CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP053744	Vibrio cholerae strain SA3G chromosome 1, complete sequence	1 crisprs	RT,cas3,DEDDh,DinG,csx1,WYL,csa3	0	1	6	0
NZ_CP053745	Vibrio cholerae strain SA3G chromosome 2, complete sequence	0 crisprs	csa3,cas3	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP053744_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP053744_1

2597780-2598023

Orphan

Consensus_repeat	Method
AAAATGTGCCTCCTTAGCTCAGTCGGTAGAGCAACGGACTGATAATCCG	PILER-CR

2 spacers

The CRISPR arrays of NZ_CP053744_1

>merge|NZ_CP053744|1|2597780-2598023|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGGTCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAATTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTGTCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAATTGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

>NZ_CP053744|1|1|2597780-2598023|PILER-CR
TGTGCCGGCTTAGCTCAGTAGGTAGAGCAACTGACTTGTAATCAGTAGG	TCGCCAGTTCGATTCCGGCAGCCGGCACCACTTAAAA
TTTGCCTCGATAGCTCAGTCGGTAGAGCAGAGGATTGAAAATCCTCGTG	TCGGTGGTTCGATTCCGCCTCGAGGCACCACTATTAAAAGTTGTGCCATAGACACAATAAAAAT
TGTTCCTCCTTAGCTCAGTCGGTAGAGCGACGGACTGTTAATCCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP053744.1\|WP_001243262.1\|2606693_2607509_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NZ_CP053744.1\|WP_000035022.1\|2607971_2608781_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	unknown	unknown	gnl\|CDD\|234673
NZ_CP053744.1\|WP_001233675.1\|2590475_2590907_+\|DUF4426-domain-containing-protein	unknown	unknown	gnl\|CDD\|379616
NZ_CP053744.1\|WP_000805054.1\|2592982_2593903_-\|glutaminase-B	unknown	unknown	gnl\|CDD\|234880
NZ_CP053744.1\|WP_175249136.1\|2598314_2599940_+\|cache-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP053744.1\|WP_175249135.1\|2596421_2597549_+\|membrane-bound-lytic-murein-transglycosylase-MltC	unknown	unknown	gnl\|CDD\|183271
NZ_CP053744.1\|WP_175249134.1\|2591572_2592748_+\|radical-SAM-family-heme-chaperone-HemW	unknown	unknown	gnl\|CDD\|235550
NZ_CP053744.1\|WP_000954087.1\|2609440_2609914_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|182143
NZ_CP053744.1\|WP_000725008.1\|2590976_2591579_+\|XTP/dITP-diphosphatase	unknown	unknown	gnl\|CDD\|234648
NZ_CP053744.1\|WP_001277601.1\|2601998_2604350_+\|LPS-assembly-protein-LptD	unknown	unknown	gnl\|CDD\|235158
NZ_CP053744.1\|WP_175249133.1\|2589582_2590140_+\|YggT-family-protein	unknown	unknown	gnl\|CDD\|223833
NZ_CP053744.1\|WP_000546924.1\|2600985_2601840_-\|co-chaperone-DjlA	unknown	unknown	gnl\|CDD\|236512
NZ_CP053744.1\|WP_000741914.1\|2590139_2590430_+\|YggU-family-protein	unknown	unknown	gnl\|CDD\|179931
NZ_CP053744.1\|WP_001888163.1\|2594972_2596034_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|182805
NZ_CP053744.1\|WP_000124738.1\|2596047_2596320_+\|oxidative-damage-protection-protein	unknown	unknown	gnl\|CDD\|180059
NZ_CP053744.1\|WP_102786370.1\|2605687_2606680_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	unknown	unknown	gnl\|CDD\|234696
NZ_CP053744.1\|WP_102786367.1\|2608930_2609428_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_CP053744.1\|WP_000005581.1\|2594013_2594733_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl\|CDD\|234649
NZ_CP053744.1\|WP_102786369.1\|2607580_2607961_+\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NZ_CP053744.1\|WP_000780522.1\|2604402_2605698_+\|peptidylprolyl-isomerase-SurA	unknown	unknown	gnl\|CDD\|236758

Protein	Function_ID	Function_description	E-value
NZ_CP053744.1\|WP_001243262.1\|2606693_2607509_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	3.27746e-146
NZ_CP053744.1\|WP_000035022.1\|2607971_2608781_+\|symmetrical-bis(5'-nucleosyl)-tetraphosphatase	gnl\|CDD\|234673	PRK00166, apaH, symmetrical bis(5'-nucleosyl)-tetraphosphatase.	5.07117e-169
NZ_CP053744.1\|WP_001233675.1\|2590475_2590907_+\|DUF4426-domain-containing-protein	gnl\|CDD\|379616	pfam14467, DUF4426, Domain of unknown function (DUF4426). Members of this entry are found mostly in g-proteobacteria, especially in Vibrio. Strangely enough, there seems to be one eukaryotic homolog in Nematostella vectensis (NEMVEDRAFT_v1g226006), where the PA0388-like domain is fused with a domain homogous to the Methionine biosynthesis protein MetW (see below). In several Pseudomonas species, but also in Vibrio vulnificus and Azotobacter vinelandii PA0388 homologs are genomic neighbors of Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) and Methionine biosynthesis protein MetW. On the other hand, in most Vibrio species it appears as a part of a conserved operon involved in possible response to stress.	5.78532e-66
NZ_CP053744.1\|WP_000805054.1\|2592982_2593903_-\|glutaminase-B	gnl\|CDD\|234880	PRK00971, PRK00971, glutaminase; Provisional.	0
NZ_CP053744.1\|WP_175249136.1\|2598314_2599940_+\|cache-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	5.04451e-57
NZ_CP053744.1\|WP_175249135.1\|2596421_2597549_+\|membrane-bound-lytic-murein-transglycosylase-MltC	gnl\|CDD\|183271	PRK11671, mltC, membrane-bound lytic murein transglycosylase MltC.	5.28801e-156
NZ_CP053744.1\|WP_175249134.1\|2591572_2592748_+\|radical-SAM-family-heme-chaperone-HemW	gnl\|CDD\|235550	PRK05660, PRK05660, radical SAM family heme chaperone HemW.	0
NZ_CP053744.1\|WP_000954087.1\|2609440_2609914_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|182143	PRK09917, PRK09917, threonine/serine exporter.	7.45224e-67
NZ_CP053744.1\|WP_000725008.1\|2590976_2591579_+\|XTP/dITP-diphosphatase	gnl\|CDD\|234648	PRK00120, PRK00120, dITP/XTP pyrophosphatase; Reviewed.	5.88466e-128
NZ_CP053744.1\|WP_001277601.1\|2601998_2604350_+\|LPS-assembly-protein-LptD	gnl\|CDD\|235158	PRK03761, PRK03761, LPS assembly outer membrane complex protein LptD; Provisional.	0
NZ_CP053744.1\|WP_175249133.1\|2589582_2590140_+\|YggT-family-protein	gnl\|CDD\|223833	COG0762, COG0762, Predicted integral membrane protein [Function unknown].	5.30724e-12
NZ_CP053744.1\|WP_000546924.1\|2600985_2601840_-\|co-chaperone-DjlA	gnl\|CDD\|236512	PRK09430, djlA, co-chaperone DjlA.	1.60415e-153
NZ_CP053744.1\|WP_000741914.1\|2590139_2590430_+\|YggU-family-protein	gnl\|CDD\|179931	PRK05090, PRK05090, hypothetical protein; Validated.	1.27614e-60
NZ_CP053744.1\|WP_001888163.1\|2594972_2596034_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|182805	PRK10880, PRK10880, adenine DNA glycosylase.	0
NZ_CP053744.1\|WP_000124738.1\|2596047_2596320_+\|oxidative-damage-protection-protein	gnl\|CDD\|180059	PRK05408, PRK05408, oxidative damage protection protein; Provisional.	5.47988e-59
NZ_CP053744.1\|WP_102786370.1\|2605687_2606680_+\|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA	gnl\|CDD\|234696	PRK00232, pdxA, 4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed.	0
NZ_CP053744.1\|WP_102786367.1\|2608930_2609428_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	3.0845e-91
NZ_CP053744.1\|WP_000005581.1\|2594013_2594733_-\|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.57395e-111
NZ_CP053744.1\|WP_102786369.1\|2607580_2607961_+\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	1.87762e-74
NZ_CP053744.1\|WP_000780522.1\|2604402_2605698_+\|peptidylprolyl-isomerase-SurA	gnl\|CDD\|236758	PRK10770, PRK10770, peptidyl-prolyl cis-trans isomerase SurA; Provisional.	1.14348e-156

>NZ_CP053744.1|WP_175249135.1|2596421_2597549_+|membrane-bound-lytic-murein-transglycosylase-MltC
MRKLVLCITALLLSGCSREFIEKIYDVDYEPTNRFAKNLAELPGQFQKDTAALDALINSFSGNIEKRWGRSELKIAGKNNYVKYIDNYLSRSEVNFTEGRIIVETVSPIDPKAHLRNAIITTLLTPDDPAHVDLFSSKDIELKGQPFLYQQVLDQDGQPIQWSWRANRYADYLIANHLKVKQVDFKKAYYVEIPMVKDQIDIRGYKYASIVRKASRKYDIPEDLIYAIIKTESSFNPYAVSWANAYGLMQVVPKTAGRDVFKLVKNRSGEPTPEYLFNPENNIDTGTAYFYILKNRYLKEVRHPTSLEYSMISAYNGGTGGVLSTFSSDRQRAMRDLNALQPNQVYWALTKKHPNAEARRYLEKVTKFKKEFNAG
>NZ_CP053744.1|WP_000124738.1|2596047_2596320_+|oxidative-damage-protection-protein
MARTVFCTRLQKEADGLDFQLYPGELGKRIFDNICKEAWAQWQTKQTMLINEKKLNMMDPEHRKLLEQEMVNFLFEGKEVHIEGYTPPAK
>NZ_CP053744.1|WP_001888163.1|2594972_2596034_+|A/G-specific-adenine-glycosylase
MTPFAQAILTWYDAYGRKNLPWQQNKNAYRVWLSEIMLQQTQVATVIPYFERFLERFPTVQALAAAPQDEVLHFWTGLGYYARARNLHKAAQMVVSEYGGEFPTDLEQMNALPGVGRSTAAAVLSSVYKKPHAILDGNVKRTLARCFAVEGWPGQKSVENQLWHYAEMHTPKVDVDKYNQAMMDMGAMICTRSKPKCSLCPVESFCLAKQQGNPQEYPGKKPKTEKPVKATWFVMLYHDNAVWLEQRPQSGIWGGLYCFPQSEIANIQTTIDQRAIGDSTITSQKTLIAFRHTFSHYHLDITPILLQLSRKPDIVMEGSKGLWYNLSQPDEIGLAAPVKQLLHSLPFDIDSHI
>NZ_CP053744.1|WP_000005581.1|2594013_2594733_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MSEVITQEYTEDGKVLRRIRSFVRREGRLTKGQEAAMKECWPTMGIDYQPELLDWQQVFGNDNPVVLEIGFGMGASLVEMAKNAPEKNFLGIEVHSPGVGACLASAREAGVTNLRVMCHDAVEVFAHMIPDNSLHTLQLFFPDPWHKKRHHKRRIVQLEFAEMVRQKLIIGSGVFHMATDWENYAEHMIEVMNQAPGFANLATDGDYIPRPDERPLTKFEQRGHRLGHGVWDIKYQRTA
>NZ_CP053744.1|WP_000805054.1|2592982_2593903_-|glutaminase-B
MKPTAEILASIIEEVRPLTGQGKVADYIPALAKVPSEKLGIAVFTNQGEVISAGDAQEGFSIQSISKVLSLTLAMGLYQPDELWSRVGKEPSGQAFNSLIQLEMEQGIPRNPFINAGAIVVCDMLQSRLSAPRQRLLEFVRQLSGEPLIAYDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSKQTNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIIAVVPGEMTIAVWSPALDQSGNSLAGTRALELLAQRIGRSIF
>NZ_CP053744.1|WP_175249134.1|2591572_2592748_+|radical-SAM-family-heme-chaperone-HemW
MLTPPPLSLYIHIPWCVQKCPYCDFNSHAQKGEIPEQEYLDALLEDLDRDIERYQLKGDPRLLHSIFIGGGTPSLISAEGIARLLQGVAERIAFKPEIEITMEANPGTIEAQRFAGYRTAGVTRISIGVQSFEPEKLARLGRIHGQQEAVRAAQLAHKIGLNSFNLDLMHGLPDQTPEQALADLDQAIALNPPHLSWYQLTIEPNTLFYSKPPKLPDEDALWDIFELGHQKLSDAGYVQYEISGYSKPGYQCQHNLNYWRFGDYLGIGCGAHGKLSFADGRIVRTTKTKHPRGYLAALNNLAKAYLDSEQLVADQDKPFEFFMNRFRLIEPCPKADFTATTGLTIDVIRPTLDWAISEGYLSEDDQHWQITEKGKLFLNDLLEAFMADEEE
>NZ_CP053744.1|WP_000725008.1|2590976_2591579_+|XTP/dITP-diphosphatase
MKKIVLATGNQGKVREMADLLSDFGFDVVAQSEFNVPEAAETGTTFIENAIIKARHAAKITGLPAIADDSGLEVDYLNGAPGIYSARYAGEHASDGDNLNKLLAAMQDVPDDQRSARFHCVLVLMRHADDPTPIVCHGKWEGKILTAPHGSNGFGYDPIFWVPEENCASAELEPVRKKQLSHRGKALQKLFKAIEEQRTC
>NZ_CP053744.1|WP_001233675.1|2590475_2590907_+|DUF4426-domain-containing-protein
MRKWMMSLLLTLLALPASAEQQKTIKDIEVHYSAFNSTFLTPKVASSYQLTRNGYTAILNISVLDRASLGKPATEAKLTGHTKNLIGNLRELNFKQVKEGNAIYYLAEVPISNEEMLTFDIDVDAGLKGAGKLTFSQKFYTEQ
>NZ_CP053744.1|WP_000741914.1|2590139_2590430_+|YggU-family-protein
MAAVWREGDDLLLRLYIQPKASRDSIVGLHGEELKVAITAPPIDGKANAHLSKYLAKLCKVAKGSVVIEKGELGRHKQVRILQPSQIPAEIAALIE
>NZ_CP053744.1|WP_175249133.1|2589582_2590140_+|YggT-family-protein
MNSLSFLINTLFDLYIMVVILRIWLQAARADFYNPFSQFIVKATQPVVGPLRRVIPSIGSIDLATIVFAYVLCVLKFMALVLIASSGSVSFSADFLFLGLLSLIKAAGGLLFWVLLIRAILSWVSQGRSPIEYVFHQLTEPMLAPIRRIIPVMGGFDLSILVLFIVLQLANFLMGDVIGPIWYQL
>NZ_CP053744.1|WP_175249136.1|2598314_2599940_+|cache-domain-containing-protein
MKLKTQAYLLSAIILAALLALTATGLWTLRVASNLDNKARVTELFNSAYSILTEVEKLAQEGKMSEPEAKALATRLMRNNLYKDNEYVYVADENMTFVATPLDPQLHDTSFHDFKDGKGNSVGRLIQDVLRHQSGKLVEYTWTQKQADGSIEEKLSIARKTPHWGWVVGTGIGFNEVNARFWSTAQWQLSLCVVIAVAILSLLLVAIRKILLIIGGEPNEVRSAVQAVAQGRIRREFAIQAPKESIYGAVQQMSSSLADLVAKLEQSMVALRSELAGAGTRAKSIAELTDSQQQSTAMIATAMTEMASSANQVADSARDTAFNTDQADQQSQHTQKLIHNTVSNIQGLATQLQTASTAVAELDLDVKNIAKVLVVIGDIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLAGRTQTSTKEIQQMIHNLQEGSRNAIQTIQICGQTSQSSVQESENAASALALIVSALESVSSMSHQIATAAAEQTQVSDDIARRINMIEESGSKLSRVVMESHNSTQTLTKLARELEQWAAHFEVTR
>NZ_CP053744.1|WP_000546924.1|2600985_2601840_-|co-chaperone-DjlA
MHIFGKILGAFFGFLFGGPFGAIFGIFLGHQFDKARRLNQAGFQSGTFGAGPSQAERQEEFFKSAFSVMGHVAKAKGQVTKEEIQLATIMMDRMNLTLEQKRAAQDAFRDGKESDFPLEQVLERVKIATGGRFDLLQFFLELQVSSAFADGDVHPSERQVLHRIARGLGFSSEQLERRLRMQEAAFRFQQGGGFGGSQQQSHSGQQWQQPSSRHQLADAYEVLGVSESASAQEVKRAYRKLMNEHHPDKLMAKGLPPEMMNVAKEKSQQIQHAYELIRKEKGIK
>NZ_CP053744.1|WP_001277601.1|2601998_2604350_+|LPS-assembly-protein-LptD
MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLADDQLHTELGDRWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSDLDSGVGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTKDTTSTNLPYRLMPQLSYNYYAPETMKYLDLDLVSHVSRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVTRVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTLLQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNKNPDSTSDKTSYSAWAVEMDFNFADYLFYHGGIQYDIDSQAVQLGNSTLEYRVASGYIQANYRYVAKDYIRNTVGDSITNIDDITRDGISQAGILAGYQLSRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFTYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
>NZ_CP053744.1|WP_000780522.1|2604402_2605698_+|peptidylprolyl-isomerase-SurA
MKLWKPTLISVLSALTLFNAHAEPKQLDSVAVIVNSGVILQSDVDSALKTIKANAKQNKQPLPQETVLREQVLEKLIIDTLQQQEADRIGVKIDDNRLNEAIKEIAKNNQQTQEQLIASVAQEGLTYPEFREQVRKEMAASDARNALVRRRINILPAEVDTLAELLAQETDATVQYKISHIQLRVDDGQDKSAAETLANKLVNDLRNGADFAQMAYAYSKGPKALQGGDWGWMRKEEMPTIFADQIKMQNKGSIIGPFRSGVGFHILKIDDVKGLETVAVTEVNARHILIKPTIILSDEGAQKQLNEFVQRIKNGEVTFAELAQQYSQDPGSAAQKGELGYQTPDLYVPEFKHQIETLPVGQISEPFKTVHGWHIVEVLDRREVDRTDSALKNKAYRILFNRKFNEEASAWLQELRASAFVEVLKDEKDEQ
>NZ_CP053744.1|WP_102786370.1|2605687_2606680_+|4-hydroxythreonine-4-phosphate-dehydrogenase-PdxA
MSSKRIIVTAGEPAGIGPDLVLALSAQDWPHQLVVCADKALLAQRAAQLGIQVKLLDYQHNNPVQPQQAGTLLVEHIPLAEPVVAGQLNPANGHYVLKTLERAAKGCMNGEFDAIVTGPVHKGVINRAGVAFSGHTEFFAEQSKTPLVVMMLATEGLRTALVTTHLPLAEVPQAITCERLEQIVHILHKDLVEKFAIAEPKIYVCGLNPHAGEDGVLGMEEIETITPTLQRLREQYGMQLVGPLPADTIFSEKYLQQADAVLGMYHDQVLPVLKYKGFGRSVNITLGLPFIRTSVDHGTALDLAGTGQADAGSFWTALAYAIELVDKKAQ
>NZ_CP053744.1|WP_001243262.1|2606693_2607509_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MRNDVHLGHKARKRFGQNFLNDPYIIDGIVSAINPKPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELASKLTIHEGDAMRFDFKQLVKPNNKLRVFGNLPYNISTPLMFHLFEFHRDIQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYYCKVVPVLEVPPSAFVPPPKVDSAVVRLVPYEDLPHPATSLEWLDRVVREGFNQRRKTVRNCYKGLAEPETLETLGINPGMRPENLTLAQFVALANWLDATHKTHA
>NZ_CP053744.1|WP_102786369.1|2607580_2607961_+|Co2+/Mg2+-efflux-protein-ApaG
MDVSLPCIKIQVQTRYIEEQSNPEYQRFVFAYLITIKNLSAQTVQLMSRRWLITDADGKQTVVEGDGVVGEQPRIKANDEYTYSSGTALDTPVGVMQGQYLMIDEQGESFTVEIEPFRLAVPHVLN
>NZ_CP053744.1|WP_000035022.1|2607971_2608781_+|symmetrical-bis(5'-nucleosyl)-tetraphosphatase
MANYIVGDIQGCFDELQQLLKQAEFNSQLDTLWFAGDLVARGPKSLETLRFAYQLGDAARVVLGNHDLHLLSVALGHHSAKRRDQTQAILDAPDAAPLLDWLRQQPLLAEHQEFVLCHAGISPQWDLATARQAAQEVESVLRSPEWSTLIEQMYSDQPDAWHPTLQGIDRLRYIVNAFTRMRFCFPDGRLDMQCKLPPKEVTDGSLLPWFQLPQRIALEKTVIFGHWAALEGYVSETVIGLDTGCVWGGTLTMLRWEDKHYFSQAALPA
>NZ_CP053744.1|WP_102786367.1|2608930_2609428_-|type-3-dihydrofolate-reductase
MMISMIAAMADLRIIGKDNQMPWHLPADFAWFKRCTLGKPVVMGRKTYQSIGRPLPGRHNIVISRDASLQIEGVDVVTSIEAALAKAGEVEEVMIIGGGSLYAACLPMAHKLYITEIHAKLEGDTQFPEWGNDWLERSREHYPADEKNAYGMDFVIFERQYPLPT
>NZ_CP053744.1|WP_000954087.1|2609440_2609914_-|threonine/serine-exporter-family-protein
MLSWDLFFGLLNDMFFAAIPAVGFALVFNVPVPALKYCALGGALGHGSRYLMMHFGVPIEWASFFAATLVGMVGVYWSRRFLAHPKVFTVAALIPMVPGVFAFKAMIALVEINHVGFSPELMEALLENFLKAMFIIAGLAVGLAVPGLLFYRRKPII

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP053744_1	1.1\|2597829\|37\|NZ_CP053744\|PILER-CR	2597829-2597865	37	NC_049942	Escherichia phage JLK-2012, complete sequence	23524-23560	4	0.892
NZ_CP053744_1	1.1\|2597829\|37\|NZ_CP053744\|PILER-CR	2597829-2597865	37	NC_021742	Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence	35428-35464	4	0.892

1. spacer 1.1|2597829|37|NZ_CP053744|PILER-CR matches to NC_049942 (Escherichia phage JLK-2012, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
caggtcgccagttcgattccggtagccggcaccatat	Protospacer
.*********************.***********. *

2. spacer 1.1|2597829|37|NZ_CP053744|PILER-CR matches to NC_021742 (Serratia liquefaciens ATCC 27592 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.892

taggtcgccagttcgattccggcagccggcaccactt	CRISPR spacer
taggtcaccagttcgattccggtagccggcaccaatc	Protospacer
******.***************.*********** *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

670349 : 676966

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000210573.1\|670349_671483_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4
WP_000366561.1\|671494_672745_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.5e-99	49.5
WP_000543544.1\|672844_673294_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_175248741.1\|673319_674423_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.6e-44	33.3
WP_000493874.1\|674427_675081_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001122866.1\|675121_676231_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.9e-64	39.8
WP_000864130.1\|676495_676966_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7

DBSCAN-SWA_2

1536053 : 1563027

Vibrio_phage(80.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000948763.1\|1536053_1536365_+	hypothetical protein	E3U9J1	Vibrio_phage	6.6e-09	100.0
WP_060779833.1\|1536499_1536856_+	phage protein	G8IRV3	Vibrio_phage	7.2e-60	92.4
WP_175248902.1\|1536942_1537431_-	hypothetical protein	NA	NA	NA	NA
WP_064626869.1\|1537573_1538050_-	hypothetical protein	NA	NA	NA	NA
WP_156144343.1\|1538103_1538310_-	KTSC domain-containing protein	NA	NA	NA	NA
WP_058649093.1\|1538319_1538538_-	hypothetical protein	NA	NA	NA	NA
WP_032469415.1\|1539322_1539508_-	hypothetical protein	G8IRV2	Vibrio_phage	7.1e-19	86.9
WP_175248903.1\|1539516_1540884_-	toxin	Q64EV0	Vibrio_phage	2.4e-257	96.5
WP_001160095.1\|1540886_1541231_-	DUF2523 domain-containing protein	Q64EV1	Vibrio_phage	4.8e-61	100.0
WP_175248904.1\|1541230_1542628_-	hypothetical protein	Q64EV4	Vibrio_phage	2.3e-162	94.6
WP_000672170.1\|1542760_1542970_-	hypothetical protein	G8IRU8	Vibrio_phage	1.1e-20	81.2
WP_001900021.1\|1543003_1543234_-	hypothetical protein	G8IRU7	Vibrio_phage	3.9e-35	94.7
WP_001284206.1\|1543243_1543582_-	DUF1293 domain-containing protein	Q858R2	Vibrio_phage	1.3e-55	96.4
WP_175248905.1\|1543586_1544690_-	replication initiation factor domain-containing protein	Q8W6E3	Vibrio_phage	8.9e-218	98.4
WP_175248906.1\|1544679_1544883_-	hypothetical protein	E1CJD3	Vibrio_phage	7.7e-35	98.5
WP_114807524.1\|1544893_1545142_-	hypothetical protein	O56843	Vibrio_virus	6.4e-23	67.1
WP_000288489.1\|1545320_1545677_+	hypothetical protein	Q9MCC3	Vibrio_phage	3.7e-32	57.9
WP_175248907.1\|1546000_1559638_-	MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA	B3Y8K3	Vibrio_virus	8.4e-07	100.0
WP_071177929.1\|1559661_1560123_-	RTX toxin-activating lysine-acyltransferase RtxC	NA	NA	NA	NA
WP_032469422.1\|1560148_1560496_-	hypothetical protein	NA	NA	NA	NA
WP_175249268.1\|1560921_1563027_+	RTX toxin T1SS ABC transporter subunit RtxB	W8CYL7	Bacillus_phage	1.1e-38	26.9

DBSCAN-SWA_3

2299912 : 2307105

Anguillid_herpesvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001162850.1\|2299912_2300341_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4
WP_095488087.1\|2300544_2301834_-	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	7.6e-35	34.3
WP_000872174.1\|2302053_2302248_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_001124187.1\|2302296_2302635_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_001196554.1\|2302648_2304499_-	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	7.0e-106	41.1
WP_002043422.1\|2304522_2305038_-	co-chaperone HscB	NA	NA	NA	NA
WP_000301571.1\|2305086_2305410_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_000331703.1\|2305470_2305854_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_175249083.1\|2305890_2307105_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	3.9e-33	31.1

DBSCAN-SWA_4

2536965 : 2544204

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001279365.1\|2536965_2537853_+	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1
WP_175249123.1\|2538134_2540723_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.6e-34	23.3
WP_000116735.1\|2540816_2541824_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_114710273.1\|2541897_2542833_-	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_057550676.1\|2542832_2543459_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	51.5
WP_000698379.1\|2543451_2544204_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3

DBSCAN-SWA_5

2666417 : 2729913

Vibrio_phage(20.0%)

integrase,tRNA,protease,transposase

attL 2663782:2663797|attR 2683812:2683827

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2663782:2663797	attL	NA	NA	NA	NA
WP_175249152.1\|2666417_2668427_-\|integrase	integrase	NA	NA	NA	NA
WP_175249153.1\|2668419_2670003_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000687778.1\|2670008_2671181_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_000168287.1\|2671400_2671934_-	single-stranded DNA-binding protein	R9TR60	Vibrio_phage	3.8e-57	90.6
WP_001188315.1\|2672225_2672870_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001920788.1\|2673042_2673915_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	4.5e-63	47.2
WP_175249154.1\|2674070_2676893_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	56.9
WP_175249155.1\|2676957_2678742_+	oligosaccharyltransferase	NA	NA	NA	NA
WP_175248725.1\|2678787_2680176_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	1.7e-48	27.6
WP_175249156.1\|2680333_2681452_-	alanine--glyoxylate aminotransferase family protein	NA	NA	NA	NA
WP_000102982.1\|2681915_2683271_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_175249157.1\|2683344_2687025_-	methionine synthase	A0A140XBC7	Dickeya_phage	2.0e-24	83.6
2683812:2683827	attR	NA	NA	NA	NA
WP_000118232.1\|2687221_2688556_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	5.1e-42	39.8
WP_102786345.1\|2700486_2701245_-	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_175249158.1\|2701237_2702971_-	assimilatory sulfite reductase (NADPH) hemoprotein subunit	NA	NA	NA	NA
WP_175249159.1\|2702970_2704794_-	assimilatory sulfite reductase (NADPH) flavoprotein subunit	NA	NA	NA	NA
WP_000154955.1\|2704900_2705131_-	hypothetical protein	NA	NA	NA	NA
WP_001918194.1\|2705127_2705286_-	hypothetical protein	NA	NA	NA	NA
WP_175249160.1\|2705251_2705917_-	TIGR04219 family outer membrane beta-barrel protein	NA	NA	NA	NA
WP_000971085.1\|2706005_2706218_-	envelope stress response protein PspG	NA	NA	NA	NA
WP_001884460.1\|2706378_2707362_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_000245564.1\|2707719_2708184_+	zinc uptake transcriptional repressor Zur	NA	NA	NA	NA
WP_001200951.1\|2708193_2708655_+	chemotaxis protein CheX	NA	NA	NA	NA
WP_000004742.1\|2708771_2709950_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_000916640.1\|2710152_2711805_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_001913997.1\|2712592_2713678_-	alanine racemase	NA	NA	NA	NA
WP_000774910.1\|2713691_2715098_-	replicative DNA helicase	A0A1B0VG30	Salmonella_phage	5.3e-183	72.1
WP_175249161.1\|2715268_2716033_+	YdiY family protein	NA	NA	NA	NA
WP_001196054.1\|2716094_2716544_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_000090471.1\|2716577_2716805_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_000184784.1\|2716820_2717123_-	primosomal replication protein N	NA	NA	NA	NA
WP_001216668.1\|2717130_2717499_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_000675497.1\|2717710_2718187_-	bacterioferritin	NA	NA	NA	NA
WP_001884452.1\|2718256_2718445_-	bacterioferritin-associated ferredoxin	NA	NA	NA	NA
WP_000031644.1\|2718748_2719933_-	elongation factor Tu	M4M9V7	Vibrio_phage	5.8e-05	60.5
WP_000101804.1\|2720055_2722152_-	elongation factor G	A0A1S5SF82	Streptococcus_phage	1.3e-55	26.1
WP_001138050.1\|2722227_2722698_-	30S ribosomal protein S7	NA	NA	NA	NA
WP_000201237.1\|2722813_2723188_-	30S ribosomal protein S12	NA	NA	NA	NA
WP_000902450.1\|2723372_2723648_-	sulfurtransferase complex subunit TusB	NA	NA	NA	NA
WP_001044894.1\|2723657_2724014_-	sulfurtransferase complex subunit TusC	NA	NA	NA	NA
WP_000803700.1\|2724010_2724406_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	1.9e-16	40.7
WP_000140991.1\|2724402_2725119_-	transcriptional regulator	NA	NA	NA	NA
WP_175249162.1\|2725323_2726103_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_175249290.1\|2726287_2727223_+	hypothetical protein	NA	NA	NA	NA
WP_001890311.1\|2727234_2727453_+	SlyX family protein	NA	NA	NA	NA
WP_000084201.1\|2727493_2727682_-	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_001228766.1\|2727742_2728723_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_000312460.1\|2728725_2729913_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

DBSCAN-SWA_6

2867548 : 2874224

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_154025630.1\|2867548_2868838_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-14	28.6
WP_154025631.1\|2868827_2869640_-	ABC transporter permease	NA	NA	NA	NA
WP_154025632.1\|2869636_2870194_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.6e-53	59.8
WP_175249201.1\|2870193_2871084_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.5e-37	34.9
WP_069212354.1\|2871080_2871959_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.4e-110	67.2
WP_175249202.1\|2871982_2873047_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.7e-99	51.9
WP_000587803.1\|2873285_2874224_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	2.1e-34	35.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_CP053745

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

177361 : 289534

100

Vibrio_phage(69.39%)

integrase,transposase,protease,plate,tail,capsid,head,terminase,portal

attL 197227:197244|attR 225428:225445

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175249337.1\|177361_178576_-\|transposase	transposase	NA	NA	NA	NA
WP_175249338.1\|178675_180094_-	tryptophanase	NA	NA	NA	NA
WP_071908331.1\|180565_180637_-	tryptophanase leader peptide	NA	NA	NA	NA
WP_000462094.1\|180874_181087_+	DUF3820 family protein	NA	NA	NA	NA
WP_001236184.1\|181156_181639_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_175249660.1\|182183_184181_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_000078819.1\|184426_184639_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	1.8e-18	62.9
WP_000181878.1\|184915_185632_-	SIMPL domain-containing protein	NA	NA	NA	NA
WP_175249339.1\|185792_187445_-	BatD family protein	NA	NA	NA	NA
WP_175249340.1\|187438_189274_-	VWA domain-containing protein	NA	NA	NA	NA
WP_001893128.1\|189275_190232_-	VWA domain-containing protein	NA	NA	NA	NA
WP_000665196.1\|190218_190707_-	DUF4381 domain-containing protein	NA	NA	NA	NA
WP_175249341.1\|190703_191636_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_175249342.1\|191639_192596_-	MoxR family ATPase	NA	NA	NA	NA
WP_175249343.1\|192897_194814_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.8e-25	35.6
WP_000997601.1\|194873_195074_+	chromosome segregation ATPase	NA	NA	NA	NA
WP_033927757.1\|195349_196003_-	DsbA family protein	NA	NA	NA	NA
WP_000986003.1\|196649_197858_+	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
197227:197244	attL	NA	NA	NA	NA
WP_114719933.1\|198108_199341_+	peptidase T	NA	NA	NA	NA
WP_000400695.1\|199511_200387_+	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_175249344.1\|200383_201976_-	nitric oxide reductase transcriptional regulator NorR	NA	NA	NA	NA
WP_084981331.1\|202167_203352_+	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_000106983.1\|203496_203706_-	cold-shock protein	Q9AZD3	Lactococcus_phage	5.7e-17	68.3
WP_000792010.1\|204064_204292_+	alternative ribosome-rescue factor A	NA	NA	NA	NA
WP_000765283.1\|204679_205057_+	hypothetical protein	NA	NA	NA	NA
WP_000407070.1\|205330_205570_+	hypothetical protein	NA	NA	NA	NA
WP_000009679.1\|205656_206661_+	response regulator	NA	NA	NA	NA
WP_000880547.1\|206660_207107_+	PAS domain-containing protein	NA	NA	NA	NA
WP_175249345.1\|207156_208629_+	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_000935709.1\|208617_209613_-	2-hydroxyacid dehydrogenase	M1HUW8	Acanthocystis_turfacea_Chlorella_virus	2.1e-69	42.4
WP_170826474.1\|209855_211139_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_000779165.1\|211140_211983_-	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	7.5e-07	44.0
WP_000251270.1\|212048_212597_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_001217709.1\|213241_214285_+	GMP reductase	A0A0N9Q9A5	Chrysochromulina_ericina_virus	1.8e-98	53.6
WP_175249346.1\|214886_215636_+	hypothetical protein	NA	NA	NA	NA
WP_175249661.1\|215992_217024_-\|integrase	tyrosine-type recombinase/integrase	A0A1S6L016	Salmonella_phage	7.3e-97	54.1
WP_175249347.1\|217203_218316_+	ATP-binding protein	A0A2K9R7H3	Dishui_lake_phycodnavirus	1.2e-20	26.9
WP_175249348.1\|218312_220493_+	S8 family peptidase	NA	NA	NA	NA
WP_175249349.1\|220919_222212_-	hypothetical protein	NA	NA	NA	NA
WP_175249350.1\|222457_223102_-	helix-turn-helix domain-containing protein	A0A166YHA0	Vibrio_phage	5.3e-69	60.7
WP_061051021.1\|223250_223463_+	hypothetical protein	U3PFJ1	Vibrio_phage	1.4e-23	80.0
WP_175249351.1\|223573_224113_+	phage regulatory CII family protein	U3PIJ8	Vibrio_phage	2.7e-95	99.4
WP_175249352.1\|224125_224560_+	hypothetical protein	U3PDF0	Vibrio_phage	1.2e-72	97.9
WP_158128809.1\|224641_225160_+	hypothetical protein	U3PB56	Vibrio_phage	3.7e-57	75.9
WP_001198812.1\|225159_225387_+	hypothetical protein	U3PIK2	Vibrio_phage	2.6e-23	61.3
WP_061051025.1\|225585_225873_-	hypothetical protein	NA	NA	NA	NA
225428:225445	attR	NA	NA	NA	NA
WP_175249353.1\|225911_228497_+	replication endonuclease	A0A166YHE2	Vibrio_phage	0.0e+00	98.5
WP_172877807.1\|228696_228915_+	hypothetical protein	Q8HA55	Vibrio_phage	2.8e-30	98.6
WP_175249354.1\|228909_229161_-	ogr/Delta-like zinc finger family protein	Q8HA63	Vibrio_phage	3.6e-42	97.6
WP_175249355.1\|229277_229781_-	type II toxin-antitoxin system YafO family toxin	NA	NA	NA	NA
WP_175249356.1\|230360_231035_+	Bro-N domain-containing protein	Q8HA44	Vibrio_phage	1.1e-112	88.9
WP_175249357.1\|231031_232054_-\|portal	phage portal protein	U3PFK6	Vibrio_phage	6.8e-188	93.2
WP_172527527.1\|232050_233871_-\|terminase	terminase ATPase subunit family protein	U3PIL1	Vibrio_phage	0.0e+00	97.5
WP_175249358.1\|234044_234935_+\|capsid	GPO family capsid scaffolding protein	R9TRS3	Vibrio_phage	5.0e-86	67.5
WP_175249359.1\|234934_235936_+\|capsid	phage major capsid protein, P2 family	R9TPZ5	Vibrio_phage	2.0e-107	61.9
WP_175249360.1\|235946_236378_+	hypothetical protein	U3PCG2	Vibrio_phage	1.5e-48	53.5
WP_000494022.1\|236484_236946_+\|head	head completion/stabilization protein	U3PFL1	Vibrio_phage	5.8e-78	99.3
WP_000122190.1\|236942_237431_+\|tail	phage tail protein	U3PIL4	Vibrio_phage	2.7e-86	95.7
WP_175249361.1\|237417_238077_+	phage virion morphogenesis protein	U3PDG7	Vibrio_phage	2.9e-115	98.6
WP_114793011.1\|238078_239188_+	DUF2586 family protein	U3PB71	Vibrio_phage	4.5e-209	99.7
WP_000063626.1\|239187_239646_+	DUF2597 family protein	U3PCG7	Vibrio_phage	1.1e-81	98.0
WP_000382491.1\|239660_239870_+	TraR/DksA family transcriptional regulator	U3PFL5	Vibrio_phage	2.0e-33	100.0
WP_001077689.1\|239866_240094_+	hypothetical protein	U3PIL8	Vibrio_phage	2.1e-36	100.0
WP_175249362.1\|240080_240668_+	lysozyme	U3PDH1	Vibrio_phage	2.8e-109	99.0
WP_175249363.1\|240642_240984_+	hypothetical protein	U3PB75	Vibrio_phage	1.6e-48	94.7
WP_001892969.1\|241033_241195_+	hypothetical protein	A0A166YHN7	Vibrio_phage	3.7e-24	98.1
WP_000165786.1\|241191_241473_+	hypothetical protein	A9ZT39	Vibrio_virus	5.1e-45	100.0
WP_175249364.1\|241669_243487_+\|tail	phage tail tape measure protein	U3PFL8	Vibrio_phage	5.0e-266	81.3
WP_001113003.1\|243476_243809_+	DUF2590 family protein	U3PIM1	Vibrio_phage	1.7e-55	100.0
WP_175249365.1\|243805_245005_+\|plate	baseplate J/gp47 family protein	U3PDH5	Vibrio_phage	1.6e-220	98.7
WP_175249366.1\|245001_245661_+\|tail	phage tail protein	U3PB79	Vibrio_phage	2.2e-123	98.2
WP_175249367.1\|245657_247061_+\|tail	phage tail protein	Q8HA60	Vibrio_phage	1.9e-164	54.4
WP_175249368.1\|247060_247585_+\|tail	phage tail protein	Q8HA51	Vibrio_phage	1.2e-87	92.0
WP_175249369.1\|247587_248481_+	hypothetical protein	U3PIM3	Vibrio_phage	6.2e-153	94.9
WP_000457681.1\|248468_248942_+	hypothetical protein	U3PDI0	Vibrio_phage	6.6e-77	100.0
WP_175249370.1\|248938_250570_+	hypothetical protein	A0A160DHT6	Vibrio_phage	4.6e-303	95.8
WP_000019966.1\|251863_252136_-	Ni(II)/Co(II)-binding transcriptional repressor RcnR	NA	NA	NA	NA
WP_000118579.1\|253571_254594_+	DUF4118 domain-containing protein	W8CYF6	Bacillus_phage	7.4e-09	22.9
WP_175249371.1\|254596_255295_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.6e-25	32.6
WP_175249372.1\|256747_257401_+	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_175249373.1\|259224_259893_-	epimerase	NA	NA	NA	NA
WP_175249374.1\|260051_260612_-	phosphohydrolase	NA	NA	NA	NA
WP_175249375.1\|260765_261671_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_175249376.1\|261865_262732_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_102787165.1\|263586_264981_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-48	36.4
WP_000967523.1\|265170_266499_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000400328.1\|266749_267580_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.4e-58	47.4
WP_000717539.1\|267682_268210_+	nicotinate-nicotinamide nucleotide adenylyltransferase	NA	NA	NA	NA
WP_000362854.1\|268405_269947_+	DUF3369 domain-containing protein	NA	NA	NA	NA
WP_175249377.1\|270004_271951_-	ATP-binding protein	W8CYF6	Bacillus_phage	7.3e-05	24.4
WP_032477646.1\|272200_273175_+	hypothetical protein	NA	NA	NA	NA
WP_001046717.1\|273252_274833_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_001276502.1\|275236_276442_-	multidrug efflux MFS transporter EmrD	NA	NA	NA	NA
WP_000949610.1\|276694_276961_+	hypothetical protein	NA	NA	NA	NA
WP_000746869.1\|278150_279407_-	thermolabile hemolysin	NA	NA	NA	NA
WP_175249378.1\|280378_282604_+	cytolysin VCC	NA	NA	NA	NA
WP_000586206.1\|282904_284551_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.3e-22	29.4
WP_175249379.1\|284898_285837_+	triacylglycerol lipase	NA	NA	NA	NA
WP_175249380.1\|285846_286701_+	lipase secretion chaperone	NA	NA	NA	NA
WP_175249381.1\|286777_289534_-\|protease	M6 family metalloprotease PrtV	NA	NA	NA	NA

DBSCAN-SWA_2

499950 : 509201

Vibrio_phage(90.91%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043990497.1\|499950_500307_+	phage protein	G8IRV3	Vibrio_phage	1.4e-60	93.2
WP_057562864.1\|500373_501072_-	hypothetical protein	NA	NA	NA	NA
WP_057562865.1\|501197_502118_-	hypothetical protein	NA	NA	NA	NA
WP_057562866.1\|503099_504467_-	toxin	Q64EV0	Vibrio_phage	4.9e-258	98.5
WP_001160095.1\|504469_504814_-	DUF2523 domain-containing protein	Q64EV1	Vibrio_phage	4.8e-61	100.0
WP_148553389.1\|504813_506151_-	hypothetical protein	G8IRU9	Vibrio_phage	1.5e-49	60.2
WP_000672170.1\|506283_506493_-	hypothetical protein	G8IRU8	Vibrio_phage	1.1e-20	81.2
WP_175249458.1\|506526_506757_-	hypothetical protein	G8IRU7	Vibrio_phage	1.1e-34	93.4
WP_001284206.1\|506766_507105_-	DUF1293 domain-containing protein	Q858R2	Vibrio_phage	1.3e-55	96.4
WP_001112192.1\|507109_508213_-	replication initiation factor domain-containing protein	Q64EV8	Vibrio_phage	1.5e-220	100.0
WP_000502184.1\|508202_508406_-	hypothetical protein	C3W4P3	Vibrio_phage	2.7e-35	100.0
WP_057562869.1\|508416_508665_-	hypothetical protein	O56843	Vibrio_virus	8.3e-23	67.1
WP_175249459.1\|508832_509201_+	hypothetical protein	G8IRV4	Vibrio_phage	8.2e-51	84.7

DBSCAN-SWA_3

861077 : 880592

Vibrio_phage(37.5%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_113622214.1\|861077_861290_+	cold-shock protein	A0A1W6JNX5	Morganella_phage	2.4e-15	58.6
WP_175249558.1\|861596_863813_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.7e-62	33.5
WP_175249559.1\|863945_865421_-	ATPase	M4MHC7	Vibrio_phage	8.2e-41	34.5
WP_057573322.1\|865420_865681_-	hypothetical protein	NA	NA	NA	NA
WP_000115809.1\|865683_866061_-	hypothetical protein	A0A1I9KFD7	Aeromonas_phage	1.4e-18	45.0
WP_175249560.1\|866064_866715_-	hypothetical protein	A0A1I9KFE8	Aeromonas_phage	7.5e-39	44.2
WP_071187003.1\|866714_867056_-	hypothetical protein	NA	NA	NA	NA
WP_175249561.1\|867096_867459_-	hypothetical protein	NA	NA	NA	NA
WP_175249562.1\|867463_869440_-	DUF1983 domain-containing protein	A0A2L1IV54	Escherichia_phage	3.9e-54	33.7
WP_175249563.1\|869439_871047_-	hypothetical protein	A0A1I9KFD2	Aeromonas_phage	2.3e-129	45.6
WP_175249673.1\|871118_873623_-	right-handed parallel beta-helix repeat-containing protein	A0A240EWW2	Vibrio_phage	2.3e-19	31.2
WP_175249564.1\|873637_874267_-	hypothetical protein	A0A1I9KFD0	Aeromonas_phage	1.1e-23	33.3
WP_175249565.1\|874266_874866_-	hypothetical protein	NA	NA	NA	NA
WP_032474119.1\|874868_875333_-	hypothetical protein	A0A1I9KFH0	Aeromonas_phage	2.1e-27	55.7
WP_061050733.1\|875390_875771_-	hypothetical protein	M4MCI2	Vibrio_phage	1.8e-08	31.1
WP_000207893.1\|875785_876991_-	DUF4043 family protein	A0A088CC32	Shigella_phage	2.7e-135	58.3
WP_175249566.1\|877053_878058_-	ATPase	A0A1I9KFD1	Aeromonas_phage	1.2e-22	32.3
WP_069217411.1\|878175_878436_-	hypothetical protein	NA	NA	NA	NA
WP_000228309.1\|878447_879026_-	hypothetical protein	A0A1V0E8A2	Vibrio_phage	7.9e-24	36.9
WP_000835319.1\|879028_879250_-	hypothetical protein	NA	NA	NA	NA
WP_001007095.1\|879344_879521_-	hypothetical protein	NA	NA	NA	NA
WP_175242382.1\|879525_879684_-	hypothetical protein	NA	NA	NA	NA
WP_000460725.1\|879693_880212_-	hypothetical protein	Q6VT55	Vibrio_phage	1.0e-59	62.6
WP_001128531.1\|880280_880592_-\|holin	phage holin family protein	R9TR41	Vibrio_phage	2.2e-20	47.4

DBSCAN-SWA_4

890751 : 900862

Vibrio_phage(57.14%)

terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_113622070.1\|890751_892839_-\|portal	portal protein	A0A088CE71	Shigella_phage	1.5e-202	58.2
WP_175249568.1\|892835_894533_-\|terminase	terminase	B0FEF1	Escherichia_phage	8.9e-217	65.6
WP_175249569.1\|894525_895371_-	hypothetical protein	A0A2R2Z334	Escherichia_phage	3.2e-13	25.7
WP_175249570.1\|895484_896303_-	hypothetical protein	NA	NA	NA	NA
WP_088132550.1\|896366_897335_-	helix-turn-helix domain-containing protein	R9TPU9	Vibrio_phage	9.9e-96	58.7
WP_175249571.1\|897965_898202_-	helix-turn-helix transcriptional regulator	A0A1V0E8C7	Vibrio_phage	9.6e-21	70.1
WP_000781499.1\|898320_898986_+	helix-turn-helix domain-containing protein	A0A1V0E8B5	Vibrio_phage	3.8e-70	60.1
WP_175249572.1\|899205_899469_+	hypothetical protein	NA	NA	NA	NA
WP_000083581.1\|899474_899663_+	hypothetical protein	NA	NA	NA	NA
WP_001899819.1\|899638_900862_+	DUF3596 domain-containing protein	R9TMP3	Vibrio_phage	2.7e-183	76.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP053744

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NZ_CP053745

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection