CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_CP053814	Vibrio cholerae strain W7G chromosome 2, complete sequence	1 crisprs	RT,csa3,cas3	0	0
NZ_CP053813	Vibrio cholerae strain W7G chromosome 1, complete sequence	2 crisprs	cas3,DEDDh,DinG,csx1,csa3	1	3
NZ_CP053815	Vibrio cholerae strain W7G plasmid pW7G, complete sequence	0 crisprs	DinG	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053813_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053813_1

2046111-2046406

Orphan

Consensus_repeat	Method
TGCGGTCGCCGCCGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAAC	PILER-CR

2 spacers

DEDDh

The CRISPR arrays of NZ_CP053813_1

>merge|NZ_CP053813|1|2046111-2046406|PILER-CR
GCCGTCGCTGCGGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAACCGAAAGCGCAGCTCAGCCAGCACAAGCCACGCCAAGCAGTGACGAGGCTGATCCGGAAAAAGCTGCGGTCGCCGACGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAACCAAAAGTACAGCTCAGCCAGCTCAAGCCACGCCAAGCAGTGACGAGGCTGACCCGAAAAAAGCTGCGGTCGCCGCCGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAAC

>NZ_CP053813|1|1|2046111-2046406|PILER-CR
GCCGTCGCTGCGGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAACC	GAAAGCGCAGCTCAGCCAGCACAAGCCACGCCAAGCAGTGACGAGGCTGATCCGGAAAAAGCT
GCGGTCGCCGACGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAACC	AAAAGTACAGCTCAGCCAGCTCAAGCCACGCCAAGCAGTGACGAGGCTGACCCGAAAAAAGCT
GCGGTCGCCGCCGCCATTGCTCGCGCTAAAGCGCGTAAAGCAGAGCAGCAGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053813.1\|WP_001057745.1\|2049204_2049846_+\|endonuclease-III	unknown	unknown	gnl\|CDD\|182661
NZ_CP053813.1\|WP_001045948.1\|2050950_2051835_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|375819
NZ_CP053813.1\|WP_001888250.1\|2038466_2039834_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NZ_CP053813.1\|WP_000954369.1\|2047854_2048484_+\|electron-transport-complex-subunit-RsxG	unknown	unknown	gnl\|CDD\|179350
NZ_CP053813.1\|WP_175246971.1\|2035947_2036937_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|234672
NZ_CP053813.1\|WP_095490387.1\|2052883_2054209_+\|Na+/H+-antiporter-family-protein	unknown	unknown	gnl\|CDD\|224967
NZ_CP053813.1\|WP_000863732.1\|2046796_2047843_+\|electron-transport-complex-subunit-RsxD	unknown	unknown	gnl\|CDD\|234844
NZ_CP053813.1\|WP_000598589.1\|2034643_2034889_-\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|182985
NZ_CP053813.1\|WP_001293888.1\|2048485_2049178_+\|electron-transport-complex-subunit-E	unknown	unknown	gnl\|CDD\|237091
NZ_CP053813.1\|WP_000029988.1\|2040263_2042294_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NZ_CP053813.1\|WP_000130224.1\|2052108_2052783_+\|ribonuclease-T	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|179951
NZ_CP053813.1\|WP_001021927.1\|2050464_2050902_+\|DUF2753-domain-containing-protein	unknown	unknown	gnl\|CDD\|287867
NZ_CP053813.1\|WP_000334237.1\|2054336_2055851_-\|amidophosphoribosyltransferase	unknown	unknown	gnl\|CDD\|236427
NZ_CP053813.1\|WP_002043588.1\|2034885_2035365_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP053813.1\|WP_000141550.1\|2043175_2043757_+\|electron-transport-complex-subunit-RsxA	unknown	unknown	gnl\|CDD\|235352
NZ_CP053813.1\|WP_000509705.1\|2035375_2035888_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|131715
NZ_CP053813.1\|WP_001209531.1\|2038121_2038463_-\|Hpt-domain-containing-protein	unknown	unknown	gnl\|CDD\|366732
NZ_CP053813.1\|WP_019829917.1\|2049886_2050303_+\|lactoylglutathione-lyase	unknown	unknown	gnl\|CDD\|272886
NZ_CP053813.1\|WP_000061070.1\|2037242_2038133_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NZ_CP053813.1\|WP_000104485.1\|2043756_2044344_+\|electron-transport-complex-subunit-RsxB	unknown	unknown	gnl\|CDD\|235347

Protein	Function_ID	Function_description	E-value
NZ_CP053813.1\|WP_001057745.1\|2049204_2049846_+\|endonuclease-III	gnl\|CDD\|182661	PRK10702, PRK10702, endonuclease III; Provisional.	2.13039e-145
NZ_CP053813.1\|WP_001045948.1\|2050950_2051835_-\|OmpA-family-protein	gnl\|CDD\|375819	pfam18393, MotY_N, MotY N-terminal domain. The bacterial flagellar motor is a rotary motor complex composed of various proteins. MotX and MotY are essential for the Na+-driven flagellar motor motility of Vibrio, Shewanella and Aeromonas species. MotY is main component for T-ring formation and absence of MotY completely disrupt the T-ring formation. This is the N-terminal domain of MotY which is shown to be essential for motility and responsible for the interaction with both MotX and the basal body. Functional analysis suggests that MotY-N connects the basal body to MotX and that the PomA/PomB complex associates with MotX to form the functional stator complex around the rotor. MotY-N alone does not associate strongly with the basal body, but the partial T-ring structure made of the MotY-N/MotX complex is sufficient to allow at least a few PomA/PomB stator complexes to be incorporated into the motor.	7.14257e-78
NZ_CP053813.1\|WP_001888250.1\|2038466_2039834_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NZ_CP053813.1\|WP_000954369.1\|2047854_2048484_+\|electron-transport-complex-subunit-RsxG	gnl\|CDD\|179350	PRK01908, PRK01908, electron transport complex protein RnfG; Validated.	7.08715e-127
NZ_CP053813.1\|WP_175246971.1\|2035947_2036937_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|234672	PRK00164, moaA, GTP 3',8-cyclase MoaA.	0
NZ_CP053813.1\|WP_095490387.1\|2052883_2054209_+\|Na+/H+-antiporter-family-protein	gnl\|CDD\|224967	COG2056, COG2056, Predicted permease [General function prediction only].	0
NZ_CP053813.1\|WP_000863732.1\|2046796_2047843_+\|electron-transport-complex-subunit-RsxD	gnl\|CDD\|234844	PRK00816, rnfD, electron transport complex protein RnfD; Reviewed.	0
NZ_CP053813.1\|WP_000598589.1\|2034643_2034889_-\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|182985	PRK11130, moaD, molybdopterin synthase small subunit; Provisional.	5.31902e-53
NZ_CP053813.1\|WP_001293888.1\|2048485_2049178_+\|electron-transport-complex-subunit-E	gnl\|CDD\|237091	PRK12405, PRK12405, electron transport complex RsxE subunit; Provisional.	3.98478e-134
NZ_CP053813.1\|WP_000029988.1\|2040263_2042294_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NZ_CP053813.1\|WP_000130224.1\|2052108_2052783_+\|ribonuclease-T	gnl\|CDD\|179951	PRK05168, PRK05168, ribonuclease T; Provisional.	1.46967e-161
NZ_CP053813.1\|WP_001021927.1\|2050464_2050902_+\|DUF2753-domain-containing-protein	gnl\|CDD\|287867	pfam10952, DUF2753, Protein of unknown function (DUF2753). This bacterial family of proteins has no known function.	3.52491e-95
NZ_CP053813.1\|WP_000334237.1\|2054336_2055851_-\|amidophosphoribosyltransferase	gnl\|CDD\|236427	PRK09246, PRK09246, amidophosphoribosyltransferase; Provisional.	0
NZ_CP053813.1\|WP_002043588.1\|2034885_2035365_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	5.67374e-105
NZ_CP053813.1\|WP_000141550.1\|2043175_2043757_+\|electron-transport-complex-subunit-RsxA	gnl\|CDD\|235352	PRK05151, PRK05151, electron transport complex protein RsxA; Provisional.	4.22504e-120
NZ_CP053813.1\|WP_000509705.1\|2035375_2035888_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|131715	TIGR02667, Molybdenum_cofactor_biosynthesis_protein_B., molybdenum cofactor biosynthesis protein B, proteobacterial. This model represents the MoaB protein molybdopterin biosynthesis regions in Proteobacteria. This crystallized but incompletely characterized protein is thought to be involved in, though not required for, early steps in molybdopterin biosynthesis. It may bind a molybdopterin precursor. A distinctive conserved motif PCN near the C-terminus helps distinguish this clade from other homologs, including sets of proteins designated MogA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	5.97413e-104
NZ_CP053813.1\|WP_001209531.1\|2038121_2038463_-\|Hpt-domain-containing-protein	gnl\|CDD\|366732	pfam01627, Hpt, Hpt domain. The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes. In S. cerevisiae ypd1p this domain has been shown to contain a binding surface for Ssk1p (response regulator receiver domain containing protein pfam00072).	2.89002e-08
NZ_CP053813.1\|WP_019829917.1\|2049886_2050303_+\|lactoylglutathione-lyase	gnl\|CDD\|272886	TIGR00068, Lactoylglutathione_lyase, lactoylglutathione lyase. Lactoylglutathione lyase is also known as aldoketomutase and glyoxalase I. Glyoxylase I is a homodimer in many species. In some eukaryotes, including yeasts and plants, the orthologous protein carries a tandem duplication, is twice as long, and hits this model twice. [Central intermediary metabolism, Amino sugars, Energy metabolism, Other].	1.82567e-80
NZ_CP053813.1\|WP_000061070.1\|2037242_2038133_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	2.20109e-151
NZ_CP053813.1\|WP_000104485.1\|2043756_2044344_+\|electron-transport-complex-subunit-RsxB	gnl\|CDD\|235347	PRK05113, PRK05113, electron transport complex protein RnfB; Provisional.	3.6166e-127

>NZ_CP053813.1|WP_000104485.1|2043756_2044344_+|electron-transport-complex-subunit-RsxB
MSTIVIAVIALAALAAVFGAILGFASIRFKVEADPIVDQIDAILPQTQCGQCGYPGCRPYAEAIANGDAINKCPPGGQATIEKLADLMGVEVQDSAHDLDDKVKMVAFIHEDMCIGCTKCIQACPVDAIVGGNKAVHTVIKNECTGCDLCVAPCPTDCIEMIPVQTTPESWKWQLNAIPVVNVTDSAPAAQKSAN
>NZ_CP053813.1|WP_000141550.1|2043175_2043757_+|electron-transport-complex-subunit-RsxA
MTEYLLLLIGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAYLVESYVLRPLGIEYLRTMSFILVIAVVVQFTEMVVHKTSPTLYRLLGIFLPLITTNCAVLGVALLNINENHNFIQSIIYGFGAAVGFSLVLILFASMRERIHVADVPAPFKGASIAMITAGLMSLAFMGFTGLVKL
>NZ_CP053813.1|WP_000029988.1|2040263_2042294_-|excinuclease-ABC-subunit-UvrB
MSKAFELVSDYQPAGDQPTAIKQLLEGLEAGLAHQTLLGVTGSGKTFTLANVIATAQRPTIILAPNKTLAAQLYGEMKAFFPNNAVEYFVSYYDYYQPEAYVPTTDTFIEKDASVNAHIEQMRLSATKALLERKDAVIVASVSAIYGLGDPDSYLKMMLHLRRGDVINQRDMLRRLAELQYSRNDMAFERGQFRVRGEVIDIFPAESDQEAVRVEMFDDEVECISLFDPLTGVITSRDLARFTIYPKTHYVTPRERILEAIEQIKSELQVRRQYLLDNNKLLEEQRISQRTQFDIEMMNELGFCSGIENYSRYLSGRAEGEPPPTLFDYLPHDGLLIIDESHVTVPQIGAMFKGDRSRKETLVEFGFRLPSALDNRPLKFDEFEALAPQTIFVSATPSEYELTKSGGEVAEQVVRPTGLLDPIIEVRPVATQVDDLLSEARIRAANDERILVTTLTKRMAEDLTEYLHEHGVKVRYLHSDIDTVERVEIIRDLRLGVFDVLVGINLLREGLDMPEVALVAILDADKEGFLRSERSLIQTMGRAARNVNGKAILYADSITKSMRKAIDETERRREKQLAYNEQRGITPQPLKRSVKDIMELGDIAKSRKQKNSKVVPLAKVAEESAAYQVLTPQQLEKEISKLEAAMYQHAQNLEFELAAQKRDEIHQLRQQFIANS
>NZ_CP053813.1|WP_001888250.1|2038466_2039834_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MVEDTASVAALYRSYLTPLDIDINIVGTGRDAIESIGRREPDLILLDLRLPDMTGMDVLYAVKEKSPDVPIVFMTAHGSIDTAVEAMRHGAQDFLIKPCEADRLRVTVNNAIRKASKLKNDVDNKNQNYQGFIGSSQTMQAVYRTIDSAASSKASIFITGESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAATERQGAAEAADGGTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRARGDDVIEIAYSLLGFMSKEEGKDFVRLSAEVVERFRQYEWPGNVRQLQNVLRNVVVLNEGREITLDMLPPPLNQMSAPINRALPLAHENKVSVHEIFPLWMTEKQAIEQAIEACDGNIPRAATYLDVSPSTIYRKLQTWNEKVKEKEKER
>NZ_CP053813.1|WP_001209531.1|2038121_2038463_-|Hpt-domain-containing-protein
MREWINQSKIDLLAKEIGEENVPILVNIFLGELNDYQSKLVSDTVADKLGYLKEISHALKSSAASFGADRLCAKAVELDSRAKSGEMMDISLEVEHMLELLKQTHQCYSDLVH
>NZ_CP053813.1|WP_000061070.1|2037242_2038133_+|YvcK-family-protein
MSLYENKKVVAIGGGHGLGRMLAALKVFGSNATGIVTTTDNGGSTGRIRHCQGGIAWGDTRNCINQLITEPSISSMMFEYRFKGAGELNGHNLGNLMLTALDNLSVRPLDAINLIRNMLKVDVNILPMSEHPSDLAALAMDGKWVTGETSVDEMTQDLRRLDLAPEVPATKEAVTAIQDADCVILGPGSFLTSVMPPLLLPELGKAIARNQTAKVIFVENLSPEYGPAGRMSLEQKLEWCERACQGRKIDVVLGHHPHPELEQRWNFVTRDLASANRDWRHDRQKLRQAIEEQLMN
>NZ_CP053813.1|WP_175246971.1|2035947_2036937_-|GTP-3',8-cyclase-MoaA
MAQQFEDRFQRKFYYLRLSITDVCNFKCTYCLPDGYKPSADRPASFLTVNEIRRVVSAFAHCGTSKVRITGGEPSLRKDFGEIIHTIAQTPGIQKVATTTNGYRLAKHIGEWREAGLTQLNVSVDSLDPRMFAQITGENRFQQVMSGIDRAFEVGFEQVKVNVVLMKNLNHLELPKFMAWIKTRPIQLRFIELMQTGEMDALFARLHVSGISIRDYLLGNGWLLKARADNDGPAQVFIHPDFQGEIGLIMPYEKDFCRSCNRLRVSALGKLHLCLFGEQGIELRDLLQDDHQENALIERIQTQLQNKAETHFLHDGNSGVTPHLASIGG
>NZ_CP053813.1|WP_000509705.1|2035375_2035888_-|molybdenum-cofactor-biosynthesis-protein-B
MGHAESKFQAANIAVLTVSDTRTEENDTSGRYLAEQLQEAGHTLADKQIVIDDMYKIRAVVSQWIADETIQAILITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRMVSFEEIGTSTIQSRAVAGFANHTVIFAMPGSTGACRTGWTKIIKQQLDASHRPCNFMPHLTV
>NZ_CP053813.1|WP_002043588.1|2034885_2035365_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MSQLTHINASGEANMVDVSNKADTVREARAEAYVRMAPETLQLILSGQHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLEALLEQNSVRIESLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIENVRLLEKLGGKSGHFKVDA
>NZ_CP053813.1|WP_000598589.1|2034643_2034889_-|molybdopterin-synthase-sulfur-carrier-subunit
MIKVLFFAQTRELVECDSLVVDHAFATVEALRQHLAQQPGKWDMALEPGKLLAAVNQSIVPFDTELNDGDEVAFFPPVTGG
>NZ_CP053813.1|WP_000863732.1|2046796_2047843_+|electron-transport-complex-subunit-RsxD
MAFFIASSPHLRSKRSTADVMRWVLACALPGLIAQTYFFGYGTLIQLLLAISVAVALEAGIMLLRKRSPISALRDYSAVVTAWLLAVAIPPLSPWWVVVIGLIFAIVIAKHLYGGLGQNPFNPAMIAYVVLLISFPVQMTSWMAPIKLTAEPSSLVDSFSLIFGGFDSDGLSLQQIRTGIDGITMATPLDAIKTSLKAGHTMSETLTQPQFSGFAGIGWEWVNIAYLLGGLILLKLRIIRWHIPMAMLAGLVFTALLAQLFAPGTTASPMIHLLSGATMLGAFFIATDPVSASTTDKGRLIYGFFIGAMVFLIRSWGGFPDGVAFAVLLANMCVPLIDYYTKPRTYGH
>NZ_CP053813.1|WP_000954369.1|2047854_2048484_+|electron-transport-complex-subunit-RsxG
MLTAIRKNGLILAVFACVSTGLVALTYALTAEQIQQQEQKQLLQVLNQVIPHKYHDNPLAQACTLVNDDKLGTAKTMHAYLAQRDGQPTAIAVETIAPDGYNGEIKLIVGIANNGTVLGVRVLAHQETPGLGDKIDLRISNWVLGFNGQQVTADNQDDWKVRKDGGQFDQFTGATITPRAVVLAVKKAVEYVNQHQQQLHNQPNPCEGQ
>NZ_CP053813.1|WP_001293888.1|2048485_2049178_+|electron-transport-complex-subunit-E
MSENRTLMLNGMWNNNPALVQLLGLCPLLAVSSTVTNALGLGIATLLVLVGSNVTVSLVRDYVPKEVRIPVFVMIIASLVTCVQLLMNAYAYGLYLSLGIFIPLIVTNCIIIGRAEAFASKNDVLPAALDGFWMGLGMTSVLVVLGSLREIIGNGTLFDGADLLLGEWAKVLRIEVFHFDSAFLLALLPPGAFIGVGFLIAAKSVIDKQIAARQPKQQKQAIERARVTNV
>NZ_CP053813.1|WP_001057745.1|2049204_2049846_+|endonuclease-III
MNNAKRIEILERLRANNPKPETELNWNSPFELLIAVLLSAQATDVSVNKATDKLYAVANTPQAMLDLGVDGVKEYIKTIGLFNSKAENVIKTCRILLEKHQGEVPEDREALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVSNRTKFAVGKNVDEVEHKLLKVVPNEFKLDVHHWLILHGRYTCVARKPRCGSCIIEDLCEFKDKVYPES
>NZ_CP053813.1|WP_019829917.1|2049886_2050303_+|lactoylglutathione-lyase
MSNHRILHTMLRVGDLDKSIEFYTQVMGMSLLRKNENTEYKYTLAFLGYGDESQGAVIELTYNWGVADYEKGNAFGHIAIGVDDIYATCDTIKAAGGIVTREPGPVKGGTTHIAFVKDPDGYMIELIQNKQAHAGLEG
>NZ_CP053813.1|WP_001021927.1|2050464_2050902_+|DUF2753-domain-containing-protein
MNIKEWERHTLLADIAMQESDHLRSILHYQQALTVSQQLDESEEIDMEDRMMISVISCHNMAKFWRTMGDNQYELKYLQLASERVLTLIPQCHKPGCEAFVDSLGCCRKALLDFMKRHPNPEIARMVQHIDTASKCEIIAQFRLN
>NZ_CP053813.1|WP_001045948.1|2050950_2051835_-|OmpA-family-protein
MNKWVITSLFAISTLSASVASALEVRYVATPQQSTWQMATNTPLECRLVHPIPNYGDAEFSSRAGKKINLDFELKMRRPMGDTRNVSLVSMPPVWRPGEGADRITNLQFFKQFDGYIGGQTAWSLLSELEKGRYPTFSYQDWQSRDQRIEVALSSVLFQQPYNEFSDCISKLLPYSFEDISFTILHYDQGTSVELNKASQKRLAQIAEYVRYNQDIDLVLVSTYTDSTDTNNNSQNLSEQRAEVLREYFKSIGLPEDRIQVQGYGKRRPIADNASPIGKDKNRRVVISLGRTQV
>NZ_CP053813.1|WP_000130224.1|2052108_2052783_+|ribonuclease-T
MTDKNDALTLKKRFRGYFPVVIDVETAGFNAQTDALLEICAVTLSMDENGDLHPASTIHFHVEPFEGANLEKAALEFTGIYDPFSPLRGAVSEDHALKEIYKLVRKEQKAADCSRAIIVAHNAHFDHSFVMAASERCKLKRVPFHPFATFDTATLSGLAFGQTVLAKACKTAGMEFDNREAHSALYDTQKTAELFCTIVNQWKALGGWPLVNDDEDNNNDADLN
>NZ_CP053813.1|WP_095490387.1|2052883_2054209_+|Na+/H+-antiporter-family-protein
MNPVVISVCVMLLLALMRVNVVVALTFSAVVGGLVAGMSLNETVAAFESGLGGGATIALSYAMLGTFAVAISKSGITDLLAQSVIRRIHGQESHAASTGLKYLVLISLLLMAVASQNVIPVHIAFIPILIPPLLSVFAKLKLDRRLVACVLTFGLITPYMVLPVGFGGIFLNNILLKNLHENGLESITASQVPTAMILPAAGMIFGLLLAVLFSYRKPREYQETKLTVVQQESSSINKQHIAIAGVGIVAALAVQLLTGSMIIGALAGFMVFTFGGVIAWKETHDVFTRGVHMMAMIGFIMISAAGFAAVMKATGGVETLVTSLSTSIGDNKALAALLMLVVGLLVTMGIGSSFSTIPIIATIYVPLCLSFGFSPMATVALVGTAAALGDAGSPASDSTLGPTSGLNADGQHEHIWETVVPTFIHYNLPLIVFGWIAAMVL
>NZ_CP053813.1|WP_000334237.1|2054336_2055851_-|amidophosphoribosyltransferase
MCGIVGIVGTTPVNQSIYDALTVLQHRGQDAAGICTIESNRFRLRKANGLVRDVFEAKHMQRLQGNVGIGHVRYPTAGSSSASEAQPFYVNSPFGITLAHNGNLTNANQVRQKLFEKDRRHVNTTSDSEVLLNVLAHEIDTVKGNVTAEDVFRAISNVHRTIRGAYAVAAMIIGHGMIAFRDPHGIRPLCLGKREVNGQLEYMVASESVALDAVGFDFVRDVAPGEAIYATFDGELYTKQCADNPALNPCIFEFVYFARPDSFIDKISVYSARVEMGKRLGERIKNDYSDLDIDVVIPIPETSCDIALQIAQAIDKPYRQGFVKNRYVGRTFIMPGQQQRKKSVRRKLNAIRSEFKDKNVLLVDDSIVRGTTSEQIIEMARDSGAKKVYIVSAAPEIRFPNVYGIDMPSANELIAHGRDNDAICKQIGADALIFQTLEDLVEAVRCGNPDIVKFEASVFNGEYVTGDIDQQYLDFLESMRSDDAKVQREIQQDLANLELHNEGA

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Crispr_ID: NZ_CP053813_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053813_2

2598382-2598625

Orphan

Consensus_repeat	Method
AAAATGTGCCTCCTTAGCTCAGTCGGTAGAGCAACGGACTGATAATCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP053813_2

>merge|NZ_CP053813|2|2598382-2598625|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAATTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAATTGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

>NZ_CP053813|2|2|2598382-2598625|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGG	TCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAA
TTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTG	TCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAAT
TGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053813.1\|WP_000805054.1\|2593584_2594505_-\|glutaminase-B	unknown	unknown	gnl\|CDD\|234880
NZ_CP053813.1\|WP_001233674.1\|2591279_2591711_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616
NZ_CP053813.1\|WP_001230176.1\|2597023_2598151_+\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
NZ_CP053813.1\|WP_044126934.1\|2602600_2604952_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP053813.1\|WP_175247019.1\|2598916_2600542_+\|cache-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP053813.1\|WP_000725022.1\|2591780_2592383_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP053813.1\|WP_057550646.1\|2590386_2590944_+\|YggT-family-protein	unknown	unknown	gnl\|CDD\|223833
NZ_CP053813.1\|WP_000780521.1\|2605004_2606300_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP053813.1\|WP_000954094.1\|2610042_2610516_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|182143
NZ_CP053813.1\|WP_000546924.1\|2601587_2602442_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP053813.1\|WP_000124738.1\|2596649_2596922_+\|oxidative-damage-protection-protein	unknown	unknown	gnl\|CDD\|180059
NZ_CP053813.1\|WP_033933170.1\|2595574_2596636_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|182805
NZ_CP053813.1\|WP_000957330.1\|2592376_2593552_+\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550
NZ_CP053813.1\|WP_057563351.1\|2607295_2608111_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP053813.1\|WP_000005581.1\|2594615_2595335_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP053813.1\|WP_000035022.1\|2608573_2609383_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|234673
NZ_CP053813.1\|WP_000383338.1\|2608182_2608563_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP053813.1\|WP_000741915.1\|2590943_2591234_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP053813.1\|WP_000973540.1\|2609532_2610030_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_CP053813.1\|WP_000095776.1\|2606289_2607282_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696

Protein	Function_ID	Function_description	E-value
NZ_CP053813.1\|WP_000805054.1\|2593584_2594505_-\|glutaminase-B	gnl\|CDD\|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
NZ_CP053813.1\|WP_001233674.1\|2591279_2591711_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	6.80534e-67
NZ_CP053813.1\|WP_001230176.1\|2597023_2598151_+\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	9.42926e-157
NZ_CP053813.1\|WP_044126934.1\|2602600_2604952_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP053813.1\|WP_175247019.1\|2598916_2600542_+\|cache-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	2.89438e-58
NZ_CP053813.1\|WP_000725022.1\|2591780_2592383_+\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	6.3348e-128
NZ_CP053813.1\|WP_057550646.1\|2590386_2590944_+\|YggT-family-protein	gnl\|CDD\|223833	COG0762, COG0762, Predicted integral membrane protein [Function unknown].	2.45272e-12
NZ_CP053813.1\|WP_000780521.1\|2605004_2606300_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	9.14533e-157
NZ_CP053813.1\|WP_000954094.1\|2610042_2610516_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|182143	PRK09917, PRK09917, threonine/serine exporter.	7.58394e-67
NZ_CP053813.1\|WP_000546924.1\|2601587_2602442_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.60415e-153
NZ_CP053813.1\|WP_000124738.1\|2596649_2596922_+\|oxidative-damage-protection-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	5.47988e-59
NZ_CP053813.1\|WP_033933170.1\|2595574_2596636_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP053813.1\|WP_000957330.1\|2592376_2593552_+\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
NZ_CP053813.1\|WP_057563351.1\|2607295_2608111_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.44232e-146
NZ_CP053813.1\|WP_000005581.1\|2594615_2595335_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.57395e-111
NZ_CP053813.1\|WP_000035022.1\|2608573_2609383_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|234673	PRK00166, apaH, symmetrical bis(5'-nucleosyl)-tetraphosphatase.	5.07117e-169
NZ_CP053813.1\|WP_000383338.1\|2608182_2608563_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	1.16069e-74
NZ_CP053813.1\|WP_000741915.1\|2590943_2591234_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	9.17224e-61
NZ_CP053813.1\|WP_000973540.1\|2609532_2610030_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	1.05107e-92
NZ_CP053813.1\|WP_000095776.1\|2606289_2607282_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0

>NZ_CP053813.1|WP_001230176.1|2597023_2598151_+|membrane-bound-lytic-murein-transglycosylase-MltC
MRKLVLCITALLLSGCSREFIEKIYDVDYEPTNRFAKNLAELPGQFQKDTAALDALINSFSGNIEKRWGRRELKIAGKNNYVKYIDNYLSRSEVNFTEGRIIVETVSPIDPKAHLRNAIITTLLTPDDPAHVDLFSSKDIELKGQPFLYQQVLDQDGQPIQWSWRANRYADYLIANHLKVKQVDFKKAYYVEIPMVKDQIDIRGYKYASIVRKASRKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKNRSGEPSPEYLFNPENNIDTGTAYFYILKNRYLKEVRHPTSLEYSMISAYNGGTGGVLSTFSSDRQRAMRDLNALQPNQVYWALTKKHPNAEARRYLEKVTKFKKEFNAG
>NZ_CP053813.1|WP_000124738.1|2596649_2596922_+|oxidative-damage-protection-protein
MARTVFCTRLQKEADGLDFQLYPGELGKRIFDNICKEAWAQWQTKQTMLINEKKLNMMDPEHRKLLEQEMVNFLFEGKEVHIEGYTPPAK
>NZ_CP053813.1|WP_033933170.1|2595574_2596636_+|A/G-specific-adenine-glycosylase
MTPFAQAILTWYDAYGRKNLPWQQNKNAYRVWLSEIMLQQTQVATVIPYFERFLERFPTVQALAAAPQDEVLHFWTGLGYYARARNLHKAAKMVVSEYGGEFPTDLEQMNALPGVGRSTAAAVLSSVYKKPHAILDGNVKRTLARCFAVQGWPGQKSVENQLWHYAEMHTPKVDVDKYNQAMMDMGAMICTRSKPKCSLCPVESFCLAKQQGNPQEYPGKKPKTDKPVKATWFVMLYHDNAVWLEQRPQSGIWGGLYCFPQSEIANIQTTIDQRAIGDSTITSQKTLIAFRHTFSHYHLDITPILLQLSRKPDIVMEGSKGLWYNLSQPDEIGLAAPVKQLLHSLPFDIDSHI
>NZ_CP053813.1|WP_000005581.1|2594615_2595335_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVITQEYTEDGKVLRRIRSFVRREGRLTKGQEAAMKECWPTMGIDYQPELLDWQQVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHDAVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLIIGSGVFHMATDWENYAEHMIEVMNQAPGFANLATDGDYIPRPDERPLTKFEQRGHRLGHGVWDIKYQRTA
>NZ_CP053813.1|WP_000805054.1|2593584_2594505_-|glutaminase-B
MKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVISAGDAQEGFSIQSISKVLSLTLAMGLYQPDELWSRVGKEPSGQAFNSLIQLEMEQGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIAYDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSKQTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF
>NZ_CP053813.1|WP_000957330.1|2592376_2593552_+|radical-SAM-family-heme-chaperone-HemW
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGDIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEGIARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAQLAHKIGLNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQYEISGYSKPSYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSELLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWAISEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE
>NZ_CP053813.1|WP_000725022.1|2591780_2592383_+|XTP/dITP-diphosphatase
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEVAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLAAMQDVPNDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTSPHGSNGFGYDPIFWVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRTC
>NZ_CP053813.1|WP_001233674.1|2591279_2591711_+|DUF4426-domain-containing-protein
MRKWMMSLLLTLLALPASAEQQKTIKDIEVHYSAFNSTFLTPKVASSYQLTRNGYTAILNISVLDRASLGKPATEAKLTGHAKNLIGNLRELSFKQVKEGNAIYYLAEVPISNEEMLTFDIDVDAGLKGAGKLTFSQKFYTEQ
>NZ_CP053813.1|WP_000741915.1|2590943_2591234_+|YggU-family-protein
MAAVWREGDDLLLRLYIQPKASRDSIVGLHGEELKVAITAPPIDGKANAHLSKYLAKLCKVAKGSVVIEKGELGRHKQVRILQPSQIPAEITALIE
>NZ_CP053813.1|WP_057550646.1|2590386_2590944_+|YggT-family-protein
MNSLSFLINTLFDLYIMVVILRIWLQAARADFYNPFSQFIVKATQPVVGPLRRVIPSIGSIDLATIVFAYVLCVLKFMALVLIASNGSVSFSADFLFLGLLSLIKAAGGLLFWVLLIRAILSWVSQGRSPIEYVFHQLTEPMLAPIRRIIPVMGGFDLSILVLFIVLQFANFLMGDVIGPIWYQL
>NZ_CP053813.1|WP_175247019.1|2598916_2600542_+|cache-domain-containing-protein
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFAIQAPKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDNQQQSTAMIATAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVNNIQGLATQLQTASTAVADLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQIATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR
>NZ_CP053813.1|WP_000546924.1|2601587_2602442_-|co-chaperone-DjlA
MHIFGKILGAFFGFLFGGPFGAIFGIFLGHQFDKARRLNQAGFQSGTFGAGPSQAERQEEFFKSAFSVMGHVAKAKGQVTKEEIQLATIMMDRMNLTLEQKRAAQDAFRDGKESDFPLEQVLERVKIATGGRFDLLQFFLELQVSSAFADGDVHPSERQVLHRIARGLGFSSEQLERRLRMQEAAFRFQQGGGFGGSQQQSHSGQQWQQPSSRHQLADAYEVLGVSESASAQEVKRAYRKLMNEHHPDKLMAKGLPPEMMNVAKEKSQQIQHAYELIRKEKGIK
>NZ_CP053813.1|WP_044126934.1|2602600_2604952_+|LPS-assembly-protein-LptD
MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLADDQLHTELGDRWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSDLDSGVGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTKDTTSTNLPYRLMPQLSYNYYAPETMKYLDLDLVSHISRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVTRVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTLLQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNKNPDSTSDKTSYSAWAVEMDFNFADYLFYHGGIQYDIDSQAVQLGNSTLEYRVASGYIQANYRYVAKDYIRNTVGDSITNIDDITRDGISQAGILAGYQLSRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFTYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
>NZ_CP053813.1|WP_000780521.1|2605004_2606300_+|peptidylprolyl-isomerase-SurA
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISHIQLRVDDGQDKSAAETLANKLVNDLKNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPTIFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILFNRKFNEEASAWLQELRASAFVEVLKDEKDEQ
>NZ_CP053813.1|WP_000095776.1|2606289_2607282_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSSKRIIVTAGEPAGIGPDLVLALSAQDWPHQLVVCADKALLAQRAVQLGIQVKLLDYQRDNPVQAQQAGTLLVEHIPLAEPVVAGQLNPANGHYVLKTLERAAKGCMNGEFDAIVTGPVHKGVINRAGVAFSGHTEFFAEQSKTPLVVMMLATEGLRTALVTTHLPLAEVPQAITCERLEQIVHILHKDLVEKFAIAEPKIYVCGLNPHAGEDGVLGMEEIETITPTLQRLREQYGMQLVGPLPADTIFSEKYLQQADAVLGMYHDQVLPVLKYKGFGRSVNITLGLPFIRTSVDHGTALDLAGTGQADAGSFWTALAYAIELVDKKAQ
>NZ_CP053813.1|WP_057563351.1|2607295_2608111_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MRNDVHLGHKARKRFGQNFLNDPYIIDGIVSAINPKPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELASKLTIHEGDAMRFDFKQLVRPNNKLRVFGNLPYNISTPLMFHLFEFHRDIQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYYCKVVPVLEVPPSAFVPPPKVDSAVVRLVPYEDLPHPATSLEWLDRVVREGFNQRRKTVRNCYKGLAEPETLETLGINPGMRPENLTLAQFVALANWLDATHKTHA
>NZ_CP053813.1|WP_000383338.1|2608182_2608563_+|Co2+/Mg2+-efflux-protein-ApaG
MDVSLPCIKIQVQTRYIEEQSNPEYQRFVFAYLITIKNLSSQTVQLMSRRWLITDADGKQTVVEGDGVVGEQPRIKANDEYTYSSGTALDTPVGVMQGQYLMIDEQGESFTVEIEPFRLAVPHVLN
>NZ_CP053813.1|WP_000035022.1|2608573_2609383_+|symmetrical-bis(5'-nucleosyl)-tetraphosphatase
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFAYQLGDAARVVLGNHDLHLLSVALGHHSAKRRDQTQAILDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIGLDTGCVWGGTLTMLRWEDKHYFSQAALPA
>NZ_CP053813.1|WP_000973540.1|2609532_2610030_-|type-3-dihydrofolate-reductase
MMISMIAAMADQRIIGKDNQMPWHLPADFAWFKRCTLGKPVVMGRKTYQSIGRPLPGRHNIVISRDASLQIEGVDVVTSIEAALAKAGEVDEVMIIGGGSLYAACLPMAHKLYITEIHAKLEGDTQFPEWGSDWLERSREHYPADEKNAYGMDFVIFERQNPLPT
>NZ_CP053813.1|WP_000954094.1|2610042_2610516_-|threonine/serine-exporter-family-protein
MLSWELFFGLLNDMFFAAIPAVGFALVFNVPVPALKYCALGGALGHGSRYLMMHFGVPIEWASFFAATLVGMVGVYWSRRFLAHPKVFTVAALIPMVPGVFAFKAMIALVEINHVGFSPELMEALLENFLKAMFIIAGLAVGLAVPGLLFYRRKPII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053813_2	2.1\|2598431\|37\|NZ_CP053813\|PILER-CR	2598431-2598467	37	NC_049942	Escherichia phage JLK-2012, complete sequence	23524-23560	4	0.892
NZ_CP053813_2	2.1\|2598431\|37\|NZ_CP053813\|PILER-CR	2598431-2598467	37	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35428-35464	4	0.892

1. spacer 2.1|2598431|37|NZ_CP053813|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
caggtcgccagttcgattccggtagccggcaccatat	Protospacer
.*********************.***********. *

2. spacer 2.1|2598431|37|NZ_CP053813|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
taggtcaccagttcgattccggtagccggcaccaatc	Protospacer
******.***************.*********** *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

653332 : 659949

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000210573.1\|653332_654466_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4
WP_175247072.1\|654477_655728_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-99	49.0
WP_000543544.1\|655827_656277_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_094392063.1\|656302_657406_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.5e-44	33.3
WP_000493874.1\|657410_658064_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001122865.1\|658104_659214_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000864130.1\|659478_659949_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7

DBSCAN-SWA_2

1570306 : 1593396

Vibrio_phage(76.92%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175246905.1\|1570306_1570489_-	hypothetical protein	Q64EU9	Vibrio_phage	5.7e-13	73.7
WP_114807526.1\|1570499_1571870_-	toxin	Q64EV0	Vibrio_phage	7.0e-204	79.2
WP_001160097.1\|1571872_1572217_-	DUF2523 domain-containing protein	Q64EV1	Vibrio_phage	1.0e-55	90.4
WP_175246906.1\|1572216_1573635_-	hypothetical protein	G8IRU9	Vibrio_phage	7.4e-132	67.1
WP_175246907.1\|1573767_1573977_-	hypothetical protein	G8IRU8	Vibrio_phage	3.6e-11	55.1
WP_000063788.1\|1574010_1574241_-	hypothetical protein	G8IRU7	Vibrio_phage	4.7e-28	76.0
WP_001284208.1\|1574250_1574589_-	DUF1293 domain-containing protein	Q858R2	Vibrio_phage	4.6e-56	97.3
WP_001112199.1\|1574588_1575698_-	replication initiation factor domain-containing protein	Q8W6E3	Vibrio_phage	2.9e-208	94.2
WP_000502183.1\|1575687_1575891_-	hypothetical protein	E1CJD3	Vibrio_phage	2.7e-35	100.0
WP_001018566.1\|1575901_1576150_-	hypothetical protein	O56843	Vibrio_virus	6.6e-20	61.0
WP_175230379.1\|1576328_1576685_+	regulator	Q9MCC3	Vibrio_phage	7.5e-33	58.7
WP_175246908.1\|1576936_1590007_-	MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA	B3Y8K3	Vibrio_virus	8.1e-07	100.0
WP_057552386.1\|1590030_1590492_-	RTX toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
WP_001906284.1\|1590517_1590865_-	hypothetical protein	NA	NA	NA	NA
WP_175247085.1\|1591290_1593396_+	RTX toxin T1SS ABC transporter subunit RtxB	W8CYL7	Bacillus_phage	4.9e-39	27.1

DBSCAN-SWA_3

2537797 : 2545022

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175247016.1\|2537797_2538685_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	1.1e-56	41.4
WP_001892042.1\|2538952_2541541_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_000116739.1\|2541634_2542642_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_000177559.1\|2542715_2543651_-	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000002982.1\|2543650_2544277_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000698379.1\|2544269_2545022_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP053814

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053814_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053814_1

757363-757498

Orphan

Consensus_repeat	Method
CCTCCCCCTTCTAGGGGGAGGTTGGGTGGGGGTATTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053814_1

>merge|NZ_CP053814|1|757363-757498|CRISPRCasFinder
CCTCCCCCTTCTAGGGGGAGGTTGGGTGGGGGTATTTCACGCCAGAGGAGTTAAACGTGGAAAATAAATACTTCAACAAAACTCAAATGTTTCACGCTCCTCCCCCTTCTAGGGGGAGGTTGGGAGGGGGTATTTC

>NZ_CP053814|1|1|757363-757498|CRISPRCasFinder
CCTCCCCCTTCTAGGGGGAGGTTGGGTGGGGGTATTTC	ACGCCAGAGGAGTTAAACGTGGAAAATAAATACTTCAACAAAACTCAAATGTTTCACGCT
CCTCCCCCTTCTAGGGGGAGGTTGGGAGGGGGTATTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053814.1\|WP_175247253.1\|754810_755569_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|223797
NZ_CP053814.1\|WP_175247252.1\|752997_754098_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	unknown	unknown	gnl\|CDD\|182993
NZ_CP053814.1\|WP_001960506.1\|754111_754807_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NZ_CP053814.1\|WP_001161566.1\|750199_750745_-\|heme-NO-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|377902
NZ_CP053814.1\|WP_001068418.1\|751052_751214_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_175247255.1\|762813_763335_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_175247256.1\|765907_767893_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NZ_CP053814.1\|WP_108335373.1\|760582_761317_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_142566859.1\|763705_764680_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NZ_CP053814.1\|WP_148527891.1\|758297_760586_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|350679
NZ_CP053814.1\|WP_175247254.1\|762174_762573_+\|YgiW/YdeI-family-stress-tolerance-OB-fold-protein	unknown	unknown	gnl\|CDD\|225653
NZ_CP053814.1\|WP_071180508.1\|749255_750203_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|236901
NZ_CP053814.1\|WP_001889103.1\|751270_751561_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_148527892.1\|757780_758227_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_001913462.1\|747080_749246_+\|TIGR01666-family-membrane-protein	unknown	unknown	gnl\|CDD\|130727
NZ_CP053814.1\|WP_170826482.1\|761660_761918_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053814.1\|WP_001147209.1\|764836_765808_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NZ_CP053814.1\|WP_032476864.1\|755579_757034_-\|cobyric-acid-synthase	unknown	unknown	gnl\|CDD\|234838
NZ_CP053814.1\|WP_001125116.1\|751647_752901_+\|hydroxymethylglutaryl-CoA-reductase	unknown	unknown	gnl\|CDD\|153081
NZ_CP053814.1\|WP_000009951.1\|767897_769163_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341038

Protein	Function_ID	Function_description	E-value
NZ_CP053814.1\|WP_175247253.1\|754810_755569_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|223797	COG0725, ModA, ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism].	3.35327e-80
NZ_CP053814.1\|WP_175247252.1\|752997_754098_-\|molybdenum-ABC-transporter-ATP-binding-protein-ModC	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
NZ_CP053814.1\|WP_001960506.1\|754111_754807_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	1.30776e-141
NZ_CP053814.1\|WP_001161566.1\|750199_750745_-\|heme-NO-binding-domain-containing-protein	gnl\|CDD\|377902	pfam07700, HNOB, Haem-NO-binding. The HNOB (Haem NO Binding) domain, is a predominantly alpha-helical domain and binds heme via a covalent linkage to histidine. It is a haem protein sensor (SONO) that displays femtomolar affinity for nitrous oxide, NO. It is predicted to function as a haem-dependent sensor for gaseous ligands and to transduce diverse downstream signals in both bacteria and animals.	2.84874e-43
NZ_CP053814.1\|WP_001147209.1\|764836_765808_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	3.68703e-31
NZ_CP053814.1\|WP_175247256.1\|765907_767893_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.34848e-64
NZ_CP053814.1\|WP_175247254.1\|762174_762573_+\|YgiW/YdeI-family-stress-tolerance-OB-fold-protein	gnl\|CDD\|225653	COG3111, COG3111, Periplasmic protein with OB-fold [Function unknown].	1.8995e-46
NZ_CP053814.1\|WP_148527891.1\|758297_760586_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|350679	cd17921, DEXHc_Ski2, DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins. Ski2-like RNA helicases play an important role in RNA degradation, processing, and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	3.09323e-22
NZ_CP053814.1\|WP_071180508.1\|749255_750203_-\|histidine-kinase	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	8.97269e-46
NZ_CP053814.1\|WP_142566859.1\|763705_764680_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	4.22454e-31
NZ_CP053814.1\|WP_001913462.1\|747080_749246_+\|TIGR01666-family-membrane-protein	gnl\|CDD\|130727	TIGR01666, Uncharacterized_protein_HI_1680, TIGR01666 family membrane protein. This model represents a clade of sequences from gamma and beta proteobacteria. These proteins are >700 amino acids long and many have been annotated as putative membrane proteins. The gene from Salmonella has been annotated as a putative efflux transporter. The gene from E. coli has the name yccS. [Cell envelope, Other].	0
NZ_CP053814.1\|WP_032476864.1\|755579_757034_-\|cobyric-acid-synthase	gnl\|CDD\|234838	PRK00784, PRK00784, cobyric acid synthase.	0
NZ_CP053814.1\|WP_001125116.1\|751647_752901_+\|hydroxymethylglutaryl-CoA-reductase	gnl\|CDD\|153081	cd00643, HMG-CoA_reductase_classI, Class I hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class I enzyme, homotetramer. Catalyzes the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. In mammals this is the rate limiting committed step in cholesterol biosynthesis. Class I enzymes are found predominantly in eukaryotes and contain N-terminal membrane regions. With the exception of Archaeoglobus fulgidus, most archeae are assigned to class I, based on sequence similarity of the active site, even though they lack membrane regions. Yeast and human HMGR are divergent in their N-terminal regions, but are conserved in their active site. In contrast, human and bacterial HMGR differ in their active site architecture.	3.1596e-176
NZ_CP053814.1\|WP_000009951.1\|767897_769163_+\|MFS-transporter	gnl\|CDD\|341038	cd17485, MFS_MFSD3, Major facilitator superfamily domain containing 3 protein. Major facilitator superfamily domain containing 3 protein (MFSD3) is a predicted acetyl-CoA transporter. As an atypical putative membrane-bound solute carrier (SLC), MFSD3 is most likely to be functionally active in the plasma membrane and not in any intracellular organelles. MFSD3 belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.13816e-68

>NZ_CP053814.1|WP_032476864.1|755579_757034_-|cobyric-acid-synthase
MKKWLMVQGTTSDAGKSVLVAGLCRVLARRGIQVCPFKPQNMALNSAVTPDGGEIGRAQAVQAQACGIAPSVHMNPVLLKPNSDTGAQVILQGRALSNMEANAYHDYKKVAMDTVMDSFQRLQQEYEAIMIEGAGSPAEINLRENDIANMGFAEKADVPVIIVADIDRGGVFAHLYGTLALLSESEQARVKGFVINRFRGDIGLLQSGLDWLEQKTGKPVIGVLPYLHGFDLEAEDAIAAQQNLSADRQLRVAVPVFTRISNHTDFDPLRLNPNIDFRYVGQGESLSGADLIILPGSKSTRADLAYLRSQGWDKEILRHLRLGGKVMGICGGFQMLGEWVHDPLGIEGEAGSSEGLGLFAMQTELTAEKRLTNVQGHLTLDGQTVAAQGYEIHAGRSSWAADQKSPIILSDGSLDGLVSDCNQGFGTYLHGIFDRPETALRICQWAGAKEIEAYDHRAAQERAIDRIADAIEQHLDLSLLWPDL
>NZ_CP053814.1|WP_175247253.1|754810_755569_-|molybdate-ABC-transporter-substrate-binding-protein
MLTRILLLLCVALNAPLASAKETLHIYAASSMTNAVNALVADYSQQHDVKLVTVYGGSSSLARQIEAGAPADLFISANEEWVNYLVEKGLVKPNKVVTLAANSLVLIRPTAQPVASFELQDAAAWQTALADSRLAVAQVDAVPAGMYAKQALQHAGVWPELESRLAQTNNVRLALALVERGESPLGIVYKTDALLSDKVTIVTAFSAQSHQPIRYPLAQLNDKAASAEWVAYLRSDAAQQILQRFGFESVSE
>NZ_CP053814.1|WP_001960506.1|754111_754807_-|molybdate-ABC-transporter-permease-subunit
MGLSDYEWAALALSLKVAGYATLWLLPIGIVLAWVLARTSFIGKGLIDSLVHLPLVLPPVVIGYLLLISMGRQGFIGQWLYQMFGLSFSFSWRGAVLACMVIALPLMVRSIRLSLESVDQKLEQAARTLGASPMRVFFTITLPLTLPGILTGVMLAFARSLGEFGATISFVSNIPGETQTIPLAMFTFLETPGSEMEAARLCAISIAIALGSLFISEWLSRRMQRRLGLTS
>NZ_CP053814.1|WP_175247252.1|752997_754098_-|molybdenum-ABC-transporter-ATP-binding-protein-ModC
MSEVILQLQKRLGETQLDVDLRLPAVGICAIFGRSGAGKTSLINLISGLTTPDVGEIHLAGRTLFSSSQGIQLPIEQRKIGYVFQDARLFPHYTVRGNLNYGVTDADPEYFASVTRLLALEPLLARYPRDLSGGEKQRVAIGRALLSKPDLLLMDEPLASLDMPRKKEVMPFLENLAQHFRLPILYVSHSMQEILRLADHLVVLEQGKVLSAGPIEQVWSSQAMRPWQSFSEQSTLFSATVAKHHQTYGLTQVRLAEDVWLWVQQVEADVGSSVRMQVRANDVSIALDKPTASSIRNILPARIVAIEHQQPSKKSVSLKLELAPHCYLWAVVTEWANAELALEVGMPVFAQIKGVSVAQRDVILTH
>NZ_CP053814.1|WP_001125116.1|751647_752901_+|hydroxymethylglutaryl-CoA-reductase
MPKLALQPLYSPDVATLAPDRLIDQLAPRFDRPSVRLTPSPALTEQQVMKRWQKLAAPEAQALLLDEQTERTMQAYQKNIEYFIGTVKLPVGIAGPLRVNGSHAQGDYLVPLATTEAALVASYHRGSQLITAAGGASALLLNEGVTRTPVFAFLSLAQAGQFVGWVTSQFEQMKEIAQSTTAHGKLKDIQVNIEGNHVYLVFEYTTGDASGQNMVTIATHAVFEFIMRHSPVAPVQAFLDGNLSGDKKANSYTLRSVRGKKVSAEVHLSAELVKKYLHTTPEQMVQFGQMTTVGGALSGAIGVNAHYANALAALYIACGQDAACVAESAIGMTRMEIHPHGGLYASVTLPNLMVGTVGGGTHLPSQHACLSLMGLAGQGHARALAEVAAALCLAGELSIVGAFCAGHFSRAHHKLAR
>NZ_CP053814.1|WP_001889103.1|751270_751561_+|hypothetical-protein
MSVSAVSNGSSMVMHSSKMMEDAAREIQQASLPVESTIGKPIDPTLQPAPPAPKKQYANHIDALNSLNQASHYSRIGTNLIQRDQDMLGTMLDVRV
>NZ_CP053814.1|WP_001068418.1|751052_751214_+|hypothetical-protein
MNPKQFERWKSQLSQLSPQQLRALQGEIDRSLHQNESALLTEEERDAIAHLFS
>NZ_CP053814.1|WP_001161566.1|750199_750745_-|heme-NO-binding-domain-containing-protein
MQGIIYTVLSDMVIEKFGVLFWDQMLEDLKPSSEGVYTSGQQYNDDELLAMVGYLSEKAQIPAPDLVRAYGEYLFTHLFNSLPENYPHKSDLKTFLLSVDKVIHKEVQRLYPDAYLPQFENRVEEKTLTMSYYSKRQLCAAAEGLILGAAKQFNQPVKITQPVCMHCGADHCEIVVEFLPS
>NZ_CP053814.1|WP_071180508.1|749255_750203_-|histidine-kinase
MSAEAQYQRIYERERKARILAEKLLEEKSRALYDKVLELQSTLEQLNGAQAQLLQSEKMASVGQLAAGVAHEINNPIGFCLSNLNTLRDYAEVFAQLADFVEQSAPSFEGSEFYQAWMRFKQQHDLAFVREDVLSLVEESASGLHRVKDIVTSLQSVSHSSDGRFAECNLNDCIESALRIVWNQFKYTMLVDRQLAENLPNIKGIAPEIQQVLMNMFINASHACDEHGELTITTDTLNEKGKTWVQVQIADNGHGISPEHLAKIFDPFFTTKPVGVGTGLGLSIAFGIVEKHQGKISVTSEVGQGTRFTLLFPAI
>NZ_CP053814.1|WP_001913462.1|747080_749246_+|TIGR01666-family-membrane-protein
MPKINQLRLYWANKTVNYSVLILLTLLGVVIPAWYYQLNTWITPLILGVIAAALADRDDRFSGRLKSIILTLICFAIAAFSIEILFQTPWLFALGLFTSSFGFIMLGAMGARYASIAFASLLVAVYTMLGAHQSTNIWFQPLLLLSGSAWYYLMSMLWHAFWPMQPVQQNLANVFLQLANYLEAKSTLFHPVSNMIPQPHRIIEANLNAATVNALNQCKAVFLTRSKRGHVDSASDRFLNIYFLAQDIHERVSSSHYRYQELADHFGRSDILFRFKYLLETQAKACRDIAQSIRLGHSYQHDSASIVALDELQLSLSYLRQQERRDWKSLLGQLGYLFNNLATVEKQLNNVSNPDVAKPEEGVLDDTEAHTLGSMWQRIRANLSKDSLLFRHALRLSITLTLGYAIIQGFGIERGYWILLTTLFVCQPNYAATKQKLTARIIGTLAGLLIGVPLLTFFPSQESQLVFIVFSGVMFFAFRLNNYGYATGFITLLVLFCFNQLGEGYAVVLPRLADTLIGCALAVAAVVLILPDWQSKRLHKVMAEAIDANKQYLAQIIGQYRIGKKDSLSYRIARRHAHNQDAALSAAVTNMLAEPGRYRAAADESFRFLTLNHALLSYISALGAHRTRLDDETVHQLVLDSHRVIHQHLDLLHQQLSNHCEECDTSGIDSSGLEKRLAEWREDDEGSARMVLQQLHLIYRMLPELHTLASKFAVKVDSQSD
>NZ_CP053814.1|WP_148527892.1|757780_758227_-|hypothetical-protein
MKPSENILVMSDENAFKVLAALGNEYERRGFTNSSNLATFFVNRDFIAKSTNTKELITYYKPKIEQGRYSDLSISQTLLNGMVRSGYLKLDTGKYYLSQTGYNCYLDQNSQVRSFSRLSIVNRFFQEHQTLMFLLTVIGIGIGIASLD
>NZ_CP053814.1|WP_148527891.1|758297_760586_-|DEAD/DEAH-box-helicase
MSIVDIAESIEPINGISELLDILHKEGPVSSEILEKIAYYKKFHSDEFREHEEKIITSLGLFYKLPEPNNLYSFVLSGIGKQHKKEFGEYLTPVQASVRRAVNENKVVSISAPTSAGKSYSIRDFIAEDDGDAVVIVPSRALIAEYVNTMKQKFNGDKNVMISSFVDDIFKSRNLRRIFILTPERARDLFPSNLNLNIKVFFFDEAQVSEEVERGVVFDVLVRRVKQHFDNAKLIFAHPFVENPDAQLKKHNFSEEECYSRSYTHGSVGKIFIYQHNKNKKYYHFSPFIERGHQIKKCVEHEQKFSDFAFDGTHSVLVYVSKASIYNGKFIEPFRKYIDNYEDIDSVEAEEIINTIEHLLGADNDEHNSELVALLRKGIVIHHGSVPLEVRFLVEDLIRKGYAKICFATSTLAQGVNMPFDIVWLDNMRILGDSDQSRSLSFKNLIGRAGRLSNKPKFDFGYVFTKSPQLLSQRVNEKFLLNEQSIIDTPETIDDPDTSELLNSIKEGSFDDDKQAPLSKIERLSESEILKYCEAILSVIYNGDSVKDNLYGAENKGKRESLKQYFRFIYEASINRVLYDGEVAVFRQAISIFLQVIQGRSFREIVGIRYSYISKKDKGRQGYAAFSQPATKLPKSTLTHTYSIFNNDTLAKNVSYDAVVFDTYDYLDQVISFSLTESFITSFKVYKDKTSDQRSDKMIELLRFGTNNTVHTLLIRYGFPPEDISEISRYILFINEDTIMFKPDISDAPKYIKEMVDWYLPG
>NZ_CP053814.1|WP_108335373.1|760582_761317_-|hypothetical-protein
MTDKPKYGSQYSDADWGCDYFKIETDTPIGKIKVCHVVVNDIKIISEALAKKVLDTSWMTNLDVGSKRAYDRTVQETASALVEIFKSTTTPSDVGSEFGEVMVSIGSTKALEKIFNHVILPIAELWKPQLKQNEGFDFHTVCTNNFINFGEAKYSGSTNPHGNAINQSKGFIDDEKHLRDYVHLRELVSHSAVENLNNDSFGIVASFSINTSDPLEVLKNAIKSAQDKLSLDSIKAVYLVGVSK
>NZ_CP053814.1|WP_170826482.1|761660_761918_-|hypothetical-protein
MIAFAKINMAEVNAYAYEGLADMCANSRHITGEQQKELQAIYLQIKHTRQKILPANNDFAHYAAKQLWDIHTTPHYEECIALLKK
>NZ_CP053814.1|WP_175247254.1|762174_762573_+|YgiW/YdeI-family-stress-tolerance-OB-fold-protein
MKRTIIALTSALILAPTLVIAADNAQHIKFIGDSQTQAGVQFQGPVEVVKVQSLLDSSNPFMEKKVVVEGNLVRQLRKDTFMFSDGSNEIQVELDDDIHLNATLTPETKVRLFGEFENGRTPEIEVDHIELL
>NZ_CP053814.1|WP_175247255.1|762813_763335_+|hypothetical-protein
MLKKTHLSLLLGLTLATPPALANNFNYNFLEFRTAMNPESGGVELSTYFTDNSHFIARIDSQLDSDWDIAGGIGFNGPINQFADVYGQMLVHNIRMPKELGGEKDTQLEFNLGARAWLTNQVEGHLRLGRLDDHSVFIAGVRFHSTDQLSLSAEARNAGVWGPQVGMGVRFQF
>NZ_CP053814.1|WP_142566859.1|763705_764680_+|helix-turn-helix-domain-containing-protein
MNSVELKPKSIRLTSHCSSHQSNLLAVHQPVVCQSFGGCLGCHIHTLSGYGRCASSQIHANVDQFCLRLLTVIQGDQLTWYSQECDPMNLHQGKSVLIFSANVFDDVFISETGSYVEIADIRFECQFLASIYQQMGDSLRANGINPLTEKRRFVFDTRVEMQKFISQLQVGLSKQCGTENLYAVSQAYQCLAKLLSKLDSIQCDKKCHDSSSISNRTLNRIRQAHAMMSSEPEKNWSIGELCRQVGTNETSFKRGFKLLFNTTFSKLLQHTRMKIAAEVLRHSDQPIIDIAYQVGYTSPSHFSKLFKQHFGVNPLQYRKNGQAT
>NZ_CP053814.1|WP_001147209.1|764836_765808_+|helix-turn-helix-transcriptional-regulator
MPYYRIPFNLDLLEESIQTNGNIIFKHEQCEFSLRCSLLNDDMVLSQFRGRFEIPTQLDTADKTEYDSVTIMLNLGNAVYYQINGLNCAKILPANSMALCYSDTRHGLCRYQPQVTQLFALQVPRSLLLEYINIMQMGGELKPALEHREPFFLLKPTPSTLQFVALKLAEPQGHSSAIQRQLCYSFISDAVRYLLGGDTAHPQNDGNTHLERAIEILDSEYTLPPTITELARRVGTNETSLKQGFRKELNTTIHQYITQQRMARAAELLNGENYTISHIAHEVGYSNHGHFSAAFKKEFGCTPSTFLSLQSSGQPNALIKKTS
>NZ_CP053814.1|WP_175247256.1|765907_767893_+|TonB-dependent-receptor
MSRNNLTLSPLTLAMALTTFTSSTFARETSYDVMVIESSKQSTLLNRIDSSVLVKTAEELERAGVDQVQDLEKVFPGLLIQTRGNRTYANTTIRGISSPDYYSPTVSVYVDGVLQDSAFLTQPLVNVERVELLRGPQGTLYGGNAQGGIINIITNKAIGQTSALASASYSNLNEQLNGSAALSVNDSLSADIALRAIKDNGNINHLPTQRKDANDSEQFSGLARLHYLPHHSPFTATLSIANSHLDSHEEWYLTQAEFDQKMTSQAIPQLKRIVNSYALQMGYDLGETQLTSVTAYQNRNIYRQFIGGTWQEDQNTLSQELRANTQVSDALSTLIGAYFEQRDFDAKLGVGSQATNQVEATQYALFGQAIYALNEQIDLTLGLRATHLSTRADYSGNPSWMIDAYAQNKSENTLSPKAALGWQITPNSRVFTSISSGYRPGGFSLQPRSSGDKNGYSAEKSLNGELGWRTRLANNMVDLSGALYWIKTDDIQLYTGNPGSQVLRNLGEAQSQGLELQLAFYPTDDLTLNLGGTFGESSFKSGNHDIEGNTLPYAPKTTLVAGIDYVLPQAWFNGAVSLSSNARYTSSVFFNETNTLSQAGYTLVDLAIQYQVNPHLSMRLFSNNVTDQDYKTYSYPIPNSSVALSNYGVGREVGLNIKLEW
>NZ_CP053814.1|WP_000009951.1|767897_769163_+|MFS-transporter
MSFQTAKHSTLSKASLLSLLAGVYTTQSLIGMFTLQGLPAVLRSEGVSTSQIGLFYLAMLPWALKFLWAPYVESIRQQGITLTRHAYLIGLAQTGMLLVLGAFSFNAVISDQTLLFVGVLTLALLSTFADITTDGLAVDVLPADQRRFGNVMQVGGAYLGAVFGGGLFIYLTASVSWQNAILLLMALLLFMSLPTARLFGKSKTSQPLHPTHRPSLKSALTNPKVTLGLGLVALCQLGTRGVQSMMMPFLYDHGVELEALGLLVAGGGIITAFIGIGLSGWLMKKVSAISMVLVCLALEALLYAGFTFYSYSAQITPLTYGLEGLYVLNTVLVAAKFVALYTLMMDWSYGDQAGVDFSLFQSMDMLIAMLMAMLCGWIIAQFGYQVHYLLTFSVTLCALLTLYQFHAYQLRLGNKDICHVS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053813

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP053814

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection