CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT899687	Lactobacillus delbrueckii subsp. bulgaricus isolate Lactobacillus bulgaricus ACA-DC 87 chromosome I	3 crisprs	DEDDh,cas9,cas1,cas2,csn2,DinG,csa3,cas3,cas14j,c2c9_V-U4	3	8	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT899687_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT899687_1

297961-298038

Unclear

Consensus_repeat	Method
AAGTGTTTTCTTATCTCATACTTT	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_LT899687_1

>merge|NZ_LT899687|1|297961-298038|CRISPRCasFinder
AAGTGTTTTCTTATCTCATACTTTGGATAACCTCCGTTATGTGGATTTACATGTAAATGTTTTCTTATCTCATACTTT

>NZ_LT899687|1|1|297961-298038|CRISPRCasFinder
AAGTGTTTTCTTATCTCATACTTT	GGATAACCTCCGTTATGTGGATTTACATGT
AAATGTTTTCTTATCTCATACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT899687.1\|WP_003620772.1\|295636_296050_+\|holo-ACP-synthase	unknown	unknown	gnl\|CDD\|234610
NZ_LT899687.1\|WP_003620768.1\|292723_294091_+\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl\|CDD\|223841
NZ_LT899687.1\|WP_002878700.1\|288124_288523_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378129
NZ_LT899687.1\|WP_089119719.1\|289254_290874_+\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NZ_LT899687.1\|WP_003620764.1\|290993_292265_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_LT899687.1\|WP_003622441.1\|306983_307865_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NZ_LT899687.1\|WP_003612818.1\|302579_302960_+\|septum-formation-initiator-family-protein	unknown	unknown	gnl\|CDD\|225471
NZ_LT899687.1\|WP_003622430.1\|294100_295552_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
NZ_LT899687.1\|WP_003612856.1\|298152_298710_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NZ_LT899687.1\|WP_089119721.1\|303359_304655_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950
NZ_LT899687.1\|WP_011543628.1\|296046_297177_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NZ_LT899687.1\|WP_089119720.1\|298726_302203_+\|transcription-repair-coupling-factor	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224118
NZ_LT899687.1\|WP_002878680.1\|302271_302514_+\|RNA-binding-S4-domain-containing-protein	unknown	unknown	gnl\|CDD\|224109
NZ_LT899687.1\|WP_089119723.1\|308325_309936_+\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_LT899687.1\|WP_003620777.1\|297230_297929_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341358
NZ_LT899687.1\|WP_089119724.1\|309945_311232_+\|peptidase-T	unknown	unknown	gnl\|CDD\|237371
NZ_LT899687.1\|WP_089119722.1\|304725_306939_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|273520
NZ_LT899687.1\|WP_011678015.1\|302959_303313_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|239917
NZ_LT899687.1\|WP_003620766.1\|292364_292616_+\|type-B-50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234969
NZ_LT899687.1\|WP_003620758.1\|288568_289138_+\|DNA-directed-RNA-polymerase-subunit-delta	unknown	unknown	gnl\|CDD\|275360

Protein	Function_ID	Function_description	E-value
NZ_LT899687.1\|WP_003620772.1\|295636_296050_+\|holo-ACP-synthase	gnl\|CDD\|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	1.77441e-43
NZ_LT899687.1\|WP_003620768.1\|292723_294091_+\|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl\|CDD\|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	2.27111e-163
NZ_LT899687.1\|WP_002878700.1\|288124_288523_+\|DUF1934-domain-containing-protein	gnl\|CDD\|378129	pfam09148, DUF1934, Domain of unknown function (DUF1934). Members of this family are found in a set of hypothetical bacterial proteins. Their precise function has not, as yet, been defined.	1.69065e-19
NZ_LT899687.1\|WP_089119719.1\|289254_290874_+\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NZ_LT899687.1\|WP_003620764.1\|290993_292265_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_LT899687.1\|WP_003622441.1\|306983_307865_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	1.22323e-141
NZ_LT899687.1\|WP_003612818.1\|302579_302960_+\|septum-formation-initiator-family-protein	gnl\|CDD\|225471	COG2919, COG2919, Septum formation initiator [Cell division and chromosome partitioning].	4.68835e-09
NZ_LT899687.1\|WP_003622430.1\|294100_295552_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	8.93308e-170
NZ_LT899687.1\|WP_003612856.1\|298152_298710_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	3.31284e-94
NZ_LT899687.1\|WP_089119721.1\|303359_304655_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	2.50507e-69
NZ_LT899687.1\|WP_011543628.1\|296046_297177_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	1.3608e-148
NZ_LT899687.1\|WP_089119720.1\|298726_302203_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NZ_LT899687.1\|WP_002878680.1\|302271_302514_+\|RNA-binding-S4-domain-containing-protein	gnl\|CDD\|224109	COG1188, COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis].	1.42894e-25
NZ_LT899687.1\|WP_089119723.1\|308325_309936_+\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_LT899687.1\|WP_003620777.1\|297230_297929_-\|CBS-domain-containing-protein	gnl\|CDD\|341358	cd02205, CBS_pair_SF, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains superfamily. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.13228e-12
NZ_LT899687.1\|WP_089119724.1\|309945_311232_+\|peptidase-T	gnl\|CDD\|237371	PRK13381, PRK13381, peptidase T; Provisional.	0
NZ_LT899687.1\|WP_089119722.1\|304725_306939_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NZ_LT899687.1\|WP_011678015.1\|302959_303313_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|239917	cd04471, S1_RNase_R, S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase play an important role in the degradation of RNA with extensive secondary structure, such as rRNA, tRNA, and certain mRNA which contains repetitive extragenic palindromic sequences. The C-terminal S1 domain binds ssRNA.	2.98771e-11
NZ_LT899687.1\|WP_003620766.1\|292364_292616_+\|type-B-50S-ribosomal-protein-L31	gnl\|CDD\|234969	PRK01678, rpmE2, type B 50S ribosomal protein L31.	3.36675e-48
NZ_LT899687.1\|WP_003620758.1\|288568_289138_+\|DNA-directed-RNA-polymerase-subunit-delta	gnl\|CDD\|275360	TIGR04567, DNA-directed_RNA_polymerase_subunit_delta, DNA-directed RNA polymerase delta subunit. Members of this family are the RNA polymerase delta subunit, as found in the Firmicutes and the Mollicutes. All members of the seed alignment have an extended C-terminal low-complexity region, consisting largely of Asp and Glu, that is not included in the model. Proteins giving borderline scores should be checked to confirm a similar acidic C-terminal domain. [Transcription, DNA-dependent RNA polymerase].	2.54864e-35

>NZ_LT899687.1|WP_003620777.1|297230_297929_-|CBS-domain-containing-protein
MLIKSLVIKKDYLTTVNEHATLEEALKVLESSGYRCVPILDDSGKIFRGNIYKMHIYRHKSQGGDMSLPVTYLLKNATKTIKINAPFFQVFFTIKDLPYIAVLDTDNTFYGILTHARLLDMLSSAWNIKTGAYVLTVLSTNDSGNLTKMTKIIAKFVNLAGAMTLDAPASEFDGKYVRRTLFTLPQGTTETELKAICKKLKAKGFPVVAVEDLAAGMNIMSEEKPGVFLNEE
>NZ_LT899687.1|WP_011543628.1|296046_297177_+|alanine-racemase
MITAVNRPAALHINLAAIKENTRQAKAHLKPGQKLFCVVKANAYGHGAARLAPVMEEAGADGFCVAMLDEGLELRRAQIVKPILVLGLQPAEEAALAAANDISLPVSSLDWLKKAEKVLRKEGLQLKIHLAIDSGMGRIGFSEDEDFKAVNEYLQGNDAFFVEGMFTHFASADSADASYFDYQVKRFKHMESLLTVKPKWIHVDNTAAILFDKDVASDIVRFGIGLYGLNPSSAPGSRDLEPAFALKPAMSFVSELTYVKQIHKGYGVGYGSTHIAEEDEWIGTVPVGYADGWIRKFQGFKVKVGDTYCPIVGRVCMDQFMVLLPKEVPAGTPVELISADPAAPNSLRRAADWLDTIHYEVACQFNDRLDRIYDNE
>NZ_LT899687.1|WP_003620772.1|295636_296050_+|holo-ACP-synthase
MIKNIGVDQIEVDRIAKVVDRGDGFARKVLTDREFAQYQDLTHKRKIEYLGGRFAIKEAFSKAWGTGIGQAVSFEDVETLRTESGAPVTTSRIFTGRIFSSIAHDDHEIVAVVVLEEPAGWRRAIGKLSHLLSGRKK
>NZ_LT899687.1|WP_003622430.1|294100_295552_+|DEAD/DEAH-box-helicase
MKFTELGLNDNILKAIKRSGFEEATPIQAQTIPLALAGQDVIGQAQTGTGKTAAFGLPILQKLDLDKQEQAIQAIVIEPTRELAIQTQEELFRLGRDEKAKVQVVYGGADIGRQIRDLKKVPEILVGTPGRLLDHLKRKTIKLDGVKTVVLDEADEMLDMGFIQDIESILTYAENRDQTLLFSATMPKPIQALGEKFMHDPQVVKIQAKQLTADLIDQYFVRVRENEKFDTMCRLIDVENPDLAVVFGRTKRRVDELTRGLVARGYNAAGIHGDLTQARRMQVLKRFKEGELDILVATDVAARGLDISGVTHVYNYDIPQDPDSYVHRIGRTGRAGKSGMSVTFVTPNEIGYMRTIEDLTKKKMSPLRPPTDAQAFAGQMKQAVLKVDDLLSGDLSKYDDAAEKLLENYSAEDIAAALLKELSNDSEVKVTITPENPHPYRGKHSGGRGRGSRSRSGNKNFKGKRNFDRKKRKPGFKIHGRKG
>NZ_LT899687.1|WP_003620768.1|292723_294091_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MKMQLAEIAQALNTSCEGDAETVITSVAFDSRKISQGALFIPIKGERDGHDFVGSAIEAGASATLWEAGNPNKPEGIAVLEVADTLKAMQDLARYYLQKVNPTVVSITGSNGKTTTKDMVAAVLAKRFNVYKTQANFNNEIGVPMTILEMKPITEILVLEMGMDRAGQLHELSQLARPDVAVITMIGEAHIEFFGSRDKIADAKMEITDFLQEDGEFIYNGDEPLLAERAAKLPQDKSTFGFADSDSIHASDLRSTMHHSFFKINGTDREFSIPMIGRHNVANAMAAILVGRHFGESDEEIAAGLANFVPTANRMEWEKGDCGEDIMSDIYNSNPTAVKAVTASFGQVPVSEDGRRIAVLADMLELGSRSADLHKGLAACLDPDKINVLYLYGPEMNHLYQALLDKYGQQNLHYYPEDEMSHLIDDLKSDIHSQDIVLLKGSHGMHLERVLDRLK
>NZ_LT899687.1|WP_003620766.1|292364_292616_+|type-B-50S-ribosomal-protein-L31
MKKGIHPDYQEVCFMDAATGFKFVAGSTLKSSETVEFEGNTYPLIRVEISSDSHPFYTGKQKFAAADGRIERFNKKYGFNKKN
>NZ_LT899687.1|WP_003620764.1|290993_292265_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MKKMIIHGGKPLQGDIWIGGAKNSTVALIPASILSRTPVTLESVPRIADVDNLMDLLSEMDVHCDFRETTLQIDPTEIKMSPLPAGKIKSLRASYYFMGALLGRFGKAVVGFPGGDDIGPRPIDQHIMGFQSLGADVRCENEQIVITAPDEGLKGAKIHLKMASVGATMNIIMASVTASGRTVIENAAKEPEIIDLATFLNNMGAKIRGAGTDTIRIDGVDRLEAKVPHTIIPDRIEAGTYISMAACIGNGIRIHNIIAEHLDAFLAKVEEMGVVIDTDEDSLFVYPAGDLRMVQVKTGTYPGFATDLQQPITPLLLTAKTGEGVIIDPIYPKRTRHVPELQKMGAPITVVNNIILVQPGSRLHGAVVHADEIRAGACLMLTGLMVDGETVINNAGNILRGYDRVEEKLRQLGADVVIRDVED
>NZ_LT899687.1|WP_089119719.1|289254_290874_+|CTP-synthase
MTKYIFVTGGVVSSLGKGITASSIGRLLKNRGLKVTMQKFDPYINIDPGTMNPYQHGEVFVTDDGTEADLDLGHYERLVDVRTSKYSNVTTGKIYQEVLQRERRGDYHGGTVQVIPHVTNMIKEKVMRAAQMTDTDVVISEIGGTVGDMESTPFMEAIRQMRREVGSENVMYVHVTFVPYLRAAKELKSKPTQQSVSMLRSIGIQPNMLVLRSEMPVPQEMKDKISTFTDVPVDYIVESLDAPSLFDVPLSYQEQGVDQKVVDFLHIDSPKPVADMDEWRRMDERAKNLKYKTKITLVGKYFELEDAYISVTDALQHAGYLYNSKIEVEKIQAEDITEDNVAELLKDTQGLIVPGGFGTRGLDGMITSIKYAREHDIPFLGICLGMQMASVEFARNVLHLEDANSAEAEPNCKNNIIDLMADQRDQEKIGGTLRLGLYPAMLKAGTKTRECYDGQEVIQERHRHRYEFNNKYREDFEKAGMTFSGVSPDNHLVEIVEITDKKFFVAAQYHPEFLSRPNRPEGLFKGFIGAASGLQVDKF
>NZ_LT899687.1|WP_003620758.1|288568_289138_+|DNA-directed-RNA-polymerase-subunit-delta
MGLADFKDVDRNELSMIEVAHAILEDRGERMAFADIVNEVQKYLNKSDEEIRQRLPQFYTDMNTDGRFISMGENVWALRTWFKFEAVDEEVDHPEDDGDEESTRKHHKKVNAFLATTEGDDVIDYENDDPEDEDLSDDSDADEDDADDNSGDDYDDNEDDDDDDSLLDGIEDQLSQMDDDDLDDDEDEE
>NZ_LT899687.1|WP_002878700.1|288124_288523_+|DUF1934-domain-containing-protein
MSKIKIDLTSKITQGEQTETIRQQAEGELREDGAVKRIFYEAEKVPVKMLVKEQELLIRRGTDHSNFSQMHFILGEKGQCKYVVEGRQLDLLSETKRLELKENAAGQQLEVEYDLFSGVDLIGSYAVSLIFA
>NZ_LT899687.1|WP_003612856.1|298152_298710_+|aminoacyl-tRNA-hydrolase
MKLIVALGNPGLKYEKTKHNTGFMALDHYLDEKGLRLDRDKFTALYAKEKVAGEDVIFMEPQTYMNESGRAVGAAAKFFKIDPSDILVIHDDMDMPIAKLRIRAGGKSGGHNGIKSIIACLGTEKFNRLKIGIRHPDKQSVVSWVLTPFNPDQQKELEASFAKVDQIIDDFIAGKDAQYLMNRYN
>NZ_LT899687.1|WP_089119720.1|298726_302203_+|transcription-repair-coupling-factor
MQVIDFLKKDQGVTAFIAKTSRIKNSLLTGVERGAFAVLIQAYLAQVGQPLLLIEENEYKAQERYNDLSRLLADDDLELFALDGNLATQTAVSSPDELSSRIQCLNLLLSGRPGVVIATPQGLQYPLSAPALFKKGQKHFAVGDEIALPDLAQWLNQAGYHRENLVVKPGEFAMRGDIVDLYPLDRESPLRLEFFGDEIDTIKTFDLTSQRSLEELPEATVPAASDHVFTAEDLDRAGRELAGDLPKEAAASLEIAQEALANGQLPDDCNRYLDYLLPKSFSLLDYLPAKGLLLFNDWQLIAESVKNMGAINDDYLASQIASKMMTSRQKLRLDFDAVLKADCHHRLYVSLMAHSMGRLRFGQHLAWDSREPQQFFSQMELLKTELDSYAKKGQTVVLQVSSRRQAEEFNRSCHDYDIYLPLAEADGLKEGRVQLVIGGYASGFVLPDSDLVYLTEKELFNQNKRSKKRIKTLENAQRLRSYTELKPGDYVVHVNHGIGRFEGIQTLETDGKKRDYITITYQKGDQLFVPADQLSLVQKYVASEGKQPHVNKLGGSEWAKTKKRVAARVEDIADDLIELYAKREAEKGFAFSPDGSDQAAFEAAFPYEPTPDQLRATAEIKADMEKAKPMDRLLVGDVGFGKTEVAMRAAFKAICDGKQVAFLVPTTILAQQHYQTIKDRFKGFPVEIASFSRFQGQAESKKIVAGLKDGSIDLVVGTHRILSKDVQFKDLGLLIIDEEQRFGVAHKEKLKQLKTNIDVLTLTATPIPRTLHMSMIGIRDLSVMETPPQNRYPIQTYVLEQLPGTVKEVCQREMQRGGQVFYLHNRVGDIEETVARLEQLLPEARIAYAHGQMSENQLEDILSRFLDREFDILVTTTIIETGIDMPNVNTMIIEDADHYGLSQLYQLRGRIGRSARLAYAYFLYQPNKVLTEVGEKRLDAIRDFTELGAGFKIAMRDLSIRGAGNMLGAQQHGFIDSVGYDLYSQMLADAIKERQGKKPVKKSNAEVDLGLEAYIPEDYIADQEQKIEFYKKIKGIGSLQNREDIEDELLDRFGDYPAAVENLLNVASLKASCDLAQILTLVKEKAQIRVIFSDSGSREMEGPNIFKALEHVSWKARIALGAQNRLVVTLLLPDKLTRRAMFTELGTFAKDAAEIIQR
>NZ_LT899687.1|WP_002878680.1|302271_302514_+|RNA-binding-S4-domain-containing-protein
MRIDKFLKISRLVKRRTVAKEMADQGRVSVNGKTVKSSYNVVVGDVIAVAYGTRVIKARVLDLRETTKKAEAGDLYELVD
>NZ_LT899687.1|WP_003612818.1|302579_302960_+|septum-formation-initiator-family-protein
MGNNRGNQQNVTPLRPDQDVRRLKKRQIKFREVHRVRRNRLLALILLVFAVLGFQLAMTKARTAKIQKQVSQNQATLTKIKKNKEKLTNERDDMKDSDYVAKVIRYKYKYTKDGERVYNIKEKGDN
>NZ_LT899687.1|WP_011678015.1|302959_303313_+|S1-RNA-binding-domain-containing-protein
MNYKVGQRLDGVINNVTDLGIFVTLPKHKSGLVHRNDFGSDWPRKRQHWQVGDQVRVVVQNLRKGRLDLSIRRVNDPDLIDPTNQFSQLRAGDFARVLNQVDQEARAEIEQLEAALK
>NZ_LT899687.1|WP_089119721.1|303359_304655_+|tRNA-lysidine(34)-synthetase-TilS
MDIKKRLSAFFAEEGLPLEGNFLVAASGGPDSMALLDLMRRLPGGFQLYAAHLDHQLRADSQKESQVLRAYCHKYQLPLYESVWPKSLHPESGLEAAARDYRYNFLFEVARQVKADYLLTAHHGDDLLENILLKLVRSGIPREMNSLKPVSQRGQVKLVRPLLVVGKADLLAYAKKQGLEYVEDETNFTGITARNRLRQEVVPLLKKESPDLLENAWRFSQEMTAEEDYFAQAAGKLPEPEPFFGGWRIPKAAGQAESELVKAYLENFIQKKYNKRVQLDRILLANRQSQEKGGLHLSFYQGHYWLYPVKQPAPSPLEEVVAGQPFFFRGNCYLLSEEKREESPLAEISFPGKLSAGSLPNGQRLLLKDGRRTKSKKLFAAAGIPLALRGNCLSLFAGQEAVYVAGCYQQAVKEGKRPLYLYQVKTCKKGR
>NZ_LT899687.1|WP_089119722.1|304725_306939_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MKNNRNRLFSNGLFYIVVFLLLLWGINWVLGGSSNSGATETISYSEFVKKLRNGEIKDFNVQPSNGVYSVTGSYKSSQTKSSSSSDIFGGNTSSKVTGFSTTMLENDSSVKKVQDLAQSENVKMSTQGESQSSNWISTIIMLVPTVLFIVLMVMMMNQGGSRGQGGGIMNFGRSNVKPQDPKKNKVRFDDVAGEEEEKQELVEVVEFLKNPARYTKLGARIPSGVLLEGPPGTGKTLLAKAVAGEAGVPFFYISGSDFVEMFVGVGASRVRDLFTNAKKNAPSIIFIDEIDAIGRKRGNGQGGSNDEREQTLNQMLVEMDGFEGDEGVIVMAATNRSDVLDPALTRPGRFDRKVLVGPPDVKGREAILRVHAKNKPLADDVDLKEVARQTPGFVGADLENVLNEAALVAARRNGTKITAADIDEAEDRVIAGPAKKDRMISKKERERVAFHEAGHSICGLVLSDSRTVRKVTIVPRGRAGGYNIMLPKDDQFILTKKQLFEQIVGLMGGRAGEEVVVGDQSTGASNDFEQATTIARSMVVNYGMTDELGMVELEKEGEGTPYGFKPYSEATAAKIDEAVKKILDEAHAKAVEIVENNREKHRIIAEALLKYETLDEKQIYSLYKTGKMPEKSSEEFPSEAKALSYEEAKEVAQKRAEEKAEEDTAEKQALATPSEDAVKPETDAAKLAEPDASASQEDPADSLPTPSESDLSKDPEKDDNDAPSQKTEQTDDSDKDE
>NZ_LT899687.1|WP_003622441.1|306983_307865_+|Hsp33-family-molecular-chaperone-HslO
MNDYLIKAINASKDLRLLTINGKDLVAEAQKRHDTWSASSAVLGRSLLGTLLLAGAELKGDQELTLRLLGDGPVGAAVVTAKSDLTVKGYVQNNHVALPAREDGHIDVKKAVGKGWLQVTKDLGLKQPYTGEVPIVSGEIAEDLTYYLAKSEQIPSAVGLSVFVNPNDTIGAAGGFLLQALPGASEELLQETEDRIKALPQLSSAFLDGMTPEDLAKKILGDDCKILEKDEVSYHCDCSKEKYAGMLETLKGSQLKEMIDEDHGAELVCNFCGNKYNFTEAELQAILDKKLGK
>NZ_LT899687.1|WP_089119723.1|308325_309936_+|peptide-ABC-transporter-substrate-binding-protein
MTAAGLLTASALVLAACGQQKSSQSQTKQVLNWIESAQISTQDPSLTTDSTSFQALLNTQEGLYRLDKKQKPQLALAKSAKVTDGGKTYTFVLQDAKWSNGQAITANDFVYSYRRSLNPKTKSSMAFYLYQIVNAEAINAGKKPVSSLGVKALSKNKLQIKLVRPVSYFKLLLAFPLFFPENQQFIEKVGSKYGTAAKYTISSGPFKLTKWTGSNKQFTLVKNQNYWDKKNVKLDKVNETISETSSTAYNLYQAGKLDETYLTGEQVKANKGKSTFYDQPASAIQRLELNRKKVKAFNNFNIRRALSLAIDRESLAKVLSDGSVAAKGFVPSGMGNNPTTGEAFYKEAYVKEAVSYNLKEAKKYLAKGYKELGIKSLNLNLTVSDTDSAKQVGEFLQSKLGELPGVKITVTILPYTTLISRQSAGNYQLTIKNWQAILGDPINFLDVFEKDSSYNTSGFASSKYDQLLNEAENVYGNKPVQRWKRLVAAEKLLMNEQGTIPLIQTAKPQLVQSYVKNVSYNPLGIPYDFKLVYIKK
>NZ_LT899687.1|WP_089119724.1|309945_311232_+|peptidase-T
MAFSDFDFLEKNFIHYAKEDTQSKYANKDQVPTTPNQVKMMKELADQVKDYDLESYYNEKTAFAIGHLAANTAGVAPIGFFAHVDTVEFDDRFPIRPQVHRDYQGQKLALDEANGIFLDPEEFPDLLNLKGQTLITSDGKTVLGTDDKAGVAGLLAALKYLHEHQEVEHGDIYVAFGPDEEIGLGGQRFDPADFPGVEFAYTLDNGRPGDFEYETFNASAADLTIKGTVVHPGEAYGLLVNATTIMTEFLAALPQDQVPEKSRGHEGFIMVTDAQSSVDSAHVGLIIRDFDWDEFLAKEDLVKKLVASLGEKYGPDRFQLDLRRQYENIYNGVKDRPYVVNLALDSYEKAGLAPNVQTFRGGTDGNFITKKGIPTPNLFNGGGNYHGRYEYVTVEQMDKLAEVLVTIADEHARQSKEGQDKRPLEKYW

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Crispr_ID: NZ_LT899687_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT899687_2

751606-752367

TypeII

Consensus_repeat	Method
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	PILER-CR
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CRISPRCasFinder
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CRT

11 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_LT899687_2

>merge|NZ_LT899687|2|751606-752367|PILER-CR,CRISPRCasFinder,CRT
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCATCCGGCAGAACTAGTTGTTCCGCCGGGAGGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCTATTAACACCGACACCGACGGCCCAAACCCGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCCCTCTGCTTGTTTAAGCTTGCTTATCGTTGGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCGGCGCCAGCAGAGCGTTATCGCGTTGCTCAGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCATTGCTTGGTTAAGCTAGCAGTTGCGTTATGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCCAATTAACTTTATTTCCTTTACGCTTTATAGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCCCATAGTTAAAATCTCCTCTTTAAATTAAGGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCGCAAGGCGGCCGACTCACTAGCCAGTGCTGGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCCAGCCCAGGCACGGGCTCTCTTGGCTTCTGGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCCATTGTTACCACGCTTTCTATAAATCCTTCGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCCGATCTTGTCAGAGTGGTTGAGCATGTCGTCGTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCG

>NZ_LT899687|2|1|751606-752367|PILER-CR
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATCCGGCAGAACTAGTTGTTCCGCCGGGAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	TATTAACACCGACACCGACGGCCCAAACCC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCTCTGCTTGTTTAAGCTTGCTTATCGTTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GGCGCCAGCAGAGCGTTATCGCGTTGCTCA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATTGCTTGGTTAAGCTAGCAGTTGCGTTAT
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAATTAACTTTATTTCCTTTACGCTTTATA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCATAGTTAAAATCTCCTCTTTAAATTAAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GCAAGGCGGCCGACTCACTAGCCAGTGCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAGCCCAGGCACGGGCTCTCTTGGCTTCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CATTGTTACCACGCTTTCTATAAATCCTTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GATCTTGTCAGAGTGGTTGAGCATGTCGTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCG

>NZ_LT899687|2|2|751606-752367|CRISPRCasFinder
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATCCGGCAGAACTAGTTGTTCCGCCGGGAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	TATTAACACCGACACCGACGGCCCAAACCC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCTCTGCTTGTTTAAGCTTGCTTATCGTTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GGCGCCAGCAGAGCGTTATCGCGTTGCTCA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATTGCTTGGTTAAGCTAGCAGTTGCGTTAT
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAATTAACTTTATTTCCTTTACGCTTTATA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCATAGTTAAAATCTCCTCTTTAAATTAAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GCAAGGCGGCCGACTCACTAGCCAGTGCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAGCCCAGGCACGGGCTCTCTTGGCTTCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CATTGTTACCACGCTTTCTATAAATCCTTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GATCTTGTCAGAGTGGTTGAGCATGTCGTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCG

>NZ_LT899687|2|1|751606-752367|CRT
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATCCGGCAGAACTAGTTGTTCCGCCGGGAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	TATTAACACCGACACCGACGGCCCAAACCC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCTCTGCTTGTTTAAGCTTGCTTATCGTTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GGCGCCAGCAGAGCGTTATCGCGTTGCTCA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	ATTGCTTGGTTAAGCTAGCAGTTGCGTTAT
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAATTAACTTTATTTCCTTTACGCTTTATA
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CCATAGTTAAAATCTCCTCTTTAAATTAAG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GCAAGGCGGCCGACTCACTAGCCAGTGCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CAGCCCAGGCACGGGCTCTCTTGGCTTCTG
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	CATTGTTACCACGCTTTCTATAAATCCTTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCC	GATCTTGTCAGAGTGGTTGAGCATGTCGTC
GTTTTAGAAGGTTGTCTATTCAATAAGGTTTAACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT899687.1\|WP_003619905.1\|761761_762199_+\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_LT899687.1\|WP_089119826.1\|752723_753824_+\|thiolase-family-protein	unknown	unknown	gnl\|CDD\|238383
NZ_LT899687.1\|WP_089119827.1\|753825_755052_+\|hydroxymethylglutaryl-CoA-reductase,-degradative	unknown	unknown	gnl\|CDD\|153082
NZ_LT899687.1\|WP_089119821.1\|743110_743779_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LT899687.1\|WP_089119828.1\|759471_761733_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_LT899687.1\|WP_011543826.1\|742499_743114_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|225232
NZ_LT899687.1\|WP_089119818.1\|740632_740836_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT899687.1\|WP_089119823.1\|745212_749496_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	mkCas0193_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|374653
NZ_LT899687.1\|WP_089119824.1\|749714_750626_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_LT899687.1\|WP_014564826.1\|756383_757742_+\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697
NZ_LT899687.1\|WP_035162685.1\|750603_750909_+\|CRISPR-associated-endonuclease-Cas2	cas2	mkCas0206_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|226043
NZ_LT899687.1\|WP_089119825.1\|750905_751574_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd12218_csn2_CAS-II-A	gnl\|CDD\|213411
NZ_LT899687.1\|WP_003619907.1\|762481_763768_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|273080
NZ_LT899687.1\|WP_089119829.1\|763783_765628_+\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_LT899687.1\|WP_089119822.1\|743781_745041_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_LT899687.1\|WP_003619897.1\|757799_758306_-\|aminoacyl-tRNA-deacylase	unknown	unknown	gnl\|CDD\|237976
NZ_LT899687.1\|WP_014564825.1\|755055_756219_+\|hydroxymethylglutaryl-CoA-synthase	unknown	unknown	gnl\|CDD\|213655
NZ_LT899687.1\|WP_089119819.1\|741175_741400_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_LT899687.1\|WP_089119820.1\|741852_742299_+\|FMN-binding-protein	unknown	unknown	gnl\|CDD\|226484
NZ_LT899687.1\|WP_003619900.1\|758386_759331_+\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|234786

Protein	Function_ID	Function_description	E-value
NZ_LT899687.1\|WP_003619905.1\|761761_762199_+\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	3.03729e-86
NZ_LT899687.1\|WP_089119826.1\|752723_753824_+\|thiolase-family-protein	gnl\|CDD\|238383	cd00751, thiolase, Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.	2.68959e-161
NZ_LT899687.1\|WP_089119827.1\|753825_755052_+\|hydroxymethylglutaryl-CoA-reductase,-degradative	gnl\|CDD\|153082	cd00644, HMG-CoA_reductase_classII, Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class II, prokaryotic enzyme is a homodimer. Class II enzymes are found primarily in prokaryotes and Archaeoglobus fulgidus and are soluble as they lack the membrane region. Enzymes catalyze the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. Bacteria, such as Pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. Human and bacterial HMGR differ in their active site architecture.	0
NZ_LT899687.1\|WP_089119821.1\|743110_743779_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.34412e-66
NZ_LT899687.1\|WP_089119828.1\|759471_761733_+\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_LT899687.1\|WP_011543826.1\|742499_743114_+\|GTP-pyrophosphokinase	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.12268e-62
NZ_LT899687.1\|WP_089119823.1\|745212_749496_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|374653	pfam16592, Cas9_REC, REC lobe of CRISPR-associated endonuclease Cas9. The REC lobe of Cas9 - the CRISPR-associated endonuclease Cas9 - includes the REC1 and REC2 domains. REC1 forms an elongated, alpha-helical structure consisting of 25 alpha helices and two beta-sheets, whereas REC2 inserted within REC1 adopts a six-helix bundle structure. The REC lobe and the NUC lobe of Cas9 fold to present a positively charged groove at their interface which accommodates the negatively charged sgRNA:target DNA heteroduplex. CRISPR (clustered regularly interspaced short palindromic repeat)-Cas system occurs naturally in bacteria as a defense against invasion by phages or other mobile genetic elements. Cas9 is targeted to specific genomic locations by sgRNAs or single guide RNAs, in order to complex with invading DNA in order to cleave it and render it inactive.	1.28047e-124
NZ_LT899687.1\|WP_089119824.1\|749714_750626_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.28656e-95
NZ_LT899687.1\|WP_014564826.1\|756383_757742_+\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	7.30016e-63
NZ_LT899687.1\|WP_035162685.1\|750603_750909_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	3.0201e-28
NZ_LT899687.1\|WP_089119825.1\|750905_751574_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213411	cd12218, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.40977e-69
NZ_LT899687.1\|WP_003619907.1\|762481_763768_+\|histidine--tRNA-ligase	gnl\|CDD\|273080	TIGR00442, hisS, histidyl-tRNA synthetase. This model finds a histidyl-tRNA synthetase in every completed genome. Apparent second copies from Bacillus subtilis, Synechocystis sp., and Aquifex aeolicus are slightly shorter, more closely related to each other than to other hisS proteins, and actually serve as regulatory subunits for an enzyme of histidine biosynthesis. They were excluded from the seed alignment and score much lower than do single copy histidyl-tRNA synthetases of other genomes not included in the seed alignment. These putative second copies of HisS score below the trusted cutoff. The regulatory protein kinase GCN2 of Saccharomyces cerevisiae (YDR283c), and related proteins from other species designated eIF-2 alpha kinase, have a domain closely related to histidyl-tRNA synthetase that may serve to detect and respond to uncharged tRNA(his), an indicator of amino acid starvation; these regulatory proteins are not orthologous and so score below the noise cutoff. [Protein synthesis, tRNA aminoacylation].	0
NZ_LT899687.1\|WP_089119829.1\|763783_765628_+\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_LT899687.1\|WP_089119822.1\|743781_745041_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.27516e-28
NZ_LT899687.1\|WP_003619897.1\|757799_758306_-\|aminoacyl-tRNA-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	1.02683e-65
NZ_LT899687.1\|WP_014564825.1\|755055_756219_+\|hydroxymethylglutaryl-CoA-synthase	gnl\|CDD\|213655	TIGR01835, 3-hydroxy-3-methylglutaryl_CoA_synthase, 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade. This clade of hydroxymethylglutaryl-CoA (HMG-CoA) synthases is found in a limited spectrum of mostly gram-positive bacteria which make isopentenyl pyrophosphate (IPP) via the mevalonate pathway. This pathway is found primarily in eukaryotes and archaea, but the bacterial homologs are distinct, having aparrently diverged after being laterally transferred from an early eukaryote. HMG-CoA synthase is the first step in the pathway and joins acetyl-CoA with acetoacetyl-CoA with the release of one molecule of CoA. The Borellia sequence may have resulted from a separate lateral transfer event.	1.04956e-130
NZ_LT899687.1\|WP_089119819.1\|741175_741400_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00102541
NZ_LT899687.1\|WP_089119820.1\|741852_742299_+\|FMN-binding-protein	gnl\|CDD\|226484	COG3976, COG3976, Uncharacterized protein conserved in bacteria [Function unknown].	1.45884e-11
NZ_LT899687.1\|WP_003619900.1\|758386_759331_+\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|234786	PRK00517, prmA, 50S ribosomal protein L11 methyltransferase.	1.78716e-91

>NZ_LT899687.1|WP_089119825.1|750905_751574_+|type-II-A-CRISPR-associated-protein-Csn2
MIITYKAHKSFEIENGKVNVIATSSPIAYCNLIEGMQEKNELLCAVSEDYDAIPLSKAVDWLGDPLISESLLQKYMTKLTSYVVDELSADGRNRIITFYRDLLNAVQDELLMEDLPLEISFDTDLKKLFKFGGLHFNKTLTHDPYGIIETVLRIHDRLDLKSTVVFSNVAHYLAVEQFNEISKLCLELKKSIIFIEFCSHKDQVVYGDAKFSYIDEDLVDWY
>NZ_LT899687.1|WP_035162685.1|750603_750909_+|CRISPR-associated-endonuclease-Cas2
MRLMIMFDLPVDTAVDRKQYRQFRKNLINEGFVMIQYSVYVRVCASKKAAELLEKRIRGYVPEYGVIQSLMLTEKQYNDMHFLLGEPVKDIRNTSDRTVIL
>NZ_LT899687.1|WP_089119824.1|749714_750626_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRNVIITQHSKLSYSSNMMVVHTKDGVSQIPVSDINMLVVLTTQAVITSALIAELAKKQTKVIFVDEKQEPICETENYYSTNCHPEKLIKQFNWDEDRKQILWTKIVAAKIQNQMNVLRIYGLPTDKIEKDFLELELNDASNREATTARKYFTELFGKDFKRREGSNALNAALNYGYSILLSAVNRKITMDGNRTYMGVHHSSEHNPFNLGSDLMEPFRPFVDYWLYDHKNIKEFTPDIKYGLVELLSLRIIYNGDRMILGNAINQYVHDCLRYLDGNLFEMDIELGVDYEVPNDAIDDNV
>NZ_LT899687.1|WP_089119823.1|745212_749496_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MAKPKDYTIGLDIGTNSVGWVVTDDQNNILRIKGKKAIGARLFTEGKVAAERRSFRTTRRRLSRRRWRIKMLEELFDEEIAKVDPSFFARLHESWISPKDKRKRYSAIVFPSPEEDKKFHESYPTIYHLRDKLMKDDQKHDIREIYIAVHQMIKARGNFLHDESVETYRSGMSSLGGRSERTILSVQTLEELNDLFAENEGTEEVELNVASAEQINDILTGGHLNADSQKEISNLLLPSSFPSFDDKAKEKQVKKLINDVATNISKAWLGYKADFSTILNLAKIDKDQKKIFAFALQGGDEEDKVQELESLLEQSQTDIVDRLIEIRHAIVLSEIVPVGMTLSEAMIDKYDQHKEDLITLKAVIRNTKDKKKAAKLQAIYDLYVKNRHADLAKAMKLTGIKKRSELLDPEELKKGISSLLDDSPEAVEIKQRLEEKTFLPLQRSNNNGVIPNQLHQVELDEIIKKQSKYYPFLAEKNPDESEEAQKKAPTKLDALLTFRVPYYVGPMITKEEQEAQNGHSFAWMVRRDPQDHEAITPWNFEKKVDKMASATQFIKRMTTKDTYLLGEDVLPASSLKYQLFTVLNELNNLRVNGKKLTSDEKEQVIEGLFKKQKTVKADKFVKYWQAKHIGADIKVKGLSDPSKFNSTMSTYIDFKKIFGDQLNDVNRQNDFEKIIEYSTIFEDRKILEDKLRADFAWLSEEQIKQLCRLRLQGWGRLSDKLLTRLTDADGQNVLERLWNSNDNFVQIVSDPNIKAKIEQENQKLLRDSQSDNAVESILDDAYTSPQNKKAIRQVMRVVHDIVKACDGNVPAKFAIEFARSQEDDPKRTTARINQMQKIYDQISDEVVSQGVKEQLSGMKSLKDRYYLYFMQGGRDAYTGAKLNIDRLSDYDVDHIMPQSFVKDDSLDNRVLVARAVNNQKSDKVPALLFGNKVVADLGITVREMWDKWQKLGMISKRKLSNLLTDPDALTEYRAQGFIRRQLVETSQVIKLTATILQSEFPDSKIIEVPAKYNSIVRKQFDLYKSREVNDFHHAIDAYLSTIVGNYLYQVYPNLRRMFVYGEFKKFSSNAEESAHDVARRVKSMNFLDDLLRGTHGDNIYCRSTGEIVFNRNDIISKLKQAYSFKQMLVTQEVFTRKSALFDQTVYPSPERDSKKRSGLIPRKKGMDTEIYGGYSGNKDAYFVLAEAVKEKGHTLQIVGVPIRALNTLKNSANYSEKLLEIIKPQVMFNKKNGKPIKGIKDVKILMDKIPCRQPVLEGESYYMLASSKYRYSLKQISLSQMSMKYILDYIDDPNFNKHEMINIDQQDEKECLLSVYDEILEKMDKYLPLFDIRSFRKKLHDGRDAFIALPVASEEKKPGEVDVIRKILKGLHANADITNLAELGFGTAALGALVSTGGIKISDDAVFIYQSPTGLFERRVKVSDLLK
>NZ_LT899687.1|WP_089119822.1|743781_745041_+|HAMP-domain-containing-histidine-kinase
MIKKIRRRFIWLATLSLFLVMFFSFSSLIGISLFESSHEADQVLSIIVKNNGRLDEVQAKKRLGDQYNKEGMFKYRYFTANINTKKQTLTVIDADHIIGYSINSVSSRKKQISRRLSASQLKGTIHSNGVRFRYLAKKISANKYYICFIDLSPLMQSALLLVRYALIFTFGGILFFVIIMTLLADKAIQPIKDAYYKQRRFITNAGHELKTPLAVISANAEMEELLGNDDEWSESTKEQVVRMTGLINQLITLTRMSEPEELVLSKVNFSEITKESADSFKSVLAKDNKKYVVSIDPDLYINAEQRSLLELVNILIDNAQKYCDPEGEVMVVLAKSRLNQNAVLTVTNSYKNGAGIDTNRFFERFYREDESHHYDQKQKNGFGIGLSMAQDLVAAFGGKINASWSDGVMNFTVTFKRVH
>NZ_LT899687.1|WP_089119821.1|743110_743779_+|response-regulator-transcription-factor
MKILLAEDEAQLNRVLTVAMQKSGYDVDSVFNGQEAVDAVKKHPYDVIIMDIMMPVKNGLDAVKEIRSTGDKTYIMMLTAKSEIDDKVTGLDVGADDYLTKPFSLKELLARLRSKERRSEDYNSTQELNYDNLKLDLNSQELSSNNSIGLSKQETGLMRYFLLNPGKAISTEELFNHVWKNEDESEDVVWVYISFLRSKLASIGANVQISGEKGGEFCLERT
>NZ_LT899687.1|WP_011543826.1|742499_743114_+|GTP-pyrophosphokinase
MSIYGKYADYLPQILDSVLQQIQGIGQEYSAEHGQKLYGHLEGRVKGEESMAQKCERKGLPLMPESALIENRDAIGLRIVCNFIDDIYTCIDLLKKQDNFKIINEKDYITDAKPNGYRSYHLIMEVVTPFEDVHGNKPGIYYVEIQLRTIAMDTWASLEHEMKYKHDIKNPERISKELKRVADELASCDVSMQTIRQLIKEGEL
>NZ_LT899687.1|WP_089119820.1|741852_742299_+|FMN-binding-protein
MYKKGDYEVEAEGHHSTVKLRVSFDEEKLTKIEVLEENETQAFVDDLKDRFIPEVVANQSLNVDAISGATKLAKAVTSSVEEAITEAGGDPKTFIEAAHVAKDDQVIPGMYVVGTDYSPYYDIPGFCYGSCIGSGVIAGHEASAYAKA
>NZ_LT899687.1|WP_089119819.1|741175_741400_-|helix-turn-helix-transcriptional-regulator
MNALQEYLDQNGVTRYQVAKQTGIANTTLANAVKETKPLSGQTVKVISAVAQTLGKTPSQVLDDLIELDEDNSK
>NZ_LT899687.1|WP_089119818.1|740632_740836_+|hypothetical-protein
MGESKEDKRMRAKWESLSGAEKLEFKKNYAMRRGITIDFIRRWAWNEGDLDNLEYHIAERRKKFREF
>NZ_LT899687.1|WP_089119826.1|752723_753824_+|thiolase-family-protein
MKDIYIVAAKRTPFGRYHKQLADFSAIDLGQIALRGALKEAGLDAEDLDALFMGNVLSAGLGQNMARQIALNAGMRQDSVAVSINEVCGSSLKAARLAEAQMLIGDLGLVAVGGSESMTNASKEIMFSDGLVDSFSGKSMGITAENVAKRNHISRQDADAFSLSSHQKAVKAQAEGLFADEIIQIEDLKQDENVRPDTSLEALAGLKTSFLEDGTVTAGNASPISDGASMIILATAEKVTEYQLTPLAKLGAYAEVGYDPEFMGYGPYYAIRKLLNETGRQVADYDFFEINEAFAATTLAVARDLEIPLAKVNKQGGAIALGHPLGASGTRLMATAARQLQRGGQRAIASLCIGGGLAIAFEIEKA
>NZ_LT899687.1|WP_089119827.1|753825_755052_+|hydroxymethylglutaryl-CoA-reductase,-degradative
MKFYQLPPEERRQFLQEDGVALEDIPAADLARLDEMSENVVGEVKFPLSCLTSALVNGKNWRIPMTTEEASVVAAANHGMSVFAKAGGVKATSQRDGIYGQIVLEVTEAFSLAGFKKEFPAYIKEANKEFASLIRHGGGLKDLTARQEADLVYLLALVDPAEAMGANKTNAILEFLAQKMLAFPGVEAKLFAILSNYPSQLTTAKVAIPVSLLSKKGDLAEGREVAKKMALLAKIGSSDPYRAVTNNKGIMNGVDAVMLATGNDYRAVEAACHAYAAKSGQYRSLSSWKIAGEKLLGQVTLPLALGVVGGSISSRPDIRQSYAILGKIKAAELAELTASVALANNFAALSAISTKGIQAGHMRLQSRNVVQTLPASAEEKAAVYQMMISQGKYGETAAKNFLKELRGQ
>NZ_LT899687.1|WP_014564825.1|755055_756219_+|hydroxymethylglutaryl-CoA-synthase
MDIGIDQIGFYTPNKFVDMVDLANARNQDPNKFLIGIGQDRMAVADKTQDAVSMGINATAEYLDQVDLEQLGLLIFATESGIDQSKSASLFVKEALNLPARIRTFEIKEACFALTASLQVARDYVRAHPHHSAMIIGSDIARYGLATAGEVTQGAGAISMLIKENPAIIALEDGHTSHSENINDFWRPNNLATAVVDGHYSRDVYLDFFKSTFKPFLAEKQLQVSDFAGICYHLPYTKMGYKAHKIAIEGQDDETVKRLSDNFQLSAKYSRQVGNIYTASLYMSVLSLLENGDLEAGDRIGFFSYGSGAMAEFFSGKVVAGYQKRLRPALHARMLKERIRIGVGQYEDIFTEGLEALPENVEFTSDANHGTWYLAGQEGYVRQYKQK
>NZ_LT899687.1|WP_014564826.1|756383_757742_+|threonine/serine-exporter-family-protein
MKTESTEQEYQHHLSHHHHMRVQWEEFFQSDDETKIKEATLIEKGSIISRVGMMILSCGTGAWRVRDAMDTLARTLDLTCSTDIGLISIVCTYFDVDNQSYSQSLALPTTGVNMAKLNELEKFVRQFEAAGGDFEIKTVRRRLGEIEHMKGRYPLWGSSLAAALACGGFIFLLGGGVPEIICSFIGAGLGQFARGSLAKRRITVAATTAVGVAAACLSYYLAFMLGHLLFNVDMIHMRGYIGAMLFVIPGFPFITSGLDIAKLDMRSGLERMAYAILIILIATGTGCVMATALQIKPGDLPALHLSKAILTACRLLASFCGVFGFSLMFNSHRRMAAAAGLVGAIANTMRLSLVDFAHFPAPLAAFLAALLAGLLAGYVREKVGYPRIALTVPSIVIMVPGLYMYRGIFFLALTNVGAGATWMTEALMLVMSLPAGLLTARILNDKKWRRVD
>NZ_LT899687.1|WP_003619897.1|757799_758306_-|aminoacyl-tRNA-deacylase
MSKKKKNKDKLDKTLVEKILDQHKIAYEQHISEISEDHGVAQVGTGKPVLDGHPVYKTLAVNGNKTGPIVGVVPLSGHLDLKKIAKASGNKKCEMIPLKQLEKTTGYVHGANTPIGIYHSKKFPIFLDESVLKEDGIWVSSGEVGRSVMVNPLDLQKLVKATVADLQE
>NZ_LT899687.1|WP_003619900.1|758386_759331_+|50S-ribosomal-protein-L11-methyltransferase
MKLLEIKIESSYDVEDALAYFATEDLKALGTEARRRSDFEQAGWLHDSTVVDMDDIPNLPDELEFIAYFDEETDPEEMVKRFKDKLAELAGYGLKTAPGEISVDYVADQDWNTVWKKYYHVINLSRHLAIVPEWEDYQPAFKDQEIIRLDPGLAFGTGNHQTTQLAMLGIERAMVKPLTVADVGTGSGILAIAAHKLGAKSVLATDISDESMTAAEENAALNGIHDIALQKTSLLADVDGKFDLIVANILAEILLDLIPQLDSHLNEDGQVIFSGIDYLQLPKIEQALAENSFQIDLKMRAGRWIGLAISRKHD
>NZ_LT899687.1|WP_089119828.1|759471_761733_+|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MSKYTEMTHEQVMAACKKYITADQLAFVESAYQFAARAHEGQTRASGQPYIVHPIQVAGTLANLGLDPDTVAAGFLHDTVEDTSVTNDDIKEKFGADVAFIVDGVTKLNKYEYKSHKEFLAENHRKMLIAMAKDLRVILVKLADRLHNMHTLEHLRPDKQRRIAAETLDIYAPLADRLGIGTIKWKLEDMSFHYMNPEAYYKIVFMMDAKRSEREGYIKDAIDYLRGTLDSLGIKYDISGRPKHIYSIYKKMVNKHKNFNEIYDLLAVRVIVPTVKDCYAVLGAVHTKWKPMPGRFKDYIAMPKANGYQSLHTTIIGPGGKPLEIQIRTEEMHKVAEYGVAAHWAYKRGNFQGVDEKEGGALDIGREILELQKDSSDADEFMEAVHSDIFADKVYVFTPKGEVYELPKGSVTLDFAYAIHTQVGDHAIGAKVNDKLVPLDYKLKNGDVVDILTQSNARPSRDWAEMVKTSRAKNKIRRYFRDVDREESLARGKSELVDLLKENGLSAKDFLDKSHIDEVLDHFSFKTDEDMYAAIGFGNMSAVSIYNRLTADLRRQQEEEKQKQFEAQIMSAGQQAAASSVVKKPAPQKDDAKSKTKGKKPDSLVRVQGLEDLDMHFAKCCNPVPGDLIVGYVTKGRGVTVHRIDCRNVVSADPAAQGRMIDVEWNNIDEGKQASFNANFELFGYNRQKLLGDVINRLNALTKNITNVSASVNEENIAHFYITVEVRNAAQLNDIMAKLRDIPDVYDTKRTDN
>NZ_LT899687.1|WP_003619905.1|761761_762199_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRVVIQRVNHAAVRIDGETVGQIQKGLLLLVGLAEGDGEEQVVKAADKIAKMRIFEDEAGKTNLGIKDVGGQILSVSQFTLLADTKRGNRPSFVHAMRPPKSSQLWEEFNQELVKRGLTVETGEFGADMKVELENDGPFTIVLDL
>NZ_LT899687.1|WP_003619907.1|762481_763768_+|histidine--tRNA-ligase
MRVQRPKGTVDILPETSGQWEKVEQTARDLFKRANYHEIRTPSFENYELFSRSSGETSDVVEKEMYDFEDKGGRHIALRPEGTAGVVRAYVENKIYGPDYVKPFNVYYIAAMYRYERPQAGRQREFHQIGVESFGSNGYLADVETILLGHDLLAELGVKNYELHINTLGDSEVRQAYHDALVDYFTPVKDQLSEDSQRRLGKNPLRILDSKAEEDQQFLSEAPKIRDYLDEESKENFNKILASLDKLGVKYVIDDDLVRGLDYYTGVIFEFMVDDPTLWASPSTVLGGGRYNHLVEEFSGPETPAVGFGIGEERLMLVLSKQNPEMFEDQGIDFFITNIGEGTDIKAVEVARQLRSLGFSAQYDVDQKKLKAQFRKADRVGARYVVTLGAKELAEGKLTVKRLSDGQQFSLEFTDLEDKANLLSKIEK
>NZ_LT899687.1|WP_089119829.1|763783_765628_+|aspartate--tRNA-ligase
MMQMEKRTDYCGNITSQYLDQDVLLYGWVQRVRNLGQLIFIDLRDREGIVQVVVNHDSGQELMDVASSLGQEYVVEVKGHVNERSSKNPDMKTGDVEVIASEITVLNKAKTPPFEIKDDLVASEQTRLKYRYLDLRRPTLQNALIMRAQIMTATNAYLSGEGFINIETPDLGKSTPEGARDYLVPSRVYPGSFYALPQSPQIFKQLLMGAGFDKYYQIARCFRDEDLRGDRQPEFTQIDLETSFMDEEGVQEVTEGLLAKVMKDVKGIDLQLPLPRITWQESMDKYGCDKPDTRYEMLIHDLGNVFAKSGFKVFASALENGGFVRGIAVKGGAKFYSRKKIEAMQDYIKRYHAKGLAWVKYEDGDFSGPVSRFLSEEEKAGLVQEFSLEGGELLLFIADQWKVCCDSLDYLRRQTAKETGIIPKDTYKYLWVVDWPLFEYDEGDERWIAAHHPFTMPDAKGIELLETDPHKAHARSYDIVLNGYELGGGSIRIHKRDIQEKMFKALGFTKERAYEQFGFLMDALDMGFPPHAGLAIGLDRFAMLLAGKDNIRDVIAFPKNASASEPMMHAPAPVADQQLTDLGIEVAEAAKEGVEKYEASLEAEAAEDVKSHEE

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Crispr_ID: NZ_LT899687_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT899687_3

1647502-1647819

Orphan

Consensus_repeat	Method
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGT	CRT

5 spacers

The CRISPR arrays of NZ_LT899687_3

>merge|NZ_LT899687|3|1647502-1647819|CRT
TTGACTTCTTAGCAGTCTTAGCTGCCTTCTTGGTGTTCTTAGCAGCCTTCTTAGTTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGTCCTTAGCAGCCTTCTTAGTTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGTTCTTAGCAGCCTTCTTAGTTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGTCCTTAGCAGCCTTCTTAGTTGACTTCTTAGTTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGTCCTTAGCAGCCTTCTTAGTTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTAG

>NZ_LT899687|3|2|1647502-1647819|CRT
TTGACTTCTTAGCAGTCTTAGCTGCCTTCTTGGTGT	TCTTAGCAGCCTTCTTAG
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGT	CCTTAGCAGCCTTCTTAG
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGT	TCTTAGCAGCCTTCTTAG
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGT	CCTTAGCAGCCTTCTTAGTTGACTTCTTAG
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTGT	CCTTAGCAGCCTTCTTAG
TTGACTTCTTGGTAGTCTTAGCTGCCTTCTTGGTAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT899687.1\|WP_064081774.1\|1644840_1645854_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|234629
NZ_LT899687.1\|WP_089120060.1\|1640874_1642038_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|181811
NZ_LT899687.1\|WP_089120059.1\|1638327_1639104_-\|DUF4422-domain-containing-protein	unknown	unknown	gnl\|CDD\|379595
NZ_LT899687.1\|WP_089120062.1\|1643982_1644243_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT899687.1\|WP_089120058.1\|1634830_1635736_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133028
NZ_LT899687.1\|WP_089120037.1\|1649708_1650767_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|182223
NZ_LT899687.1\|WP_089120068.1\|1657215_1657920_-\|aquaporin-family-protein	unknown	unknown	gnl\|CDD\|223653
NZ_LT899687.1\|WP_089120069.1\|1657921_1658299_-\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	unknown	unknown	gnl\|CDD\|184702
NZ_LT899687.1\|WP_089120071.1\|1658895_1659891_-\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
NZ_LT899687.1\|WP_089120173.1\|1643487_1643802_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT899687.1\|WP_089120070.1\|1658300_1658882_-\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
NZ_LT899687.1\|WP_089120064.1\|1654678_1654990_-\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NZ_LT899687.1\|WP_011544253.1\|1654164_1654590_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LT899687.1\|WP_011544242.1\|1637191_1638307_-\|UDP-galactopyranose-mutase	unknown	unknown	gnl\|CDD\|223636
NZ_LT899687.1\|WP_041806691.1\|1639120_1639717_-\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NZ_LT899687.1\|WP_003621442.1\|1644344_1644704_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_LT899687.1\|WP_089120066.1\|1655630_1656608_-\|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|224013
NZ_LT899687.1\|WP_041813423.1\|1647000_1647378_+\|luciferase	unknown	unknown	gnl\|CDD\|274657
NZ_LT899687.1\|WP_003620235.1\|1651816_1652002_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT899687.1\|WP_089120067.1\|1656679_1657204_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274100

Protein	Function_ID	Function_description	E-value
NZ_LT899687.1\|WP_064081774.1\|1644840_1645854_-\|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|234629	PRK00094, gpsA, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.	4.03564e-158
NZ_LT899687.1\|WP_089120060.1\|1640874_1642038_-\|LCP-family-protein	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	1.63825e-66
NZ_LT899687.1\|WP_089120059.1\|1638327_1639104_-\|DUF4422-domain-containing-protein	gnl\|CDD\|379595	pfam14393, DUF4422, Domain of unknown function (DUF4422). This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 255 and 371 amino acids in length.	2.97891e-115
NZ_LT899687.1\|WP_089120058.1\|1634830_1635736_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133028	cd04185, GT_2_like_b, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.19404e-76
NZ_LT899687.1\|WP_089120037.1\|1649708_1650767_+\|glycosyltransferase	gnl\|CDD\|182223	PRK10073, PRK10073, putative glycosyl transferase; Provisional.	1.31937e-28
NZ_LT899687.1\|WP_089120068.1\|1657215_1657920_-\|aquaporin-family-protein	gnl\|CDD\|223653	COG0580, GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism].	1.23128e-65
NZ_LT899687.1\|WP_089120071.1\|1658895_1659891_-\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
NZ_LT899687.1\|WP_089120070.1\|1658300_1658882_-\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	5.4179e-80
NZ_LT899687.1\|WP_089120069.1\|1657921_1658299_-\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	7.96716e-43
NZ_LT899687.1\|WP_011544253.1\|1654164_1654590_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.09852e-88
NZ_LT899687.1\|WP_089120064.1\|1654678_1654990_-\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	1.18396e-26
NZ_LT899687.1\|WP_041806691.1\|1639120_1639717_-\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	6.19791e-87
NZ_LT899687.1\|WP_003621442.1\|1644344_1644704_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.66568e-15
NZ_LT899687.1\|WP_089120066.1\|1655630_1656608_-\|dTDP-glucose-4,6-dehydratase	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NZ_LT899687.1\|WP_011544242.1\|1637191_1638307_-\|UDP-galactopyranose-mutase	gnl\|CDD\|223636	COG0562, Glf, UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane].	1.88472e-180
NZ_LT899687.1\|WP_041813423.1\|1647000_1647378_+\|luciferase	gnl\|CDD\|274657	TIGR03571, lucif_BA3436, luciferase-type oxidoreductase, BA3436 family. This family is a distinct subgroup among members of the luciferase monooxygenase domain family. The larger family contains both FMN-binding enzymes (luciferase, alkane monooxygenase) and F420-binding enzymes (methylenetetrahydromethanopterin reductase, secondary alcohol dehydrogenase, glucose-6-phosphate dehydrogenase). Although some members of the domain family bind coenzyme F420 rather than FMN, members of this family are from species that lack the genes for F420 biosynthesis. A crystal structure, but not function, is known (but unpublished) for the member from Bacillus cereus, PDB\|2B81. [Unknown function, Enzymes of unknown specificity].	6.94318e-25
NZ_LT899687.1\|WP_089120067.1\|1656679_1657204_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	6.36851e-28

>NZ_LT899687.1|WP_041813423.1|1647000_1647378_+|luciferase
MPLVAIGRCRQDLSWLANEPDAWIWHGIGEDETAPAVKKLNDLNEDGNWHPFGYQNFVELLDDPDAPCELFNKIYLRGGAKSMAQFWRKQREEGLNHVIINFKPTKRPIADCLADMDVFPEVNKD
>NZ_LT899687.1|WP_064081774.1|1644840_1645854_-|NAD(P)-dependent-glycerol-3-phosphate-dehydrogenase
MAKIGVLGAGTWGMALARMLSNSGHEVTVWSALPQEVDELSRTRRQKNLPGMVIPDEIKFTKEIAEACQDKDIILFAVPSVFVRSTAKTAAAFIPDGQIIVDVAKGIEPDTLLTLTEVIADELNKDGKHGNVHYVAMSGPTHAEEVAKDLPTTIVSACEDQAVAKKVQDVFMNKNMRVYTNYDRLGVELCGALKNVIALASGICSGLGYGDNMRAALIIRGMAEIKRLGLKMGGKEDSFDGLAGMGDLIVTATSKESRNNNAGYLIGKGKSAEEAKKEVGMVVEGINAIPAALELADKYDVEMPIVFAVDAVVNRGADARETVDALMLREKKSEMTK
>NZ_LT899687.1|WP_003621442.1|1644344_1644704_-|helix-turn-helix-transcriptional-regulator
MEKNMIGKYLRDLRRRRGMSQQELALALGVSKQTISNWEVGRKVPRMKAVDKIANIFGVSRNSILAGLPVEMLEQADRRVVDLTDRDIRLTYLGQQVPREYIDIIEKLMRWDIAERDAQ
>NZ_LT899687.1|WP_089120062.1|1643982_1644243_-|hypothetical-protein
MMKEKNWLTWLTVLALVVGFAAMGASVWLSAQAAKQTQRNSQLAGQLYQASRTKSQEASNIKKRLDKLASDNSSLKKKNSRLAKEN
>NZ_LT899687.1|WP_089120173.1|1643487_1643802_-|hypothetical-protein
MPSYFPVGGVKPRYFYRKKVAIGGTEGSLTGAYAGSDMVCLFADASGVYWFKGNRGQIEKIGSQAHFKKLLRQISLNKLEESPLPVKKMKTEKKKTSKKKKEES
>NZ_LT899687.1|WP_089120060.1|1640874_1642038_-|LCP-family-protein
MDKNTRVGKRKKRNKAMRIFWSVMAVILVAIGGFALYEYNTVKNAADTAYRSGGLGNAENGSKNSVISNSKPIAILLMGTDTGALGRTYKGRTDSIMVAVLNPKTKKTTLVSFERDQQVNLPDYPENSPSKLNAAYAYGNAKELAKVLKKYYNIPINAYVLINMGGLKTIVNKVGGVDIAPILSFSYEGYTFTKGKTTHMDGAKALAYSRMRYDDPEGDYGRQKRQRQVLSALLKKAESATTLLNPSFISSLSKQVQTDLTFSDMTSMAKRYLAATKDLKTDYTHGTSYMQDGVSYQKISVSERQRISNLIRKTLGLKTKTVSTDSIDTSTSSSSSSSSTTTDSDTTGGAGNTAGPSDNGAAAGNGADSGTTGGYSAGNDQNNSTGY
>NZ_LT899687.1|WP_041806691.1|1639120_1639717_-|sugar-transferase
MKRFLDIVGSLLALIVFSPVFLVLSLLIKSRDGGSAFFAQERIGKGGKSFKMYKFRSMKMNAEEILKSDPELYQKYVANDYKLLADEDPRITPIGRWMRRTSVDELPQFVNILKGDMSIIGPRPVVEKELAEYGNRKDKFLSVRPGAMGLWQATGRSNISYPERCDVELEYIDNISFTYDVKIFFQTIFSIFKKEGAY
>NZ_LT899687.1|WP_089120059.1|1638327_1639104_-|DUF4422-domain-containing-protein
MKIKVLVAAHKQFPMPDDSVYLPVLVGAVKNYKAGIAYRRDDEGDNISARNPYYSELTGIYWAWKNLKDFDAIGLVHYRRYFYVSKPHDLDHVAKGADYEHFLADHDVIVPKKRNYYIESNYDHYIHAHPAEPLDKTRDIIADAYPDYLPAFDMMMKRRSAHMFNMFVMKRPAFESYCEFVFGVLSKLEGQIDISGYSVQDQRVYGYISERLLDVWLYTTKQDFVEMPWGQIGGEAVIKKGYNLIKRKLGIGKKQTHF
>NZ_LT899687.1|WP_011544242.1|1637191_1638307_-|UDP-galactopyranose-mutase
MSKYLVVGAGLFGAVFAREAAKRGHEVTVIEKRDHIAGNIYTKEIDGIQVHQYGAHIFHTSNKEVWEYVQQFAEFNRYTNSPVANYKGKMYNLPFNMNTFTQMWGVRTPQEAIDKINEQRAEMAGKTPQNLEEQAISLIGRDIYEKLIKGYTEKQWGRKATELPAFIIKRVPVRLIYDNNYFNDDYQGIPKGGYTKLVENMLKDDKITVELDTDFFAKKDEYLQKFDRVVYTGPIDEFFDYKLGELEYRSLRFETEEKNVGNYQGNAVINYTDAETPYTRVIEHKHFEFGKGDPDKTIITREYPADWHKGDEPYYPVNNDRNNDLYAQYKEMADKEDAKVIFGGRLGQYKYYNMDQVIAAALEAVNEEFGK
>NZ_LT899687.1|WP_089120058.1|1634830_1635736_-|glycosyltransferase-family-2-protein
MKSVAAVVVTYNRKELLREAIDALLMQSAAEADVLVVDNASTDGTKDYIADYIDQGQIIYINTGENLGGAGGFNFGMRKACEAGYKYVWLMDDDAIVKRDALKELLKADQLLKGNYGYLSSTVFWTDGQPCVMNRPKLVKDWTSDLGYLSAGLVRTYYSTFVSFFVKTATVKELGLPIKDFFIWGDDVEYSNRLSKKYPCYVVGKSQVIHKTRDNNGSNIAKEQGDRIGRYKFAYRNECVIARENGMNGRLRQFAKVNYNMLRVIFTHNPHKLKKLGIILGGSVEGIFFRPEIEYIEEQHD
>NZ_LT899687.1|WP_089120037.1|1649708_1650767_+|glycosyltransferase
MSIKTRLKHTLGVVAPLIRVRSKMSREAAENLLTAYSPDPNTTCVAHNKIDKKYDLHIIVACYNVENFIVECLDSIMNQDTKYSYIVTAVNDGSTDRTGEILNKYVKNYPDKLEVITQENKGLSGARNSALRWIKGRYVTFVDSDDVLTPNAVESLMEHAEDITQGNYYNFRVDLKGDVQRQAILATQLSGFPWGKVFKSEILANFQFPEGYWFEDTPISCIMYGMGYRMNMIQDIVYGYRLNPNGISATAPHSKRSIETWYITKKCYEEYPAFGVDYDQRAYDYFLKQCITNEKRTRHQPPKIREAIFTLEYELMKKYFASFSTQDSSLKRTEAALKKRLFVAFELLACAE
>NZ_LT899687.1|WP_003620235.1|1651816_1652002_+|hypothetical-protein
MQFTKQFEGTFAQVKEQIDKFVAEGGHIDAVITDHTSEKVTENHTFSYKMRVIAICSEEES
>NZ_LT899687.1|WP_011544253.1|1654164_1654590_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MNEKADLKDRLTPMQYDVTQNAATEPPYTGEYDDFFEKGIYVDVVSGEALFSSLDKYDSGCGWPAFTKPLVKLTQRRDQSFGMERTEVRSRQADSHLGHVFTDGPLDRGGLRYCINSAALKFIPYDQLEEAGYGEYRQLFE
>NZ_LT899687.1|WP_089120064.1|1654678_1654990_-|HigA-family-addiction-module-antidote-protein
MTESIKTPTVAETINDEYLQPLGLSAADLAQAIHVPAARIKDILHGSQEITADISLRLAKFFGVSDAYFLNLQSDIDLRDAKKHLSRDLSAIKPFTEVQAKNK
>NZ_LT899687.1|WP_089120066.1|1655630_1656608_-|dTDP-glucose-4,6-dehydratase
MKIIVTGGAGFIGSNFVFYMMKKHPDYKIICLDKLTYAGNLSTLKDVMDKPNFRFVKLDICDREGVYKLFEEEHPDVVVNFAAESHVDRSIENPEIFLQTNIIGTSVLMDACRKYGIKRYHQVSTDEVYGDLPLDRPDLFFHEDTPLHTSSPYSSSKASADLLVGAYGRTYGLPVTISRCSNNYGPYQFPEKLIPLMIQRALDDKPLPVYGEGQNVRDWLYVEDHCKAIDLILEKGTVGEVYNIGGHNEMHNIDIVKLICDYLDKPYSLIEHVTDRKGHDQRYAIDPTKIHDELGWLPETMFKDGIKKTIQWYLDNKEWWENIIS
>NZ_LT899687.1|WP_089120067.1|1656679_1657204_-|TetR-family-transcriptional-regulator
MTECLKLHISQVFKDEVAKNGFNHVSVAKIMKKSGIRRQTFYENFKDKFDLLDYTIKSMMENDIESNISYLDWEGIIFLVFYEIELNKRFYKSVYESQTEVDVVGEISSHIAVLLKQIIEEEGADFDQQAKDFVETFCLGLTYTMIDNLFRPHPLEYDVIASKVDHALHFTLNL
>NZ_LT899687.1|WP_089120068.1|1657215_1657920_-|aquaporin-family-protein
MNGFLGEFLGTMILIVLGVGCGAGISLNKAYAKGQGWLFVTLAWGMGVTFGVYVAGQFGAQGHLNPAVTIGFAAFGFFPWSQVMPYLLGQFLGAFVGAALVILHYYPHFKATKADEGNSVGIFATGPAINNPVFNFLSETIATFVFIFTLLNLGNFTQGLKPLIVGFLIMVVGQALGSTTGFALNPARDFSPRLAYAILPVPNKGGANWAYAWVPVLGPIAGGLLASGLQALLK
>NZ_LT899687.1|WP_089120069.1|1657921_1658299_-|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM
MTYGILIVSHVPEIAAGLPKLLKQVAADVPITFAGGTDDGNIGTSMEKIGQSIEENAADELLAFYDLGSARMNLDMAGEFAEKKVRVYDVALIEGSYVAASLLQAGVGLAELESQLAPLKIKGDD
>NZ_LT899687.1|WP_089120070.1|1658300_1658882_-|dihydroxyacetone-kinase-subunit-L
MELTTELLDKWMAIFAEKIEANKAYLSDLDTPIGDGDHGNNMARGMSAVEEALQTKKPADLTSALKLVAMSLISKVGGASGPLYGTAFLEMAKLSNSETDLAKLTEAALLGIKKRGGAEPGDKTMVDVWSAVVPALAKGNLTNDLIQEAVESTKPMQAKKGRASYLGERSIGHLDPGSVSSGYLFTALLEAEA
>NZ_LT899687.1|WP_089120071.1|1658895_1659891_-|dihydroxyacetone-kinase-subunit-DhaK
MKKIINDPSNVVEEMVTGLARMYPQYVERIPGTAALVRSDKDSMTGKVGLVSGGGSGHEPAHAGYVGKGMLTAAVCGQVFTSPTPDQIYEAIKAADQGKGVFLIVKNYSGDVMNFDMAKDLAAMDDIEVRSIVVDDDIAVENSLYTQGRRGVAGTVFMHKILGAAADQGASLDEIEELAKAVLPHINTIGVALSAATVPEVGKPGFVLADDEIEYGVGIHSEPGYRREKIKPSKDLAQELLSKIDESLKLSAEKKYAILVNGMGATPLMEQYIFSKDVLDWLGAKGIKPVFTKAGNYMTSIDMAGISLTVMEIADDKWLYYLNYPVKTIAW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT899687_1	1.1\|297985\|30\|NZ_LT899687\|CRISPRCasFinder	297985-298014	30	NZ_LT899687.1	297931-297960	0	1.0
NZ_LT899687_3	3.1\|1647538\|18\|NZ_LT899687\|CRT	1647538-1647555	18	NZ_LT899687.1	1647484-1647501	1	0.944
NZ_LT899687_3	3.3\|1647646\|18\|NZ_LT899687\|CRT	1647646-1647663	18	NZ_LT899687.1	1647484-1647501	1	0.944
NZ_LT899687_3	3.1\|1647538\|18\|NZ_LT899687\|CRT	1647538-1647555	18	NZ_LT899687.1	66753-66770	2	0.889
NZ_LT899687_3	3.1\|1647538\|18\|NZ_LT899687\|CRT	1647538-1647555	18	NZ_LT899687.1	67116-67133	2	0.889
NZ_LT899687_3	3.1\|1647538\|18\|NZ_LT899687\|CRT	1647538-1647555	18	NZ_LT899687.1	1748074-1748091	2	0.889
NZ_LT899687_3	3.3\|1647646\|18\|NZ_LT899687\|CRT	1647646-1647663	18	NZ_LT899687.1	66753-66770	2	0.889
NZ_LT899687_3	3.3\|1647646\|18\|NZ_LT899687\|CRT	1647646-1647663	18	NZ_LT899687.1	67116-67133	2	0.889
NZ_LT899687_3	3.3\|1647646\|18\|NZ_LT899687\|CRT	1647646-1647663	18	NZ_LT899687.1	1748074-1748091	2	0.889

1. spacer 1.1|297985|30|NZ_LT899687|CRISPRCasFinder matches to position: 297931-297960, mismatch: 0, identity: 1.0

ggataacctccgttatgtggatttacatgt	CRISPR spacer
ggataacctccgttatgtggatttacatgt	Protospacer
******************************

2. spacer 3.1|1647538|18|NZ_LT899687|CRT matches to position: 1647484-1647501, mismatch: 1, identity: 0.944

tcttagcagccttcttag	CRISPR spacer
tctttgcagccttcttag	Protospacer
**** *************

3. spacer 3.3|1647646|18|NZ_LT899687|CRT matches to position: 1647484-1647501, mismatch: 1, identity: 0.944

tcttagcagccttcttag	CRISPR spacer
tctttgcagccttcttag	Protospacer
**** *************

4. spacer 3.1|1647538|18|NZ_LT899687|CRT matches to position: 66753-66770, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

5. spacer 3.1|1647538|18|NZ_LT899687|CRT matches to position: 67116-67133, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

6. spacer 3.1|1647538|18|NZ_LT899687|CRT matches to position: 1748074-1748091, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

7. spacer 3.3|1647646|18|NZ_LT899687|CRT matches to position: 66753-66770, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

8. spacer 3.3|1647646|18|NZ_LT899687|CRT matches to position: 67116-67133, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

9. spacer 3.3|1647646|18|NZ_LT899687|CRT matches to position: 1748074-1748091, mismatch: 2, identity: 0.889

tcttagcagccttcttag	CRISPR spacer
tcttagtagtcttcttag	Protospacer
******.**.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT899687_2	2.3\|751774\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751774-751803	30	EU409559	Lactobacillus phage JCL1032, complete genome	39673-39702	2	0.933
NZ_LT899687_2	2.10\|752236\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752236-752265	30	MK448924	Streptococcus phage Javan384, complete genome	11362-11391	3	0.9
NZ_LT899687_2	2.10\|752236\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752236-752265	30	MK448926	Streptococcus phage Javan392, complete genome	15247-15276	3	0.9
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	KU517658	Clostridium phage HM T, complete genome	23818-23847	4	0.867
NZ_LT899687_2	2.4\|751840\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751840-751869	30	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	1523813-1523842	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NZ_CP013822	Piscirickettsia salmonis strain PM25344B plasmid p1PS14, complete sequence	19918-19947	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812241	Flavobacterium phage vB_FspS_tooticki9-1, complete genome	32714-32743	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812210	Flavobacterium phage vB_FspS_hemulen9-1, complete genome	34732-34761	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812223	Flavobacterium phage vB_FspS_mumin6-4, complete genome	33679-33708	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812237	Flavobacterium phage vB_FspS_snusmum9-1, complete genome	34890-34919	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812228	Flavobacterium phage vB_FspS_mymlan6-2, complete genome	34177-34206	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812215	Flavobacterium phage vB_FspS_lillamy9-4, complete genome	34073-34102	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812216	Flavobacterium phage vB_FspS_lillamy9-5, complete genome	34073-34102	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NC_048835	Flavobacterium phage vB_FspS_lillamy9-1, complete genome	34073-34102	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812221	Flavobacterium phage vB_FspS_mumin6-2, complete genome	34332-34361	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812213	Flavobacterium phage vB_FspS_lillamy9-2, complete genome	34073-34102	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812230	Flavobacterium phage vB_FspS_sniff9-2, complete genome	33712-33741	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812209	Flavobacterium phage vB_FspS_hemulen6-2, complete genome	34861-34890	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812218	Flavobacterium phage vB_FspS_lillamy9-7, complete genome	33336-33365	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812233	Flavobacterium phage vB_FspS_snork9-1, complete genome	33889-33918	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812234	Flavobacterium phage vB_FspS_snusmum6-1, complete genome	35512-35541	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812236	Flavobacterium phage vB_FspS_snusmum6-3, complete genome	35512-35541	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812219	Flavobacterium phage vB_FspS_morran9-1, complete genome	34190-34219	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812217	Flavobacterium phage vB_FspS_lillamy9-6, complete genome	33812-33841	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NC_048840	Flavobacterium phage vB_FspS_snork6-1, complete genome	34019-34048	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NC_048844	Flavobacterium phage vB_FspS_tooticki6-1, complete genome	32714-32743	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812214	Flavobacterium phage vB_FspS_lillamy9-3, complete genome	34073-34102	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NC_048839	Flavobacterium phage vB_FspS_sniff9-1, complete genome	33939-33968	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	NC_048842	Flavobacterium phage vB_FspS_stinky9-1, complete genome	33551-33580	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812220	Flavobacterium phage vB_FspS_mumin6-1, complete genome	34332-34361	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812227	Flavobacterium phage vB_FspS_mymlan6-1, complete genome	34306-34335	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812225	Flavobacterium phage vB_FspS_mumin9-2, complete genome	34332-34361	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812232	Flavobacterium phage vB_FspS_snork6-2, complete genome	33537-33566	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812222	Flavobacterium phage vB_FspS_mumin6-3, complete genome	33829-33858	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812206	Flavobacterium phage vB_FspS_filifjonk9-1, complete genome	33833-33862	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812224	Flavobacterium phage vB_FspS_mumin9-1, complete genome	34332-34361	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812235	Flavobacterium phage vB_FspS_snusmum6-2, complete genome	35512-35541	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812208	Flavobacterium phage vB_FspS_hemulen6-1, complete genome	34870-34899	6	0.8
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN812226	Flavobacterium phage vB_FspS_mumin9-3, complete genome	34203-34232	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250021	Prevotella phage Lak-B2, complete genome	174359-174388	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250024	Prevotella phage Lak-B5, complete genome	168367-168396	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250028	Prevotella phage Lak-B9, complete genome	173250-173279	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250023	Prevotella phage Lak-B4, complete genome	174262-174291	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250025	Prevotella phage Lak-B6, complete genome	171560-171589	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250022	Prevotella phage Lak-B3, complete genome	171575-171604	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250027	Prevotella phage Lak-B8, complete genome	174473-174502	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250026	Prevotella phage Lak-B7, complete genome	174478-174507	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK250020	Prevotella phage Lak-B1, complete genome	173230-173259	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	44231-44260	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NZ_CP022346	Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence	48239-48268	6	0.8
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NZ_CP023246	Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence	359646-359675	6	0.8
NZ_LT899687_2	2.2\|751708\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751708-751737	30	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	71827-71856	7	0.767
NZ_LT899687_2	2.2\|751708\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751708-751737	30	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	16284-16313	7	0.767
NZ_LT899687_2	2.4\|751840\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751840-751869	30	KY707339	Pseudomonas phage JBD68, complete genome	11005-11034	7	0.767
NZ_LT899687_2	2.5\|751906\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751906-751935	30	NZ_CP019737	Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-3, complete sequence	17910-17939	7	0.767
NZ_LT899687_2	2.5\|751906\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751906-751935	30	NZ_CP019746	Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-3, complete sequence	23383-23412	7	0.767
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NZ_LR214942	Mycoplasma orale strain NCTC10112 plasmid 3	1412-1441	7	0.767
NZ_LT899687_3	3.4\|1647700\|30\|NZ_LT899687\|CRT	1647700-1647729	30	MN855764	Siphoviridae sp. isolate 508, partial genome	17003-17032	7	0.767
NZ_LT899687_2	2.4\|751840\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751840-751869	30	NZ_CP041653	Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence	146310-146339	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MF431732	Bacteriophage T5-like pork29, complete genome	92591-92620	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	LR597659	Escherichia phage T5_ev212 genome assembly, chromosome: 1	90048-90077	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MT653146	Salmonella phage 8sent1748, complete genome	91725-91754	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MF431731	Bacteriophage T5-like pork27, complete genome	92590-92619	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	KY775453	Salmonella phage Stp1 contig.00003 genomic sequence	50569-50598	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	AY543070	Bacteriophage T5, complete genome	92008-92037	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MT311645	Salmonella phage vB_Sen-E22, complete genome	63094-63123	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK972716	Salmonella phage SE8, complete genome	53903-53932	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MT233524	Salmonella phage vB_Sen_I1, complete genome	40888-40917	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	AY587007	Bacteriophage T5 strain ATCC 11303-B5, complete genome	92090-92119	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	AY692264	Bacteriophage T5 strain st0 deletion mutant, complete genome	83966-83995	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK373799	Escherichia phage vB_EcoS_EASG3, complete genome	91814-91843	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_048853	Phage NBEco001, complete genome	89917-89946	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_048855	Phage NBEco002, complete genome	90230-90259	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK373797	Escherichia phage vB_EcoS_HASG4, complete genome	91857-91886	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MF431733	Bacteriophage T5-like saus47N, complete genome	92591-92620	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_005859	Enterobacteria phage T5, complete genome	92008-92037	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MF431735	Bacteriophage T5-like poul124, complete genome	92600-92629	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	AP019559	Escherichia phage SP15 DNA, complete genome	91658-91687	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MN956514	Salmonella phage L6jm, complete genome	90083-90112	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK373792	Escherichia phage vB_EcoS_VAH1, complete genome	84693-84722	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MT653143	Salmonella phage 3sent1, complete genome	90328-90357	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_048857	Phage NBSal005, complete genome	29777-29806	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MH102285	Salmonella phage vB_SenS_PHB06, partial genome	10570-10599	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MG969412	UNVERIFIED: Salmonella phage GE_vB_N5, complete genome	27770-27799	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MN445182	Salmonella phage vB_SalS_SA001, complete genome	86465-86494	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_017969	Escherichia phage bV_EcoS_AKFV33, complete genome	90372-90401	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MF431734	Bacteriophage T5-like saus111K, complete genome	92591-92620	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_047881	Shigella phage SSP1, complete genome	47864-47893	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MN994502	Phage NBSal003, complete genome	27883-27912	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	KY114934	Salmonella phage SP01, complete genome	28221-28250	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_024139	Escherichia phage vB_EcoS_FFH1, complete genome	90288-90317	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_047885	Bacteriophage T5-like chee24, complete genome	92591-92620	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_031042	Salmonella phage NR01, complete genome	62017-62046	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MN022787	Salmonella virus VSe12, complete genome	91585-91614	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	MK972715	Salmonella phage SE11, complete genome	85779-85808	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	LN887948	Escherichia phage slur09 genome assembly slu09, chromosome : 1	41361-41390	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	NC_047979	Escherichia phage Gostya9, complete genome	83135-83164	8	0.733
NZ_LT899687_2	2.7\|752038\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	752038-752067	30	LR027384	Escherichia virus vB_Eco_mar004NP2 genome assembly, chromosome: 1	81997-82026	8	0.733
NZ_LT899687_2	2.6\|751972\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751972-752001	30	MN855880	Siphoviridae sp. isolate 369, complete genome	1892-1921	9	0.7
NZ_LT899687_2	2.3\|751774\|30\|NZ_LT899687\|PILER-CR,CRISPRCasFinder,CRT	751774-751803	30	NZ_CP039693	Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence	333968-333997	10	0.667

1. spacer 2.3|751774|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to EU409559 (Lactobacillus phage JCL1032, complete genome) position: , mismatch: 2, identity: 0.933

cctctgcttgtttaagcttgcttatcgttg	CRISPR spacer
cctcagcttgtttaagcttgctcatcgttg	Protospacer
**** *****************.*******

2. spacer 2.10|752236|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK448924 (Streptococcus phage Javan384, complete genome) position: , mismatch: 3, identity: 0.9

-cattgttaccacgctttctataaatccttc	CRISPR spacer
tcattctt-ccacgctttctataaatctttc	Protospacer
 **** ** ******************.***

3. spacer 2.10|752236|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK448926 (Streptococcus phage Javan392, complete genome) position: , mismatch: 3, identity: 0.9

-cattgttaccacgctttctataaatccttc	CRISPR spacer
tcattctt-ccacgctttctataaatctttc	Protospacer
 **** ** ******************.***

4. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to KU517658 (Clostridium phage HM T, complete genome) position: , mismatch: 4, identity: 0.867

-ccatagttaaaatctcctctttaaattaag	CRISPR spacer
accat-gttaaaatctcctctttcaataaaa	Protospacer
 **** ***************** *** **.

5. spacer 2.4|751840|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 6, identity: 0.8

ggcgccagcagagcgttatcgcgttgctca	CRISPR spacer
cgcgcaagcagagcgtgatcgcgtggtgca	Protospacer
 **** ********** ******* *. **

6. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013822 (Piscirickettsia salmonis strain PM25344B plasmid p1PS14, complete sequence) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
tatataactttatttcgtttacgcttgatg	Protospacer
.*  ************ ********* **.

7. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812241 (Flavobacterium phage vB_FspS_tooticki9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

8. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812210 (Flavobacterium phage vB_FspS_hemulen9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

9. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812223 (Flavobacterium phage vB_FspS_mumin6-4, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

10. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812237 (Flavobacterium phage vB_FspS_snusmum9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

11. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812228 (Flavobacterium phage vB_FspS_mymlan6-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

12. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812215 (Flavobacterium phage vB_FspS_lillamy9-4, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

13. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812216 (Flavobacterium phage vB_FspS_lillamy9-5, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

14. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048835 (Flavobacterium phage vB_FspS_lillamy9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

15. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812221 (Flavobacterium phage vB_FspS_mumin6-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

16. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812213 (Flavobacterium phage vB_FspS_lillamy9-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

17. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812230 (Flavobacterium phage vB_FspS_sniff9-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

18. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812209 (Flavobacterium phage vB_FspS_hemulen6-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

19. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812218 (Flavobacterium phage vB_FspS_lillamy9-7, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

20. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812233 (Flavobacterium phage vB_FspS_snork9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

21. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812234 (Flavobacterium phage vB_FspS_snusmum6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

22. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812236 (Flavobacterium phage vB_FspS_snusmum6-3, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

23. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812219 (Flavobacterium phage vB_FspS_morran9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

24. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812217 (Flavobacterium phage vB_FspS_lillamy9-6, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

25. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048840 (Flavobacterium phage vB_FspS_snork6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

26. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048844 (Flavobacterium phage vB_FspS_tooticki6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

27. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812214 (Flavobacterium phage vB_FspS_lillamy9-3, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

28. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048839 (Flavobacterium phage vB_FspS_sniff9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

29. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048842 (Flavobacterium phage vB_FspS_stinky9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

30. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812220 (Flavobacterium phage vB_FspS_mumin6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

31. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812227 (Flavobacterium phage vB_FspS_mymlan6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

32. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812225 (Flavobacterium phage vB_FspS_mumin9-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

33. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812232 (Flavobacterium phage vB_FspS_snork6-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

34. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812222 (Flavobacterium phage vB_FspS_mumin6-3, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

35. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812206 (Flavobacterium phage vB_FspS_filifjonk9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

36. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812224 (Flavobacterium phage vB_FspS_mumin9-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

37. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812235 (Flavobacterium phage vB_FspS_snusmum6-2, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

38. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812208 (Flavobacterium phage vB_FspS_hemulen6-1, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

39. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN812226 (Flavobacterium phage vB_FspS_mumin9-3, complete genome) position: , mismatch: 6, identity: 0.8

caattaactttatttcctttacgctttata	CRISPR spacer
aaattaactttatttactttacacttaact	Protospacer
 ************** ******.*** *.

40. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250021 (Prevotella phage Lak-B2, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

41. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250024 (Prevotella phage Lak-B5, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

42. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250028 (Prevotella phage Lak-B9, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

43. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250023 (Prevotella phage Lak-B4, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

44. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250025 (Prevotella phage Lak-B6, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

45. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250022 (Prevotella phage Lak-B3, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

46. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250027 (Prevotella phage Lak-B8, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

47. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250026 (Prevotella phage Lak-B7, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

48. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK250020 (Prevotella phage Lak-B1, complete genome) position: , mismatch: 6, identity: 0.8

ccatagt----taaaatctcctctttaaattaag	CRISPR spacer
----agtccaataaaatctccgctttaaattaac	Protospacer
    ***    ********** ***********

49. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 6, identity: 0.8

-ccatagttaaaatctcctctttaaattaag	CRISPR spacer
ttcat-tttaaattctcctctataaattaat	Protospacer
 .***  ***** ******** ********

50. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022346 (Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

-ccatagttaaaatctcctctttaaattaag	CRISPR spacer
ttcat-tttataatctcctctataaattaat	Protospacer
 .***  *** ********** ********

51. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023246 (Bacillus cereus strain HBL-AI plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
caacatatataatttcctctttaaattaag	Protospacer
* *.*  ** ***.****************

52. spacer 2.2|751708|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 7, identity: 0.767

tattaacaccgacaccgacggcccaaaccc	CRISPR spacer
catccccacccacaccgacggcccacacct	Protospacer
.**.  **** ************** ***.

53. spacer 2.2|751708|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 7, identity: 0.767

tattaacaccgacaccgacggcccaaaccc	CRISPR spacer
catccccacccacaccgacggcccacacct	Protospacer
.**.  **** ************** ***.

54. spacer 2.4|751840|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to KY707339 (Pseudomonas phage JBD68, complete genome) position: , mismatch: 7, identity: 0.767

ggcgcc----agcagagcgttatcgcgttgctca	CRISPR spacer
----cctcggagcagatcgttatcgcgttgcgga	Protospacer
    **    ****** **************  *

55. spacer 2.5|751906|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019737 (Lactobacillus brevis strain TMW 1.2108 plasmid pl12108-3, complete sequence) position: , mismatch: 7, identity: 0.767

----attgcttggttaagctagcagttgcgttat	CRISPR spacer
gagtattgc----ttaagctagcagttgagttga	Protospacer
    *****    *************** ***.

56. spacer 2.5|751906|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019746 (Lactobacillus brevis strain TMW 1.2111 plasmid pl12111-3, complete sequence) position: , mismatch: 7, identity: 0.767

----attgcttggttaagctagcagttgcgttat	CRISPR spacer
gagtattgc----ttaagctagcagttgagttga	Protospacer
    *****    *************** ***.

57. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214942 (Mycoplasma orale strain NCTC10112 plasmid 3) position: , mismatch: 7, identity: 0.767

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
ggatatttaaaatctcctcttaaaattcta	Protospacer
  *** *************** *****  .

58. spacer 3.4|1647700|30|NZ_LT899687|CRT matches to MN855764 (Siphoviridae sp. isolate 508, partial genome) position: , mismatch: 7, identity: 0.767

ccttagcagccttcttagttgacttcttag	CRISPR spacer
ttgcgtcagctttcttagttgacttcttag	Protospacer
.. .. ****.*******************

59. spacer 2.4|751840|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041653 (Streptomyces sp. RLB1-9 plasmid pRLB1-9.1, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgccagcagagcgttatcgcgttgctca	CRISPR spacer
ggcgccagcagtgcggtatcgcgggagacg	Protospacer
*********** *** *******  .  *.

60. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MF431732 (Bacteriophage T5-like pork29, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

61. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to LR597659 (Escherichia phage T5_ev212 genome assembly, chromosome: 1) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

62. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MT653146 (Salmonella phage 8sent1748, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

63. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MF431731 (Bacteriophage T5-like pork27, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

64. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to KY775453 (Salmonella phage Stp1 contig.00003 genomic sequence) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

65. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to AY543070 (Bacteriophage T5, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

66. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MT311645 (Salmonella phage vB_Sen-E22, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

67. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK972716 (Salmonella phage SE8, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

68. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MT233524 (Salmonella phage vB_Sen_I1, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

69. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to AY587007 (Bacteriophage T5 strain ATCC 11303-B5, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

70. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to AY692264 (Bacteriophage T5 strain st0 deletion mutant, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

71. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK373799 (Escherichia phage vB_EcoS_EASG3, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

72. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048853 (Phage NBEco001, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

73. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048855 (Phage NBEco002, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

74. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK373797 (Escherichia phage vB_EcoS_HASG4, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

75. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MF431733 (Bacteriophage T5-like saus47N, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

76. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_005859 (Enterobacteria phage T5, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

77. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MF431735 (Bacteriophage T5-like poul124, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

78. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to AP019559 (Escherichia phage SP15 DNA, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

79. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN956514 (Salmonella phage L6jm, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

80. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK373792 (Escherichia phage vB_EcoS_VAH1, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

81. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MT653143 (Salmonella phage 3sent1, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

82. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_048857 (Phage NBSal005, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

83. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MH102285 (Salmonella phage vB_SenS_PHB06, partial genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

84. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MG969412 (UNVERIFIED: Salmonella phage GE_vB_N5, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

85. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN445182 (Salmonella phage vB_SalS_SA001, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

86. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_017969 (Escherichia phage bV_EcoS_AKFV33, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

87. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MF431734 (Bacteriophage T5-like saus111K, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

88. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_047881 (Shigella phage SSP1, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

89. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN994502 (Phage NBSal003, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

90. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to KY114934 (Salmonella phage SP01, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

91. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_024139 (Escherichia phage vB_EcoS_FFH1, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

92. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_047885 (Bacteriophage T5-like chee24, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

93. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_031042 (Salmonella phage NR01, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

94. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN022787 (Salmonella virus VSe12, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

95. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MK972715 (Salmonella phage SE11, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

96. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to LN887948 (Escherichia phage slur09 genome assembly slu09, chromosome : 1) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

97. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NC_047979 (Escherichia phage Gostya9, complete genome) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

98. spacer 2.7|752038|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to LR027384 (Escherichia virus vB_Eco_mar004NP2 genome assembly, chromosome: 1) position: , mismatch: 8, identity: 0.733

ccatagttaaaatctcctctttaaattaag	CRISPR spacer
tcatagttaatttctcctctttaataacaa	Protospacer
.*********  ************    *.

99. spacer 2.6|751972|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to MN855880 (Siphoviridae sp. isolate 369, complete genome) position: , mismatch: 9, identity: 0.7

caattaactttatttcctttacgctttata	CRISPR spacer
tttttaccgttatttcctttacgcttaggg	Protospacer
.  *** * ***************** . .

100. spacer 2.3|751774|30|NZ_LT899687|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039693 (Agrobacterium larrymoorei strain CFBP5473 plasmid pAlCFBP5473, complete sequence) position: , mismatch: 10, identity: 0.667

cctctgcttgtttaagcttgcttatcgttg	CRISPR spacer
ggaacaattgtttaagcttggttatcgtgc	Protospacer
    .. ************* *******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

223772 : 240323

Planktothrix_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003619471.1\|223772_224816_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-19	32.2
WP_003619469.1\|224830_225784_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.6e-21	33.3
WP_089119703.1\|225865_226003_+	DUF975 family protein	NA	NA	NA	NA
WP_003622302.1\|226137_227451_-	aminopeptidase	R4TV59	Phaeocystis_globosa_virus	3.3e-62	32.7
WP_076026226.1\|227502_228816_-	aminopeptidase	R4TV59	Phaeocystis_globosa_virus	1.2e-62	33.5
WP_003619462.1\|228912_229338_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_011677979.1\|229565_230027_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_003622306.1\|230110_231400_-	adenylosuccinate synthase	L7Y4J5	Megavirus	1.6e-72	38.2
WP_003622309.1\|231585_232578_+	GMP reductase	Q4ZCY7	Staphylococcus_virus	1.8e-132	68.4
WP_060597826.1\|232706_234014_+	Y-family DNA polymerase	M1Q231	Streptococcus_phage	1.0e-87	40.8
WP_003619451.1\|234006_234366_+	hypothetical protein	E3W8I0	Leuconostoc_phage	7.8e-06	34.8
WP_089119704.1\|234422_235727_-	purine permease	Q9KX94	Enterobacteria_phage	4.8e-29	30.7
WP_013439051.1\|235756_236326_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_003619444.1\|236680_237838_+	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	4.1e-56	31.3
WP_003619442.1\|237837_239391_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.5e-18	30.2
WP_089119705.1\|239713_239965_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_003616793.1\|239951_240323_+	type II toxin-antitoxin system HicB family antitoxin	A0A0K2CZV4	Paenibacillus_phage	8.9e-21	45.6

DBSCAN-SWA_2

943522 : 1096910

119

Streptococcus_phage(17.95%)

protease,tRNA,integrase,transposase

attL 939536:939554|attR 1065628:1065645

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
939536:939554	attL	NA	NA	NA	NA
WP_041806500.1\|943522_944164_-\|integrase	tyrosine-type recombinase/integrase	A3F636	Streptococcus_phage	5.1e-24	34.9
939536:939554	attL	NA	NA	NA	NA
WP_041813527.1\|944498_944939_-	hydrolase	NA	NA	NA	NA
WP_035170348.1\|945027_945264_-	hypothetical protein	NA	NA	NA	NA
WP_011678263.1\|947585_947741_-	hypothetical protein	NA	NA	NA	NA
WP_080571456.1\|947737_948016_-	diguanylate cyclase	NA	NA	NA	NA
WP_089120162.1\|953917_955354_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_089119867.1\|955436_956111_-	TIGR00266 family protein	NA	NA	NA	NA
WP_014564936.1\|956234_956684_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_014564939.1\|957633_958698_+	DUF2399 domain-containing protein	NA	NA	NA	NA
WP_089119884.1\|958684_960205_+	hypothetical protein	NA	NA	NA	NA
WP_014564941.1\|960192_961164_+	hypothetical protein	NA	NA	NA	NA
WP_014564942.1\|961150_964903_+	chromosome segregation ATPase	NA	NA	NA	NA
WP_011678290.1\|964959_965331_-	hypothetical protein	NA	NA	NA	NA
WP_014564943.1\|965660_966305_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014564944.1\|966386_966563_+	hypothetical protein	NA	NA	NA	NA
WP_003624004.1\|966657_967296_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_080504231.1\|967347_967824_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.9e-07	33.3
WP_130183459.1\|967736_968063_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_014564946.1\|967998_968928_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_089119885.1\|969028_969466_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_089119886.1\|969832_970783_-	hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	1.3e-31	34.2
WP_014564948.1\|970969_971431_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_089119887.1\|971430_973158_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.6e-32	27.4
WP_089119888.1\|973157_974915_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.7e-41	24.5
WP_003618103.1\|974997_975306_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_089119889.1\|976910_977381_-	ribonuclease HI	A0A0H3UZB5	Geobacillus_virus	1.9e-15	31.4
WP_035169663.1\|977602_978085_-	hypothetical protein	NA	NA	NA	NA
WP_089119890.1\|978292_978559_-	N-acetyltransferase	NA	NA	NA	NA
WP_011678298.1\|978560_979280_-	HAD family hydrolase	M1H9H9	Acanthocystis_turfacea_Chlorella_virus	1.9e-06	24.6
WP_089119892.1\|980066_980807_-	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_035169668.1\|981255_982041_-	exonuclease	A0A1X9I5C8	Streptococcus_phage	1.5e-17	31.3
WP_157695661.1\|982045_982639_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_089119893.1\|982652_983426_-	hypothetical protein	NA	NA	NA	NA
WP_089119894.1\|983418_983991_-	GNAT family N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	1.6e-29	39.5
WP_035169673.1\|984120_984855_-	hypothetical protein	A0A0E3ICJ0	Synechococcus_phage	9.4e-06	34.4
WP_089119895.1\|984854_989303_-	Eco57I restriction-modification methylase domain-containing protein	A0A2H4UUH6	Bodo_saltans_virus	3.9e-22	21.2
WP_089120163.1\|989429_989657_-	hypothetical protein	NA	NA	NA	NA
WP_002880363.1\|990232_990427_-	hypothetical protein	NA	NA	NA	NA
WP_003623053.1\|990473_991322_-	LD-carboxypeptidase	NA	NA	NA	NA
WP_089119896.1\|991366_992791_-	RsmF rRNA methyltransferase first C-terminal domain-containing protein	NA	NA	NA	NA
WP_089119897.1\|992783_993758_-	hypothetical protein	NA	NA	NA	NA
WP_076026420.1\|993757_994498_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002880372.1\|994608_994806_-	hypothetical protein	NA	NA	NA	NA
WP_089119898.1\|994951_995563_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_089119899.1\|995641_996394_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_089119900.1\|996466_997321_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_060598026.1\|997547_998978_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_089119901.1\|999078_1000599_-	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_011543933.1\|1000602_1001526_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.1e-26	38.7
WP_003623037.1\|1001856_1002318_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_035169870.1\|1002768_1003188_+	3-beta hydroxysteroid dehydrogenase	NA	NA	NA	NA
WP_089119902.1\|1003249_1004161_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_089119903.1\|1004880_1006053_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_089119904.1\|1006322_1011797_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	1.2e-09	30.3
WP_089119905.1\|1013428_1014091_+	DedA family protein	NA	NA	NA	NA
WP_089119906.1\|1014394_1015411_+	aspartate--ammonia ligase	A0A1C9C5F0	Heterosigma_akashiwo_virus	1.2e-59	39.1
WP_089119852.1\|1015486_1016785_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-52	28.4
WP_081381927.1\|1016837_1018142_-\|transposase	ISL3-like element ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.4e-57	33.0
WP_089119907.1\|1018278_1019328_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	7.3e-52	35.2
WP_089119908.1\|1019650_1020874_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	5.1e-97	48.5
WP_089119909.1\|1022325_1025352_-	DUF4981 domain-containing protein	L0N6M2	Herpes_simplex_virus	6.4e-141	32.9
WP_089119910.1\|1025355_1027239_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_011544236.1\|1027854_1029078_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	8.7e-97	48.5
WP_089119911.1\|1031334_1031646_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_089119912.1\|1031825_1032662_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_003618238.1\|1032704_1033271_+	signal peptidase I	NA	NA	NA	NA
1033118:1033136	attR	NA	NA	NA	NA
WP_089119913.1\|1033340_1033526_+	hypothetical protein	NA	NA	NA	NA
1033118:1033136	attR	NA	NA	NA	NA
WP_064081700.1\|1033917_1035156_-	peptidase T	NA	NA	NA	NA
WP_089119914.1\|1035199_1035997_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_089119915.1\|1035989_1036682_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_089119916.1\|1036924_1037974_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	1.5e-52	35.2
WP_002878612.1\|1038077_1038518_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_089119917.1\|1038517_1039345_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_089119918.1\|1041023_1042103_-	5-methylcytosine-specific restriction endonuclease system specificity protein McrC	NA	NA	NA	NA
WP_089119919.1\|1042099_1044505_-	EVE domain-containing protein	K4I1H4	Acidithiobacillus_phage	8.4e-19	28.0
WP_089120164.1\|1044763_1044982_-	hypothetical protein	NA	NA	NA	NA
WP_089119920.1\|1045011_1045191_-	hypothetical protein	NA	NA	NA	NA
WP_089119921.1\|1045522_1045855_-	hypothetical protein	NA	NA	NA	NA
WP_089119922.1\|1045981_1049101_-	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.5e-65	28.2
WP_089119923.1\|1049090_1049738_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_089119924.1\|1049734_1050193_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_172825222.1\|1050192_1051164_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	6.4e-34	27.4
WP_089120166.1\|1051260_1051989_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_089119925.1\|1052443_1053976_-	SAM-dependent DNA methyltransferase	A0A2H4PQP4	Staphylococcus_phage	2.3e-54	30.8
WP_172825223.1\|1056142_1058440_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	8.5e-61	30.2
WP_014564987.1\|1059836_1061060_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.0e-97	48.7
WP_011678358.1\|1062351_1063488_-	sigma-70 family RNA polymerase sigma factor	G8CLC7	Synechococcus_phage	1.6e-36	35.9
WP_089119926.1\|1063523_1064645_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.9e-38	36.6
WP_060598051.1\|1064686_1065805_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	2.4e-37	38.1
WP_014565022.1\|1067647_1069714_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003618715.1\|1069706_1070618_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_011678362.1\|1070882_1071632_-	DNA repair protein RecO	NA	NA	NA	NA
WP_011543965.1\|1071631_1072537_-	GTPase Era	NA	NA	NA	NA
WP_003618710.1\|1072520_1072940_-	cytidine deaminase	NA	NA	NA	NA
WP_003618709.1\|1072941_1073466_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_060598272.1\|1073465_1074413_-	PhoH family protein	H6X2N1	Pseudomonas_phage	4.0e-49	48.8
WP_002880182.1\|1074566_1074743_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_003618707.1\|1074911_1075769_+	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_089119927.1\|1075828_1076098_-	hypothetical protein	NA	NA	NA	NA
WP_089119928.1\|1076163_1077048_-	YitT family protein	NA	NA	NA	NA
WP_081044841.1\|1078208_1078520_-	hypothetical protein	NA	NA	NA	NA
WP_060598055.1\|1078480_1078729_-	hypothetical protein	NA	NA	NA	NA
WP_003618701.1\|1078972_1080157_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_089119929.1\|1080337_1081648_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_157695662.1\|1082004_1082151_-	hypothetical protein	NA	NA	NA	NA
WP_002880191.1\|1082534_1083431_-	aldose 1-epimerase family protein	NA	NA	NA	NA
WP_089119930.1\|1083512_1084907_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A1B2IB03	Erwinia_phage	5.0e-32	26.2
WP_003618695.1\|1084909_1085443_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_014565032.1\|1085551_1086439_-	tyrosine recombinase XerC	S5W9T9	Leptospira_phage	1.4e-24	30.2
WP_089119931.1\|1086438_1087758_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_003618692.1\|1087898_1090082_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	2.7e-93	34.8
WP_003618691.1\|1090208_1091048_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	1.4e-29	37.4
WP_014565035.1\|1091146_1091917_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	9.5e-25	37.2
WP_003623895.1\|1091906_1092764_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_002880201.1\|1092838_1093069_-	YozE family protein	NA	NA	NA	NA
WP_011543974.1\|1093072_1093918_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.0e-19	45.0
WP_014565038.1\|1094051_1094714_+	hemolysin III family protein	NA	NA	NA	NA
WP_003618685.1\|1094739_1095930_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.4e-43	47.8
WP_003618684.1\|1096010_1096910_+	YitT family protein	M1Q1P6	Streptococcus_phage	1.8e-51	39.8

DBSCAN-SWA_3

1691938 : 1698806

Streptomyces_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089120097.1\|1691938_1692724_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.4e-07	36.9
WP_089120098.1\|1692769_1693528_-	C40 family peptidase	A0A0A8WF62	Clostridium_phage	1.4e-15	41.0
WP_089120099.1\|1694685_1695468_-	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	3.4e-14	42.7
WP_089120100.1\|1695679_1696153_-	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	1.4e-15	41.9
WP_003621168.1\|1696323_1697370_-	lactate dehydrogenase	M1H502	Paramecium_bursaria_Chlorella_virus	1.2e-27	29.7
WP_089120101.1\|1697653_1698139_-	C40 family peptidase	A0A2L1IW19	Streptomyces_phage	2.3e-16	41.1
WP_059217012.1\|1698263_1698806_-	AAA family ATPase	U5J9X2	Bacillus_phage	1.7e-12	35.4

DBSCAN-SWA_4

1822382 : 1830503

Lactobacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_089120134.1\|1822382_1823474_+	BMP family protein	A0A0A7DN02	Lactobacillus_phage	1.1e-79	47.1
WP_089120135.1\|1823524_1823959_-	hypothetical protein	NA	NA	NA	NA
WP_016396105.1\|1824001_1824412_-	hypothetical protein	NA	NA	NA	NA
WP_089120136.1\|1824454_1825495_+	protein kinase	A0A2I2L4J2	Orpheovirus	2.9e-08	32.1
WP_089120137.1\|1825589_1826186_+	DUF4352 domain-containing protein	A0A0P0IXE0	Lactobacillus_phage	2.4e-44	70.0
WP_077301049.1\|1826372_1827470_+	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	5.1e-80	46.0
WP_003623370.1\|1827785_1828871_+	BMP family protein	A0A0A7DN02	Lactobacillus_phage	9.5e-79	48.6
WP_003621701.1\|1828958_1830503_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.6e-13	26.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LT899687

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection