGKEHFEGYGSVDIQKNPTDLGVSEVTRFNVGNESNGLIGALQLKNKIDFSKDFNFKVRVANNHQSNTTGADGWGFLFSKGNAEEYLTNGGILGDKGLVNSGGFKIDTGYIYTSSMDKTEKQAGQGYRGYGAFVKNDSSGNSQMVGENIDKSKTNFLNYADNSTNTSDGKFHGQRLNDVILTYVASTGKMRAEYAGKTWETSITDLGLSKNQAYNFLITSSQRWGLNQGINANGWMRTDLKGSEFTFTPEAPKTITELEKKVEEIPFKKERKFNPDLAPGTEKVTREGQKGEKTITTPTLKNPLTGEIISKGESKEEITKDPINELTEYGPETIAPGHRDEFDPKLPTGEKEEVPGKPGIKNPETGDVVRPPVDSVTKYGPVKGDSIVEKEEIPFEKERKFNPDLAPGTEKVTREGQKGEKTITTPTLKNPLTGEIISKGESKEEITKDPINELTEYGPETITPGHRDEFDPKLPTGEKEEVPGKPGIKNPETGDVVRPPVDSVTKYGPVKGDSIVEKEEIPFEKERKFNPDLAPGTEKVTREGQKGEKTITTPTLKNPLTGEIISKGESKEEITKDPVNELTEFGGEKIPQGHKDIFDPNLPTDQTEKVPGKPGIKNPDTGKVIEEPVDDVIKHGPKTGTPETKTVEIPFETKREFNPKLQPGEERVKQEGQPGSKTITTPITVNPLTGEKVGEGQPTEEITKQPVDKIVEFGGEKPKDPKGPENPEKPSRPTHPSGPVNPNNPGLSKDRAKPNGPVHSMDKNDKVKKSKIAKESVANQEKKRAELPKTGLESTQKGLIFSSIIGIAGLMLLARRRKN
>NZ_CP053640.1|WP_001795286.1|2338817_2339051_+|hypothetical-protein
MLRSLCKQNRILINAIKVGIEMKYKISLAYNLAIIIGSLIILCILISRGYDIYVILIPILTILASLINLICDIKKHK
>NZ_CP053640.1|WP_000217714.1|2339158_2339467_-|hypothetical-protein
MTVNIVFSIVFCISMVILGIYVAITKDFTLISYINQTTIADKHKNQIAYIFTLCISLSAVFLMSSILCFEYDFIALSFLFLTIALLLIALFYVCFYKITKYP
>NZ_CP053640.1|WP_000678764.1|2339610_2339877_-|hypothetical-protein
MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAHTLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD
>NZ_CP053640.1|WP_075339662.1|2340160_2341969_-|phospho-sugar-mutase
MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHHAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS
>NZ_CP053640.1|WP_000755947.1|2342100_2342493_+|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MKKVINVVGAIIFSDNKILCAQRSEEMSLPLMWEFPGGKIEKNETEKEALIREIREEMKCDLIVGDKVITTEHEYDFGIVKLTTYKCTLNKELPTLTEHKSIKWLSINELDKLNWAPADIPAVNKIMTEG
>NZ_CP053640.1|WP_000088733.1|2342494_2345356_+|DUF3427-domain-containing-protein
MSRLLNDFNQSLKKGFIDKDISHKGNYTPKLLVNNKNEKVLSTIIDELQKCETFYFSVAFITESGLASLKAQLLDLSNKGVKGKILTSNYLGFNSPKMYGELLKLKNVEVRLTDIAGFHAKGYIFEHKDYSSMVIGSSNLTSNALKVNYEHNVLLSTMKNGDLVDSVKNEFELLWQKSTPLTEQWINSYKESFEYRSLEKLAEVEQTQMLLADKVKKSVEIVPNLMQAEALRSLKAIRDKTKDKALIISATGTGKTILCALDVREVNPNKFLFIVHNEGILNRAKEEFKKVLPIKNDSDFGLLTGKHRDVDAKYLFATIQTLSRDDNFKQFDENEFDYIVFDEAHRSAASTYQRVFNYFKPKFMLGMTATPERSDELSIFELFDYNIAYEIRLQAALESDILCPFHYFGVTDYVHQGIKEDDVTKLRYLTSDERVNYIIQKTDYYGYSGEILQGLIFVSSKKEAYDLADKLSSKGIKSVALTGDDSVNYRQIVIEKLKEGKINYIITVDLFNEGIDIPEVNQVVMLRPTESSIIFIQQLGRGLRKSANKEYVTVIDFIGNYKTNYLIPIALSGDQSQNKDNYKKFLTNNDSINGVSTINFEEVAKKQIYNSLDAVSLNQNKLILKAYEEVENRLGHMPLLMDFIQQHSIDPSVIFSKFSNYYEFLLRYKKIDALLTENESKNLVFFSRQIAPGLKRIDSLVLEELLKNELTYDELKNKMLNEVKDITEDDIDTSLRILDFSFYNAGIEKIYGSPIIECNERMIRLSDAFTNALSNQTFKIFLEDLIELSKYNNEKYQKGKNGLILYNKYSREDFSKIFNWNKNGSSVIMGYMIRSQEMPIFITYDKHEDISDSTKYEDEFLSQDELKWFTKSNRTLKSKEVQKILSHRAKGIKMYIFVQKKDDDGIYFYYLGTAGYIEGSEKQDKMPNGSNVVTMDLALDKAVRDDIYRYITN

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Crispr_ID: NZ_CP053640_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_6

2405914-2405992

Orphan

Consensus_repeat	Method
TGCAAGTTGGCGGGGCCCCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_6

>merge|NZ_CP053640|6|2405914-2405992|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACACAGTAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGAGCCCCAACA

>NZ_CP053640|6|5|2405914-2405992|CRISPRCasFinder
TGCAAGTTGGCGGGGCCCCAACA	CAGTAGCTGGCGGAAAGTCAGCTTACAATAATG
TGCAAGTTGGCGGAGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000486487.1\|2408085_2409819_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP053640.1\|WP_001185695.1\|2395300_2397379_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP053640.1\|WP_001110061.1\|2410935_2412294_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_CP053640.1\|WP_000831298.1\|2402838_2403498_-\|membrane-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_001217926.1\|2410271_2410958_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
NZ_CP053640.1\|WP_000482652.1\|2405487_2405595_+\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_CP053640.1\|WP_000101537.1\|2397516_2398926_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_CP053640.1\|WP_001046645.1\|2412295_2413303_+\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_CP053640.1\|WP_000286875.1\|2414406_2415099_+\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_CP053640.1\|WP_000200956.1\|2415109_2415577_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377623
NZ_CP053640.1\|WP_000779360.1\|2404967_2405354_+\|flippase-GtxA	unknown	unknown	gnl\|CDD\|225155
NZ_CP053640.1\|WP_001064825.1\|2406297_2408061_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP053640.1\|WP_000690200.1\|2399211_2400018_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|163441
NZ_CP053640.1\|WP_001080281.1\|2400080_2400737_-\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|227323
NZ_CP053640.1\|WP_000456486.1\|2400849_2401323_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NZ_CP053640.1\|WP_000783428.1\|2415628_2416606_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NZ_CP053640.1\|WP_000916704.1\|2416607_2417555_-\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625
NZ_CP053640.1\|WP_001192075.1\|2401445_2402657_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP053640.1\|WP_000971550.1\|2413280_2414396_+\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_CP053640.1\|WP_001176863.1\|2403557_2404700_-\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000971550.1\|2413280_2414396_+\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	1.12947e-139
NZ_CP053640.1\|WP_001185695.1\|2395300_2397379_-\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.12682e-103
NZ_CP053640.1\|WP_001110061.1\|2410935_2412294_+\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NZ_CP053640.1\|WP_001176863.1\|2403557_2404700_-\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
NZ_CP053640.1\|WP_000779360.1\|2404967_2405354_+\|flippase-GtxA	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.41026e-22
NZ_CP053640.1\|WP_000783428.1\|2415628_2416606_-\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
NZ_CP053640.1\|WP_000101537.1\|2397516_2398926_-\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_CP053640.1\|WP_001046645.1\|2412295_2413303_+\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_CP053640.1\|WP_000286875.1\|2414406_2415099_+\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	1.03044e-132
NZ_CP053640.1\|WP_000200956.1\|2415109_2415577_+\|hypothetical-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.000903859
NZ_CP053640.1\|WP_001080281.1\|2400080_2400737_-\|C39-family-peptidase	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
NZ_CP053640.1\|WP_001064825.1\|2406297_2408061_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	3.20525e-146
NZ_CP053640.1\|WP_000690200.1\|2399211_2400018_+\|metallophosphoesterase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	4.17484e-107
NZ_CP053640.1\|WP_000486487.1\|2408085_2409819_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.92673e-143
NZ_CP053640.1\|WP_000456486.1\|2400849_2401323_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	4.53378e-38
NZ_CP053640.1\|WP_000916704.1\|2416607_2417555_-\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	7.97441e-93
NZ_CP053640.1\|WP_001192075.1\|2401445_2402657_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
NZ_CP053640.1\|WP_001217926.1\|2410271_2410958_+\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	6.55734e-71

>NZ_CP053640.1|WP_000482652.1|2405487_2405595_+|type-I-toxin-antitoxin-system-Fst-family-toxin
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK
>NZ_CP053640.1|WP_000779360.1|2404967_2405354_+|flippase-GtxA
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>NZ_CP053640.1|WP_001176863.1|2403557_2404700_-|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVKFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>NZ_CP053640.1|WP_000831298.1|2402838_2403498_-|membrane-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDDNGGAN
>NZ_CP053640.1|WP_001192075.1|2401445_2402657_-|multidrug-effflux-MFS-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>NZ_CP053640.1|WP_000456486.1|2400849_2401323_+|AraC-family-transcriptional-regulator
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIAKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQANTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>NZ_CP053640.1|WP_001080281.1|2400080_2400737_-|C39-family-peptidase
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>NZ_CP053640.1|WP_000690200.1|2399211_2400018_+|metallophosphoesterase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVMDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>NZ_CP053640.1|WP_000101537.1|2397516_2398926_-|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSILVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>NZ_CP053640.1|WP_001185695.1|2395300_2397379_-|sodium:proton-antiporter
MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIPIQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYFIHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGIISFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNNTLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWNTFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFWYKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKGQAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQHFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPNNQNTKELKRLEDIAKVIETSTLERLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKESKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRAQRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYNEIVLSLQSKH
>NZ_CP053640.1|WP_001064825.1|2406297_2408061_+|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALITYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGNYKKMWDTHMHTKDWGINTGHN
>NZ_CP053640.1|WP_000486487.1|2408085_2409819_+|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDIVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>NZ_CP053640.1|WP_001217926.1|2410271_2410958_+|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCVFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAVVHQDYVNKNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>NZ_CP053640.1|WP_001110061.1|2410935_2412294_+|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEIMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNTFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>NZ_CP053640.1|WP_001046645.1|2412295_2413303_+|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NZ_CP053640.1|WP_000971550.1|2413280_2414396_+|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NZ_CP053640.1|WP_000286875.1|2414406_2415099_+|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFAAAKIGYHRLFDIKPVNTRYGGRIIFVDDCIDLNHYISFLESTPKQVVYETV
>NZ_CP053640.1|WP_000200956.1|2415109_2415577_+|hypothetical-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLSSVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_CP053640.1|WP_000783428.1|2415628_2416606_-|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NZ_CP053640.1|WP_000916704.1|2416607_2417555_-|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN

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Crispr_ID: NZ_CP053640_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_7

2570627-2570707

Orphan

Consensus_repeat	Method
CAAGTTGGCGGGGCCCCAACACAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_7

>merge|NZ_CP053640|7|2570627-2570707|CRISPRCasFinder
CAAGTTGGCGGGGCCCCAACACAGAAGCTGACAGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGA

>NZ_CP053640|7|6|2570627-2570707|CRISPRCasFinder
CAAGTTGGCGGGGCCCCAACACAGA	AGCTGACAGAAAGTCAGCTTACAATAATGTG
CAAGTTGGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000643986.1\|2568841_2569441_+\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NZ_CP053640.1\|WP_000230173.1\|2569460_2570483_+\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NZ_CP053640.1\|WP_000602950.1\|2567650_2568136_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NZ_CP053640.1\|WP_000808495.1\|2568149_2568596_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NZ_CP053640.1\|WP_000866971.1\|2568601_2568835_+\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NZ_CP053640.1\|WP_000503822.1\|2565329_2565836_+\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NZ_CP053640.1\|WP_001161085.1\|2579446_2579764_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_001792132.1\|2570748_2570934_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000413862.1\|2574713_2575979_+\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NZ_CP053640.1\|WP_000592307.1\|2576095_2579263_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NZ_CP053640.1\|WP_000600967.1\|2573317_2574082_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NZ_CP053640.1\|WP_000259717.1\|2566394_2567654_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NZ_CP053640.1\|WP_000184404.1\|2571511_2572723_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NZ_CP053640.1\|WP_000951058.1\|2572715_2573156_-\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670
NZ_CP053640.1\|WP_001549681.1\|2574073_2574325_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000076930.1\|2564294_2565299_+\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NZ_CP053640.1\|WP_000051210.1\|2580008_2580173_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000134526.1\|2565837_2566332_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP053640.1\|WP_000066900.1\|2571059_2571410_+\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NZ_CP053640.1\|WP_000913024.1\|2563519_2564125_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000643986.1\|2568841_2569441_+\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	2.15389e-66
NZ_CP053640.1\|WP_000230173.1\|2569460_2570483_+\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NZ_CP053640.1\|WP_000602950.1\|2567650_2568136_+\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	9.59347e-51
NZ_CP053640.1\|WP_000808495.1\|2568149_2568596_+\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
NZ_CP053640.1\|WP_000866971.1\|2568601_2568835_+\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NZ_CP053640.1\|WP_000503822.1\|2565329_2565836_+\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.42221e-64
NZ_CP053640.1\|WP_000592307.1\|2576095_2579263_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NZ_CP053640.1\|WP_000413862.1\|2574713_2575979_+\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.81413e-143
NZ_CP053640.1\|WP_000600967.1\|2573317_2574082_+\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NZ_CP053640.1\|WP_000259717.1\|2566394_2567654_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	4.50966e-159
NZ_CP053640.1\|WP_000184404.1\|2571511_2572723_-\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.92881e-73
NZ_CP053640.1\|WP_000951058.1\|2572715_2573156_-\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NZ_CP053640.1\|WP_000076930.1\|2564294_2565299_+\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.83722e-133
NZ_CP053640.1\|WP_000134526.1\|2565837_2566332_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.93711e-97
NZ_CP053640.1\|WP_000066900.1\|2571059_2571410_+\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NZ_CP053640.1\|WP_000913024.1\|2563519_2564125_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.78595e-116

>NZ_CP053640.1|WP_000230173.1|2569460_2570483_+|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NZ_CP053640.1|WP_000643986.1|2568841_2569441_+|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NZ_CP053640.1|WP_000866971.1|2568601_2568835_+|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NZ_CP053640.1|WP_000808495.1|2568149_2568596_+|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NZ_CP053640.1|WP_000602950.1|2567650_2568136_+|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NZ_CP053640.1|WP_000259717.1|2566394_2567654_+|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NZ_CP053640.1|WP_000134526.1|2565837_2566332_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NZ_CP053640.1|WP_000503822.1|2565329_2565836_+|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NZ_CP053640.1|WP_000076930.1|2564294_2565299_+|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NZ_CP053640.1|WP_000913024.1|2563519_2564125_+|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG
>NZ_CP053640.1|WP_001792132.1|2570748_2570934_-|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKINYVVIFGSGTEITFSQNLFR
>NZ_CP053640.1|WP_000066900.1|2571059_2571410_+|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NZ_CP053640.1|WP_000184404.1|2571511_2572723_-|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NZ_CP053640.1|WP_000951058.1|2572715_2573156_-|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NZ_CP053640.1|WP_000600967.1|2573317_2574082_+|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NZ_CP053640.1|WP_001549681.1|2574073_2574325_-|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NZ_CP053640.1|WP_000413862.1|2574713_2575979_+|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NZ_CP053640.1|WP_000592307.1|2576095_2579263_+|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHVDGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NZ_CP053640.1|WP_001161085.1|2579446_2579764_-|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NZ_CP053640.1|WP_000051210.1|2580008_2580173_-|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD

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Crispr_ID: NZ_CP053640_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_8

2678659-2678744

Orphan

Consensus_repeat	Method
ACTAATGATACGCAAAAATCAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_8

>merge|NZ_CP053640|8|2678659-2678744|CRISPRCasFinder
ACTAATGATACGCAAAAATCAGTTGGCCCAGTTGCAAACAATAAAGCTAAAGATATGCAAACTAATGATACGCAAAAATCAGTTGG

>NZ_CP053640|8|7|2678659-2678744|CRISPRCasFinder
ACTAATGATACGCAAAAATCAGTTGG	CCCAGTTGCAAACAATAAAGCTAAAGATATGCAA
ACTAATGATACGCAAAAATCAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000047255.1\|2655109_2655793_+\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NZ_CP053640.1\|WP_001802298.1\|2690544_2690649_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000167867.1\|2667102_2668011_+\|arginase	unknown	unknown	gnl\|CDD\|212515
NZ_CP053640.1\|WP_001141007.1\|2658207_2659650_+\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NZ_CP053640.1\|WP_000495669.1\|2691081_2692173_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000927371.1\|2680918_2683051_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP053640.1\|WP_000958531.1\|2659797_2660862_+\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NZ_CP053640.1\|WP_001292149.1\|2680472_2680907_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP053640.1\|WP_000648723.1\|2679366_2680473_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP053640.1\|WP_001792784.1\|2689706_2689865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000334463.1\|2685304_2687110_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP053640.1\|WP_000083807.1\|2683085_2684624_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP053640.1\|WP_000347896.1\|2668199_2669009_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_CP053640.1\|WP_000521495.1\|2669969_2671325_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_CP053640.1\|WP_000636857.1\|2657411_2657885_+\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NZ_CP053640.1\|WP_000908182.1\|2687341_2688124_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP053640.1\|WP_001237506.1\|2655969_2657313_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_CP053640.1\|WP_000370923.1\|2688191_2689049_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP053640.1\|WP_000894032.1\|2669010_2669943_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_CP053640.1\|WP_000884735.1\|2653903_2655091_+\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000047255.1\|2655109_2655793_+\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NZ_CP053640.1\|WP_000167867.1\|2667102_2668011_+\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
NZ_CP053640.1\|WP_001141007.1\|2658207_2659650_+\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.85929e-81
NZ_CP053640.1\|WP_000927371.1\|2680918_2683051_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP053640.1\|WP_000958531.1\|2659797_2660862_+\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NZ_CP053640.1\|WP_001292149.1\|2680472_2680907_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP053640.1\|WP_000648723.1\|2679366_2680473_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP053640.1\|WP_000334463.1\|2685304_2687110_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP053640.1\|WP_000083807.1\|2683085_2684624_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP053640.1\|WP_000347896.1\|2668199_2669009_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NZ_CP053640.1\|WP_000521495.1\|2669969_2671325_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_CP053640.1\|WP_000636857.1\|2657411_2657885_+\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NZ_CP053640.1\|WP_000908182.1\|2687341_2688124_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NZ_CP053640.1\|WP_001237506.1\|2655969_2657313_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.92638e-43
NZ_CP053640.1\|WP_000370923.1\|2688191_2689049_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	2.39536e-58
NZ_CP053640.1\|WP_000894032.1\|2669010_2669943_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NZ_CP053640.1\|WP_000884735.1\|2653903_2655091_+\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149

>NZ_CP053640.1|WP_000521495.1|2669969_2671325_+|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NZ_CP053640.1|WP_000894032.1|2669010_2669943_+|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NZ_CP053640.1|WP_000347896.1|2668199_2669009_+|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NZ_CP053640.1|WP_000167867.1|2667102_2668011_+|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NZ_CP053640.1|WP_000958531.1|2659797_2660862_+|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NZ_CP053640.1|WP_001141007.1|2658207_2659650_+|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NZ_CP053640.1|WP_000636857.1|2657411_2657885_+|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NZ_CP053640.1|WP_001237506.1|2655969_2657313_+|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NZ_CP053640.1|WP_000047255.1|2655109_2655793_+|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NZ_CP053640.1|WP_000884735.1|2653903_2655091_+|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI
>NZ_CP053640.1|WP_000648723.1|2679366_2680473_-|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP053640.1|WP_001292149.1|2680472_2680907_-|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP053640.1|WP_000927371.1|2680918_2683051_-|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP053640.1|WP_000083807.1|2683085_2684624_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP053640.1|WP_000334463.1|2685304_2687110_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP053640.1|WP_000908182.1|2687341_2688124_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP053640.1|WP_000370923.1|2688191_2689049_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTLDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP053640.1|WP_001792784.1|2689706_2689865_-|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP053640.1|WP_001802298.1|2690544_2690649_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP053640.1|WP_000495669.1|2691081_2692173_-|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK

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Crispr_ID: NZ_CP053640_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_9

2690984-2691065

Orphan

Consensus_repeat	Method
AAGAAGCCCCTAACAACTAAAGTTG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_CP053640_9

>merge|NZ_CP053640|9|2690984-2691065|CRISPRCasFinder
AAGAAGCCCCTAACAACTAAAGTTGAAAAGTAGGAGCGCCTGCGCTAAGCGCATGCATAAGAGCCCCTAACAACTAAAGTTG

>NZ_CP053640|9|8|2690984-2691065|CRISPRCasFinder
AAGAAGCCCCTAACAACTAAAGTTG	AAAAGTAGGAGCGCCTGCGCTAAGCGCATGCA
TAAGAGCCCCTAACAACTAAAGTTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_001123303.1\|2698691_2699105_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_CP053640.1\|WP_001802298.1\|2690544_2690649_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000160304.1\|2699868_2700579_-\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP053640.1\|WP_001048259.1\|2671602_2679048_+\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_CP053640.1\|WP_000927371.1\|2680918_2683051_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_CP053640.1\|WP_001292149.1\|2680472_2680907_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_CP053640.1\|WP_000003759.1\|2693417_2693738_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_CP053640.1\|WP_000123398.1\|2696861_2698235_+\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_CP053640.1\|WP_001792784.1\|2689706_2689865_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000334463.1\|2685304_2687110_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_CP053640.1\|WP_000083807.1\|2683085_2684624_-\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_CP053640.1\|WP_000648723.1\|2679366_2680473_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_CP053640.1\|WP_000808817.1\|2695959_2696190_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000908182.1\|2687341_2688124_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_CP053640.1\|WP_000495669.1\|2691081_2692173_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000370923.1\|2688191_2689049_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_CP053640.1\|WP_001024095.1\|2693889_2694555_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NZ_CP053640.1\|WP_000019734.1\|2692438_2693416_-\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_CP053640.1\|WP_000070866.1\|2699304_2699748_+\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_CP053640.1\|WP_001127960.1\|2694990_2695929_+\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_001123303.1\|2698691_2699105_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	3.14887e-46
NZ_CP053640.1\|WP_000160304.1\|2699868_2700579_-\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NZ_CP053640.1\|WP_001048259.1\|2671602_2679048_+\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.2997e-108
NZ_CP053640.1\|WP_000927371.1\|2680918_2683051_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NZ_CP053640.1\|WP_001292149.1\|2680472_2680907_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NZ_CP053640.1\|WP_000003759.1\|2693417_2693738_-\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_CP053640.1\|WP_000123398.1\|2696861_2698235_+\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	4.11455e-06
NZ_CP053640.1\|WP_000019734.1\|2692438_2693416_-\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
NZ_CP053640.1\|WP_000083807.1\|2683085_2684624_-\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_CP053640.1\|WP_000648723.1\|2679366_2680473_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_CP053640.1\|WP_000908182.1\|2687341_2688124_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NZ_CP053640.1\|WP_000370923.1\|2688191_2689049_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	2.39536e-58
NZ_CP053640.1\|WP_001024095.1\|2693889_2694555_+\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NZ_CP053640.1\|WP_000334463.1\|2685304_2687110_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_CP053640.1\|WP_000070866.1\|2699304_2699748_+\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NZ_CP053640.1\|WP_001127960.1\|2694990_2695929_+\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129

>NZ_CP053640.1|WP_001802298.1|2690544_2690649_+|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NZ_CP053640.1|WP_001792784.1|2689706_2689865_-|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NZ_CP053640.1|WP_000370923.1|2688191_2689049_+|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTLDVTAYTNEEDGAAKYLAKHFLAD
>NZ_CP053640.1|WP_000908182.1|2687341_2688124_+|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_CP053640.1|WP_000334463.1|2685304_2687110_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_CP053640.1|WP_000083807.1|2683085_2684624_-|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_CP053640.1|WP_000927371.1|2680918_2683051_-|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_CP053640.1|WP_001292149.1|2680472_2680907_-|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_CP053640.1|WP_000648723.1|2679366_2680473_-|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_CP053640.1|WP_001048259.1|2671602_2679048_+|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQITSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE
>NZ_CP053640.1|WP_000495669.1|2691081_2692173_-|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENGKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NZ_CP053640.1|WP_000019734.1|2692438_2693416_-|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_CP053640.1|WP_000003759.1|2693417_2693738_-|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_CP053640.1|WP_001024095.1|2693889_2694555_+|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NZ_CP053640.1|WP_001127960.1|2694990_2695929_+|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_CP053640.1|WP_000808817.1|2695959_2696190_+|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_CP053640.1|WP_000123398.1|2696861_2698235_+|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVKKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_CP053640.1|WP_001123303.1|2698691_2699105_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_CP053640.1|WP_000070866.1|2699304_2699748_+|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_CP053640.1|WP_000160304.1|2699868_2700579_-|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE

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Crispr_ID: NZ_CP053640_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053640_10

2820240-2820321

Orphan

Consensus_repeat	Method
ACAATGCAAGTTGGGGTGGGGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053640_10

>merge|NZ_CP053640|10|2820240-2820321|CRISPRCasFinder
ACAATGCAAGTTGGGGTGGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAAACAATGTAAGTTGGGGTGGGGGCC

>NZ_CP053640|10|9|2820240-2820321|CRISPRCasFinder
ACAATGCAAGTTGGGGTGGGGGCC	CCAACACAGAGAATTTCGAAAAGAAATTCTACAA
ACAATGTAAGTTGGGGTGGGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053640.1\|WP_000109189.1\|2827685_2827871_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376389
NZ_CP053640.1\|WP_000791411.1\|2822200_2823256_+\|bi-component-leukocidin-LukGH-subunit-H	unknown	unknown	gnl\|CDD\|369625
NZ_CP053640.1\|WP_000345949.1\|2827867_2828014_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_001083975.1\|2828953_2829670_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225484
NZ_CP053640.1\|WP_000867951.1\|2812103_2812889_-\|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl\|CDD\|143607
NZ_CP053640.1\|WP_001549185.1\|2826640_2827354_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NZ_CP053640.1\|WP_000240642.1\|2816634_2818251_+\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NZ_CP053640.1\|WP_001105696.1\|2810570_2811134_-\|accessory-gene-regulator-ArgB-like-protein	unknown	unknown	gnl\|CDD\|226899
NZ_CP053640.1\|WP_000857200.1\|2825412_2826450_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP053640.1\|WP_000206625.1\|2820541_2821765_-\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|181490
NZ_CP053640.1\|WP_001094921.1\|2810424_2810568_-\|cyclic-lactone-autoinducer-peptide	unknown	unknown	gnl\|CDD\|129030
NZ_CP053640.1\|WP_000917289.1\|2816274_2816559_+\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NZ_CP053640.1\|WP_001549197.1\|2811369_2811504_+\|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|173213
NZ_CP053640.1\|WP_001557601.1\|2828087_2828942_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|214906
NZ_CP053640.1\|WP_001045079.1\|2818790_2820098_-\|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl\|CDD\|273349
NZ_CP053640.1\|WP_000705245.1\|2827432_2827615_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053640.1\|WP_000595392.1\|2823277_2824294_+\|bi-component-leukocidin-LukGH-subunit-G	unknown	unknown	gnl\|CDD\|369625
NZ_CP053640.1\|WP_000197635.1\|2815356_2816100_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP053640.1\|WP_000522381.1\|2813249_2813876_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|226090
NZ_CP053640.1\|WP_000120297.1\|2814072_2815332_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236768

Protein	Function_ID	Function_description	E-value
NZ_CP053640.1\|WP_000109189.1\|2827685_2827871_-\|hypothetical-protein	gnl\|CDD\|376389	pfam00815, Histidinol_dh, Histidinol dehydrogenase.	0.00485103
NZ_CP053640.1\|WP_000791411.1\|2822200_2823256_+\|bi-component-leukocidin-LukGH-subunit-H	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.84035e-77
NZ_CP053640.1\|WP_001083975.1\|2828953_2829670_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.83656e-21
NZ_CP053640.1\|WP_000867951.1\|2812103_2812889_-\|carbon-nitrogen-family-hydrolase	gnl\|CDD\|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	5.69545e-126
NZ_CP053640.1\|WP_001549185.1\|2826640_2827354_-\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	0.000176738
NZ_CP053640.1\|WP_000240642.1\|2816634_2818251_+\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_CP053640.1\|WP_001105696.1\|2810570_2811134_-\|accessory-gene-regulator-ArgB-like-protein	gnl\|CDD\|226899	COG4512, AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription].	6.65966e-71
NZ_CP053640.1\|WP_000857200.1\|2825412_2826450_-\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.96401e-25
NZ_CP053640.1\|WP_000206625.1\|2820541_2821765_-\|ArgE/DapE-family-deacylase	gnl\|CDD\|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NZ_CP053640.1\|WP_001094921.1\|2810424_2810568_-\|cyclic-lactone-autoinducer-peptide	gnl\|CDD\|129030	smart00794, AgrD, Staphylococcal AgrD protein. This family consists of several AgrD proteins from many Staphylococcus species. The agr locus was initially described in Staphylococcus aureus as an element controlling the production of exoproteins implicated in virulence. Its pattern of action has been shown to be complex, upregulating certain extracellular toxins and enzymes expressed post-exponentially and repressing some exponential-phase surface components. AgrD encodes the precursor of the autoinducing peptide (AIP).The AIP derived from AgrD by the action of AgrB interacts with AgrC in the membrane to activate AgrA, which upregulates transcription both from promoter P2, amplifying the response, and from P3, initiating the production of a novel effector: RNAIII. In S. aureus, delta-hemolysin is the only translation product of RNA III and is not involved in the regulatory functions of the transcript, which is therefore the primary agent for modulating the expression of other operons controlled by agr.	3.13559e-15
NZ_CP053640.1\|WP_000917289.1\|2816274_2816559_+\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NZ_CP053640.1\|WP_001549197.1\|2811369_2811504_+\|delta-lysin-family-phenol-soluble-modulin	gnl\|CDD\|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NZ_CP053640.1\|WP_001557601.1\|2828087_2828942_-\|restriction-endonuclease	gnl\|CDD\|214906	smart00910, HIRAN, The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, such as a nuclease of the restriction endonuclease fold and TDP1-like DNA phosphoesterases, in the eukaryotes. It has been predicted that this protein functions as a DNA-binding domain that probably recognises features associated with damaged DNA or stalled replication forks.	5.87951e-12
NZ_CP053640.1\|WP_001045079.1\|2818790_2820098_-\|TrkH-family-potassium-uptake-protein	gnl\|CDD\|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	7.96864e-82
NZ_CP053640.1\|WP_000595392.1\|2823277_2824294_+\|bi-component-leukocidin-LukGH-subunit-G	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.05827e-99
NZ_CP053640.1\|WP_000197635.1\|2815356_2816100_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NZ_CP053640.1\|WP_000522381.1\|2813249_2813876_-\|nitroreductase-family-protein	gnl\|CDD\|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.42197e-117
NZ_CP053640.1\|WP_000120297.1\|2814072_2815332_+\|hypothetical-protein	gnl\|CDD\|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	6.51148e-10

>NZ_CP053640.1|WP_001045079.1|2818790_2820098_-|TrkH-family-potassium-uptake-protein
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NZ_CP053640.1|WP_000240642.1|2816634_2818251_+|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NZ_CP053640.1|WP_000917289.1|2816274_2816559_+|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NZ_CP053640.1|WP_000197635.1|2815356_2816100_-|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NZ_CP053640.1|WP_000120297.1|2814072_2815332_+|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NZ_CP053640.1|WP_000522381.1|2813249_2813876_-|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NZ_CP053640.1|WP_000867951.1|2812103_2812889_-|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NZ_CP053640.1|WP_001549197.1|2811369_2811504_+|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NZ_CP053640.1|WP_001105696.1|2810570_2811134_-|accessory-gene-regulator-ArgB-like-protein
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED
>NZ_CP053640.1|WP_001094921.1|2810424_2810568_-|cyclic-lactone-autoinducer-peptide
MNTLVNMFFDFIIKLAKAIGIVGGVNACSSLFDEPKVPAELTNLYDK
>NZ_CP053640.1|WP_000206625.1|2820541_2821765_-|ArgE/DapE-family-deacylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>NZ_CP053640.1|WP_000791411.1|2822200_2823256_+|bi-component-leukocidin-LukGH-subunit-H
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NZ_CP053640.1|WP_000595392.1|2823277_2824294_+|bi-component-leukocidin-LukGH-subunit-G
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NZ_CP053640.1|WP_000857200.1|2825412_2826450_-|site-specific-integrase
MKTRCYDGKKWQYEFKYEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDYSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>NZ_CP053640.1|WP_001549185.1|2826640_2827354_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MTHNIEKRINKLKTSGNPKFKKLDSDIHYLLKRFEGEKNHKGFYPKFKQGEIVFVDFGINVNKEFSNSHFAIVMNKNDSNTEDIVNVIPLSSKENKKYLKMNFDLKWEYYLRLFLNLISAQNNSAILKEVFDKKYQKNNTEFITKDYFSEFISDSLEIENKLNKIDRNINNIVSAIDKVKKLKGNSYACINSFQPISKFRIRKVLPQKIKNPVIDSSDIMLLINRINNNILQIPDIR
>NZ_CP053640.1|WP_000705245.1|2827432_2827615_-|hypothetical-protein
MKITNCKIKRETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKIDGDKLTKEDSL
>NZ_CP053640.1|WP_000109189.1|2827685_2827871_-|hypothetical-protein
MSTYKEIEHLHINTGGKELTQEQIEEAKAFIDSQEFKDMIREAKESHQRVMESKITDRTKL
>NZ_CP053640.1|WP_000345949.1|2827867_2828014_-|hypothetical-protein
MDFKEVDINIEEWEMVEIPFYTEEELTYRLNNGLPITKSELEEQESKK
>NZ_CP053640.1|WP_001557601.1|2828087_2828942_-|restriction-endonuclease
MKPRKQDEKILSDQYSYFEPIISDSCDIKFDENKRRMGSIFISHEEICFIRKEEDYIFKISLSEVIDYNTVVTIWKNQAFLTLNDNRKLTVYFVTNSPLTGFISILKTYMQLSKNKETIISNDCLPINDDEQTKVEIFDVVGLNYEGRRKELKKLIKKMKNNDDFFFLYSDLKGNELKEELLYEDKVYEISDYEVIPGVFLQKEPDNPYDENAIKVMISNEYSEFHVGYVPREYASRLVNHMDNIVSCNAYINGGKYKTLDYLEEKIVTKESDYGLRVHLEYKV
>NZ_CP053640.1|WP_001083975.1|2828953_2829670_-|helix-turn-helix-domain-containing-protein
MNSFKDRLKQIMSERKISQSELSRRTGIGRNSISDYLNGKYEAKQDKVFELAKALNVNEAWLMGFDISKNRKIENNDITSIYSKLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNGDSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLYFYDNESVRLVGKVIL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP053640_10	10.1\|2820264\|34\|NZ_CP053640\|CRISPRCasFinder	2820264-2820297	34	NZ_CP053640.1	982076-982109	0	1.0
NZ_CP053640_10	10.1\|2820264\|34\|NZ_CP053640\|CRISPRCasFinder	2820264-2820297	34	NZ_CP053640.1	1295569-1295602	0	1.0
NZ_CP053640_1	1.1\|454691\|33\|NZ_CP053640\|CRISPRCasFinder	454691-454723	33	NZ_CP053640.1	770330-770362	1	0.97
NZ_CP053640_1	1.1\|454691\|33\|NZ_CP053640\|CRISPRCasFinder	454691-454723	33	NZ_CP053640.1	1290011-1290043	1	0.97
NZ_CP053640_2	2.1\|1246807\|34\|NZ_CP053640\|CRISPRCasFinder	1246807-1246840	34	NZ_CP053640.1	770330-770363	1	0.971
NZ_CP053640_3	3.1\|1295547\|31\|NZ_CP053640\|CRISPRCasFinder	1295547-1295577	31	NZ_CP053640.1	420236-420266	1	0.968
NZ_CP053640_6	6.1\|2405937\|33\|NZ_CP053640\|CRISPRCasFinder	2405937-2405969	33	NZ_CP053640.1	1246494-1246526	1	0.97
NZ_CP053640_6	6.1\|2405937\|33\|NZ_CP053640\|CRISPRCasFinder	2405937-2405969	33	NZ_CP053640.1	1282712-1282744	1	0.97
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1282772-1282802	1	0.968
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1282828-1282858	1	0.968
NZ_CP053640_10	10.1\|2820264\|34\|NZ_CP053640\|CRISPRCasFinder	2820264-2820297	34	NZ_CP053640.1	328006-328039	1	0.971
NZ_CP053640_5	5.1\|2330768\|46\|NZ_CP053640\|PILER-CR	2330768-2330813	46	NZ_CP053640.1	2327202-2327247	2	0.957
NZ_CP053640_5	5.2\|2330831\|37\|NZ_CP053640\|PILER-CR	2330831-2330867	37	NZ_CP053640.1	2327265-2327301	2	0.946
NZ_CP053640_6	6.1\|2405937\|33\|NZ_CP053640\|CRISPRCasFinder	2405937-2405969	33	NZ_CP053640.1	2796222-2796254	2	0.939
NZ_CP053640_6	6.1\|2405937\|33\|NZ_CP053640\|CRISPRCasFinder	2405937-2405969	33	NZ_CP053640.1	1282768-1282800	2	0.939
NZ_CP053640_6	6.1\|2405937\|33\|NZ_CP053640\|CRISPRCasFinder	2405937-2405969	33	NZ_CP053640.1	1282824-1282856	2	0.939
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	440055-440085	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	770374-770404	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	976475-976505	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1463454-1463484	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1730509-1730539	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	79220-79250	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	681825-681855	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	681941-681971	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1080526-1080556	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1246442-1246472	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1246498-1246528	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	1282716-1282746	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	2025372-2025402	2	0.935
NZ_CP053640_7	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	NZ_CP053640.1	2581453-2581483	2	0.935
NZ_CP053640_10	10.1\|2820264\|34\|NZ_CP053640\|CRISPRCasFinder	2820264-2820297	34	NZ_CP053640.1	765956-765989	2	0.941
NZ_CP053640_10	10.1\|2820264\|34\|NZ_CP053640\|CRISPRCasFinder	2820264-2820297	34	NZ_CP053640.1	2132421-2132454	2	0.941

1. spacer 10.1|2820264|34|NZ_CP053640|CRISPRCasFinder matches to position: 982076-982109, mismatch: 0, identity: 1.0

ccaacacagagaatttcgaaaagaaattctacaa	CRISPR spacer
ccaacacagagaatttcgaaaagaaattctacaa	Protospacer
**********************************

2. spacer 10.1|2820264|34|NZ_CP053640|CRISPRCasFinder matches to position: 1295569-1295602, mismatch: 0, identity: 1.0

ccaacacagagaatttcgaaaagaaattctacaa	CRISPR spacer
ccaacacagagaatttcgaaaagaaattctacaa	Protospacer
**********************************

3. spacer 1.1|454691|33|NZ_CP053640|CRISPRCasFinder matches to position: 770330-770362, mismatch: 1, identity: 0.97

tgggccccaacacagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
************ ********************

4. spacer 1.1|454691|33|NZ_CP053640|CRISPRCasFinder matches to position: 1290011-1290043, mismatch: 1, identity: 0.97

tgggccccaacacagagaaattggattcccaat	CRISPR spacer
tgggccccaacacagagaaattggatttccaat	Protospacer
***************************.*****

5. spacer 2.1|1246807|34|NZ_CP053640|CRISPRCasFinder matches to position: 770330-770363, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattctcaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
*****************************.****

6. spacer 3.1|1295547|31|NZ_CP053640|CRISPRCasFinder matches to position: 420236-420266, mismatch: 1, identity: 0.968

ggcaatgcaagttggcggggccccaacacag	CRISPR spacer
ggcaatggaagttggcggggccccaacacag	Protospacer
******* ***********************

7. spacer 6.1|2405937|33|NZ_CP053640|CRISPRCasFinder matches to position: 1246494-1246526, mismatch: 1, identity: 0.97

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaagctggcggaaagtcagcttacaataatg	Protospacer
*** *****************************

8. spacer 6.1|2405937|33|NZ_CP053640|CRISPRCasFinder matches to position: 1282712-1282744, mismatch: 1, identity: 0.97

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaagctggcggaaagtcagcttacaataatg	Protospacer
*** *****************************

9. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1282772-1282802, mismatch: 1, identity: 0.968

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacggaaagtcagcttacaataatgtg	Protospacer
*******.***********************

10. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1282828-1282858, mismatch: 1, identity: 0.968

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacggaaagtcagcttacaataatgtg	Protospacer
*******.***********************

11. spacer 10.1|2820264|34|NZ_CP053640|CRISPRCasFinder matches to position: 328006-328039, mismatch: 1, identity: 0.971

ccaacacagagaatttcgaaaagaaattctacaa	CRISPR spacer
ccaacacaaagaatttcgaaaagaaattctacaa	Protospacer
********.*************************

12. spacer 5.1|2330768|46|NZ_CP053640|PILER-CR matches to position: 2327202-2327247, mismatch: 2, identity: 0.957

acaaagataaacctaattatcaatttggtggacacaacagtgttga	CRISPR spacer
acaaagataaacctaattatcaattcggtggacacaatagtgttga	Protospacer
*************************.***********.********

13. spacer 5.2|2330831|37|NZ_CP053640|PILER-CR matches to position: 2327265-2327301, mismatch: 2, identity: 0.946

ttccaaaagtaagtggtcaaaatgaaggtcaacaaac	CRISPR spacer
ttccaaaagtaagcggccaaaatgaaggtcaacaaac	Protospacer
*************.**.********************

14. spacer 6.1|2405937|33|NZ_CP053640|CRISPRCasFinder matches to position: 2796222-2796254, mismatch: 2, identity: 0.939

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaggctggcggaaagtcagcttacaataatg	Protospacer
*** .****************************

15. spacer 6.1|2405937|33|NZ_CP053640|CRISPRCasFinder matches to position: 1282768-1282800, mismatch: 2, identity: 0.939

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaagctgacggaaagtcagcttacaataatg	Protospacer
*** *****.***********************

16. spacer 6.1|2405937|33|NZ_CP053640|CRISPRCasFinder matches to position: 1282824-1282856, mismatch: 2, identity: 0.939

cagtagctggcggaaagtcagcttacaataatg	CRISPR spacer
cagaagctgacggaaagtcagcttacaataatg	Protospacer
*** *****.***********************

17. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 440055-440085, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctggcggaaagtcagcttacaataatgtg	Protospacer
*****.*.***********************

18. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 770374-770404, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

19. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 976475-976505, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

20. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1463454-1463484, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

21. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1730509-1730539, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

22. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 79220-79250, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

23. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 681825-681855, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

24. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 681941-681971, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

25. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1080526-1080556, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

26. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1246442-1246472, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

27. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1246498-1246528, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctggcggaaagtcagcttacaataatgtg	Protospacer
*****.*.***********************

28. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 1282716-1282746, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctggcggaaagtcagcttacaataatgtg	Protospacer
*****.*.***********************

29. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 2025372-2025402, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctggcggaaagtcagcttacaataatgtg	Protospacer
*****.*.***********************

30. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to position: 2581453-2581483, mismatch: 2, identity: 0.935

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

31. spacer 10.1|2820264|34|NZ_CP053640|CRISPRCasFinder matches to position: 765956-765989, mismatch: 2, identity: 0.941

ccaacacagagaatttcgaaaagaaattctacaa	CRISPR spacer
ccaacacagagaatttcgataagaaattccacaa	Protospacer
******************* *********.****

32. spacer 10.1|2820264|34|NZ_CP053640|CRISPRCasFinder matches to position: 2132421-2132454, mismatch: 2, identity: 0.941

ccaacacagagaatttcgaaaagaaattctacaa	CRISPR spacer
ccaacaaaaagaatttcgaaaagaaattctacaa	Protospacer
****** *.*************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053640_8	8.1\|2678685\|34\|NZ_CP053640\|CRISPRCasFinder	2678685-2678718	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NZ_CP053640_8	8.1\|2678685\|34\|NZ_CP053640\|CRISPRCasFinder	2678685-2678718	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765
NZ_CP053640_9	9.1\|2691009\|32\|NZ_CP053640\|CRISPRCasFinder	2691009-2691040	32	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	41454-41485	9	0.719
NZ_CP053640_9	9.1\|2691009\|32\|NZ_CP053640\|CRISPRCasFinder	2691009-2691040	32	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	296489-296520	10	0.688

1. spacer 8.1|2678685|34|NZ_CP053640|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

cccagttgcaaacaataaagctaaagatatgcaa	CRISPR spacer
agcatataaaagctataaagctaaagatatgcaa	Protospacer
  **  *. **.* ********************

2. spacer 8.1|2678685|34|NZ_CP053640|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

cccagttgcaaacaataaagctaaagatatgcaa	CRISPR spacer
tactgtttataacaataaagctaaagttattcaa	Protospacer
. * ***   **************** *** ***

3. spacer 9.1|2691009|32|NZ_CP053640|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 9, identity: 0.719

aaaagtaggagcgcctgcgctaagcgcatgca	CRISPR spacer
tggaggtggagcgcctgcgcaaggcgcatgag	Protospacer
 ..**  ************* *.******* .

4. spacer 9.1|2691009|32|NZ_CP053640|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

aaaagtaggagcgcctgcgctaagcgcatgca	CRISPR spacer
tcgaagccgagcgcctgcgcgtagcgcatgcg	Protospacer
  .*.   ************  *********.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 24267

Staphylococcus_phage(96.15%)

head,protease,holin,tail,capsid,terminase,portal

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625096.1\|0_1662_+\|terminase	terminase large subunit	A0A075M4D3	Staphylococcus_phage	0.0e+00	100.0
WP_000025268.1\|1677_2841_+\|portal	phage portal protein	A0A1W6JPQ9	Staphylococcus_phage	1.8e-216	100.0
WP_000861911.1\|2824_3562_+\|protease	Clp protease ClpP	A0A1W6JPK0	Staphylococcus_phage	1.8e-129	100.0
WP_000154568.1\|3584_4730_+\|capsid	phage major capsid protein	A0A1W6JPL4	Staphylococcus_phage	7.3e-215	99.7
WP_000238241.1\|4749_5034_+	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	5.2e-45	97.9
WP_000150936.1\|5023_5308_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000755150.1\|5291_5654_+\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000114341.1\|5650_6055_+	HK97 gp10 family phage protein	A0A1W6JPJ1	Staphylococcus_phage	2.5e-69	100.0
WP_000565498.1\|6051_6459_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000985142.1\|6459_7104_+\|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	1.9e-119	99.1
WP_071621395.1\|7145_7370_+	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_001096355.1\|7419_7770_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_001557459.1\|8014_12547_+\|tail	phage tail tape measure protein	A0EX03	Staphylococcus_phage	0.0e+00	98.9
WP_000567396.1\|12543_14028_+\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	4.5e-297	99.8
WP_000582154.1\|14043_17829_+	hypothetical protein	Q6R866	Staphylococcus_virus	0.0e+00	98.3
WP_001153681.1\|17818_17971_+	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_001040261.1\|18017_18305_+	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_000539688.1\|18362_18659_+	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_011447039.1\|18808_18985_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_001791821.1\|19037_19145_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|19196_19451_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|19462_20218_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000919350.1\|20408_20900_+	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_000727649.1\|21979_22429_-	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_000702263.1\|23113_23464_+	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|23516_23777_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000669789.1\|24087_24267_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0

DBSCAN-SWA_2

29878 : 32325

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000991306.1\|29878_30775_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	5.0e-17	30.2
WP_000645727.1\|30775_31456_+	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000763043.1\|31452_32325_+	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	1.0e-27	36.0

DBSCAN-SWA_3

38089 : 38491

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000205106.1\|38089_38491_-	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9

DBSCAN-SWA_4

42687 : 44714

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000149686.1\|42687_43248_-	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_173896704.1\|43616_44714_+	pectate lyase	U5PWM6	Bacillus_phage	1.9e-47	34.6

DBSCAN-SWA_5

48744 : 51028

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000284436.1\|48744_50214_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	5.9e-108	45.1
WP_000040866.1\|50206_51028_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7

DBSCAN-SWA_6

54729 : 61496

Gordonia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000572878.1\|54729_56025_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_001165363.1\|56133_56436_+	hypothetical protein	NA	NA	NA	NA
WP_000272056.1\|56607_57300_+	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_000992924.1\|57296_59489_+	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000774556.1\|59492_61496_+	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.2e-114	36.2

DBSCAN-SWA_7

68670 : 73699

Catovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173896708.1\|68670_69618_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	1.5e-16	27.8
WP_001147865.1\|69698_71060_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A1X9I6F4	Streptococcus_phage	1.4e-103	43.6
WP_000548781.1\|71229_71760_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_000140172.1\|72006_73077_+	DNA polymerase IV	NA	NA	NA	NA
WP_000613738.1\|73144_73699_-	3'-5' exonuclease	B5WZL1	Staphylococcus_phage	1.2e-29	35.7

DBSCAN-SWA_8

77151 : 77565

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001557448.1\|77151_77565_+	hypothetical protein	A0A1Q1PVU5	Staphylococcus_phage	6.7e-17	38.3

DBSCAN-SWA_9

82619 : 83249

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000153535.1\|82619_83249_+	two-component system response regulator VraR	W8CYM9	Bacillus_phage	8.1e-06	30.8

DBSCAN-SWA_10

89278 : 166014

Staphylococcus_phage(75.71%)

tRNA,head,plate,transposase,holin,tail,integrase,capsid,terminase,portal

attL 85798:85815|attR 121238:121255

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
85798:85815	attL	NA	NA	NA	NA
WP_001145723.1\|89278_90325_-\|integrase	site-specific integrase	Q4ZB10	Staphylococcus_virus	2.3e-199	99.1
WP_000392109.1\|90535_91216_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A2H4PQQ5	Staphylococcus_phage	5.1e-123	100.0
WP_000705238.1\|91355_91523_-	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
WP_173896710.1\|91592_92363_-	helix-turn-helix domain-containing protein	A0A1X9H0P5	Staphylococcus_phage	6.4e-138	97.7
WP_000338187.1\|92522_92744_+	DUF739 family protein	A0A1X9H090	Staphylococcus_phage	7.6e-36	100.0
WP_000435360.1\|92767_93211_+	hypothetical protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
WP_000939495.1\|93225_93366_+	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
WP_000772137.1\|93358_93568_-	hypothetical protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
WP_001148338.1\|93624_94374_+	phage antirepressor KilAC domain-containing protein	B7T097	Staphylococcus_virus	3.4e-136	99.6
WP_001148568.1\|94389_95178_+	phage antirepressor KilAC domain-containing protein	R9QSV3	Staphylococcus_phage	3.6e-144	99.6
WP_016528750.1\|95193_95397_+	hypothetical protein	A0A0E3XBM9	Staphylococcus_phage	5.2e-31	98.5
WP_000395455.1\|95734_95965_-	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
WP_000594789.1\|96035_96257_+	hypothetical protein	B2ZYU8	Staphylococcus_phage	8.7e-32	100.0
WP_000066011.1\|96249_96411_+	DUF1270 domain-containing protein	Q4ZAZ7	Staphylococcus_virus	2.5e-20	100.0
WP_000291089.1\|96507_96768_+	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
WP_000815400.1\|96777_96999_+	DUF2483 family protein	A0A2H4PQR5	Staphylococcus_phage	4.2e-34	100.0
WP_070856932.1\|96991_97771_+	ATP-binding protein	Q9G028	Staphylococcus_virus	2.8e-141	99.2
WP_000704713.1\|97800_98355_+	single-stranded DNA-binding protein	A7TWM8	Staphylococcus_phage	1.0e-100	100.0
WP_061389143.1\|98367_99039_+	hypothetical protein	Q9G025	Staphylococcus_virus	1.1e-125	97.8
WP_000132054.1\|99031_99745_+	helix-turn-helix domain-containing protein	A0A1J0MGB2	Staphylococcus_phage	9.2e-91	79.3
WP_064134395.1\|99754_100534_+	ATP-binding protein	A7YGR0	Staphylococcus_virus	2.7e-144	98.8
WP_000237154.1\|100527_100689_+	hypothetical protein	A0A0H4IU12	Staphylococcus_phage	1.0e-21	100.0
WP_001123688.1\|100701_100923_+	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_173896712.1\|100932_101340_+	RusA family crossover junction endodeoxyribonuclease	A9CR74	Staphylococcus_phage	3.8e-73	99.3
WP_001187259.1\|101339_101525_+	DUF3113 family protein	A0A1X9H053	Staphylococcus_phage	3.5e-26	95.1
WP_000907341.1\|101525_102143_+	hypothetical protein	A0A0H3U4U9	Staphylococcus_phage	1.2e-83	99.5
WP_000022722.1\|102142_102397_+	DUF3310 domain-containing protein	A0A2K9VBW1	Staphylococcus_phage	1.6e-42	100.0
WP_001802342.1\|102396_102645_+	hypothetical protein	A0A2I6PDB4	Staphylococcus_phage	1.3e-39	95.1
WP_000693989.1\|102658_102865_+	hypothetical protein	A0A2K9VBT9	Staphylococcus_phage	3.0e-34	100.0
WP_000695753.1\|102867_103272_+	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	1.0e-70	98.5
WP_173896714.1\|103268_103616_+	hypothetical protein	D2JGL4	Staphylococcus_phage	1.7e-58	99.1
WP_000144703.1\|103612_103921_+	hypothetical protein	Q6R826	Staphylococcus_virus	8.4e-49	96.1
WP_173896715.1\|103913_104162_+	DUF1024 family protein	Q9B0F3	Staphylococcus_virus	7.7e-37	96.3
WP_000185653.1\|104154_104685_+	dUTP pyrophosphatase	C8CH05	Staphylococcus_phage	1.7e-94	100.0
WP_000195803.1\|104721_104928_+	DUF1381 domain-containing protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
WP_173896717.1\|104924_105308_+	hypothetical protein	A0A0H3U465	Staphylococcus_phage	8.2e-62	97.6
WP_000595244.1\|105307_105481_+	transcriptional activator RinB	S4SVE4	Staphylococcus_phage	6.4e-22	100.0
WP_000286968.1\|105481_105883_+	hypothetical protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
WP_000594087.1\|106235_106730_+\|terminase	terminase small subunit	A0A0N9BAX3	Staphylococcus_phage	2.2e-83	99.4
WP_001037578.1\|106722_107946_+\|terminase	PBSX family phage terminase large subunit	A0A0N9BAX9	Staphylococcus_phage	7.5e-242	100.0
WP_173896719.1\|107942_109367_+\|portal	phage portal protein	Q4ZBZ7	Staphylococcus_virus	1.3e-269	99.4
WP_000184133.1\|109335_110289_+\|head	phage head morphogenesis protein	A0A0N7E0U6	Staphylococcus_phage	6.6e-177	99.7
WP_000346033.1\|110290_110497_+	hypothetical protein	A0A0N9BB04	Staphylococcus_phage	3.2e-28	100.0
WP_001019219.1\|110599_111184_+	DUF4355 domain-containing protein	A0A0N7E0U8	Staphylococcus_phage	1.3e-77	100.0
WP_000235168.1\|111200_112115_+\|capsid	phage major capsid protein	A0A0H3U2U7	Staphylococcus_phage	1.2e-170	100.0
WP_000002931.1\|112126_112270_+	hypothetical protein	A0A0E3XC49	Staphylococcus_phage	4.6e-18	100.0
WP_016528745.1\|112275_112626_+\|head,tail	phage gp6-like head-tail connector family protein	A0A0H3U2R5	Staphylococcus_phage	4.1e-60	99.1
WP_000483041.1\|112637_112973_+\|head	phage head closure protein	A0A0E3TAH8	Staphylococcus_phage	8.8e-60	100.0
WP_001151330.1\|112959_113373_+	HK97 gp10 family phage protein	A0A0N9BAY5	Staphylococcus_phage	1.1e-75	100.0
WP_000270192.1\|113385_113811_+	DUF3168 domain-containing protein	Q4ZBQ9	Staphylococcus_phage	5.5e-75	100.0
WP_000057582.1\|113811_114369_+\|tail	tail protein	Q4ZBQ8	Staphylococcus_phage	8.2e-103	100.0
WP_000134337.1\|114435_114942_+	hypothetical protein	Q4ZBQ7	Staphylococcus_phage	2.7e-92	100.0
WP_000880587.1\|114986_115271_+	hypothetical protein	A0A0N7E0V9	Staphylococcus_phage	8.8e-45	100.0
WP_016528744.1\|115274_118418_+	hypothetical protein	Q4ZBY3	Staphylococcus_virus	0.0e+00	100.0
WP_000560181.1\|118432_119374_+\|tail	phage tail family protein	Q4ZBQ4	Staphylococcus_phage	5.2e-182	100.0
WP_001122001.1\|119384_121271_+\|tail	phage tail protein	Q4ZBQ3	Staphylococcus_phage	0.0e+00	100.0
121238:121255	attR	NA	NA	NA	NA
WP_031833105.1\|121283_123182_+	hypothetical protein	A0A0H3U448	Staphylococcus_phage	0.0e+00	97.3
WP_016528742.1\|123181_125005_+\|plate	phage baseplate upper protein	W5R8J5	Staphylococcus_phage	8.2e-277	95.2
WP_000705914.1\|125004_125382_+	DUF2977 domain-containing protein	W5R9M2	Staphylococcus_phage	3.4e-60	99.2
WP_001790193.1\|125385_125559_+	XkdX family protein	Q8LTH6	Staphylococcus_phage	1.7e-27	100.0
WP_000466769.1\|125599_125899_+	DUF2951 domain-containing protein	Q4ZBP8	Staphylococcus_phage	1.3e-46	100.0
WP_000524040.1\|126035_127910_+	glucosaminidase domain-containing protein	Q4ZBX1	Staphylococcus_virus	0.0e+00	100.0
WP_000276647.1\|127922_129095_+\|plate	BppU family phage baseplate upper protein	A0EWU8	Staphylococcus_virus	4.1e-197	100.0
WP_000398862.1\|129100_129496_+	hypothetical protein	Q4ZBW9	Staphylococcus_virus	1.6e-68	100.0
WP_000354132.1\|129551_129989_+\|holin	phage holin	A0A2H4PQP0	Staphylococcus_phage	4.1e-73	100.0
WP_016528741.1\|129969_131415_+	SH3 domain-containing protein	Q4ZAM7	Staphylococcus_virus	8.5e-293	99.0
WP_000344116.1\|131811_132123_+	DUF3467 domain-containing protein	A0A2H4PQQ9	Staphylococcus_phage	4.1e-51	100.0
WP_001251276.1\|132109_132493_+	hypothetical protein	A0A2H4PQP6	Staphylococcus_phage	6.1e-65	99.2
WP_106875183.1\|132589_132670_-	hypothetical protein	NA	NA	NA	NA
WP_001005407.1\|133016_133178_+	hypothetical protein	NA	NA	NA	NA
WP_000163283.1\|133308_133824_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_000830384.1\|134163_134973_+	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_001124422.1\|135232_136051_+	recombination regulator RecX	NA	NA	NA	NA
WP_000435806.1\|136028_136343_+	YfhH family protein	NA	NA	NA	NA
WP_000535834.1\|136357_137875_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000886462.1\|137883_138720_+	membrane protein	NA	NA	NA	NA
WP_001557163.1\|139093_140413_+\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000379098.1\|140500_141478_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_000284765.1\|141629_142667_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_000251253.1\|142969_143512_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000597238.1\|143802_145539_+	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	1.7e-53	30.4
WP_001236371.1\|145728_146823_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_001011595.1\|147115_148405_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_000939528.1\|148485_148941_+	thioredoxin-dependent thiol peroxidase	NA	NA	NA	NA
WP_000869447.1\|148946_149897_+	2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_000110007.1\|149993_150440_+	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_001557163.1\|158866_160186_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000063582.1\|160769_161831_+	PTS transporter subunit IIC	NA	NA	NA	NA
WP_000649915.1\|162088_163546_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_000590809.1\|163538_164261_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	42.7
WP_000379980.1\|164411_165539_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_000181395.1\|165543_166014_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA

DBSCAN-SWA_11

174858 : 175203

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000290301.1\|174858_175203_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7

DBSCAN-SWA_12

184833 : 185574

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000216874.1\|184833_185574_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-24	29.8

DBSCAN-SWA_13

193358 : 197623

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010922839.1\|193358_194141_+	staphylococcal enterotoxin type O	A0A1X9H080	Staphylococcus_phage	1.1e-31	36.7
WP_000821658.1\|194421_195141_+	staphylococcal enterotoxin type M	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
WP_000713847.1\|195175_195904_+	staphylococcal enterotoxin type I	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
WP_001236362.1\|196867_197623_+	staphylococcal enterotoxin type N	A0A075M4C7	Staphylococcus_phage	6.0e-40	41.4

DBSCAN-SWA_14

201672 : 267418

Staphylococcus_phage(95.65%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000206343.1\|201672_202461_-	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	3.6e-144	98.5
WP_000878802.1\|203838_204759_+	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	2.3e-174	100.0
WP_000782463.1\|204760_205744_+	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
WP_000543854.1\|206113_206905_-	DUF1828 domain-containing protein	NA	NA	NA	NA
WP_000550252.1\|206909_207383_-	hypothetical protein	NA	NA	NA	NA
WP_001092780.1\|208329_208911_-	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8
WP_001039427.1\|209874_210582_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
WP_001039454.1\|210706_211429_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
WP_001038872.1\|211486_212206_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001038704.1\|212326_213046_+\|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_011447030.1\|212994_213102_-	hypothetical protein	NA	NA	NA	NA
WP_001791797.1\|213985_214120_+	hypothetical protein	NA	NA	NA	NA
WP_000028669.1\|214283_215840_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
WP_000072627.1\|215832_217062_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	4.0e-134	64.7
WP_001792025.1\|218137_218239_-	hypothetical protein	NA	NA	NA	NA
WP_001801861.1\|218361_218457_-	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_000414216.1\|219811_220384_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
WP_000627540.1\|220484_220826_-	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
WP_000669024.1\|220866_221493_-	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
WP_000070642.1\|221567_222563_-	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
WP_001795210.1\|222643_223294_-	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.9e-51	94.0
WP_012840523.1\|223597_224053_+	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
WP_000348364.1\|224211_225690_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.8e-283	97.6
WP_000778528.1\|225694_226696_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
WP_000718107.1\|226692_226950_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000672013.1\|227015_227489_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_001822900.1\|227493_228240_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000109906.1\|228617_230210_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_000933820.1\|230581_231778_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000366163.1\|231899_232808_+	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000453306.1\|233019_233853_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
WP_000623470.1\|235849_236203_-	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
WP_001200542.1\|236199_236565_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000091442.1\|236820_237123_-	hypothetical protein	NA	NA	NA	NA
WP_001096494.1\|237382_238096_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_001168903.1\|238535_239171_-\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001030469.1\|239466_239910_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001153742.1\|239896_240340_-	competence protein ComK	NA	NA	NA	NA
WP_000671057.1\|240452_240923_-	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	8.8e-82	98.1
WP_000384171.1\|241121_241346_+	hypothetical protein	NA	NA	NA	NA
WP_001032833.1\|241621_242476_+	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000989121.1\|242562_243855_-	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_000221177.1\|243854_244169_-	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_001261668.1\|244691_246194_+	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000077358.1\|246674_247718_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
WP_000493887.1\|247724_248357_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
WP_001159037.1\|248367_249549_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
WP_001008549.1\|249561_250026_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001196362.1\|250147_251149_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
WP_001790712.1\|251259_251379_+	hypothetical protein	NA	NA	NA	NA
WP_000266096.1\|251381_252209_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_000757543.1\|252780_253182_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000764419.1\|253304_253868_-	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000526539.1\|253864_254818_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_001025067.1\|254927_256109_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_001557386.1\|256396_258814_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_000836461.1\|258835_259147_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
WP_001050568.1\|259472_266033_+	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	6.1e-306	98.3
WP_000285020.1\|266149_267418_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	9.1e-57	99.1

DBSCAN-SWA_15

278709 : 284037

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001091387.1\|278709_279567_+	DUF1444 domain-containing protein	A0A2H4PQY3	Staphylococcus_phage	6.8e-72	100.0
WP_001048368.1\|279595_280192_+	DUF4479 domain-containing protein	NA	NA	NA	NA
WP_000118314.1\|280212_284037_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.6e-83	47.0

DBSCAN-SWA_16

292777 : 294484

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000862096.1\|292777_294484_+	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	8.0e-274	99.6

DBSCAN-SWA_17

301087 : 303718

Cronobacter_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000186029.1\|301087_302350_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	2.7e-85	42.1
WP_001279338.1\|302443_303718_-	trypsin-like peptidase domain-containing protein	A0A1B1IRD3	uncultured_Mediterranean_phage	1.7e-10	29.0

DBSCAN-SWA_18

307487 : 311620

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000808849.1\|307487_309092_-	phosphoglycerate dehydrogenase	A0A2H4PQU8	Staphylococcus_phage	1.2e-114	100.0
WP_000291420.1\|309078_310236_-	alanine--glyoxylate aminotransferase family protein	NA	NA	NA	NA
WP_000553924.1\|310350_310797_-	OsmC family protein	NA	NA	NA	NA
WP_000174280.1\|310876_311620_+	glycerophosphoryl diester phosphodiesterase	M1HTS7	Paramecium_bursaria_Chlorella_virus	4.9e-18	30.0

DBSCAN-SWA_19

329212 : 332410

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000226919.1\|329212_332410_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	4.2e-135	30.5

DBSCAN-SWA_20

337343 : 339101

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001232648.1\|337343_339101_+	pyruvate kinase	A0A2H4PQU5	Staphylococcus_phage	2.6e-41	100.0

DBSCAN-SWA_21

343985 : 352149

Feldmannia_irregularis_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080028.1\|343985_344690_+	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	1.6e-07	28.7
WP_015445861.1\|344689_346351_+	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	5.8e-35	39.4
WP_000849428.1\|346849_348337_+	hypothetical protein	NA	NA	NA	NA
WP_001038317.1\|348630_351261_+	DNA polymerase I	A8E2B3	Enterococcus_phage	6.1e-47	33.0
WP_001114454.1\|351276_352149_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	2.6e-42	39.1

DBSCAN-SWA_22

356064 : 367217

Brevibacillus_phage(20.0%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000808621.1\|356064_356985_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	8.1e-31	29.4
WP_001790562.1\|357077_357200_+	hypothetical protein	NA	NA	NA	NA
WP_000435132.1\|357397_359335_+\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	7.8e-116	36.0
WP_000049145.1\|359760_361254_+	amino acid permease	NA	NA	NA	NA
WP_001791162.1\|361482_362010_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	4.1e-11	33.1
WP_001125540.1\|362038_362239_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_001138360.1\|362285_362642_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_000032657.1\|362783_363392_+	NUDIX domain-containing protein	A0A060AB76	Staphylococcus_phage	6.6e-21	35.9
WP_001280022.1\|363410_364340_+	hypothetical protein	NA	NA	NA	NA
WP_001790560.1\|364344_364455_+	hypothetical protein	NA	NA	NA	NA
WP_000127573.1\|364502_365804_+	trigger factor	NA	NA	NA	NA
WP_000472302.1\|365954_367217_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.0e-140	62.0

DBSCAN-SWA_23

376784 : 383431

Catovirus(50.0%)

integrase,tRNA

attL 377756:377772|attR 389961:389977

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000425353.1\|376784_379415_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	3.7e-153	40.7
377756:377772	attL	NA	NA	NA	NA
WP_001108346.1\|379427_380699_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000261115.1\|380968_381676_+	prepilin peptidase	NA	NA	NA	NA
WP_000868132.1\|382345_383431_+\|integrase	tyrosine-type recombinase/integrase	A0A0A8WIF9	Clostridium_phage	4.5e-12	28.3
389961:389977	attR	NA	NA	NA	NA

DBSCAN-SWA_24

386762 : 387494

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001072201.1\|386762_387494_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A)	E4ZFQ0	Streptococcus_phage	1.9e-51	47.5

DBSCAN-SWA_25

396036 : 431648

uncultured_Mediterranean_phage(18.75%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001005768.1\|396036_397041_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
WP_001019178.1\|397042_398068_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001112045.1\|398090_399230_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001160682.1\|399248_399509_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_173896723.1\|399783_402063_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.1e-31	35.8
WP_000595011.1\|402265_404539_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000364542.1\|404560_405079_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_001058587.1\|405506_407696_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	6.9e-12	37.7
WP_000717800.1\|408155_409031_+	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	4.7e-12	33.7
WP_000590826.1\|409491_410754_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_000044799.1\|410769_412536_+\|tRNA	aspartate--tRNA ligase	A0A2K9L0E9	Tupanvirus	1.3e-16	27.3
WP_001790559.1\|412868_412997_+	hypothetical protein	NA	NA	NA	NA
WP_000682646.1\|412996_413770_+\|tRNA	tRNA threonylcarbamoyladenosine dehydratase	NA	NA	NA	NA
WP_000102726.1\|413930_415205_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	3.1e-105	50.5
WP_000704122.1\|415289_415712_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_000752909.1\|415811_415994_+	CsbD family protein	NA	NA	NA	NA
WP_000009238.1\|416033_416180_+	hypothetical protein	NA	NA	NA	NA
WP_000985878.1\|416416_417430_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_000409157.1\|417741_418884_+	cysteine desulfurase	A0A1X7QGF3	Faustovirus	5.4e-32	30.8
WP_000066097.1\|418884_420003_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000567017.1\|420697_421366_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_001283312.1\|421367_423845_+	ATP-dependent RecD-like DNA helicase	A0A0K2FLP8	Brevibacillus_phage	1.1e-66	29.0
WP_000734075.1\|424187_426818_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.2e-64	34.4
WP_000426912.1\|426880_427141_+	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_000939059.1\|427144_427573_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_000134779.1\|427587_427896_+	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_000342258.1\|428180_428819_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	3.2e-10	28.8
WP_000137774.1\|428821_429745_+	U32 family peptidase	NA	NA	NA	NA
WP_000848304.1\|429756_431025_+	U32 family peptidase	Q6DW11	Phage_TP	4.0e-36	31.7
WP_000648617.1\|431024_431648_+	uridine kinase	A0A1V0SAA3	Catovirus	2.8e-35	41.1

DBSCAN-SWA_26

448328 : 454492

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000439693.1\|448328_448790_+	ComE operon protein 2	A7KUY9	Bacillus_phage	3.6e-35	58.8
WP_001557362.1\|448794_450996_+	DNA internalization-related competence protein ComEC/Rec2	Q332C0	Clostridium_botulinum_C_phage	1.6e-32	32.2
WP_001282563.1\|451052_452027_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_001274017.1\|452071_452323_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_000368338.1\|452668_454492_+	elongation factor 4	A0A1S5SF82	Streptococcus_phage	6.1e-22	25.1

DBSCAN-SWA_27

457986 : 461094

Micromonas_pusilla_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000034716.1\|457986_459819_+	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	4.4e-137	46.5
WP_001119021.1\|459954_461094_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.2e-26	25.8

DBSCAN-SWA_28

467564 : 468512

Rhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001117767.1\|467564_468512_+	PhoH family protein	L7TP00	Rhizobium_phage	6.4e-47	46.8

DBSCAN-SWA_29

471565 : 485311

Klosneuvirus(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001030080.1\|471565_472957_-\|tRNA	glycine--tRNA ligase	A0A1V0SIF1	Klosneuvirus	4.7e-46	27.4
WP_001797828.1\|473291_473915_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000411298.1\|473925_474744_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_001217241.1\|474804_476622_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.4e-53	36.3
WP_001283055.1\|476845_477952_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_000624577.1\|478082_478760_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000683940.1\|478762_479863_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_001062177.1\|479976_481323_+	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000924220.1\|481332_482223_+	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001213908.1\|482348_483134_+	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000564315.1\|483175_484039_+	metal ABC transporter permease	NA	NA	NA	NA
WP_001095260.1\|484025_484436_+	transcriptional repressor	NA	NA	NA	NA
WP_000863556.1\|484711_485311_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	9.2e-60	54.7

DBSCAN-SWA_30

491484 : 492108

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001223008.1\|491484_492108_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.6e-30	37.1

DBSCAN-SWA_31

497652 : 500464

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000019691.1\|497652_498999_+	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	E3SN07	Prochlorococcus_phage	1.7e-61	39.2
WP_000202188.1\|498991_500464_+	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	E3SN07	Prochlorococcus_phage	2.8e-81	41.3

DBSCAN-SWA_32

507964 : 514535

Indivirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001286924.1\|507964_509302_+	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	1.6e-43	37.7
WP_000159865.1\|509294_509525_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_000183383.1\|509502_510384_+	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	2.0e-10	25.8
WP_001124985.1\|510815_511268_+	transcriptional regulator ArgR	NA	NA	NA	NA
WP_000942210.1\|511283_512963_+	DNA repair protein RecN	NA	NA	NA	NA
WP_001291533.1\|513113_514535_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	5.1e-40	26.3

DBSCAN-SWA_33

521364 : 522771

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000193707.1\|521364_522771_+	NADP-dependent phosphogluconate dehydrogenase	A0A222YX62	Synechococcus_phage	4.3e-31	31.1

DBSCAN-SWA_34

529197 : 530682

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000105070.1\|529197_530682_-	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	2.4e-80	37.8

DBSCAN-SWA_35

534209 : 628589

118

Staphylococcus_phage(76.47%)

tRNA,head,plate,protease,holin,tail,integrase,capsid,terminase,portal

attL 545615:545643|attR 591287:591315

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001171335.1\|534209_535118_-	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	4.4e-05	32.0
WP_000365240.1\|535199_535742_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000392691.1\|535846_536296_+	transcriptional repressor	NA	NA	NA	NA
WP_000447733.1\|536344_537232_+	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	5.6e-37	31.1
WP_001183429.1\|537309_537816_-	DUF309 domain-containing protein	NA	NA	NA	NA
WP_000273371.1\|537907_538639_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	7.9e-05	21.8
WP_000368656.1\|538631_539174_+	SMC-Scp complex subunit ScpB	NA	NA	NA	NA
WP_000159577.1\|539166_539904_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000064078.1\|540036_540762_+	two-component system response regulator SrrA	W8CYM9	Bacillus_phage	3.5e-45	43.0
WP_000987774.1\|540742_542494_+	two-component system sensor histidine kinase SrrB	A0A1V0SGX0	Hokovirus	2.2e-21	33.2
WP_001557355.1\|542737_543664_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001558502.1\|543656_545684_+	hypothetical protein	B5WZK7	Staphylococcus_phage	1.6e-116	100.0
545615:545643	attL	NA	NA	NA	NA
WP_000264751.1\|545726_546932_-\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_000191466.1\|547057_547672_+	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_001794606.1\|547668_547815_-	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	2.6e-16	97.9
WP_000705240.1\|547850_548033_-	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
WP_000511090.1\|548102_548834_-	helix-turn-helix transcriptional regulator	S4SVC5	Staphylococcus_phage	1.3e-132	99.2
WP_000213811.1\|548985_549198_+	helix-turn-helix transcriptional regulator	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
WP_000435357.1\|549245_549689_+	hypothetical protein	A7TWF2	Staphylococcus_phage	8.9e-76	100.0
WP_000771849.1\|549703_549853_+	hypothetical protein	D2JGJ0	Staphylococcus_phage	1.4e-20	100.0
WP_000362644.1\|549893_550106_-	hypothetical protein	D2JGJ1	Staphylococcus_phage	7.6e-33	100.0
WP_031898325.1\|550175_550373_+	hypothetical protein	A7TWF5	Staphylococcus_phage	5.9e-24	84.6
WP_000773059.1\|550359_550740_-	DUF2513 domain-containing protein	Q4ZCQ5	Staphylococcus_virus	5.8e-68	100.0
WP_001025401.1\|550806_551052_+	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_001128433.1\|551020_551386_-	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001097552.1\|551440_551656_+	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001124160.1\|551680_551944_+	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001285954.1\|551956_552118_+	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_000174998.1\|552196_552520_+	hypothetical protein	A0A2I6PE70	Staphylococcus_phage	6.5e-52	100.0
WP_000985971.1\|552534_552897_+	hypothetical protein	A0A2I6PEM7	Staphylococcus_phage	1.9e-55	99.2
WP_000762538.1\|552893_554060_+	DUF2800 domain-containing protein	R4WAL0	Staphylococcus_phage	1.5e-218	98.7
WP_000645045.1\|554085_554643_+	DUF2815 family protein	A0A2K9VBT2	Staphylococcus_phage	1.8e-97	100.0
WP_075339477.1\|554711_556664_+	DNA polymerase	A0A2K9VBT3	Staphylococcus_phage	0.0e+00	99.7
WP_001164629.1\|556676_556862_+	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_000022719.1\|557260_557515_+	DUF3310 domain-containing protein	A7TWG9	Staphylococcus_phage	2.2e-42	100.0
WP_060474161.1\|557514_557763_+	hypothetical protein	A0A2K9VBX5	Staphylococcus_phage	1.2e-40	100.0
WP_000693989.1\|557776_557983_+	hypothetical protein	A0A2K9VBT9	Staphylococcus_phage	3.0e-34	100.0
WP_000695753.1\|557985_558390_+	hypothetical protein	A0A0E3T8H9	Staphylococcus_phage	1.0e-70	98.5
WP_000979209.1\|558386_558734_+	hypothetical protein	D2JGL4	Staphylococcus_phage	5.9e-59	100.0
WP_000144698.1\|558730_559039_+	hypothetical protein	Q4ZBK6	Staphylococcus_phage	3.1e-51	99.0
WP_001065104.1\|559031_559286_+	DUF1024 family protein	A7TWH5	Staphylococcus_phage	6.1e-37	92.9
WP_000714407.1\|559272_559443_+	hypothetical protein	A0A1W6JQ22	Staphylococcus_phage	5.7e-23	100.0
WP_001066454.1\|559435_559972_+	dUTP diphosphatase	A0A1W6JPM9	Staphylococcus_phage	4.6e-95	99.4
WP_000195832.1\|560008_560215_+	DUF1381 domain-containing protein	A7TWH8	Staphylococcus_phage	4.9e-29	97.1
WP_000141259.1\|560211_560415_+	hypothetical protein	A7TWH9	Staphylococcus_phage	8.8e-31	100.0
WP_000608283.1\|560407_560644_+	hypothetical protein	A7TWI0	Staphylococcus_phage	3.6e-36	100.0
WP_001596346.1\|560633_561023_+	hypothetical protein	A7TWI1	Staphylococcus_phage	3.6e-65	100.0
WP_000595269.1\|561019_561172_+	transcriptional activator RinB	A7TWI2	Staphylococcus_phage	1.3e-18	98.0
WP_000265258.1\|561239_561440_+	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000884860.1\|561492_563940_+	virulence-associated E family protein	M1RZC5	Staphylococcus_phage	0.0e+00	99.5
WP_015978074.1\|564042_564147_-	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	2.7e-12	100.0
WP_000665205.1\|564280_564571_+	VRR-NUC domain-containing protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
WP_001795330.1\|564551_565919_+	DEAD/DEAH box helicase	Q4ZCF6	Staphylococcus_virus	4.6e-264	100.0
WP_000513702.1\|565931_566369_+	transcriptional regulator	B7T0I6	Staphylococcus_virus	6.1e-77	100.0
WP_000166884.1\|566525_566846_+	HNH endonuclease	A0A2K9VBV6	Staphylococcus_phage	1.1e-56	99.1
WP_000778935.1\|566970_567276_+\|terminase	P27 family phage terminase small subunit	U5U414	Staphylococcus_phage	2.9e-49	100.0
WP_000152858.1\|567265_568957_+\|terminase	terminase large subunit	A0A2K9VBQ1	Staphylococcus_phage	0.0e+00	100.0
WP_001100660.1\|568961_570200_+\|portal	phage portal protein	A0A2K9VBP0	Staphylococcus_phage	2.0e-234	99.5
WP_000061872.1\|570183_570957_+\|protease	Clp protease ClpP	M1TAZ4	Staphylococcus_phage	9.2e-137	100.0
WP_001142739.1\|570968_572132_+\|capsid	phage major capsid protein	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
WP_000050973.1\|572200_572479_+\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_000395495.1\|572490_572823_+	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	8.2e-58	99.1
WP_000110020.1\|572819_573221_+	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
WP_001023802.1\|573221_573617_+	DUF3168 domain-containing protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
WP_000807536.1\|573651_574293_+\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_000169128.1\|574384_574840_+	Ig domain-containing protein	A0A2I6PF45	Staphylococcus_phage	1.3e-77	100.0
WP_000589165.1\|574897_575248_+	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	1.1e-55	100.0
WP_000438833.1\|575289_575448_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_001003456.1\|575461_581662_+\|tail	phage tail tape measure protein	A0A2I6PE73	Staphylococcus_phage	0.0e+00	99.3
WP_001190533.1\|581661_582486_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_000384474.1\|582494_584078_+\|tail	phage tail protein	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_000179858.1\|584077_584368_+	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000429558.1\|584383_586294_+	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_173896725.1\|586293_587760_+\|plate	phage baseplate upper protein	A0A2I6PES7	Staphylococcus_phage	2.2e-272	99.6
WP_001166599.1\|587759_588149_+	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_000916020.1\|588141_588306_+	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_000466784.1\|588351_588651_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000339146.1\|588786_589089_+\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
WP_000909213.1\|589099_590554_+	N-acetylmuramoyl-L-alanine amidase	U5U7D2	Staphylococcus_phage	2.6e-289	100.0
WP_000126130.1\|591275_591491_+	hypothetical protein	A0ZS61	Staphylococcus_virus	2.0e-25	100.0
591287:591315	attR	NA	NA	NA	NA
WP_000476865.1\|591580_592486_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476354.1\|592543_593440_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001557351.1\|593515_593770_+	hypothetical protein	NA	NA	NA	NA
WP_000913227.1\|593910_594867_+	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_001186912.1\|595268_595814_+	ECF transporter S component	NA	NA	NA	NA
WP_001151997.1\|595919_596168_-	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001163801.1\|596275_597229_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000902099.1\|597218_598598_+	ATP-dependent DNA helicase RecQ	A0A2P1EM61	Moumouvirus	1.4e-55	33.6
WP_000069291.1\|598750_600211_+	elastin-binding protein EbpS	NA	NA	NA	NA
WP_001792205.1\|600335_600452_+	hypothetical protein	NA	NA	NA	NA
WP_001174258.1\|600612_601599_+	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_000681757.1\|601713_602682_-	asparaginase	NA	NA	NA	NA
WP_000644391.1\|602758_603418_+	(d)CMP kinase	NA	NA	NA	NA
WP_001795818.1\|603448_603601_+	hypothetical protein	NA	NA	NA	NA
WP_001792202.1\|603681_603873_+	hypothetical protein	NA	NA	NA	NA
WP_000133961.1\|604129_605305_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_153174329.1\|605526_606837_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000161745.1\|606853_607852_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_001043863.1\|608022_608295_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000450555.1\|608709_609282_+	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_000774684.1\|609284_610010_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_001096471.1\|610011_610971_+	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000442480.1\|611062_611512_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_000789522.1\|611720_611921_+	hypothetical protein	NA	NA	NA	NA
WP_001269921.1\|612306_613473_+	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	31.8
WP_000776312.1\|613498_614563_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_000253232.1\|614572_615871_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000389524.1\|615877_617122_+	hypothetical protein	NA	NA	NA	NA
WP_000005212.1\|617135_617711_+	YpiB family protein	G3MAV7	Bacillus_virus	2.1e-08	27.2
WP_000154683.1\|617700_618288_+	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_001827022.1\|618359_619040_+	zinc metallopeptidase	NA	NA	NA	NA
WP_000839926.1\|619375_619693_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_000690025.1\|619936_621079_+	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000361540.1\|621083_622286_+\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	4.2e-35	43.3
WP_000049921.1\|622272_623244_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000525078.1\|623267_625961_+	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000858779.1\|626282_627575_+\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	8.7e-55	31.3
WP_000362218.1\|627902_628589_+	DnaD domain-containing protein	Q938N2	Temperate_phage	1.2e-07	32.6

DBSCAN-SWA_36

632329 : 633007

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001795446.1\|632329_633007_-	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	1.9e-24	35.5

DBSCAN-SWA_37

642281 : 643160

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001133021.1\|642281_643160_+	5'-3' exonuclease	S5M4P0	Bacillus_phage	1.4e-19	29.5

DBSCAN-SWA_38

682119 : 691509

Staphylococcus_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000282171.1\|682119_682824_-	queuosine precursor transporter	A0A2H4J2N7	uncultured_Caudovirales_phage	8.4e-12	23.8
WP_001795441.1\|683068_683263_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_000691942.1\|683274_683526_+	NifU N-terminal domain-containing protein	NA	NA	NA	NA
WP_000404645.1\|683563_684688_+	virulence factor C	NA	NA	NA	NA
WP_000995287.1\|684703_685141_+	BrxA/BrxB family bacilliredoxin	NA	NA	NA	NA
WP_000934894.1\|685564_686521_+	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	1.6e-167	85.2
WP_000175746.1\|686720_687200_+	dihydrofolate reductase	A0A0N9S8H6	Staphylococcus_phage	2.0e-73	79.9
WP_000166059.1\|687214_688054_+	fatty acid kinase FakB2	A0A0N9SI50	Staphylococcus_phage	2.3e-48	77.3
WP_000159900.1\|688139_688673_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_000913317.1\|688665_689094_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_000473653.1\|689105_689606_+	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_000801007.1\|689605_689827_+	hypothetical protein	NA	NA	NA	NA
WP_000342132.1\|690018_691509_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	2.9e-22	30.5

DBSCAN-SWA_39

694918 : 696930

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000192137.1\|694918_695578_+	response regulator transcription factor ArlR	W8CYM9	Bacillus_phage	1.1e-34	33.8
WP_000166801.1\|695574_696930_+	sensor histidine kinase ArlS	A0A1V0SGX0	Hokovirus	3.5e-14	27.8

DBSCAN-SWA_40

703095 : 703887

Halovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001185421.1\|703095_703887_+	MoxR family ATPase	R4TG24	Halovirus	3.3e-12	34.2

DBSCAN-SWA_41

707427 : 712458

Lactobacillus_phage(33.33%)

lysis

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000138413.1\|707427_708564_-	toxic anion resistance protein	A0A291I9K4	Lactobacillus_phage	7.4e-34	28.3
WP_001788788.1\|708595_709225_-\|lysis	5-bromo-4-chloroindolyl phosphate hydrolysis family protein	NA	NA	NA	NA
WP_001215907.1\|709243_709513_-	acylphosphatase	NA	NA	NA	NA
WP_000269923.1\|709675_709984_+	DUF1033 family protein	NA	NA	NA	NA
WP_000809131.1\|710154_710355_+	cold-shock protein	Q9AZD3	Lactococcus_phage	8.4e-18	66.2
WP_000876201.1\|710551_710953_+	sarA expression modulator protein Msa	NA	NA	NA	NA
WP_000216946.1\|711192_712458_-	diaminopimelate decarboxylase	A0A0P0YM38	Yellowstone_lake_phycodnavirus	6.2e-13	23.2

DBSCAN-SWA_42

720505 : 722107

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000942303.1\|720505_722107_-	ATP-binding cassette domain-containing protein	A0A1V0SKJ1	Klosneuvirus	5.5e-51	25.7

DBSCAN-SWA_43

727196 : 730650

Indivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000079447.1\|727196_728048_+	phosphate ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	8.9e-16	29.7
WP_000974847.1\|728054_728696_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_000077555.1\|728835_730650_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	1.4e-154	47.3

DBSCAN-SWA_44

734064 : 734766

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571259.1\|734064_734766_+	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	2.0e-13	30.3

DBSCAN-SWA_45

742864 : 745219

Acinetobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047211978.1\|742864_743647_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.5e-27	35.9
WP_000173833.1\|743648_744647_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	8.5e-34	34.9
WP_000604816.1\|744652_745219_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.3e-23	32.1

DBSCAN-SWA_46

749537 : 750800

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000283016.1\|749537_750800_-	Y-family DNA polymerase	O64031	Bacillus_phage	2.6e-96	44.3

DBSCAN-SWA_47

760459 : 764853

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001289590.1\|760459_762862_-	DNA topoisomerase IV subunit A	A0A172JHV7	Bacillus_phage	1.1e-92	32.2
WP_001557340.1\|762861_764853_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.0e-115	40.5

DBSCAN-SWA_48

770844 : 772491

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001088978.1\|770844_772491_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	2.5e-22	24.4

DBSCAN-SWA_49

776160 : 777282

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000691301.1\|776160_777282_-	exonuclease SbcCD subunit D	A0A1X9I9U0	Staphylococcus_phage	4.3e-10	22.7

DBSCAN-SWA_50

781432 : 787088

Phage_Wrath(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001208755.1\|781432_782056_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	5.9e-17	63.8
WP_001797872.1\|782435_783452_-	CAP domain-containing protein	U5Q0C0	Bacillus_phage	1.1e-15	41.5
WP_000688122.1\|783473_784451_-	GMP reductase	Q4ZCY7	Staphylococcus_virus	8.0e-186	99.7
WP_001085655.1\|784607_784877_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_001265708.1\|785330_785480_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_000082539.1\|785570_787088_-	catalase	A0A2K9L0T1	Tupanvirus	2.3e-91	43.2

DBSCAN-SWA_51

797226 : 801502

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000841351.1\|797226_797760_-	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	3.4e-21	43.5
WP_001027143.1\|797898_798087_+	hypothetical protein	NA	NA	NA	NA
WP_000202390.1\|798199_798802_-	response regulator transcription factor	NA	NA	NA	NA
WP_000670307.1\|798798_799890_-	sensor histidine kinase	NA	NA	NA	NA
WP_000603970.1\|799893_800625_-	ABC transporter permease	NA	NA	NA	NA
WP_000593436.1\|800593_801502_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.1e-22	25.9

DBSCAN-SWA_52

807161 : 810189

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000006110.1\|807161_807347_-	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
WP_001788716.1\|807770_807881_-	hypothetical protein	NA	NA	NA	NA
WP_001002340.1\|808580_808787_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.3e-13	59.7
WP_001071314.1\|809080_809293_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	4.8e-19	72.5
WP_001791958.1\|809991_810189_-	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.1e-09	48.4

DBSCAN-SWA_53

815258 : 815735

Fowlpox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448078.1\|815258_815735_+	glutathione peroxidase	Q70H87	Fowlpox_virus	1.2e-22	38.0

DBSCAN-SWA_54

821677 : 828159

Acanthocystis_turfacea_Chlorella_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001103743.1\|821677_822496_-	aquaporin family protein	M1H4F4	Acanthocystis_turfacea_Chlorella_virus	2.4e-26	35.1
WP_001077635.1\|822970_823513_-	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_000516269.1\|823518_825528_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	4.8e-60	30.0
WP_000073352.1\|825540_828159_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	8.5e-41	23.7

DBSCAN-SWA_55

837573 : 838617

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000368166.1\|837573_838617_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	9.3e-124	69.2

DBSCAN-SWA_56

842815 : 848482

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000664775.1\|842815_844102_-	insulinase family protein	G3MBJ8	Bacillus_virus	7.9e-16	28.4
WP_000089941.1\|844101_845367_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.2e-40	26.8
WP_001293306.1\|845397_846111_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000035746.1\|846115_848482_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	7.3e-84	47.7

DBSCAN-SWA_57

853497 : 865310

Klosneuvirus(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864190.1\|853497_854469_-	riboflavin biosynthesis protein RibF	A0A1V0SJE1	Klosneuvirus	1.7e-07	32.1
WP_000282298.1\|854483_855401_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000097322.1\|855569_855920_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000043635.1\|856305_858423_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	2.4e-25	25.1
WP_000020853.1\|858427_858745_-	YlxQ family RNA-binding protein	NA	NA	NA	NA
WP_000727423.1\|858741_859026_-	YlxR family protein	NA	NA	NA	NA
WP_000097460.1\|859046_860222_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000036633.1\|860242_860710_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_001801936.1\|860999_865310_-	DNA polymerase III subunit alpha	A0A0A8WJ41	Clostridium_phage	3.5e-23	41.2

DBSCAN-SWA_58

869583 : 870354

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000473699.1\|869583_870354_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	7.3e-25	41.5

DBSCAN-SWA_59

875133 : 888807

Erwinia_phage(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000379054.1\|875133_876537_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IDZ7	Erwinia_phage	4.9e-27	25.6
WP_000072681.1\|876602_877148_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_001015601.1\|877144_878041_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.6e-31	31.9
WP_000195254.1\|878458_879766_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_001557331.1\|879921_881997_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	1.7e-105	39.2
WP_000672869.1\|883217_884462_-	FemA/FemB family glycyltransferase FmhC	NA	NA	NA	NA
WP_001041666.1\|884489_885608_-	LysM peptidoglycan-binding domain-containing protein	A0A1W6JQB6	Staphylococcus_phage	9.5e-50	61.1
WP_000110253.1\|885834_886743_-	succinate--CoA ligase subunit alpha	A0A2K9L1S3	Tupanvirus	3.0e-17	33.2
WP_001020801.1\|886764_887931_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_000176393.1\|888039_888807_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	2.5e-25	44.1

DBSCAN-SWA_60

902191 : 904441

Acanthamoeba_polyphaga_mimivirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000043237.1\|902191_902923_-	ribonuclease III	A0A0G2Y7P9	Acanthamoeba_polyphaga_mimivirus	5.9e-24	28.8
WP_000426914.1\|903038_903272_-	acyl carrier protein	E3SSM9	Prochlorococcus_phage	1.6e-07	63.3
WP_000167269.1\|903706_904441_-	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	3.1e-17	30.3

DBSCAN-SWA_61

914811 : 916806

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000579563.1\|914811_916806_-	serine/threonine protein kinase Stk1	M1PCM5	Moumouvirus	5.5e-24	34.8

DBSCAN-SWA_62

919953 : 920889

Prochlorococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161291.1\|919953_920889_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	4.7e-10	28.0

DBSCAN-SWA_63

925901 : 928158

Methanothermobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000722165.1\|925901_927101_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.2e-42	32.9
WP_000933956.1\|927316_927535_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_000368226.1\|927534_928158_-	guanylate kinase	A0A143DIC6	Abalone_herpesvirus	1.0e-21	34.1

DBSCAN-SWA_64

931472 : 932084

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001040248.1\|931472_932084_-	orotate phosphoribosyltransferase	S4VS55	Pandoravirus	1.6e-27	33.8

DBSCAN-SWA_65

936051 : 940662

Halovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001190913.1\|936051_937152_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	5.6e-63	36.7
WP_000767028.1\|937153_938428_-	dihydroorotase	NA	NA	NA	NA
WP_001016166.1\|938445_939327_-	aspartate carbamoyltransferase catalytic subunit	A0A1J0F9B8	Only_Syngen_Nebraska_virus	4.6e-31	33.9
WP_001178619.1\|939354_940662_-	uracil permease	Q9KX94	Enterobacteria_phage	3.3e-54	34.0

DBSCAN-SWA_66

945126 : 947880

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000384691.1\|945126_947880_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	3.6e-90	28.0

DBSCAN-SWA_67

967463 : 967652

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001245796.1\|967463_967652_-	hypothetical protein	A0A0K1LL29	Staphylococcus_phage	2.5e-19	85.2

DBSCAN-SWA_68

976668 : 978628

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001802045.1\|976668_976893_-	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	5.6e-18	71.4
WP_000765708.1\|976849_976996_-	hypothetical protein	NA	NA	NA	NA
WP_000857488.1\|977668_978628_+	alpha-hemolysin	A0A2H4PQH7	Staphylococcus_phage	7.4e-35	30.3

DBSCAN-SWA_69

994265 : 998823

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001018928.1\|994265_994580_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	46.6
WP_001249272.1\|994752_997101_-	endonuclease MutS2	F2QAF8	Phaeocystis_pouchetii_virus	3.2e-15	25.1
WP_000161938.1\|997110_998823_-	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	6.8e-15	24.0

DBSCAN-SWA_70

1003825 : 1004884

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000003566.1\|1003825_1004884_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5

DBSCAN-SWA_71

1016830 : 1019738

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000401377.1\|1016830_1017313_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.6e-28	46.2
WP_173896735.1\|1017314_1017857_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_000814565.1\|1017926_1018316_+	hypothetical protein	NA	NA	NA	NA
WP_001049150.1\|1018318_1018573_-	YlbG family protein	NA	NA	NA	NA
WP_000757575.1\|1018811_1019738_+	glycerophosphodiester phosphodiesterase	M1I1K8	Paramecium_bursaria_Chlorella_virus	2.2e-12	26.2

DBSCAN-SWA_72

1031255 : 1033103

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000182653.1\|1031255_1033103_-	translational GTPase TypA	A0A2K5B2A5	Erysipelothrix_phage	1.8e-21	26.2

DBSCAN-SWA_73

1041231 : 1050064

Mycoplasma_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000433551.1\|1041231_1042326_-	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	1.4e-37	44.3
WP_001020621.1\|1042338_1042878_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000455597.1\|1043021_1043297_-	UPF0223 family protein	NA	NA	NA	NA
WP_000260117.1\|1043464_1044871_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.2e-46	29.1
WP_000863439.1\|1044874_1046167_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_000068176.1\|1046257_1047235_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_000035320.1\|1047238_1048351_-	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	A0A0K0KW14	Prochlorococcus_phage	1.4e-05	27.8
WP_000668336.1\|1048521_1049148_-	YkyA family protein	NA	NA	NA	NA
WP_000957037.1\|1049512_1050064_+	peptide deformylase	E3SLL2	Synechococcus_phage	1.6e-13	42.0

DBSCAN-SWA_74

1056076 : 1126434

Bacillus_virus(11.11%)

protease,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001289618.1\|1056076_1056310_+	glutaredoxin-like protein NrdH	G3MBF0	Bacillus_virus	8.4e-09	38.7
WP_000040051.1\|1056546_1058265_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_000437472.1\|1058267_1058534_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_000505966.1\|1058687_1059230_-	hypothetical protein	NA	NA	NA	NA
WP_000685067.1\|1059283_1060456_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	4.0e-75	42.8
WP_001557163.1\|1060844_1062164_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000009069.1\|1062400_1063696_-	hypothetical protein	NA	NA	NA	NA
WP_000064214.1\|1063847_1063982_+	hypothetical protein	NA	NA	NA	NA
WP_000033477.1\|1064754_1065330_+	ECF transporter S component	NA	NA	NA	NA
WP_000921965.1\|1065344_1066745_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-10	26.3
WP_000273253.1\|1066737_1067544_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_001101899.1\|1067810_1069058_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_000709277.1\|1069079_1070558_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.2e-77	51.8
WP_000238669.1\|1070572_1071139_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	6.1e-29	40.1
WP_000030811.1\|1071141_1072170_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000483720.1\|1072162_1073647_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000032740.1\|1073625_1075815_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000666806.1\|1075807_1076479_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_150344384.1\|1076480_1076744_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000174053.1\|1076743_1077448_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_001010413.1\|1077451_1078576_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000861573.1\|1078562_1079045_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	44.7
WP_000225836.1\|1079245_1080106_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	4.4e-39	38.8
WP_001037831.1\|1080969_1081287_+	DUF5011 domain-containing protein	NA	NA	NA	NA
WP_031761471.1\|1081427_1081553_-	hypothetical protein	NA	NA	NA	NA
WP_000032836.1\|1081857_1082958_+	cytochrome aa3 quinol oxidase subunit II	NA	NA	NA	NA
WP_001010762.1\|1082957_1084946_+	cytochrome aa3 quinol oxidase subunit I	NA	NA	NA	NA
WP_000017736.1\|1084935_1085541_+	cytochrome aa3 quinol oxidase subunit III	NA	NA	NA	NA
WP_001797236.1\|1085549_1085828_+	cytochrome aa3 quinol oxidase subunit IV	NA	NA	NA	NA
WP_000671245.1\|1086364_1087558_-	teichoic acid D-Ala esterase FmtA	NA	NA	NA	NA
WP_001031978.1\|1088008_1089226_+	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase	NA	NA	NA	NA
WP_000088431.1\|1089273_1089744_+	DUF2538 family protein	NA	NA	NA	NA
WP_000491986.1\|1089898_1090333_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001074534.1\|1090560_1094307_+	bifunctional autolysin	A0A1J0MFB0	Staphylococcus_phage	1.1e-54	37.6
WP_001788579.1\|1094376_1094487_-	hypothetical protein	NA	NA	NA	NA
WP_000278015.1\|1094513_1094933_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000202433.1\|1095085_1096096_+	acyltransferase family protein	NA	NA	NA	NA
WP_000777577.1\|1096291_1097446_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000676539.1\|1097973_1099002_+	Glu-specific serine endopeptidase SspA	A0A2H4PQP7	Staphylococcus_phage	6.3e-16	32.3
WP_001089094.1\|1099083_1100265_+\|protease	cysteine protease staphopain B	NA	NA	NA	NA
WP_000284458.1\|1100302_1100632_+	staphostatin B	NA	NA	NA	NA
WP_000184945.1\|1100869_1101691_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000150197.1\|1101683_1102487_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000526694.1\|1102473_1104147_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_000190622.1\|1104133_1105495_-	isochorismate synthase MenF	NA	NA	NA	NA
WP_000070966.1\|1105676_1106615_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000620949.1\|1106666_1107218_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000867357.1\|1107382_1107598_+	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	1.5e-07	49.1
WP_001790177.1\|1107661_1107793_+	hypothetical protein	NA	NA	NA	NA
WP_001081351.1\|1107838_1108798_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001792054.1\|1109731_1109869_-	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_001795266.1\|1110009_1110300_+	hypothetical protein	NA	NA	NA	NA
WP_000571167.1\|1110387_1111029_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
WP_000668627.1\|1111025_1111346_-	YxeA family protein	NA	NA	NA	NA
WP_000870829.1\|1111348_1113313_-\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_001797239.1\|1113356_1113629_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_001792055.1\|1113638_1113740_-	hypothetical protein	NA	NA	NA	NA
WP_001033865.1\|1114655_1115258_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000214898.1\|1115272_1115449_-	YkvS family protein	NA	NA	NA	NA
WP_000668818.1\|1115647_1116634_+	lipoate--protein ligase	NA	NA	NA	NA
WP_000876826.1\|1116714_1116933_-	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000287265.1\|1117142_1117712_+	competence protein ComK	NA	NA	NA	NA
WP_000414165.1\|1118198_1119710_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000021865.1\|1119848_1121207_-	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_001795272.1\|1121223_1123548_-\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000928413.1\|1123766_1124570_-	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001049950.1\|1124871_1126434_-	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2

DBSCAN-SWA_75

1145366 : 1147175

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000082725.1\|1145366_1147175_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5

DBSCAN-SWA_76

1152987 : 1154957

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000427767.1\|1152987_1153968_-	dipeptide ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-15	33.5
WP_001067052.1\|1153970_1154957_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.4e-15	29.6

DBSCAN-SWA_77

1158608 : 1160622

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000786734.1\|1158608_1159550_-	ATP-binding cassette domain-containing protein	F2Y1V6	Organic_Lake_phycodnavirus	1.6e-05	26.9
WP_000140050.1\|1159539_1160622_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.4e-19	28.8

DBSCAN-SWA_78

1169213 : 1176023

Micromonas_sp._RCC1109_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000619360.1\|1169213_1170359_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	1.5e-05	26.0
WP_001047069.1\|1170468_1171338_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_000353951.1\|1171396_1174006_-	ATP-dependent chaperone ClpB	A0A223W0B1	Agrobacterium_phage	8.0e-116	34.2
WP_001044230.1\|1174208_1176023_-	acetyltransferase	B5WZU0	Pseudomonas_phage	6.7e-37	33.9

DBSCAN-SWA_79

1181142 : 1184796

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000154921.1\|1181142_1184796_-	helicase-exonuclease AddAB subunit AddA	A7KV33	Bacillus_phage	2.0e-24	24.5

DBSCAN-SWA_80

1194950 : 1202132

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000185319.1\|1194950_1195880_+	glycerophosphodiester phosphodiesterase	A0A220BYK6	Staphylococcus_phage	3.7e-39	37.9
WP_000138487.1\|1196406_1197651_-	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_000167309.1\|1197759_1198950_-	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	1.0e-33	29.7
WP_000838029.1\|1199257_1200385_-	NADH-dependent flavin oxidoreductase	NA	NA	NA	NA
WP_001067294.1\|1200746_1201124_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_000035058.1\|1201538_1202132_-	peptidylprolyl isomerase	A0A076FI46	Aureococcus_anophage	1.1e-25	41.3

DBSCAN-SWA_81

1212052 : 1215680

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001009692.1\|1212052_1213528_-	cytosol aminopeptidase	Q6GYZ8	Mycoplasma_phage	4.5e-47	34.9
WP_000046076.1\|1213658_1214867_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_001143495.1\|1215320_1215680_-	iron-sulfur cluster assembly accessory protein	A0A2H4N7M3	Lake_Baikal_phage	2.7e-14	38.6

DBSCAN-SWA_82

1219723 : 1222392

Pseudomonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000613541.1\|1219723_1220938_-	PG:teichoic acid D-alanyltransferase DltB	A0A125RNP0	Pseudomonas_phage	8.5e-20	26.1
WP_000129659.1\|1220934_1222392_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9L3I8	Tupanvirus	2.6e-39	28.5

DBSCAN-SWA_83

1237206 : 1240729

environmental_halophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001006450.1\|1237206_1238457_-	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.8
WP_000205567.1\|1238562_1239870_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000168845.1\|1239967_1240729_-	Fe-S cluster assembly ATPase SufC	A0A1V0SE00	Indivirus	4.4e-06	23.3

DBSCAN-SWA_84

1244216 : 1245242

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571213.1\|1244216_1245242_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.4e-28	36.8

DBSCAN-SWA_85

1248562 : 1253761

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000589549.1\|1248562_1248919_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.7e-19	46.6
WP_001147952.1\|1249062_1249383_+	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	3.1e-06	36.4
WP_000422908.1\|1249533_1250073_-	nitroreductase	NA	NA	NA	NA
WP_000150011.1\|1250155_1250872_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.5e-16	30.1
WP_000974460.1\|1251019_1251442_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000569883.1\|1251840_1252335_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000255551.1\|1252489_1253107_+	amino acid transporter	NA	NA	NA	NA
WP_001140693.1\|1253179_1253761_-	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	5.5e-33	40.9

DBSCAN-SWA_86

1257140 : 1258384

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001059082.1\|1257140_1257341_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.4e-20	70.8
WP_000141557.1\|1257697_1258384_-	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	1.7e-33	54.2

DBSCAN-SWA_87

1267445 : 1276322

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000757397.1\|1267445_1268174_+	DUF5067 domain-containing protein	H9A0X8	Staphylococcus_phage	1.3e-18	37.5
WP_001058299.1\|1268527_1268851_+	hypothetical protein	NA	NA	NA	NA
WP_001085183.1\|1270172_1270637_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.6e-80	98.7
WP_001050048.1\|1270658_1273031_-	ribonuclease R	Q0GXV6	Lactococcus_phage	4.3e-92	38.8
WP_001165959.1\|1273064_1273805_-	carboxylesterase	NA	NA	NA	NA
WP_000556760.1\|1273920_1274154_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000785252.1\|1274220_1274679_-	hypothetical protein	NA	NA	NA	NA
WP_001121760.1\|1275017_1276322_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.7e-196	80.7

DBSCAN-SWA_88

1285549 : 1291480

Streptococcus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001049165.1\|1285549_1286137_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.2e-53	55.3
WP_000006551.1\|1286700_1287645_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	3.1e-54	40.6
WP_001248939.1\|1287755_1288751_-	YvcK family protein	A1IMD5	Streptococcus_phage	4.8e-53	41.9
WP_000369722.1\|1288747_1289659_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.1e-08	36.1
WP_000134963.1\|1290544_1291480_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.9e-84	49.2

DBSCAN-SWA_89

1295927 : 1298774

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000662677.1\|1295927_1298774_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.2

DBSCAN-SWA_90

1302092 : 1302932

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000753319.1\|1302092_1302932_-	CHAP domain-containing protein	A0A2H4J675	uncultured_Caudovirales_phage	3.5e-12	42.2

DBSCAN-SWA_91

1309010 : 1314716

Streptococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001557172.1\|1309010_1310093_-	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	9.9e-44	35.2
WP_000686344.1\|1310456_1311323_-	DegV family protein	NA	NA	NA	NA
WP_000192949.1\|1311466_1312108_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.3e-37	47.7
WP_000258150.1\|1312272_1313328_-	undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase	NA	NA	NA	NA
WP_000460983.1\|1313645_1314716_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.3e-16	33.5

DBSCAN-SWA_92

1323995 : 1347468

uncultured_Caudovirales_phage(35.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000616840.1\|1323995_1324757_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6
WP_001245577.1\|1324753_1325710_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000876318.1\|1325696_1326668_-	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_000499195.1\|1326706_1326862_-	hypothetical protein	NA	NA	NA	NA
WP_000562498.1\|1327042_1328014_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000855514.1\|1328131_1330237_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000692521.1\|1330199_1330598_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_001068501.1\|1331398_1332265_+	DMT family transporter	NA	NA	NA	NA
WP_000930014.1\|1332284_1332785_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_000193751.1\|1333125_1334631_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_031760357.1\|1334708_1334810_-	hypothetical protein	NA	NA	NA	NA
WP_000429006.1\|1334900_1335818_+	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_000197262.1\|1336696_1337239_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000663030.1\|1337577_1338636_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000180991.1\|1338875_1340390_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_000589247.1\|1340382_1341360_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.4e-25	33.3
WP_000983677.1\|1341581_1343363_-	DNA helicase RecQ	A0A2P1EM61	Moumouvirus	6.5e-77	37.0
WP_000525106.1\|1343374_1345258_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.0e-55	30.6
WP_000098285.1\|1345527_1347468_-	polyglycerol-phosphate lipoteichoic acid synthase LtaS	W6LM83	Streptococcus_phage	1.3e-110	39.5

DBSCAN-SWA_93

1350607 : 1360454

Pandoravirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001217796.1\|1350607_1351759_-	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	6.0e-23	35.7
WP_000604514.1\|1351742_1352336_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_000446724.1\|1352686_1353355_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000941336.1\|1353356_1353776_+	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_001062972.1\|1353779_1354493_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000604990.1\|1354591_1355176_+	hypothetical protein	NA	NA	NA	NA
WP_001093562.1\|1355455_1355896_+	DM13 domain-containing protein	NA	NA	NA	NA
WP_001037807.1\|1356238_1356712_+	DoxX family protein	NA	NA	NA	NA
WP_000149344.1\|1356686_1357373_+	response regulator transcription factor	NA	NA	NA	NA
WP_000244415.1\|1357372_1358428_+	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000702781.1\|1358499_1359483_-	lipoteichoic acid-specific glycosylation protein CsbB	A0A192Y8W7	Salmonella_phage	1.5e-62	43.3
WP_000931238.1\|1359614_1360454_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.6e-55	41.5

DBSCAN-SWA_94

1372070 : 1373444

Powai_lake_megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000952038.1\|1372070_1373444_-	deoxyribodipyrimidine photo-lyase	A0A167RC11	Powai_lake_megavirus	2.3e-45	33.6

DBSCAN-SWA_95

1378421 : 1384701

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000857598.1\|1378421_1380095_-	amino acid ABC transporter ATP-binding/permease protein	W8CYL7	Bacillus_phage	3.4e-11	23.2
WP_000737160.1\|1380091_1381723_-	ABC transporter ATP-binding protein/permease	W5SAS9	Pithovirus	6.7e-12	27.8
WP_000469894.1\|1381941_1382817_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_000358498.1\|1382988_1383672_+	hypothetical protein	NA	NA	NA	NA
WP_000148826.1\|1383674_1384133_+	YaiI/YqxD family protein	NA	NA	NA	NA
WP_000820897.1\|1384134_1384701_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	4.7e-21	36.9

DBSCAN-SWA_96

1391491 : 1391965

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000833486.1\|1391491_1391965_-	cupin domain-containing protein	A0A291AU44	Pandoravirus	1.6e-14	39.4

DBSCAN-SWA_97

1397227 : 1398025

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000731644.1\|1397227_1398025_+	LysM peptidoglycan-binding domain-containing protein	A0A223LD43	Bacillus_phage	1.2e-06	30.2

DBSCAN-SWA_98

1404376 : 1405138

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000985996.1\|1404376_1405138_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-33	34.8

DBSCAN-SWA_99

1409512 : 1410556

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001030772.1\|1409512_1410556_-	alpha/beta hydrolase	A0A0G2YDK2	Acanthamoeba_polyphaga_mimivirus	2.0e-17	26.6

DBSCAN-SWA_100

1417079 : 1417877

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001080809.1\|1417079_1417877_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-18	30.7

DBSCAN-SWA_101

1421102 : 1425061

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000817954.1\|1421102_1422830_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.7e-110	43.3
WP_000793067.1\|1423250_1424546_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	2.0e-14	26.9
WP_000832260.1\|1424662_1425061_-	glycerol-3-phosphate cytidylyltransferase	A0A222YWT0	Streptomyces_phage	3.2e-16	39.9

DBSCAN-SWA_102

1431995 : 1432739

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000894464.1\|1431995_1432739_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.2e-11	29.7

DBSCAN-SWA_103

1445277 : 1445838

Streptococcus_phage(100.0%)

integrase

attL 1439431:1439445|attR 1449428:1449442

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1439431:1439445	attL	NA	NA	NA	NA
WP_001044915.1\|1445277_1445838_-\|integrase	tyrosine-type recombinase/integrase	A0A141E172	Streptococcus_phage	5.7e-19	35.1
WP_001044915.1\|1445277_1445838_-\|integrase	tyrosine-type recombinase/integrase	A0A141E172	Streptococcus_phage	5.7e-19	35.1
1449428:1449442	attR	NA	NA	NA	NA

DBSCAN-SWA_104

1458666 : 1462020

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001200748.1\|1458666_1459677_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	5.6e-33	27.3
WP_001792725.1\|1460175_1460697_-	YwhD family protein	NA	NA	NA	NA
WP_000180234.1\|1460724_1462020_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	1.2e-24	27.9

DBSCAN-SWA_105

1469592 : 1470915

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000860592.1\|1469592_1470915_+	FAD-containing oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	2.6e-107	46.8

DBSCAN-SWA_106

1482219 : 1482876

Elephant_endotheliotropic_herpesvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000455256.1\|1482219_1482876_-	uracil-DNA glycosylase	U5U4C1	Elephant_endotheliotropic_herpesvirus	1.1e-45	46.4

DBSCAN-SWA_107

1486517 : 1489838

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001100846.1\|1486517_1487894_-	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.1e-20	24.2
WP_173896743.1\|1488437_1489838_-	MFS transporter	Q6JIH2	Burkholderia_virus	9.4e-55	32.8

DBSCAN-SWA_108

1513126 : 1513789

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001067261.1\|1513126_1513789_+	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	1.4e-24	37.4

DBSCAN-SWA_109

1520371 : 1521559

Emiliania_huxleyi_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000250823.1\|1520371_1521559_-	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	4.4e-45	30.6

DBSCAN-SWA_110

1524587 : 1535541

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000090315.1\|1524587_1526669_-	elongation factor G	E4ZFJ7	Streptococcus_phage	2.7e-66	28.3
WP_001137495.1\|1526791_1527262_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_001142337.1\|1527327_1527741_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_000031892.1\|1527838_1528093_-	ribosomal L7Ae/L30e/S12e/Gadd45 family protein	NA	NA	NA	NA
WP_001788197.1\|1528229_1531826_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	3.3e-67	24.6
WP_000918667.1\|1531989_1535541_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	2.1e-50	24.3

DBSCAN-SWA_111

1539223 : 1544006

Bacillus_virus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001288302.1\|1539223_1539772_-	transcription termination/antitermination protein NusG	G3MAW2	Bacillus_virus	8.6e-12	33.5
WP_001074473.1\|1539784_1539967_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_001788193.1\|1540022_1540166_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_000872882.1\|1540280_1540850_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_000664737.1\|1540930_1541455_-	NYN domain-containing protein	NA	NA	NA	NA
WP_000390332.1\|1541454_1542201_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000370182.1\|1542208_1542613_-	Mini-ribonuclease 3	NA	NA	NA	NA
WP_000631969.1\|1542605_1544006_-\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	1.2e-54	31.8

DBSCAN-SWA_112

1550017 : 1552474

Escherichia_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000897132.1\|1550017_1552474_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A1C3S747	Escherichia_phage	1.4e-133	41.2

DBSCAN-SWA_113

1571341 : 1581612

Catovirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001288202.1\|1571341_1572829_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.1e-92	41.1
WP_001790128.1\|1572881_1572974_-	hypothetical protein	NA	NA	NA	NA
WP_000613722.1\|1573367_1573844_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_001154302.1\|1573840_1574206_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_000167944.1\|1574183_1574987_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	3.0e-21	29.0
WP_000057594.1\|1575202_1576135_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	3.7e-108	65.7
WP_000148598.1\|1576313_1577195_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_001167883.1\|1577422_1579516_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	E5EQ50	Micromonas_sp._RCC1109_virus	1.2e-109	42.7
WP_000551283.1\|1579772_1580312_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	6.5e-12	29.8
WP_001176709.1\|1580316_1581612_-\|tRNA	tRNA lysidine(34) synthetase TilS	A0A1V0SI91	Klosneuvirus	4.8e-13	24.5

DBSCAN-SWA_114

1590868 : 1593333

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000933774.1\|1590868_1591834_-	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	6.1e-45	35.4
WP_001252543.1\|1591980_1593333_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L821	Tupanvirus	8.3e-24	30.4

DBSCAN-SWA_115

1599238 : 1602336

Klosneuvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001051136.1\|1599238_1601212_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	3.2e-93	36.0
WP_000279926.1\|1601496_1602336_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.7e-57	45.8

DBSCAN-SWA_116

1606242 : 1606860

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001272126.1\|1606242_1606860_-	dTMP kinase	M1PSC7	Streptococcus_phage	9.2e-47	48.3

DBSCAN-SWA_117

1615721 : 1617419

Streptococcus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001109040.1\|1615721_1617419_-	DNA polymerase III subunit gamma/tau	A0A1U9WR94	Streptococcus_virus	1.9e-54	42.3

DBSCAN-SWA_118

1634067 : 1640307

Lactobacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001170264.1\|1634067_1635072_-	autolysin/adhesin Aaa	A0A0A7NU10	Lactobacillus_phage	1.6e-24	41.2
WP_000825530.1\|1635403_1636246_-	dipeptide ABC transporter glycylmethionine-binding lipoprotein	NA	NA	NA	NA
WP_000467994.1\|1636282_1636942_-	ABC transporter permease	NA	NA	NA	NA
WP_000569281.1\|1636945_1637971_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-32	37.3
WP_001036648.1\|1638266_1639409_-	bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase	NA	NA	NA	NA
WP_000634098.1\|1639401_1640307_-	cysteine synthase family protein	A0A1W6JIM2	Lactococcus_phage	3.8e-49	39.7

DBSCAN-SWA_119

1666253 : 1669014

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000072584.1\|1666253_1667465_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.2e-44	35.2
WP_000028659.1\|1667457_1669014_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.3e-288	99.4

DBSCAN-SWA_120

1681551 : 1687000

Paenibacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000159787.1\|1681551_1681824_+\|transposase	transposase	A0A0C5AJ30	Paenibacillus_phage	1.3e-13	50.6
WP_000041880.1\|1682222_1682927_+	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	5.8e-29	37.1
WP_000551643.1\|1683318_1683855_+	hypothetical protein	NA	NA	NA	NA
WP_000424963.1\|1683967_1685509_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
WP_000264071.1\|1685533_1687000_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5

DBSCAN-SWA_121

1695960 : 1697484

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000930514.1\|1695960_1697484_+	alkyl hydroperoxide reductase subunit F	A0A249XZT7	Enterococcus_phage	1.4e-40	33.6

DBSCAN-SWA_122

1705798 : 1712127

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000934799.1\|1705798_1706302_-	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	1.2e-60	74.7
WP_001261460.1\|1706322_1706619_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_001052484.1\|1706862_1707054_+	hypothetical protein	U3PCX8	Staphylococcus_phage	1.1e-22	80.0
WP_001218732.1\|1707139_1708237_-	redox-regulated ATPase YchF	NA	NA	NA	NA
WP_000157348.1\|1708248_1708452_-	DUF951 domain-containing protein	NA	NA	NA	NA
WP_000373073.1\|1708481_1709363_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_001557587.1\|1709516_1710362_-	ParB/RepB/Spo0J family partition protein	A0A1C9EHW0	Gordonia_phage	1.6e-12	34.4
WP_000655692.1\|1711023_1712127_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A0B5JD48	Pandoravirus	3.9e-11	28.0

DBSCAN-SWA_123

1722065 : 1722908

Anomala_cuprea_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000209551.1\|1722065_1722908_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.8e-11	27.2

DBSCAN-SWA_124

1744217 : 1746952

Bodo_saltans_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000280799.1\|1744217_1745240_-	lipoate--protein ligase	A0A2H4UVX5	Bodo_saltans_virus	6.7e-10	30.4
WP_001191954.1\|1745217_1746162_-	NAD-dependent deacetylase	NA	NA	NA	NA
WP_000449069.1\|1746151_1746952_-	protein-ADP-ribose hydrolase	A0A2K9L8X2	Tupanvirus	5.8e-41	43.4

DBSCAN-SWA_125

1765189 : 1765867

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000911017.1\|1765189_1765867_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-31	38.9

DBSCAN-SWA_126

1778407 : 1782847

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000549287.1\|1778407_1782847_-	type VII secretion protein EssC	V5UPA0	Mycobacterium_phage	6.3e-28	25.6

DBSCAN-SWA_127

1793452 : 1795114

Amsacta_moorei_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000570070.1\|1793452_1794112_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.6e-23	37.2
WP_000736784.1\|1794163_1795114_-	glycine-glycine endopeptidase LytM	V5R8R0	Arthrobacter_phage	1.5e-16	42.7

DBSCAN-SWA_128

1803802 : 1805239

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000164003.1\|1803802_1805239_-	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	1.1e-29	25.7

DBSCAN-SWA_129

1808999 : 1813538

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000950281.1\|1808999_1810754_-	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	9.0e-63	31.5
WP_000608818.1\|1810998_1811673_-	iron-sulfur cluster repair di-iron protein ScdA	NA	NA	NA	NA
WP_000975351.1\|1811816_1813538_-	poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase	A0A1V0SAH6	Catovirus	2.1e-11	37.4

DBSCAN-SWA_130

1822865 : 1823909

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000645608.1\|1822865_1823909_-	galactitol-1-phosphate 5-dehydrogenase	E3SJ82	Synechococcus_phage	3.5e-14	24.9

DBSCAN-SWA_131

1831123 : 1832653

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000838205.1\|1831123_1832653_+	PTS transporter subunit EIIC	A0A2I7SAJ6	Vibrio_phage	4.5e-10	50.7

DBSCAN-SWA_132

1841528 : 1843034

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001008400.1\|1841528_1843034_+	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.0e-39	25.9

DBSCAN-SWA_133

1854141 : 1859500

Tetraselmis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000894660.1\|1854141_1856391_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.7e-186	45.1
WP_000837116.1\|1856978_1857947_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_000127990.1\|1857943_1859500_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	5.8e-13	27.2

DBSCAN-SWA_134

1869710 : 1871770

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000818915.1\|1869710_1870808_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	1.4e-24	35.6
WP_000166920.1\|1871191_1871770_-	M23 family metallopeptidase	A0A2K9VGT1	Pontimonas_phage	9.7e-14	39.1

DBSCAN-SWA_135

1880319 : 1883507

Planktothrix_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000067352.1\|1880319_1881912_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.1e-22	33.6
WP_000794565.1\|1882421_1882619_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	2.1e-05	43.3
WP_000960712.1\|1882784_1883507_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-22	34.8

DBSCAN-SWA_136

1887379 : 1888060

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000571407.1\|1887379_1888060_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.9e-33	37.0

DBSCAN-SWA_137

1904865 : 1906050

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001084442.1\|1904865_1906050_+	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	2.0e-34	28.9

DBSCAN-SWA_138

1910886 : 1921170

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000605281.1\|1910886_1918062_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	4.5e-68	29.7
WP_000826861.1\|1918508_1919759_-	MFS transporter	NA	NA	NA	NA
WP_000706135.1\|1920144_1921170_-	NAD-dependent formate dehydrogenase	A0A1V0SBV6	Catovirus	8.5e-29	33.5

DBSCAN-SWA_139

1924706 : 1927878

Bacillus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000590854.1\|1924706_1925447_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.5e-38	40.1
WP_000171919.1\|1925788_1926301_-	DUF4242 domain-containing protein	NA	NA	NA	NA
WP_173896752.1\|1926479_1926683_+	hypothetical protein	NA	NA	NA	NA
WP_001013485.1\|1926918_1927878_-	cation transporter	A0A1V0SED0	Indivirus	1.2e-11	34.2

DBSCAN-SWA_140

1931219 : 1933704

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000723436.1\|1931219_1932365_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	4.6e-23	25.9
WP_000779504.1\|1932441_1933704_-	nucleotide sugar dehydrogenase	A0A127AXI2	Bacillus_phage	4.3e-22	25.5

DBSCAN-SWA_141

1940539 : 1947104

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000413171.1\|1940539_1941664_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SJE0	Klosneuvirus	6.7e-128	59.6
WP_001028283.1\|1941667_1942777_-	capsular polysaccharide biosynthesis protein CapF	NA	NA	NA	NA
WP_000459062.1\|1942789_1943818_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	1.1e-41	35.3
WP_000940790.1\|1943807_1945631_-	polysaccharide biosynthesis protein	A0A1V0SAI8	Catovirus	5.2e-29	29.1
WP_000565304.1\|1945650_1946415_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_000037332.1\|1946417_1947104_-	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	3.7e-28	36.1

DBSCAN-SWA_142

1951124 : 1952300

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000469833.1\|1951124_1952300_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	2.0e-29	27.6

DBSCAN-SWA_143

1957739 : 1958513

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000078092.1\|1957739_1958513_+	phosphonate ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-13	26.1

DBSCAN-SWA_144

1966544 : 1967144

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000874681.1\|1966544_1967144_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	7.6e-54	50.2

DBSCAN-SWA_145

1972081 : 1977178

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001793242.1\|1972081_1973062_-	NAD-dependent epimerase/dehydratase family protein	A0A1V0SAI6	Catovirus	1.0e-47	37.0
WP_001789407.1\|1973131_1973254_-	hypothetical protein	NA	NA	NA	NA
WP_000183771.1\|1973397_1974174_-	(S)-acetoin forming diacetyl reductase	NA	NA	NA	NA
WP_000414629.1\|1974385_1975012_-	MFS transporter	NA	NA	NA	NA
WP_001015549.1\|1975207_1975972_-	bifunctional transcriptional regulator/O-phospho-L-serine synthase SbnI	NA	NA	NA	NA
WP_001223713.1\|1975975_1977178_-	staphyloferrin B biosynthesis decarboxylase SbnH	A0A2K9L4I2	Tupanvirus	3.9e-09	21.1

DBSCAN-SWA_146

1985444 : 1989654

Lactococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000570808.1\|1985444_1986425_-	2,3-diaminopropionate biosynthesis protein SbnA	A0A1W6JHY1	Lactococcus_phage	2.1e-40	35.6
WP_001045111.1\|1986655_1987648_+	staphyloferrin B ABC transporter substrate-binding protein SirA	NA	NA	NA	NA
WP_000924990.1\|1987663_1988659_+	staphyloferrin B ABC transporter permease subunit SirB	NA	NA	NA	NA
WP_000136633.1\|1988655_1989654_+	staphyloferrin B ABC transporter permease subunit SirC	A0A2H4IY97	uncultured_Caudovirales_phage	5.2e-15	27.8

DBSCAN-SWA_147

2022756 : 2023821

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000816133.1\|2022756_2023821_-	persulfide response sulfurtransferase CstA	A0A2H4PQR9	Staphylococcus_phage	7.7e-09	41.8

DBSCAN-SWA_148

2034509 : 2041163

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000852430.1\|2034509_2036531_-	K(+)-transporting ATPase subunit B	E4ZFI9	Streptococcus_phage	6.6e-41	29.0
WP_000029430.1\|2036549_2038226_-	potassium-transporting ATPase subunit A	NA	NA	NA	NA
WP_000631574.1\|2038246_2038327_-	K(+)-transporting ATPase subunit F	NA	NA	NA	NA
WP_000446429.1\|2038493_2041163_+	sensor histidine kinase KdpD	A0A2K9L0Z8	Tupanvirus	6.0e-10	21.5

DBSCAN-SWA_149

2048945 : 2050295

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000815646.1\|2048945_2050295_+	recombinase family protein	Q9T200	Bacillus_phage	1.4e-18	25.1

DBSCAN-SWA_150

2056030 : 2057233

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001631029.1\|2056030_2057233_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	6.2e-39	34.5

DBSCAN-SWA_151

2060963 : 2070973

Bacillus_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000088649.1\|2060963_2061764_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.0e-37	35.9
WP_001104165.1\|2062152_2062941_-	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_001060140.1\|2062941_2064276_-	hypothetical protein	NA	NA	NA	NA
WP_000871607.1\|2064268_2066095_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.6e-30	31.3
WP_000101976.1\|2066107_2066809_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-42	39.2
WP_000095328.1\|2068011_2069295_-	adenylosuccinate synthase	L7Y4J5	Megavirus	1.8e-68	34.6
WP_000375647.1\|2069572_2070973_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	5.4e-111	48.1

DBSCAN-SWA_152

2077663 : 2086709

Bacillus_virus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000884332.1\|2077663_2078950_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.5e-88	50.9
WP_000177465.1\|2079328_2080843_-	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.2e-90	38.4
WP_000449218.1\|2081168_2081981_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_000819059.1\|2082068_2084738_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	3.6e-119	35.9
WP_000255578.1\|2084774_2086709_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	5.7e-143	44.9

DBSCAN-SWA_153

2096809 : 2103366

Faecalibacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000742837.1\|2096809_2097649_+	nucleoid occlusion protein	A0A2K9V477	Faecalibacterium_phage	2.2e-06	23.8
WP_000491382.1\|2098099_2098453_+	DUF3147 family protein	NA	NA	NA	NA
WP_000779134.1\|2098520_2098916_+	DUF3147 family protein	NA	NA	NA	NA
WP_001054128.1\|2099175_2099745_+	helix-turn-helix transcriptional regulator	D2XQ11	Bacillus_virus	6.2e-05	33.3
WP_001059079.1\|2099862_2100063_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.4e-19	69.8
WP_000672033.1\|2100454_2100646_-	peptide resistance ABC transporter activity modulator VraH	NA	NA	NA	NA
WP_000143647.1\|2100737_2102618_-	peptide resistance ABC transporter permease subunit VraE	NA	NA	NA	NA
WP_000154162.1\|2102607_2103366_-	peptide resistance ABC transporter ATP-binding subunit VraD	G9BWD6	Planktothrix_phage	9.0e-36	39.5

DBSCAN-SWA_154

2117619 : 2119332

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000138654.1\|2117619_2119332_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-20	32.3

DBSCAN-SWA_155

2124960 : 2125974

Faustovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000639184.1\|2124960_2125974_+	histidinol-phosphate aminotransferase family protein	A0A1X7QHI1	Faustovirus	9.6e-09	25.9

DBSCAN-SWA_156

2138311 : 2139004

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000185863.1\|2138311_2139004_+	polysaccharide biosynthesis tyrosine autokinase	A0A1X9I5D6	Streptococcus_phage	2.2e-28	38.0

DBSCAN-SWA_157

2165102 : 2166962

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001125628.1\|2165102_2166962_-	amidase domain-containing protein	A0A249Y0X5	Enterococcus_phage	9.7e-15	37.3

DBSCAN-SWA_158

2192645 : 2194396

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000143425.1\|2192645_2193533_+	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Q8QNA2	Ectocarpus_siliculosus_virus	2.5e-05	22.5
WP_000923760.1\|2193640_2194396_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-31	37.9

DBSCAN-SWA_159

2197816 : 2198314

Canarypox_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001065268.1\|2197816_2198314_+	glutathione peroxidase	Q6VZR0	Canarypox_virus	1.8e-21	33.1

DBSCAN-SWA_160

2203308 : 2205692

Enterococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001071729.1\|2203308_2205159_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	9.3e-236	64.3
WP_000173331.1\|2205155_2205692_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	3.9e-41	48.0

DBSCAN-SWA_161

2210570 : 2220684

Klosneuvirus(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000066521.1\|2210570_2212280_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	3.8e-58	32.3
WP_000011688.1\|2212557_2212770_+	hypothetical protein	NA	NA	NA	NA
WP_001028775.1\|2213049_2213493_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_001172341.1\|2213686_2215285_+	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	5.3e-78	36.8
WP_001791980.1\|2215344_2215674_-	hypothetical protein	NA	NA	NA	NA
WP_001130051.1\|2215969_2217466_+	malate dehydrogenase (quinone)	NA	NA	NA	NA
WP_001031409.1\|2217659_2218550_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	1.2e-07	29.2
WP_001237629.1\|2218672_2219089_-	hypothetical protein	NA	NA	NA	NA
WP_000030069.1\|2219346_2220684_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	8.8e-18	26.4

DBSCAN-SWA_162

2251017 : 2254806

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000751263.1\|2251017_2251719_+	lytic transglycosylase IsaA	Q4Z8Z7	Staphylococcus_phage	5.2e-38	46.4
WP_000379821.1\|2252994_2254806_+	acetyltransferase	A0A1R3Y5Q6	Salmonella_virus	1.3e-35	31.5

DBSCAN-SWA_163

2263240 : 2267355

Acanthocystis_turfacea_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161369.1\|2263240_2264239_+	D-lactate dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	1.0e-34	30.2
WP_000076661.1\|2264329_2264536_-	copper chaperone CopZ	NA	NA	NA	NA
WP_000024139.1\|2264946_2267355_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	3.2e-127	40.8

DBSCAN-SWA_164

2276596 : 2279632

Enterobacteria_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001058993.1\|2276596_2278702_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpL	H6X3M6	Enterobacteria_phage	3.1e-118	38.5
WP_000455988.1\|2279110_2279632_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	2.0e-26	41.1

DBSCAN-SWA_165

2286058 : 2292442

Yellowstone_lake_phycodnavirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001062663.1\|2286058_2287798_+	pyruvate oxidase	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.0e-35	24.1
WP_000473679.1\|2288098_2290165_+	PTS transporter subunit EIIC	A0A2I7SAJ6	Vibrio_phage	8.3e-07	43.3
WP_000206031.1\|2290544_2290955_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_000240663.1\|2290996_2291353_+	thioredoxin family protein	NA	NA	NA	NA
WP_001228167.1\|2291473_2292442_+	alpha/beta hydrolase	A0A167RJ59	Powai_lake_megavirus	4.0e-12	26.5

DBSCAN-SWA_166

2301731 : 2302724

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000161545.1\|2301731_2302724_-	D-lactate dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	3.7e-37	32.7

DBSCAN-SWA_167

2312004 : 2312700

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000538625.1\|2312004_2312700_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.0e-38	37.6

DBSCAN-SWA_168

2331492 : 2332359

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000721336.1\|2331492_2332359_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	1.3e-78	52.6

DBSCAN-SWA_169

2340160 : 2345356

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075339662.1\|2340160_2341969_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	6.6e-93	37.3
WP_000755947.1\|2342100_2342493_+	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
WP_000088733.1\|2342494_2345356_+	DUF3427 domain-containing protein	Q5YA94	Bacillus_phage	3.1e-28	27.9

DBSCAN-SWA_170

2353198 : 2353894

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000217456.1\|2353198_2353894_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	4.3e-08	35.6

DBSCAN-SWA_171

2358448 : 2359267

Acanthamoeba_polyphaga_moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000824948.1\|2358448_2359267_+	SDR family oxidoreductase	L7RG25	Acanthamoeba_polyphaga_moumouvirus	1.3e-08	27.2

DBSCAN-SWA_172

2367319 : 2368877

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000173871.1\|2367319_2368135_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.8e-13	29.8
WP_000598772.1\|2368127_2368877_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	9.0e-20	32.7

DBSCAN-SWA_173

2376148 : 2380577

Organic_Lake_phycodnavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000923526.1\|2376148_2376811_+	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	5.5e-21	30.8
WP_000072149.1\|2376803_2377580_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_000026189.1\|2377975_2379163_+	MFS transporter	NA	NA	NA	NA
WP_000700925.1\|2379224_2380577_-	carboxylesterase/lipase family protein	A0A0B5J865	Pandoravirus	2.5e-12	34.2

DBSCAN-SWA_174

2383971 : 2385830

Mycoplasma_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000948974.1\|2383971_2385198_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.6e-20	50.5
WP_000569120.1\|2385194_2385830_+	ABC transporter permease	G3M9Y4	Bacillus_virus	9.0e-05	26.2

DBSCAN-SWA_175

2403557 : 2409819

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001176863.1\|2403557_2404700_-	glycerate kinase	W6LM47	Streptococcus_phage	5.3e-56	44.3
WP_000779360.1\|2404967_2405354_+	flippase GtxA	NA	NA	NA	NA
WP_000482652.1\|2405487_2405595_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_001064825.1\|2406297_2408061_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.5e-36	24.7
WP_000486487.1\|2408085_2409819_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.0e-31	25.7

DBSCAN-SWA_176

2413280 : 2419050

Staphylococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000971550.1\|2413280_2414396_+	pyridoxal phosphate-dependent aminotransferase family protein	V5LQ39	Emiliania_huxleyi_virus	1.6e-20	24.7
WP_000286875.1\|2414406_2415099_+	6-carboxyhexanoate--CoA ligase	NA	NA	NA	NA
WP_000200956.1\|2415109_2415577_+	hypothetical protein	NA	NA	NA	NA
WP_000783428.1\|2415628_2416606_-	bi-component gamma-hemolysin HlgAB/HlgCB subunit B	A0A2H4PQH7	Staphylococcus_phage	7.1e-142	76.2
WP_000916704.1\|2416607_2417555_-	bi-component gamma-hemolysin HlgCB subunit C	A0A2I6PER8	Staphylococcus_phage	3.2e-139	77.5
WP_000594519.1\|2418120_2419050_-	bi-component gamma-hemolysin HlgAB subunit A	A0A2H4PQI5	Staphylococcus_phage	3.2e-120	71.1

DBSCAN-SWA_177

2427106 : 2427838

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000615461.1\|2427106_2427838_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.1e-25	34.7

DBSCAN-SWA_178

2444487 : 2446047

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000692648.1\|2444487_2446047_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	4.4e-21	46.8

DBSCAN-SWA_179

2467314 : 2468349

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000655971.1\|2467314_2468349_+	NAD(P)/FAD-dependent oxidoreductase	G3MA85	Bacillus_virus	5.8e-17	26.6

DBSCAN-SWA_180

2478194 : 2482091

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000477338.1\|2478194_2479568_-	heme sensor histidine kinase HssS	A0A1V0SGX0	Hokovirus	2.3e-13	29.8
WP_000249497.1\|2479560_2480235_-	DNA-binding heme response regulator HssR	W8CYM9	Bacillus_phage	3.6e-52	45.2
WP_000761395.1\|2480370_2481426_+	ABC transporter permease	NA	NA	NA	NA
WP_001229920.1\|2481425_2482091_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-36	38.8

DBSCAN-SWA_181

2485827 : 2487036

Salmonella_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000999131.1\|2485827_2487036_+	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	3.9e-33	26.3

DBSCAN-SWA_182

2499127 : 2500027

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000524830.1\|2499127_2500027_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.2e-15	28.7

DBSCAN-SWA_183

2507399 : 2507819

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000920239.1\|2507399_2507819_-	FosB1/FosB3 family fosfomycin resistance bacillithiol transferase	Q2LI91	Bacillus_phage	2.6e-37	61.9

DBSCAN-SWA_184

2513499 : 2514381

Diadromus_pulchellus_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000235289.1\|2513499_2514381_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.8e-62	46.3

DBSCAN-SWA_185

2522259 : 2522895

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000285450.1\|2522259_2522895_+	HAD family hydrolase	A7J6N1	Paramecium_bursaria_Chlorella_virus	1.6e-09	27.1

DBSCAN-SWA_186

2535700 : 2539818

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000739224.1\|2535700_2536477_+	glucosaminidase domain-containing protein	H9A0P7	Staphylococcus_phage	3.8e-37	41.0
WP_000684147.1\|2536787_2537912_+	FAD-dependent monooxygenase	A0A2K9L3K5	Tupanvirus	9.3e-13	22.8
WP_000417018.1\|2538003_2538957_-	2-hydroxyacid dehydrogenase	A0A1V0SBV6	Catovirus	6.4e-31	28.9
WP_000737705.1\|2539317_2539818_-	CHAP domain-containing protein	A0A2R3ZXQ4	Staphylococcus_phage	2.0e-07	39.3

DBSCAN-SWA_187

2543735 : 2544539

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000717381.1\|2543735_2544539_-	CHAP domain-containing protein	A0A2R3ZXQ4	Staphylococcus_phage	9.3e-07	41.3

DBSCAN-SWA_188

2563519 : 2564125

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000913024.1\|2563519_2564125_+	ATP-binding cassette domain-containing protein	W5SAS9	Pithovirus	4.3e-12	30.1

DBSCAN-SWA_189

2576095 : 2579263

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000592307.1\|2576095_2579263_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.1e-61	21.8

DBSCAN-SWA_190

2602946 : 2604613

Anomala_cuprea_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000389658.1\|2602946_2603756_+	energy-coupling factor transporter ATPase	W6JKT0	Anomala_cuprea_entomopoxvirus	1.7e-19	30.0
WP_000155387.1\|2603752_2604613_+	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	9.7e-10	23.9

DBSCAN-SWA_191

2613392 : 2621048

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000411031.1\|2613392_2614409_+	RNA-directed DNA polymerase	Q7M2A9	Enterobacteria_phage	1.0e-18	29.7
WP_000655241.1\|2614982_2615165_+	hypothetical protein	NA	NA	NA	NA
WP_000130149.1\|2615658_2617323_+	acetolactate synthase AlsS	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	8.0e-45	25.9
WP_000186134.1\|2617359_2618064_+	acetolactate decarboxylase	NA	NA	NA	NA
WP_000769705.1\|2618447_2618873_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000044362.1\|2619167_2619983_+	HAD-IIB family hydrolase	NA	NA	NA	NA
WP_001044441.1\|2620193_2621048_+	M23 family metallopeptidase	E5G070	Clostridium_phage	4.9e-06	37.9

DBSCAN-SWA_192

2624430 : 2626740

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001015500.1\|2624430_2625279_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.0e-44	39.2
WP_000875476.1\|2625511_2625715_+	hypothetical protein	NA	NA	NA	NA
WP_001791678.1\|2625801_2625963_-	hypothetical protein	NA	NA	NA	NA
WP_001557494.1\|2625999_2626740_-	NAD-dependent protein deacylase	A0A2I2L319	Orpheovirus	1.5e-14	29.9

DBSCAN-SWA_193

2633060 : 2634473

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000169224.1\|2633060_2634473_+	6-phospho-beta-galactosidase	A0A0B5JD41	Pandoravirus	3.0e-48	28.9

DBSCAN-SWA_194

2638436 : 2639999

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000792342.1\|2638436_2639999_+	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.2e-18	24.6

DBSCAN-SWA_195

2650201 : 2651170

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000989088.1\|2650201_2651170_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.0e-15	28.8

DBSCAN-SWA_196

2667102 : 2668011

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167867.1\|2667102_2668011_+	arginase	A0A1V0SJM8	Klosneuvirus	3.2e-27	32.0

DBSCAN-SWA_197

2671602 : 2679048

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001048259.1\|2671602_2679048_+	DUF1542 domain-containing protein	A0A2H4PQU6	Staphylococcus_phage	3.9e-22	31.5

DBSCAN-SWA_198

2685304 : 2688124

Paramecium_bursaria_Chlorella_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000334463.1\|2685304_2687110_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	5.2e-98	38.8
WP_000908182.1\|2687341_2688124_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.3e-09	30.1

DBSCAN-SWA_199

2699304 : 2703135

Clostridium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000070866.1\|2699304_2699748_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	5.6e-38	53.7
WP_000160304.1\|2699868_2700579_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_001083318.1\|2700892_2701555_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_001242311.1\|2701833_2703135_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	3.6e-133	58.9

DBSCAN-SWA_200

2711075 : 2712686

Only_Syngen_Nebraska_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000159960.1\|2711075_2712686_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.7e-146	49.6

DBSCAN-SWA_201

2720489 : 2728239

Bacillus_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000273358.1\|2720489_2721089_+	thymidine kinase	G3MBK1	Bacillus_virus	6.2e-32	42.9
WP_000460242.1\|2721089_2722166_+	peptide chain release factor 1	NA	NA	NA	NA
WP_000248732.1\|2722152_2722989_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_000379895.1\|2723072_2724119_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	2.2e-40	35.3
WP_000697334.1\|2724115_2724535_+	low molecular weight protein arginine phosphatase	NA	NA	NA	NA
WP_000654184.1\|2724641_2725166_+	TIGR01440 family protein	NA	NA	NA	NA
WP_000120494.1\|2725192_2726431_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	8.2e-103	53.0
WP_000048712.1\|2726458_2727088_+	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_000723418.1\|2727111_2728239_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.0e-27	29.9

DBSCAN-SWA_202

2738642 : 2739038

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000932694.1\|2738642_2739038_+	single-stranded DNA-binding protein	A0A1J0MFK5	Staphylococcus_phage	1.3e-14	38.5

DBSCAN-SWA_203

2745309 : 2745957

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001187630.1\|2745309_2745957_-	HD domain-containing protein	H2ED17	Moumouvirus	8.0e-09	27.0

DBSCAN-SWA_204

2753157 : 2754678

Diachasmimorpha_longicaudata_entomopoxvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001178942.1\|2753157_2754678_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.0e-58	33.9

DBSCAN-SWA_205

2761868 : 2763896

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173896767.1\|2761868_2763896_+	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	1.7e-25	23.5

DBSCAN-SWA_206

2769045 : 2772430

Clostridium_botulinum_C_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000621175.1\|2769045_2769408_+	type II toxin-antitoxin system PemK/MazF family toxin	Q332J9	Clostridium_botulinum_C_phage	4.2e-07	32.8
WP_000390827.1\|2769757_2770759_+	PP2C family protein-serine/threonine phosphatase	NA	NA	NA	NA
WP_001052491.1\|2770877_2771204_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_001190829.1\|2771205_2771685_+	anti-sigma B factor RsbW	NA	NA	NA	NA
WP_001041111.1\|2771659_2772430_+	RNA polymerase sigma factor SigB	A0A0A0RNH9	Bacillus_phage	2.2e-21	34.9

DBSCAN-SWA_207

2786548 : 2791272

Micromonas_sp._RCC1109_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000094583.1\|2786548_2788078_-	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	5.5e-08	28.1
WP_072399972.1\|2788107_2789127_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_000196911.1\|2789248_2789503_-	ACT domain-containing protein	NA	NA	NA	NA
WP_000047812.1\|2789502_2791272_-	biosynthetic-type acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	9.1e-63	30.6

DBSCAN-SWA_208

2795032 : 2809093

Moraxella_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000159042.1\|2795032_2796058_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.4e-62	40.6
WP_000106332.1\|2796372_2797983_-	MutS family DNA mismatch repair protein	A0A0N9R0S5	Chrysochromulina_ericina_virus	1.9e-19	28.1
WP_001792272.1\|2798071_2798200_+	hypothetical protein	NA	NA	NA	NA
WP_000602057.1\|2798344_2800273_-	ABC-F type ribosomal protection protein	A0A2K9L0W2	Tupanvirus	9.3e-53	30.2
WP_001283612.1\|2800525_2801161_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_000266884.1\|2801464_2802544_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_000581076.1\|2802603_2802828_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_001052270.1\|2803035_2804286_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	4.5e-40	31.2
WP_000790331.1\|2804468_2805419_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000141432.1\|2805567_2807052_+	glycoside hydrolase family 32 protein	S6ATV4	Bacillus_phage	2.3e-19	26.5
WP_001253312.1\|2807048_2808008_+	carbohydrate kinase	NA	NA	NA	NA
WP_000688492.1\|2808376_2809093_-	response regulator transcription factor	A0A2H4J4Z6	uncultured_Caudovirales_phage	2.3e-25	32.6

DBSCAN-SWA_209

2816274 : 2818251

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000917289.1\|2816274_2816559_+	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000240642.1\|2816634_2818251_+	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7

DBSCAN-SWA_210

2822200 : 2842835

Staphylococcus_phage(94.87%)

integrase

attL 2819042:2819056|attR 2826679:2826693

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2819042:2819056	attL	NA	NA	NA	NA
WP_000791411.1\|2822200_2823256_+	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
WP_000595392.1\|2823277_2824294_+	bi-component leukocidin LukGH subunit G	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
WP_000857200.1\|2825412_2826450_-\|integrase	site-specific integrase	Q38086	Staphylococcus_phage	2.2e-178	99.7
WP_001549185.1\|2826640_2827354_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1X9H026	Staphylococcus_phage	5.0e-129	100.0
2826679:2826693	attR	NA	NA	NA	NA
WP_000705245.1\|2827432_2827615_-	hypothetical protein	A0A0H3U4Z4	Staphylococcus_phage	6.9e-27	96.7
WP_000109189.1\|2827685_2827871_-	hypothetical protein	U5U7D6	Staphylococcus_phage	2.3e-25	100.0
WP_000345949.1\|2827867_2828014_-	hypothetical protein	A0A1X9H032	Staphylococcus_phage	3.3e-19	100.0
WP_001557601.1\|2828087_2828942_-	restriction endonuclease	A0A1X9H037	Staphylococcus_phage	7.3e-151	100.0
WP_001083975.1\|2828953_2829670_-	helix-turn-helix domain-containing protein	A0A1X9H038	Staphylococcus_phage	5.4e-131	100.0
WP_000639923.1\|2829833_2830076_+	DUF739 family protein	A0A1X9H035	Staphylococcus_phage	1.6e-39	100.0
WP_000435360.1\|2830088_2830532_+	hypothetical protein	W5R971	Staphylococcus_phage	1.5e-75	100.0
WP_000939495.1\|2830546_2830687_+	hypothetical protein	A0A2I6PDT8	Staphylococcus_phage	1.9e-16	100.0
WP_000772137.1\|2830679_2830889_-	hypothetical protein	A0A2I6PDR8	Staphylococcus_phage	9.1e-31	100.0
WP_001148338.1\|2830945_2831695_+	phage antirepressor KilAC domain-containing protein	B7T097	Staphylococcus_virus	3.4e-136	99.6
WP_001148862.1\|2831710_2831908_+	hypothetical protein	O80075	Staphylococcus_phage	3.5e-24	87.7
WP_000762521.1\|2831894_2832275_-	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
WP_001120201.1\|2832329_2832653_+	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
WP_000048129.1\|2832649_2832811_+	DUF1270 family protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
WP_001810307.1\|2832905_2833193_+	DUF2482 family protein	A0A1P8L6F8	Staphylococcus_phage	7.1e-42	100.0
WP_000291510.1\|2833213_2833474_+	DUF1108 family protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
WP_001205732.1\|2833482_2833746_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000700554.1\|2833754_2835698_+	AAA family ATPase	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	100.0
WP_000180600.1\|2835699_2836620_+	recombinase RecT	A0A1P8L6F6	Staphylococcus_phage	5.1e-166	100.0
WP_064135358.1\|2836700_2837318_+	MBL fold metallo-hydrolase	A0A1P8L6F7	Staphylococcus_phage	1.2e-86	100.0
WP_000934759.1\|2837318_2837789_+	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
WP_000148333.1\|2837818_2838712_+	DnaD domain-containing protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
WP_000338528.1\|2838718_2838937_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000401969.1\|2838945_2839350_+	RusA family crossover junction endodeoxyribonuclease	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
WP_000101279.1\|2839362_2839734_+	hypothetical protein	A0A2I6PDG3	Staphylococcus_phage	1.4e-50	91.1
WP_000111491.1\|2839733_2839991_+	DUF3310 domain-containing protein	A0A1X9H067	Staphylococcus_phage	6.3e-42	98.8
WP_000178987.1\|2839987_2840236_+	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	7.5e-40	96.3
WP_001065108.1\|2840250_2840496_+	DUF1024 family protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
WP_000185693.1\|2840492_2841029_+	dUTP diphosphatase	Q9MBR0	Staphylococcus_prophage	1.6e-95	100.0
WP_001282077.1\|2841065_2841311_+	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	2.5e-35	98.8
WP_000195784.1\|2841307_2841514_+	DUF1381 domain-containing protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
WP_000595265.1\|2841510_2841660_+	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_001557462.1\|2841659_2841860_+	DUF1514 family protein	D2JLD9	Staphylococcus_phage	5.3e-28	98.5
WP_000590122.1\|2841887_2842304_+	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_000988332.1\|2842535_2842835_+	HNH endonuclease	A0A2I6PDH9	Staphylococcus_phage	3.5e-52	100.0

Anti-CRISPR protein detection

Acr_ID: NZ_CP053640.1|WP_000437472.1|1058267_1058534_-|phosphocarrier-protein-HPr

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_CP053640.1|WP_000437472.1|1058267_1058534_-|phosphocarrier-protein-HPr

1058267_1058534_-

88 aa aa

1056076-1126434

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_CP053640_7	Orphan	7.1\|2570652\|31\|NZ_CP053640\|CRISPRCasFinder	2570652-2570682	31	1080526-1080556	2

1. spacer 7.1|2570652|31|NZ_CP053640|CRISPRCasFinder matches to NZ_CP053640 position: 1080526-1080556, mismatch: 2

agctgacagaaagtcagcttacaataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
*******..**********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053640

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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