CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053820	Vibrio cholerae strain SA10G chromosome 1, complete sequence	3 crisprs	cas3,DEDDh,DinG,csx1,csa3,cas6f,cas7f,cas5f,PrimPol	0	5	5	0
NZ_CP053821	Vibrio cholerae strain SA10G chromosome 2, complete sequence	0 crisprs	csa3,cas3	0	0	0	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053820_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053820_1

1954857-1955003

TypeI-A

Consensus_repeat	Method
TTTCTTGGCTGCCTATTCGGCAGAACAC	PILER-CR
TTCTTGGCTGCCTATTCGGCAGAACAC	CRISPRCasFinder

2 spacers

csa3,cas6f,cas7f,cas5f

The CRISPR arrays of NZ_CP053820_1

>merge|NZ_CP053820|1|1954857-1955003|PILER-CR,CRISPRCasFinder
TTCTTGGCTGCCTATTCGGCAGAACACCGACCGCAAGAGTTCTGCTCGCGCTTGGTGAATTTCTTGGCTGCCTATTCGGCAGAACACGCGTAATGAAGCCACTGGTGAAATGGGCTGGCTTTCTTGGCTGCCTATTCGGCAGAACAC

>NZ_CP053820|1|1|1954857-1955003|PILER-CR
TTCTTGGCTGCCTATTCGGCAGAACACC	GACCGCAAGAGTTCTGCTCGCGCTTGGTGAAT
TTCTTGGCTGCCTATTCGGCAGAACACG	CGTAATGAAGCCACTGGTGAAATGGGCTGGCT
TTCTTGGCTGCCTATTCGGCAGAACAC

>NZ_CP053820|1|1|1954857-1955003|CRISPRCasFinder
TTCTTGGCTGCCTATTCGGCAGAACAC	CGACCGCAAGAGTTCTGCTCGCGCTTGGTGAAT
TTCTTGGCTGCCTATTCGGCAGAACAC	GCGTAATGAAGCCACTGGTGAAATGGGCTGGCT
TTCTTGGCTGCCTATTCGGCAGAACAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053820.1\|WP_114717055.1\|1964553_1965729_-\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341196
NZ_CP053820.1\|WP_142731499.1\|1950166_1953136_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379062
NZ_CP053820.1\|WP_175246131.1\|1956787_1958875_-\|hypothetical-protein	cas5f	cd09736_cas5f_CAS-I-F	gnl\|CDD\|187867
NZ_CP053820.1\|WP_057554272.1\|1947721_1948723_-\|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|169599
NZ_CP053820.1\|WP_162902602.1\|1949993_1950170_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_069212616.1\|1960199_1960883_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_123011425.1\|1947210_1947708_-\|dual-specificity-protein-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|350355
NZ_CP053820.1\|WP_119298336.1\|1954211_1954610_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_114717057.1\|1958877_1960089_-\|TniQ-family-protein	unknown	unknown	gnl\|CDD\|377670
NZ_CP053820.1\|WP_175246128.1\|1942112_1945328_-\|chitinase-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|225862
NZ_CP053820.1\|WP_175246129.1\|1953391_1953799_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	unknown	unknown	gnl\|CDD\|182350
NZ_CP053820.1\|WP_175242641.1\|1945942_1947166_-\|organoarsenical-effux-MFS-transporter-ArsJ	unknown	unknown	gnl\|CDD\|340883
NZ_CP053820.1\|WP_114717056.1\|1960901_1964519_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NZ_CP053820.1\|WP_038939483.1\|1967538_1968405_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198394
NZ_CP053820.1\|WP_000936745.1\|1948819_1949161_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|236654
NZ_CP053820.1\|WP_114717054.1\|1965728_1967336_-\|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|223363
NZ_CP053820.1\|WP_057557756.1\|1941192_1942023_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NZ_CP053820.1\|WP_123011419.1\|1955749_1956781_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09737_cas7f_CAS-I-F	gnl\|CDD\|187868
NZ_CP053820.1\|WP_175246130.1\|1955099_1955738_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09739_cas6f_CAS-I-F:CAS-IV	gnl\|CDD\|187870
NZ_CP053820.1\|WP_114717053.1\|1968401_1969784_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989

Protein	Function_ID	Function_description	E-value
NZ_CP053820.1\|WP_114717055.1\|1964553_1965729_-\|restriction-endonuclease-subunit-S	gnl\|CDD\|341196	cd17515, RMtype1_S_MjaORF132P_Sau1132ORF3780P-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to MjaXIP/S.MjaORF132P TRD1-CR1, S.Sau1132ORF3780P TRD1-CR1, S.Mca353ORF290P TRD1-CR1, and other TRD-CR's. The Staphylococcus aureus subsp. aureus MSHR1132 S subunit (S.Sau1132ORF3780P) recognizes 5'... CAAGNNNNNRTC ... 3', and Moraxella catarrhalis S subunit (S.Mca353ORF290P) recognizes 5'... CAAGNNNNNNTGT ... 3'. The recognition sequence of Methanococcus jannaschii S subunit (MjaXIP/S.MjaORF132P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.Sau1132ORF3780P-TRD1 recognizes CAAG/CTTG, and S.Sau1132ORF3780P-TRD2 recognizes GAY/RTC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	9.75567e-89
NZ_CP053820.1\|WP_142731499.1\|1950166_1953136_-\|AAA-family-ATPase	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	7.72396e-09
NZ_CP053820.1\|WP_114717053.1\|1968401_1969784_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	3.3374e-30
NZ_CP053820.1\|WP_057554272.1\|1947721_1948723_-\|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|169599	PRK08955, PRK08955, glyceraldehyde-3-phosphate dehydrogenase; Validated.	0
NZ_CP053820.1\|WP_175242641.1\|1945942_1947166_-\|organoarsenical-effux-MFS-transporter-ArsJ	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.10728e-15
NZ_CP053820.1\|WP_123011425.1\|1947210_1947708_-\|dual-specificity-protein-phosphatase-family-protein	gnl\|CDD\|350355	cd14505, CDKN3-like, cyclin-dependent kinase inhibitor 3 and similar proteins. This family is composed of eukaryotic cyclin-dependent kinase inhibitor 3 (CDKN3) and related archaeal and bacterial proteins. CDKN3 is also known as kinase-associated phosphatase (KAP), CDK2-associated dual-specificity phosphatase, cyclin-dependent kinase interactor 1 (CDI1), or cyclin-dependent kinase-interacting protein 2 (CIP2). It has been characterized as dual-specificity phosphatase, which function as a protein-serine/threonine phosphatase (EC 3.1.3.16) and protein-tyrosine-phosphatase (EC 3.1.3.48). It dephosphorylates CDK2 at a threonine residue in a cyclin-dependent manner, resulting in the inhibition of G1/S cell cycle progression. It also interacts with CDK1 and controls progression through mitosis by dephosphorylating CDC2. CDKN3 may also function as a tumor suppressor; its loss of function was found in a variety of cancers including glioblastoma and hepatocellular carcinoma. However, it has also been found over-expressed in many cancers such as breast, cervical, lung and prostate cancers, and may also have an oncogenic function.	1.22502e-59
NZ_CP053820.1\|WP_114717057.1\|1958877_1960089_-\|TniQ-family-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	4.31425e-11
NZ_CP053820.1\|WP_175246128.1\|1942112_1945328_-\|chitinase-C-terminal-domain-containing-protein	gnl\|CDD\|225862	COG3325, ChiA, Chitinase [Carbohydrate transport and metabolism].	7.8816e-171
NZ_CP053820.1\|WP_175246129.1\|1953391_1953799_-\|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit	gnl\|CDD\|182350	PRK10276, PRK10276, translesion error-prone DNA polymerase V autoproteolytic subunit.	1.19046e-28
NZ_CP053820.1\|WP_057557756.1\|1941192_1942023_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	3.55448e-12
NZ_CP053820.1\|WP_114717056.1\|1960901_1964519_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NZ_CP053820.1\|WP_038939483.1\|1967538_1968405_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198394	cd10447, GIY-YIG_unchar_2, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria and archaea. The family includes a group of uncharacterized hypothetical proteins, mainly found in bacteria and a few found in archaea, with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	1.18258e-37
NZ_CP053820.1\|WP_000936745.1\|1948819_1949161_-\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|236654	PRK10141, PRK10141, DNA-binding transcriptional repressor ArsR; Provisional.	2.94409e-27
NZ_CP053820.1\|WP_114717054.1\|1965728_1967336_-\|SAM-dependent-DNA-methyltransferase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	1.39742e-56
NZ_CP053820.1\|WP_175246131.1\|1956787_1958875_-\|hypothetical-protein	gnl\|CDD\|187867	cd09736, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	4.87264e-20
NZ_CP053820.1\|WP_123011419.1\|1955749_1956781_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|187868	cd09737, Csy3_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas7 ortholog.	5.48457e-151
NZ_CP053820.1\|WP_175246130.1\|1955099_1955738_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	2.23201e-48

>NZ_CP053820.1|WP_119298336.1|1954211_1954610_-|hypothetical-protein
MSKKKLTEKVLLEGMTPYNTHSDLLAKTETKTDWMSFADEVELVTHDFMTNRNEVFDEPSSDLVNPDIFLSNLKLALDNLPDGDIELCDLGNEIGRIIANLNSPNKTLLREVIYGVEHGFDLVSKERGSSNG
>NZ_CP053820.1|WP_175246129.1|1953391_1953799_-|translesion-error-prone-DNA-polymerase-V-autoproteolytic-subunit
MKVIPIFAHAGITGFESPAEEYTQLALDLDQLLIEHPCATFLGYACGDSMQDVGIFDKDLLIVDRSLDVQDFDIIVANLNGEFICKQIDLNRRLLLSANERYQPVPIHEFEQFSLEGIVTRSICCHRVSPLWRTR
>NZ_CP053820.1|WP_142731499.1|1950166_1953136_-|AAA-family-ATPase
MFEFTGREQELNILKSAWDKALQGKAQWVSIYAESGIGKTRLVHEFYHYFIQSTNQVSSGNTVKGYWPDQLPSDTHDLKLNPDISLFNNDTISSLNELPSLWWGMRCSEKGRRNSSNSSSAIYDFLPQLLPHLAILKSISARQDNYKSVAIDLGKKAISIATGGVVDVGIMLYELCENLDTLSKNTYSTNSRAAYEQQRVELSESVLKAFRTITEKQVPLVLVIDDIQFIDSETLAFIEAIKGITSQKLLIITTCWAREWASHPLAESISGFPGEFREIELATVNSDSVDAILQNTLPGLSKQHRTTIATRSDGNLQYLYEICYLLKENPDEFFIDESSSNDFFPGAEEILLSERFNIERLIKERFSKLHPDVKSMLVAGSFQGPKFSSALLENFSTTNILDAELIGCSSLLKQAVKPGYFLTYEHEFLYKFSQRGYWEIANKRLENPNTRSSIIEYYTEKTREIDTLNIDVSSKFNLIYAVLPYMPIEEQLKLSLKACNLLVNMGRYREALAYYSQADSIFRERASYSDSEYLGSLSGEMIQSIYQIASYFPLYIHSNQNVEEKLRTKKGLKSFIPFRLTSFDLPETYPENELELKCYLDQTYLDFQSSRQLGYTLDEHQRLKSYLTVQKHVFDSRREMITSDMLFRYLLCICRHIHLSSLFTNNLEQWQEFHHWLNKEHHYLIEIIDGGVFNDSPHSIQHLRSLAHCSLQTSILAWTQKSWQFYGKEIPVSQNYNAYCAVADFIADSYHLGILCENDVNQTQSISTDNLALLVNIEDEIHLVSAMYGYPLSVDFSLRVLERIGKLFEDELTTSPEVLVGSTNAMIGIINNIEFGKKKREESVNQENIKYVSPALKVILISEEELQTKCILDISKKQHAYLSRIIEEHRHTVDVLITICRLEHQTLYMQSNSLTEESKLTWFEKAFHYAYLANDADLLVHGEVAPFINFFASELSKLPRDSKVYERIDQLGIELYGRSWGKFKELFNA
>NZ_CP053820.1|WP_162902602.1|1949993_1950170_-|hypothetical-protein
MIMTQQEFELFLEAKYPQLFGTDIALGASCAYFGDCDRSFQDSHIPIGHRVLRHRFTL
>NZ_CP053820.1|WP_000936745.1|1948819_1949161_-|metalloregulator-ArsR/SmtB-family-transcription-factor
MLPHQFFKLLADETRVRCLLMIAREEKVCVAELTEALNESQPKISRHLALLRASGVVVDIRQGQWVFYRISDQLPGWMRKQIQGLVESNCLKQEYQQDIQRLAEMTSRPQCCV
>NZ_CP053820.1|WP_057554272.1|1947721_1948723_-|ArsJ-associated-glyceraldehyde-3-phosphate-dehydrogenase
MAIKVGINGFGRIGRLALRASFDWPEIEFVQINDVAGDAATLAHLLEFDSVQGRWHHAVSSEADAILINGKRIRTTQEKAIDAVDWSGCDVVIEATGKHRKGEFLNQYLAQGVKRVVVSAPVKEEGIANIVVGVNDHIFNPEQHRIVTAASCTTNCIAPVVKVIHEKLGIAQASFTTIHNLTNTQTVLDAPHKDLRRARACGMSLIPTTTGSAKAIIEIFPDLKGKIDGHAVRVPLANASLTDIIFDVQRDTTVEEINQLLKQASENELKGILGFEERPLVSIDYQGDQRSTIVDALSTMVVGKRMVKIYAWYDNEMGYATRTAELVRKVGLA
>NZ_CP053820.1|WP_123011425.1|1947210_1947708_-|dual-specificity-protein-phosphatase-family-protein
MTHPTWELPVADSQASLVLTPCPGTKGTPLAESIAQLKAQGVSAVVTALSHEEMELHGVGELPAEVEKAGLQWFHAPIEDDCAPDAAFAQDWQQCSPALHQALSRGEKVALHCMGGSGRTGLLAAHLLLEKGWPLESIITQVQALRPGAFTKEVQVQYVHQIVKP
>NZ_CP053820.1|WP_175242641.1|1945942_1947166_-|organoarsenical-effux-MFS-transporter-ArsJ
MLSQLNAHVRQYMLVTFNYWNFTLTDGALRMLVVLYFYDLGYSSLAIASLFLFYEFFGVVTNLIGGWLGARLGLNRTMNIGLGLQIIALLMLAVPASWLTIPWVMAAQALSGIAKDLNKMSAKSAIKTLVPENAQGALFKWIAILTGSKNALKGAGFFLGGALLSLIGFQYAVAAMAAVLVLVFIGSVMSLKSDLGKAKNKPKFSDIFSKSASVNILSAARLFLFGARDVWFVIALPIYLGSVFGWDHSAVGGFLALWVIGYGVIQGFAPKITGSKSEHPPAGRAAIGWALALSSVTGLIAYGVQIQWHPEVVIIGGLMLFGAVFAVNSSLHSYLIVSYAKDDGVSLDVGFYYMANAMGRLIGTILSGWVFQLWGLAACLWVSFGFLVLTTLISFWLPNRASQVNLK
>NZ_CP053820.1|WP_175246128.1|1942112_1945328_-|chitinase-C-terminal-domain-containing-protein
MPTVLALAVGMAMPAAQAAINSDASVVGTESQWWNTYKVTLTNNGSQPVELRGASIVFDTNLSLSTPSWSAQGISYPSMSFSSNAQGSVFSNRLTLSFDQGSWVKTQLLPGASIDLTLGVSGVLDLSLLQSTIALETDGDIEPGQPEISLELASPVQGAEFIEGQTVAIVANVTATNTTVKTVTFLVDGEQIALLEQAPFQANWTAAGEGAHSIKAIVEDASGLLKEQAVRITVKAEEIDPPVEPEVPVAPVIELTNPRNGQSVFLGKVTTLAANATDENNDLTAVEFLVNGESIGRVTQAPYQMAWTPVALGQYTIEAIAYDAAGHQTQTPMVTVNAKEMGTGNLSCDIKQIYREDGTECMGDDHPRRIIGYYTSWRTGKNGLPAYLAGDLPWEKLTHINYAFASINKSDFSMQVDDSATKMTWENVPGAEMDPSLPYQGHFNLLSKFKKQYPDVKTLISVGGWAETGGFYPMTTDLASCSVNMEGIKAFNKSAVDFIRQYDFDGVDIDYEYPSSMKDSGNPVDFEQSNKCRGQLWDNYMVMMTELRKALDKAGEEDGRRYMLTIASPSSGYLLRGMQDFAMQDVLDYVNIMSYDLHGTWNEFVGPQAALFDDGKDAELAKWGVYTTAEYQGIGYLNQAWTHHFFRGAFKPSQINMGIPYYTRGWQGVSGGEKGLWGRAVEPNQSSCPEGTTVCGWGAEGTDNIWHDVDANGNEIKAGVVPMWHAMNLMHAEKLGIDGMPSYGPAWGMDPNNPKHLIEGKYERVWSQELQTAWLWNDTKKVFLSIEDKDSLKPKLDYIVDNGLGGMMIWEMAGDYSYDAVKREYVIGSDMTSYAHEVFAAAEPMDIRHNDLPQPDSVIDVTVSTTEWPEGDSNYPINPKLVFTNHSNVAIPGGSTIEFLMPTSTGDIVKDWSGAGLKVIESGHTGSNFSVNGEKKLFHKVAVTLRSTETIPAGGEYSVDMVYYTPVSGVANGVRFIVGNETVGLKKDFPTLPAFEGATDGGNGNEGGAGQSCADAGINPNGLNVYPEFPRGDHAAGGDQLIHNGSVWQANWWTNSTPSSADASWKAVCKI
>NZ_CP053820.1|WP_057557756.1|1941192_1942023_+|CPBP-family-intramembrane-metalloprotease
MLLSASALLWLPLALAIMAGFARYHRVSWGLLIITLLSALGSGHLTFVGAGIVGIGFALAYLAANGQSLWRTTAWVALLLWCLALFLHWLPGFSNLKVLDKVLASAHSTPFSLYLNLDKPLVFFALLLAFPALLGQSKTANIKATLLTLVPLFTLLPIAVWLGALAFEWSLPEWWWIFALNNLLFTCVAEEALFRGLIQQKAQQQFGAIAGLLIASALFGMAHFAGGPLLMIFAALAGLGYGLVFHFTGRLWVSVGVHFLFNFAHLLFFTYPMLAR
>NZ_CP053820.1|WP_175246130.1|1955099_1955738_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MSQRYYFLIRYTNANADYGLLAGRCISQMHLFMVNHHQAMNRVGVSFPDWNESSVGQTIAFVSEDKEMMIGLSFQPYFSLMVNEGLFEISSVYEVPDTSEEVRFVRNQTIGKNFLGSKKRRIKRSMARAELFGIQQSLPVTNEDRVIDSFHRIPISSGSSRQDYILFIQKELADERAESGFNSYGFATNQEKRATVPDLRFNHFDEDSFLVR
>NZ_CP053820.1|WP_123011419.1|1955749_1956781_-|type-I-F-CRISPR-associated-protein-Csy3
MELCTQLNYVRSLSAGKAYFYYLSESGDMCPLNVDRTRLRAPKGSYSEAYKGNKFVDKNVAPQDLAYSNPQFIEECYVKPGVDEIYCAFSLRIRANSLTPDICSDDEVRSKLSMFAKIYKELNGYKELANRYAKNILLATWLWRNRECRNITIEVTTSELDTFVVEHAQKLSWYGHWDGDSTECLERLTAYLERALSDPTEYFYMDVKAKMRVGWGDEVYPSQEFLDSREDGIPTKQLATVELLSGKETVAFHGQKVGAALQSIDDWWHEEADKPLRVNEYGADREYVIARRHVAYGNDFYQLLRNTENWIESMTASESIPNDVHFIMSVLIKGGLFNCAKAN
>NZ_CP053820.1|WP_175246131.1|1956787_1958875_-|hypothetical-protein
MTKLSDLLAIEDEAIKQAALKKMFMPYTEDVCVDGYEQETLTILLNLSSSHQADRCSDWLDVARAQRYFKDRENLDASLAEIQWFHTHNLKFPDCRVKDQRIIARPLSTAEEFISSAVLDQRLGWAHNSAVYRHTLWLLNPFKWQSQPVCILSLIQQKNLVWLDLLTEFGLDVKSLARLQRAIEEQLPENSFPDSVSTYSKQLRFPWGDDYVSITPVVSHALQCELEIRARSPENKLSFVSSSLPNSASIGNLCGSLGGHMRFLNYPLGVKQTKGGTLTGNRQKSGHYFDDYQVTNAKICQVLNRLIGSEPSKTQRQRERARKVRSKILRKQIALWMLPLIELRDIAESEPNQQQLEHDDTLAQAFLSLPEWELGSLASEFNRRLHLTFQNNMYSAKFAYHPKLMQVAKAQVTWVLEQLSKPINNQDTVTGEQYIYLSSMRVQDAVAMSNPCLCGVPSLTAIWGFMHDYQRQFNQLVNNDSPVEFSSFAFYVRNENIQSTAKLTEPNSVAKARTVSNAKRPTIRSERLSDLEIDLVIRVHSESRISDFRSALKTALPVAFAGGALYQPQLSMQIEWLRTFTGRSELFHVLKGLPAYGRWLYPSEKQPTNFDELERLLTQDDDNLLVSLGYHLLEHPTKRGNAITCCHAYAENAIGLAKRINPIEVRFSGRDHFLNHAFWSIECSSETILIKNYRD
>NZ_CP053820.1|WP_114717057.1|1958877_1960089_-|TniQ-family-protein
MNTDIQLYPDESLESFLLRLSQEQGYERFSHFAEDIWFDTMDQHEAIPGAFPLELNRINIYHAQTTSQMRVRVLIHLENQLKLNNFGALRLALSHSKAQFSPEYKAVHRLGADYPFVFLGQRFTPICPLCISEAPYIRQQWQFLSQQACERHGCKLVHHCPECQSRLEYQTTESISQCECGFELRNSPVEDAPVAALLVARWLSGNDSKPLGLLKAEMTLSERYGFLLWYVNRYGDIENISFESFVEYCSCWPRVLKEELDELVNKADLIRIKDWKKTFFNEVFGALLKDCRQLPSRQLERNSVLTQVLAYFTKLMATLPLSSKGNVGDVLLSPLEVSTLLSCTTDEVYRLYEFAEIKAAIRPRMHTKIASHESAFTLRSVIETKLTRMCSENDGLSVYLPEW
>NZ_CP053820.1|WP_069212616.1|1960199_1960883_-|hypothetical-protein
MSYLYEYIDELLRLQSRAVEKFKHTGVLGDAREEFLRYQINERLDHVDGRLHKGEVFYQNIEHGQHDIILRRKGTVNPCIGNQVRICSTECVAIIEVKTNAKLTEIRDFERKSKQLKIHNENLLCGMFCYKINGQTSTVLARSGYIFDREYQMFEPDDSKKEYSSIDFIICLDDEEEVNGLSHSKEPIVYSKGFCLVRDSSSYKLFKAPPYSKTLFQEMMRADQSKP
>NZ_CP053820.1|WP_114717056.1|1960901_1964519_-|DEAD/DEAH-box-helicase-family-protein
MSDTVDSKGAQGDSNFAFMDVACGGGSDVYTTRCAEIQTRAKNAERNIKTDPRIAGFYARNALELMVETVFDIDNWLTRPRHDVALMSLIHDSGFKQSLTTNLFPKLKLVIKVGNEAVHSKTTLPQRDALQAVKELHHVLYWFIRTYTPNLDRSQFVVPPFDEALIPQQVSIDAAVATKALSSIKRVQELEKLLEQADKVERDAYLKQLKENEALKAANQALLEQIEQAKQSAEKVTDAHDYNEAETRTYLIDVLLHEAGWKLEHKRDREYPVSGMPISQANPNGNGFVDYVLWGDDGTALAVVEAKRTHRRAEDGQQQAKLYADCLEKQCGVRPVIFYTNGYETYLWDDHFYPPRQVQGFYTKAELELMVKRRTDRKPFFENGQPNSNLVINNDITNRHYQKSAITKLLQDFELEHERKGLFVMATGTGKTRTVISLVDLLVKNNWVKNILFLADRNALLTQAKKNFVKLLPRVSCSILDSSQSKDNIDSRLYFSTYPTMKNLLDRGANERPFGVGHFDLIVVDEAHRSVYSKYRQIFEYFDGFLLGLTATPKDEVEKDTYGIFDLQKGMPTYAYEDEKAYDQGFLVPPTKISVATKFLREGVKYKDLSPEEQEEWENKAELQDRDEVLPSEVNKFLFNQDTAEKMFAQLMSKDEHGGIHVEGGDVIGKTIIFAANNDHALFLEKMFNKNYPKWAGKLARVITFKETYAQSLIDEFSGDENERKDFDPKNPTCRIAISVDMLDTGIDVPEVVNLVFFKVVRSKVKFTQMIGRGTRLCKDLFGPNDDKKTFKVFDYCQNFEYFDANPEGLPVGVAKPVTQQVFEKRVLLSTLLNSKLNNEDFREQNPEDYERYSELNRYQLDMLHHIVSGMNLDNFIVRPKRRAIEPFLDRKYWDNIDDAKFSELENQISQLPTEAEAFNSDEQLNHLSHRFDSLVLTMQLDLLEKGMISEMLRGRVIEFAEQLEAKSTIPAVQAQLQLIQDVQTQEFWQDIHLVTLEELRRKLRNLMFALDKDKKEMVYTNFADEVQGVHDVTNVYKNPSVDLAQYRKKIELYIQDHQDHLTIQKLKRNKAITQADLDVLEGLLLEASGISDVETYREKILQEKPLGTFIRQLVGLDQNAAREAFSAFLDEASYNAEQIEFIDQVIDYLVNNGILDMSQLFEPPFTDNHGESAYGFFDEGTVVELFGVIRKVNANAVVAESQSA
>NZ_CP053820.1|WP_114717055.1|1964553_1965729_-|restriction-endonuclease-subunit-S
MEFVTLGDLFKISSGGTPSRREKSYYDNGDIPWIKTGDLHKCRIQQASEYITQLGLDKSSAKLFPKGTVLLAMYGATIGACSILDIEAATNQACAAFLPNEKVDTNYLYYFLISKKNDFIRDGVGGAQPNISATYLKTVSFPLPPLETQKQIAAVLEKADQLRKDCKLLEQELNSLAQSVFIDMFVGKDFPLVNLEDLASNKKHALSSGPFGSALSSKHYTDEGVLVLRGLNTTKGKIDLSKTKYISQEKYEELKRSKLSVNDVVVVAVGSSGFAISIPDGFPEAVMSQNFNKISPNMDLIVPKYLEFAINSSFVQRQFSREITDTVRTFLSLTKLKKVQIPLPPLELQKQFLSTIKSILKEEELNQEFVSEMDNCFSSLMQKAFKGELTL
>NZ_CP053820.1|WP_114717054.1|1965728_1967336_-|SAM-dependent-DNA-methyltransferase
MLTGKIRNQIDQVWEMFWTGGVANPISVIEQISYLLFIRRLDELQKTAERRSQATGLPLNNPTFGPDEQALRWSNFKDKDPDVMMEIVRDRVFPKIKTLQNEGSFAEHMKDAIFMIPSAKLLDQVVQLLSAINMDDKDTKGDLYEYLLSKLQQSGVNGQFRTPRNIIRMMVELMQPKVGDTICDPSSGTCGFLMAAVEYVEEHHAKEVNKPENRKHFNNEMFTGFDFDRHMLRIGAMNMLLHGIENPSVHYRDSLQDQGSENISEAYSLILANPPFKGSVDFDIVAPDLLRALGKNPIVKKSAPKFKTEIDEDGNEIQVEVKQKGPTEKSELLFLALILRMLKVGGRAAVIVPDGVLFGSTKSHQSIRQKIVNEQKLEAVISLPSGVFKPYAGVSTAILIFTKTNSGGTDNVWFYDMQADGYSLDDKRTQLFKEGEVPTHEQSNIADIIARFKTLTNADNTPNSDSPEYQRKRTEQSFMVPVSNITNNDFDLSINRYKEVVYEEVQYDSPKEILGRIKTLQEKMAKGVAELEKLL
>NZ_CP053820.1|WP_038939483.1|1967538_1968405_+|GIY-YIG-nuclease-family-protein
MTRGTQLKIYLANGSVTGIRHAEIVNWTGQAIAVPRVHIKELSEWEETHRPGVYFLFGYNADSGNSLVYVGEAEHIQKRLSQHLAGKEFWNEAICFTNKDENLTKAHVKYLEARLIEIIVESKRYDLDNDKLPPASSLPRGERDAMETFIDNIRTVIGSLGHKLLEPRVSLTSPSQTNEPENTVLQLKVKKVDAKAMLTDEGIVVLKGSQALTTAQPSLSKGYTKLRSNLEEKGILTPSGDHLVAVEDILFTSASQAAAVLLGYPCSGPDYWRDTSGKTLKEIEAESV
>NZ_CP053820.1|WP_114717053.1|1968401_1969784_-|DEAD/DEAH-box-helicase-family-protein
MLRVWQADCAEQAINKFASNRRPHFFCQATPGAGKTVMAAEVAMRLFEKDMIDLVLCFSPSLSVAEGMQKTFAWKLECSFNGGLGSLGGSYTYQSIRFFDDNFWNTISKHRVLVVFDEIHHCSFEEDGRSNSWGVEIVSKIQGLARYTLALSGTPWRSDRLPIVMAEYSDPEGMLICDYQYGLKQAVVDGVCRQPKIALIDNEHLSITSGGNRQHFASILDCLKQSDISYQSVIHNEEAMHYILNSACKKLAQIRELSPNAGGLVVAASIKHAKDIQKRLVEQFNQSASIVTYHHVNPLNEIESFRHSNVQWIVSVGMISEGTDIPRLQVCCHMSSVKTELYFRQVLGRILRVNDSVNQEAWLYTFAEESLIGFAERIEQDIPDTCMFLKQEEEAQNVADEPISLSSTVSDRIQSSYSQPSTLSWENIAAVIESNNTNNALLYDELRLGQFKQRVIAAFT

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP053820_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053820_2

2576678-2576921

Orphan

Consensus_repeat	Method
AAAATGTGCCTCCTTAGCTCAGTCGGTAGAGCAACGGACTGATAATCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP053820_2

>merge|NZ_CP053820|2|2576678-2576921|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAATTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAATTGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

>NZ_CP053820|2|2|2576678-2576921|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGG	TCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAA
TTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTG	TCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAAT
TGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053820.1\|WP_175246230.1\|2580898_2583250_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP053820.1\|WP_175246228.1\|2571880_2572801_-\|glutaminase-B	unknown	unknown	gnl\|CDD\|234880
NZ_CP053820.1\|WP_000741914.1\|2569239_2569530_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP053820.1\|WP_033930630.1\|2570076_2570679_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP053820.1\|WP_175246231.1\|2586871_2587681_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|234673
NZ_CP053820.1\|WP_001087261.1\|2568682_2569240_+\|YggT-family-protein	unknown	unknown	gnl\|CDD\|223833
NZ_CP053820.1\|WP_175246229.1\|2573870_2574932_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|182805
NZ_CP053820.1\|WP_071180449.1\|2577213_2578839_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP053820.1\|WP_000546924.1\|2579885_2580740_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP053820.1\|WP_000383338.1\|2586480_2586861_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP053820.1\|WP_000780522.1\|2583302_2584598_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758
NZ_CP053820.1\|WP_000124738.1\|2574945_2575218_+\|oxidative-damage-protection-protein	unknown	unknown	gnl\|CDD\|180059
NZ_CP053820.1\|WP_114812678.1\|2575319_2576447_+\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
NZ_CP053820.1\|WP_000005583.1\|2572911_2573631_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP053820.1\|WP_000095775.1\|2584587_2585580_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP053820.1\|WP_069647711.1\|2587830_2588328_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_CP053820.1\|WP_069731232.1\|2569575_2570007_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616
NZ_CP053820.1\|WP_000954087.1\|2588340_2588814_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|182143
NZ_CP053820.1\|WP_001243262.1\|2585593_2586409_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP053820.1\|WP_175246227.1\|2570672_2571848_+\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550

Protein	Function_ID	Function_description	E-value
NZ_CP053820.1\|WP_175246230.1\|2580898_2583250_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP053820.1\|WP_175246228.1\|2571880_2572801_-\|glutaminase-B	gnl\|CDD\|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
NZ_CP053820.1\|WP_000741914.1\|2569239_2569530_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	1.27614e-60
NZ_CP053820.1\|WP_033930630.1\|2570076_2570679_+\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	1.50746e-127
NZ_CP053820.1\|WP_175246231.1\|2586871_2587681_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|234673	PRK00166, apaH, symmetrical bis(5'-nucleosyl)-tetraphosphatase.	3.79883e-168
NZ_CP053820.1\|WP_001087261.1\|2568682_2569240_+\|YggT-family-protein	gnl\|CDD\|223833	COG0762, COG0762, Predicted integral membrane protein [Function unknown].	2.77868e-12
NZ_CP053820.1\|WP_175246229.1\|2573870_2574932_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP053820.1\|WP_071180449.1\|2577213_2578839_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.37816e-58
NZ_CP053820.1\|WP_000546924.1\|2579885_2580740_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.60415e-153
NZ_CP053820.1\|WP_000383338.1\|2586480_2586861_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	1.16069e-74
NZ_CP053820.1\|WP_000780522.1\|2583302_2584598_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	1.14348e-156
NZ_CP053820.1\|WP_000124738.1\|2574945_2575218_+\|oxidative-damage-protection-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	5.47988e-59
NZ_CP053820.1\|WP_114812678.1\|2575319_2576447_+\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	6.18929e-156
NZ_CP053820.1\|WP_000005583.1\|2572911_2573631_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	6.44859e-111
NZ_CP053820.1\|WP_000095775.1\|2584587_2585580_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP053820.1\|WP_069647711.1\|2587830_2588328_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	3.9817e-90
NZ_CP053820.1\|WP_069731232.1\|2569575_2570007_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	1.39708e-66
NZ_CP053820.1\|WP_000954087.1\|2588340_2588814_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|182143	PRK09917, PRK09917, threonine/serine exporter.	7.45224e-67
NZ_CP053820.1\|WP_001243262.1\|2585593_2586409_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.27746e-146
NZ_CP053820.1\|WP_175246227.1\|2570672_2571848_+\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0

>NZ_CP053820.1|WP_114812678.1|2575319_2576447_+|membrane-bound-lytic-murein-transglycosylase-MltC
MRKLVLCITTLLLSGCSREFIEKIYDVDYEPTNRFAKNLAELPGQFQKDTAALDALINSFSGNIEKRWGRRELKIAGKNNYVKYIDNYLSRSEVNFTEGRILVETVSPIDPKAHLRNAIITTLLTPDDPAHVDLFSSKDIELKGQPFLYQQVLDQDGQPIQWSWRANRYADYLIANHLKVKQVDFKKAYYVEIPMVKDQIDIRGYKYASIVRKASRKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKNRSGEPSPEYLFNPENNIDTGTAYFYILKNRYLKEVRHPTSLEYSMISAYNGGTGGVLSTFSSDRQRAMRDLNALQPNQVYWALTKKHPNAEARRYLEKVTKFKKEFNAG
>NZ_CP053820.1|WP_000124738.1|2574945_2575218_+|oxidative-damage-protection-protein
MARTVFCTRLQKEADGLDFQLYPGELGKRIFDNICKEAWAQWQTKQTMLINEKKLNMMDPEHRKLLEQEMVNFLFEGKEVHIEGYTPPAK
>NZ_CP053820.1|WP_175246229.1|2573870_2574932_+|A/G-specific-adenine-glycosylase
MTPFAQAILTWYDAYGRKNLPWQQNKNAYRVWLSEIMLQQTQVATVIPYFERFLERFPTVQALAAAPQDEVLHFWTGLGYYARARNLHKTAQMVVSEYGGEFPTDLEQMNALPGVGRSTAAAVLSSVYKKPHAILDGNVKRTLARCFAVEGWPGQKNVENQLWHYAEMHTPKVDVDKYNQAMMDMGAMICTRSKPKCSLCPVESFCLAKQQGNPQEYPGKKPKTDKPVKATWFVMLYHDNAVWLEQRPQSGIWGGLYCFPQSEIANIQTTIDQRAIGDSTITSQKTLIAFRHTFSHYHLDITPILLQLSRKPDIVMEGSKGLWYNLSQPDEIGLAAPVKQLLHSLPFDIDSHI
>NZ_CP053820.1|WP_000005583.1|2572911_2573631_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVITQEYTEDGKVLRRIRSFVRREGRLTKGQEAAMKECWPTMGIDYQPELLDWQQVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHDAVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLIIGSGVFHMATDWENYAEHMVEVMNQAPGFANLATDGDYIPRPDERPLTKFEQRGHRLGHGVWDIKYQRTA
>NZ_CP053820.1|WP_175246228.1|2571880_2572801_-|glutaminase-B
MKPTAEILASIIEEVRPLTSKGIVADYIPALAKVPSEKLGIAVFTNQGEVITAGDAQEGFSIQSISKVLSLTLAMGLYQPDELWSRVGKEPSGQAFNSLIQLEMEHGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPQIAYDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSKQTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF
>NZ_CP053820.1|WP_175246227.1|2570672_2571848_+|radical-SAM-family-heme-chaperone-HemW
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGDIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEGIARLLQGVAERIVFKPDIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAQLAHKIGLNSFNLDLMHGLPDQTPEQALADLDQAIVLNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQYEISGYSKLGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWALSEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE
>NZ_CP053820.1|WP_033930630.1|2570076_2570679_+|XTP/dITP-diphosphatase
MKKIVLATGNQGKVREMADLLSDFGFDVIAQSEFNVPEAAETGTTFIENAIIKARHAAQITGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLAAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTAPHGSNGFGYDPIFWVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRKC
>NZ_CP053820.1|WP_069731232.1|2569575_2570007_+|DUF4426-domain-containing-protein
MRKWIMSLLLTLLALPASAEQQKTIKDIEVHYSAFNSTFLTPKVASSYQLTRNGYTAILNISVLDRASLGKPATEAKLTGHAKNLIGNLRELSFKQVKEGNAIYYLAEVPISNEEMLTFDIDVDAGLKGAGKLTFSQKFYTEQ
>NZ_CP053820.1|WP_000741914.1|2569239_2569530_+|YggU-family-protein
MAAVWREGDDLLLRLYIQPKASRDSIVGLHGEELKVAITAPPIDGKANAHLSKYLAKLCKVAKGSVVIEKGELGRHKQVRILQPSQIPAEIAALIE
>NZ_CP053820.1|WP_001087261.1|2568682_2569240_+|YggT-family-protein
MNSLSFLINTLFDLYIMVVILRIWLQAARADFYNPFSQFIVKATQPVVGPLRRVIPSIGSIDLATIVFAYVLCVLKFMALVLIASSGSVSFSADFLFLGLLSLIKAAGGLLFWVLLIRAILSWVSQGRSPIEYVFHQLTEPMLAPIRRIIPVMGGFDLSILVLFIVLQFANFLMGDVIGPIWYQL
>NZ_CP053820.1|WP_071180449.1|2577213_2578839_+|methyl-accepting-chemotaxis-protein
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSIGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAFAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFAIKAPKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVADLDLDVKNIAKVLDVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQIATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR
>NZ_CP053820.1|WP_000546924.1|2579885_2580740_-|co-chaperone-DjlA
MHIFGKILGAFFGFLFGGPFGAIFGIFLGHQFDKARRLNQAGFQSGTFGAGPSQAERQEEFFKSAFSVMGHVAKAKGQVTKEEIQLATIMMDRMNLTLEQKRAAQDAFRDGKESDFPLEQVLERVKIATGGRFDLLQFFLELQVSSAFADGDVHPSERQVLHRIARGLGFSSEQLERRLRMQEAAFRFQQGGGFGGSQQQSHSGQQWQQPSSRHQLADAYEVLGVSESASAQEVKRAYRKLMNEHHPDKLMAKGLPPEMMNVAKEKSQQIQHAYELIRKEKGIK
>NZ_CP053820.1|WP_175246230.1|2580898_2583250_+|LPS-assembly-protein-LptD
MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLTDDQLHTELGDRWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSDLDSGVGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTKDTTSTNLPYRLMPQLSYNYYAPETMKYLDLDLVSHISRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVTRVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTLLQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNKNPDSTSDKTSYSAWAVEMDFNFADYLFYHGGIQYDIDSQAVQLGNSTLEYRVASGYIQANYRYVAKDYIRNTVGDSITNIDDITRDGISQAGILAGYQLSRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFTYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
>NZ_CP053820.1|WP_000780522.1|2583302_2584598_+|peptidylprolyl-isomerase-SurA
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISHIQLRVDDGQDKSAAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPTIFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILFNRKFNEEASAWLQELRASAFVEVLKDEKDEQ
>NZ_CP053820.1|WP_000095775.1|2584587_2585580_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSSKRIIVTAGEPAGIGPDLVLALSAQDWPHQLVVCADKALLAQRATQLGIQVKLLDYQRDNPVQAQQAGTLLVEHISLAEPVVAGQLNPANGHYVLKTLERAAKGCMNGEFDAIVTGPVHKGVINRAGVAFSGHTEFFAEQSKTPLVVMMLATEGLRTALVTTHLPLAEVPQAITCERLEQIVHILHKDLVEKFAIAEPKIYVCGLNPHAGEDGVLGMEEIETITPTLQRLREQYGMQLVGPLPADTIFSEKYLQQADAVLGMYHDQVLPVLKYKGFGRSVNITLGLPFIRTSVDHGTALDLAGTGQADAGSFWTALAYAIELVDKKAQ
>NZ_CP053820.1|WP_001243262.1|2585593_2586409_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MRNDVHLGHKARKRFGQNFLNDPYIIDGIVSAINPKPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELASKLTIHEGDAMRFDFKQLVKPNNKLRVFGNLPYNISTPLMFHLFEFHRDIQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYYCKVVPVLEVPPSAFVPPPKVDSAVVRLVPYEDLPHPATSLEWLDRVVREGFNQRRKTVRNCYKGLAEPETLETLGINPGMRPENLTLAQFVALANWLDATHKTHA
>NZ_CP053820.1|WP_000383338.1|2586480_2586861_+|Co2+/Mg2+-efflux-protein-ApaG
MDVSLPCIKIQVQTRYIEEQSNPEYQRFVFAYLITIKNLSSQTVQLMSRRWLITDADGKQTVVEGDGVVGEQPRIKANDEYTYSSGTALDTPVGVMQGQYLMIDEQGESFTVEIEPFRLAVPHVLN
>NZ_CP053820.1|WP_175246231.1|2586871_2587681_+|symmetrical-bis(5'-nucleosyl)-tetraphosphatase
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFAYQLGDAARVVLGNHDLHLLSVALGHHSAKRRDQTQVILDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPQEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIGLDTGCVWGGTLTMLRWEDKHYFSQAALPA
>NZ_CP053820.1|WP_069647711.1|2587830_2588328_-|type-3-dihydrofolate-reductase
MMISMIAAMADQRIIGKDNQMPWHLPADFAWFKRCTLGKPVVMGRKTYQSIGRPLPGRHNIVISRDASLQIEGGDVVTSIEAALVKAGEVDEVMIIGGGSLYAACLPMAHKLYITEIHAKLEGDTQFPEWGSDWLERSREHYPADEKNAYGMDFVIFERQYPLPT
>NZ_CP053820.1|WP_000954087.1|2588340_2588814_-|threonine/serine-exporter-family-protein
MLSWDLFFGLLNDMFFAAIPAVGFALVFNVPVPALKYCALGGALGHGSRYLMMHFGVPIEWASFFAATLVGMVGVYWSRRFLAHPKVFTVAALIPMVPGVFAFKAMIALVEINHVGFSPELMEALLENFLKAMFIIAGLAVGLAVPGLLFYRRKPII

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP053820_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053820_3

3001959-3002043

Orphan

Consensus_repeat	Method
CCCCCCCTTGCCACGCATAATTACCCCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP053820_3

>merge|NZ_CP053820|3|3001959-3002043|CRISPRCasFinder
CCCCCCCTTGCCACGCATAATTACCCCCCTGACTACTGACGATCTGCGCATAATCACCCCCCCTTGCCACGCATAATTCCCCCCC

>NZ_CP053820|3|2|3001959-3002043|CRISPRCasFinder
CCCCCCCTTGCCACGCATAATTACCCCCC	TGACTACTGACGATCTGCGCATAATCA
CCCCCCCTTGCCACGCATAATTCCCCCCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053820.1\|WP_001747910.1\|2996540_2997152_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_154113085.1\|2997784_3000544_+\|conjugal-transfer-mating-pair-stabilization-protein-TraN	unknown	unknown	gnl\|CDD\|237846
NZ_CP053820.1\|WP_149595617.1\|3004009_3005371_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP053820.1\|WP_000683499.1\|3009547_3010294_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270427
NZ_CP053820.1\|WP_032481337.1\|3002218_3002587_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|200128
NZ_CP053820.1\|WP_011791301.1\|2989255_2989651_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_000901446.1\|2988571_2988841_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_113604264.1\|2990748_2992173_+\|conjugal-transfer-protein-TraH	unknown	unknown	gnl\|CDD\|368759
NZ_CP053820.1\|WP_000505208.1\|3008798_3009470_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP053820.1\|WP_063691921.1\|3000908_3001862_+\|replication-protein	unknown	unknown	gnl\|CDD\|309782
NZ_CP053820.1\|WP_001884349.1\|3007316_3007673_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|179327
NZ_CP053820.1\|WP_001747916.1\|2988308_2988494_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_175246303.1\|2992176_2995581_+\|conjugal-transfer-protein-TraG-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|369594
NZ_CP053820.1\|WP_000593848.1\|3008064_3008802_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP053820.1\|WP_000044781.1\|3007685_3007823_-\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NZ_CP053820.1\|WP_113604263.1\|2989647_2990505_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP053820.1\|WP_000378235.1\|3005464_3007090_-\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|234942
NZ_CP053820.1\|WP_001886301.1\|3007092_3007350_-\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|376620
NZ_CP053820.1\|WP_063691927.1\|2997154_2997688_+\|regulator	unknown	unknown	gnl\|CDD\|377635
NZ_CP053820.1\|WP_032481345.1\|3002583_3003807_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271185

Protein	Function_ID	Function_description	E-value
NZ_CP053820.1\|WP_154113085.1\|2997784_3000544_+\|conjugal-transfer-mating-pair-stabilization-protein-TraN	gnl\|CDD\|237846	PRK14876, PRK14876, conjugal transfer mating pair stabilization protein TraN; Provisional.	0
NZ_CP053820.1\|WP_149595617.1\|3004009_3005371_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP053820.1\|WP_032481337.1\|3002218_3002587_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	3.3368e-14
NZ_CP053820.1\|WP_063691927.1\|2997154_2997688_+\|regulator	gnl\|CDD\|377635	pfam06252, DUF1018, Protein of unknown function (DUF1018). This family consists of several bacterial and phage proteins of unknown function.	0.0020516
NZ_CP053820.1\|WP_113604264.1\|2990748_2992173_+\|conjugal-transfer-protein-TraH	gnl\|CDD\|368759	pfam06122, TraH, Conjugative relaxosome accessory transposon protein. The TraH protein is thought to be a relaxosome accessory component, also necessary for transfer but not for H-pilus synthesis within the conjugative transposon.	3.87993e-98
NZ_CP053820.1\|WP_000505208.1\|3008798_3009470_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.50928e-75
NZ_CP053820.1\|WP_063691921.1\|3000908_3001862_+\|replication-protein	gnl\|CDD\|309782	pfam04796, RepA_C, Plasmid encoded RepA protein. Family of plasmid encoded proteins involved in plasmid replication. The role of RepA in the replication process is not clearly understood.	1.76848e-30
NZ_CP053820.1\|WP_000593848.1\|3008064_3008802_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	6.92409e-143
NZ_CP053820.1\|WP_175246303.1\|2992176_2995581_+\|conjugal-transfer-protein-TraG-N-terminal-domain-containing-protein	gnl\|CDD\|369594	pfam07916, TraG_N, TraG-like protein, N-terminal region. The bacterial sequences found in this family are similar to the N-terminal region of the TraG protein. This is a membrane-spanning protein, with three predicted transmembrane segments and two periplasmic regions. TraG protein is known to be essential for DNA transfer in the process of conjugation, with the N-terminal portion being required for F pilus assembly. The protein is thought to interact with the periplasmic domain of TraN to stabilize mating-cell interactions.	1.00951e-56
NZ_CP053820.1\|WP_000683499.1\|3009547_3010294_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270427	cd13709, PBP2_YxeM, Substrate binding domain of an ABC transporter YxeMNO; the type 2 periplasmic binding protein fold. This group contains cystine-binding domain (YxeM) of a periplasmic receptor-dependent ATP-binding cassette transporter and its closely related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.78391e-123
NZ_CP053820.1\|WP_000044781.1\|3007685_3007823_-\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	1.21493e-11
NZ_CP053820.1\|WP_001884349.1\|3007316_3007673_-\|ribonuclease-P-protein-component	gnl\|CDD\|179327	PRK01732, rnpA, ribonuclease P; Reviewed.	2.22129e-65
NZ_CP053820.1\|WP_000378235.1\|3005464_3007090_-\|membrane-protein-insertase-YidC	gnl\|CDD\|234942	PRK01318, PRK01318, membrane protein insertase; Provisional.	0
NZ_CP053820.1\|WP_032481345.1\|3002583_3003807_-\|site-specific-integrase	gnl\|CDD\|271185	cd01185, INTN1_C_like, Integrase IntN1 of Bacteroides mobilizable transposon NBU1 and similar proteins, C-terminal catalytic domain. IntN1 is a tyrosine recombinase for the integration and excision of Bacteroides mobilizable transposon NBU1 from the host chromosome. IntN1 does not require strict homology between the recombining sites seen with other tyrosine recombinases. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.04278e-51
NZ_CP053820.1\|WP_001886301.1\|3007092_3007350_-\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	5.83497e-39

>NZ_CP053820.1|WP_063691921.1|3000908_3001862_+|replication-protein
MKPFSQLLAQYQADIEVENRDKSQGLSRAESELIDASVRIKSDPPSPNDFTFMHSIMCQVGLPRSRVNGSEFERRCGAAGLYIRAGKIWDGKQFLQQPVPYGPMPRLVMAYLNTQALRSKSPEIDVGNSASAFLKQLGKESSGGKNGSYTNFRKQLLALSACSITLGFSTADKAFTYDGKPIQKFEAWIGNSDNQGALWPGVITFSHEYFTTLSEHAVPLDLRALNQLNSSALAMDIYAMLSDRLHRISGRPVVLYWRNLREQFGQEYTGDDADRNFKKVFLPALKRVLTVYPDAKVKKVTGGILMMSSPPPIPYRN
>NZ_CP053820.1|WP_154113085.1|2997784_3000544_+|conjugal-transfer-mating-pair-stabilization-protein-TraN
MSTMPPIMTRFVASLLCLTISVLPIHSYAGNQEPNIGAVGRDAKQFGLSIANGVKQNSAQVQDGKISLPVGNGQSTSININELFPGVQPGQNTAEYFPDAASPEELEQIFSDADAMDQFGNEAKANLFQDANSSNPSISGSAYQVLMDAANRSRPDFSNDPVLNLSKKTYEDMDLIAGGFGDCSAETTINQNTINAHIPEYERCQRVVDQSADCEVVHDYDASVVKHYDGPYNLKSCGDGCTELWIGKVGDDYWAGNCKIYEEYTRVQVSNPDAIVSATLEYVKWDDYMQVWVGKSGQETKVWSGPDGNFPPETAGRCELSTSWERNPNVDVTPYFKNVKDGDVVTFKIRVSVTGEGEGFGRIKLRYDPSKAITKDEWAPQSCMDSAKGVVDGFAEGEITCIDDPTDATGCTVINGVKVCESQLKPSPFPGIPKLCKKVRVKADYDFYKGQMDCWTDPQGETHCPVNTGGNLNSCQMYEDNPQCGFISSECIDGAEGSSGKCYVFKDTYDCGTDISIPTLEKETTYQCGGPIRCMGDDCLDITKSQSTDFARASALLNAAQFMTQDMSCTGQNDDDNPTGEENVMCSAFAGEAGECKIAVGGVSDCCEKPTNISFADYLNLIMAVPKLDGAVMGLSDGSAVKGAYQVLRDPVMSGWTEITQPFASYIENISGAVDSFLQPVQQFAQEAIGALKEQITKLTSEALGNASATGAAGVPAGAPESMTEQILGQQGAAMLSTVMTVYTVYVVSMVMIQMIWKCEEKEFTMNAKRALNSCTYVGSYCKSKVLGACVEERESYCCFNSPLSRIIQEQVRPQLGLNFGDARTPQCGGIPLDRIADIDWSKVNLDEWLGILQQNGKLPDPASLNLDALTGAGSDFNIDGTRQDASERIMERLEGINVDKIRNDKAREIFPDLDGNGG
>NZ_CP053820.1|WP_063691927.1|2997154_2997688_+|regulator
MSECFTSGSLSRWVKARHMALAGYITKIIILETGLTYKQVRRLYAELEYSGYDVKDKKSRTFRGGATLIHSQTSKIQASLLMQLYSNLGGEKVKRSVDISALNKAFRMYHAIRKEVPGMKGGKWEPFDITDAWCLASELRNGEAMIEHCEQCQCTFFTSINQRTCVECPFCRVSKAA
>NZ_CP053820.1|WP_001747910.1|2996540_2997152_+|hypothetical-protein
MYALEPLERDVIGSFDKFAVQLSEEKPDQDIFEFDLTLWTLLKLLSANAPSQVSNHFSLPEDLVNKLASTPDSYLSQLASGVLLSFKLETDQMEVIDALAGSYDSVICLKNVVDDFDAAYWLLLNKLASRNLDMARQNFGVSSGLASSVAASSNSQLRSLSHRVVIRFSLRFDIGVLDQFLSAALADTTPILLKKIQQSLVWR
>NZ_CP053820.1|WP_175246303.1|2992176_2995581_+|conjugal-transfer-protein-TraG-N-terminal-domain-containing-protein
MDFSIYSVGDAAFLEQIMIAVAMATGTGDFERMVSIGLLIGALIISFQSLFQGAKSWDLHQVFACWLVYAISFGAGVTVTIEDAYNGQVRVVDNVPVGPAAAGSIISSVGFGLTKLFEVAYSPVASVTESKFMDSLELLSKLRNHEMESALWTAWNDSLGGGAVDMKKSLTNYISECTAIKFSLGESNEDQINTENWRTALRFDSQIYGTRLFLSPSGPTDPSCTDGWIQLSQSFETAFNSGLSQQALGYLLSTTDALNATSDALYRLQVTNVAAGDFIKANFLQPIVQRGFAQYYSDMNDPYAQIMLTQAESQRNTQYAAEQSLFVKSIQPLMTLVEGFAYAITPIAAFVMVLGSKGLLLVGKYLQMLIWVQLWLPIMSVINLFIYIMGQQALAKYTTGNLSSFEGVAYAGAEIERWIGIGGMMAAATPVLSLMLVTGSVYAFNSLAQRVGASDTVNEKLMSPDLVDRGSVLSQQPQFNQSRIAGTMTSGGESLVDSINLGSTVSNALSSSSAATAQAQKGFASQLSNSVFSGHGSEQTYSQLQSLGQTLRASDSTQAKSILSAAQNYVTDRGINASHTDAVAGAIAMRASAGVDAGKLAAAFTGPVGAAVNAANPVSMNGSLDVSAQSQSQDSRQQLSSDIDSLSRGLGFTKDDSSALTSDLARQVSTDKGQRFTQSLGEEQRKQLMQSSSDLLSSQQTYQELSQAQQTIGTTSNNNISALADKVLNNWSAGKSLSDGVRQSSPETRDFAQRKAQHYQDLGIDSQRAIVGGQLFAMLNSNSPSEQAIAASAIAKATGGNSGIDFNQPGQSAMLVKDAPRYVSPVENSSALSAPERMSNEQKLLAESGSIGSENSVRDAHEKGIQQLEQSYGTSRNEYLNDRLPALRAQIMASDLAPSTSSALFAGAEGAGRFVQQVVGGAGAAKEGFAESFGQSMSKLAQMTPEQRDQFIEDTKKGDDYVKQEYGLGGFLAVGAANLGRDIIGVGISGFEAGKEWLTGKSDLSEAAQGMSVRERGMFFASALASASEAGAGKAAEFVQQYGDEFRQIAMDTARYDYGLNSQAGAELFAASLMGGDSSRSGELRENLREEVGDNVLADKMAAIIESSAGAGKDQAGGYLAPVSRYLSVAKGGR
>NZ_CP053820.1|WP_113604264.1|2990748_2992173_+|conjugal-transfer-protein-TraH
MRVSPPYIRTLSASCLIIFSVVATHASAEGLQSEMDRLFNEMSNTTRPGIHETQRRGVIAGGRVTTKARIFDENLVSFVPPSWKAGCGGVDLFGGSLSFVNADQIVQLMRAVAANAKGYAFQLALDNVFPDGAKWIENFQKKVQALNQHLGNSCQLAQGIVNDSLSAFDTKLKNDTRTKASTKGLFEDMFSATQETDGQTAIKTLKDNSPQAYQEMIGNIVWKQLKKNSVSSWFQYGDNSLLEAMMSITGAVVIGDLINDPNLAGANNSTNPIVTLPGNRITLGDLISGGSVKVYSCDSDTVNCISAGSELKSVQLRGIGNQMSDLLLGSDSSPGLIYKYANNVGALSSAEIAFVSNLPSSFGSLFRNLAAVSSDTAEQFAQQAQTIIALDITYRFIEEIYRATTIALANSDNAYQQKAVDVLDASRAVVRQEYDQLIVRHGKLSDLMGYYNSLLDVTKKQRLLLAAQASGKKE
>NZ_CP053820.1|WP_113604263.1|2989647_2990505_-|hypothetical-protein
MKMNMSTTVSSATALFAAIMLAGCATTPKSYNSDMSRALNLARVGGIYDQDLRDSEDGQNSYRQSLLMKALNVTSLASSLDAPLRGLNGQQTLMFNTASILTSPDNPSARPSLMAWMPASMAKSSEDAYSNYINLIDNAVAVAAKSMNLDLTKIVESTAPKIDGNPLIMWAVTAPQFGCDGSNCVIAYNVTMPNPWKTPAFVGSGIIDSFNLAANNTTKYSRLIFTQVSDVKSFPMDDFYKSTSRALPEWAVMYFPPNSVFQDGKALPYPVIYEKGQQLLFRKAQ
>NZ_CP053820.1|WP_011791301.1|2989255_2989651_-|hypothetical-protein
MSLWHEELELALLNLEDSKASCDVMTYVISHILAKSDIPHQCRVGFVETVHSKTQINPHCWIELKDGWGIDLTLRRWLGDEDRWPHGVFRLSDYPQVQFWGTPLFAPKLDDEEINAMSDHLIETVKIPVCC
>NZ_CP053820.1|WP_000901446.1|2988571_2988841_+|hypothetical-protein
MLGQNQTEIHQFDVCGRVYYRGVNYTEKEGELAVETVEATSHDEAEALFKSLQDEYARECNRTVERIDITFTIDLTIAESDNDEPYLVM
>NZ_CP053820.1|WP_001747916.1|2988308_2988494_+|hypothetical-protein
MYRLILTNQKKRTREYQPSDAGYRAALKATRKFLEQNPQGNAVLYGHGVCESFTIRNMPEA
>NZ_CP053820.1|WP_032481337.1|3002218_3002587_+|helix-turn-helix-domain-containing-protein
MTVDVNETLNALRSEIAEMKQLLAQFVENTVSDGSKSNLPPSDKEYFTVDEAAAYVGAKRSYIYRLTHEKRLSFTKPGGNRVLIKRSDLQAWLEKNRVKSADELHQDVANYITSFPRGRKAS
>NZ_CP053820.1|WP_032481345.1|3002583_3003807_-|site-specific-integrase
MKVSVNKRNPNSKGLQQLRLVYYYGVVEGEDGKKRPKRDYEPLELYVYQNPKTQAERQHNKEMLRQAEAARSARLVESHANKFQLEDRVKLASSFYEYYDRLTSTKEPGSTSNYSIWVSAGKHLRSYHGRAELTFEEIDKKFLEGFRKYLLEEPLTKSKSKLAKNTASSYFNKVRAALNEAYREGIIRDNPVQRVKSVKAENTKRTYLTLDEVRAMTKAECRYDVLKRAFLFSCTTGLRWSDINKLTWSEIEEFEPGHYRIIFDQQKLKNGGNSLVYLDLPDSAVTLLNIQNREGPDDRVFVGLKYNSYMNVALLQWAMRAGITKHVTFHAGRHTFAVAQLNRGVDIYSLSRLLGHSELRTTEIYADILESRRVTAMRGFPDIFEDKVKESGACCPHCGKSVMNKTL
>NZ_CP053820.1|WP_149595617.1|3004009_3005371_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MTTDTIVAQATAPGRGGVGIIRVSGPLAAHVAQTVTGRTLRPRYAEYLPFTDEDGQQLDQGIALFFPNPHSFTGEDVLELQGHGGPVVMDMLIRRILQIKGVRPARPGEFSERAFLNDKMDLTQAEAIADLIDASSEQAAKSALQSLQGEFSKRIHTLVESLIHLRIYVEAAIDFPEEEIDFLADGKVSADLQTIIDNLAAVRREANQGAIMREGMKVVIAGRPNAGKSSLLNALSGKESAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDASDAVEKIGIERAWEEIRQADRVLFMVDGTTTEATDPQDIWPDFVDKLPENIGITVIRNKADQTGEPLGICHVNQPTLIRLSAKTGQGVDALRQHLKECMGFSGNQESGFMARRRHLDALERAAEHLAIGQQQLEGYMAGEILAEELRIAQQHLNEITGEFSSDDLLGRIFSSFCIGK
>NZ_CP053820.1|WP_000378235.1|3005464_3007090_-|membrane-protein-insertase-YidC
MDSQRNILLIALALVSFLLFQQWQVAKNPAPQATQQAQSTGAAPAPSFSDELDPTPAQNVAAKAKTITVSTDVLTLSIDTLGGDVVSAKLNQYSEELNSPESFVLLQNTQGHQFIAQSGLVGPQGIDVTSNNRPAYQVSADSFTLAEGQDELRIPMTYQANGIDYTKTFILKRGSYAVDVVFDVANNSGSEATLGMYAHLRQNLLDSGGNLAMPTYRGGAYSTSDVRYKKYSFDDMKDRNLSAPNDVTVNWVAMIQHYFASAWIPRDEPQAQLYSRVINNLGDMGIRTPNKTIANGDKAEFEATLWVGPKLQDQMAATAPNLDLVVDYGWLWFIAKPLHWLLSVIQTFVGNWGVAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQRMSQEMMELYKKEKVNPLGGCLPILLQMPIFIALYWALMESVELRHSPFFGWIHDLSAQDPYYILPLLMGASMFVIQKMSPTTITDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQTLIYKALEKKGLHSK
>NZ_CP053820.1|WP_001886301.1|3007092_3007350_-|membrane-protein-insertion-efficiency-factor-YidD
MATPLSPFSWLAIGIVKLYQWFISPLIGPRCRFTPTCSTYAIEALRAHGFIKGCWLSTKRLLKCHPLNEGGFDPVPPVQKQDRDK
>NZ_CP053820.1|WP_001884349.1|3007316_3007673_-|ribonuclease-P-protein-component
MSTYAFNRELRLLTPEHYQKVFQQAHSAGSPHLTIIARANNLSHPRLGLAVPKKQIKTAVGRNRFKRICRESFRLHQNQLANKDFVVIAKKSAQDLSNEELFNLLGKLWQRLSRPSRG
>NZ_CP053820.1|WP_000044781.1|3007685_3007823_-|50S-ribosomal-protein-L34
MSKRTFQPSVLKRKRTHGFRARMATANGRKVLNARRAKGRKRLSK
>NZ_CP053820.1|WP_000593848.1|3008064_3008802_-|amino-acid-ABC-transporter-ATP-binding-protein
MIKLQNIHKRFGTSEVLKGIDLEIQRGEIVVIIGSSGTGKSTLLRCVNFLEQADQGSIRIDELTVDTHKHTKVDVLALRRKTGFVFQNYALFAHLTARQNIAEALITVRGWKKAQAHQRAQQILDDIGLGDKGDSYPAALSGGQQQRVGIGRAMALQPELLLFDEPTSALDPEWVGEVLALMKKLATQHQTMLVVTHEMQFAKEVADRVIFMAEGKIVEQGSPQDIFDHPQDPRLRKFLNQVGIR
>NZ_CP053820.1|WP_000505208.1|3008798_3009470_-|amino-acid-ABC-transporter-permease
MGFDFHYMLELLPILLKYLGTTLEMASWGLVFALILALILANIRVFKVPVLDPLSQLYISFFRGTPLLVQLFLLYYGLPQVFPLLVGLDAFSAAVIGLTLHFAAYMAESIRAAIIGIDRSQMEASLSVGMTTSQAMRRIILPQATRVALPSLMNYFIDMIKSTSLAFTLGVAEIMAKAQMEASSSFRFFEAFLAVALIYWVVVLVLTRLQSWAEQKLNKAYAR
>NZ_CP053820.1|WP_000683499.1|3009547_3010294_-|amino-acid-ABC-transporter-substrate-binding-protein
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRNDYKVEFVTANFSGLFGLLETGRIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEAIKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDTGIEHDVALGRADAFVMDRLSALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALKWFGTDISQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	NZ_CP053818	Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence	16184-16215	1	0.969
NZ_CP053820_1	1.4\|1954944\|33\|NZ_CP053820\|CRISPRCasFinder	1954944-1954976	33	NZ_CP053818	Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence	16183-16215	2	0.939
NZ_CP053820_2	2.1\|2576727\|37\|NZ_CP053820\|PILER-CR	2576727-2576763	37	NC_049942	Escherichia phage JLK-2012, complete sequence	23524-23560	4	0.892
NZ_CP053820_2	2.1\|2576727\|37\|NZ_CP053820\|PILER-CR	2576727-2576763	37	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35428-35464	4	0.892
NZ_CP053820_1	1.1\|1954885\|32\|NZ_CP053820\|PILER-CR	1954885-1954916	32	AM087120	Acidianus filamentous virus 3, partial viral genome	7011-7042	8	0.75
NZ_CP053820_1	1.3\|1954884\|33\|NZ_CP053820\|CRISPRCasFinder	1954884-1954916	33	AM087120	Acidianus filamentous virus 3, partial viral genome	7011-7043	9	0.727
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	AC171169	Escherichia virus H8 clone h8_phage, WORKING DRAFT SEQUENCE	37912-37943	10	0.688
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	NC_031022	Shigella phage SHSML-45, complete genome	74110-74141	10	0.688
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	NC_028754	Salmonella phage Shivani, complete genome	48716-48747	10	0.688
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	NC_042307	Escherichia virus H8, complete genome, * SEQUENCING IN PROGRESS *	37912-37943	10	0.688
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	LR597659	Escherichia phage T5_ev212 genome assembly, chromosome: 1	52289-52320	11	0.656
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	AP019559	Escherichia phage SP15 DNA, complete genome	50737-50768	11	0.656
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	MN445182	Salmonella phage vB_SalS_SA001, complete genome	48037-48068	11	0.656
NZ_CP053820_1	1.2\|1954945\|32\|NZ_CP053820\|PILER-CR	1954945-1954976	32	MN022787	Salmonella virus VSe12, complete genome	52087-52118	11	0.656

1. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to NZ_CP053818 (Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence) position: , mismatch: 1, identity: 0.969

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
gcgtaatgaatccactggtgaaatgggctggc	Protospacer
********** *********************

2. spacer 1.4|1954944|33|NZ_CP053820|CRISPRCasFinder matches to NZ_CP053818 (Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence) position: , mismatch: 2, identity: 0.939

gcgtaatgaagccactggtgaaatgggctggct	CRISPR spacer
gcgtaatgaatccactggtgaaatgggctggcg	Protospacer
********** *********************

3. spacer 2.1|2576727|37|NZ_CP053820|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
caggtcgccagttcgattccggtagccggcaccatat	Protospacer
.*********************.***********. *

4. spacer 2.1|2576727|37|NZ_CP053820|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
taggtcaccagttcgattccggtagccggcaccaatc	Protospacer
******.***************.*********** *.

5. spacer 1.1|1954885|32|NZ_CP053820|PILER-CR matches to AM087120 (Acidianus filamentous virus 3, partial viral genome) position: , mismatch: 8, identity: 0.75

cgaccgcaagagttctgctcgcgcttggtgaa	CRISPR spacer
gctcgacaagagttctgctgtcgcttggtgac	Protospacer
   * .*************  **********

6. spacer 1.3|1954884|33|NZ_CP053820|CRISPRCasFinder matches to AM087120 (Acidianus filamentous virus 3, partial viral genome) position: , mismatch: 9, identity: 0.727

cgaccgcaagagttctgctcgcgcttggtgaat	CRISPR spacer
gctcgacaagagttctgctgtcgcttggtgacc	Protospacer
   * .*************  ********** .

7. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to AC171169 (Escherichia virus H8 clone h8_phage, WORKING DRAFT SEQUENCE) position: , mismatch: 10, identity: 0.688

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttacgaaa	Protospacer
 ******. ***************  .* ..

8. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to NC_031022 (Shigella phage SHSML-45, complete genome) position: , mismatch: 10, identity: 0.688

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttacgaaa	Protospacer
 ******. ***************  .* ..

9. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to NC_028754 (Salmonella phage Shivani, complete genome) position: , mismatch: 10, identity: 0.688

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttacgaaa	Protospacer
 ******. ***************  .* ..

10. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to NC_042307 (Escherichia virus H8, complete genome, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 10, identity: 0.688

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttacgaaa	Protospacer
 ******. ***************  .* ..

11. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to LR597659 (Escherichia phage T5_ev212 genome assembly, chromosome: 1) position: , mismatch: 11, identity: 0.656

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttatgaaa	Protospacer
 ******. ***************  .. ..

12. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to AP019559 (Escherichia phage SP15 DNA, complete genome) position: , mismatch: 11, identity: 0.656

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttatgaaa	Protospacer
 ******. ***************  .. ..

13. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to MN445182 (Salmonella phage vB_SalS_SA001, complete genome) position: , mismatch: 11, identity: 0.656

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttatgaaa	Protospacer
 ******. ***************  .. ..

14. spacer 1.2|1954945|32|NZ_CP053820|PILER-CR matches to MN022787 (Salmonella virus VSe12, complete genome) position: , mismatch: 11, identity: 0.656

gcgtaatgaagccactggtgaaatgggctggc	CRISPR spacer
tcgtaatatagccactggtgaaatttatgaaa	Protospacer
 ******. ***************  .. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

675702 : 682319

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000210573.1\|675702_676836_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4
WP_002044486.1\|676847_678098_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	3.9e-100	49.5
WP_000543544.1\|678197_678647_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_175245939.1\|678672_679776_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.0e-44	33.3
WP_071193055.1\|679780_680434_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.0e-32	38.7
WP_123011119.1\|680474_681584_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_123011118.1\|681848_682319_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.9e-34	48.0

DBSCAN-SWA_2

2275777 : 2282970

Anguillid_herpesvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162850.1\|2275777_2276206_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4
WP_001959105.1\|2276409_2277699_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	6.5e-34	34.0
WP_000872174.1\|2277918_2278113_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_001124187.1\|2278161_2278500_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_001959107.1\|2278513_2280364_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.5e-105	40.9
WP_001105750.1\|2280387_2280903_-	co-chaperone HscB	NA	NA	NA	NA
WP_000301571.1\|2280951_2281275_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_000331703.1\|2281335_2281719_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_175246178.1\|2281755_2282970_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	2.0e-32	30.5

DBSCAN-SWA_3

2516054 : 2523279

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001914090.1\|2516054_2516942_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	2.4e-56	41.1
WP_071179763.1\|2517209_2519798_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	4.9e-33	23.2
WP_123011330.1\|2519891_2520899_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	7.8e-35	34.2
WP_000177559.1\|2520972_2521908_-	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_057550676.1\|2521907_2522534_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	51.5
WP_000698379.1\|2522526_2523279_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3

DBSCAN-SWA_4

2833741 : 2840470

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033933084.1\|2833741_2835079_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	8.5e-05	25.5
WP_033933083.1\|2835068_2835884_-	ABC transporter permease	NA	NA	NA	NA
WP_000864155.1\|2835888_2836440_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.0e-53	60.5
WP_029628155.1\|2836439_2837330_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	7.3e-37	34.6
WP_000676094.1\|2837326_2838205_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	4.2e-109	66.9
WP_175246269.1\|2838228_2839293_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.0e-98	51.6
WP_114709324.1\|2839531_2840470_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	4.7e-34	35.2

DBSCAN-SWA_5

2867561 : 2875102

Stx2-converting_phage(33.33%)

integrase

attL 2863218:2863234|attR 2871657:2871673

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2863218:2863234	attL	NA	NA	NA	NA
WP_175246280.1\|2867561_2868818_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1W6JPG6	Morganella_phage	4.8e-74	38.8
WP_175246281.1\|2868819_2869158_+	hypothetical protein	NA	NA	NA	NA
WP_075607785.1\|2869354_2869657_+	type II toxin-antitoxin system HigB family toxin	F5A3A2	Riemerella_phage	8.9e-11	33.0
WP_000354815.1\|2869688_2870060_+	transcriptional regulator	A0A222YXG1	Escherichia_phage	1.2e-30	56.4
WP_175246282.1\|2870085_2872512_+	DEAD/DEAH box helicase family protein	G0T5H3	Wiseana_iridescent_virus	9.3e-26	27.0
2871657:2871673	attR	NA	NA	NA	NA
WP_095481607.1\|2873605_2874808_-	ImmA/IrrE family metallo-endopeptidase	A0A0P0ZCT8	Stx2-converting_phage	7.6e-29	57.4
WP_001197622.1\|2874817_2875102_-	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	1.7e-24	58.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053820

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection