CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT632322	Murdochiella vaginalis strain Marseille-P2341T chromosome contig00001	10 crisprs	RT,csa3,cas3,DEDDh,cas4	5	1	2	0

1. NZ_LT632322

CRISPR-Cas detection and classification

Crispr_ID: NZ_LT632322_1

• CRISPR_ID: NZ_LT632322_1
• CRISPR_location: 250976-251244
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_LT632322_1

Consensus_repeat	Method
AAAATGTTTCATGTGAAACATTTT	PILER-CR
AAAATGTTTCATGTGAAACATTTT	CRISPRCasFinder

spacers of NZ_LT632322_1

>1.1|251000|49|NZ_LT632322|PILER-CR,CRISPRCasFinder
GGGGTGGCTTTTTTGCACACAAAAATTTCGCATATAGCATATAAATGAA
>1.2|251073|46|NZ_LT632322|PILER-CR,CRISPRCasFinder
AAGCTGAAACAGGAGAGCGAGGTCACGGGGCAACAACTTTCGTTTC
>1.3|251143|78|NZ_LT632322|PILER-CR
GAAACACATAGTCATTAATATGATATGCCCTTAGGAAGTTCCTTTGCTATAATTGTTGCAGGCAGAATGGCCACGGAA

CRISPR arrays and Neighbor proteins around NZ_LT632322_1

CRISPR arrays

The CRISPR arrays of NZ_LT632322_1

>merge|NZ_LT632322|1|250976-251244|PILER-CR,CRISPRCasFinder
AAAATGTTTCACGTGAAACATTTTGGGGTGGCTTTTTTGCACACAAAAATTTCGCATATAGCATATAAATGAAAAAATGTTTCATGTGAAACATTTTAAGCTGAAACAGGAGAGCGAGGTCACGGGGCAACAACTTTCGTTTCAAAATGTTTCATGTGAAACATTTTGAAACACATAGTCATTAATATGATATGCCCTTAGGAAGTTCCTTTGCTATAATTGTTGCAGGCAGAATGGCCACGGAAAAATTGTTTCATGTGAAACATTTT

>NZ_LT632322|1|1|250976-251244|PILER-CR
AAAATGTTTCACGTGAAACATTTT	GGGGTGGCTTTTTTGCACACAAAAATTTCGCATATAGCATATAAATGAA
AAAATGTTTCATGTGAAACATTTT	AAGCTGAAACAGGAGAGCGAGGTCACGGGGCAACAACTTTCGTTTC
AAAATGTTTCATGTGAAACATTTT	GAAACACATAGTCATTAATATGATATGCCCTTAGGAAGTTCCTTTGCTATAATTGTTGCAGGCAGAATGGCCACGGAA
AAATTGTTTCATGTGAAACATTTT

>NZ_LT632322|1|1|250976-251142|CRISPRCasFinder
AAAATGTTTCACGTGAAACATTTT	GGGGTGGCTTTTTTGCACACAAAAATTTCGCATATAGCATATAAATGAA
AAAATGTTTCATGTGAAACATTTT	AAGCTGAAACAGGAGAGCGAGGTCACGGGGCAACAACTTTCGTTTC
AAAATGTTTCATGTGAAACATTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071704973.1|251255_252497_+|CinA-family-nicotinamide-mononucleotide-deamidase-related-protein	unknown	unknown	gnl|CDD|234789
NZ_LT632322.1|WP_071704968.1|244692_244908_+|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl|CDD|376620
NZ_LT632322.1|WP_071704972.1|250219_250948_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl|CDD|234637
NZ_LT632322.1|WP_071704967.1|244213_244696_+|ribonuclease-P-protein-component	unknown	unknown	gnl|CDD|376392
NZ_LT632322.1|WP_071706039.1|259768_260692_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223566
NZ_LT632322.1|WP_071706038.1|255675_256653_+|phosphate-acetyltransferase	unknown	unknown	gnl|CDD|236609
NZ_LT632322.1|WP_071704966.1|242059_243523_-|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl|CDD|273037
NZ_LT632322.1|WP_071704976.1|254414_255554_+|DUF4446-family-protein	unknown	unknown	gnl|CDD|379655
NZ_LT632322.1|WP_071704969.1|245745_246849_+|Jag-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|224760
NZ_LT632322.1|WP_071704977.1|256733_258188_-|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|236426
NZ_LT632322.1|WP_071704965.1|240783_241893_-|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl|CDD|235541
NZ_LT632322.1|WP_071704980.1|259446_259755_+|thioredoxin-fold-domain-containing-protein	unknown	unknown	gnl|CDD|239245
NZ_LT632322.1|WP_071704975.1|253284_254403_+|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl|CDD|275105
NZ_LT632322.1|WP_071704974.1|252484_253282_+|ParA-family-protein	unknown	unknown	gnl|CDD|379293
NZ_LT632322.1|WP_083428132.1|245008_245746_+|YidC/Oxa1-family-membrane-protein-insertase	unknown	unknown	gnl|CDD|376730
NZ_LT632322.1|WP_071704970.1|246885_248307_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl|CDD|235392
NZ_LT632322.1|WP_066925356.1|244018_244153_+|50S-ribosomal-protein-L34	unknown	unknown	gnl|CDD|366117
NZ_LT632322.1|WP_071704971.1|248316_250218_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl|CDD|235362
NZ_LT632322.1|WP_071704979.1|259121_259460_+|DUF1622-domain-containing-protein	unknown	unknown	gnl|CDD|377914
NZ_LT632322.1|WP_071704978.1|258328_258994_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|223620

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071704973.1|251255_252497_+|CinA-family-nicotinamide-mononucleotide-deamidase-related-protein	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	1.18184e-131
NZ_LT632322.1|WP_071704968.1|244692_244908_+|membrane-protein-insertion-efficiency-factor-YidD	gnl|CDD|376620	pfam01809, Haemolytic, Haemolytic domain. This domain has haemolytic activity. It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.	1.30293e-29
NZ_LT632322.1|WP_071704972.1|250219_250948_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl|CDD|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	1.43635e-74
NZ_LT632322.1|WP_071704967.1|244213_244696_+|ribonuclease-P-protein-component	gnl|CDD|376392	pfam00825, Ribonuclease_P, Ribonuclease P.	2.42938e-34
NZ_LT632322.1|WP_071706039.1|259768_260692_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	2.55846e-53
NZ_LT632322.1|WP_071706038.1|255675_256653_+|phosphate-acetyltransferase	gnl|CDD|236609	PRK09653, eutD, phosphotransacetylase.	7.78474e-174
NZ_LT632322.1|WP_071704966.1|242059_243523_-|chromosomal-replication-initiator-protein-DnaA	gnl|CDD|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LT632322.1|WP_071704976.1|254414_255554_+|DUF4446-family-protein	gnl|CDD|379655	pfam14584, DUF4446, Protein of unknown function (DUF4446). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 165 and 176 amino acids in length.	1.24489e-27
NZ_LT632322.1|WP_071704969.1|245745_246849_+|Jag-N-terminal-domain-containing-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	8.61269e-40
NZ_LT632322.1|WP_071704977.1|256733_258188_-|nicotinate-phosphoribosyltransferase	gnl|CDD|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_LT632322.1|WP_071704965.1|240783_241893_-|DNA-polymerase-III-subunit-beta	gnl|CDD|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	7.33934e-106
NZ_LT632322.1|WP_071704980.1|259446_259755_+|thioredoxin-fold-domain-containing-protein	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	4.06972e-32
NZ_LT632322.1|WP_071704975.1|253284_254403_+|ParB/RepB/Spo0J-family-partition-protein	gnl|CDD|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.36142e-62
NZ_LT632322.1|WP_071704974.1|252484_253282_+|ParA-family-protein	gnl|CDD|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.07501e-83
NZ_LT632322.1|WP_083428132.1|245008_245746_+|YidC/Oxa1-family-membrane-protein-insertase	gnl|CDD|376730	pfam02096, 60KD_IMP, 60Kd inner membrane protein.	4.0856e-47
NZ_LT632322.1|WP_071704970.1|246885_248307_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl|CDD|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_LT632322.1|WP_066925356.1|244018_244153_+|50S-ribosomal-protein-L34	gnl|CDD|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	1.71342e-09
NZ_LT632322.1|WP_071704971.1|248316_250218_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl|CDD|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NZ_LT632322.1|WP_071704979.1|259121_259460_+|DUF1622-domain-containing-protein	gnl|CDD|377914	pfam07784, DUF1622, Protein of unknown function (DUF1622). This is a family of 14 highly conserved sequences, from hypothetical proteins expressed by both bacterial and archaeal species.	3.3898e-09
NZ_LT632322.1|WP_071704978.1|258328_258994_+|HAD-family-hydrolase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	5.83558e-46

Protein sequences

>NZ_LT632322.1|WP_071704972.1|250219_250948_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MYDQKSGLQERAIKLGFTLTELQCRQFEEYRSLLLAWNNKMDLTAITEAAEIDNKHFLDSLSILRFFPEGISGRVVDIGTGAGFPSIPLKILNPTMSLTLVDSLNKRILFLKEVVHTLELADVSLFHTRAEDFLQASPENAHRESYDYVVARAVAPLPTLLEYTLPALRIGGELIAMKGPGARQEVEDAKNALAELGGEVIEIDEFTWTEQQYQRVNLRIRKERPTPNRYPRGKGKAKKRPL
>NZ_LT632322.1|WP_071704971.1|248316_250218_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MDKKYYKRKTVDVVVIGAGHAGCEAALASARLGMETVMLTISLDSVGDMPCNPNVGGTGKGHLVREVDALGGEMARVIDETFLQSRMLNTSKGPAIHSLRVQADKRRYHECMKKRLEDQPHLQLIEGEAVELVIEDGQVRGVGTLQGAFYEAQAVIICTGTFLNGTILMGDVSYSSGPHGLRPSLYFSDALRKAGIPLKRFKTGTPARVNRRSIDYSRLVVQDGDPEIVPFSFLNQDKSYDATNQMPCYLTYTTDETKRIIEENLHRSPMYSGEKHGVGPRYCPSLEDKMVRFADHPQHQIFLEPEGRDTEEVYVQGASTTLPEEVQMAFYRTITGLEHVEIMRSAYGIEYDCIDARALKSSLEARSCKGLFFAGQVNGSSGYEEAAAQGLMAGINAARLLTNKDPLVLDRSQAYIGVLIDDLVTKGTNEPYRMMTSRCEYRLSLRQNNADLRLTGIGHTIGLASEERYKRMKAKWERIAKEEERLKTRMVTPTEETNAFLIAQSSSPLKTGVTLAELLRRPELTYASLSPLDPDREKLPKEIRMEVETQIKYEGYIAKQNAQIAQFRKLEGRKLDTMDYTLVSGLKKEAAEKLNAVQPESIGQASRISGVSPADMNVLLIYLEMKRRKEKES
>NZ_LT632322.1|WP_071704970.1|246885_248307_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MTKTTSTTAIGNFREDTIAAISTSLGPSGIGIVRLSGPDAFSIVHRLFQPAENKPFSPAQYRRLRYGWIVENGERIDEVLVSCMPGPHTYTAEDVAEINTHGGAISVKRVLACVLRCGARLADAGEFTRRAFLNGRIDLAQAEAVMDIIDAKTEQAQTQALQQLSGELSSEINALKESMLHLLSHVEYAINFMEDAQEELPTKPMLEEAEAILQRMDALLQDANSGRLIREGIATVIAGRPNVGKSSLLNALLRRERAIVTDIPGTTRDAIEESYILDGVCLRLIDTAGIRDTEDTVESIGVTISRSQVAQADLILAMLDGSRPFSKDEESFLQEVADKPVIILLNKQDLPLSPSMQSARDRWQDEKPDIPWIALSAKEKTGLDRLKDAILERIFHGAAPKQPAMLSNMRHIDRLTKAKEALEEARRALASGVVLDALEVDLRDSYNRLADITGERAGEDVLDRIFHDFCVGK
>NZ_LT632322.1|WP_071704969.1|245745_246849_+|Jag-N-terminal-domain-containing-protein
MQSIVKTGKTVDEAVQAALQALDATLDDVSIEIMEEAKSGFLGVFGTKEAIVRVSRKESTLHDVLHEKKPAKPVAKKEQNDKTASASAALNTAETKPEAEKVVSKAPEAKVEVAETKAEEPDTEAEAKGSKAEVPSSLPQEDAVAEKPAHSLLDRIHEEVEREQSKQEISLVGADKESSASQKAPSAESASTEEAASAESTSVKKSTTPTRELDNVEIIRFSENWLSSILEEMHITAQLNFFIEEENLRVEMTDISETDMGIVIGRRAETLNAIQYLLGVTLNRISKRHYRVYLDVGDYRKRRAQNITRLAERNAEKVRRSKRSVKLEPMNAYERRIVHTALQDMEHIETVSEGREPHRKVVILYKE
>NZ_LT632322.1|WP_083428132.1|245008_245746_+|YidC/Oxa1-family-membrane-protein-insertase
MQNIFSPLSDIFGWMMGQIYHFLANSFAEPARMSYFAITILVMAVISKLITIPLMAQTTKSSAKMQALGPKTEELKRKYGYDERILQQKTQELYKEEGVSMMGCSSCLPMLIQLTLIIALFNVLREPAKYMASSLDNFSAISKNFFWISDLLKSDPLTWFGLPLLNAISQLGIQLFGPMRQQQQMNKNMNITFMLMPVMFYFLSVNWAAGLLLYWVFGNLLELLYRGIAALINRSKLHSATEGGK
>NZ_LT632322.1|WP_071704968.1|244692_244908_+|membrane-protein-insertion-efficiency-factor-YidD
MNRIAYFLIRGYQRFLSPLLGRGKCRFHPTCSHYALEAFTRFRFSTALMLTLWRILRCNPFQKGGEDPLLP
>NZ_LT632322.1|WP_071704967.1|244213_244696_+|ribonuclease-P-protein-component
MKRSFRLRKNDEFQRVYRRGIPAYDRDFKIIGFRNHLGHNRYGFSLSKKFGKAHERNRTKRRLREIVRAHEQTFPQSFDYVILPKPSAKTCTFQQLEQSLLHCLAQWKKRMETKTKRSETPTQRNMPSSQTKAENNTTESTANAAFHAVADSVVKESHLL
>NZ_LT632322.1|WP_066925356.1|244018_244153_+|50S-ribosomal-protein-L34
MKRTYQPNKHKRKKDHGFRARMSTKTGRRVLKARRLKGRKRLSA
>NZ_LT632322.1|WP_071704966.1|242059_243523_-|chromosomal-replication-initiator-protein-DnaA
MNDLTMIWNEVLSMLDIQLNRIQLKNWLQPLIPVALHENTFVLDGTSAFIHSMVEKKYKSDIERCLSYICEKAIRVELIDPSMPDYEQRLLGAEKEGRTIEEDVVSSTPEEATAYENPQEISRKLREKNDFLEQQHRRNGYNTLNPKYTMESFVRGASNDFAYATAIAVIRAPGKVYNPLFIYGLSGLGKTHLMQAIAHEILQTDPQKKVLYITSENFMNEMIAVIENGTNAEKENFRHKYRSIDVLLIDDIQFIAGKKATMEEVFHTFNDLKEAGKQIVLSADKPPKELKNLEDRLVTRFEGGMTVDIQQPDFETRVAILNHKMKGESIKLPQYILEFIANNITANIRELEGALLRVLAYYRFKEGSEELSKEEAMAIAREALKIEEYTESKLSVEEIIRRVCEYYNLSLHDMTSKSRQGSIVLPRQVAMYLCRELTNESLVAIGRGFSRDHTTIMHAVDKIRARMEKEPSLKEDINSLVTQLTHT
>NZ_LT632322.1|WP_071704965.1|240783_241893_-|DNA-polymerase-III-subunit-beta
MKIQVLPSELVKLIGQCQRAISTRTTMPILECIRFEAYGETLTLTATDLELTIQTSMPCKVLEEGVMVAASAMIGNIFRKLPGAMATVEENRGVLKIRCAESHFDLQVPSASDFPEVPEVNSERMTVIANDVLAQAITETEFATSLDESKIALTGIFYERRPENVRLVTLDGYRLAVRDIALDAHQEVFEESMIVPKRCMIELSRLLQPEENTVIRSVPGHIYFESGLLKLYSRLIDKNFINYEEIISDEKKSTVIVDRQAFRDAIERASLLTQGERAHLIKLDFQEEGLHIESNSELGHVDEFVDVDCKGENCCIAFNAKYLLDGVRALQSERITLALNGTLNPMIIRPTEEEESYLYLVLPVRIAGQ
>NZ_LT632322.1|WP_071704973.1|251255_252497_+|CinA-family-nicotinamide-mononucleotide-deamidase-related-protein
MIVECISVGTEILLGDILNTNVQYLSRLCAEVGLDVFHTSVVGDNVERLKQALQLACSRSDAVILTGGLGSTDDDITKRVVIDFLHQGTQVSTYNKSTIETWFDNEKARKDNEIVYTFPKGSTILKNHVGTASGAVIPFNQGEKQGYIVILPGPPKEMIPMVEKELRPILYKWSDSVTESLVVRFGILGEYRINEILKEEIVNGINPTIAPYVKEDGALIRITAKAPTDIEAKERIEKAYLQVEKKLGKYIVAVGEESRSEVLVRILKERKEHVSTAESITGGLVASTIIEAPGASNVLEESFVVYSDRAKHTILGVPNNKLEKHTAVSQSVCRSMLKGLHEKTKSDLCIATTGYAGPEGEDVGLCYVGIRYHGKKRVFQHDLHGDRNHIRNRAKNLAVDYAIMMMKGELWEE
>NZ_LT632322.1|WP_071704974.1|252484_253282_+|ParA-family-protein
MGRIISIYNQKGGVGKTTTVVNLAAALALTGLFKKKVLVIDLDPQGNTTSGFGLEKNTESPDVYSVMLEEATLAESWKSVRKETLKVVPSTADLTGFEIESAAMPDAHQRLKKALIPVAAQFDYILIDCPPSLGMLSMNALVASDSVLIPIQTEFYALEGVSQLVKTLSLVRASLNPTLEVEGVLLTMYDARTNLAQDVRAEVNHYFEGKVFETEIPRNVRLAEAPSFGESAVTYDKYSKGAQAYIKLSKEIKRKHGKDPVEDKE
>NZ_LT632322.1|WP_071704975.1|253284_254403_+|ParB/RepB/Spo0J-family-partition-protein
MARKRGLGRGLGALIPNSKQEKKPTIDTKKPTDEKKTVQPEPKKTAAKPSKNTTTVAKPETKAAASAKAATKAGKTSQSAGKASSTSKTANTAKTSANSTKRKAKEESKLSATETVLRSMQHLALDQIEPNPDQPRKNFEEASLAELTESIRTYGVLQPIVVEKYTAPGHAPYRIIAGERRYRAASHAGLKEIPVVLREDRPEEQMLLSVVENVQRQDLSPVEEAVAYQHIMEERHMTQQELSVALGKSRPYIANAVRLLRLDEASLEALREGKLTSSQARTLLAEKDLKKRAAYLKLLTEGRASVQEVENRRKKPKTTDAFLVDVERRFSEALETPVAVISRRKGWSVQIACYNEEDLNRLLERFSASDQH
>NZ_LT632322.1|WP_071704976.1|254414_255554_+|DUF4446-family-protein
MPNFLMPALLFVVFVLMIGCFYIAGNTNNKLNRMRRRYDLLLRGRSDINMEELLLSLSGELDASKEERAKAEQKIYHIEQWIARTDADQTAHVDERFATISRQLTEEMRQSTSSVMQTINRVDSEVKERMNAVEKESAESIIREASALRAQLNEFSQATVRQVKKNEEDAFVRFDSIEKNAAAWKEEIDSRLLNMETDANGRFRQLEGGLVERIAGLQTITQNRFQNMEQKAQETFAAGRAETEQWLKTLEQNTNARAEQMEKDLHHRVDTLQQETNERVSNFEKETTQKVKSESLRLREQLAMAIQKIYVHRYNAFADVAGESSFSAVLLDEYRNGLILTTIYSRENTITFAKEVRSGEPVQKLSPEEEHALDEAMKR
>NZ_LT632322.1|WP_071706038.1|255675_256653_+|phosphate-acetyltransferase
MTIVQEAAQAIKGKNIRIVYPEGTDARILHAAVRHAKDGIIHPILLGRRERVEELAKQEGVSLEGLEFIDYLNYDHYDEMLAQLLERRKGKIDETKAHSMLKDRNYFGTMLVYMGKADGLVSGADGPTGDTIRPALQIIKTKPDAKLVSGCFIMISPDEKERLLFADSAVNISPSEEELADIAYQTAQTAKLFNIEPNVAMLSFSTYGSASSPEQERMANATAVAKKKYPDLNVDGEMQLDAAWNETVAKKKAPGSTVAGKARVFIFPDLQSGNIGYKIAQRLGNYTALGPLLQGMARPVNDLSRGCSEQDAYEIGIITAFQAMY
>NZ_LT632322.1|WP_071704977.1|256733_258188_-|nicotinate-phosphoribosyltransferase
MKRSQENLAMLFDFYEMTMANGYFERGLKDTIGYFDLYYRENPDQAGFAVFSGLESVIEYLRNLHFREEDIAFLRSKNIFSDAFLDYLKDMRFSCDVWSVPDGSVVFPNEPLITVRGPMIQTSLIETMLLLLVNHQSLIATKASRIVRAANGRPVMEFGSRRAQGPDAATLGARAAYIAGCVGTADTLSDQRFGVPALGTMAHSWVQLFPSEYEAFKAYAEIYPTNATLLVDTYDTLSSGVPNAIRVFDEVLKPKGLSGGIRLDSGDIAYLSKKARIMLDESGHPEAKIVASNSLDEYRIEDILAQGAKIDSFGVGENLITSKSAPVFGGVYKLVGMEKDGIFEPRIKISENVEKITTPGFKTIHRLYDKATGKALADVITMKEEKIDDQKPYELFHPVYTWKRMTLESFVAREMKERIFSDGRLVYDLPTLEERRDYCAKELDTLWEEYKRFDNPHEYKVDLSLAVWDMKHDLLARTQQRIRP
>NZ_LT632322.1|WP_071704978.1|258328_258994_+|HAD-family-hydrolase
MKTVILFDLDGTLLYTLPSITAAMNRTLQRFGLREISLERVRELVGNSSRYLVEHATQESGASGWTYEQTEHFLDAYNADYLAHPIEGTTPYPGTEALLDALKKQGKQIWVYSNKPDAIVHEVVKHFFGDRFDCLRGYREDTPRKPDPAGVYAMLKESGKQVTDVLYVGDSEVDWKMAQAAGLDMLLLSYGFRTEEELRQTTTATSFIATPEALERALLES
>NZ_LT632322.1|WP_071704979.1|259121_259460_+|DUF1622-domain-containing-protein
MSWFHPLLEYTVFGVELIAYVVIATSLVRCLYEVIVVDRCNIRKFHDHETLPDGVAAALEFLMAAEVLKTMVAFQLKDMLLLSMLIALRVFLSYVLRRRRLEKKEGDQNEKN
>NZ_LT632322.1|WP_071704980.1|259446_259755_+|thioredoxin-fold-domain-containing-protein
MKKIDAQEFRTLVLERKGVCLVDFTATWCGPCQMLAPVLEEISAAGHTVYTVDVDEEGPLAMEYRVSGVPTMVFFKDGEKKEQLVGLTPKQTILDKLAYYEN
>NZ_LT632322.1|WP_071706039.1|259768_260692_+|NAD(P)/FAD-dependent-oxidoreductase
MGVPVSKTNNERAGSPEQALYDVAVVGSGPAGLSAALNAAIRQKSVVLFGASRSERLLQTESVENYLGLPGESGETLLDKFLAHVRQYPDIVRRQENVQIIYDMGEAIGLLLAENEIIRARSVILATGVNFGTPLPGEEKFLGKGVGYCATCDAALYKDRPVVVVGYNEEAITEVNFIAEMASSVVFVNCTGREYSLAKGVQEIRQKPLEILGDDRARALRLEEEVLEADGFFLLRDARAADALVPGIALEGRHVAVDRNMATNLPGIFAAGDLVGTPYQINVACGRGQIAGLAAARYATMRSASVK

Crispr_ID: NZ_LT632322_2

• CRISPR_ID: NZ_LT632322_2
• CRISPR_location: 358112-358368
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_LT632322_2

Consensus_repeat	Method
NGAAAACGCNTTTCCACCACCATCGTTTNTGCCTTCGG	CRT

spacers of NZ_LT632322_2

>2.1|358149|18|NZ_LT632322|CRT
CGATGGTGGGGATTTAGT
>2.2|358204|18|NZ_LT632322|CRT
TGATGGTGGGGATTTAGC
>2.3|358259|18|NZ_LT632322|CRT
CGATGGTGGTAGTAGGGC
>2.4|358314|18|NZ_LT632322|CRT
TGATGGTGGGGATTTAGC

CRISPR arrays and Neighbor proteins around NZ_LT632322_2

CRISPR arrays

The CRISPR arrays of NZ_LT632322_2

>merge|NZ_LT632322|2|358112-358368|CRT
CGAAAACGCGTTTCCGCCACCATCGTTTTGCCCTTGGCGATGGTGGGGATTTAGTGAAAACGCATTTCCACCACCATCGTTTATGCCTTCGGTGATGGTGGGGATTTAGCGAAAACGCATTTCCACCACCATCGTTTGTGCCTTCGGCGATGGTGGTAGTAGGGCGAAAACGCATTTCCACCACCATCGTTTATGCCTTCGGTGATGGTGGGGATTTAGCGAAAACGCGTTACCACCACCATCGTTCATGCTTTCGG

>NZ_LT632322|2|1|358112-358368|CRT
CGAAAACGCGTTTCCGCCACCATCGTTTTGCCCTTGG	CGATGGTGGGGATTTAGT
GAAAACGCATTTCCACCACCATCGTTTATGCCTTCGG	TGATGGTGGGGATTTAGC
GAAAACGCATTTCCACCACCATCGTTTGTGCCTTCGG	CGATGGTGGTAGTAGGGC
GAAAACGCATTTCCACCACCATCGTTTATGCCTTCGG	TGATGGTGGGGATTTAGC
GAAAACGCGTTACCACCACCATCGTTCATGCTTTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705031.1|348035_349751_+|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl|CDD|225174
NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein	unknown	unknown	gnl|CDD|377856
NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|376487
NZ_LT632322.1|WP_147659357.1|343708_343954_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705029.1|344082_346905_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237259
NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein	unknown	unknown	gnl|CDD|377851
NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein	unknown	unknown	gnl|CDD|380155
NZ_LT632322.1|WP_097677427.1|350860_351541_-|YitT-family-protein	unknown	unknown	gnl|CDD|376838
NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NZ_LT632322.1|WP_071705035.1|353417_353957_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein	unknown	unknown	gnl|CDD|238206
NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase	unknown	unknown	gnl|CDD|130918
NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl|CDD|340853
NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239241
NZ_LT632322.1|WP_071705032.1|349888_350692_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_147659358.1|352606_353005_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_097677415.1|346914_348034_+|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705031.1|348035_349751_+|proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein	gnl|CDD|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	1.34831e-05
NZ_LT632322.1|WP_097677415.1|346914_348034_+|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31	gnl|CDD|376487	pfam01197, Ribosomal_L31, Ribosomal protein L31.	2.41268e-37
NZ_LT632322.1|WP_071705029.1|344082_346905_+|preprotein-translocase-subunit-SecA	gnl|CDD|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein	gnl|CDD|377851	pfam07501, G5, G5 domain. This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.	8.72897e-14
NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein	gnl|CDD|380155	NF012221, MARTX_Nterm, MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA. This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.	0.00297151
NZ_LT632322.1|WP_097677427.1|350860_351541_-|YitT-family-protein	gnl|CDD|376838	pfam02588, YitT_membrane, Uncharacterized 5xTM membrane BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C).	1.08443e-28
NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	7.315e-90
NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein	gnl|CDD|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	6.74256e-44
NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	5.17142e-82
NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase	gnl|CDD|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl|CDD|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	2.19914e-94
NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase	gnl|CDD|130918	TIGR01859, Fructose-bisphosphate_aldolase, fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis].	5.57911e-139
NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase	gnl|CDD|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	2.46718e-123

Protein sequences

>NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase
MATTTKQPHPAQHTAENPALPEALAPLFTPWKIGTVEIKNRIVLTSMGGTNLLGWMEKNHFDETGAHFIRTIAENNVGLVLPGCQPVYNPMFGQWLYKNKRMYDDLAKWLPAFHQTGAKLFVQLTAGFGRSFTISPMMETLYTNPVLRFLSKPVMNLDKITASASEAPNRWSDKVPSRAMTVAEIQQMVEAFGKSAKLLKDAGVDGVEVHAVHEGYLLDQFTLKYVNHRTDAYGGSRENRYRFPVDIVREIKRVCGENFPVSLRYSVESKTKGFRQGALPGEEYTEVGRDMEESRWAARYLQDAGYDMLNCDNGTYDAWYWCHPPIYMPENCNLDEVKEIKKAVTIPVVPAGRMDPYVGAKEVAAGTIDGVGFARAFLADPEWVTKILEGRSEEIRPCICCHNACFNMSKWKGTPNMQELQDSLHLARCAVNAETMQWDKHYIKKTDAPKTVHIIGGGVGGMEAARVLKLRGHNPVIYEQTDRLGGVVIPGAAESYKKPMRDLLAWYRQEMERLDIPVHMNQSIAPDHDFGTDPVIVATGGKPISLSRVPGFDRTIEATDFLRALEGRREEEGVAVKKGVGRRVAVIGGSLTGCEIAYELALQGKEPFILEMKEDLIATEGVCLANSSYLREWFALHKVPVYLESTLVEVKEDAVTYKDASGALHEVPCDSVISAVGYRPDPLLDKAHTGAQTYFIGDCAGIGNIKTAVWQAYETAMKI
>NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein
MDEQERLEQTEEWNEDARKAQSPHYEEAATRRIVREEIARNYRPKGSAARAVALVLCGALLGAGGGAALVASGNIPLPQQQEQAASATTNGNINISLKEGQTTVENAIAAKTIPSIVGITTIAKSVSNNPFLYGTPQYSESVGSGVIVSADGYILTNAHVVNGGNAKTVRVRLSNGEEAEAKVLWADPTLDLAVIKVEKKNLPAITFGDASKVQVGDKAVAIGNPLGLDLQSTLTSGYISGLNRSITLQDGNIMDGLIQTDAAINGGNSGGALLNAKGELIGINTAKPASADGIGFAIPVSTVKPIVDKIVADGTYTPLYMGINGANTKLVAASGVEGLPTDSGVVVRDVVAGSPAATMGIEPYDIIVAINNEPVESMNTLKTLLLKYKKGDTVDVTYYHGRDKKTGKMTFTDFSPEAIQR
>NZ_LT632322.1|WP_071705035.1|353417_353957_+|hypothetical-protein
MQRTTKQPRRRWMQIAASIPNREKEEERRQDLERFHAKVGDEKEWIVMRLDDVDALIEQLTRETETIRESLDRPHHERVSSLAPLTEAGKQHLSRKRLLRSSAELDVLLLEVHRHPVFRDIVADMQNLTVPETTLPVENESSVVASRKMLSIRDQLSDLLDNLYRLRRRLRRELLRLAR
>NZ_LT632322.1|WP_147659358.1|352606_353005_-|hypothetical-protein
MSQNVLPPPSLTASVMVGVCVKWAFTTITCDFGDGGDLPKSRFHHHHLRLRRWWWFAKIALPPPSLAASAMVVVCQNRASTTITCDFGDGGDLPKSRFHHHHLRLWRWWWFAKIALPPPSLAASAMVVVCRK
>NZ_LT632322.1|WP_097677427.1|350860_351541_-|YitT-family-protein
MQLLRRFAAWMNISVLDLFLMVLGNLTMAFAIYNIHVPSRITEGGVLGSIVLLNKVFGLDPAILSIVLDFSLYGLGILLLERGFLKKAVFSTLAYAGSWTLFAAIGPVLPSLANAPHLAAIVGGLLLGAGCGLVVTRGGAAGGDDCFALILKKRTSLSLSSAYFISDAVVLGLSFFIYLPAQNLLWSFLTTLISSFVVGQFELRLPKPGTLAMPMKQQADASNMSA
>NZ_LT632322.1|WP_071705032.1|349888_350692_-|hypothetical-protein
MKRRFFIVLLLLFLLCPSLSHADMGPKPYVSVHIAGSDTRYYATLLSSSAEYGPWRANAVWTTDAPDSIQQKFQQFSLPEDHYFLGYVAEAAPRDFCWSYYPPETFRILLYDEKADHFLMSAPLTRHALKNEYTVTIKEDRITDIHFHYDYLADVPKLLALIAGTILIELAVAYLMGIRETASLRYIALVNLGTQALLHLGLWFIGFRLGTTGIMPVMRPVLLLPLEALVLGIEALLYRRKLPKEQHPVRYAILANLVSYTVSLLIP
>NZ_LT632322.1|WP_071705031.1|348035_349751_+|proline--tRNA-ligase
MRMKRFYMPTLREVPGDAEVPSHQLLLRAGMIRKAASGIYTYLPLGYRVVRKIEEVVREEMDRAGAQEIRVSNLQPKEIWEASGRWDTFGPEMFKLTDRHEKEFALGPTAEEYFTDLVKEELRSYKQLPLNLYQIGWKYRDEKRPRFGINRSCEFLMKDAYTFDIDQEGLEAAYQVMWDAYVRVFDRLGINYRVVQGDSGAMGGHVSHEFTALSEIGEGVIVYAEGGYAATDEKASMQKPTYPAEEPLPVETLDTPNAHTIEELEDFLHIPAHKMIKAICLRISGEPVFVFMPAERELNMSKLIAYLHTPEHEIEMLDDETIERVTGAPAGFTGPVGLPDTVRTIFDAAVTTRENLVCGANKADTHLKNVNFGRDFDGEIAEDLWMVAEGDLDPIHGNPLQFARGIEVGNIFQLGTKYSEALGATVLDENGVARPLVMGSYGIGVTRVVSAIIEQNHDEKGMIWPLIAAPYHVMITVMKTNDETQMQLADALYERLEKEGVEVLLDDRDERPGVKFNDRDLIGIPLRITVGRNAAAGMVEYSTRREMTNEDVSVEEAVSRVAAAMETLREV
>NZ_LT632322.1|WP_097677415.1|346914_348034_+|peptide-chain-release-factor-2
MELYEMRQHLETVRVHLSELRSSLDIAGLEESVKALSEKTTDPDFWNDSDAAQSVMVELNGKKANIDAYQEIEAAYEDLNGLVELFDEDEYQAEKDDLTDALEQIEKKLGALSKKALLSGEYDANDCYLSIHAGTGGTEAMDWAGMLMRMYERWFQTKDWKVTLTDINTEEMGGIKSVQFEIKGYDAYGYCKGEKGVHRLVRISPFDSQSRRHTSFASVDVYPVLKDIGEIQIDEKDIKVDTYRSTGAGGQHVNTTDSAIRITHLPTGVVVTCQNERSQIQNRAKAMEMLIAKLVQIKEEEHREKIADIQGSYKQIAWGSQIRSYVFQPYTLVKDHRTGEETGNIEKVMDGDLDPFVDAYLNWHAQQEAKGE
>NZ_LT632322.1|WP_071705029.1|344082_346905_+|preprotein-translocase-subunit-SecA
MGLFGFLTKSFSEKEIDKIRPQVDAVLALEPEMAKLSDSELRAKTEEYKKRYQDGETLDALLPEAFATVREAAWRVLGMKPYPVQVIGGIILHQGRIAEMKTGEGKTLVATMPAYLNALAGEGVHIVTVNDYLAQRDAEWMGKVHQFLGLTVGVVLQPMEQAERQHAYNADITYGTNNQFGFDYLRDNMAIYKSGVVQRKLHYAIVDEVDSILIDEARTPLIISGMGDPSTEMYSRADVFVQTLEGRVLDPNEELNKLDSLLEEHKLETVDYVVDEKRKTANLTEQGNGKAEAYFHVENISDPTHMELMHYINQALKARTTMRRDIDYVVDNDEVKIVDEFTGRIMEGRRYSEGLHQAIEAKEGVTIKSESKTLATVTFQNFFRMYEKLAGMTGTGLTEADEFSEIYHMDVIEIPTNRPIDRTDREDAVYAHEEAKFRAIVREIQEIHATGQPILVGTVDIETSEKISKMLKKVGIKHHVLNAKQHRYEAEIVAQAGRFGEVTIATNMAGRGTDIVLGGNAEWMAKKQMEKDGDSAELIEWADSFRHVEPEETFPANSAGEESEEEAWITGREILDAREKFQRLKKEFSVETKENAEKVKAVGGLFILGTERHEARRIDNQLRGRSGRQGDPGASQFYISLEDKLMRLFGSERMQKFVESGAFPEDEPIQAGILTKSIERAQKKVESNNFATRKQVLDYDNIMNMQRNTVYGERNRVLNGEDMRDEIVEMIHGVVSDAVDSFCGEGIPPEQWEMEGLFNYLNNIFLPKGAVAIGQLQGMKPQDLKDQLTHIADDLYARKEEEITPSVMREVERMVLLRAVDTKWMDHIDAMDQLRKGIGIRAMGNEDPVRAFANEGYDMFNAMNESIREETVRVLYHIEPPKREVVRTAVATPTRAIGAGDEAEPENRPFVRKNKKIGRNDPCPCGSGKKYKNCHGRFDR
>NZ_LT632322.1|WP_147659357.1|343708_343954_-|hypothetical-protein
MAMVAVGAKRAFATICCGFGDGGSLAKMGFHHHHLRLRRWWWFAEIALPPPSSKEVMKLAPKIKSRPTAGGLKTPPKAASF
>NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31
MKQGIHPEYYENATVTCACGNTFTTGSTKKELRVDVCSACHPFYTGKQKTAERGGRVERFKKKYNID
>NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MKTIAQWAALLPQQEGYLALSYVLDTTPGALRAKSGESLDTAVTERYQEIVRRRLAGEPLQYAIGEWEFYGHLFQVDARALIPRPETERLVEMALQEDLAGKLVADIGTGTGAIALSIALEAHPKPRKLYATDCSADALVLAKENAARLLSSRGGIHAQPASAQPVPNDASASSQNMIEWVLGDGPSALPEAVDVLVSNPPYIDPQEKESLQDELQYEPASALFAGEPGKGGLALYQEWIPLLPARLQSHGVVLMEIGDRQGEAVSSLFRQAGFSAVTVHPDYTGRDRIVRATR
>NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1
MFESLEHIQSQLHEMEQQLADPALLADMNAWRKVNRAYVERKPIAKAYQEYKKAIDTAEEDREMLKEVQDADMEAMLKADLAEQEDIAQKKEEELKLLLVPKDPNDYKNVIVEIRAGAGGDEAGLFAGDLYRMYHMYAEKEGYTTEELDRTEQGIGGIKEATFMVKGEGAYSKLKYESGVHRVQRVPETESSGRIHTSTATVAVLPEAEDVDVELNLNDVRVDVYRSSGHGGQCVNTTDSAVRVTHIPTGIVVAIQDEKSQLKNKEKALHLLKTKLYDLELEKQNQEIASARHSQVGSGDRSERIRTYNFPQGRITDHRINRTIYQIHEFLDGDIGEMIEALQTEDQMKKLALVTDDSEQA
>NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase
MDKEQFLKQWNESTKRLFCKTIETATSFEKYAALSQTIMDHITDAWMETREKTKTMRNEYYFSAEFLVGRALGNNLLNLGILDEVKAVLKDIGIDFEQLEDEEDDAALGNGGLGRLAACFIDSAASEGYPVQGYGVRYSQGIFEQKFIDGFQREEGDDWTKKGDFWSQRREEEAKLVRFRDETVLAVPYDMPIIGYKNGIVNTLRLWQAEPLESGFDFDRFNNFQYDDALRELNRAEDITRVLYPNDMQRAGKVLRFKQQYFFTSASIQDLLTRYKENFPEDTNFRSFSALHSIQLNDTHPVIAIPELMRLLIDEEELSWDDAYDVATHTFAFTNHTVLQEALEKWSLDIVDEVCPRCLELIKEINQKMISVFRQQGMPEEQINTYRIIHDNVVEMAYLAVWCAVAVNGVAKIHTQILQTETFKQWVAVMPEKFSNKTNGVTPRRWLQYANPELSAFITKKLGSDAWHHDLTLLKGLERYADDPETLTELNAIKAIKKNQLVDYIERTEGITLDPDSIFDIQIKRLHEYKRQLLNILHILHLYNMLKKNPGLDMVPRTFIFGAKAAPGYFRAKAIIKFINEVARMVNADPDTRKKLRVVFVQNYRVSSAEKLFPAADISEQISTAGKEASGTGNMKFMLNATPTLGTYDGANIEIIADAGEENNFRFGATVEELEGIASSYNPLEYYHTKPEIKEVVDYLLDQRLSDHGTYMFLDVYNSLVAPQHGERGDEHYLLYDFESYAEAQKRVDTAYRDRLGWAKKCLMNLANCGEFSSDRTVREYVRDIWKVDTIQ
>NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase
MLVSAKEMLIKAAKEHYAVAQININNLEWTKAVLETAEELKSPVILGVSEGAGKYMGGHTTVAAMVRAMDEALGITVPVALHLDHGTYEGAKKCIEAGYTSVMFDGSHFPLEENLEKTTEIVRLAHEHGISVEAEVGTIGGEEDGVVGMGEIADPAECKRLADLGIDFLAAGIGNIHGVYPANWKGLDFDALQHIKEATGDMPLVLHGGTGIPKDMILKAISLGVAKINVNTECQLSFAKATREYIEAGKDQQGKGFDPRKLLAPGTAAIKETVKEKLEMFGSVGKAE
>NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein
MLWAKHRHRNRAKSRANRAKSRANRAKSRANRAKSRANRAKSRANRASRQRNRK
>NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein
MKQKRLLLALALSGAVLTACSSNPGFELVDAPRQESSGVEETKEVTELMEQEFAIVTEVDDTVKPGEYRIVQPGERGQSNITYEVSMSGGKEVSRKALSETVVKKPVEAIVKIAPTAKHGEIGAREIIGYSNPTSPHFVKPTTIGATMTDNSLVLRILADGKVEKDNFMVAQSSEKPRTEPSTTEKSRVPDIRIVPAPSRGGKTHTPTPTPPPAKPKPPVIPVLPNASSAPASSEQSSSSSSSQEQSSQQSSSSSSAQTSSDTQAPSSSQSQSKPESSKSSTTEAPPNPNPSGENTSPEEKPAP
>NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MTKKKHPVVDVRIEELAYPDRASGVVLSTIAHDPVGEMLELPVDHSKREAVAPMRMKGGLPGQVWRCRVKRSHAGVREVMPLQLLAPSPMEHRPTCPQAGICGGCNYQTISVESELLLKSRQLRELYAPLGLSSAISLYRSPLLEGYRSKMEYTFGDSTPGGPLTLGLHRPGHFYDILPTPLCNIVPEDFNSLRKAVERFCREREWTFYHRAKKSGYLRHLVLRAALTTGELMVNLVTTSERTWTALDTTEFLRLLHSLSLSMRLVSVFHTTNDSVADVVQADALDLLEGRSYLEERLFDLSFHVGPFSFFQPNVMGAKNLYSKALDLAGDLRGKTVYDLYSGTGTLAQIAASRAQRVIGVEIVEEAVEKAREACQRNGLANVRFVASDVLAELTRLADIGDRPDVVLLDPPRQGIHPKAVAHLIAAAPERIVYISCNPTTQVHDLSLFTAGGYRVEQVVAFDQFPRTKHVETVCLMSRKD
>NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein
MSITRSERLKMNKNITMIPARKKQGNTKTETPSPTLRVAAYCRVSTDSDEQATSYEAQVAHYTEYIQAQKGWELAGIFADDGISGTNTKKREEFNRMIDACEAGEIDIIITKSISRFARNTLDCLKYIRKLKEINIPVFFEKENINTMDAKGEVLITIMASLAQQESQSLSQNVKLGIQYRYQQGKVQVNAKWFLGYDKDADGHLVINSEQAKTVKRIYREYLEGLSMNKIAAGLEADGIRNGAGHTKWTPSNIRQILTNEKYIGDALLQKTYTVDFLTKKRVRNEGHMPQYYVENDHEAIIPKEIFLLAQDELVRRRNLSKRADGKRKAYSSNHCLSGLVICGECGEYYRRIHWNNRGCKSIVWRCMSRLTPGNNSCHARTVEEEFLKGIVLSAINRCIKDKGCFFAELEDRITHVIDHESSVDMKSIEQRLEDLQQMLMDRISNREPYEDVANEIDAVKEEKMQAELAQAKTDNQILRIQAMRDFLQAQTGILTTLDDALVRRMVDTITIHDKKIDVRFTSGVSVSIKQ
>NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein
MKDGKIAIHEEEACALKSLFENYLSGMSLKASAQSVGITFTHSVIRRLLENPIYAGSEGYPALISEEWLKQAHELRLSRAKNLGKEKLRHKRRPTFYVKTRFYMDEIDCGDRSALEQAVYVYNQIREVEDE

Crispr_ID: NZ_LT632322_3

• CRISPR_ID: NZ_LT632322_3
• CRISPR_location: 368491-368577
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT632322_3

Consensus_repeat	Method
CGAATATGGGCTCCTGGGCTTTGG	CRISPRCasFinder

spacers of NZ_LT632322_3

>3.1|368515|39|NZ_LT632322|CRISPRCasFinder
TGATTTTTTGCGATAAAAGGAGCCTTTTATTGCAATTTA

CRISPR arrays and Neighbor proteins around NZ_LT632322_3

CRISPR arrays

The CRISPR arrays of NZ_LT632322_3

>merge|NZ_LT632322|3|368491-368577|CRISPRCasFinder
CGAATATGGGCTCCTGGGCTTTGGTGATTTTTTGCGATAAAAGGAGCCTTTTATTGCAATTTACGAATATGGGCTCCTGGGCTTCGG

>NZ_LT632322|3|2|368491-368577|CRISPRCasFinder
CGAATATGGGCTCCTGGGCTTTGG	TGATTTTTTGCGATAAAAGGAGCCTTTTATTGCAATTTA
CGAATATGGGCTCCTGGGCTTCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein	unknown	unknown	gnl|CDD|377856
NZ_LT632322.1|WP_071705048.1|374688_375627_-|1,4-beta-N-acetylmuramidase	unknown	unknown	gnl|CDD|119376
NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31	unknown	unknown	gnl|CDD|376487
NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein	unknown	unknown	gnl|CDD|377851
NZ_LT632322.1|WP_071705049.1|375619_376039_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|377457
NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein	unknown	unknown	gnl|CDD|380155
NZ_LT632322.1|WP_083428144.1|372679_374251_-|recombinase-family-protein	unknown	unknown	gnl|CDD|238206
NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	unknown	unknown	gnl|CDD|236467
NZ_LT632322.1|WP_071705035.1|353417_353957_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein	unknown	unknown	gnl|CDD|238206
NZ_LT632322.1|WP_071705052.1|378657_380355_-|phage-tail-protein	unknown	unknown	gnl|CDD|377677
NZ_LT632322.1|WP_071705050.1|376035_376431_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705047.1|374299_374494_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|273938
NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl|CDD|340853
NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl|CDD|225174
NZ_LT632322.1|WP_071705051.1|376441_378643_-|tail-fiber-protein	unknown	unknown	gnl|CDD|310464
NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase	unknown	unknown	gnl|CDD|130918
NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239241

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein	gnl|CDD|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	1.34831e-05
NZ_LT632322.1|WP_071705048.1|374688_375627_-|1,4-beta-N-acetylmuramidase	gnl|CDD|119376	cd06414, GH25_LytC-like, The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.	1.85099e-80
NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31	gnl|CDD|376487	pfam01197, Ribosomal_L31, Ribosomal protein L31.	2.41268e-37
NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein	gnl|CDD|377851	pfam07501, G5, G5 domain. This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function.	8.72897e-14
NZ_LT632322.1|WP_071705049.1|375619_376039_-|phage-holin-family-protein	gnl|CDD|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	9.59825e-43
NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein	gnl|CDD|380155	NF012221, MARTX_Nterm, MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA. This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.	0.00297151
NZ_LT632322.1|WP_083428144.1|372679_374251_-|recombinase-family-protein	gnl|CDD|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	3.4909e-40
NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase	gnl|CDD|236467	PRK09328, PRK09328, N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional.	7.315e-90
NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein	gnl|CDD|238206	cd00338, Ser_Recombinase, Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase. Serine recombinases demonstrate functional versatility and include resolvases, invertases, integrases, and transposases. Resolvases and invertases (i.e. Tn3, gamma-delta, Tn5044 resolvases, Gin and Hin invertases) in this family contain a C-terminal DNA binding domain and comprise a major phylogenic group. Also included are phage- and bacterial-encoded recombinases such as phiC31 integrase, SpoIVCA excisionase, and Tn4451 TnpX transposase. These integrases and transposases have larger C-terminal domains compared to resolvases/invertases and are referred to as large serine recombinases. Also belonging to this family are proteins with N-terminal DNA binding domains similar to IS607- and IS1535-transposases from Helicobacter and Mycobacterium.	6.74256e-44
NZ_LT632322.1|WP_071705052.1|378657_380355_-|phage-tail-protein	gnl|CDD|377677	pfam06605, Prophage_tail, Prophage endopeptidase tail. This family is of prophage tail proteins that are probably acting as endopeptidases.	2.71334e-20
NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	5.17142e-82
NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase	gnl|CDD|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl|CDD|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	2.19914e-94
NZ_LT632322.1|WP_071705051.1|376441_378643_-|tail-fiber-protein	gnl|CDD|310464	pfam05895, DUF859, Siphovirus protein of unknown function (DUF859). This family consists of several uncharacterized proteins from the Siphoviruses as well as one bacterial sequence. Some of the members of this family are described as putative minor structural proteins.	1.56599e-63
NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase	gnl|CDD|130918	TIGR01859, Fructose-bisphosphate_aldolase, fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist. This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis].	5.57911e-139
NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase	gnl|CDD|239241	cd02931, ER_like_FMN, Enoate reductase (ER)-like FMN-binding domain. Enoate reductase catalyzes the NADH-dependent reduction of carbon-carbon double bonds of several molecules, including nonactivated 2-enoates, alpha,beta-unsaturated aldehydes, cyclic ketones, and methylketones. ERs are similar to 2,4-dienoyl-CoA reductase from E. coli and to the old yellow enzyme from Saccharomyces cerevisiae.	2.46718e-123

Protein sequences

>NZ_LT632322.1|WP_071705043.1|366656_367571_-|G5-domain-containing-protein
MKQKRLLLALALSGAVLTACSSNPGFELVDAPRQESSGVEETKEVTELMEQEFAIVTEVDDTVKPGEYRIVQPGERGQSNITYEVSMSGGKEVSRKALSETVVKKPVEAIVKIAPTAKHGEIGAREIIGYSNPTSPHFVKPTTIGATMTDNSLVLRILADGKVEKDNFMVAQSSEKPRTEPSTTEKSRVPDIRIVPAPSRGGKTHTPTPTPPPAKPKPPVIPVLPNASSAPASSEQSSSSSSSQEQSSQQSSSSSSAQTSSDTQAPSSSQSQSKPESSKSSTTEAPPNPNPSGENTSPEEKPAP
>NZ_LT632322.1|WP_157885047.1|366164_366329_+|hypothetical-protein
MLWAKHRHRNRAKSRANRAKSRANRAKSRANRAKSRANRAKSRANRASRQRNRK
>NZ_LT632322.1|WP_071705041.1|364169_365036_+|class-II-fructose-1,6-bisphosphate-aldolase
MLVSAKEMLIKAAKEHYAVAQININNLEWTKAVLETAEELKSPVILGVSEGAGKYMGGHTTVAAMVRAMDEALGITVPVALHLDHGTYEGAKKCIEAGYTSVMFDGSHFPLEENLEKTTEIVRLAHEHGISVEAEVGTIGGEEDGVVGMGEIADPAECKRLADLGIDFLAAGIGNIHGVYPANWKGLDFDALQHIKEATGDMPLVLHGGTGIPKDMILKAISLGVAKINVNTECQLSFAKATREYIEAGKDQQGKGFDPRKLLAPGTAAIKETVKEKLEMFGSVGKAE
>NZ_LT632322.1|WP_071705040.1|361684_364063_+|glycogen/starch/alpha-glucan-phosphorylase
MDKEQFLKQWNESTKRLFCKTIETATSFEKYAALSQTIMDHITDAWMETREKTKTMRNEYYFSAEFLVGRALGNNLLNLGILDEVKAVLKDIGIDFEQLEDEEDDAALGNGGLGRLAACFIDSAASEGYPVQGYGVRYSQGIFEQKFIDGFQREEGDDWTKKGDFWSQRREEEAKLVRFRDETVLAVPYDMPIIGYKNGIVNTLRLWQAEPLESGFDFDRFNNFQYDDALRELNRAEDITRVLYPNDMQRAGKVLRFKQQYFFTSASIQDLLTRYKENFPEDTNFRSFSALHSIQLNDTHPVIAIPELMRLLIDEEELSWDDAYDVATHTFAFTNHTVLQEALEKWSLDIVDEVCPRCLELIKEINQKMISVFRQQGMPEEQINTYRIIHDNVVEMAYLAVWCAVAVNGVAKIHTQILQTETFKQWVAVMPEKFSNKTNGVTPRRWLQYANPELSAFITKKLGSDAWHHDLTLLKGLERYADDPETLTELNAIKAIKKNQLVDYIERTEGITLDPDSIFDIQIKRLHEYKRQLLNILHILHLYNMLKKNPGLDMVPRTFIFGAKAAPGYFRAKAIIKFINEVARMVNADPDTRKKLRVVFVQNYRVSSAEKLFPAADISEQISTAGKEASGTGNMKFMLNATPTLGTYDGANIEIIADAGEENNFRFGATVEELEGIASSYNPLEYYHTKPEIKEVVDYLLDQRLSDHGTYMFLDVYNSLVAPQHGERGDEHYLLYDFESYAEAQKRVDTAYRDRLGWAKKCLMNLANCGEFSSDRTVREYVRDIWKVDTIQ
>NZ_LT632322.1|WP_071705039.1|360587_361673_+|peptide-chain-release-factor-1
MFESLEHIQSQLHEMEQQLADPALLADMNAWRKVNRAYVERKPIAKAYQEYKKAIDTAEEDREMLKEVQDADMEAMLKADLAEQEDIAQKKEEELKLLLVPKDPNDYKNVIVEIRAGAGGDEAGLFAGDLYRMYHMYAEKEGYTTEELDRTEQGIGGIKEATFMVKGEGAYSKLKYESGVHRVQRVPETESSGRIHTSTATVAVLPEAEDVDVELNLNDVRVDVYRSSGHGGQCVNTTDSAVRVTHIPTGIVVAIQDEKSQLKNKEKALHLLKTKLYDLELEKQNQEIASARHSQVGSGDRSERIRTYNFPQGRITDHRINRTIYQIHEFLDGDIGEMIEALQTEDQMKKLALVTDDSEQA
>NZ_LT632322.1|WP_071705038.1|359641_360526_+|peptide-chain-release-factor-N(5)-glutamine-methyltransferase
MKTIAQWAALLPQQEGYLALSYVLDTTPGALRAKSGESLDTAVTERYQEIVRRRLAGEPLQYAIGEWEFYGHLFQVDARALIPRPETERLVEMALQEDLAGKLVADIGTGTGAIALSIALEAHPKPRKLYATDCSADALVLAKENAARLLSSRGGIHAQPASAQPVPNDASASSQNMIEWVLGDGPSALPEAVDVLVSNPPYIDPQEKESLQDELQYEPASALFAGEPGKGGLALYQEWIPLLPARLQSHGVVLMEIGDRQGEAVSSLFRQAGFSAVTVHPDYTGRDRIVRATR
>NZ_LT632322.1|WP_071705037.1|358615_358819_+|50S-ribosomal-protein-L31
MKQGIHPEYYENATVTCACGNTFTTGSTKKELRVDVCSACHPFYTGKQKTAERGGRVERFKKKYNID
>NZ_LT632322.1|WP_071706049.1|355740_357900_+|FAD-dependent-oxidoreductase
MATTTKQPHPAQHTAENPALPEALAPLFTPWKIGTVEIKNRIVLTSMGGTNLLGWMEKNHFDETGAHFIRTIAENNVGLVLPGCQPVYNPMFGQWLYKNKRMYDDLAKWLPAFHQTGAKLFVQLTAGFGRSFTISPMMETLYTNPVLRFLSKPVMNLDKITASASEAPNRWSDKVPSRAMTVAEIQQMVEAFGKSAKLLKDAGVDGVEVHAVHEGYLLDQFTLKYVNHRTDAYGGSRENRYRFPVDIVREIKRVCGENFPVSLRYSVESKTKGFRQGALPGEEYTEVGRDMEESRWAARYLQDAGYDMLNCDNGTYDAWYWCHPPIYMPENCNLDEVKEIKKAVTIPVVPAGRMDPYVGAKEVAAGTIDGVGFARAFLADPEWVTKILEGRSEEIRPCICCHNACFNMSKWKGTPNMQELQDSLHLARCAVNAETMQWDKHYIKKTDAPKTVHIIGGGVGGMEAARVLKLRGHNPVIYEQTDRLGGVVIPGAAESYKKPMRDLLAWYRQEMERLDIPVHMNQSIAPDHDFGTDPVIVATGGKPISLSRVPGFDRTIEATDFLRALEGRREEEGVAVKKGVGRRVAVIGGSLTGCEIAYELALQGKEPFILEMKEDLIATEGVCLANSSYLREWFALHKVPVYLESTLVEVKEDAVTYKDASGALHEVPCDSVISAVGYRPDPLLDKAHTGAQTYFIGDCAGIGNIKTAVWQAYETAMKI
>NZ_LT632322.1|WP_071705036.1|354102_355368_+|trypsin-like-peptidase-domain-containing-protein
MDEQERLEQTEEWNEDARKAQSPHYEEAATRRIVREEIARNYRPKGSAARAVALVLCGALLGAGGGAALVASGNIPLPQQQEQAASATTNGNINISLKEGQTTVENAIAAKTIPSIVGITTIAKSVSNNPFLYGTPQYSESVGSGVIVSADGYILTNAHVVNGGNAKTVRVRLSNGEEAEAKVLWADPTLDLAVIKVEKKNLPAITFGDASKVQVGDKAVAIGNPLGLDLQSTLTSGYISGLNRSITLQDGNIMDGLIQTDAAINGGNSGGALLNAKGELIGINTAKPASADGIGFAIPVSTVKPIVDKIVADGTYTPLYMGINGANTKLVAASGVEGLPTDSGVVVRDVVAGSPAATMGIEPYDIIVAINNEPVESMNTLKTLLLKYKKGDTVDVTYYHGRDKKTGKMTFTDFSPEAIQR
>NZ_LT632322.1|WP_071705035.1|353417_353957_+|hypothetical-protein
MQRTTKQPRRRWMQIAASIPNREKEEERRQDLERFHAKVGDEKEWIVMRLDDVDALIEQLTRETETIRESLDRPHHERVSSLAPLTEAGKQHLSRKRLLRSSAELDVLLLEVHRHPVFRDIVADMQNLTVPETTLPVENESSVVASRKMLSIRDQLSDLLDNLYRLRRRLRRELLRLAR
>NZ_LT632322.1|WP_157885022.1|368977_370423_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MTKKKHPVVDVRIEELAYPDRASGVVLSTIAHDPVGEMLELPVDHSKREAVAPMRMKGGLPGQVWRCRVKRSHAGVREVMPLQLLAPSPMEHRPTCPQAGICGGCNYQTISVESELLLKSRQLRELYAPLGLSSAISLYRSPLLEGYRSKMEYTFGDSTPGGPLTLGLHRPGHFYDILPTPLCNIVPEDFNSLRKAVERFCREREWTFYHRAKKSGYLRHLVLRAALTTGELMVNLVTTSERTWTALDTTEFLRLLHSLSLSMRLVSVFHTTNDSVADVVQADALDLLEGRSYLEERLFDLSFHVGPFSFFQPNVMGAKNLYSKALDLAGDLRGKTVYDLYSGTGTLAQIAASRAQRVIGVEIVEEAVEKAREACQRNGLANVRFVASDVLAELTRLADIGDRPDVVLLDPPRQGIHPKAVAHLIAAAPERIVYISCNPTTQVHDLSLFTAGGYRVEQVVAFDQFPRTKHVETVCLMSRKD
>NZ_LT632322.1|WP_172619971.1|370695_372291_-|recombinase-family-protein
MSITRSERLKMNKNITMIPARKKQGNTKTETPSPTLRVAAYCRVSTDSDEQATSYEAQVAHYTEYIQAQKGWELAGIFADDGISGTNTKKREEFNRMIDACEAGEIDIIITKSISRFARNTLDCLKYIRKLKEINIPVFFEKENINTMDAKGEVLITIMASLAQQESQSLSQNVKLGIQYRYQQGKVQVNAKWFLGYDKDADGHLVINSEQAKTVKRIYREYLEGLSMNKIAAGLEADGIRNGAGHTKWTPSNIRQILTNEKYIGDALLQKTYTVDFLTKKRVRNEGHMPQYYVENDHEAIIPKEIFLLAQDELVRRRNLSKRADGKRKAYSSNHCLSGLVICGECGEYYRRIHWNNRGCKSIVWRCMSRLTPGNNSCHARTVEEEFLKGIVLSAINRCIKDKGCFFAELEDRITHVIDHESSVDMKSIEQRLEDLQQMLMDRISNREPYEDVANEIDAVKEEKMQAELAQAKTDNQILRIQAMRDFLQAQTGILTTLDDALVRRMVDTITIHDKKIDVRFTSGVSVSIKQ
>NZ_LT632322.1|WP_083428143.1|372253_372649_-|hypothetical-protein
MKDGKIAIHEEEACALKSLFENYLSGMSLKASAQSVGITFTHSVIRRLLENPIYAGSEGYPALISEEWLKQAHELRLSRAKNLGKEKLRHKRRPTFYVKTRFYMDEIDCGDRSALEQAVYVYNQIREVEDE
>NZ_LT632322.1|WP_083428144.1|372679_374251_-|recombinase-family-protein
MKALKKVTRIDGVATQRKQQKQMRIAVYCRVSTESDAQLESLEAQRKHYASYICTRDGWTLHDIYYERGVSAAKSKARPELRRMLRDCRLGKIDLVLTKSISRFSRNTADCLRMVRKLLELKIPVYFEKENINTSEMESELFLSILSSMAQDESASQSANVRWSIEQRFQSGTFIITCPPFGYRNDDGVMAIVENQAVIVREIFQLALAGYGGYSIARILNDQNIPSAHGGLWSSGSILAILKNEKYTGDCLFQKTYTDDAFKRHKNNGEKNAYLVRDHHKAIIDRKTYDAVNELIELKRENKGIIQESPKYLNRTVLSGKVRCKACGSVMKRITRYTQSGSYKMYACSTHLHSKKNCPFKAVYEDGILCAFASMMNKLTFAREAILEPLLSEMQGQKPKTYVKELKVANEAIREDSDKLDVLTRLSASGYLDRPHFLKEKNKLVTRIEERKKEREQLKIQEAGKDDTVINLEALCHYVKGRKVSERFCEEEFKRFVDAVEVVSRTEVCFILKCGLRLPERLA
>NZ_LT632322.1|WP_071705047.1|374299_374494_-|hypothetical-protein
MTNDINNKQPLPVQEDLMRDVYYRLAEAYVDELYAQGILAECEAQILHRQNRSVYRPFLYQLME
>NZ_LT632322.1|WP_071705048.1|374688_375627_-|1,4-beta-N-acetylmuramidase
MSKGIDVSKWNGSIDFNKVKADGIDFVIIRAGYGWDTSQKDRTFEQNYARAKAAGLHVGAYWYSYARSADNARSEAKVCKQIIAGKQFDYPIFFDLEESSQLSRGQAFCDSLIQAFCNEMEAGGYFAGFYTSASVARNILSKSIRKRYAFWCAQWANTNSFEGESGLWQYSSKGSVSGIAGNVDLDISYIDYPSLIRGGGFNGYAKGSTAPTAKPAPAPEKKTVETLADEVIKGLWGNGEERKRRLTASGYSYDAVQKKVNERLSVKPKKSINTLAREVIHGDWGNGNERKNRLTKAGYNYDAVQKRVNELL
>NZ_LT632322.1|WP_071705049.1|375619_376039_-|phage-holin-family-protein
MKEFWNSIQLIFTGIGGWLGFYLGGFDGLLYALIAFVITDYITGIMCAVADKKLSSAVGFKGIARKVLIFLLVGIGHMIDAQVIGTGSVLRTAVIFFYLSNEGLSLVENATHLGLPVPKKLKVVLAQLHERAEKEETHE
>NZ_LT632322.1|WP_071705050.1|376035_376431_-|hypothetical-protein
MQILTDEQGFITSFALDGMLVGGAECAEPEDIEDFALHYQCYRIRDGDLVLDKKRLVAKSKNAAKDAIRERRCKECFPVINRGTPWYDRLTEQQKKELNAWYLAWLDATETGAIPEMPEWLSTYYVLGGTR
>NZ_LT632322.1|WP_071705051.1|376441_378643_-|tail-fiber-protein
MASSGSFSGSIHGGHYVLRVDWKQTKDITNNHSTITATMVLVNDWTLYISGRTNNTCTIDGQSQAFSSPAVDTTGSHTLGSVTKTVNHNSDGSKTLNISAVFHIEATISGTYYSTITANASITLDSIPRASSVSASSISMGTATTIKISRAVSSFTHTLAYRFGSVSSAIAIKTTGTSLSWTPPLSLASQIPNSTSGTCTITCYTYNGGTYIGSKATTITLYVPSTIKPTIGSLTASHIDGTVPSTWGVYVQYKSKATLAISGATGSYGSTIRSYSITGGGFSGSSSSLTTGFLNDYGTTTFTAKVTDSRGRTSDAKTVSISVLPYYSPRFLSAQSERADSTGTPKGDGTYVRALLEFYFASVGGKNTITTSVSYKKESDATWTDAATTFTSNTPFTFGSGSISPENTYEVKYTLTDAFTSISITDSISTAAVVMDFKNGGNGLAIGKVSEIEKCFEVAPDWSVKVYGLLLPAYIASLSGGLPFGVCNDAADVVEKTGECPDFQTLNTGAVVLMKFMHNNTATFPRINVNGTGLKYIVNVGRTAVGTNYWRPEQTVILIYDGIFWVALTTPLADTSYFGITKLSTSTSSTSTSTAATSSAVKAAYDRNSWPSISLTSPLAVSSGGTGASYASAARSNLGITATSLYSGAITTGSTTFSKSYNFFVIIGQPSTASSRCALVVPSAQLTTTATNYQIADESNYYAFKLYYSGTTVTLAYYDRSSNGQIIRVFGVN
>NZ_LT632322.1|WP_071705052.1|378657_380355_-|phage-tail-protein
MSQFTVYVDGALFYHPDLSELAVTEAKIEEDAQSIDRFILSAPFTHPYITKIHPLASTIICKKGDQIVFEGRVLDDGTDFYNTHTWICESALAFLKDSLQPPYHYQGPLRGLLELFLSSHNSAVEEKKQFVLGTVTVSDTNDYVAYENGDYSVTLDAIKEKLLDTHGGYLKVSYTADGKKQLDYLADFTAASLQTVEYGKNLLDVKINRDHTKRVSMLIPLGAKSTETDSEGNETERRVDITSVNGGLNYVEDADTTAEIGKIWTTEIWDDVTLPENLLRKAQARLPELKDGITSMELSIVDESDTGSTLSEMHAGEYIRCLSKPHGIDGRYLCLARTRDYLHPASNTITIGARNITLSKAATEQSKNLEALSVDIEGKTEEINSAVSKADTALAEATQAKDAASSLEVNVQQFYSEITKTAEQINSAVREEYVSKSDLETLRQDFSSSITQTSTELRLDFHAKTDEIRGNVIANQQLLEEYIRFRGALIELGKIGNAFTAELSNEQLAFKENGQVIAYISNQSLVITNAEIRYRLSLGTEGRGWFDFIPRPTGNLSVVWRASSN

Crispr_ID: NZ_LT632322_4

• CRISPR_ID: NZ_LT632322_4
• CRISPR_location: 646546-646660
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_LT632322_4

Consensus_repeat	Method
CCCTGTTTTAACGCGATATTTCCCCTTCG	CRISPRCasFinder

spacers of NZ_LT632322_4

>4.1|646575|57|NZ_LT632322|CRISPRCasFinder
CCAGGGGTGCGAGCCCTGACAACTTCTCGTTTCAGCAATTTGTCAGGGTACATCGGA

CRISPR arrays and Neighbor proteins around NZ_LT632322_4

CRISPR arrays

The CRISPR arrays of NZ_LT632322_4

>merge|NZ_LT632322|4|646546-646660|CRISPRCasFinder
CCCTGTTTTAACGCGATATTTCCCCTTCGCCAGGGGTGCGAGCCCTGACAACTTCTCGTTTCAGCAATTTGTCAGGGTACATCGGACCCTGTTTTAACGCGATATTTCCCTTTCG

>NZ_LT632322|4|3|646546-646660|CRISPRCasFinder
CCCTGTTTTAACGCGATATTTCCCCTTCG	CCAGGGGTGCGAGCCCTGACAACTTCTCGTTTCAGCAATTTGTCAGGGTACATCGGA
CCCTGTTTTAACGCGATATTTCCCTTTCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase	unknown	unknown	gnl|CDD|133428
NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_LT632322.1|WP_071706073.1|641621_642317_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319847
NZ_LT632322.1|WP_071705204.1|634685_636602_-|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|173847
NZ_LT632322.1|WP_071705205.1|637091_638309_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NZ_LT632322.1|WP_162272150.1|638539_639901_+|DUF1727-domain-containing-protein	unknown	unknown	gnl|CDD|377986
NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter	unknown	unknown	gnl|CDD|340891
NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|223740
NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_LT632322.1|WP_071705214.1|649201_649348_-|thioredoxin	unknown	unknown	unknown
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_LT632322.1|WP_071705207.1|639897_640596_+|hypothetical-protein	unknown	unknown	gnl|CDD|225974
NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter	unknown	unknown	gnl|CDD|225127
NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|223425
NZ_LT632322.1|WP_071705209.1|644882_645311_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071706072.1|641040_641532_+|thioesterase	unknown	unknown	gnl|CDD|223894

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	6.4e-20	66.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase	gnl|CDD|133428	cd05292, LDH_2, A subgroup of L-lactate dehydrogenases. L-lactate dehydrogenases (LDH) are tetrameric enzymes catalyzing the last step of glycolysis in which pyruvate is converted to L-lactate. This subgroup is composed predominantly of bacterial LDHs and a few fungal LDHs. Bacterial LDHs may be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. LDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	8.70047e-175
NZ_LT632322.1|WP_071706072.1|641040_641532_+|thioesterase	gnl|CDD|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	9.81299e-07
NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	0.00105836
NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.14938e-77
NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase	gnl|CDD|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LT632322.1|WP_071705204.1|634685_636602_-|acyl-CoA-dehydrogenase-family-protein	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	7.34495e-06
NZ_LT632322.1|WP_162272150.1|638539_639901_+|DUF1727-domain-containing-protein	gnl|CDD|377986	pfam08353, DUF1727, Domain of unknown function (DUF1727). This domain of unknown function is found at the C-terminus of bacterial proteins which include UDP-N-acetylmuramyl tripeptide synthase and the related Mur ligase.	9.52269e-11
NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter	gnl|CDD|340891	cd17333, MFS_FucP_MFSD4_like, Bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4, and similar proteins. This family is composed of bacterial L-fucose permease (FucP), eukaryotic Major facilitator superfamily domain-containing protein 4 (MFSD4) proteins, and similar proteins. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. The MFSD4 subfamily consists of two vertebrate members: MFSD4A and MFSD4B. The function of MFSD4A is unknown. MFSD4B is more commonly know as Sodium-dependent glucose transporter 1 (NaGLT1), a primary fructose transporter in rat renal brush-border membranes that also facilitates sodium-independent urea uptake. The FucP/MFSD4 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18001e-29
NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	7.32546e-06
NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.70332e-25
NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.01938e-43
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.42049e-19
NZ_LT632322.1|WP_071705207.1|639897_640596_+|hypothetical-protein	gnl|CDD|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	0.00562649
NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter	gnl|CDD|225127	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism].	2.16226e-07
NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein	gnl|CDD|223425	COG0348, NapH, Polyferredoxin [Energy production and conversion].	8.08173e-20
NZ_LT632322.1|WP_071706073.1|641621_642317_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	2.06889e-92

Protein sequences

>NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein
MIDIDFIQFNMAEMGALVDCMTPTGRYVSFPNRFIFQEAVFNYNRDDPFVMQDVFVLIDGKEDRQKALEIAGKVAYEKYQNIIADYDEEEMQHFENAVGAMSGDAKPKIRATLDPNGVRIYIQFFTAYDEIGKNKMIMENALYDALLANGFTFPSPQYIRLLK
>NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel
MQQYFEYLRDIGDDQHSFLEKIAVSVLIFLAIFVVRLLVAKCLDGVVKDEKRRHRILSATRFFTVLLTIYLVLYVWFSRAKSVGLIVGIGLALLVLALKDLIMDIFAFIYIFLRRPFAVGDLVEIQGI
>NZ_LT632322.1|WP_071705209.1|644882_645311_+|hypothetical-protein
MTLFLNEEDMHKNLAELLPEGETYQVQIWGLLLGGSSLERFILGKMATLNNVCTYLGVTEKHLVMALMGTVSISQRQGELALPLDEIDQVQVKHSFLPGKSTVILQVGQEKIKLSLMSRNPVTASIKNQKEEIATFCSLLAK
>NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease
MRNPMNKRIPRMLLHQPAHYVPLFLLLLITIIFCSAFFLVQGSVERLYYDFMDRSHVEDGRFTTLSPLSDATWKRVEEKGVQLEKNYYIEAKDGDADLQLYAVRRKSNVPDVIAGRLPEKEDEVALDVNYVREHAYALGRDITISGRSMRLVGTVVLPDYIAMLHTRSDLVMDTKNFGVGIVSEDGLLRFPQQSLQYNYSYRENKTSATKKEANDTLKELTKTVYEDNILTEAMTQAQNKRISYMMDDMGGDVPMMRMVLILAVASIAFVFTMQTRNQILSEASAIGTLMASGYTRRELIVHYMLLPTVAVLSAAVLGNLITYTVGYKLYMNLYYDSFSLPVFHPLFNARAFLLTTVIPAVIVTLIQFLMLMTKLRLRPLRFLRHELGRKPRVSKMRLSRFAFFSRLRFLSRYRLKVLFNNKLNVLVLLFGVTLSSIFLCYGLGMRPIFERHADLMQKEFPAKVQTFVRPGTVLDAADEEAEKFGYAAFDLSINGDVHPFALYGVAPDSRYFDAQAIDPLRDKEIQASEGLMKRFGLVEGDNITVVNPYTGKTYTFCIRAMRRQAVTLSAYMPLAAFNAVMGYDKDAFSGYYSEHKLSLDPASVVSCIDLDTVGKASDHFLDTFGQIIGPIVIIAVLFYFIFIDFLSKAIVDKAKTEIAYLKIFGYTDAETTGIYLRATGILLGLFLLVLPFLLRFLLAILLTAALAKLDSYMDPHVPMQIYFLVSVTGAVLFFLVQALQKRKIAKISMTETLKEV
>NZ_LT632322.1|WP_071706073.1|641621_642317_+|ABC-transporter-ATP-binding-protein
MITIRNLHKFYGEGENRVEVLKNIDLTIADGEVVCVVGPSGSGKSTLLNILGGIEDIDEGEVTVSDVALHKAGKKELEQYRRHHVGFVFQFYNLISNLNVKENIEVGAYLSTNPLNVDETIDTLGLRDQTHKYPNQISGGQAQRTSIGRAIVKNPSLLLCDEPTGALDYESAKDVLRLIETLKEKYHPIIIIATHNTQIARMCDTTIRLHNGAVLEVAPNLQPITAEEVSW
>NZ_LT632322.1|WP_071706072.1|641040_641532_+|thioesterase
MVENNKAKSIAIQDTYGKRFQHCWGCGPKNEEGMHLKSYPSEDGEQCVCHVTPSKQFTGGVPANLFGGMIAMIFDCHGTASAAWFAHRKKGLTLTADTVIGRFITAHLEVDFKKPVPMEEEVTVTAMVEEIGERKVIVAMEMEAGGVVRAKARMVAVGVKDNM
>NZ_LT632322.1|WP_071705207.1|639897_640596_+|hypothetical-protein
MKIEVLYDEFYIFGEKANVEYLKRMFSEEAIHETSFGEVPYFTTSPVDAILLGPMQESNLARVTKELMPYRDKLKERIEEGVLFVSINNALDILGRSLEVVEEGEEPTLSLFSYTAVRDYTKRYSELFVADWAGQEVIGERMGFSQYYGNESCAIYTSKTGKGFNQDTNLGGYRYKNAFLIDALGVMLVTNPPLARRLFSYFGMDKPLPFEKEAEEAYKNKLNLLKTDFKLS
>NZ_LT632322.1|WP_162272150.1|638539_639901_+|DUF1727-domain-containing-protein
MNNTLTLLLGKAIKKAANLAGKEGSDFTGRLIARLEPDAKYKISKPEKNICVSGTNGKTTTVNILADSVRLMEGKVCSNFHGANLEHGVLGALLDSASLKNTQPKVGVFEVDELSTYRICDFLKPSTFTITNLFQDSFERNANTGYIKKRLSFGIPKDVKLILNASDAISAYIRPDNERVYFDVLPLSFETQCLDSKIQDLIYCPHCGEKVHWTFKRYHHLGHYHCDCGNFSNPEATYFVYDADREKRILYVQDHDQKVTLHALGSSIESMYNQIAAYATLRENGYSYEQISSAMAQIELTKERHQESHHADLHFYSIVTKGYNPIAVTRNLDAIRKNPNRKEIIWIIEDYWEKKTPMRTPGWLFAVDFDYLDETVSHFIILRSRNTYEIKLSCLLDGVPPEKIVVVDRVEDINSILDPSVKDIYLLHDFGPPWTTIAQKFEKTILKERMERS
>NZ_LT632322.1|WP_071705205.1|637091_638309_+|hypothetical-protein
MKKKNASWKGKTLLLLLTLLSLAVVISACGKKGGEANGPSTDSTMVASEENASSGNQKASTSEEAPQIVPLDPAVAEAIQKGLAEHAQILPGTVRIYSSGKEMADAMMRYSKEQGDIGLVKRIQFGVKRTSDPNEPFHSELEEPFVLLELDGERNVTASNAATEPRPVRVHYINLAPHAKEEDLATWKEWENKKVVFLAPSPQDLYWRDEGFFPFHAPNVYNKALRPYAISDFRALEAIKGLDAPIAHTWSFADFCGDYAYYSGAGAWGILFHLEKDGRFSLSYQDVDRDEILQSELTGQLSNFAVTDDGYTFTIASLQSSVAQGEEKVTEKDGRKLKTVYEDFGMKVGGTGTIYPSNTPRELFREEVVNLMDFARVSSEVLGITLKPTITLSPELTVWWAQENQ
>NZ_LT632322.1|WP_071705204.1|634685_636602_-|acyl-CoA-dehydrogenase-family-protein
MGYQLTQEHEALRKIVRDFAEKEIKPIAFRLDQGEEFPEEIVQHMGEMGLMGIPYEKEYGGQGLDATSYAITVEELSRVDGGVGVICSAHTSLGSWPIWAFGTEEQKQKYLVPLAKGEKIGAFGLTEEHAGSDASGTQTTAVLDGDHYVLNGGKIFITNGYRADTYVVFAVTSPEKGNHGISAFIVEKDFEGFTFPTQYDKLGIRSSITSELNFKNVIVPKENLLGKEGEGFKIAMATLDGGRIGIASQALGIAQGAFEATVNYTRERIQFGQPIAANQGVSFKIADMATRIEASRHLIYQAAELKTKHAKYTKEAAMAKMFASDTAMWVTTEAIQLHGGNGFIKGFDVERMFRDAKITQIYEGTNEIMRVVIAGQIIGRIGRKKKAAMVADTGKAGAVTGPRKNIMFEGTPEEQVKQLVEALKKDGYAFDTTVDVYAPVDEVERLVSVGQGIGDKENLAVAEELAKAVGGAISSSRPVAETLGYLPIERYVGMSGQKFKGNLYFAMGISGAGQHLRGIKEAATIVAVNTDAGAPIFANADYGIVGDIMEIMPLLTEALEQGQERHPAEGFEKKKRNVPQEPRTKSGIHVCNGCGHEYDPAKGDPDSGIAPGTPFDQLPDTYLCPKCGDPKSGYISIE
>NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase
MNTKKASLLLLATGLALSLAACGGKKPAESSQTTESGMSVPAAEAGKTSPSSEKGGSEVDAKLAELHDQENAIFSKDQELWDKLFLSANKNSGMISDGTNYGDFLLQTIESAKDKFTEAELKTLKAGAEEIRAIEEKILALEKEAPKDKKGGNSGAKQGAATPFPDFTGKDLDGNNVDSGIFRQHAVTVINFWFSTCNPCVGELGDLDALHKQLKDKDGIVVGVNSFTLDGNKDAIAEAKSILQKKNATYPNITFASDSEAGKFVKNIMAFPTTVVVDRDGNIVGDPILGSVAEGSGKKALEERIEQALKNDANKDAAYKENTKK
>NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein
MADPKKSKSRLLSRFRGWGQAGATLLTNIHLPNFFTGTLYQGNGKMVCVPGLNCYSCPAASGACPIGSFQAVVGSSKFRFSYYITGILILLGVLLGRFICGFLCPFGWFQELLHKIPTKKFSTKRLRPLTFLKYIILVVMVFLLPLLVVNEIGLGEPFFCKYLCPQGVLEGAIPLSLVNSGIRAALGALFTWKLGILLTVVVLSILFFRPFCKWICPLGAFYALFNRISLLQIQVEEHRCISCGKCAKACKMDVDVLKTPAHTECIRCGMCINACPTGALHFRYGLGCGKKRVPEAAESEKPVVAEK
>NZ_LT632322.1|WP_071705214.1|649201_649348_-|thioredoxin
MKTKKRSITQIALLVAAVGMIIVGAMRGEVQTVLAKAIRLCMECVGIG
>NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor
MRLLLVEDEPFLSDSIAKSLRRQGYSVDICADGEAAIEAVSLDPYDLVLLDLNLPKVDGMTVLRTIRAEDLQTPVLILSARSEIADKVHGLDAGANDYLSKPFHLEELAARVRSLLRRDFIQQEVCLRFGALTFDTRTRTTTVGEQVIALTKKESGILEYLLMHPGRPISQEELMEHVWDGSVDSFSNAIRVHISALRKKLRAALGYDPVRNRIGEGYLLEEPTP
>NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase
MIRRSLQWRIALMTSLLIAISCITMMILLSGSGLRRMEEIGKNIEAFELHLDSEDVAPGDSATETPGVSPDSLPGSASDSISRETPSESFPPQDMRREQNLTIIIDEAQAQFTLTSWYVTAGVTILSGIIAYFVSGHALRPLEDFSRQIEKVQLTNLENMHVSTDTLAEFRSIADSFNDMLDRLHVAFAAQRQFTGNAAHELRTPLALLQMRLDAFAEEHPDTDKELTQLITSLREQTERLSETVTILLEMSSARHVPRTDHVSILPMLEEIVADLTPLAEQKQVSLSFGGDDVSLLASDRLLSRLFFNLTENAIKYNRPGGSVSLSVASLDGNEGVSDSAVRSVAVSAPDNASRRTDGALESGVVVTLTDTGLGIPEEEWETIFQPFYRLDSSRSRQQGGVGLGLALAGEIVKLHNGTLRVVESSSAGTILRVTLPFSS
>NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator
MENKTMPKHPPAPPEPDRIKRQLQIVSDFQIVSDIFKQLGDTTRIRIFWLLCHHEECVQDISALLEMSSPAISHHLRPLRNSNLVVSRREGKEVYYRAADNAQSQLLHQMIEQVMEIACPK
>NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter
MKKTYAIEVDCANCANLMEEAANKTSGVEKANVNFMMQKMTVHFADGADANDVMDEVYKACKKIEPDCSIEY
>NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase
MPKKQRIMLKRILASAVLLFVLELLPAETFATLDASLFSGAGRGLRLALYVVDYGIIGYDILQKALQGMRNKRLFDENFLMAVATIGAMTLAIIEDGDYLEAIAVMLFYQIGEWFQRYAVGKSRRNISALMDIRPDYARIERDGEWIKVDPDEVPVGSHIMVHPGEKIPLDGVVMEGTSSLNTAALTGESLPRDVHEGEEVLSGCLSMTGVLTIRTTKEFEQSTVSKILDLVENASSRKAQSEEFISRFARVYTPAVCGAALALAVLPPLVRLFFLHLPAAWMVWIYRALTFLVISCPCALVISIPLSFFAGIGGASRAGILVKGSNYLEMLSKTGILVMDKTGTLTQGVFEVNALHHAICEEERLIELAALAESASSHPISKSLLRAYGKKIDTDRVTNIRELSGKGVLARVDGIEVAAGNDKLMEHLGVEYQNCHMTGTIIHMALDGEYAGHIVISDRLKPSAPKAIRALKSVGIHHMVMLTGDSDKVAQEIAQKLGIDEVVSELLPDGKVENVERLLQTKRKGEQLAFVGDGINDAPVLALADIGIAMGAMGSDAAIEAADVVLMDDDPMKIAQAMRISRHCLGIVKQNIVFALAVKFVCLSLGALGLAGMYLAIFADVGVMILAVLNAMRCLRVGGDDTVSALSVR
>NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase
MTHRVDNRKVAVVGCGFVGSSSAFALMQSGLFSEIALVDVNREKAEGEALDISHGVPFVGQVKVYAADYADIMDAAIVVVTAGAAQKPGETRLDLVNKNIRIFQSILPEFKKRNYGGILLVVSNPVDILTLAALELSGLPEQRVIGSGTVLDTARLKTALGEHLDVDSRSVHSFIIGEHGDSEMVAWSSTNVSGIPLNDFCEMRGHFSHDEAMERIADEVRNSAYEIIAKKHATYYGIAMSVVRICKAIVMNERSILPVSTMMHGEYGIDGICLSMPVIVGEEGAGVHVPLVLNDEEQEKLLASANALKEVARSAGL
>NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter
MLQLLLVLIYFAFISLGLLDALLGAAWPSLYPSLGVPISYAGVISMIISAGTIVSSLLSDRLHRRFGTGRITAFSVSLTAIALFGFSFSTSFIQLCVWAIPYGLGAGSVDAALNNYVALHYESRHMNWLHCMWGIGASLGPYLMGLCLTHGWGWASGYRSVGAIQVVLSAVLLFTLPLWKKAEGPRAAATSVGATSKEKSAPASGLSAILSLPGAKAILLCFFCYSALEATVGLWASSFLSLAIGVDPKVAAGFAGLFYLGITGGRAASGFLSLRFDDDALIRGGLLTIGLGLVFLGMSLFCGMLWANPAASLPPMLALIGLILMGLGCAPIYPGIIHSTPAHFGEERSQAMIGMQMACAYVGSCFLPPLFGMLARSVSVALLPLYVFLLLALMGFMHRRVVRATAVR

Crispr_ID: NZ_LT632322_5

• CRISPR_ID: NZ_LT632322_5
• CRISPR_location: 652089-652252
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: csa3

Consensus repeat of NZ_LT632322_5

Consensus_repeat	Method
TTTTGTGTCCGAGAAAACGCAAAATGCGAGAATAGGG	CRISPRCasFinder

spacers of NZ_LT632322_5

>5.1|652126|26|NZ_LT632322|CRISPRCasFinder
ACACAGTTTCGCTGTATAGCAGCTGC
>5.2|652189|27|NZ_LT632322|CRISPRCasFinder
GCACAGTATTTGCCGCAAGTAGGCTTT

CRISPR arrays and Neighbor proteins around NZ_LT632322_5

CRISPR arrays

The CRISPR arrays of NZ_LT632322_5

>merge|NZ_LT632322|5|652089-652252|CRISPRCasFinder
TTTTGTGTCCGAGAAAACGCAAAATGCGAGAATAGGGACACAGTTTCGCTGTATAGCAGCTGCCTTTTGTGTCCGAAAAACGCAAAATGCGAGAATAGGGGCACAGTATTTGCCGCAAGTAGGCTTTATTTGTGTCCGAGAAAACGCAAAATGCGAGAATAGGG

>NZ_LT632322|5|4|652089-652252|CRISPRCasFinder
TTTTGTGTCCGAGAAAACGCAAAATGCGAGAATAGGG	ACACAGTTTCGCTGTATAGCAGCTGC
CTTTTGTGTCCGAAAAACGCAAAATGCGAGAATAGGG	GCACAGTATTTGCCGCAAGTAGGCTTT
ATTTGTGTCCGAGAAAACGCAAAATGCGAGAATAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705225.1|662458_663079_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NZ_LT632322.1|WP_071705226.1|663083_663842_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl|CDD|224982
NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226957
NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319847
NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|223740
NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NZ_LT632322.1|WP_071705223.1|660077_662054_+|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|235505
NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter	unknown	unknown	gnl|CDD|340891
NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_LT632322.1|WP_071705214.1|649201_649348_-|thioredoxin	unknown	unknown	unknown
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NZ_LT632322.1|WP_071705222.1|657915_658782_+|radical-SAM-protein	unknown	unknown	gnl|CDD|214792
NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter	unknown	unknown	gnl|CDD|225127
NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|223425
NZ_LT632322.1|WP_071705209.1|644882_645311_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705224.1|662063_662399_+|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
NZ_LT632322.1|WP_071705227.1|663972_665250_+|alanine-racemase	unknown	unknown	gnl|CDD|143481
NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase	unknown	unknown	gnl|CDD|133428

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	6.4e-20	66.4	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705225.1|662458_663079_+|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	1.54504e-97
NZ_LT632322.1|WP_071705226.1|663083_663842_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl|CDD|224982	COG2071, COG2071, Predicted glutamine amidotransferases [General function prediction only].	6.23591e-74
NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	0.00105836
NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.14938e-77
NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase	gnl|CDD|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	7.32546e-06
NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	7.34495e-06
NZ_LT632322.1|WP_071705223.1|660077_662054_+|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	1.08221e-174
NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter	gnl|CDD|340891	cd17333, MFS_FucP_MFSD4_like, Bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4, and similar proteins. This family is composed of bacterial L-fucose permease (FucP), eukaryotic Major facilitator superfamily domain-containing protein 4 (MFSD4) proteins, and similar proteins. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. The MFSD4 subfamily consists of two vertebrate members: MFSD4A and MFSD4B. The function of MFSD4A is unknown. MFSD4B is more commonly know as Sodium-dependent glucose transporter 1 (NaGLT1), a primary fructose transporter in rat renal brush-border membranes that also facilitates sodium-independent urea uptake. The FucP/MFSD4 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18001e-29
NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.01938e-43
NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.70332e-25
NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.42049e-19
NZ_LT632322.1|WP_071705222.1|657915_658782_+|radical-SAM-protein	gnl|CDD|214792	smart00729, Elp3, Elongator protein 3, MiaB family, Radical SAM. This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases.	1.30489e-27
NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter	gnl|CDD|225127	COG2217, ZntA, Cation transport ATPase [Inorganic ion transport and metabolism].	2.16226e-07
NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein	gnl|CDD|223425	COG0348, NapH, Polyferredoxin [Energy production and conversion].	8.08173e-20
NZ_LT632322.1|WP_071705224.1|662063_662399_+|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	9.85091e-39
NZ_LT632322.1|WP_071705227.1|663972_665250_+|alanine-racemase	gnl|CDD|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.49616e-136
NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase	gnl|CDD|133428	cd05292, LDH_2, A subgroup of L-lactate dehydrogenases. L-lactate dehydrogenases (LDH) are tetrameric enzymes catalyzing the last step of glycolysis in which pyruvate is converted to L-lactate. This subgroup is composed predominantly of bacterial LDHs and a few fungal LDHs. Bacterial LDHs may be non-allosteric or may be activated by an allosteric effector such as fructose-1,6-bisphosphate. LDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	8.70047e-175

Protein sequences

>NZ_LT632322.1|WP_071705217.1|651453_651819_-|winged-helix-turn-helix-transcriptional-regulator
MENKTMPKHPPAPPEPDRIKRQLQIVSDFQIVSDIFKQLGDTTRIRIFWLLCHHEECVQDISALLEMSSPAISHHLRPLRNSNLVVSRREGKEVYYRAADNAQSQLLHQMIEQVMEIACPK
>NZ_LT632322.1|WP_071705216.1|650125_651448_+|HAMP-domain-containing-histidine-kinase
MIRRSLQWRIALMTSLLIAISCITMMILLSGSGLRRMEEIGKNIEAFELHLDSEDVAPGDSATETPGVSPDSLPGSASDSISRETPSESFPPQDMRREQNLTIIIDEAQAQFTLTSWYVTAGVTILSGIIAYFVSGHALRPLEDFSRQIEKVQLTNLENMHVSTDTLAEFRSIADSFNDMLDRLHVAFAAQRQFTGNAAHELRTPLALLQMRLDAFAEEHPDTDKELTQLITSLREQTERLSETVTILLEMSSARHVPRTDHVSILPMLEEIVADLTPLAEQKQVSLSFGGDDVSLLASDRLLSRLFFNLTENAIKYNRPGGSVSLSVASLDGNEGVSDSAVRSVAVSAPDNASRRTDGALESGVVVTLTDTGLGIPEEEWETIFQPFYRLDSSRSRQQGGVGLGLALAGEIVKLHNGTLRVVESSSAGTILRVTLPFSS
>NZ_LT632322.1|WP_071705215.1|649451_650129_+|response-regulator-transcription-factor
MRLLLVEDEPFLSDSIAKSLRRQGYSVDICADGEAAIEAVSLDPYDLVLLDLNLPKVDGMTVLRTIRAEDLQTPVLILSARSEIADKVHGLDAGANDYLSKPFHLEELAARVRSLLRRDFIQQEVCLRFGALTFDTRTRTTTVGEQVIALTKKESGILEYLLMHPGRPISQEELMEHVWDGSVDSFSNAIRVHISALRKKLRAALGYDPVRNRIGEGYLLEEPTP
>NZ_LT632322.1|WP_071705214.1|649201_649348_-|thioredoxin
MKTKKRSITQIALLVAAVGMIIVGAMRGEVQTVLAKAIRLCMECVGIG
>NZ_LT632322.1|WP_071705213.1|648285_649209_-|4Fe-4S-binding-protein
MADPKKSKSRLLSRFRGWGQAGATLLTNIHLPNFFTGTLYQGNGKMVCVPGLNCYSCPAASGACPIGSFQAVVGSSKFRFSYYITGILILLGVLLGRFICGFLCPFGWFQELLHKIPTKKFSTKRLRPLTFLKYIILVVMVFLLPLLVVNEIGLGEPFFCKYLCPQGVLEGAIPLSLVNSGIRAALGALFTWKLGILLTVVVLSILFFRPFCKWICPLGAFYALFNRISLLQIQVEEHRCISCGKCAKACKMDVDVLKTPAHTECIRCGMCINACPTGALHFRYGLGCGKKRVPEAAESEKPVVAEK
>NZ_LT632322.1|WP_071705212.1|647122_648100_-|TlpA-family-protein-disulfide-reductase
MNTKKASLLLLATGLALSLAACGGKKPAESSQTTESGMSVPAAEAGKTSPSSEKGGSEVDAKLAELHDQENAIFSKDQELWDKLFLSANKNSGMISDGTNYGDFLLQTIESAKDKFTEAELKTLKAGAEEIRAIEEKILALEKEAPKDKKGGNSGAKQGAATPFPDFTGKDLDGNNVDSGIFRQHAVTVINFWFSTCNPCVGELGDLDALHKQLKDKDGIVVGVNSFTLDGNKDAIAEAKSILQKKNATYPNITFASDSEAGKFVKNIMAFPTTVVVDRDGNIVGDPILGSVAEGSGKKALEERIEQALKNDANKDAAYKENTKK
>NZ_LT632322.1|WP_071705211.1|645843_646335_+|mechanosensitive-ion-channel-family-protein
MIDIDFIQFNMAEMGALVDCMTPTGRYVSFPNRFIFQEAVFNYNRDDPFVMQDVFVLIDGKEDRQKALEIAGKVAYEKYQNIIADYDEEEMQHFENAVGAMSGDAKPKIRATLDPNGVRIYIQFFTAYDEIGKNKMIMENALYDALLANGFTFPSPQYIRLLK
>NZ_LT632322.1|WP_071705210.1|645450_645837_+|mechanosensitive-ion-channel
MQQYFEYLRDIGDDQHSFLEKIAVSVLIFLAIFVVRLLVAKCLDGVVKDEKRRHRILSATRFFTVLLTIYLVLYVWFSRAKSVGLIVGIGLALLVLALKDLIMDIFAFIYIFLRRPFAVGDLVEIQGI
>NZ_LT632322.1|WP_071705209.1|644882_645311_+|hypothetical-protein
MTLFLNEEDMHKNLAELLPEGETYQVQIWGLLLGGSSLERFILGKMATLNNVCTYLGVTEKHLVMALMGTVSISQRQGELALPLDEIDQVQVKHSFLPGKSTVILQVGQEKIKLSLMSRNPVTASIKNQKEEIATFCSLLAK
>NZ_LT632322.1|WP_071705208.1|642316_644587_+|ABC-transporter-permease
MRNPMNKRIPRMLLHQPAHYVPLFLLLLITIIFCSAFFLVQGSVERLYYDFMDRSHVEDGRFTTLSPLSDATWKRVEEKGVQLEKNYYIEAKDGDADLQLYAVRRKSNVPDVIAGRLPEKEDEVALDVNYVREHAYALGRDITISGRSMRLVGTVVLPDYIAMLHTRSDLVMDTKNFGVGIVSEDGLLRFPQQSLQYNYSYRENKTSATKKEANDTLKELTKTVYEDNILTEAMTQAQNKRISYMMDDMGGDVPMMRMVLILAVASIAFVFTMQTRNQILSEASAIGTLMASGYTRRELIVHYMLLPTVAVLSAAVLGNLITYTVGYKLYMNLYYDSFSLPVFHPLFNARAFLLTTVIPAVIVTLIQFLMLMTKLRLRPLRFLRHELGRKPRVSKMRLSRFAFFSRLRFLSRYRLKVLFNNKLNVLVLLFGVTLSSIFLCYGLGMRPIFERHADLMQKEFPAKVQTFVRPGTVLDAADEEAEKFGYAAFDLSINGDVHPFALYGVAPDSRYFDAQAIDPLRDKEIQASEGLMKRFGLVEGDNITVVNPYTGKTYTFCIRAMRRQAVTLSAYMPLAAFNAVMGYDKDAFSGYYSEHKLSLDPASVVSCIDLDTVGKASDHFLDTFGQIIGPIVIIAVLFYFIFIDFLSKAIVDKAKTEIAYLKIFGYTDAETTGIYLRATGILLGLFLLVLPFLLRFLLAILLTAALAKLDSYMDPHVPMQIYFLVSVTGAVLFFLVQALQKRKIAKISMTETLKEV
>NZ_LT632322.1|WP_071705218.1|652511_652730_+|cation-transporter
MKKTYAIEVDCANCANLMEEAANKTSGVEKANVNFMMQKMTVHFADGADANDVMDEVYKACKKIEPDCSIEY
>NZ_LT632322.1|WP_071706074.1|653557_655510_+|cadmium-translocating-P-type-ATPase
MPKKQRIMLKRILASAVLLFVLELLPAETFATLDASLFSGAGRGLRLALYVVDYGIIGYDILQKALQGMRNKRLFDENFLMAVATIGAMTLAIIEDGDYLEAIAVMLFYQIGEWFQRYAVGKSRRNISALMDIRPDYARIERDGEWIKVDPDEVPVGSHIMVHPGEKIPLDGVVMEGTSSLNTAALTGESLPRDVHEGEEVLSGCLSMTGVLTIRTTKEFEQSTVSKILDLVENASSRKAQSEEFISRFARVYTPAVCGAALALAVLPPLVRLFFLHLPAAWMVWIYRALTFLVISCPCALVISIPLSFFAGIGGASRAGILVKGSNYLEMLSKTGILVMDKTGTLTQGVFEVNALHHAICEEERLIELAALAESASSHPISKSLLRAYGKKIDTDRVTNIRELSGKGVLARVDGIEVAAGNDKLMEHLGVEYQNCHMTGTIIHMALDGEYAGHIVISDRLKPSAPKAIRALKSVGIHHMVMLTGDSDKVAQEIAQKLGIDEVVSELLPDGKVENVERLLQTKRKGEQLAFVGDGINDAPVLALADIGIAMGAMGSDAAIEAADVVLMDDDPMKIAQAMRISRHCLGIVKQNIVFALAVKFVCLSLGALGLAGMYLAIFADVGVMILAVLNAMRCLRVGGDDTVSALSVR
>NZ_LT632322.1|WP_071705220.1|655554_656508_+|L-lactate-dehydrogenase
MTHRVDNRKVAVVGCGFVGSSSAFALMQSGLFSEIALVDVNREKAEGEALDISHGVPFVGQVKVYAADYADIMDAAIVVVTAGAAQKPGETRLDLVNKNIRIFQSILPEFKKRNYGGILLVVSNPVDILTLAALELSGLPEQRVIGSGTVLDTARLKTALGEHLDVDSRSVHSFIIGEHGDSEMVAWSSTNVSGIPLNDFCEMRGHFSHDEAMERIADEVRNSAYEIIAKKHATYYGIAMSVVRICKAIVMNERSILPVSTMMHGEYGIDGICLSMPVIVGEEGAGVHVPLVLNDEEQEKLLASANALKEVARSAGL
>NZ_LT632322.1|WP_071705221.1|656586_657813_+|MFS-transporter
MLQLLLVLIYFAFISLGLLDALLGAAWPSLYPSLGVPISYAGVISMIISAGTIVSSLLSDRLHRRFGTGRITAFSVSLTAIALFGFSFSTSFIQLCVWAIPYGLGAGSVDAALNNYVALHYESRHMNWLHCMWGIGASLGPYLMGLCLTHGWGWASGYRSVGAIQVVLSAVLLFTLPLWKKAEGPRAAATSVGATSKEKSAPASGLSAILSLPGAKAILLCFFCYSALEATVGLWASSFLSLAIGVDPKVAAGFAGLFYLGITGGRAASGFLSLRFDDDALIRGGLLTIGLGLVFLGMSLFCGMLWANPAASLPPMLALIGLILMGLGCAPIYPGIIHSTPAHFGEERSQAMIGMQMACAYVGSCFLPPLFGMLARSVSVALLPLYVFLLLALMGFMHRRVVRATAVR
>NZ_LT632322.1|WP_071705222.1|657915_658782_+|radical-SAM-protein
MQYIGDVYRPPSEASSFILQCTVGCAQNTCRFCSMYKKDSFFMRPQEDILADIAEVAMHWPALRRIFLADGDALVMPTPRLVEILETAHRHFPYLERATAYATVRDVLAKSDADLQQLRALGLTMIYLGLESGSDEILQRIDKRQTQADYVEAVLKAKRNGIDSSVTLIFGLGEQELSELHINESAKAISLSKPAYASFLSLHLSPGAPLYDDVKEGRFKLLSDEEILDEMKRFIEKVDSEGTIFRSNHASNPVPVGGTFNRDRAHMLQQIEEARRWQAYRPRAWRDI
>NZ_LT632322.1|WP_071705223.1|660077_662054_+|DNA-polymerase-III-subunit-gamma/tau
MQKALYRAYRPQTFDEVVGQDAIVTALKNQVTTGHVGHAYLFSGTRGTGKTSCAKIFARAVNCLDSQEGNPCNTCAHCRAILEETTMDVVEMDAASNRGIDDIRELRETVIYPPAQVRYKVYIIDEAHMITKEGFNALLKIMEEPPAHLIFILATTEPEKIPATILSRLQRYEFKRIDVEVITRRLSYIAEKQGITITPEALTALARAADGALRDALSLLDQVMAMGETDITEELVDQVLGTAGKLSLAQLTRDVLNDRMTAAMTHAASLLQEGKEAAVLLREWIAYFQQLLLIKGAGKEWKAPISEMERQEMESLVADVPMARLLDSVDHLVETDALLQKSDHADTLFLAAVARLINYASPRVLESRIAALEQKLSMVERWQSPEKAIRDAMDRLQAVAPVAPQAVAPASKELPEKEPSASKSVAQPAFKPVAPPKQATHPQEAVQPASKPVAQPEQKPVAPPQPTDFTAPSASSDSFSADPEAWYRRNEDAWRSAVEKEKIVPTFFLGSFDRIDVQQGNAYITYARENEAKGTLLKAKEAELSAAFSRFAGETIRLHFGEEAPARRPSSDTTEPTQSKDRTQPEDGKQSKDRMSTSTKPVTVPTTAESITPSAEMATDKGHAPTSMPGDEPTEPESDWTWQELQRTIPKEILKKME
>NZ_LT632322.1|WP_071705224.1|662063_662399_+|YbaB/EbfC-family-nucleoid-associated-protein
MKGFKGPRSGNNMNNMMKKMQRLQRQMEETQQKIDATEIEASAGGGVVKVKMNGKHELLELVIDPEVVDPEDTEMLADLVMVAVNDAIQQASALNESEMGRLTGGMNIPGL
>NZ_LT632322.1|WP_071705225.1|662458_663079_+|recombination-protein-RecR
MNEFPASVEVLIERFRQQPTIGKKTAQRLALHALKDPAATRAFARALLDVTEKVHRCRICGNITEETICPICASAKRDHSVITVVEDVTNLLAIERGAAYFGTYHVLDGLLSPMDQRGPEDIGVHRLLQRIKDSMNSETPVKEVILALSPTVEGETTMLFLADQLEAFPVRVSRIASGIPVGGSLEYYDELTLARAMEDRRAMNER
>NZ_LT632322.1|WP_071705226.1|663083_663842_-|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MKPIIGLSTTYTHNDQLGPMLHMGVAGQSYHVCTDDFVRAVSVAGATPVLLPTVDTDEEREALLDVLDGIIFCGGADLYTPLYGESTEKTCGPVVPEQDHHEASLARLAKKRHLPILGVCRGMQLLNIAFGGTLYQDLPAQKPSTLYHSIENVPREYGVHALEIRPHSLLENLLGESTWVNSFHHQAVKDVAPSLSACAQTKDGVIEALECPEMPAFLAVQWHPEMMAAKNDAQQAIFSWLVTCAREFVGRK
>NZ_LT632322.1|WP_071705227.1|663972_665250_+|alanine-racemase
MKAQSILEVNTTKIRENLLAMRKGHPQEIFGVVKADAYGMGAVRVANALREDVVGFCVATVSEALTLRRTIADKPILLFGYTDPDDRPELIRRGIRPAISTLADAEAWNREAEKVGICAPMHIALDTGHRRIGFVTESEEAFADICAAVKLWHLRIEGLFSHFATADEAPFPHPFAQEQLSRFRRMAERLEAAGISIPFRHIANDAGLLFFPDEELFDAARLGICLYGHYPSKESEAACDIDLQIPYRWTAPISRVKWMDENESVGYGRTWFSKRKTKVATVQVGYADGYPRILSGRAMMLVKGVACPVIGRICMDQLMLDVTDAPPVDVGDRVLVMGAADWEHTDSRAIRKASERAFATLFGDASAMAEKETTTVATRHDGEGLSSGRKNLPGISADSLADRAETISYELLTAIAPRVYRVEVK

Crispr_ID: NZ_LT632322_6

• CRISPR_ID: NZ_LT632322_6
• CRISPR_location: 935971-936065
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT632322_6

Consensus_repeat	Method
CAACGGATACGGCTATGCCAGTG	CRISPRCasFinder

spacers of NZ_LT632322_6

>6.1|935994|49|NZ_LT632322|CRISPRCasFinder
GAGGAGACGGGCCAAAAGAGTCCGGGTGAGATAACAGAAGCCCCTGAGC

CRISPR arrays and Neighbor proteins around NZ_LT632322_6

CRISPR arrays

The CRISPR arrays of NZ_LT632322_6

>merge|NZ_LT632322|6|935971-936065|CRISPRCasFinder
CAACGGATACGGCTATGCCAGTGGAGGAGACGGGCCAAAAGAGTCCGGGTGAGATAACAGAAGCCCCTGAGCCAACGGATACGGCCATGCCAGTG

>NZ_LT632322|6|5|935971-936065|CRISPRCasFinder
CAACGGATACGGCTATGCCAGTG	GAGGAGACGGGCCAAAAGAGTCCGGGTGAGATAACAGAAGCCCCTGAGC
CAACGGATACGGCCATGCCAGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl|CDD|225174
NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump	unknown	unknown	gnl|CDD|308338
NZ_LT632322.1|WP_071705432.1|927875_928862_+|Abi-family-protein	unknown	unknown	gnl|CDD|377910
NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|224877
NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NZ_LT632322.1|WP_071705436.1|931628_931832_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein	unknown	unknown	gnl|CDD|273011
NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase	unknown	unknown	gnl|CDD|180840
NZ_LT632322.1|WP_071705431.1|926691_927651_-|DUF1002-domain-containing-protein	unknown	unknown	gnl|CDD|377628
NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase	unknown	unknown	gnl|CDD|376623
NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein	unknown	unknown	gnl|CDD|377306
NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein	unknown	unknown	gnl|CDD|273267
NZ_LT632322.1|WP_071705443.1|943221_943542_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase	unknown	unknown	gnl|CDD|238986
NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224058
NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|378823
NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein	unknown	unknown	gnl|CDD|274737
NZ_LT632322.1|WP_157885033.1|925799_926606_+|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl|CDD|376614
NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase	unknown	unknown	gnl|CDD|235073
NZ_LT632322.1|WP_071705433.1|928874_930158_+|hypothetical-protein	unknown	unknown	gnl|CDD|273659

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase	gnl|CDD|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	8.92466e-86
NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump	gnl|CDD|308338	pfam02659, Mntp, Putative manganese efflux pump. MntP is a family of bacterial proteins with a signal peptide and four transmembrane domains. It is a putative manganese efflux pump, since deletion of the gene leads to profound manganese sensitivity and elevated intracellular manganese levels in bacteria. Manganese is a highly important trace nutrient for organisms from bacteria to humans, and acts as an important element in the defense against oxidative stress and as an enzyme cofactor.	2.22248e-43
NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein	gnl|CDD|273011	TIGR00320, Desulfoferrodoxin_homolog, desulfoferrodoxin. The short N-terminal domain contains four conserved Cys for binding of a ferric iron atom, and is homologous to the small protein desulforedoxin; this domain may also be responsible for dimerization. The remainder of the molecule binds a ferrous iron atom and is similar to neelaredoxin, a monomeric blue non-heme iron protein. The homolog from Treponema pallidum scores between the trusted cutoff for orthology and the noise cutoff. Although essentially a full length homolog, it lacks three of the four Cys residues in the N-terminal domain; the domain may have lost ferric binding ability but may have some conserved structural role such as dimerization, or some new function. This protein is described in some articles as rubredoxin oxidoreductase (rbo), and its gene shares an operon with the rubredoxin gene in Desulfovibrio vulgaris Hildenborough. [Energy metabolism, Electron transport].	3.55431e-37
NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A	gnl|CDD|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	2.55125e-55
NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase	gnl|CDD|238986	cd02028, UMPK_like, Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK).	7.31042e-52
NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	8.61148e-69
NZ_LT632322.1|WP_071705432.1|927875_928862_+|Abi-family-protein	gnl|CDD|377910	pfam07751, Abi_2, Abi-like protein. This family, found in various bacterial species, contains sequences that are similar to the Abi group of proteins, which are involved in bacteriophage resistance mediated by abortive infection in Lactococcus species. The proteins are thought to have helix-turn-helix motifs, found in many DNA-binding proteins, allowing them to perform their function.	3.9096e-41
NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase	gnl|CDD|180840	PRK07105, PRK07105, pyridoxamine kinase; Validated.	3.95751e-84
NZ_LT632322.1|WP_071705431.1|926691_927651_-|DUF1002-domain-containing-protein	gnl|CDD|377628	pfam06207, DUF1002, Protein of unknown function (DUF1002). This protein family has no known function. Its members are about 300 amino acids in length. It has so far been detected in Firmicute bacteria and some archaebacteria.	4.22419e-51
NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase	gnl|CDD|376623	pfam01817, CM_2, Chorismate mutase type II. Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.	1.7222e-18
NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein	gnl|CDD|377306	pfam04326, AlbA_2, Putative DNA-binding domain. This family belongs to the AlbA clan of DNA-binding domains.	5.769e-13
NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein	gnl|CDD|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	7.81918e-17
NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein	gnl|CDD|274737	TIGR03709, PPK2_rel_1, polyphosphate:nucleotide phosphotransferase, PPK2 family. Members of this protein family belong to the polyphosphate kinase 2 (PPK2) family, which is not related in sequence to PPK1. While PPK1 tends to act in the biosynthesis of polyphosphate, or poly(P), members of the PPK2 family tend to use the terminal phosphate of poly(P) to regenerate ATP or GTP from the corresponding nucleoside diphosphate, or ADP from AMP as is the case with polyphosphate:AMP phosphotransferase (PAP). Members of this protein family most likely transfer the terminal phosphate between poly(P) and some nucleotide, but it is not clear which. [Central intermediary metabolism, Phosphorus compounds].	1.09393e-147
NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.34824e-149
NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein	gnl|CDD|378823	pfam12161, HsdM_N, HsdM N-terminal domain. This domain is found at the N-terminus of the methylase subunit of Type I DNA methyltransferases. This domain family is found in bacteria and archaea, and is typically between 123 and 138 amino acids in length. The family is found in association with pfam02384. Mutations in this region of EcoKI methyltransferase abolish the normally strong preference of this system for methylating hemimethylated substrate. The structure of this domain has been shown to be all alpha-helical.	7.68199e-11
NZ_LT632322.1|WP_157885033.1|925799_926606_+|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl|CDD|376614	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.	7.00442e-72
NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase	gnl|CDD|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_LT632322.1|WP_071705433.1|928874_930158_+|hypothetical-protein	gnl|CDD|273659	TIGR01499, Folylpolyglutamate_synthase, folylpolyglutamate synthase/dihydrofolate synthase. This model represents the FolC family of folate pathway proteins. Most examples are bifunctional, active as both folylpolyglutamate synthetase (EC 6.3.2.17) and dihydrofolate synthetase (EC 6.3.2.12). The two activities are similar - ATP + glutamate + dihydropteroate or tetrahydrofolyl-[Glu](n) = ADP + orthophosphate + dihydrofolate or tetrahydrofolyl-[Glu](n+1). A mutation study of the FolC gene of E. coli suggests that both activities belong to the same active site. Because some examples are monofunctional (and these cannot be separated phylogenetically), the model is treated as subfamily, not equivalog. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	5.30613e-75

Protein sequences

>NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase
MTDLTVDGRGIGHLKAQDVLFAPHGTVPLPEEDVGRTVFVYGALPGDVVRLRVHKRKKNILEAQAMELLTPSPGRRPISSHPHAENSHTGFLPDEPEDDAMTPHDGFPLLAWDPTEQKAWKMRRVREALVRVGGFAASDLPEMDWIAAEETHYRNKINLRLTPDGRLGDTARDGKVRPLSSYVIAAPILEQKLQQWNVLALQTPNWAKTFSAVRMVVLRANEKGETLAALITDPLSSAQRKALFALLQPLSFTVLCQGQNHRPGDVRLREPLVYATPQKTLQTTLSGLSFTVSPPSFFQVNRFLTPALYAKALSFFSDLPDATVLDLYCGTGTTSLLLAQQAKRVIGVEMVEAAVEDARQNAARNALTNVSFIAAKAEEILPSLTADFAEKSLCVLVDPPRKGLDESVRRSLFSIELHELVYISCYPETLARDLRDFRQQGWMLDRLCVADMFPNTPEIETVVRVRRR
>NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase
MKITKQARQRAKELLQFIDGSPTAYQATEQEKALLDKAGFTPLSLTSRWKLEPEKTYYVEISDATIFAFRTAKQADAGFHIIGAHNDSPGFQLKQNVNMPRNGYGQLNVEPYGGLILRTWLDRPLSVAGRLLVKDDSPRGYSVKKIHITRPLLIIPSLAIHMDREVNKNGEIKPQNGMAPIWCMADEPDKKGDFLAVVAQEVGIARESILDADLFLYDVQKGMFLGENEEFLSVGRLDNLAMCHAATTALTKANPADVHQVIALHDHEEIGSMSRKGADSATLRDVLSRIVRSLGGDEEDFAVALAKSFTISCDMAHAIHPNHTDCADPTNRPLLNHGPVLKYAASKSYITDGEGGARVRLYAKKAGVTFQTFHNHSDKRGGATIGAMDEQWTTILNADVGNPVLGMHSVRELGGVADHDAMIRTLTAFLNDEK
>NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump
MTFFELLLLAVGVSLDAFSVAICKGLAVQELHVRHGLVVGAYFGGFQGLMPLLGFLLGSWIAQSMRAIDHWVILLILGYLGIQMVREARNPESCPTGDFSWSTMFPLAVATSIDAFAVGVTFAMMEIDLWMAIPLIAVCTGLFSFAGVYIGHYFGQRYQKPAGIVGGAILLFIGLRVFITHWIQGI
>NZ_LT632322.1|WP_071705436.1|931628_931832_-|hypothetical-protein
MLKTKYIVQYQGREVDMEELVKQAKMYWKQDGHKLSELKTLDIYVKPEEYAAYYSINDEEQKGRIAF
>NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein
MDFYYCEHCGAMYIKANQVGKVTPVCCGEPAKKMEANTKDAAVEKHVPAVTREGNKISVVVGEVVHPMEEDHYITMIAVVQGDKFQSVALKPGQEPKAQFLVEDGPVTVYEHCNKHGLWKAEA
>NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA
MQSPAQKRRSAMVRYISSYWMENGIAPTVREIQEALGIRSTSTVSKDLHALIDAEQITMTKGSYRSIRPVEDLSVQETQDTPYREDVLDIPVYGAVAAGQPIYADDYTEESIPLPTAFFHQDGSDYFILKIHGESMIEAGIFDGDHVIVRRQQTARNGQQVVALIEDSATVKTFFQRAGYVELRPENAALEPIIVKECRILGVVCGLYRLY
>NZ_LT632322.1|WP_071705433.1|928874_930158_+|hypothetical-protein
MRPQKEWNALQKATYCWLEAFDHPEKNKCIIHLIGTNGKGSTGRTLALALEKLLPEKVGHFVSPHVHHYEERIMLQSQPITHERSVAIQQAMEEKGKAENLPYIPYFARSMVEALLAYREEARVLVMEAGIGGLDDCTNLLSTAMTVFTTIDFDHRDRLGNTIQEIARAKAGVLLPGSFAVSADQRPEAETVLRNTAEAKNASLVFYSPQTITDAALRWQKGERPALHFTFTRGALSGAYAARLIGRHQLQNFGTALTALEEMLAPDSPVAAALFPTGQLPRPEKIDEAVHAAVAEAYLPGRLEMLSYDPMVFIDGAHNHQAAKMLVENLDALSSCSPAKGKERVLLFGMHDGKLSEKEQQEFFAAFDAVYRIPVQDEEDDAVIEAMGKALDAAYLAHPNALFVAAGSLYLLDGASRWLEKAPSRKK
>NZ_LT632322.1|WP_071705432.1|927875_928862_+|Abi-family-protein
MSVQLMHSDAKLYDMVVNDKLIIRDMDYARKVFQRVSPFHLENFGLTWKKADGTYREGTTLEMLVDSYLADRRIKNFLFDYLSDYEVQLRHVLGTVLLESFGEYGYLDSGHFRQDEYHKNFINDLENELTRANEPFVRRFCPEEGKTREVPVYVAMEVITLGTLTKIFNNMRRPEQKRVSAFYGVLSENVLYSFFTCLSKLRNTCAHHGRLSNRRFSEGCAVLKEDKCVMEKLAPTYQPDAFRFFAMMLALMHLMDAQSNREIIVHYQRTFTLHPHFSPRFLDFPEAWEAILCAAANIDIASLHSKDISEEPIASDRWVMPPSKRSEQ
>NZ_LT632322.1|WP_071705431.1|926691_927651_-|DUF1002-domain-containing-protein
MKQKKTLCQRFFATVLTLLFALTSLAQPAKADNLKQSVYSYGQSLTAEQKQETARLLRVSDKALEMQVNIDEMNSLLHDHYDYYQVYSSVYLEPTDKNTGVKVEIVTPKTITSITATQYANAAITAGATNMTIRVASVKAVDGSGALAGVYKAFSGTTGTLPEENVKTAQEELEITSKINEENKGKDGYSDELLNAAIAEIKAQIAKEKEKNGGNISVGDITTIINTVVNNYHLDGVLSAENISSLQGLMENFSKIRLTDEQIANLRNLGENLLKQGGNLMEKVQTDWAHLSPETKTELGGFFGNLFQGIIDFFSNLLK
>NZ_LT632322.1|WP_157885033.1|925799_926606_+|Nif3-like-dinuclear-metal-center-hexameric-protein
MQIQKWVEEWEKRVPLTLQEAWDHSGKQFGRFAQPLRGVVFALDFSAGALQKAVEMGANLLVTHHPVLFEGVHTLHEDVPLQNLVMRALEQGIAVYATHTPWDWVDGGVNTEIAERMALRECRALRPREEIDPQRAYSAGFGVYGNIEPMTLAAFARNLSQAFSTPSVVFYGEGERNITRVGLLGGSGMDFMPDALTAGCDVFVTADIKYHEAQSALQNGLALIDLGHYAAEFPSMARAMRLSQSFAPNVPQEVFDEKENKRHSLSGE
>NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein
MVVKNTANIGFERQIWDAACVLWGHIPASEYRNVIIGLIFLKYISTAFDKKYKQLIADGDGFRNFA
>NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein
MYTPIHRELGLPASIPLDWSLMQRVVEAKMHEQRDLDFKMIGYNSQDPHSASELAKDLCAMANSGGGWIICGIRTDPKKDIAEELTPFTIDKNTDQNIYRIAWTNVQPSLSEVKIHAISSPDEKWIYAIEVPPSELFPHLCLYQKGNESYPFYAPIRNGSSTVGLTEPELRRLYRESYQLKKDKEANEKQLYDEFAEYGQIYDGLTFIFMGIPEYLVENRLDQVTINQSLDGIKTNQYRYDNNGLWLLRNFGDEFARSRRGLRSWVLRNERDMDQHRFWRLELKDNGILRIAIQLGGWIGCEDWSEYPAGTKNQASQRFIEDALVEAYAFLVKCQQKWHPYTYKITAGLSGPAEMPLIIRGVASWYGGDRASLMPESTSKRIYHFKPITSYLDINADDKERLQVLNSLGEDIINQGEISHLQSIIAE
>NZ_LT632322.1|WP_071705443.1|943221_943542_+|hypothetical-protein
MTKENKIVEKAPFQERWEAFKKAYYAWAKYNPYKEYPYPRYEDFRQEEFDVQKLPEHFIEKVHYYDEVYRIATIRHREALRRRKINIKAKKIRLRYELKQAFCNLF
>NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase
MCTMRLYTRREGEEVAVSKETTFAECAQKMEEQAQGRIVLARVKNHLFELAQPIPEEAEEVVLMDTTDSDGYRVYMRTLSFVFLEAIERLFPDTHTVIEHSISGGLYCVLHRKGHVFMLDTRQRDELKAEMRKIIEADMPIVRENMTYEEAKQLFRTLGRADKVELYAQQTGNHVAVYRMGNAVDSFFGYMAPSSGYVTVFDLELFDHGLVLLGVDRQDKTRVNNFVPTYLLSDTYNEAEDWADRQGIYTVAQLNRSIQNGTIGDVCRMNEALQDHKIMHIAENIVLKNKRIVLIAAPSSSGKTSFAYKLMTSLRVLGKRPVAISLDDYFVDRENTPLDEQGEPDFEALEAIDLRTFNADMRALLTGEEIERIRFDFVAGKRVHTEERIRLGAEEPILLEGIHALNPKLSSDVDNRYKYRIALSVITQINLDAHNRIPTTDLRLMRRMARDLQFRGRDVRQTIRTWPDVRRGENRNIFPYSELADVMFSSSFVYEIAALKPILEPHLREIGEDEPERIEAVRILSLLQYFLALTDTSDVVNTSILREFIGGSKLVH
>NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase
MKQQPQKSAPTPRILTMQDISCVGQCSLTVALPILSACGMETCVLPSAVLSTHTGFSTFTFRDLTEDIPSIMENWKQQGLLFDALYTGYLGNVQQIELVKELAQNVLVPGAKTYIDPAMADHGKLYVGFDSAFVDAMKTLLPIADVLLPNITEACLLTDTPYREEGDAAWMHTLAEKLLAFGTKNVVLTGVSTKPDTTGVLVMGEAGEEWYTHALLTPGSHGTGDIFASVFVGAHVRGKSLGEAARLAADFTCLALEETHKDPDHWYGARFEPVLGRLVKMLEA
>NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein
MSEQKTLDTKRYLVDGDTFSLAKHDPGDRQGWKKKEGQAALHANQEEMFILQQKLYAENKQALILVFQAMDAAGKDGCIKHVMRGLNPQGTHVVSFKQPSSEELDRDYLWRINRALPRRGEIGIFNRSHYEEVVVTQLHNLVENQQLPDFVLEKPIWKERYRQIGDWERYLYEQGYHIVKFFLHISEEEQRQRLLARIEEKDKNWKFSAGDIAEREHWDEYQKLYEKALQKTSTKACPWYVIPADHKWFSRLLVSQIVRETLEQMDPQYPRLSPEEESRLGEWREVLESQA
>NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A
MITFLCGLLILVLGGAVYALFIERLFSPDDRLTPAIARADGIDFTGMPTWKNALIELLSITGTGVILGSIQAVLFGPIAFLLIPLANIFGGAVHNYLTGMIAMRNRGMQMPGLVEKYLGLGVSRIFLFLLMALLFSTGVVLLYTTGDYIGQSFPTSLSREAGLYLLLYVGLLVYFIVTTLFPIDRTIGRIYPLFSMVLFVTTLALFLGILRDGLGSLPEITKVTAIPSLGQGRVLPVFFITLAHAILSGLHASQSTLVARTVCKESDGRAVFFYTMLAEGFLSMCWAGGAMILLARHPNLVNTLEPVALVGAVSREFLGGWGDFFALLCLFVLPITTGDTVFRAIRLIFGELFHVNQRLPWKRFVTTVCVFLPALFLLVLAKTNIYGFSRLWRYYGFLSQVVATFGLAMASVYLHAHYKNYWVAFLPMLATCFIATSYILHAQGGLQLDALLGNPESYRASYTLAFLFTLLIGMLVRRHAVEHSHAIRIREEER
>NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase
MATSKKSTKSSEQKSNAALASSSSDTLESLRRQIDAIDRQMARLFEERMRLSRTIGAWKKATGKPVRDEKREAEMLASHRQWIKDVSLRESYGTFLQGILQLSRDTQHHDLLEQRDHEEGDCP
>NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein
MQNTSLRRKFWIGCSLALMLLFHFLPPFSGMSESAMTVLGLFIGVLLLWLFVAIDWPSLVLLAGLMTVPEWKTADVFAASFGSPTVLCLLFTFVLTHALAETGVLRRIAVAFITCRPARRGPWHFVALYFAGILFLGSFISPTVLFFLYLPMLEEMYAVLGLKKGDPAAALLMMGTVIMTGISSGMTPIAHVFPLIAMNAYEVYAGVPVSVGRYLLLAVPVGLVTAAGMLLLFRLLLHPDPNAFHPDRAERLKERLFQEKNAEEVSTVDSLDERALTSQYTDGQMHRARKVVGVFLFVLFLWIAPDLLVRLIPLQGVQQLFSTLHRLGPAFPPLIGCVMLALFSDDGKPLLYLDKAFREGIAWPAILMCAGTGALGWALTQPTIGWSDWLAAHLSSLASSFSPALLFFFFALWASLQTNLSSNMVTATVVSAAAIGALPQLLGISGELLLSMIGMLSAYAFATPPAMPCVAIAGSSGWTTTRQMMRYGFLAMLIGVVVASAWACCLNALFLG
>NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein
MIRVEHVSKEFSADNGVLHAVRDVSFEVGEGEIFGIIGLSGAGKSTLVRLLNRLEEPTSGHIAIDDVEVTKLNAQELLQARKEIGMIFQSFNLFRQKSIRKNIAYPMQIAGWSKEKTKARTDELLQFIGLADRANAYPSELSGGQQQRVAIARAMALQPKILLSDEGTSALDPKNTASILELLRDLAQTYKTTIVMITHQMEVAKEICDRIAVMADGEIVEMGTTRDLFFQPKHSVTKSFISKLQDADEFGFLRNREFAGDVVKLTYRKETIQHSLIADVLKQFPVGISILSANIDTFRQGEIGYTIIELTGQEADRMCALDAFRKQVDVEVMK

Crispr_ID: NZ_LT632322_7

• CRISPR_ID: NZ_LT632322_7
• CRISPR_location: 943638-943784
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT632322_7

Consensus_repeat	Method
CGAAAAAAGGAGCCTAAAATAC	PILER-CR

spacers of NZ_LT632322_7

>7.1|943660|40|NZ_LT632322|PILER-CR
AAAATTGCAAGGAAGGGCTCCTTTTTCAATGTCCATAACT
>7.2|943722|41|NZ_LT632322|PILER-CR
AACATAGCAAAAAAAGGCTCCCGCTTTTCGCAAAGAAAAGA

CRISPR arrays and Neighbor proteins around NZ_LT632322_7

CRISPR arrays

The CRISPR arrays of NZ_LT632322_7

>merge|NZ_LT632322|7|943638-943784|PILER-CR
CGAAAAAAGGAGCCCAAAATCCAAAATTGCAAGGAAGGGCTCCTTTTTCAATGTCCATAACTCGAAAAAAGGAGCCTAAAACACAACATAGCAAAAAAAGGCTCCCGCTTTTCGCAAAGAAAAGACGAAAAAAGGAGCCTAAAATGC

>NZ_LT632322|7|2|943638-943784|PILER-CR
CGAAAAAAGGAGCCCAAAATCC	AAAATTGCAAGGAAGGGCTCCTTTTTCAATGTCCATAACT
CGAAAAAAGGAGCCTAAAACAC	AACATAGCAAAAAAAGGCTCCCGCTTTTCGCAAAGAAAAGA
CGAAAAAAGGAGCCTAAAATGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl|CDD|225174
NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein	unknown	unknown	gnl|CDD|273011
NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A	unknown	unknown	gnl|CDD|224877
NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase	unknown	unknown	gnl|CDD|238986
NZ_LT632322.1|WP_071705436.1|931628_931832_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705450.1|952745_953390_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224922
NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase	unknown	unknown	gnl|CDD|180840
NZ_LT632322.1|WP_071705439.1|935846_940367_+|Cna-B-type-domain-containing-protein	unknown	unknown	gnl|CDD|377553
NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA	unknown	unknown	gnl|CDD|234688
NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase	unknown	unknown	gnl|CDD|376623
NZ_LT632322.1|WP_071705451.1|953475_954345_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270315
NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein	unknown	unknown	gnl|CDD|377306
NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein	unknown	unknown	gnl|CDD|273267
NZ_LT632322.1|WP_071705443.1|943221_943542_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071706103.1|954572_956174_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238733
NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224058
NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|378823
NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump	unknown	unknown	gnl|CDD|308338
NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase	unknown	unknown	gnl|CDD|235073
NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein	unknown	unknown	gnl|CDD|274737

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase	gnl|CDD|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	8.92466e-86
NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein	gnl|CDD|273011	TIGR00320, Desulfoferrodoxin_homolog, desulfoferrodoxin. The short N-terminal domain contains four conserved Cys for binding of a ferric iron atom, and is homologous to the small protein desulforedoxin; this domain may also be responsible for dimerization. The remainder of the molecule binds a ferrous iron atom and is similar to neelaredoxin, a monomeric blue non-heme iron protein. The homolog from Treponema pallidum scores between the trusted cutoff for orthology and the noise cutoff. Although essentially a full length homolog, it lacks three of the four Cys residues in the N-terminal domain; the domain may have lost ferric binding ability but may have some conserved structural role such as dimerization, or some new function. This protein is described in some articles as rubredoxin oxidoreductase (rbo), and its gene shares an operon with the rubredoxin gene in Desulfovibrio vulgaris Hildenborough. [Energy metabolism, Electron transport].	3.55431e-37
NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase	gnl|CDD|238986	cd02028, UMPK_like, Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK).	7.31042e-52
NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA	gnl|CDD|234688	PRK00215, PRK00215, transcriptional repressor LexA.	8.61148e-69
NZ_LT632322.1|WP_071705450.1|952745_953390_+|ABC-transporter-permease	gnl|CDD|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	2.67252e-89
NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase	gnl|CDD|180840	PRK07105, PRK07105, pyridoxamine kinase; Validated.	3.95751e-84
NZ_LT632322.1|WP_071705439.1|935846_940367_+|Cna-B-type-domain-containing-protein	gnl|CDD|377553	pfam05738, Cna_B, Cna protein B-type domain. This domain is found in Staphylococcus aureus collagen-binding surface protein. The structure of the repetitive B-region has been solved and forms a beta sandwich structure.	7.35504e-32
NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A	gnl|CDD|224877	COG1966, CstA, Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms].	2.55125e-55
NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase	gnl|CDD|376623	pfam01817, CM_2, Chorismate mutase type II. Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.	1.7222e-18
NZ_LT632322.1|WP_071705451.1|953475_954345_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl|CDD|270315	cd13597, PBP2_lipoprotein_Tp32, The substrate-binding domain of the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum binds L-methionine; the type 2 periplasmic-binding protein fold. This group includes the lipoprotein Tp32, a periplasmic component of a methionine uptake transporter system, and its closely related homologs. The Tp32 has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus it belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	1.11897e-113
NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein	gnl|CDD|377306	pfam04326, AlbA_2, Putative DNA-binding domain. This family belongs to the AlbA clan of DNA-binding domains.	5.769e-13
NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	2.34824e-149
NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein	gnl|CDD|274737	TIGR03709, PPK2_rel_1, polyphosphate:nucleotide phosphotransferase, PPK2 family. Members of this protein family belong to the polyphosphate kinase 2 (PPK2) family, which is not related in sequence to PPK1. While PPK1 tends to act in the biosynthesis of polyphosphate, or poly(P), members of the PPK2 family tend to use the terminal phosphate of poly(P) to regenerate ATP or GTP from the corresponding nucleoside diphosphate, or ADP from AMP as is the case with polyphosphate:AMP phosphotransferase (PAP). Members of this protein family most likely transfer the terminal phosphate between poly(P) and some nucleotide, but it is not clear which. [Central intermediary metabolism, Phosphorus compounds].	1.09393e-147
NZ_LT632322.1|WP_071706103.1|954572_956174_+|VWA-domain-containing-protein	gnl|CDD|238733	cd01456, vWA_ywmD_type, VWA ywmD type:Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Not much is known about the function of the members of this subgroup. All members of this subgroup however have a conserved MIDAS motif. .	7.28443e-26
NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein	gnl|CDD|378823	pfam12161, HsdM_N, HsdM N-terminal domain. This domain is found at the N-terminus of the methylase subunit of Type I DNA methyltransferases. This domain family is found in bacteria and archaea, and is typically between 123 and 138 amino acids in length. The family is found in association with pfam02384. Mutations in this region of EcoKI methyltransferase abolish the normally strong preference of this system for methylating hemimethylated substrate. The structure of this domain has been shown to be all alpha-helical.	7.68199e-11
NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump	gnl|CDD|308338	pfam02659, Mntp, Putative manganese efflux pump. MntP is a family of bacterial proteins with a signal peptide and four transmembrane domains. It is a putative manganese efflux pump, since deletion of the gene leads to profound manganese sensitivity and elevated intracellular manganese levels in bacteria. Manganese is a highly important trace nutrient for organisms from bacteria to humans, and acts as an important element in the defense against oxidative stress and as an enzyme cofactor.	2.22248e-43
NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase	gnl|CDD|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein	gnl|CDD|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	7.81918e-17

Protein sequences

>NZ_LT632322.1|WP_071705443.1|943221_943542_+|hypothetical-protein
MTKENKIVEKAPFQERWEAFKKAYYAWAKYNPYKEYPYPRYEDFRQEEFDVQKLPEHFIEKVHYYDEVYRIATIRHREALRRRKINIKAKKIRLRYELKQAFCNLF
>NZ_LT632322.1|WP_071705442.1|941428_942712_+|ATP-binding-protein
MYTPIHRELGLPASIPLDWSLMQRVVEAKMHEQRDLDFKMIGYNSQDPHSASELAKDLCAMANSGGGWIICGIRTDPKKDIAEELTPFTIDKNTDQNIYRIAWTNVQPSLSEVKIHAISSPDEKWIYAIEVPPSELFPHLCLYQKGNESYPFYAPIRNGSSTVGLTEPELRRLYRESYQLKKDKEANEKQLYDEFAEYGQIYDGLTFIFMGIPEYLVENRLDQVTINQSLDGIKTNQYRYDNNGLWLLRNFGDEFARSRRGLRSWVLRNERDMDQHRFWRLELKDNGILRIAIQLGGWIGCEDWSEYPAGTKNQASQRFIEDALVEAYAFLVKCQQKWHPYTYKITAGLSGPAEMPLIIRGVASWYGGDRASLMPESTSKRIYHFKPITSYLDINADDKERLQVLNSLGEDIINQGEISHLQSIIAE
>NZ_LT632322.1|WP_071705440.1|940718_940919_+|type-I-restriction-modification-system-subunit-M-N-terminal-domain-containing-protein
MVVKNTANIGFERQIWDAACVLWGHIPASEYRNVIIGLIFLKYISTAFDKKYKQLIADGDGFRNFA
>NZ_LT632322.1|WP_071705439.1|935846_940367_+|Cna-B-type-domain-containing-protein
MKHIRNRVLAGAVALVMLVTAVITDSRPVLAEDKASSHAVETTDTAMPVEETGQKSPGEITEAPEPTDTAMPVKETGEKSLDERKEHPEETTEAITKAKTVEEGKETADAQAAQAKPEKALASANRSGVNYTFNANWSTKSTGDYSYPNNDPTSISVTSSNNTQKTVTWAVHLGVPQAQGANFPKGTVKITVPNFIVENWEQDGDTKRVNVDNNGNKLPHMTWQVAKAPEESTSIDFNYSDNGDGTYTLTNYKDLNGGFTFDFEQKFSFKPAFVKVDQNGKLQKDYAITLQIDADSNGKNEVDDTKKLSLQLQNRLKPGDVKLSVARKDNAKGAYLTWQKSWGPKPTDDDGKTYFYVIWFADYMRGSGTSLPFSATVTDTGTDGKVVGTGYFTWHDNTFQYPLNTTYPSIAKITESRTYRQYQGSETKALPGMPNYLNGHLVLQDMRPCLSQAILKRYPLSLLEGKSANDLRKKGVELSNSVQVDEIADNGQKDQVTAQATETVYFYLGEGSFGKYNVNNAETSLPMARTYLLDGETIRLAGNWNARDHSWHTSSVTRRPNTAKDQKWEMKITQSSPYYIEGKGNDLTNSTLNELFDQKKMTQLSDADYFYKDFYLTWTEYDAAQTHFGEDTGNPIRDYASYQPVEVWIRKKEQPAFEKYAQVKRGQDGAYIATDTNEKPLATSRRLNRTFWALPSDVAEIEYRHKNGENTFQTDMTTYENVVLRPTAAVKTLLAASKTAGNNSMVTAFAERTVGTMTDNTKGQPLAVTAYTLRDLSVSSSVFSKEGKLTDYPDESKQKRRVFDSNYNGAYAIFMDITGGGKSDKELVKRFAFNKGTFYDLLPKDTYVDPKTTELKLNWSYSDGVGNVIPKKNYSVSFVDDYEHSGRTMMIVNYTIPDDLLEFGGGDPRVVFSYDLYNTYENIVDRGTDVLHSVAFVNGNDKIPFHPGDAVKMPDKLADKNFFTNLGKSNAGKIMFNQATVHYQMVTVNQSGLTKKVKTANQPLYVESTTVEGKKVYTYRLRYQTQKGTNADQLVFYDVLDNGTTAKPSAWQGTLQSIDISAIEGKQSAGKDGGTLSPVVYYATTIPTQEQFDVDNGSIWSTTKPQDMKQVKAIAIDCRKAIKGTTDTNFVLEKGASLSVFVDLVAPTDPAFNEKKAVNSCTIKTRTFSGTEATASDTVRTLTAEAASDTVRRLTAAAASDTVRTLTADAEVTLKLVTTSLSGQKVWDDGADKDGIRPDAVTITLFANGKETGKTAKATKENQWKYQFDNLNIYDVDGKKIAYTVKEDPVPGYTTTVKDTTVTNTHNPVPRTSLTVQKVWKHVTPSFLKTASVEVVLYKNGQPTSTKVTLNEQNKFTWTFTDLLTADLLTGQPNQYTVKELDDKGQAADDGAKITLSNRRFTVKYATTGNQVTITNTHRFTPTPNPPTPEPPTPNPPTPNPPTPTPVEPTPAPKPQPKPTPTLPVKPQPKTGDSNRLLFWSALLGISVLSLTYLYAAKQKTKRKPR
>NZ_LT632322.1|WP_071705438.1|934034_935441_+|class-I-SAM-dependent-RNA-methyltransferase
MTDLTVDGRGIGHLKAQDVLFAPHGTVPLPEEDVGRTVFVYGALPGDVVRLRVHKRKKNILEAQAMELLTPSPGRRPISSHPHAENSHTGFLPDEPEDDAMTPHDGFPLLAWDPTEQKAWKMRRVREALVRVGGFAASDLPEMDWIAAEETHYRNKINLRLTPDGRLGDTARDGKVRPLSSYVIAAPILEQKLQQWNVLALQTPNWAKTFSAVRMVVLRANEKGETLAALITDPLSSAQRKALFALLQPLSFTVLCQGQNHRPGDVRLREPLVYATPQKTLQTTLSGLSFTVSPPSFFQVNRFLTPALYAKALSFFSDLPDATVLDLYCGTGTTSLLLAQQAKRVIGVEMVEAAVEDARQNAARNALTNVSFIAAKAEEILPSLTADFAEKSLCVLVDPPRKGLDESVRRSLFSIELHELVYISCYPETLARDLRDFRQQGWMLDRLCVADMFPNTPEIETVVRVRRR
>NZ_LT632322.1|WP_071705437.1|932701_934006_+|M18-family-aminopeptidase
MKITKQARQRAKELLQFIDGSPTAYQATEQEKALLDKAGFTPLSLTSRWKLEPEKTYYVEISDATIFAFRTAKQADAGFHIIGAHNDSPGFQLKQNVNMPRNGYGQLNVEPYGGLILRTWLDRPLSVAGRLLVKDDSPRGYSVKKIHITRPLLIIPSLAIHMDREVNKNGEIKPQNGMAPIWCMADEPDKKGDFLAVVAQEVGIARESILDADLFLYDVQKGMFLGENEEFLSVGRLDNLAMCHAATTALTKANPADVHQVIALHDHEEIGSMSRKGADSATLRDVLSRIVRSLGGDEEDFAVALAKSFTISCDMAHAIHPNHTDCADPTNRPLLNHGPVLKYAASKSYITDGEGGARVRLYAKKAGVTFQTFHNHSDKRGGATIGAMDEQWTTILNADVGNPVLGMHSVRELGGVADHDAMIRTLTAFLNDEK
>NZ_LT632322.1|WP_071706100.1|932074_932635_+|manganese-efflux-pump
MTFFELLLLAVGVSLDAFSVAICKGLAVQELHVRHGLVVGAYFGGFQGLMPLLGFLLGSWIAQSMRAIDHWVILLILGYLGIQMVREARNPESCPTGDFSWSTMFPLAVATSIDAFAVGVTFAMMEIDLWMAIPLIAVCTGLFSFAGVYIGHYFGQRYQKPAGIVGGAILLFIGLRVFITHWIQGI
>NZ_LT632322.1|WP_071705436.1|931628_931832_-|hypothetical-protein
MLKTKYIVQYQGREVDMEELVKQAKMYWKQDGHKLSELKTLDIYVKPEEYAAYYSINDEEQKGRIAF
>NZ_LT632322.1|WP_071705435.1|931100_931472_+|hypothetical-protein
MDFYYCEHCGAMYIKANQVGKVTPVCCGEPAKKMEANTKDAAVEKHVPAVTREGNKISVVVGEVVHPMEEDHYITMIAVVQGDKFQSVALKPGQEPKAQFLVEDGPVTVYEHCNKHGLWKAEA
>NZ_LT632322.1|WP_071705434.1|930221_930857_-|transcriptional-repressor-LexA
MQSPAQKRRSAMVRYISSYWMENGIAPTVREIQEALGIRSTSTVSKDLHALIDAEQITMTKGSYRSIRPVEDLSVQETQDTPYREDVLDIPVYGAVAAGQPIYADDYTEESIPLPTAFFHQDGSDYFILKIHGESMIEAGIFDGDHVIVRRQQTARNGQQVVALIEDSATVKTFFQRAGYVELRPENAALEPIIVKECRILGVVCGLYRLY
>NZ_LT632322.1|WP_071705445.1|944243_945914_+|nucleoside-kinase
MCTMRLYTRREGEEVAVSKETTFAECAQKMEEQAQGRIVLARVKNHLFELAQPIPEEAEEVVLMDTTDSDGYRVYMRTLSFVFLEAIERLFPDTHTVIEHSISGGLYCVLHRKGHVFMLDTRQRDELKAEMRKIIEADMPIVRENMTYEEAKQLFRTLGRADKVELYAQQTGNHVAVYRMGNAVDSFFGYMAPSSGYVTVFDLELFDHGLVLLGVDRQDKTRVNNFVPTYLLSDTYNEAEDWADRQGIYTVAQLNRSIQNGTIGDVCRMNEALQDHKIMHIAENIVLKNKRIVLIAAPSSSGKTSFAYKLMTSLRVLGKRPVAISLDDYFVDRENTPLDEQGEPDFEALEAIDLRTFNADMRALLTGEEIERIRFDFVAGKRVHTEERIRLGAEEPILLEGIHALNPKLSSDVDNRYKYRIALSVITQINLDAHNRIPTTDLRLMRRMARDLQFRGRDVRQTIRTWPDVRRGENRNIFPYSELADVMFSSSFVYEIAALKPILEPHLREIGEDEPERIEAVRILSLLQYFLALTDTSDVVNTSILREFIGGSKLVH
>NZ_LT632322.1|WP_071706101.1|946052_946907_+|pyridoxamine-kinase
MKQQPQKSAPTPRILTMQDISCVGQCSLTVALPILSACGMETCVLPSAVLSTHTGFSTFTFRDLTEDIPSIMENWKQQGLLFDALYTGYLGNVQQIELVKELAQNVLVPGAKTYIDPAMADHGKLYVGFDSAFVDAMKTLLPIADVLLPNITEACLLTDTPYREEGDAAWMHTLAEKLLAFGTKNVVLTGVSTKPDTTGVLVMGEAGEEWYTHALLTPGSHGTGDIFASVFVGAHVRGKSLGEAARLAADFTCLALEETHKDPDHWYGARFEPVLGRLVKMLEA
>NZ_LT632322.1|WP_097677421.1|946913_947789_-|polyphosphate-kinase-2-family-protein
MSEQKTLDTKRYLVDGDTFSLAKHDPGDRQGWKKKEGQAALHANQEEMFILQQKLYAENKQALILVFQAMDAAGKDGCIKHVMRGLNPQGTHVVSFKQPSSEELDRDYLWRINRALPRRGEIGIFNRSHYEEVVVTQLHNLVENQQLPDFVLEKPIWKERYRQIGDWERYLYEQGYHIVKFFLHISEEEQRQRLLARIEEKDKNWKFSAGDIAEREHWDEYQKLYEKALQKTSTKACPWYVIPADHKWFSRLLVSQIVRETLEQMDPQYPRLSPEEESRLGEWREVLESQA
>NZ_LT632322.1|WP_071705446.1|947831_949316_-|carbon-starvation-protein-A
MITFLCGLLILVLGGAVYALFIERLFSPDDRLTPAIARADGIDFTGMPTWKNALIELLSITGTGVILGSIQAVLFGPIAFLLIPLANIFGGAVHNYLTGMIAMRNRGMQMPGLVEKYLGLGVSRIFLFLLMALLFSTGVVLLYTTGDYIGQSFPTSLSREAGLYLLLYVGLLVYFIVTTLFPIDRTIGRIYPLFSMVLFVTTLALFLGILRDGLGSLPEITKVTAIPSLGQGRVLPVFFITLAHAILSGLHASQSTLVARTVCKESDGRAVFFYTMLAEGFLSMCWAGGAMILLARHPNLVNTLEPVALVGAVSREFLGGWGDFFALLCLFVLPITTGDTVFRAIRLIFGELFHVNQRLPWKRFVTTVCVFLPALFLLVLAKTNIYGFSRLWRYYGFLSQVVATFGLAMASVYLHAHYKNYWVAFLPMLATCFIATSYILHAQGGLQLDALLGNPESYRASYTLAFLFTLLIGMLVRRHAVEHSHAIRIREEER
>NZ_LT632322.1|WP_071705447.1|949312_949684_-|chorismate-mutase
MATSKKSTKSSEQKSNAALASSSSDTLESLRRQIDAIDRQMARLFEERMRLSRTIGAWKKATGKPVRDEKREAEMLASHRQWIKDVSLRESYGTFLQGILQLSRDTQHHDLLEQRDHEEGDCP
>NZ_LT632322.1|WP_071705448.1|949783_951322_+|hypothetical-protein
MQNTSLRRKFWIGCSLALMLLFHFLPPFSGMSESAMTVLGLFIGVLLLWLFVAIDWPSLVLLAGLMTVPEWKTADVFAASFGSPTVLCLLFTFVLTHALAETGVLRRIAVAFITCRPARRGPWHFVALYFAGILFLGSFISPTVLFFLYLPMLEEMYAVLGLKKGDPAAALLMMGTVIMTGISSGMTPIAHVFPLIAMNAYEVYAGVPVSVGRYLLLAVPVGLVTAAGMLLLFRLLLHPDPNAFHPDRAERLKERLFQEKNAEEVSTVDSLDERALTSQYTDGQMHRARKVVGVFLFVLFLWIAPDLLVRLIPLQGVQQLFSTLHRLGPAFPPLIGCVMLALFSDDGKPLLYLDKAFREGIAWPAILMCAGTGALGWALTQPTIGWSDWLAAHLSSLASSFSPALLFFFFALWASLQTNLSSNMVTATVVSAAAIGALPQLLGISGELLLSMIGMLSAYAFATPPAMPCVAIAGSSGWTTTRQMMRYGFLAMLIGVVVASAWACCLNALFLG
>NZ_LT632322.1|WP_071705449.1|951744_952749_+|methionine-ABC-transporter-ATP-binding-protein
MIRVEHVSKEFSADNGVLHAVRDVSFEVGEGEIFGIIGLSGAGKSTLVRLLNRLEEPTSGHIAIDDVEVTKLNAQELLQARKEIGMIFQSFNLFRQKSIRKNIAYPMQIAGWSKEKTKARTDELLQFIGLADRANAYPSELSGGQQQRVAIARAMALQPKILLSDEGTSALDPKNTASILELLRDLAQTYKTTIVMITHQMEVAKEICDRIAVMADGEIVEMGTTRDLFFQPKHSVTKSFISKLQDADEFGFLRNREFAGDVVKLTYRKETIQHSLIADVLKQFPVGISILSANIDTFRQGEIGYTIIELTGQEADRMCALDAFRKQVDVEVMK
>NZ_LT632322.1|WP_071705450.1|952745_953390_+|ABC-transporter-permease
MITEILTQATLETFYMVFFGAAFAFIIGTPIGILLYLTQEGGLSEKPVLYRVVDVIVNIARSIPYVILMILLIPVTRAIIGTTIGSTATIFSLAASAAPFFARLVETALNGVEGGIVEAAKAMGSTNRQIIFQVLLPEALPSLIQAMTTTIINLIGYTAMAGALGGGGLGAVAQRYGYYRRQEDLLWASVIVIVLLVQIIQLAGNKLARSIDKR
>NZ_LT632322.1|WP_071705451.1|953475_954345_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKSLLALLFALALIFTACGNSAPKKDDSKEAQSAAPESSVSQEASSGAEQQTIKIGVSPVPHAEIVEAVKDNLAKRGINLEIVTFDDYVIPNQALASGEIDANFFQHLPYLDAFKKENNLKLVSIGAVHLEPLAAYSTKYKSLEELPEGAKVLIPNDVSNGARALLLLAKHNLIKLDDPTNINVTEANITENPKKLTFVPMEAAALARTYQDADLALINSNFALAENLNPIKDNLVIEDKDSPYANIVAVREGEENEEKFKILMEELQSETVKKFINDKYQGAIVPAF
>NZ_LT632322.1|WP_071706103.1|954572_956174_+|VWA-domain-containing-protein
MKKKLVSIISISLALLLLASGCTNKKESRSDDAQKAVTTEKKEDTAKSSSDKGEQETDSAQQGKSEEDYQRKEGVNGPLPAVNYTYDAIVDAAGGICRFPSVYEEHYQENVKTWNQQVKEEVKKIAPKLTEDASDKEIQHLFQQFLYIAGNDYPVFEPIERYSYVVFKKDGEDPFTHKKINENVNVNLEIALDCSGSMANTIDGKTMMEIAKQSIGDVLSKMPEKAKVGLRVFGHKGNNEESGKQESCAACELLHPMETLDKKKLETSLKPINPTGWTCIAKSIEEGVNDLSSFKGEKDLNILFIVTDGIETCGGDPVAMAKKLKGDHTNIVLGIIGFNVDANQNLVLKQIADAAGGYYASANDAASLTGELQTIHELAYSTYKWQELDTALLNTLKGFHTGCLSHNKIHLQNGPIAEKNSLTTLLSYAGAPDVGLFPSGSQVEKKLRTLIEERYQKITALFEEEAAKREKESQDYFAAITPRLGETVAVIPMTSRVNPSSDYWKDYSNKGGNNQSQQEDTNRLEESVHPDSK

Crispr_ID: NZ_LT632322_8

• CRISPR_ID: NZ_LT632322_8
• CRISPR_location: 1281519-1281646
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT632322_8

Consensus_repeat	Method
CGCCCTGCGCGCTTCGCGCTTGGTCTTGCGGGAGCTCTGGCAATC	CRISPRCasFinder

spacers of NZ_LT632322_8

>8.1|1281564|38|NZ_LT632322|CRISPRCasFinder
CCACGGCGCTTTCGCCTCTGGATGCCTCGCTCACCGCT

CRISPR arrays and Neighbor proteins around NZ_LT632322_8

CRISPR arrays

The CRISPR arrays of NZ_LT632322_8

>merge|NZ_LT632322|8|1281519-1281646|CRISPRCasFinder
CGCCCTGCGCGCTTCGCGCTTGGTCTTGCGGGAGCTCTGGCAATCCCACGGCGCTTTCGCCTCTGGATGCCTCGCTCACCGCTCGCCCTGCGCGCTTCGCGCTTGGTCTTGCGGGAGCTCTGGCAATC

>NZ_LT632322|8|6|1281519-1281646|CRISPRCasFinder
CGCCCTGCGCGCTTCGCGCTTGGTCTTGCGGGAGCTCTGGCAATC	CCACGGCGCTTTCGCCTCTGGATGCCTCGCTCACCGCT
CGCCCTGCGCGCTTCGCGCTTGGTCTTGCGGGAGCTCTGGCAATC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705718.1|1292048_1293833_-|V-type-ATP-synthase-subunit-A	unknown	unknown	gnl|CDD|235248
NZ_LT632322.1|WP_157885041.1|1288445_1289960_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NZ_LT632322.1|WP_071705705.1|1273013_1273265_-|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl|CDD|224109
NZ_LT632322.1|WP_071705708.1|1276042_1276558_-|peptidylprolyl-isomerase	unknown	unknown	gnl|CDD|223725
NZ_LT632322.1|WP_147659385.1|1295168_1297112_-|V-type-ATP-synthase-subunit-I	unknown	unknown	gnl|CDD|235600
NZ_LT632322.1|WP_083428242.1|1273348_1273822_-|dUTP-diphosphatase	unknown	unknown	gnl|CDD|234802
NZ_LT632322.1|WP_071705707.1|1274876_1275746_+|neutral-zinc-metallopeptidase	unknown	unknown	gnl|CDD|282131
NZ_LT632322.1|WP_071705717.1|1290684_1292052_-|V-type-ATP-synthase-subunit-B	unknown	unknown	gnl|CDD|235251
NZ_LT632322.1|WP_071705710.1|1277052_1278729_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705714.1|1287346_1288351_-|asparaginase	unknown	unknown	gnl|CDD|199207
NZ_LT632322.1|WP_071705704.1|1272333_1273017_-|septum-formation-initiator-family-protein	unknown	unknown	gnl|CDD|368217
NZ_LT632322.1|WP_071705703.1|1270841_1272323_-|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl|CDD|238950
NZ_LT632322.1|WP_097677423.1|1294709_1295135_-|ATPase	unknown	unknown	gnl|CDD|349413
NZ_LT632322.1|WP_071705706.1|1273899_1274697_-|HAD-family-phosphatase	unknown	unknown	gnl|CDD|319818
NZ_LT632322.1|WP_071705716.1|1290048_1290681_-|V-type-ATP-synthase-subunit-D	unknown	unknown	gnl|CDD|224312
NZ_LT632322.1|WP_071705720.1|1294448_1294700_-|V-type-ATP-synthase-subunit-F	unknown	unknown	gnl|CDD|376707
NZ_LT632322.1|WP_071705719.1|1293825_1294446_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705723.1|1297122_1298148_-|V-type-ATPase-subunit	unknown	unknown	gnl|CDD|376708
NZ_LT632322.1|WP_071705712.1|1280508_1281048_+|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|224508
NZ_LT632322.1|WP_071705711.1|1279073_1280342_-|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl|CDD|226206

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705718.1|1292048_1293833_-|V-type-ATP-synthase-subunit-A	gnl|CDD|235248	PRK04192, PRK04192, V-type ATP synthase subunit A; Provisional.	0
NZ_LT632322.1|WP_157885041.1|1288445_1289960_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	9.00007e-60
NZ_LT632322.1|WP_071705705.1|1273013_1273265_-|RNA-binding-S4-domain-containing-protein	gnl|CDD|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	7.0776e-25
NZ_LT632322.1|WP_071705708.1|1276042_1276558_-|peptidylprolyl-isomerase	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	4.41926e-71
NZ_LT632322.1|WP_083428242.1|1273348_1273822_-|dUTP-diphosphatase	gnl|CDD|234802	PRK00601, dut, dUTP diphosphatase.	8.61078e-45
NZ_LT632322.1|WP_071705707.1|1274876_1275746_+|neutral-zinc-metallopeptidase	gnl|CDD|282131	pfam04228, Zn_peptidase, Putative neutral zinc metallopeptidase. Members of this family have a predicted zinc binding motif characteristic of neutral zinc metallopeptidases (Prosite:PDOC00129).	1.04962e-99
NZ_LT632322.1|WP_071705717.1|1290684_1292052_-|V-type-ATP-synthase-subunit-B	gnl|CDD|235251	PRK04196, PRK04196, V-type ATP synthase subunit B; Provisional.	0
NZ_LT632322.1|WP_071705714.1|1287346_1288351_-|asparaginase	gnl|CDD|199207	cd08963, L-asparaginase_I, Type I (cytosolic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type I L-asparaginases, which are highly specific for asparagine and localized in the cytosol. Type I L-asparaginase acts as a dimer. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase. One example of an enzyme with no L-glutaminase activity is the type I L-asparaginase from Wolinella succinogenes.	3.91657e-145
NZ_LT632322.1|WP_071705704.1|1272333_1273017_-|septum-formation-initiator-family-protein	gnl|CDD|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	3.59868e-05
NZ_LT632322.1|WP_071705703.1|1270841_1272323_-|tRNA-lysidine(34)-synthetase-TilS	gnl|CDD|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	1.37965e-55
NZ_LT632322.1|WP_097677423.1|1294709_1295135_-|ATPase	gnl|CDD|349413	cd18120, ATP-synt_Vo_Ao_c, Membrane-bound Vo/Ao complexes of V/A-type ATP synthases, subunit c. Vo/Ao-ATP synthase subunit c. The V- and A-type family of ATPases are composed of two linked multi-subunit complexes: the V1 and A1 complexes contain three copies each of the alpha and beta subunits that form the soluble catalytic core, which is involved in ATP synthesis/hydrolysis, and the Vo or Ao complex that forms the membrane-embedded proton pore. The A-ATP synthase (AoA1-ATPases) is exclusively found in archaea and functions like the F-ATP synthase. Structurally, however, the A-ATP synthase is more closely related to the V-ATP synthase (vacuolar VoV1-ATPase), which is a proton-translocating ATPase responsible for acidification of eukaryotic intracellular compartments and for ATP synthesis in archaea and some eubacteria. The V- and A-type synthases can function in both ATP synthesis and hydrolysis modes. The V1 complex consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The Vo complex consists of five different subunits: a, c, c', c'', and d. The Ao/A1 complexes are composed of nine subunits in a stoichiometry of A(3):B(3):C:D:E:F:H(2):a:c(x). ATP is synthesized on the A3:B3 hexamer and the energy released during that process is transferred to the Ao complex, which consists of the C-terminal segment of subunit a and subunit c.	1.2099e-15
NZ_LT632322.1|WP_071705706.1|1273899_1274697_-|HAD-family-phosphatase	gnl|CDD|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.33425e-56
NZ_LT632322.1|WP_071705716.1|1290048_1290681_-|V-type-ATP-synthase-subunit-D	gnl|CDD|224312	COG1394, NtpD, Archaeal/vacuolar-type H+-ATPase subunit D [Energy production and conversion].	6.15797e-29
NZ_LT632322.1|WP_071705720.1|1294448_1294700_-|V-type-ATP-synthase-subunit-F	gnl|CDD|376707	pfam01990, ATP-synt_F, ATP synthase (F/14-kDa) subunit. This family includes 14-kDa subunit from vATPases, which is in the peripheral catalytic part of the complex. The family also includes archaebacterial ATP synthase subunit F.	6.63586e-09
NZ_LT632322.1|WP_147659385.1|1295168_1297112_-|V-type-ATP-synthase-subunit-I	gnl|CDD|235600	PRK05771, PRK05771, V-type ATP synthase subunit I; Validated.	2.31787e-89
NZ_LT632322.1|WP_071705723.1|1297122_1298148_-|V-type-ATPase-subunit	gnl|CDD|376708	pfam01992, vATP-synt_AC39, ATP synthase (C/AC39) subunit. This family includes the AC39 subunit from vacuolar ATP synthase, and the C subunit from archaebacterial ATP synthase. The family also includes subunit C from the Sodium transporting ATP synthase from Enterococcus hirae.	1.10048e-20
NZ_LT632322.1|WP_071705712.1|1280508_1281048_+|rubrerythrin-family-protein	gnl|CDD|224508	COG1592, COG1592, Rubrerythrin [Energy production and conversion].	5.80983e-57
NZ_LT632322.1|WP_071705711.1|1279073_1280342_-|serine-dehydratase-subunit-alpha-family-protein	gnl|CDD|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	1.09248e-94

Protein sequences

>NZ_LT632322.1|WP_071705712.1|1280508_1281048_+|rubrerythrin-family-protein
MKNKYAGTQTEKNLQTAFAGESQARNKYTFFASKAKKQGFEQIAALFLKTAENEQEHAKLWFKALGGINDTTDNLKDAAAGENYEWTDMYDGFAKTADEEGFPELAEQFRGVAAIEKHHEERYRALLHNIEAQQVFARSEVKIWECRNCGHIVVGEKAPDVCPVCHHPQAFFEIAAQNY
>NZ_LT632322.1|WP_071705711.1|1279073_1280342_-|serine-dehydratase-subunit-alpha-family-protein
MKENKVHPYFAFLSREMLPAFGCTEPIALAYAACEARAILDAEPARILVRCSGNLIKNAKSVLVPNANGRRGIAISAALGAMCLEPERKLQVLEHITPEQRKRAENLVDQGACRVEHDVEREGLYLSLTLWDAAEHSARVVLSGEHTNIVRKERDGAVLYEKAEQDHAASYPPFSFADIYTFAKEADYTPVLPLLDQEIRYNLAIGTEGLTHEWGSSIGKAILREGTTVADEIAYAAAGSDARMSGCKLPVVINSGSGNQGMTVSLPIIRHAEHIHADEDRRYRALLFANLLAAYQKSYIGRLSSYCGAVSAAAASVAGVAFLDGATPAVIAETVVNALAAAAGVLCDGAKPSCAAKIALALRASYTAYEQAKEGRSFKTGDGMVAVDVDATIRSIGRVAREGMAETDRVILQEMLATTNKG
>NZ_LT632322.1|WP_071705710.1|1277052_1278729_-|hypothetical-protein
MNKKNRWGRVLLSLLLIVSMVAGMLPCNAVAETVDDPSGIQYDAEGNLIIKNQQALQDKIKEATALGVTVNVTPQAKDPVYVRDAKALENAKTEIEKNNADSIEALDGAITAQKNNNAEYQTKLKESFKDIQGTEWSFEDIQKFILTKDEQKLTEDMQLAKMVQRMSAASVVTPSSQSTLITPLNLKNPGYLTEGDTLRYANVLQDSATGEWVDFKLTIKRIDLVHTPPYKKGEAKKTELKPNKNHSAYDIDPKKPLIYYSCDDLTIQVDFLKHGTEEPISIIPILVFVDVDVTQAVKLESPASHNALKGKKLGYDATNDKFFDAKGDDDGNPDGDDRDNWVMYSTGATTGFTYTFYTQRENFTGVIQGIGGDSVKYTPPAKPKSETANVTLIKQPIYHQVSYQFVGNYPKKAKIPTDATKYAVGQQLNMAADPDKISGWTFLGWFEDQTLKTPIQAHPVNADEIIYGAWKKKPTPPTISSSVSSSLPLSSDSMSTVPGIPQTPEQPPETPNTPKPKKPNAKAPRTGELENRMWGITLLGLTAAAVGFATIKKKKSMR
>NZ_LT632322.1|WP_071705708.1|1276042_1276558_-|peptidylprolyl-isomerase
MKNPIVTFRLPQGEIQAELYPEIAPNTVNNFISLVQKGFYDGLIFHRVIPQFMIQGGDPEGTGMGGPGYTIAGEFAHNGFANALKHEAGVLSMARSMDPDSAGSQFFIMHKDAPHLDGEYAAFGKVIEGMDVVDAIAHVKTGWGDRPKDDVVMTKVTVETFGESYPEPDKL
>NZ_LT632322.1|WP_071705707.1|1274876_1275746_+|neutral-zinc-metallopeptidase
MRWRDRQGSSNVRSGGRGTGKIIGGGSLLLGLIVLLLTGNPLAALNVGLNSAPITNGSVRQEPLSLSEKEKELYHFSSVALKDTEDTWHTLLKQQKKDYQEAEMIIFQQKVKTGCGIADSGTGPFYCGRDRSVYMDLSFYDMLVNQFGAEKNEFILSYVISHEIGHHVQNELGILDEVNRLRQRAGEAERNALTVRLELMADYLAGVVARHQQEEGYLEKGDLDAAIQSAWSIGDDAIQKRIQGHVTPESFTHGSSKQRARWYKKGYEAGNLDDFNTFDLDRYPTVDSL
>NZ_LT632322.1|WP_071705706.1|1273899_1274697_-|HAD-family-phosphatase
MIRLFCSDFDGTLSPNTTISPENIRAIRRLQDAGIVFALVSGRPKANAHMLLARAGLTVPMITSNGSVVTLADGRDLLVKGIATDAIEDILEVANKRKSFYIAYEKDRCFLPPWVPFLGVGGLARLVQRETGILPLRVKREDLSGWTVTKFNYYPLGKPTEADWHRWEQDERVYVTTSSRHKLELSAAGVSKGNAIRLLAKELGIRSDEIAAIGDYLNDCDMLKAASLRFAVANAREELKAIADHVVSSAKENGVAEAISQVLAD
>NZ_LT632322.1|WP_083428242.1|1273348_1273822_-|dUTP-diphosphatase
MNEEKKASTTARENGPIVMRYCATGKKPSYSNAFAAGLDLPLMNEEGLTFHPGDHGVVHTGISVELPKGTFGLVAIRSGLGMKGLVLSNGIGVIDEDYRGEIRIPLFYHGEDTLHLAQGERVAQMIVVPYLQPILEQTETLSETDRGEEGFGSSGRF
>NZ_LT632322.1|WP_071705705.1|1273013_1273265_-|RNA-binding-S4-domain-containing-protein
MRVDKFLKNARLIKRRTVAKQAADGGRIDVNGRTAKAGTEVAAGDTMKIAFGNKTLEIEILAVPETVRKEQAQEMYRVIGEEE
>NZ_LT632322.1|WP_071705704.1|1272333_1273017_-|septum-formation-initiator-family-protein
MSQFKSILPKTDPSGAPRQKRSSDEEEILQRGGRVDARRASRKKEGRSVRKASRLNNAAEQGRSYRKRSPFNRSSLGVVALFVILLLILIPTALTLNSTSKQLTETKAMQSSLEAQREELQTSVNDLKSQLDIVNTDQFIEKYAHEKLGMLRPNEILVDMGDGTMQINQDALAKYKAEQEQKAAQASSTAPAAESASTQPTASGDTNASTAPLAEQSPESSASNNGQ
>NZ_LT632322.1|WP_071705703.1|1270841_1272323_-|tRNA-lysidine(34)-synthetase-TilS
MPTFSSEVVSLLETPRRIYVAVSGGADSMAVARLLKDALQGRPSLSTPTVLHVHHGLRGEDADADERFVADWAETHGWRFCSTHVDVAERVRQTGESIETAARVLRYAFFTRVIDEEWTSDEPKPLLFLGHHLQDQAETILFHILRGCGPDGLSGMAELEERSSFFLVRPLLSATKESIEQFHRARCFTWREDHTNQEMDATRNRLRNLFFPALRRDINPAVDESLVRLGEIARADNAYLDAVAQASFSRMSETGAQADPFSSSSLARNAYFLKSIALRRDAFLAEPLAVQRRIIRHWVRAFWLREKQEAAMLPFEEEEEIRRHFRRPSGKCLSLYGMMFLTDFEGVHVLSLARFQTLERESEACLTLSADRDGRQQDIFSGRCTVSCISQVDSATVSSLTSLPAASCAIDATELDGLTWHFARAGDTFVSFGGGSKPLRKMWNAWHVPAVLRNHWPILTDGEDILWVLGLGRSARRIVQPGRNMVIINWRKI
>NZ_LT632322.1|WP_071705714.1|1287346_1288351_-|asparaginase
MNKKILLLGTGGTIASVATKDGLTPAITAEELLAYLPELSPSIEVDAVQLLNLDSTNIEVCHWLAMAKAIEEHYDAYDGFVLCHGTDTLAYSSAALSYLIQHSPKPIVLTGSQKPINLDNTDARVNLRDAVRFAADSRAHDVNVVFEGKVICGTRVQKVRTKSYNAFDSVNYPLLAAIQEKRIAFYIDDKVSQSAPAHFSSVLDPAVGLFKLTPSLDPKMLTIFGRSFHAVIIEAFGVGGLPTYRAGDYRDAVESLLREGKTIVMTTQVPYEGSDMSVYAVGRDVKEDLDLWEAYDMSLPSVVTKLMWVLGQTADPKEARKLFQTPINRDTLWF
>NZ_LT632322.1|WP_157885041.1|1288445_1289960_-|ATP-binding-cassette-domain-containing-protein
MRKNKAYWLTLLFTMLNVAANVLYNFAMALLLEALIAQDFHRLIWAVGVNFFGVFIILATDAAMKIFQAQYIIDQQLQMRKIQISRLSGYEISNLTSDMDLLENNFFTPYFNSIENGLQIAMALAALLWIDWRLACVSLVLFGVIVITNSKMGPYSERMVQEYSAANETFLHHLTDLFNGRKVYAVFDFSRGFKEAHMPLFRAFNEAWISLKHRSIVLEQISALSSVIAQVVNLFVLALLIFIGAIPISLVLTAGNLTGQLYNSLASFPELLSKVKGARPLYARLSKGEAEDDKEKPILEHELTASGLTKRYGEKTLFQAVNVSIRRGENVRIAGPSGSGKTTLLNILFGIDSPDDGTIQIDGTVISPYHGVRNMAYITQNNYIFENTVRFNITLGDTFSNEEIARVAHLVGIDRFVNQDGLDMNLLEHGENISGGERQRIALARALIRKKDVILVDETTSNLDTDSAREIEEILLQDPDITFVYVKHDEHAEEDPRFDRIITL
>NZ_LT632322.1|WP_071705716.1|1290048_1290681_-|V-type-ATP-synthase-subunit-D
MAFFKITPTKANLMKVKAMLALMESSYTLLDKKRVVLLRAANAEQKKKADLEARLQTVSADFKEKLKHATVAMGHYRLESIAAGMPFDESITLSSRSYMGVEVPHLHYEESTKDELDYDTVHITLDFATGAMQEFKSILLELASVTDAADRLQREMLKTQKRANALEKVQIPKYKKYRDFIAQSLEEKEREEFFRLKLLKKKKMRKKQKA
>NZ_LT632322.1|WP_071705717.1|1290684_1292052_-|V-type-ATP-synthase-subunit-B
MNIEYIKLKHLESAIVTVDKVNDVGYGEIVTITSEGKTYTGQVMAIEDDLAMVQVFGDTTGMRVDNAVVTFEGHPLSIPLNASILGRVFDGLGNPIDGGGAVFSNKRYNINGSAMNPVAREYPKNFIQTGISAIDGLMTIIRGQKLPIFSGSGLDHDRIAAQIIRQSQIRHSDDDFCFVFGAIGVQKDEADFFEETFRAAGVQDQVASFINLADDPVMERLITPKCALTAAEYLAFEEHKHVLVLLTDITSYAEALREISNLREEVPSRKGFPGYLYSDLAAMYERAGILRSGKGSITLIPILSMPNDDITHPIPDLTGYITEGQIVLSRELSRRGIYPAIDILPSLSRLMKDGIGEGFTREDHADVMRQIYASYAKAQEVRNLAQIIGEDDLSEDDRKVLAFGDAFEKQFLQQEFTENRSIEETLDLGWQLFSLLPDGELSQVSPEMKEKYLKR
>NZ_LT632322.1|WP_071705718.1|1292048_1293833_-|V-type-ATP-synthase-subunit-A
MNKTAEGIIRAINGPVIRGTRMNGFGIHEMVEVGENRRLGEIISLDEDRAVIQVYEQTEGLKVGDAIYATGEPLSVVLGPGLLMNMFDGIERPLERIQDAHGDFMATGVKMPALDDTKKWTVSMKVHEGDTLSSGQIFATCKETVLIEHRAMVPNGMAGKVVSCVADGDYTVHDVLAVIEQDGIRHELTLMQRWPVRRPRPVSRRLSTNDLLVTGQRVLDVFFPIAKGGTVAIPGGFGTGKTMLQHQIAKFCDADVIVYIGCGERGNEMTDVLDSFPQLIDPNTGENLMNRTVLIANTSNMPVAAREASIYTGITMAEYYRDMGYDVALMADSTSRWAEALREISGRLEEMPAEEGYPAYLSSRIAQFYERAGRVENLNASTGSVTLIGAVSPAGGDFSEPVTEATKRYVKVFLGLDKELAYSRHYPAINWMNSYSGYTELLANDYLDRTDVDVMALRKKMMGILLEESKLNDIVSLVGADVLPDEQRLVLEIARVIRVGYLQQNSFHAQDTYVPLKKQVRMLQVINTLYENGRDLLRLHAPLRIVRDDALYQKVTMMKYNVANDNLSAIDDLEEAIVSHYDALKMQYQGEDAS
>NZ_LT632322.1|WP_071705719.1|1293825_1294446_-|hypothetical-protein
MVELQSKLALFRNMIWSEEKRRSEQMLYDSTTQNSKLIEERKARLKRESEQYIEQHVDRAKREAREQLVVHRQENQRVFLETQKKCLDALNASIRQKFADFAQTPEYAAWMKKHLRAALEEMDVAEVHVLDRDQDLAHEICGEDLPIKSMPEEEIGGFVLVDRQQAKRTRHTFQYLIQDNEYEIGRALNDWLMNGAIQEAEGEAHE
>NZ_LT632322.1|WP_071705720.1|1294448_1294700_-|V-type-ATP-synthase-subunit-F
MHMKLITDNRELALGSRLSGIQTREVDEHTDLSEEWNMAVEDTDLGVLYLSKHVAEALQEEIDTFRAKHHRPIVVVLPEQKEN
>NZ_LT632322.1|WP_097677423.1|1294709_1295135_-|ATPase
MAPILTLSTIIVVLTISSGIYLLYKNTDSSKKRLKHALRLNLTCFAPCILMALILFMPSTAFAQGNANNAASGLAYLGAALSTGMATIGTGIAVGACGSAALGAVSEDQSILGKTLIFVGLAEGIAIYGLIISIMILGQIG
>NZ_LT632322.1|WP_147659385.1|1295168_1297112_-|V-type-ATP-synthase-subunit-I
MAIQRMKMMQLVAPLDQLSPIVLALFRTGGLHLLDAEKRIENYSFTIPVTEENLSKTVDVSTVRQFEKESDTGERRQAALTYLQRKPREMGDIFSQPNLTTELTTQQEAVLAGLMKLDADIEEIREKQKQVETDLSLLRLLSANDIAYSALQSLEQFAYEFGTLTAIERRAIRSGYEKIPAAILHLGAIEKEEFYLLVYPNKVQNEIRRLEDRLNWKPLHPDFPQGKTNEECIRFMEEEIQKEERQLQDLEKEKQTRIDRHEKDLEGLYYAASLNDAVNSAKQYFARGKSYFYVTGWVSEKEENAFRRTIAAFKDTFVQFMDEEHVSEKAPTRLKNSAIVRPFEAMVNMYGTPNYKELDPTGFFAITYVILFGAMFGDLGQGAVFALLGLLLKKMRHPNLGGVVFRMGLASMVFGLAYGSFFGLETVIPALVMRPFENINTVLIAAIVFGVILSSVAYILGIVNKWSRKEYQEAWFGKEGLCGFLLYLSLLLTVVNVAVQPVLPSGLLTVLIAASLAGILFQQPLTNVLLRKRPLYRQAVGDYYVETGFSLLEALISVFSGALSFIRVGAFAINHVGLFMAFSTMGRMIGGAGNVAMLIIGNIVIIGLEGLIVFIQSLRLEYYELFGKYYVGDGKPFIDAKKMFLHR
>NZ_LT632322.1|WP_071705723.1|1297122_1298148_-|V-type-ATPase-subunit
MGSDTALVTKLRGRFGKYLDPQQLVRLLEETTLEGAFRVIREIVGEDLGDFQDVRGGEQRLEAWKRRRNDELLTFLDAKQKQFLHSFFIEDELLELQRFLRVLQRDNRKEQLLFIQHSIYADTLHLTADTSIRVPTYLSTLKEKPYYRLLEPIVHNDAATGPIDFDSLMVNFNRWYFHRLRKEAKDIGGKTAAVLNDLLGTMIDLRNITWIVHTKRFLREEDPYLAMQMVSGGKILYGKTLDNAVGMDLPAFTVWLRHSPYRGLVEGGKEDYSFLPIARQRYLYRRCRKIFRLTDDGLLAAVCFIHMLNGRIAEIRRILEAINLGWKEEQMIQYLIEWKTE

Crispr_ID: NZ_LT632322_9

• CRISPR_ID: NZ_LT632322_9
• CRISPR_location: 1389928-1390043
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT632322_9

Consensus_repeat	Method
CCGCCCCTGTTAAACGCCCGACTTCGACC	CRISPRCasFinder

spacers of NZ_LT632322_9

>9.1|1389957|58|NZ_LT632322|CRISPRCasFinder
GTTCGTCAGGGTCCTTTGGTCCCTGACATTTCACGAAATTCACCACTCGTCAGGGACG

CRISPR arrays and Neighbor proteins around NZ_LT632322_9

CRISPR arrays

The CRISPR arrays of NZ_LT632322_9

>merge|NZ_LT632322|9|1389928-1390043|CRISPRCasFinder
CCGCCCCTGTTAAACGCCCGACTTCGACCGTTCGTCAGGGTCCTTTGGTCCCTGACATTTCACGAAATTCACCACTCGTCAGGGACGCCGCCCCTGTTAAACGCCCGACTGCGACC

>NZ_LT632322|9|7|1389928-1390043|CRISPRCasFinder
CCGCCCCTGTTAAACGCCCGACTTCGACC	GTTCGTCAGGGTCCTTTGGTCCCTGACATTTCACGAAATTCACCACTCGTCAGGGACG
CCGCCCCTGTTAAACGCCCGACTGCGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071705797.1|1386324_1388841_-|ferrous-iron-transport-protein-B	unknown	unknown	gnl|CDD|223447
NZ_LT632322.1|WP_071705798.1|1388954_1389182_-|ferrous-iron-transport-protein-A	unknown	unknown	gnl|CDD|224830
NZ_LT632322.1|WP_083428255.1|1397037_1398288_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|369639
NZ_LT632322.1|WP_071705801.1|1393273_1393699_+|flavodoxin	unknown	unknown	gnl|CDD|235508
NZ_LT632322.1|WP_172619980.1|1390817_1392179_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_LT632322.1|WP_071705808.1|1398670_1399558_+|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|378820
NZ_LT632322.1|WP_071705805.1|1395578_1397051_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|380302
NZ_LT632322.1|WP_071705791.1|1378676_1380005_-|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl|CDD|224039
NZ_LT632322.1|WP_071705800.1|1392542_1393187_+|DUF3793-family-protein	unknown	unknown	gnl|CDD|378911
NZ_LT632322.1|WP_071705793.1|1380719_1382021_+|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|380481
NZ_LT632322.1|WP_097677432.1|1386034_1386223_-|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl|CDD|378908
NZ_LT632322.1|WP_071705807.1|1398284_1398653_+|DUF1667-domain-containing-protein	unknown	unknown	gnl|CDD|226380
NZ_LT632322.1|WP_071705789.1|1376794_1378000_-|carboxylate--amine-ligase	unknown	unknown	gnl|CDD|226433
NZ_LT632322.1|WP_071705792.1|1380041_1380386_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT632322.1|WP_071705809.1|1399652_1400528_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl|CDD|179769
NZ_LT632322.1|WP_071705790.1|1377986_1378667_-|aspartate/glutamate-racemase-family-protein	unknown	unknown	gnl|CDD|376478
NZ_LT632322.1|WP_071705802.1|1393836_1394421_-|DJ-1/PfpI-family-protein	unknown	unknown	gnl|CDD|153229
NZ_LT632322.1|WP_071705804.1|1394712_1395558_+|aminotransferase-class-IV	unknown	unknown	gnl|CDD|238799
NZ_LT632322.1|WP_071705794.1|1382105_1383614_+|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224053
NZ_LT632322.1|WP_071705795.1|1383629_1385318_+|galactoside-ABC-transporter-permease	unknown	unknown	gnl|CDD|226667

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071705797.1|1386324_1388841_-|ferrous-iron-transport-protein-B	gnl|CDD|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	2.26499e-133
NZ_LT632322.1|WP_071705798.1|1388954_1389182_-|ferrous-iron-transport-protein-A	gnl|CDD|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	3.44042e-17
NZ_LT632322.1|WP_083428255.1|1397037_1398288_+|FAD-dependent-oxidoreductase	gnl|CDD|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	3.0013e-30
NZ_LT632322.1|WP_071705801.1|1393273_1393699_+|flavodoxin	gnl|CDD|235508	PRK05568, PRK05568, flavodoxin; Provisional.	1.61473e-44
NZ_LT632322.1|WP_172619980.1|1390817_1392179_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.10656e-141
NZ_LT632322.1|WP_071705808.1|1398670_1399558_+|alpha/beta-fold-hydrolase	gnl|CDD|378820	pfam12146, Hydrolase_4, Serine aminopeptidase, S33. This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.	6.44079e-40
NZ_LT632322.1|WP_071705805.1|1395578_1397051_+|FAD-dependent-oxidoreductase	gnl|CDD|380302	NF033460, glycerol3P_ox_II, type 2 glycerol-3-phosphate oxidase. This FAD-dependent enzyme (EC 1.1.3.21), glycerol-3-phosphate oxidase, also called L-alpha-glycerophosphate oxidase, converts sn-glycerol 3-phosphate plus oxygen to glycerone phosphate plus hydrogen peroxide, which contributes to virulence. This form, called type 2, is shorter than type 1 and is found exclusively in Mycoplasmas and other members of the Mollicutes.	1.92515e-113
NZ_LT632322.1|WP_071705791.1|1378676_1380005_-|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl|CDD|224039	COG1114, BrnQ, Branched-chain amino acid permeases [Amino acid transport and metabolism].	2.79211e-88
NZ_LT632322.1|WP_071705800.1|1392542_1393187_+|DUF3793-family-protein	gnl|CDD|378911	pfam12672, DUF3793, Protein of unknown function (DUF3793). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 187 and 211 amino acids in length. There are two conserved sequence motifs: PHE and LGYP.	1.40234e-49
NZ_LT632322.1|WP_071705793.1|1380719_1382021_+|substrate-binding-domain-containing-protein	gnl|CDD|380481	cd01539, PBP1_GGBP, periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. GGBP is a member of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic GGBP is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	4.01943e-38
NZ_LT632322.1|WP_097677432.1|1386034_1386223_-|FeoB-associated-Cys-rich-membrane-protein	gnl|CDD|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00272981
NZ_LT632322.1|WP_071705807.1|1398284_1398653_+|DUF1667-domain-containing-protein	gnl|CDD|226380	COG3862, COG3862, Uncharacterized protein with conserved CXXC pairs [Function unknown].	6.49535e-39
NZ_LT632322.1|WP_071705789.1|1376794_1378000_-|carboxylate--amine-ligase	gnl|CDD|226433	COG3919, COG3919, Predicted ATP-grasp enzyme [General function prediction only].	7.08177e-77
NZ_LT632322.1|WP_071705809.1|1399652_1400528_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl|CDD|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NZ_LT632322.1|WP_071705790.1|1377986_1378667_-|aspartate/glutamate-racemase-family-protein	gnl|CDD|376478	pfam01177, Asp_Glu_race, Asp/Glu/Hydantoin racemase. This family contains aspartate racemase, maleate isomerases EC:5.2.1.1, glutamate racemase, hydantoin racemase and arylmalonate decarboxylase EC:4.1.1.76.	9.54153e-50
NZ_LT632322.1|WP_071705802.1|1393836_1394421_-|DJ-1/PfpI-family-protein	gnl|CDD|153229	cd03135, GATase1_DJ-1, Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1. DJ-1 is involved in multiple physiological processes including cancer, Parkinson's disease and male fertility. It is unclear how DJ-1 functions in these. DJ-1 has been shown to possess chaperone activity. DJ-1 is preferentially expressed in the testis and moderately in other tissues; it is induced together with genes involved in oxidative stress response. The Drosophila homologue (DJ-1A) plays an essential role in oxidative stress response and neuronal maintenance. Inhibition of DJ-1A function through RNAi, results in the cellular accumulation of reactive oxygen species, organismal hypersensitivity to oxidative stress, and dysfunction and degeneration of dopaminergic and photoreceptor neurons. DJ-1 has lacks enzymatic activity and the catalytic triad of typical GATase1 domains, however it does contain the highly conserved cysteine located at the nucelophile elbow region typical of these domains. This cysteine been proposed to be a site of regulation of DJ-1 activity by oxidation. DJ-1 is a dimeric enzyme.	1.48711e-63
NZ_LT632322.1|WP_071705804.1|1394712_1395558_+|aminotransferase-class-IV	gnl|CDD|238799	cd01558, D-AAT_like, D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.	4.33032e-95
NZ_LT632322.1|WP_071705794.1|1382105_1383614_+|sugar-ABC-transporter-ATP-binding-protein	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NZ_LT632322.1|WP_071705795.1|1383629_1385318_+|galactoside-ABC-transporter-permease	gnl|CDD|226667	COG4211, MglC, ABC-type glucose/galactose transport system, permease component [Carbohydrate transport and metabolism].	1.87127e-107

Protein sequences

>NZ_LT632322.1|WP_071705798.1|1388954_1389182_-|ferrous-iron-transport-protein-A
MQTLRDVAVGETVKIVKLHGQGAVKRRMMDVGLTKGASVHVQKVAPLGDPIEITVRNYALSIRKADADMIEVVPE
>NZ_LT632322.1|WP_071705797.1|1386324_1388841_-|ferrous-iron-transport-protein-B
MQLRIALAGNPNSGKTTLFNALTGSNQYVGNWPGVTVEKKEGKLKNHTDVIIADLPGIYSLSPYTLEEVIARRYLFEERPDAILNIVDGTNLERNLYLTTQLLELGIPMVIAVNMQDVMEKSGDHLDMPALSKMLGCPIVSISALKNRGIQEAAEAAIRQAQEKAIPTIGKPFAADVESLLAEIDTMLSDTVPSEKRRFVVTKLLEQDQAMAESLQLSEETQQAISEKVEALEESRDDDAESIMTYERYQYIKSLIHPTYQKKGAGKLSTSDRIDRVVTNRILGLPIFAVIMFFVYWVAMVAVGTPATDWANDGLFGDGYHLFGMGTKEYEEDNDAYQNALLAVQAFAEVDPEEEGFDGQETLNELKTVTGEPTQTVKTVDEETLKETVKTVYYNALPNMTEKEMEEKDIIPITFQDAVTYFTAHGFDAPDPADYGTWVPGVPVLIGDLLEKIHVDGWLKGLILDGIVAGCGAVLGFVPQMLVLFFLLAILEDCGYMARIAFVLDRVFRKFGLSGRSFIPMLIGTGCGVPGIMASRTIENESDRRMAIITTTFIPCSAKLPFIALVAGAIFGGDSWVATSAYFVGMLAVIVSGVMLKKTQGFAGEPAPFVMELPPYHVPTVGNVLRSMWERGYSFIRKAGTVILLSTILVWFTSYFGIVDGSFRMLKEDELSMSILASFGNAIAWIFRPLGWGNWQAAVASVTGLVAKENIVGTMGILYGSSGSVWTEMARVFTTISGYSFLVFNLLCAPCFAAIGAIRREMNNTKWTLFAIGYQCGFAYLIALMIYQFGSFFTGSGSILGLIAALAALAGILYMLFIKKYHAPEAKVSHRHPALEQE
>NZ_LT632322.1|WP_097677432.1|1386034_1386223_-|FeoB-associated-Cys-rich-membrane-protein
MQWLSEHLSTVLVAAGLLAIVILIIKVMIANHRKGKSACGCGCGCSGCSGCSTDSMLEKHHS
>NZ_LT632322.1|WP_071705795.1|1383629_1385318_+|galactoside-ABC-transporter-permease
MSQNNLISPNNGILTPEKEELLLAPIQEHISAIQQKIDVLRQDGTTKINEINNAIKLIRGDKNFSKQEQGEQVARLTRELEKAKTVEAANKAEVDKLVAEGEAYLNKHFDPDYYNLVKSSAVLEQKEAKAQYERQLAEYKTKYEAQLAEINKLSGHEKAQEIKDAKFVYNNHTFDAKVRYDVALQEIKDRRHEAFLQKFQMIDRLRNSRFSIGQSYAQKWESFLYRFNMKQFLLKNGLYLVIILIFIALSIITPRVKHTDLFTFTNIVNILQQASPRIFLGLGVAGLILLTGTDLSIGRMVGMGMVISTVIMHKGPNTGQLFGMAFDLTGIPVPVRIILALLTCIVFCTIFTSIAGFFTARFKIHPFITTMSNMLIIFGLITYSTKGVSFGAIESEIPNMIIPKINGFPTIILWAVAAIILVWFIWNKTTFGKNLYAVGGNPEAAAVSGISVFWVTMCAFMMAGILYGFGSWLECMRMVGSGSAAYGQGWDMDAIAACVVGGVSFTGGIGRISGVVVGVLIFTALTYSLTVLGIDTNLQFVFEGIIIIAAVTLDSLKYVQKK
>NZ_LT632322.1|WP_071705794.1|1382105_1383614_+|sugar-ABC-transporter-ATP-binding-protein
MTEKKDDFVLSIRGMSKSFGRNRVLDHIDLDVKRGSVMGLMGENGAGKSTMMKCLFGTYQKDEGEIFLDGKGIDFSGPKEALENGIAMVHQELNQALERSVVDNLFLGRYPVTPLGFVDEALMRKEAADLFRSLGISVPLDVPMRQLSVSKRQMCEIAKAISYHSKLIVLDEPTSSLTEPEVRKLFAMMRKLRDQGISLIYISHKMDEVFEICDQVSVLRDGKLIATKNTAETNMNELISAMVGRSLDNRFPPVDNEPGEPILSVQHLSTKYRPYLTDISFEVREGEIFGLYGLVGAGRSELLETIFGVRTRAAGSVYYRGKRMNFENTKEAMAHGFAMITEERKLNGIFSKGDLIFNTTIANMNHYKSGFALSKQKMLKATMRELDIMRTKAMGPEDMITSLSGGNQQKVIFGKWLERQPHVFLMDEPTRGIDVGAKYEIYELIIRMAKQGKTIIVVSSEMPEILGITNRIGVMSNGRLSGILETKDANQEELLRLSTKYL
>NZ_LT632322.1|WP_071705793.1|1380719_1382021_+|substrate-binding-domain-containing-protein
MKSMKLLGLLLAGALAMTACGGQKPADSKAPADSSAPAVESNAPAGEVKNNEKPLVWYNRQPSNSSTGELDKEALNFNDKTYYVGFDANQGAELQGQMIVDYIQKNADKLDRNGDGTIGYVLAIGDVGHNDSIARTRGVRKALGTAVEKDGAIDSTPAGTNVDGKATVVKDGEIDVNGKKYVVRELASQEMKNSAGATWDAATAGNGIATWSASFGDQIDIVASNNDGMGMAMFNGWAKENKVPTFGYDANSDAVAAIADGYAGTISQHADVQAYLTLRVLRNLLDGVDVNTGIATPDEAGNVLTDKDYKYVAEERSYYALNLAVTADNYKDFMDATKPYDPVAKQLDAAKSPEKNVWLNIYNSADNFLSATYQPLLQKYDKLLNLKVEYIGGDGQTESNITNRLGNPSQYDAFAINMVKTDNASSYTTLLNQ
>NZ_LT632322.1|WP_071705792.1|1380041_1380386_-|hypothetical-protein
MDSERDSQTEQWRYDSSAQAGKDAGIFSFAYWQRLYADNSDGLIGCGAALGAMLFRHSGLLSFLLWIAGLIFSIRGLKKRPQWPAVVGICLSLIGIVILIAVIGLFALFFSLLF
>NZ_LT632322.1|WP_071705791.1|1378676_1380005_-|branched-chain-amino-acid-transport-system-II-carrier-protein
MDQSSTSKRKWIAVASFALFSMFFGAGNVIFPTSLGRNVGNQYLTGFLAFSIPAVGLVLLGAIATIRAGGTIESVARHLGGPISMAFGGLILICIGPGLAIPRTAATSHEMLSGAFFPSLSPTITSLFFFAVTLFFVIKPSRVVSGLGLILTPVLVGILVLLIGKSLVFPLGPLVDTGATEVFSKSFLEGYQTMDALAALAFSIVIIKDFQRRGMEDPSQVVRCTAISSIFAALGLVAVYGGFMYIGATTSGLGVEDIGRVSLLLFSVDKLSGFTGKLLMTIAMFLACLTTAIGLTTTFSDFMERMTKGKISARVWSILCVCVSAVLSVLGVDQIVAISAPILVAIYPIAIALIVLNLVQGPLNRRSIHIGAVIGASFPAVDFLIGLMRGTPILGGKAGLIPEMWQNYYWILPSVILALVFYLVLPKEKEEKPVLHEQMKQE
>NZ_LT632322.1|WP_071705790.1|1377986_1378667_-|aspartate/glutamate-racemase-family-protein
MTYELGVIGGMGPLATNVFYQYLIDHTEAHGDQDHINTIILSHATMPDRSACILSGDTAPLLRQMKADFDLLRPLGLKAIAIPCNTSHYFYDTFCTYTDTPIINMVEESIKECVRRGDKKVVVLATSGTRKSRVYEHYAAKHGLSCLAIDEADAERVMEIIYAVKKENRRDFPELLRMIDQYSNKGRVILACTELSAIPVGDRPVIDALKVLGNEAIRKCRGNGPV
>NZ_LT632322.1|WP_071705789.1|1376794_1378000_-|carboxylate--amine-ligase
MVQFKPIILGTDINAYGTARSFYEAYGVKSLCLGIRPLMYTQHSHILEVETREDFEQDEVFLAVLEEVGRRYTCPLLLISCGDGYTALITRHRDALSVRYRFNYIDQAMQQQLENKKDFYAVCEEYGLDYPDTFVLTYDKRDSFKAPFGFPMALKPNDSIAYLHAKFPGKKKAYRIADEAELRSVVQAIYSSSYKGDLILQDFIPGDFSRMFVLNAYVNTKGEVKMMCLGKCLLDACLPGEIGNYNALVSLGNDAIYAQYERFLKQIGYRGFANFDLKYDVRDGKYKVFEINIRQGRSSSYMTAGGCNFTTFLVDDLLLHVDKPAHYHQDSALWLYVDPQVLRTYCAKEDRDLVERYLAKGFFFPSWYEKDRSLGRFLLYWRRRLSTRRYYPKFQPQRTEQ
>NZ_LT632322.1|WP_172619980.1|1390817_1392179_-|NCS2-family-permease
MIEQLFKLKENGTTLHTELLAGITTFMTMVYILALNPTILSAAGMDPGAILTATAVASAIACFCMAAFSNKPFALSAGLGLNAYFAYSVCGAMGYSWQVALTAVFTEGVIFILLSLTNVREAIFNAIPAQLKIGVAVGIGFFITFIGVQNCGLIVEGPTLVSLYSFTKGAETNASQGVAIILCLVGVLLTGWMLIKGVKGYMLWGMLATWGLGIIAQLLGIYVPAPDAGYYSLIPSAVVSMPKSLAPTLMKLDFSFISHNFLNFVVVCFAFLFVDIFDTLGTVIGCASKANMLDKDGKLPGIKGVLLADAIGTTVGAMLGTSTITTFVESSSGIAEGGRTGLTSVVTGALFLVALFLTPLFLTIPAFATAPALIIVGFLMMQQVSHIAWNDMTKAIPCFACITMMGFAYSISDGIAFGFITYTILHVLTGKAKELSWLMYVLSILFVLKYFII
>NZ_LT632322.1|WP_071705800.1|1392542_1393187_+|DUF3793-family-protein
MNPLYPFQQAIVRHGAETLAGLKPASLLCWETDNVAMDEILAYGRHEFARFDIHFTLLGKCGSAYRILIYRSRLLTEWFLRPDVSYALHSLGYRYDTTSDGRIGAERMFSSCRTRGADLVTRLLDQLQERIRLSPSFPDEIGLFLGYPVEDVLRFMEDHGQNAYPLRGSWRVYHRPKQAEATFNAFRACRQCWLKAMQEGCSLPQLIDRVSVAV
>NZ_LT632322.1|WP_071705801.1|1393273_1393699_+|flavodoxin
MQVGIIYWSGTGNTEAMAHVLEEALKKENVDVEVKNVSEVSVADALGYDRLALGCPAMGDEQLEEVEFEPFYEDLKAEIGKKPVVLFGSYSWNDGQWMEDWTDDARSAGLCLMDDGVACYEGPDDEEKKAALEDLAKALLK
>NZ_LT632322.1|WP_071705802.1|1393836_1394421_-|DJ-1/PfpI-family-protein
MKKILVLLAEGFEEIEALTPVDYLRRADVEVDMASLTEDLSVTGAHGIVVSADTTLDAVDPAVYDGVYLPGGMPGSLNLRDDARVLKIVRDFAGSGKAVAAICAAPIVLEKAGVIANKRVTGYPGTVDKLENVGTYDADAIVVQDENIFTGRGAAAAVYLSFALITALCGEETTKRVKEGIQQQAVEALYGFSS
>NZ_LT632322.1|WP_071705804.1|1394712_1395558_+|aminotransferase-class-IV
MKNLGYYNGQVDLIENIFIPMNDRVCWFGDGVYDAGPCRKQRIFALTEHVDRFYRNAKALQIEMPMEKEAFTSLLCDLVKKLDDEDLFVYYQVTRGTAERNHTYTPGKGNLWVMIKPQKVNDGTKPVSLITCEDTRFFHCNIKTLNLIPSVMAAQKAKEAGCQEAVFYRPGGRVTECSHSNVHILRDGVLYTAPTDCLILPGIARHHLLLACDRLGIPYREEAFSLDELASADEILVTSSSNLCLRADHFDGKAVGGKDFTHYEQLREAVINEFLEETERP
>NZ_LT632322.1|WP_071705805.1|1395578_1397051_+|FAD-dependent-oxidoreductase
MFDVLIIGGGIVGCSIARQLSRYAIRVGLLEKNTEVGQETTKANSAIVHGGFDCVPGTKKAAMNVRGNHLMAKLSEELGFTYHQVGSLVLAFDDEDIDQLHVLLERGRANGVAPLSLLDPPEIFAVEPRVSKRVKKALYCPTSGVVDPFNFTYGMIENAIENGLSLFTETEVTGMERRDDHLVLHTERGDMETRFVVNAAGLGSARIAAMTGDTEIRLRPTKGVYRLLDKTNNECIHTVLFQTPTAKGKGVLVAPTYDGSTLVGPTADAVYDEHDTSVNDEDLRHVDALARKSVSDLALGQTIRVFTGVRAKPESGDFHLYASKHMPGVIHAAGIESPGLVSAPAIAEEVDRLLHENGLSAAEKPNFQPHRKAFVRMAHLSAEEKAEQIAKNPLYGNIICRCETVSEGEIVEAIHRPGGARTLDGVKRRVRAGMGRCQGGFCAPRVIAILARELGVDPITLQKESRGSNLLVGHLKDGHATEQDGSHEKD
>NZ_LT632322.1|WP_083428255.1|1397037_1398288_+|FAD-dependent-oxidoreductase
MKKIDLVIIGGGPAGLAAAIEAKKNGVDSLLIIERDRELGGILNQCIHSGFGVQEFKEELTGPEYAKRFVDQVVAMGIPYVLQTMVVEMTPDKQIVAMNASGIMTIQAKAIVLAMGCRERSAGSVALGGYRPAGVYTAGTAQRLMNMEGLMVGKEVVIYGSGDIGLIMARRLTLEGAHVPCVVEIAPESSGLPRNIAQCLNDYDIPLYLHHKIKAVHGKERVQGVTICGVDDKWQEIPGTERDIPCDTLLLSIGLIPENELSRQAQITLHPRTKGPEVSSHMETTVPGIFACGNVLHVHDIVDYVTQESRNAGRNAAEYILHGAFPPATLATSAGEGISYLLPSRVDPETKESVRLFFRPTRRMRNVLLSLYSGDVLLATYKRNVLIPSEMAHVDVPYERCAQAVSPLRLVAKEES
>NZ_LT632322.1|WP_071705807.1|1398284_1398653_+|DUF1667-domain-containing-protein
MTKKEMVCIVCPMGCALTVQQEKGELRVTGNRCPRGEQYAKQELTAPLRNIASTVRVHNGVLPVVPVKTDREIPKEKIFDTMALINAVAVVAPVRCGECIIPHLFGTDANIVATRDLARHDC
>NZ_LT632322.1|WP_071705808.1|1398670_1399558_+|alpha/beta-fold-hydrolase
MQPKQYSVESACHQPLDVLYYVHEVDAVGNVPRALVQLLHGMQEHKERYHDFAEFLFDQGYDVLIHDHLGHGKSISRLHPLGDMVSADTVLKDIDLVRQSVPVHEQTIFFGHSMGSFLARIYASLYDVDVLIACGTGQTPSFLAHFLKLLLLTQPSGKPLHKLQKLVTGSFSKRGESPTAWLSVDEENQRRYREDPLCGQPFTKEGYETLMDIVLRLNHDETYRNCSADRILLIAGEKDPVGQYTKGVRQAEDRYRAVGKKVQSIFYPNMAHEILQEKDRQIVYQDVLKFLREGQ
>NZ_LT632322.1|WP_071705809.1|1399652_1400528_+|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MEKTQVELNRGLAQMLKGGVIMDVTTPEQAKIAEEAGACAVMALERIPADIRAAGGVSRMSDPKMIRGIQQAVSIPVMAKCRIGHFVEAQLLQAIDIDFIDESEVLSPADDVYHIDKTAFKAPFVCGARDLGEALRRISEGASMIRTKGEPGTGDVVQAVRHLRKVNAQIRQLSAMREDELFEAAKAMQVPYDLVRYVHDHSKLPVVNFAAGGVATPADAALMMQLGAEGVFVGSGIFKSGNPAKRASAIVQAVTNFTDAKLIAEISEDLGEAMVGINAGEIAIIMEERGQ

Crispr_ID: NZ_LT632322_10

• CRISPR_ID: NZ_LT632322_10
• CRISPR_location: 1667949-1668057
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT632322_10

Consensus_repeat	Method
CTTGCGGGAGCTCTGGCAATCCCAC	CRISPRCasFinder

spacers of NZ_LT632322_10

>10.1|1667974|59|NZ_LT632322|CRISPRCasFinder
GGCGCTTTGCGCCTCTGGATGCCTCGCTCACCGCGCGCCCTGCGCGCTTCGCGCTTGGC

CRISPR arrays and Neighbor proteins around NZ_LT632322_10

CRISPR arrays

The CRISPR arrays of NZ_LT632322_10

>merge|NZ_LT632322|10|1667949-1668057|CRISPRCasFinder
CTTGCGGGAGCTCTGGCAATCCCACGGCGCTTTGCGCCTCTGGATGCCTCGCTCACCGCGCGCCCTGCGCGCTTCGCGCTTGGCCTTGCGGGAGCTCTGGCAATCTCAC

>NZ_LT632322|10|8|1667949-1668057|CRISPRCasFinder
CTTGCGGGAGCTCTGGCAATCCCAC	GGCGCTTTGCGCCTCTGGATGCCTCGCTCACCGCGCGCCCTGCGCGCTTCGCGCTTGGC
CTTGCGGGAGCTCTGGCAATCTCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632322.1|WP_071706010.1|1664133_1664607_+|TRAP-transporter-small-permease	unknown	unknown	gnl|CDD|225632
NZ_LT632322.1|WP_071706008.1|1662102_1663131_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl|CDD|176195
NZ_LT632322.1|WP_071706012.1|1665877_1667209_+|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl|CDD|225930
NZ_LT632322.1|WP_071706013.1|1667225_1667801_+|class-II-aldolase/adducin-family-protein	unknown	unknown	gnl|CDD|376358
NZ_LT632322.1|WP_071706154.1|1658600_1659800_-|CoA-transferase	unknown	unknown	gnl|CDD|367110
NZ_LT632322.1|WP_071706006.1|1657190_1658486_-|citrate-transporter	unknown	unknown	gnl|CDD|225407
NZ_LT632322.1|WP_071706011.1|1664603_1665869_+|TRAP-transporter-large-permease	unknown	unknown	gnl|CDD|224509
NZ_LT632322.1|WP_071706009.1|1663144_1664137_+|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270321
NZ_LT632322.1|WP_071706153.1|1656700_1657141_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|239530
NZ_LT632322.1|WP_071706007.1|1660136_1661897_-|PrpR-N-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|377668

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT632322.1|WP_071706010.1|1664133_1664607_+|TRAP-transporter-small-permease	gnl|CDD|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	7.21458e-34
NZ_LT632322.1|WP_071706008.1|1662102_1663131_+|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl|CDD|176195	cd08233, butanediol_DH_like, (2R,3R)-2,3-butanediol dehydrogenase. (2R,3R)-2,3-butanediol dehydrogenase, a zinc-dependent medium chain alcohol dehydrogenase, catalyzes the NAD(+)-dependent oxidation of (2R,3R)-2,3-butanediol and meso-butanediol to acetoin. BDH functions as a homodimer. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. The medium chain alcohol dehydrogenase family (MDR) have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit.	5.14998e-98
NZ_LT632322.1|WP_071706012.1|1665877_1667209_+|four-carbon-acid-sugar-kinase-family-protein	gnl|CDD|225930	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown].	4.12746e-95
NZ_LT632322.1|WP_071706013.1|1667225_1667801_+|class-II-aldolase/adducin-family-protein	gnl|CDD|376358	pfam00596, Aldolase_II, Class II Aldolase and Adducin N-terminal domain. This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.	7.03468e-48
NZ_LT632322.1|WP_071706154.1|1658600_1659800_-|CoA-transferase	gnl|CDD|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	1.42801e-155
NZ_LT632322.1|WP_071706006.1|1657190_1658486_-|citrate-transporter	gnl|CDD|225407	COG2851, CitM, H+/citrate symporter [Energy production and conversion].	1.1694e-134
NZ_LT632322.1|WP_071706011.1|1664603_1665869_+|TRAP-transporter-large-permease	gnl|CDD|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	7.80068e-118
NZ_LT632322.1|WP_071706009.1|1663144_1664137_+|TRAP-transporter-substrate-binding-protein	gnl|CDD|270321	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the periplasmic-binding component of TRAP transport systems such as SiaP (a sialic acid binding virulence factor), TeaA (an ectoine binding protein), and an uncharacterized TM0322 from hyperthermophilic bacterium Thermotoga maritima. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.87679e-117
NZ_LT632322.1|WP_071706153.1|1656700_1657141_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein	gnl|CDD|239530	cd03446, MaoC_like, MoaC_like Similar to the MaoC (monoamine oxidase C) dehydratase regulatory protein but without the N-terminal PutA domain. This protein family has a hot-dog fold similar to that of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	1.67718e-48
NZ_LT632322.1|WP_071706007.1|1660136_1661897_-|PrpR-N-terminal-domain-containing-protein	gnl|CDD|377668	pfam06506, PrpR_N, Propionate catabolism activator. This domain is found at the N-terminus of several sigma54- dependent transcriptional activators including PrpR, which activates catabolism of propionate.	1.81856e-26

Protein sequences

>NZ_LT632322.1|WP_071706013.1|1667225_1667801_+|class-II-aldolase/adducin-family-protein
MQPEQQIKEMILYGKILFERGKVTGSAANMSIRCGEEIYITRSGSCFGTLTEEDFACIDRKGKSRNGIQPSKEWPLHWIYYESKLGQNAVIHTHSLYATLWSTIAPEDAKSVVPSITPYLQMRIGNIARIPYAPPGSEKLFSLAKQYMSLADGFLMERHGLLVGGKDMENAFYNAEELEYSCQIAWEMRRA
>NZ_LT632322.1|WP_071706012.1|1665877_1667209_+|four-carbon-acid-sugar-kinase-family-protein
MSILMGIIADDFTGGSDAASFFANHGIPTFLSNGIPKDPSLRKKWSGDHHCVIVIAQKIRSIAAEEAVAHALDACCWLRKEGAEKLFYKYCSTFDSTPKGNIGPITDAILEAFDYPYTFLAPGLPVNGRTVEQGILKLYGVPLAETHMKNHPVNPMWDSRIAELMRPQGKYPCIELDRNNLYQSREKIDEYVKTQLSKTSNAQGKSGPYYVIPDYTKAKDADQLVATYSDCDFWTGGSGLNDAFSAQFLKQKNIDATSTEERVPGKSILFSGSCSEMTLQQIAHYRLRYPNKAVQIAVREVMEGNPEEKIWEKALSIGDGVLIYSSDDASGRSALAKVYNQEEVSNRLEKLMGRLAQRAYAAGFNKLIIAGGETSGAITTALNFSTYQIGKSIAPGVPVMIPVENEKARLILKSGNFGQKNFFEEAISFLAPEIESGRLESAT
>NZ_LT632322.1|WP_071706011.1|1664603_1665869_+|TRAP-transporter-large-permease
MNTALLILIVFLILLTMGLEVGFAVTASALAAAVMLKIPVAVVAQRYFTAVDSFSLMAIPLFMVAGSIMSKGSLTKRIIDFTLSFMGNVKGALCQVVAISGMIMGGISGSGVADTAALGALLHPEMKRKKYDPEFSAALIAASGSIGLIIPPSVAMIIYGVTTQSSIGDLFIAGIVPGVLISLAFMLYSFVVAHKEHYPVEGSSSWAERWDKFKKAIFSLIMPLIIIIGIRGGFFTPTEGGAIISAYALLVSMFIYKDIKLADLPEIFFDAALSTATIALIICGTSLLTWILAYENIPQMLTQAVLSLTDNKIILIILIQSILLLTGMVIDSGPAIMLLAPILAPIAKQIGMSSVQFGLMMVISLTTGLLTPPVGTAMYVSSNISKIPVQRLAKRLVPFVLIMTVMSLLIAIFPIFSEILL
>NZ_LT632322.1|WP_071706010.1|1664133_1664607_+|TRAP-transporter-small-permease
MKKLNDTIQSILYYLLAFMICLMTVIVVLQVFFRYVMSSPLTWSEELARYLFVWITFLGIAIAIRKKAHVAIDLVVEHLPKMQQRIIRIINTVMILLLGGIIVYGGVQLMKIGEIQKSATLLLPMSLVFSAIPVSGVFIVLFSIEDLLSYFSKGEKK
>NZ_LT632322.1|WP_071706009.1|1663144_1664137_+|TRAP-transporter-substrate-binding-protein
MKRAKFIFVCLTVLLLCVGCGKPKEQAEVNLRLGHIQSAKDIWHKASLVFKEELEKRSGGKITATIYPSSTLGGDRDIVEGMQLGTIDMGLIAGVLGNFEPSIQLFEIPYLMTNEQEYETIVKGEVGGIIVERLRQRAGVHILDFWDRGPREVSSNKPINTIQDIKGLKIRIPEIQAMEAVWSAMGASPTTMAWGEVYTALEQNVIEAQENPVPFMYSGRIQEVQKYIAMTDHKFEYVTLSISEKTWQSLTEEQQKIVREAADAATKYQNDTVNQVAKENLQEMIDAGMKITYPDKKEFQDAAKEASRIYGESVDADLYNKIIQDLEAMK
>NZ_LT632322.1|WP_071706008.1|1662102_1663131_+|alcohol-dehydrogenase-catalytic-domain-containing-protein
MKACYVVSPEKVEIKNIEKPVIDEKEVLIRVHYAGVCGSDLHLFHGTHPFRKPPEILGHEVVGEIVEIGSKVTDLRIGDRVTVEPHLGCGQCELCQSGNENLCRTKIAPGSAKWMGTFVNYFKAPASKTHRLADKVPDEIGVLIEPFAVAVHAINLISIPQRESIVILGSGTIGLFTVVAAKAAGFKTIIATDTQQFNRDMAMQFGANITLDPLNCDVAEEVKKVTDGKGADVAIVAAGASNIIDQASSSVRKRGEVVLVAMITEKIPVYSYSFVFNEQKLIGAMTYRPQDFKEAVDLVNNGLNLDGFVTQIFPIHQTQEALDTLAQKKENVVKVLVDFHKE
>NZ_LT632322.1|WP_071706007.1|1660136_1661897_-|PrpR-N-terminal-domain-containing-protein
MHILFIIPYLSMKKDVQSILKRYPYVEASYAVGNVEGSIAITEDILKHTSIEAIISRGGTAEILRAHFSIPVFSIPMTSNDLGKTLYSIKTDKKVALVGYPTITMCAAYLETKNFGREDIYTVTQSDKIPEVIKTIKEKGYDLLLCDVISSEVAASFQLETKILLSSLENIQLSIDEAVYFYSQRRAGLQAETIQHTILKERDIYYVSINNMGKVISSNLPGHVVVDELMELVETFFVSYLLTSTTVRTAQLSDGQRLLFYLQKQIKAGTTYYIVTIKPNDFDQISKDYGIRLFRFNSHDPTQDARNLKTSLSLGQIRSKLRPFFAPQDDLVIYGERGTGKIDSALYIALNQKSRFPIAWMDAQSMNESMWSYFFDSFLPMASEPFTIIIQNIQQCDGEKIKRFSFLRRRDKIPHRLLFTLDAVDESLSSQLTLLEESPVVQFFRMPSLSERRSELVDIIDIYLKKYKIQTNKPIAGFEPKALDLLVNHSWPGNLEQLQRVLRTLFSKTTNYYLTEDEVSLLLFEENQWREAGTVGKIPYDRPLAEIIYNIVCQVMREEEMNQTRTAKRLQIGRTTVWRILKGKGH
>NZ_LT632322.1|WP_071706154.1|1658600_1659800_-|CoA-transferase
MSCHRALEDITVLDLTRVVAGPFCSSLLGDMGARVIKIEIPKKGDDSRSYGPIVNGESAYFALLNRSKYGVTLNLKSDIGKSMFLEMVKKADIVLENYRPGVMEKLGLGYDVLKQINARIIYGAVSGFGAWGPYSQRPGYDILAQAMGGLMSLTGEKGGQPTRAGNAMGDMLAGMNLTIGILAALHARKLTGVGQRVDVSLVDSIVVSLENAFTRYWYTGKLYERNGNAYAALAPYDTFQASDGLVVIACGNQNLFEKFCKNVVMKPEWLDDSRFSTNILRVENMNALEKLINAWSIHYSVEDITTRALKAGVPAGPVYDLSQIVKDAHIAGAREMFPTMHHPVIGDMPVNGDAIKMTDTNPEIIKPSPLLGEDNSSIYQEFLGLSKCELKRLSEEGVI
>NZ_LT632322.1|WP_071706006.1|1657190_1658486_-|citrate-transporter
MLAIVGFLSIIAVLVLIMTKKLSPMLTLIAVPMIACIIIGQGAKMGEFVTDGLKSVASTGVMFIFAVLFFGIMGDNGCFGRIVDKVLRIIGTDPLKIAIGTLIITMCTHLDGSGATTFLITVPALLPIYDKIGMDRRNLATIVAMGAGTMNILPWGGPTIRAATALEVSLTELYNPMVIPQICGLLACFVFTILIGRGEKKRLSDSLSHIVLEDKMLSEEEQILLRPNLFWFNLLLILTTIIILVWGILPPAGCFMAATLIAMLVNYPDGELQRKLVDTHAEAAMMMASTLFAAGVFTGIMKGTGMLAAMAEGLVSILPASLASHLAFALGFTSMPLSLAFDPDSFYYGVLPVLAATGEAAGITALAMGRAAICGQITVGFPISPLTPSTFLLTGLSGVDLGEHQKHSFLYLWAVSLVVLGSSVIMQVIPF
>NZ_LT632322.1|WP_071706153.1|1656700_1657141_-|MaoC-family-dehydratase-N-terminal-domain-containing-protein
MTYLDIDIGDEFLSPSRTVSESDLFQFAGLTGDLNELHTSEVFAKTTQFKKRIAHGMLILSIANGLYMRSNIFNSSVFLGIKNWKSTAPVFIGDTIHLKLKILSKRPTKDGKRGIIAMQYNVMNQNGLSVAEGEFTRMVTLPSMGK

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	290473-290490	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	310378-310395	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416065-1416082	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416120-1416137	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416175-1416192	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416230-1416247	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416340-1416357	0	1.0
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	358369-358386	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	290473-290490	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	310378-310395	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416065-1416082	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416120-1416137	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416175-1416192	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416230-1416247	0	1.0
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416340-1416357	0	1.0
NZ_LT632322_9	9.1|1389957|58|NZ_LT632322|CRISPRCasFinder	1389957-1390014	58	NZ_LT632322.1	1389828-1389885	0	1.0
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	290308-290325	1	0.944
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	290363-290380	1	0.944
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	290528-290545	1	0.944
NZ_LT632322_2	2.2|358204|18|NZ_LT632322|CRT	358204-358221	18	NZ_LT632322.1	1416285-1416302	1	0.944
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	290253-290270	1	0.944
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	290308-290325	1	0.944
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	290363-290380	1	0.944
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	290528-290545	1	0.944
NZ_LT632322_2	2.4|358314|18|NZ_LT632322|CRT	358314-358331	18	NZ_LT632322.1	1416285-1416302	1	0.944
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	343878-343895	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	606723-606740	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	606778-606795	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	606833-606850	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	606888-606905	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	606943-606960	2	0.889
NZ_LT632322_2	2.3|358259|18|NZ_LT632322|CRT	358259-358276	18	NZ_LT632322.1	683032-683049	2	0.889
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_LT632322.1	652062-652087	2	0.923

1. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 290473-290490, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

2. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 310378-310395, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

3. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416065-1416082, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

4. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416120-1416137, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

5. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416175-1416192, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

6. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416230-1416247, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

7. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416340-1416357, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

8. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 358369-358386, mismatch: 0, identity: 1.0

cgatggtggtagtagggc	CRISPR spacer
cgatggtggtagtagggc	Protospacer
******************

9. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 290473-290490, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

10. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 310378-310395, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

11. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416065-1416082, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

12. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416120-1416137, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

13. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416175-1416192, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

14. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416230-1416247, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

15. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416340-1416357, mismatch: 0, identity: 1.0

tgatggtggggatttagc	CRISPR spacer
tgatggtggggatttagc	Protospacer
******************

16. spacer 9.1|1389957|58|NZ_LT632322|CRISPRCasFinder matches to position: 1389828-1389885, mismatch: 0, identity: 1.0

gttcgtcagggtcctttggtccctgacatttcacgaaattcaccactcgtcagggacg	CRISPR spacer
gttcgtcagggtcctttggtccctgacatttcacgaaattcaccactcgtcagggacg	Protospacer
**********************************************************

17. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 290308-290325, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

18. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 290363-290380, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

19. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 290528-290545, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

20. spacer 2.2|358204|18|NZ_LT632322|CRT matches to position: 1416285-1416302, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggggattcagc	Protospacer
**************.***

21. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 290253-290270, mismatch: 1, identity: 0.944

cgatggtggtagtagggc	CRISPR spacer
cgatggtggtagtaaggc	Protospacer
**************.***

22. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 290308-290325, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

23. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 290363-290380, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

24. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 290528-290545, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggtgatttagc	Protospacer
********* ********

25. spacer 2.4|358314|18|NZ_LT632322|CRT matches to position: 1416285-1416302, mismatch: 1, identity: 0.944

tgatggtggggatttagc	CRISPR spacer
tgatggtggggattcagc	Protospacer
**************.***

26. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 343878-343895, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggtagtttggc	Protospacer
*************  ***

27. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 606723-606740, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtaaggc	Protospacer
*********.****.***

28. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 606778-606795, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtaaggc	Protospacer
*********.****.***

29. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 606833-606850, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtaaggc	Protospacer
*********.****.***

30. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 606888-606905, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtatggc	Protospacer
*********.**** ***

31. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 606943-606960, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtaaggc	Protospacer
*********.****.***

32. spacer 2.3|358259|18|NZ_LT632322|CRT matches to position: 683032-683049, mismatch: 2, identity: 0.889

cgatggtggtagtagggc	CRISPR spacer
cgatggtggcagtaaggc	Protospacer
*********.****.***

33. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to position: 652062-652087, mismatch: 2, identity: 0.923

acacagtttcgctgtatagcagctgc	CRISPR spacer
acacagtttcgctgtacggcagctgc	Protospacer
****************..********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_KM007160	Lactococcus garvieae strain IPLA 31405 plasmid pLG42, complete sequence	33876-33901	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NC_015900	Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF18, complete sequence	1795-1820	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP016726	Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08A, complete sequence	28992-29017	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP021475	Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-4, complete sequence	2981-3006	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_LT599053	Lactococcus lactis subsp. lactis strain A12 plasmid pA12-4, complete sequence	20629-20654	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP027769	Tetragenococcus halophilus strain LMG 26042 plasmid pTHF, complete sequence	6542-6567	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP027784	Tetragenococcus osmophilus strain JCM 31126 plasmid pTO1, complete sequence	23614-23639	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP023007	Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence	34743-34768	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP021926	Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence	29315-29340	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_LT907987	Lactobacillus sakei strain T332 plasmid p332A2, complete sequence	44934-44959	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP043518	Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96 plasmid pSD96_06, complete sequence	21570-21595	4	0.846
NZ_LT632322_5	5.1|652126|26|NZ_LT632322|CRISPRCasFinder	652126-652151	26	NZ_CP027785	Tetragenococcus osmophilus strain JCM 31126 plasmid pTO2, complete sequence	17490-17515	4	0.846

1. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_KM007160 (Lactococcus garvieae strain IPLA 31405 plasmid pLG42, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

2. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NC_015900 (Lactococcus lactis subsp. lactis bv. diacetylactis plasmid pVF18, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

3. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP016726 (Lactococcus lactis subsp. lactis strain UC08 plasmid pUC08A, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

4. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP021475 (Pediococcus pentosaceus strain SRCM100892 plasmid pPC892-4, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

5. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_LT599053 (Lactococcus lactis subsp. lactis strain A12 plasmid pA12-4, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

6. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP027769 (Tetragenococcus halophilus strain LMG 26042 plasmid pTHF, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

7. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP027784 (Tetragenococcus osmophilus strain JCM 31126 plasmid pTO1, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

8. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP023007 (Pediococcus pentosaceus strain SS1-3 plasmid pSS1301, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

9. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP021926 (Pediococcus pentosaceus strain SRCM100194 plasmid pPP194-1, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

10. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_LT907987 (Lactobacillus sakei strain T332 plasmid p332A2, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

11. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP043518 (Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96 plasmid pSD96_06, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

12. spacer 5.1|652126|26|NZ_LT632322|CRISPRCasFinder matches to NZ_CP027785 (Tetragenococcus osmophilus strain JCM 31126 plasmid pTO2, complete sequence) position: , mismatch: 4, identity: 0.846

acacagtttcgctgtatagcagctgc	CRISPR spacer
gctcagtttcgctgtatagcccctgc	Protospacer
.* *****************  ****

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	348035 : 424895	74	Erysipelothrix_phage(42.86%)	transposase,terminase,portal,tRNA,holin,tail,head,capsid,protease	NA
DBSCAN-SWA_2	527613 : 539733	16	Streptococcus_phage(40.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_LT632322|348035:424895|DBSCAN-SWA
CATGAGAATGAAACGCTTCTATATGCCGACGCTGCGCGAAGTGCCGGGGGATGCGGAAGTCCCCAGCCATCAGCTGCTTCTGCGTGCCGGCATGATTCGAAAAGCCGCTTCCGGCATTTATACGTATTTGCCGCTTGGCTATCGCGTGGTGCGCAAGATTGAAGAGGTGGTGCGCGAGGAGATGGATCGGGCGGGCGCCCAGGAAATTCGCGTCTCGAACCTGCAACCGAAAGAAATTTGGGAAGCCTCCGGTCGTTGGGATACCTTCGGCCCGGAGATGTTCAAGTTGACGGATCGCCATGAAAAAGAGTTTGCGCTCGGCCCCACGGCGGAAGAATATTTTACCGACTTGGTGAAAGAAGAATTACGCAGCTATAAACAGTTGCCGCTCAATCTCTATCAGATCGGCTGGAAATACCGCGATGAGAAGCGTCCGCGCTTCGGCATCAACCGTTCCTGCGAGTTTTTGATGAAGGATGCCTACACCTTTGATATTGATCAGGAAGGGCTGGAAGCCGCCTATCAAGTGATGTGGGATGCCTATGTGCGCGTTTTTGATCGCCTGGGCATCAACTACCGCGTCGTGCAGGGCGATTCGGGTGCCATGGGCGGTCACGTGTCGCACGAATTTACCGCGCTTTCCGAAATCGGGGAGGGCGTTATTGTCTATGCGGAAGGCGGCTATGCGGCGACGGATGAAAAGGCTTCTATGCAGAAGCCGACGTATCCGGCCGAAGAACCCTTGCCGGTCGAGACGCTCGACACACCGAATGCGCATACCATTGAGGAATTGGAAGACTTTCTGCACATCCCGGCGCACAAGATGATCAAGGCCATTTGTCTGCGCATCAGCGGCGAACCCGTGTTCGTTTTTATGCCGGCAGAGCGCGAACTCAACATGTCCAAGCTCATTGCCTATTTGCATACGCCGGAGCATGAAATTGAGATGCTCGATGATGAGACCATCGAACGCGTGACGGGCGCCCCGGCAGGCTTTACCGGCCCGGTCGGTCTTCCCGATACGGTGCGCACGATTTTCGATGCCGCCGTCACGACGCGCGAGAACCTCGTCTGTGGCGCGAATAAGGCGGATACACACCTGAAAAATGTCAATTTCGGCCGTGATTTTGACGGCGAGATTGCGGAGGACCTCTGGATGGTTGCCGAAGGGGATCTTGATCCCATCCACGGCAATCCGCTGCAGTTTGCCCGCGGTATCGAAGTGGGCAACATCTTCCAGCTCGGAACGAAATATTCCGAAGCCCTTGGCGCCACCGTATTGGATGAAAACGGCGTCGCGCGTCCGCTCGTGATGGGCTCGTACGGCATCGGCGTAACCCGTGTGGTTTCGGCCATCATCGAACAGAATCACGATGAGAAGGGCATGATCTGGCCGCTCATCGCTGCGCCGTATCATGTGATGATTACCGTGATGAAAACCAACGACGAAACCCAGATGCAGCTTGCCGACGCGCTCTACGAGCGCCTCGAAAAGGAAGGTGTCGAGGTGCTTCTCGACGACCGGGATGAGCGTCCGGGCGTGAAATTCAATGACCGTGACCTCATCGGCATTCCGCTGCGCATCACCGTCGGCCGCAATGCCGCCGCCGGCATGGTGGAATACTCCACGCGCCGCGAGATGACCAACGAGGATGTGTCCGTGGAGGAGGCCGTTTCGCGCGTGGCTGCCGCCATGGAGACGCTAAGAGAGGTATAACGTTCGAAAAGGGCGCCGTTTCATGCGTCCTTTCCGCCAAGGGCGCTACAGAAGTAGAAAAGCGGATAGAATTTAATAAATCAAAAGGAGCCTTAACGGCTCCTTTTTTTGTTGAGATTGTTTGATTCGGTTTTGCGCTACGGGATGAGCAGGCTGACCGTGTAACTCACCAGATTGGCGAGTATGGCATAGCGAACGGGATGCTGTTCTTTCGGCAGCTTTCTACGGTAGAGAAGAGCTTCGATGCCGAGGACAAGAGCTTCCAGGGGAAGCAACAAGACAGGGCGCATGACCGGCATGATGCCGGTTGTACCCAGCCGGAAGCCGATGAACCACAAGCCAAGATGGAGAAGCGCCTGCGTGCCGAGATTCACGAGGGCGATGTAGCGAAGCGACGCTGTCTCTCGGATTCCCATCAGATAGGCGACGGCCAACTCAATCAAGATTGTGCCGGCAATCAGCGCCAGCAGCTTCGGAACATCCGCCAGATAGTCATAGTGGAAATGAATGTCGGTGATGCGATCTTCTTTTATGGTGACGGTATACTCATTTTTTAAAGCATGACGCGTGAGCGGCGCACTCATCAAAAAATGATCCGCTTTCTCGTCATAAAGCAGAATGCGAAAGGTTTCCGGCGGATAGTAGCTCCAACAAAAATCGCGAGGAGCCGCTTCCGCCACATAGCCTAAAAAATAATGGTCTTCGGGAAGTGAAAACTGCTGAAATTTTTGTTGAATCGAATCCGGCGCATCGGTGGTCCAGACCGCATTCGCTCTCCATGGGCCATATTCCGCAGAGGAAGATAATAAGGTTGCGTAATAGCGTGTGTCGGATCCGGCGATATGCACCGATACGTAGGGCTTAGGCCCCATATCGGCGTGGGATAGGGAAGGACACAGCAAAAAAAGAAGCAGCAACACAATAAAAAAGCGACGTTTCACGGCAACCTCCTTTTCCGCATTCTTAAGATCATTATATCCGTTCTTTAAGATCATTCTAACGGAAGGGAAACATGGAGAAAACTGAAAACGTCGCGGTTTCTTGGTTTGTTCAAGCGCGTTAAATCGATTGACGTAGATTGTGCAATGCTGTGAATTCCTCAAGCATGCTTACGCGCTCATGTTGGAGGCATCGGCCTGCTGTTTCATGGGCATGGCAAGAGTTCCCGGCTTGGGCAGGCGCAGTTCAAATTGCCCGACCACAAACGATGAGATGAGGGTCGTCAGAAACGACCACAGCAGGTTTTGTGCCGGCAGGTAGATGAAGAAGGATAGTCCAAGGACGACCGCGTCGCTGATGAAGTAGGCGCTGCTTAACGAAAGCGACGTGCGCTTTTTGAGAATCAGTGCAAAGCAGTCATCCCCACCGGCAGCGCCACCGCGGGTCACAACCAGACCGCATCCTGCACCCAGAAGCAATCCGCCGACGATGGCGGCAAGATGGGGCGCATTCGCAAGGGATGGTAAAACCGGGCCTATTGCAGCAAAAAGTGTCCAAGAGCCGGCATAGGCAAGTGTTGAGAATACAGCTTTTTTCAGGAATCCGCGTTCCAAGAGAAGAATGCCCAACCCGTAAAGGGAAAAGTCCAAAACGATGGACAAAATGGCCGGATCCAGGCCAAAAACCTTATTCAGCAGAACAATGCTGCCGAGCACGCCGCCTTCGGTAATGCGGGACGGAACATGGATGTTATAGATGGCAAAGGCCATGGTCAGGTTTCCCAAAACCATCAGAAAAAGATCCAAAACGGATATGTTCATCCACGCCGCGAAACGACGTAGCAGTTGCATGGGCTGATTCTTCCATGACTTTTTCGACAAGAATTTCATAAAGACACCTCGTTTTCGTTGACACGGTGTCTTCCGAACCAAAAAAAGATTGCCTTGGCCGTGAGAAGACTCCGTGCTGTACAATCGTGTGGTGGTTGATGCTGTTGTTTGAAATTCTTTCTTGTAAGAACTCTGTCTCCCTCGCCGTTTAATGATTCATCGTGCCACATCAGGCAACGCATGAACCCGCTCACAGCCAGGTGTTCAGATAAAAACTACCGCGTAGCGGCACCCACAGGATGTTGCTCATTTCTGTTCCTGCAATAGTATAACACAAATTTTTATTTTGGGAAAGCCTGCGCCGGCATCCATTCGCGCGCCGCCGGCTTCGCCTCGGCAAGGTGATGGAGGTTGGCGTATTTCCGGCTCGTCGAAGATGCGGCGCGCGAACGGATGTCGGCGCGTGGGGGCGCGGGCGAGGTGTGGTGCGGGGGGACGTGTGAGGAAGCGGGCGGGGAAAATAGGCGGTGCGCCGCTGGGAACACCGTTGGCGGCGCGTTTGAAAGGTGGTGCGCCGCTTGTACCGCCGTTGGCGGCGCGGTTCTGAGAGGAAGCCGCCTTCGGCGGCGTTTTCAAACCGCCGGCCGCAGGCCGGCTCCTTATCTTAATAGAGTGGAATCGTCAAAAAAGCGAAACAACTCTACACTCGTTCGTCGTCCTGTAGAGTGGATTGCTGAAAAAGGCGAAACCACTCTACATCCGCTCGTGATCTTGTAGAGTGGAATGGCCAAAAAGCCGAAACCACTCTACACCTGCTCGCAACCCTGTAGAGTTGAATTGCCGAAAAAGCAAAACCTCTCTACATCCGCCTAAACATCGGTAGAGTGGTTTCGCGATAATTGCAAAACCACACGATTTCTATGACACGCCAAGAAAAATAAGGCGGAGCGCCGCCGGACCCGCCGTTGGCGGCGCATTTTCCAAGAGGAAGCCGCCTTCGGCGGCGTTTTCAAACCGCCGGCCGCAGGCCGGCTCCTTATTTTTGGAGCAAGTTACATCACTTCTGCGGACGATGGTGGTGGAAGTCTATTTTCGGCAAACCACCACCATCGCCGAAGCCGCAAGTGATGGTGGTGGAAGCGCGATTTTGGCAAACCACCACCATCGCCAAAGCCGCAAGTGATGGTGGTGGAAGCGCGATTTCGGCAAATCACCACCATCGCCGAAGTCGCAAGTGATGGTGGTGGAAGCGCGATTTTGGCAAACCACCACCATCGCCGAAGCCGCAAGTGATGGTGGTGGAAGCGCGATTTTGGCAAACCACCACCATCGCCGAAGCCGCAAGTGATGGTGGTGGAAGCGCGATTTCGGCAAATCACCACCATCGCCGAAGTCGCAAGTGATGGTGGTGAAAGCCCATTTTACGCAAACTCCCACCATCACCGAAGCCGTCAGTGATGGTGGTGGAAGCACGTTTTGGCTCAACCACCACCATCAGCGCAAAAAAAGAGGGGGAGGGTGCGCCCGTTGCTTCCCTATAACGATAGCGGATCGCCGGCCACAGGCCGGCTCAAAAAGCAGACACCACATTTGAACCTCCGAATGTCGCGAGTGGACTTTGCGTGCCATTGTCCTGAAAAAGGGTAACCTTATCCATAAGAACCGCAGATTCTTTAACAACCGCAGATTCTTTAAGAACCGCAGAATCTTTCATCCTGAGCGGGTGCCGTGATAAGAACCGCAAACAACGGACCATTCAGCGATCTTGAACGGATGACACACAATCACATCCGCAGCCCCAAGCCCAGAATTAACGGCACCCCAACCACAGAATCGACAACACCCCAAACACAGAATCAACAGCTTCCCATAAAAAAAGAAGCGGAAGGAGGAAATAATGCAAAGAACTACGAAACAGCCGCGTCGGCGCTGGATGCAGATTGCAGCGAGCATTCCGAATCGCGAAAAGGAAGAGGAACGCCGCCAGGATCTGGAGCGCTTTCATGCCAAGGTGGGCGATGAGAAGGAATGGATCGTCATGCGCCTGGACGACGTGGATGCGCTGATCGAACAGCTGACTCGCGAGACGGAAACCATCCGGGAGAGCCTGGATCGTCCGCACCATGAGAGGGTGTCGAGCCTTGCACCCCTGACGGAAGCCGGGAAACAGCATCTGTCGAGAAAACGGCTGCTCCGCTCTTCGGCTGAACTCGATGTACTTTTGCTGGAAGTGCATCGGCATCCCGTCTTTCGGGACATCGTGGCGGATATGCAAAATCTCACCGTCCCGGAAACGACGCTTCCTGTGGAAAACGAAAGCAGCGTGGTCGCCTCGCGCAAGATGCTGTCTATTCGTGATCAGCTAAGCGATCTTTTGGACAACTTGTATCGCCTGCGCCGCCGGCTTCGTCGCGAACTGCTTCGCCTTGCCCGATAATTGGTGCGGGCAAAGTTGTGTGCCGATTATGGAACATATTTCCTTCAAAGCCCTCCGATAGGCTACAAAGCAAAAAGGAAACTGCGGAGGGGACTGCGTTGTGATCGGAGCAGGGAAATCCGCTGCGATAGAAGGAGGAAATAGCATGGACGAACAAGAGCGTTTAGAACAAACGGAAGAATGGAATGAGGATGCTCGGAAGGCACAAAGTCCTCATTATGAAGAAGCTGCGACACGTCGCATCGTGAGGGAAGAGATTGCGCGCAATTACCGGCCCAAGGGAAGCGCGGCGCGTGCCGTTGCGCTGGTGCTCTGCGGCGCCCTTCTCGGTGCGGGCGGCGGCGCGGCGTTGGTGGCATCGGGCAACATTCCTCTGCCGCAGCAACAGGAACAGGCGGCAAGTGCCACGACCAACGGCAATATCAACATATCTTTAAAGGAAGGCCAAACCACCGTGGAAAACGCCATTGCGGCCAAGACCATCCCTTCCATTGTCGGCATCACGACCATTGCGAAAAGCGTCAGCAACAATCCGTTTTTATATGGAACTCCCCAATATTCTGAATCCGTGGGCTCCGGCGTGATCGTTTCTGCGGATGGCTACATTTTAACCAATGCGCATGTCGTCAACGGCGGCAATGCGAAGACGGTACGGGTTCGCCTTTCCAACGGCGAAGAGGCCGAAGCGAAGGTTCTCTGGGCGGATCCCACGCTGGATCTGGCCGTCATCAAGGTGGAAAAGAAAAACTTGCCGGCCATTACGTTCGGCGATGCCTCCAAGGTGCAGGTAGGCGATAAGGCTGTTGCCATCGGCAATCCGCTGGGACTCGACCTGCAATCCACCCTGACATCGGGATACATTTCCGGCCTGAATCGTTCGATTACCCTCCAGGATGGCAATATCATGGATGGCCTAATTCAGACGGATGCCGCCATCAACGGCGGAAACTCGGGCGGTGCCTTGCTCAACGCCAAAGGAGAGCTCATTGGCATCAATACCGCCAAGCCTGCCTCGGCGGACGGCATCGGCTTTGCCATCCCGGTGTCCACCGTCAAACCCATCGTGGACAAAATCGTCGCGGACGGCACCTACACGCCGCTTTACATGGGCATCAACGGAGCCAACACAAAACTGGTGGCGGCAAGCGGCGTCGAAGGGCTGCCCACCGACAGCGGCGTCGTCGTTCGGGATGTCGTTGCCGGCTCGCCTGCAGCGACCATGGGCATTGAACCCTACGACATCATTGTCGCGATCAACAACGAACCCGTGGAATCCATGAACACCTTAAAGACGCTGCTGCTCAAATACAAGAAAGGCGATACCGTAGACGTTACGTATTACCATGGCCGCGACAAGAAAACCGGCAAGATGACCTTCACCGATTTCTCCCCGGAAGCCATACAGCGCTAACCCGCGCCCCGGCACCCTTCCTTGTGCCGCCGGCTTCGCCTCGGTGAACAACGTGTGGAAGCCTTGCTCCCGGCTCGTCGAAGAAGCGGCACGCGAAAGGGTGCCGGGGCGGCAGGAGTGGCGGGCGAGGTGCGCGGCGGAGAACGGGGGTGCCTCTGGCGCGTGACAAAATATAGAAGAAAGAAGCGACGGTCCCGTCGCTTCTTTCTTTCTGGCATCGGCCCTTCTTTCTGTACCAAGCCCACGCGTTTTACGCCCATCGCGAAACGCCACGCATATTTCACCAAAAAAAATGGAGAATTCGCAAAAAAGGGCATAATGATAAGGACAAAGCTACATCAACCAATAGCAACAAAGGAGGAAATCATGACGATGGCTACCACCACAAAACAACCGCACCCTGCTCAACACACTGCGGAAAACCCGGCGCTTCCCGAGGCACTTGCCCCTCTCTTTACTCCGTGGAAAATTGGAACCGTCGAAATCAAAAATCGCATCGTACTCACGTCGATGGGCGGTACCAATCTGCTGGGATGGATGGAAAAGAACCACTTTGACGAAACGGGCGCGCATTTTATCCGGACGATCGCGGAAAACAATGTGGGTCTGGTTCTACCGGGATGCCAGCCGGTGTACAACCCCATGTTCGGCCAGTGGCTGTATAAAAATAAGCGGATGTACGATGATCTGGCCAAATGGCTGCCGGCATTCCATCAAACGGGCGCGAAGCTTTTCGTGCAGCTGACAGCGGGCTTCGGCCGCTCGTTCACGATTTCCCCCATGATGGAAACACTCTATACGAATCCGGTTTTGCGTTTCCTTTCCAAGCCCGTGATGAACCTGGATAAGATTACCGCCTCGGCTTCGGAAGCGCCCAACCGCTGGTCGGACAAAGTGCCATCCCGCGCCATGACGGTCGCAGAAATTCAACAGATGGTGGAGGCGTTCGGCAAGAGCGCGAAGCTGCTTAAGGATGCCGGGGTGGATGGGGTGGAAGTGCATGCCGTCCATGAAGGCTACCTGCTGGATCAGTTCACCTTGAAATACGTCAATCACCGCACGGATGCCTACGGCGGCAGTCGGGAAAATCGCTATCGGTTCCCGGTGGATATTGTCCGGGAGATTAAGCGCGTCTGCGGCGAGAATTTTCCGGTTTCCCTGCGCTATTCCGTCGAATCCAAGACTAAAGGATTTCGTCAGGGAGCTCTTCCCGGGGAAGAATATACCGAGGTCGGTCGGGATATGGAAGAGTCGCGGTGGGCGGCGCGCTACTTGCAGGATGCCGGCTATGACATGCTCAACTGCGACAACGGTACCTACGATGCTTGGTACTGGTGCCATCCGCCGATTTACATGCCGGAAAACTGTAATTTGGATGAGGTCAAGGAAATCAAAAAGGCCGTGACGATTCCCGTCGTTCCGGCCGGGCGCATGGATCCCTACGTGGGCGCGAAGGAAGTGGCCGCCGGCACAATTGACGGGGTCGGTTTTGCGCGTGCGTTTTTGGCGGATCCGGAGTGGGTGACCAAGATCCTGGAAGGACGAAGCGAGGAAATTCGCCCCTGCATTTGCTGCCACAACGCCTGCTTCAACATGAGCAAATGGAAGGGAACGCCGAATATGCAGGAGTTGCAGGATTCGCTCCATTTGGCGCGTTGCGCCGTGAATGCGGAGACCATGCAGTGGGACAAGCATTACATTAAGAAGACGGATGCGCCGAAGACGGTGCATATCATCGGCGGCGGGGTTGGCGGCATGGAGGCGGCTCGCGTGCTCAAGTTGCGCGGTCACAATCCGGTGATCTATGAGCAAACGGATCGTCTCGGCGGTGTCGTGATTCCGGGAGCGGCCGAGTCCTACAAGAAGCCCATGCGCGACCTTTTAGCCTGGTATCGGCAGGAAATGGAGCGTCTGGACATTCCCGTTCATATGAATCAGAGCATTGCGCCCGACCACGACTTCGGTACGGATCCGGTTATTGTTGCGACCGGTGGAAAGCCCATTAGCCTTTCGCGTGTTCCGGGCTTTGACCGCACGATCGAGGCCACCGATTTTCTGCGCGCGCTGGAAGGGCGTCGGGAGGAAGAGGGTGTCGCGGTCAAGAAGGGCGTCGGCCGGCGTGTCGCGGTCATCGGCGGAAGCCTTACCGGCTGTGAAATTGCCTACGAGCTGGCCCTGCAGGGCAAGGAGCCCTTTATTCTGGAAATGAAGGAAGACCTGATTGCGACAGAAGGTGTCTGTCTGGCGAATTCCTCTTACCTGCGCGAATGGTTCGCGCTGCATAAGGTCCCGGTCTATTTGGAATCCACGCTGGTTGAGGTGAAGGAAGACGCGGTTACGTACAAGGATGCCTCCGGCGCGTTGCACGAGGTGCCTTGCGATTCCGTCATTTCTGCCGTTGGGTATCGTCCGGATCCCTTGCTGGACAAGGCTCACACCGGCGCGCAGACGTATTTTATCGGCGATTGCGCTGGCATCGGCAACATCAAAACCGCCGTCTGGCAGGCGTATGAAACGGCGATGAAAATTTAGTTCCATCCTATACATTTGTAAATGATTTGAGACCAAGAACGTGAGAGAATCTCCAGTATGATGCCGTATTGCTGACGGGTTACCCCGTCAGCAATACGGCGTTTTTTGACAGATGTTAGCCACCTAAGGACCGCTTACGACAAGTTTTTTCAAGGGATCGTAAGGCTTAAGCAGATAAAAGTTCATTGCGCGGAAAGTGGTGATGGTTTAGCGAAAACGCGTTTCCGCCACCATCGTTTTGCCCTTGGCGATGGTGGGGATTTAGTGAAAACGCATTTCCACCACCATCGTTTATGCCTTCGGTGATGGTGGGGATTTAGCGAAAACGCATTTCCACCACCATCGTTTGTGCCTTCGGCGATGGTGGTAGTAGGGCGAAAACGCATTTCCACCACCATCGTTTATGCCTTCGGTGATGGTGGGGATTTAGCGAAAACGCGTTACCACCACCATCGTTCATGCTTTCGGCGATGGTGGTAGTAGGGCGAAAACGCACTTTCCCCACCATCGCCGCAATAAGGAACCAACTTGCAGTTGGCATTGAGATGGCGCCTTTTTACAATAGAGACGCCAGAAGGAACCGACCTCCGGCTGGCGCTATTGTGACCTCTTTGCTCGGCGATGAAAATTTAGCACCATCAGTCCTTGCCGTCGTCGCCACCCTGTGCTATACTCATAAAGCTATGCACGAAAACTTGCAAAGAGAGGTGATCACATGAAACAAGGCATTCACCCGGAGTATTACGAAAACGCGACGGTTACCTGCGCTTGCGGTAACACGTTTACGACCGGTTCGACCAAAAAAGAGCTGCGTGTAGACGTTTGTTCGGCGTGCCATCCGTTTTACACGGGCAAACAGAAGACAGCAGAACGTGGCGGTCGTGTCGAACGCTTTAAGAAGAAATACAACATCGACTAACACAAGAGAACGGGCTTGCCAAAGCCTTACAAAAAACGACCACAGACGGCCTCGCCGTATGCGGTCGTTTTTTTGCGCCGAAGGCGGGGACGATGGTTGGCGAATTTGAGAGAAGGGGATGGCTTGCAATTTTGTGCTGATATGCGATGAATTGGCTTCCAAGTCCGCCTCACGGCTTAACCCTGTGTCCCTTTTTCTTAATTATTAAAATTAGGGACACAGCTTTTTGCTCAAGTGAGGTAAAAGTGTGTCCTTTTTTTAACTTTCGGAAATTAGGGACACAGGATTTTTACTCTAGCGGTGCAAAATGTGTTCCTTTTTGTGCTTTTTTGGATTTAAGGACACAAAATTTGCCTCGTCGCGGCCTAATCTTGTTCCCTTTTTTTCAATTATAGAAATTAGGGACACGGTTTTCACTTAAGTGAGGTAGAAGTGTGTCCTTCTTTAACACTTTCGGAAATTAGGGACACAATTTTCACGCTATGGAGGCACAACAGCGTGTCCGTTATTTCATTTTTTTGCATTTTCGGACACAAGCTTCCCAGAATATCCATTTCGATAGCCACGCCGCCAACGGCATTTCCAGCGGCGCTCCATATGGGTTGTCCTTCCAAACGCATGGCTCATTTGCAAAAAGTAGAGCCGCATACCAAACATCGTTACAATGAGAAGAGATCGACGCGAAGAGACCCTCGCGAAGAGAACGACGCGAAGGAACAGATGCGAAGGAACAGATGCGAAGGAACAGATGCGAAGAGGACGGGGAAGGCGACGTACGTCGAAGGCGTTGCGCAATACCGATGCGTAACAACAGGAGGCAGGATGAAGACCATCGCACAATGGGCGGCGCTGCTGCCACAACAGGAAGGCTACCTGGCGTTATCCTATGTATTGGACACGACGCCGGGTGCGCTGCGCGCAAAAAGCGGCGAAAGCCTGGATACGGCCGTTACCGAGCGCTATCAGGAAATTGTGCGGCGTCGCCTTGCCGGCGAACCGCTGCAATACGCCATCGGAGAATGGGAATTTTATGGGCATCTGTTTCAGGTTGATGCGCGTGCGCTGATTCCGCGTCCCGAAACGGAGCGACTGGTGGAGATGGCTCTGCAAGAGGACCTTGCCGGCAAGCTCGTTGCCGATATCGGCACGGGCACGGGGGCGATTGCCCTCAGCATCGCATTGGAGGCGCACCCGAAGCCGAGGAAACTGTATGCGACCGACTGCTCGGCTGACGCACTTGTCCTGGCAAAGGAAAATGCCGCCCGCCTTCTGTCATCGAGAGGGGGCATCCACGCGCAGCCAGCGTCCGCACAACCTGTACCGAACGATGCGTCGGCATCCTCACAAAACATGATAGAATGGGTGCTGGGCGACGGACCGTCGGCTCTGCCCGAGGCCGTGGACGTGTTGGTGTCCAATCCGCCCTACATTGATCCGCAGGAAAAAGAGAGCCTGCAGGATGAATTGCAGTATGAACCGGCATCGGCTCTGTTTGCCGGGGAACCCGGAAAGGGCGGTCTGGCCCTGTATCAGGAATGGATTCCGCTGTTGCCGGCAAGGCTGCAGTCGCACGGCGTGGTGCTCATGGAAATAGGAGATCGGCAGGGTGAGGCCGTTTCGAGCCTATTTCGACAGGCGGGATTTTCCGCTGTAACGGTGCATCCGGACTACACCGGCCGTGACCGCATCGTGCGCGCGACGCGATAGCCGCGTAGCCCACGCCGCCACGAATCGAATACGCTCCCCACACGAAACGAAGAGGAAAATCATGTTTGAAAGTTTAGAACATATTCAAAGCCAATTGCACGAGATGGAACAGCAACTTGCCGACCCGGCGCTGCTCGCCGACATGAATGCCTGGCGCAAAGTCAACCGGGCCTATGTCGAACGCAAGCCCATCGCCAAGGCCTATCAGGAATATAAGAAAGCCATCGATACCGCCGAAGAAGACCGCGAGATGCTGAAAGAAGTGCAGGATGCGGACATGGAAGCGATGTTGAAGGCCGATCTTGCCGAGCAGGAAGACATCGCGCAGAAAAAAGAAGAAGAGCTCAAGCTCTTGCTCGTGCCCAAGGATCCCAACGATTACAAAAACGTCATTGTGGAGATTCGAGCCGGCGCAGGCGGGGACGAGGCCGGACTGTTTGCCGGCGATTTATATCGCATGTACCACATGTATGCTGAGAAAGAAGGGTATACCACCGAAGAGCTCGATCGCACCGAACAGGGCATCGGCGGCATCAAAGAGGCCACCTTCATGGTCAAAGGGGAAGGCGCGTATTCGAAGCTCAAATACGAATCCGGCGTGCATCGCGTACAGCGCGTGCCCGAGACGGAGTCATCCGGACGCATTCATACGTCGACGGCGACCGTCGCGGTCTTACCCGAAGCCGAAGATGTCGATGTGGAGCTGAATCTCAATGATGTGCGCGTGGACGTCTATCGTTCCAGCGGACACGGCGGCCAATGCGTGAATACGACCGACTCTGCCGTGCGCGTCACGCACATCCCGACCGGCATCGTGGTGGCCATCCAGGATGAAAAGAGCCAGCTGAAGAACAAAGAGAAGGCGCTGCACCTTCTGAAGACCAAGCTCTATGACCTGGAACTCGAAAAGCAGAATCAGGAAATCGCCTCGGCAAGGCATTCCCAGGTGGGAAGCGGCGACCGAAGCGAACGCATCCGCACGTATAATTTTCCGCAGGGACGCATCACCGACCATCGCATCAACCGCACGATCTACCAAATTCATGAATTTCTGGATGGCGATATCGGCGAAATGATTGAGGCCCTGCAAACCGAAGACCAGATGAAAAAACTGGCGCTGGTCACGGACGACAGCGAGCAAGCATAGTAGGAGGACCCATGGACAAAGAGCAGTTTTTGAAGCAGTGGAACGAAAGCACCAAGCGTCTGTTCTGCAAGACCATTGAAACGGCAACATCCTTTGAAAAATATGCCGCCCTTTCCCAAACCATTATGGATCACATCACCGATGCCTGGATGGAAACGCGGGAAAAGACCAAGACCATGCGTAACGAATACTATTTTTCCGCCGAATTTCTGGTCGGCCGCGCGCTGGGAAACAACCTGCTGAATCTGGGCATTCTCGACGAAGTGAAAGCGGTTCTCAAGGACATCGGCATCGACTTTGAACAGCTCGAAGACGAAGAGGATGACGCCGCTCTCGGAAACGGCGGTTTGGGAAGGCTTGCCGCCTGCTTCATCGACTCCGCTGCCAGCGAAGGCTACCCCGTCCAAGGTTATGGCGTGCGCTACAGCCAAGGCATCTTTGAACAGAAATTCATCGACGGCTTCCAGCGCGAAGAAGGCGACGATTGGACCAAAAAAGGCGATTTCTGGTCGCAACGTCGTGAAGAGGAAGCCAAGCTCGTGCGCTTCCGGGACGAAACCGTGCTCGCCGTGCCCTATGACATGCCCATCATCGGCTACAAAAACGGCATCGTAAACACCCTGCGCCTGTGGCAGGCCGAGCCGCTCGAGTCCGGATTCGACTTCGACCGCTTCAACAACTTTCAATATGACGATGCCCTGCGCGAATTAAACCGTGCCGAAGACATCACCCGCGTGCTCTATCCCAACGACATGCAGCGCGCCGGCAAGGTGTTGCGCTTCAAACAGCAATACTTCTTCACCTCCGCCAGCATCCAAGACCTTCTCACCCGCTATAAAGAGAATTTCCCCGAAGACACTAATTTCCGCTCGTTCTCGGCGCTGCATTCCATTCAATTGAACGACACCCATCCCGTCATCGCCATTCCCGAGCTGATGCGCCTTCTCATCGACGAAGAGGAACTTTCCTGGGACGATGCCTATGATGTTGCGACGCATACGTTTGCGTTCACCAACCATACCGTCTTGCAGGAAGCACTGGAAAAATGGAGCCTCGATATTGTCGACGAGGTCTGCCCGCGCTGCCTGGAGCTCATCAAGGAAATCAACCAGAAGATGATTTCCGTGTTCCGTCAACAGGGCATGCCCGAGGAGCAGATCAACACCTACCGCATCATCCACGACAACGTCGTGGAAATGGCCTATTTGGCGGTTTGGTGTGCTGTCGCGGTCAACGGTGTGGCCAAAATCCATACGCAGATTTTGCAAACCGAAACCTTCAAGCAATGGGTTGCCGTCATGCCGGAAAAATTCAGCAATAAGACCAACGGCGTCACACCCCGTCGGTGGCTGCAATATGCCAATCCCGAGCTGTCCGCCTTTATCACGAAAAAGTTGGGCAGCGACGCCTGGCATCACGACCTCACCCTTTTGAAAGGACTGGAACGCTACGCCGACGATCCCGAAACCCTTACGGAGCTCAACGCCATCAAGGCCATCAAAAAGAACCAGCTGGTGGACTACATTGAACGCACCGAAGGCATTACCTTGGATCCCGACTCGATTTTCGACATCCAGATCAAGCGCCTGCATGAGTACAAGCGCCAGCTGTTGAACATTCTGCACATTCTGCACTTGTACAATATGCTCAAGAAAAATCCCGGTCTGGACATGGTGCCGCGCACGTTTATCTTCGGCGCGAAGGCCGCGCCCGGTTATTTCCGTGCCAAAGCCATTATCAAGTTCATCAACGAAGTCGCCCGGATGGTCAACGCCGACCCGGATACGCGCAAAAAACTGCGCGTCGTCTTCGTCCAGAACTACCGCGTCAGCTCCGCCGAAAAGCTCTTTCCGGCGGCGGACATTTCCGAGCAGATTTCCACGGCCGGAAAAGAAGCCTCCGGCACGGGCAACATGAAATTCATGCTCAACGCCACCCCGACCCTCGGCACGTATGACGGCGCCAACATCGAGATTATTGCGGATGCCGGCGAAGAGAACAATTTCCGCTTCGGCGCCACCGTCGAAGAATTGGAAGGCATTGCTTCCTCATATAATCCGCTCGAGTACTACCATACGAAGCCCGAAATTAAGGAAGTGGTGGACTATCTGTTGGATCAGCGCCTGTCGGACCACGGCACCTATATGTTCCTGGATGTCTATAATTCGCTGGTGGCACCCCAACACGGCGAACGCGGGGACGAACACTATCTGCTCTACGATTTTGAAAGCTATGCCGAAGCCCAAAAGCGCGTCGACACCGCCTATCGCGACCGTCTCGGCTGGGCGAAGAAGTGCCTGATGAACCTCGCCAACTGCGGCGAATTCTCATCCGACCGCACCGTGCGCGAATACGTGCGGGATATATGGAAAGTGGACACCATTCAATAGTCGTCAACACCGGCCGCCGCTAAGGCGTCCGAAATGCTCTGCGCGAGCCGACCTGGCCCGTTGCATCGAAAACCGTCACACGAAGTCACACGAAAAGGAGGAAAATATGCTGGTATCGGCCAAAGAAATGCTCATCAAGGCGGCGAAAGAACACTACGCTGTCGCACAGATCAACATTAACAATCTGGAATGGACCAAAGCCGTTCTGGAAACCGCGGAGGAGCTCAAGTCGCCCGTCATCTTAGGCGTCTCTGAAGGCGCCGGAAAATACATGGGAGGCCACACCACCGTCGCCGCCATGGTGCGCGCAATGGATGAGGCCCTGGGCATTACCGTGCCCGTCGCGCTGCACTTGGACCACGGCACCTATGAAGGCGCGAAAAAGTGCATCGAAGCCGGCTACACCTCCGTCATGTTCGACGGCTCTCATTTCCCGCTCGAAGAGAATCTGGAAAAAACCACCGAAATCGTGCGTCTGGCGCATGAACACGGCATCTCCGTCGAAGCCGAAGTCGGCACCATCGGTGGCGAGGAAGACGGTGTGGTCGGCATGGGCGAGATCGCGGATCCCGCAGAATGCAAACGCCTGGCGGATCTCGGCATTGACTTTTTAGCCGCCGGCATCGGCAACATCCACGGCGTCTATCCGGCCAACTGGAAGGGCCTCGACTTTGATGCCCTGCAACACATCAAGGAAGCAACCGGCGATATGCCGCTCGTCTTACACGGCGGTACCGGCATTCCCAAGGATATGATTTTGAAAGCCATTTCGCTCGGCGTCGCCAAAATTAACGTCAACACTGAGTGCCAGCTGTCCTTTGCGAAGGCCACGCGCGAATACATCGAAGCCGGCAAGGACCAACAGGGCAAAGGATTCGACCCGCGCAAGCTGTTAGCCCCCGGTACGGCCGCCATCAAAGAAACGGTCAAAGAAAAGCTGGAGATGTTCGGCTCGGTGGGCAAGGCGGAGTAACGCCCCACAAAGCATGCCGAATCCCAATGCGCGGCAGAAAACAGAGCGTCCCGATAGGGGCGCACGACTCACAGCCTGTGGCATACATGCGGAAGAGGCCAAAAAAGTAAGCTTTTCGTTACTTTTTTGCAACAACTTCACGGAAAACCCACAATTAGCGTTGACGAATGCAGGATGAATTGGTATGATGAGCCTGTAAATCAAGAAGTTTCTATTTTCCGGAGCTTCCACGATTACATGCACAACCATAGCAGCTGATCACAAAGCAGGAAAAAAACAAATTACGGAGGATGACAATGAAAACGAAACGTATTGTAGCATTGGCTCTTGCTGGCGCTCTGGCGTTCGGCGGTGCCCTAGCAACACCGGTTTTGGCGGATGAAGCAGTTCAGGCTGCGACAGTGTCAGACGAAGATCTGGCTACAGCTAAAATCAAAATGGTGTATGACGCTTCGGTCTATAAGGCTGCGGCAGAGAAGAAGGTCAAAGAAGCAGGGCTGGAAGGCAAAAAACTTTCTGACTTAGAGAAAGCTATGACCGATGCTGAGAAAGATAAAAACACTGCAATTGACAATTGGGTGAAGTTGGGCAAAGAAAAAGGTGCAAAGCAAGATGCTGTGAACAATGCGGAAGAAGCATTGAAAGCTCCTAAAAAAGCTTGGGAAGATCTTGCCACGCCGTATGGTTTAGCTGGCCTGACAGCGACCGAAGCGGAAGACATCAAAGCTGCAATTAAGGCCCGAGCGGACGAGATTGAGGCAACTGAGCCGGCTAAAGCTCAAGAATTAAGAAAAGCTGCCGTCATTGATTCGCTCGTTCAAGCAAAACAGAAGTATGATGCAGCAGTAGAGGCTCTTAAGGACGCGAAAGAGAATTTGGCGAATGCAAGTGTGGCTCTTAAGGATTACAAAGAGTACACGGAAGCAAAGAAAGCGTATGATAAAGCCGTTGCTGACTTCAACACCAAGAACGAAGCTGAAGTTGCAAAAGATTTTGTTGACGCGCTGAACGCTTTAAAGCCGACTCTTGATGCAGCTGAAAAAGCAAAAGTTGATGTGGAAGGAAAATCTGCGAAACAGATCATCCTTGCTCTGTTAAGCCAGACCAAAACCACAAAGGGTCTGTTGGCTGCTTTGGGCGAAACACCGGCACCGCAACCGGGCGAAGAGCCGGGCAAACCGGGCGAAGAGCCGGGCAAACCGGGCGAAGAGCCGGGCAAACCGGGCGAAGAGCCGGGCAAACCGGGCGAAGAGCCGGGCAAACCGGGCAAGCCGGCAGAGAAACCGGAAGTAAAGGACAAGGACAATAAGAAAAACAACAAAAAAGCTCCCAAGACCGGCGACATCACCGTATTGGCGTATGCAGGCAGCGCGGTATTGGCTGCGGGCGCATTTGTCGCTTCGAAAAAACGCAAGTAAGTTCGCATAACGTGCTGCTGTTGGTGTGAATGACAGGTTTGTCCTGGACAGACCGAAGGAGGTGTTCCGAAAGGAACACCTCCTTTTTATTGCCATGTAGCAGGAGCGTCGTTGCACAGTGGGCTCGACAGGTGTCTTAGAGAAGCCTACGAAGCACGGAGAACGGCATCCGGGCAGGAAAGGAGCAATAAAAAAGCCCGCCTTATGGGGCGGGCTTTTCTTCGGGCGAGGTGTTTTCGCCGGACGGATTCGGATTCGGGGGTGCCTCGGTTGTGGAGCTCTTGCTGCTTTCGGGCTTGGACTGGCTCTGCGAAGACGACGGTGCCTGCGTATCGCTGCTGGTCTGCGCGGAGGAACTTGAGCTACTCTGTTGCGACGATTGTTCCTGCGAGGAGGAGCTCGATGACGATTGTTCGGACGAAGCGGGCGCCGAGGAGGCGTTCGGAAGAACCGGAATGACCGGCGGCTTGGGCTTCGCCGGAGGCGGCGTCGGCGTCGGTGTATGGGTCTTGCCGCCGCGTGAGGGTGCCGGGACGATGCGGATATCGGGCACGCGGCTCTTTTCCGTGGTTGAGGGTTCTGTGCGCGGCTTCTCGGAAGACTGCGCCACCATGAAGTTGTCCTTTTCCACCTTGCCGTCTGCCAAGATGCGCAACACCAAGGAGTTGTCCGTCATAGTTGCGCCGATGGTGGTGGGTTTTACGAAATGGGGGCTCGTCGGATTGGAGTAGCCGATAATTTCGCGCGCGCCGATTTCGCCGTGTTTGGCCGTGGGGGCAATCTTGACGATCGCTTCGACAGGCTTCTTGACCACGGTCTCGGAGAGCGCTTTGCGCGATACTTCTTTGCCGCCCGACATGCTAACCTCATAGGTGATATTGCTCTGGCCGCGTTCGCCCGGCTGTACGATGCGATATTCGCCCGGCTTTACGGTATCATCCACTTCGGTCACAATGGCGAACTCTTGTTCCATAAGTTCGGTAACCTCTTTGGTCTCCTCGACGCCGGAGCTTTCCTGTCGCGGCGCATCCACAAGCTCAAAGCCGGGATTGCTGCTGCAGGCGGTAAGCACGGCACCGCTGAGCGCCAAGGCGAGGAGTAATCGTTTCTGTTTCATCTGGTCCTCTCTCTCTGTTCGACGCCCTTTCGCGCGTCGTTACGCAAATAGTATACACGATGAAGGCCCCGCGTGCATATCTTCTGCACCCCGCCCGGCCCTTTTCTTGCGCCGCCGGCTCTCCTCGGCGATGAAGCTTTGCAGGCGCACTTCCGGTTCGTCGAAGATGCGGCGCACGAAAAGGGCCGGGAGGGGCGATGCGCGGCTGGCAGAGCGTTGGGTGAGGCGCGGGGTGCGGAGATGAGGCGCGGCGGGCGGAGCTGCTGCGGAGGACGCAGGTGTCTGGAGCGCATGGGTTTCAGTGGAGCGCCGCTGGAACCGCTTTTGGCGGCGCAGTTTCTAAGAGGAAGCCGCCTTCGGCGGCGTTTTCAAATCGCCGGCCGCAGGCCGGCACCTTATTTTGTAGAGGGGAATCGTCAAAAAGGCGAAACACTCTACGCCCGCTTGCAACACTGTAGAGTGGATTGCTGAAAAAAGCGAAACCACTCTACGCTCATTCGTGATCCTGTAGAGTTGAATGGCGGAAAAAAGCAAAACCACTCTACACCTGCTTGCGATCTTGTAGAGTGGATTGCTAAAAAAATCAAAACCACTCTACACCTGCTTGCGATCTTGTAGAGTGGATTGCTAAAAAAGGCGAAACCACTCTACGCCCGCTCGCAACCATGTAGAGTGGATTGCTAAAAAAGGCGAAACCACTCTACACTTGCTTGCACAACGGTAGAGTGGTTTTGCCTTAATTACAAAATAAACATGATTTTTGTGACACGCTGAAAAAAAGAGGAGCGCCGCTTGGACTGCTGTTGGCGGCGCGTTTCTAAGGCGGAGCCGCCTTCGGCGGCGTTTTCAAACCGCCGGCCGCAGGCCGGCTCCTTCTTGGTGGCGTTGGCGGCAAGAAGGGGCCCTTTTTCGCATTTCGCGAATATGGGCTCCTGGGCTTTGGTGATTTTTTGCGATAAAAGGAGCCTTTTATTGCAATTTACGAATATGGGCTCCTGGGCTTCGGCGATTTTTGGCGAAAAAAGGAGCCCTTTTTTACAAATCGCAAATTTAGGCTCCTAATTTTTAGTTTTTTTCTTGCGCACAAGGAGCCCTTTTTTGCAATTCACAGTTTTGGGCCCCCAAAATGCAGATTTCCTAGTGGTAAGCGGGAGCCCTTTTTCGCATTTTCCTCTTTTGGGCTCCTAAAATACGACTTTTACGATCATGGCCGGGAGCCTTTTTCTGCACTTCGCTGTTTTAGGCTCCTCAAAGGCCTCAGTGGAGCGAAGCACGAGCTTACACCCCGCGCTATGCACCACGCTTATACTTCGCCCTCCGCCGCGCCCGCGCCCCACCCATCCCGAATTCCCGGCGGCGCGCGCACCGAATCCGTTATAATGGGAGAGAACAGGAAGGAAGGGACGATGACGAAGAAAAAACATCCGGTGGTGGACGTGCGAATTGAAGAGCTGGCGTATCCCGATCGTGCGAGCGGCGTGGTGCTGTCGACGATTGCGCATGATCCGGTGGGCGAGATGCTGGAGTTGCCCGTGGATCACAGCAAACGCGAGGCGGTCGCGCCCATGCGCATGAAGGGCGGGCTGCCGGGCCAGGTTTGGCGTTGCCGCGTGAAGCGTTCGCATGCCGGGGTGCGCGAGGTGATGCCATTGCAGCTGCTGGCGCCGTCGCCCATGGAACATCGTCCGACTTGCCCACAGGCAGGCATCTGCGGAGGTTGCAATTACCAGACGATCAGCGTGGAATCGGAGCTGCTGCTTAAAAGCCGGCAGCTGCGGGAGCTGTATGCGCCGCTGGGGCTTTCTTCCGCGATTTCGCTTTATCGCAGTCCGCTCTTGGAGGGCTATCGCAGCAAGATGGAGTATACCTTCGGCGACAGCACGCCTGGCGGGCCGCTGACGTTGGGGCTGCATCGTCCGGGCCATTTTTATGACATTTTGCCGACGCCGCTGTGCAATATCGTCCCGGAGGATTTTAATTCGTTGCGCAAGGCAGTGGAGCGTTTTTGCCGGGAGCGCGAATGGACATTCTATCATCGTGCGAAGAAGAGCGGCTATTTGCGCCATCTCGTGTTGCGTGCGGCGCTTACGACGGGGGAGCTCATGGTCAATCTTGTGACGACCTCGGAGCGCACCTGGACGGCACTCGATACGACGGAATTTCTGCGCCTTCTGCACAGCCTTTCCCTTTCGATGCGCCTCGTGAGCGTCTTCCACACGACCAATGACAGCGTTGCGGACGTGGTGCAGGCGGATGCTCTCGATCTTTTGGAAGGACGTTCTTACCTGGAAGAGCGCCTTTTTGACCTCTCGTTTCACGTGGGGCCGTTTTCTTTCTTCCAGCCCAACGTCATGGGTGCCAAGAACCTCTATTCCAAGGCACTTGACCTTGCCGGCGACCTGCGCGGCAAGACCGTCTACGATCTCTATTCCGGCACGGGAACCCTCGCGCAAATTGCCGCGTCGCGCGCCCAGCGCGTCATCGGCGTGGAGATCGTGGAGGAAGCCGTCGAGAAAGCCCGTGAAGCCTGTCAACGCAACGGTCTTGCGAATGTACGCTTCGTTGCATCCGACGTCCTTGCCGAGCTGACCCGTCTCGCCGACATCGGCGATCGTCCCGACGTTGTCCTTCTCGATCCGCCTCGCCAGGGTATTCATCCCAAGGCTGTCGCCCACCTCATCGCTGCTGCCCCCGAGCGCATCGTATACATCTCCTGCAATCCCACCACACAGGTTCACGACCTGTCTCTCTTTACTGCCGGTGGCTACCGCGTCGAGCAAGTGGTTGCCTTCGACCAGTTTCCGCGGACGAAGCATGTTGAGACGGTCTGTTTGATGTCAAGAAAGGACTAAAAGGCTTGAAAGCCTTGATTTTACGGCGTTTTAGCGGTTTTACCGTTTGTTCGGAAAGCGTCTGATTGGATGCAAAAGTAGTCGAAATAACCATAAAATGAAAAATCCCGCTCCGATTCAGAGGCGGGATTTTTTAGTGAAAAGAACTGTTTTGGTCATACAATTGTAAAGGCAAGTTGAATGTTGGTATATTCCTGCCTTGCGAGTCGGCAAGATGGTTGTCAGATGATTTTTGGTCAGACAGTTGGAACGGTAAGATGGTTGTCAAAACACTACTGCTTGATAGATACAGATACACCAGACGTAAACCGGACATCAATTTTTTTGTCATGAATCGTGATGGTATCCACCATTCTGCGCACCAGCGCATCATCCAGAGTTGTGAGTATACCGGTCTGCGCTTGTAAAAAGTCGCGCATCGCTTGGATGCGCAGGATCTGATTGTCCGTCTTTGCCTGAGCAAGCTCGGCTTGCATTTTTTCTTCTTTCACTGCATCAATCTCATTTGCAACGTCTTCATAGGGTTCTCGATTCGAAATGCGATCCATGAGCATTTGCTGTAGATCCTCCAGTCTTTGCTCTATCGATTTCATGTCTACTGAGGACTCGTGGTCAATCACGTGAGTAATCCGATCCTCCAGTTCAGCAAAAAAGCACCCCTTATCTTTAATGCAACGGTTAATAGCAGAAAGCACAATGCCTTTCAAAAACTCCTCCTCCACCGTTCTCGCATGGCAGGAGTTGTTTCCGGGAGTAAGCCTGCTCATGCAGCGCCAGACGATGGATTTGCATCCCCGGTTGTTCCAGTGAATCCGGCGGTAATACTCGCCGCACTCACCACAGATAACAAGCCCGGACAGACAGTGGTTAGACGAGTAGGCTTTTCGTTTGCCATCCGCTCGCTTAGAAAGGTTGCGTCTTCTTACCAGCTCGTCTTGAGCCAGCAGGAAGATCTCCTTTGGAATGATAGCTTCGTGGTCATTTTCCACATAGTACTGTGGCATGTGTCCTTCATTTCTTACGCGCTTCTTGGTCAGAAAATCAACGGTGTAGGTTTTTTGCAAAAGGGCATCACCGATATATTTTTCGTTGGTGAGAATTTGGCGAATATTGCTGGGAGTCCATTTGGTGTGTCCGGCTCCGTTTCTTATGCCATCCGCCTCAAGTCCTGCAGCGATTTTGTTCATGGAAAGCCCCTCAAGATACTCTCGATAGATGCGTTTTACCGTTTTTGCCTGTTCAGAATTGATCACGAGGTGACCATCCGCATCTTTGTCATAGCCTAAAAACCATTTGGCGTTGACCTGCACTTTTCCCTGCTGGTAGCGGTACTGGATGCCGAGTTTCACATTCTGAGACAGACTCTGGCTTTCCTGTTGAGCAAGGGAGGCCATGATGGTGATCAACACTTCGCCTTTGGCATCCATCGTGTTGATGTTTTCCTTTTCAAAGAAAACTGGGATGTTGATTTCTTTGAGCTTTCGGATGTATTTCAGGCAATCAAGCGTATTTCGAGCAAAACGCGAGATGGACTTGGTAATAATTATGTCGATCTCGCCTGCCTCGCAGGCATCAATCATACGATTGAATTCTTCGCGCTTTTTGGTGTTGGTGCCAGAAATGCCATCATCGGCAAAAATGCCCGCCAGCTCCCAGCCTTTTTGTGCCTGAATGTATTCCGTGTAGTGCGCAACCTGTGCTTCATAGCTTGTTGCCTGTTCGTCGGAATCTGTAGAAACGCGACAGTAAGCAGCTACCCGAAGAGTGGGGCTTGGCGTTTCCGTCTTTGTGTTTCCCTGCTTCTTTCGGGCGGGAATCATGGTGATGTTCTTATTCATCTTCAACCTCTCGGATCTGGTTATAGACATATACGGCTTGCTCGAGTGCCGACCGGTCGCCGCAGTCAATCTCATCCATATAAAATCGGGTTTTTACGTAAAAGGTAGGTCTTCGTTTATGGCGAAGCTTCTCCTTGCCCAGATTCTTTGCACGAGAAAGACGCAGCTCATGCGCCTGTTTCAGCCATTCTTCGCTGATGAGTGCGGGGTACCCCTCACTTCCTGCATAAATCGGGTTTTCCAGCAGGCGACGGATGACACTGTGCGTAAAGGTAATACCGACCGACTGCGCAGAAGCCTTCAGACTCATGCCGCTTAAGTAGTTTTCAAATAAGGACTTCAGAGCACACGCTTCCTCTTCGTGAATAGCGATTTTGCCATCTTTCATGCGGTATCCATAAGGAATTGTTCTCATTATTTAGGCCAGCCTTTCCGGAAGACGGAGTCCGCATTTCAGGATGAAGCAGACCTCGGTTCGACTGACAACCTCTACGGCATCGACGAACCTTTTGAATTCTTCCTCGCAAAAGCGTTCCGAAACTTTTCTCCCTTTTACATAGTGGCAGAGCGCTTCGAGGTTTATTACGGTATCGTCTTTCCCGGCTTCCTGAATTTTGAGCTGTTCGCGCTCTTTTTTTCTTTCTTCAATTCGCGTGACAAGTTTGTTTTTCTCCTTGAGGAAATGCGGACGGTCGAGGTATCCCGAAGCGCTTAAGCGTGTCAGCACATCCAGCTTGTCTGAATCCTCACGAATGGCTTCGTTTGCTACTTTGAGTTCTTTTACATATGTCTTTGGCTTCTGACCTTGCATCTCGCTTAATAGAGGTTCCAGTATGGCTTCGCGGGCAAAGGTCAATTTGTTCATCATGCTTGCAAAGGCGCAGAGAATGCCATCTTCATACACAGCCTTGAAAGGGCAATTCTTCTTGCTGTGCAGATGCGTACTGCATGCATACATCTTGTAACTGCCGCTTTGCGTATAGCGAGTGATGCGCTTCATGACCGAACCGCATGCTTTACATCTCACCTTCCCGGAGAGCACCGTTCGATTGAGATACTTGGGGCTCTCCTGAATGATCCCTTTATTCTCACGCTTGAGCTCGATCAGTTCGTTAACCGCGTCATATGTTTTTCTGTCGATGATCGCCTTATGATGGTCTCTCACGAGGTATGCATTTTTCTCACCGTTGTTTTTATGACGCTTGAAGGCATCATCGGTATAGGTCTTCTGAAAAAGGCAATCGCCGGTATATTTTTCATTTTTCAAGATGGCAAGGATACTTCCGCTGCTCCAAAGTCCTCCGTGGGCAGAAGGGATGTTTTGATCATTGAGAATTCTTGCGATTGAATATCCGCCATATCCTGCCAGCGCAAGTTGAAAGATCTCTCGCACGATCACAGCCTGATTTTCCACGATTGCCATCACACCATCGTCGTTTCGATAACCGAAAGGCGGGCAGGTGATGATGAATGTCCCGCTTTGGAAGCGTTGCTCAATGGACCAGCGCACATTGGCAGATTGGGAAGCGGACTCATCCTGCGCCATCGAACTTAGGATGGATAAAAAAAGCTCGCTCTCCATTTCACTGGTATTGATATTTTCCTTCTCAAAGTATACGGGGATCTTTAGTTCCAGAAGCTTTCTGACCATGCGCAAGCAATCTGCTGTATTTCTGGAAAAACGACTGATGGATTTGGTTAGCACAAGGTCGATTTTTCCGAGGCGGCAGTCACGCAGCATGCGTCTGAGTTCAGGTCTTGCTTTGCTCTTGGCAGCGCTGACGCCCCTTTCATAATAGATATCGTGCAAAGTCCATCCGTCTCGAGTGCAAATATAGGAAGCATAGTGTTTACGCTGCGCTTCCAGACTTTCAAGCTGCGCGTCCGATTCGGTGGAGACACGGCAATAGACGGCGATGCGCATCTGTTTTTGCTGCTTCCGTTGTGTTGCCACACCATCGATTCTCGTTACTTTCTTCAATGCTTTCACCTCCGCTCTCCTATATAGACGCTCTAAACCAGACACATAGCAAGTTGTTTATTCCATCAGCTGGTAGAGAAATGGCCGATATACACTACGATTTTGTCTGTGCAGTATTTGCGCTTCGCATTCCGCAAGAATCCCTTGCGCATAGAGTTCGTCAACATAAGCCTCGGCAAGCCGGTAATAAACGTCGCGCATCAGATCTTCCTGCACCGGAAGAGGCTGTTTATTATTTATATCGTTTGTCATCGTTGCCCTCCTTATCTCGAGGGCAGATCCGTTTCACCCTCTCCTTTCCACTGGAGATGGCGAGAGGTTTTGAGCGGATTTCCTGTCTTCAAAAGGTGCTGGAGGTGAGAGGAGCGTTTTGACGAAACAAGGGAAAAAAAATAAGCCTGCCGCTGATGAGAACCATCAGCAGCAGGCGTTTTGTTTACACAGGTTCACAGGAGTTCGTTTACACGCTTTTGCACGGCATCATAATTGTAGCCGGCCTTCGTCAAGCGATTCTTTCGCTCGTTGCCGTTGCCCCAGTCGCCATGAATCACCTCACGGGCAAGGGTGTTGATGGACTTTTTCGGCTTGACGGAAAGACGCTCGTTGACCTTTTTCTGTACTGCATCGTAGGAATAACCGGAAGCCGTCAGGCGGCGCTTGCGCTCCTCGCCGTTTCCCCAGAGGCCTTTTATCACCTCGTCAGCCAACGTCTCTACAGTTTTCTTTTCCGGAGCCGGTGCGGGTTTTGCAGTGGGTGCAGTGCTTCCTTTGGCATAGCCATTAAATCCGCCGCCACGGATGAGGGAGGGATAGTCGATGTAAGAAATGTCCAAGTCCACATTGCCGGCAATGCCAGATACGCTGCCCTTGCTGGAGTACTGCCAAAGGCCGCTTTCGCCTTCAAAGCTGTTCGTGTTTGCCCACTGGGCGCACCAGAAGGCATAGCGCTTGCGGATGGATTTCGAGAGAATGTTTCTCGCGACCGAGGCACTCGTGTAGAAACCGGCAAAGTAACCGCCCGCTTCCATTTCATTGCAGAAGGCTTGGATGAGGCTGTCACAGAAAGCCTGCCCTCGAGAAAGCTGAGACGATTCTTCCAGATCAAAAAAGATCGGATAGTCAAACTGCTTTCCGGCGATGATCTGCTTACATACTTTCGCTTCTGACCTTGCGTTATCTGCGCTTCGGGCATACGAATACCAGTAAGCCCCAACATGAAGGCCAGCGGCTTTTGCCCGGGCGTAGTTCTGTTCAAAGGTGCGGTCCTTCTGGGAAGTATCCCAACCATAGCCGGCACGGATGATGACAAAATCAATTCCGTCCGCTTTTACCTTGTTGAAATCAATCGAGCCGTTCCATTTGGAGACGTCAATCCCTTTACTCATGTGTTTCCTCCTTTTCTGCGCGCTCATGGAGCTGTGCGAGCACGACTTTCAGCTTTTTCGGGACAGGCAGTCCCAGATGCGTGGCATTTTCGACAAGGGACAGGCCCTCATTGGAGAGATAGAAGAAGATGACGGCCGTGCGCAGAACCGAGCCAGTACCGATGACCTGAGCATCAATCATGTGTCCGATGCCTACGAGCAGAAAGATCAAGACCTTTCTTGCGATGCCTTTGAAGCCGACCGCACTCGAGAGCTTCTTGTCTGCTACTGCGCACATGATGCCGGTGATGTAGTCGGTGATGACAAAGGCGATGAGTGCATAAAGCAAACCGTCAAATCCTCCAAGATAAAATCCCAGCCATCCGCCGATTCCGGTGAAGATGAGCTGGATACTGTTCCAGAACTCTTTCATCGCGTTCCTCCTAATACGTAATACGTAGAAAGCCACTCCGGCATCTCCGGAATGGCTCCTGTTTCGGTGGCATCCAGCCAGGCCAGATACCACGCATTTAGTTCCTTTTTCTGTTGTTCTGTAAGTCTGTCGTACCAAGGCGTGCCCCGGTTGATGACGGGAAAGCACTCCTTGCATCGACGTTCACGAATCGCATCCTTCGCTGCATTTTTCGATTTAGCAACCAGACGTTTTTTGTCCAAGACAAGGTCACCGTCCCGGATTCGGTAGCATTGGTAATGGAGAGCAAAGTCTTCTATGTCCTCTGGCTCTGCGCATTCCGCTCCTCCGACCAGCATTCCGTCCAAGGCGAAGCTCGTAATAAAACCTTGTTCATCAGTTAGAATCTGCATGATTTCCTCCTTAATTCACCCCAAACACTCGGATAATCTGCCCATTGGAACTTCTGTCGTAGTAAGCAAGTGTCACGGTCGTGCCTGAGTAGTAAAGCTTGAAAGCGTAGTAATTGCTCTCGTCCGCAATCTGGTAGTTGGTGGCTGTCGTAGTGAGCTGGGCGGAAGGCACGACCAGTGCGCACCTCGAAGAAGCAGTGCTGGGCTGGCCGATAATGACGAAAAAGTTGTAGCTCTTCGAAAAGGTCGTGCTACCCGTCGTGATTGCGCCGCTGTAGAGGGAGGTTGCGGTAATCCCGAGATTCGACCGGGCGGCAGAGGCATAGGATGCGCCGGTACCACCGGAGGAGACGGCCAAGGGACTGGTGAGCGAAATGGAAGGCCAGGAGTTCCGGTCGTAGGCGGCTTTTACAGCCGAAGAGGTCGCTGCTGTGGAAGTGCTGGTCGAGCTGGTGCTGGTGGAGAGTTTCGTTATGCCAAAATAGCTGGTATCGGCCAAGGGCGTGGTCAAGGCCACCCAGAAAATTCCGTCATAGATCAGAATTACCGTCTGCTCGGGTCGCCAGTAGTTGGTACCGACAGCCGTTCTTCCCACATTGACGATGTACTTAAGTCCGGTGCCGTTAACGTTGATTCTGGGAAAGGTGGCCGTATTGTTGTGCATGAATTTCATCAAGACCACAGCGCCAGTGTTCAGCGTTTGAAAATCCGGACACTCGCCGGTTTTCTCCACCACATCGGCTGCATCATTGCAAACGCCAAAGGGCAATCCGCCGCTCAGCGATGCGATATACGCTGGTAAAAGCAGCCCGTAAACCTTCACGCTCCAGTCCGGTGCGACCTCGAAGCATTTCTCGATTTCCGATACCTTGCCGATGGCCAGCCCGTTTCCGCCGTTCTTGAAATCCATCACAACGGCTGCGGTGGAAATGGAATCGGTAATGGAGATGCTGGTAAAGGCATCGGTTAGGGTGTATTTCACCTCATACGTATTTTCCGGCGAAATCGAGCCGCTTCCGAAAGTGAAGGGTGTGTTGCTCGTAAAGGTTGTAGCGGCATCTGTCCAGGTCGCGTCGGATTCTTTTTTGTACGATACCGAGGTGGTGATGGTATTCTTTCCTCCGACAGAAGCAAAGTAAAACTCCAGAAGGGCTCGGACATAAGTGCCATCCCCCTTTGGCGTGCCTGTGCTGTCGGCACGCTCGGACTGCGCACTTAAAAAGCGTGGCGAGTAGTACGGCAAAACGGAGATGCTTACGGTTTTGGCATCGGAGGTGCGTCCTCTGGAATCGGTGACCTTGGCGGTAAAAGTGGTGGTGCCATAGTCATTTAAAAAACCTGTCGTAAGTGAAGAGGACGATCCGGAAAAGCCTCCACCCGTGATGCTGTAGGAGCGAATCGTCGAGCCGTAGCTTCCGGTGGCACCCGATATGGCCAGCGTCGCCTTGGATTTGTACTGCACATACACGCCCCAAGTGGAAGGCACGGTCCCGTCGATATGGCTGGCCGTCAGACTGCCGATGGTCGGCTTTATCGTAGAAGGCACATAAAGCGTGATGGTTGTTGCCTTGGAGCCGATGTATGTTCCGCCATTATAGGTATAGCAAGTGATGGTGCATGTCCCCGAGGTGCTATTTGGAATCTGCGAGGCAAGGCTTAACGGCGGTGTCCAGGACAATGAGGTACCGGTGGTTTTTATGGCAATGGCGCTGGAAACACTGCCAAACCGGTAAGCCAGCGTATGTGTGAAGGACGATACTGCCCGAGAGATCTTGATGGTGGTTGCCGTCCCCATCGAGATGGATGAGGCAGACACAGACGAGGCACGCGGAATCGAGTCCAGCGTGATGGAGGCATTTGCCGTAATCGTACTGTAATAGGTGCCGCTAATCGTCGCTTCAATGTGAAAGACCGCAGAGATGTTGAGCGTCTTTGATCCGTCACTGTTGTGATTGACCGTCTTGGTAACGGAGCCTAAGGTGTGACTTCCTGTGGTATCGACCGCAGGAGAGGAAAAGGCCTGCGACTGACCATCAATCGTGCAGGTGTTATTGGTGCGCCCACTGATGTAAAGGGTCCAGTCGTTCACGAGCACCATCGTGGCCGTGATGGTCGAGTGGTTGTTGGTGATGTCTTTGGTTTGCTTCCAGTCGACGCGCAGCACATAGTGACCGCCGTGAATGGAACCGGAAAAACTGCCGGAAGATGCCATGGGCTGCTCCTTTCTTAATTGGAAGAGGCCCTCCAGACAACGGAGAGGTTGCCGGTCGGGCGCGGAATGAAGTCAAACCAGCCGCGTCCCTCGGTGCCAAGGGAAAGCCGGTAGCGAATTTCGGCGTTGGTGATGACGAGCGATTGATTGGAAATGTAAGCAATGACCTGTCCGTTCTCCTTGAAGGCCAGCTGTTCATTGGAAAGCTCTGCGGTGAAGGCATTGCCGATTTTCCCGAGCTCAATGAGCGCCCCGCGAAAGCGGATATATTCTTCTAACAGCTGCTGGTTGGCGATGACGTTTCCTCGGATTTCATCCGTTTTCGCATGAAAATCCAGCCGGAGCTCGGTGCTCGTCTGCGTGATGCTACTGGAAAAGTCCTGCCGCAATGTCTCGAGGTCTGATTTGGAGACGTACTCCTCACGCACGGCGCTGTTGATCTGTTCGGCAGTTTTCGTGATTTCCGAGTAAAACTGCTGAACGTTGACCTCAAGAGAGGATGCGGCATCTTTGGCCTGCGTTGCTTCGGCAAGCGCTGTGTCGGCTTTGCTTACAGCCGAATTGATCTCTTCGGTCTTTCCCTCGATGTCGACGGAAAGCGCTTCGAGGTTCTTGGACTGCTCTGTGGCAGCCTTGGAAAGGGTGATGTTTCTCGCGCCGATCGTGATGGTGTTGCTTGCCGGATGGAGGTAATCTCGCGTCCTCGCAAGACAAAGGTATCTACCGTCAATGCCGTGGGGCTTGGAGAGACAGCGGATGTATTCTCCGGCATGCATCTCCGAAAGCGTAGAACCGGTATCTGACTCATCCACAATGGAAAGTTCCATGCTGGTGATGCCGTCTTTGAGTTCCGGAAGCCTTGCCTGGGCCTTTCGGAGGAGGTTCTCGGGAAGTGTGACATCGTCCCAGATTTCCGTCGTCCAGATCTTTCCAATCTCCGCTGTAGTGTCAGCGTCCTCTACATAATTCAGTCCTCCGTTGACTGAGGTGATGTCCACGCGGCGTTCGGTTTCGTTGCCTTCGCTGTCGGTTTCGGTGGACTTTGCGCCAAGCGGAATTAGCATAGAAACACGCTTCGTGTGATCGCGGTTGATCTTCACATCCAGCAGGTTCTTGCCGTATTCCACGGTTTGAAGCGAGGCGGCAGTAAAGTCGGCAAGATAGTCCAGCTGCTTTTTGCCGTCTGCTGTGTAGCTCACTTTGAGATAGCCGCCGTGGGTGTCGAGGAGTTTTTCTTTGATGGCATCGAGCGTCACCGAATAGTCGCCGTTTTCATAAGCGACGTAATCATTGGTATCGGACACGGTCACCGTTCCCAGCACAAACTGCTTCTTTTCTTCCACGGCGCTGTTGTGGGAAGAAAGAAAAAGTTCCAGAAGACCTCGAAGAGGGCCCTGATAGTGATAAGGTGGCTGAAGACTGTCTTTGAGAAAAGCCAGCGCCGACTCGCAGATCCAGGTGTGCGTATTGTAAAAATCCGTCCCATCATCCAGCACCCGGCCTTCAAAGACAATCTGATCGCCTTTCTTGCAGATAATGGTCGATGCCAACGGGTGAATCTTTGTGATATAGGGATGCGTGAACGGCGCGGAGAGAATGAAACGGTCGATGCTCTGAGCATCCTCCTCGATTTTGGCTTCTGTGACGGCCAGTTCGCTTAAGTCCGGGTGGTAGAAAAGGGCGCCGTCGACATAGACTGTAAACTGACTCATAGGCGGCCCTCCAGGTAGGTAAAGGTGATGGTGCCGGTGCCGGTCACAGTGATGGTGTTGTCTCCCGGTGCCAGCTCCAGTTCCGGCACGGTCCAAGTGCCGGCGCTTAGGGTTTTGGTGAAGGCATCAGCACCCGCTTGCCAGGCAAGCGTCGTTTCTGCTGTCGTGGTGATGGACGGCACGACGGGCATAAAGTCATTGGCGAGCGAAAGCGTGCCGCTCCCCGTCAGCGATTTTGTCGTTTCCTGCACGTGGTAGAGGTAGGCATCCGCATCTTTGGAAGAAAAGACGAGGACGCCTTTGTAGGTTCTCGGATCATAGCTGGACTCGGCTTCGAGCGTGCCAATGGCATAGACCGACTTGTCTTCCGTACGGACGACCTTCACCAGTTGTCCGGCAAAGCGGTTCACGGTCGTGCTGACTAAAGCATCAAACCGCGCGCGAGTGCCGAACATAGAAAGGGTGATGGTAAAGCTTCGGGGCTGGAAACTGACTTTGCCTAACGCCTGGGTAAAACGCAGTGGCGCGCTCCGTCCTGGAACGACGAGGGACTCGGACTGCGAGAGCGGGACCGGAAAGTCCACGGATTCCCGAAGCCAGCCCATGGAAAAGAGGGATACGTCATTGAAAAATACATCGGGCTTCATAGGCTTAACCTCGCATTCCATTTCTGCTCCTGACCGAGCTTCTGATCAATGACCGGGAGAAGTTTTCCGATGAGCGTGCCGTCTTCGAGATAAATGCCTTTCGAGCTATTGGCGGCGATGACGGCGAGATATTTCTCCATGCCCTCGGTATTAAGCTGGCTTGTCAGGATGCTTCTGAGTTCCTTGTAAAATCCCTCAAGCGGCAAAATGGCCTCAGGGCCTGCCTCGCCGCCGGCCATGAGAGAAGATCCATTCATCCCAAAGAGCGTGGGATTTGTCATAATGCCGCCTTCTTTGTACCAGCTGATGGAAAGGTGCGGCACGCGCGGCGGGATGATGGAAAAGCCGCCCGAGATGGAAAAATGCGGGAGCTTAATTTTGGGCAGGCTGATATGAAGCCCCGAGAAGAAACCCTTGATGGAGTCTACGATCCCCTTGATGGTGTTCTTCGCCGCCTCAATCGGCGAGGTAATGGCCGTCTTGATGCCGTTCCAAACGCTGGTCGCAGTGGACTTGATTCCATTAAAGACGGAGGTCACAGTCGATTTGATTCCATTAAATACGGTGCTGATGCCCGATTTGATGCCGTTGATCACTCCCGTAATCGTTGATTTAATCCCGTTCCAGATGCCGGATGCCGTGCTTTTGATCCCGTTAAAGACGCTGCTTACTGTCCCGGAAATGGAAGACAGTGCCCCGGATACGGTGCCGGTTATGGCGTTCCAGATGCTGGAGAAAAAGCCTGCAATGCCGTTCCAGATGCCTTCAAAGAAGCTCTTGATCCCGTTCCAGACCGATTCCCAGGTGGCACCGAACCATCCAAGGGCCGTGTTGGCCACACCCTGAATGGTTGCCCAAACGCTTGAGAAAATGCCGGAAATGGCTGTCCAGACGCCGCTGAATACTTCCTTGATGCCGTTCCAGACGGTGCTCCAGTTTCCGGTAAAGAGGCCGGTGAAGATGTCAAAGATGCCCGTCAGGACATGGAGCGCTCCCTGCAAAATGGCGGCAATCGCCTGAAAAGCGCCTTGAAAGACGGGCGCTAATAGCTGGGTGAAGCCGTTCCAGATGGCCGAAATGAGCTGACCAAAGGAGGTGAAATTCAGCCCCAGCGCGTTTAACCTTTCGATGATGCCGCTTTCAAAGGCGCTAAAGGCTTCTTTAATCTGATTCCATGTCGAAAGAATGGAGGTACGAAAACTCTCGGAGGTGTTCCATAGATGCAGAAAGGCTGCTACCAGCGTACCAATCCCGGCCACAATGAGCGTGATGGGATTGGCGAGAAGTGTGGCATTGAGAGACGACATCACGGTTTTTACTTTGGTGATAGCTCCAGCAATGGCCGGCATATTCGTCATAATGGTTCCGACGGCAGAAACCACTTTACCGATGACGATGAGCAAAGGTCCCAGTGCCGCCGCAATAAGGGCAATCGTCACAAGCGTCTGCTGGGCGGGCGCCGGGATGCTTTGCCAGACTTCCGAGAAACGTTTGAGTCCTTCTGAGATGCGTTCAAGAACAGGAGCAAGCACCGCAGCCAGGCTGTTTCCGATATCTGCACCCGTTTCTTTCAGCGAGTTCATGGTCATCTGAAACTGATCGATGGGATCCAAGGTTTCGCTGAAGGTGTTCTCGACGCTTCCCGAAAAATCTCCGAGCATGCCGGAGAGGTCTTCCAGATTGAGCTTTCCTGTCTGCACGGCATTGTAGATGGCCGCTCCTGCGCGGGTGCCAAAGAGGTCATAGGCCGCCTGCAGTTTCTCGGTTTCCGACTGGTTGGAGTTCATCGTATCGGAGAAACCTTGCAGGGCTTCATCTAAGGACTTCCCGTCTGCCGCGGCACTCTTCATGGCGGTCTTTAAGCCCATCATGGCGGCCGAGGTATCCAGACCGGACATTTCCACCATGCCCATAAAACCTGCCGCTTCTTCGGCGGAGAGGCCCATCTCCTTAAACTGGGCGGCATTGGAGGAGAGTCCTCGTGCCAGCTGATCCATGGAGATGCCCGTGGACTGTCCGGTCGCATTTAAAGCATCCAAGAGGCTTCCTGCATCGTCCGTGCTTTGCCCGAAGGCATTGAGAACAGAGGAGACATTATCCACAGAAGTCGAAACGTCCGTGTTGTTGAGCTGGGCAAACTTGATGAACTTGCCGGATAGCTCGGAGAGCGCCTGTCCGGTGAGACCAAATCTTGTATTCACCTCACCTACAGCGGCACCGGCTGTGGCAAAGTCTGTGGGGATTTCCGTGGCAAGGCTTTTGACGATGCTCTGCATCTCTTCAAGCGCCTGCCCGGAAGCGCCGGTTTTCTGCGTCACGATATCCAAGCCTTCATCCACTTCAGAAAAGGCCGCAAGGGAAGCCGCGCCAATAGCGGCGATGGGTGCCGTCACGCCTTTGGTGAGGGATTCCCCGACACCGGAGATTTTTCCGCCCACATCCTGCAGTTTGCTTCCCGTCTCTTTGAGCGTCGCGGAGACAGCGGAGTCCGAGCTTTTGACTTGCTCTTCGAATTTCTCCAGCTCCTGCTCCGTTGCAATGATTTCTCGTTGCCAGGCATCGTATTGCTGCTGTGTGAGCGTGCCGTTTTTCAGCCCCGCATCCATCTGCTCTTGCACGGATTTGAGCTGTTCGAGCTTATCTTTTGTTTCGCCCACGGCATCTTTGAGGAGTTTTTGTTTTTGCGCCAGAAGTATGGTGTTTGCCGGATCCAGCTTTAAGAGGCGGTTTACGTCTTTGAGCTGGGACTGGGTGTTTCGGATCTCTTTGTTCACGCCTGAGAGGGCTTTGGAAAGGCCGGTGGTATCGCCGCCGATTTCCACAGTTATGCCTTTGATTCTGTCGGCCACGATGCGACCTCCTTTCTTTTCATGCAAGAAAAAGGCACCTGCTTGGAATCAGCAGATGCCTTCTAAAACCGGTCGAAATCCTCCTGCGTGGCGATGCGCCGGTATTTCACCTGATCGTTTGCTTTTTCTGTCCACATATCCAGAAGCAGGCCAATGGAGATGAGGTCTAAATCGCGCACCGAAAGGCCAATCTCCAGTGCCCTGAGCATGAGAAGCGGCGTGGTCATTTCCCGCTCACTTCTCATTTGCCTTTTTTTGACGCCACCTCGGTTTTCATGTTTGCTCCCCAAAGGGAGAGGATTTCCGGCAACACCTCATAGATGGAAAACATCTCAAAGCCGTCCAGCCACTCCTCGATGGAAGAAGGGATAGATGCATCCGCATGAAGTGCCATGATGTAGGCCACGTTTTCGAAGATCTCCAAATCCTCAATGGGAAATCCACCGTCCTCCGCTTTTTTGCCGGAGTAGCTTTTTTCGAGTTTTGCCAGATCCTTAAAGATGTCCCGTCCGAACTTAGCACGGTACAGGCGCGGGATCGCGGCAGAGGACTTGAAGGTTACTTCTTTTCCGGAGACGAGGATGGTTTTCTCAATCATGCGGCGCCTCCAGCCGTTTTATTGGTCGGGACGTATACGGCCGTATACCATCCGTCATAGGTTGTAGCGTCCGTTCCGTCACCGGTCTTGGCCTTCACCAACCCGTCGCTTCTGGGGTCTGCCGTAAGCGACAGCGTCTCGGTGCCCGGCTCAATGGTGTCCTCCTTGGTTTCTGATGCGATGGAAGGACGCGAGGCTGTGCAGTTGTAGAGTACGTGGCGAATAGCCTTGATGTCCCCGTCGAATTCAAAGAGCAGTGCAAACTTGACGGATTCTGCAGCATTGGAGTTTTCCACGAGCACGCCCTTGGCATCGAGCGTTTCCTGCAAAATCTCGGTGCGAAACCACTCCGGGATGAGGGCAATCTCCAAATCGCCCGAGTAACCGTTGTTGGTCACGGTGCGGAAGTAGACAATCCCGTCTGCATAAAATGGCGAAGATTCTCCCTCGGCATCCAGCGAGAGCGACACCGCGCCCGGGATGCGTTTGGGCGTGGCATAGGCAAAAGTGGAAGCGCCATCTTCTGCAATCGTCTCGGTGAGCTTGGCCGCATAGACGTTTTTGATGTTGTATTTGACTTTATTCTGTTCAGGCATCTTTATTCTCCTTTCAGTTCAAAGGAATAGAGCACCTCATAAAGGTGCTCAGAGTCGATATAGACTTCGGTTTTATCAAAGAAAAGACCGTGGGCACTGAGTACAGCTTCCACGGCTTTTTCGACTTCCGGCTCTTTCTTGTCGGTGTAAAGTTCCACATTCCAGACGGAGACCAGGAAATAGACTAACCCATCTGCCGCGAAGTTGCGACTTTCCGGCGTTAGAAAGATGAGAAAGGGTGGATCCGGCGCGTGGCCTTCCTCGAAGTGATCGTAAGCGAAGGGAACGTGCATCTCAGAAAGCATCTGCATGATTTCATCCATCGGAGAGGCTCCTTTCCAGTTCGCTCATCAGCTTTTCTTCGCCGTTTGCTTCTGCTGGAGCAATATGCGGAAAAGCGCGCGTGCGTCCTCCGCCGCGTTTGGCGTGTCCTTTTTCCAAGAGGTGTGCCAGCTGGTAGCGGTCCTTGGAATGGACGGTCACCTCCAGCAGGTTGGCATTTTCTCTGGTCGTCTTAGTCGCCCAGCTTTTCTTGTAGTCGCCAGAATCTTGTGGCGCGTTCTGCTGAATCTCTTTCTTGACCGAGGTGGCTGTGCTTTTGACGATTCTTTTCATATCATCGCTCGCAACTTTCGCATACTCCTGGAGCGCCAGATGAATCTGATCGGCCATCTCATCGACGGATACTTTTCTTGTCATGGGCGCTCCTTTCTGCAGAAAAACTTGAGGGCCTTTTTCTTGAAACTTAAATGGTCGATGCGGTTGATGTCATAAGGCTCGCCAAGAAACAGGATCCGAAATCCCGTCATGGTGATTTCCGAAGCTTTCCTGCACCAGCGAATCGTCACCGCCATATCGGTTCGATCTTCCTCGGAAGCAGCAACAAAGGTTTCACCGCCACCTTCGCCGGAGATGGTCGCCGCACAGGAATAAAAGTCTGTCCACTCGGCGATTTGGTTGCCATAGCGGTCGGTTGTCACACTTTTCTTCTGAAAAGTCACGCGGGCGTTTAAGAGCGAAATATCCATCTAAAATCCCGCCTTTCTGTCTCCGAATAAAAGCGAGCGAAGCGTGAGGGTGAGATCATGATGGTCAGCTTCTTCCCGGTGCTCAAAGAGGTAGGCGACGGTATAGAGAATGGCCACGGGTGCGTTTTTGACTCCGGCAAGTTCTGTTTCCAAGTTCAGTCGCGCGACATTCGCGACAAGGCTTGTTGCATTCTGCAAGAGGTCTGCAATGAGCACGTCGTCATCGGAAAAGTCGACACGCAGATAGTTCTTTGCTTCCGCAAGGCTTATGATGTCCATCTCTTCACATCCTCCTTTCTATGTAGGAGCGGCACCCGATAAAGAGTGCCGCCCCAGAGTCACTAATGCGTCATACTTATGCTCCAGCTTTCATCTGCAAGAGCTGAATGCCTTCCGGCAGAATGACCTTGCCGTCTACACGCTCGGTAGCGACGTAGCCGATCTGGCCGTTCGTGGCGTAGAGCTCATTCAGGCGCTGTACAGTCCGGCCCGCGCGGTCGCCAATCCAGTAGTTCTTAAAGTCGCCAAAGGCAACGGTGAGTGCGCCGGCGGCAACTACCGGTGCATAAGGCGAGGTGTAGAGTTCATAGCCCAACAGTCGGTCCGGCTGGCCGGCCTGCAGAGAAGGCTGCCACAGATAGGCGCCGTTCTGGTCTTTCAGCTTGCGAATCGCTGAGATGGTAGCATCGTTCATGAGGAACTTGGCGTTTCTGCGGTAGGGCGATTTCAGCGCATACACAAGGCTGATGAGTTCGTCAGCCGTGATGGCTGTCGAGCTTGCCGCCGTCACGCCCACAGTGCCGCCCTGTGCGGTGAAGATGCCGGTGGGCTGGGTGGTGCCGGTGCCGACGCAGAAGGCCTCTTCCTCGGCCACACCGAAGGCGCGAGCAAATTCCTTCATGAGGTAATCTTCAATGTCGAAGGCCGAATCCTGCAAGAGTTCCACACTCACGCGGCAGAGATCCGTCAGCTTGAAGGCATCAATCTGCTTCTGGGCAAAGGTGGGATTACTCTCCGTATAGGCGGCATTTTCTGCCGTCCACTGTGCCTGGGAGTGGGTGTTGGCAATGGGAATCTTGCGCTCATGCTGGGTAGTGATGACTTTCGCGAGCGAGCGCACGACGTTTTCTTCTTCCAGCTGCATGACAATCTCTCGCTCAAATTCCTCCGGCACTAGGTAGCCGCCGTCGGCATCCACGCCTTCGGAGAGGACGTTGTGAAGCAGCTGTTTGCCGCGCAGGTGACGGTCAAAGTCCTCATGGTAAGCATCCGAGGCGCGACCGGCTTTTTCCGACTTCATGGTCATCGCGCGTTCCGGCTTCTGTGTGAGCGGCTGGTCAACGGGACGGGACAGTTCCGCTTCGATCGCATCGCGCCGCTCCATGCGCTTGACCTCGTTGGTCATGGCATCAAGGTCTGCTTCCATCTTGTTGTAGGTTTCATTGTCCTCGGCGGACAGGTAGCCCATGCTGTTGCGGTGGGTTTCCAGAAAGCCTTCCATCGTGTTCCAGAGCTTGGCACGTTTCGTTCTCATTTCGGTGATATTCATAACTTCATCCTCCTGTCAGTTAAAGCAGTTTCTTATACAACGACGCTTTGAGGTCATCCACAGAGCGTCCCACGGGTAATTCCATTTCTTGCGGTTTGAGCTTTTCCTTCATTTTCGCGACAAGCGCCCGGTCGACGGCCGAGGCGGCGAAGCTGTAGCTCTCCAGATCTGCTGGTACTTCCCGTTTGCTATCGGTCAATAGCGCATCGGCGAAGCCCAGATCGATGGCTTTTTTCGCATTCATCCACGTTTCATCTTCCATCATCCGGGCGAGCTGTTTTCTCGGAAGGCTCGTGCGGATTTCATAGGCGTTGATGATGGATTCCTTCACTTCCTCCAGCATATCGATGGCTCGCTCCATCTCTCCGTGATCGCCAAAAGCGGCGGTAGCCGGATTATGGATCATCATGAGGGCGGTCGGCACCATGAGCACCCTTGTTCCGGCCATGACGATGACCGAAGCGGCGGATGCCGCAAGGCCATCAATCTTGACCGTGACTTCACCGGGATAATCCATAAGCATGCCGTAGATTTGGCTGGCGGCAATGCAGTCGCCGCCCGGCGAGTTGATCCAGATGGTGATGGGACCGTCTCCGTTAAAGAGCTCTTTTTTGAACATGACGGGCGTAATATCATCGTCAAACCAGCTTTCTTCAGCAATAGTGCCGTACAGCTCAAGAATCCTTTCCTCAGCGCCGTCTTTGCTGTGGTTCACTTTCCAGTTCCAGAATTTCTTCTTCACTGTCTTGTTCCTCCTTTCCTGATGCTTCAAGGTTGGCAAAGGCTCCAGCATGAGAGAGCGGGAGCATGTTGCCGTTGATTAAATACAAATCGCCGCCTTCCTCTTTGGGAATGCGGTCGAGGTTTTCCAGTTCCCGGATGTCATTGGCGCTCATCCATCCGTTCTGACGGGCTGTGGCGTAGCCGGACATACGGCTTTGGTAATCCCCTCGTAAGAGGCCCTCCACATTGAACTTCACGAAGAAGTCCTGCTTTTCCTCCGGATTTAAGAGCCTGCGGTGAATGGACTGTTCCCAGCGCACCACCCAGGGATCCAGGGTGTAGGTCACAAACTCGAGGGACTGTTGTTCGATATTCGAGAAGCTTGACTTTTCCAGGTCGCCCACCATATGCGGTGGCACGCGGAAGATGCGTGCAATCTCATCGATTTGAAATTTGCGCGTCTCCAAGAACTGTGCCTGCTCCGGGGAAATCGAGATGGGCGTGTATTTCATGCCTTCCTCGAGGACTGCGATCTTATTGGCATTCCCGGAACCGCCGAAGGTAGCCGTCCAGCTGTCACGAATTCGCGCTGGATCCTTGATGGTGCCGGGATGTTCCAGCACACCCGAAGGAGCGGCGCCGTTGGCAAAGAATTTCGAGCCGTATTCTTCCGTGGCGATGGCAAGGCCGATGGCGTTTTTGGCCATGGCGATGGGGCTGTAGCCGACCAGTCCGTCAAAGCCCAGTCCCGGAATATGCAATACGTCCGATGGTTTCAGCCGTACCGTAGAGCCTTTCATGGTGTGGGCTTCTTCAGTCTGTCTGGCGTATTCGTAGTAGAGATTGCCGTCAGACCCACGGTTCACGCTCATCTTGTTTGGCATGAGAGGATACAGGGCAACGACCTCGCCCTTACCGTTTCGAATAACCTGCGCATAGGCATTGCCCCACAGAAGCAGATGCGTCATGAGCGTCTCCCGAAACACGAAGGAGCTCATCTCGGGATTGGGCTCATCGTGGAGGAGCCGATAGAGCGTATGCGTGAGCGCCTTTTCCTTTCCGCCATCCTCCTTGTAGCGGTAGAGGTGAAGCGGAAGGCCTGCAACAGCTTCGGAGAGAATCCGGACGCAGGCATAGACCGCCGTCATCTGCATGGCGGAGCGTTCCGTGACGGCTTTGCCGGACGAAGATCCTCCCAGATAAAAGGCGTAGCTACTGCCTGTTGTGCGGTTTTCCGGCTTATCTCTGGACTTGAATAGTCCGCTAAAAATCCCCATAGGCTGCTCCTTTCTTAGAAAAGACAAAAGAAAAGCACCTCTTTCGAGTTGCTGTGAGTTAATTATTAAAAGACGAGAAGGCCCCGGCTGTCGTAGACTGATTCAGACGTATCATTTCCGCACCGAATCGCCCGGTCGAGGGCCATGATGGTGGCGATAGCGCCGTCGATCTTCTCGCTGGATTTGGCCTTATCCGCCTTGATGTTTCCGGCAGGGTCTCGTCGGATGTAGATGTTATCCATCATCCACCGGAGGACAGGATGACCGGCATGGGCAAGGCGCTCTTCCAAGGCCAGTTTCATCAGCTCTTTGGTGGGCGGGCTCATGTCCTTAAAGCCCTGTCCGAACGGAACGACCGTAAAACCCATACCCTCGAAGTTTTGCACCATCTGGACAGCACCCCAACGGTCAAAGGCAATCTCCCGGATGTTGTACTTTTCGCCCAGTTCTTCGATGAAGCTTTCGATAAAGCCGTAATGAATGACGTTGCCCTCGGTGGTATTGAGAAAGCCTTGTTTTTCCCACACGTCATACGGTACGTGGTCACGCATCACCCGAAGCTCGAGCGTATCCTCCGGCACCCAGAAGAACGGAAGAATATCATACTTGCCTTCCGGATCCTCCGGCGGAAACACCAGTACAAAGGCGGTCACGTCGGTCGTGGAAGAAAGGTCAAGACCACCGTAGCACACCCGTCCTTCAAGCTTATCCGGATCGACCGGAAAAGCGCATTTATCCCAGACCTCCATGGGCATCCAGCGCACCGCCTGCTTCACCCATTGATTGAGCCTAAGCTGGCGGAAAGAATTCTCTTCGGCCGGGTTTTGCCTTGCCGACTCACAGGCGGCCTTGACCTTATCCATGCCAACCGTGATACCCAGTGATGGATTGGCTTTCTTCCAGACCTCCGGGTCCGTCCAGTCGTCGTTTTTGTCGGCACCATAAATCACCGGGTAGAAGGTCTGATCGACCTTTCGGCCTTCGAGGATGTCCTTGGCTTTCTGGTGCGTCTCATAGCAGATGGAGTTTGTGTCCGTGCCGGCCGTCGTGATAAGAAAGTAGAGTGGCTGCATCCGGGCATCGCCGGAGCCTTTGGTCATGACGTCAAAGAGCTTGCGGTTGGGCTGCGTGTGAAGCTCATCAAAGACCACACCGTGGATGTTAAAGCCGTGCTTGGAGTAGGCTTCCGCTGAAAGCACCTGATAGAAGCTGTTGGTTGGATGAAAGATGATGCGTTTCTGGGAGCCCAAGATTTTCACACGCTTTTTTAAGGCGGGGCTCATGCGCACCATATCCGCCGCCACATCGAACACGATTGTAGCCTGTTGTCTATCTGCCGCACAGCCATAGACCTCGGCGCGCTGTTCGCCATCCCCGCAACAGAGGAGGAGTGCCACGGCTGCGGCAAGTTCGGACTTGCCCATTTTCTTGGGAATCTCAATGTAGGCCGTGTTGAACTGGCGGTAGCCGTTTTCTTTCACGATGCCAAAGAGGTCGCGGATGATGCGCTCCTGCCAGTCAATGAGCTGGAAGGGCTTACCTGCCCACGTGCCTTTGGTGTGCTTTAGGCACTCGATGAAGGCGACGGCATAGTCAGCCTTTTGCTTGTCGTAGTGGGAGCCTTCCGCCATAAAGCGGGTCGGCTGGTAGTCTTTGAGCTTTCGCATCACCATGCATCCTCCTTTCCAAGGCAATAAAAAAGACCGCTCAAGCGATCTGCGTCCGGTTTCTATTTCTACGAGAAAGAGAGCCTGTGCGGCTCCGGTTTCTCTGGGTTTTTCTTTAGGCGTTTTGCTGTCCGAGCCGGTAGGCGGCCATCAAGGCGTCTTTCAGGCTCCAGATGCTGGTTTCGAGGAAGTCTTCTGCGTCGTTTCCGTGTTCTTCCAGGTCGCTTCTGCCTTCCAGCGAGGGCATCATTTCGAAGGCGAGCTTGGTGATTTGCTCTTCGATCTTTGCCTGTCTTGCTTTGGTTGTGTTCTGGAAGATTTGTGCTTTGTGTTCCTTGTTTGTCATGGTGTTTCCTCCTTTGGTGTGTTCTTGTTGTGTGTGTATATTCGCTCTACACGGGAGGAATAGCAAGTACTATTTCGAAGATAAATGGCTATTTTTCAATGGTTATAACGAGGAAAGAAGAGACGAGAACCTCCTCTTCCAAGGGTGTATTTTCTTTTCTTACAGTCCCAGCTTGAAAGCCGGCTTGATTTCCTTCTCTCCGGTGCGCCAGTCGTTGAAGCGGCTTCTCACCTTAGTGAGACCGTTCAGTTGGCATCCAAGCTCGACGAACTTGTCGATCGTCTCGATGATGCCGGAGAAGGCGGAAGAGATGGTGAACTCTGTGATGCCGAAGCGTCTGCAGTCCCGGAGGATTTCTTCAATATCGTCGTTCCAAATGACATCCGCAAAATCCGGCACGTCATTTCCTGCTTCAAGGCTTGTGAGGTAGGCAGTTCCGAAAGTTGGGTTCACGCCAATCTCCTTGTAGTAGATTTTCTGTTCTTTAGCTTGGTCTAAAATCTCGATGTGTTTCATGGTTTTCCTCCTTCGGTGTGCTTGTCTTGTTGTGTGTATATTCGCTCTACACCGAAGGAATAGCAAGTTATATTTGGCAGATAAACGGCTATTTTTCAATGTTTTCTTCACCTGTGAGGATGAAATGGGCATACGCTTTCGGGTGCTCTTCGATGAACAATACCAGCTCATAGTAGCCCCGCTCAAAGGCAAGGCGCTGGAATGCGGTTGCATCGAACATATTTGTCAGGCCGCTATCCCGGATGGTAAGAATCTGCTCTTTGATTTTCCCGTCCATCACCGGCCTACCTTTCGGACCTCATCGACGCCAAAGAGGACGTTTAGCCCGGAGCCGTTCTCCCAGCGGACGAGAAGGGAACCCATATCGTCAATGCCAATCACGGTGCCGAGTGTGCCTTGTGGCGGAGCCTGCACATCGTCCATGTGCAGAAGCTCCACGCGAGAACCGACAGGATATTTGAGTCGCAGATGTTCCAGTAACTCTTTACGCATTCTTCGCCTCCTCATCTGGTTCTCTAAACTTGAAGGAGGAGGAGCCTTGGAGGTTTTTCAGGAGTACCTTACGCGTTTCCTTGTACTCTGCGCCAATCATCCCGATGCGAAGGAGAAAACAGCGGAAGTAGTATTTCTCGTTTTCCACCTCATGGTCTTTTCCGGTGATGCGCTTGGCTTCTTTTGCGTGCTTGGCAAGAAGCGCGATGAAGGTCGTGTAGGCTTTTACTTCATCGGCAGAGGGAATCCGGTCAAACCAGGGGAAGTGAATCTTCTCCTTGGTGATTTTGATTGGTGTTGCGCTAATATCGAGCGCATGCTGAATGACGCTTTTCTTCGAGGCAACAACCATGGTAATCCGATAGATGGCCGACTCGCTGAACCCTTCTCTGGGAAGGGAGATAGTAAATAAGTCAGCATCCTCTTCCGCTTGGAAGCCTTCAAAGGCGAGTGCCTCGGCGATCTTTTCCATCCGTTCCTCATCATCGCTAAGCAAGGTGCCGAATCGGTCGACGGTAAAAGAGCCTATCGTATAAGCGTAGGTGGGAATCCCTTCATATTTTGCTTTCTCTCCGGTCAGCTTCTCCAGTGCGCTGACCAGCGGCCTTCTTTCCTTGCCTTCCAGGTGATAGTGTCTTTCCATGACTGTATTCCTTTCTGCTTTTCAAAAGGTGTCTTTTGGTATGTCTATACATCACTCTGTTGGTGAGAAATAGCAAGTTATTTCTTCTGGTTTTCTGCGATGGCGCGGAGCACATATTCTGCACACGGTAGGGCAATGCCGTTGCCCCAGAGTTTGTACTCTGCGCTGTCGGAGTAAGGGTCAGCGAGCCATTTTTGAAGCTGTTTGTCGGTCTTAGGCTTTGGCGTTTTTCCCTGTGTGCTCTGCCATTCCAGAAAGACTTCACGCCAAAAGACAAGGTCATCTTCTGACGGATTCGGCTCGCTCAAATCTTGGCACCAAGGATCCGGAAAGCCCATGAGTCTGGCACATTCCGTGGGCGTAAGTCGTCTAACCATATACTGTGGGCCGCTATTTGCATTGATGATGGGTGGATCTTTGTAATCCGAAGCGACCAGCGTATTAGCCTGATCTTGCAGGGCGTCGGTGTGGTATGAGGTCTTGCTTGTGGAAAACACCACGGCAATGCCGCCCTGATTGCAGGTTGGCGAAATACCGGATGTGTCGAGCGTTTTGGAGAGGTCTGTTTTGTATCCGAAACGTCCGGCTCCGGATTCTTTATGAACGGCATTAAAGCCGTAGGCTACCGGTTCAAAGAGCGTCTGGTCGTTGTGCGTTGAGATGGTGGCGGAGAGGTTATCCTGGACCAGCGCACCTTTCCCGCCACCTTCTTTTCCTGATCGGATTTTCAGCGTCTTAGGTTCTGCAATCAGAGGCGTGTTCCCGCCGCCTGTCCCGTAGCGGGCAGTTGTCGCTGGAGCCTTTTCAAGCGGCCCGGTTACTCTGGCGTCTTGCGGGTGGTTTTCAAAGACCAGCGGCGGATGATTGGCTTTCGCTCTTAGCGTATTCGTGCGGTTCTTAATAACGTCCATTCGGCTGCCGCCCTGATCCATCAGGCAGAGCGTGCTTGCATCTCCAGCGCTTCTTTCAGAACGTCCGGCAGTGCTTTGCCGCGCTCCGATGCCCTTCGAAGAATTCCCTGGCAGGCCATCGGACTCAAATAATATTTTTCCGGCACCTTGTCCTGCAAAATCTGCGATAAGGTAGATTCTCTTGCGTCTCTGGGGGACTCCGAAGTATTGCGCATCCAAGAGTCGCCAGGCGATGGAGTAACCATCTCCCATGATGGTTCCGGCGTTTGTCCATTTTGAAGATGCAGGTACAGATATGGTCTTATCTTTAATCCGGCATAAGGACTCAAGGACGATCCGGAAGTCTTCTCGGCCTCCGGATGAAAACACGCCCGGGACATTTTCCCAGACGCAGTAGGTTGGATAGTTTCCATGCGTTTCCTCCCGCATTTCCTGTATGATTCGGACGGCTTCGTAGAACAGGTTTGACCGTGAGCCTGACAACCCTTCACGCTTACCTGCAATGGACATATCCTGACAGGGACTGCCAAAGGTGATGATATCCACTGGAGGAAGGGTGCGTCCGGACAGGTCTTCAATATTTCCAAAGTGCTGGACTTCCGGGAGACGTTTGGTGGTTACGCGAATGGCAAAGGGTTCAATTTCCGATGCCCAGATTGGCGTGATGCCGACGTGTTTTGCGGCCAGTTCGAAACCACCGGAACCGGAGAAGAGGGATCCGAGCGTAAGATTAGGCATGATCTTCCTCCGGCAAGCTTGCCACGATTTCATCATAGGTGAACTTTTCGCCGTTACGGAGGACAAAAACGTCTTTTGTTTCACCCTGAATGAAATTAACGTAGCGGTTCACAGCCACATCCACAAACTTTGGTTCCAGCTCAATGCCGTAGCAAATCCGTCCCAGCTCTGCACTCGCAATGAGCGTGGAGCCCGAGCCTAAGAAGCCGTCCAAGACGAGACCATTGGTCTGCGTACATTGCTTGATGAGATAAGCAATGAGCGGCACAGGTTTGGAAGAGGGATGGCCAAAGCCGTCCTCTTTGGAATCGCGAATCCCGCCAAATTCAAACACGCTCGTCTGCTTTTGATCGCCGTACCAGATGTGTTTGCCGTCTTTGCGCCATCCGAAAATGATGGGCTCCATGTTGAATTTCCAGTCCGTGCGCATAAAGGGCGCGCGGGGCTTTTTCCAGATGAGACCAGCTCCAACCTTGAATCCCGCATCTTCGAAGGCGTCGTAGAAAACGCGCGTCTTCATGGTGGCGTAGAATTCGTAGATGGAAGCGTCGATGGTCATCGCTTCTTTGAAGTTAGTGAAAGCCTTCATGAGAAAGGCGTAGGCTTCTTTATCGGAGAGGTCATCGTTTTTGATCTTGCCGGACTTGCTCTCGAGGTTCACGAAGTACGGCGCATCCGTGCAGACGAGGTTCACCTTGATCTCCCCAAGAAGATTCTGGTAGGTTTCCTTTTCAGTCGCGTCTCCACAGATGACGGTGTGCTTTCCCAGATGCCATATGTCACCGGGCTTAGAAAAGCACGGCTTTTTCAGTTCTGCCTCGATGTCGAAGTCATCCTCGGTGCCTTCCGCGTCCGTTTCAAACAGCGCGGCGAGTTCCTTCTCGTCAAATCCGGTGAAGGAGAGGTCATAGGCCTGCTCCTGCAAGGCTTCAATCTCCACCCGGAGCATTTCCTCATCCCATCCGGCATCGAGCGCCATGCGGTTATCTGCGAGAATGTAGGCTTTCTTCTGCGCTTCGGTTAGGTGATCCGCAAGAACGCAGGGAACCTCTGCTAAGCCTTCGGCCTTGGCAGCGAGAATGCGACCGTGCCCTGCGATGACGTTGTATTTTTCGTCAATGATGACGGGATTGACAAACCCGAACTCTCTCAGTGAACTTCTGAGTTTATTAATCTGTTCGGCGGAGTGCGTCCGGGCGTTATTCACATAAGGTATCAGTTTGTCGATGGGAATCAGTTTCAGATCCTTCGTTGTATTCATCCGCGTACCGCCTCTCTGAGAATGGCTGTTTTGTCGAGTTTCTCCCACGTCGCATGGGAAGAGTTTTTGAAATGCCCGTACACGGAGGTCTCAGAATAGATGGGGCGCATCAAAGAGAGCGTCTCAATGATGGGCTGAGGGCGAAGATCAAAGGTCTCCCCAATAGCTGAGAGAATCCGTTCATCGGACGCTGTGCCAGTCCCGAAGGTATCAATCGCCAAAGCGACCGGTTCGGCCTTTCCGATGGCGTAGGAGATGGAGATTTGGCACTTCTTTGCAAGTCCAGCCATGACAACGTTCCTTGCGATGGCACGCGCCATGTAAGCGCTGCTTCGGTCGACTTTGGTCGGATCTTTGCCGGAAAAGGCACCGCCGCCGTGGAGCGCAAGACCGCCGTAGGTATCGACCATGAGCTTTCGCCCAGTAAGTCCGGTGTCTGCTGCATGCCCGCCGAGGACGAAGCGTCCCGAGGGATTGATATAAATCTCAGTTTCTTCGTCAAAGGGAAACGAAGCAAACGCAGGAATCAGTACCTTCTCTCGGATTTCCTCAGCAAACTTACTAAGATCCTTTTGCCGGGTGTGCTGGGCGGAGACGACGATGCTCTTTATGCGAGCGGGTTTGCCGTCCTGATATGCGATAGATACTTGTGCTTTGCCGTCCGGACGCAGTCCGTCAATTGTGTGCTCTTTCATACATCCATCGAGCTTTTGGCAAATGCGGTGCGAAAGCACGAGCGGAAGTGGCAAAAGCTCAGATGTTTCATCCGTGGCAAAGCCCACGACCGTTCCTTGGTCTCCTGCGCCAAGCGCCTGATCTGTGCTCGTTCTTGTTTCCAGCGCATGGTCGACACCGCCCGCAATGTCCTGGCTTTGCGCGTGAATGTGGACATGGATATGAATGCGGTTTGTGCTGTAGCCGGTGCGGCGCAGCACGTCTTTCACGATGGATACGATGTTGAGCGTTTCCTTGCAGGAAATTTCACCGGCTACATAGATGTTGCCTTCGGTTGCCATGGCCTCACAGGCACACCTGCCTTCCGGGTCAAGAGTAAGAACTTTGTCGAGCACGGCGTCTGCGATTTGGTCACAGAGTTTATCCGGGTGTCCCGCGCGTACCGATTCGGCGGACTTTATGGTTTGTGTCATGTGTCATCCTTTCTTGGAGCGTAAGAGCCGCTCCATCATGTCATCCGCAGGCGTCTGGCCTTCATAGGAGACGGTGGAGTTTTGTTTGACAATGTCGAAAATCTCGTACCAGAGAAGATTCGCCTGCTTTTGAAAACTCTGGCTCATGGTGACGAAGGGACTGGTCACCACGCCTCCGGTCGTGGGGTGCTTGCCGAGAAGGCCGAAGTGCGAGATGGCATTTTCACACTGGATGTAGCGGGCGAAGTTCTGCGCATAGGCTTCAAGAAGCCTGGGCGAGACGAGATGTTCACAGCCCCTGTCCTTGAGCCACTGCCAAGTTTCGCGGTAGAGGTCATCTGCGTAGAAGGGCTGGCCGTCTTTTTGCTTGGCGGAGAGATATTCGCCGGGTTCCGGCATATCCATCCCTTCAAGCTCTGCGCCTTCGCCGATGTCTGCGCCCACCAGGAGGGTGACATCCGGCAGTTCGGGGTTTAGAATCTTGGCGGATTTTCCGGCGGCAATCTTGTCGATGAGCGGATCGGGTTTTGAACCGGCTTTGATGCGCCTTCCGCCACGGTTCGTTCCGTCTTTTGCCATGTACGTTTCTCCTTTCTGTGGGATTTGGGCATGAAAAAAGGACGCTTGTCTGCGTCCTTGGGTTTATCGGGTGTTTGAATTGGCTTTTTTACGCGCGGTTCCCCGGCACCGTTCCCCGGGGCATGGCGCGTAGAGATTTCGACTGCCCCTCGGGGTCCGAGAGATTTCACTTTTCACCGATCGCTGGACTTGTTGTTTTTGCGCTTATGCCAACGGTCGCCCATTTCTGCGGTAATTCGTGAATGGCACTCATGGCAGAGCGCTTCGAGATTTCTTTTCTCGTGGGTACCGCCGTGTGAGAGCGGCAGCCGGTGATGCACTTCGGTCGCCTTGGTATAGCGGTGTTCCTTCAGGCACTCCTCGCAGAGCGGGTGCGTGTGGATGTAGCAGTCGCGGATGCGCTTCCACGCGCGTCCGTATTTTCGTTTGGCATTCCTGTCCCGGTCGTAGGTCTCGTATTGTTTATCGTAGAGCTTCTGGTGGTCTTGGCAGAAACGTCCTTCGGTGAGCTTCGGACAGCCGGACCAAGAGCAGGGTGTTTTCGGCTTGTAGGGCACTGCTTGCTCCTTTCCCAATAAAAAAGCTCCACGGGATTTCTCCCACAGAGCCTCGCTATAGTCTTTGACACTAATAGAATATCAGGTCAAACAGCAAAAGTCGTCCGCGATATTACTCATTGGCTTTTCATCCATAAAGATATATACTGCAATAAATGAATTAAAAACTAAATAAAACGGACAGGAAGGTCGCATCTATTAGGGATAATAAATATGAGAAAGAAAAAAATTTTAAAAATAATTTTAATCATTTCGATAAGTATTCTACTCCTCCCCATCCTGTATATTGCGGCATTCTCTATTTATATGCGGATCCCTCAAACCTATGTACTAAAGCCGGCATCTCCATATACCGGTGCACAGCTTGTAACGAAGACAACTCATAGTTTTCGAGGGAATCATAGCAAAATTTATATTCGGTATCCTAATAGCACAAAATTAATTGATACAGAAGAGAGTTTTGGCGTGGATGAGGCTCGACCTGGTCTTACAAGAGACGATGCCCCGTATACATTGACGTGGATTAACGAGCACGAGGCAAAAATAGAGTATATCTATGCGGGTCCAGACGTGATTTATGAAGTGACTATCCAATACTAAGTGTAGTATTGGATAGTCACTTTGTTTTAACCTTAGCCGAGATTCAAGTATAACCATTTTGCAAAGGATAAGATGCAAGCATCCTTTACCTCTTGAGGACTATCAGAGTTATCATTTTCAAGTCTGGATAATAAATCTGCCAAAGCGTCTTTTACGACATCTTTCACTTTATCCTTAATATCCATCACATCTTTTGTAGCATCGATGTCAGTCAACAAACCCATGAATTGGGTGCCTCGATCAGTGGTAAAAATTTTTTCAAAACTAGCCCCAAGGTTTCCATCACTCTCCTTTAAATTTTGGGATAGAACAATTGCATATCCATCCGAACAAAGGTCAGTATAATTACAGGGATTCTCTTTCGCATTTGGCGCATGAGGCAGATCTTTTTTAGGAAACTCTCCTCCTACATAGGCACGGGCTATTTGTTGTAGATTATCACCCGGATTGTTTTTATAATAATCCCTTACCAATCCATATGCAGATACCAGATCTCCGGCCCAGCCATTCCATGAACCTGGATTCAGCGTAAAGTTGTAGTAGCTCAGTGTGGTAATCGCCAAATGCGGTAAATCAATCACTCCTCGCTCACCATCCCACAGTGAATTTTTATCCCCTGAGATATAATGAGCTAAATTATTAGCAAGTGCCGGATAATTTTTTTTCACATAGACATCAAATACAACATCATAAGTGGTACTTGAGACAATGGAAAATCCTATCCCTTTTAGGGCATCATCGAGGAAATAGGATTTGGCTAAATATTGAAGAGCACCAACAGCCGGAGAATAAATCGGCATTTTCAAAAGTGGATCATATCCATTCTTCAAGTAATCTTTATAGGCATTTTCAAGTTCTTTAATGAGTGGAAAAACAGTAGAGATCTTTGTCTTGGCTGTCAGCTCCGTGTTGCTAAAAGTTGTTGGCAGTGAATACGGGAAGTAGTTCCCATTTGCTTGATTAACTGTTGCACAAGCCGGAATTTTTCCACTGTAGGCAACCTTATCTAAATCCCAACTTCCGCTATAACCTGAGATCTCGTAAAACTGGTCATAATTCCAATTCTTTGGAATGGGGAAACCAAGATTCCCACTATAGCCGGTAGACATATCTGCCACAAAACTTGAAATGGCATATCCTGTATCACAGATTCTTGTGCAAATATTCCGCGAAGCATAAATACCAACCGAATATTCCATCGATATGGTTTCATTTACACCTTTGAAGTAGGGAAGAATATTGCTATCAATTTGATAATCGTAGGCATCCATATCAACAGCAAAGTAAATGACGGTTGATGGTACGCCCTTTGCCAAGGCAGCCTTACTTGCTGTGGCACCATCTATTTTGCCTTTAGCGTATGTGAAATTACTGATCTCGCGTCCATTATCTTGAAAAATGGGAAAGTATTTCATCCCGCCTTTCGTGATACGATCCAGTTCTCCTTCTCGGATTTCCTTGAAAGATCCACCGGTCAAATACCGACCGACAATCTGATATCCATCTCCTTTGAGCTTTTTCAACAGTGACTCGGTAATCTCAAAACGAGTGTCACAAGCTTTTGCGGCTCGGTCCGGATTTCCTTTGCTCGTCAAAAGCGACATCCAAGCGTTCACGTCAATGGAGCTTCCTTTTGGAAGTGCATAATCTGCTCGGAAAGTTTGTAGCGAAGAATTAAGAGATTCATCCCAAACATTGTTCATCCGGCAGTTATATCCTAAACAATTTAGTGCTACTTTTGCGAGCCATACCCAATTGCCATAGCTGCTTGCGTTAGAAGATGTGATTTTGCACAGATTGCTTTTTGTTCCATTGCCAAAATATCCGGTCGCATCCTCTGGAGAGTACCCTTCAAGAGATTGAAGAATTTGAATAAGCGCAGTATTCATTTCTCGACCATAGATCCCATCACAAGGTATGATCCCTGTATAAGTTTCATATTTTCTGTTGATCTGCTGCTGTATCTGACGAATATCATTTCTTCCGCCGTACGACGCGAGTAACACAAATTGTTTCATGGAAAGCAGAACATCCATCAATTGCAACGTTACGGTAGAATCACCGCCAATGCCCATATCGTCTTTCAACTGCCGAATTCCCTGAGCTGTTCCATCATAGAAATGTTTGGTAATATCCCCGTATTCAGCACGATACCCCTTGCACCAGAGTGAGCCTTGGATAATGGCATATACGTTTGACTCGGCTTTATCATTCGATGCTTGTTGCTTCACGCCATTCGGATAGCGCTTAGAGAACAGTTGACGTGAAGACGGGCCAAAATTATCCGCCGTGTTTTGAATGCCAAGCTCAATCTGCAAAGCGCGTGTCAACGCATTGATTGTTGCCCATCCCGTATGACCGGTTATTTTGAGCTTTTTGAATCGACTATCTGAGCCATAGGTTTTGTTTAGCCATTCTTGTGTTTTTTGTACCATGACATCCATAATAAAATCCTCCTAAGATTATTTCGGCAAAAGAACTGCAGAATATTCATCCTTTTGTCTTAATGAGTGGCAGGACATAAAAAAGCTCCTTGGGATTTCTCCCTTGGAGCTTCGTCCTAGATTTTTACACTATTACTGTATCAGCCTTCAACCGAAAAGTCGTCCGCGATATTACTCATTTAGCCTTTGCCGTAGAGATTCACCTTCAGGTGGTTGATGGCACGGTTCTTTTTGTTGTAGGCGCTGGAGCGTTCGATGTGAAGCCTCTCGCAGATGGTCTGGATCGCATCGGTGCGGGACTCGTACTCTTCAGTCCAGTAGAACTCCTCAAGGCAAAAGCGCTCATCATCCGATAAGGCTTTCCATGCCGGGACAAACCAGTCCATGTATTCCCGGGCTTGACGGTAGCGCTCTTTTAAGACGTCGATCTGATAGAGGCTGTTCGCAAGGCGCGTCTCGCCGGACTGGGGATCGTGGACGTGTGGCATCCCATCGTAGGCCGGGGAGGAGATGCTCATCATGCGCTCGTAGCGTTCCTTGATGGCGTCTTCCGTGTTCTCAATGATGAATTGCATCGAGTGATAGTCTCGCAGCGCCTCAATGGTCGCCGCACGTTTATCGAGATATTTCCAAGTGATATGCATGGCTTCTTCCTCCGTGAAAGATTAAAGTTTCGGCTTCCTCGGATTGGCATGTGTTGTCTTAGATTGTCTTATGCTTTGAGCTGTGCCTTCACGGCGGCGATGAGGGCTGACTGCGTCTTGTCCTTGTGCTTCAAGGCCGCGAGGATCTCTTCATCAATGGTACTTGTTGTTACGATGTGGCAGAGGACCACAGTCTTGCTTTTCTGTCCTTGCCGGAAGAGGCGGGCATTGGTCTGCTGGTAGAGTTCCAGTGACCACGTCAGGCCAAACCACACGAGCGTCGATCCTCCATCTTGAAGATTCAGCCCATGTCCGGCAGAGGCCGGGTGGATGAGTCCCACTTCAAGCTTTCCGGCATTCCAGTCGGCGATGCTCTTTGCACTGTCGATTTTTTGGTGGCGCACCTTAAGCTTTTCGAGCCTTTGCTGGATCCGCTCCAGATCGTGGGCAAACCAGTAAGCTACCAGAAGCGGTTTGCCGTTTGCCGCTTCGATGATGTCCTCCAGTGCATTGAGCTTTCGGTCATGAATGGTAATGGTATCGCCATCGTCACCATAGATTGCACCGTTTGCCATCTGAGAGAGTTTCCCGGTTAGTACAGCGGCATTTGAAGCTGTGACATCTCCACCCTCTAAACTTAAGACCAGTTCTTTTTTCATTTTCTCGTAGAGTTCCGTTTCCAAATCATTCATCGAAACCGGAACCGAAGTTGAGATGAGTTCCGGCATCTTCAGGTGCTCATCGGCTTTCATGGAAATTGTGATGTCTCCAATGGCGCGGTAGATCGCATTTTCCGCATCAAGCTTTGGTTTGTAGGAGTAGATGACCATGCCATTTCGCGCGTCTGGCAGAAAGTAACGCTCACGGTAGCCGCCGATGAAGCGGCCCAGACGCTTTCCCATGTCCAAGAGCTTGTACTCTGCCCAGAGGTTCATCAGACCATTGGCAGCGGGTGTTCCGGTCAGACCGATGATGCGTTTTACCTTCGGGCGCACCTGCATCAGAGCCTTGAAGCGTTTTGACTTGTGATTCTTGAAACTTGACAGCTCATCGACCACCACGGTGTCGAAGTCAAAGGGATAACCGGATTCGCGAATCAGCCAGTCGATGTTTTCCCGGTTGATGATCGTGATGTCCGCCTTTTTGGCAAGTGCCGTTCTGCGTTCCTTGATGGTTCCGACTGCCACGGCGAAGGTGAGGTGCTTCAGGTGATTCCATTTCTTGATTTCAGCTGGCCATGTGTCGCGCGCCACACGAAGCGGTGCGATCACCAGAATGCGGTGTGCGGTGAAGGCATCAAAGAGAAGGTCGGATAGAGCCGTCAGCGTGATGACGGTTTTGCCTAATCCCATGTCCAACAGTACGGCACAAACGGTATGCTCTTCGATGTACGTCGTGACAAAGCGCTGATAATCATGTGCTCTGTATTGCATCGATCACGCCTCCGATTTTCGTTTCTTCGTCCAGCACAAAGACCAGAAAGCCTAAGTGCCGAAGTTGCTCGTGACGTTTTAGTTGCAAGGGACGAGGTTTCTTGCCAGGTGCCTTTAGTTCCACGAAGCCGATCTTCCCATCAGGGAGTAGACAGAGCCGGTCAGGAAGGCCACTCATGGAAGGACTCGTAAGCTTCAGGCAGAGTCCGCCTTTGGCTTTGATGGCTTTGACCAGTTTCTGTTCCAGCTCTTTTTCCAGCATTTTCAAGGCTTAATCCTTTCTTGGTGTCGGCCGGTGATGCCCCATACATAACTTTCTCTTAAGGCGTTTTTTCTGAAAAAATCGCCCTAAAGGGGGTTTATGTTTGAGGCGCCACCCGGCGACACCCTTTAGTCCATAAAGTCCTCTGCTAAGAGCTTGAGTCCTAAAATGAAACGTCCATTCTTTTTTCGTTTTCGCCCAAAGCCTCGGTTCTCTAAGGCAGCAACGAACTCATTATTACTGCGCGTAAACTCACCGGTACGATTGCAGAAATCGCGATACACTTCGTACAGTATGCCTGACGCTTCCTGCGCAGCTGGATCCAGCTCGCAGCAGGTATCCAGAAAGTGCGAAAGCCAGTCGTTGGATTCCCGGTATTGATTGATGGCCTCCCGCACACAGGCCGGCATGTCAAACTTGAAGTCTTCCGCGATCGCTTTTTTCGCACCTTCCATCATCCACGTGAGAACGTATGGTGCGGCATGGTCCGTCAGGTACTTGGCGTAGTTTTTGATGTCGCTTTTTCCTTCGATCTTGGCGGTAAAGGGGATCACGATGAGTCGCCGCCAGATACCGGTATCCATAGCACCGACTTTCGGCAGATGATTGGTGTAGAGCACCAGCGTATGAGAAGGGATGAAGCTTGCCGGATCCTTGTACTTCTTTTCGGCGGCAATGCGGTCGGTGGAGCAGAGCTGTTTGACGATGGAAGTGGAAAGGCGCATGCCTTCTTCAAGTTCTGCGGCAATGAGAAGGCGCTTGCCTTTCACTTCAGCCAGCTCCGGCTTCACGTTGCGCCGGACATTGGCCGTTAAAGTATCCGCAGAGATCGTTCCGGCATATCTGCTCAGCACACTTGCGATGGTATTCCAGAAGGTGGATTTGCCGTTCGAGCCTTCGCCGTAAGAGATGATGAGCGCTTCCAACTCCACCTGCCCGATGGTGCAAAGCCCTGCGATTTTCTGCACATAGTCGATGAGCTCCTGATCGCCTTGAAAGGTGCGATGGAGTGAATTCAGCCAGAGCTCTTTTCCTTCCTCTCCGGGCGAAACAGCGGTCACCTTGGTCAAAAGATCGGCCGGGTTATGCTCGCGCTTTCCATCGGCACCTTTTGCAAGATCATAGGTCCCGTCCGGACAGTTCAGGACGAAGGGATCCTGATCGAGGCTTTCAAAGTTCACCTCAAGCATGGGCTTTGCCGCCTGCAAGGCTGAGGTGACATATTTCATATCCCGGCGCTTCATAACAAAGGCGTAATAGGTACTCGCCGACAGGAAAGCGAGATACGCTTTTAAGGTATCTTCGCCGATCTGCTTTTCGAGCGTTTTGCCGCCGGCAGTCACATCCGCTTCTTTGACTCCGCCATCCACCAGTGCCTTTCTTGCCGCTGCCAGACGGTCTTTGGCATCTTCCAGCTGCAGGTCTAAGAATTCCTCCATCGCACTGATTGCCCGCTGCTTCGATTCAATCCAGCTGGTGCCGTCATAGCGAAGAAAGTCCGTTGCCGGGGTGAACTTCAGCTCGTCGCCATACTGTTTGACGAGCGCCTTGGCCTGACCGATATCCGAATAGTCCGGCGGCATGAGAGATTCGTTCTTTTTGGCGTAGGCCTCTGGGGAGAGATAACCTTCTGCGCTTTGAACCTTTTTCGCGAAGCGGCAGGCGGAATGCCAGATGGTTCGAAGTTCGGAATCCTCCAGTGGCGGATCGCATTTGGCCGCTTCTTCCAGATAGATTCCTTTCGCCCGGTCGGTAATGCCATAGCGCTTCAGCACTCGTCCAGCAAAGCGGGAAAGTGTGGCATTGCGGGAACCCTCCGAAATTGTGCCGGATTGTGCCATGCCTTCATCGAAATCCGTCTCGTTTAGAAAGTCGGTAATAAGACGAGATCCGTCATGAATTTCGACCTGTGGATCCTTGGTGCCGAAAAAGAAGCGCGCAGCATCCAAAGCGCCGGTATCGAAATACGGAAAGATGGCACAGACCTGTTTTTTGAGCGCGGTGTAGTCCGCTGCCTTCGTCACCGGTTCCATGGGAAAGAACACATGAAACTTCGGCCGCACAGCCTTTCCGGCTTTTGGCTTTAGATGATGACGGCTGAAATGGACAGCAAAGGAGACACCATCAAAGGCAACCGCCACATCGGCGGGCGAAATCCAGTCGTCCGGGTTTTCGGAGTGATCATTGTCGCAATCCACAGCAAGGCAGTCCGATGAGAGAAAGTTTCCGTTTGAGCGGTAGTTCCCTTTGTAGCTGGCGCAGACATAGTCATGTGAGGCGGCCGCTTTCAGACTTTCCTCATCCGTTATGATGGCTGAATGCAGATAGGTACAGTTCGTCGGCGCTCCCGTCACATCCGCAGTAAAAAGGGTGAATTTCATCGGCAAACCTCCTGCATGGCAGCATCGAAATAGCGCACGTTTCTCTTGTGACGCTTGGCATAGGCAATCTCGCGCCCCATGCCAAGCGTCGGCTCACCGAAGGCCCAAAGTTCCGTGCATTTGTCGATGAGGACCAGCCCGAAGAAAAGCGCAAGATCCCGTTCTGTTTTCTCAGACATAAACTGCGGAAACAGTAGGTGCGGGACGATCGGGATAAAACCATGGTCAATGGCAAAACGTGCATAGCGCCTTGCCGCTTTGACGTTGTTTTCCACATCGCCTGCGTAGGGCGAGGCAATGTAGACCAGCGGCATGTAGGGATAGCGCTGAGGCTTAAAAACGGCTTCATAAACGGTGGGATCCGCATAACCTTCGTTATTTTTGTAGAGGTTTTCCATCAGCGGACCTCCTTCATCTGTTGTTTCATCGCGTACCATTCGAGATACTGCTTGCGCTGCTGGTAGTCCGGGACGGAGAGGAGAAGACCGATGTCCACCTTCTGCAGCGTCTCAAGCAGGTCGATCTGCTCTTTTTCCAGGTACGGGCGGATGGAGGTGCCTTTTTCAAGACCGTGCGCTTCGCGGAACTGCCTTGCCGTCATACCGAGAACGATGCGGTTTAGCATGTCGCATTCGTTTGAATAGTGATAGGGCTTCGGGTTGTCGTGGAGCAGGCGAATGTTCTCGGTCAGAAGCGGAAACTCCTGACGGGCGGATACCAGCGTTTTGATGAACGATTCCATTTCGTTGAAGCGGCGGATGTAGAGTTCCTTGAACTTCATCGCCTTTTTGCCTGTGTAGCCCATCGCCAGCATGGTGAAGCCGTCTCGGGTCAGTGCATAGGCTTTCTGTCTGCGGTGACGATCATCGACGTAGCTAATCTCCCCAAAATTGAGCTGAGCAAATTCAAGGCTCATCCCCGAGCTTGGGTAAATCTCCCCAGATTTGGGGAGAATGAGTTTTTCGATGTCACGAATAACGTGGTCATGTCGTTTGCCGAAGAACTGGGCAACAGCTCTCGAGTCGACACGTGCGGTGTCGTGGTTGTCGGCGAAGACGCCATACTTGTCTTTTGGAATGAGTTCTTTCATAAAAAACCTCCATTTCTTGGTGTGGAAGGGAGCACCATTGCACCCATCGTTGGTCGGAAGAAACGAAGGCTGTTATTCGACTTCATCTTGGCTGCCTCGTCCCCTTAACTACTGCTGGAGGTCAAACGGTCCATTTGACGAAAATTGAAGAAATTTTCTCCGCCTCTTCACCTTCCTCTGGAGGTTTGAGAGCGTTTTGAGCGGATGAAACGGATCTTTTTTTTGTGGCAGAACATAAAAAGAAGGGCGTCACGATTTGTGACACCCTTGCTGGAATGAATAGTTTGTGCTGAACTCAATGAATCTATCAGTACAAGCGTCAATCCTTCTGATAAAACTCACACTCGTAGCCGTCGGCATTGAGAACAAGTCCTTTTGCCCACGGCGGAGTGCGACTCATCTGTTTGGCGACCGCTTCAAGCGACATGGCAGGATCGGCCTCGATAACCAGCTCATCGTGGATATGCATCACGATGCGGCAACAGCGGAGCGTCTGCATGGAAAAGGCCAAGATGTCGCGAGCTGTGGCCTGTACGATGTTTTCCACGAACTTTGGACCGTAGGAGCTGATCCGATCCCATTTCTTTCCGGAGGTGATGCCCTCATAGGTCACGCAGGGACTGCCGAAATCATTCATACCGATCCGAGGCTTTACATAGGAAAGGTTCCTGCCGGAGGGAAGCGTGATAAAGAGCATGCCTTTCTTGCAGGCGAAGGTAAGCCCATGCGTCTTTCGCACCGAGCGATGCTGCACCGCATCCATGACCGCTTGGTCAACGTCCCACCAGAATTGCACAATATTCGGATTGGACTCACGCCAGGTGGTGACGAGAGGCTTCAGTTCTTCTTCGGAAAGGCCCGTCTCGAGTGCACCCATGGCTTTTAAGGCACCGACCGATCCGCCGTATCCGAGGGCGAGCTCTGCGATCTTGCCTTTCTGGCGCAGATGGCCATTGATGCCGTGCTTCTCAACATGAACATGAAACATCTGGGAAGCAGAGGCGCAGTAGATATCCCCATTCCTTGCAAAGACCACCTCGCGCCAGCTTTCGTGCGCATACCATGCGATGACTCGGGCCTCGATGGCGGAAAAGTCCGAGACGATGAACTTGCAGCCCGCTTTTGGAATAAAGGCGGTACGCACCAGTTGAGATAAGGTATCCGGCACATTTCCATAAATCATGGATACAACTCCATAATCTGTTGACTTTACGAGTGCACGAGCTTCGGAAAGATCGGGCAGGTGGTTTTGCGGGAGGTTTTGCATCTGTACGAGCCGTCCTGCCCAGCGTCCAGTGCGGTTGGCGCCATAGAACTGAAACATCCCACGTACCCGCCCATCCGCACAGGCGGAAGACTGCATCGCCTGATACTTCCTGACGCTGGACTTGGCAAGCTGGCTTCGAAGGAGCAGGGCTTTCTGCAGTTTCGGCGGTGCTGTCTTAATCAGCGCGGCCACCTGCTTTTTGCCAAGCGACTCTGTCGGCATGCCGTTCTCAGCAAGCCAGTCCTTCATCTGTGCCACTGAGTTGGGGTTCTCGAGCTCAGTGAGTTTTTTCATCTCAGTGAGTAATTCTGTACGAGATTCCTCATCCATACGGATTGCGGCTTCGACCAGCTTCCAGTCAATCTTCACGCCTCGGTCATTGATCTCTTGATCAATGGCGTATTCCTCCCAGAGAAAAGCGAGCGGGGGGAAGTTTCGCAGGCGTTCTTTGATGGCGAGTTCTACTTCCACGTCACGGCGGTTATATTCTTTGAAGATGGTCCATTTTTCTGGCGCATCGGATGAGAGATGCCTGAGATAATCTTGTGATGTTTTTGATGGTCTGGATGGGGTGCAGAAATAGCGGATGAGGTCTTTGCCTTCTTTCATCTTCTGCTCTTTCAGACCTAATACGGCCCCCACGCCTTCGAGCGAAAGCGGCAGGCCCATCGTCGCAGACCAGATCATAGAACAGCGCCAAGACGCGGGATTCAGGAATCTGGCACATTCTCTTGAAAGCGGATGCCGATCAAGAAAGGGATCAAGCGAAATACCAAGTCCCGCCAGATAGCGCGACAGGCATACCCGCTCAAAGGCGGCATTGAATGCCCACTTTGTGACGGTATCGTCAGTCAGGGCAGAAAGCACCTCGCTTGGGATTTCCTCTCCGGAAGCCAGATCGATGACCTCGACCGGTGCGCCGTCCGCACTGTAGCCGAACAGCAGAATCTCGAAGTCCGGGCTTTCCGCATATTTGTAAAGACCTGCCTTGGCGAGATTTACCGAAGAATAGGTCTCGATGTCTATCGATAGTGTTTTCATACGTATGTCCTCATACAGAAGAGGGCGATAGACTGCTCTGCCGCCCTATTCATGGTTAACGCAGGTTTTTCATGCGCAGTTCGTGCGCTTCTTGCTCGCGCTTCTCCGCACGACGTTTGCGTCTTTCTTCCTCGCGGTTGTAGACATAGGTCTGCATTTCCACGATAACCAGAGAAGCCCCGAAAAGACAGAAAAGAAAGAGTGACAAAACGAGAAGAATGGCCTGAAAGTACTCCATGGATTGTCCTCCTTTAGCTCAAAAAGTCGTCATCGTCATCCGTAGCGAAGTCGTCCGCTGCGCTCATGCGTCCACCCAGCGGCTCGCCGTCACGAATCTTCTGCAGGTTGTTCAGCCCACAGGCGATGCCTTTGTTGCCGTTGGAATTGAAGGCATAGAAGGTGATGGATGCGCGTCCGTATACACCGGAATAGACCTCGGAGCTGTCGATGATTTCGTTTCGGTCGGCATCTACAATGCCCGGTTTGGTAGCCGAGTTGGCGTTCAGGAAGTAGCTATTCTGGTAAGCTTCGTCGTCCGGGCGTTCCGTATCGCCATCGCGAAGCGGTGTCTTGATGACCGAGAGGGCCGGAACACTTCTGCCGTTCCCCTTGAGCTTCGCCTCACCTTCCTTGTAGGCTGCCTCGATGGCCGCTTTGATTTTGTTCACGGTGACGGTGTCAGTTTTTGGAATGATGAGGCTCACACTGTACTTTGGCGTGCCGCCGTTGATGGATTTCGGCTGCCAGACATTTGCGTAGCTCCAGCGCGTATCCGGACCAGTGATGACCTTCATCGGGTTCTTGTACGTATTTTTCTTAGTCATTGTCGTTCTCCTCCTTAAAGTCTTGATTTGCCGTTTGCATGGCTGGACGTTTGTCGCTTTCCGGTACGAGCGAGGGCTTTCCCTGCGGCTTTTCGATGAGCGAACCGAGGAGTTCCTCGAAGCGCTTCTTGCTTAACAGTTTCTGCATTGCGATGATGCCAAGGAGCTTCTTCTCATAGGGATCGAAGCCTGCATCGATGACTGTCTGTGCCACGGCCTCCTCATTTAAGTAGCGGCGGTTGGATCGTCCTTCCACCAGCTTGAAGCCATGCCAGACTTTGCCGGAAAGAGCTCGCGATAGGGCATAGTCCTTGAGATCAGCGGCCCAGCTCGTGAGGTCGTCTAACATCGGCAGAATGGCTTCGATGTCCGCATCCGAGAGCGTCGGTGGCATCTCAAAGTCGAACTTCGCCAGTGCGAGATTCGCTTCAGCCCGTGCTCGGCAGTCCACCTTTGCCTTACAGAAGCGGCACCAGTCACCGGCGGCATAGTCGCCCTTGCCTTCGAAGGCAAGATGCGCCTTTGGCTTGAGCTCCTTCTCCGCCCAGTCGTAGAGCGTCTTGACGGAGAGCCGAAAGCTTGAGATGTTGTCTCGTCTCGGTTGGAAGATGGTCATGATGACCTTCTCGATGTCGTAGAGCGCGTCCATCATGGAGAGAGCTCCCAACGCGTAACACATCATCTGCGGATTGTTCTCCGCCTCGACCAGCACGCCTTGACCGTATTTGAAGTCGATCACGGTAAGCACCTTGTCGGCGACGATGACGCAGTCTGCTGTGCCGAATCCCTGCGGTACCCAGCGGGAGAAATCCACCTGTTGCTCGATAAGGACGACCGGATCCGCCGTGCCTTTCTTGGCTGCTTCCAGCTGCTCCAGCGCATAGCCTGCATAGGCATCCGATGATGCATCCATCTCCTCGTTGAAGTAGGTCAGGTCTTCTGTTGGATCGTCTGCCTTTCTGCCGAGCGCGGTTTTCAGCTTATACTCGCAGAGGCTATGAGCATCGGTCCCCACGGCGGCATAGGTGCTGCTTTCGTCCTTGTAGGAAGAAGCCAGCTTTGCCGAAGGCGGACAGGCCATCCAGCGATAGGCGCTGGAGGCGGAAAGTAAGGCGTGCTTATTCGGCATGGAGCACCTCCGCATCGGCAAGAAGCGCCGCGTAGTGGATTGGCTCCACATCCGAGAGCCTTTCCGCACCGTACTTTTGAATCAGCGCCCGCACCTCGTCGGTGAGTCCGGCTCTGGCTTTTTGGGCCAGCACCTTGCGGACATCTTCCAGCTTGAGCGCCGGCTTCTCTGGTTCCGGCTTTGGTGTCGGCTGCGGTGCAGGAGCGTTACCTCTCTCGTCCGTGCTGCCAAAGAATAGTTCATTTAGCTCGTTGGCGAGATCATTCAGCTTCTCACTGCATGCCCGAAGCTCTTCCACAATAGCGGCAGCTCTTTTCACTTGTCCCATAGGGTTGTCCTCCTTCCTCGGCTTGGCTGATGGATAGCAATTTCAGATTTCTCGCCAATCTCGCAGATACGCGGCTTATAGCGTTGAGAAGTTGAATTTCCTCGCTGCGTGTTTTGGATTTGGCATTTCTGCTATCTGAGTGGTATTCGTGCATTCTTTCACCTCACTTTCCGGGCCTTGTTTTGCCCTTCACATTCCTCTGGAGAAGCAGCATCGATTTGAGCGGGGTAAAACGAAAAAATCTGCCACTACTTTGAACAGGTAGTGGCAGACAATGTGTTTATTTGTTCCTTTCGGCTTTAAACTCATCTCGGAATTTCTTCATCTCGTCCGCAAAGGTGCGTTGCTTACGGCCGAGCAATTTCGCTACTTTGCGGTCAGAAATTCCATCGGGATGATCCATCCAGATTTCAATAATTCGGTCAGCTTCGGAGTCAATTTCATGTAGCCGGACAAAAAGGTGATCAAGAAGATCGTAATCGGTTATGATTTCTTCTGGCGTTGGGGTATGGTCCGAGACGTAATCGGACAGGGTGCCTTCTCCATCAGGGAGAGGCATATCCAGAGATACGGTTTTTACGATACGAAATTCGCAATAAGGACAATTTCCGTCACACAGCCAAAATTTAGGGCGCGGACAGGAGCATTCACCGTGATATTGTCTGCGTTTTCTAAGTGCAGTGCGCCAACGGTCATAATCTCGGTATTGTTTGTCAGAAACTTCAAACCAAATATGGGTGTTTTTGTCATAGATTTTTTTGCTCAGATTGTCATTATTTTGCATAAGATACGGGCCTCCTTAGCCCCACAACCGCTGATTGGTGTGGAGAAGCGGAGAGCCCGTATGGGTGCCAGCGGAAAAATGGACGCAAGAATCCCACCCGTCGCGGGAGAACAATGTCTCCGCTTCAAGTTGCGTCCAGCTGTTCGCGTGCTGGTCGTATTTATTTGTCGGTTTCACTGCTGTGGCGAACAGTCCCTTTCTGTGCACTCGGGACGATCACATGAGTGAACCGGAGCGGTTTAACGTCATGCTCGGGACAGAATCAGCGATCAGAATAGGAAAATGTTCTTTGCATTCACAAATCGTTTATAAGCGAAAGAACGAATACGATCATAAATCGCTAAAATCTGTGATATAATTTCAAAGGGTTTCTCCATCAGCTGTGCTGATTTTCTTTATTGTACGGAAAGTGCCTTTTTCGGTTATGACCGCTGATGACTGCGGTTTGACCTAAAAGGTCAAAAGGAGGTAGAGCCGAAGTGTATTTTCATGAAATCGCTGGCGAGCTAAAAACATATATGGACCCGACCAGACGCGGAGGTGATTTTGTCATTGCTCTGGTTGGTGAAGTATTGCGCGACCCTATGACTGAGGAAGAACAGCAGATGGACCTACAGCATGAGTTCAATCCGCTTGCAAACCGGATATCGATCAATATGCTTGACCAGATTTTCGAAGGGAAAAAGTTTATTTCAAAGGCTCGTGCTTGCTTGATTTGTAGTAGATATGATGGTCAGGAGTTTGCTGACGTGATAGATAATCTTTACGATGCAAATAAGGAACACTTACAGACATTCCTTGATAACCGAGGAATTAGTGTTGCTATAGAAGAGCTTGGATCGGCAGTTCAGGACGTTTTACATCAGATTTTTCATGGACTCGCTAAGGGATACCATGATGTGGATATAGAACTTACAATCCATGATCCGAAGCCAAGCATAAAAAACCTCGCAGGAAATCGAATCTACTGCGAGGACGGTAAATTATATATTGATGGTGACGTCATAGAGCTTCCAATTAAGCTGAGTGACGCGCAGATTTACGACTTTGAAGCGGGATATATTTCAGCCCTGTGTGATGCATACGCAGAAGCGTTGTCCCGTGATTCCGTAACTGTTGATGACATTCCATTCTTGCCGCAGAAATACCGGCACAATTTTTATGATCAGCGCAAGGCCTATTTAAGCGCAAAGAGTATCCAACGCTCCATCAGCGAGGTCTATGACGATGGCGAGAATCAGTTCGACATCCTCAAGGAAGACGCATACGGTGGAATAAAGATCACCTACTACGACGATTACGACAATGGGTATCGCAGATTGCTGGAAGTCTTAAAGAAGATATCGGACGTCCAGCTGGCCAAGTCAAGGCTCATGATGATTAGAAACTTGATCGGAAATCTGGAAAGGCTGGGCATTGTTCATATCCTCGTGAACGACCAGACGATTAAGTCGTGGGTGGATCCTTATGAGGAGTAAAGTATTCAATACGCCATTTGAGAATATGCTGCGCATCCTGCTCCTTGCGGATACAATAAATAAGCCCATGAATGTGGACAGATTCGTAGCCTTGGACTTTATCTGCATCTTTGGAGAAAAGTGCCGAGTGCTTGATAAGAATCTCCACGGCGACAACGAATTCGGCTTTTCCGAATTTGCCACCAAACGAGAGCGCATCGCCGAGGCTGTAAAGATCGCTGTCAAGAATGATTTTCTGACAGTAAAAGCCACGGACGCGGGCTTCACTTATGGAATGAACAATCGGGGCAAGGCAATAGTTTCAGGTGTACAGTCCCCTTATGCGCATTCTTATATTGTGGGAGCGAAAATTGTAAACAGTCGCTTTGCCAGATATACAGACGATGAAATACTGCAATATATTAGCGACTTGTCATCTGAGGCGGAGGAGGGGTAATTGTGCAGACTTTTATGATTAAGAGGCTCCGCGTGTCCGGTTGTGGCAAAATCGATGGCATCGTGGAGTTTACCGATGGCCTAAATCTCATCCAAGGCAGATCTAATACGGGCAAGACTTGGATACTCAGATGCATTAACTATTTATTTGGAAACGATAAGCGTCCTTATACACCTGCGACCGGATACACAGATATAGAGGGCATTTTCCTGACCGAACGGTTCGGTGAGATTACGTTAACTCGCAAGCTGGATGAGAACACCGTCACGGTTACCTCCAACAACAAGGAGGTCGAAAATGGAGAGTATGCAACCAGCTACCAGCAGTCGAGCTTGCAATATCTGAATGATCTTTGGCTGCGCATTCTCGGTCTGGACGAGACCATTAAAGTACCTAAGAATGCCTGTTATGGCAGAGAGCGGATGTCATGGAGGAACGTGGCCGGTGTCTTCTATGTAGATGAGGACGAGATCTCCAGTTCATCATCAATTGTCATTAAGGGCAATTCGTACGAAGATACCCCGCTTCTTGCGTCATTGCTCTTCCTACTTACTGGCGATTACAAGAAAGGTGTTGCCGAAATCCTGAATGCCAAGCAGGCAACTGCGCGTACACAGGGCATCCTCGAATATATTGAGGAGAGGACGAATGCTCTGAAACAGCAACGCGTTAGCTACATCATGCAGCTCGAAAAACTTGCCGATCATGATATTGAATATGAGATTCAGTCGTTAAGCGATAACATTCAAGAAGTACAGCAGGAAATCCATGAGCTTGTTGAAGAAAATAAAGCAATTGCGCAACAGCTTTCTGGCTATGAACAAAGGGATGCAAATTGCAGTGTATTGTTGGGCAGATACGAGTCCCTTATAAGCCAGTACAAGGCAGACCTTCAGAGGTTGGACTTCATTTCGAAGGGAGAAAAGGCGGTCCAAGAACTGCCCTCCAACGACGTATGCCCGTTCTGCGGCGGCGAAGTTCACCCGGAAGAGAACGTCAACTTCATGGAGGCTATCAACGCAGAGATAAAGCGAATCGCATCGGAGCTCACGGTGATTGCGGCCACGGTGAAGAGTGTTGAGGAAGAGCAAGCTGGTATTCGTGCAAACATTGTGGAGTTCGAAACGCGAAGAAGCGATTTAACCAGTGCACTCGTAAAAAAGAACAACACAGTTCAGAATTACAAGGTAAGCCTCCAACGCTACCGTGACTACACAACTCTGCAAAATGGGATTGATTTCGTGAATGGTCAACTTGAGGAACTTGGAAAAAAGAGAATCGACGAACTGAAACCAAAGAAGAATCTTCCTCAATACCATCCAAAGAAGGAATTTGAGGAGGAGGTCGGCACGAATTTTACTAACTTGTTGAACAAGATTCTCAAAGAATGCCACTACCGTCTGTTCGGTTACACGAGCTGGGATTTCAAACATTTCGATATTCACGTAGATGGCGAACCGAAATCTGACGATCAGGGGCAAGGTTTTAGATCATTCCTCAACTCCGTAGTGGCAATTATGCTGTACGAATACTTCAACAAAGACGATGTCTACATTAGGCCGGGATTCCTCATGATCGATACTCCACTGTTAGGCCTTGACGAAGACAACGAGGGTCTTGACAAAGAAACCATTAGAAGTGGCCTATATGAGTATTTTTTGAATCATCAGGGCGAGGGGCAAATGATTGTCGTCGACAACTTGAATGCTGTTCCAAATATCGATTTCGAAGCTTATGGAATCAATGTAGTCACCTACCACAAGAACGAAAGGGATGGCCACATCTACGGATTCATGCCGAGCTGGAGAAAAGACATACCGAAGGAGTCACGATGAAACTTTCGTATAAAAAACTATGGGTAATGCTTGTTGAGCGAGATATGAAGAAGACCGAGTTCGCAAAGAAGGCGAAGATTAGCTCTGCCTCCCTTGCCAAGCTCGGAAAAGGAGCCAATATCACGACGAATGTTCTTGTGAGCATTTGTGAAACATTAAAGTGTGATATTGGAGACATCTGTGAGATTGTTCCAGATGACGTGGTTTAACCCTCACAAAATCTAGTGTTTTATGTGGGTTTTAAGATGACCTCATTCAACATTAAGCGTATGATAACCCGGACAACCGAGATCTAAATAAACCACATATTTGTTTTGATTATTATTGACACAATCAATTGCATATATGCCAAGTGATATTGAAAAAGATTATGGATCAGTGGATAAAACATTATTTGTGCCACTGATCCACTCTATTCGGAATTGACCAAAGAATTGCTCAGTATATTCGACTTGGAGCAACTAAATGATTATTATTGTTTCTTACGGCGAATAGTCCATAGCACAATAATATACACTATAAACACGATTATCCAAAACCAAGCGGATATGCCATAAATAAGAGTGCCATTCAAAATGTTTTTTATAATTACCACAAGAATGACTATTGATATCAGAATATCTCCGAAATGAAATGGCGATGTTTTTTTCATTTGATTCTCTTTCTACAGTTTAACCATGAGAGTATAAATACCACTACCCCAGCAATAAGAGTTATATATGGTAGACTTTCAAATGGAATATCTGGGATATGTAGATATTTACCGCTCCCAATCATTTTTGTAAGCAGTAGAGCTACTAGCATCAATAACATGGATGATCTAGCAATGGAATATGAATATCTATAAAATAGATATAGGAATAGAGCTATATATGCTAGCTGGAAGCTGCCCATCAAAATAAATATTTCTGATGAAAAGGACACTCGATAAGGAGTGATAGTTGCAATTAGCAAATTTGAAATTAAATATAAACAGGAGCCTTCAGCGATTGTAAATAGGGACAAAACAAACTTACTATCAACAATCTGTCCAGCATAATGCGGTAAAGTTTTAATCCAGTTTTTGGATTCACCCTTCTCATCAAAAAAACATGATTGGCCTATAATATAAGTGAAGCAAGTCGCTAAACAAATATATAGTCCCATAAAAGAATAGTTGCCGCGATCTAGGCATAGTAAACCAGTTGCAGACATTGAAACAACTAATGCTATAAAATGGTACCATTTAGTAGTAGATAAATCTTTTCTAACATAATTAATCATGAAATCACCTCAATTGTTTAGCATTGATAGCATATTCTCAAAAGATAATGGTTTAAAATGATCAGAGTATCTAATTAAATTAGAAGAATCTAGTGATTTACACCATATAACGAGCTCAGCTCCTTTAGATAATAGTGTAACATAATTATCTAAATTGAGCGTGCTCAGAGCTTGTTCCTCAACGAGGAAGCAGGAATGCTCAATTCCTTGTGCAGGCAAATCAAACTTTAATTTTCCATTACTGATAAATATGATTCTATCAGAAATTTTTAAAATATCTTCAGTAATATGAGTCGATAATATAGTGGATACACCTTCCTCTTTTTTCTCTTTCAATAGTTCAAGAAATTCAGTTCGAATAAAGGGGTCTAGTCCGCTTGTCGGTTCGTCAAGTATAAGTAGTTTTGCATGGTGGGCTAATGCAAAGGATATGTAAAATTTCATTTTCATTCCTTTTGATAATTGAGCGATTTTCTTATTATGATCTGTTATGAGAAACCTATGCATTAGCTTTTCATACATGTTTTGATCCCATGACTTATAGAAATATTTAAATATGTTAACAAACTGTTTTAATGATAACATATCGTATATACTAGTATCTTCTGAAACGTAAGCAATATTAGATTTAAAGTGAACGGGATCGAGGTTGATATCATAGTCAAGCAAACTAATAGAACCTTTGTTTGTACTTAATTGTCCAGTGATACATTTTAAAGTAGTGGTTTTACCAGCACCATTTTGCCCAATGAACCCAATTATTTCTCCAGCATTCATTTCAAAGGAAATTTCTTTTAGGTCAAAATGGTTATAGCTAAATGAAATATTCTTGACAGAAAGAAGATTATGCTTCATGGTAATACTCCTCCTTGTTTTTTATCATCTGCAGCATAGGATCCTTGATTGTTCCGAATTCACTTAACTCCGAGGATTCAGGGCAAGGCCAATCTGGGTGCACTTCCTTAATCCCTGAAATAACACTACAAACAGCCACTAGAGTCAAGTCTGAGGATAATGGAAGTAACTTTGACTCAGTGAGCGCACCCATTGTAGGTTCTCCTATAATAATACAGTTATTGCTTTTCGTTCTAAAATAATTAGCAATTCCGGGCTTTTGAAATTTAGTGCACACTTGGCTGTCGTATTATAACGTCGCTCATGCTTTTTTACCTGCTCTATAAGATTTTTTTTTGTGAAGACGTATCGACTATAAAGAATTTTCCCATCCTCTCGGTGACTTCGTTCCACCTTTCCGTTCTGCCAGGGTGAATAGGGCCTTAGAGATCCCAACACAAAGTTCTTGGATCCCGCATGCAAATCTGCTGTATATTTGCGCGAAATTGCCAAAAGGTTAATCGCTGGATTGGCCGACAAAATTCCAAACTTGCAGGAGCGCTGCAACTGGATCTTCAAGAATCAGCTATATGGCATTGCCATAACGGAACTCACCTCGCCACTGTCGAGAAGGTCGGTCTACTGCTCAAAGCATGCCAATAGCCCATTTCCGATTACGCCATTCGACGATGTTCAGGGAAACATACTGTTTCACGAGATTAAACATACCTGGGACAAAAACGACAAAAAGGGGCACTGCATATACTGTGGAATTAGCTTCAATAACAGTTTGAATGACATCAGTAGAGAAGGTATGGAAAGTCATGCTTATGAATTTATTCATACCTTGCATCCGGAGGAAATATTCGAAATGAAGTTTGAAATTATACTGTCCTTTTTACACCAACATTGTTGATAAGACTTCGGAAAACGTTTATTATAGAAGAGACATAAGTGTTGACTTCGGATTTTTGAATAATCTGGATCAATATGTTGCAGGTCAATAGGCGTGAAGTTGAACAAATATGAGCTGGAATGTCGTGTGATTGGCGATTAAGGAGGATGTAATGAAAAATGTAAAACGACTTGTCGTAGCAACAATGTTGATGCTTTCCTTATTTTTAGGTGCTGAGGGTGTCAAGGCCGCAGGATGTGGCACATATTACATCTACAGTACATCTACTCCGAAATGCTACTCAGAACACTGTGGTATTTGGGACGCTACCGCACTTGTACAATATCAGTATAAAAAGCGCAAATGCGTCCGAAATGATAATACTGACTATTGGCAATACCAGACGGACCGTGTTCACATTGATTGCGGCTGCTAGATTGAATTTGTTTCACATTGAGTTCAGCTAAATGGACATGACATTCCAGCTCATATCTGCTCAACGAAACTTGTAAACATCTAAATATTATGGGAGGCGTTAAAATGAGTAAAAAACATTCCAGAAACTGGATGATCACAAGTATTCTACTTCTTTGCCTCTGCACTCTGACCGCCTGCATGCATCAACAACCTGCGGAAGAGGAAATCAACGAATCTTTCTACAAGATGTCCCGGACTTCATCCCAACTCTATGAAACAAAAGAGATTGGCTTAAAATCTATGGGAATTCAAAGAGCTTCTGGTTTATTGTACTTCAAGGATCATATCTATTTATCCGACAGCAGCCAAAGCGAAATCAAAGTTTTTAATCAGCAATGGAATCTGGTCGAAAGCATACATTCGAAAAAAATAGCTTCTCCATCTCTACTTGCGGCTTATGGAGATCGTTTGGCCATCCTGGATAAGGCCACATCACAAATTGTCCTGTTTGACATTCCATCGAAAAAAGAACAAAGCGTGATTATCTTGCCATCGATTGATTCGGACTCGAACTATGCAGACATGGAAATGTCAAAAAATGATTTGCTGATCACCTATCACACGCCTGCCTTCGAAGATGCCAATGTGTTGAGAATAGACCTTTCAACACGAAAGAATAAAAAAATACAGGAGAAATTTAACGGCTTTGTTGGAACAACAAATGGAAAATTTTATCTGGTTAATTCCCTTGTTGCTTTTCAGGAATCCGATCGGGAAGGCTTCCGAAGTGGGAAAAACAGTTTGTGGACGCTGGAGGATTCTAAACCGAAGGCGATTGGGAATCTCATTGAGGGAAGTGCCCCAGGAGATTTTTTATGGAATGGAGAGATATTGTTTCAATACACCAGTGGCTGGTCCAGTATCGATCGTTATGATAAAAGTTTCAACTACATGGATTCCATCGCCGTTTTTGATCAGTCGGATATTCAATCTCTGCTAAAAGGCAATGAGCAACAAATGTACTTGCTCATGCCCAATGAACAAAAGCTCTTTGAGGTCCATAAAAAATGAGCATTCTATATAGTCTTTCGATACGTTGGAAAGCAAAAATAAAAAGAGCTCGATTACTCTTGTTAGAGGTATTATCCCTCTCTGTGGTCTTTTACTTTGCACTCATGTTTGTTTGCAAACTGGTTGATACACATGGAGACATCGCTTATTATCGTTCACGAACCAATGTTGGTGAGGTGGTCTATCAGCTGGAGAAAGCTCCAGAAGCAAAGATTTCTGATGTGGACTTTACGCTGTATCAAAAAGCGGATCAGTATGTGACTGTTCATTCGAAAACATATAAAGCTCAGGTGATAGGAATCGATCAAAATTTTTCAAGTTTTTATCATGATCACCTGTTTCAAAATATAGTGAAGAAAAAGGCCCTCTCCCATTCAGATGCGATTCTTTCTCAGTCAGTCGCACGAGAAATGAGTGCAAAAGAAGGGGACACGTTGACACTGAATCATCAGGTTTTGAAAATCATTGGTATTACCGATGATCCCTGGTGGAAAGGCAAAGTTGCGGTTTCCTTCTCTATTCTGTCCGCCTCTGAGCTTGCCCAACCGAAATCTTTGTATTTGACAATCCGTCGAGAAAATGTCGAACTCGTTGAAAACCAATTATCTGTTCTGGATCAAACGGATCTGGCGCAGTCATTACAAAATGAAATAAACAGCTTACGTGCTTTTCAGCGTTTTCTACTCAGCTTTTCTGCTGTTTTCTTTTTGATTGCTGGATGTAATTTGATGCTCATTCTGAGGACTCGGTTTCGTAGGGAAAGGGGTCTGCATCAGATATTGTATCTTTGTGGTGAAACGCGCGGGACTTACTATCTTGCCTCCATGATTGATGGTCTGACGATGTGCATCTCATCTGATTTCATCGCCCTCCTGATTTATCTGTTGATGCGCCCATTTGTACCATCATTTTTTTACTTTGCGCTGACTCCCACCATTTATGGATTGGAAATGCTGATGGTTGCAATGATATCCATCATCATCACGCTCATCTTCAGTCATGAACAGGCAGTGTATATCCGTATGAATGAGAGGAAAACTCATGCTGTATGATCTGTCAATCATCTGGTTTCACCTGAAAAAGAATATCTTTTTTTATCTATTTTTGATTTGTGAGCTGGTGCTGTGCTTCTCGATGATATTAATAGGGATGGACGAAAATCAGACGTTTCATGATCGCCAACAGATTTATCGCGCGTATCAGGAAAAAGATCTGATCTCATTAACAAATGATTCCTGGTTTATGGAGAAATTAGACCTAAGCACGAATCAGAAAGTATTGACCAAGAAAGGTATTCTGTTGGGACAAGTATATCCCATCGAATGGACCAACAATCGAGGGTCTATAGATAGTGCGCAGGTGCTTGTTGCTAATGATCGGTTTTTCAGACAGTATTTTCATCAAGTTCCCAAACAGGGATTGGCTTATTGTAGCTTGGCCCTCAGAAATAAGTTGAAGGAGGCGAGACAATTTTTAGATTCACAGACTCGGTGGCTAACGCAAGAGATCCTTCAATGGAACGAGCAAAAGTGGAGCGTTCATTCAATCAACGAGTTGAATCCGAAGACCACTTTGAAAAGCATTCCAACATCGCCTTTTGAAAGTGGAGATCTTTCAATGGAACGAACCGTATTTGTTCTAATGCCCGATCGCATGCAAATACAACCAATATTTGGCTTTATTAAGGTTCCTAGAGAACAAATGACTTCCAGGCTCTTGGCGGAGGTGTCCACGATGGTCGAAGAGAAGCTGCATGCTTCTGATCTTCACGCGGATTTTGAGAAGGGCGCTAACAGTCAATCTGCTTTCGTTCGTCTGTTCGGATGGATTGCATGGATTGCTCTTCTTGTCATCGATTTTGGAACCAGCGCAGTAATTTTACTTTTTATGAACCAGCGGCATAAAATGCTCCGAATTCAGCATATTTTTGGAGCGACGAGGTTGAGATTACGCCTGCAACTATTTATTGAATTGTGCATTGTTATGGTCGTCTCCTTTATTGTTGCTTTATTTTTACGATGGATATCGGAGCCAGCCTTTTCAAGCGTTTATTACCTTATTCATCCAAGCGTTATCGCAACGCTAAGTGGCATCATGTTGGCATTTGTGTTATGTATTTTCATCACACTGTTCTCCAGCACTAATATGGAATGGAAAAGAAAGTGAGGAGGAGATGACTCCCATCATTCAATTAAAAGATATCAACAAGCGTGTTCAGGACGGCACGCAATCCTTGCAAATATTGAAGGACTGCTCCATAACCATTCAGCAGGGAGAAATGGTTGCCATATTAGGCCGATCGGGCGCAGGTAAGACAACGCTGCTTAATTTGATGGCAATGCTGGATAATGATTATCAAGGAGATTATTATTTTGATCAAATGAATGCGCATGCTAAAACAGACGCAGAGCGTTTTTCACTTCGAACAAAATTCATCGGCTACATTTTTCAGGATTTTCAACTGATTGAGGAATTTACTGTGCTTCAAAACGTAGAGATGCCACTTGGATATCAGGGTGTTCCGCGAAAAGTGCGCATTCAACGTTCCTTGAAAGCCATCGAAGATGTTGGCCTGGGTAGGCGCGGAGATAGCAACGTTGGCACTCTTTCGGGTGGTGAACGGCAACGAGTATGCATTGCACGAGCGTTGGTACATCAGCCCAAAATCATTTTAGCCGATGAGCCAACGGGCAGTCTGGATCCTAAAACGAGTGAAGAAGTTATGACCCTGCTGATAGATCTGAACAGGGCATTCAACATTACGGAGGTGATTGTCACGCATGATGAGGTGGTGGCGAACCGATGCTCCCGTATTTATACGTTAAAAAATGGAGGAATTCATTATGAAAGGTAAAAAACTAATTGTCGCCACACTGTTTTTCATTGGTGCTGTGATAGCTGTACTAGTTTGGAGAATGCCAAAAAGTGATTATCAAAGACATGTGGCTAAATTTCATAAGGTCAATACTGCTAAGGTTGAAAACATGCTGTCTGATTCGAATGATTTTCTCTTGTATATTGGGCGAGAAACCTGCCCGACGTGCGTCGAATTTGTTCCCGCTCTCGCGAAGGTGTCAAATGAAAAGCGTATTCCGGTCTATTATCTGGACTCTTCGAATACCGAAAAAGATGCCAAATTAAAAAACTTTCGGGACAAATATAACATCATGTTTGTCCCTTCTCTGATGGTATATGTCAATGGAGAAGTCAGATTTCCAGAAGTCGCGACTGACCCTGCAAAATTGAGTCAGTCTTTGATCGCGATCGGTTTCTTAAACGATTGATCGAGAGTGTAAGATTAATTGTGTTTTCTGGAAACGAGGTGATATAGAAAAAGGATCCTCGAACCTATAGAATTTTGTTACCACAACAAAAGAAAAGGGAAACGAGGAATCCATATGAATGATTTTACCACAGACGCTAAGATGGCTCAAACAAACAAGATCAGTTTGACGGAAATTGTGCACCAGCATGTTGAGGATGCTGTCAACCAGCTTCTCGAGAATGAACTCACCGTCTTCCTAGATCACGAAAAGTGGGATATCGTGGCCAAGAATACGGATGATTGCCGGAATGGCTATTATGAATGCACCATCAATTCTGAGTATGGTCCGCTTCATTTGCGCGTGCCAAGAGATCTAATGGGCGATTTTGAGCCGCATACAGTGCGAAAGCGCGCTCGCTCCACCGATGGCCTGGAGCAGACGATTATTCAGCTATACCAAAAGGGTATCACGACTCGAGAAATCTCTGAGAAATGGGCACCAACCTATCCGCAGTTGAAAAAAGTATTCGAACGTCGCGACAACCTGTTCTCCTTTTTGGCCTTTCTGGAATCCGTTCGCCGGAGCCTGTATACAAACAATTTAGCCGAGAGCCTGAACAAAGGGCTCAAACGCATGATTAAAGTCAAAGAACAGTTTCCGACGGAAGATACGCTGGAGCGCGGTGTTTGTTAG

Protein sequences of DBSCAN-SWA_1

>NZ_LT632322|348035:424895|402236_403601_-|WP_071705075.1|DBSCAN-SWA
MQYRAHDYQRFVTTYIEEHTVCAVLLDMGLGKTVITLTALSDLLFDAFTAHRILVIAPLRVARDTWPAEIKKWNHLKHLTFAVAVGTIKERRTALAKKADITIINRENIDWLIRESGYPFDFDTVVVDELSSFKNHKSKRFKALMQVRPKVKRIIGLTGTPAANGLMNLWAEYKLLDMGKRLGRFIGGYRERYFLPDARNGMVIYSYKPKLDAENAIYRAIGDITISMKADEHLKMPELISTSVPVSMNDLETELYEKMKKELVLSLEGGDVTASNAAVLTGKLSQMANGAIYGDDGDTITIHDRKLNALEDIIEAANGKPLLVAYWFAHDLERIQQRLEKLKVRHQKIDSAKSIADWNAGKLEVGLIHPASAGHGLNLQDGGSTLVWFGLTWSLELYQQTNARLFRQGQKSKTVVLCHIVTTSTIDEEILAALKHKDKTQSALIAAVKAQLKA
>NZ_LT632322|348035:424895|372253_372649_-|WP_083428143.1|DBSCAN-SWA
MKDGKIAIHEEEACALKSLFENYLSGMSLKASAQSVGITFTHSVIRRLLENPIYAGSEGYPALISEEWLKQAHELRLSRAKNLGKEKLRHKRRPTFYVKTRFYMDEIDCGDRSALEQAVYVYNQIREVEDE
>NZ_LT632322|348035:424895|366164_366329_+|WP_157885047.1|DBSCAN-SWA
MLWAKHRHRNRAKSRANRAKSRANRAKSRANRAKSRANRAKSRANRASRQRNRK
>NZ_LT632322|348035:424895|392635_393286_-|WP_071705066.1|DBSCAN-SWA
MERHYHLEGKERRPLVSALEKLTGEKAKYEGIPTYAYTIGSFTVDRFGTLLSDDEERMEKIAEALAFEGFQAEEDADLFTISLPREGFSESAIYRITMVVASKKSVIQHALDISATPIKITKEKIHFPWFDRIPSADEVKAYTTFIALLAKHAKEAKRITGKDHEVENEKYYFRCFLLRIGMIGAEYKETRKVLLKNLQGSSSFKFREPDEEAKNA
>NZ_LT632322|348035:424895|391794_392151_-|WP_071705063.1|DBSCAN-SWA
MKHIEILDQAKEQKIYYKEIGVNPTFGTAYLTSLEAGNDVPDFADVIWNDDIEEILRDCRRFGITEFTISSAFSGIIETIDKFVELGCQLNGLTKVRSRFNDWRTGEKEIKPAFKLGL
>NZ_LT632322|348035:424895|419620_419884_+|WP_071705092.1|DBSCAN-SWA
MKNVKRLVVATMLMLSLFLGAEGVKAAGCGTYYIYSTSTPKCYSEHCGIWDATALVQYQYKKRKCVRNDNTDYWQYQTDRVHIDCGC
>NZ_LT632322|348035:424895|350860_351541_-|WP_097677427.1|DBSCAN-SWA
MQLLRRFAAWMNISVLDLFLMVLGNLTMAFAIYNIHVPSRITEGGVLGSIVLLNKVFGLDPAILSIVLDFSLYGLGILLLERGFLKKAVFSTLAYAGSWTLFAAIGPVLPSLANAPHLAAIVGGLLLGAGCGLVVTRGGAAGGDDCFALILKKRTSLSLSSAYFISDAVVLGLSFFIYLPAQNLLWSFLTTLISSFVVGQFELRLPKPGTLAMPMKQQADASNMSA
>NZ_LT632322|348035:424895|398096_398480_-|WP_071705071.1|DBSCAN-SWA
MPYKPKTPCSWSGCPKLTEGRFCQDHQKLYDKQYETYDRDRNAKRKYGRAWKRIRDCYIHTHPLCEECLKEHRYTKATEVHHRLPLSHGGTHEKRNLEALCHECHSRITAEMGDRWHKRKNNKSSDR
>NZ_LT632322|348035:424895|352606_353005_-|WP_147659358.1|DBSCAN-SWA
MSQNVLPPPSLTASVMVGVCVKWAFTTITCDFGDGGDLPKSRFHHHHLRLRRWWWFAKIALPPPSLAASAMVVVCQNRASTTITCDFGDGGDLPKSRFHHHHLRLWRWWWFAKIALPPPSLAASAMVVVCRK
>NZ_LT632322|348035:424895|374688_375627_-|WP_071705048.1|DBSCAN-SWA
MSKGIDVSKWNGSIDFNKVKADGIDFVIIRAGYGWDTSQKDRTFEQNYARAKAAGLHVGAYWYSYARSADNARSEAKVCKQIIAGKQFDYPIFFDLEESSQLSRGQAFCDSLIQAFCNEMEAGGYFAGFYTSASVARNILSKSIRKRYAFWCAQWANTNSFEGESGLWQYSSKGSVSGIAGNVDLDISYIDYPSLIRGGGFNGYAKGSTAPTAKPAPAPEKKTVETLADEVIKGLWGNGEERKRRLTASGYSYDAVQKKVNERLSVKPKKSINTLAREVIHGDWGNGNERKNRLTKAGYNYDAVQKRVNELL
>NZ_LT632322|348035:424895|421977_423102_+|WP_071705095.1|DBSCAN-SWA
MLYDLSIIWFHLKKNIFFYLFLICELVLCFSMILIGMDENQTFHDRQQIYRAYQEKDLISLTNDSWFMEKLDLSTNQKVLTKKGILLGQVYPIEWTNNRGSIDSAQVLVANDRFFRQYFHQVPKQGLAYCSLALRNKLKEARQFLDSQTRWLTQEILQWNEQKWSVHSINELNPKTTLKSIPTSPFESGDLSMERTVFVLMPDRMQIQPIFGFIKVPREQMTSRLLAEVSTMVEEKLHASDLHADFEKGANSQSAFVRLFGWIAWIALLVIDFGTSAVILLFMNQRHKMLRIQHIFGATRLRLRLQLFIELCIVMVVSFIVALFLRWISEPAFSSVYYLIHPSVIATLSGIMLAFVLCIFITLFSSTNMEWKRK
>NZ_LT632322|348035:424895|388311_389622_-|WP_071705061.1|portal|DBSCAN-SWA
MGIFSGLFKSRDKPENRTTGSSYAFYLGGSSSGKAVTERSAMQMTAVYACVRILSEAVAGLPLHLYRYKEDGGKEKALTHTLYRLLHDEPNPEMSSFVFRETLMTHLLLWGNAYAQVIRNGKGEVVALYPLMPNKMSVNRGSDGNLYYEYARQTEEAHTMKGSTVRLKPSDVLHIPGLGFDGLVGYSPIAMAKNAIGLAIATEEYGSKFFANGAAPSGVLEHPGTIKDPARIRDSWTATFGGSGNANKIAVLEEGMKYTPISISPEQAQFLETRKFQIDEIARIFRVPPHMVGDLEKSSFSNIEQQSLEFVTYTLDPWVVRWEQSIHRRLLNPEEKQDFFVKFNVEGLLRGDYQSRMSGYATARQNGWMSANDIRELENLDRIPKEEGGDLYLINGNMLPLSHAGAFANLEASGKEEQDSEEEILELESEPQQRRR
>NZ_LT632322|348035:424895|385360_385744_-|WP_071705058.1|DBSCAN-SWA
MTRKVSVDEMADQIHLALQEYAKVASDDMKRIVKSTATSVKKEIQQNAPQDSGDYKKSWATKTTRENANLLEVTVHSKDRYQLAHLLEKGHAKRGGGRTRAFPHIAPAEANGEEKLMSELERSLSDG
>NZ_LT632322|348035:424895|423779_424220_+|WP_071705096.1|DBSCAN-SWA
MKGKKLIVATLFFIGAVIAVLVWRMPKSDYQRHVAKFHKVNTAKVENMLSDSNDFLLYIGRETCPTCVEFVPALAKVSNEKRIPVYYLDSSNTEKDAKLKNFRDKYNIMFVPSLMVYVNGEVRFPEVATDPAKLSQSLIAIGFLND
>NZ_LT632322|348035:424895|368977_370423_+|WP_157885022.1|DBSCAN-SWA
MTKKKHPVVDVRIEELAYPDRASGVVLSTIAHDPVGEMLELPVDHSKREAVAPMRMKGGLPGQVWRCRVKRSHAGVREVMPLQLLAPSPMEHRPTCPQAGICGGCNYQTISVESELLLKSRQLRELYAPLGLSSAISLYRSPLLEGYRSKMEYTFGDSTPGGPLTLGLHRPGHFYDILPTPLCNIVPEDFNSLRKAVERFCREREWTFYHRAKKSGYLRHLVLRAALTTGELMVNLVTTSERTWTALDTTEFLRLLHSLSLSMRLVSVFHTTNDSVADVVQADALDLLEGRSYLEERLFDLSFHVGPFSFFQPNVMGAKNLYSKALDLAGDLRGKTVYDLYSGTGTLAQIAASRAQRVIGVEIVEEAVEKAREACQRNGLANVRFVASDVLAELTRLADIGDRPDVVLLDPPRQGIHPKAVAHLIAAAPERIVYISCNPTTQVHDLSLFTAGGYRVEQVVAFDQFPRTKHVETVCLMSRKD
>NZ_LT632322|348035:424895|406240_406642_-|WP_071705077.1|DBSCAN-SWA
MENLYKNNEGYADPTVYEAVFKPQRYPYMPLVYIASPYAGDVENNVKAARRYARFAIDHGFIPIVPHLLFPQFMSEKTERDLALFFGLVLIDKCTELWAFGEPTLGMGREIAYAKRHKRNVRYFDAAMQEVCR
>NZ_LT632322|348035:424895|394927_396196_-|WP_071705068.1|DBSCAN-SWA
MNTTKDLKLIPIDKLIPYVNNARTHSAEQINKLRSSLREFGFVNPVIIDEKYNVIAGHGRILAAKAEGLAEVPCVLADHLTEAQKKAYILADNRMALDAGWDEEMLRVEIEALQEQAYDLSFTGFDEKELAALFETDAEGTEDDFDIEAELKKPCFSKPGDIWHLGKHTVICGDATEKETYQNLLGEIKVNLVCTDAPYFVNLESKSGKIKNDDLSDKEAYAFLMKAFTNFKEAMTIDASIYEFYATMKTRVFYDAFEDAGFKVGAGLIWKKPRAPFMRTDWKFNMEPIIFGWRKDGKHIWYGDQKQTSVFEFGGIRDSKEDGFGHPSSKPVPLIAYLIKQCTQTNGLVLDGFLGSGSTLIASAELGRICYGIELEPKFVDVAVNRYVNFIQGETKDVFVLRNGEKFTYDEIVASLPEEDHA
>NZ_LT632322|348035:424895|385047_385368_-|WP_071705057.1|DBSCAN-SWA
MDEIMQMLSEMHVPFAYDHFEEGHAPDPPFLIFLTPESRNFAADGLVYFLVSVWNVELYTDKKEPEVEKAVEAVLSAHGLFFDKTEVYIDSEHLYEVLYSFELKGE
>NZ_LT632322|348035:424895|384092_384449_-|WP_071705055.1|DBSCAN-SWA
MIEKTILVSGKEVTFKSSAAIPRLYRAKFGRDIFKDLAKLEKSYSGKKAEDGGFPIEDLEIFENVAYIMALHADASIPSSIEEWLDGFEMFSIYEVLPEILSLWGANMKTEVASKKGK
>NZ_LT632322|348035:424895|396192_397344_-|WP_071705069.1|DBSCAN-SWA
MTQTIKSAESVRAGHPDKLCDQIADAVLDKVLTLDPEGRCACEAMATEGNIYVAGEISCKETLNIVSIVKDVLRRTGYSTNRIHIHVHIHAQSQDIAGGVDHALETRTSTDQALGAGDQGTVVGFATDETSELLPLPLVLSHRICQKLDGCMKEHTIDGLRPDGKAQVSIAYQDGKPARIKSIVVSAQHTRQKDLSKFAEEIREKVLIPAFASFPFDEETEIYINPSGRFVLGGHAADTGLTGRKLMVDTYGGLALHGGGAFSGKDPTKVDRSSAYMARAIARNVVMAGLAKKCQISISYAIGKAEPVALAIDTFGTGTASDERILSAIGETFDLRPQPIIETLSLMRPIYSETSVYGHFKNSSHATWEKLDKTAILREAVRG
>NZ_LT632322|348035:424895|401703_402168_-|WP_071705074.1|DBSCAN-SWA
MHITWKYLDKRAATIEALRDYHSMQFIIENTEDAIKERYERMMSISSPAYDGMPHVHDPQSGETRLANSLYQIDVLKERYRQAREYMDWFVPAWKALSDDERFCLEEFYWTEEYESRTDAIQTICERLHIERSSAYNKKNRAINHLKVNLYGKG
>NZ_LT632322|348035:424895|384445_385045_-|WP_071705056.1|tail|DBSCAN-SWA
MPEQNKVKYNIKNVYAAKLTETIAEDGASTFAYATPKRIPGAVSLSLDAEGESSPFYADGIVYFRTVTNNGYSGDLEIALIPEWFRTEILQETLDAKGVLVENSNAAESVKFALLFEFDGDIKAIRHVLYNCTASRPSIASETKEDTIEPGTETLSLTADPRSDGLVKAKTGDGTDATTYDGWYTAVYVPTNKTAGGAA
>NZ_LT632322|348035:424895|409893_410466_-|WP_071705081.1|DBSCAN-SWA
MTKKNTYKNPMKVITGPDTRWSYANVWQPKSINGGTPKYSVSLIIPKTDTVTVNKIKAAIEAAYKEGEAKLKGNGRSVPALSVIKTPLRDGDTERPDDEAYQNSYFLNANSATKPGIVDADRNEIIDSSEVYSGVYGRASITFYAFNSNGNKGIACGLNNLQKIRDGEPLGGRMSAADDFATDDDDDFLS
>NZ_LT632322|348035:424895|385740_386073_-|WP_071705059.1|head|DBSCAN-SWA
MDISLLNARVTFQKKSVTTDRYGNQIAEWTDFYSCAATISGEGGGETFVAASEEDRTDMAVTIRWCRKASEITMTGFRILFLGEPYDINRIDHLSFKKKALKFFCRKERP
>NZ_LT632322|348035:424895|378657_380355_-|WP_071705052.1|tail|DBSCAN-SWA
MSQFTVYVDGALFYHPDLSELAVTEAKIEEDAQSIDRFILSAPFTHPYITKIHPLASTIICKKGDQIVFEGRVLDDGTDFYNTHTWICESALAFLKDSLQPPYHYQGPLRGLLELFLSSHNSAVEEKKQFVLGTVTVSDTNDYVAYENGDYSVTLDAIKEKLLDTHGGYLKVSYTADGKKQLDYLADFTAASLQTVEYGKNLLDVKINRDHTKRVSMLIPLGAKSTETDSEGNETERRVDITSVNGGLNYVEDADTTAEIGKIWTTEIWDDVTLPENLLRKAQARLPELKDGITSMELSIVDESDTGSTLSEMHAGEYIRCLSKPHGIDGRYLCLARTRDYLHPASNTITIGARNITLSKAATEQSKNLEALSVDIEGKTEEINSAVSKADTALAEATQAKDAASSLEVNVQQFYSEITKTAEQINSAVREEYVSKSDLETLRQDFSSSITQTSTELRLDFHAKTDEIRGNVIANQQLLEEYIRFRGALIELGKIGNAFTAELSNEQLAFKENGQVIAYISNQSLVITNAEIRYRLSLGTEGRGWFDFIPRPTGNLSVVWRASSN
>NZ_LT632322|348035:424895|414174_414621_+|WP_071705085.1|DBSCAN-SWA
MRSKVFNTPFENMLRILLLADTINKPMNVDRFVALDFICIFGEKCRVLDKNLHGDNEFGFSEFATKRERIAEAVKIAVKNDFLTVKATDAGFTYGMNNRGKAIVSGVQSPYAHSYIVGAKIVNSRFARYTDDEILQYISDLSSEAEEG
>NZ_LT632322|348035:424895|389687_391289_-|WP_071706055.1|terminase|DBSCAN-SWA
MRKLKDYQPTRFMAEGSHYDKQKADYAVAFIECLKHTKGTWAGKPFQLIDWQERIIRDLFGIVKENGYRQFNTAYIEIPKKMGKSELAAAVALLLCCGDGEQRAEVYGCAADRQQATIVFDVAADMVRMSPALKKRVKILGSQKRIIFHPTNSFYQVLSAEAYSKHGFNIHGVVFDELHTQPNRKLFDVMTKGSGDARMQPLYFLITTAGTDTNSICYETHQKAKDILEGRKVDQTFYPVIYGADKNDDWTDPEVWKKANPSLGITVGMDKVKAACESARQNPAEENSFRQLRLNQWVKQAVRWMPMEVWDKCAFPVDPDKLEGRVCYGGLDLSSTTDVTAFVLVFPPEDPEGKYDILPFFWVPEDTLELRVMRDHVPYDVWEKQGFLNTTEGNVIHYGFIESFIEELGEKYNIREIAFDRWGAVQMVQNFEGMGFTVVPFGQGFKDMSPPTKELMKLALEERLAHAGHPVLRWMMDNIYIRRDPAGNIKADKAKSSEKIDGAIATIMALDRAIRCGNDTSESVYDSRGLLVF
>NZ_LT632322|348035:424895|412203_412707_-|WP_071705084.1|DBSCAN-SWA
MQNNDNLSKKIYDKNTHIWFEVSDKQYRDYDRWRTALRKRRQYHGECSCPRPKFWLCDGNCPYCEFRIVKTVSLDMPLPDGEGTLSDYVSDHTPTPEEIITDYDLLDHLFVRLHEIDSEADRIIEIWMDHPDGISDRKVAKLLGRKQRTFADEMKKFRDEFKAERNK
>NZ_LT632322|348035:424895|410458_411595_-|WP_071705082.1|DBSCAN-SWA
MPNKHALLSASSAYRWMACPPSAKLASSYKDESSTYAAVGTDAHSLCEYKLKTALGRKADDPTEDLTYFNEEMDASSDAYAGYALEQLEAAKKGTADPVVLIEQQVDFSRWVPQGFGTADCVIVADKVLTVIDFKYGQGVLVEAENNPQMMCYALGALSMMDALYDIEKVIMTIFQPRRDNISSFRLSVKTLYDWAEKELKPKAHLAFEGKGDYAAGDWCRFCKAKVDCRARAEANLALAKFDFEMPPTLSDADIEAILPMLDDLTSWAADLKDYALSRALSGKVWHGFKLVEGRSNRRYLNEEAVAQTVIDAGFDPYEKKLLGIIAMQKLLSKKRFEELLGSLIEKPQGKPSLVPESDKRPAMQTANQDFKEENDND
>NZ_LT632322|348035:424895|406641_407334_-|WP_071705078.1|DBSCAN-SWA
MKELIPKDKYGVFADNHDTARVDSRAVAQFFGKRHDHVIRDIEKLILPKSGEIYPSSGMSLEFAQLNFGEISYVDDRHRRQKAYALTRDGFTMLAMGYTGKKAMKFKELYIRRFNEMESFIKTLVSARQEFPLLTENIRLLHDNPKPYHYSNECDMLNRIVLGMTARQFREAHGLEKGTSIRPYLEKEQIDLLETLQKVDIGLLLSVPDYQQRKQYLEWYAMKQQMKEVR
>NZ_LT632322|348035:424895|372679_374251_-|WP_083428144.1|DBSCAN-SWA
MKALKKVTRIDGVATQRKQQKQMRIAVYCRVSTESDAQLESLEAQRKHYASYICTRDGWTLHDIYYERGVSAAKSKARPELRRMLRDCRLGKIDLVLTKSISRFSRNTADCLRMVRKLLELKIPVYFEKENINTSEMESELFLSILSSMAQDESASQSANVRWSIEQRFQSGTFIITCPPFGYRNDDGVMAIVENQAVIVREIFQLALAGYGGYSIARILNDQNIPSAHGGLWSSGSILAILKNEKYTGDCLFQKTYTDDAFKRHKNNGEKNAYLVRDHHKAIIDRKTYDAVNELIELKRENKGIIQESPKYLNRTVLSGKVRCKACGSVMKRITRYTQSGSYKMYACSTHLHSKKNCPFKAVYEDGILCAFASMMNKLTFAREAILEPLLSEMQGQKPKTYVKELKVANEAIREDSDKLDVLTRLSASGYLDRPHFLKEKNKLVTRIEERKKEREQLKIQEAGKDDTVINLEALCHYVKGRKVSERFCEEEFKRFVDAVEVVSRTEVCFILKCGLRLPERLA
>NZ_LT632322|348035:424895|391404_391635_-|WP_071705062.1|DBSCAN-SWA
MTNKEHKAQIFQNTTKARQAKIEEQITKLAFEMMPSLEGRSDLEEHGNDAEDFLETSIWSLKDALMAAYRLGQQNA
>NZ_LT632322|348035:424895|417728_418574_-|WP_071705090.1|DBSCAN-SWA
MKHNLLSVKNISFSYNHFDLKEISFEMNAGEIIGFIGQNGAGKTTTLKCITGQLSTNKGSISLLDYDINLDPVHFKSNIAYVSEDTSIYDMLSLKQFVNIFKYFYKSWDQNMYEKLMHRFLITDHNKKIAQLSKGMKMKFYISFALAHHAKLLILDEPTSGLDPFIRTEFLELLKEKKEEGVSTILSTHITEDILKISDRIIFISNGKLKFDLPAQGIEHSCFLVEEQALSTLNLDNYVTLLSKGAELVIWCKSLDSSNLIRYSDHFKPLSFENMLSMLNN
>NZ_LT632322|348035:424895|398693_399080_+|WP_071705072.1|DBSCAN-SWA
MRKKKILKIILIISISILLLPILYIAAFSIYMRIPQTYVLKPASPYTGAQLVTKTTHSFRGNHSKIYIRYPNSTKLIDTEESFGVDEARPGLTRDDAPYTLTWINEHEAKIEYIYAGPDVIYEVTIQY
>NZ_LT632322|348035:424895|419988_420936_+|WP_071705093.1|DBSCAN-SWA
MSKKHSRNWMITSILLLCLCTLTACMHQQPAEEEINESFYKMSRTSSQLYETKEIGLKSMGIQRASGLLYFKDHIYLSDSSQSEIKVFNQQWNLVESIHSKKIASPSLLAAYGDRLAILDKATSQIVLFDIPSKKEQSVIILPSIDSDSNYADMEMSKNDLLITYHTPAFEDANVLRIDLSTRKNKKIQEKFNGFVGTTNGKFYLVNSLVAFQESDREGFRSGKNSLWTLEDSKPKAIGNLIEGSAPGDFLWNGEILFQYTSGWSSIDRYDKSFNYMDSIAVFDQSDIQSLLKGNEQQMYLLMPNEQKLFEVHKK
>NZ_LT632322|348035:424895|411584_411923_-|WP_071705083.1|DBSCAN-SWA
MGQVKRAAAIVEELRACSEKLNDLANELNELFFGSTDERGNAPAPQPTPKPEPEKPALKLEDVRKVLAQKARAGLTDEVRALIQKYGAERLSDVEPIHYAALLADAEVLHAE
>NZ_LT632322|348035:424895|354102_355368_+|WP_071705036.1|DBSCAN-SWA
MDEQERLEQTEEWNEDARKAQSPHYEEAATRRIVREEIARNYRPKGSAARAVALVLCGALLGAGGGAALVASGNIPLPQQQEQAASATTNGNINISLKEGQTTVENAIAAKTIPSIVGITTIAKSVSNNPFLYGTPQYSESVGSGVIVSADGYILTNAHVVNGGNAKTVRVRLSNGEEAEAKVLWADPTLDLAVIKVEKKNLPAITFGDASKVQVGDKAVAIGNPLGLDLQSTLTSGYISGLNRSITLQDGNIMDGLIQTDAAINGGNSGGALLNAKGELIGINTAKPASADGIGFAIPVSTVKPIVDKIVADGTYTPLYMGINGANTKLVAASGVEGLPTDSGVVVRDVVAGSPAATMGIEPYDIIVAINNEPVESMNTLKTLLLKYKKGDTVDVTYYHGRDKKTGKMTFTDFSPEAIQR
>NZ_LT632322|348035:424895|407653_409642_-|WP_071705079.1|DBSCAN-SWA
MKTLSIDIETYSSVNLAKAGLYKYAESPDFEILLFGYSADGAPVEVIDLASGEEIPSEVLSALTDDTVTKWAFNAAFERVCLSRYLAGLGISLDPFLDRHPLSRECARFLNPASWRCSMIWSATMGLPLSLEGVGAVLGLKEQKMKEGKDLIRYFCTPSRPSKTSQDYLRHLSSDAPEKWTIFKEYNRRDVEVELAIKERLRNFPPLAFLWEEYAIDQEINDRGVKIDWKLVEAAIRMDEESRTELLTEMKKLTELENPNSVAQMKDWLAENGMPTESLGKKQVAALIKTAPPKLQKALLLRSQLAKSSVRKYQAMQSSACADGRVRGMFQFYGANRTGRWAGRLVQMQNLPQNHLPDLSEARALVKSTDYGVVSMIYGNVPDTLSQLVRTAFIPKAGCKFIVSDFSAIEARVIAWYAHESWREVVFARNGDIYCASASQMFHVHVEKHGINGHLRQKGKIAELALGYGGSVGALKAMGALETGLSEEELKPLVTTWRESNPNIVQFWWDVDQAVMDAVQHRSVRKTHGLTFACKKGMLFITLPSGRNLSYVKPRIGMNDFGSPCVTYEGITSGKKWDRISSYGPKFVENIVQATARDILAFSMQTLRCCRIVMHIHDELVIEADPAMSLEAVAKQMSRTPPWAKGLVLNADGYECEFYQKD
>NZ_LT632322|348035:424895|359641_360526_+|WP_071705038.1|DBSCAN-SWA
MKTIAQWAALLPQQEGYLALSYVLDTTPGALRAKSGESLDTAVTERYQEIVRRRLAGEPLQYAIGEWEFYGHLFQVDARALIPRPETERLVEMALQEDLAGKLVADIGTGTGAIALSIALEAHPKPRKLYATDCSADALVLAKENAARLLSSRGGIHAQPASAQPVPNDASASSQNMIEWVLGDGPSALPEAVDVLVSNPPYIDPQEKESLQDELQYEPASALFAGEPGKGGLALYQEWIPLLPARLQSHGVVLMEIGDRQGEAVSSLFRQAGFSAVTVHPDYTGRDRIVRATR
>NZ_LT632322|348035:424895|380998_383851_-|WP_071705053.1|tail|DBSCAN-SWA
MADRIKGITVEIGGDTTGLSKALSGVNKEIRNTQSQLKDVNRLLKLDPANTILLAQKQKLLKDAVGETKDKLEQLKSVQEQMDAGLKNGTLTQQQYDAWQREIIATEQELEKFEEQVKSSDSAVSATLKETGSKLQDVGGKISGVGESLTKGVTAPIAAIGAASLAAFSEVDEGLDIVTQKTGASGQALEEMQSIVKSLATEIPTDFATAGAAVGEVNTRFGLTGQALSELSGKFIKFAQLNNTDVSTSVDNVSSVLNAFGQSTDDAGSLLDALNATGQSTGISMDQLARGLSSNAAQFKEMGLSAEEAAGFMGMVEMSGLDTSAAMMGLKTAMKSAAADGKSLDEALQGFSDTMNSNQSETEKLQAAYDLFGTRAGAAIYNAVQTGKLNLEDLSGMLGDFSGSVENTFSETLDPIDQFQMTMNSLKETGADIGNSLAAVLAPVLERISEGLKRFSEVWQSIPAPAQQTLVTIALIAAALGPLLIVIGKVVSAVGTIMTNMPAIAGAITKVKTVMSSLNATLLANPITLIVAGIGTLVAAFLHLWNTSESFRTSILSTWNQIKEAFSAFESGIIERLNALGLNFTSFGQLISAIWNGFTQLLAPVFQGAFQAIAAILQGALHVLTGIFDIFTGLFTGNWSTVWNGIKEVFSGVWTAISGIFSSVWATIQGVANTALGWFGATWESVWNGIKSFFEGIWNGIAGFFSSIWNAITGTVSGALSSISGTVSSVFNGIKSTASGIWNGIKSTITGVINGIKSGISTVFNGIKSTVTSVFNGIKSTATSVWNGIKTAITSPIEAAKNTIKGIVDSIKGFFSGLHISLPKIKLPHFSISGGFSIIPPRVPHLSISWYKEGGIMTNPTLFGMNGSSLMAGGEAGPEAILPLEGFYKELRSILTSQLNTEGMEKYLAVIAANSSKGIYLEDGTLIGKLLPVIDQKLGQEQKWNARLSL
>NZ_LT632322|348035:424895|348035_349751_+|WP_071705031.1|tRNA|DBSCAN-SWA
MRMKRFYMPTLREVPGDAEVPSHQLLLRAGMIRKAASGIYTYLPLGYRVVRKIEEVVREEMDRAGAQEIRVSNLQPKEIWEASGRWDTFGPEMFKLTDRHEKEFALGPTAEEYFTDLVKEELRSYKQLPLNLYQIGWKYRDEKRPRFGINRSCEFLMKDAYTFDIDQEGLEAAYQVMWDAYVRVFDRLGINYRVVQGDSGAMGGHVSHEFTALSEIGEGVIVYAEGGYAATDEKASMQKPTYPAEEPLPVETLDTPNAHTIEELEDFLHIPAHKMIKAICLRISGEPVFVFMPAERELNMSKLIAYLHTPEHEIEMLDDETIERVTGAPAGFTGPVGLPDTVRTIFDAAVTTRENLVCGANKADTHLKNVNFGRDFDGEIAEDLWMVAEGDLDPIHGNPLQFARGIEVGNIFQLGTKYSEALGATVLDENGVARPLVMGSYGIGVTRVVSAIIEQNHDEKGMIWPLIAAPYHVMITVMKTNDETQMQLADALYERLEKEGVEVLLDDRDERPGVKFNDRDLIGIPLRITVGRNAAAGMVEYSTRREMTNEDVSVEEAVSRVAAAMETLREV
>NZ_LT632322|348035:424895|420995_421988_+|WP_071705094.1|DBSCAN-SWA
MLEVLSLSVVFYFALMFVCKLVDTHGDIAYYRSRTNVGEVVYQLEKAPEAKISDVDFTLYQKADQYVTVHSKTYKAQVIGIDQNFSSFYHDHLFQNIVKKKALSHSDAILSQSVAREMSAKEGDTLTLNHQVLKIIGITDDPWWKGKVAVSFSILSASELAQPKSLYLTIRRENVELVENQLSVLDQTDLAQSLQNEINSLRAFQRFLLSFSAVFFLIAGCNLMLILRTRFRRERGLHQILYLCGETRGTYYLASMIDGLTMCISSDFIALLIYLLMRPFVPSFFYFALTPTIYGLEMLMVAMISIIITLIFSHEQAVYIRMNERKTHAV
>NZ_LT632322|348035:424895|361684_364063_+|WP_071705040.1|DBSCAN-SWA
MDKEQFLKQWNESTKRLFCKTIETATSFEKYAALSQTIMDHITDAWMETREKTKTMRNEYYFSAEFLVGRALGNNLLNLGILDEVKAVLKDIGIDFEQLEDEEDDAALGNGGLGRLAACFIDSAASEGYPVQGYGVRYSQGIFEQKFIDGFQREEGDDWTKKGDFWSQRREEEAKLVRFRDETVLAVPYDMPIIGYKNGIVNTLRLWQAEPLESGFDFDRFNNFQYDDALRELNRAEDITRVLYPNDMQRAGKVLRFKQQYFFTSASIQDLLTRYKENFPEDTNFRSFSALHSIQLNDTHPVIAIPELMRLLIDEEELSWDDAYDVATHTFAFTNHTVLQEALEKWSLDIVDEVCPRCLELIKEINQKMISVFRQQGMPEEQINTYRIIHDNVVEMAYLAVWCAVAVNGVAKIHTQILQTETFKQWVAVMPEKFSNKTNGVTPRRWLQYANPELSAFITKKLGSDAWHHDLTLLKGLERYADDPETLTELNAIKAIKKNQLVDYIERTEGITLDPDSIFDIQIKRLHEYKRQLLNILHILHLYNMLKKNPGLDMVPRTFIFGAKAAPGYFRAKAIIKFINEVARMVNADPDTRKKLRVVFVQNYRVSSAEKLFPAADISEQISTAGKEASGTGNMKFMLNATPTLGTYDGANIEIIADAGEENNFRFGATVEELEGIASSYNPLEYYHTKPEIKEVVDYLLDQRLSDHGTYMFLDVYNSLVAPQHGERGDEHYLLYDFESYAEAQKRVDTAYRDRLGWAKKCLMNLANCGEFSSDRTVREYVRDIWKVDTIQ
>NZ_LT632322|348035:424895|376441_378643_-|WP_071705051.1|tail|DBSCAN-SWA
MASSGSFSGSIHGGHYVLRVDWKQTKDITNNHSTITATMVLVNDWTLYISGRTNNTCTIDGQSQAFSSPAVDTTGSHTLGSVTKTVNHNSDGSKTLNISAVFHIEATISGTYYSTITANASITLDSIPRASSVSASSISMGTATTIKISRAVSSFTHTLAYRFGSVSSAIAIKTTGTSLSWTPPLSLASQIPNSTSGTCTITCYTYNGGTYIGSKATTITLYVPSTIKPTIGSLTASHIDGTVPSTWGVYVQYKSKATLAISGATGSYGSTIRSYSITGGGFSGSSSSLTTGFLNDYGTTTFTAKVTDSRGRTSDAKTVSISVLPYYSPRFLSAQSERADSTGTPKGDGTYVRALLEFYFASVGGKNTITTSVSYKKESDATWTDAATTFTSNTPFTFGSGSISPENTYEVKYTLTDAFTSISITDSISTAAVVMDFKNGGNGLAIGKVSEIEKCFEVAPDWSVKVYGLLLPAYIASLSGGLPFGVCNDAADVVEKTGECPDFQTLNTGAVVLMKFMHNNTATFPRINVNGTGLKYIVNVGRTAVGTNYWRPEQTVILIYDGIFWVALTTPLADTSYFGITKLSTSTSSTSTSTAATSSAVKAAYDRNSWPSISLTSPLAVSSGGTGASYASAARSNLGITATSLYSGAITTGSTTFSKSYNFFVIIGQPSTASSRCALVVPSAQLTTTATNYQIADESNYYAFKLYYSGTTVTLAYYDRSSNGQIIRVFGVN
>NZ_LT632322|348035:424895|355740_357900_+|WP_071706049.1|DBSCAN-SWA
MATTTKQPHPAQHTAENPALPEALAPLFTPWKIGTVEIKNRIVLTSMGGTNLLGWMEKNHFDETGAHFIRTIAENNVGLVLPGCQPVYNPMFGQWLYKNKRMYDDLAKWLPAFHQTGAKLFVQLTAGFGRSFTISPMMETLYTNPVLRFLSKPVMNLDKITASASEAPNRWSDKVPSRAMTVAEIQQMVEAFGKSAKLLKDAGVDGVEVHAVHEGYLLDQFTLKYVNHRTDAYGGSRENRYRFPVDIVREIKRVCGENFPVSLRYSVESKTKGFRQGALPGEEYTEVGRDMEESRWAARYLQDAGYDMLNCDNGTYDAWYWCHPPIYMPENCNLDEVKEIKKAVTIPVVPAGRMDPYVGAKEVAAGTIDGVGFARAFLADPEWVTKILEGRSEEIRPCICCHNACFNMSKWKGTPNMQELQDSLHLARCAVNAETMQWDKHYIKKTDAPKTVHIIGGGVGGMEAARVLKLRGHNPVIYEQTDRLGGVVIPGAAESYKKPMRDLLAWYRQEMERLDIPVHMNQSIAPDHDFGTDPVIVATGGKPISLSRVPGFDRTIEATDFLRALEGRREEEGVAVKKGVGRRVAVIGGSLTGCEIAYELALQGKEPFILEMKEDLIATEGVCLANSSYLREWFALHKVPVYLESTLVEVKEDAVTYKDASGALHEVPCDSVISAVGYRPDPLLDKAHTGAQTYFIGDCAGIGNIKTAVWQAYETAMKI
>NZ_LT632322|348035:424895|366656_367571_-|WP_071705043.1|DBSCAN-SWA
MKQKRLLLALALSGAVLTACSSNPGFELVDAPRQESSGVEETKEVTELMEQEFAIVTEVDDTVKPGEYRIVQPGERGQSNITYEVSMSGGKEVSRKALSETVVKKPVEAIVKIAPTAKHGEIGAREIIGYSNPTSPHFVKPTTIGATMTDNSLVLRILADGKVEKDNFMVAQSSEKPRTEPSTTEKSRVPDIRIVPAPSRGGKTHTPTPTPPPAKPKPPVIPVLPNASSAPASSEQSSSSSSSQEQSSQQSSSSSSAQTSSDTQAPSSSQSQSKPESSKSSTTEAPPNPNPSGENTSPEEKPAP
>NZ_LT632322|348035:424895|399112_401524_-|WP_071705073.1|DBSCAN-SWA
MDVMVQKTQEWLNKTYGSDSRFKKLKITGHTGWATINALTRALQIELGIQNTADNFGPSSRQLFSKRYPNGVKQQASNDKAESNVYAIIQGSLWCKGYRAEYGDITKHFYDGTAQGIRQLKDDMGIGGDSTVTLQLMDVLLSMKQFVLLASYGGRNDIRQIQQQINRKYETYTGIIPCDGIYGREMNTALIQILQSLEGYSPEDATGYFGNGTKSNLCKITSSNASSYGNWVWLAKVALNCLGYNCRMNNVWDESLNSSLQTFRADYALPKGSSIDVNAWMSLLTSKGNPDRAAKACDTRFEITESLLKKLKGDGYQIVGRYLTGGSFKEIREGELDRITKGGMKYFPIFQDNGREISNFTYAKGKIDGATASKAALAKGVPSTVIYFAVDMDAYDYQIDSNILPYFKGVNETISMEYSVGIYASRNICTRICDTGYAISSFVADMSTGYSGNLGFPIPKNWNYDQFYEISGYSGSWDLDKVAYSGKIPACATVNQANGNYFPYSLPTTFSNTELTAKTKISTVFPLIKELENAYKDYLKNGYDPLLKMPIYSPAVGALQYLAKSYFLDDALKGIGFSIVSSTTYDVVFDVYVKKNYPALANNLAHYISGDKNSLWDGERGVIDLPHLAITTLSYYNFTLNPGSWNGWAGDLVSAYGLVRDYYKNNPGDNLQQIARAYVGGEFPKKDLPHAPNAKENPCNYTDLCSDGYAIVLSQNLKESDGNLGASFEKIFTTDRGTQFMGLLTDIDATKDVMDIKDKVKDVVKDALADLLSRLENDNSDSPQEVKDACILSFAKWLYLNLG
>NZ_LT632322|348035:424895|417104_417719_-|WP_071705089.1|DBSCAN-SWA
MINYVRKDLSTTKWYHFIALVVSMSATGLLCLDRGNYSFMGLYICLATCFTYIIGQSCFFDEKGESKNWIKTLPHYAGQIVDSKFVLSLFTIAEGSCLYLISNLLIATITPYRVSFSSEIFILMGSFQLAYIALFLYLFYRYSYSIARSSMLLMLVALLLTKMIGSGKYLHIPDIPFESLPYITLIAGVVVFILSWLNCRKRIK
>NZ_LT632322|348035:424895|403581_403863_-|WP_071706056.1|DBSCAN-SWA
MLEKELEQKLVKAIKAKGGLCLKLTSPSMSGLPDRLCLLPDGKIGFVELKAPGKKPRPLQLKRHEQLRHLGFLVFVLDEETKIGGVIDAIQST
>NZ_LT632322|348035:424895|392239_392428_-|WP_071705064.1|DBSCAN-SWA
MDGKIKEQILTIRDSGLTNMFDATAFQRLAFERGYYELVLFIEEHPKAYAHFILTGEENIEK
>NZ_LT632322|348035:424895|413225_414185_+|WP_071706057.1|DBSCAN-SWA
MDPTRRGGDFVIALVGEVLRDPMTEEEQQMDLQHEFNPLANRISINMLDQIFEGKKFISKARACLICSRYDGQEFADVIDNLYDANKEHLQTFLDNRGISVAIEELGSAVQDVLHQIFHGLAKGYHDVDIELTIHDPKPSIKNLAGNRIYCEDGKLYIDGDVIELPIKLSDAQIYDFEAGYISALCDAYAEALSRDSVTVDDIPFLPQKYRHNFYDQRKAYLSAKSIQRSISEVYDDGENQFDILKEDAYGGIKITYYDDYDNGYRRLLEVLKKISDVQLAKSRLMMIRNLIGNLERLGIVHILVNDQTIKSWVDPYEE
>NZ_LT632322|348035:424895|392427_392658_-|WP_071705065.1|DBSCAN-SWA
MRRRRMRKELLEHLRLKYPVGSRVELLHMDDVQAPPQGTLGTVIGIDDMGSLLVRWENGSGLNVLFGVDEVRKVGR
>NZ_LT632322|348035:424895|380351_381002_-|WP_071706052.1|DBSCAN-SWA
MKPDVFFNDVSLFSMGWLRESVDFPVPLSQSESLVVPGRSAPLRFTQALGKVSFQPRSFTITLSMFGTRARFDALVSTTVNRFAGQLVKVVRTEDKSVYAIGTLEAESSYDPRTYKGVLVFSSKDADAYLYHVQETTKSLTGSGTLSLANDFMPVVPSITTTAETTLAWQAGADAFTKTLSAGTWTVPELELAPGDNTITVTGTGTITFTYLEGRL
>NZ_LT632322|348035:424895|370695_372291_-|WP_172619971.1|DBSCAN-SWA
MSITRSERLKMNKNITMIPARKKQGNTKTETPSPTLRVAAYCRVSTDSDEQATSYEAQVAHYTEYIQAQKGWELAGIFADDGISGTNTKKREEFNRMIDACEAGEIDIIITKSISRFARNTLDCLKYIRKLKEINIPVFFEKENINTMDAKGEVLITIMASLAQQESQSLSQNVKLGIQYRYQQGKVQVNAKWFLGYDKDADGHLVINSEQAKTVKRIYREYLEGLSMNKIAAGLEADGIRNGAGHTKWTPSNIRQILTNEKYIGDALLQKTYTVDFLTKKRVRNEGHMPQYYVENDHEAIIPKEIFLLAQDELVRRRNLSKRADGKRKAYSSNHCLSGLVICGECGEYYRRIHWNNRGCKSIVWRCMSRLTPGNNSCHARTVEEEFLKGIVLSAINRCIKDKGCFFAELEDRITHVIDHESSVDMKSIEQRLEDLQQMLMDRISNREPYEDVANEIDAVKEEKMQAELAQAKTDNQILRIQAMRDFLQAQTGILTTLDDALVRRMVDTITIHDKKIDVRFTSGVSVSIKQ
>NZ_LT632322|348035:424895|383913_384096_-|WP_071705054.1|DBSCAN-SWA
MRSEREMTTPLLMLRALEIGLSVRDLDLISIGLLLDMWTEKANDQVKYRRIATQEDFDRF
>NZ_LT632322|348035:424895|424334_424895_+|WP_071705097.1|transposase|DBSCAN-SWA
MNDFTTDAKMAQTNKISLTEIVHQHVEDAVNQLLENELTVFLDHEKWDIVAKNTDDCRNGYYECTINSEYGPLHLRVPRDLMGDFEPHTVRKRARSTDGLEQTIIQLYQKGITTREISEKWAPTYPQLKKVFERRDNLFSFLAFLESVRRSLYTNNLAESLNKGLKRMIKVKEQFPTEDTLERGVC
>NZ_LT632322|348035:424895|397347_397923_-|WP_071705070.1|terminase|DBSCAN-SWA
MAKDGTNRGGRRIKAGSKPDPLIDKIAAGKSAKILNPELPDVTLLVGADIGEGAELEGMDMPEPGEYLSAKQKDGQPFYADDLYRETWQWLKDRGCEHLVSPRLLEAYAQNFARYIQCENAISHFGLLGKHPTTGGVVTSPFVTMSQSFQKQANLLWYEIFDIVKQNSTVSYEGQTPADDMMERLLRSKKG
>NZ_LT632322|348035:424895|386073_386352_-|WP_172619972.1|head,tail|DBSCAN-SWA
MDIISLAEAKNYLRVDFSDDDVLIADLLQNATSLVANVARLNLETELAGVKNAPVAILYTVAYLFEHREEADHHDLTLTLRSLLFGDRKAGF
>NZ_LT632322|348035:424895|374299_374494_-|WP_071705047.1|DBSCAN-SWA
MTNDINNKQPLPVQEDLMRDVYYRLAEAYVDELYAQGILAECEAQILHRQNRSVYRPFLYQLME
>NZ_LT632322|348035:424895|349888_350692_-|WP_071705032.1|DBSCAN-SWA
MKRRFFIVLLLLFLLCPSLSHADMGPKPYVSVHIAGSDTRYYATLLSSSAEYGPWRANAVWTTDAPDSIQQKFQQFSLPEDHYFLGYVAEAAPRDFCWSYYPPETFRILLYDEKADHFLMSAPLTRHALKNEYTVTIKEDRITDIHFHYDYLADVPKLLALIAGTILIELAVAYLMGIRETASLRYIALVNLGTQALLHLGLWFIGFRLGTTGIMPVMRPVLLLPLEALVLGIEALLYRRKLPKEQHPVRYAILANLVSYTVSLLIP
>NZ_LT632322|348035:424895|393363_394935_-|WP_071705067.1|DBSCAN-SWA
MPNLTLGSLFSGSGGFELAAKHVGITPIWASEIEPFAIRVTTKRLPEVQHFGNIEDLSGRTLPPVDIITFGSPCQDMSIAGKREGLSGSRSNLFYEAVRIIQEMREETHGNYPTYCVWENVPGVFSSGGREDFRIVLESLCRIKDKTISVPASSKWTNAGTIMGDGYSIAWRLLDAQYFGVPQRRKRIYLIADFAGQGAGKILFESDGLPGNSSKGIGARQSTAGRSERSAGDASTLCLMDQGGSRMDVIKNRTNTLRAKANHPPLVFENHPQDARVTGPLEKAPATTARYGTGGGNTPLIAEPKTLKIRSGKEGGGKGALVQDNLSATISTHNDQTLFEPVAYGFNAVHKESGAGRFGYKTDLSKTLDTSGISPTCNQGGIAVVFSTSKTSYHTDALQDQANTLVASDYKDPPIINANSGPQYMVRRLTPTECARLMGFPDPWCQDLSEPNPSEDDLVFWREVFLEWQSTQGKTPKPKTDKQLQKWLADPYSDSAEYKLWGNGIALPCAEYVLRAIAENQKK
>NZ_LT632322|348035:424895|353417_353957_+|WP_071705035.1|DBSCAN-SWA
MQRTTKQPRRRWMQIAASIPNREKEEERRQDLERFHAKVGDEKEWIVMRLDDVDALIEQLTRETETIRESLDRPHHERVSSLAPLTEAGKQHLSRKRLLRSSAELDVLLLEVHRHPVFRDIVADMQNLTVPETTLPVENESSVVASRKMLSIRDQLSDLLDNLYRLRRRLRRELLRLAR
>NZ_LT632322|348035:424895|376035_376431_-|WP_071705050.1|DBSCAN-SWA
MQILTDEQGFITSFALDGMLVGGAECAEPEDIEDFALHYQCYRIRDGDLVLDKKRLVAKSKNAAKDAIRERRCKECFPVINRGTPWYDRLTEQQKKELNAWYLAWLDATETGAIPEMPEWLSTYYVLGGTR
>NZ_LT632322|348035:424895|387641_388415_-|WP_083428145.1|protease|DBSCAN-SWA
MLEPLPTLKHQERRNKTVKKKFWNWKVNHSKDGAEERILELYGTIAEESWFDDDITPVMFKKELFNGDGPITIWINSPGGDCIAASQIYGMLMDYPGEVTVKIDGLAASAASVIVMAGTRVLMVPTALMMIHNPATAAFGDHGEMERAIDMLEEVKESIINAYEIRTSLPRKQLARMMEDETWMNAKKAIDLGFADALLTDSKREVPADLESYSFAASAVDRALVAKMKEKLKPQEMELPVGRSVDDLKASLYKKLL
>NZ_LT632322|348035:424895|375619_376039_-|WP_071705049.1|holin|DBSCAN-SWA
MKEFWNSIQLIFTGIGGWLGFYLGGFDGLLYALIAFVITDYITGIMCAVADKKLSSAVGFKGIARKVLIFLLVGIGHMIDAQVIGTGSVLRTAVIFFYLSNEGLSLVENATHLGLPVPKKLKVVLAQLHERAEKEETHE
>NZ_LT632322|348035:424895|416452_416665_+|WP_071705087.1|DBSCAN-SWA
MKLSYKKLWVMLVERDMKKTEFAKKAKISSASLAKLGKGANITTNVLVSICETLKCDIGDICEIVPDDVV
>NZ_LT632322|348035:424895|364169_365036_+|WP_071705041.1|DBSCAN-SWA
MLVSAKEMLIKAAKEHYAVAQININNLEWTKAVLETAEELKSPVILGVSEGAGKYMGGHTTVAAMVRAMDEALGITVPVALHLDHGTYEGAKKCIEAGYTSVMFDGSHFPLEENLEKTTEIVRLAHEHGISVEAEVGTIGGEEDGVVGMGEIADPAECKRLADLGIDFLAAGIGNIHGVYPANWKGLDFDALQHIKEATGDMPLVLHGGTGIPKDMILKAISLGVAKINVNTECQLSFAKATREYIEAGKDQQGKGFDPRKLLAPGTAAIKETVKEKLEMFGSVGKAE
>NZ_LT632322|348035:424895|386428_387622_-|WP_071705060.1|capsid|DBSCAN-SWA
MNITEMRTKRAKLWNTMEGFLETHRNSMGYLSAEDNETYNKMEADLDAMTNEVKRMERRDAIEAELSRPVDQPLTQKPERAMTMKSEKAGRASDAYHEDFDRHLRGKQLLHNVLSEGVDADGGYLVPEEFEREIVMQLEEENVVRSLAKVITTQHERKIPIANTHSQAQWTAENAAYTESNPTFAQKQIDAFKLTDLCRVSVELLQDSAFDIEDYLMKEFARAFGVAEEEAFCVGTGTTQPTGIFTAQGGTVGVTAASSTAITADELISLVYALKSPYRRNAKFLMNDATISAIRKLKDQNGAYLWQPSLQAGQPDRLLGYELYTSPYAPVVAAGALTVAFGDFKNYWIGDRAGRTVQRLNELYATNGQIGYVATERVDGKVILPEGIQLLQMKAGA
>NZ_LT632322|348035:424895|360587_361673_+|WP_071705039.1|DBSCAN-SWA
MFESLEHIQSQLHEMEQQLADPALLADMNAWRKVNRAYVERKPIAKAYQEYKKAIDTAEEDREMLKEVQDADMEAMLKADLAEQEDIAQKKEEELKLLLVPKDPNDYKNVIVEIRAGAGGDEAGLFAGDLYRMYHMYAEKEGYTTEELDRTEQGIGGIKEATFMVKGEGAYSKLKYESGVHRVQRVPETESSGRIHTSTATVAVLPEAEDVDVELNLNDVRVDVYRSSGHGGQCVNTTDSAVRVTHIPTGIVVAIQDEKSQLKNKEKALHLLKTKLYDLELEKQNQEIASARHSQVGSGDRSERIRTYNFPQGRITDHRINRTIYQIHEFLDGDIGEMIEALQTEDQMKKLALVTDDSEQA
>NZ_LT632322|348035:424895|414623_416456_+|WP_071705086.1|DBSCAN-SWA
MQTFMIKRLRVSGCGKIDGIVEFTDGLNLIQGRSNTGKTWILRCINYLFGNDKRPYTPATGYTDIEGIFLTERFGEITLTRKLDENTVTVTSNNKEVENGEYATSYQQSSLQYLNDLWLRILGLDETIKVPKNACYGRERMSWRNVAGVFYVDEDEISSSSSIVIKGNSYEDTPLLASLLFLLTGDYKKGVAEILNAKQATARTQGILEYIEERTNALKQQRVSYIMQLEKLADHDIEYEIQSLSDNIQEVQQEIHELVEENKAIAQQLSGYEQRDANCSVLLGRYESLISQYKADLQRLDFISKGEKAVQELPSNDVCPFCGGEVHPEENVNFMEAINAEIKRIASELTVIAATVKSVEEEQAGIRANIVEFETRRSDLTSALVKKNNTVQNYKVSLQRYRDYTTLQNGIDFVNGQLEELGKKRIDELKPKKNLPQYHPKKEFEEEVGTNFTNLLNKILKECHYRLFGYTSWDFKHFDIHVDGEPKSDDQGQGFRSFLNSVVAIMLYEYFNKDDVYIRPGFLMIDTPLLGLDEDNEGLDKETIRSGLYEYFLNHQGEGQMIVVDNLNAVPNIDFEAYGINVVTYHKNERDGHIYGFMPSWRKDIPKESR
>NZ_LT632322|348035:424895|403991_406244_-|WP_071705076.1|DBSCAN-SWA
MKFTLFTADVTGAPTNCTYLHSAIITDEESLKAAASHDYVCASYKGNYRSNGNFLSSDCLAVDCDNDHSENPDDWISPADVAVAFDGVSFAVHFSRHHLKPKAGKAVRPKFHVFFPMEPVTKAADYTALKKQVCAIFPYFDTGALDAARFFFGTKDPQVEIHDGSRLITDFLNETDFDEGMAQSGTISEGSRNATLSRFAGRVLKRYGITDRAKGIYLEEAAKCDPPLEDSELRTIWHSACRFAKKVQSAEGYLSPEAYAKKNESLMPPDYSDIGQAKALVKQYGDELKFTPATDFLRYDGTSWIESKQRAISAMEEFLDLQLEDAKDRLAAARKALVDGGVKEADVTAGGKTLEKQIGEDTLKAYLAFLSASTYYAFVMKRRDMKYVTSALQAAKPMLEVNFESLDQDPFVLNCPDGTYDLAKGADGKREHNPADLLTKVTAVSPGEEGKELWLNSLHRTFQGDQELIDYVQKIAGLCTIGQVELEALIISYGEGSNGKSTFWNTIASVLSRYAGTISADTLTANVRRNVKPELAEVKGKRLLIAAELEEGMRLSTSIVKQLCSTDRIAAEKKYKDPASFIPSHTLVLYTNHLPKVGAMDTGIWRRLIVIPFTAKIEGKSDIKNYAKYLTDHAAPYVLTWMMEGAKKAIAEDFKFDMPACVREAINQYRESNDWLSHFLDTCCELDPAAQEASGILYEVYRDFCNRTGEFTRSNNEFVAALENRGFGRKRKKNGRFILGLKLLAEDFMD
>NZ_LT632322|348035:424895|423109_423790_+|WP_083428147.1|DBSCAN-SWA
MTPIIQLKDINKRVQDGTQSLQILKDCSITIQQGEMVAILGRSGAGKTTLLNLMAMLDNDYQGDYYFDQMNAHAKTDAERFSLRTKFIGYIFQDFQLIEEFTVLQNVEMPLGYQGVPRKVRIQRSLKAIEDVGLGRRGDSNVGTLSGGERQRVCIARALVHQPKIILADEPTGSLDPKTSEEVMTLLIDLNRAFNITEVIVTHDEVVANRCSRIYTLKNGGIHYER
>NZ_LT632322|348035:424895|358615_358819_+|WP_071705037.1|DBSCAN-SWA
MKQGIHPEYYENATVTCACGNTFTTGSTKKELRVDVCSACHPFYTGKQKTAERGGRVERFKKKYNID
>NZ_LT632322|348035:424895|409697_409880_-|WP_071705080.1|DBSCAN-SWA
MEYFQAILLVLSLFLFCLFGASLVIVEMQTYVYNREEERRKRRAEKREQEAHELRMKNLR

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071705031.1|348035_349751_+|tRNA	proline--tRNA ligase	A0A2K9L3R9	Tupanvirus	1.5e-06	25.7
WP_071705032.1|349888_350692_-	hypothetical protein	NA	NA	NA	NA
WP_097677427.1|350860_351541_-	YitT family protein	NA	NA	NA	NA
WP_147659358.1|352606_353005_-	hypothetical protein	NA	NA	NA	NA
WP_071705035.1|353417_353957_+	hypothetical protein	NA	NA	NA	NA
WP_071705036.1|354102_355368_+	trypsin-like peptidase domain-containing protein	A0A1B1IRH0	uncultured_Mediterranean_phage	1.4e-12	35.4
WP_071706049.1|355740_357900_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_071705037.1|358615_358819_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_071705038.1|359641_360526_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_071705039.1|360587_361673_+	peptide chain release factor 1	W8EDB3	Pseudomonas_phage	6.9e-05	43.8
WP_071705040.1|361684_364063_+	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-14	42.0
WP_071705041.1|364169_365036_+	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_157885047.1|366164_366329_+	hypothetical protein	NA	NA	NA	NA
WP_071705043.1|366656_367571_-	G5 domain-containing protein	NA	NA	NA	NA
WP_157885022.1|368977_370423_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	1.4e-37	27.5
WP_172619971.1|370695_372291_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.4e-147	53.6
WP_083428143.1|372253_372649_-	hypothetical protein	NA	NA	NA	NA
WP_083428144.1|372679_374251_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	9.4e-112	41.4
WP_071705047.1|374299_374494_-	hypothetical protein	NA	NA	NA	NA
WP_071705048.1|374688_375627_-	1,4-beta-N-acetylmuramidase	A0A2K5B2A3	Erysipelothrix_phage	2.5e-51	43.5
WP_071705049.1|375619_376039_-|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	5.3e-46	64.0
WP_071705050.1|376035_376431_-	hypothetical protein	NA	NA	NA	NA
WP_071705051.1|376441_378643_-|tail	tail fiber protein	A0A097PAT0	Streptococcus_pyogenes_phage	7.2e-33	33.5
WP_071705052.1|378657_380355_-|tail	phage tail protein	H7BV46	unidentified_phage	2.9e-50	34.2
WP_071706052.1|380351_381002_-	hypothetical protein	NA	NA	NA	NA
WP_071705053.1|380998_383851_-|tail	phage tail tape measure protein	Q6DMT2	Streptococcus_phage	2.6e-51	26.8
WP_071705054.1|383913_384096_-	hypothetical protein	NA	NA	NA	NA
WP_071705055.1|384092_384449_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	2.3e-10	36.0
WP_071705056.1|384445_385045_-|tail	phage tail protein	A0A0U4JWV5	Exiguobacterium_phage	1.9e-44	49.5
WP_071705057.1|385047_385368_-	hypothetical protein	Q6DMT6	Streptococcus_phage	1.8e-22	48.5
WP_071705058.1|385360_385744_-	HK97 gp10 family phage protein	A0A2H4JAN0	uncultured_Caudovirales_phage	2.4e-13	35.8
WP_071705059.1|385740_386073_-|head	phage head closure protein	NA	NA	NA	NA
WP_172619972.1|386073_386352_-|head,tail	phage head-tail connector protein	D0R0D7	Streptococcus_phage	2.8e-11	44.4
WP_071705060.1|386428_387622_-|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	1.9e-104	50.1
WP_083428145.1|387641_388415_-|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	3.4e-62	57.4
WP_071705061.1|388311_389622_-|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	7.7e-184	75.0
WP_071706055.1|389687_391289_-|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.3e-262	81.2
WP_071705062.1|391404_391635_-	hypothetical protein	NA	NA	NA	NA
WP_071705063.1|391794_392151_-	hypothetical protein	A0A2K5B283	Erysipelothrix_phage	3.0e-26	48.7
WP_071705064.1|392239_392428_-	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_071705065.1|392427_392658_-	DUF4314 domain-containing protein	A0A2K5B281	Erysipelothrix_phage	2.6e-18	61.2
WP_071705066.1|392635_393286_-	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	4.4e-39	39.0
WP_071705067.1|393363_394935_-	DNA cytosine methyltransferase	A0A1P8DJM9	Virus_Rctr41k	6.9e-38	26.3
WP_071705068.1|394927_396196_-	ParB N-terminal domain-containing protein	A0A1B0RXJ0	Streptococcus_phage	8.7e-92	42.1
WP_071705069.1|396192_397344_-	methionine adenosyltransferase	A0A2K5B278	Erysipelothrix_phage	6.9e-112	55.8
WP_071705070.1|397347_397923_-|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	8.9e-52	51.8
WP_071705071.1|398096_398480_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	9.5e-34	56.4
WP_071705072.1|398693_399080_+	hypothetical protein	NA	NA	NA	NA
WP_071705073.1|399112_401524_-	DUF1906 domain-containing protein	NA	NA	NA	NA
WP_071705074.1|401703_402168_-	hypothetical protein	NA	NA	NA	NA
WP_071705075.1|402236_403601_-	DEAD/DEAH box helicase	E4ZFK7	Streptococcus_phage	1.9e-145	57.8
WP_071706056.1|403581_403863_-	VRR-NUC domain-containing protein	A0A1B0RXC4	Streptococcus_phage	8.0e-22	55.9
WP_071705076.1|403991_406244_-	primase C-terminal domain-containing protein	E4ZFK6	Streptococcus_phage	5.0e-215	50.3
WP_071705077.1|406240_406642_-	DUF4406 domain-containing protein	A0A2K5B270	Erysipelothrix_phage	1.4e-27	45.9
WP_071705078.1|406641_407334_-	Rha family transcriptional regulator	A0A2K5B268	Erysipelothrix_phage	3.5e-87	71.7
WP_071705079.1|407653_409642_-	DNA polymerase	A0A2K5B2B0	Erysipelothrix_phage	7.7e-252	63.9
WP_071705080.1|409697_409880_-	hypothetical protein	NA	NA	NA	NA
WP_071705081.1|409893_410466_-	DUF2815 family protein	Q6DMW3	Streptococcus_phage	1.0e-79	78.2
WP_071705082.1|410458_411595_-	DUF2800 domain-containing protein	A0A1X9I6D8	Streptococcus_phage	1.4e-120	58.4
WP_071705083.1|411584_411923_-	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	3.9e-07	33.9
WP_071705084.1|412203_412707_-	bacterio-opsin activator	NA	NA	NA	NA
WP_071706057.1|413225_414185_+	hypothetical protein	NA	NA	NA	NA
WP_071705085.1|414174_414621_+	hypothetical protein	NA	NA	NA	NA
WP_071705086.1|414623_416456_+	hypothetical protein	NA	NA	NA	NA
WP_071705087.1|416452_416665_+	helix-turn-helix transcriptional regulator	A0A2K5B261	Erysipelothrix_phage	7.1e-15	63.2
WP_071705089.1|417104_417719_-	ABC-2 transporter permease	NA	NA	NA	NA
WP_071705090.1|417728_418574_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-20	34.6
WP_071705092.1|419620_419884_+	hypothetical protein	NA	NA	NA	NA
WP_071705093.1|419988_420936_+	hypothetical protein	NA	NA	NA	NA
WP_071705094.1|420995_421988_+	hypothetical protein	NA	NA	NA	NA
WP_071705095.1|421977_423102_+	ABC transporter permease	NA	NA	NA	NA
WP_083428147.1|423109_423790_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-27	37.0
WP_071705096.1|423779_424220_+	thioredoxin family protein	NA	NA	NA	NA
WP_071705097.1|424334_424895_+|transposase	transposase	A0A0N9STL0	Staphylococcus_phage	2.0e-08	32.6

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_LT632322|527613:539733|DBSCAN-SWA
TATGGAGCTATCTTCTTCCGACAAGGAAAGAATACAACATCAGTATGACGCATTGGCAAAGAAAACGTTGGTAGGCGAAGCGAAAAGCTACCGCCGCACCCTTGCGAAACGCGCAGCCCGCGAAGTAACTTTTTCGGATTTGAGCGAAAGCGAACTCGCGCAGCTTTTCACGACGGACGAATACGAAAGCGATTATTACCGTTTTCAAGTGTCCGGCTTTGATGTACTCGTCAAAAATGAACTGCTTGCCGAAGCCCTTAACGCTTTGCCCGAAAGGAAACGCGATATTGTTCTCTTGTCCTACTTCTTGGATATGAGCGACGCGGAAATTGGCGAACTGCTGAATGTTGTACGCACGACGGTTTTCCGGCACAGGAAATCCGCGCTTGCGAAGATCAAACAGTATTTGGAGGGAAAAGCAGATGATGAACACCGTTAGGAAATCTGAAAATCTGTTGCCGTTCCCTGTCATTTCCGCAGCGGCAAACGGCGACACAAACGCCATGTGCGCGATCTTGAAGCATTACGAGGGTTACATAGCGAAACTTTGTACCCGAACGCTGAAAGACGACGCGGGCAATACTTACTCCTATGTGGACGAAGAAATGCGTAACAGGCTGCAAGTGCGCCTTATTACCCGCACTCTTGCGTTTCATGTAGGCTAACTCTTTAAGCCCATGCGGGGAGCGTGTACCCCTTTCCACGCTTCCCGTTATGGGCTGTTTGTCGTTCCGTAAAAGCATATCGGAAACGGTATGCTTTTACAGGCTGACAAAGCCTTATTGTTCCTTGATAAAGAAAGCCCGCAAGATAACGGCGGCGCAGTATAACAGGCAAACGAATACATACCGCTTATATCGAGCCGAACAGCGGGTACGCCAGGACAGCTTTTCACACAGGGGAAGCCGAGCGAGAAATACCGCGCTGCAAAACAGGTTTAGCAGCTTGTGGGCGACGACATATAGGCGGGACGAAACGCCTTTATAGCCATAGTCCGAGCGTTAAGAGCGTCGCAGGCATTGGATAAAGCTGCCTTAAATGAGCAGGGGTGAAACTCCCGCGGTGCTGCCGCTGACAGCCGTTCGTTTCTGCCTTTCATTTTTAATCTTTTTGTTATCCCACGAAAGGGGGATTTTACATTATGGAACAAATGAAGCAAACAACAAAATCCCCGGTTGTGCGCGAATACAAAATCGGGGATATTACCTATATTGTCAAAGCCGTTGTTAAAGACGGTGTAAAAGAGGACGCCGCGACAAAGGTACGCCGCTTAATCCAAAATGACTTAAACCGGGGAAAAAGCCCGGTATAATGCCGAAAATGTAATCCTATTGCAGACGGACGACGGGTTTTGTGGTATAATATACATAACCTGTTTGTCCGGCTGTCGGAATAGGAGGTAACATGAAACAGTCGGATAAATTAACCGCATACTATGTTTGTGCGGTACATAAAACAGATACTTTGTACCTTGACAATCAAATGCAAAGACTTCTTTATCACGCAGCCCCCAACGGGTATGCAGCACTTACCGCAAAAGGCGGTGAGCGCAAATGACAAAGACATTTTCTTTTCAGCAGATTGCTGTTCCTAAAGTGTTAAGCGAAGAAGTCCGCGAAGCCATTTCAAATAATGTCTTGCAATTCTATGTGCGCGATCAGCAGCAGGAAGCGCAGGACGAGGGCATAACGGCTTTATATGAACGCCTTTCACAAGAGGACAAATTAGATGGCGAGAGCAACAGTATTGCCAATCAAAAGAAGATTTTGGAACGGTACTGCCGGGAGCATGGAATTACCGCTTATCGACATTATGACGAGGACGACGGGTATTCCGGTACAAACTTCAACCGTCCCGGATTTCAACGTATGCTTGCCGATATAAAAGCTGGAAAAATCAAGCGCGTTATCGTCAAAGATATGTCCCGTTTCGGGCGTGATTATCTGCAAGTCGGTTTCTACACCGATATGCTGTTCCCCGATTTTGGCGTGCATTTTATCGCGGTCAATGACGGAGTTGACAGTACGCGGGGCGAAAACGAGTTTACCGCAATCCGCAACGTGTTCAATGAAATGTATGCCCGCGACACTTCAAAGAAGATACGCGCTACTTGGCAATCAAAGGGAAAATCCGGCGAACACCTTACTACAATCCCGCCTTATGGCTATATGAAAGACCCCAACAACAAAAAGAAGTGGATTATTGACGAGGAAGCCGCAGCCGTTGTGCAGCAGATTTTCGCATTGTGCGTTTCCGGCATGGGACCGACACAAATTGCAAAATGGTTAGAGAAAAGCGAAATCCTCAATCCTACGTTCTATTGGTTGTCAAAGGGTATGAAAGTCGGCAACAAGCCGAAGCCGGGGGCAAACCCGTACAAGTGGACGAATGAAACGGTTTCCCGTATGCTTGAAAAGATAGAGTATTTAGGGCATACTGTAAACTTCAAAACCCGCAAGCAATCCTACAAGAGCAAAAAGAAGTTGTGGAACGACCCGTCCGAATGGGTGATCTTTGAGAACACGCAGCCGCCGATTGTAGAGGAAAGTGTATTTCTCATTGTGCAGAACATACGCAAATCCCGCCGCCGCCCCACCAAAATGGGCGATATGGGTATTTTCTCCGGGCTGCTTTATTGTGCAGAGTGCGGCGGTAAAATGTATCAATGCCGAGCAACGAACTTCACCGAAGAACAGAAATATTTTATCTGTTCAACCTATCGCAAAGGCAAAGACTTGTGTACGACCCATTCAATCAAAAATGTTGTTCTGTATGAAATCGTTTTGAAAAACCTACGGGAAGCAATCGACTATGTAACAGAGTATGAAGCCGAGTTTGTGCAGGAAGCAGCAGACAGCCGTTTGCGAGAGCGCGACGCAGAGTTTTCCTGCAAGCGCGAAACACTTTCCAAAGCCGAAAGCCGTATTGCCGAGTTGGATAATCTGTTTATGCATTTATATGAGGACAATGTAACCGGGAAATTATCTGACGAACGGTTTATCAAAATGTCCCATGATTACGAATTGGAGCAGAGCAATCTAAAAGCTATGGCAGAAGTGCTACGGGAAGAAATCAAGCAGCAGGAAAAACAAAAGACCAACGTTAAAGCGTTTATCAGCGCGGTAAAGAAGTACACCGATATGCAGCAGCTTGACGCTGCTATGCTACGGGAGTTTATAGATCGTATCGAAGTTTCCCATACCGACAAAAAATCCAAGACAAGGGAAATCACGATTGTATATAACTTCATCGGTGCATTTGATTTTGAACGGGCGAAAGAAAAAGCCCAAAATACAACGGAAAAACAGCAAAGAACGGCATAGCCGTTTGGCTACACCGTTCCTTGCTAAAATGTTTTCTTAATTCACCGCCCCATTTTGGGTAGCTGTTTTTTCTTCCTCACAGCAATCACTTAAGAAATGGCTGATCCAGTCGTTTTCTTCACGATAAGCGTTCATGGCATCTTGGACGCACTTTGGTGGTACCAGTTTGAAACCGGAAGAGATGTATCTTTTTGCTCCCGCAATCATCCACGAGAGAATTGCTCCGCCGCATCGCTCGGACAGCACCTTGGCATAGTTCTTAATTTCTCCCTTGGCACCCCTGAAATTTGCCTTTAGAGGAATAACGATCAGGCGGTCCCAGGTGCCTTTGTCGATGGTCCCGACTTTGGGCAGATGGTTGGTATAAAGCACCGTCGTATGCGTCGGGATGAAGTTAAATGGTGCTTCAAATTTTTTCTCAGCATGGATGGGATCTGTGCTGGAGAGATTTTTCAAAGAGCCTGAGTCGAGCCTTTTCCCTTCGGGTAGCTCGGCTGCGAGAATAAGCCTCTTGTTGTGTGTCTCGGCAAGCTCCGCACCTTTGTTCTTGGTCGGCTTTACGGTTAACAGCTCGGCGGAGATGGTACCGGCGTAGTCTCCTAAAACATAGAACTTGGCGTTATTGAAGGTGGATTTACCGTTTCCGCCTTCACCGTACTGGATCACAAGATTTTCATTTAAGACTTCTCCGATGCACTCTACACCGGATTCCAGCTGCAGGTAATCTTCGAGAGCCTTGTCTTTGCAGGTGAAATCACGAAGGAACCGGAGCCATTCGTCCATACCTTTGTCATTTGGTGATACAGCACAAATTTTGGTGCAGTAGTCCTTCGGATCATGCGTCCGCAATTTTCCGCTGCGAAGATCCACCGTCCCGTCCGGCGTGTTTAAGAGAAAACCGTCTTTATCAAGCATTTTCACATCGACTTGCACCATCGGTTTCAGCTCAGTGATAGTTGCCTTGATGTTGGAAGATTTCCGGCGGCTTAAGACAAACTTGTAGAAGGCTTCCGCTTTTTCCTGTGTTTCATCACTTTCCGCTTCATTCATCATTTTCCACGCAAGGCAGAGCTGCTTATGGGTAAATCCCTGCAGCGCTTTCTGCACTAAGAGGTCATCGTCTTTCCAGACTTTTCCCGTGAAATAATAGAGACCGAGACCTTTGACATAGATGACCTTGTCAGTAGCCGCTTCGAGAAAGGCTTTTGCCTGTCCGACATCGGTAAAGTCAGACGGGATGAGACTTTCTTCGAATTCCATGCTGTTGTATTCAGCAGGCGAGATATAATTTTTATCCGCTTTGATGGTGCTGTTGTAAAAACCGACTGCACTGTTCCAGATGCTGCTGAGTTCTTCTTCAGAAAGCGGAGGTGTGCATTTTTTTGCTTCCTCAAGATAGGCTTCATGCGCTTTATTATCATCGGTGCCATATTTCTTGAGCACAAGTCCTGCAAAATGGGACATGGTAGTGTTTCGCGCGCCTTCTGTGATTTTGGCATTGGCACGGCTCATAAATTCATCAATGCAAAAAGTACCATCGAAATATTCAACCTGTGGATTCTCAACACCGAAGAAGAAACGCGCCGCGTCAAGTGCACCATCATCGAAGGCGGGAAACCTTGCCCGCACTTTTTTCTTAAGGCGGTTATATAGCTTCGCATCGCTTATGGAAGTTTTCAGAGGAAAGTAGATGTGAAACTTGGGACGCGCGGCTTTTCCGTCCTTTTCCTTCATGTTATTTCGGGAATAAACCACAAAAAAGCGCACGTCAGGATAAGCCGCTTGAACATCTTTCGGGGTTTTCCACTCAGCAGGTGGAATATCTGAAGCTAATGGATCGGAAGATACGTTGTCACAGTCCAGCGGCAGACAGTCGGATTCCTGAAAGGTTTTATTGCTTCTGTAGCCTTTGATGAGCTTCTTGCGCTGGTTATAGCCATCCTTGTAAATCGCACAGACGTGATCAAAGGCAGCGACCTTTTTCAGGTCGTCTGCCGTTTTGATCTCTGCAATAAAGGGATAGCTTGTATTTGTTTTCTTGCCGCGAACATTCGAATAGCTGATTCTCATTCTTCAACCTCCTTCAAGTCCTCGGTGAAATAGCGAACGTTTCGCCTGTGGTATTTGGCATATCCGATCTCTTTGGTCATACCGAGAGAGGGTTTTCCAAATGCCCAAAGCTCGGTGCATTTGTCGATCAGGATTTGTCCGAAGAAAAGCGCCAGCTCACGTTCGCTTTTCTCATCCATGAACTGCGGATACATGAGATGGGGCACGATTGGGATAAAGCCTTGATCAACGGCAAAGCGGGCATAGCGCTTGGCGGCTTCGGTGTTTTTCTCAACATCTCCAGCATAAGGAGAGGCGATATAGACAAGCGGCATATAAGGATAGCGATGCGTCTTAAAGATTGCTTCATAGGCGGTCGGATCCGCGTAGCCTTCTGCGTTTTGATATAGGTTTTCCATCAGCGCACCTCCTTGATTTGTAGTTTCATGGCATACCATTCGAGGTAGCGTTTTCGTTGCTGAAAATCAGGGACGGCAACAAGCAGTCCGACATCGACTTTTTGCAAAATGTTGAGCATGGAGATTTCATCTTGCGAAAGATACGGACGTATGGATGTTCCTTTATCGATGCCGTGTACTTCTCGGTAATGCTTGGCATCCATGCCAAGCACGATGCGGTTAAGCATATTGCATTCGTTCGAGTAGTGATATGGTTTCGGGTTGTCATGGAGAAGCTGGATGTTTTCCGTCAGCAGTGGGAACTCCTGTCTTGCCGATACCAGCGTTTTGATGAAGGTTTCCATTTCGTTGAAACGCTTGATATAGAGTTCTTTGAACCGCATTGCCTTTTTGCCGGTGTATCCCATTGCCAACATGGTGAAACCATCACGAGTTAAGTAGTAACAGGGCAGTTTTCGTCCGGTATTGTCCTTATAACTACTGAGCTCAAAATTGAGCTTAACAAATTGTTCACTCAATCCAGATTTGGATTCAGTGAGTTTTTGAATGTCGCGCAGGATATGGAAGTGTTCTTTCTCGAAAAATTGCGCAATTGCTCTTGAATCGACACGAGCTGTGTCATGGTTGTCTGCGAATACTCCGTATTCGTCTTTTGGAATTAGTTCTTGCATTAAAAACCTCCGTTTCTACAGATGGAGGGAGCACCATTGCTGCCCTCATCACTTCCTGAAGAAACGGAGATGGTTTGGACGAACTTTTTAGAGAAAATAAAAAACATGCCACTGCTCAGATTGCTAAAACCGCAAAAGGAGGTAGCGAAAAGTGACACCCTTGAAAACTCAATAACAAAGTGTTATTGAGCAGCATCGCTCTCATAGAGTGAACGAAACGTTCACTCCCTTAAAACAATCTCGACTACCGTTTTGGTAGCCGAGACTTTTTAATCTTTCTTGTAAAACTCGCACTCATAGCCGTCGGCTTTGAGCGGCAAGCCTTCAGCCCACGGCGGCGTGCGGCTCATCTGTTCACAGACTGCATCAAGGGACATACGAGGATCGGCTTCAATCACGACCTCATCATGGATATGCATAACAATCGAGCAGTTATGAAGTGTCCGCATGGCATAGGCCAAGATGTCACGAGCAGTTGCCTGCACGATATTTTCCACGAACTTTGGACCGTAGGAGTCAATGCGATCCCATTTCTTTCCGGTGATGACACCCTCATAGGTGACGCAGGGAGATCCGAAGCGGTTCTCATCGAGCTTTGGTTTTACATAGGCTAAGGCCCTTCCGGAGGGCAGCATGATGAAGAGCATGCCGGAACGGCAGCGAAAGGTGAGACCGTGTGTCTTGGTGACTTTCTTATGGCGGACAGCTTCAAGGATGGCACGATCCACGTCCCACCAGAATCTGACGATCTTCGGATTGGCAGATCGCCAAGCATCAACGATGGGTTTTAATTCTTCTTCGGAAAGTCCCATCTCAAGCGCGCCCATCGCTTTTAAGGCTCCGATCGAGCCGCCATAGCCACAGGCCAGTGTTGCTATTTTCCCTTTTTGGCGGAGTTCTCCATTGATACCGTGTTTAACGACGGGTACCCCGAACATTCGCGATGCCGTCTCGCAGTAAAGGTCTTTTCCGGCTACAAAGGCATCGAGGGAATCTTGCTGCCCTGCGTACCAGGCGATAACCCTGGCTTCAATGGCTGAGTAGTCGGAAACGATGAACTTATGACCTTCCTTTGGAACAAAAGCGGTCCGTACCAGCTGGGATAAGGTGTCCGGTACATCTTCGTAGAGGAATTTAACAGCTTCAAAATCTCCTACTCTCACCAGCGCTCTGGCAGCGCCAAGATCCGGCAGGTGGTTTCTGGGGAGATTTTGCATTTGCACGAGTCTTCCTGCCCAGCGCCCTGTACGGTTGGCCCCGTAAAACTGAAACATGCCACGAACTCTGCCATCTTTACAGGCGGCATTTTGCATCGTCTGATATTTCTTAACCGAGGATTTGGCAAGCTGACTGCGAAGCATAAGAGCATCCCGCAGCTTAGGCGGTGCGGTTTGAATCAGTTCTGCGACTTGCTTTTTGCCGAGCGACTCCGTGGGCATACCGTTTTGGGCAAGCCAGTCTTTCATCTGAACGACCGAATTCGGATTCTCCAAGTTAGTGATGGCTTTCATCTTGGTGATGAGCTCATCCTTTGAGCGCCTGTCCATCTCAACGGCTGCATTCGCTAAAGTAAGATCGACTTTCACGCCGCGGTCGTTAATCTCCTGATCAATGGCGTATTCGTCCCAGAGAAAATCCGGCACAGGGTAATTTTTGAGCCTCTCTTTGATGGAAAGTTCCACCTCGACATCGCGCTTGTTGTAGGCCTTGAAGGTTTTCCACATGTCCGGTGCATCAGAGGGAAGATGTCGTTTTCCGGTTTGCCTGTCCGGCATGCAGAAATATCGGATGAGGTCTTTACCTTCTTTCATCTTTTGATTTTGAAGGCCGAGTACTGTACCGACACCTTCCAGTGATAGTGGAAGACCCAAAGTTGCTGCCCAGACCATCGAACAGCGCCAAGAGGCGGGATTAAGAAATCTTGCCATCTCTGTTGAAAGCGGATGATGGTCATGAAAGGGATCAAGGCTTATGCCGATATCCGATAGATAGCGAGATAAACAAACTCTCTCAAAATTCGCGTTATATGCCCATTTAATAACGGTGTCGTCTGTCAATGCATCCAGAATGACGTTGGGGATTTGTTCGCCTTGTGCAAGGTCGATGACCCGAACTTCACCGCCATCGATCGAGCAGCCGAAGAGCAGAATGTTAAAATCAGGCGCTTCGGCGTACTTATATACGCCTGCTTTGGCCAGTTCAACGGACGAAAATGACTCTATATCAATGCTAAGTGTTTTCAAAATTTCACCTCCTAAATGGCAGAAAGGCAGACTGCATCTCCAGTCTGCCTCTCCGCATCATTTGCTTTTAACGGGTTGTGGTGTCGTTCTTTTTCTTCTCGCGCTTTTCAAGCCTTGCAATGAGCACGTTGGCAAAGGCGGCACCGAAGGTGAATCCGACAGCCATCGATAAGATGAGCTGGCACATGAAATCAAGTAGATTTGTCATGGCACACCTCTTAGCTCAAGAAGTCATCGTCATCATCGGTTGCAAAGTCTTCTGCGGCAGAAGCATGACCGCCGAGCGGCTCGCCGTCACGGATTTTCTGCAGGTTGTTGAGACCACAGGCGATGCCGCGATTTCCGTTGGAGTTGAACGCATAAAAATTGATGGACGCGCGGCCGTAAACGCCTGAGTAAACTTCGGAGCTGTCGATGATTTCATTTCGGTCGGCATCGACGATGCCCGGCTTGGTGGTGGAGTTGGCATTTACAAAATAACTGTTTGCATACGCCTCATCGTCCGGACGTTCAGCATCTCCATCACGAAGCGGCGTTTTGATTGCCGCAAGTGCGGGTACCGAGCGGCCGTTTCCTTTGAGTTTGGCTTCACCTTCCTTGTAGGCGGCTTCGATGGCAGCTTTGATTTTCCCTAAAGTGACGGTATCGGACTTGGGGATAATGAGCGAAACGCTGTACTTCGGTGTGCCGCCGTTGATGGATTTTGGCTGCCACACGTTGGCATAACTCCAGCGAGTGTCTTTTCCTGTGATAACCTTCATCGGGTTTGTAAATTTTGACATTTAATTTTCCTCCTTAAAATCTTCTTTTGCTGAATTCATGGCCGGACGTTTATCGGACTCCGGCACGAGGGTTGGTTTTCCTTGCGGCTTTTCAATTAAGCCTTCAAGCAGCTCCTCAAAGCGGTTTTTGCCTAAGAGCTTGGTCATAGCGGTGATGCCGAGGAGCTTTTCCTCATAAGGATTAAAGCCTGCATCGGATACCTTCTTTGCGACGGCATCTTCGTTTACGTATTTACGGTTGCTTCTTCCTGCGACGAGCTTATATCCGTACCACTCTTTTCCTGCCACTGCACGTGTCAGGGCATAGGCCTTGATGTCTTCCGCCCAGCTTGTAAGTTCATCAAGAAGAGGCAAAATCGCTTCGATGTCCGCATCGGTTAAGGTAGGCGGAAGGGCAAAGTCATATCTTGCCAGCGCGAGATTGGCTTCCGCTCTGGCTCGGCAGTCGGCCTTTGCCTTGCAGAAGCGGCAATGTTCGCCGGCTGTAAAGTCGCCTTTACCTTCGGCGGCAAGTTCCGCCTTTGGTTTGAGTGTGTTCTCTGCCCAGTCCAGCAGATCCGATGCTTTCATCTCAAAGACGGATACGCTGTCACGCCGTGGCTGAAAGATCGTCATCGATACGGTCTCAATGTCATAGAGCGCAGAAAACATCTCATAGGCCCCGAGGGCATAGCACATGAGCTGCGGATTATGATCGGCTTCAACGAGCACGCCCTGTCCATATTTGAGATCTGTGATGGAAAGCTTGCCGTCGGCGATGATGAGGGCATCGGCAGTACCAAAACCATCCGGTACATAGGTGGAAAAGTCCACACGCTGTTCCACCAGAACGATTGGATCAATCGTTGCCTTTTTAGCTTCGGCGACTTGCTCCAGCACGTAGCCGGCATAGGCATCGGTCGCTTCATCCATTTCCTCGTTAAAATAATCAAGATTCTCCGTCGGATCATCGGCTTTCCTGCCTAACGCTTTCAGCACCTTGTACTCGGCAAGAGCGTGCGCCGCGGTGCCTTCTTGTGCATAAGAGCTTGACGTGTCCTCATACTTTGCCGAAAGCAGAGCCGAGGGCGGACAGGCAAGCCAGCGATAGGCACTTGATGCGGAAAGCAGCGCATGTTTAGCCTTCATGTAGCACCTCCGCATCACGAAGCAGTGCTTCGTAATTTTTCGGATCAACTTTAGAGAGTCTGTCCGCGCCGTACTTTTCGATCAGGGCGCGCACTTCTGCGGTGTGACCCGCACGGGAGATGTCCGCTAAGACGGCCCGCACGTCTTCAAGCTTCAGCTCCGGCTTTGGCGTTTTTGCAGGAACCGTCACTTCTTCCGGTGCCGTGCTGAACATCGCTTCCAGCTCGGCAGCGATATCGCTTAGTTGTTCGCTACAGGAATGTAGGTCGTCTATAACAGCTTTCATCTTTTTCATTTGTCCCATAAGGATTGCCTCCTTTCTTTGTCTGAATCAGTTTTCTTGTCAGGTCTTTGGTGATAATTGATATGGCAGAGAGCACTTCGATGAGTTCTTCTCTTGTCACACCCGGCACATTGCTTTGTGGTCTCATGGCTACCTCCTTTCCTTCGGGGCCTGCCGTTTTGCCCCTCTATCCCTCCCTGAAGAAAGGGAGGGACGTTGGACGAAGGTTTAAGGTTTAGGAATAAGAGATGAGATCCAAAAGAAGGTCACGAAGCTCCGGATGCCGGCTTTTCAGCCGAGCAAAAAGCTGACGTTTTCGGTAGTTCAGTGTGGTACGTTTGATGCCGAGGATTTCTGCCATGTCGCGCTCGGATTGACCGGCGACAACAAGACGGATGATTTGGCGCTCCTCGTCCGTGAGACCTGCGAAAATACGGCTGAGTTCTTCGCGCAAAGTTTTACGCGCAAGGACGCCTTCCGGTGAATACGCTTCCGATGCAGGAAGCACATCGGCGTAGGTAAGCGCGCTGTCTGTTTGTACGGTGTCATGGATGGAGACAAACTTCCCGGCAGAACGAAATGGACAGCCGACGCATATGCCATCGCAGCGGTTGATGTTTGCCTTGGTGACGTGGCATTCGCCGTGATACTGCATCTTCATGCGGATACGGGCGCATTCGTTCTCGTAGTCTTTCTTGTGTTCAGGGCTTGTCTCGACCAGACCGAGACCGCGAATATAAATCTTTGATACATGATTTTCTTTCTTTGACATTTCTTGACTCCTTGTCCGCCTGACTTGCGGTTAAGGAGCGAGGAAATGAAAAGAGCCGGTGCATTTTGACACCGACTCTTGAACAGACAACCTGAAAATAGGGCGCAGAAAAGAGAAGGTGTGAAAAACGCTTGTTTCAGGCCTTTCGACCTAAAATAGTTCTTTTCAAACCCTCGCCCTATTACGTAATTCAGGCTTAGATTTAGTTTTGAATGGAACAGTTACGTTCCCGTGATACGAGTTGCCCCGAAGGGCTGGCAGATGGGGTGTTCACACGTGAGAACAGATCATCATCCGCCTAATGCAATGATTACTTGCGTTTGCTTGGCTTCGTCTGCGCCAGAGCGCTTCCGGCTACAGCTTTGGACGTCTTGCTGAAGCGACCGTCGCGTAAGACAGTTGATGCCTTGCGAGCGATCTTCGCTGATGTCTGCTTGGTGTTTCTCGCCAT

Protein sequences of DBSCAN-SWA_2

>NZ_LT632322|527613:539733|539592_539733_-|WP_172619973.1|DBSCAN-SWA
MARNTKQTSAKIARKASTVLRDGRFSKTSKAVAGSALAQTKPSKRK
>NZ_LT632322|527613:539733|538478_538658_-|WP_162272130.1|DBSCAN-SWA
MRPQSNVPGVTREELIEVLSAISIITKDLTRKLIQTKKGGNPYGTNEKDESCYRRPTFL
>NZ_LT632322|527613:539733|529016_529169_+|WP_157885023.1|DBSCAN-SWA
MKQSDKLTAYYVCAVHKTDTLYLDNQMQRLLYHAAPNGYAALTAKGGERK
>NZ_LT632322|527613:539733|530971_533005_-|WP_071705130.1|DBSCAN-SWA
MRISYSNVRGKKTNTSYPFIAEIKTADDLKKVAAFDHVCAIYKDGYNQRKKLIKGYRSNKTFQESDCLPLDCDNVSSDPLASDIPPAEWKTPKDVQAAYPDVRFFVVYSRNNMKEKDGKAARPKFHIYFPLKTSISDAKLYNRLKKKVRARFPAFDDGALDAARFFFGVENPQVEYFDGTFCIDEFMSRANAKITEGARNTTMSHFAGLVLKKYGTDDNKAHEAYLEEAKKCTPPLSEEELSSIWNSAVGFYNSTIKADKNYISPAEYNSMEFEESLIPSDFTDVGQAKAFLEAATDKVIYVKGLGLYYFTGKVWKDDDLLVQKALQGFTHKQLCLAWKMMNEAESDETQEKAEAFYKFVLSRRKSSNIKATITELKPMVQVDVKMLDKDGFLLNTPDGTVDLRSGKLRTHDPKDYCTKICAVSPNDKGMDEWLRFLRDFTCKDKALEDYLQLESGVECIGEVLNENLVIQYGEGGNGKSTFNNAKFYVLGDYAGTISAELLTVKPTKNKGAELAETHNKRLILAAELPEGKRLDSGSLKNLSSTDPIHAEKKFEAPFNFIPTHTTVLYTNHLPKVGTIDKGTWDRLIVIPLKANFRGAKGEIKNYAKVLSERCGGAILSWMIAGAKRYISSGFKLVPPKCVQDAMNAYREENDWISHFLSDCCEEEKTATQNGAVN
>NZ_LT632322|527613:539733|538216_538531_-|WP_057002192.1|DBSCAN-SWA
MGQMKKMKAVIDDLHSCSEQLSDIAAELEAMFSTAPEEVTVPAKTPKPELKLEDVRAVLADISRAGHTAEVRALIEKYGADRLSKVDPKNYEALLRDAEVLHEG
>NZ_LT632322|527613:539733|533402_534074_-|WP_022866306.1|DBSCAN-SWA
MQELIPKDEYGVFADNHDTARVDSRAIAQFFEKEHFHILRDIQKLTESKSGLSEQFVKLNFELSSYKDNTGRKLPCYYLTRDGFTMLAMGYTGKKAMRFKELYIKRFNEMETFIKTLVSARQEFPLLTENIQLLHDNPKPYHYSNECNMLNRIVLGMDAKHYREVHGIDKGTSIRPYLSQDEISMLNILQKVDVGLLVAVPDFQQRKRYLEWYAMKLQIKEVR
>NZ_LT632322|527613:539733|527613_528051_+|WP_055219620.1|DBSCAN-SWA
MELSSSDKERIQHQYDALAKKTLVGEAKSYRRTLAKRAAREVTFSDLSESELAQLFTTDEYESDYYRFQVSGFDVLVKNELLAEALNALPERKRDIVLLSYFLDMSDAEIGELLNVVRTTVFRHRKSALAKIKQYLEGKADDEHR
>NZ_LT632322|527613:539733|534343_536317_-|WP_071705131.1|DBSCAN-SWA
MKTLSIDIESFSSVELAKAGVYKYAEAPDFNILLFGCSIDGGEVRVIDLAQGEQIPNVILDALTDDTVIKWAYNANFERVCLSRYLSDIGISLDPFHDHHPLSTEMARFLNPASWRCSMVWAATLGLPLSLEGVGTVLGLQNQKMKEGKDLIRYFCMPDRQTGKRHLPSDAPDMWKTFKAYNKRDVEVELSIKERLKNYPVPDFLWDEYAIDQEINDRGVKVDLTLANAAVEMDRRSKDELITKMKAITNLENPNSVVQMKDWLAQNGMPTESLGKKQVAELIQTAPPKLRDALMLRSQLAKSSVKKYQTMQNAACKDGRVRGMFQFYGANRTGRWAGRLVQMQNLPRNHLPDLGAARALVRVGDFEAVKFLYEDVPDTLSQLVRTAFVPKEGHKFIVSDYSAIEARVIAWYAGQQDSLDAFVAGKDLYCETASRMFGVPVVKHGINGELRQKGKIATLACGYGGSIGALKAMGALEMGLSEEELKPIVDAWRSANPKIVRFWWDVDRAILEAVRHKKVTKTHGLTFRCRSGMLFIMLPSGRALAYVKPKLDENRFGSPCVTYEGVITGKKWDRIDSYGPKFVENIVQATARDILAYAMRTLHNCSIVMHIHDEVVIEADPRMSLDAVCEQMSRTPPWAEGLPLKADGYECEFYKKD
>NZ_LT632322|527613:539733|537099_538227_-|WP_071705133.1|DBSCAN-SWA
MKAKHALLSASSAYRWLACPPSALLSAKYEDTSSSYAQEGTAAHALAEYKVLKALGRKADDPTENLDYFNEEMDEATDAYAGYVLEQVAEAKKATIDPIVLVEQRVDFSTYVPDGFGTADALIIADGKLSITDLKYGQGVLVEADHNPQLMCYALGAYEMFSALYDIETVSMTIFQPRRDSVSVFEMKASDLLDWAENTLKPKAELAAEGKGDFTAGEHCRFCKAKADCRARAEANLALARYDFALPPTLTDADIEAILPLLDELTSWAEDIKAYALTRAVAGKEWYGYKLVAGRSNRKYVNEDAVAKKVSDAGFNPYEEKLLGITAMTKLLGKNRFEELLEGLIEKPQGKPTLVPESDKRPAMNSAKEDFKEEN
>NZ_LT632322|527613:539733|528762_528924_+|WP_147659365.1|DBSCAN-SWA
MKQTTKSPVVREYKIGDITYIVKAVVKDGVKEDAATKVRRLIQNDLNRGKSPV
>NZ_LT632322|527613:539733|538745_539282_-|WP_071705134.1|DBSCAN-SWA
MSKKENHVSKIYIRGLGLVETSPEHKKDYENECARIRMKMQYHGECHVTKANINRCDGICVGCPFRSAGKFVSIHDTVQTDSALTYADVLPASEAYSPEGVLARKTLREELSRIFAGLTDEERQIIRLVVAGQSERDMAEILGIKRTTLNYRKRQLFARLKSRHPELRDLLLDLISYS
>NZ_LT632322|527613:539733|528034_528277_+|WP_003431293.1|DBSCAN-SWA
MMNTVRKSENLLPFPVISAAANGDTNAMCAILKHYEGYIAKLCTRTLKDDAGNTYSYVDEEMRNRLQVRLITRTLAFHVG
>NZ_LT632322|527613:539733|529165_530935_+|WP_083428150.1|DBSCAN-SWA
MTKTFSFQQIAVPKVLSEEVREAISNNVLQFYVRDQQQEAQDEGITALYERLSQEDKLDGESNSIANQKKILERYCREHGITAYRHYDEDDGYSGTNFNRPGFQRMLADIKAGKIKRVIVKDMSRFGRDYLQVGFYTDMLFPDFGVHFIAVNDGVDSTRGENEFTAIRNVFNEMYARDTSKKIRATWQSKGKSGEHLTTIPPYGYMKDPNNKKKWIIDEEAAAVVQQIFALCVSGMGPTQIAKWLEKSEILNPTFYWLSKGMKVGNKPKPGANPYKWTNETVSRMLEKIEYLGHTVNFKTRKQSYKSKKKLWNDPSEWVIFENTQPPIVEESVFLIVQNIRKSRRRPTKMGDMGIFSGLLYCAECGGKMYQCRATNFTEEQKYFICSTYRKGKDLCTTHSIKNVVLYEIVLKNLREAIDYVTEYEAEFVQEAADSRLRERDAEFSCKRETLSKAESRIAELDNLFMHLYEDNVTGKLSDERFIKMSHDYELEQSNLKAMAEVLREEIKQQEKQKTNVKAFISAVKKYTDMQQLDAAMLREFIDRIEVSHTDKKSKTREITIVYNFIGAFDFERAKEKAQNTTEKQQRTA
>NZ_LT632322|527613:539733|533001_533403_-|WP_022866305.1|DBSCAN-SWA
MENLYQNAEGYADPTAYEAIFKTHRYPYMPLVYIASPYAGDVEKNTEAAKRYARFAVDQGFIPIVPHLMYPQFMDEKSERELALFFGQILIDKCTELWAFGKPSLGMTKEIGYAKYHRRNVRYFTEDLKEVEE
>NZ_LT632322|527613:539733|536384_536525_-|WP_157885024.1|DBSCAN-SWA
MTNLLDFMCQLILSMAVGFTFGAAFANVLIARLEKREKKKNDTTTR
>NZ_LT632322|527613:539733|536535_537099_-|WP_071705132.1|DBSCAN-SWA
MSKFTNPMKVITGKDTRWSYANVWQPKSINGGTPKYSVSLIIPKSDTVTLGKIKAAIEAAYKEGEAKLKGNGRSVPALAAIKTPLRDGDAERPDDEAYANSYFVNANSTTKPGIVDADRNEIIDSSEVYSGVYGRASINFYAFNSNGNRGIACGLNNLQKIRDGEPLGGHASAAEDFATDDDDDFLS

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_055219620.1|527613_528051_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.2e-26	46.6
WP_003431293.1|528034_528277_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_147659365.1|528762_528924_+	hypothetical protein	NA	NA	NA	NA
WP_157885023.1|529016_529169_+	hypothetical protein	NA	NA	NA	NA
WP_083428150.1|529165_530935_+	recombinase family protein	D2XR37	Bacillus_phage	3.9e-21	25.4
WP_071705130.1|530971_533005_-	primase C-terminal domain-containing protein	A0A1B0RXC5	Streptococcus_phage	2.7e-143	40.4
WP_022866305.1|533001_533403_-	hypothetical protein	A0A2K9V2W4	Faecalibacterium_phage	9.3e-16	48.0
WP_022866306.1|533402_534074_-	Rha family transcriptional regulator	A0A2K5B268	Erysipelothrix_phage	4.2e-93	72.9
WP_071705131.1|534343_536317_-	hypothetical protein	A0A2K5B2B0	Erysipelothrix_phage	2.6e-252	63.0
WP_157885024.1|536384_536525_-	hypothetical protein	NA	NA	NA	NA
WP_071705132.1|536535_537099_-	DUF2815 family protein	E4ZFK3	Streptococcus_phage	4.3e-75	77.1
WP_071705133.1|537099_538227_-	DUF2800 domain-containing protein	A0A1X9I6D8	Streptococcus_phage	6.1e-121	59.7
WP_057002192.1|538216_538531_-	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	2.1e-10	39.0
WP_162272130.1|538478_538658_-	hypothetical protein	NA	NA	NA	NA
WP_071705134.1|538745_539282_-	hypothetical protein	NA	NA	NA	NA
WP_172619973.1|539592_539733_-	hypothetical protein	A0A0A8WJA8	Clostridium_phage	8.8e-06	60.9