CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP038517	Bacillus altitudinis strain SCU11 chromosome, complete genome	2 crisprs	csa3,DEDDh,WYL,DinG,cas3	0	0	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP038517_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038517_1

251856-251944

Orphan

Consensus_repeat	Method
AGACCTTCACCCTTGTGAAGGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038517_1

>merge|NZ_CP038517|1|251856-251944|CRISPRCasFinder
AGACCTTCACCCTTGTGAAGGTTTCAGCGTGTAGACAAACCCTCGCATTCGGTGTCAGTAATCTGAGACCTTCACCCTTGTGAAGGTTT

>NZ_CP038517|1|1|251856-251944|CRISPRCasFinder
AGACCTTCACCCTTGTGAAGGTTT	CAGCGTGTAGACAAACCCTCGCATTCGGTGTCAGTAATCTG
AGACCTTCACCCTTGTGAAGGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038517.1\|WP_008342143.1\|260958_261888_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NZ_CP038517.1\|WP_017366549.1\|262901_263603_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NZ_CP038517.1\|WP_017366544.1\|250002_251385_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129987
NZ_CP038517.1\|WP_017366541.1\|245783_246347_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP038517.1\|WP_008342149.1\|257179_258118_+\|DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|378022
NZ_CP038517.1\|WP_017366546.1\|258311_259403_+\|SEC-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|225855
NZ_CP038517.1\|WP_017366542.1\|246427_247450_+\|quercetin-2,3-dioxygenase	unknown	unknown	gnl\|CDD\|380345
NZ_CP038517.1\|WP_008342155.1\|251485_251851_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319899
NZ_CP038517.1\|WP_017366545.1\|254390_255371_-\|glutaminase	unknown	unknown	gnl\|CDD\|237074
NZ_CP038517.1\|WP_007498406.1\|247727_248165_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NZ_CP038517.1\|WP_169476117.1\|255936_257175_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|214643
NZ_CP038517.1\|WP_017366538.1\|241878_242415_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|377233
NZ_CP038517.1\|WP_008342164.1\|241557_241764_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038517.1\|WP_008342154.1\|252029_252890_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_CP038517.1\|WP_017366543.1\|248427_249936_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|235730
NZ_CP038517.1\|WP_017366539.1\|242451_244083_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173803
NZ_CP038517.1\|WP_017366548.1\|261924_262890_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|225827
NZ_CP038517.1\|WP_017358609.1\|252929_254357_-\|alanine:cation-symporter-family-protein	unknown	unknown	gnl\|CDD\|376500
NZ_CP038517.1\|WP_017366547.1\|259451_260492_-\|DUF4352-domain-containing-protein	unknown	unknown	gnl\|CDD\|374999
NZ_CP038517.1\|WP_017366540.1\|244253_245738_+\|amidase	unknown	unknown	gnl\|CDD\|180608

Protein	Function_ID	Function_description	E-value
NZ_CP038517.1\|WP_008342143.1\|260958_261888_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.84939e-173
NZ_CP038517.1\|WP_017366549.1\|262901_263603_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	4.51212e-53
NZ_CP038517.1\|WP_017366544.1\|250002_251385_+\|amino-acid-permease	gnl\|CDD\|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	7.91123e-132
NZ_CP038517.1\|WP_017366541.1\|245783_246347_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.43384e-16
NZ_CP038517.1\|WP_008342149.1\|257179_258118_+\|DNA-binding-domain-containing-protein	gnl\|CDD\|378022	pfam08664, YcbB, YcbB domain. YcbB is a DNA-binding domain.	4.22911e-60
NZ_CP038517.1\|WP_017366546.1\|258311_259403_+\|SEC-C-domain-containing-protein	gnl\|CDD\|225855	COG3318, COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA [General function prediction only].	3.15927e-17
NZ_CP038517.1\|WP_017366542.1\|246427_247450_+\|quercetin-2,3-dioxygenase	gnl\|CDD\|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	7.16037e-41
NZ_CP038517.1\|WP_008342155.1\|251485_251851_+\|VOC-family-protein	gnl\|CDD\|319899	cd06588, PhnB_like, Escherichia coli PhnB and similar proteins. The Escherichia coli phnB gene is found next to an operon of fourteen genes (phnC-to-phnP) related to the cleavage of carbon-phosphorus (C-P) bonds in unactivated alkylphosphonates, supporting bacterial growth on alkylphosphonates as the sole phosphorus source. It was originally considered part of that operon. PhnB appears to play no direct catalytic role in the usage of alkylphosphonate. Although many of the proteins in this family have been annotated as 3-demethylubiquinone-9 3-methyltransferase enzymes by automatic annotation programs, the experimental evidence for this assignment is lacking. In Escherichia coli, the gene coding 3-demethylubiquinone-9 3-methyltransferase enzyme is ubiG, which belongs to the AdoMet-MTase protein family. PhnB-like proteins adopt a structural fold similar to bleomycin resistance proteins, glyoxalase I, and type I extradiol dioxygenases.	3.63031e-22
NZ_CP038517.1\|WP_017366545.1\|254390_255371_-\|glutaminase	gnl\|CDD\|237074	PRK12357, PRK12357, glutaminase; Reviewed.	0
NZ_CP038517.1\|WP_007498406.1\|247727_248165_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.55364e-20
NZ_CP038517.1\|WP_169476117.1\|255936_257175_+\|sensor-histidine-kinase	gnl\|CDD\|214643	smart00387, HATPase_c, Histidine kinase-like ATPases. Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.	4.11515e-27
NZ_CP038517.1\|WP_017366538.1\|241878_242415_+\|DUF402-domain-containing-protein	gnl\|CDD\|377233	pfam04167, DUF402, Protein of unknown function (DUF402). Family member FomD is a predicted protein from a fosfomycin biosynthesis gene cluster in Streptomyces wedmorensis. Its function is unknown.	5.94287e-16
NZ_CP038517.1\|WP_008342154.1\|252029_252890_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	8.74186e-37
NZ_CP038517.1\|WP_017366543.1\|248427_249936_+\|AMP-binding-protein	gnl\|CDD\|235730	PRK06187, PRK06187, long-chain-fatty-acid--CoA ligase; Validated.	2.19497e-142
NZ_CP038517.1\|WP_017366539.1\|242451_244083_-\|S8-family-serine-peptidase	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	5.45157e-101
NZ_CP038517.1\|WP_017366548.1\|261924_262890_-\|GHKL-domain-containing-protein	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	3.53617e-33
NZ_CP038517.1\|WP_017358609.1\|252929_254357_-\|alanine:cation-symporter-family-protein	gnl\|CDD\|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NZ_CP038517.1\|WP_017366547.1\|259451_260492_-\|DUF4352-domain-containing-protein	gnl\|CDD\|374999	pfam17118, DUF5105, Domain of unknown function (DUF5105). This is a family of Firmicutes proteins of unknown function. There is one structure, Structure 4r4g, a lipoprotein, whose N-terminus is represented by DUF4352, pfam11611.	2.9575e-62
NZ_CP038517.1\|WP_017366540.1\|244253_245738_+\|amidase	gnl\|CDD\|180608	PRK06529, PRK06529, amidase; Provisional.	5.19351e-168

>NZ_CP038517.1|WP_008342155.1|251485_251851_+|VOC-family-protein
MISVSPYIVVEDVKESLQYYQGIFGGDIRILNEHQDRVLHAELHLGESLLHFSDTFGRTPKPENLRLIMQFDNEEELKAVYEALEADGDVLVELQDTFFGALHGQVQDRKNGLIWVLNYMK
>NZ_CP038517.1|WP_017366544.1|250002_251385_+|amino-acid-permease
MRHILRKKHIHDLLEQSRQQKVKKTLGGLDLTLLGIGAVIGTGVMVLTGITAAKDAGPAVIFSFAIAAIVCSLAALCYAEMASALPVFGSAYIYSYTTMGELVGHLMGWTLLSVYMLTASAVASGWSSYFNSLLEGFGISIPHQFLAGPEQGGYMNLPAIIIALLIAWILSRGTKESKKFNNIMVFVKLGIIVLFIVVGGFYVEPANWQPFMPFGTEGIIAGAAAVFFAFLGFDAISASAEEVKNPQRNLPIGIIGSLLICTIIYIVVCLVMTGMVHYTKLNVTEAMSYVLQSVHQHSVAGIISVGAVIGLMAVIFANNYAATRIAFAMGRDGLLPKVFSKTNKSGTPVSSIWVIGGMTAVISGFIDLKDLSNLANIGALLTFAMVSLSVLILRKTHKQLERGFRVPFVPVLPIISMGCCVFLMLNLPGRTWLYFGVWLMIGVVMYAAYSNKHSELAKSA
>NZ_CP038517.1|WP_017366543.1|248427_249936_+|AMP-binding-protein
MNTLQALLNDRMERSSQIEAVTGGGVSYTFEEYAKRIDQLAHYLHRKGIRKGDRVCFICQNHHHFSTIMLAAIKAGAVAVPLSWQLTSFELEGILKKAEPKALFFDREFRDIIAAVNVSLEDCLMVESGVNAKTTQLFEDILASNDGSDLAEEVSEEDLAMILFTSGTTGNPKGCMVGHGRIYQFLTRHGNRGFDLRGKRYLASHPLYHMSSINHLIAAAIEGYTLVFLHDATPKRILETIEKERITFMMAFPSAYTYMLEEMKRGSYDLSSFEIAISGGTKVPVRLIKDYKEVGIQMMHGYGSTEAWVVSAWHPAMGEDKMGSAGKVDPDVEVKIVHPETEEALPAGEIGEVVMRSPFYFLGYYHQPEATEKVLKDGWFHMGDAGYLDEDGFLYITGRYKDVILYGGDNIYPDQVEEVIDQIPGVIESAVIGVPDDLYGEVPSAYIVKDESVDFCEEDVLNYCKERLADYKVPSIHFTQDLPKNKLGKIMKKDLRELVVNA
>NZ_CP038517.1|WP_007498406.1|247727_248165_-|MarR-family-transcriptional-regulator
MQHFELEASLLDHALTKYLKATKRIDEENIPKNVTNVKGFILRIIYRHQSCTVKNILQEVSLSPSATTTALNHLEDEGLIIRSRNNNDRRTVWITLSESGEQIARQMIDNRQLLVNQLFNHLSEEDKKTFFELIEKMMDERTLKA
>NZ_CP038517.1|WP_017366542.1|246427_247450_+|quercetin-2,3-dioxygenase
MSEQPQSIKQSEGTSFYTVSGSGELYGLENQLVHVLAEANQTNQLFELVLITGGKGAYFPLHCHETLFETIFVLEGKLEVILDGKKYMVTACDYIHIPPKTIHGYRMHSHKTRCISYTLGGQMTDVYQQIGKRLLQNEWPMTDHPFDADSFHQAEKESDIILMHGIRELSNTTKPAVLFHSQLPRAVQPYVLEAGEGKQYMVEGQLHELIATTETTGDGFSYFVIEGTKGKGLRSHYHEMHTEALYCVEGRINLQLNGENICLMPGDFAYIPPNTVHSYEFVSHSNKMLVLLLPGYIEQVFEQFEEAQSPGMCPYFIQEGNMMEGGETSTQYDLVFVEDK
>NZ_CP038517.1|WP_017366541.1|245783_246347_+|TetR/AcrR-family-transcriptional-regulator
MSTKDKIIQTAALLLRKQGYHATGLNQIIRESGTPKGSLYYYFPNGKEELAIAAVEYISQRVIDQIEASFAYSDDPYVAVDHFMTNIIRGFMEQESERGIPIVLLAAESKPEHTKLHAACKQEMIRWQELVKEKLMNSGYDETKADERASLLHSMVIGGLSMTTALKQTTPLEHVKCYLRHLFMREE
>NZ_CP038517.1|WP_017366540.1|244253_245738_+|amidase
MNVKEYMTYDATGLASLVQKKQVTPEELVQAAFARLEEVNPLLNAVIQTRRDQVFKDMKSLDADQPFAGVPFVLKNISQGLEHEPLTAGALLLKDVKAQTDSHFVRRLKQAGLLMIGHTNTPEFGLRNVTEPSLYGPTRNPWNADYSPGGSSGGTAAAVASGIVPAGGASDGGGSIRIPASFTGLFGLKPTRGRTPVGPGAGRQWQGASIDFTLTKTVRDSAALLDLLQVIQPEAAFQTPLYDGSYQEDLVKRTSSMRIAYSVDSPVGTKVSEEARQAVLNTVKWLSEQGHQIEEAKPNIDGVHLMQQYYVMNSGEMSALFTSLARSFGRPVKPEETDIVAWVLAEAGKNVTAAAYTESLDAWDMAAAKMAAFHQTYDLYVTPATAYSAPKVGELMHNDQEISALLRVSSLSMQAQQDLIYEMFLKSLTYTPFTQLANLTGQPSMSVPVHLTEAGMPLGVQVTAPKGKEDWLLRLASEIESSSLWKGTHPLLNQ
>NZ_CP038517.1|WP_017366539.1|242451_244083_-|S8-family-serine-peptidase
MQGAIALKKKIVVVIAFLLALTTALPFHSQAAAPPKETDVIIVYKNQKGKQTAIQESEKVNAQYIHLPAVAVTADEQAVTSLKKDPNIAYVSKNVRVKLAAATVKKTAAATGQDALVQKSYNLQKLNVKQAIKEGVTGKNVKVAVLDTGIFPHEDLKVAGGKSFVDYTSSYKDDEGHGTHVAGTIGALNNDYGTVGVASGVKLYAVKVLDKKGEGDLYSLLRGIDWAISNKMDIINLSLAFEDNIPILRSAVDEAYKKGLLVVAASGNDGKKNGISYPAAYNSVIAVSATTDKDKLASISNTGKGIEFSAPGENVISTYLKNEYWYATGTSQAAPHVTGMLALLKQLHPKKTNVQLRTLLRSYTVDLGAKGKDPQFGYGRVQYVPQSTFLKAATSAVKTAETSKKQTDVDQAKTKIGRLTASKQKTALTDRVKKVQTAIDIRDARAKVKSAEKNKTQGSIKSAQTAIKKLSKGKEKTSLQNRLDKVKKQVAYQKKVTDAKQKVKKAEAKRTKKTKATAQSAVKQLKASKTKTDLQKRINRIKV
>NZ_CP038517.1|WP_017366538.1|241878_242415_+|DUF402-domain-containing-protein
MFPLYANSWDDVIERKIKYDDQVVEHTCQLLDAQEQQVVLFHKIQEPFTMVAGDGTVTIPKGSYTTAYYWTDRPYNVYFWRDDQGNELGSYLNIVRHTRFEERAVVFKDLLIDLLVLPNGDFFVLDEDELPESLASFEHGSVQRALHDVIHSLAHILDQVRLDAKGKYPHTLFQKMLK
>NZ_CP038517.1|WP_008342164.1|241557_241764_-|hypothetical-protein
MNGITIIETVAELGQIILVFCGYALYWRLVKTKRDRKLTPYEHVLKFFVMFGLISWCFSYMALNVWVS
>NZ_CP038517.1|WP_008342154.1|252029_252890_+|alpha/beta-hydrolase
MDQVEFQYIQTNGIKLHTAMAGPEDGPLLVLLHGFPEFWYGWKNQIRPLAEAGYRVVVPDQRGYHLSDKPEGVESYVLDKLRDDIVGLIKALSPNQKAIVGGHDWGGAVAWHLASTRSQYVEKLIIVNMPHPRVMMKVLPFYPPQWKKSSYIAFFQLPNVPEAALQENHFQRLDEAIGLSARPHLFTKEDVSSYKLAWTQPGAITSMLNWYRGIKKGGFEKPISKRILVPVRMIWGMEDKFLSRKLAKETIKICPNGQLIFVDDATHWINHEKPDVVNKLILEFLT
>NZ_CP038517.1|WP_017358609.1|252929_254357_-|alanine:cation-symporter-family-protein
MNEKALLSYLTTTNDFIWTYLIIALLLGVGVYFTYRSRFLQVRMLKEMLRVLKEGRKEKEGISPFQAFAISMAARVGTGNITGIAIAIAIGGPGAIFWMWIVAIIGSASSFVESTLAQVYKVKDKTGFRGGPAYYMEKGLNKRWMGILFAILITISFGIVFNAVQSNTITVAFKNSFGLDRLTVGIVMAVIFAFIIFKGIKAIAKASEYIVVFLAVAYIGIAFFVIITNITELPGVISTIVKHAFGFEQFAGGTLGGALLQGIKRGLFSNEAGMGSAPNAAATAVTSHPVKQGLIQAFGVLTDTLIICTSTAFLVLFSDAYKTTNLEGIELTQASLSQHIGPWASGFLAIMIFLFAFSTLIGNYYYGETNIEFLGANKIWLNIYRVAVIGMVLFGAVATVPLVWGLADLFMGLMVIVNLIAITMLSKVAFAALKDYMRQKKEGKDPVFYKNAVPNNEEIECWDDEPVSLKKNQIG
>NZ_CP038517.1|WP_017366545.1|254390_255371_-|glutaminase
MKTAISNNTQHACQSSVDQWAEEIRPYYKNGQNAGYIPALGKVNSSQLGISVIGPDGSSVRYGDWDVPFTLQSISKVISFIAACLGRGVAYVLDRVDVEPTGDAFNSIYRLEMHKPGKPFNPMINAGAITVSSILPGKTSTEKLAYIFDLIENLIGKRPSVNEEVYQSEWATAHRNRALAYYLKETNYLESDVEDTLEVYLKQCSIEVTTEDIALIGLIISSDGYHPFKQVQVIPKDIARLTKALMLTCGMYNASGNFAAFVGVPAKSGVSGGIMACVPPSARREFPFQTGCGIGIYGPAIDDCGNSITGVMMLKKLAKEWDLSIF
>NZ_CP038517.1|WP_169476117.1|255936_257175_+|sensor-histidine-kinase
MIVIVPLAGELKFYPVNETFRISFGAPAFFFCLLLLRKSRPLLPGFLTGAAIVLFRVGLDLIQQKADLALSFYQQFPSFFFYFTYAFLFFVVRTGRFKQRSIFIGLIGLMIELLADFVELFVQFLVFDTTMTFSKLSDMILIAFAHSFVVISFFNMMRLYEAQSREKQIMKQNEHMMMVISNLYEETVHLKKTLNHTEHITQESYRLYRLLNEHEAGKKVSQELLKLAGEIHEVKKDNQRIYAGLSKLISKENMQDYMRAEDLVQIVIRIQEKYALSLGKNISFTSDIKGIHLHEYHVFIFLSLINNLMANAVEAIKDDGAISLVLKGSHDKIEIRVEDDGPGIPEKLREIVFDPGYTSKFDAYGTPSTGIGLSYVRELVQELDGQIQIEQKETKGTAFQLVLPIKNLIQRG
>NZ_CP038517.1|WP_008342149.1|257179_258118_+|DNA-binding-domain-containing-protein
MRFFIADDDRAIRSILGQIIEDEDLGEVVDEADDGVGLEAHSLNLKKVDILLIDLLMPARDGIQTIRHIHPEFKGKVIMISQVEAKEMMAEAYELGIEYYIHKPVNRIEIVSVIRKVMERIKLEKSIYDIQASLRHVLPLEPVISHETGTGSKRRTMKEAGEFLLSELGIVGESGSKDLLEILIYLHETQTANSHEVNFPPLKQLFIKTAERKLGRGASDVEVMREVKAAEQRIRRAIHHSLNHFASLGLTDFSNPKFEHYASKFFDFTDVSQRMKEMQKTSSSAGSTGRVNTKKFVQIFYFEAKQLFEGMS
>NZ_CP038517.1|WP_017366546.1|258311_259403_+|SEC-C-domain-containing-protein
MGKIKRNALCPCGSGKKYKHCCGQKSGGEQTSELVFKEAVQVQKDLMNYAFSKHQRAINQFINEFSFLADMDKETQQISVFHLSVWGIFFRPLTDKKETIFQEFLTKKAEDITRPKTRQVVESWTDMEPSLLLLNEKTDESLYFENMVTAEKVEVDVKPDQTVLPEKGSLVLGFPVQFEEKAEFFIQYTMFAKEFTDTLLLQVRQLVEAHEANGGARSTFMREAFPEVLKCMFAKQEVEETEAPAQTEGNTVGLSADRMEWASDVQLETAKLIEDGMKEHGDQSLTDGALTVWKAYCDQKAPVIRKAASFAAGIEYYIHSLASDAPLSQAQVAKKYGISASTVSSRFKDIEKAVKEEQETTVS
>NZ_CP038517.1|WP_017366547.1|259451_260492_-|DUF4352-domain-containing-protein
MNLKKISALLMISFVMIISAACQSSAKSTKADQKSTKTAEVKVNSYEYTLPEDSTTTLRDNELVLKVNLTITNKGDKALSLYNSDFTLYQDDAKVSDLKFYGSKDRLDLGSLNKGKSLSGALYFLVDKGKKYQFVYQDSIKKNSDSIEIELDGEKILDTAKKLDNPAKALSAYTDIIVFDKKNDQFSELTGDNQSDVVNKYHEMFVKDFKRSAGIYGNEVSDRDILSMYKRMQNTMKDKAKVETSVKTISDDEAKVVAQVTGIDASNLKDKLDKQRDEFYNGKIRSKEELYKKSLNMYASEFEKLPPVSSPAEYEVKMKRNGDGQWKIDLNDYNTEQYMSGFIKTR
>NZ_CP038517.1|WP_008342143.1|260958_261888_+|aldo/keto-reductase
MKKVTLGRTDLQVNPIGLGTNAVGGHNLFPNLSEDAGRELVETALDHGVNFLDSAFIYGLGRSEELIGEIIAKRGGRKELVLATKGAHKEVNGQIELDNSRDFLRQQVEDSLKRLQTDYIDLYYMHFPDGRTPLDEVAGTLKELKDEGKIRAIGASNLDFEQLQTFNRDGYLDVLQSEYSLLKRQAEQDLLPYCVEHGISFIPYFPLASGLLTGKFTKDATFDDIRAKDPLFQGDAFLQNLEKVDKLKAIAQSKHAETAHVALAWLLAQDGIDAIIPGAKRAEQVLQNLKTNDVQLTKEEINEIDQIFS
>NZ_CP038517.1|WP_017366548.1|261924_262890_-|GHKL-domain-containing-protein
MNAFYLGFRIYTLIWLGLAVHAAAKAVLPLSSSMVWLLTFCIMCLYTFFIYKRFWLGMSGYVILGAFVLITCSGISLFLNHGNGLSHLLTVIIILTADLLSFKIMQTEQRLNGRLQELIHAESRTNDLLLELRSKHHETARHLNAFSASNDEHEIKDLIQQYVKHFPWIKGENAYLASTLHSFFQRAEKEDIALSLDLQAPFSSLPFSKADQVSFTGNLLDNALDAAIEAKQAGNEGSISITTSIRSGLFLIHCENSTKGMEKHVLDHLFKTFGRSTKGGDHQGMGTYIIHQLVEKADGTLDFTYRSPNLRLVIKIPLTMA
>NZ_CP038517.1|WP_017366549.1|262901_263603_-|response-regulator-transcription-factor
MIKVGLVDDYRVDLEKLHAIVGRMDTVDIVFVTQSAEDAYEKVKQGDIDLLFADIEMPGMSGYELADLIHSHALNVDVVFVTGNSGYAVHAFDLNVHDYIMKPYQADRIAKSLERYMSTKQEKSIHGRLLIKQQSDIHVLQKKDVIFVERTGRSTTIVTTTGDIQTYQTLNELKGDLAEKDFIRSHRSFIINIHYIKNFSAYAKNSFIVSFEGTDKKAMMTKQQLEYFKKYYF

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Crispr_ID: NZ_CP038517_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP038517_2

2432230-2432312

Orphan

Consensus_repeat	Method
TTCATTTCATTTAGCGAGTAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP038517_2

>merge|NZ_CP038517|2|2432230-2432312|CRISPRCasFinder
TTCATTTCATTTAGCGAGTAATTATAGCATGTTCTCGCTTTCAGTTTTGATTGTTTTTCCTTCATTTCATTTAGTGAGTAATT

>NZ_CP038517|2|2|2432230-2432312|CRISPRCasFinder
TTCATTTCATTTAGCGAGTAATT	ATAGCATGTTCTCGCTTTCAGTTTTGATTGTTTTTCC
TTCATTTCATTTAGTGAGTAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP038517.1\|WP_017367732.1\|2430979_2432128_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_CP038517.1\|WP_008342850.1\|2444808_2446362_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|234864
NZ_CP038517.1\|WP_008342828.1\|2426453_2427389_-\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NZ_CP038517.1\|WP_008342824.1\|2424697_2425669_-\|porphobilinogen-synthase	unknown	unknown	gnl\|CDD\|236450
NZ_CP038517.1\|WP_017367731.1\|2430583_2430979_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226728
NZ_CP038517.1\|WP_017358146.1\|2438973_2440248_-\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NZ_CP038517.1\|WP_017367734.1\|2440488_2441496_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NZ_CP038517.1\|WP_008342843.1\|2441619_2442219_-\|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl\|CDD\|179314
NZ_CP038517.1\|WP_007501575.1\|2442234_2443650_-\|3-isopropylmalate-dehydratase-large-subunit	unknown	unknown	gnl\|CDD\|235490
NZ_CP038517.1\|WP_008342832.1\|2428264_2429632_-\|glutamyl-tRNA-reductase	unknown	unknown	gnl\|CDD\|234592
NZ_CP038517.1\|WP_008342834.1\|2429872_2430358_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP038517.1\|WP_007501577.1\|2443692_2444790_-\|3-isopropylmalate-dehydrogenase	unknown	unknown	gnl\|CDD\|234832
NZ_CP038517.1\|WP_008342826.1\|2425665_2426457_-\|uroporphyrinogen-III-synthase	unknown	unknown	gnl\|CDD\|119440
NZ_CP038517.1\|WP_007501566.1\|2435656_2437318_-\|ATP-dependent-protease-LonB	unknown	unknown	gnl\|CDD\|131948
NZ_CP038517.1\|WP_007501564.1\|2433160_2435485_-\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NZ_CP038517.1\|WP_017358145.1\|2437456_2438722_-\|ATP-dependent-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_CP038517.1\|WP_008342830.1\|2427426_2428257_-\|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl\|CDD\|307628
NZ_CP038517.1\|WP_007501554.1\|2423377_2424670_-\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|234607
NZ_CP038517.1\|WP_007501562.1\|2432576_2433164_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NZ_CP038517.1\|WP_007501553.1\|2421801_2423046_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|274346

Protein	Function_ID	Function_description	E-value
NZ_CP038517.1\|WP_017367732.1\|2430979_2432128_-\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0.000272841
NZ_CP038517.1\|WP_008342850.1\|2444808_2446362_-\|2-isopropylmalate-synthase	gnl\|CDD\|234864	PRK00915, PRK00915, 2-isopropylmalate synthase; Validated.	0
NZ_CP038517.1\|WP_008342828.1\|2426453_2427389_-\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	1.4064e-174
NZ_CP038517.1\|WP_008342824.1\|2424697_2425669_-\|porphobilinogen-synthase	gnl\|CDD\|236450	PRK09283, PRK09283, porphobilinogen synthase.	0
NZ_CP038517.1\|WP_017367731.1\|2430583_2430979_-\|hypothetical-protein	gnl\|CDD\|226728	COG4278, COG4278, Uncharacterized conserved protein [Function unknown].	6.60497e-06
NZ_CP038517.1\|WP_017358146.1\|2438973_2440248_-\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	1.10739e-162
NZ_CP038517.1\|WP_017367734.1\|2440488_2441496_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.39778e-07
NZ_CP038517.1\|WP_008342843.1\|2441619_2442219_-\|3-isopropylmalate-dehydratase-small-subunit	gnl\|CDD\|179314	PRK01641, leuD, 3-isopropylmalate dehydratase small subunit.	2.36409e-127
NZ_CP038517.1\|WP_007501575.1\|2442234_2443650_-\|3-isopropylmalate-dehydratase-large-subunit	gnl\|CDD\|235490	PRK05478, PRK05478, 3-isopropylmalate dehydratase large subunit.	0
NZ_CP038517.1\|WP_008342832.1\|2428264_2429632_-\|glutamyl-tRNA-reductase	gnl\|CDD\|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NZ_CP038517.1\|WP_007501577.1\|2443692_2444790_-\|3-isopropylmalate-dehydrogenase	gnl\|CDD\|234832	PRK00772, PRK00772, 3-isopropylmalate dehydrogenase; Provisional.	0
NZ_CP038517.1\|WP_008342826.1\|2425665_2426457_-\|uroporphyrinogen-III-synthase	gnl\|CDD\|119440	cd06578, HemD, Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in the human uroporphyrinogen-III synthase gene cause congenital erythropoietic porphyria, a recessive inborn error of metabolism also known as Gunther disease.	9.38398e-60
NZ_CP038517.1\|WP_007501566.1\|2435656_2437318_-\|ATP-dependent-protease-LonB	gnl\|CDD\|131948	TIGR02902, Lon_protease_2, ATP-dependent protease LonB. Members of this protein are LonB, a paralog of the ATP-dependent protease La (LonA, TIGR00763). LonB proteins are found strictly, and almost universally, in endospore-forming bacteria. This protease was shown, in Bacillus subtilis, to be expressed specifically in the forespore, during sporulation, under control of sigma(F). The lonB gene, despite location immediately upstream of lonA, was shown to be monocistronic. LonB appears able to act on sigma(H) for post-translation control, but lonB mutation did not produce an obvious sporulation defect under the conditions tested. Note that additional paralogs of LonA and LonB occur in the Clostridium lineage and this model selects only one per species as the protein that corresponds to LonB in B. subtilis. [Protein fate, Degradation of proteins, peptides, and glycopeptides, Cellular processes, Sporulation and germination].	0
NZ_CP038517.1\|WP_007501564.1\|2433160_2435485_-\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NZ_CP038517.1\|WP_017358145.1\|2437456_2438722_-\|ATP-dependent-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_CP038517.1\|WP_008342830.1\|2427426_2428257_-\|cytochrome-c-biogenesis-protein-CcsA	gnl\|CDD\|307628	pfam01578, Cytochrom_C_asm, Cytochrome C assembly protein. This family consists of various proteins involved in cytochrome c assembly from mitochondria and bacteria; CycK from Rhizobium, CcmC from E. coli and Paracoccus denitrificans and orf240 from wheat mitochondria. The members of this family are probably integral membrane proteins with six predicted transmembrane helices. It has been proposed that members of this family comprise a membrane component of an ABC (ATP binding cassette) transporter complex. It is also proposed that this transporter is necessary for transport of some component needed for cytochrome c assembly. One member CycK contains a putative heme-binding motif, orf240 also contains a putative heme-binding motif and is a proposed ABC transporter with c-type heme as its proposed substrate. However it seems unlikely that all members of this family transport heme nor c-type apocytochromes because CcmC in the putative CcmABC transporter transports neither. CcmF forms a working module with CcmH and CcmI, CcmFHI, and itself is unlikely to bind haem directly.	5.25393e-30
NZ_CP038517.1\|WP_007501554.1\|2423377_2424670_-\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|234607	PRK00062, PRK00062, glutamate-1-semialdehyde 2,1-aminomutase.	0
NZ_CP038517.1\|WP_007501562.1\|2432576_2433164_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	3.08793e-111
NZ_CP038517.1\|WP_007501553.1\|2421801_2423046_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|274346	TIGR02907, Stage_VI_sporulation_protein_D, stage VI sporulation protein D. SpoVID, the stage VI sporulation protein D, is restricted to endospore-forming members of the bacteria, all of which are found among the Firmicutes. It is widely distributed but not quite universal in this group. Between well-conserved N-terminal and C-terminal domains is a poorly conserved, low-complexity region of variable length, rich enough in glutamic acid to cause spurious BLAST search results unless a filter is used. The seed alignment for this model was trimmed, in effect, by choosing member sequences in which these regions are relatively short. SpoVID is involved in spore coat assembly by the mother cell compartment late in the process of sporulation. [Cellular processes, Sporulation and germination].	3.99878e-42

>NZ_CP038517.1|WP_017367732.1|2430979_2432128_-|MFS-transporter
MNISRVSTLVYLDTMIVFIGALVWTGLPLYFFEMTGSYFYAGSMYLIGGFSFILSNIVSNYLFKVFSRYTAKFFVTTLSILTLASFFALNNQLFNLMFFLMLAFQFFINGLSFILESGFNMFLSNQPHKDIAYRNMFLLSAKTIGFFSGPILFIFFGSEMYLVFLLFFIGLLVYEYLYPIVAQLKIESISFANVEIFKKVPKSYLCIMFIDGMFLPVVMNYSFIILKETFSASDLTVSLFWLIGGVSVLLGNLLIRRMDIQKIHSKVYLITIYLMFGLILMILAPNSSLFLIGFFILTLINPLFMSLIKASFLVVFDPHYRSMALAGMNTLNQLGTILIITVITFMLEGSEFFNISYIIPLCLCIGIIRFLILKNILKRGIQ
>NZ_CP038517.1|WP_017367731.1|2430583_2430979_-|hypothetical-protein
MDKVSYPDFSVDLVEACLKFGYYFEGMDKENVTRLVDQYKKFWFMIKKYPDCSFAPNTEIDEVWHLHMLLPQNYYYDCMSYFGVILAHDAGFGNQADEVDILNEMFDSGNDLWEKEFGFRLPDENELETKP
>NZ_CP038517.1|WP_008342834.1|2429872_2430358_+|hypothetical-protein
MKKKSILLPLTLLAVALYAILSGDQFDIWKDQEKWYTLVLLFGLAFLYQGKKEQETSHVFIGMLMTGLALHFILQPKLEHWPDTFTMIVFIIGLALLMKSSQKKEYQIESVVLIALGLFLYFFQQITKQLSTLSIPTSGFELYWPYVLIAVSLLLLFLKRK
>NZ_CP038517.1|WP_008342832.1|2428264_2429632_-|glutamyl-tRNA-reductase
MHILVVGLDYKTAPVEIREQLSFEPSELGTAMSKLKEEKSILENIVISTCNRTEIYAVVDQLHTGRFYIKRFLADWFGLEKEDVSPYLKFYENDGAVEHLFRVACGLDSMVIGETQILGQVRSSFKVAQEEKTIGTVFNYLFKQAVTVAKRSHAETDIASNAVSVSYAAVELAKKIFGRLSDKHVLILGAGKMGELAAQNLQGQGIGQVTVINRTFEKAKELAGRFSGEPKSLNQLEKTLSEADILISSTGAKQFVITKEMVEKANKQRKGRPLFMVDIAVPRDLDPAISEVEGAFLYDIDDLEGIVAANLKERRAVAEEVELLIEAEIVEFKQWLNTLGVVPVISALREKALSIQADTMQSIERKLPNLTNREMKLLNKHTKSIINQMLKDPILKAKEIAGEPNAEEKLLLFKEIFDLQVEDEEQKAEPMQVEQGAFQLFKSNMAQGLATVASE
>NZ_CP038517.1|WP_008342830.1|2427426_2428257_-|cytochrome-c-biogenesis-protein-CcsA
MMESIVARLGEATILIYALSVLFYFIDFLQHNRKAGKMAFWLLSIVWLLQTVYMFYIMMETDRFPVLNVAEGLYFYTWVLVTLSLVLTKVLRVEFIVFFTNVIGFSMMAIHTFTPSDLHSAELTGKLTSELLVIHITMAILSYGAFSLSFAFSLLYLFQYRLLKKKKWGKWLLRIEDLSKLDHMAYVLNIIGVPMLLLSLILGIIWAYISYDTLYWTDAKVLGSFIMLFLYGFYLYIRLVRNMQGKIVARWNVASFLVLMINYFLLGSLSTFHWFQ
>NZ_CP038517.1|WP_008342828.1|2426453_2427389_-|hydroxymethylbilane-synthase
MRTIKVGSRRSKLAITQTKWVIQKLSELNPSYSFEIKEIVTKGDQILDVTLSKVGGKGLFVKEIEQAMLNHDIDMAVHSMKDMPASLPEGLVIGCIPEREDVRDALISKDHLRLHELPKGAIVGTSSLRRSAQLLQERPDLEIKWIRGNIDTRLEKLKNEEYDAIILAAAGLSRMGWSQEVVSEFLSPDTCLPAVGQGALSIECRGDDEELLQLLAQFTNEYTKKTVLAERAFLKQMDGSCQVPIAGYATMNERDEIELTGLVASADGHTIIRETVTGTDPEAIGTACAKHMADKGAKDLIDKVKKDLSSQ
>NZ_CP038517.1|WP_008342826.1|2425665_2426457_-|uroporphyrinogen-III-synthase
MTIAKSLYGQTVLVTRNERQAGAFQQKIEALNGHAVLTSLIRFEPTLTKEKAKAFLEDLEASHWLVFTSVNGASFFLSYIEKHQLHQSLSHLKVAAVGEKTSAYLMQHGLKVDVVPERFIAEELADALIEHVHPEECVFVAKGHLSRDVVKNTLVPLGIDVKEWIIYETVKDEDGIIALKSAMMEQSFDFITFTSSSTVHSFMHAMEADIDRLAASDTCFVSIGPLTQEALLQYGISSETPDTYTIDGMLDLMCRLSERKLNQ
>NZ_CP038517.1|WP_008342824.1|2424697_2425669_-|porphobilinogen-synthase
MMKFNRHRRLRTSAGMRELVRETFLRPSDFIYPIFFVEGENVRKEVPSMPGVYHISVDLVKEEVQELVDLGIKSIIVFGVPDHKDHVGSEAYHDHGIVQRATLEIKKHFPELVAIADTCLCQYTDHGHCGIVEDGEILNDESLQLLAKTAVSQARAGADIIAPSNMMDGFVIAIREALDEAGFVHVPVMSYAVKYASAFYGPFRDAAHSTPQFGDRKTYQMDPANRLEALREAQSDVEEGADFLIVKPSLSYLDIMRDVKNEFTLPVVAYNVSGEYAMVKAAAQNGWISEKELVLEMLTSMKRAGAELIITYHAKDAAKWLSE
>NZ_CP038517.1|WP_007501554.1|2423377_2424670_-|glutamate-1-semialdehyde-2,1-aminomutase
MGRSYEKSKQAFKEAQQLMPGGVNSPVRAFKSVNTDPIFMERGKGAKIYDIDGNEYIDYVLSWGPLILGHTNDRVVESIQRVAEHGTSFGASTLVENELAKLVSERVPSIEVIRMVSSGTEATMSALRLARGFTGRNKIVKFEGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGTASNTITVPYNDLESIKVAFEEFGDDIAGVIVEPVAGNMGVVPPQEGFLQGLRDITEQYGSLLIFDEVMTGFRVDYHCAQGYFGITPDLTCLGKVIGGGLPVGAYGGRADIMRQIAPSGPIYQAGTLSGNPLAMTAGLETLKQLTPESYEEFRRKGDRLEEGISKAAKAHGIPLTFNRAGSMIGFFFTNEQVVNYDTAKTADLALFAEFYKEMADHGIFLPPSQFEGLFLSTTHTDEDIEYTIETVEKVFQKLAQ
>NZ_CP038517.1|WP_007501553.1|2421801_2423046_-|LysM-peptidoglycan-binding-domain-containing-protein
MSQNNRLQFSVEESIYFKNGQEVSELLSISLDPDILVQEVNDYVSIRGSLELTGEYNINQEELMGESSSYASYRQADEVKVREDGTAELLHQFPVDITIPKNKISHLNDVFVFIDAFDYQLTESRLLTIQADLAIEGLLDEGTPEPLVEEPYEFVHRAEEEYGDVTYEYQAQSEYEEQEMLPREEHEENAEQQAVLQHEARTEQEEDEIDIETVMVEEAEEEEEYEEEEAVALGYRSFPEAQVQEPPFFDPPKLLEEEERDDTFFEVEVRKDPEAESKEEEEPPAYPAFESPAYQMEQTQEERDDSYQFERLYEREAPKVYESAQEAEEFEHDQREASGSENSLYLTKLFAKQEEEDFSRMKICIVQQEDTVDRICERYQLNVQQLLRTNSLSVDAELEEGQILYIPEYQKSNA
>NZ_CP038517.1|WP_007501562.1|2432576_2433164_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MKVTKSDIVISAVKPEQYPSGGLPEIALAGRSNVGKSSFINSLINRKNLARTSSKPGKTQTLNFYIINDMLHFVDVPGYGFAKVSKTEREAWGRMIETYITMREELKAVVQIVDLRHKPSADDVNMYEFLKYYGVPVIIIATKADKIPKGKWEKHAKVVKQTLDIDPSDELILFSSETKKGKDEAWNAILAKINS
>NZ_CP038517.1|WP_007501564.1|2433160_2435485_-|endopeptidase-La
MADEIKKNVPLLPLRGLLVYPTMVLHLDVGREKSVQALEQAMMNDHMIFLATQREISIDEPGEEEIFKVGTYTKIKQMLKLPNGTIRVLVEGLNRAQIESYMELEDYTSVDIKELTEEELKDAEAEALMRTLLDHFDQYIKISKKISAETYATVTDIEEPGRMADIVASHLPLKLKDKQEVLETVDVKKRLNRVISLIHNEKEVLEIEKKIGQRVKRSMERTQKEYYLREQMKAIQKELGDKEGKTGEVSTLMAKIEESGMPDSVRETALKELNRYEKIPSSSAESSVIRNYIDWLINLPWGTYTEDRLDLKLASEILDDEHHGLEKVKERVLEYLAVQKLTNSLKGPILCLAGPPGVGKTSLAKSIAKSLDRKFIRISLGGVRDESEIRGHRRTYVGAMPGRIIRGMSKAGTMNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPEQNHNFSDHYIEETFDLSQVLFIATANNLATIPGPLRDRMEIITIAGYTEVEKAEIVKDHLLPKQLKEHGLKKGNLQLREAAIYDMIRYYTREAGVRGLERQLAAICRKAARAIVAEDRKRITVTEKNLSEFLGKRLYRYGQAETTDQVGVVTGLAYTTVGGDTLSIEVSLSPGKGKLLLTGKLGDVMRESAQAAFSYIRSKADELNIDPQFNEKHDIHIHVPEGAVPKDGPSAGITIATALVSALTGRPVSKEVGMTGEITLRGRVLPIGGLKEKALGAHRAGLKTIILPKDNEKDIDDIPESVREGLTFIPVSHLDEVLEKALVGEGR
>NZ_CP038517.1|WP_007501566.1|2435656_2437318_-|ATP-dependent-protease-LonB
MSWTGIVLFIQLFFGIVIGLYFWNLLKNQRTQKVTIDKESKKEMEALRKMRSIKLSEPLSERVRPKGFQDIVGQEDGIRALKAALCGPNPQHVIVYGPPGVGKTAAARLVMEEAKRHADSPFKKDAVFVELDATTARFDERGIADPLIGSVHDPIYQGAGAMGQAGIPQPKQGAVTHAHGGVLFIDEIGELHPIQMNKMLKVLEDRKVFLDSAYYSEENTQIPNHIHDIFQNGLPADFRLIGATTRTPDEIPPAIRSRCLEIFFKDLDQHELKIVAAKAVEKIQKELSDEGLNLLTSYVKNGREAVNMVQIAAGMAVTENRKDITIADVEWVIHSSQLTPRYEQKVPEKPKVGVVNGLAVYGPNSGALLEIEVNICKALEKGSINITGIAEEESIGNQSKSIRRKSMAKGSVENVLTVLRNLGIRTNEYDIHINFPAGAPIDGPSAGIAMATAIFSAIHQIPIDHLTAMTGEIGLQGQVKPIGGVIPKIKAAKQAGVKTVIIPYDNQQSILKEIEGVTIVPVKHFQEVLDQCLVNPPDEKKDGLEEEMKRKSV
>NZ_CP038517.1|WP_017358145.1|2437456_2438722_-|ATP-dependent-protease-ATP-binding-subunit-ClpX
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPHEIREILDEYVIGQENAKKSLAVAVYNHYKRINSNSKIDDVELSKSNISMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGAENKIEDLEKEVLLSKVLPEDLLRFGLIPEFIGRLPVIASLEPLDEKALVEILTKPKNALVKQYTKMLELDDVELEFEEDALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGETVADGEPPRLVLKDGTVVNKDTKTSA
>NZ_CP038517.1|WP_017358146.1|2438973_2440248_-|trigger-factor
MSVKWEKQEGNEGVLTVEVDAETFNKALDDAFKKVVKQVSIPGFRKGKVPRGLFEQRFGVESLYQDALDILLPVEYPKAIDEAGIEPVDRPEIDVEKIEKGESLIFTAKVTVKPEVKLGDYKGLNVEKDDTSVSDEDVQEELKAMQNRQAELVVKEEGAIENGDTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEEQLVGLEAGAEKDVEVTFPEEYHAEDLAGKPAVFKVKIHEIKAKELPALDDEFAKDVDEEVETIAELTEKTKKRLEEAKENEAEGKLREELVAKASENAEVDVPQAMVDTELDRMMKEFEQRLQMQGMNLELYFQFSGQDEDALKEQMKEDAAKRVKSNLTLEAIAAAEDLQVSDEEVEEELSKMAEAYNMPVENIKQAIGSTEAMKEDLKVRKAIDFLVENR
>NZ_CP038517.1|WP_017367734.1|2440488_2441496_-|tetratricopeptide-repeat-protein
MKHDKKKDNVILFPGLKERLIEKGMAALKDKQYQEALHLFSEAKSYDDDEESDIHLGMAICFLELGELQDAKRVCEKMLHEGYGHYFTVLQVYMTILIQLKEYEEVKQTIEAVLEENHLPAESAEHFYKLLEFSRKMIESPEEILDEDEEGSGEINIDEMLERPEEQVQFIHSLKDRNITPHMGLLNTILQKPDGNPLVKSLILQLLSDHDVAKPVHVTKFGDSLTLVPSEAVKPEQMPLLQQVLRKLDDTLGNENPTLYQGVEELWRRHLFVLYPFLPKYTDPNLWAAALHKVGYEMHGIEIDLEELHLLYDFKERELREACTMLKDIEEISYL
>NZ_CP038517.1|WP_008342843.1|2441619_2442219_-|3-isopropylmalate-dehydratase-small-subunit
MEPLVTHKGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFDWRYLADGSPNPDFELNQPIYEGASILIAGENFGCGSSREHAPWALDDYGFKIVIAPSFADIFHQNCFKNGMLPIRLDYDVWKTFAASYENKGYEMTVDLEKQQIQDHEGNVTPFDVDPHWREMLLNGYDEISLTLLLEDEIQAFEEKRSSWLRA
>NZ_CP038517.1|WP_007501575.1|2442234_2443650_-|3-isopropylmalate-dehydratase-large-subunit
MPRTIIEKIWDQHVVKNGEGKPDLLYIDLHLVHEVTSPQAFEGLRQKGRKVRRPQNTFATMDHNIPTVNRFVIKDEIAKKQVSALERNCAEFGVRLADLHSVDQGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRPKTLEIRVDGTLQKGVTAKDVILAVIGAHGVKFGSGYVIEYTGEVFRNMSMDERMTVCNMSIEAGARAGLIAPDEVTFEYCRGRKYAPQGEDFEAAIKEWKELRTDPGATYDKTIVLDGNHISPMVTWGINPGMVLPVDAAIPGPEDFAQEDDQKEAKRAYEYMGVHPHQRIEDITIEHVFIGSCTNSRMTDLRQAASMIEGQKVADHVRAIVVPGSQSVKLQAEEEGLHEIFLEAGFEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGRFVDVRKFNQEKTVV
>NZ_CP038517.1|WP_007501577.1|2443692_2444790_-|3-isopropylmalate-dehydrogenase
MKKKIALLPGDGIGPEVVTSAVAVLKETAAQFQHEFEFETALIGGIAIDEKNNPLPKETVEVCKSADAILLGAVGGPKWDQNPPELRPEKGLLSIRKQLDLFANIRPVKVFDSLSEASPLKQDHISGVDFVIVRELTGGLYFGEPSERYTDDEGKEAAVDTLLYTKEEIVRVLKEAFDMALTRRKKVTSVDKANVLASSKLWRDAVEEVASQYPDVAYEHMLVDNAAMQLIYKPAQFDVIVTENMFGDILSDEASMITGSLGMLPSASLSSTGLHLYEPIHGSAPDIAGQNVANPLATILSAASLLRTSFALEEEAAAIEAAVEAVLASGKRTKDLASKEGTYETTDDITKAVVDALKQRAKTIV
>NZ_CP038517.1|WP_008342850.1|2444808_2446362_-|2-isopropylmalate-synthase
MRKINFFDTTLRDGEQSPGVNLNAQEKLIIAKQLERLGVNIIEAGFPASSRGDFLGVQEIARTIKNCSVAGLARCVKGDIDAAWDALKDGAQPRIHVFIATSDIHLKHKLKKTREEVVEQAVSMVKYAKERFPVVQWSAEDACRTDLSFLAEIVEKVIDAGASVINLPDTVGYLAPKEYGNIFKYMKEHVPNIDQVILSAHCHDDLGMAVANSLAAIENGADQIETAVNGIGERAGNAALEEIAVALHIRKDFYQVESTIQLNEIKRTSDVVSKYSGMIVPRNKAVVGNNAFAHESGIHQDGFLKEKTTYEIISPELVGVTTDVLVLGKHSGRHAFKDRLKTLGFKLTEEEINKFFETFKNLTEKKKEITDDDLISIILEEKVADRKIGYEFESLQVHYGTEQMPTATVSLKNQETQEVIQEAATGAGSVEAVYNTLERCMEERIHLLDYRIQSNGKGRDALAEVYVTVSIEGKETAGRGVAQDVLEASAKAYVNAVNRHLIFKSNLIEIEKHHAIS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

620303 : 630199

Synechococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017366748.1\|620303_621599_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	2.9e-18	26.9
WP_017366749.1\|621671_622394_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3G7P8	Synechococcus_phage	1.8e-46	43.7
WP_003214349.1\|622386_622641_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FKD5	Synechococcus_phage	1.2e-05	33.3
WP_017359821.1\|622637_623321_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_008344291.1\|623304_625536_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.9e-159	42.0
WP_017359819.1\|625511_626942_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.3e-51	32.9
WP_017366751.1\|627038_628079_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.1e-65	43.8
WP_008344288.1\|628075_628645_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.9e-31	39.5
WP_008344287.1\|628660_630199_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	4.8e-76	51.8

DBSCAN-SWA_2

1645244 : 1651493

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017359034.1\|1645244_1645637_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	G3MBF1	Bacillus_virus	8.8e-27	56.5
WP_017359033.1\|1645596_1647699_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	U5PY35	Bacillus_phage	0.0e+00	82.8
WP_008344010.1\|1647716_1648697_+	class 1b ribonucleoside-diphosphate reductase subunit beta	F8WQ21	Bacillus_phage	4.2e-150	80.6
WP_017367289.1\|1648781_1649399_+	hypothetical protein	A0A127AYS1	Bacillus_phage	1.9e-44	44.3
WP_008344009.1\|1649454_1650213_-	N-acetylmuramoyl-L-alanine amidase	A0A0N6W8I1	Bacillus_phage	8.7e-47	53.8
WP_008344008.1\|1650533_1651493_+	stage V sporulation protein K	G3MAX6	Bacillus_virus	3.9e-52	39.6

DBSCAN-SWA_3

2009894 : 2017602

Ostreococcus_lucimarinus_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017367507.1\|2009894_2010986_-	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	2.4e-21	27.6
WP_008344548.1\|2010985_2012158_-	chorismate synthase	A0A291AU41	Pandoravirus	7.6e-42	35.2
WP_008344547.1\|2012234_2013011_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_003216015.1\|2013155_2013602_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.5e-27	42.3
WP_007500951.1\|2013731_2014694_-	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	1.7e-07	26.0
WP_007500957.1\|2014718_2015423_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_008344543.1\|2015426_2016194_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_008344541.1\|2016309_2016540_-	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_003215789.1\|2016563_2017133_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	1.8e-49	57.3
WP_003215863.1\|2017323_2017602_-	non-specific DNA-binding protein Hbs	A7KV42	Bacillus_phage	5.6e-28	74.2

DBSCAN-SWA_4

2055466 : 2062047

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017367523.1\|2055466_2056618_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.9e-24	37.7
WP_017367524.1\|2056728_2057208_-	YpuI family protein	NA	NA	NA	NA
WP_008344462.1\|2057321_2057915_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.0e-15	36.0
WP_007501021.1\|2057904_2058663_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	6.5e-10	36.8
WP_008359694.1\|2058873_2058966_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_017367525.1\|2059054_2059579_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_008344455.1\|2059803_2060157_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_007501031.1\|2060270_2060735_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.1e-43	66.0
WP_017367526.1\|2060761_2061385_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.6e-57	58.6
WP_026050106.1\|2061396_2062047_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.7e-41	40.8

DBSCAN-SWA_5

2385445 : 2438722

Moraxella_phage(22.22%)

protease,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_017367711.1\|2385445_2386591_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.2e-85	43.5
WP_017367712.1\|2386622_2387651_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_008342752.1\|2387685_2387886_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_017367713.1\|2387878_2388883_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.1e-07	31.0
WP_017358123.1\|2388894_2389500_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_008342756.1\|2389647_2390160_-	BofC C-terminal domain-containing protein	NA	NA	NA	NA
WP_017367714.1\|2390386_2391031_+	serine/threonine protein kinase	V5L5V0	Insectomime_virus	7.0e-05	27.6
WP_008342761.1\|2391063_2391246_-	hypothetical protein	NA	NA	NA	NA
WP_017367715.1\|2391438_2391588_+	hypothetical protein	NA	NA	NA	NA
WP_026050120.1\|2391619_2393380_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_008342767.1\|2393854_2394487_+	LysE family transporter	NA	NA	NA	NA
WP_017367717.1\|2394533_2395154_-	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_017367718.1\|2395287_2396478_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_017367719.1\|2396609_2397719_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_017367720.1\|2397705_2398569_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_017367721.1\|2398550_2400122_-	L-aspartate oxidase	NA	NA	NA	NA
WP_171814638.1\|2400220_2401363_+	IscS subfamily cysteine desulfurase	A0A1X7QGF3	Faustovirus	4.4e-26	28.6
WP_017367723.1\|2401365_2401905_+	transcription repressor NadR	NA	NA	NA	NA
WP_017367724.1\|2401928_2402807_-	prephenate dehydratase	NA	NA	NA	NA
WP_008342790.1\|2402825_2403269_-	ACT domain-containing protein	NA	NA	NA	NA
WP_007501521.1\|2403324_2404611_-	GTPase ObgE	NA	NA	NA	NA
WP_007501522.1\|2404632_2405226_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_003216586.1\|2405503_2405788_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_017367725.1\|2405800_2406139_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003216781.1\|2406153_2406462_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_017367726.1\|2406614_2407484_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_008342800.1\|2407476_2408268_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_017358134.1\|2408377_2409181_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_007501533.1\|2409183_2409867_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_017358135.1\|2409921_2410440_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_007501536.1\|2410436_2411336_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_007501538.1\|2411363_2412383_-	rod shape-determining protein	NA	NA	NA	NA
WP_026050121.1\|2412473_2413148_-	DNA repair protein RadC	NA	NA	NA	NA
WP_017358136.1\|2413196_2413766_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_017358137.1\|2413943_2415137_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_017358138.1\|2415117_2415849_-	prepilin peptidase	NA	NA	NA	NA
WP_034646530.1\|2415998_2417303_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_017367728.1\|2417368_2420011_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.4e-160	42.1
WP_026050122.1\|2420466_2420658_+	hypothetical protein	NA	NA	NA	NA
WP_017367730.1\|2420732_2421764_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_007501553.1\|2421801_2423046_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_007501554.1\|2423377_2424670_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_008342824.1\|2424697_2425669_-	porphobilinogen synthase	NA	NA	NA	NA
WP_008342826.1\|2425665_2426457_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_008342828.1\|2426453_2427389_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_008342830.1\|2427426_2428257_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_008342832.1\|2428264_2429632_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_008342834.1\|2429872_2430358_+	hypothetical protein	NA	NA	NA	NA
WP_017367731.1\|2430583_2430979_-	hypothetical protein	A0A2I2L429	Orpheovirus	2.6e-10	37.9
WP_017367732.1\|2430979_2432128_-	MFS transporter	NA	NA	NA	NA
WP_017367733.1\|2432198_2432339_-	hypothetical protein	NA	NA	NA	NA
WP_007501562.1\|2432576_2433164_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_007501564.1\|2433160_2435485_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	8.3e-181	43.7
WP_007501566.1\|2435656_2437318_-\|protease	ATP-dependent protease LonB	A0A0R6PGP8	Moraxella_phage	1.9e-17	26.9
WP_017358145.1\|2437456_2438722_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.3e-148	64.2

DBSCAN-SWA_6

2467181 : 2511660

Bacillus_phage(70.59%)

tail,protease,head,integrase,plate,portal,terminase,capsid,transposase,holin

attL 2466133:2466149|attR 2517015:2517031

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2466133:2466149	attL	NA	NA	NA	NA
WP_017367746.1\|2467181_2468735_+\|transposase	transposase	NA	NA	NA	NA
WP_017367747.1\|2468751_2469090_+	hypothetical protein	NA	NA	NA	NA
WP_008345914.1\|2469620_2470145_-	metallophosphoesterase	NA	NA	NA	NA
WP_089374139.1\|2470159_2470762_-	XTP/dITP diphosphatase	Q66YC8	Euphorbia_ringspot_virus	8.8e-10	31.2
WP_007501599.1\|2470772_2471501_-	ribonuclease PH	NA	NA	NA	NA
WP_017367749.1\|2471652_2472714_-	GerMN domain-containing protein	NA	NA	NA	NA
WP_100218322.1\|2472815_2473634_-	glutamate racemase	NA	NA	NA	NA
WP_007501606.1\|2473641_2474082_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_042631274.1\|2474231_2474306_-	hypothetical protein	NA	NA	NA	NA
WP_017367751.1\|2474352_2475876_-	recombinase family protein	A0A290FZV2	Caldibacillus_phage	3.2e-141	51.3
WP_017367752.1\|2476007_2476550_+	hypothetical protein	NA	NA	NA	NA
WP_017367753.1\|2476632_2476824_+	hypothetical protein	A0A2H4J4T3	uncultured_Caudovirales_phage	1.1e-22	82.3
WP_017367755.1\|2476996_2477470_-	hypothetical protein	NA	NA	NA	NA
WP_017367756.1\|2477629_2478430_-	N-acetylmuramoyl-L-alanine amidase	Q9ZXD7	Bacillus_phage	2.8e-64	55.8
WP_017367757.1\|2478477_2478897_-\|holin	phage holin family protein	D6R405	Bacillus_phage	1.4e-46	75.0
WP_017367758.1\|2478941_2479121_-	XkdX family protein	NA	NA	NA	NA
WP_017367759.1\|2479117_2479411_-	hypothetical protein	NA	NA	NA	NA
WP_017367760.1\|2479426_2480770_-\|plate	BppU family phage baseplate upper protein	M4ZRP1	Bacillus_phage	2.0e-41	43.9
WP_026050125.1\|2480759_2481023_-	hypothetical protein	NA	NA	NA	NA
WP_100218324.1\|2481034_2482870_-	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_017367763.1\|2482977_2484714_-\|tail	phage tail protein	D6R400	Bacillus_phage	3.0e-183	55.9
WP_017367764.1\|2484734_2485568_-\|tail	phage tail family protein	D6R3Z9	Bacillus_phage	9.1e-106	68.2
WP_017367765.1\|2485567_2489584_-\|tail	phage tail tape measure protein	D6R3Z8	Bacillus_phage	0.0e+00	68.9
WP_017367766.1\|2489599_2489794_-	hypothetical protein	D6R3Z7	Bacillus_phage	5.5e-14	73.2
WP_017367767.1\|2489796_2490132_-	hypothetical protein	Q9ZXE8	Bacillus_phage	1.6e-29	59.8
WP_017367768.1\|2490170_2490797_-\|tail	major tail protein	Q9ZXE9	Bacillus_phage	2.1e-54	52.4
WP_017367769.1\|2490808_2491177_-	DUF3168 domain-containing protein	Q9ZXF0	Bacillus_phage	2.9e-32	54.1
WP_017367770.1\|2491173_2491557_-	HK97 gp10 family phage protein	Q9ZXF1	Bacillus_phage	8.8e-48	72.4
WP_017367771.1\|2491549_2491915_-\|head	phage head closure protein	Q9ZXF2	Bacillus_phage	3.1e-26	49.6
WP_017367772.1\|2491868_2492192_-\|head,tail	phage gp6-like head-tail connector protein	Q9ZXF3	Bacillus_phage	5.7e-24	56.1
WP_017367773.1\|2492206_2492608_-	collagen-like protein	D6R3Z0	Bacillus_phage	2.2e-09	44.0
WP_017367774.1\|2492632_2492929_-	hypothetical protein	Q9ZXF5	Bacillus_phage	1.0e-27	71.1
WP_017367775.1\|2492949_2494137_-\|capsid	phage major capsid protein	Q9ZXF6	Bacillus_phage	1.3e-145	66.7
WP_017367776.1\|2494172_2494805_-\|head,protease	HK97 family phage prohead protease	Q9ZXF7	Bacillus_phage	2.7e-94	82.7
WP_017367777.1\|2494797_2496039_-\|portal	phage portal protein	D6R3Y6	Bacillus_phage	1.3e-201	81.0
WP_017367779.1\|2496244_2497957_-\|terminase	terminase large subunit	D6R3Y4	Bacillus_phage	2.1e-282	82.4
WP_017367780.1\|2497956_2498463_-\|terminase	phage terminase small subunit P27 family	Q9ZXG2	Bacillus_phage	8.9e-80	89.3
WP_017367781.1\|2498549_2498873_-	hypothetical protein	Q9T203	Bacillus_phage	1.9e-19	41.6
WP_017367782.1\|2498862_2499222_-	HNH endonuclease	Q38456	Bacillus_phage	8.6e-53	76.9
WP_017367783.1\|2499322_2499850_-	hypothetical protein	NA	NA	NA	NA
WP_017367784.1\|2499850_2501191_-	AAA family ATPase	Q2P9X8	Enterobacteria_phage	1.0e-05	35.6
WP_017367785.1\|2501403_2501982_-	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_017367786.1\|2502231_2503185_-	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_017367787.1\|2503266_2503809_-\|integrase	site-specific integrase	D2XR58	Bacillus_phage	3.4e-53	58.4
WP_017367788.1\|2503805_2504255_-	DUF1492 domain-containing protein	S6AVV9	Thermus_phage	6.3e-37	53.7
WP_017367789.1\|2504482_2505088_-	hypothetical protein	NA	NA	NA	NA
WP_017367790.1\|2505122_2505530_-	hypothetical protein	A0A2H4J8A0	uncultured_Caudovirales_phage	3.1e-14	42.6
WP_017367791.1\|2505526_2505736_-	hypothetical protein	NA	NA	NA	NA
WP_017367792.1\|2505738_2506032_-	hypothetical protein	NA	NA	NA	NA
WP_017367793.1\|2506028_2506205_-	hypothetical protein	NA	NA	NA	NA
WP_017367794.1\|2506215_2506956_-	hypothetical protein	A0A2H4J6H9	uncultured_Caudovirales_phage	1.7e-127	96.3
WP_017367795.1\|2506984_2508244_-	DNA cytosine methyltransferase	A0A1I9KFD6	Aeromonas_phage	4.3e-115	44.1
WP_017367796.1\|2508240_2508489_-	hypothetical protein	A0A2H4JA61	uncultured_Caudovirales_phage	8.0e-26	74.1
WP_017367797.1\|2508521_2508731_-	hypothetical protein	NA	NA	NA	NA
WP_017367798.1\|2508801_2508975_-	hypothetical protein	NA	NA	NA	NA
WP_017367799.1\|2508988_2509129_-	BH0509 family protein	NA	NA	NA	NA
WP_017367801.1\|2509237_2509768_-	hypothetical protein	NA	NA	NA	NA
WP_017367802.1\|2509764_2509920_-	hypothetical protein	NA	NA	NA	NA
WP_034646534.1\|2510003_2510825_-	ATP-binding protein	A0A0U3U1U1	Bacillus_phage	7.0e-50	39.7
WP_017367804.1\|2510808_2511660_-	phage replisome organizer N-terminal domain-containing protein	V5UQV4	Oenococcus_phage	1.9e-50	41.7
2517015:2517031	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2722036 : 2788175

Clostridium_phage(23.33%)

tail,plate,portal,terminase,capsid,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008342944.1\|2722036_2722441_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_008342942.1\|2722598_2722790_-	hypothetical protein	NA	NA	NA	NA
WP_007501934.1\|2722914_2723352_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	4.8e-50	65.5
WP_017358370.1\|2723483_2723630_+	YtzI protein	NA	NA	NA	NA
WP_017367907.1\|2723638_2724076_-	FixH family protein	NA	NA	NA	NA
WP_008342935.1\|2724199_2724673_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_008342933.1\|2724801_2725026_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.1e-25	70.3
WP_017367908.1\|2725027_2725594_-	carbonic anhydrase	NA	NA	NA	NA
WP_017367909.1\|2725807_2726800_+	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_017367910.1\|2726877_2727120_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_017367911.1\|2727295_2728627_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_169476099.1\|2728649_2729696_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_008360682.1\|2729764_2729923_+	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_017358376.1\|2729948_2730140_+	hypothetical protein	NA	NA	NA	NA
WP_017358377.1\|2730245_2731370_-	o-succinylbenzoate synthase	NA	NA	NA	NA
WP_026050135.1\|2731356_2732817_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.8e-80	35.5
WP_008342913.1\|2732887_2733706_-	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_017358379.1\|2733720_2734551_-	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_017367912.1\|2734535_2736278_-	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_017367913.1\|2736270_2737689_-	isochorismate synthase MenF	NA	NA	NA	NA
WP_017358382.1\|2738071_2739010_+	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_017367914.1\|2739127_2739862_+	TraR/DksA C4-type zinc finger protein	NA	NA	NA	NA
WP_008342900.1\|2739949_2740426_+	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_007500615.1\|2748411_2748987_+	energy-coupled thiamine transporter ThiT	NA	NA	NA	NA
WP_017367915.1\|2749226_2749781_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_017367916.1\|2749950_2750589_+	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_017367917.1\|2750603_2751758_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_026050136.1\|2751754_2752897_+	putative lipid II flippase FtsW	NA	NA	NA	NA
WP_008344044.1\|2752928_2754476_-	flotillin family protein	A0A2I2L4B2	Orpheovirus	9.5e-08	28.4
WP_017367919.1\|2754487_2755018_-	hypothetical protein	NA	NA	NA	NA
WP_019743389.1\|2755223_2755703_+	DinB family protein	NA	NA	NA	NA
WP_008344050.1\|2755743_2756952_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_008344052.1\|2756979_2758449_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_008344054.1\|2758655_2759213_+	GbsR/MarR family transcriptional regulator	NA	NA	NA	NA
WP_017367920.1\|2759417_2759864_-	hypothetical protein	NA	NA	NA	NA
WP_017367921.1\|2759967_2760786_-	N-acetylmuramoyl-L-alanine amidase	Q9ZXD7	Bacillus_phage	4.2e-63	69.9
WP_008361671.1\|2760805_2761069_-\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	5.9e-27	69.0
WP_017367922.1\|2761081_2761294_-	hypothetical protein	A0A290GDY2	Caldibacillus_phage	5.1e-13	53.6
WP_017367923.1\|2761330_2761471_-	XkdX family protein	NA	NA	NA	NA
WP_017367924.1\|2761470_2761791_-	hypothetical protein	O64053	Bacillus_phage	1.8e-17	44.2
WP_034646641.1\|2761803_2763186_-	hypothetical protein	A0A1P8CWR7	Bacillus_phage	2.8e-27	30.4
WP_017367926.1\|2763641_2764847_-	hypothetical protein	A0A2H4J4R1	uncultured_Caudovirales_phage	1.7e-65	51.5
WP_017367927.1\|2765056_2765233_-\|portal	phage portal protein	NA	NA	NA	NA
WP_017367928.1\|2765229_2765559_-\|portal	phage portal protein	A0A2H4JCI0	uncultured_Caudovirales_phage	3.7e-10	36.2
WP_017367929.1\|2765569_2766442_-	hypothetical protein	NA	NA	NA	NA
WP_017359000.1\|2766457_2766841_-\|tail	phage tail protein	NA	NA	NA	NA
WP_017367930.1\|2766852_2767776_-	YmfQ family protein	A0A0A7RTT8	Clostridium_phage	1.2e-10	28.5
WP_017367931.1\|2767762_2768809_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.9e-68	43.2
WP_017367932.1\|2768801_2769224_-	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_017358996.1\|2769238_2769505_-	DUF2577 family protein	S6C459	Thermus_phage	4.7e-08	37.5
WP_017367933.1\|2769501_2770512_-	hypothetical protein	H7BV96	unidentified_phage	1.0e-34	28.4
WP_007500584.1\|2770523_2771192_-	LysM peptidoglycan-binding domain-containing protein	A0A0K2SUI2	Clostridium_phage	2.9e-22	29.6
WP_017367934.1\|2771184_2775177_-	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	7.3e-44	45.3
WP_008344097.1\|2775232_2775370_-	hypothetical protein	NA	NA	NA	NA
WP_008344099.1\|2775411_2775852_-\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	1.7e-10	35.8
WP_074041930.1\|2776002_2776092_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003213309.1\|2776368_2776812_-\|tail	phage tail tube protein	A0A0A7RVP1	Clostridium_phage	7.6e-27	46.5
WP_017367936.1\|2776813_2778160_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A7S087	Clostridium_phage	4.3e-81	41.4
WP_008344108.1\|2778163_2778376_-	hypothetical protein	NA	NA	NA	NA
WP_017367937.1\|2778362_2778818_-	hypothetical protein	NA	NA	NA	NA
WP_017358988.1\|2778822_2779320_-	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	7.0e-37	46.2
WP_017367938.1\|2779316_2779673_-	YqbH/XkdH family protein	NA	NA	NA	NA
WP_007500574.1\|2779669_2780053_-	DUF3199 family protein	NA	NA	NA	NA
WP_008344119.1\|2780066_2780990_-\|capsid	phage major capsid protein	A0A1B1P7E3	Bacillus_phage	3.3e-109	64.3
WP_017358985.1\|2781012_2782104_-	hypothetical protein	A0A1B1P7E4	Bacillus_phage	5.2e-61	40.9
WP_017358984.1\|2782145_2783597_-\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	1.9e-138	53.0
WP_100218326.1\|2783593_2784895_-\|terminase	PBSX family phage terminase large subunit	M4ZRM5	Bacillus_phage	1.1e-153	62.8
WP_008344125.1\|2784903_2785551_-	helix-turn-helix domain-containing protein	A0A2P1JTW4	Anoxybacillus_phage	2.5e-42	43.7
WP_007500562.1\|2785702_2786221_-	sigma-70 family RNA polymerase sigma factor	A0A2H4J6J3	uncultured_Caudovirales_phage	1.4e-35	47.5
WP_008344129.1\|2786345_2786552_-	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	9.0e-15	68.5
WP_008344131.1\|2786548_2786953_-	hypothetical protein	NA	NA	NA	NA
WP_017358978.1\|2787055_2787238_-	hypothetical protein	NA	NA	NA	NA
WP_017358977.1\|2787227_2787380_-	hypothetical protein	A0A2H4J4L6	uncultured_Caudovirales_phage	8.7e-07	59.5
WP_017358976.1\|2787398_2787638_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_007500560.1\|2787797_2788175_+	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	1.6e-17	45.4

DBSCAN-SWA_8

3101632 : 3110348

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_100218313.1\|3101632_3102983_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.8e-111	73.2
WP_017368107.1\|3103043_3103787_-	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_008348124.1\|3103825_3104083_-	HPr family phosphocarrier protein	NA	NA	NA	NA
WP_008348125.1\|3104109_3105060_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	4.3e-51	38.1
WP_017368108.1\|3105077_3106037_-	YvcK family protein	A1IMD5	Streptococcus_phage	3.2e-62	40.7
WP_025208027.1\|3106037_3106925_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	4.3e-05	26.3
WP_008348133.1\|3106964_3107429_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_024719880.1\|3107786_3108737_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	4.8e-87	53.1
WP_017357905.1\|3108971_3110348_-	C40 family peptidase	A0A0A0RVE6	Bacillus_phage	1.1e-26	54.3

DBSCAN-SWA_9

3743369 : 3752083

uncultured_Mediterranean_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173962628.1\|3743369_3744644_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.2e-95	50.1
WP_007496062.1\|3744745_3745573_+	chemotaxis sensory transducer	A0A2H4J162	uncultured_Caudovirales_phage	9.3e-10	55.2
WP_017366699.1\|3745882_3746542_-	deoxynucleoside kinase	C1KFI3	Lactobacillus_virus	8.4e-22	33.2
WP_017366700.1\|3746538_3747162_-	deoxynucleoside kinase	A0A1G5SAJ8	Enterococcus_phage	2.0e-12	28.8
WP_017366701.1\|3747241_3748543_-	glycoside hydrolase family 18 protein	A0A2P1CIG4	Microbacterium_phage	1.4e-07	34.8
WP_008342017.1\|3748588_3749143_-	cysteine hydrolase	NA	NA	NA	NA
WP_008342015.1\|3749222_3749699_+	nucleoside deaminase	NA	NA	NA	NA
WP_008342013.1\|3750370_3752083_+	DNA polymerase III subunit gamma/tau	D9ZNI9	Clostridium_phage	6.8e-55	34.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP038517

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection