CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT827010	Actinoplanes sp. SE50/110 isolate ACP50 chromosome I	25 crisprs	csa3,cas3,DEDDh,WYL,Cas9_archaeal,DinG	4	7	4	0

1. NZ_LT827010

CRISPR-Cas detection and classification

Crispr_ID: NZ_LT827010_1

• CRISPR_ID: NZ_LT827010_1
• CRISPR_location: 316920-317001
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_1

Consensus_repeat	Method
CACGCCGCGGTTCGTCTCCTCCAGCTCG	CRISPRCasFinder

spacers of NZ_LT827010_1

>1.1|316948|26|NZ_LT827010|CRISPRCasFinder
TCGGAGAGCTGGTGGTAGAGCGCCAT

CRISPR arrays and Neighbor proteins around NZ_LT827010_1

CRISPR arrays

The CRISPR arrays of NZ_LT827010_1

>merge|NZ_LT827010|1|316920-317001|CRISPRCasFinder
CACGCCGCGGTTCGTCTCCTCCAGCTCGTCGGAGAGCTGGTGGTAGAGCGCCATCACGCCGCGGTTCGTCTCCTCCAGCTCG

>NZ_LT827010|1|1|316920-317001|CRISPRCasFinder
CACGCCGCGGTTCGTCTCCTCCAGCTCG	TCGGAGAGCTGGTGGTAGAGCGCCAT
CACGCCGCGGTTCGTCTCCTCCAGCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014687351.1|307843_308530_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_LT827010.1|WP_014687358.1|318555_318960_-|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|340411
NZ_LT827010.1|WP_014687363.1|321446_321677_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014687348.1|303456_305454_-|threonine--tRNA-ligase	unknown	unknown	gnl|CDD|237050
NZ_LT827010.1|WP_014687353.1|309163_311455_+|hypothetical-protein	unknown	unknown	gnl|CDD|379396
NZ_LT827010.1|WP_063713987.1|305625_306315_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043510641.1|300748_301981_-|MFS-transporter	unknown	unknown	gnl|CDD|340887
NZ_LT827010.1|WP_014687352.1|308526_309063_-|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_LT827010.1|WP_014687354.1|311517_314604_+|VCBS-repeat-containing-protein	unknown	unknown	gnl|CDD|379232
NZ_LT827010.1|WP_014687355.1|314610_316185_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_LT827010.1|WP_014687350.1|306344_307847_-|FtsX-like-permease-family-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014687361.1|320410_320764_+|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_LT827010.1|WP_043513331.1|317527_318559_-|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|340411
NZ_LT827010.1|WP_014687365.1|322594_323218_-|CGNR-zinc-finger-domain-containing-protein	unknown	unknown	gnl|CDD|378696
NZ_LT827010.1|WP_043510650.1|321755_322544_-|zf-HC2-domain-containing-protein	unknown	unknown	gnl|CDD|227947
NZ_LT827010.1|WP_014687360.1|319383_320244_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NZ_LT827010.1|WP_043513332.1|320873_321341_+|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl|CDD|376605
NZ_LT827010.1|WP_172898842.1|323374_324142_+|murein-L,D-transpeptidase	unknown	unknown	gnl|CDD|341130
NZ_LT827010.1|WP_014687359.1|318956_319382_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132912
NZ_LT827010.1|WP_014687347.1|301980_303174_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014687351.1|307843_308530_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.45664e-93
NZ_LT827010.1|WP_014687358.1|318555_318960_-|anti-sigma-regulatory-factor	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	3.03809e-41
NZ_LT827010.1|WP_014687348.1|303456_305454_-|threonine--tRNA-ligase	gnl|CDD|237050	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed.	0
NZ_LT827010.1|WP_014687353.1|309163_311455_+|hypothetical-protein	gnl|CDD|379396	pfam13861, FLgD_tudor, FlgD Tudor-like domain. This domain has a tudor domain-like beta barrel fold. It is found in the FlgD protein the flagellar hook capping protein. The structure for this domain shows that it contains a nested Ig-like domain within it. However in some firmicute proteins this inserted domain is absent such as Q67K21.	5.29175e-09
NZ_LT827010.1|WP_014687359.1|318956_319382_-|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	1.37428e-31
NZ_LT827010.1|WP_043510641.1|300748_301981_-|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.59361e-24
NZ_LT827010.1|WP_014687352.1|308526_309063_-|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.65362e-16
NZ_LT827010.1|WP_014687354.1|311517_314604_+|VCBS-repeat-containing-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	8.68424e-09
NZ_LT827010.1|WP_014687355.1|314610_316185_-|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.3768e-44
NZ_LT827010.1|WP_014687361.1|320410_320764_+|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	5.34717e-29
NZ_LT827010.1|WP_043513331.1|317527_318559_-|SpoIIE-family-protein-phosphatase	gnl|CDD|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	7.11962e-28
NZ_LT827010.1|WP_014687365.1|322594_323218_-|CGNR-zinc-finger-domain-containing-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	5.70791e-14
NZ_LT827010.1|WP_043510650.1|321755_322544_-|zf-HC2-domain-containing-protein	gnl|CDD|227947	COG5660, COG5660, Predicted integral membrane protein [Function unknown].	3.01072e-18
NZ_LT827010.1|WP_014687360.1|319383_320244_-|STAS-domain-containing-protein	gnl|CDD|132912	cd07041, STAS_RsbR_RsbS_like, Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation. The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.	2.80927e-43
NZ_LT827010.1|WP_043513332.1|320873_321341_+|large-conductance-mechanosensitive-channel-protein-MscL	gnl|CDD|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	7.41541e-49
NZ_LT827010.1|WP_172898842.1|323374_324142_+|murein-L,D-transpeptidase	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	5.29763e-16

Protein sequences

>NZ_LT827010.1|WP_014687355.1|314610_316185_-|SpoIIE-family-protein-phosphatase
MTELARVERLVQGHVKATVLVVDDSATKRYLLVSWLTRAGFTVIEAETGGEALRKLGEDLVEADLVVLDVKLPDMSGFEVCERIKTDQRYGVLPVIHVSAHAVDVNDRTQGLNRGADAYLVEPIEPDELIATVQAVLRYYRARQRAELLAARLVRLAETTLAINSASTLPALLEAAAVGAADIFGGPVVVVAETSEGESLAAAGPPLGVRKWAVPHHRVAVGSLVRTDEPADWDVVDWPAGESVAVAAARLRIDRPPVYLAVSGSTQTPGFPVLRQLSQAVAAAVEAQRSFDEEHRIAVTLQRSLLQSTLPRVPGVEMAVRYEPAGAQTEVGGDFYELTVLDGKLLVAIGDVAGHSLHAATVMAEVRHAVRAYAVEGHSPGAVLGLTNRFMRTVLPADSATLCLFTLDPATGRIRMASAGHLPPLLHVDGEVRFLSPRGALLGLDAPERTELELELPPGGTLVLYTDGLIERRDADIDEGLRALAACAADVEPDLDAFCSRLLTRLGGSGDQADDIAVVALRRA
>NZ_LT827010.1|WP_014687354.1|311517_314604_+|VCBS-repeat-containing-protein
MSTAARRGLAAAGCIALSAAGLTALPVTPAHATVALPQPSEVSVVPAYPTRTDFPVDSLVLAGETGFLHQYGGSSWATSTWLWTRYADGSTRVVTELAGLTAPALAWAGGDRIWVKTDVAGHSDDRSLTIFDAAAGTWSNPTLPTDGTKLAYSAGTMLVRLGTAGPLELRKFAADGTYTTIPITGVPDGTAVSGGSGTVFDSTTFLVSFSGTTDGVKWQRLGLLDFTSGKVSLLPQFTFGTVNQILLSATHLGFRGGNTVRVFSRAAITAGTATDPAVITVPSVPYLTLVGGDMLVRASAADNRAPARLISADGSERTVLPMSQSNPYAMATAPGGALLVGGSGAADWAVQRITADGVQPVMSEVRTNFSAGITISRGQLRHVRAGARPFESPVYDFSNHELIPGLTGLPVTGPTMTGVTSCAADVTCVRTMDGNRYGTGWTSSTETTTTVRFADGASGGFSLVLAGGGGSLVDVSDDYAIVNTTSPAKQYVIPTANPDARTERAVTAAALDYATLWTAGAGQIRSKDLTTGKTAAPISIGAACTPSELQAAGRFVFWSCGVAGPAGVYDVPQRINHPLPAGRYLLGDGYAVRHDAATGRLISYDVTLRGAPKTAILGTLDRGTPADDRNITWAVDKYSGNVAYVDAAGAAHVIDPAVVERPPTVIRSTTSADVVYHDHDRPWVRQYTLSRPVASWRAEIAELHSGKVVMTLNGGASTGEVRLAWDGYLADKTPAPAGRYRVNLVVTTPDGVGHDIAGSPVYLDGERPRLHSYGLDGMPSMLSVDPQGNGAWWHAYADRRSLVYQYISEFWDLGTGNSQISALVPYGDINGDRNNDVLARTGNGVLWAHLGFGEDYFGSDRNRVVKIGTGWNRFDTLITTGDVTGDGITDLLARDARTGKVLRYAGNGTGGFTNGVPLSGSYQGFRLIGPGDVDGDGHADLLLIDGRGGLYAQYGTGTGTFGASTRIGSGFKAYNVVLGIGDLNLDGLNDLLARDASGKLYRFLGTDAGTFGAAERIGSGYQTYAGLF
>NZ_LT827010.1|WP_014687353.1|309163_311455_+|hypothetical-protein
MPMTRRGLAATCCSLLALTGISVAAPASATVPLSNPHEVATIPADPPFEYREDHVAFAGRTGYLHSRANGGGTWQWTTYADHTTTTVTTLGRLYPGDFVSAGGDTVYVDADVDGHSEADTVSTLDLGTMTWQHRPRTADFRAVYGDTWYVRSSSATPALRHFAVDGSSIDVPMTGIPAGTASILAVRGDSTGMVIRFGGKPNTFGWQFGLLDLASGKVSPFGGNRATVASSVLLSAGRVALLDEGADTGTAEIFDRAAVLNGTAPASPEPIHLPLTQQYRLALAGNDVLASPEPRGGGVAPAVYRYSADGSHRTLFAQSQPGSGSLTQAEDGAVVVGGADSGDWGIHRITAAGDTRLADLSAKAGTTGVTISQGMVRRVQTVTWAGDQYTFLHLINHHLSEGIDRQVPVDGGRVGAFLCQPAAFCIRTVDGNRYGTSFAAGYSVLTMDSVARPSVDTDISGLTVNDAAVVDAGLEYVVSDFPRANVQVILRAGAGDTDVVQRPITGAALWFNTLWTGLPGKIQPTNVTTRVSSPAIPIGAACTPSELQATDRYVYWSCGTAGPAGVYDGVTKTSRQVPPAQYLLGDGYLVRHDAATGKLIRIDLRLRGTLGRSATLGTIPRGTLADDRNITWAVDKYSGDVAYVDAANTIHVIDTGVARSAPAVVGRPAGNLNPAAGQSSSWSFTLNRPVDVWTATITQNGVVVRTLTGGPADRTAQVTWDGLRADGRPAAAGRYQLTFAAVAGGVSGTPSTATVNVSAAASR
>NZ_LT827010.1|WP_014687352.1|308526_309063_-|PadR-family-transcriptional-regulator
MSTAHVLLGLLADGPRHGYELKRAHDDRLPLAKPLAFGQVYATLGRLERDGLVVRSGQDQESGPERTSFELTSLGRDRLAAWLTEVEPPAPHVTSTLFSKVVVALLAAGADRARDYLVAQRAAHMARMRELTSTKTMPGASVGDIVAADYAIGHLDADLRWLQTTLARVADLHKEVTA
>NZ_LT827010.1|WP_014687351.1|307843_308530_-|ABC-transporter-ATP-binding-protein
MSTPLLTGTGIVKSYGATPALRGVDVTVGAGEIVAITGPSGCGKSTLLHCLAGIIRPDAGSVVYRDQDLTLWSEASRSRLRRTEFGVLFQFGQLVPELTAAENVALPLLLAGSGRREARGAALGWLDRFGVAEVADKRPGAMSGGQQQRCAAARALVTEPAVIFADEPTGALDQLSGEQVMAAMVQVVREQGSAVVLVTHEAPIAAYADREIVLRDGAVDASGIGIFG
>NZ_LT827010.1|WP_014687350.1|306344_307847_-|FtsX-like-permease-family-protein
MRAGTLVRLSLAGNRTDRLRTALTAGSGALAALALLAAATVAAIHGGEWVYDPADPARRSNLSPGSSQYSSALLAEHGLRPGVIFALVMLALPVLALAGQCIRLGAPARDRRLAALRLAGATPGETALVAGAETAAAGLLGSLAGYGLFLLLRVLLNRRTADGKLLLPTDVLPGPVATVLVLLLVPVLSGLIGTLLMRRVVVTPLGVVRQIRDDGPRPWPGVLIAVGLVLFAPRTLHLIPPGWHVPDWTPLVMMGASVLLVVIGVVLGTGWISYTTGRLLRRFGRGPVTLLAGARLMADPWNGSRTLGALLAAVVFGAGTLGYRADLAADFAARERFDQLTDPQYGRYGPAFDTGFYFGAIRLILVAVVLALVVASAGILVTFAEGITARRRTFAAMTAGGVPRGKLGAMLFWHTFAPLLPALLLALTAGVSLIRTMRTEVDVSEPGPAGDLAVVHMPIPLPLAQLTLLGAATLATMLLVTGAGLLVLRAGTDLEELRAG
>NZ_LT827010.1|WP_063713987.1|305625_306315_-|hypothetical-protein
MRLLTAAVVIGLGVRVVRSRHRRFLHPAGRSFAGTLEIWGGAEPLGATLLDTPAVHDVTVRVSKGAGTRGARVDIRGVAVRVGPADLLLSSTGRTALTKRLPVPRLSFDTVYGAITPYRTGTRKLYLEAVPDPDARPLGRALSSIPAGAALLLRADDRTVGRVALRHALPEATDAALAFDPIRNATPDLHPTGLIHGSRALAYRLSQRWRGATPPATDPAALARTVTHH
>NZ_LT827010.1|WP_014687348.1|303456_305454_-|threonine--tRNA-ligase
MSAPLTPVVADPVVVPAGTTAADAVSAAGLPSSGPKAIVVVREADGRLRDLAWIPEADAEVTPVAMDEPDGLNVLRHSAAHVLAQAVQEVFPEAKLGIGPPIRDGFYYDFDVEKPFQPDDLAKLEKRMQEIVKAGQTFHRREYASLDEAKAELAAEPFKLELVDIKGEVDPEAAAVGAGELTHYDNLDRDGKRVWGDLCRGPHLPSTRLIPAFKLMRSAAAYWRGSEKNPQLQRIYGTAWPSRDELKAYLHRLAEAERRDHRKLGTELDLFSFPDEIGSGLPVFHPKGGVIKREMEDYVRARHIEEGFQYVGTPHITKEGLFHTSGHLPYYKDTMFPPLQMEGADYYLKAMNCPMHNLIFKSRGRSYRELPLRLFEFGSVYRYEKSGVVHGLTRVRGFAQDDSHSYVTAEGAADEVRHLLNFVLSLLRDFGMDDFYLELSTRDPKSDKFIGSDEQWAVATKVLEDVCIESGLDLVPDPGGAAFYGPKVSVQVKDAIGRTWQMSTIQYDFSQPAGFGLEYQAADGSRQEPVMIHSAKFGSIERFFGVLTEHYAGAFPAWLAPVQVVGIPIRDDHADYLSSFVERLRREGIRAEVDYSSDRMQKKIRTAQQQKIPFMAIAGDDDVNGGTVSFRYRDGSQRNGVTLDEAVAHVAEVVRSRVNTGPSAA
>NZ_LT827010.1|WP_014687347.1|301980_303174_-|hypothetical-protein
MNLPYARVPGNPPFAAARVLDVAALRDMWLPWISMEAAPTTHVVARNSYLTWTYVCRTDSADIFARPWLSMYASGGLRAFVLDQARAVDHLQQEESCPAEMKELRDTWLGWLHGDDVLRRLQATALLGTLTTTLPLIGTDDPDPAVADPVHQHWCYERAKAIRARDLGHAPSAATMEYLAESAIEPAIRMLALVHLITYGIRFGMESDRVGGWVEQAGAVVPALAEHPHWLGLTVENRLQRVLALRYARQNDDAAVRRTLARAVELDRALAAYADDSILLRSLSTEIHRLLLDVQVRYETKCGTLATAAPMIAELDRIEPHYPDSRSAIGALYAANDLPDRAAAQFEQAAAGGSVLGAIAAFRAFECHRLAGDRDGAERSLLLLADLDPAADIGRYT
>NZ_LT827010.1|WP_043510641.1|300748_301981_-|MFS-transporter
MTVLTSWWRANLPADPAGRRFVAGSLVDNLGSGVRDVILPLFLVQIAGLPVAEVGTGLLVSGLIGLLGAPFAGRAADRAGAKTALTLGCTLNAVVSCLLISIHSLAAMCLLLAVSRVATQFSRVGRLTILAHVAGERRNTLRAQINIFNNVGVAVGMGVSATALTLGTRSAYLAGFLLDAVTFLIAVAIQLPIRVDAIAGPAVTPPRAPAPWRHLFTDHRYAVATALNGLLCLHQAILFLGIPLWIAATHLVPRPVTAVLFLLNLTLVIALQVRFSAPVRGLAPAARSWRRSATGVAGACALMVAATRVDSTAVRVALVVGAGALLTLGELCYSAAETEISTVLAPAEHRGLYQGVFVLGRDAAQTAGPLVAALFCVSLHAWGWGLLLAGFALFAVLAPAAVRHPEPVSV
>NZ_LT827010.1|WP_043513331.1|317527_318559_-|SpoIIE-family-protein-phosphatase
MTGGTVALVPEGLLDEGVWFRVEAAGTAAAVRRAAERLAAELAMPERRIADLSIVAAEMAGNLVKHAHQGTILVRTVRTAEQAGVELIAIDSGPGMSDVPHAFGDGHSTAGTLGIGLGAIQRQAGRWDLHSVPGRGTVLAVQVWPGVTPPPAWASGLTRPITGETVSGDAVAIREMDGRRQMLVCDGLGHGGLAAAASREAVRVFRETPATSPAAIVEALHRAMGHTRGAALAVADLDPATRQARYAGLGNIAGTIFSFEGTRRGMISMPGIAGHQRRQIREYEYPLPPDGFVLMHSDGVVDRWNPTDYPGLLTRSPELIAATVLRDAGTRRDDAGVLVARLP
>NZ_LT827010.1|WP_014687358.1|318555_318960_-|anti-sigma-regulatory-factor
MNEESRRIPVTTDQDVVRVRQLVRTVSVEAKLSLVDQTKLVTAASELARNTLVYGGGGEVEVSRVRNDLRAGIRIVFSDQGPGIADLDLALTDGYTTGGGLGLGLSGARRLVDEFSIETAVGEGTTITVTKWCR
>NZ_LT827010.1|WP_014687359.1|318956_319382_-|STAS-domain-containing-protein
MERVPVLKIGDILLVSIQIDMEDQTALQLQEDLAERIVATGCHGVIIDISALDIVDSFVGRTLATIASVSRVLDAETVVVGMRPAVAITLVELGLSLPGIRTALNVELAIEMLAQSRAVTMGEFDDDEDEDEADQTAVTAP
>NZ_LT827010.1|WP_014687360.1|319383_320244_-|STAS-domain-containing-protein
MALSPDESGRFADLLKEHADGLVARWAVLVGVSLQGRMSRPELERQTRDLHKGFQQALAAGAQDLGDEAAGELRAQLSELSSSRARQGFSATETAVSVFALKDAVLEVLGDAGDDAHTLRGYVAFSAFVDRAALFTFDAYVRVRESLIADQAEQLLELSTPVVKLWEGVVAVPLVGTLDSARAQVVMERLLQTLVDTGSPYAIIDITGVPAVDTQVAQHILKTVVAARLMGADCIISGIRPQIAQTIVALGIEFGDIATKSSLADALRYVLGRNSYKVVTAKRTER
>NZ_LT827010.1|WP_014687361.1|320410_320764_+|STAS-domain-containing-protein
MSLTVQTEQRGDMVVVSVAGELDMATAPQLQDQISDLLEKGRTRLVFDLAEVSFCDSTGLSVFVRAKNSTDDAGGTVRLAAPQRGVLRILEVSGLVEVLHTYPTVDEAVTAEEPALD
>NZ_LT827010.1|WP_043513332.1|320873_321341_+|large-conductance-mechanosensitive-channel-protein-MscL
MFQGFKDFIMRGNVVDLAVGVVIGSAFTAVVTSLTNGFLKPLIQVISGGNGMDAGSFKIRGVKFDYATFINSAITFLLTAAVLYFLVVYPLNVLAERRRRGEEPPPKSPSEEVKLLTEIRDALVAQAAAGRGNTQGQVYGSAVDEVLQRRQDPPR
>NZ_LT827010.1|WP_014687363.1|321446_321677_+|hypothetical-protein
MEQRKHWWNGKWGRLARKDVYLRTNGDQWYVEQRAGGSDGTSHFFEYDSEDAALDMVRALLNGPDEWRELSVRPPR
>NZ_LT827010.1|WP_043510650.1|321755_322544_-|zf-HC2-domain-containing-protein
MACERWREMLSAQLDGEDDPALRPLVDEHVSGCAGCRAWLDAAAAVNRMTSTGRMPDVPDLSASILAALPPSAPARPAPARWWRRLPVAALLYVSLALVGAVQIILGLAQIGGDSAAGHVHLGLSATPGHLWNESAAWNAAIGAGYLFIALRRTRPVGLVPMLTAFVAMLLLLSLNDLTGGRVDVARLVGHGFVIVGYLLVVVLSRGAGDTARPPGARAGAGWRLTGAAEDEPGIAAPHRPGLRLVPPTGPLTAHHDDQQAA
>NZ_LT827010.1|WP_014687365.1|322594_323218_-|CGNR-zinc-finger-domain-containing-protein
MSWKASARHGVREAPGGFALIQELLNTRAAMSYGPDLLGVVEDAQWWVTDALGTWSRTSGLPAPTLLLSATDLRSLRRLRSAFEQVVLAGANQEPPGALPPADVPVSLAPDAAGWVRVVPTGRGTRWLASALWAEALLAQQAGLWPRLKLCHNTVCRAAFFDTSRNNSGVWHDVSTCGNTANLRAFRERRRLLGHSEELQVDDHHHR
>NZ_LT827010.1|WP_172898842.1|323374_324142_+|murein-L,D-transpeptidase
MAGCDSGRGTGPTGAQGTAGVPGTATGVPPRQSTAPSASAEPSASVVPGPSVSAPAAPRKLKVGAKGGDVLAVQRRLTELGYWNGGADGTFGDSTQQAVYALQKAAGIGRDGTVGPKTLKALDAGVRPAARSTKGRVVEIDLNRQLLLLVDGGRITQIFNTSTGSNRYYEQKGGRFLADTPRGRFTVGREIDGWRNAPLGLLWRPKYFNGGIAVHGANSVPPYAASHGCARVSIAAMNWMWNNDALPLKTKVWVY

Crispr_ID: NZ_LT827010_2

• CRISPR_ID: NZ_LT827010_2
• CRISPR_location: 701372-701478
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_2

Consensus_repeat	Method
GGGGCAGCGTGGGTGGCTGGCGTGGTC	CRISPRCasFinder

spacers of NZ_LT827010_2

>2.1|701399|53|NZ_LT827010|CRISPRCasFinder
GTGGGGGAGGGGCGGCGCGATGGCGGGACGCGTCGCGCGGTGGTGTCGGCAGT

CRISPR arrays and Neighbor proteins around NZ_LT827010_2

CRISPR arrays

The CRISPR arrays of NZ_LT827010_2

>merge|NZ_LT827010|2|701372-701478|CRISPRCasFinder
GGGGCAGCGTGGGTGGCTGGCGTGGTCGTGGGGGAGGGGCGGCGCGATGGCGGGACGCGTCGCGCGGTGGTGTCGGCAGTGGGGCAGCGCGGGTGGCTGGCGTGGTC

>NZ_LT827010|2|2|701372-701478|CRISPRCasFinder
GGGGCAGCGTGGGTGGCTGGCGTGGTC	GTGGGGGAGGGGCGGCGCGATGGCGGGACGCGTCGCGCGGTGGTGTCGGCAGT
GGGGCAGCGCGGGTGGCTGGCGTGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_043513440.1|703321_704185_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014687684.1|697999_700126_+|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588
NZ_LT827010.1|WP_014687687.1|702512_702818_+|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl|CDD|197385
NZ_LT827010.1|WP_014687688.1|702879_703092_+|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl|CDD|225328
NZ_LT827010.1|WP_052311867.1|693280_694249_+|hypothetical-protein	unknown	unknown	gnl|CDD|227278
NZ_LT827010.1|WP_043510757.1|711629_712589_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|366166
NZ_LT827010.1|WP_052311491.1|700559_701057_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379228
NZ_LT827010.1|WP_014687676.1|689389_690982_+|CHASE3-domain-containing-protein	unknown	unknown	gnl|CDD|226702
NZ_LT827010.1|WP_014687698.1|712640_713522_+|DUF3152-domain-containing-protein	unknown	unknown	gnl|CDD|371483
NZ_LT827010.1|WP_099343986.1|710067_711630_+|Daple	unknown	unknown	gnl|CDD|223021
NZ_LT827010.1|WP_014687677.1|690978_691434_+|response-regulator	unknown	unknown	gnl|CDD|381108
NZ_LT827010.1|WP_014687694.1|708703_708928_-|DUF3107-domain-containing-protein	unknown	unknown	gnl|CDD|378634
NZ_LT827010.1|WP_014687678.1|691426_692245_+|inositol-monophosphatase	unknown	unknown	gnl|CDD|238775
NZ_LT827010.1|WP_014687683.1|697289_697688_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014687695.1|708967_709627_-|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_LT827010.1|WP_172898846.1|696462_697191_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|212491
NZ_LT827010.1|WP_014687693.1|706540_708487_-|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223587
NZ_LT827010.1|WP_014687681.1|694509_696429_+|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_043513442.1|704170_705313_-|SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379330
NZ_LT827010.1|WP_014687679.1|692313_693087_+|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187605

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014687684.1|697999_700126_+|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	1.79539e-133
NZ_LT827010.1|WP_014687687.1|702512_702818_+|metal-sensitive-transcriptional-regulator	gnl|CDD|197385	cd10148, CsoR-like_DUF156, Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156. This superfamily includes various transcriptional regulators that respond to stressors including Cu(I), Ni(I), sulfite, and formaldehyde. It includes CsoR (copper-sensitive operon repressor) from Mycobacterium tuberculosis (MtCsoR), Bacillus subtilis (BsCsoR), Thermus thermophilus (TthCsoR), and Staphylococcus aureus (SaCsoR), Mycobacterium tuberculosis RicR (regulated in copper repressor, MtRicR), Escherichia coli RncR (formally known as YohL, nickel and cobalt-sensitive), Alcaligenes xylosoxidans NreA (nickel-sensitive), E. coli FrmR (formally known as YaiN, formaldehyde sensitive), and Staphylococcus aureus CstR (CsoR-like sulfur transferase repressor, NWMN_0026.5, SaCstR). CsoR is Cu(I)-inducible, and regulates the expression of genes involved in copper homeostasis. For example, TthCsoR binds the promoter region of the copZ-csoR-copA operon, and represses expression of these genes, which encode the copper chaperone CopZ, CsoR, and the copper efflux P-type ATPase CopA, respectively. In the presence of excess Cu(I), TthCsoR binds this ion, and is released from the DNA, allowing expression of the downstream genes. TthCsoR also senses other metal ions such as Cu(II), Zn(II), Ag(I), Cd(II) and Ni(II). CsoRs form a homotetramer (dimer of dimers). In the case of MtCsoR, two Cys residues on opposite subunits within each dimer, along with a His residue, bind the Cu(I) ion. These residues are conserved in the majority of members of this superfamily. Exceptions include the functionally uncharacterized Bacillus subtilis YrkD where there is an Asn instead of His (C-N-C), E.coli RcnR where there is a Thr instead of the second Cys (C-H-T), or TthCsoR and E.coli FrmR where there is a His instead of the second Cys and which have an additional N-terminal His (not found in those family members having C-H-C) that may also be involved in metal binding (H-C-H-H). A conserved Tyr and a Glu residue facilitate allosteric regulation of DNA binding. SaCstR regulates genes predicted to function in sulfur metabolism; it is thought that oxidation of the intersubunit Cys pair to a mixture of disulphide and trisulphide linkages by sulfite, results in a reduced affinity of SaCstR for the operator DNA. SaCstR exists as a mixture of oligomeric states, including dimers, tetramers and octamers. The sequence of SaCstR was not available at the time this hierarchy was curated and therefore was not included. Escherichia coli RncR represses expression of the gene encoding the nickel and cobalt-efflux protein RcnA. The gene encoding Alcaligenes xylosoxidans NreA is part of the nre nickel resistance locus located on the pTOM9 plasmid from thisbacteria. Escherichia coli FrmR regulates the formaldehyde degradation frmRAB operon.	2.75586e-34
NZ_LT827010.1|WP_014687688.1|702879_703092_+|heavy-metal-associated-domain-containing-protein	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	6.42092e-15
NZ_LT827010.1|WP_052311867.1|693280_694249_+|hypothetical-protein	gnl|CDD|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	0.00832088
NZ_LT827010.1|WP_043510757.1|711629_712589_+|alpha/beta-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	2.0229e-28
NZ_LT827010.1|WP_052311491.1|700559_701057_-|GNAT-family-N-acetyltransferase	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.01288e-10
NZ_LT827010.1|WP_014687676.1|689389_690982_+|CHASE3-domain-containing-protein	gnl|CDD|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	5.21241e-66
NZ_LT827010.1|WP_014687698.1|712640_713522_+|DUF3152-domain-containing-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.23531e-30
NZ_LT827010.1|WP_099343986.1|710067_711630_+|Daple	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.7503e-07
NZ_LT827010.1|WP_014687677.1|690978_691434_+|response-regulator	gnl|CDD|381108	cd17557, REC_Rcp-like, phosphoacceptor receiver (REC) domain of cyanobacterial phytochrome response regulator Rcp and similar domains. This family is composed of response regulators (RRs) that are members of phytochrome-associated, light-sensing two-component signal transduction pathways such as Synechocystis sp. Rcp1, Tolypothrix sp. RcpA, and Agrobacterium tumefaciens bacteriophytochrome response regulator AtBRR. They are stand-alone RRs containing only a REC domain with no output/effector domain. The REC domain itself functions as an effector domain. Also included in this family us Methanosaeta harundinacea methanogenesis regulatory protein FilR2, also a stand-alone RR. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.15055e-74
NZ_LT827010.1|WP_014687694.1|708703_708928_-|DUF3107-domain-containing-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	9.83402e-33
NZ_LT827010.1|WP_014687678.1|691426_692245_+|inositol-monophosphatase	gnl|CDD|238775	cd01517, PAP_phosphatase, PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine biosynthesis and provides increased salt tolerance when over-expressed. Bacterial members of this domain family may differ in their substrate specificity and dephosphorylate different targets, as the substrate binding site does not appear to be conserved in that sub-set.	3.15658e-46
NZ_LT827010.1|WP_014687695.1|708967_709627_-|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.1161e-17
NZ_LT827010.1|WP_172898846.1|696462_697191_+|SDR-family-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.4033e-55
NZ_LT827010.1|WP_014687693.1|706540_708487_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	9.11617e-154
NZ_LT827010.1|WP_014687681.1|694509_696429_+|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.34759e-97
NZ_LT827010.1|WP_043513442.1|704170_705313_-|SAM-dependent-methyltransferase	gnl|CDD|379330	pfam13679, Methyltransf_32, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.1008e-37
NZ_LT827010.1|WP_014687679.1|692313_693087_+|SDR-family-oxidoreductase	gnl|CDD|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.48277e-76

Protein sequences

>NZ_LT827010.1|WP_052311491.1|700559_701057_-|GNAT-family-N-acetyltransferase
MAPCSKFGIAEGATVEDREKDGYVLTDDAGRVDIDRVHRWLAEESYWATGRPLDLVTRSIDGSVPYSILHNGEQVGFARVVTDGATFAWVCDVFIAESHRGHGLGVWLVDTIVEDMTARGILRLLLATRDAHEVYRRSGFTPLEGPGRFMEIDRRPTRNAILGRS
>NZ_LT827010.1|WP_014687684.1|697999_700126_+|RecQ-family-ATP-dependent-DNA-helicase
MTADAAERASVRERAEQVLRRLAGEHARLREDQWRAIEALTVDRRRVLCVQRTGWGKSAVYFVATALLRAGGSAGPTVIVSPLLALMRNQVDAAARAGIRARTINSANLDEWSEIEQEIRAGTVDVLLISPERLNNPDFRDNVLPGLAHSTGLLVVDEAHCVSDWGHDFRPDYRRLRTFLAGLPGRTPVLATTATANARVTADVADQLGDALVLRGPLDRDSLRLAVLRLPEPAHRLAWLADHLERLPGSGIVYTLTVAAATETADFLRSRNFPVASYTGQVDDAERRAAEQDLLDNKIKALVATSALGMGFDKPDLGFVVHLGAPNSPIAYYQQVGRAGRAVEHAEVVLLPGPEDAAIWRYFASLAFPPEDQVRSVLAQLSADRPMSTQALEPLVDLRRNRLELMLKVLDVDGAVRRTRGGWLATGEPWTYDTARLRRVAEARSAEQQTMLEYAVTPTCRMEFLRRCLDDPEATPCGRCDNCAEPLFGPDVSAGSLAAAEAFLGRPGVEVAPKKMWPTGMTAVGISLKGKIGPAEQVEPGRAVGRLSDLGWGARLRGVVGPESPDAPIPAELAAAVVEVLKAWARGDDAWAQRPVGVVAVGSRRHPQLVHSLAEHIATVGRLPLLGVLTSAGSGEETFRGNSAQRVRALHNAFTVPPEVAAGLTVHQGPLLLVDDLVDSGWTMALAGRTLRQSGAHSVLPLALAVAS
>NZ_LT827010.1|WP_014687683.1|697289_697688_-|hypothetical-protein
MSKTIAEKLLIKPNSTVWLSQPARLPLLTPMPEGVRETGSLAAAGTAVLFAEDAASVRAQLTEHRADLDKPSAFWIAYPKGNKADINRDTLWPIVADFDMRPCGQVAIDDRWSGLRFRPNRPDEGRFTGGSQ
>NZ_LT827010.1|WP_172898846.1|696462_697191_+|SDR-family-oxidoreductase
MMTRLAVVTGGGTGIGKATAGMLAGEGYDVIIVGRRPEVLADAVKWIGPQASAVTADAADPAQVPRIVEAVAGRAVDVLVNNAGAFIGGDDSTLDGVAARWRANLDSNVLTAVLTTTALLPLLRRPGGKIILTSSIAAQRGGGGPYSAAKSALHGYALDLAVNLGGEGITANVISPGYITDSEFFDGRMTPEGHAKRVDSALVKRAGEPQEIAEAVRWLVGPGGGFVTGQIVNVNGGTVLGR
>NZ_LT827010.1|WP_014687681.1|694509_696429_+|protein-kinase
MGRTERNGHEGSLRIAGRYRLVEKLGTGGMSVVWRAYDETLSRDVAVKVLTPQLATDRAFRDRLRQEALAAARLCHPHITGVYDFGEALLSDHLTVPYVVMELNDGESVGARIGRQGTLDWREAVMVCAEVASALATAHARGVVHRDVTPANVMLTGAGAKVVDFGISAVVGQRDAGPDGSLLGTPAYLAPERLGGAPVSPATDVYALGLLLYRALTGRMPWPAASTTEALRAHLYADPDPVPDVPGMPAAVADLCLRCLAKAPADRPVSAEVARALAATVGVRPIIPPLRPGERPAVPVARAVVPAPAGSEAPRRARLSWLSGSPHRRLRRPAAPHGASGRSGSSYGSVAESGPGLPDRRPWSSGPSCRLRLRELRLRAALRFGTVLRTGAVHPLGNGLFLGSRLRQAGAVAAWVRHGRPARARNRLSAAAALATVVLLAGSALTWSARREAADADQSSASAAGPGADTTQRVRCSVQYQVRRDSGGAFEARMTVLTTGGSAGWRLEFSFPGTQRLAGPPRSVAQHGRRVVVRGAGRSRVITLRGGYRDRNPLPLAFAMNGHPCRAEVLGVVSDPATKDDAVSAASAKDDRPGPEETIHQRKRPPSRHGGARRKAAPSPADPSPAAPAKPNSGFSLAL
>NZ_LT827010.1|WP_052311867.1|693280_694249_+|hypothetical-protein
MVAATLAAVLVVSGTPARAADPEGGTKALRANLEAAAKGYDLAKTKLAESKKRQTQLTATLKAAQTRVDGLTRRVAAVANRSYQMGRMNTMMLLLNSGSPDSFVERVQGLDMLAQLDGSTLAAYKTDIDTTKKAQTALSAEIIEQNRQVNVMAQKKKQAEIALGAVGGGSVGGFVSADSAAAAPAPRNSDGSWPKESCTVDDPTSTGCITPRTLHAYQEARSDGFTHYTVCWSQRDSGEHPKGRACDFSANPSTFKDAAATGSDKAYGDRLAAYFVKNADALGIMYVIWYRQIWMPSTGWRAYSASGGPSVVHTNHVHLSML
>NZ_LT827010.1|WP_014687679.1|692313_693087_+|SDR-family-oxidoreductase
MTSYLDELFGLNGRTALVTGGSSGIGREIALALGRAGARVVLLARRAGPLAEVVAELEKHGAEGGAITADLADRSAVRSAVGEMNSRYGEPDILVNSAAVNLRPPLDELAEDVWDLTVEANLTSPFLLGQAFGPGMAARGWGRIINIASQQAFRAYGNSGAYGAAKAGLVGLTRSQAEAWSRHGVCANAIAPGVVHTPLTEPVFGDPSKVAAHAARTMIGRNGLPEDFAGCAVFLASGASQAVTGQTLFVDGGYSAT
>NZ_LT827010.1|WP_014687678.1|691426_692245_+|inositol-monophosphatase
MLDQVSDLVREVAQTVVLPRFQRLDSADVHQKAPGDLVTIADQESERALTRGLTALLPGSTVVGEEAVAADPAVRDRIDEGGAVWIVDPVDGTNNFAAGRTPFCVMVALVRERETVAAWILDVVEDSLTVAEAGSGTFRDGVRVKARADDPPAGDLHGVIANKYFPPDMQAHIDAHAGALGGYTPGRHCAGYEYPAIATDAQQFGMFWRILPWDHAPGTLIVREAGGVARHLDGVEYMPINRRKGLLVAGNEEIWHTVQNTLFPDGPPVIED
>NZ_LT827010.1|WP_014687677.1|690978_691434_+|response-regulator
MSTEFRDSGTPIEVLLVEDDPGDVLMTQEAFEEHKVRNRLTVVSDGAEALAYLRREGQFAEAVRPDLILLDLNLPRRDGREVLEEIKNDDDLGRIPVVVLTTSSADEDILRSYQLHANAYVTKPVDFERFIAVIRQIDEFFVSVVKLPPRA
>NZ_LT827010.1|WP_014687676.1|689389_690982_+|CHASE3-domain-containing-protein
MNVRTWSLRGRIVALCAVVGLILTALGIFAATTAATHNRQLDDVLNRVSPMRAASETLGTALVDQETGIRGFAITGRDASLEPYRQGLVEQNTQVSRIDGFLRPDDGQIRADLAAVRARIDDWHRDVAEPVIATVRDQGAAAGQAKVEAGDTRQFDAVRDALSVMQTHIQTLRAHSAAAAKESSHTMVAIEIAAAAIVVLAGIFLLLLLDRLISRPILELAGQVRDVAAGDYERHIESSVGAPELVGLAADIDRMRQQIATELTEVRDARQQVEWVNQQLQSQAEELTRSNRDLEQFAYVASHDLQEPLRKVASFCQLLQRRYAGKLDDRADQYIGFAVDGAQRMQRLINDLLAFSRIGRLTSGFTDVDLDRVLGDVKSQLDARAGEDGEITWGRMPTVEGEEPLLTTLFVNLIGNSLKFRRPDVAPRVRVTAERDGSEWKFNVRDNGIGIEAEFADKVFVIFQRLHARDAYEGTGIGLAIVKKIVEYHGGRIWLDVDVSPGASIWFTLPALIGLDEPGEEHEEREAVGV
>NZ_LT827010.1|WP_014687687.1|702512_702818_+|metal-sensitive-transcriptional-regulator
MSEEANTGHGPHGYSGDKAALLGRLRRIEGQIRGLQRMVDEDTYCIDVLTQISAAKSALQAVAVGLLEDHLAHCVVDAARAGDPSDKVKEASNAIARLIKS
>NZ_LT827010.1|WP_014687688.1|702879_703092_+|heavy-metal-associated-domain-containing-protein
MAVTSTYTVQGMTCSHCVNAVTEEISALPGVAEVSVDLASGGVTVTSEAPLTDDAVRAAVDEAGYQLADA
>NZ_LT827010.1|WP_043513440.1|703321_704185_+|hypothetical-protein
MLIVVLFAGYGLGRLNNGTATPAAAGPSPTTGMVMNENMPHTHGTTGTGVTMAAALGGLSLSSDGLTLHPAATSFDAGHRARLSFVIDGPGGAPVTSYAIVHDKPLHLIIVRRDLTGFQHLHPTMATDGTWSIDLTLDRPGAYRMITDFTALAGGRQIATTLGTDLTVAGDYAPQPLPPADRRTTTGGFTVSYEGAPNTQAVQPVLISVTGADGRPATVEPYLGAFGHLVVLRRGDVAYLHIHPELQPVDGKVKFWVTAPGPGDYRMFFDFQVAGQVHTAEWTLTVG
>NZ_LT827010.1|WP_043513442.1|704170_705313_-|SAM-dependent-methyltransferase
MPQPLDQALAEVRELLLAPGLTRAVAAGRRRGQLPSVTRAQLRPVTLKSGPKLQIVTDDGARPATRNVTPGAEAAAAIDELLAEPFGNWHIETDSATVQVRITKKGEAQVHRAATVAAPVAQDHDRAKQWLLDPGDPLFEVIGGNAAKRRQIDAFLRALAATLPDELPPTLRVVDLGCGNAYLTFAAYRYLAGRGVTLQIAGVDVREDQRVRNNAVAAQLGCAAEVSFVAGTIEEAELPFTPDLVLALHACDTATDQALARAVRWEARWVLAAPCCHHDIAAQLKGGAAPSPYAEFTRHAIVRERFADVLTDSLRAALLRLHGYRVDVVEFIDSAHTPRNLMLRARRSGAAATPEQHAEYDALIRQWGVTPALSRLLADG
>NZ_LT827010.1|WP_014687693.1|706540_708487_-|DEAD/DEAH-box-helicase
MTDIEQALIPVTNRAPVRPDSPTFADLGVRPETVEALAKAGITHAFAIQEYALPIALRGTDLIGQAPTGTGKTLGFGLPLLERVLAPSEGADGRPQALIVVPTRELGLQVARDLAAAGSTRGVRVLPIYGGVAYEPQVEQLKKGVEILVGTPGRLLDLAKQKQLKLNAVAALVLDEADRMLDLGFLDDVEKILAMLPEQRQTMLFSATMPDPIVALSRRFLRNPMTIHAGHTTDSGPNPLTKQVVYRTHPLNKIEMVSRILQARDRGLTMIFTRTKRAADKVSEELDFRGFAVAAVHGDLGQGARERALRAFRSGKIDVLVATDVAARGLDVSGVTHVLNYDCPEDPETYTHRIGRTGRAGATGVAVTFVDWEDMPRWVLIDKSLVLGMPEPPETYHTSPALYADLDIPSDVSGTLPTAERNRAGLSAEIEEDLGGGGRGRRSSRPARGGRSRGGSGSAPAAPSDPASPAGDGGDRPQRQRRRRKVVEGPASELGGTPSAPALESPAEPSAVAPSGDEPAPRSRNRRRRAPATTVEFSDTASAATDAPATASVATTAAPATSDPATTAPAAAAPAAAGPAAAGPAAAGPAAPVAEAAPAAAVAAEPAAESASTGDAAPRRRRRRTTRADEPADSMSAGSEAGVGTAEA
>NZ_LT827010.1|WP_014687694.1|708703_708928_-|DUF3107-domain-containing-protein
MEVKIGVQQSPRELVLESAQTPAEVEQAVSEALAKDGVLSLTDEKGRKVIVPVTKLAYVEIAEASHRPFGFTTR
>NZ_LT827010.1|WP_014687695.1|708967_709627_-|TetR/AcrR-family-transcriptional-regulator
MTAASGGAQTTRPTRLPRSARRKQLLAAAQQIFVAHGYHAAAMDDIAERAGVSKPVLYQHFPGKLELYLALLDTHCDAIIAKVRGALEATPDNKERVKGAVRAYFDFMDHESEAFRLVFESDLRNDPQVRQRVERVEQGCIVALTETIISDTGLRPDQAQLLASGLAGASGAAAQYWLANGRRTPKAEAESLVAALIWRGIASFPLQGGSTAGTAPEIG
>NZ_LT827010.1|WP_099343986.1|710067_711630_+|Daple
MPPSGAAEPTPWPAERSRLADILGHRPRPVDTASTGPAPSSAPPYPYEGDLDDSYHSATAQRAAVPMPRPVPSARGDWQPAEPGPTLGDPLSRTDAPSEPIRSRHALVNDTLAQGLPRVEPAAPQGDQRSVDNEARTGLPTYDASSFSRRAYEPSAPPAFPAPVFPGYSGTPEEVAAALGEPSDALPQRVPAQPDVPRVPEPPSVEPSAEAPALARIATHLRRGDVVPAQERQEGFDVQAILAAVREVDGVRDASLKATPAGAHSLRLDLADGADAAEVSRHVARLLAERMGLDAAMPGGMPAGPLPADPLSPGPLQSSPTPPPTPAPRPARASVKPVSPAPVPTPAPVSAAPVSTPPAPATERAAVTPRDLNGPRPLDPGDRPGPRVLIENVHVNTFGADASVEVRLRAGDRTASGVATGPAVDGYLLRLCATATAGAVDELLAVSTHTDGPARCFVEHAAAVSFGSTQVAVVVLLLSCAGGGWVEQLSGSAVVTGDDRHAMVRATLAAVNRRAEALLA
>NZ_LT827010.1|WP_043510757.1|711629_712589_+|alpha/beta-hydrolase
MKGAMLAGEDTLLPEGEVPPPWPARRVEVGGAMLHVRDTPALGPDAEPAVYVHGLGGSSQNFTDLAGLLADRFDGQAVDLPGFGYSDPSPRYSIPAFAATLIDYLDASGRGPVHLVGNSLGGSISVRVAALRPDLVRTLTLISPAMPFLDPRRTAQGPVLPLLALPGAERLMAWALTRVTAEQMAEQVLAACFGDTSKVHPQRRAEAMAEIQLRYTVAHYPRAYLGTLRGLVGSFLRAYLPGVNSQWRLAAQIQAPTLVIGGLTDKLVDPRVPVQVARTIPDSRLLILPGVGHVAQMEVPRLVARAIVGMLEDIRAPHR
>NZ_LT827010.1|WP_014687698.1|712640_713522_+|DUF3152-domain-containing-protein
MVPSGTPTLEPPARATDRWRQWWPALFAITLVLLVVITVAVRHSGRPTPSAAATPSPAASPSAAPTSAAPTLEHTSAPPSAGPTSLDPEILQVPGAVPTHGSGDFVYAVKRGAVLGGKGPIRRFHVAVEKGSGEDANAFATLVVSTLGDARSWVGDGNLRLQMVDADDHADFTVYLATRETAGEMCQRGGTNIHIGGVPYTSCRVPGAAIINLDRYRKSAKPYLAAKIPLATYRMYVINHEVGHELGHHHEGCPEPGGPAPVMVQQTLMLRGCVPYSWPRLDNHPFTGPSVSH

Crispr_ID: NZ_LT827010_3

• CRISPR_ID: NZ_LT827010_3
• CRISPR_location: 737748-737850
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_3

Consensus_repeat	Method
CCCGTGACCGGTCCTGCTCCGACCC	CRISPRCasFinder

spacers of NZ_LT827010_3

>3.1|737773|53|NZ_LT827010|CRISPRCasFinder
CGCTGGGAGGCCACCCCGTGGCCGCTTCTGCTCCGACCCGGCCGGGTGTCCAC

CRISPR arrays and Neighbor proteins around NZ_LT827010_3

CRISPR arrays

The CRISPR arrays of NZ_LT827010_3

>merge|NZ_LT827010|3|737748-737850|CRISPRCasFinder
CCCGTGACCGGTCCTGCTCCGACCCCGCTGGGAGGCCACCCCGTGGCCGCTTCTGCTCCGACCCGGCCGGGTGTCCACCCCGTGGCCGGTCCTGCTCCGACCC

>NZ_LT827010|3|3|737748-737850|CRISPRCasFinder
CCCGTGACCGGTCCTGCTCCGACCC	CGCTGGGAGGCCACCCCGTGGCCGCTTCTGCTCCGACCCGGCCGGGTGTCCAC
CCCGTGGCCGGTCCTGCTCCGACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014687731.1|747349_748339_+|aminoglycoside-phosphotransferase-family-protein	unknown	unknown	gnl|CDD|366736
NZ_LT827010.1|WP_014687720.1|733928_734285_+|NADH-quinone-oxidoreductase-subunit-K	unknown	unknown	gnl|CDD|180218
NZ_LT827010.1|WP_014687732.1|749001_749493_+|YajQ-family-cyclic-di-GMP-binding-protein	unknown	unknown	gnl|CDD|213038
NZ_LT827010.1|WP_043513448.1|730480_730984_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_LT827010.1|WP_014687717.1|731701_732661_+|NADH-quinone-oxidoreductase-subunit-H	unknown	unknown	gnl|CDD|376297
NZ_LT827010.1|WP_014687726.1|741413_742421_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274646
NZ_LT827010.1|WP_014687728.1|743297_743906_+|MOSC-domain-containing-protein	unknown	unknown	gnl|CDD|225167
NZ_LT827010.1|WP_014687718.1|732763_733363_+|NADH-quinone-oxidoreductase-subunit-I	unknown	unknown	gnl|CDD|235637
NZ_LT827010.1|WP_014687724.1|739772_740678_+|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|235102
NZ_LT827010.1|WP_014687721.1|734281_736195_+|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|235836
NZ_LT827010.1|WP_014687723.1|737905_739360_+|NADH-quinone-oxidoreductase-subunit-N	unknown	unknown	gnl|CDD|235603
NZ_LT827010.1|WP_014687729.1|743927_744230_+|N-acetyltransferase	unknown	unknown	gnl|CDD|379642
NZ_LT827010.1|WP_014687727.1|742440_743253_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225928
NZ_LT827010.1|WP_014687713.1|728269_729571_+|DUF2252-domain-containing-protein	unknown	unknown	gnl|CDD|313268
NZ_LT827010.1|WP_014687712.1|727722_728259_+|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl|CDD|235797
NZ_LT827010.1|WP_014687730.1|744688_745246_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NZ_LT827010.1|WP_014687719.1|733359_733929_+|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|376343
NZ_LT827010.1|WP_014687714.1|729575_730481_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014687725.1|740880_741357_+|DUF1707-domain-containing-protein	unknown	unknown	gnl|CDD|377959
NZ_LT827010.1|WP_014687716.1|731081_731702_+|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl|CDD|376317

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014687731.1|747349_748339_+|aminoglycoside-phosphotransferase-family-protein	gnl|CDD|366736	pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides they include: aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.	1.90566e-09
NZ_LT827010.1|WP_014687720.1|733928_734285_+|NADH-quinone-oxidoreductase-subunit-K	gnl|CDD|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	1.31589e-25
NZ_LT827010.1|WP_014687732.1|749001_749493_+|YajQ-family-cyclic-di-GMP-binding-protein	gnl|CDD|213038	cd11740, YajQ_like, Proteins similar to Escherichia coli YajQ. In Pseudomonas syringae, YajQ functions as a host protein involved in the temporal control of bacteriophage Phi6 gene transcription. It has been shown to bind to the phage's major structural core protein P1, most likely activating transcription by acting indirectly on the RNA polymerase. YajQ may remain bound to the phage particles throughout the infection period. Earlier, YajQ was characterized as a putative nucleic acid-binding protein based on the similarity of its (ferredoxin-like) three-dimensional topology with that of RNP-like RNA-binding domains.	7.64252e-83
NZ_LT827010.1|WP_043513448.1|730480_730984_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	1.65525e-32
NZ_LT827010.1|WP_014687717.1|731701_732661_+|NADH-quinone-oxidoreductase-subunit-H	gnl|CDD|376297	pfam00146, NADHdh, NADH dehydrogenase.	3.33621e-111
NZ_LT827010.1|WP_014687726.1|741413_742421_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	3.02567e-149
NZ_LT827010.1|WP_014687728.1|743297_743906_+|MOSC-domain-containing-protein	gnl|CDD|225167	COG2258, COG2258, Uncharacterized protein conserved in bacteria [Function unknown].	3.29087e-63
NZ_LT827010.1|WP_014687718.1|732763_733363_+|NADH-quinone-oxidoreductase-subunit-I	gnl|CDD|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	1.80187e-39
NZ_LT827010.1|WP_014687721.1|734281_736195_+|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	2.58298e-148
NZ_LT827010.1|WP_014687723.1|737905_739360_+|NADH-quinone-oxidoreductase-subunit-N	gnl|CDD|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	5.12986e-71
NZ_LT827010.1|WP_014687729.1|743927_744230_+|N-acetyltransferase	gnl|CDD|379642	pfam14542, Acetyltransf_CG, GCN5-related N-acetyl-transferase. This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule.	3.55281e-30
NZ_LT827010.1|WP_014687727.1|742440_743253_+|GNAT-family-N-acetyltransferase	gnl|CDD|225928	COG3393, COG3393, Predicted acetyltransferase [General function prediction only].	6.23179e-13
NZ_LT827010.1|WP_014687713.1|728269_729571_+|DUF2252-domain-containing-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	1.04666e-126
NZ_LT827010.1|WP_014687712.1|727722_728259_+|NADH-quinone-oxidoreductase-subunit-B	gnl|CDD|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	4.65798e-87
NZ_LT827010.1|WP_014687730.1|744688_745246_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	8.128e-23
NZ_LT827010.1|WP_014687719.1|733359_733929_+|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|376343	pfam00499, Oxidored_q3, NADH-ubiquinone/plastoquinone oxidoreductase chain 6.	2.24277e-32
NZ_LT827010.1|WP_014687724.1|739772_740678_+|zinc-metalloprotease-HtpX	gnl|CDD|235102	PRK03072, PRK03072, heat shock protein HtpX; Provisional.	1.19828e-153
NZ_LT827010.1|WP_014687725.1|740880_741357_+|DUF1707-domain-containing-protein	gnl|CDD|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	1.72742e-14
NZ_LT827010.1|WP_014687716.1|731081_731702_+|NADH-quinone-oxidoreductase-subunit-C	gnl|CDD|376317	pfam00329, Complex1_30kDa, Respiratory-chain NADH dehydrogenase, 30 Kd subunit.	4.14805e-47

Protein sequences

>NZ_LT827010.1|WP_014687721.1|734281_736195_+|NADH-quinone-oxidoreductase-subunit-L
MTTDVLGALLPGIPLLLGLLGLTLRPGDGGPRRLAATLGIAGAALALLDAIALLAITTSRAAPLAAGTTWARFGDIEVTLGFAVGPAALYVALAVCVVALCVQVYSTTYLHDDPRYAPYAAQVALFTGAMLLVVSSGDLIGLLIGWEVMGACSYLLIGHDRRLPEAPAAAVKAFLVTRVGDVGFLLGIALLVAGAGTSRLSVVLTHSYGHGTLIAALLLLLAGVAGKSAQFPLHTWLPDAMAGPTPISALIHAATMVAAGVYVVFRTFPLFQQSPAALATLAVMSSITILLGALSAMAQDDMKRVLAWSTVSQIGYMTGALAVGSPAAALFHLLTHAAFKALLFLAAGAVIHTVGGNHLSRMGGLRTHMPVTFWSFVIGLSALAGLPPLAGFWSKENVLTAAAHATDGGGTAPVWAAWLVWVAALLGVGLTAWYATRLLLRAFFGPSRAHGPAGPHWEVGFDDARYQSPAVPHDPPGPMRWPILLLAIPAALLGLAAFAPGFRHALELDDPHLSVAILLPMLLLATGAGTAWWLWWAVPGADPAEALGRARPLFAAGFHLDHVQSLLVVRPAKALARFATAADERVVDAAVEGAGTATRGLGGMFADAHRASLPGAAVLVLFGALILSVVAWLGALG
>NZ_LT827010.1|WP_014687720.1|733928_734285_+|NADH-quinone-oxidoreductase-subunit-K
MHVTVPYVIGAWLFGLGAYGVVRRRNAILVLMAVELMLNAVNLILVTADVSLRPTLRGVPSESWATPNAQPGSGGVFALFVIVLAAAEVGVGLAIVLQYYRMRRAVAIDEVALDEVDQ
>NZ_LT827010.1|WP_014687719.1|733359_733929_+|NADH-quinone-oxidoreductase-subunit-J
MTVADVLMLALGAVAVGSGALVVTSAHLVRSGLYLVVSLGAIAGLYLVLGAELVAWTQVLVYVGAVVVLLLFAVMLTRAPIGPSPDLDRPAGPSALIGAGVGLGLAALFADAFRWIEYPRAAPGTAERIGAQVFGTWVLPFEVLSILLLSALVGAIVLSRPDIGRRTGHPSAPGETTDRQTDEDEEVPA
>NZ_LT827010.1|WP_014687718.1|732763_733363_+|NADH-quinone-oxidoreductase-subunit-I
MTDDGDHLVPGKGLINGLAVTLKTLTRKTITQQYPDVEPELPPRSRGVIALLEENCTVCMLCARECPDWCIYIDSHKEEVVVPGAARARQRNVLDRFDIDFSLCMYCGICIEVCPFDALHWTPEFEYAETDVLSLLHDKGRLGEWMRTVPPPPAHDVLGEPSKEEATAARKAAGPGAATAAKTARPATVRPQQRPESQQ
>NZ_LT827010.1|WP_014687717.1|731701_732661_+|NADH-quinone-oxidoreductase-subunit-H
MPLWLDLLIRVAAVMVGFLVLPLLVGQAEHKVMAHMQGRVGPMYAGAFHGWAQLVADGVKFVQKEDVHPDGADRPVFRLAPIVALFPYLVVILTLPLGPHGLVAQRLDIGLFLVLAILGIGVVAVLMSAWASANKYSLLGGLRGAAQLLGYELPLVLAAASVAMAAGTLSLPGIVEAWRPWWLIWQAPAALVFFIAGLAEIRRPPFDMPIADSELVFGYMTEYTGLRFAFFLLAEYVGIIVIAALTTVLFLGGWHGPFADHLGWLWTLLKMAALSFVIIWFRVTYPRLREDQLQRLCWLILVPVSLAQLVLTVAVKSLL
>NZ_LT827010.1|WP_014687716.1|731081_731702_+|NADH-quinone-oxidoreductase-subunit-C
MTPEEVGERLVHLMETDDPGLGVVTAGVSGGGPGHSRAVVDVPVARWWHAATIARDPGALGCDFFDWLSAVDELDDGFDVVAHLWSTRRRHGLLLRTRVPRADPEVESLVDLYPGADWHERETFEMFGIVFARHPGLRPLLLPPEFEGHPLRKEFVLAARVAKPWPGAKEPGESEHGTAKRAPMRPPGVPDPSEWGPRRTRGGEAG
>NZ_LT827010.1|WP_043513448.1|730480_730984_-|sigma-70-family-RNA-polymerase-sigma-factor
MSAVPPDPPSFDEVYAAHYADLTVQLYAYFGDRQEAQDVVQEAFCRAFTRWRKVSGYGDPVGWIRRVAWNLAVSRWRRVRTSIGFLRRQTVAELHTEGPGPDRVALISALATLPGAHRRALVLHYLADMPITEVARREGVAEGTVKSWLHRGRAAMAARLNLTIGGE
>NZ_LT827010.1|WP_014687714.1|729575_730481_-|hypothetical-protein
MADQIERLFADLRTDTLPRIRPPGADAARRTVRRRRRRAAAVTGIGLAVLAVAAFTTPLRLSSPAEPAAPLSQAERDSLALDAARVIRLHDYPQTNGGTITGDGPLVTLDVLPGEYDFVAACAGQAGTVDLRAGETHLELPCGPAPDKKAITVAVTGRRQQISVAARSDPAALGRVGIGWALNLSEKSRAQLMAAARQAIGDNASSTFLDDNGASGVQDNSVRAGSYRVTAACIGTGPVHGQAGNQQATGPFHPLKAFVVECDGKAHDFDVTMPAGSKMGFFEFSTVASAQGALGYRVTRR
>NZ_LT827010.1|WP_014687713.1|728269_729571_+|DUF2252-domain-containing-protein
MSSASRADFIVDVLAREFGELMAIDPTAFRRKFRKMAASPFAFYRGSASLFYADQVGDFRDDSYLDERTSRVWIHGDLHAENFGTYMNSSGRLVFNVNDFDEAYVGPFSWDLKRFSASVALIGYSKALSDDSISALVTTFAESYLTELRAIAQGGDDAIGSITLENADGVLRRVLQEARLNTRVALLDGQTTVDDYERRFSLGDGVFEVDEATVARVTAAFDRYLATLPDTGRPISTNIKDIKLRKGVGIGSAGLPSYNLLLEGHTEALENDVIIYMKQAQVPAVARWIDDERVRSYFKHQGHRTAESQRALQAHADPWLGYTELGGVGQLVAEVSPYAADLDWSDVNEPEELSGVIADLGRAVARMHSVADDESSHDLVDFSTEEAIVAVVDKDEKGFVAHLVDFAHKYGDQAREDHQDFVDVFRNGRIPGL
>NZ_LT827010.1|WP_014687712.1|727722_728259_+|NADH-quinone-oxidoreductase-subunit-B
MALPGVLGEPIRFVLNWGRRYSLWVFNFGLACCAIEFIASSMSRHDFMRLGVIPFAHGPRQADLMVVSGTVTDKMAPAIKRLYDQMPEPKYVISFGSCSNCGGPYWDSYAVTKGVDQIIPVDVYVPGCPPRPEALLHGILRLQEKIAAEQSGPGGVSRPDPLTRTAAALTAPVVAPPV
>NZ_LT827010.1|WP_014687723.1|737905_739360_+|NADH-quinone-oxidoreductase-subunit-N
MSQSVDHFALLPLYAAAGTAILAFLADLFLANRTAVLSATALGGLATAVLALVVGPEPGTFCTTGACSWLPTWPAAVTAALFAALTVGVLALSTPALRLGIAPAGEFCFLLACSMTGGVVIAYAGDLITLIVGLETLTLPLYVLVGLRRFAPGERPTTAGVSASLTFFLISVVSTAVTLLGAALNYAATGSVHLALLHPATGPFRPLAGVGVALLVIGLAFKVAAVPLHAWAPATYDGAPLPVAAYLSTASKLGGVLALAAIVARLDARAVMAVLAVLTMTIGNLVALRQTRMVRLLAWSSIAQAGYILAALALGAPGVPAALAYAVLFMVLEFIAFTVVTALRLPGADGGTILDHRGAARRNPWPGAALTLSLAGLAGLPPGLAGLFAKLSVVDVLIRHHWSWLAAVVVLNAVIALAYYIRVTATLYSLPPRIGMTVADPALMDAALHPRLPVSRPVAATLAVSVAVAIVLGFAPQLLFAALS
>NZ_LT827010.1|WP_014687724.1|739772_740678_+|zinc-metalloprotease-HtpX
MPKESNVHSHHNGLKTAALLGLLTGLILAVGYWLGGSTGLVIAVIFSLVTNAVSYFFSDRIALRAMGAQPVSEAEFPALHQIVRELAAQAGQPMPRLYVSPSMQPNAFATGRDPQHAAVAVTAGITRILDARELRGVIGHELSHVYNRDILISSVAGALAGIVTMLAQLAIFLPFGGSDDDDAPNPASLLLMLILGPLAASIIQLAISRNREFQADASGATLTGDPLALASALEKIHYGTQRMPLPAEGQLTSAAHLMIANPFRAEGIAALFATHPPMVERIRRLHEQASLTGGASRPYLR
>NZ_LT827010.1|WP_014687725.1|740880_741357_+|DUF1707-domain-containing-protein
MAKEVTGPGRRGEQIESLRAADSDRQLIADQLKGALDEGRLSLHEYDDRVAAAYAAQTYAELLVLVRDLPQPGTSAAEVRARQAAESRRESRRLPVALIVLWTVWAALAAVNLVVYALVRTTVDHEIYPWPVWMLVPGAALAAVTAGVQVLRHQQRRP
>NZ_LT827010.1|WP_014687726.1|741413_742421_+|LLM-class-flavin-dependent-oxidoreductase
MTRVPLSVLDLATVREGHGSADALRGTIATARAADELGYARFWVAEHHNMPAVASTSPPVLIGAVAAQTGRIRVGSGGVMLPNHMPFVVAEQFALLEALYPGRVDLGIGRAPGTDQATAAALRGVSPHLTVERFPEHLRTVLGLLGDARVAGAAGRLHATPAPETYPQVWILGSSTYGAQVAAALGLPFCYAYHFAIAADVDAALQLYRSGFQPSPGLPEPHVMVSASVIAAETTEEAEFLAGPSRIMALSLRTGRLGPIISPEQAATRELSDLDRQMLHALPGTQYAGTADEVVAGLDALVARTGADELMLAGTVYDPETRRDTLARIAKAWGR
>NZ_LT827010.1|WP_014687727.1|742440_743253_+|GNAT-family-N-acetyltransferase
MTWEIRSDLDRFAAVAGDFLRASPVRHTVFLTLIDNLRSRGLHAYGAGDPVFGWWITPGDDSVSGVLLQTPPHPVMFTALPAPAVPAAAAALRSRPLPGVNMLVDDLPAFVGSRAHQPGMRTRLHPLGTLTPPSPPGAARPAGPADRDLVTAWLTDFFAVTGEPRADVAAVVDELLPRVTLRVDDATPVSMAVRSRPAAGMIRILYVWTPPALRRHGYAAGATAAATRAALDEGAAEVVLYTDLDNPTSNALYHRLGYRPVEDRAVVTFA
>NZ_LT827010.1|WP_014687728.1|743297_743906_+|MOSC-domain-containing-protein
MGKDVPTTGINKKPVSAPVQVRAPGPRRTGLHSGIVGDHIGDTRHHGGDDQAVYAYATEDYAWWAANLGRDLAPATFGENLTTSGLDLRDGVIGEQWQFGSGLLLQVTFGRIPCLTFQNRMAEPRWVKRFSQANRTGAYLRVLTPGTLVPGDRITVTDRPSHGLTLTEAYEIYMHDPTRLPRLLEAPELPPAMLAEVTDRLT
>NZ_LT827010.1|WP_014687729.1|743927_744230_+|N-acetyltransferase
MEFTVAEVPDKGRFEARTDTGALAGVLTYQMTGPIVVFTHTEVDPAFEHQGVGSALARTALEDARARSRTVVPMCPFIAAWLDQHKEFEPLVARNTRRIK
>NZ_LT827010.1|WP_014687730.1|744688_745246_-|Uma2-family-endonuclease
MSVGVVDHVGPWTEDEYFALGETTDRIELIDGSLVVSPAPSMSHQRLSRRLANALDEGAEPAGLFVYEAINVRLNTGRIVIPDLAVVDQDEEAVTADASRVLLIGEIVSPSNAAMDRVLKMQLYAAAGIGWYLLVEHEAPDSLTLRLNRLDGQHYVEETVVKTGASLTSEYPFRFDLDTRSLVRR
>NZ_LT827010.1|WP_014687731.1|747349_748339_+|aminoglycoside-phosphotransferase-family-protein
MAAVIERWTVTGPEFRGFYNVNAVAQTDAGVAIVRSRIPATDQMDLRPLDEVAILEAIAGRVYAPQVWRTDPARRFFVCSFVGEATLNEISPRGTAVMMQQMDSIIGTMAALTTVPVSAFVAMQRDSISALGLPVTSTLDMLVSHLGLLANEAIERRPILAAALSLPSVDGIVSAIPQREVARPDVLMHCDLHRKNLRTGAPGGGLYVLDWELALVGDPLYDLAVHIHKMSYPEWQKEAFISAWKERVMPTGWSDRDFGAYLAIERSKSAYVDLLRSMQNVLQGTVDAETMAIKYRSKLVDLARVVDVPVPSVESIAAEFRAEAARNEK
>NZ_LT827010.1|WP_014687732.1|749001_749493_+|YajQ-family-cyclic-di-GMP-binding-protein
MAANPSFDIVSKVDRQEVDNAYHQAEKELSTRFDFRGTGTELAKSGEAFTITSETEERATAALDVFKEKLVKRNISLKSLDAGEPRQSGKTFKIDLKVLEGIESDKAKAISKKIRDEGPKGVQAQIQGDSLRVTGKKRDDLQAVIALLKAEDFGVALQFTNYR

Crispr_ID: NZ_LT827010_4

• CRISPR_ID: NZ_LT827010_4
• CRISPR_location: 1175208-1175369
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_LT827010_4

Consensus_repeat	Method
GTCGGCTCGCCGGCAGCC	CRT

spacers of NZ_LT827010_4

>4.1|1175226|18|NZ_LT827010|CRT
GGTCGGGTCCCGACCGCG
>4.2|1175262|18|NZ_LT827010|CRT
GGTCGTGCTTCGCCGGTG
>4.3|1175298|18|NZ_LT827010|CRT
TGCGGTGCTGTGCCCGTC
>4.4|1175334|18|NZ_LT827010|CRT
TGCCGTGCTATGCCCGTC

CRISPR arrays and Neighbor proteins around NZ_LT827010_4

CRISPR arrays

The CRISPR arrays of NZ_LT827010_4

>merge|NZ_LT827010|4|1175208-1175369|CRT
GTCAGCTCGCCGGCAGCCGGTCGGGTCCCGACCGCGGTCGGCTCGCCGGCAGCCGGTCGTGCTTCGCCGGTGATCGGCTCGCCGGCAGCCTGCGGTGCTGTGCCCGTCGTCGGCTCGCCGGCAGCCTGCCGTGCTATGCCCGTCGTCGGCTCGCCGGCGCGT

>NZ_LT827010|4|1|1175208-1175369|CRT
GTCAGCTCGCCGGCAGCC	GGTCGGGTCCCGACCGCG
GTCGGCTCGCCGGCAGCC	GGTCGTGCTTCGCCGGTG
ATCGGCTCGCCGGCAGCC	TGCGGTGCTGTGCCCGTC
GTCGGCTCGCCGGCAGCC	TGCCGTGCTATGCCCGTC
GTCGGCTCGCCGGCGCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_063714044.1|1176261_1176399_-|FXSXX-COOH-protein	unknown	unknown	gnl|CDD|275092
NZ_LT827010.1|WP_014688101.1|1168422_1169706_+|MFS-transporter	unknown	unknown	gnl|CDD|340913
NZ_LT827010.1|WP_014688108.1|1177133_1177466_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014688103.1|1170228_1172649_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|315987
NZ_LT827010.1|WP_014688114.1|1184321_1185332_-|beta-family-protein	unknown	unknown	gnl|CDD|373022
NZ_LT827010.1|WP_014688112.1|1180555_1182343_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|369272
NZ_LT827010.1|WP_014688100.1|1167397_1168369_-|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|181818
NZ_LT827010.1|WP_043510863.1|1182921_1183764_-|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl|CDD|378140
NZ_LT827010.1|WP_014688099.1|1165670_1167338_-|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl|CDD|274186
NZ_LT827010.1|WP_014688109.1|1177486_1177771_-|DUF427-domain-containing-protein	unknown	unknown	gnl|CDD|377265
NZ_LT827010.1|WP_014688097.1|1163230_1164466_-|type-II-secretion-system-F-family-protein	unknown	unknown	gnl|CDD|224376
NZ_LT827010.1|WP_014688111.1|1178944_1180354_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_085945627.1|1177898_1178948_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014688115.1|1185368_1186664_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224037
NZ_LT827010.1|WP_172898851.1|1164468_1165515_-|type-IV-pilus-twitching-motility-protein-PilT	unknown	unknown	gnl|CDD|225364
NZ_LT827010.1|WP_014688102.1|1169819_1170134_-|STAS-domain-containing-protein	unknown	unknown	gnl|CDD|132914
NZ_LT827010.1|WP_014688104.1|1172650_1174330_-|bifunctional-diguanylate-cyclase/phosphodiesterase	unknown	unknown	gnl|CDD|238923
NZ_LT827010.1|WP_014688107.1|1176610_1177084_+|hypothetical-protein	unknown	unknown	gnl|CDD|376829
NZ_LT827010.1|WP_014688095.1|1161681_1162467_-|A24-family-peptidase	unknown	unknown	gnl|CDD|377700
NZ_LT827010.1|WP_014688096.1|1162621_1163128_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	unknown	unknown	gnl|CDD|225076

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_063714044.1|1176261_1176399_-|FXSXX-COOH-protein	gnl|CDD|275092	TIGR04268, FxSxx-COOH, FXSXX-COOH protein. Members of this family are very short (~60 residue) polypeptides, among which the fifth and third to last residues are nearly always Phe and Ser, respectively. Because members occur in a conserved context with a putative peptide-modifying radical SAM/SPASM domain protein, we suggest that members of this family may be the modification target. The gene symbol fxsA reflects both the FXA motif and the proposed role as a ribosomal natural product.	0.000309725
NZ_LT827010.1|WP_014688101.1|1168422_1169706_+|MFS-transporter	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.32883e-86
NZ_LT827010.1|WP_014688103.1|1170228_1172649_+|tetratricopeptide-repeat-protein	gnl|CDD|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	7.1027e-07
NZ_LT827010.1|WP_014688114.1|1184321_1185332_-|beta-family-protein	gnl|CDD|373022	pfam14350, Beta_protein, Beta protein. This family includes the beta protein from Bacteriophage T4. Beta protein prevents the gop protein from killing the bacterial host cell.	3.16141e-80
NZ_LT827010.1|WP_014688112.1|1180555_1182343_+|SpoIIE-family-protein-phosphatase	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	1.30461e-35
NZ_LT827010.1|WP_014688100.1|1167397_1168369_-|DJ-1/PfpI-family-protein	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.02923e-105
NZ_LT827010.1|WP_043510863.1|1182921_1183764_-|bifunctional-DNA-primase/polymerase	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	5.01303e-32
NZ_LT827010.1|WP_014688099.1|1165670_1167338_-|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl|CDD|274186	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB. This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	0
NZ_LT827010.1|WP_014688109.1|1177486_1177771_-|DUF427-domain-containing-protein	gnl|CDD|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	8.12228e-41
NZ_LT827010.1|WP_014688097.1|1163230_1164466_-|type-II-secretion-system-F-family-protein	gnl|CDD|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	3.12579e-128
NZ_LT827010.1|WP_014688115.1|1185368_1186664_-|ATP-binding-protein	gnl|CDD|224037	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair].	5.2017e-12
NZ_LT827010.1|WP_172898851.1|1164468_1165515_-|type-IV-pilus-twitching-motility-protein-PilT	gnl|CDD|225364	COG2805, PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion].	5.33029e-172
NZ_LT827010.1|WP_014688102.1|1169819_1170134_-|STAS-domain-containing-protein	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	2.41087e-24
NZ_LT827010.1|WP_014688104.1|1172650_1174330_-|bifunctional-diguanylate-cyclase/phosphodiesterase	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.0646e-103
NZ_LT827010.1|WP_014688107.1|1176610_1177084_+|hypothetical-protein	gnl|CDD|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	0.00222235
NZ_LT827010.1|WP_014688095.1|1161681_1162467_-|A24-family-peptidase	gnl|CDD|377700	pfam06750, DiS_P_DiS, Bacterial Peptidase A24 N-terminal domain. This family is found at the N-terminus of the pre-pilin peptidases (pfam01478). It's function has not been specifically determined; however some of the family have been characterized as bifunctional, and this domain may contain the N-methylation activity (EC:2.1.1.-). It consists of an intracellular region between a pair of transmembrane. This region contains an invariant proline and two almost fully conserved disulphide bridges - hence the name DiS-P-DiS. The cysteines have been shown to be essential to the overall function of the enzyme in, but their role was incorrectly ascribed.	2.78865e-45
NZ_LT827010.1|WP_014688096.1|1162621_1163128_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	4.65367e-14

Protein sequences

>NZ_LT827010.1|WP_014688104.1|1172650_1174330_-|bifunctional-diguanylate-cyclase/phosphodiesterase
MARKALLDRTRRVVDDGVVLASLLLLVWPAADATDVTLTGRLVPLAAALCLGLAMLLVAPDRPVLRFAPTAAALAVSGIRHVQGELAPGAVWLLLGMAVAVLFRRWAVAGSDNALIREMTSQRALLARQAYRDPLTGVGNRKMFLERADHELSAASRTMTAVIVVDLDGFRELNDEFGHEVGDGLLRAAADRLAANVRANDVVARLDGDEFVVLLPGVEDEQAAVAVAERVLTELHRPLEVDGIKLTVRASAGVAITAGGETIDHVLREADQALHRAKLDGGGAARRFDPALFALEEQRRKAEGDIIRALDLGEFEVHYQPIVDLDGEHTVGVEALIRWQHPEKGLVPPGLFLELAEQLGLLPRLGGWVLEEACRQAVNWQRQFPGFEMNVNLSASQLSNPNLVGEVRAVLERTGLEPEHLVLELTESVALVDLVESARILTELKELGVRIALDDFGTGFSSLSHLSALPVDVVKIDRSFVQAMPESGGASVAEAVLHIARTFNLAPVAEGVEDAAQAEWLRDLACGRAQGYHFARPMPALGVTELLDKQADKDVPLAS
>NZ_LT827010.1|WP_014688103.1|1170228_1172649_+|tetratricopeptide-repeat-protein
MPIRGGLPPRNPRFVGREELLTRVRGLLGNGPVVLLPSPDHQLGGTGRTQLAIEYAYRHADSYELVWWIPAEQGAGMRAALAGLARKLGLPETRDLNRTLGAVRDALSRGEPFRHWLVVFENANRPEDIMPYLPSGAGHVLVTSRNPRWTAEVAQALPVPVLDRADATDLLRGRAPELSPEDADRLAARLGDVPIALDLAAAVRTATGWPVAEYLERYERRAAELAFPTPIRVTWGLAADALGEASPADRVLLELCTFLASAPISWQLLWAARTCPLDPEVARTVRVERRLRAAMRRIARFGLAGLDPSGERLTVHPLIRGMFGQELSSERHAELLRTVRAMLSAADPGDPDNPAGWYRYAELAPHLIHSDLLGGDAEEVRQLVINCIRFHYARGDYDSSRELAGSAVARWRDALGESAEQTLLASFHLANALRAVGRPADARALNLQTLRTQREVFGADDEATLATANSVGGDLRMQGHFGQARQLDADNLVRYRRLFGESFPTALRCANNLAIDLRLLGDFRGARALDEQTLRHRHAIFVDGHPETLASRAALAYDLFGLGDYAGVGTVLAGQAEQVAEDHPFALWAGRLTAMAAHRRGVAAAREMATENLAACRRRFGDLNVDTLATAVSLANCVRAAGDLAGAHELLERAVIRFHAVLGDEHPFTLAASAGLAGVVRAAGRYAEARTIDEEVLGGLRRSVGADHPFTLSCANGLAGDLFAAGEAQQARELAADTLRRSRVVRGADHPDTVACAWNLALADADETAQQQALTGLAKAYGDGHPIFRVTAAGQRLETDIDLPPL
>NZ_LT827010.1|WP_014688102.1|1169819_1170134_-|STAS-domain-containing-protein
MIEEVTSLDADGNTTTVSLRGEIDVLTVEQVRVALGEAVTGRPRQIVVDMAAVAFIDSTGLGALISGFQRARDQGIAFQLAHPSPNVRQILVLSGFLEVVQVTP
>NZ_LT827010.1|WP_014688101.1|1168422_1169706_+|MFS-transporter
MKARLHPAWSVAAVAFIALIGAAGFRSTPSVMLQPLHAEFGWSLGTISAAVSVNLMLYGLTAPFAAALMARFGIRRVAAAALGLVALGSGLTVLMHHSWQLMLCWGVLVGLGTGSLALGFVATITGRWFVRHRGLVTGILTAGGATGNLIFLPVLSRLVESHGWRTAALTVSAIALLVVPLILGRLRDHPQDLGTTALGGITEPPAPPAGNAVRTALTALRDAGRTRAFWLLAGGFAICGATTNGLVGTHFIPAAHDHGMPNTTAASLLALVGVFDVVGTIASGWLTDRVDSRVLLGAYYALRGLSLLVLPSILAATAHPGMLVFILFYGLDWVATVPPTVTLCREYFGAAGPVVFGWVFASHQIGAAIAATTAGLVRDQLGAYTWAWYGAGALALLASLLSLMLFAGKHLKPLAPGLGLAVPAAKA
>NZ_LT827010.1|WP_014688100.1|1167397_1168369_-|DJ-1/PfpI-family-protein
MRKNRAMPHVIAVLVLDGVVPFDLGVPAQVFGAARDGARNRFYELLFCGEGPVRAEAGFTVTPDHDLSVVARADTVLIPGIHLGGPVTDGSLPDAVREVLLAAARRGARIVSICTGASVLAAAGLLDGRPAATHWAWASRIGGLYPRVDWDFDVLFVDDGDVLTSAGVGAGVDLCLHIVRSDHGAEVANRAARRCVVPPWRDGGQAQYIERPVPAAANSGTEPTRTWVLDRLADPVTLEEMAAHARMSVRTFTRRFRDETGSSPRRWLLRQRVEHARLLLESTDLGVDVVARRAGLGSATALRQHLHATIGVAPSAYRRTFRH
>NZ_LT827010.1|WP_014688099.1|1165670_1167338_-|Flp-pilus-assembly-complex-ATPase-component-TadA
MDQTFRPLLDALKQIGVDPHAVDSAAEEAQRSGRPVRAVLINDQVVTEEQLTQAAAAAFGINTLDLVGFTPDPTALKRIPLPVVLRHRVLGLAINDGELVVGVTDPADVVALDDVRAATGMTVRPVVVARSEVRRIIEKLQRDDSDLGDLAGAGMDDSAGMAAQQTSTEDAPIVRYVNSLIEQAVMNRASDLHLEPTEDEMRVRYRIDGVLHEVDIVPRGVMAALTSRIKIMSGVDITEKRVPQNGRITALIRDRTVDLRTATLPTVWGEKIVLRVLDTGGIDLDLRKLGFTEHNLSRFEASFTKPHGMVLVTGPTGSGKSTTLYATLGRISKPEVNVITIEDPVEYRLRGINQVQVNVKAGLTFAAVLPAILRSDPDVVLIGEIRDGTTAQIAVEAALTGHLLLSTLHTNDAPGAVTRLTEMGIEPFLVGSSLDCVLAQRLARRLCDWCKEAYAPTEEEVLGARWPLEDLAFPQVLYRPVGCRNCANTGYKGRIALHEVMPVSPEIESLTIRRAPAGELREVALAQGMYDLRSDGLAKAAGGLTSIREVSRVAV
>NZ_LT827010.1|WP_172898851.1|1164468_1165515_-|type-IV-pilus-twitching-motility-protein-PilT
MLITLVESRGSDLHLTVGSPPMMRVDGSLRAVPGYGKLNAADTELLARAAVTPAQWQTFQAEQEMDFAHSIVGVSRFRGNLYRQRTSCGAVFRAIPHKIKPLDELGMPESVARFAHLPRGLVLVTGPTGSGKTTTLASLLDLANRSRADHIITIEDPIEFLHPHKRSIVNQREVGADTDTFASALKHALRQDPDIILVGELRDLTTTATALTAAETGHLVMATLHTQSATQTIDRVIDIFPPHQQLQIRAQLAASLQGVITQALAPRADGKGRAVICEILSATPAIRSLIREGKSHQIPSFMQAGSNEGMLAFDQHLAEKVREGIITMQTATEISHSPEELKRLVGRS
>NZ_LT827010.1|WP_014688097.1|1163230_1164466_-|type-II-secretion-system-F-family-protein
MSGTNKTFAYSTIDASGKKSKGTIEAPNEAAATHMLQQRGEVPLGLVEAGQGLQRELKIPGLGNRVKLKDLAVFARQFATMTSSGMSLLRSLSIMEEQTSSPPLKKAIGEVRSDVAAGGGLSASMAKHDRVFPRLMVAMIRAGETGGMIDRALEQIADSLEKDTALRGKIKSALTYPAIVLGFTFLLIAAMLIFIVPIFEAMFKNLGGELPAITQFLVTTSHNMWWIGPLVLGIGIGAAAAYKHQHRTSAEFRLKVDKLKLRMPVFGSLFQKLAMSRFSRNLGLLLNVGVPVMQALAVVGETTGNEVINIAMQDIQATVRDGQPMSGAMRNHKVFPEMVNQMIEVGEESGQISQMLDKVADFYDREVDAAAESLAASIEPIMVLVMGAVVGGMVVCLYLPMFTIYQNIQSS
>NZ_LT827010.1|WP_014688096.1|1162621_1163128_-|prepilin-type-N-terminal-cleavage/methylation-domain-containing-protein
MQNVIDRMIAKQAEIRAKKDDEGFTLIELLVVVVIIGVLVAIAVPVYLNYRQGAADKSAQSDVRGAISAVEQYYTGNGNTYPTNAATSIVANSTPASSITLPAQTGGTAGTITVSDKTELTYVPPSGTSSYKICAKNTGGSGKVYLYDASVGGSVKTASGITPTATGC
>NZ_LT827010.1|WP_014688095.1|1161681_1162467_-|A24-family-peptidase
MPLSPLLLVVGLLGLAVGSFLNVVIHRVPRDESLVHPGSHCPNCGHAVRNRHNVPVLGWLMLRGRCADCATPISARYPLVEAGTAALFVAVAARFGWSWALPGYLYLAAVAIALALIDLDVMRLPDKIVLPSYAVAAALLIPPALLAGDPTALLRGAAAAGLLYVLYRVLATFGMGRGDVKLAPLLGFHLGWLGWGAVAVGAFAAFLLGGVVGAILLATRVAGRKSRIPFGPYMLAGAFLAVFAAAPIAEWYAQLLIPASF
>NZ_LT827010.1|WP_063714044.1|1176261_1176399_-|FXSXX-COOH-protein
MIDVSESSLAELVVRDDSALDRCLRRLAATRSGPSEQIAGFNSAL
>NZ_LT827010.1|WP_014688107.1|1176610_1177084_+|hypothetical-protein
MLGGELGVGDGASRSGGAAAALADRVATLRASAAGAGGAVRVTVASSGNVTGLELDERSLGLGAPGLAAEILLTIHRAQAALAGRVAEAVASTVGAETETGRAVLDGFASRFPAPDEVPPAPVMPSAPPFPSFSAVPTLPHQSPGNGYEGGRDSRAR
>NZ_LT827010.1|WP_014688108.1|1177133_1177466_+|hypothetical-protein
MDNAELARMVEAEHPYRGKALFELCDRLAGDDDAVAKVAMLTRLTSLRRARLFDRVSLAWSAIIALLAAETENARAEAYAAFRALDPAEQRDMLDYLEVSAIEEAHPRIA
>NZ_LT827010.1|WP_014688109.1|1177486_1177771_-|DUF427-domain-containing-protein
MPKAIWNDEVIAESDDTVVLEGNYYFPLTSVREDVLIPSDTHTVCPWKGKASYYSLRADGRTAADAAWYYPDPKPDAAAVRDRVAFRKDVQVEI
>NZ_LT827010.1|WP_085945627.1|1177898_1178948_+|hypothetical-protein
MMTRLDELRGSGKAKRHNARTIAALTGNPGCNRRAVLDAAGVDKLKLAETVGFPGSFGQSRFALSRGNAFEAMLKADDCALLRTVLGASSASPYQDLGPDTDDTLGDRHARTATLLSTAEAALIDHPMLTLEVAGQTVYLEPDLVAYAHEGRLQVVEIKSFAIIDGQADSAKVSGAATQAAVYVLALRELLGRLGMDPQLVDHEVVLVCPENFAMRPVPVRLDVRKQLSTLRRQLARMASVGALVEALPPGLTFDLERPAAELTVALGHIAPRYAPECLSTCELSVYCRHEANGTTAALGRPVREALGGVETIGEVLALASGAQAPTAEQEEAAALLRAALRLREEALS
>NZ_LT827010.1|WP_014688111.1|1178944_1180354_+|hypothetical-protein
MSTLTALARAQAVAAGRAQPIATVRHLHVHEHPLVLIPLAMAGEANAPLAALVGTDPATPELLVVSQPRDRDERFRFADRLGQIIAAYVDSFADVTEDVPVDRGKDVRTRYADAPQIWVPNPAGVDFLRLFGRSTRFRTVDGEHPVPATVPLLGRWLTFFANSAEVPGSALLVNAVQALGLHWATGQSGTEDAQLAVLMAWIEEGAAAARAVENGPIAGPATDPDFDNRVLAPLIERRAPEMSDVLRDLMTPTWERMWRVPNLLRRLPVGERVGLRWDADKDAYTAFAQHLAEGGAPQPRRDGAVAAAARLQRLETAASRYAVQRAFDDPLVLAEYRLAGAAFAGVVTLAAPDRIDDSGKRPVLRPRIMVRTGEPVRVAAGTSLTSPARPSQKARVISVTAVGPEFDVLLELSGGMGRKLVAEPGSVPVVGERLILTTLSEEFRRGGALPDPSETPWTHGGPPTVEVPI
>NZ_LT827010.1|WP_014688112.1|1180555_1182343_+|SpoIIE-family-protein-phosphatase
MVLQWDVIGDTEQSVLADPVRLRSVRRLGEPGPDEAFDRVAMLVRKLVDAPLGVVSLVGAERQHLAGQVGMPEPFASGRSMPLTHSFSRHVVVNGRLVVIPDVRVDLRTRGNPSIEQLGAIAFAGAPITDPDGLVVGALCAADHEPRNWTQSEITLLTELAAVCSSEVCLRIARAAAEDARRAAESAHHQLELLTDLTESLAATMDLDEAMHRLGSLVTARLADWCVITYGDQPRVVAAHRDPTRNADMSRLAELTARSRTDLRTLATAARRPPRRAEGTDLLRGKVSDTEIAELATVAGLGSSVVAPIISPVRRRVVGSVLLVNGPDQAPFTAADERVAAEIGRRAGLAVENSRLYREQRHVAEVLQRSLLTELPDLPGVELHARYLPAQDGAAVGGDWYDAFAQPDGSVMVAVGDVSGHDIEAAATMGQLRNLVRGDAYGRPDEPGALLTQLDQALHGLRVPAAATAVLARVRQSWSGYAISFANAGHPPPLLLLPDGRVQVWWVPPEPLLGLPVPSDRTTTIRYVPPGSTLVLYTDGLVEDRDQLLDDGVARLAERLRESSAFPGDELCARLLEVAPRRTDDIALLLVRLTG
>NZ_LT827010.1|WP_043510863.1|1182921_1183764_-|bifunctional-DNA-primase/polymerase
MSLTAALAYARHGIPVLPVHSPERDGVCSCGKGARCDSPGKHPRLRHGLNEASTDPRQIELWWAHWPRANVGLRTGVVMDVADIDSAEGWHGLRHLLDGDIPAGPQVRTGSGGRHLWFHPTGYGNRVRLLPGLDWRGVGGYVLAPPSRHVAGTGYTWIRRPGHGLPISPAALRAMIAGPPPAPLRPVAHPDRYAEAALDAEADRVARATVGCRNDTLNRAAFALGRFVGAGLLDAGSVRRELEHAARRAGLGEAEIRGTIRSGLTAGRRQPFAHTPDHAA
>NZ_LT827010.1|WP_014688114.1|1184321_1185332_-|beta-family-protein
MTPNGAYRPILRPRRGEFTALAHLSADEAARITPIVELDPEVSIIPLLRELRPRTGELALDFGHVPEPTATAEQPLALAERLFRLGVATVPVLRPYESGRRLVSHGLAARMHRRRAVLRIQPHVDAGNPARADAIADRVLAITALDPNEVDLLIDLAETPCLAHADEVEERARRVLRWARLMPWRSVSVGSGAMPPNLDDLPTDRPVAVGRLDARVWERLGDPGVGYADYGVTSPVRRLGVQHHRQLPTLRYTTESDWWIYRWARRGGRSDDRCHDLCRTLVTSPQWPSAGARFSWGDAEIARRARTARGAGSSASWIAWSTSHHISHVLRTLPTG
>NZ_LT827010.1|WP_014688115.1|1185368_1186664_-|ATP-binding-protein
MSYISPAEEAATVIAAVLRDLRSHRHRGVVVDSPPGAGKSTLVVRAAGELAATGEPLMIVAQTNEQVDDLIERLGARSPDITVGRLSAVDYERSDRVKEHPHCRVAAKVADLAGPAVTIGTAAKWATVAEGSWPWAIVDEAYQMRSDALLRVAPRFERALFVGDPGQLDPFSTVEVERWTGLSWDPMQSAVAVLLRHNPELPVHRLPVSWRLPASAAPVVAEAFYPFTGFRSGTGPGDRTLHFEAPGETPLDQVLDTAAKSGWGLHELPARFTLRTDAEAAAACAQLAARALARGGVTESEAGSGPLTPGRIAIGAAHRDQAAAIRALLPPEAAGITVDTANRLQGREYDLTVVLHPLSGRRDATAFHLESGRLCVLTSRHRHACVVVARAGIPELLDAHPSTEPVHLNVPVKFPDGWEANQSMLAHLYRR

Crispr_ID: NZ_LT827010_5

• CRISPR_ID: NZ_LT827010_5
• CRISPR_location: 1847599-1847674
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_5

Consensus_repeat	Method
CTCGTCGTCCGCCGCTGATCGTCTT	CRISPRCasFinder

spacers of NZ_LT827010_5

>5.1|1847624|26|NZ_LT827010|CRISPRCasFinder
TCCGGCGCCGGTGCGGATCCGGGCGG

CRISPR arrays and Neighbor proteins around NZ_LT827010_5

CRISPR arrays

The CRISPR arrays of NZ_LT827010_5

>merge|NZ_LT827010|5|1847599-1847674|CRISPRCasFinder
CTCGTCGTCCGCCGCTGATCGTCTTTCCGGCGCCGGTGCGGATCCGGGCGGCCTGTCGTCCGCCGCTGATCGTCTT

>NZ_LT827010|5|4|1847599-1847674|CRISPRCasFinder
CTCGTCGTCCGCCGCTGATCGTCTT	TCCGGCGCCGGTGCGGATCCGGGCGG
CCTGTCGTCCGCCGCTGATCGTCTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014688718.1|1855371_1858158_+|leucine--tRNA-ligase	unknown	unknown	gnl|CDD|234743
NZ_LT827010.1|WP_014688701.1|1831630_1832305_-|monooxygenase	unknown	unknown	unknown
NZ_LT827010.1|WP_014688710.1|1842946_1846351_+|error-prone-DNA-polymerase	unknown	unknown	gnl|CDD|235553
NZ_LT827010.1|WP_014688711.1|1846393_1846768_+|serine-protease	unknown	unknown	gnl|CDD|366264
NZ_LT827010.1|WP_014688715.1|1850160_1852626_-|transglutaminase-domain-containing-protein	unknown	unknown	gnl|CDD|376628
NZ_LT827010.1|WP_014688721.1|1859820_1861041_-|DUF1727-domain-containing-protein	unknown	unknown	gnl|CDD|223840
NZ_LT827010.1|WP_014688700.1|1831055_1831634_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|273701
NZ_LT827010.1|WP_043513738.1|1841227_1842934_+|DNA-polymerase-Y-family-protein	unknown	unknown	gnl|CDD|176458
NZ_LT827010.1|WP_014688712.1|1846817_1847564_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|182918
NZ_LT827010.1|WP_014688720.1|1859091_1859805_-|glutamine-amidotransferase	unknown	unknown	gnl|CDD|225974
NZ_LT827010.1|WP_014688722.1|1861644_1862442_+|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_LT827010.1|WP_043513734.1|1838801_1839245_+|hypothetical-protein	unknown	unknown	gnl|CDD|376149
NZ_LT827010.1|WP_014688705.1|1836504_1837563_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197713
NZ_LT827010.1|WP_043511039.1|1852622_1853921_-|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NZ_LT827010.1|WP_014688714.1|1849105_1849498_+|DUF3040-domain-containing-protein	unknown	unknown	gnl|CDD|378610
NZ_LT827010.1|WP_014688717.1|1853923_1854961_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NZ_LT827010.1|WP_014688703.1|1833190_1835140_+|APC-family-permease	unknown	unknown	gnl|CDD|223605
NZ_LT827010.1|WP_014688719.1|1858316_1859030_-|TVP38/TMEM64-family-protein	unknown	unknown	gnl|CDD|223475
NZ_LT827010.1|WP_014688723.1|1863276_1863708_+|division/cell-wall-cluster-transcriptional-repressor-MraZ	unknown	unknown	gnl|CDD|234728
NZ_LT827010.1|WP_014688702.1|1832301_1833117_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212492

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014688718.1|1855371_1858158_+|leucine--tRNA-ligase	gnl|CDD|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_LT827010.1|WP_014688722.1|1861644_1862442_+|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	2.97736e-19
NZ_LT827010.1|WP_014688710.1|1842946_1846351_+|error-prone-DNA-polymerase	gnl|CDD|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NZ_LT827010.1|WP_014688711.1|1846393_1846768_+|serine-protease	gnl|CDD|366264	pfam00720, SSI, Subtilisin inhibitor-like.	4.45208e-21
NZ_LT827010.1|WP_014688715.1|1850160_1852626_-|transglutaminase-domain-containing-protein	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	8.4074e-27
NZ_LT827010.1|WP_014688721.1|1859820_1861041_-|DUF1727-domain-containing-protein	gnl|CDD|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.89631e-41
NZ_LT827010.1|WP_014688700.1|1831055_1831634_-|GNAT-family-N-acetyltransferase	gnl|CDD|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	8.94849e-08
NZ_LT827010.1|WP_043513738.1|1841227_1842934_+|DNA-polymerase-Y-family-protein	gnl|CDD|176458	cd03468, PolY_like, DNA Polymerase Y-family. Y-family DNA polymerases are a specialized subset of polymerases that facilitate translesion synthesis (TLS), a process that allows the bypass of a variety of DNA lesions. Unlike replicative polymerases, TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. The active sites of TLS polymerases are large and flexible to allow the accomodation of distorted bases. Expression of Y-family polymerases is often induced by DNA damage and is believed to be highly regulated. TLS is likely induced by the monoubiquitination of the replication clamp PCNA, which provides a scaffold for TLS polymerases to bind in order to access the lesion. Because of their high error rates, TLS polymerases are potential targets for cancer treatment and prevention.	1.00453e-40
NZ_LT827010.1|WP_014688712.1|1846817_1847564_+|methyltransferase-domain-containing-protein	gnl|CDD|182918	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM.	5.50645e-29
NZ_LT827010.1|WP_014688720.1|1859091_1859805_-|glutamine-amidotransferase	gnl|CDD|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	4.88342e-70
NZ_LT827010.1|WP_043513734.1|1838801_1839245_+|hypothetical-protein	gnl|CDD|376149	pfam18726, HEPN_SAV_6107, SAV_6107-like HEPN. SAV_6107-like HEPN.	4.85177e-28
NZ_LT827010.1|WP_014688705.1|1836504_1837563_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	2.5528e-08
NZ_LT827010.1|WP_043511039.1|1852622_1853921_-|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.32509e-37
NZ_LT827010.1|WP_014688714.1|1849105_1849498_+|DUF3040-domain-containing-protein	gnl|CDD|378610	pfam11239, DUF3040, Protein of unknown function (DUF3040). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	1.20901e-25
NZ_LT827010.1|WP_014688717.1|1853923_1854961_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.98717e-91
NZ_LT827010.1|WP_014688703.1|1833190_1835140_+|APC-family-permease	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	2.68948e-11
NZ_LT827010.1|WP_014688719.1|1858316_1859030_-|TVP38/TMEM64-family-protein	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.50505e-21
NZ_LT827010.1|WP_014688723.1|1863276_1863708_+|division/cell-wall-cluster-transcriptional-repressor-MraZ	gnl|CDD|234728	PRK00326, PRK00326, transcriptional regulator MraZ.	2.53771e-65
NZ_LT827010.1|WP_014688702.1|1832301_1833117_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212492	cd05327, retinol-DH_like_SDR_c_like, retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs. Classical SDR subgroup containing retinol-DHs, LPORs, and related proteins. Retinol is processed by a medium chain alcohol dehydrogenase followed by retinol-DHs. Pchlide reductases act in chlorophyll biosynthesis. There are distinct enzymes that catalyze Pchlide reduction in light or dark conditions. Light-dependent reduction is via an NADP-dependent SDR, LPOR. Proteins in this subfamily share the glycine-rich NAD-binding motif of the classical SDRs, have a partial match to the canonical active site tetrad, but lack the typical active site Ser. This subgroup includes the human proteins: retinol dehydrogenase -12, -13 ,and -14, dehydrogenase/reductase SDR family member (DHRS)-12 , -13 and -X (a DHRS on chromosome X), and WWOX (WW domain-containing oxidoreductase), as well as a Neurospora crassa SDR encoded by the blue light inducible bli-4 gene. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	6.55504e-70

Protein sequences

>NZ_LT827010.1|WP_014688712.1|1846817_1847564_+|methyltransferase-domain-containing-protein
MDTAIARTGRPLVTARTAAVWAVLRRELERNAGRELTVLDVGGGTGGFAVPLAEAGHTVTVIDASPDALAALTRRAADAGVAGRVRAVQGDGDALAGLVEPGSADLVLCHAVLEVVDDPARVVTAIAGALRPGGALSLLVAGRAAAVLGRAVNGHLRAASALVTDPEGRSGPRDTLRRRYDAETAAALLRTAGFEVEQTHGVRVVADLLPAAVLDEDPQAVLELELALSAQPPFRDIASQLHLFARRP
>NZ_LT827010.1|WP_014688711.1|1846393_1846768_+|serine-protease
MLLRICTGFVAAVVLATAAPAAAARPESRLVLTYAGETGRPAAVRLTCDPDGGEHPKAAQACAELGRVGADPRRLKPADRLCFMLYQPVTAQLRGTWRGRPVKWTQRFGNGCEMTRATGVLFAF
>NZ_LT827010.1|WP_014688710.1|1842946_1846351_+|error-prone-DNA-polymerase
MSFHNPARPWADLVRDLDGRRNGGADRGGDGPKPAGKPGLWAAPGPEQVADPLVVDGDGGDAPAWTRKREPYRAAPGLVRSDAEVAYAELHCHTNFSFLDGASHPEELAEEAARLGLTGLAVTDHDGFYGVVRFSQAARELRLPTIFGAELSLGLTRPQNGEPDPEGTHLLALANGHDGYARLARVISQAQIRGGEKGKPEYESLEQIAEILHDHVLVLTGCRKGTVRQALATEGMDAAAWELDRLADLFGRSNVAVELTDHGHPYDGDFNDALCTLARERRLEVVATGNVHYATPARRRLATALAAVRARRGLDEMDGWLPAAGTAHLRSGAEMARRFRDYPGAVANAAMYGEGLSFDLNLVAPRLPDYDVPPGHTEMSWLRELTMRGARVRYGEHHPKAYAQLEKELRMIEELGFPGYFLVVYDIVDFCRREKIYCQGRGSAANSAVCYALWITNVDAVEYDLLFERFLAPERDGPPDIDVDIESDRREEVIQHVYQKYGREHTAQVANVISYRPRSAVRDMARAFGFSAGQQDAWSKQIDRWGDVATADSDIPEMVVDYANAVQNFPRHLGIHSGGMVICDRPIIEVCPVEWGRMPGRSVLQWDKDDCAAVDLVKFDLLGLGMLSALHYAYDMIEDELDIGTMRLDDAEVYTMLCRADSVGVFQVESRAQMATLPRLKPTRFYDLVIEVALIRPGPIQGGSVHPYIRRKNGLEKPDVPHRLMENALRKTLGVPLFQEQLMQLAIDVAGFDPAEADQLRRAMGSKRSVEKMERIKRRLYEGMAGNGITGELADDLFHKLSAFASYGFPESHAMSFAYLVYASAWLKRYHPAAFCAALLNAQPMGFYSPQTLVDDARRHGVEVRRPDINRSDAMATLETTPDTRRKAGVGEAPQVWGLGGPAVRQGLRSVRTIGADLAELIENERREHGPYRSMTDLARRTGCSIANLEALATADAFASFGLSRREALWAAGAAAQDKPDRLPGTVTGTEAPTLPGMSEVDLLVADVWATGLSPDTHPARFLREQLTGAGALSIADLGTVAAGSRVRVGGIVTHRQRPATAGGVTFVNLEDETGMLNVTCSPGLWLRYRRVARSSAALLVRGRLEKVEGVLNLVADRLDALHPPVTPASRDFR
>NZ_LT827010.1|WP_043513738.1|1841227_1842934_+|DNA-polymerase-Y-family-protein
MVWCPDWPVVAAEIELGVPGDGAVAVMANNRVLACSEAARRESVRRGLRRRDAQGRCPHLIVVEHDPGRDARTFEAVVAAVEEVAAGVEVVRPGACALAARGPARYYGGEEAAAERIVEHVAQTCAVESQVGIAGGVFAAGIAARGGQIVAVGGTAGFLAGMPVDALDRPDLADLLRRLGAKTLGEFAALPAGDVLTRFGFDGALAHRLARGGDHRPLAVRQPPVDLAVTETYDEPLDRVDTAAFAGRVLAERLHERLAGHGLACTRLGVEAVTADGQELHRVWRHDGLLGAAAIADRVRWQLDGWLTGGRRSGPARPTAGLVRLSLIPDGLLAHAGLQPGLWGDAGAERDRAHRAFSRVQGLLGPESVVTPVIGGGRSGSDQVRLVPWGDERTPARPAAVHADPIPGLVTVPVLDRAIAPDLPGRENGGTAPRKGAAAERGAAGAADGVRRNRGEGVGLPPWPGRLPRPSPAMVLPEPLPAVVHDELGLPVGVSARLELTGTPASLAVGRSAPLPITGWAGPWPVDERWWAPEEARRRARFQMSLADGRALLLSLAAGQWVVEAIYD
>NZ_LT827010.1|WP_043513734.1|1838801_1839245_+|hypothetical-protein
MGSARAEMPTVPAHMLPQRTPAQLLAIARQGLAEAAHTAPDGLRYAAAHLAALRAAAALLAARARPGAPGRRTKATSVWSLLVMVAPEFGEWAGYFALGASKRAAAEAGIPQVVSAREADDLLRAAEQFVTVAESSLGFSYQPPLAA
>NZ_LT827010.1|WP_014688705.1|1836504_1837563_+|helix-turn-helix-transcriptional-regulator
MGWWQIDADTLAGSRFVLSPLAETTAGLMRLRWDSAEHPADRPWLRAHRPAYRARLAADPITARLVDAALRPHWIADFMAPPPEIAERSFAAEVAVIRATVPAAARQHIAEGLAGGLPVGLGREDPGVRASAGLDREDSGTRSLAGLPAELDRDDLGERMAGLLTWLWQTAIAPDWPRRRRILEADVLARTRQLTQGGWQAALNGMRDGMRWLGGGRLQINAYDYPPRDISGAQLLFVPTTLGRGWAAWENPDPTRYALIYRASGVLAEPGRAAPGALERLLGAGRAGVLVALAQPKSTSQLVAITGLGLGSVGRHLRVLLEAGLVMRRRAGRSVLYTRTPAGESVVRAASV
>NZ_LT827010.1|WP_014688703.1|1833190_1835140_+|APC-family-permease
MSTEINVPAVVAPVRERMSQRPLSKWLLAHRVQPVGPESENPAHEQAWWKVMCLTGVDYFSTLSYLPAIAALAAGALSPLATLLIVALTLLGMLPMYRRVARESPHGQGSVAMLEHLLPFWRGKIFVLVLLGFVCTSWIITITLSAADATVHMSENPNLPSALHGHQVLITVVLLLILGFVFLLGFSEAVGVAIPLVAIFLLLNAVITAVGLADVFGTPGALSAWTDRLTEHGSGFFDVLGPAVLAFPALVLGLSGFETGVSMMPLIKAADGEARVRNTRKLLTTAAAIMSVYLIATSFVTTVLIPQKEFEAGGQANGRALAYLAHLKLGEVFGTVYDISSILILWFAGASAMAGLINIVPRYLPGYGMAPEWGRAVRPVVLVYTVISIGITIAFGADVNAQAGAYATGILAMMVSGAVAVTISAFRARHRGATIGFGVLTLVLLYALADNIIEKPDGIAISAVFIAGIILVSLISRVTRTTELRAERIEFDEPARRFIADSIRHDGELNIVANQRQDGDEAEYAVKEGEQRGMNPVPGRADILFLEVDVVDPSEFSEVLAVHGIEVGSHRILRVQSPAVPNAIAAVLLALRDATGVRPHCYFEWAEGSPLGHLFRYLLFGRGDTAPVVREILRQTEASPDKRPRVHVG
>NZ_LT827010.1|WP_014688702.1|1832301_1833117_-|SDR-family-NAD(P)-dependent-oxidoreductase
MTQTIVITGASSGVGLAAAEQLAARGDEVVLVGRDPGRLDAAVQRVREAGGGRAPRHFRADFERLDDVRELAAGLLAELPRIDVLANNAGGIIKRPRQTVDGHEATIQGNHLAPFLLTHLLRERLTGGRVVNTASAAHVQGRPGTRFTDDPKSYSPWRSYGASKAANILFAAEAARRWPDVCSVSFHPGVVRTNFGEGRLIRLFYRYAPGLVTPEAAGELLTWLCTTPAGELENGAYYVKRQVTRPAAHARDPRLAAELWDASLTATGLAG
>NZ_LT827010.1|WP_014688701.1|1831630_1832305_-|monooxygenase
MTHVALHVWRVPRSAVGSAMLRMAFARRHLAGLRFGKFLGTGTGTGFGPGDTDLTRWAAITVSDAPVRFPVWERIAVNGARIDLEPLISRGTWAGRTPFEPTGRRPDGPVLALTRARLRPARALTFWRAVPAVVREVHRAPGLLARFGVGEAPIGWQGTVTVWRDAADLVAFAYRQPEHRAAIARTPADRWYAEELFARFAVLGISGDRSVLGWTADEGERAEA
>NZ_LT827010.1|WP_014688700.1|1831055_1831634_-|GNAT-family-N-acetyltransferase
MRLVAWQPDDLLRRLDDVVGVYGEAMGYRQELLQTRRGYIGSHVRRPGFRAVATLTTEGRLMGFGYGYTSAAGQWWHDQVRFALGEDDRRQWLTDCFEVVELHVRPAAQGHGVGARQLRALLAMAKGRTVLLSTPEADEQASRAWRLYRRYGFADVLRHFYFPGDERAFAVLGRELPLAERPLEDAPGIAGA
>NZ_LT827010.1|WP_014688714.1|1849105_1849498_+|DUF3040-domain-containing-protein
MPLSEHEQRLFDQIERSLAEDPKFASAVRASDPRFHARRRLIIAAFVIVLGLALVVYGAASGTVLLGVAGFVVMLGAAAFAMQSRKRGQAPDLKSVGGTASRRTRQGRKGNGGLLDRLEDRWRQRPEGHR
>NZ_LT827010.1|WP_014688715.1|1850160_1852626_-|transglutaminase-domain-containing-protein
MTGRRRLGLVAAGATLLGSAPLATIFDTWSWLLRVVLTVVMIAGTAVLTRTLRFPSWAQALGMVAGLLITLTWIFPSGHELLVPTPATLAHFGDLIQQAGDDTRAYAVPVPDRDGLLFVATLGIGVVAIVVDLLTAVFRRPALAGLPMLAIYSIPVAVYLDSVPVTPFIIGACGYLWLLVADNVDRVRRFGRRFTGDGRDVDVWEPSPLASAGRRLGLAGVLVAVLLPLIVPTVNGGLLSQLTQGGSGAGGGLGKGGGQINLFAKLSGQLNQTTTVNLLKVRTDEKDPFYLRFGVADLLSNDGFSNQPPGGNTLKAGSLPDPHHDGATDQVAFQQHHADIEVSDLLRQSMAPMYSNPIAIKDLSGNWAYDPNQQVLYSNRSNTGKQKYSIDYLRALYTPAQLRTAPALGPDDPMRKLFTAHPDNKYVDTLVAGLVKGKTNDYDKIRAIYEFFSRKNNFNYSVSTQSTGNLSDIEAFLRNKTGYCQQYAAAMAWMVRDAGIPSRVAFGFTRGTPQDNGAYVITNRNAHAWTEVYLQGFGWVPFDATPAGSVAGASRSNWAPDTDRTATPTASATTAPVAGASASAAAAGTGKRPNRADDGSDLATGGTFESDQQSWTGLIVGAVVATMIALLLVPALRRVLLRRQRHAATVGPPPATSVDPGIAGPSGAVTGIEVSPGSAQARADAHAAWDELIDTMVDFQFAVDPTETPRLTAQRLVKEALLEADAAGAAELLGTAEERARYARQPMQGAELTTALRRVRAGLAHSTTGWVRLRAALFPPSILLSWRLGLAEAGTRTMEAAASTGDFLTRFNPRRLLPRGR
>NZ_LT827010.1|WP_043511039.1|1852622_1853921_-|DUF58-domain-containing-protein
MREALRGLTTRGRSFLAAAIAAGISALILGERDLLRVAVLLAALPLLAAAYVGRSRYKLACTRSLEPGRAPVGSSARVILRLQNLSRLPTGTMLLEDRLPYALGSRPRVVLERLGAQQASSVAYTVRADVRGRYPIGPLVIRLTDPFGLCELTRSFPSVDQLTVIPQVTPLPRVRLAGEYAGTGDSRARSVAVHGEDDAATREYRRGDDLRRVHWRSTARTGELMVRREEQPWESRATVVLDTRAIAHRGEGPTASFEWAVSAAASIAAHLREAGYKVRLVTGDGSDLDGSEPGGDGLILDALADVKLAAAGDLALLVEQVRRRSDGGLVIGLFGTLTTAEAQLLGQLRGNGATCIGFAIDSDTWVPMTAGDRQESDREHAAASLALVRGGWRSVPVTHGDTLPALWPTVGRGSQGFAYRAAMAETVSGVTR
>NZ_LT827010.1|WP_014688717.1|1853923_1854961_-|MoxR-family-ATPase
MTTPTWGEPTGPLSNAEFRTATQAIMTNIEQVIEGKSATVRLALAVLLAEGHLLIEDVPGVGKTKLAKALARSIDCSVRRIQFTPDLLPSDVTGVSVYNQETRDFEFKPGAVFANLVVGDEINRASPKTQSALLECMEERQVTVDGTTYELQAPFMVVATQNPIEMEGTYPLPEAQRDRFTARIAMGYPDPRAELAMLGLHGDHDPLNDIHAVADAALVRRLIDTARAVHAADAVQQYAIALVTATREAPEIRLGASPRSTLQLLRTAKAVAALEGRDYVLPDDLQALAVPVLAHRLIPTADAQLNRRTTDTIVSEIVHRLPIPVANRNPYDTRTGGTQYESRGR
>NZ_LT827010.1|WP_014688718.1|1855371_1858158_+|leucine--tRNA-ligase
MSETDNPFRYTAALAGEIELRWQRYWAENGTFHAPNPTGELADPGHPRAGAPKLHVQDMFPYPSGAGLHVGHPLGYIGTDCYTRFQRMAGYNVLHPMGFDAFGLPAEQYAVQTGTHPAVTTAANVERYRQQLRRLGLAYDERRSFSTTDPEYYRWTQWIFLQVFNSWFDPEQGRARPIDELIASYEAGERGAAWATLSPAERRKVIDGHRLAYVSEAPVNWCPGLGTVLANEEVTPDGRSERGNYPVFQRSLKQWMMRITAYGDRLVDDLDALDWPEPVKLMQRNWIGRSQGAHVDFAVDADRITVFTTRPDTLFGATYMVLAPEHALVSKIVPAAWPAGTKEAWKVAGTPAEAVEAYRVTAAAKTEEERTADGKVKTGVFTGAYAVNPVNGASIPVFIADYVLAGYGTGAIMAVPGHDQRDFEFATVFELPVVRTIATPEGCEGAYVGDGEVINSEFLNGLNKDEAKAAMIAWLEERGKGAGATTYRLRDWLFSRQRYWGEPFPIVYDETGLPIALPESMLPVELPDVDDFSPRTFDPDDADTEPETPLSRKKEWVQVELDLGDGPRMYTRETNTMPQWAGSCWYELRYLDPHNDHALVDPANEAYWMGPQRPGDPGGVDLYVGGVEHAVLHLLYARFWHKVLFDLGHVSSFEPFRKLFNQGYIQAYAFRDARGVIVPAEEVVERDGKWYHGDQEVAREYGKMGKSLKNVVTPDEMCDQYGADTFRVYEMAMGPLDVSRPWETRAVVGSQRFLQRVWRLVVDEETGAIRVTDAELDPKSRKVLHRVIAGVREDMAELRFNTAIAKLIELTNTLTPLATVSREAVEPLVLMLSPFAPHLAEELWGRLGHAGTLAYADFPQADPAQLVADSITYPVQVNGKVRGRVEVAPDTPEAEVRAQALAAVAEALGGKEPKKVIVVKGRLVSVVV
>NZ_LT827010.1|WP_014688719.1|1858316_1859030_-|TVP38/TMEM64-family-protein
MTDTPDHHTSVPSRRKRLVRLGLLAVVIGALAAASALLPLRDIGDAVVALGPGAAVAVAVLGGLLLSALVPRTAVTVACGALLGAAIGAVAALAAAVIAAAATYYLGRWAGRGVLQARAGGRLARLDGWLNRRGLAAVLLVRFLPLAPFGLIGYAYGTTSVCRKRYLLGTTIAAIPSTVTYAVIGAAVASPGRMNAITIAPAVVSFILSTAIVLRWRHTARRDAATAPSTADSAVRA
>NZ_LT827010.1|WP_014688720.1|1859091_1859805_-|glutamine-amidotransferase
MNDSTLRIVWIYPDLLSTYGDRGNLLILAHRAAARGIPVETYEVRSDMPMPTTADIYLIGGGEDGPQALAAQRLIADGGLHRAVSQGASVLAICAGYQLFGHSFFAKGTKCAGLGLLDITSDRGESRAVGELRGDIDPRLGLPPLTGFENHGGRTHLGAHAAPLARVTGGIGNDGQTEGAWAGKIIGTYSHGPALSRNPALADLLLRWSTGADRLAPLDDSWADRLRGERLAAASPA
>NZ_LT827010.1|WP_014688721.1|1859820_1861041_-|DUF1727-domain-containing-protein
MPLRAIVATTASKTAAALSRAAGRGDGSVIGGWIGLKIDPDLLAHLSSGRAVALVSGTNGKTTTTRLTAAAVGVLGRVATNSYGANMPTGHTSALAKEGHTPFAVLEVDEHYLAQVIDATRPKVVALLNLSRDQLDRAKEVAMMAQLWKTALAGHPEIRVVANADDPMVVWAAAGSPQSIWFSAGQRWHDDSFVCPESGHPIERANGDWWCTGCPLRRPTPQWVVEEDGVIDPRGDWHLVKLQLPGKVNLGNAATALAVAGEFGVRPIEALPRLSRVTSIAGRYAQVDRDGRNIRLLLAKNPASWLEAFDMADQAPTLLSINARDPDGLDTSWLWDVDFAPLRDRPVLITGDRAFDLAVRLQVNQVPFRHVHTFDEAVAQVPPGRLEVIANYTAFQDIRAVLDRVN
>NZ_LT827010.1|WP_014688722.1|1861644_1862442_+|C40-family-peptidase
MSGAGTAALSLGLCLCAGQLIGASPAVAAEATPVTTAANTVRAVAPAAAKTLVQPRLTTTTTARRITAGSVLKVTAKVINPKTGKIAKGTIRLQGYRGGKWQTWATKSSTGAVTFTTGPKSSIYIRTLFTGTGYAQTSSSRMLITVRANGGARVLAEAKKHVGALYKFAAAGPKRFDCSGFTLYVYKVAAGRSLPHKADAQQRYGSAVSKSQAQPGDLIIFRSGSYGYHAGIYAGGGYMYDSPHTGARVGKHKMYGSNYVVRRIA
>NZ_LT827010.1|WP_014688723.1|1863276_1863708_+|division/cell-wall-cluster-transcriptional-repressor-MraZ
MFLGTHTPRLDEKGRLILPAKFRDELAGGVVITKGQERCLYVFPMPEFQRIAGQLREAPVTNKAARAYSRVFFASAHDEVPDKQGRVTIPTHLREYASLGRDLVVIGASTRVEIWDRQSWDDYLSASEEDFADIQEGVLPGGL

Crispr_ID: NZ_LT827010_6

• CRISPR_ID: NZ_LT827010_6
• CRISPR_location: 2214130-2214211
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_6

Consensus_repeat	Method
GCCGTGATCGATGCGCTGCGGGGCTGAA	CRISPRCasFinder

spacers of NZ_LT827010_6

>6.1|2214158|26|NZ_LT827010|CRISPRCasFinder
GCGCTGCCCGTCCGGCGCCTGTCGCT

CRISPR arrays and Neighbor proteins around NZ_LT827010_6

CRISPR arrays

The CRISPR arrays of NZ_LT827010_6

>merge|NZ_LT827010|6|2214130-2214211|CRISPRCasFinder
GCCGTGATCGATGCGCTGCGGGGCTGAAGCGCTGCCCGTCCGGCGCCTGTCGCTGCCGTGATCGATGCGCTGCGGGGCTGAA

>NZ_LT827010|6|5|2214130-2214211|CRISPRCasFinder
GCCGTGATCGATGCGCTGCGGGGCTGAA	GCGCTGCCCGTCCGGCGCCTGTCGCT
GCCGTGATCGATGCGCTGCGGGGCTGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014689032.1|2203377_2203983_+|DUF998-domain-containing-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689046.1|2221820_2222423_+|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|235546
NZ_LT827010.1|WP_014689031.1|2203016_2203361_+|TrmB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224296
NZ_LT827010.1|WP_099343725.1|2214541_2214928_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689044.1|2219332_2220433_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NZ_LT827010.1|WP_014689033.1|2204044_2204506_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_157432769.1|2202063_2202219_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689043.1|2217841_2219017_-|homogentisate-1,2-dioxygenase	unknown	unknown	gnl|CDD|226039
NZ_LT827010.1|WP_099344024.1|2216864_2217647_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689038.1|2212515_2213055_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NZ_LT827010.1|WP_014689045.1|2220383_2221580_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|180937
NZ_LT827010.1|WP_099344021.1|2205883_2206660_-|M15-family-metallopeptidase	unknown	unknown	gnl|CDD|379247
NZ_LT827010.1|WP_043511114.1|2204598_2205639_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_099344023.1|2212210_2212501_+|DUF2752-domain-containing-protein	unknown	unknown	gnl|CDD|378499
NZ_LT827010.1|WP_099344022.1|2206936_2212006_+|diguanylate-cyclase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_014689049.1|2223979_2224477_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689048.1|2223179_2223983_+|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl|CDD|274287
NZ_LT827010.1|WP_157432770.1|2202217_2202802_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
NZ_LT827010.1|WP_014689047.1|2222459_2222936_-|DUF1707-domain-containing-protein	unknown	unknown	gnl|CDD|377959
NZ_LT827010.1|WP_014689041.1|2215596_2216868_-|fumarylacetoacetase	unknown	unknown	gnl|CDD|215461

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014689046.1|2221820_2222423_+|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	1.69913e-09
NZ_LT827010.1|WP_014689047.1|2222459_2222936_-|DUF1707-domain-containing-protein	gnl|CDD|377959	pfam08044, DUF1707, Domain of unknown function (DUF1707). This domain is found in a variety of Actinomycetales proteins. All of the proteins containing this domain are hypothetical and probably membrane bound or associated. Currently, it is unclear to the function of this domain.	5.81763e-18
NZ_LT827010.1|WP_014689031.1|2203016_2203361_+|TrmB-family-transcriptional-regulator	gnl|CDD|224296	COG1378, COG1378, Predicted transcriptional regulators [Transcription].	3.35528e-27
NZ_LT827010.1|WP_014689044.1|2219332_2220433_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	1.13364e-53
NZ_LT827010.1|WP_099344021.1|2205883_2206660_-|M15-family-metallopeptidase	gnl|CDD|379247	pfam13539, Peptidase_M15_4, D-alanyl-D-alanine carboxypeptidase. This family resembles VanY, pfam02557, which is part of the peptidase M15 family.	3.92909e-19
NZ_LT827010.1|WP_014689043.1|2217841_2219017_-|homogentisate-1,2-dioxygenase	gnl|CDD|226039	COG3508, HmgA, Homogentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	6.20094e-66
NZ_LT827010.1|WP_014689038.1|2212515_2213055_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	6.03121e-19
NZ_LT827010.1|WP_014689045.1|2220383_2221580_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|180937	PRK07337, PRK07337, pyridoxal phosphate-dependent aminotransferase.	6.13684e-148
NZ_LT827010.1|WP_099344023.1|2212210_2212501_+|DUF2752-domain-containing-protein	gnl|CDD|378499	pfam10825, DUF2752, Protein of unknown function (DUF2752). This family is conserved in bacteria. Many members are annotated as being putative membrane proteins.	2.46577e-12
NZ_LT827010.1|WP_099344022.1|2206936_2212006_+|diguanylate-cyclase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.91062e-75
NZ_LT827010.1|WP_014689048.1|2223179_2223983_+|polysaccharide-deacetylase-family-protein	gnl|CDD|274287	TIGR02764, Probable_polysaccharide_deacetylase_PdaB, polysaccharide deacetylase family sporulation protein PdaB. This model describes the YbaN protein family, also called PdaB and SpoVIE, of Gram-positive bacteria. Although ybaN null mutants have only a mild sporulation defect, ybaN/ytrI double mutants show drastically reducted sporulation efficiencies. This synthetic defect suggests the role of this sigmaE-controlled gene in sporulation had been masked by functional redundancy. Members of this family are homologous to a characterized polysaccharide deacetylase; the exact function this protein family is unknown. [Cellular processes, Sporulation and germination].	1.2372e-48
NZ_LT827010.1|WP_157432770.1|2202217_2202802_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	3.95784e-06
NZ_LT827010.1|WP_014689041.1|2215596_2216868_-|fumarylacetoacetase	gnl|CDD|215461	PLN02856, PLN02856, fumarylacetoacetase.	4.79286e-142

Protein sequences

>NZ_LT827010.1|WP_014689038.1|2212515_2213055_+|RDD-family-protein
MSYPPPNDPYGQPQQQAYGQPIPQQPYGGQQPYGAPAPGYGPAVTYASWGARVGAYLVDMLVILPFAIVALFFRPTVDPVTLQTHFSPMYFIILLLAVVVSFYNRVFLDGKGQSWGKKALGIRLVDAATGQPIGAGKAFLRGVAHFVDFIICYVGFLFPLWDEKKQTIADKIVGTVVVK
>NZ_LT827010.1|WP_099344023.1|2212210_2212501_+|DUF2752-domain-containing-protein
MRTLTGIPCPGCGLTTAAVALVRGHVGAALQANPVIFGLAALAVAVGPLVALRAAGVLEAPQPWSPTGRRRMGRLAGLLAAASWLFQLHRLGVSWA
>NZ_LT827010.1|WP_099344022.1|2206936_2212006_+|diguanylate-cyclase
MVHHVRRGEHDYALKRPLADAGELPELRTAFQREAALLACIDDPGVVGVHAVGEIDGVPGLVLEHLSGGALSDLLVYGILSQERCVELAAQLTRGLAAAHRVGLVHRDIKPDNIMIAGDGRAKLIDFGLAQLGRDTDADSDQAVGTFLYTSPEQSGMLRRPVDGRSDLYSLGVVLFECLTGRLPFEADDVGELLRLHLAAPVPDVREKRPDVDPALAAVVHRLLAKDPDDRYPDAAGLLSALRHCPGGASAEEPAASRWPMCGRDAEADRLARRWERARAGLGGVVLIHGAAGSGRTRLAEHAAGLASVSAMPVLWGTCRPDEPAPLAVLREAVQASMARVQRLADEPRAAAEKNIAEAAAAAGVAQVIKIFGDLGLLDVSGQPAAGDEHVFAAGAAFLGDLARRADGMLLVIDDAHLLDNATRQLLAALAPDLPSLPLLVLMTDTGDGAADLGVPGTLELTCTPLPPPVVGEVVASRLPGAAVPAELARHVTVRTDGTPLAVVSYLMRLLDAGLLGPLWGTWHLDTVGADALPSASGIRDLLAARLAGLSEPVLDVLTTAAVAGVRFRPEGLPGDGERTALEAGLERHVLEVRAGGWYAFVHPQLRDTLLERLGPDELRQRHAAAAAALERLPEELRDEAHAYAVARHYQRAGDAAPIADRRRTAAAAGLRALADQAPEEAVGYLVEAIDGDPAPAAAMLHSLAEAYLRAGRFPQAEATLDRALAVEPDRVARARMHLTRIELAHTIWDDTRALEAARDALTELGRPLPRHPLLLILSTLAYAFAGAVVRRTKIGFGRAEGQRREVLAALTAVLDAGGYAAIIGLRLREAGILGMRAMYAVNRLGPSPEYARVYALVGYVSSLIRLRSTGQRCQRRAMRIATDLGDPVLIAYVDWINGCSMLLGGYDDGSTWEKAITRNARWYEPAQLLPGYASQGLRLLLRGYPADAEREYERGLRGVADPALTYGTSLSMLGAMVPAYQGRFGEAAAAVKRLRDAIPPGTGTRVQHANILVAAAAVLLEQGEIGESFDEVMAEFRGLGLRTRDLMVQHKWILAFAAHARLIRLRYSSDEDRPARLAEAVTAIRELGRAGGSPLIKLSYRLSQASLAQMSGDQERGLKLADEAEKTARALDAPMAHYEICKIRARALRALGLNHEADRQARSALALATFYGWEQRRRQTRTEFGVDEGASTHRRTVAERRGPATGRNRRLEALQQVSTAAATVLDPQQLAQVALDETLRILGAERALFFLLDEAGEPVRFAGRDAAGELTDTMEYGATLVRRVAETGEAVVVTGTEQGAALGSRSAVAHGLRSILVAPVQFKGRLIGVVYLDSRLARGIFTDDDVDVLTAVSSHVAISLETARAAQLHLAVQAAQQQQALAETLRASLAELTSILEPDRLLRRLSGTLQSTLGAGSSCLVSPDGEVLEPAEIAGGRLTPDEVALVGGLTEPALLDPAGTGGLRERLLAGDPVALAVPLDGRDGRAGTVLLGGAALDDTSRQVAAALATQGMTAYDNARLFSRVQELATTDELTGQHNRRHFYAVAGALVQAAARNGRPLAAAMLDIDKFKSVNDTYGHGVGDEVIRTVARRIRAVLRHSDVLGRYGGEEFAIVLPDHEGEAMELAERVRMAVGGEPVATQAGPLPVTISIGLTRLGDDDTALDDLLARADHALYRAKEAGRNRVMAD
>NZ_LT827010.1|WP_099344021.1|2205883_2206660_-|M15-family-metallopeptidase
MTLPAAASTGSAVAAPAGPPRTAVTHPAAHIVRPGDTLPAIAARYGLKARQLQRWNDLPADFVPHPDSALRLSASYRPRPPWHTRVEPVTTPTAPNCPVPATALRRVWVTYEDFNGDPHDGSLIVNESIVPATQNAFALLYAWHFPIMAMEPLAENMPDLTDRAALTSGYECRNIAGTTRWSQHAYGLAIDVNPRQNPMIRGDYLDPPNSAPWIPRGPYLPGMIHPGGAELAFTSSGFHWGGRWHSLKDYMHFSPNNH
>NZ_LT827010.1|WP_043511114.1|2204598_2205639_+|hypothetical-protein
MISTEHRGRRAAGSLKTWAAGAVGVTLAVAVTPHAALASASPDLRAESTQLTDVVQAGSTIDLPVIVDNVARAGEEGTTAHGVSISIMAGADSFVTRHDNCWYGAYSTTCRFPGVVVAPGDRYALSPETPLAYRVAPDTPELENARVLYSVHAMSSEDDQPPWDTRQGDGPSLVLVAGPGAKPADDRNNAGTITFRTGPNPTDIVAVGTQVSATGGESVPIAFGVRNDGPAFIDPTSGRAASNGEPVWVDFAAPSGTEVESIDSRCAPFVDGAVDRSRAGAAGFARYECGLGVIDLDGYPVGWSELWSGTLKVTGTVSGPGTVTAHISQAEGDPANDTAPIEITQS
>NZ_LT827010.1|WP_014689033.1|2204044_2204506_+|hypothetical-protein
MSYAVDFTTVSTTGLESSPVADALAGLRANEARYFKNKYDHVFTVEPATEATATVDWVSHILKAERGIVIASPPLEATRFQVENIKMAYVFYRSGLSINVMYTVDEGGKRAVGFKLSDGMDIPEELGAFKFARQKSKLAGTIRGSYFVIKNEY
>NZ_LT827010.1|WP_014689032.1|2203377_2203983_+|DUF998-domain-containing-protein
MSANLLALIAVILLLTYFAILVALHVRDTRHHPLRDAVSDYGVGPTAGRFRIAVIANSLGILAMTGALADELGLLGFTHSDYVILLLIPITRLALAFFPAGMDSTRTTWTGRIHLILAILSFTFVYLSVAQLTTPLTSFTSDTVGLLLLTLRWLAAFGLAAVVITMLAPALRPFFGLAERIYLATTNLWFLVVALFLTFHR
>NZ_LT827010.1|WP_014689031.1|2203016_2203361_+|TrmB-family-transcriptional-regulator
MPTQRLVAHLRELGFSPYEARCYAGLLGAGPLTGYAVAKLTGVPQPKVYETLRRLVARGAAEQAPGPPIRFTAVDPQDLLNRLAAAHAAQIAAVRAAAEQLLALKIGSRRSEHY
>NZ_LT827010.1|WP_157432770.1|2202217_2202802_+|hypothetical-protein
MPAHPGPRAAVAPPPVNPISPPPGQTATPAQQPVAPPQQPVAPPQKPTVPPPADNPPAKPADPTVRAAFMKGDAGPVLIEVINPAGDRAARDIVGQVAQAPRRCPSYDEGKPGTPDALHMVTMPLSVPKLGNRSAGVHFEVDMTSPRVTVHGKMIAVSVRGVVVTVLLANLEPPDQHELETITRTAVRKVQHQR
>NZ_LT827010.1|WP_157432769.1|2202063_2202219_-|hypothetical-protein
MPAPGPTGGLVPVGGVSAGLVSPGLVSAGLVPQSPTLEPVSLNALSASGTG
>NZ_LT827010.1|WP_099343725.1|2214541_2214928_+|hypothetical-protein
MRSMVLAGLIPAVLVPGAAQASPCPTTDVLGTYAFGRAATIGAAGETAGVWTVAGTRSGIAGDDLIVTYTPRYTAAATETAVYTALFNQVARPDVECDRVGADGVAKHVWVTYRCRTGVAPNYTLLVR
>NZ_LT827010.1|WP_014689041.1|2215596_2216868_-|fumarylacetoacetase
MTWLHLPEATGFGLTNLPYGIFSTPAGTAAGSPTAPGAAPRPADTPRPAGSAAPVPGARTGVAIGDHVLDLAGLTGDPVHATGSLNAFMAQGPDTWAALRSMITTWLTDPAHQERVTPHLVPRDGVTMHLPFEVADYVDFYSSRDHAENLGRMFRPGSPALTPNWTHLPIGYHGRAGTVQLSGTPVTRPQGQSLVDGTPALGPSRRLDIEAEVGFVVGTPSPLGTPVPLSDFPAHVFGVCLVNDWSARDLQSWEYVPLGPFLGKSFLTSISPWVVPLAALSAARVKAPTRDEPLLPYLDDSAEPWGLDLTLEVRLNGHVISRPPFAGMYWTPAQQLAHMTINGASLRTGDLYASGTISGPTRDQRGSLIELSWNASDPLTLPDGSTRSFLEDGDEITITATAPSPDGSRLSFGTVTGRVLPAR
>NZ_LT827010.1|WP_099344024.1|2216864_2217647_-|hypothetical-protein
MFPPGNAPMAAAVPAFLDRLATPHAPLVGPFIAPAARLAEVAAHLRPAGPPLDIALIAAPADLPAAVDKIDKTPGMRLVAVEAPVAVDAAHTRSAVRVIADSLPPGLPAAVEVPRTAARDEVLDALAGTRCRAKLRTGGVRADLFPPVEELAATIRACITRSVAFKCTAGLHHAVRHTDPATGFDHHGFLNVLLAAAHPDAAETHLARTDAARIAADLRAWSPATAVRARAAFTGFGTCDLADPVNDLAHLGLLPERYPA
>NZ_LT827010.1|WP_014689043.1|2217841_2219017_-|homogentisate-1,2-dioxygenase
MTFYRQVGSIPPKRHTQHRRPDGGLYAEELVGEEGFSSDSALLYHRGIPSAIVDARPWQLPDQSLTPNTPLVPRHLRLHDLEYKDADPVTGRRLVLGNADVRITYAVSSEASPYYKNAIGDECVYVERGSATVETVFGALTVGRGDYVIIPRTTVHRWVPDGGEPLRTYAIEASSHIAPPARYLSRYGQFLEHAPYCERDLRGPVEPMLAEGTDVEVFVKHRGGGSIHVVPEHPFDVVGWDGCLYPYAFNIADFEPITGRVHQPPPVHQVFAGQNFVICNFVPRKVDYHPLAVPVPYYHSNVDSDEVMFYVDGDYEARKGSGIGKGSISLHPGGHSHGPQPGAVERSLGAEFFDELAVMVDTFRPLDLGEAGLASDDGRYAWSWSGRGPSA
>NZ_LT827010.1|WP_014689044.1|2219332_2220433_+|AI-2E-family-transporter
MASTLSTSKTRAAMRDAARVSAQTLLILLLLYVFLELLGMAWSVLWPLVVALLLTTLTWPPVRWLRGRGWPPALAASLVTILFLALVAGIVVLIAVPVSAQSGKLGQGVVDGIQTVRDWASGPPLRISDDQVNSGLNSAVDKLQASVGSIANATLAGVSTIVNGLVTTILALFLMFFFLKDGPRFLPWLSRQLPGRLGDDVPAIAGRSWNTLSAFVRSQAFVGLLDAVFIGLGLWIVGVPLVLPLAVLTFVTAFVPIVGAVFAGLVAVLIALVFNGWVKALIVLGIILLVQQLEGNVFQPMIQSRGLGLHAAVVLLAVTLGGNLAGIVGSLLAVPVAAIVSVIWNYLREQLSDPEPIPAEVAEQTD
>NZ_LT827010.1|WP_014689045.1|2220383_2221580_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MRLSQRALSAEPFHAMAFGRRAGELEAAGHDVVRLGLGEPDFGAPPAVREAMRRVMDGRPLPYTPAFGLPALRAAIAGFYRERHGVQVDPARIAVTPGASGALLLVAAATTDPGDEVIVADPSYPCNRQLVETFGGTVVTAATTPESRYQLDTAAVDAVWSERTRAVMVASPANPTGTSLPFADLVEVCARARARDAWRIVDEIYLDLADPAADGTPPRTILSADPDALVINSFSKYFGMTGWRLGWCVLPEALVPAAERLAMNYFLCASTPAQIAALECFTPESLAVCEQRRRELLARRAIALEGLAGIGLPVPVPPDGAFYVYFDVSGTGLGAWEFCRRALEEAFVSVTPGRDFAVATAESHVRLSYAASREALREGLARLSRFVQQLRRESAPGR
>NZ_LT827010.1|WP_014689046.1|2221820_2222423_+|SDR-family-NAD(P)-dependent-oxidoreductase
MRVAGRTLVVTGAGDAIGRAVALEAARRGARVAAVDTDPAELRETARQVVAPLLLSTHLLSPGPAPTGIEALPRAVLDRWGQVDAVIHCAPDGTPVVARAFLPTLRLRPEAHLVHVADSRSPAADRAAAKAFAHELRAETTLFVAMVFPTDPRRPYQAARDILDGMERNAYPARIGSDRRIRDVRGVAALLMARLRELVA
>NZ_LT827010.1|WP_014689047.1|2222459_2222936_-|DUF1707-domain-containing-protein
MYPSPHVRVSDSDREAVVARLSTATAEGRLTIEEFSERSRSAYAARTWGELSRVLYDLPGDELVATPAAAAAGSRLPLLALIAGALPLPLALCAQVVLPAPICAVTAVVLGIMALRGPADTVRHGRRMAIGGIALGGLGVLAIVTGIAQFLFGGSLDA
>NZ_LT827010.1|WP_014689048.1|2223179_2223983_+|polysaccharide-deacetylase-family-protein
MLSRRALLRTGLAGLAGVAVGAAGAREIPHWLGWDRPPVLGGYAAAADQLDGLHQPGVAVRYFVDTSEPLVAFTFDDGPAPHWTPMVLDALDAAGVPATFFMVGSRLERHADLVRGRMDRHAIGNHTWAHDDLATLDLGAVTRNLQRTEQEIRRHFDRQVTLLRPPFGHIGGSTMLAADQLGYDVVLWSKAMREQLFHDDPMGQARDIVDSVRPGSIILAHDEGDDKRLVTVHGLAAMFDGLRKRGFRMVTVPDLIAAGTSPSQGSH
>NZ_LT827010.1|WP_014689049.1|2223979_2224477_-|hypothetical-protein
MTAEGAVPDGAAVRFRDPAIRLPELAADEIDVVCPHCGCRAVVSADPVQGAVAMHSPRRFVCTRCVTVAQWPPKVGVSRWGGPIDPYFHLPLWFQARCCGGRTLWAFNEAHLTLLADYVGAKLRERHPREPGLTMVARLPGWLKAADNRTEVLRTIARLRHRPTR

Crispr_ID: NZ_LT827010_7

• CRISPR_ID: NZ_LT827010_7
• CRISPR_location: 2648287-2648475
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT827010_7

Consensus_repeat	Method
CCGGGTCGGCGGCGGACTCGCGCCCGA	CRISPRCasFinder

spacers of NZ_LT827010_7

>7.1|2648314|63|NZ_LT827010|CRISPRCasFinder
AGCCCGGTCCTGCCGCTTCGGTTCCCACCAAGCCCGCCCCAGCCGGCTCGGCGGAGTCGGCTT
>7.2|2648404|45|NZ_LT827010|CRISPRCasFinder
GGCCACATTCCGAGGCGGGAGCGCATTCGCGACCGAGGCCGCATC

CRISPR arrays and Neighbor proteins around NZ_LT827010_7

CRISPR arrays

The CRISPR arrays of NZ_LT827010_7

>merge|NZ_LT827010|7|2648287-2648475|CRISPRCasFinder
CTGCGTCGTCGCCGGTGGCGAGCCCGAAGCCCGGTCCTGCCGCTTCGGTTCCCACCAAGCCCGCCCCAGCCGGCTCGGCGGAGTCGGCTTCCGGGTCGGCGGCGGACTCGCGCCCGAGGCCACATTCCGAGGCGGGAGCGCATTCGCGACCGAGGCCGCATCCCGGGTCGGCGGCGGACTCGCGGCCGA

>NZ_LT827010|7|6|2648287-2648475|CRISPRCasFinder
CTGCGTCGTCGCCGGTGGCGAGCCCGA	AGCCCGGTCCTGCCGCTTCGGTTCCCACCAAGCCCGCCCCAGCCGGCTCGGCGGAGTCGGCTT
CCGGGTCGGCGGCGGACTCGCGCCCGA	GGCCACATTCCGAGGCGGGAGCGCATTCGCGACCGAGGCCGCATC
CCGGGTCGGCGGCGGACTCGCGGCCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014689432.1|2659130_2660288_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NZ_LT827010.1|WP_014689417.1|2640851_2642003_-|L-rhamnose-isomerase	unknown	unknown	gnl|CDD|274239
NZ_LT827010.1|WP_014689427.1|2652629_2653229_-|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NZ_LT827010.1|WP_014689422.1|2647260_2647680_+|phage-holin-family-protein	unknown	unknown	gnl|CDD|377816
NZ_LT827010.1|WP_099344039.1|2639248_2640403_+|response-regulator	unknown	unknown	gnl|CDD|381113
NZ_LT827010.1|WP_014689414.1|2637859_2639050_-|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_LT827010.1|WP_014689430.1|2656177_2657512_+|aspartate-aminotransferase-family-protein	unknown	unknown	gnl|CDD|235687
NZ_LT827010.1|WP_052311562.1|2651068_2652649_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_014689413.1|2636250_2637855_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|223910
NZ_LT827010.1|WP_014689429.1|2654675_2656166_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143404
NZ_LT827010.1|WP_014689428.1|2653286_2654615_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|185378
NZ_LT827010.1|WP_080128209.1|2650143_2651070_-|inositol-monophosphatase-family-protein	unknown	unknown	gnl|CDD|334090
NZ_LT827010.1|WP_014689416.1|2640456_2640843_+|Hpt-domain-containing-protein	unknown	unknown	gnl|CDD|366732
NZ_LT827010.1|WP_014689418.1|2641999_2643031_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|119321
NZ_LT827010.1|WP_014689421.1|2645484_2646513_-|autoinducer-2-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380525
NZ_LT827010.1|WP_099344040.1|2660329_2661538_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270308
NZ_LT827010.1|WP_014689419.1|2643027_2643984_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|119321
NZ_LT827010.1|WP_014689424.1|2649161_2650022_+|DUF3618-domain-containing-protein	unknown	unknown	gnl|CDD|378834
NZ_LT827010.1|WP_014689420.1|2643980_2645480_-|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_LT827010.1|WP_043513989.1|2657643_2659080_+|aminobutyraldehyde-dehydrogenase	unknown	unknown	gnl|CDD|237391

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014689432.1|2659130_2660288_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.51167e-162
NZ_LT827010.1|WP_014689417.1|2640851_2642003_-|L-rhamnose-isomerase	gnl|CDD|274239	TIGR02635, putative_xylose_isomerase, L-rhamnose isomerase, Streptomyces subtype. This clade of sequences is closely related to the L-rhamnose isomerases found in Pseudomonas stutzeri and in a number of the Rhizobiales (TIGR02629). The genes of the family represented here are found in similar genomic contexts which contain genes apparently involved in rhamnose catabolism such as rhamnulose-1-phosphate aldolase (TIGR02632), sugar kinases, and sugar transporters. [Energy metabolism, Sugars].	0
NZ_LT827010.1|WP_014689427.1|2652629_2653229_-|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.56441e-23
NZ_LT827010.1|WP_014689422.1|2647260_2647680_+|phage-holin-family-protein	gnl|CDD|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	1.89397e-24
NZ_LT827010.1|WP_099344039.1|2639248_2640403_+|response-regulator	gnl|CDD|381113	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains. This family is composed of mostly uncharacterized response regulators with similarity to the REC domains of response regulator components of two-component systems that regulates hydrogenase activity, including HupR and HoxA. HupR is part of the HupT/HupR system that controls the synthesis of the membrane-bound [NiFe]hydrogenase, HupSL, of the photosynthetic bacterium Rhodobacter capsulatus. It contains an N-terminal REC domain, a central sigma-54 interaction domain that lacks ATPase activity, and a C-terminal DNA-binding domain. Members of this family contain a REC domain and various output domains including the cyclase homology domain (CHD) and the c-di-GMP phosphodiesterase domains, HD-GYP and EAL. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	5.13719e-43
NZ_LT827010.1|WP_014689414.1|2637859_2639050_-|GAF-domain-containing-sensor-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.56411e-42
NZ_LT827010.1|WP_014689430.1|2656177_2657512_+|aspartate-aminotransferase-family-protein	gnl|CDD|235687	PRK06062, PRK06062, hypothetical protein; Provisional.	0
NZ_LT827010.1|WP_052311562.1|2651068_2652649_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.60268e-101
NZ_LT827010.1|WP_014689413.1|2636250_2637855_-|methyl-accepting-chemotaxis-protein	gnl|CDD|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.04488e-46
NZ_LT827010.1|WP_014689429.1|2654675_2656166_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl|CDD|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NZ_LT827010.1|WP_014689428.1|2653286_2654615_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	9.63421e-73
NZ_LT827010.1|WP_080128209.1|2650143_2651070_-|inositol-monophosphatase-family-protein	gnl|CDD|334090	pfam00459, Inositol_P, Inositol monophosphatase family.	2.31779e-40
NZ_LT827010.1|WP_014689416.1|2640456_2640843_+|Hpt-domain-containing-protein	gnl|CDD|366732	pfam01627, Hpt, Hpt domain. The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. A multistep phosphorelay involving the HPt domain has been suggested for these signaling pathways. The crystal structure of the HPt domain of the anaerobic sensor kinase ArcB has been determined. The domain consists of six alpha helices containing a four-helix bundle-folding. The pattern of sequence similarity of the HPt domains of ArcB and components in other signaling systems can be interpreted in light of the three-dimensional structure and supports the conclusion that the HPt domains have a common structural motif both in prokaryotes and eukaryotes. In S. cerevisiae ypd1p this domain has been shown to contain a binding surface for Ssk1p (response regulator receiver domain containing protein pfam00072).	4.59762e-09
NZ_LT827010.1|WP_014689418.1|2641999_2643031_-|ABC-transporter-permease	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	1.39377e-56
NZ_LT827010.1|WP_014689421.1|2645484_2646513_-|autoinducer-2-ABC-transporter-substrate-binding-protein	gnl|CDD|380525	cd06302, PBP1_LsrB_Quorum_Sensing-like, periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs. Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs from other bacteria. The members of this group are homologous to a family of periplasmic pentose/hexose sugar-binding proteins that function as the primary receptors for chemotaxis and transporters of many sugar based solutes in bacteria and archaea and that are a member of the type 1 periplasmic binding protein superfamily. LsrB, which is part of the ABC transporter complex LsrABCD, binds a chemically distinct form of the AI-2 signal that lacks boron, in contrast to the Vibrio harveyi AI-2 signaling molecule that has an unusual furanosyl borate diester. Hence, many bacteria coordinate their gene expression according to the local density of their population by producing species specific AI-2. This process of quorum sensing allows LsrB to function as a periplasmic AI-2 binding protein in interspecies signaling.	3.6051e-120
NZ_LT827010.1|WP_099344040.1|2660329_2661538_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein	gnl|CDD|270308	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.66997e-93
NZ_LT827010.1|WP_014689419.1|2643027_2643984_-|ABC-transporter-permease	gnl|CDD|119321	cd06579, TM_PBP1_transp_AraH_like, Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.	5.54355e-61
NZ_LT827010.1|WP_014689424.1|2649161_2650022_+|DUF3618-domain-containing-protein	gnl|CDD|378834	pfam12277, DUF3618, Protein of unknown function (DUF3618). This domain family is found in bacteria, and is approximately 50 amino acids in length.	1.01699e-06
NZ_LT827010.1|WP_014689420.1|2643980_2645480_-|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_LT827010.1|WP_043513989.1|2657643_2659080_+|aminobutyraldehyde-dehydrogenase	gnl|CDD|237391	PRK13473, PRK13473, aminobutyraldehyde dehydrogenase.	0

Protein sequences

>NZ_LT827010.1|WP_014689422.1|2647260_2647680_+|phage-holin-family-protein
MAHTDARSEQATTAELVSRLSEQVSTLVRDELTLARMEMVEKGKRAGKGAGLLGAAGVLAMYGAGALLVAAGAALALAMPVWLAALIVTAVLFAGAGIAALVGRRQVRDALPPEPEEAMASGREDVDAFMTAARTGRSR
>NZ_LT827010.1|WP_014689421.1|2645484_2646513_-|autoinducer-2-ABC-transporter-substrate-binding-protein
MRSRLPFALALSTVAALAVSGCTKKNDTDGAPSGSGDRKTYKVAFVPKLQGVPYFEAMNAGGKAAAAALGNVEWLYQGPTQADAGAQADIVRSYIQQKVDALIVAPNDPDSMAPLLQQAKDAGIHVATADTDAPNSVREVFVNQATADGIGQGLTDALLKAMGGKGRYAIVSCGQTAENLNSWIRVQQAYTRQKYPDATIVDTVYAGEDQAKATQMATDLMNAHPDLTGLVGECTSSAPGVAQAVKDAGKIGKVFTVGLGTPQSMKPYLKDRSSSAAILWDVQQLGYLTAWAGAQIAQGKPIQATNDVSDKLPAVTYDAAGKMLLLGPALQITDQNVDQFGY
>NZ_LT827010.1|WP_014689420.1|2643980_2645480_-|sugar-ABC-transporter-ATP-binding-protein
MTTGTPRLRLSGIAKRFGAVRAIQQADLVIREGRVHALVGENGAGKSTMIKIVSGAETADAGTIEFDGEPVRIGGTNDAIALGIATVYQEPQLFGELTVAENIFLGREITRAGRIDWAAQQGRVAELLERLGLPARSANAAVNTLSVAEQQQVSIAKALATEARVLILDEPSAILTDAEIDVLFDVVRRLTAAGVAVIYISHRLDELFRIADEVTVMRDGKTIGTYDMSGLTVRRIAELMVGGVLSDERPHRVVPDGPAVLELRGLGRAGRFADVDVTVRGGEIVALYGLVGSGVSEIAAAVYGIDRITAGEIHIGGERVTPRSPAHAQRLGVALLPANRKVEGIFGVQSIAFNISAGHLRLLSRFGTLLDRGRERGVALDLIRRLSVKTPSERQPISAMSGGNAQKVVLARQLVERPRVLILAEPTQGVDVGAKEEIHRIVTELADSGTAVLVVTSDLPEALRIADRIQVVRGGTTTMSFGPDASQVDLLAAAAGGDE
>NZ_LT827010.1|WP_014689419.1|2643027_2643984_-|ABC-transporter-permease
MRNRVTGQELVLVGVIAVLWAALAVGTPAFLTAGSIQPLLVATAPTALVGVGMTIVIITGGIDVSVGGALMVCSVLTAKALVGPGVDPGVAVLLPVAVGGVLGLVNGLLIAYGRVHAIIITFGTANLFLFAGLRIFGSGTVNGIPGTLAFFGRGADGRTLGVPHAFLITVLVTGLAWWYLRHTAGGRHFFAIGGDAVAARLAGVRVQRRVLIAYVVTGLLVGLASCFVIAQGTSTLDQSVGSGRELAVIAAVVIGGTSIMGGRGSVTGTLLGALLVQSVSSGVTQLGWRSQLSDLFVGVFIIVAVGADLLRARARRSR
>NZ_LT827010.1|WP_014689418.1|2641999_2643031_-|ABC-transporter-permease
MSRVVKMLLTQRIALLAVLIVAVVVTFFIQDAGGYLTASYDFDYMSAALINAVPLAMLGLAELLVILSGRGGIDLSVGAIVSLAGMVFGFAYGHWGWPLGAAILLTAVCGALLGALNGFLVSYIGFPALIATLATYYADKSLAIVINDQQPISTTPIQHLFAISRSVELPLFGRYVPDVPLGVFTFLLPTVVAVWLLLARTAYGRRLYAIGTNDVAARWSGLPVRDTRFKAYVYAGLLAGLVAVVTVGQFASARPDAGVSGNGMALPAITIAVLGGVAITGGIGRVAGVVLATLLIVWLNAGILLAFIGNEGSQYQLFALGAVLVFAALLNGLTNRRYGGTSS
>NZ_LT827010.1|WP_014689417.1|2640851_2642003_-|L-rhamnose-isomerase
MNLDDLDGFSVEVPSWAYGNSGTRFKVFTAPGVPRDPYEKIADAAQVHRLTGLAPRVSLHIPWDRVDDWAALRAHAEGLGVRLGAVNSNLFQEDDYRLGSLCHPNPAVRDEAVGHHLRCIEIMHETGSTDLKIWLPDGLNYPGQDSLRGRQDRLADALRRIYDALGDGQRILLEYKFFEPYFYSMDIPDWGTSLLHCLALGERATVVLDTGHHAPGTNIEFIVMQLLRQGRLGAFDFNSRFYADDDLIVGSADPFQLFRIMTEIVAAGAHRPSSGVNFMLDQCHNIEEKIPGQIRSVLNVEQALAKALQVDRDALAVAQREGDVLGANEVLMAAYETDVRTALADRREARGLPRDPVKAFKISGYAVTTAAERADGAPAGWGA
>NZ_LT827010.1|WP_014689416.1|2640456_2640843_+|Hpt-domain-containing-protein
MEDERLATVRARIDAITEPDPSPAEIALVLRLLRSFAAKTPDAVDRLLDALTKDDPGLTRDEAHALKGSAANIGAAALAAVCSSVEDQARAGGVVDPAAAAGLIRTEAAGALRAVSALADEYARRCPG
>NZ_LT827010.1|WP_099344039.1|2639248_2640403_+|response-regulator
MVLVVDDEQTVLDALSLQLGREFNVLTAPDGERALKVLAEHGRAAAVISDMRMPGMNGIELLRRVQMEYPDITRVLHTGHGDMSTAVAAINSGGVYRYLPKPADTDALRDAIRASVAKHDEAIADRELLDRTLRTSVKALFGVLELSNPPAYRRAGRISTLVGELCHLLQLDGLWEIEVAAMAAQLGAVAVPAATLTKVERGLPLSADEQASVDAMPRIALRLLGDIPMMGEVLAIVRGLTGAPTPAEGRSALAEDAIAVLRTATDYEMLESRGVNAVDAITAIEEREGHYPHVVAALRRLKGVRAVKDTVKSVRVTELEVGMRLIEDVVATNGLVLIGKETVITELMLDRLTNFARAIELIETVLAAVPYRASYQPTAYAGHR
>NZ_LT827010.1|WP_014689414.1|2637859_2639050_-|GAF-domain-containing-sensor-histidine-kinase
MSAVGDAARVAAVRSYQLLDAPRPVVLDELTRLAGSVFETSMSTVTLVEADRQWFAGSTGMPSSGGPLGSSFCGVVVDQRMPLVVADALTHPVFRSWENVVGAPHIRFYAGVPLVDEDGFTLGTMCVLDDRPRDTADRRLDMLHTMAGQAAGHLSGVRNRMLLAEVGDELSRAISREEDFVATVSHELRTPVTTIQGYLELLVDNEELAPYRRMIEPIQRNGERLVRMVDHLLAGTRPVGTPLPLLRAQTDLVTVAEAAMAACRPQAAQRDVSLVLEVAGGAGPFPVPGDFTRLSQAAEHLIRNGVLFSPPGSTVRVLADEFGLSVADAGAGIPADELPHVAERFFRGRFAREQAVPGVGLGLAITQRILRAHEGTLTVMSDGSGMGTTTRMTVIS
>NZ_LT827010.1|WP_014689413.1|2636250_2637855_-|methyl-accepting-chemotaxis-protein
MRILRRLRLGGRLSVAFAVVLVLLGVAVAIGAVGLNRQSTAAADNRDLMRLQHQVDQQKYFDGDISGWQVAYAWDTRRGDPRKAVDPASENRAGFLADAQALRDLLRATDTGRMTPAERQLFDTLSATWDEYFKADSQAAALYAKGDVAGGDKQILGPGYDLYFAIVQGTDKLVAAVTGRAEQATRTAQRQAATARNALIIAFALAVVAAVLLTVVVTRSVTGPIGRLISTLQAMARGDLTVRADTDGGDEIAVMGRAVDEAITGIRGSVVEIVESGVRLTEASETMRRVSQEIDQAVAEADQQAGLAAASASGVSGNVHTVAAGTDEMGSAISEISRNAGDAAQVATDAVAAARATSATINRLGDSSAQIGDVIDVITTIAAQTNLLALNATIEAARAGEAGKGFAVVASEVKDLAQETARATEQISQQIAAIQSDTGQAVTAIDEISRIIEQISDYQTTIASAVEQQSATTAEMNRGVTEAANGASDIAGNIANVASSTAASRAAAGQAARTAHEVETLAEQLRSAVQRFRI
>NZ_LT827010.1|WP_014689424.1|2649161_2650022_+|DUF3618-domain-containing-protein
MAVQAKQGTGAKPVAGTGGKAQSSGAPRDADELRNEIEQTRAEMGETVEALVAKVDVPGRVKSAAADKVAHVKESAAELKDSAAEKAAHVKDAAIGAAGQIKDKAAKVGGAAEAKPGGGAAEAKPGGGAAEAKPGGGIAEGNLSGGGGAVAGGGLSAVKDEVREKAAQIKESAVERGSHAKEAMTQAAGELRESAASGAESVRAAAMAKLREPGAGEKTHGAGRIAEATAQTSARMGCQAADAAERASAAIGSARRRVVARPREFALLGAVLAAAAAGVALIRRSR
>NZ_LT827010.1|WP_080128209.1|2650143_2651070_-|inositol-monophosphatase-family-protein
MSLDIPSPGASATSAASAAAGRGGSAGEFIEPAVLGRGDQRRIILARPRYRSRVDHETAITAALAAATVIRDRYGRSLDRVDKGGGDFATAADLAAEQAIHDVLRAAHPGDAITGEETGASGPTGARRRWLVDPLCGTLNYAARTPLVAANVALRDGAHLTAAASADPFTGETYWTDGSSARLRHPDGTDTPLTPSGESALVDINLDPPFPTEPARIVATPGFRARFRPRVMSTTLALLWVSDGRRAAYLTYGDVSDSVHFAAGIAICEAAGCVVTATDGSPWQTGRGLLAAADPGTHRDLLALIRST
>NZ_LT827010.1|WP_052311562.1|2651068_2652649_+|serine/threonine-protein-kinase
MPDAPTLLAGRYRLGAELGRGGMGQVWLARDETLERDVAVKLLDLPEELAEGDATRRTLREARASARLSHPSVVQVYDVLSLDDRAWIVMEYVPSRSLREVIESDGPLDAYRAARIGLDLLAALEAAHRAGVQHRDVKPANVLLADDGRVLLTDFGIAAIDDDSLTSRSDVLLGSPLYMAPERARYGVSGPPADLWGLGATLYAAVEGHSPFQRASTMATLAALATEEPDPPQHAGPLTPVLDGLLRKDPDERIVAAEAERLLQRAVADLERSRSVPKPRTPVDDTVQQATDGVRGNRILLVGALIVVLLAGFAVFWFNRPSPRTTTGPAPATTAAIAVAGAEPSAAGSAGVTPSVSVSPSLSGGPSVSPSPANGRPPLPAGWKVYDDATGFSVYVPEGWTTSKSSGSSMRYWRDGKGHVLGIDQTDHPRSDPVADWKSQRDTRLRGGDFPGYDEKKLESVSYFVKAADWEWTFRKNGVQHVNNRGVVTSAHHAYGFWFQTPDADWAKYEKDVLEVVFKSFIPAKD
>NZ_LT827010.1|WP_014689427.1|2652629_2653229_-|Uma2-family-endonuclease
MSACDTLPMSQVTLPYHEGPWSEDDYLALGETDHRIELIDGSLWVSPAPNRPHQHISAFLWLALQATARTAGFQVLLTTNLRLATGRILIPDLVVDNGPPLEIVGEATDAVLVCEITSPSNATSDRILKRALYAEAGVPWYLLVEPDFSDYASLTLRLFRLTGREYVEHALAKQGETLRSRLPFPISISTDDLISPWRE
>NZ_LT827010.1|WP_014689428.1|2653286_2654615_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MFEAIFARLTDPSARGLAEALSRAIGDGAIEAGAKLPPVRTVATELRLSPSTVNAAWQLLRRAGTIRTDGRRGTVVAAPGSGGPGRYRAALRRAGGFGLDLSTGVPDPRLLPPIPALHGLSPTPTSYLDEPVLPELAALLRDRWPYPADRLAVFDGAMDAIDQVASSLLRLGDLAVVENPCFPPLLDLLEVLGVPVIGVGTDAEGMLPAQLAAALTRRPAAVFLQPRALNPTGASWSPSRATALAAVLQKTPEVYVVEDDSAGDLAAGPLSSIGVHLPRQTIHVRSFSKSHGPDLRLAAVSGPAGVLDPILERRLLGQGWTSRLLQRLLLCLLTDPASVAAVAAARDEYARRRRLVVDGLRAAGIDLPDGEGINLWLPVADEQAALLSLASAGIGAAAGTAFTVGPGSPHLRITVGLVTTDHAAVASRLAHAAHTLAPAIPR
>NZ_LT827010.1|WP_014689429.1|2654675_2656166_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MNQIAHWIGGAERAGRSGRVAPVFNPATGEQTAEVALAGTDEVAEAVAVAKEAAEAWRAASLSRRSAVLFTFRELLAGRTAELAAIVTAEHGKVLADAAGEIARGLENVEFATGIPHLMKGAFSEQAATGVDVYSIRQPLGVVAGITPFNFPVMVPLWMCATAIAAGNAFVLKPSEKDPSAALWLARLWAEAGLPAGVFTVLNGDKEAVDALLVHPDIAAVSFVGSTPIAKYIYETGTAQGKRVQALGGAKNHMIVLPDAELDAAADAAINAGYGAAGERCMAISVVVAVGDIADPLVEAIAARLPKIRVGNGADRGVDMGPLISAQHRDRVAGYIAAGEQAGATVIADGRKSAIADEDGYFLGATLLDNVTTDMTVYTDEIFGPVLSVVRVDTYAEAVRLVNENEYGNGVAIFTRDGGAARRFQFDVEAGMVGVNVPIPVPVAYYSFGGWKASLFGDSHMYGPDGIHFFTRGKVVTSRWPDPGTSAIDLGFPQTR
>NZ_LT827010.1|WP_014689430.1|2656177_2657512_+|aspartate-aminotransferase-family-protein
MSEAQVRADDRAHVFHSWSAQGLINPLPIAGASGSYFWDYDGRRYLDFSSQLVNINIGHQHPRLVAAIQEQAARLCTIQPAFANDKRGEAARLIAELAPGSLNRVFFTNGGAEANENAIRMARLHTGRHKVLATYRSYHGSTATAITATGDPRRWPNEPVAVGVVHFWGPYPFRSPFHSDSEEQESRRALQHLRDTIVFEGPGTIAAILLETVVGTNGILVPPPGYLAGVREICDEFGIVFIADEVMAGFGRCGEWFAVDHWGVVPDLITFAKGVNSGYLPLGGVVISDEIAETFRERPFPGGLTYSGHPLACASAVASIEIFKEEGIVEHARMLGTEVIAPALAELKEKHPSVGDVRGLGVFWAIELVKDADRTPLVPFNAAGAAAGPMNEVAAACKERGLWPFTHFNRVHVVPPCTTSVEEVREGLTILDEALTVADGFYGS
>NZ_LT827010.1|WP_043513989.1|2657643_2659080_+|aminobutyraldehyde-dehydrogenase
MSTELPVLRNFVNGSFTDTDQGRTSPVVDPSTGEAYALAPVSSERDVQVAVEAATAGFEVWRDTTPAERQRALLRIADAVEARAEELIEAECRNTGKPVAATRAEEMGPVLDELRFFAGAARMLEGKAAAEYLRDHTSYVRREPIGVCAQITPWNYPLVMAIWKLAPAIAAGNSVVLKPSDTTPVSTLLLAGIAAEFLPAGVLNVVCGDRDTGRALVAHPVPQLVSITGSTRAGMEVAAAAAPDLKKVHLELGGKAPVVVFDDVDIAATAAAIAGAGFFNAGQDCTAATRVLVHERIATDFTAALAEAARGTRVGAPSDTAAFFGPVNNAAQLERVAGFLDRTPAHAEVVAGGRRIGDRGYFFAPTVVAGLRQRDEMIQDEVFGPVITVQPFADEAEAVRYANDVRYGLSASVWTQNHGRAMRVSRRLDFGAVWINTHLPFVSEMPHGGYGHSGHGKDLSLYGFEEYTRIKHVMSYHG
>NZ_LT827010.1|WP_014689432.1|2659130_2660288_+|ABC-transporter-ATP-binding-protein
MTTSVPHHAAKAAPATGERTGYPAIEFAGVRKEYLSHGEAVPAVKSLDLAIGQGEFFSLLGPSGCGKTTTMRMIAGFEQPTTGTVFLDGKDVTNVAPNKRDVNMVFQSYALFPHLNVLQNVSFGLERKKVAKSEIKRRVGEILEIVSLTGMEKRQPKEMSGGQQQRVALARALVNHPRALLLDEPLGALDLKLRQQMQIELKRIQREVGITFVYVTHDQGEALTMSDRIAVMNAGLIEQLGTPREIYERPSTRFVAGFIGTSNIVDGQVARVEDGFAVLDLGSGERILAPVPGTVQAGRKLEVSVRPEKIDLHRSAPQAVTGSLLSGTVTEVVYHGTSTNYTVATSAGSDFVVFDQNAHDAEDVASRGERVFLTWAPQHSYPIGV
>NZ_LT827010.1|WP_099344040.1|2660329_2661538_+|spermidine/putrescine-ABC-transporter-substrate-binding-protein
MTQRRLGRRDALRLGGTSALGALLAACGVQGKGKPEASVAPDAVAKFWSGKVKNGKLDFANWPLYMDPKKPQLKKFTEKTGITVNYQEVIQEMGPWFAKVQPQLSAGQSIGFDLMVITNSVQFGQFRSGGFLAPLDHSKLPNYAANAGKSYANEAFDPGNVFSIPWASGITGIAYDIKKTGREITKLADLWDPQFKGKVGMFSDTQELANFGLLAAGLKPAGSGEAEWKQAAEKLKQQKSAGMVRNYYDQSYVDALGKGEVWLTQAWSGDIFQKNVSDGTDFRFVIPEEGGTIWTDNMTIPITAANPVDAIMMMDFFYEVENAASLAEFINYVCPVPAAQDQIKKDAAAASGDDKKTLTMVAGSPLVFPGQSDYDKLHYYIDFNTQEEQQNFQRIFEPITLS

Crispr_ID: NZ_LT827010_8

• CRISPR_ID: NZ_LT827010_8
• CRISPR_location: 2905720-2905949
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT827010_8

Consensus_repeat	Method
CGCCCCGAAGCCCAGACGGCGCCGTACCCCGCCGACGACCGCCCCGAACCCGAGACGGCGCCG	PILER-CR

spacers of NZ_LT827010_8

>8.1|2905783|39|NZ_LT827010|PILER-CR
CACCCCGCCGGCGACCGCCCTGGCCGCCGCCCTGGCCGC
>8.2|2905885|58|NZ_LT827010|PILER-CR
GGCCCGCCGCCCGGACGCCGAGACGGCGCCGTACCGCGCCGGCGCCCGTCCGGCCCGT

CRISPR arrays and Neighbor proteins around NZ_LT827010_8

CRISPR arrays

The CRISPR arrays of NZ_LT827010_8

>merge|NZ_LT827010|8|2905720-2905949|PILER-CR
ACCGCCCCGAACCCGAGACGGCGCCGCACCCCGCCGGCGACCGCCCTGGCCGCCGCCCTGGCCGCCGCCCGGAGGCCGAGACGGCGCCGTACCCCGCCGGCGACCGCCCGGCCCGCCGCCCGGACGCCGAGACGGCGCCGTACCGCGCCGGCGCCCGTCCGGCCCGTCGCCCCGAAGCCCGGGCGGCGCCGTACCCCGCCGACGACCGCCCCGAACCCGAGACGGCGCCG

>NZ_LT827010|8|1|2905720-2905949|PILER-CR
ACCGCCCCGAACCCGAGACGGCGCCGCACCCCGCCGGCGACCGCCCTGGCCGCCGCCCTGGCC	GCCGCCCGGAGGCCGAGACGGCGCCGTACCCCGCCGGCG
ACCGCCCGGCCCGCCGCCCGGACGCCGAGACGGCGCCGTACCGCGCCGGCGCCCGTCCGGCCC	GTCGCCCCGAAGCCCGGGCGGCGCCGTACCCCGCCGACGACCGCCCCGAACCCGAGAC
GGCGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014689970.1|2902318_2904739_+|endo-1,4-beta-xylanase	unknown	unknown	gnl|CDD|281639
NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease	unknown	unknown	gnl|CDD|224535
NZ_LT827010.1|WP_014689978.1|2890160_2891408_-|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|366161
NZ_LT827010.1|WP_014689963.1|2911919_2912558_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689975.1|2894894_2896259_+|family-43-glycosylhydrolase	unknown	unknown	gnl|CDD|350130
NZ_LT827010.1|WP_014689965.1|2907298_2910178_-|discoidin-domain-containing-protein	unknown	unknown	gnl|CDD|199882
NZ_LT827010.1|WP_014689976.1|2893248_2894895_+|alpha-galactosidase	unknown	unknown	gnl|CDD|269893
NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein	unknown	unknown	gnl|CDD|274368
NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase	unknown	unknown	gnl|CDD|224490
NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase	unknown	unknown	gnl|CDD|307151
NZ_LT827010.1|WP_014689969.1|2904954_2905686_+|AbfB-domain-containing-protein	unknown	unknown	gnl|CDD|377497
NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein	unknown	unknown	gnl|CDD|238092
NZ_LT827010.1|WP_014689977.1|2891464_2892823_-|endo-1,4-beta-xylanase	unknown	unknown	gnl|CDD|366032
NZ_LT827010.1|WP_014689971.1|2900572_2902096_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|377497
NZ_LT827010.1|WP_014689964.1|2910306_2911839_-|Otogelin	unknown	unknown	gnl|CDD|223021
NZ_LT827010.1|WP_014689967.1|2906585_2906855_-|DUF2277-domain-containing-protein	unknown	unknown	gnl|CDD|378364
NZ_LT827010.1|WP_014689966.1|2906922_2907312_+|DUF1992-domain-containing-protein	unknown	unknown	gnl|CDD|378159
NZ_LT827010.1|WP_014689973.1|2896518_2898816_+|glycoside-hydrolase-family-127-protein	unknown	unknown	gnl|CDD|369609
NZ_LT827010.1|WP_155123486.1|2892856_2893147_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689972.1|2898847_2900239_+|cellulose-binding-domain-containing-protein	unknown	unknown	gnl|CDD|281639

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014689970.1|2902318_2904739_+|endo-1,4-beta-xylanase	gnl|CDD|281639	pfam03664, Glyco_hydro_62, Glycosyl hydrolase family 62. Family of alpha -L-arabinofuranosidase (EC 3.2.1.55). This enzyme hydrolyzed aryl alpha-L-arabinofuranosides and cleaves arabinosyl side chains from arabinoxylan and arabinan.	9.71708e-157
NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	7.82995e-69
NZ_LT827010.1|WP_014689978.1|2890160_2891408_-|cellulose-binding-domain-containing-protein	gnl|CDD|366161	pfam00553, CBM_2, Cellulose binding domain. Two tryptophan residues are involved in cellulose binding. Cellulose binding domain found in bacteria.	2.1998e-27
NZ_LT827010.1|WP_014689975.1|2894894_2896259_+|family-43-glycosylhydrolase	gnl|CDD|350130	cd18618, GH43_Xsa43E-like, Glycosyl hydrolase family 43, including Butyrivibrio proteoclasticus arabinofuranosidase Xsa43E. This glycosyl hydrolase family 43 (GH43) subgroup belongs to the GH43_AXH-like subgroup which includes enzymes that have been characterized with beta-xylosidase (EC 3.2.1.37), alpha-L-arabinofuranosidase (EC 3.2.1.55), alpha-1,2-L-arabinofuranosidase 43A (arabinan-specific; EC 3.2.1.-), endo-alpha-L-arabinanase as well as arabinoxylan arabinofuranohydrolase (AXH) activities. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many GH43 enzymes display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. AXHs specifically hydrolyze the glycosidic bond between arabinofuranosyl substituents and xylopyranosyl backbone residues of arabinoxylan. This subgroup includes Cellvibrio japonicus arabinan-specific alpha-1,2-arabinofuranosidase, CjAbf43A, which confers its specificity by a surface cleft that is complementary to the helical backbone of the polysaccharide, and Butyrivibrio proteoclasticus GH43 enzyme Xsa43E, also an arabinofuranosidase, which has been shown to cleave arabinose side chains from short segments of xylan. Several of these enzymes also contain carbohydrate binding modules (CBMs) that bind cellulose or xylan. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	3.08416e-160
NZ_LT827010.1|WP_014689965.1|2907298_2910178_-|discoidin-domain-containing-protein	gnl|CDD|199882	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	1.41181e-29
NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.1207e-55
NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	4.86207e-96
NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	2.61779e-134
NZ_LT827010.1|WP_014689969.1|2904954_2905686_+|AbfB-domain-containing-protein	gnl|CDD|377497	pfam05270, AbfB, Alpha-L-arabinofuranosidase B (ABFB) domain. This family consists of several fungal alpha-L-arabinofuranosidase B proteins. L-Arabinose is a constituent of plant-cell-wall poly-saccharides. It is found in a polymeric form in L-arabinan, in which the backbone is formed by 1,5-a- linked l-arabinose residues that can be branched via 1,2-a- and 1,3-a-linked l-arabinofuranose side chains. AbfB hydrolyzes 1,5-a, 1,3-a and 1,2-a linkages in both oligosaccharides and polysaccharides, which contain terminal non-reducing l-arabinofuranoses in side chains.	1.80507e-38
NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein	gnl|CDD|238092	cd00161, RICIN, Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ligand binding occurs on exposed surfaces of the compact domain sturcture.	8.9447e-20
NZ_LT827010.1|WP_014689977.1|2891464_2892823_-|endo-1,4-beta-xylanase	gnl|CDD|366032	pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.	1.64178e-148
NZ_LT827010.1|WP_014689971.1|2900572_2902096_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|377497	pfam05270, AbfB, Alpha-L-arabinofuranosidase B (ABFB) domain. This family consists of several fungal alpha-L-arabinofuranosidase B proteins. L-Arabinose is a constituent of plant-cell-wall poly-saccharides. It is found in a polymeric form in L-arabinan, in which the backbone is formed by 1,5-a- linked l-arabinose residues that can be branched via 1,2-a- and 1,3-a-linked l-arabinofuranose side chains. AbfB hydrolyzes 1,5-a, 1,3-a and 1,2-a linkages in both oligosaccharides and polysaccharides, which contain terminal non-reducing l-arabinofuranoses in side chains.	3.97071e-53
NZ_LT827010.1|WP_014689964.1|2910306_2911839_-|Otogelin	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	4.46456e-07
NZ_LT827010.1|WP_014689967.1|2906585_2906855_-|DUF2277-domain-containing-protein	gnl|CDD|378364	pfam10041, DUF2277, Uncharacterized conserved protein (DUF2277). Members of this family of hypothetical bacterial proteins have no known function.	2.97062e-34
NZ_LT827010.1|WP_014689966.1|2906922_2907312_+|DUF1992-domain-containing-protein	gnl|CDD|378159	pfam09350, DUF1992, Domain of unknown function (DUF1992). This family of proteins are functionally uncharacterized.	1.23991e-19
NZ_LT827010.1|WP_014689973.1|2896518_2898816_+|glycoside-hydrolase-family-127-protein	gnl|CDD|369609	pfam07944, Glyco_hydro_127, Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.	7.09925e-169
NZ_LT827010.1|WP_014689976.1|2893248_2894895_+|alpha-galactosidase	gnl|CDD|269893	cd14792, GH27, glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively.	2.47083e-138
NZ_LT827010.1|WP_014689972.1|2898847_2900239_+|cellulose-binding-domain-containing-protein	gnl|CDD|281639	pfam03664, Glyco_hydro_62, Glycosyl hydrolase family 62. Family of alpha -L-arabinofuranosidase (EC 3.2.1.55). This enzyme hydrolyzed aryl alpha-L-arabinofuranosides and cleaves arabinosyl side chains from arabinoxylan and arabinan.	5.00286e-155

Protein sequences

>NZ_LT827010.1|WP_014689969.1|2904954_2905686_+|AbfB-domain-containing-protein
MPESPRSDRRPILALAAATLTVLVGYSAVATFLLRTERSPQAMPAPQPPPVWTMPSAQPPVSVAPAPSTRPVLDPVSRHSPAAPVPPPRPSRTTAGRRTAPPRLLAGTTLGLGFAGFPEYRIRRWDTAVIVAAVTAASSSHDRRDARFTVRAGRADPRCVSFESAGEPGRFLRHREFLLRLEPADGSSLFDQDATFCPERTGGGFALRSVNYPQRHLMLAADGIRLEPSATRQATVFEACPAL
>NZ_LT827010.1|WP_014689970.1|2902318_2904739_+|endo-1,4-beta-xylanase
MNARSRPRRLRTLLPVLLTATVAAGAALFFAGTSDAASTLGASATARNRYFGAAIAASKLGDATYAGILKREFTAVTPENEMKWDATEPSRGSFTFTAGDRIVTQAQANGQRVRGHTLAWHSQMPGWAQALSGSTLRSAMLNHVTQVATHYRGKIYAWDVVNEAFADDGRGTRRDSSLQRTGNDWIEAAFKAARTADPSARLCYNDYNTDGINAKSTAVYAMVKDFKARGVPIDCVGFQSHLTGAMPADYQANLQRFADLGVDVQITELDIAGSGQADAYAAVTRACLAVARCAGITVWGIRDSDSWRTGTNPLLFDAGGAKKAAYTAVLNALNAGGGSTGSTIAPATAIDTSAWYVLVNRNSGKALDVYNLATTDGARIAQFTRNDQTQQQWQFVDSGGGFYRLKSKLSGKVLDVSGKSTADGGAIVQWADNKGANQQFSVQSGNGFIQLINRNSGKAVEVQGAATTDGANVVQYTDGNGTNQQWQLVPVGGGSTPTTSPASGSCALPSSYRWTSTGALATPKSGRVALKDFTTVPYNGRHLVYATTHDTGSSWGSMSFSPFTDWTDMASATQNSMNFAAVAPTLFYFAPKSIWVLAYQWGGSAFSYRTSSDPSNPNGWSAAKTLFSGSITGSGTGPIDQTLIGDGTNMYLFFAGDNGKIYRASMPIGTFPGSFGTSSAVVMSDSTSNLFEAVQVYKVQGQSRYLMIVEAVGSGGRYFRSFTATSLGGSWTPQAATEANPFAGKANSGATWTNDISHGELVRATADQTMTVDPCHLQLLYQGRSPSSGGDYGLLPYRPGVLTLQR
>NZ_LT827010.1|WP_014689971.1|2900572_2902096_+|sigma-70-family-RNA-polymerase-sigma-factor
MAATRTDAAGLVRAAQAGNRAARDELVGAYLPVVYTIVRQALDTDPDVDDVAQDIMLRVLRQLRSLRSPDSFRSWLVAIALRQVSTHQHRRARDAARAVPIDEAAGVPDVGAEFEGVTGLRADLSAQRRQVRRAGRWLDPDDRSLLSLWLLEASGHLTRAELADALGVTVVHAGVRVQRMRAQLEVSRAIVAALDAEPRCPRLGAELAGWPGTPGPRWRKRLARHVRGCPVCTRAAGDLVPAERLLPGLLLLPVPAALTATVLAKSVGAGAVLSVAAGKAGVFGQLAALAAAHPVVTAVTAGTLIVGATAGAVSVTAPEVPRPATIARTPQPATIAAPAPVTARATTGATRGTTPRPAGTGTLRAGPVSLEAANATGRYITAAGSYGMLIGTGRGGPAATRQPATFRAVAGLNDQRCFSFRAADGRYLRHASWRLRLNADDGTALFRGDATFCPGAGQAAGSITLESSNYPGWFLRHRGDELWVDQFDGSAAFRADGSFLVRPGLAG
>NZ_LT827010.1|WP_014689972.1|2898847_2900239_+|cellulose-binding-domain-containing-protein
MKRTRPISAYAAAAGVGLLASTAAVMTVPAHAAAAGCSVTYAVSSQWDGGFGANVSVTNLGDPLTGWTVTWTYGAGQTVTQAWNATVTQSGSAVTAKNVAYNGSVATGGTVSFGFNGSWTGSNPAPAGFAVNGVACTGSPGSPSPSSPSPSSPSPSPSTPGGTCTLPSTYRWSSTGALAQPKSGWVALKDFTNVVYNGKHLVYASDVAGSGYGSMAFTPFTDWSDMAAAGQNGMSQGTVAPTLFYFAPKNIWVLAYQWGPTAFSYKTSTDPTNANGWSAPQTLFTGSITGSGTGVIDQTLIGDGQNMYLFFAGDNGRIYRASMPIANFPGSFGSSYTTVLSDSTNNLFEAVQVYRVQGQNQYLMIVEAIGSRGRYFRSFTASSLGGSWTPQAASESNPFAGAANSGATWTNDISHGDLVRNNPDQTMTVDPCHLQLLYQGKNPGAGGTYDQLPWRPGLLTLQR
>NZ_LT827010.1|WP_014689973.1|2896518_2898816_+|glycoside-hydrolase-family-127-protein
MTPFPISRRGLLQAAGAGAVAAGLGPISRADAAAVAPARADLGVSAFPFDLGQVRLTTGRFLDNQTRTLNYLRFVDADRLLYNFRANHGRSTGGAAANGGWDAPDFPFRTHVQGHFLTAWAQAWAALGDTTCRDRANYMVAELAKCQAANGYLSGFPESDFTALEAGTLSNGNVPYYCVHKTLAGLLDVWRLIGGTQARDVLLRLAGWVDTRTARLTTSQMQAMLGTEFGGMNEVLADIYQQTGDGRWLATAQRFDHAAVFTPLAAGADQLNGLHANTQVPKWVGAVREYKATGTTRYRDIGLNAWNITTGAHTYAIGGNSQAEHFRAPNAIAGYLTNDTCEHCNSYNMLKLTRELWLTDPDRAAYFDFYERALLNHLIGAQNPADSHGHITYFTPLRPGGRRGVGPAWGGGTWSTDYASFWCCQGTGVETNTKLMESIYFFSGTTLTVNLFTPSVLSWAERGITVTQATAYPVSDTTTLTVSGTPSGTWSIRVRIPGWTTGATLAVNGVAQGVGATPGGYATVTRAWAAGDVLTVRLPMRVIMQPAADNPAVQAITYGPVVLCGNYGGTTLSAHPSLNVSSIARTGSGSLAFTATANGATVSLGPFPDAQGFDYAVYWNTGSGGEAAYQVVNVASGLVLGVQDMSTADGGRVIVWGDTGTADHRWVQVPDGGAVRFRNVNSGKVLGVQNMATTDNAPVLQWADNGTADHRWTLVANADGSYRIRNVNSGRVLAVSGGASTWGSQVVQTSDTGGTGNNWRLVRVA
>NZ_LT827010.1|WP_014689975.1|2894894_2896259_+|family-43-glycosylhydrolase
MPKRSWAAALLILASLAVPSAAHADNPIVQTVYTADPAPMVYNGRVYLYTGHDEDNSTYYTMKDWRLFSSADMVNWTDHGSPMSLATFSWAGANAWAGQVVPRNGKFYWYVPVTDRATGRMAIGVGVANSPTGPFTDALGHPLAENGEIDPTVFIDDSGQAYLYWGNPNLWYVRLNPDMISYTGGIQQIPLTTAGFGTRTGSTNRPTLYEEGPWVYKRNGTYYNVFAAKCCSEFIGYSTAPGPTGPWTYRGTVMPTQGGSFTNHPGVIDFNGNSYFFYHNGALPGGGGYTRSVAVERFSYHADGSIPTITMTTGGAPQVGTLNPYVRQEAETIAWSSGVETEATSGGRNVGYLENGDYIKVKGVAFGTGATSFSARVASATSGGRLELRLGSATGAVVGTCTVPGTGGWQTWTTVTCPVSGATGTPDLYLRFTGGSGYLFNVDWWQFAGAGSAR
>NZ_LT827010.1|WP_014689976.1|2893248_2894895_+|alpha-galactosidase
MPRSSLPGRRRWFRTAILAVLCVAGVIALPGSAAQALDNGVARTPPMGWNSWNTFGCNISESLIRQMADAVVSSGMRDLGYQYVVVDDCWFNPNRDSAGNLQGDPTRFPSGMKALGDYLHAKGLKFGLYEVPLDKTCAQYFNSYPGATGSQGHEAQDARQFAAWGVDYLKYDWCSPTGTINDQVTTFAKMRDALAATGRPIVYSINPNSVHAKTGPQRNWGDVANMWRTTEDISAAWDTGQTNGYPMGVKNIVDVTVPLAGYARPGQFNDPDMMEVGRSGLTDTEQRSHFALWTMLAAPLIAGNDLRSMSTATQTILKNPRLIAIDQDSLGLQATQVSNDGTRRVLAKKLSNGDVAVALYNQGGATTTVSTTAAAIGKSGGSLTLQDAWTGGTTTSTGAISASVPAHGTVVYRVSGGGTGTPPAGATLVSASSGRCLDVPNSATANGTQPAVWDCNGGANQQWTAGGATLQSLGKCLDAPTGATAGSKVQLWDCNGGTNQQWTLNADGTIRGTASGLCLDVDHNLTANGTPVLLWTCTAAVNQRWSRG
>NZ_LT827010.1|WP_155123486.1|2892856_2893147_+|hypothetical-protein
MNGNVANTFRGKARSDHRGGAGITISDPEIDDRKSVISGAVPWSCDEIGFFGWCTKLFVSGATWADAGRPGACRERAAKDLLNVWKHPDNLRKQVC
>NZ_LT827010.1|WP_014689977.1|2891464_2892823_-|endo-1,4-beta-xylanase
MSLLRRTRSLLLASAAAGVVVAASVAVIGTAEAATTLGASAAQTGRYFGAAIAAGRLGDTTYTGILTREFNAVTPENEMKWDATEPSQGRFTFTNGDRILNQGLTNGSRVRGHALLWHNQQPGWAQALSGSALRSAAINHVTQVATHYKGKIYAWDVVNEAFADGGSGARRDSNLQRTGNDWIEAAFRAARAADPGAKLCYNDYNTDGINAKSTGVYTMVRDFKSRGVPIDCVGFQSHLGTGIPGDYQANLQRFADLGVDVQITELDVAQGGNQANVYASVTRACMAVSRCAGITVWGIRDTDSWRSGENPLLFDGSGNKKAAYTSVLNALNAGGTTTSPSAPSPSTSVSTPPQPSGACSASVSLNSWNGGFVATIRVTAGSAPITGWNVGVALPAGSAVTSTWSATAGGSTGTVSFRNASYNGQLAAGGTTEFGFQGTGTGPTATPTCAAA
>NZ_LT827010.1|WP_014689978.1|2890160_2891408_-|cellulose-binding-domain-containing-protein
MTRRTVTAILCALALATATLTGLFGTGVPATAAVAGCGKAPTLTSGTRTISSGGQNRTYILRVPDGYDRNHPYRLMFAFHWLNGTAADVATGGPAGATWAYYGQQRLAGATTILVAPQGIDNGWANPGGRDLALVDALTALIEGDLCVDTSQVFALGWSYGGAMSYAVACARPAVFRAVAVLSGANLSGCSGIGQPVAYLGIHGIHDSVLDISLGRGLRDSFVRANGCTAQNPPEPARGSLTHVVTAYTGCRTGHPVEWAAFDGDHTPEPVDGTTATDGARTWTGAEIAKFFAQLPSTTPPVSPSVTPSGTPGGQPGGCAVTYRVVNSWPGGFQAEVTVTNTGTTPTSGWRVGWTLPAGQSISQVWSGSLSVSGNAVTVVNATYNGMLDPGAAATFGLIASGSPAITPAIACTLP
>NZ_LT827010.1|WP_014689967.1|2906585_2906855_-|DUF2277-domain-containing-protein
MCRSIHQLHNFEPPATTDEVQAAALQYVRKIAGTTRPSQANQAVFDEAVAAITAATQALLDGLVTTAAPRDREVEAAKARARAERRYAS
>NZ_LT827010.1|WP_014689966.1|2906922_2907312_+|DUF1992-domain-containing-protein
MGAYWYESSIDRQLREATERGEFDNLPGAGKPLAGHGEEYDEDWWVKDWLRREGATAGVVPPTLALRRAAEDLTTVVDRLHTEREVREHVADLNTRIDKARRGHLDGPPVILPPFDADAVVRAWRIRRP
>NZ_LT827010.1|WP_014689965.1|2907298_2910178_-|discoidin-domain-containing-protein
MRVRLAATLSLCLLLGTAVALHRSGRAAPAADPHAGHILPTAVPVAVTTALPLPHTGWKVTADSGQTSAAKAIDGAAGTAWLSGTTALPHRLAIDTGNRVAVSGLTYLPRASTATGRIGRYRVQTSDNGTTWAAPVATGTFADDATLKTVTFGTVITRYVRLVAVTEAGNRGRQVAAAEVDLLGGTDPALPRTGWTATADSQETAAANGAAANALDGDTRSIWHTAYSVAPAAPLPHTFTVDMRVTNLVSGLSYLPRQDGGRNGLIGRYRIETSMDGTTWGPAAATGAFIDSQDAQTVTFAPALARFVRITALSEAGNRGPWSSAAEINLLGRPDPTLARTGWTVTADSEETAAENGRAVNVLDGDPATIWHSAWSATPVPGLPHSVTVDLHHAVPVGGLSYLPRPASPNGRIGRYRIATSSDATTWTDRVTDGVFADNPARQTVIFPPATARYVRLTAVTEAGTRGPWSSAAELDLLGPAGSVAPKRGVWSAPVGFPLVPVAAAQLPNGRILTWSAFKADTFSGGGGLTLTATYDPATGVVTQRSVSETGHDMFCPGIATLPDGRIVVTGGNNSEKTSIYDPATDAWTAGPAMTTPRGYQASATLGDGRVFTVGGSWSGGAGGVNGGRHKAGEVFSPATGWTALPGADAAPMLTADSNPNGDYRKDNHAWLFAWSGGRVLQAGPSRAMNWYTTAGTGGVSPAGVRGDDGDAMNGNAVMYDTGKILTVGGAPNYENNDATANAYVLTIAGSTVTTRKIAPMANARAFHNSVVLPDGKVAVFGGQNYPVPFSDNTAVLQAELFDPVTETFSPLSPAAMPRTYHSVALLMPDGRVFTGGGGLCGAGCATNHFDAEIFTPPYLVGVKSRPVITSAPTTAANGSKITVTTDKSIKSFALVRMGTATHSVDTDQRRLSLPQVAVSGGYQLTIPADPGVAVPGYWMMFAVDAKGVPSIARTIRVF
>NZ_LT827010.1|WP_014689964.1|2910306_2911839_-|Otogelin
MATDDFWSKFRRWRRARPFWSGLLLLLSGLELLYSSNLSLGNLQIHIGPQGFLSYLLPILMLICGALVMFSPAQRMFYGIVGLLTALYSFIGLNLGGWFIGMLLGIVGGALALSWSPAPHRPATALQGPLDFAGPSQGEPVPAEGTDTRHLEVAGHDDRPHEQPVVSDPSILPGLAPEPEGEDPRGSLPGPRRGLNRKALAIITLPILVGATMLIGSRLPASADDCPAGLPSIKTSASPSKTGGKKTPATIPARPAGKTPTKTATTTTPAPATSTSAAAASNDSNPIVDGIHSVVDGVGNLLGIGGNESPAPSASPSASASKAAEPAATGTTAPGAAPAKTTAPAPARTTSKPAADSDVIPCLGARQENVVADGSVPRSAIKPGVMKVDSLTMYNSTYKGVADVPTANGTIKALQFDMDKAVNKPFSLTIDEPGDAVTTIKSAELTTTGNVHFYTPKMTGNLFGLIPVTFTPEQPPPLTLPILWFTNVTIDLAFVSCNTLTGQPLQITES
>NZ_LT827010.1|WP_014689963.1|2911919_2912558_-|hypothetical-protein
MEDSQSAPATGRTNWRRFAVAVGVPTAVAAGLVVALQTGALAANFVISGTQFKLSADTLEGNGFTQYSDALVDGSGKPRAAAMSGISSATITNLCQSVSQKTPLGTITLQIKAATGVKASDDDSKKVQASNLLIGMSELSGDATFTNIEIGRDAGNLNRAGDAKGAVGGFGQQAEHVTINSLKQQAYSTSASTFKLTGMSLKLLTGDGNECY
>NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein
MRLQRRLNLGFAALLGLFTAFLVVQFGTGGRLRDDHDRRSARIAAAREANQHALQRMTDAETGVRGYQLTGERLFLEPYENGRGAALAALGTAAEQTRDPQVRELVEAERQAAYDWLAQYAASVIDRQSRATRTDPALGKHLFDRVRALNAAADDAIAAEQHAENAAGRRRSRILGAGSAALVLAVLAAGYLLVRVSRRQLLVPLARLGDTIRRQAAGDRSARAELLGAAELRTVIEALNDLSAQTEELLAAEQARTARAWLCQAVVAELQQEGADPAQVGHRVVARIGGALGADAVHGNLFVPGTGQIAVRWPPEAPDPAPDAVTGIRDMPAGQPAIRAGGLAVTIGGDPDCPGGWVLVVREFLPQFTAPEHRLLASVAGEIERALRQLGIRVHQELLIGQLRMLDQRKDVFIQTVTHELRTPLTSILGYAEMLADEDEELNPMQRRSLNAILRNGHRLQDTINDLLLLDRPATAVDAVTEPLDLAVLATTVHAELQAAAQAKNLAVTLDAAPAWVRGDRTQLQRALRKLLENAIKFTAAGGSVTWGCDADSRHVTVTVTDTGIGIPPEDVSGLFTPFHRAGNAMDQAVQGPGLGLAIVRDIVRDHGGAIAVQSVVGRGTTFTVTLPAVPAPVALPVS
>NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease
MAAMADQIIAGGFRIVVDPVSDSVRLSAIFAVLPLLTLFLLLGVFRVRAWLAGVISLVVALVVAIAGYAMPVGQALLSASEGAAFGFFPILWIVINAIWVYNLTVVSGHFDVLRRSMERVSPDMRIQAIIVAFCFGALLEALAGFGTPVAVTVVMLTALGFAPIRAASVALIANTAPVAFGALATPIVTLATVTSGAGNDPRLTTDTLGAMVGRQTPVLALVVPLILVFVVDGRRGVRQAWPAAAVAGLVFAVAQFVASNHLSVPLTDIVASLAAAAAVVLLLRLWQPARAVGSSPLTGAAARRDASAGDGALTGTVARRDASAGDGALTGTVARRDASAGDGALTGTVARRDASAGEGPPTGTAQRRDVAVEGSLLSGTGLRRDAPAEVARAYAPYLIIIVIFAIANLGPVKSALARSPWTVIFAWPGLHVLSATGKPLSSTNFTLGWLPAAGTLLIIAGILSAVVLRVRPGAAARAYGRTYAELRQPIVTVMAVLALAYVLNQSGQTNTLGAFLATAGGVFVFLSPILGWIGVAVTGSDTSANALFGALQVQTAAKAGLDPLLLAAANSSGGVLGKMVSPQNLAIAAGAVGMAGREGDIFRKVILWSAVLLLGMCVLVTLQSTPILGWMIPG
>NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase
MADLILMADRIHTLTPGIRPTAVAVAGGRITALGDRADVRDWRGPGTRIIDVGTATITPGLVDGHTHPVHGIGLTRGLDLSGVHTLAGLKDALRSASSVCAAPDGWLEGWGLDPDAFKGAPLTAAPLIEVLGPHVPVFLRFFDAHSALVSPRALDIAGPAARSHAGVVRDADGQPTGCLLELEAVETVRAVLPPDPPGTRLRRLRELLTRMAASGLTAANAMDFEEDSLALFRALEDAGDLPMRWRCAPLVTPGADLADIVAKQRLHGRRWQVEGAKFMIDGTVDGGTAWLDEPDSLGESTASIWPDPGEYAAAARHLAGHGVPTVSHAIGDAGIRYALDTVGRLPRQRVPHRIEHLETMPGDLIGRFAALDVTASMQPTHCTHHTRADHTDNWSRRLGKLRADRAFRARDLRDSGARLVLGSDWPIAPFDPRGILAAARLRRPAGAVDTSPVLPAQGLTARMALEGYTSQAAEAAGIGDSGRIAAGCRADFSVFELDPLGVDADEFAESAVVMTVVEGDVLFGGSFAADG
>NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein
MSSAASAGAQAPAAVVVGSGTAGTGILVSGNGLCLDLPGAVPVDDSVIQVFDCNRSAAQVWTLGTDGTLQVMGKCALLVGDSTVHLTSCDLRTTAQWRITGDHQLINAASNRCLTDPSQGARPGTRVVVVTCTGASDQRWSLS
>NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase
MTVMTDAVDTSAVAKKKTPANTPEGVDAELVGRLVEQARAAGLQLTGEGGLLQQLTKRVIEAALDGEITDHLGYEKHDPAGKDGGNSRNGTRAKTVLTDVGPVEITVPRDRDGSFEPQIVKKRQRRLTGVEDMVLSLSAKGLTTGEISAHLAEVYGADVSRQTISTITDKVMDGMAEWQNRPLDRVYPVVFLDAINVKIRDGKVANRPIYVALAVTVEGTRDILGLWAGDGGEGAKFWFSVCTELKNRGVEDVLMAVCDGLTGLPDAINTVWPRTVVQTCVVHLLRNSFKYAGRQHYDAIAKALRPVYTAPTEAAAEHRFLEFAEAWGGRYPAIVRLWENAWAEFVPFLAFDAEIRKVVCSTNAIESVNARIRRAVRARGHFPNEQAALKCVYLAVMSLDPTGTGRRRWAIRWKPALNAFDFAFEGRLTAGRN

Crispr_ID: NZ_LT827010_9

• CRISPR_ID: NZ_LT827010_9
• CRISPR_location: 2931835-2931919
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_9

Consensus_repeat	Method
CCGGTGTCTGAGCCCGGTGTCTG	CRISPRCasFinder

spacers of NZ_LT827010_9

>9.1|2931858|39|NZ_LT827010|CRISPRCasFinder
AGCCCGAGGACCCGCAGGGGTGTGTGGCCGCGGATCGTG

CRISPR arrays and Neighbor proteins around NZ_LT827010_9

CRISPR arrays

The CRISPR arrays of NZ_LT827010_9

>merge|NZ_LT827010|9|2931835-2931919|CRISPRCasFinder
CCGGTGTCTGAGCCCGGTGTCTGAGCCCGAGGACCCGCAGGGGTGTGTGGCCGCGGATCGTGGCGGTGTTTGAGCCCGGTGTCTG

>NZ_LT827010|9|7|2931835-2931919|CRISPRCasFinder
CCGGTGTCTGAGCCCGGTGTCTG	AGCCCGAGGACCCGCAGGGGTGTGTGGCCGCGGATCGTG
GCGGTGTTTGAGCCCGGTGTCTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014689944.1|2939883_2940930_+|winged-helix-DNA-binding-domain-containing-protein	unknown	unknown	gnl|CDD|377630
NZ_LT827010.1|WP_014689946.1|2936111_2938052_-|glycosyltransferase-family-39-protein	unknown	unknown	gnl|CDD|224720
NZ_LT827010.1|WP_014689943.1|2941030_2942341_+|glycoside-hydrolase-family-18	unknown	unknown	gnl|CDD|119350
NZ_LT827010.1|WP_014689941.1|2943376_2945299_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_014689942.1|2942490_2943048_-|dihydrofolate-reductase-family-protein	unknown	unknown	gnl|CDD|334719
NZ_LT827010.1|WP_014689950.1|2932237_2933386_-|membrane-dipeptidase	unknown	unknown	gnl|CDD|366534
NZ_LT827010.1|WP_014689945.1|2938191_2939820_+|glucose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|234679
NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein	unknown	unknown	gnl|CDD|274368
NZ_LT827010.1|WP_014689953.1|2928973_2929240_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein	unknown	unknown	gnl|CDD|238092
NZ_LT827010.1|WP_014689948.1|2934886_2935831_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase	unknown	unknown	gnl|CDD|307151
NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease	unknown	unknown	gnl|CDD|224535
NZ_LT827010.1|WP_014689956.1|2924985_2925645_-|MerR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223860
NZ_LT827010.1|WP_099343760.1|2925665_2926400_+|cyclase-family-protein	unknown	unknown	gnl|CDD|377240
NZ_LT827010.1|WP_014689954.1|2926369_2928670_-|immune-inhibitor-A	unknown	unknown	gnl|CDD|368494
NZ_LT827010.1|WP_172898883.1|2922325_2924968_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|274782
NZ_LT827010.1|WP_155123489.1|2935834_2936056_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase	unknown	unknown	gnl|CDD|224490
NZ_LT827010.1|WP_155123488.1|2933516_2934611_+|endoglucanase	unknown	unknown	gnl|CDD|226609

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014689944.1|2939883_2940930_+|winged-helix-DNA-binding-domain-containing-protein	gnl|CDD|377630	pfam06224, HTH_42, Winged helix DNA-binding domain. This family contains two copies of a winged helix domain.	1.65517e-58
NZ_LT827010.1|WP_014689946.1|2936111_2938052_-|glycosyltransferase-family-39-protein	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	1.1644e-25
NZ_LT827010.1|WP_014689943.1|2941030_2942341_+|glycoside-hydrolase-family-18	gnl|CDD|119350	cd02871, GH18_chitinase_D-like, GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus.	7.45241e-102
NZ_LT827010.1|WP_014689941.1|2943376_2945299_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.82923e-64
NZ_LT827010.1|WP_014689942.1|2942490_2943048_-|dihydrofolate-reductase-family-protein	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	2.37845e-20
NZ_LT827010.1|WP_014689950.1|2932237_2933386_-|membrane-dipeptidase	gnl|CDD|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	5.71871e-120
NZ_LT827010.1|WP_014689945.1|2938191_2939820_+|glucose-6-phosphate-isomerase	gnl|CDD|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.1207e-55
NZ_LT827010.1|WP_099343760.1|2925665_2926400_+|cyclase-family-protein	gnl|CDD|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	5.66533e-42
NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein	gnl|CDD|238092	cd00161, RICIN, Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ligand binding occurs on exposed surfaces of the compact domain sturcture.	8.9447e-20
NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase	gnl|CDD|307151	pfam00872, Transposase_mut, Transposase, Mutator family.	2.61779e-134
NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease	gnl|CDD|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	7.82995e-69
NZ_LT827010.1|WP_014689956.1|2924985_2925645_-|MerR-family-transcriptional-regulator	gnl|CDD|223860	COG0789, SoxR, Predicted transcriptional regulators [Transcription].	8.08659e-07
NZ_LT827010.1|WP_014689954.1|2926369_2928670_-|immune-inhibitor-A	gnl|CDD|368494	pfam05547, Peptidase_M6, Immune inhibitor A peptidase M6. The insect pathogenic Gram-positive Bacillus thuringiensis secretes immune inhibitor A, a metallopeptidase, which specifically cleaves host antibacterial proteins. A homolog of immune inhibitor A, PrtV, has been identified in the Gram-negative human pathogen Vibrio cholerae.	3.20202e-16
NZ_LT827010.1|WP_172898883.1|2922325_2924968_-|VWA-domain-containing-protein	gnl|CDD|274782	TIGR03788, marine_srt_targ, marine proteobacterial sortase target protein. Members of this protein family are restricted to the Proteobacteria. Each contains a C-terminal sortase-recognition motif, transmembrane domain, and basic residues cluster at the the C-terminus, and is encoded adjacent to a sortase gene. This protein is frequently the only sortase target in its genome, which is as unusual its occurrence in Gram-negative rather than Gram-positive genomes. Many bacteria with this system are marine. In addition to the LPXTG signal, members carry a vault protein inter-alpha-trypsin inhibitor domain (pfam08487) and a von Willebrand factor type A domain (pfam00092).	1.81177e-114
NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase	gnl|CDD|224490	COG1574, COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only].	4.86207e-96
NZ_LT827010.1|WP_155123488.1|2933516_2934611_+|endoglucanase	gnl|CDD|226609	COG4124, ManB, Beta-mannanase [Carbohydrate transport and metabolism].	4.25213e-05

Protein sequences

>NZ_LT827010.1|WP_014689953.1|2928973_2929240_-|hypothetical-protein
MPIGPQPPGRRGTVEEPYSPLNLRLVLAAFGMVVCAALSAILFRAGWTLPGWLLAAWAAVAAVDILVIQKRRRARNRAEQGRKHSLFE
>NZ_LT827010.1|WP_014689954.1|2926369_2928670_-|immune-inhibitor-A
MAPLLTSPAEAQPQRPLTPAVHGHAGVLPEIDGRGLTRTHLRLGGKFLPQARYRPQPTARRAPAATPAVGTVRSWVGLDDTDGDLYRKDYTLRAVGRHIEVWVAKDIAFPAGDCRKNSTEVTDAQVADLVTQFDTNIYPKETATFSTPPDRSGAHPGMAGDFSGDGDKTVTLVDNVRDDNYFHFPERPTYIAGFFSAQLNELFDRNVMTIDAYDWQHRLGADPKNEPTDDLCTSRPARPRMYEGTFAHEWQHLLEYYQDPAEVDWLNEGLSDYAQTLVGYVDPRIGVHHPGFDSHIACYQGFGNVKTTYNANPRECGGPQNSLNLWDEGEPNEVLADYGITYELMVYLRDRFGVKMIAELHRDAKHQSLDALQTALPKGLKVADVLHDFQVMTLVDKEVGEPGGTVTGVPRDRVTAAELQSTVNLANPATYDKSGAAPNGADFIRLPQGLIKSVAFSGAPTLPPTPLAWKIDAGLLFSGNTSDLDETAARQVEVPTADPVLRFKTTYGMEKDFDYGYVTVSADGGKTYQAIEGNNTVKGPLGPAITGQAADVKENYDLKAYAGKKILLGFRYVTDAAVNLGGWHLGEVTLGASKITSDSLDGWKSPTQWHPIPVRGWHVSLVGLGHLRAAVVPITEVAALRGFPKVVAIVAQDDPTGTVTQYAPYTLTVDGVVQPGGGQTATPPPAASTTTKGHSTAGNTPGHATPGAAPSHSTPSHPTPGHPTPSPTRSRSTAGVTQGHATPGASPAHPTAGSGHGQPAAGGTTP
>NZ_LT827010.1|WP_099343760.1|2925665_2926400_+|cyclase-family-protein
MVTVSMIRGRMSGMLDRLRLVSLSHVNDPARISVFPGDPPFELDTVATLGGEGFYLRAVRGGEHTGTHWGAPGHFTEGGLLADELEPADLFRPAVKVDVRSACAADPAYAVTIGDLQDWEGRHGRIPDESFVIIWTGWEERFGCADFERHPGFAPETVRWLVETGRLGERGGTGTDAFSPDVSSDAGFTVSRLVYQRRRVSLEVLAHLADLPATGAWVLCGGQINRAGSGSTALIYGVVPPAAG
>NZ_LT827010.1|WP_014689956.1|2924985_2925645_-|MerR-family-transcriptional-regulator
MWTMEELVDRVRTALAAEYSGAPNGRVRDLPDRRSIRWYSTIGLVDRPLGTRGRTALYGPRHLMQLVAIKRLQAAGRTLAEIQADLSGASDESLTDLARVPSELLEADPSPPPATPRPPFWKSPPAPQTAPTHALDWAFPQSEAPSGLAEVPSPAGDPGTAPPIGADALLTGVPLGSGLILLVPGSFHLDRIDRTQLATAARPLLDLLASRGLTDRRDS
>NZ_LT827010.1|WP_172898883.1|2922325_2924968_-|VWA-domain-containing-protein
MGPGELERVRPAPGSGFGSLRTDRGNLPLDRLDVQAAISGLVARTEVTAEFVNTHDTALEATYVFPLPDRAAVVGMTMTADGRTVTAELQERAAAREQYDQAVAAGQRASIAEEERPDVFTMRAGNILAGERIVVRLSLVGPMPFEDGAATYRFPLVVAPRYIPGAPLPGPYAGDGQTADTDAVPDASRISPPVLLPGFPNPLRLSLGVTVDAAGLELGEVRSSLHAISEEGGTLRIAPGERADRDFVLRLAYAPGGNTAVAVPDNDGEEGTYQIVILPPAGDVPPRPKDVVLLLDRSGSMGGWKMVAARRAAARVIDTLTGADRFAVLTFDHQVERPDGVEPGLSEATDRNRFRAIEHLARADARGGTELLTPLTTGLGLLADSTGRDRVLVLVTDGQVGNEDQIVHEVTPLIGSTRLHTIGIDRAVNAGFLGRLAALGAGRAELVESEDRLDEAMEHIHRRIGAPVVTGLSLTADDVTALEGTRSPQRLPGLYPGVPLVVTGRYSGSTAGTFTVTGTTRDEQAFQATIPLRERAEPAVTKQWARARLRDLEDAFAAGDHTLEQQIVETSLRFGVLCRFTAYVAVDERVVNEGGEVRRVTQPVEMPSGWESTAPPMAAGMILASASSPFPGGPAPAAPGMFPPAPPIPGGPVPSRPRFAPASAKLRASHRQPDAFDDARLAGQPPIVGGPPPSADSPASPAASPPAPTSDASTPAGGSSAPTGSVPASASGPTSPAGGPQSPAGGPPSPAGGVPRSASGLPAGGGRVSPRGFGRSRQPADAGIPLADIRQLATVEAGRLRDAADHPDYERRDLLDDLASRLTVLLTPLSGDDFGPLQALITLLNGNAPLAEKWSTALRVLTEFGAPTSPKRATKPFWKR
>NZ_LT827010.1|WP_014689958.1|2920871_2922173_-|IS256-family-transposase
MTVMTDAVDTSAVAKKKTPANTPEGVDAELVGRLVEQARAAGLQLTGEGGLLQQLTKRVIEAALDGEITDHLGYEKHDPAGKDGGNSRNGTRAKTVLTDVGPVEITVPRDRDGSFEPQIVKKRQRRLTGVEDMVLSLSAKGLTTGEISAHLAEVYGADVSRQTISTITDKVMDGMAEWQNRPLDRVYPVVFLDAINVKIRDGKVANRPIYVALAVTVEGTRDILGLWAGDGGEGAKFWFSVCTELKNRGVEDVLMAVCDGLTGLPDAINTVWPRTVVQTCVVHLLRNSFKYAGRQHYDAIAKALRPVYTAPTEAAAEHRFLEFAEAWGGRYPAIVRLWENAWAEFVPFLAFDAEIRKVVCSTNAIESVNARIRRAVRARGHFPNEQAALKCVYLAVMSLDPTGTGRRRWAIRWKPALNAFDFAFEGRLTAGRN
>NZ_LT827010.1|WP_043511432.1|2919108_2919540_-|RICIN-domain-containing-protein
MSSAASAGAQAPAAVVVGSGTAGTGILVSGNGLCLDLPGAVPVDDSVIQVFDCNRSAAQVWTLGTDGTLQVMGKCALLVGDSTVHLTSCDLRTTAQWRITGDHQLINAASNRCLTDPSQGARPGTRVVVVTCTGASDQRWSLS
>NZ_LT827010.1|WP_014689960.1|2917119_2918715_+|amidohydrolase
MADLILMADRIHTLTPGIRPTAVAVAGGRITALGDRADVRDWRGPGTRIIDVGTATITPGLVDGHTHPVHGIGLTRGLDLSGVHTLAGLKDALRSASSVCAAPDGWLEGWGLDPDAFKGAPLTAAPLIEVLGPHVPVFLRFFDAHSALVSPRALDIAGPAARSHAGVVRDADGQPTGCLLELEAVETVRAVLPPDPPGTRLRRLRELLTRMAASGLTAANAMDFEEDSLALFRALEDAGDLPMRWRCAPLVTPGADLADIVAKQRLHGRRWQVEGAKFMIDGTVDGGTAWLDEPDSLGESTASIWPDPGEYAAAARHLAGHGVPTVSHAIGDAGIRYALDTVGRLPRQRVPHRIEHLETMPGDLIGRFAALDVTASMQPTHCTHHTRADHTDNWSRRLGKLRADRAFRARDLRDSGARLVLGSDWPIAPFDPRGILAAARLRRPAGAVDTSPVLPAQGLTARMALEGYTSQAAEAAGIGDSGRIAAGCRADFSVFELDPLGVDADEFAESAVVMTVVEGDVLFGGSFAADG
>NZ_LT827010.1|WP_099343758.1|2915126_2917031_+|L-lactate-permease
MAAMADQIIAGGFRIVVDPVSDSVRLSAIFAVLPLLTLFLLLGVFRVRAWLAGVISLVVALVVAIAGYAMPVGQALLSASEGAAFGFFPILWIVINAIWVYNLTVVSGHFDVLRRSMERVSPDMRIQAIIVAFCFGALLEALAGFGTPVAVTVVMLTALGFAPIRAASVALIANTAPVAFGALATPIVTLATVTSGAGNDPRLTTDTLGAMVGRQTPVLALVVPLILVFVVDGRRGVRQAWPAAAVAGLVFAVAQFVASNHLSVPLTDIVASLAAAAAVVLLLRLWQPARAVGSSPLTGAAARRDASAGDGALTGTVARRDASAGDGALTGTVARRDASAGDGALTGTVARRDASAGEGPPTGTAQRRDVAVEGSLLSGTGLRRDAPAEVARAYAPYLIIIVIFAIANLGPVKSALARSPWTVIFAWPGLHVLSATGKPLSSTNFTLGWLPAAGTLLIIAGILSAVVLRVRPGAAARAYGRTYAELRQPIVTVMAVLALAYVLNQSGQTNTLGAFLATAGGVFVFLSPILGWIGVAVTGSDTSANALFGALQVQTAAKAGLDPLLLAAANSSGGVLGKMVSPQNLAIAAGAVGMAGREGDIFRKVILWSAVLLLGMCVLVTLQSTPILGWMIPG
>NZ_LT827010.1|WP_014689962.1|2912985_2914905_+|CHASE3-domain-containing-protein
MRLQRRLNLGFAALLGLFTAFLVVQFGTGGRLRDDHDRRSARIAAAREANQHALQRMTDAETGVRGYQLTGERLFLEPYENGRGAALAALGTAAEQTRDPQVRELVEAERQAAYDWLAQYAASVIDRQSRATRTDPALGKHLFDRVRALNAAADDAIAAEQHAENAAGRRRSRILGAGSAALVLAVLAAGYLLVRVSRRQLLVPLARLGDTIRRQAAGDRSARAELLGAAELRTVIEALNDLSAQTEELLAAEQARTARAWLCQAVVAELQQEGADPAQVGHRVVARIGGALGADAVHGNLFVPGTGQIAVRWPPEAPDPAPDAVTGIRDMPAGQPAIRAGGLAVTIGGDPDCPGGWVLVVREFLPQFTAPEHRLLASVAGEIERALRQLGIRVHQELLIGQLRMLDQRKDVFIQTVTHELRTPLTSILGYAEMLADEDEELNPMQRRSLNAILRNGHRLQDTINDLLLLDRPATAVDAVTEPLDLAVLATTVHAELQAAAQAKNLAVTLDAAPAWVRGDRTQLQRALRKLLENAIKFTAAGGSVTWGCDADSRHVTVTVTDTGIGIPPEDVSGLFTPFHRAGNAMDQAVQGPGLGLAIVRDIVRDHGGAIAVQSVVGRGTTFTVTLPAVPAPVALPVS
>NZ_LT827010.1|WP_014689950.1|2932237_2933386_-|membrane-dipeptidase
MWIFDGHNDLAMRLRGWHGSSTAGLDGSRPELHTDLPRLRAGRVGAQFWSVYVPSSLPEPEAVTHTLEQIDVVYRLLAEYPDTLEAARTADDVERIVAAGRIASLIGVEGGHCLARSPGVLRSLARLGVRYVTLTHNHHTAWADSAAAPPVSGGLTAEGRALVREMQRIGVLVDLSHVAPVTMHAALDEATAPVIFSHSGARTVTDHPRNVADDVLERLPANGGVVQIPFVACFVSPAVLDWQRAADEEWQRLGLPPVQDTWPRAPRAGESDPPTATIADMTSEPAFLPWLAAHPRPDATAAEVADHVDHARAVAGIDHIGLGGDFDGTPDVPIDLPDVAAYPVLLTELESRDWSRTDLRKLAHHNVLRVLREAEQHATADL
>NZ_LT827010.1|WP_155123488.1|2933516_2934611_+|endoglucanase
MPGGQHRWTDSGGKPILMRSTLRKTVLTLTALVAGLGAATATPAQAATHAADAGCVTGAKLVPTCGVLWGGAAGGFTSAPRDKALKDWENASGRTATIFHQYHKGNEPFPTKAEIAMTADSAHPRVLLENWKIAYGTTWAAVARGGQDKRIDAFAARAKAYGKKFFLVLNHEPENDVIPRSGSGMQAKDFAAMYRHTIERLRAQGVTNVINVVAYMGNEKWMAQSWWTDLYPGDDVVDWVGLDSYVSVEKGYYHYGDFSALLDRKAKGGTLGWYDWATTRHADKPVMVAEWGAYHRVGRATDKSFVYNSVIDQLQKRPAIKAIVHFDTKHDDEGDRDISINSSAASLKAFRKLAANPIFDVKLG
>NZ_LT827010.1|WP_014689948.1|2934886_2935831_-|hypothetical-protein
MLAEISAAAYRLRLPLVLYSAVLTVATVAAGRLSPAPIGPTVATLALVAVAGVTAVLALAVMAAAQRTGSQRPALIVDGAFHTPRPGTFPLLAVAMLGLAGAAVVAPAEAGQARPVFWGAGAFGVLTLACCARAIRHGIGLTLTPHGLHADKHTGSVTIPWEAVDPRRVWSGPFEVRLRYTRPDLVRTTGWVVNPHRFRVDGIATGFVAATIQHYAANRTELVLIGQPAGQLHPATEPVSPPRSVEPWNLSSVLPLLALAAMTGAGAVAADVWAGRRWGDVSVPGLVAHLLAIQALLAAALLARGSIRLLRRRG
>NZ_LT827010.1|WP_155123489.1|2935834_2936056_-|hypothetical-protein
MIMRLDTAVDRHRRPIVLFALVWTMLAVAARRLGHADDATARESVHVLAAVAAIAIGAVLIDAIRGFRARARI
>NZ_LT827010.1|WP_014689946.1|2936111_2938052_-|glycosyltransferase-family-39-protein
MTTTAGHRARNVPERASLVALLTATAVLYLWNLSASGWGNSFYAAAAQAGAKSWKAWLFGSLDAGNAITVDKPPAAMWVMGLSARIFGVNSWAILAPQALMGVASVFLLYLAVKRWFGHGAGLLAGAALALTPVAVLMFRYDNPDALLVLLMTAAAYTTVRATEVASGKSLAWTGVLLGFGFLTKMMQAFLVLPAMALVYLVAAPAPLGRRFRHLSLAGLALVASAGWFVALVSLWPASSRPYIAGSTNNTLWELALGYNGLGRILGGAGNGGGGGGGGGNVGFGGATGIGRLFGTSMGTEISWLLPAALIALVTVLAATWTAPRTDRARAAMLLWGGWLLVTGVTFSYMSGTIHPYYTIALAPSIAAVTGIGARVLWLYRTRLWGRIVLAAMVLATAAWGFVLLGRTDWLPALRWAAVVAGVVAAAGLIVPAVALRRLAVIGIVAGLLSAGLGSAAYATATVGVAHTGSIPSSGPSGSSGMGGGPGGGGFGRTGDGAPPAGNAPAQPSPSASSSTASASPSAPFPGGGGMGRGGGADTELTALLKASTTTWSAAVSGATSAADLELASGTSVIALGGWNGSDPSPTLAEFQTYVKSGRIHYYIAGGVGGGGGMGGGSTDSSQIASWVTANYPATTVGGSTVYDLS
>NZ_LT827010.1|WP_014689945.1|2938191_2939820_+|glucose-6-phosphate-isomerase
MSEHVSDSAEWQALQGYAEKFSAVHLRDLFASDPQRGERYAAEVAGLYVDYSKNLVTDEVLSALFALAGRAKLNERIAAMFAGEHINVTEDRAVLHTALRLPRDATLVVDGQDVVADVHEVLDRMGAFADKVRSGEWVGHTGQRIRTVVNIGIGGSDLGPVMAYEALKDFSQRDIECRFVSNIDPTDLYEKTRDLDPASTLFIIVSKTFTTQETLTNAREARSWLLASLSDEAAVAKHFVAVSTNAEKVADFGIDTDNMFGFWDWVGGRYSLPSAVGLSVMISIGKERFAEMLAGYHAVDEHFRTTPVERNVPALLGLINVWYDTFLGAQSHAVLPYAQYLHRFAAYLQQLTMESNGKSVRLSGDPVSFQTGEIFWGEPGTNGQHAFYQLIHQGTKLIPADFIGFSEPNHDIGEMHDLFMSNFLAQTGALAFGRTLEQVQAEGTKPEVAPHRVMQGNHPTTTILAESLTPGTFGQLVALYEHITFTQGVIWEINSFDQWGVELGKVMANQLAPKLTAAESPADDADSSTNTLIKRYRAARGR
>NZ_LT827010.1|WP_014689944.1|2939883_2940930_+|winged-helix-DNA-binding-domain-containing-protein
MTSLLLGSVTRSSVLDITEWFGALQAQDLNSVLWSLGARLRGSTLPEIVAATENRDVVRTWPMRGTVHLVPSADAHWMLELTGVRALAGAAKRREILGLAEADADRAAEILGAALAGGGRLTRSACVATINAGGVPVSGQLGYHLLWYASQRGVTAIAPNEGSEQTFVLLDEWAPTRNAPSREEALGILAHRYFRSHGPTTAKDFAGWTMLPMKDARAGIATAGLRRVEVDGVEMWADPAVLDAGPVRGWRALPGFDEYMLGYKDRAMMATPEMLRSIIPGGNGIFQSTLVRDGRVMAVWKRTLGRKAVSITVSPLVEFTAGDWMQAEEALQPYGAFVGLPVTVKKLA
>NZ_LT827010.1|WP_014689943.1|2941030_2942341_+|glycoside-hydrolase-family-18
MRVRRQVLALIAGVGVALGTTVIYSTTGEAAVACSATVWAEGVTYTAGQQVTYQSKLYQALVTHTAYAGTGWNPAATPTLWKELGGCSGGSTPTPTPSVTTTSPSPTTSPTPTPTATGGTGCATKGRPAGKVLQGYWENWDGASNGVHPGLGWIPVNDTRITQHGYNVLMAAFPVIRSDGTVLWENGMDAGVKVPTPAEICAAKAQGATVLMSIGGAAAGIDLSSSAVADRFVATIVPILKANNFDGIDIDIETGLSGSGSISTLSTSQANLIRIIDGVLAQMPANFGLTMAPETAYVTGGSVTYGSIWGSYLPIIKKYLDNGRLWWLNMQYYNGSMYGCSGDSYSAGTVQGFTVQTQCLNNGITIQGVTVKVPYDKQVPGLPAQSGAGGGYMTPALVSQAYNSVPSIKGLMTWSINWDGSKGWTFGDNVKALQGR
>NZ_LT827010.1|WP_014689942.1|2942490_2943048_-|dihydrofolate-reductase-family-protein
MARLICTGITSLDGYIADERGNFDWSRPDEEVHSFVNDLERPIGTYLYGRRLYEVMRFWEDAEARPDSTPATVDYARVWRAADKVVYSTTLAEVTTARTRLERVFDPEVVRKAKEAADRDLSIGGPHLAAHAFRAGLVDEVQLFVSPIAVGGGTRFLPDGVRLDLKLAEQRRFANGVVYLRYRAS
>NZ_LT827010.1|WP_014689941.1|2943376_2945299_+|serine/threonine-protein-kinase
MADQEALGREYLLHEEIGRGALAVVRRATRRSGGPPLAAKLLHPELASDRRIRESFLREEAALRHLDHPGIVGFHDLVVEGGTLALLMDLVDGPDLRRHLAHRGGRLGAAETAVIVGQAAEAVAAAHRRGVVHLDLKPENLLVVRDTGPAVVRVTDFGLAVLLMDAARGVAGGTPGYTAPEIWQGATPTAAADVYSLGILLVELITGHVGGDPDALPERLAGPARSCLAPDPRDRPAAEQVGGYLRALVASGVLGPPPPVVAEGEAGDVPDPVSRRTTVRGAGSVGSPGAGGGAGAAVDPEHSGIWVGQLAGGVPLGGFLAGAPPQGGFLAGTPAQGGFLAGAPPQGRFLAGTPAQGGLLAGAPPQGGFLAGTPAQGGLLAGAPPRGGGGPRVPAAGLGGTGLVAEAPPRRREGRGMLVAAGVLAVVAAGMVGLGIAKVVGDRSHPAAAVPVSSAPAVTPSAGAGGVLPPTEQVRASASAAPVRVTLAGYAADDGGTLALSIRDGTAIAYICDGNTREAWLQGTAVDGRLALSGTGGARITGTFDALGATGKVTVAGGTHAFTLRPVQKPSGLYRTSAKVRGARIQGSWIVLPDGRQVGVLTDGGRTGPAPRFDVAGGTATVDGVAVAVTAVDVDSGAGF

Crispr_ID: NZ_LT827010_10

• CRISPR_ID: NZ_LT827010_10
• CRISPR_location: 3451437-3451589
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT827010_10

Consensus_repeat	Method
GCTGCCGCGGAGGCCGAGCGGCAGCGG	CRISPRCasFinder

spacers of NZ_LT827010_10

>10.1|3451464|36|NZ_LT827010|CRISPRCasFinder
GGTGTCGCTGATGCGGAGAAGGCGAAGGCGAACCGC
>10.2|3451527|36|NZ_LT827010|CRISPRCasFinder
AAGATCGCTGCCGACGAGCAGCGCAAGGCGCACGAG

CRISPR arrays and Neighbor proteins around NZ_LT827010_10

CRISPR arrays

The CRISPR arrays of NZ_LT827010_10

>merge|NZ_LT827010|10|3451437-3451589|CRISPRCasFinder
GCCGCCGCGGAGGCGCGGCGCCAGCGGGGTGTCGCTGATGCGGAGAAGGCGAAGGCGAACCGCGCTGCCGCGGAGGCCGAGCGGCAGCGGAAGATCGCTGCCGACGAGCAGCGCAAGGCGCACGAGGCTGCTGCGGAGGCCGAGCGGCAGCGG

>NZ_LT827010|10|8|3451437-3451589|CRISPRCasFinder
GCCGCCGCGGAGGCGCGGCGCCAGCGG	GGTGTCGCTGATGCGGAGAAGGCGAAGGCGAACCGC
GCTGCCGCGGAGGCCGAGCGGCAGCGG	AAGATCGCTGCCGACGAGCAGCGCAAGGCGCACGAG
GCTGCTGCGGAGGCCGAGCGGCAGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_043514200.1|3460252_3462124_+|acetyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl|CDD|227111
NZ_LT827010.1|WP_014690111.1|3441037_3443986_+|NACHT-domain-containing-protein	unknown	unknown	gnl|CDD|366375
NZ_LT827010.1|WP_014690109.1|3435301_3438298_-|FAD-binding-protein	unknown	unknown	gnl|CDD|223354
NZ_LT827010.1|WP_014690107.1|3433721_3434747_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043514192.1|3434900_3435293_-|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|235142
NZ_LT827010.1|WP_014690121.1|3456084_3456717_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_LT827010.1|WP_014690120.1|3455207_3455945_+|DUF2071-domain-containing-protein	unknown	unknown	gnl|CDD|378271
NZ_LT827010.1|WP_014690129.1|3467279_3468485_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035
NZ_LT827010.1|WP_014690106.1|3431195_3433442_+|catalase	unknown	unknown	gnl|CDD|236886
NZ_LT827010.1|WP_014690115.1|3447895_3450088_+|catalase/peroxidase-HPI	unknown	unknown	gnl|CDD|237891
NZ_LT827010.1|WP_014690118.1|3453970_3454942_+|phosphotransferase	unknown	unknown	gnl|CDD|270703
NZ_LT827010.1|WP_052311908.1|3458717_3460253_+|acetyl-CoA-carboxylase	unknown	unknown	gnl|CDD|178415
NZ_LT827010.1|WP_172898757.1|3446301_3447315_-|ketopantoate-reductase-family-protein	unknown	unknown	gnl|CDD|224805
NZ_LT827010.1|WP_043514195.1|3445327_3446296_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690112.1|3443982_3445359_+|hypothetical-protein	unknown	unknown	gnl|CDD|378942
NZ_LT827010.1|WP_080127830.1|3438726_3441036_+|ATP-binding-protein	unknown	unknown	gnl|CDD|276809
NZ_LT827010.1|WP_014690122.1|3456789_3458682_+|acyclic-terpene-utilization-AtuA-family-protein	unknown	unknown	gnl|CDD|377804
NZ_LT827010.1|WP_014690126.1|3463261_3464452_-|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl|CDD|236709
NZ_LT827010.1|WP_014690125.1|3462125_3463268_+|acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|224871
NZ_LT827010.1|WP_080127833.1|3464647_3466288_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_043514200.1|3460252_3462124_+|acetyl-CoA-carboxylase-subunit-alpha	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NZ_LT827010.1|WP_014690111.1|3441037_3443986_+|NACHT-domain-containing-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	1.25881e-13
NZ_LT827010.1|WP_014690109.1|3435301_3438298_-|FAD-binding-protein	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.85387e-86
NZ_LT827010.1|WP_043514192.1|3434900_3435293_-|GNAT-family-N-acetyltransferase	gnl|CDD|235142	PRK03624, PRK03624, putative acetyltransferase; Provisional.	1.14919e-41
NZ_LT827010.1|WP_014690121.1|3456084_3456717_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.81399e-13
NZ_LT827010.1|WP_014690120.1|3455207_3455945_+|DUF2071-domain-containing-protein	gnl|CDD|378271	pfam09844, DUF2071, Uncharacterized conserved protein (COG2071). This conserved protein (similar to YgjF), found in various prokaryotes, has no known function.	1.122e-89
NZ_LT827010.1|WP_014690129.1|3467279_3468485_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.27547e-89
NZ_LT827010.1|WP_014690106.1|3431195_3433442_+|catalase	gnl|CDD|236886	PRK11249, katE, hydroperoxidase II; Provisional.	0
NZ_LT827010.1|WP_014690115.1|3447895_3450088_+|catalase/peroxidase-HPI	gnl|CDD|237891	PRK15061, PRK15061, catalase/peroxidase.	0
NZ_LT827010.1|WP_014690118.1|3453970_3454942_+|phosphotransferase	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.10015e-13
NZ_LT827010.1|WP_052311908.1|3458717_3460253_+|acetyl-CoA-carboxylase	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
NZ_LT827010.1|WP_172898757.1|3446301_3447315_-|ketopantoate-reductase-family-protein	gnl|CDD|224805	COG1893, ApbA, Ketopantoate reductase [Coenzyme metabolism].	8.25281e-38
NZ_LT827010.1|WP_080127833.1|3464647_3466288_+|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	7.64364e-93
NZ_LT827010.1|WP_014690112.1|3443982_3445359_+|hypothetical-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	0.00867227
NZ_LT827010.1|WP_080127830.1|3438726_3441036_+|ATP-binding-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.000229828
NZ_LT827010.1|WP_014690122.1|3456789_3458682_+|acyclic-terpene-utilization-AtuA-family-protein	gnl|CDD|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	4.36198e-165
NZ_LT827010.1|WP_014690126.1|3463261_3464452_-|putative-acyl-CoA-thioester-hydrolase	gnl|CDD|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	4.74003e-143
NZ_LT827010.1|WP_014690125.1|3462125_3463268_+|acyl-CoA-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	3.85241e-82

Protein sequences

>NZ_LT827010.1|WP_014690115.1|3447895_3450088_+|catalase/peroxidase-HPI
MSDIQDQKASGCPVAHDSATGHGGSESENPGIPSPQARTGGRPRGNRDWWPNQLDLSVLHAHSSKSNPLGEAFSYAAEFAKLDVEALKRDITEVLTTSQDWWPADFGHYGGLMIRLSWHAAGTYRIQDGRGGAGDGGQRFAPLNSWPDNANLDKARRLLWPVKQKYGQQISWADLLVLAGNVALESMGFQTFGFGFGRVDTWEPEEIFWGPEDAWLGDERYVSDKTMSEGVGATEMGLIYVNPEGPRGNADPAQAAHFIRETFARMAMNDEETVALIAGGHTFGKTHGAAVAADHVGPEPEGAPLEAQGLGWLSTHGSGRAGDTITSGLEVTWTDKPTQWSNRFFEILFGYEWELTTSPGGAKQWVAKDAEAIIPDAHDPAKKHKPTMLTTDLSLRVDPAYEKISRRFLEHPDEFALAFAKAWYKLLHRDMGPVSRFLGPWVPEAQLWQDPVPAVEHPLPGDAEIAQLKATILESGLSTADLVGVAWASAATFRSTDKRGGANGARLRLEPQRSWAVNQPVLPVLARLEEIQRSSTVKISLADLIVLAGVAGVEKAARDAGVEVSVPFKPGRTDATQEQTDVESFAVLEPRADGFRNYLRPGEKLQPEVLLVERAYMLNLTAPEMTVLLGGLRGIGVGATGSGRLTNDFFVDLLAPGTRWTASESEEHVYEVRDASTGDLLRTATAVDLVFGSNSQLRALAEVYASADARDRLVRDFVAAWTKVMENDLF
>NZ_LT827010.1|WP_172898757.1|3446301_3447315_-|ketopantoate-reductase-family-protein
MTPAAIPTGTDPRYVVIGAGAVGASIAAELHRAGADTLLVARGAQLAALRADGLRYVRPDGVHQVRIPVVAGPEEVELGEHDVLVLATKSQDTATAVRDWAWRPVKRADGATGLSATDLPLVTLQNGLDNERAALRSFARVVGGVIGIPATFVVPGEVVNHAADAPAVLFLGSYPAPASDPLAERIGAGLRRGGFRVHVVADIVAYKAGKLLGNMANTLDALYPESPLRDAALRTLQAEATAVLAAAGITPAALDLHEFRLGEIPSHPRVGASTRQSLARATPPETDYLDGEIVLRGRLHGIPTPAAAAIQARLHRALADGTPPGSLTDDDLARTLP
>NZ_LT827010.1|WP_043514195.1|3445327_3446296_+|hypothetical-protein
MRLNAAGRLLDDAAEPVPAARVREHLASRLRLPRSVTDIFVFVHGWRTPHRTAQSSFARFFGAVWNGRERWASLPGAAGPFVPWFIGVQWPSSSAPTPGGYQRIRERAHAVSTGGHAAFVLGQLLGYLDEQRDRPRRGADRLTNAAGQYVHCVGHSFGGRFLGEAIRRAADRPAGTLGWDHRSRHPFGVDTYLAFQMAAPPDIFDGRLAGILTDGVVHGRIVLTYSRLDHANAIWHRAMERRPGIGAVGATAPAGLVSTIPLHRPGDPYHRADFATPIVNVDASPVFTRPRLSVTGAHSDYWHAHSIHLLLSLAALARPTGG
>NZ_LT827010.1|WP_014690112.1|3443982_3445359_+|hypothetical-protein
MTADDLGMRRSVQNRLGGSDPFPGQRTPEPARLPLHRTIYLRLDADPDGSCRMTLMGDGLGDDGGGPLGGRLASTEKDLLAMADRLRKVWTDGFVLFLADDDVADDRCRFAADFDLSAHRDTPEWDAALRRLARTGYDVFRAVFLTGDAGLRRAGERLRDMLRAGPQVISFHSDVIFLPWQMLYVPPDGQDLLDDDCAWEFDGFLGFRHHVEHVFSDRPDSFRHRLDATGGIRAGLNYDAALDRMTPPVLRPLREMLESLPAERIERRWRETFPALDRALRADDYNDQIMYFNCHGWVTAAGPEEAYIALTDGRPIYKTHFREWLTGRPLVHSPVVLINACEGAQLSSMFLDSFGLALLAAEANCLIGPQIEIPASFAARYAVEFFRELLRGVSVGAVVRGLARGFAERHANPLGLAISSYRGMDTYFDVSNSADPAPATQRILLVSDDPVERRRTPA
>NZ_LT827010.1|WP_014690111.1|3441037_3443986_+|NACHT-domain-containing-protein
MSVTHFQQRRARLSRSLLPRGLPVLSVAAGLIGVALPSTSAATVLTGVAAALGAGAGVRAFAATRPGRPADAGEADSPAAQWKSYSEALIQPVPAQLPPGNSTFRGRAVELSTLRERHDRWRERQRTSQTEAPVLIFLHGMAGIGKTAVAQSLAHALKEDYPDGQLYANLGVAGTSRSPAQVLHSFLPALGWDVERIPTSTAERAWLFRTLTRDKRMLIVLDAARDQAQLRDLMPSESRCAVIVTSRRDMSPAFGARSLQLRPLSTDDGIDLLAAVLGYGVPFDLGAATAIVYACGGHPLALRAAADLAAQRRMSLPALADELREPGGLRAVLRAPSRDLHDRLSGQYKALGPDHQKAFRLLSFVGSDTFVPWVLRPASGVALPEAESLIADLASAQLVLAAGRDEVTAIDRYALPPIARQLAVSLAEPGDDPDGARRRIDEAYLEAAERVIRELDAGFAAARPASPVRWLPADARFAHRVAGRGQAKVWVREEYGNLLRVIRLAAERGDHALITRIASWLGGCAPRGVPAAEVLDGFRIAVDSAQHLGAAARADVLLARGAYRTAVERYTAAFEDFAEAQSLCRTGSLASRRVLLERRCGEAHLRAGEFTAAAGRFARAQELAARLPAGAAMLPLLRTLRRLADPDAGPPEPVEPVDPAGPGQPDDELAYWSALAGCDRAVAGDGWDTAERILAAAAADYHDDLRRAATIAYWQARLHLARHHRAPGSGHLRPALRAAHRSLHDHLLLGDPAGQVRTRCVLVSAYLAAGRTDLADRQLQEARRARAGVDPWLTRPGNPLDALLRRARAEAARHAGRDEEAVHELRRAALVLAANGDRRAVAEIAGLIGDDPAVLWRDAEAEAGSAGAVRAYLDHGPPITVGQAVTLRVEISAAHLRRYRDVVSGTSLTVLVCADGADVVPMGAAVDLRDLRDDVRLVHELRPRIAGPFSVKVQLYAPGDGVLLQEFEAGLAPVARAEREAA
>NZ_LT827010.1|WP_080127830.1|3438726_3441036_+|ATP-binding-protein
MWIRRLGAVTLVVMPVAFARIVSASAHSDGLFAWLALFAGYLVGVLGIGLAVVVSRQDGPRPPVPLVPRELPAVPPLLLGRADRVGEAVAYLSAATGPAVRTVVIAGAPGIGKTAVALFTAHRVAARYPDGQLFATLDARGRDPDEMVRRTLIRFLLALGHPAERAAGLDVCRQEFQRMSAGKRLLVVLDDVHGLDPQPLIPAGAGSAVLLTSPQVRPGRAPHLLLPLEPLADRDAVALLAQIVGEQRVRDSLPAATALARACAGLPLALQIAGQALVARPSADMSVVLSRADVASGDSRPTERGRDPRSVEPGHDPRRWALNVSYELLSRGDRDAVLSLGRLSRRFEPWMLAAETNLDEDQARSLADRLSATQFVERWTADAAGVPVYETVEHVQDFARLRAGGDRPAPPHPRPRTRDPLDEQRIHTYDLLDKGSLVAADVNVREVLDRARQAGDQPGVGKALAALAELRAELGGTDEVVDLAEQAWQHQDPGIRARVYRVMGHIQRRVRQLDVAERNLSRALRHAGQAGDEPEQIRVLTELALVHRLGGRAAQALEHTGRAMALAEGRRDGGIRYRSRILLAEGMTLIKLSRYAEAEQRFADARAAADRAGYRLWRQWVDYRDAQLHVRSGDAVRAQDLAIAALAGFTGIRHRYGTGHCRLLLGRIHADAGQYAAARTVIEDALETFRNCGDRFIEGHAAAELASVHLREGSLAAAADALRRAKQLKTGQRYWQTSLRLTGARLRRMAGGGAPRRVEPIAPSSPVGW
>NZ_LT827010.1|WP_014690109.1|3435301_3438298_-|FAD-binding-protein
MTTAALSTDLVRSLNQAGVTDVLTDPAHRSAYASDASLYRVVPRAIVRPRHDEDVAATLRVCRERGVPITARGAGTSVAGNAIGPGVILDFSRHLNRVLEVDGDGRWARVQAGTVQATLQAAAKPFGLRFGPDPSTHTRCTIGGMIGNNSCGSRTLGYGRTSDNVLALKALTIDGEQLVTGPVTTGADKTVAALKDLIGAHLAVGRTEFGTFGRQVSGYAVEHLLPENGFNLTEFLVGSEGTLAVVTEATVRLVADPVHRTLVVLGYPDFGTAGDVIPAILEFKPTACEGLDHRICDVVRSRRGPDAVPPLPGGAAWLMVEIAGDDLDEVRERVAGLVKAAQAVDSLIVEDTAQAAPLWKIREDGAGLAGRAPGGLPAHAGWEDAAVPPARIGAYLRDFDALTARHGLHAMPYGHLGDGCVHVRLDFPLDKPGGPGRFRAFLEDAADLVVSYGGSLSGEHGDGRARSELLSRMYSPAALDLFRRIKHTFDPDNLLNPGNLVDPDPVDANIRVSQARPVTTKLALAYHADGGDFNQAVHRCTGVGKCRVDTTVLGGVMCPSFLATRNEKDSTRGRARVLQEMLDGDLAPDWRAEAVHDALDLCLSCKGCASDCPTGIDMAAYKSEVLHQSYRGRARPRSHYSLGWLPRWSRLASRVPALANLMTNLPGIRRLALYVAGVDARRSIPTFADRTFRSSFRGVQTGKPVILFVDSFTDHFAPDIARAAVDLLTDAGYAPRVTSRTACCGLTWITTGQLDAARRILGATVHELHQAVKQGIPIVGLEPSCTGVLRQDAVELVDTEAAKEVAAATRTVAELLAATPGWTPPSLAGVRVIAQPHCHHHAVMGWEADAKLLKRAGATVKRLGGCCGLAGNFGVERGHYEVSVAVAEQQLLPALAAAEEGDIFLADGFSCRTQADDLAKVSGLHLVQLLADALPANRSAATTGDSGTGLAGAGDSAPGAPAPGASAPGASASGASAPGASASGASAPGHEARLGDEE
>NZ_LT827010.1|WP_043514192.1|3434900_3435293_-|GNAT-family-N-acetyltransferase
MRSFEGADYEPVAAVWAAAGAGVLSRDELTRKLTRDPDLFLVATDGPELTGAVLGTWDGRRGWIFRLAVHPDHRRRGIATALVRELESRFRALDCPRINLLVLPDNEAGLRFWQDLGYLPAPDVLCTKPL
>NZ_LT827010.1|WP_014690107.1|3433721_3434747_-|hypothetical-protein
MVEWGMLLAPLLVAAVNAAPVCRIADKRMDELSGLVTTADGYVVVNDGSDEASHRRIFYLRKDCSVARAVSYPSRPRDTEDLQLGRDGILWVADIGDNGRSRDTIALWRLTPGSSKPQLLRMSYPDGAHDAEALLITAEGSPIVVTKEPGAAGIYVPDGGLRATGTTRLKRAGDVSVPFTSTSNPFSLAGRLLITGAATSPDGSRVVLRTYADAFEYDVPGGDVVKALVSGTPRQIPLPDEPQGESVAYTTDGTALLTVSEGAKPPILRHPLPDTPATPRSPASSTADQAAPSAAVPPAAAEAVRATPKSSSSRLPLVLLLIAATALCLAAAIAAARRRKR
>NZ_LT827010.1|WP_014690106.1|3431195_3433442_+|catalase
MEARSPAEVIKDAVTAVTSEKKPDVPGAPGSGTPTVEEPATPREPLPPKPEQGQPDTRTPTGAPTGAPPTAYGQQGPYLTTAQGARLRDTDHSLKAGPRGPILLQDHHFREKITHFDHERIPERVVHARGAGAHGVFTSYGTAAALTQAGFLKEKGKQTDVFVRFSTVLGSRGSADTVRDTRGFATKFYTDEGTFDLVGNNMPVFFIQDAIKFPDIVHAAKWHPDREIPQAQSAHDTFWDFVSLHTEAQHHTMWNMSDRGIPRSYRTMEGFGVHTFRLVNDAGETVLVKFHWKPKLGVHSLVWEEAQITNGVDPDFHRRDLYDSIEAGAYPEWELGLQVFPDNPEETFAGIDLLDPTKIVPEELAPVQPVGKLVLNRTPTNFHAEVEQVAFHLGNLVPGIDVTNDPLLQGRLFSYLDTQLTRLAGPNFHQIPINAPHAPVNDMLRDGFHQHAVHAGVAPYRPNSLDGGNPFTTTEGSFVDVPVVVTEAPKIRDLPVSFKDHYTQVRLFWQSMTPVEREHIIRAYTFELGKCYHQAIKERQLQCLANIDPVLCEQVALGLGLPAPAPSIDLPEVTPSAALSQIGQQWPADGRIVGIVVDETGGDAAVAEIREAIAAAGMVPLIIAPHGGKVGGLTVQRTFATARSIEYDAVLVAAAPVPAPDAVPARDEKAGAPRTAAVDPRVNMLVDEAWRHAKAIGGWGTGADLLRRTGLADTPGVVVGDSATEVLTALQQLMANHRVWERFPATVA
>NZ_LT827010.1|WP_014690118.1|3453970_3454942_+|phosphotransferase
MESITKNRQSPDVLRAMVERAYGRAEVPAGDDWYVELSHGWFNVAYRIRLRSGHRTVLKIAPPPGVEVMTYERGAMATELAALRLIREHTDVPVPEVEFVDRSHELCDADYFFMAFIDGDNLGMLRGQQSPRERAAYNLSLGEINRRLNAIRGERFGPLDGSGDPSWRVVFTAMIEGVLRDGERRDVPLGFGYDEVRAVIAAHAGSLDEVTEPRFVEWDMWDNNVMVRDGRVVAIIDHERAFFGDPLIEAGFTGSEVPAYGDSSAFIQGYGRGPATEAERIRRRLYCLYLALIMTIETAYRNFPGTGNYDWASERLKETMALF
>NZ_LT827010.1|WP_014690120.1|3455207_3455945_+|DUF2071-domain-containing-protein
MDVEEITSETVRPVARAVLGQRWTDLAFLHWAVDPDRVAPLLPAGTVPDVIGGVTYAGVIGFRMERIGFLGSPGVPYLGTFCETNVRLYSVDAQGRRAVVFRSLEAERLIPVLVARASLQLPYMWARMRIVRDGDELAYVSRRRWPGPRPATNRMRIRVGAPIAEPSPLEDFLTARWGLHTRAWGRTRHLANDHPRWPLHRAELLDLDDSLLAAAGLPGIDTPPVSVLYSPGVPVVFGPTGRVSR
>NZ_LT827010.1|WP_014690121.1|3456084_3456717_+|TetR/AcrR-family-transcriptional-regulator
MGRSRTNPAPTAPVTARGRRTRDALLAAGRELLETRGWPAFTPEQVAAAAGVSYGTFYTYFESKDDLLGAIVRAVAEEMFTDSLVAPDTADDPYVRIVASNRGYLRAWRNASRVLRLVEQGAAADDTLRQLLLEVRERYVHRGAEGLRRLQEAGLARTDLDPRLTAIVLGAMVEQMAHVIYSLREPLDEEVVVSHMSKLWAAAIGLRGHP
>NZ_LT827010.1|WP_014690122.1|3456789_3458682_+|acyclic-terpene-utilization-AtuA-family-protein
MRTIRVGNCSGFYGDRLTAMREMLEGGPLDYLTGDYLAELTMLILGRDRQKNPDTGYAKTFLRQVADCLSLARARHVRIVANAGGVNPGALAGAIRALDPTVRVAHVAGDDLLTGAFPGALTANAYLGAFGIAEALRSGADIVVTGRVTDASLTLGPAIAAFGWRRDEYDKLAAGIVAGHILECGTQATGGNFSGFATIDTSRPLGFPIAEIDDDGAVVITKHPGTGGAVTEDTVTAQLVYEIDSPRYLNPDVTARLDTIRLAAPEKDRVAICGVRGEAPPATTKIGITRLGGYRNTVSFVLTGLDIEAKAAWVREQFESGLGRRPETLVWDLIRTDRPDPGTQAEGAAVLHCHGKDADPDVVGRPFSGAAIELALASYPGFHVTGPPSGATPYGVFEAAYLPQGEVPHVVVLPDGVRVEVAAPGWERAGVSAGSGRPGRVVSADGVHAGPPASERGDVVHTGGLSTGDPHDRGVGDDTGSGMVPLGGRAVVDGGQRSHPTTTEPPNHPAPDGYRHHTRAPLGHLLHARSGDKAGTANLGIWIPAAHPHRLAAFRWLTRWLTADRLRTLLPESTPFPISLHPLPNLCALNIVIAGLLGDGVAASTRPDPQAKALGEWLRSRLADIPTELL
>NZ_LT827010.1|WP_052311908.1|3458717_3460253_+|acetyl-CoA-carboxylase
MLERVADLERQHAVAVAGGGPKAVERHHRRGKLTARERIELLLDEDSAFLELSTLAGWGTDVTVGGSVVTGIGVVEGVECMIVANDPTVRGGSSNPVTVKKSFRAAQIAAENRLPTINLVESGGADLPTQKDIFIPGGRHFRGLTEASADRRPTIALVFGNATAGGAYVPGMSDYVVMVAGGAKVFLGGPPLVKMATGEESDDESLGGAQMHARTSGLADFLAVDETDAIRIGRQIVRRLNWRKLGPPPRAGYAEPVLDAEELLGLIPSDLKVPFDPREVVWRIVDGSEFDEFKPLYGTSLVTGWARLHGHPIGILANAQGVLFSAEAQKAAQFIQLANQADTPLLFLHNTTGYMVGKEYEQGGIIKHGAQMINAVSNSRVPHLSVVMGASYGAGNYGMSGRAYDPRFMFSWVGAKSAVMGPAQLAGVVSIVSRQAAAAAGRPFDEEADARTRAAIEAQIERESLAYFTSGMLYDDGVIDPRDTRTVLGICLSVIHNAPVQGARGYGVFRL
>NZ_LT827010.1|WP_043514200.1|3460252_3462124_+|acetyl-CoA-carboxylase-subunit-alpha
MIRRLLVANRGEIARRIFRTCRNLGIETVAVHREEPDLHVREADIAVAADFLDAEQIIDAARRAGADAIHPGYGFLSENADFARRTEAAGLIWIGPDPDAIAAMGDKIRAKKLVAAAGVPILGGDADTYPLLIKAAAGGGGRGMRIVTDPGTLRSELAAAAAEAQSAFGDGTVFTEPYLPRARHVEVQVLGDRHGRIWIVGDRDCSVQRRHQKIIEEAPAPLLPDDVRAALHRHARAAAEAVGYRSAGTVEFLVDGDRIFFLEMNTRLQVEHPVTEAVTGLDLVAQQIAIAEGHALPPAPPPITGHAVEVRLYAEDPAAGFAPQTGELRAFDFAAAGVRVDSGVEAGSRVGVRYDAMLAKIIAYGPDRPAALRLLADALRRGRLHGLTTNLPLLRAILADDDFAAGRLDTALLDRKLAAWTGVGQDHAVRKAALAAAVGSAVRTAGSANVQARIPAAWRNVPSAARVRTYRCLDREYAVTYTARCGRIESSWLPGVGVVSVDGDRVVLDDHGVRETYRVTPHAGGADVHGPAGPYDLLTVPVFGDPAATLAAGSLLASMPGLVVAVHVGEGDRVAAGAPVVVLEAMKMQQTLTAPADGVVTALSAAVGRQVAAGDVLAVIDGS
>NZ_LT827010.1|WP_014690125.1|3462125_3463268_+|acyl-CoA-dehydrogenase
MTAFVESEERRELRGAVARLGRKYGEEYFYAAAREGRKTTELWQEAAALGYLGVSIPEQYGGGGGDIGDLAAVLEELATAGCPLLLMVVSPAIVGTVIAQFGTAEQQRRWLPGLATGAATYVFGITEPDAGSNTHQIATRARRDGDDWILSGTKTYISGVDEASYVLIVARVGKRPSLFMVPVGAPGFTYRRIDMGLVAPEDQFTLFLDEVRLPADALIGSEEAGFDQLFAGLNPERIMAASSATGMARWALRKAVGYAGDRAVWGVPIGTHQAISHPLAKLHIEIEAARLLTQKAAALHVAGELKAAGEAANMAKYAAGEAVCAAVDQAIQTHGGNGLATEYGLVQALATSRLTRLAPVSREMALNFVAQFSLGLPRSY
>NZ_LT827010.1|WP_014690126.1|3463261_3464452_-|putative-acyl-CoA-thioester-hydrolase
MKAVLLMLAGLLAAPGTPARPVLSAAEAAPYTAANYLGFSGTYAHPVADPWRPTPIRTPRRPDLVVGGRAGLPDVQQAVNAAYRAGGTRRLAIAVRPGTYPGTVFIPAGTPPLTLYGDGPADRVRLQFTVDATSTPAQWAAQVNATGRYAEGDPAWPMFQSCATRTTATVGLCATVVWAQSTDLQLRGLTITNTLLDTVDRGTHQALALRTDADRTQLQDMRLIGRQDTFLANANDVTSIARVSVRRSYVEGDTDFVFGRAAAVFDHCTFRLVSTRKPAGGVIFAPNTDPHFRYGFLVTRSRLLTDAAYRAAPTGHLGRAWDQGAGATGYLPGVTPNGQLVIRDSHLGAGFDTAAPWAPAATTSRPFQARVDVGRDLDDVAANRLWEYRNHGPGAQ
>NZ_LT827010.1|WP_080127833.1|3464647_3466288_+|serine/threonine-protein-kinase
MSGWQPTGYTPVRALGAGASGSVVLATHDATGTPVAIKHLTGQISDDAAFRAAFRQEARLLGEIDDPHVCRLYEYVESADGAAIVMELVNGVSLRQMLREHGPGTPEAALCVLKGSLSGLAAAHAHGVVHRDYKPENVLVTGDGRSKLADFGIAVPVGQGAATVVSGTPRYMAPEQWTGGAVTPACDIYAATATFFECLTGHPPYDGANLFALHDQHAHAPIPTGATPEPVHDLLRRGMAKQPADRPPHALAFLDLLERVAGAAYGPDWEDHGLRDLARRAALLAALWPFPDGSSGATSVATTTFGSSAVSPARRLRRGRRTTALAAGALVAAVLLGGAGYHFAVADQHTALADETPAPATGGPPAADPSPSAAPAVSGPAVTGGSAAPSASPSRSARPGATPTSATPTTSATPTTRPSPSPSVSTTPPDATAPAVGPADTTYTVLDPAGCPYGVRSTTITATVTDDRSGPAALKVSFRYPLGRATSTVAMSSAGRNVFRGTLGPLPMPNATTRIPVTVVAADAAGNAGSAAAPVYVTLDNYCTPG
>NZ_LT827010.1|WP_014690129.1|3467279_3468485_+|cytochrome-P450
MTDTVPAYPFAHPAALDPSPEWEQLRNECPVARIRLVSGDEALLVTRYDDVKGLLADPRFTHSLARPDAAKISASDDGGVFNREESAMIASPDHPRWRRMMNRSFTVKRVTAMRPRIEQIAHRLIDEMVAAGQPGDLQSALGFPLPVFVICELLGVDPGYRDTFSHWSDAMLNLTRFDQAELTKAAVEFQEFMAQHVRDKRAEPGDDLLSELAAIVDSQDGRMTETELVLTAQGLLVAGHETTANMIGKMVAMLLADRPARWERLVADRGLINSAVEESLRFDANPGIGLPRYISEDIEIAGCPVKAGTVVMASMAAGNRDETAYEQAGEMRLDRSPNPHLSFGAGPHSCLGQALARTELQVTLAVLLDRLPTLELAVPPEELRRRTGLIVGGLEEVPVRW

Crispr_ID: NZ_LT827010_11

• CRISPR_ID: NZ_LT827010_11
• CRISPR_location: 4385709-4385823
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_11

Consensus_repeat	Method
CGGGTTCGCGCCGCCGTCGGCCGGGCCCTCG	CRISPRCasFinder

spacers of NZ_LT827010_11

>11.1|4385740|53|NZ_LT827010|CRISPRCasFinder
TCCGGGGTGCCCTCGGTGTCGGCGGCACCGTCCGCGCCGCCGTCGTGCCCACC

CRISPR arrays and Neighbor proteins around NZ_LT827010_11

CRISPR arrays

The CRISPR arrays of NZ_LT827010_11

>merge|NZ_LT827010|11|4385709-4385823|CRISPRCasFinder
CGGGTTCGCGCCGCCGTCGGCCGGGCCCTCGTCCGGGGTGCCCTCGGTGTCGGCGGCACCGTCCGCGCCGCCGTCGTGCCCACCCGGGTACGCGCCGCCGTCGGCCGGGCCCTCG

>NZ_LT827010|11|9|4385709-4385823|CRISPRCasFinder
CGGGTTCGCGCCGCCGTCGGCCGGGCCCTCG	TCCGGGGTGCCCTCGGTGTCGGCGGCACCGTCCGCGCCGCCGTCGTGCCCACC
CGGGTACGCGCCGCCGTCGGCCGGGCCCTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_085945578.1|4383285_4384458_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
NZ_LT827010.1|WP_014690933.1|4384509_4385676_-|cupin-like-domain-containing-protein	unknown	unknown	gnl|CDD|369647
NZ_LT827010.1|WP_043511724.1|4382681_4383173_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690944.1|4393225_4393642_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690927.1|4380002_4380518_-|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_LT827010.1|WP_014690937.1|4387660_4390291_+|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl|CDD|319775
NZ_LT827010.1|WP_155123558.1|4390299_4390728_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690936.1|4387191_4387650_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_052311642.1|4377371_4377989_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043511722.1|4376540_4377152_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690926.1|4378782_4379823_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043511727.1|4391137_4392187_+|YbdK-family-carboxylate-amine-ligase	unknown	unknown	gnl|CDD|237408
NZ_LT827010.1|WP_014690939.1|4390724_4391141_+|RDD-family-protein	unknown	unknown	gnl|CDD|377640
NZ_LT827010.1|WP_043514748.1|4392540_4392972_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690929.1|4382091_4382388_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690928.1|4380653_4381610_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|153232
NZ_LT827010.1|WP_014690941.1|4392260_4392536_-|SHOCT-domain-containing-protein	unknown	unknown	gnl|CDD|378276
NZ_LT827010.1|WP_014690943.1|4392989_4393217_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014690925.1|4377985_4378657_+|DUF4166-domain-containing-protein	unknown	unknown	gnl|CDD|379359
NZ_LT827010.1|WP_014690935.1|4385956_4387126_+|cytochrome-P450	unknown	unknown	gnl|CDD|225035

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_085945578.1|4383285_4384458_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.25232e-06
NZ_LT827010.1|WP_014690933.1|4384509_4385676_-|cupin-like-domain-containing-protein	gnl|CDD|369647	pfam08007, Cupin_4, Cupin superfamily protein. This family contains many hypothetical proteins that belong to the cupin superfamily.	4.06502e-33
NZ_LT827010.1|WP_014690941.1|4392260_4392536_-|SHOCT-domain-containing-protein	gnl|CDD|378276	pfam09851, SHOCT, Short C-terminal domain.	0.00808069
NZ_LT827010.1|WP_043511727.1|4391137_4392187_+|YbdK-family-carboxylate-amine-ligase	gnl|CDD|237408	PRK13517, PRK13517, glutamate--cysteine ligase.	1.87144e-80
NZ_LT827010.1|WP_014690939.1|4390724_4391141_+|RDD-family-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.76505e-14
NZ_LT827010.1|WP_014690927.1|4380002_4380518_-|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	3.22568e-31
NZ_LT827010.1|WP_014690937.1|4387660_4390291_+|HAD-IC-family-P-type-ATPase	gnl|CDD|319775	cd02080, P-type_ATPase_cation, P-type cation-transporting ATPase similar to Exiguobacterium aurantiacum Mna, an Na(+)-ATPase, and Synechocystis sp. PCC 6803 PMA1, a putative Ca(2+)-ATPase. This subfamily includes the P-type Na(+)-ATPase of an alkaliphilic bacterium Exiguobacterium aurantiacum Mna and cyanobacterium Synechocystis sp. PCC 6803 PMA1, a cation-transporting ATPase which may translocate calcium. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LT827010.1|WP_014690928.1|4380653_4381610_+|helix-turn-helix-domain-containing-protein	gnl|CDD|153232	cd03138, GATase1_AraC_2, AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain. A subgroup of AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain. AraC regulators are defined by a AraC-type helix-turn-helix DNA binding domain at their C-terminal. AraC family transcriptional regulators are widespread among bacteria and are involved in regulating diverse and important biological functions, including carbon metabolism, stress responses and virulence in different microorganisms. The catalytic triad typical of GATase1 domains is not conserved in this GATase1-like domain. However, in common with typical GATase1domains a reactive cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.	1.0382e-50
NZ_LT827010.1|WP_014690925.1|4377985_4378657_+|DUF4166-domain-containing-protein	gnl|CDD|379359	pfam13761, DUF4166, Domain of unknown function (DUF4166). This domain is often found at the C-terminus of proteins containing pfam03435.	1.70239e-58
NZ_LT827010.1|WP_014690935.1|4385956_4387126_+|cytochrome-P450	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.23985e-29

Protein sequences

>NZ_LT827010.1|WP_014690933.1|4384509_4385676_-|cupin-like-domain-containing-protein
MTTSALARAVGIGEAEFADTYWGKQPLLSRGRAGFTDLLSVPAVDELLSRRGLRTPFLRVAQHGKVLPAGRYTGGGGAGAEVGDQVHDERVMRLFAGGATLVLQGLHRLWPPLIEFTGRLGAELNRPLQVNAYLTPPGSQGFATHYDTHDVFVLQCEGRKRWIIHPPVLSDPIENQPWGGHADEVAATAEGTPAIDTVLEPGDALYLPRGWLHSARTEQVRSLHLTVGIRSLTRYALVEELLAMAVQEPRLRATVAYRRNPESELTATIEALREWLPTVDPAAVAARMRERTGPATRPAPLSPLAQLDFAERLTDTDEVTARPGLSVDVDGGTVRAAGYTVTFPGYCEPALRLVLDGKPHTAGDLPLDRDDSLVLIRRLLREGLLTPA
>NZ_LT827010.1|WP_085945578.1|4383285_4384458_-|hypothetical-protein
MRRVLWRRARGSGSNLYRSGPLGRTAWGTYQLPGILAAAGVVFWLLLRRAGKATRVDRAAKYMDRGRNIDALTTGAAATAKRLGVTTSVGLPLGAALAGGQTLRMSWEDVAVHVWGPPTRPPTTRSPRPWSRCAKWNSRKRPPAPRGPARREQPRRVGRPRRPRPGRRRRPTGHRADAGTGRGDRRSVALARPGRRGTGCTKSDSAADRPDRRQGGHAGRRPGRRRPRPAAHQRRGIGRRGADHGRRHAEPVLPEPSPKWAVWLLNAMNPLQAASALAGMDSALTARLLAEMQPRPAARVLAAMESDRAGSLMETMALRTPHKAVPLLTAMDMTKVFDLVNATAPSLRSRIMQATGLRQVPALPTETDRNTAHLIVAALAELHTERPGLT
>NZ_LT827010.1|WP_043511724.1|4382681_4383173_+|hypothetical-protein
MGAEVEPFQALQASLSQYFDGDFDAALAEDESAALADADRIIAEHVRTAQVRLARAAPALDWSDHTTLTEALPAIARRAADLRFVQILGTPAPTVTITVDHQPAETIPRAAARHDLDVNTLTSAVRRANLSPATRLDARTPLYRTDGIDRLLRSRRPRQNPAP
>NZ_LT827010.1|WP_014690929.1|4382091_4382388_+|hypothetical-protein
MRIRTAVAVLALTAGAAAGSLALTGPAMATPQNGLVNVYVQDVASGNQVIALQNVPVDVAANVCGLTVNVLSTELLSGNHAVCTAKNTPTTKSWVSYS
>NZ_LT827010.1|WP_014690928.1|4380653_4381610_+|helix-turn-helix-domain-containing-protein
MKVAVLVYDGVFDSGLAAILDILDGANAMGHEIGGAPTWDVRTVGVRPQIRTGAGHLVVTESLARAEEADLLIVPALAERRPEMLLAHVGGAASRPVRDQIARSRERGTPVASACTGTFLLAEAGILHGRRATTSWWLAPVFRARYPHVEVDQSRMVIASDGVTTAGAAFGHVDLALAVVRAGSPALADLVARYLVVDERPSQSAYTISSALAQSDPTVAAFERWARGRLADPITIADAAKAIGVSNRTLQRCVQRTLGTSPIRFIQDLRVERASHLLRTTELSLESIAHKVGYEHPNTLRVLLRERTGKTTTALRGS
>NZ_LT827010.1|WP_014690927.1|4380002_4380518_-|PaaI-family-thioesterase
MTTNLDSPRSRTHTWRQPLPWAQLGDLSGRDLLQKILDGEVPEPPITGTLGFRLTEIGDGTASFEGDPGEHLLNPMGTVHGGFLATLLDSALGSAIATQLPRGRVYTTMQLNMHLVRPVLTDTPRLRCDAVTVHVGRTMATAEARVVDVAGGKLYAHATTTCAVIASSRPA
>NZ_LT827010.1|WP_014690926.1|4378782_4379823_-|hypothetical-protein
MKRRNVLAAAVVAMTSVPLTATRAMAAQTQVETPAEAENTFVRWLSTQDPRAMIRSRARAAILSTPAERTTFLAETYTRVLPDIALTRARQTDYATRMVRTHPAIYYPWVNATGLRALDGAEARIREFSSTDYTAALTKDRDKVPFDTGAAGVVAEDRAFVAELAVSGLSPVARERAARAVTAGTDADIAEFLLYRWAISAEVDIELFRTDYVAAEFGWWTDVRKAVVAAESAEQLARDAVGDAAEPARAAAVRAWEAVGAQAATALAGWAAHQRFTQVQIDDWQRTATTAAASTSPTWRLLKVDAPAVRKLWLAEQANAAARTAWWTAVNENARARVAALTTPAV
>NZ_LT827010.1|WP_014690925.1|4377985_4378657_+|DUF4166-domain-containing-protein
MTSVFQHALGDDFGRLHPRLQRRFGVDGERDQGCVGTGVMERVWRGGAYTAPFLHLGTLRHILFPETGAGIPFTIENYAYRDTYGRPTLTFVRTFQVRPHRRRRFDATMVYHPGRDVIVDYLGTTQHLAVDLDVSVDATGALHLRSGPQLFRGGVGCPRFLTGDAEVHEWWDERAERFHIRVKVTNRHFGPLFGYHGTFTTAYVPSGAPVPAAVRPLREACPR
>NZ_LT827010.1|WP_052311642.1|4377371_4377989_+|hypothetical-protein
MDRVWLATQDHRQHPRWDARFGRIDPVPGSTPAAFTYATAVLPGVEIAGYGVHSGERQQAGGAVSALRFGSADRRSPIQEGSGYWRYVPVPGGVRFLTGYTYRTRWGRAGRLVDLVFGPTFGWATAWSFDRLRLWLEHGITPERARLYTALELVLRAALVATAGLLDGRPAVVLVAALLAIGLPPHPHTPAARRCRRRPEQENPR
>NZ_LT827010.1|WP_043511722.1|4376540_4377152_-|hypothetical-protein
MPGPGRDPALPLPRRRRHTPIPARDRSLDRPRLRRATLLDPRPRCRRRDLAQLARPGRRTVAPGPKPGPATGHPAHPGATVRKYRDSTPRWDVPDWALLSGSRTVAGLALIAAGEDDTEFAYASSNFWSNLHHSLCRANPTPDWPLLTRFRRLEDTARHRELTRLHTEPDATEVVRSELAAWSPHEPVLRAVATAIVDAVTRR
>NZ_LT827010.1|WP_014690935.1|4385956_4387126_+|cytochrome-P450
MLLDDSVGLAVQGYGWLPTVWRRAGGGPVVQTRLLGQKVTALRGPEAVRFFYDESHIRRHGALPEPVQGTLFGKGAVHTLDGDEHHARKAIFLNVLKDPRHIADLVDRAGRAWDETAAGWTPGRPVVLFDEASRVLTRAVCDWAGVPVSDAEVPRVAADLTAMVDGFATLGPRHWRARTARGRRERWLEPLLGHSWIRGLDAVDMLNILRPTVAVSWFVAFAGHALHRWPRQAEPLRDGNTAYAIAFAHEVRRFYPFAPFVGGRAVRDLSWGGHDIPAGSMVLLDIYGQNHDADLFPEPYRFNPARFLGISPQADELIPQGGGDAATNHRCPGEDVVVMLLADLATRLARCDYSVPEQDLTIPLTRIPARPCSGVVLVPAAAEVFTPAG
>NZ_LT827010.1|WP_014690936.1|4387191_4387650_+|hypothetical-protein
MSSEPVKPSVNAGKLWAGGGATAAVAALIAVAGILLGRGIFDIGVLAPKGDGAWGDASTGWYALGAAVAALAATGLVHVLILTTPRPMRFFGWVVGLATVSAMLAPYVTDAERAAKVYTSGLTMILGIAIGSLIAGVARSATTLVRPRPSYR
>NZ_LT827010.1|WP_014690937.1|4387660_4390291_+|HAD-IC-family-P-type-ATPase
MTATYHVLTVPEALEAENVDQQRGLSGAEADARRQKFGPNRFAEAKREPWWRSFARQYADPMQLVLLFAGLGSLYPLKQWGTGVLLLALTLLNAALGLHQEGKAAAAIDALQKMMIVKARVRRDGTLIEVPAEDLVPGDVVQLEAGDVVPADGRLLRAATLEIDESALTGESLPVAKNVEPLAEADVALGDRSDMAYMNTNVTRGAGELLVTATGMGTEVGRISKMLATDKGADTPLTRQLAKLTNQILIISGIALLASVLINLARGNEFTVVFTAAVAFAVSAIPTGLPAVVTTILSQGTQLLAKANAIVKRLRSTETLGSTSAINSDKTGTLTLNQMTAIEMVIPGRRYVVSGSGYSTQGSIKRVAGEPDTPLEEFLLPMILASDAVVTDGSMIGDPTEGALVVLAEKGGLDAQATRERYPRIAELPFDAAYKLMATFHEMSGKIRCYVKGAPDQLLARSNVTPDQRERYTAENDRLARQGLRVMATAYRDFDRLGDDLLESLQDLTPLALVGIVDPPRPQARDAIEQAHAAGIEVRMITGDHAVTAAAIAGRLGIRGRAITGAEFAAMSDEEADREIGGIGVIARVTPEHKVRLVEVLRRRGHIVAMTGDGVNDAPALKKADIGIAMGITGTEVSKEAAAMILTDDDFATIVKAVALGRALYANLKKYIFFQMGTLVGMIITFLVASIGNIAAGVPFVPLQTLWLNFTTQIFQSVGLGYGKAEADIMSHPPRRSDEPLLSRAALGWLGILGLIMGAVTLVVIGWADHGHDVDYARTMGLTAFSIANLAFSLTVRSDIRSVFSLETFGDKRFVVTTGLSAAAIVLATEFGLFQKILHTSSLGVRHWLICLLAGVVVVIPTEIRKAVLRRRNGSA
>NZ_LT827010.1|WP_155123558.1|4390299_4390728_+|hypothetical-protein
MDIAIGAAFRAGEKSADTIGTLRSRLDKESLRTASELWARWTLLAERGAAERERGRRGAQRAVDAAVERLVHSEVVGRVVDAQLERVLTLLENEPDRIRALIRGQRESIVGEAVGRVRAGAAAGDIAVDRLTLRMSRRGETA
>NZ_LT827010.1|WP_014690939.1|4390724_4391141_+|RDD-family-protein
MTGYAGLVSRTLAYLIDTVAVAALTGAGVIALGVVASVVGSEARDLARFVLSSYLVFLPTLLALYCALFWGLAGRTPGMALLGVRVVRADGAPVRWPAALVRALLLAYFPIGALWLIVDRRHQGLPDKIAMTAVVREG
>NZ_LT827010.1|WP_043511727.1|4391137_4392187_+|YbdK-family-carboxylate-amine-ligase
MRPVLTIGVEEEFLLLTADGAVSPTAAAAVRHARLPEQIKPEYMAYQLETSTRVCETLDELRRDLTRLRLIAADAAERDGALLVATGSAPLDGGPRQALTDDARYRDLARRFPDATAAGGTCGCHVHVGVPDRELATAVLTRLRPWLGALLSLAVNSPYSGAADTGWASSRYPAQLRWPTCRPPGVWPSADRYDAAVRDHVDAGMATDAASVYFWARLSPRYPTIEVRIGDTGLDVADSVLLAGVVRALVAALLDDVRRGEKIVPVASARVEADLELAARGRLGHGRRLLEKITPYLAGDVGEVYAGFERLRREGTGADRQRRLWARHSGGAGFVRWLAHATTPLAVAY
>NZ_LT827010.1|WP_014690941.1|4392260_4392536_-|SHOCT-domain-containing-protein
MPGLLRGIARTAVIAGTATAVSNRVSRRQQGRWARHDAEDQYLAEQEQEPVDQEDPMTAKLDQLRRLADLKAEGLLTDAEVEVQKSRILHS
>NZ_LT827010.1|WP_043514748.1|4392540_4392972_-|hypothetical-protein
MGPVDYLCIEFPKGGLRGRALPMLLDLVDRRVIRVLDLLFVRKSPDGTVVALDGRELQLNGLGAFHGAASGMLGGDDLREAGQILQPGAAAALLVYENLWAAPLARELRESGAQLVAGGRIPIQELLAALDATEAAAAPAGGR
>NZ_LT827010.1|WP_014690943.1|4392989_4393217_-|hypothetical-protein
MTRRQIARRRAADAYDVLLGRPVRPGYGMLVVVPLFAAAGGALIGLGVDILVTQRRTAAATAQPAPSPRLEPVSA
>NZ_LT827010.1|WP_014690944.1|4393225_4393642_-|hypothetical-protein
MALGPLELMIMSFPADRLNDGVLTTLDRLTRAGEMRIVDVLVVRADAAGVACTVELCELPGLSGDLAWARLATGLITATDVEEVARLADHETDVLAVLLEHRWVNDLAGRVAASRGTIVALNHIPGAPGHGRVLTSTR

Crispr_ID: NZ_LT827010_12

• CRISPR_ID: NZ_LT827010_12
• CRISPR_location: 5588482-5588702
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_LT827010_12

Consensus_repeat	Method
GGGCGGCGGGACGATGCGCTGCCGGGGCG	CRISPRCasFinder

spacers of NZ_LT827010_12

>12.1|5588511|19|NZ_LT827010|CRISPRCasFinder
GCGGGATGCCGGGCTTTCA
>12.2|5588559|19|NZ_LT827010|CRISPRCasFinder
CCGCGATGAATCATCGGCC
>12.3|5588607|19|NZ_LT827010|CRISPRCasFinder
ACGGGAAAACTCGTTGCCC
>12.4|5588655|19|NZ_LT827010|CRISPRCasFinder
GCGGGACGATGCACTGCCG

CRISPR arrays and Neighbor proteins around NZ_LT827010_12

CRISPR arrays

The CRISPR arrays of NZ_LT827010_12

>merge|NZ_LT827010|12|5588482-5588702|CRISPRCasFinder
GGGCGGCGGGAGGACGGTGCTCCGGTCCGGCGGGATGCCGGGCTTTCACCGCGGCGGGATGGTGCGGCCTCCGGGCGCCGCGATGAATCATCGGCCGGGCGGCGGGACGATGCGCTGCCGGGGCGACGGGAAAACTCGTTGCCCGGGCGGCGGGACGATGCACTGCCGGGGCGGCGGGACGATGCACTGCCGGGGCGGCGCGAGGACGCGCTGTCCGGGCG

>NZ_LT827010|12|10|5588482-5588702|CRISPRCasFinder
GGGCGGCGGGAGGACGGTGCTCCGGTCCG	GCGGGATGCCGGGCTTTCA
CCGCGGCGGGATGGTGCGGCCTCCGGGCG	CCGCGATGAATCATCGGCC
GGGCGGCGGGACGATGCGCTGCCGGGGCG	ACGGGAAAACTCGTTGCCC
GGGCGGCGGGACGATGCACTGCCGGGGCG	GCGGGACGATGCACTGCCG
GGGCGGCGCGAGGACGCGCTGTCCGGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_099344156.1|5602184_5603552_+|acyltransferase	unknown	unknown	gnl|CDD|376607
NZ_LT827010.1|WP_014692086.1|5594977_5596024_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635
NZ_LT827010.1|WP_014692094.1|5603688_5604222_+|chemotaxis-protein-CheW	unknown	unknown	gnl|CDD|366716
NZ_LT827010.1|WP_052311948.1|5600202_5600913_-|murein-L,D-transpeptidase	unknown	unknown	gnl|CDD|341130
NZ_LT827010.1|WP_052311719.1|5601101_5601866_-|hypothetical-protein	unknown	unknown	gnl|CDD|349398
NZ_LT827010.1|WP_014692080.1|5581828_5583250_+|DUF2252-domain-containing-protein	unknown	unknown	gnl|CDD|313268
NZ_LT827010.1|WP_172898908.1|5585637_5586798_-|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340842
NZ_LT827010.1|WP_085945650.1|5577697_5578771_-|sugar-binding-protein	unknown	unknown	gnl|CDD|380649
NZ_LT827010.1|WP_014692089.1|5598097_5598784_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_LT827010.1|WP_099343867.1|5598780_5600133_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl|CDD|273776
NZ_LT827010.1|WP_014692088.1|5596916_5598101_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|182528
NZ_LT827010.1|WP_043512133.1|5586997_5587240_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043512132.1|5580674_5581658_-|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|380488
NZ_LT827010.1|WP_014692078.1|5578851_5580339_-|L-arabinose-isomerase	unknown	unknown	gnl|CDD|179503
NZ_LT827010.1|WP_014692081.1|5583246_5583669_+|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase	unknown	unknown	gnl|CDD|274679
NZ_LT827010.1|WP_014692095.1|5604218_5605595_+|chemotaxis-protein-CheR	unknown	unknown	gnl|CDD|224271
NZ_LT827010.1|WP_014692087.1|5596064_5596913_-|EamA-family-transporter	unknown	unknown	gnl|CDD|227339
NZ_LT827010.1|WP_014692076.1|5576091_5577627_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|184134
NZ_LT827010.1|WP_014692075.1|5574847_5576095_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|226669
NZ_LT827010.1|WP_014692082.1|5583563_5585195_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	unknown	unknown	gnl|CDD|274589

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_099344156.1|5602184_5603552_+|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	2.84131e-19
NZ_LT827010.1|WP_172898908.1|5585637_5586798_-|glycosyltransferase-family-1-protein	gnl|CDD|340842	cd03814, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.	1.45878e-114
NZ_LT827010.1|WP_014692094.1|5603688_5604222_+|chemotaxis-protein-CheW	gnl|CDD|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	3.67537e-13
NZ_LT827010.1|WP_052311948.1|5600202_5600913_-|murein-L,D-transpeptidase	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	1.24983e-21
NZ_LT827010.1|WP_052311719.1|5601101_5601866_-|hypothetical-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	6.12189e-42
NZ_LT827010.1|WP_014692080.1|5581828_5583250_+|DUF2252-domain-containing-protein	gnl|CDD|313268	pfam10009, DUF2252, Uncharacterized protein conserved in bacteria (DUF2252). This domain, found in various hypothetical bacterial proteins, has no known function.	7.79292e-165
NZ_LT827010.1|WP_014692086.1|5594977_5596024_-|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	6.76468e-53
NZ_LT827010.1|WP_085945650.1|5577697_5578771_-|sugar-binding-protein	gnl|CDD|380649	cd19994, PBP1_ChvE, periplasmic sugar binding protein ChvE that interacts with a bacterial two-component signaling system. Periplasmic aldose-monosaccharides binding protein ChvE that belongs to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	2.13651e-147
NZ_LT827010.1|WP_014692089.1|5598097_5598784_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.99687e-109
NZ_LT827010.1|WP_099343867.1|5598780_5600133_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.65094e-31
NZ_LT827010.1|WP_014692088.1|5596916_5598101_-|ABC-transporter-permease	gnl|CDD|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	3.19183e-55
NZ_LT827010.1|WP_043512132.1|5580674_5581658_-|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|380488	cd01574, PBP1_LacI, ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of LacI is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	2.422e-110
NZ_LT827010.1|WP_014692078.1|5578851_5580339_-|L-arabinose-isomerase	gnl|CDD|179503	PRK02929, PRK02929, L-arabinose isomerase; Provisional.	0
NZ_LT827010.1|WP_014692081.1|5583246_5583669_+|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.35956e-22
NZ_LT827010.1|WP_014692095.1|5604218_5605595_+|chemotaxis-protein-CheR	gnl|CDD|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	4.41124e-54
NZ_LT827010.1|WP_014692082.1|5583563_5585195_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB	gnl|CDD|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	1.66659e-53
NZ_LT827010.1|WP_014692076.1|5576091_5577627_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|184134	PRK13549, PRK13549, xylose transporter ATP-binding subunit; Provisional.	0
NZ_LT827010.1|WP_014692075.1|5574847_5576095_-|ABC-transporter-permease	gnl|CDD|226669	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism].	2.17673e-121
NZ_LT827010.1|WP_014692087.1|5596064_5596913_-|EamA-family-transporter	gnl|CDD|227339	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism].	1.22752e-69

Protein sequences

>NZ_LT827010.1|WP_043512133.1|5586997_5587240_+|hypothetical-protein
MMPTPGTLRLVATLGAVPGLRPTVDSAIPPMVTWEDGPSGRAAAQALVASGYTVSEQFWGGGVVDVPTSNHAYSSASCGP
>NZ_LT827010.1|WP_172898908.1|5585637_5586798_-|glycosyltransferase-family-1-protein
MGGMRIALVTESFMPDVNGVAHSVVRTAEHLIRTGHEPIVIAPVPAPGPVPATLPYPVVRIPSVPMPGYPQIRLGLPMPALRAAIRDHRAEVVHLASPFVLGAWARTAASSLGLPTVAVYQTDVAAYARARNLGVCEDLSWRWIRRLHNAATRTLAPSTESMTALRTHGVERVHLWRRGVDDVRFHPGRRSAGVRRALCRDGEVLVGFVGRLAVEKEVDLLAGVSRLPHVRLVVIGDGPAEAHLRRALPEATFLGARHGGQLARIYASLDVFAHTGPFETFGQTVQEAMASGIPVVAPAKGGPRDLVHHDHTGLLVPAHEETGFTDAVARLAADPSLRRAMGAAGRAAIAGRSWSAVGDQLLHHYAEVLGRPLARQEVARPRAAAA
>NZ_LT827010.1|WP_014692082.1|5583563_5585195_-|polyprenol-phosphomannose-dependent-alpha-1,6-mannosyltransferase-MptB
MNNDRTGVRHRLLDACRSSRLGLLVARRRDHLPVLTTRALRWAGFGGALLLALAGLFGGALPDEGGHNLPVTTLWLAGTALLGYAWWSGRDRELSPRWVLGTAALWAVPFLLVPPVGSRDLYSYSCQGELFAHGLSPYTSTAQTLPCSWVGAVPPIWRDTITPYGPLFVLLAGAIILLGQAVALPSGLVDALPPHLGSLILPLVLFRLVALGGVVAMAAGLPVLARRCGIAPARALWLSLAGPLIGLHLLGGPHNDAAMLGLLVGGLAVVTRCPRHWAARVGGGVLLGAAVAVKATAGVAIPFAVLIVAATYRSRLQGLVIGTLAVAGSSVAALAGITVAGGLDLGWIAGLSDSGALVQFSSMPTAVGMTITYAGRLFDPDFDAVPAVRAAAYAVLAVALVVIWVRALRDRADPVRAALFGSAAAIVATVALAPVFLPWYMLWPLTLLAATTLRTKAVMVITIVASFSVLPDGSGLVRSLKFPGAPMVTLYLIYLGVRQVRRWRGGRELQALVAADGISEAEPSTRATATSMTTRAGLGRGVR
>NZ_LT827010.1|WP_014692081.1|5583246_5583669_+|TIGR03618-family-F420-dependent-PPOX-class-oxidoreductase
MSGVISLESTALREFWTERHLCTLTTLRADGSPHVVAVGATLDPETGIARIISSGGSAKVRHVLRGQQRVAICQVDGPRWSTLEGLAVIRDEPAAVAEAERRYAGRYRTPRPNPARVVIEVAVARVLGSASLMPSAATSA
>NZ_LT827010.1|WP_014692080.1|5581828_5583250_+|DUF2252-domain-containing-protein
MDATPTIGSPVVPGSAGDEGFTSLRRPARPRAERYEMGRALRERSPRSDVAQWRPPADRPDPVGQVRASHEGRLPWLVPVRIGRMIASPYAFLRGTAGLMADDFAGLPHTGITPVICGDAHLGNFGFYASPERDLVFDLNDFDEAHPGPWEWDLRRLVVSVHVAGRVNGFRESACAEAVQHCVEEYRGQIADLAARPLLARSFDRLNVDAMRSVATRGSFRDEIERAARRARRRTSDRALPRFTERRDGSRRLVEEPPVITRPSDADRDLLDEALDGYLNTLKPHWARILGGYRVIDVAHKVVGVGSVGLRAYVALCEGSDPEDVVFLQLKQARRSVIAKHQHGALAWHRHQGQRVVEYQQALQTVSDPLLGWTTVGEHQYYVRQFRDMKGAIVVEDINAGALADYAGICGYLLAKSHARTSGASMIAGYCGGSDKLDESLAKFARSYADQVEKDHQALVAAVRRGELAAEVA
>NZ_LT827010.1|WP_043512132.1|5580674_5581658_-|LacI-family-DNA-binding-transcriptional-regulator
MTDVARLAGVSHQTVSRVLNDHPNVKEQTRLRVRAAIAELGYRPNRAARALVTGRSQLIGVVARNSMLYGPASMLTEFEQAAADAGFAVSVGSVRELDRDSIAAVVDRHLDQRVAGLVVIAQVASATEALAEIPADVPVVCIDGDPAAGRSLVTVDQVAGARAAVRHLLEAGHETVWHVSGPTDWFDSAGRIQGWRQTLQEAGREVPPLLSADWSAAEGYRAGQMLARMPEVTAIFTANDHLALGVLRALHERGRRVPHDVSLIGFDDVPEAAYFIPPLTTVRQSFGDVARAALTLLLGQLRDAPRPADTVIVPARLVVRESVAPPA
>NZ_LT827010.1|WP_014692078.1|5578851_5580339_-|L-arabinose-isomerase
MKPQIWFLTGSQHLYGPETLQQVADQSAEIQRTLAAGLSAELVTRPVLTDSGAIKQVMLDANNDATVIGVIAWMHTFSPAKMWISGLDALRKPLLHLHTQHNISLPWESIDMDFMNLNQAAHGDREFGFIQARLGVPRKTVAGHVSDPSVVSRIDGWARAAAGLQRLRTLRLARFGDNMRDVAVTEGDKVEAELRFGVSVNTYGVNDLVTVVDAVDDKAVDDLVAEYADRYELAPELAVGGARHDSLRYGARLEAGLRQFLTEGGFGAFTTNFEDLGGLRQLPGLAVQRLMADGYGFGGEGDWKTSALLAAVKAMGTGTGRGTSFMEDYTYHFGPGEPKILGAHMLEVCPTIASARPRVEIHPLGIGGREDPVRMVFDATPGPGVVVGLADLGDRFRLVANAVEVVEPDEPLPNLPVARAVWKPAPSLSTSAECWLTAGGPHHTVLTQAVGAEVLRDFATMAQTELLLIDDRTSTDDFADRVRWNQAYHRLARPL
>NZ_LT827010.1|WP_085945650.1|5577697_5578771_-|sugar-binding-protein
MAACGSSEKTADKAAGSGNTAGALIGITMPTKSSERWIHDGDNLKQQLEGLGYKVDLQYAENDIPTQTQQLDSQITKGAKLLIIASIDGTAISNQLDNAKNAGIKVIAYDRLIRGNANVDYYTTFDNFKVGVQQATSLLTGLGVLKADGSKGDAKGPFNVELFAGSPDDNNATFFFNGAKSILDPFIKDGTIVVKSGQTDFKTVATLRWDPETAQKRMENILTSTYKSGAKVDGVLSPYDGISIGILSALKSGGYGTAAQKFPIVTGQDAEVASVKSIIKGEQYSTIYKDTRQLAKVTGEMADAILKGQTPQTNNTTDYDNGKKVVPAQLLQSVIVDKDNYQKVLVDGGYYTADQLK
>NZ_LT827010.1|WP_014692076.1|5576091_5577627_-|ATP-binding-cassette-domain-containing-protein
MTDTILRMTGITKTFPGVKALQDVDIEVRRGEIHAICGENGAGKSTLMKVLSGVYPHGTYEGDIEFEGEPCHFGGIRDSEHRGIVIIHQELALASNLSIAENIFLGNERSKRGWINWNETNAAADDLLRRVGLKEKAVTPVVELGVGKQQLVEIAKALSKDVKLLILDEPTAALNDDDSAHLLNLLRGLRDEGITCVIISHKLNEVMGISDRVTILRDGRTIWTDEIENLTEDKIISGMVGRDLEHRYPEHEPTVGEEVLRIEDWTVYSPTQPDRALVRKANLTLRRGEIVGLAGLMGAGRTELAMSVFGRSYGVNISGRLIKDGKEIKARTVREAIDHGIAYATEDRKRYGLNLIEDIKRNVSAAGLSKLAKGGWVDGNEEFKVADEYRASMNIKSPTVEAVVGKLSGGNQQKVVLSKWIFTDPDVLILDEPTRGIDVGAKYEIYTIINRLADEGKAILVISSELPELLGICDRIYTLSAGRITGEVPRAEATQESLMTLMTKEEQEVAP
>NZ_LT827010.1|WP_014692075.1|5574847_5576095_-|ABC-transporter-permease
MTVAPTNADLSISEGPAGAGNAAQRKVNFDLKSSGIYIALALLVLGFTIWTGGDLLAPQNLSNIIVQYSYILVLAIGMVLIIIAGHIDLSVGSVVAATGAFSAVMMVNWGLPWPVAVIATLVIGALIGAWQGYWVAYFGIPAFIVTLAGMLLFRAVTYMILGNKGIGPFPDEIRTLANGFIPGFLGNVGLGSLGGADLFSLVVGILVVVAMVFVQWRARMGRVRYRQAVDPMWLFVAKVAVPAALVIFLVVQLARFRNLPWVLVLLAILVCAYTLVTNRAVFGRQIYAVGGNLQAATLSGVKVKSVVFWLFVNMGVLSAVAGIIFAGRLNLAGPTAGNSFELDAIAAAFIGGAAVQGGVGKVVGAITGGLIMGVINNGMGLLGRAPEEVMLFKGFVLLLAVAFDVWSKRRTATAK
>NZ_LT827010.1|WP_014692086.1|5594977_5596024_-|GGDEF-domain-containing-protein
MPYQLRDQHGASRAVAYLMMVAGPYNLITGVLMKIGAPIAELISLGVTAVALMLVGVLCWRRPQVLPKLFWPAVPLLSTAVVTGLNYGTRDASTGAQLFFLWPLLFGACFLGRRITTLTVVMISAGHALIAFSYLPMSGALNDWIAMTVAMAMTAWVVTSLNDRNDRLRRVLQQQATTDSLTGVANRRALDEALHEAVRDADAGAEPAALIVIDVDHFKKINDTRGHAAGDQALRAVADALRAAGDGLVARVGGDEFAVLLRTGPTEAFRYAETARAALTAVPAAPTLSIGVAVVPHHSAASADELQRVADAALYQAKEAGRGRTVIASAPARQNVDRIPEARATSAF
>NZ_LT827010.1|WP_014692087.1|5596064_5596913_-|EamA-family-transporter
MHQRVPAPLLVLASIASVQFGSSVARKLFGDLGANGITFLRVGLAALIIAALTRPRVRDWPRRAWLAAALLGVVMAGMNLVFYQAIRTVPLGTAVTVEFLGPLLLALVQTRRLTDLLWALLAAAGVVLLGLHSGGAAPLAGLGLALLAGLFWAGYIVLSARVGALVPGTGGLAVSLSVGALLAAPFGLPGAGAVLYHPHLLIGATGVALLSSVIPYGLEINALRRIPTRIFGILMSLEPGAAAVAGLIVLGQRLGPIEVLALLLVTLASLGVTLAAPQPAPV
>NZ_LT827010.1|WP_014692088.1|5596916_5598101_-|ABC-transporter-permease
MRVAEAWRVALDALRANRLRSLLTMLGVIIGVAAVVALVAIGTGTKQQIEHQVEGLGSNLLIVVPGKLAVGSAPTSSPMTLADADAVSRVVGDRSRVAVTIASGETVRAGQRSGFASMQGVLETTPSVFVRHLARGAYLTRTDVSTGRRVAVLGAGVARTLFGDRDPIGRQMTVGGVRFRVIGVFEELGQSLGVDRDNEVHVPVTAAQRLLGTDRIDGLAIRAPDRDTIDRLGTDVVAALTERHPDTDFSAVTQEQILGVLGDILGVLTGVLAAIAGISLLVGGVGVSNIMLVSVRERTREIGLRKAVGARPRDIGVQFLLEAVLLTTTGGVAGMLLGAAAALLVDGLSPVPAALTWWSMALAFGVSAGVGIIFGVVPAQRAGRLDPVVALRTE
>NZ_LT827010.1|WP_014692089.1|5598097_5598784_-|ABC-transporter-ATP-binding-protein
MTTPAIVATDVTRTYELDGVSVPALRGVSLTVEPGDYVAIVGTSGSGKSTLMHLLGGLDRPTSGTLLIGGRNVGELTPNELAELRNTTIGFVFQSFHLLARTTAQDNVGLPLVYRGAGRRERRARAATMLQRVGLAHRITHRPNQLSGGEQQRVAIARALVTGPSLLLADEPTGNLDSATGQSILALLESLNAEGVAIVLVTHDRDVAARAGRQILMRDGLIVTDTAE
>NZ_LT827010.1|WP_099343867.1|5598780_5600133_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MCSVSRTPSRSALITGGTAVLLLLTAASCKDDNAGVHLGTATIGTVDEIVEAPGSVTARGAATLTAPAAGTVTDLRVQPGDRVKKGDVLAVIDSPELRQRRDAARRALAQTPSGGGGGVSAGNFTQVRRSTDRQAGQAFQDALTAADQITDPTLRDALRKQVSAAQQQYRAASAAAASAVRAVQRGVASLGQAVSSLSAAQRLQAQQAYELADAAVRALTLKAPVAGVVQFGGSASPAAPADLSALLQSGGATTGATTTAGGAEGVDTAVTEGSPVTAGAPLLTVVDVGRLGLTAQVDETDVLLVKPGVTADVELDAATGAAYTATVGSVDLLPTTSARGGVSYRVRLDLGDGTYTDGSGAAPTPRPGMSAVIRLRVRQVQQAVTVPASAVVSADGHDTVWAVRDGHYRAVPVRLGVQGEDTVQVQSGLPAGERIVISGADRVHDGAEAP
>NZ_LT827010.1|WP_052311948.1|5600202_5600913_-|murein-L,D-transpeptidase
MAAMVGGGLGAFAVTPASAGAAVRTTPVATSVVTRAAASSCATGRYQKQVETYLKQLGGYGTVTVDGRQSAADCAAIVRFQKRFGIQPAQGLAGPTTVDVAKRLASTKIAACKPNRKGITFCVDLTNQTTWVMKNGKLFVKPTITRTGMKGYHTPAGTFKINKRTPKEWSDPYHVWLPYWQRFIGGRGFHQTTTYLHDKWRGSHGCVNLLPQDAKQYYGIGTIGMTVKVFGRRPGT
>NZ_LT827010.1|WP_052311719.1|5601101_5601866_-|hypothetical-protein
MLSVATAALVAGGVATTRALAQEPPDVAGFTIFGGPVTSDASPAPDDAGPDPAAGLGTAPATIPARVITRKPAAEPTAEPTAEPAVEPGPIKAVAPKKNYGFAAAADPIAASHTEVTVESISSSPYAPVQQQILALVNLQRGRAGCRPVTIDRRLIDAANGHAAEMARRDYFDHASPNGKGAGDRVSANGYPWRLYGENIARGQRSPWEAMDAWMNSPEHRANILDCKLDQMGVGLAIDGGHTPYWVQDFASPQ
>NZ_LT827010.1|WP_099344156.1|5602184_5603552_+|acyltransferase
MRNRYLDLLRAAAIVRVIVYHLFGWSWLSIVMPAMGVMFALAGSLTAASLERRPARDVVTSRVRRLVPPLWLLGLLAVPVMIALGWSREHGGEHPFKVWKLAFWILPLGDPPGSELAVDAWEPLWYIRAYVWFILLSPVLWFLWKKLGPACWLLVIAPILAIVALDKTGFELPETADVVMWDFVTYAACWITGFAHRDGRLRRLAPATVVFLFVTLSCAGLYYQSGHQGDDPWDLNDVSESQSLYSLAFVLLALRWQPSMTWLSRTNLLDRAVTLLNARAVTVYLWHNLAIAAVWPVLSFLTADDLGHLEKPVTLGMTMTLTAVAVLLFGWAEDLAARRRPRLWPDTAIPAAADPAPTAPAPAPAPAAPAAVALDGTVPAGWPEVHRDGAPHAGWTDAGREGTPVAGRRPPAARHSTESAGASTEKRERPSRGRLSRKAKRQPESLIPTWWADKE
>NZ_LT827010.1|WP_014692094.1|5603688_5604222_+|chemotaxis-protein-CheW
MGQLRQAPAGEAGTIALVFQAGPLFCALPLAEVIETMRPLPTRPLAGTPSYVRGLTILRGEPAPVIDMTRLLTGVSSGIDRYVAVHAGRGPVACATGPVLGVRTVHAVPPEGPSTLFTGASRSLVAAVGTVGTEPLLVLRSIRTVPDEVWDAAGRDRDTAEPGTAQAVAAHDTGATG
>NZ_LT827010.1|WP_014692095.1|5604218_5605595_+|chemotaxis-protein-CheR
MSGEPPLVRFREILERRLGWAAADTEAVPVLPVLAERAAARQLTESAYLDRLAGRAWPEETVILAERLSITETYFFRHGDQFRALASRVLPQRIEARAGQRVLRMLSVGCSSGEEAYSLAIVAHRVRPAPDWIVAVLGVDANPEVLRRARRAVYSEWSLRETPPDVRSRWFRSVPDGYEVAREITGSVQFVEHNVAGPEDPRIWQPGRYDAVFCRNLLMYLTPATVRGVLDRITGSLADGGALFLGHTDSLGSAPPGFTVEHHGDTVFYRRSIAAPTPQPAPRAAPPRVAPPPRVRSPRTPEIRSRALDLLRDERFAEALDLLAPVSSQHPLLYGVLLAQLGRLPEAAAVATRLIDAGAPQPDAHQLLGLCREIDEPDQAAAQYRLAAYLDPGFAMPRLRLGLLARREGDETAAAAELTAALDLLPRESEERITLFGGGFGRLTLSVLCRAERDGARR

Crispr_ID: NZ_LT827010_13

• CRISPR_ID: NZ_LT827010_13
• CRISPR_location: 5886174-5886268
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_13

Consensus_repeat	Method
CCCGACCGGCGGAACCGTCGCCG	CRISPRCasFinder

spacers of NZ_LT827010_13

>13.1|5886197|49|NZ_LT827010|CRISPRCasFinder
AAGGCAGCCCCGTCTCGACCGGCGGAACCGTCGCCGAAGGCAGCCCCGG

CRISPR arrays and Neighbor proteins around NZ_LT827010_13

CRISPR arrays

The CRISPR arrays of NZ_LT827010_13

>merge|NZ_LT827010|13|5886174-5886268|CRISPRCasFinder
CCCGACCGGCGGAACCGTCGCCGAAGGCAGCCCCGTCTCGACCGGCGGAACCGTCGCCGAAGGCAGCCCCGGCCCGGCCGGCGGAACCGTCGCCG

>NZ_LT827010|13|11|5886174-5886268|CRISPRCasFinder
CCCGACCGGCGGAACCGTCGCCG	AAGGCAGCCCCGTCTCGACCGGCGGAACCGTCGCCGAAGGCAGCCCCGG
CCCGGCCGGCGGAACCGTCGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014692343.1|5884265_5885240_+|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_LT827010.1|WP_014692348.1|5888890_5889604_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
NZ_LT827010.1|WP_014692339.1|5879038_5880448_-|glucuronate-isomerase	unknown	unknown	gnl|CDD|235087
NZ_LT827010.1|WP_014692350.1|5890066_5890714_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_LT827010.1|WP_014692336.1|5876080_5876416_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380393
NZ_LT827010.1|WP_085945652.1|5892700_5893786_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379258
NZ_LT827010.1|WP_043512227.1|5880444_5881770_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_LT827010.1|WP_052311951.1|5874651_5875995_-|pectate-lyase	unknown	unknown	gnl|CDD|226384
NZ_LT827010.1|WP_014692342.1|5882982_5884260_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270303
NZ_LT827010.1|WP_014692338.1|5877587_5879042_-|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|223324
NZ_LT827010.1|WP_014692346.1|5886967_5887435_-|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224439
NZ_LT827010.1|WP_014692347.1|5887575_5888694_+|alanine-dehydrogenase	unknown	unknown	gnl|CDD|240630
NZ_LT827010.1|WP_014692354.1|5893973_5895080_+|ferredoxin-reductase	unknown	unknown	gnl|CDD|99812
NZ_LT827010.1|WP_014692337.1|5876393_5877491_-|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NZ_LT827010.1|WP_099344165.1|5886304_5886859_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014692351.1|5890701_5891955_-|two-component-sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_LT827010.1|WP_014692352.1|5891951_5892626_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043512229.1|5889871_5890054_-|hypothetical-protein	unknown	unknown	gnl|CDD|184582
NZ_LT827010.1|WP_014692344.1|5885240_5886074_+|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_LT827010.1|WP_014692341.1|5881947_5882973_+|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|224525

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014692343.1|5884265_5885240_+|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.04684e-79
NZ_LT827010.1|WP_014692348.1|5888890_5889604_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	3.6448e-06
NZ_LT827010.1|WP_014692339.1|5879038_5880448_-|glucuronate-isomerase	gnl|CDD|235087	PRK02925, PRK02925, glucuronate isomerase; Reviewed.	0
NZ_LT827010.1|WP_014692350.1|5890066_5890714_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.99174e-62
NZ_LT827010.1|WP_014692336.1|5876080_5876416_-|cupin-domain-containing-protein	gnl|CDD|380393	cd06988, cupin_DddK, Dimethylsulfoniopropionate lyase DddK and related proteins, cupin domain. This family includes mostly bacterial proteins homologous to dimethylsulfoniopropionate lyase DddK from marine bacterium Pelagibacter. DddK cleaves dimethylsulfoniopropionate (DMSP), the organic osmolyte and antioxidant produced in marine environments, and yields acrylate and the climate-active gas dimethyl sulfide (DMS). DddK contains a double-stranded beta-helical motif which utilizes various divalent metal ions as cofactors for catalytic activity; however, nickel, an abundant metal ion in marine environments, confers the highest DMSP lyase activity. Also included in this family is Plu4264, a Photorhabdus luminescens manganese-containing cupin shown to have similar metal binding site to TM1287 decarboxylase, but two very different substrate binding pockets. The Plu4264 binding pocket shows a cavity and substrate entry point more than twice as large as and more hydrophobic than TM1287, suggesting that Plu4264 accepts a substrate that is significantly larger than that of TM1287, a putative oxalate decarboxylase. Thus, the function of Plu4264 could be similar to that of TM1287 but with a larger, less charged substrate. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	1.48506e-12
NZ_LT827010.1|WP_085945652.1|5892700_5893786_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	3.49421e-14
NZ_LT827010.1|WP_043512227.1|5880444_5881770_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.81956e-34
NZ_LT827010.1|WP_052311951.1|5874651_5875995_-|pectate-lyase	gnl|CDD|226384	COG3866, PelB, Pectate lyase [Carbohydrate transport and metabolism].	4.18368e-54
NZ_LT827010.1|WP_014692342.1|5882982_5884260_+|extracellular-solute-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.57216e-42
NZ_LT827010.1|WP_014692346.1|5886967_5887435_-|Lrp/AsnC-family-transcriptional-regulator	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	7.35103e-35
NZ_LT827010.1|WP_014692351.1|5890701_5891955_-|two-component-sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.7074e-24
NZ_LT827010.1|WP_014692347.1|5887575_5888694_+|alanine-dehydrogenase	gnl|CDD|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_LT827010.1|WP_014692354.1|5893973_5895080_+|ferredoxin-reductase	gnl|CDD|99812	cd06216, FNR_iron_sulfur_binding_2, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap betweed the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	9.40298e-95
NZ_LT827010.1|WP_014692337.1|5876393_5877491_-|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.0402e-30
NZ_LT827010.1|WP_014692338.1|5877587_5879042_-|mannitol-dehydrogenase-family-protein	gnl|CDD|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	1.39448e-129
NZ_LT827010.1|WP_043512229.1|5889871_5890054_-|hypothetical-protein	gnl|CDD|184582	PRK14236, PRK14236, phosphate transporter ATP-binding protein; Provisional.	0.00691416
NZ_LT827010.1|WP_014692344.1|5885240_5886074_+|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	3.95844e-82
NZ_LT827010.1|WP_014692341.1|5881947_5882973_+|LacI-family-DNA-binding-transcriptional-regulator	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.20918e-95

Protein sequences

>NZ_LT827010.1|WP_014692344.1|5885240_5886074_+|carbohydrate-ABC-transporter-permease
MTARLTRPVLLIVLTALVLYPLLWMLGSSFKAPSEILNNFSVWPREWTPANYPDGWTHFDVAFGRFFLNSFLVAALTVLANCASCLLAAYAFARLRFRLRGFWFALMIGTLLLPSHVLIVPQFVMFRAFGWVGGPWPYLPLIVPHLLAADAFFVFLMVQFMRGVPRELDDAAKIDGCTPYSVFRHVILPLSRPALVSTAIFSFIWTWNDFFRQLVYLSDLSKYTAPVALTLFIDSTGQSAVGPMFAMSVLSLAPVFLFFVAFQRLLVEGINTTGLKG
>NZ_LT827010.1|WP_014692343.1|5884265_5885240_+|sugar-ABC-transporter-permease
MAVSTRPSRPRPQSGPAADQRRDRPARHRGEGRAGYLFLTPWLLGFAVITAIPMLMSLYLSFTNYDILSPFSEVTWVGWANYDRMFHHDPAYWHAVRVTLVFAFLATPLKLGAALGVALLLNRPFRGSGLFRGLFYLPSLLGGSVALAMVWHSLFDRGGSVNAVLGWFGIEGKAWVNDPHTALGTLILLAVWQFGAPMVIFLAGLKQVPAELYEAAEVDGAGTVRRFVSVTLPMLSPVIFFNLVLETIHGFQGFTSAFVLSNGTGGPVDSTLMYTLYLYIRGFANYEMGYASAMAWVFLLTIGLVTALLFRTGRFWVHYSDGDD
>NZ_LT827010.1|WP_014692342.1|5882982_5884260_+|extracellular-solute-binding-protein
MSALRLSRALMAAVLVLPLALAGCGGDDSSSAGKTQLTFFWWGGEGRAKLTQQALDLYTSRHPDITFKTTWQANQGYFDKLATLTAGDGAPDIFQIDDNYLAEYATRNVTLDLTSYKDSGKLDLSKFPESLWKYGVVDNKLAGMSMGENTQGLVYNKTRLEAAKQELPTTGMTWDQLIAWAQKAGAATKVPGTMDPSADYKAFWVWLRQNGKQFYNGNQLGFTSDDVQKWFELWKGARDAKATPTADVIHEGNATDITKQLVVTGKALTSWVWANQMPDIQKNTKDELGVVAYPGDPSAQWARASMYFSVYRGSKHRDAAVDVLNFLANDPEAGKILGTDRGLPSNLDIRRQVASSTTDPAMKASIALEDSLVSKFGPAPSVPPKGHATVKTELIKAAEAAQFGTASPAQAADQFFTAAQAAISR
>NZ_LT827010.1|WP_014692341.1|5881947_5882973_+|LacI-family-DNA-binding-transcriptional-regulator
MAVTIRDVAKASGVHISTVSRTFSAPHLVNPETRTRVLATAEELGYRPNRAARALITGRTHNIGLIVADIANPFFPPMIKAAETHARRRDYHVFVADTDEDPVVETDLVRALAKQVDGILLCSPRMSDDQIVESRREVPLVVVNRLIDGLPAVVMDVGAGARSAVRHLVDLGHRHLVYLAGPRGSWTNREIRKAAGAAARAGGADLTVLGPHAPVTTAGADAAEPVLATGATAVLAYNDLMAIGLLQSLQDRGIAVPERISVVGFDDIVTSALIRPTLTTVANPTAAAGRAAVDMLLQQGDDGATGQVTLRTDLVIRNSTGPGPYAPAGATRTEVAAYAKE
>NZ_LT827010.1|WP_043512227.1|5880444_5881770_-|Gfo/Idh/MocA-family-oxidoreductase
MQTFAEGDVVIRYALVGAGARAGMFIRALTGDHADVARLVALADTNPARPQVYRRRHDLDVPVYPATGFTEMLQRERVDVVLVTTVDRYHERYLVAAMEAGCDAITEKPMTVDAASCRRILETSRRTGRSVRVTFNYRYNPLHEAVKRALPEIGEIGSVHFEWLLDVRHGADYFRRWHREKQNSGGLLVHKAGHHFDLVNWWLDDAPEQVFAAGRLFFYGEAGRRHGYARDYDRAHGAAAAEGDPFALRMADEPAMRELYLDAERHDGYLRDRNVFAPGVTIEDDMAVLVRYAGGASMSYHLTAYAPWEGYRVMVNGSRGRLELEVVETDHVAPAAAAGVKGEPGAVSTAERGWRRLLLRPFWAPPREITVDGYSRQGHGGADLRMLADLIRPDAPPDPLGRGATAVDGARALLTGLAANESLATGQAVRVSDLLDLEEIR
>NZ_LT827010.1|WP_014692339.1|5879038_5880448_-|glucuronate-isomerase
MTLFPAEATQRGIARELYAHARDLPLISPHGHVDPALLAEDEPFGDPARLFVVPDHYVTRMLASQGIPPARLGVPSIDGSPVETDGRAVWRLLAENWHLFRGTPSRLWTEKVFAEVFGIGKRFSAATADEIYDQLSARLAEPDYRPRALFTRFNIEVLATTESPIDDLGVHAKLAADGWGGPGGRVITTFRPDNLVDMEWDGWADRVAALGALTGQDVGTYPGFLTALRARRELFVAAGATCSDHGHPTAATLDLDDAEAAVLYRKGLGGAADARDAEAFRAHMLVEFARMSIDDGLVMQLHPGSVRNHNQALYARHGRDVGGDIPSATEYVRALRPLLDRYGHDPRLRIVLYTLDETAFTRELAPLAGGYAALYLGAPWWFLDSPEGLRRFREAVTETAGFYNTAGFVDDTRAFCSIPARHDVARRVDAGFLARLVAEGRLPLDEAAETIADLAYHLPKRVYRLDRAA
>NZ_LT827010.1|WP_014692338.1|5877587_5879042_-|mannitol-dehydrogenase-family-protein
MTVTTTLGRAALPGLAPQARPLVTPGEVRPGILHLGLGAFHRAHQAIYTEAAVAAAGGDWGIVGVAPRSRDVLDKLRAQDRLYSVLTVGGDGGDRARAVGILSGLGHAAGDPYGVLAAIADPGIRIVSMTVTEKAYRLGPDGKLLLDDDLRAQLTGQAPPVSVPALLARALLSRSAPLTVLCCDNLQGNGPRIRGMVEQALEVAGAGLPDGVDFPATMVDRIVPATSAGHLRRAAVALGAADAAPVVAEPFHQWVIEDRFPGGRPDWAAAGAIMTGNVAPWETLKLRALNSVHSACAYLGALAGQEMISDALALPGMGGLLRRFLAEDIAPTFTPPPGIRVADYGETVLDRFANRELGHRTHQVAMDGTQKLPHRLLGTLADRRRAGAVPVWGALVLAGWMRFARGYADDGTALPLDDPLAGRIRAVVSAAPDTPAGLVDALLGVTEVFPAALAFDTALRAELIRWSGELARHGAAATIAAAGR
>NZ_LT827010.1|WP_014692337.1|5876393_5877491_-|Gfo/Idh/MocA-family-oxidoreductase
MTARVALIGAGGHGLSHRRKLRELAGLGELEIAALCDRNPVDPEPAVPVFTDHGAMLAAVRPDAVIICTPPHTHLPIALDCLAAGVDLLLEKPPVTSLREHETLVTAVRESGRRCQVGFQALGSAALTRFRELTAASAGDLSAAGAWWRPDTYYRRAPWAGRQAAFDGALVNPFAHALMQALAVADGFEPVLLELERYRTRDIQTDDCTFLRLTDGDGRRIVAAVTLASPVFVAGEIRLGDIVLEYPTDRVLLGRTHHELWGRTGLLENLLSGEPLVAPLERTRAFTAVAEAIVAAPLPATVPAGELRPHPDGDGNVLPGADELVRQVAATGLLPSETDVSWAAPPHRVTLETRKGTTDAQTERR
>NZ_LT827010.1|WP_014692336.1|5876080_5876416_-|cupin-domain-containing-protein
MRKLSVAELEAHHRGATFTSVLPGHVVQKGGFRVYAEPNFRTHDEPGRHVHTVPEIFVIVQGSGVMEVDGAEAGEFRAGDAVIFEPGEDHHLISRGPDPLVFVWMHLEPVS
>NZ_LT827010.1|WP_052311951.1|5874651_5875995_-|pectate-lyase
MSRRSALAATIGLVLAGVATVPAAASASAATIPGSAVPGSAVPGVAVPAAARQVLPVNDGWANGATGGSAAAADHVHVVRTRDELAAALAPADTAPRIVLITGTLRPDGDCAAYTDPAYSLDGYLGAYDPAVWGRTSKPSGPLEEARARSAKNQAADVQLKVPSNTTILGLANARLVGLNLLISAADNVIVRNLRLEDAADCFPQWDPTDGATGNWNSAYDLITLVGGTHVWADHNTFSDGDDVDANQPLYFGRPYQVHDGALDVIKASDLVTISYNVFQEHDKTMLIGSTNTVGADVGKLRVTLHHNRFANIGQRAPRVRFGQVDVYDNYYYATDEDFYQYSWGAGVYSAIYAENNFLLRSADIPLDAVVHNWGGTAMTEKGTLTRIGTGKVTPVSLLAEYNATHDPDLGTDAGWTPTLRPGPLTPTAQVPAVVTAQSGAGRINLS
>NZ_LT827010.1|WP_099344165.1|5886304_5886859_+|hypothetical-protein
MVRGDWRERLALATDLAMIGVVATVLALPLITAPAALAAGSVAVRARYRDGRIPPWRSLTAAYRRGVLPGMTALPAVALLALDLAAVRGGRVPGGTPLFAVTTVAAIWLTGVGTLTLAMLGRALPWREAARQAWNRPWCASALAVINLVAVFLALTVPATIPLVIGFHLFAAHMLADRLAPPLV
>NZ_LT827010.1|WP_014692346.1|5886967_5887435_-|Lrp/AsnC-family-transcriptional-regulator
MTDLPKDVRGLDHIDLELLSLLRADGRMPNNALAERVGIAPSTCLTRIRRLREIGAIRGFHADVDPSWIGRPIQAMIAVRIRSDARDGIGKFAESLAGIPAVRDVYFISGNYDFLLHVAAADVDDLRSVITERLSGTRLIAGTETYLIFEHRRGG
>NZ_LT827010.1|WP_014692347.1|5887575_5888694_+|alanine-dehydrogenase
MHIGVPKEVKNHEYRVAITPAGVVEAVRHGHEVVVQAGAGVGSAISDDDYVAAGARILPDADAVWGAADMILKVKEPIAEEYHRLRAGQVLFTYLHLAADPQGTKALLHSGTTAIAYETVQLADGSLPLLAPMSEVAGRLAPQVGAYSLMRNSGGRGVLPGGVPGVAPAKITVIGGGVSGANAATIALGLGAEVTVLDLSIPRLRQLDAQFGGRVRTLVSSTYAIEQSVLEADMVIGAVLVPGAKAPTLVGNDLVKRMKAGSVLVDIAIDQGGCFEDSRPTTHQDPVYQVHNSVFYCVANMPGAVPNTSTYALTNATLPYVLRLADLGWKDALRADPALALGLNAHDGVLTNDLVGKALGLDTESVSSVLAA
>NZ_LT827010.1|WP_014692348.1|5888890_5889604_-|hypothetical-protein
MRTKIVLFAGAAAVALLAGGCGDKATPAAAPGAGAVASAASGVAAAPGGASAAPADAANSAPGVTPTKNTPVSTSQPKPGTTKDGQPGPAPAGDPGDGGNWFAALTPCPNKGQQHEVQKLVFADVTGDGVKDALVASTCQTTNAYWPSTVEVFDGTTGKKPKRLGVLLKDVGPTDEPWYVSSSVSGKVVTVKAYGLSAQAPRACPDLNLTYTYKYGNGTFTRTGRQAAKASGCLPIQ
>NZ_LT827010.1|WP_043512229.1|5889871_5890054_-|hypothetical-protein
MDDEPMTAEEAELSRIERFGQLPPRVRAEDLVEMADTRSGFETPVTTMTEDERTLRYGAG
>NZ_LT827010.1|WP_014692350.1|5890066_5890714_-|response-regulator-transcription-factor
MADVIRVLIADDDRLVRMGLSLVLGADRQLEIVGEAADGVEAVEMTRRLRPDVVLMDIRMPRMDGLAATAEIRRYGPEPVVIVLTTFDTDDYLLGALREGANGFLLKGVAPEEILDGVRRAMAGESILAPSVVPRLIRHAVGGSGRPRRDRRLQRLSGRELEVAEAVATGRSNAEIGAELNMSVPTVKAYVSRLLEKLGCANRVQVAILVHESRR
>NZ_LT827010.1|WP_014692351.1|5890701_5891955_-|two-component-sensor-histidine-kinase
MTRRQRLAAASGERVFDAIAIVVSAVGAVAIAAEAEAAGRIGGDATFYSLLLAVVASGALWWRRRHPVAVAALFVPVTVATDFAGVAAVIALYTLITRRRGWVIPLLFGLHLLAGTGYSLLRPDPHLPAAAEFAVTLAFLTATAAVAVAMRARRDLVDVLRERALRAEEEARMRAERLRALERERIAREMHDTLAHRISMVSLHAGALVIRPDLTAEEIARSAATIRESAHAALEDLREILGLLRAGPDDLRPQPDLAQVGELVAEARAAGVPARLDNGLAGGVAGSALGRTVYRVVQEGLTNAAKHAPGMPVHVTLGRTGDGMVHVTVTNPLDRPAGVHPVSRASGVHPVTRPAGVHPVSLPAPDEGREPPPGAGAGLIGLGERVDLLGGRFEHGVRREGDERLSFRMEAWLPWRM
>NZ_LT827010.1|WP_014692352.1|5891951_5892626_-|hypothetical-protein
MTRTSATLDYSPTDRVLIAAGPAVLGLLLAGVLPIGARWALGLHLPLPLRPAVTVVARVDAPWEFAVQAVLLAGAGLIASAALHERLIPISVSPDRLRLGGTELARAGIAAIYPDRDTLIVLDHESRPAARGIPRARRGTLAATLREFGYPWRDTDPYADVYRPWTAGADGLPPAVEAVLAARAVALERKAGRETAALRDSLARLGHVVRDEGGRQFWRPLVRS
>NZ_LT827010.1|WP_085945652.1|5892700_5893786_-|helix-turn-helix-domain-containing-protein
MEVPAYAEAFAGELGHKIERAVQAALGTFLNLVSRPGTDPGTPLAAALEAAYALGRGEARSGRSLDALLSAYRVGARVAWRELAAISVRSGQPAGTIADFAELVFAYIDELSAASVAGHADELAASGRIRLRHLQLLAQALVAGEPSHVLQAAAERAEWTPPQTLTAVLLPERSSRSLIDLLDPRTLPLAGALPDLPGTAVLLVPDPQGASRPHLIRLLTGHNAVLGPARPWQRAQCSVERAVRVHQLHTPIGGAVVDTEEHLAELVVSADRGALADLRDRALAPLAGERGAAAAKLVETLRSWLLHHGRREDVATELFVHPQTVRYRMARLRELYGEKLKDPQWVLALTIALAVPPVAEA
>NZ_LT827010.1|WP_014692354.1|5893973_5895080_+|ferredoxin-reductase
MLSPVRAARLGQVAVTQTLRNGAWRVVELITTPVVPTDYLDVIAPLRNPNVLRGRIEAVRRETPNAVTLDLRPGRGWRPHEPGQYVRLGVDVDGIRLWRAYSVSSAAGHPSGRISVTINGVRDGVVSAYLMKNARRGMIVNLDLPAGDFVVPRQRPAKSLFVTAGSGITPVMGILRSLVHELSDAVVVHSARTGPDVVFGAELRALAAAGSITLIERHTATDGRIKPADLDALVPDLFERETWACGPGEMLDAMADHWAEAGAGERLHVERFRPTVLVAGDGGTVTFERSGAVVEAPAGVSILDAGEASGQLMPSGCRMGICYSCVLPMREGIVRDMRDGQITTAVEGDNVLIQTCISAAAGPCHLDA

Crispr_ID: NZ_LT827010_14

• CRISPR_ID: NZ_LT827010_14
• CRISPR_location: 6195834-6195947
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_14

Consensus_repeat	Method
GGGGCCCGCAGAGGAATCCGGACGCGCC	CRISPRCasFinder

spacers of NZ_LT827010_14

>14.1|6195862|58|NZ_LT827010|CRISPRCasFinder
GGGACCGCTTCGTCGCGGCCGAGGCCCGCGGCGTGCCGGGGATGACCCCGGCCCGAAG

CRISPR arrays and Neighbor proteins around NZ_LT827010_14

CRISPR arrays

The CRISPR arrays of NZ_LT827010_14

>merge|NZ_LT827010|14|6195834-6195947|CRISPRCasFinder
GGGGCCCGCAGAGGAATCCGGACGCGCCGGGACCGCTTCGTCGCGGCCGAGGCCCGCGGCGTGCCGGGGATGACCCCGGCCCGAAGGGGCCCGGCAGAGGAATCCGGACGCGCC

>NZ_LT827010|14|12|6195834-6195947|CRISPRCasFinder
GGGGCCCGCAGAGGAATCCGGACGCGCC	GGGACCGCTTCGTCGCGGCCGAGGCCCGCGGCGTGCCGGGGATGACCCCGGCCCGAAG
GGGCCCGGCAGAGGAATCCGGACGCGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014692620.1|6196064_6197633_-|DHA2-family-efflux-MFS-transporter-permease-subunit	unknown	unknown	gnl|CDD|129794
NZ_LT827010.1|WP_014692626.1|6203850_6204270_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_155123638.1|6185398_6185671_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014692629.1|6206603_6207518_-|sugar-ABC-transporter-permease	unknown	unknown	gnl|CDD|224096
NZ_LT827010.1|WP_014692618.1|6193839_6194403_-|VanZ-family-protein	unknown	unknown	gnl|CDD|377417
NZ_LT827010.1|WP_155123639.1|6185669_6185966_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014692616.1|6190465_6192418_-|polysaccharide-biosynthesis-protein	unknown	unknown	gnl|CDD|224011
NZ_LT827010.1|WP_014692619.1|6194695_6195301_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_LT827010.1|WP_014692624.1|6202048_6203260_+|sensor-histidine-kinase	unknown	unknown	gnl|CDD|226951
NZ_LT827010.1|WP_043512311.1|6203178_6203844_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|225107
NZ_LT827010.1|WP_014692617.1|6192785_6193907_+|glycosyltransferase	unknown	unknown	gnl|CDD|340836
NZ_LT827010.1|WP_014692628.1|6205700_6206597_-|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl|CDD|223472
NZ_LT827010.1|WP_014692623.1|6200842_6201847_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014692622.1|6198729_6200646_+|elongation-factor-G	unknown	unknown	gnl|CDD|237358
NZ_LT827010.1|WP_014692613.1|6187417_6188518_-|hypothetical-protein	unknown	unknown	gnl|CDD|99740
NZ_LT827010.1|WP_014692621.1|6197769_6198381_-|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NZ_LT827010.1|WP_014692627.1|6204336_6205704_-|beta-glucosidase	unknown	unknown	gnl|CDD|274539
NZ_LT827010.1|WP_043515552.1|6188507_6189149_-|sugar-transferase	unknown	unknown	gnl|CDD|376775
NZ_LT827010.1|WP_014692615.1|6189179_6190436_-|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|223749
NZ_LT827010.1|WP_014692612.1|6186156_6187380_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014692620.1|6196064_6197633_-|DHA2-family-efflux-MFS-transporter-permease-subunit	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.36921e-128
NZ_LT827010.1|WP_014692622.1|6198729_6200646_+|elongation-factor-G	gnl|CDD|237358	PRK13351, PRK13351, elongation factor G-like protein.	0
NZ_LT827010.1|WP_014692629.1|6206603_6207518_-|sugar-ABC-transporter-permease	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.93978e-81
NZ_LT827010.1|WP_014692618.1|6193839_6194403_-|VanZ-family-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	8.7816e-10
NZ_LT827010.1|WP_014692616.1|6190465_6192418_-|polysaccharide-biosynthesis-protein	gnl|CDD|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	7.46128e-176
NZ_LT827010.1|WP_014692619.1|6194695_6195301_-|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.51469e-26
NZ_LT827010.1|WP_043512311.1|6203178_6203844_+|response-regulator-transcription-factor	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.61038e-72
NZ_LT827010.1|WP_014692627.1|6204336_6205704_-|beta-glucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
NZ_LT827010.1|WP_014692617.1|6192785_6193907_+|glycosyltransferase	gnl|CDD|340836	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.	8.92822e-59
NZ_LT827010.1|WP_014692628.1|6205700_6206597_-|carbohydrate-ABC-transporter-permease	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	7.1606e-79
NZ_LT827010.1|WP_014692624.1|6202048_6203260_+|sensor-histidine-kinase	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	5.71425e-40
NZ_LT827010.1|WP_014692613.1|6187417_6188518_-|hypothetical-protein	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	0.00114944
NZ_LT827010.1|WP_014692621.1|6197769_6198381_-|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	2.05e-12
NZ_LT827010.1|WP_043515552.1|6188507_6189149_-|sugar-transferase	gnl|CDD|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	1.37687e-83
NZ_LT827010.1|WP_014692615.1|6189179_6190436_-|nucleotide-sugar-dehydrogenase	gnl|CDD|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	2.8987e-166

Protein sequences

>NZ_LT827010.1|WP_014692619.1|6194695_6195301_-|response-regulator-transcription-factor
MIRVVVVRDEGYFGVPVRTFLEPEPDMHYVTTLPINGELAARAAQLWPAVIVIDTEYMVSQVLPIADALHTAIPSCAMLLLCDPSKRGMLPPRRWNGGMNFLTKSAAGAALADSVRRLAAGERVVSPMLQAASLNTDRGLSTRELEVLGLAAEGESVKEIAGRLYLSGGTVRNYLSAVISKTGARNRLDAIRIARKEGWLR
>NZ_LT827010.1|WP_014692618.1|6193839_6194403_-|VanZ-family-protein
MLVDRLEIPALPVLLPLGAVLMVLSWWWLRRQGRLTTRRLVVAWALCWYAVAVLGATMLPAHLSWGPGAGPPATYRILLVPTLSMRRRDFVLNMMMTLPLAALLHLNFGIVDRLWVVRTGFLLSLSIETTQLVMILTVHGTRWADVNDLLSNTIGTIVGFVVWHRLMRVERLRAAVTGVAPQTVRPG
>NZ_LT827010.1|WP_014692617.1|6192785_6193907_+|glycosyltransferase
MRVLHVISTASEGSAAHQLRLLLPRLPHDSEVVSLGPGGLISGVPVHQLGTARDRDPAAIVRLRALIRRGHYDLVHTHLYRACVQGRIAARLAGVPHIVATEHHLGRPGATRLGPFYLLSERLGEMTIAATASIAGRLRGWGVPDRRITVVPRAIDPGEYRFDPALRAAARRRLGVPGGTAVIGVTGRLHPAKRHDLLIRALTEVPGAVLLLAGDGPARPALHQLAIIEGVADRVIFAGAVRHPREMLCAMDIYASTDPHTWGLSVLEAIAAGLPAVYAACPPLEERRAARAPVRGTYRLSPHDRESLPRALRAEVLCLAERRGTRMPARTAGLRYDADHLAATVGQIYDRLTRAAPSAGPLRSLRHGDAPPA
>NZ_LT827010.1|WP_014692616.1|6190465_6192418_-|polysaccharide-biosynthesis-protein
MQTRRAAAGDPAADPAPAAWPGRAAPWFRAALPGQAARAGADALALATALLIATLLRHDGHPEYLNGAGLMELSLVAAVVHTVAGLWTGLYTGRWSYGCFEEILALAKTAAITTPAVFVLDTLLGRLVPRSAIIGAGLTGLVLAAGVRYAVRLLHDQRLRPHQAGTRVVVMGAGEGATQVIRAMLRSPSSPYVPVALLDDDPAKRTRQIMGVPVAGNRHAMAEVVRNLRADTVVIAIPSAGAELIRSLTDLAAPLDVDVKVVPRVVELFGRTVRVEDIRPVSHADLLGRREISIDLAAVAGYLQGRRVLVTGAGGSIGSELCRQVAQFNPATLVMLDRDESGLHAVQLSLDGKGMLDDRNLVVADIRDQQRLDEVFAEHKPHVVFHAAALKHLPLLEMHPSEALKTNILGTYQILQTAIRHNVDRLVNISTDKAADPCSVLGYSKRITERLTAAADAAAPGTYTSVRFGNVLGSRGSVLTAFAAQVEAGGPITVTDPEVNRYFMTVQEAVKLVVQAGAVASRGEVLVLDMGEPVRIADVAKRIAESAGGHIRIVYTGLRPGEKLAEVLLGPDEPDHRPNHPLISQAPVPPLDGAVLSLLDPRSPREDLIAVLRWLAESPALPGRVEKPPAPRSGGSRRHAEFTMRLGRHP
>NZ_LT827010.1|WP_014692615.1|6189179_6190436_-|nucleotide-sugar-dehydrogenase
MRVVIAGQGYVGLPLAVRAAEAGHHVVGYDVDEDRIKRLAAGESYVDDITSGQLQQVLSGGNFHPSADPRTCAGFDVAVIAVPTPLRDGTPDLRHIEESARTLARYLRPGATVALESTTYPGTTTELVGPLLEEGSGLIAGEDFHLGYSPERIDPGNRQWHLATTPKVVSGINPESLARVQAFYASVVETTVPVSDPKVAELAKLLENTFRHVNIALVNELAVYAHDLGIDVWEAIDAASSKPFGYMRFVPGPGVGGHCLPIDPSYLSWRVQRTLGQSFRFVELANDINNHMPDYVVRRLVVAMNRRRRAVNGSTVLLLGLAYKKNSGDARESPARRVAALLLEMGAEVLAADPHVVEDAHVDQRVTRVRATREVIAAADAVVLLADHDAFDLDEVVEHATYVLDTRHRITGTNVESI
>NZ_LT827010.1|WP_043515552.1|6188507_6189149_-|sugar-transferase
MWNVLNQLVALVALLLLSPLILAVALWVRIADGKGVLFVQARAGKDGRPFRMLKFRSMVHNSVAMSAQLGMADPFGLLQDDPRITRCGRILRRTSLDELPQLINVLTGRMNLVGPRPDVLPQVANYSAEDARRLEVRPGITGWAQVNGRDDIDWPARFVLDRWYIDHWTPLLDLKILARTVTGLRRAEPPVHVDTLNIARSAVDATQELGRAA
>NZ_LT827010.1|WP_014692613.1|6187417_6188518_-|hypothetical-protein
MPPDREIGSEFHWDPLALVGEDRGGLPGWVPARRELFATGCGAIRAVLRVLAPAGRLHVPSYFCTGVAEALTECLPVTFYRHLPDGHGPHWETLRVRGGDVVLAQNLFGWDDKAPWDAWIRAHPGIAVVEDHSHDPFSGWARNSIAAYVVASLRKTLPLPDGGLVWSPAGRPLPAPAGAESPGAAQKLAAMLLKAGWLDGQPVPKEAFRALQRQGEGALLGSDGPASTVTRAVLPLLDVLGIRAASSRNAHALRTALHGRSADEILGFARGAADVAPFRVQLALRSEKDRDTLLALLAAERIYAPVHWRQDRARWWSGDPEAAGLADRMLTLPVDHRCSSDDVSRMAEVVTSQASRESRSGHIIRA
>NZ_LT827010.1|WP_014692612.1|6186156_6187380_-|hypothetical-protein
MTAGGWIALGIAVFGSLCYAAGSILQAVGARRSTSAVTTLGHPLYLVGIGLDMTAWLGSMVALRQLAVYLVESVLAGSLALTAFAAWAFLGSPLRKRDVAAIGVTIGALAGLAMSAGQQHVVAASFTLRLSFIGALIVVLGLGFAATRIGSPGLIATIGGLSVGAAALGGRALHLPDEQMRTVGSAAMAILGEPLTYVLLLFAANGMVMYANALQSGEVGRVTAIHWTAEVIAPSVIALTLLGDTFRPGWWPVALAAAVITVGCAVVLASAPATATLDETAALPAGAEPHALPAPPLPVLPGAPGHPVTALVPLQAWRLAIPIEARWPALQPPLVRGYGTVVWWGPSWAPLPIWVPPDRTLVPRDRPKLADRPQRIWPARVGPQLPESRRPARHREIIIPGRDRDAA
>NZ_LT827010.1|WP_155123639.1|6185669_6185966_+|hypothetical-protein
MYLTPAGEVVIDHEEDSQARLAEPAERDFALARAAEQYPELAYLKPAKPLDAVMCNLCTGRGWLSVVQGTLPSSQNADQSKPFFYCPECASLGWTMAG
>NZ_LT827010.1|WP_155123638.1|6185398_6185671_-|hypothetical-protein
MTDPQRLKTGRRPESVQSLRQSDAWVASSINRSINRAFVMGSASSVIGWDGQVDRSPVPITVSTPWYGVEGWIGWFRRNQRVAVSSLNQR
>NZ_LT827010.1|WP_014692620.1|6196064_6197633_-|DHA2-family-efflux-MFS-transporter-permease-subunit
MTSRTEAAPAKLDAAVLKIAGVVVLGAIMSILDVTVVSVALPTFQREFNATYAQVAWTMTGYTLALATVIPLTGWAADRFGTKRLYMTALLLFTLGSVLCSTADGIGQLVAYRVLQGLGGGMLMPLGMTILTRAAGPERIGRLMAVLGIPMLLGPIGGPILGGWLIEAANWHWIFLINLPIGAIALVYSWFALAKDSPEPSESFDFLGMLMLSPGLAAFLYGVSSLPGEGSFTATRVWAPMLVGGLLVIAFVIYSFKPKHPLLDLRLLRNRNLSVATITLAVFTIAFMGAGLLFPSYFLQVRGESTLHAGLLMAPQGIGAMVTMPIAGMLADKIPVGRTVPFALLLIAAGFFTFTQVGTDTSYVLLCGSLFVMGLGMGGTMMPIMTSALKTLTSHEVARGSTLLNILQQIAGSVGTAMMSVILTNQLNDSAVVPGMTAPDGSPVTEAGVAIASWSDPKIAQAVPADLLHRGLAFVADSFATTFWVGFALTLSTLIPAFFLPRKRQESQLAADGAPAAPVIVH
>NZ_LT827010.1|WP_014692621.1|6197769_6198381_-|CPBP-family-intramembrane-metalloprotease
MTVVAVVGIIGLVRLWTRFGPGWAQPVTGPLAAALLITVSGRTARQAGLTVSGWRYAAAAVVLIGVGYAVAVRLPAARRLFRTTYDRPWLTALIEVPLATVVFEEVAFRGVLWSLLDRDHGAVAATAVTAVLFGLWHLAPERPWTDAVVTGVAGVLLGVLRAVGGGLLAPALVHWAVDGIGVLAAAHVTRTGVQWGRPQAGAG
>NZ_LT827010.1|WP_014692622.1|6198729_6200646_+|elongation-factor-G
MRVRNLGILAHVDAGKTTLTERILFTTGATHKRGEVHDGTTVTDFDPQERDRGITIFAAAVSCDWAGHRLNLIDTPGHADFSDEVERALRVLDGAIAVFDGVAGVEPQSEAVWRTADRYRVPRIAFVNKLDRAGASLTAVAESMRVRLGVVPLLVQFPLGAEGAFRGVVDLVGRRTLTWADGVLSVHDGMPPEALPARRELEEQVAGLHPAALQEWGDMSDATLRDALRDLTRSGEAVVVLCGSAYRNRGIEPLLDAVTDYLPAPAVPAGADPVALVFKVHTARAGRLTYLRVYQGTIVKGDTVWDAGAGRTERIARILRVQADRHTEIDRAAAGDIVAVTGVKHAPVGATLSSRAHPVRLEAPRITEPLVSVAVEARTRADAERLPPALAALAEEDPSLSVRVHPETAQTILSGLGELHLEVALEKLRQRTGLRVTVGRPQVAYRETVRRGVRDLLYRHVKQDGGAGQFAHVVLTVAPAGDTGFAFESAVTGGRVPAEYIRAVEAGCREALGDGPLGGHPVTGLRVTLTDGRTHPKDSSELAFRTAGKLALREALRACVMELLEPVAEVTVTAPADTLGAVLSDLAARRAQVTDSGERTVTATVPLAGLSGYATRLLSCTHGRGTFTSRPAGYRPAA
>NZ_LT827010.1|WP_014692623.1|6200842_6201847_-|hypothetical-protein
MRRLSPVFALFFLSPLVGEFFLGDFAITLLPLIFVFAPMYGGAAVLIREVTRRTGRGWPTIVTLALAYGVLEEGLITQSLFNKDYLDQHLLDPGYIPAIGTALPWVVFVLTLHTVWSISVPISLVEESSTRRTRPWLGRIGLTVITVLMLGGGFAVFNATRTDPSLSHGFLESSPQALSIVGIAVVLIVVAFLLPRPAATEPAARPVPGTAPGPWVVLATGILAGLLFMSVTWSIVPTVPGVVLMLVATLGTAVVVSRWARRAGWGPWHRFAITAAALLTYTWHTFFAHSAGFVLDLISHLVYAAAALAILWYVARRIRAKAPLGETDRLHAVG
>NZ_LT827010.1|WP_014692624.1|6202048_6203260_+|sensor-histidine-kinase
MTQTPHRAGPEWTWALNAGRAITLVVLAGATVALAAPEHRVLAAIALAVSFCGSAYGLRQGPERWIQRLLGLALFAVGGVALLAADGRAPGWLACGVAIIAGVARLPLRPGLVFAGAVVAATCLAPLARGAGRDVPLMAAICAAALVVALVISGARNRAVTAEQLLEAEQAARESAAERDRLAERQRIARELHDILAHTLSAQTVQLEGARLLLDRGALEPARERILVAQRMARDGLEQTRRAVQSLRGDARPLVEVLRALAADADARYAESGEPWPLTPPEALTVERTVQEGLTNARKHAPGATVTVLVAYTPDELRVEVKDTGWHGNAAEAVAPADIPPGGGYGLTGMHERAALIGADLLTGPDDSGPDGKGYRICLTLPRSGPSASSSPTTSAWSATVSS
>NZ_LT827010.1|WP_043512311.1|6203178_6203844_+|response-regulator-transcription-factor
MSDAAQERPIRVVIADDQRMVRDGVQLMLELIDGVEVVALATDGNEAIAAVAAHDPDVVLMDLRMPHCDGTTATRRIRAEHPRTQVIVLTTFADDSDVLAALRAGARGYLTKDAAAEEVHRAVHRVAAGHADLDPSVQRRLLTWLPAGSPGPAGAGAQGLTERELDVLRLIGSGLTNGEIAAYLKVSESTVKTHVNHVFAKIRVRDRAQAVTFAFRNGIAS
>NZ_LT827010.1|WP_014692626.1|6203850_6204270_-|hypothetical-protein
MELHWWSIEVLDGPRLSAARWQDSYGNALVEAAVTHGAFEWQWHRHTWGVLFEIAFRTEERFADYRDLPAVRAALDAVPDPVNGLLIYPGRGGSSGRVQPRRPLPRAGAGAAPIPVEPPRTDVRLGPTEPPVTTAGVTG
>NZ_LT827010.1|WP_014692627.1|6204336_6205704_-|beta-glucosidase
MTDPLALPDFPDGFLWGAATAAYQIEGAVAEDGRGDSIWDTFTRRPEAIASGEVACDSYHRWRDDVALLDDLGVDAYRFSIAWPRVLPAGTGRVNRPGLDYYDRLVDALCERGIRPFVTLYHWDLPQALEDAGGWRVRDTADRFADYATVVAERLGDRVQDWMTLNEPYCSSIVGYAEGRHAPGAVEGHGALAAAHHLLVGHGTAVAALRAASPRARVGITLNLSPSVPATGSAADRAAADRMDLLINRQFTDPVLGRRYPEGFAAMYAGVSDLSFRRDGDLELIGAPLDFLGVNYYYRIHAADAPHTQADPALRSACDIGVRSVARDGVPVTDLGWPIEPQGLYDTLAGLAGRYAGLPPVYVTENGVAQLREGLGEDPERIAFVAGHLEAAAKAAAEADVDLRGYFYWSLIDNFEWARGYGPRFGLVHVDYPTGERTPRASYHWLRERLAGRSG
>NZ_LT827010.1|WP_014692628.1|6205700_6206597_-|carbohydrate-ABC-transporter-permease
MTALADPPATRATPPAVAKRRSRRGFGFPRRGSAWTYAALLAVVAGSLFPLYWSFVVASQTREAVSRTPPALIPGGHLFDNIARVFDSTDFGTALLNSFIVSGSITVSVVFFSTLAGFAFAKLKFRGRQVLLVLAIATSMVPQQLGIIPLYMLMAKLGWTDQLAAVIVPGLVTAFGVFFMTQYLGRAVPDELLEAGRIDGCTTFGLYWHVVLPAARPAAAVLGLFTFMQAWNDFFWPLVVLQNNATVQVALSSLASGYTTDYTLTLTGTLLATMPILVVFLVLGRQIVGGIMQGAIKG
>NZ_LT827010.1|WP_014692629.1|6206603_6207518_-|sugar-ABC-transporter-permease
MAINARLTRLDPQGSPYLYVLPFFLLFGVFGLFPLIYTGYVSFNDWNLLDGGAHQWVGLANYREMLQDSYFWNSLGNTLSIWVLSTVPQLLAALGIAHLLNHKLRARTSLRMGVLLPNITSIVAVTIVFSQIFGRDFGMVNWVLGLLHVGPVDWQAHSWTSHLAISSIVIWRWTGYNALIYLASMQAIPHDLYEAAELDGASSGQQFRRITVPMLRPTIIFTTVISTIGGLQIMAEPLLFGGDYSPTGGSDRQFQTIALFMYEQGFREFRFGYASAIAWTLCLLIAIFAVANFLLTRRIATDEE

Crispr_ID: NZ_LT827010_15

• CRISPR_ID: NZ_LT827010_15
• CRISPR_location: 6284676-6284764
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_15

Consensus_repeat	Method
CCCGCACCGCAACATCGGCCACGGCC	CRISPRCasFinder

spacers of NZ_LT827010_15

>15.1|6284702|37|NZ_LT827010|CRISPRCasFinder
ACGGCCACGGCCACCCGAACCCGCACCCACCACGCCG

CRISPR arrays and Neighbor proteins around NZ_LT827010_15

CRISPR arrays

The CRISPR arrays of NZ_LT827010_15

>merge|NZ_LT827010|15|6284676-6284764|CRISPRCasFinder
CCCGCACCGCAACATCGGCCACGGCCACGGCCACGGCCACCCGAACCCGCACCCACCACGCCGCCCGCACCGCACCATCGGCCACGGCC

>NZ_LT827010|15|13|6284676-6284764|CRISPRCasFinder
CCCGCACCGCAACATCGGCCACGGCC	ACGGCCACGGCCACCCGAACCCGCACCCACCACGCCG
CCCGCACCGCACCATCGGCCACGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_043512346.1|6300701_6302417_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014692710.1|6294998_6295910_-|polysulfide-reductase-NrfD	unknown	unknown	gnl|CDD|309148
NZ_LT827010.1|WP_014692708.1|6291710_6292703_+|selenide,-water-dikinase-SelD	unknown	unknown	gnl|CDD|273100
NZ_LT827010.1|WP_014692703.1|6282629_6284624_-|selenocysteine-specific-translation-elongation-factor	unknown	unknown	gnl|CDD|225815
NZ_LT827010.1|WP_155123644.1|6288917_6291254_-|hypothetical-protein	unknown	unknown	gnl|CDD|379079
NZ_LT827010.1|WP_043515592.1|6282295_6282637_+|nucleotide-pyrophosphohydrolase	unknown	unknown	gnl|CDD|212144
NZ_LT827010.1|WP_014692711.1|6295930_6296848_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|319882
NZ_LT827010.1|WP_014692704.1|6284915_6286202_-|L-seryl-tRNA(Sec)-selenium-transferase	unknown	unknown	gnl|CDD|235278
NZ_LT827010.1|WP_014692706.1|6287550_6288759_-|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_LT827010.1|WP_014692705.1|6286465_6287239_+|aspartyl-protease-family-protein	unknown	unknown	gnl|CDD|133150
NZ_LT827010.1|WP_014692699.1|6280630_6281053_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043515587.1|6273160_6274519_+|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|237233
NZ_LT827010.1|WP_014692700.1|6281075_6281450_-|hypothetical-protein	unknown	unknown	gnl|CDD|226318
NZ_LT827010.1|WP_014692697.1|6278833_6279430_+|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_LT827010.1|WP_014692701.1|6281674_6282127_-|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl|CDD|377129
NZ_LT827010.1|WP_014692709.1|6292740_6294768_-|protein-piccolo	unknown	unknown	gnl|CDD|223021
NZ_LT827010.1|WP_155123645.1|6296849_6300050_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|273689
NZ_LT827010.1|WP_014692695.1|6274507_6276094_-|AMP-binding-protein	unknown	unknown	gnl|CDD|236097
NZ_LT827010.1|WP_014692696.1|6276097_6278737_-|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|236204
NZ_LT827010.1|WP_014692698.1|6279432_6280584_+|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173849

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014692710.1|6294998_6295910_-|polysulfide-reductase-NrfD	gnl|CDD|309148	pfam03916, NrfD, Polysulphide reductase, NrfD. NrfD is an integral transmembrane protein with loops in both the periplasm and the cytoplasm. NrfD is thought to participate in the transfer of electrons, from the quinone pool into the terminal components of the Nrf pathway.	4.35604e-14
NZ_LT827010.1|WP_014692708.1|6291710_6292703_+|selenide,-water-dikinase-SelD	gnl|CDD|273100	TIGR00476, selenide_water_dikinase, selenium donor protein. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelD, known as selenophosphate synthetase, selenium donor protein, and selenide,water dikinase. SelD provides reduced selenium for the selenium transferase SelA. This protein itself contains selenocysteine in many species; any sequence scoring well but not aligning to the beginning of the model is likely to have a selenocysteine residue incorrectly interpreted as a stop codon upstream of the given sequence. The SelD protein also provides selenophosphate for the enzyme tRNA 2-selenouridine synthase, which catalyzes a tRNA base modification. It also contributes to selenium incorporation by selenium-dependent molybdenum hydroxylases (SDMH), in genomes with the marker TIGR03309. All genomes with SelD should make selenocysteine, selenouridine, SDMH, or some combination.	4.44781e-147
NZ_LT827010.1|WP_014692703.1|6282629_6284624_-|selenocysteine-specific-translation-elongation-factor	gnl|CDD|225815	COG3276, SelB, Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis].	1.84684e-77
NZ_LT827010.1|WP_155123644.1|6288917_6291254_-|hypothetical-protein	gnl|CDD|379079	pfam13229, Beta_helix, Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.	0.00177608
NZ_LT827010.1|WP_043515592.1|6282295_6282637_+|nucleotide-pyrophosphohydrolase	gnl|CDD|212144	cd11537, NTP-PPase_RS21-C6_like, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs. RS21-C6 proteins, highly expressed in all vertebrate genomes and green plants, act as house-cleaning enzymes, removing 5-methyl dCTP (m5dCTP) in order to prevent gene silencing. They show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, RS21-C6 contains a single MazG-like domain and functions as a tetramer (a dimer of dimers) with a typical four-helical bundle. Divalent ions, such as Mg2+, are required for its pyrophosphatase activity. This family also includes a pyrophosphatase from Archaeoglobus fulgidus (Af1178). Although its biological role remains unclear, Af1178 shows significant sequence similarity to the mouse RS21-C6 protein.	3.25521e-38
NZ_LT827010.1|WP_014692711.1|6295930_6296848_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|319882	cd10560, FDH-O_like, beta subunit of formate dehydrogenase O (FDH-O) and similar proteins. This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.	8.85899e-140
NZ_LT827010.1|WP_014692704.1|6284915_6286202_-|L-seryl-tRNA(Sec)-selenium-transferase	gnl|CDD|235278	PRK04311, PRK04311, selenocysteine synthase; Provisional.	1.74483e-179
NZ_LT827010.1|WP_014692706.1|6287550_6288759_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	4.65937e-14
NZ_LT827010.1|WP_014692705.1|6286465_6287239_+|aspartyl-protease-family-protein	gnl|CDD|133150	cd05483, retropepsin_like_bacteria, Bacterial aspartate proteases, retropepsin-like protease family. This family of bacteria aspartate proteases is a subfamily of retropepsin-like protease family, which includes enzymes from retrovirus and retrotransposons. While fungal and mammalian pepsin-like aspartate proteases are bilobal proteins with structurally related N- and C-termini, this family of bacteria aspartate proteases is half as long as their fungal and mammalian counterparts. The monomers are structurally related to one lobe of the pepsin molecule and function as homodimers. The active site aspartate occurs within a motif (Asp-Thr/Ser-Gly), as it does in pepsin. In aspartate peptidases, Asp residues are ligands of an activated water molecule in all examples where catalytic residues have been identified. This group of aspartate proteases is classified by MEROPS as the peptidase family A2 (retropepsin family, clan AA), subfamily A2A.	4.96342e-13
NZ_LT827010.1|WP_043515587.1|6273160_6274519_+|glucose-6-phosphate-dehydrogenase	gnl|CDD|237233	PRK12853, PRK12853, glucose-6-phosphate dehydrogenase.	0
NZ_LT827010.1|WP_014692700.1|6281075_6281450_-|hypothetical-protein	gnl|CDD|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	8.9698e-13
NZ_LT827010.1|WP_014692697.1|6278833_6279430_+|TetR/AcrR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.40568e-13
NZ_LT827010.1|WP_014692701.1|6281674_6282127_-|Asp23/Gls24-family-envelope-stress-response-protein	gnl|CDD|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.28949e-10
NZ_LT827010.1|WP_014692709.1|6292740_6294768_-|protein-piccolo	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	8.44787e-16
NZ_LT827010.1|WP_155123645.1|6296849_6300050_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NZ_LT827010.1|WP_014692695.1|6274507_6276094_-|AMP-binding-protein	gnl|CDD|236097	PRK07788, PRK07788, acyl-CoA synthetase; Validated.	0
NZ_LT827010.1|WP_014692696.1|6276097_6278737_-|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|236204	PRK08257, PRK08257, acetyl-CoA acetyltransferase; Validated.	7.54236e-164
NZ_LT827010.1|WP_014692698.1|6279432_6280584_+|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.60572e-130

Protein sequences

>NZ_LT827010.1|WP_014692703.1|6282629_6284624_-|selenocysteine-specific-translation-elongation-factor
MRVVATAGHVDHGKSTLVRALTGMEPDRWAEERRRGMTIDLGFAWTMLGSGTVVAFVDVPGHERFVPNMLAGVGPVPAAMIVVAADEGWRQQSAEHLAALDALGVRHGLLVVTRSDLADPGAATAVARAEIAATSLGAVEAVPVSAVTGAGLPELRAALDRLVGGLPEPDADAAVRLWIDRSFTIRGAGTVVTGTLGAGTLRAGDELALTGMDRPVRVRGLQSLGEPRAAVAAVARVAVNLRGVEKDAVARGAALLTPGRFRLTDLIDVRLHGAAFPTRAMPQPVPGEPPASVTPPVDAQAGRTGLSAGAQGPRPVDARAGRTGLSAGAQGPRPVDARAGRTGLSAGAQGPRQAGVQGLPTAAVDGLPATATLHVGSAAVPVRVRPLGVDTVRLRLGRALPLRIGDRALLRDPGRHLVIAGVTVLDVAPPAVRRRAARVAELATMDGRPDLAGELRRRLLVRGSVLLGMGVPPRSPVAGDWYADPAHWAALRARLRDEVGDYVAGNPLEPGIPIDDLRHRLGLPDRVLVEALVEPPLTIRGGRVGAGPRELPAALLAALEKAFDRERPFTAPEAHRLSDLGLGARQLAAAVRLGLLVQLAPAVVLPAGAPERAADVLTAIPQPFTLSEARRALDTSRRVAVPLLELLDRTGVTRRLADDRRTVN
>NZ_LT827010.1|WP_043515592.1|6282295_6282637_+|nucleotide-pyrophosphohydrolase
MDDVTARVRAFAAEREWQPFHTPKNLAMALAGEVGELLAELQWLTPEQSAAVMSDPDLGPRVRAEIGDVTIYLVRLADVLGIDLIEASLDKLAEAGRRYTVEAARGSSTKIIN
>NZ_LT827010.1|WP_014692701.1|6281674_6282127_-|Asp23/Gls24-family-envelope-stress-response-protein
MNDGFHADRTQEMFLAVAPPVPPQTGGADVIEVAAYRGDTVFEREVIEKLAAAAARSVPGVAELGGDVARFFNAVLDRVGLDKVGDATRGVHARVDGIDVDITVVLCLRAGEVVSEVTSEVRARVIEAVEKYGVQVNNCTVKVDDILMPE
>NZ_LT827010.1|WP_014692700.1|6281075_6281450_-|hypothetical-protein
MTRYLISFNDGAMDHIARAELGDVAEATHAVAQEAMDAGVWVFGAGLERQRASVVATDGVVTDGPYPETKEVIGGFAVVEVATREEALAWAARIAAACRCAQEVREVLPDAVQDEMFRRAGRNR
>NZ_LT827010.1|WP_014692699.1|6280630_6281053_+|hypothetical-protein
MSRTLAIAAALAAACLAAGCSGGSGDDTDKTVAPAAQNSQPAVHSQPDLRASMEAQLGFPPKPDTKAAEAYVADLKSIDPKLVAAHDPEVLVNRGRDQCRDLKTRPQKDWATVASQRFTTPQANAARIIKVVRERLCPTY
>NZ_LT827010.1|WP_014692698.1|6279432_6280584_+|acyl-CoA-dehydrogenase-family-protein
MYADPFETPERGTLREAMATFVRREVVPFLDAWERAGEIPRELHAGAAKAGLYGVGFPEEAGGDGGDTVDMVVATEAFLEAGGSSGAHAALFTHGIALPHMIAAGDPSLIDRFVRPALAGQKIGSLGVTEPDAGSDVGALRTTAVRDGDDYVVNGAKMFITSGTRADFVTTAVRTGGPGAAGISLLVVERGTPGFTVSRKLDKMGWHCSDTAELSFADCRVPAANLIGAEHGGFPLIAQVFVPERIITAVHAYSVAQRCLDLTLVQVRARETFGRPLISRQVVRHKLVEMRQRIELARTFTRRVAARHAAGDWVPGEACLAKNAAVDAGKYVVDEAVQLHGGMGYLRESEVERHYRDIRILGIGAGATEVMADLAAKIFEYDR
>NZ_LT827010.1|WP_014692697.1|6278833_6279430_+|TetR/AcrR-family-transcriptional-regulator
MRRTQAQRSAATRTRILEATCQSLVERGYAETTTAEVQARAGVPRGTLLHHFPTKVDLLVASVQHVARRRLDALTAELAEVTGDGLDAYIDAVWHSFSAPMFWAALELWAAARTDEELRAALLPVEKEIFGVLHERAVAVLGDDPRVPGVTQMTFEVMTGLLMTGIVSGDPVAGELPIRRWKRAAATLLGRASSTRGQ
>NZ_LT827010.1|WP_014692696.1|6276097_6278737_-|enoyl-CoA-hydratase/isomerase-family-protein
MRFRRRSVPETLPVVVPPRRLSRPWALSVTVPATPERVHAYLTHAATMADWMVMHTGWPADPPGVVHGGSRFRQRVRLMGTPVEVRWTVRDAERPRTLWLDGTGPMGIEVGVYLSLAAGEGGTVVRLDGGVQGGPTDGPLGAMVARSLTDALRTSLRRLTAVDLTATGPVIGGPDDAASGRVRPPEKSGKIRHERTGIDLDPWTPVIVGAGQVSDRSSTDDPVTLAVRALREAATDAGRPGLLPMADTIGWVASVSWQYLSAGALIAEAVGATPTHTVQTSLFGGDGPLRLLNDIAAAITRGETSIALLAGAESAATAAAADRAGHPLNWPRQPDGTAPTRILGSDREPNNTPETDAGLVSPLHLYALIENALRARHGRTPQQHQAVITELWSRFADVAATNPYAWLPGPRTPADLATPGPVNRPVCHPYTKLLTANLQVNQASGLIVCSVRAATEAGIPQDRWVFPHAGAHASDAWFVTERDDLTASPAIGAIGRAILAHTGTTINDIRHIDLYACFPSAVQIAAAELGLPLDDPARPLTVTGGLTFAGGPGNNYAGHSVATLVSRLRADPDGFGLATALGWYLTKHAATILSAHPPRAGFRDIDAGLRLPRALRPAASSGSGGTLEAYTVTYHRDGTPATGIVTELGPDGTRIVRTADPASLLDGDPLRPFPRPAALTPVEVAWHGPVTVIRLNRPEARNVVDPLTARALQRAIGDFEADPDARVAVLTGTGPTFCAGTDPETAALGPIGKPLIAAVEGVAVAGGFALALAADLIVAADDALFGLPEVTEGLVAAGLTRLARRLPRAVALELALTGEPMPARRLHDLGLVNRITAPGKAYGQAIDLAVSIAAHPAAAVLLSQRAVAECGGDDLRRKG
>NZ_LT827010.1|WP_014692695.1|6274507_6276094_-|AMP-binding-protein
MSVLENVHAVLRMHQIGIVNLLRPDRLAGAAVRNARLGPQAALIMKAAAEHPHAPALTDERGTLNYRQLDEQSNALARALTELRLPPRSVIGVVARDHRGLVLTISAAARAGLRLALMNTGLAPQQFAEVVARENVRAVLYDSEFAALADAVPDTVPRYLTWADEGAADRTIDMLIAGQPTTPLPLPDRPAGFIILTSGTTGLPKGAPRTRVSPLASALIADRIPFPRQGAIVVASPLFHSTGFGAWTVGLALADHAVLLRRFDAERILRAIADHRASMLVAVPTMLTRILALGPETIARYDTTSLRTVFVAGSPLAPELTNRFQDTFGEVVYNVYGSTEVAVASVAQPAESRRAPGTVGRPPVTVRVALYDDEGTRVTRPHVTARVFVRTGIPFEGYTDGRHKQVIDGHMATGDRGHLDENGLLYIDGRDDDMIISGGENVYPVEVENLLTERDDVIEAAVIGVDDPEFGTRLRAYIVPAEHSARDPQEIRDYVKALLARYKVPRDVVFIDELPRNATGKVLRRLLQ
>NZ_LT827010.1|WP_043515587.1|6273160_6274519_+|glucose-6-phosphate-dehydrogenase
MDKGAQTLVILGASGDLTGRLLLPGLGALVAAGEAPPLTLIGAGMDDWDAQKWRERVTGAFPESPAGKTVIDGTRYVRADVTRSEDLRGLLEGADRPVIFFALPPAVTAKACEALLDVDLPDGTRLVLEKPFGTGANSAAALNRLLTRLVPEERIHRVDHFLGKSTVLNILGLRFANRIFEPLLGSEHVESVDIIFDENLGLENRAGYYDRAGALADMIQSHLLQILALLSMEPPTSLDPQDFRDRTAEALRATRLWGGDPKTASLRARYTAGDLDGRQLPAYADEAGVDPSRETETLAELVLAVDTWRWAGVPFRLRSGKAVGSSRKEAIITFKEPPRLPTGLHGPERPNRLRIGFGPDRFALDFTVNGPGDPFELDPVTLETDFGPGDLPPYGEVLHGVFDDDPLLSVRGDTAEQCWRIVEPVTAAWRDGQVPLVEYPAGSAGPAETLLQ
>NZ_LT827010.1|WP_014692704.1|6284915_6286202_-|L-seryl-tRNA(Sec)-selenium-transferase
MDPRRQIPRTDAVLEDPRLVAAAVRLGREPVKAAVRAAQQRVRDGELDAADVAGAAVAALPETAGGLRTVLNATGVVLHTNLGRAPLSAAAVEAVVAASGHTDVELDLATGRRARRGRGALASLAAAVPRAGAVHVVNNGAAALVLAATALAACREIVVSRGEMVEIGDGFRLPDLLESTGARLREVGTTNRTSAADYAAVVGPQTGFILKVHPSNFVVRGFTSAVAVGALTGFGVPVVADIGSGLLAPDPLLPDEPDADGTLRAGADLVIASGDKLLGGPQAGLLLGDADLVERLRRHPLARALRVDKLTLAALRATVAGPVTPTWAALRYDPDELRDRTGRLAAALDGIPVRVVPSVAVVGGGGAPELQVPSWSLSLPISYAVSLRVATPAIVGRVEHGRLLLDLRCVPPAADPQVAAAIRAVSCE
>NZ_LT827010.1|WP_014692705.1|6286465_6287239_+|aspartyl-protease-family-protein
MDGVPLIVEPDRDEPGCAAVLVDGTIAGRPYRFILDTGAGRTSIVADAELARLPRRGSQQSSGLVGTSTADLLILPELTVGPLSWTGLEVSSTDTGHPDLRNLLGMDAIGAYPGRFDFDRGSWQPAPTGTLPTRRPLDRGARGHILVDVEWPGVTARACWDSGAGITVVGKTFVARHPELFRSAGTSSGIDATGATVEGAAYWMAAARIGGRMFAPHRAVAYDMPAGLDRVDLVLGYPALRQAVWVFDFPARRWSVE
>NZ_LT827010.1|WP_014692706.1|6287550_6288759_-|acyltransferase
MTQAVTAPDPVRAPARPGPNRALNALRAVAAVLVVVYHLRQLLFVDAADAGDGLSTRLLYAVTNMGPAAVVVFFVLSGYWVGGSVFSGFRRDRFRWASYATARLSRLWIVLIPAVALTTILDRVGLALLSGTSIYLGDPAYHHTVPADGLAERLTAGTALGNVFFLQTMAVPTYGTNASLWSLAYEAVFYAVLPLALYAWRGRGGIGKRALSLVLLLGLCALAGPAVLKYLPVWLMGAVVALYREPVRNWLQARSAHWLAWSRAGASAGLTAGLWLAQASYRSVNVLLLATATTVLLALLVEDVGWTGVPGRVLGGLSDYADSSYSLYAIHLPVAAMTAALLTPHVAARWAPTATHWLALAGICAVLTAIGWAFAHATERHTDRVRRIADTLIASVAARTRT
>NZ_LT827010.1|WP_155123644.1|6288917_6291254_-|hypothetical-protein
MIAVPAFRSQVAFAAGSTPPVYSLAATVAPAPMTLADCNDPTCIVAPAPSGNDDYPTLNNLLLLAASRTVPAVLDADNNVVTPATTATVFLGEGTYRVGKVLKLPANVNLRGRGITATTVSMITANNVNFTYASIISWDFNHQIAGATSNLVSDLTVNGNCREGAGQPVPSDMPGRPGEFCDFRGADGKAASTNSGGGVSVGDNWTVRQVRFTNLEYFKVWVGNGVTNVRIVDNRFDNWGGAESGDEDNVGGGSRNDGVIVEYNQFDKTIRGNSFDFTNAIRTTVRNNVVRSDGTIATARKDTSLYGNMYFEGIQQATVTDNVLWGAQIALKSNSLYAHSGENRDITDPRDSIVSGNRISYSGETGISVTYDDYKDGPNASNLGQPGSWTDKSAPTDAFHVVRPGGNNVVRDNVIEYTGRSGIMVNGSYASAKNAADTITGNVIHNAGWGGSTVYDSGAGYFDTAGIGLSIGVGDQVYGNTIEDYPAKKTTWYGIDLGARRASTSPTGTVLTGPAGEVNTVTNVIGTAYHDQTRISEAVTNLSAGGKVLNWDEAYPLDGRPIRGYRIYRDGNVVGDLPIGSVSIPNNIMTADESNFENASAGTAGWVAGTRTTLARVAGNSSRGTASMTLTSSGTGEVSFSGRKINVTPGQVYTSVLSARAMSTAAAGKQVRAGVKITFANGTTQKWATNNKTAIDSYANWITSYYTFSVPADAVSVEPWYLIEGTVAGDAHMVDRLGLVAGTRTEQFTEANGPANAVYHVVSYTADDNSMPQSVVVP
>NZ_LT827010.1|WP_014692708.1|6291710_6292703_+|selenide,-water-dikinase-SelD
MTVRLTQYAHGGGCACKIPPGELEQIVAGLTGPDQQAGGDLLVGLDDGDDAAVVRIAAGTAVVATADFFTPVVDDAYDWGRIAAANALSDVYAMGGRPVVAVNLLGWPRDVLPLELVTEVLRGGLDVARQAGCHVAGGHSVDDPEPKYGMAVTGVADPDRLMRNDAGRPGIPLTLTKPLGVGVLNSRHKQTGEVFPQAVAAMTTLNRAASEAALAAGVVCATDVTGFGLLGHLHKLARASGVTARIDPAAVPYLDGAREALAGGFVSGGTRRNLDWVRPHADTAGVSEDELLLLADAQTSGGLLVAGELPGWPIIGELLPPEDGVTVVVR
>NZ_LT827010.1|WP_014692709.1|6292740_6294768_-|protein-piccolo
MTQPDKPSEKVPEQPDTDKPEIERPETVEPTPEAAQPEATATPEAPEDKREAEPESEPEHEEAAEPADEPTAAEPTAAEPTAAEPADEPTAAEPTAAEPTDERAAAEPTTALPEPPADPATAAAMAAAPTPQQPGWPAPQQGGPGWPAPQQGGWQPPAPPQPGWPQQPVPLQGWPQQPVPPQGWPQQPVPPQAGWPQQPVPQPGGWQPPAVLLGPPAPPREPAKTDRLAAALGNASFLSLGYFLMRRTVLGVLTLLASLILLLGIVPAVHTGWIEIVAVLWWIAMIVHGWFLARGPVEPATRTRQRIVGIAAAAVVLLLLGGLRVQAATIGSAVDDAKAAGDCGGAVSKLDKLWFGLRVADGPMAAEGDDTVEACRQLNEADETLTGMLTAPSATGLTAGFDQINTVLTRFPGHEKMADAVLDGFLGKLPLSDACGTATITSWLAKRPKTNNTLDRSAEVVAKHEPAALAGCGDTYLNGQQWESAKVVYQQLIDTYPTDVNKPKAEEGIAKADLAIEFDAFKDATDSVSGNYCDTPVKYSAAKAYGKGVNRAMVFGNDTEAKRLPGGWKTTDPTVANLVLCVSGDSQGAAVRSCDYGSAGQHRVTFHKVKVTVRGYEVRSGKQIFSKTLQFSGTSCPHRIEYMTTLGVDLGPPRHMDVKVDANDVQAQFKPLIVK
>NZ_LT827010.1|WP_014692710.1|6294998_6295910_-|polysulfide-reductase-NrfD
MVPKAEFRSYYGRPIVRPAVWRHDIAAYLFTGGLAAGSAMLAAGGDATGRPALRRAGRATALGALVASTYFLVNDLGRPERFHHMLRVAKPTSPMSMGTWILSAFGAAAGVAAAAEVAPRVPGLRQLGTAGQYGAAAVAPALATYTAVLLADTATPSWHAAYPELPVIFAGSALASGAGVGLIAAPTEQAGPARRMAALGAALELYGAHRIGTAKGILSEPYAVGRPGRLLRAGRVLTAAGAVGAVLGRRSRVVSALSGLSLLAASVATRFGIFEGGVASAKDPKYTVVPQRERLVRRSGEAA
>NZ_LT827010.1|WP_014692711.1|6295930_6296848_-|4Fe-4S-dicluster-domain-containing-protein
MAGNSLYGPLDPAPDAGYPDAPPRMGFFTDTSVCIGCKACEVACKEWNGVPDDGFNLLGHSYDNTGGLSANSWRHVAFVEQPVDHRNVDVFAEAAGPQFLGMPSRDLPGRTMDAPRTDFRWLMMSNVCKHCTHAGCLDVCPTGSLFRTEFGTVVVQEDICNGCGYCVPACPYGVIDQRHDDGRAWKCTMCYDRIGDGLTPACAKACPTESIQYGELEELRGRARQRVATLHEQGVAEARLYGHDPDDGVGGDGAFFLLLDEPEVYGLPPDPIVPTRDLPKMWKRAGLAGLAMAAAVVVSFLGGRP
>NZ_LT827010.1|WP_155123645.1|6296849_6300050_-|molybdopterin-dependent-oxidoreductase
MGVRTWIEGWPVYRQLTGTDPLGRGAAVQSPRSKSLTARTETADSMARSVCPYCAVGCGQRIYVKDGAVTQIEGDPDSPISQGRLCPKGSASKSLVTSDRRQQKVLYRRPFGTDWEELDLDTAMDMIADRLLKAREDTWEDTDDEGRPLHRTLGFSSLGGATLDNEENYLIKKLFTAMGALQIENQARIUHSATVPGLGTSFGRGGATGFLQDLANADCIVIQGSNMAEAHPVGFQYVVEAKNRGAKVIHIDPRFTRTSALAHTYVPVRAGADIAFLGGVINYILSNEKDFREYVVAYTNASMIVSEDFRDTEDLDGLFSGFDPETKAYHQGSWAYEGQQDDDSVQDHGESHTDRETASGLEQESHGPPIPADVPRDPTLQHPRCVYQILKRHYARYTPEVVERVCGVSPEQFREVCEAWTANSGRERTTALVYSVGWTQHSVGVQYIRTGAIIQLLLGNMGRPGGGVMALRGHASIQGSTDIPTLFNLLPGYLPMPHHQQHETFRQWVDAIRHPEQKGFWADAEAYAVSLLKAYWGDAATAENDWGYDWLPRLTGDHGTYQQVLDMIDGKIKGYFLLGQNPAVGSAHGRAQRLGMANLDWLVVRDLFMIESATFWKDGPEVATGEIVPGECKTEVFFLPAASHAEKEGTFTQTQRLLQWREKALDPPGDCRSELWFFYHLGRLVRERLAGSTLPRDQGILNLAWDYDPDDGEGVLKEINGFDVATGEPLPGFSALKADGSTACGCWIYSGVFKDGVNQAARRKSRKEQDWVAAEWGWAWPMDRRTLYNRASADPDGKPWSERKKYVWWDAEAGEWTGYDVPDFEKTKAPDYRPPEGATGVAAIAGDDAFIMQGDGKGWLYAPSGLIDGPMPTHYEPAESTVHNPLYAQQANPTRKTYDRPDNQLNPVSETFPYVFSTSRLTEHHTAGGMSRQLAYLSELQPEMFVEVSPQLAAERGLDHLGWAHIVTARAAIEARVLVTDRIRPLRVDGRVLHQIWMPYHWGGSGLVTGDSANDLIGIVLDPNVLIQESKVGTCDIQPGRRPVGRELLDYVADYRKRAGLRTEGH
>NZ_LT827010.1|WP_043512346.1|6300701_6302417_+|hypothetical-protein
MHSLLIFLALLIAATAAGGLLFLRKEPDRAPDPKLAATQAATALREQDAAALKVSFFDQSGLDVTGDLTIARGGATAGTLTDSGGGRADYLASGSEAAVRGDQDWWARRDPARIGVLKDAWVRPEHYAFPLDGAGLDPGALAGLVDWVRAAGASAPDADSVAGKPAVGLRRDGWTVLFSRSRPYRLLWFGGPLQNGTPLAPTINGSPSAPTPPYVSVLVDPKAPAVPQVTVPDAREEQKTPARLPAFDVTVNAATCRTVTCSWTVTATNVGKVACDASVIASVTPGMPETRVAALGTVPPGASRTTARMTFPNPAPTNRNVSADYRAQAYCPEIYGPNLKLMRRLQERGLVPGRSPTLSRLDPSQMPAMLFTLDAMAGAGRFDADRATEEMEKAITAGALPEIGELVQSRRLANPEVLYGKLANLIFEYDTAAPGTPVREKTGYRRELQIAAGILRQDRDATVTLDGGGIDIVVRTAGSPTYAIQAKSVSSESIAENLRRAAEDLRAHAPAGASKVALLYVEAPAGYAHAAGRDRFEREFTAVNADTCAAGLDRIEIVNQGGDQRFPGCTR

Crispr_ID: NZ_LT827010_16

• CRISPR_ID: NZ_LT827010_16
• CRISPR_location: 7162311-7162401
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_16

Consensus_repeat	Method
GGCGGACCGCGAGCGGCCCGCCCTCCGAA	CRISPRCasFinder

spacers of NZ_LT827010_16

>16.1|7162340|33|NZ_LT827010|CRISPRCasFinder
GCCCCCCGGGTACGGGGCGACCGAGACAGGAAA

CRISPR arrays and Neighbor proteins around NZ_LT827010_16

CRISPR arrays

The CRISPR arrays of NZ_LT827010_16

>merge|NZ_LT827010|16|7162311-7162401|CRISPRCasFinder
GGCGGACCGCGAGCGGCCCGCCCTCCGAAGCCCCCCGGGTACGGGGCGACCGAGACAGGAAAGGCGGACCGCGAGCGGCCCGCCCTCCGAA

>NZ_LT827010|16|14|7162311-7162401|CRISPRCasFinder
GGCGGACCGCGAGCGGCCCGCCCTCCGAA	GCCCCCCGGGTACGGGGCGACCGAGACAGGAAA
GGCGGACCGCGAGCGGCCCGCCCTCCGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014693455.1|7151390_7153019_-|beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|119333
NZ_LT827010.1|WP_014693457.1|7154427_7155684_+|amidohydrolase/deacetylase-family-metallohydrolase	unknown	unknown	gnl|CDD|236423
NZ_LT827010.1|WP_014693453.1|7149208_7150399_-|alanine-racemase	unknown	unknown	gnl|CDD|143492
NZ_LT827010.1|WP_014693465.1|7163527_7163779_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_080128102.1|7166332_7169047_-|cyanophycin-synthetase	unknown	unknown	gnl|CDD|237586
NZ_LT827010.1|WP_014693472.1|7172406_7173105_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293792
NZ_LT827010.1|WP_014693469.1|7169979_7170468_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|224647
NZ_LT827010.1|WP_014693456.1|7153093_7154431_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197713
NZ_LT827010.1|WP_014693462.1|7159606_7161175_+|amidohydrolase-family-protein	unknown	unknown	gnl|CDD|237304
NZ_LT827010.1|WP_014693471.1|7171075_7172386_-|histidine--tRNA-ligase	unknown	unknown	gnl|CDD|234586
NZ_LT827010.1|WP_014693464.1|7162409_7163312_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|224112
NZ_LT827010.1|WP_014693470.1|7170524_7171046_+|PaaI-family-thioesterase	unknown	unknown	gnl|CDD|239527
NZ_LT827010.1|WP_014693454.1|7150449_7151367_+|phosphotransferase	unknown	unknown	gnl|CDD|309685
NZ_LT827010.1|WP_014693460.1|7158903_7159206_+|urease-subunit-gamma	unknown	unknown	gnl|CDD|376347
NZ_LT827010.1|WP_043515946.1|7161184_7162228_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176221
NZ_LT827010.1|WP_014693468.1|7168937_7169825_-|cyanophycinase	unknown	unknown	gnl|CDD|131124
NZ_LT827010.1|WP_014693461.1|7159202_7159610_+|urease-subunit-beta	unknown	unknown	gnl|CDD|376370
NZ_LT827010.1|WP_014693458.1|7155683_7156064_+|RidA-family-protein	unknown	unknown	gnl|CDD|223329
NZ_LT827010.1|WP_014693473.1|7173253_7174123_+|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|238194
NZ_LT827010.1|WP_099343917.1|7164111_7165959_-|protein-kinase	unknown	unknown	gnl|CDD|270916

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014693455.1|7151390_7153019_-|beta-N-acetylhexosaminidase	gnl|CDD|119333	cd06563, GH20_chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. This GH20 domain family includes an N-acetylglucosamidase (GlcNAcase A) from Pseudoalteromonas piscicida and an N-acetylhexosaminidase (SpHex) from Streptomyces plicatus. SpHex lacks the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_LT827010.1|WP_014693457.1|7154427_7155684_+|amidohydrolase/deacetylase-family-metallohydrolase	gnl|CDD|236423	PRK09237, PRK09237, amidohydrolase/deacetylase family metallohydrolase.	4.05009e-137
NZ_LT827010.1|WP_014693453.1|7149208_7150399_-|alanine-racemase	gnl|CDD|143492	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase. This subfamily is composed of Burkholderia cepacia cryptic D-serine dehydratase (cryptic DSD), which is also called D-serine deaminase, and similar bacterial proteins. Members of this subfamily are fold type III PLP-dependent enzymes with similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as dimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on similarity, it is possible cryptic DSDs may also form dimers. Cryptic DSDs are distinct from the ubiquitous bacterial DSDs coded by the dsdA gene, mammalian L-serine dehydratases (LSD) and mammalian serine racemase (SerRac), which are fold type II PLP-dependent enzymes. At present, the enzymatic and biochemical properties of cryptic DSDs are still poorly understood. Typically, DSDs catalyze the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia.	2.62077e-142
NZ_LT827010.1|WP_014693468.1|7168937_7169825_-|cyanophycinase	gnl|CDD|131124	TIGR02069, cyanophycinase, cyanophycinase. This model describes both cytosolic and extracellular cyanophycinases. The former are part of a system in many Cyanobacteria and a few other species of generating and later utilizing a storage polymer for nitrogen, carbon, and energy, called cyanophycin. The latter are found in species such as Pseudomonas anguilliseptica that can use external cyanophycin. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. [Energy metabolism, Other].	9.22039e-67
NZ_LT827010.1|WP_080128102.1|7166332_7169047_-|cyanophycin-synthetase	gnl|CDD|237586	PRK14016, PRK14016, cyanophycin synthetase; Provisional.	0
NZ_LT827010.1|WP_014693472.1|7172406_7173105_-|MBL-fold-metallo-hydrolase	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	2.84699e-64
NZ_LT827010.1|WP_014693469.1|7169979_7170468_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	7.03261e-31
NZ_LT827010.1|WP_014693456.1|7153093_7154431_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	7.94062e-05
NZ_LT827010.1|WP_014693462.1|7159606_7161175_+|amidohydrolase-family-protein	gnl|CDD|237304	PRK13206, ureC, urease subunit alpha; Reviewed.	0
NZ_LT827010.1|WP_014693471.1|7171075_7172386_-|histidine--tRNA-ligase	gnl|CDD|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	3.79373e-114
NZ_LT827010.1|WP_014693464.1|7162409_7163312_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|224112	COG1191, FliA, DNA-directed RNA polymerase specialized sigma subunit [Transcription].	2.72296e-54
NZ_LT827010.1|WP_014693470.1|7170524_7171046_+|PaaI-family-thioesterase	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	2.38271e-32
NZ_LT827010.1|WP_014693454.1|7150449_7151367_+|phosphotransferase	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	2.00407e-35
NZ_LT827010.1|WP_014693460.1|7158903_7159206_+|urease-subunit-gamma	gnl|CDD|376347	pfam00547, Urease_gamma, Urease, gamma subunit. Urease is a nickel-binding enzyme that catalyzes the hydrolysis of urea to carbon dioxide and ammonia.	2.9537e-55
NZ_LT827010.1|WP_043515946.1|7161184_7162228_-|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176221	cd08260, Zn_ADH6, Alcohol dehydrogenases of the MDR family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. This group has the characteristic catalytic and structural zinc sites of the zinc-dependent alcohol dehydrogenases. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	6.84772e-174
NZ_LT827010.1|WP_014693473.1|7173253_7174123_+|peptidylprolyl-isomerase	gnl|CDD|238194	cd00317, cyclophilin, cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the immunosuppressive drug cyclosporin (CsA). Immunosuppression in vertebrates is believed to be the result of the cyclophilin A-cyclosporin protein drug complex binding to and inhibiting the protein-phosphatase calcineurin. PPIase is an enzyme which accelerates protein folding by catalyzing the cis-trans isomerization of the peptide bonds preceding proline residues. Cyclophilins are a diverse family in terms of function and have been implicated in protein folding processes which depend on catalytic /chaperone-like activities. This group contains human cyclophilin 40, a co-chaperone of the hsp90 chaperone system; human cyclophilin A, a chaperone in the HIV-1 infectious process and; human cyclophilin H, a component of the U4/U6 snRNP, whose isomerization or chaperoning activities may play a role in RNA splicing. .	4.5708e-24
NZ_LT827010.1|WP_014693461.1|7159202_7159610_+|urease-subunit-beta	gnl|CDD|376370	pfam00699, Urease_beta, Urease beta subunit. This subunit is known as alpha in Heliobacter.	8.64616e-56
NZ_LT827010.1|WP_014693458.1|7155683_7156064_+|RidA-family-protein	gnl|CDD|223329	COG0251, TdcF, Putative translation initiation inhibitor, yjgF family [Translation, ribosomal structure and biogenesis].	2.20205e-36
NZ_LT827010.1|WP_099343917.1|7164111_7165959_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.52255e-107

Protein sequences

>NZ_LT827010.1|WP_043515946.1|7161184_7162228_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MRAIVIDSARARPEVREVPEPTAPPGGVVVRVMATGLCRSDWHGWAGHDDDITFPHVPGHELAGEVTAVSPGVTRWQPGDRVTVPFVCGCGRCDWCRTGQAQVCPAQQQPGFTHAGSFAESVALHAADTNLVAIPAGVSFTTAASLGCRFATAYRGLAGRARVTAGEWVTVVGAGGVGLSAVMIARALGARVIAVDRNPRALAAAAAIGAGHTVLTGAGVDVPGAVAELTDGGSHVSVDAVGSEQTCADAILALRRQGRHVQIGLLPPVGGHPRVPMSRVIGWELDVLGSHGMAAADYPAMMALIEQGRLRPDRLIERTVGLGEAAALLPGFDQATVAGMTMIDPAR
>NZ_LT827010.1|WP_014693462.1|7159606_7161175_+|amidohydrolase-family-protein
MTSLDRGRYAALYGPTAGDRIRLADTDLLLEVEEDRSAGPRPGDEAVLGVIRESVGQSRAARADGTPDTVVTGVVVLDHWGVVKADVGIRDGRITAIGKAGNPDIMDGVHPDLVIGASTEIITGNGRILTAGAVDSRAHLIRPAVLDAAVAAGITTVVGGGTGPAEGARGATVTPNVWHLARMLAAIDTFPVNVLLLGRGDTVSPEAMWEQLRGGAGGFALHEDGGCTPAAIDACLRVCDASGVQAAIHAGTRNEAGSVDDTVRAIGGRPVHAGAAAAMITVAAQPNVLPSSADPAGSATPATDLLHDLGAVSMIGSGATGRPGEVILRTWRTAHAMKAWRGPLAGDGSSDNNRIRRYVAKYTICPAIAHGMAAQVGSVEPGKLADLVLWDPAFFGVRPVLVLKGGMIAYAQTGDAAASTLPPQPAMPRPMFGAHGVVPAHTSLAFVAPAAIDALLSDRIGVRRALVPVGDTRAAGKADLPLNDAMPRIEVHAGSGEVRVDGEVVQPQPVTEMPLAQRYFLF
>NZ_LT827010.1|WP_014693461.1|7159202_7159610_+|urease-subunit-beta
MIPGEVLAGDGDIVINPGRVTRDLTVRNTGDRPVSVGSHFHFAEVNTALEFDRAAAWGHRLAVPAGTSVCFDPGAAREVVLIPLAGNRVVPGLRGLAGGPLDTLPPPAEPDPADIEPAGSLDEDTGEAQPNGSPR
>NZ_LT827010.1|WP_014693460.1|7158903_7159206_+|urease-subunit-gamma
MFLSRHEQERLLIHVAADVAQKRRDRGLKLNHPEATAIITAFLLEGARDGRSVDELVAAGGRVLTRDDVLPGVPEMIAEVRVEATFPDGPRLIAVPGPIA
>NZ_LT827010.1|WP_014693458.1|7155683_7156064_+|RidA-family-protein
MPKRAVMTDKAAPVGGPYSHAVVAGDTIYLAGAIPALPDGTRVTGTFAEQAHAAFRNLAAVAEAAGASLDDAVRVGVYLRDFGDFAEMNEIYQQYIKGEHRPVRTTLPVPLVGFDIEIDAILYVGD
>NZ_LT827010.1|WP_014693457.1|7154427_7155684_+|amidohydrolase/deacetylase-family-metallohydrolase
MTFDILLTGGTLLPAGPGPAGVRRNIGDVAIRDGRIAAIGPALPRDAHRVVDVSGRLVTPGLIDLHTHVGPGYWGIDPDPVAWHSGVTTWVDAGSAGAYTLDGLRRVAAAATVRVPALLNISAIGLAGRTGESRDLATCDVPLAIDTIQTHRELIRGVKVRIDRDTVGDNGIEPLRRGLTAAEACGVPVMVHIGTAPPRLDEVLDLLRPGDIVTHCASGIAAPLGPAVHAAAGRGVLLDLGHGSGGFAFDVLQAQLDAGLMPHTVSTDLHARSLYGPVFDLPTTMAKLLAVGVPLPEVIAAATVHPARALGLPGGTLAIGAPADLAIFRVRDEEFPVVDAHREVRISPVRLVNEATYVGGALLPPRLPAPPAPWIPLTEAQRAALDQRARHIRDLLATPLVGVDGLAEQFPRDQPRSS
>NZ_LT827010.1|WP_014693456.1|7153093_7154431_+|helix-turn-helix-transcriptional-regulator
MIIGIVVHSGQRGRFTEAARTLTGVSFAWAVYEREEEIRDRVTTLLAAGPLDGLLLGPVPHARAGDLVPPGLPVAITRAAALDLALAWARARGNGWPATPVSIDTFPDETVTEVADALALDRSAIATLPFRPEQPIAEVVAFHQEHLARTAAPYVITVRTGVAAALDGRTAVLQAMATPGTVRADLHDLVSRVRGQQADGQRFAAAVFRAPAPGAREALRQALSALPELADAWIDEHGPRAVIAFAPAGVFETLTSHWVSLPGGFHRGRRDHGQPGEPPAAEPDATVEDPAGPAVGFGIGASARSSVALAEQAADRAERAGSTSGYLITEDGVMIGPIGAADPPLAYSYREHGGLEELAVRAGLSAATMSRLAALERSLAGRAITPGELARALGITDPSGRRLIRKLGEAGLVAGEGSAQPHHKGRPTRLYRLTIQAALTAGGAG
>NZ_LT827010.1|WP_014693455.1|7151390_7153019_-|beta-N-acetylhexosaminidase
MNEPLTSIVPRPARVTSGEGAFHLGPGTALDAGPALTGVAAWLRGALGRVIGGHLLPGPDGIRLRTVPELAPEAYQLEVRDTGIEIRGGSPAGVFYGAQTLRQMLPPVTLRRARLTDGPWTIPAGRVDDAPRFPWRGVMLDVARHFMPVADVLRLIDLIAFHKLNVLHLHLTDDQGWRLEVPGRPRLTSIGAWRPATMLGSRRHERFDARPHGGFYSDDDLREIVAYAADRHITVVPEVDMPGHMQAAIAAYPELGNGFSGDVRAGWGISPHVLNLGPEALDFCRTVLDHLCDLFPSELIGIGGDECPADEWHDSPVAQARIRAEGLGGPDRLQPWFTTRMAGHLATRGRRVFGWDEILAGGAPPGAVIAAWRGPGPAAHAARAGHPVVSCPDMSVYLDYRQSDDPGEPTPVGTRLTIEDVFAFDPVPPGLTPAETALVRGGQANLWTEHMESARRVDYQAFPRLCAFAEAVWGPAERDFTEFIRRLPAHLERLDALGVNYRPLSGPRPWDARPDAPGNPRTRNDRLAELREMTADLERERS
>NZ_LT827010.1|WP_014693454.1|7150449_7151367_+|phosphotransferase
MVEIALPDSFTRRVAQCWGAPGTRWLADLPEIATRVLHDWDLHLDRPCPLSLNWVTRVRRADGSAAVLKMGIPGADHLSDEAAALEFFAGRGAVSMLAHDAARGAILLEEVRPGRPARSLVPDRDEDATAALIGVIRGLHRPAPPGIALPELAARRATFDEHLRRFPDDGPLPRHLVERAGRLLTELCETAIERVVLHGDLHHDNVLAAGREPWLVIDPHGLTGDPGYEIGAMLYNPYPMDDDTVLRLVPGRIEQLADGLDIPIERVVAWGFVQAVLSEVWNATGDGIATGRPLRLASLLLPRLP
>NZ_LT827010.1|WP_014693453.1|7149208_7150399_-|alanine-racemase
MTIDWRSKGFWLPHGGRTAEQIASERPSIFGGGFTWPLLVIRQAAVEANIATMAAYCRRHGCDFAPHAKTTMAPGLLEAQLRAGAWGLTVATANQALVLRRLGVQRVLIANQVLDPIALRWLAGESDAGWEVYFQVDSLAGVRAAAAAGRIRVLVELGHPGGRTGVRTLDELDRVARAVAAAPGVELAGLTGYEGQLADLAEVDTYLDRLAAGFEQLSAAGLLPEEPIVSAGGSAWFDRVTDRLKALAPRARLILRSGASVTHDDGFYRERTPFVRVPGEGPLTAALEVWAQVLSAPEPGLALAGMGKRDAPFDEGLPVPGEVRRPDGTTAPADGLRVTRLNDHHTYLQVADGTVVEPGDLVRFGISHPCTAFDKWRDIPVVDEQRRVVDVLHTYF
>NZ_LT827010.1|WP_014693464.1|7162409_7163312_-|sigma-70-family-RNA-polymerase-sigma-factor
MTATTELPATIGVIHDAPSARDIEDLIREHMPMVGHLVRELLNRVPGHVHADDLSSAGFAALLGAARSFDVTRGIPFHRFAAVRIRGALLDELRGQDWASRSVRARARRAATARQELTAALGRTPSDAEVAEMLGVGISELASVEDDVQKASLLSLQGFPTGAAEEMVPELSEGPEDLLLKRERLGYLHQAIQALPERLRQVVEESFLQEQPLSEVAARLGVTESRISQLRTEALRLLREGLNSSLAPELLTVAAGGPRTRKGCLQRRRSEYFAKVQQQGNLHTRLALTDSHGVPIAVAA
>NZ_LT827010.1|WP_014693465.1|7163527_7163779_-|hypothetical-protein
MISIVKDLAAEALFVSCLQPSEYPTRRALEDAITSTLLQYGSDGCAAGVAAEFGDHPDIAVRRMRWVQAELAEVITFRAPALH
>NZ_LT827010.1|WP_099343917.1|7164111_7165959_-|protein-kinase
MSTADLPGSGLLAGRYRLVERLGAGGMSVVWRGFDEVLGRQVAVKVLPPSTSADPSFRRRLRAEAQAAARLSHPHITNVYDYGEASTVDGEPVPYVVMELVDGESLAAVLARVRTLPWNQAVRISADVAAALAAAHARGIVHRDVTPANVMLTPAGAKVVDFGISALIGENDTDPDGSLLGTPAYLAPERLEGGQVSPATDVYAVGLLIYRMLIGQLPWDVGTTTALLRAHQYVEPDPLPPVDGLPREVDALVGRCLEKRPADRPPTAEVAHLLAGVAAGAQAAAATGFRGDWEDSGEDTTILPSGYPYAGMGPAAAATAPPALRPGGAVSPSAPADDRSPAPGRRQVRTRRALVVAGTIAVMSALTYGWSLAAPGAGDKRADAVTPGPSVVPAAGNCIVSYAVWSQEKGRFKAQVTLANRGDKPVDDWQLWFLMPGDQILSGRSLTQDQRAVTVHSASTLAPQQNTTVEIAGRFAKSNAAPMLFQLNGKTCQAYVSSSPGQPSRPVEQLSDGSVRLGDPASDSTPAPGISIDPVGIVHITPSTLPARPSTIPLPGSSSTATGGGGSTKPSDGASDTVQPEPAQSPTSKAPVEQPSNPPPGLPGASLDGCDSQDC
>NZ_LT827010.1|WP_080128102.1|7166332_7169047_-|cyanophycin-synthetase
MKIESLRRLRGPNVYLSRPAVVARLRLEELTGRETSDVTGFTERLLRALPGLAEHHCAAGAPGGFVSRLRGGTYFGHVTEHVCLELSQLIGRDVSFGRTVSAGEPGLYDVILECPVDESPESRVPGELLEAAVDLVLAVQAGQAGQPPRLAELAALAEREATGPSTRAIIAAARRRGIPVERFDDLSLVRLGWGTRRRMAWAAMTDRTSGVGIDIAGDKHVTRCLLGEAGIPVAAGGAATTVEEAVRLLDELGAPVVVKPRQGRQGRHVVLGLGTREAVERAFGEAGGDVVVERQLAGRDYRVLMVAGEVAAAAERIAAHVVGDGTTTLAGLVERTNADPRRGPGHSRVLTRIALDEVALRVAGIGPDDVPAEGETVWLRECANLSTGGTSRDVTDQVHPDVTRLCQRVVALVGLDIAGIDLRLPDIGAPLPPAGETEPAGGVIEVNAVPGLRMHLAPVRGRSRDVGDAIVRAMFPGGSDGRIPTVAVTGTNGKTTVTRLTAHLLGGGGHRVGAATTDGVFVDGRAVYLADATGPRSAQQVLGDPQVDIAVLETARGGLLRRGLGYDWSDVGVITNITADHLGQDGLDSIEDLAHVKAVVAERVRDGGTLVLNADDPWVRSLASRPRVRADRKRLVWFGLDPGNPVLTEHLGRGGTAYLLQDGWLVQATGARRTPLLRVAEVPGAYGGAALHGAANALAAIAAARALGARPETVAARLSEFDPGVDNPGRGTLLRLGDVSVFLDYGHNPAALAATLRTLHRLWGANRCVAAVTLPGDRRDDLLAASAQILADGLTRAVLYDDQDRRGRAPGEVPALVEREMRARRPNLRAVRANGFREAVTTALDLAETGDVVLVIYEKWGPMRAFLTELGAGPAGARPMTPVTAAVRAIPQLVSSSVTDHGHF
>NZ_LT827010.1|WP_014693468.1|7168937_7169825_-|cyanophycinase
MDARLLLIGGAAGPALLIRFVELAGSASARIVVIATASAEPAVAEESSVGAFRQLGAGSVRALRLASRADANAPAAAAALREATGIFFTGGDQRRITTVLGGTATDSLLQELVAGGTTVLGGTSAGAAMMSATMIIGGDGPGVTAASVQTGPGLEFLPGVLIDQHFAQRGRLNRLLSAVALYPHELGLGIDEDTAILTDGDRFEVLGSGAVTVVDAGAATDIRVPPSGPIALAGVRVHVLPAGHTFHLTGRRPGIGDTPHEDREPAPPARPQRVSVPAGGGGPVAPGGADRPGDL
>NZ_LT827010.1|WP_014693469.1|7169979_7170468_-|helix-turn-helix-transcriptional-regulator
MVSHVTPPEALDWDVDNCTISRAMEILGEKWTMLVLREIFSGIRRFDDMRVRTRIPRQVLANRLTALVAAGVLRREPYQEPGARVRHEYRLTEKGFDLYPVLIALAGWGNRYLADPAGPPIQFVHRECAAEVDVAIRCADGHDVTDHRDVLPRPGPGARRRG
>NZ_LT827010.1|WP_014693470.1|7170524_7171046_+|PaaI-family-thioesterase
MTQTQASLVASRTRTFSWTDPAEHARLFVERSGLEVLQAMAAGEVPPPPIFQLIGGNRLEVEPGSVTITLDPQEFHYNPIGTVHGGIIATLLDTAAACSVQTTLPAGIGYTSMDLNVKFLRAVTVNTGLVRCTGTVLQSGRRTALAEARLTDARGRLVAHATSSCLIFDLPKA
>NZ_LT827010.1|WP_014693471.1|7171075_7172386_-|histidine--tRNA-ligase
MPISGFPEWLPPQRMIEQYALDKIRSTFELYGFAPLETRAVEPLETLLSKGETSKEVYLLHRLQEDESGKREDQLGLHFDLTVPFARFVVENHGKLVFPFRRYQIQKVWRGERPQEGRYREFLQADIDVVNRDTLPFHFDTEMPLVIGDVFRSLPIPRATILVNNRKVCEGFYRGLGLADTAQVLRTVDKLDKIGPDKVAAALVETAGATDAQAAACLKLAGISAADASFVDAVRALGVSDPLLDEGLAELEQVVVAANEHAPGLIRAELKIARGLDYYTGTVYETQLQGYERFGSICSGGRYETLASVGNTRFPGVGISIGVSRMLGLLFGQNAVSVSRTVPTCVLIALPSEEQRSVSERTAAALRRRGIPTEVAPTAAKFGKQIQFADRRGIPFVWFPGEPDTVKDIRSGEQVEADTATWTPPAADLHPVVTGA
>NZ_LT827010.1|WP_014693472.1|7172406_7173105_-|MBL-fold-metallo-hydrolase
MLVASFPAQAFGTNCYVVAAGPGEQCLIVDPGIGVLDRLDEVLAQHRLSPAAVLLTHGHLDHTFSVAPVCGARGITAYVHPDDREMLADPSKGLSTDLSSLFGGRLQYSEPDDVAPLTDGAVLSLAGLQVTVDHAPGHTGGSVLFRLPGAGSSWDAEELCLSGDVLFAGSIGRTDLPGGSTPTMMASLRDKILPLADDTVVLPGHGPATTIGRERASNPYLRDLTAAPGRFL
>NZ_LT827010.1|WP_014693473.1|7173253_7174123_+|peptidylprolyl-isomerase
MAPSKDRQRKLARAKYDRQMARRAVRERQRRRVLAGAGTALAVVLVVAAGLWIGGVFDGKGKSTTTEAQDDCIWTPFDKSKNANLKEVGTPPTKNVPQTGTEQMTVTTDLGAPLVATLDVASAPCAAASFSYLAGKQFFDGTPCHEVLDIGAVHCGDPSGTGLGGPTYSYYDENIPDRPAPSASAGAGTVAKPTVLYPKGTVATIGNPAGSNGSQFLIFFKDYAPTAAPTYSILGQVTGGLDTLAKIAKIPTVADSAGDKVTPKEKITIKSLTVAADTVAAAPSASVQS

Crispr_ID: NZ_LT827010_17

• CRISPR_ID: NZ_LT827010_17
• CRISPR_location: 7827902-7827982
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_17

Consensus_repeat	Method
GTGCTCTGACCGCGACCACCCACGGA	CRISPRCasFinder

spacers of NZ_LT827010_17

>17.1|7827928|29|NZ_LT827010|CRISPRCasFinder
AACTGGAGAGCTCCAGAACCACGAGGGTC

CRISPR arrays and Neighbor proteins around NZ_LT827010_17

CRISPR arrays

The CRISPR arrays of NZ_LT827010_17

>merge|NZ_LT827010|17|7827902-7827982|CRISPRCasFinder
GTGCTCTGACCGCGACCACCCACGGAAACTGGAGAGCTCCAGAACCACGAGGGTCGTGCACTGACCGCGACCACCCACGGA

>NZ_LT827010|17|15|7827902-7827982|CRISPRCasFinder
GTGCTCTGACCGCGACCACCCACGGA	AACTGGAGAGCTCCAGAACCACGAGGGTC
GTGCACTGACCGCGACCACCCACGGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014694037.1|7832526_7833759_-|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_LT827010.1|WP_014694042.1|7840404_7842327_-|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|235470
NZ_LT827010.1|WP_014694032.1|7825421_7826432_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_LT827010.1|WP_014694029.1|7822262_7823657_-|protoporphyrinogen-oxidase	unknown	unknown	gnl|CDD|237009
NZ_LT827010.1|WP_014694035.1|7829458_7831522_+|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl|CDD|236864
NZ_LT827010.1|WP_014694034.1|7828265_7829462_+|thiolase-family-protein	unknown	unknown	gnl|CDD|238383
NZ_LT827010.1|WP_014694040.1|7837631_7838981_-|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl|CDD|379140
NZ_LT827010.1|WP_043512791.1|7824839_7825412_+|DUF3000-domain-containing-protein	unknown	unknown	gnl|CDD|378665
NZ_LT827010.1|WP_014694039.1|7834879_7836589_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694043.1|7842476_7843880_+|C4-dicarboxylate-transporter-DctA	unknown	unknown	gnl|CDD|234968
NZ_LT827010.1|WP_014694038.1|7833755_7834418_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_LT827010.1|WP_014694028.1|7821564_7822266_-|chlorite-dismutase-family-protein	unknown	unknown	gnl|CDD|377705
NZ_LT827010.1|WP_043512793.1|7826577_7827879_+|ribonuclease-D	unknown	unknown	gnl|CDD|223426
NZ_LT827010.1|WP_014694024.1|7819301_7820099_-|thymidylate-synthase	unknown	unknown	gnl|CDD|376313
NZ_LT827010.1|WP_014694036.1|7831621_7832530_+|hypothetical-protein	unknown	unknown	gnl|CDD|370676
NZ_LT827010.1|WP_014694041.1|7839048_7840356_-|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl|CDD|379140
NZ_LT827010.1|WP_014694025.1|7820111_7820717_-|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl|CDD|179647
NZ_LT827010.1|WP_014694030.1|7823722_7824841_-|uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
NZ_LT827010.1|WP_014694026.1|7820785_7821040_-|isoamylase-early-set-domain-containing-protein	unknown	unknown	gnl|CDD|199892
NZ_LT827010.1|WP_014694027.1|7821122_7821578_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|225064

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014694037.1|7832526_7833759_-|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.03114e-44
NZ_LT827010.1|WP_014694042.1|7840404_7842327_-|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|235470	PRK05444, PRK05444, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional.	0
NZ_LT827010.1|WP_014694032.1|7825421_7826432_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.35382e-27
NZ_LT827010.1|WP_014694029.1|7822262_7823657_-|protoporphyrinogen-oxidase	gnl|CDD|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	5.5438e-118
NZ_LT827010.1|WP_014694035.1|7829458_7831522_+|enoyl-CoA-hydratase/isomerase-family-protein	gnl|CDD|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	3.29476e-120
NZ_LT827010.1|WP_014694034.1|7828265_7829462_+|thiolase-family-protein	gnl|CDD|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	4.71602e-146
NZ_LT827010.1|WP_014694040.1|7837631_7838981_-|PQQ-binding-like-beta-propeller-repeat-protein	gnl|CDD|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	5.49779e-06
NZ_LT827010.1|WP_043512791.1|7824839_7825412_+|DUF3000-domain-containing-protein	gnl|CDD|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	9.12399e-83
NZ_LT827010.1|WP_014694043.1|7842476_7843880_+|C4-dicarboxylate-transporter-DctA	gnl|CDD|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	2.65936e-158
NZ_LT827010.1|WP_014694038.1|7833755_7834418_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.87305e-76
NZ_LT827010.1|WP_014694028.1|7821564_7822266_-|chlorite-dismutase-family-protein	gnl|CDD|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	5.81328e-101
NZ_LT827010.1|WP_043512793.1|7826577_7827879_+|ribonuclease-D	gnl|CDD|223426	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis].	1.17129e-77
NZ_LT827010.1|WP_014694024.1|7819301_7820099_-|thymidylate-synthase	gnl|CDD|376313	pfam00303, Thymidylat_synt, Thymidylate synthase. This is a family of proteins that are flavin-dependent thymidylate synthases.	0
NZ_LT827010.1|WP_014694036.1|7831621_7832530_+|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	3.45709e-08
NZ_LT827010.1|WP_014694041.1|7839048_7840356_-|PQQ-binding-like-beta-propeller-repeat-protein	gnl|CDD|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	5.47351e-09
NZ_LT827010.1|WP_014694025.1|7820111_7820717_-|NAD(P)H:quinone-oxidoreductase	gnl|CDD|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	3.00241e-44
NZ_LT827010.1|WP_014694030.1|7823722_7824841_-|uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
NZ_LT827010.1|WP_014694026.1|7820785_7821040_-|isoamylase-early-set-domain-containing-protein	gnl|CDD|199892	cd07184, E_set_Isoamylase_like_N, N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins. E or "early" set domains are associated with the catalytic domain of isoamylase-like proteins at the N-terminal end. Isoamylase is one of the starch-debranching enzymes that catalyze the hydrolysis of alpha-1,6-glucosidic linkages specific in alpha-glucans such as amylopectin or glycogen. Isoamylase contains a bound calcium ion, but this is not in the same position as the conserved calcium ion that has been reported in other alpha-amylase family enzymes. The N-terminal domain of isoamylase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase. This domain is also a member of the CBM48 (Carbohydrate Binding Module 48) family whose members include pullulanase, maltooligosyl trehalose synthase, starch branching enzyme, glycogen branching enzyme, glycogen debranching enzyme, and the beta subunit of AMP-activated protein kinase.	1.05677e-22
NZ_LT827010.1|WP_014694027.1|7821122_7821578_+|GNAT-family-N-acetyltransferase	gnl|CDD|225064	COG2153, ElaA, Predicted acyltransferase [General function prediction only].	2.84213e-55

Protein sequences

>NZ_LT827010.1|WP_043512793.1|7826577_7827879_+|ribonuclease-D
MTDETPLRRRDAPESAGDGPHAVPPDPSSGGSEAVPLTAPRDGTPAPVESADGLAEVVARMAAGSGPVAVDAERASGYRYTQRAYLVQLRRAGSGTVLIDPLPLDDLRTLDTALADTEWVLHAASQDLPCLAELGMKPRRLFDTELAARLAGFERVGLAALTEHLLGYSLEKHHSAADWSTRPLPESWLTYAALDVELLTDLRDLLATELDKQGKAGWAAEEFASLVASADRPPRVRPDPWRRTSGIHRVRGARAQSRVRALWYARDAIAARKDSAPGRVLPDSAIVAAAEADPKDERTLLAIPGFGGRSVRRLVKTWLDALDQARALPDDALPVNQPVEGPPPPHRWAERDPIAAARLARCRQVVVGTAETYRLPPENLISPDFIRRLAWSPPDEVSAQTVSDTLRGFGARNWQVGLIAGQLAGVLPAPFTD
>NZ_LT827010.1|WP_014694032.1|7825421_7826432_-|trypsin-like-peptidase-domain-containing-protein
MTATYEPFTPEPRRHRAEESWGGQYQRWEPAAPEPRWPQEHPQWPEQARYEEPRPQWQEPPRFEEPRPQWQEPPRFEAPAPAYEAVPAKPTASKARPVVIGLVVLLLLVIGWQAYRIESVIKSSNDLAAAVSSEQNHSADLQKSLTGVFDPEGISTATLPSVYRVRAGDFTGTAFSVGTKAKSGTANLLTNFHVVESVYKAGTRTVQLEQGSTRISATIVKVSETKDLALLVAKKTIKPIKVATTKVKAGQQIVVLGNPLGLDDTVTTGVISAFRENDADGPTIQFDAPINPGNSGGPVVNANRQVVALATAKARDAEGIGLGIPIATVCALFDVC
>NZ_LT827010.1|WP_043512791.1|7824839_7825412_+|DUF3000-domain-containing-protein
MASPSAVPEAFTRAVTALRADSPRPEILLEEIAAPQRLAPYSFALSATVLRSGEEVASGRLILLHDPAGHDAWRGDLRLVTLVTAELEADLATDPLLPAVAWTWLTDALDQHAAACTAIGGTITQTASTRFGELAGPAPTADLEVRASWTPTSDDVTAHLYGWCAMLASTAGLPPPGVSSLSDRHRAPAT
>NZ_LT827010.1|WP_014694030.1|7823722_7824841_-|uroporphyrinogen-decarboxylase
MEEEYADLRPGRPRRAAGRRSLTWHDDPVTVLDDSPFVRACRGLPGPHTPVWFMRQAGRSLPEYRKLREGIGMLDSCRRPDLVTEITLQPVRRHRVDAAILYSDIVVPIAAAGVDLDIVPGTGPVVAEPIRTAADLQRLRPITADDVDYVAEAVRLLVAELGATPLIGFAGAPFTLASYLIEGGPSRTYLKTKAMMYAEPELWHALLARLAEITLAFLRIQIDAGVSAVQLFDSWAGALSEADYREFVMPHSARVLRGLDDAGVPRIHFGVGTGVLLEAMGEAGADVVGVDWRTPLDVASKRLGPDKAVQGNLDPAILFAGWDVVEREARRVLAQGQSAPGHVFNLGHGVMPEMDPDILTRLTALVHEASAR
>NZ_LT827010.1|WP_014694029.1|7822262_7823657_-|protoporphyrinogen-oxidase
MRKRIAVVGGGIAGLAAAVRLRDVTRADTEIIVYEQSGALGGKLRTGELAGLRVERGAESFLNGSPDGGPSAAVRFAHRVGLGDALVHPAAQPAALAIGGALARIPAGTLVGVPGDLSALDGVALPEADADADTGHPLLAAGQDIAVGELVRSRYGAEVVDRLVDPMLGGVYAGRADRLSLRATMPQLARTAETEHTLRGAVRAAQALSRRTPGQPVFAAVDGGMSRLIGAAATTARARISLGLPVRGITRTGNRWHLTLGPAPQPQTDEVDAVILAVPAAPAARLLADLAPGAAAALGDLEYASVALAGMALPPGTRLPELSGFLVPPGEGTLVKAATFFTRKWPHLTGPDGPVIVRASLGRAGEQERLQLSDPALLAIAHRELSELAGTRLPSPTASWIQRWGGGLPQYAPGHPDRVAAARAALPAGIALAGAALDGVGIPVCVASGEQAADDVNSYLEASA
>NZ_LT827010.1|WP_014694028.1|7821564_7822266_-|chlorite-dismutase-family-protein
MSEQTNAARINELNATIRYTMWSVFRASSPLPALRDELAGEVDTLFEQLAAKDVTIRGTYDVSGLRADADLMIWWHAADSDDLQEAYSLFRRTALGRHLTPVWSQMALHRPAEFNKSHLPAFLAGEEARPYLCVYPFVRSYEWYLLPDAERRELLAEHGRQARGYPDVRANTVASFALGDYEWMLAFEADELHRIVDLMRDLRASRARRHVREEVPFYTGRRRSISEIAASLP
>NZ_LT827010.1|WP_014694027.1|7821122_7821578_+|GNAT-family-N-acetyltransferase
MHPAPHDELRVASFRDLPAGTLYDILRLRSDVFVVEQNCAYPDLDGRDTEPGTRHLWFSRDREIRAYLRILDDHGTERIGRVVTAKTARGAGLAGRLMAHALEVVGHRPAVLDAQSYLVGFYRRYGFEPTGPEYVEDGIPHVPMARPATAG
>NZ_LT827010.1|WP_014694026.1|7820785_7821040_-|isoamylase-early-set-domain-containing-protein
MIKRSKLFGNKTRVTFSLPADEPSGVVSVVGTFNDWQPGRHELQVRRNGTRTVSVPLDPGEYEFRYLATGGVWFDDPEGSELRL
>NZ_LT827010.1|WP_014694025.1|7820111_7820717_-|NAD(P)H:quinone-oxidoreductase
MADVKLAIIYYSATGTLHRMAQRLQEAAEKAGADVRLRQVAELAPPEAIASNAAWSQHFDTTKDEPRAAADDVVWADAVLFGTPTRYGNVASQLKQFIDTLGPQWAQGQLANKAYAGFTASMTEHGGQESTLLALYNTIYHFGGVVVAPGYTDPLKFADGNPYGVSHVTGGSNDAPLTDVQYAALDHLARRIVQIGGRLRA
>NZ_LT827010.1|WP_014694024.1|7819301_7820099_-|thymidylate-synthase
MAVDTQYEDLLRRVLETGTRKSDRTGTGTRSLFGERLRYDLSQGFPLVTTKRVHFKSIAVELLWFLRGETNVQWLRDQGVTIWDEWASESGELGPVYGYQWRSWPTPDGHVDQISEILDTLRTDPDSRRMIVSAWNVGQLDEMALMPCHAMFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTRMVADQVGLTPGDFIWVGGDCHIYDNHVEQVREQLGRQAYPFPALEIAKRPSLFDYEYADFTVVGYEHHPAIKAPVAV
>NZ_LT827010.1|WP_014694034.1|7828265_7829462_+|thiolase-family-protein
MPREVREVVFVDGVRTPFGKAGGMYAETRADDLVIRCIRELIKRNPQLPTDRVDEVAIAATTQTGDQGLTIGRTAALLAGLPKTVPGYAVDRMCAGAMTAVTNVAGGIAMGAYDIAVAGGVEHMGRHPMGEGADPNPRILTEKLVDPSALVMGATAENLHDRLPHITKERTDLFALNSQLKVAKAYANGKLQPDLVPVAIRSSELGWGLATVDEAPRETSLEKLATLKTPFRPHGRITAGNAAGLNDGATAALLADEATARELGLPVAMRLVSYAYVGVEPEIMGYGPIPSTEKALKKAGLTIDDIGLFELNEAFAVQVLALLDHYGIADDDPRVNPWGGAIAVGHPLASSGVRLMTQLARHFEEHPEVRYGMNAMCIGIGMGGTVIWENPNWEGFKK
>NZ_LT827010.1|WP_014694035.1|7829458_7831522_+|enoyl-CoA-hydratase/isomerase-family-protein
MIENPNEVVTKALLRSVRVPGLDKPAALITLDNGFDHKKPNSFGPAGLQSLDEAITGALAADPAFIAVTGKPYIFCVGADITGMPLLSSREQAVELGELGHRVFARLRNSTIPTFAFVNGAALGGGLEVALHCHYRTVSSGATALGLPEVAIGLIPGWGGSQLLPNLIGIAGAAQVILQNPLTQKVLRPKQARELGVADALFEAADFLEDSLAWAAGVVKGEVTVERPEIDRDMWDGVLWFAKNQLDEKLHGAVPSANKALELLALAKEATFEDGTAAETEALADLIMGDEARASLYAFDLVQRRAKRPVGVPDKSLARKVTKVGIVGAGLMASQLALLFLRRLQVPVVLTDLDQERVDKGVAYVTGEIDKLVGKRRLDEGTAAKLRGLISGSVDKSVFADADFVIEAVFENLDLKKKIWAEFETIVKPEAILATNTSSLSITEMAAGLQHPERVVGFHFFNPVAVLPLLEIIRGEQTDDATLATAFAVGRELKKSSVLVKDAPAFVVNRVLTRFTSEVFKAVDAGTPLEVVNEAFDPMGLPMRPIALLQLVGPAVAYHVGETLHRAFPERYVDSPNLKRIVDAGLPLLVDDEINADVVKLLEVGDTVLTGDEVRAKALAALAEEIRIMLDEGVVAEAQDIDLCMILGAGYPFHLGGITPYLDRSGIAEQITGQRFLPNGLADVRRS
>NZ_LT827010.1|WP_014694036.1|7831621_7832530_+|hypothetical-protein
MSQDPYPGQPFPGVPNPNVPPQEGLPPTQPFPGAYPQPQQPAYGQQPPPYGQQQPAYGQQPPAYGQQQPAYGQPAYGQPQPSFPPIPPAPKKSKALPITLISIAIVLVLCVGGVVAINLLAKDDKSKGTATATSTSSTKATEGGAAKPAADITVVEPKTLGGRPKLTTAEFATITKTMQEGLKDGYPGATKSLGAFYGTPVKKNMVMTIAVAAPISDPELELDRNFTSMSTTGFSAEHITAVDTGSFGGSAKCGDGKVSSVPVAVCAWSDSGSVGMLVWYYTSKSAAEKQFPAIRAEIEKVG
>NZ_LT827010.1|WP_014694037.1|7832526_7833759_-|HAMP-domain-containing-histidine-kinase
MTVYQGQPVQHRESFLRRLARPTLRLRLTLLNGILLVAAGAVLVVLAWLLVDEPLHPADRLRVGSSVTLNDGTTREARSWQTETIDEASDQLLVKGLSALVAISIIGIAGGYLVTRRALRPLHQVTQTAQRLGEETLDQRIRYAGADDEVAELARTFDAMLDRLAGAFESQKRFVANASHELRTPLAVMRTEIDVTLSDPDADLAEYRRMARVVRDASSRANGLVDALLVLARSEAQSGRRLVRKVPADLATSVYNALSAVKEEAERMRLEVTTDLAAAPVVGDPSLLDRLAGNLIENAIRYNHLLGRLWLRTVSVDGQARLIVGNTGHEVEQAEVPGLFEPFRRGGWERTGSRGSGLGLSIVRAVCDAHGGTVSAIALADGGLEVTVSLPAADTTPVVAATASVPRGRS
>NZ_LT827010.1|WP_014694038.1|7833755_7834418_-|response-regulator-transcription-factor
MRVLVVEDERTMADAIARGLRRHGMAVDVAYDGAQGHEMAYVTRYDVVVLDRDLPGMSGDEICAALVDSGALTRVLMLTASASVADRVEGLQLGADDYLPKPFAFDELVARVQALGRRATPPAPPVFTVGNLVLDPGRRAVTRGETPVDLTNKEFGVLEVLLKASGAVVSSEELLERVWDANTDPFTTTVRVTVMTLRKKLGDPPLIDTVVGAGYRVVTT
>NZ_LT827010.1|WP_014694039.1|7834879_7836589_+|hypothetical-protein
MNLDTKPKRIAYALLVIAALVLGWMAIFDGPLEEMPGPAQATLRFFFGIVAALLAAALIFVAWPQRLGGGPGRPKPDNPGDNALDDEIQRSIAAVAAKYKDNQAKVLFSKLLLDNRLLVRAYDEIQLLDQSLACQTSIDYALDRTFTPSTQGSSLIPVPVIEARKGTLLDSFEVVSADDAVVPTLPQSETRGLLAHAIIACYSKAYNVSLDELLDRSKRPLALNALLRMVYRRGRASDQASEQEFRGIVSGVILTSTPAARRFGSRLEQLCTYYSRHYLVAVDVPVDAPTNRVHLQYRQTLPIYGLVANFRERVRVRCGLLPYKFKIPMPLIYRAASYHFSMRGTSGQYVANHEVVHTAKQEFLRAEDMEGRYAACYLRLRYRTGLPYARLYSRGFARIDAKSQDPLASIVEFAEVPPGALGGVARVAMVTTALVAVFAFLRPSVTEVSSDAAALLLAAPAAMAAWVGYSMERVRQSSLATYVGLAITQFVSVASAMLYILERRQQAWAEAHLTLHDQGVVGIWTLPDVDAGWLLLGLVGGVTAVSLIVLRTVRTRVYLREVAHWNDIA
>NZ_LT827010.1|WP_014694040.1|7837631_7838981_-|PQQ-binding-like-beta-propeller-repeat-protein
MALIDLDRVAPPGPPRAARPPIRAYRRGGLLLALVLLTVLGGAVPAAGICWRYLGAITSPLAPDGPIELAGGRVYTVGTAGADPVVTAWSTDDPPRRLWSVRAPVGAGPGVVPPSSVTVRPAGDVALLTAGVATTAVDAASGRIRWSSPIAVTVLAGSGIGVTVDRVFRAGTVYDQASGAPGPLYFSATGEPHTEPPLRTDVRGLDLADGHTVWTVAPGGAVTVDQVPGPDPAVLITSSARLSLVSGRTGEPVRQADLPRLSGHGPAGGALLGDVALVSYQNPGRQVAYRARTLQRLWSRPVPDLVADPADCQGVLCDGGHGNLRVLDPGTGQARWRTGEDVDLAIRAGYVLETDAASGEPVRLTDPHTGATAVDLDGWSAPVAGAADAPLLLRRRDGHGGQAFAAVVPGHAAVRELGSAGVRLGDCDADGHYLACRSPEGLRLWAYRI
>NZ_LT827010.1|WP_014694041.1|7839048_7840356_-|PQQ-binding-like-beta-propeller-repeat-protein
MGAETVIDLGLDRGVPESYERPRRATVPQWFAPVLLALLLLISSSASAAPPKPPFTPLLRIPMGPADPYLITAAGRLVTQTGDVVTAYDLTSGALSWRAGRSTPVLRLRTGDGMLLMQPWTIGGAAAGTTAISLATGERQWVNPRSVITFAGSDALIAVTGTRSLSGSGRRVQGLIEVLDTLTGDTRWRVRVPSTAVVLGVPGPSDAGARMLVVRDDRTAVLHDVADGRVLATRELPSANYGPDNPVVAGGTVLLRHPGVSGMEVSAYDPLTLRPLWTEEADGTLDVRPCGLLACLLGGGGVRAVDPATGDQRWAQRGWQAVEQRGTSLLAYREADGALPAALVDSATGRVLTDLTGWRPLAGANRAGRLLVIRAVPDGARTMVAVADPVGGRLRTIAGLPPGTGGCEAAPDRLVCRSAAGELVVWSYDETAGAR
>NZ_LT827010.1|WP_014694042.1|7840404_7842327_-|1-deoxy-D-xylulose-5-phosphate-synthase
MSDSPSTPAGLLASVTGPGALKRLSAEQLTLLAAEIRDFLVAKVSKTGGHLGPNLGVVEMTLAMHRVFDSPRDKILFDTGHQAYVHKIVTGRQDGFDLLRQRGGLTGYPSQAESEHDLIENSHASTALSYADGLAKAFALRGEDRHVVAVVGDGALTGGMCWEALNNIAATKNRLVIVVNDNGRSYAPTIGGLADHLSTLRLNPGYEKVLDLVKDALGSTPLVGKPVFEVLHAVKRGIKDAVSPQPMFEDLGLKYIGPVDGHDQQAMESALRRAKGFNAPVIVHAVTRKGYGYRPAEQDEADCLHGPGAFDPQTGALTAKPSLKWTKVFAEELVKIADERPDVVGITAAMAEPTGIAALAKKYPDRAYDVGIAEQHAATSAAGLAMGGLHPVVAVYATFLNRAFDQVLLDVAMHRLPVTFVLDRAGITGPDGPSHYGIWDMSVFGAVPGLRIAAPRDAATLREELREAVAVDDGPTIVRFPTGAVAADTPAVRRVGQVDVLREAEKKDILLVAVGSFVGLGLDAAERLAEQGYGVTVVDPRWVRPVPIELTGLAAQHRLVVTLEDGIRAGGVGDAVAAALRDAGVHVPLRDFGVPAGFHPHGTRAEILASLGLTAQDVARDVTGWVSGLDAGTSVAAPAI
>NZ_LT827010.1|WP_014694043.1|7842476_7843880_+|C4-dicarboxylate-transporter-DctA
MSVDAPAPRRRDRSHLLYLCVLLAMALGIAVGFAFPDFAVKLKPLGTGFVGLIRMMIAPVIFCTLVLGVGSIRRAAQVGRVGGLALGYFLIMSTVALTIGLIVGNILHPGAGLHLSQELAKTGTAQVSRTAEGGVDFVLGIIPDTLISALTSTQVLQTLLVALLVGFAVQSLGARGEPVIAAVALAQRVVFRILAMIMWLAPIGAFGAMAALVGATGFAALKSLAAIMVGFYVTCAIFVFLVLGLLLRLVAGVSIGRLLRYLAREFLLILSTSSSESALPRLIAKMGHLGVSRPVVGIVVPTGYSFNLDGTAIYLTMASLFIADALDRPLSIGQQIGLLLFMIVASKGAAGVTGAGLATLAGGLQSHRPDLVPGVGLIVGIDRLMSEARALTNFAGNAVATILIGTWTHEIDRDQAARVLSGEAPFDESTFDDDPHAGGTPPPAVDAASPASASAPPSPLAGPPTAL

Crispr_ID: NZ_LT827010_18

• CRISPR_ID: NZ_LT827010_18
• CRISPR_location: 7858451-7858556
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_18

Consensus_repeat	Method
GATGTCGTGCGCTCCGGCCGATAA	CRISPRCasFinder

spacers of NZ_LT827010_18

>18.1|7858475|58|NZ_LT827010|CRISPRCasFinder
TCGATCACCACTCCCGGGCAGCTTCCCTCCAGAAGACCCAGAGCAAGATCAACATCAT

CRISPR arrays and Neighbor proteins around NZ_LT827010_18

CRISPR arrays

The CRISPR arrays of NZ_LT827010_18

>merge|NZ_LT827010|18|7858451-7858556|CRISPRCasFinder
GATGTCGTGCGCTCCGGCCGATAATCGATCACCACTCCCGGGCAGCTTCCCTCCAGAAGACCCAGAGCAAGATCAACATCATGATGTCGTGCGCTGCGGCCGATAA

>NZ_LT827010|18|16|7858451-7858556|CRISPRCasFinder
GATGTCGTGCGCTCCGGCCGATAA	TCGATCACCACTCCCGGGCAGCTTCCCTCCAGAAGACCCAGAGCAAGATCAACATCAT
GATGTCGTGCGCTGCGGCCGATAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_172898816.1|7866314_7866890_-|Fe-S-cluster-assembly-protein-HesB	unknown	unknown	gnl|CDD|132296
NZ_LT827010.1|WP_014694068.1|7866939_7867440_-|GAF-domain-containing-protein	unknown	unknown	gnl|CDD|225113
NZ_LT827010.1|WP_014694062.1|7862626_7863241_-|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl|CDD|225415
NZ_LT827010.1|WP_099344224.1|7864726_7865614_+|ribokinase	unknown	unknown	gnl|CDD|238571
NZ_LT827010.1|WP_014694053.1|7852678_7853191_+|DUF3093-domain-containing-protein	unknown	unknown	gnl|CDD|378627
NZ_LT827010.1|WP_014694059.1|7858098_7858341_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694069.1|7867436_7867709_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694061.1|7860802_7862533_-|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|223989
NZ_LT827010.1|WP_043516167.1|7855230_7856043_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238817
NZ_LT827010.1|WP_014694066.1|7865841_7866213_-|DUF3099-domain-containing-protein	unknown	unknown	gnl|CDD|378630
NZ_LT827010.1|WP_014694052.1|7852108_7852585_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NZ_LT827010.1|WP_014694056.1|7854673_7855222_+|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|379163
NZ_LT827010.1|WP_043516169.1|7856306_7857854_+|RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|235640
NZ_LT827010.1|WP_043516174.1|7863590_7864541_+|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl|CDD|377251
NZ_LT827010.1|WP_014694055.1|7854031_7854328_-|DUF4193-domain-containing-protein	unknown	unknown	gnl|CDD|379391
NZ_LT827010.1|WP_014694050.1|7851071_7851449_-|OB-fold-nucleic-acid-binding-domain-containing-protein	unknown	unknown	gnl|CDD|239934
NZ_LT827010.1|WP_014694054.1|7853141_7853906_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694051.1|7851474_7852122_-|DUF3710-domain-containing-protein	unknown	unknown	gnl|CDD|378867
NZ_LT827010.1|WP_043512800.1|7863248_7863473_-|DUF3039-domain-containing-protein	unknown	unknown	gnl|CDD|378609
NZ_LT827010.1|WP_014694060.1|7859173_7860751_-|GGDEF-domain-containing-protein	unknown	unknown	gnl|CDD|143635

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_172898816.1|7866314_7866890_-|Fe-S-cluster-assembly-protein-HesB	gnl|CDD|132296	TIGR03252, TIGR03252, uncharacterized HhH-GPD family protein. This model describes a small, well-conserved bacterial protein family. Its sequence largely consists of a domain, HhH-GPD, found in a variety of related base excision DNA repair enzymes (see pfam00730). [DNA metabolism, DNA replication, recombination, and repair].	5.36118e-69
NZ_LT827010.1|WP_014694068.1|7866939_7867440_-|GAF-domain-containing-protein	gnl|CDD|225113	COG2203, FhlA, FOG: GAF domain [Signal transduction mechanisms].	3.32083e-07
NZ_LT827010.1|WP_099344224.1|7864726_7865614_+|ribokinase	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	2.08413e-50
NZ_LT827010.1|WP_014694062.1|7862626_7863241_-|trimeric-intracellular-cation-channel-family-protein	gnl|CDD|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	1.92055e-45
NZ_LT827010.1|WP_014694061.1|7860802_7862533_-|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	2.99712e-56
NZ_LT827010.1|WP_043516167.1|7855230_7856043_-|inositol-monophosphatase	gnl|CDD|238817	cd01639, IMPase, IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be recycled into inositol lipids; in eukaryotes IMPase plays a vital role in intracellular signaling. IMPase is one of the proposed targets of Li+ therapy in manic-depressive illness. This family contains some bacterial members of the inositol monophosphatase family classified as SuhB-like. E. coli SuhB has been suggested to participate in posstranscriptional control of gene expression, and its inositol monophosphatase activity doesn't appear to be sufficient for its cellular function. It has been proposed, that SuhB plays a role in the biosynthesis of phosphatidylinositol in mycobacteria.	1.94928e-88
NZ_LT827010.1|WP_014694066.1|7865841_7866213_-|DUF3099-domain-containing-protein	gnl|CDD|378630	pfam11298, DUF3099, Protein of unknown function (DUF3099). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	3.40487e-25
NZ_LT827010.1|WP_014694052.1|7852108_7852585_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	9.25766e-70
NZ_LT827010.1|WP_014694056.1|7854673_7855222_+|LytR-C-terminal-domain-containing-protein	gnl|CDD|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	1.59682e-11
NZ_LT827010.1|WP_043516169.1|7856306_7857854_+|RNA-polymerase-sigma-factor	gnl|CDD|235640	PRK05901, PRK05901, RNA polymerase sigma factor; Provisional.	0
NZ_LT827010.1|WP_043516174.1|7863590_7864541_+|pseudouridine-5'-phosphate-glycosidase	gnl|CDD|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	7.39009e-149
NZ_LT827010.1|WP_014694055.1|7854031_7854328_-|DUF4193-domain-containing-protein	gnl|CDD|379391	pfam13834, DUF4193, Domain of unknown function (DUF4193). This domain of unknown function contains four conserved cysteines and a conserved histidine, including a CXXXXH motif.	1.76833e-52
NZ_LT827010.1|WP_014694050.1|7851071_7851449_-|OB-fold-nucleic-acid-binding-domain-containing-protein	gnl|CDD|239934	cd04488, RecG_wedge_OBF, RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a four-stranded (Holliday) junction in vivo and in vitro. This interconversion provides a route to repair stalled forks. The RecG monomer contains three domains. The N-terminal domain is named for its wedge structure, and may provide the specificity of RecG for binding branched-DNA structures. During the reversal of fork to Holliday junction, the wedge domain is fixed at the junction of the fork where the leading and lagging strand duplex arms meet, and is thought to promote the unwinding of the nascent leading and lagging strands. In order to form the Holliday junction, these nascent strands would be annealed, and the parental strands reannealed. The wedge domain may also be a processivity factor of RecG on these branched chain substrates.	6.59623e-10
NZ_LT827010.1|WP_014694060.1|7859173_7860751_-|GGDEF-domain-containing-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	6.35853e-49
NZ_LT827010.1|WP_014694051.1|7851474_7852122_-|DUF3710-domain-containing-protein	gnl|CDD|378867	pfam12502, DUF3710, Protein of unknown function (DUF3710). This family of proteins is found in bacteria. Proteins in this family are typically between 237 and 284 amino acids in length. There are two conserved sequence motifs: DLG and DGPRW.	1.87887e-65
NZ_LT827010.1|WP_043512800.1|7863248_7863473_-|DUF3039-domain-containing-protein	gnl|CDD|378609	pfam11238, DUF3039, Protein of unknown function (DUF3039). This family of proteins with unknown function appears to be restricted to Actinobacteria.	3.29289e-26
NZ_LT827010.1|WP_014694053.1|7852678_7853191_+|DUF3093-domain-containing-protein	gnl|CDD|378627	pfam11292, DUF3093, Protein of unknown function (DUF3093). This family of proteins with unknown function appears to be restricted to Actinobacteria. Some members are annotated as alanine rich membrane proteins however this cannot be confirmed.	7.86621e-44

Protein sequences

>NZ_LT827010.1|WP_014694059.1|7858098_7858341_+|hypothetical-protein
MTPTLTPPAGSLAGTAADERCDRCNAAGKLRLTLAGGGDLVFCGHHANRYAEDLVKIAVQFSADPEFTWRGANMMSNSSN
>NZ_LT827010.1|WP_043516169.1|7856306_7857854_+|RNA-polymerase-sigma-factor
MTEAHQNGADVRSLTEALITHAQGAGGQLTSAQVAHTLESAAVNPAQAKKILRGLVDAGITVVVDGSASTRRKVAAARSATPASKATTAKTAAPVKKAAPAPKQAAAPSTDPAKATPAARKAAPAKKAAVTAKAAPAKAAKPGEEGPEGEEIDPEELAAEIEDVVVEEPPALVAAAATDAASSATDGDFEWDDEESEALKQARRDAELTASADSVRAYLKQIGKVPLLNAEQEVELAKRIEAGLYAAERLRAAEEGEETLERNFERDLKWINRDGERAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMDITPEKVLEIQQYAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFSLLQDQLQQVLQTLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD
>NZ_LT827010.1|WP_043516167.1|7855230_7856043_-|inositol-monophosphatase
MSPGSTPGELLEIAVRVAREAAATASRMRGEAIGDVQTKSTDTDVVTAADRAVERQVVAALRAERPGDTVLGEEYGGAAGAAPGAVRWILDPIDGTVNYLYGLPQYAVSLAAEVDGEVVAGVVRNAATGDEWTATRGGGAWRDGRRISCSTETVLGQALVGTGFGYDPRRRAHQGRVFAQMITRVRDIRRLGAASLDLCLAAEGRLDAFFEKGLNTWDHAAGGLIAAEAGMVVSGLGGAPAGPEMVLLAPPALHPALHDLLVEVDAAGGP
>NZ_LT827010.1|WP_014694056.1|7854673_7855222_+|LytR-C-terminal-domain-containing-protein
MSFARVRALVVVGVLAVAAIVFVIVALVRDDQADIAAGGKCAAGAPAADIHLPDDPAEVTLQILNGTNRAGLADSVSTEFKNRRFTVKDPGKSKSKLKGVAEIRFGPDTVGKAQLVKAYFLAQAKMVYSDKRKGELIEVVIGSDFQQLATTTEVNQSLVEIGEPTLPPGACLKPVTKKPEND
>NZ_LT827010.1|WP_014694055.1|7854031_7854328_-|DUF4193-domain-containing-protein
MATDYDAPRRDEVDLGEDSLEELKSRRADSQSGAVDVDEVEVAESFELPGADLADEELTVKVLPMQTDEFRCSRCFLVHHRSQLATERNGELICRECA
>NZ_LT827010.1|WP_014694054.1|7853141_7853906_-|hypothetical-protein
MDATGDDEELGRTVAALTADDLESSGRRRLLGRLVGDVRRRGVGRLFKPRAALRWMAEVVTDVAPHIPVRDRETLRRHFPGLDDDDLADRLIRNAARATAGVGAAGGGVAAVEWVAAPVLLSAPVLLSAETIAVVAIEMKLIGELHELYREPIPGNGTERALALIQSWAGQRGVNPLVPGTGVASVLGTAARGELQKTLLRRFGRNLTSMGPMLTGAAVASYLNRRATRSIGDKVRDDLRKRALTRPDRPALDD
>NZ_LT827010.1|WP_014694053.1|7852678_7853191_+|DUF3093-domain-containing-protein
MTPESPARSTPAYQERLGLPWWVWPAGLLIGAILGTEVALALPGLPGWLPYAVLVPLAVLLPLPLGRLRVAVREGEFLVDDARLPVAVIADVVALDAAGKREALGVGAHPLAFVVQRPWIGGAVQVLLDDPADPTPYWVVSTRRPVELATALLAVSRPARAGQASSEPAS
>NZ_LT827010.1|WP_014694052.1|7852108_7852585_-|dUTP-diphosphatase
MSDVVIPVRLIDPDLPLPAYAHPGDAGADLVAAQDVEIAPGEWAKIGTGIAVAIPEGFVGLVHPRSGLAARLGVTVLNAPGTVDAGYRGEILVNLINHDRARAVKISRGDRIAQLVVQRVERAAFHVVDSLDDTARGTGGHGSTGGFSEGKAGSDVLP
>NZ_LT827010.1|WP_014694051.1|7851474_7852122_-|DUF3710-domain-containing-protein
MFSRKREGAKHVRAADAPPSKALAQSLAADGEAPAPEFGPWDVKHAPGDVQRLDLGSLQIPAIEGVEVRVQANPEGGVEQIVLVDGESALQLGVFAAPRTEGIWDEVREEIAGAMTADGVAAREVTGRYGTELLARVNTPEGPADVRFVGVDGPRWMVRALFQGAAAADPGREGVLGVALEGLVVVRDDEPRPVREPLPLRLPREMAEQNPAQQV
>NZ_LT827010.1|WP_014694050.1|7851071_7851449_-|OB-fold-nucleic-acid-binding-domain-containing-protein
MTTEQRTGLRRFLDRLTATDSELDAEELQRDAVKCGAMPAGQCRRGQVVSVSGRLRTVAYTPRTNLPTLEADLWDGSDVVTLVFLGRRSIAGIEPGRQLTARGRIAIRDDRKVIYNPYYELEAPR
>NZ_LT827010.1|WP_014694060.1|7859173_7860751_-|GGDEF-domain-containing-protein
MRETTQHAVRLLERAQTGDATAALAEAETVLRSPGGDLACMHFVRVVCRIAQSDPAGAIAAVGPMLCAAEREGSRGWQAAGLASRAWQRLRAASTGGMTADHDTDEVLRDLVAAEMLADGEPDPVAAVNSRVAVAIGWYELRLYELAEPQFTVAYRMSSADAGRNGNRAMWSLNLAEMHLRWALELYQIHRPAEAEGHSAEAERYAIRAAGEVSGADAACWRDNALLYAACARADRHDPGGAAADIVRYTARLRDRGFPTDALAISRPFHGVALLRSGRPADALAVMAEAATGLPPDADWLVVASTHRTRAVLLAHLGSADAAATLAYGDGLAAALWRQRLNTLHAARTRYDLEQLRVQHEQVAKAAEIDPLTGIANRRAFDQALHAALSRPGDAAVLLIDTDKFKVINDTLGHAAGDAALRAIAAALAAQVEAADLVARLGGDEFAALLPGAGAAEAAAVARRMVQAVRDIPDCLATVSIGIAVGPAAALHDVLEQADEAMYRAKHRGGDGTETTFTPQNRAAA
>NZ_LT827010.1|WP_014694061.1|7860802_7862533_-|DEAD/DEAH-box-helicase-family-protein
MSPSLPNLEIFPPLRAWQRKAMVEYLRRRSEDFMAVATPGAGKTTFALRLAAEMLVDGTVDAVTVVCPTEHLKSQWAQAAARVGIQLDPRFRNSEIHSSRDFHGAVVTYAQVGMAPQVHKRRTITRRTFVILDEIHHAGDSRSWGDGVKDAFEPAARRLLLTGTPFRSDENPIPFVQYERGMDGIQRSKADSVYGYGDALRDRVVRPVMFMAYSGETRWRTNAGDELAAKLGEPMTKDLIAQAWRTALDHRGEWMPQVMQAAHNRLLRVREGMPDAGGLVIASDQTAARAYAKLLHDLTGEAPTVVLSDDDGASGRIAEFAASQKLWMVAVRMVSEGVDIPRLAVGVYATSASTPLYFAQAIGRFVRSRQPGETATVFLPSVPHLLGLASEMEAERNHVLGAPKEKDGLDDELLERAQKSEDAIGDLEKQFEALSATAELQEVIYDGTSFGVPARTGTAEEADYLGLPGLLTPDEVTMLLNKRQTEQLAVQKRHEQEAARNAPEPAPREAVVPMSAGERRATLRRQLNTLVAAHHHRTNLPHGKIHAELRRLCGGPPSAQATIEQLEERIATIQTF
>NZ_LT827010.1|WP_014694062.1|7862626_7863241_-|trimeric-intracellular-cation-channel-family-protein
MASGYGLLVADLIGVAVFAASGASAGVAKRLDLFGVAFVGFASALGGGILRDLTIGAVPPLAFADWRYAVTAVLASVAVFWLHPRLHRVRRTVLVLDAAGLGLFTATGTLKALTAGVPPVGACLLGMLTAIGGGLTRDLLTGEIPVVLQRDIYASVALGGAILVTGMQRLGHTGPVPLAGAAALMTGVRLLALYRRWSAPVAVP
>NZ_LT827010.1|WP_043512800.1|7863248_7863473_-|DUF3039-domain-containing-protein
MPVSTQILERPETKDADTGPEMFHYVRKEKIAESAVMGTYVVALCGETFPVTKVPKKGSPVCPQCKEIYEAMKA
>NZ_LT827010.1|WP_043516174.1|7863590_7864541_+|pseudouridine-5'-phosphate-glycosidase
MTDFAIRFGEHVIRARRDGRPVVALESTIISHGLPHPDNLRVAREIEQTVRDNGAVPATIGMIGGELIAGLDDAQIEHLALAGDVAKLSVRDLAIAAAHRADGATTVAATSAVAAAAGIGVFATGGLGGVHREANLTFDESADLTALARTPIVVVCAGVKSILDVGATLERLETLGVSVAGYGTRRFPGFFITDGGFDVDWQLDSPEQVADFIRARRDQDVTTGALVLANPLPTDEQLDPELHDRTLASGLAALAEQGVTGKAVTPFLLAHFHSSTDGQSLTTNVRIILRNAALAARIAVAESAGTAAPLGFSVPA
>NZ_LT827010.1|WP_099344224.1|7864726_7865614_+|ribokinase
MIVVGDLVTDVLVEHDGPIRPGSDTAAAIRVSGGGQAANTAAWLARAGQATTLVAAVGADQAGRDRVAELVAAGVGDAVRVLPGAATGSVVVLTGASERTMITDRGACLLLDPAHVTAALRAAAPGDHLHLSGYPLLHAGSRPAGLAALAAARQQGLTVSVDAASAAPLRDAGASAFLTWVRDADLLLCNADEADVLAGPAPAAAQATRLTATVRHAVVKQGPAGAVWATRDGSAWSAPGLSVPVKDPTGAGDAFAAGLLTSWLNDGSPPAALQAGAALGAAAVQLLGARPDPSR
>NZ_LT827010.1|WP_014694066.1|7865841_7866213_-|DUF3099-domain-containing-protein
MKKQPSVLITDAARSPGDQLRSREVRYVLMMGTRVGCLILGGVLVSVRPPLLALWLVLCLAGMVFLPWAAVLIANDRPPKTKAERAADAAARERQQMALTEVVPEEREPVTIDSEIIESDKKL
>NZ_LT827010.1|WP_172898816.1|7866314_7866890_-|Fe-S-cluster-assembly-protein-HesB
MTFSLPIPAEANALLDRSPLAVLLGLVLDQQITMEKAFTSPLVLAQRLGHEPTATEIADFDPEALVEIFATPPALHRFPKAMAARAQEVCRVIADRYAGDVEALWRDASSGAELYQRIFALPGFGKQKAQIFVALLGKQVGVQPSGWRAAAGGYGEEGAYRSVADIVDDESLARVRENKKAAKAEARAAKG
>NZ_LT827010.1|WP_014694068.1|7866939_7867440_-|GAF-domain-containing-protein
MTARHPDRIRDLARLGLDREEHRGYLGELVKTVADRLQTPFALADALLNDAQVFLAGTGPVPDWIGESGGTPLEWAFCTRFLTTSAPFTVGDFTEDPEHRDNPLVRIEGVRSYVGAPLISSTGHVLGGLCALDVRPRHFTEDDMRYLSGMAAETVRRIEDHAGRAA
>NZ_LT827010.1|WP_014694069.1|7867436_7867709_-|hypothetical-protein
MARIEDYGHEAPTEQDAVKAFAELVGPRMAEGLWSLAVQSLGLQRPVSSPADLRRVAEHVMEVGELSRVAGRSLKVRLITYEALARTVQS

Crispr_ID: NZ_LT827010_19

• CRISPR_ID: NZ_LT827010_19
• CRISPR_location: 7917560-7917662
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_19

Consensus_repeat	Method
ACCGGCGGCTTCGGATGCCGGCGC	CRISPRCasFinder

spacers of NZ_LT827010_19

>19.1|7917584|55|NZ_LT827010|CRISPRCasFinder
TTCCGCGGTCGGCGCCTCGATGACCAGCCCGCTTCAGCAACCAGCCCTCTCAGCG

CRISPR arrays and Neighbor proteins around NZ_LT827010_19

CRISPR arrays

The CRISPR arrays of NZ_LT827010_19

>merge|NZ_LT827010|19|7917560-7917662|CRISPRCasFinder
ACCGGCGGCTTCGGATGCCGGCGCTTCCGCGGTCGGCGCCTCGATGACCAGCCCGCTTCAGCAACCAGCCCTCTCAGCGACCGGCGGCTTCAGATGCCGGCGC

>NZ_LT827010|19|17|7917560-7917662|CRISPRCasFinder
ACCGGCGGCTTCGGATGCCGGCGC	TTCCGCGGTCGGCGCCTCGATGACCAGCCCGCTTCAGCAACCAGCCCTCTCAGCG
ACCGGCGGCTTCAGATGCCGGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA	unknown	unknown	gnl|CDD|236476
NZ_LT827010.1|WP_043512810.1|7909911_7911414_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl|CDD|237674
NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein	unknown	unknown	gnl|CDD|378612
NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_LT827010.1|WP_043512820.1|7929414_7934382_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|137505
NZ_LT827010.1|WP_099343936.1|7909220_7909718_-|SigE-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|132028
NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE	unknown	unknown	gnl|CDD|236807
NZ_LT827010.1|WP_014694105.1|7907532_7908483_+|LysR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|176115
NZ_LT827010.1|WP_172898818.1|7911437_7911881_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein	unknown	unknown	gnl|CDD|274850
NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX	unknown	unknown	gnl|CDD|234646
NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|185378
NZ_LT827010.1|WP_014694112.1|7913744_7914455_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_014694106.1|7908495_7909218_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694110.1|7912015_7912759_+|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224051
NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274648
NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|378988
NZ_LT827010.1|WP_014694111.1|7912821_7913703_+|glutamate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270408
NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y	unknown	unknown	gnl|CDD|237177

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_043512810.1|7909911_7911414_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl|CDD|237674	PRK14326, PRK14326, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein	gnl|CDD|378612	pfam11248, DUF3046, Protein of unknown function (DUF3046). This family of proteins with unknown function appears to be restricted to Actinobacteria.	4.65091e-24
NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.06035e-45
NZ_LT827010.1|WP_043512820.1|7929414_7934382_+|DEAD/DEAH-box-helicase	gnl|CDD|137505	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional.	0
NZ_LT827010.1|WP_014694110.1|7912015_7912759_+|amino-acid-ABC-transporter-ATP-binding-protein	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	8.81629e-157
NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE	gnl|CDD|236807	PRK10958, PRK10958, leucine export protein LeuE; Provisional.	2.95095e-106
NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA	gnl|CDD|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_LT827010.1|WP_014694105.1|7907532_7908483_+|LysR-family-transcriptional-regulator	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.83563e-48
NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein	gnl|CDD|274850	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain. This model represents a clade within the uracil-DNA glycosylase superfamily. Among characterized proteins, it most closely resembles the Thermus thermophilus uracil-DNA glycosylase TTUDGA, which acts uracil (deamidated cytosine) in both single-stranded DNA and U/G pairs of double-stranded DNA. This domain may occur either as a stand-alone protein or as the C-terminal domain of a fusion with another domain that always pairs with a particular radical-SAM family protein.	2.57656e-78
NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX	gnl|CDD|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	2.75018e-34
NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	2.90805e-94
NZ_LT827010.1|WP_014694112.1|7913744_7914455_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.19357e-51
NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.12818e-101
NZ_LT827010.1|WP_099343936.1|7909220_7909718_-|SigE-family-RNA-polymerase-sigma-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	6.32421e-32
NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|274648	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity].	8.6841e-103
NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	1.46684e-43
NZ_LT827010.1|WP_014694111.1|7912821_7913703_+|glutamate-ABC-transporter-substrate-binding-protein	gnl|CDD|270408	cd13690, PBP2_GluB, Substrate binding domain of ABC glutamate transporter; the type 2 periplasmic binding protein fold. This group includes periplasmic glutamate-binding domain GluB from Corynebacterium efficiens and its related proteins. The GluB domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.50912e-81
NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0

Protein sequences

>NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y
MAPQYWVLVVAIVVLAVSVIVGLTLGARALGQLRTERQDAHDRQEQEVGVAQAKVADANAKAASVRAEAAAAKAEAAAARAEARRVLENAHSEADTILEHAHRQAEADVEQLRTAARRSGEREIALLNATVKEQAAEVERRAARIDERERLHGEEVERLVERERRLVALESELAKREATLKARETEVEAAENTKRRELERIAGLTTETAKGELIDAIEGQAKREAAILIRDIEQDARSTADTRARHIVVDAIQRIASEQTAESVVSVLHLPSDEMKGRIIGREGRNIRAFESTTGVNLIIDDTPEAVLLSCFDPVRREVGRLTLEKLVLDGRIHPHRIEEVFDSAKNEVERLCDRAAEEALVDVGITNIHPELVKLLGRLRYRTSYGQNVLKHLVETAHIAGIMAAELGLDVPIMKRAAFLHDIGKALTHEVEGSHALIGADVARKYGEHEEIVHAIEAHHNEVPPQTIEAVLTQASDACSGGRPGARRESLEAYVKRLERIEEIAGGKLGVEKVFAMQAGREIRVMVRPDDIDDIGAAVLARDVAKQIEEELTYPGQIRVTVVRESRVTELAR
>NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease
MSQQSVLYDVPGPRQRRITLISSLLVAIGLLAGIYYLIYLPLHHKGQFSMKLWGPLIDPGNEDFSAVWDRIGVGVKNTLTAAVFAIIGSLIIGTLLSVLRIELESLARRRFPGIAAPVALLLRALSVALAWATRICIEVFRGLPVVLTIFFVARGLPEFGVSMDTLWYLVIGLTIYNSVVIGEILRSGMTGLPPGQREAAAAIGLSSPQTTMIVLLPQAFRIMLPALISQLVVVLKDTSLGFIISYEETLNIGKQIIGVLSNPIQVYAVIGTLFILVNYSLSKLAQYVQRRLSRGRKTAGMPRRQPPTAALIAQAEGAGGTA
>NZ_LT827010.1|WP_014694112.1|7913744_7914455_+|amino-acid-ABC-transporter-permease
MSVIFDRFDVFAGGFWLTLQICVLAAIGALFLGAVVAVLRISPVPPLRALGTAYVTVFRNMPLTVVMFFAAFALPALGSNADFLRIPVLDAIFTRLGTDLPYFRFALIALVLYTAAFVCEALRSGVNAVQPGQSEAARSLGMTFGQNLRYVVLPQSWKASIVPLGSVIIAMIKNSALIGFFGVVGDLSQTADQLTSAEGLAFVPVAIGVSIGYLIMTVPLGALLDRIERRQAVTAR
>NZ_LT827010.1|WP_014694111.1|7912821_7913703_+|glutamate-ABC-transporter-substrate-binding-protein
MRLQRLAAVATATALVFGLAACGDKSDGGSKSGAGSKSFPAGSTMERLNKAQTIKVGTKFDQPGFGLKGLSGKPEGFDVEISKIIVKELGIPADKIQYVETPSKVREDSIVNNTVDFVVATYTINDERKKRVAFAGPYYEAGQNILVKADDSTITGPDSFKDGTKKVCSVTGSTPAEKIKTYVKDVPSQVVLFDTYDKCIAALDGGQVNAVTTDNVILLGYISKNQGKYKLAGPNFTKEPYGIGVKLEDKDFRTFINDTLEKSFADGSWKKAWDDTAGKFGAELGAAPTVNRY
>NZ_LT827010.1|WP_014694110.1|7912015_7912759_+|amino-acid-ABC-transporter-ATP-binding-protein
MAGEALIVLENVNKWFGPLHVLKDVDLSVERGEVVVVIGPSGSGKSTLCRAINRLEPIDSGSITFDGQPLPAEGRALARLRSEVGMVFQSFNLFAHKTIVQNVMLGPVKVRKEKPAAARERAMALLDRVGIAAQADKFPAQLSGGQQQRVAIARALAMQPKALLFDEPTSALDPEMVGEVLDVMTALAREGMTMVVVTHEMGFARHAANRVVFMADGQLVEQATPAEFFANPKSERARDFLSKILTH
>NZ_LT827010.1|WP_172898818.1|7911437_7911881_-|hypothetical-protein
MAGLWNWSAAGLIEPERVRNALAGALETPVGEIAGGGFGGLLCDVYQVGGDFPTLIDVFLAPGHLAEETIASAVAVRLGAALLLPDDTLNPTRYVLAEPDGTLRAVHVEEEETDDGVERRHARPCTGADPDCATGPGCARSRFRAAA
>NZ_LT827010.1|WP_043512810.1|7909911_7911414_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MTTEMQSSSGMPSAARTYDVRTYGCQMNVHDSERISGLMEDAGYVRAADADAADVVVFNTCAVRENADNRLYGNLGHLRPTKLKNPGMQIAVGGCLAQKDQGDIVKKAPWVDVVFGTHNIGSLPALLERARHNEQAQVEILESLEVFPSTLPTKRESTYAGWVSISVGCNNTCTFCIVPSLRGKEKDRRPGDVLAEVRALVAEGVLEVTLLGQNVNSYGVEFGDKLAFGKLLRACGDVEGLERVRFTSPHPKDFTDDVIAAMAETPNVCHSLHMPLQSGSDRVLKAMRRSYRQEKYLDIIDKVRAAMPDAAITTDIIVGFPGETDEDFEQTLEVVRRARFSSAFTFQYSKRPGTPAATMAEQVPKKVVQERYERLIATLEEITWAENGKLVGETVEVLVAVGEGRKDERTGRMSGRARDGRLVHFATGDLSPRPGDIVETVITYAAPHHLNADGAPLSHRRTRAGDAAEAGTTPKLKGVSLGLPTIGVPAPLPAAEGCAL
>NZ_LT827010.1|WP_099343936.1|7909220_7909718_-|SigE-family-RNA-polymerase-sigma-factor
MAEQRGRMVYTARLLTAGDAFLAEDLVQTALTKLYVSWAAFGRADSPDAYVRRALFNALVDERKRIWRRHERPVADVPDRAGELVGADDGDPELARALGELPPRMRAAVVFRFVHDMDVAETARALGCSAGTVKSQTARALDKLRAALGQPALATTFSGQPQGAS
>NZ_LT827010.1|WP_014694106.1|7908495_7909218_-|hypothetical-protein
MDLHTRLERFGGPIEAAAADTIAADVERGQRALRRRRTFRTSAVTAFGMAAIVATISVTGAVTGTAPSGPAVAASLPAAAGSTPAARVKLVDYTGAQPKWFTIDKVPEGYFVQKDDEGGLTIAPASVKNPPPGADPSKDPRYDPSVLTDKIGIYLEPTWYREGNDDGEKVTVGGFPAVLHGAAPLQQLMILVSPKVYATVQADVPLTRDQLLELGAGLHVSKEAVDRMAASTGKTGKTGK
>NZ_LT827010.1|WP_014694105.1|7907532_7908483_+|LysR-family-transcriptional-regulator
MLDVTRLRVLVAVARCGSVTAAAQALHYAQPSVSHHLARLEAETGSRLIQRAGRGIRLTDAGRMLAERAEEILGRLDAAEAELAAHTGLRSGRVRLAAFPSALGTFVPAAAAGFVGAHPGIDLRFTEAEPPAAVRLLRSGEVEVALLFTYPGETVPDLDGLRPEPLLEERLYLVTPGDRAGDTLADHRDRPWISGCERCRAELLRVCAAAGFTPDIRFTTDDYVAVQALVAAGLGVTVLPALALAAHQDPGVRTVALPDTARTVYAAVYGDTPDPPGTTALLGHLRAAAGLPAYASIGNLNRPRTASGPRPGRSGW
>NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX
MGGPEGEGSDGRFALRAGARGGGGAGERKPAGPAQSESERAREICLRQLAVRPRTRAELAKVLARKEISEEVIAEVLDRYDEVGIINDAAFARAWVSSRHHGRGLARRALANELRQRGVDAEVAGEALESVDDESEAETARALVDRKLRTASGTPEAVFRRLVAMLARKGYPVGIAIRAVKEALAARDAEAAEFADAVDADALADQAEDPHS
>NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA
MVAAPDREKALELALAQIDKQFGKGSVMRLGERPVVQTAVIPTSSIALDVALGVGGLPRGRVIEVYGPESSGKTTVALHAVANAQKAGGTAAFIDAEHALDPDYARALGVDTDALLVSQPDTGEQALEIADMLIRSGALDIIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITGVLNNTGTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVRLDVRRIESLKDGTDVVGNRTRVKVVKNKVAAPFKQAEFDIMYGKGISREGSLIDVGVEQSIIRKSGAWYTYDGDQLGQGKEKAREFLKENPDVAAEIEKKILEKLGVGQTSGDAAGGPELPPVDF
>NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein
MRLTDFWGRLEQAFGAAYARSIAADHAFAELDGRTIEQAIAQGVDTATIWRAVVASYPDRVPSRLH
>NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein
MSRTGGPVGAQQWVPPRPHSIDELKQAAAGCHGCELYENATQTVFGRGAPNAKIVFVGEQPGDIEDQKGLPFVGPAGRLLRDAVDDAGIDPADLYITNSVKHFRFELRGARRIHQSPGPAHITACRPWLVSEFALLKPQLVVLLGATAGKALLGPSFRVNRSRGQLMPWPASAEHPEDFPVAEIRALATIHPSAVLRADNRDIAYQGLVDDLKIAAAAITA
>NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MAEQYQVSGGTAAEISASIETGVVRGDWQFGAALPPVRVLATALHVSPATVAKAYQELRQRGVVETEGRRGTRVRSRPPVALSRSALRPPVPAGLLNLSSGEPDLSLLPPLGPALRVIADQVGPPQGYTSAATMPELIEAARPRLLAEGVPVAEAAIAVTAGALDSIERLLTAHLRPGDAVAVEDPGWANLMDLIAALGMRPLPVAVDPDGPEPGSLDAALRAGARAVVITVRAQNPTGAAVSAIRAAELRDLLSDHPDTLLIEDDHAAELAEAPPHCVGPVTRWWAFVRSASKPFGPDLRIAVLAGDETSIARVAGRMRIGMGWVSTVAQRLLLQLWRDPEVTELVAAAARSYGSRRRRLRHLLQARGVRSSGDTGINVWVPVPDETHAIAGLRDAGYAVAPGALFRIASPPGIRITVSPLAESDIEALADAVSTVVHPAATGLPMR
>NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase
MTEVYATTDRTTATRTRQRMHYERDRAHAILDEAYDCSVAFVADGEPRVLPTLHVRVGETLYLHGSTGARLALGARGDGVPVCVSVTLLDGLVYGRSHFHHSANYRSVIAHGVARPVADPAEKAAAMHALVEKVGAGRAAGSRPPTDREMAQTSVLALPLAEVSARVREGGVVDEPADLDLPHWAGVLPIRRVAGPPESDAGVAVPPPAYLPGNPATEWQTPALMQGRLVRLEPLSPAHAAGLFEALDDEEVWRHIPQQRASSVADMAEDVAEVIRGQWRGDRAGWAQVDPVTGVVMGMTTYHDVDPDRRSVGIGHTMLGRRWWRTGVNTEAKLLLLERAFDVLGAAKVFWYTDIRNERSQQAIARLGAGRDGLLRRQRLRPDGTWRDTVVFAMTADEWPAAARRLRDRLAAG
>NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE
MLGITDFWTYVLGVVAIILLPGPNSIFVLSVGARRGVRAGYQAACGVFLGDTVLMVLSATGVSSLLGAYPPLFLVLKYAGAGYLAWVGAGILRGARARWRGRGEVSATEATEEPAEMQRPFRRAAVISLLNPKAILFFVSFFIQFVQPGYPHPALSFLVLGAVVQFFSALYLTALIFGGRFLVGQFQRRRRLAAGAATGVGALFVGFSIKLATASLS
>NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase
MAVRQMLVAGRYRLLEPVGAGGMGRVWLARDQMLDRDVAIKEIVPPDWMSEAEKDRLHSRTLREARSAARLTHPHVVRVYDVLHDDGVSWIVMEYVASRSLYQVLITQGPYSPVEAARIGLAVLDALNAAHRAGVLHRDVKPHNVLIGLDGRVLLTDFGLATFVDDGMVTTPGLIVGSPQYVSPERARDGASTVAADMWSFGATLYATVEGQSPYARDSAMATLAALATEPPNPPLRAGPIGPILEGLLRYAPEDRLSADETERRLRAVLGETGPAAAARPATVVAPVTRMVAEDSPTVAAVAPPSEAKTDSDRTEVVPVATGELVRTADLAGTGLVLEGESGPAEFPEEDEADHDDDAEDSDGWWQSGRGYIDGTFTVTDDLDAGSVPAAAGHSHYGAGRWTDGGNRAPSSSGVPRAHHNRQPSAAGRPAATRLLRRGNQATVRGIPSPRSPVSGPLPDTGVPPGRWALHPLPAKRISTRAVLAGLLAVALISGSLLSVHLMQRDDSAPQMVHSPMPAPSGMSSSGMSPSDMSPSDMSPSGMSSSGMPASGMSPSSRASAPEAGASQPRASPTGSVSPVTAGFSPIVCDAPAPHHAPVAPQAGAGRGVDGWRLQAGWSYFTDGTGFHLPVPDGWTYQRIGSTYCFREPRGGRVLSLDVGRPAATAPLQGCRAEDRRLRASRQVRDYRAMSLAPVVLLHAAVDWEFRYRTSGGVLRRARTRWLSMGGRAYALGWATPEAAWAAELGKLEMVWSTFYTDGGTPASASRG
>NZ_LT827010.1|WP_043512820.1|7929414_7934382_+|DEAD/DEAH-box-helicase
MVGVREVLENFGPATRAWFTAAFAAPTAAQDGAWRAIGAGRHALVVAPTGSGKTLAAFLWSLDRLAREPVPEQVRRRCRVLYVSPLKALAVDVERNLRAPLTGIRQAAGRLGLPPPEITVGMRTGDTPADERRGFARTPPDILITTPESLFLLLTSAARESLRGVETVIIDEVHAVAATKRGAHLALSLERLDALLDRPAQRIGLSATVRPIEETARFLGGPQHVEIVRPPSTKTIDVTVQVPVEDMTRLDESPAGDDLDGGRHTPSIWPAVEERVLDLIEGHRSTIVFTNSRRGAERLCARLNELSAERVELARLGEQAAEHGEVPWRGGSGDPVGPPGAAPQARLDGPTAGAKAGLDELGAGPPAGLDELGTGLPAGLDELGTGLPAGLDELGTGLPAGLDELGAGPSADSLGSGMPMGRGGGRFRRTGKATSGTGNGPAPGGRPGGKPAGFRGNGAAGMPAAVMAQAGATLGAAPVVARAHHGSVSREERKQIEEALKSGRLPAVVATSSLELGIDMGAVDLVVQIEAPPTVAAGLQRIGRAGHQVGAVSRGVVFPKHRGDLLSCAVVAERMSEGAIEELRYPRNPLDVLAQQIVAMVALDAWPVDELAALIRRAAPFAELPESALHAVLDMLSGRYPSTAFAELRPRLVWDRGTDLLTGRPGAQRLAVTSGGTIPDRGMFGVFLAGSEKASRVGELDEEMVYESRVGDVFLLGSTSWRIEDITPDRVLVSPAPGAPARMPFWKGDSPGRPIELGRAIGARLRALVKAGDERATTALRESGLDEWAAGNLVNYLREQRESTRHLPDDRTIVVERFRDELGDWRMTVHCVLGARVNAPWALAIGRRLGERFGVDGQVMPSDDGIVIRLPDTAEEPPGADLVAFDPEEILQIVEESVGTSALFASRFRECAARSLLLPRRDPRRRQPLWQQRQRSAQLLDVAREFADFPVTLEAARECLQDVFDVPGLTGLMREIAGRKVRLVETETPRPSPFARSLLFGYVGAFLYEGDAPLAERRAAALALDATLLGELLGRVDLRELLDPGVVTETEAQLQWRTTQRSPRDAEDAAELLRLLGDLSPAELAERGVPEDWVVSLESARRAIRVRVAGEERWIGVDDAGRYRDALGVALPVGLAEAYLEPVADPLGDLVARYARTHGPFLAATCAARFGLGVFVVEQALKRLSATGRVTSGEFSPDGAGTEWCDAEVLRMLRRRSLAALRREIEPVPPKVLAAFLPRWHQVGGNARGVDALAAVIEQVQGLAVPASAWERLVLPARIADYAPPQLDELCGSGEVLWAGSGSIAGGDGWVTLAYADSAPLLLPPPDEEFALTPAHQAVLDALGDGQALFFRSLSDRAGSTDDTDLAAVVWDLVWAGHLTNDTFAPLRALLGGSGAHRAKAAPARSRYRRPGRPHLPSRTGPLNMAGRWSRLPDRDPDPTRRAAALADLLLERHGVVTRGAVMAEGVTGGFAAVYPVLSALEERGAARRGYFVEGLGAAQFAVPGAVDRLRALAEPAELAKRTGAGGLVLAASDPANPYGAALPWPERIVDSGDGEPVAKAGHRAGRKAGALVVLVGGELVLYVERGGRTLLSFADDPEALTAAGQALAASVRSGALGAMSVERADGESVHASPLREALTAAGFRATPRGLRLRG
>NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase
MRLVIFTEPQQGASHDDLLRVAKAAEDGGFDGFFRSDHYVKMGDVSGAPGPSDAWITLAALAVQTSRIRLGTLVSSATFRLPGPLAIAVAQVDAMSGGRIEFGLGGGWFDTEHQAYGIPFPPLGERFDRLDEQLQVITGLWGTPAGETFSFDGKHYRLTDSPALPKPVQSPLPVIVGGHGKKRTPDLAARFAAEFNVPFSKIDELPAHFDRVRAASAAIGRAEPPAFSAAAVLCAGRDDTELRRRAAAIGREVEEMRESGGVVGTPGEVVETIKRYAEAGASRLFLQVLDLSDIEHIELVASEVLPHI

Crispr_ID: NZ_LT827010_20

• CRISPR_ID: NZ_LT827010_20
• CRISPR_location: 7934208-7934449
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT827010_20

Consensus_repeat	Method
GCGGCGCCGCTGCGGGAGGCGCTGACCGCCGCCGGGTTCCGGGCTACGCCGCG	PILER-CR

spacers of NZ_LT827010_20

>20.1|7934268|71|NZ_LT827010|PILER-CR
CAGGCGCTGGCCGCCTCGGTGCGGTCCGGGGCGCTCGGGGCGATGTCGGTGGAACGGGCGGACGGAGAATC
>20.2|7934399|36|NZ_LT827010|PILER-CR
CGGGTTGCGGCTACGAGGGTGAGCGGCGGCGGGTGA

CRISPR arrays and Neighbor proteins around NZ_LT827010_20

CRISPR arrays

The CRISPR arrays of NZ_LT827010_20

>merge|NZ_LT827010|20|7934208-7934449|PILER-CR
GGAGGCGCTGACCGCGGCCGGGCAGGCGCTGGCCGCCTCGGTGCGGTCCGGGGCGCTCGGGGCGATGTCGGTGGAACGGGCGGACGGAGAATCGGTGCATGCGTCGCCGCTGCGGGAGGCGCTGACCGCCGCCGGGTTCCGGGCTACGCCGCGCGGGTTGCGGCTACGAGGGTGAGCGGCGGCGGGTGAGCGGCGGCGCTGCGGGAGGCGCTGACCGCCGCCGGGTTCCGGGCTACGCCGCG

>NZ_LT827010|20|2|7934208-7934449|PILER-CR
GGAGGCGCTGACCGCGGCCGGGCAGGCGCTGGCCGCCTCGGTGCGGTCCGGGGCGCTCGG	GGCGATGTCGGTGGAACGGGCGGACGGAGAATCGGTGCATGCGTCGCCGCTGCGGGAGGCGCTGACCGCCG
CCGGGTTCCGGGCTACGCCGCGCGGGTTGCGGCTACGAGGGTGAGCGGCGGCGGGTGAGC	GGCGGCGCTGCGGGAGGCGCTGACCGCCGCCGGGTT
CCGGGCTACGCCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|378988
NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein	unknown	unknown	gnl|CDD|274850
NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease	unknown	unknown	gnl|CDD|223836
NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274648
NZ_LT827010.1|WP_014694134.1|7943619_7944093_+|DUF3291-domain-containing-protein	unknown	unknown	gnl|CDD|378694
NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE	unknown	unknown	gnl|CDD|236807
NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA	unknown	unknown	gnl|CDD|236476
NZ_LT827010.1|WP_014694131.1|7940791_7941382_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl|CDD|273139
NZ_LT827010.1|WP_014694125.1|7935576_7936368_+|SAM-dependent-chlorinase/fluorinase	unknown	unknown	gnl|CDD|376645
NZ_LT827010.1|WP_014694133.1|7942927_7943587_+|transcriptional-regulator	unknown	unknown	gnl|CDD|225222
NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein	unknown	unknown	gnl|CDD|378612
NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX	unknown	unknown	gnl|CDD|234646
NZ_LT827010.1|WP_014694128.1|7938331_7939195_-|PspA/IM30-family-protein	unknown	unknown	gnl|CDD|224755
NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl|CDD|185378
NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT827010.1|WP_014694132.1|7941378_7942839_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|273453
NZ_LT827010.1|WP_099344227.1|7940242_7940728_-|CinA-family-protein	unknown	unknown	gnl|CDD|334938
NZ_LT827010.1|WP_014694129.1|7939682_7940081_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_LT827010.1|WP_043512821.1|7944214_7946704_-|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y	unknown	unknown	gnl|CDD|237177

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	1.46684e-43
NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein	gnl|CDD|274850	TIGR03914, SPO1_DNA_polymerase-related_protein, uracil-DNA glycosylase family domain. This model represents a clade within the uracil-DNA glycosylase superfamily. Among characterized proteins, it most closely resembles the Thermus thermophilus uracil-DNA glycosylase TTUDGA, which acts uracil (deamidated cytosine) in both single-stranded DNA and U/G pairs of double-stranded DNA. This domain may occur either as a stand-alone protein or as the C-terminal domain of a fusion with another domain that always pairs with a particular radical-SAM family protein.	2.57656e-78
NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.06035e-45
NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase	gnl|CDD|274648	TIGR03560, F420_Rv1855c, probable F420-dependent oxidoreductase, Rv1855c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity].	8.6841e-103
NZ_LT827010.1|WP_014694134.1|7943619_7944093_+|DUF3291-domain-containing-protein	gnl|CDD|378694	pfam11695, DUF3291, Domain of unknown function (DUF3291). This bacterial family of proteins has no known function.	1.35294e-65
NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE	gnl|CDD|236807	PRK10958, PRK10958, leucine export protein LeuE; Provisional.	2.95095e-106
NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA	gnl|CDD|236476	PRK09354, recA, recombinase A; Provisional.	0
NZ_LT827010.1|WP_014694131.1|7940791_7941382_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl|CDD|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	9.77405e-30
NZ_LT827010.1|WP_014694125.1|7935576_7936368_+|SAM-dependent-chlorinase/fluorinase	gnl|CDD|376645	pfam01887, SAM_adeno_trans, S-adenosyl-l-methionine hydroxide adenosyltransferase. This is a family of proteins, previously known as DUF62, found in archaebacteria and bacteria. The structure of proteins in this family is similar to that of a bacterial fluorinating enzyme. S-adenosyl-l-methionine hydroxide adenosyltransferases utilizes a rigorously conserved amino acid side chain triad (Asp-Arg-His) which may have a role in activating water to hydroxide ion. This family used to be known as DUF62.	6.33429e-92
NZ_LT827010.1|WP_014694133.1|7942927_7943587_+|transcriptional-regulator	gnl|CDD|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	1.07682e-27
NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein	gnl|CDD|378612	pfam11248, DUF3046, Protein of unknown function (DUF3046). This family of proteins with unknown function appears to be restricted to Actinobacteria.	4.65091e-24
NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX	gnl|CDD|234646	PRK00117, recX, recombination regulator RecX; Reviewed.	2.75018e-34
NZ_LT827010.1|WP_014694128.1|7938331_7939195_-|PspA/IM30-family-protein	gnl|CDD|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	1.7658e-28
NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl|CDD|185378	PRK15481, PRK15481, transcriptional regulatory protein PtsJ; Provisional.	2.90805e-94
NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.12818e-101
NZ_LT827010.1|WP_014694132.1|7941378_7942839_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	1.15022e-124
NZ_LT827010.1|WP_099344227.1|7940242_7940728_-|CinA-family-protein	gnl|CDD|334938	pfam02464, CinA, Competence-damaged protein. CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. This Pfam family consists of putative competence-damaged proteins from the cin operon. Some members of this family have nicotinamide mononucleotide (NMN) deamidase activity.	1.95654e-53
NZ_LT827010.1|WP_014694129.1|7939682_7940081_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.26497e-09
NZ_LT827010.1|WP_043512821.1|7944214_7946704_-|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	3.86942e-142
NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0

Protein sequences

>NZ_LT827010.1|WP_014694122.1|7926987_7929294_-|serine/threonine-protein-kinase
MAVRQMLVAGRYRLLEPVGAGGMGRVWLARDQMLDRDVAIKEIVPPDWMSEAEKDRLHSRTLREARSAARLTHPHVVRVYDVLHDDGVSWIVMEYVASRSLYQVLITQGPYSPVEAARIGLAVLDALNAAHRAGVLHRDVKPHNVLIGLDGRVLLTDFGLATFVDDGMVTTPGLIVGSPQYVSPERARDGASTVAADMWSFGATLYATVEGQSPYARDSAMATLAALATEPPNPPLRAGPIGPILEGLLRYAPEDRLSADETERRLRAVLGETGPAAAARPATVVAPVTRMVAEDSPTVAAVAPPSEAKTDSDRTEVVPVATGELVRTADLAGTGLVLEGESGPAEFPEEDEADHDDDAEDSDGWWQSGRGYIDGTFTVTDDLDAGSVPAAAGHSHYGAGRWTDGGNRAPSSSGVPRAHHNRQPSAAGRPAATRLLRRGNQATVRGIPSPRSPVSGPLPDTGVPPGRWALHPLPAKRISTRAVLAGLLAVALISGSLLSVHLMQRDDSAPQMVHSPMPAPSGMSSSGMSPSDMSPSDMSPSGMSSSGMPASGMSPSSRASAPEAGASQPRASPTGSVSPVTAGFSPIVCDAPAPHHAPVAPQAGAGRGVDGWRLQAGWSYFTDGTGFHLPVPDGWTYQRIGSTYCFREPRGGRVLSLDVGRPAATAPLQGCRAEDRRLRASRQVRDYRAMSLAPVVLLHAAVDWEFRYRTSGGVLRRARTRWLSMGGRAYALGWATPEAAWAAELGKLEMVWSTFYTDGGTPASASRG
>NZ_LT827010.1|WP_014694121.1|7926148_7926802_+|leucine-efflux-protein-LeuE
MLGITDFWTYVLGVVAIILLPGPNSIFVLSVGARRGVRAGYQAACGVFLGDTVLMVLSATGVSSLLGAYPPLFLVLKYAGAGYLAWVGAGILRGARARWRGRGEVSATEATEEPAEMQRPFRRAAVISLLNPKAILFFVSFFIQFVQPGYPHPALSFLVLGAVVQFFSALYLTALIFGGRFLVGQFQRRRRLAAGAATGVGALFVGFSIKLATASLS
>NZ_LT827010.1|WP_014694120.1|7924884_7926126_+|GNAT-family-N-acetyltransferase
MTEVYATTDRTTATRTRQRMHYERDRAHAILDEAYDCSVAFVADGEPRVLPTLHVRVGETLYLHGSTGARLALGARGDGVPVCVSVTLLDGLVYGRSHFHHSANYRSVIAHGVARPVADPAEKAAAMHALVEKVGAGRAAGSRPPTDREMAQTSVLALPLAEVSARVREGGVVDEPADLDLPHWAGVLPIRRVAGPPESDAGVAVPPPAYLPGNPATEWQTPALMQGRLVRLEPLSPAHAAGLFEALDDEEVWRHIPQQRASSVADMAEDVAEVIRGQWRGDRAGWAQVDPVTGVVMGMTTYHDVDPDRRSVGIGHTMLGRRWWRTGVNTEAKLLLLERAFDVLGAAKVFWYTDIRNERSQQAIARLGAGRDGLLRRQRLRPDGTWRDTVVFAMTADEWPAAARRLRDRLAAG
>NZ_LT827010.1|WP_014694119.1|7923474_7924821_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MAEQYQVSGGTAAEISASIETGVVRGDWQFGAALPPVRVLATALHVSPATVAKAYQELRQRGVVETEGRRGTRVRSRPPVALSRSALRPPVPAGLLNLSSGEPDLSLLPPLGPALRVIADQVGPPQGYTSAATMPELIEAARPRLLAEGVPVAEAAIAVTAGALDSIERLLTAHLRPGDAVAVEDPGWANLMDLIAALGMRPLPVAVDPDGPEPGSLDAALRAGARAVVITVRAQNPTGAAVSAIRAAELRDLLSDHPDTLLIEDDHAAELAEAPPHCVGPVTRWWAFVRSASKPFGPDLRIAVLAGDETSIARVAGRMRIGMGWVSTVAQRLLLQLWRDPEVTELVAAAARSYGSRRRRLRHLLQARGVRSSGDTGINVWVPVPDETHAIAGLRDAGYAVAPGALFRIASPPGIRITVSPLAESDIEALADAVSTVVHPAATGLPMR
>NZ_LT827010.1|WP_014694118.1|7922343_7923009_-|UdgX-family-uracil-DNA-binding-protein
MSRTGGPVGAQQWVPPRPHSIDELKQAAAGCHGCELYENATQTVFGRGAPNAKIVFVGEQPGDIEDQKGLPFVGPAGRLLRDAVDDAGIDPADLYITNSVKHFRFELRGARRIHQSPGPAHITACRPWLVSEFALLKPQLVVLLGATAGKALLGPSFRVNRSRGQLMPWPASAEHPEDFPVAEIRALATIHPSAVLRADNRDIAYQGLVDDLKIAAAAITA
>NZ_LT827010.1|WP_014694117.1|7921664_7921865_-|DUF3046-domain-containing-protein
MRLTDFWGRLEQAFGAAYARSIAADHAFAELDGRTIEQAIAQGVDTATIWRAVVASYPDRVPSRLH
>NZ_LT827010.1|WP_043512814.1|7920440_7921487_-|recombinase-RecA
MVAAPDREKALELALAQIDKQFGKGSVMRLGERPVVQTAVIPTSSIALDVALGVGGLPRGRVIEVYGPESSGKTTVALHAVANAQKAGGTAAFIDAEHALDPDYARALGVDTDALLVSQPDTGEQALEIADMLIRSGALDIIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITGVLNNTGTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVRLDVRRIESLKDGTDVVGNRTRVKVVKNKVAAPFKQAEFDIMYGKGISREGSLIDVGVEQSIIRKSGAWYTYDGDQLGQGKEKAREFLKENPDVAAEIEKKILEKLGVGQTSGDAAGGPELPPVDF
>NZ_LT827010.1|WP_080128271.1|7919220_7919859_-|regulatory-protein-RecX
MGGPEGEGSDGRFALRAGARGGGGAGERKPAGPAQSESERAREICLRQLAVRPRTRAELAKVLARKEISEEVIAEVLDRYDEVGIINDAAFARAWVSSRHHGRGLARRALANELRQRGVDAEVAGEALESVDDESEAETARALVDRKLRTASGTPEAVFRRLVAMLARKGYPVGIAIRAVKEALAARDAEAAEFADAVDADALADQAEDPHS
>NZ_LT827010.1|WP_014694114.1|7915575_7917300_-|ribonuclease-Y
MAPQYWVLVVAIVVLAVSVIVGLTLGARALGQLRTERQDAHDRQEQEVGVAQAKVADANAKAASVRAEAAAAKAEAAAARAEARRVLENAHSEADTILEHAHRQAEADVEQLRTAARRSGEREIALLNATVKEQAAEVERRAARIDERERLHGEEVERLVERERRLVALESELAKREATLKARETEVEAAENTKRRELERIAGLTTETAKGELIDAIEGQAKREAAILIRDIEQDARSTADTRARHIVVDAIQRIASEQTAESVVSVLHLPSDEMKGRIIGREGRNIRAFESTTGVNLIIDDTPEAVLLSCFDPVRREVGRLTLEKLVLDGRIHPHRIEEVFDSAKNEVERLCDRAAEEALVDVGITNIHPELVKLLGRLRYRTSYGQNVLKHLVETAHIAGIMAAELGLDVPIMKRAAFLHDIGKALTHEVEGSHALIGADVARKYGEHEEIVHAIEAHHNEVPPQTIEAVLTQASDACSGGRPGARRESLEAYVKRLERIEEIAGGKLGVEKVFAMQAGREIRVMVRPDDIDDIGAAVLARDVAKQIEEELTYPGQIRVTVVRESRVTELAR
>NZ_LT827010.1|WP_014694113.1|7914528_7915497_+|amino-acid-ABC-transporter-permease
MSQQSVLYDVPGPRQRRITLISSLLVAIGLLAGIYYLIYLPLHHKGQFSMKLWGPLIDPGNEDFSAVWDRIGVGVKNTLTAAVFAIIGSLIIGTLLSVLRIELESLARRRFPGIAAPVALLLRALSVALAWATRICIEVFRGLPVVLTIFFVARGLPEFGVSMDTLWYLVIGLTIYNSVVIGEILRSGMTGLPPGQREAAAAIGLSSPQTTMIVLLPQAFRIMLPALISQLVVVLKDTSLGFIISYEETLNIGKQIIGVLSNPIQVYAVIGTLFILVNYSLSKLAQYVQRRLSRGRKTAGMPRRQPPTAALIAQAEGAGGTA
>NZ_LT827010.1|WP_014694124.1|7934577_7935504_-|LLM-class-F420-dependent-oxidoreductase
MRLVIFTEPQQGASHDDLLRVAKAAEDGGFDGFFRSDHYVKMGDVSGAPGPSDAWITLAALAVQTSRIRLGTLVSSATFRLPGPLAIAVAQVDAMSGGRIEFGLGGGWFDTEHQAYGIPFPPLGERFDRLDEQLQVITGLWGTPAGETFSFDGKHYRLTDSPALPKPVQSPLPVIVGGHGKKRTPDLAARFAAEFNVPFSKIDELPAHFDRVRAASAAIGRAEPPAFSAAAVLCAGRDDTELRRRAAAIGREVEEMRESGGVVGTPGEVVETIKRYAEAGASRLFLQVLDLSDIEHIELVASEVLPHI
>NZ_LT827010.1|WP_014694125.1|7935576_7936368_+|SAM-dependent-chlorinase/fluorinase
MAGYGWISFTTDYGTFDGFVAACHGSIARVAPDVRVIDVTHHVPPADVTRGAAVLAQTAPHLPPSVHLAVVDPGVGTARRGVVLATPGGLLVGPDNGLLIWAAESLGGITAAHELGNKEWTLGDVSRTFHGRDVFAPAAARLAGGAAPSEAGPALDPASLVRLPDPVASVGDGWIEAEVLTVDRFGNVQLAAEGALLSGLGTELTVNGTVRARRGATFADVGAGELLVYTDSADQVAIAVNNGRAVVVLSVVPGDMVRIAERR
>NZ_LT827010.1|WP_014694128.1|7938331_7939195_-|PspA/IM30-family-protein
MANPFVKGWHYMMALFGAKIDEYADPKVQIQQAIEDAQRQHQALVQQAAAVIGNQRQLEMKLSRQMSEVEKLQGMARQALVLADRARAAGDEAEAQKYEQTAQTLATQLVSGEQSMEDLKTLHDQALGAAGQARKAVENNAMVLQQRIAERSRLLSQLEQAKMQETVAKSLESMSQLAAPGNTPSLDQVRDKIEQRYASAMGRAELASNSVEGRMLEVQKSSLDLAGSSRLEQIRASMAGDKLGGAAAQPAVGGQQNATPADAAGVARLDEIRASMNQKRGDTTAAG
>NZ_LT827010.1|WP_014694129.1|7939682_7940081_-|helix-turn-helix-transcriptional-regulator
MVLLRRVIGDALRARRQGQHRTLREVSTAANVSLGYLSEIERGQKEASSELLAAICDALGARLSELLSEVSSTLSLAENMEGVLVPVDDKPGEPARQVATDGSVSVSVRQESPLKATLHATRNKKRDVVYAA
>NZ_LT827010.1|WP_099344227.1|7940242_7940728_-|CinA-family-protein
MPVAAAAAVHMLVERRQTLATAESLTGGLVAATIVEIPGVSAVYRGGLVVYATELKGTLAGVPAALLAERGPVDPDVAGRLAEGARDRCGADWGLATTGVAGPEPQDGKPVGLVYVAVAGPPGTRVRELNLTGNRAAVRTESVTAVLQLLTDVLRAAPASV
>NZ_LT827010.1|WP_014694131.1|7940791_7941382_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MTDEPVPVAAPRVVSLYNAANALTVVRLILVPVFLALVVASRMTDHDWRVGACLAFCVASATDFVDGWIARRWHLVTSFGKIADPIADKALTGTALVLLSAYDVLPWWITVLILAREWGVTALRFWVIRYGVIPASRGGKLKTGLQTLAIVWYLWPVPAPFDVVGPWVMYAALLVTVATGFDYVVQALRLRRTAGV
>NZ_LT827010.1|WP_014694132.1|7941378_7942839_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MSVTPPPSRRVALLTLGCARNEVDSEELAARLDAEGWEVGTDAAKADVVLVNTCGFVEKAKQDSIDTLLAAADTGAKVVAAGCMAERYGRELAENLPEADAVLGFDDYTDIATRLNGVLAGEKFDAHTPRDRRELLPITPVQRHAAKVVVPGHATVDEHTPAHLRKVLRRRLDNSPVASLKLASGCDRRCAFCAIPAFRGAFVSRDPQELLAEAEWLARTGVRELVLVSENSTSYGKDLGDPRLLEKLLPQLAAVDGIVRVRASYLQPAETRPGLVEAIAGTPGVAAYYDLSFQHSSEPVLRRMRRFGSTERFLELLDSARRLAPEAGARSNFIVGFPGETRQDVDELVRFLTEARLDAIGIFDYSDEDGTEAAGLPGKVRPETVKRRYDRVVALAEELCAQRAEDRLGSIVEVLVDTIDDGEIEGRAEHQAPEVDGSTTLVAGDQGVDLAALRPGDLVRARVTGTEGVDLIAVPTEMISAAQADR
>NZ_LT827010.1|WP_014694133.1|7942927_7943587_+|transcriptional-regulator
MTTSEDLGDLDAVTSLADGVRRQAYRTVAASRAPVGRDEVAEALGVGRTLAAFHLDKLVAAGLLETSYARRSGRTGPGAGRPAKLYRVATAEHVVSVPPRAYRTAAELLAEALEETGAEETLNRVARRHGERAAAAEGDVFEVLAGHGYGPVADGPERIELRNCPFHRLAEQFPPVICGMNLAMVDGLLTGAGLDAGWQARMDAAPGRCCVALCKKQTD
>NZ_LT827010.1|WP_014694134.1|7943619_7944093_+|DUF3291-domain-containing-protein
MSAFHLAQINTARLRAPLADPSMAEFVAGLTLMNELADRSPGFVWRLIGDDGDGTIATDADPGRIYTMSVWETPAHLRAYAYQSDHLDYLRRRREWFHPHGPDAALVLWWLPAGDLPTLQQGLDRLDRLRADGSTPEAFTFRAPFPAPVLSETTHGR
>NZ_LT827010.1|WP_043512821.1|7944214_7946704_-|DNA-translocase-FtsK
MAGRTPPASRGRAASTPRGAATSRARQPARQPAKKAAAPRKRTAATAKRAAPPPMVGPAVGRGISAVWMGLATSVGWVARGAGRNARNIGPEHRRDGAGLLLLGFSILTAVAVWGRGAGPVGQRLADAVHLFFGGLGVLLPLLFFYGAIRLMRQPADPEHRGRNPVGWSAIIIAIASLLYISGPKGDDVALTGNGGLLGYGVGSVLERAVSVWVAVPLLILLFVFGLLVITATPINRIPERFVLLGELVTGRNRPVLEDDVEDDPVAEDEEARPARARRRKPSPVVPLDEMLEPEEPDEDLILHDTVVLPKVPATRRKPPPPDHSPAPVKVEQLEISAVDSGDYQRPPVSLLAEGAPAKARSRANDEIMAALTGVFEQFNVDAVVTGFTRGPTVTRYEVEIGPGTKVERITQLSRNIAYAVKSPDVRILSPIPGKSAVGVEIPNTDPENVSLGDVLRSPLAQRDHHPMVVALGKDIEGGFVTANLAKMPHILIAGATGAGKSSCLNSLLVSLLTRATPDQVRLLLVDPKRVEMTAYEGIPHLVTPIVTNPKKAADALEWVVREMDMRYDDLAANGVRHIDDFNRKVRNGEITAPPGSERVIKPYPYLLVIVDELADLMMVAPRDVEDSVVRITQLARAAGIHLVLATQRPSVDVVTGLIKANVPSRLAFATSSLADSRVILDQPGAEKLLGRGDGLFLPMGASKPTRIQGAWVDEKEIAAVVKFCKDQREPEFQEGVTDAPPTKKREIDEEIGDDLQLLIQAIELVVTSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKARDVLIKPDELEESLAALKVD

Crispr_ID: NZ_LT827010_21

• CRISPR_ID: NZ_LT827010_21
• CRISPR_location: 8357267-8357331
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_21

Consensus_repeat	Method
GCACAACGCCGCGCGACGAAGCAC	CRISPRCasFinder

spacers of NZ_LT827010_21

>21.1|8357291|17|NZ_LT827010|CRISPRCasFinder
AGCGCCGCGCAGATGAC

CRISPR arrays and Neighbor proteins around NZ_LT827010_21

CRISPR arrays

The CRISPR arrays of NZ_LT827010_21

>merge|NZ_LT827010|21|8357267-8357331|CRISPRCasFinder
GCACAACGCCGCGCGACGAAGCACAGCGCCGCGCAGATGACACGCGACGCCACGCAAGCAAGCAC

>NZ_LT827010|21|18|8357267-8357331|CRISPRCasFinder
GCACAACGCCGCGCGACGAAGCAC	AGCGCCGCGCAGATGAC
ACGCGACGCCACGCAAGCAAGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_172898929.1|8364252_8365728_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NZ_LT827010.1|WP_043512929.1|8353952_8354657_-|FadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
NZ_LT827010.1|WP_080128278.1|8352645_8352906_-|S26-family-signal-peptidase	unknown	unknown	gnl|CDD|119398
NZ_LT827010.1|WP_014694499.1|8356504_8356759_+|WhiB-family-transcriptional-regulator	unknown	unknown	gnl|CDD|376791
NZ_LT827010.1|WP_043512934.1|8363008_8364025_-|SIS-domain-containing-protein	unknown	unknown	gnl|CDD|225132
NZ_LT827010.1|WP_014694508.1|8366340_8366625_-|mycothiol-system-anti-sigma-R-factor	unknown	unknown	gnl|CDD|274904
NZ_LT827010.1|WP_014694490.1|8349486_8349645_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694503.1|8359203_8360895_-|nitrite/sulfite-reductase	unknown	unknown	gnl|CDD|223233
NZ_LT827010.1|WP_014694504.1|8361440_8362979_-|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl|CDD|378836
NZ_LT827010.1|WP_014694491.1|8349988_8350930_-|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176227
NZ_LT827010.1|WP_014694494.1|8353039_8353444_+|superoxide-dismutase,-Ni	unknown	unknown	gnl|CDD|378114
NZ_LT827010.1|WP_014694498.1|8355142_8356093_+|diacylglycerol-kinase	unknown	unknown	gnl|CDD|224513
NZ_LT827010.1|WP_014694495.1|8353539_8353947_+|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|235217
NZ_LT827010.1|WP_014694497.1|8354695_8355073_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694501.1|8358287_8359052_-|phosphoadenylyl-sulfate-reductase	unknown	unknown	gnl|CDD|234997
NZ_LT827010.1|WP_172898928.1|8351274_8352432_-|NADP-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
NZ_LT827010.1|WP_014694502.1|8359048_8359207_-|hypothetical-protein	unknown	unknown	gnl|CDD|226202
NZ_LT827010.1|WP_014694500.1|8357397_8358306_-|cobalamin-biosynthesis-protein-CbiX	unknown	unknown	gnl|CDD|239509
NZ_LT827010.1|WP_014694507.1|8365729_8365945_-|biotin/lipoyl-binding-carrier-protein	unknown	unknown	gnl|CDD|237592
NZ_LT827010.1|WP_172898931.1|8366629_8367403_-|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|131992

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_172898929.1|8364252_8365728_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.03397e-07
NZ_LT827010.1|WP_043512929.1|8353952_8354657_-|FadR-family-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.43442e-46
NZ_LT827010.1|WP_080128278.1|8352645_8352906_-|S26-family-signal-peptidase	gnl|CDD|119398	cd06530, S26_SPase_I, The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are translocated across biological membranes. The bacterial signal peptidase I, which is the most intensively studied, has two N-terminal transmembrane segments inserted in the plasma membrane and a hydrophilic, C-terminal catalytic region that is located in the periplasmic space. Although the bacterial signal peptidase I is monomeric, signal peptidases of eukaryotic cells commonly function as oligomeric complexes containing two divergent copies of the catalytic monomer. These are the IMP1 and IMP2 signal peptidases of the mitochondrial inner membrane that remove leader peptides from nuclear- and mitochondrial-encoded proteins. Also, two components of the endoplasmic reticulum signal peptidase in mammals (18-kDa and 21-kDa) belong to this family and they process many proteins that enter the ER for retention or for export to the Golgi apparatus, secretory vesicles, plasma membranes or vacuole. An atypical member of the S26 SPase type I family is the TraF peptidase which has the remarkable activity of producing a cyclic protein of the Pseudomonas pilin system. The type I signal peptidases are unique serine proteases that utilize a serine/lysine catalytic dyad mechanism in place of the classical serine/histidine/aspartic acid catalytic triad mechanism.	6.90848e-12
NZ_LT827010.1|WP_014694499.1|8356504_8356759_+|WhiB-family-transcriptional-regulator	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	1.1712e-29
NZ_LT827010.1|WP_043512934.1|8363008_8364025_-|SIS-domain-containing-protein	gnl|CDD|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	1.83757e-73
NZ_LT827010.1|WP_014694508.1|8366340_8366625_-|mycothiol-system-anti-sigma-R-factor	gnl|CDD|274904	TIGR03988, antisig_RsrA, mycothiol system anti-sigma-R factor. Members of this family are the anti-sigma-R factor RsrA, which contains a CXXC motif as a thiol-disulphide redox switch. It interacts with sigma-R. It regulates and is regulated by the mycothiol system, which occurs in many actinomycetes. [Transcription, Transcription factors].	2.66643e-23
NZ_LT827010.1|WP_014694504.1|8361440_8362979_-|PAS-domain-containing-sensor-histidine-kinase	gnl|CDD|378836	pfam12282, H_kinase_N, Signal transduction histidine kinase. This domain is found in bacteria. This domain is about 150 amino acids in length. This domain is found associated with pfam07568, pfam08448, pfam02518. This domain has a single completely conserved residue P that may be functionally important. This family is mostly annotated as a histidine kinase involved in signal transduction but there is little published evidence to support this.	1.10706e-56
NZ_LT827010.1|WP_014694491.1|8349988_8350930_-|zinc-binding-dehydrogenase	gnl|CDD|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	2.61666e-90
NZ_LT827010.1|WP_014694494.1|8353039_8353444_+|superoxide-dismutase,-Ni	gnl|CDD|378114	pfam09055, Sod_Ni, Nickel-containing superoxide dismutase. Nickel containing superoxide dismutase (NiSOD) is a metalloenzyme containing a hexameric assembly of right-handed 4-helix bundles of up-down-up-down topology with an N-terminal His-Cys-X-X-Pro-Cys-Gly-X-Tyr motif that chelates the active site Ni ions. NiSOD catalyzes the disproportionation of superoxide to peroxide and molecular oxygen through alternate oxidation and reduction of Ni, protecting cells from the toxic products of aerobic metabolism.	3.08178e-65
NZ_LT827010.1|WP_014694498.1|8355142_8356093_+|diacylglycerol-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	5.75865e-45
NZ_LT827010.1|WP_014694495.1|8353539_8353947_+|anti-sigma-regulatory-factor	gnl|CDD|235217	PRK04069, PRK04069, serine-protein kinase RsbW; Provisional.	6.48518e-13
NZ_LT827010.1|WP_014694503.1|8359203_8360895_-|nitrite/sulfite-reductase	gnl|CDD|223233	COG0155, CysI, Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism].	3.20387e-165
NZ_LT827010.1|WP_014694501.1|8358287_8359052_-|phosphoadenylyl-sulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	6.46212e-108
NZ_LT827010.1|WP_172898928.1|8351274_8352432_-|NADP-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	1.86349e-177
NZ_LT827010.1|WP_014694502.1|8359048_8359207_-|hypothetical-protein	gnl|CDD|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00150808
NZ_LT827010.1|WP_014694500.1|8357397_8358306_-|cobalamin-biosynthesis-protein-CbiX	gnl|CDD|239509	cd03416, CbiX_SirB_N, Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase, responsible for the chelation of Co2+ into sirohydrochlorin, an important step in the vitamin B12 biosynthetic pathway. CbiX often contains a C-terminal histidine-rich region that may be important for metal delivery and/or storage, and may also contain an iron-sulfur center. Both are found in a wide range of bacteria. This subgroup also contains single domain proteins from archaea and bacteria which may represent the ancestral form of class II chelatases before domain duplication occurred.	8.49345e-19
NZ_LT827010.1|WP_014694507.1|8365729_8365945_-|biotin/lipoyl-binding-carrier-protein	gnl|CDD|237592	PRK14040, PRK14040, oxaloacetate decarboxylase subunit alpha.	3.86225e-20
NZ_LT827010.1|WP_172898931.1|8366629_8367403_-|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|131992	TIGR02947, putative_RNA_polymerase_sigma_factor, RNA polymerase sigma-70 factor, TIGR02947 family. This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and (with the exception of a paralog in Thermobifida fusca YX) one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria and each gene examined is followed by an anti-sigma factor in an apparent operon.	3.02343e-106

Protein sequences

>NZ_LT827010.1|WP_014694499.1|8356504_8356759_+|WhiB-family-transcriptional-regulator
MDWRHDAICRDEDPELFFPIGTSGPALLQVEQAKAVCRRCPVTEECLSWALESGQDAGVWGGMSEDERRAVKRRGGLRVSAPTA
>NZ_LT827010.1|WP_014694498.1|8355142_8356093_+|diacylglycerol-kinase
MRALLVVNPRATTTTERGRDVLVRALRSATDLTVRYTERRGHATVLARTAAEAGVDVVVTLGGDGTVNEAVNGLLTAPGALAGLPGPAAYRLPALAVVPGGSTNVFARALGLPRDWADGTSVILDGLRDGRHRVINLGRADDRYFTFAAGLGLDAAVVRRVEQARLRGRTSTPGLYLRAMVGQLLTETDRSDPPMTLERPGEEADTGLGTVIVQNTAPWTYAGNRPVDPNPDASFDLGLDVLALRKLKVSATTRTVTQLAWRSGDPHGKQVLRLHDLPEFTVISSRPQAFQLDGDYLGERQKVHFVSVPSALRVIC
>NZ_LT827010.1|WP_014694497.1|8354695_8355073_-|hypothetical-protein
MTTAAASLEWGVRLLYLQCAGLAGLTAYLIVLDLTRTGADVGVAAALTVLAALAAVAVFLVARALGRRRVRARGPAVVVQLFLLATGGFLVQVGPLWLGVVLLVVAAVTAVLVLLPASSRALGVD
>NZ_LT827010.1|WP_043512929.1|8353952_8354657_-|FadR-family-transcriptional-regulator
MTGSTVRPPAYQQLADDLRADITSGRLQPGERLPPEPELCVKIGVSRSTVREALRLLASQHLIVTTRGVTGGSFVAHPDAGQLAEGLSTGFALLAHSAGVGLADLLELRRALEVPAAGLAAMRRTDAHLAEMRAALFDPALDDLDTMLAAHSVFHRALAKATGNPLFELVGRPLYQASYGEEVVSDLPEQYWPRIDADHRELLDHLVARDAEAARQTASRHLDYIALTATVPRP
>NZ_LT827010.1|WP_014694495.1|8353539_8353947_+|anti-sigma-regulatory-factor
MSQLTQAEPEVGDDVVLLTVPADGGYLGVLRTATAGLAARLHFALDEIEDLRIAVDEACAMLLAIATRGAELECRFAVTDDALTVEVTVATVRGARLPSESSFAWKVLTALTTSAAAEANGQHATIRLLTRRTEY
>NZ_LT827010.1|WP_014694494.1|8353039_8353444_+|superoxide-dismutase,-Ni
MRLPRFLMPRTVVSAHCDLPCGVYDPAQARIEAESIKAIAEKYAANTDPEFRTRAILIKEQRAELVKHHLWVLWTDYFKAPHFEKYPNLHQLFNEATKLAGASGAKGSVDVAVADQLLGKIEEISKIFWETKQA
>NZ_LT827010.1|WP_080128278.1|8352645_8352906_-|S26-family-signal-peptidase
MAPALRHGDALLVRRGARVRTGDIVVARFRSRPGLLVVKRAVREQAGGWWIEGDNALVQDDSRAYGVADLIGRVVFRYYPRPGRLR
>NZ_LT827010.1|WP_172898928.1|8351274_8352432_-|NADP-dependent-malic-enzyme
MTMSATVPLASRDDLSLAYTPGVARVCEAIAADESLYPDYTWTSNTVAVVTDGSAVLGLGNIGPKAAMPVMEGKSVLFKQFGGVDSIPICLDTQDVEGIIAAVKAMAPSFGGINLEDISAPRCFEIERRLDAELDIPVFHDDQHGTAVVTLAALRNAAALLGRSFADLRVVISGAGAAGVAITNTLIAAGVQGANVIVVDSRGIIHADRTDLTATKADLAAATNVSGRTGGIAEALIGADVLVGVSGGSIPEEALSGMAPGAIIFALANPTPEVPPATAHKYAAIVATGRSDFPNQINNVLAFPGIFRGALDVRATTITDAMKVAAADAIAAIVADDLRPEAIVPSPLDPRVAPAVAAAVAAAAVRDGVARRTPALAPVQACQTV
>NZ_LT827010.1|WP_014694491.1|8349988_8350930_-|zinc-binding-dehydrogenase
MRAAYVSQLQPDEPLSGLTVGDLPFTPPAGWVPVEVRASSLNQHDVWSLRGVGLPADRLPMILGCDAAGVTPDGAAVLVYPVVEDKADPRGYSLFSERHPGTLAERVAAPRENLLPIPEGVSFAEAACLPTAWLTAYHMLVTRGRADRAGAILVQGAGGGVATAAVALGVALGKRVYATSRHQAKRDRIAELGAVAVEPGARLPERVDVVIESVGEPTFDHSMKCAAPGARIVVCGATAGHLARIDLRRVFAMQLEILGSSMGTPAELAELLQMCATGRIHPVIDSTHPFDATPDAFARLLSPDLFGKVVITH
>NZ_LT827010.1|WP_014694490.1|8349486_8349645_-|hypothetical-protein
MSDKSVDPSGNTEAFRAFTREPDDAAPSRMPLVIGGVVAAVIVIAVIAWLAL
>NZ_LT827010.1|WP_014694500.1|8357397_8358306_-|cobalamin-biosynthesis-protein-CbiX
MRSARLIAARPAVVLVAHGSRDPRAAASTEALARAVRRARPEWLVRAAYLDHAGPRPLDVLSGLGERRAVLVPLLLTAAYHGRVDLPAVLAEAAGLPVEVVLADVLGPLPVAPVDVLRPQPAPVAPADVPRPPAVALAEVLGPLPVGPAALLMPGLLLEALTRRLAGALGDFTDISSLVPNERFDAVVLSAAGTRDPVARGTVEHAAAALGARLGVPARVAYASGVGPRAGEAVRGLQEAGARRVAVAGYFLAPGLLYDQAVESAREAGAVAVAEPLGDAPELVGLISARVAATGVRVLAAA
>NZ_LT827010.1|WP_014694501.1|8358287_8359052_-|phosphoadenylyl-sulfate-reductase
MSILNATGLGLINLGAPSAPADPARRSADDLRALALQAAQDLEGRTAEEIAKWATDTFGARFCVTSSMADAVVAHLFSRVAPGVDVVFLDTGLHFPETLKVRDTVARTMNVNVRSIRPRMTVGQQDGEYGPRLFSRSPDECCFMRKVEPLERALTEYDAWATGLRRDESPTRANTPVVAFDAKKGKVKVNPIAAWTQADVDRYISRWNVPVNELFKKGYGSIGCWPCTRRTKAGEDPRAGRWAMFEKTECGLHV
>NZ_LT827010.1|WP_014694502.1|8359048_8359207_-|hypothetical-protein
MSDARSAPLYCPYCGEEDLRPNESSHGAWECHSCARVFTVKFNGLLSKGATK
>NZ_LT827010.1|WP_014694503.1|8359203_8360895_-|nitrite/sulfite-reductase
MAPSNTPATPAARPRKARGEGQWALGHREPLNPNERSKKDDNPLNVRARIENIYAHRGFASIDPADLRGRFRWWGLYTQRKAGIDGGRTAVLEPEELEDEYFMLRVRIDGGALSVAQLRTIADISTEFARDSADITDRQNIQLHWVRVEDVPEIWRRLEAVGLQTTEACGDCPRVVLGSPVAGISVDEVIDGTPAIDEILKRYIGDPAYSNLPRKFKSQISWLADGPYQANDVSFVGVEHPDHGPGFDLWVGGGLSTNPRLAERLGVWVPLAEIPDVWEGVVGIFRDYGYRRLRHRARLKFLLADWGVARFREVLEKEYLGRALIDGPAPDLPEKPIDHIGVHRQRDGKNYVGAAPVVGRSSGTQLGKLADLAERHGSDRVRLTAYQKLLVLDIADEKVETVVGELREIGLEARPSTWRRGTMACTGIEYCKLAIVETKARGEELVARLEERLPGFDADISVHLNGCPNACARTQVADIGLKGQLVMNAHGEQVEGFQIHLGGALGMAKGETAGFGRKLRGLKATAEELPAYVERVARNYRDGRTDGETFANWVMRAEEELLK
>NZ_LT827010.1|WP_014694504.1|8361440_8362979_-|PAS-domain-containing-sensor-histidine-kinase
MSTLRDLVEEHSSLGSADIDHLHRLAGDWQLLSDLSFADLLLWVPVKGDKPREFVCVAQVRPTTAPTAYQDDQVGRRFGGPEVAHLEVAFTQERIWREGDPVWYGDTPARHEAIPVRRRDENDHEEGYSEVIAVIGRDTNLSTARTPSQLELNYLTTADDLAQMVADGTFPPARQPGEMTTSAPRVGDGLIRLDASGKVTYASPNAQSAYRRLGFNAHLVGEELAGLSSRLAADPLEGNDVAERIRSSLRGEFPPRMEFEARGATVLTRSLPLLPAGVPIGALVLVRDVTEVRRRDRALMTKDATIREIHHRVKNNLQTVAALLRLQARRVDAPEARMALEESVRRVASIALVHETLSMSSDEAVEFDGIVDRVATAATEVSATSFPVHMRREGTFGILPAEIATSLVMVLNELLINAVEHGFPAGEDDEPAPAPEQPAEVVVAAHRFRKQLHVTVADNGQGLPEGFRPDAGRLGLQIVRALATGELRGSIELRNRAGGGTEAVLVVPLGKR
>NZ_LT827010.1|WP_043512934.1|8363008_8364025_-|SIS-domain-containing-protein
MAADIAEQPEGFARLLDGPHADAIAGVAAEIAARRPRNVLFVGRGTSDHAALYGAYLTEIRLGLPVASASPSAITLYGARPDFTGTLVIGVSQSGGSPDLTGVLSAARETGALTLAVTNNPESPLARAAELAVDVAAGHERAVAATKTYTAELLAMLLLVEGIRAGDGRLPAEERAALAGLPALAAGVLADHTAEDVAQRYRFAPHMVTTGRGYAYPTAREAALKLMETSYVPTLAFSGADLLHGPLAMTDTDVPVLAVVGGGPGGRSMADVLARLEERKADVLTVGPAGRLAVPPVDERYSPLLDILPLQKLALALALAKGEDPDAPRGLKKVTSTL
>NZ_LT827010.1|WP_172898929.1|8364252_8365728_+|tetratricopeptide-repeat-protein
MSQAARHLAGALPHAPTLPEIHELLSRLAARADGALDLFPLEPHAPAGRVAAHAHLLAAAGRPEDGLALLAAASGHTPDVDWAGVPWVSDPVLGGRIDPDALARTVMRLCTAVGDPAPAAAAEPLRPYLTVVRHTVAAHGEHAMLLGAGSALARRLGEARLAIDWATRGARSRPSKLGEIWLGYAFRSAGRIPEALAALRRAVMYDPDDLSVYADVAATLADLGRLDEALSWTDRALERDPRFDCVVHTAQRLRFRADGEVAHLIALADFVRDHPDDTHEHTDLDDCCRDVPWLSGLPASMSRLAPGRPTVNGDPSPDARDRLLRVASTGWPHPPAAYDRALGLVLVEPWELLALLGHPAVTGAADPGAAEVWACLGLLHHGSEEAWLDSTRRRLLLGLLDGEVDRVTQAALFALVTYAWVDPEARADVAAVVAGRFAEVAGGPHARAVAELALATPELARPARELAAATVRTPVIPRQRSRSYLLRWLKK
>NZ_LT827010.1|WP_014694507.1|8365729_8365945_-|biotin/lipoyl-binding-carrier-protein
MAEEVRAEMVANVWKVVAGVGQAVAEGDTLVILESMKMEIPVVAESDGTVGELAVHEGDVVQEGDLIAVIN
>NZ_LT827010.1|WP_014694508.1|8366340_8366625_-|mycothiol-system-anti-sigma-R-factor
MPSDETEHETDCSIVLSEVYLYLDLECSEDRRRLIQKHLDECSGCLREFGIEHEVKALVGRCCGDERAPAELRDRLRVKLVQLEAQTETREYLP
>NZ_LT827010.1|WP_172898931.1|8366629_8367403_-|sigma-70-family-RNA-polymerase-sigma-factor
MRERREATRVRELLDAPEWPATEPAPAAAPVSVSTPVFESVTGALPVSSAGRSRGESRVAQKERVDERRERFERDALPFVDQLYAAGLRMTRNPADAEDLVQETFLKAFSAFHQFEEGTNLKAWLYRILTNTYINSYRRKQRQPLQSPTEEITDWQLASSESHTSTGLRSAETEALDRLPDSDIKEALQSLPEDFRLAVYLADVEGFSYKEIADIMGTPIGTVMSRLHRGRRNLRQLLVGYAADRGITRAASEPQEA

Crispr_ID: NZ_LT827010_22

• CRISPR_ID: NZ_LT827010_22
• CRISPR_location: 8787065-8787245
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_LT827010_22

Consensus_repeat	Method
GCCGCCTCACCACCGCACACCGC	CRISPRCasFinder

spacers of NZ_LT827010_22

>22.1|8787088|43|NZ_LT827010|CRISPRCasFinder
CGTTCGCCACCACGACTCGGCGGACCGTTCCTCACCACCCCGG
>22.2|8787154|17|NZ_LT827010|CRISPRCasFinder
GACGAGCACCACGGGCG
>22.3|8787194|29|NZ_LT827010|CRISPRCasFinder
GGGCAACCTCACCGCCCCAAACCCAGCGC

CRISPR arrays and Neighbor proteins around NZ_LT827010_22

CRISPR arrays

The CRISPR arrays of NZ_LT827010_22

>merge|NZ_LT827010|22|8787065-8787245|CRISPRCasFinder
CCCGCCGCCCCGCCCCACCTCGCCGTTCGCCACCACGACTCGGCGGACCGTTCCTCACCACCCCGGCCGACCTCACCACCGCCCCGCCCGACGAGCACCACGGGCGGCCGCCTCACCACCGCACACCGCGGGCAACCTCACCGCCCCAAACCCAGCGCGCCGCCTCACCACCGCACACCGC

>NZ_LT827010|22|19|8787065-8787245|CRISPRCasFinder
CCCGCCGCCCCGCCCCACCTCGC	CGTTCGCCACCACGACTCGGCGGACCGTTCCTCACCACCCCGG
CCGACCTCACCACCGCCCCGCCC	GACGAGCACCACGGGCG
GCCGCCTCACCACCGCACACCGC	GGGCAACCTCACCGCCCCAAACCCAGCGC
GCCGCCTCACCACCGCACACCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_172898947.1|8785177_8785474_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|197951
NZ_LT827010.1|WP_043513080.1|8777693_8778692_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694926.1|8796136_8798842_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|224054
NZ_LT827010.1|WP_043516383.1|8798972_8801132_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|273521
NZ_LT827010.1|WP_014694928.1|8801134_8801458_-|DUF3263-domain-containing-protein	unknown	unknown	gnl|CDD|378688
NZ_LT827010.1|WP_014694908.1|8776697_8777414_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_LT827010.1|WP_099344241.1|8778726_8779554_+|DUF2993-domain-containing-protein	unknown	unknown	gnl|CDD|378597
NZ_LT827010.1|WP_014694925.1|8795264_8796140_-|ABC-transporter-permease-subunit	unknown	unknown	gnl|CDD|372253
NZ_LT827010.1|WP_014694921.1|8790453_8792076_-|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NZ_LT827010.1|WP_043513083.1|8792462_8792969_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_LT827010.1|WP_043513081.1|8781371_8782019_-|metal-dependent-phosphohydrolase	unknown	unknown	gnl|CDD|226789
NZ_LT827010.1|WP_014694924.1|8793628_8794912_-|threonine-synthase	unknown	unknown	gnl|CDD|236065
NZ_LT827010.1|WP_014694911.1|8779877_8780726_+|sulfurtransferase	unknown	unknown	gnl|CDD|225450
NZ_LT827010.1|WP_080128154.1|8789876_8790347_-|peroxiredoxin	unknown	unknown	gnl|CDD|239315
NZ_LT827010.1|WP_099343956.1|8782064_8783186_+|FUSC-family-protein	unknown	unknown	gnl|CDD|226614
NZ_LT827010.1|WP_014694923.1|8792968_8793412_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014694918.1|8787535_8787823_-|DUF4031-domain-containing-protein	unknown	unknown	gnl|CDD|379076
NZ_LT827010.1|WP_080128153.1|8785578_8786922_+|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NZ_LT827010.1|WP_172898946.1|8780722_8781067_+|DUF1416-domain-containing-protein	unknown	unknown	gnl|CDD|377793
NZ_LT827010.1|WP_099344242.1|8783537_8785187_+|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|379143

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_172898947.1|8785177_8785474_-|co-chaperone-GroES	gnl|CDD|197951	smart00883, Cpn10, Chaperonin 10 Kd subunit. The chaperonins are 'helper' molecules required for correct folding and subsequent assembly of some proteins. These are required for normal cell growth, and are stress-induced, acting to stabilise or protect disassembled polypeptides under heat-shock conditions. Type I chaperonins present in eubacteria, mitochondria and chloroplasts require the concerted action of 2 proteins, chaperonin 60 (cpn60) and chaperonin 10 (cpn10). The 10 kDa chaperonin (cpn10 - or groES in bacteria) exists as a ring-shaped oligomer of between six to eight identical subunits, while the 60 kDa chaperonin (cpn60 - or groEL in bacteria) forms a structure comprising 2 stacked rings, each ring containing 7 identical subunits. These ring structures assemble by self-stimulation in the presence of Mg2+-ATP. The central cavity of the cylindrical cpn60 tetradecamer provides as isolated environment for protein folding whilst cpn-10 binds to cpn-60 and synchronizes the release of the folded protein in an Mg2+-ATP dependent manner. The binding of cpn10 to cpn60 inhibits the weak ATPase activity of cpn60.	4.81939e-23
NZ_LT827010.1|WP_014694924.1|8793628_8794912_-|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NZ_LT827010.1|WP_014694926.1|8796136_8798842_-|alpha/beta-fold-hydrolase	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.04424e-84
NZ_LT827010.1|WP_043516383.1|8798972_8801132_+|AAA-family-ATPase	gnl|CDD|273521	TIGR01243, Cell_division_cycle_protein_48_homolog_MJ1156, AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.	1.78581e-149
NZ_LT827010.1|WP_014694908.1|8776697_8777414_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.53551e-43
NZ_LT827010.1|WP_099344241.1|8778726_8779554_+|DUF2993-domain-containing-protein	gnl|CDD|378597	pfam11209, DUF2993, Protein of unknown function (DUF2993). This family of proteins with unknown function appears to be restricted to Cyanobacteria.	8.84427e-19
NZ_LT827010.1|WP_014694925.1|8795264_8796140_-|ABC-transporter-permease-subunit	gnl|CDD|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	3.59314e-05
NZ_LT827010.1|WP_014694921.1|8790453_8792076_-|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NZ_LT827010.1|WP_043513083.1|8792462_8792969_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.20765e-11
NZ_LT827010.1|WP_043513081.1|8781371_8782019_-|metal-dependent-phosphohydrolase	gnl|CDD|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	3.03356e-40
NZ_LT827010.1|WP_014694928.1|8801134_8801458_-|DUF3263-domain-containing-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	7.64206e-34
NZ_LT827010.1|WP_014694911.1|8779877_8780726_+|sulfurtransferase	gnl|CDD|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	3.12324e-103
NZ_LT827010.1|WP_080128154.1|8789876_8790347_-|peroxiredoxin	gnl|CDD|239315	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The protein was named BCP based on its electrophoretic mobility before its function was known. BCP shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides. BCP contains the peroxidatic cysteine but appears not to possess a resolving cysteine (some sequences, not all, contain a second cysteine but its role is still unknown). Unlike other PRXs, BCP exists as a monomer. The plant homolog of BCP is PRX Q, which is expressed only in leaves and is cellularly localized in the chloroplasts and the guard cells of stomata. Also included in this subfamily is the fungal nuclear protein, Dot5p (for disrupter of telomere silencing protein 5), which functions as an alkyl-hydroperoxide reductase during post-diauxic growth.	2.74925e-26
NZ_LT827010.1|WP_099343956.1|8782064_8783186_+|FUSC-family-protein	gnl|CDD|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	8.78747e-25
NZ_LT827010.1|WP_014694918.1|8787535_8787823_-|DUF4031-domain-containing-protein	gnl|CDD|379076	pfam13223, DUF4031, Protein of unknown function (DUF4031). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 91 and 130 amino acids in length. There is a conserved HYD sequence motif.	8.03149e-28
NZ_LT827010.1|WP_080128153.1|8785578_8786922_+|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	4.00243e-57
NZ_LT827010.1|WP_172898946.1|8780722_8781067_+|DUF1416-domain-containing-protein	gnl|CDD|377793	pfam07210, DUF1416, Protein of unknown function (DUF1416). This family consists of several hypothetical bacterial proteins of around 100 residues in length. Members of this family appear to be Actinomycete specific. The function of this family is unknown.	7.73006e-45
NZ_LT827010.1|WP_099344242.1|8783537_8785187_+|PrsW-family-intramembrane-metalloprotease	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	2.6373e-46

Protein sequences

>NZ_LT827010.1|WP_080128153.1|8785578_8786922_+|AI-2E-family-transporter
MGRGVTVVGRAHYRDGRVTRIRRGGRRLNRLQRVRENLRKAYDTGREAARVTRIDRPRPEPEPEEDDFVAVPAEPAVVHGSTTSLDDVDVPHSLRIAAAWSWRLIVVGLVGYAGLRFISQVDVVVIPLAIALLLTALLGPAVGWLRKLHLPRSLATFLVLVGGLGAVAGTLTLVVNQFIDGLPQLTEKATAGVRQIQDWAKTGPLHLSDKQVDRAIDSAQSWVNDNTSSLTSTGISTAATVFELLTGLLLVLFSTFFFLRDGHKIWRFIVRLFPVSARWSLADAGDASWATLGAYVRATVLVAFIDAVGIGLALLILDVQFPFPLAALVFLGAFVPIVGAGVSGAVAVLVALVGQGWVVALITLGAVILVQQLEGHVLQPLIMGRAVAIHPLAVIIGIACGVVLAGITGALVAVPLIAVLNTGIRRLSRRRPEIPPDAIVVTAGHPS
>NZ_LT827010.1|WP_172898947.1|8785177_8785474_-|co-chaperone-GroES
MLHDRVLVRQDGGEGERRSTAGIVIPATASMGRRLSWAVAVGVGPNVRSIVVGDRVLFDPDDRSEVELHGKGYVLLRERDVHAVAATRVESDGTGLYL
>NZ_LT827010.1|WP_099344242.1|8783537_8785187_+|PrsW-family-intramembrane-metalloprotease
MVQTVAPIPGRRAGWRRWVPVTGVIVLIAAAAIGMLIFLGYSIGIAGLAVGLTAAILPVPLLASAFAWLDRYEPEPVKYLIFCFAWGAAVATAVALAVNTGASWLFDKIGLPDALVAVLVAPFIEESMKALGPVLLFWRRRAEWSGITDGIVYCGLSALGFAMVENVLYLGGHGYAAGAQQYGPATGLTNVFLIFIVRILFTGFAHPLFTSMTGIGLGISSRSADKHVRWLAPVGGWLLAMILHGTFNLLPTLSAATGKSLIMLYGYLGFMVPFFFAVVGFAIALRSWEGRLAERVLHHYVHTGWFAPPEVAALGSLGRRHSARQWAKRVAGPAGNRAMRSFQFAATRLAIIRDGMQRGLNGDQKEMTKAVLEERELLAAIVGYRAVFAGRDPQTPPAWWDGQAYRITFPDGVVRTVTAPAEPVMPVPVRLPPPMPAYAGGWGQPSPGYPGGPGYPGGPGHPGAQGPYGTPGYGAPGHGAPGYGAPGYGAPGYGAPGYGPPPFAPPPSGYGPPAAYGPPSSAPPHSAPPHSAPPASGPPQYPGQYPPYR
>NZ_LT827010.1|WP_099343956.1|8782064_8783186_+|FUSC-family-protein
MRAATARARAGLMLAVQAGLAAGLAWYVAHHLIGRPAPFFAPVAAVITLASSVGQRVRRTAELVAGVAVGIGVGDGIILLIGTGPVQIGLIVILAVLVATAAGGGSPLIVQSASSAVLVATLTVQTGHPWTRFFDALVGGGIGLTVMTVLLPLNPLSVVRRAADPALRAFTAGLHEAALGLAEGDPDVIEAALSRLRAAEATFANFRTAIDAARENVAFAPARWRNRGALAQYVDGAAQLTYALRNVRVMIRRAQTALNDRERVPEVLPASVRHLGDAVDLLRQEWARGVPPVAARERALRAAAESGRAYDTGVGYSGGVVVAQIRTAVADLLRATGVEYAEATLQVRAAVGWSGRAQGARNRTGRSRHPGLG
>NZ_LT827010.1|WP_043513081.1|8781371_8782019_-|metal-dependent-phosphohydrolase
MTTVTSLPDRFRAAARGAGATAADADLDSAANYLLTRWTEPQRHYHDVTHLAAVLEVIDEFAGLAPHPDRVRLAAWMHDAVYDPRALGDANERDSAEFAAGLLVTLGAPEEVAAEVARLVGLTAGHATEENDPDGELLCDADLAILAADEERYARYCAAIRREYAHVPDGDFRAGRSRVLTELLKLPSIYRLAPIRDAWEARAQANLKAELEALA
>NZ_LT827010.1|WP_172898946.1|8780722_8781067_+|DUF1416-domain-containing-protein
MITMTSPVANAAASCAAPDQSAPLPASVDLEKETVITGIVRTAEGEAVGGAYVRLLDGSGEFTAEVVTSPEGVFRFFAAPGSWTLRALSRFGNGELAVDATRGVNEVSFSVATA
>NZ_LT827010.1|WP_014694911.1|8779877_8780726_+|sulfurtransferase
MSRDNALVSADWAEKNLDTPGIVFVEVDEDTTAYDGGHIPGAIKIDWKQDLQDPVRRDFVNQEQFSALLSERGISNDDTVILYGGNNNWFAAYAFWYFKLYGHESVKLLDGGRKKWELDARVYTKDAPSRAQTSYQAKAPNLEIRAFRDEVVQAIGVKNLVDVRSPDEFAGRLLAPAHLPQEQSQRAGHIPTAISVPWSKAANEDGTFKSDEELAKIYGDAGLDGSKDTIAYCRIGERSSHTWFVLKELLGQQNVKNYDGSWTEYGSLIGVPIALGDEPGKA
>NZ_LT827010.1|WP_099344241.1|8778726_8779554_+|DUF2993-domain-containing-protein
MYGPQQFTNREGPVAEVYETAPRRRRRGRGVLIILVILLVIVLGVAFVVDRFGRSFAEGVISDKVAGQIRAQKASSDTPDVTIEGFPFVTQVLDGHYQEIHIEVPHLTAPVDKTRKINLALLDIHAQDVKASLDTLRNGSGDVVVGTVTGVSTIDYPQLVELIGQKGVKLSAKDGKLIGAATVTALGQQVDLTGAAKLTVVDGGIRVRFSDVRATNLPNVPLIQNLIDAQAQRMSLDLAVPKLPLQLRVQSVAAGDDGLKVQFGAQNVNLNAGGL
>NZ_LT827010.1|WP_043513080.1|8777693_8778692_+|hypothetical-protein
MPQDDPWDADASRDVARLNPGRPKAGMYGAVPDDEPDERPTSEPGDDFDDEFEEIEVVPVRRKLSVAIGGFAALLALALILGTLTTGPGVRTPYAIVLFGIQLLGLLAWTMALSPPAASLTAAASGLTGLVACYLAATADTAGLTPLLYVTGGGFVAALAAQAVRAEDRHRIGDSWRTTLLIVAGVVAYAIPIVLSRQSLGSQAILVCCAGAGLAVLVARLADAVFPKPRIAPQVPRGAAGVVLGAMAGTFFTAWLGSQLVYPFNPAKGAVTGLVAAVAAILVDLAVNFGEAGRRLAGEAPTLWLARHMTGPLGGFALTFVATYLLVHLYLT
>NZ_LT827010.1|WP_014694908.1|8776697_8777414_-|response-regulator-transcription-factor
MEILLLVTARAGEPSAVLPALDLLPHSVRTAPRDVRTLVSGPSPDAVLVDARSELSEARATCRMLHATGIGVPLIAVVTEAGLIALNADWGVDDVILASAGPAEVEARLRLSVGRLTNATAGAGGSIRAGELNIDPDTYAAKLKGRPLDLTYKEFELLKFLAQHPGRVFTRDQLLREVWGYDYFGGTRTVDVHVRRLRAKLGSEYESMIGTVRQVGYKFVVPPSGRQLPDNAPVSLPV
>NZ_LT827010.1|WP_014694918.1|8787535_8787823_-|DUF4031-domain-containing-protein
MILVDEPRWPGRGHLWSHLVSDVSYAELHAFAEMLGSPRRAFDRDHYDIPAARFRAALWLGATLVPPRELTARLRAANLRRPKHLAGGSLRTASR
>NZ_LT827010.1|WP_080128154.1|8789876_8790347_-|peroxiredoxin
MIGEIAVHAPKISFPGAFAPESHGYPPRWAEIPGTRGCTLEALTYAGRADRFAAAGARIRGVSTQRADQLRAFAAHAALPYELLSDADGRLATALRLPTFRAGGGDRLKRLTMLIDPAGTIRDVRFPVTDPAASVDEMLDLLGGYSSGAGHIPPPG
>NZ_LT827010.1|WP_014694921.1|8790453_8792076_-|chaperonin-GroEL
MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDTFEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPMALKRGIEAAVASVSEGLQQLAKDVETKEQIASTASISAGDSTVGEIIAEAMDKVGKEGVITVEESNTFGLELELTEGMRFDKGYISAYFMTDAERMEAVFDDPYILIANSKISNVKDLLPILEKVMQSGKPLVIIAEDVEGEALATLVVNKVRGTFKSVAVKAPGFGDRRKAMLEDIAILTGGAVISEEVGLKLDAADLSLLGQARKVVITKDETTVVDGAGNGEQIQGRVNQIRAEIERSDSDYDREKLQERLAKLAGGVAVIKVGAATEVELKERKHRIEDAVRNAKAAVEEGIVPGGGVALVQAGKTAFDKLDLVGDEATGANIVKVALDAPLRQIAVNAGLEGGVVVEKVRNLEAGHGLNAATGEYVDLLAAGIIDPAKVTRSALQNAASIAALFLTTEAVVADKPEKNPAPAGAPGGGDMDF
>NZ_LT827010.1|WP_043513083.1|8792462_8792969_+|GNAT-family-N-acetyltransferase
MESWMVRRITARDAGRMRALRLEMLADSPLAFLETLAQAAARSHEGYRRRLDMAADGPELAQFVTDPGDGPLLGHAGGTAIPDDPLVTVVFSVYLTPAARGGKMLASLIEAIADWSTAAGRHELMLEVVTGNDRAVRAYEKLGFQDTGVRLPHPTVPVLTELQMRRRL
>NZ_LT827010.1|WP_014694923.1|8792968_8793412_+|hypothetical-protein
MAGRWHVARTLLTAVNGTTGAGLLLALITRTRVRRGRDGVLIAEGWRLPMPPASCFTVGSVIITRRSAEWLLAEERAALLAHESRHAGQYAVLGPLFWPAYWVACGWSFTATGSYGVRNFFERHAGLKDGGYPEDLPLRPWLQRLKR
>NZ_LT827010.1|WP_014694924.1|8793628_8794912_-|threonine-synthase
MTSTVSAPAAISTSPARGLVCRACGAQYPLAAQHACYECFGPLEVAYDEAALARVTRAEIEAGPQNIWRYAALLPAGQDPATRVTLDPGLTPLVSAPQLAAELGITAPLWVKDDSQNPTHSFKDRVVSVALTAAKELGFTRFSCASTGNLANSVAAHAARAGVPSIVFIPGDLEQGKVVMSAIYGGDLVAIDGSYDDVNRLCSELVETDEFEDTAFVNVNVRPFYAEGSKTLGYEVAEQLGWRIPAQVVIPMASGELLTKVDKAFSELVEIGLAEAPEGGWRVFGAQSQGCNPIAVALHGDTDVITPVKPTGIAKSLNIGDPAAGPYAIEAVRRTGGWMDYADDDEIRAGISLLARTTGVFAETAGGTTVAVLKKLVESGRLDPTRETVVYNTGEGLKTLDAIVGTAGPTHRIKPSLRGAREAGLLG
>NZ_LT827010.1|WP_014694925.1|8795264_8796140_-|ABC-transporter-permease-subunit
MSIDVSPDAAAGYRPSRTLPIVAEIRRQASRRRTQLALGFMVLLPLIILVAFEFGSDNRGDDDNGGGAFSSLVDLATSGGLNFALFCLAVSAGFLLVVVFALFAGDTVASEASWGSLRYLLAIPVPRARLLAVKLVVALGYAFLALFLLAGTGLLVGTLRYGWHPLGSTIAARIPPGQGVLRLLAILAYLAVILLVVAGLAFLLSVLTDAALGAVGGAVLLWILSSILDQITALGSIRTGLPTHYSDAWLGLLSTPVQTEDLAKGAISAIIYATLFWGTAFLRFTRKDVTS
>NZ_LT827010.1|WP_014694926.1|8796136_8798842_-|alpha/beta-fold-hydrolase
MSALPRVTRRRAVTAAVVLVLLAAATVWAVLPARAAWTAQDLRIPVRTGPAGDQQVELDARFLLPRDRSGTVPAVLLAHGFGGSRDSVRSDAESLAARGYAVLTWTAQGFGRSTGEIHLDSPDYEVKDARQLLDWLAARPEVRTDAPGDPRVGVVGGSYGGALALLLAGQDPRVDAIVPSITWNDLDHAFLPQSAATDATGVFKKGWAGVFFGSSAGGDNPACGRFAADVCAAYLSMATSGTPDAAALALLRRSSPATVLDRIKAPTLLIQGAVDTLFPLSEADANAKGIAATGTPVRVAWFTGGHDGGAGPRSDQDRVEYLTGQWLDHYLKGRGAAPGDDFTFSRVAGFSAMDRDLVTNGYSTDSYPGTTGTGSTRVAVTGAAQPIANPPNGNPAALSALPGLGSRLSSLLSGNLSADIPGQHATFASAPLTAAVDVAGAPTIRLRAASPTGSATLFVKLYDVDQSGAPTLSAGLVAPVRLTGLPTGIEQAQPVTVTLPAIVRRMEAGHTLQVVVATSDQAFLSPPGPATYTVAVDGQLTLPTLVGTPIATPAALWWYALAALIAVILIALAVLSVIRRARRRRRVTAVRDDLADTPLVVTGLRKAYKDGFVAVEEIGFTVERGQVVGLLGPNGAGKTTTLRVLMGLTTPTAGEIHVFGHRLVPGAQVLSRVGALVEGPGFLPHLTGEQNLRAYWQATGRPWADARFEEALEIAGLGASIHRRTKNYSHGMRQRLAIAQAMLGLPELLVLDEPTDGLDPPQIAEMRRVLQRYATDGRAVLVSSHLLAEVEQTCTHAVVVNKGRIVASGPVGDIVGESPSVAFEVSDVPAATAILSGLGVRSVTPDGATGLIVEMNGTPRADLVASLVKAGVGVDRVVPRRRLEDAFLALVGDNSRGSGDR
>NZ_LT827010.1|WP_043516383.1|8798972_8801132_+|AAA-family-ATPase
MTWRSPADEGRRALVRMHPTAMKALELEPGQAARLSGSRSTVVRVIADETTGQKQLHADDLTFGNAGVPDGGPVTVTPIPLTAASRVILSGPPGVHGTIPPEMLRQALFGKTVSPGDDVSLLSQEVFPDRKPPVSPSTRSSLSSRFPWWTNQLLTVESVDDGVLVTTKTVVGWQDGPATATAREAAPETPAAGTPAEVPPPSLEDLVGLRAQAKELQELLDLGFNHREVLAKLHTRVALGILVSGPSGSGKGGMVRAVAATVGAEVRLIWAPELAALTNDAAARRLREAAAAIRGDKPAVLLVSDVEALAPRDEPGPIATVFRQVLAELVAGGAAVVCTTGRPESVDPELRAPDLLAVQLTVPLPDAAMRREQLTVLTRGMPLAADVRLDDVAGRTPGYVAADLGALVREAGVRAALRQKTSDEPSVTMADFEAALDVVRPTSMAESTLEVATVTLDDVGDMAEVKQVLTESVLWPLTYPDTFARLGVTPPRGVLLYGPPGCGKTYLVKAIAGTGKANVLSVKGAELLSKWVGDSEKAVRELFRRAREAAPTLVFLDEVDALAPARGQGSDGGVTDRVVAALLTELDGVEDLRNVVVIGATNRPDLIDPALLRPGRLERLVYVPPPDGPARAAILRASAKSVPLDESVDLTALGEELTGFSAADCSALIREAALAAMRGSLEASTVTAANVSTARERVRASLDAAQVAWLESYAEKRNA
>NZ_LT827010.1|WP_014694928.1|8801134_8801458_-|DUF3263-domain-containing-protein
MQPAAEPTGDQQHIPAPRTAEPSGQPEVAEQPALSEREEQILAFEAKWWKHAGAKEQAIRDTFDLSSTRYYQLLNGLLDNPAALERDPVLIGRLRRLRSTRARTRRR

Crispr_ID: NZ_LT827010_23

• CRISPR_ID: NZ_LT827010_23
• CRISPR_location: 8984669-8984843
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT827010_23

Consensus_repeat	Method
GCCTCGGCGGAGCCGGCCTGGAACACCCCGGCTCCGGCCG	PILER-CR

spacers of NZ_LT827010_23

>23.1|8984709|32|NZ_LT827010|PILER-CR
CCCCGGCACCGGCCTGGAACACCCCGGCCGCC
>23.2|8984781|27|NZ_LT827010|PILER-CR
AGACCCACTGGAACAGCCCGCAACAGC

CRISPR arrays and Neighbor proteins around NZ_LT827010_23

CRISPR arrays

The CRISPR arrays of NZ_LT827010_23

>merge|NZ_LT827010|23|8984669-8984843|PILER-CR
GCCTCGCCGTCGCCGGCCTGGAACACCCCGGCCCCGGCCTCCCCGGCACCGGCCTGGAACACCCCGGCCGCCGCCTCGGCGGAGCCGGCCTGGAACACCCCGGCTCCGGCCGAGACCCACTGGAACAGCCCGCAACAGCCGGCGGAGCCGGCCTGGAACACCCCGGCTCCGGCCG

>NZ_LT827010|23|3|8984669-8984843|PILER-CR
GCCTCGCCGTCGCCGGCCTGGAACACCCCGGCCCCGGCCT	CCCCGGCACCGGCCTGGAACACCCCGGCCGCC
GCCTCGGCGGAGCCGGCCTGGAACACCCCGGCTCCGGCCG	AGACCCACTGGAACAGCCCGCAACAGC
CGGCGGAGCCGGCCTGGAACACCCCGGCTCCGGCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_085945619.1|8972726_8973347_+|M23-family-metallopeptidase	unknown	unknown	gnl|CDD|366703
NZ_LT827010.1|WP_043513136.1|8981058_8982171_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014695089.1|8990491_8992123_+|DUF2334-domain-containing-protein	unknown	unknown	gnl|CDD|200549
NZ_LT827010.1|WP_014695086.1|8987154_8987727_+|hypothetical-protein	unknown	unknown	gnl|CDD|235124
NZ_LT827010.1|WP_014695087.1|8987916_8989248_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133058
NZ_LT827010.1|WP_014695075.1|8973358_8974300_+|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|235824
NZ_LT827010.1|WP_014695083.1|8985564_8986011_+|roadblock/LC7-domain-containing-protein	unknown	unknown	gnl|CDD|224929
NZ_LT827010.1|WP_014695090.1|8992132_8992483_+|hypothetical-protein	unknown	unknown	gnl|CDD|341462
NZ_LT827010.1|WP_014695080.1|8978931_8980602_+|DUF885-domain-containing-protein	unknown	unknown	gnl|CDD|377577
NZ_LT827010.1|WP_014695084.1|8986007_8986475_+|DUF742-domain-containing-protein	unknown	unknown	gnl|CDD|283084
NZ_LT827010.1|WP_014695077.1|8974907_8975870_-|S-methyl-5-thioribose-1-phosphate-isomerase	unknown	unknown	gnl|CDD|235578
NZ_LT827010.1|WP_043513132.1|8972057_8972261_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014695076.1|8974341_8974911_+|DinB-family-protein	unknown	unknown	gnl|CDD|368218
NZ_LT827010.1|WP_014695091.1|8992479_8993226_-|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NZ_LT827010.1|WP_014695079.1|8977829_8978888_+|PHP-domain-containing-protein	unknown	unknown	gnl|CDD|236135
NZ_LT827010.1|WP_014695088.1|8989307_8990492_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl|CDD|223458
NZ_LT827010.1|WP_014695073.1|8972349_8972679_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014695085.1|8986452_8987082_+|ATP/GTP-binding-protein	unknown	unknown	gnl|CDD|225138
NZ_LT827010.1|WP_014695078.1|8975880_8977734_-|M48-family-metalloprotease	unknown	unknown	gnl|CDD|320687
NZ_LT827010.1|WP_014695092.1|8993316_8993874_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|366102

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_085945619.1|8972726_8973347_+|M23-family-metallopeptidase	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.57526e-12
NZ_LT827010.1|WP_014695089.1|8990491_8992123_+|DUF2334-domain-containing-protein	gnl|CDD|200549	cd10923, CE4_COG5298, Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria. This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily. Some family members contain an additional copper amine oxidase N-terminal domain.	3.9639e-76
NZ_LT827010.1|WP_014695086.1|8987154_8987727_+|hypothetical-protein	gnl|CDD|235124	PRK03427, PRK03427, cell division protein ZipA; Provisional.	0.00365133
NZ_LT827010.1|WP_014695087.1|8987916_8989248_+|glycosyltransferase-family-2-protein	gnl|CDD|133058	cd06436, GlcNAc-1-P_transferase, N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine. N-acetyl-glucosamine transferase is responsible for the synthesis of bacteria Poly-beta-1,6-N-acetyl-D-glucosamine (PGA). Poly-beta-1,6-N-acetyl-D-glucosamine is a homopolymer that serves as an adhesion for the maintenance of biofilm structural stability in diverse eubacteria. N-acetyl-glucosamine transferase is the product of gene pgaC. Genetic analysis indicated that all four genes of the pgaABCD locus were required for the PGA production, pgaC being a glycosyltransferase.	1.61049e-58
NZ_LT827010.1|WP_014695075.1|8973358_8974300_+|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	gnl|CDD|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	8.79825e-81
NZ_LT827010.1|WP_014695083.1|8985564_8986011_+|roadblock/LC7-domain-containing-protein	gnl|CDD|224929	COG2018, COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid [General function prediction only].	2.15422e-14
NZ_LT827010.1|WP_014695090.1|8992132_8992483_+|hypothetical-protein	gnl|CDD|341462	cd08183, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) which catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions. The protein structure represents a dehydroquinate synthase-like fold and is a member of the iron-activated alcohol dehydrogenase-like family. It is distinct from other alcohol dehydrogenases which contain different protein domains. Proteins of this family have not been characterized.	0.00992345
NZ_LT827010.1|WP_014695080.1|8978931_8980602_+|DUF885-domain-containing-protein	gnl|CDD|377577	pfam05960, DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins.	1.58356e-177
NZ_LT827010.1|WP_014695084.1|8986007_8986475_+|DUF742-domain-containing-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	8.68265e-19
NZ_LT827010.1|WP_014695077.1|8974907_8975870_-|S-methyl-5-thioribose-1-phosphate-isomerase	gnl|CDD|235578	PRK05720, mtnA, methylthioribose-1-phosphate isomerase; Reviewed.	1.26127e-109
NZ_LT827010.1|WP_014695092.1|8993316_8993874_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.48732e-10
NZ_LT827010.1|WP_014695076.1|8974341_8974911_+|DinB-family-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	1.99129e-43
NZ_LT827010.1|WP_014695091.1|8992479_8993226_-|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	9.95389e-46
NZ_LT827010.1|WP_014695079.1|8977829_8978888_+|PHP-domain-containing-protein	gnl|CDD|236135	PRK07945, PRK07945, PHP domain-containing protein.	0
NZ_LT827010.1|WP_014695088.1|8989307_8990492_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl|CDD|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	4.53494e-123
NZ_LT827010.1|WP_014695085.1|8986452_8987082_+|ATP/GTP-binding-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	7.17047e-39
NZ_LT827010.1|WP_014695078.1|8975880_8977734_-|M48-family-metalloprotease	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	1.52619e-32

Protein sequences

>NZ_LT827010.1|WP_043513136.1|8981058_8982171_+|hypothetical-protein
MLLTALVLLPAAGLFLRVLQENSQQRDTVQLEQDGVEYLTVLGPLVSALAESQASALQGVAAEPASVTAAVARVQGVDGRLGDALETHSRWSDLKDKIAKLPKVTGTSEQIFTAHVEAADLAVELFDVVRENSRLNRDPEADVSFLQEVVGQLMPEAVTFVSRMSDYANMVPAARTKADKAKLTVQFGYQALKVQETVAKLTDSLQEAVESTKSTTLSGNLVSNLDSFRRGIEAANRGANIGGAPNVSTLVTAQSTLQTALSALSGVVLKEMSGRLDDRSSSLTYKRIEAFGLLGIAIVLIVVATLWTRGRARQVQATLVEPGQGSRDVSVRAGTSVPAGNPTGSPYDSIPNYGDTPNYGGGRERSGALR
>NZ_LT827010.1|WP_014695080.1|8978931_8980602_+|DUF885-domain-containing-protein
MGRIDELANRYVDEWAALNPTGATAAGITGHDDQTDDLSPEGFAARAELVRRTLNDLDVNEPEHETEQVAKEAMQERLGLELARLDSGIAATEVNVITSALHELRMVLDLMPAEGEQAVANIVTRLAAFPQALRQYRRTLLEGADRGVVSPSVQLAAVADQCAAWADPDRDGFFHGLAGRLQASGGLAEDLRRGAAAATAATADFGRFLREELAPRGRAKEAAGLERYTLASQYFLGAKVDLLETYHWGFEELHRLTREMQAVAAVIAGPGASVDEAVAALNADPARIIPDKERFRDWMQALSDRAVSELNGTHFDIEPPAQKLECCLTPTSDGGIYYTGPSEDFARPGRMWWAVPAGQQVFSTWQEVTTVYHEGVPGHHLQVSQTLLRADQLNRWRRLLAWCSGHGEGWALYAERLMDELGYLTDPGDRLGMLDSQALRATRVIIDIGMHLELEIPRDNPFGFHPGSRWTPELGWEFLRAHSRMQEDVLRFEWKRYLGWPGQAPSYKIGERIWLQARAEAKQRKGADFDLKAFHRDALDLGPLGLDPLRRALGRI
>NZ_LT827010.1|WP_014695079.1|8977829_8978888_+|PHP-domain-containing-protein
MASRDPVTDLRRIAFLLERANEATYRVKAFRSAAAAVARTPGDELTERAAAGTLAKLAGVGEVTARCVTESLAGEEPVYLRRLLSIEGADLPAAAAALREALRGDLHVHSDWSDGGSPIEEMALAAADLGHEYFVLTDHSPRLTVAHGLTAERLRRQLDHVAALNAQLPDGFRILTGIEVDILEDGSLDQEDELLARLDVVVASVHSRLRDDTARMTRRMLTAIANPHLDVLGHMTGRKVAAAGAGDAAHRTARTRPPSTFDLEKVLAACVEHDKAVEINSRPDRLDPPKRMLTVAVEAGCRFSIDTDAHAPGQLDWLGNGCERAALCGVPADRVVNTWPAERLLAWAAAHG
>NZ_LT827010.1|WP_014695078.1|8975880_8977734_-|M48-family-metalloprotease
MPTALRAAVSVVMLAGFYLLGLAQLVLVGWLIFEIWQHLHGAGAVKLSYLLLAAVGAVLAGLWRAIRAKPGHPHGLIVTPDQTPELWHQVRQLAAEAGTRAPDEIRLVPEVNAAVDEETRLLGLIGGTRRLYIGMPLVQTFTVDQLRSVLAHELGHYSGSHTRLSAVTYRGRLAMHETLSNVGSFNVFGWVFKAYAWLYQLVSSAVARRQELEADLASVRVAGVDAAVSAMRELPVVDAAWDFYFGRYIGYGWELGYAPDDVFGGFAQLYQARADELAEMREAEPDDETSRWDSHPALSERIAAMRAAPRTSHVTDGRPAAVLVPAVELAGMALQREVVDFGTRTVLPWADFTAASMAMRSQNRADRVFRSTARHAGVPEAGLPEVFGLVEAGRLADLATEFFPQATRREAVAEFADVMETLLGLAAVRSGTARWQHSWSGPARLVDQTGQVLDLGEIAKLAVVPETLAEARARLAERGVHVEAARVVEAKATGQGADVLGAVPNVKLDGGEHADLIVLDRGLIFVPAPKSTDDGDKRVGVLVAQNSAADLAARYRYVAYEEVSTVRIEKETPIGATLLLHDGRTVTFQERWSSDRMGRSVDVLRKILGELQERADR
>NZ_LT827010.1|WP_014695077.1|8974907_8975870_-|S-methyl-5-thioribose-1-phosphate-isomerase
MRTIDWVDGAVEIIDQTALPGELRVLRLHTVGELIAAIQSLAVRGAPALGVAGALGVALAAQVHADDPGALANAVRRIETARPTAVNLARGAQRAAARLPFGPAAVLAEACVLRDEEIAASAAQASRGADLVAELCGDRPRLLTHCNTGGLAAVTVGTALGVIGELHRRGTLGGVIASETRPLLQGARLTAWELGQWGVEHRVAVDSAGPFLMARGEVDAVILGADRICANGDVINKIGTYAHALGARRAGLPFLVVAPETTVDTGTPSGADVEIEDRGAAEVTAWSDAVNPAFDVTPHDLVTAIVTDRRVIRLDRGEKP
>NZ_LT827010.1|WP_014695076.1|8974341_8974911_+|DinB-family-protein
MPGQVGPISGEQDGLLSFLTQARYTLKLTAYGLTPEQLRATASASSLSIGGLIKHCVSTEEGWIATATGASQKPDFAAYHENFVLTGDETVEELFARYDRAAERTEKAVAELGLDHRIPVDHSVPWNRPDLDHFTTRWILLHLIQETARHAGHADIIRESIDGATAFPLMAAAEGWPETPWLKPWKKDS
>NZ_LT827010.1|WP_014695075.1|8973358_8974300_+|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein
MRIAVVGLGLIGGSLARALRDAGHEVSGFDTDPATRELARAAGLTVPGSVAATVAGTEVTVLAAPLPVLPGLVAELAGYDGVLTDVTSVKGPVQALAERHGVRRFVGGHPMAGTEASGFAAADPKLFEGCVWVLCVEPDGTDPADWLILAGLFTGLGARVLPITAVEHDNAVAAVSHVPHLLAAALATTLAGSPLRQALAAGSFRDGTRVAATRAELINAMCAGNATEVLRELQQVISDLVQLRDDLAGGDLIPFLAAAGELRRAWPPTPGSPGRTTADVRALLALGRGGGWVTAVVGTELNTMRPETGRNGF
>NZ_LT827010.1|WP_085945619.1|8972726_8973347_+|M23-family-metallopeptidase
MIVALGLAVAGATTASAAVTPRPAPAPAPRVVPAWMFTSKYTFPVAASNVAWHDTHSAYPATDIFAACGSTVVATDNGRVLEISLVDRFRKGMPDGPYNGGLFVSILGNDGVRYYGSHLSSVTKGIVPGALVKSGQQIGRVGHTGNANGVCHLHYAISPPCAQTGDWKVRRGVVWPYSFLASWRGNGQKSPVDTVAAWNKSHHCKA
>NZ_LT827010.1|WP_014695073.1|8972349_8972679_-|hypothetical-protein
MRVHGLYAGLPPRPIYREPHPIGAGPVLSGLAAGALWLLLFGSLGQDLTSYAWWTIGAAAAAWLVALVLTRLGDRGVALGVACSSGIGLSVAMGFVAFRWIETFNFPLW
>NZ_LT827010.1|WP_043513132.1|8972057_8972261_-|hypothetical-protein
MTNAARLGTLGTMATSPQRLDADRCRRRLELLAALAHAKSVRESAPPRRARGMRLRELIATRRRTTN
>NZ_LT827010.1|WP_014695083.1|8985564_8986011_+|roadblock/LC7-domain-containing-protein
MTSPYPTAQSQLSAEAKTFNWLLDSFTSGTAGVIEAIAVSSDGLLMAMSAIKDRPNAERLAAVVSGLTSLAGGAASWYRLGALNRVIIDMADGYLLVTAISAGSVLGVIADRSANLGTLAYEMTLFATRAGGALSPRLIAELKNAVQQ
>NZ_LT827010.1|WP_014695084.1|8986007_8986475_+|DUF742-domain-containing-protein
MTYPDPADEPVPPARSGVRPFLQSGPKHSAGGYTPTGEQPPVEPAQTNTLRPFVITAGRTDGGDPDIGMETQVAVVHGAPPSRLSPETRAIVSLLEESPISVAEISARLRLHLGVCQILVGDLRAAGQVDVQGRDTDTPDPETIMRVIRGLRSIS
>NZ_LT827010.1|WP_014695085.1|8986452_8987082_+|ATP/GTP-binding-protein
MDFDPSANRVVATARIPGGAAPAKKAPVPVKIIVAGGFGVGKTTTVGAISEIAPLTTEAEMTSESIGIDNVGQATTKTTTTIAMDFGVLTIDQTLKLYIFGTPGQTRFAFMWDDLVKGALGALVVVDTNRIDDCYPAVDYFERAGLPFVVGVNTFNGNMAYSLDEVRWALAVREDVPVISYDARFRASVRDALLVVLDQALDKAIKMKS
>NZ_LT827010.1|WP_014695086.1|8987154_8987727_+|hypothetical-protein
MRGGLDDALDKLARRDELRRRAAAGEAPGTPPAVTELVEAIAGVIARFPHLGVTVGVEGAGDPVLLHFGFADGTVQVTADRTVVERTAAEPARAHADIEIDLDDPEPPPRGSHDDQDRFGPTYDEPPTAERPFVTPPAPAYPPPPAAYAPPVEPAPQPKPFHAERAAEETEQAARRLAALLRDNPSLLDD
>NZ_LT827010.1|WP_014695087.1|8987916_8989248_+|glycosyltransferase-family-2-protein
MSASDGWLIAVAGYAILLAWPLSTVILVWFAVRYVGTHRARVVNQALASGDGRPEHFWIIVPALNEEAVVANTVTAALGLRGPARTLARVLVVDDGSDDRTPEVLAAIDHPRLHVMRRELPEARQGKGEALNAAYRFIARIAEQEGVPAERVVLGIIDGDGQGSDNILVEVGRLMGNTRVGAVQVQVRIRNRNKLLGAVQDLEFGAIVDACQNLRNSLDTVGLGGNGQFSRLSTLLSLGDTPWSSCLVEDMELGLRMHLKGVSIRYTSRASVTQQAVVDIKRLTRQRTRWAQGNIQCARYLGSLFASGNIARTALVEILHYLVSPWANAVVAMLLTLTGTAGALGLLIGHPVPILPSWFALGESLGIWAVVTTFPGLVWVLVHRVKRGDEELPRMLLAALAYPAFLLLGLTATYRALGRQLTGKQAWAKTERLVEEPLALKTA
>NZ_LT827010.1|WP_014695088.1|8989307_8990492_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MSLREVHLIGGTRPEAVKLAPVALAFREAGLLKPILLASGQHPTMVTQALAAFDLEPDITLTVERSTGTQAELLTAMIQQLDELWSVRTPAAVIVQGDTTTSLAGALAAFWRRIPVVHLEAGLRSGDLESPFPEEGNRRLVAQVAALHLAPTPLAAMNLLDEKIAASDVLITGNTVVDATLAVAARRLPYENPAVAAARAESTKRLVLVTAHRRESWGEPLDRILGAVNELLAKYPDIEVVLPSHPNPAVRAQVDAALAGAERVTVTDPLPYPDLARLLSEAYLVLTDSGGIQEEAPSFGVPALVLRDVTERVESLHAGCAKLVGSDPAVIVAEASALLDSRDRRDAMTAGGNPYGDGLAARRTAQATAALLGLATAPDAMPVRPSATEIGATA
>NZ_LT827010.1|WP_014695089.1|8990491_8992123_+|DUF2334-domain-containing-protein
MRAKKVTRRTLIAGGGAAAVAVATGVGINAVQADAASTAPATGSVITKSGRGGPGAGAAKTLVLYDTTGDYGWLGEVYATQTANLSSRFGSWTAAPVARYKAGDLSAYTAVIYLGSTYDEPLPAAFLTDVMATTKQVLWVYDNIWQLAAKDGFAAKYGFASGTFDFADVTEVDYKGRKLTRGTENKSGIMNLSIGDSAKVTTLATAVRADGTGFPWAVRSGNLTYVGEIPFAYVTHDDRYLAFADLLFDTLGGGTTERHRALIRIEDVGPDADPEQLTAVADFLFAEKVPFSVAVYPRFRDPKGVGTGKAQDYTLLNKPKVVAALKYMQARGGTLVMHGYTHQYGSVANPYDGVSANDFEFYKAHVDAGDNVVYDGPVAEDSAAWATGRMMSSGAVFLAAGLGSPRLFEFPHYAASAPDYEVVNALFGKRYDRGLYFPGVLTGARFDYSRQFGQFFPYPVRDVYGSLVVPENIGNVETEAFNNHPVRLPADIVASAQRNLVVRDGVASCFYHAYLGTDHLKDLIGGIKAAGYTFVSAESTLSA
>NZ_LT827010.1|WP_014695090.1|8992132_8992483_+|hypothetical-protein
MDVVDFWVRSWTSDDLAAARRVLSPHVEVEWNLDAPVDDEELLQVLHRIAVFADHVALTARTDALDGAALIYDLTAPFGSARLAEFLAVEDEKIVEIRHVYDVTAIDRYFPGLYAN
>NZ_LT827010.1|WP_014695091.1|8992479_8993226_-|dienelactone-hydrolase-family-protein
MQQTSIDIPAADGPADGYFVKPDGPGPYPGILIFMDGFGVRPRLREMADRIAERGYAVLLPNLLYRDQRSPLVDPAELADPEKRGAAFGRLMPMMQNLTAPRLVADVTAYLDFLAAQEGVAPGPVGAVGYCMGGRNGLIAMSALPDRIKVLGSFHAGRVVTGDEHSPHLGVGAITGEVYFGHADNDASMTPDQIKTLEAALDEAGVTYTSELYEGAPHGYTMSDTAMHHPAGEQRHWAALFDLLDRNF
>NZ_LT827010.1|WP_014695092.1|8993316_8993874_+|helix-turn-helix-transcriptional-regulator
MATRLRADARRNRAALLTAAREVFAEQGLDASLDEIARRAGVGNATLYRRFPSRRHLIAEVFAGHMTAAVRLADQALEHPDPWAAFIGYLSRVCELQATDRGLAELLVTDAFDDDERLSALRAAAQQRAVDVLTRAQRAGRLRADFTRHDLWLVMMANAGVNRHATEPHAWRRQLALLIGGLATR

Crispr_ID: NZ_LT827010_24

• CRISPR_ID: NZ_LT827010_24
• CRISPR_location: 9194884-9194955
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_24

Consensus_repeat	Method
GTTGTTGCCACCACCGTTGTTGTT	CRISPRCasFinder

spacers of NZ_LT827010_24

>24.1|9194908|24|NZ_LT827010|CRISPRCasFinder
ACCACCGTTGTTGTTGCCACCGCC

CRISPR arrays and Neighbor proteins around NZ_LT827010_24

CRISPR arrays

The CRISPR arrays of NZ_LT827010_24

>merge|NZ_LT827010|24|9194884-9194955|CRISPRCasFinder
GGTGTTGCCACCGCCGTTGTTGCCACCACCGTTGTTGTTGCCACCGCCGTTGTTGCCACCACCGTTGTTGTT

>NZ_LT827010|24|20|9194884-9194955|CRISPRCasFinder
GGTGTTGCCACCGCCGTTGTTGCC	ACCACCGTTGTTGTTGCCACCGCC
GTTGTTGCCACCACCGTTGTTGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_043513222.1|9200184_9201327_+|CapA-family-protein	unknown	unknown	gnl|CDD|378215
NZ_LT827010.1|WP_014448192.1|9186999_9187290_-|30S-ribosomal-protein-S6	unknown	unknown	gnl|CDD|179034
NZ_LT827010.1|WP_014695272.1|9185589_9186039_-|50S-ribosomal-protein-L9	unknown	unknown	gnl|CDD|234659
NZ_LT827010.1|WP_014695284.1|9203610_9204885_+|poly-gamma-glutamate-synthase-PgsB	unknown	unknown	gnl|CDD|188527
NZ_LT827010.1|WP_014695280.1|9198282_9198936_+|PadR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224609
NZ_LT827010.1|WP_155123732.1|9180112_9184774_+|hypothetical-protein	unknown	unknown	gnl|CDD|235906
NZ_LT827010.1|WP_043513213.1|9178269_9179703_-|replicative-DNA-helicase	unknown	unknown	gnl|CDD|273206
NZ_LT827010.1|WP_014695286.1|9205377_9206421_+|C40-family-peptidase	unknown	unknown	gnl|CDD|366353
NZ_LT827010.1|WP_014695283.1|9201406_9203608_+|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|381743
NZ_LT827010.1|WP_014695279.1|9197686_9198121_-|DUF5318-domain-containing-protein	unknown	unknown	gnl|CDD|379953
NZ_LT827010.1|WP_014695273.1|9186361_9186934_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|236092
NZ_LT827010.1|WP_014695274.1|9187586_9188552_-|hypothetical-protein	unknown	unknown	gnl|CDD|237082
NZ_LT827010.1|WP_014695277.1|9193154_9194672_-|DUF2029-domain-containing-protein	unknown	unknown	gnl|CDD|227937
NZ_LT827010.1|WP_007073789.1|9186053_9186293_-|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NZ_LT827010.1|WP_099344256.1|9177666_9177972_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|376829
NZ_LT827010.1|WP_014695275.1|9188682_9189456_+|deoxyribonuclease-IV	unknown	unknown	gnl|CDD|179214
NZ_LT827010.1|WP_014695288.1|9207409_9207865_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl|CDD|223427
NZ_LT827010.1|WP_014695285.1|9204881_9205367_+|poly-gamma-glutamate-biosynthesis-protein-PgsC/CapC	unknown	unknown	gnl|CDD|379469
NZ_LT827010.1|WP_099344257.1|9206437_9207196_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_043513219.1|9198959_9200039_+|inositol-3-phosphate-synthase	unknown	unknown	gnl|CDD|132491

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_043513222.1|9200184_9201327_+|CapA-family-protein	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	1.78953e-80
NZ_LT827010.1|WP_014448192.1|9186999_9187290_-|30S-ribosomal-protein-S6	gnl|CDD|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	2.83423e-40
NZ_LT827010.1|WP_014695272.1|9185589_9186039_-|50S-ribosomal-protein-L9	gnl|CDD|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	2.62861e-70
NZ_LT827010.1|WP_014695284.1|9203610_9204885_+|poly-gamma-glutamate-synthase-PgsB	gnl|CDD|188527	TIGR04012, poly_gGlu_PgsB, poly-gamma-glutamate synthase PgsB/CapB. Of four genes commonly found to be involved in biosynthesis and export of poly-gamma-glutamate, pgsB(capB) and pgsC(capC) are found to be involved in the synthesis per se. Members of this family are designated PgsB, a nomeclature that covers both cases in which the poly-gamma-glutamate is secreted and those in which it is retained to form capsular material.PgsB has been shown to have poly-gamma-glutamate activity by itself but is bound tightly by PgsC (TIGR04011). [Cell envelope, Other].	2.82994e-123
NZ_LT827010.1|WP_014695280.1|9198282_9198936_+|PadR-family-transcriptional-regulator	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.75165e-15
NZ_LT827010.1|WP_155123732.1|9180112_9184774_+|hypothetical-protein	gnl|CDD|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	1.4415e-08
NZ_LT827010.1|WP_043513213.1|9178269_9179703_-|replicative-DNA-helicase	gnl|CDD|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LT827010.1|WP_014695286.1|9205377_9206421_+|C40-family-peptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	4.94004e-05
NZ_LT827010.1|WP_014695283.1|9201406_9203608_+|HAMP-domain-containing-protein	gnl|CDD|381743	cd06225, HAMP, Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.	0.000109
NZ_LT827010.1|WP_014695279.1|9197686_9198121_-|DUF5318-domain-containing-protein	gnl|CDD|379953	pfam17249, DUF5318, Family of unknown function (DUF5318). This family of unknown function is mostly found in Actinobacteria.	1.46587e-84
NZ_LT827010.1|WP_014695273.1|9186361_9186934_-|single-stranded-DNA-binding-protein	gnl|CDD|236092	PRK07772, PRK07772, single-stranded DNA-binding protein; Provisional.	8.44915e-92
NZ_LT827010.1|WP_014695274.1|9187586_9188552_-|hypothetical-protein	gnl|CDD|237082	PRK12373, PRK12373, NADH-quinone oxidoreductase subunit E.	0.00648888
NZ_LT827010.1|WP_014695277.1|9193154_9194672_-|DUF2029-domain-containing-protein	gnl|CDD|227937	COG5650, COG5650, Predicted integral membrane protein [Function unknown].	1.53764e-32
NZ_LT827010.1|WP_007073789.1|9186053_9186293_-|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	1.91184e-33
NZ_LT827010.1|WP_099344256.1|9177666_9177972_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|376829	pfam02575, YbaB_DNA_bd, YbaB/EbfC DNA-binding family. This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure. The conformation of the DNA is changed when bound to these proteins. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage.	3.90962e-13
NZ_LT827010.1|WP_014695275.1|9188682_9189456_+|deoxyribonuclease-IV	gnl|CDD|179214	PRK01060, PRK01060, endonuclease IV; Provisional.	1.80915e-106
NZ_LT827010.1|WP_014695288.1|9207409_9207865_-|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl|CDD|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	3.7309e-47
NZ_LT827010.1|WP_014695285.1|9204881_9205367_+|poly-gamma-glutamate-biosynthesis-protein-PgsC/CapC	gnl|CDD|379469	pfam14102, Caps_synth_CapC, Capsule biosynthesis CapC. This family of proteins play a role in capsule biosynthesis. They are essential for gamma-polyglutamic acid (PGA) production.	2.00507e-26
NZ_LT827010.1|WP_043513219.1|9198959_9200039_+|inositol-3-phosphate-synthase	gnl|CDD|132491	TIGR03450, mycothiol_INO1, inositol 1-phosphate synthase, Actinobacterial type. This enzyme, inositol 1-phosphate synthase as found in Actinobacteria, produces an essential precursor for several different products, including mycothiol, which is a glutathione analog, and phosphatidylinositol, which is a phospholipid.	0

Protein sequences

>NZ_LT827010.1|WP_014695277.1|9193154_9194672_-|DUF2029-domain-containing-protein
MSAQPSTDRPDVPSATSDGFVRGLSQIIGGPLGSHATRPDARPHRFWTAPRFVLALTCLILALSWVQKSPCMSGDWQKNMQYTRFCYTDVLALYYAEGLSDGQVPYVGHEVEYPVVTGYFMGAIGLPVHWYGTTQNTKINQGSWFYNINALILSILAVATAAVLLALRRRRPWDAAIFALSPILLVTATVNWDFLAIGFAAVGLYLWVRRQPAWAGILLGLGAAAKLWPLFLLGPLLVLAMRSGRIRAFVEAALGTVAAWAVVNFPVWYWHHEAWLKFFRLNSERPVDWGTLWYVGRYLDGKWKSGAAGDQGPFQWLSDHVPTLNWVTYALFGLACLALVAVGLLAPKPPRLAQMAFLVVAFFLLTSKVWSQQYVLWLLPLVVLARPKWGAILAWTVAEIGYFAAFYAELIGAGGKPVIPEGTFVLASALRLITVAVLCGLVIREIWRPELDVVRQTYGGADPDAGELDGPDAPWIERMRLGFGLIKPTGPVELVPPDDPVVMKA
>NZ_LT827010.1|WP_014695275.1|9188682_9189456_+|deoxyribonuclease-IV
MRIGAHVDSADPLAEAAARGAEAVQFFLSDPQSYKNPAPRADVEQLRASEVDIYIHAPYRLNVASPNNRIRIPSRKLLMTHARAAAEIGAKGLIVHGGHVEGGDLTVGFDNWRKAFEYAEKDGGLPLPILIENTAGGDNACARRFDDLARLWDAVGSFGAGFCLDTCHAFAGGEDLTGIVDRVKAITGRIDLIHANDSKGGFDSGQDRHDNLGSGKIDPELVVAAIRASGATAIVETPGGVAGQSADIALLRERSGS
>NZ_LT827010.1|WP_014695274.1|9187586_9188552_-|hypothetical-protein
MSRQFRYRMAALVASGLIFGVPLLTNGTANADQLEPGARRVTFDGGMLGLSCGSKPSVERLRVPAESTLHVVNRTGHNARLELAGAPRGVIPENGAAEVVFRRGTTPVVLDPDCAGSDDPVPMLVTAVPSTPSALPDPAPGGSNAGTLPAIVAGSAGQSVAGSALPDDDATGSRPPHQVAGPRGVRDPDRRRTAKVHAAGETPRQDTDQKVKNDGSRTSVAGGPTFAGMPPGERKTVLPADRAAVVTASPAGTAPAAESPAAAEPPILTEPAAEPVAAIRPMRTTHPIGLLGLTAIVCVLGVLTAAIRAIVSQRASRSNLA
>NZ_LT827010.1|WP_014448192.1|9186999_9187290_-|30S-ribosomal-protein-S6
MRHYELMVILDPSLEERTVAPSLDQYLNVIRTAGGSVEKLDVWGRRRLSFEINKKAEGIYAVVDLQATPEAVAELDRQLRLNESILRTKVIRPETR
>NZ_LT827010.1|WP_014695273.1|9186361_9186934_-|single-stranded-DNA-binding-protein
MAGETVITVVGNLVNDPELRFTQSGAAVCSFRIASTPRTLDRQSGDWKDGEPLFLSCSVWRDAAEHVSESLQRGARVIVQGRLRQRSYDTKEGEKRTVIELEVDEIGPSLRYATAKVQKASRSGGGGGGFGASGGGGGGNRQFSGGNNSGGGGGRGNSNDYDDPWATAAPASSGGRSGGGNSSFDDEPPF
>NZ_LT827010.1|WP_007073789.1|9186053_9186293_-|30S-ribosomal-protein-S18
MAKAAALRKPKKKVNPLDKDGITYIDYKDTALLRKFISDRGKIRARRVTGVTSQQQRQIARAVKNAREMALLPYTATAR
>NZ_LT827010.1|WP_014695272.1|9185589_9186039_-|50S-ribosomal-protein-L9
MKIILTQEVSGLGTPGDIVEVKNGYGRNYLLPQGFAIQWTKGAEKQVAVIKRAREAREIRDLGQANEVKGQLAGLKVTLSARTGNGGRLFGSITPAEIVDAVKTAGGPSLDRRRLELPGHIKTTGSYNVQVKLHPEVTATFPVNVVAAK
>NZ_LT827010.1|WP_155123732.1|9180112_9184774_+|hypothetical-protein
MSRERRAADPWLTREREAEIDDAEPRWSALTDTGSMTPSPEALTWQRRADAWAQQSEIEPYSGGGGQAVEPANRWSDVAATGRPTFPADGTGWRTQTSEWRATGARWRQTTEWRSSTGSHVWRSTTEAWQPGDDDEQQQPTISGTAWPTPEDNTRDVSSSWSATKPVEQTWSSSGTPSWQQPATSWDSGRRTPGENTTDVAGWDRSGGSGWQSGPRDDGRHYVREDDRAAWRQADTEWSTRRGRRRAPEPDEQPSGGSGWSSGDETDNWAGHADTGNISYAPTSAPSFGSRSVRRGPQPPPPDDAAAAQRGQTPIQFGVRPGSRRAAPDEGPSGPIDTGAASAGQPERQRGQSRRGRGPQRYNANPTNWREDTASWDAEPDTSNWTRDPDTGQWSRAEDDPRVLAWRAEAARRDQMRQGDADEQPGRGEQPTPDGAVGWGGRRGQWDDEPSGPIGGVPGGPLPSSAVPDGPGSRPRSAMPAPRSAMPAPRSAMPSQRSAMPSQRSAMPSQRSATPSSGGAGWAAGGAPWNGADQPDPYSSGRIHADQPDAYTSGRIRADQGPGRFGAEQYDSGGRRRAPEADSGSWDARQGRPTGPEDDYAADGRRQGPMPPRALPAGRSGWPQQAGPRELPAGPSGSTTPEQSWPDRGQEQAGYGARQYGYETPRRTGAPETDGTFDLRRATGGNAGWSDPRSADPVGNSWSDPRSTGPADAAWTDARRGDVPGGRPDPRRADGPDAGGWGDARRAGQPDASRGDSGRDDGASWNGFGRGDGATWGDPGRGDGASWSDPGRGAGATGNGSGRGDGASWNDPGRAAFAGWGDSGRGEGPGWDGSRRAGGPDEASRGHSRRAGGSDTGDWRDRRRAGGADPGDWSDARRAGGPDDAAWPGSRRADGSDTGSWNDSRRGGAPDTGSWGDPRRADGPDTGGWHDAGRGGADTGSWGGTRRAGRPDDASGRGSRRGGAPDGDGWSDTRRVSGARAVPVEPSYGMRELPAAPERRDDDTSWRSNGYGEPTRDRAPSGEPRDPRKPAYGAQRELPSGPTPWPGTDDYQDEPGRYADPRRRDDRDDPPYGGTGGRGQNDRRPSAWNGSEPSSWDGSGGYRRDVSPGTPGYRTGPDTGGGGYRPAGPGGDWRADLNGGAGHDGGAAVTTGPAGGTSLTAAPVSGTAGYRAAATPPAASVPGPAGDWRAELNGAAPTSSVPGAGSAPVADWRAQMNGSTAAPTSSAAGYRASAAAGTDWRADMGAAPTVGATAPVSGATGYRPPGTPAPAADDWRREMARESAPADGDPQRFSTSDFPPFRPSGSAAVEGAANLALSATSVIAVPPASPAEAPLTADTPWPPRRQPGTAAAEEDTSWPPRRQAGTAAVEEDTSWPPRRQPGTAAVEEDTSWPPRRQAGTAAVEEDTSWPPRRQVSGALFENTGSYERRPVSSGVLSSRQNDLLNPDDEDEPETSSSPLAAVGYTVVWYGVPVVLFIAGMLLLNSGQRAHALQTLANAAPEFGISLTLSIIVAFGLRFATSSWKSASVGLAAAVVGGGLATVLSSAITGNSLS
>NZ_LT827010.1|WP_043513213.1|9178269_9179703_-|replicative-DNA-helicase
MSITDDARPDPRPPSQPSGGPQSGGSGRSDAPTGGSFDKAPPQDVAAEQGVLGGMLLSKDAIADVVEILKTGDFYRPIHATVFDVILDLYGRGEPADALTVAAALADSGDLQRVGGVPYLHTLIESVPTAANASYYARIVADRAILRRLVEAGTKIVQLGYGAGGNGGRDVDDIVDRAQQAIYDVTEKRVSEDFAALGDMLQPTLDEIEAVGASGGVMQGVPTGFQDLDRLLNGLHPGQLIIVAGRPGLGKSTASMDFARNAAIRHGCASAIFSLEMSKIEMVMRLLSAEARVPLHTLRSGQLSDDDWTKLARCMGEISEAPIFVDDTPNMNLMEIRAKARRLKQRHNLKLLVIDYLQLMSSPKKTESRQQEVSELSRGLKLLAKEVECPVIGVSQLNRGPEQRTDKRPQLSDLRESGSIEQDADVVILLHRDDYYDKESPRAGEADFIVAKHRNGPTDTITVAAQLHLSRFVDMAI
>NZ_LT827010.1|WP_099344256.1|9177666_9177972_+|YbaB/EbfC-family-nucleoid-associated-protein
MRNDLANVYGRYEELRSGVDELQRSLATMQVSATSPDGLVRATVNADGDLVDLRLDQQACREWNVETLARVIVETVQHASAGKHRQVEQLVTTHRPPDETA
>NZ_LT827010.1|WP_014695279.1|9197686_9198121_-|DUF5318-domain-containing-protein
MRTQRQVVDYSLQRRAVLRDVRNGRISPLEVCDASPYLKNAATFHGEPTDERCPICRRENLTLVHYVYGDELKQSAGQAHKAAELPVLAMTLRECQVFVVEVCRSCSWNHLIERYVLGRDALDADEPPMQWKTGSVSHVGEGRR
>NZ_LT827010.1|WP_014695280.1|9198282_9198936_+|PadR-family-transcriptional-regulator
MLELAILGLLQEAPMHGYELRKELATKLGTLRAAISYGTLYPTLKRLKLAGWISEAVANNNEIVPPMTSKRGRVVYKITADGKERFSELLATAGPETYDDAGFGVHFAFFSRTDRATRLRILEGRRRRVEERREGLREILARAADRLDAYTLELQRHGLDACEREVRWLEELITNERSGRTPAFRQRAGLAGAYPDSAAHPAAESPSEPPRPHLDRP
>NZ_LT827010.1|WP_043513219.1|9198959_9200039_+|inositol-3-phosphate-synthase
MGSVRVAIVGVGNCASSLVQGVEYYKNADPNDRVPGLMHVTFGDYHVSDVKFVAAFDVDAKKVGMDLSEAIVASENNTIKLTDVPPTGVTVQRGPTFDGLGTYYREIIEESEAEPVDVVQVLRDAEVDVLVSYLPVGSEQADKFYAQAAIDAGVAFVNALPVFIASDPEWAQKFADAGVPIVGDDIKSQVGATIVHRALAKLFEDRGVELLRTYQLNFGGNMDFMNMLERNRLVSKKISKTQSVTSQIPHEMIKSDVHIGPSDHVPWLDDRKWAYIRLEGRSFGDTPLNAELKLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPILSASSYFMKSPPVQYSDHDAHNAVEAFIKGETER
>NZ_LT827010.1|WP_043513222.1|9200184_9201327_+|CapA-family-protein
MAVSAGALYAFGPWSADTPDLASAARPLDPPVSVPGRTVSVLAAGDILAHPELWDQARRDGNGTMDFAPMMASAKETVSGADLALCHMETAVAPPGGPYIGFPKFSVPREVVQGIKSLGYDGCSTASNHSIDQGFEGVQRTLDALDAAGLGHTGSYRTAADAAKPKIYTAKGVKIAHLSYTKDFNGLKPPAGKAWVANQINVTKIRKDAAAARKAGAQIVIVSMHWGTEYEHEPDVDQQTWARAIAQIKDVDIVFGHHAHVVQPVEKIGNTWIIYGMGNQIARHAEPINSNRDGAMMKVTFGPSSVPGRWKVMALEAIPTFVDLNPNIRLVDLPRELAKPDLSAPQRKIYEAAVDRIDGNLLTHGASAAGLIVHGTGKSS
>NZ_LT827010.1|WP_014695283.1|9201406_9203608_+|HAMP-domain-containing-protein
MSSRSAQTVTSRAAELAQEQEELLAWRRRALTQQLPAAAFPAGTSAPSLAYLWASFFVVVAAVLGLTVNAHTGALPAIADSQRDIAIKLANGFEAEIHQETTVLDRILQSRGSLSQADLLVRAIADGNRVTGAAIVDMTTRKSVVAKGDAVPLDALPNPLPSGHPVAVTTADGPMLVYSAALDGTQSLLAVQPIFMRTLRLNPDAKHGIHLLTGDGKSSLLQGAHAIDVAHQAKVFDGLYGITSSKVREVIVDEWPDTRLIAAAAPVGRTGLVVVSLLTAPVAKGTTVTKGLLIGASLLAVALLSFLIMRKSLVRPVRELLNQAKEDASGATTRERRPLGVREAHRIAKALATTVGAEFPEGRRWRPSVTQGLALAAVIALLWPAAAVAMVWRSPDPQLPAQLVRDGETRAESAGFTLGHFLDDGLATVSRTSRLVKTDDLAATGHTLQRALADDDRLRALYLVDEKGEVLSKTGRQPLRTPVPVPGEVGIHLDDAIGRLPVVYAYNELPSGYAVIGEFDPDRLLGQIGRVKGRVRVVDSELRTLLDSRGYVAYQPLTGRLAREVAVEALPGVTVGRGAAADGHPELAAAVGMVEPASVAHLEWAVVVEQDVSGVRLPEMVEHRWLLLVAAVVVGIVLVTHMWQFYIFVVPLRRLAFFADKMSSGDLDHPVPPQRHDDIGAVAICLEICRQVRHTGSARFGGALRLRGEGPDRTTVLSLADRAVRSHSRSSKG
>NZ_LT827010.1|WP_014695284.1|9203610_9204885_+|poly-gamma-glutamate-synthase-PgsB
MLYLYAVFSVCCLALLAAGVIEQRNHYRNLKLMPSRVLVNGIRGKSSITRLCAGALRGGNKVVVAKTTGTAARFIFPDASEEPVHRKFGIANVVEQIGIVRRAAVYHPDALVIECMAVMPALQEINQSKLIQSNIGVLCNVREDHLAEMGPTLDDVARSLSRSMPEGGVCITAEKDRLAILQEEADKRKCRLIAVDPESVTDREMAGFGWITFKENVAIALAVAAQLGVDRQSALAGMWAAPPDPGVLSVARVLYRDKRVRFANIFAANDPESTFMNIAQLEKQGLISRPLTMVINCRPDRVERNGQMGALAERVQPQHIVLIGEMTRSAKVAVPAGLQDRVTDLGKMPGDRMLAELMAVVGPDASIVAVGNIHGQGEVLLHELAALPSWEPQGSGRSDSMLRVSTTPGFDVLAETVFLERTHR
>NZ_LT827010.1|WP_014695285.1|9204881_9205367_+|poly-gamma-glutamate-biosynthesis-protein-PgsC/CapC
MTFGGELSAQLSTACLGIGLVFALLCYLTTNLSPGGMITPGWIALALIEDKMHAAVIVGMTVVTYTLTKVLQRMVILYGKRLFAAIVLLSVFLQLTLFVLVQQDLPLLFAHQTLGFVAPGLITYQLVRQPPKATLLATGLVTAMTYGVAFSGIVAGLVPTT
>NZ_LT827010.1|WP_014695286.1|9205377_9206421_+|C40-family-peptidase
MNYQTYTRSQATLVTLAILLVLVGGGSVAYAAARSTMPEAVEISLGSEDQGSVAAGLGYRVRRGVDPARTEFLDATGKVMATMTDTSRTVHLNGPERTFAEARFTKAKLVTEYWVRLAPKPWHKGAETEKWFVDWFTKARTDRSPDVLALAFEYTYTAKPKKDATGRQYSGDAAFGPLSDIDPDGRAENSDFYDYLGVPWTFPDKKEKPSASHIRSLDCSGFLRMVYGYRLGYPLRGTNNPGPGLPRQAAGLAAVGPGTLLMPNTGKRAVNLDRLLPGDMVFFNAGPIKGTHIEHSGMFLGVDDRGHYRFISSRTKANGPTMGDAGGESILDGTGHWAELWRTARRI
>NZ_LT827010.1|WP_099344257.1|9206437_9207196_-|hypothetical-protein
MSPSNPYRDPKADERTTIRQAARAIADQDANGNRDRLFSDLGFVVHRGTDPATGRAFDMYIATGTDKRTWGAVLIDTTRKPGIVLEVPHTGFDLNTEKLGLALHREVDSSVLLVAGAHRQAAGGLGDVAHNDKSLFHLFATELAGKGLEQLQLHGYADKNLPDSEAVVSTGKARVGPLAREVADALADAGVDICRAWKRRCGELEGKTNAQGRVASLEGDQFVHVEMSYSIRRDPGSWDRLVPDLAARINEG
>NZ_LT827010.1|WP_014695288.1|9207409_9207865_-|methylated-DNA--[protein]-cysteine-S-methyltransferase
MFVVESPIGPLGVAVEGDVVVGVRFGAAPGPAAEHPAAAQLTAYFAGESTAFTVPVRMRGGSDFERAVWTEIAKIPYGEMMTYGAIATALGDPGAARAVGTACNHNPVPVIVPCHRVVGAGGRMVGFGGGLERKRRLLELEARVALTRAWS

Crispr_ID: NZ_LT827010_25

• CRISPR_ID: NZ_LT827010_25
• CRISPR_location: 9229981-9230065
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT827010_25

Consensus_repeat	Method
CGATCCCGCGTCCGACCCGACCC	CRISPRCasFinder

spacers of NZ_LT827010_25

>25.1|9230004|39|NZ_LT827010|CRISPRCasFinder
GGCCCACTTCAGCGCCGCCCAGGTCCGGCCCAATCCCGC

CRISPR arrays and Neighbor proteins around NZ_LT827010_25

CRISPR arrays

The CRISPR arrays of NZ_LT827010_25

>merge|NZ_LT827010|25|9229981-9230065|CRISPRCasFinder
CGATCCCGCGTCCGACCCGACCCGGCCCACTTCAGCGCCGCCCAGGTCCGGCCCAATCCCGCGACGCCGGGGTCCGGCCCGACCC

>NZ_LT827010|25|21|9229981-9230065|CRISPRCasFinder
CGATCCCGCGTCCGACCCGACCC	GGCCCACTTCAGCGCCGCCCAGGTCCGGCCCAATCCCGC
GACGCCGGGGTCCGGCCCGACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT827010.1|WP_014695313.1|9238826_9238964_-|50S-ribosomal-protein-L34	unknown	unknown	gnl|CDD|179004
NZ_LT827010.1|WP_080128173.1|9238179_9238437_-|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|376620
NZ_LT827010.1|WP_014695298.1|9220891_9222109_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_172898949.1|9220178_9220895_+|RNA-polymerase-sigma-factor-SigM	unknown	unknown	gnl|CDD|236604
NZ_LT827010.1|WP_014695301.1|9223629_9224781_+|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl|CDD|119407
NZ_LT827010.1|WP_014695303.1|9225626_9226937_+|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl|CDD|224089
NZ_LT827010.1|WP_014695307.1|9233039_9234101_-|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105
NZ_LT827010.1|WP_014695309.1|9235534_9236422_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl|CDD|234637
NZ_LT827010.1|WP_014695296.1|9218456_9220010_+|protein-kinase	unknown	unknown	gnl|CDD|270875
NZ_LT827010.1|WP_014695302.1|9224781_9225432_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT827010.1|WP_014695306.1|9232120_9232753_-|hypothetical-protein	unknown	unknown	gnl|CDD|130070
NZ_LT827010.1|WP_014695300.1|9223189_9223507_+|thioredoxin	unknown	unknown	gnl|CDD|200072
NZ_LT827010.1|WP_014695311.1|9237155_9238178_-|membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|234941
NZ_LT827010.1|WP_014695299.1|9222213_9223173_+|thioredoxin-disulfide-reductase	unknown	unknown	gnl|CDD|273540
NZ_LT827010.1|WP_014695304.1|9226933_9227896_+|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234948
NZ_LT827010.1|WP_099344258.1|9216558_9218235_+|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl|CDD|240528
NZ_LT827010.1|WP_014695312.1|9238433_9238790_-|ribonuclease-P-protein-component	unknown	unknown	gnl|CDD|235126
NZ_LT827010.1|WP_172898950.1|9234097_9234898_-|ParA-family-protein	unknown	unknown	gnl|CDD|224113
NZ_LT827010.1|WP_014695310.1|9236423_9237011_-|single-stranded-DNA-binding-protein	unknown	unknown	gnl|CDD|224760

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT827010.1|WP_014695313.1|9238826_9238964_-|50S-ribosomal-protein-L34	gnl|CDD|179004	PRK00399, rpmH, 50S ribosomal protein L34; Reviewed.	4.08947e-09
NZ_LT827010.1|WP_080128173.1|9238179_9238437_-|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	1.28634e-36
NZ_LT827010.1|WP_172898949.1|9220178_9220895_+|RNA-polymerase-sigma-factor-SigM	gnl|CDD|236604	PRK09643, PRK09643, RNA polymerase sigma factor SigM; Reviewed.	3.41905e-79
NZ_LT827010.1|WP_014695301.1|9223629_9224781_+|N-acetylmuramoyl-L-alanine-amidase	gnl|CDD|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	1.206e-51
NZ_LT827010.1|WP_014695303.1|9225626_9226937_+|PLP-dependent-aminotransferase-family-protein	gnl|CDD|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	6.12762e-117
NZ_LT827010.1|WP_014695307.1|9233039_9234101_-|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	5.41711e-73
NZ_LT827010.1|WP_014695309.1|9235534_9236422_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl|CDD|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	2.34229e-69
NZ_LT827010.1|WP_014695296.1|9218456_9220010_+|protein-kinase	gnl|CDD|270875	cd13973, PK_MviN-like, Pseudokinase domain of the peptidoglycan biosynthetic protein MviN. The pseudokinase domain shows similarity to protein kinases but lacks crucial residues for catalytic activity. This family is composed of the mycobacterial protein MviN and similar proteins. MviN is an integral membrane protein that is essential for growth and is required for cell wall integrity and peptidogylcan (PG) biosynthesis. It comprises of 14 predicted transmembrane (TM) helices at the N-terminus, followed by an intracellular pseudokinase domain linked through a single TM helix to a carbohydrate binding extracellular domain. Phosphorylation of the MviN pseudokinase domain by the PG-sensitive serine/threonine protein kinase PknB recruits a forkhead associated (FHA) domain protein FhaA, which modulates local PG synthesis at cell poles and the septum. The MviN pseudokinase forms a canonical receptor kinase dimer.	4.36548e-60
NZ_LT827010.1|WP_014695306.1|9232120_9232753_-|hypothetical-protein	gnl|CDD|130070	TIGR00997, Probable_intracellular_septation_protein_A, intracellular septation protein A. This partially characterized protein, whose absence can cause a cell division defect in an intracellularly replicating bacterium, is found only so far only in the Proteobacteria. [Cellular processes, Cell division].	0.000660972
NZ_LT827010.1|WP_014695300.1|9223189_9223507_+|thioredoxin	gnl|CDD|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	4.21647e-40
NZ_LT827010.1|WP_014695311.1|9237155_9238178_-|membrane-protein-insertase-YidC	gnl|CDD|234941	PRK01315, PRK01315, putative inner membrane protein translocase component YidC; Provisional.	9.77621e-80
NZ_LT827010.1|WP_014695299.1|9222213_9223173_+|thioredoxin-disulfide-reductase	gnl|CDD|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.96168e-157
NZ_LT827010.1|WP_014695304.1|9226933_9227896_+|D-alanine--D-alanine-ligase	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.1415e-93
NZ_LT827010.1|WP_099344258.1|9216558_9218235_+|murein-biosynthesis-integral-membrane-protein-MurJ	gnl|CDD|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	4.6859e-113
NZ_LT827010.1|WP_014695312.1|9238433_9238790_-|ribonuclease-P-protein-component	gnl|CDD|235126	PRK03459, rnpA, ribonuclease P; Reviewed.	8.65899e-25
NZ_LT827010.1|WP_172898950.1|9234097_9234898_-|ParA-family-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	6.85776e-86
NZ_LT827010.1|WP_014695310.1|9236423_9237011_-|single-stranded-DNA-binding-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	1.20779e-40

Protein sequences

>NZ_LT827010.1|WP_014695304.1|9226933_9227896_+|D-alanine--D-alanine-ligase
MITTMELRVLVLAGGLSYERDVSLRSGRRVLDALRSRGIEAELHDADVSLLPALQADPPDAVVIALHGATGEDGSLRGVLDLCAVPYVGADARTARLAWDKPSAKARLRESGIPTPDWVALPHDRFSELGAVAVLDRIVSRLGLPLMVKPAQGGSGLGAAVVRDAADLPAAMVGCFAYDSTALVEQYVSGTRLAVSIVDLGSGPRALPIVEIVPRDGVYDYAARYTAGLTTWHVPARLSAAVASRVSETALAAYQALGLRDLSRIDVIVGEDGEAQVLGCNVSPGMTETSLLPLAVQADGADLGEILGVLVERAVDRKAL
>NZ_LT827010.1|WP_014695303.1|9225626_9226937_+|PLP-dependent-aminotransferase-family-protein
MTGTTQDDYTDRYARRVRGMTTSEIRALFAVASRPEVVSLAGGSPFIAALPLDAVGEMMSRLAVDHGATSLQYGIGQGTIELRERICEVMALSGIQGASPDDVVVTVGGQQALDLLARLFLDPGDVVLAEGPTYVGALGVFQAAQAQVRHVAMDADGLIPEALEEAIAAGVAAGRPAKFLYTIPTFQNPAGVTLSEQRRERVLDICERAGLLVIEDDPYGMLAFEGDAPRPLRARRRDGVFYCSTFSKTFAPGLRVGWILAPHAVREKLVMMSEANVLCPSAFAQGAVTQYLTTMPWREQIKVYREIYRERRDALLSALTDLMPAGTAWTRPAGGLFVWATLPDGLDSKAMMPRAIAARVAYVPGTGFYADGTGRGNMRLNFSFSAPERLREGVRRLSGVMEQDLAMRAVFGGSAALSSQRRRGPAAADAPGPDLA
>NZ_LT827010.1|WP_014695302.1|9224781_9225432_-|hypothetical-protein
MSRRLVNLTLDTLEDLPRPCRQCVYWELDPVSAERACASGDPGLEKEAWVSQTLLEWGSCGKLAYVDGMPAGFVMFAPPAYVPRSMAFPTSPVSADAALLTTAKVVPAFAGGGLGRMLVQGVARDLTKRGVKAIEAFGDAKPDEDAEGACVAPVDFFLSVGFKTVRPHPRYPRLRLELRTALSWKSDVEYALEKLLGSMSPEKLLRPMPATSSIEN
>NZ_LT827010.1|WP_014695301.1|9223629_9224781_+|N-acetylmuramoyl-L-alanine-amidase
MRSIRRGDTGPAVSEIRSILIGLELLAEPEPDVFDEPLENAVREFQQSRGLGVDGMVGDETWRALDGARWRLGSRTLFHSVPGALTGEDVHALQERLLEMGYDPGRPDSIYGARTARAVAQFQREVGLAPDGSVGPQTMKALRRLGRKVVGGRPQWLREAEAFRQSGPNLVGKTIVIDPGHGGGADTGVLVPDGPLRWTEADLVFDLAARLEGRLAAAGMRVHLTRGPQPAEPMSGTDRAALANSLGADLLISLHLDGHPSEAAEGVATYHYGTGSGLSSTVGERLAALVQREIVVRTGMHDCRTHAKTWDLLRLTRMPAVRVDLGYLTSPADRERLVNPMFREQIVEAILAAVQRMYFPVERDVPTGSIDVRALRMALADRT
>NZ_LT827010.1|WP_014695300.1|9223189_9223507_+|thioredoxin
MKVVTDKSFATDVLASDKPVLVDFWAEWCVPCKKVDPLLAEIAESELGSQVEIVKVNIDENPQTALAYQVMSVPTLAIFKDGERVNLVTGAKPKSFLVNFIESAL
>NZ_LT827010.1|WP_014695299.1|9222213_9223173_+|thioredoxin-disulfide-reductase
MDEVRNLIIIGSGPSGYTAALYAARAELKPLVIEGVQSGGALMTTTEVENFPGHRDGIMGPELMDNMRAQAEKFGAEFITDDVSRVELSDKPTEAGTEGLKTVWVGDQQYFARAVILATGSAWRPIGVPGEQELLGHGVSACATCDGFFFRNQHIVVVGGGDSAMEEATFLTRFAETVTIVHRRDSFRASKVMQKRALDNEKIKVEWNSVVEEILGADGKVVGVRLRNVQTNETKVLDVTGVFVAIGHDPRSELFKGQVELDDEGYVKVQSPSTRTNIPGVFAAGDLVDHTYRQAITASGTGCAAALDAERFIASFVEL
>NZ_LT827010.1|WP_014695298.1|9220891_9222109_+|hypothetical-protein
MTGADFHGVDIDLLADFVGGALDGTPDADRVAALLAADPAWQEAYELLAPEMATVGALLTGLPAEPMPVDVVARLDAALAEATVGTGFNLTDTTGSANATPVDHATTADSTPADFTTTESATVEGTVADRSTTTDSAIADRITADRRTSVDSTTTDRAGEADATTASSPTPVSGAPRVEGSGEAGGATDVHKSVVDLDERRRRGAKRWLRIAAPIGVAAGAVAFFGYTAGQQHSESDSAASKAAAGAADAMSPEGAPAVLTSGLDYSLATLGQLPKRAIEPVEPHSDSGLASGLPGGGAIGASAGPSDRASTDAAANGPAAGDRWLGELARLRAPQALQDCLDAIARENGGGWLTAESLDYARFNGKSALVVRFSAANGQWAWASGVNCGLPGGGADTLGSVPVR
>NZ_LT827010.1|WP_172898949.1|9220178_9220895_+|RNA-polymerase-sigma-factor-SigM
MAGVTLRDVPPGGLGAGDPVPSDAELVRAHVAGDREAFAELVRRHRDRLWAVALRTTGDREEAADAVQDALLSAHRAAAGFRGDSAVTTWLHRIVVNACLDRIRRRQAHPTVPLPDHHSGDDRRSAPEPVAPTPDQDTVLLVREALAALPVEQRAAIVLVDVQGYGVAEAAAMLGIAEGTVKSRCARGRARMALALRDLREAHSEPGHDGNRTGAAGVPSRSGGATPQPAGREGRDQR
>NZ_LT827010.1|WP_014695296.1|9218456_9220010_+|protein-kinase
MTQVGEGHETAADEAGPVLTFGEPAVGEILAERYQLEQHVNNDSAGRQVWRGIDVVLRRPVAVVLRHPGGDSATEMLQAAVAASRVIHPNLVGVYDAIDEQQRAYVVREWVDGESLRDLIASEGPLDPARAIAIAHSVSDALAAVHATGMIHGNVHPGTTLIGDDGRVVLADARADAADSSEADVRAVGGLLYFALTGRWPHAEVGRSALPDATRDGSGAPAAPRQARAGVPAYLDDLTMDLLDGRIAAPPAEALTAELGRLDAAAEDEDFEDVGPLRFVQGGGTPTEPARSTRKILVGVGALVIIAIVGLVFGIRAINKSSHPEASPSSPVQAGAGAQPSSAGTASGAPLGQPKKIPLTADMVRIVDPPQGERKDSGESDAVVDGNPDTAWKLSYYLQPNFGGRKPGMGVLIHLKEPRALSEVRVSLSAPGAVLDLRVGDKDPGDNSAGDDTIVKTYKKLSDADSTDVSTGDQPILNGFDPDKKYQYVLVFLTKLPRNEDTPGYQVNVNEIELYGY
>NZ_LT827010.1|WP_099344258.1|9216558_9218235_+|murein-biosynthesis-integral-membrane-protein-MurJ
MPADGSVAEPEVPEAPEAGGGGLLRSSAIMAIGTLASRVTGFLRTTLLVAALGSAALGDAFNTANTMPNIVYDILLGGVLTAAHVPLLIRARNRSAEYGEEFEQRLFTILLGLLALITAGAMIAAPWLIDLYASRFPPAQHRVASMFLLFFLPQIFFYGFSAVAGASLNSRGRFAAAMWTPVLNNVVVIGVLGAFMAVTHGKLTPDNITDGQVTYLGIGVTAGVAVQALGLIPAMHRMGFNWRLRFDFRRAELTQIWGMASWTLVYVLAQQVALLVYTNLANAAGAQGVKEGIRYGVGLTPWTNAYMFFQLPYAVVAISIITAILPKMTQSAAEGRFDRLVTELREGLGLSLTLMLPAVAVLFGAAGEICLVVFAHGKSSPADAAMVAGVLRVFAVALTPFAVLQLLQRGFYALGDTRTPAMIALGSTGVGGLTAFLLSRVLPTADVVLGIAGAQGVAWACGCVISVVVLRRRLGRLGGGALFRVISKAGLASLATLLVVFLIHHTVTPHLHDSFPLTAVVLAVEGVLGLGAFVIAATLLRVPEVGQVIGMVRRKLGR
>NZ_LT827010.1|WP_014695306.1|9232120_9232753_-|hypothetical-protein
MRLDAGMTAMIRSMAADLGLPLVGYYGLHALGADDTTALLAGTVAAAVRIGWVAIRSRSLSPFSILMGSVFGIGLVFTLVTGDPRFMLIKHSIMSAVIGMVFLATALWGRKPLTLSAQQSFMPAKAAELAEQFKTSAAVRRGHRTASTVWGAGLLVEAAVRAVLVFLLPVDVMVGLSTALTVVTFTVLLGWNARYIAAHRRAAAAVLVAA
>NZ_LT827010.1|WP_014695307.1|9233039_9234101_-|ParB/RepB/Spo0J-family-partition-protein
MKNRPRGGLGRGLGALIPTAPAAEPESPVAVAADGLPSSAPSVAPVSIPAPSPASAPPAVAVLADDELAPVPGARFAELPVSSIEPNAKQPRHVFDEEALEELKISIQEVGFLQPIVVRELGDGRYELVMGERRWRAAQAVGRESIPAIIRDTPDDVMLRDALLENIHRANLNPLEEAAAYSQLLEEFGVSHEELARRIGRSRPQISNTIRLMNLPAPVQRRVAAGVLSAGHARALLGLEGSEAQEELAKRIVAEGLSVRATEEIVKLAESEGPARKAAPARRAKVHAPALNDLAERLSDRFDTRVKVDIGRNKGKITIEFATVDDLERIVGMIGVEEEGARSSTPSGVDSDE
>NZ_LT827010.1|WP_172898950.1|9234097_9234898_-|ParA-family-protein
MPRPDHPRVICVANQKGGVGKTTTTVNLAVALALHGNRVLVVDLDPQGNASTGLNVPHHAGVPDVYDCLIDNVPLAEVAQAVEGIPNLFCVPATIDLAGAEIELVSVVARESRLARAIASHPEKFDYVFIDCPPSLGLLTVNALCAAQEVLIPIQCEYYALEGLNQLINNINLVRQHLNPTLDVSTILLTMYDRRTRLADAVEQDVRNHFGTKVLNAVIPRNVRVSEAPSYGQSVMTYDPGSRGATSYFEAALEIAVRGVNTGGAA
>NZ_LT827010.1|WP_014695309.1|9235534_9236422_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MTDPRFGAGEGGPGVTAPGPPSSRGPSGSYAARPGLPGAAGVPVPAEEPADVDVLQPPAVMEMAAREVFGDRLALAGRFAQLLATEGVLRGLIGPRETPRLWERHLVNCGVMSQLFPIGASVVDVGSGAGLPGIVLAVARPDLEITLVEPLARRTAFLTETVDELELHNVTVVRGRASEVIGQVADADVVTARAVAALDVLAGWCLPLARVGGTLLALKGASAEEEIGEHGAQIARLGGGRPEIRFCGAGLIEPPATVVEIVKEREVAAGRGRDRVVRAARREGRGGGRGNKRRG
>NZ_LT827010.1|WP_014695310.1|9236423_9237011_-|single-stranded-DNA-binding-protein
MTDTSTPPASESPAPSAVAPETDAAPSEAVSAEGKKSESVASDSDLFRQSEIAADYVEGLLDILDYDGDIDELVSAGRPMVEVVGGRLQPLVGQRGATLEALQELTRLAIFRATGSPSRLLLDIGGYRASRRKELAAVARNAVEKVKEHGEAVRLEPMSAFERKCVHDVVNAIAGVQSESEGVEPNRRIVVRAAE
>NZ_LT827010.1|WP_014695311.1|9237155_9238178_-|membrane-protein-insertase-YidC
MSLDWIYYAISWILLRWHSLWDAIGIPDDRVLGTNWSWVLSIFFLVVTLRVILFPVFVKQIKSQRAMQALQPKVKALQEKHKGDRETLQKEMMELYKTEKANPLMGCLPMFLQVPVFIGLFHVLRHLNPNLPEHLKTIYGWKLEQFNSATAAHLFNVPISAKFGSTPAELAAMHANGTTVKVLAGVLILVMMGTTFLTSRQMILKTGWAEDPQQKMVQRLMLYGIPCSLLISGSLFPIGVVIYWVTNNLFTLGQQQWVLRKFPPPNMAGKGGATTARPANATASDVKNPVQPGRSGGLFGRKAVAEEATPVVDTKALAPKPGAKPVNPKKGARPANKPKG
>NZ_LT827010.1|WP_080128173.1|9238179_9238437_-|membrane-protein-insertion-efficiency-factor-YidD
MSLAARLLTAAVVAYRRYLSPALPARCRFYPSCSAYAQEALARHGAVRGTGLAIWRLLRCHPFHPGGYDPVPDPIRHRPADVTGA
>NZ_LT827010.1|WP_014695312.1|9238433_9238790_-|ribonuclease-P-protein-component
MLAATQRLRRSADFAAAIRGGRRAGRGTLVVHLLIEEPAHASEARAGFVVSKAVGNAVVRNKVRRRLRHLVRPLLADLPPGALLVVRALPPAAQAGYAELGIDLDGALASARRPRRPR
>NZ_LT827010.1|WP_014695313.1|9238826_9238964_-|50S-ribosomal-protein-L34
MSKRTYQPNNRRRAKTHGFRLRMRTRAGRAILSARRGKGRDKLSA

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT827010_20	20.2|7934399|36|NZ_LT827010|PILER-CR	7934399-7934434	36	NZ_LT827010.1	7934450-7934485	0	1.0
NZ_LT827010_24	24.1|9194908|24|NZ_LT827010|CRISPRCasFinder	9194908-9194931	24	NZ_LT827010.1	9194941-9194964	0	1.0
NZ_LT827010_22	22.2|8787154|17|NZ_LT827010|CRISPRCasFinder	8787154-8787170	17	NZ_LT827010.1	2972222-2972238	1	0.941
NZ_LT827010_12	12.4|5588655|19|NZ_LT827010|CRISPRCasFinder	5588655-5588673	19	NZ_LT827010.1	5835797-5835815	2	0.895

1. spacer 20.2|7934399|36|NZ_LT827010|PILER-CR matches to position: 7934450-7934485, mismatch: 0, identity: 1.0

cgggttgcggctacgagggtgagcggcggcgggtga	CRISPR spacer
cgggttgcggctacgagggtgagcggcggcgggtga	Protospacer
************************************

2. spacer 24.1|9194908|24|NZ_LT827010|CRISPRCasFinder matches to position: 9194941-9194964, mismatch: 0, identity: 1.0

accaccgttgttgttgccaccgcc	CRISPR spacer
accaccgttgttgttgccaccgcc	Protospacer
************************

3. spacer 22.2|8787154|17|NZ_LT827010|CRISPRCasFinder matches to position: 2972222-2972238, mismatch: 1, identity: 0.941

gacgagcaccacgggcg	CRISPR spacer
gacgagcaccccgggcg	Protospacer
********** ******

4. spacer 12.4|5588655|19|NZ_LT827010|CRISPRCasFinder matches to position: 5835797-5835815, mismatch: 2, identity: 0.895

gcgggacgatgcactgccg	CRISPR spacer
gcgggacgaggcgctgccg	Protospacer
********* **.******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP044544	Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence	90710-90735	3	0.885
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP027024	Streptomyces sp. WAC00288 plasmid p2, complete sequence	91895-91920	3	0.885
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP020556	Streptomyces sp. Sge12 plasmid pSGE, complete sequence	117396-117421	3	0.885
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	253539-253564	3	0.885
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	822805-822830	3	0.885
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	670377-670402	3	0.885
NZ_LT827010_1	1.1|316948|26|NZ_LT827010|CRISPRCasFinder	316948-316973	26	NZ_CP040819	Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence	162422-162447	4	0.846
NZ_LT827010_1	1.1|316948|26|NZ_LT827010|CRISPRCasFinder	316948-316973	26	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	790820-790845	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	193036-193061	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	30677-30702	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	1731331-1731356	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_015951	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence	72415-72440	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_015951	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence	75562-75587	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP035419	Leisingera sp. NJS204 plasmid unnamed2, complete sequence	88391-88416	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP038239	Leisingera sp. NJS201 plasmid unnamed5, complete sequence	2863-2888	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3567326-3567351	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP046575	Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence	110524-110549	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	CP007643	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence	138559-138584	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	136921-136946	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	136921-136946	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP024873	Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence	41829-41854	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	40540-40565	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	104131-104156	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MK937601	Gordonia phage Charming, complete genome	28718-28743	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976519	Gordonia phage Tangent, complete genome	28721-28746	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976510	Gordonia phage Fosterous, complete genome	29134-29159	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976518	Gordonia phage Stultus, complete genome	28284-28309	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH479924	Gordonia phage Rofo, complete genome	29199-29224	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MK937594	Gordonia phage Galadriel, complete genome	29623-29648	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MN329673	Gordonia phage Jabberwocky, complete genome	29762-29787	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MT723934	Gordonia phage Love, complete genome	30133-30158	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH651166	Gordonia phage Angelicage, complete genome	29461-29486	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MT639640	Gordonia phage Paries, complete genome	29801-29826	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MK977702	Gordonia terrae phage McKinley, complete genome	30171-30196	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_042108	Gordonia phage Brandonk123, complete genome	29209-29234	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976514	Gordonia phage Nordenberg, complete genome	28335-28360	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976508	Gordonia phage Bibwit, complete genome	28862-28887	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976506	Gordonia phage Affeca, complete genome	29044-29069	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MN329677	Gordonia phage Keitabear, complete genome	30570-30595	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MH976507	Gordonia phage Ailee, complete genome	29543-29568	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MT498035	Gordonia Phage Barsten, complete genome	28675-28700	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_031239	Gordonia phage Vivi2, complete genome	29888-29913	4	0.846
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	946152-946177	4	0.846
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP025508	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence	408582-408607	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP030764	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence	341312-341337	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022667	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence	228996-229021	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP050087	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence	407367-407392	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	192943-192968	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_DQ996271	Burkholderia glumae BGR1 plasmid pBGF3, complete sequence	22906-22931	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1241468-1241493	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_LR134455	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence	136116-136141	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	12202-12227	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	437786-437811	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	675257-675282	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	833032-833057	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	330677-330702	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	192952-192977	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	677673-677698	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP021127	Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence	91317-91342	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP020372	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence	23830-23855	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	692567-692592	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	677679-677704	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	692567-692592	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	682808-682833	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	692568-692593	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	682808-682833	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1793265-1793290	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	12347-12372	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	682808-682833	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	682808-682833	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	682808-682833	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1423033-1423058	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	679866-679891	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	682795-682820	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	692564-692589	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	682810-682835	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1390221-1390246	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	692570-692595	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1390221-1390246	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP011869	Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence	242079-242104	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	42925-42950	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	MN850588	Escherichia phage sortregn, complete genome	29157-29182	5	0.808
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	124293-124318	5	0.808
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP012916	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence	49911-49936	5	0.808
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	39876-39901	5	0.808
NZ_LT827010_6	6.1|2214158|26|NZ_LT827010|CRISPRCasFinder	2214158-2214183	26	NZ_CP032341	Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence	190135-190160	5	0.808
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	656074-656099	6	0.769
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	220990-221015	6	0.769
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP006570	Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence	398396-398421	6	0.769
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1458777-1458802	6	0.769
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	608736-608761	6	0.769
NZ_LT827010_5	5.1|1847624|26|NZ_LT827010|CRISPRCasFinder	1847624-1847649	26	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	673598-673623	6	0.769
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	MK937598	Microbacterium phage Celaena, complete genome	13181-13212	6	0.812
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1511933-1511964	7	0.781
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	301327-301358	7	0.781
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NZ_CP020813	Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence	47314-47345	7	0.781
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_004808	Streptomyces rochei plasmid pSLA2-L DNA, complete sequence	60857-60888	7	0.781
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	490013-490044	8	0.75
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1323056-1323087	8	0.75
NZ_LT827010_23	23.2|8984781|27|NZ_LT827010|PILER-CR	8984781-8984807	27	NZ_CP016620	Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence	24366-24392	8	0.704
NZ_LT827010_15	15.1|6284702|37|NZ_LT827010|CRISPRCasFinder	6284702-6284738	37	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1393667-1393703	9	0.757
NZ_LT827010_15	15.1|6284702|37|NZ_LT827010|CRISPRCasFinder	6284702-6284738	37	NZ_CP024310	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence	708464-708500	9	0.757
NZ_LT827010_15	15.1|6284702|37|NZ_LT827010|CRISPRCasFinder	6284702-6284738	37	NZ_CP013054	Sinorhizobium americanum CCGM7 plasmid C, complete sequence	1017336-1017372	9	0.757
NZ_LT827010_15	15.1|6284702|37|NZ_LT827010|CRISPRCasFinder	6284702-6284738	37	NZ_CP023064	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence	528875-528911	9	0.757
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_014838	Pantoea sp. At-9b plasmid pPAT9B01, complete sequence	48074-48105	9	0.719
NZ_LT827010_10	10.2|3451527|36|NZ_LT827010|CRISPRCasFinder	3451527-3451562	36	NZ_LR594668	Variovorax sp. SRS16 plasmid 3	301753-301788	10	0.722
NZ_LT827010_23	23.1|8984709|32|NZ_LT827010|PILER-CR	8984709-8984740	32	NC_008243	Chelativorans sp. BNC1 plasmid 2, complete sequence	22502-22533	10	0.688
NZ_LT827010_10	10.2|3451527|36|NZ_LT827010|CRISPRCasFinder	3451527-3451562	36	NZ_CP015038	Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence	186428-186463	12	0.667

1. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP044544 (Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence) position: , mismatch: 3, identity: 0.885

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ctcggcgccggtgcggatcagggcgg	Protospacer
..***************** ******

2. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP027024 (Streptomyces sp. WAC00288 plasmid p2, complete sequence) position: , mismatch: 3, identity: 0.885

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccgccgccgatgcggatccgggcgg	Protospacer
 *** *****.***************

3. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP020556 (Streptomyces sp. Sge12 plasmid pSGE, complete sequence) position: , mismatch: 3, identity: 0.885

tccggcgccggtgcggatccgggcgg	CRISPR spacer
tccggcgccggtgcggatgcgggggt	Protospacer
****************** **** * 

4. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 3, identity: 0.885

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gcgctgccggtcctgcgcctgtcgcc	Protospacer
******** **** ***********.

5. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.885

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gccctgcccgtccagcgcctgtcgat	Protospacer
** **********.********** *

6. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.885

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gccctgcccgtccagcgcctgtcgat	Protospacer
** **********.********** *

7. spacer 1.1|316948|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP040819 (Paraoceanicella profunda strain D4M1 plasmid pD4M1A, complete sequence) position: , mismatch: 4, identity: 0.846

tcggagagctggtggtagagcgccat	CRISPR spacer
ccggcgagctgggggtagagcgccac	Protospacer
.*** ******* ************.

8. spacer 1.1|316948|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 4, identity: 0.846

tcggagagctggtggtagagcgccat	CRISPR spacer
acggggagctggtggtagagcgggat	Protospacer
 ***.*****************  **

9. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggctccgggcca	Protospacer
 *************** ******* .

10. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcgccggtgcggctccgggcca	Protospacer
 *************** ******* .

11. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggctccgggcca	Protospacer
 *************** ******* .

12. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_015951 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcgccggagcggatccgggggc	Protospacer
 ********** *********** * 

13. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_015951 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI01, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcgccggagcggatccgggggc	Protospacer
 ********** *********** * 

14. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP035419 (Leisingera sp. NJS204 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcggcggtgcggaaccgggcga	Protospacer
 ****** ********* *******.

15. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP038239 (Leisingera sp. NJS201 plasmid unnamed5, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcggcggtgcggaaccgggcga	Protospacer
 ****** ********* *******.

16. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggcgaggatccgggcgt	Protospacer
 **********.* *********** 

17. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP046575 (Rhodococcus sp. WAY2 plasmid pRWAY03, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
accggcgccggtgcggatcacggcga	Protospacer
 ******************  ****.

18. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to CP007643 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803b, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ctcggccccggtgcggatccaggcgg	Protospacer
..**** *************.*****

19. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcgggcggcggtgaggatccgggcgg	Protospacer
 * **** ***** ************

20. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcgggcggcggtgaggatccgggcgg	Protospacer
 * **** ***** ************

21. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP024873 (Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
tccggcgccggtgcgcttccgggtga	Protospacer
***************  ******.*.

22. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
cccggcgccggtgcggagcggggctg	Protospacer
.**************** * **** *

23. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcgggcggcggtgaggatccgggcgg	Protospacer
 * **** ***** ************

24. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MK937601 (Gordonia phage Charming, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

25. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976519 (Gordonia phage Tangent, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

26. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976510 (Gordonia phage Fosterous, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

27. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976518 (Gordonia phage Stultus, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

28. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH479924 (Gordonia phage Rofo, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

29. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MK937594 (Gordonia phage Galadriel, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

30. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MN329673 (Gordonia phage Jabberwocky, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

31. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MT723934 (Gordonia phage Love, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

32. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH651166 (Gordonia phage Angelicage, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

33. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MT639640 (Gordonia phage Paries, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

34. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MK977702 (Gordonia terrae phage McKinley, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

35. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_042108 (Gordonia phage Brandonk123, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

36. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976514 (Gordonia phage Nordenberg, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

37. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976508 (Gordonia phage Bibwit, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

38. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976506 (Gordonia phage Affeca, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
cccggtgccggtgcggaaccgggcag	Protospacer
.****.*********** ******.*

39. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MN329677 (Gordonia phage Keitabear, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

40. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MH976507 (Gordonia phage Ailee, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

41. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MT498035 (Gordonia Phage Barsten, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

42. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_031239 (Gordonia phage Vivi2, complete genome) position: , mismatch: 4, identity: 0.846

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggtgccggtgcggaaccgggcag	Protospacer
 ****.*********** ******.*

43. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 4, identity: 0.846

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gccctgcccgtccagcgcctgtccat	Protospacer
** **********.*********  *

44. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP025508 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvB, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggttgcgccggtgcggttccgggcgg	Protospacer
  . ************ *********

45. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP030764 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggttgcgccggtgcggttccgggcgg	Protospacer
  . ************ *********

46. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022667 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR2, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggttgcgccggtgcggttccgggcgg	Protospacer
  . ************ *********

47. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP050087 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b5, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggttgcgccggtgcggttccgggcgg	Protospacer
  . ************ *********

48. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggcttcgggcca	Protospacer
 *************** *.***** .

49. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_DQ996271 (Burkholderia glumae BGR1 plasmid pBGF3, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
cacggcgccggcgccgatccgggcgt	Protospacer
. *********.** ********** 

50. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

51. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_LR134455 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 13, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatgcggcggc	Protospacer
 ***************** ***  * 

52. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gtcggcgacggtgcgggtccgggcgt	Protospacer
 .***** ********.******** 

53. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgccgatccggccct	Protospacer
 ************* ******* *  

54. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

55. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

56. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

57. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggcttcgggcca	Protospacer
 *************** *.***** .

58. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

59. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP021127 (Rhizobium sp. Kim5 plasmid pRetKim5c, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
tccggcgcctgtgcgaatccggggtc	Protospacer
********* *****.*******   

60. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP020372 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs485, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
cctggcgccggtgcggatccggatgt	Protospacer
.*.*******************..* 

61. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

62. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

63. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

64. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

65. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

66. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

67. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggcttcgggcca	Protospacer
 *************** *.***** .

68. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP010859 (Marinovum algicola DG 898 plasmid pMaD4, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
cccggcgccggtgccgatccggccct	Protospacer
.************* ******* *  

69. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

70. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

71. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

72. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

73. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

74. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

75. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

76. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

77. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

78. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

79. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

80. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

81. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

82. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

83. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

84. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

85. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gcccgcgccggtgcggattcgggcca	Protospacer
 ** **************.***** .

86. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP011869 (Pseudonocardia sp. HH130629-09 plasmid pLS1-1, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtggggatccggcgcg	Protospacer
 ************ ********   *

87. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggcggcgctggtgctgatccgggcgc	Protospacer
  ******.***** ********** 

88. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to MN850588 (Escherichia phage sortregn, complete genome) position: , mismatch: 5, identity: 0.808

tccggcgccggtgcggatccgggcgg	CRISPR spacer
ggcggcggcggttcggatccgggcga	Protospacer
  ***** **** ************.

89. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 5, identity: 0.808

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gcgcagcccgtccggcgcctgcccga	Protospacer
**** ****************.*   

90. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP012916 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p2, complete sequence) position: , mismatch: 5, identity: 0.808

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gcgcagcccgtccggcgcctgcccga	Protospacer
**** ****************.*   

91. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.808

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gcgcagcccgtccggcgcctgcccga	Protospacer
**** ****************.*   

92. spacer 6.1|2214158|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032341 (Azospirillum brasilense strain MTCC4038 plasmid p2, complete sequence) position: , mismatch: 5, identity: 0.808

gcgctgcccgtccggcgcctgtcgct	CRISPR spacer
gcgcagcccgtccggcgcctgcccga	Protospacer
**** ****************.*   

93. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatcaggttca	Protospacer
 ****************** ** . .

94. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatcaggttca	Protospacer
 ****************** ** . .

95. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP006570 (Sodalis praecaptivus strain HS1 plasmid pHS1, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
aaaggcgccggtgcggatcccggcca	Protospacer
   ***************** *** .

96. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatcaggttca	Protospacer
 ****************** ** . .

97. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatcaggttca	Protospacer
 ****************** ** . .

98. spacer 5.1|1847624|26|NZ_LT827010|CRISPRCasFinder matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 6, identity: 0.769

tccggcgccggtgcggatccgggcgg	CRISPR spacer
gccggcgccggtgcggatcaggttca	Protospacer
 ****************** ** . .

99. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to MK937598 (Microbacterium phage Celaena, complete genome) position: , mismatch: 6, identity: 0.812

ccccggcaccggcctggaacacc--ccggccgcc	CRISPR spacer
ccccggcaccggcctggaactcctgctgaacg--	Protospacer
******************** **  *.*. **  

100. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 7, identity: 0.781

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
cctgcgcaccggcctggaacgccacggcaccc	Protospacer
**.  ***************.** ****  **

101. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 7, identity: 0.781

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
cctgcgcaccggcctggaacgccacggcaccc	Protospacer
**.  ***************.** ****  **

102. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NZ_CP020813 (Mycobacterium dioxanotrophicus strain PH-06 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.781

ccccggcaccggcctggaacaccccggccgcc-	CRISPR spacer
ttccggcaccggccccgaacacccc-cccgtcg	Protospacer
..************. *********  ***.* 

103. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_004808 (Streptomyces rochei plasmid pSLA2-L DNA, complete sequence) position: , mismatch: 7, identity: 0.781

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
ccgggccgccggcctggaacaccccgcgcgct	Protospacer
**  * *.******************  ***.

104. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.75

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
actgggcaccagcctggaacaccccggcgagg	Protospacer
 *. ******.***************** .  

105. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.75

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
actgggcaccagcctggaacaccccggcgagg	Protospacer
 *. ******.***************** .  

106. spacer 23.2|8984781|27|NZ_LT827010|PILER-CR matches to NZ_CP016620 (Microvirga ossetica strain V5/3m plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.704

agacccactggaacagcccgcaacagc	CRISPR spacer
gttcccactggaacagcccgcagggcg	Protospacer
.  *******************. .  

107. spacer 15.1|6284702|37|NZ_LT827010|CRISPRCasFinder matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.757

acggccacggccacccgaacccgcacccaccacgccg	CRISPR spacer
tcccgcgccggcacccgaacccgcaccaacgacgccg	Protospacer
 *   *.* * **************** ** ******

108. spacer 15.1|6284702|37|NZ_LT827010|CRISPRCasFinder matches to NZ_CP024310 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3c, complete sequence) position: , mismatch: 9, identity: 0.757

acggccacggccacccgaacccgcacccaccacgccg	CRISPR spacer
tcccgcgccggcacccgaacccgcaccgacgacgccg	Protospacer
 *   *.* * **************** ** ******

109. spacer 15.1|6284702|37|NZ_LT827010|CRISPRCasFinder matches to NZ_CP013054 (Sinorhizobium americanum CCGM7 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.757

acggccacggccacccgaacccgcacccaccacgccg	CRISPR spacer
tcccgcgccggcacccgaacccgcaccaacgacgccg	Protospacer
 *   *.* * **************** ** ******

110. spacer 15.1|6284702|37|NZ_LT827010|CRISPRCasFinder matches to NZ_CP023064 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631b, complete sequence) position: , mismatch: 9, identity: 0.757

acggccacggccacccgaacccgcacccaccacgccg	CRISPR spacer
tcccgcgccggcacccgaacccgcaccgacgacgccg	Protospacer
 *   *.* * **************** ** ******

111. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_014838 (Pantoea sp. At-9b plasmid pPAT9B01, complete sequence) position: , mismatch: 9, identity: 0.719

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
cggtgaaaccggcctggaacaccgccgccgga	Protospacer
*  .*. **************** * ****  

112. spacer 10.2|3451527|36|NZ_LT827010|CRISPRCasFinder matches to NZ_LR594668 (Variovorax sp. SRS16 plasmid 3) position: , mismatch: 10, identity: 0.722

aagatcgctgccgacgagcagcgcaaggcgcacgag	CRISPR spacer
tgcctcttcgccgacgagcagcgcagggcgctcgat	Protospacer
 .  ** ..****************.***** *** 

113. spacer 23.1|8984709|32|NZ_LT827010|PILER-CR matches to NC_008243 (Chelativorans sp. BNC1 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.688

ccccggcaccggcctggaacaccccggccgcc	CRISPR spacer
cgacggcagcggcctggaacatcccgaggctt	Protospacer
*  ***** ************.****.   ..

114. spacer 10.2|3451527|36|NZ_LT827010|CRISPRCasFinder matches to NZ_CP015038 (Burkholderia cenocepacia strain 895 plasmid pBcp895-1, complete sequence) position: , mismatch: 12, identity: 0.667

aagatcgctgccgacgagcagcgcaaggcgcacgag	CRISPR spacer
cgcttcgatgacgacgagcagcgcaaggcgtttcgt	Protospacer
 .  *** ** *******************. . . 

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2333775 : 2384758	49	Bacillus_phage(37.5%)	tail,plate,transposase	NA
DBSCAN-SWA_2	6501598 : 6545938	55	Paenibacillus_phage(100.0%)	transposase	NA
DBSCAN-SWA_3	6859610 : 6922095	58	Acanthamoeba_polyphaga_mimivirus(20.0%)	tRNA,integrase,transposase	attL 6856817:6856834|attR 6924284:6924301
DBSCAN-SWA_4	9045686 : 9090307	32	Hubei_virga-like_virus(16.67%)	transposase,protease	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_LT827010|2333775:2384758|DBSCAN-SWA
GATGCGAATGGTGTACGGGGACGACAGTGTGCGATCGCCGCAGGAGACCCGGGTCTCCGCATTCGTCGACGAGATGTTCGGTGATCTGGGCCGGGCCGATCAGCGCCGGTGGGCGCGAATCTATCTCCGGGGAATGCTCACCGCACGCGGCAAGAAAACCGTTCAGGAAATAGCCCGCTCGGTCGGCGCGGAATCTTTCGTCGCGCGCGGCCTGCGCCAGTTCATCAATTTCAGCCCGTGGGACTGGGGCGGTCCGCGGCGCCGGCTCGCCGAGATGCTCTGGGACGCCGCGCCCGGGCAGGCGCTCACCGTCGCGGTGTCGGCGATCCCGAAACGCGGCTCGCAGAGCGTCGGGGTGCAGCGCCGGTTCGTCGTGGCGGCCGGCCGCACGGTCAACTGCCAGCTGGTGGTGAGCCTGTTCCTGGCCACCGGGCGGCAGCTGGTGCCGGTGGACTGGGAGCTGGTGCTCGGCCCGGAGTGGGGCGCCGACCGGGCCCGGCGGGCCCGGGCCCGGATCCCGGACTCGGTCGAGGCGCGACCGGTGTGGCGGCACGTGCTCGACGTCGTGCGGCGATCGGCCCGGTTCCGCGCCGGGCTGCCGCTGGTGGCCGACCTGAGCGAGCTGGACGAGGTGTGGCCGCTGGTGGTGGCGCTGGCCGGACGCCGGGAGCTGGTCATCGCGGTGTCCCCGGGCCAGCGCATCCCGGCGTGCCGGGCGGGCCGGCCGGGGGACGGGACCTCGCCGACGGTAGGCGAGTTGCTGCAGGCCGCGGCGGCCGGTCGGGCCCGGCACAGCGTCACCGTGCCGGACCCGGACGGCACGCCGCGGACGGTGGCGGTGCAGTCGGTGGCGCTGCGTGGCGGCCGGGGCGCCGACCTGTGGCTGCTGGGCGAGTGGTCGCCGGAATCCCGCCGGTTCACCCGGTACTGGCTGACCAACCGGGCCGACCGGCCGGGCACCACGCTGGAGCTGGGCCGGTACGCCGACCGGACCGCCGGGACACTGGCCGAACTGCGCCGGGATTTCGGCGTGCTGGATTACGAGGGACGCTCGTTCCCCGGCTGGCATCACCACATGACGATGGTGTCCGCGGCGTACACCTTGCAATTGATTGATGTCTGCTCGGCCGTTCTGCAGGCCGCCGGGGCAGTTTTTCCCGGAACGATTTGACGAAGTCGCCGTTTCTTTCCCCAACGGATCGGCGCATGCTTTTCCTATCACTTTCCAAACCTTTTCCCGATGGTGAGGTGATTCGTCGTGCTGTGGGAACCCCCCGAGACCGGGGAACAATCGGAATGGCTGTCCCGGGTGGCGGCGCTGGCGCCGCTGATCGAACGGCACCGCGCCGAGGCCGACCGGGAGCGCCGCACCCCGCAGGCCGTCTTCGAGGCGTTGCGCGACGCCGGGATCCCGCGGATGTGGGTCTCCACCGAGTTCGGCGGCGGCCAGGTCGGCCTGCACACCGGATCGCTGGTGATCCAGGCGCTGGCCCGGCTGGACGCCTCGGTCGCCTGGCAGATGGGTGTGCAGGGGGCGATCGGCCGGATCTCCGACTACCTGCCCGAGCAGACCGCCCGGGAGCTGTTCAAGCAGAGCGGCGGTCTGGTGGTCGGCGCGGTGAACCCGGCGGGGCGGGCCGAGGAGACCGCCGGCGGGTACCGGATCAGCGGCCGGTGGGGCTTCGCGAGCGGCTCGGCGTTCGCCGACTGGCTGGTCTGTGCCGCGCCGGTGCACCGCGACGGACAGCCGGTGCTGCGCGGGTCCGCGCCCGAGCTGCGGATGCTGTTCGTGCCGGTGTCCGCGGTCCGGCTCCTGGACAACTGGCACACGCTGGGTCTGCGCGGCACCGGCAGCAACGACTTCGAGGCCGACGACGTCTTCGTGCCGGCCGAGTACACGGTGGACCAGGCGGCGATGCTGCGGCCGCCGGCCGGCCGGTTCTCCCGCGCCTACCCGATCGGCTACTACGACTTCGGCCCGTTCACTTCCGCCTCGACCGCCGCCGGGGTGGCCCGGGACGCCGTGGCGACGGTGACCGAGCTGGTCCGCGGCAAGGTGCAGACCGGCGGCTCGGGCAGCCTGGCCCGTAGCCACGTGGTCCAGGACCGCCTGGCCCGGGCCACCATGCACGTGCACACCGCGCGGACGCTGCTGCGGGACACCGCCGAGCGGGTCACCGAGTCCGGTGAGAGCGGCGGCGAACGCCTGACCGCCACCGTCCGGCTCACCGCGGCCACCGTCGCCGAACTGGCCGTGCAGGCCGTGGACATCGCGTACGACCTGGCCGGCTCCACCTCGCTCTATGAGACCAGCCGGCTGGAGCGGGCGTTCCGCGACGTGCACTCGGCGGTCAAGCACATCACCCTCGCTCCGCAGCACTTCGAGATGGTCGGCCAGTACCTGGTCGGCGGCGAACTGCGCGTCCGCCGCTGATCTCTTCCGCTTCCCGAAAGGACCCCGCAATGCCGAACATGAAGGCAGTTCAGCTGCTCGCACCGCGCAAGACGGTGCTCGCCGAAGTGCCGGTGCCGGCGACCCCGGCCGACGGCCTGCTGCTCAAGACCCGCTGTGTCTCCATCTGCTCGACCGACATCTCGTTCTTCGAGGGTCACCTGTTCCCCTCCGAGTACCCGGTGATCCTCGGCCACGAGTACCTGGGCGAGGTCGTCGACATCGGACCCGAGTTCGACGGCGGCGGTGTCGACGTGCGGATCGGCGACCGCATCGTCTACTGGGGGCAGACCGACTACGGCGGCTTCGCCGAGTACCGCAGCCTGCGGCCGATCTTCTCGGGCCAGATCCTCGAGGACGTGTTCTGGGCCGACCGGCACTTCTTCGACGACGACCGGGCCGCCGCGGTCAAGGTGCCGGACGACCTCAGCGACCTGGAGGCCTCGTTCATCGAGCCGACCACCGGCGCGCTGCGCTCGGTGCTGACCAACCCGCCGCAGGTCGGCGACCGGGTGCTGATCCTGGGCACCGGCCCGATCGGGATCATCGCGGGCAGTGTCATCCAGCGGCTGCTGGCGCCGAACCGGATCGTCTCGATGGACGCCAACCCGGCCCGCAACCAGCACGCCGAGGAGCACTTCTCGCAGCACGCGTATCTGCCGCACGAGCTGATCGACACGGTGCCGGAGAGCACCTTCGACTACGTCTTCGACACGCTGCCGACGATCAGCGGAGTGCCGGAGGAGAACGACCCGCGCCGGGTGGCGATGCGCAAGCTGAAGCCGGGCGGCCACTACGTGCTGTACGGGGCGTCGCAGGAGATGCAGAAGTTCGACACCTGGCTGATGCTCGCCAAGGGCATCCGGATCAGCGCCGCGCCGTTCGACGTGACGCACTTCCCGATGCACAAGACCGCCAACGTGATCACGTCGGCGATGCAGATGCTGCGTTCCCGGATCGTCGACGGCCGGCGGCTGCTCTCCCACGTCTGCCGGTTCGACGACTACGACGGCCTGGTCGACGTGCTGGAGAACTACCGGCACACCACCAGCCTGAAGACCATCGTCGACTTCCGCTAGCGGCCGGGGGCCGGGCTCCGGCCCGGCTCCCGCCGCCCCCGAGGAAAGAGGAGAGTCGATGGAGCAGCGATCGTACGACGCCCGCTTCGTGGTCGTCGCCAATCGCCTGCCGGTCCAGTCCCGGGTGGCCGCGGACGGTGCCCTGCTCTGGGAGCGCAGCCCGGGCGGCCTGGTCAGCGCCCTCGAACCGTTCCTGAGCCGGCGGCACGGTGCCTGGGTCGGCTGGCCCGGCGTCGCCGGCGTCGACGTCGCGCCGTTCACCGACGGCGGCACCACCCTGGTTCCGGTCCGGTTGAGCGAACAGGACGTCCGGGACCACTACGACGGGTTCGCCAACGCCACGTTGTGGCCGCTGTACCACGACGTGGTGGTCCGGCCGACCTTCGACAGCCGCTGGTGGGCCGGGCACGTGCGGGTCAACGAGCGGTTCGCCCGGGTGGCGGCGGAGACCTGCGCGCCGGGCGCCACCGTGTGGGTGCACGACTACCAGTTGCAGCTGGTGCCGGAGATGCTCCGCCGGCTCCGGCCCGACCTGCGGATCGGTTTCTTCCTGCACGTGCCGTTCCCGCCGGTGGAGCTGTTCCAGCAGGTGCCGTGGCGGGCCGAGATCCTGCGTGGGATGCTCGCCGCGGACCTCGTCGGTTTCCAGGTCCCGGCCGCGGCGGTGGGGTTCGCCGAGGCGGCCGTGCGGTTCGCCGGGGCGCGCCGGGCCGGTCCCGGGTCGTTGTTCGTCGAGGATCGGGCGGTACGCGTCGACGCCTTCCCGATCTCGGTGGACGCGCCGGCCTGGGACCGGGTGGCCCGCCGCCCGGAGGTCCGCCTCCGGGCCGCGCAGATCCGTGCCGAGCTCGGCGACCCGGCCCGGGTGGTGCTCGGCGTCGACCGGCTCGACTACACCAAGGGCATCGACGTGCGCCTGCGGGCGATCCACGAGATGCTCGCCGACGGCCAGATCAAGGCCGCCGACACGGTGGTCGTGCAGATCGCCAATCCGGCGCGGGAACGGGTGGACCAGTATCGGGCGGTGCGCGACCGGGTGGAGCGGCTGGTCTCCGCGGTCAACGGCGACCACGGCCGGGTCGGCCGCCCGGTGGTGCACTACCTGCACACCATGGTGGACCAGGCCGAACTGGCCGCCTTCTACCTGGCCGCCGACGTGCTCACGGTGACGCCGCTGCGCGACGGCATGAACCTGGTGGCCAAGGAGTACGTGGCCAGCCGGCACGACGGCGGCGGCGTGCTGGTGCTCAGCGAGTTCGCCGGCGCGGCCGCCGAGCTGCCCCAGGCGCTGCCGGTCAATCCGCACCACGGCGACGACGTGAAGGCGGCGTTCCGCCGGGCGCTGGAACTGGATCCGGCCGAGGGCGTGCGCCGGATGCGGGCGATGCGCGAGCACGTCTTCGCCCATGACCTGACTGACTGGGCCCAGGCCTTCCTGGCCCGGCTCGACGATCCGGCGGGAGAGGGGTGACCGCGATGTCGGTGACCACGTCCGACTTCACCAGTCTGATGGCCCGGGTGCCCGGGCCGGTGGTGGTGGCGACCACGGTGGACCCGGACGGCCGGCGGTGGGGTTTCACCGCCAGCGCGTTCAGCTCGCTGTCGCTGAGCCCGCCGCTGGTGCTGCTCTGCCTGGCGAAGTCCGCCAGCACGCACGCCGCGTTCGTGCGCGCCGAGCGCTTCCTGGTCAACGTACTGGCCGCCGATCAGGCGGCGGTGGCGGCCCGGTTCGCCCGCTCCGGCGAGGACCGGTTCGCGGCCGGCGACATGCGGCCGTACGAGCTGGGTCTGCCCGGTCTGCCCGGCGCCGCGGCCCGGGCCGCCTGTGCCCTGGACAGTGTCCTGGAGGGCGGCGACCACAGCATCCTGGTCGGCCGGGTGCTGGCGGTCACGGTGGCCGAGCCGGCCCCGCTGGTGCACTGCGACCGCGCTTTCGCCCGGCCGGTGCCGCTCGATCAACTCGCGGTGGCCCGGTCGCGGTAGGCGGTCCCTTGCGCCTTGCCGGTGCCGTTCGGTCAGCCTGCGGTGGCCCGGTCGCGGTAGGCGGTCTTCTTCGCCCGGTTGCCGCATGCGCTCATCGCGCACCAGCGCCGGGTGCCGGGCCGCGAGTTGTCCACGAACAGCGCGCTGCAGGCCGGGTCGGCGCACTCCCGGATCCGGCTCGCGGCCGGCGTGGTGGCCAGGTCGAGGGCGTCCCGGGCGACCAGCGAGAGGGTGGCGGCGACCGGGTCGCCGGCGGTCCAGTCCAGCGTGCCGGCCGGCTGGACCGCCGGGATCGGCGGTGGTGCCGCGGCGATCCGGTTGACCAGGTCCAGGTCGGTCGCCGCGCACCCCGCCGGTCCCTTGGTGACCAGGGTGAACACCGCCTCCCGAAAGCGTTGCACGTCGGCCGGCGGAAGGCTCGCGACGGTGGCCGGCACCGGGCCGAACTGCGTCACCCAGGCGAGGACCGCGGCCGGGGTGGGCAGCTCCTCGACGGCGTCGGGATGGCCGCGACGGCGCAGCGTGCGGGTGAAGTCCAGGCACAGGCGCCCGGCGCCTTGACGGAACGGTTCGGCTGCCACCCCTGCACCGTATCTCAGGAACCGGTTTGACCCGTTCCCCGGGAACCGGTTATATAGGTTCCATACCCACTTACGAGGAGTTGTCGTGACGGACCTGAAGTCATCCCCGGCGCCGTCTCGCCGGTTGATCCTGCTCATGGCCCTGGCCTGCGGCGTCGGTGTGGCCAACGTCTACTTCCCGCAGGCGATCACCCCGCTGCTCGCCCGGGACCTGCACATCTCGGAGAGCACGGCGACCACCGTCGCGACCATGGCCCAGCTGGGCTACGCGGCCGGGATCTTCCTGCTCGTCCCGCTCGGCGACCGGCTGCCCCGCCGCCGCCTGATCGCCACCCTGTTCGGCGTCGTGGCGGCCGGCCTGTTCCTGGCCGGGATCTCCTCCTCGGTGCCGCCGCTGCTCGCGTTCTGCGCGATCGTCGGCGCGGCCACCGTGGTGCCGCAGATCCTCATCCCGATGGCCGCCGACCTGGCCGGGCCGACCAGCGCCGCCGGCACCGTGGGCATCCTGCAGGGCGGCCTGCTCGGCGGGGTGCTGCTGGCCCGCACCTTCGGCGGCACGCTCGGCCAGCTGCTGGGTTGGCGCGCGCCGTACCTGATCGCCGCCGCGCTCGCGGTGCTGCTCGCGATCGCCCTGGTGGTGGCGCTGCCGGCGACCGCACCCTCGTCGACCGAGCGGTATCCCGCCCTGCTGGCCACCTCGCTGCGGCTGCTGCGCACCCAGCCCGCCCTGCGGTGGTCCTGCCTCTACCAGTTCCTGCTGTTCGGCGCGTTCACCGCGGCCTGGACCAGCATCGCGCTCCACCTCACCGGACCGGCGTTCGGTTACGGCACCAGCGTCGTCGGCCTGGTCGCCCTGGTCGGCGCGGCCAGCGTCTTCGCGGTGCCGGTGGCCGGCCGGCAGATCGACCGGCGCGGGCCGGACGTGATCAGCGTGCTCTGCTTCGGCGGCCTGCTGCTGGCCGCGGCGGTGCTGCTCACCGGGACCTGGCACGGCGTGCCCGGCCTGATCGGGCTGACCGCCGGCATGCTGCTGCTCGACGTGTCGGTGCAGACCAGCCAGGTGGCCAACCAGGCGCGGATCTTCGCCCTGGTGCCGGGCGCCCGCAGCCGGCTCAACAGTGTGTACATGACCGCCGTCTTCCTGGGCGGCACCTGCGGCTCGTGGGCCGGCGCCCGGATCTACCTGCACTTCGGCTGGGGCGCGGTGGCCGCGCTGGTGGCCGTCGCCGGGGTGGCCGCCCTCGCCGGGCACCTGCTGCGCCTGCGGATCACGGCGCCGGCCGGCCGCCGGGAGTCGGCGGAGGCCGCCGCATGATCTGGTTCGTCACCGGCGTCCCGCGTGGCTTCGGCCGGGAGTGGGCGGAGGCCGCCGCATGATCTGGTTCATCACCGGCGCTTCCCGCGGTTTCGGCCGGGAGTGGGCGGCCGCGGCCCTGCGCCGCGGCGACCGGGTGGCCGGCACCGCCCGGCAGCCGTGCGACCTGGCCGGCCTGGCCGAGGAGTTCCCGGAGACGTTCCTCCCGCTGCGGCTCGACGTCACCGACCGCCCCGCGGCGGTCGAGGCGGTGCGCCGCGCCGCCGCCCACTTCGGCGGTCTCGACGTGGTGGTCAACAACGCCGGTTACGGCCACTTCGGCATGGTCGAGGAGCTCGCCGAGGAGGAGATCCGGGCCCAGCTGGAGACCAACGTGCTCGGCCTGCTCTGGGTCACCCAGGCCGCGCTGCCGATCCTGCGGGTCCGCGGCGGCGGGCACATCATCCAGGTGTCCAGCATCGGCGGACTGGTCGCGTTCCCCGGCCTCGGGGCGTACAGCGCCTCCAAGTTCGCGGTCGAGGGGCTCACCCAGTCGCTCGCCCAGGAGGTGGCCGCCCAGGGCATCCGGGTGACCCTGGTGGAGCCGTCCGGGTTCCGCACCGACTGGGCCGGCCGCTCCGCCCGGCACAGCGCCGAGTCCCCGGAGTACGACCTGGTCCGCGCGGCCCGCGACCGCCGGCCCACGGCCCGCCGGGTGGGCGACCCGCGGGCCAGCGCCGCCGCCCTGCTGGCCGTCGTGGACGATCCGCGGCCGCCGCTGCGCGTCTTCTTCGGCAGCGCGCCGCTGGACATCGTCACCCGGGAGTACGAGGACCGGCTGGAGACCTGGCAGGCGTGGCAGCACCTGGCGGTCGCGGCCGAGTCCTGAGCGTGCGCCCCGGGCTCATCCGGGGACGCCGGCCACCTGCCGTCCGGCCGTCGCCGCCGTGGTCGCGGCCGGCGGCTGGGCGCGGCGGGTCAGCAGGCCCAGGGTCAGCGTGCTGACCACCATCAGGGCGCCGGCCAGCAGGAACGGGGTGCGCAGGCCCAGCCAGTGCGCGACCGCGCCACCGGCCAGCGCGCCCAGCGGCAGGGAACCGAACCCGATCAGACGGTAGATGCCGGTCACCCGGCCCATCAGGGCGTCCGGGGTGATGCTCTGCCGCAGCGACCGGCCGACCACCGAGAACGACACCCCGGAGAACCCGGCGAGGAACTGGCAGCCGACGATCACCGCGACCGACGTGGTGCACGCGATGCCGAGGGTGACCACGCCGGCCACCAGGCTCGCGGTGATCATGGTGCCGAGCCGGCCGAGCAGGCGGATCGTCCACGGCGAGGCGACCGCGCCGGCCACGCCGCCGATCCCGGCCCCGGTCAGCAGCAGGCCGTACGCGCTGTCGCCCAGGTGCAGCCGCTGCACGACGTACAGCACCAGGGTCGCGTTCGCGGCCGCGACCCCGAGGTTCATCGCGGTCGCCCAGAGCGCCTGGGCGCGCAGCGACGGGTGGTGGACCAGGTAGCGGAAGCCCTCCCGGGCCTCGGCGGTCAGCGACGGCCGGTCGCCCGGCGGCGGCGCCACCCGGCCCGGCACCCGCAGCCGGGTCAGCACCGCCCAGCTGCCGCCGATCGCCGCGGCGAAGACCGCGAACGGCGCCGCCGGGCTGAGCGAGAACAGCAGGCCGCCCGCGGCCGGGCCGGCGAAGTCCTCGCCGATCGACTGGGCGGCGGTGAGCCCGGCGTTGAGCCGTTCCAGCCCGGCGTCGCGGACCACCACCGGGGTCAGCGACTGCACCGCGGTGTCGGCCGCCAGCTCGGCCGCGCCCAGCAGAAACGCGGTCACCAGCAGCAGGGGCAGCGACGCGGTGCCGGTCAGCACCGCGCCGAACAGCACCAGCACGACGGCCAGCCGGGTGAGCTGCATCGAGCGCAGCAGCCGGACCCGGTCGAACCGGTCGACCGCCGCACCGACGTGGAAACCGAACAGCAGGTGCGCGGCGGACAGCGCGGCCGAGACCGCGCCCACGCTGATCGGGTTGGTGGTCACGTGCACGGCCAGTAGCGGGAAGGCGGCGTAGCGGATGCCGTCGCCGAGGCTGGCCGAGGCGCCGGCGGCGAACAGCGTGGGAGCCGGATGCCACCTCATGACGCGGTCCAGACCGGCGACGGGGCGTACCCGCTGAACGGGTTGATGTTGATGGTGCCGGTGGCGTTCACCGCGTACCGGCGCAGCACCGCCACCGCCCGCCCGTCCACGATGAAGACACCGTTCACCGACGGTGTCTCGGTGACCGTGGCCCGGCCGGTCGCGTCGGTGAACGCCACCGGCAGCCGGTCCGGTTCGAAGACCTGCTGGACGATGTACGGGTGGTCGCCGGCCCCGCCGCGCACCCCGGCGCCGACCGCCTCGGCCCACGCCCGCGCCGACACCTCGCGGCCCACCGTGATGCCCTTGCCGGCGTGCCCGCGCACCGGTTTCACGATCAGCCGTTCCCGGTTCGCGGCCACCCAGGGCAGCAGGTCGACGTCGGCGCCCTCGACGGTGGTCCGGCGCGGTTCCAGCACCCGGGTCCACGGTACGTGCGCGGCCAGCCGGTCGCGCAGGTCCGCGTCGAGCCGGTCCACCACGGTCTCGTCGGAGAGCACCGCGAGTGCCGCCTTGGACGCCAGCACCTCGGCGCGATACCCGGTGAACAGCCCGACCAGGCCCGCGCCGGCCAGCGCGAACAGCTGCTTGAGCAGGGTGAACTCGTCATGTTCGGTGGGTTCCGGCGATTCGAAGTAGCGGTAGATCACCTGCACCGGGCGCCCCTGGTAGGCGACGCCGGCGTCATCCATCCGCAGATCCTCGAGCGCGCAGTGCACCGCGTCGACGCCGTGCCGGCGCAGCTCGCGGGCGAACAGCTCGTACTGCCAGTCCAGCGGCCCGGCCTGCTGCTCGTGCCGCCAGTAGCAGATCGCCACCGTGCCGGTCAGCCGGCCGAAGCTGCGTTCCAGGCTGTCCAGCAGGCCGCGCATCGCCACCGCGGGGCGGGCCGGGGCCTGCGGTGCCGGCCGCTGGAACGCCGCCTGGGCGCGGGCGATGATGTCGTGCAGGCCGAACAGCCCGGCGGGGGAGTCCCCGTTGATCTCGACGACGACGGTCCGGCCGCCGGAGCTGATCACGTCCGGGCGGGCCACCGTCGACCAGTTCTGATCCGTCTGGTGGGTGAGGAACTGCAGTTCCGGCTCGGTGGCCCGGCACAGCCGCGCCATCCGCAGCACGTCGCCGCCGCAGACCTCGCGCAGTACCGCGTCCAGCCCCTCGAAGACGGTTTGGCAGGCGGCCTCCAGCCGGCGCACCTGTCCGGGCGACTCGACCGGCGGCCGGAAGATCAGCCGCTCCCGGGCGTACGGCGCGTTCAGCTCGCGCAGCTCGGTGGTGGCGGCCCGGAACTCCTCGGCGGTGGGCTGCGTGAACGGCGCGGTCACGACTCCTCCGTGAACTTGCGGATCAGCGCGTGGGTGGCCGCCGGCGCGTCCCAGACGGCCTGGTGGCTGGCGCCGGGCACGACGTGCAGCTCGCCGGCGCGGCCGGGCAGGCTGTCCACGATCTCCTCGGCGACCGCGTACGGGATGAGCGGATCGTGCTCGCCGACCAGGACCATCACCCGGCACTTCGCGGCGGCCAGATCGGGCCGCAGGTCGAGCCGGTCGAGCTGGGCGATGAACCCGGCGTTGATCTCCGGAGTGGTGATCCGGTCCCGGAGCACCCGCTGGTACGCCTCGTCGGGCGCCCGCCGGATCGCCAGCGGCCCGCAGACCTCGGCCCACTCCCGCTCGGCCTCGGGCGAGTGGTCGGTCAGCGACCGGCGCATCACCGCGGCCGCACGGTCGCCGCCGAGCACCCGGTGGCGTTCCACGATCTCGTCGTGGCTGGCCTGCCGGGCGCCGGTGCCGATCAGGATCGCGCCGCCCGCGAGCTCCGGGTGCCGGCCCAGGAACCGCTGCACCACGAACCCGCCGAACGAGGTGCCGAGCAGGTACGGCTTCTCCAGGCCCAGCGTGTCCACCAGCGCGGCCAGGTCGTCGGCCCAGGTGTCCAGGGTCCACTCGGCCGGGCCACCCCGGTCGCTGCGCCCGTGACCGCGCAGGTCGGGGACGATGACCTGGGCGTACTCGGCGGCCGGCAGCATGGTCAGGCGCAGCATGGTGCCGTCGATGCCGGGGCCGCCGTGCACCGCGATGATCGTGGGCCGGTGGACGCCGTCGCGCCAGTCGTCACCGATCGTCGTGACGTGCAGGCGTACTCGTCCGGCGCGGACTCTCATCGGGTTGTTCCCTTCCTCGTCATGCGGGACGGCCGACGCCCAGGGCGAGGCCGCGCGGATACAGGGTGGAGCGGGTGTCCAGGGTGACGGCGTCCGAGGTGTCGGTCAGGCGGTACCGCCGGAACACCCGGACCGCCTCGACGAGCTGCGCCTTGGCCAGGTGGGTGCCGACGCACCAGCGGGGGCCGCCGCCGAACGGCAGGTAGGCGCCGGCCGGCAGGCGGCCGTCGCGCCAGCGCGCCGGCCGGAACGCCGCCGGGTCCGGAAAGTGGCGCTCGTCGCGGTGGATGGCATAGGGGCAGATCATCACGGCGGTACGCGCGGGGAACCGCCAGTCCCCGCTGATCTCCTCGCCGTGTGTGGTGCGGTGGATCAGCCAGGTGGGCGGCCAGAGGCGCAGCACCTCGTCGACGATGTGCGCCGGCTCGTCGTCCGGCTGGTGCACGGCCAGCGCGCGCAGCGTCCACGCGGTCGCGGCGGCCGGCACCAACCGCCCCGCGATGGTGGCCGAGATCAGGATCCGGACCAGCGGCTCACGCGGCACCCCGGCGTCGCGCAGCGCCGCGACCAGCCCGCCGGACGGGGCCCGGTCGACGAGCGCGCCCAGGCTCTCCGCGAGCCGGTGCTGGGCGCGGACGGCGCGGCGCCGGCGTGGGGTGAGCCGGTCGAGGAACCAGGGCAGCTCGTAGGAGGAGCCGACGATCGGCGTGAGCGAGTCCAGCAGTCCGGCGACGGCGGCGGCCGGCTCGCGCCGGTCGGCGCCGCGACTCGACGGGCCGGCGCACAGCCGCAGGAAGGCGTCGGTACTCAGCCGCACCAGCGGGGTCAGCGGGTCGCCGGTGCCGCCGCGCGCCGCCCACGCGTCGAGCAGCCCGGTCAGCTCGCCCGAATACCAGCTCAGGTGTTCGGCGACCAGACCGCCGGAGAGGGCGGACAGCATCGCCCGGCGTGCCGACATCCAGCTCTCCAACGCGTCCTCGCCGCGCCGGCTGCCGGTGGGCCGCCACGCCCGGTCGCGGTCCATCAGGAAGTCCCGGTTGGTGCGGCGCAGCACGTCGTGGGCGACCTCGCCGTCGGCGACCAGCACGGTGCCGGGGCTGAGCTCGGTCACCGGGCCGAACCGGCGGACCGCGTCCATCACGAAGCCGAGCCGGTCCCGGTCGTACTCCTGGATCAGGCCGGCCCGGGACAGGTTGGCCGGGACCGGCGGCGCCGTGGTCACTGATCTGTCCTCCCGTGTCGGTGGCGGCCGGTGACCCCGCGGGGTCACCGGCCGCCGATCACCCATCTCAGTGCCAGGGGTACGCGCCGGCCAGGGCCTTACGCGCGAAGCGCGCCTTGATGCGCTGGATCATGTGGTCCACCTCCTCTCCCCGTGAACGATGGCGGTGGCGGTGCCACCAGGTCCGCGGGGACCGCGCGCAGCGCGCGCAGTCCCGTCTGCCGGGCGACGTCGAGCAACTCCGCCCGCAGCAGTTCCAGCACGGCGAGCACGCCGTCCTCGCCGTCCAGGGTCAGGCCCCAGACGTACGGCCGGCCCAGGCACACCGCGGCCGCCCCGGCCGCCAGCGCCTTGACCACGTCGCCACCGGTGCGGATCCCGCCGTCGAGCAGGACCGGCAGCCGGCCGGCGGCCGCGGCCACCACGCCGGGGAGCGCGTCGATCGCCGCGATCGAGTCGTTGAGCTGCCGCCCGCCGTGGTTGGAGACGATCAGGCCGGCCACCCCCCGATCGGTGAGCAGCGCCGCGTCCGCCGGATGCAGCACGCCCTTGACCACCACCGGCAGGCGGGTCTGCGACCGGATCAGGTCGAGCAGCTCCCAGGTCAACGGCCAGCGGGGCAGCCGGGTGTCGGGCGGCACCGCGCCGTCGGAGAAGCCGCTCTCCCGGTGGATGCCGAACTCCACCTCGGGCGGGGTGGCGAAGCCGGACCGCAGCATCGCGACCCGCCGCGACGGGTGGCTGTTGTCGATGGTCACCACCAGCGCCCGGGCGTCCACGGACTCGGCCAGCCGGATCGTGCGCACCACGTCGGCCCGGCTGCCGTAGCAGTACAGTTGGAACCAGCACGGCCCCTGCTTCGCGATCTCGGTGAGGCTGTGGTGGCTGTCGTTGCTGACGATCGGCAGCACCCCGGCCCGCCGGGCGGCCCGGGACACCGCGAGCTCGGCGTCCGGATGGAACAGGCGCAGCGGGCTGGTCGGCGCGAGCAGCACCGGCATCGCGGCGGGGAAGCCCAGCACGTCCACGGTCAGGTCCGGGTCGGCGACGCCGTTCAGTGGGCGGGGCCGCAGCCGCAGCCGGCGCAGCGCCGCCTCATTCTCCCGGACCGCGTCGTCGTGACCGGCGCCGCCGGCCAGGTAGGACCACCGGGCCGCGTCCAGCACGCCCTGGCAGGCCCGCCGGAAGTCGTCGAGGTCGAGCATCCCCGCGGTGTTCATCCGCGCCCCCGGGTGAGGTCGTGCCGCACGTAGGTGCGCAGCAGCCACCGGTCGTGCCCGTCGTAGTGCGCCTCGAAGGCGTCCCGGCCGTGCAGGCACCGGCTGTTGGAGAAGGCCAGAAAGCTGCCGGGGGCGAGCCGGACGAGGTGTTCCTCGCGGTCGGCGGCGGCCTGGAACTCCGCAATAGCGCATTGATCGACGTCGTCGACACCGGTTATCGAACTGTGCCAGCGGATGGTCGGCTGGCGCAGCGTACCGCCCATCGGAGCGACATTTTCCGCGACGGCCTGACCGGGCGAGAAACTGTCCGGGGCGTTGATTCGGAATTGTGGCCGGCGCAGCCGCTGCACGGTTTCCGGGGAGCAGTTCCGGACGGCGTCGGCGACCCGGACGAGGCGGGTCGCCGGGCGCGGCTCGGGGCTGCGGACGCCGTACAGCAGCACGAAGTCGGGCCGGACGTCGTGGAACGCGATCTCGGTGTGCAGCCGCAGATCCACCGCGGAGGAGGCGTTCGACTGGGTGGCGGCGCGGTCGGGCCGCGGCCGCACGTGGTGCACGAGGGTGCCGTTCTGCTCCGCGGGATACCCGAACTCGTGGCCGAGTTGCCTGGTCAGCATGCCTAGCCAGGTCAGTCCGAGCAGCGGCGGCGCGTCGGCGTCGGTCGGGTCGGCGGGCAGCCCGTGTGCCACCACCGCGTCGAGGCTGCCGGCCCGCAGTCGGGCCAGCGCCTCGCGGAGCCGGGCGGGCAGGATCCCGGCGTGCCGGCCGGCGCGCCGGAAACAGTCGCCCGGCGCGCCGGTCCCGGTGATCTCACGCCGGGCCCGCCGCGCCATGTCGGCGGATTCCGCCGGTGCGAGGTACGCCGTGACAATGTCGTCCGAATGCGTTGTCACACCCATTTCGAGCATGCGCGCCACACCCCCCCCCCCGAGCGGTCTCGATCAAGCGAGCCGACCATTCATGTCGGCCGTTCAGCTTTCTTGTAGGACAACTCTAGGTGGATCGAAATCGGGCAACAACCCCTGCGGTCGGACGCTGACCCCTAGCGCATTACCGACGATCGAACTCCTTTTCGAAGTCGATGACGTCCGGAACGCCGCCGCATTCGTCGGCGACCTCGTCGGGGCGACTGCGCCGCCGCCGTCGCGGCTCCGCGGCGGCCGGCGGCCGCTGCCCGGTGGTCGGCACGAACACCCCGGTCCACGACGGCGACCGCGCCGAGCGTGAACCGGAGGTGGAGGTTCCGTGGTCGACCATCCTGCCGGGGCGTGCCGGGCGGGGCCGCCGCCGATGAGCCGGACGAAGCCGCACGCCGCGAGGGCGACCGGCATGACCGCCCGGGTGGGCGGGTGGCGTTGATCCCGGCCACCACGCCGGAGGCGAGCTCCCCCGGCGATGACCACCCGGCGGTGCGCGGTGAAGATCCCGGCCGGCGGCAGGAGCGCGGCGAACGCGGTGACCGGCCCGCACCTGCGAGGGCGCGGTGCCGAAGCGGCGCTGCAGCCGCGGCGCGCGGGCGCGGGTCCCGGCCGGCCCGGAGACCGGCGCTCATAAATATGTCGGGAACGGCTTAACGAACCCTTAGTTGGGCACAGGGGCCTATTTACTCCCGCGAATCAACCGTGAAACAATCGCTCCCGGATGGGCCCCGCGTCGGTTGAACATCGCTGTTGCAACGAATTCGGCATCGATCTTGGCGGCCCCCGGCGCCTCTGCTAACGTCCCGGCAGATATCGGAGTCCCGGCCTGGAGGCAATAGCGCAATGGGCAAATTCCTCCTGCGTAGGGTGGGTTACCTCGTAGTACTCGCGTTGGTCGCGACCGTGGTCGCGTACCTTCTCGCTGCGACGCAGCTCCATCCGCGGAGCAGGTATGAGGGGCGTAATCCCGCCCCGGCGGCGGCGGTCGTCGACCAGCGGCTCAACGAGCTCAACATGAACGACAAGACGCCGCTCGTCGAACGATTCACCACCTGGGCGAAGGGGGTCGCGCACGGCGATCTCGGCAAGACGGTCGACGGCGAGTCGGTGAACACCGAGATGAGCCGGCGGATGTGGGTTAGTCTGCGGCTGATGCTGATCGGCTCGATCCTGGGCACGCTGCTCGGCGTGGTCGCCGGCGCGTACGGTGCGATCAAGCAACATAAGTGGTCTGATCAGACATTAACCGGCATATCCTTTGTCCTACTATCGGTCCCCACCGTGGTGCTCGCCGTCCTGATGAAGAACGGCGGCATCTGGTTCAACCAGGCGTCGGGCCACGAGTCGAACCCGCTCGTGTTCACCGTCGGTGAGATCACGCCGGGCCTGGACACCTGGTCCTGGGCCGGTCTGAGTGACCGTTTCGGGCACCTGGTCCTGCCGACGATCGTGCTCGCGATCGGCGTCAACGGCTTCGCCTTCTACAGTCGGTACCAGCGCAACTCGATGCTCGACGTGCTCGGCAGCGACTTCCTGCGGACCGCACAGGCCAAGGGGCTGCGGCGCTGGTCCGCGCTGACCCGGCACGGCCTGCGCACCGCCCTGATCCCGATGGCGACCTTCTTCTCCTACCAGTTCGCGCTGCTCTTCGTCGGTGCCACCTTCACCGAGAAGATCTTCGGCTGGCACGGCATGGGGGAGTACTTCGTCGACTCCATCACCAAGAACGACATCAACTCGACGGCCGGGGTGACCCTCTTCGTCGCCGTGCTGGTTCTGATCGCCGGCCTGCTCTCCGACGTCGTCTACGCGATGCTGGACCCGCGGGTCCGGGCGAGCTGAGGGGGACCGAGATGACTACCGACACCGAATCCGTGGTGGTCGGCGCTCCGCCGGCGCCCCGCTCCGTCTCCCGTAACCGCCTGGTGCTGCGGCGCTTCCTGCGCCAGCGGCTGGCCGTCGTCGGGCTGATCGTGGTCGTGCTGATGGTGCTGATCGCCTACCTCGGCCCGCTATTCTACAAGTGGAAGTACGACCAGCTGGACTTCGAGGCCTTCCAGTCGCCGCCCACCCCGGAGCACTGGTTCGGCACCTACCAGACCGGCGGCGACGTCTTCTCCCGCACCCTGCGCGGCCTGCAGAAGTCGCTGGTCATCGGTCTGCTCGGGGCGGGCGCCTCGACCGCTCTGGCCGCCGTGGCCGGCGCCTTCGCCGGGTACTTCCGGGGCAGCACCGACATGGTGATCCGGGTGATCATCGACCTGATGCTGGTGCTGCCCAGCTTCCTGATCATCGCGATCTTCTCGACCGCGCTGCGGGACGGGAGCTGGCTGCTGTTCATCGTGCTGCTGGCCGGCTTCCAGTGGATGATCACCGCCCGGGTGGTCCGCGGCATCACCCAGTCGCTGCGCGAGCGTGAGTTCGTCCAGGCGGCCCGCTTCATGGGCGTACCCGGCTGGAAGATCATCCTGCGGCACATCCTGCCGAACATGGCGTCGCTGCTGATCATCGACGCGACCGTCGGCGTCAGCAGCATCATCCTGGCCGAGGTCGGGCTCTCCTTCTTCGGCTTCGGCGTGCAGCCGCCGGACGTCTCGCTCGGCACCCTGATCGCCGACGGCTCCGGCGCGGCGCTGACCAACTGGTGGCAGTTCTACTTCGTCGCGGGCGTGCTGGTGCTGCTCGTCCTCGCCGTCAACCTGGTGGGCGACGGCCTGCGCGACGCGCTGGACCCGAACTCCGAGATCGAAGGTGCGAAGTGACCGACGCGATCGTGACCCGGTATCCCTCCCCCGCCGGGGGCAGTGGAGCCGGTGCCGTCGAGCCGCTGCTGCGGGTCGACGACCTGTCGGTGACCTTCCGCAGCCCGGCGGGCCCGGTCACCGCGGTCCGGGGGATCAGCTACGACGTGCGACCCGGTGAGGTGCTCGGCATCGTCGGCGAGTCCGGGTCCGGCAAGTCGGTGTCGTCGCTGGCCGTCATGGGCCTGCTGCCGGACACCGCGACGATCACCGGCTCGGCCACCTTCGAGGGCCAGCAGCTGCTCGGCCTCGGTGACAAGCAGCTCTCCCGGGTTCGCGGCCGGCGGCTCTCGATGGTGTTCCAGGACCCGCTCTCCGCGTTGACCCCGGTCTACACGGTCGGTGACCAGATCGCCGAGACGATCCGGATCCACCAGGACATCAAGCGCGAGGCGGCCGCCGAGCGGGCGATCGAGCTGCTCGACCTGGTCGGCATCCCGAACCCGCGGCAGCGGTCGAAGGGCTTCCCGCACGAGTTCTCCGGCGGCATGCGGCAGCGGGTCATGATCGCGATGGCGATCGCCAACGACCCGGCGCTGATCATCGCGGACGAGCCGACCACGGCGCTCGACGTGACCATCCAGGCGCAGATCCTGGAGGTGCTGCAGACCGCCCGGGAGGCGACCGGCGCGGCGATCGTCATGATCACCCACGACCTCGGCGTGGTCGCCGGGTTCGCCGACCGGATGCTGGTCATGTACGCCGGCCGGGTGGTCGAGACCGGCCAGGTGGAGACCGTCTACCAGCGGCCCCGGATGCCGTACACGATGGGCCTGCTCGGCTCGATCCCGCGGCTCGACATGGGCGAGCGGCAGCGGCTCACCCCGATCGACGGCGTCCCGCCGTCGATGGTGGACCTGCCGGCCGGCTGCCCGTTCGCGCCGCGCTGCCCCATGAAGATCCAGGTCTGCGAGGAGACCGAGCCGGAGCTGCTCGGCGTGGTGATCGACGGCGCCGGGCACCTGGCCGCCTGCCACCGCAGCCCGGAGATCGCCCGCAAGGAACTGACCAACGTCGACGTCTTCCCCACCACGGTGGTGCCGGAGGCCACCGGCCCGGCCCGGCTGCCCCGCGAGCAGCGCCCCGTGGTGCTCGAGGTCAACGAGCTGGTCAAGGAGTACCCGATCACCAAGGGTGGCGTGCTGCGCCGCAAGGTCGGCAGCCTGCAGGCGGTCGCCGGGATCAGCTTCGACATCCGCGAGGGGGAGACGCTGGGCCTGGTCGGTGAGTCCGGCTGTGGCAAGACCACCACCATCATGGAGATCCTGGAGCTGGCCAAGCCGACCTCCGGCACGATCGCGGTGCTCGGCAAGGACACCGCCGCGATGAGCCGCAAGGAGCGTTTCGCCATCCGGCGCGACCTTCAGGTGGTCTTCCAGGACCCGCTGGCCTCGCTGGACCCGCGGCTGCCGGTCAGTGACATCCTGGCCGAGCCGATGGCCACCCACGGGGTTCCGGCCGCCGAGCGGGAGAAGCGGGTCCGGGAGCTGCTGCGCCTGGTCGGGCTGCGCCCCGAGCACGCCGACCGGTACCCGGCCAAGTTCTCCGGTGGCCAGCGGCAGCGGATCGGCATCGCCCGGGCCCTGGCCCTGGAGCCCAAGGTGCTGGTGCTCGACGAGCCGGTGTCCGCGCTCGACGTCTCCATCCAGGCCGGCGTGATCAACCTGCTCGAGCAGCTGAAGGTGGAGCTGGGCCTCTCCTACCTGTTCGTGGCGCACGACCTGTCGGTGGTCCGGCACATCGCCGACCGGGTGGCGGTGATGTACCTCGGGCGGATCGTCGAGATCGGCACGGCCAACCAGGTCTTCGAGGCGCCCGAGCACCCGTACACCCAGGCGCTGCTCTCCGCGATCCCGCTGCCCGACCCGGTCAAGGAGCGCAGCCGCCGGCGGATCCTGCTCACCGGCGACCTGCCCAGCCCGGCGAACCCGCCGTCCGGCTGCCGATTCCGGACCCGGTGCCCCAAGTTCGCCAACGAGCTCGACGACGCGCAGCGGCAGCGCTGCCTCGACGAGTCCCCGGCGCTGACCGTCCGGGACACCGTGGTCCCGGACCACGAGTCCGCCTGTCACTACGCGGCTCCGGTCAAGGCGATTTAACGGCCGGTGTGGCGGAGTCCGCACCGGCTGGTGTAAATGAAAGAACCTGCGTCCTTTGTAGACGCTTAGTTGTGGAGGAATTGGTGAGGAAACCCTGGAGCGCGCGAGCGATCCTCGCGCCGGTCGTGGCGGCTACCCTGATCGGGACCGCCGCGTGCAGCGGGTCGAGCGGCACGACCACCAATCAGGCTGCCCCGCCGCCGAAGGCGAGCGAGAACCAGATCAACCCGAAGTCGCGCGACCAGGTCAAGGACGGCGGCACGCTGACCTGGGCGCTGAGCGGCTTCCCGGCGAACTTCAACTACTACGAGCTGGACGGCACCGACGTCGACGCCAGCTACGTCAACCTGGCGATGATGCCGCAGCTGTACAACTACGAGGCTGACGCCACCCCGGTCTGGAACAAGAACTACCTCGCCTCCGAGCCGGTCCTCAAGACCGACCCGAAGCAGGTCGTCACCTTCGAGCTGAACCCGAAGGCCACCTGGAACGACGGCGCCCCGATCACCTGGGAGGACCTCTACTGGCAGTGGAAGTCCACCAGCGGGGCGGACAAGGCGTACAACATCTCGGCCTCCAACGGCTACGAGAACATCGAGAGCGTCGCCAAGGGCAAGGACGACCACGAGGCGATCGTCACCTTCAAGACGAAGTACGCCGACTGGCAGTCGCTGTTCACCCCGTTCTACCCGGCGTCGACGAACAAGGACCCGAAGACCTTCAACGCGGGCTGGCAGAAGTCCCCGCTGAAGACCACCGCGGGCCCGTTCAAGTTCGACTCCGCGGACGCCACCGCGAAGACCATCACCCTGGTCCGCAACGAGAAGTGGTGGGGCGACCCGGCCAAGCTCGACAAGATCGTCTTCCGGGCGATCGAGCCGAACGCGCAGGTCGACGCGCTGGCCAACGGTGAGATCGACTTCGTCGACATCGGCTCCAACGTGGACGCCTACCAGCGCGCCCTGAAGATCAGCACCGCGGAGATCCGCAAGGCGGCCGGCCCGAACTTCCGGCACCTGACGATCAACGGCACCAGCACCGTGCTGTCCGACGTCAAGGTGCGCCAGGCGCTCGCCCAGGCGATCGACCGGACCGCCATCGCCAAGGCCCTGACCGGCCCGCTCGGCATCGATCCCAAGGCGCTCAACAACCACATCTTCATGTCGAACCAGGCCGGTTACCAGGACAACTCCGGTGACATCGGCAAGTACGACGTGGAGAAGGCCAAGGCGGGCCTGGACGCGGCCGGCTGGAAGCTCAACGGCGACACCCGCGAGAAGGACGGCAAGAAGCTCGAGATCAACTTTGTGATCCCGACCGGCGTCAAGTCCTCCGAGCAGGAGTCCCAGCTGGTGCAGAACATGCTGGCCCAGGTCGGCGCCAAGGTGAAGATCAACGCGGTGCCGGTCGACGACTTCTTCGACAAGTACGTCACCCCGGGCAACTTCGACATGACGGTCTTCGCCTGGATCGGCACCCAGTTCCCGGTCAGCTCCGCCAAGTCGATCTACGCGAACCCGACCAAGAACGCCAAGGGTGAGCTGGACATCCAGCAGAACTACGCCCGGGTCGGCTCGCCCGAGCTGGACACCACCTTCAACAACGCGACCGCCGAGCTGGACAAGACCAAGGCGGCCACGCTGGCCAACCAGGCCGACGCCCAGATCTGGCAGGAGGTTCACTCGCTGACCCTCTACCAGCGCCCGGAGCTGATCGCCACCAAGAAGGACCTGGCCAACTTCGGCGCCAAGGGCTTCGCCAGCGTCATCTACGAGAACATCGGTTTCGTCAAGTAACGACGACTCCTCACCAAAGCTCGCGCCGCGCGGAGGCTGCCTCCGCGCGGCGCGAGCCGTTTCTCCGGCCATCGGGCCCGCGCCGGCCCGGTCGCGGATCTCACGCATCGTCGCCCGCCTGCGCGCACCGGCTTTCCCCGAAGCCCGACCGGTGCCGCTGAGCGAGGTTTAGTCTGCCGTTAATCAGCAACCGCAGTACTCCGGCCTCGTGGAAAGGCCCGGACCATGAATTTCCGGCAATCGGCGGTCGTCGTTCACGGCATCCATGCGGCGTACATTCCGGTGGCTTATGCGGCGGTGACCCTGTCCGCCGTGGCGGCGGCCGTGGCGCCGCCGCGCATGCTGATGTTCGGCATGCTGGCGGTCGGGCCGGCGTTCGTCGCCGCCACCGCCCGGCCGGTGGCGGTCCTCGGTGTGGGCGGCTATGCGCTGGCCGCCGCGTTCACGGTCTCCACCTGGCAGGGCCTGCTCGGCACCGCCGACCAGGTCCTGCGACTGATGCTGATCGTGGTGATGACCGTGGTCAGCTGGTCGGTCGCCCGACACCTCGGACTGCTGCTGCGCGCCGCCACTGTCGCCGCCCAGGAGCGGCAGATGCTGGCGGCCGTCGTCGAGCAGTCCGCCGACGGGATCATCGTGACCTCGCTCGACGGGGTGGTGACCCACTGGAACGGCGGCGCCGAACAGCTCTACCGCCAGTCGGCCGACCAGGTCGTCGGGACCGGGTTCGGCCGGTTCCTGCCGGCCGACCGGCAGGCCGCCTTCGGGCGGGCGCTGGCCTCGCTGGCCGCCGGTGAGCGCGTCCACCTCGACGAGGCCCGCCGGATCCGCGCCGACGGCGCCGAGATGCTGGTCTCCGTCGCGGTGTCGCCGATCCGCGACGAGACCGGCGAGGTGGTCGCGACGGCTTCCACCGAGCGCGACATCACCGAGGTCAAGCGGCGCGAGGCGGAGGAGCGGCTGGCCCGCGAACGGTCGGCGCGGGCCGCCCGGCTGGAAAGCCTCGGACAGCTGGCCAGCGGGGTGGCGCACGACTTCAACAACCTGCTCGCCATCATCCTGAACTACGCCGACTTCCTCACCGAGGAGGTCACCGAGGACGGCAGCCGGGACCTGGCCCGGATCCGCGACGCCGCGGACCGGGCACGCGCGCTGACCGGACAGCTGCTGCTGTTCGCCAAGCAGGAGTCCGCCACGGTGGAGATCGTCGACCTGAACGAGGTGGTCAGCGCGTCCAGCGAGCTGCTCACCCGGACCATCGGGGCCAACATCAGTCTGCTCTGCCGGCCGCACCCGCAGGCCCTCCCGGTCAGCGCCAACCGGGGGCGCCTCGACCAGATCCTGCTCAACCTGGTGATCAACGCCCGGGACGCGATGCCCGACGGCGGGGTGGTGCTGATCGAGACCGGCCGGGCGCCGGGCCGCCGGGTGCGGATGACGGTCAGCGACACCGGATGCGGCATGTCACCGGAGGTCAAGGACCGGCTGTTCGAGCCGTTCTTCACGACCAAGCCGGCCGACCGCGGCACCGGCCTGGGCCTGGCCACCGTCTACGGCATCGTCGGCGACGCCGGCGGCAGCATCCAGGTGGACTCCACGCCCGGGGTCGGCACCACCTTCGAGATCCTGCTGCCGCTGGCCGGCGACACCACCGGGCAGGAGCCGGAGCCGGACGCGCACCGCCCGGTCACCGGGCACGGCGAGCGGATCCTGCTGGTCGAGGACGACGAGTTCGTTCGCGACCTGGTGGTCCGCATCCTGAACGGCAACGGGTACCAGACCGTCCCGCTCGACGAGAACGCCGCCGGGGACGCCGACGTGGCCGGCGCCGCGGTACTGCTCAGCGACATCATGCTGCGGTTCCGGTCCGGTCCGGCGATCGCCGATCAACTGCGTACCCGTCATCCCGATCTCCGGGTGGTGTTCATGTCCGGTTACAGCGATGAGGAGCTCCGCCACCGGTACGACCTCAGCGCGGCGACCGGCATCCTGCAGAAGCCGTTCACCGCCGTGGAACTGCTCGCCGCCGTCGGAACAGCGCTGACCCCCGCGGTCAGCCGGCGTGGCTAGGCCGCCGGGTGGCCGGGCGACGCGAGCACAACAAGCGGGAGACCCGCCGGTCGCTGCAGGACGCGGCGCGCCGGCTGTTCGAGGAACGCGGCTTCGACGAGGTCTGCGTCGAGGACATCGCCACCGAGGTGCCGGTGTCGCGGCGGACCTTCTTCAACTACTTCGACTCCAAGGAGGCGGCGCTGGTCGACCCGGGCCCGTCGCGGGTCGACACGCTCGCCGCTCTGCTGGCCGGCCGCCCGGCGGACGAACCGCTGCTCAACAGCCTGTGCACGGTGCACATTCAGTTTCTGATGACCGACCCGGAGGATCTCGCCGCCCGGATGCGCCTGGTGCGGGCCAACCCGGCGCTGCGGCAACGGTGGATCACCGCGATCGAGACCTTCGACGCCGAGGTCGTCCGCTGGGCCTGTACCCGTACCGGGCTGCCCCCGGAGGCGGTGTATCCGCAGTTGCTGGCCGGGATCGCCGGCACCGTGTCCCGGCTCGCCATGGAGCACTGGGACCCGGACACCGCACCCGAGCGGCTCGCCGAGGTGATCTCCTGCATCTACCGCCTGCTGGCCGCGCTGGGCAACGACGCGGACCTGCCGCCGGCCGACCGCGGCTGCGAGCACTGACCGCCGGGGGTCACGCCGGCCCGCCGCCGGCCGACCGCGGCTGCGAGCACTGACCGCCGCCGGGGGCACGCCGGCCCGCCGCCGGCCGGCCCGGGCTGCGAGCACCGACCGCCAGAGGGTCACGCCGTGCGATAGCTGGTGGCGGTCCGCTGCAGGACGCCGGCCCGCTCCGCCAGCCCGCCGGCCGTCGCCCGGGTCTGGGTGGCACTGGTCGCGGTGCCGGCGGCCACCTCGGCCACCTCGGCCACCGCCACCGCGATGTCGCTCGACCCGGTCGCGGCGTGCGCCACGCTGCGGGCCATCTCGGCGGTGGTGGCGCTCTGCTCCTCGACCGCCGCCGCGATCGTCCCCGCGTAGCTGTTGATCTGCCCGGTCACCTCGGCGATCTCGGCGACCGCGGTCAGCGCCTCGGCCGCGTCCCGCTGAATGGCGGCCACCCGCTCGGAGATGTCCTGCGTCGCCTTGGCGGTCTCCTGGGCCAGTGTCTTCACCTCGCCGGCGACCACCGCGAACCCCTTGCCGGCCTCACCGACCCGGGCCGCCTCGATGGTCGCGTTGAGAGCGAGCAGGTTGGTCTGCTGCGCGATCACGTTGATGATCGTCACGACGTCGCCGATCTCCGCCGACGAGTGGTCCAACTGGGCGAGCACGTCGTTGGTGCGCTCCGCCGAGCTGCTGGCGCGCGCCGACACCCGGGCCGCCTCGGTGGCGTTGCTGGCGATCTCGGCGATCGAGGCGCCCATCTGCTCGGCGCCCGCGGCGACGGTCTGCACGTGCCGGCACACCTCCTCGGCCGCCGCGGAGACCGCGACCGCCCGGCCGGAGGTCTGCTCCGCCGCCGTGGACAGGTGCGTCGACACCTCGGAGAGCTGCTGCGACGCCGACCCGAAGAAGGCCGCGTCGTCCGCCATCCCGCCGACCATGGCCGCGGTGGCGGCGGTCGTCCGGTCCAGGGTCGCGGCCAGCCCGGCCACCTCGTCGCTGCCGGTCACCTCGGTGCGGGCGGTCAGGTCGCCGTCCGCGATGCTGCGCAGCACCGTCACGCACCGGTTCAACCTCCGCGAGATCGACCCGGCGACCGCCGCCCCGAACAGCCCGGCCGCGATCATCCCCACCACGCTGACCACACCGAGGACGATCACCGCCTGCCGGAAGGTGTCCGCGGTGGCGGCGTTCTTCTCCCGGGCCACCCCGGTCTCGATGCCGACGAGTTTCTGCAGACTGCCGTCCAGCCGGTCCGAGGTGGTTGTCATCGCGCCGCCCCAGACGCTGACGAATGCGGCCCGGTCATGATTGCGGATGGCCGGCAACAATTGTTCGTCGCGCAATTTCCGATAAGTGTGTACGGCATCGCTCACGGTCGCCACCTCCGCCTCCCGGCCGCGCATGTCGGAGGAGGTGTAAGCCGCGAAGGCGGCGTCGAAAGCGGCATCCTCGCCCTGGTCGAAGCGGGCCTCGACGCCCTGCCGCGACAAGGCCGCGGTGAGCAGGCTGGCCTTGGTGACGCCGGCCGACCGCTGCATCGCCGTCACCTGGGTGATCGGCACCAGATTCTGCTGGTAGACGTAGTCGGCGGCGGCCCGCATCTGCCGCATGCCGGAGATCGCGGCGATGCCGACGGCCACCGTCGCGATCGCCATCGTGGCGACCGCCAGCAGTATCTTGGTGCCGACCCGGCGGTTGGTGACTGCCAGCATCAATGGCGCAAAAATTCGTGCGATCATCATTCGCGTCCCCCTCGGATGATTCCGCTTCCGGCCATACCATCGGTGCCGGGCCGCGCGGAATGACCCTCAGCGCCGAAGTTGCACGCAGGGAAAAGCCATTCGGAAATTGCACTGAGGGAAAGTCGCGTCAGCGCAGGGTGGCGAGGGCGGCGATCGAGCAGATCACCATGGTGGCGCCCATCGTGATGGCGGTCGCCGGACCGGCCAGCGTCATCGCCGAGGCGGCGAGGCTGCCCACCAGGAACTGCAGCAGGCCCTGCAGGGACGAGGCGGCCCCGGCGGCCGACCCGTGCCCGGCCAGGGCCAGCGAGGTGGCGTTGGCCAGCACGATGCCGAGCATGGCGACCGGCAGGAACAGGAAGGCCAGCAGCAGGGGCAGCGGCAGGCCGGCGACGGCGCAGACCAGCACCCCGGCCGAGCCGAGGACGGCGATCGAGAGGCTGACCCGCAGCAGGGTGTGCTCGCCGGTGACCCGGCCGACGAGCATGCCGCCGATCTGCCCGAACACCACGATGCCGAGCCCGTTGAGGCCGAAGACCAGGCTGAACTGCTGCGCGCTGAGTCCGTAGGCGTCCTGCAGGACGAACGACGAGCCGGAGATGTAGGCGAAGACGGCCGCGAACATCAGCGCCGCGGCGACGACGTAGCGCAGATAGTGCCGGTCGGTGCCGAGCGTGCGGAACGCCCGCAGGGTCGCCCGCGGGTGTGCCGGCGCACGCCGTTCCCGGGGCAGCGATTCGGGCAGGGCGAGGGCGACAGTGACCAGGAGGATGGCGCCGACCGCGGCCAGCACCAGGAACACCGCCCGCCAGGTGGTGAAGGTGAGCAGCTGGCCGCCGATGACCGGCGCGACGATCGGTGCGACCCCGTTGACCACCATCAGGGTGGCGAAGAAGCGGGTCATGGCGGTGCCCTGGTAGAGGTCGCGGACGATGGCCCGGGCCAGGACGGTGCCGGCCGCCGCGCCCAGCGACTGCAGCACGCGGCCGCCGATCAGATAGCCGGCGGTGGGGGAGAGCGCGCACCACAGCGATCCGGTCACGTAGAGCGCCATCCCGGCGAGCAGCGGCCGCCGCCGGCCCCAGGCGTCCGAGAGCGGGCCGACGATCACCTGGCCGACGGCGAGCCCGACGACGAACACCGTCAGGGTGAGCTGTACCAGGGTCGCGCCGGCGTCCAACTCGTCGGCCATCCCGGGCATGGCCGGCAGGTACATGTCGATGGTGAGCGCGCCGAACGCGCTCAACGCGCCCAGGATCAGGGCCAGCCGCGCCCGGTGCCGCGCCGTGGGCGGAGCTTGAGTTATGGACACATAATTATGATGCCATAATCAGGGGGTGACCCGTGACGATGCCGGCGCCGCGCTCGCGGATCTCGCCGACCTGATCCTCAACGTCGGCCGCCTGGTGCGCGCCCGCACGCCGGACGAGAGTCCGGACGTGGTGCCGTTGACCGAGACCGAGCGGCAGGTGATGCGCATCGTCGACCTCCACCCGGGCGCCGCGCCCAGCGAGATCGCCCGGCGCACCCGGCTGCAGCGCACCAACGTCAGCACGGCGCTGCGCGGGCTGGAGGGCAAGGGCATGGTGTCGCGTGCCGCGACCGCCGGCCGCGGCGTCGCCGTGCACCCGACCGAGCTGGCCGCGGCCAACCTGCGGGTGCTGCGCGCGGCCTGGGCGCGCGAGCTCGCCGGCGACCTGGGCGACGACCTGGACGCGGTCCGCCGGTGCACCGACCTCCTCGGCCGGTTGGAGCGGCAGCTCACCGCCGACGAGCCCTGACCCGCGGACGGCTCAGCTGAGGCGGGCCTCGTCCGCCTTGTCGTACGGGCGGATGTCGGCCAACCGGCCCGCGCGCAGCTTCGTCGGCCAGGCCGGCTCGGAGAGCAGGGCGCGTCCCAGGCCGACCAGGTCGAACTCGCCGCGTTCGAAGAGCTCGAGCAGCGGCGCGACGCTGAGGGTCGGTGCCGGCTCCTCGGTCTCGCCGCGGAAGGCCTGCGCGACCCCGACCGAGCCGATCGCCACGACCGGCAGCCCGGTCACCTTCCTGGTCCAGCCGGCGAGGGTCAGCGGCGAACCCTCGAAGGCCGCCGTCCAGTACCGCCGGGTGGAGACGTGCAGGCCGGTGACCCCGGCGTCGACCAGCGGGGCGAGGATCTGCTCCAGCTCACCGGGGGTGTCGGCGATCCGCGCGTCGAAATGGGTGCCCTTCCACTGCGAGAACCGGAACAGCACCGGGAAGTCCGGTCCGACGGTCGCCCGGACCGCGGCGACCACCTCGGCGCCGAGCCGGGCCCGGTTGGCGAGGCTGCCGCCGTACCCGTCGCCGCGGTGGTTGGTGCCCGCCCAGAGGAACTGGTCCAGCAGGTAGCCGTGTGCTCCGTGCAGCTCCACGCCGTCGAAGCCGGCGAGCTGCGCGTCGCGGGCCGCGGTGGCGAACGCGGCCACCACCGCGTCCAGGTCGGCGGTGGTCGCGGGTTCGCCGACCACGGTGCCGTCGGCGCGCCGGCCGGACGGGCTCAGCACCGGCGCCTCGGGGTGCGGCGGGGCGCCCGCGGCCCGGGTGGCGCCGAGGTGCCACAGCTGCGGCACGATCCGGCCGCCGGCCGCGTGGACGGCCTCGGCGACGGCCCGCCAGCCGGCCAGCGCGTCCGCGCCGTAGAAGCGCGGGACCCGGTCGCTGGACCCGGCCGACGGGTGGTCGACGTAGGTGCCCTCGGTGACGATCAGCCCGACGTGCGGGGCGCGCCGCGCGTAGTAGGCCGCGACATCCTCGCCGGGAACCCCACCGGGCGAGAACTGCCGCGTCATCGGCGCCATCACGAAGCGGTTGGCAAGATCGATATCGCCGATCTTGTACGGGGTGAACAGCGGCGCCGGATCGATAGTCACACCACGCTCAAGACCGGTGGGCGCGCCCTTAATCCGGATGTGGCGCATGTCATATTTCTCCTATCGGCTTCAGGGGCGCAGATACCGGAGGACGGCGAGGACCCGGCGATGGTCGGAGTCGGTGTGCGGAAGATCCAGCTTGGTGAAGATGCTGCCGATGTACTTCTCCACCGCGCTGTGACTGACCCTCAGCTCGCCGGCGATGCCGTTGTTGGACCGGCCCTCGGCCATCAGCCGCAGCACCTCCGACTCCCGGGGGGTGAGCCGCTGCAGCGGGTCGGCCCGATGCCGCACGAGCAGCTGGGCGACCACCTCGGGGTCGAGCGCGGTACCGCCGGCGGCGACCCGGCGCATGGCGGCCAGGAAGTCCGGCACGTGTGCCACCCGGTCCTTCAGCAGATAGCCGACGCCGCTGGTCCGGACGGACAGCAGGTCGGTGGCGTACCGCTCCTCGACGAACTGGGACAGCACGACGACGGCGACGGCCGGGAACTCGTGATGGATGACCAGGGCGGCCCGGATGCCCTCGTCGGTGTGCGACGGTGGCATCCGGACGTCGACGAGCGCCACATCGGGCCGGTGCGCCGCTACCGCGCGCAGCAGCTCGACGGCGTCGGCGACCGCCTCGACGACGTCGAAACCGCCGTCGGTGAGCAGTTTGGTCAGACCGGCCCGCAGCAGCACCGAATCCTCGGCGATCACGATCCGCACGGCAACTCCACGGTGATCGTGGTCGGCCCGCCGGTCGGGCTGTGCAGCGCGAACGTCCCGTCGACGGCGGCCGCACGCCGGGCCAGTCCGACCAGCCCGGTGCCGTCGCCGCCGGTGGTCGCGCCACCCCGGCCGTCGTCGGTGACGACGACCCGGAGCCGGTCGGCGGCGCGTTCGACGATCACCTCGGCGCGGGTGGCGCCGGCATGCTTGCTGACGTTGGTGAGCGCCTCGGAGACGACGAAGTAGGCGATCGCCTCGACCACCGGCGAGCACCGCGCCGGCACGTCGACGAGCAGCCGGACCGGCAGCGGGGCCCGGGCGGCGATGCCGGACAGCGCCGCGTCCAGCCCGCGGTCGTCGAGCACGGCGGGATGCAGCCCCCGGACGAACTCGCGCATCTCGGCGAGCGCCTGAACGGCCTCGTCGTGGGCGTCCTCGATCGCCCGCATCGCCGGCCCGGATGTCCCGGCGAGGGTGGCGCGGGCCATGCCCAGGTTCATCGCGAGCGACACCAGCCGCTGCTGGGCGCCGTCGTGCAGGTCGCGTTCGATCCTGCGGCGTTCGGCGTCGGTCGCGGCGACGACGTCGGCCCGGCTCCGGGCCAGCGACTCCACCCGCATCGACAGCTCCGCCCGGCGGCCGGGGCCGAGCAGGGCGCGCGCCAGGGCCGTGTCGGCGCGGGCCACCCGGGCGGCCGTCCAGGGCGCCACGAGCACCAGAACGGCGAACGCCACGCCGGTGAAGCAGGCCAGCAGGTGATAGGCGATCTGCCGCCCGCGGGCCGGCCGGACCGGCGGTGGGATGTCGGCGCCGAGCAGCACCCGGAACCGCCGCCGCTGCACCCCGGTCAGGCGCCGCGCGGCCTCCGGTGCCAGCCCCGGCGCGACCACGGCGAGCAGCACGAACCCGGCAGTCGCCGGCCAGTCGCCGGGGCCGGCGTACAGCAGGCTCCAGCCCGCGCAGTAGACGGCGCCAACCGGCAGCACGCCGGTCAGCGCGAGACCGAGCACGCCGAGCGGCAGGCCCGCGAGCGTGTGGACGGCAACCCGCCAGGTGCGGGCCGCGCCGGCCGGCACCGTCCGGGAGTTCCCCACTTCCGCCGCTGTCATGTGATCAAGGTAAACACCGTCCGGCGCCGTGGCGACGGGGCCACCCGCCGGTCCGGGGTGCGGAAAACCCCACCCCGGACCGGCTGCCCGCCCCACCGACACCGCGTCGCGCGTCCGGCAGCGTGATGGGCATGCTGGAACCGACCACAAACACCGACACCACGGCTGCGGTACGCCCCCTGCGCCGCCGTACGCTGCTCACCGCGACCCTCGCCGCCGGGATCGGCCTGGCCGCGGGCATCGGACCCGCTGTCCCCGCCGCTGCCCGTCGTCGGTCGACCGGGGGATACGTCCTGCCCGCGCCGACCGGCACCGCCGGGGTCGGCACCGTCGCCCTGCACCTGCGGGACACGAGCCGCATCGATCCGTGGGTGCCCGGTCGCCGGGCCCGGGAGATCATGATCCAGATCTGGTATCCGGCCCGGGACCTTCGCGGCCATCTGCCGGAGCCGTGGCTGTCACCCGGCGCGGTGCCGCATTTCGCCGAGACCTTCGGCCTGCCCGCCGACCGGATCCTGAGCACCCGCACGCACGGCCGGACCGGGGCGCCGGTCCTGCGCAGGACCGGCGGTCACCCGGTGCTGCTGTATTCACCGGGCCTGGGCGGCGATCGCGGCACCGGTACCGTCCTCGTCGAGGAACTGGCCGCCCACGGCTACCTCGTCGTGACCATCGATCACACCCACGACGCCTCCGAGGTCGAGTTCCCCGGCGGGCGGGTCGAGGTCGCCGCCCTCCCGCCGGATCTCACCGACGAGGTCGTCGTCCAGGCCGCCGCCGTCCGTGCCGCCGACACCCGGTTCGTCCTCGACCAGCTGGCCGTCCTCGACGCCGGTGGCCATCCGGACGTCGGCCGCCGGCGGCTGCCGGACGGTCTGCGCGGCGCGTTCGACCTGCACCGCATCGGCATGTTCGGTCATTCCCTCGGTGGCAGCACCGCCGCCGCCGTGATGCACGACGATCGCCGCGTCAAGGCCGGCGTCAACCTGGACGGCACCTTCGTCGGCCCCGCCGCGGCCGGTGGTTCGACCCGGCCGTTCCTGCTGGTCAGCAGCGACCACGGGCCCGGCGCCGAGGATCCCACCTGGAACACGTTCTGGGCCGCCCACCGCGGCTGGAAGCGCCAGCTGAGACTGCGCGACTCGGTCCACGGGTCGTTCAACGACGGCATCGCCCTCTATCCCCAGGCCGGCACCGAGATCGGGCTCACCCCGCAACAGCTGGCGGACCTGGTCGGAACCCTCGACCCGGCACGATCCATCGGGATCCAGCGCACCTATCTGCGCGCCTTCTTCGACCGGCACCTGCGAGGCCGGGACGGTCGCCTGCTCGCCGCCCCGGACCCGCGTTACCCGGAGATCGACTTCGTCCGGTGACGAGGCTTCGCCCACGGCGGGGTGGCCGGTCCCGGGGAGAGCGGCTGCGGTTCGTTCTTCAGCGCGTCCGCGCGGTGCCGATAACCATGCGGCATGGACAGCCGCCCCGGCGGCTCGCGTGAGGGGTTCCAGGAAGGGACGGGCACGGCATGAGTGCGACGTGGGAGCAGCCGCAGCCGTGGGCTGTGCCACTGGTCAGTGTGTCGCTCGGTGGCGGTGAGGCGCGCACCTGCCGGGTCACCCGGCAGGCCGACGGCACCCTGCGCCTCGGGCTGACCGGGTTCGCGATGATCGGGGTCGACGCCACGCTGCTGTGGACCCAGAACAATCGCGGGTGCAGCATCGACGGCACGGTGATCGCCCCGCCGGCCGGCAGCCTCCCCGGCGTCTACCTGCGGGTGGACGGGGCGGCCGGCGGCATCCAGCGGCGGCGGACCGAGCGGGTGCGGGTGCAGTTGCCGGCCGCGGTGCGGCTGCCGTCCGGACAGCTGTTCCCCGGCCGGACGGTCGACCTGTCGGCCGGTGGGGCGCACGTGACCGTCGACCTGGAGGAGATCGGCGACGAGGCGCTGATCCGGCTCGTCGAGGACCTGGAACGCGACGTCCTGATCGAGGTGCAGATCGGGCTGCCGGACGGGCTGGCCGGGATCACCTGTCAGGTCCGGGCCGGCGGCGACGAGCCGGGCGACGTGCGCCTGCTGTTCATCAACATGAACCCCGAGGTCCGGGCCCGGGTCGTCCGGTTCGTCGAGGCGAGTGCCCCGGCCGTGGTCGGCTGATCAGGCCCGGGCGGCGGCCGGTGCGGCGCCGCGCCGGCCCAGGGCGGGCGCGATCAGCCGTACCGTGTCGTGCAGGATCTGCTCGTAGTCGTCGCGGCGGAATTCGTACGGCAGCTCCAGCCTCAGCTCCGACACCCGGGCCAGCACCGGGTCGGCGGTGAGCCGCTCGACGATCTCCGCGGCCGGGCCGACGAGGTCGGGGGCGAACAGGATCCGCCGCTCGCCCTGTGGCTTGCCGGTGCGGTCGTGACGGCTCGCCGCGTACGCCCGATAGCGGTCCCGGGTGGTCCGATCGGCACTGTCGGTCGGCACGATCACCCGGCCGATCGCGACCCGGGCCGGCCGGCCCGGCGCGACGTCGCGCCGGTATTCCTCGAGCAGGTGCAGCTGGGCGGCGGCGAAGTCGTCGTGCCGCTCGCCGGCGACGATGTTGCCGCTGAGCAGGTTCAGGCCGTTCGCCCCGGCCCAGCGGGCCGACGTGGCGCTGCCCACGCCGTACCAGAGCCGGTCGATCAGACCCGGATTGTGCGGCTGCAGCCGGGGCCGCTGGGTGTTGCCCGGCGACCGGATCACCGTATCCGGCCCGCCCAGGTAGTCCCCGCGCAGGTTGTCGGCCAGGCGGGCGATCCGCCCGTGCGACAGGTCGAAGCCGCGCCAGTCGCCGTCGAACACCAGCGGCCCGAGGAGCTCGGCGTGCGGCGGGGTCCCGGCGCTGAACCCGGCCTGCAGGCGCCCGCGGGACAGCACGTCGGCCAGCGACAGGTCCTCGGCGAGGCGGAACGGGCTCTCGTAGCCGATCGGGATGACCGCGGTGCCCAGCTCCACCCGTTCTCTCCCATGGGTGAAACGTCGAAAGTGGCGGACCGCCGAGATTTCCGGATCGGTCCCGCCGGACTTCTTGGGTCGGCCCCGGATCCACCGATAAACCTGGTGTTCCGCCGTGGCATGTCCTCACCTGGGAGTCCGCTCTTGTCCAGTCGTCAGTTCGTCACCTTCGAGGTCGCCGGTCAGTTCTTCGGCGTGGATGTGGACGCCGTCCAGGAGGTGTTGTCCTACAGCGAGTACACCCCGGTGCCGATGGCCCCCACCGCGGTCGGCGGCCTGTTCAACCTGCGCGGTCAGGTGATCGCCGCGGTGGACCTGCGGGTGCAGTTCGGTCTGCCCCGCCGGGACATGACCGGCCTGGTGATGAACGTGATCGTCCGGCACGACGGCGAGCCGGTGAGCCTGCTGGTGGACCGCATCGGCCAGGTCGCGTACCTGGACGCGCAGATGTTCGAGGAGCCGCCGGCGACGCTGACCGGCCCGTCCCGGGCGCTGGTCACCGGTGCGTACAAGACCGAGGGCCGGTTGCTGCTGGTGCTCGACGTCGCCGAGTGCGTGAACACCTCGCGCGTCACCGCCTGAGGCGGCACCGGCCGGGATCTCCGGTCAGGGACGTTCGAGCAGCACGAATCCACTGTCCCTGGTGACCGTCCGGTAGCCGGCGGCCACCAGGGCCTCGACCCTGGCGAGCCGGATGTCGCGCGGCAGCGGCCAGTCGTCGACTTCCAGGTCGACCACGACGTACCGGGGAGCCGGGCCCGGATAGTCCAGCCCGAACAGCGTGACCGTCGTCCGTCCGGTCAGCTGCGGAACGAGCCGGTTGGCGGCGGACACCGTCGCGCCGTCCGGAATCAGGTCGAGGACCCGATGCGCGGCGGTACCGCGGGGGTCGCCCCGCCAGATCGGCGCCGAGGCCAACTGCGCCAGCGGGTACCGCGGCAGCAGGAACCCGGTGACGGCGAGGCTGGCCACCAGCACGAGCCGGGTCGCCGCGGCACCGGTGCGGTCCGCGGCGGGCCGCCGGCGCGTCAGGCCGTCGACGAACGCCAGCATCATGACCGGCATCAGGACGGCGCTGTAGTGGAAGCCGGTGCCCCAGTAGTTCGGGTTGCCGGAGGCGAAGCGCCAGAGCAGCGTCGGTACCGCGACCCAGGCCAGCGGTGATCGCAGCGCGACGCCGGCGGTCGGCGCCAGCAGGGCGAGCACGGTCAGCAGCTTGACCGCCGTCACCGGATGCTGCAGCCCGGAACCCACCGCCGCCGAATAGGCGTAGGCGTCGTCCGGGTTCAGGGCGGGGACGACGACCCCCATCGCCAGTGCGGTGCCGAGCAGCCCGGCGGCGGCGAGCCCGCCACCCAGGCGGCGGGCCCCGAAGGCCGCGACGAGCAGGCCGATCACCGCCACGGTCAGGCCCAGGTCCTCCTTGACCAGCAGCAGGGGCAGCGCCCACCCGCTGGCCGCCCGCAGCCGCCGGTCGGCGAGCGCGGCGAGGCTGAACGACAGCAGCGGCACCGCGAAGCACACCTCGTGGAAGTCGAAGCCGACGGCCGACGCGATCCCCCAGGACAGTCCGTAGCCCGCCCCGGCGGTCACCGCCGCGAACGCGCCGAGCCGCCGGTGGGCGAGCGACATGATCGGTACGACGGCGACCGCCAGCAGCAGCGCCTGGGCCACGAGCAGCGTCACCGGTGTGGGAAAGATCCGGTAGAGCGGTGCCAGCAGGGCCAGCACGGGCGAGAAATGGTCACCGAGCTGCGGGAAACCGGGCCCCTTGAGCGGTACGAGGCCGGGCCGGCCCGCGGCGTACGAACGCACCGCCTGTTCGAAGATGCCCAGGTCGAACCCGGTGGTCCGGAGCCGCCGATGGTTGAGCAGGGACAGCAGCAGGTAGATCACGGCGAGTCCGCCGGCGCCGGACCAGGCGAGCACGGCGCCGGAGCGGCGCACCGGGGTGGCGCGCGCCGCCGGGACCACGTCGTGGCTGAGGACGATCATGGAGCGGGATCCTGCGCCGGGCGGGTTGACCCGTACCTGACCCGACCTGACCGAGCGATCAGGAAACGATCCGGCGCCATGCGATGCTGCACGCCATGCGCCTGCTGGTGATCGAGGACGAGCCCGAGTTGGCGACCATCCTGCAACGGGGACTGACGGCCGAGGGGTACACCGTCGACGTCGCCGGTGACGGACGGGTCGCGCTGGACCTGGCCCGCTTCGAGGACTACGCGGGCATCGTGCTCGACCTGATGCTGCCGGGACTCAACGGCTACCGTGTCTGCGCGACGTTGCGCCGTGAGGGGATCCGCACCCCGATCCTGGTGCTGACCGCGAAGGACGGCGACTACGACCAGATCGAGGCGCTCGACACCGGTGCCGACGACTTCCTGAGCAAACCGTTCTCCTACCCGGTGCTGGTCGCCCGGCTGCGGGCGCTGGTGCGCCGCGGTCCGGCCGCCGTCCCGGTCCGGCTCACCGTCGGCGACCTCGTCCTGGAACGGGCCGCGCGGACCTGCCGGCGCGGTACGGTGCCGATCACCTTGACCCCCCGCGAGTTCGCGATCCTGGACCTCCTCGCGCACCGTGCGGGCGAGCCGGTCACCAAACTGGAGATCCTGCGTCAGGTCTGGCCCGAGGACGTGGACGACCCGAACCTGGTCGAGGTGCGCGTCGGCCGGCTCCGCCGCAAGATCGATCTGCCCTTCGGGCGCAGCAGCCTGCGTACGGTGCGGGGCACCGGTTACCGCCTCGTCGACGACCGGGCGGCGGCATGACCGGCCTGCGGTCGGTGCGCGCCCGATCCGCGCTGGCGGCCGCCGCGGCGGCCGCCGTGATACTGACCGGCGGGGGACTGTGGGCCCGGCACTTCGTCGGTCAGCAGCAGCTGGAAGCGGGCCGGCGCAGCGCCGTCCAGCAGGTCAACGCCATGGGTCTGGCGGCGACCACGATCGGGACGGGCGGCGCGGAGGAACTGCGGCCCGCCTTCTACCCCGACGTCACCTTCGAGGTGGTCGACACCACCGGGGCGGTGCTCTCGGCCAGCCCCGACCTGGCCCCGTACGAGAGCGACGGGCGGGCCGTCATGCCGGCGGCGGACCCGCTGCCCGGCGACATTTCGATGGACACGCCGGAGGTCTCCGCCACGGTCCGGCTGGCCGACCCACCCGGAGACCACGCCCTCGACGGCCGGACCGTCACCGGCGTCCGGATCCAGGGCGCCCCCGTCAGCATGACCGACCACCCGGAACTCGGGCCGACGTTCGCCGTCTACGTGTTCGTCACCCCGCTCGCCGCGGAGCGGGCGGTGGCCACCGTCGACCGGATCCTCGTCGGCGCCGTCCCGCTGGCCGTCCTGGTGGTGGCCCTGGTCGCGTGGTTCGCCACCCGCCGGGCGTTACGCCCCGTGGAGGCCATCCGGGCCCGGACGGCGGAGGTCACCGCCAGCCGGCTCGCCGACCGCGTCGAGGTGCCGGCCACCGGCGACGAGATCGCGGCGCTGGCCACCACCATCAACGCCATGCTGGACCGGCTGCAGCGCGCCGATCGGGCCCAGCGCCGGATGGTCTCCGACGCCGCCCACGAGCTGCGCAGCCCGCTGGCGATCCTGCGGGCCGGCCTGGAGGTGGCCCAGGCGTATCCGGACCGCACGGACTGGCCGGCCACCGCGGCGACCGCGGTGGCCCAGGCCCAGCGGCTCACCGGCCTGGCCGACGACCTGCTCCTGCTGGCCCGCCTGGACGCGGGCACCGCGCCACCGCAACCGGAGGTCGACGCCGACGTCGTCGCCGTGCTGTCCCGGATGGCGGTCGAGACCATCACCCGCGACGGCGTCACGGTGACCGGCCCCGCCGGCCCGCCCGTGCCGGTACGGCTCGCCCGGGTCCCGTTCGAACGCATCGTCCGCAACCTGCTCGACAACGCCGTCCGGCATGCCGGACGGCGCGTCGAGATCCGGATCACCGCCGACCCGGCCGCCGCCGGGCGGACCCGGCTGCGGGTCGAGGTCGCCGACGACGGCCCGGGCATCCACCCGGGCGACCGTGACCGGATCTTCGACCGCTTCACCCGGGTGGACGCCGCGCGGGACCGGCACGCCGGCGGCGCCGGCCTCGGACTGTCGCTCGCGCGGGAGCTGGCCACCCAGCTCGGGGGAATCCTGCGGGTGGCGGACCGGCCCGTCCCCGGGGCGACGTTCGAGCTGACCCTGACCGTCACCGCCGCCTGAATGGTCCGGTCCCGGTCCTCAGGGGGCGGAGTGCCGGACGGCCGCCACCCCGGGCAGGCCGCCCACCTCGGCCACCAGGCCGTCGAACCCGCCGGGGCTGCTCAGCTCCACCAGCCAGAACCCGGGCAGCGTCGCCCGCGAGGCACCGGTGATCCGGCCGCCGCCGCAGTACGCGTCGCGGTAGTCCTGGTCGGTCACGTCGCCGGACCAGGCCGTGGACCGCACGGACGGCACATGCCAGATCGCGGCCTGGGCGATGTTGCGCTGTTCGGCGGAGGCGTCGCCGGTCACGTAGACGCGGGCCGTCAGGCCGGTGGCCACCTCGGCGGCCGGCAGCGCGGCGGGCGGCCCGGACGGGGTGCATCCCGGTCGTGTCCAGCTCGGCCGGCCGTTCATGGCGACCACCATGAACAGCACCAGCGCCGCCGCCGCGAGGATCCTGTGCCGGGCCGGCAGGGCGGCCGTCACCAGCGCCAGCATGCCCAGGCCGAACACCAGCGTGGTGGGTGCCCCGGACAGCTGATCCAGGGTCGTCCACAGCGGGCGGCCCTCCAGCGGCCCGGGCTGGGTGTACCACAGGCAGATGAAGTACAGACTCGCCGCGACCACGAGCATCGCCGACCAGACGAGCAGGACGGCGCCTCTGGTCCGGGCCGGACGGCCCTCGCTGCGTCGGCTCGCCCAGCCGAACAGCAGCCAGCCGGCGCATGCCGCGAGCAGCCCGGCCGGCACCGCGAACCGGGCCGGCCACGGTGGCGTCGTGCGGGACAACTGGAAGCCGGCCGAGCCGTCCGAGTCGTACCAGGGGTGGTCCTTCACGTAGTAGGCGCTGTAGTTCAGGATCAGGTCGTCCCGGGTGGCGGTGAACCCGGCGCTCCACGACGCTTGCTCGTCGTCCTGCTCGGCGGTGACGTCGTCGCGGATCTGCCAGCCCGCACCGGCCAGCCGGTCCCGGACGCCTCTGGTGTAGGCTGGCACGTCGCGGGTCTCCGGGGTGTTGCGCACCCAGTACTCGGCGAAGCCGTAGACCTCACCGCCGTCCGCGCCGGAGGCCGGTACGAACGGCGGGGCGTCGCCGCCACCGAGCACCGGCAGCCCGGGGAAGGCGGCCGTCGTGAGCTCTCGCGCCTGCGCCCCCGAGGGCAGCGGCTTCTGCAGCATCCAGCCCAGGCGGGCGCCGGTGGCCGCGCCCAGCAGCCCGCAGACGAGCGCGACCAGCAGGGACAGCAGCACCACGCTGGTGCTCGCGGGCCGGCCGAGGCGGGCCCGCAGCCCGTAACGGGTCAGGTTCACGATGTCCACCGCGGTCGGCCGGTCGCGTCCGGGCGGCGCGCATTCCAGCAGGGTGCCGAGCATCTCGGCGCGGCGGGGGCCGGGCGGATAGCACCGGAGCAGCCGGGCATACCGGCGGGCCAGCCGCTCGCTCACGAGGTGCTCAGGCTCAGCCCGAGCCGGCGGCGCGCCGACAGCTGCGCGGTGGCCGCGGCGACCGCCGCCCGCCGCCGCTCCGTCTCGGCGTCCAGCGCGGCGGCGCCGTCGGTGGTCAGCCGGTAGTACCGTCGCGGCCGCCCGTCCACCGTCTCCTCACGGTCCGCCTCGATGAGGCCGAGCGAGGTGAGCCGGTCGAGGGCCGCGTACAGGGTCCCGGCCTGCAACGTCACCTGGCCGTCGGAGAGTCGGTTCACCTCCCGGATCACCCCGTAGCCGTGCCGCGGCTCGGGCGCCAGGGCGGTGAGAACCCAGAAGCTGGGGTCGCGCATCGGTTCCGTCATGCCGCCCAATATAAAGATGATCTTTATATGAGACAAGATCAAGGGCACCATCGATTACTCGGTACGGTCGTCAGCCGGCGGTCGTCAGCCGTTCGCGGCGGCCGGCGTGTGTCAGCCGTTCGCGGCGGCCGGCGTGCGTGAGCCGTTTGCGGCGGCCGGCGTGTGTCAGCCGTTTGCGGCGGCCGGCGTGTGTCAGCCGTTCGCGGCGGCCGGGCCGCGCAGTGCGAGAGTGGCGTGGACCTGGGCGAGCTGCGTGGTGGCGGTGAGCATCGCCAGGTCCGCGCCCGGCACGTACGGCTCCTCGGAGTGATCGTCCTCGTTGATGTTGGTGTGATAGTCGACGAGGCAGATCTGGTAGAGGCGCTCCGCCTCGTCGATGAGCTCGGCGGCGCGGGCGGCGTGTTCGTCGGCGGTCATGCCGATCATGGTGTCATCCGGGCGACCCGGCCACCCCGCCCCCTTTCCGGCCCGGGTCAGGAGCGGAGGCCGCCGCCGCTCACCGGGCCATCAGTGCCTGATCAGAAAGTACGCCAGGAGGAAGATCGCACCCGTCACCGCGAGCGGCACGAGCAGCAGCACCAGCGCCGGGCGGCGGTCGGGGGACACGGTCGGGGCCGGATCGGGCGGCGCGAGCGGCGGTGACGGCCGGGTCGCGGCGGTGGGCCACAGCTCCGCGCCGCACACCTCGCACCGTACCCGGGCCGTGGGGTTGCCGTGACCGCAGTCGGGGCATCGCGGGCCGGGGACGCGCTTCTCCGGTGGCCGCAGCCGGTCGTCACGGGCAGCGCTCCGGCCACCCGTGTCCGCCTCCTGTCCCGGGGTCCGGGGGAGGCGCAACATCCGATCGTCCGGCTCCATCACATGTCCCCGGAGAAGACGCGCGGGCCGGAAACGCGGGGACCGCGTCGCAGGCGCCGCATCACTGCTCCCGGCCGGCCACGACGAGCCGGTAGCCGACGCCGACCGGCAGCTCCTCCCGGATCGCCGCGTGCACCTGGGCCACGTCACACCTCCCGGTGCCGGACATCTCGATCCGTACGTCACCACCCGGCCGGTCCGGTTCACCGGGCAACGCCACCCCGCCCGGGTCGCCGATCGTGACGTGGGCCCCGGTCAGTGCGCTCAGCAGGCGTTCGAGCCCGTAACAGGTGCCCCGGTACCCGATCACCGATCCGACCGCGCGGATCAGCCGACGCTGGTCGTCCAGCTCGGCCGGGGTGGTGGCCGGCCGCAGCGAGACCGCGAGCCAGGACCCGAGGTACGCGAGCATCTCCGGTGAGGCCAGGTCGACGTCGAGCTCGTGTTCCAGGTCGTCGATCTGGGCCCGGACGGAGTCCGCCACCTGCTGGCAACCGGTGACGAACCCGGCCAGGAACGGGTCACGGGCCATCGTCTGCGGCAGTTGGGCGAGCAGCCAGGTCACCAGGCCACCGCCACCGTGTGCCGGTCGGAGAGGAAGAGTGCGGACGGTACGAGCGGTACCTCCTGGCCCCCGGGAGCGTCCTCGCGCTCACCCCACAGATCGGTCAGCGTGAGATTGACCGAGGTCACGGCGGCCACTCCCGGCACCGCGCCCAGGACCAGGTAGATGTCGCCGACCCCGAGCGCGCGCTCGAACGGCCAGCCGTGACCGCCCGGACCACCGGCCACCGGGTCGAGGAACCGGTAGAGCGCGTCCTCGGCGTCCTGCCCGACCACGTCCGCGGAGACCGTGGCGGTGGCCCGTACCCCGGCGCTGACCCGGATGCCCTGGTAGCGGGGAACCTCGACGCGGACCCGCACGCTCAGCAGGCGCCGGCCGTCCAGCTCCTGACGGATGTCCTCGCCGACCGCCTCCGGCAGTCGGAGATCGTCGAGCCCGAGGTGCCGGGGCGACCGCGCGGTCGCCGGCACCACCAGCAGCCGGACCGGCCCGCCCGGCTCGTCCGGCGGGAGGCAGCGGGCCCGCGCCACGCCGGAGACCTCGGTGGTGAACCGCTCGAAGTCGGCCGCGGTGACCGCCCGGTCGGCGCTGCGCAGCGCCAGCGGCCCGCGGATCCGGGCGTTGTCCGTGGTCTCCGGGTCGGCGCCGCCCGTGGCGGCCTCCGGGTTGGTGACCGTGCGCAGCTGCGGCACGGCGGAGAGCGGCACCGTGAGTTTTCCGGCGCCCACGTTGCCGCGCGCCCCGCCGCCGAACCGGTATCCGGTGACCCGGATCTGCGCGTTCTCCGGCGGCACGGCTCCGAAACTGCGGGCCTGGCCGTGCCGGTCGATGACCCGCGGGCCGAACCGGATCTCGCCGGTGGCGCCGCACCAGGTGAGATGCCGGTCGTCCGGTCCGGCGCCGGCGAACGACGCCACCTCGGTCCACTCCTCGGGTTGGCCGGCACCGTTGCCGGGGACCACCAGCACGGTCTCGCCGTCGGCCCGGGGTAGCACGGGTGCGCGGCGGACCACGAACGTCTGCCCGGGCCGGCCGTCGCTGACTCCGAGCAGCTCGCCCGGCGCGGGCTCGGCGTGCAGGGCCGGCGCCAGCCCGCCGTAGCCCCCGATCGCCACCGACCGCAGGATCGGCGAGGTCCGGTATCCGGTCTGCCCGGCGGCCGGGCGCAGCACGCAGCGCAGCCAGTGCGCCGGCACGCCCCCGATCACCAGCTCACCCTGCACCGGGCCGATCAGCATCTCGACGGTCCCGGGGCGGTTCAGGCCGCCGGTCGTGTCGGTGAGTACCCGTACGTCCTCCCACCCGCCCCCGTTCCAGTACTGCCAGACGATCGGGGCGTGCTCCGGGTCGATGCCGGCGCCGTGCGCGCCCGCGACGGCGAGGTCGAGCTGCAGCAGGTTGCCGCCGTGGTCCGCGCTCAGGCCGAGGTAGAGCGCGTCGCCGGCGGCCACCCCGGGGAAGACCGCGATGCGCGCCTCCCCGGCTCGCAGCTCACCGGTGTGGTCGGTGTCGGTCCCGCCGGTCCTGGTCCGGCACGCGATCACCTCGGGGACAGTGACCCGCAGGTCCGCGTCGGTCATGAAGACGACCTGGTCACCGTCGCGGCCGCGCGCGGTGCCGACCCGGGTGCCGCGCGGGACGACGACCGTGTCCCGAGCCGGTCCATCGAGGCGGAAGAGCAGGCCGGTACGGGCCGGGGTCGCGGAGGCGAGCGTGATGCCGACCAGTTCGAGGAACTTGAGGTAGAGCCGGTCCGGCACCTGGTTCAGCCGGTAGATGGTCATCTCGGTCATCCAGGCGAACAATTCGATCAGCGCGACGCCGGGATCGGAGACGTTGTGGTCGGTCCACGCCGGGCAGGCGGCGGCGACCCGGCGCTTGGCCTCGTCGACGATGTCCTGGAACGTGCGGTCGTCCAGGTCGGGCGCGGGCAGGCTCACTCGGTCGGCTCCTCACCGGGGATCACGTAGAACGGGTAGACCAGGTTGCGGCGGTCATTGGTGGCCCGGACCCGGTAGCCGACGGTGACCAGCACGGCGGCCTCGCCGTCCGCGGAGGCGGTCACGTCCTCGACCACGATCCGGGGCTCCCAGCGGGCCAGGGCCTCCCGGGCGGCCTGCTCGATCAGCCCGAGCGTCGCCGGGTTGACCGGCGCGAAGACCTGCTCCCAGAGCGCGCAGCCGAAGTCCGGGCGCATCACCCGCTCGCCCGGCGCGGTGCCGAGGATCATGCGGATCGCGCCGTCCAGCTCGTCGCCGCCCCGGGCCAGGCGCACCCCGCCCGCGGGCGTCACCCCGGCGGGGAATGCCCAGCCGGCGCCGATCAGGTCGCTCATCCCGCCACCACGCCCGGCGAGCCCGCGGTGATCGTGGCGGGCGCACCCGGGACGTCACAGCAGGTCGTCACCGGGTCGCCCAGCCGTGCCAGGCCCGCGCCGTTGACCAGCACGGTCAGCGAGCCGCTCAGTACGGTGCCCCGATTGAGCGGCGGGTTGACGAAGCCCGTGCCGGGCGGGACCGGCAGGTGTCCCGGACTGTTGACCACCCCGCTGCCCACGACGGCGGCCGGTCGCCCGTCGATCAGCACGTCCGGGGAGAGCCCACTGACGAGCGTCCCGGCGAAGGGCAGCGGCTGCGGTACGGGCACCGGCCCGCCCGGCCCGGGCACCAGCACGAGGTGGGTGTCGGTCCCGGTGACCGGGTCGCCCTCCCGGGCCGCGTTCGGCATGGGTGTCTCTCCCTGAGGTCTCAGTTGAGCCGGATCGGCCGGCCGGCGGCGCGCAGCTCGGCGTCCGCGGTGATCTCGACGGTCGGCGCGCGCAGCACGAGCCGGTCGGTGGCGGCGATCTCGATCGTGCGCCCGGTGACCTTCAGGGCGCCGGCGACCCGCAGCGCCGATTCGTCCCCGGTCAGGCGCAGCGCCGAGTCGCCCCCGGACAGCGCCAGCTCCACCGCGCCGGGGCTGTCGTCGTCGAAGGTGAGCCGGTGGTCGCAGCGGCTCGCGAGCACCCGCCGGGTCGCCGCGCCGTCGCGGGCCACGTCCGGATCCGGCGGCACGTCACGGCGGTTGAAAAGACCACCGAGGACGTACGGGCGGGTCCGGTCATCGAGCTCGAACCCGACCAGCACCTCGTCCTCGACCTCCGGCAGCCACTGCATGCCCCGGCCCGGACCGCCTCCCGGCGTCACGACCCGGGCCCAGGCGCTCTCGTCCTGCTCGGACAGGGTCGGGAAGCGTACGCGTACGCGGCCGAGCTTTTCCGGATCGGCGTTCGAGGTCACCACGGCACTGATCAGCGACCGCGGCTCGGCGCCGGGCGCCGGGCGCAGCAGGTCGGCCAGCTCACCCGCGTCCCGGGTGCCGCAGACGAACCTGGTCAGGTACGGGCCGCCGGCCCCGAAGTCGTGCTCGGCCGAGGTCACCCGGTAGCCGCCGGCCAGCCGCTGCCCGACCCGCTCCAGCTGCACCCGGGCCCCGGCCGCGATCAGCGGGTTGCCCTTCGCGAGGCCGCGCAGCACCACCTCGGACCCGGAGGCCTTCGACAACAGCGATCGGGCGTAGGCCTCCGCCTCGGCCAGCCCGCTCGCCGGCACCTGTCCGGTCCGGCGGACGGTACGGCCGAACGCGCCCCGGGCGGCCTCCGCCGACTGGGCGGCGGCCGGCGCGTCGGTGCCGTACTCCGGCTCGGCCGCCCGTCCGGTCACCGTCCGCTTCTCCACCGGGTCCCAGGCGGTCACCACGACCTCGTCGCAGTGCTCGGCCGAGGCGAACCGGGCGCTGAAGTCGAGCAGGTTGTCGCCCCAGCGCATCGGGGGCGGCGTGACCCGGCTCGACGGGCGGCGCTTGAAGTGCAGCGTCCCACCGGTGACCCAGACGTCGAACCCGGTCCGGGCGGCCAGCCCGCGCAGGAACGCGAGGTCGGTCTCGGCGATCTGCAGCACGTAGTCCTGCGCGGCGCCGGTCGCGTCCACATCGGCGTCCAAGCCGTGGTCGGCGGCGATCCGGGCGGCGACATCGCCGTCCGACATGCCGGTGAAACTGCGGGTCCGCGGGCCGCGCGCGAGCCGGTGCGCCAGGTCCAGGCCGGTGAGCACCAGCTCGTGACGTCCGGAGACGCCGGGCGCCACCTCGACCGTGGTGACCTCCCCGGAGGTCACCACCACCGGGTCGGCGTCGGACCGGAACGCGATCTCCACCCGTGTGCCGGGACGGAACCGGTGCTGGTCGAAGAGCTGGAAGTGGGCGTCCTCGAACCGGATCGTGAACTGGTCGGGCAGGTGGATCGACTCCTGGACCCGGACCCGGATCAGCCGGGGATAGAGCGAGGTCGGCAGCGGCGCACCGTCGACGGTGATCGCCACGGTGTCGAGCCCCCGGTCAGCGGTCACGGCGTACCGGCCTCTCCGGGATCACCAGCGAGGTGCCGGCCGGCAGATCCAGCGGGTCCAGGACGCCGTTCGCCGCCGCGATCAGCCGCCATTGGCCGGGATCGGCGTATCGCGCGGCGGCGATCCGGTCGAGCGTCTCTCCGGGCCGGACCACGTGGACGGAGTGCGGCGCGGGGGTGTGCGACGTGGGGTTCTGCAGGGGATGCTCGTGCTCGTCCTGAAGCTGGCGCAGGGTGAGGTCGGCCTTGGCGCGCAGCGGCCGTCCGCTGGACGCGAAGTAGGTGTACCGCACCTGCAGCCGGTCGATCACCGCGCGGAAACTGTGCAGCTCACCCCAGTGGAACTTCACCCAGGGCGGGCGGCCGGAGGCGCGCGCCGGGTCGTTCGACGGCAGATCGGGATCGACCCGGAGCAGATTCAACAATTTCGAGGTGTACGAGGTTACGTCGCCTCCCGTCCTGGTGGTGTCGAACACCAGGCTGAGCGCGATGGTCGCCGACTGGCCGGCCTGGAACCGCAGCAGCGGCGCGTCGACGCCCTTCGCTTCCCCGGCCTGCCAGGTGTTCGCCTTCACGACGGTCAGCTCGGCCGGGTTGAACAGGCAGTCGATCCGCTCGCCGGTGCGCTCGACCTCGATGTAGGCCTTGGCGGGCTGGTCCACGCTCTCCCTCCTCCCCTCTTGATCAGAACAACGACGAGAACCGGCCGCCGCGACGCTCCACCTGGTCCAGGACCCGCTCTTCCACCGCGCGGATGATCTCGTCGACGCCCCGTTCGCGGGCGCCCGGTTCGTGTCCCGGATTCGGGCCGGGAACCGGCGCCGCCTCGACGACCGCCGCGGCCGGGTCGGCCGGCCCGGCCGGTGTGCCGGTGGGGCGGCCCGGGGCGAGGACCGGGCCGGTGTCCCAGGTCGGGGGGAGGCCGGGCGTCCCGGCTGTCCCGGTGTCCAGGACCGCTCGGGCGGCCTCCTCGGCGGCGCGGACCGCCGCCTCGATCAGGGCGGGCATCGCCGCGGCGCCGGTGCCGACCGGCAGCGCCGAGACGCTGCCGGCAGACAGGGCGGCGAGGTGGCCGGCAGCCGGTGTCGCGACGGTGCCGGAAGACGGCGCATGGCGGTCGCCGAGAGGGCGCGCCGATGCGCTGCCGAGGGGCACCGCGGCGGCCTGGCCGACCGGCAGGGACGCGACCGGCACGTCACCCGCGACGATCCGTCGCATCGTGGCCTCGTCCCGGCGGGCCGCCCGCTCGTCGGCGTCGGCCGCACCGTGCGCCGACCGCAGCGAGAAGCGCGGCCGGCCGACCGGAGTGCGGGCGTGCGCCAGCTCGTGGGCGAGCAGGCCGGGATCGACCCGGGCCGGCTCGTCGGGCAGGTGGACCGTGGCGCGCGTCGTGGCGCCGTACGCGCCGGCCGCCCGCAGGGCCAGCCGGGTGGCGCGCCCGGTGGTGTATCGCGCCGAGATCCCGCCGGTGAGCACCCTGAGCAGGGGAGACATCCGTGTGGGGAAGGGTCGGGGCGCCTCGAGCGGCAGCCGTGCCACGGCGGCCCGCCAGCGTTGCTCAGCGGAACCGGCGGGATGCCGCGACCGAGCCGGACCGGGGGACCGAGCCGGGCCGGGGGACCGAGCCGGGCCGGGGGACCCGGCGGGCCCGGGGTGACCGGTGGACCCGTGGGGGCCGGCGGCGCCATGGGGGCCACCGGACCCCTCGGCCTTCGCGGGCCCGGCGGAACCGGCGTGCCGGGGATACCGGGACGCCGCGGGCCGGACATCGAAACGCGCGATCGCCCCCGCGACCACCCGGCCCCGGCGGACGGCACGCCGCGCCGGCCGGCCGAGACCGGGCACGGCGCGACCGCACAGGGCGAGCCGTCGAGGGCCGGCGCTCCGGTGTCCGCTCGCGACCGGACCGGCGGCTAGGGCACGTCGAGGGCCGGAGGGCGCCGCCGCCGCGAAGGCCGGCTCCGGTGGCGGCGCGAATCCACCCGCCACCCGGAGCCCGGCGACCGCCCCCACCTCGATCAGCGGCCCCGGCCCACGCCGTGCGGGCGTGGCCGGACGATCAATCCCGGATGTCCGGCAGCCACGGCCGGCAGCGATCCGATCATGCGCCGGCTCGTGACGAGGGGGCCGCCGACCGGCCGGCTGCCGGGCCCGGCCGAGCGGCATCCGGTCCGCCGGGGACGGCAGACGTCCGGCCCGCAGCCGCCGCAGCAGCAGCACACCGGCCAGCCACCGGGGCCGGCGCACCGGGACGACCGCGATCAGCGGCGAGGCGTGCGTGCGGCGCGACCGGTCAGCGACCGGCCGCCATCGTGAAACCACTGTGGCAGACCTCCAACTCCTCGACGGCCAGGTCCCGGGAGGTCGCGGCCAGCCTCGGCCCGGTCCACCGCACCGGATACGCGTCGGTGAACCGCCATGTCTGTACGGCACGGCCACGGCCGTCACGAATGGCGACCTCGCCGTTGCGGACGTCAAGCTGGTTGCCTTTGCGGGTGAAACCCTCACCCGAGCAGGAGGTGAACCAGCCGAAGAGGTTGCCGGCGTTGGTGAGGCCACGCTTGAGCACCAGGTTCGGCCATTTCATCCGGCCGGGCAGCTTGTGCGTGTGCTGGTTCTGCCCACCCTCGGTGATCTCCTCCACCTCGATGGTCACGCTCAGGCCACCGACCTCGACGAACGTGCCGATCTCCAGGCCGTCGACGCTCAGCACGAACCGTCCGGTCCACGGCGGGTCCGGGACACGGTGGTCACCGGGCAGCAAGGATTCCCTCCCAGGATCGTTCGTTCAGGTCGGCGACCTGGCGCACCAGGCGCAGACGGTCACCGTGCTCCAGGTCGAGCAGGGCGTCGAAGCCCCAGTGCAGGTGGTACGCCAGGTACGCGACCTCCTGCCACAGCTCCGGTTCGGCGTAGCGGCCTAGACCACCTCCACCGAGACCCGGGGGAAAGGGGCGCCGGGCTCCAGGGCGTCGAGCGCGGCGGGATCCCCGAAGTTGATCAGTTGGTAGAAGTCCTGCAGGTAGCCGAAGTCGCTGGCGAAGAGCCGCTCGATCACTCCCGTGTTGATCCGGGGCAGCGTGCCGAGTTCGGTCACCACCCGCGCCAGCACGATGACCGTGGCGTAGGACTCGTTCTCCCGCACCCGGGGGTCGCGCAGCGGCTCGATCTCGTCCCGGGCGGTGGCCAGCCGCATCACGCCGGTGCGGTGCAGCGTGCCCTCCTCGTCGACGTAGCCCTTCGGCAGCGTGAACGGGAACTCGGTGTGCAGGCTCATTTGACGCGGACCAGCCCCTCGTGCGTGATGACGACCTTCTCGGTGGCGATGTCGTTGGCGCCGGCGTCGAAGTCGGCGCCGGTCCACTTCGACGGCCAGCCCGCGACGAACTCCCAGCGGGCCACGACGTCGCCCTTGGAGTCCTTGGCCGAGATGGCGCCGTTGCGGCGGCCCTTGTCGACGTCGCCCGTGATGATGTCCTTGCGCCAGTTCCAGAGCACCTGGGAGACGTCGATCCGGCGTTCCAGGGTGATGTCCGCCCACTTCATCGCGCCCGGCTGCTTGCGGATGATCATCTTGCCGTCCTTGTTCACCTCCTTGTACTCGATCGTCTCGGTCTCCGACTCGATCCCGGAGACCTTGCGGAAGCTGCCCACCTCGACGCTGTCGATCTCGAGGACGAAGGTCTGCGTGGTGATCAGATCCACCATGGAACTGCCCCTCTCTACTCGGCGGTGGCTACGCCGCCCTGCCACTGGCTGATCCGGAAGATGACGTATTCGGCCGGCTTGACGGGAGCGAGCCCCACGTCGACCACGAGCAGCCCGTTGTCGACCGAGCCCGGCGGATTGTTCGTCTCGTCGCAGGTAACGAAGAAGGCCTGCTCAGGCGAGGCGCCGACGAGGGCGCCGCGCATCCACAACTGGTGCAGGAACGCGCCGATGGTCCGCTTCGCCCGGCCCCACAGCGCCTCGTCGTTCGGCTCGAACACGCACCACTGGGTGCCCTGCCGGATCGTCTCCTCGACGTAGATGAACAGCCGGCGGACGTTGATGTAGCGCCAGGCCTGGTCCTGTGAAGCGAGCGTGCGCGCGCCCCACACCCGCATGCCGTTGGCGCCGAACGAGCGCAGACAGTTGATCTGACTCGGGTTGAGCAGGTCCTGCTCGCCGGTGGTCACCTCGGTCTCCAGCCGGGCCACCCCGCGCAGGGCCTCGTTCGCGGGCGCCTTCCACACGCCGCGGGCGCCGTCGGTGCGGGCCCACACTCCGGCCACGTGTCCGCTGGGCGGGATCCGCAGGTATCGGTCGGCAGCGGTCGAACCGGGCCGGGCGTTCGGATTCGCGACGATCAGGTGCGGGTAGTACGCGGCCCCGAACGCGGTGTCGTGCTTGAGCCGGTCACGCCACTCCAGTGCCTGCTGCGCCGTGAGGCCCGGCGGCAGGTCCAGCACGGCCATCGTCGTACGCCGCTGCTCGCACCAGTCCAGCAGCCGGGCCTGCGCCTCCAGATAGGCGGTCTGGTCGATCCCGCCGTCCGGCCGGCGGACCACGGTCACCAGGTCGGGGATCGCGACGATCGAGACCTCCTCGGCGATGGCCAGCCCGTGGTAGCCGGTCCGCTCGGTCTCCGATCCGGCCAGGTCACCGGTGGTCGCCGTGGCCGCCGACGGCGCCGGCTCGACCAGATAGGTGCCCGCCGCCGGGATACGCTCGGCCGGGGACAGCCCCGCCACCGTCCGGGCCTCGACCCGGATCAGCGTGGATCGTTCGTTGATCGTGCGGACCGCGGCCGAGGTGCCCTTGCCGGTGCCGAACGTCAGCCGCGGGTACGTCTCGGTCTGACCGCCGGCCCGGTCCACGGTGAGGCTGAACTCCTGCGGCGCCTCGCCCTCGACGGCCGGCGGCTCGTGGACGACCGTCACCTCCACCGGCGCACCCGGCTCGCGCGCCTCGATGACCAGCGAATCGGCCTCCTCCCGGCCGGTCGCGGGCAGGGACCGGCGCGCCGGGCGCACCGATCGCACCGGGATGCGCACCACGTAGCACGCGGAGCCGCCGTTGGCGAAGAACCCGTGCACGGCGTGCGGCAGCATGATCCCGGGAGCGAATCCGCCGTAGATCCGCTCGTACTGCGGCCAGCTCGTCACCAGCTGCGGCTTGATTCCCTCCGGATCCGAGTCGTCGCCCTGCGCCGCGTCGTACCGTTCGGTGAAGCCCACGAACGCGGCCACGGACGTGCCGACGCCTTGCAGCGGCATGGAACCGCTGACCTGCTCCTCGATGTAGACACCGGGAGCACCCCCTACTGCCAT

Protein sequences of DBSCAN-SWA_1

>NZ_LT827010|2333775:2384758|2369732_2370413_+|WP_043513908.1|DBSCAN-SWA
MRLLVIEDEPELATILQRGLTAEGYTVDVAGDGRVALDLARFEDYAGIVLDLMLPGLNGYRVCATLRREGIRTPILVLTAKDGDYDQIEALDTGADDFLSKPFSYPVLVARLRALVRRGPAAVPVRLTVGDLVLERAARTCRRGTVPITLTPREFAILDLLAHRAGEPVTKLEILRQVWPEDVDDPNLVEVRVGRLRRKIDLPFGRSSLRTVRGTGYRLVDDRAAA
>NZ_LT827010|2333775:2384758|2343305_2344634_-|WP_014689152.1|DBSCAN-SWA
MTAPFTQPTAEEFRAATTELRELNAPYARERLIFRPPVESPGQVRRLEAACQTVFEGLDAVLREVCGGDVLRMARLCRATEPELQFLTHQTDQNWSTVARPDVISSGGRTVVVEINGDSPAGLFGLHDIIARAQAAFQRPAPQAPARPAVAMRGLLDSLERSFGRLTGTVAICYWRHEQQAGPLDWQYELFARELRRHGVDAVHCALEDLRMDDAGVAYQGRPVQVIYRYFESPEPTEHDEFTLLKQLFALAGAGLVGLFTGYRAEVLASKAALAVLSDETVVDRLDADLRDRLAAHVPWTRVLEPRRTTVEGADVDLLPWVAANRERLIVKPVRGHAGKGITVGREVSARAWAEAVGAGVRGGAGDHPYIVQQVFEPDRLPVAFTDATGRATVTETPSVNGVFIVDGRAVAVLRRYAVNATGTININPFSGYAPSPVWTAS
>NZ_LT827010|2333775:2384758|2366187_2366817_+|WP_014689170.1|DBSCAN-SWA
MSATWEQPQPWAVPLVSVSLGGGEARTCRVTRQADGTLRLGLTGFAMIGVDATLLWTQNNRGCSIDGTVIAPPAGSLPGVYLRVDGAAGGIQRRRTERVRVQLPAAVRLPSGQLFPGRTVDLSAGGAHVTVDLEEIGDEALIRLVEDLERDVLIEVQIGLPDGLAGITCQVRAGGDEPGDVRLLFINMNPEVRARVVRFVEASAPAVVG
>NZ_LT827010|2333775:2384758|2336237_2337305_+|WP_014689145.1|DBSCAN-SWA
MPNMKAVQLLAPRKTVLAEVPVPATPADGLLLKTRCVSICSTDISFFEGHLFPSEYPVILGHEYLGEVVDIGPEFDGGGVDVRIGDRIVYWGQTDYGGFAEYRSLRPIFSGQILEDVFWADRHFFDDDRAAAVKVPDDLSDLEASFIEPTTGALRSVLTNPPQVGDRVLILGTGPIGIIAGSVIQRLLAPNRIVSMDANPARNQHAEEHFSQHAYLPHELIDTVPESTFDYVFDTLPTISGVPEENDPRRVAMRKLKPGGHYVLYGASQEMQKFDTWLMLAKGIRISAAPFDVTHFPMHKTANVITSAMQMLRSRIVDGRRLLSHVCRFDDYDGLVDVLENYRHTTSLKTIVDFR
>NZ_LT827010|2333775:2384758|2361285_2361729_+|WP_014689165.1|DBSCAN-SWA
MTRDDAGAALADLADLILNVGRLVRARTPDESPDVVPLTETERQVMRIVDLHPGAAPSEIARRTRLQRTNVSTALRGLEGKGMVSRAATAGRGVAVHPTELAAANLRVLRAAWARELAGDLGDDLDAVRRCTDLLGRLERQLTADEP
>NZ_LT827010|2333775:2384758|2376995_2377394_-|WP_014689182.1|DBSCAN-SWA
MSDLIGAGWAFPAGVTPAGGVRLARGGDELDGAIRMILGTAPGERVMRPDFGCALWEQVFAPVNPATLGLIEQAAREALARWEPRIVVEDVTASADGEAAVLVTVGYRVRATNDRRNLVYPFYVIPGEEPTE
>NZ_LT827010|2333775:2384758|2361741_2362887_-|WP_014689166.1|DBSCAN-SWA
MRHIRIKGAPTGLERGVTIDPAPLFTPYKIGDIDLANRFVMAPMTRQFSPGGVPGEDVAAYYARRAPHVGLIVTEGTYVDHPSAGSSDRVPRFYGADALAGWRAVAEAVHAAGGRIVPQLWHLGATRAAGAPPHPEAPVLSPSGRRADGTVVGEPATTADLDAVVAAFATAARDAQLAGFDGVELHGAHGYLLDQFLWAGTNHRGDGYGGSLANRARLGAEVVAAVRATVGPDFPVLFRFSQWKGTHFDARIADTPGELEQILAPLVDAGVTGLHVSTRRYWTAAFEGSPLTLAGWTRKVTGLPVVAIGSVGVAQAFRGETEEPAPTLSVAPLLELFERGEFDLVGLGRALLSEPAWPTKLRAGRLADIRPYDKADEARLS
>NZ_LT827010|2333775:2384758|2367786_2368224_+|WP_014689172.1|DBSCAN-SWA
MSSRQFVTFEVAGQFFGVDVDAVQEVLSYSEYTPVPMAPTAVGGLFNLRGQVIAAVDLRVQFGLPRRDMTGLVMNVIVRHDGEPVSLLVDRIGQVAYLDAQMFEEPPATLTGPSRALVTGAYKTEGRLLLVLDVAECVNTSRVTA
>NZ_LT827010|2333775:2384758|2382719_2383154_-|WP_014689190.1|tail|DBSCAN-SWA
MVDLITTQTFVLEIDSVEVGSFRKVSGIESETETIEYKEVNKDGKMIIRKQPGAMKWADITLERRIDVSQVLWNWRKDIITGDVDKGRRNGAISAKDSKGDVVARWEFVAGWPSKWTGADFDAGANDIATEKVVITHEGLVRVK
>NZ_LT827010|2333775:2384758|2374143_2374494_-|WP_014689179.1|DBSCAN-SWA
MEPDDRMLRLPRTPGQEADTGGRSAARDDRLRPPEKRVPGPRCPDCGHGNPTARVRCEVCGAELWPTAATRPSPPLAPPDPAPTVSPDRRPALVLLLVPLAVTGAIFLLAYFLIRH
>NZ_LT827010|2333775:2384758|2381739_2382207_-|WP_099344031.1|tail|DBSCAN-SWA
MPGDHRVPDPPWTGRFVLSVDGLEIGTFVEVGGLSVTIEVEEITEGGQNQHTHKLPGRMKWPNLVLKRGLTNAGNLFGWFTSCSGEGFTRKGNQLDVRNGEVAIRDGRGRAVQTWRFTDAYPVRWTGPRLAATSRDLAVEELEVCHSGFTMAAGR
>NZ_LT827010|2333775:2384758|2341242_2342052_+|WP_014689150.1|DBSCAN-SWA
MIWFITGASRGFGREWAAAALRRGDRVAGTARQPCDLAGLAEEFPETFLPLRLDVTDRPAAVEAVRRAAAHFGGLDVVVNNAGYGHFGMVEELAEEEIRAQLETNVLGLLWVTQAALPILRVRGGGHIIQVSSIGGLVAFPGLGAYSASKFAVEGLTQSLAQEVAAQGIRVTLVEPSGFRTDWAGRSARHSAESPEYDLVRAARDRRPTARRVGDPRASAAALLAVVDDPRPPLRVFFGSAPLDIVTREYEDRLETWQAWQHLAVAAES
>NZ_LT827010|2333775:2384758|2363537_2364662_-|WP_014689168.1|DBSCAN-SWA
MTAAEVGNSRTVPAGAARTWRVAVHTLAGLPLGVLGLALTGVLPVGAVYCAGWSLLYAGPGDWPATAGFVLLAVVAPGLAPEAARRLTGVQRRRFRVLLGADIPPPVRPARGRQIAYHLLACFTGVAFAVLVLVAPWTAARVARADTALARALLGPGRRAELSMRVESLARSRADVVAATDAERRRIERDLHDGAQQRLVSLAMNLGMARATLAGTSGPAMRAIEDAHDEAVQALAEMREFVRGLHPAVLDDRGLDAALSGIAARAPLPVRLLVDVPARCSPVVEAIAYFVVSEALTNVSKHAGATRAEVIVERAADRLRVVVTDDGRGGATTGGDGTGLVGLARRAAAVDGTFALHSPTGGPTTITVELPCGS
>NZ_LT827010|2333775:2384758|2345492_2346695_-|WP_014689154.1|DBSCAN-SWA
MTTAPPVPANLSRAGLIQEYDRDRLGFVMDAVRRFGPVTELSPGTVLVADGEVAHDVLRRTNRDFLMDRDRAWRPTGSRRGEDALESWMSARRAMLSALSGGLVAEHLSWYSGELTGLLDAWAARGGTGDPLTPLVRLSTDAFLRLCAGPSSRGADRREPAAAVAGLLDSLTPIVGSSYELPWFLDRLTPRRRRAVRAQHRLAESLGALVDRAPSGGLVAALRDAGVPREPLVRILISATIAGRLVPAAATAWTLRALAVHQPDDEPAHIVDEVLRLWPPTWLIHRTTHGEEISGDWRFPARTAVMICPYAIHRDERHFPDPAAFRPARWRDGRLPAGAYLPFGGGPRWCVGTHLAKAQLVEAVRVFRRYRLTDTSDAVTLDTRSTLYPRGLALGVGRPA
>NZ_LT827010|2333775:2384758|2350688_2351597_+|WP_014689158.1|DBSCAN-SWA
MTTDTESVVVGAPPAPRSVSRNRLVLRRFLRQRLAVVGLIVVVLMVLIAYLGPLFYKWKYDQLDFEAFQSPPTPEHWFGTYQTGGDVFSRTLRGLQKSLVIGLLGAGASTALAAVAGAFAGYFRGSTDMVIRVIIDLMLVLPSFLIIAIFSTALRDGSWLLFIVLLAGFQWMITARVVRGITQSLREREFVQAARFMGVPGWKIILRHILPNMASLLIIDATVGVSSIILAEVGLSFFGFGVQPPDVSLGTLIADGSGAALTNWWQFYFVAGVLVLLVLAVNLVGDGLRDALDPNSEIEGAK
>NZ_LT827010|2333775:2384758|2342067_2343309_-|WP_014689151.1|DBSCAN-SWA
MRWHPAPTLFAAGASASLGDGIRYAAFPLLAVHVTTNPISVGAVSAALSAAHLLFGFHVGAAVDRFDRVRLLRSMQLTRLAVVLVLFGAVLTGTASLPLLLVTAFLLGAAELAADTAVQSLTPVVVRDAGLERLNAGLTAAQSIGEDFAGPAAGGLLFSLSPAAPFAVFAAAIGGSWAVLTRLRVPGRVAPPPGDRPSLTAEAREGFRYLVHHPSLRAQALWATAMNLGVAAANATLVLYVVQRLHLGDSAYGLLLTGAGIGGVAGAVASPWTIRLLGRLGTMITASLVAGVVTLGIACTTSVAVIVGCQFLAGFSGVSFSVVGRSLRQSITPDALMGRVTGIYRLIGFGSLPLGALAGGAVAHWLGLRTPFLLAGALMVVSTLTLGLLTRRAQPPAATTAATAGRQVAGVPG
>NZ_LT827010|2333775:2384758|2379436_2380108_-|WP_014689185.1|DBSCAN-SWA
MDQPAKAYIEVERTGERIDCLFNPAELTVVKANTWQAGEAKGVDAPLLRFQAGQSATIALSLVFDTTRTGGDVTSYTSKLLNLLRVDPDLPSNDPARASGRPPWVKFHWGELHSFRAVIDRLQVRYTYFASSGRPLRAKADLTLRQLQDEHEHPLQNPTSHTPAPHSVHVVRPGETLDRIAAARYADPGQWRLIAAANGVLDPLDLPAGTSLVIPERPVRRDR
>NZ_LT827010|2333775:2384758|2373288_2373636_-|WP_043511166.1|DBSCAN-SWA
MTEPMRDPSFWVLTALAPEPRHGYGVIREVNRLSDGQVTLQAGTLYAALDRLTSLGLIEADREETVDGRPRRYYRLTTDGAAALDAETERRRAAVAAATAQLSARRRLGLSLSTS
>NZ_LT827010|2333775:2384758|2338781_2339288_+|WP_014689147.1|DBSCAN-SWA
MSVTTSDFTSLMARVPGPVVVATTVDPDGRRWGFTASAFSSLSLSPPLVLLCLAKSASTHAAFVRAERFLVNVLAADQAAVAARFARSGEDRFAAGDMRPYELGLPGLPGAAARAACALDSVLEGGDHSILVGRVLAVTVAEPAPLVHCDRAFARPVPLDQLAVARSR
>NZ_LT827010|2333775:2384758|2335032_2336208_+|WP_014689144.1|DBSCAN-SWA
MLWEPPETGEQSEWLSRVAALAPLIERHRAEADRERRTPQAVFEALRDAGIPRMWVSTEFGGGQVGLHTGSLVIQALARLDASVAWQMGVQGAIGRISDYLPEQTARELFKQSGGLVVGAVNPAGRAEETAGGYRISGRWGFASGSAFADWLVCAAPVHRDGQPVLRGSAPELRMLFVPVSAVRLLDNWHTLGLRGTGSNDFEADDVFVPAEYTVDQAAMLRPPAGRFSRAYPIGYYDFGPFTSASTAAGVARDAVATVTELVRGKVQTGGSGSLARSHVVQDRLARATMHVHTARTLLRDTAERVTESGESGGERLTATVRLTAATVAELAVQAVDIAYDLAGSTSLYETSRLERAFRDVHSAVKHITLAPQHFEMVGQYLVGGELRVRR
>NZ_LT827010|2333775:2384758|2358340_2359918_-|WP_043511159.1|DBSCAN-SWA
MLAVTNRRVGTKILLAVATMAIATVAVGIAAISGMRQMRAAADYVYQQNLVPITQVTAMQRSAGVTKASLLTAALSRQGVEARFDQGEDAAFDAAFAAYTSSDMRGREAEVATVSDAVHTYRKLRDEQLLPAIRNHDRAAFVSVWGGAMTTTSDRLDGSLQKLVGIETGVAREKNAATADTFRQAVIVLGVVSVVGMIAAGLFGAAVAGSISRRLNRCVTVLRSIADGDLTARTEVTGSDEVAGLAATLDRTTAATAAMVGGMADDAAFFGSASQQLSEVSTHLSTAAEQTSGRAVAVSAAAEEVCRHVQTVAAGAEQMGASIAEIASNATEAARVSARASSSAERTNDVLAQLDHSSAEIGDVVTIINVIAQQTNLLALNATIEAARVGEAGKGFAVVAGEVKTLAQETAKATQDISERVAAIQRDAAEALTAVAEIAEVTGQINSYAGTIAAAVEEQSATTAEMARSVAHAATGSSDIAVAVAEVAEVAAGTATSATQTRATAGGLAERAGVLQRTATSYRTA
>NZ_LT827010|2333775:2384758|2375055_2376999_-|WP_014689181.1|plate|DBSCAN-SWA
MSLPAPDLDDRTFQDIVDEAKRRVAAACPAWTDHNVSDPGVALIELFAWMTEMTIYRLNQVPDRLYLKFLELVGITLASATPARTGLLFRLDGPARDTVVVPRGTRVGTARGRDGDQVVFMTDADLRVTVPEVIACRTRTGGTDTDHTGELRAGEARIAVFPGVAAGDALYLGLSADHGGNLLQLDLAVAGAHGAGIDPEHAPIVWQYWNGGGWEDVRVLTDTTGGLNRPGTVEMLIGPVQGELVIGGVPAHWLRCVLRPAAGQTGYRTSPILRSVAIGGYGGLAPALHAEPAPGELLGVSDGRPGQTFVVRRAPVLPRADGETVLVVPGNGAGQPEEWTEVASFAGAGPDDRHLTWCGATGEIRFGPRVIDRHGQARSFGAVPPENAQIRVTGYRFGGGARGNVGAGKLTVPLSAVPQLRTVTNPEAATGGADPETTDNARIRGPLALRSADRAVTAADFERFTTEVSGVARARCLPPDEPGGPVRLLVVPATARSPRHLGLDDLRLPEAVGEDIRQELDGRRLLSVRVRVEVPRYQGIRVSAGVRATATVSADVVGQDAEDALYRFLDPVAGGPGGHGWPFERALGVGDIYLVLGAVPGVAAVTSVNLTLTDLWGEREDAPGGQEVPLVPSALFLSDRHTVAVAW
>NZ_LT827010|2333775:2384758|2377806_2379447_-|WP_014689184.1|DBSCAN-SWA
MTADRGLDTVAITVDGAPLPTSLYPRLIRVRVQESIHLPDQFTIRFEDAHFQLFDQHRFRPGTRVEIAFRSDADPVVVTSGEVTTVEVAPGVSGRHELVLTGLDLAHRLARGPRTRSFTGMSDGDVAARIAADHGLDADVDATGAAQDYVLQIAETDLAFLRGLAARTGFDVWVTGGTLHFKRRPSSRVTPPPMRWGDNLLDFSARFASAEHCDEVVVTAWDPVEKRTVTGRAAEPEYGTDAPAAAQSAEAARGAFGRTVRRTGQVPASGLAEAEAYARSLLSKASGSEVVLRGLAKGNPLIAAGARVQLERVGQRLAGGYRVTSAEHDFGAGGPYLTRFVCGTRDAGELADLLRPAPGAEPRSLISAVVTSNADPEKLGRVRVRFPTLSEQDESAWARVVTPGGGPGRGMQWLPEVEDEVLVGFELDDRTRPYVLGGLFNRRDVPPDPDVARDGAATRRVLASRCDHRLTFDDDSPGAVELALSGGDSALRLTGDESALRVAGALKVTGRTIEIAATDRLVLRAPTVEITADAELRAAGRPIRLN
>NZ_LT827010|2333775:2384758|2349678_2350677_+|WP_014689157.1|DBSCAN-SWA
MGKFLLRRVGYLVVLALVATVVAYLLAATQLHPRSRYEGRNPAPAAAVVDQRLNELNMNDKTPLVERFTTWAKGVAHGDLGKTVDGESVNTEMSRRMWVSLRLMLIGSILGTLLGVVAGAYGAIKQHKWSDQTLTGISFVLLSVPTVVLAVLMKNGGIWFNQASGHESNPLVFTVGEITPGLDTWSWAGLSDRFGHLVLPTIVLAIGVNGFAFYSRYQRNSMLDVLGSDFLRTAQAKGLRRWSALTRHGLRTALIPMATFFSYQFALLFVGATFTEKIFGWHGMGEYFVDSITKNDINSTAGVTLFVAVLVLIAGLLSDVVYAMLDPRVRAS
>NZ_LT827010|2333775:2384758|2344630_2345473_-|WP_014689153.1|DBSCAN-SWA
MRVRAGRVRLHVTTIGDDWRDGVHRPTIIAVHGGPGIDGTMLRLTMLPAAEYAQVIVPDLRGHGRSDRGGPAEWTLDTWADDLAALVDTLGLEKPYLLGTSFGGFVVQRFLGRHPELAGGAILIGTGARQASHDEIVERHRVLGGDRAAAVMRRSLTDHSPEAEREWAEVCGPLAIRRAPDEAYQRVLRDRITTPEINAGFIAQLDRLDLRPDLAAAKCRVMVLVGEHDPLIPYAVAEEIVDSLPGRAGELHVVPGASHQAVWDAPAATHALIRKFTEES
>NZ_LT827010|2333775:2384758|2370409_2371864_+|WP_014689175.1|DBSCAN-SWA
MTGLRSVRARSALAAAAAAAVILTGGGLWARHFVGQQQLEAGRRSAVQQVNAMGLAATTIGTGGAEELRPAFYPDVTFEVVDTTGAVLSASPDLAPYESDGRAVMPAADPLPGDISMDTPEVSATVRLADPPGDHALDGRTVTGVRIQGAPVSMTDHPELGPTFAVYVFVTPLAAERAVATVDRILVGAVPLAVLVVALVAWFATRRALRPVEAIRARTAEVTASRLADRVEVPATGDEIAALATTINAMLDRLQRADRAQRRMVSDAAHELRSPLAILRAGLEVAQAYPDRTDWPATAATAVAQAQRLTGLADDLLLLARLDAGTAPPQPEVDADVVAVLSRMAVETITRDGVTVTGPAGPPVPVRLARVPFERIVRNLLDNAVRHAGRRVEIRITADPAAAGRTRLRVEVADDGPGIHPGDRDRIFDRFTRVDAARDRHAGGAGLGLSLARELATQLGGILRVADRPVPGATFELTLTVTAA
>NZ_LT827010|2333775:2384758|2355756_2357601_+|WP_014689161.1|DBSCAN-SWA
MNFRQSAVVVHGIHAAYIPVAYAAVTLSAVAAAVAPPRMLMFGMLAVGPAFVAATARPVAVLGVGGYALAAAFTVSTWQGLLGTADQVLRLMLIVVMTVVSWSVARHLGLLLRAATVAAQERQMLAAVVEQSADGIIVTSLDGVVTHWNGGAEQLYRQSADQVVGTGFGRFLPADRQAAFGRALASLAAGERVHLDEARRIRADGAEMLVSVAVSPIRDETGEVVATASTERDITEVKRREAEERLARERSARAARLESLGQLASGVAHDFNNLLAIILNYADFLTEEVTEDGSRDLARIRDAADRARALTGQLLLFAKQESATVEIVDLNEVVSASSELLTRTIGANISLLCRPHPQALPVSANRGRLDQILLNLVINARDAMPDGGVVLIETGRAPGRRVRMTVSDTGCGMSPEVKDRLFEPFFTTKPADRGTGLGLATVYGIVGDAGGSIQVDSTPGVGTTFEILLPLAGDTTGQEPEPDAHRPVTGHGERILLVEDDEFVRDLVVRILNGNGYQTVPLDENAAGDADVAGAAVLLSDIMLRFRSGPAIADQLRTRHPDLRVVFMSGYSDEELRHRYDLSAATGILQKPFTAVELLAAVGTALTPAVSRRG
>NZ_LT827010|2333775:2384758|2377390_2377786_-|WP_014689183.1|DBSCAN-SWA
MPNAAREGDPVTGTDTHLVLVPGPGGPVPVPQPLPFAGTLVSGLSPDVLIDGRPAAVVGSGVVNSPGHLPVPPGTGFVNPPLNRGTVLSGSLTVLVNGAGLARLGDPVTTCCDVPGAPATITAGSPGVVAG
>NZ_LT827010|2333775:2384758|2339320_2340007_-|WP_080128203.1|DBSCAN-SWA
MSRINRRDGAGDDFRSVTTTPRKWVWNLYNRFPGNGSNRFLRYGAGVAAEPFRQGAGRLCLDFTRTLRRRGHPDAVEELPTPAAVLAWVTQFGPVPATVASLPPADVQRFREAVFTLVTKGPAGCAATDLDLVNRIAAAPPPIPAVQPAGTLDWTAGDPVAATLSLVARDALDLATTPAASRIRECADPACSALFVDNSRPGTRRWCAMSACGNRAKKTAYRDRATAG
>NZ_LT827010|2333775:2384758|2353818_2355531_+|WP_014689160.1|DBSCAN-SWA
MRKPWSARAILAPVVAATLIGTAACSGSSGTTTNQAAPPPKASENQINPKSRDQVKDGGTLTWALSGFPANFNYYELDGTDVDASYVNLAMMPQLYNYEADATPVWNKNYLASEPVLKTDPKQVVTFELNPKATWNDGAPITWEDLYWQWKSTSGADKAYNISASNGYENIESVAKGKDDHEAIVTFKTKYADWQSLFTPFYPASTNKDPKTFNAGWQKSPLKTTAGPFKFDSADATAKTITLVRNEKWWGDPAKLDKIVFRAIEPNAQVDALANGEIDFVDIGSNVDAYQRALKISTAEIRKAAGPNFRHLTINGTSTVLSDVKVRQALAQAIDRTAIAKALTGPLGIDPKALNNHIFMSNQAGYQDNSGDIGKYDVEKAKAGLDAAGWKLNGDTREKDGKKLEINFVIPTGVKSSEQESQLVQNMLAQVGAKVKINAVPVDDFFDKYVTPGNFDMTVFAWIGTQFPVSSAKSIYANPTKNAKGELDIQQNYARVGSPELDTTFNNATAELDKTKAATLANQADAQIWQEVHSLTLYQRPELIATKKDLANFGAKGFASVIYENIGFVK
>NZ_LT827010|2333775:2384758|2357609_2358221_+|WP_014689162.1|DBSCAN-SWA
MAGRREHNKRETRRSLQDAARRLFEERGFDEVCVEDIATEVPVSRRTFFNYFDSKEAALVDPGPSRVDTLAALLAGRPADEPLLNSLCTVHIQFLMTDPEDLAARMRLVRANPALRQRWITAIETFDAEVVRWACTRTGLPPEAVYPQLLAGIAGTVSRLAMEHWDPDTAPERLAEVISCIYRLLAALGNDADLPPADRGCEH
>NZ_LT827010|2333775:2384758|2368248_2369637_-|WP_014689173.1|DBSCAN-SWA
MIVLSHDVVPAARATPVRRSGAVLAWSGAGGLAVIYLLLSLLNHRRLRTTGFDLGIFEQAVRSYAAGRPGLVPLKGPGFPQLGDHFSPVLALLAPLYRIFPTPVTLLVAQALLLAVAVVPIMSLAHRRLGAFAAVTAGAGYGLSWGIASAVGFDFHEVCFAVPLLSFSLAALADRRLRAASGWALPLLLVKEDLGLTVAVIGLLVAAFGARRLGGGLAAAGLLGTALAMGVVVPALNPDDAYAYSAAVGSGLQHPVTAVKLLTVLALLAPTAGVALRSPLAWVAVPTLLWRFASGNPNYWGTGFHYSAVLMPVMMLAFVDGLTRRRPAADRTGAAATRLVLVASLAVTGFLLPRYPLAQLASAPIWRGDPRGTAAHRVLDLIPDGATVSAANRLVPQLTGRTTVTLFGLDYPGPAPRYVVVDLEVDDWPLPRDIRLARVEALVAAGYRTVTRDSGFVLLERP
>NZ_LT827010|2333775:2384758|2366817_2367732_-|WP_099343733.1|DBSCAN-SWA
MRGRPKKSGGTDPEISAVRHFRRFTHGRERVELGTAVIPIGYESPFRLAEDLSLADVLSRGRLQAGFSAGTPPHAELLGPLVFDGDWRGFDLSHGRIARLADNLRGDYLGGPDTVIRSPGNTQRPRLQPHNPGLIDRLWYGVGSATSARWAGANGLNLLSGNIVAGERHDDFAAAQLHLLEEYRRDVAPGRPARVAIGRVIVPTDSADRTTRDRYRAYAASRHDRTGKPQGERRILFAPDLVGPAAEIVERLTADPVLARVSELRLELPYEFRRDDYEQILHDTVRLIAPALGRRGAAPAAARA
>NZ_LT827010|2333775:2384758|2337363_2338776_+|WP_014689146.1|DBSCAN-SWA
MEQRSYDARFVVVANRLPVQSRVAADGALLWERSPGGLVSALEPFLSRRHGAWVGWPGVAGVDVAPFTDGGTTLVPVRLSEQDVRDHYDGFANATLWPLYHDVVVRPTFDSRWWAGHVRVNERFARVAAETCAPGATVWVHDYQLQLVPEMLRRLRPDLRIGFFLHVPFPPVELFQQVPWRAEILRGMLAADLVGFQVPAAAVGFAEAAVRFAGARRAGPGSLFVEDRAVRVDAFPISVDAPAWDRVARRPEVRLRAAQIRAELGDPARVVLGVDRLDYTKGIDVRLRAIHEMLADGQIKAADTVVVQIANPARERVDQYRAVRDRVERLVSAVNGDHGRVGRPVVHYLHTMVDQAELAAFYLAADVLTVTPLRDGMNLVAKEYVASRHDGGGVLVLSEFAGAAAELPQALPVNPHHGDDVKAAFRRALELDPAEGVRRMRAMREHVFAHDLTDWAQAFLARLDDPAGEG
>NZ_LT827010|2333775:2384758|2360075_2361260_-|WP_014689164.1|DBSCAN-SWA
MSITQAPPTARHRARLALILGALSAFGALTIDMYLPAMPGMADELDAGATLVQLTLTVFVVGLAVGQVIVGPLSDAWGRRRPLLAGMALYVTGSLWCALSPTAGYLIGGRVLQSLGAAAGTVLARAIVRDLYQGTAMTRFFATLMVVNGVAPIVAPVIGGQLLTFTTWRAVFLVLAAVGAILLVTVALALPESLPRERRAPAHPRATLRAFRTLGTDRHYLRYVVAAALMFAAVFAYISGSSFVLQDAYGLSAQQFSLVFGLNGLGIVVFGQIGGMLVGRVTGEHTLLRVSLSIAVLGSAGVLVCAVAGLPLPLLLAFLFLPVAMLGIVLANATSLALAGHGSAAGAASSLQGLLQFLVGSLAASAMTLAGPATAITMGATMVICSIAALATLR
>NZ_LT827010|2333775:2384758|2380130_2380940_-|WP_014689186.1|DBSCAN-SWA
MSPLLRVLTGGISARYTTGRATRLALRAAGAYGATTRATVHLPDEPARVDPGLLAHELAHARTPVGRPRFSLRSAHGAADADERAARRDEATMRRIVAGDVPVASLPVGQAAAVPLGSASARPLGDRHAPSSGTVATPAAGHLAALSAGSVSALPVGTGAAAMPALIEAAVRAAEEAARAVLDTGTAGTPGLPPTWDTGPVLAPGRPTGTPAGPADPAAAVVEAAPVPGPNPGHEPGARERGVDEIIRAVEERVLDQVERRGGRFSSLF
>NZ_LT827010|2333775:2384758|2351608_2353735_+|WP_172898871.1|DBSCAN-SWA
MTRYPSPAGGSGAGAVEPLLRVDDLSVTFRSPAGPVTAVRGISYDVRPGEVLGIVGESGSGKSVSSLAVMGLLPDTATITGSATFEGQQLLGLGDKQLSRVRGRRLSMVFQDPLSALTPVYTVGDQIAETIRIHQDIKREAAAERAIELLDLVGIPNPRQRSKGFPHEFSGGMRQRVMIAMAIANDPALIIADEPTTALDVTIQAQILEVLQTAREATGAAIVMITHDLGVVAGFADRMLVMYAGRVVETGQVETVYQRPRMPYTMGLLGSIPRLDMGERQRLTPIDGVPPSMVDLPAGCPFAPRCPMKIQVCEETEPELLGVVIDGAGHLAACHRSPEIARKELTNVDVFPTTVVPEATGPARLPREQRPVVLEVNELVKEYPITKGGVLRRKVGSLQAVAGISFDIREGETLGLVGESGCGKTTTIMEILELAKPTSGTIAVLGKDTAAMSRKERFAIRRDLQVVFQDPLASLDPRLPVSDILAEPMATHGVPAAEREKRVRELLRLVGLRPEHADRYPAKFSGGQRQRIGIARALALEPKVLVLDEPVSALDVSIQAGVINLLEQLKVELGLSYLFVAHDLSVVRHIADRVAVMYLGRIVEIGTANQVFEAPEHPYTQALLSAIPLPDPVKERSRRRILLTGDLPSPANPPSGCRFRTRCPKFANELDDAQRQRCLDESPALTVRDTVVPDHESACHYAAPVKAI
>NZ_LT827010|2333775:2384758|2374555_2375059_-|WP_014689180.1|tail|DBSCAN-SWA
MTWLLAQLPQTMARDPFLAGFVTGCQQVADSVRAQIDDLEHELDVDLASPEMLAYLGSWLAVSLRPATTPAELDDQRRLIRAVGSVIGYRGTCYGLERLLSALTGAHVTIGDPGGVALPGEPDRPGGDVRIEMSGTGRCDVAQVHAAIREELPVGVGYRLVVAGREQ
>NZ_LT827010|2333775:2384758|2333775_2334945_+|WP_080127769.1|transposase|DBSCAN-SWA
MRMVYGDDSVRSPQETRVSAFVDEMFGDLGRADQRRWARIYLRGMLTARGKKTVQEIARSVGAESFVARGLRQFINFSPWDWGGPRRRLAEMLWDAAPGQALTVAVSAIPKRGSQSVGVQRRFVVAAGRTVNCQLVVSLFLATGRQLVPVDWELVLGPEWGADRARRARARIPDSVEARPVWRHVLDVVRRSARFRAGLPLVADLSELDEVWPLVVALAGRRELVIAVSPGQRIPACRAGRPGDGTSPTVGELLQAAAAGRARHSVTVPDPDGTPRTVAVQSVALRGGRGADLWLLGEWSPESRRFTRYWLTNRADRPGTTLELGRYADRTAGTLAELRRDFGVLDYEGRSFPGWHHHMTMVSAAYTLQLIDVCSAVLQAAGAVFPGTI
>NZ_LT827010|2333775:2384758|2373828_2374062_-|WP_014689178.1|DBSCAN-SWA
MIGMTADEHAARAAELIDEAERLYQICLVDYHTNINEDDHSEEPYVPGADLAMLTATTQLAQVHATLALRGPAAANG
>NZ_LT827010|2333775:2384758|2348965_2349172_-|WP_043511156.1|DBSCAN-SWA
MVDHGTSTSGSRSARSPSWTGVFVPTTGQRPPAAAEPRRRRRSRPDEVADECGGVPDVIDFEKEFDRR
>NZ_LT827010|2333775:2384758|2362908_2363550_-|WP_014689167.1|DBSCAN-SWA
MRIVIAEDSVLLRAGLTKLLTDGGFDVVEAVADAVELLRAVAAHRPDVALVDVRMPPSHTDEGIRAALVIHHEFPAVAVVVLSQFVEERYATDLLSVRTSGVGYLLKDRVAHVPDFLAAMRRVAAGGTALDPEVVAQLLVRHRADPLQRLTPRESEVLRLMAEGRSNNGIAGELRVSHSAVEKYIGSIFTKLDLPHTDSDHRRVLAVLRYLRP
>NZ_LT827010|2333775:2384758|2383168_2384758_-|WP_014689191.1|tail|DBSCAN-SWA
MAVGGAPGVYIEEQVSGSMPLQGVGTSVAAFVGFTERYDAAQGDDSDPEGIKPQLVTSWPQYERIYGGFAPGIMLPHAVHGFFANGGSACYVVRIPVRSVRPARRSLPATGREEADSLVIEAREPGAPVEVTVVHEPPAVEGEAPQEFSLTVDRAGGQTETYPRLTFGTGKGTSAAVRTINERSTLIRVEARTVAGLSPAERIPAAGTYLVEPAPSAATATTGDLAGSETERTGYHGLAIAEEVSIVAIPDLVTVVRRPDGGIDQTAYLEAQARLLDWCEQRRTTMAVLDLPPGLTAQQALEWRDRLKHDTAFGAAYYPHLIVANPNARPGSTAADRYLRIPPSGHVAGVWARTDGARGVWKAPANEALRGVARLETEVTTGEQDLLNPSQINCLRSFGANGMRVWGARTLASQDQAWRYINVRRLFIYVEETIRQGTQWCVFEPNDEALWGRAKRTIGAFLHQLWMRGALVGASPEQAFFVTCDETNNPPGSVDNGLLVVDVGLAPVKPAEYVIFRISQWQGGVATAE
>NZ_LT827010|2333775:2384758|2346793_2347915_-|WP_014689155.1|DBSCAN-SWA
MNTAGMLDLDDFRRACQGVLDAARWSYLAGGAGHDDAVRENEAALRRLRLRPRPLNGVADPDLTVDVLGFPAAMPVLLAPTSPLRLFHPDAELAVSRAARRAGVLPIVSNDSHHSLTEIAKQGPCWFQLYCYGSRADVVRTIRLAESVDARALVVTIDNSHPSRRVAMLRSGFATPPEVEFGIHRESGFSDGAVPPDTRLPRWPLTWELLDLIRSQTRLPVVVKGVLHPADAALLTDRGVAGLIVSNHGGRQLNDSIAAIDALPGVVAAAAGRLPVLLDGGIRTGGDVVKALAAGAAAVCLGRPYVWGLTLDGEDGVLAVLELLRAELLDVARQTGLRALRAVPADLVAPPPPSFTGRGGGPHDPAHQGALRA
>NZ_LT827010|2333775:2384758|2340005_2341184_+|WP_099343731.1|DBSCAN-SWA
MALACGVGVANVYFPQAITPLLARDLHISESTATTVATMAQLGYAAGIFLLVPLGDRLPRRRLIATLFGVVAAGLFLAGISSSVPPLLAFCAIVGAATVVPQILIPMAADLAGPTSAAGTVGILQGGLLGGVLLARTFGGTLGQLLGWRAPYLIAAALAVLLAIALVVALPATAPSSTERYPALLATSLRLLRTQPALRWSCLYQFLLFGAFTAAWTSIALHLTGPAFGYGTSVVGLVALVGAASVFAVPVAGRQIDRRGPDVISVLCFGGLLLAAAVLLTGTWHGVPGLIGLTAGMLLLDVSVQTSQVANQARIFALVPGARSRLNSVYMTAVFLGGTCGSWAGARIYLHFGWGAVAALVAVAGVAALAGHLLRLRITAPAGRRESAEAAA
>NZ_LT827010|2333775:2384758|2371882_2373292_-|WP_014689176.1|DBSCAN-SWA
MSERLARRYARLLRCYPPGPRRAEMLGTLLECAPPGRDRPTAVDIVNLTRYGLRARLGRPASTSVVLLSLLVALVCGLLGAATGARLGWMLQKPLPSGAQARELTTAAFPGLPVLGGGDAPPFVPASGADGGEVYGFAEYWVRNTPETRDVPAYTRGVRDRLAGAGWQIRDDVTAEQDDEQASWSAGFTATRDDLILNYSAYYVKDHPWYDSDGSAGFQLSRTTPPWPARFAVPAGLLAACAGWLLFGWASRRSEGRPARTRGAVLLVWSAMLVVAASLYFICLWYTQPGPLEGRPLWTTLDQLSGAPTTLVFGLGMLALVTAALPARHRILAAAALVLFMVVAMNGRPSWTRPGCTPSGPPAALPAAEVATGLTARVYVTGDASAEQRNIAQAAIWHVPSVRSTAWSGDVTDQDYRDAYCGGGRITGASRATLPGFWLVELSSPGGFDGLVAEVGGLPGVAAVRHSAP
>NZ_LT827010|2333775:2384758|2382366_2382723_-|WP_080127771.1|DBSCAN-SWA
MSLHTEFPFTLPKGYVDEEGTLHRTGVMRLATARDEIEPLRDPRVRENESYATVIVLARVVTELGTLPRINTGVIERLFASDFGYLQDFYQLINFGDPAALDALEPGAPFPRVSVEVV
>NZ_LT827010|2333775:2384758|2347911_2348808_-|WP_155123469.1|DBSCAN-SWA
MTTHSDDIVTAYLAPAESADMARRARREITGTGAPGDCFRRAGRHAGILPARLREALARLRAGSLDAVVAHGLPADPTDADAPPLLGLTWLGMLTRQLGHEFGYPAEQNGTLVHHVRPRPDRAATQSNASSAVDLRLHTEIAFHDVRPDFVLLYGVRSPEPRPATRLVRVADAVRNCSPETVQRLRRPQFRINAPDSFSPGQAVAENVAPMGGTLRQPTIRWHSSITGVDDVDQCAIAEFQAAADREEHLVRLAPGSFLAFSNSRCLHGRDAFEAHYDGHDRWLLRTYVRHDLTRGRG
>NZ_LT827010|2333775:2384758|2364793_2366038_+|WP_099343732.1|DBSCAN-SWA
MLEPTTNTDTTAAVRPLRRRTLLTATLAAGIGLAAGIGPAVPAAARRRSTGGYVLPAPTGTAGVGTVALHLRDTSRIDPWVPGRRAREIMIQIWYPARDLRGHLPEPWLSPGAVPHFAETFGLPADRILSTRTHGRTGAPVLRRTGGHPVLLYSPGLGGDRGTGTVLVEELAAHGYLVVTIDHTHDASEVEFPGGRVEVAALPPDLTDEVVVQAAAVRAADTRFVLDQLAVLDAGGHPDVGRRRLPDGLRGAFDLHRIGMFGHSLGGSTAAAVMHDDRRVKAGVNLDGTFVGPAAAGGSTRPFLLVSSDHGPGAEDPTWNTFWAAHRGWKRQLRLRDSVHGSFNDGIALYPQAGTEIGLTPQQLADLVGTLDPARSIGIQRTYLRAFFDRHLRGRDGRLLAAPDPRYPEIDFVR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080127769.1|2333775_2334945_+|transposase	transposase	NA	NA	NA	NA
WP_014689144.1|2335032_2336208_+	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_014689145.1|2336237_2337305_+	alcohol dehydrogenase catalytic domain-containing protein	NA	NA	NA	NA
WP_014689146.1|2337363_2338776_+	trehalose-6-phosphate synthase	NA	NA	NA	NA
WP_014689147.1|2338781_2339288_+	flavin reductase family protein	NA	NA	NA	NA
WP_080128203.1|2339320_2340007_-	ABATE domain-containing protein	NA	NA	NA	NA
WP_099343731.1|2340005_2341184_+	MFS transporter	NA	NA	NA	NA
WP_014689150.1|2341242_2342052_+	SDR family NAD(P)-dependent oxidoreductase	W8CYX9	Bacillus_phage	7.7e-09	48.7
WP_014689151.1|2342067_2343309_-	MFS transporter	NA	NA	NA	NA
WP_014689152.1|2343305_2344634_-	hypothetical protein	NA	NA	NA	NA
WP_014689153.1|2344630_2345473_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014689154.1|2345492_2346695_-	cytochrome P450	I6XNL0	Cotesia_sesamiae_Mombasa_bracovirus	9.1e-06	43.1
WP_014689155.1|2346793_2347915_-	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_155123469.1|2347911_2348808_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_043511156.1|2348965_2349172_-	hypothetical protein	NA	NA	NA	NA
WP_014689157.1|2349678_2350677_+	ABC transporter permease	NA	NA	NA	NA
WP_014689158.1|2350688_2351597_+	ABC transporter permease	NA	NA	NA	NA
WP_172898871.1|2351608_2353735_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-15	30.2
WP_014689160.1|2353818_2355531_+	ABC transporter family substrate-binding protein	NA	NA	NA	NA
WP_014689161.1|2355756_2357601_+	PAS domain-containing hybrid sensor histidine kinase/response regulator	NA	NA	NA	NA
WP_014689162.1|2357609_2358221_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_043511159.1|2358340_2359918_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-05	29.0
WP_014689164.1|2360075_2361260_-	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	1.1e-27	28.5
WP_014689165.1|2361285_2361729_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_014689166.1|2361741_2362887_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_014689167.1|2362908_2363550_-	response regulator transcription factor	NA	NA	NA	NA
WP_014689168.1|2363537_2364662_-	two-component sensor histidine kinase	NA	NA	NA	NA
WP_099343732.1|2364793_2366038_+	hydrolase	NA	NA	NA	NA
WP_014689170.1|2366187_2366817_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_099343733.1|2366817_2367732_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_014689172.1|2367786_2368224_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_014689173.1|2368248_2369637_-	DUF2079 domain-containing protein	NA	NA	NA	NA
WP_043513908.1|2369732_2370413_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.4e-26	30.6
WP_014689175.1|2370409_2371864_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_014689176.1|2371882_2373292_-	hypothetical protein	NA	NA	NA	NA
WP_043511166.1|2373288_2373636_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014689178.1|2373828_2374062_-	hypothetical protein	NA	NA	NA	NA
WP_014689179.1|2374143_2374494_-	hypothetical protein	NA	NA	NA	NA
WP_014689180.1|2374555_2375059_-|tail	phage tail protein	NA	NA	NA	NA
WP_014689181.1|2375055_2376999_-|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_014689182.1|2376995_2377394_-	GPW/gp25 family protein	D5LGZ4	Escherichia_phage	3.5e-07	48.8
WP_014689183.1|2377390_2377786_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_014689184.1|2377806_2379447_-	VgrG-related protein	NA	NA	NA	NA
WP_014689185.1|2379436_2380108_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_014689186.1|2380130_2380940_-	hypothetical protein	NA	NA	NA	NA
WP_099344031.1|2381739_2382207_-|tail	phage tail protein	NA	NA	NA	NA
WP_080127771.1|2382366_2382723_-	hypothetical protein	NA	NA	NA	NA
WP_014689190.1|2382719_2383154_-|tail	phage tail protein	NA	NA	NA	NA
WP_014689191.1|2383168_2384758_-|tail	phage tail sheath family protein	J9PVC2	Bacillus_phage	1.3e-52	30.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_LT827010|6501598:6545938|DBSCAN-SWA
CGTGGACGCCGAGCTGGTCGGCCGGCTGGTCGAGCAGGCTCGGGCTGCGGGCCTGCAGCTGACTGGTGAAGGCGGCCTGCTGCAACAGCTAACGAAGCGGGTGATCGAAGCCGCGCTGGACGGCGAGATCACTGACCACCTCGGTTATGAGAAACACGACCCGGTCGGCAAGGACGGCGGGAACTCGCGCAACGGCACCCGTGCCAAGACCGTGCTCACCGACGTCGGCCCGGTCGAGATCACCGTGCCGCGGGATCGAGACGGCTCATTCGAGCCGCAGATCGTCAAGAAACGGCAGCGGCGGCTGACCGGCGTCGAGGACATGGTCCTGTCGCTGTCCGCCAAAGGCCTGACCACCGGAGAAATCAGCGCTCACCTGGCCGAGGTCTATGGCGCCGACGTCTCTCGCCAGACGATCTCCACGATCACCGACAAGGTCATGGACGGCATGGCCGAGTGGCAGAACCGGCCCCTCGACCGGGTCTATCCGGTCGTGTTCCTGGACGCGATCAACGCCAAGATCCGCGATGGGAAGGTCGCCAACCGGCCCATCTACGTCGCTCTGGCGGTCACTGTCGAGGGCACCCGCGACATCCTCGGGCTGTGGGCCGGCGACGGCGGTGAGGGCGCAAAGTTCTGGTTCAGCGTGTGCACCGAGCTCAAGAATCGTGGCGTCGAGGACGTGCTGATGGCCGTCTGCGACGGCTTGACCGGCCTGCCTGACGCGATCAACACCGTCTGGCCCAGGACTGTGGTCCAGACTTGCGTGGTGCACCTGCTGCGCAACTCGTTCAAGTACGCCGGCCGCCAGCATTACGACGCGATCGCCAAGGCGCTGAGGCCCGTCTACACCGCACCGACCGAGGCCGCTGCCGAGCATCGGTTTTTGGAGTTCGCCGAGGCCTGGGGCGGGCGATACCCGGCCATCGTCCGGCTCTGGGAGAACGCCTGGGCCGAGTTCGTGCCGTTCCTGGCGTTCGACGCCGAGATCCGCAAGGTTGTCTGCTCGACGAACGCCATCGAGAGCGTGAACGCCCGGATCCGCCGGGCGGTCCGGGCCCGCGGGCACTTCCCGAATGAGCAGGCCGCCCTGAAATGCGTCTACCTCGCCGTGATGTCCCTCGACCCGACCGGCACCGGCCGCCGCCGCTGGGCGATCCGCTGGAAACCCGCCCTCAACGCCTTCGACCTCGCCTTCGAAGGACGACTCACCGCAGGCCGCAACTGACCTTCAACAACATCGAGTTACACCGTTTTCTTGACAGTCCCGAAGGTTGGCCAGGCAGTGAGGTACTGGCTCAACTGACGGATCTGTCGGAGCGAAGTATCCAAGAGGCCCTGCGGCGAGTGGCGCAAAAGTGGATTGATCTGCGAGTCGTTCTAGGCAAGGACCGGCACGGCCAGCCGTTCTATTCGGTGCCTGGCAGGCGGGTTACCTTCCGCTTTCCCAAGTTTGGGAAGGTACCTGAAGGTGCGACAGATCCGGGGGCTAAAGGTGCGATGGATCCGGGAGCTTACGACGACGAAGGTGCGACAAATCCGGGGGCTACTGGCGAGTTAGGTGCGACAGATCCGTCAGCAAGGTGCGACAGATCCGTGCCTAAGGTGCGACAGATCCGGGGGCCTTCTCCTCAAAGAACCGCTCATAACTTCAACCACTCACAGTCTCTCTCTCCGCGCGCGAACCAAGGTCCGCCTTCCCTGGCGCCCGAAGAAGATCGAGAAAGAGATCATCGCCTAGATCATCAAGAAGCTAACCCGGTCAACAACTGGCTCGCTGCCGCCGGCGCTCCCGACGAAAAACTCACCGAGATCCGGGATGAACTCGTTCGCCGCTGTCAACCTCGGTCTCTCGCCTGGTGGCGCACCGTTCACGGCAACGGCGACCTGCGACAACTTGTCGCAGAGGTGCTGGCGAACCCCAACAGCGGGTACCTGCAGCCTCGGTCGCCAGCGGATCAGCGCGTTGCGGAGAACCAGGCGCTATATGAGAAGTTCCGGCGGCAACCGCGCCGACCGCGAAAGAACACGGCGCCCGAAGATGTCAAGGCGTACTGCGACATCAGCAAGCCCTGAATCCCTTGGTCCCAACCCTGCTGAGTTAGCACATGGAGGAATGATGACCTTCCGTGACAAGTCCGTGATCCGACACCAATCGGGTAGCCGCATCGATACGCTACGAAGTGCCGGGAGTTCAGCAAACCCCGTCCGGAAGGTGCCAGACTCGACGACTTCGACCCGCGCAGATGTGCGGAATCCATCACCTGGCGAGGGTCTACCCCCTACCCCCATGACGGCATACGTTGCGGCGATGAGCACCGCGACCGACATCGCTGCCGCCCTACGCGAACAAGCACAGGCGCAGATCCCATACGGGCTAAGCAGCAACCTCACCGATGTCCAGTACGACGCAGCCCGGTTTGCTGTTGCCTCCTTCGGCGCGCTGAGCGCCATGGACCTGGAGGCGCTGGTCCGAGGGCAGGGCCCCTGGACGGCTACACCCACCGGCAAGGCCATCGACATCACAGTCATTCGCGACACCGTCCGCGCCCAGCAGGAGATCCCGGAGGGCAACGTCTCCGGCTATCCCCAGTCCCTGCGCCAGGCGATGCTGCGCCCTGCAGACCAGCGTCCGCCGAGAGCCGCCACGCCCGACTCTCCCGAAGAGATCGAGGCGTTCATCGCCGACGTTAAGGCGAGAATGTGAGGCGTTGATTGCCCGCAGCCAAGTTCCGACTGTTCGGGTTCATGAACGCAGTCCGCGAATGGACCCGCCATGACCCACCAGCTGGCGACCTTCTGGTTAAGGTCGCCAGCTTCGGCGCCGAACTGGAGTCCAACCCGCAGTCCGGCAATATCAGCCAGGAACATCCGGGGTACTACACCGCCGTATTACCGGCACCGAGCACAACGGGCGCATCGTCGCCGTCACCTTTACCATCGAAGGACGACCGACCAACGACTACGCCGGTGAAGTGCACTGCCAGGACATCGGCTGCATCACCCACCCGCAGGATGCGCTGTTCGAGCAGTGGCCGGCCGCACCTCACCACCACCCCGGCGCGTCGTTTACGACTCAGGCCGGCGAAGCTACGAACTAGCGCCGAGCTGCACGACCTGGTCCAACAGTTGCTCGATCAACTGGTGGTCGCCGGTATCCTCGACCGGCATAGCACGTGGTCGGCGCGGCAGCACTCGCCCCGGGCGCCTTGAGGTTGGCACATCCGTACGAGTGGCGGACTTACCCCGCCGACAGTACCGGCCGATACCGTCATCCCATGAATGAGCCGCCGCATGAGGGCCCAGACGACTGGTACTTCGACGAGAAGCTCCAACGGTGGCTGCGCCACTCCGGCAGGGCCTACTGGCGGCAGTTCCTGGCTGAACGCCGGGAACGCGCGGCCACCTGCGAGCTGCAGACGGGACGGGAATTCCAGCAGCAGGCGTTCTCGAAACGTATCGATCTTGTTCAAGATGACGACAGTTCCCTCCGCCCCGCTAAGGTGGTTGGCATGGACTCCGACGCCCCCATCCCCGCTGACGAGACCGGCCGCCCGCCGCGCGCGTCCGAGCGGCTCATGGCGCTGCTTGGCAGGTCAGCGCCAGCACCGATGACGCCCGAACAGCGGGCCGGCTATCAGGCGCGTATGGATCGCGCGGACGCGGACCTGCGGGAAATCATCGAGCGTCGCAACACGCCGTCGGCCGCGTGACGCACTCTCCCCGCGTCCTGGACGCGTCCGCGCTGATTGCGATGTTCGGCGGGCATCCGGACCTCATGGAGATGCTCGATGACGCCGAGCGCGGCAATGTGTTCCTGCTACTGCCGACGGTGGCGGTCGCGGAGGCCGAAGCGGCGCTGAACGTGGGACTCGCCTTGTGGACCCCGTTCCTGATGTCCCGGGGCGTCACCACGCTTGATCTGACCATGCATACCGCGGTGGAGGCCGCGCGACTGGCTGATCCGCAGTTGCCCGGCGCGGTGGCGGGCCCGCTGATGGCCGGTCAGGTGGCGTTCGAGGCGCAGGCACTTAACGCGGTGGTCGTCACTCAGATGCCGAGCATGTATGCCGGCTACGAGGTGGCAATCATGCCGGTGGAAGCGTAGCCAGGTGGAGGCTTCCGTGGCGGACCGATCAGGAAGTGTCAGTGCCGTCATCCGACCGCGCTTTCACGATCGAAGCCAGTCGCTCCGGGACTCGCGCTTACGTTGCTAATTCTGTAGAGCGCCGGGCTACCTGACTGTCAGGTATCAGATTGCCTGCATAGTCGATGTCGTTGCACTCGCGCAACTCCGCCCCTATGTTGGCACCGTGGCTGGTCCTGAGTTTGAAGGTCAAGAGGAACGACGCGAGGCCAACAGGCCGCGAGACGACTGGCCTGCGATTGTTGAAGCAGTCAAGACGCCCCTCGGCTTCTTTGCGCTGGTCGTGCTCGCCGTTGAAGGCATCCTCGCTGTGGGGGTAGGGCTCACGAGCGGGCCTAACCAGACTTATCTGGTTCTCGGCATGATCGGCCTCGTAGCGTCGCTGATCCTACTCGTCACCGGAATGGCGGTATGGCGGCCCGAATCGCTGTACGGGAAAACGCCGGAGATAGTCGTTTCGATAGCGAAAGCGCCCGCCGGATCAGGATCGCCTGATACTCAGGACGGCGGCGTGGCAGAAGTCGTCGAGAATCCGAAATTCTTGATAGCCGGCTCAGAAGCCGCACCATGGGACCGTTTTCTCGAAGAAGACCGCGGAATTATCACTGCGGCATTTCCGGGCTCCACTGTTTCGGTTGAGCCCGCAGAAACCGCAGCAGGCTTCAGTCAGGCACTCTTGACGTTAGGGGCACACGCTCAAGTTTGGCAGCTCTCTGCCCAAGTTGAGGGAAGCGGAAGCATACAGATCGGAAGCGATTCGCTTCCGCCGCGCGGACTTGGCGAGGTCGTACGTCAGTCACGACCGAAACTCGTCGTTCTAGCAGCATGCGCCTCAGCATCAGTCGCTGCAGAGATCGCCCCGTCGGCCGCCACGGGAACTCTTGATAGTGATGCTTGGAAACGATGGAGTACTATCTTCTACACACTGCTCGCGACCGGCGTGCCACTGAGCCGGGCATTCGCAATTACTCAAGCCGTAGATGGACTTCCAGTAGCCATGATCTTACGGCGAGATATGATATTCGCTGGGAGAGATCAGCGTTCGCTCCGGGCTGGAAAGTGAAGACAACGAGAATGGCGCACGCTGAACTGAAAGCGAAGGCAAGCGATTCACTCATTTACTGCCAGCCGTGAACGGCGGCCAGGAACGGCCGTTACTTTGCAAATCGCTCACCAGTACAACGCGGCTTCGCGGTGCGCGGTCATTAGTGCGTGGCGAGGGAAGCGACGGAAGGCAGCTCTGTCGGGGGCGCTACGAACCGGCAAGAAATACCGCGTGATCCTGGGCGACCCGGTAGGCCAGCATCGGCGGGTGCTGGTCGTACCAGCTTTCCGCATACGTCGCCACCCGCTTGCCCAACCTTCGTCCGAGCAGCCGGCGACTCTGCAAAATTTGTTCAGACGCTGCTGGTCCCGCAGTTGGTGGAGGTCTGCATCGCTGACGCACCAGTAACTCGCAAGAGCATGCCACTCGTCAAGGACGGTAACTTTTGCCGGTCCAGTAGTAGCGAGTATGCGTTACCGCGCCGTCGGCGCAAGGTGGACTACAGTCGTTGATGCTTTGGTCAATGGCGTACGAGCCGTCCCCGGCATCGATGAGATTGCTTGAGAAGAAGTACGGATCTTCCGGCGAGGGGCCGAGTTCGGCGAAGCCGCGGCGGACTGGATGAAGCACCACCACCCCTTTGTCCCCGCCCATACTGAAAATGAGGAAAACATTACCGGTACGGTCCCGGCCCGCGATCGTGAGTTCAGTCCACGTGTCCAACTCTTGCTGCCAACGTACCTTCCCGGTCCGGTCGGTGACGACGACGCCAGCGATCGGCTCATCTCCGCTTTCGTCCAACGTGCTAAGCAATGTGACAGGCCCCCAGGACTTGTGATTGACGGCGACGTGTCCGGTCACCCGACACCCGGGTAAGCATGCGCCGTGCCGCTGCAGGTCCTGCCAGGTCGGCGTGGCTAGCGTCGGTTGAGTCTGTTCAGCGGCTGCAACGATGTCGGCCTGGCGGACGGCGCCGCCGGCGATGAGCAAGCACACTGCCGCGCCGGCCGACCAACGCCAGGCCGCAGGCCACTCCTCCGGCGGCCAGGCGCGACGGCGGGAACCGGTCACATTCGTCGCAGGTACGTGCAGTTGATGGAGCAGGCGTACGTGCCGGAACCGATGGGTGCTTCCAGTCTGTCGCAGCACGCCGGCGTCTCGGGCCTGCTCGAGCAGGCGCAGGAACCGCCATGGCAGCCGGCCGGTCCCAGCCAGCCACAGATGTGCCGTGCGGTATTGCAACCATGCCGACGTACGTACGACTGCGACCAGTACCGGCAGCATGATCAGCAGGACCGCGCAGACGAACACGAGTGCGGGCCGATGCGGGTGCTGACCGACCAGGACGGCCGCCAATGTGCCGGCAACAGCAGCCGGCACGGCCAGCAGCAGCCCTAACACTGTGGCGTCGGTGTGTAGTGCCTGTCGGGGGCCCGCCATCCGGCCATGGTCGATGGGGGCCAAGACCCAATGCAGCACACCGACCAGCAATCCTGTCAAAGCGCCGACGAACACGAACGGTGCCATGTCCGCCAACGCCGGCAACGCCGGCACCGGAAGGTCGCCTGTACTGATCCCCGCCGCCCACCACACCGGCCAGGAAAGTGCAGGGAACAGTAACGTCATAACGGTCACGGCAATCGCTCCCGCAATTGCGCCCAGACCGACACGTGGCACGATGACCGGAGCTGCGTCACCGAGCCGAGGGGCGACCCGGCGCGGAGTTCGGTAGCCGGGTCCGATGCTCACCAACGTTTCTCCAAGCAGCCGCAGAGCCAAGGCCACCACCGCGGCCTGGACCGCACCCCACCACAGAAACGGATCTACTGCGGTCAGCAGCGCCGCCACGGTCACCGCAACCAGCCAGCTCAGCATCACGCGGCGGCGCGACGCGCGATGCCGCCTGTGACGTGATCGCACACGAGGGCGTCGGCCGGCAATGATGCCGCTCACGGCCGCGGCGACAGCAAACCCGGCCAGCACGGCGAACTGATAGACCCGCCCGGGGCTCACCTGTCCCTCCACCGCGCCGGCCACGAACACCGCGCCTCCGCAGGTGAAAGCTAGCGCGGTGCCCAGCCACCTTTCCCGACGCCGATCCCAGTCGGTGTAGCGAAGATCGGCCCACGAGGGCGACAACAACCAGACCGTGGCGAAAACGACGAAGAGCAGCCCCGTGAGATCCACGACGAGCGTACGCGCGCCATACACCGCGGCGACCCCGCCAACGGCAGCAGCCAGAAGGCTTACGGCACCTGCCCCGGCAACGAGTGCCGGCACCGGAATGGCCCGCATCCAGTGCGGCTTCTCGACGTACCGGCCGCCTGCGGTAGGCCGCGGAGGAAGAGTGATAGCCCCCACGGTCACGGCCACGAAGACCCCGGCCAGGGTGGCGAACAAGGAGGTGCAGGCCACCTGCCACTTGCCGCCGAGCACCACCGCAAAACTCACCGCACCTAGCAGGCCGAGTGTCATGGAAATCGGCGCAGCCGCCGCTACGGCAGGTACAACGTGGGGGGTTTGCCACCAGCTGAGGTCACCCGTCCGGCCCGTACGGACTATCGCGGCCAGCGTTCGCAGATGCCGATGCACTGTGGCCACTCGCCGGGGCGAGATGACGCCCCCGCTGTCTGCTGCGATGCTGCGGGCAGCCTGATCAACGTATTGGCCGAGCAAGGTTCGCTCCAGCGCAGCACGGTCGGGCAGTCGGGCACGGTCAAGGAGCTCGGCGGGATTGGCCGCTGCAGTGTCGTACAGGGCACGGGCCATGGTCACGAACAGCGGAGTCCGCAATACCAGGGCAAGCGGGTCCCGCTCAGTCACCCGTGCCTGCACGTCGCGCCAGCGGGCCGCGGTTGTTGGCGGCCCGGCCTCCTGCAGGAAGGTGAAGGCGGTCGCCAAAGGCACCGGCTGCAATCGCAGCACAGCAGCCGCTGTCAACACGTCGCTGGCGGTAACCTCGGCGGTGTATTCGTCCGCGCGACTGGTGATTACCAGAAGCTGCGGGGCCGACAGGCTCTGGTTGATTTCGTGTAAGGCTTGCCGACGCGCCTGTGGCAGCAGTTCGTCGAACCCGTCCAGAATCACCAACAGCCGACCAGCCACCAGCAGCGTCCTCGCCACAGTTCGCGCCTGCGGCACCGCCGGATGATCGTCGGCGATTTGCTGCACTAGCCATTGCGGCAACGGCTGGCGGGTGACGTTCCATGCCGCCAGGGACAGCAACACGGGTACGGGCTGGCCGGATTGCCAGGCGTCGGCTCGCAGCACCGCCAGCCTGCGCGCGGCGACAGTCTTTCCGCAGCCAGCCGGGCCGATCAGCACCATTCGGCCGGAAGGTATGGCCGAAAAAAGGGTGTCGATTTGCGACAGGTTGCCGGTTAGCGGCAGCGGGGTGCCATCACCGTCTCCCGCACGGATCACCTGCCAATGATCGGTGATCGCCGCATCCGCTGGCCTTAGTTGCACCGGTATCGGCCAAGGATCATTCAGCCGTTGCCGACGCTCCTCCTCCTGCAATTGGCGGCGCACGTCGGCCACCAGCGCAGCTTCAAGCTCCGCTCCATCCGACGGCGTGACATCGGGCTTGAGCAGTTTCATACCCGCCACAGTGGAGCCGAAGGCAACCAACGCACTGATCACGCCCCAGAGCGTGCTGGCGGTGTTCAAGGTGGCTCGTACGCTGACCACCGTCGTCAAGACGACGGTGAACACGACCACGCTGGAAATCACCCAGATACGCCGTCGACGCGTCATGGTGTCATCATGCCTTTGGCCGCTACCGTCCGCATCCGCCGGACAACGCAGCTTGTCCGGCCGACCACCGGCCTTCGACCCGGCGATCTACCAGCAGCGCCACGCCGTGGAGTGCGGCATCAACCGCTTCAAACGCCACCGCGCAGTCGCCACCAGCTTCGACAAACTCGCCGTGTGCTACGAAGCAACCGTGACCACCGCCGCGATCAACGAATGGCTATGCCTTCGATACACGCCCTAGCGCGATATCTGCGCCATTCAAGATTATTAACGCAGTTCGTGCCAGAGCCGACGTTCGACACCATTTCGCCAGCGCCGCTCGTCGCAATACTCGTGAGAACCGGCACCTCTCGCGGACCTTGACCGCCGTCGGCACCGACGGCGGTCAAGGAGTCCGCTGACGCTGCGTACAAGCGATCACGAAGCGACCCTTTCCGCGTGATTTGTCTGCAATCCAGCTCTTACAGGTCAATGACGCGCTGGGAGACAGCGGCCCGGATGGCGTCGGGTTCAACCACAACGAGACCGCGCAACGGGATCGTCCACTCTCCCAGCGCCAGTGCGGCCGCCATGACCTGCTTCGCGCGGATGGGCCGTCGCCCGCGGGCCAGGCCTACCGCAAGATCGGTCATGGCTCCGGCCTTCGCCCACGGGCTGGTTATCTCCTCGACGATCCGCAGCGCATCGTCGGGGCGTCCGCCGTCCCGCGCCATGACAGCGACTATGCGGGCGAGAGCTTGGTCGCGGACGTCGTCACCGCCCGGTCCCGAGGTGAACACGTTCCAGCGTTGCGTGAACGCACGCTCCGGCGCCAACGAGCGGGCAAAATGCAGCGCGGCATCTAGGTGGCCGTGCTCGGCGAGCGCCTCGGCCAAGTAGACCTCCATCGCCGGGGTGTGCTCGGCGTCGTCTTGGAGCAGCCGAGCGGCCTCCTCCGGCCGGTCCAACCGCAGCAATGCGTCGATGCCTAGAACGACCGGTTCGGGAAGCATCCACGAACCGTCGCAGCCGACGGCGGCCTCCGTGGCAGCGGCGATCATCCGCGTGACGCTCGGGGCGTCGCCGACCGCGCTCCAAGCGGTGATCAGCCGGCTGAAGGCGCAGCACCGTTCCCATGGATCCACCAGTGCCTCGGCGATCTGCTCTGCTCGGCGGATATAGCGGACAGCGGCATCGGGGGTCAGCGTGCCGCCGGCAATCGTCTGCACCGCCAGCTCCGCGTGAAAGACGGCCCGCTGCCAGGCGAGTCGCAGCTGCTGCTCGACGGCCGGGATCCGATCGGCATGCCCGGCCGCTAGGAAGACGGTGGCGATGCATGCCGCCGTCTCGGAGTGCTCGACGCTTTCTCCCGTGGGCAGGATTCTCAGTGCGTGTATGGCAAGTAGATCGGCATGGTCGGCGTCCCGAACCTCGAGGTAGCCCTGAGCTACGACGGCGAGGGCGTGGGCACGCTCGCCAGGCTCCGCGGCCCGGCCAGCCAGCCGGGAGGCCAGCCGTAGGCGCTGGCTCGCCACGAGCGCTGCGGTGACCTCCTGCAGGATGTCACCCTGCAGCTCCTCGGCGAGCCGGGCTGCGAGCTCTCCCGTCCCATCCTCATCACTCGCCTCTGTGTCGGCGCGCGGCTTTCCGGTGGCAAGCCGGGCGAGCTGGCTGAGCGCTTCCCTGCGAGTCTCTTTGTCACCGATGCGCCGGATCCGCTTCTCGGCCCCCTCGAGATCACCCAACTCCGCCTCGGCGCACGCAACTAACGCCAGGTCCTCGTCCGCCCGCTCCGGATCGGTGGTCTGGCGTGACGCGGTGTCGGCGGCCGTGGCCACCCGCAACGCCGCCCTAACGTCACCCACTGTGGCCAGAATCCGCGCGGCCCTTGCAAGTATCACGCCAGCCTCGTCAAGGTCGAGCGGATCGACCTCTGTGGCATCGAAGTCAGGCTCGTCGACGTCGAAATCGGTGCCGGTCAGCCGGCGCTCAACTGCGAACAACGCGGCTCGCCGGGCCACCTGTGGCCGGTTCTGTTCGATGGCGGCCTCGGCGAGTTGAAGGGCGACGTAGGCCTCCTGGACCGGATCATCAAGGAGGTCGACGGCCTGCATGGCGGCACTCTCCCAACCGCCCTCGGCGATCGCGGAGGCGACCGAAACGAGGGCGTCGTCGGGCACGCGTCGCAGGCTCCGCGTCATCAAAGCGTCGTCGGCCATACGGGCAGCCAGGATCGCCAGGTGGGCGTACCCTTTCGGGCCGGTTTCGCTGGCGAGCCGTTCCGCCTCCTCGAGCACGCCCGGGCCACGAGGGTCACCGCGCGACATGAGCCGGGCTCCAACGGCCGCGACCCTGCCCACCTGCTCGGCGGCTGTCGGCAGGGTGCGCGCCAGCGCCAGCGCCCGGTCCGGGCGGTCGGCATCGACGAGCAGGTCGCAGAGGTCGTTGACGGGACTCAGCCGGTGCGCGGCGCGGGCCAGCCGTGCGGCCAGCGCTTCGGCGTCGGCGAATGACCCCGCCTCAACGCAGATCGCCAGCACGGGTCGACCGGCGTCGGCCGGGTCGGCCGTGCGCAACAGGGCTGTTTCGGCCTCCTGGTAGCTCCCAGCCCGGGCTAAACAGCGAGCAAGGGTTGCCAGGATGGTTTCGCTCAGGTGTGGATTCTCCGCGGCTAGTTCCAGCACGCGCCGGTGAAGGGTCGGGCTGATCGGGTGGCCGGCGGCGTCAGCGATCGTCAAATCGGCGAGCCCGCGTACCTGGGCGTCTCGTATCTCGGCGGCCACTTCCTGGGCTTCCGAAATCCGGCCGTCCTCGCACAGCCCCTCGATGACCTGGTAAAACGCAGCTTCACGGACGCCGGGGTGCCGGAACTGCCGGGCGTAGGTCGCGCCGCGTAGCCGGGCATACCGGATCACTACCTCAATGCCGTTCGCGCACTTCTCGGCGGCGAAGCCGATGACGCCGTCAGCTTCGTCCGTTTGCCCGGCGGCGAGCAGGGCGGTGGCCACCGAGTGCAACGCCACCTCGCGCTCCGGGTCCGGCAGGTCCGAGGCCACGTAGGCTGCTATATCCGGCCGGCCGGCATGCAGCAACGCGTCGATCATTGACTGCTGGAGTTCCGTCCGTTGCGGACTCCGTTCCAGGGCGTCGATCAGGTTCAGCCCCCGTCCGGGCTGGCCCAGCAGCGCCCAGACCGCGGGCAACTCCGGCGGCATATGCAGGTTGGGTGACGTCAATTCCCAGCGGATCCTGGCCAGCTGCGCGGCGCTGCGCAAATCGGGATCTCGCTGAAGTTGCCACAAGGCCTGGGCGGAAACGACCTCCGTCAACGCCGGGCCGTCGCCACCCAGTTCGTCTCGCATACGGGCGTGCCGGCTGGTGTCCCGTGCAAGCTCGGTAAGCGGACCCACCTCACCAGCGTCAGCGAGACGCTTGCCGTACCGGGCGAGCAGAAAAAACGGTGTCTCGGCCGGCCATCGCAGGGACCGGTACGCGCGGGCCCAGTCGTCAATCCGTGCGCGATACTGTCTCATCTTGGATGCGCCGAGCACCTCGCTGGCCCCCAGGCGCAGGGAGTCGTGGCTGAACGCGAAACCGGTACCGCCGTCCGGGAACGCAGTGAGCACGAGTGTGCGGCCGGCGCCGTTGACCAGCGTCTCACGCACCTTCTCTGCTTCCGCCCCGCTGAGCTCGGCGACTTCCGCAATGCTGAGGCCTCCCTCCGAGGCGACAGCGAAACCGAGCACATCCGTCGCCAATGACCCCATACCGAGCAGGGTGTCGAGCTCCAGCCGCGCCGCGCGCTGCAGGCGAGCGGCCCGAGCCGAGCCGGACAAACGGCGGACTCGGCAGCTGAGCGCGGGATGGTCTACTACATCGGTCGGCTGATCGAGCTGGTGACGGCTGGCCAGAATGACACGCAGGACCGGAGACGGGTCGGCCGGGAGCAGGCTGAGGATGCTCGGCAGCCGCGTGGCCCGGCTCCGGCTCTGATCCTCGTCGATGCCGTCGACCACCAGGGCCAAGCGCCGGCCCGTCGCGGCCGCGTGCTTCACCGCGCGGTCAAGCAGATCCGTCCGGTCGAGGTGCAGAAGGCTGGGGTTCACCGTCCCGGGGTCGGTCGTTGCCAGATAGGCCTGCAGTTGTGCGCGGAGTACCTGTTCGAACGCGAAACTGTCGTTCCAAGACGCTTGGCCGCCCCGAATGAAGAAGTGCAGCACGTCGACCCGCTCGGGCGGGTGCAACACGAAGAAGCCGAGCAGTGCGGTCTTGCCGGCCCACGGCTCGCCTTCCCACCGCATGTAAGGCTCGTCTCCAAAGCAAAACTCCGCCAACTCAGCCAATTCCTCATCGCGGTCCTCGAGCGTGGCCGGCGTCAGCTCGCGTACGTGCCCGAGCATCGCCTCTGGGCGTACGGCCTCGCCGTCGGCACCGTAGGAGATGAAGTAATAAAAGTTTTGAGTATTGTCGTCGCCCTGCTGGAAGTGGCTGCTTGAGGAAATGTTGCCGTTCATTCGGTGGACGGTCTCATGAAGACGTTCTGCTGATTGTTTGAGCCGATCTGGAACCCGCTGCTGTGGTGCACCGAGACCGTGTAATGATCGCCGTCAGCCCGGGCTTCCTGCACGATGTGCTCGAGTTCGGCCGCCAGGTGAGCATCGATAGACACCGCCTTCAGCACTTGGGCCTGCAGGAGCACGCGAGACGCATCGTCAGCTGGGTCGCGAGCTAGCTCCTCCACTGCCTCGGTGACCTGGCGGCCGCGCCTCGAGGCAACGAGCCGAGCCAGGAGCTGGCGGCCCCAGGCGACGGTCGCGGTGCTGCCACTGTCGACGGCGGCATCCGTGGCCCGCTGTGCCATCGCACCGCCGTACGCAGCGACCGCGGCCGACACGTAGGGCATCACCGCAGCCGACAACTCGTCAAGATCCATACCGTCACCAATCCATCACGCGGCGCCACTGACCCGACTGTATACAGTGCGTCGAGCCGGGATCACTCGTACGACCGGGCGCAGGTATCGGGCGCCCGGCCGCTTCCGGTCCTGGTATTCGCCATGGGCGGTCATCGGTCATGTCCCGGCGGAAGCAGATGCCTACCGGGTCGGCGCGGTTGGCGGTGCGGCGGGCGTCGAGAACTGGCATAAGTTCTTGGCGGGTCGACGGAGAGCCCGTCAACCGTCGCGTCGACCCTATCGAGACTCGCGCTCCGGAGTGCGAGCCGCCGTCGTACCGGCCTGAGGCTTACAGCATGACCCCACCGGCCTGGCCGAACTTCGTCGCGTCCAGGTGCACTGCACTGCCGTTGGCCGCAGCCTTTGCAACGGCGGCGATCACGATCGCGGTAAGCGCTGGGGCGTCTGTGGGTACCTGGTGGCCGACGCTGTCAGCGAGGATCAGTGGGCAACCGAGTTGCCGGGCAAGGATCCGCTGGTAGGTGTCCCACAGGTCGGCATGGACCGGGCTGACGAGGTCAGGCCACAGCCGGGCGTCACCTTGCAGCACTACGGCGGGGACGTCTGGCAGGGTGGCGTTCAAGATCTCTACTTCGCCGGTGAGGAAGTCAATTTCGGTGGCGTCCGGGCCGTCCCCGTCGACGAGCCGGCTGTCTGCGGGGTTGATGCGCTGCCGGGGGATAGATGCGTCAACGAAGACCAGGCCGACAACCCGGTGCGGGTATCGGGCGGCGTACATGCGGGCGATGTTCCCGCCGAACGAATGCCCGACGATCACCGCTGGCTCCGACAGCCCTGCGCTGTCGAGTAGGGCTGCCAGCTCGTCGGCGAACCGGCTGTGCGGTAAGGGCGGATTCGGTGCTGACCGCGGGTCTGCACTGCCGATTCCGGGCCGGGTGTAGGTGAAGGCACGCAGCTGGCCCAGGTGGTCAAGCACTGGCTTCCAGGCCTCGGCGCCGCAGCCGAGCTGAGAGATGAACACGACAAGCGGGTCGGGTCCTTGAGCGCTGTAGGCCGTCACTCGTTCGAGACTAGTACTCCAGCAGGAGATCCGTTTCAGGGTTCCGTGAGTGCTTGGCGGGCGTAGTGGCTGGTCCTGGCGGCGGATTGATGACGGCGGCGATAGATTGACCAGGCAATGACGTCGACGACGCGTCTGCCGGGTTCGATGACCAGAGCGTGGAACAGCCGGCGGAGTTCGTTGACGGTGATCACGATCAGGCCGTCCGGGCTCGTGGTGCTGGCCGTGGTCGCGGCGGCGAGGAATGCGTGGGCGGCGATGACCAGGGTGGTCCAGCGGTGCCAGGCTTTCCAGCGGCGGTGCTGGTGCTGATCCAGTCCGAGTCCGCTTTTGGTTGCTTGGAACGACTCCTCAATGCTCCAGCGTCTTCCGGCGACGGCGACCAGGTGGTGCAGCGCGACGAGTTGCGGTGACCAGCAGCGGTAGAACGCCAGTTCACCGGTGGTCCGGTTGCGGCGAATCAGTAGCCAGTGATGGCCTTGGTGCGGGTCAGCTGCGTGCGGCAGGGTGATGAAAGCCCAGTCGTAGTAGCGGTGGCCTTTCGCGCCGTTGCCGGCCGATATCCGCTGCCATGCGTGTTTCGGTAGTCCGGCGGCGATCTGGTCGGCCCGCTGGACGCCGAGGCCGGTCGGTGCTCGGTGTGAGCAGGCGACCGCGAGGACGTAGCCGAGCTGATGCCGGCGTAGTGCGGTGGCCAGCTGCGGGTCACCGCCGTAAGCTTCGTCGCCGGCGACCCACCGGCATGGCAGCCCGCCAGCTACTGCGGTCTCGATCAAGCGGCGTGCCAGCTCCGGTTTCGTAGCGAACGTGACGGCGCCAGGAACCCCTGCCTCTGCCCGTCGCTGAGGGTCGTCGATCCAGGATTTCGGCAGGTAGAGAGCAACGTCGACCAGGCTGTGCCCGAGTGGGGAAGCGTATGACAGGTGCACCGCGAGCTGGCAGTTCTCGATCTTCCCGGCGGTTCCGGAGTATTGCCGTTGCACGCCGACAGTGTGGGTGCCTTTCTTAAGATCGCCGGTCTCGTCGACCAGCAGCACCCCGTCCGGGTGCCCGAGACGGGCCGCCACGAAGTCGCGCACATCGGCCCGCACCAGGGCGTCGTCCCAACTGGCACGGCTGATCAGATCCTGCATCCCGCCCGGACCGTCGTCGCCGGCGTGCTCGGCAATCGTCCAGCAGTTCTTCGTCGGCAACGGTGCGAGCAGCCCGGCAACGAAGTCACGGACCCGGCGCCGGGGTTCGGGTCGGGCGAAACGTGCCTCGATCGTGTTCATCAGCTCGCTGAACAGCTCAGACCATCGTTGAGCGTCTACTCTGTAGGCGGCAGCCACCGCCGCATCTTGGGTCCACACAACCTTCAAGACTTGGCGGTGGCTGCTTGCTGTCCACGGACAAAACCACACCATCACAGCAGCTCAGAACGGATCTCCTGCTGGAGTACTAGGGTCAGGTTATGGATTCCGACAGCATCGGCGACGTGATTGAGGTCAGCACCGCTACCGGGACTGAGCAGGAGGCGCTTGAGCTTGCGAAGCAAGCTGTGAAGGCGCGGCTTGCTGCCGGGGCGCAAATTAGCGGCCCAGCGAAGTCGGTGTTCTGGCACCTGGGAGAGTTCGGCGTCGGCGAGGAGTGGCGACTGGTGCTGCGAACACATGCCAGCCGGTTTGAGCCGCTTAAGGCCATGCTGGTGGAGCGCCATCCGTGGAAAAACCCGGAGGTACTTGCGCTGCGGGTAGCCGCCGGGTCCAGCGAATACTTGGTCTGGATAACGTCCACCGTCGGCGGGGCTGCCGACTAGCTGCGCGCTTTCCCGAGACAGGCGGCAACCTCTGGCACCTGCCTATGCTTCTGCAGTCGCAGCAAAACACCCATAAGCAATCGTGGCGTCACGATGGACCTGGCGTCAAGTAGCCCATAATGCAAAGTGGCCGGCACCTCAAGCGCGGGCCACTTTGCTCTTCCTATCAAACTTCTAGACTCGCAGCTTCGCGATTCGCTGCAGCGATTGCTTGCGCTCGCCACCAGATCGCCTTTTCTACTTCTGGTTCATCCTCGACAGCTTCCACCCTTACCCTGCGGCCCTTGTCATCGTGGCGCATTAGGAGGAGCCTTCGATCATCGAAAAGCCACCAGTCCTCGGCGCCGATGCCAGGGATGATTCCCGCCTTTTGTGCTCCATGCCTGGTCAAGTACTGGATGGTTTCGCCCGCGCCGCGGTTGAACTTGTCCATCCAGCGCATCCACCGCTGGTAGTCGGTAGGCGGGGTTTCTACGATTCGCACGCGCCCGATCGTTCTGCCGTGGTTGACGTGCGCGGCAACTTGCTTCATCCACGAGCCAAGCTCTTCATTTTCAAGCGGCGACTCCGGATGGCCAGCAAGGAACTGATCGAACTGTGCCTGCTCGTAGCCCAAGTGATAAGCAGGCTGCTGCTCCCAGCGCCAAGCTGACCGCTTAAAAGTTTCGAACGCTCGCCAAAACTCGGTTCCAGGTCCGCCGTCGGTGAGGACTTTCCGCATTGCTCCTCCTACGACTTGTTCATGTCGGATGCGTGGTACTTCATGGCGGCGCGGAGCAGCTTTCGCGCCTCGTCGCCTTCGACCGCGTCCTGCCAGACGTCACGCATTGCGTTGGCATGGGCGGTCCATCCATCTGCATCGAGCTCGTCATCGTCGTAGTAGGTTTCAACGACACCAATCTTGCCGTAGAGCTCGAAACTGTTGCGGACGACATCATGGAAGGTGCCGTAAACGGGCAGGATGCCGAGCCGGACGTTTGGCAGGTCCATGTATTCCAGGATGCGGTCAACCTGGGAATACATAACTTCGGGTGGCGCCACTCGCCGGGTGAGCACTGTTTCGTCGATGATGAACTCGAACCGGTACTTCTCGTCGAGAAGGAACTTGCGACGCTGCATGCGCGCGGCGACAGCTTCTGCAACGTCGTCAGCGGTCTTATGCAGCTTCATCGAGCCGGTGAGCACTGCGGTCGCGTATTCGCGCGTTTGCATGACGCTCGGCACAAAGGACCGTTCGATCATGCGAACAACATCGGCCTGTTCAACGAGTTCGTTGTAGGTCTGCTGGTGGGCGGCCTGACCCTTCTTGAGCGCCTTTTGGAAGCTGGTGGTATGCCGTTCGGCATCTGCCAACATGACCAAGAGTTCATGCTCATCCTGTTCGCTACCGCCGGTAGCAGCAACCCAACTCCGGATGTCATCCGCCGTGGGCGTTTGCTGTCCCAGACGAAGCTTGGACACCTTCGACGGGATCCAGCCGGCGCGAGCGGCAAGATCGTTGTTGGAGGTCTTGGTGGTACCCGTGCTTTGTAGCTGACGGAGGCGTTCGACGACGCCTCCGGGCTGAAGCAGCCATTTCTTGAGTTCGCGGTCCTGCATGCGCGTGTCTCCCTCGCTTTCGTCAGGCGGTTTGCCAGGTCCCGCCGGACACGCGTCCGCTGGATCCGTTCATGTGGTAGTTCCACCTCTCAAAGAGGCTCGGGTCTGCATACGACTGCACCCAGGGATCCATGGAGGCGTCCCTGGGTAGCCGTGCTGATGCCGGGGTCCTAGCTGTTGAGCCGGTCCAGGACGTTGCCATGGACGAAGATGACATCCTCATCGTCGAGAAGCCCAGACCTGTTGGCTTCGGAGTGACTGAGGACTGCCGCCCGTTCGTCGCCGGTAACCACCCGGCCCTGAACGTAGTAACCGCCGTCTGTCTTGAGGATGGCGTGGCATCCGTTGCCGCCGGAAGCCACGTCCTTCCAGAGGAACTCGATGTTGAAATCTTGCATGGCGCCGCCTTCCGATCGCTGCGCGATTGCGAGAAATTCCTAGGCCAGCATCCCACCGAAGTATGAGATCACACAACAGCCCCGCATTCGAGGTCGAAGTCGGGGCTGCAGCGTGTCCTGGGGACCTGGCGTCCATCAGTGTAAGAGAAATTTCTAGCTTTTTCTTGACCGCAGTGTCCATCGAGCGCATGGTGTGGGTAGGCAAGAAGCCGTCGTCTCCCGGTCGGGGTTGGCGTGACTGAGACTCCCCTGCCCCGGCCGGAATGACCCCTCACCTGGAGGCATTCCGTGCACACCGCACCCGCCACCTACCCGTACAGCACCGCCCAGGACATGCTCCTGGGCGCGGGGCTCACCGAGAAGCAGACTGTTTCCGTCATCAGCAGGCTGAGCGAGGACGGCGTACGTGTTCTGGCCGCCAGCGCCAGCGAGCCGGCCCGGCAGGTTGTTCACGCTCTCGCTCACGAAACGATTGCGGGTCTCGCCGAAACCCTGCACATGCAGGCCGATCCGGACGTTGCTGTGGTCCGTGAGCTGCTGCGTCACGCGGTTGGAGCGTGGTGACAGTGCGGACCACCCATCCGCTCACTGCTGACCGCGCCGCCCTGGCCGCCGCTGGCCCGCAGGCTTTCGCTCTGACTCCCGACGACGAGCGCGAGATCGGCAACTTCCTGATCGAAGTCGACAGCCTTCCCGACGAAGACGCCGCGCTGAGGCTGCGCATCCCGATCGACATGGTCCCGCAATTCCGGCAGCTCATGGCGACGGGCCGCTGAGCTTCGCACCTACTTCGCATCCGCGCTTTGCACTTCACACCTGTACTTCCTAGCTTCACACCCGCACTTCCAGGAGGACCCGATGTCCACCACCACCTACGCCCCGCCCGCTGGCGCCGACAACCCGGACGACTTCGACCGCTGGGAGAAGGAGCTGGTCGGCGACACCCGGCACCACTTCCGGCCGTCGAAGGCGGCGCTGCGCCGCGAGGACCAGCACGCCATCGACGAAGCCCTCGGCTACCACCGGCACCGCACCAACGAGCGCAGGGACTGACCATGACCCTTCACCCGCAGGGAATCGACGACTGCCGGTGCGGTGACTCGGACTGCGTTGGCACGTTCGGCCGTGCAACTGCCGGCCAGGACCGGTCGGGCTGCTGCCAGTACTGCGGCCTCACGAGCTGCGACGTGTGCGGCTGGACCGCCCTGCCGCTGGCAGTTGCCGCGACAAGCGTCCGTGATCCCTTTACCGGCCCTGCCCACCACCAGCACGGCACCAACGAGCGACGGGAGAACTGACATGCCGTTCGACCTGTACCTGAAAAGCGCAAACGGCACGGTGGCCATCCGGAACGCGCCGGACAGTGATCGGGAGTTCGCCGAGTCCCTCGTTGACCTGCTCCGGCAGGGGATGCCCGCGGACGAAATCCTGACTATCGAGCACAACAGGGGCGCGATCTCCGTGCCTTGGGGTGAGCTTCGCGGCGTATGGATTGAGGACGTATGAACGTCTTCTCTTACCGGCTTGTCTACCGCGGCAAGGTCGAAGCCGAGGGTGTGAACAGCGACTTCCAGCATGACAACGCTGAGGACTTCGGCCGCGCTTACGCCGCTACCATCGACGCCAACCGCCCGCCTCGGCCGTATCCGCTGCACTTGCTCGTGTGGGAAGGCGAAGACACCAGCCGGGATCCGGACTTCAAGCATCGCTGTCGCCGGCACGTCGACCATGTTCTGACCGGGGTGGCGTCATGACCGCCACTATCCGCCGGCTGCTCGGTCGCGCTAACCGTCCCGCCAATCCGTTCGACCTCGGCGTACGCGTCGAGACTGGTGAAAACGAGTGGCACGGTCAGGTCCCGACCGGCGTTACGGTCATCCTGCTCGGCGACCCATCCCGGGCGGTAGCCCGATGACCGGCCATGATCTGGAACTGTCGGCGCCGTCCACGTGGCCGCAGGACGAACACGCGTTCTGTGGGTGTGGCCGGCTGATGCGGCGAGACGACGCCGGCCGGCTTGTGTGCGACGACTGCGAGACGGCGGCGGACGACGCTGCGGTGATCGTGGCTGAGGTGATGTCGTGAGTACCGTCTACGTGGCTGAGATTGAGGGCCAGGACCTGCGCCTAATCAAGGACGGGAATCCGAACGTCCCGTACGACCTTGAGGTGTACCCGATCTACGGGCACGACGACGCCGATCGGTGGCTTGCCAAGCATGGCTACACCGATCACGACAACTGGGGCTGGCGCAAGGCCAACAGTTCGAAGCCGGCGATCTGGCTGAAGAACGTGGTGGCGCCGTGACCGACCTGAACGCGCTGCTCACCCTGTACACGACCTGGTCCAAGGCTCTGGAAGCCGCCGAAAAGGACGGCCCTGAACAGTCGGCGATCCGGGCAGAGATCGCGGACTACGAGGCGGCGAAAGCAGCCCGGCAGATCGCCGACCTGCTCGCCGCCGAAATCCTCGAGCCGGCCTCGGTCTGACGGGCCGCCTCGCCCACCAGCACCAGCCTCCCCTCCCCCGGTGCTGGTGGGCGTGCCCGACCCGTACATGCCGAAGGAGCCCCATGCAGCACATTCACACCAACGCGGCGGAACTTATGTCTGCCCGCAACGGCACCACCACGTTCATGACCGTCGCGGACGGCACCTACAGCAACAAGGTGGCGTTCGACGTCAAGGGCGGCGAAATGGCGCCGACCGATGGCCTGCCCCGCGTGGTCCTGACACCCGACCAGTTCCAGAAGATCACCGCCAAGGACAGCCGCGACTACCAGGTCACCGCCGATGACGGCAGCGTTTACGCCGTGTCGGTGTGGGCCTGACCGGCCCCGAAAGGACACCATGATCCGCATCAGACTGGTTGACGGCCGCACCGTCGAAACCAACACCTACACCCTCGACCAGGCCTACAAGCTCATGGCCGATGGTCATCCGCTGCAGATCGGCGGCCCCGAAGACTGCGAGCTGCAGCCAGTCTTCGCCGACGACCCGCAGGGCGAGAACCCGCGCCAGGCCATCAACGCCGCGGCGATCGTCAGCATCGAGGAGGACGGCGCGTGACCGCCCGTATCCTTACGCTCAAGCCCAGCCAGATGCAGCGGCTTCGGCAGCAGCAGCACGTCTGGTGGGACGACAGCACCGGCCGCGAGGTACTCGTCCGCACCGACCCCGGCGGCAGGGTTGATACCTACCCGGGCGCGCTGGTCCTGACCCTAACCCCCGCCGACCTGGACCTGATCGAGACACCGGACGGCCTGGTATGCGCCGATGAGACCCGCACTACCGGCTGGACGGTTTGCATGGCCGAGGTGCAGGCGTGAGCATCGACTACACGGGCGAGGTGGTCGGCCGGGATCCGGTCGGCAAGACGATCGTCGAGGCGCTGGTTTCCTCGCACCCCGACTGGTCGGACCAGCAGGTCACGGACCGGATTAACCGGGAATACGACGAGCCGGTCATCACCGTGGCTGAGGTTGCCCGGTGGCGGCCGGGCATGGCCCGGTGACCGCCTACGATCCGGGCAGGTCCATAGGCGGCGAGCGTTGCAGCCGCATCGTGTCGAACGAGATGATCGATGCCCACCCCGACTGGTCCGATCAGCAGATCGCCGACCGACTCAACCGCCGGTTCGACAATCCGGTGATCACGGTCGACGAGGTGGCGCACTGGCGTTCCGAGCGGGCGACGGCATGAGCGCTTACGCCAACGACCCGCGGGTGAACGATGTGACCGGCCGCGGCACGCTGTTCCTCGTCGCCGACAAGCCGGACGGTGAGCCGGTCGCCCGGGTACGTCCGTTCATTGACGGCGCGACCTGGGTGGCGTGGCCGGTCGACGAGAACCTCATGACTGAGCTGCCGGAGTTCGGGACCGCCGATGAGGCCATCAGGTCTGTGATCGGGGACCCGCAGTGACCACGGTCATGTGTCAAAACCCGCTGTGCCAGTACACGAGCGAAGCCGTCCACGAGCTCCGGGTCGCCGGCACCAAGATGGTCCGGCTGGTGTGCGCGGACCGTAGCTGCACCTTCTGGGCGTCCGGTGAGCTGTGCAAGGACGTGCCGAACGCGGTGATCGAACGGGACGAACTGCATCCGGTCGACGCCGGCGGCGTCCACATCTACGACGACTTCTGACTGAAATGACGGCGGGCCCGCTGCGTGGATGTACGGGCCCGCCGTTCGAGAAGCCCTGGGAAGGAGATCTCATGTTGCACATTACCCACCGGTGGCGGCGTCAGCCTCCCCTGATCCAGGATCAGGCCGCGGTCATGATGGCCGACCTGCTCCGCGAGTCCAGCGGCAAACGCGACGACCGGCGGCCGGCTGATGGCTGACCTGCCCGCCGACCTGCTGGTGATCGTGCACCACGACGACAGCGTCACCCGGTACGAGCAGGTCACATACTGCCCGTGGCCTGGCGGGGTCACCGTGTACCGGAATGGTGAGCAGATCGCCGAGCACAACGACGTGATCGGCCAGCATGCCGAACGTGCAGCGGTACCGGCCTGAGCCCACCCGCTGACGATCGCGTCGCCGAGAACGCCGCCCTGTACAGGCAGTTCGGCGGGGACCCGTTCCGGCAGTGGAAGAACCCGCCGCTGAAGAAGCAGGTGGGACTACTACGACATCACCAAGCTCTGAATCCTTGATCACAACCTTGCCGAGTCAGCACACGGAGGAACGATGACCTTCCGAAACACCTACGTTGCGCCGATGACCACCAGCGCCAGCTCAGTCATCACCGCCATCAACACCCGACGGCCGGGCCTGAAGCCCGCAAAACAGCACATGCTGATGTTCTTTATGCAGGGCCACCACCTTGCCTGGCGCGACCGGGCCCTGTTCGACGAGCCCATGCACGCCACCGAACGAGCCGTTGAGATCGACGCCAGCGCGGACAGCGCTGAGCCTCAGATCACGGACGAAGCAGCCCTGAACACCATCGGGTACGTCATCGCCCGGTACAGCGCACTGTCACCAGCCGACCTACGCACCCTCATCCAGGCATCGCAGCCGTGGCAGACAGCCACCAAACCGGGCTCCGAATCCCGCATCGAGTGGGCGCACCTGCGCGACTGGTTCCAGCGCCCGGACGAGACCGACGACCCGGACGATGAGCGACCCAACCGTGCCGAGGTCGCCGCAGCCGAGGCCTACCTGACGTCTCGCGCCCGGAAGCTGGCAGCAGTCTGATGGGTGGCTACCGGTTCGAAACGGTCGATGCCTGTGACGGGGTGATTGACCGTTGGGAGGCGCAGTACTTGGATGATGCCGCCGCCCTTGACGCGCTGGCGTGGCAGCCAATCGGGTCAGGTCTCGAGGTGCGACTGTTCCGGACGGCCGATGTTGGTCCGTTCGCAGTTAGGGAGTCCGGCCGCGAAGTGGAATGGACCGGTAACTGAAAGAGGCGCCCCGCTACTCCTGCGGGGCGTTCTTTTTTGGCCGGCCACGTGGCGTCTCGGCATCCACTTCGACCATCAGAGCTTTGAACTGGGCGAGCCGGCGCGGATCGTTGCGGACCCAGCGCAGCACGGCCCGGAAGAACGTGTTCATGGTGAAGCCAGCCCTTTCCACCTCGGCCCGGACTGGGTCGTACTCGTCGTCAGCGGGTCGATAGTTCCGGTTTACGTGCCGGTGCTGGCTACTCACTGCCGGATCATCCCATAGGCGGCTTGCCACCTTCTAGCAGCACTGAGACACTACCCTTTAGTGGCTTGCCACTAATTCTGCATCACGCTTCAAGGAGAGCCATGCCCGACACGGACCTGACCGCCCGCCTGCACCGCCTGCTCCACCTGTACCGGGCCCTGCCCGACGACCGGATAGTTCTCGCCGCGATCGTCGGCGACGACGCAGACACCCTCACCCTCGGCGACCTGCGCGAGCTGGCCCGACTGGTAGGCGCCTGATGACCACCATGGAGGACCTGTATCCGGACGGCCACGGCTACCACGATGCGCACGGCCCGTACATCGACGCCGTGGCCAAAGCACTCGACGAGGCCGGCTTCAAAACCGACATCTCGTGGTCGGACCCAAACGATCCGCGAGACGGCTGGATCGGCTTCGACATGGAACAGCAGCCCCACCGAAACGGCGAGCCGGTCTGGTCCTACGACGAAGTCGGTATCGGCTGGTCCGAAAATCGCGGCTGGCACCTGCTGTGTATCGACGACCGCAACGGCCGGGACTCCCGGTACGTGTTCGAGCTCGCTATCGCCCGGCTGGCGTCACCGGAGACGGTGGCGAACGCGGTCGCGGAGCAGGCAGGCATCGACGCGCACGTTGCGAGCGACGACTACCCGGACGTCGACTTCCCGGAGCACACCTTCGAGGACGACGACATCCCGTTCGACCAGGCGCTGGCCCAATACCGGGAGCCGGCGTGAGTGTCCGTCAGGTCAACAGGGACACGGTGCTGGCCGCGATCCGCAGTGGCGCCCGGAGTCTTGATGACATCGCCGCCCACTTCCAGGTGCTATCGCACTCCCCCACCCTTCGCCAGGTGCTCGACAGCCTGCTCAACGAGGGGCTGATCTACGACGGGCCGGACGGGCTGCACGCCCACGGCGAACAACTCACCATCGACGAGGAGAACTGACATGTCCTTGATTGGAGGGCGCATCCGCGACTTGATCTATGTCGAAAAGGAGCACGTCAACTTGGATGAGGCGGCTGCGATTGCTCGGGTGCTGCGGTGCACCGGCAAGTACGGCGCCGGCCGGCCCGAGGTGCGTACCGATGAGATGGTAACCGACGTACTCGCCGTGATGCAGGTGCTGGCAGGGCCGGACGGCGACAACGCCCGTTACCTCAGCCGGAGCGCCTGATGGGTGCCGGCGCGCTGGCGGAACTGATCGTCGCCGAATTCGGCCTGGACGGAGACGACCAGTGACCACGCTCCGCGATGACCTGGCCGTGCTCATCCGCGAAGCCGACAAGGACAACGAACTGAGCCCGTACCAGCTTGCTTCCTCGATCAGCGAATTCCTCCTCGACCGCGGCCTGGTCACGCCCGTGCAGGCACACGCGGTGTCGGACTTCGCTGAGGAACAGAACCGCGGCGCCGGCTACCGGCACCCGAAACCGGTCGGCCCGGAAGCCCTGGCCGCCGTGATCGTCGACCGTTTCAACCTTGAGGAGAACTGACCATGAGCTTCCACCCGCCCGCCGACGGACGCTGGGCCATGCAGCCCCGCCTCTTCCGCATCGGTAACACGACCCTGCTGGACGACGATCCGAACCCGTGGACCGTCAAAGCCGTTACCGCCAACTTCGCTGTGCTCACCCGACTGGACGATCCCGAGTGGGAAAACGGCGACGATGACCCGGAAGACGGTCCGACCAGCAACGACTGCGACGTCCTCTATACCGTCCTGGACTGCCGTAACGGCTACCGCGGCCCGTGCAACCTGTCCGGCTGGGGCTACGGCGACGGTACCTACAGCGAGGCCGACTGCGCTGCGATGCTGGCCGACTTCGAGGCTGGCGACCTGGAGATCAGCCATCGAAATTGGACGCGCATTAGGTTTGCAGACGAGGCGGCCGTCCGATGACCGATACCGCCGCTGTTCCGCTTAAGGATGTCGTTCACGTACTCCGGCTAGCCCGCGACGGACAACTCGGCGGTACTAACGATTGGACAACCGAGGGGTTTGTGTCAGCCGTCTGGAACGGCTTTATCACGAAGGACGACACCATGGGCCTCACCCCCGCCGGCGAAGCGTTCCTCGGCAAAGTTGGGGTGCTGTTTCCGGAGGCGACCCGATGACCGTCACCGTCACCGACATGCACATCCCGGCCCAGCGCGATCCGGGCCACGACCAGATGGTCACCCCGGAATCGGCGCGGGTGGCTGAGCTGCAGGAGATGATTCGGTCCGGCCAGTACGCCGGCTACCTGGACGAACTCACGGATGCGCTGGCGAAAGCGAAAGCGGCCCGTGACGAGATCCGACAGCTCACCGCGACCAGCGCGCTGGGGGCGTGACCATTGAGCTGGTATTACGTCTCCTACAACTTCGGATATTCCCGCGGCAGCGGTTTCGGCAACATCGAACTGGTGCTGGATGAAGCCCCTCGCCCTGGTGGTGCTGGCGTAAAGGCGCTAAGGCGTGTTTTAGAAGCTGATGGTTGATCGATGTTCCGGCGTGGCGGTGATCGATAACTGAAGAGGTCTCCGGTATCTGGTTCTGCGACCAAGCAAGAACTTCATACCGGAGACCTCGTGGCCACCTTAGCGGTGACGAGGCGGCATGACCTGACCGACCGGCAGTGGGCCGTGCTGGCCCCGCTTCTTCCTGCCGCGTCCACGACAGGTCGTCCGCCGAAGTGGGACAAACGGCAGCTCATCGACGGGATCCGGTGGCGAATCCGGATGGGCACCCCGTGGCGTGACGTCCCTGCCGTCTACCCGCCCTGGCAGACGGTCTACGGCCTGTTCCGCCGCTGGCAGCGCGACGGCACCTGGGACCGGATCCTCGCGGCATTGCAGGCCGCCGCCGATACCAACGGCAGGATCATCTGGACGGTCAGCGTCGACTCGATGACCAGCCGCGCCCATCAGCACGCCGCCGGCGCTCGCACCAACGGCCACCTGCAGAAAGAGCCACCCGGCGGCGTCCACGACGAACCCGCCGACCACGCACTCGGCCGTTCCCACGGCGGTTTGACCACCAAGACGCACCTGGCCTGCGAACAGGGCCAGAAGGTGTTGTCGATGGTCGTGACCGCCGGGCATCGCGGCGACAGCCCCCAGTTCATCCCGGTCCTGCGCCGCATCAGGGTCACCCGCCTCGGTGTCGGCCGGCCCCGCACCTGTCCCGACCTGGTCCTGGCCGACAAGGCCTACACGAGCCGAGCCAACCGTGCCTACCTGCGCAAACGAGGGATCAAGGCCTGCATCCCCAGCAAGAAGGACCAGGACGCCCACCGCAAGGCCAAAGGATCCCGCGGCGGACGCCCGCCGAAGTTCGACAAGGCCCTCTACCGCATGCGTCACGCCGTCGAGAACAGCATCGCCCGACTCAAGCGCTACCGGGGCATCGCCACCCGCTACGAAAAGCTGGCAGTCCGCTTCCAAGCCGCCCTAACCATCGTGATCATCGGCGAGTGGCTATGACCAGCTTCTAAAACACGCCTTAGGTCCGTCGCTGGACGTCTTGGCACCGGTTCACCACCCTTGCCCTGGCAGCGCTTGCGGTCCTCGCGATCTGCACCGCCGACGTCCGATCGGCGGACCGTCCCGGTCAGCCCGACATGATCGACCTGACCGTCAACGAGATCCGCCGCCTGATCAACGTCCTACTGATTCGGCCGGCACGCAGCATCGCTCACCGTTTGCGTTGGTCACGTTGGCGACGCCGTCACCAGGCACGAGCCAGACGAGCCCACTACGCCCGCCGCCTCACCCTCAAAACTCAGCCATGATCACGAATGGCGGCTGCCCTACTAGAGAACACCGGCACTGTCAACTGGTCAAGCTCGAGGCTCAAACGAACCTCAAGGAAGAACCGATATCGAGAACCCTTCCTGTTTTGCGGCCGTCGATGTCTTAACGTAAGGGCACGCGCGCGGAATCTGTCTTCTCGAAAGGATCTCGATGTCCATCAAAAGGTTTGTCGCCCTGGGCGTAGCCGTACCGACATTTCTGACGGCCTCGCTCGTGGGATTGGACCAGGCGGCCATGGCGTCGCCCGCACCCGAGGCTGTCAAGCCCGCCTCGGTCGCCCCGATCGTCGCTTTCAACGGTTCGGCCGATCCGCAGTTCTGGGGTGCCGTCGCCCAGGCCGCCGCCAACGCGGCCGCCGGGGCGGTGGCGGCCGCGGTGGTGGCGGCGGCACTGGCTCCGAAGTCGTCCAGCTCCAGCTCCGGCGGCCCAGCCACCGGCACGGCCGCGGATCGATCCGGCGACGCGCAGTTCGACGTGGCCAGCTGACGCCAGCTCCGGCGCTCTCTTTCCCATAGTGGGACAGCCCTGCCGGCGGTGACCTACGGCTGCCGTCGGCAGGGGACCACTCTTTTCTAGAAAGGTTACTTACGGTGCGGGCGATTGCATTGTTGGCCGCGGCGGCGGCAATAGTGATGTCGGTAGGAAATACTTTTCCGGCCGCTGCCGAAACAGCGGGAAGCGCGGTCGCCCGCCTCTATATCGACGTACGCGATCAGAATGATCTTGATTCTCTGGCACGGGCAGTCACCGATCCGCGGTCGCCGTCGTACCGCCATTTCCTGTCGCCCGCCGATTACCGACGGCGATTCGCGCTCACCGATGCGCAGCACCGCGACCTGCTGACTCGGCTGGCCGCCGACGGCATCCGGGTGACCGGCGAGACCTCGCACTACCTGCGGATCACCGGCCCGGCCGCGGCAGTCGCCCGGGTGGCGGGCGCCAGCGCTGCGGCCCATTCACTGTCCACCCCGGTCAGCGCGGCTGCCGACGCTGCCGCGAGGCTGGCCGGGCCACAGGCCCGGGTGCGAGAGAAGGCGGATGCTGACGAGCCGGCCAAGTGCTCCTCCTGGCTCGGCGAGTCACCGGCGGCCGACATGCCACCCGCGTACGGCAGCATTTCGTCCTACGCCACCTGCCCGTACCGCCCGGACCAGCTGCGCAAGGCTTACCACGTCACGACCACCGGCCGCGGCAGGACCGTGGCCATCGTCGGCGCCTACGGCTCGCCCACCATGCGCGCCGACGCCGACCGATTTGCCACCGCTGTCGGCGACAAGCCGTTCCGGCCCGGCCAGTACCGCGAGGACGTCGACCCGAACGCGTGGAACCTCACCCCGGACTGTGCGCCACCTGCTGATTGGGCCGGTGAGCAGGCTTTGGACGTGGAGACCGTGCACGGCTACGCGCCGGACGCCGCCGTCCGCTACGTCGGGGCCAACTCGTGCCTCGACGAAGACCTGATGGACGCCGAGAGCTCGATCATCGACAACCGCTCGGCCGACCTGATCACCAACTCGTGGGCCGAGATCATCCATGCCGATCCCGGCCACCTCACGCCCGACCTCGTGGCGGCCTGGAACCGGCTGTTCGAGCAAGCGGCCGTCGAGGGCATCGGCGTCTACTTCGCCTCCGGTGACTGCGGCGACGCCTCGCCGGGTGCCGCCCACGCAGGACTGAACTGCGACCCGGCCACAACCGCGGCCCAGGCCGAGTGGCCGGCCGCCTCGCCGTGGGTGACGGCGGTCGGCGGGACGGCGCTAGGCACCGATGCACACGGCCGGTACGCCTGGGAGACGAGCATGGGCGACGACCTCTCAATCCGTTCGGCGGACGGCACGGCCTGGACGCCGCTGCCCGGGGTCTTCGTCTTCGGAGGCGGCGGCGGGCCGGGCGACGCCCCTCAGCCGTGGTACCAGCGTGGCGTGGTGCCGGCTGCGCTCGCTGCGGCCGGGGGTCAGGCCCGCCGCGTCACCCCCGACGTCGCGCTGGAGGGCGACTTCGCCGTGCCAGTGCTGGTCGGCTATACCCTCGGCGGGACGTTCCAGCTGATCGGGTACGCCGGCACGTCGGCGGCCAGCCCCGGGTTCGCGGCCATCCAGGCCGGCGCCGAGCAGGTATCGGGGCGCACGATCGGGTTCGCCAACCCGCTGCTGTACCGGCTGTCCCGGGCTGGTGTCCTGCACGACGTGACCGAGCCGACCGCACCGGTGACGGCGGTGCGCGATCTCGGCGCCGACCAGGGCGATCTGCGATACGTCCTGTTCACTCTGGGCCAGGACTACGGCCTGTCGGCCACCACCGGGTACGACGCCGCTACCGGCTTAGGCTCACCCGGTCCCGCGTACCTCTCCTGGTTCCGAAGGCACTGAGTTCACTGGGAGGAACGGAACCGTCATGTCCCCACGCGAAGCCCTACCCGTGCGCATCCGGGTCGCCGTGCCGCTGCTACTGCTGGTGGTGGCGCTGTTCACCGCGGCCACGCTGATCTACAACGCGCCGGCCTCACCGGCCCGCAACCGTCTCGACTTCGTGCCCAAACTCCTACAGCCCTACTTCTGGCAGGACTGGCAGCTGTTCGGCCCCAACCCGCCGGTCACCAACAACCTCATCTACCTGGAGGTGCGGCTGCGCGACGCAACCGGGCAGGTAACCGAGAGCGCGCCGGCCGAGATTGAGCAGGCCATCGACCGGCAGCCGCGCAGCTTCCGGACCAATCCGACCAAGACCCCCGGCATCATGCTGGCCTTCAACGCGTCGGCCAACAACTTCGCCCGGGCCGCGAGCGCGATCGCCAAGATGCCGGCCGATCAGCAGGCCGACGCCCGCAAGAAGCTGTTCGACGAGTACGCCAACTTCTTTGTCGAGATGCAGCGGTTCTTCTCCGCCAGCGCCGACGGGCTCTACCCGGGCCGGGACATCGTCGCGGTGCGGGCTCGGTTCCGTACGCGATCGATCGTGCCGTTCTCGCAGCGCTACCAAGACCCACCGCCGGCACAACCCGAGAAGGAACTGCTCGACACGAGCTGGCTCACCTACATACCGGGGATAGCACGATGAACCGACTCGACACCTTCCTGGCGCGGATCAGCGTGCGCGAGCACCGGCTCATCGGCATCGCGCTGATGCGCATCGTCATCGGGTTCGCGACCATCCTGTACTGCCTGGCTGACTACGACCGTCGTGAATTCCTTTGGGGACCGACGTCGTACTACTCGGCCGGCGTCGCCCGTACCGCCTTGCCGCACCACGGGTTCTCGCTGTTCCTGCTCAGTGACTCGCGGGTGTGGTTTGAGATCGTGTTCCACCTAGTCATCGTCGTCTCACTGGCGTTCATGATCTTTGGTGGGCGATCGTTGACCATCGCGCAGGCGGTGCTGCTCTGGTCGCTGCACTGGCGCAACCAGGATGTCCTCGAGGGCGGCGACAACTTGGCCCAGATCGTGATCATCTTCATGATCTTCACGGTGTCCAACGCCTACTTCGCGCCCGGAGCCCGCAATCGCCGGGAGCGCATGCTCGCCCGGGAGGCGCCGGTCCTGCGGACCGCGGTGCACAACCTGGCCGCGTACCTCATGGTGTTCCAGATCTGCGTCCTCTATTTCATGGCTGGGTACTGGAAGGTGACCGGCGAGCAGTGGCAGGACGGCGTGGCCATGTACTACATCAGTCACGTGACCGGCTTCGCGCTGTCATCCACCTATGCGGCGTTAATGAGCAATGCGTTCATCGGCACCGCCGTCACTTACTTCACCGTCTTTACCGAGCTCGCGTTCCCGTTCGCGGTGCTATCGGTGCGCGGCTGGGTCCGCAAGACGGTCATCCTCGCCATCGAGGGGATGCATCTGGGCATTATGGTATTCATGGGTCTAGTCTGCTTTGGGTTGTTGATGCTGGGCGCTGACAGCGTCTGCCTGCGCGACGACGACTACAAGACCATGTACCGGTACGCGCTGAGGCTGCGTGACGCGACCCTAGCCCGTTATCGCCGGCGCTTCACTGCGCCGGTGCCCTCAGCGGTCGTCGCCATGGAGGAGGACACGCGTGTCGCCGCATGATGCCCAGGTGCGGGCGCTGGACGCGTTCTTGCGCGCTGATCCGCAGACCTGGCCGCGGCTGGCGCCAGCGCTGGTGGCCCGGGCAGGTGAGCAGCGGCTTCGCGAAGTCGTTGACGAGGCCCACGGCCGGCTCGGCGGCATCACCGGCGTCATCGATACCCCAGACGGCCTAGCGATCGAAGGACCGCAGGGGCAGGTGCTGGCCTGGGCCGAAACGGACGAGGGCGGCGCGCTGAGCGGACTGTGGATCGCCGGGGCACGGCGCGGACGTGTCCGTTCCGGGCGCCGGGCTGAGCTGATCGGGTACGCGGTGCCCTACGTACCGATGCTGTGGGGGGCGATCGGCTGCTGGACAGCCAGGTCGGTGCTGGGCTGGGCTGGGCTCCTGCTGACCACCGTGGCGATGTACACGTTCATCCGCGGGCTCGGCGCTCTGCCCGTACGGCCTTGGTGGGCGAACCATCCCCTCACTCTGCTGTTCACTCTCGCCCTCGCCTCGACGGCCCGCCTGCCGCGGCTGACCGCTGAGGGCGGTGCCGACAGTCTGATCGTCGGCGTCGTTCTGGTCGTCGCGGTAGTCGCGCTGCTTGTGCCGGCCCGCCGGCACCGGTGGCCCGAAAGCACCGAGCGGCCGCTGGCAGTGTTTCCCGTCGACGGTGACTGGTATGTACTGCAAGGCGGCGGCCGTCTGATTAACCATCACGCTACCGTCCCCGAGCAGCGCGGCGCCGTCGACCTAGTCCGCATCGGCCCCCAGCGGGGTGATGCGAGCCGGCTCGAGTCGTACCTGGCCTACGGCGAGCCGGTCGTCGCGCCCTGCGCCGGCCGGGTCGTAACCGCCGTCGATGGCATCGAGGACCAGGCGCCCGGCACGATTCGGTTTGCGCCCCCGTACGGCAACCGCGTGACCATCGACAACGGCAGTGAGCTGGTCACAGTCGCCCATCTGAAACCGGGCACGGTCACCGTCCGCCTCGGCGACACGGTCGAGGCCGGCCAGCTGATCGGCGCGGTCGGCAATTCCGGCAACAGCAGCATGCCCCACCTGCATCTGCAGGCCGACCGGGCCGGAGTGGGCCTCCAACTGCGCTTCGCCTGCATCAACGGCTCGCTGTACCGCGGTCGTCGCGTGCGCGCCCCGAAGCGGCGGCCATGATCGACGTGATCGTGGTCGGCTCCGGCCCCAACGGCCTGGCAGGCGCGGTCGCGCTGGCCAGGCAAGGCCTGACCGTGACCGTGCTCGAGGCGGCCGAAACCATAGGCGGAGGCACCCGCAGCGGCGAGCTGACCGTCCCCGGCGTGCTGCACGACCACTGCTCCGCGGTCCACCCGATGGCGGTGGCCTCACCGTTCCTGGCCTCGCTCCCCCTCGACCAGCACGGGCTGACCTGGACCTGGGCGCCGGTGGAGCTGGCGCATCCGCTCGACGGCGGCCGGGGCGCCGCGCTGTACCGGTCGATCGAGCGCACCGCAGCCGCGCTCGGCGACGACGGCGCGACCTGGCGACGGCTGTTCGGCCCGCTGGCCGCGGACTTCGACACGCTCGCAACTGACCTGCTCGGCCCGGTGCTGCGGGTTCCCCGGCATCCGGTCCGGCTCGGCCGCTTCGGACTGCGGGCGGCCGCGCCGGCGTCGGCCCTGGCCCGGCTGTGGCGTACGGCCGAAAGCCGGGCGCTGTTCGCGGGGACCGCCGCGCACGCCATGCGGCCGTTGCACACGCCTGGGAGCACCGCCATCGGGGCGATGTTGATCGCGGCCGGTCACCGGCACGGCTGGCCAGTGGCCCGGGGTGGTTCCCGGGCGATCACCGACGCGCTGGCCCGGCATCTGTTTGAACTAGGCGGCACGATCCAGACCGGCGCGCTGGTGCGGTCGCTGGCCGATCTGCCGCCGGCCAGGGTGGTGCTGCTCGACGTCGCGCCGTCCGCGGCCGCGCGCATCTGTGGCGACCGACTGCCGCCCCGGGTCGCGCGCGCCTACCGCCGGTGGCGGCACGGTCCCGCGGCATTCAAGGTGGACCTCGCAGTCGAGGGCGGTGTGCCGTGGCGGCTGGAGGCGGCCCGGCAGGCGGGCACAGTGCATGTCGGGGGAGAGCTGAACGAGATTGCGTACGCGGAAAGGCAGGTCACCGACGGACGCCTACCTACGCGGCCGTTCGTTCTGGTCGCCCAGCAGTACCTGGCCGACCCGGCCCGGTCACAGGGTGACATCCACCCGGTCTACGCCTACGCTCACGTGCCGAGCGGATGGGACGGAGACGCCACCGACGCCGTCCTCGACCAGATCGAACGGTTCGCGCCCGGACTGCGCGAGCGGATCGTCGCCCGGTCGGTGCATACGGTGTCCCAGTTCTCTGGCGGCAACCCCAACTACGTGCGCGGGGACATCCTCACCGGGGCCAATACGCCGGCGCAGCTGGTGGCACGGCCGCGCTGGGCCATCGACCCGTACGCGACCGGCGTCCCCGGCGTCTTCCTCTGCTCGGCCGCCACGCCGCCTGGCGCAGGTGTACACGGCATGTGCGGCTACCAAGCGGCCCGATCGGCGCTCCGTCACATTCAGTCGACGAAGAGCTTGGCGGCTCGGTAGTACTGCTGTGCTCCGGGATGCAGCGGTACCGGATACGTGCCCAGGGCCGAACGCGGGTCGATCTGCTCGGCGTCGATGTGGGCGTCGCGCAACTGGAAGCCGGCCTCGAACAGCAGCGCGGTGAGCCGTCGGGCCACGTTGTCGGACATGTCGCGCCGGACCACTAGCACGTTGGTGATGCCGATCGTGCCGACATCGGCTGTCATCCGATAGGTCACTCGGGGGACGGTGCGCTCGGCGTACACCTCGCCGAACTCCGACTGCAGCCTGCCCACCAGCTGGCTCAGCGGCAGCAGCCGGATGATCCCCGGCTCGGCCCGCACGAGGTCGTTGATGGCCGGGGTCGGGAGACCAGCGCTGAAGAAGAACGCGTCCAGCGCGCCGGCCCGGACCCCGGCCACGGCGGTCGACAGGGACTGCCGTGCTATGCGTACACGTCCGGCCAGCCCGGCCGCCGCCAGCACCCTCTCGGCGGCGATGTCGGTGCCGGAGCCGACCTCGCCGGTGGACACCCGACGACCCGCCAAATCGGCCAGCGTGCCGATGCTCGCGTCAGCCCGCACCACCAGCTGCAGGTAATCGTCGTAGAGGGCGGCGAGCGCGGCAATCGGCACCGGCGCCGGGAACGGCGCCTCACCGCCTAGGGCCAAGCTGGCGCAGTCCACCGTGGTGAAGCCGATGTCGGCAGCCCGGTTGCCTAGCAGCGTCATGTTCTCAATCGAGGCGGCCGTGCGGACGGCGCTCATCTGCAGGGCGAAGCGCTGGCCGACCGACGCCAGAGCGGTTCCCAGCCGGTCGTAGACGCCGCCCACGCTGCCGGTCGCGATCACCAACTCGTCCGCTTCCGCGCTTGAGCCACTGCATCCCGCCGCTAGCAACGCTGACCCAAGCGCGAGCCGACCGAGATCGCGGCGCTTCATCGGGCATCGCACTCAGTTCTGGCGGCAGGCAGACGGACCGTCGCACGCAACCCGTGTGGCCGGACGCCGGCCAGTTGAAGCTCGCCTCCGGACGCGGTGACCAGCGCGCCGATGATACTCAGGCCCAGGCCGCTCCCGTCGTGCACCTGCCGGGACGGGTGCCGCCAGAACGGCTCGACCGCATGCAGCAGCTCATCGTCCGGGATGCCGACCCCGTCGTCCTCGACGGAGACTTCGACCCAGCCGGGCTCGGGGGCCGCCACCTCTATAAAAATGCGGGTACGCGTCTCACCGTACTTCACCGCGTTGTCCACTAGGACCTCCACGGCTTGGTCGAGCACTGACGGTGCCACCCGCACCCACCGCGGCCCGGCGGCCCGGCAGACCAGCTGCACTCTAGCCGCCTCGGCCATCGGCTGCCGCGCCGCTACCCACGCCTCGATCGCGGGCACAGCGTCGATCTCGGTGGCCGCGGCGGCCCGGGCGTTGGCGCTGGCATAGGCGAGCAGCGAGTCGATGATCGCGGCCGAGCGGTCGGCCTCCTGCACCGCAATCTCGTGTGACCGGTCGCGCTTGCCCGGTGCCGGCGCGAGGTTGTCGAGGGCAATGCGCAGGGAGGCCAGCGGGGTGCGCAGCTGGTGACCCGCATACGAGACGAAGGAGCCCTGCCGATCGATCAGCTCGGTGATCCGGTCGGCCATCTGGTTGACCGAGGCGGCCAGGCGCTGCAGCTCCGGCGGTCCGGACTCGGCCGCCCGGCTGCGGTGGAGCTGCTCCGGCAGCGATGTCACCATCGCGTCGAGATCGTACACCGGGCGCAGGATCCAGCGCACCAGCGGCTGGCCGACCGCGATGCCCGCAATCATCGCTAACACGCCGCATGCCGCCAGCACCGCCAGGTAGCGCCAGACCTCCAATTGAAGTCCGCGTACCGGTGAAATAGTCAGAATGCCGCCGATAATCTCGCCGCCGCGACCGATCGGGGTCGCCACCACCAGCGGCTGATCGCGCCAAGGCCAAATCGCTCCGCTCACGTCGTGCCGCTCGCCCGTGAGCGCCTCATCGACGTAGCGGCGCAGCATCGCCCGGCTAGCCACCTGACCGTCACCCTGCTCGAGGACCGTGACGCCGTCACGGTCCACCAGCAGTACGTCCACGCCGTAGATCTGGTGGTACTGCCGCAGTTCCATGCTCAACGCCGTAATGTGGCCGGTCCGCAAGGCCGGGTCGGCCAGCGAGGCGAGCCTGTCGGTGTCGTTAAGCCGGTCGATGAACATCGCCTGGGTGTCGCGGGTGACCGTGGAGATGGCCAGCGGCACGATCAACCCGGTCAGCACCGCGGCCAGCAACACCGAATAGCAGCTCATCAGGCGGTTACGCACAGCTAGCCGGCGTTTCCGTCGCCGCGCGGGACCAGCCGGTAGCCAACGCCGCGCACGGTCTCGATGGTGACCGCCCGCCGCAGCTTGGTGCGTAGTGAACTGATGTGCACCTCGAGCGTGCGGGCCGCCGACGGGTCGGCCGCCTGCCACACCCGCACCATCAGCTGGTTCTTGCGCAACACCGAGCCCGGTGCCTCGGCCAGGACGCCGAGCAGGTGGAACTCCTTGCGGGTCAGCTCGATCTCGCACCCGTCCACCGTCGCCCGGTGCCGATCGGGGTCGAGGGTGAGGTCGCCTAGGGTCTGCGCGGCCGGCAGCAGCGGGCGCCCGCGCCGCAACACAGCCTCGAGCCGCGCCTGTAGCTCCATCACGCTGAACGGTTTGATTAGGTAGTCGTCGGCGCCGCGGCGCAGGCCGATGACCTTGTCACCCAGCGCGCCGCGGGCGGTGAGGATGATGATCGGTACGTTGCTGTGCTGCCGGATCCGCCGGCACACGTCTAGGCCGTCCAAATCGGGCAGATTAAGGTCGAGCAGCACCGCATCGTACGCCGAGACTGCGACAGCATCGCCGGCCCGCTCAACGTGGTCGAGCTGGTAGCCGATCTTCCCGAGTGCCACAATGAGCACCTCGGCGAACCGGGTGTCGTCGTCGACAAGAAGCATTCGCATGGACGCAGTCCCCGTTTCCCCGCCGGGTTTGCATCGGCCGCCACCGCAACGGCGACCTTGGACTCCATGAGAGGGCGGCGAAGCGCCCGGACAACGCGACTCACCGATAGACACCACACTCCCCCTGCGTTGTGACGCACGGAAGCATAGCATTGATCGACAGTGGTGATTCGCCTCGATCATCGGGCTGCGTGTCGACGCAGCTGCCAAGAGGCTGATTGGGTGGTGCTGCGAACTGGCGCGCCTCAGCCAGCGAGCAGCGGCGGTGCCGCGGGAATCCGCCGCCCGGCCCGCATCTGCTGGCGGCGTTCGGCCTTAGAGGGCATCTGATCCTCTAAGGGGATAGTTCACGTTTGTGCACGTCATCGGCTGTGATCGTTCGTTGGTCGAGCATGGGGATGGAGCGACTTCCATATCGAACTGATCTGTCGGATGCGCGGTGGGCGTTGATCGAGCCGGTTCTGACGCAGTGGCGTGAGGCACGGCGGGGTCTGGGGATCCGGCCGCCGGTCCATGATTTACGGGAGATCGTCAATGCGATCTTGTATGTGGCGCGGACCGGCATGGCGTGGGAGTACCTGCCGCACGACTTTCCGCCGGCGAAGACCGTCTATGACTACTACGCCAAGTGGGAGGCCGACGGCACCACGGCCCGCATCCACGATCTTCTACGGTCGTGGGTACGTGAGGCGCTCGGCCGAGACGCCGAACCGAGCGCCGCGGTGCTGGATGCTCAAAGCGTCAAAACGTCTTGCAACGTAAGGGAATCCGAGCAGGGCATCGACGCGGCGAAGAAGATCAAAGGGCGGAAACGGCACATCGCTACCGACACCCTCGGACTGCTGCTGGCGGTCGTGGTCACGGCGGCGTCGGTGTCCGATTCCGCAGCCGGCAAGGGCCTGCTGAGCACGCTGGCCGCCGAGCATCCGACGGTGAGCAAGGTCTGGGTCGACGGCGGCTACCAGAACACCGTGCTCCGTCACGGCGCAGGCCTCGGCATCGACGTCGAGCGGGTGCCACGCCGTGCGGAGAAAGGATTTCAGGTCCTTGCTCGCCGATGGGTGGTCGAGCGGACGTTCGGGTGGCTGATGCAGCACCGACGCCTAGCTCGCGACTACGAGGCGCTGCCGCAGCGATCGGCCACGATGGTCTATTGGGCGATGACTAACACAATCATGCTCAGACTGACCGGCGAATCCACCCAAACTTGGCAGCGGCTATGACTGCATTCCCTTACCAAGCGGACAATCCGGGATCAGATGCCCTCTTAAAGCACCTAACACGATCTGTTGAATCGATGTTCATCAGCGTTGCGGAGTGAAGATCAGTCTCGTTCCGGTCTTCGTGAGCAAGGCCTGGGTCATCGATGACGAGTTGTGGAAGCTGATCGAGCCGGTGCTGCCTGCTTGGCCAGCGAGGGCGCCGGGACCGCGGCCGGTGCCGGACCGGCTGTGCTTGCAGGGCATCCTGTTCGTCCTGCACACCGGGATCGGCTGGGAGGACCTGCCGCAGGAGCTCGGGTTCGGCTCGGGGATGACCTGCTGGCGCAGGCTGCAGCGGTGGGCCGAGGCAGGCGTGTTCGACCAGGTCCACCAGATACTGCTGGACAAGCTGAACGCGGCGAACCGGATCGACTGGTCGAGAGCGGCGATTGACGCCAGTCACATCGACGCTAAAAAGGGGGTGCCGGGACAGGCCCGTCGCCGGTCAACCGGGGCAAGCCCGGCTCCAAGCACCACCTGATCTGCGACGGCAACGGCACCCCGATCTACGTGCTGACCAGCGGCGCGAACGTACCTGACATCAAACGTGCCCTGGATCTGCTCGACTGCTACCCGCCGATCGCCGGCAGGCTGGGCCGGCCTCGGCGCCGGTTCGCGGCGCTGCTGGCCGACAAGGCCTACAGCAGTGCGGCGTTCCGCCAGGCCTGCCGTGAACGTGGCACCGAACCCCTCATCCCCAAACCGAAGACCACCGGGATCAAGGGCCTCGGCAAGCTCCGGTACGTCGTCGAGCAGACCTTCGCTCTGCTGCATCAGTTCCGCCGATTGGCTGTTCGCTGGGAGCGCCGCCTCGACATCCACGACGGCTTCGTCAGCCTTGCCTGCGTCCTGATCTGCTGGCGCAGATTGATCAATTGGACCGATCAGAGATCGTGTTAGGAGTTTTTAGCTGGCTACGGGGTGGTATGAACGGGCACGTGACTCGCAGACCCGACCCGATGGCCCGCCGCCAGTCGCAGCCGCGCGCCGACTTAGTGCATCGTTCAGCACCGTTCCTGCCGTCAGACAGTGAAATCCGGCAGGTGTTCATCTACCAGACTGCGGCGAACTTCCTGATCTTCGTCCTCATCTACCTCACCGGACTCGCGATTTTCTGGGCCAAGTACCGCTGCGTAGCAGTCACCCAAGACGCCATCTACGTGTTGGAGAGCAGCAAGGTATCGGGCGGCGGCAAACCGCAACGCCTGATCGGCACGTTGCCACGCCGCACCCAGCTCGGCCCGATGTCCGGCCGATGGAGTCAGATGAAACTACTCGGCGAACAGTGCTGGGTCCACAAGCGATTTCACGATCAGGTCGCTGCCGCCGACCGGGAGGCTGGCTTCACTGCATAGACTGGCGACCGGCCAGCGCACCAACACGCGCACCGCCACCAACCGCGAATCACGCTGGCTATTCCCCGGCCGCCGCGCCGGCGAACCACTGCAACCCAGCACTCTCTCAACCCCGGTGCAGGCCCTCGGCCCCGTCCATCGCCGCCCACGCCGCCGCGATCCGCCGGCACGTCCTCGACACACCGGCCCCGATTGTCGCCACCGCACTCCGCTACCACCAAGTCACCACCGCCCGTCTCGCCGCCGGAGCAGGCACACCACCTGGTCCAACTACGCCCCGGCGACCACGGACGGTGAAAGTCGGACCCGTCCATCGTCGCTCCGGAGTGCCTTGGCCGCCCATACTTCAATGAAGAAGCACTTCGATGGCCTACGCCGCACCGGAGGGCACAGTGACGAACTACCTCGCCATCGTGAGTTCTATCGTCGCCTTGGTCGGAGTTTGGATAGGCGGCCGCTTGACTTTTCGTACCCAGGCGAAGGGCTGGAAGCAGGCGGAATCCCAACGGTGGCGCGACCTTCGCCAGGCCACATATGGAGACTTCCTCGCTGCGGTGCGCCGCTACCGAACATACGTGGGGCGCCACGAGACACCCTTCGAGCTCGCGCCCTACGCGGATGGCATCCGATTGTCGCCACGCCTGGACGAGCAGGGGATGGTTCACAAGCAAGCGCTCGACGCAGCGCTGGCGCAGGTCCAGTTCATCGCGCAACAGCAGGAGACTGCTAGCGCTGCTCGGACCCTTGTGAGCATGGCGCGAAGGACTGCGGTGGCAAAGACGATCTATGGATCGAAGACCGTTCCCACCCGCATCGACGACATGTTCTGGCATTCGGAGCTGGCCTTCGTCAACGCCATCCGCGCCGAACTCGGTCTGATCCCTCTCGTCCAAGACACCTACGACGACCCCATGAAGACCCTTGATCGAGAACTCTTTGACGCATACCGCTCGCAACAGGCCGGGACAGGCTCGAACTGATCAACCCAGGATCGTCCGTAACTCGGTGTGACACCGGTCGAGCGGTTGATCGTCAATACGCGAAAGTTGAATAGGCGCTCTCACCACTATTAAGAGCCGACACCACCAGCCCTGGCGGCCGGCGAGCGCGGTGAGGCGGCCACATGCATAGCGGCCGATGTTACTCTCCGAGCAGAACCGGTTCTTCGTCACCGGCGGATGGGGCGAGCCGATAAGCCCACTCATCGAGAATGAGGGTTTCATAGGATGACGATGGATGAAGGGAACTCTCGGGGACACCGCGATGTGCGCTATTTCCGTGGAGACGAGCAGCTCGTCACACGTTTGGACTGGGAATGCCTTCCCGACCATAGCTACCGCATCACCACCCAATCACCCGACGGCGAAAAAGTCCTGGTAGGACGCGACCTGTTCGATGCGGTCCAGCGGTTGCGGCTCGAGTTGGAGCCGTCTGGCTGGCGGCTGGCGGTGCAAGCCGCGCTGCGCGGGGCTTACGCCTCGGGCATGCTGCGCGACATGTATGGCGGGCGAAAAATGTATTTTTGCCGTATGGGCCGCCAGGTGGTGCGGGCCGAAATGATCGACATTCTAGAACCGGCGCAGCTGGATGACGTCGTGACCGTGGAAGAACAGCTGGAATTTCTTGATCGATGGAGGGACAGCATCAGGAAATGACTTCATGGTTGTCCCCGTCCGACCCGCGACCGTCGGGAACGTTGTGAGCGTGATTCCGCCGGCGCACCGGCGAAGAACGCACCAGCGACAGGAACGCCGAGGGCGCCCGGCCGGAACGGGCCCCTCTGGAAATCGGCGATCAGGCGGCTGACGGGCCCGCGTTCGTGCGGGACCGGACAACCTCCACCACATGGGCGACCGCCTGTCGAGGCCGACGCCGTTGCGCTGGGAGCCGTCGCGGTACCGGAACAACAACACGGTGCCGCCGTTTACGTCGTCGTCGCCGGCGATCGCCCGCTGGCTCGAAACGCCGCGCGGGCGTTATGGCGCACCGCTCGGCGCGATCCCGATGCCGTGCCATCCGGCTCGTGGTCGCGGGAACATCGGCGGGTGCGAACCCTGTCGGACCCATGCCCGGGTAGCCCAATTGGCAGGAGGCGGCTGGTCCAGAACCAGCACAGTGCGCGTTCGAATCACGCTCCGGGTACGCAGCACCCTCGTGGAACCTGCAACCCACGGGAAGGCGCCGCCCAGGCCGGCCGAAGACGGCCGGTGCTCGGGAGACCGTCGAACATGATGGGGTCGCGGCCGCTCCTCCGAAGGGAAGAGGCTCGATGCCGGCGCTTTCGGCCGGCACATGGGGAAATAGCTCAGGTGGCAGAGCACTGGTTTTGCAATCCAGAGGTCACCGGTTCGAATCCGGTTTTCTCCACGCAGGGGTGCATCCACTCAGCGGCTACGGCCTGCTGACGGATCGTGGTGACCAGACCGGACGACCCAGCGCCCTTTTCACGTCTGTGCACACCGGGCCAGGTGCGAGCGCTGCGGCTGGGACCCGCATCTCCCCTGCCCCGTTACCTTTTTGATCGCCCCCAGCCGGGGGCTGCTCGGTCGCTCGGCCCGGTATGACTTACCGCCCCTGTCGCACACATGATCCGGGGGGTGTTGTCGCCGGGCCGGGTGGCGTCGGCAAGACCGCTGATAGGGACCCGGCCACCCGATGCTGGGTAGGTCTCTCCGTAACGTGGCTGCCGGCAGTCCGACGCTCTGACCAGCGGCCGAGCCCATGGTGGACATCGTGGGAGGCAAAGCGTGGACAACGCGTACGGCGTGTTCCTCGGCCTGGACGTCGGCAAAACTGATCATCACGCGGTCGCGTTGAACCCGGAGGGCAAACGGCTGCACGACGCAGCCCTGCCGAACACCGAGGCCGGGCTGCGGAAACTGTTCGACAAGCTGGCCCGTCACGGCCAGATCCTGGCGGTGGTCGACCAGCCGGCCTCGATCGGCGCCCTGCCCGTCGCGGTTGCCCGAGCCTGCGGGCACCAGATCGCCTACCTGCCAGGCCTGGTCATGCGCCGACTCGCTGACCTGCACCCAGGAACGGCCAAGACCGACGCCCGTGACGCCTACGTGATCGCCGACGCCGCCCGGACCCTGCCGCACACGCTGCGCCGCGTCGACGCCGGCGACGACACTCTGGCCGAGCTGGAAATGCTGGTCGGCTACGACGACGACCTCGCCGGTGAGGTCACCCGCATCAGCAACCGGATCCGCGGTCTGCTCACCCAGATCCACCCGCCCCTGGAACGAGTCCTGGGCCCGAAAGTCCAGCACGCGGCCGTCCTGGACCTGTTATCGCGCTGCGGCGGCCCGACCGGGCTGCGCAAGGCCGGCCGGTCGAAACTCGTCGAGATCGCCAAGCCGCGGGCACCTCGCATGGGCGTCCGGCTCGTCGAACAAATCTTCACCGCTCTCGACGCGCAAACCGTGGTCGTTCCCGGCACCACCGCGGCCGAGACCATCCTGCCGAAGCTGGCCGAAAATCTGCGTGACCTGCTGAAACAACGAGACCAAGTCGCTGTCCAAGTCGAGGAGATGCTTGACGCTCACCCTCTTTCCTCGGTCCTGATCTCGATGCCCGGCGTCGGGGTCAGGACCGCAGCCCGGATCCTGCTCGAAGTCGGCGACGTCGCCGCGTTTCCCACCTCCGGACACCTGGCCGCCTACGCCGGCCTGGCACCGGTCACCCGCCGCTCGGGCACCAGCATCCGCGGCGAGCATCCACCCAAAGGCGGCAACAAGCAGCTCAAACGAGCGTTCTTCCTGTCCGCATTCGCTGCCCTGTCCGATCCACTCAGCCGGGCCTACTACGACCGGAAAAGAGCCGAAGGCAAGAAACACAACGCGGCCCTCATCTGCCTGGCCCGCCGCCGCGTCGACGTCCTGCACGCCATGCTCCGCACCTCAACGCCCTACCAGCACAAACCGGTAGAAAACCTTGCGCTCGCTGCTTGA

Protein sequences of DBSCAN-SWA_2

>NZ_LT827010|6501598:6545938|6525717_6525951_-|WP_043512409.1|DBSCAN-SWA
MSSQHRHVNRNYRPADDEYDPVRAEVERAGFTMNTFFRAVLRWVRNDPRRLAQFKALMVEVDAETPRGRPKKNAPQE
>NZ_LT827010|6501598:6545938|6521593_6521800_+|WP_014692941.1|DBSCAN-SWA
MPFDLYLKSANGTVAIRNAPDSDREFAESLVDLLRQGMPADEILTIEHNRGAISVPWGELRGVWIEDV
>NZ_LT827010|6501598:6545938|6539766_6540591_+|WP_014692977.1|transposase|DBSCAN-SWA
MERLPYRTDLSDARWALIEPVLTQWREARRGLGIRPPVHDLREIVNAILYVARTGMAWEYLPHDFPPAKTVYDYYAKWEADGTTARIHDLLRSWVREALGRDAEPSAAVLDAQSVKTSCNVRESEQGIDAAKKIKGRKRHIATDTLGLLLAVVVTAASVSDSAAGKGLLSTLAAEHPTVSKVWVDGGYQNTVLRHGAGLGIDVERVPRRAEKGFQVLARRWVVERTFGWLMQHRRLARDYEALPQRSATMVYWAMTNTIMLRLTGESTQTWQRL
>NZ_LT827010|6501598:6545938|6533813_6534962_+|WP_052311758.1|DBSCAN-SWA
MRALDAFLRADPQTWPRLAPALVARAGEQRLREVVDEAHGRLGGITGVIDTPDGLAIEGPQGQVLAWAETDEGGALSGLWIAGARRGRVRSGRRAELIGYAVPYVPMLWGAIGCWTARSVLGWAGLLLTTVAMYTFIRGLGALPVRPWWANHPLTLLFTLALASTARLPRLTAEGGADSLIVGVVLVVAVVALLVPARRHRWPESTERPLAVFPVDGDWYVLQGGGRLINHHATVPEQRGAVDLVRIGPQRGDASRLESYLAYGEPVVAPCAGRVVTAVDGIEDQAPGTIRFAPPYGNRVTIDNGSELVTVAHLKPGTVTVRLGDTVEAGQLIGAVGNSGNSSMPHLHLQADRAGVGLQLRFACINGSLYRGRRVRAPKRRP
>NZ_LT827010|6501598:6545938|6542350_6542965_+|WP_014692981.1|DBSCAN-SWA
MAYAAPEGTVTNYLAIVSSIVALVGVWIGGRLTFRTQAKGWKQAESQRWRDLRQATYGDFLAAVRRYRTYVGRHETPFELAPYADGIRLSPRLDEQGMVHKQALDAALAQVQFIAQQQETASAARTLVSMARRTAVAKTIYGSKTVPTRIDDMFWHSELAFVNAIRAELGLIPLVQDTYDDPMKTLDRELFDAYRSQQAGTGSN
>NZ_LT827010|6501598:6545938|6515767_6516499_-|WP_052311754.1|DBSCAN-SWA
MTAYSAQGPDPLVVFISQLGCGAEAWKPVLDHLGQLRAFTYTRPGIGSADPRSAPNPPLPHSRFADELAALLDSAGLSEPAVIVGHSFGGNIARMYAARYPHRVVGLVFVDASIPRQRINPADSRLVDGDGPDATEIDFLTGEVEILNATLPDVPAVVLQGDARLWPDLVSPVHADLWDTYQRILARQLGCPLILADSVGHQVPTDAPALTAIVIAAVAKAAANGSAVHLDATKFGQAGGVML
>NZ_LT827010|6501598:6545938|6526686_6526902_+|WP_014692961.1|DBSCAN-SWA
MSVRQVNRDTVLAAIRSGARSLDDIAAHFQVLSHSPTLRQVLDSLLNEGLIYDGPDGLHAHGEQLTIDEEN
>NZ_LT827010|6501598:6545938|6505351_6505705_+|WP_080128258.1|DBSCAN-SWA
MFGGHPDLMEMLDDAERGNVFLLLPTVAVAEAEAALNVGLALWTPFLMSRGVTTLDLTMHTAVEAARLADPQLPGAVAGPLMAGQVAFEAQALNAVVVTQMPSMYAGYEVAIMPVEA
>NZ_LT827010|6501598:6545938|6519026_6519896_-|WP_014692935.1|DBSCAN-SWA
MQDRELKKWLLQPGGVVERLRQLQSTGTTKTSNNDLAARAGWIPSKVSKLRLGQQTPTADDIRSWVAATGGSEQDEHELLVMLADAERHTTSFQKALKKGQAAHQQTYNELVEQADVVRMIERSFVPSVMQTREYATAVLTGSMKLHKTADDVAEAVAARMQRRKFLLDEKYRFEFIIDETVLTRRVAPPEVMYSQVDRILEYMDLPNVRLGILPVYGTFHDVVRNSFELYGKIGVVETYYDDDELDADGWTAHANAMRDVWQDAVEGDEARKLLRAAMKYHASDMNKS
>NZ_LT827010|6501598:6545938|6523142_6523361_+|WP_014692948.1|DBSCAN-SWA
MIRIRLVDGRTVETNTYTLDQAYKLMADGHPLQIGGPEDCELQPVFADDPQGENPRQAINAAAIVSIEEDGA
>NZ_LT827010|6501598:6545938|6536364_6537273_-|WP_157432809.1|DBSCAN-SWA
MLAAGCSGSSAEADELVIATGSVGGVYDRLGTALASVGQRFALQMSAVRTAASIENMTLLGNRAADIGFTTVDCASLALGGEAPFPAPVPIAALAALYDDYLQLVVRADASIGTLADLAGRRVSTGEVGSGTDIAAERVLAAAGLAGRVRIARQSLSTAVAGVRAGALDAFFFSAGLPTPAINDLVRAEPGIIRLLPLSQLVGRLQSEFGEVYAERTVPRVTYRMTADVGTIGITNVLVVRRDMSDNVARRLTALLFEAGFQLRDAHIDAEQIDPRSALGTYPVPLHPGAQQYYRAAKLFVD
>NZ_LT827010|6501598:6545938|6529964_6530237_+|WP_155123667.1|DBSCAN-SWA
MGLDQAAMASPAPEAVKPASVAPIVAFNGSADPQFWGAVAQAAANAAAGAVAAAVVAAALAPKSSSSSSGGPATGTAADRSGDAQFDVAS
>NZ_LT827010|6501598:6545938|6517952_6518297_+|WP_014692934.1|DBSCAN-SWA
MDSDSIGDVIEVSTATGTEQEALELAKQAVKARLAAGAQISGPAKSVFWHLGEFGVGEEWRLVLRTHASRFEPLKAMLVERHPWKNPEVLALRVAAGSSEYLVWITSTVGGAAD
>NZ_LT827010|6501598:6545938|6518463_6519018_-|WP_155123665.1|DBSCAN-SWA
MRKVLTDGGPGTEFWRAFETFKRSAWRWEQQPAYHLGYEQAQFDQFLAGHPESPLENEELGSWMKQVAAHVNHGRTIGRVRIVETPPTDYQRWMRWMDKFNRGAGETIQYLTRHGAQKAGIIPGIGAEDWWLFDDRRLLLMRHDDKGRRVRVEAVEDEPEVEKAIWWRAQAIAAANREAASLEV
>NZ_LT827010|6501598:6545938|6527192_6527450_+|WP_014692963.1|DBSCAN-SWA
MTTLRDDLAVLIREADKDNELSPYQLASSISEFLLDRGLVTPVQAHAVSDFAEEQNRGAGYRHPKPVGPEALAAVIVDRFNLEEN
>NZ_LT827010|6501598:6545938|6530341_6532120_+|WP_014692969.1|DBSCAN-SWA
MRAIALLAAAAAIVMSVGNTFPAAAETAGSAVARLYIDVRDQNDLDSLARAVTDPRSPSYRHFLSPADYRRRFALTDAQHRDLLTRLAADGIRVTGETSHYLRITGPAAAVARVAGASAAAHSLSTPVSAAADAAARLAGPQARVREKADADEPAKCSSWLGESPAADMPPAYGSISSYATCPYRPDQLRKAYHVTTTGRGRTVAIVGAYGSPTMRADADRFATAVGDKPFRPGQYREDVDPNAWNLTPDCAPPADWAGEQALDVETVHGYAPDAAVRYVGANSCLDEDLMDAESSIIDNRSADLITNSWAEIIHADPGHLTPDLVAAWNRLFEQAAVEGIGVYFASGDCGDASPGAAHAGLNCDPATTAAQAEWPAASPWVTAVGGTALGTDAHGRYAWETSMGDDLSIRSADGTAWTPLPGVFVFGGGGGPGDAPQPWYQRGVVPAALAAAGGQARRVTPDVALEGDFAVPVLVGYTLGGTFQLIGYAGTSAASPGFAAIQAGAEQVSGRTIGFANPLLYRLSRAGVLHDVTEPTAPVTAVRDLGADQGDLRYVLFTLGQDYGLSATTGYDAATGLGSPGPAYLSWFRRH
>NZ_LT827010|6501598:6545938|6521796_6522048_+|WP_014692942.1|DBSCAN-SWA
MNVFSYRLVYRGKVEAEGVNSDFQHDNAEDFGRAYAATIDANRPPRPYPLHLLVWEGEDTSRDPDFKHRCRRHVDHVLTGVAS
>NZ_LT827010|6501598:6545938|6543211_6543640_+|WP_155123669.1|DBSCAN-SWA
MTMDEGNSRGHRDVRYFRGDEQLVTRLDWECLPDHSYRITTQSPDGEKVLVGRDLFDAVQRLRLELEPSGWRLAVQAALRGAYASGMLRDMYGGRKMYFCRMGRQVVRAEMIDILEPAQLDDVVTVEEQLEFLDRWRDSIRK
>NZ_LT827010|6501598:6545938|6541568_6541985_+|WP_155123668.1|DBSCAN-SWA
MTRRPDPMARRQSQPRADLVHRSAPFLPSDSEIRQVFIYQTAANFLIFVLIYLTGLAIFWAKYRCVAVTQDAIYVLESSKVSGGGKPQRLIGTLPRRTQLGPMSGRWSQMKLLGEQCWVHKRFHDQVAAADREAGFTA
>NZ_LT827010|6501598:6545938|6526210_6526690_+|WP_014692960.1|DBSCAN-SWA
MTTMEDLYPDGHGYHDAHGPYIDAVAKALDEAGFKTDISWSDPNDPRDGWIGFDMEQQPHRNGEPVWSYDEVGIGWSENRGWHLLCIDDRNGRDSRYVFELAIARLASPETVANAVAEQAGIDAHVASDDYPDVDFPEHTFEDDDIPFDQALAQYREPA
>NZ_LT827010|6501598:6545938|6523357_6523621_+|WP_014692949.1|DBSCAN-SWA
MTARILTLKPSQMQRLRQQQHVWWDDSTGREVLVRTDPGGRVDTYPGALVLTLTPADLDLIETPDGLVCADETRTTGWTVCMAEVQA
>NZ_LT827010|6501598:6545938|6520860_6521070_+|WP_014692939.1|DBSCAN-SWA
MRTTHPLTADRAALAAAGPQAFALTPDDEREIGNFLIEVDSLPDEDAALRLRIPIDMVPQFRQLMATGR
>NZ_LT827010|6501598:6545938|6522375_6522600_+|WP_014692945.1|DBSCAN-SWA
MSTVYVAEIEGQDLRLIKDGNPNVPYDLEVYPIYGHDDADRWLAKHGYTDHDNWGWRKANSSKPAIWLKNVVAP
>NZ_LT827010|6501598:6545938|6540712_6541529_+|WP_085945656.1|transposase|DBSCAN-SWA
MSKAWVIDDELWKLIEPVLPAWPARAPGPRPVPDRLCLQGILFVLHTGIGWEDLPQELGFGSGMTCWRRLQRWAEAGVFDQVHQILLDKLNAANRIDWSRAAIDASHIDAKKGGAGTGPSPVNRGKPGSKHHLICDGNGTPIYVLTSGANVPDIKRALDLLDCYPPIAGRLGRPRRRFAALLADKAYSSAAFRQACRERGTEPLIPKPKTTGIKGLGKLRYVVEQTFALLHQFRRLAVRWERRLDIHDGFVSLACVLICWRRLINWTDQRSC
>NZ_LT827010|6501598:6545938|6528068_6528290_+|WP_014692966.1|DBSCAN-SWA
MTVTVTDMHIPAQRDPGHDQMVTPESARVAELQEMIRSGQYAGYLDELTDALAKAKAARDEIRQLTATSALGA
>NZ_LT827010|6501598:6545938|6511006_6515038_-|WP_014692930.1|DBSCAN-SWA
MNGNISSSSHFQQGDDNTQNFYYFISYGADGEAVRPEAMLGHVRELTPATLEDRDEELAELAEFCFGDEPYMRWEGEPWAGKTALLGFFVLHPPERVDVLHFFIRGGQASWNDSFAFEQVLRAQLQAYLATTDPGTVNPSLLHLDRTDLLDRAVKHAAATGRRLALVVDGIDEDQSRSRATRLPSILSLLPADPSPVLRVILASRHQLDQPTDVVDHPALSCRVRRLSGSARAARLQRAARLELDTLLGMGSLATDVLGFAVASEGGLSIAEVAELSGAEAEKVRETLVNGAGRTLVLTAFPDGGTGFAFSHDSLRLGASEVLGASKMRQYRARIDDWARAYRSLRWPAETPFFLLARYGKRLADAGEVGPLTELARDTSRHARMRDELGGDGPALTEVVSAQALWQLQRDPDLRSAAQLARIRWELTSPNLHMPPELPAVWALLGQPGRGLNLIDALERSPQRTELQQSMIDALLHAGRPDIAAYVASDLPDPEREVALHSVATALLAAGQTDEADGVIGFAAEKCANGIEVVIRYARLRGATYARQFRHPGVREAAFYQVIEGLCEDGRISEAQEVAAEIRDAQVRGLADLTIADAAGHPISPTLHRRVLELAAENPHLSETILATLARCLARAGSYQEAETALLRTADPADAGRPVLAICVEAGSFADAEALAARLARAAHRLSPVNDLCDLLVDADRPDRALALARTLPTAAEQVGRVAAVGARLMSRGDPRGPGVLEEAERLASETGPKGYAHLAILAARMADDALMTRSLRRVPDDALVSVASAIAEGGWESAAMQAVDLLDDPVQEAYVALQLAEAAIEQNRPQVARRAALFAVERRLTGTDFDVDEPDFDATEVDPLDLDEAGVILARAARILATVGDVRAALRVATAADTASRQTTDPERADEDLALVACAEAELGDLEGAEKRIRRIGDKETRREALSQLARLATGKPRADTEASDEDGTGELAARLAEELQGDILQEVTAALVASQRLRLASRLAGRAAEPGERAHALAVVAQGYLEVRDADHADLLAIHALRILPTGESVEHSETAACIATVFLAAGHADRIPAVEQQLRLAWQRAVFHAELAVQTIAGGTLTPDAAVRYIRRAEQIAEALVDPWERCCAFSRLITAWSAVGDAPSVTRMIAAATEAAVGCDGSWMLPEPVVLGIDALLRLDRPEEAARLLQDDAEHTPAMEVYLAEALAEHGHLDAALHFARSLAPERAFTQRWNVFTSGPGGDDVRDQALARIVAVMARDGGRPDDALRIVEEITSPWAKAGAMTDLAVGLARGRRPIRAKQVMAAALALGEWTIPLRGLVVVEPDAIRAAVSQRVIDL
>NZ_LT827010|6501598:6545938|6504875_6505310_+|WP_014692926.1|DBSCAN-SWA
MNEPPHEGPDDWYFDEKLQRWLRHSGRAYWRQFLAERRERAATCELQTGREFQQQAFSKRIDLVQDDDSSLRPAKVVGMDSDAPIPADETGRPPRASERLMALLGRSAPAPMTPEQRAGYQARMDRADADLREIIERRNTPSAA
>NZ_LT827010|6501598:6545938|6522044_6522209_+|WP_014692943.1|DBSCAN-SWA
MTATIRRLLGRANRPANPFDLGVRVETGENEWHGQVPTGVTVILLGDPSRAVAR
>NZ_LT827010|6501598:6545938|6507218_6510545_-|WP_014692929.1|DBSCAN-SWA
MTRRRRIWVISSVVVFTVVLTTVVSVRATLNTASTLWGVISALVAFGSTVAGMKLLKPDVTPSDGAELEAALVADVRRQLQEEERRQRLNDPWPIPVQLRPADAAITDHWQVIRAGDGDGTPLPLTGNLSQIDTLFSAIPSGRMVLIGPAGCGKTVAARRLAVLRADAWQSGQPVPVLLSLAAWNVTRQPLPQWLVQQIADDHPAVPQARTVARTLLVAGRLLVILDGFDELLPQARRQALHEINQSLSAPQLLVITSRADEYTAEVTASDVLTAAAVLRLQPVPLATAFTFLQEAGPPTTAARWRDVQARVTERDPLALVLRTPLFVTMARALYDTAAANPAELLDRARLPDRAALERTLLGQYVDQAARSIAADSGGVISPRRVATVHRHLRTLAAIVRTGRTGDLSWWQTPHVVPAVAAAAPISMTLGLLGAVSFAVVLGGKWQVACTSLFATLAGVFVAVTVGAITLPPRPTAGGRYVEKPHWMRAIPVPALVAGAGAVSLLAAAVGGVAAVYGARTLVVDLTGLLFVVFATVWLLSPSWADLRYTDWDRRRERWLGTALAFTCGGAVFVAGAVEGQVSPGRVYQFAVLAGFAVAAAVSGIIAGRRPRVRSRHRRHRASRRRVMLSWLVAVTVAALLTAVDPFLWWGAVQAAVVALALRLLGETLVSIGPGYRTPRRVAPRLGDAAPVIVPRVGLGAIAGAIAVTVMTLLFPALSWPVWWAAGISTGDLPVPALPALADMAPFVFVGALTGLLVGVLHWVLAPIDHGRMAGPRQALHTDATVLGLLLAVPAAVAGTLAAVLVGQHPHRPALVFVCAVLLIMLPVLVAVVRTSAWLQYRTAHLWLAGTGRLPWRFLRLLEQARDAGVLRQTGSTHRFRHVRLLHQLHVPATNVTGSRRRAWPPEEWPAAWRWSAGAAVCLLIAGGAVRQADIVAAAEQTQPTLATPTWQDLQRHGACLPGCRVTGHVAVNHKSWGPVTLLSTLDESGDEPIAGVVVTDRTGKVRWQQELDTWTELTIAGRDRTGNVFLIFSMGGDKGVVVLHPVRRGFAELGPSPEDPYFFSSNLIDAGDGSYAIDQSINDCSPPCADGAVTHTRYYWTGKSYRP
>NZ_LT827010|6501598:6545938|6520582_6520858_+|WP_014692938.1|DBSCAN-SWA
MHTAPATYPYSTAQDMLLGAGLTEKQTVSVISRLSEDGVRVLAASASEPARQVVHALAHETIAGLAETLHMQADPDVAVVRELLRHAVGAW
>NZ_LT827010|6501598:6545938|6505910_6506807_+|WP_014692928.1|DBSCAN-SWA
MAGPEFEGQEERREANRPRDDWPAIVEAVKTPLGFFALVVLAVEGILAVGVGLTSGPNQTYLVLGMIGLVASLILLVTGMAVWRPESLYGKTPEIVVSIAKAPAGSGSPDTQDGGVAEVVENPKFLIAGSEAAPWDRFLEEDRGIITAAFPGSTVSVEPAETAAGFSQALLTLGAHAQVWQLSAQVEGSGSIQIGSDSLPPRGLGEVVRQSRPKLVVLAACASASVAAEIAPSAATGTLDSDAWKRWSTIFYTLLATGVPLSRAFAITQAVDGLPVAMILRRDMIFAGRDQRSLRAGK
>NZ_LT827010|6501598:6545938|6503908_6504304_+|WP_080128064.1|DBSCAN-SWA
MSTATDIAAALREQAQAQIPYGLSSNLTDVQYDAARFAVASFGALSAMDLEALVRGQGPWTATPTGKAIDITVIRDTVRAQQEIPEGNVSGYPQSLRQAMLRPADQRPPRAATPDSPEEIEAFIADVKARM
>NZ_LT827010|6501598:6545938|6527853_6528072_+|WP_014692965.1|DBSCAN-SWA
MTDTAAVPLKDVVHVLRLARDGQLGGTNDWTTEGFVSAVWNGFITKDDTMGLTPAGEAFLGKVGVLFPEATR
>NZ_LT827010|6501598:6545938|6520066_6520294_-|WP_014692937.1|DBSCAN-SWA
MQDFNIEFLWKDVASGGNGCHAILKTDGGYYVQGRVVTGDERAAVLSHSEANRSGLLDDEDVIFVHGNVLDRLNS
>NZ_LT827010|6501598:6545938|6526052_6526211_+|WP_014692959.1|DBSCAN-SWA
MPDTDLTARLHRLLHLYRALPDDRIVLAAIVGDDADTLTLGDLRELARLVGA
>NZ_LT827010|6501598:6545938|6526903_6527131_+|WP_014692962.1|DBSCAN-SWA
MSLIGGRIRDLIYVEKEHVNLDEAAAIARVLRCTGKYGAGRPEVRTDEMVTDVLAVMQVLAGPDGDNARYLSRSA
>NZ_LT827010|6501598:6545938|6532145_6532808_+|WP_014692970.1|DBSCAN-SWA
MSPREALPVRIRVAVPLLLLVVALFTAATLIYNAPASPARNRLDFVPKLLQPYFWQDWQLFGPNPPVTNNLIYLEVRLRDATGQVTESAPAEIEQAIDRQPRSFRTNPTKTPGIMLAFNASANNFARAASAIAKMPADQQADARKKLFDEYANFFVEMQRFFSASADGLYPGRDIVAVRARFRTRSIVPFSQRYQDPPPAQPEKELLDTSWLTYIPGIAR
>NZ_LT827010|6501598:6545938|6534958_6536395_+|WP_014692973.1|DBSCAN-SWA
MIDVIVVGSGPNGLAGAVALARQGLTVTVLEAAETIGGGTRSGELTVPGVLHDHCSAVHPMAVASPFLASLPLDQHGLTWTWAPVELAHPLDGGRGAALYRSIERTAAALGDDGATWRRLFGPLAADFDTLATDLLGPVLRVPRHPVRLGRFGLRAAAPASALARLWRTAESRALFAGTAAHAMRPLHTPGSTAIGAMLIAAGHRHGWPVARGGSRAITDALARHLFELGGTIQTGALVRSLADLPPARVVLLDVAPSAAARICGDRLPPRVARAYRRWRHGPAAFKVDLAVEGGVPWRLEAARQAGTVHVGGELNEIAYAERQVTDGRLPTRPFVLVAQQYLADPARSQGDIHPVYAYAHVPSGWDGDATDAVLDQIERFAPGLRERIVARSVHTVSQFSGGNPNYVRGDILTGANTPAQLVARPRWAIDPYATGVPGVFLCSAATPPGAGVHGMCGYQAARSALRHIQSTKSLAAR
>NZ_LT827010|6501598:6545938|6523802_6523994_+|WP_155123666.1|DBSCAN-SWA
MTAYDPGRSIGGERCSRIVSNEMIDAHPDWSDQQIADRLNRRFDNPVITVDEVAHWRSERATA
>NZ_LT827010|6501598:6545938|6537311_6538697_-|WP_080128068.1|DBSCAN-SWA
MRNRLMSCYSVLLAAVLTGLIVPLAISTVTRDTQAMFIDRLNDTDRLASLADPALRTGHITALSMELRQYHQIYGVDVLLVDRDGVTVLEQGDGQVASRAMLRRYVDEALTGERHDVSGAIWPWRDQPLVVATPIGRGGEIIGGILTISPVRGLQLEVWRYLAVLAACGVLAMIAGIAVGQPLVRWILRPVYDLDAMVTSLPEQLHRSRAAESGPPELQRLAASVNQMADRITELIDRQGSFVSYAGHQLRTPLASLRIALDNLAPAPGKRDRSHEIAVQEADRSAAIIDSLLAYASANARAAAATEIDAVPAIEAWVAARQPMAEAARVQLVCRAAGPRWVRVAPSVLDQAVEVLVDNAVKYGETRTRIFIEVAAPEPGWVEVSVEDDGVGIPDDELLHAVEPFWRHPSRQVHDGSGLGLSIIGALVTASGGELQLAGVRPHGLRATVRLPAARTECDAR
>NZ_LT827010|6501598:6545938|6515034_6515457_-|WP_014692931.1|DBSCAN-SWA
MDLDELSAAVMPYVSAAVAAYGGAMAQRATDAAVDSGSTATVAWGRQLLARLVASRRGRQVTEAVEELARDPADDASRVLLQAQVLKAVSIDAHLAAELEHIVQEARADGDHYTVSVHHSSGFQIGSNNQQNVFMRPSTE
>NZ_LT827010|6501598:6545938|6523617_6523806_+|WP_014692950.1|DBSCAN-SWA
MSIDYTGEVVGRDPVGKTIVEALVSSHPDWSDQQVTDRINREYDEPVITVAEVARWRPGMAR
>NZ_LT827010|6501598:6545938|6544732_6545938_+|WP_014692983.1|transposase|DBSCAN-SWA
MDNAYGVFLGLDVGKTDHHAVALNPEGKRLHDAALPNTEAGLRKLFDKLARHGQILAVVDQPASIGALPVAVARACGHQIAYLPGLVMRRLADLHPGTAKTDARDAYVIADAARTLPHTLRRVDAGDDTLAELEMLVGYDDDLAGEVTRISNRIRGLLTQIHPPLERVLGPKVQHAAVLDLLSRCGGPTGLRKAGRSKLVEIAKPRAPRMGVRLVEQIFTALDAQTVVVPGTTAAETILPKLAENLRDLLKQRDQVAVQVEEMLDAHPLSSVLISMPGVGVRTAARILLEVGDVAAFPTSGHLAAYAGLAPVTRRSGTSIRGEHPPKGGNKQLKRAFFLSAFAALSDPLSRAYYDRKRAEGKKHNAALICLARRRVDVLHAMLRTSTPYQHKPVENLALAA
>NZ_LT827010|6501598:6545938|6532804_6533806_+|WP_014692971.1|DBSCAN-SWA
MNRLDTFLARISVREHRLIGIALMRIVIGFATILYCLADYDRREFLWGPTSYYSAGVARTALPHHGFSLFLLSDSRVWFEIVFHLVIVVSLAFMIFGGRSLTIAQAVLLWSLHWRNQDVLEGGDNLAQIVIIFMIFTVSNAYFAPGARNRRERMLAREAPVLRTAVHNLAAYLMVFQICVLYFMAGYWKVTGEQWQDGVAMYYISHVTGFALSSTYAALMSNAFIGTAVTYFTVFTELAFPFAVLSVRGWVRKTVILAIEGMHLGIMVFMGLVCFGLLMLGADSVCLRDDDYKTMYRYALRLRDATLARYRRRFTAPVPSAVVAMEEDTRVAA
>NZ_LT827010|6501598:6545938|6527452_6527857_+|WP_014692964.1|DBSCAN-SWA
MSFHPPADGRWAMQPRLFRIGNTTLLDDDPNPWTVKAVTANFAVLTRLDDPEWENGDDDPEDGPTSNDCDVLYTVLDCRNGYRGPCNLSGWGYGDGTYSEADCAAMLADFEAGDLEISHRNWTRIRFADEAAVR
>NZ_LT827010|6501598:6545938|6516534_6517773_-|WP_155123751.1|transposase|DBSCAN-SWA
MNTIEARFARPEPRRRVRDFVAGLLAPLPTKNCWTIAEHAGDDGPGGMQDLISRASWDDALVRADVRDFVAARLGHPDGVLLVDETGDLKKGTHTVGVQRQYSGTAGKIENCQLAVHLSYASPLGHSLVDVALYLPKSWIDDPQRRAEAGVPGAVTFATKPELARRLIETAVAGGLPCRWVAGDEAYGGDPQLATALRRHQLGYVLAVACSHRAPTGLGVQRADQIAAGLPKHAWQRISAGNGAKGHRYYDWAFITLPHAADPHQGHHWLLIRRNRTTGELAFYRCWSPQLVALHHLVAVAGRRWSIEESFQATKSGLGLDQHQHRRWKAWHRWTTLVIAAHAFLAAATTASTTSPDGLIVITVNELRRLFHALVIEPGRRVVDVIAWSIYRRRHQSAARTSHYARQALTEP
>NZ_LT827010|6501598:6545938|6521152_6521347_+|WP_014692940.1|DBSCAN-SWA
MSTTTYAPPAGADNPDDFDRWEKELVGDTRHHFRPSKAALRREDQHAIDEALGYHRHRTNERRD
>NZ_LT827010|6501598:6545938|6522596_6522782_+|WP_014692946.1|DBSCAN-SWA
MTDLNALLTLYTTWSKALEAAEKDGPEQSAIRAEIADYEAAKAARQIADLLAAEILEPASV
>NZ_LT827010|6501598:6545938|6538699_6539368_-|WP_014692976.1|DBSCAN-SWA
MRMLLVDDDTRFAEVLIVALGKIGYQLDHVERAGDAVAVSAYDAVLLDLNLPDLDGLDVCRRIRQHSNVPIIILTARGALGDKVIGLRRGADDYLIKPFSVMELQARLEAVLRRGRPLLPAAQTLGDLTLDPDRHRATVDGCEIELTRKEFHLLGVLAEAPGSVLRKNQLMVRVWQAADPSAARTLEVHISSLRTKLRRAVTIETVRGVGYRLVPRGDGNAG
>NZ_LT827010|6501598:6545938|6522865_6523123_+|WP_014692947.1|DBSCAN-SWA
MQHIHTNAAELMSARNGTTTFMTVADGTYSNKVAFDVKGGEMAPTDGLPRVVLTPDQFQKITAKDSRDYQVTADDGSVYAVSVWA
>NZ_LT827010|6501598:6545938|6523990_6524215_+|WP_014692952.1|DBSCAN-SWA
MSAYANDPRVNDVTGRGTLFLVADKPDGEPVARVRPFIDGATWVAWPVDENLMTELPEFGTADEAIRSVIGDPQ
>NZ_LT827010|6501598:6545938|6501598_6502825_+|WP_155123750.1|transposase|DBSCAN-SWA
MDAELVGRLVEQARAAGLQLTGEGGLLQQLTKRVIEAALDGEITDHLGYEKHDPVGKDGGNSRNGTRAKTVLTDVGPVEITVPRDRDGSFEPQIVKKRQRRLTGVEDMVLSLSAKGLTTGEISAHLAEVYGADVSRQTISTITDKVMDGMAEWQNRPLDRVYPVVFLDAINAKIRDGKVANRPIYVALAVTVEGTRDILGLWAGDGGEGAKFWFSVCTELKNRGVEDVLMAVCDGLTGLPDAINTVWPRTVVQTCVVHLLRNSFKYAGRQHYDAIAKALRPVYTAPTEAAAEHRFLEFAEAWGGRYPAIVRLWENAWAEFVPFLAFDAEIRKVVCSTNAIESVNARIRRAVRARGHFPNEQAALKCVYLAVMSLDPTGTGRRRWAIRWKPALNAFDLAFEGRLTAGRN
>NZ_LT827010|6501598:6545938|6524211_6524436_+|WP_043512408.1|DBSCAN-SWA
MTTVMCQNPLCQYTSEAVHELRVAGTKMVRLVCADRSCTFWASGELCKDVPNAVIERDELHPVDAGGVHIYDDF
>NZ_LT827010|6501598:6545938|6524628_6524811_+|WP_014692955.1|DBSCAN-SWA
MADLPADLLVIVHHDDSVTRYEQVTYCPWPGGVTVYRNGEQIAEHNDVIGQHAERAAVPA
>NZ_LT827010|6501598:6545938|6528527_6529421_+|WP_014692967.1|transposase|DBSCAN-SWA
MATLAVTRRHDLTDRQWAVLAPLLPAASTTGRPPKWDKRQLIDGIRWRIRMGTPWRDVPAVYPPWQTVYGLFRRWQRDGTWDRILAALQAAADTNGRIIWTVSVDSMTSRAHQHAAGARTNGHLQKEPPGGVHDEPADHALGRSHGGLTTKTHLACEQGQKVLSMVVTAGHRGDSPQFIPVLRRIRVTRLGVGRPRTCPDLVLADKAYTSRANRAYLRKRGIKACIPSKKDQDAHRKAKGSRGGRPPKFDKALYRMRHAVENSIARLKRYRGIATRYEKLAVRFQAALTIVIIGEWL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_155123750.1|6501598_6502825_+|transposase	IS256 family transposase	NA	NA	NA	NA
WP_080128064.1|6503908_6504304_+	hypothetical protein	NA	NA	NA	NA
WP_014692926.1|6504875_6505310_+	hypothetical protein	NA	NA	NA	NA
WP_080128258.1|6505351_6505705_+	hypothetical protein	NA	NA	NA	NA
WP_014692928.1|6505910_6506807_+	hypothetical protein	NA	NA	NA	NA
WP_014692929.1|6507218_6510545_-	NACHT domain-containing protein	NA	NA	NA	NA
WP_014692930.1|6511006_6515038_-	hypothetical protein	NA	NA	NA	NA
WP_014692931.1|6515034_6515457_-	hypothetical protein	NA	NA	NA	NA
WP_052311754.1|6515767_6516499_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_155123751.1|6516534_6517773_-|transposase	IS701 family transposase	NA	NA	NA	NA
WP_014692934.1|6517952_6518297_+	divalent-cation tolerance protein CutA	NA	NA	NA	NA
WP_155123665.1|6518463_6519018_-	hypothetical protein	NA	NA	NA	NA
WP_014692935.1|6519026_6519896_-	hypothetical protein	NA	NA	NA	NA
WP_014692937.1|6520066_6520294_-	hypothetical protein	NA	NA	NA	NA
WP_014692938.1|6520582_6520858_+	hypothetical protein	NA	NA	NA	NA
WP_014692939.1|6520860_6521070_+	hypothetical protein	NA	NA	NA	NA
WP_014692940.1|6521152_6521347_+	hypothetical protein	NA	NA	NA	NA
WP_014692941.1|6521593_6521800_+	hypothetical protein	NA	NA	NA	NA
WP_014692942.1|6521796_6522048_+	hypothetical protein	NA	NA	NA	NA
WP_014692943.1|6522044_6522209_+	hypothetical protein	NA	NA	NA	NA
WP_014692945.1|6522375_6522600_+	hypothetical protein	NA	NA	NA	NA
WP_014692946.1|6522596_6522782_+	hypothetical protein	NA	NA	NA	NA
WP_014692947.1|6522865_6523123_+	hypothetical protein	NA	NA	NA	NA
WP_014692948.1|6523142_6523361_+	hypothetical protein	NA	NA	NA	NA
WP_014692949.1|6523357_6523621_+	hypothetical protein	NA	NA	NA	NA
WP_014692950.1|6523617_6523806_+	hypothetical protein	NA	NA	NA	NA
WP_155123666.1|6523802_6523994_+	hypothetical protein	NA	NA	NA	NA
WP_014692952.1|6523990_6524215_+	hypothetical protein	NA	NA	NA	NA
WP_043512408.1|6524211_6524436_+	hypothetical protein	NA	NA	NA	NA
WP_014692955.1|6524628_6524811_+	hypothetical protein	NA	NA	NA	NA
WP_043512409.1|6525717_6525951_-	hypothetical protein	NA	NA	NA	NA
WP_014692959.1|6526052_6526211_+	hypothetical protein	NA	NA	NA	NA
WP_014692960.1|6526210_6526690_+	hypothetical protein	NA	NA	NA	NA
WP_014692961.1|6526686_6526902_+	hypothetical protein	NA	NA	NA	NA
WP_014692962.1|6526903_6527131_+	hypothetical protein	NA	NA	NA	NA
WP_014692963.1|6527192_6527450_+	hypothetical protein	NA	NA	NA	NA
WP_014692964.1|6527452_6527857_+	hypothetical protein	NA	NA	NA	NA
WP_014692965.1|6527853_6528072_+	hypothetical protein	NA	NA	NA	NA
WP_014692966.1|6528068_6528290_+	hypothetical protein	NA	NA	NA	NA
WP_014692967.1|6528527_6529421_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_155123667.1|6529964_6530237_+	hypothetical protein	NA	NA	NA	NA
WP_014692969.1|6530341_6532120_+	peptidase S53 propeptide	NA	NA	NA	NA
WP_014692970.1|6532145_6532808_+	hypothetical protein	NA	NA	NA	NA
WP_014692971.1|6532804_6533806_+	HTTM domain-containing protein	NA	NA	NA	NA
WP_052311758.1|6533813_6534962_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_014692973.1|6534958_6536395_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_157432809.1|6536364_6537273_-	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_080128068.1|6537311_6538697_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_014692976.1|6538699_6539368_-	response regulator transcription factor	NA	NA	NA	NA
WP_014692977.1|6539766_6540591_+|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.8e-06	28.2
WP_085945656.1|6540712_6541529_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_155123668.1|6541568_6541985_+	hypothetical protein	NA	NA	NA	NA
WP_014692981.1|6542350_6542965_+	hypothetical protein	NA	NA	NA	NA
WP_155123669.1|6543211_6543640_+	hypothetical protein	NA	NA	NA	NA
WP_014692983.1|6544732_6545938_+|transposase	IS110 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_LT827010|6859610:6922095|DBSCAN-SWA
CTCATAGCCCGAATCTCCTTCCGCCCAGCGGCGTGGGCGTTCCATCGATGAGCACCACCGGGCTGCCGTCCCGGTGCGTCGCGGCCGTGTCGATCGCCAGGCGCTTTTCTGCGATGGCCCGTACGGTCCAGCGCAGCGCCACCTGATCGCTCGCCGCTTTCTGCCGCATCTCCTGCTCGTGCGCCTCGGCCGCCGTGGGACGACGATCTTCCACGGGTACCGACGGCCCGAGGCAGAGCACGGCGCCGCCGTCGCGGGTGCCGTCGACCAGGAAGCACGAGGTACGCGTCGACCGATGTCCGAGTTTCATGGCCAGGCGCACCGGGTCCTTGCCGATCAACAACCGCTCGCCGGCGGAGCCGAGCAGACTCAGATCCCCGGGATGCTGATTGATCATGCGGCCGGCGAAACGCTGAAGCAGATCGCCCTCGATCCATCGGTGGTAAGCCAGGACGATCAGGTCCAGGCGTCCGTGGACGGCCTCCCATGCGCCGATGCGTGCGTTCAGCCGGTCATGCCACTCCCGTGCGCGAGTGCGGTACCGCGCACGGTCCGCGTCGGTGCTCGCCTGGGAGGACAGCCCACAGTAGTCGTCGAAGTCGCCGGGCCACGCCGGTACTCCGGCGCTGCGGGCAACGTCGATGGCGGGCACCCCTGGCGCGTGTGATGCGACCAGCGCCACCTCGTACGTATCCGGGTCAGCCGCCGCCATGTCCAGCAAGGTGCGCAGATTGGCGCCGGTCGCCGAGACCAGCACCCCGATCCGGAGCGGAGTCGTCGCCTGATCCAACCCGACCGTACGAACCGTCACGGCATCGGTCACCGCGGATTCCCTGTCGACAACTCGGCGCCGGTCAGCAAGGCCATGGTCACATCGCTACCGCCTCGCTGCGGGTTGACCAGGTGCATGTGCCGGGCCCCCGCGACCAGGTGGTGGGTCACCGGCAGACCGTCGTGCCGCCACCGGGCGACCTGACGGTCCATCAGCGCGGACGGGACCGCTTGATCGTTCTCGGCCTGAACGACCACCAGTTCCGTGACGTCGGCGGATCCGATCACCGGAACCGCCTCGACGGTACGGCCGCCGACAGCATGATGCTTCGCCAAAAAGTGGCCGATCGCGCCGTCGCCCACCTCCAGTTCGGCAGCCGACTCCAGATCGGTCACCGGAGCGAGCAGCACGACCCGGCGCTTTCCGGCTCGTCCGGCCAACGCGCTCAGGGCGAGGTGCCCGCCGGCGGAGTGGCCGGTCACGACGGCGTCCCGCCACCGCTCGTCGCTCCCCTCGAGCGCGGCCATGGCCGCGACGCAATCCTGCACGGAGGCCGGGAACGCGCCGCCGTCCCACACCGGGCGGTACTCCAGGACCGCCACGCCGCATCCGCGGGCGACCAGAGCACACGCGAGTGGCTCCAGGTCGAGCGCGGTGCGGTCGTGCCGCCAGAAACCACCGTGGATCAGTACCGCCCGGCAGCGCGGTGCGCTGTCACCCGGTTCGTAGATGTCGATGCGCTGCCACGACGAGTCGCCGTAGCGGAGAACCTTCTGAGTGATGCTCACAGCACGCCGAACGCCTTCAGCCGAGTGACCCAGTGCTCGAAACGCTCGTCCGACATCTGAACCTCGGCCCGCCGCTCCGCCGTTTCGTCGGCGGCCCCCTCACGCCACCAGACGTGACCGTCCGAGCGCCGGATCATGAAAGCGCGGCGCTTCTGAGCCGGACTTTGGATCATCAGCGAGATGGTCTCGGGCTCGGTGATCGTGGTGTGCAGCTGATCATGGTGCAGCGTGATGCAGCGGCCCGCCGGCTCCTCACGGATGAAGTGCGGCCAGAACCGGTCGACGTCCGCGGTGTCGTCCAACGGTTGGTCGGTCGCGTACAGCGTGTGCTGGTAGGCCCCGCGCAGGATGTATGCGGTGAAGCTGTACCGGTGATTGTGCACCCGTTCGTACTGATTGGTATTCGCCAGCCGCAACCGGATCCGCAGACCCTTCTCCGGATCGTCCCAGATCACAATCTTGTCGTCGAGGGCGTGGCATTCACACTTCTTACGCAGCTCCGGCGTCCGGCGGACCCGGTCGACGAGGGCGCCCAGCATCTCCCGGTCGTCGCCGAGACGACGCGCGATCCGCTCGGTCACCTCAGCCGCGGCCTCGATGTCATCCCACCGCACGGTCGGCAGCGACGCCATGAATTCCACGGCGGCCCGCTCCTGCGCACTGATCACCGCACCACTCGTCATCGTTTCGGTCATCAGAGCACCTCCATGGCTCGCAGCCGGCCGGTCAGGTCATCGAAGTACTGCTTGCTGATCCGTTTACTTCCCCGGCGCGACGCCTTCTCCTGGTCTTCGCCGAACCGCCACCACACCCGGCCGGTCTCCCGTTCGGTGATCAGCGAGCGTTCCTTCTCCGCCGGACCCCGGAGGAACAGCGACACCGTCTTCGGGGTGGTGTAGGTGGTGTGGATCTCGCTGTGGTGCAGGGTGTAGCAGTTGCCGGCCCGCTCAGTCGTCACGAAGCGCGGGACCACACGCAGGTCGGACTCGCGCGCGTCGAAGTCGTCCTGAACGTCGTTCGGCACGTCTCCCAGGTTGCCCACCAACTCGTGACGCACGTGCCGGTAGTTGCCTCGCAGAATCAGCGAGGTGAAGGAGAATCGGTGGTCGTGCGGCCGGTCCCGGTGGTCCTCGGTCGAGACGTGGACCCGGATGCGGAACCCGCGGTCCAGCGCATCGTAGATCACCAACTTGTCGAGCAGCCGATGGTGCTCGCACTTGTCGAAGAGGTCTTCCTCCTCCCGAGCCCGGGCCAGCAGCTCCTCAAGCGCGTTCTTGTCCTCGGCCAGGGCGGTGAGGATCTCCTTGGTCTGCTGCCGCGCCTTGGGCAGGTCGGACCAGTCCACTGTCAGGCGATTCAGCGCGTCCAACATCCGTCGTTCCTCCGCGTTTCGTCAATGGCAGGCACAGCGGCGCGACAGCCCCGCATGCCGAATTCCTTGTCGTGGTCAGAGCTCACTGCGAATCGACGCTGAGGGCGGCCAGGTCGGTCCGCACGCCGGTGCCGAACGCCCGGTGCGCGGTCGACGTGGCGAGCTGCCAAAGATCGGCGTCGCTGATGCCGTTGACCTGCGCGTTACGCATCTGCTTGGCGAGCGGCTGGGAACCCGCGGCGACAATACCGCCGTCCTGGTACCACAGTCCGTTCTCCTCGGTCTGATGCAGAGCCTGGCCGCCGATGCGAGCCGAGTCGCAGCGATCGGTCATCATCATCGCGTTGGAGTAACCCATCAGTTCGACCGCGCGGGTGGCGATCGCCAGATCGACGTGCTCGCCATCGAAATTGATACAGGCCGACAGCCGACCCGCGGCCGCTTCCCGCATGATCACCGCGGGAACCGGGCCGGCGATCTCGCCCATGTCCGCCAAAGTCCAGTTCGGCAGGTCGTACGCGGCGAGCGTACTGTCTCTGACTTTGCGGGCCGCCGAGGTCCGGAAAGCGTGCCGGATGCGCAACGGCATGTCGTTGAAGAGGTGATCGGTGACCACCCGGGCCCCCTGCCCGGTCCACTCGCTCTGCCAGGCCATTTCCACGATGTCATGTACCAATTCGGCGCTGGCCAGCTCGTCGGCCCGGGTGAAGTGTCCCAGTGCGGGACGAACTCCGTGCTCCATGAGCAGGGGGACGATCCAGTCCAGGCGCGGGTGCCGATCGTCGAGAGCCTCGTAGAGACCGGAGGCCGCGGTGAAGGCATCGGGCGACACGACGGTGTAGACGAGGCCTAGCGAGCCCAGCTTCGCCAGCCGCTCCCACTCGTGCCGGGTCGGCGCCCACACCGTGGCCTTCGGCGTGCCACCGTGGCTGGCCAGCAGCGGGCCTTCCAGAGCGACCCCCGCGACATGGGGCAACCGACCGGCCCGGCGCAACGCGTGATAGCGGTGCATGAACTGCTCGAAGTCGGTCAACCGGTCCCGGTGCAGGTAAAGCGTCGGGATGCTCAGCACGCCCTCCTCGGCGCACTGGCGGTCTAGCTCTTCGAGGTCAAGTGTGGCGAACTCGGAGAAATCCACCCGGCCGAAACCGTGGCAGTGCACTTCGATCGGAAGTGCTAGCTGGTCGGTGTACGTGTTCAATGTCAGCCTTTCACTGCTGCCGCCGCAGGGCCTGTCACCCGGGCTGCGACGGGTTCAAGATGCCATCCCGTAACGGTGCAATTCGTCCGCGGCAAGCGGGTCGTCGAATGCCCCGAGAGACTCGAAGTAACGGACGGTTTGTCGTGAGGTCGCCGCTACGTGCTCTCGGACGACATCCGGCGTGTAGGTTTCATCGACGACACACTCGGCCTCCTCCGCGGTGAGCCCGTAGCCGACCATCTCTGCCCGCAGCGCCGGCACATCCGGTCTGAGGAAGATGTCGATCAGCCGGGGCACCAGCACGGCTGCCCGACGACGATCGTCGGATGACAGCTGGCCCCAGAGGAATCTCAGGAAAGCCGCGAAATAGGCGTGATGCCGGCCCTCATCGGCGGCGTGGTCCCGAACTGTGCCGCGGACCGCCGCGGAGACCCCGTCCCATTCCGGAACGTCCGCCAACGTTGCCGAGATGAGAGTCTCGGAAACGATGACGAACAAGAGCTCGGCAAGCGCTCGATCACGCTCGGGGAGTTCCGCTATCAGCTGTTTGAGCCGGACGATGAAGTACGGCTCATCCGGTAGCCGGGCGACCACGCCGGAACGCTGCTGAACCTGGCGCGCGAGGTCGACGGAGAAGAGCGTGTGGTAGGCCTCGTCGCAGTACATCTTGTAGGCGTCGAACCGCATCTCTTCGGGCAGGGTGACACCCACCGAGCCGGACGCGATGCCGAGGACCGTGCGGTTCACCACCGAATATTCCAAGCGTGCGGTGAAGTTCAGATATCGATACAGGTGCTGGATGAGCACCTCATCGAAGGTTTCCGGGGCCAGCCCCTTGATCAGGGGATGGCGGGTCACCGGTACGAGTTCGGCCGGGAAGTACGGCCGGATGGCCCCCTCGGTGAGGAGACGACGCGGTGCCTGACGGACGCTCGCGCGCTCGTGCCAGTTGCGAAACGGACTGCGATATTCGGGCTCGTTGCCGACCGCCTGCTGTGCGGTCTGTAGCAGCAGTTCTTTGGGGCAGTACGACAGCGCGGCACAGCCGATGAACAGGCCAACGGTTCCACACATACGAGCCTCCTGAACGCTAACCCCGATGGACGCATGACGATCTGGCGCGATGACCACCCCTCACACGGAATGCACCATGTCGTTCTGGGCCAACTGGCTGAGTAGTTCGAGGCTGTCGGCGACGGCTTCGGCCACGTCGACGTCGTACTCGGCGGCTACCTTCGCACCGATCGCTTCCACCGACGACTCGCCGTCGACCTGCCGGAAGATGAACTCGGCGATCTCGTCCAGCTCGAAGGCCAGCGAGGCGTTGGCGACGAACAGCTTGCCGCGGAATTTCCGAAACCGGGCGCCGGAGGCACGCTGGACAACGGACTGGGCGGTGAGGGTGCCGGCGGTAGCCATCAGATCTCGATCTCCACGGAAAGGTCTTTGCACAGGTGGGCGACCCGCGCGGCCCATGCCGCCGGGTCCTGCTCGTCGAAGTCGGCCATGGTCTCGACCGCCCAGTACCGCTCGAACGGGAGAACGGGCAGGCCGGCGTCGCGCATCCGGCGGGCGCGCCACTTCGGTGACCGCGATGCGAAGTCGTTGTTGCTCTCCAGTAGGGCATCAACGATGTGCCCGAACGCCTTGCGGGCCGCCAGCACGGCGCTGTGCGCGTCACCCGCGGCCAGCATCCCGAAAACGTCCTCCACATTGCCGTCGGCCTCGGCAAGCGAGCGGGTGGTCATGAACGCCTTGTATGCCGACTCCGCGAGCTGCGCGCGGCGGCGTTCGAGCCAGTCCGCGCCGAGCAGCGGCACCGCGGTGGGGAAGCGGCCCAACAGCAGTTCCTCGGGATCGGTCAGCACCTTCAGCGAGGAGATCCCGGCGTCGAACTGTTGCCAACTCGCCTTGGCCAACATCTGGTCGATCTGTCCGTCGAGCCAGTAGGCGATCTCCCACCGACGCTCCCCCACCTGGAGTTCCAGCGCCTGAACCGCATTGGGTTCCAGCGGCACCGGAACACTTCGGGCGCCCTGCACCGACCACGGCCGCGCGGTGATCGCGATGAAGTCGAAGTCGCTGCCCGGATTTGCCCAGCCGCGGGCGATCGAGCCCACCGCGAAAACAGCGAGGCAGTCGTCGGGCACCAGGGCACGAACCTTCATCTCGGCCAAGATGTGCTCGCGATCGATGATCATGTCCAGCCCCTGTCGTCGTTCTCCCGCTGAAGCTCCAGGATCACGTTGGGAATGTTGTTGAGAATGTGCGCGAGGAGCGCCGGATAGATCGACCCGGACGCCACTGTCAAACCGAGGAGCAGCACTCCCGCGGCAATCTCCACCATGGTTGAGCGGATCGTGCCGCGCCGGTTCGTGCCGGGCTGAATGTGGTGCCTCGCGACGAACGCGATCGCACCCAGCAGGCCGACGGGCGCGGCTGGGCTGACCAGCAACGCCGGCACCCGGAACACCGCCTCCTCACCCACCGCGCAGACCGTGGTGGCGAACGCGCGCGCCGCGCCGTGTGCCCGCGGCGTCGGGCCGAAGACGAAGGCCAACTCTCCGGACAGCAGTGACGGCAGACGCAGGTCACTGAGGGCGATGAGTCCGGCCGCCACCGCAACGGCGGCCCCGAACCACCACCAGTCGGCTCCTGCGGTCAGCCAGGCCGGCCGGGTGACGACCGTCATGGTGACCGCCACGATCGGGGCGAGGAGACCGCACAGCGTCTCCGCCCAGAAGCTCACACCACTGCGCATGGTGCGCGGTACCCGCCACGGCAGACACATCAGCAGAGCCTCGACGATCACGACGATGGCCATCACTCTGGCCCAGTCGCCGCCGACGCTCCACAAGCCGACACTGAACGCCGCCACACAGGACATGGCGATGAGCCGCCGTGAGTCCAGCGTCCAACCCGGTCGATCGAATGAGGTGGCGTACGGCCGACGGACTCGACCAGCGCGCACGTTGGTGACGGTCATCCCACGACCTCGGCGGACAGCGTGAGCACACCGGACTCCAGACCTTCGACCACCAGGTCACGTGCGACGGCGAGGGTGATGCCGAGAGTCTCTCGGACCACACCCAGCGGTGTCTCCTCGCCCAGTGCACGGAGCAGAGCCGGCCAGTGCGGGTTGTCATCCTCGTCGATCACATACTCGATGGCGCCGTCGACGACTACGTACCAGGTCGCCGGGTCGTCGGGGGAATGCAGCAGCAGCGCCCCGTCCGCGAGACCGACAACCGTCTCGTCGTCGATGGCCGGGCGCTGAAGCACCGCCTCCTCGATCGAGCTCCGCTGCTCGTCCCAATCGTGGACGGTGATGCTCTCGGGCACCGCTGCGGTGACCGCCTCGGCGGGCCGGGCCGGAAGGCTGTGCGTCATCTGCTCCAGCAGACCAAGGTTCACCGCGTGCAGCAGAAACTCGACGTGGCCTGAGGCGGGATCCTGCTGCAGCCCGTGCAGAGCCGTCCGAATGTTGTCCGCGTCGAGGAATTGCCTGGCTCCGGCGCCGCTCAAGGCCTCGTCGAGCAGGACGCCACCGTTCTGCGCGAGCATCCGGACGAACGTCCGGTAGGTGTGCAGCACACCGTCGCCGTAGAAGAACGGAACCTTGGGCCGGTTGACGACGTCTTGCGGAAGCAGGCCCGCCATGGCGCGCCGCAAGATTTGTTTGTCCCAGACGAGCGCCGGGCGCAGTTGCTTCGGAACCGCGGCGACCAGTTCGACAAGCCGGTGATCGAGGAACGGGACCCGGGCCTCGATGCCGTTGCCCGCGGCCGTACGGTCCTCGTGCCAGCAGTTGTACTGCTGCACGTCCCGGTACTTCCATCGGAACAACATGTCGTAGGCGTCCCGGCCGGTTCCGCCGGCGGCGTCACGCAGGACGGACTCCCGGACCAGCGACCGGTCCGACTGCTCCCACCAGGTGCCCAGGTCGGGCCGGGTCCACTGGGCCGTACGCAGCTCCATCCGGCGGACGTTGGACTCGAAGTCGGTCCAGTCTCCTCCACCCGCGAAGGACACCGAGTATCCGCCGTTGAACTCGTCCGCGCCGCCGCCCAGCAGCATCGCCTTGATTTCCGGCGCATACGCGCCGACGTACCGGTAGAGCTCATACTTGTAGAAGGCTTCGGGCCCGGCCAGCGGCGTCTCGAGCAGCCAGAGCAGCCGCTTCCATTCATCCGCGCTGGGCGTGACGGTGGTGTCGAAGAGCACCTGATGATTGACCAGGCCGACGTGGCGTGCGATGCGGTCACCGTATTCGGCGTCCCCGTTGAGCAGCGTGCTGCCGTTGAGGGCGGTGAATGTCCGAGGCTTCTCAGGCGCGAACGCGGCAACGGCGGCGGAGTCGATGCCGCCGCTGAGGAACAGGCCGACCTCGACGTCCGCCACACCGCACTCGGCCACCGAGGACGCGAGGGCATCCCGGTAGCGGTCGATCAGTTCGGCCTCTGAGCCGGTCCGGGCGCCGTCGAAGGTCGGGAACGACCAGTACTGATGGGTCTTCGTGTCGCCGGTGAGCAAGTCGATGGTGACGATGGAGGCAGCCGGAGCAAGTTCGATCTCCTTGAACCAGGACCTCGGCTGGCTGTCGTCCAGCACCATGGCACCGGTCATCATCTGGTCGGAGAGCGCGCCCAGCCAGTCAATCTCGCGGGGACAGGACGGATCCTCGAACAGCGCCTTGATCTCGGAGGCGAAGATGATCCGTTCCTGGTTGCGGTGGTAGTAGAGCGGCTTGATGCCGAAGCGGTCCCGCGCGAAAATCAGCCGATTCCGGTTGCGGTCCCAGAGCACCACCGCGAACATGCCGCGTACGGCGTCAAGGAAGTTCAGCCCGTCGCGGCGGTAGAGATGCAGCAGCACCTCACAGTCCGAGCCGGTACGCATCTTGGTCCCGGTCGGCAGGCCGGCGATCAGCTCACGATGGTTGTAGACCTCACCGTTGGCGATCAGCACCAGTGATCCGTCGTCGGTGCTCAGCGGCTGTCCGCCACCGACCGGGTCGACCAGGGAGAGCCGGGTGAACCCCAGATTGACGGACTCCGAGCGGTGGAACGCACGCCCGTCCGGACCTCGATGGGAGACCGCTGCGGTCATCCGCTGGAGCAGGGCCTCGGCATCGCCGCCGAGCGATGCTCCACCCAGAGCGGCGCATCCGGCCAATCCACACATGTTTCCCTCACTGGCGTACGACATTGATGAGACGAGAGACTCGTGGTCACGTGACGTCGGGCCCGCGCCCGGGTGCGGGCGACGGCCAGAAGAACTGGAGAGGATATGCCGCGCATACGACTACGCGGCATATCCTCGTCAATCAGCAGACGTTCGAGAGAACGGTGCCGAACACAACCTTCTTAGCCACGGGCTTGGTGTACTTGCGCATGTAGATCGCCTCCTTCCTTGGGTCGGGATACGCGACACGAAGATGGAAGCAAAACTCAGCGCCGAACACTCTACAATGCCGAACTGCTCAGTCTTTCCACGCGACTATGCACGGCATCCCAGGTGCACGAAAATCGCCCGTCGTATGGCGAAGACGACACCCGGAATGGCACAGAAACGTGTTATCCCCGTTGTTGCAACCCCGTAATAGATCCAGATTAGATCACCAGGTCGGCAGCCTGTCAAGATCATCTATTGCAACATGCTGTCGCCTCAGATCCTACACAGTGGACCGGCGAAACCGGAGAAGTCGTCGCGCCTTGACGTCATATGAGCAGCTCACAGCGGTTCCTGACAGGACGTTCAGGCGCGGTGGGCGTCTCCGACACAGCTTCGCCGGCGGTCGATCCCGATAGATCGTGGCAACCTTCACAACAGACACTCGCGGCACGGACGCACGCCATCGACGGCTAATTGCTTGCGCGCACAATTTCTTCTGGGACCGACCAACCTGCCGTCGCAAATGAAAACAGACTTAAGAGGTTCCGGCGCCCGCCGCCTTGCAGCGGATTTCCCGAGCAAGAAAAATGCTCCCGCCCGCACTCGTTTCCGCGGCAAGCCCTGTGAGAATCACGTTCACGGTTGGCAATCAGGCAATTCCGGCCATGACGCGGCGCGGGCACCAGACCGGAGCCGACCGCCTTCGCCGCTTCCTGCAACGTCGTGGCGGCCTTCGCCACGTCCCGCCCGATACCGCGCAACGCCTCGGCATCAGCCTTCCGCAACGGCATTCCCCTCCCCCGAGGGAACATTGCGGCCGACAGACCGTCCACGTCCCACTCCACCGCGGGTGACACAGCGAACCGCGAGAGGCCGGAGGGGAGAACCCGTGGGCTGAAGCCGACCCGTCCGAACCTCATCCGGGCGAAGGAACATCCCGTCAGGCATCGCCTCGCGCCGCGAGCTCGGGCCATCCCTCCAACGCGCCGCTTCGGGTCTGCTGTAGTGCCCGAATGCCGGGTACCAACATGATCGCGGTGGCGGCGGCGATGACGATGACGAGCGCGATCTCGAGAGTCGCCGCGTTGCCGATCTTCTCCGAGAGCGGTCCGACTGCGCCGTACCCCAGCGGCGCCACCGCGAAGGAGACGAGCCAGTCGTAGGAGTTCACCCGCGACAGCACCTTCTCGGGAATCAACCGCTGAACGGAGGTCGTCCACAGATTGTTGGCGTAGGCGATGCCCGCGGCGCTCACGAACCCCGCTGCCATGATCACACCGGTCGGAGAGGGGCCGATGAGTGCGGACAACTGCAGCACTACCAGCAGGAGAGCGACATGTGCCGCCACGAGGGGCCGCCGGGGCTGGACTCGCAGCGCCACCGCCGAGCCGACCACGGCGCCACCAGCCATGCTGGCGCTGACGAGACCCCAGCTTGCGGCACCGCCGGTCTGGGTTGCCACGATGGCCGGCCCCAGCACGTAGAACGCGCAGGAGCCGACGTTCCACACCCCGTGGCAGCACACCGCACCCCAGTACCAGGTGCGCGCGGCCATCTCTCGCCAGCCGCCGACGATGTTCTTGAGGAAGCTCTCCGGCTCCCTGTCCGCCATGGGCGCGAGTTGGAGACCGATGACGGTCACCGCGCTGACCAGGAACGTGGCGGCGTCGAGCAGGTAAACCCACCCCGGCGAGGCCAGGGCGACCGTGGCACCCGCGACGGCGGGGCCGAGGATCTCCGCACCGCTCTTGGACAGCTCCATGAGCGCGTTTGCCTGCTGCAGCCGCGCATTGCTGACGGTCTGCGGCACGATACCGATGAGTGCCGGCTTCGAGATCGCCGACGCCGCGCCATAACAGAGCGCCGCCACCAGGAGCATCCCGACGCTTTTGTGGCCTTGCAGGAGAAGGATTCCGACTACCGTCTGCACGCAGAACAGGAACACGTCGCTGCCCATGAGCAGCAGCCGCCGCGGTAGCCGGTCGGCAAGAACCCCGCCGAAGATCAGAAGCACCATGCGGGCCACCATCGTGGTGGCCAGAACCAATCCGATATCACTGGCGGATCCGCCGACGGACAGCACGGTGAACGTCACCGTGACCGGCATTAGCGAATCACCGACCGCCGATGCGGTGCGTCCGCTCCACAACAGTCGGAATGGACGCTCCACCAGCGCGCCGAATCGACCGTTACTCGACATGATCTGTCACCGCACCATCGCCAGTTGGAAGCACAGGCAGCGGCTGCCTCCGCTAGTTCGGACTCGTGAGACGTGGCCCCGGCACGGCCCCGGCGGCCTGCGCCACTCGCGCATGCGCGAGAGCGTCGGCGAAGCTCCATAATGGTCGCCGGAGCGGGGGGACCAAGGGCTTTCCGACCGCTCGCCGTCCGCGGGAGCGGGTGGAGTGCGTTGCGATCCGGCAGAATGGTGGGAACCATTCGCCGCAGCCCGACTGCGCCGGGTGGGAGCCGCGTTCAGGCTACCACGTGGCACTCTTCACTTCGGACCGTCGGCCTGTCGGCGATCGTCGATCCGAGGCGCCACCGATCTCCGCGCAAGATAACATCACGGCCGCTGCAGTTCGGCCAGCACCAAACGCAACCGGGAGTACACCATGCTTCTCTTCGTTGAGTCGGCCCCCACCGGAGCCGGAATGTCACATGTTCGGTGGGCCGTCGATCACGGCTTCGACGCCGCATATGTGAGCGCCAACCCCGAGTGGGCGCCGGAGCGCCTGGGGGGCGAGGTGATGGAAACGCTCGAAAGTCGTGGTCGTGTCTTCAAGGTGCCGTCCTCCGAGGTCACCGAGGTGCCCGCGTGGCTCGTCAGCAGCATCGAGCAGGCCGCCGGCCCGTCCGGCGTGGTGTGCGGACTGGACCGCAGTCTGCCTTTCGCGGCCGCGCTGGCGGAGGCGGTGGGCGCCCCATACCCGTCTGTGCCGGCCATGCAGACTTTCCGTGACAAGCGGGCGGCACGCCGCCTGTACGACAAACTCGGGATTACCTCTGCCCGATGGGCGGCGCCGGCAGACGCCGACGAATTCGTGGCGTTCACCGAGGAGATTGGCGGCCCGGTCGTACTCAAGAACTGCCGCGGCACCGGCAGTATGGATGTGCGACTGGTGGAGTCGTCCACCGAGGCGCGCGAGCGGTACCTCGAGCTCAGCAACGCTGAGCGGTACCTCGACGGCGATCTGATGGCCGAGGAATACCTCACCGGGCCGCTATACAGTCTCGAAACGATTGTCTCCGACGGAACGTGTCACCACCTGGGAGTGACCGACCGTCAGATCGGCCCCAACCCGGGTTTCTGCGAGGTTTCTTACACTTTCCCCGTCCAGGTGCCGTGGCAGTACGAGAATGAGATGCGGCGGGCCGTCGAGGCGTGCGTCCAGGCGTACGGCATCAGGCAGGGAATGCTGCACACGGAATTCATCGTGACAAGCCACGGCGCGGCCATCGTGGAGCTGAATGTGCGCCATCCGGGTGGACTGCTGACGATGATGATGAGCGACTGCCTGAACAGTTCCGTCTCGGAAATCCTGAGCTTGTCCGCGTTGCAGATGCCGCTGCCGGATCTCAGCCACAACGGAAAGGCGTCGACAACGGTCACCGTGTATCCGCAGGTGGCCGGTCGACTCGTTCAGATGCGCGGCTTGGACGAGGTGGGTGCGGCACCGTTCGTCGTGCAGGCGCTGCCCTCCGCCGCCCCAGGGGATTGGGTCCAACCGCCGACCGACTACCGCGGCGCTCTCTGCCAGATTCGCACCGTCGCCGAATCCAGCAATCTGTCGTTCAATGCTGCCATGGCTGCGGCGCGGGGCATCTCCGCCGTCGTCGAGTAGGCGGCCGAGGGTCAGCTTCCGCCGTCCGCCTCGGCTGCGACGACCTGCTGGATGCAGGACAGGAGCCGCTCCAGCGGTTCGTACCCCGGGGTGGGTGGCGCATCGCGCAGGTCGCAGGTCAGCTCAGTGTCGTCATCGACGACGAGGTAGACGGGATAGCCGTTGTCCCGGCCCGCGTCCCGCGTCGTTATCCGTGTCGGCGGGTGTGCTGGTGCGGCGACGGTACTCCGCGCGGGGCGCGGCATGTAGTTGTAGAAATACGTGAAACCGAAACCGGACCCCTCGTACCCCAGCGATCCCACCTCGCGCGACACGACATCCACATTGTGCCTTCCGTGGCGATACGCCGTGATCGTGTCCCAGTGCACCCGCCGCACCAGGGCCGAGAAGCTCTCCGCCGGATCGACTTGCACGCGCACCGGCGATACCTGCTCCACCGTGCCCACCACCTGCTTCATGCGGGTGCCGGCCCGGTTGCCGGAGATCAGCGCCACCAACGGTGAATCGGTGTCGTCCCGCTCGGCGATCGCATGGCAGTAGGCGGCCAGGACAACGCTGTGCAACGACGCCCCACACTCTGCCGCGAGTAGCCTCGCCGCCTCGCGCATCGTGGACGAGCGCAGCGTCGCCCACCGGGTACGGAGGGTGCCCAGCGAGGCCGCTCGGCCGCTGGGCACGTCACCAACGGTTCGTGTCCAGTACTCCACCGCCCGCGCGGTCCGCTCGACTGCCGGGTCCGACTGCTCCTCCCATGCCAGTTCACGACAGCTCACCGCGGGGTCCGTCAGAGTGCGGCCGGCCAGAATGTCGGCGAACTCGCGGTGCAGCCGCTGGATCGCCCAACCGTCCACGGCGATGTGGTGCCAGCACAGCGCCGCCCGCACGGGCACGCCGCCGATGGTGAACACCATGCCGCGCAGGGGTTTCTCCGAGTCCAGCGAGAAGGTGCGTCGACGAAGCTCCTGCGCGTGCCGGTCGGCGTCTGCGGCGTCGGTCACCTCCAGCACCTCGACCGATACGCCCCGCGGCGCGAGGATCACCTGACGTACCGCGAGTGAAGGGGTGTCCGGGAAGATCGTCCGAAGCGACTCGTGTCGGGCCTCGAGCAGGTCCAGTGCGTTCAGCACGCTGGTGACCGTCTGGCCCGGCGGGACGTCCCACGACCGCACCAGGTTGAGGCCATCGGGGGAGCCGGCAGGCATCCGCTCGAGGGTGCGCAGACACGACAGCTGGCCCAGTGTCAGCGGGGCGACCGCAACCTCACGCACTGCTTCTCCCGGTGTATTCGCCGTCCGGTCCGCACCGAACACCCGACTCAGATGAGCATTGTGGTTGGTGGCCGTGGGGCTGCCCCACGGCGCTCCGGTGGGTTCACGTGGCGGGCGGCACGGCGCCCGCCACGTGGAAGGGGCACCGCTAACGCCCGCGCGCCGCCGCCCCGAACGGCGGCTCCCCGGCCGGCGTGAAGATGACGGGCTCACCGCCGGCGAGCCTCGCGCGCATGTCGCCGTGCCATTGCACGAAGCTGCCGTCCTCCGCGACGCCGCTGGTCAGCCAGCGCGGTTCGGCATACCGCTCCGTACCCAACGTCGCCGCCATATCGGTATCGAACATCGCGTCGACGTGGTGGCAGACCCAGCCCACCGCCGGGCCGACGCCGTTGTCCTCCACCACCTTGATGATCTCGGAGGCGTGGTTCGCCCCGATCCGACGCCAGAGGCGCACGACATCCGCGAACTGGTTCAGCCGCACGGGCTTCTTCGTGATGAACCACGCCTCGCGGAAGAGATGCAGCACGATGAACAGCAGTGAATATGCCGGCGTCAGTGTCGGAAGGGTGCGGTCGGACCGTCCCGGCCGTACCAACACCGAGTCCAGATCGCGTAGTACCGCGTCCATCGGGATCTGCCACGCGCTGGAGAACCAGGTGAGGCTGAACGCGACGTCGATCTCGATCAGCGGCTGCGCCCGATTGCCCGTCAGCTTCGTGAAGTGCGGCAGGTGGTCGGGGTACATCCGATACACCATGCGGCGGGACCGGGGCAGGTCCACGAGGCTGTTCGTACGCGCGTCGTACTCCTTCGCGACGGAGTACCCGAGGCTCGTAAGGGTTTCCGTGATGATCGCGGTGCTGTCCGGCGGGATCATCAGATCGATGTCGGCCATGACCCGCGTGCCGGAGTTGTCATACAGGGTGGACTGGTTCACGACGCCCTTGGTGAACGCGAGGCGAGCGCCGGCGGCGGCCATCGCGTCCGCGACGCGAGACGCCTCGTCGATCAGCTCCTCCGTCCGGTAGTCGCAGATCTGCGCGAGGCTCCCGAACGACGCGAGTACCGGATCGCTCAACCGGTTCTCGATCCCGTTGTCGACGAGAAACCGCCACATGGCGGGAGCAAGGTGGTGCCGGAGCGCCTGCACGGTCAGGTAATCGAAGTCCAGCTCGGTCTCCGCGAGCGCACGGGCGGCGTCGTGTGCGCCGGGGCGCCCGTCGAGTACCGACAGAGCCTGCAGGAATGACCACTCCTGCGCGCGTTGATGAACGGGGGCAAGCACCACTTCTACTCCACTTCATGTCAGCGAGGCGCGACTGGCCCGCAAAGGGTCGGCCGAGGCGATACCCCCAGCGCATTTCTCAGTGCCGTTCGTTGGAGGAACCTCCGCGAAAGCGCGTGGGTCCACGCCCCTCAGTCGCTTGCGAGACCGAGTGAGCCAAAATGTGACGCGGCACTTTCCGCCGATTCGGTTGTTACCTGGGCGCCGTATTGCCGGTCGCGCACGCGGTCGGGCGCCTGTCGACCACGTGTCTACGAACCGGGAACGACAACGCTGCCGTGTGCTGGTCCACGGCGACGTCCGCGCTGTAGCTGTAGATCTCCGCCTGCAGCTCCGATGCCGTGGACGATACCGCGTTGGTGCGGTAACTGAACATGATCGTCGGGTCCATGAGCGCGGCGAACCCGAGCACCAGGTCGGCGCAGTCACTGGCGGGCTTGCCGGTTACCTGATGCGACGGCTTGGGCTCGAAGCCCAGCCGAGACTTGAAGCGCAGCAGGCCGGGCTCGACCACGTGCCCGTAGAGGTTCGGGTCGGTACCGAGACTGACCGACCGGTAGCCGCGCACGCGCGCTTCCCGAATGGCTTCCAGGTACAGCGCCCGAGCCAGACTGGCATACCGGCCGGACTGGTCGACCGCGGAGAACCGGATCCGCATGGCTCCCTCGGAAGGTGCCAGGTTGATGCATCCGCCCACGAACTCATCGCCCCTCCACGCAGAGACCACGAAGTAGTCGGCCGCGTCGGCCAACAGGTCGCCTCTGATGTCGCTGACGACGGACCAGCCATGGCGCTTCTCGGCAGTCCTCGCCTCGTAGAGAGGCAGAAAGGCATCCAGATAGGTGGAGTCGAGGTCGCCGAGCCTGAGCCGCACTCCGTCGGCGGCGGCGCGCCGGCGGGCCGCGGCTATGCTTTGCCGTTCCTTGCGCGGCATGCGTCCGAGGAACTCGTCCTCGCTCGACTGGCAGTCGGCAACCCAGGTCAGCCACTCAGGCTTGGGCAGGAGACCCGCACCGGCGAGTGCCTCCCACGCCTCGACCGGTGGATCCTCGACCCGTACAAGGTCCTCGTGGCCCTCGTACCCGTGCCAGTCGGTCTCGATGGCGGTATCGACGTCGACGAGGAGCATCGACAGCCCATGCCGTACCTCGGACTGCGCCCTCATGTCTGCTCTCCGCTGAGGCGCACCGAGCGGTCCAGCATACTCAGTACCCCGGTGGCCACCAGGAGTCGGTCGTTGGCGTAGTTGAGGCTCGCCGAGCGGAGGTCTCGGAAGTAGCGCTCGAAAGGCACTGCTGCATCGCGCCGGTACCCTTGGGCCAGGCCCGCGATCTCGACGATGCCGTCGATGGCGCGGAAGCAGGACTCCGACGCTATGACCTTGAGGGTATTGAGGTGGATCTGCGTGGCGGGCTCGTCGAGGTCTCGGCTGTTTGCTCGACGCTCCATCACCTCCTGGCACACCCGGGTGAGGTACGTGCTCACCACCTCGAGCTCCATCCGGACCCGGGCGACGCGCGCGGCCACGAGTTCCGACTTCGGATCGAGGCCACGCGGTCGGTGGGGGGCTCGGAGCGCGAGCAGCTCCCGGAGAGCCCCCTTTGCCGTGCCCAGCCAGCAGGCCGACCACCCGAGGTGCGCGAGGGGCACCAGGCTGTTGGCCGCTACGTGGCGGAACCCCCCAGGCTCCCCCACCACCTGGGTGCCGGGTACCTGTCCCCGGAGGTGAAGGCCGACGCTGTGCGTTCCACGCATGCCCAGTGGATTCCATGTGCCGCGTTGGTCGATGGCCATCTGTGAACGATCGGCATAGACGAGCGTCACCTCGGTTGGTGGCGCGTCCGGCGCGGCGAGCATCGTGGTGAGGAAGCCGTCCGCGTACGCGCCGCCGGTGACAATGGGCGCGTCCCTGTCCAGCAGGAAGTCATCACCTGCCGGCTCCAGCGGGGACGCGCTGGTGAACAGATGGCCGCCTTTGGTCCGCTCTGAAGTGATGGAACCCAGATAGACCTCACCACCCGCGATCCGCGGCAGCAGCTCGGCGCGCAGCTGCGGGCCCGCGAACTGGACGACGGCATCCACCTGTTGGCAGTGCATCGCCCAGATCATGGCCGTGGACAGGCACCGGGAGGCGAGTAGGCCGGCCACCTCGATGAGGTCGGGAATGCCACCGCCCAGTCCGCCGTGTTCCACGGGCACGAGGAGACCCATGAGACCGCTCGACCGGAGGCAGTCCAGACTCTCCACCGGAAACAACGCCTCGGCGTCGATCCGGGTCGCGTGCGCGGCGAGGGTCGGCAGGACCGCTTCGGCTCGCTGCCGTACGTCGGACCGCAGGGTGTGCTCCATGGTAGGCGTCGCCATGTCTACGCCAGCCCGTCGACGGGTGACCGGAGTTCGGCGAGGGCACTCCACAGCGTGCGCGGCGTCGCGAACGTCGCGAACGTCAGTGCGTGATCCGGGAAGCTGACGCCGAACTCCTCCTCGAGGTCGACCAGGAGGCCGATGATTCCCATCGAGTCCAGTCCGAGCGCACGGAGGTCGGCGTCCGGGTGGAGCGGCTCCGCTTCGGCGGCACCGCCGAGACTGCGTTGTAGGAGCCGCACGAAAGACGGGTCAAGGTCAGGCGTCATTGTTCTCTTCCTCTATAGATGTGCGGCGCAGCTCGAGACGTGAGGCAGTCGGCTCATGGCCGCGCCGCACCACCACCTCGGTGGCGACCGGCCGGCTCAGGAATCCCATGAGGCTCGCGGTGAGGCCGTACGCGCCGACGTTCGGGATGGCCAGGATGTCGCCCGGCTCCGGTACCGCGGTTCGAACTTCGCGGCCGATGAGGTCCGCCGACGTGCACAGCGGCCCGACCAGGTTGACGGCTCTCTCCGGTCGACCGCCCTGGCTGCCGTCGACCACCTCTGGGCGGGCCATGGGCAGCACCCGACCGATACCGGACAGCCCACCCAGATGGTTGATGCCGGCGTCCAGCACCGCATACGTCTTTCCCTTACTCACCTTGACGTCCGTGACCGTGCACAAGAGAGTGCCGGCATCGCCCACGAGGTACCGTCCGGATTCGAACGCGACCTCCGGCCTACCGTCCCGCCAACCGCGCATGCGCTCGTCCAGGACTTCGATGAGCTGGGCTCGCAGGTCCGGGAACGTAGGGCGTTCACCCGGCTGGGCATACGGGCAACCGAAGCCTCCACCGATGTCGAGGAACTCCAGCGCCAACTGGTGCTCGTCGCGTAGCTGCGCCGCCATGTCGATGCTGGCGGCGAACTCGCGGAAGAGGCTCTCCTGGTCGACGGCGTTGGTCAGCGGAAAGAAGTGCAGTCCGACGATGCGGGCGCCCGGGGTGGCGAGCAGGCGGTTCCAGTCCGGCGGCGACGTCGCCAGATCGAATCCGAACTGCGACGGCATGCCGGTCATCCGCAGGCCGCTTGCTCCGGCGGGGCTCAGGCCGTTGATCCGTACGATGCACTCCGCGGTCACGCCGTGCGCCAGCGCGACTGACGCCACGCGCTCAAGGTCCGCCTCGGATTCGACGGAGAAGCGGCGCACCCCGCTTCCCAGAGCGTTGGCGATCTCTGACGCCGTCTTCCCGGGGCCGGTGTAAAGACACTCGCGCGGATCGGCGCCCACACCCAGCGCGGTGGCCAGCTCGCCGGAGGAGCTCACCTCGGCCCGGCAGCCGGCGGCGATGAGCCGTTCGACGACAGCGGGATGTGGGTTCGCCTTCTGCGAGAAGAACAGCGTCGCCTGCTCAGGAACGCTCGCCCGCAGATCCACGAGTGCAGCGTCGACCCGGTCGAGGTCGTAGACGTAGAGCGGACTGCCGAACCGCTCGACAAACTCACGACGGTTCACGATGTCGCGCCCTTCAGCAGGTGGTCAGCCAGCGACTTCTTGTCGGTCTTGCCATTGGGGGTCAACGGCAGCGAGGCGACGACGTGGCAGTGCGACGGCACCTTCGCGGGCTCCAACCGGACCGACATCTCCCGGAGGACCTCCGGGCCCGTCAGTGCGGCGTCCACGAACATGACCAGGTCACCATCGGCGGTGGGCGGCAGGACCGCTGCCGCGCGCACGCCCGGGATGTCCACCGCAGCGGCCTCGATCTCGAGAACGCTGACTCGGGTACCCCGACGTTTGAAGAGGTCGTCGCGCCGACCCGCGAAGTAGAGATATCCCTCCGCGTCCAGGTACCCGTAGTCCCCGGTGTAAAGGGCGACCGTGCCGGTCTCGCGGTCGAGACGGAAGCGCTGCATGGTGAGCTCCGGCGCGTTCCAGTAGCCGGCCATGACATGGGGCCCCCGGACGACGATCTGCCCCGTCCGCCCAGGCGGCAGGGGCTGGTCGTCGTCGTCGACGATCGTGACGCTCGTACCGCCGAGCGGGCGACCTACGGAGGTCGGCCGGAGCAGCACTCCGTCGCCCTCCAGGATCGAGACGCGCTTGCACTCGGTGATACCGAACATCAACCTGATCGTGACGTTCGGGAACGCCTTTTGAAGCTGTCGAATGAGGTCCTCGTTCAGGGCGGCGCCGGTGTTGGTGATCATGCGAAGGCTCGTCTGGTCTGAGGTCCGTCCGGCAAGCCGGACCAGCATCTGACCGAGCGACGGGACGATGGGGACGACCGTCACCCCGTGTCGGCGGATCCACTGCAGGAGCTGGAGGTCCGGGCTGTCCGCCGGCGGCACGAACACCTCACACCCGGCTATGGAAGCCAGGAGGAGTTGGTAGAGGCCGTAATCGAAGGAGAACGGGAGGCGGCACAGGACGACATCGTCTGTCTGGTAGCCCAGCTCCGCTGCGATGGCATGTGCGGCGAAGGCGACCTGCGCGTGCGGGCACACCACTGCCTTCGGCAACGCGGTGCTACCGGACGTGTAGATGAGCAGCGCAAGGTCATTCGGTGCGGGTGTCGGTACCGCGGGCGCCGTCATCGGGAGCTTCCGCATCTGCTCGACGACCGCGCTGAGCGCGTGAACCGGTCGCTCGGTGACCTGGCTCATCAGCGGCACATCGGAATCCGTGGTGACCACGAGTCGCGGGTCCGCGTCCCCGATCACCGCGCGCAGATGGAACTGTCTCATTTCTGTGCTGATCGGCACCATGACAGCCCCGATGCGGGAGCAACCAAAAAGGATCGCCGCGAACTCGCGCGTATTTGTCAACCGTACCAATACGCGGTCGCCGCGCTGCACGCCGAGCTGGATCAGCCAGTTCGCGAAGCGAAAGCTCTGCCGCTGCAGCTCCGAGTAGCTCCAGCGCTCCGTGCCGTTGTTGATGGCGGAAGCTTCAGCGTTATTGGCGACCGCCGCATCGAGAGCGCTGTGCAATAAGGCGTCCTCGCCATTGTCCCCGCTGCGGCCCGGCGGGCAGCCGAGGTCAGCGTGTTCATCGATCTGTATGTTCCCCACAACCGTCCTGACTATCGGATATGCGTACCGGTGACCCCGTCACCGGAATCGTCGGTCGACCCGCCGGTCCGTGGGGACGGGCCGTCATCGCGATGATGAATGTGGGGCCGGACGAATGGCGCAGCGAGCTCGCACCGATATAGATCATATCAACCACGGGCCAGCCGGTGCCGCCCGCCCGACACAAAAGACTCAGCGGCGCATCGACCACGCTCCAATCCCGACGGATCGATTCCCGAGCGCCGGTGTCGAGCGGCCCGGGCGCGGGAGGTCCGTTCGCCGAGGTCCCAGCGGGCTTGATGGCCTTCGTCGCGACATGCGGTCAACGCGGCCGGCTGAAGTTCACCACCGCGGCGCGGCCGACACAGGCGCATCTCTCCGCGGAAGCCGGCAGATCCCGGCGAAACGTCGCTTGAATCGGCGCCGGGCCCGTCGGCGTTGAGCTCGGTCGCCTCGCGACCGCGACCCCTCTGGGCGCCGTCACTCGCGCCGGGATGCTTGAATGGCACCCGTTCCGGTGACCTACGACGACAGTCGTGTGTCGACCCGCCGGCCGCATCGCCGGCCGCCGTCCACTGAAGAGCACGCTCGCCGTGCCGGCCGGACGCCTCGAAGCCCATGCTCCCAGCCATCGACACCAAGGAGACGATGCGACGTTGTCCGGAAGCGAGCCTCACCACGACGGCAGCACGCGTGAGTTGCGCGACCTTATGCGCCAGGTGGCATTTTCTGTGAGCGTAGTCACTGTTGCCGGGCACTCACCGCGTGCCTTCACCGCAACGTCGTTCACTTCTGTGGAGATCGATCCACCGCTGATTTCCGTGTGTGTGAGTCAAGATGGATCAGCATGGCCGACCTTACGGGACGCCTCGCACATCGCCGTCAATGTTCTCTCTGAAGATCAGGAGGATGTGGCTCGACTCTTCGCCACACCCGGCATCGACAGGCTTGCCATCCATGGCGACTGGCGACCGGGTGAACAGGGATGCCCGTTGCTGGGGTCAGTCCTGGCGCACCTGGAGTGCAAGGTCGCCCATTATGTGGAGGCCGGCCGACACGCGATCGTGCTGGCCACGCCCACCAGTCTCGCCTGGCGGGAGGGGCGCCCGCTGATGCGGCACGGCGGCACCTACACGGCACTTGCCTACTAGTGCCTTGTCACGGTCTTCGACGGCGTCTGCATTTCGGTTGCGTGCGGTGGGCTTGGCAGGTCGGGCAGGTGCCGAGCAGGTGCGGCAGGCATCGGCGTACACCGTAGAGGGTCATTGCGGCGCAACGGTTCTTGTGTCCAGTCCCTGCAGGATGCAGGAGGCTCGGGCGGCCGAGACCGATCCAGGTCCGGCCTCCACAGTGGTCCAGGCCGAGGCGCACCTATCGCCCTTTGGCCCCACCGGGTGGAGGATGGTTGATCTCTGCTGTAGGTTGCTCCGAGCGCCTGGATCAGTCGGGCGTGGATTCGGTATTCCGTAACGGGGGGCTCTTGCTTGTGTGCGTCACCACGGGGCTATCATTCGGTGGACGTGAATGTCGCCGTCGTCAGGAACAGAGTCACGTCGCGAGCCCAGGGCGTCGTCGCGTGCTTCCCCGCACGGCCGGAGAATGCGGTCGGGGATCCCGAACATAAACTCATCGCAACGGTACAGGCCGTCTCTGGCCTCCCCCATGTCCGCCGAGCGAGCCAAAGCAGTGCAGCGTGTCACCGTCCGTGTACGGCCATGGCGAGCATTCTCTTTCGGGCCAAGCGCAGGGCGACGCTCTCGCTCTGTCGAGATTGCGTTAGAACCTTGGCGGTATGCCCAAGGGGCGACGCGCCGGGGGTTTTGCAGCGCCAGTCGCCTGTCTGACTGAGCGCTAACGCAGCGCGAATCGCGTGTCCTTCGGCATGCAATTCGCCGGCGTGCGGCCGATGCGTCGGACTCCGCTGCCGGATTGCGAAATTCTGCCGATCTACGAATCGTGCGATCAGGTGCTAATGCACCTTCATGTCTTGACGGCGCGGCATTTCTGTACCGCGCGTGCGTTGGTGAGGAGAGGTAATGATGAACAGGCTCGCCATCAGGGGCGGAGAGGCCGTCCGAACTGCGCCCTGGCCGGTGTGGCCACGTCCCGCAGAAGGCGCGAGTCAGGCGCTGGAAACCGTGCTCCACTCCGGCCGATGGGCCATCAGCGGCCCGTACCGTGGCACGGAGTCGTTTGAGCGGCAGTTCGCTCGCGCGTTTGCGGCCTATAACGACTCAGCGCACTGCATTCCAACAGCCAGCGGCACGGCGAGCCTGATGATCGCGCTGGAGGCCTGCGGTGTCGGCGCCGGCGATGAGGTCATTACGCCAGGCATCTCGTGGGTGGCGTCGCTGTCCACCATCACGGCGGTCAACGCGATCCCGGTCATCGTCGACGTGAACCCTGACACGCTGTGTATCGACCCGGACGCGGTCGAGGCCGCGATAACACCCCGGACGAAGGCGATTATCGCCGTACATCTATATAGCGCGGTTGCCGACCTGGACCGCTTGAGCGCGATCGCGGACAAGTACGACATCACCCTGATCGAGGATGCGGCGCAGGCTCACGGCGCTGCCCATCGCGACCGCAAGGTCGGCACGATCGGTGCCGTCGGGGCGTTCAGCATGCAGCACAGCAAGGTCCTGACCAGCGGCGAAGGCGGAGCGACGATTACCTCCGACGGAGGACTCGCCCGGCGGATGGAGCAACTGCGTGCCGACGGTCGGTGCTTGGCAAAAGTCCCTCCGAGGCCGGGATGGATGGAGCTGGAGCAGGTCGGCGAGCAGATGGGCAGCAATCGTTGCCTTTCGGAATTTCAGGCTGCCGTTCTGGTCGCACAGCTCACTGCGCTGGATGCACAGAACGCGACTCGAGCACGCAACGCGATGCTGCTCGACAAGCTTCTCGCCGACGACGGTTGCCGCCCTCAGCAGACTTCTTCAGGTACGACGGCGCGTACCTATTACGCGTACGCTGTTTCGCTTCCGGAGGGTGCGCTGCCGGGCGTGCCGCGTGAGCTGGTAGGCGAGGCGATCAGTGCTGAGCTGGGTTTCCCGGTGAAGCCGCCTTACCTGACGCTGTCGCGAAGCAAGCTCTACCGTCCAGAGACGAGGCGTCGTTTCGCACTAGGCGCAGACCACCTCCGCAGGTTGGACACATCCCGGTTCGAGCTGCCCGAATGTGACGCGGCGAACGGCCGTGTGCTTACCTTCCACCACGCCGCATTGCTCGGCGACGAGGCGGATATGCACGACATTGCCGCGGCGTTCGCCAAGGTCCTTCGCAACGGCGCCGTGCTCTCTTCGGTGGCGACGGGGTCCTGAGGTCGTGCTACTCGATGCCACGGTGCGTCCGGCCGGCGGCGCCGCGCCGTTGTGGACGCCGGACAGGCTCTGGTCCCAAGGCCCCAGTGTCTTTCTTCATGACCAGGCTACGGACGGCGTCCACGAGGCACACCTCGCGCACGGCGACGAGCCTGTGCTCCGGTTCGGTCACTGGCACTCGCAGGAAGCTTGGTGGGCGCTGCAGCTGGGACGGACGCGCGCCGCGCACCTTCAACGTCACCTGGCCGGCCTGCCGAACGGGGCTCGGACGCGGGTGAGTGCGGTCGCCGCGTGGACGGAGAACCTCAGCCTTGTCGCGCTGAACGACTATGACGAGGTCGACCCACCGAGCCTGGTCCTTTTCATCGGCGACCGGATCAGCCACGTGGTGACCCTCGACCGAGAGTACGCGGCACACGTGGGCGACGCCTGTTTCGCCTCACCAGAGCGCATAGTCGTCACCGACGACTATCTTCATCTGGTTCAGTGTCTCGACCTCTCCGGCAGGATCCTCTGGCGCCGAGGCGAACGCGGCAAGCCGGGTGCCGACATAGCAGCGCTGTTCACGCCGATCGCCTGCTGTGCTCTCGACGGCACGATCGTGATCGCCAATCGGCGGTCCTCAGACCTGATCACGCTCGATCTCGATGGAAACGTCATTCAGGCGAGCATTCCCGGCGCGCACGTGCGTTCGGCGAGTGCGATGACAGCCTTGGATGACAAACATGCCCTGATCTCCGATGCGTATGCGGGCAGCCTCCACCTGCTGACCGCGAACAGGGACAGGTGGACGCTCGAGAACGTCGCCCACCCGGAGCCGACGCCTGCCACCGGCGAATTCTCGTTCCCTCGTGCAATCCTGTCCGTCGACGAGCGGCTGCTGATCGCGGACACGAACAACAGCCGCCTTCTGTGCTTTCCCGGTGATCCGCCGCTGGCGCTGCCCGTGCCCGGCTGGCCCCGTTCCGCCATCGTGGTGGACGACGCCGTGCTGGTTGCCGACGGCCTCGGCAGCGTCCTTCGTAAACATCCGCGACACCTGTCAGCGGACACGCCGGGGATCCCTCTGGAGGTGCGCGATCGGCAGGGTCGTCCCGTCGCTCTGGCTGATCCACACCATCTTGCTCACCACGACGCGAACAGCTTCTGGTTGACGGACAGCTCCCTCAATGACGTGTTGTTGATCACGCTTGACGGCACCGTGTCATGGCGCTGGACCGAAAGCCCGTTGGCAGACCTGGCGCCACTGTCCGACCCGCACCAGACCCTCCCGCTGACGGGAACGGACGAAATACTCGTCGTCGACTCGCTGAACCATCGGGTGCTCCAGGCTGCACCGAGCACGGGGGCGTTCCGGGCAGTGCTCGGAGACGACGCAGAAGAGGCGATCGAATACCCTCGTTTCCTGCTCCCCATCCCCGATGGCTGGCTTCTTTCCTCAGAAAGTCCGGGTTGCCTTTCGACCTTTGACTCGAAATGGCGGCACCGTGCCCAGCTCGCGGTCCACCCCGCGGACTCGCCCCGGCCGGTCCACATGGCAGAACCGCCACGGGCGCTGTTCGCCACGGCGGACTTCCTGTATGTCCCGGACTTCATGAGAGGAGTGGTGTATGTCGCCCGGCAGACTGGACAGCCGTAGGTTCTTTGATGCGGCCTATACACGCCGGTTCCTTCGTGAAGAGCTGACCACCGTTGATGGTAAGGCTGACGCTTATGCCGTAGAGGCTCGCTTCCGTCAGACGCTTTACGCCTGCGCCCAAGCCACCCATGCCGACGACAGCGGGCTGGGTATGCAGATCCGTCAAGTCGGCCTCGGCATGTTCCGGCCAGACGCGATCGCCGCCGGGAAGGCCGTACCCACTCTCGAGTATCTGCGTCGGTTCGACTGCCACCCGTACGCATACTTCCCGGTTCAGATCACCGCGAAGGAGTACGAGGAGATCTGGAGATACCAGCTCAACGTGGCATCCGGTGAGCGACTGGCGCTACTCGATCTGATGTTCTCGTGGTCGCAGTCCATCCTGGTCCAGTTCCGCCGCACCGCGGCGGTGATAGACGTACCGGTCACCGTGCTGATGGCAGACGTCAAGGGGCCTGCGGATCCGGTGAACCGCGAAGGCTGGGAACTCCGCGCACACCTTGCCAGCCCCAGTCGGGTGGAGACCTACTTCCACACCGCCGACGAACCGGCGGACGTGGTGCGCGACGGCGGACTTCTCCTCGGCGCGCGAAGGTTCGCAGAAATGCTGGCCGAACCCTGCGATGAAGCGCGCGACGTCGCAGGCGCCATCGCCCGCCTCGCCTCGACGATCGCCACCGATGCTCGTGCGGCGGAGGCCACATCCGACGCGACCGTCTCGCCCGGCATCGTAGATCCAGATCCCCTCGTGGAGATCGACCTTGCCAAAAGCCGGCGAGTCGACACCTGGCAGATCATCAGGCATTTCGGCGCCGCGTGCGAGATGTACAGCGGACCAGGTCGGCCCACCATCTGGCAGGCAGGCTCTGACGGATGGTGGAACCGTGTCGGGCTGCTCGCAGATCGGGACAAGTGGCTGACAGCAACTGCCCTGGGGGATGGGACGGATCAGCGTTGACAACACCGGTGCTTGTCTTCGATCTAGGCGGAACGTGGTTTCGAGTCGGCCTTTCGCACATCGACGGAAGCGTCACTCTGCTGGGCAGGTATCCTGCCATCAGTCGTGCGACACATCCGGAACTGCCGGTGGCCGAACTGCAGCAACGAATGGTCTCGTTCATCGTCGACGAATGTGTCCGACATGCGTCGACTGACGTGGGAATCTCCATCGGCGCCGCAGTCAACGGTCACACCGGCCTGGTCCTGAGCAGCGCGCCCCTGTGGGGGCCCGGTACCTGGGAGCTGCCGCTGACGCAGAAGCTGTGTGAAGCGCTTCCCGCGGTTCGGTACTCGGTGGTCAACGACGTTTCGGCACAGGCACTGTCGCTGCTGGACGAAACGGCCTCAAGTGACTCCATGGCGGCAGCGCTCACCGTCAGCTCCGGCATCGCATACCGCACGATAGATCTCGCCTCCGGCCATATCCCTCTCGATCCCGACCACGGGGTTCAAGGCGAGATCGGGCACCTGCCGAGCGCTTTCCCTTGGCGTGGGACCTATCTCAGCGCCGTGTGCGAATGCGGCGTTCAGGACCATGTGAGCGCGTTTTCCTCCGGCCGGGCGATCGAGCAGTTGTTGCCTCGACTGGCTGGACCCGACTGGAACATCGCCGCCTTCGGGGAAGCGTGTCGAAGCGGTGACGCACTGGCCCTGGAGCTGCTTGACGCCTTCACTCTCCCGCTCAGCACGGTCCTGCTGTATCAGGCCACGCTGAATCCACAGGTTCGGCACACGGTACTGCTCGGCGGCGTAGTCGACGAACTCGGCGAAATCTACCGGGACAGCGTTCTGAAGAACCTTGCACGGCTGGGGTTGTACGAGGTCACGTCCCGTGACTCTGGATATTTTGATCGACGTATCAAAATCGGAAATGGCGACGGACTCGAGGCATTGAAAGGGGCGGGGTTATACGCCCGAAGGAACGGGAGGGCGATTCAATGAAAACCTGGGACGTCAAGTACACCCATGAGGTGAGCTATCGGGTGGCCGTCACGAGCGACGTGTTCTCGCCGCGCAACGAGGCCTTGGCGGACGCCGCCGGCCTCCGCGGCGACGCGCGCCGACTCGTTGTGGTTGACGCGAATGTGCAAGACCTTTGGGGAGAGCAGATCCGGGCATATTTCTCCGCGCGAGGAGTTGCTGCCACGGTCTTCCGCATGCAGGCGGGAGAGGATGCGAAGACCAGCGCGACGGCACTTGCCGTCGCAGCGGCCGCGGACGAGGTCGGCATCAGGCGTCGGGATCCCATCATCGCGGTCGGTGGGGGGGGTCGTGACCGACACCGTGGGTCTGGCGGCGAGCCTCTACCGCCGAGGAACCCCATATGTCCGGATTCCGACCACGCTGGTCGGGATGATCGACGCTGCCATCGGAGCGAAGACCGGCATCAACGTGGGTGAGCACAAGAATCGCCTCGGAACGTACTACCCGGCTACGAACACGTTGGTAGACCCCCAGTTCCTCCGAACGTTGCCGGCTCGGCATGTGCGCAATGGCATGGCCGAGATCATCAAGATGGCGATCGTGAAGGAGCCCGTCCTGTTCAAGCTTCTCGAAAGCGATCCAGAGGGTTTGATCGCCGCGCAGTTGGTCAGCGATGACGGCCAAGAGATCATGAACCGAGCCATCACCAGTATGCTGGAGGAGCTCGAGCCGAATCTCTGGGAGAACGAGCTGCGACGACTCGTCGATTTCGGTCATACCTTCAGCCCGCGGCTGGAGATGTGCGCCAAACCTCCACTGCTGCACGGCGAAGCTGTTGCCATCGACATGGCACTTTGCTGCGCACTGGCATACGGACGCGGTCTGATCTCGGCCACCGACGTGAAGCGCATACTGAACCTGCTGCACCGGTACTCCCTTCCGATCACGCACCCGACATGCGATGTCGACCTACTTCAGGAAGGTCTTGAAGAGTCGACCCGGCACCGAAACGGTAATCAGTACTGCCCGCTTCCCGTCGGCATCGGCGCCGCCGAATTCGTTGAGGGTGTGACCAATGCCGAGCTCGCGCGCGCGGGCGAGTTGCTCGCCATGTTCGCCCAGGCGGAAGAGGCCCAGGTATGACCGGCGACGGACGGCATGAGAACGCAGCGCTTGTCCGCGAAAACGGAGGCTTAACCCTGCGATTCGCTGGCTCGTGCAATCCTGAAGCGATTCAGATCCTCCGAGCCGGCGTATGCGGAACAGACCTGCAGATACTACGGAATGCGCGGCCCGACGCTGCCCGGATCCTTGGTCATGAAGGGCTCGGAATACTCCCGGACGAGCGACGCTACGTCTTGTTCAATCCGGTTGACCCCGATGACCAGGATCGCATCCTCGGGCACAGCTACGATGGTATCCACCAGCGTTATCTCGATGCCCCGGGGAGGCCGCCTCTGGTGTCGGCTGCGCCGAACCTGCCTGCCGATCTAGCCGTCCTCGTGGAACCGCTGGCGGCAGTGCTTTATGGGTGGGAACTCGCGGCACCCCGCTCCTCGGTAGGGATCTGGGGCGCTGGCACGACCGGAGTGCTTGTCGCCCTGGTCGCAGAGATTCGTGGCGTCCGTGCTCACCTAATTCATCGCCGTACCGACCGGCTGGCCTTTCTGCGCTCCACTGTGCAGCTGCTGTCCACACAGACGTCGACGAAGTTGGATCAACGTCGTGCGGCCCGCCTTGACGGTGCGTTCATCTGCCTACCGAGAGAAGGTGCTCACGGCGCGCTGGCCGACGCATTGGACGCTGTCGGGGACAACGCCACGATTGACCTACTGGGCGGGTTCGGCACCAACGACCGGCACCCCGACCTGCCCGGTGTGGATCTGGGTCAGATCCGCCGATCCAACGTGTGTGGCTCGCCGGTACTCGGCGCTGTGACCCCTGCACGGACTCGTGGTGGTAAGCAGGTGTCGCTTACCGGCCATCGAGGAACGTCAGCGGCACACATGGCTGAGGCTCAGGACCTGCTCATCGAACACGCCGAACGGTTCGGCGCATTGATTACACACGTGCTCGCACTGGACGTCGCAGGCCTCGAAGTCGAGCGCATGGCTCGTGGCGGGACGCGCCCAAGCGGCCGCGCCGAGTACATCAAGGTGGCAATTGATCCGACGATGCCCGACGGCTCTCGTCGGAGGCCAGACTGGACAACGACCATCGAGGATTTGAAGTAGGTGGCATGACGACACCTGCCAGTAAGCCGAGCGAACGGCTCTGCTGCACCGATAGGTGACATCTGAGTACAGCGCGTTCGGCCTGAGCGCCGGGTTGCTCACCGTGGACATGTTCGGTGTCGCTGCTGTGCTTGCAATCGCCGCGGGCCTATGTGTCTTCCGGCGGGCGGTCGTCAGGTCGCCACCCGGGCGGCCCCGGTTAGGGCGACGGCGACCGGCCGATCGGCCGAAATCGCCGGACCGGCGGTTGGCCTGTCGTAGCGGACCGGAGGATCGCTACGAGGTGACGCAGACCAGCGGCTCAAATTTCCTCGTGTTCCCTTTCACAGATCAATATCAGCTTTCCGTTACTGTATGTACACAGCGGGCGTTGGATATTCCGGCACCGGCCTTCTAAAAGCACCTAACACGATCTGTTGAATCGATGTTCATCAGCGTTGCGGAGTGAGGATCAGTCTCGTTCCGGTCTTCGTGAGCAAGGCCTGGGTCGTCGATGACGAGTTGTGGAAGCTGATCGAGCCGGTGCTGCCTGCTTGGCCAGCGAGGGCGCCGGGACCGCGGCCGGTGCCGGACCGGCTGTGCTTGCAGGGCATCCTGTTCGTCCTGCACACCGGGATCGGCTGGGAGGACCTGCCGCAGGAGCTCGGGTTCGGCTCGGGGATGACCTGCTGGCGCAGGCTGCAGCGGTGGACCGAGGCAGGCGTGTTCGACCAGGTCCACCAGATACTGCTGGACAAGCTGAACGCGGCGAACCGGATCGACTGGTCGAGAGCGGCGATTGACGCCAGTCACATCGACGCTAAAAAGGGGGTGCCGGGACAGGCCCGTCGCCGGTCAACCGGGGCAAGCCCGGCTCCAAGCACCACCTGATCTGCGACGGCAACGGCACCCCGATCTACGTGCTGACCAGCGGCGCGAACGTACCTGACATCAAACGTGCCCTGGATCTGCTCGACTGCTACCCGCCGATCGCCGGCAGGCTGGGCCGGCCTCGGCGCCGGTTCGCGGCGCTGCTGGCTGACAAGGCCTACAGCAGTGCGGCGTTCCGCCAGGCCTGCCGTGAACGTGGCACCGAACCCCTCATCCCCAAACCGAAGGCCACCGGGATCAAGGGCCTCGGCAAGCTCCGGTACGTCGTCGAGCAGACCTTCGCTCTGCTGCATCAGTTCCGCCGATTGGCTGTTCGCTGGGAGCGCCGCCTCGACATCCACGACGGCTTCGTCAGCCTTGCCTGCGTCCTGATCTGCTGGCGCAGATTGATCAATTGGACCGATCAGAGATCGTGTTAGGAGTTTTAAATCAGGCAGCCATGACCGCAACATTCACTCAACGTGACCGACCGGATTCCGGAACAACCCGGTGGGCTGGGCTATTAAGGAAGAGCGGCGGGCACGTGCTCGCCGGTCGTGTCGATCGGACCACGCCGAGCCCTGCCCCGGTCCGGCCGCACGAACCCGCATGACGAGTCATGAGGCAATCGGGGGCAGGGACGGGGGAACCATCATCGGTCCTCGACCGGCACGCCGTACTGCGGCGCCCGGGACGTGAGGACCTTGGGGTGAAGCCGCCAGTGTGCGGCCGGGCAACCTTCGCGCCCGAATCCGACAGCTAACCTCGCAGGCGTGCCGGAGGGATTCCTTCACCGTGCGCGTAAGCACTTCGAGCCGACCCGCCCGTACCCTGGGAGCCGGCACTATCGCCCTGTCCGTGGGTCTCGGTCTTCTCACCGGTCTCCTCGACACACCGCAGTCGGCCTCCGCCGCGACCAGGTCGCCGGCCGTCACCACCACGCAGGTGTTCTCACAGACAAGCGTGCCATTCAGCCAGAGCGGCCTCACCCTCAAGGCGGTGGCGTCCCAGTCCAAGGCGGCAGTGTCCCGGGCGGCCGCGAACCGGATCATGATCGAAGCGGCCAAGCACAAGGGCAAGCTGTACAAGTTCGGCGCCGCCGGGCCCAAGCGGTTCGACTGCTCGGGCTACACCATGTACGTCTACAAGAAGGCGGCGGGCAAGAAGCTGCCGCACAAGGCGAACCTGCAGCAGCGGTACGGCAAGGCCATCGCCAAGTCCCGGGCCCGCCCCGGTGACCTGATCATCATCCGTGACGGCTCGTACGGCACGCACGCCGGCATCTACGCCGGTGGCGGCATGATGTGGGCCGCCCCGCGGGCCGGCAAGACGGTCACCAAGCAGAAGATCTGGAGTAGGAACTACGTGGTCCGGCGCCTGGTCTGAGTCGGTCCACCCGGCTGCCTGCGCTTCGCGTCCGGGCATCACACAGCGCCGCCTGCACCCGTCTCGGTCGGGCGCAGGCGGCGCTGTCGTACGACCTGATTCGTGATGCTGGTGAGTCCGCGCTCAGCGCAAGGGGATGTCGGTGGTGTCGTGGGCCGGCCTGGGGCCGTGGATGCGTCGCTGGTCGGGGTTGATCGCCACGTCGTTGATGCTGGCTTCGCGACGACTCATGTATCCATGCTCGTCGAATTCCCACTGTTCGTTGCCGTAGCTGCGCCACCATTGGCCGCTGGGGTCGTGCCATTCGTACTGGAACCGCACGGCGATGCGGTTGTCGTGGAAGGCCCAAAGTTGCTTGCGCAGGGCGTAGTCCAGTTCGCGTCTCCACTTATGGGTCAGGAACGCTTCAATCTCGGCGCGGCCGGTCAGAAAGGTGTCGCGGTTGCGCCACATGCTGTCGGGGGTGTACGCGGCGGCGACGCGTCGGGGGTCACGGGTGTTCCAGGCGTCCTCGGCGGCCTGGACTTTGGCGCGGGCGGTGTCGACAGTGAAGGGTGGCAGCGGATGCCGTGGGGGTTGCGGCGTGCTGGATGGGTCTCTGGTCATGAGGTCTCCTGGGACGGGTGCTGCTGGAAGCGGTTTCGGCGAACCATGTCGCGCAGGGCGTCATTCTCCGCCTGGAGCTGGGTGAGCTGGTCACGGATCGGCGCGAGAGCGTCGTGCAGTTCGGCTTCGTTCCAGCGTGGCGTGATGTGTTGCGGGCAGTTCCAGTCGTAGCTGTGGACCTCGACGGTGATGAGCCGTTCCACCACGCCGGGCGTGCGGAGGGTGCCGAACCTGCCGGCGAGGTGGGCCGGCATGCCGTCGCGGATGTCGTGGACGGTTGCCGTTCCCAGGATCTTGAGTCGTCGACGGTGGGCGTAGTCCATCAGGAACAGGGACACCCGCGGTGAGCAGCCCAGGTTGCCGACGGACAGGTACTGCCGGTTACCGCGAACGTCGGCCCAGGCCAGGACGCTGTGCCCGGCGACCGGGTCAAGCGGGTGCAGGAAGCCCGGTGGGCCGCCGCGGTACTGCAGGTAGGGCCAGCCGTCGGTGTTGACGGTGGCGAGGTAGAAGCCGTCGCGGGCGGTGATGAACGTGATCTCGTCGGCGCCGAGCAGGGCGTCGGTGTCCCAGCCGGCGATCATGCGCTCGATGGCGGCACGGCTGCCGTAGCGCTGTTGGGCGGCGGCAACCGGCGCGGTCGTCAGGTGCTGAAGGTAGTGGTGCGGCATCGTCGGCGTCCCCTCGGGCCGTTCAGATACGCGGCGCCCGGCAGCCGCGGAGCGGGTCGTGCCGGCGCGGCGCGTCCGGTCAGATCAGGGTGCGGGTGAGGAGGAGGCACCGACACGGTCACCATCCGCGGTCCGGCCAGCTGTCCGGCATCCTCCACCCCTAACCACTGAAATAGGTTTTAGTGGTTAGAAGCTAGATCGCTTTCGTCTTACCTGTCAACTGCACTACGCCGGTAAGATGGATGAGTGACGGCACGACCATTGACCGGCGAACCGCTGGCCCTGGACCTGGTGAACACTGAGTGGGTCGACCATGGCCGCACGGTGGACCTCTTCGACGAGCCCGGCGGACTGCTGGCATGGCTCCACGAGCAGCACCTGACCGGCAACCACACCACCGTCGCGGCACCCCTGCGACAGGCCCGATCGGCGCTGCGGCAAGCTCTTGAACAACCCGACGAGCACGCCGAACAGCAGCTCAACGCGATCCTGGCGCGCGGCGTCGTGCGGTACACGCTGCACCAGGGCGCCGTGCGTGAGGGCTCGGACGTCGACGCCGACTGGTCTGCCGCCTGGCACGCCGTCCGTAATTACCTAGACCTGATACGCCAGGATCCCACCCGGATCCGGCGCTGCGCCCACCCCGCCTGTGTCCTCTACTTCTTTGACATCTCCCGCAACGGCACCCGCCGCTGGTGCTCCATGGACGGCTGCGGCAGCCGCGCCAAAGCCGCCCGTCACTACCAACGCCACCGGACAACACCCGGCTGACCCCTCGGCCACGCCCTCCGGATAACGCCATGCCACGTCTTGGACAAGACCTCAACCTGCCCCCCGACGGATACGCGACCGGGTCCAAGATTCACCGCCTGGAGTACCCGCGCAAGGCCGCATGACGAGGAAGCTAGCTTTCAGCGCCCCAGACCTGCAGGCTGCCGCCAGTGTCCAGGCCGCTGCGAGTGAGAACGCTGCCGTTGGTGGCCTGATAGGTGGTGAGGGTTCCGGTCTGCGGGTTGGTGATCAGAAGCCGGGATCCGGACCACACGGCCGGCATGTCGTCCTGAGTGTCTTGCCGGTGGACAGGTCGTGGCGTTCCAGCCGGTAGCGGGTTGTGCCTGCGGCGGTGCCGTCGATCGCGGGACACGGCGGCTGGTTCAGCGATTCGGTGACGGCCCAGCCGCCGGTCAGCGCAGTGTCGGGGAACCAATCGCTGGCCGGCGCGACGGTCCGCGGTCGGTCGGCATGCGCGGGGTCCAAGGCAACCAACCGTCCTGCGCGCAGACCGGCGATGGTGTGTGCGGCGAGCTGCCGCACCTTGGTCATGGCGAGCGGGTCCGCGCTGGTACCGCCCGTGTCTTGCTCGGTGACCTGTCGGACGGTGCCGGTGGTGGTGTCATCGAGCACCTCGACGACACCACCACGGTTCACCACGATGCCGTGAGGTGCGCCGGCCAAGGTTGCTACCGGGCCACCGGCCTGCCCGCAGGCGGCGGACAACGCGGCCGCAGAGCCAACCGTGAGCATGGTCCGGACGTAAGACTTAGGGCGACGTCTCATCGGCATGAAGGCCTTCCCTTACGACTTGGAGGCACGAACATTTGTGGTGGGTCCCGGCCGGCCTCGACCCGGATCCGCGGGCGTCGCCAGTGCACGTAGTCGCAGACAGCGGCATACGAGATGCCTTCCATCTCCTCCTCGGCCAGCAGCCGATCATAGATCCGCTTCACCGTGCGCCGTTGTTTGCGCGGTGCATCGAATTCGGTCAACGGCATGACGTCGATCGCCGGTTTGAACGGGTCCAACCGCGACTTACGCGGCGGCAACTTTCTCCGCGGTGCCGGCCAGGCCGAACTCGGCGCTTCGCGAACTGTCCGCCGGTGCCCGCCGTGTTTGGCCGCGAGCGACCGGATCGACAGCCCTTCCAGCCGCGAGTCCGGGCGGACGGCCGCGGCCCATGGCAGGCTCGCTCACGTCGGAGCAAACCGATCCCCTCACCGCTCCGCCGCGGGGTGGGCCAAGACTCGGCTCTGGCGCCGAAAGCGTGATTGATCTAGGAGTTCAGTATCCGTGGCACCTCGCCACCACTTCCCGTGCTGCGTTCGCCGCGCTGTGGGTGGATGGTCCAGACTACGTGGATGGGTGATCACTTGGCGGACGCTGAGCCGCAGCTCGCGGAACTCACGGATCACCAGCGAAGACTACGAAGACGCTTCCTGCAGTCACGGGTTGTTTCCGTGCCTCAACCGTGGCGGCCCGCGAAGACGCCGTGCACCTCGGTCGGGGGCCTGCAGGGCGTCGGCTTCGCCGCGGACCCGGCCAGCCGCAGGGATCTATTGCTGGTGACCTCCTCCGACGGGCACGGCTTGTTCGATGCCGTCAGCGGGCAGAAGCTGGCTCGAGACCGGGACCTCGACCCCGGCGTGCCCTGCCCGGACGGAGACCTGTGCTGTCCTGGGCTGGGTCCGATCGCGGCGACGTCTGTGCGGATCGCCGGATTGCACGGCGGCGGGTTGCACACCGGCACCCGTGACGGCTGGCTGATCGACGTCGTCAGTCCCGACTGGCCGAACCAGCGTGTTCTGCTCTCCTACAGGAGTGACCCCTTCAGCGGCGAGGAGGGCGCCACGTGGTGGCACATTTTCCACTCGAGATTTTCGGAGCTTCGAGCGGCCGGCTTCTCGCCCTCCGGTAGCACCTTGGTGGTCGCCACCAGCAGCGACATCACCGTCTGGACGAGGGAGCGGCCGCCAGTCGCCTGAACTCGACCACCCAACGGGACGCCTCGGCGGAGCAGGCCGAATCGAGCCTCTCGTACATCTGCCGTCACACAGTCGCGCGAGAGCTGAGTTCGAGCACCAGATGCTCGGGACTTTCCACCGATGTGCCCTCAGCGCTCCTGGCACGCTTGCTTGATGAGTGCATGCTGACCGTATGACCGACGGCGTCTGGATCGTAGTTGCGGTCGCGCTGCCGTCATTGATCGCGGTGGCCGCTCAGCCTGTTATTGCTGCGACGGCGAGCCGCGGGAACACGGCCGGCCGAAGAGGTCAGCGCCCGACGCGGGGACAAGGCCATCCGCGCGTTGGACCGTCGCCGTCGTAAGGCCGCCCGTGGTGACCTGAGGGGTAAGGGTGGGGGCGGCGACTTCAAGACGGCGTCGGATGCCGCGTTCGCGTCCGACACCACGATGGGTGCGTAGCCGTACCGATGCCGCAGACAAGGCGTGGGATGACGTCGACACCTCAGGCGCTCGCCCGCGTCTTCGGCGAGCTGGACCACCACGCGAACGGCTCGTCGCCTGGTCGCCGGGCATCGCGGTCAAATACCCGCAGACCCTCGACGGCCTGCTGCGGGTGCTGCCCGCCGGCATGGAACTGCCGCCCTCGACAGCGAGGCGGGCGCCGACCAGCTGCAGGGGCCCTTACCCGGTGGTTCAGCGCCCTGGCGCCGCCCTGTTCCGCCTCGACGTGCAGCTGCTCGAGAAGATCCTGTGGCGAGTGCTCTACGGCGCCGCCGTCCGCGCCGAGGAGATCCTCACCCCTCGACATCGGCGACCTCGAACTGCCCAACAAACGCGCCAAGGTGCACGGCAAAGGCGGCCGCATCGAATGGGTCCGCGTTGAGTGGATCAGTGAGCCTTTTTCATCGTGCGTAGCGGCCGGCTTCGACATGGTGCAGGACGCGAGGATGGCCTGCACAATCGCGGTCGCGCGGCGCGGGCAGCAGCGCAGCTTGGCCAAGATCTTCCAGGTCTTGAGCGTGGCGATCGCCCGCTCGCCGCGGGCGCGGATCTTCGCGTGTGCCCGGTTGACCGCCTTCTGCCGGCGTGACAGCTTCGGCCGGAATCGGCGCCGCTTGAACGGAGTGCGCACGCTGCCGCGAGCGCTCTGATAGCCCTAATGGAGTCAGAGCGGCCAGGAGCATGGGATTCAGCTGCTCCATCAGGGCGATCACCGTCTCGGGCGCCCGAGACGCCAGCTGGTCCGCGGCCCGCTGAACGGAGACGCCTGCCAGCTCCCGCCACAGCTGCTCCAACACCTCTTGGTCCGGGGCCGTACTGAATCCTGGGCGGCCGGGTCCGAGGCGTTGGCGGCAGCCGGTGATGCTTCGAGGGCTTCCCGGAGCTCCTCGACGGTCCAGCCGTCGGAGGCCAGCATCCCGGCGACCTAGTGAGCGAGGGACGCGACGCGGCCGCGGGCGCGCTTGCGCTGCGCTTCGGTGTCGCAGAGCTTCCAGGGCAGCGCGTCGACGACGAGGTCGGCTTTGGGCAGGTGGCCCTTGATGTCCGGTGGGCGAGATCCCCGGTGGTGAGGTTTGTCGCCCGCATGGACTCGGTGTCCTGGGGCCGGTTCCGTCGTTGGCGTAGACGTCAGACCCCCCCGATAGCAAGGACGTGAAATGAGCATTTGGCAGAGTTCCCTCGAAGGCGGCAGCGGATGTCTCGACCTCGGTCGCGGTTTGTTCGGCGGCGGGGACACGAGCATCGGCCCCGGGCAGCAGCACAACGGAGGATGGGGTGGCGCCGATGACTGCGGCGACGACGCCGACGGCGACCACGGCTGGGTCGGTCACGGCGGCCACCCGGGCCAGGGCAGCTTCGACGACTGCGACCCGGGCCGGGGCAGCTCCGACGACTGCGACCCGGGCCGGGGCGGCAACGGTTCGATGGGCCACGACCACCACATGATCCCGTTCTGCCACTGACGACGTGCGCTGACAGCCGGCGGCAACGGGCCGCCGGCTGCCGGCCGGGCACCGGCACTTGACGGAGGCTGCGATGACCCCGCCGAGCGGCCTGAGCATTCAGGACGACCTTCTGGACGTGATCCAGAAGGTGCTGCAGGGAGCCGCCGCCAACCTACGCCCCGATCTGGAACGCCGGATGCGCCTGGCCGCCGCGGAGCTGGCCGGCGGGGGCTCCACGATGATCGTCGCGGAAGCGGTGATGGACGCCCTGCAGTTGCTGGAAGTCGATCTTCGGAGCCGGCGTGCGGCGATGGCCGACCCCCGCCGCCGGGCGTGCCTCGCCTTCGAGGCGCGTGACGACGAGGGCCGCCTTCGCGCGTTTCAGGCACAAGCCGGCAAATGGCCACGGGCACTCAGCGACGCGTTGTCGGCGACCATGTCGGACATCGAGTTCGCCGTGCACAACTGGTTGCGAGCCCTGCTCGATGAGGGCATCGCGGTGATCGAGTCACAAGGGCTGGCCGGCGCCGACCTCGACGGCTGGCTGCGACAGCGCCTCGTGGTCGAGACCGAAGCGGTACATCGGGCGTTGCACGTGGCCGCGCGCGAGATCGGCGAGCGGGTCGCCGCCTCGATCGGGGTGAGCGAGGCCGTGCCGCCGGTGCATCTCGACCTCGAACCGCCGGCGGAGCTGGTCGCCCACATCCGCCGCGGCCCACGGGTGCTGTCTGAGCGGCAGACGATGGCCACCCGTCTGGTCGGCGTACTCATGCCAGCCTACAGCGGCATCATGATCGCCCTCATCGTTCCCCGGTTCCTCGGCCTCGCGATGCCGTACTGGCTGTCCACGGCCGTTGCGGCGTCCGGTGCGATCGCCTTGGGCGGGACCGCCCTAGCCGGGGAGAAGCAGCGGCAGCGCAGCCGGCGCAACAGCGAGAGCGCCGCCGAGCTGAGGTCGCTCATCGACACCTTCCGGATGGCCGTCGGCAAGCGGGCACGCGACGGGATCCGCGCCATCGAGCGGCAGATGCAGGCCGGGTTGAGCGAGGCGGTGACCGACCAGTCCCAGCGGCTGCTCGCAGTCGCCGAGGCGTCGCGACGTTCGGCTCAGGCGGGCGAGCAGCCGGAGCAGGCCCTGGCCGCCATCGATATCGACCTCGCTTTCATCGGCGAGCTGCGAGAACGTACCCGACAACTCAGCCCTCCCCGCCAAGCGCTGCCCGCGCCCGGTGAGCAGACGATGGCCCTCGACGCCGTAGCACTCCCCAGCGCCTCGGGATCGCCCAGCCACCCCTGTCCCGCGCGACCAGCCGGCTCGAACGGCGGCTCGGCGTCACCCTGCTCGACCGCGACCACCACGGCGCCCGGCTGACCAAGGCCGGCGCGGTGGTAATGCCTGTCGGCGGAGATGGTAGCGCCGTCGCCTCGGTGCCCCAACCGAGTGCTGGCCGCGCGTCGAAAGCCCCCACCACCATCGGTGGGGTCTTCGTCAGTCGCATTCCCGGCATGGCCGTTCCACCAGCTACGACGTCGAATTTCTCGACATCCTCGATGTGGCCGACCTGGGCGCGCTGCCCAAAGGCCGCGCCGTGGTGCTGGCCTCCGGATCCGTGCCGACCCTGGTGCGCACCCTGCCGTGGATGAGCGGCCCGCACGCCGCGGCGGTCACCGCGTCGATCCGGGCCCACGACCCGGCCGCCGAGGACACGATCGCCGAGGCCCTGGAGTCGCTGCGCGAGGTCGAGCAACAGGAGGCGACCGCCGGCACCCCATGGACCTGCGCACCTACCTACGGCCGCTGCGGGCCGCCGTCGGCCGACCACCGGCGCCACGTCGGCCGCCGAAACCCGTCAGCTGACCAGCTGGCTGCTCACCCACCCCGACCGACTCGCTGAAGACGACCGCGAACAACTCGCACGAGCGCGCGGTGCCTGCCCACATCTGGACGCCCTGGCCACCCACGTCTCGGCGTTCGCCGAGATCTTGACCGCCCGAGACGGGCAGAGGCTCAACGACTGGATCGCCGCGGTCGTAGCCGACGACCAGCCTGACCTGCGATCCTTCACCGCCGGCCTGCGCCGTGACCACGACGCCGTCGTGAACGGGCTGACCATGACCTACAGCTCCGGAGTAGTCGAAGGGCACGTCAACCGCATCAAGATGATCAAGCGCCAGATGTACGGTCGCGCCAACCTCGATCTGCTACGCAAACGAATCCTTCTCGCCTAACGGGTCAATCCCGATCACGAAAAGTAGGTCAGATCCAGTTTTCACGCGCCGCCGACAGGATGCGCTGGCGAAAGCGAAAGCAGCCCGCGACGAGATCTGCCAGCTCACCGCAACCAGCATGCTGGGGCGTGACCGTGGACGCACCGATGATCCACCGTGAGGGCGAGATCCCCTGGATCCGAAACCTGATCTCTCGCTGCCGCGAATCGGAGACGGCACCCTTCCTGAAGCAACTCGGCTCGGTATGGGCGCAGCACACGGTCCACGCCGACGAGCCGATCGCAAAGCCGACAAGAACGGACACGACTGGACCCGCTGGGAAGTCAGCCTGCGCGTCCGTGAGCACCCACAGATTTCAGCCCGATTTCCGGCATAGCCCGACACCACCGGGTTCGCACATGGAGGAATGATGACCTTTCGTGACAAGTCCGTGATCCGACAACAGTCGAGTGACGACATCGATACGTTTCGTGGTGTGAAGAGTTCAGCGCCGACCACCGGCGAAGCCACCAACGCGGACTCTTCCACGTCCGTGGATGTGCCAACTACCTCACCCTCGGACGGCTTGAGCCGCGACCTCGCGCCGCCGTACGTTGCGCCGATGACCACCAGCGCCAGCTCTGTCATCACCGCCATCAACACCCGACGGCCGGGCCTGAAGCCCGCAAAACAGCACATGCTGATGTTTTTTATGCAGGGCCACCACCTTGCCTGGCGCGACCGGGCCCTGTTCGACGAGCCCATGCACGCCACCGAACGAGCCGTTGAGATCGACGCCAGCGCGGACAGCGCTGAGCCTCAGATCACGGACGAAGCAGCCCTGAACACCATCGGGTACGTCATCGCCCGGTACAGCGCACTGTCACCAGCCGACCTACGCACCCTCATCCAGGCATCGCAGCCGTGGCAGACAGCCACCAAACCGGGCTCCGAATCCCGCATCGAGTGGGCGCTCCTGCGCGACTGGTTCCAGCGCCCGGACGAGACCGACGACCCGGACGATGAGCGACCCAACCGTGCCGAGGTGGCCGCAGCCGAGGCCTACCTGGCGTCTCGCGCCCGGAAGTAATCACTGACAGCAGGGGGTATGCGTGGCTGGTCAAGCTGGCACTCCGGTCGAATGGGACCTCGAACAGTTCAAGGTTGAAGCCCCACGCTGGCGTGACGCCGTGCATCCCCCTGCAGAGATTTACATCAAGGTCGAAAGATGGTGGCGGCTGCTGAAACGCGTCGACGCCCGTATCGAGGCTGTCCCGGTCCGCCCGGAGAACAATCCCGAGGGCAACCTGTGGTGGATGTGGGTACCCGACGTCGAATGGGAGGACGAGCACGGACGAGGGTTCCGGCTTTCGTGCTACTTCCGCGTGTACGAGAAAGACGATCCTCCACGCCTGGTCTGTGACGAGTTCCGCAGCGAGCGGACGAGGTAAGCACTCCCTCTAAGTGATCTAGACTCGGCGGGTTCCGACCACCCCCTAAGGAGGCGCTTGTGCAGCTGACCGAAGTACTCGACGTGCTTAAGCGCCTCATCGAAGCAGCCGAACACCCCGATATCACCGAGGTCAGCGTGTTCTCCCGCGGCCCCGAACTCCCGCGCAACGGCATCGCCGTGAAAGACCGCTGGTCCGGCGCGTAATTGTCCTTTGCCAGGACAGTTGAGGCAGCGGCGGGCCGCTGAGCTGAGCTGCCTCATTTTGAGTGGCAAGCAACGGAGTCCGGTTCGCCGTTGAAGATGAAGTAACTCGCAGGATTTTGGTCAGGACGGGAGCCGCTGAAGGCGTCAATCGACCGTGTGCTCGCGGCGGTCGGGGCGGATGACGATGGTGCTGACGGTGCCGTTGCCCCAGACGGTCGTGTTGAGCATCGCCTTGTGGTCGGTGGAGAGCATGGAGAACTCCGGCACGAACCGATCGGTGAACAGCCCTCCGAAGCCGCTTCGCAGGGCGGTCGAGTGGCCTCCGGCCAGATCCCAATGGTCCGACAGCCGGACCCTGACCCAGGCGTACTCGGGTTCGACCTCTTCAGGGTCGCTGTAGTTGACGTTGAGAAGGAACTCACGACGGCTGTCGAGGACGCCGTATTCGGTAGCCATGTGCAGCCAGCCAGCGTTGACCTTCGCCGGCATCTCGGGGTCTTCGACGTCGACCATCTCGTCCGAGTCGAACCTTCCGTGCTCTGGTCCGCAACTGGCCGGTGAGTAGTAAGGCGGAGCAGGTGGCAGCGGCAAGCTGACCTCATCGCTGACCCGCTCCAAGAACTCAAGTCCCGCTGGAACGAGGTCCGCCGCGACGGCGGCATCGGTAACTGACACGAGCGGGATGGTAGCTGACCGCTAATCCAATCAATGGACCGAGAGATCACCGGTCACATCGGTTGGTCATTGACACTCGTTCGTGCCTCACCTATCCGGCAGAACCACCTGGATGCCTTACATCAAGTGGCAGTACCTCATCCCGGATGGCCAAGGACAGTAATGCGACGACCGTTAGAACCGAAGCCGTCCGGGCGGGGCCGCCGTTGGCCGTTAAAAGCACATCAGGAGGGTCTGGGGTGCGACGTGTTCGCAGTCTGGCTGCGGCGAGGGTTCCGGCCTGCCATGCTGCGCCGATCGACGCTGCGGTCGGTGCGGCTTCAGCGGGGTCCCACAGGTGATGCCCGGCGTAGAGCAGCAACCATCCGTTCCGGGTGACCGCCGTTCGCCAGGCAGGGGTGTAAGTAGTCACCCCGTCGATACAACCGGCTTCTCCGGGCGAGACGATCCGGATACGGGCGCGCATGGGGCCAGCTGGTCCGATGGTGCCCGGCCAATCCAGCAGGGGCCGGGCTGGCTGGTTGAGATCCACCTCGGTGGTCGTGCCATAGGCGACCGAGGGTGGATAGCAGTGTGGTGCTGAGCCGCCGCCGGCCGCTGGGTAGCGTCCCTGCGCCCCTACCCGGACGACGGCGTGGCCTGCCCGCAATTGGTGCTGGCCGCCGCCGCCGAGCCCGGCCCAGTCCGGGCCGCCGCCCGGCAGTGGCAGATCTCCGCGAACACCCTGACCCTGCAGCACGACCGGATCCGCACCGGCACCCACAGCGCGGCCGCCACGGCGTTCCCGCCGCTGGCCCCGGCACCCGCCCCCCGCCAGGCACCACAGGCACCGCCTTCCAGCCGGCAACCGTATGGGAGGAGGCATCTACCGCAGCGTCTCGGTGATCAGCGCCGCTGGCCCTCCACGGCTAAGGGATGCAGTACCACTACGCAACTTCTTGCAGACCTTGAAAATGCAAGGCATCAGAAAAGGCGAGCCGCATACCGCCGGCACGCCACGAACGCCTAGCGGCTGAACAGCAGAAAGCCGAGGAGGGGACCCTAGGACGTCCGGCCGCGCGCGTACCGCGTCGCACGCCACCCATCTATGGATCGGCGCTTCGACGGTAGTTAGTGTGACGTCGACTGAAAGTTTTGCTCTGGACTTGCAAAGATCATCCTGAACGCCCAAAGTGGTCAGTGCCCCTCCACGCGGGATCGATGTAGACCTCGCCGGCGCGACCGGTCCACCCCATAGGAGGTCCAGTCAGGCACGACAAATGCGGCAACGACGCCCTCCGCTCCAGCGCCGAACCCGGACGCTCACCCCGAAGAAAGAGAGACACAGAACCATGTCCCGAATGACCCGCAGCGCGGTCCGAGGAATCCTCGCGACCCTGATGGTGCTTCTCGGCGCCGTCGCGACGCTCATGACGTCGCCGACCGCAGCCAGCGCCTCACCAATCGGCGCCACCGAGCTAGGCGCCGTGGACCTGGGCGGCTACTGCCGCTCACAAGGCAACGTGGACGCCGTGCTGTCCGGCGGCACCGCTTACGACTGGCACTGCCGCACCCGGGATGGCCAGAACACGGACCTGTCGTTCACGAAGGCATGCCAGTGGACCTACCCCGGTGAATTGCCCGGTTCCGCGGCCTTCGTCTTCGACCGGATCGACAACTTCTACGCCCCGGCGTCGGTGCAGTGCTGGAAGGCCAGCACGGATGAGGTCACCGCGCCGGCTCTCGACGGCTACTGCTCGCATCACCCGACGGGCGACCGTGCGGTGCTGACCGGCAATACCGTCTACGACTGGAAGTGCGAGTCGCAAAGCCCCAACGGGCCGGTCTACTCCCCCGTGAACGTGCTCCAGGCCTGCCAGCAGACCAAGATGCGCAACAGCGCCGTCGACCGCTTCACCAACTTCTACGACCCGTACTCCTGGCAGTGCCGGGTGTAACCAGGAAGGCTGCCACGTAGTTTCCTGTTTAGAGTCAACAGCAACGCTGGTCAATCGCTTGATAGCCCGAGCGACACACCGCTCGGCGCGCGACTCTGACCAGCGTTGCTGTTAGCTTTTCGGCCCGGAGTTCGGCTTCGACGGTGGCGAGCGTCTGCTGATCCTCTGCGCGCCGTATGCCATATCGCCCGCAGGCCAGCTTGCATAACGCTGCGTGACGCGAAAGCGGGCGGTCGCGACGAACTTGCAACAGTCAAATACGCGATCCTTCCAGTACCGACAGCGACGCGTGCGAGCCGGGACGTTACGGGCGGCCGTCGTGGCCGCCAATCCTTGCCCGTCGGAATCCGCAGGGCGCGGGGCGTCATGCTCGCGCGCCCCTTGCCGCGGTGACGGTGGTCGCCGCCGCGCTATCGGGCCGGCGGGCAGTCGGGCGGGAAGTCGGGCGGGCACGCTCAACCAATACTCGCTACTTTGCCAACTCGCCGATTAGGTTCATCACAATCGACTGTAAAAGCTCCTAACACGATCTTTTAGCGGGTCCAGTTAATCACTCGGCGCCAGCAGATCAGGACACAGGCGAGGCTGACCAGGCCGTCGTGGATGTCGAGTCGGCGTTCCCACCGCACCGCGAGCCGGCGGAACTGGTGCAGCAGGGCGAAGGTCTGTTCGACGACGTAACGCAGCTTTCCCAGGCCCTTGATCCCGGTGGTCTTGGGCTTCGGGATGATCGGTTCGGTGCCGCGCTCGCGGCAGGCCTGACGGAACGCTGCACTGCTGTAGGCCTTGTCGGCCAGCAAGGCGCCGAAGCGTCGCCGCGGCCGGCCGGGCCGACCGGCGATCGGCGGGTAGCAGTCGAGCAGATCGAGGGCCCGTTTGATGTCAGGCACGTTCGCACCGCTGGTCAGCACGTAGATCGGAGTGCCGTTGCCGTCGCAGATCAGGTGGTGCTTCGAGCCGGGTTTGCCGCGGTTGACCGGCGACGGGCCTGTCCCGGCACCCCCTTTTTCGCGTCGATGTGACTGCCGTCCATCGCCGCTCTCGACCAGTCGATCCGATTCGCCGCGTTCAACCTGGCCAGCAGTATCTGATGCACTTGGTCGAACACGCCGGCTTCGGTCCAGCACTGCAGCCGGCGCCAGCAGGTCATCCCGGAGCCGAAGCCGAGCTCCTGCGGCAGATCCTCCCAGCCGATGCCGGTATGCAGCACAAACAGAATGCCCTGCAGACACAGCCGGTCCGGGACCGGCCGCGGCCCCGGAGCCTTCGCCGGCCACGGCGGCAGTACCGGCTCGATCAACTCCCACAACTCGTCATCGATTACCCACGCCTTGCTCACGACGACCGAACGAGACTGATCTTCACCCCGCAACGCTGACAAACATCGATTCAGCAGATCGTGTTAGGAGCTTTAAAGCGGGTGTTGTAAACGTGCGACCAACAAACCGGGCGAACCCGCCGAGAAAAGTCAAAGAGGTTCTATCGAAGGAACAGCGGACGTAGTAAGACTGCTCCGTCCCCGATCCGAAGGACGCCTGCCCGAGCATGCTGCGGTCGAACCGGCAGTCCTCGAAGGTAGAACCTTGGGCGCTGAACTGCCCGATGGATTGCCCTGAGTAGTCGGCGCCCGCCACGTGCTTGTGATTGACGATGATCTTTTCCATTACGCGTACAGAGGGTCGGTCAGATCGATGGTGATGGCATTACCCAGGTTGTTTATGAACGTCGCCCGCGAACCGTCAGCCACTATCTCGTAGAACGGATTCCCGTTCCGCAGGAAGAGCACCCAGACCAGTTGGCCCGCGGCATCCAGCCGGGCGAAGAATCCTTCCGATCCGTGAGCACCTTCACCACTGATTATGTAGCCGTCCGGGACTGCGGTACGCGCCGACTCGTCTACCTCAGCCACCGCGTCTGGGTCAACGGCGAGTCGCTCGGCCGGGTTGAACGGCTCGCCAACCTCGAACCGGCTCAAAGCCGCACCGTCAACCTCGATGGCGCGGGCAGTGCCATCCGCCCGGTATAGACCGGAAAACGCCGGCACCTCTCCCTGTTGCCACATGTCGGCAATCATGCCCGTACGCCTCACTCCCATTTCGGCCGCTCATGCAAGCCCTGCCACGGTACCCGGCAGCCATTCTCGTCCTTGTTCCGCTTGCTCGTCATACGCTTCTCGAAGCTTTTATCCCAATTCATGCCGGTGCTTTTGGCTGGGTTAGCCGCCTCGGGGTCAAGAACTTCGATCTTTACTCGGTACGTCGGGTCTTCGGCACGCACCTCGCGAGCGGCGTCCAAGCGGCGGTTGTCATAGCTGACCAACTGGCCGTCACGCTCAAGCACACGCAGCGCGGTGCCCTCCCTGTTCCAGTCCCAGGTGCCGTCCTTCATCGATTGCACGTAGTCGTTTGGCGAGACTGTCCGCTGCGAAAAGTTGATGTCGTTGGGATCAACCCAGTCGGCCAACCCCTCCGCGAGATCCTCGGCTGCCTTCTGGCCACAGCCGTCGTCGTCCCCGTTATCACCGCCGGCAATCTGCAGCCCTTCGGTGGCGGCCACTGCGCCCGCTGCGGCCGCGATGTTCGGTGCGTCGTTGCCACCCGCGCCAGCAAACACCGTCCCGGGCAGCTGCTTCGTCGCGTCAATGTTGGTGACCAGGCCGGCGCCACCGACTAGAGCGATCGCCGCTGGTGGCTTGACCACCGTGGTACCGACTGGTCCCGGTTGGGCTGCCTTGACGGCCGCCGCGTGCTGGGCTGCGTCCGCGGCGAGACGCTGTTGGCCGAGTTTCACAGCGGCGTCGGTCTCGGCTTTCAGTCTGGCGGCTGCGGCTTGCGCTGCGGCGATCCGCTGCGCGACGTAGGCGTTGTACGCGGCGGTCATTGCAGCCACGTGCGCGTTGGCGGCCGCCTGCGCGATCGCGAGCTGGTAGGTGGCCTGGGCCTGACCCTGCGCCGCTGCCGCGCTGAGGTGAGCTGCGTACGCGTTTTGCTGGTACGCGTACGAACTGGTCTGCGTGGCCATGCCGCCCCAGCTGCTGGCGCTGTTGGCGACGTTGTGGCTGTACTCGTACGATTGGTAGCCCTGGTAAGCCAGGTATCCGGTGCCGGCAACCGCGACTATCCCGAGGATGGCCCAGCCGACCGGGTTGGAGCCCAGGAATACGCCGCCGAGCGCCACGAGCGGGTTGTGCCCGTCGGCGTCGATGTTGTTTAGCGGGCTGGCGTTGCCGTAGCCGTACTGGTTGGCTTGTGCCGCCGGATCGGGCTTAAGGGTGTAGGTGTCGCGGGAGTTGAATCCGGCCGATTCGGGGTTGTACCAGCGGCTGTCGGTGTTGAGCAGTGTGGTGTCCTGGTCAGACCAGCCGCCCTGGAAGCCCAAGGGCAGTTTGTCTGCGGTCGAGGCAACTACTTCACCGGACGGGTCGTAGACGGCGGATCGGTTCAGGCTGCCGTCGGCCGGGTCGTACGAGCCGCGTATGTCGCCGTGGCGGGCATCGGCGAATAGCCCGCGGCCGGGGCTGCCGTCCAGGGTCGCTGACAGCGGTCGCGAGTCGGGATCGCGGAAGATCTGCCCTCGGGGGGTGTGCCCGGCTCCGGGTACGAGTACTGGCGAGTTGTCGATTCCGCCGTATCCAAAGGCGATGCCGTTGCGGGTGGCCACCCGTCCTTGTGCGTCGTAGGCGTAGGTGACTGTGTATCCGGGGTCGGCGGCCGTGGTCATCTGTTCGAAGGCGTCGAACGTGTAGGTGGTGGTGGCGCTGTTTTCGGTGGTGCTGCGGATGGTGCCGCGCGGTGACCAGGTGTTAGCCAAGCTGGGTTGTGTGCCGCCGGTCGCGGTGAGCAGCCGGTTGCGCTCGTCGAATGCGTAGGTGCGGGTGTCGGTGCCGGCGCTGACCGTGGTGCGGTTTGAAGCGTTGTCGTAGCCGTACGCGACGGTCGAATTGTCGGGTCGTGTCCATGAGGTTTGCCGGCTGAGGCCGTCGTAGCCGTAAGCGTTGGCGCCGTCGCCGGCGATTCCGGTGACGCTTTACCGGTCAGCAGGTCGTCTCTGTCGTAGGTGTAGGCGAGCTTGGCGGACTGGGTGCCGTTGGCTTTGGTGAGGGTGTCGCTGGCCAGCCGGCCCAGGTTGTCGTAGCCGTAGGTGCGTGACAGCGATCCGGTGCCTTGGCTGACTGTTTGCACCTCACCGGTGGGGCGATAGGTGTAGGTGAGCGTTTTTGCGATCAGCGGGTCGGTGACCGTTTTGAGCCGCCCGGCGCTGGTGTAGGTGAACGCGGCTGGGCCGGCCCCGTCGCTGCGGTTGGAAAGCCGGCCTTCGGCGTCGTAGGTGTAGGTAGCGGTGCCACCGGGCCCGGCGACGTCGGTAAGCAGGCCGCGGTCGTTCCAGCTGTAGGTGTTGTCGCCGCCGGTGGTGCTGGCCTTGCGGAGTTGTCCCAGCGCGTCGTAGTCGAAGGATCGGGTGGTGCTGGCGCCCTCGGCGCCGCTGCCGCGTTCCGTGGTGATCTGGCCGAGCCCGTCATAGTCGCGTTCGACGGACACGCCGCCGGGCAGGTTGGCACGGATCGCTTGGGCACCCTGGTCGTAGATGAAGGTCCAGGTGCGGTCCATGGCTGCCGGGTGCGCGGCGGTGGCTGGTTCCACCGCTTCGACGGGCGCGCCCCAGTCGTTGTAGCGGTATTCGGTGACATGCTGGTTGCCGTCGCTGGTACGGGTGCGGTTGCCGAGTGCGTCGTAGTCGAGCCCGACCGTGACTGCGGAGGCAGGGTCGGTGGGTGTGCGCAGCTGGGTGATGGTGCGTACGTTGCCGCCGCCGTCGTAGCCGTAGTCGGTGATCCGGCCCTCGGCGGAGGTCTTGCGCGTTACCCGGCTGTCTCGGTCGTAGCTGGTTCGGCTGGTACGCAGCGGCGCGGACAGCACGCCATTGGTGACGGTGTGTCCGGTGACCGCGATGGTGCGGCCTAGCGCGTCGTAGGTCCAGCCGGTTGCCATCGTGCCGACGATCTGCGCGATGGTGCGGCCGGACGCGTCGTAGCGGAACTCGGTGAGTACACCGTCGGCGTCGGTGGTTGTTGTCCGCTCGTCGGCGGTGTTGTAACTGGTCTTGGTCGTGTGGTTGAGCGGTGTGGTGATCGCGGTGGTCCGGCCGCGGTCGTCCGGGGTCATGGTGGTCGTGTAGTAGTAGGTGGTGCCGCCGGCCCGTTCGGTCACGGTGTCGGTGACCTGGTTGCCACGCTCGTCGTAGGTGGCCAGGCGCCGGGCGCCGAGCGGGTCGGTCGTCTCGAGGATCTCGCCGACCCGGTCGTGGGTGTAACGGGTTACGGGTTTGGTCTTGGGCCCGTCGCCGTCGGGGTCGGGTCCGGTGACGCTGGTCAGCCAGCCGTTTTGTCGTGCTCGTAGCTGGTAACCCGGCCCAGGCCGTCGGTCTCGGTCACCGCGAGCCCGCGATCGTCGTATGCGGTCTTGGTGCTCGGCGTGATCGCGGTGCTGCCGGGCGGGGTGTAGGCGGGCAGGATTTGCTCGACTTGGCGGCCCGCTCCGTCCCGCACGATTCGTGCGACTGCGCCGTTGGCGTCGCGTGACTCGGTCAGTTCGCCGAACGTGTTGCGGCCGGCCACCGAGGTCGGGGTGACGTTGTCGGTGGCGACGCCGTTGCGCCATACCGACCTGGCGGGCTCGACGATCCTTTCCTGCCGACCGGCGTTGTCGTAGGTGTAGCTGGTGACCGCGCCGGCCGGGTCGGTGACCGAGACCGGCAGGCCGCGCGGGTCACGCTTGGTCGCCGTGATCAGCGCCTGTGGGCTGTCCGTAGGATCGGTCATCGTGGTGCTGGTGGCACGGCCCATCGCGTCGTAGCCGAAACTTGCCGCCTCCGGGGGCGCGCCGGCACGCTGAAAACGCAGGTCCGAGCGCACGACACGGCCGCCCCAGCCGTTGGCTGGCTGGCTGTCACGCACCCGCAGGTAGACCGTCTTGCCGGCCCCGAGAGCCGGAGTTAGGTCGAGGGTGCGGACCGCGCGGTTGGAGCCGTCGCGAATGTCGCGCGTCTCCTCCAAGATCTTGGTCCACGTGCTGTTGTCCGAGCTGGTCTCGACGAGGAATTGGTTGTCGATATCGATGTTCACGCTGGCGCCGGTGGTGTCGGCGGGCAGGGTGAACTTGTAGGTGAAGGACGTGGTGCCGTCGGCGTAGCGGGCCTGCGACCCGTCGACCAGGGACCCGCTGTTGGACAGTACGGCGGATTCACCGGGGGTGTTGACGCCCAGTGCCAAACCGTTGCCGGAGACCACTGATTCCGGCTGGCCGTCGCCGCGCATCCGGTAGGAGATGGAGCGCATCAGCCCGGCCGGGTCGAGGACGTCCTGGATGAGGTTGTTGGCGTTGTCGTACAGGTAGTCGTGCACGACGCCGCCGGCCTCGGTGCGGCGCACCACGTTGCCGGCGCCGTCGTAGTTGTTATATTGCTGCAAAACCGTGGACGCGATCGTGCCGTCGGCGTCGCGTTTGATCTGCCTGATGCTTTCCAGGAAGCCGTTTTCCCAGTAGGTGTACGCCGTTTCGCGTCCCATCGCGTCGACCACCGAGGCGAGCTGGCCGGCAGGGTCGTATGCGCGCGACTCCACGACCATCCGGGTCGTGGCTGGGTCCATGGGGTCAACGCCGTCGCCGGTGGTGGCCGTCTCGGTCAGGTGGCCGAGGTCGTCGTACTTGTATTCCAGGATCTGCCCGCCGGGCCGCTTTTCGCGGACTTGGTTGCCGGCCTGATCCCACTCGGTGGTGACAACGGCGCCGTCCGGGGTGGTGGAGGAGGTGACCCGGCCGGCCGGGTCGTACCCGGTTTTCCAGGTGCGGGTGGCGTCGCCGCCTGTGGTGTCGCTGTTGTCGACCTGCGTGGTGTGGCCGGCGGCGTCGTAGGTGTATTTCGTGCGTGCGGTGTGGGTGATGCCGGTGATCGGGTTGACGATTGCCGGCGACGTTACGGTGTCTGGCAGCGATGCCGTGTTGTAGGTGGTCGTGGTGGTGCCGTAGTCGACCGTGGCGTCGTTCACGACGGCGCTGATTTTGGAGGTGGTCGGGCGGCCGATCGCGTCGTAGCTCACCTCGGTGGTCAGCCCGACCGGGTCGACGGTGCGTACTCGGTCGCCTGCGCGGTTGTAGTAGTAGTGGGTGATGCCGCCGGCGAAGTTCGACTCGGTGGACATCAGGCCAGGGGGTGTGGTGCCGCCGCCGATCGCGTCCTCGGTGCCGGTGGTGTAGGTGAAGTCTTTGCGTGCGGTCGGGCTGGATTGCCCGGGCAGTCTAGGTTTGACGACCGCGGTTGGCCGGCCTTTCTCGTCGCGGTAGTACCAGGTGCGGTGCTCGTAGGACATTCCGTCGCTGCGGCCGTCGGTCGACCATTGCAGCTGGTCGTTGCGGGGGTCGAGCGGATCGTTGTAGAGGTCGTAGCCGTAGTAGCGGTATCGCCAGGTGCCGTTGTACCTGTCGACGTCAATGGTCCGGTTACCCCGCTGGTCGTAATAGAAGTAGCGGGTGCGGTTGTTGGGGTTGGTGTAGTTGTTGACGAACCCGGCGGCATCGTATTCCCAGTCGCCGCTGCCGGCACTGTCGGTACGCAGGACCAGTCGGCCGTTGTGGTCGGCGTCGTAGGTATAAGTGATGGCGTCGTGGGCCGTCGATGACAAGGTGACGACGCGAACCCGGTTGCCGACTGTTGGCGGCGCCAGGGTCCACTGGGCGCCGTTGCGGTCGGTCATAGTGGTGATCCGGCCGGACGCGTGGTCGTAGGTCGCGGACGTGGCGGTGAACTGCCCCGGTTCGACCACCGTGGCCAACCGTGAGGTGGCCGCCTGCGCGCTGTAATGCGCGCTGACCTGGGCGGCTGAAAGTGGATGCCGGTAGACGGCGACCTCATCGATCTCACCGGTGAACGGGAAGTATCCGGCCCCCATCGACGGCCAGTCCTTGGTGTATCCGTTGCCCAAGTAGTGCCGGGTCATCCCGATGTGGTCGACGACCTTGCCGGAGATCTCACCGATTTTCGCGCTGTCGAGATAGAGGCTCTGCTTGTCAACGGCCATGGTGAGCACCGCGTGGTGCCACTGCCCGTCGGTAACCACACCGGGCGAAACCATCGGGCTGGAGGCTGAACCGCCGGCAGTCCACTGGTAGCCGTGCAGCTTGCCGTCGATACCGACTGTCAAGTTGGGCGCCCACCCACCGGCTGAGACGGCGGGAATCTGCATCGCCTGGGACCCGAAGAGAACCCCGGACTTGCCGGCGGCGGCCTTGAACCACAGCTCGATGCTGAACGCCACGGACGGAGCCAGCAGTGCCTCCGGCAGCGTCACATAGCTGTCAGCGGCGCCGGTGAAGCCGAGTGCCCCGTCCGGCGAGCCGGCCAATGCGCCGGGCCGGTTGGCTACAACGTTGCGGGCGGTGGCCTTGTTCTCGTCGGGGCTGCGCGCTACGACGTTCTCGAGGCTGGCTGCGGTGCTGCCGAGCGGCCAGTACGCTGCCGGGTTGTCGTCGAGCACCACTGAGCGGTAGTGCGAGGAGGAAACGTATGTGTAGCTGGTGCATGAGGTGGCCGACAGCGGGCTGCAGACCCGGGTCAGCTTGCTGCCGTCGTAGGTGTAGGTCCAGGTCGGTGCGGAAGCGCCCGCGGCGGGCGCGTCCGTGGCGACCGAGGTGAGCCTGTTACCGGTCCATGCCGGCCATAGTGAGCGGCCGCTGGCCTCCGCGAAGCCCATCCCATGAGGATCCTGTTGCCCCCTTTGGCGTGGCGCCACTCCGGTGCCAGCGGCGGTCACTCGGGCCGGCTGCCGGGCGCAGGAGCGGCTCCGGGCGGGTTGTCGGGCGGGAACGAGGCGCTGTGTAGCCCTATATGACTGCCCGGTAGCGGGCGGTCCGTGGCGGCGAGGATCGCCCGGAACAGATCCGGCCGGGCACCGTGCCCGCCATGATCGGTGAAGAAGGGAGGAGACCACGATGACCATGCGGTACGACGCTGCGCTGATGTTCGGGTACCAGATCCATCCGGTCCCCCACCTGACGTTCGAGGAAGTCGACGGGAACGGCCTGCTCGATCTGCCGTGGCTGAGCGGCACCCCGGACGGTGTCCCCGCCCCGGCCGGCGCAGCCGACTTCGTCGGCCGGTTGTACATGACGATCCCCGACGCCGACCCTACCGTGACCGACTGGCACCAGCAGGGGCATGCCGTCCGCGATCGCTACGGCGTCACCTTCGTCGAGGATGGCTGGGCACTCCGCCGCGGTTCTACCCGATCGTGTCTGCTCGCCGCGTACACGGTGCAGGGTCGGTCAGGTGCAACCCGGCCGGTGAACCTCGGCGAGCTCGTCGCAATCAGGGAACAGCACGATCTGGACGAGAAGCTCGGCGTAGTACTACGGGTGCTCGGCCTGACCCCGAAACACGAACCGCAGTGGCTGCTGGCCGTGACCAGTGCGGACCAGGTGTGACGCCGTCAATATTCGAATGCCTCTGATCTTCACCCCGTGCAGAGGACCGCGGACAGCCGTGCACAGCACCTCAGAAATCGACACCCACGACGGCAGCCAGCGTATCGCGTGGGAGGCCTAACTGTCCCCGATCATCGACGACGACATCCGGGACCGCACCGACCGCTACCAGGGCGAGGTCCTCACCGTCACCCGCCAGAGCCGACAGCGGTCGCGGCGTAACGGCGACGGCGTCACCGTCTACCTCGACGCCGAACTCCCGGCCAGCCCCAACCTAACGGAGTCACCTGCACGACCGCCCTGACCGGCGAAGTCGATCATCGCGGTGTTCGGTGGCAAAGGTATCGGCGGGAGCGGGCACTGGTCTGTATGCATCTCGGCCGAGGCAGCGTACATGGACCTGCGGAGATCATTGCATCCGACCTTGTCGATCAACGCCGCAGGTTGGTTGTCGCGACGCGTTGTCGACCACGTCCAGCGGGGCGCTGCTGCGGAGCGTGCGACACTCCCTGATCGTGGACACCGATGATGTGTGGCAACTGGTTGAACAGGCTCGACGGGAGCGGGACGGCTCACTGCAGGCAGACGAGGTTGCACAACGCATGGTCGAGTTGCTGGCAGAACGTGAGCCAGCTGAGATTGCCTCCTTCGCTCAGCCCTTGTGGGATCTGCTCGCCGAGTCGTACCGGGTCGAGCTTTGGGCGGCCGCCTACGTAGTCAACGGCGGTGCCTCTGATGACGGTTTCGACTACTTCCGCGGCTGGCTGATCACTCAGGGACGCACGGTGTTCCAGCAAGCAGTCGCCGATCCGGACACTCTCGCCGACAACCCCATCGTCATCCAATCCGCTGCAGCCGGCGAGTGTTTGGAGGATGGAGATGTCCTCAACGTTGCCTCGAACGCGTACCTGGCAGCGACCGGCCATGAGCTGCCACATGATGCCTTCACCATCCGGTACCCGGAACTCGACTTCACCTGGGACTTCGACGACGAGGCTGAGATGCGTCAACGCCTGCCGCGCCTTACCGATTTGCACTACCAGTCGGCCGAGGCATAACGACCCCACTCACAACCAACCGGCGCCGCAGGGCGTGGCCTCGTTCAGGGGGAGCGGGTCTGCTGCACCAATAGGTGACATCTGAGATGTGATTCTGACGGGTATCGGTGGCCCCACCCGGACGGGGCGGATTCAGGCGGTCGTCGCAACATTGCTGGTGAACGACTACGACGTCGAGCCTAGCGAGTACATCAGCGACGCCAGTAGCGACGCCCGCCACGGCTTGCCGGCGCGCGGATGGCGGCAAATCCGCGCATCTGAACTGTTACGCCGTGGCGGGTCCGACGAGCAGCAACGGCCTAACGTACATGCCACTTGGTAGAGCCACGACGCCATCGTTTTGCCCAGCCTGCCGGCGGGCTCCAGCTCTGTTCGTCCTCCGGCTCGGCCAGCCAACGCCTAGTCGCAAATAGACCGGCCAACGCGGCCGCGTATAGCAGTCCGGCCAGCGCCTCGCCGAGTTTGAAAGTCTCGACCCTGCCAAGTTGGATTAACAGTGCAGCCGCAACACCCAGCATCACCGGGTTCAGCGCCTCATCGGGGCCATCGGTGAACAAGGTGTAGGCGAGCTCCACCACGGCTGCCAATCCGAGGGCGAAGCCGATGCCGCCGAAAATCCCGTCACTGAGATCGTGCACTGCCGGGAACGGGCGTTCAAACAGTTTGACGACTAGCCATACGCCAATGCCGAGAACGGCGACTATCCCGATTACCATTTGGATCAGTGCTTTGAAGTAGCGTGCTCTCGGACCGGCGAAGTCGTACGGCTTTGGTGGTGGTCGACCTGGCACAGGCTCCATAGTTGCAGTGCCGCGATGCGTTGTCGAGTGCACGGTTCTCGGCAGATCAGTAAACGTGATCATGCGGCTTCGGCGAGTAACCGGGCGAACCGCAGGGCAGGGGTGTCCCAGCCGAGGGTCTTGCGCGGCCGGTTGTTGAGTTCGGCGGCTACGGCGGTCAGGTCTTCGGCGGTGTGCACGCTGAGGTCGCTGCTCTTGGGGAAGTATTGGCGGAGCAGGCCGTTGGTGTTCTCGTTCGAGCCGCGCTGCCAGGGGCTGGCCGGGTCGCAGAAGTAGACCGGTGTGCTGGTGGCGGCGGTGAACTCGGCATGCCGGCCCATCTCGACGCCCTGATCCCAGGCCAACGACTGCCTTAGCTCCGTCGGCAGGGTCGAGAACGCGGTGATGAGCTGGTCGCGAAAGTGTGCGGCGTTGCGACCTTGCGGGACATGGACGAGCATGACGTAGCGGGTGCTGCGCTCGACCAGGGTGCCGATGGCCGTCCGGTTGTGGGCGCCCATGATTAGGTCGCCTTCCCAGTGTCCAGGTATGCCGCGGTCGTCGGCGGTAATGGGACGGTCGTGGATGCTGTTCGAGCTGTCGGTGAACCGCGGAGTGCGTTGCTCGCGGCTGCGACGGCGCTTGCGATACGTGCGGCCGGTGCGCAGCAGCGGCGAGCGACTGCGTGTCAGGCCGCCTCGATCGGGCCGGTACAACGCCTGATAGATCGTTTCGTGTGTTAGCCGCAGTTCTGGCCGGTCGGGATGTTGCAGCGGCAGGGCACGGCAGATTTGCTCCGGGCTCCACCGTTGATTTAGCAACTCTTGGACCAGGTCGCGCAGCTCGGTGTTGGTTTGTAGCTTCGCTGGTTTGGGTCGTGGGCGACGTGCCGCCGCCTGCTGGTGGGCGGCGAAGGGGTGGTAGTCGCCGGTTGCCGGGTCGCTGTTACGGCTGATCTCTCGGCTGATGGTGGACGGCGCTCGGTCCAGCAGTGCGGCGATCGCCCGAATCGAGCTGCCGGCTCGGTGCTCGTCAGCGATGGTGATGCGCTCGGACTCGGACAGGTAGCGGGCCGAAACAGCCCGCTTCGGCACAGCGATCGGCGCATAGACCCTGGACTCGCCGTCCGCGCTGATGATGGTCCGGCCGTATCGCCAGCGGGTGCCGGTGCGACGGTTGATCCCGACTTCCCTGCAGGCCGCCGAGTTGTTCATGCCCTGCGCCATGAGGCGAAGGTAGTGATCACGTTTCGCTTGCTCCGGGCCGGCACCGGGTGGCTTGCGCGGACAACGAGGCTTGGACACGGCAACTCCTGAACGGGTCAGGTGTTGCGACGACCGTTAGAACCTAAGCCGGTCCGGGTGGGGCCACCGCAGGCCGCCAGAATCATCTGAGATGGCTTGCCGTGACGGCGGGCTGGAAGGATGTTGCTGTGCCCAAGCCCTACCCCCGGGAGTTTCGCGATGACGTCGTGCGGATCACCCAAGGCCGTGACCCGGGCGTGACGGTCGAGCGAATCGCCAAGAACTTCGGGGTCCACCCGATGACGTTGTTCAAGTGGCTGCGCCAAGCCGAACTCGACGCCGGCGCCGAGCCCGGCGTGAGTCGCAATGATTCCGCCGAGCTGCGCGAGGCCCGCAAGCGGATCAAGCTCCTCGAGCAGGAGAACGAGGTCCTGCGCCGGGCCGCGGCCAGTCAGGCCGCGTGACTTGACCTGTCACCTATCGGTGCAGCAGAACCCTGTGTCACCAGCCGCGACCTGAGCCGAGCATCCATGCTTGCTGGGTTGAGAGCGCCGGAACTCGTTGTGCTGCAGTGGCCTGTGGCTTATCGAGGCTGGTGGGTGTCGGCGTCCTCGATGGCGCGGTGCCGGTTCTGTACCCGCCTGTCGATGGCTCGACGTAGCAGTGGCCAGATCAGTCCGAGGAAGAGCACATCGACTAAGAGCATCATCGTGATCTCGGCGGCAAAGTGCGCAGGATCAGTCATGATCTCCGTGTAGTGATGAAGGAAATGGATCATGCGGCTTCCTCCCGCGAGTGAATCAGCCTTGCTGGCCAACCAGCCCCAACGTATATGAAAACGGTTTTCATAAACAACTGCGTATATGAGGACAGGAACGCCCCATCGGATGGTCATTTGCTGTGGTCGCCGGGGACGTAGGTCTTCCAGGTGCCACCTGTTTTGGTCCAGACCTTGGCGACGTGTTTGTTGTGGTAGCCGAGGGCGTCGGCGATGACTGGTGCCGGGCTTGCAGGACGAGTTGGCGTAATGCGGCCACGCGGGTGGCTTTGGCGGGGATGCCGGGCTGGTGGATGAGTAGCAGCAGGGTTCTCGGATGCAGTGGCTGGCCGGCCCTGTAGCCGGGGAACAGCCAGCGGTTGCCGGGGTTGGCGGCGCTCGTCGGGTCCGGTTGGCCGTCGACGAGCTGGAGCAGGATGCCGGCGAGTGCCTCAGGGACTGGTGAGGGCGGTGTGCCCAGGCGGATGAGGACTTGATCGCCGTCGCGAAGGATGTCGTCGCTGGTGAGACGGACGATGCGGCTGGCGGGCTGGGCGTAGAGCAGCATCAGGCAGGAGATGTTCGGACTAGCCGAGAACTTGGCCTGACGCGATCGTCAGGCTGTCGGCCGGCGCCGTAAGCGAGTTAGGCGCCGGCTCATGACCAGGACGAATGCCCAGAGGATGTGCGCGGCGGAGTAGTCGGCGCGGGCACCGCGGACGGCTTGCAGCCGATGAGGTCCAGTTCCCCCAGCTGGACTAGCCGGATGGCCTCGGCGCGGCAGGTGGCCAGCGTGATGCCGTTGCTGCGGGTGCGCCAGGCTGCGACGCTCGTGGTGGTCGAGGCTCGGCGGGCGCCAACACCGAGATGGCCCTGCGCAGCAGCGCGGTCAGCGCGTTGACCGCGCGGGTGCGTTCGCCACTCATCTGCTCGCGAGCCGCTGTCAGGACCCGGAGCGCGGAGCAATCACCTGCCTGCCGCGGCCAGCACAGGCGGTCAGCCTCCAGGCCGCAAGCGGCTTGGGCCGTAGCGACGGCGCTTTTCACTCCGATCGCGGTTGCAGTACACCAGTGCCCAGCACCGGCGTCGACGCCCACCGAATTCGGTTCCACCTGATCGAGATATTGGCGCAGCGCCTGCCGAAAGTCCTGCTCGCAGGCTACGCCGGACCCCACGTAGGGCCGGTGCGTGACTGGTGGCCGGTGGCGCGGCTGCTGTCGTGGCCGCCGCCTGCTCACGGTCGGTTCCCTCGCCGGGATCCGGCTGCGGTCTGGGCGCTCGATCGGCGATCACCGGCCGGTGTCGGCAGGTCGCGGTGCGGGTCACACTCTGGCGTGGCGATGACCTGCCCGCACCGCGGTCCCGGTCACGAGTGATGCTGTCGGAGTACGGCCGATGCGACGGGCGGGCATGGTTTGACCTCCATCGCTGAACACGTTCATGGGGTGCCGCGGTTTGGTCACAGGCGGCGAGGCGGGTGCCGGGTGCACACGCGCGGGTGCGTACGCACCCGGCCCGGGTGAAGGCACTGCTGGGTACTGCGACCATCACCCGGTCTTGCCTGACGCCGTTGGCAGGCAAAACCTTGGACGGTCGCCGGCGTGGCCCGGCGGCCGCAGGTGTGGAATCCGCGTGCTTCAGGTGAAAGCCTGACCCTCGTCGAAGTCACCGGCCCGGACGGCGGCGAGGAAGCCGGCGAAATCCGCGCGGCTTACCTGCAGTGCGTCGGCGTCGGGGTTCTTCGAGTCGCGGATCAAGATTTGGTCGTCGACGGCGGCGACTTCGACGCAGGTGCTGGTCGCGCAGCGGCTGCTGCGTTGCCACGCCGGGCCGCCGCTCACCAGTGCGTTGTCCATGTCGATCCTTTCGGTGGGCACGGCTGGGTAGTCCCGCCGGTGCCGAGTCGGGCGATGCGGTGGGTGAGGTAATCGGGGTCCGGCATGCCCGGGTCAGGGCTCAGGATGGCGCCGGGCAGGACGGGAAGAAGACGCGGTGAGGTCGGATGGCGTAGCGTCTCCGTTGGTGTCGCGGTGACCGCTCGGTGCAGCATCAGAGTCAGCCAAGGGCTAATTCGCCGGTGGTAGCTGTCGCGGATGCGGGCGAGTTCATTCCACGCTTCGCCGCGGTGCTCGGCGATCACGGTGAGCGCGTTCGCCACGGCGAGCCGGTTCGGATCGCCGTTGTGCTCGGCGGCCTGACGACGGTAGCGGCGGCACGCTTCGGCGGCGTCGGGCAGGCCCAGGCAGACGGTGATGTCCGCGATGACGCCGGCGATGATGACAGCGCGACCCCGGTTGGCCGGCCGGCTGCTGCTGGCGGCATCGGCGTCAACCGCTTGGTGTAGCGCCTCGGCGTGATCGTGCTGGCGGTTGAGTGTCTCCGCGAGCAGAATAGCTTCGCCTCGGCATCAAAAACTTGCGACTCCTCGCGGAAGCCCGATGGCGCCATCCCAGCAACACCTGCCGCTTCGAGGCCGAGTACCTGTCCATCACCGAGGACCCCGCCGACAACAATCCCGAGCGGTACTTCGTCGAGCTGTCAGCACCCCACCCCGACAAAAGCCACAGCAGCCTCTGGACTCTGGAACTACAGCAGTGGATCCCGGACTACGACGACTCCGAGGACGACGGATCCGCCACCAGCGAAAACATCCTCGACTGCCATCTCGACACTCCACCAGCCGTCGACCAGATCGTCGCCCTGCTCAACCTCTGCACCGACCACCCCAGCTTGCTGACCACCTGGGCCAAAACCCCCATCGGCAATTCGCTCGCCGGCACCCCGTACGTCGTCGACGAACGCCACGACGACTAACCACCACCGCAAGACCGCGGGGCGGGCGTGAACGCCCGTCCCCCGCAAACACCGCCAGCCGGCACCGAACCGGTCAGGCCGCCTCGTCCCAGTCCTGCAACGCCGAGTCCATCAACTCAGCCGCCTTACGCTCGCTCTCCGGCAACACATGCGTGTACACCTCCCGCGTGGTCCGCCCATCCGCATGACCGAGCCGCTTCTGCATCACATGCTCCGGGACACCAGCGTCCGCACCCGCCGTCGCGGACGTGTGCCGGGCGTCGTGCAGCACGATCTGCCTCACCCCCGCCTCCAGGCAAGCTTTCTCCCACATGTCGGTGAAGTACCGCGGGTAGTACGGCTCCCCATCCTCACGCGGGAACACGTAGTCCCGGTCGTGATACAACAGCCCGGCCTCCGCTTTCTCAGCGTCCTGCCGGACCTTGTGCTCACGCAGCACCCTCACCATCGCCGGGCCGATCGCTACCGGCCGGCGACTCTTGCCCTTCGGCGATTTCTCGATCACCTTGTTCCCGCAAATCGTCCGCTGGATATGCACGTACACGATCCCCTGATCTAGATCGATCTTCGCCCAGCGCAGCCCCGCCAGCTCCCCACGGCGCATACCCGCGACGATCGCCAACGCCCACGCCGCATACAGTCGAGCATCGCGGTGATGCCGCAGGAACGTCTTCGACTGCTGCGGCGACCACACCCCCTTACGGCCGTGATCCTCACGTTCGGCCGGCCGCGGCTGCCGCACGTTCTCCAGATTGATCCCCAAATCCTTGAACGCCTGCTGCAACACCCGGTGCGTGGTGCGCACCGTCGTCGGCGACAACGGCTTCTTGTCCTTGCCGCCCTCCCGCAACAGCGTCTTGTACATGTCCTGCACGACCCGCTTGTCGAGGCTGTAGAGCTGCCGGCCCCCGATGTGCGGGACCACGTACATCCGAATGATGTTCTTGTAGCTGTCCAGCGTGGTCTCTTCGATATCGAGTTCACGCTCCGACAACCAGCCGTCCAGCTCCGCCGCGACGCTTCCATCAGCGGCGATGCTCGCGTCCCCGTACGCTTTCCGCGCTTCGGTTTCCGCTTTCTTCGCACTGCCCTTGGTCGGGAATCCGCGGCGCTTGTGCTGGCGTCGTTTTCCGTCGTCTCCCATCGGGAGGTCGATGACGAAGTACCAGTTGGTCTTGCCGTTGGAGAGTTCGTACGAGCCGACAGTCAT

Protein sequences of DBSCAN-SWA_3

>NZ_LT827010|6859610:6922095|6906420_6906831_-|WP_014693227.1|DBSCAN-SWA
MIADMWQQGEVPAFSGLYRADGTARAIEVDGAALSRFEVGEPFNPAERLAVDPDAVAEVDESARTAVPDGYIISGEGAHGSEGFFARLDAAGQLVWVLFLRNGNPFYEIVADGSRATFINNLGNAITIDLTDPLYA
>NZ_LT827010|6859610:6922095|6864876_6865161_-|WP_014693185.1|DBSCAN-SWA
MATAGTLTAQSVVQRASGARFRKFRGKLFVANASLAFELDEIAEFIFRQVDGESSVEAIGAKVAAEYDVDVAEAVADSLELLSQLAQNDMVHSV
>NZ_LT827010|6859610:6922095|6861863_6862541_-|WP_014693182.1|DBSCAN-SWA
MLDALNRLTVDWSDLPKARQQTKEILTALAEDKNALEELLARAREEEDLFDKCEHHRLLDKLVIYDALDRGFRIRVHVSTEDHRDRPHDHRFSFTSLILRGNYRHVRHELVGNLGDVPNDVQDDFDARESDLRVVPRFVTTERAGNCYTLHHSEIHTTYTTPKTVSLFLRGPAEKERSLITERETGRVWWRFGEDQEKASRRGSKRISKQYFDDLTGRLRAMEVL
>NZ_LT827010|6859610:6922095|6917897_6918092_-|WP_014693233.1|DBSCAN-SWA
MIHFLHHYTEIMTDPAHFAAEITMMLLVDVLFLGLIWPLLRRAIDRRVQNRHRAIEDADTHQPR
>NZ_LT827010|6859610:6922095|6860428_6861169_-|WP_014693180.1|DBSCAN-SWA
MSITQKVLRYGDSSWQRIDIYEPGDSAPRCRAVLIHGGFWRHDRTALDLEPLACALVARGCGVAVLEYRPVWDGGAFPASVQDCVAAMAALEGSDERWRDAVVTGHSAGGHLALSALAGRAGKRRVVLLAPVTDLESAAELEVGDGAIGHFLAKHHAVGGRTVEAVPVIGSADVTELVVVQAENDQAVPSALMDRQVARWRHDGLPVTHHLVAGARHMHLVNPQRGGSDVTMALLTGAELSTGNPR
>NZ_LT827010|6859610:6922095|6866724_6868926_-|WP_014693188.1|DBSCAN-SWA
MCGLAGCAALGGASLGGDAEALLQRMTAAVSHRGPDGRAFHRSESVNLGFTRLSLVDPVGGGQPLSTDDGSLVLIANGEVYNHRELIAGLPTGTKMRTGSDCEVLLHLYRRDGLNFLDAVRGMFAVVLWDRNRNRLIFARDRFGIKPLYYHRNQERIIFASEIKALFEDPSCPREIDWLGALSDQMMTGAMVLDDSQPRSWFKEIELAPAASIVTIDLLTGDTKTHQYWSFPTFDGARTGSEAELIDRYRDALASSVAECGVADVEVGLFLSGGIDSAAVAAFAPEKPRTFTALNGSTLLNGDAEYGDRIARHVGLVNHQVLFDTTVTPSADEWKRLLWLLETPLAGPEAFYKYELYRYVGAYAPEIKAMLLGGGADEFNGGYSVSFAGGGDWTDFESNVRRMELRTAQWTRPDLGTWWEQSDRSLVRESVLRDAAGGTGRDAYDMLFRWKYRDVQQYNCWHEDRTAAGNGIEARVPFLDHRLVELVAAVPKQLRPALVWDKQILRRAMAGLLPQDVVNRPKVPFFYGDGVLHTYRTFVRMLAQNGGVLLDEALSGAGARQFLDADNIRTALHGLQQDPASGHVEFLLHAVNLGLLEQMTHSLPARPAEAVTAAVPESITVHDWDEQRSSIEEAVLQRPAIDDETVVGLADGALLLHSPDDPATWYVVVDGAIEYVIDEDDNPHWPALLRALGEETPLGVVRETLGITLAVARDLVVEGLESGVLTLSAEVVG
>NZ_LT827010|6859610:6922095|6900537_6900813_-|WP_155123685.1|DBSCAN-SWA
MSVLVGFAIGSSAWTVCCAHTEPSCFRKGAVSDSRQREIRFRIQGISPSRWIIGASTVTPQHAGCGELADLVAGCFRFRQRILSAARENWI
>NZ_LT827010|6859610:6922095|6906842_6908567_-|WP_043512519.1|DBSCAN-SWA
MANTWSPRGTIRSTTENSATTTYTFDAFEQMTTAADPGYTVTYAYDAQGRVATRNGIAFGYGGIDNSPVLVPGAGHTPRGQIFRDPDSRPLSATLDGSPGRGLFADARHGDIRGSYDPADGSLNRSAVYDPSGEVVASTADKLPLGFQGGWSDQDTTLLNTDSRWYNPESAGFNSRDTYTLKPDPAAQANQYGYGNASPLNNIDADGHNPLVALGGVFLGSNPVGWAILGIVAVAGTGYLAYQGYQSYEYSHNVANSASSWGGMATQTSSYAYQQNAYAAHLSAAAAQGQAQATYQLAIAQAAANAHVAAMTAAYNAYVAQRIAAAQAAAARLKAETDAAVKLGQQRLAADAAQHAAAVKAAQPGPVGTTVVKPPAAIALVGGAGLVTNIDATKQLPGTVFAGAGGNDAPNIAAAAGAVAATEGLQIAGGDNGDDDGCGQKAAEDLAEGLADWVDPNDINFSQRTVSPNDYVQSMKDGTWDWNREGTALRVLERDGQLVSYDNRRLDAAREVRAEDPTYRVKIEVLDPEAANPAKSTGMNWDKSFEKRMTSKRNKDENGCRVPWQGLHERPKWE
>NZ_LT827010|6859610:6922095|6919708_6919927_-|WP_014693234.1|DBSCAN-SWA
MDNALVSGGPAWQRSSRCATSTCVEVAAVDDQILIRDSKNPDADALQVSRADFAGFLAAVRAGDFDEGQAFT
>NZ_LT827010|6859610:6922095|6894614_6895118_-|WP_155123683.1|DBSCAN-SWA
MLTVGSAAALSAACGQAGGPVATLAGAPHGIVVNRGGVVEVLDDTTTGTVRQVTEQDTGGTSADPLAMTKVRQLAAHTIAGLRAGRLVALDPAHADRPRTVAPASDWFPDTALTGGWAVTESLNQPPCPAIDGTAAGTTRYRLERHDLSTGKTLRTTCRPCGPDPGF
>NZ_LT827010|6859610:6922095|6897992_6898298_+|WP_014693214.1|DBSCAN-SWA
MSIWQSSLEGGSGCLDLGRGLFGGGDTSIGPGQQHNGGWGGADDCGDDADGDHGWVGHGGHPGQGSFDDCDPGRGSSDDCDPGRGGNGSMGHDHHMIPFCH
>NZ_LT827010|6859610:6922095|6910125_6913503_-|WP_043512523.1|DBSCAN-SWA
MGFAEASGRSLWPAWTGNRLTSVATDAPAAGASAPTWTYTYDGSKLTRVCSPLSATSCTSYTYVSSSHYRSVVLDDNPAAYWPLGSTAASLENVVARSPDENKATARNVVANRPGALAGSPDGALGFTGAADSYVTLPEALLAPSVAFSIELWFKAAAGKSGVLFGSQAMQIPAVSAGGWAPNLTVGIDGKLHGYQWTAGGSASSPMVSPGVVTDGQWHHAVLTMAVDKQSLYLDSAKIGEISGKVVDHIGMTRHYLGNGYTKDWPSMGAGYFPFTGEIDEVAVYRHPLSAAQVSAHYSAQAATSRLATVVEPGQFTATSATYDHASGRITTMTDRNGAQWTLAPPTVGNRVRVVTLSSTAHDAITYTYDADHNGRLVLRTDSAGSGDWEYDAAGFVNNYTNPNNRTRYFYYDQRGNRTIDVDRYNGTWRYRYYGYDLYNDPLDPRNDQLQWSTDGRSDGMSYEHRTWYYRDEKGRPTAVVKPRLPGQSSPTARKDFTYTTGTEDAIGGGTTPPGLMSTESNFAGGITHYYYNRAGDRVRTVDPVGLTTEVSYDAIGRPTTSKISAVVNDATVDYGTTTTTYNTASLPDTVTSPAIVNPITGITHTARTKYTYDAAGHTTQVDNSDTTGGDATRTWKTGYDPAGRVTSSTTPDGAVVTTEWDQAGNQVREKRPGGQILEYKYDDLGHLTETATTGDGVDPMDPATTRMVVESRAYDPAGQLASVVDAMGRETAYTYWENGFLESIRQIKRDADGTIASTVLQQYNNYDGAGNVVRRTEAGGVVHDYLYDNANNLIQDVLDPAGLMRSISYRMRGDGQPESVVSGNGLALGVNTPGESAVLSNSGSLVDGSQARYADGTTSFTYKFTLPADTTGASVNIDIDNQFLVETSSDNSTWTKILEETRDIRDGSNRAVRTLDLTPALGAGKTVYLRVRDSQPANGWGGRVVRSDLRFQRAGAPPEAASFGYDAMGRATSTTMTDPTDSPQALITATKRDPRGLPVSVTDPAGAVTSYTYDNAGRQERIVEPARSVWRNGVATDNVTPTSVAGRNTFGELTESRDANGAVARIVRDGAGRQVEQILPAYTPPGSTAITPSTKTAYDDRGLAVTETDGLGRVTSYEHDKTAG
>NZ_LT827010|6859610:6922095|6871751_6872981_+|WP_014693190.1|DBSCAN-SWA
MLLFVESAPTGAGMSHVRWAVDHGFDAAYVSANPEWAPERLGGEVMETLESRGRVFKVPSSEVTEVPAWLVSSIEQAAGPSGVVCGLDRSLPFAAALAEAVGAPYPSVPAMQTFRDKRAARRLYDKLGITSARWAAPADADEFVAFTEEIGGPVVLKNCRGTGSMDVRLVESSTEARERYLELSNAERYLDGDLMAEEYLTGPLYSLETIVSDGTCHHLGVTDRQIGPNPGFCEVSYTFPVQVPWQYENEMRRAVEACVQAYGIRQGMLHTEFIVTSHGAAIVELNVRHPGGLLTMMMSDCLNSSVSEILSLSALQMPLPDLSHNGKASTTVTVYPQVAGRLVQMRGLDEVGAAPFVVQALPSAAPGDWVQPPTDYRGALCQIRTVAESSNLSFNAAMAAARGISAVVE
>NZ_LT827010|6859610:6922095|6893840_6894365_+|WP_014693208.1|DBSCAN-SWA
MTARPLTGEPLALDLVNTEWVDHGRTVDLFDEPGGLLAWLHEQHLTGNHTTVAAPLRQARSALRQALEQPDEHAEQQLNAILARGVVRYTLHQGAVREGSDVDADWSAAWHAVRNYLDLIRQDPTRIRRCAHPACVLYFFDISRNGTRRWCSMDGCGSRAKAARHYQRHRTTPG
>NZ_LT827010|6859610:6922095|6892440_6892923_-|WP_014693206.1|DBSCAN-SWA
MTRDPSSTPQPPRHPLPPFTVDTARAKVQAAEDAWNTRDPRRVAAAYTPDSMWRNRDTFLTGRAEIEAFLTHKWRRELDYALRKQLWAFHDNRIAVRFQYEWHDPSGQWWRSYGNEQWEFDEHGYMSRREASINDVAINPDQRRIHGPRPAHDTTDIPLR
>NZ_LT827010|6859610:6922095|6881670_6882111_+|WP_052311961.1|DBSCAN-SWA
MRQVAFSVSVVTVAGHSPRAFTATSFTSVEIDPPLISVCVSQDGSAWPTLRDASHIAVNVLSEDQEDVARLFATPGIDRLAIHGDWRPGEQGCPLLGSVLAHLECKVAHYVEAGRHAIVLATPTSLAWREGRPLMRHGGTYTALAY
>NZ_LT827010|6859610:6922095|6920148_6920415_+|WP_043512524.1|DBSCAN-SWA
MVAVADAGEFIPRFAAVLGDHGERVRHGEPVRIAVVLGGLTTVAAARFGGVGQAQADGDVRDDAGDDDSATPVGRPAAAGGIGVNRLV
>NZ_LT827010|6859610:6922095|6900134_6900509_+|WP_080128091.1|transposase|DBSCAN-SWA
MTSWLLTHPDRLAEDDREQLARARGACPHLDALATHVSAFAEILTARDGQRLNDWIAAVVADDQPDLRSFTAGLRRDHDAVVNGLTMTYSSGVVEGHVNRIKMIKRQMYGRANLDLLRKRILLA
>NZ_LT827010|6859610:6922095|6888987_6890082_+|WP_014693204.1|DBSCAN-SWA
MTGDGRHENAALVRENGGLTLRFAGSCNPEAIQILRAGVCGTDLQILRNARPDAARILGHEGLGILPDERRYVLFNPVDPDDQDRILGHSYDGIHQRYLDAPGRPPLVSAAPNLPADLAVLVEPLAAVLYGWELAAPRSSVGIWGAGTTGVLVALVAEIRGVRAHLIHRRTDRLAFLRSTVQLLSTQTSTKLDQRRAARLDGAFICLPREGAHGALADALDAVGDNATIDLLGGFGTNDRHPDLPGVDLGQIRRSNVCGSPVLGAVTPARTRGGKQVSLTGHRGTSAAHMAEAQDLLIEHAERFGALITHVLALDVAGLEVERMARGGTRPSGRAEYIKVAIDPTMPDGSRRRPDWTTTIEDLK
>NZ_LT827010|6859610:6922095|6885896_6886883_+|WP_014693201.1|DBSCAN-SWA
MSPGRLDSRRFFDAAYTRRFLREELTTVDGKADAYAVEARFRQTLYACAQATHADDSGLGMQIRQVGLGMFRPDAIAAGKAVPTLEYLRRFDCHPYAYFPVQITAKEYEEIWRYQLNVASGERLALLDLMFSWSQSILVQFRRTAAVIDVPVTVLMADVKGPADPVNREGWELRAHLASPSRVETYFHTADEPADVVRDGGLLLGARRFAEMLAEPCDEARDVAGAIARLASTIATDARAAEATSDATVSPGIVDPDPLVEIDLAKSRRVDTWQIIRHFGAACEMYSGPGRPTIWQAGSDGWWNRVGLLADRDKWLTATALGDGTDQR
>NZ_LT827010|6859610:6922095|6865160_6865943_-|WP_014693186.1|DBSCAN-SWA
MIIDREHILAEMKVRALVPDDCLAVFAVGSIARGWANPGSDFDFIAITARPWSVQGARSVPVPLEPNAVQALELQVGERRWEIAYWLDGQIDQMLAKASWQQFDAGISSLKVLTDPEELLLGRFPTAVPLLGADWLERRRAQLAESAYKAFMTTRSLAEADGNVEDVFGMLAAGDAHSAVLAARKAFGHIVDALLESNNDFASRSPKWRARRMRDAGLPVLPFERYWAVETMADFDEQDPAAWAARVAHLCKDLSVEIEI
>NZ_LT827010|6859610:6922095|6877903_6878170_-|WP_014693195.1|DBSCAN-SWA
MTPDLDPSFVRLLQRSLGGAAEAEPLHPDADLRALGLDSMGIIGLLVDLEEEFGVSFPDHALTFATFATPRTLWSALAELRSPVDGLA
>NZ_LT827010|6859610:6922095|6884290_6885925_+|WP_043512502.1|DBSCAN-SWA
MLLDATVRPAGGAAPLWTPDRLWSQGPSVFLHDQATDGVHEAHLAHGDEPVLRFGHWHSQEAWWALQLGRTRAAHLQRHLAGLPNGARTRVSAVAAWTENLSLVALNDYDEVDPPSLVLFIGDRISHVVTLDREYAAHVGDACFASPERIVVTDDYLHLVQCLDLSGRILWRRGERGKPGADIAALFTPIACCALDGTIVIANRRSSDLITLDLDGNVIQASIPGAHVRSASAMTALDDKHALISDAYAGSLHLLTANRDRWTLENVAHPEPTPATGEFSFPRAILSVDERLLIADTNNSRLLCFPGDPPLALPVPGWPRSAIVVDDAVLVADGLGSVLRKHPRHLSADTPGIPLEVRDRQGRPVALADPHHLAHHDANSFWLTDSSLNDVLLITLDGTVSWRWTESPLADLAPLSDPHQTLPLTGTDEILVVDSLNHRVLQAAPSTGAFRAVLGDDAEEAIEYPRFLLPIPDGWLLSSESPGCLSTFDSKWRHRAQLAVHPADSPRPVHMAEPPRALFATADFLYVPDFMRGVVYVARQTGQP
>NZ_LT827010|6859610:6922095|6901998_6902145_+|WP_014693220.1|DBSCAN-SWA
MQLTEVLDVLKRLIEAAEHPDITEVSVFSRGPELPRNGIAVKDRWSGA
>NZ_LT827010|6859610:6922095|6915590_6916154_-|WP_155123686.1|DBSCAN-SWA
MITFTDLPRTVHSTTHRGTATMEPVPGRPPPKPYDFAGPRARYFKALIQMVIGIVAVLGIGVWLVVKLFERPFPAVHDLSDGIFGGIGFALGLAAVVELAYTLFTDGPDEALNPVMLGVAAALLIQLGRVETFKLGEALAGLLYAAALAGLFATRRWLAEPEDEQSWSPPAGWAKRWRRGSTKWHVR
>NZ_LT827010|6859610:6922095|6920486_6920885_+|WP_014693235.1|DBSCAN-SWA
MRLLAEARWRHPSNTCRFEAEYLSITEDPADNNPERYFVELSAPHPDKSHSSLWTLELQQWIPDYDDSEDDGSATSENILDCHLDTPPAVDQIVALLNLCTDHPSLLTTWAKTPIGNSLAGTPYVVDERHDD
>NZ_LT827010|6859610:6922095|6901110_6901578_+|WP_043515861.1|DBSCAN-SWA
MTTSASSVITAINTRRPGLKPAKQHMLMFFMQGHHLAWRDRALFDEPMHATERAVEIDASADSAEPQITDEAALNTIGYVIARYSALSPADLRTLIQASQPWQTATKPGSESRIEWALLRDWFQRPDETDDPDDERPNRAEVAAAEAYLASRARK
>NZ_LT827010|6859610:6922095|6872992_6874183_-|WP_155123682.1|DBSCAN-SWA
MPAGSPDGLNLVRSWDVPPGQTVTSVLNALDLLEARHESLRTIFPDTPSLAVRQVILAPRGVSVEVLEVTDAADADRHAQELRRRTFSLDSEKPLRGMVFTIGGVPVRAALCWHHIAVDGWAIQRLHREFADILAGRTLTDPAVSCRELAWEEQSDPAVERTARAVEYWTRTVGDVPSGRAASLGTLRTRWATLRSSTMREAARLLAAECGASLHSVVLAAYCHAIAERDDTDSPLVALISGNRAGTRMKQVVGTVEQVSPVRVQVDPAESFSALVRRVHWDTITAYRHGRHNVDVVSREVGSLGYEGSGFGFTYFYNYMPRPARSTVAAPAHPPTRITTRDAGRDNGYPVYLVVDDDTELTCDLRDAPPTPGYEPLERLLSCIQQVVAAEADGGS
>NZ_LT827010|6859610:6922095|6904160_6904757_+|WP_043512516.1|DBSCAN-SWA
MTRSAVRGILATLMVLLGAVATLMTSPTAASASPIGATELGAVDLGGYCRSQGNVDAVLSGGTAYDWHCRTRDGQNTDLSFTKACQWTYPGELPGSAAFVFDRIDNFYAPASVQCWKASTDEVTAPALDGYCSHHPTGDRAVLTGNTVYDWKCESQSPNGPVYSPVNVLQACQQTKMRNSAVDRFTNFYDPYSWQCRV
>NZ_LT827010|6859610:6922095|6870076_6871336_-|WP_080128087.1|DBSCAN-SWA
MSSNGRFGALVERPFRLLWSGRTASAVGDSLMPVTVTFTVLSVGGSASDIGLVLATTMVARMVLLIFGGVLADRLPRRLLLMGSDVFLFCVQTVVGILLLQGHKSVGMLLVAALCYGAASAISKPALIGIVPQTVSNARLQQANALMELSKSGAEILGPAVAGATVALASPGWVYLLDAATFLVSAVTVIGLQLAPMADREPESFLKNIVGGWREMAARTWYWGAVCCHGVWNVGSCAFYVLGPAIVATQTGGAASWGLVSASMAGGAVVGSAVALRVQPRRPLVAAHVALLLVVLQLSALIGPSPTGVIMAAGFVSAAGIAYANNLWTTSVQRLIPEKVLSRVNSYDWLVSFAVAPLGYGAVGPLSEKIGNAATLEIALVIVIAAATAIMLVPGIRALQQTRSGALEGWPELAARGDA
>NZ_LT827010|6859610:6922095|6913741_6914233_+|WP_014693228.1|DBSCAN-SWA
MTMRYDAALMFGYQIHPVPHLTFEEVDGNGLLDLPWLSGTPDGVPAPAGAADFVGRLYMTIPDADPTVTDWHQQGHAVRDRYGVTFVEDGWALRRGSTRSCLLAAYTVQGRSGATRPVNLGELVAIREQHDLDEKLGVVLRVLGLTPKHEPQWLLAVTSADQV
>NZ_LT827010|6859610:6922095|6905290_6906096_-|WP_085945605.1|transposase|DBSCAN-SWA
MSKAWVIDDELWELIEPVLPPWPAKAPGPRPVPDRLCLQGILFVLHTGIGWEDLPQELGFGSGMTCWRRLQCWTEAGVFDQVHQILLARLNAANRIDWSRAAMDGSHIDAKKGGAGTGPSPVNRGKPGSKHHLICDGNGTPIYVLTSGANVPDIKRALDLLDCYPPIAGRPGRPRRRFGALLADKAYSSAAFRQACRERGTEPIIPKPKTTGIKGLGKLRYVVEQTFALLHQFRRLAVRWERRLDIHDGLVSLACVLICWRRVINWTR
>NZ_LT827010|6859610:6922095|6859610_6860432_-|WP_014693179.1|tRNA|DBSCAN-SWA
MTDAVTVRTVGLDQATTPLRIGVLVSATGANLRTLLDMAAADPDTYEVALVASHAPGVPAIDVARSAGVPAWPGDFDDYCGLSSQASTDADRARYRTRAREWHDRLNARIGAWEAVHGRLDLIVLAYHRWIEGDLLQRFAGRMINQHPGDLSLLGSAGERLLIGKDPVRLAMKLGHRSTRTSCFLVDGTRDGGAVLCLGPSVPVEDRRPTAAEAHEQEMRQKAASDQVALRWTVRAIAEKRLAIDTAATHRDGSPVVLIDGTPTPLGGRRFGL
>NZ_LT827010|6859610:6922095|6914748_6915291_+|WP_043515865.1|DBSCAN-SWA
MDTDDVWQLVEQARRERDGSLQADEVAQRMVELLAEREPAEIASFAQPLWDLLAESYRVELWAAAYVVNGGASDDGFDYFRGWLITQGRTVFQQAVADPDTLADNPIVIQSAAAGECLEDGDVLNVASNAYLAATGHELPHDAFTIRYPELDFTWDFDDEAEMRQRLPRLTDLHYQSAEA
>NZ_LT827010|6859610:6922095|6863796_6864816_-|WP_014693184.1|DBSCAN-SWA
MCGTVGLFIGCAALSYCPKELLLQTAQQAVGNEPEYRSPFRNWHERASVRQAPRRLLTEGAIRPYFPAELVPVTRHPLIKGLAPETFDEVLIQHLYRYLNFTARLEYSVVNRTVLGIASGSVGVTLPEEMRFDAYKMYCDEAYHTLFSVDLARQVQQRSGVVARLPDEPYFIVRLKQLIAELPERDRALAELLFVIVSETLISATLADVPEWDGVSAAVRGTVRDHAADEGRHHAYFAAFLRFLWGQLSSDDRRRAAVLVPRLIDIFLRPDVPALRAEMVGYGLTAEEAECVVDETYTPDVVREHVAATSRQTVRYFESLGAFDDPLAADELHRYGMAS
>NZ_LT827010|6859610:6922095|6878159_6879401_-|WP_014693196.1|DBSCAN-SWA
MNRREFVERFGSPLYVYDLDRVDAALVDLRASVPEQATLFFSQKANPHPAVVERLIAAGCRAEVSSSGELATALGVGADPRECLYTGPGKTASEIANALGSGVRRFSVESEADLERVASVALAHGVTAECIVRINGLSPAGASGLRMTGMPSQFGFDLATSPPDWNRLLATPGARIVGLHFFPLTNAVDQESLFREFAASIDMAAQLRDEHQLALEFLDIGGGFGCPYAQPGERPTFPDLRAQLIEVLDERMRGWRDGRPEVAFESGRYLVGDAGTLLCTVTDVKVSKGKTYAVLDAGINHLGGLSGIGRVLPMARPEVVDGSQGGRPERAVNLVGPLCTSADLIGREVRTAVPEPGDILAIPNVGAYGLTASLMGFLSRPVATEVVVRRGHEPTASRLELRRTSIEEENNDA
>NZ_LT827010|6859610:6922095|6874397_6875540_-|WP_014693192.1|DBSCAN-SWA
MVLAPVHQRAQEWSFLQALSVLDGRPGAHDAARALAETELDFDYLTVQALRHHLAPAMWRFLVDNGIENRLSDPVLASFGSLAQICDYRTEELIDEASRVADAMAAAGARLAFTKGVVNQSTLYDNSGTRVMADIDLMIPPDSTAIITETLTSLGYSVAKEYDARTNSLVDLPRSRRMVYRMYPDHLPHFTKLTGNRAQPLIEIDVAFSLTWFSSAWQIPMDAVLRDLDSVLVRPGRSDRTLPTLTPAYSLLFIVLHLFREAWFITKKPVRLNQFADVVRLWRRIGANHASEIIKVVEDNGVGPAVGWVCHHVDAMFDTDMAATLGTERYAEPRWLTSGVAEDGSFVQWHGDMRARLAGGEPVIFTPAGEPPFGAAARGR
>NZ_LT827010|6859610:6922095|6886798_6887866_+|WP_080128088.1|DBSCAN-SWA
MVEPCRAARRSGQVADSNCPGGWDGSALTTPVLVFDLGGTWFRVGLSHIDGSVTLLGRYPAISRATHPELPVAELQQRMVSFIVDECVRHASTDVGISIGAAVNGHTGLVLSSAPLWGPGTWELPLTQKLCEALPAVRYSVVNDVSAQALSLLDETASSDSMAAALTVSSGIAYRTIDLASGHIPLDPDHGVQGEIGHLPSAFPWRGTYLSAVCECGVQDHVSAFSSGRAIEQLLPRLAGPDWNIAAFGEACRSGDALALELLDAFTLPLSTVLLYQATLNPQVRHTVLLGGVVDELGEIYRDSVLKNLARLGLYEVTSRDSGYFDRRIKIGNGDGLEALKGAGLYARRNGRAIQ
>NZ_LT827010|6859610:6922095|6906118_6906421_-|WP_014693226.1|DBSCAN-SWA
MEKIIVNHKHVAGADYSGQSIGQFSAQGSTFEDCRFDRSMLGQASFGSGTEQSYYVRCSFDRTSLTFLGGFARFVGRTFTTPALKLLTRSAESMFVSVAG
>NZ_LT827010|6859610:6922095|6861165_6861852_-|WP_099344198.1|DBSCAN-SWA
MTSGAVISAQERAAVEFMASLPTVRWDDIEAAAEVTERIARRLGDDREMLGALVDRVRRTPELRKKCECHALDDKIVIWDDPEKGLRIRLRLANTNQYERVHNHRYSFTAYILRGAYQHTLYATDQPLDDTADVDRFWPHFIREEPAGRCITLHHDQLHTTITEPETISLMIQSPAQKRRAFMIRRSDGHVWWREGAADETAERRAEVQMSDERFEHWVTRLKAFGVL
>NZ_LT827010|6859610:6922095|6882996_6884286_+|WP_014693199.1|DBSCAN-SWA
MMNRLAIRGGEAVRTAPWPVWPRPAEGASQALETVLHSGRWAISGPYRGTESFERQFARAFAAYNDSAHCIPTASGTASLMIALEACGVGAGDEVITPGISWVASLSTITAVNAIPVIVDVNPDTLCIDPDAVEAAITPRTKAIIAVHLYSAVADLDRLSAIADKYDITLIEDAAQAHGAAHRDRKVGTIGAVGAFSMQHSKVLTSGEGGATITSDGGLARRMEQLRADGRCLAKVPPRPGWMELEQVGEQMGSNRCLSEFQAAVLVAQLTALDAQNATRARNAMLLDKLLADDGCRPQQTSSGTTARTYYAYAVSLPEGALPGVPRELVGEAISAELGFPVKPPYLTLSRSKLYRPETRRRFALGADHLRRLDTSRFELPECDAANGRVLTFHHAALLGDEADMHDIAAAFAKVLRNGAVLSSVATGS
>NZ_LT827010|6859610:6922095|6895729_6896353_+|WP_052311962.1|DBSCAN-SWA
MGDHLADAEPQLAELTDHQRRLRRRFLQSRVVSVPQPWRPAKTPCTSVGGLQGVGFAADPASRRDLLLVTSSDGHGLFDAVSGQKLARDRDLDPGVPCPDGDLCCPGLGPIAATSVRIAGLHGGGLHTGTRDGWLIDVVSPDWPNQRVLLSYRSDPFSGEEGATWWHIFHSRFSELRAAGFSPSGSTLVVATSSDITVWTRERPPVA
>NZ_LT827010|6859610:6922095|6916150_6917206_-|WP_155123753.1|transposase|DBSCAN-SWA
MSADGESRVYAPIAVPKRAVSARYLSESERITIADEHRAGSSIRAIAALLDRAPSTISREISRNSDPATGDYHPFAAHQQAAARRPRPKPAKLQTNTELRDLVQELLNQRWSPEQICRALPLQHPDRPELRLTHETIYQALYRPDRGGLTRSRSPLLRTGRTYRKRRRSREQRTPRFTDSSNSIHDRPITADDRGIPGHWEGDLIMGAHNRTAIGTLVERSTRYVMLVHVPQGRNAAHFRDQLITAFSTLPTELRQSLAWDQGVEMGRHAEFTAATSTPVYFCDPASPWQRGSNENTNGLLRQYFPKSSDLSVHTAEDLTAVAAELNNRPRKTLGWDTPALRFARLLAEAA
>NZ_LT827010|6859610:6922095|6879397_6880879_-|WP_043515849.1|DBSCAN-SWA
MHSALDAAVANNAEASAINNGTERWSYSELQRQSFRFANWLIQLGVQRGDRVLVRLTNTREFAAILFGCSRIGAVMVPISTEMRQFHLRAVIGDADPRLVVTTDSDVPLMSQVTERPVHALSAVVEQMRKLPMTAPAVPTPAPNDLALLIYTSGSTALPKAVVCPHAQVAFAAHAIAAELGYQTDDVVLCRLPFSFDYGLYQLLLASIAGCEVFVPPADSPDLQLLQWIRRHGVTVVPIVPSLGQMLVRLAGRTSDQTSLRMITNTGAALNEDLIRQLQKAFPNVTIRLMFGITECKRVSILEGDGVLLRPTSVGRPLGGTSVTIVDDDDQPLPPGRTGQIVVRGPHVMAGYWNAPELTMQRFRLDRETGTVALYTGDYGYLDAEGYLYFAGRRDDLFKRRGTRVSVLEIEAAAVDIPGVRAAAVLPPTADGDLVMFVDAALTGPEVLREMSVRLEPAKVPSHCHVVASLPLTPNGKTDKKSLADHLLKGATS
>NZ_LT827010|6859610:6922095|6920958_6922095_-|WP_014693236.1|integrase|DBSCAN-SWA
MTVGSYELSNGKTNWYFVIDLPMGDDGKRRQHKRRGFPTKGSAKKAETEARKAYGDASIAADGSVAAELDGWLSERELDIEETTLDSYKNIIRMYVVPHIGGRQLYSLDKRVVQDMYKTLLREGGKDKKPLSPTTVRTTHRVLQQAFKDLGINLENVRQPRPAEREDHGRKGVWSPQQSKTFLRHHRDARLYAAWALAIVAGMRRGELAGLRWAKIDLDQGIVYVHIQRTICGNKVIEKSPKGKSRRPVAIGPAMVRVLREHKVRQDAEKAEAGLLYHDRDYVFPREDGEPYYPRYFTDMWEKACLEAGVRQIVLHDARHTSATAGADAGVPEHVMQKRLGHADGRTTREVYTHVLPESERKAAELMDSALQDWDEAA
>NZ_LT827010|6859610:6922095|6902289_6902820_-|WP_043512514.1|DBSCAN-SWA
MSVTDAAVAADLVPAGLEFLERVSDEVSLPLPPAPPYYSPASCGPEHGRFDSDEMVDVEDPEMPAKVNAGWLHMATEYGVLDSRREFLLNVNYSDPEEVEPEYAWVRVRLSDHWDLAGGHSTALRSGFGGLFTDRFVPEFSMLSTDHKAMLNTTVWGNGTVSTIVIRPDRREHTVD
>NZ_LT827010|6859610:6922095|6875730_6876666_-|WP_157432810.1|DBSCAN-SWA
MLLVDVDTAIETDWHGYEGHEDLVRVEDPPVEAWEALAGAGLLPKPEWLTWVADCQSSEDEFLGRMPRKERQSIAAARRRAAADGVRLRLGDLDSTYLDAFLPLYEARTAEKRHGWSVVSDIRGDLLADAADYFVVSAWRGDEFVGGCINLAPSEGAMRIRFSAVDQSGRYASLARALYLEAIREARVRGYRSVSLGTDPNLYGHVVEPGLLRFKSRLGFEPKPSHQVTGKPASDCADLVLGFAALMDPTIMFSYRTNAVSSTASELQAEIYSYSADVAVDQHTAALSFPVRRHVVDRRPTACATGNTAPR
>NZ_LT827010|6859610:6922095|6895147_6895396_-|WP_155123684.1|DBSCAN-SWA
MDPFKPAIDVMPLTEFDAPRKQRRTVKRIYDRLLAEEEMEGISYAAVCDYVHWRRPRIRVEAGRDPPQMFVPPSRKGRPSCR
>NZ_LT827010|6859610:6922095|6862623_6863742_-|WP_014693183.1|DBSCAN-SWA
MNTYTDQLALPIEVHCHGFGRVDFSEFATLDLEELDRQCAEEGVLSIPTLYLHRDRLTDFEQFMHRYHALRRAGRLPHVAGVALEGPLLASHGGTPKATVWAPTRHEWERLAKLGSLGLVYTVVSPDAFTAASGLYEALDDRHPRLDWIVPLLMEHGVRPALGHFTRADELASAELVHDIVEMAWQSEWTGQGARVVTDHLFNDMPLRIRHAFRTSAARKVRDSTLAAYDLPNWTLADMGEIAGPVPAVIMREAAAGRLSACINFDGEHVDLAIATRAVELMGYSNAMMMTDRCDSARIGGQALHQTEENGLWYQDGGIVAAGSQPLAKQMRNAQVNGISDADLWQLATSTAHRAFGTGVRTDLAALSVDSQ
>NZ_LT827010|6859610:6922095|6890553_6891370_+|WP_085945659.1|transposase|DBSCAN-SWA
MSKAWVVDDELWKLIEPVLPAWPARAPGPRPVPDRLCLQGILFVLHTGIGWEDLPQELGFGSGMTCWRRLQRWTEAGVFDQVHQILLDKLNAANRIDWSRAAIDASHIDAKKGGAGTGPSPVNRGKPGSKHHLICDGNGTPIYVLTSGANVPDIKRALDLLDCYPPIAGRLGRPRRRFAALLADKAYSSAAFRQACRERGTEPLIPKPKATGIKGLGKLRYVVEQTFALLHQFRRLAVRWERRLDIHDGFVSLACVLICWRRLINWTDQRSC
>NZ_LT827010|6859610:6922095|6908473_6909964_-|WP_043512521.1|DBSCAN-SWA
MTERAGGTTYYYTTTMTPDDRGRTTAITTPLNHTTKTSYNTADERTTTTDADGVLTEFRYDASGRTIAQIVGTMATGWTYDALGRTIAVTGHTVTNGVLSAPLRTSRTSYDRDSRVTRKTSAEGRITDYGYDGGGNVRTITQLRTPTDPASAVTVGLDYDALGNRTRTSDGNQHVTEYRYNDWGAPVEAVEPATAAHPAAMDRTWTFIYDQGAQAIRANLPGGVSVERDYDGLGQITTERGSGAEGASTTRSFDYDALGQLRKASTTGGDNTYSWNDRGLLTDVAGPGGTATYTYDAEGRLSNRSDGAGPAAFTYTSAGRLKTVTDPLIAKTLTYTYRPTGEVQTVSQGTGSLSRTYGYDNLGRLASDTLTKANGTQSAKLAYTYDRDDLLTGKASPESPATAPTLTATTASAGKPHGHDPTIRPSRTATTTLQTAPRSAPAPTPAPTHSTSATGCSPRPAAHNPAWLTPGHRAAPSAAPPKTAPPPPTRSTPSNR
>NZ_LT827010|6859610:6922095|6869606_6869969_-|WP_155123681.1|DBSCAN-SWA
MDGLSAAMFPRGRGMPLRKADAEALRGIGRDVAKAATTLQEAAKAVGSGLVPAPRHGRNCLIANRERDSHRACRGNECGREHFSCSGNPLQGGGRRNLLSLFSFATAGWSVPEEIVRASN
>NZ_LT827010|6859610:6922095|6901600_6901939_+|WP_014693219.1|DBSCAN-SWA
MAGQAGTPVEWDLEQFKVEAPRWRDAVHPPAEIYIKVERWWRLLKRVDARIEAVPVRPENNPEGNLWWMWVPDVEWEDEHGRGFRLSCYFRVYEKDDPPRLVCDEFRSERTR
>NZ_LT827010|6859610:6922095|6891876_6892317_+|WP_043515855.1|DBSCAN-SWA
MFSQTSVPFSQSGLTLKAVASQSKAAVSRAAANRIMIEAAKHKGKLYKFGAAGPKRFDCSGYTMYVYKKAAGKKLPHKANLQQRYGKAIAKSRARPGDLIIIRDGSYGTHAGIYAGGGMMWAAPRAGKTVTKQKIWSRNYVVRRLV
>NZ_LT827010|6859610:6922095|6865939_6866620_-|WP_043512499.1|DBSCAN-SWA
MAAFSVGLWSVGGDWARVMAIVVIVEALLMCLPWRVPRTMRSGVSFWAETLCGLLAPIVAVTMTVVTRPAWLTAGADWWWFGAAVAVAAGLIALSDLRLPSLLSGELAFVFGPTPRAHGAARAFATTVCAVGEEAVFRVPALLVSPAAPVGLLGAIAFVARHHIQPGTNRRGTIRSTMVEIAAGVLLLGLTVASGSIYPALLAHILNNIPNVILELQRENDDRGWT
>NZ_LT827010|6859610:6922095|6892919_6893594_-|WP_014693207.1|DBSCAN-SWA
MPHHYLQHLTTAPVAAAQQRYGSRAAIERMIAGWDTDALLGADEITFITARDGFYLATVNTDGWPYLQYRGGPPGFLHPLDPVAGHSVLAWADVRGNRQYLSVGNLGCSPRVSLFLMDYAHRRRLKILGTATVHDIRDGMPAHLAGRFGTLRTPGVVERLITVEVHSYDWNCPQHITPRWNEAELHDALAPIRDQLTQLQAENDALRDMVRRNRFQQHPSQETS
>NZ_LT827010|6859610:6922095|6917502_6917778_+|WP_014693232.1|transposase|DBSCAN-SWA
MPKPYPREFRDDVVRITQGRDPGVTVERIAKNFGVHPMTLFKWLRQAELDAGAEPGVSRNDSAELREARKRIKLLEQENEVLRRAAASQAA
>NZ_LT827010|6859610:6922095|6876698_6877886_-|WP_014693194.1|DBSCAN-SWA
MEHTLRSDVRQRAEAVLPTLAAHATRIDAEALFPVESLDCLRSSGLMGLLVPVEHGGLGGGIPDLIEVAGLLASRCLSTAMIWAMHCQQVDAVVQFAGPQLRAELLPRIAGGEVYLGSITSERTKGGHLFTSASPLEPAGDDFLLDRDAPIVTGGAYADGFLTTMLAAPDAPPTEVTLVYADRSQMAIDQRGTWNPLGMRGTHSVGLHLRGQVPGTQVVGEPGGFRHVAANSLVPLAHLGWSACWLGTAKGALRELLALRAPHRPRGLDPKSELVAARVARVRMELEVVSTYLTRVCQEVMERRANSRDLDEPATQIHLNTLKVIASESCFRAIDGIVEIAGLAQGYRRDAAVPFERYFRDLRSASLNYANDRLLVATGVLSMLDRSVRLSGEQT

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
6856817:6856834	attL	NA	NA	NA	NA
WP_014693179.1|6859610_6860432_-|tRNA	methionyl-tRNA formyltransferase	NA	NA	NA	NA
WP_014693180.1|6860428_6861169_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_099344198.1|6861165_6861852_-	hypothetical protein	NA	NA	NA	NA
WP_014693182.1|6861863_6862541_-	hypothetical protein	NA	NA	NA	NA
WP_014693183.1|6862623_6863742_-	hypothetical protein	NA	NA	NA	NA
WP_014693184.1|6863796_6864816_-	diiron oxygenase	NA	NA	NA	NA
WP_014693185.1|6864876_6865161_-	PqqD family protein	NA	NA	NA	NA
WP_014693186.1|6865160_6865943_-	hypothetical protein	NA	NA	NA	NA
WP_043512499.1|6865939_6866620_-	hypothetical protein	NA	NA	NA	NA
WP_014693188.1|6866724_6868926_-	asparagine synthase (glutamine-hydrolyzing)	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	1.5e-30	25.5
WP_155123681.1|6869606_6869969_-	hypothetical protein	NA	NA	NA	NA
WP_080128087.1|6870076_6871336_-	MFS transporter	NA	NA	NA	NA
WP_014693190.1|6871751_6872981_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_155123682.1|6872992_6874183_-	hypothetical protein	NA	NA	NA	NA
WP_014693192.1|6874397_6875540_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_157432810.1|6875730_6876666_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014693194.1|6876698_6877886_-	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_014693195.1|6877903_6878170_-	hypothetical protein	NA	NA	NA	NA
WP_014693196.1|6878159_6879401_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_043515849.1|6879397_6880879_-	AMP-binding protein	A0A2K9KZV5	Tupanvirus	8.5e-22	22.5
WP_052311961.1|6881670_6882111_+	flavin reductase family protein	NA	NA	NA	NA
WP_014693199.1|6882996_6884286_+	DegT/DnrJ/EryC1/StrS family aminotransferase	NA	NA	NA	NA
WP_043512502.1|6884290_6885925_+	hypothetical protein	NA	NA	NA	NA
WP_014693201.1|6885896_6886883_+	hypothetical protein	NA	NA	NA	NA
WP_080128088.1|6886798_6887866_+	ROK family protein	NA	NA	NA	NA
WP_014693204.1|6888987_6890082_+	L-threonine 3-dehydrogenase	NA	NA	NA	NA
WP_085945659.1|6890553_6891370_+|transposase	IS5 family transposase	NA	NA	NA	NA
WP_043515855.1|6891876_6892317_+	C40 family peptidase	NA	NA	NA	NA
WP_014693206.1|6892440_6892923_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_014693207.1|6892919_6893594_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_014693208.1|6893840_6894365_+	CGNR zinc finger domain-containing protein	NA	NA	NA	NA
WP_155123683.1|6894614_6895118_-	hypothetical protein	NA	NA	NA	NA
WP_155123684.1|6895147_6895396_-	hypothetical protein	NA	NA	NA	NA
WP_052311962.1|6895729_6896353_+	hypothetical protein	NA	NA	NA	NA
WP_014693214.1|6897992_6898298_+	hypothetical protein	NA	NA	NA	NA
WP_080128091.1|6900134_6900509_+|transposase	transposase	NA	NA	NA	NA
WP_155123685.1|6900537_6900813_-	hypothetical protein	NA	NA	NA	NA
WP_043515861.1|6901110_6901578_+	hypothetical protein	NA	NA	NA	NA
WP_014693219.1|6901600_6901939_+	hypothetical protein	NA	NA	NA	NA
WP_014693220.1|6901998_6902145_+	hypothetical protein	NA	NA	NA	NA
WP_043512514.1|6902289_6902820_-	hypothetical protein	NA	NA	NA	NA
WP_043512516.1|6904160_6904757_+	hypothetical protein	NA	NA	NA	NA
WP_085945605.1|6905290_6906096_-|transposase	IS5 family transposase	NA	NA	NA	NA
WP_014693226.1|6906118_6906421_-	hypothetical protein	NA	NA	NA	NA
WP_014693227.1|6906420_6906831_-	hypothetical protein	NA	NA	NA	NA
WP_043512519.1|6906842_6908567_-	hypothetical protein	NA	NA	NA	NA
WP_043512521.1|6908473_6909964_-	RHS repeat protein	NA	NA	NA	NA
WP_043512523.1|6910125_6913503_-	hypothetical protein	NA	NA	NA	NA
WP_014693228.1|6913741_6914233_+	hypothetical protein	NA	NA	NA	NA
WP_043515865.1|6914748_6915291_+	DUF4240 domain-containing protein	NA	NA	NA	NA
WP_155123686.1|6915590_6916154_-	hypothetical protein	NA	NA	NA	NA
WP_155123753.1|6916150_6917206_-|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.9e-30	31.6
WP_014693232.1|6917502_6917778_+|transposase	transposase	NA	NA	NA	NA
WP_014693233.1|6917897_6918092_-	hypothetical protein	A0A2L1IVS9	Streptomyces_phage	9.7e-11	54.9
WP_014693234.1|6919708_6919927_-	DUF397 domain-containing protein	NA	NA	NA	NA
WP_043512524.1|6920148_6920415_+	hypothetical protein	NA	NA	NA	NA
WP_014693235.1|6920486_6920885_+	hypothetical protein	NA	NA	NA	NA
WP_014693236.1|6920958_6922095_-|integrase	site-specific integrase	A0A2I7SCV1	Paenibacillus_phage	2.7e-28	27.9
6924284:6924301	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NZ_LT827010|9045686:9090307|DBSCAN-SWA
ATCAGAACACGGCTTTGTAGTAGTCCCAGCTGTAGCCGAGGAGCTTGCCGCGGCCGTTCTTCCAGGCACCCTTGCCGTTGGTCGGGTACAGGTAGAGGTCACCGTTGGTGCGGACACCGATCAGGTCGACCAGGTTGTCACCGTCGAAGTCACCCGGGGACATGAAGGTCGGCATGCCGTTCCAGCCGGTGCCGAGCTTGGTGCCGCGCGGGTTGATCCAGCCACCGTGACCGTTGCTGTTGTACAGCCACAGCTCGCCGGCGGCGTTGCGGCCGATCAGCGACTGGTGGCCGTCACCGAGCCAGGAGCCCGGGGTCAGCACGGTGTTGAACTGGTTCCAGCCGGAGCCGATGACCGTGCCCTGCGGGTTCTCCCAGCCGCCGGCACCGTCGCTGTTGTAGATCACCAGCGTGCCGTCGGCCTTGCGGCCCAGCAGGTTGGAGCGGCCGTCACCGTTCCAGTTGTTGGTCACCACGATGTCGGTGAACATGTTCCAGCCGCTGCCGATCTTGGTCGGCGTGGTGGAGACCAGATCGCCGCGGCCGTCACCCTTCCACTGCCACAGGGTGCCGTTCCGGTCCCGGCCGAAGATCGACTCGTTGCCGTCCGCGTTCCAGTTGGTGACCCGGAACAGCTTGGAGTAGGCCTCGTAGTTGTGGCTCTTGTCCAGGTAGCGGTAGTAGTTGAAGCCCACGTCGTACGACGACGTCTCGTCGATGTACGGCGTGCCGACCAGGGTGCCGGCGCCGGAAGCGACGATCAGGTAGCCGGTGCCCGGCTCCCGGACGATGAGGTCCGAGTGACCGTCACCGGTGAAGTCCAGGTTGGTCGGCTGGAGGTTGGTGACCTGCGCCTTGACCGCCCCGGAGAGCTGGTTCAGAGCCGCGTAGGCGCCGTAGTAGGCACCGCCGCAGACGTTGCCCCAGCTGGTGACGCCGATCTCGACGCGGGCCGCGGGGCCGCCGAGGAAGATCGGGCCGCCCGAGTCACCGTGGCAGGTGTCCTTGTGGTTGACCACGTCGCCGGCGCAGAGCATCGTCGTCGGGTCGAACTGGGTGCCGAACTGGCTCGGCTGGGTGCAGGTGCTGTCCTTCTGGGTCTGCACCGTCGCGGAGTGCAGCACGCCGGAGTCGCTGCCGCCCTCCTTGGTGATGCCGTAACCCACGATGGTCGCGTCCTGGCCGGCGGCCGGGTCGGCCGCCCCCTGGGCGATCAGGTCGGTCGCCTTGTAGACGTCGGGCAGCGCGTCCTTCAGGTCCAGGACGCTGACGTCGTTCTTCGGCGGGGTGTTCTGCGGGTCGGTGACCTGCGCCTGGTAGTTGTAGCTCGGGTGCAGCCAGGTGTTGGAGACCCGCGCGACGAAACCGGAGGTGTTGTCGGCCAGGTTGTCCCGACCGGCGATCACCTGGGTGTAGCCGTAGGGCAGGTCGACCGTGCAGTGGCCGGCGGTGAGCACCCGGGTCGGGCTGAGAACGGTGCCGGTGCAGGTGCTGGTCCACCACGCCGGGTTGCCGTTGGCGTCATTGGCGATGAAGTCGGACTGGATGCCGACGACGCCCGGGAAGTCCGCCGAGTGGGCGATGTCACCGTTGACGATCTTCGTCTTCGAGCCCGGCGTCTGGAAGGCCTTGGCGCGCTTGCCGGCCTTCAGCGGACCGGTCTTCGCCTTCACGGCTCCGGCCGGGATCTTGTCGTAGGGCAGTGCGAAGTGGCGGGCGTTCGCCGGAATTGGCGGCAGCAGCGCACTTCCGCCGGTGCTTCCAGCCGCCGAGGCCGGAAGCTGAACCAGCGCGACCGCAGCGGCCGCCACTGACACCCCCGTCAGCGCACTGGCGATGCGGCGACGCGTGGTCTTCTTGGGCACGCGAAGTCTCCTGTCGGAATTTCCCCGATTTGCCACGAGGCCAAGGGGGCCTCGTGACCCGGCGTACACCGCATGTCAGCGCTCGGTTGATCACAAGGGATGTCGATGGATCCGTGATCTTCCGTGGCTCGATGTAAGGCCGGGAGCGACACGCTAACAAGTCAGATCTTGACCTGGAAAGACCCTTTCACAGGAAAGTTGCTGTTTCGATATCAGCAAATTGGACGAAGCCCTGGCCAGCGGGTTTGAGGCGATCACCACTGGCGAAAAACTGTCCGAACGGCTATCTTGCGCCGCCGGAACGTACGGGTCCGTACCGGCGTCCAAAGACGGTTGTCGAAACAGGCCCTCGCGATGAATTTTCAGTGACTTTCCCGGACGGGAATCGGCGCTCGGTGCGGCTCGACGGAGACGATCGAGCGGCGTCCGGCGGGAGCTCTCCGCGACCGGTCACGACGGGGGTCGGCACGGCGTACCGGGCACGGGAAAGACCGCGGCGCCGGGCCGGAGCCCGGCGCCGCGGCGGGGTCAGGCGACCGACTTGGCGTTGATCGGGGCGACCGCGTTGCCCGGCTGGGCCGGCTCGGGGCGCATGCCGCTGCGCAGCGTCTCCAGCATGGTCATGCCCTGGGCGGCGAGCGAGGCGACGACACTGTTCAGGCCCTCGGCGCCGTCCAGAACGGTGACGTTGGCACCCTGCAGGCCCTCGGCGGCGGCGCGGAGCATCTCCGGCAGCTTGTCGATGATGGCCTGGTCCAGGGCGATCCGGTCCTGGGCGGCGGCGGCCTCGGCGGACAGCTTGGTGGCATCCGCCTCGGCGCGGGCCAGGGCGCGGATCCGCTCGGCCTCGGCCTCGGCCGGGCGGACCACCTCGGCGATCAGCTGGGCCTGACGCAGCTCGGCGTTCTTCTGCGCGACCAGCGCCTGCTCGGCGAGCACCTCCTGGGCGGCCCGGGCGGCGGCGAGCGGGCCGGCCTGGGACGCGGTCTGTTGAGCCTGATCGATCTCGGCCTGGAACTGGGCCTTGGCGATCGCCGTCTGCCGCGAGTACTCCGCCTGGTGGCGGGCGCTCTCCTGCTGGGCCATCGCGCTCTCCCGGTCGGCGGCGGCCTGGGCGACCTGCGCCTCCTGGTTGACCCGGGCCTGGTGCGGTGCCGCCAGCGCCTTGATGTAGCCGACACCCTTGTCGTCGATGCTGCTGATCTGCAGAGAGTCGACGGCGAGGCCGATCCGGGCCATCTCGGTCTTGCTGGCGTCGACGATCGCGTCCGCGAGAGTCTGCTGCTCCCGGATGATCGACTCGACCGTCATGCTGCCGATGATGCTGCGCAGGTGGCCCGAGAAGATCCGGCCGACCAGCGTGGGCATCTGCCCCTGGTCGCCCTGGAACCGGCGGGCGGCCGCGGCGATCGACTCGTGGTCGTCACCGACCTTGAACGCGATCACCGCCTGCACGCCGAGGGTCAGGCCCTGCTTGGTGTAGCAGTCCTCGACCACCTCGGCCTCCTGCATCGCCAGCGTGAGGCGGGTGGCCTTGGAGAAGACGGGCATGACGAAGACGCCATGTCCGGTGACGATTTTGAACGGCAACGCGTCCGCACCCCGCTGTTTCCGACCGCTGATGAGCAGCGCCTCGTTGGGGGCGGGCACCCGATAACCGAACATTCCTACAGCCCTTCTTCGATGGGCCATGGCTCGACGTCGATTTGGCGTGCGCCACGGTGATTGATGACGAGCACCTCGGAACCGGGAGGAACGGGTGCGGCCGCGTAGGCGAGGTAGTAGTGCGCGATACCGGCGACCACCAGACGCACCTCCCCCGCACGCTCGCCGCCGCGGATCGCGGTGATCACCGTTCCGATCCGGCCGACCAGCGTTTCTCTCGTCACGCCTGCATTGTGCTCCTGCCGTGCGAGCCCGCGCCGCCCCATTCAGCCGGCGGCCGGTGGCCTGGTGGAGAGCAGGGCACGGGCCTGTTCGGCGGCGCGGACGATGCTCTCCCCGACGAAGTCGGCGAAGCGGGCGATGTTCTCCAGCCGGGCCGCGGAAAGCGTGTCCGGACCGAGCAGGCGCACCCCCTCCCGAGCGGTCACCGCGAGCCGTTCGTTGGCCCGGGCGCTGGCGATCATCGACTGATAGAGGGCGTCGTCGTCGACTACGTACCGTTCCCGGCGACTTTTGTCGCGCTCGCGGCGGATCAGGCCGAGACTCTCCAGCAGGGCGACCGCTTTGGACACCGAGGCCTTGCTGACCTGCAGGCGGCCGACCAGGTCGGCGGCGGTCGGGCTGGTGTCGGAGGTGTAGAGGCAGGTCAGCACCCGGGCCACCATCCGGGGCAGGCCGGAGGCCATCAGGACGGCGGTGAAGGACTCCTCGTACTCCCGGATGGCGGCGTCGTCGCGACCGGAGGGCGACGCCGGTGTCTCCGGGCCGCGGGCGGCGGACTGCCGGCGCCGGCGGACGCGGCGCTCGGTGGCGTGCTGGGCCAGGTCGGCGCGGTAGCCGGCCGGACCGCCGTTGCGCAGCACCTCGCGGGTGATCGTCGAGGTGGGCCGGTCGAGCCGCCGGGCGATCTCCGCGTAGGCGAGGCCGTCGGCCAACCCCAGCGCGATCTGATGACGTTCCTGCTGACTGAGCCTGCCGCCCGGCATCGTGCACTCCCTCTCCCCGGTCCCGGCTCAGCGTAGCGTTCACCGCTATTCCATTGCAACGGCGTTGCATTCACTTTCATCACCATTGCAATGATTTCCTAACCCTGAGCTGCAGTGATGCTTACCCATCGCAACGAGTATGTTGCCCGTTCTGCGAACGCAACGTAGCGTTTCTCATGTCAGAAACACCGAGCAGACAGGGCAGAACGATGAAGAAGTACGACACCCGCACCGCCATCGCCGCCGTCATCGACATCCCGGCCGGCCGGGTCCAGGTCATCGCCGCCGACCGCACCGACACCGTGGTCGAGGTCCGGCCGCTGGACGCCGCGAAGAGCCGCGACGTCAAGGTCGCCGAGCAGACCGCGGTCGACTTCACCGACGGGATCCTGCGGATCGTCGCCGAGGCGAAGAATCAGATCTTCGGGGCTTCCGGGTCCGTGGAGGTGACCGTCCAGTTGCCCGCCGGCTCCCGGGTCGAAGTGCGGGCGGCCAGCGCCGAGTTCCGTGGCGCCGGCCGGCTCGGCGACGTCGTCCACCGCGGCGCACACGGCGCGATCAAGCTGGACGAGGCGGCGAGCGCCGACGTCAGCACCGACGCCGGCGACGTCACCATCGGACGGCTCACCGGGGCAGCCGAGATCAGGACGCAGAAGGGCGACATCCGGATCGCCGAGACCTCCGGCGGCGACCTGACGCTGAGCACCCAGGCCGGCGACATCACCGTGGACACCGCGGCGGGGGTCTCCGCCTCGCTGGACGCGGGCACCTCGTACGGCCGGATCGTCAACTCGCTGCGCAACGCCGGCGGCGAGGTCGAGGTGGCGATCCGCGCCACCACCTCCTACGGCACGATCACCGCCCGCAGCCTCTGACGATCCTGCGACAGCGCCCGGCCGAGCGGCCGGGCGCTGCGCCGCTTCAGCGGTCGGCGCCGCGCAGGATGCGCAGGAGGAAGCGGAAGACGTCGAGGAAGGGGCCGGCGCGGCAGGGTCGTGCCGGGTGGCGTGGTGATGTCCCGGCCGGTACGTCCGCGACGCGCGATCGGGCGCGGACCATGGACGTACCGGCGAATCGGGTTCTGTCAGTTGGTGGTGGGTTCGCCCGGGACGTTGAAGAGCGGGTGCCAGGGGTCGTCGGCGTCGATCGGGAACTCGGTCGACGGGGTCTCGCCCTTGGTGGTCCACTTCGCCTCGTACGGCAGGCCGTTCAACAGGACCCGGTCGCCGCGCTGGTAGGCGGTGCCCGGGGTCCAGATCCTGGTGACTCCGGTGACCGCCGGGGTGGGCTTGGGGGCCTTCTCGACCGGGCTCACCGGGCCGATCACCGACCAGGCGTTCTGCGTGCCGGCGGCGGGTGCGGCGGACGGGTCGACGCCCGAGTTGGCCCACTTCGCCTCGTAGACCACGCCGTGCCAGACCACCTTGTAGCCGCCGGTGTAGAGGGCGGTCAGGCGCCAGATCGGGTACGGGCTGGTCTTCGGGTCGTCGACGGTGGCCGCCTGGTTCGGGATGTCCACCGAGTCCTGGCTGCTGCTGCCGGCCGCCTTGCCGGGCAGACCGGCGAAGACCTTGGAGAAGGCCAGCGCGTCCTGGTCGACGCCGCTGCAGGTGTTGGAGTGCACGACCACGTTGGCGAAGGTGCCGCGGCAGGGCGCGTCCCGGTTCAATGACCACATCGAGACCCGGCCGAGGCCCTTGTCGACCGCGAACGTGGCCAGGCCGGTGGCGTTGTCGACGGTGAACCGTTCGGCGTCGACGTCGTTCTGGCCGATCATCGGGGTGGCCCCGATCCGCGACCAGACCTGCGGCGAGGTGAGCTTCTGACCGAGCCGCAGGTAGAGGTCGGTGAGCTGCTTGTGGGTGCCGTCCAGCGCGCTGGTGCTCAGGCCCAGCATGTTCGGGTGGCTGTCGCCGTTGTTGAAGTCCATCGTCATCACGTTGACGCCGCGCAGCGCGACACCGCCGTCGAGCATGCCGCGGACCACGCCGACCCCGTCGTCGGTGAGGCCGTTCGGCGTCACCGGCAGGGTCAGCCACACGGCGAGCGGCTTGCCGGCCGCCTCCCGCTCCTTCTGCACCGCGGCGACCGCTGTCACGCGGCGCTGCAGGGACGCCTGGTCGGCCACGGCGGTGCCTTCGATGTCCAGGTCGAGCGTCTTCACGTCATAGCGTTTCACCAATTGGCGGTACGCGTCGGTGAGCTTGGCCTGGTCGGCACACGCCACCGCGAGCTCCTGGTTGGCCAGCCCGCCGAGGCTCAGCGTGATGTCGCCGCCGGCCTGGCGCAACTGGTCGATCCGGCGGTCGAGTTCCAGCGAGGTGGCCGCCGCGTCCAGCGAGTAGGCGCCGCCCCAGCTGGGGGCGCAGGCGCTCTTCGGGTCGGCGACGACGAAGCCGAGGGCCACGTTCTTGGCCGGGTTCGCGGTCGGGTCCTGGAACTGGAAGGTCGGGGTCAGCGTGACGTCGACGTACGGCACCGCCCAGGACTTCGCGGTCGGACCGGAGGTGTCCCGCAGATGCATCACGCCGAGGGTGCCGCCGGCGCCGACCGCACCGAGCGCGAGCACCAGCATTCCCAGCCTCGTCCACGACAGCCGGCGGCGCGGCTGCTCCGGTTCCTGCCAATCCGGGTCGGCGAGCGGATCGATACCCGTTCGCGCGGCTACGGCTGTGGCGCGGTCCGTCATGAAAACCCTTTCCCTGGAGTCGCTAAACGCTGACCCACATCCGCGATTTCCGCGATCGGGTGAATGGGGGAAGTCGTCCAATCTGGAATCCGGAGCGCCAGATCCTGATCTTGCGATGACAATTCCGCCGGATGCCGTCTCTCCGCGTCATCGCAATTCGCACCGAAGGGCCCAAACACGCATGTCATCCACATCGGCGGACCAGCGCAAGCGGGACGCCCAGCGACAATGGGGCGCCGACCGGCGGACTGATCCTCATCCGATCGTTCCGCCCCCGGTATCCGAAGGCAGGATCACCCGGGGCCGGCTCGCTATCGTGGTGACCATCACGGTGTGGGCCGGTTACATCGCCTATACGATTTTCGAGCAATTCATCGTCGGTAAGGCGTACAACGCACGGCTGGGTGCCGAGGCGATCGCCTATATGCTCGTCATCACCGGTCTCGCCGCTTCCGCAATCGCCTACCTGATCACCCGGATCGGCTACTTCTATCGTGGCCGCGGTCACCAGCGGGCGCCACGGATCATGCTCGACGAGTTCATCGGCGGCAAGACCCCGTCCTTGACGGTTTTGGTGCCGTCATATCAGGAAGACGAGCGGACCAACCGCAGCACGCTGCTCTCCGCCGCTCTGCAGGAATATCCGGGGCTGCGGGTCACGCTGCTGATCGACGACCCCCGGGCGCCGAAGACCCGGGCCGCCCGGGACATGCTGCTGGCCGCCCGGGCGCTGCCCGGCAAGATCGAGGCTGAGCTGCAGGTTCCGTACCGGCGGGTGGCGGCCGCGTTCGCGGCCTTCGACGAGCAGGTGCGGTTCCGCGGCGGCCATCTGGTGGTCCCGGACGACATGCGCCGGCTCGCCGACGAGTACCGGTTCGCCTCCGACTGGCTGTACGACCTGGGCGCCCGGCAGGAGATGGTCGACCACACCGACACCTTCTTCGTCGAGCACATCCTGCACCCGCTCGCGGTCGAGCTGGGCCAGATCGCCGGCGCGCTGGTCAAGGGTGCCGACGAGCAGGTGGCACTGCCGCTGCCGCGGATGAACCAGCTGCACAAGCGGCTCCTCGCGATCTTCGACGCGCAGGTGACCAGCTTCGAGCGCAAGAAGTACGTGTCGCTGTCGCACGAGCCGAACAAGGCGATGAACCTCAACAGCTACATCGGGCTGATGGGCGGGGCGTACCAGGAGGTCAACACCCCGCTGGGAACCGCGCTGGTGACGGCCGGGCCGAACCGGGCTGATCTGGTGGTGCCGAACCCGGACTACGTGCTGACCCTGGACGCCGACAGCGTGCTGCTTCCCGAGTACGCACTGCGGCTGGTCCACCTCATGGAGCAGGGGGCGTTCGCGCAGCATGCGGTGGTGCAGACGCCGTACAGCGCATATCCCGGCTCGGGCACCCGGGTGGAGCGGATCTCCGGCGCGACCACCGACATTCAGTACATCGTGCACCAGGGGATGACCCACTACGGTGCGACGTTCTGGGTGGGGGCCAACGCCGTACTCCGCAAGAAGGCTCTCGACGAGATCTGCGAGGTCTCGTACGAGGGCGACTGGGAGATCAAGCGCTACATCCAGGACCGGACCGTCATCGAGGACACCGAGTCGACGATCGACCTGGGTGTCCGCGGCTGGACCCTGCACAACTACCCGGAACGGCTCGCCTACAGCGCGACCCCGCCGGACTTCGGCTCGCTCGCCATCCAGCGGCAGCGCTGGGCCAACGGCGGCCTGCTGATCCTGTCCCGGCTCAAGGACCAGTTCAAGGCGAAGAGCAAGCGCGAGGACAAGAACCGGTTCGGCGAGTACTTCCTGCGGGTCAACTACATGGCGTCCATCTTCTGGAGCTCCATGTGCCTGGTGATCATGCTGGTGTACCCGTTCAACAACGAGCTGCTCAACCCGTTCCTGCTGCTCATCTCGGTGCCGTACTTCTTCATGATGGCGGCCGACCTGAAGCACCTCGGGTACAAGCGGACCGACATGCTGCGCATCTACGGCTTCAACCTGATCCTGCTGCCGGTCAACCTCTCCGGCAGCATCGCCTCCCTGCTGCAGCTGCTGACCGGCGAGAAGAGCGCGTTCAAGCGGACGCCGAAGGTCCGCAACCGGACCACCACCGCGACCAGCTACCTGCTCCTGCCGCTGGCCCTGGTGGTGCTCTGCCTCTACACGGTGTGGCACGACGTGCGGCTGCACCAGTGGAACAACCTGGTCTTCGCCGGCCTGAACCTGGTGCTGTCGCTGTACGCGGTGATCGCCTTCATCGGCCTCGGGAACACCGTCGTCGACCTGGCCACCCATCTGCGGGACTGGCTGGTGCCGGTGGCCACCCCGAAGAAGGTCCGCAAGTCCTCGGCTTCGAAGAAGGCCGCCGCGCCCAAGGCGGCGGCGATCGGCGACTGGGCCACCGTGCTGCACTACCGGCACGAGACCGGCGCCACCGCCGGGCAGGTCACCGTGCGGCTGCAGCGCACCGACACCGGCGCGTGGAAGACCGACAGGCCCACCTCGGCGAGCCGGGCGCACCTGTTCGAGGAGTTCAGCTTCTTCACGGTGTTCCAGCCGATCCACAACATGATCAACGGGCACGTGGTCGGGTACGAGGCGCTCACCCGCTTCGCCGACGGCAGCAACCCGCGCGAGGGTTTGGAGGCGGCCGCCCAGCGCGGCGTGCACGTCGCCCTGGACGCCGCGCTGGTCCAGGCGGCCATCGCGTCGTCGTCGTCGCTGCCGAACGGCACCTGGCTGGCCGTCAACGTCTCCACCGACCTGCTGCGCCGCCCGCACGAGCTGGCGCCGCTGCTCGCCGAGGCCAAGCGTCCGCTGATCGTCGAGGTGGGCGGCCCGGTGCCGGCCGAGGTCGGGCAGCTGGGCGGAACCGTCCGGCTCGCGGTCGACGACCTGGGGTTGGGCTACGAGACGCTGGCCCTGCTCGAATCGGCCCGGCCGGCGTTCCTCAAGCTGAGCCTGGACACGGTGCAGAACCTGGAGAACGAGACGGCGCGGCAGGCGTCGATCCGGACCCTGGTGGAGTTCGCCGAGCAGCACGGCTGCACGATCATCGCCGAGGGCATCGAGACGGCCGCGCAGCGGGATGCGCTGGTGGCCTGCGGGGTGCCGTTCGGGCAGGGCTTCTACCTGGGCAAGCCGGTCCCGGTGGAGCGGGTCCTGGCCGGCGTCGGCGGCTGGTGACACGCGTACAGCCGGCAGCATGAGAGGGGCCGTGACCCGCGGGTCACGGCCCCTCTTCCGTGCCCGGCCCGGGAGACGCGAAAGAGGCCCGGTCCGCGTCGCCGCGGGCCGGGCCTCTTTTCAGATCAGTTCAGATCAGCTGGTGAAGCGGGTCCGGCGACGACGGACCAGCATCAGCGCGAGGCCGCCGATGACCAGCAGGACCACGCCACCGCCGGCGACCGTGCTGGCGGCCGAGCCGGTCAGGGCCAGGTGGCCACCGGACGTCGGGCTGGTGCTGGCGCCCGGGACGGCCGCCGACGGGCTCTGCGAGGCCTTCGAGGTGGACGCCGACGGCTTCGGCGAGGCGGCGGTGGTCGTGGTGACCGGGGCCGGGGTGAAGGTGGCCTCGGCGGACGCGGTGACCGGCTTGCCGATGCTGGAACCCAGGATCAGCTTCTGGTGCTTGTCCTTGCCACCGCTGTACAGGAAGACCCGGCCGAACGAGACGGAGTCCTCGGCGTTCAGGGTGACGGTGGCCTTGCCGGCGTCGGCCGCGGTCAGCCAGAACTTGCCGCCGTTGCTGGTGCTGGTGACCGGCTTGCCGTCGGCGTCGACCGCGGAGCCGCCCTTGACCGAGACGCTGATCGCGCTGGCCGGACCCGCGACGGTGAACGGGCCGGCCTTCTCGCCGGCCTTGGCGGTGGCGCTGGCCGGGGTGACGGTCAGCTGGGCGGCCGGCTCCGGCTGGTCCACCGCGTTGGTGGTCAGGTAGTCGTAGATGCCCTTGACCACGTCGTACTGCGGCTTGTCGGTGAGCCGGGCGCCGTCGGAGTACGCGCCCAGGTCGATGCCGTCGCTGAAGTGCCAGACGGCGGTCTGGGTGCCGAAGTACAGCAGCTTGCGCTGCCGCGCCTCGTCCAGCTGCGGCATCTGCACGTGGGCGGCGGTGAGCAGGGCGTTGATGTCCCCGTTCGGGTAGCCGTGGGCGAGCACCCACTGCACCTTGGTGAGGTTTTTGACCTCGGACTCGTCCCAGGTGCCCTCGGTGTACGGCTCGTTCGCCGCGAGCCCGGTGTGGTAGTCGATGCAGAAGATCGGGACGGTCTGGCCCTTGATGGTGAACTGGATGCCACCGACCGAGTGGGCCTTACCGCCCAGCACCAGGGTGACGGCGCCGTCGGTCATCCGCGACGGAACACCGGTGGTGGGCTCGTCGGCGGCCGCGGGGGCAGCGGCACCGAGCAGCAGCGCGCCGCCGGCGGCAGCGGCCATGGCGACCTGCGCCCAGCGCCGTCCTGATCGTCCGAGCATGTGTGGAACCTCTCTCCAGGGTTGGGGGGTAACCCGCTTTGTGGCCAGCCAGGAATCGACGCTTCTCATTCCTGCGGCGCCCCATATTACGTCGGGACCTTACCGTCGCGACGGTGCGGGTGCGGCTCGTCCGTTTGCATGATCCAATAGCGCCCATTTCCCGGTAGGGTCAAGCCCCTCGGGCGCCGGGAACGCTCCCACCTGGGCTTATCTCCACATCGGACGCCGCTCGTCAGTCAGCGACATTGACAGTGGCGATTCCCCTCCCCGGATTGAGAGCGCTCTCAAAACGCCTGTAGGAGTCCCCATGCCCCGTGCAACAACGTTGTTGAGCACGTTCACCGCGCTCGTCGCCGAGGTCGGGGGCCCGATCGCACGGACCCCGTACGCCGCGCTCGACTGCTCAGCTCCCGACCGTCCTTAACGAAACTCTTACCGACTGCGAGCGGGGCGCTGACCCGCGGTCCGCAGGATCGTGGTCATGAAGCGAACCCTGGCTGTCGCGCTCATGCTCGGCGCGCTGATCACCGGCGGCTGCGACCGTGGCGCGCCACGGGCGACGAACCCGCCGGCTCCGGCGGCGACGCAGGCCGATGACGGCGTCGACTCGCTCCTCGACGACGCCGGCACCCAGCTCAGCCACGACGATCAACCCGCTGAAGACGAGGATTGAGGTCCCCCATGCACCGTGTTCTCACCGCATCCCTGATCGCCGCGCTCGGCGTGTCACTCGCCGGGTCGCCCGCGGAGGCCGCCGCGCTCGGCGGGTCGCCCGCGCAGGCCGCCAAGCCCCTCGACGTGGTAAAGAAGGCGGTGGCCGCCCGGATCGACAAGCGGCTCGACGCCCTCCGGAAGGACGCCGCCGCGCTCGGCGGGGCCAAGCACCTGCAGGCCGCCCACAAGCAGGCGTTGCAGCAGCTCATCGACGGCCAGTCGGCCGGCCTGACCGCGTTGAAGTCCAAGGTGGAGGGCGAGACGACCGCCGCGGGGCTGAAGGCGGACGCGCGCAGCATGGTGGTCGACTACCGGGTGTTCATGCTGACCGGGCCGAAGGTGCGGCTGTCGGTGGCGATCGACGCCGAGCTGGCCGCCGCGGACCGGCTGCACGACCGGCCCGGCGCCGACGACGCCAAGCTCGACGCCGTGCAGAAGTCGCTGGCCGGCAAGGTCGACGCGTTGCTCGCGATCCAGCCCGGTGCGGACGGTGCGGCGGTGCGCGCCCAGGTCACGACGATCCGTACGACCGCGAAAGGGGCCCGCAGCGACCTGAAGGCGATCAGCGGGAAGAAGTAGCGCTGCCGTAGCGGGCGGACCGCCCCAACTGCTCCTCGATCCGGATGAGCTGGTTGTATTTGGCGGTCCGGTCGCTGCGCGACAGCGAGCCGGTCTTGATCTGGCCGCAGTTGGTGGCCACCGCCAGGTCGGCGATCGTGGTGTCCTCGGTCTCCCCGGACCGGTGCGAGATCACCACCCGGTAGCCGGCCCGGTGCGCGGTCTCGACGGTCCGGAGGGTCTCGGTCAGCGTGCCGATCTGGTTGACCTTCACCAGGATCGCGTTGGCGTACCCGCCGTCGATGCCGCTCTGCAGGCGATCCGCGTCGGTGCAGAACACGTCGTCGCCGACCAGCTGGATCCGGTCGCCGGCCTGCGCGGTGAGCTTGCGCCAGCCGGCGAAGTCGTCCTCGGCCATCGGATCCTCGATCGAGCTGATCGGGTACGCCGCGGCCAGCTCCAACAGGTAGTCGATGTGCTCGTCAGCCGTGCGGGTGCGGCCTTCCCCGGTGTACTCGTAGGCGCCGCCCCGGTAGAACTCGGAGCTGGCCGGGTCGAGACAGATGGTGACGTCGATGCCGGGCCGGTACCCGGAGTCCCGGACGGCCTGGACCACGAAGCGCAGCGCCTCGTCGGCGTCGGCGAAGTTCGGGGCGAATCCGCCCTCGTCCCCGACGTTGGTGCTGTGGCCGGCCGCGGCCAGCCGGCGACGCAGCGTGTGGAACACCTCCGACCCGATGCGTACGGCCTCGAAGAAGTTCTCCGCGCCGATCGGCGCGATCATGAATTCCTGGAAGTCGAGCGGGTTGTCGGCGTGGGCGCCGCCGTTGATGATGTTCATCATCGGCACCGGCAGCGTCCGGGCGCCGGCCCCGCCGAGGTAGCGGTACAACGGCTGCCGGTGCGCCTGTGCCGCGGCCTTCGCCGTCGCCAGGGACACCCCGAGGATCGCGTTCGCGCCCAGGCGTCCCTTGTCCCCGGTACCGTCGAGATCGATCATCGTCGTGTCGACGAGCGCCTGGTCCTCGGCCTCCAGCCCGGTCACCGCCGCGGCGATGGCGCCGTTGACCGCGGCCACCGCCCGGCTGACCCCCTTGCCGTGGAATCGTTCCGGGTCACCGTCGCGCAGCTCGACCGCCTCGTTCGCCCCGGTCGACGCACCCGACGGCACCGCTGCCCGGCCGGACGAGCCGTCCGCGAGCACCACGTCGACCTCGACGCTCGGGTTGCCCCGGCTGTCGAGGATCTGCCGTCCGATCACCCGGCTGATCGCCGTCATCGCACTCTCCCCTGCTCCTGTCACGTCTGCCCGACCAGACTCGCCGGTCGCCGGCGGCCCTGTCATCGCGAGGAGAATCGCGTTGACCTGTACCCGGGGGTACGGGTTTAGGGTCGGGGCATGCGCGTGGGTGAACTGGCCCGTCGGACCGGCACGACGATTCGGGCGTTGCGTTACTACGAGCAGGTGGGGCTGGTCGTGCCCCGCCGGCTCGGCAACGGTTACCGGGATTACGAGCCGATCGCCGAGCGGCAGGTCGCCCAGATCCGCGAGCTGACGGCGCTCGGGCTCACCGTCGAGGAGACCCGCCCGTTCGTCGAGTCGATCGCCAACGACGACGACGTCTGCGCCGCCGCGGTGGCCACCTTCCGCAGTACCGTGACCAGCCTGCAGACGCGCATCGGTGAGCTGACCACCCAGCGGGAGGCCCTCGACGCCCGGATCGACGCCGCCGCGCACCGGATCGTCGCCGGCACCCCGGTCACCGGCGGGCCGCCAGCCGGTCTGATCGGCCGACGCCTGCCGGAGCTGCACTTCTACGCCACCGACGGCCGCCCGCTCCGCCTGGACCACCTCGGGCCGGGACGCAGCGTCATCTTCGTGTATCCGCTGACCGGTCGGCCCGGCGTCGACCTGCCCCGCAGCCTGCTGGAGATCCCCGGCGCCCGGGGTCAGGGCGACTGGCTGCGCGACCACCACGCCGAGATCCGCACCGCCGGAGCGGCCCGCGTCTTCGGCCTGTCCGCCCAGTCCACCGGTTACCAGCGCGAACTGGTGCACCGGCTACGGCTGCCGTACCCGTTGATCCCGGACCCGAAGCTCACCCTGGCCGCCGCCACCGGCCTGCCCGTGCACACCACCGGTGACCTCGCCGTCTACGAGCGGCTGACGCTCATCGTCCGGGACGATCGGGTGGAACACGTCTTCCACCCGATCCCCGACCCCGCCTCGCACGCCCTGCACCTGATGCGGTGGCTCACCCAGCGCCGGTCCGGCGGGTAACCCGATCGTGCACGCCCCCTTCCGGTGACGCCGCGGCTGCGTAGCATTCAGGGCGGGAGGCTCTCATGTCGACGTCCCAGCCCGGTCTCGTGCAACGATCGTCGTTCTCGTCCAGCGACGAAGCCGAGGTCACCGAATTCATCCGGCAGATGTAGGCGGAGAACAGGTCCCGCTTCGCGCCGGTCCGCAACGGCGCGCGCTTCTCGGCGCTGACCCACGACACCCCGGTGATCGGCGCCGACCGGGTGCGGACGTCCATCGATTACGGCGGCACCAGCGGTACGGGTTTCCACGACTACGTGTTCTTCGTGGTGCACACCGGCAGCGTGCAGATCGACAGCCCGCTCGGCGGGACCGTCGCATCCGCTGCTGACGTCGCGTTCTATCCGCTCGGGTTCCGATCGAGTTCGACATGCACCACTTCGACGTGACCACCCTGCGACTGCCGGCCGATCGGATCAAACGGTCGCCGAGGACACCGCGGACATGCCGGCCGCACAGACCCGGTTTCACGGCATCACGCCGGTTTCGGCGTCGATGGCCCGATACTGGCGGTCCCTGATCGCCCTGGTCAGCGGGGCCCTGAGCGATCCGGTGTCACCGTTGAACTCGCCGCTGCTCGCCGAGGACCTGGCCCGGACGGTGGCAACCGGCGCCCTGCACGTCTTCCCGAACACGACCATGGGCCGGCAGCATGTGCCCGGTCCGGGCGCCGTCACGCCGGGCGCCGTCCGCCGCGCCGTCGCCTTCGTCGACGCCGACGCCCACCTGCCTGTCCAGCTGAGCGAGATCGCGGCGGCGGCCGGGACCAGCGCCCGTGCCCTGCAATACGAATTCCGCCGGCACCTCGGCACCACCCCGCTGCGATATCTGAGCCGGGTGCGCCTCGAGTTGGCGCGCCAGGAGCTGCATCGCGCCGACCCGACCCGCGGCGACACCGTCGGCGCCATCGCGGCGACACCGTCGGCGCCATCGCGGCCCGGTGGGGTTTCGCCAACACCGGCCGTTTCGCCGCGGCCTATCGAGCCGCTTACGGCGTGTCCCCGAGCGAGACGTTGAGGAGCTGACGCCGCGCCGCGGGGTACGACCCGGTGACCCGCGCGGACGCATCCTCGGCGGCCCGGTGGGCGACCGCGGCCCGGTCGATCAGCGTCTGCGCGGTACGTTCCAGCTGGTCGGCTCGGGCACGCGCGCGTGCAGCGAAGGCGAGGCAGGCGGCCGCCCGCTGGCCCGGCGTCCCGGTGAAGTCGGAATCCAGGCTCACGGGTGTCATCGAGCTCCGCTGAGCGGCTTGCCGTCAACGCCGGCCAGCCGGCCGCTTCGTTCACCGGCCCACCGCTTCGCTCCCCGGCCTTGAGGGTTCGACCGCTTCGCTCCCGGCCTTGAGGGTTCGACCGCGAGAAGACCGGAGAGGCACGCTGCATCCGGTGGTGAAGCCGGGGGTCCGGGGAAGGCCGACGGCGCGACCACCGGACATGTCCCGATTCTCGTCTCGCTCAGATGCGCAAGGGCCTTGCCGGCATGCCGGGCCAGCGACTCCTGGACGGGATACCGGTCCGGCGAGCGGTACAGCAGTGACAACAGCCCGAGCCGTGGTCCGTCCCCATCACGCATCGGGTAGCACTGCACCGCGCGGAATCCCGCATCGAGCAGCATCCGCGTCGCCAACCGGCTCACGCCGACGACGGCGGCGCTCAGATCGTGGACCACCACCGGGCCGGCGCTGTCCCCCTCCGGTGGGACGACGGAGGCGACCGCCGAGCCGATCCGGGCGACCTGATGCGGGCCGGATTCCGGCAGGCCGCGGTGCCGTGTCAGCCGCAGCGGAGCCGCGCCCGGAGCACAGGTGTGCAGCAGGAGCGCATCCGGACGGGCGACACCGCTGACTGCGATCATGATGGCGGTGTGGACGGCGGGCTCATCGGCCAGGGTGAGGAAGGCGGTGCTGGACAGCGTGCCCACGTCAGCACGCAGGCGCAGGCGGAACTGGGTCAGGATCGCCCGCCGGGTGGCGCGTATCTCCGCGTCGATGAGGCCCTGTTGGATGCGACCGCGCCGCGCCAGAAGGGCCTCGACCGTTACCGAGGCAGACCTGGCAGGAGCCGGATGTCCGGACGACTCTCGCATGGCCACCGCCTTGAGGGAGGCTGTCGCCCAAAGGCTACGCCCACCCCCAGGCCGCGCCCCACAGCACTCGGGAGTGTCCCGGGTGCTGTGGGGCCGGGCGTCACCGGTAGTACGTGCCCGGGTTCCGGCGGCGCGGAAGGAGGGCGAGCACCGACAGACCGACCAGGGTCAGCAGCACCGAGCCGGCGATCAGCGCCATCGAGCCGCCGCCGGTGCGGGCCAGGAAGCTGACGTTCCGGGTGGGCGGCAGGGCGGCGGCTTCCGGTGCGGTGACCTTGGGCGCGCCGCCGTCGTTCGAGTAGGTGTAGTTGTCGGCCGCGACCGTCTCGATACTCGGGGAGGCGTCGTCCGGGACGGTGGTGCTCTCGCTCGGGCCCGGTGGCGAACTGCCGGAAGCCGGACTGCCGGGCTTGGCACTACTGGGCCGTGCGCTGCTCGGGGCCGGGCTGGCGGCCATGGTCTGCCTGGCGGTCATGGTGCGGCCGGCCGTCACGGTCGGACTGGCGGTCACGGTCGGGCTGGCGGTCATGGTGTGCCTGGCGGTCGGTGACGGGCTGGCGGTCGGTGTCTGCCTGGCGGTCGGTGACGGGGTCGCGGTCGGGGTCCCGGTCGCTCCGGGGAACGACGCGTCGACGGCCACCCCGTCGCGGGTTCGCAGCCGCACCGGGTTCGGCGACCGGATCAGCCGGTCGCACCCCAGATTGCCGTACGACCCGCTCAGTCGCTGCGCGAGGAAGGTGAACAGGTTGGTCGCCACCCCCGGATCCGGCGACGCGATCTTCTGGGTGAAGCGGCGGTCGGCGCGCAACCGGCTCGGCGCCAGATCAACCAATTGCTGACAGTACGGCGCTGCCAGCCCCCGAGTCCCGGAGACGGTGCCCATGCCGACACCCTGCCGGTACAGGTTCAGCTTCGTCCGGTCGAAGCGCCCGTCCACCTCGGCCATCGGATCGTTCGGCGGCACCAGCGCGACCGGATCCCGCTGGTTCGCGGCCGCCTGCAACTCGTTGAGCGCCAGCGAGGTGGTGAGCGTGCCGTTGTCGGCCAGGTCCGGCGCCTGGAACGGCGTGCAGCCCAGTGCCTGGTCCACGAAGTGCACCAGCAGCAGGTTGTCACTGCCGTTGACCAGTACCGGCGCATGCCGCAGCCGCGCCCGGTTGGCCGCGGTGTCCTGCGCGACATGGCTGCCACGGATCAGGTACGCGCTCGTCACGTTGTCGCTCTGGTCCTGGTCCACGACGGTGAAGTCACGCGTCGTCGGGCACGGCTTCCCGTCCCGGCCGGTGCCGAGCGGCGGTACCTTCAGTTTGCCGGCCCGGATCGCCGTGTGCGCCGCGCTGAAGAACGCCGGCGCATTGCAGTACGCGAACTGGGAGAACAGCGAGCCGTCCACCCCGTTCACGCAGGCGCCGCCGCGCAGACTGCCGTGCGAGTCCACCAGTCTCAGGTTCTCCCCGTTGAACCCGAACCAGATCCCCACCACCGCGTTCTTCGGCAGCACCGGCACCACCGGGTCCAGCACCGGCCGCGTCCCCTTGTCGATCACCAACGGGTTGTAGACGCTGACCTTGCCGGTCGCCGGATCCACCACGCTGGCTTGCACAAACGCGGCCTGGGCAGGATTCGCCTCATGGCACGCGCCGCGCCGGCGCCCGGTCCCCGACAGCTCGTACGGCGTCGCCAGCCCCGCAGCGCTGAGCGGATCCGCCGGCACGAGCAGCGAACAGTTCGTATTCGGCTCGGCCCCGGCATCGTTCTGCCCCGCATAGGACATCCCGGTTCCCACCCCGAGCGCCCCGAGCACCACGATCCCCGCGCCGATCACCGCGATCCGCCGATTGCTCCACCTTCCGAATCGGCGGTAGATGCGTTCCCGCAAGCGGAACACCCCCTGCTGTTTTCCCACGTGGACGGCCATGTCCAGCAGCGGGTACGAGGTGTTCCGGCGCCCGGTTCAACCATCGCCGTGCCAGTAAATCCGATCGCGTCGCGATCCCGCCTCGGTCAACCGCCATCACCCACCGTGACCTGCAACGGCATCGTCCAGCGCGGATGTCCCCTGGTGTGCCAAATCCACGGTCGCCCGTGATCGAAGGTGGCCGATGGCCAGCGCCGGCCCGTTCCGTCCCGAAAACAGAGCGCTACACGACTATTGCGGGGAGAATCACCAATAATTCCGCGCCGGTATCGCCGGTATCGCCGGTTCGCTCGACGGCGCTCCGGACAGCCGGCACGCTGCGGTTCCAGTGGCCCGGCGAAGGGCAGGTACACAGCAGATGGGCTGGCTGTCGAAGCGTCGGCTCGCAAGGCGCCTCCTGGTCAACGCGATCACCATCGCGGTGTTGGTGGCCGTCGCCGTATTGGGCTACTCGGTGTCCCACCGCCAGGAGACCATGGCCGGGCAGGCACGACAGGCGCAGCGGTTGGCCGAGTCCGCGCAGCAGGTGAAATTCCGGGCGGCCGACTTCAACGGCTGGCAGACGGCATACGCATTGGACATCATCCGCGCCGTACCGGGGGCCACCGCCGACACCTCACCCAGCCGTGCGAAGTTCCTCGACGCGGCGGCGAAATTCGACAGCGAACTGGACGCCCTGGAAGTGCTGTCGGCGTCGTCCCCGTCCGCACGGACCGTCGACGCCGTCAGGGAGGCGTTCGAAGCCTTCATGACCCTCGACCGGACCGTCGTGACGCTGTACCGCAGCGGCAAGCCGGCCGACCGCAGGGCCGCCTCCGAACTCGTCCTCGGCCGGGAGATCCAGCTCTACGGGCAGATCGCCAACGGTTGTGACGCCACCGCCGCGCTGTCGGCCGCGGCGGCGGACACCAGCATCGGCCGTCTCGACGCGGTGGGAGCCGCCATCCGGCGCTACATCCTGATCCTGAGCATCGTCGCCGCCGCCCTGACGGTGCTCGGCGCGATCCTCGCCGAAGCGCGACAACGGGCGATCGCGCAGCAGGCCAAAGAGGCTCAGCGAATGGCGAGCCTGGGACGTCTGGCCGGGGGGATAACCCACGACTTCAACAATGTCCTCGCCATCATCCTGAACTACACCGACTTCGTCGCCGAACACGCTTCCCCGGAGGCACTCGACGATCTCGCGCAGATCCGCAAGGCGGCGAAACGGGCGGCCGGGCTCACCGCGCAACTGCTCTGCTTCATCCGGCACGAGGCCATCCAGCCGCAGATATTCGACATCAACGCCGCGATCAACGAAGCGCACGCCATGCTGGCCCGCACTCTCGGCGAACACATCGAGCTGGTGGTGATGCCCTCGCCCGAGCCGCTGAAGATCTGCGCGGACACCGGCCAGATCCAACAGATTCTGGTCAACCTCGCCGTCAACGCCCGTGACGCGATGCCCGACGGTGGCACCTTGGTGATCGCGGCCAGCGCCGTCGACCTCGAGGAGAACCAGGCGAACGTGCACCCGCCGGTGGCGGCCGGACGTTACCTCCAGCTTCTCGTCACCGACACCGGTACCGGGATGTCTCCGGAAACGGTGGCCCGCATCTTCGAGCCCTTCTTCACCACCAAGCCGAAAGGCCACGGCACGGGACTCGGTCTCGCCACCGTCCTGGACATCGTCATCACGGCCGGCGGCAGCATCGACGTCTGCTCCAAGCTGGGTATCGGCACGACCTTCCGGCTGTACTTCCCCGCCGTCGACGTGCCGTACGGTCAGGAATCGGAAGGTCGCAACGATGTGGCACCGCCGCGTGGCCACGGCCAGAGCATCCTGATCGTCGAGGACGAACCGGCCCTCGGCACCAGCGTCGCTCGCATCCTCGCCGCCGGCGGATACCAGGTCCGGTCCGCCGTGAGTGGTCCCGACGCCCTGGCCGCATACGCGGACGACGGCTGCGATCTGCTGATCGCCGACGTCGTCATGCCCGACATGTCCGGCTCCCGCCTCGCCGAGATCCTGCACCGCACCGACCCTCGCCTGCCCGTGCTCTACATATCCGGTTACATCGACGGCAACCTCGGCGCCAACCGTCTGTGCACACCCGAGACCAGGGTGATCGAAAAACCGTTCACCGCCGACCAGCTGCTCGTCGCGGTCGGCGACGCCCTTTCCCCGGCTCCCGACGAGAACGGCATCACCGGCGGTCGGCCACGGCCGGTCTGATCCGTGCTCCCGCAACCCGTCAGCAGGCAGGAGGACGGGCGGCGCCGAACGACTCGGTGAGCACGGTTGCATGCCGCACCTTCACGGTGCCGAAGGCGAGCCTCTATCTGGTCCGGGTGTCCGTGTACGACCTCGACGCCAGGAGGTCTGCCGGTGGGGCTACTACTACAGCCGCGGCCCCGGGTGGATCTTCGGCCCCGACGGCCTTCCGGTGCAGGCCTGTTCCTCCAGCACGGCGGTGCGCGATCCGCTCTGCGATCTGCAGCCCGGCACCTACTGTTCACGCGCTTCGAACCGTGCCGGTCGAACGGGGCGTACGGTTTTCCGCGGGATGACGATCGTCAACGTGAGTCGGGCACTGGGGGCGAGCGCAGGTATGCGGGCCGGATGAGGAGCTCCCCGTCAGCCGGTCCCGGTATGGGGGGCCGGCGGCAACTCATCGCGCAAGTTCGCCGCAGCCACCTCGATGCCGTTGATCGGCGTCCTTGTCACGCTGGTCGGCTACCTGATCACGAACATCGGCCGTCCTGTCCCTGGCGTCCGCTACGGCGTCGCGCCGGTCGCCATCAGCCACGCGTCGATCTGCGGCGTCGTCGCGTTGATCGCTTCGCCGGTCGCGCCTGCCAGCCGCGGAATCCCGGCAGTCCAGAAGGAACTCCCGCCGGTCCGCTGCCTGGTCCCGCTCATCAGCGCGCGCCAGCCGGCCCTGCAGGTCGATCTCCCGCTGGTCGGCCTCGGCATCACGCCGATCCGCCGCCTCCTCCCGACCAGCGAGGTAGCGCTCGCGTTCATCCAGAAGCCGCCGCCGTTGCGAGTCGGCCGATCCGGCGTTCATCACCTCACCATGGAGCGGGATGGCCTGAACTCCACTGGGCACCGCTTGGCCGGCATGTGGACCGGGTGGGCTGTCGGATTTCGAGACCGGATTTGAGTGCAGGGTGGGGAGTGCATGGGTTGACCAGCGTCGCTGCGGGTTATTGAGGTGATGGGTTGCCAGCGGGCGATCGGTGAAGCGTGTCGGTTCCGGAGGCTGTGGTGGATCTGCAGTTGTCAGCGCGGACAAGTGGGGCGTGCACCGTGGTCAAGGTCGGCGGCGAAGTCGATACGGACACTGTGCCGCAGCTGGAGGCCTTTCTTCAGCAGGTCGCGGACGGTGGCGGCGTCCGGGTGGTGCTCGACTTGGCCGACGTGTCGTTCCTGGATTCCAGCGGTCTGGGCGCTCTCATCGTGTGGTTCAAGGAGTTGCAGAGCAGAGGCGGTCGGTTGTGCGTCGCCGCGGTGCAGGACCTCGTCGCTTACGTGCTGCGGGTGGCGGCGGTGGATCAGGTGGTGAATGTTTACGACACGGTGGAGGCCGCCGAGGCGGGCATGCCGCCGTCGACGGCGTGAGTGCCGAGGTGAGCTCAGCGGCCGTCGACTGAGGTGGCGGCGGACACGTCGGCCCCACCACCGCGCCCCGGCACACCCGCAAACCAATCAAGCAGAGGACCGCGAAGAACCGGCCCGCCGGCCGCGACGAAAAACAAAAACCCTCCGGCGACTCCGCCACCAGATCGCGGAAAAATCGCAGGTCACGCGGTCACCGCCGCCCTATTCGACGCGGAAACGGTGACACCCAACCGGCACCCACCGTCCGCAGGGCCGAAAAAGCCAAGGGCCCGAACCGCGTTTCCGCAGCTCAGGCCCTTGATGATGAAGTGCGCCCGAAGGGACTCGAACCCCTAACCTTCTGATCCGTAGTCAGACGCCTAGTAGTCATTAGCACACTCTGCAACTTGTCTGGTACGCCGCCATTCCGAAAGCGTTGCGCCAGCTCAGAGGCTGTTCACGTTTCAGCAGGCCGCAGCCGAGTACATGATTCCAGCACCATCGGAGCCGATGACCCCGACACGGCCGTGCTGATTTAGTCGCGGTAGTACTGGAACGGTCGCCGACATCCGATCACCCACGGATCACCCAGCACCGTCGTCACCCTGCGTAAATTCGCCGGCCGTAGCGCCGGTCCAGGCACCCCATTGCGCAGGTCGGGCACTCTGACCCGAGCAACAGCGGTCCGCTTCAATGCGCCCTCGGATCACCACGGCCGCCGTCACCCGCCCCAGCTCAGCCAAGATGCGAGAGCATCTGATCCATAGGCGGCCTCCTGAATACCGACCGCATTTCATTGGGCCTGCCCCGTTTTGACGGACATCCAAGATCAGGGGACCTGGGGTCTCCGGGAGGTTGTCCAGCATCATGGAGAGCGTGGGAAAGAAGCGGTCGAGGCCGCGGCGGGCGTTCACGCCCGAGTTCAAAGCCGAGATCGTGGAGTTGTGTCAGCGTGGTGACCGCACGGTGGGGCAGGTCGCGAGGGATTTCGACCTGACCGAGACGGCGGTGCGAGCGTGGGTCAAGTAGGCCGACCTCGACGCCGGCACCCGATCGGACGGGCTTACCTCCGACGAACGCGGCGAGCTGGCCCGGCTGCGAGCGGAGAACCGCCGGTTGCCGCAGGACGTCGACATCCTCAAACGGACGGCCTTTTTTCGCGCGGGAGACCCGGTGAACGTGTATCCGTTCATCGAGGCGGAGCAGACCGGCAAGCACAACGTCAAGCGTGCGTGTGAGCTGCTCAAGGTCTCCCGGTCCGCCTACTACCAGCACGCCCGCGGTGAACAGTCCACCCGGGACCGCGTCGACGCCCGGCTGACCGAGCAGATCATCGCGGTGCACGCGGCCTCCAACGGCACCTACGGGGTGCCGCGCATCCACGCTAAGCTGGCCGCGGCCGGGCTGCGACATGGCCGTAAACGCGTCGCCCGCCGGATGAGGGCTGCCGGGATCGCCGGCAAGTGCCCGCGCCGGTGGAAGACCACCACGGTCGCGGATCCGCACGCCGGCGCCCGCCCGGACCTGGTCGACCGCAACTTCCGGGTGGACGCCACCGCGGTCGATACCCGCTGGTGCGGCGACATCACCTACATCAACACGTGGGAGGGCTGGCTCTACCTGGCCACCGTCATCGACCTCGCGTCGCGCCGGGTGGTTGGCTAGGTGTACTGACCCGAGAGGTTGGGGACGCGGCTGGCGGGTGGTAGGCCGTTGAGTGCGGTGTGTCCGCGGTGGTGATTGTAGGTGTGTAGCCAGGCGGGCAGGGCTTCGCGGCGTTCGGTTTCGGTGCGGTAGGCCCGGGCGTAGGCCCATTCGTCGAGCATGGTGCGGTTGAAGCGTTCGACTTTTCCGTTGGTCTGGGGCCGGTAGGGGCGGGTGCGTTTGTGGGTGATGCCGGCGGCGGCGAGTGCGTCATGCCATAGGTGGGAGCGGTAGCAGGAGCCGTTGTCGGTCAGTACCCGTTTGACGGTGATGCCCCGGCTGGTGAACCAGGCGTGGGCGCGTTGCCAGAAGGCTGTGGCTGTCTCGCGGGTCTCGTCGGGCAGGATTTCGGTGTAGGCCAGCCGGGAGTGGTCGTCAACAGCGTTGTGCAGGTAGTGGTAGCCGAGGTTGGGCCGGCCGTGGTGGGTGCGGGGACGGGCCGGGTCCCGGTGGGCCGAGCTGTGGCGGTTGCCGTCGGCCCGGCCGTGGACGCGGTGGCCGCCGCCGTCGGGGATGTTGCCGAGTTTCTTGATGTCGACATGGACCAGATCGCCTGGTGTGTCGTGTTCGTAGCGGCGGATCGGCCGGCTGGTGGCCCGGTCCAGGTGGGTGAGCCTGGCGAGCCGGTAGCGGGTCAGGACCCGGTGCACGGTGGCCGGGTTCAGGCTCAGGAAGTAGGCGATCCGGGCGGGTCCCCAACGGCGCAGGATGCGGACCTTGATGATTCGCCGCTCAGTGCGGGTCGGAGTCTGTGACGGGCTGTGGTGTGGTCGCGAGGAACGGTCGGTCATACCCGCCGGCCCGTCGGTGCGGTAGCGGTCGGCCCACCGTTTCGCTGTGGTCGTGCTGACCTGGAAACGTTCGGCGGCTCGCCGTAGCGGCCATCGGTCATCGACCACGCAGCGCGCCAGGCGCAGCCTGCCGGTCTCGGACAAGGGTGCATTACGGTGGGGCATGAGGGCCTCCGCAGGTTCGGGGTAGGACGTCGCAATCCACACCGAACCCGAAGGCCCTCACCTATTTCAAGATCTCCCCGTCACCAACGTCCGTGGTCAGTACAGCTAGGCCGTCGCCGACCATCCCAAGACCGACCTGGTCGACGCCGCCCTGACCGATGCCCTGGCCCGGCGCCGTCCCGCCGACGGCCTGGTCTTTCATTCCGATCGCGGCTGTCAATATACGAGTGCTCAGCACGCCCGCCTCGCGCAGCGGCACGGCGTGCGGCTGTCCGTGGGCCGGCGCGGGCAGTGCTGGGACAACGCGGTCGCCGAGTCGTTCTTCGCCACGATCAAGACAGAACTCATCCACCGCCAGACCTGGCCGACCCGCAAGGCAGCCCACCAGGCAATATTCGAGTATGTCGAAGGGTGGTACAACACCCGGCGTCGGCATTCCAGTCTCGGCTACCGCAGCCCTGCCGCCTACGAGGGCGGTGCCGCCATCAGCCTGCTACCCGCCCTCAAGGTAGCCTGAAGATCAACTCATCGACCCTGTCCGTCGAAACGGGTCAAGCCCAACGTCGATCTGGTCGTCACCGTGAACACTCTGTGTCAGCCGAACTGCGTGTGAACCCTTTCGCCGGCTACGGCTGCCCGGCACGCTGCTCTACACGCCGCGCAAGCCGCGTAAACGCTCCGGCGGGAGGCGCCTACGTCGCTGCTTGTCTGGAGTTGGCGGAGTTACCCGTGCTGGTCGACCTGTACCTGGGGCCGGCAACAACCGCCGTCCTGCCCAGTCGGCGGGAGGGCGCTCGTTCAGTGCGGCGAGCTCTCCCGCGCCGTTGGGCCTGACCGAGGCCTTGGCCGGGCATCCCGCCGACGACCCCGCCGGCGCCGACCCGAATGATCCGGTCAATGATCTCTATCTGATCCGGCTCGCGGCGAAGTATCACGCCGCCGCTGATCACCCCCGCTTCGCTGATATCTGCCGCAGACCGAGGGTTCCTGCCGATCTCGGTACGTCCGCTCTGCGGCGGACCCTTGCCGCGTGTGTACCGCTCGCGGGCACTACCGCGATGCGGTCAACGGGTGGTACTTACCTGCCATCGCCGTAGCCTCCCGGCCCCAAGGGTGCCGGGTGACGATGACATCCGGAACCGCCGGACGGTTGCTCTGCCGCCGCCTCGAGGGAAAAGGATCATGAACCGTTTGCGGCTGGTTAGGGTTTCTTGATACGAGAGAGGCGTCGAGGCCGCCAGCTCCGGCTTCCGATTTGGTGGTTTCGGGCCTGATAGTGCTGATCTTGCCCTGACCTCGCCGGATTTCGGTTGTCGGCGTTCGCTATGTTCATCCTGCTCAATACGGGGGAGGTAGCGTGGGCGACGAACTGCATGTCGAGCCCGCCGTGCTGCATTCTGCGCGGCAGGTGTGCGAGGACTTGGGAGTCGCGTGGAGACGCGATGAACACGGTGTCGAACCGGTTACCGAGGACGCCGCCGCCGGGTTGCCGGGCTGGATGACCGGGCGGGCGCTGGGAGATTTCGTCTGGTACTGGCAGGACGACGTCAAGAAGCTCACCGGCTATCTCGAAACCTTCGGCGACGCGCTGCAGCGGGCTGCGCTGACGTATGAGCACACCGATCACGCCAGTGCCGATCTGTTCGACATCCGGGGGCGCTGACCGGTGGTGACCTTCGCGGATCTACGCGACGCGCGCGTTGACCGGCTTACGGTCGCGGCCGACGTCTGGCGTCAGCTCGCCGGCAAGTGCAGCAAGCTTGAAGACCGGACTGAGCTGGAGTTGTCCAAGCCGTTGCAGAACGGGGCCTGGGAAGGTGCGGCGGCTACCGAAGCGCTGCGCCGGATGACGTCCCTGGAAGACGAGTTCAGCCTGTACCGGATGAAGGCCCGCAGCATCGGCATGCTGTTGGAGCGAATCGCCACGGACTTCCAGGGCTTGCAGCAGCGGCTCCAGTCCGCGATCGACGCGGCTACCTCGCTCGGGTTGACGGTGACCGCGGACGGTCGCGTCCAGGCCGATGAGGTGCCGCAATCCGCCCTGTCGGATCCTGGCGCGCTGGAGGTCAACCGGCTCGCGAACCAGAACGCCGACGTCTACACCGAGGTGATCGCCTCGATCCTCAAAGATGCCGACCACATCGATCTCACCTACGCCGGCATGCTGCGCGACTTCGGCCCCGACGTCCAAGGCCCGAACGAGTTCAGCTGGCAGCACACCACCGACGCCGCTCGCGAGCTTGCCGGGCTGAACGGACTCACGGCAGACGACATTACCGCCGCCGGCACCAACCCGGCCCAGGCCGCCGCCTGGTGGCACGGCCTCACCGCCGACCAGCGCGAACTGCTATCGATGGCCTACCCCGCCGAGGTCGGCCGCCTCAACGGTCTGCCGGCAACCGACCGCGACACCGCGAACCGGCTAGCCCTGCACGAACTGATCGGGCAAGGCGTGAACCAGCGCGTCGACCCGAACGATCCACAGCATCAACGCCTGGTCAACCTGATGAACCGGCTCGACGCCGCCGACTACCAGACCGGCAAACCGCTCTACCTGCTGTCCATCGACAACCAGGGCACCGGACGGGCCGCCGTGGCCATCGGTAACCCCGACACCGCCCGGCACACCGCCATGCTCATTCCTGGAGTGACCAACAACCTCGACGGGATGGTTGACCAGATCGGCCGGGCCGACCACATCCGCGACGCAGCCGAACTGCTCGGCGCGAGCGACGTCTCGGTCATCGCCTGGCTCCAGTACGACCCTCCGCAGCTCGACGACTCCATCGTCACCGCAGCCGGCTCCGACCGGGCGCAGGAGGGCGCCACCAACCTGCTCGCGTTCACCGACGGGCTAAGGGTGAGCCACGATGCCGGGCCGGTGCACATGACCGCGATCGGCCACTCCTACGGATCGGTGGTAGTCGGCGACGCCACCAGTGGCGGCCACCGGCTGGCCGTGGATGACGTTGTCGTGGTGGGCAGCCCGGGCATGGACGTGCACCGGGCCTCGGACCTGAGCGTCGGCGCAGACCACGTCTGGGCCGGCGCCGCCCCCGACGATATGGTTGCCAGCCCGGACACCGCCATTCCGTTGGAGACCGGCATTCCGGTGGCCGGCGACGGCGTACAGGCCGCGATCAGGTTGAAGCACGGCGTCGAACCGCATCTGCCAGAATTCGGTGCGCGGGTCTTCATGACCGATACACCAGGGCACACCTCCTACTGGCAGGCCGGGTCACAGAGCCTCAAGAGCCAGGCATCCGTCGTCGTCGGCGACTACGGCAACCTGATCCCTCGATACGGAAAGTTTCCCTCATGACACGCCGCCTGATCCTGGCCCCGCTGCTGCTCGGTGCGGTGGTCGCGCTGACCGCCTGCGACAGCGGTCCCGCCAATCCCGCAGACACACCCGCCGCCAAAAAGGATCAGCAGATGCAGGTCATGAAACGCACCGACGCCGAGAACCTGGCCAAGAAGCTCGCCGAGCAGGTCGCATCCCTCGTCGGGAAACCGCTCACCGGATGGCGAACGAGTTCGGCTGCCTGTGAGAACACCGACGGGGTCGTCGCCTCCGACGGCCGATGGGACCTCAGCACGGGCGGCAACGTCGAAGTGGCCCGGGACGACCAGGTCGCCACCCTCAACAAGATCCGTGACGACTGGACCAGCCGCGGATACCAGATCACCGAGTTCCACCTGCTGCCCGACGGCGACACCGGTGGAAGCACCTCGGCATTGGTACCGGAATCCGGCCTGACGATCTCCGTCCAATCAACCGTGCCGCGGACCGGCATAGCGATCATCGTGGTCACACCCTGCTACAAGCCCGCCGGCAACGAAAACCCCGCCAGAGGCTACTGACCACAGCTCCCACGGAGTACCGAGAGCCGCGAAGGTCGTGACGGTAGGCGCTCGCATGCCCCGAGCGGGTGACCACCGCGCATCGCGTTTCAGGACACATGGCACCTTGCTCACTCTCAGCCACCTGTTCGTCCTGCTCGCTCAGCCGGAACCTCGGCAGCCCAGTCAGCTGTCTCGACGTCGTCGCCGGCCGGCGATGGTGTCTCACCCAGCGCGAGAGACGGCCGACCAAACCCTTACGGCGTCGGACGGACTGGAGTCCCTGCTGCACCGCTACAAAGACTTCGGCCCGGATCACCGATGGCTGGCCGCGCCCCTGGCCGCGCTGACCCGTGACCTTCTCGTGCGGCACCTGCGCTGCCTCGAAACCCGCTTCGGCCCCTTCGACTTCCAGACCCACGTCCCGAGCTGGGGGCGACCGCCCCTTCGACCCGCTCCCGACCGCCGCCAGCCTCATCAGCGACTGGCCCGTGCCATGGATCTTCAACCTGATGTCGAAGACCAAGGGAGGAGCGTCCGGCGCGTGGTGTCGTGGATTCCTCCTATTTTCGGTTTAACGCCTCCACCCGGCTGCCGGGATCGGCGATCCTGCTGGTCGACGACACCTGGACCTCGGGGGCCTCCCTGGTGAGTACCGCGAAGGTGCTGCGCCCACGGCGCCGCCCGCATCGTAGGCCTCACGGTCGGCCGGCAGCTCACCGAGGGCTTCGGCAGCTCCGCGACGATCCCACGGTCCTACCGAAGCCCTGGCCGAGGTTGGACTGCCGGTCTCGCTGGCCGCCGGGGCGACGAGTACACAGTTCGACCAGCAGATCAAGCAGTCGCATCATCAGGCGTTTGACGAGGTCGGGCTCGACGTCGGCACGCCCGTGATACGGATCAAGGGCACGGCTCTGTTCGGGCCGGTCATTACGCCGGCGCCGCGCGGCGAGGCTGCGGGCCGGCTGTGGGACGGCCTGGTGCTGATCGCCGGCACGGACGGGTTCTTCGAGCTCAAACAAACGCGGACCCGTAAAGCGTCGTTCGAGTGACCCGGCCGGACCGTTCCCAGAACATCGCTGCCGGCATATGCAGCAAGCAGCGCGGTCACCTGGTGCACTTCGCCCGGGCCCGCCGGACCACACCGCCAGGCTACCCCGCGGTCGTGGATCCAGCGGTTACCGACGGCTGCTCCCGGTCAGCCGATGCGGACCGAGGGGTTGCAGGCTCGCCAGACGCGGGAGCCGACCAGGCGTTCGGCCTCGTCCAGCCGGTACCAGGCCGCGCTCGTCACTTCCGACTCCTGGAGGCTGCCCACGTCGCCTGTGGTGGTGAAGGCATATCCCAGGTCGAGGTGGAAATGTTCCGGCTCGTCCTTCTGCGGTCGAGCGGGGACCCGACCGAACTCCACATACACGGGCGTCGCGGACGCGGTAGTGACCGTGGTCGGATCGATACCGGTCTCCTCTGCCAGCTCGCGTACTGCCGCACCCATCAGAGTCGTGTCACTCGGCTCCAGATGGCCACCCGGCTGCAGCGGAATCCCGTACGCGCGATGCCCGACCAGCAAGATTTCCTCGCCGCCGCGGGTCAGCAACGCGCCGACGGTCACGTGCAAGTCGAAATTGCGTCGAGAGGCAAAGTTGCTGCCCCGGGCGAGGAGCTCGATCGGCTCGGCCAGCAACGCCTTCTCCGCGGGATACCGGTCGAGGTAGGCGGCAACGGCGGCGGCGATCTCCGCATCAGCGATCGGCATGCAACGCCTCCCAGGCAGTCGGATCCATTGCGTCCTCCGGCGCAGCGCATTCATACCGCTCCGCGGCTTCACCGGCCGACGACGACAGGACCCGGCGAACCTACCGCGTACGTCAAGCCCGGACACGCACAACGGCTGTGTGTCTCGTCGCGGATGCCCGCCCGTGCCGTTGCGGTTCACGACCGCGTTACTGCCAGCCGCCACGATGGCCGGGAACCGCTTCGTCATGCCCGCCGTCCCGCCTTGCGCGTACGCCCCTTTTTCGTGGTGAGAGCGATGTCGCCGTTTCGGCTGGCCACAGCGATGAGGTCATGGGGTGTGAACGCTCAGCGACACGCAGCGGTCGTCCATCTGTGCGATTGCCGTACCCGCATCGGCGGACTTCGTCGTGTCCGAGACAGCCCCCCGGCAGGGCGGGCGAGTACCGATATGGGGAGGGCTCCACAACTTGTCGTCGTTCCTCCGGGCTCTGACAACGCAGACCATCCGGCAGGAGGGACACGAACAGGTGAGTGCCGTTGCCGTAGAGACGGGCACCTGGAGGAGCGTCCCGTCGCAGACGCTGAAACGCCGGGGAGGCGTTCCCTGGAATTCGACACTGGTGGCGGGAAACCGGTCTGCAGGCGGGTAGGCCTCCGGCGCCTGCGGGGCCGGGTTCACCGTGCACAGTCGGCTGGTGTCCGGCTATGGCCGGCTTTTCTGCGGACAACCGCCCGAACGCAGCGGTTCGCGGCAGCGCGCCAAGGTGCGAACTAGCTCATCGGCGAGTGAAAGGACCAGACGTGGACATCCACACCACCAAATCCGATGGAGCACGGCTACCTGAACAGCCATCCCCGGATGGCACGAATCAGGAGGCTTCCACCCCGCTGGAGCCGGTGCTGCCGGAGCTACGGAACGCGTGGTAGGAACACGGGATGCGCCGACGGGCGGCGGCGGGCGTGCTGGGGGTATTCGCGCAGCCACGCCGAGCTCTTCGCCCTCCAGTCTGCGGGCTACACAAGTGGACAGGAAACCGTCCCGGCCGATCCCGTGAACGAATGCGCGGAGCGTCCGTGAGCGCCTCAGTAAGCCCTCCGCCGGATCCTGTAGCCGGGACCGCCGTTCGCTTCGACCGAGCCGCACCCTGATCGACACATGATCTATCCGCCGACTGCGCTACCCCGCGCCTGCTGTTCTGCTACAGCGGGCATTCCCCGGTCGCACCGACCGCGCCGCCGCAGATCCGTCGCCTCAACCGTGCAACCTGGGAGGATCCGTGACCGACCTCAATGAGGCTTTCGGTGCCGTGCCCGTTCTCGCCTATACCGATCACGAGCGCTACGGTCCGACCGTCCACCGCTCCGTGCCTGAGTGGATTCAGCGTGAAGTGACATCCCTACGGGTGCAGGCCGGGCATCGCGTTCTGGAAATCGGCACCGGCTCCGGTTACAGCGGCGCCCTGCTCGCCCGCCTGTGCGGACCACGCGGGCGAGTCACGAGCATCGACATCAGCGAGGAACTCATCAACCGGGCGCGCGCGATCCACGCCGAACGCGGAGTCACCGAGATCGACTGTCACGTCGCCGACGGCCTGGCCGGCTTCCCCACCGCCGCGCCGTTCGATCGGGCGGTCGGGTGGTGCACTCCGCCGCGGCTTCCCCGGACCTGGGTCGAGCAGATCACGGATGGCGGCCGGATCGTCGCCTCCCTGCCAATCGCACCGCTACCGTCCACCGCCTTGATCACCACCATCACTGTCGACGCCGGGCAGCCCCGAGTGCAGGCCGTCGTCGGTGGGGTTTACGCCCAGAGCACCCCGGCGCCCGTGGACGACGCCGTGACCGTGCCCGGCCGGTGGGTCGACTACTGCGACCGCCAACCGGATCCGTCCTGGATAGCCATCAGCTGGCGCACCGAAGATCCACACAACAGCGGCGCCCGCGCGGCCCTCGACCGGCTCCTCAACCCCGGGCACACCGAAACCTACGGCGACATGGAGGCCGACTGGCGGTCCTGGAGCGCCCACACCGCCGCCCCGCCCGACCCCGGTCTGAGCATGGTGTCGCTGCGCAATCAGATCCGCGGGATCGGCCACACCACCGCCACATCCGCAGCCGTGATCCTGACCGACGGCACGATCATCGCCGACACACCGGACTCGGCGTCGCTAACGGTCCTACGCGAGTGGCTAATCCTCTGGCAGCAGGCCGGCCGCCCCACCGCCGACAGCTTCATTCCCCGACTGGTCCCCAACACGAGCATCGACTGCCCCGGCGGGGACCTACAGCTAGCCGTGCCCGCTGACGCGGTGCCAGCGTCGCGGGCCGCTATCCCGCAGCCGCGCGCCGGCCGGGTGGAGCCGGCATGACGCCGGAAGACCTCGCCGACGCCGCGATCGACCTGGCCGAGGAAGGCATGCCGCGCCGCGAGATGCCGATCGCAGCGGTCTTCGAGATGGGCGGGGAGATCATCGCCTCGCCTACACCAGAACCATAACGGTGAGGTTCGATCGCAGGGGCTACATTCGCGGCGCCAAAGTGCAGCTCACGACCGGTGGGATAGCGCGAATCGACAGTCCTTCGACACGCGATCACCACAGGATCACCACGGTCCCACCGGGCGGGATTTTGAAAGCAGAAAATGGGAAACAAAAAGGCCGTGACCCTTGTTTCCGCAGGTCACGGCCTTGATTACTTGTGCGCCCGAAGGGACTCGAACCCCTAACCTTCTGGTCCGTAGACAGCGCCCTAATCAGAAGAGCTCAGGCGCGTGAACATCAAGCTCACCACTGCCCGCTTTGCCAGAATCATACCTATCTTCGATCGTCCAACGCGGCGTCTCATATAGCAAGATAGATGATGCCTATACCGCTCCGCAGCGGGCTCGACGCCGATTCGTCGACAGTGCGCATGACCGCGTTTCCCCGCCTGCCCTCAGTCAACGCTAATCTCAAAGTAGTCATGCATTCCTATGGTCTGTTACCAAAGCGATCCAGCACAGCTGACGGTGTAGTAGCGCGTCGGGCGCGGCCGAGCCATCGCCGCCAGAGTGCAGCAGATCGGTGTTCATCTGTGAGGCTTCTGGTTGAGGTGCCGTCATTGCTGTCTCGCCCGTCATTGCCGGTCTGCGTTGTCGGATATCACGAGGTGCTGTTGCGCTTGAGTGGGGCTGAACCGGCGCGATTTCGGCCGGTGCGTTCAGGGAACTCCAGTGTCTGCGGGCACGGTTCACCGTTGATCATTCGACCGCAGTACCAGAGCCAACGCCGATCGGGTGACCTCCCAGCTTCTTTGGCCTCGGTCATGGTGTTGCCGCAGGTCTCGCAGCGTGGTGGGTTACGCATCTGGTCGGCCAGCTCGAAGGACAGGATCTGGCGGGCGAAGCGGGCGCTGTCGATCTGGATCATCACTTCGTGGCGGCCCTCTGCCGGTCGACGAGGGTGCGAGAGGATGTTCATGCTGCCGACGAAAGTCCACCGCAGGTCCACGACGACAATCTTCTGGTGCATCTTGTGCACCAGAACGACGTGGGGCAGCCGCGCTCGTAGGGCGTTCAGTGTTGCCCGCACCTCAGCGTTGATCTCTTTCTCTGGCAAGGCCATGACGCGGACCTCGACCTGACGGGCGTGAGCGGCGACCAGGCTGTCCTGCAGACCCAAGGAGTGCTTACCGACCCAGGGGCTCCACATCCATACCGACGACGCGGCGCTGTCGACGCGCTGCTGGACCTCGGCGATGATCTGCTTCTCGTCGTACATTCCGACAAGCCGTATGTACGGCTGGAGCGCACTCCACAGGTCGTGGTGAACGGTTTCCTCGACTGGCGCGTTGGCCTCGTCGATGCCGAGGAGGTCGCTGGCGAGGACACGTTGGATCGTGCCGGCGTCAATCATGTGTCGCAGTGCGCCAAGAGGGCCGCTGCCGCGGCGCCTTATTGCTGCGCCGTCACCGATGAGGTAGAGGCGTTGCCGGGCCCGGGTCGTCGCGACGTTGAACAACCGTAGCCCTTGCAACTTCCATGCGTCGGAGCCGTGAGCGCCTTTGGCGACCCATCCCCTGCCGTCCTCGACCATGTCGAACACGACGATGTCGCACTCGCGGCCTTGAAAGGTGTGTGCTGTGCCGACTTCGATCGCTGGGCCGCACGCGGATTCGGCGAGCAGTTCCTGCGTCGTTTCTGCCTGCTCCTTGTAAGGGGTCACGATGCCGACGGACCCATCACGGGGGTGGTGGTACTCGGCGAGAGCTCGAGCGATGAGCGCGCCGATCGGCCACGTCCCGGCGACAGCGTCGGGACGCGCCCGGCGTATGCCACTGAGGGCTTTGCCGAGGCCGTCGGTGTCGACGAGCACGATCTCGCAGGTCTTCGGGTTTTTGGCGGTCAGCAGTCCGCCGTAGGCCACCCGGTTGGCTAGCTCGGTCAGTTCCCATCCGAAGCGCCATTGCTCGGTCAGAACCACGCAGCCGGGTTGCTGGGACGCGGTTGCGGGATCAGTCAGTCCGAATATCTCGAAGCAGTCTCTGGTGTAGACGGCCTTGATCAGATCTTCTTTGGGCAGGCTCGGATCGACGAAGGGTCCGTTTTGCAGGTAGTCCCCGAGCAGCGTCGCGCCGGTACGAGCAGCTTTCACCGCGAACATGAGTTCGGGCAAGCTGGCTGCTGCGGCCTCGTCGACGATGACCATGTCGAACGCCGTGCTGAGGATCATCTTCTTGAGCGTCAGCATGCTGAGCGTCGTCGCAATGACGGCGGCCTCGGCAATGAGCGCGGCTTGCATACCGGGCCGCTTGTCTGCCAGGTCGGTCACGAGGCGGTCGTGCTGTGTTTGGCACTCGCGGATCTTTCGGTCGCACTCGACAGCGGATTGCCGCAATGCGGACAGCTCTTCATGCAGCTGCGGCAGACCGCGCATTTCCGCCTCGCGGAGCAGTTGCAGATCCTGCTCGGAGGGCTGTGCTGCCGCAGCGGCGATGCTCAGTCGCTGCCGAACCGCGGCCAGGGCTTCGGCTGCGGCTTCTTTTACCCGGACCGCTGTGCTTTGGTGCAGCTCGGCATGCGCGGCCCACTCGTGGGCTTGGGCAATGGTGGCTGCCTGCGCTTGGACGTAAAGGGCATGGGACACCTCCGCGCCGGCCTGCCGTAACCGGGCTTCCGCAGCGGTCCGCTCCGTCCGCTTTGCGTCCAGTTCGCGCTCGGCGCGGTGGGCGGCACCGCGGGCCTGTCGGCGGCGCATCGTGGACATCGCCCGCGACAATCCGGTGCTGCGTTCCTCCTCAGCCAACCCCTGCGCTGCCTGATCCCGGTCGTGTCGAGCTATGCGCTCGTAGACCATGGCGACGAGCAGATGCGCCAAGAGTTCGTCGGCAGTCGCTTGCTTGAGGTTACCCTTCGCCTCAGCGGCATGCAGGGCCGCTGCCTGTACCTGGGCGGTCAGCTGCTGCGCTCGGTGCTGATTGTCCCGCCGCGCCTGGCGGCGTCGATGCTCGCTAGGGTCGAAACCCGCCAGTGCAGCCTCCGAATCGGCGAGCCGGCGCTGCGGATGATTGCTCTGCAGCTCCGCGATAGTGTCCTCCAGACGGCTTAGGCGCGCCAAGGCGGTGCGTTGGCGAGCTTCGACCAGCCGGTTTAGCGAGACTCGCTCGTCACGGGCTACCGTAGTGATGCGGGGAGTACCGACCCGGATCACTCGGCCGGCGGTGGGGGCAAGGCGTTTGATGATGCCCTCGACGGCATTGTCGACCGCCACGTTGGTGTTCGATACGAGTAGCACTCGCTTTCCCGCCGTCATCAGGCGTTCGATGGCGTTGACGATGACATGAGTTTTCCCGGTGCCCGGCGGGCCCCACACAACCTGCAATCCGGGAGCGCAGCAGGCGTCGGAAGCGCGTTGCTGGGCGTCGTTGAGCCGGGGGTCGCATGGCCCGGCCGGCGGTAACGGATCCAGTCGCTGCTGATCGAAGCGGTGGACGAGATTGTCCGGTGCGAGCGCGCTCAGACCCTCAAGCACTGCCGTACGCGAGGCGCGAAGATCCATCGCTGGAACCCAGAACGACAATCCCTGAGCCGGTGCGCCGGACTGGGTCCGTACCCGAAGGACGCCGTCCACGACTTCGCTGTCGATCACGGCGAAGCTTCGCTGCTCGGGACCTTCCTGTGGCGCCAGGCATGCGCCATCCATCCGGTCAAGATCGCCAGGATTGAGCCGGGCACGGAGGCGGTACCAGCCCTCACCTCTGGGGCCGTCTGAGTCGACTCGGCCTCGGAGGACGAATTCGGAAGAAGGCTTCAACGTGCGCTGCGCCGCTTGACGAACTACCGCAATCACGTCGTTCAGTGACGCCATGACACCTCTGTTCGTCACCGAGTTCCCGCAGGATCGGCAGTCCAACTCCCGCTACGTGGCGTCCTCGTCGCCGACTAGGACGGCGGCTCGCCGAAGACTTCACGAGTCGGCCGCCGATACAGCGCGAGCAACGATGGCTATGGCGCGTCATCGTCGCCGATCTCGCGCCGCGCCAGCCGCAGCATGCCCAGCCTGCTCGGCACGGCAAGACACCTGACCACGATGCCGCGGTACGCCGCCGGCCGTGATTCACCGGGGTAGGCGCACCAGGGTGCTTCATTCGATAAAGCCGGATCCCGGTTGTGCACAGCGGACTCCTCGTCAGGCATGACTTGCAGTAGTCGCAGCGGGAGGCAAGCCGCGAACGTTCACCTGGTCCGGAGACTGCCTGCCGCGGCACAGTCGGGACAGCGCCGAAAGAATACATGGAGTGATCATGTGGCTGGAGCACGCCGGTGTGCCGATCTGAGCCTCCCATCGGTCAACGTGAACAGCTCCGGCGCACTTCAAACGCTTGATCAGCAGCTTTGCACTATGAGATCAAAGCGTGTGGCGTCAGAAATGTCGTACGGCCATGCCATCATGCATCGTCGCCTATCACTACTTGATCACGGAGAGTAGATCATGCCGCACGTCTCCGGGCACTACCGCAACGGCCGGTGGGTCCGTCCGCACTACCGACGAAGCACCCCCAGGGCCGTCCGCAGCGCCGGAATGATTCGCGTACGCGGCCACCGCCGCGACGACGGAACGTACGTCCGGCCCCACCTGCGCAACGCCGCCCCGACCCTCACACCGGCCTCGAGCAACTCGGACTGGGACTGGCTGGGCTACCTAGCCATGTTGCTGTTCGTCTTGTTCCTCATCGGCGCTGCAACCCAGGCGTAAGGAGTCCCTCGACTATGCCGATCGTCAAGCCGCATACCCGCCAGGGCAAACCCGTCAAGGGCTACTACCGGCTCAATTCAATCTGGAACTTCTGGTTCGGCTTCCTGCTCATGCTGCTGCTGTTCGCCGTCGTCAGCAAAGGAAACTAGCAACGTCGTCCACCAGACCCTGGGTTCTCACCGGCTACGCCAACCGCCCCTCTCCTCAGCGAGAGGGGCGCGGCGCTCGAAAGCCGGACCGGGTGGCATGCGCTGACGGTGACCCTTGGGTTCCGACTCCGGCAGATGATCAACTTCGATGGGCTCGGAGGTGCGTTTACCTTCCCCTCGCGTTTAGGAAACGACGGCGGACATCGATGGCCCGAGCTTCGTCGTCCGCCGCCGGAACGGCTGCGGCCCGCCTTCAAGGTGGTAGAGAGCGTGGCGGTTAAGGTCGTAGCGCTCCAGCGATCCGCTCGCCTCAATGGTCCCCTGCGTGGCCCCAGACGTCAGCGTGATGATCATTTCCGCGTCGGCTGACGCAACCAGGCCTGGACTACGGGTGGCAAACACATACTGACGGCTGCCACGCAGTCCACGGAGCCGCTCAACGAGATACTCCTCGATCCAGGGAGCATGCAGCGCATCCTCTGGCTGATCGATGATCAACGGTTCAGCACCATCCGCCAACGCGATGATCAGGATGGCAGTGCATTTCTGGCCGTGCGCGAGCCGTTCGATGTGCTCGTACTCCCCTTCGCCCCGCTTGCGGAACTCCACCGAGAGCCCGTCGAGCAGCTCAAGCGATTGCAGGCCGAGGAATTCTTCCTCCTGATGCCGCTCGATGACATGCTCGAACAAGGTCTGGATGTGACGGCTCTCAACGCCGGTCACCTTGCTGACGCCCTCTGCGTCATCGTCCAGAAAGGAGCGAATGAGCTTGACGGGGTGCGACTTCGCGCACAGCTGCTGCAAGACGTCCGCACGAAGACGAGATCCTTTCGCGAGTGCCGCGATCTGCGCTCCGTAGTCTTCGTCCTCACTTTCACTGTCCAGCTTTATCCGCACCACGCCCGACATCAGCTTGTTCAAGAGCCTGATCCGGGTCTCGCGGCGCTTGCGGCGCTCTTTCCGCAACACCACCAGTTCCTCAATGATGGTTTCGCGGTGTTCCATCGCCGTACGCAACCCGGGACGAAGCGTCGTCTCCAGCTTCGTCGCAACATCATCGAGCGTGACCTTGTTCGTTTGCAGCTCGGTCAAGCGCGTCCGGAGCGTCTCCAGGCCCTTGCCCTCGACGTCAGCCTCCGCCACGACCGCCCGCAGCTTGGCGTCGAACTCTTGTTGCCGCTCACGCCATTCCGCGACGATGCCGGCCAGCTCCCGGCCTGCCGCCGCGTAGGCCTGCTGAAGTTTCTCATCAACGGACTTGAGCGTCGCCTCCAGTGCACTCAGCGCCGTGGCCGCCCGGTCGTACAGGTCCCGGTTGGCCTCGACCGCAACCGCGTGCACGAACGACATCACCTGGGGGATATGTGGCGCCACGAGCGCATCGGCAGATGTCAGGGAGTTGAACCACGTACGCTCTCGGCTCCAGGCGGCCTGTTGCCGGACGATATCGCCGTTGAACAACTTCCCCAGCTCGGTCAAGCGCTCGACGACAACGGGACGCTGCTCCAACAGGAGTTCCGCCTCGCGGATGCCGTCACGCAGCCCCACAATCAAGCGGCTGTTGTCCGCCAACCGGCTGCGGACTTCGAGGTCAGCGGCAACGAGGTCTTCCAGATCAAGGCCCGAGTCAATCAGCGTCATACGCCCGACCCGGGTGCGTGCATGTTCGATGACCTCGCTCTGCGAGAAGGCCCGGATGGCAACTCGACCCGAGGGGTTCACGAAGTGCTCCGTGTCGCCGGACATCTCCGGCGACGGTGACTGATCGCCGAAGTAGGCGCGTCGCACAACGCACCGTGCCCACTTGCGGCGCAGCACCACCTCCACCGATGCGTTCTGGCTCAACGCATGATCGAGACGTGAGTCCACTTCCCGGCGGACCTGGGGAAAGTCGGAACTATCGGTCTGCTGGTCCAGCGCAAACCGGATCACCTCGATCAACAGTGACTTGCCGGTTCCCGTGCCCCCCAGTAGGCAGTTGAGGTCTGCAGACAGCTCGAACGTCTGCCCATCGAGAAAACCGCCCGAGACCCGGACAGACTCGATGATCATGTGCTCCGGCTCTGCCGGCTCCTCCAGTCGGACCCTCAGCTCCGGGTCAGCGAGGGCATGCTTGAGACCACAAAGATCCGGCCGGGAAGCCTTCACCCACGTCCGCCGCCGACCGATGCCCTCCAACACGTGCACATTCCCACCGGGAATGGTCACGTCCGAGCCCCGAACACAGGCCATCTCCCGTCGGCCGGCAGTCTTCGACGAAACCCGCTCGGCCGCCTCTGGATCAACGATCTCCACCCCCGCCAGGGCCGGGTTGAGGATGATCTTGCTGACGTTCGCGGCGACCGTCAACTGAAGGAGACCTTTAGGACGGTCGGCGTGCGCGGCGATGGCGATCCCACCACTGCGATGGACCGCTTCGGCAGCCTCAGCGAAGCCGCCGCGGGTTGCAACGTCCAGCCTTCCCTGGTCTACACGAGGTATCCCCAGCTCGACCAGAACGTCCTCCATGAGATGCAGCGGTGTCCCTTCATCCCACACCGCCAGCAGATGGCCTTCGGTCGTACTGATCTCGATGCCAGGTAGCACGATCAAAGACGTCGCGGTAGCGGCCGCAGCCACCAGATCGCACCACCGCACTGTGTTGTGATCGGTGACAGCGATGGCGTCCAGCCCGGCGGAGAGTGCCGCCGCCACGACCTCTTCAGCCGCGGAAGCCCCATACGTCAGCGGATCAACATCTGCCGACCCCGGCGTGTGCACATGAAGGTCGACGGCCCAGAACCGTGCCGGTGGATGCATACCCGTCATCGACACGGCATCCGTCGACGAACGATGATCAGAGAACATGAAAGACGGTCCCCGCTGCATCAACACTGATCTTGCTCGGCCAAGGTCTTGGTCACGGTACTCCGCCGGATCCGCAACGAGCATCCGAAAAGCCACCGTCGCGCCGGCCCGCAGCAACCGGTTTCTCCGAATCCAGGCCCGAGCAACAGCCAGATGCGGCACAGATTTCCGCAGCTAGCCTCCACACCAGTGATTCCAACTAGTCGATGAGCACGACGCGCAAGCCCGGCGCATCACCAGGCGCCCGGGGCACACTATCGCCTTACCGAGTGACAAACAGCCCCAGCGAACAGCGGGACCTCGAAGTCATCGATGTACTCTCTGTAGTCTTTCGTGCTTGCACGCGGCGCGTTGCGCACCGCTAAAGGCCAGCACAAGGCACTGACCCACCGCGGATCAACAGTCTTTGACACGCGATCACCACCGGATCACCACGGTCCCACCATGCGGGACTTTCGGGGCTGAAAATGGGAAGAAAAAAGGCCGTGACCCTTGTTTCCGCAGGTCACGGCCTTGATCTTTTGTGCGCCCGAAGGGACTCGAACCCCTAACCTTCTGATCCGTAGTCAGATGCTCTATCCATTGAGCTACGGGCGCTTCTCTTGGTGCTCAGTCAGCATACACACCGACTTTTGCGCGGAGACTCCGGGATTCGAACCCGGGAGGGGCTTTAAAACCCCAACCGCATTAGCAGTGCGGCGCCATAGACCAGACTAGGCGAAGTCTCCTCGGTGACCTGCGAGAGTCACCGAGGACTGAGAATACCGGACCCGTTGAGCGTCGCACAAAGAGGTCGGCCCGAAACCTCCCGAAGATCTGCCACGAAGGCTGCGAACAGGCGAAACGTTGCGGTTGCGACTACGCTGCGCAGGATGGAGGAGAAGCAGACGCCGCGTGCCAGGGATCCGCGGGCGCCCTTCAGTGCGCCGGAGGCGGAGCAGGCCGGTGGGGGGCGGGGGCGGCGCGGGGCGCCGCCGGCCGTTACTTTCCAGCCGCCTCGGCCTGGGGTCAGTGCTGAAGGTCACCCTTCCGGGGCTTCTTCCGGTACGCCGGAGGACAGCGAACCGCCGCGGCCGGCAGCCAAAGCCGCGGGGCGGGCCGCCAGGACTTCCAGGGCCGCGCGCACCGTGGCGCCGGTGGACAACGGGGCGGCCGGAGCGGCCGACGGGCAGCCGGAGCGGGCTGCGGACGGGACGGGCGCTGCGCGGAAGGCGCCGGTCAAGAAGGTGGCGCCGCGGTCCCGGGCGGCGGCGAAGGCGGTGCCCGCTGCGAATGATCAGGCGGCGACCGGTGACCCGGCGGCTGCCGAGACGGTCAAGCGGGTGGCGCGGCCCCGGAAAGCAGCCGCGGGCAAGCCGCCGGCGAGCAAGATGCCAGCGAGTGGAGCACCGGAAGCGGTGAAAGCGGACCGGACCCCGACCACGGCGGAAGCGGACCAGCCGGCGACCGCCACGGCACCGGCCATGACCGCACCGGCACCGGCCACAACGGAGACCGACCAGGCCGCGGCCACCACGACGCCGGGCACGGCAGAGGCGGATCGGGTCACAGACGCCGCGACACCGGGCACGGCAGAGGCGGACCAGGTCACAGACGCCGCGACACCGGGCACGGCAGAGGCGGACCAGGTCACAGACGCCGCGACACCGGGCACGGCAGAGGCGGATCGGGTCACAGACGCCGCGACACCGGGCACGGCAAAGGTGTACGCGGTCGGTGCGAGCAGGACGCCGGTGGTGGGCAACGCCGCGGAGCGGTTGCACTGGGCGGTGGCGGATCAGATCGTGGTGGATCTGTGGCCTCGGCTGGTAGCGGAGCCGCGGGACGCAGCGCGGATTCTGGCTGAGGCGGCGGTGCAGACCCTGGGGCCGCGCGCGGCGGCGTGGGCGGCTCGGACCCGGGCCGCTTATCCGGCGGCTACACCGCAGGGGCTGGCACGACTGGCGACGGCGCAGTCTGTCCGCGCGGCGGAGCGGCGGGGGATCCTCAGCGCGCTGTCCGGGACGTACGCGCCGATCGCTCTTGTCGCCTCGGCCGCGTTGACGCACGCGGACCTGGTGTTGCATGTCGCCGCGGCGTATGGGGTCGATCCGACGGATCCGGAGCGTGCGGCGGAGCTGGTGGTGCTGCTGCCCAGCTATCGGGGCGGTGCGGCGTGGGCGGCGCTGCGGCTGGCCGATCGGGCCTTCCCGGGGGCGAGCATGCTCGGCGCGGTGCTCGGCGGGCGGAACACGGCCGAGGCGGTGGCGGTCCGCGCGGAGCGGCGGTACGGGTGGTACGCGAGCCGCAGGTCGCAGGAGTAGCAGCCTCGCGGCGAAGCCCCGGAAACGACGACCCGGACGGGGCCGGAGATGGCGAACCCCGGGCGGAGCCGGAGATGGCGAACCCCGGGCGGAGCCGGAAGTGGCGGAGCCGGAGACCACCCCGGGCGGGCCCGAAGTGGCAGCACCGGGAAACGACGAGCCCGGGCCGGCCCGGAAATCGCGGCGCCCGGAACGAACGGCTACGGGTGGAGCCAGGTGAGCCAGGAGTCCGGAAGCAGGTCATAGCCGACGAAGGCGGTGATGTCGAGGATGCTGTGGGCCACGATCAACGGCATCACCCGCTTGGTACGCAGATAAAAGAACGCGAAAATCACCCCCATCACGATATTTCCGACGAATCCGCCAAAGCCTTGGTACAGGTGGTACGACCCCCGCAGCACCGCCGACCCCGCGACGATCCACCCGGTCGACACCTCCAGCTGCCGCAGCCGGGTCGTCAGATACCCCACCACCAGCACCTCTTCGAGCACCGCGTTCTGCACCGCCGACAGCACGAGCACCGGCACCGCCCACCAGTAGGGCTGCAACGCCGACGGCACGATCTGCGCCGACACCCCGAGCTTGATCGCCGCGTACACCAGCAACAACCCGGGGAGGCCGATGCCGGCGGCCAGGCCGGCGCCCCAGCCCGCATCGAATCCCGGGCGCCGGAAGTCGATGCCGAGGTCTCGGCCGGGCCGGATGCCGTCGCGGCGCAGGAGATACCACGCCAAAGCCACCGGTACCAGGTCGAAGAAGATGTTCAGCACCTGGTACGTGAGGTCCAGGTAGGGACGGGGCGACATCGGCGCGTTGAGTGTCGCGGTGTGGCTGGCCAGCGGTTTGCCGTCGGTGAGCTTGGCGGTCAGCGACACGATCGACCAGATCGCCGACTGCCCGAGCGACAGCAGCAGGACGATGGCGATCTCGGCGGGGTACGCCGATCGGGTGGACCGCTGGCCTTCTAGAGTCAC

Protein sequences of DBSCAN-SWA_4

>NZ_LT827010|9045686:9090307|9072891_9074544_+|WP_155123729.1|DBSCAN-SWA
MTFADLRDARVDRLTVAADVWRQLAGKCSKLEDRTELELSKPLQNGAWEGAAATEALRRMTSLEDEFSLYRMKARSIGMLLERIATDFQGLQQRLQSAIDAATSLGLTVTADGRVQADEVPQSALSDPGALEVNRLANQNADVYTEVIASILKDADHIDLTYAGMLRDFGPDVQGPNEFSWQHTTDAARELAGLNGLTADDITAAGTNPAQAAAWWHGLTADQRELLSMAYPAEVGRLNGLPATDRDTANRLALHELIGQGVNQRVDPNDPQHQRLVNLMNRLDAADYQTGKPLYLLSIDNQGTGRAAVAIGNPDTARHTAMLIPGVTNNLDGMVDQIGRADHIRDAAELLGASDVSVIAWLQYDPPQLDDSIVTAAGSDRAQEGATNLLAFTDGLRVSHDAGPVHMTAIGHSYGSVVVGDATSGGHRLAVDDVVVVGSPGMDVHRASDLSVGADHVWAGAAPDDMVASPDTAIPLETGIPVAGDGVQAAIRLKHGVEPHLPEFGARVFMTDTPGHTSYWQAGSQSLKSQASVVVGDYGNLIPRYGKFPS
>NZ_LT827010|9045686:9090307|9065337_9067194_+|WP_014695160.1|DBSCAN-SWA
MGWLSKRRLARRLLVNAITIAVLVAVAVLGYSVSHRQETMAGQARQAQRLAESAQQVKFRAADFNGWQTAYALDIIRAVPGATADTSPSRAKFLDAAAKFDSELDALEVLSASSPSARTVDAVREAFEAFMTLDRTVVTLYRSGKPADRRAASELVLGREIQLYGQIANGCDATAALSAAAADTSIGRLDAVGAAIRRYILILSIVAAALTVLGAILAEARQRAIAQQAKEAQRMASLGRLAGGITHDFNNVLAIILNYTDFVAEHASPEALDDLAQIRKAAKRAAGLTAQLLCFIRHEAIQPQIFDINAAINEAHAMLARTLGEHIELVVMPSPEPLKICADTGQIQQILVNLAVNARDAMPDGGTLVIAASAVDLEENQANVHPPVAAGRYLQLLVTDTGTGMSPETVARIFEPFFTTKPKGHGTGLGLATVLDIVITAGGSIDVCSKLGIGTTFRLYFPAVDVPYGQESEGRNDVAPPRGHGQSILIVEDEPALGTSVARILAAGGYQVRSAVSGPDALAAYADDGCDLLIADVVMPDMSGSRLAEILHRTDPRLPVLYISGYIDGNLGANRLCTPETRVIEKPFTADQLLVAVGDALSPAPDENGITGGRPRPV
>NZ_LT827010|9045686:9090307|9045686_9047549_-|WP_014695142.1|protease|DBSCAN-SWA
MPKKTTRRRIASALTGVSVAAAAVALVQLPASAAGSTGGSALLPPIPANARHFALPYDKIPAGAVKAKTGPLKAGKRAKAFQTPGSKTKIVNGDIAHSADFPGVVGIQSDFIANDANGNPAWWTSTCTGTVLSPTRVLTAGHCTVDLPYGYTQVIAGRDNLADNTSGFVARVSNTWLHPSYNYQAQVTDPQNTPPKNDVSVLDLKDALPDVYKATDLIAQGAADPAAGQDATIVGYGITKEGGSDSGVLHSATVQTQKDSTCTQPSQFGTQFDPTTMLCAGDVVNHKDTCHGDSGGPIFLGGPAARVEIGVTSWGNVCGGAYYGAYAALNQLSGAVKAQVTNLQPTNLDFTGDGHSDLIVREPGTGYLIVASGAGTLVGTPYIDETSSYDVGFNYYRYLDKSHNYEAYSKLFRVTNWNADGNESIFGRDRNGTLWQWKGDGRGDLVSTTPTKIGSGWNMFTDIVVTNNWNGDGRSNLLGRKADGTLVIYNSDGAGGWENPQGTVIGSGWNQFNTVLTPGSWLGDGHQSLIGRNAAGELWLYNSNGHGGWINPRGTKLGTGWNGMPTFMSPGDFDGDNLVDLIGVRTNGDLYLYPTNGKGAWKNGRGKLLGYSWDYYKAVF
>NZ_LT827010|9045686:9090307|9053070_9056088_+|WP_014695148.1|DBSCAN-SWA
MSSTSADQRKRDAQRQWGADRRTDPHPIVPPPVSEGRITRGRLAIVVTITVWAGYIAYTIFEQFIVGKAYNARLGAEAIAYMLVITGLAASAIAYLITRIGYFYRGRGHQRAPRIMLDEFIGGKTPSLTVLVPSYQEDERTNRSTLLSAALQEYPGLRVTLLIDDPRAPKTRAARDMLLAARALPGKIEAELQVPYRRVAAAFAAFDEQVRFRGGHLVVPDDMRRLADEYRFASDWLYDLGARQEMVDHTDTFFVEHILHPLAVELGQIAGALVKGADEQVALPLPRMNQLHKRLLAIFDAQVTSFERKKYVSLSHEPNKAMNLNSYIGLMGGAYQEVNTPLGTALVTAGPNRADLVVPNPDYVLTLDADSVLLPEYALRLVHLMEQGAFAQHAVVQTPYSAYPGSGTRVERISGATTDIQYIVHQGMTHYGATFWVGANAVLRKKALDEICEVSYEGDWEIKRYIQDRTVIEDTESTIDLGVRGWTLHNYPERLAYSATPPDFGSLAIQRQRWANGGLLILSRLKDQFKAKSKREDKNRFGEYFLRVNYMASIFWSSMCLVIMLVYPFNNELLNPFLLLISVPYFFMMAADLKHLGYKRTDMLRIYGFNLILLPVNLSGSIASLLQLLTGEKSAFKRTPKVRNRTTTATSYLLLPLALVVLCLYTVWHDVRLHQWNNLVFAGLNLVLSLYAVIAFIGLGNTVVDLATHLRDWLVPVATPKKVRKSSASKKAAAPKAAAIGDWATVLHYRHETGATAGQVTVRLQRTDTGAWKTDRPTSASRAHLFEEFSFFTVFQPIHNMINGHVVGYEALTRFADGSNPREGLEAAAQRGVHVALDAALVQAAIASSSSLPNGTWLAVNVSTDLLRRPHELAPLLAEAKRPLIVEVGGPVPAEVGQLGGTVRLAVDDLGLGYETLALLESARPAFLKLSLDTVQNLENETARQASIRTLVEFAEQHGCTIIAEGIETAAQRDALVACGVPFGQGFYLGKPVPVERVLAGVGGW
>NZ_LT827010|9045686:9090307|9061161_9061365_+|WP_043513155.1|DBSCAN-SWA
MIGADRVRTSIDYGGTSGTGFHDYVFFVVHTGSVQIDSPLGGTVASAADVAFYPLGFRSSSTCTTST
>NZ_LT827010|9045686:9090307|9051284_9052889_-|WP_052311846.1|DBSCAN-SWA
MTDRATAVAARTGIDPLADPDWQEPEQPRRRLSWTRLGMLVLALGAVGAGGTLGVMHLRDTSGPTAKSWAVPYVDVTLTPTFQFQDPTANPAKNVALGFVVADPKSACAPSWGGAYSLDAAATSLELDRRIDQLRQAGGDITLSLGGLANQELAVACADQAKLTDAYRQLVKRYDVKTLDLDIEGTAVADQASLQRRVTAVAAVQKEREAAGKPLAVWLTLPVTPNGLTDDGVGVVRGMLDGGVALRGVNVMTMDFNNGDSHPNMLGLSTSALDGTHKQLTDLYLRLGQKLTSPQVWSRIGATPMIGQNDVDAERFTVDNATGLATFAVDKGLGRVSMWSLNRDAPCRGTFANVVVHSNTCSGVDQDALAFSKVFAGLPGKAAGSSSQDSVDIPNQAATVDDPKTSPYPIWRLTALYTGGYKVVWHGVVYEAKWANSGVDPSAAPAAGTQNAWSVIGPVSPVEKAPKPTPAVTGVTRIWTPGTAYQRGDRVLLNGLPYEAKWTTKGETPSTEFPIDADDPWHPLFNVPGEPTTN
>NZ_LT827010|9045686:9090307|9069648_9070227_+|WP_099343963.1|transposase|DBSCAN-SWA
MARLRAENRRLPQDVDILKRTAFFRAGDPVNVYPFIEAEQTGKHNVKRACELLKVSRSAYYQHARGEQSTRDRVDARLTEQIIAVHAASNGTYGVPRIHAKLAAAGLRHGRKRVARRMRAAGIAGKCPRRWKTTTVADPHAGARPDLVDRNFRVDATAVDTRWCGDITYINTWEGWLYLATVIDLASRRVVG
>NZ_LT827010|9045686:9090307|9060052_9060934_+|WP_014695154.1|DBSCAN-SWA
MRVGELARRTGTTIRALRYYEQVGLVVPRRLGNGYRDYEPIAERQVAQIRELTALGLTVEETRPFVESIANDDDVCAAAVATFRSTVTSLQTRIGELTTQREALDARIDAAAHRIVAGTPVTGGPPAGLIGRRLPELHFYATDGRPLRLDHLGPGRSVIFVYPLTGRPGVDLPRSLLEIPGARGQGDWLRDHHAEIRTAGAARVFGLSAQSTGYQRELVHRLRLPYPLIPDPKLTLAAATGLPVHTTGDLAVYERLTLIVRDDRVEHVFHPIPDPASHALHLMRWLTQRRSGG
>NZ_LT827010|9045686:9090307|9069429_9069591_+|WP_014695163.1|transposase|DBSCAN-SWA
MESVGKKRSRPRRAFTPEFKAEIVELCQRGDRTVGQVARDFDLTETAVRAWVK
>NZ_LT827010|9045686:9090307|9062203_9063061_-|WP_014695158.1|DBSCAN-SWA
MRESSGHPAPARSASVTVEALLARRGRIQQGLIDAEIRATRRAILTQFRLRLRADVGTLSSTAFLTLADEPAVHTAIMIAVSGVARPDALLLHTCAPGAAPLRLTRHRGLPESGPHQVARIGSAVASVVPPEGDSAGPVVVHDLSAAVVGVSRLATRMLLDAGFRAVQCYPMRDGDGPRLGLLSLLYRSPDRYPVQESLARHAGKALAHLSETRIGTCPVVAPSAFPGPPASPPDAACLSGLLAVEPSRPGAKRSNPQGRGAKRWAGERSGRLAGVDGKPLSGAR
>NZ_LT827010|9045686:9090307|9076263_9076821_-|WP_014695171.1|DBSCAN-SWA
MPIADAEIAAAVAAYLDRYPAEKALLAEPIELLARGSNFASRRNFDLHVTVGALLTRGGEEILLVGHRAYGIPLQPGGHLEPSDTTLMGAAVRELAEETGIDPTTVTTASATPVYVEFGRVPARPQKDEPEHFHLDLGYAFTTTGDVGSLQESEVTSAAWYRLDEAERLVGSRVWRACNPSVRIG
>NZ_LT827010|9045686:9090307|9056223_9057381_-|WP_014695149.1|DBSCAN-SWA
MLGRSGRRWAQVAMAAAAGGALLLGAAAPAAADEPTTGVPSRMTDGAVTLVLGGKAHSVGGIQFTIKGQTVPIFCIDYHTGLAANEPYTEGTWDESEVKNLTKVQWVLAHGYPNGDINALLTAAHVQMPQLDEARQRKLLYFGTQTAVWHFSDGIDLGAYSDGARLTDKPQYDVVKGIYDYLTTNAVDQPEPAAQLTVTPASATAKAGEKAGPFTVAGPASAISVSVKGGSAVDADGKPVTSTSNGGKFWLTAADAGKATVTLNAEDSVSFGRVFLYSGGKDKHQKLILGSSIGKPVTASAEATFTPAPVTTTTAASPKPSASTSKASQSPSAAVPGASTSPTSGGHLALTGSAASTVAGGGVVLLVIGGLALMLVRRRRTRFTS
>NZ_LT827010|9045686:9090307|9072579_9072885_+|WP_014695167.1|DBSCAN-SWA
MGDELHVEPAVLHSARQVCEDLGVAWRRDEHGVEPVTEDAAAGLPGWMTGRALGDFVWYWQDDVKKLTGYLETFGDALQRAALTYEHTDHASADLFDIRGR
>NZ_LT827010|9045686:9090307|9048077_9049214_-|WP_014695143.1|DBSCAN-SWA
MFGYRVPAPNEALLISGRKQRGADALPFKIVTGHGVFVMPVFSKATRLTLAMQEAEVVEDCYTKQGLTLGVQAVIAFKVGDDHESIAAAARRFQGDQGQMPTLVGRIFSGHLRSIIGSMTVESIIREQQTLADAIVDASKTEMARIGLAVDSLQISSIDDKGVGYIKALAAPHQARVNQEAQVAQAAADRESAMAQQESARHQAEYSRQTAIAKAQFQAEIDQAQQTASQAGPLAAARAAQEVLAEQALVAQKNAELRQAQLIAEVVRPAEAEAERIRALARAEADATKLSAEAAAAQDRIALDQAIIDKLPEMLRAAAEGLQGANVTVLDGAEGLNSVVASLAAQGMTMLETLRSGMRPEPAQPGNAVAPINAKSVA
>NZ_LT827010|9045686:9090307|9057862_9058054_+|WP_014695151.1|DBSCAN-SWA
MKRTLAVALMLGALITGGCDRGAPRATNPPAPAATQADDGVDSLLDDAGTQLSHDDQPAEDED
>NZ_LT827010|9045686:9090307|9049216_9049438_-|WP_014695144.1|DBSCAN-SWA
MTRETLVGRIGTVITAIRGGERAGEVRLVVAGIAHYYLAYAAAPVPPGSEVLVINHRGARQIDVEPWPIEEGL
>NZ_LT827010|9045686:9090307|9084366_9087030_-|WP_099344252.1|DBSCAN-SWA
MFSDHRSSTDAVSMTGMHPPARFWAVDLHVHTPGSADVDPLTYGASAAEEVVAAALSAGLDAIAVTDHNTVRWCDLVAAAATATSLIVLPGIEISTTEGHLLAVWDEGTPLHLMEDVLVELGIPRVDQGRLDVATRGGFAEAAEAVHRSGGIAIAAHADRPKGLLQLTVAANVSKIILNPALAGVEIVDPEAAERVSSKTAGRREMACVRGSDVTIPGGNVHVLEGIGRRRTWVKASRPDLCGLKHALADPELRVRLEEPAEPEHMIIESVRVSGGFLDGQTFELSADLNCLLGGTGTGKSLLIEVIRFALDQQTDSSDFPQVRREVDSRLDHALSQNASVEVVLRRKWARCVVRRAYFGDQSPSPEMSGDTEHFVNPSGRVAIRAFSQSEVIEHARTRVGRMTLIDSGLDLEDLVAADLEVRSRLADNSRLIVGLRDGIREAELLLEQRPVVVERLTELGKLFNGDIVRQQAAWSRERTWFNSLTSADALVAPHIPQVMSFVHAVAVEANRDLYDRAATALSALEATLKSVDEKLQQAYAAAGRELAGIVAEWRERQQEFDAKLRAVVAEADVEGKGLETLRTRLTELQTNKVTLDDVATKLETTLRPGLRTAMEHRETIIEELVVLRKERRKRRETRIRLLNKLMSGVVRIKLDSESEDEDYGAQIAALAKGSRLRADVLQQLCAKSHPVKLIRSFLDDDAEGVSKVTGVESRHIQTLFEHVIERHQEEEFLGLQSLELLDGLSVEFRKRGEGEYEHIERLAHGQKCTAILIIALADGAEPLIIDQPEDALHAPWIEEYLVERLRGLRGSRQYVFATRSPGLVASADAEMIITLTSGATQGTIEASGSLERYDLNRHALYHLEGGPQPFRRRTTKLGPSMSAVVS
>NZ_LT827010|9045686:9090307|9061964_9062198_-|WP_043513158.1|DBSCAN-SWA
MSLDSDFTGTPGQRAAACLAFAARARARADQLERTAQTLIDRAAVAHRAAEDASARVTGSYPAARRQLLNVSLGDTP
>NZ_LT827010|9045686:9090307|9058657_9059932_-|WP_014695153.1|DBSCAN-SWA
MTAISRVIGRQILDSRGNPSVEVDVVLADGSSGRAAVPSGASTGANEAVELRDGDPERFHGKGVSRAVAAVNGAIAAAVTGLEAEDQALVDTTMIDLDGTGDKGRLGANAILGVSLATAKAAAQAHRQPLYRYLGGAGARTLPVPMMNIINGGAHADNPLDFQEFMIAPIGAENFFEAVRIGSEVFHTLRRRLAAAGHSTNVGDEGGFAPNFADADEALRFVVQAVRDSGYRPGIDVTICLDPASSEFYRGGAYEYTGEGRTRTADEHIDYLLELAAAYPISSIEDPMAEDDFAGWRKLTAQAGDRIQLVGDDVFCTDADRLQSGIDGGYANAILVKVNQIGTLTETLRTVETAHRAGYRVVISHRSGETEDTTIADLAVATNCGQIKTGSLSRSDRTAKYNQLIRIEEQLGRSARYGSATSSR
>NZ_LT827010|9045686:9090307|9050409_9051075_+|WP_014695146.1|DBSCAN-SWA
MKKYDTRTAIAAVIDIPAGRVQVIAADRTDTVVEVRPLDAAKSRDVKVAEQTAVDFTDGILRIVAEAKNQIFGASGSVEVTVQLPAGSRVEVRAASAEFRGAGRLGDVVHRGAHGAIKLDEAASADVSTDAGDVTIGRLTGAAEIRTQKGDIRIAETSGGDLTLSTQAGDITVDTAAGVSASLDAGTSYGRIVNSLRNAGGEVEVAIRATTSYGTITARSL
>NZ_LT827010|9045686:9090307|9070223_9071222_-|WP_014691959.1|transposase|DBSCAN-SWA
MPHRNAPLSETGRLRLARCVVDDRWPLRRAAERFQVSTTTAKRWADRYRTDGPAGMTDRSSRPHHSPSQTPTRTERRIIKVRILRRWGPARIAYFLSLNPATVHRVLTRYRLARLTHLDRATSRPIRRYEHDTPGDLVHVDIKKLGNIPDGGGHRVHGRADGNRHSSAHRDPARPRTHHGRPNLGYHYLHNAVDDHSRLAYTEILPDETRETATAFWQRAHAWFTSRGITVKRVLTDNGSCYRSHLWHDALAAAGITHKRTRPYRPQTNGKVERFNRTMLDEWAYARAYRTETERREALPAWLHTYNHHRGHTALNGLPPASRVPNLSGQYT
>NZ_LT827010|9045686:9090307|9078079_9079171_+|WP_014695172.1|DBSCAN-SWA
MTDLNEAFGAVPVLAYTDHERYGPTVHRSVPEWIQREVTSLRVQAGHRVLEIGTGSGYSGALLARLCGPRGRVTSIDISEELINRARAIHAERGVTEIDCHVADGLAGFPTAAPFDRAVGWCTPPRLPRTWVEQITDGGRIVASLPIAPLPSTALITTITVDAGQPRVQAVVGGVYAQSTPAPVDDAVTVPGRWVDYCDRQPDPSWIAISWRTEDPHNSGARAALDRLLNPGHTETYGDMEADWRSWSAHTAAPPDPGLSMVSLRNQIRGIGHTTATSAAVILTDGTIIADTPDSASLTVLREWLILWQQAGRPTADSFIPRLVPNTSIDCPGGDLQLAVPADAVPASRAAIPQPRAGRVEPA
>NZ_LT827010|9045686:9090307|9074582_9075086_+|WP_155123730.1|DBSCAN-SWA
MVALTACDSGPANPADTPAAKKDQQMQVMKRTDAENLAKKLAEQVASLVGKPLTGWRTSSAACENTDGVVASDGRWDLSTGGNVEVARDDQVATLNKIRDDWTSRGYQITEFHLLPDGDTGGSTSALVPESGLTISVQSTVPRTGIAIIVVTPCYKPAGNENPARGY
>NZ_LT827010|9045686:9090307|9083770_9084034_+|WP_014695175.1|DBSCAN-SWA
MPHVSGHYRNGRWVRPHYRRSTPRAVRSAGMIRVRGHRRDDGTYVRPHLRNAAPTLTPASSNSDWDWLGYLAMLLFVLFLIGAATQA
>NZ_LT827010|9045686:9090307|9088166_9089333_+|WP_080128165.1|DBSCAN-SWA
MDNGAAGAADGQPERAADGTGAARKAPVKKVAPRSRAAAKAVPAANDQAATGDPAAAETVKRVARPRKAAAGKPPASKMPASGAPEAVKADRTPTTAEADQPATATAPAMTAPAPATTETDQAAATTTPGTAEADRVTDAATPGTAEADQVTDAATPGTAEADQVTDAATPGTAEADRVTDAATPGTAKVYAVGASRTPVVGNAAERLHWAVADQIVVDLWPRLVAEPRDAARILAEAAVQTLGPRAAAWAARTRAAYPAATPQGLARLATAQSVRAAERRGILSALSGTYAPIALVASAALTHADLVLHVAAAYGVDPTDPERAAELVVLLPSYRGGAAWAALRLADRAFPGASMLGAVLGGRNTAEAVAVRAERRYGWYASRRSQE
>NZ_LT827010|9045686:9090307|9049480_9050200_-|WP_014695145.1|DBSCAN-SWA
MPGGRLSQQERHQIALGLADGLAYAEIARRLDRPTSTITREVLRNGGPAGYRADLAQHATERRVRRRRQSAARGPETPASPSGRDDAAIREYEESFTAVLMASGLPRMVARVLTCLYTSDTSPTAADLVGRLQVSKASVSKAVALLESLGLIRRERDKSRRERYVVDDDALYQSMIASARANERLAVTAREGVRLLGPDTLSAARLENIARFADFVGESIVRAAEQARALLSTRPPAAG
>NZ_LT827010|9045686:9090307|9067660_9068125_+|WP_043513162.1|DBSCAN-SWA
MPLIGVLVTLVGYLITNIGRPVPGVRYGVAPVAISHASICGVVALIASPVAPASRGIPAVQKELPPVRCLVPLISARQPALQVDLPLVGLGITPIRRLLPTSEVALAFIQKPPPLRVGRSGVHHLTMERDGLNSTGHRLAGMWTGWAVGFRDRI
>NZ_LT827010|9045686:9090307|9071358_9071739_+|WP_080128163.1|transposase|DBSCAN-SWA
MVDAALTDALARRRPADGLVFHSDRGCQYTSAQHARLAQRHGVRLSVGRRGQCWDNAVAESFFATIKTELIHRQTWPTRKAAHQAIFEYVEGWYNTRRRHSSLGYRSPAAYEGGAAISLLPALKVA
>NZ_LT827010|9045686:9090307|9079942_9083146_-|WP_080128164.1|DBSCAN-SWA
MASLNDVIAVVRQAAQRTLKPSSEFVLRGRVDSDGPRGEGWYRLRARLNPGDLDRMDGACLAPQEGPEQRSFAVIDSEVVDGVLRVRTQSGAPAQGLSFWVPAMDLRASRTAVLEGLSALAPDNLVHRFDQQRLDPLPPAGPCDPRLNDAQQRASDACCAPGLQVVWGPPGTGKTHVIVNAIERLMTAGKRVLLVSNTNVAVDNAVEGIIKRLAPTAGRVIRVGTPRITTVARDERVSLNRLVEARQRTALARLSRLEDTIAELQSNHPQRRLADSEAALAGFDPSEHRRRQARRDNQHRAQQLTAQVQAAALHAAEAKGNLKQATADELLAHLLVAMVYERIARHDRDQAAQGLAEEERSTGLSRAMSTMRRRQARGAAHRAERELDAKRTERTAAEARLRQAGAEVSHALYVQAQAATIAQAHEWAAHAELHQSTAVRVKEAAAEALAAVRQRLSIAAAAAQPSEQDLQLLREAEMRGLPQLHEELSALRQSAVECDRKIRECQTQHDRLVTDLADKRPGMQAALIAEAAVIATTLSMLTLKKMILSTAFDMVIVDEAAAASLPELMFAVKAARTGATLLGDYLQNGPFVDPSLPKEDLIKAVYTRDCFEIFGLTDPATASQQPGCVVLTEQWRFGWELTELANRVAYGGLLTAKNPKTCEIVLVDTDGLGKALSGIRRARPDAVAGTWPIGALIARALAEYHHPRDGSVGIVTPYKEQAETTQELLAESACGPAIEVGTAHTFQGRECDIVVFDMVEDGRGWVAKGAHGSDAWKLQGLRLFNVATTRARQRLYLIGDGAAIRRRGSGPLGALRHMIDAGTIQRVLASDLLGIDEANAPVEETVHHDLWSALQPYIRLVGMYDEKQIIAEVQQRVDSAASSVWMWSPWVGKHSLGLQDSLVAAHARQVEVRVMALPEKEINAEVRATLNALRARLPHVVLVHKMHQKIVVVDLRWTFVGSMNILSHPRRPAEGRHEVMIQIDSARFARQILSFELADQMRNPPRCETCGNTMTEAKEAGRSPDRRWLWYCGRMINGEPCPQTLEFPERTGRNRAGSAPLKRNSTS
>NZ_LT827010|9045686:9090307|9068229_9068583_+|WP_014695162.1|DBSCAN-SWA
MDLQLSARTSGACTVVKVGGEVDTDTVPQLEAFLQQVADGGGVRVVLDLADVSFLDSSGLGALIVWFKELQSRGGRLCVAAVQDLVAYVLRVAAVDQVVNVYDTVEAAEAGMPPSTA
>NZ_LT827010|9045686:9090307|9089533_9090307_-|WP_014695179.1|protease|DBSCAN-SWA
MTLEGQRSTRSAYPAEIAIVLLLSLGQSAIWSIVSLTAKLTDGKPLASHTATLNAPMSPRPYLDLTYQVLNIFFDLVPVALAWYLLRRDGIRPGRDLGIDFRRPGFDAGWGAGLAAGIGLPGLLLVYAAIKLGVSAQIVPSALQPYWWAVPVLVLSAVQNAVLEEVLVVGYLTTRLRQLEVSTGWIVAGSAVLRGSYHLYQGFGGFVGNIVMGVIFAFFYLRTKRVMPLIVAHSILDITAFVGYDLLPDSWLTWLHP
>NZ_LT827010|9045686:9090307|9058062_9058674_+|WP_014695152.1|DBSCAN-SWA
MHRVLTASLIAALGVSLAGSPAEAAALGGSPAQAAKPLDVVKKAVAARIDKRLDALRKDAAALGGAKHLQAAHKQALQQLIDGQSAGLTALKSKVEGETTAAGLKADARSMVVDYRVFMLTGPKVRLSVAIDAELAAADRLHDRPGADDAKLDAVQKSLAGKVDALLAIQPGADGAAVRAQVTTIRTTAKGARSDLKAISGKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014695142.1|9045686_9047549_-|protease	trypsin-like serine protease	A0A1L3KJP6	Hubei_virga-like_virus	5.7e-07	30.0
WP_014695143.1|9048077_9049214_-	flotillin family protein	NA	NA	NA	NA
WP_014695144.1|9049216_9049438_-	hypothetical protein	NA	NA	NA	NA
WP_014695145.1|9049480_9050200_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014695146.1|9050409_9051075_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_052311846.1|9051284_9052889_-	chitinase	M1HUJ4	Acanthocystis_turfacea_Chlorella_virus	1.5e-24	31.4
WP_014695148.1|9053070_9056088_+	EAL domain-containing protein	NA	NA	NA	NA
WP_014695149.1|9056223_9057381_-	Cys-Gln thioester bond-forming surface protein	NA	NA	NA	NA
WP_014695151.1|9057862_9058054_+	hypothetical protein	NA	NA	NA	NA
WP_014695152.1|9058062_9058674_+	hypothetical protein	NA	NA	NA	NA
WP_014695153.1|9058657_9059932_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	3.2e-126	57.7
WP_014695154.1|9060052_9060934_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_043513155.1|9061161_9061365_+	hypothetical protein	NA	NA	NA	NA
WP_043513158.1|9061964_9062198_-	hypothetical protein	NA	NA	NA	NA
WP_014695158.1|9062203_9063061_-	hypothetical protein	NA	NA	NA	NA
WP_014695160.1|9065337_9067194_+	response regulator	NA	NA	NA	NA
WP_043513162.1|9067660_9068125_+	hypothetical protein	NA	NA	NA	NA
WP_014695162.1|9068229_9068583_+	STAS domain-containing protein	NA	NA	NA	NA
WP_014695163.1|9069429_9069591_+|transposase	IS3 family transposase	NA	NA	NA	NA
WP_099343963.1|9069648_9070227_+|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.3e-13	33.1
WP_014691959.1|9070223_9071222_-|transposase	IS481 family transposase	NA	NA	NA	NA
WP_080128163.1|9071358_9071739_+|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	4.5e-20	41.5
WP_014695167.1|9072579_9072885_+	hypothetical protein	NA	NA	NA	NA
WP_155123729.1|9072891_9074544_+	hypothetical protein	NA	NA	NA	NA
WP_155123730.1|9074582_9075086_+	hypothetical protein	NA	NA	NA	NA
WP_014695171.1|9076263_9076821_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014695172.1|9078079_9079171_+	methyltransferase domain-containing protein	A0A1J0MC50	Streptomyces_phage	2.3e-16	38.6
WP_080128164.1|9079942_9083146_-	AAA family ATPase	NA	NA	NA	NA
WP_014695175.1|9083770_9084034_+	hypothetical protein	NA	NA	NA	NA
WP_099344252.1|9084366_9087030_-	AAA family ATPase	NA	NA	NA	NA
WP_080128165.1|9088166_9089333_+	hypothetical protein	NA	NA	NA	NA
WP_014695179.1|9089533_9090307_-|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA