CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LN854556	Staphylococcus aureus strain B155 chromosome 1	5 crisprs	cas3,DEDDh,DinG,csa3,WYL	2	1	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LN854556_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN854556_1

748671-748752

Unclear

Consensus_repeat	Method
TGAAATTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN854556_1

>merge|NZ_LN854556|1|748671-748752|CRISPRCasFinder
TGAAATTCTACAGACAATGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAATGAAATTCTACAGACAATGCAAGTTGG

>NZ_LN854556|1|1|748671-748752|CRISPRCasFinder
TGAAATTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACACAGAGAATTTCGAAA
TGAAATTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN854556.1\|WP_001245577.1\|750062_751019_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	unknown	unknown	gnl\|CDD\|226964
NZ_LN854556.1\|WP_054189251.1\|737334_738393_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_LN854556.1\|WP_054189254.1\|742688_743189_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_LN854556.1\|WP_054189261.1\|755204_756083_+\|EMYY-motif-lipoprotein	unknown	unknown	gnl\|CDD\|380197
NZ_LN854556.1\|WP_054189259.1\|753516_754440_-\|UDP-N-acetylmuramate-dehydrogenase	unknown	unknown	gnl\|CDD\|184386
NZ_LN854556.1\|WP_000985617.1\|756236_756557_+\|bacillithiol-system-redox-active-protein-YtxJ	unknown	unknown	gnl\|CDD\|378538
NZ_LN854556.1\|WP_054189260.1\|754566_755085_-\|GrpB-family-protein	unknown	unknown	gnl\|CDD\|377252
NZ_LN854556.1\|WP_054189255.1\|743208_744075_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_LN854556.1\|WP_001127269.1\|753184_753499_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226801
NZ_LN854556.1\|WP_061745593.1\|740842_742348_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_LN854556.1\|WP_054189252.1\|739643_740561_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513
NZ_LN854556.1\|WP_000562498.1\|747459_748431_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_LN854556.1\|WP_000692521.1\|744875_745274_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_LN854556.1\|WP_000876318.1\|749104_750076_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_LN854556.1\|WP_000197261.1\|738550_739093_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_LN854556.1\|WP_000866741.1\|756981_758106_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|224840
NZ_LN854556.1\|WP_054189250.1\|735580_737095_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_LN854556.1\|WP_054189258.1\|751895_752924_+\|siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|226966
NZ_LN854556.1\|WP_054189257.1\|751015_751777_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226963
NZ_LN854556.1\|WP_054189256.1\|745236_747342_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069

Protein	Function_ID	Function_description	E-value
NZ_LN854556.1\|WP_001245577.1\|750062_751019_+\|iron-chelate-uptake-ABC-transporter-family-permease-subunit	gnl\|CDD\|226964	COG4605, CeuC, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	4.81847e-122
NZ_LN854556.1\|WP_054189251.1\|737334_738393_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_LN854556.1\|WP_054189254.1\|742688_743189_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	2.56186e-78
NZ_LN854556.1\|WP_054189261.1\|755204_756083_+\|EMYY-motif-lipoprotein	gnl\|CDD\|380197	NF033194, lipo_EMYY, EMYY motif lipoprotein. Members of this family are lipoproteins, about 300 amino acids long in precursor form, found broadly in the genus Staphylococcus and in some related species.	5.4899e-106
NZ_LN854556.1\|WP_054189259.1\|753516_754440_-\|UDP-N-acetylmuramate-dehydrogenase	gnl\|CDD\|184386	PRK13906, murB, UDP-N-acetylmuramate dehydrogenase.	0
NZ_LN854556.1\|WP_000985617.1\|756236_756557_+\|bacillithiol-system-redox-active-protein-YtxJ	gnl\|CDD\|378538	pfam11009, DUF2847, Protein of unknown function (DUF2847). Some members in this bacterial family of proteins with unknown function are annotated as YtxJ, a putative general stress protein. This cannot be confirmed.	1.13449e-42
NZ_LN854556.1\|WP_054189260.1\|754566_755085_-\|GrpB-family-protein	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	2.06037e-26
NZ_LN854556.1\|WP_054189255.1\|743208_744075_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	6.91191e-10
NZ_LN854556.1\|WP_001127269.1\|753184_753499_-\|hypothetical-protein	gnl\|CDD\|226801	COG4357, COG4357, Zinc finger domain containing protein (CHY type) [Function unknown].	1.41435e-51
NZ_LN854556.1\|WP_061745593.1\|740842_742348_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	3.44064e-172
NZ_LN854556.1\|WP_054189252.1\|739643_740561_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	4.24579e-79
NZ_LN854556.1\|WP_000562498.1\|747459_748431_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_LN854556.1\|WP_000692521.1\|744875_745274_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_LN854556.1\|WP_000876318.1\|749104_750076_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NZ_LN854556.1\|WP_000197261.1\|738550_739093_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	6.4494e-108
NZ_LN854556.1\|WP_000866741.1\|756981_758106_+\|glycerate-kinase	gnl\|CDD\|224840	COG1929, COG1929, Glycerate kinase [Carbohydrate transport and metabolism].	1.26111e-160
NZ_LN854556.1\|WP_054189250.1\|735580_737095_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.62554e-152
NZ_LN854556.1\|WP_054189258.1\|751895_752924_+\|siderophore-ABC-transporter-substrate-binding-protein	gnl\|CDD\|226966	COG4607, CeuA, ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism].	3.33698e-127
NZ_LN854556.1\|WP_054189257.1\|751015_751777_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226963	COG4604, CeuD, ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism].	1.09608e-149
NZ_LN854556.1\|WP_054189256.1\|745236_747342_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0

>NZ_LN854556.1|WP_000562498.1|747459_748431_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NZ_LN854556.1|WP_054189256.1|745236_747342_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKGGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMGIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_LN854556.1|WP_000692521.1|744875_745274_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_LN854556.1|WP_054189255.1|743208_744075_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSALGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAFTYEPMSQTQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKVIKK
>NZ_LN854556.1|WP_054189254.1|742688_743189_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPHSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_LN854556.1|WP_061745593.1|740842_742348_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALTGLFTSMFFIIIGSGIMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_LN854556.1|WP_054189252.1|739643_740561_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKDYAKDVDILFILGGDGTVNELINGVMIHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDEKTYSGETSMLLTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_LN854556.1|WP_000197261.1|738550_739093_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNGWKDVEQYFLDNIEK
>NZ_LN854556.1|WP_054189251.1|737334_738393_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSIERERFYQLPQSEHFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_LN854556.1|WP_054189250.1|735580_737095_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETQNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKKSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_LN854556.1|WP_000876318.1|749104_750076_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ
>NZ_LN854556.1|WP_001245577.1|750062_751019_+|iron-chelate-uptake-ABC-transporter-family-permease-subunit
MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ
>NZ_LN854556.1|WP_054189257.1|751015_751777_+|ABC-transporter-ATP-binding-protein
MIQVGNLTKTINNQMILEDISIEIEKGKLTSLIGPNGAGKSTLLSAICRLIRFDNGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFPYSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLDEPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGRLVKSDLKDNVIQSSVLSDLYDMDIHIEHIRNQRICLYFKD
>NZ_LN854556.1|WP_054189258.1|751895_752924_+|siderophore-ABC-transporter-substrate-binding-protein
MKKTVLYLVLAVMFLLAACGNNSDKEQSKSETKGSKDTVKIENNYKMRGEKKDGSDAKKVKETVEVPKNPKNAVVLDYGALDVMKEMGLSDKVKALPKGEGGKSLPNFLESFKDEKYTNVGNLKEVNFDKIAATKPEVIFISGRTANQKNLDEFKKAAPKAKIVYVGADEKNLVGSMKQNTENIGKIYDKEVKAKELNKDLDNKIASMKDKTKNFNKTVMYLLVNEGELSTFGPKGRFGGLVYDTLGFNAVDKKVSNSNHGQNVSNEYVNKENPDVILAMDRGQAVSGKSTAKQALNNPVLKNVKAIKEDKVYNLDPKLWYFAAGSTTTTIKQIEELDKVVK
>NZ_LN854556.1|WP_001127269.1|753184_753499_-|hypothetical-protein
MPKVYGSLIDTETRCRHYFTEEDIIAIKFKCCNKYYPCYKCHNEFEKHAIKRWSEPSFNEKAILCGVCKHELTINEYMMVERCPNCQSRFNNRCKYHYHIYFEI
>NZ_LN854556.1|WP_054189259.1|753516_754440_-|UDP-N-acetylmuramate-dehydrogenase
MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTAKELELDYRNSIIQKEHLVVLEAAFTLAPGKLTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIKLNREVRIIGEHPKES
>NZ_LN854556.1|WP_054189260.1|754566_755085_-|GrpB-family-protein
MYSNVQPFINSDLTNCFQSQYTEIESLLFNLLDSPVKYTKHIGGTHHFKYSTEPILDILVGVENLHDITSLDEKRLNYVGFYRLHHKYNKKVMMAKFNNFHELKQQVRLHIIQMNTQTFESYLALDRLLSTNDEIALQFNTKKHQILQHSLTIRQYEMQKQQYFEKLCKKYL
>NZ_LN854556.1|WP_054189261.1|755204_756083_+|EMYY-motif-lipoprotein
MKKIVIIAVLAILFVVISACGNKEKEAQHQFTKQFKDVEQKQKELQHVMDNIHLKEIDHLSKTDTTDKNSKEFKALQEDVKNHLIPKFEAYYKSAKNLPDDTMRVKKLKKEYMTLANEKKDVIYQLKKFIGLCNQSIKYNEDILDYTKQFEKNRYKVESEIKLADNKSEATNLTTKLEHNNKALRDTAKKNLDDSKENEIKGAIKNHIMPMIEKQITDINQTNISDKHVNNARKNAIEMYYSLQNYYNTRIETIKVSEKLSKVDVDKLPKKGIDITHGDKAFEKKLEKLEEK
>NZ_LN854556.1|WP_000985617.1|756236_756557_+|bacillithiol-system-redox-active-protein-YtxJ
MAIKLSSIDQFEQVIEENKYVFVLKHSETCPISANAYDQFNKFLYERDMDGYYLIVQQERDLSDYIAKKTNVKHESPQAFYFVNGEMVWNRDHGDINVSSLAQAEE
>NZ_LN854556.1|WP_000866741.1|756981_758106_+|glycerate-kinase
MKVLVAMDEFHGIISSYQANRYVEEAVASQIETADVVQVPLFNGRHELLDSVFLWQSGQKYRIPVHDADMNEVEGVYGQTDTGMTVIEGNLFLKGKKPIVERTSYGLGEMIKHALDNDAKHVVISLGGIDSFDAGAGMLQALGAQFYDDEGRVVDMRQGAGVIKYIRRMDMSNLHPKMETARIQVMSDFSSRLYGKQSEIMQTYDAHQLNHNQAAEIDNLIWYFSELFKSELKIAIGPVERGGAGGGIAAVLNGLYQAEILTSHALVDQLTHLENLVEQADLIIFGEGLNENDQLLETTTLRIAELCHKHQKVAIAICATAEKFDLFESQGVTAMFNTFIDMPESYTDFKMGLQIRHYTVQSLKLLKTHFNVEV

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Crispr_ID: NZ_LN854556_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN854556_2

968034-968124

Orphan

Consensus_repeat	Method
ATAATGTGCAAGTTGGGGTGTGGGCCCCAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN854556_2

>merge|NZ_LN854556|2|968034-968124|CRISPRCasFinder
ATAATGTGCAAGTTGGGGTGTGGGCCCCAACACAGAAGCTGGCGGAAAGTCAGCATAAAATAATGTGCAAGTTGGGGTGTGGGCCCCAACA

>NZ_LN854556|2|2|968034-968124|CRISPRCasFinder
ATAATGTGCAAGTTGGGGTGTGGGCCCCAACA	CAGAAGCTGGCGGAAAGTCAGCATAAA
ATAATGTGCAAGTTGGGGTGTGGGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN854556.1\|WP_054190345.1\|963974_964259_+\|lactococcin-972-family-bacteriocin	unknown	unknown	gnl\|CDD\|370615
NZ_LN854556.1\|WP_054190335.1\|975537_976341_+\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	unknown	unknown	gnl\|CDD\|274729
NZ_LN854556.1\|WP_054190336.1\|973877_975551_+\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	unknown	unknown	gnl\|CDD\|224087
NZ_LN854556.1\|WP_000766009.1\|968383_968740_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NZ_LN854556.1\|WP_054190344.1\|964302_966267_+\|bacteriocin-associated-integral-membrane-family-protein	unknown	unknown	gnl\|CDD\|226999
NZ_LN854556.1\|WP_099119695.1\|963259_963337_+\|putative-holin-like-toxin	unknown	unknown	unknown
NZ_LN854556.1\|WP_000070966.1\|971409_972348_-\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	unknown	unknown	gnl\|CDD\|235695
NZ_LN854556.1\|WP_000867357.1\|970427_970643_-\|TM2-domain-containing-protein	unknown	unknown	gnl\|CDD\|225196
NZ_LN854556.1\|WP_077446589.1\|967315_967606_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_054190346.1\|960981_961968_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|161920
NZ_LN854556.1\|WP_000184946.1\|976333_977155_+\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	unknown	unknown	gnl\|CDD\|180958
NZ_LN854556.1\|WP_054190338.1\|970807_971359_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LN854556.1\|WP_054190337.1\|972529_973891_+\|isochorismate-synthase-MenF	unknown	unknown	gnl\|CDD\|224091
NZ_LN854556.1\|WP_001033867.1\|962357_962960_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	unknown
NZ_LN854556.1\|WP_077446593.1\|970232_970364_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_077446590.1\|967746_967884_+\|poly(glycerol-phosphate)-alpha-glucosyltransferase	unknown	unknown	gnl\|CDD\|340831
NZ_LN854556.1\|WP_000214898.1\|962166_962343_+\|YkvS-family-protein	unknown	unknown	gnl\|CDD\|227210
NZ_LN854556.1\|WP_054190340.1\|969227_970187_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|226959
NZ_LN854556.1\|WP_054190342.1\|966586_967228_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|188353
NZ_LN854556.1\|WP_054190343.1\|966269_966590_+\|YxeA-family-protein	unknown	unknown	gnl\|CDD\|227613

Protein	Function_ID	Function_description	E-value
NZ_LN854556.1\|WP_054190345.1\|963974_964259_+\|lactococcin-972-family-bacteriocin	gnl\|CDD\|370615	pfam09683, Lactococcin_972, Bacteriocin (Lactococcin_972). These sequences represent bacteriocins related to lactococcin. Members tend to be found in association with a seven transmembrane putative immunity protein.	4.61027e-09
NZ_LN854556.1\|WP_054190335.1\|975537_976341_+\|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase	gnl\|CDD\|274729	TIGR03695, menH_SHCHC, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase. This protein catalyzes the formation of SHCHC, or (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, by elmination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Note that SHCHC synthase activity previously was attributed to MenD, which in fact is SEPHCHC synthase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	2.98551e-120
NZ_LN854556.1\|WP_054190336.1\|973877_975551_+\|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase	gnl\|CDD\|224087	COG1165, MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [Coenzyme metabolism].	0
NZ_LN854556.1\|WP_000766009.1\|968383_968740_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	3.02436e-17
NZ_LN854556.1\|WP_054190344.1\|964302_966267_+\|bacteriocin-associated-integral-membrane-family-protein	gnl\|CDD\|226999	COG4652, COG4652, Uncharacterized protein conserved in bacteria [Function unknown].	0
NZ_LN854556.1\|WP_000070966.1\|971409_972348_-\|1,4-dihydroxy-2-naphthoate-polyprenyltransferase	gnl\|CDD\|235695	PRK06080, PRK06080, 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated.	3.61649e-125
NZ_LN854556.1\|WP_000867357.1\|970427_970643_-\|TM2-domain-containing-protein	gnl\|CDD\|225196	COG2314, XynA, Predicted membrane protein [Function unknown].	1.26488e-08
NZ_LN854556.1\|WP_054190346.1\|960981_961968_-\|lipoate--protein-ligase	gnl\|CDD\|161920	TIGR00545, Probable_lipoate-protein_ligase_A, lipoyltransferase and lipoate-protein ligase. One member of this group of proteins is bovine lipoyltransferase, which transfers the lipoyl group from lipoyl-AMP to the specific Lys of lipoate-dependent enzymes. However, it does not first activate lipoic acid with ATP to create lipoyl-AMP and pyrophosphate. Another member of this group, lipoate-protein ligase A from E. coli, catalyzes both the activation and the transfer of lipoate. Homology between the two is full-length, except for the bovine mitochondrial targeting signal, but is strongest toward the N-terminus. [Protein fate, Protein modification and repair].	1.39722e-115
NZ_LN854556.1\|WP_000184946.1\|976333_977155_+\|1,4-dihydroxy-2-naphthoyl-CoA-synthase	gnl\|CDD\|180958	PRK07396, PRK07396, dihydroxynaphthoic acid synthetase; Validated.	0
NZ_LN854556.1\|WP_054190338.1\|970807_971359_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.15599e-08
NZ_LN854556.1\|WP_054190337.1\|972529_973891_+\|isochorismate-synthase-MenF	gnl\|CDD\|224091	COG1169, MenF, Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.00865e-162
NZ_LN854556.1\|WP_077446590.1\|967746_967884_+\|poly(glycerol-phosphate)-alpha-glucosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	9.89998e-07
NZ_LN854556.1\|WP_000214898.1\|962166_962343_+\|YkvS-family-protein	gnl\|CDD\|227210	COG4873, COG4873, Uncharacterized protein conserved in bacteria [Function unknown].	1.25817e-27
NZ_LN854556.1\|WP_054190340.1\|969227_970187_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|226959	COG4594, FecB, ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism].	8.57664e-150
NZ_LN854556.1\|WP_054190342.1\|966586_967228_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|188353	TIGR03608, L_ocin_972_ABC, putative bacteriocin export ABC transporter, lactococcin 972 group. A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	2.24705e-99
NZ_LN854556.1\|WP_054190343.1\|966269_966590_+\|YxeA-family-protein	gnl\|CDD\|227613	COG5294, COG5294, Uncharacterized protein conserved in bacteria [Function unknown].	2.34478e-38

>NZ_LN854556.1|WP_077446590.1|967746_967884_+|poly(glycerol-phosphate)-alpha-glucosyltransferase
MADKILKLVNNDVLAEVFGSKARKNIIEKYSTESILEKWLNLFNS
>NZ_LN854556.1|WP_077446589.1|967315_967606_-|hypothetical-protein
MYWTCHFKNKIGGVILTRTYNIIGILSCLLSFIIMVLPMIWNAASALWFFPGAIIILLLSLVIVFCYIKTKNQLHLLLIVLNIIILLFFSLPLLLS
>NZ_LN854556.1|WP_054190342.1|966586_967228_+|ABC-transporter-ATP-binding-protein
MIELKDLTIQKGKTHILKKLNLKFQCGKSYALIGKSGCGKSTLLNTIAGLEKTGKQYVYFNGQLEQFKSNFYRDKLGYLFQNYGLIDNLTVNENLDIGLAYKKISKKEKEQLKIRYIEQFGLSNSLKRKVHTLSGGEQQRVALIRMMLKDPIVMLADEPTGALDPKTGQMIIQSLFDLVNENKVLILATHDMAIANQCDEIIDLEQYRKVASM
>NZ_LN854556.1|WP_054190343.1|966269_966590_+|YxeA-family-protein
MKFIIAILLGLIVSITIAFTIIHHPILDRFNPFLKTEYSYAKVPKGTQQYVNITAYSERGEKLGYKLTFNGFSPSRTYVEIKHKGQYVISITYVEKEDTPKEVRQE
>NZ_LN854556.1|WP_054190344.1|964302_966267_+|bacteriocin-associated-integral-membrane-family-protein
MKWFKLILDVTIFILIAILLFVYTYKENEEILPDTKYPIAVTDWNKKYSKNEIYKRINQFARNENVAIYKSTSNYTNKNVDKDIYVFNKSKATTITPFNAKYNIHYLSDDELLKKDIKGSYFVKDKNFDVSKFINFLKEYGVNAESYKIDHMMIAVGVIKQMNIVVPLSSLLIVYFIYYIFEKNINFKAYAIKYLNGFTLRKIIFENFSKKCTYWVTLIITQILLTTSVLWILNYTGNLDLFILRLVLLSCLFILTISVINLWTFLMLLNLNIANMIKGKQHFKTIRFINTVCKSILLVLIASVMIENTSVIKDLNKIKETEKYWNVLDDYYTIEFAPYHETKQSLIDNMVRSEQLVKASEAENNAILFKPKGDSVDNDNFSPDEGNVILVNNQFWSIYHKQFQPDIPIENQKNNVEVIIPQKFHEVRNEINQAYHSWFEFVQNKNNKENKLSIQFINKNDYRIFTFDARDNRHLSFIEAPIIVNVQASDLSNDFYYAMISQGGYLFKNYDALVKNIEKYHLDGEISGITNYKDSVMEMYHENNLKLTVLNFSQIIIAIILIIIILFDVKYYFEQHRKLLVIKKLYGYSTLRANYQYLLINNIVVVFIGILTDVILHSRYIMMIFATIIVVQILLQICSLYYHGRRFNEVIKEF
>NZ_LN854556.1|WP_054190345.1|963974_964259_+|lactococcin-972-family-bacteriocin
MKNKIFGAILYLTLALGLSTAAYASTEYAEGGTWSHGVGSKYVWSYYYHGHKGHGATAIGKYRSFSGYTRAGVKAKASATKHNWWVNRAYYNIY
>NZ_LN854556.1|WP_099119695.1|963259_963337_+|putative-holin-like-toxin
MLSFGMFIVTFIGVVVAIINLNNKK
>NZ_LN854556.1|WP_001033867.1|962357_962960_+|CPBP-family-intramembrane-metalloprotease
MNKISKALTWFIISFIIFHLILFIMWGEHQEYWYLYTGIMLIAGISYVFYQRDIESKRLLTSIGVGIITAIILIMLQLLFSLITSNLSYSSLIKELARTGVNWKWQMLVTLLFVIPCHELYMRTVLQKELTHFSIPKWVAILITAICSSSLFIYLDNWWIVTFIFVAQVILSLSYEYTRRIATTSVAQIVAIILLLIFNA
>NZ_LN854556.1|WP_000214898.1|962166_962343_+|YkvS-family-protein
MTVAEVGNIVEFMDGLRGRVEKINDNSVIVDLTIMENFNDLDLPEKTVINHKRYKIVE
>NZ_LN854556.1|WP_054190346.1|960981_961968_-|lipoate--protein-ligase
MKFISNNNITDPTLNLAMEEYVLKNLPAEESYFLFYINRPSIIVGKNQNTIEEVNQTYIDAHNIDVVRRISGGGAVYHDTGNLNFSFITDDDGNSFHNFQKFTEPIVQALQSLGVNAELTGRNDIQVGQAKISGNAMVKVKNRMFSHGTLMLNSDLDEVQNALKVNPAKIKSKGIKSVRKRVANIQEFLNDPLEIEEFKKIILKTIFGETEVEEYKLTDEDWKNIEKLSNDKYRTWEWNYGRNPKYNFEREEKFEKGFVQIKFDVKRGKIEHAKIFGDFFGVGDVTDLENALVGCLHDFEHIEEALTEYDLYHYFGDIDKHELIRLMS
>NZ_LN854556.1|WP_000766009.1|968383_968740_-|DoxX-family-protein
MKLGMLLIRWMLATSFLVHGTLKFVDLDGTIHFLGSLGLPPTIAVLMSIGEVVGGLALIIGFLTPYVNVFYICVMLGSIFTLKLTRGYVSGYEFEIIHIVMNLACISSYSWKKWLQFY
>NZ_LN854556.1|WP_054190340.1|969227_970187_+|ABC-transporter-substrate-binding-protein
MNRNLFKLVMFILIFVVLAAGCGQKDTEDKQEMTTIKDELGTEKIKKNSKRVVVLEYSFADYLAALDMKPVGIADDGSTKNITKSVRDKIGAYESVGSRPQPNMEVISKLKPDLIIADVSRHKKIKSELSKIAPTIMLVSGTGDYNANIEAFKTVAKAVGKEKEGENRLEKHDKILAEIRKKIEQSTLKSAFAFGISREGMFINNEDTFMGQFLIKMGIQPEVTKDKTTHVGERKGGPYIYLNNEELANINPKVMILATDGKTDKNRTKFIDPAVWKSLKAVKDNKVYDVDRNKWLKSRGIIASESMAEDLEKIAEKAK
>NZ_LN854556.1|WP_077446593.1|970232_970364_-|hypothetical-protein
MRYVTMRQFIKRIVKTILVGYVIKFIRNKISGKSSHPTDNKHN
>NZ_LN854556.1|WP_000867357.1|970427_970643_-|TM2-domain-containing-protein
MKVNKAIYVIVALFLGGLGIHKFYADKFGQGLFHLLFFWTGIPTIISIIHAIFVIFTKKADKDGYIIFPKN
>NZ_LN854556.1|WP_054190338.1|970807_971359_+|GNAT-family-N-acetyltransferase
MIRQARPEDRFDIAKLVYMVWDDMELELVKHLPKDMVLDAIEKSCVDATYRTFYQHILVYEVENKVAGCIISYSGENELKYEKAWELLDLPEEIKQYGTPLPVKEAKDDEYYIETIATFASYRGRGIATKLLTSLLESNTHVKWSLNCDINNEAALNLYKKVGFISDGQIELYKHMYHHLIVK
>NZ_LN854556.1|WP_000070966.1|971409_972348_-|1,4-dihydroxy-2-naphthoate-polyprenyltransferase
MSNQYQQYSTVKKYWHLMRPHTLTASVVPVLVGTAASKIYFLGSEDHIKISLFIAMLLACLLIQAATNMFNEYYDYKKGLDDHESVGIGGAIVRNGMSPELVLRLAIAFYILAAILGLFLAANSSFWLLPVGLVCMAVGYLYTGGPFPISWTPFGELFSGVFMGMFIIVIAFFIQTGNIQSYVIWLSVPIVITIGLINMANNIRDRVKDKASGRKTLPILLGKNASLTFMAIMYFIAYAFIVLTIIIKPGGSLFYLLALLSFPMPVKVIRRFKKNDTPPTMMPAMAAAGKTNTFFGLLYALGIYISALFAGI
>NZ_LN854556.1|WP_054190337.1|972529_973891_+|isochorismate-synthase-MenF
MATGVIEDYIVKEIYDSSKEWVSVEVKLSQSLDPSTLFHLTDNEAGDRFYMRLNDNQTSYFGYKAIQLFKNNSKNKQSIFKDWEKLKHNITFIHPQSERHHLRLVGGFQFSSHKSDDEWREFGLNHFVLPEVLISTDINGTFLTYTVKQGNFNIDVLNGLVNFFNDATDIDVDEQIGEITRNEDIYKDDWRQLVVEAIESINNEEKIVLARRRLIKFDKDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLMKVNNQILSTKAVAGTIKRSQDEDEDTKNVEAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYHLYTEIKAPLKDDSYISLIDNLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYIDIYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGVDMNGKS
>NZ_LN854556.1|WP_054190336.1|973877_975551_+|2-succinyl-5-enolpyruvyl-6-hydroxy-3--cyclohexene-1-carboxylic-acid-synthase
MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETIDAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYELPILADPLSHLRKFDHPNVICTYDLLFRSGLDLKVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEETTVNRVSWLEKWQCLEIKGRKEIECYIEQATDESAFVGELIKKTSEKDALFISNSMPIRDIDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKQITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNAALLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
>NZ_LN854556.1|WP_054190335.1|975537_976341_+|2-succinyl-6-hydroxy-2,-4-cyclohexadiene-1-carboxylate-synthase
MTHYNYYEANVETNQVLVLLHGFLSDSRTYHNHIDKYTDICHVITIDLPGHGEDQSSMDETWNFDYITTLLDRILVKYKYKSITLFGYSMGGRVALYYAINGHIPISNLILESTSPGIKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQLELPVETQHQIRQQRLSQLPQKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGEYDEKFLQIAKKMANLIPNSKCKLISATGHTIHVEDSDEFDTMILGFLKEEQND
>NZ_LN854556.1|WP_000184946.1|976333_977155_+|1,4-dihydroxy-2-naphthoyl-CoA-synthase
MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDQVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP

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Crispr_ID: NZ_LN854556_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN854556_3

2000611-2000699

Orphan

Consensus_repeat	Method
CAATCCAATTTCTCTATGTTGGGGCCCCACC	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NZ_LN854556_3

>merge|NZ_LN854556|3|2000611-2000699|CRISPRCasFinder
CAATCCAATTTCTCTATGTTGGGGCCCCACCCCAACTTACATTGCTTGTAGAAATTGGCAATCCAATTTCTCTATGTTGGGGCCCCACC

>NZ_LN854556|3|3|2000611-2000699|CRISPRCasFinder
CAATCCAATTTCTCTATGTTGGGGCCCCACC	CCAACTTACATTGCTTGTAGAAATTGG
CAATCCAATTTCTCTATGTTGGGGCCCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN854556.1\|WP_000545370.1\|2001136_2002564_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NZ_LN854556.1\|WP_054189631.1\|1992954_1994268_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	unknown	unknown	gnl\|CDD\|223840
NZ_LN854556.1\|WP_054189625.1\|2010001_2012194_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_LN854556.1\|WP_054189632.1\|1992221_1992953_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_LN854556.1\|WP_054189626.1\|2007994_2009998_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137
NZ_LN854556.1\|WP_000949467.1\|1994559_1995060_+\|H-type-ferritin-FtnA	unknown	unknown	gnl\|CDD\|224445
NZ_LN854556.1\|WP_054189624.1\|2013464_2014760_-\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|176464
NZ_LN854556.1\|WP_054189628.1\|1999530_2000478_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
NZ_LN854556.1\|WP_054189629.1\|1998088_1999450_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_LN854556.1\|WP_054189627.1\|2004704_2006243_+\|sodium/proline-symporter-PutP	unknown	unknown	gnl\|CDD\|273981
NZ_LN854556.1\|WP_000272064.1\|2012190_2012883_-\|heptaprenylglyceryl-phosphate-synthase	unknown	unknown	gnl\|CDD\|224560
NZ_LN854556.1\|WP_048523903.1\|1996071_1997142_-\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|235035
NZ_LN854556.1\|WP_001165363.1\|2013054_2013357_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226893
NZ_LN854556.1\|WP_000027928.1\|2002576_2004034_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl\|CDD\|234572
NZ_LN854556.1\|WP_054189630.1\|1997388_1997919_-\|DUF3267-domain-containing-protein	unknown	unknown	gnl\|CDD\|378690
NZ_LN854556.1\|WP_001790679.1\|1995141_1995234_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_000170162.1\|2004035_2004338_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810
NZ_LN854556.1\|WP_000831695.1\|2006782_2007982_-\|CamS-family-sex-pheromone-protein	unknown	unknown	gnl\|CDD\|227188
NZ_LN854556.1\|WP_000613738.1\|1995450_1996005_+\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
NZ_LN854556.1\|WP_001790257.1\|1992023_1992134_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LN854556.1\|WP_000545370.1\|2001136_2002564_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_LN854556.1\|WP_054189631.1\|1992954_1994268_-\|lipid-II-isoglutaminyl-synthase-subunit-MurT	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	9.1179e-99
NZ_LN854556.1\|WP_054189625.1\|2010001_2012194_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LN854556.1\|WP_054189632.1\|1992221_1992953_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	3.80943e-120
NZ_LN854556.1\|WP_054189626.1\|2007994_2009998_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NZ_LN854556.1\|WP_000949467.1\|1994559_1995060_+\|H-type-ferritin-FtnA	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
NZ_LN854556.1\|WP_054189624.1\|2013464_2014760_-\|adenylosuccinate-lyase	gnl\|CDD\|176464	cd01360, Adenylsuccinate_lyase_1, Adenylsuccinate lyase (ASL)_subgroup 1. This subgroup contains bacterial and archeal proteins similar to ASL, a member of the Lyase class I family. Members of this family for the most part catalyze similar beta-elimination reactions in which a C-N or C-O bond is cleaved with the release of fumarate as one of the products. These proteins are active as tetramers. The four active sites of the homotetrameric enzyme are each formed by residues from three different subunits. ASL catalyzes two steps in the de novo purine biosynthesis: the conversion of 5-aminoimidazole-(N-succinylocarboxamide) ribotide (SAICAR) into 5-aminoimidazole-4-carboxamide ribotide (AICAR) and, the conversion of adenylsuccinate (SAMP) into adenosine monophosphate (AMP).	0
NZ_LN854556.1\|WP_054189628.1\|1999530_2000478_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
NZ_LN854556.1\|WP_054189629.1\|1998088_1999450_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
NZ_LN854556.1\|WP_054189627.1\|2004704_2006243_+\|sodium/proline-symporter-PutP	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NZ_LN854556.1\|WP_000272064.1\|2012190_2012883_-\|heptaprenylglyceryl-phosphate-synthase	gnl\|CDD\|224560	COG1646, COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold [General function prediction only].	1.2971e-99
NZ_LN854556.1\|WP_048523903.1\|1996071_1997142_-\|DNA-polymerase-IV	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
NZ_LN854556.1\|WP_054189630.1\|1997388_1997919_-\|DUF3267-domain-containing-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	3.20825e-11
NZ_LN854556.1\|WP_000027928.1\|2002576_2004034_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_LN854556.1\|WP_000170162.1\|2004035_2004338_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.296e-34
NZ_LN854556.1\|WP_000831695.1\|2006782_2007982_-\|CamS-family-sex-pheromone-protein	gnl\|CDD\|227188	COG4851, CamS, Protein involved in sex pheromone biosynthesis [General function prediction only].	0
NZ_LN854556.1\|WP_000613738.1\|1995450_1996005_+\|3'-5'-exonuclease	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
NZ_LN854556.1\|WP_001165363.1\|2013054_2013357_-\|hypothetical-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	1.66593e-59

>NZ_LN854556.1|WP_054189628.1|1999530_2000478_-|diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAIHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>NZ_LN854556.1|WP_054189629.1|1998088_1999450_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNKVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEIVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>NZ_LN854556.1|WP_054189630.1|1997388_1997919_-|DUF3267-domain-containing-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQYEDSIYLYHQKPTQ
>NZ_LN854556.1|WP_048523903.1|1996071_1997142_-|DNA-polymerase-IV
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVRDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>NZ_LN854556.1|WP_000613738.1|1995450_1996005_+|3'-5'-exonuclease
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>NZ_LN854556.1|WP_001790679.1|1995141_1995234_-|hypothetical-protein
MTKNTIISLENEKTQINDSENESSDLRKAK
>NZ_LN854556.1|WP_000949467.1|1994559_1995060_+|H-type-ferritin-FtnA
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>NZ_LN854556.1|WP_054189631.1|1992954_1994268_-|lipid-II-isoglutaminyl-synthase-subunit-MurT
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIIERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>NZ_LN854556.1|WP_054189632.1|1992221_1992953_-|type-1-glutamine-amidotransferase
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVLEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>NZ_LN854556.1|WP_001790257.1|1992023_1992134_-|hypothetical-protein
MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT
>NZ_LN854556.1|WP_000545370.1|2001136_2002564_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLNGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
>NZ_LN854556.1|WP_000027928.1|2002576_2004034_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADVNDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
>NZ_LN854556.1|WP_000170162.1|2004035_2004338_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
>NZ_LN854556.1|WP_054189627.1|2004704_2006243_+|sodium/proline-symporter-PutP
MLTMGTALSQQVDTNWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTHQKEFVMIGRLSVLVVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
>NZ_LN854556.1|WP_000831695.1|2006782_2007982_-|CamS-family-sex-pheromone-protein
MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIATDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQDGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEKSPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVKKQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNEWHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRLVVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEPQVHIYSN
>NZ_LN854556.1|WP_054189626.1|2007994_2009998_-|NAD-dependent-DNA-ligase-LigA
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEYPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
>NZ_LN854556.1|WP_054189625.1|2010001_2012194_-|DNA-helicase-PcrA
MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANMNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNVKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
>NZ_LN854556.1|WP_000272064.1|2012190_2012883_-|heptaprenylglyceryl-phosphate-synthase
MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
>NZ_LN854556.1|WP_001165363.1|2013054_2013357_-|hypothetical-protein
MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLSQRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE
>NZ_LN854556.1|WP_054189624.1|2013464_2014760_-|adenylosuccinate-lyase
MIERYSREEMSKIWTDQNRYEAWLEVEILACEAWSELGHIPKADVQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTALSFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTEMQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDRHAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFRELIEQDESITSVLTKEELDECFDPKHHLNQVDTIFERAGLA

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Crispr_ID: NZ_LN854556_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN854556_4

2180330-2180425

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTTATGCAG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NZ_LN854556_4

>merge|NZ_LN854556|4|2180330-2180425|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGTAGCATCCAACTGTATTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTCTTATGCAG

>NZ_LN854556|4|4|2180330-2180425|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAG	TTGATGCGTAGCATCCAACTGTATTCCTCTATTTTT
CAACTTTAGTTGTTAGGGGCTCTTATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN854556.1\|WP_061745642.1\|2186682_2188221_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NZ_LN854556.1\|WP_054190818.1\|2190833_2191940_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NZ_LN854556.1\|WP_000220900.1\|2180521_2180614_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_054190811.1\|2177780_2178761_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NZ_LN854556.1\|WP_000334465.1\|2184196_2186002_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_LN854556.1\|WP_054190390.1\|2182776_2184093_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_LN854556.1\|WP_054190813.1\|2180761_2181619_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NZ_LN854556.1\|WP_054190817.1\|2190399_2190834_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NZ_LN854556.1\|WP_054190814.1\|2181686_2182469_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NZ_LN854556.1\|WP_054190805.1\|2170630_2171341_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_LN854556.1\|WP_054190812.1\|2179222_2180314_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_054190809.1\|2175265_2176204_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NZ_LN854556.1\|WP_054190806.1\|2171460_2171904_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NZ_LN854556.1\|WP_054190807.1\|2172103_2172517_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NZ_LN854556.1\|WP_054190808.1\|2175004_2175235_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_054190816.1\|2188255_2190388_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NZ_LN854556.1\|WP_000123402.1\|2172958_2174332_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NZ_LN854556.1\|WP_054190819.1\|2192258_2199596_-\|DUF1542-domain-containing-protein	unknown	unknown	gnl\|CDD\|275089
NZ_LN854556.1\|WP_000003759.1\|2177458_2177779_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_LN854556.1\|WP_054190810.1\|2176641_2177307_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554

Protein	Function_ID	Function_description	E-value
NZ_LN854556.1\|WP_061745642.1\|2186682_2188221_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NZ_LN854556.1\|WP_054190818.1\|2190833_2191940_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NZ_LN854556.1\|WP_054190811.1\|2177780_2178761_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	6.66959e-108
NZ_LN854556.1\|WP_000334465.1\|2184196_2186002_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_LN854556.1\|WP_054190390.1\|2182776_2184093_+\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.72695e-69
NZ_LN854556.1\|WP_054190813.1\|2180761_2181619_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	2.26647e-58
NZ_LN854556.1\|WP_054190817.1\|2190399_2190834_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	7.52983e-63
NZ_LN854556.1\|WP_054190814.1\|2181686_2182469_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	2.43842e-105
NZ_LN854556.1\|WP_054190805.1\|2170630_2171341_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	1.55756e-156
NZ_LN854556.1\|WP_054190806.1\|2171460_2171904_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.04833e-67
NZ_LN854556.1\|WP_054190809.1\|2175265_2176204_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	6.45152e-129
NZ_LN854556.1\|WP_054190807.1\|2172103_2172517_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	6.42561e-45
NZ_LN854556.1\|WP_054190816.1\|2188255_2190388_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	8.07378e-67
NZ_LN854556.1\|WP_000123402.1\|2172958_2174332_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NZ_LN854556.1\|WP_054190819.1\|2192258_2199596_-\|DUF1542-domain-containing-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.4008e-104
NZ_LN854556.1\|WP_000003759.1\|2177458_2177779_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NZ_LN854556.1\|WP_054190810.1\|2176641_2177307_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	9.04849e-48

>NZ_LN854556.1|WP_054190812.1|2179222_2180314_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYAFIAFAVIAVVYLLANFQLAKYSQTIAIYSQFGQKPPGDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMNHEKVKFTDLFIAFKKGIYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSFSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKLTKDKVKSADKNKKVVTEPKNTKVENEKVTTSVETKTEKAQDSLNDNTTNTMTSDKPEDNQPK
>NZ_LN854556.1|WP_054190811.1|2177780_2178761_+|CDF-family-zinc-efflux-transporter-CzrB
MSHPHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATATKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAIFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHNHDESIICSGTHSHSHNHHAHHHAHVH
>NZ_LN854556.1|WP_000003759.1|2177458_2177779_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NZ_LN854556.1|WP_054190810.1|2176641_2177307_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVAFTAGVRQTDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSIIASKEANIKHYVMVSTYDSRRQAFDDSCDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFENETD
>NZ_LN854556.1|WP_054190809.1|2175265_2176204_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEITNGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHRCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NZ_LN854556.1|WP_054190808.1|2175004_2175235_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISALLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NZ_LN854556.1|WP_000123402.1|2172958_2174332_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NZ_LN854556.1|WP_054190807.1|2172103_2172517_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDHIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NZ_LN854556.1|WP_054190806.1|2171460_2171904_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYTAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NZ_LN854556.1|WP_054190805.1|2170630_2171341_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKANNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NZ_LN854556.1|WP_000220900.1|2180521_2180614_+|hypothetical-protein
MTYGSIIAIVCALFVIFFIPYMEKNNKKKK
>NZ_LN854556.1|WP_054190813.1|2180761_2181619_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIVKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPVNGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKRNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMISHFGIKQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NZ_LN854556.1|WP_054190814.1|2181686_2182469_-|ABC-transporter-ATP-binding-protein
MLIQLDQVGRMKQGKTILKNISWQINEGDKWILYGLNGAGKTTLLNILNAYESVTSGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDALSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NZ_LN854556.1|WP_054190390.1|2182776_2184093_+|ISL3-family-transposase
MFNIILESFDLEDKNIVFEGKLEKIEYKGRRCFFYYAKLIYTPEVCPHCDCKNMNGNLIKNGTKTSRITMPKISEYPAYIMLSKQRFKCKTCERYFTAETPEVDKYCYISRRTRKSVINKSSEIRSEKSIAKSCSISGTTVSRIINEAAQSLHQSPYSALPEHIMMDEFKSVKNVSGKMSFIYADAQTHHIIDVVEDRRISELKKYFYRFSLEDRKQVKTVSIDMHEGYMTLIKEMFPNAKIVIDRFHIVQLLNRALNSIRVAVMNELRTTNQPLYNKFKRYAKLLLKPVEDLEAFEYRKVALFKEWKTQKGIVKYILDQDDSLNDAYQYINQLRFKLKHNDYEGFIHELKHMPLSQAHSIVQRAIKTLNKHEYFIKNTFEYYNLSNGPLEGINNKIKLIKRTSFGYGNYNHLRNRILLCSKLYAPKNKKEVKQSLVA
>NZ_LN854556.1|WP_000334465.1|2184196_2186002_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NZ_LN854556.1|WP_061745642.1|2186682_2188221_+|PTS-mannitol-transporter-subunit-IICB
MSQIEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIVGFKVLAPIMKFIMYILSVAVESLVHAHLLPVVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASCNVSETSSLDNDSEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NZ_LN854556.1|WP_054190816.1|2188255_2190388_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGEDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLEFDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQFDGIISTVNLEIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINNPTSFAELLEQRLIDNPGWILCPYPVAIPHLRDNMIKHPMILTTVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NZ_LN854556.1|WP_054190817.1|2190399_2190834_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGITLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NZ_LN854556.1|WP_054190818.1|2190833_2191940_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDNSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKNLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NZ_LN854556.1|WP_054190819.1|2192258_2199596_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAADQNQPVGANAQPTANAGTQADPNANQPAAPANQGQPVAQPANQGGQVDPNNAGQPQPANQAGQTAPAGGAVQPNAQPAGQGNQPDPNNVAQAQPANATVAQPAAPVPANAQAQDPNASNTGEGSINTTLTFDDPAITTDKNRQDPTVTVTDRLNDYSLINNGKIGFVNSELRRSDMFDKNSPQNYQARGNVAALGRVNANDPNNHGDFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIRDAKKNTELATVKVGRTGTAHLFKVPTDADRLDLQFIPDNTAVADATRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLEAKATNNKEYTINTEIGNNGNFGASLKANEFKYEVTLPQGVTYVNDSLTTAFPDGNDDSTVLKNMTVNYDQNANTLTFTSQGVTTARGTNTKEVLFPDKSLKISYKVNVANIATPQNINFNEKLTYRTASDVIVGNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILSEDANHVETANRASQADIDGLVTKLQAALINKQTAVSDLDTKAQEMITLANQNNKVTQDEKDALIVKINNDKNNAIAEINKQTTTQGVTTEKDKGIAVLEQDIITPNVKPQAKQAIIQAVTSRKQQIKKSTASIQEEKDVANRNIGNIETKAIKDIDLATTNAQVEAIRTKAINDINQTTPSTTAKTETLNEYNEVVQAQIDQAPLNPDSTTEEIQEAIQRINEAKEQGIKAIEATTNSQDLRTTKDNEIAKIENITNSTATKMAAYNEVKQAAAAKKATNGQTTNATDEEVAEASQAVDTAQTEGIKEIQGVKTNQEVADKKTEVINRINAIQPAVRVKPEAETAIENAYNIRKQEIQNSNASTTEEKEAAITQLDAKKQAATTAIDAETSNAGVTTAKENGINEINQIQAETTKKSEAKAAIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVTVANTEIDNAAANTDVDNAKTTNEALIAAITPDANVKPAAKQAITQKVQDQETAIDGNTGATTEEKNAAKQQVQAAKTAAENAIDAAHSNAEVEAAKNAEIAKIEAIQPATTTKDDAKQAIATKANERKATIAQTQDITAEEIEAANADVDNAVTQANNSIEAANSQNDVDQAKTTGEASIDQVTPTVNKKATARNEITTILNNKLQEIQATADATDEEKQAAETEANTENTKATQAVNVATTNAEVDKAKANAEAAINAVTPKVRKKRAALEEIDQLQVTQTQTINNEQNATNEEKEAALQQLTQAVTNAKNNINAATDNNGVDQAKDAGKNAIETTQPATAIKTNAKAEVDQAVNTQTQTIDNEQNATTEEKAAAKSLVDQAKTQAYEDILNAQTTNNVNQVKDQAVNDIQGITADTTIKDTAVQELTDKATEQNRIIDQENDSTTEEKQTATQQVNTALDTAKQNVTNANSIDEVNVAKDAGIESIEKIKPSTDTKNNARADLRTTYQNKVQAFLNDTNSTNEEKQAAIEKPREAFIIGIDGINKAKTNADVATAKMEAETKINQATVNGVKKPAAKNQLTNLADQRKVEIENTPNAQQQEIDAAKQEITDFLNVAQTEIDQANTNNDVDNAVTKATENINAVKTFGELKKDALAQIERAYNAKVTEADNSNTSTSNEIDEAKQKLAELKQQADQNINQTTAKDQLQAQLENGLSSINTYNIPSSKKETVTTELYGYADQKKNNIQADKQGTQNEKVIATNEVDEVVENTLERINNAVNNSDVDDALTQGKLAIDAVQVEAKVKPAAIKAIEDKANETIESINDSENLTKEEKAEALAEIKQIADQSKLDINNSATTTDVTAAKSRGLEAFDNIQIDSTKKQQAIEELENVLDRIEEKVDLNTDATTEEKEAFTNHLEDILSEALEDIYNQTTNDDIDTVKNQTIEKLNAQQFNPEVKKNALKAVEAAVSKQQEKINNTDSNKTAKENALNDLNSIRDRFVEDLTKTQSNAEIAELQNVTIPAIEAIVPQNDSDNNDATANSNANATPENTGQPNVPETTDNGKANASPTTPNTNNDATTGETTPSNNSSTEDANVKPTTNDNSSVDPATNGSATSNNATNNGTTDKPATETDNATPAESTTNNNSTTTATNENATTGSTATAPTKTESTETASSADSKDNASVNDSNQNAEVNNSPESQPTNGKVAQPKSENKAEAEKDDRDSTNQSMVESTTEILPSADITEPKVPSNTSKDKEESTTNQTDAEQHNSDTNVTSNEVDKSPSKADSEVSNKPSTSASSEAKDKMTTINVSQKDDMATADTKDTQTSVGSAANNKAKDMQTNDMKASLATVSNGSNSANQDMLNVTKADENKTNAKSAQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: NZ_LN854556_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LN854556_5

2445211-2445293

Orphan

Consensus_repeat	Method
GGGCCCCAACACAGAAGCTGGCGGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LN854556_5

>merge|NZ_LN854556|5|2445211-2445293|CRISPRCasFinder
GGGCCCCAACACAGAAGCTGGCGGCAGATCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGACGGCAG

>NZ_LN854556|5|5|2445211-2445293|CRISPRCasFinder
GGGCCCCAACACAGAAGCTGGCGGCAG	ATCAGCTTACAATAATGTGCAAGTTGGCG
GGGCCCCAACACAGAAGCTGACGGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LN854556.1\|WP_054189950.1\|2434171_2437861_-\|nitrate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|227346
NZ_LN854556.1\|WP_000448222.1\|2439138_2439453_-\|nitrite-reductase-small-subunit-NirD	unknown	unknown	gnl\|CDD\|239606
NZ_LN854556.1\|WP_054189946.1\|2442885_2443422_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379326
NZ_LN854556.1\|WP_000594640.1\|2445387_2446212_-\|formate/nitrite-transporter-family-protein	unknown	unknown	gnl\|CDD\|225027
NZ_LN854556.1\|WP_000934156.1\|2431384_2432062_-\|respiratory-nitrate-reductase-subunit-gamma	unknown	unknown	gnl\|CDD\|376889
NZ_LN854556.1\|WP_054189945.1\|2446414_2446597_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LN854556.1\|WP_000692645.1\|2432622_2434182_-\|nitrate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|224063
NZ_LN854556.1\|WP_054190390.1\|2443617_2444934_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|225995
NZ_LN854556.1\|WP_054189948.1\|2439456_2441862_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224171
NZ_LN854556.1\|WP_142241192.1\|2441889_2442657_-\|sirohydrochlorin-chelatase	unknown	unknown	gnl\|CDD\|225049
NZ_LN854556.1\|WP_054189937.1\|2452548_2453280_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LN854556.1\|WP_054189938.1\|2451203_2452454_+\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
NZ_LN854556.1\|WP_054189939.1\|2450585_2450948_-\|DUF4467-domain-containing-protein	unknown	unknown	gnl\|CDD\|291399
NZ_LN854556.1\|WP_054189943.1\|2447336_2448884_-\|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA	unknown	unknown	gnl\|CDD\|370371
NZ_LN854556.1\|WP_054189944.1\|2446683_2447151_-\|SRPBCC-domain-containing-protein	unknown	unknown	gnl\|CDD\|226353
NZ_LN854556.1\|WP_054189942.1\|2449177_2449444_-\|Txe/YoeB-family-addiction-module-toxin	unknown	unknown	gnl\|CDD\|284238
NZ_LN854556.1\|WP_054189949.1\|2438170_2439148_-\|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl\|CDD\|273643
NZ_LN854556.1\|WP_054189941.1\|2449443_2449695_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|225072
NZ_LN854556.1\|WP_054189940.1\|2449967_2450567_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NZ_LN854556.1\|WP_000606768.1\|2432054_2432630_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	unknown	unknown	gnl\|CDD\|225091

Protein	Function_ID	Function_description	E-value
NZ_LN854556.1\|WP_054189950.1\|2434171_2437861_-\|nitrate-reductase-subunit-alpha	gnl\|CDD\|227346	COG5013, NarG, Nitrate reductase alpha subunit [Energy production and conversion].	0
NZ_LN854556.1\|WP_000448222.1\|2439138_2439453_-\|nitrite-reductase-small-subunit-NirD	gnl\|CDD\|239606	cd03530, Rieske_NirD_small_Bacillus, Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium.	3.72601e-50
NZ_LN854556.1\|WP_054189946.1\|2442885_2443422_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379326	pfam13673, Acetyltransf_10, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.89933e-08
NZ_LN854556.1\|WP_000594640.1\|2445387_2446212_-\|formate/nitrite-transporter-family-protein	gnl\|CDD\|225027	COG2116, FocA, Formate/nitrite family of transporters [Inorganic ion transport and metabolism].	1.8788e-75
NZ_LN854556.1\|WP_000934156.1\|2431384_2432062_-\|respiratory-nitrate-reductase-subunit-gamma	gnl\|CDD\|376889	pfam02665, Nitrate_red_gam, Nitrate reductase gamma subunit. This family is the gamma subunit of the nitrate reductase enzyme, the gamma subunit is a b-type cytochrome that receives electrons from the quinone pool. It then transfers these via the iron-sulfur clusters of the beta subunit to the molybdenum cofactor found in the alpha subunit. The nitrate reductase enzyme, EC:1.7.99.4 catalyzes the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen.	5.77868e-110
NZ_LN854556.1\|WP_000692645.1\|2432622_2434182_-\|nitrate-reductase-subunit-beta	gnl\|CDD\|224063	COG1140, NarY, Nitrate reductase beta subunit [Energy production and conversion].	0
NZ_LN854556.1\|WP_054190390.1\|2443617_2444934_-\|ISL3-family-transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.72695e-69
NZ_LN854556.1\|WP_054189948.1\|2439456_2441862_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224171	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion].	0
NZ_LN854556.1\|WP_142241192.1\|2441889_2442657_-\|sirohydrochlorin-chelatase	gnl\|CDD\|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	9.56832e-71
NZ_LN854556.1\|WP_054189937.1\|2452548_2453280_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	2.48344e-144
NZ_LN854556.1\|WP_054189938.1\|2451203_2452454_+\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_LN854556.1\|WP_054189939.1\|2450585_2450948_-\|DUF4467-domain-containing-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	1.52722e-30
NZ_LN854556.1\|WP_054189943.1\|2447336_2448884_-\|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA	gnl\|CDD\|370371	pfam09223, ZinT, ZinT (YodA) periplasmic lipocalin-like zinc-recruitment. ZinT plays a critical role in recruiting periplasmic zinc to the bacterial zinc-uptake complex ZnuABC, consisting of families pfam01297,pfam00950, pfam00005, regulated by the transcription-regulator FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), pfam01297. Members of this family of prokaryotic domains were first identified as part of the response of bacteria to a challenge with the toxic heavy metal cadmium. They are able to bind to cadmium, and ensure its subsequent elimination.	1.34776e-101
NZ_LN854556.1\|WP_054189944.1\|2446683_2447151_-\|SRPBCC-domain-containing-protein	gnl\|CDD\|226353	COG3832, COG3832, Uncharacterized conserved protein [Function unknown].	1.10132e-32
NZ_LN854556.1\|WP_054189942.1\|2449177_2449444_-\|Txe/YoeB-family-addiction-module-toxin	gnl\|CDD\|284238	pfam06769, YoeB_toxin, YoeB-like toxin of bacterial type II toxin-antitoxin system. YoeB_toxin is a family of bacterial toxins that forms one component of the type II toxin-antitoxin system in E. coli whose antitoxin is represented by YefM, found in pfam02604. The plasmid encoded Axe-Txe proteins in Enterococcus faecium act as an antitoxin-toxin pair. When the plasmid is lost, the antitoxin is degraded relatively quickly by host enzymes. This allows the toxin to interact with its intracellular target, thus killing the cell or impeding cell growth. These toxins are highly potent protein synthesis inhibitors, specifically blocking the initiation of translation. In the case of YoeB, it binds to the 50 S ribosomal subunit in 70 S ribosomes and interacts with the A site leading to mRNA cleavage at this site. As a result, the 3'-end portion of the mRNA is released from ribosomes, and translation initiation is effectively inhibited.	2.5207e-44
NZ_LN854556.1\|WP_054189949.1\|2438170_2439148_-\|uroporphyrinogen-III-C-methyltransferase	gnl\|CDD\|273643	TIGR01469, Uroporphyrinogen-III_C-methyltransferase, uroporphyrin-III C-methyltransferase. This model represents enzymes, or enzyme domains, with uroporphyrin-III C-methyltransferase activity. This enzyme catalyzes the first step committed to the biosynthesis of either siroheme or cobalamin (vitamin B12) rather than protoheme (heme). Cobalamin contains cobalt while siroheme contains iron. Siroheme is a cofactor for nitrite and sulfite reductases and therefore plays a role in cysteine biosynthesis; many members of this family are CysG, siroheme synthase, with an additional N-terminal domain and with additional oxidation and iron insertion activities. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	2.80475e-119
NZ_LN854556.1\|WP_054189941.1\|2449443_2449695_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|225072	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	1.81826e-20
NZ_LN854556.1\|WP_054189940.1\|2449967_2450567_-\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	1.22498e-30
NZ_LN854556.1\|WP_000606768.1\|2432054_2432630_-\|nitrate-reductase-molybdenum-cofactor-assembly-chaperone	gnl\|CDD\|225091	COG2180, NarJ, Nitrate reductase delta subunit [Energy production and conversion].	1.19436e-65

>NZ_LN854556.1|WP_054190390.1|2443617_2444934_-|ISL3-family-transposase
MFNIILESFDLEDKNIVFEGKLEKIEYKGRRCFFYYAKLIYTPEVCPHCDCKNMNGNLIKNGTKTSRITMPKISEYPAYIMLSKQRFKCKTCERYFTAETPEVDKYCYISRRTRKSVINKSSEIRSEKSIAKSCSISGTTVSRIINEAAQSLHQSPYSALPEHIMMDEFKSVKNVSGKMSFIYADAQTHHIIDVVEDRRISELKKYFYRFSLEDRKQVKTVSIDMHEGYMTLIKEMFPNAKIVIDRFHIVQLLNRALNSIRVAVMNELRTTNQPLYNKFKRYAKLLLKPVEDLEAFEYRKVALFKEWKTQKGIVKYILDQDDSLNDAYQYINQLRFKLKHNDYEGFIHELKHMPLSQAHSIVQRAIKTLNKHEYFIKNTFEYYNLSNGPLEGINNKIKLIKRTSFGYGNYNHLRNRILLCSKLYAPKNKKEVKQSLVA
>NZ_LN854556.1|WP_054189946.1|2442885_2443422_-|GNAT-family-N-acetyltransferase
MTNTTIRLANENDAETLHQLMYKAFTPLRELGIDWPSVNANLDAVKENIDKNTTFVMTIDDEIISTITVRYPWGSVKSISGYPFVWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAAVTLGTSARLHPWLLKIYEKRGYEIYSEHENDDGDLGVIMRKVLIPERFDEKILGQPPF
>NZ_LN854556.1|WP_142241192.1|2441889_2442657_-|sirohydrochlorin-chelatase
MNGNIIVAHGMRRGRQNQALEAFISELVKDDIHHYDIAFLESEHQDLETVMTTLVQSGVDHFKIVPLLIFSAMHYLKDIPNIVHEMKRRYPDIKVEVSEPLGTHPLMKRLIEQRICDALEGDEQQVGVMVVAHGNINGKFTKAHEELQICAQNLQISKATYARTLYGEISFIHDLESISKRYQKLIVVPLFLYDGRLVNKVKQQMNDMVINTDIYITPSINFDPILKQIINDRLESLNDSNENIKAQTKIKTFLK
>NZ_LN854556.1|WP_054189948.1|2439456_2441862_-|NAD(P)/FAD-dependent-oxidoreductase
MAKQKLVMIGNGMAGIRTIEEILERANDLYDITVIGKEPYPNYNRIMLSNILQNKMTVEETIMNPYEWYEENAIELITNDPVIEVDRANQSVTTANGIEVSYDKLIFATGSKAFVIPVPGSTLPSVIGWRTIDDTEQMMNIAKTKKKAIVIGGGLLGLECARGLLDQGMEVTVLHLAEWLMEMQLDRKAGNMLKADLEKQGMKFEMQANTTEILGEDDVEGVKLADGREIPADLVVMAVGIRPYTEVAKESGLDVNRGIVVNDIMQTSDDNVYAVGECAEHNGKVYGLVAPLYEQGKVLADHLTDKETKGYKGSTTFTSLKVSGCDLYSAGQIVENAEIKGIEIFNSVDNNYKKVFLKDGNVVGAVLYGDIDDGSRFYNMMKKGESTEDYTLVSLLTKGGEEATLSIADMADDETICGCNGVDKGTIVNAITENGFTTVEEVTAKTKAGNSCGKCKPQIAQILQHTLGDDFVAAKPAGICGCTDLTRDQIVTQIRAKGLKTSKEVRHVLNFKNKGGCPKCRPAINYYLNMVYPHDHEDERESRFANERYHANIQNDGTFSVIPQMRGGVTDADQLIRLGEVAKKYNVPLVKVTGSQRVGLYGVKKEELPNIWEDLGMRSASAYGKKTRSVKSCVGKEFCRFGTQYTTRLGIRLEKTFEYIDTPHKFKMGVSGCPRSCVESGVKDFGIISVENGFQIYIGGNGGTEVEKAEFLTTVETEDEVIKLCGALMQYYRETGIYAERTAPWLRRLGFENVKEVLLNPERQNELFERIMDAKKAVEAEPWEAITSNAQARKIFEVEKV
>NZ_LN854556.1|WP_000448222.1|2439138_2439453_-|nitrite-reductase-small-subunit-NirD
METKEKIKVTTIDELTPLIGKKVIVKGKEVGLFLTESGKIHAIHNICPHKQGPLSEGTVSGEYVFCPLHDQKIDLNTGIVQEPDEGCVDVYEVEVTDGNVYICL
>NZ_LN854556.1|WP_054189949.1|2438170_2439148_-|uroporphyrinogen-III-C-methyltransferase
MSVDEYGKVYLIGAGPGNPNYLTKKAERLIREADVILYDRLVNPLILQYANLTTEIIDVGKKPYAKHIQQEKINDCIVEAARRYNKVVRLKGGDPAIFGRVQEEVDTLNNFNIAFEIVPGVTSASAAVATMQTGLTMRTVAKSVTFSTGHFKDSEENEVDVNSLVNGGTLAIYMGVKRLGKIITQIQQYTDIDYPIAIVFQASCFNEFVVKGRLSNIISKLQHYSIEAKPGICIIGEVVGYTENTPKSYDPTKQFYVVSGSKHDALMLCEHLYDEGYGCLLNPNDTSNGTYHSSQYDYYDAFIKQQENVTYISTDHADANTVLCH
>NZ_LN854556.1|WP_054189950.1|2434171_2437861_-|nitrate-reductase-subunit-alpha
MGKFGLNFFKPTEKFNGNWSILESKSREWEKMYRERWSHDKEVRTTHGVNCTGSCSWKVFVKNGVITWENQQTDYPSCGPDMPEYEPRGCPRGASFSWYEYSPLRIKYPYIRGKLWDLWTEALEENNGNRVAAWASIVENEDKAKQYKQARGMGGHVRSNWKDVTEIIAAQLLYTIKKYGPDRIAGFTPIPAMSMISYAAGARFINLLGGEMLSFYDWYADLPPASPQIWGEQTDVPESSDWYNASYIIMWGSNVPLTRTPDAHFMTEVRYKGTKVISVAPDYAENVKFADNWLAPNPGSDAAIAQAMTHVILQEHYVNQPNERFINYAKQYTDMPFLIMLDEDENGYKAGRFLRASDLGQTTEQGEWKPVIHDAISDSLVVPNGTMGQRWEEGKKWNLKLETEDGSKINPTLSMTEGGYELETIQFPYFDSDGDGIFNRPIPTRQVTLANGDKVRIATIFDLMASQYGVRRFDHKLESKGYADAESKYTPAWQEAISGVKQSVVIQVAKEFAQNAIDTEGRSMIIMGAGINHWFNSDTIYRSILNLVMLCGCQGVNGGGWAHYVGQEKCRPIEGWSTVAFAKDWQGPPRLQNGTSWFYFATDQWKYEESNVDRLKSPLAKTEELKHQHPADYNVLAARLGWLPSYPQFNKNSLLFAEEAKDEGIESNEAILQRAIDEVKSKQTQFAIEDPDLKKNHPKSLFIWRSNLISSSAKGQEYFMKHLLGTKSGLLATPNEDEKPEEITWREETTGKLDLVVSLDFRMTATPLYSDIVLPAATWYEKHDLSSTDMHPYVHPFNPAIDPLWESRSDWDIYKTLAKAFSEMAKDYLPGTFKDVVTTPLSHDTKQEISTPYGVVKDWSKGEIEAVPGRTMPNFAIVERDYTKIYDKYVTLGPVLEKGKVGAHGVSFGVSEQYEELKSMLGTWSDTNGDSIKANRPRIDTARNVADAILNISSATNGKLSQKSYEDLEEQTGMPLKDISRERAAEKISFLNITSQPREVIPTAVFPGSNKEGRRYSPFTTNVERLVPFRTLTGRQSYYVDHEVFQQFGESLPVYKPTLPPMVFGNRDKKIKGGTDALVLRYLTPHGKWNIHSMYQDNKHMLTLFRGGPTVWISNEDAEKHDIQDNDWLEVYNRNGVVTARAVISHRMPKGTMFMYHAQDKHIQTPGSEITDTRGGSHNAPTRIHLKPTQLVGGYAQISYHFNYYGPIGNQRDLYVAVRKMKEVNWLED
>NZ_LN854556.1|WP_000692645.1|2432622_2434182_-|nitrate-reductase-subunit-beta
MKIKAQVAMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVETKPGVGYPKRWEDQEHYKGGWVLNRKGKLELKSGSRISKIALGKIFYNPDMPLIKDYYEPWNYNYEHLTTAKSGKHSPVARAYSEITGDNIEIEWGPNWEDDLAGGHVTGPKDPNIQKIEEDIKFQFDETFMMYLPRLCEHCLNPSCVASCPSGAMYKRDEDGIVLVDQDACRGWRYCMTGCPYKKVYFNWKTNKAEKCTFCFPRIEAGMPTVCSETCTGRMRYLGVLLYDADRVHEAASAVDEKDLYEKQLDIFLNPFDEEVIAQAEKDGIGYDWIEAAQNSPIYKLAIEYKLAFPLHPEFRTMPMVWYCPPLSPIMSYFEGKNTTQNPDAIFPAIEEMRLPIEYLANIFTAGDTEPVKGALQRMAMMRSYMRSQVTQQPFDTSRLERLGITERQTKDMYRLLGLAKYEDRFVIPTSHKETYLDTYHAQGSTGYNYGGEHFGDNCEGCGVAVGSGKTGQEIYNENFYGGIFRD
>NZ_LN854556.1|WP_000606768.1|2432054_2432630_-|nitrate-reductase-molybdenum-cofactor-assembly-chaperone
MINFDNFKKYQESFGYMAQQLCFPEKLTFHPKTFEETISKDHPAYEDLVAFRNVMMTFSLSEIKAIYTDTFDFTKKAPLYMTYNKFDTQKERGQMLAKLKVLYEMFGLEMVDNELSDYLPLMLQFLQVAEWRNDPRAEENIQLIIMIIEDGTYVMANALGEDNNPYAYVIQALRKTLKLCLTSPKGVKHHA
>NZ_LN854556.1|WP_000934156.1|2431384_2432062_-|respiratory-nitrate-reductase-subunit-gamma
MLNQFLWVIFPYLCLVVFVAGHIARYRYDKFSWTAKSSELIERKRLMWGSLLFHLGIIPVFFGHVVGLLIPKSWMDAVGVSEHLYHIGAVYIGSIFGIITLVGMFLLTARRVTTKSIRRLSSASDIFVNFLLLLIVFMGCYATLVTNIQHPDFNYRTSLSIWFRQLFMLKPDASLMSGVPIAFKMHILLGFTIMACWPFTRLVHVWSVPLTYINRRYIIYRKNKV
>NZ_LN854556.1|WP_000594640.1|2445387_2446212_-|formate/nitrite-transporter-family-protein
MIKNNKTVEDTYSTKAIVDSISSSVQMKQVMVQQTPGRYMLKSMMAGFLLSIVTVFMFGIKTQFASTHVDGLINLMGAIAFSLGLVLVVLTNSELLTSNFMYFTVGWYYKVVSLNKMMWILLYCFLGNILGGFVLFFLMKYAHVMTPEMTQALTALVQKKTVDSTWLNIFTKGIFCNFFINIGIFISMQFKGGLTKAFFIACGVIVFVYMGYEHVVFNAGLYAGMVFFNLDAVSWLHVLKNIVFAFLGNFVGGGIFVGLVYAFLNGKRNRLEQQ
>NZ_LN854556.1|WP_054189945.1|2446414_2446597_-|hypothetical-protein
MAQRYIKVLILYIFTTLLSSITVTSKCVPNKVVRFILRTLVGYGIFAYGLHYFSNLKKNK
>NZ_LN854556.1|WP_054189944.1|2446683_2447151_-|SRPBCC-domain-containing-protein
MTIKVEDNKIIFSRTIEAPIEKVFDAYTTKVLFEKWFHPKDASTKVFRFNAVSGGDAFYAIKTPTMTSYTLAEYKTVKRPYLIEYIDSFATPQGAKDTKMPSMKITLSFSEFDTTKTTVTSTSVFPTKEAAQQVINMGVEQGMNQTLDQLDALLK
>NZ_LN854556.1|WP_054189943.1|2447336_2448884_-|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA
MKKKLGMLLLVPAVTLSLAACGNDDGKDKDGKVTIKTTVYPLQSFAEQIGGKHVKVSSIYPAGTDLHSYEPTQKDILSASKSDLFMYTGDNLDPVAKKVASTIKDKDKKLSLEDKLDKAKLLTDQHEHGEEHEHEGHNHEKEEHHHHGGYDPHVWLDPKINQTFAKEIKDELVKKDPKHKDDYEKNYKKLNDDLKKIDNDMKQVTKDKQGNAVFISHESIGYLADRYGFVQKGIQNMNAEDPSQKELTKIVKEIRDSNAKYILYEDNVANKVTETIRKETDAKPLKFYNMESLNKEQQKKDNITYQSLMKSNIENIGKALDSGVKVKDDKAESKHDKAISDGYFKDEQVKDRELSDYAGEWQSVYPYLKDGTLDEVMEHKAENDPKKSAKDLKAYYDKGYKTNITNIDIKGNEITFTKDGKKHTGKYEYNGKKTLKYPKGNRGVRFMFKLVDGNDKDLPKFIQFSDHNIAPKKAEHFHIFMGNDNDALLKEMDNWPTYYPSKLNKDQIKEEMLAH
>NZ_LN854556.1|WP_054189942.1|2449177_2449444_-|Txe/YoeB-family-addiction-module-toxin
MARLNITFSPQAFEDYKYFQQNDKKMALKINELLKSIDRNGALKGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIKIASCKYHY
>NZ_LN854556.1|WP_054189941.1|2449443_2449695_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTIMKDIDV
>NZ_LN854556.1|WP_054189940.1|2449967_2450567_-|DsbA-family-protein
MTKKLLTLFIVSMLILTACGKKESATTSTKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTEELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>NZ_LN854556.1|WP_054189939.1|2450585_2450948_-|DUF4467-domain-containing-protein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIIIAYKPLSNDDEVHYYAYDFSDKRVSYKKDFDSRRYYQQHDADYHEENMTN
>NZ_LN854556.1|WP_054189938.1|2451203_2452454_+|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTIKNFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETPTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALKESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSNSSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPLLYKVKTHLNHKRR
>NZ_LN854556.1|WP_054189937.1|2452548_2453280_-|amino-acid-ABC-transporter-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEAREKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPNVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	283337-283364	0	1.0
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	739208-739235	0	1.0
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	780135-780162	0	1.0
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	902378-902405	0	1.0
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	831356-831383	1	0.964
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	831411-831438	1	0.964
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	1618700-1618727	1	0.964
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	1618755-1618782	1	0.964
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	2689477-2689504	1	0.964
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	1906900-1906926	1	0.963
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	240941-240968	2	0.929
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	1989495-1989522	2	0.929
NZ_LN854556_1	1.1\|748698\|28\|NZ_LN854556\|CRISPRCasFinder	748698-748725	28	NZ_LN854556.1	1989666-1989693	2	0.929
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	138482-138508	2	0.926
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	319960-319986	2	0.926
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	320016-320042	2	0.926
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	1618783-1618809	2	0.926
NZ_LN854556_3	3.1\|2000642\|27\|NZ_LN854556\|CRISPRCasFinder	2000642-2000668	27	NZ_LN854556.1	1989752-1989778	2	0.926

1. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 283337-283364, mismatch: 0, identity: 1.0

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcgaaa	Protospacer
****************************

2. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 739208-739235, mismatch: 0, identity: 1.0

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcgaaa	Protospacer
****************************

3. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 780135-780162, mismatch: 0, identity: 1.0

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcgaaa	Protospacer
****************************

4. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 902378-902405, mismatch: 0, identity: 1.0

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcgaaa	Protospacer
****************************

5. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 831356-831383, mismatch: 1, identity: 0.964

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacatagagaatttcgaaa	Protospacer
*************.**************

6. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 831411-831438, mismatch: 1, identity: 0.964

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacatagagaatttcgaaa	Protospacer
*************.**************

7. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 1618700-1618727, mismatch: 1, identity: 0.964

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcaaaa	Protospacer
************************.***

8. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 1618755-1618782, mismatch: 1, identity: 0.964

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacacagagaatttcaaaa	Protospacer
************************.***

9. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 2689477-2689504, mismatch: 1, identity: 0.964

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacatagagaatttcgaaa	Protospacer
*************.**************

10. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 1906900-1906926, mismatch: 1, identity: 0.963

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttacattgtttgtagaaattgg	Protospacer
*************.*************

11. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 240941-240968, mismatch: 2, identity: 0.929

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaatacagagaaattcgaaa	Protospacer
***********.******** *******

12. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 1989495-1989522, mismatch: 2, identity: 0.929

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggccccaacatagagaatttcaaaa	Protospacer
*************.**********.***

13. spacer 1.1|748698|28|NZ_LN854556|CRISPRCasFinder matches to position: 1989666-1989693, mismatch: 2, identity: 0.929

cggggccccaacacagagaatttcgaaa	CRISPR spacer
cggggacccaacacagagaatttcaaaa	Protospacer
***** ******************.***

14. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 138482-138508, mismatch: 2, identity: 0.926

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttgcattgtttgtagaaattgg	Protospacer
*******.*****.*************

15. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 319960-319986, mismatch: 2, identity: 0.926

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttgcattgcttgttgaaattgg	Protospacer
*******.********** ********

16. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 320016-320042, mismatch: 2, identity: 0.926

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttgcattgcttgttgaaattgg	Protospacer
*******.********** ********

17. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 1618783-1618809, mismatch: 2, identity: 0.926

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttgcattgtttgtagaaattgg	Protospacer
*******.*****.*************

18. spacer 3.1|2000642|27|NZ_LN854556|CRISPRCasFinder matches to position: 1989752-1989778, mismatch: 2, identity: 0.926

ccaacttacattgcttgtagaaattgg	CRISPR spacer
ccaacttgcattgcctgtagaaattgg	Protospacer
*******.******.************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP016461	Blastomonas sp. RAC04 plasmid pBSY18_4, complete sequence	14338-14364	4	0.852
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP017942	Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence	343070-343096	5	0.815
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	114282-114308	5	0.815
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP024424	Paracoccus yeei strain TT13 plasmid pTT13-2, complete sequence	24508-24534	6	0.778
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP020440	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed2, complete sequence	135824-135850	6	0.778
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP044082	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence	186855-186881	6	0.778
NZ_LN854556_2	2.1\|968066\|27\|NZ_LN854556\|CRISPRCasFinder	968066-968092	27	NZ_CP031080	Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence	78487-78513	6	0.778

1. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP016461 (Blastomonas sp. RAC04 plasmid pBSY18_4, complete sequence) position: , mismatch: 4, identity: 0.852

cagaagctggcggaaagtcagcataaa	CRISPR spacer
gaaaagctagcggacagtcagcataaa	Protospacer
 *.*****.***** ************

2. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP017942 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.815

cagaagctggcggaaagtcagcataaa	CRISPR spacer
cagacgctggcggaaaggcagcaaatg	Protospacer
**** ************ ***** * .

3. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 5, identity: 0.815

cagaagctggcggaaagtcagcataaa	CRISPR spacer
aagaagctggcggaacttcagcattag	Protospacer
 **************  ******* *.

4. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP024424 (Paracoccus yeei strain TT13 plasmid pTT13-2, complete sequence) position: , mismatch: 6, identity: 0.778

cagaagctggcggaaagtcagcataaa	CRISPR spacer
gagaagctggcggaaagtcaggtctag	Protospacer
 ********************  . *.

5. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP020440 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

cagaagctggcggaaagtcagcataaa	CRISPR spacer
gagaagctggcggaaagtcaggtctag	Protospacer
 ********************  . *.

6. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP044082 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.778

cagaagctggcggaaagtcagcataaa	CRISPR spacer
gagaagctggcggaaagtcaggtctag	Protospacer
 ********************  . *.

7. spacer 2.1|968066|27|NZ_LN854556|CRISPRCasFinder matches to NZ_CP031080 (Paracoccus yeei strain CCUG 32053 plasmid pYEE2, complete sequence) position: , mismatch: 6, identity: 0.778

cagaagctggcggaaagtcagcataaa	CRISPR spacer
gagaagctggcggaaagtcaggtctag	Protospacer
 ********************  . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

611941 : 659962

Staphylococcus_phage(95.38%)

holin,terminase,portal,integrase,tail,protease,head,capsid

attL 612323:612339|attR 617456:617472

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031792587.1\|611941_613669_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.4e-110	43.5
612323:612339	attL	NA	NA	NA	NA
WP_054189189.1\|614028_615258_+	nucleoside permease	NA	NA	NA	NA
WP_054190606.1\|615541_616579_-\|integrase	site-specific integrase	A0A1X9H022	Staphylococcus_phage	8.5e-178	99.4
WP_000391618.1\|616751_617291_-	type II toxin-antitoxin system PemK/MazF family toxin	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
WP_000705238.1\|617430_617598_-	hypothetical protein	Q4ZDJ4	Staphylococcus_virus	1.7e-24	100.0
617456:617472	attR	NA	NA	NA	NA
WP_001089804.1\|617797_617983_-	hypothetical protein	A0A2I6PDS4	Staphylococcus_phage	2.3e-25	100.0
WP_001049399.1\|617969_618125_-	hypothetical protein	A0A2I6PDR9	Staphylococcus_phage	6.3e-21	100.0
WP_000094093.1\|618136_618844_-	helix-turn-helix transcriptional regulator	G4KNM8	Staphylococcus_phage	7.7e-130	100.0
WP_000548578.1\|619014_619254_+	helix-turn-helix transcriptional regulator	G4KNM9	Staphylococcus_phage	2.3e-38	100.0
WP_000435341.1\|619266_619527_+	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_054190605.1\|619550_620090_-	hypothetical protein	A7TW92	Staphylococcus_phage	6.5e-97	99.4
WP_001148618.1\|620146_620899_+	phage antirepressor KilAC domain-containing protein	A0A1X9H0A0	Staphylococcus_phage	8.7e-140	100.0
WP_000388066.1\|620915_621110_+	hypothetical protein	A0A1X9H0A2	Staphylococcus_phage	1.5e-19	100.0
WP_000939496.1\|621140_621281_+	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_000275058.1\|621295_621928_-	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_001120197.1\|621986_622307_+	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000066020.1\|622303_622465_+	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_000291489.1\|622557_622818_+	DUF1108 family protein	A0A1W6JQ03	Staphylococcus_phage	7.6e-43	100.0
WP_001205732.1\|622826_623090_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000700562.1\|623098_625042_+	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	99.2
WP_031764964.1\|625043_625964_+	recombinase RecT	A0A2I6PDH5	Staphylococcus_phage	3.0e-166	99.7
WP_071621397.1\|626044_626662_+	MBL fold metallo-hydrolase	S4SWA4	Staphylococcus_phage	9.1e-87	100.0
WP_000934770.1\|626662_627133_+	single-stranded DNA-binding protein	A0A0E3T9H6	Staphylococcus_phage	4.8e-80	99.4
WP_061745591.1\|627162_628047_+	DnaD domain protein	S4V6D4	Staphylococcus_phage	6.9e-136	95.6
WP_000338528.1\|628053_628272_+	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000401964.1\|628280_628685_+	RusA family crossover junction endodeoxyribonuclease	A0A0E3XBN4	Staphylococcus_phage	1.4e-72	100.0
WP_000101274.1\|628697_629066_+	hypothetical protein	W5RAK8	Staphylococcus_phage	8.2e-51	100.0
WP_000131366.1\|629069_629312_+	hypothetical protein	A0EWX8	Staphylococcus_phage	3.9e-41	100.0
WP_000982711.1\|629376_629826_+	hypothetical protein	A0A2I6PDH2	Staphylococcus_phage	2.1e-80	99.3
WP_001105598.1\|629822_630332_+	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	3.2e-93	100.0
WP_000197968.1\|630328_630739_+	hypothetical protein	A0A1X9H0B8	Staphylococcus_phage	2.3e-70	100.0
WP_015581851.1\|630731_631220_+	DUF1024 family protein	A0A0H3U313	Staphylococcus_phage	5.8e-12	54.3
WP_001066444.1\|631212_631749_+	dUTP diphosphatase	A0A1X9H0S5	Staphylococcus_phage	1.4e-96	100.0
WP_000195820.1\|631785_631992_+	DUF1381 domain-containing protein	A0A1X9H0C2	Staphylococcus_phage	1.3e-21	100.0
WP_000595265.1\|631988_632138_+	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000265041.1\|632137_632338_+	DUF1514 family protein	R9QT57	Staphylococcus_phage	1.1e-28	100.0
WP_000590126.1\|632365_632782_+	hypothetical protein	A0A1X9H0U8	Staphylococcus_phage	2.9e-76	100.0
WP_000988336.1\|633013_633313_+	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000402904.1\|633442_633787_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000625088.1\|633783_635445_+\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000025274.1\|635460_636648_+\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000861914.1\|636631_637369_+\|protease	Clp protease ClpP	C8CH20	Staphylococcus_phage	2.3e-129	100.0
WP_000154555.1\|637392_638538_+\|capsid	phage major capsid protein	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
WP_000238236.1\|638557_638842_+	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000150936.1\|638831_639116_+\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000755150.1\|639099_639462_+\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000114225.1\|639458_639863_+	HK97 gp10 family phage protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
WP_000565498.1\|639859_640267_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000268741.1\|640267_640912_+\|tail	phage tail protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
WP_072050172.1\|640953_641178_+	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	8.8e-32	98.6
WP_001096355.1\|641227_641578_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_001549167.1\|641628_641766_+	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
WP_054190603.1\|641822_646352_+\|tail	phage tail tape measure protein	A0A1X9H084	Staphylococcus_phage	0.0e+00	99.4
WP_000567408.1\|646348_647833_+\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_000582158.1\|647848_651634_+	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.4
WP_001153681.1\|651623_651776_+	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_001040261.1\|651822_652110_+	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_000539688.1\|652167_652464_+	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_077446684.1\|652615_652792_+\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	1.2e-20	93.1
WP_001791821.1\|652844_652952_-	hypothetical protein	NA	NA	NA	NA
WP_000611512.1\|653003_653258_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|653269_654025_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000919350.1\|654215_654707_+	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_000702262.1\|656200_656551_+	complement inhibitor SCIN-A	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
WP_001791826.1\|656603_656864_-	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000669789.1\|657174_657354_-	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001788321.1\|657781_657874_+	hypothetical protein	NA	NA	NA	NA
WP_054189190.1\|658050_658884_+	YitT family protein	NA	NA	NA	NA
WP_054193623.1\|659164_659962_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-18	30.7

DBSCAN-SWA_2

717544 : 725364

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054189238.1\|717544_718600_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	1.2e-14	30.2
WP_000149344.1\|718599_719286_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|719260_719734_-	DoxX family protein	NA	NA	NA	NA
WP_001093556.1\|720075_720516_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_054189239.1\|720795_721380_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|721478_722192_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|722195_722615_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_054189240.1\|722616_723285_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.3e-65	57.5
WP_054189241.1\|723635_724229_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.5e-38	42.9
WP_054189242.1\|724212_725364_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	1.6e-23	36.1

DBSCAN-SWA_3

737334 : 751777

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054189251.1\|737334_738393_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.4e-21	26.4
WP_000197261.1\|738550_739093_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_054189252.1\|739643_740561_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.7e-07	22.4
WP_061745593.1\|740842_742348_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	3.0e-59	32.2
WP_054189254.1\|742688_743189_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_054189255.1\|743208_744075_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|744875_745274_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_054189256.1\|745236_747342_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562498.1\|747459_748431_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000876318.1\|749104_750076_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|750062_751019_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_054189257.1\|751015_751777_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	29.6

DBSCAN-SWA_4

925029 : 966267

Streptococcus_phage(60.0%)

transposase,holin,bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054190364.1\|925029_926019_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_000258003.1\|926313_926709_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_054190363.1\|927079_927799_+	adaptor protein MecA	NA	NA	NA	NA
WP_054190362.1\|927919_928906_+	competence protein CoiA	NA	NA	NA	NA
WP_000082725.1\|928953_930762_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
WP_054190361.1\|931221_932028_-	DsbA family protein	NA	NA	NA	NA
WP_000214067.1\|932050_932416_-	truncated hemoglobin	NA	NA	NA	NA
WP_054190360.1\|932519_933113_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_054190359.1\|933298_933646_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|933662_934298_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|934314_935124_+	NAD kinase	NA	NA	NA	NA
WP_054190358.1\|935120_935975_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_054193581.1\|935995_937381_+	magnesium transporter	NA	NA	NA	NA
WP_054190356.1\|937390_939235_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_000933200.1\|939510_940281_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933103.1\|940465_941551_-	AI-2E family transporter	NA	NA	NA	NA
WP_054190355.1\|941892_943461_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_054190354.1\|943605_944364_+	esterase family protein	NA	NA	NA	NA
WP_000600387.1\|944557_945067_+	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_054190353.1\|945179_946370_-	MFS transporter	NA	NA	NA	NA
WP_054190352.1\|946347_947523_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_054190351.1\|947955_949440_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_077446587.1\|949420_949681_+	YueH family protein	NA	NA	NA	NA
WP_001049957.1\|949680_951243_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	2.2e-36	28.2
WP_000928413.1\|951544_952348_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_077446588.1\|952572_954885_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.8
WP_054190348.1\|954901_956260_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_054190347.1\|956398_957910_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_054190390.1\|958056_959373_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.4e-45	33.1
WP_000287265.1\|959895_960465_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|960674_960893_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_054190346.1\|960981_961968_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|962166_962343_+	YkvS family protein	NA	NA	NA	NA
WP_001033867.1\|962357_962960_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_099119695.1\|963259_963337_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_054190345.1\|963974_964259_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_054190344.1\|964302_966267_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA

DBSCAN-SWA_5

998480 : 1006953

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054190322.1\|998480_998963_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.6e-22	44.7
WP_054190321.1\|998949_1000074_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_054190320.1\|1000077_1000782_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	3.3e-48	42.5
WP_054190319.1\|1000781_1001045_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_054190318.1\|1001046_1001718_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_054190317.1\|1001710_1003900_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.1e-140	39.7
WP_054190316.1\|1003878_1005363_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000030811.1\|1005355_1006384_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_000238670.1\|1006386_1006953_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1

DBSCAN-SWA_6

1260178 : 1266071

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001807853.1\|1260178_1260376_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	9.9e-11	50.0
WP_077446765.1\|1261064_1261289_+	hypothetical protein	A0A1W6JNK0	Staphylococcus_phage	1.3e-19	73.9
WP_047425274.1\|1261583_1261784_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	9.0e-12	57.8
WP_054190169.1\|1262502_1262613_+	hypothetical protein	NA	NA	NA	NA
WP_054190168.1\|1263040_1263226_+	XRE family transcriptional regulator	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	77.0
WP_054190167.1\|1263737_1264154_+	hypothetical protein	NA	NA	NA	NA
WP_100793806.1\|1264296_1264530_+	hypothetical protein	M9NS63	Staphylococcus_phage	4.6e-07	93.9
WP_054190165.1\|1264555_1264750_+	XRE family transcriptional regulator	M9NSU5	Staphylococcus_phage	3.9e-20	86.4
WP_054190164.1\|1265876_1266071_+	LSM domain protein	A0A1J0MG79	Staphylococcus_phage	8.2e-18	69.8

DBSCAN-SWA_7

1446480 : 1534948

106

Staphylococcus_phage(79.27%)

transposase,holin,terminase,plate,portal,integrase,tail,protease,tRNA,head,capsid

attL 1482782:1482810|attR 1529333:1529361

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858789.1\|1446480_1447773_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0
WP_054190669.1\|1448095_1450789_-	ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	1.2e-45	34.2
WP_054190668.1\|1450812_1451784_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_054190667.1\|1451770_1452973_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	7.1e-35	43.3
WP_054190666.1\|1452977_1454120_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_054190665.1\|1454375_1454693_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_001827022.1\|1455028_1455709_-	zinc metallopeptidase	NA	NA	NA	NA
WP_054190664.1\|1455780_1456368_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000005212.1\|1456357_1456933_-	YpiB family protein	G3MAV7	Bacillus_virus	2.1e-08	27.2
WP_054190663.1\|1456946_1458191_-	hypothetical protein	NA	NA	NA	NA
WP_054190662.1\|1458197_1459496_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_054190661.1\|1459505_1460570_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_054190660.1\|1460595_1461762_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.1
WP_054190390.1\|1462158_1463475_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	6.4e-45	33.1
WP_000442480.1\|1463727_1464177_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
WP_001096479.1\|1464269_1465229_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1465230_1465956_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450553.1\|1465958_1466531_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1466962_1467235_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_054190658.1\|1467405_1468404_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1468420_1469731_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_054190657.1\|1469952_1471128_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_054190655.1\|1471692_1471809_-	hypothetical protein	NA	NA	NA	NA
WP_054190654.1\|1471839_1472499_-	(d)CMP kinase	NA	NA	NA	NA
WP_054190653.1\|1472575_1473544_+	asparaginase	NA	NA	NA	NA
WP_054190652.1\|1473659_1474646_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_054190651.1\|1474806_1474923_-	hypothetical protein	NA	NA	NA	NA
WP_054190650.1\|1475048_1476509_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_054190649.1\|1476661_1478041_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	3.2e-55	33.3
WP_054190648.1\|1478030_1478984_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001151997.1\|1479091_1479340_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_054190647.1\|1479445_1479991_-	ECF transporter S component	NA	NA	NA	NA
WP_054191869.1\|1480637_1481552_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_054190756.1\|1481609_1482515_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000470336.1\|1482605_1482791_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
1482782:1482810	attL	NA	NA	NA	NA
WP_024937002.1\|1483039_1484023_-	Panton-Valentine bi-component leukocidin subunit F	A0A2I6PEU3	Staphylococcus_phage	4.0e-185	100.0
WP_000239545.1\|1484018_1484957_-	Panton-Valentine bi-component leukocidin subunit S	A0A2I6PER8	Staphylococcus_phage	3.7e-180	100.0
WP_000909220.1\|1485346_1486801_-	N-acetylmuramoyl-L-alanine amidase	A0A2I6PET7	Staphylococcus_phage	5.7e-289	100.0
WP_000339146.1\|1486811_1487114_-\|holin	phage holin	A0A2I6PET6	Staphylococcus_phage	7.0e-48	100.0
WP_000466784.1\|1487249_1487549_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000916020.1\|1487594_1487759_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1487751_1488141_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_054189545.1\|1488140_1489607_-\|plate	phage baseplate upper protein	A0A2I6PDE3	Staphylococcus_phage	8.4e-272	99.0
WP_000429558.1\|1489606_1491517_-	minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
WP_054189544.1\|1491532_1491823_-	hypothetical protein	U5U457	Staphylococcus_phage	7.9e-49	99.0
WP_000384462.1\|1491822_1493406_-\|tail	phage tail protein	Q8SDP1	Staphylococcus_virus	7.1e-309	100.0
WP_020444679.1\|1493414_1494239_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.2e-158	99.6
WP_054189543.1\|1494238_1500439_-\|tail	phage tail tape measure protein	M9QQM6	Staphylococcus_phage	0.0e+00	99.6
WP_000438833.1\|1500452_1500611_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589167.1\|1500652_1501003_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.1e-55	100.0
WP_000169127.1\|1501060_1501516_-	Ig domain-containing protein	A0A2I6PER6	Staphylococcus_phage	5.7e-78	100.0
WP_000807536.1\|1501607_1502249_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023806.1\|1502283_1502679_-	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
WP_000110023.1\|1502679_1503081_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
WP_000395498.1\|1503077_1503410_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000050973.1\|1503421_1503700_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142735.1\|1503768_1504932_-\|capsid	phage major capsid protein	A0A2I6PE62	Staphylococcus_phage	3.6e-217	100.0
WP_000061866.1\|1504943_1505717_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001100665.1\|1505700_1506939_-\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	1.2e-234	100.0
WP_050974185.1\|1506943_1508635_-\|terminase	terminase large subunit	Q4ZD20	Staphylococcus_virus	0.0e+00	99.8
WP_000778933.1\|1508624_1508930_-\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000160686.1\|1509056_1509371_-	HNH endonuclease	A0A2I6PEN4	Staphylococcus_phage	5.0e-57	100.0
WP_000528512.1\|1509527_1509965_-	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_001793488.1\|1509977_1511345_-	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	1.7e-263	100.0
WP_001548892.1\|1511325_1511616_-	VRR-NUC domain-containing protein	A0A2I6PE31	Staphylococcus_phage	6.5e-51	100.0
WP_001801650.1\|1511749_1511848_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	3.7e-11	100.0
WP_054189542.1\|1511956_1514404_-	virulence-associated E family protein	R4WAL1	Staphylococcus_phage	0.0e+00	99.3
WP_000265258.1\|1514455_1514656_-	DUF1514 family protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
WP_000237866.1\|1514723_1514876_-	transcriptional activator RinB	A0A2I6PF16	Staphylococcus_phage	5.8e-19	98.0
WP_001125015.1\|1514878_1515079_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195789.1\|1515053_1515242_-	DUF1381 domain-containing protein	A0A2I6PF34	Staphylococcus_phage	2.3e-25	100.0
WP_001209219.1\|1515258_1515432_-	hypothetical protein	S4SVD5	Staphylococcus_phage	3.6e-25	100.0
WP_054189541.1\|1515468_1515996_-	dUTP pyrophosphatase	A0A2I6PF13	Staphylococcus_phage	8.6e-94	99.4
WP_000700108.1\|1515988_1516231_-	hypothetical protein	A0A2I6PF40	Staphylococcus_phage	3.7e-36	100.0
WP_000370296.1\|1516220_1516457_-	DUF1024 family protein	A0A2I6PF11	Staphylococcus_phage	4.0e-35	100.0
WP_001813803.1\|1516449_1516617_-	hypothetical protein	A0A2I6PF20	Staphylococcus_phage	3.5e-25	100.0
WP_000178883.1\|1516628_1516877_-	hypothetical protein	A0A2I6PF06	Staphylococcus_phage	3.6e-42	100.0
WP_000235381.1\|1516885_1517086_-	hypothetical protein	A0A2I6PF32	Staphylococcus_phage	1.3e-29	100.0
WP_000111488.1\|1517088_1517346_-	DUF3310 domain-containing protein	A0A2I6PF10	Staphylococcus_phage	5.7e-43	100.0
WP_000113981.1\|1517345_1517747_-	PVL family protein	A0A2I6PF14	Staphylococcus_phage	1.2e-68	100.0
WP_001164629.1\|1517746_1517932_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_001796208.1\|1517944_1519897_-	DNA polymerase	A0A2I6PF18	Staphylococcus_phage	0.0e+00	100.0
WP_000645042.1\|1519965_1520523_-	DUF2815 family protein	A0A2I6PF05	Staphylococcus_phage	1.8e-97	100.0
WP_000762547.1\|1520548_1521715_-	DUF2800 domain-containing protein	A0A2D1G5B8	Staphylococcus_phage	8.3e-222	100.0
WP_000985984.1\|1521711_1522074_-	hypothetical protein	Q4ZCP8	Staphylococcus_virus	1.4e-55	99.2
WP_000175001.1\|1522088_1522412_-	hypothetical protein	A0A2I6PDL5	Staphylococcus_phage	1.7e-52	99.1
WP_001285954.1\|1522490_1522652_-	DUF1270 domain-containing protein	A7TWM3	Staphylococcus_phage	8.6e-21	100.0
WP_001124160.1\|1522664_1522928_-	helix-turn-helix domain-containing protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
WP_001097552.1\|1522952_1523168_-	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
WP_001128433.1\|1523222_1523588_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1523556_1523802_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_000642492.1\|1523857_1524067_+	hypothetical protein	W5R9J5	Staphylococcus_phage	1.2e-30	100.0
WP_000939498.1\|1524056_1524200_-	hypothetical protein	W5R8I6	Staphylococcus_phage	2.5e-16	100.0
WP_001148544.1\|1524228_1525005_-	Rha family transcriptional regulator	A0A2I6PD87	Staphylococcus_phage	1.1e-140	100.0
WP_001121027.1\|1525018_1525255_-	helix-turn-helix transcriptional regulator	A0A2I6PD81	Staphylococcus_phage	1.5e-37	100.0
WP_000333630.1\|1525406_1525721_+	helix-turn-helix transcriptional regulator	A0A0N9BAW4	Staphylococcus_phage	9.8e-53	100.0
WP_000525004.1\|1525733_1526195_+	hypothetical protein	A0A2K9VBR7	Staphylococcus_phage	1.2e-83	100.0
WP_000755718.1\|1526212_1526647_+	hypothetical protein	A0A2I6PEM0	Staphylococcus_phage	1.2e-24	100.0
WP_000449655.1\|1526675_1527071_+	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	3.8e-70	100.0
WP_001795334.1\|1527160_1527307_+	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	1.2e-16	100.0
WP_000191466.1\|1527303_1527918_-	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
WP_000264751.1\|1528043_1529249_+\|integrase	site-specific integrase	A0A2I6PEN0	Staphylococcus_phage	7.7e-223	100.0
WP_054189540.1\|1529291_1531319_-	hypothetical protein	B5WZK7	Staphylococcus_phage	1.6e-108	91.5
1529333:1529361	attR	NA	NA	NA	NA
WP_061745606.1\|1531330_1532239_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000987769.1\|1532490_1534242_-	two-component system sensor histidine kinase SrrB	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
WP_000064078.1\|1534222_1534948_-	two-component system response regulator SrrA	W8CYM9	Bacillus_phage	3.5e-45	43.0

DBSCAN-SWA_8

1590057 : 1598369

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054190032.1\|1590057_1590843_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-19	28.3
WP_054190033.1\|1590968_1591859_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062177.1\|1591868_1593215_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_054190034.1\|1593328_1594429_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	6.1e-09	30.6
WP_054190035.1\|1594431_1595109_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1595239_1596346_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_054190036.1\|1596569_1598369_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	6.0e-54	36.0

DBSCAN-SWA_9

1801095 : 1847771

Staphylococcus_phage(91.67%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054190151.1\|1801095_1807653_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	1.2e-208	66.5
WP_054190152.1\|1807977_1808289_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.5e-50	95.1
WP_100793818.1\|1808310_1810728_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.2
WP_054190154.1\|1811016_1812198_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.6e-217	99.2
WP_000526539.1\|1812307_1813261_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_054190156.1\|1813257_1813821_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	4.6e-101	97.3
WP_000757543.1\|1813942_1814344_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_061745617.1\|1815221_1816868_+\|transposase	IS1182 family transposase	A0ZS58	Staphylococcus_virus	3.3e-285	95.8
WP_054190561.1\|1816898_1817726_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|1817728_1817848_-	hypothetical protein	NA	NA	NA	NA
WP_054190562.1\|1817959_1818961_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.0e-184	99.4
WP_054190563.1\|1819082_1819547_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.3e-69	98.1
WP_054190564.1\|1819559_1820741_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.2e-225	99.0
WP_054190565.1\|1820751_1821384_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.1e-110	98.1
WP_054190566.1\|1821390_1822434_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	4.1e-196	98.8
WP_054190567.1\|1822914_1824417_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_054190568.1\|1825057_1825372_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	3.1e-51	96.2
WP_054190569.1\|1825371_1826664_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	6.3e-223	97.7
WP_054190570.1\|1826749_1827604_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1827873_1828098_-	hypothetical protein	NA	NA	NA	NA
WP_054190571.1\|1828296_1828767_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	9.7e-81	96.8
WP_054190572.1\|1828879_1829323_+	competence protein ComK	NA	NA	NA	NA
WP_054190573.1\|1829309_1829753_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	7.3e-54	84.4
WP_054190608.1\|1830050_1830686_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1831126_1831840_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_054190574.1\|1832099_1832402_+	hypothetical protein	NA	NA	NA	NA
WP_001200540.1\|1832656_1833022_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	4.8e-59	99.2
WP_054190575.1\|1833018_1833366_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	1.9e-20	87.9
WP_054190576.1\|1833615_1834449_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.3e-156	98.6
WP_000366165.1\|1834660_1835569_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
WP_000933822.1\|1835693_1836887_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_061745618.1\|1837258_1838851_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.6
WP_077446713.1\|1839331_1840078_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	5.1e-140	97.2
WP_077446708.1\|1840082_1840556_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.2e-83	98.7
WP_000718107.1\|1840621_1840879_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_054190580.1\|1840875_1841877_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.8e-180	95.2
WP_054190581.1\|1841881_1843360_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	4.3e-276	95.5
WP_077446714.1\|1843518_1843974_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-70	89.0
WP_078171169.1\|1844275_1844938_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	7.4e-18	60.0
WP_054193637.1\|1845018_1846014_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.4e-68	92.7
WP_054190584.1\|1846089_1846716_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	2.3e-77	87.6
WP_054190585.1\|1846756_1847098_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	7.8e-56	96.5
WP_054190586.1\|1847198_1847771_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.7e-24	93.1

DBSCAN-SWA_10

1860535 : 1879575

Staphylococcus_phage(93.75%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_054193639.1\|1860535_1861690_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.0e-38	36.5
WP_061745621.1\|1861682_1863239_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.4e-287	99.0
WP_054190775.1\|1863819_1864389_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	8.8e-36	49.5
WP_077446694.1\|1864866_1865565_-	BsaG protein	A0A2H4PQH0	Staphylococcus_phage	9.6e-109	91.4
WP_054190776.1\|1865561_1866323_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	1.1e-126	95.7
WP_054190777.1\|1866319_1867012_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	9.2e-120	97.0
WP_054190778.1\|1867034_1868408_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	3.8e-242	93.7
WP_054190779.1\|1868417_1868936_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	3.6e-92	95.3
WP_054190780.1\|1868951_1870196_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	1.2e-207	86.7
WP_054191893.1\|1870188_1873182_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	90.2
WP_000432510.1\|1873246_1873390_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	3.8e-20	100.0
WP_054190782.1\|1874363_1874882_+	PH domain-containing protein	A0A0D4DCT6	Staphylococcus_phage	9.1e-64	74.4
WP_054190783.1\|1875505_1876489_-	leukocidin/hemolysin toxin family protein	A0A2H4PQH7	Staphylococcus_phage	2.2e-175	93.3
WP_054190784.1\|1876489_1877425_-	beta-channel forming cytolysin	A0A2H4PQI5	Staphylococcus_phage	9.4e-152	85.3
WP_077446693.1\|1878216_1878774_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	1.2e-61	76.8
WP_054190786.1\|1878786_1879575_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	3.8e-138	94.3

DBSCAN-SWA_11

1908154 : 1979562

Staphylococcus_phage(72.31%)

holin,terminase,plate,portal,integrase,tail,tRNA,head,capsid

attL 1969923:1969938|attR 1984263:1984278

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181394.1\|1908154_1908625_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_054189549.1\|1908629_1909757_-\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_054189583.1\|1909907_1910630_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-37	42.7
WP_054189548.1\|1910622_1912080_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_054189547.1\|1912338_1913400_-	PTS transporter subunit IIC	NA	NA	NA	NA
WP_000110011.1\|1922223_1922670_-	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
WP_054189650.1\|1922766_1923717_-	hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_054189649.1\|1923722_1924178_-	peroxiredoxin	NA	NA	NA	NA
WP_054189648.1\|1924258_1925548_+	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_001236371.1\|1925840_1926935_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_054189647.1\|1927125_1928862_-	SAV1866 family putative multidrug efflux ABC transporter	W8CYL7	Bacillus_phage	1.7e-53	30.4
WP_000251253.1\|1929152_1929695_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_054189646.1\|1929997_1931035_-	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_054189645.1\|1931186_1932164_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_054189643.1\|1932424_1933261_-	hypothetical protein	NA	NA	NA	NA
WP_054189642.1\|1933269_1934787_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000435806.1\|1934801_1935116_-	YfhH family protein	NA	NA	NA	NA
WP_054189641.1\|1935093_1935912_-	recombination regulator RecX	NA	NA	NA	NA
WP_054189640.1\|1936172_1936982_-	monofunctional peptidoglycan glycosyltransferase SgtB	NA	NA	NA	NA
WP_054189639.1\|1937321_1937837_-	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_001005407.1\|1937966_1938128_-	hypothetical protein	NA	NA	NA	NA
WP_100250272.1\|1938474_1938555_+	hypothetical protein	NA	NA	NA	NA
WP_061745622.1\|1939200_1940646_-	SH3 domain-containing protein	Q4ZB16	Staphylococcus_virus	1.2e-294	99.4
WP_061745623.1\|1940626_1941064_-\|holin	phage holin	A0A2H4PQP0	Staphylococcus_phage	2.0e-72	99.3
WP_000398857.1\|1941119_1941515_-	hypothetical protein	A9CRD5	Staphylococcus_phage	6.1e-68	99.2
WP_061745624.1\|1941519_1942758_-\|plate	BppU family phage baseplate upper protein	A0A0F6N3G7	Staphylococcus_phage	1.7e-209	99.5
WP_061745625.1\|1942770_1944669_-	glucosaminidase domain-containing protein	A0EX80	Staphylococcus_virus	0.0e+00	98.1
WP_000466778.1\|1944805_1945105_-	DUF2951 domain-containing protein	A0A0H4ITZ0	Staphylococcus_phage	7.6e-47	100.0
WP_000782200.1\|1945144_1945318_-	XkdX family protein	A0A0F6N3L7	Staphylococcus_phage	6.6e-27	100.0
WP_000705896.1\|1945321_1945699_-	DUF2977 domain-containing protein	A0A0F6N3G4	Staphylococcus_phage	1.5e-60	100.0
WP_000634521.1\|1945698_1947522_-\|plate	phage baseplate upper protein	A0A0F6N3G2	Staphylococcus_phage	0.0e+00	100.0
WP_061745626.1\|1947521_1949432_-	hypothetical protein	A0A0F6N4K2	Staphylococcus_phage	0.0e+00	99.8
WP_061745627.1\|1949446_1951345_-\|tail	phage tail protein	A0A0F6N3M1	Staphylococcus_phage	0.0e+00	99.8
WP_000350675.1\|1951353_1952301_-\|tail	phage tail family protein	A0A0F6N3L4	Staphylococcus_phage	2.8e-183	100.0
WP_061745628.1\|1952313_1955778_-	hypothetical protein	Q4ZDE1	Staphylococcus_virus	7.3e-266	95.2
WP_000105584.1\|1955794_1956139_-	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
WP_001100163.1\|1956168_1956534_-	hypothetical protein	Q8SDT9	Staphylococcus_phage	2.8e-59	100.0
WP_000002576.1\|1956595_1957177_-\|tail	phage major tail protein, TP901-1 family	Q8SDU0	Staphylococcus_phage	2.4e-105	99.0
WP_000188643.1\|1957195_1957579_-	hypothetical protein	E0Y3L5	Staphylococcus_virus	3.8e-67	98.4
WP_001017815.1\|1957590_1957938_-	HK97 gp10 family phage protein	A0A0F6N3F5	Staphylococcus_phage	4.1e-60	100.0
WP_001268312.1\|1957937_1958240_-	hypothetical protein	A4ZFB6	Staphylococcus_virus	1.1e-50	100.0
WP_000208960.1\|1958236_1958569_-\|head,tail	phage head-tail connector protein	A0A0F6N3F4	Staphylococcus_phage	5.5e-54	100.0
WP_001114086.1\|1958577_1958865_-	hypothetical protein	S4V6D9	Staphylococcus_phage	1.4e-45	98.9
WP_000438503.1\|1958886_1959861_-\|capsid	phage major capsid protein	E0Y3L0	Staphylococcus_virus	6.3e-183	99.4
WP_000354305.1\|1959874_1960489_-	DUF4355 domain-containing protein	I1W646	Staphylococcus_phage	2.9e-40	100.0
WP_001824752.1\|1960620_1960794_-	hypothetical protein	NA	NA	NA	NA
WP_025380771.1\|1960875_1961871_-\|capsid	minor capsid protein	E0Y3K7	Staphylococcus_virus	1.3e-180	97.3
WP_061745629.1\|1961877_1963413_-\|portal	phage portal protein	A1KX25	Staphylococcus_virus	6.5e-291	99.8
WP_061745630.1\|1963423_1964701_-\|terminase	PBSX family phage terminase large subunit	Q8SDU9	Staphylococcus_phage	1.5e-248	99.8
WP_061745631.1\|1964687_1965128_-\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.1e-73	98.6
WP_000058632.1\|1965314_1965734_-	transcriptional regulator	I1W651	Staphylococcus_phage	8.1e-71	100.0
WP_000990007.1\|1965748_1965895_-	hypothetical protein	Q4ZDN7	Staphylococcus_virus	2.3e-12	81.2
WP_025174872.1\|1965895_1966069_-	transcriptional regulator	A1KX88	Staphylococcus_virus	8.3e-22	96.5
WP_001125015.1\|1966071_1966272_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195817.1\|1966246_1966435_-	DUF1381 domain-containing protein	A0A2H4PQK3	Staphylococcus_phage	1.8e-25	100.0
WP_001209216.1\|1966451_1966625_-	hypothetical protein	A0A1W6JQ45	Staphylococcus_phage	4.7e-25	100.0
WP_015984502.1\|1966661_1967195_-	dUTP nucleotidohydrolase	A1KX16	Staphylococcus_virus	1.1e-96	100.0
WP_000714412.1\|1967187_1967358_-	hypothetical protein	A7TWH6	Staphylococcus_phage	1.5e-20	91.1
WP_001661914.1\|1967344_1967599_-	DUF1024 family protein	A1KX15	Staphylococcus_virus	5.5e-38	96.4
WP_001622142.1\|1967613_1967862_-	hypothetical protein	A0A1W6JPX8	Staphylococcus_phage	2.1e-42	97.6
WP_001622141.1\|1967862_1968222_-	hypothetical protein	B2ZYW3	Staphylococcus_phage	3.2e-60	97.5
WP_020808085.1\|1968222_1968411_-	DUF3113 family protein	A0A0E3TAK3	Staphylococcus_phage	2.0e-24	96.7
WP_000049795.1\|1968415_1968820_-	DUF1064 domain-containing protein	A0A068A2B2	Staphylococcus_phage	9.6e-69	100.0
WP_001123695.1\|1968829_1969051_-	DUF3269 family protein	A0A0H3U2V4	Staphylococcus_phage	2.2e-35	100.0
WP_000256589.1\|1969063_1969222_-	hypothetical protein	A0A2H4PQI7	Staphylococcus_phage	4.5e-22	100.0
WP_000803062.1\|1969215_1969995_-	ATP-binding protein	G4KNP1	Staphylococcus_phage	3.8e-146	100.0
1969923:1969938	attL	NA	NA	NA	NA
WP_000190254.1\|1970004_1970775_-	conserved phage C-terminal domain-containing protein	G4KNP0	Staphylococcus_phage	6.4e-122	100.0
WP_000414755.1\|1970840_1971122_+	hypothetical protein	A0A1W6JPU7	Staphylococcus_phage	2.6e-49	100.0
WP_001081076.1\|1971114_1971264_-	hypothetical protein	A7TWN0	Staphylococcus_phage	2.4e-17	100.0
WP_001124438.1\|1971260_1971935_-	hypothetical protein	R4IH15	Staphylococcus_phage	1.4e-125	96.9
WP_000934385.1\|1971948_1972377_-	single-stranded DNA-binding protein	B2ZYV4	Staphylococcus_phage	3.9e-60	100.0
WP_000139720.1\|1972376_1973000_-	DUF1071 domain-containing protein	A0A2H4PQQ6	Staphylococcus_phage	1.4e-114	100.0
WP_000815402.1\|1972992_1973214_-	DUF2483 family protein	B2ZYV2	Staphylococcus_phage	3.2e-34	100.0
WP_000291089.1\|1973223_1973484_-	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	1.2e-43	100.0
WP_000048126.1\|1973575_1973737_-	DUF1270 family protein	A0A2H4PQQ1	Staphylococcus_phage	3.3e-20	100.0
WP_000977380.1\|1973729_1973951_-	hypothetical protein	A0A0F6N3I2	Staphylococcus_phage	9.6e-31	97.3
WP_000388992.1\|1974021_1974579_+	hypothetical protein	A0A2H4IYS4	uncultured_Caudovirales_phage	1.7e-47	54.5
WP_000939503.1\|1974599_1974743_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.8e-14	91.3
WP_001148854.1\|1974773_1974968_-	hypothetical protein	Q4ZDS1	Staphylococcus_virus	4.6e-21	90.5
WP_061745632.1\|1974984_1975770_-	phage antirepressor KilAC domain-containing protein	R4IFK0	Staphylococcus_phage	4.1e-132	91.6
WP_044122308.1\|1975769_1975964_-	helix-turn-helix transcriptional regulator	A0A0F6N3M9	Staphylococcus_phage	7.2e-22	87.5
WP_061745633.1\|1976241_1976580_+	helix-turn-helix transcriptional regulator	R4IH08	Staphylococcus_phage	1.6e-29	59.1
WP_061745634.1\|1976592_1977264_+	ImmA/IrrE family metallo-endopeptidase	A0A0F6N3H6	Staphylococcus_phage	2.2e-46	46.1
WP_000392183.1\|1977311_1978244_+	hypothetical protein	A0EX19	Staphylococcus_virus	6.7e-174	100.0
WP_000337827.1\|1978223_1978403_-	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
WP_001145722.1\|1978515_1979562_+\|integrase	site-specific integrase	Q4ZB10	Staphylococcus_virus	5.5e-201	100.0
1984263:1984278	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LN854556

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection