CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LT992435	Staphylococcus aureus isolate 1549-SCV chromosome I	4 crisprs	DEDDh,DinG,cas3,csa3,WYL	2	0	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LT992435_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT992435_1

1239985-1240123

Orphan

Consensus_repeat	Method
TTTTTAATATTTTTCTTTTGAGTTACTCGAAAATTTTTCTCTTTACTCGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT992435_1

>merge|NZ_LT992435|1|1239985-1240123|CRISPRCasFinder
TTTTTAATATTTTTCTTTTGAGTTACTCGAAAATTTTTCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCATTGGTTTCCCATGATTTTTAATATTTTTCTTTTAAGTTACTCGAAAATTTTTCTCTTTACTCGAA

>NZ_LT992435|1|1|1239985-1240123|CRISPRCasFinder
TTTTTAATATTTTTCTTTTGAGTTACTCGAAAATTTTTCTCTTTACTCGAA	AGCTCACAAAACCCTTGATATCATTGGTTTCCCATGA
TTTTTAATATTTTTCTTTTAAGTTACTCGAAAATTTTTCTCTTTACTCGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT992435.1\|WP_000027572.1\|1244592_1245453_-\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|184205
NZ_LT992435.1\|WP_115657076.1\|1232311_1233829_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340855
NZ_LT992435.1\|WP_000222277.1\|1227675_1230096_+\|polysaccharide-lyase-8-family-protein	unknown	unknown	gnl\|CDD\|238517
NZ_LT992435.1\|WP_001044440.1\|1230294_1231149_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223810
NZ_LT992435.1\|WP_000101625.1\|1248199_1248589_-\|30S-ribosomal-protein-S11	unknown	unknown	gnl\|CDD\|180007
NZ_LT992435.1\|WP_000791632.1\|1243796_1244603_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NZ_LT992435.1\|WP_001221849.1\|1242988_1243792_-\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NZ_LT992435.1\|WP_000143638.1\|1232023_1232302_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_001622005.1\|1238658_1238859_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_001250038.1\|1242311_1242749_-\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NZ_LT992435.1\|WP_000655242.1\|1238840_1239023_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_000044372.1\|1234053_1234869_-\|HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319792
NZ_LT992435.1\|WP_000868342.1\|1249000_1249114_-\|50S-ribosomal-protein-L36	unknown	unknown	gnl\|CDD\|179039
NZ_LT992435.1\|WP_000090796.1\|1248612_1248978_-\|30S-ribosomal-protein-S13	unknown	unknown	gnl\|CDD\|235358
NZ_LT992435.1\|WP_000170975.1\|1241899_1242298_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NZ_LT992435.1\|WP_000569649.1\|1247180_1248125_-\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NZ_LT992435.1\|WP_000130128.1\|1236705_1238370_-\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
NZ_LT992435.1\|WP_000769707.1\|1235163_1235589_+\|MAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367591
NZ_LT992435.1\|WP_000542274.1\|1246795_1247164_-\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
NZ_LT992435.1\|WP_000186132.1\|1235964_1236669_-\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058

Protein	Function_ID	Function_description	E-value
NZ_LT992435.1\|WP_000027572.1\|1244592_1245453_-\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
NZ_LT992435.1\|WP_115657076.1\|1232311_1233829_+\|glycosyltransferase	gnl\|CDD\|340855	cd04949, GT4_GtfA-like, accessory Sec system glycosyltransferase GtfA and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.	2.32057e-60
NZ_LT992435.1\|WP_000542274.1\|1246795_1247164_-\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
NZ_LT992435.1\|WP_001044440.1\|1230294_1231149_-\|M23-family-metallopeptidase	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	7.53812e-24
NZ_LT992435.1\|WP_000791632.1\|1243796_1244603_-\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	5.04502e-49
NZ_LT992435.1\|WP_001221849.1\|1242988_1243792_-\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	3.32017e-120
NZ_LT992435.1\|WP_000170975.1\|1241899_1242298_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	2.2295e-82
NZ_LT992435.1\|WP_001250038.1\|1242311_1242749_-\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
NZ_LT992435.1\|WP_000044372.1\|1234053_1234869_-\|HAD-IIB-family-hydrolase	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.68683e-98
NZ_LT992435.1\|WP_000868342.1\|1249000_1249114_-\|50S-ribosomal-protein-L36	gnl\|CDD\|179039	PRK00465, rpmJ, 50S ribosomal protein L36; Reviewed.	9.31781e-13
NZ_LT992435.1\|WP_000090796.1\|1248612_1248978_-\|30S-ribosomal-protein-S13	gnl\|CDD\|235358	PRK05179, rpsM, 30S ribosomal protein S13; Validated.	2.16257e-78
NZ_LT992435.1\|WP_000222277.1\|1227675_1230096_+\|polysaccharide-lyase-8-family-protein	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
NZ_LT992435.1\|WP_000569649.1\|1247180_1248125_-\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	1.89947e-175
NZ_LT992435.1\|WP_000130128.1\|1236705_1238370_-\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
NZ_LT992435.1\|WP_000769707.1\|1235163_1235589_+\|MAP-domain-containing-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	6.70728e-35
NZ_LT992435.1\|WP_000101625.1\|1248199_1248589_-\|30S-ribosomal-protein-S11	gnl\|CDD\|180007	PRK05309, PRK05309, 30S ribosomal protein S11; Validated.	2.01588e-89
NZ_LT992435.1\|WP_000186132.1\|1235964_1236669_-\|acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.05414e-118

>NZ_LT992435.1|WP_000655242.1|1238840_1239023_-|hypothetical-protein
MKDSIFWKKAFIPVYFIVAMLVFLLFRFYIKTDNFSIYLMIIFLICLGTASIIYNYKTNR
>NZ_LT992435.1|WP_001622005.1|1238658_1238859_+|hypothetical-protein
MSLSLVFSRWRFEIVVLWWNEFVVLWRYKNAVLWQFQNGVSIKKSQQDLELTVTYTFHTYIYRLVL
>NZ_LT992435.1|WP_000130128.1|1236705_1238370_-|acetolactate-synthase-AlsS
MTDKKYTAADIVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGIVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>NZ_LT992435.1|WP_000186132.1|1235964_1236669_-|acetolactate-decarboxylase
MTNVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHIRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTNANIDYKDISDEIREAE
>NZ_LT992435.1|WP_000769707.1|1235163_1235589_+|MAP-domain-containing-protein
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNLIDPSTIKQIQIVVK
>NZ_LT992435.1|WP_000044372.1|1234053_1234869_-|HAD-IIB-family-hydrolase
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVMTAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSIGNHNKDRRILESLVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>NZ_LT992435.1|WP_115657076.1|1232311_1233829_+|glycosyltransferase
MTTYMLMYSIPEKAGGITSVMLNRSKLLAEKGYSCALLTLDDKNYDPLRAKLTNSGRLHKEVKIVNLYEELKMLYDVENTEIENKNMQTFEKLNLLNQEGFYIQKDEYEEKKYARYFKDNNYIMYKKWINGQLSHIDYFQNRKRIKRHVFQNKILRKEITFNDKNKMSEVKYLSNDGFCYLSYWYGDNENIVNIFYFDKNSKEVLNFKNNKMFHSYWLDKNLTSNDVLILDGIGTYPKVENMQSNDVKKIFTIHTNHFLSPYSYGAEIKPEFRNMLLNLKELDTLVVLTKEQKDDIIKQFGDYNNIKVIPNAVSFEENLTQNIREKNSIIVLQRFVAMKNITHIISAINIVRKKVKDVKLHIYGTGTQKENYTKLIKKLKLQDNVFIHDYAFDIRGLYTKASLSVLTSDYEGLPMSLLEAMSYGVPVISYPINYGPKSIIQNNINGIITKKKDNINELAKKIIHVLKKETLISQFSENARTTIKTNFSYEAVSKKWIELIDEKSK
>NZ_LT992435.1|WP_000143638.1|1232023_1232302_+|hypothetical-protein
MTFNEYNYNNELILKLNKIEVQKNNEKISEVFKDYEILKPKIVFNGSNPYLALNHIIVAEIENYSSLETFSKIYVDEDYYYNYGELIIKCKK
>NZ_LT992435.1|WP_001044440.1|1230294_1231149_-|M23-family-metallopeptidase
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTRQSDVHELKVCTQNDDTMEQIWIDKAKQFGVSVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKKQGKVNTDYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFLNNRELIKGDVVCGLQGE
>NZ_LT992435.1|WP_000222277.1|1227675_1230096_+|polysaccharide-lyase-8-family-protein
MTYRMKKWQKLSTITLLMAGVITLSDGEFRSVDKHQIAVADTNTQTPNYEKLKNTWLDVNYGYDKYDESNPDMKKKFEATENEAKKLLSEMKTESGRTYLWESSKDIDTKSADMTRTYRNIEKIAEAMNHPKTTLKNDENKKKLKDALEWLHKNAYGKDPDKKVADLKTNFSKSAPQKNTNLNWWDYEIGTPKSLTNTLILLNGDISSDEKKKYTAPIKTFAPKSDEILSSVGKAEPAKGGNLVDIAKVKLLESIIEEDKDMTKNSIDSFNKVFTYVQSNSTGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFKETSQNDTILKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASVTVMKSLLRLSDAMDESTKAKYKKIVKTSVKSDSSYKQNDYLSSYSDISKMKALMEDSTLSTNDLTQQLKIYNDMDRVTYHNKDLDFAFGLSMTSKNVARYESINNENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKENKNSDKTFVGGTKFDDQHASIGMEFENQDKTLTAKKSYFILNDKIVFLGTGIKNTDSSMNPVTTIENRKANGYTLYTDDKQTTNSDNQETNSVFLESTDTKKNIGYHFLNKSKINVKKESHTGKWSEINKSQKTEDKKDEYYEVTQKHSNSDNKYGYVLYPSLSKDVFKSKASQVTVVKQDDDFHVVKDNESVWAGVNYSDSAKTFEINGTKVEVKAKGMFILKKKDDKTYECSFYNPESTNTASDIESKISMTGYSITNKNASTTNESGVRFELTK
>NZ_LT992435.1|WP_000170975.1|1241899_1242298_-|30S-ribosomal-protein-S9
MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>NZ_LT992435.1|WP_001250038.1|1242311_1242749_-|50S-ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>NZ_LT992435.1|WP_001221849.1|1242988_1243792_-|tRNA-pseudouridine(38-40)-synthase-TruA
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNKAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEISDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND
>NZ_LT992435.1|WP_000791632.1|1243796_1244603_-|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MKNKLIIGRYLPNDSYVHHLDPRAKLMFVFLFIILIFVCHSPLTYLWVFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>NZ_LT992435.1|WP_000027572.1|1244592_1245453_-|energy-coupling-factor-transporter-ATPase
MSIRFNDVSYTYQQGTPYEHQAIHDINTEFEQGKYYAIVGQTGSGKSTLIQNINALIKPTSGTVTIDDVTVTHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMDLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSVLAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKEKEKLAGWHIGLPDIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>NZ_LT992435.1|WP_000542274.1|1246795_1247164_-|50S-ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV
>NZ_LT992435.1|WP_000569649.1|1247180_1248125_-|DNA-directed-RNA-polymerase-subunit-alpha
MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
>NZ_LT992435.1|WP_000101625.1|1248199_1248589_-|30S-ribosomal-protein-S11
MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVTPVPHNGCRPPKRRRV
>NZ_LT992435.1|WP_000090796.1|1248612_1248978_-|30S-ribosomal-protein-S13
MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTRVKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKTKNNARTRKGPVKTVANKKK
>NZ_LT992435.1|WP_000868342.1|1249000_1249114_-|50S-ribosomal-protein-L36
MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG

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Crispr_ID: NZ_LT992435_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT992435_2

1430970-1431063

Orphan

Consensus_repeat	Method
TTCTTCAAATTTATTTGTTAGAAAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT992435_2

>merge|NZ_LT992435|2|1430970-1431063|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGGCTTATGCAGTTGACGTTTTACGTCCAACTGCGTTCCTCCGTCTTCTTCAAATTTATTTGTTAGAAAGG

>NZ_LT992435|2|2|1430970-1431063|CRISPRCasFinder
TTCTTCAAATTTATTTGTTAGAAAGG	CTTATGCAGTTGACGTTTTACGTCCAACTGCGTTCCTCCGTC
TTCTTCAAATTTATTTGTTAGAAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT992435.1\|WP_000019132.1\|1429962_1430829_-\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_LT992435.1\|WP_000825936.1\|1426178_1426958_-\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270429
NZ_LT992435.1\|WP_001046647.1\|1439061_1440069_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NZ_LT992435.1\|WP_000916696.1\|1434802_1435750_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	unknown	unknown	gnl\|CDD\|369625
NZ_LT992435.1\|WP_001125208.1\|1428949_1429636_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518
NZ_LT992435.1\|WP_000286884.1\|1437265_1437958_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NZ_LT992435.1\|WP_001110067.1\|1440070_1441429_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NZ_LT992435.1\|WP_000762708.1\|1428691_1428796_+\|putative-metal-homeostasis-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_000615468.1\|1424750_1425482_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LT992435.1\|WP_001056918.1\|1435751_1436729_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NZ_LT992435.1\|WP_000038955.1\|1427078_1428518_-\|multidrug-efflux-MFS-transporter-MdeA	unknown	unknown	gnl\|CDD\|129794
NZ_LT992435.1\|WP_000479573.1\|1425478_1426198_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_LT992435.1\|WP_076686211.1\|1423403_1424654_+\|FemA/FemB-family-glycyltransferase-FmhA	unknown	unknown	gnl\|CDD\|367067
NZ_LT992435.1\|WP_000594516.1\|1433305_1434235_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	unknown	unknown	gnl\|CDD\|369625
NZ_LT992435.1\|WP_000971558.1\|1437968_1439084_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NZ_LT992435.1\|WP_000792549.1\|1431456_1432770_+\|B-domain-containing-protein	unknown	unknown	gnl\|CDD\|288473
NZ_LT992435.1\|WP_000819842.1\|1422786_1423149_-\|DUF4467-domain-containing-protein	unknown	unknown	gnl\|CDD\|291399
NZ_LT992435.1\|WP_000162809.1\|1422168_1422768_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NZ_LT992435.1\|WP_001791249.1\|1431257_1431362_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_000200952.1\|1436787_1437255_-\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623

Protein	Function_ID	Function_description	E-value
NZ_LT992435.1\|WP_000019132.1\|1429962_1430829_-\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.98386e-90
NZ_LT992435.1\|WP_000825936.1\|1426178_1426958_-\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.4238e-99
NZ_LT992435.1\|WP_001046647.1\|1439061_1440069_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NZ_LT992435.1\|WP_000916696.1\|1434802_1435750_+\|bi-component-gamma-hemolysin-HlgCB-subunit-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.96123e-92
NZ_LT992435.1\|WP_001125208.1\|1428949_1429636_-\|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167
NZ_LT992435.1\|WP_000286884.1\|1437265_1437958_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	4.99039e-130
NZ_LT992435.1\|WP_000615468.1\|1424750_1425482_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.59267e-145
NZ_LT992435.1\|WP_001056918.1\|1435751_1436729_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	4.68948e-128
NZ_LT992435.1\|WP_000038955.1\|1427078_1428518_-\|multidrug-efflux-MFS-transporter-MdeA	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.17835e-92
NZ_LT992435.1\|WP_000479573.1\|1425478_1426198_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	8.38308e-78
NZ_LT992435.1\|WP_000200952.1\|1436787_1437255_-\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00103624
NZ_LT992435.1\|WP_000594516.1\|1433305_1434235_+\|bi-component-gamma-hemolysin-HlgAB-subunit-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	2.15607e-97
NZ_LT992435.1\|WP_000971558.1\|1437968_1439084_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	5.99985e-138
NZ_LT992435.1\|WP_000792549.1\|1431456_1432770_+\|B-domain-containing-protein	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	7.22146e-28
NZ_LT992435.1\|WP_000819842.1\|1422786_1423149_-\|DUF4467-domain-containing-protein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	1.83927e-31
NZ_LT992435.1\|WP_000162809.1\|1422168_1422768_-\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	7.90499e-30
NZ_LT992435.1\|WP_076686211.1\|1423403_1424654_+\|FemA/FemB-family-glycyltransferase-FmhA	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
NZ_LT992435.1\|WP_001110067.1\|1440070_1441429_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0

>NZ_LT992435.1|WP_000019132.1|1429962_1430829_-|cation-transporter
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNEITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>NZ_LT992435.1|WP_001125208.1|1428949_1429636_-|2,3-diphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>NZ_LT992435.1|WP_000762708.1|1428691_1428796_+|putative-metal-homeostasis-protein
MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK
>NZ_LT992435.1|WP_000038955.1|1427078_1428518_-|multidrug-efflux-MFS-transporter-MdeA
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGIVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIEMMNQIKIDTMLHGYHAGFLFALLITVISFFCSFMLQGKKKEVDSHQ
>NZ_LT992435.1|WP_000825936.1|1426178_1426958_-|transporter-substrate-binding-domain-containing-protein
MKRLLFVVIAFVFILAACGNNSSKDKEASKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKAEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSKSAFAFSKKVDDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>NZ_LT992435.1|WP_000479573.1|1425478_1426198_-|amino-acid-ABC-transporter-permease
MFLNLNSEQLHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKVLRSIARVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYRQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>NZ_LT992435.1|WP_000615468.1|1424750_1425482_-|amino-acid-ABC-transporter-ATP-binding-protein
MIQLNNIHKSFNDVEVIKGIDLSVGKGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEIFNNPKTEELKRFLNVINEE
>NZ_LT992435.1|WP_076686211.1|1423403_1424654_+|FemA/FemB-family-glycyltransferase-FmhA
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCLYVLIDPYLIENLRNAEGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIHWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALEESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESAEDYGVQQFKKGFNAHVEEYIGDFIKPIKPMLYKLQTYLKHKRR
>NZ_LT992435.1|WP_000819842.1|1422786_1423149_-|DUF4467-domain-containing-protein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDERVSYKQDFDSRRYYQQHDADYHEENMTN
>NZ_LT992435.1|WP_000162809.1|1422168_1422768_-|DsbA-family-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAEDHHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>NZ_LT992435.1|WP_001791249.1|1431257_1431362_-|hypothetical-protein
MLTNRLTSVNYVKKRLIQNIQRILSKKVLYGEMQ
>NZ_LT992435.1|WP_000792549.1|1431456_1432770_+|B-domain-containing-protein
MKNKYISKLLVGAATITLATMISNGEAKASENTQQSSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNKYYQYKGLIDKTVLTTIGSGYGSYIKPLEVSKESGNLAKSYAQVRNYVTESINTGKVLYAFYQKPELVKTAIKAQETATTFKNALTGIFKSFWK
>NZ_LT992435.1|WP_000594516.1|1433305_1434235_+|bi-component-gamma-hemolysin-HlgAB-subunit-A
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHEKGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>NZ_LT992435.1|WP_000916696.1|1434802_1435750_+|bi-component-gamma-hemolysin-HlgCB-subunit-C
MLKNKILATTLSVSLLAPLANPLLEKAKAANDTEDIGKGNDVEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKNTNHIKSMRWPFQYNIGLKTNDPNVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFVTASGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRIHNAFKNRNYTVKYEVNWKTHEIKVKGQN
>NZ_LT992435.1|WP_001056918.1|1435751_1436729_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MNMNKLVKSSVATSMALLLLSNTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKAAGNINSGYERPNPKDYDFSKIYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNYKTRTFKSTYEIDWENHKVKLLDTKETEINK
>NZ_LT992435.1|WP_000200952.1|1436787_1437255_-|QueT-transporter-family-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSVLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLILSVILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NZ_LT992435.1|WP_000286884.1|1437265_1437958_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQNLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYETV
>NZ_LT992435.1|WP_000971558.1|1437968_1439084_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKTVGYIDRQYIEVENQRCTNYTSNDYLGLGQIAFDKNDFEKFMRKYSYHLSSSRLISGSSAAYEEIETMLAGWLGYSACTILNSGYDANLTLFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAECPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKSLNVNYNSSNSPIKFIEFDDIEAAENIHQILLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NZ_LT992435.1|WP_001046647.1|1439061_1440069_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYGTCENKENKNDVSRAN
>NZ_LT992435.1|WP_001110067.1|1440070_1441429_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKCKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRNCKENGLMIRNLENVITFVPLLSMSNKEVKTMVRIFKKAVHNILDRKC

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Crispr_ID: NZ_LT992435_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT992435_3

2437181-2437282

Orphan

Consensus_repeat	Method
CATAAGAGCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LT992435_3

>merge|NZ_LT992435|3|2437181-2437282|CRISPRCasFinder
CATAAGAGCCCCTAATTAATAAATTAAAAGGGGACAAAGGAATACAGTTGGATGCTAACGCACCAACTGCATAAGAACCCCTAATTAATAAATTAAAAGGGG

>NZ_LT992435|3|3|2437181-2437282|CRISPRCasFinder
CATAAGAGCCCCTAATTAATAAATTAAAAGGGG	ACAAAGGAATACAGTTGGATGCTAACGCACCAACTG
CATAAGAACCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT992435.1\|WP_000842865.1\|2439103_2439793_-\|DUF1129-family-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_000733438.1\|2440430_2440820_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
NZ_LT992435.1\|WP_000367064.1\|2437299_2438520_+\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|341024
NZ_LT992435.1\|WP_000820900.1\|2441973_2442540_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_LT992435.1\|WP_000120368.1\|2426901_2427909_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541
NZ_LT992435.1\|WP_000532969.1\|2433838_2434555_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_LT992435.1\|WP_000865625.1\|2435380_2436025_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_LT992435.1\|WP_001259685.1\|2439920_2440364_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LT992435.1\|WP_001805574.1\|2433289_2433649_+\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
NZ_LT992435.1\|WP_000731644.1\|2428494_2429292_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_LT992435.1\|WP_000152582.1\|2438516_2439005_+\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_LT992435.1\|WP_000148819.1\|2442541_2443000_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_LT992435.1\|WP_000081596.1\|2429652_2430297_+\|Bax-inhibitor-1-family-protein	unknown	unknown	gnl\|CDD\|223742
NZ_LT992435.1\|WP_000638623.1\|2441336_2441879_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_LT992435.1\|WP_000687415.1\|2436140_2437007_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_LT992435.1\|WP_115657113.1\|2443002_2443686_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
NZ_LT992435.1\|WP_115657112.1\|2430993_2433144_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_LT992435.1\|WP_000844823.1\|2434554_2435028_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226072
NZ_LT992435.1\|WP_000545116.1\|2440957_2441257_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LT992435.1\|WP_001806154.1\|2435119_2435236_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LT992435.1\|WP_000733438.1\|2440430_2440820_+\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000121797
NZ_LT992435.1\|WP_000367064.1\|2437299_2438520_+\|sugar-efflux-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.37741e-101
NZ_LT992435.1\|WP_000820900.1\|2441973_2442540_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.34406e-61
NZ_LT992435.1\|WP_000120368.1\|2426901_2427909_+\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	5.23541e-104
NZ_LT992435.1\|WP_000532969.1\|2433838_2434555_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	1.24759e-136
NZ_LT992435.1\|WP_001805574.1\|2433289_2433649_+\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.80838e-22
NZ_LT992435.1\|WP_000865625.1\|2435380_2436025_+\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	1.86772e-90
NZ_LT992435.1\|WP_000081596.1\|2429652_2430297_+\|Bax-inhibitor-1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	6.05655e-32
NZ_LT992435.1\|WP_001259685.1\|2439920_2440364_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	7.52512e-12
NZ_LT992435.1\|WP_000731644.1\|2428494_2429292_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.27934e-40
NZ_LT992435.1\|WP_000148819.1\|2442541_2443000_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.78289e-77
NZ_LT992435.1\|WP_000638623.1\|2441336_2441879_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.74611e-27
NZ_LT992435.1\|WP_000687415.1\|2436140_2437007_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	7.62776e-39
NZ_LT992435.1\|WP_115657113.1\|2443002_2443686_-\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000390965
NZ_LT992435.1\|WP_000152582.1\|2438516_2439005_+\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
NZ_LT992435.1\|WP_115657112.1\|2430993_2433144_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	1.66296e-20
NZ_LT992435.1\|WP_000844823.1\|2434554_2435028_+\|cupin-domain-containing-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	3.31269e-71

>NZ_LT992435.1|WP_000687415.1|2436140_2437007_+|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISREQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVERPKA
>NZ_LT992435.1|WP_000865625.1|2435380_2436025_+|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNRQKPQNKTNFEKSKQIKPKQYNQTKNHQQQKKN
>NZ_LT992435.1|WP_001806154.1|2435119_2435236_+|hypothetical-protein
MLQLFLMKLTLNGFENDKTIIFIFLKNHFYEEMCVLSN
>NZ_LT992435.1|WP_000844823.1|2434554_2435028_+|cupin-domain-containing-protein
MKTAKQWINELQLESHPEGGFYRETIREVLKDGHRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGAYTTATLGTDIQNGDVLQYVVPKGTIFASSIENLNSYSLVGCMCQPAFEFKQFELFKQSELFVQYPHLKSVIEKYALK
>NZ_LT992435.1|WP_000532969.1|2433838_2434555_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKTVDDILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEEDQVTFEKLIDALEDLEDVQNVFHNVDLK
>NZ_LT992435.1|WP_001805574.1|2433289_2433649_+|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKYCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI
>NZ_LT992435.1|WP_115657112.1|2430993_2433144_+|helix-turn-helix-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPINDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKFNKCIMLNPEPLVGGMAQEVKEVILNYIDHYKNHLTDVIHIDEDKFEIPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYYVEEAFMNVIRQLSPNEINHHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFDKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQTFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIQSETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSNNSLNINVTFNALYIIKIGKK
>NZ_LT992435.1|WP_000081596.1|2429652_2430297_+|Bax-inhibitor-1-family-protein
MSQNTNHSYFQQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>NZ_LT992435.1|WP_000731644.1|2428494_2429292_-|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>NZ_LT992435.1|WP_000120368.1|2426901_2427909_+|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLFF
>NZ_LT992435.1|WP_000367064.1|2437299_2438520_+|sugar-efflux-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>NZ_LT992435.1|WP_000152582.1|2438516_2439005_+|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>NZ_LT992435.1|WP_000842865.1|2439103_2439793_-|DUF1129-family-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKSGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>NZ_LT992435.1|WP_001259685.1|2439920_2440364_+|GNAT-family-N-acetyltransferase
MRTLNKDEHNYIKQIASIHETLLSQSESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKQISSTIHKSNLPMISLNKDLGYQVSHVKMYKDID
>NZ_LT992435.1|WP_000733438.1|2440430_2440820_+|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDNKKDEDKDKEASQDKQPKDQTKSSNKDNHKKPTSTDKDQKANDKHQP
>NZ_LT992435.1|WP_000545116.1|2440957_2441257_+|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>NZ_LT992435.1|WP_000638623.1|2441336_2441879_+|GNAT-family-N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNATYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSEYPFKELPLYEIGWRLLPEFWGKGLATEGANATLKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>NZ_LT992435.1|WP_000820900.1|2441973_2442540_-|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYNLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>NZ_LT992435.1|WP_000148819.1|2442541_2443000_-|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVITQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYINAQIRKQGGRHKGPPPFTKQDQKVFEQSLLRVIHRIKELD
>NZ_LT992435.1|WP_115657113.1|2443002_2443686_-|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKKEQKAREKNEIQRIKDMKKTQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA

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Crispr_ID: NZ_LT992435_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LT992435_4

2647047-2647192

Orphan

Consensus_repeat	Method
CAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGCCAG	PILER-CR

2 spacers

The CRISPR arrays of NZ_LT992435_4

>merge|NZ_LT992435|4|2647047-2647192|PILER-CR
CGGGGCCCCAACACAGAGAAATTTAGGAGCCAATTTCTACAGACAATACAAGTTGGCGGGGCCCCAACACAGAAGCTGGCGAAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGTGGAAAGCCAG

>NZ_LT992435|4|1|2647047-2647192|PILER-CR
CGGGGCCCCAACACAGAGAAATTTAGGAGCCAATTTCTACAGAC	AATACAAGTTGGCGGGGCCCCAACACAGA
AGCTGGCGAAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGG	CCCCAACACAGAAG
CTGGTGGAAAGCCAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LT992435.1\|WP_000167314.1\|2644378_2645569_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
NZ_LT992435.1\|WP_001081626.1\|2637792_2638221_-\|Na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
NZ_LT992435.1\|WP_001067294.1\|2642205_2642583_+\|S1-RNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224023
NZ_LT992435.1\|WP_000185324.1\|2647426_2648356_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|176543
NZ_LT992435.1\|WP_000670752.1\|2662930_2663833_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_LT992435.1\|WP_000758209.1\|2654359_2654884_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_LT992435.1\|WP_000172361.1\|2655634_2659111_+\|helicase-exonuclease-AddAB-subunit-AddB	unknown	unknown	gnl\|CDD\|213736
NZ_LT992435.1\|WP_000007965.1\|2653779_2654355_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_LT992435.1\|WP_000035064.1\|2641196_2641790_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|238908
NZ_LT992435.1\|WP_000781162.1\|2640749_2641133_-\|kinase-associated-lipoprotein-B	unknown	unknown	gnl\|CDD\|378054
NZ_LT992435.1\|WP_000138487.1\|2645677_2646922_+\|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
NZ_LT992435.1\|WP_000148855.1\|2651522_2652854_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
NZ_LT992435.1\|WP_000154909.1\|2659111_2662765_+\|helicase-exonuclease-AddAB-subunit-AddA	unknown	unknown	gnl\|CDD\|274299
NZ_LT992435.1\|WP_000838022.1\|2642943_2644071_+\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_LT992435.1\|WP_000711897.1\|2654899_2655475_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_LT992435.1\|WP_000054618.1\|2638213_2640619_-\|Na+/H+-antiporter-subunit-A	unknown	unknown	gnl\|CDD\|237155
NZ_LT992435.1\|WP_000573077.1\|2635962_2637459_-\|Na+/H+-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
NZ_LT992435.1\|WP_000066054.1\|2648597_2649977_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
NZ_LT992435.1\|WP_000660057.1\|2649966_2651172_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
NZ_LT992435.1\|WP_000402803.1\|2637451_2637793_-\|Na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497

Protein	Function_ID	Function_description	E-value
NZ_LT992435.1\|WP_000167314.1\|2644378_2645569_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
NZ_LT992435.1\|WP_001081626.1\|2637792_2638221_-\|Na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
NZ_LT992435.1\|WP_001067294.1\|2642205_2642583_+\|S1-RNA-binding-domain-containing-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
NZ_LT992435.1\|WP_000185324.1\|2647426_2648356_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	7.97991e-151
NZ_LT992435.1\|WP_000670752.1\|2662930_2663833_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.0042e-87
NZ_LT992435.1\|WP_000758209.1\|2654359_2654884_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.81012e-49
NZ_LT992435.1\|WP_000172361.1\|2655634_2659111_+\|helicase-exonuclease-AddAB-subunit-AddB	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LT992435.1\|WP_000007965.1\|2653779_2654355_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.15479e-40
NZ_LT992435.1\|WP_000035064.1\|2641196_2641790_+\|peptidylprolyl-isomerase	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	2.08824e-65
NZ_LT992435.1\|WP_000781162.1\|2640749_2641133_-\|kinase-associated-lipoprotein-B	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
NZ_LT992435.1\|WP_000138487.1\|2645677_2646922_+\|Glu/Leu/Phe/Val-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NZ_LT992435.1\|WP_000148855.1\|2651522_2652854_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
NZ_LT992435.1\|WP_000154909.1\|2659111_2662765_+\|helicase-exonuclease-AddAB-subunit-AddA	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LT992435.1\|WP_000838022.1\|2642943_2644071_+\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
NZ_LT992435.1\|WP_000711897.1\|2654899_2655475_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
NZ_LT992435.1\|WP_000054618.1\|2638213_2640619_-\|Na+/H+-antiporter-subunit-A	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
NZ_LT992435.1\|WP_000573077.1\|2635962_2637459_-\|Na+/H+-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
NZ_LT992435.1\|WP_000066054.1\|2648597_2649977_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
NZ_LT992435.1\|WP_000660057.1\|2649966_2651172_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NZ_LT992435.1\|WP_000402803.1\|2637451_2637793_-\|Na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	9.82501e-64

>NZ_LT992435.1|WP_000138487.1|2645677_2646922_+|Glu/Leu/Phe/Val-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>NZ_LT992435.1|WP_000167314.1|2644378_2645569_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>NZ_LT992435.1|WP_000838022.1|2642943_2644071_+|NADH-dependent-flavin-oxidoreductase
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTAQEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPIAVIEEVLKAKEMYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>NZ_LT992435.1|WP_001067294.1|2642205_2642583_+|S1-RNA-binding-domain-containing-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>NZ_LT992435.1|WP_000035064.1|2641196_2641790_+|peptidylprolyl-isomerase
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYNGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>NZ_LT992435.1|WP_000781162.1|2640749_2641133_-|kinase-associated-lipoprotein-B
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>NZ_LT992435.1|WP_000054618.1|2638213_2640619_-|Na+/H+-antiporter-subunit-A
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLALPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDILGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPDKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>NZ_LT992435.1|WP_001081626.1|2637792_2638221_-|Na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>NZ_LT992435.1|WP_000402803.1|2637451_2637793_-|Na(+)/H(+)-antiporter-subunit-C
MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>NZ_LT992435.1|WP_000573077.1|2635962_2637459_-|Na+/H+-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>NZ_LT992435.1|WP_000185324.1|2647426_2648356_-|glycerophosphodiester-phosphodiesterase
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKRHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>NZ_LT992435.1|WP_000066054.1|2648597_2649977_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDSDIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>NZ_LT992435.1|WP_000660057.1|2649966_2651172_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYQKALDMGAIECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFVKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGNSNEQ
>NZ_LT992435.1|WP_000148855.1|2651522_2652854_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>NZ_LT992435.1|WP_000007965.1|2653779_2654355_+|TVP38/TMEM64-family-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>NZ_LT992435.1|WP_000758209.1|2654359_2654884_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>NZ_LT992435.1|WP_000711897.1|2654899_2655475_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>NZ_LT992435.1|WP_000172361.1|2655634_2659111_+|helicase-exonuclease-AddAB-subunit-AddB
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKELIKYAKSVTIILTTDGNNDQFSLFRKPSEVLQHIEEIANELNISIERQYFNQFYRFNNQDLKHLEQEFDAFQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILYFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMDRFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLTQIQALFNRLEITNIPRYHEVAPLSLMQHVKQTKIALFEALRSWLDDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVQLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSAILDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQAVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>NZ_LT992435.1|WP_000154909.1|2659111_2662765_+|helicase-exonuclease-AddAB-subunit-AddA
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPDPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLATTNYIFKHMMDEQVGEVNYDESAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELALIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYRAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIVYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYRYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSKQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>NZ_LT992435.1|WP_000670752.1|2662930_2663833_+|fumarylacetoacetate-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVEKLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	30035-30048	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	130496-130509	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	350011-350024	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1267737-1267750	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1278543-1278556	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1278657-1278670	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1278717-1278730	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1313111-1313124	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1471624-1471637	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	1983161-1983174	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	2020314-2020327	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	2542273-2542286	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	2598341-2598354	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	2647193-2647206	0	1.0
NZ_LT992435_4	4.2\|2647164\|14\|NZ_LT992435\|PILER-CR	2647164-2647177	14	NZ_LT992435.1	2647249-2647262	0	1.0
NZ_LT992435_1	1.1\|1240036\|37\|NZ_LT992435\|CRISPRCasFinder	1240036-1240072	37	NZ_LT992435.1	1239947-1239983	2	0.946

1. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 30035-30048, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

2. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 130496-130509, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

3. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 350011-350024, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

4. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1267737-1267750, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

5. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1278543-1278556, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

6. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1278657-1278670, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

7. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1278717-1278730, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

8. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1313111-1313124, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

9. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1471624-1471637, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

10. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 1983161-1983174, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

11. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 2020314-2020327, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

12. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 2542273-2542286, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

13. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 2598341-2598354, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

14. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 2647193-2647206, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

15. spacer 4.2|2647164|14|NZ_LT992435|PILER-CR matches to position: 2647249-2647262, mismatch: 0, identity: 1.0

cttacaataatgtg	CRISPR spacer
cttacaataatgtg	Protospacer
**************

16. spacer 1.1|1240036|37|NZ_LT992435|CRISPRCasFinder matches to position: 1239947-1239983, mismatch: 2, identity: 0.946

agctcacaaaacccttgatatcattggtttcccatga	CRISPR spacer
agctcacaaaacccttgatatcactggtttctcatga	Protospacer
***********************.*******.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31716 : 40189

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001622461.1\|31716_32199_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.0e-22	44.7
WP_001010404.1\|32185_33310_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174048.1\|33313_34018_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	4.0e-46	41.2
WP_000848350.1\|34017_34281_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_115657031.1\|34282_34954_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032752.1\|34946_37136_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000483713.1\|37114_38599_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030827.1\|38591_39620_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.2e-62	41.7
WP_000238657.1\|39622_40189_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	8.0e-29	39.6

DBSCAN-SWA_2

295550 : 308537

Staphylococcus_phage(60.0%)

integrase,portal,terminase

attL 289373:289390|attR 312843:312860

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
289373:289390	attL	NA	NA	NA	NA
WP_000146714.1\|295550_296258_-\|integrase	phage integrase SAM-like domain-containing protein	V9QKF1	Oenococcus_phage	4.7e-10	26.2
WP_001183755.1\|296310_297006_-	Ltp family lipoprotein	A0A2H4J5B8	uncultured_Caudovirales_phage	2.1e-07	51.5
WP_000554409.1\|297017_297401_-	hypothetical protein	NA	NA	NA	NA
WP_001083979.1\|297547_297913_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	1.8e-21	47.9
WP_000842951.1\|298074_298287_+	DUF739 family protein	A0A2I6PDH8	Staphylococcus_phage	6.8e-26	83.3
WP_000789021.1\|298334_298616_+	hypothetical protein	NA	NA	NA	NA
WP_000072840.1\|298786_298948_+	DUF1270 family protein	R4IH12	Staphylococcus_phage	1.1e-12	69.8
WP_000786995.1\|299034_299352_+	DUF2482 family protein	W5RAK4	Staphylococcus_phage	1.6e-39	80.6
WP_000786635.1\|299341_299608_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	3.9e-18	53.6
WP_001004328.1\|299612_300149_+	host-nuclease inhibitor Gam family protein	A0A0H3U480	Staphylococcus_phage	1.1e-75	81.4
WP_000818736.1\|300149_300929_+	ATP-binding protein	A0A1W6JPW0	Staphylococcus_phage	9.3e-129	88.8
WP_000702008.1\|300955_301504_+	hypothetical protein	A7TWM8	Staphylococcus_phage	1.7e-92	92.9
WP_000929467.1\|301517_302456_+	DnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	4.8e-47	48.1
WP_000945229.1\|302456_302747_+	hypothetical protein	A0A223LIA9	Staphylococcus_phage	5.5e-18	58.1
WP_000714365.1\|302761_302920_+	hypothetical protein	A0A0E3T9L7	Staphylococcus_phage	7.9e-19	90.4
WP_000860977.1\|302925_303237_+	hypothetical protein	NA	NA	NA	NA
WP_000185174.1\|303229_303760_+	nucleotide pyrophosphohydrolase	A0A1P8VVP1	Streptococcus_phage	8.0e-23	39.1
WP_025174108.1\|303901_304009_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	1.4e-06	84.4
WP_000835356.1\|304005_304470_+	hypothetical protein	C9E2P0	Enterococcus_phage	2.5e-20	43.7
WP_000653928.1\|304746_305235_+	hypothetical protein	R9TMH4	Paenibacillus_phage	1.9e-07	27.7
WP_000090969.1\|305386_305815_+	helix-turn-helix domain-containing protein	A1EAE0	Streptococcus_phage	1.1e-25	45.1
WP_000207540.1\|305801_307076_+\|terminase	PBSX family phage terminase large subunit	Q4ZE37	Staphylococcus_virus	4.2e-195	76.4
WP_000158569.1\|307088_308537_+\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	1.9e-196	69.6
312843:312860	attR	NA	NA	NA	NA

DBSCAN-SWA_3

594721 : 603033

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|594721_595507_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924214.1\|595632_596523_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
WP_001062177.1\|596532_597879_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683915.1\|597992_599093_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	3.0e-08	30.6
WP_000624564.1\|599095_599773_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|599903_601010_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217237.1\|601233_603033_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.3e-53	36.0

DBSCAN-SWA_4

672347 : 681391

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364543.1\|672347_672866_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	2.1e-28	45.8
WP_000594987.1\|672887_675161_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	7.3e-65	29.5
WP_115657062.1\|675364_677644_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|677918_678179_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|678197_679337_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_031928192.1\|679359_680385_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005764.1\|680386_681391_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_5

804775 : 851104

Staphylococcus_phage(91.43%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_115657064.1\|804775_811333_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	6.6e-292	87.5
WP_000836464.1\|811657_811969_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	6.9e-51	97.1
WP_001622206.1\|811990_814408_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.7
WP_001025064.1\|814696_815878_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	9.6e-218	99.7
WP_000526542.1\|815987_816941_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764418.1\|816937_817501_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	4.1e-102	98.4
WP_000757543.1\|817617_818019_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|818589_819417_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_014937042.1\|819419_819539_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|819650_820652_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|820773_821238_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159030.1\|821250_822432_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
WP_000493880.1\|822442_823075_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.1e-110	97.6
WP_000077348.1\|823081_824125_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.2e-195	98.8
WP_001261660.1\|824606_826109_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	2.3e-30	100.0
WP_000221174.1\|826751_827066_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	1.8e-51	96.2
WP_076686008.1\|827065_828358_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	4.0e-217	94.7
WP_001032834.1\|828444_829299_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|829573_829798_-	hypothetical protein	NA	NA	NA	NA
WP_000671060.1\|829996_830467_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	3.8e-69	85.2
WP_001152694.1\|830579_831023_+	competence protein ComK	NA	NA	NA	NA
WP_001030473.1\|831009_831453_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	1.1e-49	77.9
WP_001168913.1\|831749_832385_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000492904.1\|832551_833172_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001096494.1\|833907_834621_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091443.1\|834879_835182_+	hypothetical protein	NA	NA	NA	NA
WP_001200545.1\|835437_835803_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.2e-59	99.2
WP_000623468.1\|835799_836153_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.7e-19	91.5
WP_000453324.1\|836402_837236_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.5e-158	99.3
WP_000366165.1\|837447_838356_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
WP_000933821.1\|838480_839674_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000109912.1\|840045_841638_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_001827685.1\|842017_842764_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	6.6e-140	97.6
WP_000672013.1\|842768_843242_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718111.1\|843307_843565_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.0e-44	97.6
WP_000778530.1\|843561_844563_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	3.1e-185	97.6
WP_000348383.1\|844567_846046_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.0e-277	95.1
WP_072468941.1\|846204_846660_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	2.3e-79	98.6
WP_001796416.1\|846962_847613_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	1.3e-30	70.4
WP_000070666.1\|847693_848689_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	1.9e-73	97.2
WP_000669031.1\|848764_849391_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.9e-85	84.1
WP_000627532.1\|849431_849773_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	4.8e-53	91.2
WP_098686295.1\|849974_851104_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	5.2e-80	54.3

DBSCAN-SWA_6

943627 : 1037622

114

Staphylococcus_phage(87.18%)

protease,tail,holin,head,capsid,tRNA,portal,terminase,integrase

attL 1004474:1004491|attR 1028820:1028837

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000027926.1\|943627_945085_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_000170162.1\|945086_945389_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000957019.1\|945755_947294_+	sodium/proline symporter PutP	NA	NA	NA	NA
WP_000831695.1\|947382_948582_-	CamS family sex pheromone protein	NA	NA	NA	NA
WP_115657067.1\|948594_950598_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	3.4e-114	36.1
WP_000992924.1\|950601_952794_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-135	42.2
WP_000272062.1\|952790_953483_-	heptaprenylglyceryl phosphate synthase	NA	NA	NA	NA
WP_001165363.1\|953654_953957_-	hypothetical protein	NA	NA	NA	NA
WP_076686095.1\|954065_955361_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	1.6e-16	32.9
WP_000827739.1\|956207_957374_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434537.1\|957404_957731_+	staphostatin A	NA	NA	NA	NA
WP_000669865.1\|958021_958195_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|958175_958778_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000164017.1\|959048_959870_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	4.4e-68	52.7
WP_000284427.1\|959862_961332_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.2e-106	44.3
WP_000898869.1\|961515_962592_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177820.1\|962611_963406_+	prephenate dehydratase	NA	NA	NA	NA
WP_031785526.1\|963477_963585_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1\|963595_965158_-	SLC13 family permease	NA	NA	NA	NA
WP_000275721.1\|965362_966460_-	pectate lyase	U5PWM6	Bacillus_phage	2.5e-47	34.6
WP_000149686.1\|966831_967392_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|967444_968374_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|968566_968740_-	hypothetical protein	NA	NA	NA	NA
WP_001021226.1\|968791_970171_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181320.1\|970290_971319_-	lactonase family protein	NA	NA	NA	NA
WP_000205103.1\|971588_971990_+	YolD-like family protein	U3PG23	Staphylococcus_phage	1.3e-22	42.9
WP_000267034.1\|972046_972220_-	hypothetical protein	NA	NA	NA	NA
WP_001188080.1\|972670_973711_+	choloylglycine hydrolase	NA	NA	NA	NA
WP_000713063.1\|973767_974610_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033966.1\|974606_975164_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966286.1\|975223_975748_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|975868_976432_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221648.1\|976497_977238_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|977237_978110_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645721.1\|978106_978787_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991300.1\|978787_979684_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|979680_980061_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681966.1\|980318_980495_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|980736_980835_-	hypothetical protein	NA	NA	NA	NA
WP_001068518.1\|981034_982321_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000669710.1\|982591_984661_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669789.1\|985618_985798_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1\|986108_986369_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|986421_986772_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000727649.1\|987456_987906_+	chemotaxis-inhibiting protein CHIPS	A0A1P8L6A8	Staphylococcus_phage	1.1e-78	100.0
WP_000919350.1\|988985_989477_-	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
WP_000861038.1\|989667_990423_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611512.1\|990434_990689_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_001791821.1\|990740_990848_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|990900_991077_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000539688.1\|991226_991523_-	DUF2951 domain-containing protein	D2JLG2	Staphylococcus_phage	2.9e-46	100.0
WP_001040261.1\|991580_991868_-	hypothetical protein	D2JLG1	Staphylococcus_phage	1.3e-43	100.0
WP_001153681.1\|991914_992067_-	hypothetical protein	D2JLG0	Staphylococcus_phage	5.2e-20	100.0
WP_000582165.1\|992056_995842_-	hypothetical protein	A0A1X9H0H3	Staphylococcus_phage	0.0e+00	98.5
WP_000567408.1\|995857_997342_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
WP_001796452.1\|997338_1001868_-\|tail	phage tail tape measure protein	A0A2I6PDK2	Staphylococcus_phage	0.0e+00	99.8
WP_001789580.1\|1001924_1002086_-	hypothetical protein	A0A0H3U330	Staphylococcus_phage	1.6e-22	100.0
WP_001096355.1\|1002112_1002463_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_071621395.1\|1002512_1002737_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_000268733.1\|1002778_1003423_-\|tail	phage tail protein	A0A1X9H0J2	Staphylococcus_phage	1.5e-119	100.0
WP_000565498.1\|1003423_1003831_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114227.1\|1003827_1004232_-	HK97 gp10 family phage protein	G4KNQ5	Staphylococcus_phage	2.1e-68	99.3
WP_000755150.1\|1004228_1004591_-\|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
1004474:1004491	attL	NA	NA	NA	NA
WP_000150936.1\|1004574_1004859_-\|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1\|1004848_1005133_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1\|1005152_1006298_-\|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1\|1006321_1007059_-\|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025274.1\|1007042_1008230_-\|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1\|1008245_1009907_-\|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1\|1009903_1010248_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988336.1\|1010378_1010678_-	HNH endonuclease	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
WP_000590122.1\|1010909_1011326_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_001622114.1\|1011353_1011554_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	4.0e-28	98.5
WP_000595265.1\|1011553_1011703_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000592207.1\|1011699_1012086_-	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
WP_076686084.1\|1012082_1012289_-	DUF1381 domain-containing protein	A0A0H3U2R7	Staphylococcus_phage	4.9e-29	98.5
WP_001282074.1\|1012285_1012531_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_001066447.1\|1012567_1013104_-	dUTP diphosphatase	A0A0H3U2Z8	Staphylococcus_phage	7.2e-96	100.0
WP_000714403.1\|1013096_1013267_-	hypothetical protein	A0A0H3U4U6	Staphylococcus_phage	8.2e-22	100.0
WP_001065097.1\|1013253_1013508_-	DUF1024 family protein	A0A0H3U469	Staphylococcus_phage	5.0e-39	100.0
WP_000131370.1\|1013522_1013765_-	hypothetical protein	Q4ZDP7	Staphylococcus_virus	2.1e-39	95.0
WP_000101288.1\|1013768_1014137_-	hypothetical protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
WP_000401960.1\|1014149_1014554_-	RusA family crossover junction endodeoxyribonuclease	A0EWX6	Staphylococcus_phage	1.9e-72	100.0
WP_000338530.1\|1014562_1014781_-	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
WP_115657068.1\|1014787_1015681_-	DnaD domain-containing protein	A0A2I6PDG7	Staphylococcus_phage	2.1e-140	99.0
WP_115657069.1\|1015710_1016181_-	single-stranded DNA-binding protein	A0EWX3	Staphylococcus_phage	4.8e-80	98.1
WP_073394849.1\|1016181_1016799_-	MBL fold metallo-hydrolase	A0A2I6PDI9	Staphylococcus_phage	9.1e-87	100.0
WP_000138475.1\|1016879_1017800_-	recombinase RecT	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_000700555.1\|1017801_1019745_-	AAA family ATPase	S4V9K6	Staphylococcus_phage	0.0e+00	100.0
WP_001205732.1\|1019753_1020017_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291510.1\|1020025_1020286_-	DUF1108 family protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
WP_000165371.1\|1020290_1020593_-	DUF2482 family protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
WP_000048129.1\|1020687_1020849_-	DUF1270 family protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
WP_001120201.1\|1020845_1021169_-	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
WP_000762519.1\|1021223_1021604_+	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	3.4e-68	99.2
WP_001148862.1\|1021590_1021788_-	hypothetical protein	O80075	Staphylococcus_phage	3.5e-24	87.7
WP_001148605.1\|1021803_1022556_-	phage antirepressor KilAC domain-containing protein	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
WP_000128907.1\|1022606_1022936_+	hypothetical protein	M9NS98	Staphylococcus_phage	2.7e-53	100.0
WP_001025404.1\|1022924_1023140_-	DUF2829 domain-containing protein	A0A0H3U4C7	Staphylococcus_phage	4.8e-35	100.0
WP_000854074.1\|1023136_1023418_-	helix-turn-helix transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	4.6e-38	96.5
WP_001801500.1\|1023414_1023588_-	hypothetical protein	NA	NA	NA	NA
WP_001031454.1\|1023550_1024264_+	helix-turn-helix transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
WP_000759682.1\|1024279_1025212_+	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
WP_000591749.1\|1025217_1025559_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
WP_000705248.1\|1025762_1025945_+	hypothetical protein	M9NSW6	Staphylococcus_phage	4.1e-27	100.0
WP_000825947.1\|1026044_1026509_+	hypothetical protein	A0EWV3	Staphylococcus_phage	1.1e-28	100.0
WP_000857191.1\|1026567_1027605_+\|integrase	site-specific integrase	A0EWV2	Staphylococcus_phage	9.1e-180	100.0
WP_000595616.1\|1028742_1029762_-	leukocidin/hemolysin toxin family protein	A0A2I6PEU3	Staphylococcus_phage	2.6e-54	39.8
1028820:1028837	attR	NA	NA	NA	NA
WP_000791399.1\|1029783_1030839_-	succinyl-diaminopimelate desuccinylase	A0A2I6PER8	Staphylococcus_phage	6.0e-38	34.6
WP_000206615.1\|1031269_1032493_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_115657070.1\|1032888_1034196_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000240642.1\|1034727_1036344_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|1036419_1036704_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000197627.1\|1036878_1037622_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

2468250 : 2476069

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|2468250_2469306_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|2469305_2469992_-	response regulator transcription factor	NA	NA	NA	NA
WP_076686191.1\|2469966_2470440_-	DoxX family protein	NA	NA	NA	NA
WP_001093554.1\|2470780_2471221_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637683.1\|2471500_2472085_-	hypothetical protein	NA	NA	NA	NA
WP_001062976.1\|2472183_2472897_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|2472900_2473320_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446726.1\|2473321_2473990_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.4e-66	57.5
WP_000604517.1\|2474340_2474934_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	8.9e-39	44.0
WP_001217805.1\|2474917_2476069_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_8

2488040 : 2502316

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663021.1\|2488040_2489099_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	2.6e-20	26.9
WP_000197263.1\|2489256_2489805_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429016.1\|2490492_2491410_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.4
WP_031785486.1\|2491500_2491602_+	hypothetical protein	NA	NA	NA	NA
WP_000193753.1\|2491679_2493185_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.6e-58	32.2
WP_000930014.1\|2493525_2494026_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|2494045_2494912_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|2495713_2496112_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_064131610.1\|2496074_2498180_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562500.1\|2498297_2499269_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	3.2e-171	91.3
WP_000876313.1\|2499643_2500615_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.0e-140	79.9
WP_001245581.1\|2500601_2501558_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616861.1\|2501554_2502316_+	ATP-binding cassette domain-containing protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	2.7e-16	30.6

DBSCAN-SWA_9

2554520 : 2575021

Staphylococcus_phage(66.67%)

coat,integrase,transposase

attL 2557182:2557197|attR 2573209:2573224

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_115657119.1\|2554520_2556893_+	ribonuclease R	Q0GXV6	Lactococcus_phage	9.6e-92	38.7
WP_001085185.1\|2556914_2557379_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
2557182:2557197	attL	NA	NA	NA	NA
WP_000149511.1\|2557941_2559048_-\|integrase	site-specific integrase	H0UST3	Bacillus_phage	1.1e-77	44.4
WP_000358990.1\|2559037_2559841_-	helix-turn-helix transcriptional regulator	A0A2H4JC02	uncultured_Caudovirales_phage	5.3e-10	55.9
WP_001045296.1\|2559976_2560180_+	transcriptional regulator	NA	NA	NA	NA
WP_000163544.1\|2560215_2560434_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000784885.1\|2560445_2560592_+	hypothetical protein	NA	NA	NA	NA
WP_001058494.1\|2560584_2560794_+	hypothetical protein	Q4ZE76	Staphylococcus_phage	8.5e-29	94.2
WP_001103939.1\|2560796_2561114_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	3.2e-19	57.0
WP_001002717.1\|2561177_2562047_+	primase C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	8.7e-160	95.8
WP_111125118.1\|2562063_2562588_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	8.9e-83	98.1
WP_115657120.1\|2562599_2563728_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	5.2e-80	54.3
WP_001039170.1\|2565047_2565410_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	3.4e-65	98.3
WP_000998185.1\|2565411_2565696_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	7.7e-49	98.9
WP_001019808.1\|2565692_2566334_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	1.9e-111	92.5
WP_001288441.1\|2567042_2567387_+	hypothetical protein	A0A1W6JQF3	Staphylococcus_phage	1.4e-57	100.0
WP_000856046.1\|2567421_2568000_+	hypothetical protein	A0A1W6JQG0	Staphylococcus_phage	7.8e-80	95.8
WP_001160678.1\|2567999_2568176_+	hypothetical protein	A0A1W6JQJ5	Staphylococcus_phage	7.7e-23	100.0
WP_000777464.1\|2568228_2568756_+\|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	1.1e-88	98.9
WP_045181470.1\|2568887_2569100_+	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-31	98.6
WP_000360021.1\|2569770_2570811_+	hypothetical protein	NA	NA	NA	NA
WP_001805416.1\|2570923_2571112_+	hypothetical protein	NA	NA	NA	NA
WP_001001286.1\|2571104_2571773_+	restriction endonuclease	A0A0A7S0U2	Clostridium_phage	4.5e-15	33.7
WP_001035612.1\|2571993_2572548_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	4.2e-59	67.2
WP_001043552.1\|2573331_2574132_+	staphylococcal enterotoxin type C2	A0A097PAT7	Streptococcus_pyogenes_phage	3.1e-50	43.4
2573209:2573224	attR	NA	NA	NA	NA
WP_000746602.1\|2574298_2575021_-	staphylococcal enterotoxin type L	A0A097PAT7	Streptococcus_pyogenes_phage	1.6e-18	29.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LT992435

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection