CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NZ_LT960782	Lactobacillus sakei strain J64 plasmid 2, complete sequence	0 crisprs	NA	0	0
NZ_LT960781	Lactobacillus sakei strain J64 chromosome 1	2 crisprs	csa3,cas3,DinG,DEDDh,WYL	1	7
NZ_LT960783	Lactobacillus sakei strain J64 plasmid 3, complete sequence	0 crisprs	NA	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT960781_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT960781_1

216383-216942

Orphan

Consensus_repeat	Method
TTAGATGTTTCAAATTGGGATAC	CRISPRCasFinder
ATTACCGAATTAGATGTTTCAAATTGGGATAC	PILER-CR

7 spacers

csa3

The CRISPR arrays of NZ_LT960781_1

>merge|NZ_LT960781|1|216383-216942|CRISPRCasFinder,PILER-CR
CTAAATAGTACGAATTGGGACACTTCTAATATTCAAAATATGAATAACACATTTTTCAATTGTACGGCCTTAACGAACTTAGATGTTTCAAAATGGCAGACGGCAAAAATGACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTTTTAGATGTTTCAAATTGGGATACCAGTCACGTTACTAATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAATTAGATGTTTCGAATTGGGATACAAGCCAAGTGACGACAATGGCTTATACTTTTTCGGGATGTTCAAGACTTGAAACCTTAGATGTCTCAAAATGGCAGCTCGGCAAAAATACATCGTTGTCTTACACGTTCAGCGGTGATCAAAGATTAACGCAGTTAGACGTTTCTAAGTGGCAAACCGCTAATGTGACGAATATGGCTTCAACATTTTCCGGGACTGTCGGTGTTAAGACTTTAGCGGTTAAAGATTGGCAGACCACTAAAGTGACAACCATGGTGGGCATGTTTGCCAAGAGTGGTGTTGATCAGTTAGAAATTGCTGATTGGGATAT

>NZ_LT960781|1|1|216383-216942|CRISPRCasFinder
CTAAATAGTACGAATTGGGACAC	TTCTAATATTCAAAATATGAATAACACATTTTTCAATTGTACGGCCTTAACGAAC
TTAGATGTTTCAAAATGGCAGAC	GGCAAAAATGACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTT
TTAGATGTTTCAAATTGGGATAC	CAGTCACGTTACTAATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAA
TTAGATGTTTCGAATTGGGATAC	AAGCCAAGTGACGACAATGGCTTATACTTTTTCGGGATGTTCAAGACTTGAAACC
TTAGATGTCTCAAAATGGCAGCT	CGGCAAAAATACATCGTTGTCTTACACGTTCAGCGGTGATCAAAGATTAACGCAG
TTAGACGTTTCTAAGTGGCAAAC	CGCTAATGTGACGAATATGGCTTCAACATTTTCCGGGACTGTCGGTGTTAAGACT
TTAGCGGTTAAAGATTGGCAGAC	CACTAAAGTGACAACCATGGTGGGCATGTTTGCCAAGAGTGGTGTTGATCAG
TTAGAAATTGCTGATTGGGATAT

>NZ_LT960781|1|1|216461-216633|PILER-CR
TTAGATGTTTCAAAATGGCAGACGGCAAAAAT	GACTAATCTGGGGAGTACCTTTTCACAATCGGGCATTACTGTTTTAGA
TGTTTCAAATTGGGATACCAGTCACGTTACTA	ATTTAAGTAGTACTTTTCTGAATACTAGTATTGCCGAATTAGA
TGTTTCGAATTGGGATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT960781.1\|WP_101377628.1\|222897_224817_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375450
NZ_LT960781.1\|WP_101377625.1\|206559_207168_+\|cadmium-resistance-transporter	unknown	unknown	gnl\|CDD\|226750
NZ_LT960781.1\|WP_076645435.1\|217303_219067_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_LT960781.1\|WP_101377631.1\|226250_226454_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT960781.1\|WP_076645441.1\|221336_221900_+\|DUF916-domain-containing-protein	unknown	unknown	gnl\|CDD\|368712
NZ_LT960781.1\|WP_025016105.1\|214413_215406_+\|choloylglycine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238303
NZ_LT960781.1\|WP_076645445.1\|222537_222801_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197670
NZ_LT960781.1\|WP_162296395.1\|203229_206067_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|275067
NZ_LT960781.1\|WP_076632438.1\|201555_202176_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187577
NZ_LT960781.1\|WP_076645437.1\|219140_220178_+\|DUF916-and-DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_LT960781.1\|WP_076645429.1\|207385_207871_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_LT960781.1\|WP_016264495.1\|210846_212970_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_LT960781.1\|WP_101377626.1\|207977_210566_+\|RND-family-transporter	unknown	unknown	gnl\|CDD\|223964
NZ_LT960781.1\|WP_076645443.1\|221954_222389_+\|DUF3324-domain-containing-protein	unknown	unknown	gnl\|CDD\|371730
NZ_LT960781.1\|WP_101377623.1\|202191_202710_+\|flavodoxin	unknown	unknown	gnl\|CDD\|180850
NZ_LT960781.1\|WP_056948687.1\|206141_206492_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NZ_LT960781.1\|WP_101377629.1\|224826_225816_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375451
NZ_LT960781.1\|WP_101377630.1\|225946_226249_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|366278
NZ_LT960781.1\|WP_101377627.1\|220396_221245_+\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NZ_LT960781.1\|WP_025016106.1\|213599_214217_-\|DUF1361-domain-containing-protein	unknown	unknown	gnl\|CDD\|369208

Protein	Function_ID	Function_description	E-value
NZ_LT960781.1\|WP_101377628.1\|222897_224817_+\|hypothetical-protein	gnl\|CDD\|375450	pfam17965, MucBP_2, Mucin binding domain. This domain is found in bacterial cell surface proteins that interact with mucins. The archetypal member of this family is the Mub-R5 B1 domain. This domain has a beta-grasp fold.	2.18473e-11
NZ_LT960781.1\|WP_101377625.1\|206559_207168_+\|cadmium-resistance-transporter	gnl\|CDD\|226750	COG4300, CadD, Predicted permease, cadmium resistance protein [Inorganic ion transport and metabolism].	1.08469e-51
NZ_LT960781.1\|WP_076645435.1\|217303_219067_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	3.52104e-14
NZ_LT960781.1\|WP_076645441.1\|221336_221900_+\|DUF916-domain-containing-protein	gnl\|CDD\|368712	pfam06030, DUF916, Bacterial protein of unknown function (DUF916). This family consists of several hypothetical bacterial proteins of unknown function.	1.68941e-30
NZ_LT960781.1\|WP_025016105.1\|214413_215406_+\|choloylglycine-hydrolase-family-protein	gnl\|CDD\|238303	cd00542, Ntn_PVA, Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal nucleophilic cysteine, as do other members of the Ntn hydrolase family to which PVA belongs. This nucleophilic cysteine is exposed by post-translational prossessing of the PVA precursor. PVA forms a homotetramer.	1.30921e-149
NZ_LT960781.1\|WP_076645445.1\|222537_222801_+\|hypothetical-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	7.82515e-05
NZ_LT960781.1\|WP_162296395.1\|203229_206067_+\|WxL-domain-containing-protein	gnl\|CDD\|275067	TIGR04226, Fimbrial_subunit_type_2, fimbrial isopeptide formation D2 domain. The Streptococcus Pneumoniae pilus backbone protein, RrgB, has three tandem domains with Lys-to-Asn isopeptide bonds, but these three regions are extremely divergent in sequence. This model represents the homology domain family of the D2 domain. It occurs just once in many surface proteins but up to twenty times in some pilin subunit proteins. Three of every four members have the typical Gram-positive C-terminal motif, LPXTG, although in many cases this motif may be involved in pilin subunit cross-linking rather than cell wall attachment. Proteins with this domain include fimbrial proteins with lectin-like adhesion functions, and the majority of characterized members are involved in surface adhesion to host structures.	3.36954e-07
NZ_LT960781.1\|WP_076632438.1\|201555_202176_+\|NAD(P)H-binding-protein	gnl\|CDD\|187577	cd05267, SDR_a6, atypical (a) SDRs, subgroup 6. These atypical SDR family members of unknown function have only a partial match to a prototypical glycine-rich NAD(P)-binding motif consensus, GXXG, which conserves part of the motif of extended SDR. Furthermore, they lack the characteristic active site residues of the SDRs. This subgroup is related to phenylcoumaran benzylic ether reductase, an NADPH-dependent aromatic alcohol reductase. One member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.01365e-54
NZ_LT960781.1\|WP_076645437.1\|219140_220178_+\|DUF916-and-DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	5.68398e-43
NZ_LT960781.1\|WP_076645429.1\|207385_207871_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.23948e-07
NZ_LT960781.1\|WP_016264495.1\|210846_212970_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_LT960781.1\|WP_101377626.1\|207977_210566_+\|RND-family-transporter	gnl\|CDD\|223964	COG1033, COG1033, Predicted exporters of the RND superfamily [General function prediction only].	3.57312e-109
NZ_LT960781.1\|WP_076645443.1\|221954_222389_+\|DUF3324-domain-containing-protein	gnl\|CDD\|371730	pfam11797, DUF3324, Protein of unknown function C-terminal (DUF3324). This family consists of several hypothetical bacterial proteins of unknown function.	8.35773e-16
NZ_LT960781.1\|WP_101377623.1\|202191_202710_+\|flavodoxin	gnl\|CDD\|180850	PRK07116, PRK07116, flavodoxin; Provisional.	1.2108e-26
NZ_LT960781.1\|WP_056948687.1\|206141_206492_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.3203e-14
NZ_LT960781.1\|WP_101377629.1\|224826_225816_+\|hypothetical-protein	gnl\|CDD\|375451	pfam17966, Mub_B2, Mub B2-like domain. This entry corresponds to the Mub B2 domain. This domain is related to the Mub B1 domain pfam17965. This domain may be involved in mucin binding. This domain is often found associated with the related pfam17965 in bacterial cell surface proteins.	5.46026e-17
NZ_LT960781.1\|WP_101377630.1\|225946_226249_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|366278	pfam00746, Gram_pos_anchor, LPXTG cell wall anchor motif.	0.000120378
NZ_LT960781.1\|WP_101377627.1\|220396_221245_+\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	1.53025e-05
NZ_LT960781.1\|WP_025016106.1\|213599_214217_-\|DUF1361-domain-containing-protein	gnl\|CDD\|369208	pfam07099, DUF1361, Protein of unknown function (DUF1361). This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although some members are annotated as being putative integral membrane proteins.	1.89048e-27

>NZ_LT960781.1|WP_025016105.1|214413_215406_+|choloylglycine-hydrolase-family-protein
MCTSLTYSTVDGHHFLARTMDFSFELNGNPLFLPRQHQWQPVLEKQAIQNQYALMGAGAKLGDQYLVADGFNEHGLGCAELYFAHAAVYEPQPVPNKLNLVAEEFIVWVLGNYQTLEEVAADLDNVRIIESDQGVMGANQPLHWILSDRSGKTMVIEPRGNGLQLIDDPVGVMTNTPDLDWHIKNLSNYLNLQPQPFMERPFGNYQAGPFSQGTGTQALPGSYTPPDRFVRAAYSRQYMPEANNVAEGVNHILHILDNVTIPKGVNIGSGGSSDYTQYQGISGLNNLAYYMVNYDNRHVYQTNLTTDLIENQKEPVIYHLPQGQQNTILN
>NZ_LT960781.1|WP_025016106.1|213599_214217_-|DUF1361-domain-containing-protein
MSKKVLTIHAIILLFFALILLYQSRFAFLIWNIILALIPFDLSLLGRLFKNSRWRYLIGVVWLLFFPNALYMITDFSHLSSIGVGLSTAFQFVEYAILAGGIFVGVTLGLTSLFILYPLFIPNYQRLVNQAATFGVLSVCSSVAIYIGRFLRINSWDVFYQLHTTIASVLGVLNQSDFWIFVIAFSILQLILMLMGYQLAQLDDL
>NZ_LT960781.1|WP_016264495.1|210846_212970_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MANMYGNDPFFNNDMDDIFNQVFRRMGNSESARYVINGRELSPDEFAQYRATGKLPNREKEIEIKQNGEHALKKGGILEKLGRNLTQEARDGLLDPVIGRYNEIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQEIVAGKVPETIKDKEIYSIDLSSLEAGTQYRGSFEENIKNLIKEVKAAGNVILFFDEIHQILGIGSTGGEDGGKGLADIIKPALSRGELTVIGATTQDEYRNTILKNAALARRFNDVLVNEPSAADTVKILQGIKGLYEKHHHIELPDDVLKAAVDYSVQYIPQRTLPDKAIDLLDMTAAHLAAKRPETDKAKLAAELKQLEADKAEAVEAENYQAAEDLKVRIEKIKTQLENNDQHAAVMIATVDDIAQSVERLTGIPVAKMGSNDIQRLKNLGQRLKDKVIGQDEAVEMVARAIRRNRAGFSEGNQPIGSFLFVGPTGVGKTELAKQLALDMFGNKEAIIRLDMSEYADRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLFDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIDFKNTVIIATSNAGFGNEKLTMNDQEDAKLLDKLAPYFRPEFLNRFNGIVEFTHLTKADLSQIVDLMLTNVEQTLAKKELTLVVSKEAKDWLMEEGYDEAMGARPLRRVIEQQIRDKVTDFYLDHADVKDLKADLVDDQIVIQAVDSEN
>NZ_LT960781.1|WP_101377626.1|207977_210566_+|RND-family-transporter
MTNRFFTKISQIIHNNPIKVIIAVVLLTIGLAFGLPNIQMNMGNEVFVDTNSQVYKDTKTYQENFGGGSAYVLISGDQDQIVTHTTMKKVAALENKINKVDHIRSSTSVVSLLNQELESNAASTMGGNAKGSDKLQKDLMANLTTSQKTALQTKLQASLTPEQQQQMGQYGLSLLTPQQKMAAAQAGNQSPATLMKQLDKTQQVKVQQYLFTILNQDQQQMLQKQMLADLPKVEHMSTALLRDLMLDSKGHVRSQLSALLPKNGQNLLIMANMAAKTDMTTNVQVVHDVRHDIKQAGFQSDLKVRLAGNPVIMGGIQPLVMKTMATMLVLAVIIMVVVLFVVFPVRRRLLSLCYVLLGLIWTFGIMGWLHIDLTLATMATLPIIIGLGTDFGVQFHNRYEEEFHKSASGEQATKRAIKTMGPAVGVALIVMVFSFLTMFLSKAPMMQQFGLTLAIGVAAAYVVEFLLMFSSFALLDRKSKTTAKPQSAPKTSGLAKALRKYAQFVIKHAKILTLVGIILAATGFSVEGRIPIETNLTKLIPQDMQALKDTKYLQKQVGSTTYMTYLVKADDVRDKAVLAKTTQFANRENHKYQDIVGVTTLDSTYRQMGGTPKQQTQTEINEGIKTIPGTIRGTMLSKNNHYTMVQFKVDRSLTTGQQRTLMHHINRDLKHHATTLDVHPAGDSVMMLVGVGNMVANHTLIILAGLAIIAIILIAVYRDLKMALLSILPIAIVLGLSPLTLHLLGESYNPLTIALSSLVLGVGTEFTILILERFKEEQQLGKSTEEAIIVAVTNVGQAITASGLTVIGGFAALVFTSFPVLSSFGLITVLDTVYSLIAALTILPAMIVISDKWFGGSKNKAK
>NZ_LT960781.1|WP_076645429.1|207385_207871_-|TetR/AcrR-family-transcriptional-regulator
MTKGEQTRQKIIEATVALMLSDTRASVSHIIKQAHVSRTTFYRHFPSLGDAILAATLTRFTTSYQSITDPAELLELVINTLDQDLAFFVHFSVYKEEFDFLFKQLFFKVANNVQITLLDRTPVNDELVYRAISGIVAGWMTNTTTIKAADVKGFIQQVLNL
>NZ_LT960781.1|WP_101377625.1|206559_207168_+|cadmium-resistance-transporter
MQTAILTGITAYISTSIDYLIILMVIFGSVNRKERRLVYWGDLLGTSVLVAASLVMAFILGFVPQEWLLGLLGIIPVLMGLRLLISGESDDDEVVESQMKKRRNIIMNVAIITIATCGTDNTGIYVPIFAQSTVQTLAVILITFFFMLSLFCYVGYLLIKIPKVAEILERYGMYITAIVYIGLGLYIMFESGTVQHLVKMLG
>NZ_LT960781.1|WP_056948687.1|206141_206492_-|winged-helix-turn-helix-transcriptional-regulator
MLKNEAIPLNTINLIPERNLEESKRILKLLSNPTRLQLLHILAQRECNVSELGELLQIEQSVISHQLAMLRDHQLVSATKHGKLSYYKLDDPHILDISGEVLEHADHVVRGKQHGQ
>NZ_LT960781.1|WP_162296395.1|203229_206067_+|WxL-domain-containing-protein
MPTDSKTSSHSEQSVSTQSKSESKSESKTTSSEKSSSETTTQSSSSHRDKSVIQNQSRDTIMPTATIDDGVTGWQPAKQTTIASIDIDKAANKSLNYTFGNSDGTLKFDQGNGGIITNNMPPRMNVFIKDNGKIVESSFKSTSGMGGSYDYSLLTTRSSTAPTIKTTSTSAQGSLTGVQYYQAKDAKGQTILKMVGQYTTIVGRVPSFTLEYLLRPSLEKPSVQQELYIYNATSAAIDGGIFFAKDTSLNGNDGVPVSAQGNNAGMYIADGKYKLFLNMGVEDGPAKFNAMNYHRNGGYNLSDYAMNDYSPANFDGTGIEVKNLKEGATVYSGSDSAYSAKWNWQTFQPDTVYHFRNDLGIATAGLVVPEAAENYKNKTTSDQKNHVQDNITIEMKAHNSGYSSEWKDINVTSKIPDELDIDPSTIKVTLNNGDQVAIDASKYNQTTRMLTVRLLKNLSENEWSSISFDAKINGKASGKTINSSMVAKTESGTGNFDTATANTKIPVEVEPVEIEKKVLNETEKETTYQKATVGHVNDVLDYQVKLTVSSNGADMSNGVLADDLAKEGLKLVPGSVKLTYSDKTVETPADVKQINLKKMTPGQNVVLTYKAKVKEGVVIGTVLKNIVLYSGEQANQGVMNGQADASVTIEKTKNSDVHFSYIDRETGQQITNEVVATGPIDAKISALKATDISDGQDPNKIRPAYIEGYTPVDFTTATDLNAAVYADIKDVDPVIEEKSVTYTFRYEKTRLAITALPSKLNFGKFDDTQSERTFYLPAQIEKPADEKTPYGIEISDYWGIKGWTLSVAQEQQFHGSATIDLKEQVVELSGAQLQFNNATLSTHTEGNKSVSNLQDKVVTKSNFNLVPGAEPLELVEYERKGQYLNQDGDNKGGVSYDIPGYSVHKYQFGDARTADYSIGLHVPETTERYRTEYTSTLKWHLTVAP
>NZ_LT960781.1|WP_101377623.1|202191_202710_+|flavodoxin
MKPLIVYYSRTGNTKAVAKLIHAQVGGDLVALETQEKRPTNYRAEVDLNAREQLQNQLPPLKTNIPDFEQYDRIFIGAPTWNMALPQAVLTFLATYDFTDKTIIPFNTHGGYGAGQMVAQIQAAVGDALVLPILSVAGGQETNGQLLAIEGPTKAAVAKEVTTWLQKSGLLA
>NZ_LT960781.1|WP_076632438.1|201555_202176_+|NAD(P)H-binding-protein
MTNVLIIGAGGQIPAILIPRLQAEPTLKLTLFGSDAANLPYDNVTKVSGDASQLDDLINVMQNQDAIYMNFDNLAITKIVIEAMHETGVKRIIQAGVLSVYGEVAEPFATWNSKMMGGSVAQHRGNEALEASDLDYTYMRMTWLYDAKRTDYVASPKGEPFLGAQISRYAIAQFVVDNLTGKRNDVRASIGLWEPGSENKAKPDFY
>NZ_LT960781.1|WP_076645435.1|217303_219067_+|WxL-domain-containing-protein
MAQYDGMTVPTGDYYWAVATSPTITKLVRNVTADGNNAPFKTATTAQKGDTVEYQVNITQPSGQKLDRGAVFEDVLDSHLKLDSSKGLMIAYATAGSDFDMFQLINFNDQWQFATGQTMEIGQKAQVLIKAIVNDDSAPEIDNLFKLVSGSYGAGTTSNTAIVHVKKPLTLTEAIKNETTDTDWDTKQDVSPGDRVGFKLDYQNTTGATSNQITFNDPLVTNELTYQTGSLKVTYQDGTTETVSDAAQTQFATTGKLTLTKSLANYEAVKLSFSATVNPLVTSGTTLHNKATLTADNVSQPVTSNTVDMNVVQSEHQLTIRYVDLDEDLSQPASAGTQIAAPITVSGKTGTALSTLLPGQQVAPKVIEGYTIYSVSEDPDLKPENWQKAYRDDPQIGDQDRIITYGYKKAMLSIDAPSSWEFGDYNNKPMDRTYYLNHNQGTPQAVTVTDNYGVQNWQLQVSQAKPFVDSEQHELTDAKWAFSNGNVKTLSNTDVGTVTNNSEHFTLASGQSATLMTMTKSGHFQSDSPDTSDPENPYTQVGQGQWAYRFGDEKSADYSIGLNVPATTKRYTGHYRTKLTWSLSVGP
>NZ_LT960781.1|WP_076645437.1|219140_220178_+|DUF916-and-DUF3324-domain-containing-protein
MRLRKWTTGLAVGLFGWLLLASNQPVSAAQEHIDFEVEKVKSNRQVDQENRFFDLGIEPGKKETIQVLVHNFSDKNIKVHSEIDNSLTQQGGGIIYRPTKDGIIKETSHTLMDVAKVHRADRVITLGPNEVKKVSVTITMPSEQTKGMIYGAWHFIEYGQKETDNHSNVSGSYAYNMGIVLRGKPYEIYPELKYQGVNPTVRNGHPALGIQLNNTKPMAIKNAKVKAVVYKNGFFKDKRVYETDSVDVAPNSQWTVPISWAFDRLKPGRYNISISVKGNSYWNQLPMSWHFRKKITINQQQADKINQASVKKPVNKWAYVATASGILMLVSFWFVYRVLKLTRGL
>NZ_LT960781.1|WP_101377627.1|220396_221245_+|WxL-domain-containing-protein
MKFTSTVLTASTLLAILAPATIASAATPKDDAAANGGTKLPMTDTTDAGISFGDTHDNGNSGYLRLQMVPKTLDFGNHAKYDAAHTNFDATGANLGVVGNDTHASYDQQDSNKTETLTTSDANLKAVQGTAWATVVDKQVENPELAAATPKANTAGDWKLTVSADGDGLKAGGHTIADANLVFGNTKYGRTADIYGLTNQDQDNDGYTAAGTTDATYAKSVILNLSTPNEEKVVGTAAKDAGDGANVFGWNPSDIRLALNGSNDVATGEYHAGLTWTLNTTI
>NZ_LT960781.1|WP_076645441.1|221336_221900_+|DUF916-domain-containing-protein
MFKRLNMLWFCLILVDLLTVQTSNPVFAKSEGLAIPAEPKATFMLRPELPKDNLGGKQLGYFNLKLKQGQQRTVFLKVFNPTAQPLTIYGRVKDATTNDNATVDYLGANPIDRQLLKQPGSQLVKVPRATKLQPNETKRLKVTIQAPTKSFKGQKATAINLSTNQLAKHNAVENHYVYAITLILNGR
>NZ_LT960781.1|WP_076645443.1|221954_222389_+|DUF3324-domain-containing-protein
MKQKRAAISVAIANPNPAYLKSATVKVDLQNQRWSLIRYQDQKSNRKIAPNSRFYEDVPLGGKRLVAGVYRMTLTIKTAHQQQIIHKNVAISKGQARYINQNNNQYLKYRNLLLLGGFVMVLMGVVGGYRILKVKHKKRDEHDD
>NZ_LT960781.1|WP_076645445.1|222537_222801_+|hypothetical-protein
MLAKAFAISRPAMSRKLTVLFRNGKIKKLYNLKDEDQRITSLQVTAEGKAIVAALNDEYDAILLPYSKRSDALMAQFIVISNQILKK
>NZ_LT960781.1|WP_101377628.1|222897_224817_+|hypothetical-protein
MDREKGFRKVLLFGLALYVVGFGLGQNVTHSYVTETSSDATLTSQLSSDSESTSSQSSSETLASETPKIAPETKGESTNPVKVMPSLAKTQTPVTQKVARAATTYKIQDLIDQGGVKTTVTWDIYSQSEDDISQGYTGTYYPKVIKFSVLPNNVLQPGDTISFSVLRYTGKLSGQGPVTMASVSLRELGQYDGKSLVLGSEYVPDKAVDASSDLPKSSGGVATLTNETTPDYTAAYAGSTINGTKSSVTVIPATHFNGFQVTNAAVGSDKKGTLTLSGYTKDQTYFQSALDGTPNLKGVPTANYVRIYRIDKESAQNINKVSFDLKTYMPALMPDGQHMAAKAGTTRPMLFIKAPAAVPINNSGSVAADATDDEIIAKTSPQTYGVLHNSDGSMTLYLNYGNLTRPYELPVDTITKGVMNNSWDGTQEGLDYALNRLSNNNYSALATSTYFTMNISFNDPSIENTVQATYKDTLNNTETINQPSSPPSAPTDGQTTIKVHYADQNGKYIKPIETHYGWPDTDKLQITTQYLTIPGYTLDKSNLPKGADPDTGALTLSYPKEAGKVDDILYRFIQNKQKIDVTYVDDTTGKQLATDTMLGVVDENSKYNTQTKLAAYEKQGYQLVSDETDGATLLFSDQD
>NZ_LT960781.1|WP_101377629.1|224826_225816_+|hypothetical-protein
MHLKHAIKAAPDESKQVKRTIHYRYQSNKQAAPDVVDKITFTRHDQIDQVTNQSIGFTKWVSTEGTTTFAKQTSPVIKGYTADQLTVPAVENITQDSADITATVTYTGQAQKATVTYQRSDNQAVIQVDQLTGVSGQISDYRTDATLAALADKGYTVADNPYPSDGLVFDDDVAVDQNVTVLLNYNPYYNRVYFKSVPSEMDFGQHTLASTTESYQPTVNQALSIQDERALGSKWTLKAALVQPFTGDTQKAPLEGDLTYQRANQLPTMITAQSTIIATTTTTSHDPVDISGQWQNQLGPQLVVPVGGALIDQYAAQVEWTLEDGVANE
>NZ_LT960781.1|WP_101377630.1|225946_226249_+|LPXTG-cell-wall-anchor-domain-containing-protein
MRWLKNKSKFVVLMLIIGSGLIVVNPTHTSANAQTATKSVARVGFYETGQPHKQAPIQTETKQQARLPQTGTSSVGLSTIVGIVLLIGSLGLFKQKRGNF
>NZ_LT960781.1|WP_101377631.1|226250_226454_+|hypothetical-protein
MKKFMMSTLLLSGMLSISMGQVHAADTDSHDTTGKVGFKAPDTGGLTMTNTDALNIDFGSNPISADG

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Crispr_ID: NZ_LT960781_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT960781_2

1733455-1733547

Orphan

Consensus_repeat	Method
ACTTGATTCTTGATTTGATGATTCACTGCTTGA	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NZ_LT960781_2

>merge|NZ_LT960781|2|1733455-1733547|CRISPRCasFinder
ACTTGATTCTTGACTTGATGACTCACTACTTGATTCACTGTTTGAGTCACTTGATTCTTGATTTGATGATTCACTGCTTGATTCGCTGTTTGA

>NZ_LT960781|2|2|1733455-1733547|CRISPRCasFinder
ACTTGATTCTTGACTTGATGACTCACTACTTGA	TTCACTGTTTGAGTCACTTGATTCTTG
ATTTGATGATTCACTGCTTGATTCGCTGTTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT960781.1\|WP_101378030.1\|1726531_1728163_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|287142
NZ_LT960781.1\|WP_101378029.1\|1724700_1725084_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT960781.1\|WP_101378040.1\|1741974_1742559_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NZ_LT960781.1\|WP_101378039.1\|1740089_1741550_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_LT960781.1\|WP_101378031.1\|1730270_1731191_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LT960781.1\|WP_101378036.1\|1736696_1737587_-\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NZ_LT960781.1\|WP_101378037.1\|1737583_1738600_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226359
NZ_LT960781.1\|WP_056947582.1\|1750150_1751137_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|129820
NZ_LT960781.1\|WP_101378035.1\|1735879_1736704_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NZ_LT960781.1\|WP_101378028.1\|1721484_1722930_-\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|274774
NZ_LT960781.1\|WP_056947580.1\|1751220_1752099_-\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NZ_LT960781.1\|WP_101378032.1\|1732383_1733061_-\|class-A-sortase	unknown	unknown	gnl\|CDD\|320680
NZ_LT960781.1\|WP_039099505.1\|1728269_1728971_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_LT960781.1\|WP_101378038.1\|1738751_1739714_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NZ_LT960781.1\|WP_089535182.1\|1748557_1750048_-\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NZ_LT960781.1\|WP_094365844.1\|1728989_1730129_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|238434
NZ_LT960781.1\|WP_076632278.1\|1731456_1732263_-\|pyrroline-5-carboxylate-reductase	unknown	unknown	gnl\|CDD\|237008
NZ_LT960781.1\|WP_089541951.1\|1725158_1726211_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LT960781.1\|WP_157826354.1\|1719889_1721092_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378270
NZ_LT960781.1\|WP_101378034.1\|1734605_1735874_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270451

Protein	Function_ID	Function_description	E-value
NZ_LT960781.1\|WP_101378030.1\|1726531_1728163_-\|hypothetical-protein	gnl\|CDD\|287142	pfam10131, PTPS_related, 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein. This domain is found in various bacterial hypothetical membrane proteins, as well as in tetratricopeptide TPR_2 repeat protein. The exact function of the domain has not, as yet, been established.	4.01102e-05
NZ_LT960781.1\|WP_101378040.1\|1741974_1742559_+\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	3.72876e-31
NZ_LT960781.1\|WP_101378039.1\|1740089_1741550_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	3.60004e-147
NZ_LT960781.1\|WP_101378031.1\|1730270_1731191_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.93296e-55
NZ_LT960781.1\|WP_101378036.1\|1736696_1737587_-\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.63306e-75
NZ_LT960781.1\|WP_101378037.1\|1737583_1738600_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	2.1098e-116
NZ_LT960781.1\|WP_056947582.1\|1750150_1751137_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|129820	TIGR00737, Probable_tRNA-dihydrouridine_synthase, putative TIM-barrel protein, nifR3 family. This model represents one branch of COG0042 (Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family). This branch includes NifR3 itself, from Rhodobacter capsulatus. It excludes a broadly distributed but more sparsely populated subfamily that contains sll0926 from Synechocystis PCC6803, HI0634 from Haemophilus influenzae, and BB0225 from Borrelia burgdorferi. It also excludes a shorter and more distant archaeal subfamily.The function of nifR3, a member of this family, is unknown, but it is found in an operon with nitrogen-sensing two component regulators in Rhodobacter capsulatus.Members of this family show a distant relationship to alpha/beta (TIM) barrel enzymes such as dihydroorotate dehydrogenase and glycolate oxidase. [Unknown function, General].	5.73323e-139
NZ_LT960781.1\|WP_101378035.1\|1735879_1736704_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	6.28965e-86
NZ_LT960781.1\|WP_101378028.1\|1721484_1722930_-\|glycosyltransferase-family-39-protein	gnl\|CDD\|274774	TIGR03766, hypothetical_protein_lp_2141, conserved hypothetical integral membrane protein. Models TIGR03110, TIGR03111, and TIGR03112 describe a three-gene system found in several Gram-positive bacteria, where TIGR03110 (XrtG) is distantly related to a putative transpeptidase, exosortase (TIGR02602). This model describes a small clade that correlates by both gene clustering and phyletic pattern, although imperfectly, to the three gene system. Both this narrow clade, and the larger set of full-length homologous integral membrane proteins, have an especially well-conserved region near the C-terminus with an invariant tyrosine. The function is unknown.	4.51413e-18
NZ_LT960781.1\|WP_056947580.1\|1751220_1752099_-\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	6.51489e-152
NZ_LT960781.1\|WP_101378032.1\|1732383_1733061_-\|class-A-sortase	gnl\|CDD\|320680	cd06165, Sortase_A, Sortase domain found in class A sortases. Class A sortases are membrane-bound cysteine transpeptidases distributed in Gram-positive bacteria (mainly present in Firmicutes). They perform a housekeeping role in the cell as members of this group are capable of anchoring a large number of functionally distinct surface proteins containing a cell wall sorting signal to an amino group located on the bacterial cell wall. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is cleaved at a conserved cell wall-sorting signal (Class A sortases recognize a canonical LPXTG motif, X can be any amino acid), and covalently linked to peptidoglycan for display on the bacterial surface. The prototypical sortase A protein from Staphylococcus aureus (named Sa-SrtA) cleaves the amide bond between threonine and glycine residues of the canonical LPXTG motif in a wide range of protein substrates with diverse functions that can promote bacterial adhesion, nutrient acquisition, host cell invasion, and immune evasion. Next, it catalyzes a transpeptidation reaction by which the proteins are covalently linked to the peptidoglycan precursor lipid II. SrtA is therefore affects the ability of a pathogen to establish successful infection. SrtA contains an N-terminal hydrophobic segment, a linker region and an extra-cellular C-terminal catalytic domain. The hydrophobic segment functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring. The catalytic domain contains the catalytic TLXTC signature sequence where X is usually a valine, isoleucine or a threonine. The gene encoding SrtA is generally not located in the same gene cluster as its substrates while the gene encoding SrtB is usually clustered in the same locus as its substrate.	1.71438e-48
NZ_LT960781.1\|WP_039099505.1\|1728269_1728971_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.26434e-84
NZ_LT960781.1\|WP_101378038.1\|1738751_1739714_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	5.73209e-14
NZ_LT960781.1\|WP_089535182.1\|1748557_1750048_-\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NZ_LT960781.1\|WP_094365844.1\|1728989_1730129_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	1.58284e-153
NZ_LT960781.1\|WP_076632278.1\|1731456_1732263_-\|pyrroline-5-carboxylate-reductase	gnl\|CDD\|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	3.89266e-84
NZ_LT960781.1\|WP_089541951.1\|1725158_1726211_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.84192e-68
NZ_LT960781.1\|WP_157826354.1\|1719889_1721092_-\|hypothetical-protein	gnl\|CDD\|378270	pfam09843, DUF2070, Predicted membrane protein (DUF2070). This is a family of Archaeal 7-TM proteins. There are 6 closely assembled TM-regions at the N-terminus followed by a long intracellular, from residues 220-590, highly conserved region, of unknown function, terminating with one more TM-region. The short 25 residue section between TMs 5 and 6 might lie on the outer surface of the membrane and be acting as a receptor (from TMHMM).	0.00916452
NZ_LT960781.1\|WP_101378034.1\|1734605_1735874_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270451	cd14748, PBP2_UgpB, The periplasmic-binding component of ABC transport system specific for sn-glycerol-3-phosphate; possesses type 2 periplasmic binding fold. This group includes the periplasmic component of an ABC transport system specific for sn-glycerol-3-phosphate (G3P) and closely related proteins from archaea and bacteria. Under phophate starvation conditions, Escherichia coli can utilize G3P as phosphate source when exclusively imported by an ATP-binding cassette (ABC) transporter composed of the periplasmic binding protein, UgpB, the transmembrane subunits, UgpA and UgpE, and a homodimer of the nucleotide binding subunit, UgpC. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.31474e-83

>NZ_LT960781.1|WP_101378032.1|1732383_1733061_-|class-A-sortase
MKGQQKCPAVKWVRWLFMASLCLFLGLIGVQKYQHDQLTQNIDRARIVKVRPVQTKKMADDNAPQPTYWDEDTRGITVGKLAIPSVGIKLPIIKGIGQTNGHDNMLKAAVTNKQGQTMGKRNYVLSSHDIAQENVLFSPLSQTKVGAAIYLTDTKQVYTYRVISRKTVKANQVAILDDVRQKHLVTLYTCDPDGEIVNGQTYERTVVVGELVKTSQASVKNLARF
>NZ_LT960781.1|WP_076632278.1|1731456_1732263_-|pyrroline-5-carboxylate-reductase
MKIGFIGVGNMAQAIIKGLVKADQIATTDILVHGAHPANYEAFAAEQHITPVADNIAVVAQADIVFLAVKPYIVPLILEETGAAFKEKQPLMVSMAAGLSLAKLSQQVDADNLPILRIMPNVNVANRAGITAVVGNAQVSADQLKSVKDVLSQLGGVVEIGEKDFTTFSALAGSSPAFVYLFIDSMARAGVKHGLTKKAATEIAAQAVLGSAQNVLLSDDSPWDLIDKVSSPGGTTVAGLLAMEEAGLMSAVVKGIDATIEKDLESQK
>NZ_LT960781.1|WP_101378031.1|1730270_1731191_+|Gfo/Idh/MocA-family-oxidoreductase
MLNIGVIGLGNIAQKAYLPVMAQLQDQVNWVLCSRQPAKLAQLQDQYHFSNGCLSFEDLLAKSLDAVFIHTPTNTHYTLVKQALSHGLNVFVDKPLSENPLEVAELYKLAAQQGLLLTVGFNRRFVPQLQKLKSIPNKQLINVTKTRVDTRQPAAFAIYDLMIHTIDTALYLANDVGLNDNVQPYCKQDANQQLQVAQLTIETASQLITATLNMQGGTNQEIASLQSPHGLFSVDNLTQYTAKTATDNRQQQPADWEPTLVSRGFDPMIKAFIAALQTNGENPVSPASSLLTHQLCHTMCRQAQRC
>NZ_LT960781.1|WP_094365844.1|1728989_1730129_-|N-acetylglucosamine-6-phosphate-deacetylase
MTIKVLKHAVIYTGDDVIEDGYIRFDKQILAVGPMFDYKAQAGEEIQDMKGQTIIPGFIDVHCHGGYGFDAMDGDANQIDEMATKMMQNEGVTTLFATTMTQSNENIANAMRGVKDAAEKNPLIQGVHLEGPFIAPIFKGAQPEQFIKDPDVDLLDEWNKLSGNRVRLITYAPEDPGSKAFEDYCLAHNIVPSVGHSNATREQMIESKATHVTHLYNAQREFKHREPGVTGHAMLEDNMYAELIADGFHIVPDMIKLAYEQKGAERIDLVTDSMRAKGIAEGESELGGQKVIVKDKQARLEDGTLAGSVLTYIDAFKNIQTFTGCDKFEAVMMSSVNQAEEFGLTQKGKLEVGRDADLNVLDQQQNLVATYSFGQGYQH
>NZ_LT960781.1|WP_039099505.1|1728269_1728971_-|GntR-family-transcriptional-regulator
MESPVYIQIHNQLKKDIEAGKWSIGDRIPSERELALNFEVSRMTLRQAVQTLVDEGILERRIGAGTYVANQKVQEKMSGVTSFTDLMTAQGKQPSSKTISFHIANPSLSEAEKLQLKDGEQVLRMERIRYADNVPICFEVATVPQSLVADFSKAEITSSFYKALAEKGGYEMGGAQQTVSAQLASERIAEYLDIKRNGPILKLRQVSFLSNGEPFEYVRTQYVGERFEFYLER
>NZ_LT960781.1|WP_101378030.1|1726531_1728163_-|hypothetical-protein
MVKAVKKNNELIGIIILFVVLSIFYTYLMAPQHTLIARDSLDGYFHLNRALSLRHIWYSPINFNDWGGVGNATALFYPWLTIYPMHLLTVIFGPVSGFLLSLTLVTFLTLVSSYISAIKFSGEQLFGILFALIYTFSFIRNTSVMYRWGVGEYIAYIFIPPLFLCFYNLLRQQPKQLRWVIIFFSLILYSHVLSIVTTSFGLCCVLFSFLVQKKFNRTYLIYITKKFLLFVAGCLTMTMAYWGPMLEQKRFQTINMPQPFDFKQVTKSLEQLIRYSFSLDFRTYTIGIVFLSTVVIILMTVWLEKTLYRTIGIISLVILIMTTTVIPWWALQQTPVSIIQYPGRFLNIFCFFVALYLAHLCSVGAKYMGKFWRLVPSLVIIILMITLISGARILWHAQTSVPPELSVIRNNDLNKIKRFRQKDYYPKAALLNTEHLIVKKEYNGGQIKPMRIISKDHFKMTVKSTENSKIKLPILYYKGIITRINNQNTVPDRTKFGTVSLNLKKGVNQIDVSYRYTVVAKISFLISFLTVFCLFSNQFIIEE
>NZ_LT960781.1|WP_089541951.1|1725158_1726211_-|IS30-family-transposase
MQKQDTTHRQKGQHLTSLERGKVAGFRQAGKSNRWIAAEIGVCPQTINNEIKRGTVDQVKKSNGKRVYHRQYLPEAAQARYETARLSCHRPDKFASVQVFLAWYVQRAKQDKWSPDASIGYAKRHKLFTPEELVCASTLYQYIDDQRLEIRNIDLLEKTKRKTSHQHHTKAKRLAGRSIEERPKVVERRRQFGHWEMDTIVGKRNGKESVILTLIERKTRCQLLRLIEGRDADSVSYALRGIKREWGACIKTITADNGPEFTALNTAFAGTETEIFYAHPYTSCDRGTNEAHNRMIRQDFPKGMSLDDISPSQVQATQDRLNQLPRKQQGYCTPQQNFEAEARRVRRMAQ
>NZ_LT960781.1|WP_101378029.1|1724700_1725084_-|hypothetical-protein
MQFTSSKKSVTVQKNEKSSTKKSATSSSAQSTTSGKNTDGKFQYSILGTWYSNDTKVTYNEDGTIVQVSDASGMTNRGTYQILKETKDSLIIEQILKVKNAGKDRQQETFKFTDKNHFNDGLVDWKK
>NZ_LT960781.1|WP_101378028.1|1721484_1722930_-|glycosyltransferase-family-39-protein
MQKFMNGFVKGAYTVLLVSIFAFITYYSISNLVTGNYLSNSKLMIVAIAFYILIILALVLLTKITSKKIFFMIVTGMAILVRIGWLIKVPTAPSSDFQMMHHAAILATQGDLSFLKESYFQSWPYQLGFVYFQALIIKIFGQNVLILQIINILLNCGIAFVGYKIINLHFKEITGRIVYTLLLFYPAYIYMTGVLTNQFLATFLIYLAIYLYLKHDQLWVKATAGVLLALGNMMRPLGILLIIALVCFEITKWLTGSEKYFKITRKSTTSVLAYFLMLFLVNSALQVTHLSEYPLENRNPTWKFVLGLNDETVGSYSATDLSLMNRYPLGAKRDKLGKEIIKERIQDKPKLVNLMFNKSKKMWTARDDALMWGMADNVKLSLKIKNWLNAVQFLFYIFIVANALLAVFKWRETWTDGYLLKLMIIGYFMVHLLIEIQSRYRFFIVPAFIMLAAVGWVTVYEKIHSRQANDKKTLKEDIVIR
>NZ_LT960781.1|WP_157826354.1|1719889_1721092_-|hypothetical-protein
MSTELFAQVLGWNAGFFNYMASLVYPLIIINLVKYHYSDWQASKYLRYSILIAVLSIISCFFVEHVTLLNLAVATILMGYMLYQKKKNYLVIANFIGTYIGGILMFSNKAYLNILLHHDSYRETSFSLTKVYHIISQQMDFYLLIDNPIITVLLAVILGYLIIKNLQKRSGNKLGTVVSYLELSILIAFIEYHYILFNTFLKDFGHRYLVSCLLSILFLLVIVIEMAKLSLETHNIEYIALIAAAIVLIVPFFVVTPFGPRGAFASYFCLCLLVVALCNELNAVKFSLPIIRIMMVMVVIFYAGLATRIGHASRIKNDFITYQEKHNTPKDYRLYLEVPYNQYYWAVHPQATDSSYRGYYKIKTIGGKLVPYAKWRLIEKNTNSNAEMFSQVLKVDSQNK
>NZ_LT960781.1|WP_101378034.1|1734605_1735874_-|ABC-transporter-substrate-binding-protein
MKKKLVVSLFLIFLLGMSSTKVAAKSNAEPVKITFWHAMNGPYKAALDNIITDFNESHPEYQVEGTSQGSYSALQQKLTAAAKAKTMPTIAQTVYTSVPDFQSAGMLQQLDPYMNHGKNALTKKDRKDIYPVFMDSSKYQSHYYSMPFSKSLRVMYVNQDLLKKYHLKQPTSWEAMQKISKKLKKHDIYTVGLDKSFDIEYDMLIHQLGVRQITKKGKVNIDSKASLQAAHVITDMLKAGTAKTAGADKYFTNGFIQGKALLYIGSSAGMTQIQQQAPKDFHWTAVPVPSYHGKQTTEVAGNDLVMLSGAKKQQQKGAWAFMKYLTSRQVTAKWAAETNYVPVRRSAVKEKVYQNYLKKNPEAKAAAESLPNAFTGVAFKGSNEYQLEMWNAVDSMVTKGTSPEKAFKKLAKQAKTIIADHQ
>NZ_LT960781.1|WP_101378035.1|1735879_1736704_-|carbohydrate-ABC-transporter-permease
MTKQNGYRLLGFVILCLGAVIMVLPLLWMLTTALKTSFEAQQAPPVLFPHHWQWQNFKTAWQAAPFTRYLWNSLLVAFLVTISQLVISTLAAYAFARLQFYGKRVLFILCLTTLLIPGEMLLIPNFVTITQLHWFDTYRGLVLPPLANFFSVLLLKQAFESIPTAIYQAARLDGAGDLRCLLSVGLPLVRPTLVTVGLLQIIASWNAFMWPLVATNSEQYRTLPVGLQSFTAEAGTQYQLLMAASTLAMIPLILVYLSGQRYLIQGLSRTGLKG
>NZ_LT960781.1|WP_101378036.1|1736696_1737587_-|sugar-ABC-transporter-permease
MKQQPTLRGSLKAYLYLLPLLTALGLFTFYPMVKTLLMSLYTRYDFLTDHVSQIGWANFQFIWHDPDFHLALKNTVVFALWVVPLATILAMGCALLLARNPWFNRLLRTIYFLPFVTSTVAISLVWNWLFQTDYGLINAMRVWLGQTRIAWLSDPHYAMVALISLVLWKSLGVNILVMLVGISRIDQRLYQVAILDEASPHQRFWHLTLPLLKPTIALVILMTTIASFKLFNEVFVLFQGSPGPGKSTLTVVFYLYDKFYVAYQYGIAAAASVVLFVILLTLTALQWWVRQGAWHD
>NZ_LT960781.1|WP_101378037.1|1737583_1738600_-|ABC-transporter-ATP-binding-protein
MGIQFDAVSMRYGQQTVLQQLNFEIPSGVLTTILGPSGCGKSTLLMLIAGLLKPSTGTIKLPEKTTVGMVFQDYALYPHLTVQENIAFPLKMQHIRKKERQQRVQALATQLQITDCLVKKPHALSGGQQQRVAIARALAKQPGILLLDEPLSNLDARLRLEMRDFLKQLQTQLQIIMVIVTHDQDEALHMGQSMLVLNDGVVQQIGRPNQIYQKPQNLFVARFIGNPMINTLSLAALAGALNLTATQQAATATIAIRPESIIAPAEYPSEQLLGTFKGRVDNQETFGSETRTVLQIGSEKVISTAISAGKAVDQWGLLKAGVLGYDAAGQLLWAGDEQ
>NZ_LT960781.1|WP_101378038.1|1738751_1739714_+|WYL-domain-containing-protein
MKSTERITSILIALFEKEKPTVTDLTERYETTERTIQRDLATIREMLIEQRSAVTLHKDHRGRYYIQNPARIPIEEALALSKIVLSSRAFNKTELNQILTHLRSQLTAESQNILDRIIGSENIQYHELQHHLAPHDASILTRLNQFTHYVEEAQVLHFGYTRADEVHEEQDGLPVAISFNLFYFYVWLYTERKGRPYSIYRLDRFDNVKPLKRKITIPYRDRWDDGQFSVKSFQMFTGRDVTFRFEFWGLPEVPLDRLAHAKIIKPKAFPEDSVIVEASALDNGVMMWLLGEGASVKVLSPPSFVARFKAEVAKMQAHYQ
>NZ_LT960781.1|WP_101378039.1|1740089_1741550_-|peptide-MFS-transporter
MEEKHEKTFFGQPHGLSTLFFTEMWERFSYYGMRAILLFYMYFALDKGGLGFDKATAMSVMAIYGSMVYLASVVGGWLSDRIWGSFKTVFIGGFFIMLGHIVLAVPMGATALFISIGLIVAGTGLLKPNVSEMVGGLYSEDDRRRDAGFSMFVFGINLGSFVAPWVVGTIGQQVNFHLGFSLAAVGMFFGLIQYYRGRSQFSKENSKPNDPIASDELRGIIIKVVIGLVVIALGITALQLTNNLNIDNIVLIISIVAIALPIIYFYNMLSSKKITKKERSRVLAYIPLFIAAAVFWGIEESGSVVLALFAEDRTILHIGGWKLAASNFQSLNPLFIMLLTPLFVWLWSTWKKQPSAPGKFAVGLIFAGLSYMFMALPGLLHGTAVRVSPFWLIGSWLIVEIAEMLISPIGLSITTKLAPKAFRSQMMSMWFLADAAGQAVNAQLVRLYSPQTEIKYFLGIGIVSAIFGIVLIFFVKPIHKLMEGVD
>NZ_LT960781.1|WP_101378040.1|1741974_1742559_+|NUDIX-hydrolase
MTQLKLVALKKLLADRWLNYYEATYQNPKQEEINYHFVSREANLTTDNLKHPVTASAVTMFCLNHDHSQVLLLRQFRLPLNDYVYGNSAGLIEPGETVEQAIERELVEETGYQGVHIDQIFSPSYSTPGITDGAITLAICTIDQHPSQETALESAEELTSIWVDKKRAAEILASGKISGRTQLLLWQWVNDRLN
>NZ_LT960781.1|WP_089535182.1|1748557_1750048_-|lysine--tRNA-ligase
MNDQLKVRREKMQFLKDEGIDPFGSRFERTHLAAALHEEFEAIEKDDLDVKNQEVTIAGRMMSKRGKGKVGFADIRDRSGKIQIYVRKDEVGEDNYKIFKKADLGDHLGITGQIMKTDMGELTVKATHLTFLSKALRPLPDKYHGLTNVEQIYRQRYLDLIANPESMDRFTKRSKIISAVREYLDTHDFTEVETPVLHGQAGGASARPFITHHNALDINLYLRIALELHLKRLIVGGMERVYEIGRVFRNEGIDTKHNPEFTMLETYAAYFDYKDVMDETEGIIRFAAHKVLGTGQISYQGQAIDLDGDFARVHMVDAIKAETGVDFWQPMTVEAARELADQHHVKYEEYWQVGHIINAFFEEFVEETLVQPTFIYGHPVEISPLAKKNAEDDRFTDRWELFMHGNEYANAFTELNDPIDQRERFEAQAKERENGNDEAEGIDEDYVEALEYGMPPTGGLGIGIDRLVMLLTDAASIRDVLLFPTMRPDKQENEEI
>NZ_LT960781.1|WP_056947582.1|1750150_1751137_-|tRNA-dihydrouridine-synthase-DusB
MTWQIGDVTIPNQVVVAPMAGITNAAFRVTAKEFGAGLVVCEMISDRGIMHNNQKTMGMMFVDPNEHPVSIQIFGGSKDTLVEAAKFVDQHTQADIIDINMGCPVNKVVKTDAGARWLLDPNKVYEMVSYVTDAVKKPVTVKMRTGWDEDHIFAVQNALAAERAGASALAMHGRTRKQMYTGKADWDILKQVKAELKIPFMGNGDVRTPQDAKRMLDEVGADAVMIGRAALGNPWILRQVETYLRSGELIAEPTPREKIATAKLQLHRLVELKGENVACREFRQQAAYYLKGIPRAAKTKAAVNEVETEQAVGDILDRFVEETEARMA
>NZ_LT960781.1|WP_056947580.1|1751220_1752099_-|Hsp33-family-molecular-chaperone-HslO
MKDYLVKQVSEDGQLRAYAVNATQVITEAQEKHDTWPTSSAAFGRTIVGTLLLSAAGLKGDTKMTVKVEGDGPVGKIVVDGNAQGTVKGYVTNPHVNLPSNEKNKIDVKAGVGTTGTLSVTKDLGLKEPFTGQVPLVSGELGEDFTYYLAKSEQTPSAVGVSVFVNEDSTIGVAGGFMIQILPGADDRLIDILEARLQEMPLVSELLQQGMTPEEIITEIVGELPMKTLEELPVKYECDCSKERFAKALSSIAPQDLKQLIEEDHGAEATCRFCGKQYQFSEADLKAILAEQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LT960781_2	2.1\|1733488\|27\|NZ_LT960781\|CRISPRCasFinder	1733488-1733514	27	MT857002	Salmonella phage pSal-SNUABM-02, complete genome	79666-79692	6	0.778
NZ_LT960781_2	2.1\|1733488\|27\|NZ_LT960781\|CRISPRCasFinder	1733488-1733514	27	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	695076-695102	7	0.741

1. spacer 2.1|1733488|27|NZ_LT960781|CRISPRCasFinder matches to MT857002 (Salmonella phage pSal-SNUABM-02, complete genome) position: , mismatch: 6, identity: 0.778

ttcactgtttgagtcacttgattcttg	CRISPR spacer
gtcactgtttgagtcacttcagtcact	Protospacer
 ****************** * ** .

2. spacer 2.1|1733488|27|NZ_LT960781|CRISPRCasFinder matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 7, identity: 0.741

ttcactgtttgagtcacttgattcttg	CRISPR spacer
agaactgtttgagtcagttgattcact	Protospacer
   ************* ******* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

569580 : 624732

Streptococcus_phage(25.0%)

transposase,holin,bacteriocin,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025016320.1\|569580_569955_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_099712933.1\|570092_571034_+	HPr kinase/phosphorylase	NA	NA	NA	NA
WP_162296404.1\|571161_571986_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
WP_085391646.1\|572003_573026_+	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_025016317.1\|573142_573544_+	hypothetical protein	NA	NA	NA	NA
WP_100970141.1\|573660_574581_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	3.4e-85	51.1
WP_101377674.1\|574736_576461_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.1e-181	55.0
WP_016264744.1\|576585_577218_+	HD domain-containing protein	NA	NA	NA	NA
WP_016264745.1\|577425_579429_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_016264746.1\|579438_582291_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.3e-305	54.9
WP_016264747.1\|582412_582949_+	DUF308 domain-containing protein	NA	NA	NA	NA
WP_101377675.1\|583074_583959_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.6e-07	27.2
WP_016264749.1\|583955_584990_+	YvcK family protein	A1IMD5	Streptococcus_phage	9.0e-95	54.8
WP_011374236.1\|584992_585937_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.3e-52	39.0
WP_035146456.1\|586028_586484_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_101377676.1\|586598_587123_-	DsbA family protein	NA	NA	NA	NA
WP_025016311.1\|587347_587932_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.5e-51	53.4
WP_157826325.1\|588475_589057_-	glycoside hydrolase family 73 protein	A0A249Y0X5	Enterococcus_phage	1.3e-21	40.3
WP_101377678.1\|589271_590231_+	nucleoside hydrolase	NA	NA	NA	NA
WP_101377679.1\|590420_592382_+	hypothetical protein	NA	NA	NA	NA
WP_016264756.1\|593298_593943_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_025016307.1\|594042_594423_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_016264758.1\|594419_595331_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.6e-10	31.9
WP_016264760.1\|597433_598180_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_035144627.1\|598211_598613_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_101377680.1\|598692_599157_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_157826326.1\|599173_599437_+	hypothetical protein	NA	NA	NA	NA
WP_016264763.1\|599519_600086_+	hypothetical protein	NA	NA	NA	NA
WP_016264764.1\|600107_601226_-	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	8.4e-14	28.1
WP_035146470.1\|601336_601978_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_101377682.1\|602116_602989_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	7.5e-18	28.3
WP_101377683.1\|602992_603736_+	ABC transporter permease	NA	NA	NA	NA
WP_076647158.1\|603735_604863_+	sensor histidine kinase	NA	NA	NA	NA
WP_076647160.1\|604855_605461_+	response regulator transcription factor	NA	NA	NA	NA
WP_076647163.1\|605530_605857_+	hypothetical protein	NA	NA	NA	NA
WP_076647166.1\|605980_607621_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011374258.1\|607700_608108_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_011374259.1\|608173_608470_-	hypothetical protein	NA	NA	NA	NA
WP_011374260.1\|608675_609038_+	hypothetical protein	NA	NA	NA	NA
WP_101377684.1\|609974_610841_+	ABC transporter permease	NA	NA	NA	NA
WP_011374263.1\|610867_611320_+	LytTR family transcriptional regulator	NA	NA	NA	NA
WP_011374264.1\|611325_611733_+	DUF3021 domain-containing protein	NA	NA	NA	NA
WP_101377685.1\|611790_612138_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_101377686.1\|612391_612646_+	hypothetical protein	NA	NA	NA	NA
WP_157826327.1\|613559_614261_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_157826328.1\|614836_615628_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_035146503.1\|615629_616376_+	response regulator transcription factor	NA	NA	NA	NA
WP_101377689.1\|616780_617116_+	hypothetical protein	NA	NA	NA	NA
WP_101377690.1\|617214_617397_+	hypothetical protein	NA	NA	NA	NA
WP_101377691.1\|617538_617871_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_101377692.1\|617889_618177_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_056947918.1\|618201_618381_+	hypothetical protein	NA	NA	NA	NA
WP_101377693.1\|618412_618649_+	hypothetical protein	NA	NA	NA	NA
WP_035146515.1\|618721_619045_-	hypothetical protein	NA	NA	NA	NA
WP_101377694.1\|619128_619413_+	hypothetical protein	NA	NA	NA	NA
WP_011374281.1\|619582_620623_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_011374282.1\|620767_621400_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_101378099.1\|621386_621809_-	hypothetical protein	NA	NA	NA	NA
WP_101377695.1\|621980_623333_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_101377696.1\|623811_624732_-\|transposase	IS30-like element ISLsa1 family transposase	Q9MBM9	Staphylococcus_prophage	5.4e-51	38.2

DBSCAN-SWA_2

633699 : 720354

Lactobacillus_phage(29.55%)

holin,protease,integrase,tRNA,capsid,terminase,portal,head,tail

attL 649891:649908|attR 688460:688477

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101377703.1\|633699_634857_-\|integrase	site-specific integrase	J7KBT5	Streptococcus_phage	1.4e-59	38.5
WP_101377704.1\|634908_635652_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085391661.1\|635806_636028_+	hypothetical protein	NA	NA	NA	NA
WP_101377705.1\|636105_636717_+	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	1.4e-39	46.2
WP_085391663.1\|636729_637002_+	hypothetical protein	NA	NA	NA	NA
WP_061827189.1\|637200_637398_+	hypothetical protein	NA	NA	NA	NA
WP_101377706.1\|637537_637786_+	hypothetical protein	NA	NA	NA	NA
WP_101377707.1\|638752_640249_+	DNA primase	A0A286QRQ7	Streptococcus_phage	6.1e-68	34.1
WP_101377708.1\|641131_642151_+	aldehyde reductase	M1NML0	Moumouvirus	4.8e-08	26.5
WP_101377710.1\|642644_644021_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_099960426.1\|644964_645084_+	DUF2292 domain-containing protein	NA	NA	NA	NA
WP_101377711.1\|645185_645608_+	transcriptional regulator	NA	NA	NA	NA
WP_101377713.1\|646095_647334_+	topoisomerase IV	NA	NA	NA	NA
WP_101377714.1\|647539_648277_+	HNH endonuclease	NA	NA	NA	NA
649891:649908	attL	NA	NA	NA	NA
WP_101377715.1\|650073_651186_-\|integrase	site-specific integrase	B4XYR4	Lactobacillus_phage	4.0e-64	37.3
WP_099960213.1\|651381_652347_-	hypothetical protein	E3W8I2	Leuconostoc_phage	1.2e-27	63.5
WP_101377716.1\|652448_652904_-	toxin	A0A2H4JE34	uncultured_Caudovirales_phage	2.4e-15	35.4
WP_099960215.1\|652922_653264_-	helix-turn-helix transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	3.1e-20	49.0
WP_099960216.1\|653422_653650_+	helix-turn-helix domain-containing protein	A0A2H4PQQ0	Staphylococcus_phage	2.8e-09	47.7
WP_101377717.1\|653663_653975_+	DUF771 domain-containing protein	NA	NA	NA	NA
WP_157771196.1\|653971_654130_+	hypothetical protein	NA	NA	NA	NA
WP_101377718.1\|654208_654409_+	hypothetical protein	NA	NA	NA	NA
WP_089535115.1\|654493_654979_+	siphovirus Gp157 family protein	A0A2H4JBT9	uncultured_Caudovirales_phage	4.2e-10	32.5
WP_101377719.1\|654983_655724_+	AAA family ATPase	Q6J1V8	Lactobacillus_phage	1.1e-67	58.3
WP_101377720.1\|655656_657012_+	DEAD/DEAH box helicase	Q9T0Y3	Lactobacillus_phage	1.1e-153	59.7
WP_101377721.1\|657014_657572_+	DUF669 domain-containing protein	Q9T0Y2	Lactobacillus_phage	1.4e-54	57.7
WP_101377722.1\|657590_659885_+	DNA primase	Q9T0Y1	Lactobacillus_phage	1.8e-281	60.6
WP_162296398.1\|660172_660679_+	helix-turn-helix domain-containing protein	A0A1B0YA93	Lactobacillus_phage	1.0e-27	59.4
WP_101377724.1\|660684_660870_+	hypothetical protein	NA	NA	NA	NA
WP_157826329.1\|660986_661163_+	hypothetical protein	NA	NA	NA	NA
WP_101377725.1\|661155_661431_+	hypothetical protein	D2J038	Enterococcus_phage	8.7e-05	36.6
WP_101377726.1\|661420_661819_+	hypothetical protein	NA	NA	NA	NA
WP_035147703.1\|661811_662063_+	hypothetical protein	NA	NA	NA	NA
WP_101378100.1\|662323_662779_+	class I SAM-dependent methyltransferase	A8ATY8	Listeria_phage	2.9e-58	67.3
WP_101377728.1\|662775_663924_+	DNA cytosine methyltransferase	A0A2H4PBE1	Lactobacillus_phage	2.1e-108	53.4
WP_101377729.1\|663997_664252_+	hypothetical protein	A0A291I9M4	Lactobacillus_phage	4.8e-18	58.3
WP_101377730.1\|664248_664581_+	hypothetical protein	A0A2K9V545	Lactobacillus_phage	9.7e-27	61.2
WP_157826330.1\|664609_664759_+	hypothetical protein	NA	NA	NA	NA
WP_101377731.1\|664927_665344_+	transcriptional regulator	E9LUP5	Lactobacillus_phage	2.5e-35	56.1
WP_101377732.1\|666197_666602_+	hypothetical protein	NA	NA	NA	NA
WP_101377733.1\|666605_666851_+	hypothetical protein	NA	NA	NA	NA
WP_099765596.1\|666970_667336_+	HNH endonuclease	A0A1Q1PW15	Staphylococcus_phage	1.3e-16	41.4
WP_101377734.1\|667459_667921_+\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	7.0e-23	36.6
WP_101377735.1\|667913_669623_+\|terminase	terminase large subunit	A0A249XUH4	Enterococcus_phage	1.3e-119	40.0
WP_101377736.1\|669804_670995_+\|portal	phage portal protein	A0A2H4JA65	uncultured_Caudovirales_phage	9.1e-59	35.5
WP_101377737.1\|670966_671518_+\|head,protease	HK97 family phage prohead protease	A0A0M4R4P2	Enterococcus_phage	3.4e-40	48.6
WP_101377738.1\|671553_672678_+\|capsid	phage major capsid protein	D2KRA9	Lactobacillus_phage	2.2e-70	42.7
WP_101377739.1\|672710_672929_+	Ig domain-containing protein	A0A1D6Z291	Staphylococcus_phage	1.9e-10	57.7
WP_096584495.1\|672942_673272_+\|head,tail	phage gp6-like head-tail connector protein	Q0SPK5	Clostridium_phage	1.6e-05	31.9
WP_101377740.1\|673249_673564_+\|head	phage head closure protein	A0A2H4JDE1	uncultured_Caudovirales_phage	3.2e-11	36.4
WP_101377741.1\|673560_673917_+	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	7.0e-15	39.0
WP_101377742.1\|673909_674332_+	hypothetical protein	NA	NA	NA	NA
WP_101377743.1\|674318_674888_+\|tail	phage tail protein	M1PRQ7	Streptococcus_phage	6.5e-47	51.4
WP_101377744.1\|674978_675281_+	hypothetical protein	NA	NA	NA	NA
WP_157769676.1\|675331_675484_+	hypothetical protein	NA	NA	NA	NA
WP_101377745.1\|675499_679819_+\|tail	phage tail tape measure protein	A0A2D1GPD5	Lactobacillus_phage	1.9e-199	51.3
WP_101377746.1\|679811_680525_+\|tail	phage tail protein	A0A1B2APY0	Phage_Wrath	7.9e-42	37.2
WP_101377747.1\|680524_682036_+\|tail	phage tail protein	A0A1B2APX2	Phage_Wrath	4.4e-66	34.9
WP_101377748.1\|682039_684076_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_101377749.1\|684181_684454_+	hypothetical protein	NA	NA	NA	NA
WP_085391429.1\|684458_684698_+\|holin	phage holin	D2J020	Enterococcus_phage	1.8e-19	55.8
WP_101377750.1\|684694_685603_+	N-acetylmuramoyl-L-alanine amidase	Q9MCC8	Lactobacillus_phage	9.1e-59	61.7
WP_101377751.1\|685665_685911_+	hypothetical protein	NA	NA	NA	NA
WP_101377752.1\|685930_686800_-	hypothetical protein	Q938J2	Temperate_phage	5.4e-08	30.3
WP_157826331.1\|686803_687301_-	DUF4065 domain-containing protein	I6R0L8	Salmonella_phage	2.5e-10	31.9
WP_101377754.1\|687502_687763_+	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	7.4e-06	37.9
WP_101377755.1\|687792_688071_+	hypothetical protein	NA	NA	NA	NA
WP_101377756.1\|688115_688298_-	hypothetical protein	NA	NA	NA	NA
WP_101377757.1\|688826_689864_+	sugar-binding domain-containing protein	NA	NA	NA	NA
688460:688477	attR	NA	NA	NA	NA
WP_016264804.1\|689902_690919_+	type I glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_016264805.1\|691019_692234_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_011374315.1\|692259_693015_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_011374316.1\|693132_694428_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	2.2e-167	69.7
WP_099947300.1\|694677_695055_+	VOC family protein	NA	NA	NA	NA
WP_011374319.1\|695102_696158_-	DUF3324 domain-containing protein	NA	NA	NA	NA
WP_101377758.1\|696175_696877_-	WxL domain-containing protein	NA	NA	NA	NA
WP_011374321.1\|696857_697214_-	hypothetical protein	NA	NA	NA	NA
WP_157826332.1\|697235_700079_-	hypothetical protein	NA	NA	NA	NA
WP_025015904.1\|700265_700733_+	arginine repressor	NA	NA	NA	NA
WP_101377760.1\|701004_702156_+\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	6.4e-17	52.3
WP_011374326.1\|702170_702797_+	ABC transporter permease	NA	NA	NA	NA
WP_025015903.1\|702811_703744_+	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_016264813.1\|703740_704400_+	ABC transporter permease	NA	NA	NA	NA
WP_016264814.1\|704553_705444_-	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	4.3e-05	27.2
WP_016264815.1\|705599_707681_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_011374331.1\|707704_708049_+	YlbF family regulator	NA	NA	NA	NA
WP_101377761.1\|708183_709377_+	DNA repair exonuclease	NA	NA	NA	NA
WP_101377762.1\|709379_712091_+	AAA family ATPase	NA	NA	NA	NA
WP_101377763.1\|712080_713049_+	HD domain-containing protein	NA	NA	NA	NA
WP_052006198.1\|713109_714018_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_101377764.1\|714183_714510_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_011374337.1\|714512_714941_-	HIT family protein	NA	NA	NA	NA
WP_016264819.1\|715161_715890_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.5e-22	29.5
WP_101377765.1\|715889_717092_+	ABC transporter permease	NA	NA	NA	NA
WP_011374340.1\|717224_718019_+	phosphotransferase family protein	NA	NA	NA	NA
WP_011374341.1\|718223_718865_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_011374342.1\|718936_719263_-	hypothetical protein	NA	NA	NA	NA
WP_011374343.1\|719385_719706_+	thioredoxin family protein	NA	NA	NA	NA
WP_096585258.1\|719724_720354_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_3

741317 : 749569

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_061827167.1\|741317_742613_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	3.0e-15	30.6
WP_101377770.1\|742683_743409_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	9.2e-38	39.9
WP_101377771.1\|743401_743662_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_101377772.1\|743658_744345_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_101377773.1\|744334_746560_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.7e-151	41.2
WP_101377774.1\|746535_747969_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-50	33.7
WP_101377775.1\|747974_749003_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.5e-65	44.6
WP_101377776.1\|748999_749569_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	5.4e-25	34.9

DBSCAN-SWA_4

875227 : 964222

102

Lactobacillus_phage(42.11%)

holin,integrase,tRNA,capsid,terminase,portal,tail

attL 881987:882002|attR 937960:937975

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076631886.1\|875227_876367_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_016264980.1\|876525_877176_+	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_035147215.1\|877191_878382_+	phosphopentomutase	NA	NA	NA	NA
WP_016264982.1\|878398_879103_+	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_016264983.1\|879124_880354_+	nucleoside transporter	NA	NA	NA	NA
WP_035147217.1\|880377_881652_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.1e-24	24.9
881987:882002	attL	NA	NA	NA	NA
WP_016264986.1\|882652_883951_+	pyrimidine-nucleoside phosphorylase	A0A0H3UZD4	Geobacillus_virus	1.4e-121	54.0
WP_025015827.1\|884187_885522_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_016264988.1\|885674_886334_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_101377818.1\|886345_887005_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_056936400.1\|887010_889539_+	ATP-dependent RecD-like DNA helicase	A0A1P8DII4	Virus_Rctr197k	2.0e-42	29.3
WP_011374512.1\|889581_890793_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_035147235.1\|890853_891093_-	hypothetical protein	NA	NA	NA	NA
WP_101377819.1\|891095_892190_-\|integrase	site-specific integrase	Q9ZXG6	Leuconostoc_phage	2.2e-43	35.8
WP_085391709.1\|892391_893321_-	hypothetical protein	NA	NA	NA	NA
WP_085391710.1\|893456_894128_-	LexA family transcriptional regulator	B4XYR6	Lactobacillus_phage	5.7e-42	44.0
WP_085391711.1\|894294_894525_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_101377820.1\|894537_894804_+	hypothetical protein	NA	NA	NA	NA
WP_157826333.1\|894816_895011_-	hypothetical protein	NA	NA	NA	NA
WP_101377822.1\|895057_895804_+	phage antirepressor KilAC domain-containing protein	B8R674	Lactobacillus_phage	3.3e-91	67.2
WP_157826334.1\|895819_895981_+	hypothetical protein	NA	NA	NA	NA
WP_101377823.1\|895967_896513_-	hypothetical protein	NA	NA	NA	NA
WP_035147721.1\|896601_896829_+	hypothetical protein	NA	NA	NA	NA
WP_101377824.1\|896828_897146_+	hypothetical protein	NA	NA	NA	NA
WP_094365699.1\|897142_897322_+	hypothetical protein	NA	NA	NA	NA
WP_157826335.1\|897432_898029_+	host-nuclease inhibitor Gam family protein	A0A0K2CZ48	Paenibacillus_phage	2.8e-24	36.9
WP_052039318.1\|898031_898997_+	AAA family ATPase	A0A0S2SY47	Bacillus_phage	7.4e-59	39.6
WP_101377825.1\|898993_899737_+	hypothetical protein	U5U4M2	Lactobacillus_phage	2.7e-48	43.0
WP_082268162.1\|899711_900455_+	conserved phage C-terminal domain-containing protein	Q6SEE7	Lactobacillus_prophage	3.2e-54	50.4
WP_101377826.1\|900435_901272_+	ATP-binding protein	O03914	Lactobacillus_phage	1.1e-66	52.0
WP_101377827.1\|901380_901794_+	RusA family crossover junction endodeoxyribonuclease	A8YQM5	Lactobacillus_phage	3.6e-31	50.0
WP_101377828.1\|901783_902008_+	hypothetical protein	NA	NA	NA	NA
WP_094365705.1\|902019_902493_+	single-stranded DNA-binding protein	A0A2D1GPB7	Lactobacillus_phage	3.5e-46	61.8
WP_101377829.1\|902505_903222_+	hypothetical protein	NA	NA	NA	NA
WP_101377830.1\|903241_903655_+	DUF1642 domain-containing protein	NA	NA	NA	NA
WP_101377831.1\|903642_903837_+	hypothetical protein	NA	NA	NA	NA
WP_076981442.1\|904041_904221_+	hypothetical protein	NA	NA	NA	NA
WP_101378102.1\|904474_905635_+	DNA (cytosine-5-)-methyltransferase	A0A2H4PBE1	Lactobacillus_phage	3.2e-109	52.9
WP_101377833.1\|905859_906114_+	hypothetical protein	A0A291I9M4	Lactobacillus_phage	1.4e-17	57.1
WP_101377835.1\|906313_906643_+	hypothetical protein	A0A2K9V545	Lactobacillus_phage	1.4e-25	61.6
WP_157826336.1\|906642_906795_+	hypothetical protein	NA	NA	NA	NA
WP_101377836.1\|906873_907305_+	transcriptional regulator	O03925	Lactobacillus_phage	7.7e-32	48.9
WP_157771197.1\|907812_907959_+	hypothetical protein	NA	NA	NA	NA
WP_099960234.1\|907991_908486_+\|terminase	terminase small subunit	O03926	Lactobacillus_phage	4.8e-46	61.0
WP_101377837.1\|908463_909783_+\|terminase	PBSX family phage terminase large subunit	U3PBE8	Lactobacillus_phage	9.5e-150	57.5
WP_101377838.1\|909791_911315_+\|portal	phage portal protein	Q938L2	Temperate_phage	1.5e-122	47.7
WP_101377839.1\|911314_912439_+\|capsid	phage minor capsid protein	U3PFU0	Lactobacillus_phage	4.6e-68	39.3
WP_157826337.1\|912532_913150_+	phage scaffolding protein	O03931	Lactobacillus_phage	3.9e-13	38.2
WP_099960239.1\|913154_913979_+\|capsid	N4-gp56 family major capsid protein	Q9AZ61	Lactococcus_phage	4.2e-95	69.8
WP_101377841.1\|914046_914451_+	hypothetical protein	C5IUJ7	Streptococcus_phage	2.4e-11	33.1
WP_101377842.1\|914443_914788_+	hypothetical protein	O03932	Lactobacillus_phage	3.1e-07	32.3
WP_101378103.1\|914796_915123_+\|capsid	capsid protein	Q5YA66	Bacillus_phage	4.0e-25	49.5
WP_101377843.1\|915122_915515_+\|capsid	capsid protein	Q5YA65	Bacillus_phage	7.7e-31	46.9
WP_101377844.1\|915525_915972_+\|tail	phage tail protein	A0A1S5SEC5	Streptococcus_phage	2.5e-30	51.7
WP_101377845.1\|916111_916576_+	hypothetical protein	NA	NA	NA	NA
WP_101377846.1\|916586_917189_+	hypothetical protein	Q938K4	Temperate_phage	5.7e-25	35.2
WP_157826338.1\|917181_920253_+	tape measure protein	D2IYX6	Enterococcus_phage	1.7e-77	53.1
WP_101377848.1\|920236_920962_+\|tail	phage tail family protein	A0A1B2APY0	Phage_Wrath	4.6e-53	43.2
WP_101377849.1\|920961_922473_+\|tail	phage tail protein	A0A1B2APX2	Phage_Wrath	1.2e-82	39.5
WP_101377850.1\|922472_923297_+	hypothetical protein	NA	NA	NA	NA
WP_101377851.1\|923302_924508_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_101377852.1\|924613_924871_+	hemolysin XhlA family protein	NA	NA	NA	NA
WP_101377853.1\|924874_925084_+\|holin	holin	A0A2H4IZQ3	uncultured_Caudovirales_phage	2.3e-05	45.9
WP_173674926.1\|925143_925983_+	N-acetylmuramoyl-L-alanine amidase	Q9MCC8	Lactobacillus_phage	4.8e-46	47.5
WP_085845076.1\|926430_926970_+	hypothetical protein	NA	NA	NA	NA
WP_101377855.1\|927423_928035_+	LysE family transporter	NA	NA	NA	NA
WP_101377856.1\|928127_929240_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_099960278.1\|929418_930135_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_011374517.1\|930136_930691_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011374518.1\|930958_931414_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_011374519.1\|931424_932405_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_016264998.1\|932446_932686_+	acyl carrier protein	NA	NA	NA	NA
WP_016264999.1\|932823_933768_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_016265000.1\|933767_934499_+	3-oxoacyl-[acyl-carrier-protein] reductase	Q06VL0	Trichoplusia_ni_ascovirus	2.4e-17	29.6
WP_025015824.1\|934512_935745_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_016265002.1\|935749_936205_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_011374525.1\|936208_936631_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_035147508.1\|936644_937991_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
937960:937975	attR	NA	NA	NA	NA
WP_016265005.1\|938834_939632_+	acetyl-CoA carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_016265006.1\|939655_940405_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_101377857.1\|940410_941166_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_101377858.1\|941184_941718_+	biotin transporter BioY	NA	NA	NA	NA
WP_076645535.1\|941832_942975_+	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_011374534.1\|943038_943509_+	GAF domain-containing protein	NA	NA	NA	NA
WP_011374535.1\|943546_944092_-	ECF transporter S component	NA	NA	NA	NA
WP_076645533.1\|944104_945079_-	nucleoside hydrolase	NA	NA	NA	NA
WP_076645839.1\|945535_946138_-	nitroreductase family protein	NA	NA	NA	NA
WP_076645837.1\|946465_947440_+	DUF2785 domain-containing protein	NA	NA	NA	NA
WP_016265014.1\|947466_948117_+	HAD family phosphatase	M1IMD4	Acanthocystis_turfacea_Chlorella_virus	6.0e-12	25.8
WP_025015819.1\|948256_949111_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011374541.1\|949153_949648_-	universal stress protein	NA	NA	NA	NA
WP_016265016.1\|949710_949986_-	hypothetical protein	NA	NA	NA	NA
WP_011374543.1\|950300_951581_-	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	6.1e-101	48.4
WP_101377859.1\|951713_953993_+	bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB	NA	NA	NA	NA
WP_016265018.1\|954045_954489_-	YueI family protein	NA	NA	NA	NA
WP_056948499.1\|954559_955165_+	DUF1054 domain-containing protein	NA	NA	NA	NA
WP_011374547.1\|955260_955866_-	30S ribosomal protein S4	NA	NA	NA	NA
WP_016265020.1\|956238_957951_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_016265021.1\|958110_959259_+	cysteine desulfurase	NA	NA	NA	NA
WP_011374550.1\|959283_960501_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_101377860.1\|960628_961255_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_016265024.1\|961573_964222_+\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.3e-158	42.3

DBSCAN-SWA_5

1120496 : 1127817

Staphylococcus_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_101378109.1\|1120496_1121342_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	7.7e-20	44.2
WP_035145821.1\|1121538_1122039_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	3.5e-28	38.7
WP_101377896.1\|1122049_1123000_-	thymidylate synthase	A0A0N9SH48	Staphylococcus_phage	4.2e-123	65.0
WP_096584937.1\|1123071_1124961_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.0e-48	29.3
WP_011374705.1\|1125073_1125535_-	hypothetical protein	NA	NA	NA	NA
WP_056947591.1\|1125603_1126797_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	1.9e-43	50.5
WP_096584934.1\|1126944_1127817_+	YitT family protein	M1Q1P6	Streptococcus_phage	8.2e-57	41.5

DBSCAN-SWA_6

1276099 : 1337018

Lactobacillus_phage(39.39%)

holin,protease,integrase,capsid,terminase,portal,tail

attL 1272876:1272890|attR 1341443:1341457

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1272876:1272890	attL	NA	NA	NA	NA
WP_099947544.1\|1276099_1276711_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_101377913.1\|1276731_1277052_+	hypothetical protein	NA	NA	NA	NA
WP_049762129.1\|1277223_1277877_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_011374855.1\|1278002_1278425_-	methylglyoxal synthase	NA	NA	NA	NA
WP_101377915.1\|1278436_1279198_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_101377916.1\|1279337_1280033_-	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	8.1e-15	60.0
WP_011374858.1\|1280746_1280998_-	hypothetical protein	NA	NA	NA	NA
WP_101377917.1\|1281224_1281599_-	hypothetical protein	NA	NA	NA	NA
WP_011374860.1\|1281591_1282896_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.3e-85	39.9
WP_011374861.1\|1282895_1283141_-	hypothetical protein	NA	NA	NA	NA
WP_101377918.1\|1283160_1283535_-	hypothetical protein	NA	NA	NA	NA
WP_056948015.1\|1283561_1284257_-	LysM peptidoglycan-binding domain-containing protein	A0A096XT26	Enterococcus_phage	5.0e-17	40.3
WP_011374864.1\|1284500_1286543_-	potassium transporter Kup	M1IAJ4	Acanthocystis_turfacea_Chlorella_virus	8.9e-70	35.5
WP_011374865.1\|1286700_1286874_+	hypothetical protein	NA	NA	NA	NA
WP_011374866.1\|1287006_1287486_+	nucleoside 2-deoxyribosyltransferase	A0A2P0ZL88	Lactobacillus_phage	1.5e-15	35.4
WP_101377919.1\|1287537_1288911_-	glycoside hydrolase family 1 protein	A0A0B5JD41	Pandoravirus	3.9e-45	30.4
WP_016265287.1\|1289261_1289981_-	aquaporin family protein	M1HQB9	Paramecium_bursaria_Chlorella_virus	2.4e-22	30.2
WP_101377920.1\|1290197_1290869_+	hypothetical protein	NA	NA	NA	NA
WP_035146201.1\|1290993_1291686_+	hypothetical protein	NA	NA	NA	NA
WP_016265290.1\|1291908_1292343_+	universal stress protein	NA	NA	NA	NA
WP_173674922.1\|1292602_1292746_+	hypothetical protein	NA	NA	NA	NA
WP_016265292.1\|1292884_1293091_+	hypothetical protein	NA	NA	NA	NA
WP_035146195.1\|1293151_1293742_+	C39 family peptidase	NA	NA	NA	NA
WP_101377921.1\|1293763_1294483_+	hypothetical protein	NA	NA	NA	NA
WP_016265295.1\|1294504_1294816_+	hypothetical protein	NA	NA	NA	NA
WP_157826342.1\|1295216_1295525_-	hypothetical protein	NA	NA	NA	NA
WP_101377923.1\|1295602_1296499_-	Fic family protein	Q9AZ49	Lactococcus_phage	1.8e-51	40.7
WP_101377924.1\|1296818_1297049_-	hypothetical protein	NA	NA	NA	NA
WP_101377925.1\|1297078_1297339_-	hypothetical protein	A0A0S2MYI8	Enterococcus_phage	7.4e-06	37.9
WP_157826343.1\|1297445_1298258_+	hypothetical protein	NA	NA	NA	NA
WP_101377927.1\|1298331_1299468_-	LysM peptidoglycan-binding domain-containing protein	Q6J1W8	Lactobacillus_phage	7.9e-36	32.6
WP_101377928.1\|1299454_1299868_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_101377929.1\|1299961_1300195_-	hypothetical protein	NA	NA	NA	NA
WP_101377930.1\|1300194_1300644_-	DUF1617 family protein	A0A2P0ZLE0	Lactobacillus_phage	2.3e-18	38.7
WP_101377931.1\|1300643_1300847_-	hypothetical protein	NA	NA	NA	NA
WP_101377932.1\|1300836_1305621_-\|tail	phage tail protein	Q938K1	Temperate_phage	1.5e-75	34.7
WP_157826344.1\|1305617_1306340_-\|tail	phage tail family protein	NA	NA	NA	NA
WP_101377934.1\|1306339_1310833_-\|tail	phage tail tape measure protein	A0A2P0ZLF1	Lactobacillus_phage	2.3e-86	34.3
WP_101377935.1\|1310840_1311491_-	hypothetical protein	A0A1B1P868	Bacillus_phage	1.3e-14	31.2
WP_101377936.1\|1311477_1312047_-	hypothetical protein	NA	NA	NA	NA
WP_101377937.1\|1312163_1312751_-	hypothetical protein	NA	NA	NA	NA
WP_101377938.1\|1312762_1313197_-	hypothetical protein	NA	NA	NA	NA
WP_157826345.1\|1313186_1313546_-	hypothetical protein	NA	NA	NA	NA
WP_101377940.1\|1313538_1313895_-	hypothetical protein	NA	NA	NA	NA
WP_101377941.1\|1313894_1314299_-	hypothetical protein	NA	NA	NA	NA
WP_101377942.1\|1314298_1314505_-	hypothetical protein	NA	NA	NA	NA
WP_101377943.1\|1314601_1315468_-\|capsid	N4-gp56 family major capsid protein	A8ASJ6	Listeria_phage	7.3e-90	63.2
WP_101377944.1\|1315479_1316064_-	hypothetical protein	NA	NA	NA	NA
WP_157826346.1\|1316128_1316290_-	hypothetical protein	NA	NA	NA	NA
WP_101377945.1\|1316292_1317387_-	hypothetical protein	Q9T1B9	Listeria_phage	6.7e-40	32.2
WP_101377946.1\|1317346_1318921_-\|portal	phage portal protein	B5LPR1	Bacillus_virus	1.5e-93	39.4
WP_101377947.1\|1318933_1320247_-\|terminase	PBSX family phage terminase large subunit	A0A1S5SA45	Streptococcus_phage	1.3e-138	57.8
WP_101377948.1\|1320246_1321086_-\|terminase	small subunit of terminase	D2J000	Enterococcus_phage	7.1e-42	39.1
WP_101377949.1\|1321124_1321367_-	hypothetical protein	NA	NA	NA	NA
WP_101377950.1\|1321514_1321763_-	DUF2829 domain-containing protein	A0A2P1CCQ6	Klebsiella_phage	1.1e-09	43.2
WP_101377951.1\|1321983_1322790_-	hypothetical protein	NA	NA	NA	NA
WP_101377952.1\|1323393_1323819_-	transcriptional regulator	O03925	Lactobacillus_phage	9.2e-30	47.1
WP_157826347.1\|1324016_1324160_-	hypothetical protein	NA	NA	NA	NA
WP_101377953.1\|1324159_1324411_-	hypothetical protein	A0A2K9VC51	Lactobacillus_phage	9.0e-17	54.4
WP_157826348.1\|1324559_1324922_-	hypothetical protein	A0A0E3Y4X1	Fusobacterium_phage	2.3e-13	39.2
WP_101377955.1\|1324932_1325439_-	hypothetical protein	NA	NA	NA	NA
WP_101377956.1\|1325557_1326043_-	DUF1642 domain-containing protein	NA	NA	NA	NA
WP_157826349.1\|1326164_1326326_-	hypothetical protein	NA	NA	NA	NA
WP_061827077.1\|1326364_1326547_-	hypothetical protein	NA	NA	NA	NA
WP_157826350.1\|1326573_1326726_-	hypothetical protein	NA	NA	NA	NA
WP_101377957.1\|1326722_1327082_-	hypothetical protein	NA	NA	NA	NA
WP_101377958.1\|1327078_1328035_-	DnaD domain protein	A0A0B5D175	Listeria_phage	5.5e-46	37.1
WP_101377959.1\|1328055_1328505_-	single-stranded DNA-binding protein	A0A2D1GPB7	Lactobacillus_phage	4.8e-45	58.4
WP_101377960.1\|1328494_1329181_-	hypothetical protein	E9LUU3	Lactobacillus_phage	4.0e-51	47.3
WP_101377961.1\|1329177_1329900_-	ERF family protein	D6PSU1	Lactobacillus_phage	2.0e-48	49.8
WP_101377962.1\|1329912_1330860_-	DUF1351 domain-containing protein	U5U3Y3	Lactobacillus_phage	6.4e-31	32.0
WP_101377963.1\|1330846_1331122_-	hypothetical protein	NA	NA	NA	NA
WP_101377964.1\|1331225_1331408_-	hypothetical protein	NA	NA	NA	NA
WP_101377965.1\|1331404_1331659_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_101377966.1\|1331661_1332177_-	hypothetical protein	A0A0N7IR93	Lactobacillus_phage	4.3e-21	34.9
WP_157826351.1\|1332257_1332422_-	hypothetical protein	NA	NA	NA	NA
WP_101377967.1\|1332458_1332656_-	helix-turn-helix transcriptional regulator	A0A1B0Y2Q9	Lactobacillus_phage	1.5e-06	46.6
WP_101377968.1\|1332796_1333123_+	helix-turn-helix transcriptional regulator	A0A059T669	Listeria_phage	7.1e-22	53.8
WP_101377969.1\|1333134_1333596_+	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTX7	Clostridium_phage	4.2e-20	47.9
WP_101377970.1\|1333615_1334503_+	hypothetical protein	NA	NA	NA	NA
WP_101377971.1\|1334582_1335119_+	hypothetical protein	NA	NA	NA	NA
WP_101377972.1\|1335284_1335704_+	hypothetical protein	NA	NA	NA	NA
WP_101377973.1\|1335800_1337018_+\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	2.4e-94	45.9
1341443:1341457	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1418746 : 1426855

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099947689.1\|1418746_1420492_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.0e-46	27.9
WP_101377985.1\|1420633_1420864_-	YneF family protein	NA	NA	NA	NA
WP_011374971.1\|1420944_1421187_-	DUF896 domain-containing protein	NA	NA	NA	NA
WP_011374972.1\|1421321_1421936_+	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	1.1e-15	58.2
WP_011374973.1\|1422069_1422588_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.4e-26	41.3
WP_025016402.1\|1422611_1424924_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.8e-77	30.9
WP_035146095.1\|1425068_1426061_+	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	2.9e-50	37.0
WP_011374976.1\|1426146_1426512_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_011374977.1\|1426528_1426855_+	heavy metal-binding domain-containing protein	M4STD1	Rhodobacter_phage	5.4e-06	34.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LT960781

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection