CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP050137	Sphingomonas sp. CL5.1 chromosome, complete genome	1 crisprs	DinG,cas3,DEDDh,csa3,WYL	0	0	3	0
NZ_CP050138	Sphingomonas sp. CL5.1 plasmid pTSSC1, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP050137_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP050137_1

3746443-3746547

Orphan

Consensus_repeat	Method
CCGGCGCGGAGGCGCGGCGGCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP050137_1

>merge|NZ_CP050137|1|3746443-3746547|CRISPRCasFinder
CCGGCGCGGAGGCGCGGCGGCTGCTCGCGGTGGGCCTCGCCAATTATGCCGCCGGCGCGCTGGTGATGCCCTATGCCGCGTTCCGCGCGGAGGCGCGGCGGCTGC

>NZ_CP050137|1|1|3746443-3746547|CRISPRCasFinder
CCGGCGCGGAGGCGCGGCGGCTGC	TCGCGGTGGGCCTCGCCAATTATGCCGCCGGCGCGCTGGTGATGCCCTATGCCGCGT
TCCGCGCGGAGGCGCGGCGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP050137.1\|WP_174838057.1\|3744098_3745625_-\|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|227136
NZ_CP050137.1\|WP_174838049.1\|3735231_3735834_+\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133025
NZ_CP050137.1\|WP_174839165.1\|3751449_3753729_+\|phosphoenolpyruvate--protein-phosphotransferase	unknown	unknown	gnl\|CDD\|226133
NZ_CP050137.1\|WP_174838048.1\|3734049_3735042_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176544
NZ_CP050137.1\|WP_174838054.1\|3742332_3743121_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235661
NZ_CP050137.1\|WP_174838066.1\|3756463_3757435_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_CP050137.1\|WP_174838053.1\|3740170_3742312_-\|methylmalonyl-CoA-mutase	unknown	unknown	gnl\|CDD\|236508
NZ_CP050137.1\|WP_174838061.1\|3748969_3750907_+\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677
NZ_CP050137.1\|WP_174838067.1\|3757496_3759464_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_CP050137.1\|WP_174838059.1\|3747301_3747832_+\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NZ_CP050137.1\|WP_174838065.1\|3755846_3756464_+\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NZ_CP050137.1\|WP_174838060.1\|3747847_3748864_-\|aldehyde-reductase	unknown	unknown	gnl\|CDD\|187538
NZ_CP050137.1\|WP_174838063.1\|3753845_3754781_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379173
NZ_CP050137.1\|WP_174838062.1\|3751041_3751275_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP050137.1\|WP_174838052.1\|3738899_3740174_-\|O-acetylhomoserine-aminocarboxypropyltransferase	unknown	unknown	gnl\|CDD\|180344
NZ_CP050137.1\|WP_174838050.1\|3735840_3737820_-\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|227111
NZ_CP050137.1\|WP_174838064.1\|3754847_3755771_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224643
NZ_CP050137.1\|WP_174838055.1\|3743260_3743680_-\|methylmalonyl-CoA-epimerase	unknown	unknown	gnl\|CDD\|319912
NZ_CP050137.1\|WP_174838051.1\|3737898_3738903_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|273075
NZ_CP050137.1\|WP_174838056.1\|3743676_3744102_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP050137.1\|WP_174838057.1\|3744098_3745625_-\|acyl-CoA-carboxylase-subunit-beta	gnl\|CDD\|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NZ_CP050137.1\|WP_174838049.1\|3735231_3735834_+\|nucleotidyltransferase-family-protein	gnl\|CDD\|133025	cd04182, GT_2_like_f, GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.71055e-35
NZ_CP050137.1\|WP_174838048.1\|3734049_3735042_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176544	cd08602, GDPD_ScGlpQ1_like, Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of putative bacterial and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDE, EC 3.1.4.46) similar to Escherichia coli periplasmic phosphodiesterase GlpQ, as well as plant glycerophosphodiester phosphodiesterases (GP-PDEs), all of which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. The prototypes of this family include putative secreted phosphodiesterase encoded by gene glpQ1 (SCO1565) from the pho regulon in Streptomyces coelicolor genome, and in plants, two distinct Arabidopsis thaliana genes, AT5G08030 and AT1G74210, coding putative GP-PDEs from the cell walls and vacuoles, respectively.	8.14244e-150
NZ_CP050137.1\|WP_174838054.1\|3742332_3743121_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235661	PRK05981, PRK05981, enoyl-CoA hydratase/isomerase.	5.53671e-95
NZ_CP050137.1\|WP_174838066.1\|3756463_3757435_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	3.10028e-63
NZ_CP050137.1\|WP_174838053.1\|3740170_3742312_-\|methylmalonyl-CoA-mutase	gnl\|CDD\|236508	PRK09426, PRK09426, methylmalonyl-CoA mutase; Reviewed.	0
NZ_CP050137.1\|WP_174838061.1\|3748969_3750907_+\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NZ_CP050137.1\|WP_174838067.1\|3757496_3759464_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_CP050137.1\|WP_174838059.1\|3747301_3747832_+\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.84376e-11
NZ_CP050137.1\|WP_174838065.1\|3755846_3756464_+\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	7.31649e-50
NZ_CP050137.1\|WP_174838060.1\|3747847_3748864_-\|aldehyde-reductase	gnl\|CDD\|187538	cd05227, AR_SDR_e, aldehyde reductase, extended (e) SDRs. This subgroup contains aldehyde reductase of the extended SDR-type and related proteins. Aldehyde reductase I (aka carbonyl reductase) is an NADP-binding SDR; it has an NADP-binding motif consensus that is slightly different from the canonical SDR form and lacks the Asn of the extended SDR active site tetrad. Aldehyde reductase I catalyzes the NADP-dependent reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.09172e-90
NZ_CP050137.1\|WP_174838063.1\|3753845_3754781_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379173	pfam13413, HTH_25, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.32228e-23
NZ_CP050137.1\|WP_174838052.1\|3738899_3740174_-\|O-acetylhomoserine-aminocarboxypropyltransferase	gnl\|CDD\|180344	PRK05994, PRK05994, O-acetylhomoserine aminocarboxypropyltransferase; Validated.	0
NZ_CP050137.1\|WP_174838050.1\|3735840_3737820_-\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	gnl\|CDD\|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_CP050137.1\|WP_174838064.1\|3754847_3755771_+\|hypothetical-protein	gnl\|CDD\|224643	COG1729, COG1729, Uncharacterized protein conserved in bacteria [Function unknown].	1.08137e-14
NZ_CP050137.1\|WP_174838055.1\|3743260_3743680_-\|methylmalonyl-CoA-epimerase	gnl\|CDD\|319912	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE). MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.	4.21933e-51
NZ_CP050137.1\|WP_174838051.1\|3737898_3738903_-\|biotin-synthase-BioB	gnl\|CDD\|273075	TIGR00433, biotin_synthase, biotin synthase. Catalyzes the last step of the biotin biosynthesis pathway. All members of the seed alignment are in the immediate gene neighborhood of a bioA gene. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	6.83614e-164
NZ_CP050137.1\|WP_174839165.1\|3751449_3753729_+\|phosphoenolpyruvate--protein-phosphotransferase	gnl\|CDD\|226133	COG3605, PtsP, Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms].	0

>NZ_CP050137.1|WP_174838057.1|3744098_3745625_-|acyl-CoA-carboxylase-subunit-beta
MSSTIEELERKRAAARLGGGQKRIDAQHAKGKLTARERIDVLLDEGSFEELDMFVEHNCVDFGMQDQVYPGDGVVTGSGTVNGRLVFVFSQDFTVFGGSLSERHAQKICKVMDMAMKVGAPVIGLNDSGGARIQEGVASLGGYAEVFQRNVLASGVVPQISVIMGPCAGGAVYSPAMTDFIFMVKDSSYMFVTGPDVVKTVTNEVVTQEALGGAVTHTTRTSVADNAFEDDIEALLAVRDFVDYLPESNRAAVPERPTDDPWDRLEAGLDTLIPPSANQPYDMHELIRKTVDEGDFFEIQPGHAGNIICGFGRIEGRTVGFVANQPMVLAGVLDINSSKKAARFVRFCDAFDIPIVTFVDVPGFLPGTAQEHNGIIKHGAKLLFAYAEATVPKITVITRKAYGGAYDVMASKHLRGDLNYAWPTAEIAVMGAKGAVEIIFRGLNEEGIAEKTREYEARFANPFVAASKGFIDEVIQPHSTRRRIALGLRKLRSKALENPWKKHDNIPL
>NZ_CP050137.1|WP_174838056.1|3743676_3744102_-|hypothetical-protein
MNGVVVALVGLVSAVLGGFMQARATRSFERLRFSRQAKWDLYSAFFVSLGELSFYARETSTHTAALASMAQIRARIALVGTHDVIESVAEVFRYRDLKTDAAQEAMAAALRAMRRDVGEVDRVIDPAILKAVMFRSSKDDL
>NZ_CP050137.1|WP_174838055.1|3743260_3743680_-|methylmalonyl-CoA-epimerase
MKLGRLNHIGVATPSIAKSVETYRLLLGAEKIGEPFDLPAQGVKVCFVDAPNTQIELIEPYDESSPIAGFLRKNPAGGQHHVCFEVPDIHAAVAHMKASGATVLGEPRIGAHGTPIVFVHPKDFGGMLVELMETPKEAH
>NZ_CP050137.1|WP_174838054.1|3742332_3743121_-|enoyl-CoA-hydratase/isomerase-family-protein
MAEYETILTEKKGDVLVITLNRPDRLNAASLQMAEDLCAALYDLQGARAVLITGAGRAFCSGADLQARGGASAVSGGDASHRALMNHYNPALSQIMRLDVPVVTAVNGAAAGVGCSIGLAGDFVLAGKSAYFLQAFVNIGLVPDGGSTWLLTRALGKPRATRMMMLGERIGAEQAEGWGLIYKAVDDVALMDEALALATRLAGGPTVALSAMRRNILTALDGSFEQVLRAEAEGQRLAGGTQDAREGGLAFLEKRKPVFKGA
>NZ_CP050137.1|WP_174838053.1|3740170_3742312_-|methylmalonyl-CoA-mutase
MTDIKPTLEDWSAAAAKEVKGKDLTWHTPEGIAVKPLYTAGDVAVDPGLPGFAPFTRGVRASMYAGRPWTIRQYAGFSTAEESNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHPRVVGDVGKAGVAIDSVEDMKILFDGIPLDQMSVSMTMNGAVIPILAFFIVAGEEQGVERKLLDGTIQNDILKEFMVRNTYIYPPEPSMRIISDIFGYTSREMPKFNSISISGYHMQEAGATQLQELAFTIADGAEYVKYGVASGLDIDKFAGRLSFFFAIGMNFFMEVAKLRAARVLWHRVMTKLGAKDERSKMLRTHCQTSGVSLTEQDPYNNVIRTTIEAMAAMLGGTQSLHTNALDEAIALPTDFSARIARNTQIVIQEETGMTKVVDPLGGSYYIESLTQQLVDGAWEIIERVEREGGMAKAVAAGWPKAMIEEASAARAARVDRGEDVIVGVNKYRLANEDEIEILDVDNHAVREAQIRRINKVKAERDEAACRAALDALREGAKGKGNLLELAVDAARARATLGEISSAMEDVFGRFGTFPTPVKGIYGGAYKDDGRWERLLGGVEATERRLGRKPRIFVAKMGQDGHDRGANLVSSMFGDLGFEVVAGPLFQTPQEAAALALEKDVDVVGASSLAAGHKTLIPELIGHLKDAGRADIKVVAGGVIPAQDYQALYDAGVQAIFGPGTNLIKAAEDVLRLLGHNMPPEQEAAE
>NZ_CP050137.1|WP_174838052.1|3738899_3740174_-|O-acetylhomoserine-aminocarboxypropyltransferase
MTQSIETLTVHAGTEPDPTTKARITPIYQTASYVFDSVDHAASLFNLDAFGNIYTRIMNPTNGAVEGKVAALEGGAAALAVASGHAAQFLTFHTLMEPGKHIVASKRLYGGSLNQIGSSFKKMAWDSTFVDADDPANVAAAITGDTRAVFIESLANPGGVVQDIEAIAKVAHDAGVPLIVDNTMATPILCRPIEHGADIVVHSLTKFLNGHGNSIGGVIVDAGSFDWAKGGKYPYLSQPNDSYHGKVFTEAFGNLAFILAARTLGLRDLGPALAPMNAFLALTGMETLALRMERHCDNALKLAEWLSNHPRVAWVSYAGLPGDKYHALAQRYLGGKGGAVFTFGLKGGYDAGIALVSKVKLFSHLANLGDTRSLIIHPASTTHRQLPDAERAAAGAGPDVVRVSVGIENIADIIADLEQALEAA
>NZ_CP050137.1|WP_174838051.1|3737898_3738903_-|biotin-synthase-BioB
MTTRNDWTRAEIAELFDLPFGELMYQAQTVHRAHHAANEVQMCTLLSIKTGGCPEDCGYCSQSAHAETGVKATRLMDVRAVLQMAAQAKDSGSQRFCMGAAWRNPKDRDMPAIVEMVRGVREMGMETCMTLGMLTPDQARQLADAGLDYYNHNIDTSPERYGEVITTRTFAERLDTLGHVREAGINVCCGGIVGMGETREDRVGFIHALATLPRHPESVPVNALVPVKGTVLGDMLADTPLAKIDDIEFVRTVAAARIAMPMSMVRLSAGRESMSEATQALCFMAGANSIFTGDKLLTTGNRGDSADAALFEKLGVRPMEAEEPMRQTVCEAAE
>NZ_CP050137.1|WP_174838050.1|3735840_3737820_-|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha
MFKKILVANRGEIACRVFRTAKKMGLKTVAVYSDADARAPHVLMADEAVRLGPAPAAESYLKAGLILEAAKATGADCIHPGYGFLSERESFARACAEAGIAFVGPPPKAIAAMGDKIESKKLAKAAGVNVVPGYLGEIADTEEAVKIAKDIGFPVMMKASAGGGGKGMRLAWSEQDVREGFEATKREGLASFGDDRVFIEKFIESPRHIEIQVLGDQHGNIVYLNERECSVQRRHQKVVEEAPSPFVTPKMRKAMGEQAVALARAVGYYSAGTVELIVSGADKTGESFYFLEMNTRLQVEHPVTEEITGLDLVEQMIRVAAGEKLSFGQKDVKINGWSVENRVYAEDPYRGFLPSIGRLVRYNPPAESDGVRVDDGVREGGEVSMFYDPMIAKLITHGKTREEAIDRQIDALDAFEIEGPGTNLDFVSALMQHPRFRSGNITTGFIAEEYPEGFHGAPASQELVRTLAGVAAFAAVAWAERARSVDGQLGGPLDPPADWVVRIDKRDHAVTVDGDEVTVDGKPLDGAIDYAPGDRTAIVDGKKPLTVKIARTRTGFTLNTRGASHKARVLPARIAPFARHLLEKVPPDLSKFLIAPMPGLLVRLDVKEGDKVEAGQPLAVVEAMKMENILRAEKSAVVKAVNAATGESLAVDQVILELE
>NZ_CP050137.1|WP_174838049.1|3735231_3735834_+|nucleotidyltransferase-family-protein
MIAVEKTVLVLLAAGKSRRFGDVGSKLDEMFLSRPLGLHVAVTLEDIPFMERIAIVDGLKIDYARHNFTVIHDENPERDMASAVRLGVEAARSHGAEAVIIALADMPRVTATHIYRLLDAADGPEAVVASSNGRHPSPPVLFGAARFGEVLAIRDDNDARDMIRAGVHVVANEQELIDVDTREELEQLRALVHAPEARRR
>NZ_CP050137.1|WP_174838048.1|3734049_3735042_-|glycerophosphodiester-phosphodiesterase
MPESIAPLSDPIVIAHRGASGERPEHTLAAYEFAIAEGADFIEPDLVPTKDNVLVARHENEISGTTDVADHPEFAARRTTRTIDGQKVSGWFVEDFTLAELKTLRAKERLPILRPDNRQYDGKFEIPTLAEIIALAKRHHVGIYPETKHPTYFASIGHPTDELLVRQLQAAGWNTPDAPVFIQSFEVDNLKRIHKLTGIRLIQLVDKEGGPADGATQSYAEMLTPEGMRGIATYAFGIGPNKAMLWDGKVPTGLIRAAHAAGLRVHPWTYRAENYFLPSGYRDGLNPRGHGDLDGEISDALYRGLDGFFTDFPAIGVAARNRVQAERSKK
>NZ_CP050137.1|WP_174838059.1|3747301_3747832_+|M23-family-metallopeptidase
MYRLPFADGTAVKVFDDFRSHRPRGRIDLYAVDGEKPYRVVAARAGRIVAIQDDYAEQQSGRPAAECHNNYVWIAHEDGEWSNYSHLAHHSVTGKAGLKVGDRVKAGAYLGDEGAVGCAMLDHVHFEVVRPPSGPGIDAGGFLLDNADSKRELEPRFCGVPRQTVVKDGTYIARPC
>NZ_CP050137.1|WP_174838060.1|3747847_3748864_-|aldehyde-reductase
MGGTVLVTGGSGYIAGFLIRLLVERGWTVNATIRNLAREPEVRAALGVPAERLRFFAADLERDDGWAAAMAGCTHVAHVASPFPAAKMPDEALIRPARDGALRALRFAKEAGVKRFVLTSSVAAVAYGHEPLDGGLYTEADWTDVTAPGISAYVKSKTIAERAARDWMAENGAGMEFCSVNPAAVLGPVMSADFSTSIQLVQRMLDGSLPGFPRIGFGVVDVRDLAELHLRALETPGLDGERFIGSGRFMMIEEGGAILRARLGEKARKVPKRRIPDFVVRLIGLFDGGVGQIVGELGRVRATDASHAERVLGWKTRDEGDSIVDTAESLIERGIVKV
>NZ_CP050137.1|WP_174838061.1|3748969_3750907_+|acetate--CoA-ligase
MAEQELYPVPAEWSAAAKVDHARYDAMYRASIGDPDGFWLEQAKRLDWVTAPTRAGDWSFDEDDFRIEWFRDGVLNVAANCIDRHLAERGDQVAIIWEPDDPKEEPRRYTYRQLHEEVCRFANVLKAQGVRKGDRVTVYLPMIPEAAFAVLACARIGAIHSVVFGGFSPDALAGRIQDCDSKIVVTADEGRRGGRRVPLKANVDEAATRTPSLEKVIVIKATGGDVAMGARDVWYHEAAEGVSTDCPAEPMAAEDPLFILYTSGSTGKPKGVLHTTGGYLLWAAFTHDLVFDYRPGNVFWCAADIGWVTGHTYILYGPLANGATTLMYEGLPNWPDASRIWQVIDRHQVHTVFTAPTALRALMKEGDEPVRRTSRASLRLLGTVGEPINPEAWRWYYDVVGEGRSPIVDTWWQTETGGALIAPLPGATGLKPGSATLPLPGVQPQLVDEAGNVLEGAASGNLCIVASWPGQMRTVWNDHARFFQTYFTTYRGKYFTGDGCRRDGDGYYWITGRVDDVINVSGHRMGTAEVESALVLHPQVAEAAVVGMPHEVKGQGIYAYVTLNAGEAASSDLNAALKQWVRKEIGPIATPDAIQFAPGLPKTRSGKIMRRILRKIAEGDTSNLGDISTLADPSVVEDLVANRIG
>NZ_CP050137.1|WP_174838062.1|3751041_3751275_+|hypothetical-protein
MAKHGSGTPLPPEEIERILWSARRAGTILILPREQPQLAIEALTDQGLVRRQLGHIVLTLQGQERRRKCAHYMAALA
>NZ_CP050137.1|WP_174839165.1|3751449_3753729_+|phosphoenolpyruvate--protein-phosphotransferase
MPLSAAASAREILVRLHDVMAARSNAQAKLNQVVEIIGEALDSEVCSIYLLREGVLELFATRGLDPAAVHVTKLALGEGLVGTIAADVEVLNLDEAASHPHFVYRPETGEDRFQSFAGVPIIRRERAVGVLAVQHHEARKYADVEIEALQTVAMVLSELIANAGLIDGPSGAADGTRPQSTASVRISGQKLVDGMAAGYAVFHQPRITIEHTVAEDTEAERHRVYAAFDKMREQIDRMTREAEFGVGGEHEEVLATYKMFAYDEGWGRRINEAIDSGLTAEAAIERVQQRTRQRMRQIDDPLLADRMHDLEDLSNRLLRIVSGQMGTAAQLGLRQDTILIARNLGPAELLEYDRRRLKGVILEEGSLTAHVTIVARAMGVPVLGRARDVRRLIADGDLLLLDVSEGSVVVRPSAGMEEAFDAKLALRQKRRAAYAALREVAPETKDGHRLTVMVNAGLRDDVAALDLTGADGIGLFRTEFQFLVSATLPSRERQQRLYREVLDAAGDRPVVFRTIDIGGDKALPYLKDDPAGEENPAMGWRALRLGLERDGLMKVQARALLEAAAGRTLNVMFPMVSEAWEFDEAHALFEAQRDWLAARGRRLPNEIRYGAMLEVPSLAYQLDLLLPKLQFLSIGTNDLTQFLFAADRANPKLAERYDWLSAAILRFVASVIEPARAAGVTLTVCGEMGGRPLEAMALIGLGIERLSITPAAVGPIKAMIRSLDRGAVMSEMQRLLAAPPRDFRGAIAAFAAAQGVELG
>NZ_CP050137.1|WP_174838063.1|3753845_3754781_+|helix-turn-helix-domain-containing-protein
MTDAAPGEQTTLFPRPVGERLRSAREAQGMSLAEIAARTRVPQRHLEAIENGSYDSLPSPTYAVGFVRAYARTVGEDEVDLARATREEVARIGRPVAQYQPYEIADPSRVPSRGLVIVAAGVALAVVVLAVLWFAVGMWRGSGGPGAAPAPAVSVPVPASHASATPQAGPGHVTLTASDSVWLRVYDADNKTLYLGTMKAGDRYDVPPDARDPKINVGRPDKLTVTLNGSALPPLGDGSHPIKDVPVSAAALAARVSAGSNATAAPAAGPSATPSPRASATPAAARPPAFADPAPAAPADAGNAAATDARD
>NZ_CP050137.1|WP_174838064.1|3754847_3755771_+|hypothetical-protein
MRKLVLLAGAAMCWAVPAAAQSGLDGRVGKLESEMRAVQRKVFPGGTPSIEPQITGAPAPEREIGAPATPVIADLTQRVGSLEQQMASMTGQIEQAQYRVRQLEEQFAAYRKEVDARFNSAGPAPGTGGPVESTGATTPAPAVPAPGRKPEASAPAPAAGKDPARAKLVAAIEKPSTAQPDEDDYIYGYRLWAAKLYPEAEAQFRKVVADYPRSRRASYAQNLLGRSYLDDGKPSLASIAFYDNYKKMPDGERAPESLYYLGQALMKLNKPADACKVYGELTDVYGAKIDAAMQANIARARVAAKCK
>NZ_CP050137.1|WP_174838065.1|3755846_3756464_+|trimeric-intracellular-cation-channel-family-protein
MGLPIESFLPWLDIAGLSVFAASGALAAARKRLDFVGACFFALITATGGGTLRDILIGAPIFWMHDPAPAILCVVIAVAAWLVPLRWWPERALDWFDAAGLAAYAVYGAGKALHFGISPIPAIAAGIITACIGGVIRDITAGVPSILMRHELYVTAALAAASVFVGLTLAGMAAPWPALIGFGLGFAMRGAAIRWKLALPPHRGS
>NZ_CP050137.1|WP_174838066.1|3756463_3757435_+|tRNA-lysidine(34)-synthetase-TilS
MPSPAAIDRFRADLARVAPGTGRLALAVSGGPDSMVLLALAHAALPAGGVIAATVDHRLRPAAAEEAAMVARHCAALGVPHTILAPSGPIAGASIQALAREARYALLADWAREHRADALATAHHADDQAETFVMRAARGSGVAGLSGVRARAVIAGFPVARPLLGWRRAELRAIAAAAAAPFVDDPSNADPRHDRTRFRALLAATPALDPLALARSAAALAEAEEALAWNVERLWAERARDDSPLTLDVAGLPRELRRRLARRAIAETRARHAVTAPPWSEAANIEPLLDSLEAGARATQAGVMLTPRGDSWTVAKAPPRRSH
>NZ_CP050137.1|WP_174838067.1|3757496_3759464_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MIDKDKQPGSDNNGGGPNPWMKSLLIWVGILLALALVVTMFDSKTPAAQGNTIAYSTFLDKVDQGTVKDVNVSRDMITGTFKSGDKFKTYPVTDPQLTDRLRKASVAISGKPEDGPSIWQYVLVQALPFMLFLGIAFLVMRQMQKGGGSGAMGFGKSRARMLTQKEGKVTFDDVAGIDEAREELQEIVEFLKDPSKFARLGGKIPKGALLVGSPGTGKTLLARAIAGEAGVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKSAPCIVFIDEIDAVGRHRGAGLGNGNDEREQTLNQLLVEMDGFEANEGIIIIAATNRPDVLDPALLRPGRFDRQVVVPRPDIEGRVKILEVHMKKVPLAPDVDSRTIARGTPGFSGADLANLVNEAALTAARKGKRLVAMAEFEEAKDKVMMGAERRSMVMTEDEKRMTAYHEAGHAIVALHEPASDPIHKATIIPRGRALGMVMRLPERDSYSYHRDKMYANLAVSMGGRVAEEIIFGYDKVSSGASGDIQYATGLARDMVTKWGMSDKVGPVEYSQPEGESFLGYSSSQPVRMSNQTQQLIDDEIRTIVEGGLARAKQVLGEHIDQLHSLAGALLEYETLTGDEIKKLIAGEEIGRADHGPKAAAVRAAGTSIPKTRRPTGPFGNPSPAGA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

107206 : 165479

Leptospira_phage(33.33%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174834841.1\|107206_108377_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.7e-37	36.8
WP_174834842.1\|108432_108948_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_174838741.1\|108963_109725_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_174834843.1\|110902_111424_-	flavin reductase family protein	NA	NA	NA	NA
WP_174834844.1\|111408_112179_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_174834845.1\|112181_113018_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_174834846.1\|113022_113481_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_174834847.1\|113528_114275_-	glucose 1-dehydrogenase	NA	NA	NA	NA
WP_174838743.1\|114318_116844_-	TonB-dependent receptor	NA	NA	NA	NA
WP_174838744.1\|117043_117688_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_174834848.1\|118008_118766_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_174834849.1\|119362_120454_-	alcohol dehydrogenase catalytic domain-containing protein	E3SJ82	Synechococcus_phage	1.5e-15	24.1
WP_174838745.1\|120513_121620_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_174834850.1\|121679_122834_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_174834851.1\|123019_124624_+	acyl--CoA ligase	A0A1V0SBX8	Catovirus	2.0e-08	24.8
WP_174834852.1\|124620_125025_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_174834853.1\|125014_125677_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_174834854.1\|125767_126919_+	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_174834855.1\|127014_127722_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_174834856.1\|127918_128629_+	DUF2889 domain-containing protein	NA	NA	NA	NA
WP_174834857.1\|128625_129747_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	2.9e-54	36.0
WP_174834858.1\|129822_130140_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_174834859.1\|130149_131415_-	cytochrome P450	NA	NA	NA	NA
WP_174834860.1\|131554_132244_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_174838746.1\|132547_133753_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_174834861.1\|134000_134231_+\|transposase	transposase	S5WIU1	Leptospira_phage	1.3e-06	48.8
WP_174834862.1\|135470_136562_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_174838748.1\|136539_137970_-	mannitol dehydrogenase family protein	G8DCZ3	Micromonas_pusilla_virus	1.8e-48	32.8
WP_174834863.1\|137969_139412_-	glucuronate isomerase	NA	NA	NA	NA
WP_174834864.1\|139498_141013_+	altronate dehydratase	NA	NA	NA	NA
WP_174838749.1\|141184_142336_+	MFS transporter	NA	NA	NA	NA
WP_174834865.1\|142427_144479_+	acetylxylan esterase	NA	NA	NA	NA
WP_174834866.1\|144528_145995_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_174838751.1\|149237_150788_+	glycoside hydrolase family 28 protein	NA	NA	NA	NA
WP_174834867.1\|150982_152449_+	Ig-like domain-containing protein	NA	NA	NA	NA
WP_174834868.1\|152445_152613_+	hypothetical protein	NA	NA	NA	NA
WP_174834869.1\|152622_153633_+	sugar kinase	NA	NA	NA	NA
WP_174834870.1\|156355_157912_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_174834871.1\|158508_159246_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	4.2e-22	33.3
WP_174838752.1\|159295_160435_-	hypothetical protein	NA	NA	NA	NA
WP_174834872.1\|160431_161661_-	cytochrome P450	NA	NA	NA	NA
WP_174834873.1\|161671_162331_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_174834874.1\|162611_164147_+	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	3.8e-25	25.6
WP_174834841.1\|164307_165479_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	9.7e-37	36.8

DBSCAN-SWA_2

1225754 : 1255246

Bathycoccus_sp._RCC1105_virus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174835818.1\|1225754_1226051_-\|transposase	transposase domain-containing protein	NA	NA	NA	NA
WP_174834728.1\|1226369_1226645_+	hypothetical protein	NA	NA	NA	NA
WP_174835819.1\|1226599_1228033_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_174835820.1\|1228032_1229559_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_174835821.1\|1229558_1230785_-	HlyD family secretion protein	NA	NA	NA	NA
WP_174834729.1\|1231166_1231316_+	hypothetical protein	NA	NA	NA	NA
WP_174835822.1\|1231312_1231783_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_174835823.1\|1231774_1232164_-	PaaI family thioesterase	NA	NA	NA	NA
WP_174835824.1\|1232178_1232634_-	PaaI family thioesterase	NA	NA	NA	NA
WP_174835825.1\|1232718_1233696_+	MCE family protein	NA	NA	NA	NA
WP_174835826.1\|1233661_1233997_-	hypothetical protein	NA	NA	NA	NA
WP_174838906.1\|1234167_1234925_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_174835827.1\|1235054_1236086_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_174835828.1\|1236283_1236871_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_174838908.1\|1238540_1239179_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_174835829.1\|1239178_1240789_+	ubiquinone biosynthesis protein	E5EQY1	Bathycoccus_sp._RCC1105_virus	2.1e-26	27.2
WP_174835830.1\|1240913_1241861_+\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	1.5e-08	20.3
WP_174835831.1\|1242497_1244282_-	DUF1446 domain-containing protein	NA	NA	NA	NA
WP_174835832.1\|1244278_1245484_-	CoA transferase	NA	NA	NA	NA
WP_174835833.1\|1245492_1248381_-	TonB-dependent receptor	A0A0P0I887	Acinetobacter_phage	2.4e-12	35.5
WP_174838909.1\|1248450_1249701_-	MFS transporter	NA	NA	NA	NA
WP_174835834.1\|1249925_1250447_+	MaoC family dehydratase N-terminal domain-containing protein	NA	NA	NA	NA
WP_174835835.1\|1250443_1250848_+	acyl dehydratase	NA	NA	NA	NA
WP_174835836.1\|1250844_1251204_+	hypothetical protein	NA	NA	NA	NA
WP_174835837.1\|1251200_1252364_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_174835838.1\|1252482_1253220_+	IclR family transcriptional regulator	NA	NA	NA	NA
WP_174838910.1\|1253719_1255246_-\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	9.8e-82	36.6

DBSCAN-SWA_3

2097906 : 2112403

Bacillus_phage(27.27%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174836529.1\|2097906_2099199_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	3.1e-12	24.5
WP_174836531.1\|2099182_2099917_-	response regulator	W8CYM9	Bacillus_phage	3.1e-25	31.3
WP_007404630.1\|2100142_2100349_+	30S ribosomal protein S21	M1HLV7	Pelagibacter_phage	1.3e-05	49.2
WP_174836532.1\|2100448_2101015_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_174836534.1\|2101141_2101924_-	serine/threonine protein phosphatase	A0A1V0EF12	Caulobacter_phage	3.4e-30	38.4
WP_174836536.1\|2102013_2103309_-	UDP-N-acetyl-D-mannosamine dehydrogenase	M1HZW8	Acanthocystis_turfacea_Chlorella_virus	1.9e-25	29.2
WP_174836538.1\|2103295_2104411_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	NA	NA	NA	NA
WP_174836539.1\|2104530_2105400_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	9.6e-66	47.9
WP_174836541.1\|2105396_2106395_+	SDR family NAD(P)-dependent oxidoreductase	A0A0E3IB24	Synechococcus_phage	4.5e-27	30.9
WP_174836543.1\|2106575_2106818_-	hypothetical protein	NA	NA	NA	NA
WP_174836545.1\|2106915_2107674_-	molybdopterin-synthase adenylyltransferase MoeB	A0A291ATS8	Pandoravirus	1.2e-08	35.3
WP_174839014.1\|2107670_2108066_-	hypothetical protein	NA	NA	NA	NA
WP_174836547.1\|2108065_2108512_-	dUTP diphosphatase	K4JSC8	Caulobacter_phage	1.1e-36	55.0
WP_174836549.1\|2108561_2109743_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	1.0e-38	34.7
WP_174836551.1\|2109739_2110861_-	hypothetical protein	NA	NA	NA	NA
WP_174836552.1\|2110864_2112403_-	2-polyprenylphenol 6-hydroxylase	A0A2N9QVT9	Dishui_lake_phycodnavirus	4.4e-29	25.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage