CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT821227	Phoenicibacter congonensis strain Marseille-P3241 chromosome contig00001	12 crisprs	WYL	1	2	0	0

1. NZ_LT821227

CRISPR-Cas detection and classification

Crispr_ID: NZ_LT821227_1

• CRISPR_ID: NZ_LT821227_1
• CRISPR_location: 332-523
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NZ_LT821227_1

Consensus_repeat	Method
CATCCAATCCCGAATTCATGTCTGTCACCAATGTAACACGTTTGTCAC	PILER-CR
AATCCCGAATTCATGTCTGTCACCA	CRISPRCasFinder

spacers of NZ_LT821227_1

>1.1|380|31|NZ_LT821227|PILER-CR
TTTTGCGAATTTAGATCAGTCTGATGCGTTT
>1.2|459|34|NZ_LT821227|PILER-CR
CGCTTGAAGACTGTCATCAATGGCAGCACTGGCA
>1.3|362|54|NZ_LT821227|CRISPRCasFinder
ATGTAACACGTTTGTCACTTTTGCGAATTTAGATCAGTCTGATGCGTTTAAACC
>1.4|441|40|NZ_LT821227|CRISPRCasFinder
CCGCTTGAAGACTGTCATCAATGGCAGCACTGGCACATGC

CRISPR arrays and Neighbor proteins around NZ_LT821227_1

CRISPR arrays

The CRISPR arrays of NZ_LT821227_1

>merge|NZ_LT821227|1|332-523|PILER-CR,CRISPRCasFinder
CATCTAATCCCGAATTCATGTCTGTCACCAATGTAACACGTTTGTCACTTTTGCGAATTTAGATCAGTCTGATGCGTTTAAACCAATCCCGAATTCATGTCTGTCACCACCGCTTGAAGACTGTCATCAATGGCAGCACTGGCACATGCAATCTTGAATTCATGTCTGTCACCAATGTAACACGTTTGTCGC

>NZ_LT821227|1|1|332-523|PILER-CR
CATCTAATCCCGAATTCATGTCTGTCACCAATGTAACACGTTTGTCAC	TTTTGCGAATTTAGATCAGTCTGATGCGTTT
AAACCAATCCCGAATTCATGTCTGTCACCACCGCTTGAAGACTGTCAT	CAATGGCAGCACTGGCACATGCAATCTTGAATTC
ATGTCTGTCACCAATGTAACACGTTTGTCGC

>NZ_LT821227|1|1|337-505|CRISPRCasFinder
AATCCCGAATTCATGTCTGTCACCA	ATGTAACACGTTTGTCACTTTTGCGAATTTAGATCAGTCTGATGCGTTTAAACC
AATCCCGAATTCATGTCTGTCACCA	CCGCTTGAAGACTGTCATCAATGGCAGCACTGGCACATGC
AATCTTGAATTCATGTCTGTCACCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079535106.1|5118_6300_-|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|341466
NZ_LT821227.1|WP_079535108.1|7392_8241_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|153251
NZ_LT821227.1|WP_079535109.1|8241_8916_-|(d)CMP-kinase	unknown	unknown	gnl|CDD|234579
NZ_LT821227.1|WP_079535103.1|2131_2794_-|glycerol-3-phosphate-1-O-acyltransferase-PlsY	unknown	unknown	gnl|CDD|376884
NZ_LT821227.1|WP_157887260.1|4906_5047_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535102.1|566_1565_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|234629
NZ_LT821227.1|WP_157887261.1|6479_7403_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	unknown	unknown	gnl|CDD|260116
NZ_LT821227.1|WP_147571462.1|2993_3218_-|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|376884
NZ_LT821227.1|WP_147571575.1|2781_2997_-|glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl|CDD|376884
NZ_LT821227.1|WP_079535105.1|3222_4560_-|ribosome-biogenesis-GTPase-Der	unknown	unknown	gnl|CDD|234628

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079535106.1|5118_6300_-|iron-containing-alcohol-dehydrogenase	gnl|CDD|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
NZ_LT821227.1|WP_079535108.1|7392_8241_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl|CDD|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	4.56616e-29
NZ_LT821227.1|WP_079535109.1|8241_8916_-|(d)CMP-kinase	gnl|CDD|234579	PRK00023, cmk, (d)CMP kinase.	2.20695e-102
NZ_LT821227.1|WP_079535103.1|2131_2794_-|glycerol-3-phosphate-1-O-acyltransferase-PlsY	gnl|CDD|376884	pfam02660, G3P_acyltransf, Glycerol-3-phosphate acyltransferase. This family of enzymes catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate to form lysophosphatidic acid.	4.85984e-49
NZ_LT821227.1|WP_079535102.1|566_1565_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl|CDD|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	6.20979e-146
NZ_LT821227.1|WP_157887261.1|6479_7403_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase	gnl|CDD|260116	cd13944, lytB_ispH, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. The 4-hydroxy-3-methylbut-2-enyl diphosphate (HMBPP) reductase (called lytB or ispH) is the terminal enzyme of the mevalonate-independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, one of the two metabolic routes for isoprenoid biosynthesis. The MEP pathway is essential in many eubacteria, plants, and the malaria parasite. LytB converts HMBPP into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).	3.55277e-104
NZ_LT821227.1|WP_147571462.1|2993_3218_-|glycerol-3-phosphate-acyltransferase	gnl|CDD|376884	pfam02660, G3P_acyltransf, Glycerol-3-phosphate acyltransferase. This family of enzymes catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate to form lysophosphatidic acid.	1.26519e-19
NZ_LT821227.1|WP_147571575.1|2781_2997_-|glycerol-3-phosphate-acyltransferase	gnl|CDD|376884	pfam02660, G3P_acyltransf, Glycerol-3-phosphate acyltransferase. This family of enzymes catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate to form lysophosphatidic acid.	1.5044e-19
NZ_LT821227.1|WP_079535105.1|3222_4560_-|ribosome-biogenesis-GTPase-Der	gnl|CDD|234628	PRK00093, PRK00093, GTP-binding protein Der; Reviewed.	0

Protein sequences

>NZ_LT821227.1|WP_079535102.1|566_1565_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MSKIAVIGAGSWGCALSQLLAKNGNDIMLWALEPEVEKGINISHKNPIYLSSIVLDDRIKATNSFEEALDGAKLCVVVTPSQFLRSTAEGFKAFVDDDLPIVICSKGAEHDTGLLSSEVLADVLGNERRIAVLSGPTHAEEVIKQVYSAATCACSDLELANRIRDVFSSEYFRVYTMTDVYGVELCATFKNVIAIAVGLCYGLGFGDNTAALIITRGVAEMSRMVKSAGGDERTCQGLAGIGDMVVTCMSRHSRNRRFGEDYLSKGKTLDDFKHDTKMIVEGAVAAQNLQTLSKKFNVELPITNMINDIIWNGANVLEQVKVLASRPLKQEF
>NZ_LT821227.1|WP_079535103.1|2131_2794_-|glycerol-3-phosphate-1-O-acyltransferase-PlsY
MQNIAVLLLLSLVSFLLGSIPCGVLISKVFFHKDVRDEGSGNIGFTNSMRSMGKVGGGAVFVGDFLKGMLAAAIGLYVAPIFLTGAQFPLCENPAELTAALATFFATMGHIFCPWLGWKGGKGISTAFGASFISMSVPVACILFGAFLLVVLATKYVSAGSVTAAALYPLAAFVTHWNSPLPALILSVAGLVVIWAHRGNIVRIKNGTERKIGASKKSDN
>NZ_LT821227.1|WP_147571575.1|2781_2997_-|glycerol-3-phosphate-acyltransferase
MAVLLLLSLVSFLLGSIPCGVLISKVFFHKDVRDEGSGNIGFTNSMRSMGKVGGGAVFVGDFLKGLESCRI
>NZ_LT821227.1|WP_147571462.1|2993_3218_-|glycerol-3-phosphate-acyltransferase
MQNIAVLLLLSLVSFLLGSIPCGVLISKVFFHKDVRDKGSGNIGFTNSMRSMGKVGGGAVFVGDFLKGLESCRI
>NZ_LT821227.1|WP_079535105.1|3222_4560_-|ribosome-biogenesis-GTPase-Der
MKNLKVAIVGRPNVGKSALVNRLCERDEAIVHERRGVTRDRTYHPCEWNGVAFDLIDTGGLEMSDDDCFKGDIRSSALMGAEEADSIVFLVDGKVGIQSDDQDVACLLKKTKKQVHLAVNKMDNPDDEGEIWNFMSLGFGQPIAVSAVHGHGTGDLLDIVVDDLKRVAEQDQDEADSFIGEEDDFINVAIIGRPNAGKSTLTNKLTDQNRSIVSDVAGTTRDAIDTVVEHEGRTYRIIDTAGLRRKSKIDDNVEYFSYVRAMRAIDRADVAVLVVDGTLGITNEDQRVANYAEEKHCAMCIALNKWDAVEGAEAKKEIRADLEEFMQFASYAPIQSISALTGKKVDKIWDSINIAYDNYCKKLSTAKLNEWLADIRSSGHTITSGKAILRMKYITQSGVKPPTFQIFCNRPDIVTPNYKRFLENKLRDSFDLSGTPIKIFMRGKD
>NZ_LT821227.1|WP_157887260.1|4906_5047_-|hypothetical-protein
MPAFAGCDDVLVIILELLVGFYGEPSMRLADEILAFVPIFAIISWL
>NZ_LT821227.1|WP_079535106.1|5118_6300_-|iron-containing-alcohol-dehydrogenase
MTAFNDFEFYSPTRFIFGKDAELKVGERLKEAGAKRALIHFGSHHAKESGLIDKVEKSLEDAGVEWVDLGGVRPNPEISLVREGQKLCKEHDIDYLIAVGGGSVIDSIKCIADSAHYDGDPWDFVCKKIPVTEALPIAVVLTIPAAGSESSKNSVISNDELGLKTGFGSDINRPKFAFLNPELTMSLPAYQTAAGCTDMFAHLLERFFDDAENIPATDNLNMSLMKTIRANALRVLEEPDNYDARANIMWAGALCHNGIAGCGRHEDWATHGMEHELSALKPDVTHGAGLAVLFPAWMDYVYKENPARFALYGREVFGITTTDDIEADARAAIRATREFFVSMNMPTRLSEFGFVEDDIEKMLPTLKENKGELFGSFKKLTMGDAVNIYKSAL
>NZ_LT821227.1|WP_157887261.1|6479_7403_-|4-hydroxy-3-methylbut-2-enyl-diphosphate-reductase
MGARVKVVCANPAGACYGVVRALELTSKAIDSEQNVSTFGEIIHNPIVVNDFSSRGVSVIKSPAEACGTVVLRSHGVKPSVEREIEKHAKVIDATCPYVKKAQLSAKNLGERHELVIVVGEEGHPEVEAIVEYAKQGATKVVLVPDVDNLPDSYPHSVGIVSQTTQSEETFSKIVREVKKRMNRGQKQPFSPEGSQNLEIKNTICNATKERQEAALDLSAKANVMIVLGGKKSANTRRLFELCQEKCKHCFHIESMVELDALVDYIRKILCENFDSEFLIGITAGASTPASQIDELESFLDKNFVAS
>NZ_LT821227.1|WP_079535108.1|7392_8241_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MKILRTEEMFDLPFDGEFNVDKEGIPIKRRITHWFSWFAFFVLGFIAKVAFRYKVINKRKVTDFKDKRGCIIIANHESYLDAVFAFLGPRPKCCPRIVARETLFEGKPWIARQIIARAGAFPISRETSDRKSLKRAVKMLQRKEMVTIMPEGTRRGRGTADLSLHSGFAFIAKMAGDAPIIPCAFRNVGKIKKKGERLHFPKVEIEYGDPILLSDFDCFEKKDRLAICSWWAMREVFALRDAIKPEQVDMKTLFPNDIDYSDVEEVKNLHIHHTTEELLGGC
>NZ_LT821227.1|WP_079535109.1|8241_8916_-|(d)CMP-kinase
MIVAIDGPCGAGKSSVAKVVARELGFSCLDTGAMYRAVAWLAKHNGVDLDDNEALGKVARECEIAFGHTNEDPTPNQVFVDGHDVTSDIRTAEIDKAVSPVSSAPAVREALVLQQQRIGNAGDYVVEGRDIGTVVFPNAEVKVFLTASPEERAHRRVRQNADRCVGSIDYEEVLADIIRRDRADTTRDTSPLKKADDAVEIDSTGDHIETVIAKICELANERRR

Crispr_ID: NZ_LT821227_2

• CRISPR_ID: NZ_LT821227_2
• CRISPR_location: 440940-441030
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_2

Consensus_repeat	Method
CGCAATGTGGCTCTTGATTTGAGGGTT	CRISPRCasFinder

spacers of NZ_LT821227_2

>2.1|440967|37|NZ_LT821227|CRISPRCasFinder
TTAACAGGCACAAACAGCACGCCTTGCCCTTCCTCAG

CRISPR arrays and Neighbor proteins around NZ_LT821227_2

CRISPR arrays

The CRISPR arrays of NZ_LT821227_2

>merge|NZ_LT821227|2|440940-441030|CRISPRCasFinder
CGCAATGTGGCTCTTGATTTGAGGGTTTTAACAGGCACAAACAGCACGCCTTGCCCTTCCTCAGCGCAATGTGACTCTTGATTTGAGGGTT

>NZ_LT821227|2|2|440940-441030|CRISPRCasFinder
CGCAATGTGGCTCTTGATTTGAGGGTT	TTAACAGGCACAAACAGCACGCCTTGCCCTTCCTCAG
CGCAATGTGACTCTTGATTTGAGGGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079535436.1|436720_437488_+|tryptophan-synthase-subunit-alpha	unknown	unknown	gnl|CDD|237285
NZ_LT821227.1|WP_079536852.1|440316_440865_+|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|223707
NZ_LT821227.1|WP_079535443.1|443819_444488_-|hydrogenase-nickel-incorporation-protein-HypB	unknown	unknown	gnl|CDD|349775
NZ_LT821227.1|WP_079535432.1|432860_433877_+|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234682
NZ_LT821227.1|WP_079535439.1|441188_441866_-|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NZ_LT821227.1|WP_079535447.1|448744_449341_+|DUF1643-domain-containing-protein	unknown	unknown	gnl|CDD|377919
NZ_LT821227.1|WP_079535444.1|444636_447624_+|DEAD/DEAH-box-helicase	unknown	unknown	gnl|CDD|223989
NZ_LT821227.1|WP_079535448.1|449491_450190_-|NAD(P)H-hydrate-epimerase	unknown	unknown	gnl|CDD|223140
NZ_LT821227.1|WP_079535431.1|432291_432858_+|aminodeoxychorismate/anthranilate-synthase-component-II	unknown	unknown	gnl|CDD|235552
NZ_LT821227.1|WP_079535437.1|437707_438205_+|prolyl-tRNA-editing-protein	unknown	unknown	gnl|CDD|239827
NZ_LT821227.1|WP_079535445.1|447620_448019_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl|CDD|239517
NZ_LT821227.1|WP_079535434.1|434779_435538_+|phosphoribosylanthranilate-isomerase	unknown	unknown	gnl|CDD|238237
NZ_LT821227.1|WP_079535435.1|435537_436728_+|tryptophan-synthase-subunit-beta	unknown	unknown	gnl|CDD|235288
NZ_LT821227.1|WP_079535442.1|443025_443496_+|hypothetical-protein	unknown	unknown	gnl|CDD|180850
NZ_LT821227.1|WP_079535440.1|441948_442662_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|319872
NZ_LT821227.1|WP_079535438.1|438413_439784_+|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NZ_LT821227.1|WP_079535446.1|448183_448735_+|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|180928
NZ_LT821227.1|WP_079535441.1|442729_443014_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535430.1|430827_432291_+|anthranilate-synthase-component-I-family-protein	unknown	unknown	gnl|CDD|223225
NZ_LT821227.1|WP_079535433.1|433892_434780_+|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl|CDD|234710

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079535436.1|436720_437488_+|tryptophan-synthase-subunit-alpha	gnl|CDD|237285	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional.	5.84321e-117
NZ_LT821227.1|WP_079536852.1|440316_440865_+|hypoxanthine-phosphoribosyltransferase	gnl|CDD|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	6.70687e-75
NZ_LT821227.1|WP_079535443.1|443819_444488_-|hydrogenase-nickel-incorporation-protein-HypB	gnl|CDD|349775	cd05390, HypB, nickel incorporation protein HypB. HypB is one of numerous accessory proteins required for the maturation of nickel-dependent hydrogenases, like carbon monoxide dehydrogenase or urease. HypB is a GTP-binding protein and has GTP hyrolase activity. It forms homodimer and is capable of binding two nickel ions and two zinc ions. The active site is located on the dimer interface. Energy from hydrolysis of GTP is used to insert nickels into hydrogenases.	1.90113e-107
NZ_LT821227.1|WP_079535432.1|432860_433877_+|anthranilate-phosphoribosyltransferase	gnl|CDD|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	0
NZ_LT821227.1|WP_079535439.1|441188_441866_-|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.51905e-20
NZ_LT821227.1|WP_079535447.1|448744_449341_+|DUF1643-domain-containing-protein	gnl|CDD|377919	pfam07799, DUF1643, Protein of unknown function (DUF1643). The members of this family are all sequences found within hypothetical proteins expressed by various bacterial species. The region concerned is approximately 150 residues long.	5.84166e-38
NZ_LT821227.1|WP_079535444.1|444636_447624_+|DEAD/DEAH-box-helicase	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	1.74619e-79
NZ_LT821227.1|WP_079535431.1|432291_432858_+|aminodeoxychorismate/anthranilate-synthase-component-II	gnl|CDD|235552	PRK05670, PRK05670, anthranilate synthase component II; Provisional.	3.61017e-98
NZ_LT821227.1|WP_079535437.1|437707_438205_+|prolyl-tRNA-editing-protein	gnl|CDD|239827	cd04335, PrdX_deacylase, This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.	1.36302e-47
NZ_LT821227.1|WP_079535445.1|447620_448019_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase	gnl|CDD|239517	cd03425, MutT_pyrophosphohydrolase, The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic pyrophosphate (PPi). This enzyme requires two divalent cations for activity; one coordinates the phosphoryl groups of the NTP/dNTP substrate, and the other coordinates to the enzyme. It also contains the Nudix motif, a highly conserved 23-residue block (GX5EX7REUXEEXGU, where U = I, L or V), that functions as metal binding and catalytic site. MutT pyrophosphohydrolase is important in preventing errors in DNA replication by hydrolyzing mutagenic nucleotides such as 8-oxo-dGTP (a product of oxidative damage), which can mispair with template adenine during DNA replication, to guanine nucleotides.	9.94588e-47
NZ_LT821227.1|WP_079535434.1|434779_435538_+|phosphoribosylanthranilate-isomerase	gnl|CDD|238237	cd00405, PRAI, Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, monofunctional and thermolabile, but in some thermophile organisms PRAI is dimeric for reasons of stability and in others it is fused to other components of the tryptophan biosynthesis pathway to form multifunctional enzymes.	2.20987e-66
NZ_LT821227.1|WP_079535435.1|435537_436728_+|tryptophan-synthase-subunit-beta	gnl|CDD|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
NZ_LT821227.1|WP_079535442.1|443025_443496_+|hypothetical-protein	gnl|CDD|180850	PRK07116, PRK07116, flavodoxin; Provisional.	5.46783e-19
NZ_LT821227.1|WP_079535440.1|441948_442662_+|4Fe-4S-binding-protein	gnl|CDD|319872	cd10550, DMSOR_beta_like, uncharacterized subfamily of DMSO Reductase beta subunit family. This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	1.07997e-13
NZ_LT821227.1|WP_079535438.1|438413_439784_+|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	9.17103e-141
NZ_LT821227.1|WP_079535446.1|448183_448735_+|adenine-phosphoribosyltransferase	gnl|CDD|180928	PRK07322, PRK07322, adenine phosphoribosyltransferase; Provisional.	3.52204e-68
NZ_LT821227.1|WP_079535448.1|449491_450190_-|NAD(P)H-hydrate-epimerase	gnl|CDD|223140	COG0062, COG0062, Uncharacterized conserved protein [Function unknown].	2.8807e-34
NZ_LT821227.1|WP_079535430.1|430827_432291_+|anthranilate-synthase-component-I-family-protein	gnl|CDD|223225	COG0147, TrpE, Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism].	2.65945e-172
NZ_LT821227.1|WP_079535433.1|433892_434780_+|indole-3-glycerol-phosphate-synthase-TrpC	gnl|CDD|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	1.25818e-125

Protein sequences

>NZ_LT821227.1|WP_079536852.1|440316_440865_+|hypoxanthine-phosphoribosyltransferase
MRDDLTEVVYTEKKIAARVEELGFQITDDFKDKVKDGIVAITVLRGAITFSTDLCRCIDLPMEADFMQLSSYGDGHKSSGSVKIKKDVSSSITGKHVLVIEDIYDTGNSMQFLTNFLQSKNPKSISTAVLLRKDVENQIPFDIDYLAFHCPNEFIVGYGLDYAQKYRNLPYIGILKPEIYLS
>NZ_LT821227.1|WP_079535438.1|438413_439784_+|NCS2-family-permease
MEVERVAKFFELQKHGTNVKTEVLAGCVTFLSMAYILAVNPSILSSSGMDAAGVFTATAVSAAFATLIMAFYANYPVALASGMGLNAYFVYSVCVPMAQAGIQDPWQIALTAVLCEGIIFIMLTLCKFREALINDVPANLKYGISAGIGLFIAIVGLKGAGIVVPDESTIVALGNFASPEVVLALVGLIVCALMYHYKVPGYILWAILVTWGLGMVAQTAGWYVVDPEAGVYSLFPDFSKGISIAAPAFCAFNFDYVAGHIIEFIVIVFAFLFVDLFDTAGTLIAVAGKADLLDEDGNLPKAKQALMADAIGTVAGACLGTSTVTSYVESSAGVAAGGRTGLTAFTTAILFIVALVLSPIFLAIPSFATTPALVFVGLLMVSNVRNMDFSEDIAGAMGGYLALIMMPFTYSIANGIMFGMLAFVIIRIFQGKANKVHWVLWVASIIFVLRIISLIA
>NZ_LT821227.1|WP_079535437.1|437707_438205_+|prolyl-tRNA-editing-protein
MHKQDVYDFLNDNNVDYEAIEHGAVWTMDELCDVELPHKEADAKNLFIRDDKKNNYYLISVRGNKHLDIKAFRKLHETRPLKFCQEEELKDKLDIYAGAVSPFGIMNNVDKDVTFFIDEDFFADEGLIGCHPNDNTATVFLKAEDLVKLLQAHGNNVVKTQIPEK
>NZ_LT821227.1|WP_079535436.1|436720_437488_+|tryptophan-synthase-subunit-alpha
MNRIKTAFENGKAFIPFITCGDPDLQTTAAAVREMATNGADLIELGIPFSDPTAEGPVIQGANFRALRGGVTTDKVFDLVRDLRKDVSVPFVFMTYANVVFSYGAEKFISTCSEIGVDGIILPDVPFEEKEEFAGICKANDVALISMVAPTSEDRIAMIAKEAEGFLYVVSSLGVTGMRSEIKTDLPSIIKVVRANSQIPCAIGFGISTPQHAHDMAKISDGAIVGSAIIKILAEHGKEAPARIGDYVRGMKEAL
>NZ_LT821227.1|WP_079535435.1|435537_436728_+|tryptophan-synthase-subunit-beta
MTNENGRFGIHGGQYIPETLMNAVIELEEAYNFYKNDPDFNRELQELLEEYGGRPSRLYYAKKMTEDLGGAKIYLKREDLNHTGAHKINNVLGQALLAKKMGKTRLIAETGAGQHGVATATAAALMGMECVVFMGEEDIVRQKLNVYKMRLLGADVVSVKSGTATLKDAVSEAMREWTNRISDTHYCLGSVMGPHPFPTIVRDFQAVISKEVKEQMLEKEGRLPDAVIACVGGGSNAIGSFYNFIEDEEVALIGCEAAGRGIDTFETAATISTGSLGIFHGMKSYFCQDKYGQIAPVYSISAGLDYPGVGPEHAWLNDIGRAQYVAVTNDEAVNAFEYLSKMEGIIPAIESAHAVAHAMKIAPDMDKDKIVVITISGRGDKDCASIARYKGEDIDE
>NZ_LT821227.1|WP_079535434.1|434779_435538_+|phosphoribosylanthranilate-isomerase
MTKIKFCGMMCEADIKAANEIKPDFVGFVFAPKSKRCVSQSSAEKLKCLLNPSIKAVGVFVDAPVADVAQLVRNNVIDVIQLHGSENECFVEELKNELDGLSSGSLLNQSRNNHLGQVPIIKACRANSAQDIKETIEFPCDYLLFDNGPGGTGKKFDWVRLKETMRPSNFEDPLESKTSRCKLQKLANNGCDFRNPFRPYFLAGGLDAQNVAKAISELHPYAVDVSSGIETEGTKDIQKMKAFAAAVRKDEK
>NZ_LT821227.1|WP_079535433.1|433892_434780_+|indole-3-glycerol-phosphate-synthase-TrpC
MTILDEIATFAKQRVSFAQMTISAEDIKARALELPRGNFDFETALKSGDIAFICECKKASPSKGLIASDFPYLQIAKEYERAGANAISVLTEPKWFLGSDDYLAEVASAVNIPCLRKDFTVDDYMIYEAKLLGASAVLLICSILSKQQIADYIELCDALGMSALVEAHDDEEVRVALEAGARIIGVNNRNLKDFTVDTENSKRLRELVPTDVLFVAESGIKTAEDVAAMRNVGADAVLVGETLMTAEDKSAKLLELRGKEIPCFSNSNLNAVSPSYYDDSSTQNLTSMDESEVGF
>NZ_LT821227.1|WP_079535432.1|432860_433877_+|anthranilate-phosphoribosyltransferase
MIKEAIIKIVNKKDLSYDEAYAVMNEIMSGDTSQVQNAAFLSALSTKSARAETTDEIAGCAAAMRDHATQVDTGMDIFEIVGTGGDNAQSFNISTTSALVCAAGGMKVAKHGNRAASSKCGTSDCLEALGVNIDQSPEKCIELLNEVGMCFFFAQKYHASMKYVGPIRKELGFRTVFNILGPLTNPASPTMQLLGVYDEYLVEPLAQVLISLGVKRGMVVFGKDKLDEISLSSPTKICEFKDGWFKSYTITPEEFGFSTCEKSELVGGEPEENASITRAILAGDKGPKRDAVLMNAGASLYIAGKANSMKEGIALAADLIDSGKAAVTLGKLIQVSNR
>NZ_LT821227.1|WP_079535431.1|432291_432858_+|aminodeoxychorismate/anthranilate-synthase-component-II
MTLLIDNYDSFSYNLYQMVGMIDPDIRVVKNDELTVEEIKSLNPKRIILSPGPGRPEDAGITIDVVPLGREIPLLGVCLGHQAICSAYGANVIHAKELMHGKQSTVKFDLSCPLFKGISDEEKVGRYHSLAVDAKTLPCDLMPVAFAEDGEIMAVQHKEFPIFGVQFHPESILTPCGFEILKNFIREI
>NZ_LT821227.1|WP_079535430.1|430827_432291_+|anthranilate-synthase-component-I-family-protein
MKFSPSLAEVKSIADTDNFSIAPISCEILSDICTPIEAMQILKGVSTHCYMLESALANETWGRYTFLGFDPKMEITCVNGEMRAGDISIKTDNPSTVLREILSRYKSPKIEGLPTFTGGLVGYFSYDYLGYSEPKAKTSADDTENFKDVDLMLFDRVIAFDNVRQKIILIANVHLDNVEVEYNKAVLELKRMADLLRSGKKTDDVPGCLTGDVTPLFNKQQYCDMVETARHHIFEGDIFQIVLSNRLSAPFEGSLLGTYRMLRTINPSPYMFYFSGTDVEIAGASPETLVKLEDGVLHTFPLAGTRPRGKTRIEDDLLEMELLLDKKELAEHNMLVDLGRNDLGKVSKFGTVEVEIFHTVEKYSHVMHIGSTVRGEICDDCDALDAIEAVLPAGTLSGAPKTRACQLINELENNKRGVYGGAIGYIDFTGNMDTCIAIRIAYKKNGQVFVRSGAGIVADSVPEKEYQECINKAQAVVNALKAAEEEL
>NZ_LT821227.1|WP_079535439.1|441188_441866_-|Crp/Fnr-family-transcriptional-regulator
MKNYYAVIKSSSLFSGISENELTVVLPCLGTSIKKYEKGDFMLRAGDSTDSIGLVLMGSTLVIQEDIWGNRNILHKVNPGQTFAAAFACAPGSVLNVSVIAENPATVMFLSVKKILTTCPSGCAHHNRIIRNLLAEIAEKSLQLNEKLTHIGQRTTRAKLMAYLSDEMKRKNKCEFDIPFSRQQLADYLGVERSGLSLELGKMKNEGMLDYHKNHFKLKPWQELD
>NZ_LT821227.1|WP_079535440.1|441948_442662_+|4Fe-4S-binding-protein
MKRRIIEIDEEKCNGCGACAEVCHEGAIAMIDGKAKLIRDDYCDGLGDCLPACPTGAITFVEREAAPYDEKAVIANMEAKMQKEGMTLPCGCPGSQSRKIKHASSVPEPARHAEAASQLSQWPIQIKLVPVNAPYFDDAKLLIAADCTAYAHASFHERFIKGHITLVGCPKLDAVDYSEKLTEIIGNNDIKSVTIVRMEVPCCAGLEIATKKALQRSGKFIPWHVVTVTVDGKLIES
>NZ_LT821227.1|WP_079535441.1|442729_443014_+|hypothetical-protein
MQRWSLNVATLAVEFNPFIVLPSLLLIKGGVLFLHEFVYLCLKGFSIFTSSNIRLSMMHNLCELRGPDASVATFMWEQQAREQSLLNVFALEKS
>NZ_LT821227.1|WP_079535442.1|443025_443496_+|hypothetical-protein
MKKAVIYFSYEGNTLEAAEKIAKETGADLIQIETVEKLPEDRNVMLKKGAFQAMSGAKPAIKDLPALDSYDELILGSPVWAGVVASPVNTFLKNCNCLDKITAVFTLSGSGRNERCIKKLSKILPNLEHQVSLFDRKSEGSNKNPELVADFVSKIS
>NZ_LT821227.1|WP_079535443.1|443819_444488_-|hydrogenase-nickel-incorporation-protein-HypB
MGDVKIIELKASIFENNDKRAQLLREELKGKGTYLLNVMSSPGSGKTTTLVNTINRIKDKLKIAVMQADIDSDKDARTVASETGVESIQLHTGGMCHLDADMTRQGIESLDGDFDLVILENVGNLVCPAEFDTGAVKSITILSVPEGDDKPLKYPLMYQVSSLALINKIDVLPYFDFDVDKAKEYIARRNPDAKVLPVSGRTGEGIEEFAQWLLDEVAAWKA
>NZ_LT821227.1|WP_079535444.1|444636_447624_+|DEAD/DEAH-box-helicase
MTVSNELIIEEIRVKSDFDQYGDKHFYSAIDFSKSLESSFIGSCFEPDERYAPHIVSNDSDKKDDVLSVIKREINDCVSFDFSVAFITDSGIQVLAQVFSELKKRGIPGRILTSTYQMFNTPDALRKLLEYPNIESRIFNGDLHSKGYFFDRREISTIIIGSSNLTQAALTCNKEWNVLFKSFPGGKILEESKKEFKKLWASPEAIKLTSSWIDSYEEAFLELKSFRSSSLDAQRKAQKEISGISENKRAISKQNKDSDPFLGCSIKPNKMQSQALEALEVLHSRNASRALLISATGTGKTYLSALDVFLTKPKKVLFVAHRARILRDSMNSFKNVLEDRYSYGMYGGSNKEKSSSCVFAMVGTLQSHLMDFKPDEFDCIIVDEAHRVGAAGYQKIIEYFTPKFLLGMTATPNRTDGYDVYQLFNHVIAYRITLQDALDNDMLTPFHYFGIADLEIDENNVEDVSLFRKLTSKERVRHITEKIEEYSVRKESRKGLIFCSRNDEAKTLSAEFNKLGYKTRAISGETSNAERNQAILDLEKGNLQYIFSVDIFNEGIDIPSLNQIIMLRKTESAIIFVQQLGRGLRKADDKEYTLVLDFIGNYQQNYLIPVALSGDRTYNKDNLRKVVKEGSSSIPGSSTVTFDEIAERRIFRAIEVSSFSNAQLIRREYEDLKRQLGRIPTLLDFDEQGAIDPLLIISKYKSYTDFLQRYDADCRSKCNEVQLSFLRFVSKRFAPGNRELELKIINNLAIRNLAFSDFSNSFEGTKDELDSAVNALSGHYFRNSPQIMGNDKLLSAEFRESFDDVYFCQYLKDIIAFGLARNKRQYSKRYKDTDFVLYEKYTSSEVCYLCKWAKEPNYQNVGGYFFDEKTNTFPVFINYEKDPSISVTTQYEDRFISDRKIVAISKSKRNLNSPEICMLKDAYSNGMRCFLFLRKNKEDRDANKEYYFLGEIHPTGVFKQILMADNKTNAVEIEYELENPVRADLYDYFLSNFGD
>NZ_LT821227.1|WP_079535445.1|447620_448019_-|(deoxy)nucleoside-triphosphate-pyrophosphohydrolase
MKTINVVAAVIVKNGTILATQRGYGEFEGGWEFPGGKIESGEKPKDAIIREIHEELGATIEVDEFLCQVEYDYPTFHLSMKTFLCKLCDPHFKLLEHHAAKWLTPTHLNEVDWLPADVQIVDLIREKGICGN
>NZ_LT821227.1|WP_079535446.1|448183_448735_+|adenine-phosphoribosyltransferase
MEYTIDIAGLKRDLTLFPVSEDTMIGALILFGDVELTTYCAAELLKRAPEFDIILTAEAKSIPLAYEMARESGMNDYVVARKSQKVYMGDIVQAKLQSITTKGEQKLYLGKSDFKKLANRRVLIVDDVVSTGESLRALENLADAAHANIVGKMAILEEGDSQNRADVITLGELPLFDHNGQPK
>NZ_LT821227.1|WP_079535447.1|448744_449341_+|DUF1643-domain-containing-protein
MRHVPKSTTKECDCLSFDEALAQALVENVEYDVEKWLYVPNTYCEYRYVLGTRGANPLIVVGVNPSTAAPDALDPTLQSAERIAHSNGYDSFLMLNVYPQRATDPNDMEKNRNSFLEKENVEAFKYLLSLSPSKDVWCAWGNVVSKRGYLRDCVNDLVAAGDEAGANWLCSGEPLKSGNPHHPLYLKASTRLQPFFPN
>NZ_LT821227.1|WP_079535448.1|449491_450190_-|NAD(P)H-hydrate-epimerase
MEPILTVQQMRELDEFVINRDDAAQSLMRKAGEALAEELLPFKSIAIVCGSGNNGGDGYAATYALQEKHQLDGKFITIFYTKEPKSPESIFFFEGINSEDIKLEQFSTDEGVKNILAESDCIVDCLLGTGFSGVPRGDIKDAIEIVNEVKLAHPEITVLSMDINSGVNGDTGEGVIGVNSDITLSIGYKKRGMITSEFSKWSKKVVNKNIGYELSKDNFKPFDSPDDILWVE

Crispr_ID: NZ_LT821227_3

• CRISPR_ID: NZ_LT821227_3
• CRISPR_location: 584189-584342
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_3

Consensus_repeat	Method
TTTTTCTTCTTGCGCAATTAAACAATCAAGGAAGACTCAGTGATAAGTG	CRISPRCasFinder

spacers of NZ_LT821227_3

>3.1|584238|56|NZ_LT821227|CRISPRCasFinder
CTCTAAATAGTGCCTGCCGTAATAGGTGCCAGCCATAATTCTTTCAATTTAGCTGT

CRISPR arrays and Neighbor proteins around NZ_LT821227_3

CRISPR arrays

The CRISPR arrays of NZ_LT821227_3

>merge|NZ_LT821227|3|584189-584342|CRISPRCasFinder
TTTTTCTTCTTGCGCAATTAAACAATCAAGGAAGACTCAGTGATAAGTGCTCTAAATAGTGCCTGCCGTAATAGGTGCCAGCCATAATTCTTTCAATTTAGCTGTTTTTTCTTCTTGCGCAATTAAACAATCAAGGCAGACTCAGTGATAAGTG

>NZ_LT821227|3|3|584189-584342|CRISPRCasFinder
TTTTTCTTCTTGCGCAATTAAACAATCAAGGAAGACTCAGTGATAAGTG	CTCTAAATAGTGCCTGCCGTAATAGGTGCCAGCCATAATTCTTTCAATTTAGCTGT
TTTTTCTTCTTGCGCAATTAAACAATCAAGGCAGACTCAGTGATAAGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079535617.1|573396_574092_+|dTMP-kinase	unknown	unknown	gnl|CDD|234814
NZ_LT821227.1|WP_079535631.1|590591_591548_+|carbamate-kinase	unknown	unknown	gnl|CDD|237071
NZ_LT821227.1|WP_079535627.1|586405_586648_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535618.1|574115_575240_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|273213
NZ_LT821227.1|WP_079535626.1|584504_586217_-|amidohydrolase	unknown	unknown	gnl|CDD|238625
NZ_LT821227.1|WP_079535628.1|586698_587655_+|acetylglutamate-kinase	unknown	unknown	gnl|CDD|239783
NZ_LT821227.1|WP_079535625.1|582866_583985_+|hypothetical-protein	unknown	unknown	gnl|CDD|350345
NZ_LT821227.1|WP_079535622.1|579539_580466_+|DegV-family-protein	unknown	unknown	gnl|CDD|273257
NZ_LT821227.1|WP_079535632.1|591629_592775_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|224747
NZ_LT821227.1|WP_079535634.1|595057_595414_+|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079535623.1|580584_581262_+|orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234771
NZ_LT821227.1|WP_079535635.1|595444_595828_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_147571517.1|581823_582069_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535630.1|589575_590571_+|ornithine-carbamoyltransferase	unknown	unknown	gnl|CDD|179366
NZ_LT821227.1|WP_079535616.1|570871_573382_+|DNA-topoisomerase-I	unknown	unknown	gnl|CDD|235971
NZ_LT821227.1|WP_079535621.1|578020_578923_+|DegV-family-protein	unknown	unknown	gnl|CDD|273257
NZ_LT821227.1|WP_079535629.1|588099_589314_+|arginine-deiminase	unknown	unknown	gnl|CDD|234949
NZ_LT821227.1|WP_079535633.1|593277_594621_+|MFS-transporter	unknown	unknown	gnl|CDD|340924
NZ_LT821227.1|WP_079535620.1|576570_578004_+|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|236426
NZ_LT821227.1|WP_079535619.1|575236_576247_+|hypothetical-protein	unknown	unknown	gnl|CDD|224688

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079535617.1|573396_574092_+|dTMP-kinase	gnl|CDD|234814	PRK00698, tmk, thymidylate kinase; Validated.	4.97488e-75
NZ_LT821227.1|WP_079535629.1|588099_589314_+|arginine-deiminase	gnl|CDD|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_LT821227.1|WP_079535618.1|574115_575240_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|273213	TIGR00678, DNA_polymerase_III_subunit_delta', DNA polymerase III, delta' subunit. This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair].	5.89969e-44
NZ_LT821227.1|WP_079535626.1|584504_586217_-|amidohydrolase	gnl|CDD|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	2.48563e-106
NZ_LT821227.1|WP_079535628.1|586698_587655_+|acetylglutamate-kinase	gnl|CDD|239783	cd04250, AAK_NAGK-C, AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the non-acetylated, cyclic route of ornithine biosynthesis. In this pathway, glutamate is first N-acetylated and then phosphorylated by NAGK to give phosphoryl NAG, which is converted to NAG-ornithine. There are two variants of this pathway. In one, typified by the pathway in Thermotoga maritima and Pseudomonas aeruginosa, the acetyl group is recycled by reversible transacetylation from acetylornithine to glutamate. The phosphorylation of NAG by NAGK is feedback inhibited by arginine. In photosynthetic organisms, NAGK is the target of the nitrogen-signaling protein PII. Hexameric formation of NAGK domains appears to be essential to both arginine inhibition and NAGK-PII complex formation. NAGK-C are members of the Amino Acid Kinase Superfamily (AAK).	1.21251e-106
NZ_LT821227.1|WP_079535625.1|582866_583985_+|hypothetical-protein	gnl|CDD|350345	cd14495, PTPLP-like, Protein tyrosine phosphatase-like domains of phytases and similar domains. This subfamily contains the tandem protein tyrosine phosphatase (PTP)-like domains of protein tyrosine phosphatase-like phytases (PTPLPs) and similar domains including the PTP domain of Pseudomonas syringae tyrosine-protein phosphatase hopPtoD2. PTPLPs, also known as cysteine phytases, are one of four known classes of phytases, enzymes that degrade phytate (inositol hexakisphosphate [InsP(6)]) to less-phosphorylated myo-inositol derivatives. Phytate is the most abundant cellular inositol phosphate and plays important roles in a broad scope of cellular processes, including DNA repair, RNA processing and export, development, apoptosis, and pathogenicity. PTPLPs adopt a PTP fold, including the active-site signature sequence (CX5R(S/T)) and utilize a classical PTP reaction mechanism. However, these enzymes display no catalytic activity against classical PTP substrates due to several unique structural features that confer specificity for myo-inositol polyphosphates.	3.20943e-108
NZ_LT821227.1|WP_079535622.1|579539_580466_+|DegV-family-protein	gnl|CDD|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	2.16888e-75
NZ_LT821227.1|WP_079535632.1|591629_592775_+|serine/threonine-protein-kinase	gnl|CDD|224747	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism].	5.59257e-14
NZ_LT821227.1|WP_079535634.1|595057_595414_+|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	0.0014459
NZ_LT821227.1|WP_079535623.1|580584_581262_+|orotate-phosphoribosyltransferase	gnl|CDD|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	7.80467e-62
NZ_LT821227.1|WP_079535631.1|590591_591548_+|carbamate-kinase	gnl|CDD|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_LT821227.1|WP_079535630.1|589575_590571_+|ornithine-carbamoyltransferase	gnl|CDD|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NZ_LT821227.1|WP_079535616.1|570871_573382_+|DNA-topoisomerase-I	gnl|CDD|235971	PRK07219, PRK07219, DNA topoisomerase I; Validated.	0
NZ_LT821227.1|WP_079535621.1|578020_578923_+|DegV-family-protein	gnl|CDD|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	1.71029e-66
NZ_LT821227.1|WP_079535633.1|593277_594621_+|MFS-transporter	gnl|CDD|340924	cd17366, MFS_ProP, Proline/betaine transporter of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli proline/betaine transporter, also called proline porter II (PPII), and similar proteins. ProP is a proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. The ProP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.67934e-107
NZ_LT821227.1|WP_079535620.1|576570_578004_+|nicotinate-phosphoribosyltransferase	gnl|CDD|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
NZ_LT821227.1|WP_079535619.1|575236_576247_+|hypothetical-protein	gnl|CDD|224688	COG1774, COG1774, Uncharacterized homolog of PSP1 [Function unknown].	6.43671e-38

Protein sequences

>NZ_LT821227.1|WP_079535625.1|582866_583985_+|hypothetical-protein
MNSYNTTRKSVFSLLLAAFACLLVVFTLSGCQQTAPEESTSEENASMAGKPLANPTPPAEYSKAVWKVDYVNEEITDDFVHDNWRTSKDEFPEEKVARLGELGLNTEVSRAGMDTLQTIGGADFTSNQFDWILEQVEGMGVTPDKLTVLDLRGESHGLINGDVFMYWISNNYVNESTPTEEVTKIEEDLLDGLKKEGTLEFFQTVNWGAATDLPKLKYENPTIMTEQELVESKGVKYVRFADTNHFRPDDHEVDLFVDFMAGVADDEWLFMHCYAGEGRTTNFMVMTDIYKNYKVASFDDIAARQGLIGPVDVRTEIIETGKTHYKMKASTERRIFLQQFYNYAKDTNFKGKTWTEWCSEKDLTLQYIPPAK
>NZ_LT821227.1|WP_147571517.1|581823_582069_-|hypothetical-protein
MKTKRVSIKKSKLMVGTVVPGIVVPAPLFHRKSGVKKQAIKRKKREHTELTRYYWVLATQKVALHTFRKRQNARTTLMGVI
>NZ_LT821227.1|WP_079535623.1|580584_581262_+|orotate-phosphoribosyltransferase
MEQYKKDFIEFMVNSNALKFGEFTLKSGRKSPYFMNAGAYTTGRQLKQLGEFYAHAINDTFGLDFDVVFGPAYKGIPLSVVTAIAIHELYGKEVRYCSNRKEVKDHGDTGILLGSNLKDGDRVLIVEDVTTSGKSIEETYPIVKAAADVDVIGLEVSLNRCEVGKDTTETALTQVSSLYSMKTSAIVTIHEVAQYLHNREINGEVLIDDATSARMQSYLEEYGAK
>NZ_LT821227.1|WP_079535622.1|579539_580466_+|DegV-family-protein
MRKCNLIIDTACDLPQEYIKADGVTLLRLSYAIEGVSFEDDMFCEQTPHDFYEKIRKGKTPTTSQVSFESFINIFKKAVESGVPTVYLGFTSALSGTFNTASLVRDQIVEQNPGVELYVVDTKLPSIAEGLFVIEAINQMNAGLTATEMVKWANEAKYFIDAQFMVDDLESLKRGGRIPASVAIAGSKLDVKPILTINSDGGLKLVGVARGRKKGVRQLADYFEKRIPDLTSAGAVVIGDADCPKESDKLRDLLLKQNNSLLIVQTNVGPVIGSHVGPGMIAVAFWGRDRRESMSITDRIAKKVKSEN
>NZ_LT821227.1|WP_079535621.1|578020_578923_+|DegV-family-protein
MIRIMCDSVATSDYSELHDLKVDIVSLSVHYDGVDCLDVNMDFDDFNEHLAERALNLPTSSQPSIASFENYFEDAAKKGDLVVGIFMSSVLSSTIEGAIMAANSVKKRFANFECRLIDSFAACGPQMCAILDAVEIRNEGGSIDEIAEAAKRATLRSRIMFTPDDLRFLVLGGRLNAVTAKVASRLKIFPIITTVDGRADALVKVRTKQKADDKMLDVFTRDVREHGLKHVVIHYAGKKTDELKAFSDRVNQLVGIKVKEVSVSPVISVHAGPAIGIAYQCEEEIAGRFTKPNPQIIYAI
>NZ_LT821227.1|WP_079535620.1|576570_578004_+|nicotinate-phosphoribosyltransferase
MNYSLYTDLYQLTMAQGYFLSGKAEQRASFSMNFRKLPFKGGYAVFCGSATLIEMFKNFAFEDDEISYLSSIEAPGGGKLFCKEFLDYLKNMRMSLDMYAPKEGSLVFPYEPIVRVEGPILQCQIVETALLNCINFQTLAATKATRITAAADGRDVAEFGLRRAQGTGSMWGARASYVGGFSSTSNVLAGKEYDIPVSGTHAHSWVMSFDSELESFREYARLFPTNSTLLIDTYSVDEGAKNAIIVAKEMEARGEKMAAVRIDSGDLTWESRRVRKMLDEAGLDYVGIVLSNDLDEYKIESILHEGACVNAFGVGTKYACCYDQPTLGGVYKLNALEENGQWVPKMKISESPEKTTFPGILNIKRFIDDNGQLAGDMVYDENETSLDCTIVDPLNRIKNKKLCGLKGATLLKPIMINGEQVDFWTIHEARDFAKKSFDNLDYSRKRNIYPHIYPVGLELNLSSARDKMISEALHYSK
>NZ_LT821227.1|WP_079535619.1|575236_576247_+|hypothetical-protein
MNLETDLTIDEELKEKEAEAFRVFLELAPSCDEGMEPSFVRYAYDMKKATFYFKSDHRVDFRELVKQLNSRLGISVEMRQIGDREQASLVGGLGPCGQVLCCCRLGNDCCQKNATIKMAKNQNLSLNPTKISGMCGRLMCCLRFENDFYKDFKDRAPKINAQVKTTDGIGKVVAVDALHDLVSVKIDEEKPRQIAVADFKEGSSAENGWKVGRSVWEEAGKALADLTGSAANVTIDTSLFTGNDHMVTSSKAKLASKPATQDNNKKESKPHRRRSRRISSKDTHSRQIVTAKRPGGNSSGIKHASAPKEKIKIERHPHEERKPRRRRTTTINTNKD
>NZ_LT821227.1|WP_079535618.1|574115_575240_+|DNA-polymerase-III-subunit-delta'
MADVFSKIFGQPKVSEFLRRSAAEEHIAQSYLFLGPSGSNKTQAAYALACAFLCGTSKNCAGTCSLRESVLAHKHPDVKFYSPEGESGYLVSQIHEIIHDSTLAPVRGNKKVYILDRVDMLGAFSANAFLKTLEEPTSGTCFILLGRCANSVLPTIRSRCLVVPFRQIPPAQAISIIMQNTIADEQKAKIALSASGNSITAAIKMLTPGDNSLIYLREQIVKIVLGAVVSTDWGVLKAVKDLLLLVKSPTDEYRQRLEESLCDSDDFLSDAAKKQLEKANKRSVKRKESKLINMIFDCIISLMHDVMMILTNDSRRVVNSDFFEELKSFANKTNQIKMVRALDQVISLKNANTYNVSSESLLDLALFEFKGAQE
>NZ_LT821227.1|WP_079535617.1|573396_574092_+|dTMP-kinase
MESKKGIFITFEGSDGVGKSTQVAFFAGLLESLGFDVLLLREPGGTKIGEEIREMLLDVKNKELTSESELLLYLAARSQIINEVIRPALEEGKVVLCDRFSDSTLAYQGYGRGIDAAFIKHANEFVCDGLVPDKTILFYIPEEEQKKRLDRRKAKDRIEEAGKDFALRVAHGFLEIAQEEPKRVEAVCTNGLHSETARHVIKATSDLLGVDPESEKVATALEALDAMHVKK
>NZ_LT821227.1|WP_079535616.1|570871_573382_+|DNA-topoisomerase-I
MHLIITEKNDAAKQIADILASTTAKADKVYNTPVFRFEWNGDECVTIGLRGHILEPNFVDRITWTKSRGWMGESDDVGKVKASIPRNLPKPPFKKKKPFAVDGVDLKGWKMEALPYLIYSPIVKLPKEKEIIRSLKNLAKKSDVIIIATDFDREGELIGKDAMNQCLEVNSEAQFYRARYSSFTKQEITESFSNLVDVDECLASAGATRQDIDLIWGAVLTRYLTLARFAGYGNVRSSGRVQTPTLALIVAKEREREAFIPQDFWVIKAIVDKSKETGPTDNTIEDSADVFECAHSTARFFDKEEADKAFNAVKDATTATVSNIERKKRTVSAPVPFNTTSLMAAASAEGITPARCMRLAESLYMKGFISYPRVDNTVYPKTLNLGEIVSALKVNPAYRPYCDKLLSTGKITATRGKKETTDHPPIYPVKGAVPEDMDASSFKLYNLIARRFLATLSGPATVEGTKISVDINGEAFNKKGDFLVVPGFREIYPYGLKKDEQLPQLEVGQKIAVNETNVTADQTKPPARYSSGRLIQEMEKNGLGTKATRHSIIERLNQVKYIQNDPIEPTQLGIAVIDALGAFAPHITHPEMTAELEDGMDEIVEGKDTREKVVKSSCDHLASELNNLLPHVEEVGEALSDAVSADAYVGKCPKCGKDLQLRASARTKSMFIGCAGWPDCDVTYPLPSGKIETCPDSCPVCGMPQVKVTQFRTKPRLMCINPLCSSNQEPEVFVGKCPTCAKAGIEANLIARRNPKTLKRSVTCENFDNCQTRYPLPPNGEISATDKVCEKCGAPIVCVTTSRGPWELCPNFDCPGKAEEAEKKTKKKAGTSKKKK
>NZ_LT821227.1|WP_079535626.1|584504_586217_-|amidohydrolase
MQNCDFIFRSKKVFTSKKPLKPQDLAIAVRNARILAVDKPEIVCTQFSSKNGTVDFGDSFLCPGFHDAHLHFFHTAIGNSPYMLRCLGKSEADLVEKTKEFAKNLPPDAWVVTQGWRYYRWTPAKYPSKDSIDKAFPDRPCVMYSGDGHTLWLNTCAMNQLGLLQNGASHKEIKTISRSHNGANDNFSLCKTVPAINVQPTKKELQTGIFHEKKAMKLLPFCLEWLGEERIAEAYENEMKRMSSLGITSVCDMSLMPHEGSDFVRDDIFERLNREDKMCLRVHMFPTLLKNKSRLAQLQKKIKECDFLYAPGFKQFFDGVSSEHTAYLTEPYTNARFKEDCGELTIPHKEMRDLVLSAASDKQGVRIHTIGDCAIHFALDIFEEAIEKYGPPETGKNTLEHVENILEEDISRLKECEVVVSSQPCHITLDPGGPERDLGEMRCKLMWPFKTFEKEGITQAFGSDSPITKVSPMDILYTAVTRKDPSTHLPEKGWHPEQNISIAKALQYYTLGSAIAAANERNLGSLEPGKFADFVVLQNDLLTIKAEKIQSNKVLATYLGGKCVYSAKSL
>NZ_LT821227.1|WP_079535627.1|586405_586648_-|hypothetical-protein
MAGTIEHALIFMVGTTYHVSAAVEHASNFMDGTIEHASKIMAGTIEHATNFMAGTIEQSQYFAKTKIKEGRIDINVGDDF
>NZ_LT821227.1|WP_079535628.1|586698_587655_+|acetylglutamate-kinase
MKLAIATQRKGKSALTGEVLSEAMPWIKEITGKTVVIKYGGAALVDSELRRSVLSDILMLKMLGVKPVIVHGGGSAMNDQLRKRNFPVEFIDGQRVTHEESLDFVREVMTGEINQQLVWEMNQHGNIAVGISGIDGGVIVAEPGDPRLKKTGRITRINEGLISGLVEDNYIPVVAAIAIGEDNGVFNVNASLAAGHIASAIGAHKLVFISDVDGLYKNKDNSDSRIANMNKQEAINLLADKCNTTGGSIPKLQSCIHALDKGVYSVHVLNGKIPHVMLVEFLTDEGIGTSISNLGDPETGGRALVNDFASRLIENRCR
>NZ_LT821227.1|WP_079535629.1|588099_589314_+|arginine-deiminase
MPRVNVKSEVRPLSQVILHRPGNELLNLTPNTLEELLFDDIPFLRVAQEEHDAFAKALEDNGVEVLYLEKLVADVFDENPDLRSNFLETWVLEAGVHSDYYKNAIFEYMNSEFKDTLEFVLKTMEGVNIDELDVDLSHSLRAYVIEKSTLIVPPMPNLYFTRDNFAMIGNGVSINHMYSATRNRETIYGDYIFSHHPTYKDVPRYYDRKYPFSIEGGDILNISETCLAVGISQRTEADGIQLLAENIFASDSPIDTILAFEIPNNRSMMHLDTVFTQIDYDKFVVHPGILAPLTVYELSKKGKGIRVTEETMSLKKILKKHVGCKVELIKCGGGNRIVAEREQWNDGSNTLCISPGKVVVYERNDVTNAILEEKGIEVVQIPSAELSRGRGGPRCMSMPAWRED
>NZ_LT821227.1|WP_079535630.1|589575_590571_+|ornithine-carbamoyltransferase
MPVSLSGRHFLKLLDFTTDEINYLLDLSRELKNLKLTGTPHRYLEGKNIVLLFQKTSTRTRCSFEVGAMDLGMGVTYLDPGSSQMGKKESIEDTARVLGRFYDGIEFRGFAQTDVEELAENAGVPVWNGLTTEWHPTQMLADIMTMQEAFNYDIKGKTLVFMGDAANNVARSLMVICSKLGLNFVACCPEANAPGQDVIDACTPIAEENGCTITVTSDVEKAVTGAHCIYTDVWVSMGEPDEVWETRIKDLEPFRVTKEVMEMADKDAIFLHCLPSFHDTNTTIGADIAEKFGVTEMEVTDEVFESPQSKVFEEAENRMHTIKAVMYATLK
>NZ_LT821227.1|WP_079535631.1|590591_591548_+|carbamate-kinase
MAYEKQTNCKTVVIALGGNALGNTPAEQLELVKNTATHIVDMVADDVDIVVSHGNGPQVGMINNAFAYASANDGKTPEIPFPECGAMSQGYIGYHLSQAILNELRERDIKRSSACVVTQTLVDKEDPAFNDPTKPVGAFMTEEDAKAKAEETGLTFKEDAGRGWRQVVASPVPIRIVELDAVKDLVDDGYIVVAGGGGGVPVIEQDGGYHGVPAVIDKDRSSACMAAEFKADMLVILTAVEKVCINFGTPEQEEISEMTISEAREFIKQGHFAPGSMLPKVEACIDYLEKFEGGRALITSLECAAAGIKGETGTVITV
>NZ_LT821227.1|WP_079535632.1|591629_592775_+|serine/threonine-protein-kinase
MAKIVNSWNDWDPLKRVIVGRCDNSVIPPEEPATSEKVPIDSAMRGMWGLRPLDTVERGNECLENLVKILEDRGVIVDRPTPLQWNQAIGTPDFRNDSMFTCMPPRDILLTVGNEIIASANSFRCRYFEYLAYWPLMKQYFDEDPEFLWSQAPRPRLTDKSYKHNYYDEKITLEERLERTAAKDFVTTEIEPMWDAADVMRMGKDFFIQHGLTTNRAAMDWFQRYYPDIRIHAVNFPGDPYPIHIDATFVPLRPGLIINNPVRPLPEEQRAIFEANDWQIVDAAQPAHTEPPPLCYSSVWLSMNCLVLDPKTVIVEASEVHQLEQMDKLGMNVIPCDLRDAYPFGGGLHCSTADVYREGGCEDYFPNRVKDSTLVRPEMWD
>NZ_LT821227.1|WP_079535633.1|593277_594621_+|MFS-transporter
MSEHIVITEEQKQTMLKKVVVSSFLGNFIEWFDYASYSYFAVTIGLVFFPEGDPIVTTMSAFAVFALSYLVRPIGGLFWGNMGDKKGRRWTLSISILVMTTATFLIGCLPGYAMIGLAAPFLLLLCRMTQSFSASGEYAGASTFIAEYAPVKKRGLYVSAVPASTATGLLVGSFFATTMFAICGGADAPFVTEWGWRFPFLIALPLGWITNYIRTHLADSPVYEQMMEEAEAGGKEVGSKTPVRDVIRKYPRTTIICFGSAILNAIGFYAVLTFMPAYLESVLEYDAASAGTITTIVLFAYIAFIFISGWLSDHFGRKKMLLIAAIGFVVCTIPCYMLLATLEFYVILAAELFMALLLCINDGTLASYLSEQFPTEVRFTGFAFTFNLANGLFGGSCSAICLWLVSITGNQLAPGFYFVSIAVLALIAIIFSREQSGTELSEVKIKN
>NZ_LT821227.1|WP_079535634.1|595057_595414_+|transposase
MGRKPRVESSILVHNIGLKGHNSQVVFYDDEDRLKFIECLKESCSRFHVLLLGYVLMNNHVHAFVYAPIGNCASVFESVGATFVRWFNRKYGRSGTIWNGRFCSKPINCRQQLIDTAA
>NZ_LT821227.1|WP_079535635.1|595444_595828_+|hypothetical-protein
MHDARDYRWSSFRELDDPKINPEAYNFLDSVVSVEFLKKYTCERAKMDVEPEIFKQCETIPKDPVSELHLIEIVTRFVKKHNVGRIPSLPENLLRALVKKLLSLGSNVTQISRITGINRRRVVILSS

Crispr_ID: NZ_LT821227_4

• CRISPR_ID: NZ_LT821227_4
• CRISPR_location: 983435-983699
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NZ_LT821227_4

Consensus_repeat	Method
CACTGGTGCCAGNCATGAATTTCTTT	CRT

spacers of NZ_LT821227_4

>4.1|983461|32|NZ_LT821227|CRT
GCGAATAAACTTCTGTGCTCGAGTTGTATTTA
>4.2|983519|39|NZ_LT821227|CRT
CATCAGCATTAGTGCCAGACATGATTTTCTTTAAGTTTG
>4.3|983584|32|NZ_LT821227|CRT
ACGAATAAACTCCTGTGCTCGAGTTGTATTTA
>4.4|983642|32|NZ_LT821227|CRT
ACGTATGTTCTTCCGTGTTTGAATTAAGTTTG

CRISPR arrays and Neighbor proteins around NZ_LT821227_4

CRISPR arrays

The CRISPR arrays of NZ_LT821227_4

>merge|NZ_LT821227|4|983435-983699|CRT
CACTGGTGCCAGTCATGAATTTCTTTGCGAATAAACTTCTGTGCTCGAGTTGTATTTACACTGGTGCCAGACATGAATGTGTGTCATCAGCATTAGTGCCAGACATGATTTTCTTTAAGTTTGCACTGGTGCCAGACATGAATTTCTTTACGAATAAACTCCTGTGCTCGAGTTGTATTTACACTGGTGCCAGTCATGAATTTCTTTACGTATGTTCTTCCGTGTTTGAATTAAGTTTGCACTGGTGCCAGACATGAATTTCTTT

>NZ_LT821227|4|1|983435-983699|CRT
CACTGGTGCCAGTCATGAATTTCTTT	GCGAATAAACTTCTGTGCTCGAGTTGTATTTA
CACTGGTGCCAGACATGAATGTGTGT	CATCAGCATTAGTGCCAGACATGATTTTCTTTAAGTTTG
CACTGGTGCCAGACATGAATTTCTTT	ACGAATAAACTCCTGTGCTCGAGTTGTATTTA
CACTGGTGCCAGTCATGAATTTCTTT	ACGTATGTTCTTCCGTGTTTGAATTAAGTTTG
CACTGGTGCCAGACATGAATTTCTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease	unknown	unknown	gnl|CDD|129986
NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	unknown	unknown	gnl|CDD|225356
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	unknown	unknown	gnl|CDD|374759
NZ_LT821227.1|WP_079535908.1|975991_976180_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	unknown	unknown	gnl|CDD|380149
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535906.1|972129_974583_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535909.1|976640_977177_-|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|153100
NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535905.1|971212_971680_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_LT821227.1|WP_079535911.1|978669_978960_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535912.1|978973_979324_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
NZ_LT821227.1|WP_079535904.1|970719_971031_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293799
NZ_LT821227.1|WP_079535907.1|974647_975766_-|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl|CDD|180601

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	gnl|CDD|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	2.21597e-28
NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease	gnl|CDD|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	1.02925e-55
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.12163e-09
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	gnl|CDD|225356	COG2764, PhnB, Uncharacterized protein conserved in bacteria [Function unknown].	0.00290208
NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.18458e-10
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	gnl|CDD|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	0.00998258
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	gnl|CDD|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.68066e-73
NZ_LT821227.1|WP_079535909.1|976640_977177_-|rubrerythrin-family-protein	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	2.81355e-53
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.14971e-82
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	5.06939e-10
NZ_LT821227.1|WP_079535907.1|974647_975766_-|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl|CDD|180601	PRK06520, PRK06520, 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase.	1.98126e-135

Protein sequences

>NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator
MKKCFDCLSEKGLAETSVRKLAKAAGISAGNIYTYFDSVDDLIIETTNYCAQLIDDDFLKILPNNFENLKEELLNVDYSKLKRNSKKYRFVMNVYISPKYHDSCLKLFKRTDERYDNYTKSVESKIGLPHEVVQPLFFTYANACLYYTLFEDSEHFMKEIEFIAETTEMMREKYKQQQEINNQKN
>NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease
MEELKKKDGAAGVAVGTNARVATDNLGAKLDAANADSKNAVNSQGTDNGSDEKKKPATTKILGPIHIWALGVGIVLVGEFMGWNFTVAKGGSLGSVIALWTVAMMYVTIVMMNTEMGSVMPEAGGQYTMAKYLLGPLAAFIVGLMLVLEYSMLEAADVLVVGQIIESVNPALHSLPFIILALLALTYLNYRGAYATLTLNFIITAVAFCTIMILLISTNFWDPQATLLDLKHLTDGLPYGYIGIIAAMQFAVWFFLGIEGGALAANECRSASRSLPLGTMIGLAVLLIGASLTWFLCSGLVPVDELGVSAFPLYDAALATGKLYVIVALFVGTIMACMASANGCINDASTAWSAMSKDGLIPSVFAKKHPKYKSPYRAIVFLLPISMAFAFTGLLDQVVTFSIFSALMVYVITVVMFFRFRKMYPLGKIKRGYVAPLFPLPAIIAAVLIGMTLLGVYLGYWVNILGGVAFYFLASVWFLVRRNKFVDKKTFLLPGRKQWPKPILGKQESEAAAAAVSAKTAEPATSES
>NZ_LT821227.1|WP_079535912.1|978973_979324_+|hypothetical-protein
MSEKSNSTKNSAGTAAGTKESSMRERVLLVVDIFFVLILCFVVLLITMFCQNLLTSDTEVLAYVLDPKTLIPVILAIAAFVAFLVKMSTKDLKEIVEIEYADAADEGDSDERVVNN
>NZ_LT821227.1|WP_079535911.1|978669_978960_+|hypothetical-protein
MENKVTKKEISKTYHRDCTLLALFAAFMWAIVTMVMFQAESLTSAPGAETIIFAISLTTGIGLTLGLFAVYRHLHNNEDPIYREDIANLKLIKEAE
>NZ_LT821227.1|WP_079535909.1|976640_977177_-|rubrerythrin-family-protein
MSKYAGTQTEKNLQAAFAGESQATNKYNYFASVAKKEGFEQIAEIFRKTSANEQYHAKMWFRELEGIGSTTENLTAAADGENYEWTDMYEEFAKTAEDEGFSELAEKFRQVGQIEKHHEERYRKLLHNVEAKEVFEKSEVKIWECRNCGHIIIGTKAPDVCPVCNHPQSYFEISAENF
>NZ_LT821227.1|WP_079535908.1|975991_976180_-|hypothetical-protein
MGNLIKALFIKGVIGVIFAVICYIGFFVDGDLADFMGGAMPGILLGFCLLDLLIAPRETKEK
>NZ_LT821227.1|WP_079535907.1|974647_975766_-|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MNNLHAPFKYDFVGSFLRPAELKEARANFEEGKIDANELKNTEDKCITELISKIKSCGYHIITDGEFRRATWHLDFMWGFDGVDHIKTKTGLPFHGEAAMIDDTFLTGKIELNGEHPFIDHFRFVKKFEDENTVAKQTIPSPAQTLAQFWMPFSRPATQEFYSTEEDLENDIADAYIKVLHQLYDAGCRNVQFDDCTWGMMADQKGHELYGTTQVGLIDVQKAHKNINNKVIAGVPDDMVVNTHVCRGNFHSTYANSGAYDSVADILFREENVNAYYLEFDDERSGGFAPLAKVSDNKQVVLGLITTKSPELEDKETVISRIHEAEKYIPLDRLCLSPQCGFASCEIGNKLTEDEQWAKLALVKEIAEEVWG
>NZ_LT821227.1|WP_079535906.1|972129_974583_+|hypothetical-protein
MSISPKRVKRKLARVALVVALIGLGNIVYTAFPCLGPVTAYADTNSSSELVVDDNYPSLDGWIANKLGTASIIKITTSSCGVSDSGTKATTIPAQVKKLTGWQQYFWESEGKPYNRQLGYAGGNEMLTFEVGSSTEVNSLSLKLQNDKLVVPAGANITFKNCTFTSRIKIDKGGRATFENCVFATGTILNNGQANYSGSTQEPKNEGKAESAFEDLKLTSSETSFDNAMKGYAYKQDVPLVISGTNSDTAEITAQLDQVESGLFASINENTLTISGTPKKAGLVKVTVTATASDEAGTGTQTSSVDVILNVSQRYTFSLEGTLDAVRSGQGDYADSTNSKLKVVVTSEDGTQQGFYDFSTSDSGKDVDLKPFISPDGSGLSAYVFNSAAGSELSLSGTAGEAGTYDVGAIVNFKGQTLKTNTVQLRIYSGNETLKSQLSTLNGNISEWDMEPYEIDRSDNAVIPKTLRHIFGSHQSGLYGQIGNATDEFASDTLTVPAGTDVTLENIKVNSSVKITVEKGGKLTLTDSAVYGPVEVNGGTLTMNNSASNMSTITLNNGSTLKDSEIVSHAQFLTDGRKPTQPAPAHVVSVNGKVNFEGNNSIKADQSQIGLEVKGIAHILEGSKLSITGGNEGTAPGNAESAINLINGTIDGKGTLQAIGGTYEVGGSGTPAKAVKGKGKLSTAKLILAGGDANSIFNTKINGANAGTKDVTVTTPANGRTIKGGKGVNGGADGLGEESLTIADNDLEQKPSVESDATQGNTTSSMASTKESTATKATPIIPQTGDGTVQLVAAAAIIGFVSLLAAVAFALRRHLKI
>NZ_LT821227.1|WP_079535905.1|971212_971680_-|hypothetical-protein
MTQLLSRRTFLMLTSASIASLAFGCKASEKSDSEWMWAQDDELDVLSMQVAGGAIVAIHGNGWKPQDGWIQVQLSGGSVPGKEIEKIWQEGSTLVVKLKKPSSIAETMDIRLTEFRVSGGDVSSIDSVEIIDKNERTKAELGVDTEPDNQQNSDL
>NZ_LT821227.1|WP_079535904.1|970719_971031_-|hypothetical-protein
MKLLQISEGIRPELNYISSVRRDSFKDFEEAYLKYDDMLEKFGNMISHKRMLQAKNDLKNWLSSQLIDNPKMGDLPAEKPYILKTPRIVRWAFISWDKTGQHM
>NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein
MNGVFGNTFDFNRNGNIDPFERAAEYSLVNHILDGNDKFTRLSDKHEHSYNSSFEGESNTTTDFPSSSSDIDEDDTWLNDSDDDDFCLDDSDNDNWLDDLDDDDWPIDTDEDGSLAGNYDFSEATDFIFNKKECESADNTSAEKRSSQEDDFGYTEPDFLKKSCASDVSSDSKVANVCDESTSNEFDSFCLDYVSSGISPGYSSSSNIDNQPPSDSSDLDIDAYNIEKYPLGSKLGYFKEPIEKGSIVHPDVKVNLLTSLMYGVKKIPYEAHKKMQKAGALCFKDRIKLWEERRDYLLEHHFDFDRLSKMSKKDALDMIKQAGLNPYDYWDMF
>NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein
MACFIVGGAEAVVVTAVRSAVKKSEERRGIVDESGKQISDPAEHGICWTRKISWLMNMLWGGVILLCVEHMWHGEVVPFTPFLTAMSDPAEIPVMLHEMATVGVAMCVMVTVVWFVATVVADMAVKRSIHFAEKEV
>NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein
MTLFITLCAASIATLVWYCTAPSSGLKTGVLALMYWGAALMWTVDGIANLIEGEAFVEIADTAVMLEDAMLGFFVVVSGLVAWTIYLCIKDPKKVFRKALS
>NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMVKRAENYKWSSFKDLDSEEFDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDGKEFEVIPSSTPSDMLVIDAVKRIVKEKNLGRISALSSSLLRKLVKSLLKLGSNINQIFRVTGLTRHQVSILAT
>NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein
MAVLYVADFRIQLISIKPNSYPPNETTYLELIRASTVTYNNIQFMSGTIASRLSVLHACY
>NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator
MKTNKPEISMNKKLLNENSAPYVYSIALMGIFTFLFLGTEYLCVDVLSRLALGNEVVLAQNYTLGISAIGFLLFPLLKRFRNGKTISAVYTAVGAVSIAYIAFLCANLDYTMTSVIGFALFLLLGFLGSAVFYISARMLNSNKYLARITGISYAIGILLQFANNNLAHEEIAEAFVYCAFLVLLVYILIKADKKLRSNNATYSTHLEQTISINASFEKTKNVLIAMTVLLISLMTCIFSSLDNAVTLKHATGVVDVGQWPRILLALSGLGAGFIFDLKKRKYMGIVMYCVMVFSTICILLMKLSGPILASLIVFYLSTGFFAVFFTTTFMDLSQYMKMPELWAGMGRALNNITAAIIANPILWILSSDNYLASLILMLLLFIAVSVITAVCTTRKIALLREIKKKIDEDKSEEKKLKVITAKYSLTDREAEVLLQLVSTEDSIQTIAENLFISRRTLERHITSIYEKTNIKSRIGLANLYNMRQ
>NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase
MDTPKISRRGFLGGSAAAVASLALAACSSNSGEEKKEGEEKPFTPQTDFSETTGDKLKITTLSENTNTGHESLSAEFGFCALIELGDSKVLFDTAKKGDFIEHAQELHADIANTKMIVLSHAHYDHCGGLMKYLNMFDGKGRTLYLKDCFFDGAAEKYYDDIAGQKLDFTDGTPGYFNIGIKFDQKDVEATGAKVEYMTGDSMELAPGITLYGNFVRNPLDPKMLIKNDKGEYIIDNFDEEVAISVETSKGIIVVSGCSHTGIENIVKAIKDRTGKDVYAVIGGFHLLDATEKQIQNSIDTFSGLGVSHMGVSHCIGEKAKKMFCEQLPDIAFVNTTGSVFEMK
>NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein
MDLKLLRFGRFAVVSICALLLALLVSLSGCSGSENQDSDKQEQSSEQTENKGSEDSKKDGEKEADESENHPMVQTYEKIRKLPKEEITSLTYDDIVATYFDGVEGTLAGEKDNGEVVYKWKSDDGKASIQITFENVDGVLYCTRYHSLYQYK
>NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein
MKYEIVGAPFSVVVCELEAGEKVKTEMGSMAWMDPVFQMETSGGGMKKMFGKMMSGEGLFENIYTATSAGKIAFGSSFPGSIMPVDISPGNEVIVQKSSFLASDMGVDISIFFNRKLGAGFFGGEGFVMQKLSGNGKAFLEIDGSFIEYELAAGQQLIVDTGNVMGFTGGVTMDIQQVKGIKNKLLGGEGIFNTRLTGPGTVWIQTMPMASFVESIMPFIQPGNK
>NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein
MSLKRFSVLISGTICLLIACTLFGCSGGESADSGSSSNATTENAKEANNVFNIGDYTAEFTKAEIGEDAGGEPALLVHYKFTNNSKDSQSFIWAFTNKAFQNGVQLDTATVWKSEGSFDTVSDSTFSDIQPGISLDVCETYVLQDTTTPVTVEVTGLLSDKKKSFEINPAELDEFTPGA

Crispr_ID: NZ_LT821227_5

• CRISPR_ID: NZ_LT821227_5
• CRISPR_location: 992438-992636
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NZ_LT821227_5

Consensus_repeat	Method
CACTGGTGCCAGTCATGAATGTGAA	CRISPRCasFinder

spacers of NZ_LT821227_5

>5.1|992463|39|NZ_LT821227|CRISPRCasFinder
GCTTTTACAACGGTGCCAGACATGAATGTATGTTATCAG
>5.2|992527|29|NZ_LT821227|CRISPRCasFinder
ATTCAATTGCTCTTTCATTGGTGTTTTTA
>5.3|992581|31|NZ_LT821227|CRISPRCasFinder
ACAGATGACAGACATGAATGTGTGTCATCGG

CRISPR arrays and Neighbor proteins around NZ_LT821227_5

CRISPR arrays

The CRISPR arrays of NZ_LT821227_5

>merge|NZ_LT821227|5|992438-992636|CRISPRCasFinder
CACTGGTGCCAGTCATGAATGTGAAGCTTTTACAACGGTGCCAGACATGAATGTATGTTATCAGCACTGGTGCCAGTCATGAATGTCGAATTCAATTGCTCTTTCATTGGTGTTTTTACACTGGTGTCAGACATGAATTTTACACAGATGACAGACATGAATGTGTGTCATCGGCACTGGTGCCAGACATGATTTGTGA

>NZ_LT821227|5|4|992438-992636|CRISPRCasFinder
CACTGGTGCCAGTCATGAATGTGAA	GCTTTTACAACGGTGCCAGACATGAATGTATGTTATCAG
CACTGGTGCCAGTCATGAATGTCGA	ATTCAATTGCTCTTTCATTGGTGTTTTTA
CACTGGTGTCAGACATGAATTTTAC	ACAGATGACAGACATGAATGTGTGTCATCGG
CACTGGTGCCAGACATGATTTGTGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536917.1|997978_998695_+|SAM-dependent-methyltransferase	unknown	unknown	unknown
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	unknown	unknown	gnl|CDD|225356
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	unknown	unknown	gnl|CDD|374759
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	unknown	unknown	gnl|CDD|380149
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293799
NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease	unknown	unknown	gnl|CDD|129986
NZ_LT821227.1|WP_079535911.1|978669_978960_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535929.1|996593_996791_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
NZ_LT821227.1|WP_079535912.1|978973_979324_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536921.1|1001529_1001640_+|thioredoxin	unknown	unknown	unknown
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	5.06939e-10
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.12163e-09
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	gnl|CDD|225356	COG2764, PhnB, Uncharacterized protein conserved in bacteria [Function unknown].	0.00290208
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	gnl|CDD|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	0.00998258
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	gnl|CDD|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.68066e-73
NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease	gnl|CDD|129986	TIGR00908, putative_ethanolamine_permease, ethanolamine permease. The three genes used as the seed for this model (from Burkholderia pseudomallei, Pseudomonas aeruginosa and Clostridium acetobutylicum are all adjacent to genes for the catabolism of ethanolamine. Most if not all of the hits to this model have a similar arrangement of genes. This group is a member of the Amino Acid-Polyamine-Organocation (APC) Superfamily. [Transport and binding proteins, Amino acids, peptides and amines].	1.02925e-55
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	gnl|CDD|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	2.21597e-28
NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.74926e-07
NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.44193e-51
NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.18458e-10
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.14971e-82
NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.23696e-70

Protein sequences

>NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator
MKTNKPEISMNKKLLNENSAPYVYSIALMGIFTFLFLGTEYLCVDVLSRLALGNEVVLAQNYTLGISAIGFLLFPLLKRFRNGKTISAVYTAVGAVSIAYIAFLCANLDYTMTSVIGFALFLLLGFLGSAVFYISARMLNSNKYLARITGISYAIGILLQFANNNLAHEEIAEAFVYCAFLVLLVYILIKADKKLRSNNATYSTHLEQTISINASFEKTKNVLIAMTVLLISLMTCIFSSLDNAVTLKHATGVVDVGQWPRILLALSGLGAGFIFDLKKRKYMGIVMYCVMVFSTICILLMKLSGPILASLIVFYLSTGFFAVFFTTTFMDLSQYMKMPELWAGMGRALNNITAAIIANPILWILSSDNYLASLILMLLLFIAVSVITAVCTTRKIALLREIKKKIDEDKSEEKKLKVITAKYSLTDREAEVLLQLVSTEDSIQTIAENLFISRRTLERHITSIYEKTNIKSRIGLANLYNMRQ
>NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein
MAVLYVADFRIQLISIKPNSYPPNETTYLELIRASTVTYNNIQFMSGTIASRLSVLHACY
>NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMVKRAENYKWSSFKDLDSEEFDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDGKEFEVIPSSTPSDMLVIDAVKRIVKEKNLGRISALSSSLLRKLVKSLLKLGSNINQIFRVTGLTRHQVSILAT
>NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein
MTLFITLCAASIATLVWYCTAPSSGLKTGVLALMYWGAALMWTVDGIANLIEGEAFVEIADTAVMLEDAMLGFFVVVSGLVAWTIYLCIKDPKKVFRKALS
>NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein
MACFIVGGAEAVVVTAVRSAVKKSEERRGIVDESGKQISDPAEHGICWTRKISWLMNMLWGGVILLCVEHMWHGEVVPFTPFLTAMSDPAEIPVMLHEMATVGVAMCVMVTVVWFVATVVADMAVKRSIHFAEKEV
>NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein
MNGVFGNTFDFNRNGNIDPFERAAEYSLVNHILDGNDKFTRLSDKHEHSYNSSFEGESNTTTDFPSSSSDIDEDDTWLNDSDDDDFCLDDSDNDNWLDDLDDDDWPIDTDEDGSLAGNYDFSEATDFIFNKKECESADNTSAEKRSSQEDDFGYTEPDFLKKSCASDVSSDSKVANVCDESTSNEFDSFCLDYVSSGISPGYSSSSNIDNQPPSDSSDLDIDAYNIEKYPLGSKLGYFKEPIEKGSIVHPDVKVNLLTSLMYGVKKIPYEAHKKMQKAGALCFKDRIKLWEERRDYLLEHHFDFDRLSKMSKKDALDMIKQAGLNPYDYWDMF
>NZ_LT821227.1|WP_157887294.1|981910_982468_-|TetR-family-transcriptional-regulator
MKKCFDCLSEKGLAETSVRKLAKAAGISAGNIYTYFDSVDDLIIETTNYCAQLIDDDFLKILPNNFENLKEELLNVDYSKLKRNSKKYRFVMNVYISPKYHDSCLKLFKRTDERYDNYTKSVESKIGLPHEVVQPLFFTYANACLYYTLFEDSEHFMKEIEFIAETTEMMREKYKQQQEINNQKN
>NZ_LT821227.1|WP_079535913.1|979421_981008_+|amino-acid-permease
MEELKKKDGAAGVAVGTNARVATDNLGAKLDAANADSKNAVNSQGTDNGSDEKKKPATTKILGPIHIWALGVGIVLVGEFMGWNFTVAKGGSLGSVIALWTVAMMYVTIVMMNTEMGSVMPEAGGQYTMAKYLLGPLAAFIVGLMLVLEYSMLEAADVLVVGQIIESVNPALHSLPFIILALLALTYLNYRGAYATLTLNFIITAVAFCTIMILLISTNFWDPQATLLDLKHLTDGLPYGYIGIIAAMQFAVWFFLGIEGGALAANECRSASRSLPLGTMIGLAVLLIGASLTWFLCSGLVPVDELGVSAFPLYDAALATGKLYVIVALFVGTIMACMASANGCINDASTAWSAMSKDGLIPSVFAKKHPKYKSPYRAIVFLLPISMAFAFTGLLDQVVTFSIFSALMVYVITVVMFFRFRKMYPLGKIKRGYVAPLFPLPAIIAAVLIGMTLLGVYLGYWVNILGGVAFYFLASVWFLVRRNKFVDKKTFLLPGRKQWPKPILGKQESEAAAAAVSAKTAEPATSES
>NZ_LT821227.1|WP_079535912.1|978973_979324_+|hypothetical-protein
MSEKSNSTKNSAGTAAGTKESSMRERVLLVVDIFFVLILCFVVLLITMFCQNLLTSDTEVLAYVLDPKTLIPVILAIAAFVAFLVKMSTKDLKEIVEIEYADAADEGDSDERVVNN
>NZ_LT821227.1|WP_079535911.1|978669_978960_+|hypothetical-protein
MENKVTKKEISKTYHRDCTLLALFAAFMWAIVTMVMFQAESLTSAPGAETIIFAISLTTGIGLTLGLFAVYRHLHNNEDPIYREDIANLKLIKEAE
>NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase
MDTPKISRRGFLGGSAAAVASLALAACSSNSGEEKKEGEEKPFTPQTDFSETTGDKLKITTLSENTNTGHESLSAEFGFCALIELGDSKVLFDTAKKGDFIEHAQELHADIANTKMIVLSHAHYDHCGGLMKYLNMFDGKGRTLYLKDCFFDGAAEKYYDDIAGQKLDFTDGTPGYFNIGIKFDQKDVEATGAKVEYMTGDSMELAPGITLYGNFVRNPLDPKMLIKNDKGEYIIDNFDEEVAISVETSKGIIVVSGCSHTGIENIVKAIKDRTGKDVYAVIGGFHLLDATEKQIQNSIDTFSGLGVSHMGVSHCIGEKAKKMFCEQLPDIAFVNTTGSVFEMK
>NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein
MDLKLLRFGRFAVVSICALLLALLVSLSGCSGSENQDSDKQEQSSEQTENKGSEDSKKDGEKEADESENHPMVQTYEKIRKLPKEEITSLTYDDIVATYFDGVEGTLAGEKDNGEVVYKWKSDDGKASIQITFENVDGVLYCTRYHSLYQYK
>NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein
MKYEIVGAPFSVVVCELEAGEKVKTEMGSMAWMDPVFQMETSGGGMKKMFGKMMSGEGLFENIYTATSAGKIAFGSSFPGSIMPVDISPGNEVIVQKSSFLASDMGVDISIFFNRKLGAGFFGGEGFVMQKLSGNGKAFLEIDGSFIEYELAAGQQLIVDTGNVMGFTGGVTMDIQQVKGIKNKLLGGEGIFNTRLTGPGTVWIQTMPMASFVESIMPFIQPGNK
>NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein
MSLKRFSVLISGTICLLIACTLFGCSGGESADSGSSSNATTENAKEANNVFNIGDYTAEFTKAEIGEDAGGEPALLVHYKFTNNSKDSQSFIWAFTNKAFQNGVQLDTATVWKSEGSFDTVSDSTFSDIQPGISLDVCETYVLQDTTTPVTVEVTGLLSDKKKSFEINPAELDEFTPGA
>NZ_LT821227.1|WP_079535929.1|996593_996791_+|hypothetical-protein
MNLKETLASEICLYKVTIYNGARHELKLPFTLVPDILLLHVIYKAVKCKKAMKPFENVGSSVYEA
>NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase
MKLRVKNIKCIAGQCAEVKELFNSAFPQCERIPYWLLCLFTLRKKVHLLAFYDDEAFVGLMLTYDHCSYFYIAYLAVNPKIRSKGYGGAILNFAFEIADSKTLVLEVELPEPNSENLEQRNRRISFYKKHGICDSGFRYSDKGVTYAILTSDPVNFSATKFKKLLRDFYLGCFKKKLEKF
>NZ_LT821227.1|WP_079536917.1|997978_998695_+|SAM-dependent-methyltransferase
MADECLICGAPLKYLEADENIQCSLCYKWETSKTCCVNGHYVCNECHTKGMGAIMSICLRSTSKNPIEIVQQMMDEPWCHMHGPEHHVMVGAALLAAYRNAGGDIDLETALHEMMSRGKKVPGGTCGFWGACGAGISTGMFVAIVTKSNPLAQKQWALSNEVTSQSLACIAEHGGPRCCKRDSFHAILSAIDFVAENLGVQMEKPNIICKYFSKNNQCLGENCVFNPKAVKAKQINSR
>NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein
MNKLSLQWRITIMTTLLIGITCVLMKVLLCSSGIHYMDAIGNSVIDSAPIASDSPGFFNPNTISDKRGLSIVISNAQEEFCMTNWYITAIVTIVSGILAWFVSGRALRPLRKFTNQVETVQLHNIAEIRINENTVPEFRQLGQSFNAMLERLNNAFSAQKQFTGNAAHELRTPVALMQAQVELFEAEHPDIPKEYREFTTQIKEQTERLTQTIKTLLDMSSMQSVARNDVVQIAPLVEEIFADLSPEASKKDIAFSLEGDAEIKGSDTLIYRMIYNLCENAIKFNRPNGGVFVRVIEDETLKAKTDSMREYKKSDQRLTIEVEDCGFGIPKEFQRSIFQPFFRVDKSRSRENGGVGLGMSLVWEIVSLHGGRVFVKESDENGTTIAVELPV
>NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor
MHLLVVEDERVLCDTIVRSLRRKAYSVDFCHDGERALDMLRNETFDLVVLDLNLPKIDGISVLRRLRSFDKETKVLILSARSEVADKVEGLDSGANDYLSKPFHLAELEARIRSLTLRQFTQKDVLLTCGEVEFDTRTRKAIANGIELSLTRKETGILEYLMAHQGRPVSQEELIEHVWDNSVDAFSNSIRVHISALRKKLRATLEHDPIKNRIGEGYVIEEKF
>NZ_LT821227.1|WP_079536921.1|1001529_1001640_+|thioredoxin
MLAAAIAMLLAGSLQGEVQVVLSKAIKLCLECVGIG

Crispr_ID: NZ_LT821227_6

• CRISPR_ID: NZ_LT821227_6
• CRISPR_location: 996376-996470
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_6

Consensus_repeat	Method
TTACAATGGTGCCAGTCATGAATGTA	CRISPRCasFinder

spacers of NZ_LT821227_6

>6.1|996402|43|NZ_LT821227|CRISPRCasFinder
AACGAGTCATAATTTTTAATCTCTTGCCTGTATATCGATGCTA

CRISPR arrays and Neighbor proteins around NZ_LT821227_6

CRISPR arrays

The CRISPR arrays of NZ_LT821227_6

>merge|NZ_LT821227|6|996376-996470|CRISPRCasFinder
TTACAATGGTGCCAGTCATGAATGTAAACGAGTCATAATTTTTAATCTCTTGCCTGTATATCGATGCTATTACACTGGTGCCAGTCATGAATGTA

>NZ_LT821227|6|5|996376-996470|CRISPRCasFinder
TTACAATGGTGCCAGTCATGAATGTA	AACGAGTCATAATTTTTAATCTCTTGCCTGTATATCGATGCTA
TTACACTGGTGCCAGTCATGAATGTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
NZ_LT821227.1|WP_079536923.1|1002855_1003770_+|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl|CDD|239264
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	unknown	unknown	gnl|CDD|225356
NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	unknown	unknown	gnl|CDD|380149
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	unknown	unknown	gnl|CDD|376704
NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein	unknown	unknown	gnl|CDD|223715
NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536917.1|997978_998695_+|SAM-dependent-methyltransferase	unknown	unknown	unknown
NZ_LT821227.1|WP_079535929.1|996593_996791_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	unknown	unknown	gnl|CDD|374759
NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NZ_LT821227.1|WP_079535936.1|1001632_1002586_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|223425
NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079535939.1|1004472_1005447_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|184456
NZ_LT821227.1|WP_079536921.1|1001529_1001640_+|thioredoxin	unknown	unknown	unknown
NZ_LT821227.1|WP_079535941.1|1005717_1008771_+|VaFE-repeat-containing-surface-anchored-protein	unknown	unknown	gnl|CDD|375630
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|293799
NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	5.06939e-10
NZ_LT821227.1|WP_079536923.1|1002855_1003770_+|TlpA-family-protein-disulfide-reductase	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.37525e-27
NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.12163e-09
NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein	gnl|CDD|225356	COG2764, PhnB, Uncharacterized protein conserved in bacteria [Function unknown].	0.00290208
NZ_LT821227.1|WP_079535941.1|1005717_1008771_+|VaFE-repeat-containing-surface-anchored-protein	gnl|CDD|375630	pfam18202, TQ, T-Q ester bond containing domain. This domain is found in gram positive bacterial surface proteins. It contains a very unusual isopeptide bond between a conserved N-terminal threonine residue on the first beta strand of the Ig-like fold and and a glutamine residue in the final strand of the domain.	4.6308e-32
NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein	gnl|CDD|380149	NF012181, MSCRAMM_SdrD, MSCRAMM family adhesin SdrD. Features of this protein family include a YSIRK-type signal peptide at the N-terminus and a variable-length C-terminal region of Ser-Asp (SD) repeats followed by an LPXTG motif for surface immobilization by sortase.	0.00998258
NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	1.14971e-82
NZ_LT821227.1|WP_079535939.1|1004472_1005447_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	5.05384e-105
NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein	gnl|CDD|374759	pfam16729, DUF5067, Domain of unknown function (DUF5067).	2.21597e-28
NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.74926e-07
NZ_LT821227.1|WP_079535936.1|1001632_1002586_+|4Fe-4S-binding-protein	gnl|CDD|223425	COG0348, NapH, Polyferredoxin [Energy production and conversion].	6.27604e-21
NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.44193e-51
NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase	gnl|CDD|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.68066e-73
NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.23696e-70

Protein sequences

>NZ_LT821227.1|WP_079535925.1|995717_996257_+|DUF5067-domain-containing-protein
MSLKRFSVLISGTICLLIACTLFGCSGGESADSGSSSNATTENAKEANNVFNIGDYTAEFTKAEIGEDAGGEPALLVHYKFTNNSKDSQSFIWAFTNKAFQNGVQLDTATVWKSEGSFDTVSDSTFSDIQPGISLDVCETYVLQDTTTPVTVEVTGLLSDKKKSFEINPAELDEFTPGA
>NZ_LT821227.1|WP_079535922.1|995018_995696_+|TIGR00266-family-protein
MKYEIVGAPFSVVVCELEAGEKVKTEMGSMAWMDPVFQMETSGGGMKKMFGKMMSGEGLFENIYTATSAGKIAFGSSFPGSIMPVDISPGNEVIVQKSSFLASDMGVDISIFFNRKLGAGFFGGEGFVMQKLSGNGKAFLEIDGSFIEYELAAGQQLIVDTGNVMGFTGGVTMDIQQVKGIKNKLLGGEGIFNTRLTGPGTVWIQTMPMASFVESIMPFIQPGNK
>NZ_LT821227.1|WP_079535920.1|994400_994859_+|hypothetical-protein
MDLKLLRFGRFAVVSICALLLALLVSLSGCSGSENQDSDKQEQSSEQTENKGSEDSKKDGEKEADESENHPMVQTYEKIRKLPKEEITSLTYDDIVATYFDGVEGTLAGEKDNGEVVYKWKSDDGKASIQITFENVDGVLYCTRYHSLYQYK
>NZ_LT821227.1|WP_079536915.1|992853_993888_+|MBL-fold-metallo-hydrolase
MDTPKISRRGFLGGSAAAVASLALAACSSNSGEEKKEGEEKPFTPQTDFSETTGDKLKITTLSENTNTGHESLSAEFGFCALIELGDSKVLFDTAKKGDFIEHAQELHADIANTKMIVLSHAHYDHCGGLMKYLNMFDGKGRTLYLKDCFFDGAAEKYYDDIAGQKLDFTDGTPGYFNIGIKFDQKDVEATGAKVEYMTGDSMELAPGITLYGNFVRNPLDPKMLIKNDKGEYIIDNFDEEVAISVETSKGIIVVSGCSHTGIENIVKAIKDRTGKDVYAVIGGFHLLDATEKQIQNSIDTFSGLGVSHMGVSHCIGEKAKKMFCEQLPDIAFVNTTGSVFEMK
>NZ_LT821227.1|WP_147571542.1|990875_992330_-|helix-turn-helix-transcriptional-regulator
MKTNKPEISMNKKLLNENSAPYVYSIALMGIFTFLFLGTEYLCVDVLSRLALGNEVVLAQNYTLGISAIGFLLFPLLKRFRNGKTISAVYTAVGAVSIAYIAFLCANLDYTMTSVIGFALFLLLGFLGSAVFYISARMLNSNKYLARITGISYAIGILLQFANNNLAHEEIAEAFVYCAFLVLLVYILIKADKKLRSNNATYSTHLEQTISINASFEKTKNVLIAMTVLLISLMTCIFSSLDNAVTLKHATGVVDVGQWPRILLALSGLGAGFIFDLKKRKYMGIVMYCVMVFSTICILLMKLSGPILASLIVFYLSTGFFAVFFTTTFMDLSQYMKMPELWAGMGRALNNITAAIIANPILWILSSDNYLASLILMLLLFIAVSVITAVCTTRKIALLREIKKKIDEDKSEEKKLKVITAKYSLTDREAEVLLQLVSTEDSIQTIAENLFISRRTLERHITSIYEKTNIKSRIGLANLYNMRQ
>NZ_LT821227.1|WP_147571540.1|990330_990513_-|hypothetical-protein
MAVLYVADFRIQLISIKPNSYPPNETTYLELIRASTVTYNNIQFMSGTIASRLSVLHACY
>NZ_LT821227.1|WP_079535918.1|988946_989717_+|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMVKRAENYKWSSFKDLDSEEFDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDGKEFEVIPSSTPSDMLVIDAVKRIVKEKNLGRISALSSSLLRKLVKSLLKLGSNINQIFRVTGLTRHQVSILAT
>NZ_LT821227.1|WP_079535917.1|987533_987839_+|hypothetical-protein
MTLFITLCAASIATLVWYCTAPSSGLKTGVLALMYWGAALMWTVDGIANLIEGEAFVEIADTAVMLEDAMLGFFVVVSGLVAWTIYLCIKDPKKVFRKALS
>NZ_LT821227.1|WP_079535916.1|987122_987533_+|hypothetical-protein
MACFIVGGAEAVVVTAVRSAVKKSEERRGIVDESGKQISDPAEHGICWTRKISWLMNMLWGGVILLCVEHMWHGEVVPFTPFLTAMSDPAEIPVMLHEMATVGVAMCVMVTVVWFVATVVADMAVKRSIHFAEKEV
>NZ_LT821227.1|WP_079535915.1|984163_985165_+|hypothetical-protein
MNGVFGNTFDFNRNGNIDPFERAAEYSLVNHILDGNDKFTRLSDKHEHSYNSSFEGESNTTTDFPSSSSDIDEDDTWLNDSDDDDFCLDDSDNDNWLDDLDDDDWPIDTDEDGSLAGNYDFSEATDFIFNKKECESADNTSAEKRSSQEDDFGYTEPDFLKKSCASDVSSDSKVANVCDESTSNEFDSFCLDYVSSGISPGYSSSSNIDNQPPSDSSDLDIDAYNIEKYPLGSKLGYFKEPIEKGSIVHPDVKVNLLTSLMYGVKKIPYEAHKKMQKAGALCFKDRIKLWEERRDYLLEHHFDFDRLSKMSKKDALDMIKQAGLNPYDYWDMF
>NZ_LT821227.1|WP_079535929.1|996593_996791_+|hypothetical-protein
MNLKETLASEICLYKVTIYNGARHELKLPFTLVPDILLLHVIYKAVKCKKAMKPFENVGSSVYEA
>NZ_LT821227.1|WP_079535931.1|996780_997323_+|GNAT-family-N-acetyltransferase
MKLRVKNIKCIAGQCAEVKELFNSAFPQCERIPYWLLCLFTLRKKVHLLAFYDDEAFVGLMLTYDHCSYFYIAYLAVNPKIRSKGYGGAILNFAFEIADSKTLVLEVELPEPNSENLEQRNRRISFYKKHGICDSGFRYSDKGVTYAILTSDPVNFSATKFKKLLRDFYLGCFKKKLEKF
>NZ_LT821227.1|WP_079536917.1|997978_998695_+|SAM-dependent-methyltransferase
MADECLICGAPLKYLEADENIQCSLCYKWETSKTCCVNGHYVCNECHTKGMGAIMSICLRSTSKNPIEIVQQMMDEPWCHMHGPEHHVMVGAALLAAYRNAGGDIDLETALHEMMSRGKKVPGGTCGFWGACGAGISTGMFVAIVTKSNPLAQKQWALSNEVTSQSLACIAEHGGPRCCKRDSFHAILSAIDFVAENLGVQMEKPNIICKYFSKNNQCLGENCVFNPKAVKAKQINSR
>NZ_LT821227.1|WP_147571544.1|999126_1000302_-|HAMP-domain-containing-protein
MNKLSLQWRITIMTTLLIGITCVLMKVLLCSSGIHYMDAIGNSVIDSAPIASDSPGFFNPNTISDKRGLSIVISNAQEEFCMTNWYITAIVTIVSGILAWFVSGRALRPLRKFTNQVETVQLHNIAEIRINENTVPEFRQLGQSFNAMLERLNNAFSAQKQFTGNAAHELRTPVALMQAQVELFEAEHPDIPKEYREFTTQIKEQTERLTQTIKTLLDMSSMQSVARNDVVQIAPLVEEIFADLSPEASKKDIAFSLEGDAEIKGSDTLIYRMIYNLCENAIKFNRPNGGVFVRVIEDETLKAKTDSMREYKKSDQRLTIEVEDCGFGIPKEFQRSIFQPFFRVDKSRSRENGGVGLGMSLVWEIVSLHGGRVFVKESDENGTTIAVELPV
>NZ_LT821227.1|WP_079535933.1|1000464_1001139_-|response-regulator-transcription-factor
MHLLVVEDERVLCDTIVRSLRRKAYSVDFCHDGERALDMLRNETFDLVVLDLNLPKIDGISVLRRLRSFDKETKVLILSARSEVADKVEGLDSGANDYLSKPFHLAELEARIRSLTLRQFTQKDVLLTCGEVEFDTRTRKAIANGIELSLTRKETGILEYLMAHQGRPVSQEELIEHVWDNSVDAFSNSIRVHISALRKKLRATLEHDPIKNRIGEGYVIEEKF
>NZ_LT821227.1|WP_079536921.1|1001529_1001640_+|thioredoxin
MLAAAIAMLLAGSLQGEVQVVLSKAIKLCLECVGIG
>NZ_LT821227.1|WP_079535936.1|1001632_1002586_+|4Fe-4S-binding-protein
MDSKKTTVSKLLSRRRGWVQAGATVVTNIHLPNFIDGSLYKGAGKSVCVPGLNCYSCPAATGACPIGAFQSVVGNSKFSFSYYVTGTLILLGVLLGRFICGFLCPFGWFQDLLHKIPSKKISTTKLKPLRLLKYAVLLFSVVLLPALLVNDVGLGEPIFCKYICPQGVLEGAIPLSIVDSGIRATLGLLFEWKFTILVVLILLSVFIYRPFCKWICPLGAIYGLMNRVSMTQMNVDKNKCVSCGKCARACKMDVDVTKTPNHFECIRCGMCVTACPTDAVSIRFGLGDAKTPSTKVPGQKIKHKNAIDNAVDKGARA
>NZ_LT821227.1|WP_079536923.1|1002855_1003770_+|TlpA-family-protein-disulfide-reductase
MNKLSIGLAALFAAVLLITLSACGKQQEKMGGSSMDSMSYEEAAKMYDELTEEENQILTENKELWEKVFMAGTKDMAKIQETKNYGDFLLNTIEAAKDEFSDDEYQMITGEAEKIKEIENKLIMLTEKFPELAKRKTDGGTSVPAENGEVKKFPTFEGKDLDGNQVKSDELFGNSKVSVMNFWFTTCNPCVRELPDLESLNGELKSKGGQVVGVNSFTLDGDQQAINEAKDVLNKKDVTYKNVYFDSNSEAGKFTNKINGFPTTIVVDRNGNIVGDPIVGPITEQKQKDALMKLVDQAIANDKM
>NZ_LT821227.1|WP_079535939.1|1004472_1005447_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MKLKHIPILLSLGFLLGGCSFVQSNDCLSETLGDADFNSKTTEEASEEKMKTPESTNEIYLAGGCFWGMELLMESIPGVVDAQSGYANGNSAEAANYKSVCSGDTGFRETVRVKYDPGQVSLDGILLAYFYVIDPTVENRQGNDRGSQYQTGIYYVDDESKETVERIAEIERWRHDKFVVEICPLKNYYPAEDYHQDYLKKNPRGYCHIPRKEIELFSKLKIDPGDYQKPAEESIREKLTNEQYRVTQNGGTETAFKNAFWNQFEQGIYVDVVTGEPLFSSTDKFHSGCGWPAFSKPIETPAVVEKEDLRSSLWRLVYSGSIIP
>NZ_LT821227.1|WP_079535941.1|1005717_1008771_+|VaFE-repeat-containing-surface-anchored-protein
MNKLVKRLLTGTLAFATILTALPVTAVHASGNQYWTESAERVGYIEHVMNDGSIKSTFNEGHMKVEGETAYCVDINTNFKNGYKTRSDASTRMSSDQIADVALSLEYVKQYTASHTNLNYKQGYLLEQCVVWQRLSEQLGWQCDNVRASYNEISQAVQNEVYAGAKAFVKANKGRYECGGYIYTGEGQDIGQFWAKLNVGNAKVKKTSSNPTVTDGNANYSFEGATFGVYSDKSCNSQLATLTADGNGDTKEVEVKAGTVYIKELSAPKGYKLDSTVHALNVEVGKTATLTVADTPKVTETLIDLLKIDMETGKSTPQGTASLEGAEFTWSYYDGYYNTDNLPAKATRTWTTKTVAEKESDGTIYYVSRLADNYKVSGDSFYTQDGKNVLPLGTLTVTESKAPNGYLLDGAYMQADESSEQIKGTYLTQISEDGELAVLSGSNQYSVSDKVIRGGVKIQKRDLETKDTKAQGSATLQYTEFNIISLNDSPVLVEGKLYNKNETVKKIQTGINGIASTSADLLPYGNYRLEESKAPEGYLTDGAKAIDFSITEDGKIVDLTDKSHSVYNQIKRGDIEGVKIGAGTHKRLAGVPFRITSKTTGESHIVVTDNNGQFSTASSWASHKVNTNAGKSSEDGVWFGTSEPDDSKGALLYDTYVIEELKCDSNAGFKLIPAFEVVVSRNKVTVDLGTLTDEYEKEITIHTTATDKKTGEKMIVAGKDIKIVDKVTLDGLEVGTKYKLSGWQMLKEENAELLIDGKRVDSDYTFTADSEKMTVEITYSFDGSALGGQNLVTFEELYDMSNPKEPVKVAEHKDINDDGQTVLITERIVKIHTTATDKNGKKEIEAGKDVTIVDKVTLDGLEVGTKYKLSGWQMLKEENAELLIDGKKVSNDYEFTADNEKMTVEIAFTFDGSSLGGKSLVTFEELYDMTNPDEPKKVTEHKDITDDGQTVTIKEVPEVPDTPKDTDTPDTPSTVTKTSDSPKTGDNTNIYAYLAMLGLSCVGLGGMLYFKHRKKKS

Crispr_ID: NZ_LT821227_7

• CRISPR_ID: NZ_LT821227_7
• CRISPR_location: 1332229-1332320
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_7

Consensus_repeat	Method
GGAGAGAATGTAGAAGCTAGTCTTGT	CRISPRCasFinder

spacers of NZ_LT821227_7

>7.1|1332255|40|NZ_LT821227|CRISPRCasFinder
AACGCTCTTTACGATTCCAACATCAACAGGTTAGTACACT

CRISPR arrays and Neighbor proteins around NZ_LT821227_7

CRISPR arrays

The CRISPR arrays of NZ_LT821227_7

>merge|NZ_LT821227|7|1332229-1332320|CRISPRCasFinder
GGAGAGAATGTAGAAGCTAGTCTTGTAACGCTCTTTACGATTCCAACATCAACAGGTTAGTACACTGGAGATAATGTAGAAGCTAGTCTTGT

>NZ_LT821227|7|6|1332229-1332320|CRISPRCasFinder
GGAGAGAATGTAGAAGCTAGTCTTGT	AACGCTCTTTACGATTCCAACATCAACAGGTTAGTACACT
GGAGATAATGTAGAAGCTAGTCTTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536623.1|1343705_1344734_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536587.1|1325850_1326723_-|rhodanese-like-domain-containing-protein	unknown	unknown	gnl|CDD|238089
NZ_LT821227.1|WP_162273047.1|1336853_1337045_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_LT821227.1|WP_079536592.1|1328061_1328784_+|epoxyqueuosine-reductase-QueH	unknown	unknown	gnl|CDD|376894
NZ_LT821227.1|WP_079536574.1|1313891_1315040_-|sensor-histidine-kinase	unknown	unknown	gnl|CDD|340424
NZ_LT821227.1|WP_079536594.1|1328773_1329862_+|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl|CDD|234666
NZ_LT821227.1|WP_079536590.1|1326862_1328008_-|tRNA-guanosine(34)-transglycosylase-Tgt	unknown	unknown	gnl|CDD|234642
NZ_LT821227.1|WP_079536580.1|1321895_1323104_-|tyrosine--tRNA-ligase	unknown	unknown	gnl|CDD|235645
NZ_LT821227.1|WP_147571556.1|1315036_1315714_-|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|223816
NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|319971
NZ_LT821227.1|WP_079536977.1|1335027_1336080_-|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270270
NZ_LT821227.1|WP_079536585.1|1324032_1325745_+|phospho-sugar-mutase	unknown	unknown	gnl|CDD|100092
NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein	unknown	unknown	gnl|CDD|223462
NZ_LT821227.1|WP_079536571.1|1312786_1313611_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NZ_LT821227.1|WP_162273048.1|1341047_1341341_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536601.1|1334019_1335000_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein	unknown	unknown	gnl|CDD|377215
NZ_LT821227.1|WP_162273046.1|1323206_1323473_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase	unknown	unknown	gnl|CDD|223363

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536587.1|1325850_1326723_-|rhodanese-like-domain-containing-protein	gnl|CDD|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	8.49408e-20
NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.73134e-26
NZ_LT821227.1|WP_079536592.1|1328061_1328784_+|epoxyqueuosine-reductase-QueH	gnl|CDD|376894	pfam02677, DUF208, Uncharacterized BCR, COG1636.	2.35129e-69
NZ_LT821227.1|WP_079536574.1|1313891_1315040_-|sensor-histidine-kinase	gnl|CDD|340424	cd16948, HATPase_BceS-YxdK-YvcQ-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.	3.8007e-33
NZ_LT821227.1|WP_079536594.1|1328773_1329862_+|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl|CDD|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	0
NZ_LT821227.1|WP_079536590.1|1326862_1328008_-|tRNA-guanosine(34)-transglycosylase-Tgt	gnl|CDD|234642	PRK00112, tgt, queuine tRNA-ribosyltransferase; Provisional.	0
NZ_LT821227.1|WP_079536580.1|1321895_1323104_-|tyrosine--tRNA-ligase	gnl|CDD|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	4.18165e-176
NZ_LT821227.1|WP_147571556.1|1315036_1315714_-|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.99998e-55
NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl|CDD|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	4.00088e-59
NZ_LT821227.1|WP_079536977.1|1335027_1336080_-|extracellular-solute-binding-protein	gnl|CDD|270270	cd13552, PBP2_Fbp_like_6, Substrate binding domain of an uncharacterized ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. This periplasmic domain (Fbp) has high affinity for ferric iron and serves as the primary receptor for transport. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.2011e-101
NZ_LT821227.1|WP_079536585.1|1324032_1325745_+|phospho-sugar-mutase	gnl|CDD|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein	gnl|CDD|223462	COG0385, COG0385, Predicted Na+-dependent transporter [General function prediction only].	3.81979e-94
NZ_LT821227.1|WP_079536571.1|1312786_1313611_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.05613e-98
NZ_LT821227.1|WP_079536601.1|1334019_1335000_-|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.00152e-137
NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein	gnl|CDD|377215	pfam04071, zf-like, Cysteine-rich small domain. Probable metal-binding domain.	9.29764e-20
NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase	gnl|CDD|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	7.00278e-28

Protein sequences

>NZ_LT821227.1|WP_079536594.1|1328773_1329862_+|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MLTSDFDYELPEKLIAQTPAEVRDECRMLVLHKDSGEIEHKIFKDIVDYVNPGDLLIANETRVIPARLIGKKRGTGGVCEILLLRPMIENKVNSKVAKWEALVRPGKRLKPGSDAVIEFFDIKGNVAIKARIIDWAKDLKNAQKGERVVELTTELPSLDEALHEVGKVPLPPYIHDYSGDEEMYQTVYSKHEGSAAAPTAGLHFTPELIFKCEEKGVGWATVDLEVGLDTFRLVDEENAEDHAMHTETYSVPESTVNAINETRANGGRIFAVGTTSVRSLESCFLRTSSIEPCCRAATSLYLMPGSHFNVVDAMITNFHVPKSTLMMLVSAFAGRDNIMNAYEEAKKVGYRFLSFGDAMLLV
>NZ_LT821227.1|WP_079536592.1|1328061_1328784_+|epoxyqueuosine-reductase-QueH
MAMSPTKTQSNENTSFLLHACCGPCSLEPIRILRDRGIEPVVFYSNSNIAPLEEYERRRDTIRDWCKMHDVSFIEDDYSPCEWKEATKGLLAQKPNRCRECYRIRFERAAKFAKQNGFRGLGTTLTISPYQYTLTIKEELKKACEKEDIDCFFKDYSTHYRAAQKRAKEEGLYRQNYCGCLPSKAEAEAEKKRTKAIKAKRQQEREEKLQKQREEKADYAKKRAKQREILKKMREERDAH
>NZ_LT821227.1|WP_079536590.1|1326862_1328008_-|tRNA-guanosine(34)-transglycosylase-Tgt
MSLFDCRIDAVCGHARALTYETAHGNFQTPMFMPVGTSATVKGITPKVLKELNSQVVLANTYHLSMRPGADLIAEAGGVHKFMNYDGPMLTDSGGFQVFSLADTVKLDEDGVTFKSIYDGHRVKWTPEENMAIQQKIGADIVMQLDQCAPYPAEKDFVARAVELSSMWAKRCLASHTKKDQTLFGIVQGGMHLDLRLQSINSLIEIENESMANGGRRFGGFGIGGYSVGEDHETMFETLGEVARALPQDRPRYLMGVGNPTTLVRAVGEGVDMFDCVLPTRTARMGTAFSSKGRMNMRNAKFEHDFTPLDHECDCYTCKNFTRAYIRHLVKQNEMLGSILLSIHNIHFLLDLMRRARAAVIAGNYSEFLSAWLNSEGANDY
>NZ_LT821227.1|WP_079536587.1|1325850_1326723_-|rhodanese-like-domain-containing-protein
MTISKKFMSAFIVVALACGLSLGLVACSSGSTEEKKEETTTTEVKEVEMKQEAVDVAKDEVGKSDVVFLDVRKADDYAAGHIIGAVNADMDKAKDGDNESGIANMKEAIEKNNLKDQKLVLACYSGKRYAQAATNILNALGYDMSKVVTLEGGMKAWDAAGLPKATDVKDVEMKQEAVDTAKGEVGQSDVVFVDCRKADDFKAGHIEGAINADMDKAKDGDTTDGLVNISKAIQDNNLSDQKLVLVCYSGKRYAQAATNSLSALGYDMSKVVTLEGGMKAWDAAGYDKVQ
>NZ_LT821227.1|WP_079536585.1|1324032_1325745_+|phospho-sugar-mutase
MKFEKTAREWADKTKCENMRNQLLSWIEEGNEAAIEDAFFQDLEFGTAGLRGIIGPGTNRMNANTVARATQGVADYLNAHYKKPSVAIAHDSRNKGERFTEITASVLAANGITAHVFPRLEPTPALAYATQFLHCDAGICITASHNPKEYNGYKVFNSKGCQITSQVASDMSDAIKKLDYFDGIKKIDFEDGIKSGKIKWINDECINSFVKDAVNNVNNIDKDAMKNLCLAYSPLNGTGLEPVIKAFEMIGVKNVHIVEEQKNPDENFPTCSKPNPEERSALELGIKLVDDVDADLLIATDPDADRTGIAVRHNGECELVSGNEVGLLMMNHFASQCSRNEIKNKIFCTTLVSTSMADALAKYYGFELRRVPTGFKYIGEQITKLEEKREKNRFVMGFEESYGYLVGTHVRDKDSISATVTICDMAAKCKKKGKDLIDALTALYEEFGYYKNSTTSYSFPGADGSEKMKNIMASLRGNAPTEIDGKKVVQFIDYKEETKMSILNSRDREEQILPRVNVLQFDLEDEAKVIIRPSGTEPKIKAYTFVKGTSTDDASKKLEELNATVNEYFK
>NZ_LT821227.1|WP_162273046.1|1323206_1323473_-|hypothetical-protein
MNSHRLLVRGHRVPYDENDETKEALNSTVGPFTNYAMWIFRSLAVVALFAVVVMKRSRDCQQLERLRTILLHKQKRLNTGLVFSLSIK
>NZ_LT821227.1|WP_079536580.1|1321895_1323104_-|tyrosine--tRNA-ligase
MLSAEEQMHIIKSGVAQIVPEDELLKKLKSGRSLRIKLGVDPTAPDIHIGHAVPLRKLRQFQDLGHTVVLIIGNGTALIGDPSGRNTTRPQLSSEEIAKNAQTYVDQAFKILDPEKTELRFNADWILSVDTKKLLELMSKFTVARILERDDFHNRYTNNQPISLHEFLYPVMQAFDSVEINADVELGGTDQLFNLLAGRELMEKCDMEPQVALTMPLLEGTDGVRKMSKSYGNYIGLTDKPEDIFGKCMSIPDEMIVKYCRLASSFSVEKCDAIEAGLEDGSVDPYKTKRELAANLVASYYDEEAAKAAEEHFDVVCKQGDVPDDIESYEGELKVNDEGNVYLAALLAEIKFAQSASDARRLIDSGAVKIGDDVVPAKAYNINPTDLKGKVLRSGKRKFMQF
>NZ_LT821227.1|WP_147571556.1|1315036_1315714_-|winged-helix-turn-helix-domain-containing-protein
MAKIFIIEDDVVLRTELRRILELNNYEVEIFEGDDFKKSSSAALSSNCDLLISDLKLSGFDGLKVCKEIKEENPNISILVLTSSDSEFDEIFSMHIGVDDYVTKPYSVPVLLAHIERVIKNAQPLLNEDFISCDKLKIYPSKFKIQLGDQEVDLSKNEMKILLVLTRAKGDVISRQDLMYELWQTEKFVDDNTLTVNVNRLRKTLKEIGAGDDFIKTVRGEGYRI
>NZ_LT821227.1|WP_079536574.1|1313891_1315040_-|sensor-histidine-kinase
MTFFKFCRSRIEYLIALIAIVVFADVFLCMVEASGSYVFLFSLVALFVFIVVFTCSYFKNRDVFRSIEAISQLDSYTFDCMNSFPNIRTSEQELIYEAIEAVIISSTSAISEMEARNSEYQEFIEAWVHEIKTPLAAAFLLADHLPSSDKVQISGELDSIKYLIDQVLWYARNDSVNKDYSVARVNLCELINSCVSSNARFLIEKHVSPKNKVEQGDVVYSDAKWLSFILSQLVINAAKYGAKTINFYTEENYGFSSCNACGVSEHINSLGQLDSNEDFPKCSSGVSEEPLRQSAISKTQLVIEDDGWGILPEDLSKVYEKGFVGKNGRIVGHSTGIGLYLVKSLCDKLGLSLEIESQAGIGTKARITFPINRDIAATNYQQ
>NZ_LT821227.1|WP_079536571.1|1312786_1313611_-|ABC-transporter-ATP-binding-protein
MLFKRKGTVVVQDSNFVSTSIDCNDALLSVTDLKKIYGRGEAATHALCGLTFNVCDGEFVGVMGSSGSGKSTLLNCISTIDVPTSGKIVLGGQNVCTLRSSQLSKFRRENIGFIFQNANLIETLTGAENIALALSLKGVSSAEIESRVQTVASTLGVSSVLDKMPNEMSGGERQRVSAARAIVGDPKIILADEPTGALDSKNTTILLETLEHINKSSHSTILMVTHDAYAAGFTDRTIFLKDGKIFCETTKGSKSRKDYYKDIVNVLALLGSEA
>NZ_LT821227.1|WP_079536601.1|1334019_1335000_-|ABC-transporter-ATP-binding-protein
MSGIAIKDLSFSYGEADVLKNINLDIKEGEFHSLLGLSGCGKTTLLRLVAGFLTPSKGKILLDGRDITNLAPEKRNMGIVFQNYALFLHMSVAENVAYGLKVDKVPASEITKRVDEYLDLLNMSEFKNRNVRELSGGQQQRVALARALARGVDVLLLDEPMSNLDISLREKMRVELKNIQQQIGITTLLITHEQSEALSISDSVSVMNNGVIEQTGTPYEIYESPNTDFLRTFVGDMNVFDAGSQWSTFDHIDANGKVFIRPEHLVVSRDPSECAIEGIVKRVKYEGAIIQCFVEVGNQLVKVMMLNTKTACKFKPGDTAFVSEAK
>NZ_LT821227.1|WP_079536977.1|1335027_1336080_-|extracellular-solute-binding-protein
MASALSAALCCFALVGCAGQSSDSSSDNEQLEDKLVIYSTHPEALLQEVADDFTAETGVPVEFINLKGGLADRVLSEKDNPQADIMYGGSTTTFTELAKQGCYEKTNPSWANELDSNFKDKDGQWYATIQTPVVMFYNTEMMSEADAPKNYNDLADSKYADQVVTRDNASSSQREWICAMIYANSKDGNMDKANEWLKGLASNTKNYYNSSSMMFKAIGNKEAAIGVSTLNDVQKNIEKNGMPLKAIDSSDGNVISVDCVAALKNAPHSKAAAKFVEFCGTAKEQAKIANSQSRIPTLKSALKDSPEWMQKEMKMLDVDTATIASHQSEWLDLWNNTAYDTSKVVEAEKK
>NZ_LT821227.1|WP_162273047.1|1336853_1337045_+|hypothetical-protein
MLSGKTVHYEVSLSEYRTKHEFRIPVVGKNGRTKKVLAVYQIDKGSMIQGMIANFPESKRKWR
>NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein
MKTLEKISDFAGKYMAFIALAVTVIALIIPGPTHTILPTSWVNPLLGIVMFGMGMTLKLSDFKVVFIKPKAVITGIFSQFIIMPFLAWVLCLIFQLPTELAVGVILVGCCPGGTSSNVMTYLSKGDVALSVGMTACTTIMAPVVTPALVLLLAGQTINVSYVSMLMSIVQVVLVPIVLGFLINAVAPKVSEVFGKVLPLISVIAISLIIMAVVSANAAKIMTSGLLIIAVVMLHNVLGYALGYGVGRALHLSKAQVRTLSIEVGMQNSGLATSLALTHFASMPLAAVPGTVFSVWHNISGAVYANILAATAGKTSDAKQEGAEEENTNNQAADKKASAHA
>NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein
MNVTHDEQLVFTHSDCPYYPCHSIAEGVKFNCIFCYCPLYALGPNCGGDFCYLDDGTKDCSKCTIMHEGAKGFERVREKFPELEDLAKA
>NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MNSPKSVHRVLFVCHGNICRSPSAEFIFKDIVMSHGVESDYKIESAATSNDEIWNGVGSPVYPQAAELLKRHGIACEGKRARKMVKSDYDNFDLLLGMDNANISEMKRIAGGDGDHKIHLLLEYTNNPHEISDPWYTRDFEKAYSEINQGCEALFIKLNS
>NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase
MPGHEKRVLSLDGLRGLGALMVFLYHVDIMVKPFGAGGPSLFPGTASVMVFFILSGIVLSLVPFKHMGNGGYNWLGYYPRRVVRLCGPLFVAIALALPAGYVAWRLGSTSRSALAVAYDAGLPTAVHDILMQFDVLFNVSDGVNNLFGAHLVRVDSPVWSMSWELWFSLTLPLAIWCISRIHRTGLAVVATFIAVLVSHWTGYFPLRFCLMFWLGVMVARRFDKIKAVKLSMLAELALLVASVGVIELSLVWHPGGVLEALKSTAMNAACLVVVVVAIADGFTRRALSAAPMVFLGKVSYSLYLTHAIVIGVLVALLPRLGIVDPLAIAAVSLPASMLVSVAFWRIIEVPSMNLSRSLASSGPRDAVR
>NZ_LT821227.1|WP_162273048.1|1341047_1341341_-|hypothetical-protein
MTVVIVADITPHPLRTKADSVQKIVGYAGTGVMLVAISVMVPNVERPDCLPLFLLQAAFVLASAVVYGLLVKESALVQRMPQKSLEMGIREEAAEAD
>NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase
MVAAYEQFTHSVLKRQQGQFFTNRLVVRAMVHMLNPSITDAVLDPAGGSGGFATEAFRHKRRKVIESTIEGTAQRERQLERSKNMVFLVEISQRLVKIAKTAMLLSGDGNSGMTQGNSLDEYSNLDGWITSHCPRHTPDVIVTNPPFSGQKTESMMMDPEILKLFSFGHKPTSDGIFPEIGGKDDWEANRGTILSRQAPELLFLERCIDWLKPGGRIGIVLPKGILDNQTYVNYRKWVLSNCKVDAVVTLHKNTFEPDTGVRTCILFLSKPSEGEEVPSDYTIFMAQSRRVGRDSKGEPVFSLDEKGHATDVLDEDLTQISDSYETVKANGTFIESETCFSAKRSELDDNLNLNPQHYSPELNATLERVNEFDEKEGWSVTTIGQLDKDIHIYMGPRWNSRSLVVENPDDTTGLTPYLTANGALEQRRMTVKWFDMSRATAKKRDCVEKLRVRHGNICRSSQSQTTREACRCLSAPS
>NZ_LT821227.1|WP_079536623.1|1343705_1344734_+|hypothetical-protein
MQIHYFQRYHSKENVDTSNTMLMLSRLYNYNADKFFSMLNSLILGEDESPEITFDLQVVGDDSVPDAVISQKSFKIVVETKLYNQFYKQQLVNHLEQFGAEDIKVLLTLDPKPMKPQLFDELAVELKKYNSENATRLIHPIKHVNLTFEQLMDAMEDIVDDRDTEIIAVLDDFKKYCFDEKLIPDGYKWMRATVASTTFQDNMDLDLFYDRESRNFSEHGYIGLYKDKSIRAIGKLKKTVIAVENNGSMTYRAESGAEPTTDEIERINEAIRRADNYGYNLRTISHRYFIVEKFYPMDFRKSSKNPIQKSKLFNLADMFGYKTMPDTDVIANDLNGRTWEEF

Crispr_ID: NZ_LT821227_8

• CRISPR_ID: NZ_LT821227_8
• CRISPR_location: 1348525-1348611
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_8

Consensus_repeat	Method
CACTAATGAATCATGTCTGGCAC	CRISPRCasFinder

spacers of NZ_LT821227_8

>8.1|1348548|41|NZ_LT821227|CRISPRCasFinder
CAATTAGCATGACTAAGCATGACTAGGGGGGTAATGTCTGA

CRISPR arrays and Neighbor proteins around NZ_LT821227_8

CRISPR arrays

The CRISPR arrays of NZ_LT821227_8

>merge|NZ_LT821227|8|1348525-1348611|CRISPRCasFinder
CACTAATGAATCATGTCTGGCACCAATTAGCATGACTAAGCATGACTAGGGGGGTAATGTCTGACACTAATGAATCACGTCTGGCAC

>NZ_LT821227|8|7|1348525-1348611|CRISPRCasFinder
CACTAATGAATCATGTCTGGCAC	CAATTAGCATGACTAAGCATGACTAGGGGGGTAATGTCTGA
CACTAATGAATCACGTCTGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536623.1|1343705_1344734_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536628.1|1346830_1347256_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase	unknown	unknown	gnl|CDD|223363
NZ_LT821227.1|WP_079536653.1|1360422_1360752_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536648.1|1356028_1357540_-|alanine:cation-symporter-family-protein	unknown	unknown	gnl|CDD|376500
NZ_LT821227.1|WP_079536637.1|1349637_1350030_-|riboflavin-kinase	unknown	unknown	gnl|CDD|376594
NZ_LT821227.1|WP_079536658.1|1363368_1364451_-|3-phosphoserine/phosphohydroxythreonine-transaminase	unknown	unknown	gnl|CDD|235428
NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein	unknown	unknown	gnl|CDD|377215
NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase	unknown	unknown	gnl|CDD|319971
NZ_LT821227.1|WP_079536640.1|1350732_1351503_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079536635.1|1348661_1349303_-|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl|CDD|223200
NZ_LT821227.1|WP_079536633.1|1347747_1348410_-|hypothetical-protein	unknown	unknown	gnl|CDD|379388
NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein	unknown	unknown	gnl|CDD|223462
NZ_LT821227.1|WP_079536655.1|1361670_1363248_-|phosphoglycerate-dehydrogenase	unknown	unknown	gnl|CDD|237436
NZ_LT821227.1|WP_162273048.1|1341047_1341341_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536625.1|1345517_1346816_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase	unknown	unknown	gnl|CDD|224748
NZ_LT821227.1|WP_079536650.1|1358298_1360413_-|heavy-metal-translocating-P-type-ATPase	unknown	unknown	gnl|CDD|319848
NZ_LT821227.1|WP_079536645.1|1354855_1355560_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213222
NZ_LT821227.1|WP_079536643.1|1352240_1354844_-|FtsX-like-permease-family-protein	unknown	unknown	gnl|CDD|226957

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536628.1|1346830_1347256_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00838047
NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.73134e-26
NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase	gnl|CDD|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	7.00278e-28
NZ_LT821227.1|WP_079536648.1|1356028_1357540_-|alanine:cation-symporter-family-protein	gnl|CDD|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NZ_LT821227.1|WP_079536637.1|1349637_1350030_-|riboflavin-kinase	gnl|CDD|376594	pfam01687, Flavokinase, Riboflavin kinase. This family represents the C-terminal region of the bifunctional riboflavin biosynthesis protein known as RibC in Bacillus subtilis. The RibC protein from Bacillus subtilis has both flavokinase and flavin adenine dinucleotide synthetase (FAD-synthetase) activities. RibC plays an essential role in the flavin metabolism. This domain is thought to have kinase activity.	9.01597e-43
NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein	gnl|CDD|377215	pfam04071, zf-like, Cysteine-rich small domain. Probable metal-binding domain.	9.29764e-20
NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase	gnl|CDD|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	4.00088e-59
NZ_LT821227.1|WP_079536635.1|1348661_1349303_-|DNA-3-methyladenine-glycosylase-2-family-protein	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	4.59715e-51
NZ_LT821227.1|WP_079536633.1|1347747_1348410_-|hypothetical-protein	gnl|CDD|379388	pfam13828, DUF4190, Domain of unknown function (DUF4190). This integral membrane domain is functionally uncharacterized. One of the membrane helices contains two GXXG motifs that are usually associated with dimerization.	1.31555e-05
NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein	gnl|CDD|223462	COG0385, COG0385, Predicted Na+-dependent transporter [General function prediction only].	3.81979e-94
NZ_LT821227.1|WP_079536655.1|1361670_1363248_-|phosphoglycerate-dehydrogenase	gnl|CDD|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NZ_LT821227.1|WP_079536658.1|1363368_1364451_-|3-phosphoserine/phosphohydroxythreonine-transaminase	gnl|CDD|235428	PRK05355, PRK05355, 3-phosphoserine/phosphohydroxythreonine transaminase.	0
NZ_LT821227.1|WP_079536625.1|1345517_1346816_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	6.8539e-35
NZ_LT821227.1|WP_079536640.1|1350732_1351503_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.99642e-09
NZ_LT821227.1|WP_079536650.1|1358298_1360413_-|heavy-metal-translocating-P-type-ATPase	gnl|CDD|319848	cd07550, P-type_ATPase_HM, P-type heavy metal-transporting ATPase; uncharacterized subfamily. Uncharacterized subfamily of the heavy metal-transporting ATPases (Type IB ATPases) which transport heavy metal ions (Cu(+), Cu(2+), Zn(2+), Cd(2+), Co(2+), etc.) across biological membranes. The characteristic N-terminal heavy metal associated (HMA) domain of this group is essential for the binding of metal ions. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NZ_LT821227.1|WP_079536645.1|1354855_1355560_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.9668e-95
NZ_LT821227.1|WP_079536643.1|1352240_1354844_-|FtsX-like-permease-family-protein	gnl|CDD|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	1.4335e-06

Protein sequences

>NZ_LT821227.1|WP_079536633.1|1347747_1348410_-|hypothetical-protein
MEDVQNFNGSGENKSKSVLAIVALILAIIALIISWVPILNNFSFIIAILAAIFGVVAVVSVSKSHGRKSGKSIAIASIVVAAIAAVVVLASQAAYSSSVDEASRQLQDSADKMTGDATEQLLNTDIDVSLGDFTASPTTYGTYDTKLVVTATNKNSEAKSYSIKVEAVDSDGKRIKDDTAYFNQLGSNQSQDVEIFKFVSTDDVESLQGATFKIMSVSQY
>NZ_LT821227.1|WP_079536628.1|1346830_1347256_-|helix-turn-helix-transcriptional-regulator
MSFKEPLTEELLGKILESDSIEDLSVPKAYSRRTFAEYFCELLEIKRKKRVDVIREAGIDATFGYQIFKGQRNPSRDKVLSLCLALDCTLRETNRALKISGANELYSKNRRDVIIIFAIEHNFSFQRTNEALYEFEEPTLN
>NZ_LT821227.1|WP_079536625.1|1345517_1346816_-|protein-kinase
MKITAVKDSHSEKKDSSEKQDIFCKTSCSSARATSAYSEELRQLLESFDQDGVRVEETFKESSNETTQRVLYAGKQCIRKVIKTGGRRTGYDLLFDLQREGVPLQFVPRILDLKQGSDSEVVFIEYLEVPSLRDLILVEPLSRDAVNNIFLKICDAVIELHSQNLPIIHRDIKPSNILTNGTNVWIIDFGISRAYDALQNSDTTVFGTQGFAPPEQFGFGQTDVRSDLYQLAQTYYFMVAGHQAEKPLTKIENLDELFGKNVANVLRKASSFDPDMRQPNVLQFKQEILIALQNDSTAAASAGTFRGIVLEVREALRGKFQSAGIIWNAFLVVLFIVLFYVCCKLAFVPQPPSVSSTPTADFAFNVAIYIIGFVPFCFFILFAFYDKRRISKRLKFFQEHAVIKSLALIGIGIAWIFSVASLLVALFYFRPI
>NZ_LT821227.1|WP_079536623.1|1343705_1344734_+|hypothetical-protein
MQIHYFQRYHSKENVDTSNTMLMLSRLYNYNADKFFSMLNSLILGEDESPEITFDLQVVGDDSVPDAVISQKSFKIVVETKLYNQFYKQQLVNHLEQFGAEDIKVLLTLDPKPMKPQLFDELAVELKKYNSENATRLIHPIKHVNLTFEQLMDAMEDIVDDRDTEIIAVLDDFKKYCFDEKLIPDGYKWMRATVASTTFQDNMDLDLFYDRESRNFSEHGYIGLYKDKSIRAIGKLKKTVIAVENNGSMTYRAESGAEPTTDEIERINEAIRRADNYGYNLRTISHRYFIVEKFYPMDFRKSSKNPIQKSKLFNLADMFGYKTMPDTDVIANDLNGRTWEEF
>NZ_LT821227.1|WP_172618946.1|1341373_1342807_-|N-6-DNA-methylase
MVAAYEQFTHSVLKRQQGQFFTNRLVVRAMVHMLNPSITDAVLDPAGGSGGFATEAFRHKRRKVIESTIEGTAQRERQLERSKNMVFLVEISQRLVKIAKTAMLLSGDGNSGMTQGNSLDEYSNLDGWITSHCPRHTPDVIVTNPPFSGQKTESMMMDPEILKLFSFGHKPTSDGIFPEIGGKDDWEANRGTILSRQAPELLFLERCIDWLKPGGRIGIVLPKGILDNQTYVNYRKWVLSNCKVDAVVTLHKNTFEPDTGVRTCILFLSKPSEGEEVPSDYTIFMAQSRRVGRDSKGEPVFSLDEKGHATDVLDEDLTQISDSYETVKANGTFIESETCFSAKRSELDDNLNLNPQHYSPELNATLERVNEFDEKEGWSVTTIGQLDKDIHIYMGPRWNSRSLVVENPDDTTGLTPYLTANGALEQRRMTVKWFDMSRATAKKRDCVEKLRVRHGNICRSSQSQTTREACRCLSAPS
>NZ_LT821227.1|WP_162273048.1|1341047_1341341_-|hypothetical-protein
MTVVIVADITPHPLRTKADSVQKIVGYAGTGVMLVAISVMVPNVERPDCLPLFLLQAAFVLASAVVYGLLVKESALVQRMPQKSLEMGIREEAAEAD
>NZ_LT821227.1|WP_079536614.1|1339766_1340873_-|acyltransferase
MPGHEKRVLSLDGLRGLGALMVFLYHVDIMVKPFGAGGPSLFPGTASVMVFFILSGIVLSLVPFKHMGNGGYNWLGYYPRRVVRLCGPLFVAIALALPAGYVAWRLGSTSRSALAVAYDAGLPTAVHDILMQFDVLFNVSDGVNNLFGAHLVRVDSPVWSMSWELWFSLTLPLAIWCISRIHRTGLAVVATFIAVLVSHWTGYFPLRFCLMFWLGVMVARRFDKIKAVKLSMLAELALLVASVGVIELSLVWHPGGVLEALKSTAMNAACLVVVVVAIADGFTRRALSAAPMVFLGKVSYSLYLTHAIVIGVLVALLPRLGIVDPLAIAAVSLPASMLVSVAFWRIIEVPSMNLSRSLASSGPRDAVR
>NZ_LT821227.1|WP_079536611.1|1339247_1339730_-|low-molecular-weight-phosphotyrosine-protein-phosphatase
MNSPKSVHRVLFVCHGNICRSPSAEFIFKDIVMSHGVESDYKIESAATSNDEIWNGVGSPVYPQAAELLKRHGIACEGKRARKMVKSDYDNFDLLLGMDNANISEMKRIAGGDGDHKIHLLLEYTNNPHEISDPWYTRDFEKAYSEINQGCEALFIKLNS
>NZ_LT821227.1|WP_079536609.1|1338751_1339021_+|hypothetical-protein
MNVTHDEQLVFTHSDCPYYPCHSIAEGVKFNCIFCYCPLYALGPNCGGDFCYLDDGTKDCSKCTIMHEGAKGFERVREKFPELEDLAKA
>NZ_LT821227.1|WP_079536604.1|1337282_1338305_-|bile-acid:sodium-symporter-family-protein
MKTLEKISDFAGKYMAFIALAVTVIALIIPGPTHTILPTSWVNPLLGIVMFGMGMTLKLSDFKVVFIKPKAVITGIFSQFIIMPFLAWVLCLIFQLPTELAVGVILVGCCPGGTSSNVMTYLSKGDVALSVGMTACTTIMAPVVTPALVLLLAGQTINVSYVSMLMSIVQVVLVPIVLGFLINAVAPKVSEVFGKVLPLISVIAISLIIMAVVSANAAKIMTSGLLIIAVVMLHNVLGYALGYGVGRALHLSKAQVRTLSIEVGMQNSGLATSLALTHFASMPLAAVPGTVFSVWHNISGAVYANILAATAGKTSDAKQEGAEEENTNNQAADKKASAHA
>NZ_LT821227.1|WP_079536635.1|1348661_1349303_-|DNA-3-methyladenine-glycosylase-2-family-protein
MYFEYGETETSYLCSKDARLKDVIERIGHVDRNVDPDLFSSVVHHIIGQQISTKAQATIWLRIRNELGVVNAESILDAVPEQLQSLGLSFRKVVYIRDFSRKVHSGEFDLEAVKTMSDEDAIQALVALRGIGVWTAEMILLFCLQRPNILSYDDLAIQRGLRMVYHHRNITRKLFEKYRRRFSPYCSTASIYLWAVSGGAIPEMKDFKPKKSG
>NZ_LT821227.1|WP_079536637.1|1349637_1350030_-|riboflavin-kinase
MGNKKTENLGKVRGIVKHGRGDGVSLGFRTANLEVPRSSIPVDEGVYAAYVEVGNQCFRAAVSVGVSPLFKAETHANIEAHILDFDGNLYGNEITIEFVEFLRPMINFTSTQELISTVQHNINQARALPL
>NZ_LT821227.1|WP_079536640.1|1350732_1351503_-|transposase
MPRPLRCDSPLRVLNIGQKGHNGQVIFYYDEDREYYLECLQNACKKFGVVLLGYVLMSNHIHALFYGDIEKCASVFQSIGSTYVRWFNRKYGRTGTLWNSRFYSKPVQDEQQFLQTAAYIFNNPVKAGIVKRAENYRWSSFKDMDTKKFDEKAREILDSTLSIAYLKQYTHEAAEVKFDSDVQKQCEVIPNTTPSDLEVIDAVKRLVKSKNLGKIPMMSRSFLRKLVKELLKFGSNISQISRITTLTRHQVSVLAT
>NZ_LT821227.1|WP_079536643.1|1352240_1354844_-|FtsX-like-permease-family-protein
MSPLAKRHLRQLKNNWSRYLALFLLLVLFVSICSGFKAAVTSCQKIVGSVRDTYTVEDGRFTSNFELSNNVISRVEDKGVSLNELFSLTANSTFSSGNKEADFRVFKNRENVDKVAIHEGTLASESNEIALDVSFAHNNDINVGDVIAIQGLKFTVVGLISLPDAQMLFKDNSDMMGNSVSFGIGCVSKDGFASIKNSGATVSYTYSFVCDDRQLSDSKRFDLESEISDLLADEKVTLSSFIDSSMNNGINFATSDFEGDSSIVGVLMVLVIALLSFIFAVLNSSAIDSESAVIGTLLASGYRKSELLRHYMSPPVLIGIVAVILGNIVGYLFVIDYIAGLYYSSYSLPPFYANFDWGAFVETSIGPLLLLVFITFIGLVRKLRLTPLQFLRHDLKKHRKASKINLPENLPFTTRFRLRVILQNRGNFITLFFGITFASLLLIFGFCIIPTMDNYSDDLKTSMPAEHIYTLKSEVNLDGKQEEREAWSALMELRENVDMTRANEEDIANMARQYYISHSGHAELLGIETPEQFDTLKPSDLGFDDSVYGNMTISHLVDLIEKSSRIDISDENAIPVNSYELSKDALDQAEKIAVTTLKVPRRYSDSEEEVTVYGIQPNSKYWQNLSVNNLSENEIVCGPGLLDKCFVEKGVVFGANAEFTSDEYDLIPVDTWGGSTNTNIYMSIEQYRRIFGENEGYFNGYVSNEDLHIDKEYLARDMTTADMESVAIQMNQVMSRVVGIIVFLALVIYLIAMFLLTKIIVDKSARSISYMKIFGYRPKEISKLYISSITTTVVASLLISMPIIIFVVSWIMKLAMARYSGNLITMVPSIELIKVFLLGIFSYALVVILDLRHIRKVPMAMALKVQE
>NZ_LT821227.1|WP_079536645.1|1354855_1355560_-|ABC-transporter-ATP-binding-protein
MSEFLKVHALEKSYGDGESRTKVLRGISLSLDKGDFCVLLGPSGSGKSTFLNIVGGLELCDSGTISIEGREITKFNDKQLGEYRRETLGFIFQFYNLVPDLTIRENIEVTKHISNDPLSVDDLLHDLGLWEHRLKFPNQVSGGQQQRCAIGRALVKNPKLLLCDEPTGALDFSTSKEILGLLERVNKNYGTTILVVTHNEAISKMATRILRLHDGLLVENSFNENVAPASSLNW
>NZ_LT821227.1|WP_079536648.1|1356028_1357540_-|alanine:cation-symporter-family-protein
MDINEMLVQITGDIDTWMYTYVLLILLVAVGIYFSFKTRFVQIRFIGDMFRQVTEKKHVEGERSISSFQALMVSTASRVGTGNIAGVASAIAGVVGAGATGGAGAIFWMWAMALVGAASAFIESTCAQIWKVKDGEGAFRGGPAYYIEQAIGSRKFGVLFAILLILCFAFGFNGLQAFNACSSLEYYMPDYQTNGGAMIVGLILVLMTAAVIFGGAKRISVITSIVVPIMAFAYIAVAIWTTIIFADYIPQMFQAIFAAAFDWQAIFGGFTGSVIMLGIKRGLYSNEAGMGSAPNAAATASVSHPVKQGLVQSLSVYIDTLLICSCSAVMVCLFLVQDPETALQFKGIPLVQQAVQNSIGPIGIHFITFAIFAFAYSSLIGNYFYAESNFKFITKNKNALIVFRFLCLAAILYGAVNSFDLAWNLADIFMGLMAMMNLIVILIIGKWAILALKDYEKQKKEGKDPVFLASSIPGLPACDCWHEEHIPEIGEPVKEFFVDPLSK
>NZ_LT821227.1|WP_079536650.1|1358298_1360413_-|heavy-metal-translocating-P-type-ATPase
MFYRIAYDEPGRLRLRAGKWVFNDIQARGVACELLQIDDVSSVVVRVANGSVLVEYSKIRPQQTRQKILDYISSLDSECLPENPEDVTCDLAAINNAFIFSLARTVAIRYFKKIFLPYKLRLAWTLFNSLSYIKEGIRAFKKRKLTVEMLDATAITTALISGHVETAGQVMFLLGISDILADYTHARTRNALRQNLSICVEKVWLVQENEQEIEVPIESIQIGDKIRVRAGSVVPIDGFVVSGLAELNEATMTGESELVPKTLGNSVHAGTVVEEGLIVVQTTSKVGQSRIDSIVDLVDNSQSTKSLAQSKAEKLADSVVPLSLGLFLADLFLTRSVQRALSVLMVDYSCAIKLSTPIAVMSAMREATNHNIVAKGGKFLEAFAAADTIVFDKTGTLTNAKPEVHSVVSLGDYSEDDILRIAACLEEHYPHSMARAICRAADERNLQHKEELHNHVEYIVAHGIVSAVNGRRVVLGSAHFVFEDELVEKPQNLDSKIAEKNDAGSVVYMAIDGVLEGAIIVEDPIREEAFEVVSTLRDLGFARIVMLTGDSENCAKKVASELNLDDYYSQVLPEEKSSYVQRMKEEGHVVAFVGDGINDSPALACADVSIAMSDASDIARSVADVSVLDTSLKPLIELRKLSVALTNRVKSSYNFIIWFNTMLILLGLAGILTPEKAATLHNLSTIALSAKNTTPLLKPHNNKL
>NZ_LT821227.1|WP_079536653.1|1360422_1360752_-|hypothetical-protein
MKFVSHCKEAWCFVGGLAAAAVVAGLSRTECVRNGLVKATAQGMILKDNVSEAVQSIKDDAEDLTADAREEAKRITAEAEMKAEIEKRVREEVEKEFTKSSADSEKVSE
>NZ_LT821227.1|WP_079536655.1|1361670_1363248_-|phosphoglycerate-dehydrogenase
MPAKILVTEVIAQEGLDSLKSKGYEVDVRLNLDDASLKEIIGDYDALIVRSATSVNRALLRAGKKLKVVGRAGVTTDNIDIEAANDLDIIVCNAPTSNIVSAAEHTFALLLSCARKVPQANQSMHEAKWNREKFKGVELYAKTIALFGLGRVGGMVAERASAFGMRVFAYDPYCNPERATQLGVTLINDLDSILEQADFISIHLPVTKTTEGMFGPEEFSKMKTGVIFVNTSRPAIIDMKSLSDFVAARKIAACGVDVFDDEPCHDSPLHSLENAVLTPHISALTKEAQVRSGVQIADYVWAGLEGSLVPTALTATGSGAEMSRHVAPFIPAANMLGRMVSQIKGSVPRNVKVKMMGNLAELDPTALVASVLEGMLASKRAQCATMLEAKRYANRHGVNIECAKTDIADEYAAGIEIDADGIRIASTVFGTEKLPRITSILDYKIDVAPTKNALVFEYDDMPGVCGIIGTILGNHDINISTMQIATSEDYSTALVYVNVGEEIPDDIIDEFQDRINLKNLFRINL
>NZ_LT821227.1|WP_079536658.1|1363368_1364451_-|3-phosphoserine/phosphohydroxythreonine-transaminase
MTRVFNFSAGPANLPLSVLEEAQKDLVDYKGCGMSVMEMSHRSKDFASIIETTEADLRELLHMPDNYRVIFMQGGATAQFAAIPMNLMKNGKADYLQTGNWSKKALTEAKMYGDVNVVASSEDNNYTAIPDIKGLKFDKDADYVYICENETVYGCKFPELPDTGNIPLVSDVSSMFLSEPHDVSKYGLLYGGVQKNIGPAGLAIVIVRDDLVTEEVLPGTPSILNYKKNADAGSLMNTPNCWGIYMCGLTFKWLKQLGGLEKIKEINERKAKVLYDYLDQSKMFKAAVQKESRSLMNVPFVTGDADLDAKFVAESAAAGLKSLKGHRSVGGMRASIYNAMPEEGVQALVDFMEKFEKENA

Crispr_ID: NZ_LT821227_9

• CRISPR_ID: NZ_LT821227_9
• CRISPR_location: 1398312-1398400
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_9

Consensus_repeat	Method
GGAATTTATGTCTGGCACCAGTGCAAGAAG	CRISPRCasFinder

spacers of NZ_LT821227_9

>9.1|1398342|29|NZ_LT821227|CRISPRCasFinder
TCTGACGCTAAAGTCTGATCCCTGTTTTT

CRISPR arrays and Neighbor proteins around NZ_LT821227_9

CRISPR arrays

The CRISPR arrays of NZ_LT821227_9

>merge|NZ_LT821227|9|1398312-1398400|CRISPRCasFinder
GGAATTTATGTCTGGCACCAGTGCAAGAAGTCTGACGCTAAAGTCTGATCCCTGTTTTTGGAATTTATGTCTGGCACCAATGCAAGAAG

>NZ_LT821227|9|8|1398312-1398400|CRISPRCasFinder
GGAATTTATGTCTGGCACCAGTGCAAGAAG	TCTGACGCTAAAGTCTGATCCCTGTTTTT
GGAATTTATGTCTGGCACCAATGCAAGAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536698.1|1394122_1394467_-|AzlD-domain-containing-protein	unknown	unknown	gnl|CDD|377512
NZ_LT821227.1|WP_079536705.1|1398997_1399768_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079536696.1|1392857_1393772_+|NAD(P)H-hydrate-dehydratase	unknown	unknown	gnl|CDD|238576
NZ_LT821227.1|WP_079536689.1|1389937_1391506_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|235463
NZ_LT821227.1|WP_079536693.1|1392304_1392766_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|181403
NZ_LT821227.1|WP_079536983.1|1394466_1395135_-|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl|CDD|224215
NZ_LT821227.1|WP_147571566.1|1381081_1387264_-|hypothetical-protein	unknown	unknown	gnl|CDD|199834
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|237005
NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536703.1|1397596_1398112_+|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|376586
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|274014
NZ_LT821227.1|WP_079536691.1|1391493_1392282_-|triose-phosphate-isomerase	unknown	unknown	gnl|CDD|234589
NZ_LT821227.1|WP_079536700.1|1395505_1397332_-|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NZ_LT821227.1|WP_157887304.1|1400383_1400554_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536687.1|1389574_1389835_-|preprotein-translocase-subunit-SecG	unknown	unknown	gnl|CDD|235881
NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein	unknown	unknown	gnl|CDD|176102
NZ_LT821227.1|WP_079536708.1|1400706_1401888_+|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|225212
NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341239
NZ_LT821227.1|WP_157887305.1|1402536_1403520_-|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl|CDD|235511

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536698.1|1394122_1394467_-|AzlD-domain-containing-protein	gnl|CDD|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	1.45309e-05
NZ_LT821227.1|WP_079536705.1|1398997_1399768_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	1.31636e-09
NZ_LT821227.1|WP_079536696.1|1392857_1393772_+|NAD(P)H-hydrate-dehydratase	gnl|CDD|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	6.42514e-56
NZ_LT821227.1|WP_079536689.1|1389937_1391506_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl|CDD|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	gnl|CDD|237005	PRK11864, PRK11864, 3-methyl-2-oxobutanoate dehydrogenase subunit beta.	3.65937e-110
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	gnl|CDD|181403	PRK08367, porA, pyruvate ferredoxin oxidoreductase subunit alpha; Reviewed.	2.62764e-122
NZ_LT821227.1|WP_079536983.1|1394466_1395135_-|AzlC-family-ABC-transporter-permease	gnl|CDD|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	2.72932e-32
NZ_LT821227.1|WP_147571566.1|1381081_1387264_-|hypothetical-protein	gnl|CDD|199834	cd10276, BamB_YfgL, Beta-barrel assembly machinery (Bam) complex component B and related proteins. BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.	7.13911e-22
NZ_LT821227.1|WP_079536703.1|1397596_1398112_+|30S-ribosomal-protein-S20	gnl|CDD|376586	pfam01649, Ribosomal_S20p, Ribosomal protein S20. Bacterial ribosomal protein S20 interacts with 16S rRNA.	2.43375e-17
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	gnl|CDD|274014	TIGR02175, Pyruvate_synthase_subunit_PorC, 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins (H. pylori) used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes the gamma subunit. In Pyrococcus furious, enzymes active on pyruvate and 2-ketoisovalerate share a common gamma subunit.	1.03462e-47
NZ_LT821227.1|WP_079536691.1|1391493_1392282_-|triose-phosphate-isomerase	gnl|CDD|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	4.22079e-131
NZ_LT821227.1|WP_079536700.1|1395505_1397332_-|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LT821227.1|WP_079536708.1|1400706_1401888_+|MBL-fold-metallo-hydrolase	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	2.72977e-83
NZ_LT821227.1|WP_079536687.1|1389574_1389835_-|preprotein-translocase-subunit-SecG	gnl|CDD|235881	PRK06870, secG, preprotein translocase subunit SecG; Reviewed.	1.79703e-07
NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein	gnl|CDD|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.4584e-14
NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein	gnl|CDD|341239	cd05913, PaaK, Phenylacetate-CoA ligase (also known as PaaK). PaaK catalyzes the first step in the aromatic degradation pathway, by converting phenylacetic acid (PA) into phenylacetyl-CoA (PA-CoA). Phenylacetate-CoA ligase has been found in proteobacteria as well as gram positive prokaryotes. The enzyme is specifically induced after aerobic growth in a chemically defined medium containing PA or phenylalanine (Phe) as the sole carbon source. PaaKs are members of the adenylate-forming enzyme (AFE) family. However, sequence comparison reveals divergent features of PaaK with respect to the superfamily, including a novel N-terminal sequence.	1.08167e-141
NZ_LT821227.1|WP_157887305.1|1402536_1403520_-|DNA-polymerase-III-subunit-delta	gnl|CDD|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	2.38169e-29

Protein sequences

>NZ_LT821227.1|WP_079536703.1|1397596_1398112_+|30S-ribosomal-protein-S20
MANIKSQKKRIITNEKSRMRNRAIKSELKTATRKVKDAVAEGNGKEAFAAACAACRLMDKAVTKGVIKKNQAANRKSGIMKLANTVVTEEDRKAYEPKKGAAPEATGNKKAAAKQARKDEMKKAQKEKDKRRSAQKKQEEAAAKRKAKEEAEAAKAAAEAEAAEASEEAAE
>NZ_LT821227.1|WP_079536700.1|1395505_1397332_-|elongation-factor-4
MTIDQSHIRNFSIIAHIDHGKSTLSDRILEQTGTVAAREMEAQLLDQMDIERERGITIKSQAVRVNYTAEDGEEYQLNLIDTPGHVDFTYEVSRSLAACEGAVLVVDATQGVEAQTVANAMLAMNANLEVVPVINKIDLPSAEPDRVRAEIEDSLAIPADDAVLASGKTGQGITDLLESVVYNVPSPTGNPNASLRGLIFDSFFDPYRGVVALVKVEDGKLSKGDKIKMLATKTTAIVEEVGARHPAEEPLPSINTGEVGYVVTGLKDVNQVKVGDTITLIQNNDVEPLPGYREAKPMVFTGLFPIDSDQYEPLKEALEKVALNDPALVWEPETSRALGFGFRVGFLGLLHMEVIKERLEREFSLDLLATAPSVEYHVYRRGVTEGPGSEGEPLVITSPQDMPDAGEIERVEEPYLNAKILIPPDYVGAVMDLAVDRRGTFKTMNYLSSTTVELLWDIPLSELIMDFFDKLKSYTKGYASLDYDYDGYRKSDMVKLDILLAGEPIDALSFIVHKDKAYDRGKVLCEKLKEIIPRQLFEVPIQAAIGGRVLARQTVKARRKDVLAKCYGGDISRKRKLLEKQKQGKKRMKAIGNVEVPQEAFMAILKVN
>NZ_LT821227.1|WP_079536983.1|1394466_1395135_-|AzlC-family-ABC-transporter-permease
MLGYVAIGIPCGILSASMGLNWLQVLLFSIFFYSGAGQFMIPNMFLAGADLLSIFASVSFVNTRQTLYSAALAPFCERSRKRRMFWYMVTVTDETFGIAISKFKQGNWSVERAIFLNEFSHASWTISCVIGCLLGPVINIPLPIASFAMTSLFICLVVGSIKTKPTFVAAVAGVVGVIVFKSVGLTGPAIFLGAIFGVVVAYAFAQLQNRRAKVDNSEAGES
>NZ_LT821227.1|WP_079536698.1|1394122_1394467_-|AzlD-domain-containing-protein
MSWTTFGVLFLSVTVTIAACRVMPAFILKGKQISERMQLCLNLIAPAAFGALVANDIFTAGMFDAGIWPGCLPVLAAVVVFLVAYKTKSMIICCLAGIGIYAVLYAAATGGFAF
>NZ_LT821227.1|WP_079536696.1|1392857_1393772_+|NAD(P)H-hydrate-dehydratase
MELARYSNFLPQNNPHVHKYSRGRVAVIGGSGKYPGAVMLASKAVARAGAGYVTAFVPICIRTIFQSSLPEIVSVPIPNNTESFIGKNAFEFISLEKQHCVLYGPGVGSGKTQTKLLKKLVNADTPLVVDADMIEALASLEDINGAKSVYGRTTPLIITPHHGELKKWLRDNREDDYNKLDPSLIAFRVQGKLKAAEANNVVVVAKGEKTQVITSTSVLNPAGGTDTLATAGTGDVLAGTIAGLIAQSRPTSVSETANVCAAAVEAHALAGEIASKQFGRRGAMANNVCDCIGLAIDQLHGKEE
>NZ_LT821227.1|WP_079536693.1|1392304_1392766_-|hypothetical-protein
MDKAKRDLKSTSVIIIVLAIFDLIGAIASVALPNGAYSYETLVNITGMAPSLASTTVNSTVGVAILVFLLLVFVGLKGIIVSNGGKRSRLATAIVSLCTLAMCLQIAATCYALFMGTTDFMHSRLIVQVTVIVILILYNALTKKVISLRKTTV
>NZ_LT821227.1|WP_079536691.1|1391493_1392282_-|triose-phosphate-isomerase
MRKPIIAGNWKMNNTVAEGVVLAQEISNNFYRDYTEFVDVIICPPAVDLKAVKGVLEFDKRDIYVGAQNCYFEPSGAYTGEISVKMISDAGCDFCIVGHSERREIFGETNAMINDKVRALVEYQGKKMTPILCVGESLAVRESGDYIDYVTKQAEAALAGIDIFDADQLVIAYEPIWAIGTGRTATPEQAQEVCAAIRSCLANILGGAMAEKIRVLYGGSMNEGNVDSLLEQPDIDGGLIGGASLKASSFVNLVKAAVECQK
>NZ_LT821227.1|WP_079536689.1|1389937_1391506_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKVDKSKLNLPACLIIMDGFGLRDEKEGNAIALANTPNLDRLFLSCPHTQLAASGEPVGLPDGQIGNSEVGHLNIGAGRLVPQELTRINHACRDGSIAKNEVLVQAFDNCIKKNSRLHLLGLLSDGGVHSSIDHLFALIDAAVSHGVETIRVHAFLDGRDVAPTSGTKYVTETLEKFEQVRLEHDNVNIKFGSICGRFYAMDRDNRWERVNSAYRSVVLGENLSRELNPLEYVVHSYKEGITDEFVEPAAFCSKGIRKGDSCVFFNFRPDRAREITRAIALDEFCDFNREKVQDLFFVCLTQYDETFPLPVAFPKSFPENVLSDVVSDAGLKQIHIAETEKYAHVTFFFNGGVEEVKPGEDRILIPSPKVSTYDLKPEMSEPEVTESLVQAIENDSADFYIVNFANCDMVGHTGVLDAAIKAVEAVDDGVGKVTDAIEKKGGFALVTADHGNADQMIAEDGQPHTAHTTRLVPLILCDYTGKNREFTDESHVGALCDIAPTMLTLAGLSVPPEMTGSNLSA
>NZ_LT821227.1|WP_079536687.1|1389574_1389835_-|preprotein-translocase-subunit-SecG
MSPIAIILLVLLFLSGTGLVIFILMHSGKGTGISDAIASSMYSSQSGTSIIEKNLDRITIICAVVFIVTLILMMVFFPTGMIQSGN
>NZ_LT821227.1|WP_147571566.1|1381081_1387264_-|hypothetical-protein
MRAFLALSLVISLSPHLVFANDSDQNSSSSSQAALSQNSSTEGSDIDAGGATSVSSPVSESSSAEAQVEGGGTANAEGVSSDSEVAILNDTSEQDVNTSAIGNDAGEPESAADTATLTSGSELSSQAFVLIQSTKDYSTTYPQKYGTLKNGDVLWANMFDKVETEDYWGDPTTETKSVVNPGGWTYTWIASDTKGDETSVYTQELGHDQSLTVTSDMAGKYIICKVNAGGKDYFAPASTYDGSFNANYIPGSVLGAGQYELANVKLSSDAPSVGDTLTATSYISYSSQAPADANITYTWYSSSSQKSGFAIIEGQTGSSISVTDDLSGKYIKVEASAGVNTVSKTTTSKVKLAGEVELSAISIINIKDNTSVFTVGDTAKARAKEKGGAYGAFVDPSKLCFQWQSCDTKGGTYADIDGATNETLVLSDDLGGKYLKCLVSSKIGTSSLTNSTGALIASAGSINVTSVEMSPSSGKVEVGATITATAKAASGDVTNDSHVKWRWYKGTSKTASSCNTLIEGRTSSSITVDESLKGFYVVATADGGYGEKKPYYAAGPVSVAGQVELYDVQFEGSYETNGVRVGNTIKSKVRKKDGSSYSYLNNTDKVTYQWQYSDTNTSYDSSFKDIPDATSSSYTVEEAYVGKYLRVKVTSENTLYSTQKKSSYGSGYSAKDPLGPVTLKGQYKLAAIELADKNVLLQVGSKLTPRVLVPGSYAGSTKDVPADAELTMAWYESSDNGATWTEITDGIDTSDGSLTMSDPLVGKRLKVTASALDNTVEWVSSSVVGSQGEYDLLRVITNPAANDDSTQLVTGDSISATVQAKRADGSTTNGIDVTKNVDVEWFASDSSDGEFTKIEGLAGSSVTLPDSVSNKYIKVVVNSGNSSVEAQFKKAVLGKNSLAAAIQKLNDANVQLSVEYSPEGGNVNDTLKAVLLNLGYADVDVKVMEGGVAFKQTDPSATVGISDAHDDSNGTVTFLKIDPNNYSGFSIDQLRYADVVFKLTRGDEVDYYQPDRTVSVAWDESALQSLLDSAAEQIAIGFAEGDSAESVTANMTLPYRAGSNNKFEVSWSTSDKEAVWVSGYGWSDYTGKVTRTATDREVTLTATLKLIKDGPEGVSGYCGFNLVVKGDPEKVAAEKEALQQKVDTGFTYDKVKYAGSDLVANHEGLTDDLQMPRPSDLGVDGKYYKVEFSASTEDVVFNGYRGAVYQPMSGTSAAATKISVTVTDKSNSEISATKTLDYFIEPQDQAELEAELALMEQAKAGYTEALLDGQVASEVTENLHAFQKAYLKDDGTIAWSYSKQTSDSAGSGIVPVEIKGASETAGYRLFKSSKPNVVQHENLVVKQPVYNTRVKITSVLSSEKFARYAEKYPDNPTYAKLANQEVTATVVVKGSTGSDDPNAGKDLKVTAKVTGVSDMNADGTYTDIVVAPFSEITVDYDDSVTAETILEKIMIKAGCSDLVSNSLGLTSAKLPDGRTLAMEEVNGSWSWWEFYLNGVSQSSVGAAGYYVNDGDFVEFRYHKGDGTKKDNTDNIKSDPSAPRPDWQSSWPGYNNGGNASSNASTPVENAKEIWKFSYKDYSDSKHPNASEPLIVNDYIYLAVDGKLVKINKASGDVVGSADLAGSVGFTSRPVYSQGVVVVPLDTGRLQALTADNLTTVWVTDELSSAAQSNSTLTVSGDYVYFGTVDVDYTNKIFNNGHFVKVSLKNGAVAWSDVDENEGYYWNGALVKDGCVVVATSAGTVKAFNDKDGTLLSSVSLGQLVNSDCVAGPGGNIIVMSRDGKLNVLSLNNAALSVENAFDLGFSGSASTPVIVGNCVYVGGEIRGGSALAVVDFMTDNPHVTLVTSADGQSLLSGGVKGAPLVSTQSEGTFVYFTVNGADGYNKKTGNYEKGGGIYRYRVGDVEATLMFDPVGNNQYCDSPIICDTDGTLYYINDSGNLFCVGKAVKDDDNTNNSGDDTSGSTKSDPSVFPYYGYAQRAVIGASLIQSSKAASGEKKAADESVADKKGTSKKGSDLSGDSSQKKETPASTSNDVFVASVVAGSVLFLILLLAALRLLKKKNL
>NZ_LT821227.1|WP_079536705.1|1398997_1399768_-|transposase
MPRPLRCDSPLRVLNIGQKGHNGQVIFYYDEDREYYLECLQNACKKFGVVLLGYVLMSNHIHALFYGDIEKCASVFQSIGSTYVRWFNRKYGRTGTLWNSRFYSKPVQDEQQFLQTAAYIFNNPVKAGIVKRAENYRWSSFRDMDTKNFDEKAREILDSTLSIAYLKQYTHEAAEVTLDSDVQKQCEAIPNTTPSDLEVIDAVKRLVKSKNLGKIPTLSRSFLRKLVKELLKFGSNISQISRITTLTRHQVSVLAA
>NZ_LT821227.1|WP_157887304.1|1400383_1400554_-|hypothetical-protein
MRPTFDGDTAILVFLHWCQTSGTGARHESPVPDLNSKNKTVVGIAINSSLARVPDF
>NZ_LT821227.1|WP_079536708.1|1400706_1401888_+|MBL-fold-metallo-hydrolase
MKSTTRRSVKTSRNDFSPSPNINKEASFRCLKDRVNNQCVYDHSGFRSSKSYNKCAAITDNFSCGCTSKLFSLFAAVVIFVSILFLGGCASSAENIFSDASQSEGNAATQQSGDSTIKQNKEGEVNESTGSSPDFESKGELKVRFIDVGQGDCALVSFGEHHMLIDGGKPKASSTVYTILERLGISEIERIVASHPDADHCGGLAGALEIAKCDNFYCSTTESNTRTFDNIKKQVSRQGIGITVPKVGDNFKLGEATVTFIGPTSKFESDNNNSLILRIDYGNKSFLFTGDMEHESEASIIQSGENTKADVLKVSHHGSRTASGSRFLSKVRPEYAVISCGKNNDYGHPHKQTLNHLQKVGAKVLRTDELGDIVFTTDGNTLTVRTTKEGIED
>NZ_LT821227.1|WP_157887305.1|1402536_1403520_-|DNA-polymerase-III-subunit-delta
MTKSKQKKLDPIYLLIGDDEQKKSALLARMKDRCKEFGEMEINTDVFDGETHQPERAVSACLTLPFASDKRLVIIKDVDKYNAAELNVLADYATEPSDTSILLLLATKLAKNTRLYKRVIAISENAVIPCDSPKPREFEKYAIDVAKTKGVRLLDSGAKKLVELVGQDTTKITNELSKIIASHSSSRPIDQVEVESLVAASAEVKVWVLADAFAARNLTKVIELLPRVMGTTPSGVLYYCVARARELICAKECLKSGTSNINERIAKELGLPSSLSWRVKQHAAWSRQFSTEELKRAIKTSVEAEIEMKRGGDPVAVLTLWLAKTLG
>NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein
MAKKQIPNDQKYYDPEIECMPREDIEKMQLERLQEMVKFAYENAPYYKRSFDEAGVKPEDIKTLKDIAKFPFIDKKTERETQGIGSFFGELCAVDEEDVIFMATSSGSTGVPTVSPFTQEDFDLWQDTEARLFWQAGMRPKDKYVHALNFALYVGGPDVIGAQNLGATAIWVGAVPSDRLLFVLKQYQPTVIWTSPSYAWQLGNKAIAKGFDPKKDFSIHTIIVAGEPGGSIKSTREAIENLWGAKVVDFFGLSDIYGACAAMCEAKDGLHIVEDQILVETVDPATGEVLEPDERGELVYTTLMKKARPMIRFRTGDIGYVSTDKCSCGRTLARIHIQGRKDEMFIVGAVNVFPTDIEYVVRKEEGLTGEYSIRVYNENYSTRYEVSVERAQGSSESFDAVSKRVENALKTHTGVRPAKVLVYDAGALGTESEHKASRFIDERGKGDK
>NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein
MAKNFAVSGQHYLFNVQAFAHTILTMGGDVYDYAYRDRSTAGIIDDVKNGTSELGVIMQTERSKNEINAALAEAGLKFVPIKESKPMVALSASHPLSNAKSLRLEELEAWPYLYFEQRPDSPVSFCEEALAQIPRNKTIACNDRASLSELAVAVNGYTITSGILVGITDGGSLATVPLETDETLSLGYIVKENSSFSPAAERFIEELTKELNLYAK
>NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein
MIEIIWHGRGGQGAFTAARLLGAAASISGENSSLAFPTFGPERRGAPMRAFTKIDRRPIGNRSEVKQADYVVYLDETLLAEGWDKELKDTVKNLNADMITSPVVLVNSKKHFNDPRIKSIDASGIATDILGRNIPNTVFLGLICAMCDALSIEDAREAIRHYMPEKLHEKNLAIIDKVANAKEALNKKGGDNETIVASNHGSNSSESRIAINRQNSPEGQTTKIAFKKSEIVNGLSRPNCVIPKLHSEAVSPKEFAHNTCWQAGWLTTKNAGWRTFRPKIDQEKCTGCLKCYMDCPDGCIFKMQESRTVGIDLDFCKGCAMCAEACKFDAIEMIAERSAE
>NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase
MRHFLSGDEALAEGVRLCRPKVISAYPITPQTVVVERLSEMVEAKTLDAKYMHVESEHSALSAAMGASATGVRTFTATSSQGLLYMAEVLTYAAGGRFPIVMMNANRSTALPWNIYGDQRDSLALLDHGWIQAYAENNQEALDLTLMAYRIAEDKDVSTPFMINLDGFALTHTYETVDIPTQEEADSYLPQYSTANRFDFKNPVNMAYSAGPATNKLFKFAEHDDMVKSLDVISNAEKEFEKIFGRHYSGPVETYRCEDAEFVLVTLGSIAGLARTVVDDLREKGTKAGLLKIRYMRPFPEKQIANALKFAKCFAVLEKDISFGFEGTVFTNVKSAMHNNRADVPGINFIGGLGGDDIAENDIEAIFKECEKCARAGVSQTVYWLSIDEGQVK
>NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase
MAVNARNISDNELFFGHKACAGCGGALALRHALKVLGPDTTIALPAGCMSAVGFNFPQLCFANNAMITPFAATAAVASGIAAGLEMQGIDTATHPVIGFAGDGGTADIGIQALSGAIDRNEDIIYFCYDNEAYMNTGIQKSGLTPLCASTTTTPAGKNAHGALTQKKNIFEIVAAHGISYAATSSVGYLSDYIKKVEKAQSIRGTKFIHVIAPCPTGWGHAESATAKFAKDVVDCGLWYLAEYEGEQVCGVPGGKFKINKAPKEFSSIEHYLRAQKRFSRIDDDDIRTITASRDSKWKQIKRDWE
>NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein
MEAEPESIAVLVANYVWHQCLRLNLCLTPSQMRITTRRLDLCLALMIHDWHQCFGTKGKGARKVLLFFSQIMSGTSDLCLTPSQMRITTRRLDLCLALMIHDWHQCFMSDTNDPCLEPMEAEPENITVLVANYVWHQCFMSDTNDPCLEPMEKGPSDLSLAPVFYVWHQ

Crispr_ID: NZ_LT821227_10

• CRISPR_ID: NZ_LT821227_10
• CRISPR_location: 1414861-1414950
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_10

Consensus_repeat	Method
AATGGTGCCAGACATGAATTGCG	CRISPRCasFinder

spacers of NZ_LT821227_10

>10.1|1414884|44|NZ_LT821227|CRISPRCasFinder
GGTGCCAGACATGAATTGCGATGGATCTTTAATCAGCGGTTTAC

CRISPR arrays and Neighbor proteins around NZ_LT821227_10

CRISPR arrays

The CRISPR arrays of NZ_LT821227_10

>merge|NZ_LT821227|10|1414861-1414950|CRISPRCasFinder
AATGGTGCCAGACATGTTTCAATGGTGCCAGACATGAATTGCGATGGATCTTTAATCAGCGGTTTACATTGGTGTCAGACATAAAGTCGA

>NZ_LT821227|10|9|1414861-1414950|CRISPRCasFinder
AATGGTGCCAGACATGTTTCAAT	GGTGCCAGACATGAATTGCGATGGATCTTTAATCAGCGGTTTAC
ATTGGTGTCAGACATAAAGTCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	unknown	unknown	gnl|CDD|238233
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	unknown	unknown	gnl|CDD|234719
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|237005
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|181403
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	unknown	unknown	gnl|CDD|377623
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|234744
NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	unknown	unknown	gnl|CDD|223728
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|131996
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl|CDD|379113
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	unknown	unknown	gnl|CDD|239264
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239171
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	unknown	unknown	gnl|CDD|376858
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl|CDD|225212
NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341239
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl|CDD|213597
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|274014
NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein	unknown	unknown	gnl|CDD|176102
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	gnl|CDD|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	4.00741e-39
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.31315e-09
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	4.43116e-96
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	gnl|CDD|237005	PRK11864, PRK11864, 3-methyl-2-oxobutanoate dehydrogenase subunit beta.	3.65937e-110
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	gnl|CDD|181403	PRK08367, porA, pyruvate ferredoxin oxidoreductase subunit alpha; Reviewed.	2.62764e-122
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	gnl|CDD|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	2.19199e-31
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	4.46812e-08
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.4286e-31
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|131996	TIGR02951, anaerobic_dimethyl_sulfoxide_reductase_subunit_B, DMSO reductase, iron-sulfur subunit. This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.	9.25921e-55
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	gnl|CDD|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	3.07888e-81
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.62298e-18
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|239171	cd02770, MopB_DmsA-EC, This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a predicted N-terminal iron-sulfur [4Fe-4S] cluster binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	gnl|CDD|376858	pfam02613, Nitrate_red_del, Nitrate reductase delta subunit. This family is the delta subunit of the nitrate reductase enzyme, The delta subunit is not part of the nitrate reductase enzyme but is most likely needed for assembly of the multi-subunit enzyme complex. In the absence of the delta subunit the core alpha beta enzyme complex is unstable. The delta subunit is essential for enzyme activity in vivo and in vitro. The nitrate reductase enzyme, EC:1.7.99.4 catalyze the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen. This family also now contains the family TorD, a family of cytoplasmic chaperone proteins; like many prokaryotic molybdoenzymes, the TMAO reductase (TorA) of Escherichia coli requires the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make it competent to receive the cofactor.	9.22114e-22
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.28417e-49
NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein	gnl|CDD|341239	cd05913, PaaK, Phenylacetate-CoA ligase (also known as PaaK). PaaK catalyzes the first step in the aromatic degradation pathway, by converting phenylacetic acid (PA) into phenylacetyl-CoA (PA-CoA). Phenylacetate-CoA ligase has been found in proteobacteria as well as gram positive prokaryotes. The enzyme is specifically induced after aerobic growth in a chemically defined medium containing PA or phenylalanine (Phe) as the sole carbon source. PaaKs are members of the adenylate-forming enzyme (AFE) family. However, sequence comparison reveals divergent features of PaaK with respect to the superfamily, including a novel N-terminal sequence.	1.08167e-141
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	gnl|CDD|213597	TIGR01259, ComE_operon_protein_1, comEA protein. This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation].	8.70833e-29
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	gnl|CDD|274014	TIGR02175, Pyruvate_synthase_subunit_PorC, 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins (H. pylori) used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes the gamma subunit. In Pyrococcus furious, enzymes active on pyruvate and 2-ketoisovalerate share a common gamma subunit.	1.03462e-47
NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein	gnl|CDD|176102	cd05466, PBP2_LTTR_substrate, The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily. This model and hierarchy represent the the substrate-binding domain of the LysR-type transcriptional regulators that form the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, oxidative stress responses, nodule formation of nitrogen-fixing bacteria, synthesis of virulence factors, toxin production, attachment and secretion, to name a few. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.4584e-14
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	3.87954e-146

Protein sequences

>NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein
MKNGKNKDKEFVGEVGKPLESASEKAEIGFGMVLLAVFIGFVIGLFVWAVFWASSALTQLLWVDSNNLISGLLINANIPTWWLPLAFCVSGGLIIGMWTSRVGGEPELLETVMEKVKTTGGYSLKKPGASVVGFLLPIVCGGSIGPEAGLTGIIAAACTRIGTSLKAAGIRVKLLTDTTLSAALSAIFASPFAGVVTTAEDCMNDFDPSNFQFHRRAKLVLYTASAIGATLGIALFTSIFGTESGIPRFGGVTPGINKLWWAIPCVISAYAAILIFHGSSFAFKKLGEKMGERQVLKPVIAGLVLGILAIPLPYLLFSGESQSFELMEMWTVVPGSLLIATGLLKCAMTPLCINFGWKGGHFFPIIFAGIALGYGVASIGGFNDMFCVAITTATLVAGIQRKPLMAIGTLLLCFPVESFPWFGIACLIGAYLPVPTKLLAKQAKQ
>NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein
MKIVVLSASPREGGNTSIMVDAFKEGAEIAGNTVEVIDVASKNIAPCRACQYCFEHEGQCAQEDDMTAIRKTLKEADMLVLASPIYWFDVSAQLKLAIDRLYAFGGTGFNFSKVAMLLDSGSDGVYEAATAAFKGMCSYLKWENMGIITIPGMVNKGDMANNPKLDDVRKFGASLK
>NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC
MDKVKAFFKRKDVEVSLKRYGVDALSAMAQGLFCTLLVGTILDTIGTQFGIAFLTTSLIDIAGTGYTIGKFASAMVGPAMAVAIGYALNAPAMVLFSLIPVGYATNVMGGAGGPLAVYVVAIVAAEFGKLVSKETKVDILVTPIVTILVGVGVAFFIAAPIGGGAMVVGTLIKWATTQEPLIMGVIVSVVVGIALTLPISSAAICAALSLTGLAGGAALAGCCANMVGFAVISFKENGWGGVVSQGIGTSMLQMGNIVRNPRIWIPAIAASAITGPLSTCVFKLEMNGAAVSSGMGTCGLVGPIGVWTGWTNPSAEALMDGAAAIVPTTFDWIGLVLISVVLPALLAWAFGVACRKLGWIKDGDMKLS
>NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein
MVKNLNNIAQAGIIAAIYAAATLVCNLVFPAISWGPVQIRLSEALCVVAVLYPSARAGLPIGCAIANLFNIVIAGTGALGFLDVVFGSLATLLGAILCWKLREKPMLAIFMFVITNAVIVPAYLPILCEWTGFYTIPFTDVALDGYYGWMWLFGFVSITISESLTLYVLGLPILHALKKANEK
>NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein
MEAEPESIAVLVANYVWHQCLRLNLCLTPSQMRITTRRLDLCLALMIHDWHQCFGTKGKGARKVLLFFSQIMSGTSDLCLTPSQMRITTRRLDLCLALMIHDWHQCFMSDTNDPCLEPMEAEPENITVLVANYVWHQCFMSDTNDPCLEPMEKGPSDLSLAPVFYVWHQ
>NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase
MAVNARNISDNELFFGHKACAGCGGALALRHALKVLGPDTTIALPAGCMSAVGFNFPQLCFANNAMITPFAATAAVASGIAAGLEMQGIDTATHPVIGFAGDGGTADIGIQALSGAIDRNEDIIYFCYDNEAYMNTGIQKSGLTPLCASTTTTPAGKNAHGALTQKKNIFEIVAAHGISYAATSSVGYLSDYIKKVEKAQSIRGTKFIHVIAPCPTGWGHAESATAKFAKDVVDCGLWYLAEYEGEQVCGVPGGKFKINKAPKEFSSIEHYLRAQKRFSRIDDDDIRTITASRDSKWKQIKRDWE
>NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase
MRHFLSGDEALAEGVRLCRPKVISAYPITPQTVVVERLSEMVEAKTLDAKYMHVESEHSALSAAMGASATGVRTFTATSSQGLLYMAEVLTYAAGGRFPIVMMNANRSTALPWNIYGDQRDSLALLDHGWIQAYAENNQEALDLTLMAYRIAEDKDVSTPFMINLDGFALTHTYETVDIPTQEEADSYLPQYSTANRFDFKNPVNMAYSAGPATNKLFKFAEHDDMVKSLDVISNAEKEFEKIFGRHYSGPVETYRCEDAEFVLVTLGSIAGLARTVVDDLREKGTKAGLLKIRYMRPFPEKQIANALKFAKCFAVLEKDISFGFEGTVFTNVKSAMHNNRADVPGINFIGGLGGDDIAENDIEAIFKECEKCARAGVSQTVYWLSIDEGQVK
>NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein
MIEIIWHGRGGQGAFTAARLLGAAASISGENSSLAFPTFGPERRGAPMRAFTKIDRRPIGNRSEVKQADYVVYLDETLLAEGWDKELKDTVKNLNADMITSPVVLVNSKKHFNDPRIKSIDASGIATDILGRNIPNTVFLGLICAMCDALSIEDAREAIRHYMPEKLHEKNLAIIDKVANAKEALNKKGGDNETIVASNHGSNSSESRIAINRQNSPEGQTTKIAFKKSEIVNGLSRPNCVIPKLHSEAVSPKEFAHNTCWQAGWLTTKNAGWRTFRPKIDQEKCTGCLKCYMDCPDGCIFKMQESRTVGIDLDFCKGCAMCAEACKFDAIEMIAERSAE
>NZ_LT821227.1|WP_079536717.1|1404940_1405591_+|LysR-family-transcriptional-regulator-substrate-binding-protein
MAKNFAVSGQHYLFNVQAFAHTILTMGGDVYDYAYRDRSTAGIIDDVKNGTSELGVIMQTERSKNEINAALAEAGLKFVPIKESKPMVALSASHPLSNAKSLRLEELEAWPYLYFEQRPDSPVSFCEEALAQIPRNKTIACNDRASLSELAVAVNGYTITSGILVGITDGGSLATVPLETDETLSLGYIVKENSSFSPAAERFIEELTKELNLYAK
>NZ_LT821227.1|WP_079536715.1|1403592_1404939_+|AMP-binding-protein
MAKKQIPNDQKYYDPEIECMPREDIEKMQLERLQEMVKFAYENAPYYKRSFDEAGVKPEDIKTLKDIAKFPFIDKKTERETQGIGSFFGELCAVDEEDVIFMATSSGSTGVPTVSPFTQEDFDLWQDTEARLFWQAGMRPKDKYVHALNFALYVGGPDVIGAQNLGATAIWVGAVPSDRLLFVLKQYQPTVIWTSPSYAWQLGNKAIAKGFDPKKDFSIHTIIVAGEPGGSIKSTREAIENLWGAKVVDFFGLSDIYGACAAMCEAKDGLHIVEDQILVETVDPATGEVLEPDERGELVYTTLMKKARPMIRFRTGDIGYVSTDKCSCGRTLARIHIQGRKDEMFIVGAVNVFPTDIEYVVRKEEGLTGEYSIRVYNENYSTRYEVSVERAQGSSESFDAVSKRVENALKTHTGVRPAKVLVYDAGALGTESEHKASRFIDERGKGDK
>NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MKIRKKKFGSIHGAGHDFAISTGEQGANFDVVIDDKTPRKPSMPFLLPCSLILWGSCLLSFLGTRSFDDSMKNTLLSVFAFGLLISLFACVHKQRRWLFLLLSFLMLGATLGVYKNVSLESNAIIALNSSVAEIDAQVLEDSTTGEFGNQTILSLNSKDFRDLRVLAYLDKNTCVLVGEKLKVKGTFKSLKPESKDFNFNRSVCSILKVSKAETVSINPVLSAVVNMRRDSIRNFETFGGQCGGLLQALVCGYKNTIEDDGTYEEFKVCGLAHTVAVSGAHLAIVVSFFLLLLKKFKVSHRASSFSSVAIVLCYLLFSGIPISAVRSAIMVVLCLIAGVQERRADSLNALSLCIILFIVADASTCTSVSLYLSSASTFGIIVFARLFSSWADCRNKVANGIIIQPIALTMAANLMTLPFSAAIFSQISTISVIANMIATPLFSAACVFGLLTALISIFFPAIASFCCFGASVVAFPLYECVEILGRIPFACIPLDFDVVLSILFSALLALSLIVVWPKLSRRLACASLSVCIMLPFAFVFVSFIVPQNRIAFIDVGQGDAILIQSNGCNFLVDTGNNETKLRTGLAKLGVFSLDGVLITHHDDDHMGCLEVLRSYESIGAVNSAADAKTCACEGCNRLRSAATEATGKELCGLTVGDCVRAGNFSCKVVWPMEFSNEGGNEDSVCLKVSCNANSDSEAEFCALLTGDAEKEPLRQLLQQENLGTIDIFKIGHHGSKISVDDALLDELEPSVALISVGKGNRYGHPSSEALGLLQKHDVRVFCTDELGTIIVTPKFPTGFSVSTHG
>NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein
MPFQEFASNFKEDEKEKNQKPVYMVGIALLLIVAIAYFAFNVFTTGENSGFEVESVNSKDDVVDSKKIFVHVAGEVNNPGLQELDADARVSQAIELAGGATENADLNSVNLAKKCEDGEQIIIPAKVEPEVDADGAADETLSGSAAKRSSGASTLQGSGGASGAGKVNINTADASLLQTISGIGPSKAQKIIEYRKQNGSFKSVDDLTNVSGIGVKTLESIRSQICV
>NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI
MAADTFQRVVLVHYHEIGLKGHNRGRFEQKLVDNIKALTCDFPVSACHRISGRIVVFLKEGTTHDEQVRAQEFIATIPGIQRVSAGFKCLAEYDTMKELAVEALADAGEFQTFKVQARRNHTNFEPDSMVLNREIGEVLCNAFPEKKVKMKEPDVTVNVEVIENQCFVCARSIAGVGGLPVGTSGKVICLLSSGIDSPVAAWKIAKRGATCIGVHFSGRPQTGDESEYLVDDIARVLAKRGCMHQYFVCPIGDYQRKIALSCTPKLRVVLYRRLMFKVANALAEQCGAKAIVTGESLGQVASQTIENMIATSDASEKMVLRPLIGFDKLEIIDEAIRLGTFEISSQDASDCCTLFMPKMPETHAHLDEVKKEEEFFDPSWIDEIVASAELHRV
>NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega
MSVVEPKIHELLNRSENDRFLLCSMASKRAHDINDMMRGQRNRAVSTETAKEIAQASTVKPLSMAFNEIYRGEVSYDPQTIDAIHH
>NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase
MENEYEKLVIISSPSGGGKGTLIKKLLDDVDGVWLSVSATSRQPREGETNGKSYYFMSRDEFKESIEQNGFLEWAEYSGNLYGTPRKYIHDHLDNGDVVLLEIEVQGASDVMKKCPGCHSVFIMPPSLEILESRLRGRNTDSEESIRKRMQAAEFELECAEQYEKIIVNDDLDVAFKELKEYINRVAD
>NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMAKRAENYKWSSFKDLDSEKIDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDEKEFEVIPNSTPSDMLVIDAVKRIVKEKNLGKISALSRSLLRKLVKSLLKLGSNINQISRVTGLTRHQVGILAT
>NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein
MARGFFIDETKCTGCKACVVTCKDKRNLDAGFNLRFVNSQVWGSFPHVRMSYHSRSCNNCKNPACVENCPSGAMSRDNELGVVKVDLDVCIGCGKCAKACPFGAPTIDSDKKKSMKCDFCFDLTKDGQNPACMDVCNSRALEFGDLDELQRAHPDAKGVEGDTRPNTLVLFK
>NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase
MNLEETLKGRDFSRRTFLKGLAVLSAATMLDGCTNKLSNVVEEDAFKKAEEATGEAVWKNAPCWHNCGGTCCLKAQVKGDTIVRLKTDDSHPDSYDYPQQRACVRGLSERLQIVGKERLKYPMKRKHFDPEGKKGKDMRGRDTWERISWDEALDIVASQLKKAKQNYGNKSIYLLDGGEMKRTLALYGGYVAKSGSRSKGCWNKAMEPICGVTAKSHCLNDRMDLMNAKLIILWGCNPAQSSMGMPLLNLRRAKEAGAKIICIDPMFTRTAAVLADEYYPIRPATDTTLLLALSYVIIQKDKEAGGSIIDWDFLNRCTIGFDADHMPEGANVEENYMDYVLGTYDNEPKTPEWASKICGTPVEDINKIAEMIIKNKPTTCLFSWNSARVEKAQHVCLAQMALGSLTGNMGIKGGAFSCSSQESSTNGGPNLIKKGKDRIEEIKNPLSKPKLCTNHHWQDIVSGTWRDGKNGLKPLDIHVIYHSHSATLNQTNNVNKGIEAHHKVDFVVTNHYTFTPECQYSDVVLPVTTPWEKEGEVLQGNREAIIWTEKVIEPYFESKDDAWIAEEIAKRLGVDAYQANPVNNKQRCYNIIAGTTVVKENGKDYEKLVSVTEDDLKELGVKGKPQYGRVPILELKKAGIYQVERHLGDNYGYIANKKLRQNPEANPIKTESGKIELYCKALKKAVDKAGWNKGYAYAKYVPPTEGYEATFKDFENGVKGEYPYQVLGIHDLRGTHTVFNQVNYLREAFPYELEVNPIDAKEKGFKEGEVIEIFNSRGKILRKLHITERVMPGVIVIHEGVWVDMKDGRCIAGSPNVLTGDFPSGPDVESWNACIADMRKSSVSLEEDWKVDLAVKLDG
>NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein
MDNDKTDIFNFLQEKEEFYSFMSMVFMDSPTNAFCTTLWGMLNEDYFPLADNNIELHALCLSLREKLRETNLEEFTQALSQEYYNLFFDPCGINVSPWQSSYTNKEQLLFQETDGQAKAMYRRYGYKVEDNHLPGDHIAIELDFLSKLSSRELKNIDSVIQGGNKQLLSDIQNFICKHILSWIDEFIDSLKDNASVYYLLFASMVKIVCEEDKAFMPNL
>NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein
MFIQRSKRYFLTLLILTVFFALSLAGCASNNSTWSNNAEDEVKQQLTEMPNFESTDLDGNTITGDVFSNKKFTVVNFWGTYCSPCISEMQDLAEWSKGMEPDIQLIGVVCDVDSKGSSSFDTAVEICNSKGVKFTNVLANDSLAPAIQTLVGIPTTYIVDSNRQVVAGPIVGAQVDAYKQALQDCLAK

Crispr_ID: NZ_LT821227_11

• CRISPR_ID: NZ_LT821227_11
• CRISPR_location: 1419485-1419566
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NZ_LT821227_11

Consensus_repeat	Method
TCACGACACAAATTCATGTCTGACAC	CRISPRCasFinder

spacers of NZ_LT821227_11

>11.1|1419511|30|NZ_LT821227|CRISPRCasFinder
TAATGCGTGATGACTGACCCCAGTGTTATT

CRISPR arrays and Neighbor proteins around NZ_LT821227_11

CRISPR arrays

The CRISPR arrays of NZ_LT821227_11

>merge|NZ_LT821227|11|1419485-1419566|CRISPRCasFinder
TCACGACACAAATTCATGTCTGACACTAATGCGTGATGACTGACCCCAGTGTTATTTCACGACACAAATTCATGTCTGGCAC

>NZ_LT821227|11|10|1419485-1419566|CRISPRCasFinder
TCACGACACAAATTCATGTCTGACAC	TAATGCGTGATGACTGACCCCAGTGTTATT
TCACGACACAAATTCATGTCTGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	unknown	unknown	gnl|CDD|238233
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|131996
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|237005
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	unknown	unknown	gnl|CDD|181403
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	unknown	unknown	gnl|CDD|377623
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|234744
NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	unknown	unknown	gnl|CDD|223728
NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|274004
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl|CDD|379113
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	unknown	unknown	gnl|CDD|239264
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239171
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	unknown	unknown	gnl|CDD|376858
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl|CDD|225212
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	unknown	unknown	gnl|CDD|234719
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl|CDD|213597
NZ_LT821227.1|WP_079536985.1|1429960_1430113_+|thioredoxin	unknown	unknown	unknown
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	unknown	unknown	gnl|CDD|274014
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	gnl|CDD|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	4.00741e-39
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.31315e-09
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|131996	TIGR02951, anaerobic_dimethyl_sulfoxide_reductase_subunit_B, DMSO reductase, iron-sulfur subunit. This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.	9.25921e-55
NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase	gnl|CDD|237005	PRK11864, PRK11864, 3-methyl-2-oxobutanoate dehydrogenase subunit beta.	3.65937e-110
NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase	gnl|CDD|181403	PRK08367, porA, pyruvate ferredoxin oxidoreductase subunit alpha; Reviewed.	2.62764e-122
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	gnl|CDD|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	2.19199e-31
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.4286e-31
NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein	gnl|CDD|274004	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family. Most members of this family are the NapH protein, found next to NapG,in operons that encode the periplasmic nitrate reductase. Some species with this reductase lack NapC but accomplish electron transfer to NapAB in some other manner, likely to involve NapH, NapG, and/or some other protein. A few members of this protein are designated MauN and are found in methylamine utilization operons in species that appear to lack a periplasmic nitrate reductase.	2.98168e-23
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	gnl|CDD|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	3.07888e-81
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.62298e-18
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|239171	cd02770, MopB_DmsA-EC, This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a predicted N-terminal iron-sulfur [4Fe-4S] cluster binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	gnl|CDD|376858	pfam02613, Nitrate_red_del, Nitrate reductase delta subunit. This family is the delta subunit of the nitrate reductase enzyme, The delta subunit is not part of the nitrate reductase enzyme but is most likely needed for assembly of the multi-subunit enzyme complex. In the absence of the delta subunit the core alpha beta enzyme complex is unstable. The delta subunit is essential for enzyme activity in vivo and in vitro. The nitrate reductase enzyme, EC:1.7.99.4 catalyze the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen. This family also now contains the family TorD, a family of cytoplasmic chaperone proteins; like many prokaryotic molybdoenzymes, the TMAO reductase (TorA) of Escherichia coli requires the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make it competent to receive the cofactor.	9.22114e-22
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.28417e-49
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	4.43116e-96
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	gnl|CDD|213597	TIGR01259, ComE_operon_protein_1, comEA protein. This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation].	8.70833e-29
NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein	gnl|CDD|274014	TIGR02175, Pyruvate_synthase_subunit_PorC, 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family. A number of anaerobic and microaerophilic species lack pyruvate dehydrogenase and have instead a four subunit, oxygen-sensitive pyruvate oxidoreductase, with either ferredoxins or flavodoxins (H. pylori) used as the acceptor. Several related four-subunit enzymes may exist in the same species. This model describes the gamma subunit. In Pyrococcus furious, enzymes active on pyruvate and 2-ketoisovalerate share a common gamma subunit.	1.03462e-47
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	3.87954e-146
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	4.46812e-08

Protein sequences

>NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein
MPFQEFASNFKEDEKEKNQKPVYMVGIALLLIVAIAYFAFNVFTTGENSGFEVESVNSKDDVVDSKKIFVHVAGEVNNPGLQELDADARVSQAIELAGGATENADLNSVNLAKKCEDGEQIIIPAKVEPEVDADGAADETLSGSAAKRSSGASTLQGSGGASGAGKVNINTADASLLQTISGIGPSKAQKIIEYRKQNGSFKSVDDLTNVSGIGVKTLESIRSQICV
>NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MKIRKKKFGSIHGAGHDFAISTGEQGANFDVVIDDKTPRKPSMPFLLPCSLILWGSCLLSFLGTRSFDDSMKNTLLSVFAFGLLISLFACVHKQRRWLFLLLSFLMLGATLGVYKNVSLESNAIIALNSSVAEIDAQVLEDSTTGEFGNQTILSLNSKDFRDLRVLAYLDKNTCVLVGEKLKVKGTFKSLKPESKDFNFNRSVCSILKVSKAETVSINPVLSAVVNMRRDSIRNFETFGGQCGGLLQALVCGYKNTIEDDGTYEEFKVCGLAHTVAVSGAHLAIVVSFFLLLLKKFKVSHRASSFSSVAIVLCYLLFSGIPISAVRSAIMVVLCLIAGVQERRADSLNALSLCIILFIVADASTCTSVSLYLSSASTFGIIVFARLFSSWADCRNKVANGIIIQPIALTMAANLMTLPFSAAIFSQISTISVIANMIATPLFSAACVFGLLTALISIFFPAIASFCCFGASVVAFPLYECVEILGRIPFACIPLDFDVVLSILFSALLALSLIVVWPKLSRRLACASLSVCIMLPFAFVFVSFIVPQNRIAFIDVGQGDAILIQSNGCNFLVDTGNNETKLRTGLAKLGVFSLDGVLITHHDDDHMGCLEVLRSYESIGAVNSAADAKTCACEGCNRLRSAATEATGKELCGLTVGDCVRAGNFSCKVVWPMEFSNEGGNEDSVCLKVSCNANSDSEAEFCALLTGDAEKEPLRQLLQQENLGTIDIFKIGHHGSKISVDDALLDELEPSVALISVGKGNRYGHPSSEALGLLQKHDVRVFCTDELGTIIVTPKFPTGFSVSTHG
>NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein
MKNGKNKDKEFVGEVGKPLESASEKAEIGFGMVLLAVFIGFVIGLFVWAVFWASSALTQLLWVDSNNLISGLLINANIPTWWLPLAFCVSGGLIIGMWTSRVGGEPELLETVMEKVKTTGGYSLKKPGASVVGFLLPIVCGGSIGPEAGLTGIIAAACTRIGTSLKAAGIRVKLLTDTTLSAALSAIFASPFAGVVTTAEDCMNDFDPSNFQFHRRAKLVLYTASAIGATLGIALFTSIFGTESGIPRFGGVTPGINKLWWAIPCVISAYAAILIFHGSSFAFKKLGEKMGERQVLKPVIAGLVLGILAIPLPYLLFSGESQSFELMEMWTVVPGSLLIATGLLKCAMTPLCINFGWKGGHFFPIIFAGIALGYGVASIGGFNDMFCVAITTATLVAGIQRKPLMAIGTLLLCFPVESFPWFGIACLIGAYLPVPTKLLAKQAKQ
>NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein
MKIVVLSASPREGGNTSIMVDAFKEGAEIAGNTVEVIDVASKNIAPCRACQYCFEHEGQCAQEDDMTAIRKTLKEADMLVLASPIYWFDVSAQLKLAIDRLYAFGGTGFNFSKVAMLLDSGSDGVYEAATAAFKGMCSYLKWENMGIITIPGMVNKGDMANNPKLDDVRKFGASLK
>NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC
MDKVKAFFKRKDVEVSLKRYGVDALSAMAQGLFCTLLVGTILDTIGTQFGIAFLTTSLIDIAGTGYTIGKFASAMVGPAMAVAIGYALNAPAMVLFSLIPVGYATNVMGGAGGPLAVYVVAIVAAEFGKLVSKETKVDILVTPIVTILVGVGVAFFIAAPIGGGAMVVGTLIKWATTQEPLIMGVIVSVVVGIALTLPISSAAICAALSLTGLAGGAALAGCCANMVGFAVISFKENGWGGVVSQGIGTSMLQMGNIVRNPRIWIPAIAASAITGPLSTCVFKLEMNGAAVSSGMGTCGLVGPIGVWTGWTNPSAEALMDGAAAIVPTTFDWIGLVLISVVLPALLAWAFGVACRKLGWIKDGDMKLS
>NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein
MVKNLNNIAQAGIIAAIYAAATLVCNLVFPAISWGPVQIRLSEALCVVAVLYPSARAGLPIGCAIANLFNIVIAGTGALGFLDVVFGSLATLLGAILCWKLREKPMLAIFMFVITNAVIVPAYLPILCEWTGFYTIPFTDVALDGYYGWMWLFGFVSITISESLTLYVLGLPILHALKKANEK
>NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein
MEAEPESIAVLVANYVWHQCLRLNLCLTPSQMRITTRRLDLCLALMIHDWHQCFGTKGKGARKVLLFFSQIMSGTSDLCLTPSQMRITTRRLDLCLALMIHDWHQCFMSDTNDPCLEPMEAEPENITVLVANYVWHQCFMSDTNDPCLEPMEKGPSDLSLAPVFYVWHQ
>NZ_LT821227.1|WP_079536726.1|1408060_1408978_+|2-ketoisovalerate-ferredoxin-oxidoreductase
MAVNARNISDNELFFGHKACAGCGGALALRHALKVLGPDTTIALPAGCMSAVGFNFPQLCFANNAMITPFAATAAVASGIAAGLEMQGIDTATHPVIGFAGDGGTADIGIQALSGAIDRNEDIIYFCYDNEAYMNTGIQKSGLTPLCASTTTTPAGKNAHGALTQKKNIFEIVAAHGISYAATSSVGYLSDYIKKVEKAQSIRGTKFIHVIAPCPTGWGHAESATAKFAKDVVDCGLWYLAEYEGEQVCGVPGGKFKINKAPKEFSSIEHYLRAQKRFSRIDDDDIRTITASRDSKWKQIKRDWE
>NZ_LT821227.1|WP_079536724.1|1406742_1407924_+|pyruvate-ferredoxin-oxidoreductase
MRHFLSGDEALAEGVRLCRPKVISAYPITPQTVVVERLSEMVEAKTLDAKYMHVESEHSALSAAMGASATGVRTFTATSSQGLLYMAEVLTYAAGGRFPIVMMNANRSTALPWNIYGDQRDSLALLDHGWIQAYAENNQEALDLTLMAYRIAEDKDVSTPFMINLDGFALTHTYETVDIPTQEEADSYLPQYSTANRFDFKNPVNMAYSAGPATNKLFKFAEHDDMVKSLDVISNAEKEFEKIFGRHYSGPVETYRCEDAEFVLVTLGSIAGLARTVVDDLREKGTKAGLLKIRYMRPFPEKQIANALKFAKCFAVLEKDISFGFEGTVFTNVKSAMHNNRADVPGINFIGGLGGDDIAENDIEAIFKECEKCARAGVSQTVYWLSIDEGQVK
>NZ_LT821227.1|WP_079536719.1|1405720_1406743_+|2-oxoacid:acceptor-oxidoreductase-family-protein
MIEIIWHGRGGQGAFTAARLLGAAASISGENSSLAFPTFGPERRGAPMRAFTKIDRRPIGNRSEVKQADYVVYLDETLLAEGWDKELKDTVKNLNADMITSPVVLVNSKKHFNDPRIKSIDASGIATDILGRNIPNTVFLGLICAMCDALSIEDAREAIRHYMPEKLHEKNLAIIDKVANAKEALNKKGGDNETIVASNHGSNSSESRIAINRQNSPEGQTTKIAFKKSEIVNGLSRPNCVIPKLHSEAVSPKEFAHNTCWQAGWLTTKNAGWRTFRPKIDQEKCTGCLKCYMDCPDGCIFKMQESRTVGIDLDFCKGCAMCAEACKFDAIEMIAERSAE
>NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI
MAADTFQRVVLVHYHEIGLKGHNRGRFEQKLVDNIKALTCDFPVSACHRISGRIVVFLKEGTTHDEQVRAQEFIATIPGIQRVSAGFKCLAEYDTMKELAVEALADAGEFQTFKVQARRNHTNFEPDSMVLNREIGEVLCNAFPEKKVKMKEPDVTVNVEVIENQCFVCARSIAGVGGLPVGTSGKVICLLSSGIDSPVAAWKIAKRGATCIGVHFSGRPQTGDESEYLVDDIARVLAKRGCMHQYFVCPIGDYQRKIALSCTPKLRVVLYRRLMFKVANALAEQCGAKAIVTGESLGQVASQTIENMIATSDASEKMVLRPLIGFDKLEIIDEAIRLGTFEISSQDASDCCTLFMPKMPETHAHLDEVKKEEEFFDPSWIDEIVASAELHRV
>NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega
MSVVEPKIHELLNRSENDRFLLCSMASKRAHDINDMMRGQRNRAVSTETAKEIAQASTVKPLSMAFNEIYRGEVSYDPQTIDAIHH
>NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase
MENEYEKLVIISSPSGGGKGTLIKKLLDDVDGVWLSVSATSRQPREGETNGKSYYFMSRDEFKESIEQNGFLEWAEYSGNLYGTPRKYIHDHLDNGDVVLLEIEVQGASDVMKKCPGCHSVFIMPPSLEILESRLRGRNTDSEESIRKRMQAAEFELECAEQYEKIIVNDDLDVAFKELKEYINRVAD
>NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMAKRAENYKWSSFKDLDSEKIDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDEKEFEVIPNSTPSDMLVIDAVKRIVKEKNLGKISALSRSLLRKLVKSLLKLGSNINQISRVTGLTRHQVGILAT
>NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein
MARGFFIDETKCTGCKACVVTCKDKRNLDAGFNLRFVNSQVWGSFPHVRMSYHSRSCNNCKNPACVENCPSGAMSRDNELGVVKVDLDVCIGCGKCAKACPFGAPTIDSDKKKSMKCDFCFDLTKDGQNPACMDVCNSRALEFGDLDELQRAHPDAKGVEGDTRPNTLVLFK
>NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase
MNLEETLKGRDFSRRTFLKGLAVLSAATMLDGCTNKLSNVVEEDAFKKAEEATGEAVWKNAPCWHNCGGTCCLKAQVKGDTIVRLKTDDSHPDSYDYPQQRACVRGLSERLQIVGKERLKYPMKRKHFDPEGKKGKDMRGRDTWERISWDEALDIVASQLKKAKQNYGNKSIYLLDGGEMKRTLALYGGYVAKSGSRSKGCWNKAMEPICGVTAKSHCLNDRMDLMNAKLIILWGCNPAQSSMGMPLLNLRRAKEAGAKIICIDPMFTRTAAVLADEYYPIRPATDTTLLLALSYVIIQKDKEAGGSIIDWDFLNRCTIGFDADHMPEGANVEENYMDYVLGTYDNEPKTPEWASKICGTPVEDINKIAEMIIKNKPTTCLFSWNSARVEKAQHVCLAQMALGSLTGNMGIKGGAFSCSSQESSTNGGPNLIKKGKDRIEEIKNPLSKPKLCTNHHWQDIVSGTWRDGKNGLKPLDIHVIYHSHSATLNQTNNVNKGIEAHHKVDFVVTNHYTFTPECQYSDVVLPVTTPWEKEGEVLQGNREAIIWTEKVIEPYFESKDDAWIAEEIAKRLGVDAYQANPVNNKQRCYNIIAGTTVVKENGKDYEKLVSVTEDDLKELGVKGKPQYGRVPILELKKAGIYQVERHLGDNYGYIANKKLRQNPEANPIKTESGKIELYCKALKKAVDKAGWNKGYAYAKYVPPTEGYEATFKDFENGVKGEYPYQVLGIHDLRGTHTVFNQVNYLREAFPYELEVNPIDAKEKGFKEGEVIEIFNSRGKILRKLHITERVMPGVIVIHEGVWVDMKDGRCIAGSPNVLTGDFPSGPDVESWNACIADMRKSSVSLEEDWKVDLAVKLDG
>NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein
MDNDKTDIFNFLQEKEEFYSFMSMVFMDSPTNAFCTTLWGMLNEDYFPLADNNIELHALCLSLREKLRETNLEEFTQALSQEYYNLFFDPCGINVSPWQSSYTNKEQLLFQETDGQAKAMYRRYGYKVEDNHLPGDHIAIELDFLSKLSSRELKNIDSVIQGGNKQLLSDIQNFICKHILSWIDEFIDSLKDNASVYYLLFASMVKIVCEEDKAFMPNL
>NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein
MFIQRSKRYFLTLLILTVFFALSLAGCASNNSTWSNNAEDEVKQQLTEMPNFESTDLDGNTITGDVFSNKKFTVVNFWGTYCSPCISEMQDLAEWSKGMEPDIQLIGVVCDVDSKGSSSFDTAVEICNSKGVKFTNVLANDSLAPAIQTLVGIPTTYIVDSNRQVVAGPIVGAQVDAYKQALQDCLAK
>NZ_LT821227.1|WP_079536985.1|1429960_1430113_+|thioredoxin
MFQDNKTKLIATIALLVVAVSFIAVGIARGEIEVVFTRAVNICLECIGLG
>NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein
MKIKNIKTEAKRKIIQVVAFGFSNANIQNFAGGQIYKGNWKNFCNPGLNCYSCPAATTACPIGALQAVAGSSKFDFSFYVVGFLLALGVVFGRAICGFLCPFGLIQELIHKIPSPKVKLPRPFRYLKYVILIGFVIIAPIAFTEFGTGAPAFCEWICPVGTLEAGIPLLATQPMLQSLVGFLFSWKMIILVITIVMCTLCERFFCKALCPLGAIYGLLNKVSLYSMKFMPQNCISCGKCAKVCPMDIDPTKEPNSIECIRCKKCVCACNFEALNLSFFEHKKKKEANANPAQ

Crispr_ID: NZ_LT821227_12

• CRISPR_ID: NZ_LT821227_12
• CRISPR_location: 1421733-1422034
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NZ_LT821227_12

Consensus_repeat	Method
ANTTCATGACTGGCACTANTG	CRT

spacers of NZ_LT821227_12

>12.1|1421754|24|NZ_LT821227|CRT
CTGAACGTCATTCACTAGCGTTGA
>12.2|1421799|25|NZ_LT821227|CRT
CTTTGCGTCTGTCACCAGTGCTGCG
>12.3|1421845|44|NZ_LT821227|CRT
ATTTGCGTTTGTTACGATTGCTGCATGTCTTTTTCTAGCGTTAA
>12.4|1421910|39|NZ_LT821227|CRT
AAACATCACTAATCAATCACGTCTGTCACCAGTGCTGGG
>12.5|1421970|44|NZ_LT821227|CRT
AAGCATTAGCATTGATTCATCACTGGCGTTAGTGCACAATAACT

CRISPR arrays and Neighbor proteins around NZ_LT821227_12

CRISPR arrays

The CRISPR arrays of NZ_LT821227_12

>merge|NZ_LT821227|12|1421733-1422034|CRT
AGTTTATGTCTGGCACCAGTACTGAACGTCATTCACTAGCGTTGAAATTCATGACTGGCACTAATGCTTTGCGTCTGTCACCAGTGCTGCGAATTCATGACTGGCACTAATGATTTGCGTTTGTTACGATTGCTGCATGTCTTTTTCTAGCGTTAAAATTCATGACTGGCACTAATGAAACATCACTAATCAATCACGTCTGTCACCAGTGCTGGGAATCCATGACTGGTACTAATGAAGCATTAGCATTGATTCATCACTGGCGTTAGTGCACAATAACTGTTTCATGACTGGCACTTTTG

>NZ_LT821227|12|2|1421733-1422034|CRT
AGTTTATGTCTGGCACCAGTA	CTGAACGTCATTCACTAGCGTTGA
AATTCATGACTGGCACTAATG	CTTTGCGTCTGTCACCAGTGCTGCG
AATTCATGACTGGCACTAATG	ATTTGCGTTTGTTACGATTGCTGCATGTCTTTTTCTAGCGTTAA
AATTCATGACTGGCACTAATG	AAACATCACTAATCAATCACGTCTGTCACCAGTGCTGGG
AATCCATGACTGGTACTAATG	AAGCATTAGCATTGATTCATCACTGGCGTTAGTGCACAATAACT
GTTTCATGACTGGCACTTTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	unknown	unknown	gnl|CDD|238233
NZ_LT821227.1|WP_079536775.1|1434142_1434661_-|metallophosphoesterase-family-protein	unknown	unknown	gnl|CDD|378975
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|239171
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl|CDD|131996
NZ_LT821227.1|WP_079536985.1|1429960_1430113_+|thioredoxin	unknown	unknown	unknown
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl|CDD|234960
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	unknown	unknown	gnl|CDD|377623
NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	unknown	unknown	gnl|CDD|223728
NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|274004
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl|CDD|379113
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	unknown	unknown	gnl|CDD|239264
NZ_LT821227.1|WP_079536772.1|1432641_1433427_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380358
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	unknown	unknown	gnl|CDD|376858
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl|CDD|225212
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	unknown	unknown	gnl|CDD|234719
NZ_LT821227.1|WP_079536770.1|1431860_1432253_-|hypothetical-protein	unknown	unknown	unknown
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl|CDD|213597
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	unknown	unknown	gnl|CDD|376616
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	unknown	unknown	gnl|CDD|234744

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein	gnl|CDD|238233	cd00400, Voltage_gated_ClC, CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This domain is found in the halogen ions (Cl-, Br- and I-) transport proteins of the ClC family. The ClC channels are found in all three kingdoms of life and perform a variety of functions including cellular excitability regulation, cell volume regulation, membrane potential stabilization, acidification of intracellular organelles, signal transduction, transepithelial transport in animals, and the extreme acid resistance response in eubacteria. They lack any structural or sequence similarity to other known ion channels and exhibit unique properties of ion permeation and gating. Unlike cation-selective ion channels, which form oligomers containing a single pore along the axis of symmetry, the ClC channels form two-pore homodimers with one pore per subunit without axial symmetry. Although lacking the typical voltage-sensor found in cation channels, all studied ClC channels are gated (opened and closed) by transmembrane voltage. The gating is conferred by the permeating ion itself, acting as the gating charge. In addition, eukaryotic and some prokaryotic ClC channels have two additional C-terminal CBS (cystathionine beta synthase) domains of putative regulatory function.	4.00741e-39
NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase	gnl|CDD|239171	cd02770, MopB_DmsA-EC, This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a predicted N-terminal iron-sulfur [4Fe-4S] cluster binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein	gnl|CDD|131996	TIGR02951, anaerobic_dimethyl_sulfoxide_reductase_subunit_B, DMSO reductase, iron-sulfur subunit. This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.	9.25921e-55
NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI	gnl|CDD|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	3.87954e-146
NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein	gnl|CDD|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	2.19199e-31
NZ_LT821227.1|WP_079536775.1|1434142_1434661_-|metallophosphoesterase-family-protein	gnl|CDD|378975	pfam12850, Metallophos_2, Calcineurin-like phosphoesterase superfamily domain. Members of this family are part of the Calcineurin-like phosphoesterase superfamily.	3.4659e-24
NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein	gnl|CDD|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.4286e-31
NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein	gnl|CDD|274004	TIGR02163, Ferredoxin-type_protein_NapH_homolog, ferredoxin-type protein, NapH/MauN family. Most members of this family are the NapH protein, found next to NapG,in operons that encode the periplasmic nitrate reductase. Some species with this reductase lack NapC but accomplish electron transfer to NapAB in some other manner, likely to involve NapH, NapG, and/or some other protein. A few members of this protein are designated MauN and are found in methylamine utilization operons in species that appear to lack a periplasmic nitrate reductase.	2.98168e-23
NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC	gnl|CDD|379113	pfam13303, PTS_EIIC_2, Phosphotransferase system, EIIC. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.	3.07888e-81
NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein	gnl|CDD|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.62298e-18
NZ_LT821227.1|WP_079536772.1|1432641_1433427_+|cupin-domain-containing-protein	gnl|CDD|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	8.88157e-22
NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein	gnl|CDD|376858	pfam02613, Nitrate_red_del, Nitrate reductase delta subunit. This family is the delta subunit of the nitrate reductase enzyme, The delta subunit is not part of the nitrate reductase enzyme but is most likely needed for assembly of the multi-subunit enzyme complex. In the absence of the delta subunit the core alpha beta enzyme complex is unstable. The delta subunit is essential for enzyme activity in vivo and in vitro. The nitrate reductase enzyme, EC:1.7.99.4 catalyze the conversion of nitrite to nitrate via the reduction of an acceptor. The nitrate reductase enzyme is composed of three subunits. Nitrate is the most widely used alternative electron acceptor after oxygen. This family also now contains the family TorD, a family of cytoplasmic chaperone proteins; like many prokaryotic molybdoenzymes, the TMAO reductase (TorA) of Escherichia coli requires the insertion of a bis(molybdopterin guanine dinucleotide) molybdenum (bis(MGD)Mo) cofactor in its catalytic site to be active and translocated to the periplasm. The TorD chaperone increases apoTorA activation up to four-fold, allowing maturation of most of the apoprotein. Therefore TorD is involved in the first step of TorA maturation to make it competent to receive the cofactor.	9.22114e-22
NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.28417e-49
NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	4.43116e-96
NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein	gnl|CDD|213597	TIGR01259, ComE_operon_protein_1, comEA protein. This model describes the ComEA protein in bacteria. The com E locus is obligatory for bacterial cell competence - the process of internalizing the exogenous added DNA. Lesions in the loci has been variously described for the appearance of competence-related pheonotypes and impairment of competence, suggesting their intimate functional role in bacterial transformation. [Cellular processes, DNA transformation].	8.70833e-29
NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase	gnl|CDD|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	2.31315e-09
NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega	gnl|CDD|234744	PRK00392, rpoZ, DNA-directed RNA polymerase subunit omega; Reviewed.	4.46812e-08

Protein sequences

>NZ_LT821227.1|WP_079536755.1|1421128_1421695_-|guanylate-kinase
MENEYEKLVIISSPSGGGKGTLIKKLLDDVDGVWLSVSATSRQPREGETNGKSYYFMSRDEFKESIEQNGFLEWAEYSGNLYGTPRKYIHDHLDNGDVVLLEIEVQGASDVMKKCPGCHSVFIMPPSLEILESRLRGRNTDSEESIRKRMQAAEFELECAEQYEKIIVNDDLDVAFKELKEYINRVAD
>NZ_LT821227.1|WP_079536753.1|1420843_1421104_-|DNA-directed-RNA-polymerase-subunit-omega
MSVVEPKIHELLNRSENDRFLLCSMASKRAHDINDMMRGQRNRAVSTETAKEIAQASTVKPLSMAFNEIYRGEVSYDPQTIDAIHH
>NZ_LT821227.1|WP_079536750.1|1419658_1420840_-|tRNA-4-thiouridine(8)-synthase-ThiI
MAADTFQRVVLVHYHEIGLKGHNRGRFEQKLVDNIKALTCDFPVSACHRISGRIVVFLKEGTTHDEQVRAQEFIATIPGIQRVSAGFKCLAEYDTMKELAVEALADAGEFQTFKVQARRNHTNFEPDSMVLNREIGEVLCNAFPEKKVKMKEPDVTVNVEVIENQCFVCARSIAGVGGLPVGTSGKVICLLSSGIDSPVAAWKIAKRGATCIGVHFSGRPQTGDESEYLVDDIARVLAKRGCMHQYFVCPIGDYQRKIALSCTPKLRVVLYRRLMFKVANALAEQCGAKAIVTGESLGQVASQTIENMIATSDASEKMVLRPLIGFDKLEIIDEAIRLGTFEISSQDASDCCTLFMPKMPETHAHLDEVKKEEEFFDPSWIDEIVASAELHRV
>NZ_LT821227.1|WP_162273050.1|1418390_1419074_-|helix-hairpin-helix-domain-containing-protein
MPFQEFASNFKEDEKEKNQKPVYMVGIALLLIVAIAYFAFNVFTTGENSGFEVESVNSKDDVVDSKKIFVHVAGEVNNPGLQELDADARVSQAIELAGGATENADLNSVNLAKKCEDGEQIIIPAKVEPEVDADGAADETLSGSAAKRSSGASTLQGSGGASGAGKVNINTADASLLQTISGIGPSKAQKIIEYRKQNGSFKSVDDLTNVSGIGVKTLESIRSQICV
>NZ_LT821227.1|WP_147571570.1|1415470_1417888_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MKIRKKKFGSIHGAGHDFAISTGEQGANFDVVIDDKTPRKPSMPFLLPCSLILWGSCLLSFLGTRSFDDSMKNTLLSVFAFGLLISLFACVHKQRRWLFLLLSFLMLGATLGVYKNVSLESNAIIALNSSVAEIDAQVLEDSTTGEFGNQTILSLNSKDFRDLRVLAYLDKNTCVLVGEKLKVKGTFKSLKPESKDFNFNRSVCSILKVSKAETVSINPVLSAVVNMRRDSIRNFETFGGQCGGLLQALVCGYKNTIEDDGTYEEFKVCGLAHTVAVSGAHLAIVVSFFLLLLKKFKVSHRASSFSSVAIVLCYLLFSGIPISAVRSAIMVVLCLIAGVQERRADSLNALSLCIILFIVADASTCTSVSLYLSSASTFGIIVFARLFSSWADCRNKVANGIIIQPIALTMAANLMTLPFSAAIFSQISTISVIANMIATPLFSAACVFGLLTALISIFFPAIASFCCFGASVVAFPLYECVEILGRIPFACIPLDFDVVLSILFSALLALSLIVVWPKLSRRLACASLSVCIMLPFAFVFVSFIVPQNRIAFIDVGQGDAILIQSNGCNFLVDTGNNETKLRTGLAKLGVFSLDGVLITHHDDDHMGCLEVLRSYESIGAVNSAADAKTCACEGCNRLRSAATEATGKELCGLTVGDCVRAGNFSCKVVWPMEFSNEGGNEDSVCLKVSCNANSDSEAEFCALLTGDAEKEPLRQLLQQENLGTIDIFKIGHHGSKISVDDALLDELEPSVALISVGKGNRYGHPSSEALGLLQKHDVRVFCTDELGTIIVTPKFPTGFSVSTHG
>NZ_LT821227.1|WP_079536740.1|1413445_1414783_-|chloride-channel-protein
MKNGKNKDKEFVGEVGKPLESASEKAEIGFGMVLLAVFIGFVIGLFVWAVFWASSALTQLLWVDSNNLISGLLINANIPTWWLPLAFCVSGGLIIGMWTSRVGGEPELLETVMEKVKTTGGYSLKKPGASVVGFLLPIVCGGSIGPEAGLTGIIAAACTRIGTSLKAAGIRVKLLTDTTLSAALSAIFASPFAGVVTTAEDCMNDFDPSNFQFHRRAKLVLYTASAIGATLGIALFTSIFGTESGIPRFGGVTPGINKLWWAIPCVISAYAAILIFHGSSFAFKKLGEKMGERQVLKPVIAGLVLGILAIPLPYLLFSGESQSFELMEMWTVVPGSLLIATGLLKCAMTPLCINFGWKGGHFFPIIFAGIALGYGVASIGGFNDMFCVAITTATLVAGIQRKPLMAIGTLLLCFPVESFPWFGIACLIGAYLPVPTKLLAKQAKQ
>NZ_LT821227.1|WP_079536738.1|1412654_1413185_+|flavodoxin-family-protein
MKIVVLSASPREGGNTSIMVDAFKEGAEIAGNTVEVIDVASKNIAPCRACQYCFEHEGQCAQEDDMTAIRKTLKEADMLVLASPIYWFDVSAQLKLAIDRLYAFGGTGFNFSKVAMLLDSGSDGVYEAATAAFKGMCSYLKWENMGIITIPGMVNKGDMANNPKLDDVRKFGASLK
>NZ_LT821227.1|WP_079536735.1|1411399_1412506_-|PTS-sugar-transporter-subunit-IIC
MDKVKAFFKRKDVEVSLKRYGVDALSAMAQGLFCTLLVGTILDTIGTQFGIAFLTTSLIDIAGTGYTIGKFASAMVGPAMAVAIGYALNAPAMVLFSLIPVGYATNVMGGAGGPLAVYVVAIVAAEFGKLVSKETKVDILVTPIVTILVGVGVAFFIAAPIGGGAMVVGTLIKWATTQEPLIMGVIVSVVVGIALTLPISSAAICAALSLTGLAGGAALAGCCANMVGFAVISFKENGWGGVVSQGIGTSMLQMGNIVRNPRIWIPAIAASAITGPLSTCVFKLEMNGAAVSSGMGTCGLVGPIGVWTGWTNPSAEALMDGAAAIVPTTFDWIGLVLISVVLPALLAWAFGVACRKLGWIKDGDMKLS
>NZ_LT821227.1|WP_079536732.1|1410649_1411201_-|QueT-transporter-family-protein
MVKNLNNIAQAGIIAAIYAAATLVCNLVFPAISWGPVQIRLSEALCVVAVLYPSARAGLPIGCAIANLFNIVIAGTGALGFLDVVFGSLATLLGAILCWKLREKPMLAIFMFVITNAVIVPAYLPILCEWTGFYTIPFTDVALDGYYGWMWLFGFVSITISESLTLYVLGLPILHALKKANEK
>NZ_LT821227.1|WP_147571568.1|1409944_1410454_+|hypothetical-protein
MEAEPESIAVLVANYVWHQCLRLNLCLTPSQMRITTRRLDLCLALMIHDWHQCFGTKGKGARKVLLFFSQIMSGTSDLCLTPSQMRITTRRLDLCLALMIHDWHQCFMSDTNDPCLEPMEAEPENITVLVANYVWHQCFMSDTNDPCLEPMEKGPSDLSLAPVFYVWHQ
>NZ_LT821227.1|WP_079536757.1|1422364_1423135_-|transposase
MSRPPRCNSPIGVLNIGQKGHNDQVIFYSDEDRGYYIECLQNACDKFGIVLLAYVLMSNHIHALFYGDIKKCDKVFRSIGSRYVKWFNRKYGRSGTLWNSRFYSKPVQDELQFLQTAAYIFNNPVKAGMAKRAENYKWSSFKDLDSEKIDAKAKEILDTTLSISYLKQYTHDVAESQMSPDDEKEFEVIPNSTPSDMLVIDAVKRIVKEKNLGKISALSRSLLRKLVKSLLKLGSNINQISRVTGLTRHQVGILAT
>NZ_LT821227.1|WP_079536759.1|1424283_1424802_-|4Fe-4S-dicluster-domain-containing-protein
MARGFFIDETKCTGCKACVVTCKDKRNLDAGFNLRFVNSQVWGSFPHVRMSYHSRSCNNCKNPACVENCPSGAMSRDNELGVVKVDLDVCIGCGKCAKACPFGAPTIDSDKKKSMKCDFCFDLTKDGQNPACMDVCNSRALEFGDLDELQRAHPDAKGVEGDTRPNTLVLFK
>NZ_LT821227.1|WP_079536761.1|1424794_1427374_-|molybdopterin-dependent-oxidoreductase
MNLEETLKGRDFSRRTFLKGLAVLSAATMLDGCTNKLSNVVEEDAFKKAEEATGEAVWKNAPCWHNCGGTCCLKAQVKGDTIVRLKTDDSHPDSYDYPQQRACVRGLSERLQIVGKERLKYPMKRKHFDPEGKKGKDMRGRDTWERISWDEALDIVASQLKKAKQNYGNKSIYLLDGGEMKRTLALYGGYVAKSGSRSKGCWNKAMEPICGVTAKSHCLNDRMDLMNAKLIILWGCNPAQSSMGMPLLNLRRAKEAGAKIICIDPMFTRTAAVLADEYYPIRPATDTTLLLALSYVIIQKDKEAGGSIIDWDFLNRCTIGFDADHMPEGANVEENYMDYVLGTYDNEPKTPEWASKICGTPVEDINKIAEMIIKNKPTTCLFSWNSARVEKAQHVCLAQMALGSLTGNMGIKGGAFSCSSQESSTNGGPNLIKKGKDRIEEIKNPLSKPKLCTNHHWQDIVSGTWRDGKNGLKPLDIHVIYHSHSATLNQTNNVNKGIEAHHKVDFVVTNHYTFTPECQYSDVVLPVTTPWEKEGEVLQGNREAIIWTEKVIEPYFESKDDAWIAEEIAKRLGVDAYQANPVNNKQRCYNIIAGTTVVKENGKDYEKLVSVTEDDLKELGVKGKPQYGRVPILELKKAGIYQVERHLGDNYGYIANKKLRQNPEANPIKTESGKIELYCKALKKAVDKAGWNKGYAYAKYVPPTEGYEATFKDFENGVKGEYPYQVLGIHDLRGTHTVFNQVNYLREAFPYELEVNPIDAKEKGFKEGEVIEIFNSRGKILRKLHITERVMPGVIVIHEGVWVDMKDGRCIAGSPNVLTGDFPSGPDVESWNACIADMRKSSVSLEEDWKVDLAVKLDG
>NZ_LT821227.1|WP_079536764.1|1427802_1428462_-|molecular-chaperone-TorD-family-protein
MDNDKTDIFNFLQEKEEFYSFMSMVFMDSPTNAFCTTLWGMLNEDYFPLADNNIELHALCLSLREKLRETNLEEFTQALSQEYYNLFFDPCGINVSPWQSSYTNKEQLLFQETDGQAKAMYRRYGYKVEDNHLPGDHIAIELDFLSKLSSRELKNIDSVIQGGNKQLLSDIQNFICKHILSWIDEFIDSLKDNASVYYLLFASMVKIVCEEDKAFMPNL
>NZ_LT821227.1|WP_157887306.1|1429119_1429686_+|redoxin-family-protein
MFIQRSKRYFLTLLILTVFFALSLAGCASNNSTWSNNAEDEVKQQLTEMPNFESTDLDGNTITGDVFSNKKFTVVNFWGTYCSPCISEMQDLAEWSKGMEPDIQLIGVVCDVDSKGSSSFDTAVEICNSKGVKFTNVLANDSLAPAIQTLVGIPTTYIVDSNRQVVAGPIVGAQVDAYKQALQDCLAK
>NZ_LT821227.1|WP_079536985.1|1429960_1430113_+|thioredoxin
MFQDNKTKLIATIALLVVAVSFIAVGIARGEIEVVFTRAVNICLECIGLG
>NZ_LT821227.1|WP_079536768.1|1430295_1431174_+|4Fe-4S-binding-protein
MKIKNIKTEAKRKIIQVVAFGFSNANIQNFAGGQIYKGNWKNFCNPGLNCYSCPAATTACPIGALQAVAGSSKFDFSFYVVGFLLALGVVFGRAICGFLCPFGLIQELIHKIPSPKVKLPRPFRYLKYVILIGFVIIAPIAFTEFGTGAPAFCEWICPVGTLEAGIPLLATQPMLQSLVGFLFSWKMIILVITIVMCTLCERFFCKALCPLGAIYGLLNKVSLYSMKFMPQNCISCGKCAKVCPMDIDPTKEPNSIECIRCKKCVCACNFEALNLSFFEHKKKKEANANPAQ
>NZ_LT821227.1|WP_079536770.1|1431860_1432253_-|hypothetical-protein
MSAGNIKKTVSLVIGIACLVGIFAAEVAANNGVSFEWFDTGIGGTMTTSDLMTVTLAPLAFVVLASVFFFVFRGNRSMISYQVLLLSFVSFILCCQISSAEGFDVNSVDSIALVIGVFGTIVLSLGNYAK
>NZ_LT821227.1|WP_079536772.1|1432641_1433427_+|cupin-domain-containing-protein
MKEKIGQSFSVARDNPPVSGCTVSRAILQGENPLIYFSLAKNTDISAEVFPYHKLILVNEGELEVYGFKDSSACSNHEDKYKRKAESDISSPTANKSGQEDQQLNYENPNSTSTGQKLLRKGESILTPTNVPVGFRSKSSAVYTELEIRRSDIMNEAVHPGEIFVLKDILPYQEGRIVNMDIAHNDKMKFVMMAFDEGQGLSEHSAPGEALIFALDGKGIIGYEGEEHSIKAGECFHFAKNGRHWVKADGKFKMALLLTLE
>NZ_LT821227.1|WP_079536775.1|1434142_1434661_-|metallophosphoesterase-family-protein
MLVGIVSDTHGTLPLKAEDLLTKCDHIVHAGDICVPDILRQLRRIAPTTAVMGNNDFREYGDDVDKFAYVVLDGVLLTVTHYPQKIRPRTEKLLKENDEFADFAGEIVAVHGHTHTARLETGSSAAPAGYLICPGSLAFPRTPAGETLGFAEFESGVVKNIWIEALDGRCIL

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT821227_1	1.2|459|34|NZ_LT821227|PILER-CR	459-492	34	NZ_LT821227.1	988340-988373	0	1.0

1. spacer 1.2|459|34|NZ_LT821227|PILER-CR matches to position: 988340-988373, mismatch: 0, identity: 1.0

cgcttgaagactgtcatcaatggcagcactggca	CRISPR spacer
cgcttgaagactgtcatcaatggcagcactggca	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT821227_12	12.2|1421799|25|NZ_LT821227|CRT	1421799-1421823	25	NC_019699	Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence	275602-275626	5	0.8
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	MT446405	UNVERIFIED: Escherichia virus TH32, complete genome	18209-18239	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	MT446408	UNVERIFIED: Escherichia virus TH35, complete genome	47087-47117	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	NC_048073	Escherichia phage FEC19, complete genome	61399-61429	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	MN176217	Escherichia phage vB_Eco4M-7, complete genome	15030-15060	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	MH051335	Escherichia phage vB_EcoM-Ro157lw, complete genome	8946-8976	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	JX128258	Escherichia phage ECML-117, complete genome	13728-13758	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	MK903282	Escherichia phage Mansfield, complete genome	8890-8920	6	0.806
NZ_LT821227_5	5.3|992581|31|NZ_LT821227|CRISPRCasFinder	992581-992611	31	NC_048195	Escherichia phage vB_EcoM_WFC, complete genome	9044-9074	6	0.806

1. spacer 12.2|1421799|25|NZ_LT821227|CRT matches to NC_019699 (Chroococcidiopsis thermalis PCC 7203 plasmid pCHRO.01, complete sequence) position: , mismatch: 5, identity: 0.8

ctttgcgtctgtcaccagtgctgcg	CRISPR spacer
taatgcgtctgtcaccagtgctgtc	Protospacer
.  ********************. 

2. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to MT446405 (UNVERIFIED: Escherichia virus TH32, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

3. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to MT446408 (UNVERIFIED: Escherichia virus TH35, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

4. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to NC_048073 (Escherichia phage FEC19, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

5. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to MN176217 (Escherichia phage vB_Eco4M-7, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

6. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to MH051335 (Escherichia phage vB_EcoM-Ro157lw, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

7. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to JX128258 (Escherichia phage ECML-117, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

8. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to MK903282 (Escherichia phage Mansfield, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.*** 

9. spacer 5.3|992581|31|NZ_LT821227|CRISPRCasFinder matches to NC_048195 (Escherichia phage vB_EcoM_WFC, complete genome) position: , mismatch: 6, identity: 0.806

acagatgacagacatgaatgtgtg-tcatcgg	CRISPR spacer
caagatgacagacttgaatgtgtgaacgtcg-	Protospacer
  *********** **********  *.***