CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053800	Vibrio cholerae strain SO5Y chromosome 1, complete sequence	1 crisprs	cas3,DEDDh,DinG,csx1,WYL,csa3	0	1	4	0
NZ_CP053801	Vibrio cholerae strain SO5Y chromosome 2, complete sequence	0 crisprs	csa3	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053800_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053800_1

2563367-2563610

Orphan

Consensus_repeat	Method
AAAATGTGCCTCCTTAGCTCAGTCGGTAGAGCAACGGACTGATAATCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP053800_1

>merge|NZ_CP053800|1|2563367-2563610|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAATTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAATTGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

>NZ_CP053800|1|1|2563367-2563610|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGG	TCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAA
TTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTG	TCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAAT
TGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053800.1\|WP_046127147.1\|2573165_2573546_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP053800.1\|WP_001087261.1\|2555149_2555707_+\|YggT-family-protein	unknown	unknown	gnl\|CDD\|223833
NZ_CP053800.1\|WP_175235840.1\|2563902_2565528_+\|cache-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP053800.1\|WP_001230176.1\|2562007_2563135_+\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
NZ_CP053800.1\|WP_046127146.1\|2567589_2569935_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP053800.1\|WP_000973544.1\|2574515_2575013_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_CP053800.1\|WP_054103761.1\|2569987_2571283_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP053800.1\|WP_000805056.1\|2558568_2559489_-\|glutaminase-B	unknown	unknown	gnl\|CDD\|234880
NZ_CP053800.1\|WP_046127141.1\|2556543_2557146_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP053800.1\|WP_046127142.1\|2557139_2558315_+\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550
NZ_CP053800.1\|WP_046127145.1\|2566576_2567431_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP053800.1\|WP_000035028.1\|2573556_2574366_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|234673
NZ_CP053800.1\|WP_046127379.1\|2560558_2561620_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|182805
NZ_CP053800.1\|WP_001243262.1\|2572278_2573094_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP053800.1\|WP_000741915.1\|2555706_2555997_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP053800.1\|WP_000095776.1\|2571272_2572265_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP053800.1\|WP_001233674.1\|2556042_2556474_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616
NZ_CP053800.1\|WP_175235838.1\|2559599_2560319_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP053800.1\|WP_000124738.1\|2561633_2561906_+\|oxidative-damage-protection-protein	unknown	unknown	gnl\|CDD\|180059
NZ_CP053800.1\|WP_000954087.1\|2575025_2575499_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|182143

Protein	Function_ID	Function_description	E-value
NZ_CP053800.1\|WP_046127147.1\|2573165_2573546_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	5.61158e-75
NZ_CP053800.1\|WP_001087261.1\|2555149_2555707_+\|YggT-family-protein	gnl\|CDD\|223833	COG0762, COG0762, Predicted integral membrane protein [Function unknown].	2.77868e-12
NZ_CP053800.1\|WP_175235840.1\|2563902_2565528_+\|cache-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	9.71305e-59
NZ_CP053800.1\|WP_001230176.1\|2562007_2563135_+\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	9.42926e-157
NZ_CP053800.1\|WP_046127146.1\|2567589_2569935_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP053800.1\|WP_000973544.1\|2574515_2575013_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	5.65999e-91
NZ_CP053800.1\|WP_054103761.1\|2569987_2571283_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	5.01688e-157
NZ_CP053800.1\|WP_000805056.1\|2558568_2559489_-\|glutaminase-B	gnl\|CDD\|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
NZ_CP053800.1\|WP_046127141.1\|2556543_2557146_+\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	6.67552e-126
NZ_CP053800.1\|WP_046127142.1\|2557139_2558315_+\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
NZ_CP053800.1\|WP_046127145.1\|2566576_2567431_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	2.07934e-153
NZ_CP053800.1\|WP_000035028.1\|2573556_2574366_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|234673	PRK00166, apaH, symmetrical bis(5'-nucleosyl)-tetraphosphatase.	2.28145e-170
NZ_CP053800.1\|WP_046127379.1\|2560558_2561620_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP053800.1\|WP_001243262.1\|2572278_2573094_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.27746e-146
NZ_CP053800.1\|WP_000741915.1\|2555706_2555997_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	9.17224e-61
NZ_CP053800.1\|WP_000095776.1\|2571272_2572265_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP053800.1\|WP_001233674.1\|2556042_2556474_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	6.80534e-67
NZ_CP053800.1\|WP_175235838.1\|2559599_2560319_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.52726e-110
NZ_CP053800.1\|WP_000124738.1\|2561633_2561906_+\|oxidative-damage-protection-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	5.47988e-59
NZ_CP053800.1\|WP_000954087.1\|2575025_2575499_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|182143	PRK09917, PRK09917, threonine/serine exporter.	7.45224e-67

>NZ_CP053800.1|WP_001230176.1|2562007_2563135_+|membrane-bound-lytic-murein-transglycosylase-MltC
MRKLVLCITALLLSGCSREFIEKIYDVDYEPTNRFAKNLAELPGQFQKDTAALDALINSFSGNIEKRWGRRELKIAGKNNYVKYIDNYLSRSEVNFTEGRIIVETVSPIDPKAHLRNAIITTLLTPDDPAHVDLFSSKDIELKGQPFLYQQVLDQDGQPIQWSWRANRYADYLIANHLKVKQVDFKKAYYVEIPMVKDQIDIRGYKYASIVRKASRKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKNRSGEPSPEYLFNPENNIDTGTAYFYILKNRYLKEVRHPTSLEYSMISAYNGGTGGVLSTFSSDRQRAMRDLNALQPNQVYWALTKKHPNAEARRYLEKVTKFKKEFNAG
>NZ_CP053800.1|WP_000124738.1|2561633_2561906_+|oxidative-damage-protection-protein
MARTVFCTRLQKEADGLDFQLYPGELGKRIFDNICKEAWAQWQTKQTMLINEKKLNMMDPEHRKLLEQEMVNFLFEGKEVHIEGYTPPAK
>NZ_CP053800.1|WP_046127379.1|2560558_2561620_+|A/G-specific-adenine-glycosylase
MTPFAQAILTWYDAYGRKNLPWQQNKNAYRVWLSEIMLQQTQVATVIPYFERFLERFPTVHALAAAPQDEVLHFWTGLGYYARARNLHKAAKMVVSEYGGEFPTDLEQMNALPGVGRSTAAAVLSSVYKKPHAILDGNVKRTLARCFAVEGWPGQKSVENQLWHYAEMHTPSVDVDKYNQAMMDMGAMICTRSKPKCSLCPVESFCLAKQQGNPQEYPGKKPKTDKPVKATWFVMLYHDNAVWLEQRPQSGIWGGLYCFPQSEIANIQTTIDQRAIGDSTITSQKTLIAFRHTFSHYHLDITPILLQLSRKPDIVMEGSKGLWYNLSQPDEIGLAAPVKQLLHSLPFDIDSHI
>NZ_CP053800.1|WP_175235838.1|2559599_2560319_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVITQEYTEDGKVLRRIRSFVRREGRLTKGQEAAMKECWPTMGIDYQPELLDWQQVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHDAVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLIIGSGVFHMATDWQNYAEHMIEVMNQAPGFANLATDGDYIPRPDERPLTKFEQRGYRLGHGVWDIKYQRTA
>NZ_CP053800.1|WP_000805056.1|2558568_2559489_-|glutaminase-B
MKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVITAGDAQEGFSIQSISKVLSLTLAMGLYQPDELWSRVGKEPSGQAFNSLIQLEMEHGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIAYDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSKQTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF
>NZ_CP053800.1|WP_046127142.1|2557139_2558315_+|radical-SAM-family-heme-chaperone-HemW
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGDIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEGIARLLQGVAKRIAFKPDIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAQLAHQIGLNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWAISEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE
>NZ_CP053800.1|WP_046127141.1|2556543_2557146_+|XTP/dITP-diphosphatase
MKKILLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLVAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTAPHGSNGFGYDPIFWVPEENCASAELEPGRKKQLSHRGKALQKLFKAIEEQRTC
>NZ_CP053800.1|WP_001233674.1|2556042_2556474_+|DUF4426-domain-containing-protein
MRKWMMSLLLTLLALPASAEQQKTIKDIEVHYSAFNSTFLTPKVASSYQLTRNGYTAILNISVLDRASLGKPATEAKLTGHAKNLIGNLRELSFKQVKEGNAIYYLAEVPISNEEMLTFDIDVDAGLKGAGKLTFSQKFYTEQ
>NZ_CP053800.1|WP_000741915.1|2555706_2555997_+|YggU-family-protein
MAAVWREGDDLLLRLYIQPKASRDSIVGLHGEELKVAITAPPIDGKANAHLSKYLAKLCKVAKGSVVIEKGELGRHKQVRILQPSQIPAEITALIE
>NZ_CP053800.1|WP_001087261.1|2555149_2555707_+|YggT-family-protein
MNSLSFLINTLFDLYIMVVILRIWLQAARADFYNPFSQFIVKATQPVVGPLRRVIPSIGSIDLATIVFAYVLCVLKFMALVLIASSGSVSFSADFLFLGLLSLIKAAGGLLFWVLLIRAILSWVSQGRSPIEYVFHQLTEPMLAPIRRIIPVMGGFDLSILVLFIVLQFANFLMGDVIGPIWYQL
>NZ_CP053800.1|WP_175235840.1|2563902_2565528_+|cache-domain-containing-protein
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLHHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFAIQAPKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVADLDQDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVDALESVSSMSHQIATAAAEQTQVSDDISRRINMIEESGSKLSRVVIESHNSTQTLTKLARELEQWAAHFEVTR
>NZ_CP053800.1|WP_046127145.1|2566576_2567431_-|co-chaperone-DjlA
MHIFGKILGAFFGFLFGGPFGAIFGIFLGHQFDKARRLNQAGFQSGTFGAGPSQAERQEEFFKSAFSVMGHVAKAKGQVTKEEIQLATIMMDRMNLNLEQKRAAQDAFRDGKESDFPLEQVLERVKIATGGRFDLLQFFLELQVSSAFADGDVHPSERQVLHRIARGLGFSSEQLERRLRMQEAAFRFQQGGGFGGSQQQSHSGQQWQQPSSRHQLADAYEVLGVSESASAQEVKRAYRKLMNEHHPDKLMAKGLPPEMMNVAKEKSQQIQHAYELIRKEKGIK
>NZ_CP053800.1|WP_046127146.1|2567589_2569935_+|LPS-assembly-protein-LptD
MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLAEDQLHTELGARWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSHIDSGIGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTEDKNRSNLPYRLMPQLSYNYYAPETMKYLDLDLVSHISRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVARVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTELQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNDNSKDKESSYSAWAVEMDFNFADYLFYHGGIQYDINGQAVQLGNSTLEYRFAGGYLQTNYRYVDKDYICSVRGCSSDGYSSLTKDGISQAGLLASYQLTRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFSYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
>NZ_CP053800.1|WP_054103761.1|2569987_2571283_+|peptidylprolyl-isomerase-SurA
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISHIQLRVDDGQDKSAAETLANKLVNDLKNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPTIFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDKTDSALKNKAYRILFNRKFNEEASAWLQELRASAFVEVLKDEKDEQ
>NZ_CP053800.1|WP_000095776.1|2571272_2572265_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSSKRIIVTAGEPAGIGPDLVLALSAQDWPHQLVVCADKALLAQRAVQLGIQVKLLDYQRDNPVQAQQAGTLLVEHIPLAEPVVAGQLNPANGHYVLKTLERAAKGCMNGEFDAIVTGPVHKGVINRAGVAFSGHTEFFAEQSKTPLVVMMLATEGLRTALVTTHLPLAEVPQAITCERLEQIVHILHKDLVEKFAIAEPKIYVCGLNPHAGEDGVLGMEEIETITPTLQRLREQYGMQLVGPLPADTIFSEKYLQQADAVLGMYHDQVLPVLKYKGFGRSVNITLGLPFIRTSVDHGTALDLAGTGQADAGSFWTALAYAIELVDKKAQ
>NZ_CP053800.1|WP_001243262.1|2572278_2573094_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MRNDVHLGHKARKRFGQNFLNDPYIIDGIVSAINPKPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELASKLTIHEGDAMRFDFKQLVKPNNKLRVFGNLPYNISTPLMFHLFEFHRDIQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYYCKVVPVLEVPPSAFVPPPKVDSAVVRLVPYEDLPHPATSLEWLDRVVREGFNQRRKTVRNCYKGLAEPETLETLGINPGMRPENLTLAQFVALANWLDATHKTHA
>NZ_CP053800.1|WP_046127147.1|2573165_2573546_+|Co2+/Mg2+-efflux-protein-ApaG
MDVSQPCIKIQVQTRYIEEQSNPEYQRFVFAYLITIKNLSSQTVQLMSRRWLITDADGKQTVVEGDGVVGEQPRIKANDEYTYSSGTALDTPVGVMQGQYLMIDEQGESFTVEIEPFRLAVPHVLN
>NZ_CP053800.1|WP_000035028.1|2573556_2574366_+|symmetrical-bis(5'-nucleosyl)-tetraphosphatase
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFVYQLGDAARVVLGNHDLHLLSVALGHHPAKRRDQTQAILDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIGLDTGCVWGGTLTMLRWEDKHYFSQAALPA
>NZ_CP053800.1|WP_000973544.1|2574515_2575013_-|type-3-dihydrofolate-reductase
MMISMIAAMADQRIIGKDNQMPWHLPADFAWFKRCTLGKPVVMGRKTYQSIGRPLPGRHNIVISRDVSLQIEGVDVVTSIEAALAKAGEVDEVMIIGGGSLYAACLPMAHKLYITEIHAKLEGDTQFPEWGSDWLERFREHYPADEKNAYGMDFVIFERQYPLPT
>NZ_CP053800.1|WP_000954087.1|2575025_2575499_-|threonine/serine-exporter-family-protein
MLSWDLFFGLLNDMFFAAIPAVGFALVFNVPVPALKYCALGGALGHGSRYLMMHFGVPIEWASFFAATLVGMVGVYWSRRFLAHPKVFTVAALIPMVPGVFAFKAMIALVEINHVGFSPELMEALLENFLKAMFIIAGLAVGLAVPGLLFYRRKPII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053800_1	1.1\|2563416\|37\|NZ_CP053800\|PILER-CR	2563416-2563452	37	NC_049942	Escherichia phage JLK-2012, complete sequence	23524-23560	4	0.892
NZ_CP053800_1	1.1\|2563416\|37\|NZ_CP053800\|PILER-CR	2563416-2563452	37	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35428-35464	4	0.892

1. spacer 1.1|2563416|37|NZ_CP053800|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
caggtcgccagttcgattccggtagccggcaccatat	Protospacer
.*********************.***********. *

2. spacer 1.1|2563416|37|NZ_CP053800|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
taggtcaccagttcgattccggtagccggcaccaatc	Protospacer
******.***************.*********** *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

654834 : 661452

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000210573.1\|654834_655968_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4
WP_000366562.1\|655979_657230_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000543544.1\|657330_657780_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_175235565.1\|657805_658909_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.0e-43	32.9
WP_000493874.1\|658913_659567_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001122865.1\|659607_660717_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000864130.1\|660981_661452_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7

DBSCAN-SWA_2

1510148 : 1536470

Vibrio_phage(78.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000948763.1\|1510148_1510460_+	hypothetical protein	E3U9J1	Vibrio_phage	6.6e-09	100.0
WP_149595898.1\|1510594_1510954_+	regulator	G8IRV3	Vibrio_phage	8.5e-61	93.2
WP_175235884.1\|1511023_1511344_-	hypothetical protein	NA	NA	NA	NA
WP_102786847.1\|1511429_1511672_-	ADP-ribosyl-(dinitrogen reductase) hydrolase	NA	NA	NA	NA
WP_102786846.1\|1511962_1512160_-	YegP family protein	NA	NA	NA	NA
WP_175235671.1\|1513016_1514384_-	toxin	Q64EV0	Vibrio_phage	9.9e-259	97.1
WP_001160095.1\|1514386_1514731_-	DUF2523 domain-containing protein	Q64EV1	Vibrio_phage	4.8e-61	100.0
WP_095467298.1\|1514730_1516071_-	hypothetical protein	G8IRU9	Vibrio_phage	1.5e-49	60.2
WP_000672170.1\|1516203_1516413_-	hypothetical protein	G8IRU8	Vibrio_phage	1.1e-20	81.2
WP_001900021.1\|1516446_1516677_-	hypothetical protein	G8IRU7	Vibrio_phage	3.9e-35	94.7
WP_001284206.1\|1516686_1517025_-	DUF1293 domain-containing protein	Q858R2	Vibrio_phage	1.3e-55	96.4
WP_001112192.1\|1517029_1518133_-	replication initiation factor domain-containing protein	Q64EV8	Vibrio_phage	1.5e-220	100.0
WP_000502184.1\|1518122_1518326_-	hypothetical protein	C3W4P3	Vibrio_phage	2.7e-35	100.0
WP_001018568.1\|1518336_1518585_-	hypothetical protein	O56843	Vibrio_virus	1.8e-22	65.9
WP_148520450.1\|1518763_1519120_+	regulator	Q9MCC3	Vibrio_phage	4.8e-32	57.9
WP_175235673.1\|1519443_1533081_-	MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA	B3Y8K3	Vibrio_virus	8.4e-07	100.0
WP_001881196.1\|1533104_1533566_-	RTX toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
WP_001906284.1\|1533591_1533939_-	hypothetical protein	NA	NA	NA	NA
WP_154401350.1\|1534364_1536470_+	RTX toxin T1SS ABC transporter subunit RtxB	W8CYL7	Bacillus_phage	1.1e-38	26.9

DBSCAN-SWA_3

2262236 : 2269429

Anguillid_herpesvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162850.1\|2262236_2262665_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4
WP_000107237.1\|2262868_2264158_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	1.7e-34	34.3
WP_000872176.1\|2264377_2264572_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_001124187.1\|2264620_2264959_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_001196545.1\|2264972_2266823_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.5e-105	40.9
WP_001105750.1\|2266846_2267362_-	co-chaperone HscB	NA	NA	NA	NA
WP_000301571.1\|2267410_2267734_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_000331703.1\|2267794_2268178_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_046126449.1\|2268214_2269429_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5

DBSCAN-SWA_4

2501023 : 2508248

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001279365.1\|2501023_2501911_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1
WP_025984303.1\|2502178_2504767_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_000116739.1\|2504860_2505868_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_000177561.1\|2505941_2506877_-	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000002982.1\|2506876_2507503_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_175235832.1\|2507495_2508248_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.1e-68	52.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP053801

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

321479 : 356213

Staphylococcus_prophage(30.0%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001898459.1\|321479_322439_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.3e-44	37.5
WP_175235977.1\|322673_323036_+	hypothetical protein	NA	NA	NA	NA
WP_057556422.1\|323177_323714_+	hypothetical protein	NA	NA	NA	NA
WP_050559285.1\|323810_324164_+	DUF4144 domain-containing protein	NA	NA	NA	NA
WP_175236095.1\|324424_324685_+	DUF3709 domain-containing protein	NA	NA	NA	NA
WP_108244118.1\|325252_325291_+	hypothetical protein	NA	NA	NA	NA
WP_046126196.1\|325485_326022_+	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_095466608.1\|326234_326501_+	hypothetical protein	NA	NA	NA	NA
WP_032473240.1\|326813_326996_+	DUF645 family protein	NA	NA	NA	NA
WP_175235979.1\|327197_327584_+	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_032469024.1\|327811_328090_+	DUF3709 domain-containing protein	NA	NA	NA	NA
WP_046127315.1\|328402_328573_+	hypothetical protein	NA	NA	NA	NA
WP_046126173.1\|328572_328974_+	type II toxin-antitoxin system death-on-curing family toxin	A0A222YZ88	Escherichia_phage	2.1e-07	29.8
WP_094393050.1\|329113_330004_+	hypothetical protein	NA	NA	NA	NA
WP_142741056.1\|331664_331946_+	hypothetical protein	NA	NA	NA	NA
WP_046126178.1\|332116_332512_+	DUF3465 domain-containing protein	NA	NA	NA	NA
WP_000691786.1\|333299_333935_+	DUF2807 domain-containing protein	NA	NA	NA	NA
WP_001896359.1\|335099_336020_+\|transposase	IS5-like element ISVch8 family transposase	A0A1V0E8E1	Vibrio_phage	6.0e-159	88.7
WP_032473262.1\|336768_336948_+	DUF645 family protein	NA	NA	NA	NA
WP_033839086.1\|337243_337732_+	RDD family protein	NA	NA	NA	NA
WP_019830302.1\|337876_338293_+	DUF1311 domain-containing protein	NA	NA	NA	NA
WP_175235981.1\|338451_339225_+	NERD domain-containing protein	A0A2R2ZH57	Clostridioides_phage	9.2e-28	36.5
WP_142741528.1\|339360_339870_+	AAA family ATPase	A0A097BYE2	Leuconostoc_phage	1.7e-06	25.6
WP_071180824.1\|340028_340442_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_080476722.1\|340757_340922_+	DUF645 family protein	NA	NA	NA	NA
WP_175235983.1\|341462_341567_+	acetyltransferase	NA	NA	NA	NA
WP_000422095.1\|341550_342024_+	hypothetical protein	NA	NA	NA	NA
WP_057561119.1\|342151_342640_+	dual specificity protein phosphatase family protein	A0A2H4UUE0	Bodo_saltans_virus	4.1e-05	33.3
WP_001898459.1\|342662_343622_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.3e-44	37.5
WP_142547423.1\|343988_344162_+	DUF3709 domain-containing protein	NA	NA	NA	NA
WP_017044877.1\|344495_345152_+	hypothetical protein	NA	NA	NA	NA
WP_142741524.1\|345287_345629_+	hypothetical protein	NA	NA	NA	NA
WP_175235984.1\|345768_346632_+	hypothetical protein	NA	NA	NA	NA
WP_001896359.1\|346935_347856_+\|transposase	IS5-like element ISVch8 family transposase	A0A1V0E8E1	Vibrio_phage	6.0e-159	88.7
WP_175235986.1\|347981_348332_+	hypothetical protein	NA	NA	NA	NA
WP_175236097.1\|348337_348493_+	DUF3265 domain-containing protein	NA	NA	NA	NA
WP_123012141.1\|348492_348618_+	DUF3709 domain-containing protein	NA	NA	NA	NA
WP_142741522.1\|348638_348860_+	DUF3709 domain-containing protein	NA	NA	NA	NA
WP_142741520.1\|349138_349915_+\|holin	choline kinase	NA	NA	NA	NA
WP_175235988.1\|350208_350391_+	DUF645 family protein	NA	NA	NA	NA
WP_000107461.1\|350649_350892_+	hypothetical protein	NA	NA	NA	NA
WP_001287986.1\|351599_352025_+	riboflavin-specific deaminase	A0A1V0SE20	Indivirus	5.4e-22	54.0
WP_000256034.1\|352171_352606_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_043993103.1\|352834_353101_+	hypothetical protein	NA	NA	NA	NA
WP_142741518.1\|353302_354289_-	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_142576968.1\|354542_354923_+	hypothetical protein	NA	NA	NA	NA
WP_001898459.1\|355253_356213_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	2.3e-44	37.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053800

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP053801

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection