CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT906446	Megamonas hypermegale strain NCTC10570 chromosome 1	9 crisprs	WYL,cas14j,cas6,DEDDh,cas3,cas2,cas1,cas4,cas5,cas7b,cas8b1,csa3,cas10,csm3gr7,csx10gr5,csx19	4	16	5	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT906446_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_1

555784-558118

Orphan

Consensus_repeat	Method
GATTAATAGCAACATACGATGTATTTGAAT	PILER-CR
GATTAATAGCAACATACGATGTATTTGAAT	CRISPRCasFinder
GATTAATAGCAACATACGATGTATTTGAAT	CRT

35 spacers

The CRISPR arrays of NZ_LT906446_1

>merge|NZ_LT906446|1|555784-558118|PILER-CR,CRISPRCasFinder,CRT
GATTAATAGCAACATACGATGTATTTGAATCAAAAATATAGCATAAATAAAAAATAGTTTTTACTGGATTAATAGCAACATACGATGTATTTGAATACAAAATAAGTTTTATCAATTATTTTTTTCTGGATAGATTAATAGCAACATACGATGTATTTGAATTTGCTTGCCCCTAAAATAGAGCCTAAAAACATTGCTGATTAATAGCAACATACGATGTATTTGAATGAAATTAATCCAATAAATGACCATAATAAATCTTCGATTAATAGCAACATACGATGTATTTGAATTTTTATATTCCTCCAATTTTAATATCCGCAGTTTATGATTAATAGCAACATACGATGTATTTGAATACGTTTGTTAATGTATGTTGGATATGGATACATAGGATTAATAGCAACATACGATGTATTTGAATTTCCCCAAATAAAACCAAATAATTATTGTTCGTATAAGATTAATAGCAACATACGATGTATTTGAATTGAATAAAAGCAATTTCATTTTCTTTTATTCCTTGATTAATAGCAACATACGATGTATTTGAATGAATTTATTTGGGATGACAGACCCGAACATGGCTAAGATTAATAGCAACATACGATGTATTTGAATATTCTGTAACGTCTATTGTTGGCCACAATTATTTTAGATTAATAGCAACATACGATGTATTTGAATAAAGCAGCTTATGTAACAGGTACAGCACTTCTTGCGATTAATAGCAACATACGATGTATTTGAATTAAGTTTTTGCGTTTGCCACTTTATTTCCTCCTTTCTGATTAATAGCAACATACGATGTATTTGAATTTGTAATGGCATTTTATACGGGAAACAAGACAGTCGCGATTAATAGCAACATACGATGTATTTGAATAATGTTATTTTTCGTGATGACATTATTATGTATAGCGATTAATAGCAACATACGATGTATTTGAATTTGACTAAATAAAAGATGTTTTCATTGCCAATTTTGGATTAATAGCAACATACGATGTATTTGAATGGAACTATTTCCTACAGGTAAAAAGTTGATTATTACGATTAATAGCAACATACGATGTATTTGAATTCTATTGAATATAGAAAAGCGTTTATGAATTATGTGATTAATAGCAACATACGATGTATTTGAATTAATATATTCACCATTTGATACACCGATTAATCTAGATTAATAGCAACATACGATGTATTTGAATGTAAGTGTATTTGACCAATACAATATGCTTGAAAAAGATTAATAGCAACATACGATGTATTTGAATGCGCAAGGCTTGTACTGGTCTGACGCTCCAGAAACAGATTAATAGCAACATACGATGTATTTGAATCTGAGTAAAAAGTATTGATTTTATTGGGTTTGTGGCGATTAATAGCAACATACGATGTATTTGAATCTATCCAGCTGTTTCAAGAAAAAAGAATCAACTTTAGATTAATAGCAACATACGATGTATTTGAATTTGATTGGTGCAAATGTTCTACTTTTAGATGTTAAAGATTAATAGCAACATACGATGTATTTGAATATTGCACTTCCGTTACCAAAACCACGATTCCAGCCGGATTAATAGCAACATACGATGTATTTGAATTGCGCGCTCCAAATATTGCCAACAGCACCAACAACAGATTAATAGCAACATACGATGTATTTGAATGACGTTGCGAAATTACAGCTTATTAACGGAGGTTAGATTAATAGCAACATACGATGTATTTGAATTCTGTTGGGACTTCTTTACCAATGTCTTTAGCAGCTGATTAATAGCAACATACGATGTATTTGAATGCTTGAAATTTTCGTTGCGGTTTTGATGCTAAAATTGATTAATAGCAACATACGATGTATTTGAATTTTTTTAAATTATTTAATTGTTCTTGAGCTGATTTGATTAATAGCAACATACGATGTATTTGAATGTATCTAAGTTATCCAATATCCAAAATGCTAACTTTGATTAATAGCAACATACGATGTTTTTGAATCCCAAATTTCCGTTTCCGCCTGCCCACGCTCGGCTGATTAATAGCAACATACGATGTTTTTGAATTTTGGTATTGTGTAAGTATGTTGTGTTTTTAATACGATTAATAGCAACATACGATGTTTTTGAATTTTACGATTGCGCGGGCGTCTATAATAGTCTGCATTACGATTAATAGCAACATACGATGTATTTGAATTAAGTGTAAACATTTACAATTATGTTCAATTATGTGGATTAATAGCAATATATGATATATTTGAATTCTATAACTATTTGTGTTAAAATCTTTTGACGTTGAAGATTAATAGCAATATAAAATATATTTAAAT

>NZ_LT906446|1|1|555784-557985|PILER-CR
GATTAATAGCAACATACGATGTATTTGAAT	CAAAAATATAGCATAAATAAAAAATAGTTTTTACTG
GATTAATAGCAACATACGATGTATTTGAAT	ACAAAATAAGTTTTATCAATTATTTTTTTCTGGATA
GATTAATAGCAACATACGATGTATTTGAAT	TTGCTTGCCCCTAAAATAGAGCCTAAAAACATTGCT
GATTAATAGCAACATACGATGTATTTGAAT	GAAATTAATCCAATAAATGACCATAATAAATCTTC
GATTAATAGCAACATACGATGTATTTGAAT	TTTTATATTCCTCCAATTTTAATATCCGCAGTTTAT
GATTAATAGCAACATACGATGTATTTGAAT	ACGTTTGTTAATGTATGTTGGATATGGATACATAG
GATTAATAGCAACATACGATGTATTTGAAT	TTCCCCAAATAAAACCAAATAATTATTGTTCGTATAA
GATTAATAGCAACATACGATGTATTTGAAT	TGAATAAAAGCAATTTCATTTTCTTTTATTCCTT
GATTAATAGCAACATACGATGTATTTGAAT	GAATTTATTTGGGATGACAGACCCGAACATGGCTAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTCTGTAACGTCTATTGTTGGCCACAATTATTTTA
GATTAATAGCAACATACGATGTATTTGAAT	AAAGCAGCTTATGTAACAGGTACAGCACTTCTTGC
GATTAATAGCAACATACGATGTATTTGAAT	TAAGTTTTTGCGTTTGCCACTTTATTTCCTCCTTTCT
GATTAATAGCAACATACGATGTATTTGAAT	TTGTAATGGCATTTTATACGGGAAACAAGACAGTCGC
GATTAATAGCAACATACGATGTATTTGAAT	AATGTTATTTTTCGTGATGACATTATTATGTATAGC
GATTAATAGCAACATACGATGTATTTGAAT	TTGACTAAATAAAAGATGTTTTCATTGCCAATTTTG
GATTAATAGCAACATACGATGTATTTGAAT	GGAACTATTTCCTACAGGTAAAAAGTTGATTATTAC
GATTAATAGCAACATACGATGTATTTGAAT	TCTATTGAATATAGAAAAGCGTTTATGAATTATGT
GATTAATAGCAACATACGATGTATTTGAAT	TAATATATTCACCATTTGATACACCGATTAATCTA
GATTAATAGCAACATACGATGTATTTGAAT	GTAAGTGTATTTGACCAATACAATATGCTTGAAAAA
GATTAATAGCAACATACGATGTATTTGAAT	GCGCAAGGCTTGTACTGGTCTGACGCTCCAGAAACA
GATTAATAGCAACATACGATGTATTTGAAT	CTGAGTAAAAAGTATTGATTTTATTGGGTTTGTGGC
GATTAATAGCAACATACGATGTATTTGAAT	CTATCCAGCTGTTTCAAGAAAAAAGAATCAACTTTA
GATTAATAGCAACATACGATGTATTTGAAT	TTGATTGGTGCAAATGTTCTACTTTTAGATGTTAAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTGCACTTCCGTTACCAAAACCACGATTCCAGCCG
GATTAATAGCAACATACGATGTATTTGAAT	TGCGCGCTCCAAATATTGCCAACAGCACCAACAACA
GATTAATAGCAACATACGATGTATTTGAAT	GACGTTGCGAAATTACAGCTTATTAACGGAGGTTA
GATTAATAGCAACATACGATGTATTTGAAT	TCTGTTGGGACTTCTTTACCAATGTCTTTAGCAGCT
GATTAATAGCAACATACGATGTATTTGAAT	GCTTGAAATTTTCGTTGCGGTTTTGATGCTAAAATT
GATTAATAGCAACATACGATGTATTTGAAT	TTTTTTAAATTATTTAATTGTTCTTGAGCTGATTT
GATTAATAGCAACATACGATGTATTTGAAT	GTATCTAAGTTATCCAATATCCAAAATGCTAACTTT
GATTAATAGCAACATACGATGTTTTTGAAT	CCCAAATTTCCGTTTCCGCCTGCCCACGCTCGGCT
GATTAATAGCAACATACGATGTTTTTGAAT	TTTGGTATTGTGTAAGTATGTTGTGTTTTTAATAC
GATTAATAGCAACATACGATGTTTTTGAAT	TTTACGATTGCGCGGGCGTCTATAATAGTCTGCATTAC
GATTAATAGCAACATACGATGTATTTGAAT

>NZ_LT906446|1|1|555784-558118|CRISPRCasFinder
GATTAATAGCAACATACGATGTATTTGAAT	CAAAAATATAGCATAAATAAAAAATAGTTTTTACTG
GATTAATAGCAACATACGATGTATTTGAAT	ACAAAATAAGTTTTATCAATTATTTTTTTCTGGATA
GATTAATAGCAACATACGATGTATTTGAAT	TTGCTTGCCCCTAAAATAGAGCCTAAAAACATTGCT
GATTAATAGCAACATACGATGTATTTGAAT	GAAATTAATCCAATAAATGACCATAATAAATCTTC
GATTAATAGCAACATACGATGTATTTGAAT	TTTTATATTCCTCCAATTTTAATATCCGCAGTTTAT
GATTAATAGCAACATACGATGTATTTGAAT	ACGTTTGTTAATGTATGTTGGATATGGATACATAG
GATTAATAGCAACATACGATGTATTTGAAT	TTCCCCAAATAAAACCAAATAATTATTGTTCGTATAA
GATTAATAGCAACATACGATGTATTTGAAT	TGAATAAAAGCAATTTCATTTTCTTTTATTCCTT
GATTAATAGCAACATACGATGTATTTGAAT	GAATTTATTTGGGATGACAGACCCGAACATGGCTAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTCTGTAACGTCTATTGTTGGCCACAATTATTTTA
GATTAATAGCAACATACGATGTATTTGAAT	AAAGCAGCTTATGTAACAGGTACAGCACTTCTTGC
GATTAATAGCAACATACGATGTATTTGAAT	TAAGTTTTTGCGTTTGCCACTTTATTTCCTCCTTTCT
GATTAATAGCAACATACGATGTATTTGAAT	TTGTAATGGCATTTTATACGGGAAACAAGACAGTCGC
GATTAATAGCAACATACGATGTATTTGAAT	AATGTTATTTTTCGTGATGACATTATTATGTATAGC
GATTAATAGCAACATACGATGTATTTGAAT	TTGACTAAATAAAAGATGTTTTCATTGCCAATTTTG
GATTAATAGCAACATACGATGTATTTGAAT	GGAACTATTTCCTACAGGTAAAAAGTTGATTATTAC
GATTAATAGCAACATACGATGTATTTGAAT	TCTATTGAATATAGAAAAGCGTTTATGAATTATGT
GATTAATAGCAACATACGATGTATTTGAAT	TAATATATTCACCATTTGATACACCGATTAATCTA
GATTAATAGCAACATACGATGTATTTGAAT	GTAAGTGTATTTGACCAATACAATATGCTTGAAAAA
GATTAATAGCAACATACGATGTATTTGAAT	GCGCAAGGCTTGTACTGGTCTGACGCTCCAGAAACA
GATTAATAGCAACATACGATGTATTTGAAT	CTGAGTAAAAAGTATTGATTTTATTGGGTTTGTGGC
GATTAATAGCAACATACGATGTATTTGAAT	CTATCCAGCTGTTTCAAGAAAAAAGAATCAACTTTA
GATTAATAGCAACATACGATGTATTTGAAT	TTGATTGGTGCAAATGTTCTACTTTTAGATGTTAAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTGCACTTCCGTTACCAAAACCACGATTCCAGCCG
GATTAATAGCAACATACGATGTATTTGAAT	TGCGCGCTCCAAATATTGCCAACAGCACCAACAACA
GATTAATAGCAACATACGATGTATTTGAAT	GACGTTGCGAAATTACAGCTTATTAACGGAGGTTA
GATTAATAGCAACATACGATGTATTTGAAT	TCTGTTGGGACTTCTTTACCAATGTCTTTAGCAGCT
GATTAATAGCAACATACGATGTATTTGAAT	GCTTGAAATTTTCGTTGCGGTTTTGATGCTAAAATT
GATTAATAGCAACATACGATGTATTTGAAT	TTTTTTAAATTATTTAATTGTTCTTGAGCTGATTT
GATTAATAGCAACATACGATGTATTTGAAT	GTATCTAAGTTATCCAATATCCAAAATGCTAACTTT
GATTAATAGCAACATACGATGTTTTTGAAT	CCCAAATTTCCGTTTCCGCCTGCCCACGCTCGGCT
GATTAATAGCAACATACGATGTTTTTGAAT	TTTGGTATTGTGTAAGTATGTTGTGTTTTTAATAC
GATTAATAGCAACATACGATGTTTTTGAAT	TTTACGATTGCGCGGGCGTCTATAATAGTCTGCATTAC
GATTAATAGCAACATACGATGTATTTGAAT	TAAGTGTAAACATTTACAATTATGTTCAATTATGTG
GATTAATAGCAATATATGATATATTTGAAT	TCTATAACTATTTGTGTTAAAATCTTTTGACGTTGAA
GATTAATAGCAATATAAAATATATTTAAAT

>NZ_LT906446|1|1|555784-558118|CRT
GATTAATAGCAACATACGATGTATTTGAAT	CAAAAATATAGCATAAATAAAAAATAGTTTTTACTG
GATTAATAGCAACATACGATGTATTTGAAT	ACAAAATAAGTTTTATCAATTATTTTTTTCTGGATA
GATTAATAGCAACATACGATGTATTTGAAT	TTGCTTGCCCCTAAAATAGAGCCTAAAAACATTGCT
GATTAATAGCAACATACGATGTATTTGAAT	GAAATTAATCCAATAAATGACCATAATAAATCTTC
GATTAATAGCAACATACGATGTATTTGAAT	TTTTATATTCCTCCAATTTTAATATCCGCAGTTTAT
GATTAATAGCAACATACGATGTATTTGAAT	ACGTTTGTTAATGTATGTTGGATATGGATACATAG
GATTAATAGCAACATACGATGTATTTGAAT	TTCCCCAAATAAAACCAAATAATTATTGTTCGTATAA
GATTAATAGCAACATACGATGTATTTGAAT	TGAATAAAAGCAATTTCATTTTCTTTTATTCCTT
GATTAATAGCAACATACGATGTATTTGAAT	GAATTTATTTGGGATGACAGACCCGAACATGGCTAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTCTGTAACGTCTATTGTTGGCCACAATTATTTTA
GATTAATAGCAACATACGATGTATTTGAAT	AAAGCAGCTTATGTAACAGGTACAGCACTTCTTGC
GATTAATAGCAACATACGATGTATTTGAAT	TAAGTTTTTGCGTTTGCCACTTTATTTCCTCCTTTCT
GATTAATAGCAACATACGATGTATTTGAAT	TTGTAATGGCATTTTATACGGGAAACAAGACAGTCGC
GATTAATAGCAACATACGATGTATTTGAAT	AATGTTATTTTTCGTGATGACATTATTATGTATAGC
GATTAATAGCAACATACGATGTATTTGAAT	TTGACTAAATAAAAGATGTTTTCATTGCCAATTTTG
GATTAATAGCAACATACGATGTATTTGAAT	GGAACTATTTCCTACAGGTAAAAAGTTGATTATTAC
GATTAATAGCAACATACGATGTATTTGAAT	TCTATTGAATATAGAAAAGCGTTTATGAATTATGT
GATTAATAGCAACATACGATGTATTTGAAT	TAATATATTCACCATTTGATACACCGATTAATCTA
GATTAATAGCAACATACGATGTATTTGAAT	GTAAGTGTATTTGACCAATACAATATGCTTGAAAAA
GATTAATAGCAACATACGATGTATTTGAAT	GCGCAAGGCTTGTACTGGTCTGACGCTCCAGAAACA
GATTAATAGCAACATACGATGTATTTGAAT	CTGAGTAAAAAGTATTGATTTTATTGGGTTTGTGGC
GATTAATAGCAACATACGATGTATTTGAAT	CTATCCAGCTGTTTCAAGAAAAAAGAATCAACTTTA
GATTAATAGCAACATACGATGTATTTGAAT	TTGATTGGTGCAAATGTTCTACTTTTAGATGTTAAA
GATTAATAGCAACATACGATGTATTTGAAT	ATTGCACTTCCGTTACCAAAACCACGATTCCAGCCG
GATTAATAGCAACATACGATGTATTTGAAT	TGCGCGCTCCAAATATTGCCAACAGCACCAACAACA
GATTAATAGCAACATACGATGTATTTGAAT	GACGTTGCGAAATTACAGCTTATTAACGGAGGTTA
GATTAATAGCAACATACGATGTATTTGAAT	TCTGTTGGGACTTCTTTACCAATGTCTTTAGCAGCT
GATTAATAGCAACATACGATGTATTTGAAT	GCTTGAAATTTTCGTTGCGGTTTTGATGCTAAAATT
GATTAATAGCAACATACGATGTATTTGAAT	TTTTTTAAATTATTTAATTGTTCTTGAGCTGATTT
GATTAATAGCAACATACGATGTATTTGAAT	GTATCTAAGTTATCCAATATCCAAAATGCTAACTTT
GATTAATAGCAACATACGATGTTTTTGAAT	CCCAAATTTCCGTTTCCGCCTGCCCACGCTCGGCT
GATTAATAGCAACATACGATGTTTTTGAAT	TTTGGTATTGTGTAAGTATGTTGTGTTTTTAATAC
GATTAATAGCAACATACGATGTTTTTGAAT	TTTACGATTGCGCGGGCGTCTATAATAGTCTGCATTAC
GATTAATAGCAACATACGATGTATTTGAAT	TAAGTGTAAACATTTACAATTATGTTCAATTATGTG
GATTAATAGCAATATATGATATATTTGAAT	TCTATAACTATTTGTGTTAAAATCTTTTGACGTTGAA
GATTAATAGCAATATAAAATATATTTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027890855.1\|559766_560120_+\|50S-ribosomal-protein-L20	unknown	unknown	gnl\|CDD\|179959
NZ_LT906446.1\|WP_027890852.1\|553930_554695_+\|dihydroorotate-dehydrogenase-electron-transfer-subunit	unknown	unknown	gnl\|CDD\|99814
NZ_LT906446.1\|WP_027890848.1\|547140_547899_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NZ_LT906446.1\|WP_051177659.1\|560183_560630_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890846.1\|545291_545939_+\|translation-elongation-factor-Ts	unknown	unknown	gnl\|CDD\|183447
NZ_LT906446.1\|WP_087386221.1\|546106_546646_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NZ_LT906446.1\|WP_051177668.1\|558162_558510_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379090
NZ_LT906446.1\|WP_027890851.1\|550044_551697_-\|alpha,alpha-phosphotrehalase	unknown	unknown	gnl\|CDD\|274115
NZ_LT906446.1\|WP_027890849.1\|547981_548257_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NZ_LT906446.1\|WP_027890858.1\|562270_562531_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371058
NZ_LT906446.1\|WP_036254986.1\|546667_547093_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|366960
NZ_LT906446.1\|WP_051177658.1\|551750_553706_-\|PTS-system-trehalose-specific-EIIBC-component	unknown	unknown	gnl\|CDD\|273916
NZ_LT906446.1\|WP_008538462.1\|559530_559728_+\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NZ_LT906446.1\|WP_036254988.1\|565614_565932_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890857.1\|560795_562031_+\|LL-diaminopimelate-aminotransferase	unknown	unknown	gnl\|CDD\|181053
NZ_LT906446.1\|WP_027890853.1\|554695_555601_+\|dihydroorotate-dehydrogenase	unknown	unknown	gnl\|CDD\|235982
NZ_LT906446.1\|WP_027890850.1\|548467_549931_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|226465
NZ_LT906446.1\|WP_027890860.1\|563541_565248_-\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NZ_LT906446.1\|WP_051177660.1\|562752_563478_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NZ_LT906446.1\|WP_027890854.1\|558980_559544_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_027890855.1\|559766_560120_+\|50S-ribosomal-protein-L20	gnl\|CDD\|179959	PRK05185, rplT, 50S ribosomal protein L20; Provisional.	1.06523e-61
NZ_LT906446.1\|WP_027890852.1\|553930_554695_+\|dihydroorotate-dehydrogenase-electron-transfer-subunit	gnl\|CDD\|99814	cd06218, DHOD_e_trans, FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+. In L. lactis, DHOD B (encoded by pyrDa) is co-expressed with pyrK and both gene products are required for full activity, as well as 3 cofactors: FMN, FAD, and an [2Fe-2S] cluster.	1.17523e-108
NZ_LT906446.1\|WP_027890848.1\|547140_547899_-\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.11737e-79
NZ_LT906446.1\|WP_027890846.1\|545291_545939_+\|translation-elongation-factor-Ts	gnl\|CDD\|183447	PRK12332, tsf, elongation factor Ts; Reviewed.	4.39182e-125
NZ_LT906446.1\|WP_087386221.1\|546106_546646_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	1.90296e-33
NZ_LT906446.1\|WP_051177668.1\|558162_558510_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379090	pfam13248, zf-ribbon_3, zinc-ribbon domain. This family consists of a single zinc ribbon domain, ie half of a pair as in family DZR. pfam12773.	0.000450773
NZ_LT906446.1\|WP_027890851.1\|550044_551697_-\|alpha,alpha-phosphotrehalase	gnl\|CDD\|274115	TIGR02403, Trehalose-6-phosphate_hydrolase, alpha,alpha-phosphotrehalase. Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This family describes trehalose-6-phosphate hydrolase, product of the treC (or treA) gene, which is often found together with a trehalose uptake transporter and a trehalose operon repressor.	0
NZ_LT906446.1\|WP_027890849.1\|547981_548257_-\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	7.47847e-44
NZ_LT906446.1\|WP_027890858.1\|562270_562531_+\|hypothetical-protein	gnl\|CDD\|371058	pfam10446, DUF2457, Protein of unknown function (DUF2457). This is a family of uncharacterized proteins.	0.000547195
NZ_LT906446.1\|WP_036254986.1\|546667_547093_+\|HNH-endonuclease	gnl\|CDD\|366960	pfam02182, SAD_SRA, SAD/SRA domain. The domain goes by several names including SAD, SRA and YDG. It adopts a beta barrel, modified PUA-like, fold that is widely present in eukaryotic chromatin proteins and in bacteria. Versions of this domain are known to bind hemi-methylated CpG dinucleotides and also other 5mC containing dinucleotides. The domain binds DNA by flipping out the methylated cytosine base from the DNA double helix.The conserved tyrosine and aspartate residues and a glycine rich patch are critical for recognition of the flipped out base. Mammalian UHRF1 that contains this domain plays an important role in maintenance of methylation at CpG dinucleotides by recruiting DNMT1 to hemimethylated sites associated with replication forks. The SAD/SRA domain has been combined with other domains involved in the ubiquitin pathway on multiple occasions and such proteins link recognition of DNA methylation to chromatin-protein ubiquitination. The domain is also found in species that lack DNA methylation, such as certain apicomplexans, suggestive of other DNA-binding modes or functions. A highly derived and distinct version of the domain is also found in fungi where it is fused to AlkB-type 2OGFeDO domains. In bacteria, the domain is usually fused or associated with restriction endonucleases, many of which target methylated or hemi-methylated DNA.	0.0099598
NZ_LT906446.1\|WP_051177658.1\|551750_553706_-\|PTS-system-trehalose-specific-EIIBC-component	gnl\|CDD\|273916	TIGR01992, phosphotransferase_system_trehalose_permease, PTS system, trehalose-specific IIBC component. This model represents the fused enzyme II B and C components of the trehalose-specific PTS sugar transporter system. Trehalose is converted to trehalose-6-phosphate in the process of translocation into the cell. These transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci and Streptococci which contain their own A domain as a C-terminal fusion. This family is closely related to the sucrose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively). In E. coli, B. subtilis and P. fluorescens the presence of this gene is associated with the presence of trehalase which degrades T6P to glucose and glucose-6-P. Trehalose may also be transported (in Salmonella) via the mannose PTS or galactose permease systems, or (in Sinorhizobium, Thermococcus and Sulfolobus, for instance) by ABC transporters.	0
NZ_LT906446.1\|WP_008538462.1\|559530_559728_+\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	2.12353e-21
NZ_LT906446.1\|WP_027890857.1\|560795_562031_+\|LL-diaminopimelate-aminotransferase	gnl\|CDD\|181053	PRK07590, PRK07590, L,L-diaminopimelate aminotransferase; Validated.	0
NZ_LT906446.1\|WP_027890853.1\|554695_555601_+\|dihydroorotate-dehydrogenase	gnl\|CDD\|235982	PRK07259, PRK07259, dihydroorotate dehydrogenase.	6.80406e-176
NZ_LT906446.1\|WP_027890850.1\|548467_549931_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|226465	COG3956, COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only].	1.78305e-172
NZ_LT906446.1\|WP_027890860.1\|563541_565248_-\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NZ_LT906446.1\|WP_051177660.1\|562752_563478_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	7.21067e-58
NZ_LT906446.1\|WP_027890854.1\|558980_559544_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	3.43337e-90

>NZ_LT906446.1|WP_027890853.1|554695_555601_+|dihydroorotate-dehydrogenase
MNLAVKIGNLELKNPVMGASGTFGFGKEYEDFLDVNEIGAIVTKGVTPKPRAGNPGVRIAETPAGMLNCIGLENPGVDAFICDILPKIKKYNTAVIVNISASTVEEYAEMAWRLDIDGVDAVEVNISCPNVKEGGIVFGTDPKAAAAVTRAVKTHTSKTVIVKLSPNVTDITVMAKAVEEAGADAISMINTLTGMVIDINTRKPLLGNITGGLSGPAVKPVAVRMVWQVAKVVKIPIIGMGGITCAEDAIEFMLAGATAVAVGAYNFVDPSALKVVADGIADYMKKHNIEDVNELIGAVQA
>NZ_LT906446.1|WP_027890852.1|553930_554695_+|dihydroorotate-dehydrogenase-electron-transfer-subunit
MKKLVVVGKILVNEAINVNVKRMVIDAPQIADLAQPGQFVHVKKMDSVNFLRRPFSIADVNKDEGTITLIYRIVGKGTAEYSELKVGEQFNILGPIGNGFELKSGRPLLIGGGVGIAPLIYLARKLKDEKPILLIGGKNKDEVFWKDYLEEFADKIYITTDDGSVGFKGFTIQLLPQILAENKIEHIYTCGPNIMMEGVAKLAHEQDIDCQVSLEKRMACGIGVCLGCTFEGKLTKKRRKVCTEGPVFPSKEVF
>NZ_LT906446.1|WP_051177658.1|551750_553706_-|PTS-system-trehalose-specific-EIIBC-component
MAKFTKDATSLLEYVGGKDNIRAVTHCVTRMRFVLVDEKKADIKKIEALPSTKGTFTQAGQFQVIIGNEVSEYYNEFTKIAGIDGVSKDAVKNAAKSNQTFIQRLMSNLAEIFTPLIPALICGGLILGFRSVIGDIKLLDNGTKTLVENYQFFAGLYSFLWLIGEAIFHFLPVGIAWSITRKMGTTQILGIVLGLTLVSPQLLNAFAVVPGAQIPVWDFGIFQVEMIGYQSQVIPAILAAFILVYLEKFWRRVTPDYISMIVVPLMSLVPAVILAHVIVGPIGWAIGSFIANIVYAGLTSSFGWIFAGIFGFFYAPLVITGLHHMTNAIDLQLMSQFNGTILWPMVALSNIAQGSAVLAMIFLQRKNERAKQVNVPACISCYLGVTEPALFGVNLKYGFPLVCGLVGSCIAAMISVSSGVMASSIGVGGIPGILSIKPQYMFMFFIAMLEAICVPFILTTIVGKKKLSLEDIKGENSSISDNTPVQTTENKIETTLTDKSDIVSTFKSPVSGITKNLNEIEDKAFASGAMGEGFAVELTDGKVIAPFDGEVMVCFPTGHAYGLKSTDGTEILIHIGMDTVQLDGKGFDVKVEAGQKIKQGDVLVQVDLDYVKSQGKPLTTPIVFTDGSHIELLKKNSNISIGDDDIIKITK
>NZ_LT906446.1|WP_027890851.1|550044_551697_-|alpha,alpha-phosphotrehalase
MTDFQKKVVYEIYPKSFYDTTGNGTGDLKGVIAKLDYLQKLGVDYIWLTPFYLSPQNDNGYDIADYYSIDPSYGTMEDVELLIAEAKKRNIYLMFDMVFNHVSTESIWFKKALAGDSKYMNYFFFKDGKEGNKPPTNWQSKFGGSAWQYVKELDKWYLHLFDVTQADLNWENPDVREEVKNVVRFWMQKGVKGFRFDVINLISKSAFEDDFSSIGDGRQYYTDGPRIHEFLQELAQNSFAKDIDIITVGEMSSTTMENCYKYAGKNTGELTMVFNFHHLKVDFMGNEKWVLVPTDFMKLKHILFDWQINMTKHDAWNALFWCNHDQPRVVSRFGSDDKYHDVSAKMLATLIHLLRGTPYIYQGEEIGMTNPHFKSIEQYRDIESLNHYKILQDKGMTEKQALIILDIHSRDNARTPMQWNNTENAGFTTGTPWISPATNYTKINVENNLADENSIFYYYQKLIQLRKQLDVIAYGDIKPLLFEDNKVFAYERNYKETKLIVICNFYPINYEIELPYDLTGYKCLLNNYQIDIKNKKIALKPYETAVFCNL
>NZ_LT906446.1|WP_027890850.1|548467_549931_-|nucleoside-triphosphate-pyrophosphohydrolase
MGKITIIGLGPGNFGLITLDTWEKITSTDKLILRTAIHPTVAELDKRNVVYTACDDFYEKCASFEEVYNNIAEKLITEAKKGLNVVYAVPGSPLVAEKTVVIIRDKAKEANVELEIMPGMSFMEVLYQRLNIDPIDGLTILDAADLDNLPSEEMPSALVITQVYNQHVASDTKLTLMEHYPEDYPVTFIRNLSLPDEEIRQIPLYELDRQPNIDHLTSLYIGKMPKHEETFDLSPLEDVIQTLRSPGGCPWDIVQTHKSLRRNLIEEVYEVIEAIDLEDKDLLCEELGDLLMQVVFHARMAEEAGMFSMQDVIDGITEKLIRRHPHVFGDINVKDADEVLKNWEEIKRAEKKDRKSVLDGVPKDLPSLMAAYKLQHKASKVGFDWPDIDPVWDKLHEEVNELEEATVDSSTERIEEELGDVLFTIVNLARFLKIDPEIALTAANRKFKRRFSYIENKVKDKQQKWEQLTLLDLDDLWQEAKMLEENE
>NZ_LT906446.1|WP_027890849.1|547981_548257_-|HU-family-DNA-binding-protein
MNKSELVASVAEAAELTKKDAEKAVNAVFASVQKALVEDDKVQIIGFGTFEVRTRAARKGRNPQTGETIDIPESKNPVFKAGKALKDAVNQ
>NZ_LT906446.1|WP_027890848.1|547140_547899_-|SDR-family-oxidoreductase
MMKIALITGGTSGIGLATAKIFLENNICTVLVGRNKDKYIEARKFLKPYIKKDVFCDFIQSDITSASNCEKIINTVIEKYHGLDILINNAGIYKENAIENVSEAEFDEIMNTNIKGTYFLCKYAVSHLKKSQHNPAIVNVSSDAGINGNFFCSAYCASKGAVTIFTKALALELAPYNVRANCVCPGDIDTPLTRNQFAGNEEEGIKEAASLYPIGRIGKPEEVAEVIYFLANEKASFVTGAVWSVDGGITAC
>NZ_LT906446.1|WP_036254986.1|546667_547093_+|HNH-endonuclease
MKFVTSFKIGQVVSNNDIVSEFKVGNMGGMRRSLTTGTLVIIADHTKSLYDDKYYNQEIHYTGMGKYGDQVLKSQNRTLAESNTNGVEVHLFEVFEPKKYTYQGIVKLVDEPYQEVQKDENKIPRKVWIFPLKKIQYIEEK
>NZ_LT906446.1|WP_087386221.1|546106_546646_+|flavodoxin-family-protein
MFMKNVLIISTSPRKNGNTQTLCEQFEKGAKEQGHNVNLIRIMDKKIGFCRACGACIRNGGTCILKDDMAEIITLFQKADVVVFATPVYFYGVSAQMKTFIDRMYPIWQHLGSKEVYYIVAAGLGTDIIEKSLGDITGFVEHFEHYEIKGRLYAPNTMDAGKVKEQPVMEEAYNMGKNI
>NZ_LT906446.1|WP_027890846.1|545291_545939_+|translation-elongation-factor-Ts
MAITAALVKELREKTGAGMMDCKKALTATDGDMDKAIDFLREKGLASAAKKAGRVAAEGVVTSYIHAGGRIGVLVEVNCETDFVAGTDEFKDFARDIAMQIAAANPTCIRREEVDPAAVEHEKEVLREQALNEGKPEKIVERMVAGRLEKYYKEVCLLDQPYIKDPDVTISELVNSKIAKIGENISIRRFVRYQLGEGIEKKADNFVEEVMAAVK
>NZ_LT906446.1|WP_051177668.1|558162_558510_+|zinc-ribbon-domain-containing-protein
MLFFCLILGLIPALIASNKGRSFVLWYIYGFFLFIVALVHALCISKNDDALLKQDDSLKKCPYCAEIIKKEAIVCRYCGRDLPPVKEEKNNDNNDDDYEPSDYIKSIIASREKYK
>NZ_LT906446.1|WP_027890854.1|558980_559544_+|translation-initiation-factor-IF-3
MFPISKESLRVNGEIRAREVRVTDVKGAQLGIMSTRDALRKAEEAHLDLVEVAPKAKPPVCRIMDFGKYRYEQQKREKEAKKKQKVISVKEVKLRPGIETHDFNFKVKNALRFIAEGNKVKATIMFRGRELSHPEMGRELLLKVAEQMKDAVTVEREPKLEGKNMIMILAPKVQKAQTKGGKTNAKN
>NZ_LT906446.1|WP_008538462.1|559530_559728_+|50S-ribosomal-protein-L35
MPKIKTRRAAAKRFTATGSGEFKRNKAFKSHILEKKSPKRKRNLRKAAIITAADHKRVSKMLPYA
>NZ_LT906446.1|WP_027890855.1|559766_560120_+|50S-ribosomal-protein-L20
MPRVKSGVTAHARHKKILKLAKGYRGARSKQFKKANELVMKALYYARRDRRAKKGEFRRLWIARINAATRANGMSYSRFICGLTKAGVQVNRKMLADVAVNDAAAFAKLVEVAKNNL
>NZ_LT906446.1|WP_051177659.1|560183_560630_-|hypothetical-protein
MIKLFRRFAIFFAILALFAGYAMPISKTEAAPLFTVQSYWNGDTNYPLAFSQGTTNRYVDLSSAKLEEKTTDEAGITTAIFTFKVVMVNNNEMVNNYEYKTMIKVGGEELLIAAQRANNTSWSQITSTSFNQPQYNATLILADHFGIQ
>NZ_LT906446.1|WP_027890857.1|560795_562031_+|LL-diaminopimelate-aminotransferase
MALVNENYLKLQGSYLFAEVAHRVQKFKAENPSAEVISLGIGDVTLPLPQASIEAMHKAVDEMAHKETFRGYGPEQGYDFLREKIRDVIYKSRGVDIALDEIFVSDGAKSDCGNIQEIFGEDNTIAITDPVYPVYLDTNIMAGRTGLVKEDGTFEGVVYMPSTAENNFTPSLPTQHVDMIYLCCPNNPTGTTLSKEELAKWVQYAKENKSIILYDAAYSAYITEDDVPRTIYEVEGAKDVAIEFRSFSKTAGFTGTRCGYIVLPKTVMGYTKDGKAQALNPLWNRRHTTKFNGTAYVVQRAAEAVLTPEGQQQTKEMVGYYMENAKIIREGLASLGLTTFGGVNAPYIWLKVPAGMTSWDFFDKLLHEANIVGTPGSGFGPSGEGYFRLTAFGSRENTIKAVERIKTQLKL
>NZ_LT906446.1|WP_027890858.1|562270_562531_+|hypothetical-protein
MKKFLWCLLLVAVMFFPVSTNAFPLKTDVLNTEKNIIMYDDWDDDDDWRDDDRYEHDDDDWWDDDRYEHDDDDDWDDDWDDDRWDD
>NZ_LT906446.1|WP_051177660.1|562752_563478_+|alpha/beta-hydrolase
MDVNNLDKPLPVYFDIHGGGFVIGSLEQDDKLSRLISDTLNICVISMDYGLAPENPWPQGIEDVYDIVNYYVKNNDKYHIDTNNMAIGGHSAGGNIATVVAMMANETKEFSFKCQILDYPPIDLAKNPYTKPIIEGAIPPNVSVLYNSCYCTSEQSVNPHCSPIFASDAELSKLPPTVMLVCEIDSLCDEGIDYAMRLAHNGVEVTIKKFMGSRHGFTVHGTEDSKYGQQMIIDGLRNYLL
>NZ_LT906446.1|WP_027890860.1|563541_565248_-|proline--tRNA-ligase
MRTSKLYAPTLRQTPAEAEVPSHQLMLRAGFIRKVAGGVYTYLPLAWRTLRKIEQIIREEMDAKDGQELALPILQPAELWKETGRWEVFGEEMFRLVDRHNREFCLGPTHEEIITDLVRNEVRSYKQLPLLLYQIQNKYRDEIRPRFGLMRGREFIMKDGYSFDKDDAGLDKSYNDMYDAYTRIFNRCGLTFRPVEADGGAIGNATTHEFTVLAETGESDIVYCENCDYAANSEKSELKTIIPPAEEELPLEKVYTPHTKTIEAVAEYLNTPIEKNIKAVIFQNEKDQVICAFVRGDHEVNDVKLQNVTGAITLKMAEESAIRAIGGVPGFMSPIGLSKDAIVVVDPTVMEMHNAVCGANEEDHHYKNANPKRDFGDVIVADIRLIQAGDPCPHCGQPVKMTHGIEVGQVFKLGTKYSKALGATFLDENGKEKPLIMGCYGIGVSRTMAAAIEQFHDEHGIIWPAAIAPFEVVIVPISAKDAAQMEVAEKLYAQMKQAGIDVLLDDRKERAGVKFKDADLIGYPVRITVSPKLLDAQQVEIKVRKNGETINVNIDECSAKVKDMLQNL
>NZ_LT906446.1|WP_036254988.1|565614_565932_-|hypothetical-protein
MNKIQKLSLTLGTIFTVTISSTVGFAAEQTTTKVDMSRGDQIITPITARNIFDAKSNTKVDMHRNDQVITLVLATNIPDEKVNTKIDMQRNDQIITPVLATNIEE

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Crispr_ID: NZ_LT906446_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_2

658840-659594

Unclear

Consensus_repeat	Method
GTATTCGTACAAGAATTGTTATGGTTTATC	CRISPRCasFinder
GTATTCGTACAANNNTTGTTATGGTTTATC	CRT
GTATTCGTACAAGAATTGTTATGGTTTATC	PILER-CR
GTATTCGTACAAATTTTGTTATGGTTTATCTT	PILER-CR

11 spacers

cas6

The CRISPR arrays of NZ_LT906446_2

>merge|NZ_LT906446|2|658840-659594|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
AGTTATTTGCAAAAATTGTTAGGGTTTATCTTTTAGTGTTGAAGCGTTGTATCAACTTCAAATATAGTATTCGTACAAGAATTGTTATGGTTTATCTGGTTGCCCATAAATTTGGAAAAAGACATGACCATGGTATTCGTACAAGAATTGTTATGGTTTATCTTGTATTTGGTTCTACATTTGTTTTTGGATCTACGTATTCGTACAAGAATTGTTATGGTTTATCATGGAAATAACCCAAGATTTTCCCAAGTCATGCAAAGTATTCGTACAAGAATTGTTATGGTTTATCATTGATTAACAAAATAAGTGCTAATAAGTTTTTTAAGTATTCGTACAAGAATTGTTATGGTTTATCAGATAATTTTAAAAAGTTTTTAACAGAACTAAATACGTATTCGTACAAGAATTGTTATGGTTTATCATGTTGCATTTAACATCTCCCGTTTTTATTTGGCGGGTATTCGTACAAGAATTGTTATGGTTTATCTAGCTACCCTGAAGATTATAAATCATCTCATTTACAGTATTCGTACAAATTTTGTTATGGTTTATCTTATATTCAGGAAAAATATGTGTTATATACAGTTTAGTATTCGTACAAATTTTGTTATGGTTTATCTTATCAAAAAAATCAAAAAACTGGGGGGTTAATTGTATTCGTACAAATTTTGTTATGGTTTATCATAGAAAAGGATACCAGGTTTATTCGCAAATGGAAACGTATTCGTACAAATTTTGTTATGGTTTATCCT

>NZ_LT906446|2|2|658840-659592|CRISPRCasFinder
AGTTATTTGCAAAAATTGTTAGGGTTTATC	TTTTAGTGTTGAAGCGTTGTATCAACTTCAAATATA
GTATTCGTACAAGAATTGTTATGGTTTATC	TGGTTGCCCATAAATTTGGAAAAAGACATGACCATG
GTATTCGTACAAGAATTGTTATGGTTTATC	TTGTATTTGGTTCTACATTTGTTTTTGGATCTAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGGAAATAACCCAAGATTTTCCCAAGTCATGCAAA
GTATTCGTACAAGAATTGTTATGGTTTATC	ATTGATTAACAAAATAAGTGCTAATAAGTTTTTTAA
GTATTCGTACAAGAATTGTTATGGTTTATC	AGATAATTTTAAAAAGTTTTTAACAGAACTAAATAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGTTGCATTTAACATCTCCCGTTTTTATTTGGCGG
GTATTCGTACAAGAATTGTTATGGTTTATC	TAGCTACCCTGAAGATTATAAATCATCTCATTTACA
GTATTCGTACAAATTTTGTTATGGTTTATC	TTATATTCAGGAAAAATATGTGTTATATACAGTTTA
GTATTCGTACAAATTTTGTTATGGTTTATC	TTATCAAAAAAATCAAAAAACTGGGGGGTTAATT
GTATTCGTACAAATTTTGTTATGGTTTATC	ATAGAAAAGGATACCAGGTTTATTCGCAAATGGAAAC
GTATTCGTACAAATTTTGTTATGGTTTATC

>NZ_LT906446|2|2|658840-659592|CRT
AGTTATTTGCAAAAATTGTTAGGGTTTATC	TTTTAGTGTTGAAGCGTTGTATCAACTTCAAATATA
GTATTCGTACAAGAATTGTTATGGTTTATC	TGGTTGCCCATAAATTTGGAAAAAGACATGACCATG
GTATTCGTACAAGAATTGTTATGGTTTATC	TTGTATTTGGTTCTACATTTGTTTTTGGATCTAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGGAAATAACCCAAGATTTTCCCAAGTCATGCAAA
GTATTCGTACAAGAATTGTTATGGTTTATC	ATTGATTAACAAAATAAGTGCTAATAAGTTTTTTAA
GTATTCGTACAAGAATTGTTATGGTTTATC	AGATAATTTTAAAAAGTTTTTAACAGAACTAAATAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGTTGCATTTAACATCTCCCGTTTTTATTTGGCGG
GTATTCGTACAAGAATTGTTATGGTTTATC	TAGCTACCCTGAAGATTATAAATCATCTCATTTACA
GTATTCGTACAAATTTTGTTATGGTTTATC	TTATATTCAGGAAAAATATGTGTTATATACAGTTTA
GTATTCGTACAAATTTTGTTATGGTTTATC	TTATCAAAAAAATCAAAAAACTGGGGGGTTAATT
GTATTCGTACAAATTTTGTTATGGTTTATC	ATAGAAAAGGATACCAGGTTTATTCGCAAATGGAAAC
GTATTCGTACAAATTTTGTTATGGTTTATC

>NZ_LT906446|2|2|658906-659329|PILER-CR
GTATTCGTACAAGAATTGTTATGGTTTATC	TGGTTGCCCATAAATTTGGAAAAAGACATGACCATG
GTATTCGTACAAGAATTGTTATGGTTTATC	TTGTATTTGGTTCTACATTTGTTTTTGGATCTAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGGAAATAACCCAAGATTTTCCCAAGTCATGCAAA
GTATTCGTACAAGAATTGTTATGGTTTATC	ATTGATTAACAAAATAAGTGCTAATAAGTTTTTTAA
GTATTCGTACAAGAATTGTTATGGTTTATC	AGATAATTTTAAAAAGTTTTTAACAGAACTAAATAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGTTGCATTTAACATCTCCCGTTTTTATTTGGCGG
GTATTCGTACAAGAATTGTTATGGTTTATCTAGCTACCCTGAAGATTATAAATCATCTCATTTACAGTATTCGTACAAATTTTGTTATGGTTTATCTT	ATATTCAGGAAAAATATGTGTTATATACAGTTTA
GTATTCGTACAAATTTTGTTATGGTTTATCTT	ATCAAAAAAATCAAAAAACTGGGGGGTTAATT
GTATTCGTACAAATTTTGTTATGGTTTATCAT	AGAAAAGGATACCAGGTTTATTCGCAAATGGAAAC


>NZ_LT906446|2|3|659366-659594|PILER-CR
	TGGTTGCCCATAAATTTGGAAAAAGACATGACCATG
GTATTCGTACAAGAATTGTTATGGTTTATC	TTGTATTTGGTTCTACATTTGTTTTTGGATCTAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGGAAATAACCCAAGATTTTCCCAAGTCATGCAAA
GTATTCGTACAAGAATTGTTATGGTTTATC	ATTGATTAACAAAATAAGTGCTAATAAGTTTTTTAA
GTATTCGTACAAGAATTGTTATGGTTTATC	AGATAATTTTAAAAAGTTTTTAACAGAACTAAATAC
GTATTCGTACAAGAATTGTTATGGTTTATC	ATGTTGCATTTAACATCTCCCGTTTTTATTTGGCGG
GTATTCGTACAAGAATTGTTATGGTTTATCTAGCTACCCTGAAGATTATAAATCATCTCATTTACAGTATTCGTACAAATTTTGTTATGGTTTATCTT	ATATTCAGGAAAAATATGTGTTATATACAGTTTA
GTATTCGTACAAATTTTGTTATGGTTTATCTT	ATCAAAAAAATCAAAAAACTGGGGGGTTAATT
GTATTCGTACAAATTTTGTTATGGTTTATCAT	AGAAAAGGATACCAGGTTTATTCGCAAATGGAAAC
GTATTCGTACAAATTTTGTTATGGTTTATCCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027889679.1\|655861_657919_+\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NZ_LT906446.1\|WP_027889684.1\|665084_667340_+\|alpha-galactosidase	unknown	unknown	gnl\|CDD\|225882
NZ_LT906446.1\|WP_027889683.1\|663356_663557_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027889682.1\|660500_663089_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_LT906446.1\|WP_027889674.1\|651739_652639_+\|GTPase-Era	unknown	unknown	gnl\|CDD\|234624
NZ_LT906446.1\|WP_051177582.1\|663977_664400_+\|DUF2335-domain-containing-protein	unknown	unknown	gnl\|CDD\|370814
NZ_LT906446.1\|WP_027889681.1\|659800_660349_-\|flavodoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|378898
NZ_LT906446.1\|WP_027889685.1\|667428_668457_-\|DUF362-domain-containing-protein	unknown	unknown	gnl\|CDD\|225358
NZ_LT906446.1\|WP_155909547.1\|663804_663978_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027889675.1\|652684_653329_+\|DUF502-domain-containing-protein	unknown	unknown	gnl\|CDD\|225480
NZ_LT906446.1\|WP_027889686.1\|668509_670474_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NZ_LT906446.1\|WP_027889676.1\|653328_654093_+\|DNA-repair-protein-RecO	unknown	unknown	gnl\|CDD\|234622
NZ_LT906446.1\|WP_027889687.1\|670739_671381_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225851
NZ_LT906446.1\|WP_027889688.1\|671393_671882_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182513
NZ_LT906446.1\|WP_027889677.1\|654170_654707_+\|flavin-reductase	unknown	unknown	gnl\|CDD\|224766
NZ_LT906446.1\|WP_027889680.1\|658085_658778_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_LT906446.1\|WP_027889672.1\|650172_651174_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NZ_LT906446.1\|WP_027889673.1\|651198_651660_+\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|376735
NZ_LT906446.1\|WP_155909545.1\|649601_650024_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027889678.1\|654981_655860_+\|glycine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|236473

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_027889679.1\|655861_657919_+\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NZ_LT906446.1\|WP_027889682.1\|660500_663089_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_LT906446.1\|WP_027889674.1\|651739_652639_+\|GTPase-Era	gnl\|CDD\|234624	PRK00089, era, GTPase Era; Reviewed.	1.32607e-173
NZ_LT906446.1\|WP_027889681.1\|659800_660349_-\|flavodoxin-domain-containing-protein	gnl\|CDD\|378898	pfam12641, Flavodoxin_3, Flavodoxin domain. This family represents a flavodoxin domain.	1.03314e-49
NZ_LT906446.1\|WP_027889685.1\|667428_668457_-\|DUF362-domain-containing-protein	gnl\|CDD\|225358	COG2768, COG2768, Uncharacterized Fe-S center protein [General function prediction only].	2.12106e-48
NZ_LT906446.1\|WP_051177582.1\|663977_664400_+\|DUF2335-domain-containing-protein	gnl\|CDD\|370814	pfam10097, DUF2335, Predicted membrane protein (DUF2335). Members of this family of hypothetical bacterial proteins have no known function.	2.07261e-11
NZ_LT906446.1\|WP_027889675.1\|652684_653329_+\|DUF502-domain-containing-protein	gnl\|CDD\|225480	COG2928, COG2928, Uncharacterized conserved protein [Function unknown].	2.43572e-46
NZ_LT906446.1\|WP_027889686.1\|668509_670474_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	4.54739e-134
NZ_LT906446.1\|WP_027889676.1\|653328_654093_+\|DNA-repair-protein-RecO	gnl\|CDD\|234622	PRK00085, recO, DNA repair protein RecO; Reviewed.	1.66088e-45
NZ_LT906446.1\|WP_027889687.1\|670739_671381_+\|hypothetical-protein	gnl\|CDD\|225851	COG3314, COG3314, Uncharacterized protein conserved in bacteria [Function unknown].	7.80231e-24
NZ_LT906446.1\|WP_027889688.1\|671393_671882_+\|hypothetical-protein	gnl\|CDD\|182513	PRK10519, PRK10519, hypothetical protein; Provisional.	1.89881e-67
NZ_LT906446.1\|WP_027889677.1\|654170_654707_+\|flavin-reductase	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	1.86957e-16
NZ_LT906446.1\|WP_027889680.1\|658085_658778_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	4.19992e-11
NZ_LT906446.1\|WP_027889672.1\|650172_651174_+\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	2.74942e-133
NZ_LT906446.1\|WP_027889673.1\|651198_651660_+\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|376735	pfam02130, UPF0054, Uncharacterized protein family UPF0054.	2.13675e-57
NZ_LT906446.1\|WP_027889684.1\|665084_667340_+\|alpha-galactosidase	gnl\|CDD\|225882	COG3345, GalA, Alpha-galactosidase [Carbohydrate transport and metabolism].	0
NZ_LT906446.1\|WP_027889678.1\|654981_655860_+\|glycine--tRNA-ligase-subunit-alpha	gnl\|CDD\|236473	PRK09348, glyQ, glycyl-tRNA synthetase subunit alpha; Validated.	0

>NZ_LT906446.1|WP_027889680.1|658085_658778_+|CRISPR-associated-endoribonuclease-Cas6
MEVYQIRMKVYLLEDIPVNSVQTRITDFIDRAFLKKRELSVLHEVNTYKNYCYDLLYPVEADKIYKKGNIYTLTIRTIDKNMADFFQQICVNTYTRYIKGLNVDFRILPKKIIEFIYTLTPLIVKDERGYWRSVMSEEEFARRIRINLANKWNSFNNDNIDENFQLYTTMEFLNKVPISIEYKNVKLLGDKIRLSVADNEIAQKMAYMSLGTGLGEMNSRGAGFVNYRWL
>NZ_LT906446.1|WP_027889679.1|655861_657919_+|glycine--tRNA-ligase-subunit-beta
MAKDLLLEIGTEEVPAHFMPGILAQLKEKADAKFKEMRLEFEDITTLGTPRRTALLVKNLAEKQTGASSEYKGPSVAIAFDADGNPTKAAMGFARGKKIDVKDLVVKDGYVYAVSKEEGKDTAQLLPELLKNLIENLTFPKNMRWGDLDFRFVRPLRWIVALFDTDVMEFTVANVKSGRVSRGHRFLSDGDFTIAKASDYVADCEKASIIVDQNRRRDMIKEQIEKLAAQHNGHAEITEDLLEEVTYLVEYPTALCGSFEDKYLKLPKEAVITPMRDHQRYFPVLDDNNNLLPLFITVRNGGDYCLKTVQHGNERVLRARLADAQFFFDEDRKHKLEDYVEKLKTVVFQEGLGTIYDKANRLEELAAFIGEKTGANDVDIAVAKRAAKLAKADLVTAMVCEFTELQGIMGREYALLDGENPAVATAIYEHYMPRFAGDVEPSTTAGRLVSLADKMDNIVATFSRGLVPTGSQDPFALRRQALGIVYTMIEADYKIPLYEVADKAMDLLNITDEAKRAEIQKNLEDFFMLRLKNILSENNIRYDIIDAVLRHVGSIADAYAKACATAEEISSGKLNDAIQAFVRVNNISKKAENTTINPALFILDEEKALYETYGTVESKVHDAIVKVDYVKAIEEMQALTAPINNFFDNVMVMDKDEQIKNNRLALLKNIDNLVKTIADFSKIVL
>NZ_LT906446.1|WP_027889678.1|654981_655860_+|glycine--tRNA-ligase-subunit-alpha
MTFQEIILTLQKFWSEQGCILAQPYDVEKGAGTMNPSTFLRVLGPEPWHVAYVEPSRRPADGRYGENPNRLFQHHQFQVIMKPSPDNIQELYLQSLAKLGINEKEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEITQFTYFQQVGGVDVKPVSSEITYGLERIAMYIQEKENVYDIDWNGTYTYGDVFHQNEFEQSTYNFELADTTLLFDLFDKYEREAIRVIELGYVHPAYDYVLKCSHTFNLLDSRGAISVSERTAFISRVRNLARLCAQCYLKQREELGYPLLKKGAK
>NZ_LT906446.1|WP_027889677.1|654170_654707_+|flavin-reductase
MKKYVDVFDYAKEILQAIPKGVLLTTKAHGKVNTMAIGWGTLGIEWRKPIFIAFVRENRFTRFQLDENGEFTVNIPFKPFDKKILGYCGTHSGKDTDKIADLNLTLEEGEKISVPAIAELPLTLECKVIYKQKQDMKALSEELCKIHYPQDVDSSFSGSNKDSHIAYYGEIVSAYIIE
>NZ_LT906446.1|WP_027889676.1|653328_654093_+|DNA-repair-protein-RecO
MALYTTEVLVIGVKNWGNADKIVTLLSPEYGKITAAAYGCRRPKSPLASSMQLFSWLDVQLSRGERMDTIRQCEHKGFFAGLYEDLTAMAYGSFIAEFAKELCSEDEPQAEIYQTLLKILPCLTKNNPRICAVASAYQIFEYTGCQLHYDKCTLCGTKITGDAYFNPQQGGVLCDECSGHKAHNFSASLRAFITNMLLLDWDNPPKFQVKGADLVAAEQILLNYIQGLIGKPFKSLAFIKQVTQLNNMARNIKR
>NZ_LT906446.1|WP_027889675.1|652684_653329_+|DUF502-domain-containing-protein
MNRLSHYFINGLIVLVPIAITYIVIATIFSIIEGLVESYIPLKFPGAGIALLLVVILVAGWITSTCTWASEKIINYFESIVDKIPVVKFIYSSVKRVSTMLFESKTMFSQVVLIPYPSPGMKTIGFLMPKPSKVIAPYLSKDEEYESVFLPWSLNMTSGFNVFIPKKDIIFTDISVEDAFQYILTAGGVMPGADIKKDLAKIQEMSAQQNANKK
>NZ_LT906446.1|WP_027889674.1|651739_652639_+|GTPase-Era
MENKKFKSGFVAVIGRPNVGKSTLINSLIGQKIAIMSDKPQTTRNRIMCVLTTDNEQVIFLDTPGIHKPLHKLGEYMVKAAEGTLQEVDAILFVVDVTEDLGGGERYIMERLQATKKPVILIVNKLDLIDRQSVLPVIEKYTKAYPFAGVVPISAKEKLNLDSLLAELNKYLPEGPQYYPADTVTDQPERLIAAEMIREKVLHLTRDEVPHAIAVEVEEMKAQPNGKVDIRATIYVERESQKGIVIGKQGSLLKKIKTMARRDIETMLGSKTKLDLWVKVKKDWRDRSNVLREFGFKNP
>NZ_LT906446.1|WP_027889673.1|651198_651660_+|rRNA-maturation-RNase-YbeY
MEIILSSMPENLEIDVDIVDTVRRAAYKVGELYGLDNAEVSITFTDNEHIHEINREYRKVDRPTDVISFALNEGDEPEIEGGAPVNVLGDIIISVEKAVEQASDYGHSVEREVAFLTVHGMLHLLGYDHIEEEDRKEMRQEEDFVMEKLGISR
>NZ_LT906446.1|WP_027889672.1|650172_651174_+|PhoH-family-protein
MPNFAELKVSFQDRAETIGILGENDEYLRVLNDSFACRILGRDTNLSINGEEGEVNAAMQVIEALLLLYRQGTKLTMHEVRYSIKLVKAGQSNELKSLFTDILIVTSRGKCVRPKTIGQKIYVDAIRRHSITFGLGPAGTGKTYLAVVMAVMALRNHEVDKLILTRPAVEAGERLGFLPGDLQEKIDPYLRPLYDALQDILGLETYQKMLTRNIIEIAPLAYMRGRTLERAFVILDEAQNTTPRQMKMFLTRLGFGSKMVVNGDLSQIDLPRGGGSGLTQATKILDGLEGISVIQFDDRDVIRHDVVARIIRAYDAYEATHTEHKNNEKDNKN
>NZ_LT906446.1|WP_155909545.1|649601_650024_+|hypothetical-protein
MPPKVYKEDFPPEQEKNPTRGERPLDYMMARPKTQNVDKTEIYTEPEIVEEKISVEPKEDDVNNIYQEYLRKKEQQMHHKEVKDYIQNTEIKSTDEKKKVQIDIAHESIMNAIMYAQVLEMPKSVYYLKRYGIKRIIHKD
>NZ_LT906446.1|WP_027889681.1|659800_660349_-|flavodoxin-domain-containing-protein
MHKWLIVYSSLTGNTKQIAEAMYTTFTNGEADIFSIKEIDKINLDDYDYIAVGYWLTRGAPDKTVQEFLTTIKHKTVMLFQTHGTEPGSEHAVTAFARAAYKLGEDCTILGTFSSQGKINPALLARRQNNTDKNDPHAATERNKKRWESAAKHPDENDIQRAKDFIAAMKHKLALREKYLNK
>NZ_LT906446.1|WP_027889682.1|660500_663089_-|ATP-dependent-chaperone-ClpB
MGEEKYTQKVLEAMQSAQQEAALRYHQEITSAHVLAALIKEPEGLLATIFSECRVDLPMLKAKLEQMLKKIPSVKGQSRLGMSTEMVRVLGRAAKLAEDMKDEYISTEHLLLAIVSDSDDEMQSLCREFNLHQNKIMSVIKSERKQNVNSDNPESGYKSLEKYGRDLTAMARVGKLDPVIGRDEEIRRTVEILSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKNKTLYSLDMGSLIAGAKYRGEFEERLKSVLNEIAKSDGQILLFIDEIHTVVGAGAAEGAMDAGNLLKPMLARGELRCIGATTLNEYRKYIEKDTALERRFQPVMVDQPTVEDTISILRGLKERYEVHHGVRIRDNALVSAAVLSDRYISDRFLPDKAIDLVDEAAAKLRTEIESMPEPIEKLRRKIMQLQIEEEALNKETDAASKEKLDKLIEEKNKLQVEENTLMDKWNKEKQGIVRVRAIKKEMDSANTEMEKAQRNGDYAKASEIKYGKIPQLQKELSEMEKAVQDDEGNRLLKEEVSEEDIAQVVSRWTGIPVTKMLQGERDKLVHLEDVLHERVVGQDEAVKAVSEAIIRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAESLFDDERSMIRIDMSEYMEKHSVARLIGAPPGYVGYDEGGQLTEAVRRRPYSVILLDEIEKAHRDVFNVLLQILDDGRLTDGKGRVVNFKNTVIIMTSNLGSHEILNQSDFATAQKLVKDILKDYFRPEFLNRVDDIIVFKALDKQQVKQIASIMLNNLNKRLQRQINISLSWSDEALDKLANEGFDPNFGARPLRRLLSHTVETELSKEIIKGNVKDGDTVDIDVSGDDFTFNPIRKMED
>NZ_LT906446.1|WP_027889683.1|663356_663557_+|hypothetical-protein
MISDEMMTNDTLKPYFMKNKKWYYFDEENFCYKLTDRAPRKAIESYRKFYDDELIKINGEWHIIQK
>NZ_LT906446.1|WP_155909547.1|663804_663978_+|hypothetical-protein
MLKIQEMYLMIKQGFSSFLITPDTDYNSYISKDISKKAWQITGNRLKEAMVKIGGKY
>NZ_LT906446.1|WP_051177582.1|663977_664400_+|DUF2335-domain-containing-protein
MAKKNIPNSNHTQVELQQKNTELHAGIYQGPLPLPSIMEGYKNIDPSFPERIMKEFEKNSEHYRKGEEQAQKYAIERDIRGQWMAFILTLCLMAIIFFALYLGNMTFAGVGGLVFIVWIIRTFNVRVGKPTTNSKNQRNK
>NZ_LT906446.1|WP_027889684.1|665084_667340_+|alpha-galactosidase
MILFNEQAKTFHLKTAKTSYVMKVLDSGHLIHVYWGKSLHTNNLDYAVRRRDFFSFVANTDNIQEFHLEALAQEYPGYGSTDLRSPAIELVYGDGTSATDFRYLSHKITAGKPKLEGLPATYVESEDEAQTLEITLLDKVKNVEVVLSYSVFDKFDAIARSVKVVNKSDDTVKIQRVLSANVDFKDGNFEMIQLSGSWARERHIIRTPLRSGGQCVESRRGASSHAQNPFMALVRPETTENTGDAYAVSLIYSGNFLANTEVDMYNNSRLQIGINPFDFTWQLKAGESFQAPEAVLVYSGEGLTGMSHIYQNFYGKRLMRGYWRDKVRPVLINNWEATYFDFDEVKIKAIAKQASEFGIELFVLDDGWFGERNNDDRSLGDWVVNENKIHGGLKKLVDEVNAMGLKFGLWFEPEMVCPISKLYEAHPDWCLHIEGRTRSTARRQLILDLSRKEVCDYVIESVSSVLSSANIEYVKWDMNRNMTEIGSATLPPENQREVAHRYMLGLYRIMDEITSRFPKILFESCSGGGGRFDPGILYYMPQTWTSDDTDAMERLAIQYGTSMVYPSVSMGCHVSAVPNHQVHRITPFATRGICAMSGNFGYELDLTKLTEIEKMQAKSQVAFYKEVRELIQFGDFYRLQSPFGSNTCAWSFVAKDKSEAIVSFFRKMAEPNCAFATVYATGLDADAKYKDMRTGEVYGGDELMQVGINVPYAITSAPKATDDAKDMYAGMITDAIQGDYGAFIWHFKKVD
>NZ_LT906446.1|WP_027889685.1|667428_668457_-|DUF362-domain-containing-protein
MTSVSRRDFFKVAGSAVLGAAAYSITGTIPKASAQAPVIGSTQVTSANTVGSKAKVYFTKNIDADHLIKLYDLINEGIYGKVAIKLHTGEKNGPNIIPRNMAKAFWQHIPNSNIVETNTLYKGDRYTTEGHRETLKVNGWTFCPVDIMDENGTVMLPVRGGKHFKEVSMGKNIVNYDSMVVLTHFKGHAMGGYGGSMKNIAIGCADGRIGKSMVHGVPIDNQPADWGVWPGKETLMENMAESAKATIDYFGKHIVFLNVMRRMSVDCDCAGTAAAEPTIPDIGILASTDLLAIDQASIDLVYASPNNADLVERIESRHGLHQLTAMRDLKMGNDKYELITID
>NZ_LT906446.1|WP_027889686.1|668509_670474_-|sigma-54-interacting-transcriptional-regulator
MKKLVVISLGYNTGQTIYHQLCNLFSSILDIEYYFLSSPPPHNFEADLIVYSSNAAYQKMHKLADNHPYIIARRSINYHEINKLFKLPRYTEALLVNDTKESAEETILLLQTLGIDHINLSPYYPEIKNYPKLTIAITPGEIEHVPPCVNKIIDIKTRLVDITSLIEILTYFNMLEKFAHILSAKYIQDIIKLIKTGNKLLTDSSRMKERFKTVINNVHDGLIAINKENKVSVFNPIAEKLFNKKALNVIGQPIEEILDNKLLETVNNPRKEGILKLPSYEILISEMPLYAKNADRGRLYVLKDVSEIHRLEESVRRRLYEEQNIARYNFADIIGNSPALKKILSLAKKMAKTDATIFIQGESGTGKELLAQSIHNASSRRKGPFVAINFAALSETLLESELFGYEEGAFTGAKRGGSAGLFEIAHKGTLFLDEIGDAPLPFQVKLLRVLQEKQVRRVGGLKVIPIDVRIIVATNHNLKEDIKLKLFREDLYYRLNVLPLKIPALRERREDIMPLCYAFYKKYRPLSNDAKIYFKNIQPYLEAYNWQGNIRELQNVIEYLTSICPDDIPQSSDLPEDIKVQLFTDKSNTINLKEAIFLEIKRCNQNHEPVGRRSLANKFMLSENKIRDILLSLKIENKIMISPGKYGLKAIDLK
>NZ_LT906446.1|WP_027889687.1|670739_671381_+|hypothetical-protein
MEKPNKNDNIKIKVPWYGYVVFILAILLFSGIFSSSDGILRALDFNVLNGSFGQIPTDKAMSFRGAGGSGAKDGFLFALELIPAVILALGIVNVIDGLGGLKAAQKIMNPLLKPLLGVPGISALANIANMQSTDAAAGMVKELKDNGLITDKERSIIIAYQTSGSAFITNYFSSGAAAFSIMLAPIIVPIFVIFVFKIVGANLMRLYFKFLGQ
>NZ_LT906446.1|WP_027889688.1|671393_671882_+|hypothetical-protein
MSNVNNTEVKVNKNVLDLFIEGARKGFTIGTTSLLPNVVMAFVVIRILDVTGLLHLIGVVFEPVMGLWGLPGEAATVLITALMSMGGGVGVAMSLYTAGTLDATQITVLIPAIYLMGNPVQNVGRCLGIADVNTKHYPAIILICVINALLSIWAMRLIMMFL

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Crispr_ID: NZ_LT906446_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_3

733231-734840

Orphan

Consensus_repeat	Method
ATTCAAATACAACTCTTGTTAAGGTTAATC	PILER-CR
ATTCAAATACAACTCTTGTTAAGGTTAATC	CRISPRCasFinder
ATTCAAATACAACTCTTGTTAAGGTTAATC	CRT

24 spacers

The CRISPR arrays of NZ_LT906446_3

>merge|NZ_LT906446|3|733231-734840|PILER-CR,CRISPRCasFinder,CRT
ATTCAAAAACAACTCTTGCTAAGGTTAATTTTGTTTATATTATATACTACATTGCTTTAATTATGGATTTAAATACAACTCTTGTTAAAGTTAATCGTGAGCAGTCCAGTAGTTTTTTAATTCTTGAGTTAATTCAAATACAACTCTTGTTAAAGTTAATCGCGAACTTGGATAGTATCTATCTATCTTTTGCACTATATTCAAATACAACTCTTGTTAAGGTTAATCGGTGTTTATCGTTTCAATCCTTATTTGTTCGGAAAAATTCAAATACAACTCTTGTTAAGGTTAATCGTTGTATCAGTCAAAGAAATTAACATCTTGATGACATTCAAATACAACTCTTGTTAAGGTTAATCTTGGATGTTGCATAATTTATATTATTAATTCCCCATATTCAAATACAACTCTTGTTAAGGTTAATCAGGTTTCTAAATCTTCGGCAGCACAATTTTTAACAGATTCAAATACAACTCTTGTTAAGGTTAATCGCTTCGTTAACTTCTGCTTGTGTTGGCGTTTTTTGTATTCAAATACAACTCTTGTTAAGGTTAATCAAGAAAATCTTGTCGACCCTAACCTTGCTAAATACAATTCAAATACAACTCTTGTTAAGGTTAATCTTTATGGTTATGGTTCTAGCAGCACATTCAAGAAAAATTCAAATACAACTCTTGTTAAGGTTAATCAAATTTTGCAATGATTTATAAATTAGATTTAAACAAATTCAAATACAACTCTTGTTAAGGTTAATCCATGGTCTATGAATTTTTCTGAGTCTTTCCATTTCCATTCAAATACAACTCTTGTTAAGGTTAATCTAATCTACAGACAAACACCACTAACACAAGAAATAGATTCAAATACAACTCTTGTTAAGGTTAATCAATAAAAATGGATAATGAGTGGATAGAGAATTTGTAATTCAAATACAACTCTTGTTAAGGTTAATCACTAGCAAGTGTATTTGCACGATTAAGCAAAAATGAATTCAAATACAACTCTTGTTAAGGTTAATCAGAGGCAATTATTACTTATTATACTGCTGCTGATGAATTCAAATACAACTCTTGTTAAGGTTAATCTAATCAAGAAGATGTTAATATTGATAATGAGCCTCCATTCAAATACAACTCTTGTTAAGGTTAATCCCACCAGCTACAGAACGCAATTTCTTTATTTTAGGATTCAAATACAACTCTTGTTAAGGTTAATCAAATTCTAATAATAACGCTCTATCAATGTTTGCCTGATTCAAATACAACTCTTGTTAAGGTTAATCTCATATAGTTCTTCATTCTTATAAATCTTATCCAGATTCAAATACAACTCTTGTTAAGGTTAATCAAACTACCACCTACATTACCTATTACAGGAACAGCATTCAAATACAACTCTTGTTAAGGTTAATCTTTTTTCTTTTTCAGACGCAAACCAACAGCGAGATTAATTCAAATACAACTCTTGTTAAGGTTAATCTGATAGTATAGCTGCATAATGGGTGGTAATTATTAATTCAAATACAACTCTTGTTAAGGTTAATCAAACGCTGAAAAGGCTTCTACGGCTACAGAATTAATATTCAAATACAACTCTTGTTAAGGTTAATC

>NZ_LT906446|3|4|733231-734840|PILER-CR
ATTCAAAAACAACTCTTGCTAAGGTTAATT	TTGTTTATATTATATACTACATTGCTTTAATTATGG
ATTTAAATACAACTCTTGTTAAAGTTAATC	GTGAGCAGTCCAGTAGTTTTTTAATTCTTGAGTTA
ATTCAAATACAACTCTTGTTAAAGTTAATC	GCGAACTTGGATAGTATCTATCTATCTTTTGCACTAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	GGTGTTTATCGTTTCAATCCTTATTTGTTCGGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	GTTGTATCAGTCAAAGAAATTAACATCTTGATGAC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTGGATGTTGCATAATTTATATTATTAATTCCCCAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGGTTTCTAAATCTTCGGCAGCACAATTTTTAACAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	GCTTCGTTAACTTCTGCTTGTGTTGGCGTTTTTTGT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAGAAAATCTTGTCGACCCTAACCTTGCTAAATACA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTATGGTTATGGTTCTAGCAGCACATTCAAGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTTTGCAATGATTTATAAATTAGATTTAAACAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	CATGGTCTATGAATTTTTCTGAGTCTTTCCATTTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCTACAGACAAACACCACTAACACAAGAAATAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AATAAAAATGGATAATGAGTGGATAGAGAATTTGTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	ACTAGCAAGTGTATTTGCACGATTAAGCAAAAATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGAGGCAATTATTACTTATTATACTGCTGCTGATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCAAGAAGATGTTAATATTGATAATGAGCCTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	CCACCAGCTACAGAACGCAATTTCTTTATTTTAGG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTCTAATAATAACGCTCTATCAATGTTTGCCTG
ATTCAAATACAACTCTTGTTAAGGTTAATC	TCATATAGTTCTTCATTCTTATAAATCTTATCCAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACTACCACCTACATTACCTATTACAGGAACAGC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTTTTCTTTTTCAGACGCAAACCAACAGCGAGATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TGATAGTATAGCTGCATAATGGGTGGTAATTATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACGCTGAAAAGGCTTCTACGGCTACAGAATTAAT
ATTCAAATACAACTCTTGTTAAGGTTAATC

>NZ_LT906446|3|3|733231-734840|CRISPRCasFinder
ATTCAAAAACAACTCTTGCTAAGGTTAATT	TTGTTTATATTATATACTACATTGCTTTAATTATGG
ATTTAAATACAACTCTTGTTAAAGTTAATC	GTGAGCAGTCCAGTAGTTTTTTAATTCTTGAGTTA
ATTCAAATACAACTCTTGTTAAAGTTAATC	GCGAACTTGGATAGTATCTATCTATCTTTTGCACTAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	GGTGTTTATCGTTTCAATCCTTATTTGTTCGGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	GTTGTATCAGTCAAAGAAATTAACATCTTGATGAC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTGGATGTTGCATAATTTATATTATTAATTCCCCAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGGTTTCTAAATCTTCGGCAGCACAATTTTTAACAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	GCTTCGTTAACTTCTGCTTGTGTTGGCGTTTTTTGT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAGAAAATCTTGTCGACCCTAACCTTGCTAAATACA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTATGGTTATGGTTCTAGCAGCACATTCAAGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTTTGCAATGATTTATAAATTAGATTTAAACAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	CATGGTCTATGAATTTTTCTGAGTCTTTCCATTTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCTACAGACAAACACCACTAACACAAGAAATAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AATAAAAATGGATAATGAGTGGATAGAGAATTTGTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	ACTAGCAAGTGTATTTGCACGATTAAGCAAAAATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGAGGCAATTATTACTTATTATACTGCTGCTGATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCAAGAAGATGTTAATATTGATAATGAGCCTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	CCACCAGCTACAGAACGCAATTTCTTTATTTTAGG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTCTAATAATAACGCTCTATCAATGTTTGCCTG
ATTCAAATACAACTCTTGTTAAGGTTAATC	TCATATAGTTCTTCATTCTTATAAATCTTATCCAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACTACCACCTACATTACCTATTACAGGAACAGC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTTTTCTTTTTCAGACGCAAACCAACAGCGAGATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TGATAGTATAGCTGCATAATGGGTGGTAATTATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACGCTGAAAAGGCTTCTACGGCTACAGAATTAAT
ATTCAAATACAACTCTTGTTAAGGTTAATC

>NZ_LT906446|3|3|733231-734840|CRT
ATTCAAAAACAACTCTTGCTAAGGTTAATT	TTGTTTATATTATATACTACATTGCTTTAATTATGG
ATTTAAATACAACTCTTGTTAAAGTTAATC	GTGAGCAGTCCAGTAGTTTTTTAATTCTTGAGTTA
ATTCAAATACAACTCTTGTTAAAGTTAATC	GCGAACTTGGATAGTATCTATCTATCTTTTGCACTAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	GGTGTTTATCGTTTCAATCCTTATTTGTTCGGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	GTTGTATCAGTCAAAGAAATTAACATCTTGATGAC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTGGATGTTGCATAATTTATATTATTAATTCCCCAT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGGTTTCTAAATCTTCGGCAGCACAATTTTTAACAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	GCTTCGTTAACTTCTGCTTGTGTTGGCGTTTTTTGT
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAGAAAATCTTGTCGACCCTAACCTTGCTAAATACA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTATGGTTATGGTTCTAGCAGCACATTCAAGAAAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTTTGCAATGATTTATAAATTAGATTTAAACAA
ATTCAAATACAACTCTTGTTAAGGTTAATC	CATGGTCTATGAATTTTTCTGAGTCTTTCCATTTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCTACAGACAAACACCACTAACACAAGAAATAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AATAAAAATGGATAATGAGTGGATAGAGAATTTGTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	ACTAGCAAGTGTATTTGCACGATTAAGCAAAAATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AGAGGCAATTATTACTTATTATACTGCTGCTGATGA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TAATCAAGAAGATGTTAATATTGATAATGAGCCTCC
ATTCAAATACAACTCTTGTTAAGGTTAATC	CCACCAGCTACAGAACGCAATTTCTTTATTTTAGG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAATTCTAATAATAACGCTCTATCAATGTTTGCCTG
ATTCAAATACAACTCTTGTTAAGGTTAATC	TCATATAGTTCTTCATTCTTATAAATCTTATCCAG
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACTACCACCTACATTACCTATTACAGGAACAGC
ATTCAAATACAACTCTTGTTAAGGTTAATC	TTTTTTCTTTTTCAGACGCAAACCAACAGCGAGATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	TGATAGTATAGCTGCATAATGGGTGGTAATTATTA
ATTCAAATACAACTCTTGTTAAGGTTAATC	AAACGCTGAAAAGGCTTCTACGGCTACAGAATTAAT
ATTCAAATACAACTCTTGTTAAGGTTAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_157738444.1\|739558_740065_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225511
NZ_LT906446.1\|WP_027890910.1\|723817_724180_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890918.1\|732942_733164_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027889643.1\|746177_746570_+\|Asp23/Gls24-family-envelope-stress-response-protein	unknown	unknown	gnl\|CDD\|377129
NZ_LT906446.1\|WP_027890920.1\|735558_737562_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197216
NZ_LT906446.1\|WP_036255025.1\|737777_739475_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|377008
NZ_LT906446.1\|WP_027890919.1\|735059_735398_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027889645.1\|744183_744774_-\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|271355
NZ_LT906446.1\|WP_051177578.1\|741003_742149_-\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|274090
NZ_LT906446.1\|WP_027889646.1\|742250_744107_-\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|234715
NZ_LT906446.1\|WP_027890916.1\|730470_731625_-\|toxic-anion-resistance-protein	unknown	unknown	gnl\|CDD\|377557
NZ_LT906446.1\|WP_027889644.1\|744815_745841_-\|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NZ_LT906446.1\|WP_027890915.1\|728222_730280_-\|elongation-factor-G	unknown	unknown	gnl\|CDD\|237186
NZ_LT906446.1\|WP_027890911.1\|724387_725560_+\|trans-2-enoyl-CoA-reductase-family-protein	unknown	unknown	gnl\|CDD\|237460
NZ_LT906446.1\|WP_157738446.1\|740019_740913_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_LT906446.1\|WP_027890914.1\|727189_727999_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133409
NZ_LT906446.1\|WP_027890913.1\|726509_727052_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|226129
NZ_LT906446.1\|WP_027890917.1\|731644_732625_-\|NINE-protein	unknown	unknown	gnl\|CDD\|378398
NZ_LT906446.1\|WP_027890912.1\|725640_726450_+\|DUF805-domain-containing-protein	unknown	unknown	gnl\|CDD\|377540
NZ_LT906446.1\|WP_027890909.1\|723358_723802_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_157738444.1\|739558_740065_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.13015e-08
NZ_LT906446.1\|WP_027889643.1\|746177_746570_+\|Asp23/Gls24-family-envelope-stress-response-protein	gnl\|CDD\|377129	pfam03780, Asp23, Asp23 family, cell envelope-related function. The alkaline shock protein Asp23 was identified as an alkaline shock protein that was expressed in a sigmaB-dependent manner in Staphylococcus aureus. Following an alkaline shock Asp23 accumulates in the soluble protein fraction of the S. aureus cell. Asp23 is one of the most abundant proteins in the cytosolic protein fraction of stationary S. aureus cells, with a copy-number of >25000 per cell. A second Asp23-family protein, AmaP, which is encoded within the asp23-operon, is required to localize Asp23 to the cell membrane. The overall function for the family is thus a cell envelope-related one in Gram-positive bacteria.	1.53723e-42
NZ_LT906446.1\|WP_027890920.1\|735558_737562_-\|hypothetical-protein	gnl\|CDD\|197216	cd09117, PLDc_Bfil_DEXD_like, Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, and uncharacterized proteins with a DEAD domain. Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, uncharacterized type III restriction endonuclease Res subunit, and uncharacterized DNA/RNA helicase superfamily II members. Proteins in this family are found mainly in prokaryotes. They contain one copy of the conserved HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) in a single polypeptide chain, and have been classified as members of the phospholipase D (PLD, EC 3.1.4.4) superfamily. BfiI consists of two discrete domains with distinct functions: an N-terminal catalytic domain with non-specific nuclease activity and dimerization function that is more closely related to Nuc, an EDTA-resistant nuclease from the phospholipase D (PLD) superfamily; and a C-terminal domain that specifically recognizes its target sequences, 5'-ACTGGG-3'. BfiI forms a functionally active homodimer which has two DNA-binding surfaces located at the C-terminal domains but only one active site, located at the dimer interface between the two N-terminal catalytic domains that contain the two HKD motifs from both subunits. BfiI utilizes a single active site to cut both DNA strands, which represents a novel mechanism for the scission of double-stranded DNA. It uses a histidine residue from the HKD motif in one subunit as the nucleophile for the cleavage of the target phosphodiester bond in both of the anti-parallel DNA strands, while the symmetrically-related histidine residue from the HKD motif of the opposite subunit acts as the proton donor/acceptor during both strand-scission events.	0.000179936
NZ_LT906446.1\|WP_036255025.1\|737777_739475_+\|DUF262-domain-containing-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	6.95626e-29
NZ_LT906446.1\|WP_027890913.1\|726509_727052_-\|ECF-transporter-S-component	gnl\|CDD\|226129	COG3601, COG3601, Predicted membrane protein [Function unknown].	2.43425e-26
NZ_LT906446.1\|WP_027889645.1\|744183_744774_-\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|271355	cd00446, GrpE, nucleotide exchange factor GrpE. GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.	1.59116e-55
NZ_LT906446.1\|WP_027889646.1\|742250_744107_-\|molecular-chaperone-DnaK	gnl\|CDD\|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NZ_LT906446.1\|WP_027890916.1\|730470_731625_-\|toxic-anion-resistance-protein	gnl\|CDD\|377557	pfam05816, TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition.	3.15803e-135
NZ_LT906446.1\|WP_027889644.1\|744815_745841_-\|heat-inducible-transcription-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	1.10056e-119
NZ_LT906446.1\|WP_027890915.1\|728222_730280_-\|elongation-factor-G	gnl\|CDD\|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0
NZ_LT906446.1\|WP_027890911.1\|724387_725560_+\|trans-2-enoyl-CoA-reductase-family-protein	gnl\|CDD\|237460	PRK13656, PRK13656, enoyl-[acyl-carrier-protein] reductase FabV.	0
NZ_LT906446.1\|WP_027890914.1\|727189_727999_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133409	cd04782, HTH_BltR, Helix-Turn-Helix DNA binding domain of the BltR transcription regulator. Helix-turn-helix (HTH) multidrug-efflux transporter transcription regulator, BltR (BmrR-like transporter) of Bacillus subtilis, and related proteins; N-terminal domain. Blt, like Bmr, is a membrane protein which causes the efflux of a variety of toxic substances and antibiotics. These regulators are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the C-terminal domains are often unrelated and bind specific coactivator molecules. They share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	4.59175e-37
NZ_LT906446.1\|WP_051177578.1\|741003_742149_-\|molecular-chaperone-DnaJ	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	0
NZ_LT906446.1\|WP_027890917.1\|731644_732625_-\|NINE-protein	gnl\|CDD\|378398	pfam10112, Halogen_Hydrol, 5-bromo-4-chloroindolyl phosphate hydrolysis protein. Members of this family of prokaryotic proteins mediate the hydrolysis of 5-bromo-4-chloroindolyl phosphate bonds.	8.40211e-26
NZ_LT906446.1\|WP_027890912.1\|725640_726450_+\|DUF805-domain-containing-protein	gnl\|CDD\|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	9.88829e-16
NZ_LT906446.1\|WP_157738446.1\|740019_740913_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.53676e-56

>NZ_LT906446.1|WP_027890918.1|732942_733164_-|hypothetical-protein
MENVTDIRKVIMDICYQDGITRRKILATYNEKYNKKMLESVFNKMINSNNIKFNTLVDILDSIGYKIDIKKKI
>NZ_LT906446.1|WP_027890917.1|731644_732625_-|NINE-protein
MFTFISIIIVLFFVAAFAGFLTGLNILNDFLPLIAIAFGAGVVSYAIFKPKDKKLKLDLDDNDNNKMLEESFENALEDYNYIKSSTKYIKDTELKRLIQNMQKTAWNILTYLQKHPEKIPTARRFIDYYQDSAAGLLEKYIEIENTQLTTDNVREIKERTKETLYGLNNAYTEQFEKIINEQLLNMDAELKVMEQSIKADGYTTEKTTPKNSQDIPSIDNLDSFCGKRKGRHNMGFNQMKKHMSNVPQALFESSNTSILKRKLTAGALGIFFGSFGAHKFYLGKTFWGVLYLLFCWTGIPFIVGLVEGVRYIFMSQDEFFDKYISK
>NZ_LT906446.1|WP_027890916.1|730470_731625_-|toxic-anion-resistance-protein
MADISLDDLLKAKEREFNAQTQTQIQTVEPSKEIAKVTQQTELISPEDRKRIDEIKNAIDLTDSQASVQYGVNAQRNIAEFSDTILNNIRSKDSGYVGELLSNLVVKVKGFEVDGSSNGSFIKKIPILGSLVGKAQNMMAEYDKLSVQVDKIQAELDKARMVMLKDIVMFDTMYDKNVEYFKELQLYIRAGEEKIQELQTQTIPRLRQEAANLQNQMAVQLVSDFENAVSRFEKKVHDLKLSKTIAIQTAPQIRLIQNNDKVLVDKVQSAIFNTIPLWKSQIVIALGLSRQQKVLQMQREITNTTNELLRRNAEMLKQSTLETARETERGIVDIETVKKVNDDLISTIEETIKIQQEGRQKRKAAEAELVQIEDRLKQTLLAHR
>NZ_LT906446.1|WP_027890915.1|728222_730280_-|elongation-factor-G
MTEFNSIQLRNLALVGHGKSGKTLIAENCLFKSGTVNRVGKSEDGTSVLDYEPEEIKRKMTIDTSLASCQWQGYKINLLDTPGYPDFTGEVKSALMACEAAIVVVSAVSGVEVETDKAWQYAEELSLPRAIFINKMDREHADFNKVVEELRAKYGKGVVPIQLPIGSEDSFQGVADLITMNTKVLIKNKDLIYEIPEYMEEEVDEARHMLMETCAEFNDELLEKYLEGEEITETEVAAALIEGIVNARIFPVLCGSAAKGIGFRQLMNSIVEYMPTPYFRSSMGVNPKTNELIERNTEDAFSGYVFKTVVDQFIGRISYLKVLSGTLQENAMVYNSVCDKTERVANFYTACGKNQQAQKIAHAGDIVIVTKLQSTKTGDTLCDAQSPIRYEPVEFADSMFTMAIKADKKTDEDKIGNALNRLIDEDPTLKLEKNTETGDLLISGVGEAHLDIALEKLLNKFGVTAKLYKPEIAYRETIRGTSKVEGKHKKQSGGHGQYGDVWLEFSPGEQGSGVTFTETIVGGAVPRQYIPAVEKGVRETLQNGILAGYPMVDIKVNLYDGSYHTVDSSEMAFKTAAAIAIKKGVPEAKPVLLEPYCNLKITIPEYYMGDVISGINTKRGRILSTESPSHSVCIIEAQVPQAELYKYATDLRSATQGRGSYTMTFSHYEEVPAKISEKIVAERNK
>NZ_LT906446.1|WP_027890914.1|727189_727999_-|MerR-family-transcriptional-regulator
MSQTYFKTGEFAKLCNTTKDTLFHYDTIGLLKPAKVGENGYRYYSVNQAYLFDMISLLKEVGMNLIEIKNYMDKRNTTIFLNMLKEKDKKMREEIERLKRLRSLLKNTINITQNAFDVETDKISFVNREEEYFIVTPGEEKYTEKLVCEAIFNHINYCVKHNYSYTFMIGEIISKENIDNKTFKTTFYSTKIDKKVNSKQLHTKPAGKYAVKYVYGSYSDLIEKYMIFIDELTQSGYKVIGNIYEEDLLNYLSEADFNDYLMKIEVQIA
>NZ_LT906446.1|WP_027890913.1|726509_727052_-|ECF-transporter-S-component
MLTNKTRTLTGMGMLTALSLVLILLINFPILPAVPFMKYDPADIPILIGTFLFGTSGGLILTVLVSVIQGLFISGDGGPIGVLMHILATGSFVFVAGMIYQRTRTKMAALISLICGALTMTVVMVICNLIFTPLFLGAPMGKVVELLLPAIIPFNLIKAGVNAIITWFVYKPISRFIHNM
>NZ_LT906446.1|WP_027890912.1|725640_726450_+|DUF805-domain-containing-protein
MTLEQQFLSTAGRINRKIFVQYVFAFILLCILLAIPTILLNFTRSGFIVEIISSITFIIIELAMLPGIFLSVKRLHDLNKSALFVIYYILPLINIALLLYLIFFKGSAGDNKYGASPLDDDYDENFSENPLPKSLDMMDILEQKFFSTVGRVNRKPLILYLIFLIVCGIIGFSIYYVFFMVNPAALYMDIVSSGEILLMYYLFTAYIFITMPLRFLLIRRLHDLNLSGWWSILGIILPYGYIVLTIILIFIKGSIKENKYGKSPLVRDN
>NZ_LT906446.1|WP_027890911.1|724387_725560_+|trans-2-enoyl-CoA-reductase-family-protein
MIIKPRVKDFICLTSHPEGCKENVRRQIEYVKNQPKVDLGKRVLVIGASTGYGLASRICAAYGSGASTIGIIFDKPAHGKRTATAGWYNTAAFEEIAKADGLYAKTINGDAFSQEIKAKTIELIKKDFGQIDMIVYSLAAPRRTTADGTMYSSVLKTVDKPFTAKTLNLKTNEVTEATLPPATPEEVEATIKVMGGEDWADWMHALKDADVLAPNALSIAYSYIGSKITYPIYYEGTIGAAKQDLYKTAENLRKEGFNAVISVNKALVTQSSSAIPIVPLYVAVMYRVMKDKNVHEGTIQQMSRLWHEYLSKDNPVKDDEGRIRIDDLEMRDDVQETIFKYWDIVNNDNLKQYADVEGYWNDFYNLFGFGFDNVDYDADVNPDIEIDLVK
>NZ_LT906446.1|WP_027890910.1|723817_724180_+|hypothetical-protein
MHKGFYANRERTFAYLEKVYKYISILLKYLNDRYANGIKEAISYNIETNVNEYKKSCNKKVCSSTITEYHVISLSDLENIENPKPLLDRINTYIDMTNKVNSMITNKPSDFVERIIQHNK
>NZ_LT906446.1|WP_027890909.1|723358_723802_+|hypothetical-protein
MKKVMAPCVECFKETGIPNFNFVIQEQNDECVYSFKCDKGHEFILIQQIQRFELKFDMACFSYINDDYSAAVMHCASALERFREFFVQAVWLNNNCKENIALYEKYWKKVKSRSENQLGTFYVVYFSKFGDLDDVIEREVKFTQGDV
>NZ_LT906446.1|WP_027890919.1|735059_735398_-|hypothetical-protein
MPTIMTKYKYNDNLFLIYNTNLLNNNFSADELQCLSRDIQTDYIIIFNGGKINFYNAQGEEISADTDMNKIALYHQTKDVNIDITREIEVRFTDSYINRIMTSNNIFQSYIA
>NZ_LT906446.1|WP_027890920.1|735558_737562_-|hypothetical-protein
MAHRKTKQHTVNVITANFTAPTNISYLDLFEGYDELYAINFITNLDFLAEIMQFFTKIEIIFGNPSIIPTRLDTTFAMQRDALYELYKNEHYEQLAQRINDDSLKFFLADAPLYPEKLFCLKNKEGKTRVILGSSNFDQLPSNCDKNASIICFDDEVAYTYYIDLFEQFKNEHSYILDKTAAQTTFEDKQILENLPILHKAEADSEHIYQSAPKSTIVKMTEYMADIDRLAKDFVELPKADRKGQSRITFDKIDTIKTKTLDNMAARRAKFEKFMPQLVIEPDKERAFYNDREYNLHPLRADIKQDAELYLKYMEGFDTAVPSKNVQPLKFEYFKLMSWCFLSPFLARIRTTIREATVTDEVFTYPIVALLCGQSNAGKTIYASLLIKMMTDSSLYKAFGQSNFTKTRTDALLSDIKGLPILIDDITQTQFTNNSGNIIKQEERVIRENKPENLNYYPAMLLTANKDLNSLKNELTKRMVIFHVNASWNNEFTRQQKSPCSEIIKKMRNAFYSEYLRRIMPHINEYLSEITDIGSSTTDLYNTSSEVILSIFKDCRLDIPSYMRPLTMKDYFDSKAVNEIMIKFFQRQYRLNRDFFEINKKNNQLIFEDKSSSTVGKMTPMKIVESLPPELEADVVGDKIIMRLDSAINFFGINFKEQSLLGKLFNR
>NZ_LT906446.1|WP_036255025.1|737777_739475_+|DUF262-domain-containing-protein
MKAGEATLQKILNTSRQFIIPIFQRNFSWEKKQFKQLWTDIQRASKFTRERTHFIGSIVYIDMGTPAGRPQQLMLIDGQQRLTTLSLLLCALKRYVQKNDVETNLIKTKKIDNQFLLNSDEMGDDKYKLLLNAQDRETYIKLLEQTEFTVNTPSKRIMNCYEYFYQQIEKCADDLNSIFLGILNLSLVAISLDKDKDNPQLIFESMNSTGKDLAQSDLLRNYLLMDLSTREQNRLYTTYWKPMEDAFGQYAYLEKFDYFIRDFLTIKQNNGHICKVNDVYEQFKRYYIEQNLTKEDILKEIFIYAKYYAAIELDREKDKDLRMYWRQIRMIDCHVAYPFFLQLYHDYEQKNLAKEDFILIIKTTISYIVRRAICEIPTNSLNKTFAVFYNKINKQDYVNSVLKEYILKTAYRAFPTDYEVREKLQTKDIYHFRLKNYLLEMLENYYHKEPIDIVRDNYTIEHIMPQSPELNTTWQKMLGENWREVQKIYLHTLGNLTLTGYNSEMGNKSFEEKLNGENGFKHSHLKLNQYVASCEAWNKKSIQQRTSLLTDLILKIWSYPVFKNK
>NZ_LT906446.1|WP_157738444.1|739558_740065_+|helix-turn-helix-domain-containing-protein
MTKYSNEFKVKAIKMVLKGDSIYHVAKILNMPNTAPLRRWIFHYENGGISQLLHKNRKYTPIFKQKVIEYKWLHHLSLNQTAAKFSIPNTGTISTWEKLYSSYGFSGLLAKKRGRPSMKKSKNKVNKPKKELSYVEKLEQENYQLRMENDLLKKWHALMKQWEKEGRH
>NZ_LT906446.1|WP_157738446.1|740019_740913_+|IS3-family-transposase
MACLNEAMGKGRKTLVLVIAKLRKKYTLKALLNYTKLAKSTYYDALKKLSKEDKYKGLKTLIHNICNKNHGRYGYRRVTLQLHKQGIKVNHKVVMRLMKEENLTCKVRAKKYKSYRGQEGKIAKNILNRNFKAEKPNEKWATDVTEFALCNEKIYLSPIIDLYNGEIISYKISKRPILKQVLDMVKDATRKIKETKGIILHSDQGWQYQNRRYQELLKEKGIIQSMSRKGNCLDNAVIENFFGLLKSELFYLKKFKSVEDFIKELKSYIKYYNTKRIKIKLKGLSPVEYRTKSQLIA
>NZ_LT906446.1|WP_051177578.1|741003_742149_-|molecular-chaperone-DnaJ
MSTKRDYYEVLGVDKNASEAEIKKAFRKMVLKYHPDRNRDNPKEAEEKMKEVNEAYSVLSDPKKKAQYDQFGHAAFDGTAGAGAGGFDGFGGFSQGGGFDGFGDIFDMFFGSGGGPRGGARKRGPERGADLRYNLTITFEEAAFGKTETLNIPRTQQCPDCHGTGAAAGSHPETCPDCHGTGTVQSVQNTPFGRMVNQHPCSRCSGTGQIIKNPCKTCGGKGVKSIRSKVEVKIPAGVDTGNRIRVAGEGDAGVRGGSTGDLYVYITVKPDKFFQREGSEVICEMPITFVQAALGDTIEVPTLDGKVEMKIPAGIQSGTVMRLRGKGIPYLRSTGRGDQHVRIKVLTPQKLTERQKELLREFAGMTDDKTATGTGKTKKKQ
>NZ_LT906446.1|WP_027889646.1|742250_744107_-|molecular-chaperone-DnaK
MSKVIGIDLGTTNSVVAVMEGGEPTVITNPEGSRLTPSVVGFTKDGERLIGQLAKRQAVSNPDRTIASIKRHMGEVDYKVNIDGKSYTPPEISAMILQKLKGDAEKYLGETVTQAVITVPAYFNDSQRQATKDAGKIAGLDVLRIVNEPTAAALAYGLDKGENGTILVFDLGGGTFDVSILNLDDGMFQVVATNGNTHLGGDDFDNAVMNWMVEEFKKSNGIDLSQDKMAAQRLKEAAEKAKIELSSMTSTNINLPFITADATGPKHLDLTLTRAKFDELTADLVEATVEPTRKAMADAGLSASEIDKIILVGGSSRIPAVQEAIRKYFGKEPSHGVNPDECVAVGAAIQAGILSGELNDKNIVLLDVTPLSLGIETLGGICTRMIERNTAIPTSKSQVFSTAADNQPAVTIRVFQGEREMAADNKLLGTFELTDIPPAPRGVPQIQVTFDIDSNGIVHVSAKDLGTGKEQNITIKSDSGMSKEDIDRMVKEAQAHEAEDKKRKEAVETRNNADALVFQAEKTIKDLGDKADAGTVSKVKDGIEGVKTALKGNDTEAIKKAMEELQKPLYELSAAAYQQAQQAQQQAGGANAGAGAQQQSQPKDDGTVDAEFKDVTDK
>NZ_LT906446.1|WP_027889645.1|744183_744774_-|nucleotide-exchange-factor-GrpE
MTSPEENKNTVAKETEVNENVTDTTADNTDNDAKESPAEQATDDLEAIKKELEAQKALLQESEEHYKRLQADFMNFRRRNEKEREDLSSVILQGLIKDLLPIIDNFERALAVEEAKGSPLHDGISMVYNQLITSLQKNGLEEIKAVGEKFDPNFHQAVMRVEDPEKEDNTVEEVLQKGYMVQGRVIRPSMVKVVAN
>NZ_LT906446.1|WP_027889644.1|744815_745841_-|heat-inducible-transcription-repressor-HrcA
MLDERKQRILRAIVDDYISTAEPIGSRTIAKKYGLGISPATIRNEMADLETLGYIKHLHTSSGRIPSSKGYRFYVDDLLTLEQLSEDEKNLINHWYATKARSVEGIFRETSRIISQLTKNISLVLAPQLSQTAFRYLRFLPLDSSHVIAIIMTDAGFINNKVIAVPSGVTFKDFENIANVFNSYLKGRNLRDISMASIRKIRGETVNTTVFNAIINIIDEAMAQDKKNRLYLGGAGQLMEQPEFHNIDNVKRILSMLEQETLLCNILQEQRNKGLAVTIGQENKYNDIKDCSIISVTYHLDGKPVATLAVLGPTRMDYGKIISLLEFMNTNLADIFHRLHL
>NZ_LT906446.1|WP_027889643.1|746177_746570_+|Asp23/Gls24-family-envelope-stress-response-protein
MSETTKGTSNELGTIRIADEVVSIIAGLAATEVEGVAGMSGGIASGIAETLGRKNFSKGVKVEVGEKEAAVDLYIIVKYGSRIPDVALNVQESVKNAIENMTGLNTVEVNVHVQGVGFPEDVKEEEVRVR

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Crispr_ID: NZ_LT906446_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_4

1166382-1167862

TypeI-B

Consensus_repeat	Method
ATTCAAAAACAACNTTTGTTACTGTTAATC	CRT
ATTCAAAAACAACGTTTGTTACTGTTAATC	CRISPRCasFinder
ATTCAAAAACAACGTTTGTTACTGTTAATC	PILER-CR

22 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1,cas6

The CRISPR arrays of NZ_LT906446_4

>merge|NZ_LT906446|4|1166382-1167862|CRT,CRISPRCasFinder,PILER-CR
ATTTAAAAACAATATTTATTAATTTTAAACTGGTATAAATAATACCAGTTTATTTTTTATTCAAAAACAACTTTATTACTATTAATCGCAACTAGGCAGTAAAAATACTTATCAGGTTCGTTGGAGATTTAAAAACAACGTTTGTTACTATTAATCTAATTTTCATCAGTCATTAACATATCAAATATTAACAATTCAAAAACAACATTTGTTACTATTAATTTCTTATTCCAAGTTCCCAATTTCTTATGGTGTTCCTATTCAAAAACAACATTTGTTACTGTTAATCCCGATAAAACTATTATAAAAAATCACCCTCTTGTATTCAAAAACAACATTTGTTACTGTTAATCATTTTATATATATACATTATTAAATGCTCATATTTTATTCAAAAACAACATTTGTTACTGTTAATCGGTGCGCGGTGTTATTGGAATAATAAACTTTTCACCGTCATTCAAAAACAACATTTGTTACTGTTAATCAATTTTTATTGGCTAGATAAAACTAAATACTACCATATTCAAAAACAACATTTGTTACTGTTAATCGTCATCCACGAATTTTTCTTTACTCCATGTAATAGCATTCAAAAACAACGTTTGTTACTGTTAATCCGTTTTAAAATCCGCCAAAATTGCATTTAATATTTAATTCAAAAACAACGTTTGTTACTGTTAATCATAAACAGTATAAAATTAAAGAGAGGTGTTATTTCAATTCAAAAACAACGTTTGTTACTGTTAATCCTGTTTGACTTAAGCCGATGTCTTTTCTTAACTCCTATTCAAAAACAACGTTTGTTACTGTTAATCGCAAGTTTTGCCGAATTCAAAGCCACTTGATACAGCATTCAAAAACAACGTTTGTTACTGTTAATCTGTAGCATTGTGTTTCGTTCTTGTTCATTTAGTTCCATTCAAAAACAACGTTTGTTACTGTTAATCAGAAGCTATAGCCTATAAATATTATTATTTACATTCATATTCAAAAACAACGTTTGTTACTGTTAATCTACAAATGGAACAACAGGAAACATGATGAAGTTTATATTCAAAAACAACGTTTGTTACTGTTAATCTAATAAATAAAAAGTTTGGAAAACTAACAATACTCGAATTCAAAAACAACGTTTGTTACTGTTAATCTCAGCCACGAATGGCAGGTGCAGACTTGTATGCTCCATTCAAAAACAACGTTTGTTACTGTTAATCCGCAGTTACAAAAAATATGTTTAGAGATGAGCTTCATTCAAAAACAACGTTTGTTACTGTTAATCTATGCAAACAGTAATCGACACACAAGCGATTGTAAAATTCAAAAACAACGTTTGTTACTGTTAATCATAGAAAACAGTAAATTATTTATAACTGGAAGTTTTATATTCAAAAACAACGTTTGTTACTGTTAATCCAATCTATCGAATACCCATATATGCAAGCAAGCGTATTCAAAAACAACGTTTGTTACTGTTAATC

>NZ_LT906446|4|4|1166382-1167862|CRT
ATTTAAAAACAATATTTATTAATTTTAAAC	TGGTATAAATAATACCAGTTTATTTTT
TATTCAAAAACAACTTTATTACTATTAATC	GCAACTAGGCAGTAAAAATACTTATCAGGTTCGTTGGAG
ATTTAAAAACAACGTTTGTTACTATTAATC	TAATTTTCATCAGTCATTAACATATCAAATATTAACA
ATTCAAAAACAACATTTGTTACTATTAATT	TCTTATTCCAAGTTCCCAATTTCTTATGGTGTTCCT
ATTCAAAAACAACATTTGTTACTGTTAATC	CCGATAAAACTATTATAAAAAATCACCCTCTTGT
ATTCAAAAACAACATTTGTTACTGTTAATC	ATTTTATATATATACATTATTAAATGCTCATATTTT
ATTCAAAAACAACATTTGTTACTGTTAATC	GGTGCGCGGTGTTATTGGAATAATAAACTTTTCACCGTC
ATTCAAAAACAACATTTGTTACTGTTAATC	AATTTTTATTGGCTAGATAAAACTAAATACTACCAT
ATTCAAAAACAACATTTGTTACTGTTAATC	GTCATCCACGAATTTTTCTTTACTCCATGTAATAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGTTTTAAAATCCGCCAAAATTGCATTTAATATTTA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAAACAGTATAAAATTAAAGAGAGGTGTTATTTCA
ATTCAAAAACAACGTTTGTTACTGTTAATC	CTGTTTGACTTAAGCCGATGTCTTTTCTTAACTCCT
ATTCAAAAACAACGTTTGTTACTGTTAATC	GCAAGTTTTGCCGAATTCAAAGCCACTTGATACAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TGTAGCATTGTGTTTCGTTCTTGTTCATTTAGTTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	AGAAGCTATAGCCTATAAATATTATTATTTACATTCAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TACAAATGGAACAACAGGAAACATGATGAAGTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TAATAAATAAAAAGTTTGGAAAACTAACAATACTCGA
ATTCAAAAACAACGTTTGTTACTGTTAATC	TCAGCCACGAATGGCAGGTGCAGACTTGTATGCTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGCAGTTACAAAAAATATGTTTAGAGATGAGCTTC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TATGCAAACAGTAATCGACACACAAGCGATTGTAAA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAGAAAACAGTAAATTATTTATAACTGGAAGTTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	CAATCTATCGAATACCCATATATGCAAGCAAGCGT
ATTCAAAAACAACGTTTGTTACTGTTAATC

>NZ_LT906446|4|4|1166508-1167862|CRISPRCasFinder
ATTTAAAAACAACGTTTGTTACTATTAATC	TAATTTTCATCAGTCATTAACATATCAAATATTAACA
ATTCAAAAACAACATTTGTTACTATTAATT	TCTTATTCCAAGTTCCCAATTTCTTATGGTGTTCCT
ATTCAAAAACAACATTTGTTACTGTTAATC	CCGATAAAACTATTATAAAAAATCACCCTCTTGT
ATTCAAAAACAACATTTGTTACTGTTAATC	ATTTTATATATATACATTATTAAATGCTCATATTTT
ATTCAAAAACAACATTTGTTACTGTTAATC	GGTGCGCGGTGTTATTGGAATAATAAACTTTTCACCGTC
ATTCAAAAACAACATTTGTTACTGTTAATC	AATTTTTATTGGCTAGATAAAACTAAATACTACCAT
ATTCAAAAACAACATTTGTTACTGTTAATC	GTCATCCACGAATTTTTCTTTACTCCATGTAATAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGTTTTAAAATCCGCCAAAATTGCATTTAATATTTA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAAACAGTATAAAATTAAAGAGAGGTGTTATTTCA
ATTCAAAAACAACGTTTGTTACTGTTAATC	CTGTTTGACTTAAGCCGATGTCTTTTCTTAACTCCT
ATTCAAAAACAACGTTTGTTACTGTTAATC	GCAAGTTTTGCCGAATTCAAAGCCACTTGATACAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TGTAGCATTGTGTTTCGTTCTTGTTCATTTAGTTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	AGAAGCTATAGCCTATAAATATTATTATTTACATTCAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TACAAATGGAACAACAGGAAACATGATGAAGTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TAATAAATAAAAAGTTTGGAAAACTAACAATACTCGA
ATTCAAAAACAACGTTTGTTACTGTTAATC	TCAGCCACGAATGGCAGGTGCAGACTTGTATGCTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGCAGTTACAAAAAATATGTTTAGAGATGAGCTTC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TATGCAAACAGTAATCGACACACAAGCGATTGTAAA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAGAAAACAGTAAATTATTTATAACTGGAAGTTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	CAATCTATCGAATACCCATATATGCAAGCAAGCGT
ATTCAAAAACAACGTTTGTTACTGTTAATC

>NZ_LT906446|4|5|1166575-1167862|PILER-CR
ATTCAAAAACAACATTTGTTACTATTAATT	TCTTATTCCAAGTTCCCAATTTCTTATGGTGTTCCT
ATTCAAAAACAACATTTGTTACTGTTAATC	CCGATAAAACTATTATAAAAAATCACCCTCTTGT
ATTCAAAAACAACATTTGTTACTGTTAATC	ATTTTATATATATACATTATTAAATGCTCATATTTT
ATTCAAAAACAACATTTGTTACTGTTAATC	GGTGCGCGGTGTTATTGGAATAATAAACTTTTCACCGTC
ATTCAAAAACAACATTTGTTACTGTTAATC	AATTTTTATTGGCTAGATAAAACTAAATACTACCAT
ATTCAAAAACAACATTTGTTACTGTTAATC	GTCATCCACGAATTTTTCTTTACTCCATGTAATAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGTTTTAAAATCCGCCAAAATTGCATTTAATATTTA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAAACAGTATAAAATTAAAGAGAGGTGTTATTTCA
ATTCAAAAACAACGTTTGTTACTGTTAATC	CTGTTTGACTTAAGCCGATGTCTTTTCTTAACTCCT
ATTCAAAAACAACGTTTGTTACTGTTAATC	GCAAGTTTTGCCGAATTCAAAGCCACTTGATACAGC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TGTAGCATTGTGTTTCGTTCTTGTTCATTTAGTTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	AGAAGCTATAGCCTATAAATATTATTATTTACATTCAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TACAAATGGAACAACAGGAAACATGATGAAGTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	TAATAAATAAAAAGTTTGGAAAACTAACAATACTCGA
ATTCAAAAACAACGTTTGTTACTGTTAATC	TCAGCCACGAATGGCAGGTGCAGACTTGTATGCTCC
ATTCAAAAACAACGTTTGTTACTGTTAATC	CGCAGTTACAAAAAATATGTTTAGAGATGAGCTTC
ATTCAAAAACAACGTTTGTTACTGTTAATC	TATGCAAACAGTAATCGACACACAAGCGATTGTAAA
ATTCAAAAACAACGTTTGTTACTGTTAATC	ATAGAAAACAGTAAATTATTTATAACTGGAAGTTTTAT
ATTCAAAAACAACGTTTGTTACTGTTAATC	CAATCTATCGAATACCCATATATGCAAGCAAGCGT
ATTCAAAAACAACGTTTGTTACTGTTAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027889739.1\|1173431_1174433_-\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NZ_LT906446.1\|WP_027889753.1\|1158383_1159358_-\|phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl\|CDD\|234638
NZ_LT906446.1\|WP_027889743.1\|1168337_1169336_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NZ_LT906446.1\|WP_027889736.1\|1177504_1178758_-\|cytosine-deaminase	unknown	unknown	gnl\|CDD\|181713
NZ_LT906446.1\|WP_027889742.1\|1169362_1169854_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NZ_LT906446.1\|WP_027889748.1\|1163804_1164614_-\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213023
NZ_LT906446.1\|WP_027889744.1\|1168043_1168334_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_LT906446.1\|WP_027889750.1\|1162366_1162741_-\|cell-division-protein-FtsL	unknown	unknown	gnl\|CDD\|131264
NZ_LT906446.1\|WP_027889737.1\|1176334_1177027_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NZ_LT906446.1\|WP_027889741.1\|1169873_1172543_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|350688
NZ_LT906446.1\|WP_027889746.1\|1165592_1165796_+\|DUF1858-domain-containing-protein	unknown	unknown	gnl\|CDD\|274898
NZ_LT906446.1\|WP_027889749.1\|1162759_1163695_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NZ_LT906446.1\|WP_027889735.1\|1178790_1179549_-\|creatininase	unknown	unknown	gnl\|CDD\|275241
NZ_LT906446.1\|WP_027889745.1\|1165905_1166370_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239825
NZ_LT906446.1\|WP_027889752.1\|1159354_1160746_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl\|CDD\|223841
NZ_LT906446.1\|WP_027889738.1\|1174471_1176307_-\|hypothetical-protein	cas8b1	mkCas0106_cas8b1_CAS-I-B	gnl\|CDD\|188234
NZ_LT906446.1\|WP_027889747.1\|1164635_1165436_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|376615
NZ_LT906446.1\|WP_027889740.1\|1172609_1173428_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NZ_LT906446.1\|WP_027889751.1\|1160738_1162232_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|234660
NZ_LT906446.1\|WP_027889754.1\|1156871_1158236_-\|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	unknown	unknown	gnl\|CDD\|184511

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_027889739.1\|1173431_1174433_-\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	1.00328e-40
NZ_LT906446.1\|WP_027889753.1\|1158383_1159358_-\|phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl\|CDD\|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	3.2569e-142
NZ_LT906446.1\|WP_027889743.1\|1168337_1169336_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.56502e-150
NZ_LT906446.1\|WP_027889736.1\|1177504_1178758_-\|cytosine-deaminase	gnl\|CDD\|181713	PRK09230, PRK09230, cytosine deaminase; Provisional.	0
NZ_LT906446.1\|WP_027889742.1\|1169362_1169854_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.15158e-54
NZ_LT906446.1\|WP_027889748.1\|1163804_1164614_-\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.10902e-61
NZ_LT906446.1\|WP_027889744.1\|1168043_1168334_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.88196e-25
NZ_LT906446.1\|WP_027889750.1\|1162366_1162741_-\|cell-division-protein-FtsL	gnl\|CDD\|131264	TIGR02209, Cell_division_protein_FtsL, cell division protein FtsL. This model represents FtsL, both forms similar to that in E. coli and similar to that in B. subtilis. FtsL is one of the later proteins active in cell division septum formation. FtsL is small, low in complexity, and highly divergent. The scope of this model is broader than that of the pfam04999.3 for FtsL, as this one includes FtsL from Bacillus subtilis and related species. [Cellular processes, Cell division].	4.38523e-08
NZ_LT906446.1\|WP_027889737.1\|1176334_1177027_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.08759e-16
NZ_LT906446.1\|WP_027889741.1\|1169873_1172543_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	2.14862e-26
NZ_LT906446.1\|WP_027889746.1\|1165592_1165796_+\|DUF1858-domain-containing-protein	gnl\|CDD\|274898	TIGR03980, conserved_hypothetical_protein, hybrid cluster protein-associated redox disulfide domain. Members of this protein family resemble the domain of unknown function DUF1858 described by pfam08984, but all members contain an apparent redox-active disulfide. In at least one member protein, a cysteine in the CXXC motif is substituted by a selenocysteine. Most member proteins consist of this domain only, but a few members are fused to or adjacent to members of the hybrid-cluster (prismane) family or the nitrite/sulfite reductase family. [Energy metabolism, Electron transport].	2.14921e-26
NZ_LT906446.1\|WP_027889749.1\|1162759_1163695_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	1.63822e-173
NZ_LT906446.1\|WP_027889735.1\|1178790_1179549_-\|creatininase	gnl\|CDD\|275241	TIGR04448, creatininase, creatininase. Members of this family are creatininase (EC 3.5.2.10), an amidohydrolase that interconverts creatinine + H(2)O with creatine. It should not be confused with creatinase (EC 3.5.3.3), which hydrolyzes creatine to sarcosine plus urea. [Central intermediary metabolism, Nitrogen metabolism].	2.93709e-115
NZ_LT906446.1\|WP_027889745.1\|1165905_1166370_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	1.80349e-73
NZ_LT906446.1\|WP_027889752.1\|1159354_1160746_-\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl\|CDD\|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	3.94347e-145
NZ_LT906446.1\|WP_027889738.1\|1174471_1176307_-\|hypothetical-protein	gnl\|CDD\|188234	TIGR02591, cas_Csh1, CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI. This domain is found in the C-terminal 2/3 of a family of CRISPR associated proteins of the Hmari subtype. Except for the two sequences from halophilic archaea this domain contains a pair of CXXC motifs.	2.30809e-12
NZ_LT906446.1\|WP_027889747.1\|1164635_1165436_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|376615	pfam01790, LGT, Prolipoprotein diacylglyceryl transferase.	6.92069e-31
NZ_LT906446.1\|WP_027889740.1\|1172609_1173428_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.45941e-51
NZ_LT906446.1\|WP_027889751.1\|1160738_1162232_-\|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl\|CDD\|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
NZ_LT906446.1\|WP_027889754.1\|1156871_1158236_-\|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase	gnl\|CDD\|184511	PRK14106, murD, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional.	3.91819e-177

>NZ_LT906446.1|WP_027889745.1|1165905_1166370_+|YbaK/EbsC-family-protein
MSIDKVKAYFKQFNMEDKVMEFPTSSATVSEAAQTLNCEEARIAKTMSFKLNDTAILVVMAGDVRIDNHKFKEKFHKKATMLKGDEVETYTGFPIGGVCPFAPKDGVKVYLDISLKRFDIVYPACGSRNSAIKLTIPELEKYSKAIEWIDISKN
>NZ_LT906446.1|WP_027889746.1|1165592_1165796_+|DUF1858-domain-containing-protein
MTLTKDMGIMEVVSNYPETVEVFINAGMGCLGCAAAHFENIEQGATAHGIDVDQLMEDLNAVVNKEA
>NZ_LT906446.1|WP_027889747.1|1164635_1165436_-|prolipoprotein-diacylglyceryl-transferase
MDFIAFSWNSVNVYWYGIVMAVAVILGLAISWINVWLHKENFDIIIKIMVWGIPCSIVGARIVYVMQNMDYFSKNLSEIFCLWQGGLSIYGALLVFFAVCAICLKVNQMQILYWLDLIMPAIVFGLVILQITNFMMQFSVGTPLSVDIPNDHTPAEYIEYKYRPSGFEGYLYFQPVAFYQAAINFGIFILTVLLTLINRFFKLLSNGTIFLLALFLIALSRFYLGFMYLSVDKDVILYPVQWIALLVMIVTVIFYIGNKYRRAKRF
>NZ_LT906446.1|WP_027889748.1|1163804_1164614_-|polysaccharide-deacetylase-family-protein
MLKKSIWYKLILVVMVLCLPLLVSSPKIVPASAAENEDNISITVLNYHKIDDMNISLSVLPADFDRQMAYLKEHGYNTINSQQLYDYLSNGAELPPNPIMITFDDGYEDNYVNAYPILQKYGFTGTIFVITDFVSAQPNYLTWDQIKEMKAHGMDFQSHTATHQSMTGLSEDQLRTELVKSKQTLDQQLNQNTLFIAYPTGTYNLYIAKLVDEAGYKGAFTIKYGNIDKDSNIYALERVPIFHTENTFLSFYERMHYIPVFERLGWYKS
>NZ_LT906446.1|WP_027889749.1|1162759_1163695_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MEFEHISVLPNEVIEGLNIKPDGIYVDCTLGGAGHSSRIAERLSEKGHLIGIDQDDDAIKAATQRLSQYKCKIDIVHSNFKDLEQVLNDLNIEFVDGFLFDLGVSSYQLDEAERGFSYMHDAELDMRMDTTAKFSAYNVVNEYDEEKLNYIFKTYGEERWAKRIAQFIVQYRREKPIETTGQLVDIIRRAIPAAVRKKATGHPAKRIFQAIRIEVNNELGILEETFHTAVNHLNSGGRIAVITFHSLEDRITKNAFKEMARGCICPPHLPICVCHHKAQIKLCGKAIKPSMEEMEKNSRSKSAKLRIAERL
>NZ_LT906446.1|WP_027889750.1|1162366_1162741_-|cell-division-protein-FtsL
MLAQRKESEWENVQALPKKNKIRKTVKQRRQEKNLNNALRTRCMILFAITTIMAVFFILRSGVAASEAYQLNQMKRQATVLETENSRLHLEIAHLKSPERIQQIAQQELGMILPDKFFFSNTSN
>NZ_LT906446.1|WP_027889751.1|1160738_1162232_-|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MTIEQLVSVLKDVEVLGDTSKEIEFIAHDSRRVRKNTLFVCISGTRVDGNKFIPQAVDAGACAVMTEKDVTVPEGITVIKVKNIHKAMELCVPYFWGYPGKKMRMIGVTGTNGKTSSTYMLRDILRNAGYKVGVIGTIKIMIEDEELPIHNTTPDVIDLQETLAKMYEKGMDYVVMEVSSHALDMNRVAGCEYDTAIFTNLTQDHLDYHKTMENYALAKAKLFDSLSAPDLVKTGKTAVINIDDELGSKTMIEHTKCDLITYGIKHKDATLKAENVEIKASGASFEVEYNNEVMHFDLKVTGMFNVYNILGVIGAALAEHINPAIIKETLENFESVAGRFELVRQGQDFSVIVDYAHTPDGLENVLKTAREIAKKRLIVVFGCGGDRDRTKRPIMGRIAAQLADVVIATSDNPRTEDPEFILSEVEAGVLPALHGNFHEKITDRRHAIFRAIELAQKDDIVLIAGKGHENYQILKTGTIHFDDKEVAIEAIRGKLNG
>NZ_LT906446.1|WP_027889752.1|1159354_1160746_-|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MADFQFTLTQVMQVTNAVLKKITSASIFGGVTTDTRKVEEGMLFVALKGEKFDGHDFIAEAAKKGAIGAIVNKDYDVSRLEDVEIDILAVNDTLKAYQDLAKLWRSKFSIPVIGITGSNGKTTTKDLTAAVLSGKWNVLKTQANFNNEIGLPMTLLQLNKSYDVAVVEMGMRGLGQIKLLTDIAKPTIGVITNVGETHMELLGSIENIAKAKSEMAQAIEIDGKVVLNADDEHVAKMHEVTKARPIYFGINHAADVKAFNVKTVGEGKTEFDAFIGENMAHFTLNMLGIHNVYNCLAALAVGYACGLTIEEMQKGLASFKPTAMRFEYKKVGDFNVINDAYNASPMSTKAALSNLAKVTDGRKILVMGDMFELGSVEVKAHEDIAVQAKEAGVSIIVTRGTLTQNTARKAREIGIPEVYECANHEEAVATLKKVLQKDDTVLFKGSHGMHMEKIIELLENEYK
>NZ_LT906446.1|WP_027889753.1|1158383_1159358_-|phospho-N-acetylmuramoyl-pentapeptide--transferase
MMDIFNINMFGAAIAAALIVLVMGPFLIPELHKLKFGQSIREEGPKSHQVKSGTPTMGGIMIIAGITIATLIFADLTIEMGLALFVMLGHFVLGFLDDYIKVVLKRNLGLKAKQKFLGQLVIALIVTYIGVNYTGLTQDVWIPFIGKSYDIGWFYYVLVIGVLVGTTNAVNLTDGLDGLAAGSMAVASLGFVAVCLYFGKINLAIFSFACFGACVAFLKFNYHPAKVFMGDTGSLALGGVLAALGILTKTELLLIILGGLFVIETLSVIIQVTSFKTTGKRVFLMSPIHHHFELKGWSETRVVWSFWTAELVFCVLAMLTLHFS
>NZ_LT906446.1|WP_027889754.1|1156871_1158236_-|UDP-N-acetylmuramoyl-L-alanine--D-glutamate-ligase
MDLTGKKVIVVGAGISGFAAAKLAKKLGATVIMSDANENVDQKHDLKPLRDAGVEIVLGKQTEALFKDADLVIISPAVPRHIPIFEKVGQSVPIISEVEFAYKLAKAPIFAVTGTNGKTTTTMLLGELMKTIYGKNNVGVGGNIGTPLCEECYRIGEDGCIVAEISSYQMEASSEFTTKGAAILNVTPDHLARHKTMDVYQAEKEKVFAHHTKDDFLVLNYDDERTRSMAQRAKSTICFFSSSQELEEGAFVKDGQLVIRWHGMLHAICKVDEMQIKGAHNIENALAAVSLAFLAGGDTVKMAQVLKDFAPVEHRIEPVRTLNGVTYYNDSKATNPEAANKAIGTFEHIILIAGGDDKKTPLDEFYALVNEHVDKLILVGDATARFEAEALKHKYPAVNIYKAGYSMEKAVELAHDMAKAPQVVLLSPACASFDMYDGYEARGRDFKRIVNELK
>NZ_LT906446.1|WP_027889744.1|1168043_1168334_-|CRISPR-associated-endonuclease-Cas2
MRKKINYNYAFVFYDVNEKRVQKVFKICKKYLSHFQNSVFRGEITPSKLMKLKLELQKVIVDEEDFVCIIKLMNDDVFGEEFIGKKDVETGESLFL
>NZ_LT906446.1|WP_027889743.1|1168337_1169336_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MGNTKCITSMGELSRKDNSLYFKNDKRHSHIPVENIKEIYCFNEVSINSKLLDFLAQKNIIVHFFNYYGNYSGTFYPRKKYMSGKLLVKQVEKFNTDRLTVARAIVKGIGINIYEVLYHYYKHDKKEVKEILDWIKTQFYSAVNEVKSIPELMAFEGDLWLRFYSTFKYFLPEDFVMNKRVKRPPDNPINALISFGNTLLYTKTISAIYRTHLDQRISFLHEPLEGRFSLSLDISEVFKPAIVFKTIFDLVNNRKIRVEKHFERKVNYCILNEEGRNIFLEAFQKRMEMVMQHPKLKRKTSYHSMLKIDCYKLIKFITEDKEFVPYSLKAGY
>NZ_LT906446.1|WP_027889742.1|1169362_1169854_-|CRISPR-associated-protein-Cas4
MKVNGTLMNYYIHCPRQCYLFGNRINLEDNSEDVKIGKVLHEERAEDKNTEIALGNIKLDKLTKEYLIEVKKSDADVEACKWQLLLYLKILKDKGIVRKGKLEFIEKKKTPKKTMILELTPELEIILEKHVKAIDELLKCDEVPPVLDKSSCKKCAYYEYCYI
>NZ_LT906446.1|WP_027889741.1|1169873_1172543_-|CRISPR-associated-helicase/endonuclease-Cas3
MDYKILNDLIENVDKYKAHRKPKNEEEKDGEQIYETLLEHTRRTERCFNEFWKAKKCDDVLDRFCDVLWQDKVIKKKDIEEAKIILKEMIEAIPIFHDLGKINPNFQIEKMENKEIIKDKNFIGTKHSFISAILYLSYFRNNIMKKIKGRKIKGLLKEFILYHAYIIERHHSGINKINDFIGKINFKINNNSEQVIKELPISKLIEAITKSKIYLNDLSLEEGDTDIIIASFEDTKFMNKNGKQRNREQGIYICIYIRWLYSLLVASDYYATSEFMNNGSFNEVEDLNNVQDWINIYENTGLMESIRKYQNEIYPMSIENLNKATNINILRSEIFCEAEEQIKNNYQENIFYLEAPTGSGKSNTAMNLSFKLMSLNKDLCKIFWIYPFNTLVEQNLDTLENIFGKKENIISKIAVINSLTPIKLKHVDCKGNTISENDEADENSEKSVYRQFLLDRQFLNYPMILSTHVSLFNTIFGESQQNLFGFYQLINSVIVLDEIQSYKNSIWTEIICFLKPLAKLFNMKIIIMSATLPNLDRLSQGQSEAIFLLKDSNKFFKTDCFKNRVQLNYDLLDNQSDDKFVQLKEHLKQYLDKNKKILIEFIKKRTANDFWMNLVEDEYFAEKNIKIEYLSGDDSLAERKRILDEVKNTKKTIILIATQVIEAGVDLDMDIGYKNISKLDSEEQFIGRINRSCKRKGITYFFKIDDAKTIYKNDIRVDSEFTVEEENMREILINKNFGDYYNKILDVTKKNNKATFKDFLENIADLNYERIAKNMKLIDENKNIVQVYLARTIKDVNGNVINGKEIWQQYINLLKMRYSMDYAEWKVNMSIITSKMNYFIYQVNKANLELKEYNDKMGNIIYIEDGDKYFKKDKFNREMLQGVGGIDFI
>NZ_LT906446.1|WP_027889740.1|1172609_1173428_-|type-I-B-CRISPR-associated-protein-Cas5
MEILKFKLSGKSAFFKKPEVNTYCYFTYGNIHRVALLGILGAILGYKGYSQMQDILSNKKKKGKLEPSYPEFYEKLKDLKIAILPLNPKGVITKKIQIFNNSVGYASKEQGGNLIVKEQWLENPKWEICILLDCEEAIKIKEAIQNHKCEFYPYLGTNDHFADIKYLGVEEAKTIEDDMYRIDSFVFKDDVDILDLEKEELEDWKSQEKPMPKGNFKYEEALPYKINEITNNYEFQRFIYTGKLVELQEDRKVYRIQDKNKKEIEDKYIIFY
>NZ_LT906446.1|WP_027889739.1|1173431_1174433_-|type-I-CRISPR-associated-protein-Cas7
MNKRVYGILGISSIMGNWNADFSGYPKSTSDGNVFGSDKALKYPMKKMWDNEEQNVLYIKSLAFGEKGKDGSIGLTPRTLKERYELLFGEDDLKDVKKVLTNLMTAVDVKNFGATFAESGCNIAITGAVQIGQGFNKYIDTNAEEQDILSPFKDAKAKEKNEVKAKAKAKANNLSEDDIEVKDAQNSTLGTKITSNEAHYFYPFVINPLAYKELIELGVTEGYTEEDYQNFKRTALVSATAFATNSKVGCENEFAVFVETESNAYLPNLSEYVTFAKDEDKNIIDLKNLADILNDMSQQIKSVEIYYNPYTTKLINDDIKDAKHFNIITSKEV
>NZ_LT906446.1|WP_027889738.1|1174471_1176307_-|hypothetical-protein
MFEECLDVFKRELEDDSNLILDEYIPADGSYIIVDNNGKIKKYQDIKLDKKKRGTSEAVVKGSYFEEICFYDYHSKLISMNKPVDSKKVIHSNNYLAFAVKKESITSKLTEAIIDNYYDTLKNPLEKKYKKSKEASKIYQKFEEEYAPVNIKILEKCRSWIKQHIFSIDKLVQIDLGKKDYLKIFFEVFEVGEEDNKKNRELFIQEDNRYIFPNIYNSNDYNVEVEGKIQGIPDNNMGMNAKKPFLAIKTRKTPAGYLVDEKKAILQKQFFEYLMNLASSGKNNVYIDTKNYRIKAYSDQDERDDFDEMASGYYLRIQKGKELEIQVQDNLVDYQNRLKLNFEYIKFINIDRKEDKLPEFAKRYGIYYKRTNVGNLINEIFFSKCLRTNYFMDISAINVKDSTLKQNIIMYRNAIFDWVYKGIDNNFSIVEEKFALSLIKNSIQSDDKYKLRAKSQLNLHWSLKDYFFKTKGKQGGNTMVDTAIKVRENVKEKVLSKNEVTMPSNDEEYYYAVGQLLSYLIFKSRAGKKMQSMVNPVLNAKRDNVIKMRLFQLYKKYNYDISIYNYHMKNLYAMILGYKPKNKVNQEMILFGYLDENILLKSNAKNVSNEN
>NZ_LT906446.1|WP_027889737.1|1176334_1177027_-|CRISPR-associated-endoribonuclease-Cas6
MKIYQIRLKLFLLENVAANKIQEKITAFIDSGFKTDEKWLNFHEQNSYKNYCYDQLFPLEEDKLYKKEKIYTLTIRTVDLELAKYFKLVCVDNHTKEIKGLVAEIRVLPKKILETVYTITPVIVKTEDGYWKDAIKFTEFEQRLKVNLIKKWNAYHNEKIDEDFDLYTMIELKNKKPIAMEYKNIKLLGDKVQIQVADNKRAQDLWYFALGVGLGEMNSRGCGFLNYRWL
>NZ_LT906446.1|WP_027889736.1|1177504_1178758_-|cytosine-deaminase
MKTLFINVRLKDIKDLQSILVSDGKFERIGKIEVQEDYNVIDLKGNLVVPPYVDPHIHLDYVFTAKAEGATNKTGTLFEGIQRWSETKSKFTKENIKYRAKKAIKKEVLAGVQYIRTHVDVTNKNFEALEAILELKEELKDIVTIQIVSFPQEGMYAYKNGVELVEEGLKMGADCVGAIPHFEYAKEFGEKSIHKAVELALKYDRLIDVHCDETDDEQSRYVELLAALTYMEGIDKKTTASHTCSLGSANNAYVFRLMNLLCKTKMNFISCPTENIYLQGRQDTYPKRRGLTRVKELNDNHINVCFAQDSISDPWYPLGNGNMMNILDHGIHICQMMSFGEIDNALDLITINGAKTMNLDDVYGIEIGNDANFIVINAKSEFEAICERAGVLASIRNGKYLFDKIPEKVNTDIELLS
>NZ_LT906446.1|WP_027889735.1|1178790_1179549_-|creatininase
MYMSYYMHDLTWPEFNDKKDKVVILPIGSTEQHALHLPLCTDAKIAEQFSLHLAEKIDGVVMPTIVYGYKSKPLSGGGPLFPGTIDLNGSTLIYLVHDILMELVRDGFTKIFIMNAHFENEAFVVEAMDLVNRETNGAATIVESNWWDPMPEDVIDLIFDKVPFPGWALEHAAVTETSLMLYFAPQLCRMDRTVDVVSTNALPYFRYPLKKDDVPESGALASCAYSSAEKGKIIVDKVLPELVNICKKEFNI

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Crispr_ID: NZ_LT906446_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_5

2122280-2122627

Consensus_repeat	Method
GTTAAGCATTAACATTGTACGGTC	CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTCTC	CRT

5 spacers

The CRISPR arrays of NZ_LT906446_5

>merge|NZ_LT906446|5|2122280-2122627|CRISPRCasFinder,CRT
GTTAAGCATTAACATTGTACGGTCTCACTTAGTTGTTCCTAAAATAGAAACAGAAAAAATTACTGCGTTAAGCATTAACATTGTACGGTCTCACTTTAATATAGCGCTTCTTATTTTTACGCTCTCTATTAAGTTAAGCATTAACATTGTACGGTCTCACTTTTAGATATAGAAAAGCAGGATATGGATTTAACGAGTTAAGCATTAACATTGTACGGTCTCGCTAAGGCAAACAAACATATTAAGACACATAAAGTCTTGTTAAGCATTAACATTGTACGGTCGCCTTCTATTTTATCTTGATACTTTAATTGTGGCTTTAGTTAAGTATTAATATTGTACAATGTG

>NZ_LT906446|5|5|2122280-2122626|CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTC	TCACTTAGTTGTTCCTAAAATAGAAACAGAAAAAATTACTGC
GTTAAGCATTAACATTGTACGGTC	TCACTTTAATATAGCGCTTCTTATTTTTACGCTCTCTATTAA
GTTAAGCATTAACATTGTACGGTC	TCACTTTTAGATATAGAAAAGCAGGATATGGATTTAACGA
GTTAAGCATTAACATTGTACGGTC	TCGCTAAGGCAAACAAACATATTAAGACACATAAAGTCTT
GTTAAGCATTAACATTGTACGGTC	GCCTTCTATTTTATCTTGATACTTTAATTGTGGCTTTA
GTTAAGTATTAATATTGTACAATGT

>NZ_LT906446|5|5|2122280-2122627|CRT
GTTAAGCATTAACATTGTACGGTCTC	ACTTAGTTGTTCCTAAAATAGAAACAGAAAAAATTACTGC
GTTAAGCATTAACATTGTACGGTCTC	ACTTTAATATAGCGCTTCTTATTTTTACGCTCTCTATTAA
GTTAAGCATTAACATTGTACGGTCTC	ACTTTTAGATATAGAAAAGCAGGATATGGATTTAACGA
GTTAAGCATTAACATTGTACGGTCTC	GCTAAGGCAAACAAACATATTAAGACACATAAAGTCTT
GTTAAGCATTAACATTGTACGGTCGC	CTTCTATTTTATCTTGATACTTTAATTGTGGCTTTA
GTTAAGTATTAATATTGTACAATGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027890016.1\|2118729_2119053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377544
NZ_LT906446.1\|WP_027890670.1\|2127703_2127892_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_LT906446.1\|WP_027890688.1\|2126623_2127040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890672.1\|2129149_2129674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_157738459.1\|2125198_2125393_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890009.1\|2110923_2111763_-\|YitT-family-protein	unknown	unknown	gnl\|CDD\|224203
NZ_LT906446.1\|WP_155909598.1\|2124341_2124530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909594.1\|2125618_2125813_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LT906446.1\|WP_155909571.1\|2122885_2123074_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|273593
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|379857
NZ_LT906446.1\|WP_027890010.1\|2111910_2112261_-\|NirD/YgiW/YdeI-family-stress-tolerance-protein	unknown	unknown	gnl\|CDD\|225653
NZ_LT906446.1\|WP_027890011.1\|2112479_2113160_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LT906446.1\|WP_157738458.1\|2123922_2124117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655
NZ_LT906446.1\|WP_027890687.1\|2125928_2126447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378186

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.52784e-12
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	gnl\|CDD\|377544	pfam05673, DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function.	6.58855e-124
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	gnl\|CDD\|379857	pfam16548, FlgT_N, Flagellar assembly protein T, N-terminal domain. FlgT_N is the N-terminal domain of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N contributes to the construction of the H-ring structure, and adopts a two-layer alpha-beta sandwich architecture composed of a four-stranded anti-parallel beta-sheet and two alpha helices.	0.00453328
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.02258e-136
NZ_LT906446.1\|WP_027890011.1\|2112479_2113160_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.13366e-88
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	6.25628e-56
NZ_LT906446.1\|WP_027890010.1\|2111910_2112261_-\|NirD/YgiW/YdeI-family-stress-tolerance-protein	gnl\|CDD\|225653	COG3111, COG3111, Periplasmic protein with OB-fold [Function unknown].	1.34944e-18
NZ_LT906446.1\|WP_027890009.1\|2110923_2111763_-\|YitT-family-protein	gnl\|CDD\|224203	COG1284, COG1284, Uncharacterized conserved protein [Function unknown].	4.19721e-69
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.62647e-53
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.90064e-08

>NZ_LT906446.1|WP_027890018.1|2121013_2122123_+|LPP20-family-lipoprotein
MKKYVMIIVCLLCSLWWAVASAQSVNVSGHGMNYDEAERDALRNAIEQAVGTMVDSTALVKNGILLNDEIYKFSKGYITNYQVIDKRWLEDGLYEVNILADVDTNPNSKLMNELTRLGIINRQLRDPKIAVIIPEYHIRAKIPDPAGETAVINKLIEAGFSRIVYAEGMRDTIGKLDYLTNQDMQNIANNLNVDILVVGEAFSEGVGDVSKFIGNGRGRNTGILSCNARLEAKIFIAKTGQIISANGTYGKAADVTEFIAGKKALNNAGEKMGDYIVEKLLNYGSGNKQNIELKVITTDYNKVNMVNNALQNIRGVNSARVNSYDEGTATIDIKYSGTPQNIYNQLIQNINCNLKLQQITYNTLTIVVY
>NZ_LT906446.1|WP_027890017.1|2119203_2120925_+|hypothetical-protein
MVKNIVLFIMSLYRDDSIEKEYTDDSNLFKASCKHTNETALKYIAWKLNQEQQQIDEIYAFISEQVRETSLDKFKELIQDEYYKDKIIDVPLYNNGEMKGSFKSISEMFDKLQAYKEKNPDDTVVIHVDMTGGLRHASMLMLALIRMLKYIGMELGLVLYVNFNTAKIENASDIMDMFTLLGGAEEFNSFGSVNQIQNYFDKLNSKKLRTSSSALELLLEEMRDFSEAIKVCTNYKDMTNVLSLLNDSLKIYKRIIKSKSNRLSEQELFFAKLILVIEKTYADILPKDNKPSSVPAIIKWCAKRDFLQAAITFYTEWIPVYLIENKLVIIKDASIEEECRKNKAWSNWQVSFFKNYRMSQSSQIKLEDVEEYELTYSTVRGLIESDLSANKILGKVKDKNKKFSDFLKETIDFIKKTTRYRFYKAVVNLSNNSILKQILRESMPKNENDFEVYLTRRLIKENSNLEAVVLNSVKGIEKNRVREIFDLKEDKKLTTVEKSKERREMFKEMLEKNIIETKLPKERLLQFVEEYSNYVNDWRNQVSHANSLAASRESNFDIAQAIINSVNLIDEKF
>NZ_LT906446.1|WP_027890016.1|2118729_2119053_+|hypothetical-protein
MNKVSIKNNVYVVAKVSSKYKNKLDYYLIIPGRGYEYAFTKNYRKSCYIFCKSPILLNKVLYNRSHNIPLMVLKKYFHHNMSYLIDCLELDDFVLKRGAKNKYHKAA
>NZ_LT906446.1|WP_027890015.1|2117471_2118449_+|Gfo/Idh/MocA-family-oxidoreductase
MKIGIAGNGKIVREMIGAAKTVAGISIEAICSRAQSKAKAEKIAQECNISKVYTDYQKMLSDSDIDFIYVAVSNNVHYQYTKQALEAGKNVICEKPFTVKASETEELIQIAKDKHLFLFEAITVIYAPNYQYIKDNLKEIGTLHYVHANYAQYSSRYDKYLNKEVTPAFSPESAGGALYDLNIYNLHFIVGIFGMPKNIIYRANLGFNGIDTSGTALLDYDGFTVVCSAAKDSESVSGIVFQGEKGYMRLEGATNECALIRVNKKGETEKIVSKERYNHRMINEFIAFEQMFKQQDYKTCYENLDHSMMVMKVLEQARESGNLEF
>NZ_LT906446.1|WP_027890014.1|2116029_2117460_+|PLP-dependent-aminotransferase-family-protein
MNKNLIDFVSLNKQSKKPLYVQLYDEIAEKIKCKTLSAGYKLPPVRILAQQLNINNGTVVSAYRELEKNGYIFTRRGSGSYVAEQMNTISSEVDEKKDVLIDLAEEVNAENIPTDVINMSSVSLNPEMISMEIFQKAIDEILKRDKGYAFTYQDSKGYLPLRQSIVQSLAQKKINTTQQNVQIISGAQQGIDIVARALLKHGDIVFVESPTYPGAMAAFRSCGAKIIDIKLTKEGIDLADLENKLKLFKPRLIYVMPNVQNPTGISYSKYVRHRLMGLARYHDVYILEDDYIGGLYYSKNEMLPLKTYDTDDRVIYIRTLSKVFMPGLRLAYLIVPSDLAQRLLNVKYISDIATSGLTQRIFDYYLREGLWQKHLNSIRSIYKTKFDFILKMMKKYLPKDISYIKPTGGLSVWLNLPERLLADDVIENAKKQGVIISNGAPFFVRRAPHRQLRISFAVLSLAEIKTGIKILAEIMK
>NZ_LT906446.1|WP_027890013.1|2114730_2115963_+|ATP-binding-protein
MLDLHNLLVCHHLLDDKTIEDFNKLMGGASVNKGKLAAQFIEQAEKLGLSGNIIKVYILYMLAHKNNCVSYAVESSGGKIGTSLYKAFCHDIDILSKLLVLKPSIVLGCEYLDDYEPTVKNVSAAFKTLEENLLTAKTVEEKADAFIEYYRTYGSGDMADYRAFRWSNSDEELVGIKYFEAMSLDELIGYEQQKQQLNDNTLAFVEGKPANNVLLVGARGTGKSSGVKAVVNSFFDKGLRLVQLTKDQLIALPIIMERLRTYSSKKFIIFLDDLSFEEFEVEYKYLKSAIEGGASAKPENVLIYATSNRRHLIKESYKNRGVDDDDMHRNDTLNETISLSDRFGLIINYLSPNQQEYLDIVDGLLRQHGVVLDKEELRIKAGAWAQEHSGRSGRIAQQFVTYYLGQIYNK
>NZ_LT906446.1|WP_027890012.1|2113143_2114610_+|HAMP-domain-containing-protein
MLSKLKQYIKEHIHLRLRYMPISLKLAFIYSIMLSMILIITLSATLVGIHYVLYHEAEISITLSANFVEKKANEKGLEEIIKDVEKSSLIPGVVMRITDKDNNVIYDSMPMYISNDKVQNNLQLQTQSPSFGDYIRNALLPENLKFINFRHFWIFYTQRTIEKDDNVYTLHFLRTITAEKVFLEELSETILYVGLVGVLISIICGFLLSRKLLKPLSDITKKVKDIEIQDLNKRIEVPPTHDEIEELANTFNLMLERLQKGFEQQRQFVSDASHELRTPATVICGYSDMLARWGKDDPQTADECITAIHSEAINMQRLIEKLLFLARADQKRQVLHKESISMKPLIADIAKDTQLIAPQHSVTCSLNEDGYIFADPLCMRQMLRIFLDNSIKYTPDGGKIEISSHNDGNKMIVKISDNGIGIGKEEQKKIFERFYRVDAARTKNGVGGTGLGLSIAEWIAQAHDIEIKLDSELEKGTTITLFIPLDFG
>NZ_LT906446.1|WP_027890011.1|2112479_2113160_+|response-regulator-transcription-factor
MTKIFIVEDERRIARFLQMELEHEGFATASESNGLRAYERIIQEDYDLVLLDIMLPEMDGLTICKNVRKISDIPIIMLTAKDEISDKVTGLDIGADDYITKPFAIQELLARIRVALRKHNNTAKQEEAATFVFKNIIVYLDRHEVTVNGKLVELTKKEYDLLLYMLQNHDHVLSREQILQFIWGYEYMGDTNVVDVYIRYLRSKIDDEFKEKYIHTVRGIGYVIKT
>NZ_LT906446.1|WP_027890010.1|2111910_2112261_-|NirD/YgiW/YdeI-family-stress-tolerance-protein
MKKLLIAILSVLIICVVGSAAVFAARHNSGNIQPTTIAEIQKNSYDDQRVLIEGQFTKHVYDDIFTFQDNNGTEMNVEVDDDCWFNLELNVPVQILAEVDKDWHGMDLDVKGIKKL
>NZ_LT906446.1|WP_027890009.1|2110923_2111763_-|YitT-family-protein
MKKYFLQYSMIVIGALISAISCNLFLIPNHFLSGGITGIAIIFHYLFDLPIGIQNIVFNIPILYIAYHFFGKIYFINTILGTFLYSTFIDLTSFLTPLTPLHNNPMLSAIVAGVVSGIGFGLILRASANTGGADVVAALIRKLYSYNIGTMIFALNCLIVLCGLVLFSFEAAIYTLIYMYIMGEVDNRIVTGFNKRKSIMIVSDKSEEIAEHIMNELGRGVTFIEGEGGYTHTKKRILYVVITLTQLSKVKEIALKSDAKSFFIISNASEVNGKGFSYK
>NZ_LT906446.1|WP_155909571.1|2122885_2123074_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_157738458.1|2123922_2124117_+|hypothetical-protein
MKNKVNEIKTKICIPKGFFGGNCSNCIYWEEYNRNSDGRAYCSYYDDWYYPSERRGCFTYERNW
>NZ_LT906446.1|WP_155909598.1|2124341_2124530_+|hypothetical-protein
MKNKVNEIKTKICIPKGTLGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_157738459.1|2125198_2125393_+|hypothetical-protein
MKNKANEIKIKICIPKGFFGGNCSDCIHWEEYNRNSDGRAYCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_155909594.1|2125618_2125813_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSDCIHWEEYNRASDGRAHCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_027890687.1|2125928_2126447_+|hypothetical-protein
MEKTIITFVLLAMVTLVPAVGFASENSSKEIKHLNGVSWGESYHEFSEKYSIRPILEACEINLDKKINLYGQEMDTKAIAYFNNDRLFMMQYCFPEKLTDEEFDKVTKVITKELGEVVAEDKNKEIGKMIAWRNDDELVALNKEGIYYLGLSLFDTDNIFSLERMNVLSVKR
>NZ_LT906446.1|WP_027890688.1|2126623_2127040_+|hypothetical-protein
MRIKENIFKEIVESPAPPPEVGGIIGGKEDIITCYFADKGSKENCYDSYYPSTDLLNKQIDKWQDDGIDFYGIYHTHFAGDDGLSSSDRRYIVNIMQAMPSQIQYLYFPIVFKNNMLIYKAIRENNIVKIVQEDIEII
>NZ_LT906446.1|WP_027890670.1|2127703_2127892_+|hypothetical-protein
MKTWMKNFILSILAIIAVIIFHEQIWHGILYVLSFFLGLIIDFVSILVVIGVGMYIILDLLT
>NZ_LT906446.1|WP_027890671.1|2128052_2128934_+|hypothetical-protein
MKKYFAHFISLAVFVMILGTSLVSEAAMKTVAVGNFIDGTQSRYGKMICEQLQSSIQNGLVQNKNYTVVERSNLDQIFRELGLQNSGVVNSSSAIEIGNLSGADYTLMGKVVEAEINPYNNLAYEGLKAKVAVSVQIVDNETGQVLSSDMVSDTDSSATKNNLKKFIKSDLVPGHMSVNSDSLIYNAAEKVANKVLERMNKINPLVGMVVAVKPNEDTVTFDLGYEDGVKEGDIYTIYAEAEPIVHPVTGEILGVDEKYVGTVKVEEVRNNLSIAKIKDCEVTPMVKDKVKRK
>NZ_LT906446.1|WP_027890672.1|2129149_2129674_+|hypothetical-protein
MKKIIITFVLLAMVALVPAVSFASENSNNSGIKQLKDIAWGESYHDFSTKYSIKPLLETCEITLDEKVNLYGQEMDTRAVACFYNDRLFMIQYCFPEKLTDEEFDKLTEVMTKELGEVGAKNENSIIGEMKGWKNNDELIALNKEGIYYIDFNFLDTDELCSLEKIKSLNINNK

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Crispr_ID: NZ_LT906446_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_6

2123232-2123652

TypeIII

Consensus_repeat	Method
GTTAAGCATTAACATTGTACGGTC	CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTCTCGTCC	CRT

6 spacers

The CRISPR arrays of NZ_LT906446_6

>merge|NZ_LT906446|6|2123232-2123652|CRISPRCasFinder,CRT
GTTAAGCATTAACATTGTACGGTCTCGTCCGCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGAGTTAAGCATTAACATTGTACGGTCTCGTCCGCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGAGTTAAGCATTAACATTGTACGGTCTCGTCCAATGGAAAGTCAGCAGCAGATGTATCTGGGACTACGTTAAGCATTAACATTGTACGGTCTCGTCCGAAACATTTAAATGTAGCTATAAAATAGAAATTCTTGTTAAGCATTAACATTGTACGGTCTCGTCCGAACATCTAGAACCTTGATGGTAGTAGCTATGCATTTGAGTTAAGCATTAGCATTGTATGGTTTCGCGCCTTCTGGTAGCTTTGTTTTAACAAATACGCTAAGCATTAACAATGTATAATGT

>NZ_LT906446|6|6|2123232-2123652|CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTC	TCGTCCGCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGA
GTTAAGCATTAACATTGTACGGTC	TCGTCCGCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGA
GTTAAGCATTAACATTGTACGGTC	TCGTCCAATGGAAAGTCAGCAGCAGATGTATCTGGGACTAC
GTTAAGCATTAACATTGTACGGTC	TCGTCCGAAACATTTAAATGTAGCTATAAAATAGAAATTCTT
GTTAAGCATTAACATTGTACGGTC	TCGTCCGAACATCTAGAACCTTGATGGTAGTAGCTATGCATTTGA
GTTAAGCATTAGCATTGTATGGTT	TCGCGCCTTCTGGTAGCTTTGTTTTAACAAATAC
GCTAAGCATTAACAATGTATAATGT

>NZ_LT906446|6|6|2123232-2123599|CRT
GTTAAGCATTAACATTGTACGGTCTCGTCC	GCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGA
GTTAAGCATTAACATTGTACGGTCTCGTCC	GCGTTGGGTAAATAATAAGATAATCTTCAATAGTGTCGA
GTTAAGCATTAACATTGTACGGTCTCGTCC	AATGGAAAGTCAGCAGCAGATGTATCTGGGACTAC
GTTAAGCATTAACATTGTACGGTCTCGTCC	GAAACATTTAAATGTAGCTATAAAATAGAAATTCTT
GTTAAGCATTAACATTGTACGGTCTCGTCC	GAACATCTAGAACCTTGATGGTAGTAGCTATGCATTTGA
GTTAAGCATTAGCATTGTATGGTTTCGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027890016.1\|2118729_2119053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377544
NZ_LT906446.1\|WP_027890670.1\|2127703_2127892_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_LT906446.1\|WP_027890688.1\|2126623_2127040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890672.1\|2129149_2129674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_157738459.1\|2125198_2125393_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909598.1\|2124341_2124530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909594.1\|2125618_2125813_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LT906446.1\|WP_155909571.1\|2122885_2123074_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|273593
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|379857
NZ_LT906446.1\|WP_027890010.1\|2111910_2112261_-\|NirD/YgiW/YdeI-family-stress-tolerance-protein	unknown	unknown	gnl\|CDD\|225653
NZ_LT906446.1\|WP_027890011.1\|2112479_2113160_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LT906446.1\|WP_157738458.1\|2123922_2124117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|225563
NZ_LT906446.1\|WP_027890687.1\|2125928_2126447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378186

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	gnl\|CDD\|225563	COG3018, COG3018, Uncharacterized protein conserved in bacteria [Function unknown].	1.28161e-06
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	gnl\|CDD\|377544	pfam05673, DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function.	6.58855e-124
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	gnl\|CDD\|379857	pfam16548, FlgT_N, Flagellar assembly protein T, N-terminal domain. FlgT_N is the N-terminal domain of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N contributes to the construction of the H-ring structure, and adopts a two-layer alpha-beta sandwich architecture composed of a four-stranded anti-parallel beta-sheet and two alpha helices.	0.00453328
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.02258e-136
NZ_LT906446.1\|WP_027890011.1\|2112479_2113160_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.13366e-88
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	6.25628e-56
NZ_LT906446.1\|WP_027890010.1\|2111910_2112261_-\|NirD/YgiW/YdeI-family-stress-tolerance-protein	gnl\|CDD\|225653	COG3111, COG3111, Periplasmic protein with OB-fold [Function unknown].	1.34944e-18
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.52784e-12
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.62647e-53
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.90064e-08

>NZ_LT906446.1|WP_155909571.1|2122885_2123074_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_027890018.1|2121013_2122123_+|LPP20-family-lipoprotein
MKKYVMIIVCLLCSLWWAVASAQSVNVSGHGMNYDEAERDALRNAIEQAVGTMVDSTALVKNGILLNDEIYKFSKGYITNYQVIDKRWLEDGLYEVNILADVDTNPNSKLMNELTRLGIINRQLRDPKIAVIIPEYHIRAKIPDPAGETAVINKLIEAGFSRIVYAEGMRDTIGKLDYLTNQDMQNIANNLNVDILVVGEAFSEGVGDVSKFIGNGRGRNTGILSCNARLEAKIFIAKTGQIISANGTYGKAADVTEFIAGKKALNNAGEKMGDYIVEKLLNYGSGNKQNIELKVITTDYNKVNMVNNALQNIRGVNSARVNSYDEGTATIDIKYSGTPQNIYNQLIQNINCNLKLQQITYNTLTIVVY
>NZ_LT906446.1|WP_027890017.1|2119203_2120925_+|hypothetical-protein
MVKNIVLFIMSLYRDDSIEKEYTDDSNLFKASCKHTNETALKYIAWKLNQEQQQIDEIYAFISEQVRETSLDKFKELIQDEYYKDKIIDVPLYNNGEMKGSFKSISEMFDKLQAYKEKNPDDTVVIHVDMTGGLRHASMLMLALIRMLKYIGMELGLVLYVNFNTAKIENASDIMDMFTLLGGAEEFNSFGSVNQIQNYFDKLNSKKLRTSSSALELLLEEMRDFSEAIKVCTNYKDMTNVLSLLNDSLKIYKRIIKSKSNRLSEQELFFAKLILVIEKTYADILPKDNKPSSVPAIIKWCAKRDFLQAAITFYTEWIPVYLIENKLVIIKDASIEEECRKNKAWSNWQVSFFKNYRMSQSSQIKLEDVEEYELTYSTVRGLIESDLSANKILGKVKDKNKKFSDFLKETIDFIKKTTRYRFYKAVVNLSNNSILKQILRESMPKNENDFEVYLTRRLIKENSNLEAVVLNSVKGIEKNRVREIFDLKEDKKLTTVEKSKERREMFKEMLEKNIIETKLPKERLLQFVEEYSNYVNDWRNQVSHANSLAASRESNFDIAQAIINSVNLIDEKF
>NZ_LT906446.1|WP_027890016.1|2118729_2119053_+|hypothetical-protein
MNKVSIKNNVYVVAKVSSKYKNKLDYYLIIPGRGYEYAFTKNYRKSCYIFCKSPILLNKVLYNRSHNIPLMVLKKYFHHNMSYLIDCLELDDFVLKRGAKNKYHKAA
>NZ_LT906446.1|WP_027890015.1|2117471_2118449_+|Gfo/Idh/MocA-family-oxidoreductase
MKIGIAGNGKIVREMIGAAKTVAGISIEAICSRAQSKAKAEKIAQECNISKVYTDYQKMLSDSDIDFIYVAVSNNVHYQYTKQALEAGKNVICEKPFTVKASETEELIQIAKDKHLFLFEAITVIYAPNYQYIKDNLKEIGTLHYVHANYAQYSSRYDKYLNKEVTPAFSPESAGGALYDLNIYNLHFIVGIFGMPKNIIYRANLGFNGIDTSGTALLDYDGFTVVCSAAKDSESVSGIVFQGEKGYMRLEGATNECALIRVNKKGETEKIVSKERYNHRMINEFIAFEQMFKQQDYKTCYENLDHSMMVMKVLEQARESGNLEF
>NZ_LT906446.1|WP_027890014.1|2116029_2117460_+|PLP-dependent-aminotransferase-family-protein
MNKNLIDFVSLNKQSKKPLYVQLYDEIAEKIKCKTLSAGYKLPPVRILAQQLNINNGTVVSAYRELEKNGYIFTRRGSGSYVAEQMNTISSEVDEKKDVLIDLAEEVNAENIPTDVINMSSVSLNPEMISMEIFQKAIDEILKRDKGYAFTYQDSKGYLPLRQSIVQSLAQKKINTTQQNVQIISGAQQGIDIVARALLKHGDIVFVESPTYPGAMAAFRSCGAKIIDIKLTKEGIDLADLENKLKLFKPRLIYVMPNVQNPTGISYSKYVRHRLMGLARYHDVYILEDDYIGGLYYSKNEMLPLKTYDTDDRVIYIRTLSKVFMPGLRLAYLIVPSDLAQRLLNVKYISDIATSGLTQRIFDYYLREGLWQKHLNSIRSIYKTKFDFILKMMKKYLPKDISYIKPTGGLSVWLNLPERLLADDVIENAKKQGVIISNGAPFFVRRAPHRQLRISFAVLSLAEIKTGIKILAEIMK
>NZ_LT906446.1|WP_027890013.1|2114730_2115963_+|ATP-binding-protein
MLDLHNLLVCHHLLDDKTIEDFNKLMGGASVNKGKLAAQFIEQAEKLGLSGNIIKVYILYMLAHKNNCVSYAVESSGGKIGTSLYKAFCHDIDILSKLLVLKPSIVLGCEYLDDYEPTVKNVSAAFKTLEENLLTAKTVEEKADAFIEYYRTYGSGDMADYRAFRWSNSDEELVGIKYFEAMSLDELIGYEQQKQQLNDNTLAFVEGKPANNVLLVGARGTGKSSGVKAVVNSFFDKGLRLVQLTKDQLIALPIIMERLRTYSSKKFIIFLDDLSFEEFEVEYKYLKSAIEGGASAKPENVLIYATSNRRHLIKESYKNRGVDDDDMHRNDTLNETISLSDRFGLIINYLSPNQQEYLDIVDGLLRQHGVVLDKEELRIKAGAWAQEHSGRSGRIAQQFVTYYLGQIYNK
>NZ_LT906446.1|WP_027890012.1|2113143_2114610_+|HAMP-domain-containing-protein
MLSKLKQYIKEHIHLRLRYMPISLKLAFIYSIMLSMILIITLSATLVGIHYVLYHEAEISITLSANFVEKKANEKGLEEIIKDVEKSSLIPGVVMRITDKDNNVIYDSMPMYISNDKVQNNLQLQTQSPSFGDYIRNALLPENLKFINFRHFWIFYTQRTIEKDDNVYTLHFLRTITAEKVFLEELSETILYVGLVGVLISIICGFLLSRKLLKPLSDITKKVKDIEIQDLNKRIEVPPTHDEIEELANTFNLMLERLQKGFEQQRQFVSDASHELRTPATVICGYSDMLARWGKDDPQTADECITAIHSEAINMQRLIEKLLFLARADQKRQVLHKESISMKPLIADIAKDTQLIAPQHSVTCSLNEDGYIFADPLCMRQMLRIFLDNSIKYTPDGGKIEISSHNDGNKMIVKISDNGIGIGKEEQKKIFERFYRVDAARTKNGVGGTGLGLSIAEWIAQAHDIEIKLDSELEKGTTITLFIPLDFG
>NZ_LT906446.1|WP_027890011.1|2112479_2113160_+|response-regulator-transcription-factor
MTKIFIVEDERRIARFLQMELEHEGFATASESNGLRAYERIIQEDYDLVLLDIMLPEMDGLTICKNVRKISDIPIIMLTAKDEISDKVTGLDIGADDYITKPFAIQELLARIRVALRKHNNTAKQEEAATFVFKNIIVYLDRHEVTVNGKLVELTKKEYDLLLYMLQNHDHVLSREQILQFIWGYEYMGDTNVVDVYIRYLRSKIDDEFKEKYIHTVRGIGYVIKT
>NZ_LT906446.1|WP_027890010.1|2111910_2112261_-|NirD/YgiW/YdeI-family-stress-tolerance-protein
MKKLLIAILSVLIICVVGSAAVFAARHNSGNIQPTTIAEIQKNSYDDQRVLIEGQFTKHVYDDIFTFQDNNGTEMNVEVDDDCWFNLELNVPVQILAEVDKDWHGMDLDVKGIKKL
>NZ_LT906446.1|WP_157738458.1|2123922_2124117_+|hypothetical-protein
MKNKVNEIKTKICIPKGFFGGNCSNCIYWEEYNRNSDGRAYCSYYDDWYYPSERRGCFTYERNW
>NZ_LT906446.1|WP_155909598.1|2124341_2124530_+|hypothetical-protein
MKNKVNEIKTKICIPKGTLGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_157738459.1|2125198_2125393_+|hypothetical-protein
MKNKANEIKIKICIPKGFFGGNCSDCIHWEEYNRNSDGRAYCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_155909594.1|2125618_2125813_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSDCIHWEEYNRASDGRAHCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_027890687.1|2125928_2126447_+|hypothetical-protein
MEKTIITFVLLAMVTLVPAVGFASENSSKEIKHLNGVSWGESYHEFSEKYSIRPILEACEINLDKKINLYGQEMDTKAIAYFNNDRLFMMQYCFPEKLTDEEFDKVTKVITKELGEVVAEDKNKEIGKMIAWRNDDELVALNKEGIYYLGLSLFDTDNIFSLERMNVLSVKR
>NZ_LT906446.1|WP_027890688.1|2126623_2127040_+|hypothetical-protein
MRIKENIFKEIVESPAPPPEVGGIIGGKEDIITCYFADKGSKENCYDSYYPSTDLLNKQIDKWQDDGIDFYGIYHTHFAGDDGLSSSDRRYIVNIMQAMPSQIQYLYFPIVFKNNMLIYKAIRENNIVKIVQEDIEII
>NZ_LT906446.1|WP_027890670.1|2127703_2127892_+|hypothetical-protein
MKTWMKNFILSILAIIAVIIFHEQIWHGILYVLSFFLGLIIDFVSILVVIGVGMYIILDLLT
>NZ_LT906446.1|WP_027890671.1|2128052_2128934_+|hypothetical-protein
MKKYFAHFISLAVFVMILGTSLVSEAAMKTVAVGNFIDGTQSRYGKMICEQLQSSIQNGLVQNKNYTVVERSNLDQIFRELGLQNSGVVNSSSAIEIGNLSGADYTLMGKVVEAEINPYNNLAYEGLKAKVAVSVQIVDNETGQVLSSDMVSDTDSSATKNNLKKFIKSDLVPGHMSVNSDSLIYNAAEKVANKVLERMNKINPLVGMVVAVKPNEDTVTFDLGYEDGVKEGDIYTIYAEAEPIVHPVTGEILGVDEKYVGTVKVEEVRNNLSIAKIKDCEVTPMVKDKVKRK
>NZ_LT906446.1|WP_027890672.1|2129149_2129674_+|hypothetical-protein
MKKIIITFVLLAMVALVPAVSFASENSNNSGIKQLKDIAWGESYHDFSTKYSIKPLLETCEITLDEKVNLYGQEMDTRAVACFYNDRLFMIQYCFPEKLTDEEFDKLTEVMTKELGEVGAKNENSIIGEMKGWKNNDELIALNKEGIYYIDFNFLDTDELCSLEKIKSLNINNK
>NZ_LT906446.1|WP_036254934.1|2129784_2130669_+|LPP20-family-lipoprotein
MKKTLIVLTSAALFSFGASILPVNTYFAPVKAEAQYQNPAYAQTETITADGYGVLPPNKPFGQAKLMARRAAVVEAQRNLLETVKDVAIDSETNVEMSMTLNDTIHSKVSGVIRGARVVDEEYIREDGIYRVTMSVPMYGDGSLGQVVFDNVIGNNQKVPVPAPSPTYNPNTSQINGNYTGLVIRARGAGLVRTFCPAIYDTSGRAIYGVYNVDKKYAIDYGVVGYAKGQQGWDTVRMGTSRAGSNPLVVDIVEVRQRVANKCDVVISVEDADRILAENRHSHFLDNYAVMFEI

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Crispr_ID: NZ_LT906446_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_7

2124692-2124926

TypeIII

Consensus_repeat	Method
TGTTAAGCATTAACATTGTACGGTCTCG	PILER-CR
GTTAAGCATTAACATTGTACGGTC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NZ_LT906446_7

>merge|NZ_LT906446|7|2124692-2124926|PILER-CR,CRISPRCasFinder
AGTTAAGCATTAACATTGTACGGTCTCGCGTTTGATAATTAAATGTTTGATAATTAATTATAGAAAAACCATGATAAACCTGTTAAGTATTAACATTGTACGGTCTCGTGTTTGAATCAGATTGCCTTTTACATAAATGGCACTATATTAAGCATTAACATTGTACGGTCTCACATGAGTTAAGTCACTTGTTTTAGATGGACTTATTATAGTTAAGTATTAATATTGTACAATG

>NZ_LT906446|7|6|2124692-2124864|PILER-CR
AGTTAAGCATTAACATTGTACGGTCTCG	CGTTTGATAATTAAATGTTTGATAATTAATTATAGAAAAACCATGATAAACC
TGTTAAGTATTAACATTGTACGGTCTCG	TGTTTGAATCAGATTGCCTTTTACATAAATGGCACTA
TATTAAGCATTAACATTGTACGGTCTCA

>NZ_LT906446|7|7|2124693-2124926|CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTC	TCGCGTTTGATAATTAAATGTTTGATAATTAATTATAGAAAAACCATGATAAACCT
GTTAAGTATTAACATTGTACGGTC	TCGTGTTTGAATCAGATTGCCTTTTACATAAATGGCACTAT
ATTAAGCATTAACATTGTACGGTC	TCACATGAGTTAAGTCACTTGTTTTAGATGGACTTATTATA
GTTAAGTATTAATATTGTACAATG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027890016.1\|2118729_2119053_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377544
NZ_LT906446.1\|WP_027890670.1\|2127703_2127892_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|224089
NZ_LT906446.1\|WP_027890688.1\|2126623_2127040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890672.1\|2129149_2129674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_157738459.1\|2125198_2125393_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909594.1\|2125618_2125813_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131955
NZ_LT906446.1\|WP_155909571.1\|2122885_2123074_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|273593
NZ_LT906446.1\|WP_155909598.1\|2124341_2124530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_157738458.1\|2123922_2124117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890296.1\|2131714_2132224_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378186
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|225563
NZ_LT906446.1\|WP_027890687.1\|2125928_2126447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|379857

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	gnl\|CDD\|225563	COG3018, COG3018, Uncharacterized protein conserved in bacteria [Function unknown].	1.28161e-06
NZ_LT906446.1\|WP_027890013.1\|2114730_2115963_+\|ATP-binding-protein	gnl\|CDD\|377544	pfam05673, DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function.	6.58855e-124
NZ_LT906446.1\|WP_027890018.1\|2121013_2122123_+\|LPP20-family-lipoprotein	gnl\|CDD\|379857	pfam16548, FlgT_N, Flagellar assembly protein T, N-terminal domain. FlgT_N is the N-terminal domain of a family of flagellar proteins that make up part of the basal body of the flagellum. The flagellum is a large macromolecular assembly composed of three major parts: the basal body, the hook, and the filament. The basal body has two unique ring structures, the T ring and the H ring. FlgT is required to form and stabilize both ring structures. FlgT-N contributes to the construction of the H-ring structure, and adopts a two-layer alpha-beta sandwich architecture composed of a four-stranded anti-parallel beta-sheet and two alpha helices.	0.00453328
NZ_LT906446.1\|WP_027890014.1\|2116029_2117460_+\|PLP-dependent-aminotransferase-family-protein	gnl\|CDD\|224089	COG1167, ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism].	1.02258e-136
NZ_LT906446.1\|WP_027890012.1\|2113143_2114610_+\|HAMP-domain-containing-protein	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	6.25628e-56
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.52784e-12
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	gnl\|CDD\|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	4.85917e-35
NZ_LT906446.1\|WP_027890015.1\|2117471_2118449_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.62647e-53
NZ_LT906446.1\|WP_027890017.1\|2119203_2120925_+\|hypothetical-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	1.90064e-08

>NZ_LT906446.1|WP_155909598.1|2124341_2124530_+|hypothetical-protein
MKNKVNEIKTKICIPKGTLGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_157738458.1|2123922_2124117_+|hypothetical-protein
MKNKVNEIKTKICIPKGFFGGNCSNCIYWEEYNRNSDGRAYCSYYDDWYYPSERRGCFTYERNW
>NZ_LT906446.1|WP_155909571.1|2122885_2123074_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_027890018.1|2121013_2122123_+|LPP20-family-lipoprotein
MKKYVMIIVCLLCSLWWAVASAQSVNVSGHGMNYDEAERDALRNAIEQAVGTMVDSTALVKNGILLNDEIYKFSKGYITNYQVIDKRWLEDGLYEVNILADVDTNPNSKLMNELTRLGIINRQLRDPKIAVIIPEYHIRAKIPDPAGETAVINKLIEAGFSRIVYAEGMRDTIGKLDYLTNQDMQNIANNLNVDILVVGEAFSEGVGDVSKFIGNGRGRNTGILSCNARLEAKIFIAKTGQIISANGTYGKAADVTEFIAGKKALNNAGEKMGDYIVEKLLNYGSGNKQNIELKVITTDYNKVNMVNNALQNIRGVNSARVNSYDEGTATIDIKYSGTPQNIYNQLIQNINCNLKLQQITYNTLTIVVY
>NZ_LT906446.1|WP_027890017.1|2119203_2120925_+|hypothetical-protein
MVKNIVLFIMSLYRDDSIEKEYTDDSNLFKASCKHTNETALKYIAWKLNQEQQQIDEIYAFISEQVRETSLDKFKELIQDEYYKDKIIDVPLYNNGEMKGSFKSISEMFDKLQAYKEKNPDDTVVIHVDMTGGLRHASMLMLALIRMLKYIGMELGLVLYVNFNTAKIENASDIMDMFTLLGGAEEFNSFGSVNQIQNYFDKLNSKKLRTSSSALELLLEEMRDFSEAIKVCTNYKDMTNVLSLLNDSLKIYKRIIKSKSNRLSEQELFFAKLILVIEKTYADILPKDNKPSSVPAIIKWCAKRDFLQAAITFYTEWIPVYLIENKLVIIKDASIEEECRKNKAWSNWQVSFFKNYRMSQSSQIKLEDVEEYELTYSTVRGLIESDLSANKILGKVKDKNKKFSDFLKETIDFIKKTTRYRFYKAVVNLSNNSILKQILRESMPKNENDFEVYLTRRLIKENSNLEAVVLNSVKGIEKNRVREIFDLKEDKKLTTVEKSKERREMFKEMLEKNIIETKLPKERLLQFVEEYSNYVNDWRNQVSHANSLAASRESNFDIAQAIINSVNLIDEKF
>NZ_LT906446.1|WP_027890016.1|2118729_2119053_+|hypothetical-protein
MNKVSIKNNVYVVAKVSSKYKNKLDYYLIIPGRGYEYAFTKNYRKSCYIFCKSPILLNKVLYNRSHNIPLMVLKKYFHHNMSYLIDCLELDDFVLKRGAKNKYHKAA
>NZ_LT906446.1|WP_027890015.1|2117471_2118449_+|Gfo/Idh/MocA-family-oxidoreductase
MKIGIAGNGKIVREMIGAAKTVAGISIEAICSRAQSKAKAEKIAQECNISKVYTDYQKMLSDSDIDFIYVAVSNNVHYQYTKQALEAGKNVICEKPFTVKASETEELIQIAKDKHLFLFEAITVIYAPNYQYIKDNLKEIGTLHYVHANYAQYSSRYDKYLNKEVTPAFSPESAGGALYDLNIYNLHFIVGIFGMPKNIIYRANLGFNGIDTSGTALLDYDGFTVVCSAAKDSESVSGIVFQGEKGYMRLEGATNECALIRVNKKGETEKIVSKERYNHRMINEFIAFEQMFKQQDYKTCYENLDHSMMVMKVLEQARESGNLEF
>NZ_LT906446.1|WP_027890014.1|2116029_2117460_+|PLP-dependent-aminotransferase-family-protein
MNKNLIDFVSLNKQSKKPLYVQLYDEIAEKIKCKTLSAGYKLPPVRILAQQLNINNGTVVSAYRELEKNGYIFTRRGSGSYVAEQMNTISSEVDEKKDVLIDLAEEVNAENIPTDVINMSSVSLNPEMISMEIFQKAIDEILKRDKGYAFTYQDSKGYLPLRQSIVQSLAQKKINTTQQNVQIISGAQQGIDIVARALLKHGDIVFVESPTYPGAMAAFRSCGAKIIDIKLTKEGIDLADLENKLKLFKPRLIYVMPNVQNPTGISYSKYVRHRLMGLARYHDVYILEDDYIGGLYYSKNEMLPLKTYDTDDRVIYIRTLSKVFMPGLRLAYLIVPSDLAQRLLNVKYISDIATSGLTQRIFDYYLREGLWQKHLNSIRSIYKTKFDFILKMMKKYLPKDISYIKPTGGLSVWLNLPERLLADDVIENAKKQGVIISNGAPFFVRRAPHRQLRISFAVLSLAEIKTGIKILAEIMK
>NZ_LT906446.1|WP_027890013.1|2114730_2115963_+|ATP-binding-protein
MLDLHNLLVCHHLLDDKTIEDFNKLMGGASVNKGKLAAQFIEQAEKLGLSGNIIKVYILYMLAHKNNCVSYAVESSGGKIGTSLYKAFCHDIDILSKLLVLKPSIVLGCEYLDDYEPTVKNVSAAFKTLEENLLTAKTVEEKADAFIEYYRTYGSGDMADYRAFRWSNSDEELVGIKYFEAMSLDELIGYEQQKQQLNDNTLAFVEGKPANNVLLVGARGTGKSSGVKAVVNSFFDKGLRLVQLTKDQLIALPIIMERLRTYSSKKFIIFLDDLSFEEFEVEYKYLKSAIEGGASAKPENVLIYATSNRRHLIKESYKNRGVDDDDMHRNDTLNETISLSDRFGLIINYLSPNQQEYLDIVDGLLRQHGVVLDKEELRIKAGAWAQEHSGRSGRIAQQFVTYYLGQIYNK
>NZ_LT906446.1|WP_027890012.1|2113143_2114610_+|HAMP-domain-containing-protein
MLSKLKQYIKEHIHLRLRYMPISLKLAFIYSIMLSMILIITLSATLVGIHYVLYHEAEISITLSANFVEKKANEKGLEEIIKDVEKSSLIPGVVMRITDKDNNVIYDSMPMYISNDKVQNNLQLQTQSPSFGDYIRNALLPENLKFINFRHFWIFYTQRTIEKDDNVYTLHFLRTITAEKVFLEELSETILYVGLVGVLISIICGFLLSRKLLKPLSDITKKVKDIEIQDLNKRIEVPPTHDEIEELANTFNLMLERLQKGFEQQRQFVSDASHELRTPATVICGYSDMLARWGKDDPQTADECITAIHSEAINMQRLIEKLLFLARADQKRQVLHKESISMKPLIADIAKDTQLIAPQHSVTCSLNEDGYIFADPLCMRQMLRIFLDNSIKYTPDGGKIEISSHNDGNKMIVKISDNGIGIGKEEQKKIFERFYRVDAARTKNGVGGTGLGLSIAEWIAQAHDIEIKLDSELEKGTTITLFIPLDFG
>NZ_LT906446.1|WP_157738459.1|2125198_2125393_+|hypothetical-protein
MKNKANEIKIKICIPKGFFGGNCSDCIHWEEYNRNSDGRAYCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_155909594.1|2125618_2125813_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSDCIHWEEYNRASDGRAHCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_027890687.1|2125928_2126447_+|hypothetical-protein
MEKTIITFVLLAMVTLVPAVGFASENSSKEIKHLNGVSWGESYHEFSEKYSIRPILEACEINLDKKINLYGQEMDTKAIAYFNNDRLFMMQYCFPEKLTDEEFDKVTKVITKELGEVVAEDKNKEIGKMIAWRNDDELVALNKEGIYYLGLSLFDTDNIFSLERMNVLSVKR
>NZ_LT906446.1|WP_027890688.1|2126623_2127040_+|hypothetical-protein
MRIKENIFKEIVESPAPPPEVGGIIGGKEDIITCYFADKGSKENCYDSYYPSTDLLNKQIDKWQDDGIDFYGIYHTHFAGDDGLSSSDRRYIVNIMQAMPSQIQYLYFPIVFKNNMLIYKAIRENNIVKIVQEDIEII
>NZ_LT906446.1|WP_027890670.1|2127703_2127892_+|hypothetical-protein
MKTWMKNFILSILAIIAVIIFHEQIWHGILYVLSFFLGLIIDFVSILVVIGVGMYIILDLLT
>NZ_LT906446.1|WP_027890671.1|2128052_2128934_+|hypothetical-protein
MKKYFAHFISLAVFVMILGTSLVSEAAMKTVAVGNFIDGTQSRYGKMICEQLQSSIQNGLVQNKNYTVVERSNLDQIFRELGLQNSGVVNSSSAIEIGNLSGADYTLMGKVVEAEINPYNNLAYEGLKAKVAVSVQIVDNETGQVLSSDMVSDTDSSATKNNLKKFIKSDLVPGHMSVNSDSLIYNAAEKVANKVLERMNKINPLVGMVVAVKPNEDTVTFDLGYEDGVKEGDIYTIYAEAEPIVHPVTGEILGVDEKYVGTVKVEEVRNNLSIAKIKDCEVTPMVKDKVKRK
>NZ_LT906446.1|WP_027890672.1|2129149_2129674_+|hypothetical-protein
MKKIIITFVLLAMVALVPAVSFASENSNNSGIKQLKDIAWGESYHDFSTKYSIKPLLETCEITLDEKVNLYGQEMDTRAVACFYNDRLFMIQYCFPEKLTDEEFDKLTEVMTKELGEVGAKNENSIIGEMKGWKNNDELIALNKEGIYYIDFNFLDTDELCSLEKIKSLNINNK
>NZ_LT906446.1|WP_036254934.1|2129784_2130669_+|LPP20-family-lipoprotein
MKKTLIVLTSAALFSFGASILPVNTYFAPVKAEAQYQNPAYAQTETITADGYGVLPPNKPFGQAKLMARRAAVVEAQRNLLETVKDVAIDSETNVEMSMTLNDTIHSKVSGVIRGARVVDEEYIREDGIYRVTMSVPMYGDGSLGQVVFDNVIGNNQKVPVPAPSPTYNPNTSQINGNYTGLVIRARGAGLVRTFCPAIYDTSGRAIYGVYNVDKKYAIDYGVVGYAKGQQGWDTVRMGTSRAGSNPLVVDIVEVRQRVANKCDVVISVEDADRILAENRHSHFLDNYAVMFEI
>NZ_LT906446.1|WP_027890296.1|2131714_2132224_+|hypothetical-protein
MKKLLMALALAIAVCLQSGVSMAATEDMAKIDSIEVKELGLNLIKVEMPLEKGFESIYGQDYAPLTIIVYNDKSDMIAIDEPFAHKLTSEKYDYVKEQMIKKLGEPDKVENLADNTITIWYTDDKKNIDVVLNSKSITQFFRQDDADVLKKYKLSTQIKDFISCIVSQY
>NZ_LT906446.1|WP_051177623.1|2132256_2132760_+|hypothetical-protein
MKKIFLLIVSLCIFSSVCMASPVYYYNYSNTSNYAYEPNTDKNYAQSVAALVNRERLKAGVRPLILNPYLCNRSDIRANELAIIFAHTRPDGSQFYTVLDRRKFHYMTAGENAAAGASSPQEVVNIWMNSPGHRQNILNPKFRYIGVGYAYVPNSQYNNYWIQIFSD

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Crispr_ID: NZ_LT906446_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_8

2131090-2131507

TypeIII

Consensus_repeat	Method
GTTAAGCATTAACATTGTACGGTCTCGTC	PILER-CR
GTTAAGCATTAACATTGTACGGTCTCGTC	CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTCTCGTC	CRT

6 spacers

cas10

The CRISPR arrays of NZ_LT906446_8

>merge|NZ_LT906446|8|2131090-2131507|PILER-CR,CRISPRCasFinder,CRT
GTTAAGCATTAACATTGTACGGTCTCGTCGCATGAAAGCCCATTTTATGATGAAGATGCTTTTGCGTTAAGCATTAACATTGTACGGTCTCGTCTAAAGTTTTTTCTATTGTTTCAAATTTAACCTCACGTTAAGCATTAACATTGTACGGTCTCGTCTCAACATAAATCGGGATAAGATAGCCAGTGTCGAAGTTAAGCATTAACATTGTACGGTCTCGTCTCAAAAGAACCAAGTTTTCTTACTTGATTGAGTTGGTTAAGCATTAACATTGTACGGTCTCGTCACCAGCTAAAGAATATTCTTCTTCACTCCAGCGAACCGTTAAGCATTAACATTGTACGGTCTCGTCATTGGTCGCAATCTGCTTATCCATGGGCAGTTGATTTGTTAAGCATTAACAATGTATAATGTAATT

>NZ_LT906446|8|7|2131090-2131441|PILER-CR
GTTAAGCATTAACATTGTACGGTCTCGTC	GCATGAAAGCCCATTTTATGATGAAGATGCTTTTGC
GTTAAGCATTAACATTGTACGGTCTCGTC	TAAAGTTTTTTCTATTGTTTCAAATTTAACCTCAC
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAACATAAATCGGGATAAGATAGCCAGTGTCGAA
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAAAAGAACCAAGTTTTCTTACTTGATTGAGTTG
GTTAAGCATTAACATTGTACGGTCTCGTC	ACCAGCTAAAGAATATTCTTCTTCACTCCAGCGAACC
GTTAAGCATTAACATTGTACGGTCTCGTC

>NZ_LT906446|8|8|2131090-2131507|CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTCTCGTC	GCATGAAAGCCCATTTTATGATGAAGATGCTTTTGC
GTTAAGCATTAACATTGTACGGTCTCGTC	TAAAGTTTTTTCTATTGTTTCAAATTTAACCTCAC
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAACATAAATCGGGATAAGATAGCCAGTGTCGAA
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAAAAGAACCAAGTTTTCTTACTTGATTGAGTTG
GTTAAGCATTAACATTGTACGGTCTCGTC	ACCAGCTAAAGAATATTCTTCTTCACTCCAGCGAACC
GTTAAGCATTAACATTGTACGGTCTCGTC	ATTGGTCGCAATCTGCTTATCCATGGGCAGTTGATTT
GTTAAGCATTAACAATGTATAATGTAATT

>NZ_LT906446|8|7|2131090-2131507|CRT
GTTAAGCATTAACATTGTACGGTCTCGTC	GCATGAAAGCCCATTTTATGATGAAGATGCTTTTGC
GTTAAGCATTAACATTGTACGGTCTCGTC	TAAAGTTTTTTCTATTGTTTCAAATTTAACCTCAC
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAACATAAATCGGGATAAGATAGCCAGTGTCGAA
GTTAAGCATTAACATTGTACGGTCTCGTC	TCAAAAGAACCAAGTTTTCTTACTTGATTGAGTTG
GTTAAGCATTAACATTGTACGGTCTCGTC	ACCAGCTAAAGAATATTCTTCTTCACTCCAGCGAACC
GTTAAGCATTAACATTGTACGGTCTCGTC	ATTGGTCGCAATCTGCTTATCCATGGGCAGTTGATTT
GTTAAGCATTAACAATGTATAATGTAATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_027890301.1\|2137731_2137950_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909594.1\|2125618_2125813_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890670.1\|2127703_2127892_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890688.1\|2126623_2127040_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890296.1\|2131714_2132224_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_157738459.1\|2125198_2125393_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890303.1\|2138780_2140709_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890298.1\|2133966_2135064_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890299.1\|2135209_2135863_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131955
NZ_LT906446.1\|WP_027890300.1\|2135886_2137122_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|225563
NZ_LT906446.1\|WP_027890297.1\|2132879_2133437_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_155909598.1\|2124341_2124530_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890304.1\|2140797_2142447_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274209
NZ_LT906446.1\|WP_157738458.1\|2123922_2124117_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890302.1\|2138082_2138742_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187863
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655
NZ_LT906446.1\|WP_027890687.1\|2125928_2126447_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890672.1\|2129149_2129674_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_027890302.1\|2138082_2138742_+\|hypothetical-protein	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	0.000619615
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	gnl\|CDD\|225563	COG3018, COG3018, Uncharacterized protein conserved in bacteria [Function unknown].	1.28161e-06
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	gnl\|CDD\|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	4.85917e-35
NZ_LT906446.1\|WP_027890304.1\|2140797_2142447_+\|hypothetical-protein	gnl\|CDD\|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	1.29892e-05
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.52784e-12

>NZ_LT906446.1|WP_036254934.1|2129784_2130669_+|LPP20-family-lipoprotein
MKKTLIVLTSAALFSFGASILPVNTYFAPVKAEAQYQNPAYAQTETITADGYGVLPPNKPFGQAKLMARRAAVVEAQRNLLETVKDVAIDSETNVEMSMTLNDTIHSKVSGVIRGARVVDEEYIREDGIYRVTMSVPMYGDGSLGQVVFDNVIGNNQKVPVPAPSPTYNPNTSQINGNYTGLVIRARGAGLVRTFCPAIYDTSGRAIYGVYNVDKKYAIDYGVVGYAKGQQGWDTVRMGTSRAGSNPLVVDIVEVRQRVANKCDVVISVEDADRILAENRHSHFLDNYAVMFEI
>NZ_LT906446.1|WP_027890672.1|2129149_2129674_+|hypothetical-protein
MKKIIITFVLLAMVALVPAVSFASENSNNSGIKQLKDIAWGESYHDFSTKYSIKPLLETCEITLDEKVNLYGQEMDTRAVACFYNDRLFMIQYCFPEKLTDEEFDKLTEVMTKELGEVGAKNENSIIGEMKGWKNNDELIALNKEGIYYIDFNFLDTDELCSLEKIKSLNINNK
>NZ_LT906446.1|WP_027890671.1|2128052_2128934_+|hypothetical-protein
MKKYFAHFISLAVFVMILGTSLVSEAAMKTVAVGNFIDGTQSRYGKMICEQLQSSIQNGLVQNKNYTVVERSNLDQIFRELGLQNSGVVNSSSAIEIGNLSGADYTLMGKVVEAEINPYNNLAYEGLKAKVAVSVQIVDNETGQVLSSDMVSDTDSSATKNNLKKFIKSDLVPGHMSVNSDSLIYNAAEKVANKVLERMNKINPLVGMVVAVKPNEDTVTFDLGYEDGVKEGDIYTIYAEAEPIVHPVTGEILGVDEKYVGTVKVEEVRNNLSIAKIKDCEVTPMVKDKVKRK
>NZ_LT906446.1|WP_027890670.1|2127703_2127892_+|hypothetical-protein
MKTWMKNFILSILAIIAVIIFHEQIWHGILYVLSFFLGLIIDFVSILVVIGVGMYIILDLLT
>NZ_LT906446.1|WP_027890688.1|2126623_2127040_+|hypothetical-protein
MRIKENIFKEIVESPAPPPEVGGIIGGKEDIITCYFADKGSKENCYDSYYPSTDLLNKQIDKWQDDGIDFYGIYHTHFAGDDGLSSSDRRYIVNIMQAMPSQIQYLYFPIVFKNNMLIYKAIRENNIVKIVQEDIEII
>NZ_LT906446.1|WP_027890687.1|2125928_2126447_+|hypothetical-protein
MEKTIITFVLLAMVTLVPAVGFASENSSKEIKHLNGVSWGESYHEFSEKYSIRPILEACEINLDKKINLYGQEMDTKAIAYFNNDRLFMMQYCFPEKLTDEEFDKVTKVITKELGEVVAEDKNKEIGKMIAWRNDDELVALNKEGIYYLGLSLFDTDNIFSLERMNVLSVKR
>NZ_LT906446.1|WP_155909594.1|2125618_2125813_+|hypothetical-protein
MKNKANEIKTKICIPKGFFGGNCSDCIHWEEYNRASDGRAHCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_157738459.1|2125198_2125393_+|hypothetical-protein
MKNKANEIKIKICIPKGFFGGNCSDCIHWEEYNRNSDGRAYCSYYDNWYYPSERRGCFAYERNW
>NZ_LT906446.1|WP_155909598.1|2124341_2124530_+|hypothetical-protein
MKNKVNEIKTKICIPKGTLGGNCSGCRYWEEYNRDSSGRAFCSYYDDWYYPSERRGCFARKE
>NZ_LT906446.1|WP_157738458.1|2123922_2124117_+|hypothetical-protein
MKNKVNEIKTKICIPKGFFGGNCSNCIYWEEYNRNSDGRAYCSYYDDWYYPSERRGCFTYERNW
>NZ_LT906446.1|WP_027890296.1|2131714_2132224_+|hypothetical-protein
MKKLLMALALAIAVCLQSGVSMAATEDMAKIDSIEVKELGLNLIKVEMPLEKGFESIYGQDYAPLTIIVYNDKSDMIAIDEPFAHKLTSEKYDYVKEQMIKKLGEPDKVENLADNTITIWYTDDKKNIDVVLNSKSITQFFRQDDADVLKKYKLSTQIKDFISCIVSQY
>NZ_LT906446.1|WP_051177623.1|2132256_2132760_+|hypothetical-protein
MKKIFLLIVSLCIFSSVCMASPVYYYNYSNTSNYAYEPNTDKNYAQSVAALVNRERLKAGVRPLILNPYLCNRSDIRANELAIIFAHTRPDGSQFYTVLDRRKFHYMTAGENAAAGASSPQEVVNIWMNSPGHRQNILNPKFRYIGVGYAYVPNSQYNNYWIQIFSD
>NZ_LT906446.1|WP_027890297.1|2132879_2133437_+|hypothetical-protein
MKKEMTPVITSMIKRIKSAGYEFNIYNQIESFCIESMINSMKLGIAKEKSLKKSFSGQELMPFAFRFYNCDSEMIVIQLPFKHKLIDEQFESIEKNIGKPDKIKKNKEDTMAIWYFVVDEKERAYMLNSSAFIIVEVDSVIKILDSFNLPMEIEDFVNVVISLDKETPEDYEDERIAQNFEYILC
>NZ_LT906446.1|WP_027890298.1|2133966_2135064_+|hypothetical-protein
MTKETTTKIAALFDFIEYCDYKNYPCNDFKLYYMRNFFKDEFEIYLMKKKISSQTVFGYPILPYVFSVECCSCGGSMAEKYIFTEELTPEQFENLKEELSQKYGKYDEIKNFTNGVTIVWRVESDLYALNSKVFTKILYKYNMECIFEALKYFRKYDLVIDIIDLIKLIINLDKEKYETTYDYGYIYDCAPYGEDELTEEEKRQFIEDLEAYRRGEYEAELEFIELRDKTKKLFEHKDIYIREIETSEKFSSLYGQKISEYTHTVKTYINGLIAINMPFIKELTSEQYENVKKEMLKEHGEPDEIIDFKEGTVIIWYSQDMKDISYALNPKSIIIFIEDYVLYALDRYHISISNAEFVNFVANKS
>NZ_LT906446.1|WP_027890299.1|2135209_2135863_+|hypothetical-protein
MAKRPVYIVSNTKPYFKCKMTDFEYFSGFSVKQKQKNIRSLHDAFNVLNPSSRILEISTKSEDSLGIALSAFNLMVKNEKGEDLFSVEAAFQSSKVFEKGGPYTDLLYVSSKEAKKDKRLKTSGSIIGFNFQGEEFKSRPKTFFYNWLYINALNSNEELAEAIMNFDAFTDIEFNPQKSLNCQAEAVALFVSLKKNNLLQKVLKNKDDFMQTVYFFD
>NZ_LT906446.1|WP_027890300.1|2135886_2137122_+|hypothetical-protein
MYINLENVDKIKKANIELKGITIILTSKYAPKNLIGNVIFSSDVLLGRYVNKLYEHRAFEIVEMCAQNTSIESLSNINKLYLFNKIDRELKKKARLYNTLEEEIREILDIFETVLKQKSSIAKQIDIETYLGKINQLLHNKLQQSFIEIVKTKIKTEFLPKVSFEASDIKIEIIEDNEVKKFTQKNYQCTELKVLNKSNAVMNMESLGICDILADGYRKDFNYSEKKLYKRVLEVCFVSNGNSVSLINDVSDRDNLEVYGIDKNVINNFYDILDKVVDSIKKTSDNKYYLVYKYLNKKINLTDAPRDLRCFVDFKILLERYFFCGHKWAKPKIIVFKEPESYLNDTWQDLYAEFVVLLQKYIIPNLIIRTENKDLMAKIKHYIKIHDSIAKVNVYEAVKNNDGFNLNKLID
>NZ_LT906446.1|WP_027890301.1|2137731_2137950_+|hypothetical-protein
MKALFEFVWFLIKVCLMIFAGVVFGGIAHFIIESELIFVILGLILLYFFGPYILEIVLMYSFAKEIKKELDK
>NZ_LT906446.1|WP_027890302.1|2138082_2138742_+|hypothetical-protein
MRKVFLSSMLLNELKPEDPTYYTSDDFELSENRYDFPMTYLIDDKVKANDEIVIITAIQQDSGNNVNNATVNYKKYKAEVEKILQERNVNFKFEEIMLTENFDSLTFNKFFKQVAVLINDNDQLFVDVTFGMKPYCISLFVAVAYAEKAARNVDVDTVIYAQKYSGFSRAKTAEEKAKDPSKSRIYDITGLFYLNAIAGNAKPGQKHKLDKALDLLIND
>NZ_LT906446.1|WP_027890303.1|2138780_2140709_+|hypothetical-protein
MGNTNDSKEKVKARYKKSKEYIEINRDIEEEKDKKEDKKDINKLKNEIEGYVKTYLQYLFEGNLKRKEENNINLKITRKLMLLDYKYDAFAKVRKKALNLLPNQDKNIYLSNVDIVQFKKVTKDSLDNIVIEYKKDTTLLSFFTIFEKEYYLGLKLLAETKIKEVREIRNQIEDSVREYVQGTADEILSDTRKTYLVMKIVKNLIFLEKEYDFFAKQRLGALKILNYYNKKLTFYEAKSDGYVSLVKKILDSKVKEYKDTGEIYSFIIEFRKKYYNEMREAVVNLLNEENVQYKMRKSFVKKEIRILYKELFKNDKAFLRKVTKQLNDKKSFNYHTIKYFFVKNILLYIELPSENEEVNNNVYDYIRKEEIQKGTPKQEIEYLIKTRSKEDLEQLKKNVSDILNRFYSVDRGGDNNKYIYKAMKNKNALEEQLKNMKGIDINKLKDIELQMEAIETCLYKIQKVFEESLIVDIFEMNEDGKEYSILEHRALKQPSFEYAKEKFFSYIDIYENIKDKLSESSRTFFKYVFGYIILEFKRRGHDDVELFDYIKDETNFIEFYNKNIPDTENPNYIENATDKKYDLPNEKIVHKAIAFITDYLDIAYDTGRKHKNVVLKEMYKTIKSENTGLRYFRRFLEEDFLQ
>NZ_LT906446.1|WP_027890304.1|2140797_2142447_+|hypothetical-protein
MLNSVGAILLDTRSIQKYVFSCNRLKTNIGASFLVDSIFSDLMVNKILPSLNLKMPEFSWNEVDNVQMLEDDSIECEVAYIGGGNMIILVRKQDEDVIELCKKIVGSWSKEILIKAPGLKTGAAIGMLDIDSEHFQKSLGILYKQLKDNQNTILPQVDVPYVGFTLECDYSGKTAEYLRGRVEDSIINEFDNKMVSAEIVAKSSAYNVATEKLKEEYKDILGNRFDFVTKFDNLGYKDNESYISVVHIDGNNMGIKFASCKNMQERKKLSLRTAQIVKRGFYKLLKSVVIDFKEGIYDKSLNINKMKNRYLPIRPIIIGGDDITFVCPGRLGLEYAKRFIQFVSKEQLLDEKLYSNAQSYAGKIFNNQNIKVNNNMSCCAGVAIVPAKYPFYRAYELAEQLCGSAKKKSREDDESFVDFAILHGDMSPTLDQLCVQQYEAPEGYLHYGPYCITQEQNDKSNINDLFSLIEKIKKVPNNKIKDLRNVLNEDNHSIVRFLENCPEVENILKDELQKEDVGASDLWQYMKNEKILKTRYVDAIELIDFSLKV

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Crispr_ID: NZ_LT906446_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT906446_9

2137268-2137494

TypeIII

Consensus_repeat	Method
GGTTAAGCATTAACATTGTACGGTCTCT	CRT
GTTAAGCATTAACATTGTACGGTCTCT	CRISPRCasFinder

3 spacers

cas10,csm3gr7,csx10gr5,csx19

The CRISPR arrays of NZ_LT906446_9

>merge|NZ_LT906446|9|2137268-2137494|CRT,CRISPRCasFinder
GGTTAAGCATTAACATTGTACGGTCTCTTGTTTCAAATACAAATAATCCTAATTTTACATTACAATTGTTAAGCATTAACATTGTACGGTCTCTTGTTAATACAAGACTTAACATTTAAAAGCGTCGGTAACGGGTTAAGCATTAACATTGTACGGTCTCTCATTACGTAGAATGAATTACGTTTTTTTCTCGCTTTTCGGTTAAGCCTTAATATTGTACGGTCTCT

>NZ_LT906446|9|8|2137268-2137494|CRT
GGTTAAGCATTAACATTGTACGGTCTCT	TGTTTCAAATACAAATAATCCTAATTTTACATTACAAT
TGTTAAGCATTAACATTGTACGGTCTCT	TGTTAATACAAGACTTAACATTTAAAAGCGTCGGTAACG
GGTTAAGCATTAACATTGTACGGTCTCT	CATTACGTAGAATGAATTACGTTTTTTTCTCGCTTTTC
GGTTAAGCCTTAATATTGTACGGTCTCT

>NZ_LT906446|9|9|2137269-2137494|CRISPRCasFinder
GTTAAGCATTAACATTGTACGGTCTCT	TGTTTCAAATACAAATAATCCTAATTTTACATTACAATT
GTTAAGCATTAACATTGTACGGTCTCT	TGTTAATACAAGACTTAACATTTAAAAGCGTCGGTAACGG
GTTAAGCATTAACATTGTACGGTCTCT	CATTACGTAGAATGAATTACGTTTTTTTCTCGCTTTTCG
GTTAAGCCTTAATATTGTACGGTCTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT906446.1\|WP_155909578.1\|2146099_2146702_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NZ_LT906446.1\|WP_027890301.1\|2137731_2137950_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890307.1\|2146796_2148581_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NZ_LT906446.1\|WP_027890308.1\|2148669_2149242_-\|cytidylate-kinase-like-family-protein	unknown	unknown	gnl\|CDD\|379060
NZ_LT906446.1\|WP_027890670.1\|2127703_2127892_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890296.1\|2131714_2132224_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890306.1\|2144706_2146137_+\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NZ_LT906446.1\|WP_027890303.1\|2138780_2140709_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890298.1\|2133966_2135064_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890299.1\|2135209_2135863_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890300.1\|2135886_2137122_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131955
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	unknown	unknown	gnl\|CDD\|225563
NZ_LT906446.1\|WP_027890305.1\|2143125_2144679_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NZ_LT906446.1\|WP_027890297.1\|2132879_2133437_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_051177624.1\|2142466_2143108_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NZ_LT906446.1\|WP_027890304.1\|2140797_2142447_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274209
NZ_LT906446.1\|WP_027890302.1\|2138082_2138742_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|187863
NZ_LT906446.1\|WP_027890672.1\|2129149_2129674_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367655

Protein	Function_ID	Function_description	E-value
NZ_LT906446.1\|WP_036254934.1\|2129784_2130669_+\|LPP20-family-lipoprotein	gnl\|CDD\|225563	COG3018, COG3018, Uncharacterized protein conserved in bacteria [Function unknown].	1.28161e-06
NZ_LT906446.1\|WP_027890305.1\|2143125_2144679_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	1.22183e-20
NZ_LT906446.1\|WP_051177624.1\|2142466_2143108_+\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.73459e-12
NZ_LT906446.1\|WP_027890308.1\|2148669_2149242_-\|cytidylate-kinase-like-family-protein	gnl\|CDD\|379060	pfam13189, Cytidylate_kin2, Cytidylate kinase-like family. This family includes enzymes related to cytidylate kinase.	8.53884e-50
NZ_LT906446.1\|WP_027890304.1\|2140797_2142447_+\|hypothetical-protein	gnl\|CDD\|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	1.29892e-05
NZ_LT906446.1\|WP_155909578.1\|2146099_2146702_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	9.02284e-21
NZ_LT906446.1\|WP_027890302.1\|2138082_2138742_+\|hypothetical-protein	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	0.000619615
NZ_LT906446.1\|WP_027890306.1\|2144706_2146137_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.2509e-13
NZ_LT906446.1\|WP_027890307.1\|2146796_2148581_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.74826e-56
NZ_LT906446.1\|WP_051177623.1\|2132256_2132760_+\|hypothetical-protein	gnl\|CDD\|131955	TIGR02909, conserved_hypothetical_protein, uncharacterized protein, YkwD family. Members of this protein family represent a subset of those belonging to pfam00188 (SCP-like extracellular protein). Based on currently cuttoffs for this model, all member proteins are found in Bacteria capable of endospore formation. Members include a named but uncharacterized protein, YkwD of Bacillus subtilis. Only the C-terminal region is well-conserved and is included in the seed alignment for this model. Three members of this family have an N-terminal domain homologous to the spore coat assembly protein SafA.	4.85917e-35
NZ_LT906446.1\|WP_027890671.1\|2128052_2128934_+\|hypothetical-protein	gnl\|CDD\|367655	pfam03783, CsgG, Curli production assembly/transport component CsgG. CsgG is an outer membrane-located lipoprotein that is highly resistant to protease digestion. During curli assembly, an adhesive surface fibre, CsgG is required to maintain the stability of CsgA and CsgB.	1.52784e-12

>NZ_LT906446.1|WP_027890300.1|2135886_2137122_+|hypothetical-protein
MYINLENVDKIKKANIELKGITIILTSKYAPKNLIGNVIFSSDVLLGRYVNKLYEHRAFEIVEMCAQNTSIESLSNINKLYLFNKIDRELKKKARLYNTLEEEIREILDIFETVLKQKSSIAKQIDIETYLGKINQLLHNKLQQSFIEIVKTKIKTEFLPKVSFEASDIKIEIIEDNEVKKFTQKNYQCTELKVLNKSNAVMNMESLGICDILADGYRKDFNYSEKKLYKRVLEVCFVSNGNSVSLINDVSDRDNLEVYGIDKNVINNFYDILDKVVDSIKKTSDNKYYLVYKYLNKKINLTDAPRDLRCFVDFKILLERYFFCGHKWAKPKIIVFKEPESYLNDTWQDLYAEFVVLLQKYIIPNLIIRTENKDLMAKIKHYIKIHDSIAKVNVYEAVKNNDGFNLNKLID
>NZ_LT906446.1|WP_027890299.1|2135209_2135863_+|hypothetical-protein
MAKRPVYIVSNTKPYFKCKMTDFEYFSGFSVKQKQKNIRSLHDAFNVLNPSSRILEISTKSEDSLGIALSAFNLMVKNEKGEDLFSVEAAFQSSKVFEKGGPYTDLLYVSSKEAKKDKRLKTSGSIIGFNFQGEEFKSRPKTFFYNWLYINALNSNEELAEAIMNFDAFTDIEFNPQKSLNCQAEAVALFVSLKKNNLLQKVLKNKDDFMQTVYFFD
>NZ_LT906446.1|WP_027890298.1|2133966_2135064_+|hypothetical-protein
MTKETTTKIAALFDFIEYCDYKNYPCNDFKLYYMRNFFKDEFEIYLMKKKISSQTVFGYPILPYVFSVECCSCGGSMAEKYIFTEELTPEQFENLKEELSQKYGKYDEIKNFTNGVTIVWRVESDLYALNSKVFTKILYKYNMECIFEALKYFRKYDLVIDIIDLIKLIINLDKEKYETTYDYGYIYDCAPYGEDELTEEEKRQFIEDLEAYRRGEYEAELEFIELRDKTKKLFEHKDIYIREIETSEKFSSLYGQKISEYTHTVKTYINGLIAINMPFIKELTSEQYENVKKEMLKEHGEPDEIIDFKEGTVIIWYSQDMKDISYALNPKSIIIFIEDYVLYALDRYHISISNAEFVNFVANKS
>NZ_LT906446.1|WP_027890297.1|2132879_2133437_+|hypothetical-protein
MKKEMTPVITSMIKRIKSAGYEFNIYNQIESFCIESMINSMKLGIAKEKSLKKSFSGQELMPFAFRFYNCDSEMIVIQLPFKHKLIDEQFESIEKNIGKPDKIKKNKEDTMAIWYFVVDEKERAYMLNSSAFIIVEVDSVIKILDSFNLPMEIEDFVNVVISLDKETPEDYEDERIAQNFEYILC
>NZ_LT906446.1|WP_051177623.1|2132256_2132760_+|hypothetical-protein
MKKIFLLIVSLCIFSSVCMASPVYYYNYSNTSNYAYEPNTDKNYAQSVAALVNRERLKAGVRPLILNPYLCNRSDIRANELAIIFAHTRPDGSQFYTVLDRRKFHYMTAGENAAAGASSPQEVVNIWMNSPGHRQNILNPKFRYIGVGYAYVPNSQYNNYWIQIFSD
>NZ_LT906446.1|WP_027890296.1|2131714_2132224_+|hypothetical-protein
MKKLLMALALAIAVCLQSGVSMAATEDMAKIDSIEVKELGLNLIKVEMPLEKGFESIYGQDYAPLTIIVYNDKSDMIAIDEPFAHKLTSEKYDYVKEQMIKKLGEPDKVENLADNTITIWYTDDKKNIDVVLNSKSITQFFRQDDADVLKKYKLSTQIKDFISCIVSQY
>NZ_LT906446.1|WP_036254934.1|2129784_2130669_+|LPP20-family-lipoprotein
MKKTLIVLTSAALFSFGASILPVNTYFAPVKAEAQYQNPAYAQTETITADGYGVLPPNKPFGQAKLMARRAAVVEAQRNLLETVKDVAIDSETNVEMSMTLNDTIHSKVSGVIRGARVVDEEYIREDGIYRVTMSVPMYGDGSLGQVVFDNVIGNNQKVPVPAPSPTYNPNTSQINGNYTGLVIRARGAGLVRTFCPAIYDTSGRAIYGVYNVDKKYAIDYGVVGYAKGQQGWDTVRMGTSRAGSNPLVVDIVEVRQRVANKCDVVISVEDADRILAENRHSHFLDNYAVMFEI
>NZ_LT906446.1|WP_027890672.1|2129149_2129674_+|hypothetical-protein
MKKIIITFVLLAMVALVPAVSFASENSNNSGIKQLKDIAWGESYHDFSTKYSIKPLLETCEITLDEKVNLYGQEMDTRAVACFYNDRLFMIQYCFPEKLTDEEFDKLTEVMTKELGEVGAKNENSIIGEMKGWKNNDELIALNKEGIYYIDFNFLDTDELCSLEKIKSLNINNK
>NZ_LT906446.1|WP_027890671.1|2128052_2128934_+|hypothetical-protein
MKKYFAHFISLAVFVMILGTSLVSEAAMKTVAVGNFIDGTQSRYGKMICEQLQSSIQNGLVQNKNYTVVERSNLDQIFRELGLQNSGVVNSSSAIEIGNLSGADYTLMGKVVEAEINPYNNLAYEGLKAKVAVSVQIVDNETGQVLSSDMVSDTDSSATKNNLKKFIKSDLVPGHMSVNSDSLIYNAAEKVANKVLERMNKINPLVGMVVAVKPNEDTVTFDLGYEDGVKEGDIYTIYAEAEPIVHPVTGEILGVDEKYVGTVKVEEVRNNLSIAKIKDCEVTPMVKDKVKRK
>NZ_LT906446.1|WP_027890670.1|2127703_2127892_+|hypothetical-protein
MKTWMKNFILSILAIIAVIIFHEQIWHGILYVLSFFLGLIIDFVSILVVIGVGMYIILDLLT
>NZ_LT906446.1|WP_027890301.1|2137731_2137950_+|hypothetical-protein
MKALFEFVWFLIKVCLMIFAGVVFGGIAHFIIESELIFVILGLILLYFFGPYILEIVLMYSFAKEIKKELDK
>NZ_LT906446.1|WP_027890302.1|2138082_2138742_+|hypothetical-protein
MRKVFLSSMLLNELKPEDPTYYTSDDFELSENRYDFPMTYLIDDKVKANDEIVIITAIQQDSGNNVNNATVNYKKYKAEVEKILQERNVNFKFEEIMLTENFDSLTFNKFFKQVAVLINDNDQLFVDVTFGMKPYCISLFVAVAYAEKAARNVDVDTVIYAQKYSGFSRAKTAEEKAKDPSKSRIYDITGLFYLNAIAGNAKPGQKHKLDKALDLLIND
>NZ_LT906446.1|WP_027890303.1|2138780_2140709_+|hypothetical-protein
MGNTNDSKEKVKARYKKSKEYIEINRDIEEEKDKKEDKKDINKLKNEIEGYVKTYLQYLFEGNLKRKEENNINLKITRKLMLLDYKYDAFAKVRKKALNLLPNQDKNIYLSNVDIVQFKKVTKDSLDNIVIEYKKDTTLLSFFTIFEKEYYLGLKLLAETKIKEVREIRNQIEDSVREYVQGTADEILSDTRKTYLVMKIVKNLIFLEKEYDFFAKQRLGALKILNYYNKKLTFYEAKSDGYVSLVKKILDSKVKEYKDTGEIYSFIIEFRKKYYNEMREAVVNLLNEENVQYKMRKSFVKKEIRILYKELFKNDKAFLRKVTKQLNDKKSFNYHTIKYFFVKNILLYIELPSENEEVNNNVYDYIRKEEIQKGTPKQEIEYLIKTRSKEDLEQLKKNVSDILNRFYSVDRGGDNNKYIYKAMKNKNALEEQLKNMKGIDINKLKDIELQMEAIETCLYKIQKVFEESLIVDIFEMNEDGKEYSILEHRALKQPSFEYAKEKFFSYIDIYENIKDKLSESSRTFFKYVFGYIILEFKRRGHDDVELFDYIKDETNFIEFYNKNIPDTENPNYIENATDKKYDLPNEKIVHKAIAFITDYLDIAYDTGRKHKNVVLKEMYKTIKSENTGLRYFRRFLEEDFLQ
>NZ_LT906446.1|WP_027890304.1|2140797_2142447_+|hypothetical-protein
MLNSVGAILLDTRSIQKYVFSCNRLKTNIGASFLVDSIFSDLMVNKILPSLNLKMPEFSWNEVDNVQMLEDDSIECEVAYIGGGNMIILVRKQDEDVIELCKKIVGSWSKEILIKAPGLKTGAAIGMLDIDSEHFQKSLGILYKQLKDNQNTILPQVDVPYVGFTLECDYSGKTAEYLRGRVEDSIINEFDNKMVSAEIVAKSSAYNVATEKLKEEYKDILGNRFDFVTKFDNLGYKDNESYISVVHIDGNNMGIKFASCKNMQERKKLSLRTAQIVKRGFYKLLKSVVIDFKEGIYDKSLNINKMKNRYLPIRPIIIGGDDITFVCPGRLGLEYAKRFIQFVSKEQLLDEKLYSNAQSYAGKIFNNQNIKVNNNMSCCAGVAIVPAKYPFYRAYELAEQLCGSAKKKSREDDESFVDFAILHGDMSPTLDQLCVQQYEAPEGYLHYGPYCITQEQNDKSNINDLFSLIEKIKKVPNNKIKDLRNVLNEDNHSIVRFLENCPEVENILKDELQKEDVGASDLWQYMKNEKILKTRYVDAIELIDFSLKV
>NZ_LT906446.1|WP_051177624.1|2142466_2143108_+|hypothetical-protein
MEKFKIKIVAKSSLQLSTNKSDITVDTEVVHDQYGMPYFPAKRFKGLLYESALEMAEISQEKWITIKDINDLFGLGNTESKIRMENFYLPNYKQMCRDWQYLNSQYKGIFTKQSVLELYTDIRFQTAIDRETGTAKATSLYNMQVINDGTTFEGEIELVEDTEKNLLILILALKNLRFVGAKRNRGYGEITCIWDSNKDRYNKVFDEFKNGII
>NZ_LT906446.1|WP_027890305.1|2143125_2144679_+|hypothetical-protein
MKKIEYIIETLAPVSLAEKNNDNTLYVTKKYIPGSIIRGMLAGKFIKYKNLINAHEDEEFFNIFLSGKVRFLSAYPVGKNLKFLKKGFSPMNIPLSLVCSKDGKSIKDISLNKQITPGYKKMNGFILKDNNEICKVDVNTQVELHMARNSDKLRLIGSNKDGRIFNYEYIEPNQFFKGYMIIDDDVVDCIEDFLDSIDLTNIHIGRSKNIQYGKCSCKMGKSLDCDIFKYNLSNKNVYLQAITPYIPIKEWQSVDEVVSSLLSDIEKQLKKVGFNVNIKKENISILSTCEEISGYVNVWQSMRERKVAISAGSLIEFIIDKMDTDILKNLSEILYSGLGCRYEEGFGQFRIWQSMDDIKIVDYPTEVISRDNISDEVRKNAREIIHRRIILEVRKKAIMDAEKINPLKSKNVLNRIERILLSNYKEETIKQEISEFKSIAKDNLRKIRLNGITMYDFLFKDLKMPYDDIKWEKYLELDGNKIELLKNDLGYNVFDIDKNILFKEYWLWFVKHLKKRN
>NZ_LT906446.1|WP_027890306.1|2144706_2146137_+|hypothetical-protein
MDNEAKIIKKIVFPNVPIKVKSPLRISTGKNDGIIDMLILKDNHGQAFIPGTSIIGVLRNYIYDIYGEKIEDVIFGNVKNNSESQSLIRVGDVKLENVKIIHRDGVAIDDITNVSKNKAKYDFEMIDRGAEGLLNIEITVRKKFENIDIDEVAKTIAYILDNGMSIGALTTKGYGKIQTKKKPTPYYIFDFNNEADSWAWLDYLDGKINKKPVKYENVRTNISNEFTMRIGLSLNSAIMIADTNVQEDLTKKSSIKIRAVQMKNGDDYVIPGTSIKGVIRNRAINILRYLSNYNEEKVISFIDDLMGHGKKVDKDGNNKLLRSRLYVNEIYLRKNNFVSAKQPRTRIDSFTGGVFYGNLFGDEPIWQIDKSKTMISINLRIRKCTEAEAGLMLLILKDLWLGNLAIGGGKSIGRGTFKGNNCLIKYQGNTFRIERVNDDDDKNRNKIKIEKDGCEEDVQDVLERYVKVLCGEFYGK
>NZ_LT906446.1|WP_155909578.1|2146099_2146702_+|TIGR03984-family-CRISPR-associated-protein
MLKFCVVNSMENSFFDKDNCLRYENRYSIKKEYVYDKKISLNDILEKVAVNDYKVLIQNVNEMKFGYYRDKHFIFNDGSDVVPKYLIQMRLFNEIEEILVLSNKEEYYLRVIKDEMNGESKLIETVDSISVLFGKLDKDENLLDGFVELYDAGRKIRKVIPSSIKSDYYALTTRSYIEYNKKTGQAGYGYYRYVDIKPEK
>NZ_LT906446.1|WP_027890307.1|2146796_2148581_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MGKNISDLKEQARAPYNFIQLNDVIVPSKINEYVEKEQLKNNKLNYWNKNDKKILNEAGYKAFIKDSAKYSGYFDVDIENITPLYFGGENGALIDGIHNAIPGSSLRGCLKNIFRIITNSAMRCNENGNFSDRLFFWRSISEDDLFTEEYLNEMSLQGKNRPRAQAGFLIEFMGKKYVCPAKFKVIKNTTNIKKVEKSPRIIWRNDCVDVFSGNIDEKDKLYFYRITEPVWDKRIAISDRFMNFYKLDQNRNSKNLFKFEGNSFSNVPRGIKLLEYALKKRYKVINPCFYCIENGKVCHLGSSPYYRIPYKKTVDMHVPSELKIPVIDFTDAVFGNKEYWGSRIYVDDCYLKDEGKKEIFYKGFNLSVKSPNPAAYQFYLNTDDDGTSVQNWNGDTNIRGYKMYWHKKMDWKGIQKDDVNKRYNGVLIKKPFRERCHFKGRVRFENLDEVELGALVYLFKLGEENCCYKLGMGKSVGLGSVKILADLYLRDDKYYTRLFDGCEKFKEYSLIEDTQKYVEEFNQYMYKYLMSHSKKSLDLYQKRMNDLRIIMGIENIDNSKWCKKISYMDINNDIDKEILRKKIPLPTIAEIAQK
>NZ_LT906446.1|WP_027890308.1|2148669_2149242_-|cytidylate-kinase-like-family-protein
MIITIGRQYGAGGREIAEKLAKKLQIPLYDRKLVAFISAHLEKGVGLDELDLTYANLYGSVSPYETMFADLNVEDDNYLFTPQSKAIRALAQKNSGIFIGRCTNFILKDFDNAYHFFIAADDEYRQERGIKVYHKSLKELKKEDAKRASYYNYYTSQNWGDPVDYDMVINAGKCGIDKAVDVICNYIQSK

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT906446_1	1.11\|556471\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556471-556505	35	NZ_LT906446.1	1878774-1878808	0	1.0
NZ_LT906446_6	6.10\|2123465\|36\|NZ_LT906446\|CRT	2123465-2123500	36	NZ_LT906446.1	526159-526194	0	1.0
NZ_LT906446_8	8.1\|2131119\|36\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	2131119-2131154	36	NZ_LT906446.1	358555-358590	0	1.0
NZ_LT906446_8	8.4\|2131312\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	2131312-2131346	35	NZ_LT906446.1	678725-678759	2	0.943

1. spacer 1.11|556471|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to position: 1878774-1878808, mismatch: 0, identity: 1.0

aaagcagcttatgtaacaggtacagcacttcttgc	CRISPR spacer
aaagcagcttatgtaacaggtacagcacttcttgc	Protospacer
***********************************

2. spacer 6.10|2123465|36|NZ_LT906446|CRT matches to position: 526159-526194, mismatch: 0, identity: 1.0

gaaacatttaaatgtagctataaaatagaaattctt	CRISPR spacer
gaaacatttaaatgtagctataaaatagaaattctt	Protospacer
************************************

3. spacer 8.1|2131119|36|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to position: 358555-358590, mismatch: 0, identity: 1.0

gcatgaaagcccattttatgatgaagatgcttttgc	CRISPR spacer
gcatgaaagcccattttatgatgaagatgcttttgc	Protospacer
************************************

4. spacer 8.4|2131312|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to position: 678725-678759, mismatch: 2, identity: 0.943

tcaaaagaaccaagttttcttacttgattgagttg	CRISPR spacer
tcaaaagaaccaagttttctcacttgattaagttg	Protospacer
********************.********.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT906446_1	1.28\|557591\|36\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557591-557626	36	HG796856	Uncultured bacterium plasmid pRGF00250	676-711	0	1.0
NZ_LT906446_3	3.3\|733392\|37\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	733392-733428	37	NZ_CP048628	Megamonas funiformis strain JCM 14723 plasmid putative_Mfuni1, complete sequence	41600-41636	2	0.946
NZ_LT906446_1	1.21\|557130\|36\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557130-557165	36	HG796412	Uncultured bacterium plasmid pRGI00992	735-770	6	0.833
NZ_LT906446_4	4.1\|1166412\|27\|NZ_LT906446\|CRT	1166412-1166438	27	MF417885	Uncultured Caudovirales phage clone 3S_9, partial genome	7214-7240	6	0.778
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	247573-247606	8	0.765
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	830060-830093	8	0.765
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	830075-830108	8	0.765
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	283192-283225	8	0.765
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	431363-431396	8	0.765
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	549645-549678	8	0.765
NZ_LT906446_1	1.21\|557130\|36\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557130-557165	36	AP013454	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S33-C36	15066-15101	8	0.778
NZ_LT906446_2	2.10\|659462\|34\|NZ_LT906446\|CRISPRCasFinder,CRT	659462-659495	34	HG796317	Uncultured bacterium plasmid pRGI00402	2159-2192	8	0.765
NZ_LT906446_2	2.13\|659464\|32\|NZ_LT906446\|PILER-CR	659464-659495	32	HG796317	Uncultured bacterium plasmid pRGI00402	2161-2192	8	0.75
NZ_LT906446_8	8.3\|2131248\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	2131248-2131282	35	MH617498	Microviridae sp. isolate ctcb690, complete genome	103-137	8	0.771
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	AP013441	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22-MedDCM-OCT-S33-C34	14482-14515	9	0.735
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	MN694159	Marine virus AFVG_250M1044, complete genome	25587-25620	9	0.735
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NC_014508	Enterococcus faecalis plasmid pEF-01, complete sequence	10546-10580	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP012757	Staphylococcus aureus subsp. aureus strain JS395 plasmid, complete sequence	4984-5018	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP037957	Enterococcus hirae strain CQP3-9 plasmid pCQP3-9_2, complete sequence	7729-7763	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038162	Enterococcus faecium strain GZ8 plasmid pGZ8, complete sequence	26417-26451	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	MT074685	Enterococcus faecium strain T-E1077-31 plasmid pT-E1077-31, complete sequence	8138-8172	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	MT074685	Enterococcus faecium strain T-E1077-31 plasmid pT-E1077-31, complete sequence	27949-27983	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	MT074684	Enterococcus faecium strain E1077 plasmid pE1077-23, complete sequence	8146-8180	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_MH784601	Enterococcus faecium strain 25 plasmid pC25-1, complete sequence	35494-35528	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_MH784602	Enterococcus faecium strain 27 plasmid pC27-2, complete sequence	30202-30236	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_MK140642	Enterococcus faecalis strain E076 plasmid pE076, complete sequence	19742-19776	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_KX274135	Staphylococcus arlettae strain SA-01 plasmid pSA-01, complete sequence	47453-47487	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	MK798157	Enterococcus hirae strain fas4 plasmid pfas4-1, complete sequence	18032-18066	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	MN831412	Enterococcus faecalis strain M18/0011 plasmid pM18/0011, complete sequence	1355-1389	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038165	Enterococcus faecium strain HB2-2 plasmid pHB2-2, complete sequence	10226-10260	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038167	Enterococcus faecium strain SC3-1 plasmid pSC3-1, complete sequence	25218-25252	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038171	Enterococcus faecium strain SDGJP3 plasmid pSDGJP3, complete sequence	37812-37846	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038169	Enterococcus faecium strain SCBC1 plasmid pSCBC1, complete sequence	13058-13092	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038176	Enterococcus faecium strain HN11 plasmid pHN11, complete sequence	68245-68279	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_CP038173	Enterococcus faecium strain YN2-1 plasmid pYN2-1, complete sequence	17906-17940	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_MK140641	Enterococcus faecalis strain E035 plasmid pE035, complete sequence	36225-36259	9	0.743
NZ_LT906446_1	1.29\|557657\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557657-557691	35	NZ_MK861852	Enterococcus faecalis strain C10 plasmid pC10, complete sequence	18986-19020	9	0.743
NZ_LT906446_1	1.31\|557788\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	557788-557822	35	NC_017966	Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence	439669-439703	9	0.743
NZ_LT906446_2	2.3\|659002\|34\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659002-659035	34	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	41778-41811	9	0.735
NZ_LT906446_2	2.3\|659002\|34\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659002-659035	34	NZ_CP021643	Campylobacter concisus strain P2CDO4 plasmid pICON, complete sequence	13204-13237	9	0.735
NZ_LT906446_4	4.5\|1166671\|34\|NZ_LT906446\|CRT,CRISPRCasFinder,PILER-CR	1166671-1166704	34	NC_015938	Salmonella phage 7-11, complete genome	36559-36592	9	0.735
NZ_LT906446_4	4.5\|1166671\|34\|NZ_LT906446\|CRT,CRISPRCasFinder,PILER-CR	1166671-1166704	34	MG873442	Salmonella phage SE131, complete genome	54348-54381	9	0.735
NZ_LT906446_8	8.2\|2131184\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	2131184-2131218	35	KJ018210	Flavobacterium sp. phage 1/32, complete genome	33148-33182	9	0.743
NZ_LT906446_8	8.2\|2131184\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	2131184-2131218	35	GU071101	Prochlorococcus phage P-HM1, complete genome	161922-161956	9	0.743
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	39718-39751	10	0.706
NZ_LT906446_1	1.8\|556275\|34\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556275-556308	34	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	436388-436421	10	0.706
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	116568-116603	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	NC_027364	Escherichia phage PBECO 4, complete genome	271839-271874	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	MH383160	Escherichia phage UB, complete genome	336906-336941	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	MK327931	Escherichia phage vB_EcoM_G17, complete genome	142054-142089	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	LC494302	Escherichia phage SP27 DNA, complete genome	12786-12821	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	301297-301332	10	0.722
NZ_LT906446_2	2.5\|659132\|36\|NZ_LT906446\|CRISPRCasFinder,CRT,PILER-CR	659132-659167	36	KM507819	Escherichia phage 121Q, complete genome	12813-12848	10	0.722
NZ_LT906446_3	3.5\|733525\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	733525-733559	35	NC_009927	Acaryochloris marina MBIC11017 plasmid pREB2, complete sequence	140162-140196	10	0.714
NZ_LT906446_3	3.5\|733525\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	733525-733559	35	NC_027120	Lactococcus phage 1358, complete sequence	26859-26893	10	0.714
NZ_LT906446_3	3.6\|733590\|36\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	733590-733625	36	CP054911	Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence	94981-95016	11	0.694

1. spacer 1.28|557591|36|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to HG796856 (Uncultured bacterium plasmid pRGF00250) position: , mismatch: 0, identity: 1.0

gcttgaaattttcgttgcggttttgatgctaaaatt	CRISPR spacer
gcttgaaattttcgttgcggttttgatgctaaaatt	Protospacer
************************************

2. spacer 3.3|733392|37|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP048628 (Megamonas funiformis strain JCM 14723 plasmid putative_Mfuni1, complete sequence) position: , mismatch: 2, identity: 0.946

gcgaacttggatagtatctatctatcttttgcactat	CRISPR spacer
gcgagcttggatagtatctatctatcttttgcactac	Protospacer
****.*******************************.

3. spacer 1.21|557130|36|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to HG796412 (Uncultured bacterium plasmid pRGI00992) position: , mismatch: 6, identity: 0.833

ctgagtaaaaagtattgattttattgggtttgtggc	CRISPR spacer
ttttagaaaaagtattgattttattggttttgtggc	Protospacer
.*  . ********************* ********

4. spacer 4.1|1166412|27|NZ_LT906446|CRT matches to MF417885 (Uncultured Caudovirales phage clone 3S_9, partial genome) position: , mismatch: 6, identity: 0.778

tggtataaataataccagtttattttt	CRISPR spacer
ctgtataagtaataccagttgatttac	Protospacer
. ******.*********** **** .

5. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

6. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

7. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

8. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

9. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

10. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 8, identity: 0.765

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
aaacaaaaattaatttcattttcttttatttcat	Protospacer
 .*  **** .*******************.* *

11. spacer 1.21|557130|36|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to AP013454 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S33-C36) position: , mismatch: 8, identity: 0.778

ctgagtaaaaagtattgattttattgggtttgtggc	CRISPR spacer
caacactaaaagtattggttttattaggtttgtggc	Protospacer
* . .. **********.*******.**********

12. spacer 2.10|659462|34|NZ_LT906446|CRISPRCasFinder,CRT matches to HG796317 (Uncultured bacterium plasmid pRGI00402) position: , mismatch: 8, identity: 0.765

ttatcaaaaaaatcaaaaaactggggggttaatt	CRISPR spacer
ttcggagaaaaatctaaaatctggggggttacta	Protospacer
**   *.******* **** *********** *

13. spacer 2.13|659464|32|NZ_LT906446|PILER-CR matches to HG796317 (Uncultured bacterium plasmid pRGI00402) position: , mismatch: 8, identity: 0.75

atcaaaaaaatcaaaaaactggggggttaatt	CRISPR spacer
cggagaaaaatctaaaatctggggggttacta	Protospacer
   *.******* **** *********** *

14. spacer 8.3|2131248|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MH617498 (Microviridae sp. isolate ctcb690, complete genome) position: , mismatch: 8, identity: 0.771

tcaacataaatcgggataagatagccagtgtcgaa	CRISPR spacer
tccacataaatcgggataagataacccgcattcat	Protospacer
** ********************.** *..*. *

15. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to AP013441 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-C22-MedDCM-OCT-S33-C34) position: , mismatch: 9, identity: 0.735

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
agttttcagtcaatttcattttcatttactcctt	Protospacer
 *  *  *. ************* ****.*****

16. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MN694159 (Marine virus AFVG_250M1044, complete genome) position: , mismatch: 9, identity: 0.735

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
ttttgtaaagcaatttcattttgttttgtttgtt	Protospacer
*     **************** ****.**. **

17. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NC_014508 (Enterococcus faecalis plasmid pEF-01, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

18. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012757 (Staphylococcus aureus subsp. aureus strain JS395 plasmid, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

19. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037957 (Enterococcus hirae strain CQP3-9 plasmid pCQP3-9_2, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

20. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038162 (Enterococcus faecium strain GZ8 plasmid pGZ8, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

21. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MT074685 (Enterococcus faecium strain T-E1077-31 plasmid pT-E1077-31, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

22. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MT074685 (Enterococcus faecium strain T-E1077-31 plasmid pT-E1077-31, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

23. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MT074684 (Enterococcus faecium strain E1077 plasmid pE1077-23, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

24. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH784601 (Enterococcus faecium strain 25 plasmid pC25-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

25. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH784602 (Enterococcus faecium strain 27 plasmid pC27-2, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

26. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK140642 (Enterococcus faecalis strain E076 plasmid pE076, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

27. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX274135 (Staphylococcus arlettae strain SA-01 plasmid pSA-01, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

28. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MK798157 (Enterococcus hirae strain fas4 plasmid pfas4-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

29. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to MN831412 (Enterococcus faecalis strain M18/0011 plasmid pM18/0011, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

30. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038165 (Enterococcus faecium strain HB2-2 plasmid pHB2-2, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

31. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038167 (Enterococcus faecium strain SC3-1 plasmid pSC3-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

32. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038171 (Enterococcus faecium strain SDGJP3 plasmid pSDGJP3, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

33. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038169 (Enterococcus faecium strain SCBC1 plasmid pSCBC1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

34. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038176 (Enterococcus faecium strain HN11 plasmid pHN11, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

35. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038173 (Enterococcus faecium strain YN2-1 plasmid pYN2-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

36. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK140641 (Enterococcus faecalis strain E035 plasmid pE035, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

37. spacer 1.29|557657|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK861852 (Enterococcus faecalis strain C10 plasmid pC10, complete sequence) position: , mismatch: 9, identity: 0.743

ttttttaaattatttaattgttcttgagctgattt	CRISPR spacer
tttttaaaattatttagttgttcttgctattaaca	Protospacer
***** **********.*********   * * .

38. spacer 1.31|557788|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NC_017966 (Tistrella mobilis KA081020-065 plasmid pTM2, complete sequence) position: , mismatch: 9, identity: 0.743

cccaaatttccgtttccgcctgcccacgctcggct	CRISPR spacer
cccggtcgaccgctaccgcctgcccacgctcggcg	Protospacer
***.. .  ***.* *******************

39. spacer 2.3|659002|34|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

ttgtatttggttctacatttgtttttggatctac	CRISPR spacer
ttggatttggttctatatttgttttgatacttta	Protospacer
*** ***********.********* . *..*

40. spacer 2.3|659002|34|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021643 (Campylobacter concisus strain P2CDO4 plasmid pICON, complete sequence) position: , mismatch: 9, identity: 0.735

ttgtatttggttctacatttgtttttggatctac	CRISPR spacer
tgccgcttggttctccatttgtttttgtatattc	Protospacer
*  ...******** ************ ** * *

41. spacer 4.5|1166671|34|NZ_LT906446|CRT,CRISPRCasFinder,PILER-CR matches to NC_015938 (Salmonella phage 7-11, complete genome) position: , mismatch: 9, identity: 0.735

ccgataaaactattataaaaaatcaccctcttgt	CRISPR spacer
taggtgattatattattaaaaatcaccctcatgt	Protospacer
. *.*.*   ****** ************* ***

42. spacer 4.5|1166671|34|NZ_LT906446|CRT,CRISPRCasFinder,PILER-CR matches to MG873442 (Salmonella phage SE131, complete genome) position: , mismatch: 9, identity: 0.735

ccgataaaactattataaaaaatcaccctcttgt	CRISPR spacer
taggtgattatattattaaaaatcaccctcatgt	Protospacer
. *.*.*   ****** ************* ***

43. spacer 8.2|2131184|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to KJ018210 (Flavobacterium sp. phage 1/32, complete genome) position: , mismatch: 9, identity: 0.743

taaagttttttctattgtttcaaatttaacctcac	CRISPR spacer
aaaagttttttccattgttttaaattttagggtaa	Protospacer
 ***********.*******.****** *   .*

44. spacer 8.2|2131184|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to GU071101 (Prochlorococcus phage P-HM1, complete genome) position: , mismatch: 9, identity: 0.743

taaagttttttctattgtttcaaatttaacctcac	CRISPR spacer
tattgttttttctattgcttcacatttaattacct	Protospacer
**  *************.**** ******.. * .

45. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 10, identity: 0.706

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
actgtataagcaatttcattttcttttcttttaa	Protospacer
   .** ******************** **..

46. spacer 1.8|556275|34|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 10, identity: 0.706

tgaataaaagcaatttcattttcttttattcctt	CRISPR spacer
ccggcaatatcaatttcattttcttttattttat	Protospacer
. ...** * ********************.. *

47. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

48. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

49. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

50. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

51. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

52. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

53. spacer 2.5|659132|36|NZ_LT906446|CRISPRCasFinder,CRT,PILER-CR matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 10, identity: 0.722

attgattaacaaaataagtgctaataagttttttaa	CRISPR spacer
gcttgctcctaaaaaaagtactaataagttttttaa	Protospacer
..* ..*  .**** ****.****************

54. spacer 3.5|733525|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NC_009927 (Acaryochloris marina MBIC11017 plasmid pREB2, complete sequence) position: , mismatch: 10, identity: 0.714

gttgtatcagtcaaagaaattaacatcttgatgac	CRISPR spacer
ttgctatcagtcaaagaaaccaacatcttccaagc	Protospacer
 *  ***************..********   ..*

55. spacer 3.5|733525|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NC_027120 (Lactococcus phage 1358, complete sequence) position: , mismatch: 10, identity: 0.714

gttgtatcagtcaaagaaattaacatcttgatgac	CRISPR spacer
ggcacgaaaatcgaagaaattaacaacttgatgac	Protospacer
* ....  *.**.************ *********

56. spacer 3.6|733590|36|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to CP054911 (Pantoea ananatis strain FDAARGOS_680 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.694

ttggatgttgcataatttatattattaattccccat	CRISPR spacer
tataatgttgcataatttatattatggattaaatgc	Protospacer
*  .********************* .***   ...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

283739 : 342502

Geobacillus_virus(20.0%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095197715.1\|283739_284849_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	1.2e-89	46.4
WP_027890653.1\|285100_285676_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_027890652.1\|285681_286356_+	hypothetical protein	NA	NA	NA	NA
WP_027890651.1\|286377_287643_+	SLC13/DASS family transporter	Q6A201	Oenococcus_phage	3.5e-48	33.0
WP_027890650.1\|287990_288284_+	OadG family protein	NA	NA	NA	NA
WP_027890649.1\|288316_289435_+	sodium ion-translocating decarboxylase subunit beta	NA	NA	NA	NA
WP_169449332.1\|289475_289643_+	hypothetical protein	NA	NA	NA	NA
WP_027890648.1\|291226_292387_+	hypothetical protein	NA	NA	NA	NA
WP_095197672.1\|292370_302144_+	YadA-like family protein	NA	NA	NA	NA
WP_027890680.1\|302233_302656_+	DUF3887 domain-containing protein	NA	NA	NA	NA
WP_157738438.1\|302715_303144_+	hypothetical protein	NA	NA	NA	NA
WP_095197674.1\|303258_303765_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_157738439.1\|303719_304613_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.5e-77	56.1
WP_036254880.1\|304730_306251_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.7e-20	29.9
WP_027890562.1\|306380_307346_-	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_027890561.1\|307574_308348_+	ribonuclease HII	A0A0N9QYD4	Chrysochromulina_ericina_virus	5.8e-22	40.2
WP_027890560.1\|308359_308719_+	YraN family protein	NA	NA	NA	NA
WP_036254878.1\|308718_309303_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_027890558.1\|309332_310862_+	YifB family Mg chelatase-like AAA ATPase	NA	NA	NA	NA
WP_027890557.1\|310876_311734_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_036254876.1\|311828_313106_+	type II/IV secretion system protein	NA	NA	NA	NA
WP_027890555.1\|313083_314100_+	PilT/PilU family type 4a pilus ATPase	NA	NA	NA	NA
WP_027890554.1\|314101_315325_+	type II secretion system F family protein	NA	NA	NA	NA
WP_036254875.1\|315341_315746_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_036254874.1\|315757_316225_+	prepilin peptidase	NA	NA	NA	NA
WP_027890552.1\|316232_316676_+	hypothetical protein	NA	NA	NA	NA
WP_027890551.1\|316672_317053_+	hypothetical protein	NA	NA	NA	NA
WP_051177645.1\|317039_317597_+	hypothetical protein	NA	NA	NA	NA
WP_027890549.1\|317586_318033_+	hypothetical protein	NA	NA	NA	NA
WP_027890548.1\|318121_318883_+	hypothetical protein	NA	NA	NA	NA
WP_095197716.1\|319469_320579_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	6.7e-88	45.6
WP_157738440.1\|320763_321012_+	PilN domain-containing protein	NA	NA	NA	NA
WP_027890603.1\|321013_321547_+	type 4a pilus biogenesis protein PilO	NA	NA	NA	NA
WP_027890604.1\|321627_322449_+	TIGR00159 family protein	NA	NA	NA	NA
WP_027890605.1\|322445_323417_+	hypothetical protein	NA	NA	NA	NA
WP_027890606.1\|323431_325030_+	hypothetical protein	NA	NA	NA	NA
WP_027890607.1\|325056_326277_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	9.8e-32	26.5
WP_027890608.1\|326338_327592_-	serine/threonine transporter SstT	NA	NA	NA	NA
WP_027890609.1\|327784_328906_-	glycerate kinase	W6LM47	Streptococcus_phage	1.3e-43	38.0
WP_027890610.1\|329284_329725_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_008538697.1\|329748_330138_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_036254899.1\|330278_331604_+	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_036254902.1\|331717_332878_+	MFS transporter	NA	NA	NA	NA
WP_095197676.1\|333031_333973_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.7e-84	52.7
WP_027890642.1\|334223_335519_+	L-fucose:H+ symporter permease	NA	NA	NA	NA
WP_027890643.1\|335544_336570_+	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_027890644.1\|336596_337469_+	ribokinase	NA	NA	NA	NA
WP_027890645.1\|337672_338692_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_027890646.1\|338734_339877_-	carboxynorspermidine decarboxylase	NA	NA	NA	NA
WP_027890647.1\|340300_341254_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_157738441.1\|341608_342502_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.6e-76	55.3

DBSCAN-SWA_2

902716 : 912083

Prochlorococcus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095197685.1\|902716_905560_+	DEAD/DEAH box helicase	Q5YA94	Bacillus_phage	8.1e-29	29.9
WP_027890719.1\|905641_906913_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_027890720.1\|906998_907592_-	hypothetical protein	E3SNU8	Prochlorococcus_phage	1.5e-49	55.6
WP_027890721.1\|907616_908228_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	9.5e-28	40.2
WP_027890722.1\|908220_909288_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-67	43.7
WP_027890723.1\|909322_910756_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.4e-68	35.6
WP_027890724.1\|910816_911530_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	9.4e-43	39.7
WP_027890725.1\|911591_912083_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	5.1e-24	44.7

DBSCAN-SWA_3

1355298 : 1368190

Staphylococcus_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027889849.1\|1355298_1356672_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.1e-92	40.3
WP_027889850.1\|1357008_1358934_+	N-6 DNA methylase	A0A1W6JNK1	Staphylococcus_phage	9.6e-34	30.5
WP_027889851.1\|1358923_1360045_+	restriction endonuclease subunit S	A0A1W6JNN3	Staphylococcus_phage	7.6e-07	24.8
WP_027889852.1\|1360158_1361142_+	lactate dehydrogenase	Q89388	Paramecium_bursaria_Chlorella_virus	2.8e-45	34.7
WP_027889853.1\|1361210_1361711_+	nitroreductase family protein	A0A1V0E011	Clostridioides_phage	5.2e-24	34.6
WP_027889854.1\|1361762_1363034_-	uracil permease	Q9KX94	Enterobacteria_phage	1.3e-66	37.1
WP_027889855.1\|1363162_1363636_+	nucleoside deaminase	S4VYZ2	Pandoravirus	1.0e-16	37.2
WP_051177592.1\|1363696_1364083_-	thioesterase family protein	NA	NA	NA	NA
WP_027889857.1\|1364149_1364860_-	ribonuclease III	J2YAN1	Acanthamoeba_polyphaga_lentillevirus	9.4e-27	34.2
WP_027889858.1\|1364870_1366112_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_027889859.1\|1366128_1367073_-	nitronate monooxygenase	NA	NA	NA	NA
WP_027889860.1\|1367159_1367390_-	acyl carrier protein	B2ZXV3	Ralstonia_phage	1.1e-08	42.3
WP_027889861.1\|1367446_1368190_-	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	4.1e-25	36.6

DBSCAN-SWA_4

1376906 : 1384187

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027889872.1\|1376906_1377371_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.7e-46	70.9
WP_027889873.1\|1377449_1378649_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.4e-104	49.1
WP_027889874.1\|1378664_1379321_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.6e-36	39.9
WP_027889875.1\|1379333_1380428_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.5e-47	33.7
WP_027889876.1\|1380733_1381540_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_081654843.1\|1381734_1382712_+	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	6.9e-12	25.0
WP_071601704.1\|1382726_1383128_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_027889878.1\|1383174_1383381_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_027889879.1\|1383392_1384187_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	2.7e-22	32.4

DBSCAN-SWA_5

1822837 : 1892819

Streptococcus_phage(16.67%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_027890472.1\|1822837_1823713_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_027890473.1\|1823744_1824428_-	TerC family protein	W8EBD0	Pseudomonas_phage	6.0e-31	42.1
WP_027890474.1\|1824645_1825611_-	bile acid:sodium symporter family protein	NA	NA	NA	NA
WP_027890475.1\|1825847_1826369_-	nitroreductase	NA	NA	NA	NA
WP_036254841.1\|1826438_1826618_-	hypothetical protein	NA	NA	NA	NA
WP_027890476.1\|1826733_1829070_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_027890477.1\|1829092_1830724_-	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_027890478.1\|1830711_1831818_-	glutamate synthase	NA	NA	NA	NA
WP_036254843.1\|1832229_1832967_-	hypothetical protein	NA	NA	NA	NA
WP_027890479.1\|1832984_1833374_-	DUF3783 domain-containing protein	NA	NA	NA	NA
WP_027890480.1\|1833527_1834580_-	DUF2939 domain-containing protein	NA	NA	NA	NA
WP_027890481.1\|1834806_1835208_+	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_027890482.1\|1835244_1836621_-	amino acid permease	NA	NA	NA	NA
WP_027890483.1\|1836819_1837455_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	2.1e-38	41.1
WP_027890484.1\|1837510_1838599_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	8.3e-91	47.2
WP_027890485.1\|1838915_1839410_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	9.3e-50	62.0
WP_027890486.1\|1839430_1840003_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_027890487.1\|1840029_1841583_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_095197670.1\|1841728_1842193_-\|transposase	IS200/IS605 family transposase	Q331U4	Clostridium_botulinum_C_phage	1.6e-11	32.3
WP_027890678.1\|1842376_1843762_-	amino acid permease	NA	NA	NA	NA
WP_027890677.1\|1843858_1844980_-	alanine dehydrogenase	NA	NA	NA	NA
WP_027890685.1\|1850852_1851956_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_157738446.1\|1852309_1853203_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	9.5e-77	55.3
WP_095197703.1\|1853157_1853664_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_027890669.1\|1853750_1855748_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	3.4e-151	47.6
WP_027890668.1\|1856014_1857364_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_095197670.1\|1857513_1857978_-\|transposase	IS200/IS605 family transposase	Q331U4	Clostridium_botulinum_C_phage	1.6e-11	32.3
WP_027889004.1\|1858152_1861119_-	type III restriction-modification system endonuclease	Q71TG1	Escherichia_phage	7.9e-136	35.1
WP_027889005.1\|1861130_1863002_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	2.3e-112	46.8
WP_027889006.1\|1863147_1863795_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_027889007.1\|1864007_1865018_-	hydrogenase expression/formation protein HypE	NA	NA	NA	NA
WP_027889008.1\|1865036_1866137_-	hydrogenase formation protein HypD	NA	NA	NA	NA
WP_027889009.1\|1866084_1866351_-	HypC/HybG/HupF family hydrogenase formation chaperone	NA	NA	NA	NA
WP_027889010.1\|1866369_1868658_-	carbamoyltransferase HypF	NA	NA	NA	NA
WP_027889011.1\|1868633_1869110_-	HyaD/HybD family hydrogenase maturation endopeptidase	NA	NA	NA	NA
WP_027889012.1\|1869111_1869786_-	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_027889013.1\|1869785_1870127_-	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_027889014.1\|1870177_1870420_-	cation transporter	NA	NA	NA	NA
WP_036254133.1\|1870434_1871172_-	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_027889016.1\|1871164_1873069_-	nickel-dependent hydrogenase large subunit	NA	NA	NA	NA
WP_027889017.1\|1873075_1874176_-	hydrogenase small subunit	NA	NA	NA	NA
WP_051177508.1\|1874538_1875411_-	YitT family protein	NA	NA	NA	NA
WP_027889019.1\|1875605_1876349_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_027889020.1\|1876349_1877258_+	1-phosphofructokinase	NA	NA	NA	NA
WP_027889021.1\|1877276_1879208_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_027889022.1\|1879568_1879910_+	STAS domain-containing protein	NA	NA	NA	NA
WP_027889023.1\|1879928_1882025_+	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_027889024.1\|1882045_1882420_+	desulfoferrodoxin	NA	NA	NA	NA
WP_027889025.1\|1882462_1883410_-	D-2-hydroxyacid dehydrogenase	M1I636	Acanthocystis_turfacea_Chlorella_virus	2.1e-13	29.5
WP_027889026.1\|1883423_1884710_-	M18 family aminopeptidase	NA	NA	NA	NA
WP_027889027.1\|1884835_1885381_-	NADH peroxidase	NA	NA	NA	NA
WP_051177510.1\|1885747_1886182_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_027889028.1\|1886174_1887329_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_027889029.1\|1887459_1888410_+	YybS family protein	NA	NA	NA	NA
WP_027889030.1\|1888421_1890434_+	DHH family phosphoesterase	NA	NA	NA	NA
WP_027889031.1\|1890405_1890849_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_027889032.1\|1890860_1892819_+\|protease	ATP-dependent protease, Lon family	A0A0R6PGP8	Moraxella_phage	1.6e-28	25.4

Anti-CRISPR protein detection

Acr_ID: NZ_LT906446.1|WP_027889031.1|1890405_1890849_+|50S-ribosomal-protein-L9

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LT906446.1|WP_027889031.1|1890405_1890849_+|50S-ribosomal-protein-L9

1890405_1890849_+

147 aa aa

1822837-1892819

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_LT906446_1	Orphan	1.11\|556471\|35\|NZ_LT906446\|PILER-CR,CRISPRCasFinder,CRT	556471-556505	35	1878774-1878808	0

1. spacer 1.11|556471|35|NZ_LT906446|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT906446 position: 1878774-1878808, mismatch: 0

aaagcagcttatgtaacaggtacagcacttcttgc	CRISPR spacer
aaagcagcttatgtaacaggtacagcacttcttgc	Protospacer
***********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LT906446

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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