CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT632617	Legionella pneumophila strain ST42 isolate ST42 chromosome 1	1 crisprs	DEDDh,DinG,cas3,csa3,WYL,PD-DExK	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT632617_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT632617_1

1581223-1581343

Orphan

Consensus_repeat	Method
CCTGGCAGCAGCGCTGATCAGCATTCCAAAAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT632617_1

>merge|NZ_LT632617|1|1581223-1581343|CRISPRCasFinder
CCTGGCAGCAGCGCTGATCAGCATTCCAAAAAGCGTCACCACGCTTAACTTGAGCGACAATGGCCTTTATCAACTAAGCGCTGATCGCCTGGCAGCAGCGCTGACCAGCATTCCAAAAAGC

>NZ_LT632617|1|1|1581223-1581343|CRISPRCasFinder
CCTGGCAGCAGCGCTGATCAGCATTCCAAAAAGC	GTCACCACGCTTAACTTGAGCGACAATGGCCTTTATCAACTAAGCGCTGATCG
CCTGGCAGCAGCGCTGACCAGCATTCCAAAAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT632617.1\|WP_038838504.1\|1588034_1588787_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_LT632617.1\|WP_040147683.1\|1574476_1575901_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT632617.1\|WP_038838490.1\|1575971_1576649_-\|RES-family-NAD+-phosphorylase	unknown	unknown	gnl\|CDD\|378053
NZ_LT632617.1\|WP_038838502.1\|1586836_1587784_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
NZ_LT632617.1\|WP_038838488.1\|1572718_1574002_-\|Dot/Icm-T4SS-effector-LegL2	unknown	unknown	gnl\|CDD\|238064
NZ_LT632617.1\|WP_038838510.1\|1589376_1590333_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|377252
NZ_LT632617.1\|WP_038838495.1\|1582273_1583527_-\|glutamate-5-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|234685
NZ_LT632617.1\|WP_038838507.1\|1588852_1589380_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LT632617.1\|WP_038838512.1\|1590336_1592118_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LT632617.1\|WP_011213883.1\|1576650_1577025_-\|DUF2384-domain-containing-protein	unknown	unknown	gnl\|CDD\|378249
NZ_LT632617.1\|WP_038838497.1\|1583535_1584606_-\|glutamate-5-kinase	unknown	unknown	gnl\|CDD\|235460
NZ_LT632617.1\|WP_038838493.1\|1578134_1580450_+\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|366019
NZ_LT632617.1\|WP_027265288.1\|1577237_1577897_+\|methyltransferase	unknown	unknown	gnl\|CDD\|226608
NZ_LT632617.1\|WP_038838480.1\|1567005_1567731_-\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|182294
NZ_LT632617.1\|WP_038838514.1\|1592110_1593571_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_LT632617.1\|WP_038838482.1\|1567790_1569809_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|236864
NZ_LT632617.1\|WP_027265292.1\|1584791_1585217_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LT632617.1\|WP_038838500.1\|1585505_1586486_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT632617.1\|WP_038838487.1\|1571285_1572347_-\|Dot/Icm-T4SS-effector-Lem11	unknown	unknown	unknown
NZ_LT632617.1\|WP_038838484.1\|1569801_1571121_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181265

Protein	Function_ID	Function_description	E-value
NZ_LT632617.1\|WP_038838504.1\|1588034_1588787_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.1939e-48
NZ_LT632617.1\|WP_038838490.1\|1575971_1576649_-\|RES-family-NAD+-phosphorylase	gnl\|CDD\|378053	pfam08808, RES, RES domain. This presumed domain contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. The domain is found widely distributed in bacteria. The domain is about 150 residues in length.	4.85625e-30
NZ_LT632617.1\|WP_038838502.1\|1586836_1587784_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	1.74719e-39
NZ_LT632617.1\|WP_038838488.1\|1572718_1574002_-\|Dot/Icm-T4SS-effector-LegL2	gnl\|CDD\|238064	cd00116, LRR_RI, Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).	1.39347e-05
NZ_LT632617.1\|WP_038838510.1\|1589376_1590333_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	1.89334e-73
NZ_LT632617.1\|WP_038838495.1\|1582273_1583527_-\|glutamate-5-semialdehyde-dehydrogenase	gnl\|CDD\|234685	PRK00197, proA, gamma-glutamyl phosphate reductase; Provisional.	0
NZ_LT632617.1\|WP_038838507.1\|1588852_1589380_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.80826e-09
NZ_LT632617.1\|WP_011213883.1\|1576650_1577025_-\|DUF2384-domain-containing-protein	gnl\|CDD\|378249	pfam09722, DUF2384, Protein of unknown function (DUF2384). Proteins in this family are found almost exclusively in the Proteobacteria, but also in Gloeobacter violaceus PCC 7421, a cyanobacterium. The function is unknown.	0.000399459
NZ_LT632617.1\|WP_038838497.1\|1583535_1584606_-\|glutamate-5-kinase	gnl\|CDD\|235460	PRK05429, PRK05429, gamma-glutamyl kinase; Provisional.	2.96735e-128
NZ_LT632617.1\|WP_038838493.1\|1578134_1580450_+\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|366019	pfam00311, PEPcase, Phosphoenolpyruvate carboxylase.	3.29507e-55
NZ_LT632617.1\|WP_027265288.1\|1577237_1577897_+\|methyltransferase	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	4.77584e-17
NZ_LT632617.1\|WP_038838480.1\|1567005_1567731_-\|L,D-transpeptidase-family-protein	gnl\|CDD\|182294	PRK10190, PRK10190, L,D-transpeptidase; Provisional.	7.8536e-46
NZ_LT632617.1\|WP_038838514.1\|1592110_1593571_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	4.3974e-78
NZ_LT632617.1\|WP_038838482.1\|1567790_1569809_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	8.56043e-164
NZ_LT632617.1\|WP_027265292.1\|1584791_1585217_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	8.55898e-12
NZ_LT632617.1\|WP_038838512.1\|1590336_1592118_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.81623e-132
NZ_LT632617.1\|WP_038838484.1\|1569801_1571121_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181265	PRK08170, PRK08170, acetyl-CoA C-acetyltransferase.	0

>NZ_LT632617.1|WP_038838493.1|1578134_1580450_+|phosphoenolpyruvate-carboxylase
MKENVSHLPRELSRMVFWSLTCLKKAIAEVYGKETYERIEQIRLSMQDTIGSESFSLGKALHSLQIELSKLEKKQLYQIAHGFSLMMELINTCENAYRIFRINQRKEQVYSDMPQGIHYVLTAHPTEARTNEFLKLFKEIRDYLIEVLKSPYLMNEPHLDQMLKISLQINISYHEKPSVEDEAQYIYQYALHPLNIKLYHSFLAKGVPIQLRTWVGGDKDGHSGVNEKIMLKSLELSRSFFIAYIQECLEEVLEIIKLSTALGKNKSLADQINQLVKKAYGLKKIQSKDHEKISAFKNELTATQINALKFLNFEPEQFSIISSIFHLYPALVMPIELREDSTIVKESLTSIKKTTITKMLEQVHSITHGTDPKNYIRGFILSMVESAEDIKNGINLVKKVFKSYALPVVPLFENQLALTNADTILNNSITEDIRQKHLKQWEGNYEVMLGYSDSSKENGVLPSRLMIAKSLKNIQSTLENKNLQPIFFHGSGGSIERGGGDIKEQTASWSKEMMSNYKVTVQGEMVARLFGSSSILKSQIDKFLDIYSQKGKSNDNDYPEELSLFSTRVSQKYKTLIQSDWFWQIVEQASPYHFLKELKIGSRPTKRKSGPDQRKLRAIPWILCWTQTRLLFPTWWGIGSTWSELNGIEKNRLKALYKENALFAAFVKQLGVTLSKVYLPVWEHYLLQLTGSIEYLKPFQSELESTIQFFYQITDEKDFCFHQPWLGESIQLRSTLIHPLNLIQIEAMKRKDLPLLRKTVTGISCGMLTTG
>NZ_LT632617.1|WP_027265288.1|1577237_1577897_+|methyltransferase
MIDTIQSEPKINFTYNYKQPDDYHFSLDSIHLAKFVAKQLESYPDLGSLRVLDLCAGCGVIGIELSWYLQAIRQIDFIEIQDIYTKYFYQNIANVNRPELQFRWHLLNYDELHKKKWEDKFDLIISNPPYFQPGHGMLSPSKFKNRCRFYLDSSFQSYIQALGNSLANRGKAYFLLRPLKHHGLDLFSDIQKILQETSVIATKISHIRGTDIILLEKLK
>NZ_LT632617.1|WP_011213883.1|1576650_1577025_-|DUF2384-domain-containing-protein
MQTNTRSLQSIPDEVVWKSLTNLVERFDLKESEARILMGDMPRSTYTSHKAKLNRDQKERVSYLLGIYKSLRILFEDGEQARTWINRKNDLPPFKGLTPKEYMLEGGMVRLADVRKFLDFWRGY
>NZ_LT632617.1|WP_038838490.1|1575971_1576649_-|RES-family-NAD+-phosphorylase
MYSYIDFNDKVHRLIPSKFPPVTLFDWADSAEELEQIALLEGLTNERILSELGKINLIDQEDWIGGPGSTPIMAAFTHTGFESRFSDGSFGIYYAASSLETAIKETCFHRERFYSASNEKPCSISMREYVANIKKPLIDITDKSYKDLFNPDPACYSKSQEFGKKICEKKEWGLLYPSVRDLNGLCVAVLRPPALTIPIQGCHLRYIWDGEKISDIYKESKITNI
>NZ_LT632617.1|WP_040147683.1|1574476_1575901_+|hypothetical-protein
MIVIFVHGWSVTHTNTYGELPQWLENQSKQGKLDIQVGNIYLGRYISFDDTVTVDDIARAFDQAVRDEIADKVKDGQRFACITHSTGGPIVRKWMDLYFKNNLAKCPLSHLIMLAPANHGSALAQLGKSRLGRIKSFFEGIEPGKCVLDWLELGSDMSWQLNESWLDYDCTANGVYSFVLTGQKIDRQLYDAVNSYTGESGSDGVVRVAATNMNYSLLKLHQEGDNGESLVVAKMTRTQPMAFGVLPGLSHSGKNIGIIRSITMANAATHPTAIWVLRCLQVKSRDSYNKLVKELDNITKETQKNEHKEFVKTLVFTREYITNRYSMIIFRLIDDRGNHLLDYDLYLTAGPQYSEQALPAGFFVDRQRNLNNRGKLTYFLDYDIMEGGINTPKMQGNLGFRVKAYPESSEQALAYYRLLDFHSSLADIHKILHPNETVMVEIMLQRRVDRTVFRINNNLTPAKISGKPTGKKID
>NZ_LT632617.1|WP_038838488.1|1572718_1574002_-|Dot/Icm-T4SS-effector-LegL2
MRVELFNPSIKKIIVKLSQLKGLWIVQLNLSKNRLSEKKFTDLVVLLSMLKAFGVTYLNLHFNNLGQKTGTELVALFKILKDSGISRLSLSANELYQKTGTELATLLTVLSDSNIIQLDLSCNWLGQRPDVELIELFKAWSSTPIIDLDLANNDLGKKSGSVLSEMFRALKVSLISHLGLRNNDLYQRTGAEFSSLLSAIKESPITHLDLSDNGLHLMVAAFETLFDALKDSSVTHLNLCRNGIGHLDMFQMTAMFCSLQCTGVTHLDLGENSLELMTAEELAAIFQVFKDSRLIHLGLNDSYLNNRTTEDLHLIFNALPANIATIKLSLEELTEMSSKQRQTIQRRFPRAEQVILVNNVEGRELNPSLSLGDANVYRRLGFVGASPPSLAGLASFFMVSNNLRFTREVQKLLPDEVTERIVKNILG
>NZ_LT632617.1|WP_038838487.1|1571285_1572347_-|Dot/Icm-T4SS-effector-Lem11
MWYDTLLEYLSETICPSNKEKARLFISHLFKLLKENSDFGENFEPEFIFGVMVALYNYSISHENRNVTLDEFGKYCMGLIMVFSKISDDLSIYCSDFTYILSDKTILQELKIEGELAAIRKDYLKKKRTNPEVTPFVDQKDVANPFEIYKKIGELAKIDLLKDLENRTLAYLNFSVKIQTEKIADMLNDLLNRVQNQQIIVSELYQYLLIYKGKDDLFDALIFSLKRELKKLSHNFAPKTQPSSISKINLVLVPSLKLEHLPRHNPEIVNICEKLENYVFRGSNKKSSFFSAKNHCGYTKEVNEIVQRILRGDLLTAEAIFHELAKINIESRKDELILLRNDLQSEKVCVRKL
>NZ_LT632617.1|WP_038838484.1|1569801_1571121_-|acetyl-CoA-C-acetyltransferase
MKHQSNLSGRNVYVVDGSRTPFLKAKGVGPFCGSDLAVAAGTTLLNRQPFSPDELDEVIIGSAMPGPDEANIARVVALRLGCGDKVPAFTVMRNCASGMQALDNAAIQIATGRSNLVLAGGTDAMSHAPLLFNEKMASWLANWFAAKSMGQKLALITKFKPSYLAPVIALLRGLTDPIVGLNMGQTAEKVAYRFNITREQMDEFAAQSHLRIAQAYAENRMSEVAPIIDYKGCIYPQDDGIRADSTVEKLSKLKPFFDKKYGMVTPGNSSQITDGACLLLLASAEAVKKYALPVLGRIVDSQWAALDPSQMGLGPVHAATPILERHNLKPQDLDCWEINEAFAAQVLGCLAAWNDEEYCKTQLGLKEAIGAPSLERLNRDGGAIALGHPIGASGARIVLHVLKSLEQKNESRGMAAICIGGGQGGAMYLERVTEVKGHE
>NZ_LT632617.1|WP_038838482.1|1567790_1569809_-|enoyl-CoA-hydratase/isomerase-family-protein
MNNYKHWDLQRDKDAILWLGLNRRDAAVNSINEEVLDELNSLLHEISHDKKAMGLIIYSLKEKGFIAGADVNAFSQFESSSQAVDFLQKGQTVFARLQALSIPSVAMIDGFCMGGGYELALACTYRIATDDKDTRIGLPEVMLGIHPGWGGTVRLPQLIGGFKALSQVILTGSAIPAVKAKSLGMIDEVVPIRQLRRAAVYFIKNKPPRHRASFIESLTNSSLLRKAIAYLLRYNVAKRVRKEHYPAPYAVIDLWEKEGGVGERAYLKEVDSIEKLVSQNDTAKNLIRAFLLRERLKGFAKDSHFKTAHVHVIGAGVMGGDIAAWCALRGLQVTLQDKSYEQIAPAIGRAHKLYSKKLRKPRLIQAAMDRLIADPHGHGVKRADVIIEAVFENLAVKQEIMKTVEKNAKKDAIIATNTSSIPLDEISSVMSKPERLVGIHFFNPVAKMDLVEIVSSSSTTKKVQQSACAFVNQIGKLPLPVKSSPGFLINRVLMPYLMECVQLLDEGYSAETIDEAALQFGMFMGPVELADTVGMDVCLAVAENLTGHFGGTIPQRLRDLVKEGKLGRKTGEGFYKYKNGKVIKKKAPSHVDKTIADRLILRMVNESAACIREKVVEDSDLLDAGMIFATGFAPFRGGPMNYANDFGKDKLETLFKTFESKYGERFKVDTSL
>NZ_LT632617.1|WP_038838480.1|1567005_1567731_-|L,D-transpeptidase-family-protein
MEQKSKSIIRVWYLILLLSQYSFANVYVLPEAGNTIGEIQVAFSEYGETIDEVGRRFNVGYYEMVRANPGVNARYPLTANTKLIIPSRFILPNVPRKGVVINLAEYRLYYFPPDDNVVMTYPVGIGKKGWETPLGLSRIISKEINPTWRPTVKLQKAAESIGAPIPSEFPPGPHNPLGQHVLRLGWPAILIHGSNRVDGIGAKVSAGCIRMLPEDIEHLYSLVSVGTPVRIINAPLQRQAD
>NZ_LT632617.1|WP_038838495.1|1582273_1583527_-|glutamate-5-semialdehyde-dehydrogenase
MNTDIANQLRAAKKATTDLNLIQSDTRTIILKTLAANLEKHIENIIQENQKDLSLMLEQDPRYDRLLLNKERILSLANDVRKVASLPNPLGVNLLEKSMPNGLNIKKITVPLGVIAVIYESRPNVTIDIFSLCFKSGNVCILKGGKEAHFTNSYLLLLIKNTLKNFNINTDIVCLLPPERALMTQLLNATGFVDLCIPRGSQNLINFVRDNAKIPVIETGAGIVHTYFDKSGDLEKGKKIINNAKTRRVSVCNALDTLIIHTDRLKDLPELVKALSKNNVIIYADQEAYQALDKSYPEQLLMKAKPQDFGHEFLDYKLAIKAVPNIQAAIDHVQQFSSHHSEAIIAEEESAIDQFLTEVDAAAVYANASTAFTDGGEFGLGAEIGISTQKVHARGPMGLEALTSYKWVIRGTGQIRN
>NZ_LT632617.1|WP_038838497.1|1583535_1584606_-|glutamate-5-kinase
MKIIIKVGTQSILSVDGSPIYSVLNNLVNQIIYLKNLGHQVILVSSGAVGSGRKIAKNSLGKTYGDTVGEKQLLASIGQPELMNLYSSLFKNENILVSQLLLTKQDFHTRQHYLNIARLLTELLKHQNIIPIVNENDSVAIEELMFTDNDELAGLIAAQINADYLILLTNVDGVFTSHPNDPESKLINTIDPNSGWPNVSAVKSKLGRGGMVSKLDTARKMAGLGINTVIANVNVESIVPKILNREAVGTIILASKRKSSIKRWIAFSHRTSLPSIVINDNLITLLRNGNRVMSILPIGIEDFRGECKRGDLIDILNSNNEKIGVGIARYDFLRLKDYLRLQNKPAFIHYDQLHIL
>NZ_LT632617.1|WP_027265292.1|1584791_1585217_-|GNAT-family-N-acetyltransferase
MNYQLELVVDTKLLEQQDKMIRDGIVNFNAPFTGSKPERYSIYVKDNENNIVGGAIVYAHKSSIYVDALWVSEKYRGRGIGAELLRGVETEAIKRGIPESTLDTFSFQAEGFYLKQGYKHLGIIKNYLEGHDRIYLRKKLK
>NZ_LT632617.1|WP_038838500.1|1585505_1586486_-|hypothetical-protein
MQLKSETKSTFHGKYSKSSPVVGARVKELELIYTHKEIFANYQKVVYDQQKLNVIPLAFKEKADEISKEIYAAYIKKYSDHGLTIENSVDWNNVGFTRTYLSDLENEWNTWFVDPLVATPNDKSHIEGQMYRPAYICALHELMHVEEMTPGISKGQYARFESVVEVLTVTKTIILMDEVYKKTFNLPMDIEVDYENSFKLFGKTIKQGEFANFYRTLEAKYPSLAEALVSKQSLTFLNQTNVEPMNINMQVLGGFLAVVGYAAVALALLLNNASFGTLGLVVTGLGVASIFGGVGLFANGIYKNERTTDNEILDASACLAGNTNSP
>NZ_LT632617.1|WP_038838502.1|1586836_1587784_-|MerR-family-transcriptional-regulator
MTQWFVKDLSQLTGVSVQTLHHYDRIGLLKPSLRLANGYRVYSEKDLLKLQQIIALKFFGFELSQIKTLLAEEGNALNHFNSQARVLEQKASTLLEGAKTLRRIIDSVDKNQSIPWETIIQLIEVYKMTEHLEHGWVKEIFTPDELKQYAEFEKEMKANATPEQKAAMENNWSQLVDEVKNNLKQDPDSKIGIYLGKKIMDWVNGVYGKKYAHLRTKKFEQGFGEGKGLDEVGLTPEIVSWMDKAMDAYWRDRIYGILDQVGKAPSASVLALWNEMLIDMYGEETSRKNAIYEIALNDEEVSPEAKAWLRNVLNS
>NZ_LT632617.1|WP_038838504.1|1588034_1588787_-|MerR-family-transcriptional-regulator
MAYTVKQLAKISNVSVRTLHWYDEIGLLKPAYQGANGYRYYEEKQCLKLQQILFFRELGFPLNDIQKLLMQNDFDHIKALRAHKQVLESDINRKNQLIVTIDKTIQHLKGKHKMSNEELYYGFDSLRQKQYEKELVKEGVVSQDWMDKYKKKINQWTQADKDRFIQEGKDINQALISAINNQLKPTSPEVQAIIHRHHAWVGWNPNKEGYIGLSQRYLTPEFRKFYEQQHPDLLEFIIEGMLFYANKNLD
>NZ_LT632617.1|WP_038838507.1|1588852_1589380_-|GNAT-family-N-acetyltransferase
MTQIEIVIKTQELSDIPVLVDAFQKANWQKPASLFEAYYQEQRKSLRVVWVAYFREQIAGYVTLKWISQYQSFAHQKIPEIMDLNVLPSFRKQGVGTALLQAAEEKAASESDVVGIGVGLYGGHDGGYGQAQRLYVNRGYIPNGLGVTYDYKPTVPGQVYPLDDDFILWFTKKLR
>NZ_LT632617.1|WP_038838510.1|1589376_1590333_-|GNAT-family-N-acetyltransferase
MSVKQEQHLIKVVPYDSSWSMQFEQEAEQIKKALGNNCIDIHHIGSTSVPGLAAKPVIDMIPVVLDISKVDGANAAMRALGYEAKGEYGIPFRRYFQKGDNRRTHHAHIFELGNSEIDRHLKFRDWMRMHPKDREAYARLKQELARRYLDDITTYCLGKEDFIATIDKKAGFNGLRMVKALTTREWDKVRHFRQFYFFDKAGLSDPYTWTFEHNAHVHFVLFQGSEITGYAHLQLWSHNRAALRIIVIDELKRNHQYGTRFLALCEKWLKSQGYQSLHVESSPDALKFYRNNGYIDMPFDDPDGYEGDPRDTAVGKIL
>NZ_LT632617.1|WP_038838512.1|1590336_1592118_-|ABC-transporter-ATP-binding-protein
MTNYLPSHLGSFMWHFLKPYRGIVILFILFALLAGFWGPFNSLLIKSFINTLTEKTSQDLSSLYWIAGLLVLNFIVFDNITWRALGYLNYKYQAIIKSQIISQTFEYVLGGSTQFFQDNLSGRIADQITTLADNLEIILHRVSVDFLRGASLLVVSFITAYFVNVLFFYILFLWFVAFASFSIWMSARLVQLSDDHASSESQLSGQLVDSLANQSNIRIFSRKIYEVERMNTFFRMVQRAFQRKELFIVLLCCAQGGMIAVMMGFASITLIHLYGKGLVSIGDFALILGLSMELGHMMWYTMYQVDQFNQALGKAKQSLNALVIPHEIKDKSNASQLVVTQGQIEFSRVKFHYQGGYSLFQNKSVTIKAGQKVGLVGYSGSGKSTFVNLILRLYEVVEGQILIDGQNLSEVTQESLRQAIAMIPQDPTLFHRSLIENIRYGRTDATDEEVILASRKAHAHEFISLLPEGYKTLVGERGVKLSGGQRQRIAIARAILKNAPILMLDEATSQLDSITESNIQESLWDLMQGKTTLVVAHRLSTLLHMDRILVFDKGHIIEDGTHTELLNRGGLYKTLWNAQVGGFLPDQQNEKGE
>NZ_LT632617.1|WP_038838514.1|1592110_1593571_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MNHKPIQFKDLSLIYPHKTCFQDFSCEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAGEIKIPHDVRFGHLPQVLEDCPDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRSLMRMLEHYPGTLIIASHDTELINTVTDTLWHIDLGQVTVFRGIYFDYQQILEDKKASIEQELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTIRSHTKLGSAITTGNKRLSHINYKKQQLLEELSSLNFPEVIKPKFRLKGLGYHKSLIRIQDASVAYEAVVILEDIHFHLSGCERVALHGDNASGKSTFVKAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVLDLMRSNMPHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGGEKARLSMALIAANPPKLLILDEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQLEVVHHD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

697481 : 759678

Enterobacteria_phage(23.08%)

tRNA,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013101194.1\|697481_698453_+\|transposase	transposase	NA	NA	NA	NA
WP_079996937.1\|698449_698935_+\|transposase	transposase	NA	NA	NA	NA
WP_014326724.1\|699153_702420_+	DEAD/DEAH box helicase family protein	M1GYP4	Paramecium_bursaria_Chlorella_virus	1.6e-36	27.8
WP_010946474.1\|702679_703114_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_010946475.1\|703291_704674_+	replicative DNA helicase	O80281	Escherichia_phage	2.9e-141	58.1
WP_038837770.1\|704675_705749_+	alanine racemase	NA	NA	NA	NA
WP_010946477.1\|705821_706271_+	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_029345979.1\|706576_707011_+	CBS domain-containing protein	NA	NA	NA	NA
WP_011945882.1\|707126_708314_+	membrane protein	NA	NA	NA	NA
WP_011945883.1\|708425_708698_+	CDGSH iron-sulfur domain-containing protein	NA	NA	NA	NA
WP_011945884.1\|708717_710268_+	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.4e-19	35.3
WP_010946482.1\|710419_711409_+	lipoyl synthase	NA	NA	NA	NA
WP_011945886.1\|711720_712002_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_014843552.1\|712402_713911_-	peptide MFS transporter	NA	NA	NA	NA
WP_010946484.1\|713949_714768_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011945887.1\|714954_716310_+	N-acetyl sugar amidotransferase	NA	NA	NA	NA
WP_038837785.1\|716309_717071_+	glycosyl amidation-associated protein WbuZ	NA	NA	NA	NA
WP_038837788.1\|717067_717709_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_011945890.1\|717721_718420_+	acylneuraminate cytidylyltransferase family protein	A0A1B1IVD3	uncultured_Mediterranean_phage	2.0e-05	32.0
WP_016356750.1\|718416_719439_+	N,N'-diacetyllegionaminate synthase	A0A1B1IVE2	uncultured_Mediterranean_phage	3.5e-35	38.1
WP_038837791.1\|719438_720572_+	UDP-N-acetylglucosamine 2-epimerase (hydrolyzing)	NA	NA	NA	NA
WP_038837794.1\|720561_721170_+	acetyltransferase	NA	NA	NA	NA
WP_010946492.1\|721180_722683_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_010946493.1\|722772_723336_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	8.7e-52	57.5
WP_038837795.1\|723336_724221_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.2e-31	33.7
WP_013101182.1\|724231_725260_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.6e-83	48.2
WP_015444736.1\|725313_726798_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_011213310.1\|726952_727828_+	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	2.1e-92	58.0
WP_027265849.1\|727848_728805_+	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_072401767.1\|728788_729790_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_038837803.1\|730313_731189_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_038837807.1\|731543_732437_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_038837815.1\|733484_734513_+	radical SAM protein	NA	NA	NA	NA
WP_100917199.1\|734697_735772_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	7.7e-57	46.5
WP_040148105.1\|736118_737639_-	hypothetical protein	NA	NA	NA	NA
WP_038837832.1\|737893_738613_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_038837834.1\|738625_739711_+	N-acetylneuraminate synthase family protein	NA	NA	NA	NA
WP_038837836.1\|739707_740709_+	aminoglycoside phosphotransferase family protein	NA	NA	NA	NA
WP_038837837.1\|740719_741847_+	hypothetical protein	NA	NA	NA	NA
WP_038837839.1\|742558_744205_+	hypothetical protein	NA	NA	NA	NA
WP_010946509.1\|744170_745022_+	ABC transporter permease	NA	NA	NA	NA
WP_010946510.1\|745018_746443_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	4.2e-10	27.1
WP_038837842.1\|746448_747606_+	hypothetical protein	NA	NA	NA	NA
WP_011214978.1\|747728_748802_+	acyltransferase	NA	NA	NA	NA
WP_011214979.1\|748970_749864_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011214980.1\|749857_750877_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011945910.1\|751088_751796_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011213314.1\|752354_752549_+	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	3.0e-12	70.6
WP_038837844.1\|752674_754657_-	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	4.4e-50	32.1
WP_010946520.1\|754819_755815_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_010946521.1\|755818_756556_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_010946522.1\|756637_757591_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_038837846.1\|757583_758879_+\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_010946524.1\|759141_759678_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

806844 : 813683

Acinetobacter_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027225204.1\|806844_807621_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	2.5e-57	48.2
WP_027225203.1\|807613_808648_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.2e-75	47.6
WP_011945952.1\|808625_809204_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.3e-55	53.2
WP_010946572.1\|809237_809963_-	LPS export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-17	28.3
WP_011215024.1\|809959_810469_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_011945954.1\|810449_811019_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_011945955.1\|811015_811543_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.4e-27	47.7
WP_010946576.1\|811556_812519_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.2e-38	34.1
WP_010946577.1\|812885_813683_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.3e-21	33.8

DBSCAN-SWA_3

1161742 : 1167679

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038838075.1\|1161742_1162816_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.3e-29	27.5
WP_038838076.1\|1162800_1163415_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	4.6e-22	36.2
WP_038838079.1\|1163411_1164620_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.4e-99	48.7
WP_050566912.1\|1164627_1165095_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.6e-22	49.1
WP_010946915.1\|1165220_1166858_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.3
WP_027265741.1\|1166854_1167679_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	3.0e-53	43.9

DBSCAN-SWA_4

2073202 : 2083324

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038838944.1\|2073202_2074891_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	1.0e-15	30.4
WP_027229267.1\|2075022_2076030_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_027229268.1\|2076153_2077479_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	1.1e-47	31.2
WP_011215982.1\|2077497_2078646_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	2.2e-126	58.5
WP_027265068.1\|2078854_2079967_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	2.3e-51	35.4
WP_010947740.1\|2080061_2081201_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.6e-23	26.9
WP_011946925.1\|2081389_2083324_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	1.3e-147	49.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage