CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP046108	Enterococcus faecalis strain 133170041-3 chromosome, complete genome	3 crisprs	csa3,cas3,DEDDh,DinG,cas14j,csn2,cas2,cas1,cas9	17	6
NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	1 crisprs	NA	4	0
NZ_CP046110	Enterococcus faecalis strain 133170041-3 plasmid pTEF2, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046108_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046108_1

1030698-1030811

Orphan

Consensus_repeat	Method
GAACAGTACAAGGTGACCAAAGGGAACGTTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP046108_1

>merge|NZ_CP046108|1|1030698-1030811|CRISPRCasFinder
GAACAGTACAAGGTGACCAAAGGGAACGTTGTCTCCTCTATGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAGATGTGGAACAGCACAAGGTGACCAAAGGGAACGTTGT

>NZ_CP046108|1|1|1030698-1030811|CRISPRCasFinder
GAACAGTACAAGGTGACCAAAGGGAACGTTGT	CTCCTCTATGTTAAAACAAACTGCTTAGCCAAAAACATGGAGTAGATGTG
GAACAGCACAAGGTGACCAAAGGGAACGTTGT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046108.1\|WP_002382760.1\|1022133_1022991_-\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NZ_CP046108.1\|WP_002370425.1\|1032027_1034112_+\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_CP046108.1\|WP_002359745.1\|1028608_1029511_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_CP046108.1\|WP_002379669.1\|1031117_1032026_+\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473
NZ_CP046108.1\|WP_002372180.1\|1038165_1039047_+\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NZ_CP046108.1\|WP_002356753.1\|1034151_1034343_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_CP046108.1\|WP_002382764.1\|1028193_1028595_+\|diacylglycerol-kinase-family-protein	unknown	unknown	gnl\|CDD\|260134
NZ_CP046108.1\|WP_002356743.1\|1024481_1025504_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NZ_CP046108.1\|WP_002356755.1\|1034376_1035309_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|235040
NZ_CP046108.1\|WP_002356759.1\|1037274_1038060_+\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NZ_CP046108.1\|WP_002356741.1\|1023897_1024347_+\|GatB/YqeY-domain-containing-protein	unknown	unknown	gnl\|CDD\|370480
NZ_CP046108.1\|WP_002356761.1\|1039307_1040030_+\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NZ_CP046108.1\|WP_002356748.1\|1029593_1030382_+\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|273175
NZ_CP046108.1\|WP_002356756.1\|1035475_1035751_-\|acylphosphatase	unknown	unknown	gnl\|CDD\|224174
NZ_CP046108.1\|WP_002370426.1\|1027730_1028210_+\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NZ_CP046108.1\|WP_002394710.1\|1023089_1023530_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NZ_CP046108.1\|WP_002367049.1\|1036653_1037091_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236715
NZ_CP046108.1\|WP_002356740.1\|1023695_1023872_+\|30S-ribosomal-protein-S21	unknown	unknown	gnl\|CDD\|234707
NZ_CP046108.1\|WP_002356757.1\|1035857_1036634_+\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223640
NZ_CP046108.1\|WP_002356744.1\|1025532_1027731_+\|HDIG-domain-containing-protein	unknown	unknown	gnl\|CDD\|224397

Protein	Function_ID	Function_description	E-value
NZ_CP046108.1\|WP_002382760.1\|1022133_1022991_-\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	4.76001e-139
NZ_CP046108.1\|WP_002370425.1\|1032027_1034112_+\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_CP046108.1\|WP_002359745.1\|1028608_1029511_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	0
NZ_CP046108.1\|WP_002379669.1\|1031117_1032026_+\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0
NZ_CP046108.1\|WP_002372180.1\|1038165_1039047_+\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	3.81848e-146
NZ_CP046108.1\|WP_002356753.1\|1034151_1034343_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	6.66934e-06
NZ_CP046108.1\|WP_002382764.1\|1028193_1028595_+\|diacylglycerol-kinase-family-protein	gnl\|CDD\|260134	cd14265, UDPK_IM_like, Integral membrane undecaprenol kinase and similar enzymes. This mostly bacterial family of homo-trimeric integral membrane enzymes, the products of the dgkA gene, catalyzes the ATP-dependent phosphorylation of undecaprenol to undecaprenyl phosphate. C55-isoprenyl (undecaprenyl) pyroposphate acts as a scaffold for the assembly of peptidoglycan components; undecaprenol kinase (UDPK) is involved in recycling undecaprenyl units for re-use in the peptidoglycan biosynthesis. UDPK does not participate in the de-novo biosynthesis of undecaprenyl phosphate. Gram-positive bacteria have a large pool of free undecaprenol, in contrast to gram-negative bacteria. UDPK may also play a role in a stress-induced pathway that affects the function of ribosomes. In Streptococcus mutans, UDPK has been shown to be required for biofilm formation, such as in the case of smooth surface dental caries. Members of the UDPK family have low activity as diacylglycerol kinases (DAGK), and many of them are annotated as DAGKs.	5.07031e-42
NZ_CP046108.1\|WP_002356743.1\|1024481_1025504_+\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	3.84494e-145
NZ_CP046108.1\|WP_002356755.1\|1034376_1035309_-\|membrane-protein-insertase-YidC	gnl\|CDD\|235040	PRK02463, PRK02463, OxaA-like protein precursor; Provisional.	1.42463e-134
NZ_CP046108.1\|WP_002356759.1\|1037274_1038060_+\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	3.78425e-167
NZ_CP046108.1\|WP_002356741.1\|1023897_1024347_+\|GatB/YqeY-domain-containing-protein	gnl\|CDD\|370480	pfam09424, YqeY, Yqey-like protein. The function of this domain found in the YqeY protein is uncertain.	1.89434e-63
NZ_CP046108.1\|WP_002356761.1\|1039307_1040030_+\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	1.02758e-148
NZ_CP046108.1\|WP_002356748.1\|1029593_1030382_+\|DNA-repair-protein-RecO	gnl\|CDD\|273175	TIGR00613, DNA_repair_protein_RecO, DNA repair protein RecO. All proteins in this family for which functions are known are DNA binding proteins that are involved in the initiation of recombination or recombinational repair. [DNA metabolism, DNA replication, recombination, and repair].	6.18949e-71
NZ_CP046108.1\|WP_002356756.1\|1035475_1035751_-\|acylphosphatase	gnl\|CDD\|224174	COG1254, AcyP, Acylphosphatases [Energy production and conversion].	1.58992e-26
NZ_CP046108.1\|WP_002370426.1\|1027730_1028210_+\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	1.48805e-60
NZ_CP046108.1\|WP_002394710.1\|1023089_1023530_+\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	6.13419e-35
NZ_CP046108.1\|WP_002367049.1\|1036653_1037091_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236715	PRK10562, PRK10562, putative acetyltransferase; Provisional.	1.03251e-32
NZ_CP046108.1\|WP_002356740.1\|1023695_1023872_+\|30S-ribosomal-protein-S21	gnl\|CDD\|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	8.30263e-11
NZ_CP046108.1\|WP_002356757.1\|1035857_1036634_+\|RNA-methyltransferase	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	9.03482e-72
NZ_CP046108.1\|WP_002356744.1\|1025532_1027731_+\|HDIG-domain-containing-protein	gnl\|CDD\|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	6.87785e-159

>NZ_CP046108.1|WP_002356748.1|1029593_1030382_+|DNA-repair-protein-RecO
MALGETKGIILFTKDFKEKDKLVKIFTESYGKLMFFVKGAHRKNNPLLPAILPFTEAVYIGNFREEGLSFLNSSKEVQPFRNIQQDIFINAYGTYILNLVDAAIEDQHYDPNLFQFTHMALSALNEQKDPEIITNIFEIQLLERFGVRPEWHHCVACGETQGKFDYSSKYSGVLCEKHWHLDEQRYHADPRAIHFIRLFAQVSYEKVQNIQVKEETKKSIRETIDMLYDEYVGLHLKSKKFIDQMKTWENTLKIPPRKKEEK
>NZ_CP046108.1|WP_002359745.1|1028608_1029511_+|GTPase-Era
MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
>NZ_CP046108.1|WP_002382764.1|1028193_1028595_+|diacylglycerol-kinase-family-protein
MALKDEQTGKNKHFINSLEFAWQGIKTVFREERNMRKHVAFGVTAIVFGFLFSLTLAEWLWLLLAVFLVWLAEIINTIFENVVDMFTDFHFHPIGKKVKDMAAGAVLLTAGFAVLVGLILFVPKILQIIQMWK
>NZ_CP046108.1|WP_002370426.1|1027730_1028210_+|rRNA-maturation-RNase-YbeY
MDITFIDETEKVPTEEIKEIENLLQFAAGFLEIAEDTEMSVTFTDNAGIQVINRDYRGKDMPTDVISFALEDEGEDELPIIFDDEELAELPRNLGDLIISTERAAEQAFEYGHTLEREMGFLAVHGFLHLNGYDHMEPEDEKEMFGLQKEILDAYGLKR
>NZ_CP046108.1|WP_002356744.1|1025532_1027731_+|HDIG-domain-containing-protein
MKKVLTKLGDRLGKAYLPILLAVFSLLLFMIMFGSVHQKRVEIKEGQLAEKTIRANKNIENTYETEQRKKLAAEAVTPEYIYQEDTASVQHNRIDKLFKLIDSANEKVDKEYSNKQAKAKKEETIPAPTVEERVASLKSLFESLPQDEVTFYQSFPNVFYQTIFTLTSEQLDKVRSESLMLVDDAMQNHVRESDLDKIRQEANGKIQYLDITSTMQQVIRYIVNQGIVVNDIANEKRTEELRQKAMNAVQPAMIYQGEIIVREGTQIDAKAVEKLELLGMTSQNTSIFPMVALALAILLQVEVLIFFTKQVTEPSRQRSFIIFYTGAMLISVILMKFFQIFQTEQLMYIPLFYPAAFAPLILNHFVNRRSGIIAAIFQVVFALFIFYNSIGTNSLTVILIMYLFSGFLATVVKRKRMSEQVFPALMWVVVFPVFMAVVLMIYQGMSLTDGKTWTALICASAGTVLSFLATMGLHPYIELLVTDDSMIVLNELSNPNHPLLKQLLEEAPGTYHHSMMVASLSANAVAEIGGRSLLTRVACYYHDIGKIKHANFFVENLPAGAENPHNFLLPEDSKQIIFGHVIDGAKILEEYNMPQMVIDICRQHHGTTLMKFFYVKAKERNPEIKESDFRYPGPRPQTREAGIVSIADTCEAAVRAMDHPTNEKIQAFVHNVIQDRISDGQLDECGLTMKEIRIIEKSLINGLCSTFHSRIKYPKMKAEAEEMKDEQEKRDD
>NZ_CP046108.1|WP_002356743.1|1024481_1025504_+|PhoH-family-protein
MWYHCKGLYNKGDGRFLTDNQSKSLELILTDSDDAHMLLGTHDKHIKFLEENTHVTINSRGEVIQLIGESSEVELVASVLRALQTLIQRGIKVHTPDVVSALKMAKAGNLEAFIAMYEEEIMKDHHGRAIRIKNVGQKKYIDAVKTHDVIFGVGPAGTGKTFLAVVMAVAALKKGEVQKIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQIFGMDHTNRLMERGVIEIAPLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGFSSKMIVNGDTSQIDLPRGVTSGLVNAERTLKDIEKIAFVNFEASDVVRHPVVAQIIQAYEKEQQKHS
>NZ_CP046108.1|WP_002356741.1|1023897_1024347_+|GatB/YqeY-domain-containing-protein
MSLLTTLNDDIKTAMKAKDKETLAVLRMLKTAIQNDQIKAGRELNGEEELTVLSREMKQRKDSLSEFEKAGRDDLVEKVKVEIAIVEKYMPQQLTEEEIRQLVQEVMTQTGATSPKDFGKVMGAMMPKVKGKADGNQVNAIVKELLQEN
>NZ_CP046108.1|WP_002356740.1|1023695_1023872_+|30S-ribosomal-protein-S21
MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVKRKKKSEAARKRKKF
>NZ_CP046108.1|WP_002394710.1|1023089_1023530_+|transcriptional-repressor
MVMAPVKTNIEQALETMKASGLKYTKKRELLMSYLIKRNRYVSAREVYEFMNETFKGVSYDTVYRNLHDFERLELLEKTELNGEQKFRFRCCQEVEHHHHFICTVCGKTEEIHMCPMNFFEEQLKGCSIEGHRFEILGRCADCCEK
>NZ_CP046108.1|WP_002382760.1|1022133_1022991_-|kinase/pyrophosphorylase
MTISEEKKCVTIFVISDSAGETASKLAAASMAQYPTVDFTLIRRTFVKDEDKLVQALEDAKKAEAMVLHTIINDHLVAIANQFFNEHQLFHFDILTPPVAEIERLTGVAPMREPGALHHLNENYFKRIEAMEFAVKYDDGKDPRGFLEADVLLLGVSRTSKTPLSLFLANKNLKVANLPLIPEAHLPKQLFEMDPKKIVGLTNDPNVLNGIRKERMRAYGLPENTSYSDIEKIRRELAFANDLYQKLGCIVIDVASLSIEETASMILNALNLEDHSYYSTETSED
>NZ_CP046108.1|WP_002379669.1|1031117_1032026_+|glycine--tRNA-ligase-subunit-alpha
MKNKLTVQEMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFLRAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLKLLGIDPLEHDIRFVEDNWENPSMGCAGLGWEVWLDGMEITQFTYFQQVGGLQCHPVTSEITYGLERLASYIQEVESVYDLEWTQGVKYGEIFVQPEYEHSKYSFEISNQEMLLENFDKFEKEAKRCIEESLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNMARSVAKIFVAEREKLGFPLLNKDQSVSKEAE
>NZ_CP046108.1|WP_002370425.1|1032027_1034112_+|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGLEEMPAHVVTPSRIQLEEKVIKFLDEHHLDYETVQSFATPRRLAVKVTAIPEKQADVEEEVKGPAKKIALDAEGNWSKAAQGFVRGQGVTTEDIVFKELNGVEYVYVTKFTKGQSAKEVLTKLNDVITSLTFPVTMHWANYDFEYIRPIHWIVALLDDEVIPFKVLDVTTGQTSRGHRFLGDDVTFQHANEYEAKLKEQFVVVQPNERKQMIVDQANALAAEKNWQLALDEELLEEVTNLVEYPTAFVGSFDEKYLSVPDEVLVTSMKEHQRYFEVRNDQGLLMPHFIAVRNGDNVHLENVIKGNEKVLIARLEDAEFFYNEDKKLTIEACVEKLKNVTFHEKIGSIYEKMQRVALIAQIIGRKVGLSEEELEDLKRASEIYKFDLVTNMVGEFPELQGIMGEKYALLQGEKPAVATAIREHYLPTSSEGELPETAIGAVLALADKLDSVFSFFSVGMIPTGSNDPYALRRQTYGVIRIIEDKGWTFPLVQLQTEVDEAVNQDVEKYGVLLNEGQAEVVEFVKARLRQLLMTKNVRHDIIDAVVSAEQADLSKLFASANILKSRFEDQDFKPSMEALTRVINLAKKGQELLGDTEEGIDPSLFENKAEKELYQAVNDLSEAFATRTIAENYEALVNLRPLIDAYFNETMVMVEDEKVKQNRLKQLMQIAKMALSIASLDLLIVK
>NZ_CP046108.1|WP_002356753.1|1034151_1034343_+|hypothetical-protein
MLETTFEQILTQLSKPAVRALTNEKIDSVDELYARGRKALLSLHGFGPKSIRTIEEMTGKELK
>NZ_CP046108.1|WP_002356755.1|1034376_1035309_-|membrane-protein-insertase-YidC
MRKLNRWLYGSGLLFLVMFLSGCVKTGADGQPTGEGFVYNFLVLPMSNAITYLVDNFNWNYGWAIIFITIIVRIIILPLGLHQSKKSFIQTEKMQAIKPQVDVAQAKMKQASTREEQMAAQAELQKIYKENNVSMVGGIGCLPLLIQMPIFSSLFFAARYTKGIATASFLGMNLGQPNMILVALAGLAYLAQGYISMIGIPEEQKKTMKSMLIVSPLMIVFMSFSSPAGVALYWVVGGIFTCIQSAITNILLRPRIKKQVQEELKNNPPKQVVTPIKDVTPKETNKVTQKTNQPKANGNKGRNAGKQKRK
>NZ_CP046108.1|WP_002356756.1|1035475_1035751_-|acylphosphatase
MEKLRMNVQGRVQGVGFRYMTKMVADQLGVTGSVKNEDDGSVSITAIAPEDIMETFIKKIKDSPSPAGRVTYVDIQEDPLLEETEQFKVIQ
>NZ_CP046108.1|WP_002356757.1|1035857_1036634_+|RNA-methyltransferase
MKEITSTKNNQLKEWKKLHKKKYREELNQYIIEGFHLVEEAVKANADVQWILFNQRGQQEWGTWLAEQETEKLIFVSDEVLNSLSELPTSQGILAIVTLETQQEQSLSFKGGWLLLDNIQDPGNVGTMIRTADAAGLAGVILGKGTADIYNTKVLRSMQGSHYHLPVLQRELTEVVQAFKKQGLPVFGTELNEAAIAYYEQEAVENYALILGNEGSGVSPELLAETTKNLYIPMKGQAESLNVAIAAGVLMFYFENNQ
>NZ_CP046108.1|WP_002367049.1|1036653_1037091_+|GNAT-family-N-acetyltransferase
MLTIKKTTQLTEKELETIMAIWLQTNLEAHPFVAPTYWQENKAFVRAALPKATLILAEEEGQIIGFLGLMDNYIAGIFIKKAFQGKGIGQKLLQVAKEEQDLLSLAVYRKNQAAYAFYQKQGFVQQKRTIDETGNEECHLVWQAQ
>NZ_CP046108.1|WP_002356759.1|1037274_1038060_+|30S-ribosomal-protein-S2
MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
>NZ_CP046108.1|WP_002372180.1|1038165_1039047_+|elongation-factor-Ts
MADVTAKMVKELRDMTGVGMMDAKKALVKVEGDMEKAVDFLRENGMAKAAKKNDRIAAEGLANVATVGNVAAIVEVNSETDFVSKNEMFQDLVKDIATKVAENKPATMEEAMAIKTEKGTIESDLIEATTVIGEKISFRRFEVVEKADNAAFGAYLHMGGRIAVLTVIDGTTDEEVAKDVAMHIAAINPRYVNESQIPQEELEHEKAVLTEQALNEGKPANIVEKMVVGRLQKFKAEIALVDQPFVKDPDMTVEKFVASKGGVVKSFVRFEVGEGIEKREDNFADEVMSQMKN
>NZ_CP046108.1|WP_002356761.1|1039307_1040030_+|UMP-kinase
MVKPKYQRVVLKLSGEALAGEDGFGIKPPVIKEIVQEIKEVHELGIEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENLGVPTRVQTSIEMRQIAEPYIRRRAERHLEKGRVVIFAGGTGNPYFSTDTTAALRAAEVDADVILMAKNNVDGVYSADPRVDETATKFEELTHLDVISKGLQVMDSTASSLSMDNDIPLVVFNLNEAGNIRRAILGENIGTTVRGK

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Crispr_ID: NZ_CP046108_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046108_2

1234036-1234336

Orphan

II-A,II-B

Consensus_repeat	Method
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACT	CRISPRCasFinder
GTTTTAGAGTCATGTTGTTNAGAATGGTACCAAAAC	CRT

4 spacers

The CRISPR arrays of NZ_CP046108_2

>merge|NZ_CP046108|2|1234036-1234336|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACCACTTCCCAAATAGAAAGGACGATGAAACAGTTTTAGAGTCATGTTGTTCAGAATGGTACCAAAACCTAATGTCAAAACAGCAGCTACATTTCTCCGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTGGGTTGACTAAAGAGCCGTCAAAAGTTTTGTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACTCAAGAAATTGCATTAAGTTCAAAAAATTTGTTTTAGAGCCATGTTGTTAAAAAACAAACTATCACC

>NZ_CP046108|2|1|1234036-1234269|PILER-CR
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CACTTCCCAAATAGAAAGGACGATGAAACA
GTTTTAGAGTCATGTTGTTCAGAATGGTACCAAAAC	CTAATGTCAAAACAGCAGCTACATTTCTCC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGGGTTGACTAAAGAGCCGTCAAAAGTTTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC

>NZ_CP046108|2|2|1234036-1234336|CRISPRCasFinder
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACC	ACTTCCCAAATAGAAAGGACGATGAAACA
GTTTTAGAGTCATGTTGTTCAGAATGGTACCAAAACC	TAATGTCAAAACAGCAGCTACATTTCTCC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACT	GGGTTGACTAAAGAGCCGTCAAAAGTTTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAACT	CAAGAAATTGCATTAAGTTCAAAAAATTT
GTTTTAGAGCCATGTTGTTAAAAAACAAACTATCACC

>NZ_CP046108|2|1|1234036-1234335|CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	CACTTCCCAAATAGAAAGGACGATGAAACA
GTTTTAGAGTCATGTTGTTCAGAATGGTACCAAAAC	CTAATGTCAAAACAGCAGCTACATTTCTCC
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TGGGTTGACTAAAGAGCCGTCAAAAGTTTT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	TCAAGAAATTGCATTAAGTTCAAAAAATTT
GTTTTAGAGCCATGTTGTTAAAAAACAAACTATCAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046108.1\|WP_002356976.1\|1236156_1237170_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|376764
NZ_CP046108.1\|WP_002356965.1\|1229685_1230255_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|379115
NZ_CP046108.1\|WP_002356957.1\|1223577_1224552_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_CP046108.1\|WP_002362075.1\|1226491_1227616_+\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NZ_CP046108.1\|WP_002372053.1\|1247683_1248433_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_CP046108.1\|WP_002402469.1\|1230680_1232930_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NZ_CP046108.1\|WP_002369917.1\|1238904_1240671_+\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
NZ_CP046108.1\|WP_002356983.1\|1246864_1247566_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_CP046108.1\|WP_002360017.1\|1242786_1243998_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224172
NZ_CP046108.1\|WP_002378476.1\|1240750_1241731_-\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NZ_CP046108.1\|WP_002372057.1\|1233014_1233878_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP046108.1\|WP_002356963.1\|1229037_1229553_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	unknown	unknown	gnl\|CDD\|176643
NZ_CP046108.1\|WP_002360016.1\|1241852_1242758_+\|prenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_CP046108.1\|WP_002356959.1\|1225921_1226266_+\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP046108.1\|WP_002364367.1\|1244311_1246735_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NZ_CP046108.1\|WP_002356966.1\|1230352_1230718_+\|DUF1033-family-protein	unknown	unknown	gnl\|CDD\|336361
NZ_CP046108.1\|WP_002369918.1\|1237174_1238908_+\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|274323
NZ_CP046108.1\|WP_002356958.1\|1224708_1225854_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP046108.1\|WP_002356956.1\|1222615_1223365_-\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NZ_CP046108.1\|WP_002356974.1\|1234741_1236160_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|376587

Protein	Function_ID	Function_description	E-value
NZ_CP046108.1\|WP_002356976.1\|1236156_1237170_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|376764	pfam02322, Cyt_bd_oxida_II, Cytochrome bd terminal oxidase subunit II. This family consists of cytochrome bd type terminal oxidases that catalyze quinol-dependent, Na+-independent oxygen uptake. Members of this family are integral membrane proteins and contain a protohaem IX centre B558. One member of the family, Klebsiella pneumoniae CydB, is implicated in having an important role in micro-aerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae. The family forms an integral functional unit with subunit I, family Bac_Ubq_Cox, pfam01654.	9.60464e-103
NZ_CP046108.1\|WP_002356965.1\|1229685_1230255_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.91104e-15
NZ_CP046108.1\|WP_002356957.1\|1223577_1224552_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_CP046108.1\|WP_002362075.1\|1226491_1227616_+\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NZ_CP046108.1\|WP_002372053.1\|1247683_1248433_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.5478e-110
NZ_CP046108.1\|WP_002402469.1\|1230680_1232930_+\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NZ_CP046108.1\|WP_002369917.1\|1238904_1240671_+\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
NZ_CP046108.1\|WP_002356983.1\|1246864_1247566_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	5.36718e-38
NZ_CP046108.1\|WP_002360017.1\|1242786_1243998_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.24993e-121
NZ_CP046108.1\|WP_002378476.1\|1240750_1241731_-\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	4.36842e-80
NZ_CP046108.1\|WP_002372057.1\|1233014_1233878_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.55306e-27
NZ_CP046108.1\|WP_002356963.1\|1229037_1229553_-\|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein	gnl\|CDD\|176643	cd00865, PEBP_bact_arch, PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea. PhosphatidylEthanolamine-Binding Proteins (PEBPs) are represented in all three major phylogenetic divisions (eukaryotes, bacteria, archaea). The members in this subgroup are present in bacterial and archaea. Members here include Escherichia coli YBHB and YBCL which are thought to regulate protein phosphorylation as well as Sulfolobus solfataricus SsCEI which inhibits serine proteases alpha-chymotrypsin and elastase. Although their overall structures are similar, the members of the PEBP family have very different substrates and oligomerization states (monomer/dimer/tetramer). In a few of the bacterial members present here the dimerization interface is proposed to form the ligand binding site, unlike in other PEBP members.	5.73504e-32
NZ_CP046108.1\|WP_002360016.1\|1241852_1242758_+\|prenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	8.82053e-105
NZ_CP046108.1\|WP_002356959.1\|1225921_1226266_+\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.33245e-53
NZ_CP046108.1\|WP_002364367.1\|1244311_1246735_+\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	7.68936e-175
NZ_CP046108.1\|WP_002356966.1\|1230352_1230718_+\|DUF1033-family-protein	gnl\|CDD\|336361	pfam06279, DUF1033, Protein of unknown function (DUF1033). This family consists of several hypothetical bacterial proteins. Many of the sequences in this family are annotated as putative DNA binding proteins but the function of this family is unknown.	4.62165e-64
NZ_CP046108.1\|WP_002369918.1\|1237174_1238908_+\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|274323	TIGR02857, transport_ATP-binding_protein, thiol reductant ABC exporter, CydD subunit. The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD.	0
NZ_CP046108.1\|WP_002356958.1\|1224708_1225854_+\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	4.17386e-179
NZ_CP046108.1\|WP_002356956.1\|1222615_1223365_-\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	6.42122e-104
NZ_CP046108.1\|WP_002356974.1\|1234741_1236160_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|376587	pfam01654, Cyt_bd_oxida_I, Cytochrome bd terminal oxidase subunit I. This family are the alternative oxidases found in many bacteria which oxidize ubiquinol and reduce oxygen as part of the electron transport chain. This family is the subunit I of the oxidase E. coli has two copies of the oxidase, bo and bd', both of which are represented here In some nitrogen fixing bacteria, e.g. Klebsiella pneumoniae this oxidase is responsible for removing oxygen in microaerobic conditions, making the oxidase required for nitrogen fixation. This subunit binds a single b-haem, through ligands at His186 and Met393 (using SW:P11026 numbering). In addition His19 is a ligand for the haem b found in subunit II.	0

>NZ_CP046108.1|WP_002372057.1|1233014_1233878_+|AraC-family-transcriptional-regulator
MLANLNQAMDYIEEHLTEEVSFDELAKKTGISVYHFKRTFSFVAGMSLAEYIKKRRLAEANLALLAGEKVTDVAFKYGYQSIEGFSRAFRDWTGQAPSEVMKTQIQKTFPKFSFYIDIKGGQSMDVKLIEKPAFQIVGVSQKVPLQYQGENQAIIELAQRITPQQRAEMHTFDDVYPHQVVNASFDFQEGRTTEGGEMTHMIGFVTSQENTYEDLEQLSVPAHTWAVFPNEGPFPQTLQETWARIFSEWLPSSGYQVVAAPEISFTQYQGPAEAKYSEIWLAVTATK
>NZ_CP046108.1|WP_002402469.1|1230680_1232930_+|DNA-topoisomerase-III
MAKQNSANGKLFETHEFKEKPQGIFFKLFFYSRNLEKIEPIFGIIRKDSTQKGAKLVVAKQLIIAEKPSVAKDLSRVLGANQKNKNYYEGPNVIVTWALGHLLGLKMPEDLNKEWQTWQMETLPMIPKNLGIKPLPKTGHQLKAIKQLANRKDVSEAVIATDAGREGELVARWILEYVRFNKPVKRLWISSQTDKAIKDGFKKIRPAKDYDNLYYSALARAKADWLVGLNVTRALTVKYQDNLSAGRVQTPTLAMVRQQEKTIEQFKPQTYFTISLTVESEKAKMTQKNPYALKERQEAEQLVKELSKQKGLVTDIQEKVKTENAPLPYDLTEIQREANQRFQFSAKKTLSLVQSLYETHKIVSYPRTDSKYLTTDMKGTMKERLQAIADFSPEVKGYLKNGAVVKQQKVFQNAKVTDHHGLIPTEQRPRYEKLSNDEQKIYQMIVQRFLGLFAEPNQTKQTKVTVAFGKETFVFHQNKVVVAGWKTTAEQPLSTVQWQKGMTVAPNFTINKELTSPPKPLTEGTLLGKMEKHSLGTPATRAEIIEKLIKSELMERTNSGLSVSAKGKQLLDLVNPSLVTPELTEKWEKSLEAIASGQQKSQLFLKDIEEDTKKLVREIKQSEKKYQDFSITQKKCPDCGSNLREKNTKDGKIYVCTNQECSYRRRKDPKVSNHRCPQCHKKMVIIEGKNGRSFKCKFCSITEKIPDKKERKQKMTKHEERRLMKKYSQPDEPEESALAQALKAAMNQE
>NZ_CP046108.1|WP_002356966.1|1230352_1230718_+|DUF1033-family-protein
MYQVITMYGDNEPWWFFDDWQEDIVQEKTFDNLTDAETYYVEVWQKLSQNYTYVNTKPNYLTAFWNDGEERWCEECDEDLQQYFGLALLENHHAVTFENKAEFTTISNHFGKTKFCKRKVI
>NZ_CP046108.1|WP_002356965.1|1229685_1230255_+|TetR/AcrR-family-transcriptional-regulator
MAKKRNLTKAKILESARNLAEELGVQQLTFQNLAVDLGIKYPSLYNHFKNIAEVKNALVDLLIQELNDALRRALVGKSGAEAIRIYAETYQQFAFENSAVYELLISVPKTQNQQLIEGIHETNQIILQLLAFYPFNNEERLHKSRELRSLIHGYITLRFLGYFQREEATPEESYRRMIEDFIASLEVAG
>NZ_CP046108.1|WP_002356963.1|1229037_1229553_-|YbhB/YbcL-family-Raf-kinase-inhibitor-like-protein
MHITNRSHLADRYGKRTSAEFLLHERPILSFPISLAAIPKEARYLSWELIDYDTIPLIGFPFIHWLAANVPVTNEIPEDFSRTALKPTIQGKNSLASPLGKQMIPALATETLPELTERYLGLSPRSGVHTYTLYVYATKNPLNLKEGFFANELHQALNDQLLAKAKFEFLY
>NZ_CP046108.1|WP_002362075.1|1226491_1227616_+|tRNA-2-thiouridine(34)-synthase-MnmA
MADNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVAKVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRLGRTPNPDVMCNKEIKFKAFLDYAMQLGADYVATGHYAQVETDENGVVHMLRGIDNNKDQTYFLSQLSQAQLAKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGVCFIGEKNFKEFLSNYLPAKKGNMVTEDGEIKGQHDGLMYYTIGQRQGLGIGGGGKTQEPWFVIGKDLTTNTLYVGQGFHHEKLYATHLEASEVHFTVDTPMPKEFDCTAKFRYRQADIPVHVSLSEDGTKATVTFKEPARAVTPGQAVVFYDGMECLGGGLIDRAYQDEKELQYV
>NZ_CP046108.1|WP_002356959.1|1225921_1226266_+|DUF1831-domain-containing-protein
MAFTTTAAVEGSTVFYKVHPSAKRYTLKDNGFTETKSGNFQLIRSLDPTPQRNEGFKLKITITADLKELKMSITTANGLKPMNIFKNEQHEMSKEKYFFLMDGLISRGVLEKVE
>NZ_CP046108.1|WP_002356958.1|1224708_1225854_+|cysteine-desulfurase
MEPIYLDHAATTPLHPTVIQAMTENMQTTFGNPSSIHQFGRKAHGLLEEVRQTIAESLQAKPHEIIFNSGGTEGDNTAILAVAFSRQKEGKHIITTAIEHPAVLRTMEYLETLGFEVTYLPVNENGQISMDQFKKSLREETILVSMMYGNNEIGNRLPIAEVGAILKNHSAIFHTDAVQAYGSEVILPHELGIDLLSISAHKINGPKGVGFLFKSDAIQLPPLLHGGEQEEKRRAGTENLAGIIGMGTAVSLLTSAEKQARKTAYQSFQTIILKALEEANIDFSINGEPTNRLAHVLNLHLKGVPSDLLLMHLDLRGIAISTGSACTAGTVDPSHVLTAMYGENSSAIKESIRISFGYGNTPEEIATFSEVLVAVIQQLKK
>NZ_CP046108.1|WP_002356957.1|1223577_1224552_+|ribose-phosphate-diphosphokinase
MTENYQDDTLRIFSLNANRPLAEKIAASVGTELGKSTVRQFSDGEIQINIEESIRGDHVYIIQATNAPVNDHLMELLILIDALKRASAKTINVILPYYGYARQDRTAKPREPITAKLVANMLVEAGATRLLTLDLHTVQVQGFFDIPVDNLFTMPLFAHYYRQQALVGEEIVIVSPKNSGVQRARSLSEYLDATLAIVDHEEIDGVRQEGYVIGNVAGKKCILVDDILNTGQTLATAAEVLMKNGAQEVYACASHGLLSEGAKATLENAPIKEISITDSVYTTTDRQPATLNIISCAELMGEALLRIHENKPMSPLFRLEPKGE
>NZ_CP046108.1|WP_002356956.1|1222615_1223365_-|metal-ABC-transporter-ATP-binding-protein
MRKSFNLAVQALTVQYQGRTALNNIHVTIPSGKITGIIGPNGAGKSTFIKGLLGLIKTKERNVLLNNQAIDQQKTTIAYVEQRSALDLSFPISVFETVLLGTYPNLGLLKRPGKKEKQAAMAALKMVQLEDYAQRQIGELSGGQLQRVFIARVLAQGAEVIFLDEPFVGIDMSSEKVIMDILKSLKNQGKMIIIVHHDLHKVSHYFDELIVLKNRLIAAGPVEQTFTAETLQEAYGDLLGDLLIQGVAK
>NZ_CP046108.1|WP_002356974.1|1234741_1236160_+|cytochrome-ubiquinol-oxidase-subunit-I
MFDIVTLARIQFAMTTVFHFFFVPFSIGLALVVAIMETMYVVKKEERYRKMAKFWGNIFLLSFAVGVVTGIIQEFQFGMNWSDYSRFVGDIFGAPLAVEALLAFFLESTFLGLWIFTWDKMNPKVHVTFIWLVVFGSMMSAFWILVANSFMQHPVGYVINNGRAEMVDFVAVISNPKVWYEFSHVIMGAFTLGGMAVAGMAAFQLLKKRDISFHKASMRIGLWVTLFGSIGVLLAGDLQMKALIEGQPMKFAAMEGAYEDSDDPAAWTLIAWADEREHKQVFGIDIPYMLSILSYNKLSGSVDGMDTVNKRLVEKYGDDKNYYPPVNTLFWSFRIMAGFGALMLLVAALGLFFTRKKKPSLYEKKWMLWIVALCTFAPFLANTTGWLVTELGRYPWTVYGLFTIEQSVSPNVSVASLITSNVIYFLLFAGLGSVMVYLVILELRKGPDYEAKKLAKENEPALDPFDKGVFGE
>NZ_CP046108.1|WP_002356976.1|1236156_1237170_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MSTLQLLWFVLIGVLFSGFFFLEGFDFGVGMAVQTLAHNDDEKDQVVATIGPVWDGNEVWLLTAGGAMFASFPYWYASLFSGYYLILFTILFGLIIRGVSFEFRHNMPEGKRRRMWNWTLSIGSFLVPFFFGILFISLVQGMPLDANGNMHAQFTDYFNLFSIVGGVALTLLCYLHGMNYIALKTEGPIRERARNYAEILYGVLYVGLVVFAVLMYFKTDFYEKNFAVTLILTLAIVVLTVIANVGVFKRKEMLAFLASGLTLVVLVALLFSGLFPRVMIGSEGFDLLIKDATSTPYTLKIMTWISLSILPFVLAYTAWSYYIFRKRISQTAVPEGY
>NZ_CP046108.1|WP_002369918.1|1237174_1238908_+|thiol-reductant-ABC-exporter-subunit-CydD
MIDKDILQMPKIKKILVLLAGFSFLQAVFIIGQAFFLSKAIVGLWSGGHLNQQLQSILLFFIFYLGRHVITYFRERMLDTFSYERSKELREQLLTKIFRLGPNVVQKNGTGNMVTMALEGISQTENYLQLILTKMMNMMIIPWIILAFVFTQDIRSGVTLLIVFPIIIIFMIVLGYAAQSKADKQYAAFQMLSNHFIDSLRGIDTLKLFGLSKKYAGSIYHTSERFRKATISTLKIAILSTFALDFFTTLSVAVVAVFLGLSLLNGTILLFPALVTLILAPEFFLPIRDFSSDYHATLDGKNSFQAIQAVLALPEAEQTDVLTLDDWHQESQLSVTALNFSYEDATQEAIQSLQFSVDGRKKIGIIGASGSGKSTLINLLSGFLLPTEETSQLAINGQTIPHFLQKDWQKQILYIPQAPYIFQDTLANNIRFYTPEATDEAIQQAIQLVGLDELVKDLPEGIHTLIGESGRMLSGGQAQRVALARAFVDQKRHVLLFDEPTAHLDIETEVEMKERMLPLMNNHLVFFATHRLHWMEEMDYILVMEKGQLVEQGTLAELIEKDGYYVQLMKQMRGGRQ
>NZ_CP046108.1|WP_002369917.1|1238904_1240671_+|thiol-reductant-ABC-exporter-subunit-CydC
MMEKQPTTKDVWKNDQWVRPFLKRYKKTLYFALLLGFLTFFSAGALMFTSGYLISRAASLPENILLIYIPIVLTRAFGIGRPVFRYVERLTSHNWVLKMTSDLRLKLYNVLEKDAIFFKTKYRTGDILGLLSEDINHIQNLYLRTIFPTVIAWILYIFLVIALGFFSWWFALCMLLMLGVVVFLLPLVSVLVNGARQEKHKYAKNELYQTLTDNILGVSDWVFSQRGSEFVARYETDEANVRALDEKMKQFNRGRDFVLQLLFGVIAIAVLAWTSVRFPGNHGGAANWIGAFVLTVFPLIDAFAPLPAAAQETTIYKDSIRRFNELPEGEDDSTEAPVQPNGTSLSIEHLSFAYENQEKKVLNDLSLTIPEKQKLAILGRSGSGKSTLASLIRGDLRPTSGEILLGNIPTEAFGETMTEYIGVMHQAPYLFRTTILNNIRIGREEASEAEVWAVLEKVGLKEMVNQLPEGLQTMVDEAGLRFSGGERHRLALARILLQDTPIVLLDEPTTGLDPITEQQLLETFFEALKDKTVIWITHHLQGVTLMDQVIFIEDGQLEMSGTPEELLATNAHYQKLYRIDRGISSFEE
>NZ_CP046108.1|WP_002378476.1|1240750_1241731_-|polyprenyl-synthetase-family-protein
MNTFWKSFPDVERSLTETCELIEQTLHTRNEDIEEALVTLARSGGKLLRPAFFFLFAQLGDEEKQEKQQLLKIAASLEILHMATLIHDDIIDDSPLRRGAVTIQSQYGKDVAVYTGDLLFTEFFTLIADAMNGSEFMKINAQGMKRLLLGELDQMSHRFDRRMSIPAYLRSVNGKTAELFSLSCLEGAYFGHSSKEVQRLAKRIGRHIGIAFQVYDDILDYTADTETLKKPALEDLSQGVYTLPLLFAYQAAPDVFGPYLDKGRAITLEEAAEVAALVNDYHGVTEAQAFAKKVTNKAITDIQQLPDGTAKETLLSLTELLLHRSF
>NZ_CP046108.1|WP_002360016.1|1241852_1242758_+|prenyltransferase
MNREIFFELVELKAKTASVLPFLLGICFSWYQYGRLHVGYVLIFFIAMFIFNMAVDILDNYNDYHHATEVHDYKEKTNIIGRENLSLPLIRKMIFWMILVSALMGIGLSFIVGWPLLIMGLYCYLIGIFYSSGPKPLSSLPLGEVFSGFTMGFMITLICVYINTFEVFNWSAANLWGIFLVALPNTCYIANLMLANNICDLEEDENNKRYTLVHYLGKASSLKLFVGLNTIAMLAILLAVGLGLTPPTMLLMLLTLPFVRKQTQALLKEQVKSKTFVCAVKILAVGATAQVLFFAIGLWWL
>NZ_CP046108.1|WP_002360017.1|1242786_1243998_+|NAD(P)/FAD-dependent-oxidoreductase
MNKKHVVILGAGYAGLKTLRELQKGAKDVEITLVDRNNYHYEATDLHEVAAGTQPAEKITYNIMDVVDEKMTTFIQGTVKTIDAATQTVALEDGQTINYDYLVVSLGFESESFGIPGVQEHALQMVDVKTALNVYEHIQEQMRQYKATQNEEFLKIVVCGAGFTGIELLGSLVENKPKFAEIAGVSADQIQIYCVEAVTRLLPMFNEKLANYGVQLLKDSAIHLLLGKPIKEIKPGAVVYQDNEAGDLAELSAKTIIWTTGVSGSHVVGDSGFEARRGRVMVQPDLTDANHSNVYIIGDCSAVMDTETNRPYPTTAQIALKMGAHAAKNIQAQLKGEATKPFSFKSQGSVCSVGNTRALGIVGKTDIKGYPASFMKKIIMNKALFETGGTKEMMAKGRFDLYH
>NZ_CP046108.1|WP_002364367.1|1244311_1246735_+|DNA-translocase-FtsK
MAQKRATNKKKSTTKKKTKKQQQQQERLNYMFLGLIFILFGVFGLFRLGFLGTLLANCLRLVVGNTFPFAAILLILYGLLVMIYGKDFPLKRGRPIFGAVLIYISVLLFFHAFMFRNVSGSQPDILGNTWEFLQSDLKANQVTQNVGGGMIGALLYQGTYFLVAQFGSYLIATLLLLAGIFLMSMWDFQQIVDHFQSIQDRLSHVSAKSQARQEEKEAKRAAKKEAKAAERQAKIEAAAQQKLQERERMEQAAAERLTKTPVETHQPMVEEPAAPTPVQIDSFQQQNQAMPVPPIAATKPQREQEEEAADEAGVLEFEISEEAEDRDYQLPPTDLLDTIQATDQSGEYEKIEKNIGVLEQTFKSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNSAISTVSFRDIVEAQPSHPDKLLEVPLGRDISGMVQTADLSKMPHLLIAGSTGSGKSVAINGIITGILMQAKPHEVKLMMIDPKMVELNVYNGIPHLLTPVVTNPRKAAQALQKVVQEMEFRYEKFAATGVRNITGYNQLIQQKNAEDGENRPILPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDTNGAEKLLGRGDMLFLPMGENKPIRIQGAFISDQEVERVVAFVTDQQEAEYQESMMPTDEPTTSGGGEAPQDELFEEAKNLVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVIGPSEGSKPRKVFLQAESEEAATETPEQ
>NZ_CP046108.1|WP_002356983.1|1246864_1247566_+|GntR-family-transcriptional-regulator
MRRKSVLYLEVADQIKEDILSGKYPVGTFLPTETELEEMFNVSKITIRRAIEMLATEEFVEKKSGRGTTVLSNRPYNKLSKAGTFTEFLNESGQKVTKKVLQVENLTLSKEMPAYQFLGEEVVHLSRLYLIDEQPYIYFNYYLPAAMKDVSLTEYKEESLYRLMDRHAIEIYKFEDRFEVATLTEAEQKMLQTTETTGLKRIRRSLSPTGRCVEYSEAIYNTKIHPYVIEYEA
>NZ_CP046108.1|WP_002372053.1|1247683_1248433_+|ABC-transporter-ATP-binding-protein
MLEVQNLKKVYGNEIKYEALKGINLTVQDGEFIGIMGPSGSGKSTLLNLLATIDSPTDGEILLNGKNPNNLNQEQIAKFRRTELGFVFQNFNLMPTLTVEENIILPLTLDGEKVSVMKRQLAELSERLGINHLLKKRIAEISGGQAQRVAVARAMIHHPQLLLADEPTGNLDTKSSKDVMGLLQQLNEEEAATILMVTHDPLAASYCKRIVFIKDGELIDEIVQNGNQKEFYDLIMVKLAEIEGVDNEF

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Crispr_ID: NZ_CP046108_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046108_3

2514314-2515141

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRISPRCasFinder
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CRT
GTTTTAGAGTCATGTTGTTTAGAATGGTACCAAAAC	PILER-CR

12 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP046108_3

>merge|NZ_CP046108|3|2514314-2515141|CRISPRCasFinder,CRT,PILER-CR
CGTATCTGCGAAAACTAAACAACATGACTCTAAAACATATGTAAATCATAATGAGCATTTACATTGGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCAAGCGATGGAGCAGGTTGGTCTGCTATGAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGAAACTTGATGTGCTACACCTTTAGCCCCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGAAAGCGTTGTGTAATGTGTCCATTTCTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCGTACTAAAGGTCATGTAATCTTACCAATCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACATTTCACCTTCTGTTTTAGAAGCTGCTTTAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCAACAATTTCCACCATACGTTTTTTCTCGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGCATATCAAGCGCACTACTTAAATGAAAACGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCTATAATGCCTGTGAGTAGCGTGTGTGTGCGTTTTGGTACCATTCTAAACAACATGACTCTAAAACCCCGTCTGTAATACACGTAACAACAAGCCAGTTTTGGTACCATTCTAAACAACATGACTCTAAAACAGAAAACTATACTCATATTTTTAAAGGTGTGTTTTGGTACCATTCTAAACAACATGACTCTAAAACGATAACTTAGAAAAGATGCAGGATGTTTTTGTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP046108|3|3|2514314-2515141|CRISPRCasFinder
CGTATCTGCGAAAACTAAACAACATGACTCTAAAAC	ATATGTAAATCATAATGAGCATTTACATTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAAGCGATGGAGCAGGTTGGTCTGCTATGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAAACTTGATGTGCTACACCTTTAGCCCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAAAGCGTTGTGTAATGTGTCCATTTCTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CGTACTAAAGGTCATGTAATCTTACCAATC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATTTCACCTTCTGTTTTAGAAGCTGCTTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAACAATTTCCACCATACGTTTTTTCTCGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATATCAAGCGCACTACTTAAATGAAAAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAACTATACTCATATTTTTAAAGGTGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAACTTAGAAAAGATGCAGGATGTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP046108|3|2|2514314-2515141|CRT
CGTATCTGCGAAAACTAAACAACATGACTCTAAAAC	ATATGTAAATCATAATGAGCATTTACATTG
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAAGCGATGGAGCAGGTTGGTCTGCTATGA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAAACTTGATGTGCTACACCTTTAGCCCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GAAAGCGTTGTGTAATGTGTCCATTTCTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CGTACTAAAGGTCATGTAATCTTACCAATC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	ATTTCACCTTCTGTTTTAGAAGCTGCTTTA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAACAATTTCCACCATACGTTTTTTCTCGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATATCAAGCGCACTACTTAAATGAAAAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAACTATACTCATATTTTTAAAGGTGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAACTTAGAAAAGATGCAGGATGTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

>NZ_CP046108|3|2|2514710-2515141|PILER-CR
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CAACAATTTCCACCATACGTTTTTTCTCGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GCATATCAAGCGCACTACTTAAATGAAAAC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CTATAATGCCTGTGAGTAGCGTGTGTGTGC
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	CCCGTCTGTAATACACGTAACAACAAGCCA
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	AGAAAACTATACTCATATTTTTAAAGGTGT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC	GATAACTTAGAAAAGATGCAGGATGTTTTT
GTTTTGGTACCATTCTAAACAACATGACTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046108.1\|WP_002364837.1\|2524342_2525992_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NZ_CP046108.1\|WP_002386142.1\|2508059_2509580_-\|phosphoglucomutase	unknown	unknown	gnl\|CDD\|215211
NZ_CP046108.1\|WP_002381241.1\|2512918_2513932_+\|acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|226122
NZ_CP046108.1\|WP_002355509.1\|2509613_2510069_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_CP046108.1\|WP_002355517.1\|2503978_2506165_-\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NZ_CP046108.1\|WP_002355518.1\|2503574_2503916_-\|YlbF-family-regulator	unknown	unknown	gnl\|CDD\|237467
NZ_CP046108.1\|WP_002361240.1\|2507494_2508049_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_CP046108.1\|WP_010784993.1\|2523499_2524234_-\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NZ_CP046108.1\|WP_025188088.1\|2526171_2527716_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	unknown	unknown	gnl\|CDD\|237588
NZ_CP046108.1\|WP_002364832.1\|2515233_2515893_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_CP046108.1\|WP_002364834.1\|2516219_2517086_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_CP046108.1\|WP_002364822.1\|2502183_2503419_-\|DNA-repair-exonuclease	unknown	unknown	gnl\|CDD\|277319
NZ_CP046108.1\|WP_002364833.1\|2515893_2516223_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP046108.1\|WP_002358655.1\|2521950_2523366_-\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|130941
NZ_CP046108.1\|WP_002355504.1\|2521572_2521806_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046108.1\|WP_002363150.1\|2511728_2512682_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_CP046108.1\|WP_002394646.1\|2506519_2507371_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP046108.1\|WP_002364839.1\|2527844_2528267_+\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|223372
NZ_CP046108.1\|WP_010785195.1\|2517086_2521100_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP046108.1\|WP_002364825.1\|2510210_2511728_-\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328

Protein	Function_ID	Function_description	E-value
NZ_CP046108.1\|WP_002364837.1\|2524342_2525992_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.27874e-136
NZ_CP046108.1\|WP_002386142.1\|2508059_2509580_-\|phosphoglucomutase	gnl\|CDD\|215211	PLN02371, PLN02371, phosphoglucosamine mutase family protein.	0
NZ_CP046108.1\|WP_002381241.1\|2512918_2513932_+\|acyltransferase-family-protein	gnl\|CDD\|226122	COG3594, NolL, Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism].	2.63008e-11
NZ_CP046108.1\|WP_002355509.1\|2509613_2510069_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	1.0984e-46
NZ_CP046108.1\|WP_002355517.1\|2503978_2506165_-\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NZ_CP046108.1\|WP_002355518.1\|2503574_2503916_-\|YlbF-family-regulator	gnl\|CDD\|237467	PRK13676, PRK13676, YlbF/YmcA family competence regulator.	2.56028e-37
NZ_CP046108.1\|WP_002361240.1\|2507494_2508049_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.85004e-26
NZ_CP046108.1\|WP_025188088.1\|2526171_2527716_+\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase	gnl\|CDD\|237588	PRK14022, PRK14022, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.	0
NZ_CP046108.1\|WP_002364832.1\|2515233_2515893_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.31098e-118
NZ_CP046108.1\|WP_002364834.1\|2516219_2517086_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.59266e-115
NZ_CP046108.1\|WP_002364822.1\|2502183_2503419_-\|DNA-repair-exonuclease	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.06439e-49
NZ_CP046108.1\|WP_002364833.1\|2515893_2516223_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.08189e-44
NZ_CP046108.1\|WP_002358655.1\|2521950_2523366_-\|dipeptidase-PepV	gnl\|CDD\|130941	TIGR01886, Beta-Ala-Xaa_dipeptidase, dipeptidase PepV. This model represents a small clade of dipeptidase enzymes which are members of the larger M25 subfamily of metalloproteases. Two characterized enzymes are included in the seed. One, from Lactococcus lactis has been shown to act on a wide range of dipeptides, but not larger peptides. The enzyme from Lactobacillus delbrueckii was originally characterized as a Xaa-His dipeptidase, specifically a carnosinase (beta-Ala-His) by complementation of an E. coli mutant. Further study, including the crystallization of the enzyme, has shown it to also be a non-specific dipeptidase. This group also includes enzymes from Streptococcus and Enterococcus. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP046108.1\|WP_010784993.1\|2523499_2524234_-\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	5.67666e-91
NZ_CP046108.1\|WP_002363150.1\|2511728_2512682_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	2.40789e-140
NZ_CP046108.1\|WP_002394646.1\|2506519_2507371_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.10552e-91
NZ_CP046108.1\|WP_002364839.1\|2527844_2528267_+\|cytidine-deaminase	gnl\|CDD\|223372	COG0295, Cdd, Cytidine deaminase [Nucleotide transport and metabolism].	9.64506e-24
NZ_CP046108.1\|WP_010785195.1\|2517086_2521100_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP046108.1\|WP_002364825.1\|2510210_2511728_-\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.70713e-168

>NZ_CP046108.1|WP_002381241.1|2512918_2513932_+|acyltransferase-family-protein
MENDKRIYKWDNVKLFLIFLVIFGHILDREASPSRLMETINFWIYSFHMPAFIFVSGLFSKHAIKQRKYLRLLSFVWLYLLAKLLITLANFAFANKMNFDLLNETGVPWYLLSLASFYLITIFLQRVQPKIMLPIIIVIGCASGYLPVEGFLSLGRTLGFFPFFYCGYLMDIQKLQTFLDHRKVKWAAIGVILSSFLFVNSQWSLATKFWGFLTGWASYAEISPAFEYSSFIQLFFYVAAALVSLSWFALLPKRKLPLSALGKDTLYPYLLHMPLIILLESGLQLDTLFKEWFTFRILALFFLALFILAITNMPVVKRGADYLFNPQSIMIPKKIYK
>NZ_CP046108.1|WP_002363150.1|2511728_2512682_-|ABC-transporter-ATP-binding-protein
MIKFQNVSKVYQENAVLSDVNLTIQQGEFFVLVGPSGSGKTTTLKMINRLIEPTTGEVALNEQAVTNYPLRELRLKIGYVLQQIALFPNLTVAENIELIPEMKKWPKEQRRERTIELLKKVQLDPEEYLHRKPAALSGGEQQRIGILRAIAAEPEVILMDEPFSALDPISRHHLQRLVKELHQELASTIVFVTHDMNEALLLGERICIMDAGKIIQVDTPEAIQKHPKNNFVGQFFKQSSPELANYCGADLTAFLEAADETIEPVPTVFMETNLKEIVQLINAQEKANLVEKQQVLGCITSKTITRFMEQLLESEGQ
>NZ_CP046108.1|WP_002364825.1|2510210_2511728_-|ABC-transporter-permease/substrate-binding-protein
MQALIETFFARKEEYLQALIEHMQLSFISLLFAALIAIPLAIYLTSHRKLAESLLQVTGIFQTIPSLALLGLLIPLIGIGRPPAIVALVIYALFPILQNTYTGLTEIDPSLEEAAEAFGMSKKEKLFKFELQMALPFIISGIRTATVLIIGTATLAALIGAGGLGTFILLGIDRNNLSLIFIGALSSAALAVLFNYGIHWLEKANGRRLIIGGTILGLLLGGSFFWNQQTSSKEKQLTIAGKLGAEPDIIINMYKALIEENSDIQVTLKPNFGKTTFLYNALKSDEIDLYPEFTGTVIETFLKNPPQLDNQPQVVYEAARAGLKKQENLTLLKPMRYENTYAVAVKRSFAKAHQLKTISDLQKISNQLKAGFTLEFIDRQDGYKGLQEKYHLNLNVQSMEPALRYQAINNGEVNVIDAYSTDSELKQYDLVTLEDDQALFPPYQGAPLIKTATLEKYPELAEILNKLAGKISEEEMSEMNYQVNVEGQDPSIVAKDYLKEKNLLK
>NZ_CP046108.1|WP_002355509.1|2509613_2510069_-|arginine-repressor
MKKAERQRLIKQLIMQQEIETQDELITRLEELGVRATQATVSRDIREMSIVKTHGADGRVKYAIFSQAQGTSSEEKLRESVKDSVVRMERVQFIVILHTEMGNADVVSNFLDEVAYPEVAGTVAGADTIIVITRSEEDAEHFIERIENMIF
>NZ_CP046108.1|WP_002386142.1|2508059_2509580_-|phosphoglucomutase
MVELKALQNGSDIRGIALDTEEQTATLTATAVAEIAVGVVRWLQDKKQLPRKAQQRLTIAIGHDSRLTAEPIKQALVDTFLSLGIQVIDVGLATTPAMFMATQFPTLQCDAAIMITASHLPYYFNGLKFFTAEGGAEKEDIRYILSHTDPLTANENGTLMKQELLPIYAEHLVAKIRQGIHSPEEKPLQGFRIIVDAGNGAGGFFAEQVLQVLGADTTGSQFLEPDGHFPNHVPNPDNSEAMKSIQTAVLANQADLGIIFDTDVDRSAVVDQSGEVLNRNNLIAVLAAIVLKEAPGSYIVTNSPTSSHLKTFIEEKGGQQIRYISGYRNVINKMIELNHGGFQTPLAIETSGHAAFQENYNLDDGAYVVAKILMLLPELKQNNQTLGDLIATLKQPAETNEFRFKITAEDVTCYGQQVLRDFELFVENQADFAVDRENQEGVRGNVSGQYGSGWFLLRLSLHEPLLVLQVENDQSDKNACVIEKIATFLQKYEEIDSQQIENNLGN
>NZ_CP046108.1|WP_002361240.1|2507494_2508049_-|GNAT-family-N-acetyltransferase
MENVLKGKHIGFSHFREEYIEHIAKQQWDNELLRHLSWDALHPWGLEEWKDFTINKGEDDRFLFAILENTTEKFIGWVSLSDVQLKNRGANLGIAILQKEQRGQGYGFEAVSLICKFAFYELGLHKIRLAVNSNNQKAIHVYEKVGFKKEGIDREALFQDGQWLDIYNYGILQKEWLQMIKAES
>NZ_CP046108.1|WP_002394646.1|2506519_2507371_+|RluA-family-pseudouridine-synthase
MRLPENFSTMTVKELLENEWLVPRKVRHFLRTRKNVKINGETAAFHFPVQAGDCVTLTFEETDYVRPTIHLGEATRVKVLYEDEHLMIVNKPYGIKTHPNQPQETDTLLNHVAAYLAEKNQVPYVVHRLDKETSGAIVFAKNPFVLPILGRLLETKQIYRQYQAIVAGHFNQKEQTINQPIGRDRHDRRKRRIDPQKGDSAITHVQVVQALSNNQTAVTCVLETGRTHQIRVHLASEGHPIIGDPLYNPKSQAARLMLHASQLHLLHPFTKKQIVVTAAPGLW
>NZ_CP046108.1|WP_002355517.1|2503978_2506165_-|PBP1A-family-penicillin-binding-protein
MDNLKQFFSKVGVGLRHFWTWIKPYLIQFHQARKRIWKKYQINKIFLLIGLVVALGASIYLFYLAKSANVETLKSGLSESTRVYDESGEEVGKLFGQKGTFVELDNISPYIQDAVISTEDRGFYQHKGYSIKGIARAVVGKLTFGKIGGGGGGSTITQQLAKNAYLTQEQTLDRKARELFLAIEIEKKYSKKDILAMYLNNSYFGNGVWGVQDAARKYFGVDASQVTVGEAATLAGMLKGPGIYNPIDYIDNATARRNTVLQLMVDNKKLSQEEANQEASVNLASLLNDTYVGDENSYKYPYYFDAVIDEAVNRYKFKEEDILNKGYKIYTSLNQKYQDAMDATYKNDALFPPNAEDGAMVQSGSVAIDPKTGGVQALVGGRGEHVYRGFNFATQTKRSPGSSLKPISVYTPALEAGYKPDSVLEDKPQDYYPAQNYSRTYSGEVPMYQALGESLNLPAVWLLHQIGLDKGYEKTEKFGIPLSEKDRYYGLALGGLQTGVSPLTMAGAYSAFANEGYKTETHLITKIVDSTGAIVVDNTKVKKEQVITKDVADGITSMLLGVFSSGSGVNAQPAGYVMAGKTGTTETNFDSSKTNDQWVIGYTPEVVIATWLGFQETSKTHYLEGSSATYASQVFNSQASGILPQVKQAQFPVADAYATGGKVVDSNDSLTGGANSNWRDNLKDFGNSVQDGASNFGDTLNEVGGQIKDGAKKVKDKIEGIFGGLLGN
>NZ_CP046108.1|WP_002355518.1|2503574_2503916_-|YlbF-family-regulator
MSNIYDTANQIERELRELDEFKALQAAYEEVKADEAAYTLFKEFQGFQQGLQEKQMRGEEFTDEDAEKAQSIATKVQETAVINELMQKEQAFSLVVNDLNRIIMTPVRDMYND
>NZ_CP046108.1|WP_002364822.1|2502183_2503419_-|DNA-repair-exonuclease
MKLLHTADLHMDRSFEGLTGIPTALAKRLREANQQLLMNIVTVAIREAVDLVIFAGDTFHQSQTSISMQAQLMAALEQLKQAEIPVILTFGNHDYYKKDRYWFSFPDNVFLFEKEMVETLYFETKAGEQVAVSGFSYEHPWIDENKALEFPIKQAESDIHIGIYHGDTSRKAQQNYAPFTWKDLKATGYNYWALGHIHQPQIVSEQPLIVYPGTPQGHTKKEQSLQGVAVVTLSQNQATVQFEKVAEIDWTNEEVSLAQCRDTQSVLSYLETSLLTKWHAHQQQQLMALTLKETQHLDVTVVQAIVNGELLSYLQQQLLQKTQGDFFVYRLILQAEEPTKEPIYLSASPNLLTALEKTYLDPVIFEDTTKELLRYPEFAGIFSMDEQWRLESLRLAHEQINEDFTIQEDPL
>NZ_CP046108.1|WP_002364832.1|2515233_2515893_-|type-II-A-CRISPR-associated-protein-Csn2
MRVNFSLLEEPIEIEKATFLTIKDVQTFAHLVKLIYQYDGENELKLFDAQQKGLKPTELFVVTDILGYDVNSAATLKLIYGDLEAQLNDKPEVKSMIEKLTGTISQLIGYELLEHEMDLEEDGITVQELFKALGIKIETTSDTIFEKVMEITQVHRYLSKKKLLIFINACTYLTEDEVQQVVEYISLNNVDVLFLEQRVVQNRFQYILDENFYLSYEKA
>NZ_CP046108.1|WP_002364833.1|2515893_2516223_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRLLLMFDMPTDTASDRKAYRKFRKFLINEGFIMHQFSVYSKILLNDTANKAMLARLKQNNPQRGLITLLNVTEKQFSRMIYLHGEQDNRVANSDERIVFLGEE
>NZ_CP046108.1|WP_002364834.1|2516219_2517086_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNKHSKLSYKNNHLVFKAIDHQELIHLSEIDVLLLETTDISLTTMLLKRLIDEKILVLFCDDKRLPIGKILPFYGRHDSSLQLTRQLAWTEERKGQVWTAIIAQKITNQSLHLAQRDYGQKAAALLAMRAELRLFDPANREGHAARSYFNTLFGNDFTREQENDINAGLNYGYTLLLSIFARELVQTGCFTQLGLKHANQFNDFNLASDLMEPFRPLVDQIIYENRKEAFPIMKRKLFALFMNTYMYKKKQMFLTNIATDYTKHVVKVLNQEEEGVPEFGI
>NZ_CP046108.1|WP_010785195.1|2517086_2521100_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKDYVIGLDIGTNSVGWAVMTEDYQLVKKKMPIYGNTEKKKIKKNFWGVRLFEEGHTAEDRRLKRTARRRISRRRNRLRYLQAFFEEAMTDLDENFFARLQESFLVPEDKKWHRHPIFAKLEDEVAYHETYPTIYHLRKKLADSSEQADLRLIYLALAHIVKYRGHFLIEGKLSTENISVKEQFQQFMIIYNQTFVNGESRLVSAPLPESVLIEEELTEKASRTKKSEKVLQQFPQEKANGLFGQFLKLMVGNKADFKKVFGLEEEAKITYASESYEEDLEGILAKVGDEYSDVFLAAKNVYDAVELSTILADSDKKSHAKLSSSMIVRFTEHQEDLKKFKRFIRENCPDEYDNLFKNEQKDGYAGYIAHAGKVSQLKFYQYVKKIIQDIAGAEYFLEKIAQENFLRKQRTFDNGVIPHQIHLAELQAIIHRQAAYYPFLKENQEKIEQLVTFRIPYYVGPLSKGDASTFAWLKRQSEEPIRPWNLQETVDLDQSATAFIERMTNFDTYLPSEKVLPKHSLLYEKFMVFNELTKISYTDDRGIKANFSGKEKEKIFDYLFKTRRKVKKKDIIQFYRNEYNTEIVTLSGLEEDQFNASFSTYQDLLKCGLTRAELDHPDNAEKLEDIIKILTIFEDRQRIRTQLSTFKGQFSAEVLKKLERKHYTGWGRLSKKLINGIYDKESGKTILGYLIKDDGVSKHYNRNFMQLINDSQLSFKNAIQKAQSSEHEETLSETVNELAGSPAIKKGIYQSLKIVDELVAIMGYAPKRIVVEMARENQTTSTGKRRSIQRLKIVEKAMAEIGSNLLKEQPTTNEQLRDTRLFLYYMQNGKDMYTGDELSLHRLSHYDIDHIIPQSFMKDDSLDNLVLVGSTENRGKSDDVPSKEVVKDMKAYWEKLYAAGLISQRKFQRLTKGEQGGLTLEDKAHFIQRQLVETRQITKNVAGILDQRYNANSKEKKVQIITLKASLTSQFRSIFGLYKVREVNDYHHGQDAYLNCVVATTLLKVYPNLAPEFVYGEYPKFQTFKENKATAKAIIYTNLLRFFTEDEPRFTKDGEILWSNSYLKTIKKELNYHQMNIVKKVEVQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVLFTHEKGKKPLIKQEILGITIMEKTRFEQNPILFLEEKGFLRPRVLMKLPKYTLYEFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKQCLLPNQSESLTYVEQHQPEFQEILERVVDFAEVHTLAKSKVQQIVKLFEANQTADVKEIAASFIQLMQFNAMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVVD
>NZ_CP046108.1|WP_002355504.1|2521572_2521806_-|hypothetical-protein
MSETLIVNYLIKGRVKMNVEELVQKAKDLIGEGNVEHAQQFIEEHKDELGEHYHKITAMLADTTTDGLFDKIKGLFQ
>NZ_CP046108.1|WP_002358655.1|2521950_2523366_-|dipeptidase-PepV
MTIDWTKEVEARKDDLLEDLQNLLRINSERDDAQATPEAPFGPGPVAGLKHMLAYGERDGFTVKNVDNYAGHIEYGEGDETLGIFGHMDVVPAGDGWETDPYEPVIKDGKIYARGASDDKGPSMAAYYAMKIIKELGLPVSKKIRFVVGSDEESGWGDMDYYFQHEEAPDFGFSPDAEFPIINGEKGNVTIRLTFRGGNGADYKLESFKSGLRENMVPGTADAVVTAASADEAASLAASFETFIKQEAKISGNAELSDKTVTFHVVGKGAHGASPQSGINAATFLATFLNDYSFAEGAYSFINTIAEFIHEDFYGEKLGVAFEDEKMGKLTMNAGIVNFDPENPENSLVTLNFRYPKGTSAEELQAKVQATVGETVTATQGDRNQEPHYVPVDDPLVATLLQVYEDHTGEKGQEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEFMELDDLFRAAAIYADAIYRLAK
>NZ_CP046108.1|WP_010784993.1|2523499_2524234_-|rRNA-pseudouridine-synthase
MRLDKFLADVGIGSRKEIKQLLKKKVVTVNGDVVKEAKTQVNEETDQIALMGEILTYQKFFYYMLHKPQGVISATEDQRDETVIDLLTDQDYRADLFPVGRLDKDTEGLLLLTNDGQLAHQLLSPKKHVDKEYLAEVEGLVTAEDCQLFAQGFALKDGEMVKPSRLVIETINEEEGTSVVRLVIQEGEFHQVKRMLATVGKPVTYLKRLRMGELWLDETLELGEYRPLTEAELQQLQPKQSYLN
>NZ_CP046108.1|WP_002364837.1|2524342_2525992_-|polysaccharide-biosynthesis-protein
MINQPNSVDQPILTNQEKMVKGSAWMTASNIISRMLGAIYIIPWYAWMGEHGNEANSLFSMGYTIYALFLMISTAGIPGAIAKQTSHYNSLNEYKISRQLFYRALQLMGGLGVVFAIVMYLASPALAALSGGGPELVPTMRSLSLAVLVFPSMSVIRGYFQGNQEMMPFALSQIVEQVARVFYMLLTAFIIMKVFEGNYVTAVTQATFAAFIGMLASFAVLGYYMYKQKPLFDYLEEHSANEHEIAPKELLIETFKEAIPFIVVGSGVTVFKLVDQFTFSNFMRLFTDYSDTQLRELFGIFNANPDKLTMIVVALATSISATGLPLITEAVTLKNHRELARLISNNLQLFVFVMLPATFGMIVLAQPLYTVFYMPDALGTSLLVQACYASLFLGLYMLVSNMLMGMYENRDAMRYLGIGLAVKLIVQFPAIRLFEVYGPLLATMIGFTVSCVLILRRIRQVTRFNYKLTLRRTLLMFCITVIMMIIALIFRQFLYLFLDPTRRFQAFIIVVIVAAAGGAFYGYSVLKIRLADRLLGKNAAKLRAKFNIK
>NZ_CP046108.1|WP_025188088.1|2526171_2527716_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L--lysine-ligase
MKRLEAKKVTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTVLDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAKMIIDK
>NZ_CP046108.1|WP_002364839.1|2527844_2528267_+|cytidine-deaminase
MDIWKKMYEYAKKEYHPQEVTPFIYTHHVVCALEAEDGQLFTGFCFESCCGVLDLCAERVAALNMYADSGQTVIKRIITFRDDVPNGISGMPCGACRELLLQLSPKNADTEILVDYQKREIVRLKELMPKWWGWSRYTND

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	39957-39986	0	1.0
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	37120-37149	0	1.0
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	53177-53206	0	1.0
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP041739	Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence	39957-39985	0	1.0
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	37120-37148	0	1.0
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	53178-53206	0	1.0
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MK721190	Enterococcus phage vB_EfaS_Ef6.4, complete genome	26991-27020	0	1.0
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	GQ478085	Enterococcus phage phiFL2B, complete genome	14692-14721	0	1.0
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_013643	Enterococcus phage phiFL2A, complete genome	14103-14132	0	1.0
NZ_CP046108_3	3.7\|2514746\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514746-2514775	30	GQ452243	Enterococcus phage phiEf11, complete genome	12574-12603	0	1.0
NZ_CP046108_3	3.7\|2514746\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514746-2514775	30	NC_028671	Enterococcus phage vB_EfaS_IME197, complete genome	11483-11512	0	1.0
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP022484	Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence	35711-35740	1	0.967
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	48629-48658	1	0.967
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	41683-41712	1	0.967
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	53005-53034	1	0.967
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP022484	Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence	35711-35739	1	0.966
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	48630-48658	1	0.966
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP042217	Enterococcus faecalis strain L8 plasmid pL8, complete sequence	41684-41712	1	0.966
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	53006-53034	1	0.966
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MK721187	Enterococcus phage vB_EfaS_Ef6.1, complete genome	27427-27456	1	0.967
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	GQ478087	Enterococcus phage phiFL3B, complete genome	15516-15545	1	0.967
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_013648	Enterococcus phage phiFL3A, complete genome	15210-15239	1	0.967
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	GQ452243	Enterococcus phage phiEf11, complete genome	39497-39526	1	0.967
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_028671	Enterococcus phage vB_EfaS_IME197, complete genome	39141-39170	1	0.967
NZ_CP046108_3	3.7\|2514746\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514746-2514775	30	KJ608188	Enterococcus phage EFC-1, complete genome	28943-28972	1	0.967
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MT119359	Enterococcus phage heks, complete genome	31812-31841	2	0.933
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MK125140	Enterococcus phage Nonaheksakonda, complete genome	28370-28399	2	0.933
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	NC_042023	Enterococcus phage phiSHEF5, complete genome	14060-14089	2	0.933
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	GQ478082	Enterococcus phage phiFL1B, complete genome	14692-14721	2	0.933
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	GQ478083	Enterococcus phage phiFL1C, complete genome	14426-14455	2	0.933
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_013646	Enterococcus phage phiFL1A, complete genome	14445-14474	2	0.933
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	44693-44722	3	0.9
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP015884	Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence	44693-44721	3	0.897
NZ_CP046108_2	2.7\|1234271\|29\|NZ_CP046108\|CRISPRCasFinder	1234271-1234299	29	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	726854-726882	5	0.828
NZ_CP046108_2	2.8\|1234270\|30\|NZ_CP046108\|CRT	1234270-1234299	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	726854-726883	5	0.833
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MH375074	Enterococcus phage LY0323, complete genome	11789-11818	5	0.833
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	MK982307	Enterococcus phage MSF2, complete genome	33836-33865	5	0.833
NZ_CP046108_3	3.3\|2514482\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514482-2514511	30	KX284704	Enterococcus phage SANTOR1, complete genome	25134-25163	5	0.833
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP023544	Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence	42911-42939	6	0.793
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP017872	Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence	31018-31046	6	0.793
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NC_022355	Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence	42878-42906	6	0.793
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP045793	Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence	32830-32858	6	0.793
NZ_CP046108_2	2.5\|1234139\|29\|NZ_CP046108\|CRISPRCasFinder	1234139-1234167	29	NZ_CP023546	Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence	33401-33429	6	0.793
NZ_CP046108_2	2.8\|1234270\|30\|NZ_CP046108\|CRT	1234270-1234299	30	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	41998-42027	6	0.8
NZ_CP046108_2	2.8\|1234270\|30\|NZ_CP046108\|CRT	1234270-1234299	30	MT708547	Klebsiella phage Muenster, complete genome	164106-164135	6	0.8
NZ_CP046108_2	2.8\|1234270\|30\|NZ_CP046108\|CRT	1234270-1234299	30	AB897757	Klebsiella phage K64-1 DNA, complete genome	42006-42035	6	0.8
NZ_CP046108_3	3.1\|2514350\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514350-2514379	30	MK867354	Synechococcus phage S-SCSM1, complete genome	151260-151289	6	0.8
NZ_CP046108_3	3.6\|2514680\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514680-2514709	30	NZ_KJ776578	Clostridium botulinum strain CDC3875 plasmid pCDC3875, complete sequence	26197-26226	6	0.8
NZ_CP046108_3	3.6\|2514680\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514680-2514709	30	NZ_KJ776580	Clostridium botulinum strain CDC5900 plasmid pCDC5900, complete sequence	31008-31037	6	0.8
NZ_CP046108_2	2.1\|1234072\|30\|NZ_CP046108\|PILER-CR,CRT	1234072-1234101	30	NC_019534	Bacteroides fragilis plasmid pBFUK1, complete sequence	7141-7170	7	0.767
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP023544	Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence	42911-42940	7	0.767
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP017872	Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence	31018-31047	7	0.767
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NC_022355	Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence	42878-42907	7	0.767
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP045793	Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence	32829-32858	7	0.767
NZ_CP046108_2	2.2\|1234138\|30\|NZ_CP046108\|PILER-CR,CRT	1234138-1234167	30	NZ_CP023546	Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence	33400-33429	7	0.767
NZ_CP046108_2	2.4\|1234073\|29\|NZ_CP046108\|CRISPRCasFinder	1234073-1234101	29	NC_019534	Bacteroides fragilis plasmid pBFUK1, complete sequence	7142-7170	7	0.759
NZ_CP046108_2	2.4\|1234073\|29\|NZ_CP046108\|CRISPRCasFinder	1234073-1234101	29	NZ_CP034946	Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence	4704-4732	7	0.759
NZ_CP046108_2	2.4\|1234073\|29\|NZ_CP046108\|CRISPRCasFinder	1234073-1234101	29	MT188223	Acinetobacter phage vB_AbaM_D22, complete genome	95957-95985	7	0.759
NZ_CP046108_2	2.6\|1234205\|29\|NZ_CP046108\|CRISPRCasFinder	1234205-1234233	29	NC_009453	Arthrobacter sp. Rue61a plasmid pAL1, complete sequence	17952-17980	7	0.759
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	MH179477	Aeromonas phage 60AhydR15PP, complete genome	151274-151303	7	0.767
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_014635	Aeromonas phage phiAS4, complete genome	51356-51385	7	0.767
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NC_020879	Aeromonas phage Aes012, complete genome	116920-116949	7	0.767
NZ_CP046108_3	3.4\|2514548\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514548-2514577	30	NZ_CP025802	Yersinia ruckeri strain SC09 plasmid pLT, complete sequence	26191-26220	7	0.767
NZ_CP046108_3	3.6\|2514680\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514680-2514709	30	NZ_CP014218	Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence	9126-9155	7	0.767
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	GQ478087	Enterococcus phage phiFL3B, complete genome	31016-31045	7	0.767
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_013648	Enterococcus phage phiFL3A, complete genome	30317-30346	7	0.767
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_AP017969	Fusobacterium varium strain Fv113-g1 plasmid pFV113-g1-1, complete sequence	56397-56426	7	0.767
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	MH319764	Marine virus AG-345-P14 Ga0172274_11 genomic sequence	36540-36569	7	0.767
NZ_CP046108_3	3.12\|2515076\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515076-2515105	30	MN694628	Marine virus AFVG_250M527, complete genome	27249-27278	7	0.767
NZ_CP046108_3	3.12\|2515076\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515076-2515105	30	MN856107	Bacteriophage sp. isolate 216, complete genome	5132-5161	7	0.767
NZ_CP046108_2	2.1\|1234072\|30\|NZ_CP046108\|PILER-CR,CRT	1234072-1234101	30	NZ_CP034946	Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence	4703-4732	8	0.733
NZ_CP046108_2	2.1\|1234072\|30\|NZ_CP046108\|PILER-CR,CRT	1234072-1234101	30	MT188223	Acinetobacter phage vB_AbaM_D22, complete genome	95957-95986	8	0.733
NZ_CP046108_2	2.3\|1234204\|30\|NZ_CP046108\|PILER-CR,CRT	1234204-1234233	30	NC_009453	Arthrobacter sp. Rue61a plasmid pAL1, complete sequence	17952-17981	8	0.733
NZ_CP046108_2	2.7\|1234271\|29\|NZ_CP046108\|CRISPRCasFinder	1234271-1234299	29	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	41999-42027	8	0.724
NZ_CP046108_2	2.7\|1234271\|29\|NZ_CP046108\|CRISPRCasFinder	1234271-1234299	29	MT708547	Klebsiella phage Muenster, complete genome	164107-164135	8	0.724
NZ_CP046108_2	2.7\|1234271\|29\|NZ_CP046108\|CRISPRCasFinder	1234271-1234299	29	AB897757	Klebsiella phage K64-1 DNA, complete genome	42007-42035	8	0.724
NZ_CP046108_3	3.2\|2514416\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514416-2514445	30	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	690478-690507	8	0.733
NZ_CP046108_3	3.2\|2514416\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514416-2514445	30	NZ_CP045361	Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence	103642-103671	8	0.733
NZ_CP046108_3	3.2\|2514416\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514416-2514445	30	NZ_CP045319	Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence	226475-226504	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP009119	Borreliella valaisiana Tom4006 plasmid lp54, complete sequence	48414-48443	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP028862	Borreliella garinii strain 20047 plasmid lp54, complete sequence	48678-48707	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP017218	Borreliella burgdorferi strain B331 plasmid B331_lp54, complete sequence	48096-48125	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP009214	Borreliella afzelii Tom3107 plasmid lp54, complete sequence	49892-49921	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_017804	Borreliella garinii BgVir plasmid lp54, complete sequence	49679-49708	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP009059	Borreliella afzelii K78 plasmid lp54, complete sequence	8378-8407	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP018745	Borreliella garinii strain CIP 103362 isolate 20047 plasmid p_lp54_linear	8781-8810	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_015919	Borreliella bissettii DN127 plasmid lp54, complete sequence	5660-5689	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP031397	Borreliella burgdorferi strain MM1 plasmid plsm_lp54, complete sequence	5776-5805	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	CP009912	Borreliella chilensis strain VA1 plasmid lp54, complete sequence	7485-7514	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP019854	Borreliella burgdorferi plasmid lp54, complete sequence	5632-5661	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP019765	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence	5632-5661	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP015809	Borrelia mayonii strain MN14-1539 plasmid lp54	6195-6224	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_011784	Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence	5588-5617	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_013130	Borreliella burgdorferi N40 plasmid N40_lp54, complete sequence	5626-5655	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NZ_CP015795	Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence	6195-6224	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_013128	Borrelia burgdorferi 297 plasmid 297_lp54, complete sequence	3341-3370	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_013129	Borreliella burgdorferi JD1 plasmid JD1_lp54, complete sequence	5617-5646	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_006129	Borreliella bavariensis PBi plasmid lp54, complete sequence	5944-5973	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_017241	Borreliella afzelii PKo plasmid lp54, complete sequence	8242-8271	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_001857	Borreliella burgdorferi B31 plasmid lp54, complete sequence	5632-5661	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	LN681539	Clostridium phage phiCD505, complete genome	16679-16708	8	0.733
NZ_CP046108_3	3.11\|2515010\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2515010-2515039	30	NC_048642	Clostridium phage CDKM9, complete genome	16617-16646	8	0.733
NZ_CP046108_3	3.2\|2514416\|30\|NZ_CP046108\|CRISPRCasFinder,CRT	2514416-2514445	30	NZ_CP042333	Bosea sp. F3-2 plasmid pB32-2, complete sequence	30149-30178	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KY463452	Escherichia coli strain WCHEC050622 plasmid pMCR_WCHEC1622, complete sequence	22118-22147	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KP324830	Escherichia coli isolate FP671 plasmid pHNFP671, complete sequence	40200-40229	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP035638	Enterobacter cloacae strain EN3600 plasmid unnamed6, complete sequence	49341-49370	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	MN542377	Klebsiella pneumoniae subsp. pneumoniae strain 494 plasmid pKPC2_sg1, complete sequence	66385-66414	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	MN542378	Klebsiella pneumoniae subsp. pneumoniae strain 607 plasmid pKPC2_sg2, complete sequence	66385-66414	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	LC549805	Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence	44992-45021	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP033354	Salmonella enterica subsp. enterica strain CFSA664 plasmid pCFSA664-2, complete sequence	3011-3040	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP032987	Escherichia coli strain BE2-5 plasmid pMCR_BE2-5, complete sequence	41525-41554	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP025711	Escherichia coli strain YDC107 plasmid pYDC107_41, complete sequence	2179-2208	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP035195	Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence	20709-20738	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP045957	Salmonella enterica subsp. enterica serovar Enteritidis strain AUSMDU00010527 plasmid pAUSMDU00010527, complete sequence	2179-2208	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MF978389	Escherichia coli strain GDT6F36 plasmid pHNGDF36-1, complete sequence	8704-8733	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MF990207	Escherichia coli strain GDP6F1 plasmid pHNGDF1-1, complete sequence	3788-3817	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MF678351	Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence	31703-31732	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MF136778	Escherichia coli strain HKSHmcr1_P2_EC plasmid pHKSHmcr1_P2_p1, complete sequence	16403-16432	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KX580713	Escherichia coli strain ZJ623 plasmid unnamed, complete sequence	5629-5658	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KY352406	Salmonella enterica subsp. enterica serovar Typhimurium strain YL14P053 plasmid pMCR16_P053, complete sequence	31390-31419	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NC_022650	Escherichia coli JJ1886 plasmid pJJ1886_4, complete sequence	17317-17346	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KX377410	Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence	35827-35856	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_KP008371	Klebsiella pneumoniae strain 565 plasmid PKPCAPSS, complete sequence	67651-67680	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP042602	Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence	3548-3577	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP030221	Salmonella enterica strain SA20021456 plasmid pSA20021456.2, complete sequence	16247-16276	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP024128	Escherichia coli strain 14EC001 plasmid p14EC001a, complete sequence	45705-45734	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP044383	Klebsiella pneumoniae strain 2018S07-013 plasmid p2018S07-013-3_MCR3, complete sequence	47828-47857	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP051225	Escherichia coli strain SCZE5 plasmid pSCZE3	4106-4135	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NC_023907	Escherichia coli strain HS102707 plasmid pHS102707, complete sequence	7091-7120	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_AP021897	Escherichia coli strain 2018-02-2CC plasmid p2018_02_02CC, complete sequence	19697-19726	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MH043623	Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence	29280-29309	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MH043626	Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence	29086-29115	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MG552133	Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence	27121-27150	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MF489760	Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence	29088-29117	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_MH043625	Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence	29097-29126	9	0.7
NZ_CP046108_3	3.8\|2514812\|30\|NZ_CP046108\|CRISPRCasFinder,CRT,PILER-CR	2514812-2514841	30	NZ_CP027203	Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence	16830-16859	9	0.7

1. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttctcc	Protospacer
******************************

2. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttctcc	Protospacer
******************************

3. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttctcc	Protospacer
******************************

4. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP041739 (Enterococcus faecalis EnGen0107 strain B594 plasmid p1, complete sequence) position: , mismatch: 0, identity: 1.0

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttctcc	Protospacer
*****************************

5. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttctcc	Protospacer
*****************************

6. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttctcc	Protospacer
*****************************

7. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MK721190 (Enterococcus phage vB_EfaS_Ef6.4, complete genome) position: , mismatch: 0, identity: 1.0

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
gaaacttgatgtgctacacctttagcccca	Protospacer
******************************

8. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to GQ478085 (Enterococcus phage phiFL2B, complete genome) position: , mismatch: 0, identity: 1.0

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagcgttgtgtaatgtgtccatttcttt	Protospacer
******************************

9. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_013643 (Enterococcus phage phiFL2A, complete genome) position: , mismatch: 0, identity: 1.0

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagcgttgtgtaatgtgtccatttcttt	Protospacer
******************************

10. spacer 3.7|2514746|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to GQ452243 (Enterococcus phage phiEf11, complete genome) position: , mismatch: 0, identity: 1.0

caacaatttccaccatacgttttttctcgc	CRISPR spacer
caacaatttccaccatacgttttttctcgc	Protospacer
******************************

11. spacer 3.7|2514746|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_028671 (Enterococcus phage vB_EfaS_IME197, complete genome) position: , mismatch: 0, identity: 1.0

caacaatttccaccatacgttttttctcgc	CRISPR spacer
caacaatttccaccatacgttttttctcgc	Protospacer
******************************

12. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP022484 (Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence) position: , mismatch: 1, identity: 0.967

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttcttc	Protospacer
****************************.*

13. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.967

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttcttc	Protospacer
****************************.*

14. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 1, identity: 0.967

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttcttc	Protospacer
****************************.*

15. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 1, identity: 0.967

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgtcaaaacagcagctacatttcttc	Protospacer
****************************.*

16. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP022484 (Enterococcus faecalis ARO1/DG plasmid pARO1.1, complete sequence) position: , mismatch: 1, identity: 0.966

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttcttc	Protospacer
***************************.*

17. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.966

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttcttc	Protospacer
***************************.*

18. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP042217 (Enterococcus faecalis strain L8 plasmid pL8, complete sequence) position: , mismatch: 1, identity: 0.966

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttcttc	Protospacer
***************************.*

19. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 1, identity: 0.966

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgtcaaaacagcagctacatttcttc	Protospacer
***************************.*

20. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MK721187 (Enterococcus phage vB_EfaS_Ef6.1, complete genome) position: , mismatch: 1, identity: 0.967

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
gaaacttgatatgctacacctttagcccca	Protospacer
**********.*******************

21. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to GQ478087 (Enterococcus phage phiFL3B, complete genome) position: , mismatch: 1, identity: 0.967

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtccatttcttt	Protospacer
*****.************************

22. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_013648 (Enterococcus phage phiFL3A, complete genome) position: , mismatch: 1, identity: 0.967

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtccatttcttt	Protospacer
*****.************************

23. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to GQ452243 (Enterococcus phage phiEf11, complete genome) position: , mismatch: 1, identity: 0.967

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtccatttcttt	Protospacer
*****.************************

24. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_028671 (Enterococcus phage vB_EfaS_IME197, complete genome) position: , mismatch: 1, identity: 0.967

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtccatttcttt	Protospacer
*****.************************

25. spacer 3.7|2514746|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to KJ608188 (Enterococcus phage EFC-1, complete genome) position: , mismatch: 1, identity: 0.967

caacaatttccaccatacgttttttctcgc	CRISPR spacer
ctacaatttccaccatacgttttttctcgc	Protospacer
* ****************************

26. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MT119359 (Enterococcus phage heks, complete genome) position: , mismatch: 2, identity: 0.933

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
gaaatttgatatgctacacctttagcccca	Protospacer
****.*****.*******************

27. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MK125140 (Enterococcus phage Nonaheksakonda, complete genome) position: , mismatch: 2, identity: 0.933

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
gaaatttgatatgctacacctttagcccca	Protospacer
****.*****.*******************

28. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_042023 (Enterococcus phage phiSHEF5, complete genome) position: , mismatch: 2, identity: 0.933

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
gaaatttgatgtgctacacctttaacccca	Protospacer
****.*******************.*****

29. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to GQ478082 (Enterococcus phage phiFL1B, complete genome) position: , mismatch: 2, identity: 0.933

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtctatttcttt	Protospacer
*****.***************.********

30. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to GQ478083 (Enterococcus phage phiFL1C, complete genome) position: , mismatch: 2, identity: 0.933

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtctatttcttt	Protospacer
*****.***************.********

31. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_013646 (Enterococcus phage phiFL1A, complete genome) position: , mismatch: 2, identity: 0.933

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
gaaagtgttgtgtaatgtgtctatttcttt	Protospacer
*****.***************.********

32. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 3, identity: 0.9

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
ctaatgttaaaacagcagctacctttcttc	Protospacer
*******.************** *****.*

33. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP015884 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p1, complete sequence) position: , mismatch: 3, identity: 0.897

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
taatgttaaaacagcagctacctttcttc	Protospacer
******.************** *****.*

34. spacer 2.7|1234271|29|NZ_CP046108|CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 5, identity: 0.828

caagaaattgcattaagttcaaaaaattt	CRISPR spacer
aatgtaattgcattaagagcaaaaaattt	Protospacer
 * * ************  **********

35. spacer 2.8|1234270|30|NZ_CP046108|CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 5, identity: 0.833

tcaagaaattgcattaagttcaaaaaattt	CRISPR spacer
taatgtaattgcattaagagcaaaaaattt	Protospacer
* * * ************  **********

36. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MH375074 (Enterococcus phage LY0323, complete genome) position: , mismatch: 5, identity: 0.833

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
tccattttatgtgctacacctttagcccca	Protospacer
   *.** **********************

37. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MK982307 (Enterococcus phage MSF2, complete genome) position: , mismatch: 5, identity: 0.833

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
tccattttatgtgctacacctttagcccca	Protospacer
   *.** **********************

38. spacer 3.3|2514482|30|NZ_CP046108|CRISPRCasFinder,CRT matches to KX284704 (Enterococcus phage SANTOR1, complete genome) position: , mismatch: 5, identity: 0.833

gaaacttgatgtgctacacctttagcccca	CRISPR spacer
tccattttatgtgctacacctttagcccca	Protospacer
   *.** **********************

39. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP023544 (Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence) position: , mismatch: 6, identity: 0.793

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
aagcatcaaaacagcagctacacttttcc	Protospacer
 *...*****************.**.***

40. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP017872 (Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence) position: , mismatch: 6, identity: 0.793

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
aagcatcaaaacagcagctacacttttcc	Protospacer
 *...*****************.**.***

41. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NC_022355 (Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence) position: , mismatch: 6, identity: 0.793

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
aagcatcaaaacagcagctacacttttcc	Protospacer
 *...*****************.**.***

42. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP045793 (Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence) position: , mismatch: 6, identity: 0.793

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
aagcatcaaaacagcagctacacttttcc	Protospacer
 *...*****************.**.***

43. spacer 2.5|1234139|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP023546 (Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence) position: , mismatch: 6, identity: 0.793

taatgtcaaaacagcagctacatttctcc	CRISPR spacer
aagcatcaaaacagcagctacacttttcc	Protospacer
 *...*****************.**.***

44. spacer 2.8|1234270|30|NZ_CP046108|CRT matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 6, identity: 0.8

tcaagaa--attgcattaagttcaaaaaattt	CRISPR spacer
--aacgattatggcattacgttcaaaaaattt	Protospacer
  ** .*  ** ****** *************

45. spacer 2.8|1234270|30|NZ_CP046108|CRT matches to MT708547 (Klebsiella phage Muenster, complete genome) position: , mismatch: 6, identity: 0.8

tcaagaa--attgcattaagttcaaaaaattt	CRISPR spacer
--aacgattatggcattacgttcaaaaaattt	Protospacer
  ** .*  ** ****** *************

46. spacer 2.8|1234270|30|NZ_CP046108|CRT matches to AB897757 (Klebsiella phage K64-1 DNA, complete genome) position: , mismatch: 6, identity: 0.8

tcaagaa--attgcattaagttcaaaaaattt	CRISPR spacer
--aacgattatggcattacgttcaaaaaattt	Protospacer
  ** .*  ** ****** *************

47. spacer 3.1|2514350|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MK867354 (Synechococcus phage S-SCSM1, complete genome) position: , mismatch: 6, identity: 0.8

atatgtaaatcataatgagcatttacattg	CRISPR spacer
atatggaaatcataatgaggattttccatc	Protospacer
***** ************* **** *  *

48. spacer 3.6|2514680|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_KJ776578 (Clostridium botulinum strain CDC3875 plasmid pCDC3875, complete sequence) position: , mismatch: 6, identity: 0.8

atttcaccttctgttttagaagctgcttta--	CRISPR spacer
atttcaccttgtgttttagaaa--acttcatt	Protospacer
********** **********.  .***.*

49. spacer 3.6|2514680|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_KJ776580 (Clostridium botulinum strain CDC5900 plasmid pCDC5900, complete sequence) position: , mismatch: 6, identity: 0.8

atttcaccttctgttttagaagctgcttta--	CRISPR spacer
atttcaccttgtgttttagaaa--acttcatt	Protospacer
********** **********.  .***.*

50. spacer 2.1|1234072|30|NZ_CP046108|PILER-CR,CRT matches to NC_019534 (Bacteroides fragilis plasmid pBFUK1, complete sequence) position: , mismatch: 7, identity: 0.767

cacttcccaaatagaaaggacgatgaaaca	CRISPR spacer
ccacgccaaaaaagaaaggacgatgaaacg	Protospacer
*  . ** *** *****************.

51. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP023544 (Campylobacter jejuni strain CFSAN032806 plasmid pCFSAN032806, complete sequence) position: , mismatch: 7, identity: 0.767

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
aaagcatcaaaacagcagctacacttttcc	Protospacer
  *...*****************.**.***

52. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP017872 (Campylobacter coli strain BP3183 plasmid pCCDM183, complete sequence) position: , mismatch: 7, identity: 0.767

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
aaagcatcaaaacagcagctacacttttcc	Protospacer
  *...*****************.**.***

53. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NC_022355 (Campylobacter coli CVM N29710 plasmid pN29710-1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
aaagcatcaaaacagcagctacacttttcc	Protospacer
  *...*****************.**.***

54. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP045793 (Campylobacter coli strain CFSAN032805 plasmid p1CFSAN032805, complete sequence) position: , mismatch: 7, identity: 0.767

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
aaagcatcaaaacagcagctacacttttcc	Protospacer
  *...*****************.**.***

55. spacer 2.2|1234138|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP023546 (Campylobacter coli strain CFSAN032805 plasmid pCFSAN032805_1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaatgtcaaaacagcagctacatttctcc	CRISPR spacer
aaagcatcaaaacagcagctacacttttcc	Protospacer
  *...*****************.**.***

56. spacer 2.4|1234073|29|NZ_CP046108|CRISPRCasFinder matches to NC_019534 (Bacteroides fragilis plasmid pBFUK1, complete sequence) position: , mismatch: 7, identity: 0.759

acttcccaaatagaaaggacgatgaaaca	CRISPR spacer
cacgccaaaaaagaaaggacgatgaaacg	Protospacer
  . ** *** *****************.

57. spacer 2.4|1234073|29|NZ_CP046108|CRISPRCasFinder matches to NZ_CP034946 (Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

acttcccaaatagaaaggacgatgaaaca	CRISPR spacer
tgtaaaaaaatagaaaggacgataaaaca	Protospacer
  *    ****************.*****

58. spacer 2.4|1234073|29|NZ_CP046108|CRISPRCasFinder matches to MT188223 (Acinetobacter phage vB_AbaM_D22, complete genome) position: , mismatch: 7, identity: 0.759

acttcccaaatagaaaggacgatgaaaca	CRISPR spacer
aaaacacaaatagaaaggccgatgaaagc	Protospacer
*   * ************ ********

59. spacer 2.6|1234205|29|NZ_CP046108|CRISPRCasFinder matches to NC_009453 (Arthrobacter sp. Rue61a plasmid pAL1, complete sequence) position: , mismatch: 7, identity: 0.759

gggttgactaaagagccgtcaaaagtttt	CRISPR spacer
cggttgacttcagagccgtcaaaaaatgc	Protospacer
 ********  *************. * .

60. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to MH179477 (Aeromonas phage 60AhydR15PP, complete genome) position: , mismatch: 7, identity: 0.767

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
tggagcgttgtgaaatttgtccatttcata	Protospacer
 ..********* *** ********** *

61. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_014635 (Aeromonas phage phiAS4, complete genome) position: , mismatch: 7, identity: 0.767

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
tggagcgttgtgaaatttgtccatttcata	Protospacer
 ..********* *** ********** *

62. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NC_020879 (Aeromonas phage Aes012, complete genome) position: , mismatch: 7, identity: 0.767

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
tggagcgttgtgaaatttgtccatttcata	Protospacer
 ..********* *** ********** *

63. spacer 3.4|2514548|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_CP025802 (Yersinia ruckeri strain SC09 plasmid pLT, complete sequence) position: , mismatch: 7, identity: 0.767

gaaagcgttgtgtaatgtgtccatttcttt	CRISPR spacer
tagctctttgcgtaacgtgtccatttcttt	Protospacer
 *.  * ***.****.**************

64. spacer 3.6|2514680|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_CP014218 (Clostridium botulinum strain B515 plasmid pRSJ21_3, complete sequence) position: , mismatch: 7, identity: 0.767

atttcaccttctgttttagaagctgcttta	CRISPR spacer
cttgatacttctcttttataagctgcttta	Protospacer
 **    ***** ***** ***********

65. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to GQ478087 (Enterococcus phage phiFL3B, complete genome) position: , mismatch: 7, identity: 0.767

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
agaaatctatactaatatttttaagacaat	Protospacer
***** ******* **********..  .*

66. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_013648 (Enterococcus phage phiFL3A, complete genome) position: , mismatch: 7, identity: 0.767

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
agaaatctatactaatatttttaagacaat	Protospacer
***** ******* **********..  .*

67. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP017969 (Fusobacterium varium strain Fv113-g1 plasmid pFV113-g1-1, complete sequence) position: , mismatch: 7, identity: 0.767

agaaaactatactcatatttttaa-aggtgt	CRISPR spacer
tgataactataatcatatttttaataaata-	Protospacer
 ** ******* ************ *..*.

68. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to MH319764 (Marine virus AG-345-P14 Ga0172274_11 genomic sequence) position: , mismatch: 7, identity: 0.767

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
ataaaaatatactcatatttataaaaaagg	Protospacer
* **** ************* ****.. *

69. spacer 3.12|2515076|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to MN694628 (Marine virus AFVG_250M527, complete genome) position: , mismatch: 7, identity: 0.767

gataacttagaaaagatgcaggatgttttt	CRISPR spacer
aacaacttagaaaagatgaagaatgttcag	Protospacer
.*.*************** **.*****.

70. spacer 3.12|2515076|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to MN856107 (Bacteriophage sp. isolate 216, complete genome) position: , mismatch: 7, identity: 0.767

gataacttagaaaagatgcaggatgttttt----	CRISPR spacer
gatatcttagaaaagatgca----gttatccaga	Protospacer
**** ***************    *** *.

71. spacer 2.1|1234072|30|NZ_CP046108|PILER-CR,CRT matches to NZ_CP034946 (Enterococcus faecium strain NM213 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

cacttcccaaatagaaaggacgatgaaaca	CRISPR spacer
atgtaaaaaaatagaaaggacgataaaaca	Protospacer
   *    ****************.*****

72. spacer 2.1|1234072|30|NZ_CP046108|PILER-CR,CRT matches to MT188223 (Acinetobacter phage vB_AbaM_D22, complete genome) position: , mismatch: 8, identity: 0.733

cacttcccaaatagaaaggacgatgaaaca	CRISPR spacer
taaaacacaaatagaaaggccgatgaaagc	Protospacer
.*   * ************ ********

73. spacer 2.3|1234204|30|NZ_CP046108|PILER-CR,CRT matches to NC_009453 (Arthrobacter sp. Rue61a plasmid pAL1, complete sequence) position: , mismatch: 8, identity: 0.733

tgggttgactaaagagccgtcaaaagtttt	CRISPR spacer
acggttgacttcagagccgtcaaaaaatgc	Protospacer
  ********  *************. * .

74. spacer 2.7|1234271|29|NZ_CP046108|CRISPRCasFinder matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 8, identity: 0.724

caagaaattgcattaagttcaaaaaattt	CRISPR spacer
acgattatggcattacgttcaaaaaattt	Protospacer
  ..  ** ****** *************

75. spacer 2.7|1234271|29|NZ_CP046108|CRISPRCasFinder matches to MT708547 (Klebsiella phage Muenster, complete genome) position: , mismatch: 8, identity: 0.724

caagaaattgcattaagttcaaaaaattt	CRISPR spacer
acgattatggcattacgttcaaaaaattt	Protospacer
  ..  ** ****** *************

76. spacer 2.7|1234271|29|NZ_CP046108|CRISPRCasFinder matches to AB897757 (Klebsiella phage K64-1 DNA, complete genome) position: , mismatch: 8, identity: 0.724

caagaaattgcattaagttcaaaaaattt	CRISPR spacer
acgattatggcattacgttcaaaaaattt	Protospacer
  ..  ** ****** *************

77. spacer 3.2|2514416|30|NZ_CP046108|CRISPRCasFinder,CRT matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
ggagcgatggagcacgatggtctgcaccgc	Protospacer
 .************ * ********  .*

78. spacer 3.2|2514416|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_CP045361 (Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
taagcgatggcgcaggttggtcaggccgca	Protospacer
.********* *********** * .   *

79. spacer 3.2|2514416|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_CP045319 (Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence) position: , mismatch: 8, identity: 0.733

caagcgatggagcaggttggtctgctatga	CRISPR spacer
taagcgatggcgcaggttggtcaggccgca	Protospacer
.********* *********** * .   *

80. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009119 (Borreliella valaisiana Tom4006 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

81. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028862 (Borreliella garinii strain 20047 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

82. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017218 (Borreliella burgdorferi strain B331 plasmid B331_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

83. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009214 (Borreliella afzelii Tom3107 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

84. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_017804 (Borreliella garinii BgVir plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

85. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009059 (Borreliella afzelii K78 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

86. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018745 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid p_lp54_linear) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

87. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_015919 (Borreliella bissettii DN127 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

88. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031397 (Borreliella burgdorferi strain MM1 plasmid plsm_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

89. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to CP009912 (Borreliella chilensis strain VA1 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

90. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019854 (Borreliella burgdorferi plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

91. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019765 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

92. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015809 (Borrelia mayonii strain MN14-1539 plasmid lp54) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

93. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_011784 (Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

94. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_013130 (Borreliella burgdorferi N40 plasmid N40_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

95. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015795 (Borrelia mayonii strain MN14-1420 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

96. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_013128 (Borrelia burgdorferi 297 plasmid 297_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

97. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_013129 (Borreliella burgdorferi JD1 plasmid JD1_lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

98. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_006129 (Borreliella bavariensis PBi plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

99. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_017241 (Borreliella afzelii PKo plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

100. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_001857 (Borreliella burgdorferi B31 plasmid lp54, complete sequence) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
caaaaattatactcatattttaaaatccat	Protospacer
 .****.************** ***  ..*

101. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to LN681539 (Clostridium phage phiCD505, complete genome) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
ttaagattatactcatatttttaaatcttc	Protospacer
  **.*.******************  * .

102. spacer 3.11|2515010|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_048642 (Clostridium phage CDKM9, complete genome) position: , mismatch: 8, identity: 0.733

agaaaactatactcatatttttaaaggtgt	CRISPR spacer
ttaagattatactcatatttttaaatcttc	Protospacer
  **.*.******************  * .

103. spacer 3.2|2514416|30|NZ_CP046108|CRISPRCasFinder,CRT matches to NZ_CP042333 (Bosea sp. F3-2 plasmid pB32-2, complete sequence) position: , mismatch: 9, identity: 0.7

caagcgatggagcaggttggtctgctatga	CRISPR spacer
ggggcgttggagcaggttgggctgctggcc	Protospacer
 ..*** ************* *****.

104. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY463452 (Escherichia coli strain WCHEC050622 plasmid pMCR_WCHEC1622, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

105. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KP324830 (Escherichia coli isolate FP671 plasmid pHNFP671, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

106. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035638 (Enterobacter cloacae strain EN3600 plasmid unnamed6, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

107. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to MN542377 (Klebsiella pneumoniae subsp. pneumoniae strain 494 plasmid pKPC2_sg1, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

108. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to MN542378 (Klebsiella pneumoniae subsp. pneumoniae strain 607 plasmid pKPC2_sg2, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

109. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to LC549805 (Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

110. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033354 (Salmonella enterica subsp. enterica strain CFSA664 plasmid pCFSA664-2, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

111. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032987 (Escherichia coli strain BE2-5 plasmid pMCR_BE2-5, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

112. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025711 (Escherichia coli strain YDC107 plasmid pYDC107_41, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

113. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035195 (Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

114. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045957 (Salmonella enterica subsp. enterica serovar Enteritidis strain AUSMDU00010527 plasmid pAUSMDU00010527, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

115. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF978389 (Escherichia coli strain GDT6F36 plasmid pHNGDF36-1, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

116. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF990207 (Escherichia coli strain GDP6F1 plasmid pHNGDF1-1, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

117. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF678351 (Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

118. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF136778 (Escherichia coli strain HKSHmcr1_P2_EC plasmid pHKSHmcr1_P2_p1, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

119. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX580713 (Escherichia coli strain ZJ623 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

120. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY352406 (Salmonella enterica subsp. enterica serovar Typhimurium strain YL14P053 plasmid pMCR16_P053, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

121. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_022650 (Escherichia coli JJ1886 plasmid pJJ1886_4, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

122. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX377410 (Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

123. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KP008371 (Klebsiella pneumoniae strain 565 plasmid PKPCAPSS, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

124. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042602 (Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

125. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030221 (Salmonella enterica strain SA20021456 plasmid pSA20021456.2, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

126. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024128 (Escherichia coli strain 14EC001 plasmid p14EC001a, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

127. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044383 (Klebsiella pneumoniae strain 2018S07-013 plasmid p2018S07-013-3_MCR3, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

128. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051225 (Escherichia coli strain SCZE5 plasmid pSCZE3) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

129. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NC_023907 (Escherichia coli strain HS102707 plasmid pHS102707, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

130. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP021897 (Escherichia coli strain 2018-02-2CC plasmid p2018_02_02CC, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

131. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH043623 (Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

132. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH043626 (Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

133. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG552133 (Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

134. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MF489760 (Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

135. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH043625 (Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

136. spacer 3.8|2514812|30|NZ_CP046108|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027203 (Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence) position: , mismatch: 9, identity: 0.7

gcatatcaagcgcactacttaaatgaaaac	CRISPR spacer
ttttatccagcgcactacttaaatattggc	Protospacer
 . **** ****************.  ..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

723377 : 733116

Streptococcus_phage(57.14%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002356366.1\|723377_724016_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8
WP_002356367.1\|724035_724365_+	cyclic-di-AMP receptor	NA	NA	NA	NA
WP_002389791.1\|724366_725317_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356371.1\|725432_726272_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002356372.1\|726264_726612_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356373.1\|726723_727596_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	6.2e-81	57.6
WP_002356375.1\|727610_728273_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002356377.1\|728256_729015_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002362328.1\|729140_730259_+	DNA polymerase IV	NA	NA	NA	NA
WP_002356379.1\|730303_730900_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002385686.1\|730932_733116_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8

DBSCAN-SWA_2

1226491 : 1292097

Enterococcus_phage(34.38%)

tail,transposase,portal,capsid,integrase,holin,terminase,head,tRNA

attL 1252242:1252257|attR 1258627:1258642

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002362075.1\|1226491_1227616_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_002356963.1\|1229037_1229553_-	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_002356965.1\|1229685_1230255_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002356966.1\|1230352_1230718_+	DUF1033 family protein	NA	NA	NA	NA
WP_002402469.1\|1230680_1232930_+	DNA topoisomerase III	NA	NA	NA	NA
WP_002372057.1\|1233014_1233878_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_002356974.1\|1234741_1236160_+	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_002356976.1\|1236156_1237170_+	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_002369918.1\|1237174_1238908_+	thiol reductant ABC exporter subunit CydD	A0A2H4UU96	Bodo_saltans_virus	8.5e-13	23.4
WP_002369917.1\|1238904_1240671_+	thiol reductant ABC exporter subunit CydC	W8CYL7	Bacillus_phage	4.1e-23	25.8
WP_002378476.1\|1240750_1241731_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002360016.1\|1241852_1242758_+	prenyltransferase	NA	NA	NA	NA
WP_002360017.1\|1242786_1243998_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002364367.1\|1244311_1246735_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.2e-83	48.0
WP_002356983.1\|1246864_1247566_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002372053.1\|1247683_1248433_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.1e-33	36.5
WP_002391458.1\|1248422_1250252_+	ABC transporter permease	NA	NA	NA	NA
WP_002356987.1\|1250377_1251451_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_002360022.1\|1251740_1253069_+	amino acid permease	NA	NA	NA	NA
1252242:1252257	attL	NA	NA	NA	NA
WP_002369168.1\|1253310_1254279_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_002369171.1\|1254235_1255282_+	type II secretion system F family protein	NA	NA	NA	NA
WP_002356991.1\|1255281_1255557_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_016617790.1\|1255553_1255997_+	hypothetical protein	NA	NA	NA	NA
WP_002388210.1\|1256024_1257173_-\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	2.3e-38	30.7
WP_002388208.1\|1257272_1258001_-	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	4.9e-23	48.9
WP_002388207.1\|1258058_1258403_-	ImmA/IrrE family metallo-endopeptidase	D2IZV8	Enterococcus_phage	4.7e-40	70.2
WP_002388206.1\|1258421_1258757_-	helix-turn-helix transcriptional regulator	D2IZV9	Enterococcus_phage	2.8e-29	59.5
1258627:1258642	attR	NA	NA	NA	NA
WP_002388205.1\|1259048_1259231_+	hypothetical protein	NA	NA	NA	NA
WP_010712611.1\|1259243_1259441_+	hypothetical protein	NA	NA	NA	NA
WP_002381719.1\|1260037_1260349_+	hypothetical protein	NA	NA	NA	NA
WP_002357000.1\|1260371_1261094_+	phage regulatory protein	D2IYT0	Enterococcus_phage	5.6e-43	46.5
WP_002357001.1\|1261119_1261308_-	YegP family protein	NA	NA	NA	NA
WP_002357002.1\|1261362_1261572_+	hypothetical protein	D2IZ57	Enterococcus_phage	8.8e-18	72.6
WP_002357003.1\|1261608_1261947_+	hypothetical protein	NA	NA	NA	NA
WP_002357006.1\|1262231_1262786_-	hypothetical protein	NA	NA	NA	NA
WP_002357007.1\|1263005_1263323_+	hypothetical protein	NA	NA	NA	NA
WP_002385820.1\|1263315_1264050_+	ERF family protein	A0A2H4JA34	uncultured_Caudovirales_phage	1.4e-20	31.6
WP_002357009.1\|1264054_1264696_+	hypothetical protein	U5U4M2	Lactobacillus_phage	3.1e-29	35.5
WP_002357010.1\|1264700_1264901_+	hypothetical protein	NA	NA	NA	NA
WP_002364343.1\|1264900_1265758_+	helix-turn-helix domain-containing protein	A0A0P0ICZ8	Lactobacillus_phage	1.1e-24	36.1
WP_024797260.1\|1265754_1266162_+	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	2.0e-58	85.0
WP_002357018.1\|1267068_1267485_+	autolysin	D2IZ17	Enterococcus_phage	1.4e-67	99.3
WP_002378460.1\|1268199_1269108_+	hypothetical protein	NA	NA	NA	NA
WP_002378459.1\|1269137_1269587_+	hypothetical protein	NA	NA	NA	NA
WP_002364295.1\|1270319_1270754_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.8e-44	64.5
WP_002369892.1\|1270734_1272018_+\|terminase	PBSX family phage terminase large subunit	Q9AZ91	Lactobacillus_prophage	6.0e-157	65.5
WP_010785049.1\|1272017_1273502_+\|portal	phage portal protein	A0A097QPZ5	Enterococcus_phage	2.1e-137	98.0
WP_010785048.1\|1273494_1274421_+\|capsid	minor capsid protein	A0A097QPZ9	Enterococcus_phage	2.0e-130	98.0
WP_002378456.1\|1274525_1275179_+	hypothetical protein	NA	NA	NA	NA
WP_002363368.1\|1275192_1276089_+	hypothetical protein	U3PDP8	Lactobacillus_phage	3.3e-69	49.8
WP_002363369.1\|1276159_1276492_+\|head,tail	phage head-tail connector protein	A0A1W6JNH7	Staphylococcus_phage	2.7e-08	38.5
WP_002378454.1\|1276488_1276764_+	hypothetical protein	NA	NA	NA	NA
WP_002363372.1\|1276760_1277099_+	HK97 gp10 family phage protein	A0A1L2K255	Streptococcus_phage	1.8e-12	38.7
WP_002363373.1\|1277095_1277488_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_002364302.1\|1277506_1278112_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_010785047.1\|1278114_1278423_+	hypothetical protein	L0P8M2	Lactobacillus_phage	2.7e-07	77.1
WP_002409775.1\|1278485_1278884_+	hypothetical protein	NA	NA	NA	NA
WP_002364305.1\|1278952_1279258_+	hypothetical protein	NA	NA	NA	NA
WP_010785046.1\|1279244_1283699_+\|tail	phage tail tape measure protein	M1PKM6	Streptococcus_phage	4.9e-89	48.7
WP_010785045.1\|1283695_1284418_+	hypothetical protein	C5IUK4	Streptococcus_phage	6.1e-42	38.8
WP_010712603.1\|1284417_1285863_+\|tail	phage tail protein	A0A1X9IGI5	Lactococcus_phage	2.0e-76	39.0
WP_025193093.1\|1285868_1286609_+	hypothetical protein	A0A1X9IGH6	Lactococcus_phage	8.0e-21	30.0
WP_002363384.1\|1286625_1287078_+	hypothetical protein	C0LZY6	Enterococcus_phage	3.3e-17	40.3
WP_002363385.1\|1287096_1287492_+	hypothetical protein	NA	NA	NA	NA
WP_002368228.1\|1287493_1287616_+	XkdX family protein	NA	NA	NA	NA
WP_002378446.1\|1287626_1288007_+\|holin	phage holin family protein	A0A097QQ04	Enterococcus_phage	1.1e-61	100.0
WP_002346915.1\|1288143_1289394_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
WP_002381740.1\|1289790_1291050_+	LysM peptidoglycan-binding domain-containing protein	C9E2L1	Enterococcus_phage	3.3e-208	89.2
WP_002357053.1\|1291896_1292097_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.6e-24	80.3

DBSCAN-SWA_3

1878463 : 1896234

Enterococcus_phage(46.15%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002398986.1\|1878463_1879588_-	SH3 domain-containing protein	A0A139ZVY1	Enterococcus_phage	6.6e-75	43.8
WP_002357842.1\|1879706_1880102_-\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_002412049.1\|1880125_1881895_-	hypothetical protein	A0A097BYA8	Enterococcus_phage	2.3e-143	64.1
WP_002365554.1\|1881927_1883385_-\|tail	phage tail protein	C9E2K6	Enterococcus_phage	6.6e-176	48.0
WP_002365553.1\|1883397_1884324_-\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	9.0e-147	78.6
WP_002398985.1\|1884325_1887259_-	hypothetical protein	A0A1U9WR55	Streptococcus_virus	1.1e-09	25.0
WP_002382238.1\|1887248_1887542_-	hypothetical protein	NA	NA	NA	NA
WP_002357848.1\|1887634_1887994_-	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002365550.1\|1888026_1888539_-\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002382237.1\|1888551_1888968_-	hypothetical protein	NA	NA	NA	NA
WP_002360491.1\|1889188_1889596_-	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_025191557.1\|1889615_1890008_-	hypothetical protein	NA	NA	NA	NA
WP_002365547.1\|1890074_1890917_-	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	6.3e-30	30.7
WP_002393201.1\|1890935_1891691_-	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	8.7e-31	56.0
WP_002360496.1\|1892087_1892570_+	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
WP_002382232.1\|1892604_1893090_+	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002360497.1\|1893462_1893813_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002357859.1\|1893837_1896234_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1

DBSCAN-SWA_4

2253315 : 2261233

uncultured_Caudovirales_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355804.1\|2253315_2254491_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.5e-85	47.7
WP_002355803.1\|2254506_2255022_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	1.7e-38	48.8
WP_002364710.1\|2255039_2255534_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002355801.1\|2255599_2255959_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_002385048.1\|2256026_2256407_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_002355799.1\|2256452_2256812_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_002355798.1\|2256872_2257073_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355797.1\|2257186_2257708_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355796.1\|2258107_2259178_-	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002361357.1\|2259218_2260175_-	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	4.2e-06	23.9
WP_002355794.1\|2260174_2261233_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1

DBSCAN-SWA_5

2558241 : 2625825

Staphylococcus_phage(27.27%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002355444.1\|2558241_2559498_-\|tRNA	tyrosine--tRNA ligase	A0A1L2CUL7	Pectobacterium_phage	1.7e-79	40.3
WP_002361214.1\|2560194_2561640_-	cardiolipin synthase	NA	NA	NA	NA
WP_002355441.1\|2561805_2562288_-	VOC family protein	NA	NA	NA	NA
WP_002358626.1\|2562310_2563150_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.1e-69	48.5
WP_002361211.1\|2563613_2564222_-	response regulator transcription factor	NA	NA	NA	NA
WP_025191411.1\|2564202_2565747_-	ATP-binding protein	NA	NA	NA	NA
WP_002361207.1\|2567817_2568483_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.8e-27	32.6
WP_002401973.1\|2568507_2570415_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_002401974.1\|2570422_2571436_-	hypothetical protein	NA	NA	NA	NA
WP_002366123.1\|2571428_2571590_-	hypothetical protein	NA	NA	NA	NA
WP_002380061.1\|2572997_2573123_-	hypothetical protein	NA	NA	NA	NA
WP_002384871.1\|2573675_2574356_-	hypothetical protein	NA	NA	NA	NA
WP_002363112.1\|2575322_2575508_-	hypothetical protein	NA	NA	NA	NA
WP_002363111.1\|2576053_2576203_+	hypothetical protein	NA	NA	NA	NA
WP_002363110.1\|2576479_2577280_+	TrmB family transcriptional regulator	NA	NA	NA	NA
WP_002381227.1\|2577295_2578174_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_002363108.1\|2578186_2579167_+	ornithine cyclodeaminase family protein	NA	NA	NA	NA
WP_002363105.1\|2579688_2579907_+	hypothetical protein	NA	NA	NA	NA
WP_010774085.1\|2580296_2581256_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_002363103.1\|2581641_2582070_-	NusG domain II-containing protein	NA	NA	NA	NA
WP_002363099.1\|2584918_2585068_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_002363097.1\|2585088_2585466_-	hypothetical protein	NA	NA	NA	NA
WP_002297318.1\|2585496_2585676_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_002363096.1\|2585690_2585951_-	30S ribosomal protein S14	NA	NA	NA	NA
WP_002384861.1\|2586473_2588240_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.0e-29	28.4
WP_021732886.1\|2588199_2589954_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.3e-25	25.1
WP_002363093.1\|2590063_2590633_-	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_010706716.1\|2590650_2592066_-	energy-coupling factor ABC transporter ATP-binding protein	A0A1V0SGN0	Hokovirus	4.5e-20	26.4
WP_002358579.1\|2592076_2592745_-	cobalt transporter	NA	NA	NA	NA
WP_071623368.1\|2592875_2593460_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002297302.1\|2593788_2594022_-	iron-dependent repressor	NA	NA	NA	NA
WP_002364865.1\|2594036_2594987_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002388550.1\|2594983_2595826_-	metal ABC transporter permease	NA	NA	NA	NA
WP_002363088.1\|2595827_2596547_-	metal ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.2e-18	32.7
WP_048951781.1\|2596804_2597764_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002331389.1\|2599144_2599594_+	DIP1984 family protein	NA	NA	NA	NA
WP_002384856.1\|2599603_2599744_+	hypothetical protein	NA	NA	NA	NA
WP_002384854.1\|2600495_2601839_-	PFL family protein	NA	NA	NA	NA
WP_002355434.1\|2601853_2602120_-	ACT domain-containing protein	NA	NA	NA	NA
WP_002334632.1\|2602222_2602891_-	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_002367952.1\|2603237_2604080_+	MATE family efflux transporter	NA	NA	NA	NA
WP_002307675.1\|2604664_2604961_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002355429.1\|2604953_2605418_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002364876.1\|2607902_2608286_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002386124.1\|2608526_2609141_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002364878.1\|2609284_2609845_+	TetR/AcrR family transcriptional regulator C-terminal domain-containing protein	NA	NA	NA	NA
WP_002381218.1\|2609920_2611120_-	MFS transporter	NA	NA	NA	NA
WP_002331206.1\|2611562_2612054_-	hypothetical protein	NA	NA	NA	NA
WP_002331205.1\|2612080_2613226_-	galactonate dehydratase	Q6A202	Oenococcus_phage	1.2e-52	33.4
WP_002386123.1\|2613240_2614608_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_002331203.1\|2614632_2614911_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002326530.1\|2614929_2615388_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002331202.1\|2615399_2616020_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_002367946.1\|2616030_2618073_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002364885.1\|2618354_2619590_-\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_002367943.1\|2619586_2620171_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_010830483.1\|2620347_2623392_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.2e-17	23.2
WP_010717287.1\|2623621_2624581_+\|transposase	IS30-like element IS6770 family transposase	NA	NA	NA	NA
WP_002367939.1\|2625132_2625408_+\|transposase	transposase	A0A0N9S8A3	Staphylococcus_phage	1.1e-10	40.9
WP_002370911.1\|2625513_2625825_+\|transposase	IS3 family transposase	A0A0N9SIX5	Staphylococcus_phage	1.6e-23	65.6

DBSCAN-SWA_6

2875894 : 2893416

Streptococcus_phage(100.0%)

integrase

attL 2875444:2875458|attR 2878047:2878061

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2875444:2875458	attL	NA	NA	NA	NA
WP_001291561.1\|2875894_2877112_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|2877193_2877397_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|2877857_2878088_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
2878047:2878061	attR	NA	NA	NA	NA
WP_000804885.1\|2878084_2878507_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|2879011_2879365_+	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000691736.1\|2879709_2881629_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
WP_001814923.1\|2881644_2881761_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224318.1\|2882005_2882938_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_000769868.1\|2882934_2883936_-	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_000804748.1\|2883932_2886110_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	100.0
WP_000331160.1\|2886112_2888560_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|2888543_2889050_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|2889024_2889522_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|2889638_2889860_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_010830472.1\|2889902_2891108_-	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	3.7e-233	99.8
WP_000879507.1\|2891130_2891283_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|2891285_2892671_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|2892699_2893086_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|2893101_2893416_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP046109

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP046109_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP046109_1

426-557

Orphan

Consensus_repeat	Method
TTTCGAAAGTGGGAAAAACCAAC	CRISPRCasFinder
TTCGTTCGAAAGTGGGAAAAACCAACC	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP046109_1

>merge|NZ_CP046109|1|426-557|CRISPRCasFinder,PILER-CR
TCCCGAAAGTGGGAAAAACCAACCTTCGGATAAACATGATAAAATCGGCGTTTCTTTCGAAAGTGGGAAAAACCAACGTCCAGAAGAATCCAATAATACCAGTACTTTGTTCGAAAGTGGGAAAAACCAACC

>NZ_CP046109|1|1|426-556|CRISPRCasFinder
TCCCGAAAGTGGGAAAAACCAAC	CTTCGGATAAACATGATAAAATCGGCGTTTC
TTTCGAAAGTGGGAAAAACCAAC	GTCCAGAAGAATCCAATAATACCAGTACTTT
GTTCGAAAGTGGGAAAAACCAAC

>NZ_CP046109|1|1|429-557|PILER-CR
CGAAAGTGGGAAAAACCAACCTTCGGA	TAAACATGATAAAATCGGCGTTTCTTT
CGAAAGTGGGAAAAACCAACGTCCAGA	AGAATCCAATAATACCAGTACTTTGTT
CGAAAGTGGGAAAAACCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP046109.1\|WP_048947141.1\|15039_15396_+\|pheromone-response-system-RNA-binding-regulator-PrgU	unknown	unknown	gnl\|CDD\|286680
NZ_CP046109.1\|WP_002365954.1\|5723_6080_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046109.1\|WP_012579113.1\|11052_14979_+\|LPXTG-anchored-aggregation-substance	unknown	unknown	gnl\|CDD\|369832
NZ_CP046109.1\|WP_002360909.1\|9672_9951_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273908
NZ_CP046109.1\|WP_010715978.1\|1166_2804_+\|peptide-pheromone-binding-protein-TraC	unknown	unknown	gnl\|CDD\|173869
NZ_CP046109.1\|WP_012579112.1\|6977_9653_+\|surface-exclusion-protein-SEA1/PrgA	unknown	unknown	gnl\|CDD\|275124
NZ_CP046109.1\|WP_174776107.1\|6661_6967_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP046109.1\|WP_002366016.1\|2814_3969_+\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|224828
NZ_CP046109.1\|WP_002360910.1\|10410_10746_+\|DUF5406-domain-containing-protein	unknown	unknown	gnl\|CDD\|379975
NZ_CP046109.1\|WP_002366018.1\|4001_4955_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775

Protein	Function_ID	Function_description	E-value
NZ_CP046109.1\|WP_048947141.1\|15039_15396_+\|pheromone-response-system-RNA-binding-regulator-PrgU	gnl\|CDD\|286680	pfam09627, PrgU, PrgU-like protein. This hypothetical protein of 125 residues is expressed in bacteria but is thought to be plasmid in origin. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. It may be involved in pheromone-inducible conjugation.	8.13209e-62
NZ_CP046109.1\|WP_002360910.1\|10410_10746_+\|DUF5406-domain-containing-protein	gnl\|CDD\|379975	pfam17400, DUF5406, Family of unknown function (DUF5406). This is a family of unknown function found in Bacteria.	1.86262e-48
NZ_CP046109.1\|WP_012579113.1\|11052_14979_+\|LPXTG-anchored-aggregation-substance	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	1.09067e-72
NZ_CP046109.1\|WP_002360909.1\|9672_9951_+\|hypothetical-protein	gnl\|CDD\|273908	TIGR01981, UPF0051_protein_Rv1462/MT1509, FeS assembly protein SufD. This protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0.00296089
NZ_CP046109.1\|WP_010715978.1\|1166_2804_+\|peptide-pheromone-binding-protein-TraC	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_CP046109.1\|WP_012579112.1\|6977_9653_+\|surface-exclusion-protein-SEA1/PrgA	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	2.16407e-43
NZ_CP046109.1\|WP_002366016.1\|2814_3969_+\|TraB/GumN-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	2.7588e-92
NZ_CP046109.1\|WP_002366018.1\|4001_4955_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	1.69683e-05

>NZ_CP046109.1|WP_010715978.1|1166_2804_+|peptide-pheromone-binding-protein-TraC
MKKYKKFCFLGIGLLPLVLASCGTNTATKDSQDATEKKVEQVATLTAGTPVQSLDPATAVDQTSITLLANVMEGLYRLDEKNQPQPAIAAGQPKVSNNGKTYTIVIRDGAKWSDGTQITASDFVAAWQRVVDPKTASPNVELFSAIKNAKEIASGKQAKDTLAVKSIGEKTLEIELVEPTPYFTDLLSLTAYYPVQQKAIKEYGKDYGVSQKAIVTNGAFNLTNLEGVGTSDKWTISKNKEYWDQKDVSMDKINFQVVKEINTGINLYNDGQLDEAPLAGEYAKQYKKDKEYSTTLMANTMFLEMNQTGENKLLQNKNVRKAISYAIDRESLVKKLLDNGSVASVGVVPKEMAFNPVNKKDFANEKLVEFNKKQAEEYWDKAKKEIDLSKNTSLDLLVSDGEFEKKAGEFLQGQLQDSLEGLKVNVTPIPANVFMERLTKKDFTLSLSGWQADYADPISFLANFETNSPMNHGGYSNKNYDELLKDSSSKRWQELKKAEKLLINDMGVVPIFQVGTAKLEKSKIKNVLMHSIGAKYDYKKMRIEK
>NZ_CP046109.1|WP_002366016.1|2814_3969_+|TraB/GumN-family-protein
MELVRRVFIKDKEIILVGTAHISSESAELVKNIIEEENPDVVCLEWDQSRYDKYLNPDEWSDTDIVQVIKQKRLTVLISSVIYKLIQKHLAKINDSVAGAEFFEAVSSAEKVGAKIALVDRDSQVTFKRFWRLIPLRKKALLPYAFGSVLEGAEESEEEMLKLLNSENFEPIFEQLQEAYPELWKVLLVERDQYLAQKISDQEAGKIVVVIGQAHLRGVEKNLKSNQQINIKELETLPPKLWSTKVLESIIPLIIIGLLIYSFFLGVDVGKDQIMRWGIWNGGLSALFTLLALAHPLTIVTSLVFAPLATLLPMVSVGVFSAIVEATLRKPKVRDFQTMDEDIKSLKKIYKNRVLRVFLVFVLASLGGMIGNFVGGLEMFRHLI
>NZ_CP046109.1|WP_002366018.1|4001_4955_-|helix-turn-helix-transcriptional-regulator
MFKIGSVLKQIRQELNYHQIDLYSGIMSKSVYIKVEADSRPISVEELSKFSERLGVNFFEILNRAGMNTKSVNETGKEKLLISKIFTNPDLFDKNFQRIEPKRLTSLQYFSIYLGYISIAHHYNIEVPTFNKTITSDLKHLYDKRTTFFGIDYEIVSNLLNVLPYEEVSSIIKPMYPIVDSFGKDYDLTIQTVLKNALTISIMNRNLKEAQYYINQFEHLKTIKNISINGYYDLEINYLKQIYQFLTDKNIDSYLNAVNIINIFKIIGKEDIHRSLVEELTKISAKEKFTPPKEVTMYYENYVAIENNPIPEIKEQS
>NZ_CP046109.1|WP_002365954.1|5723_6080_+|hypothetical-protein
MSCFSVLRIEHVGYYGNRIIVFGQREKRKLPNATSKFVRKTKTYRIEGMFAVQIEKYFKGKKLCEREVGQVPLRSVYKQIKHVYDHNGVLIARRNSPSGPLKVTGRGMSKFLDYDKKS
>NZ_CP046109.1|WP_174776107.1|6661_6967_+|hypothetical-protein
MTKKEQNIWRKEMLALMNEDADWYRNEDTERFKRIQELAKKIETASARQFSSHISKERFEAYQKMGLQFKEIAEEFHITTTALQQWRKDNGYPIYNKNNKK
>NZ_CP046109.1|WP_012579112.1|6977_9653_+|surface-exclusion-protein-SEA1/PrgA
MKKFASAGLSILVATGVAGIGGNEVQAAEQAQPKTPENSSTEQPAVKGTQTTEQAITEKQQQVTEKQAIVDQKQQVADTAKKEKDTIDQSVKDQQAVVDQNKDALDQSQQAVTDQQTVVDEAKKVVDEATPSAIEKAKDQVATDTQAVDDQQKVVDQAQTDVNQQQAVVDEKAKETNAAKVQNDKDQQAVTAAKQEQAKLEELAKNAEAEKAKAEKEQAAKEAELANKQKEEAKAKDQKTKDDQAVADQQTVVTTSQEKVTDAKADTAAKQADLTAKENALKDKQAATKQAQNTLDNSKEELKGHKGINLPANFTPDYYKKLSEQEKQAMEKEALALNKVFPENQADAAKATEMIDIKNPTEKQKKQMSDYFVGLLNDVREKLGLQKLKVSSQNIKFAWDNAKYTNPNEIGHDENAINKAAKENGFKEYPGQNFYENLSGGYFQPKDGKISVLDFERAAREALVDMLFNDGRMGYGHTESLLQADKTNTAIALSEENHGFSSGKIHIIGYNQSRLVDQNTYEEGSVPVFKSKETLQKEVATNQEKLATAKQAESDAQQARSASQQALNTAKTTQATAEKELSVHKATLANLQAVATKSTTNYEEKVRQTATAEKSLQQTKDQLVTINELIQNRAAVLEKAKTKVADAQAIEQTSAKVLKEKQEAQKAEENTLNSLKEVLDLAKENLNQKQVALKTSTRSLSRLENAQPTYEKALNELNKAEASVVQAQEAYENSLKSLEELKEQQAVATLAYTQAQEDLSNAKLELQQYQGVLRDLEAQQAEQQRQEALQEQVAKEQQRLEREAKQNQTLVASATSADKTPGLQQLSFSKQKEQPKAQALTHSEPRKTKQVAKAPESLPQTGEQRSIWLTIIGLFMAVGAISFKNKRRKNN
>NZ_CP046109.1|WP_002360909.1|9672_9951_+|hypothetical-protein
MNFYEIKDPYLALIAAEDEKQCLKIYTENVSDVEEEEIFYTEMRTIDKYEALKMVAESNIEDGGKLGVEEAFKQLENLKEDGELLIIDGGLL
>NZ_CP046109.1|WP_002360910.1|10410_10746_+|DUF5406-domain-containing-protein
MKNYDPNIRWGLHTIKVSFQRGVYKGFVTFVKSGNCKGLDVLGIDEEDLYDMKFKENPINFRLLGEDDNGDEWFAMTLKNDKKDELLVEDVWEELSEYIVRIEIIDFEEEK
>NZ_CP046109.1|WP_012579113.1|11052_14979_+|LPXTG-anchored-aggregation-substance
MKQQTEVKKRFKTYKAKKRWVTAPILFIGVLGVVGLATDNVQAAELDSQPGTTTVQPDNPDLQSGKETPKTAVSEEAALQKDTTSQPTKVEEVAPENKGTEQSSATPNDTINAQQPTAEAEKSAQEQPVVSPETANEPLGQPTEVAPAENEANKSTIIPKEFETPDVDKAVDEAKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDKLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMGGKATGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITAFIGTNRVNGKDVKTRLTIKFFDASGKEVLPDKASPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAKSVTPKRQFNSPKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNINDLNLKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAKDVTASYDLHLDQNTVTAMMKTNADGSVVLAMGYKYLLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPRSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSVYLEVQRIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAFDTVDLATGVSFFDDYDETKVSPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELRVTLPTKVKANVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWSINDKLDVKHDKFSGQWSVFANSAFVLADGTKVNKGDDISKLFTMTFDKGVVKITASQAFLDAMNLKENKHVAHSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASIVPELPKTGEKQNVLLTVAGSLAALLGLAGLGFKRRKETK
>NZ_CP046109.1|WP_048947141.1|15039_15396_+|pheromone-response-system-RNA-binding-regulator-PrgU
MEAVVAEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIYVKPNLGKINVPVFFIKTPINRGVFEEIFGETLKG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	548-578	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	461-491	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33655-33685	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	449-479	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5472-5502	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43942-43972	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83451-83481	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4997-5027	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	773-803	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7642-7672	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66170-66200	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12175-12205	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60905-60935	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92753-92783	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43888-43918	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4943-4973	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5073-5103	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	602-632	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	515-545	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33709-33739	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	503-533	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	503-533	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5526-5556	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83505-83535	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9536-9566	0	1.0
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	827-857	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43945-43971	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	5000-5026	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	549-575	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	462-488	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33656-33682	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	450-476	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5473-5499	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83452-83478	0	1.0
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	774-800	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7645-7671	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66173-66199	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12178-12204	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60908-60934	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92756-92782	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43891-43917	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4946-4972	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5074-5100	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	603-629	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	516-542	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33710-33736	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	504-530	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	504-530	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5527-5553	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83506-83532	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9537-9563	0	1.0
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	828-854	0	1.0
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7696-7726	1	0.968
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12229-12259	1	0.968
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60959-60989	1	0.968
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92807-92837	1	0.968
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	748-778	1	0.968
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7699-7725	1	0.963
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66227-66253	1	0.963
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12232-12258	1	0.963
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60962-60988	1	0.963
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92810-92836	1	0.963
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	450-476	1	0.963
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	749-775	1	0.963
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66224-66254	2	0.935
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	449-479	2	0.935
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5019-5049	2	0.935
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	694-724	2	0.935
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9482-9512	2	0.935
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5020-5046	2	0.926
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	695-721	2	0.926
NZ_CP046109_1	1.3\|456\|27\|NZ_CP046109\|PILER-CR	456-482	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9483-9509	2	0.926
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	MT711976	Streptomyces phage Coruscant, complete genome	87403-87429	5	0.815
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31964-31990	5	0.815
NZ_CP046109_1	1.4\|510\|27\|NZ_CP046109\|PILER-CR	510-536	27	JQ660954	Clostridium phage PhiS63, complete genome	22891-22917	6	0.778
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31963-31993	7	0.774
NZ_CP046109_1	1.1\|449\|31\|NZ_CP046109\|CRISPRCasFinder	449-479	31	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	586541-586571	8	0.742
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	MT711976	Streptomyces phage Coruscant, complete genome	87400-87430	8	0.742
NZ_CP046109_1	1.2\|503\|31\|NZ_CP046109\|CRISPRCasFinder	503-533	31	JQ660954	Clostridium phage PhiS63, complete genome	22890-22920	10	0.677

1. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

2. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

3. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

4. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

5. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

6. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

7. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

8. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

9. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

10. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

11. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

12. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

13. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

14. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

15. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

16. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

17. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

18. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

19. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

20. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

21. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

22. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

23. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

24. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

25. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

26. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

27. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

28. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

29. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

30. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

31. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

32. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

33. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

34. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

35. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

36. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

37. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

38. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

39. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

40. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

41. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

42. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

43. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

44. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

45. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

46. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

47. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

48. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

49. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

50. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

51. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

52. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

53. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

54. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

55. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

56. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

57. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.968

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccaggacttt	Protospacer
************************* *****

58. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

59. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

60. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

61. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

62. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

63. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

64. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.963

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccaggac	Protospacer
************************ **

65. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

66. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

67. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

68. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

69. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

70. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

71. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

72. spacer 1.3|456|27|NZ_CP046109|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

73. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaagccaataaaaccactct	Protospacer
********** ******* **** * .

74. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
ttttgaagaatcctttaataccagtac	Protospacer
*.. *********  ************

75. spacer 1.4|510|27|NZ_CP046109|PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 6, identity: 0.778

tccagaagaatccaataataccagtac	CRISPR spacer
aaacgaagaaaccaataatatcagtac	Protospacer
    ****** *********.******

76. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 7, identity: 0.774

gtccagaagaatccaataataccagtacttt	CRISPR spacer
attttgaagaatcctttaataccagtactta	Protospacer
.*.. *********  **************

77. spacer 1.1|449|31|NZ_CP046109|CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.742

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
ccaccattaaaaatgataaaaacggcgtttt	Protospacer
*. * . **** ********* ********.

78. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 8, identity: 0.742

gtccagaagaatccaataataccagtacttt	CRISPR spacer
atccagaagaagccaataaaaccactctgtg	Protospacer
.********** ******* **** * . *

79. spacer 1.2|503|31|NZ_CP046109|CRISPRCasFinder matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 10, identity: 0.677

gtccagaagaatccaataataccagtacttt	CRISPR spacer
aaaacgaagaaaccaataatatcagtacaag	Protospacer
.    ****** *********.******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP046108

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP046109

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection