CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483305	Staphylococcus sciuri subsp. sciuri strain NCTC12103 chromosome 1	3 crisprs	csa3,cas3,DEDDh,DinG,WYL	6	0	9	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483305_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483305_1

420704-420792

Orphan

Consensus_repeat	Method
ATATTAATATGTGTAGGTATTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483305_1

>merge|NZ_LS483305|1|420704-420792|CRISPRCasFinder
ATATTAATATGTGTAGGTATTGCTTTAAGAGCGATTACAGGCGTGTCTTGGTTATATGTCGGTACGATATTAATAGGTGTAGGTATTGC

>NZ_LS483305|1|1|420704-420792|CRISPRCasFinder
ATATTAATATGTGTAGGTATTGC	TTTAAGAGCGATTACAGGCGTGTCTTGGTTATATGTCGGTACG
ATATTAATAGGTGTAGGTATTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483305.1\|WP_048540747.1\|418502_418802_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483305.1\|WP_048540800.1\|413395_414127_+\|epoxyqueuosine-reductase-QueH	unknown	unknown	gnl\|CDD\|224551
NZ_LS483305.1\|WP_048540759.1\|425427_425988_+\|serine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|226075
NZ_LS483305.1\|WP_048540738.1\|415109_416003_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|226383
NZ_LS483305.1\|WP_048540742.1\|416804_417380_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NZ_LS483305.1\|WP_048540768.1\|431593_432799_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143479
NZ_LS483305.1\|WP_048540763.1\|427418_427931_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483305.1\|WP_025906924.1\|432868_433471_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NZ_LS483305.1\|WP_048540735.1\|411375_413292_+\|PTS-sugar-transporter-subunit-IIBCA	unknown	unknown	gnl\|CDD\|131051
NZ_LS483305.1\|WP_048540740.1\|416060_416753_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LS483305.1\|WP_048540755.1\|423862_424780_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182713
NZ_LS483305.1\|WP_048540745.1\|417542_418457_+\|LytR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|181811
NZ_LS483305.1\|WP_048540767.1\|430280_431492_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NZ_LS483305.1\|WP_048540765.1\|428164_429778_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_LS483305.1\|WP_048540761.1\|426067_426805_-\|transglycosylase	unknown	unknown	gnl\|CDD\|369056
NZ_LS483305.1\|WP_037590547.1\|418878_419739_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|225547
NZ_LS483305.1\|WP_048540757.1\|425046_425409_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NZ_LS483305.1\|WP_048540753.1\|421848_423231_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_LS483305.1\|WP_048540737.1\|414384_415062_+\|thiaminase-II	unknown	unknown	gnl\|CDD\|381701
NZ_LS483305.1\|WP_048540748.1\|419771_420332_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380339

Protein	Function_ID	Function_description	E-value
NZ_LS483305.1\|WP_048540768.1\|431593_432799_-\|hypothetical-protein	gnl\|CDD\|143479	cd07563, Peptidase_S41_IRBP, Interphotoreceptor retinoid-binding protein; serine protease family S41. Interphotoreceptor retinoid-binding protein (IRBP) is a homolog of the S41 protease, C-terminal processing peptidase (CTPase) family. It is thought to facilitate the compartmentalization of the visual cycle that requires poorly soluble and potentially toxic retinoids to cross the aqueous subretinal space between the photoreceptors and the retinal pigment epithelium (RPE). IRBP is secreted by photoreceptors into the interphotoreceptor matrix (IPM) where it is rapidly turned over by a combination of RPE and photoreceptor endocytosis. It is the most abundant soluble protein component of the IPM, consisting of homologous modules, each repeat structure arising through the duplication (as in teleost IRBP) or quadruplication (in tetrapods) of an ancient gene, arisen in the early evolution of the vertebrate eye. IRBP has been shown to promote the release of all-trans retinol from photoreceptors and facilitates its delivery to the RPE. Conversely, IRBP can promote the release of 11-cis-retinal from the RPE, prevent its isomerization in the subretinal space, and transfer it to photoreceptors. In vivo evidence implicates IRBP as a retinoid transporter in the visual cycle, suggesting a critical role for IRBP in cone function essential for human vision. IRBP is a dominant autoimmune antigen in the eye; IRBP proteolysis analysis has proven a useful biomarker for autoimmune uveitis (AU) disorders, a major cause of blindness. This family also includes a chlamydia-secreted protein, designated chlamydia protease-like activity factor (CPAF), known to degrade host proteins, enabling Chlamydia to evade host defenses and replicate.	1.36106e-08
NZ_LS483305.1\|WP_048540800.1\|413395_414127_+\|epoxyqueuosine-reductase-QueH	gnl\|CDD\|224551	COG1636, COG1636, Uncharacterized protein conserved in bacteria [Function unknown].	6.65792e-89
NZ_LS483305.1\|WP_048540759.1\|425427_425988_+\|serine-hydrolase-family-protein	gnl\|CDD\|226075	COG3545, COG3545, Predicted esterase of the alpha/beta hydrolase fold [General function prediction only].	8.09465e-29
NZ_LS483305.1\|WP_048540738.1\|415109_416003_-\|VOC-family-protein	gnl\|CDD\|226383	COG3865, COG3865, Uncharacterized protein conserved in bacteria [Function unknown].	1.55781e-43
NZ_LS483305.1\|WP_048540742.1\|416804_417380_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.0918e-20
NZ_LS483305.1\|WP_048540737.1\|414384_415062_+\|thiaminase-II	gnl\|CDD\|381701	cd19366, TenA_C_BhTenA-like, TenA_C proteins similar to Bacillus halodurans TenA. This family of TenA proteins belongs to the TenA_C class as it has a conserved active site Cys residue; the double Glu residues identified in the active site of TenA_E from the archaeon Pyrococcus furiosus is conserved in this family. TenA_C proteins (EC 3.5.99.2) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway. This family includes Bacillus halodurans TenA which participates in a salvage pathway where the thiamine degradation product 2-methyl-4-formylamino-5-aminomethylpyrimidine (formylamino-HMP) is hydrolyzed first to amino-HMP by the YlmB protein, and the amino-HMP is then hydrolyzed by TenA to produce HMP. It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	2.83801e-128
NZ_LS483305.1\|WP_025906924.1\|432868_433471_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	6.03863e-38
NZ_LS483305.1\|WP_048540735.1\|411375_413292_+\|PTS-sugar-transporter-subunit-IIBCA	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	2.83358e-168
NZ_LS483305.1\|WP_048540740.1\|416060_416753_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	2.65577e-27
NZ_LS483305.1\|WP_048540767.1\|430280_431492_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18688e-38
NZ_LS483305.1\|WP_048540745.1\|417542_418457_+\|LytR-family-transcriptional-regulator	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	4.63763e-68
NZ_LS483305.1\|WP_048540765.1\|428164_429778_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_LS483305.1\|WP_048540761.1\|426067_426805_-\|transglycosylase	gnl\|CDD\|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	4.58448e-18
NZ_LS483305.1\|WP_037590547.1\|418878_419739_+\|phosphotransferase	gnl\|CDD\|225547	COG3001, COG3001, Uncharacterized protein conserved in bacteria [Function unknown].	4.56457e-88
NZ_LS483305.1\|WP_048540757.1\|425046_425409_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.10478e-17
NZ_LS483305.1\|WP_048540753.1\|421848_423231_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_LS483305.1\|WP_048540755.1\|423862_424780_-\|hypothetical-protein	gnl\|CDD\|182713	PRK10768, PRK10768, ribonucleoside hydrolase RihC; Provisional.	8.65525e-127
NZ_LS483305.1\|WP_048540748.1\|419771_420332_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.8238e-17

>NZ_LS483305.1|WP_048540748.1|419771_420332_-|helix-turn-helix-domain-containing-protein
MKDIHTIVAHNLSQYRTSQQLSLSKVSKLTGVSKTMLNQIENGQSNPTITTLWKIANGLHLPISDLISNKEDNINCVSKSDITPIYNDNQSVTIYPYFPFNIDKNFEMFNMILLSGAEMISEGHHNGSEEYIIVHSGILEVDINGVKHTVRQDDAIRFESDVTHTYRNIGKEDVHLTATIQYQQHK
>NZ_LS483305.1|WP_037590547.1|418878_419739_+|phosphotransferase
MNKDWQSQLPIDDIKELIPVSGGDVNEAYRIERQSGTDFLLVQHNRSEDFYAAEIAGLEAFEEAGVTAPVVKGYGQINGDAYLILSYLEEGRRGSQSELGKLVAKLHSHYQQDGKFGFHLPYHGSDITFENGWKDTWINIFVEQRLDQLRDEIVRRGLWSKDELQQFEQVRTVIIEALTEHKSKPSLLHGDLWAGNYMFLSNGEPALFDPSPLYGDREFDLGATRVFGGFTEAFYKAYDEALPLSKGANERIKFYELYLLMVHLVKFGSMYAGSVQRTMDDILNDK
>NZ_LS483305.1|WP_048540747.1|418502_418802_+|hypothetical-protein
MTSINEMKIKQNINHLIQNYGIQLLNYMSDCEREEKALLSVFDKVDDQIIKASLELLKQNNLINIRTEEIMPPNIYYHLTKDGELILQMIYKFESLNFE
>NZ_LS483305.1|WP_048540745.1|417542_418457_+|LytR-family-transcriptional-regulator
MKLTRKGKVTIIIAALVLIAGIFVTVKAININNKVYQPINKQDTKHVKEKIKNNKPISIAIFGVDSNKERESENIGERTDSIMLASINPKTKTTKLVSVPRDMAVNIPGYSSHDKVAHAYAYGGSKTAVQTLKNEFNIPIDGYITVDMDGFKKTIDALDGVNVKSNKSFTFNGTKFKAGEKVKLNGQEALDFVRSRKEAGAGDDEGRQERQRIVIEATSKKLKNNLNVNNFNELMNVAQDNITTSFNLNDTRKLITDYKSATEHFEKISIDGVNQIENDGIWYFEADKDAKQQIVKTYKNNLKS
>NZ_LS483305.1|WP_048540742.1|416804_417380_-|phosphatase-PAP2-family-protein
MKKDSKLIIYYAILLILIVSLIFTNYINPIDQYVYQFIQTETLAFRLHNYLSIISFLFSPLHSGILICILLIGLYFYNRRNLLQYFIFSFSSLFIGTALKYIIQRPRPSDLIDGYSFPSMHTLTLFVAIFLILALYNHVTVKWITAILILSMMCSRIYLSAHFFSDTVASLIIVHLVYLSVTKFMHQSSRL
>NZ_LS483305.1|WP_048540740.1|416060_416753_-|GNAT-family-N-acetyltransferase
MRYNTFNQPIGDEIESFKEPNMPSIDMIEGKYSKLEHLNESHIDQLFALLCSSENDANWTYLPHEPIHDKASFTLLIEERIISKDPYFFAIVDKETHQALGIMSLLRINPKASTIEVGHIHYSSLLKRTRIATEVQYLLAQYVFETLKYRRYEWKCDSYNAPSKHAAERLGFKYEGTFRQALVYKGRNRDTNWFSIIDTEWPSIKKHYEEWLDESNFNHDGTQINKLSMN
>NZ_LS483305.1|WP_048540738.1|415109_416003_-|VOC-family-protein
MNNQRIVPHLWFDNEAQEAVDYYMQTFPESEIISDVTFTDTPSGDAKQLTFNIFGYKFMAINAGPYFTKNPSISFTVLFNQSEAALLDKVWTALAHNGKIMMELDTYDFSEKYGWLEDQFGVSWQLLITDQPFDDRIRPSFMFINNNVGRAEEAINYYTSVFKNSGGISKFYYPEGMDPDKPDTLAHAEFKLEDQYFVALDSAHKHEFNLNEGISLMLFLEDQQEIDYYWDKLSTVPEAEQCGWVKDQFGVSWQIVPKIMDQMAEEGTPEQISNVTKAFLKMKKFDVETLIKAYEGK
>NZ_LS483305.1|WP_048540737.1|414384_415062_+|thiaminase-II
MKFTDRVFNRVEPIWQSYMEHPFIIGLGDGTLDQDKFKHWLKQDYIYLIEYARLFSIGAAKSTDLKMMATYADLANGTLNTEMSLHRGYAKQFGITEAELEETEPAQTTVGYTSYMLNMAQQGGIENVIAAILTCTWSYNYIGLKLVEIEGASDHPLYGEWINMYASDEFSQYKEDCIQLMDQVAEGKTEAELQRLEDIIVKTSYYEYMFWDMAEHLETWPVPIK
>NZ_LS483305.1|WP_048540800.1|413395_414127_+|epoxyqueuosine-reductase-QueH
MISADGIIAKMKNQKINYDKVMRKMISEWERSETRPSILIHSCCAPCSTYTLELLTQYADVAIYFANPNIHPKSEYERRARVQETFVEQFNERTNSNVKYIEAAYEPHEFMKMVKSKDLADENEGGLRCTACFEMRLELVAEAAADLGYDYFASALTLSPKKNAQLINELGMDVQDLYHVYYLPSDFKKNKGYERSIKMCNEYEIFRQCYCGCVFAAMKQGIDFKEVNKQAKAYLESCNKSCM
>NZ_LS483305.1|WP_048540735.1|411375_413292_+|PTS-sugar-transporter-subunit-IIBCA
MGKDNNKYKNISEQIVKVIGIENIESVTHCATRLRLSVHDRESIDDDAIEEIDEVKGVFYTGGQYQIILGTGIVNNVYDEMTNVHQFDEVSKETMKNQNQGNIQRAIRLLADVFIPIIPVLGATGLFLGLKGVVFNESVLGVFGATPEMIPNYIQTLITVLTDTAFAFLPAFIAWSAFRTFGGTPVIGFLIGLMLVSPALPNAYDVAGGDAKPIMVAGFIPIVGYQGSILTALFTGLVGAKLEKRLRKIMPNALDLIFTPFFVILLMMIFSLFIMGPIVHGIESVGITVVKSFIHLPLGLGGLLIGFIYPLAVMTGLHHMFIIVETSLLASTGFNPLITLAAMYGFSNAGVCLALSLRSQKSSFKTAGISATITQLLGVSEPALFGVVLRSGIKPLSIMLLCSALGGGVLALLNIQANSYGLAVILSPLMYIYDFSQLLTYIIVGVATFVLGFIITQLFGIPKSSMSDIDLNDEKVSDNLTDKHELKAINLKAVTNGEILSLADVDDPVFSQRMMGEGFGIIPNTDEVYAPVNGKVTLISDSKHAIGFETEDNLEILVHMGIDTVEIKEDVFNVLVKEGDIVQEGQLIAKMDINRILELGKQTTILTVITNSNEKVNELNLLKTGQSQSEDNIAKVIY
>NZ_LS483305.1|WP_048540753.1|421848_423231_+|amino-acid-permease
MEDNHLKRGLSSRQVQMIALGGTIGVGLFMGASSTIKWSGPSAILAYLVAGLFLYLVMRAMGELVYLYPTTGSFANYASDYLHPVAGYVTAWSNIFQWIVVGMSEVIAVGQYMQYWWPDLPTWIPGVIVVVTLAAANLASVKAFGEFEFWFAMIKVVTIILMIIAGFGLIFFGLGNGGNAIGLGNLTEHGGFFPKGIVGFFFALSMVVGSYQGVELIGITAGETKDPQKNIKKAVNGVIWRILIFYIGAIFVIVTVYPWDQLGNVGSPFVATFAKVGITIAAGLINFVVITAAMSGCNSGIFSSSRMVYTLAQKGQMPRIFTKVMKTGVPFFAVLAISIGIFVGVILNIVLPLVIDGSENIFVYVYSASILPGMVPWFMILFSHIQFRRHHSDEIKDHPFKMPFAPYSNYLTLGFFILVLIGMLFNSETRVSVIIGIVFLSVMAIVYFLRGYHKEDKGEY
>NZ_LS483305.1|WP_048540755.1|423862_424780_-|hypothetical-protein
MTIPIIIDTDPGIDDIIAISAALHSKELDVRLITTIGGNVGIERTTQNALDIVNYFHSNTPVAKGVDKPLINKLETAEHVHGQNGIGNAQIKTTLHNELLEEHAVIAMRDTILNSEEPITLVPIGPLTNIGLLFSLFPETKKNIKRIVLMGGAAVGGNATPVAEFNIFVDPHAAKIVFDQDIPIVMCGLDVTRETMINKDDLNIIQTQGDIGKVIIDMLSSYNDVNAGEEHEHIIHDLCTIFYLLYPEMFTTQRANVSVITEGQAAGCTYTEFSDEGKVEVCMHAQNKQFREKFVDFIKAIHQNQ
>NZ_LS483305.1|WP_048540757.1|425046_425409_+|helix-turn-helix-transcriptional-regulator
MNIGAKIKEEREINGWSQEELANKLHVTRQSVSKWELGKVYPGIDILVQMSDIFDVSLDELIKGDKNLKHTIIETYRNEPNHNQNYYDRPMNGWEFLSRFWWLVFPFGGIIIGIINALVQ
>NZ_LS483305.1|WP_048540759.1|425427_425988_+|serine-hydrolase-family-protein
MDKQLYIAHGYTADSKKHWFKWLTEQFEDIDSKILDFPNSSNPVLEDWNKTLLDEVDISSGNNVIVAHSLGVVTVLDYLSRYEGEWNVKGLVLVAGFYEKIPNLNKIDAYMDQTQVDFEKIIKQVPNIVSVIASNDRLVPRHLSERLAERLQSEEVIIQHVGHFCDSDGYTEFPEVAEIANDMFNK
>NZ_LS483305.1|WP_048540761.1|426067_426805_-|transglycosylase
MKKAFLTSSLAVAIGATGVASTQVADAAEQDVNKEQLAQLAQSNAPELNEHAIQEGAYNINFTLEGYEYNFQSDGQNFTWEYHATNAADSESTQAPVAEQQQPVAEENVAEQTPAPAANNTANEQATQEAPQQVEAPKQETQQTQETTTQTTQTSTSSSSASEGSNVNVNDHLKLIAQRESGGDLKAVNPSSGAAGKYQFLQSTWDSVAPAEYKGVSPTEAPESVQDAAAVKLYNTAGASQWVTA
>NZ_LS483305.1|WP_048540763.1|427418_427931_+|hypothetical-protein
MNKLTKLTIAAGISFGTIFGIVDFPGQDSHEVEAATTPYYTYKGYTGHDGSFILDSAFINALVYKNVTMNNYRIVQPQSYEGNIYTHRTSYDQTFYFGGKYEEEYAASAKFPVKKHHISKAQILKAYGNDYTIEETRNGEEYRFLVGGNLIIFTIDNNYVTTVNIGENLK
>NZ_LS483305.1|WP_048540765.1|428164_429778_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MNIINMSKLSKSYTGDLIFEDIKYDLNEGDCVGLVGRNGEGKSTLLKLMAGIEVPTEGQISWQKNISIGYLNQLPQYEEDKEIYECLSEVFKEINHISQKMKFLEDEMANNTNDLERLLKQYGALQETFQEIGGYERDALIRRVSHGLKINQLLNQTWGKLSGGERTKIGLAQILLQQPKLLLLDEPTNHLDISSVDWLSDFIKQYNGAVMIVSHDRYFLDETVNQILEIDQGHLHIYHGNYSYFVKEKEARIIREFEAYQTQQKKIKKMEDSIKQLRLWASQAKPPNAAMYKRAKSMEKALNRIKRLDKPVLENKKMNVNLTEGQRVSNDVIEFKKVSKMYEDILFEDIDLLIRRKEHVSIIGNNGTGKSTLLKMMMQQIEPDDGEVHCASNLRIGYLSQHTFENIENQTVIETFRDVVHVTEGQARHILAQFMFYGEDVFNTVESLSGGEKMRLRWAQIVNQDFNVLILDEPTNHLDIDSKETIEEALLDYEGTVIAVSHDRYFLNKLFDITYLLQDKQLTKYEGNYDYVKEKLS
>NZ_LS483305.1|WP_048540767.1|430280_431492_+|MFS-transporter
MKKFLKINDFYLILSSLAITRISESLLGIAVLWSLYVYTDSVYLVGLLTLFQVLPIIIFSFYSGALADSYNNKSILIITNLSRFILLMLSGLIFYIIQSDLLNIILLYILVFILAILTSFYLPSFQATIKKTISNQKLINANSSSEFIKHICNIFGLLLGGLLVDSLGLINTLFLGGLLFLGGAILMKIAYIPIFSQQIIDKKIKGSISESFSYLRKSSNLLQQSIYYLIIINISVAPISLIFVLMSDQLKLGSIGLSVLMISFSIGSIIGTICASYILKIVEESKVNYLLIVMYSVLVILTVLISNTILVVLLIFLTGITSSLSVIFINTFIQRETSNEFIGRVSSFRSLALRIPPPIIVMIFSYLVDILNIAYAAIIINSITIILATFVFIKRQKKMVGNE
>NZ_LS483305.1|WP_048540768.1|431593_432799_-|hypothetical-protein
MTLKEFNIIENQLINEYAGYFDKKELITQFPSKLSNINEEEFYFYMTKYLNKFHDPHLKLVDFNGLYPNIRVQLYNDQLYVIDSRNSQIPTGTVIHNLGSYSIDYILENDHDLLKSSNPERMEWSDVLKKYKYIVSDSKQISILQKDKPDFFEQSYIIENKSTYIYIKFTDFIDHLKISNLIDKHKNLLLNAKQIIIDVRGNRGGSDLAYLKLLPYLTTESITITDETPYYHRFTKSYCDERIHTISELIKQMPDSDDLDEYKSILNLYKDNYDKGFVNINNNPESDTIKGIQEKCPDVKVLADFECGSSGDNFVKIAHEFKNIEIIGRPTKGMNDYSNIMFIDINGKYKLSVPHSKDGNVDLGKSMGKTGIPVDHYIPWTPEELEKDIILEIAINRFTSH
>NZ_LS483305.1|WP_025906924.1|432868_433471_-|GntR-family-transcriptional-regulator
MANKELSIYQKIRNDIINGDLTQNEKITESKLAQRYNVSRTPIREAIKQLELEYFIRDGYIYVPTVEEYRNIFEMRILIETHAIKKASIVFTQDDIEELKSYATIGDDKTEEEIIQINDQFHQKIMSATKNSFIIDTYSKLKSYIYLFSKTVINKKRPGLIEEHQKIAEMLEKRQTEAAIELMKEHLLNDLEFSLYYLKS

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Crispr_ID: NZ_LS483305_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483305_2

1030800-1030958

Orphan

Consensus_repeat	Method
TGCGGGAGTATTTCAACTTTTAGAATACATTCCTTCCCGGAATGAGATATAGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483305_2

>merge|NZ_LS483305|2|1030800-1030958|CRISPRCasFinder
TGCGGGAGTATTTCAACTTTTAGAATACATTCCTTCCCGGAATGAGATATAGGTGCAAGTCCTATCTTCCGCTCCATTATTATTAATACTGCTATTTATTAAAATGCGGGAGTATTTCAACTCTTAGAATACATTCCTTCCCGGAATGAGATATAGGTG

>NZ_LS483305|2|2|1030800-1030958|CRISPRCasFinder
TGCGGGAGTATTTCAACTTTTAGAATACATTCCTTCCCGGAATGAGATATAGGTG	CAAGTCCTATCTTCCGCTCCATTATTATTAATACTGCTATTTATTAAAA
TGCGGGAGTATTTCAACTCTTAGAATACATTCCTTCCCGGAATGAGATATAGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483305.1\|WP_048539823.1\|1031690_1032656_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380509
NZ_LS483305.1\|WP_048539830.1\|1040701_1041754_+\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_LS483305.1\|WP_037590537.1\|1014844_1016584_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LS483305.1\|WP_048540691.1\|1013116_1014148_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_LS483305.1\|WP_048539822.1\|1031414_1031630_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237343
NZ_LS483305.1\|WP_048540692.1\|1016650_1018237_+\|FMN-binding-glutamate-synthase-family-protein	unknown	unknown	gnl\|CDD\|223147
NZ_LS483305.1\|WP_025907200.1\|1022330_1022783_+\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NZ_LS483305.1\|WP_048539827.1\|1035218_1035707_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NZ_LS483305.1\|WP_048539829.1\|1037017_1038424_+\|glucuronate-isomerase	unknown	unknown	gnl\|CDD\|376859
NZ_LS483305.1\|WP_048539825.1\|1033113_1034064_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380496
NZ_LS483305.1\|WP_048539826.1\|1034224_1035226_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270389
NZ_LS483305.1\|WP_048540695.1\|1020834_1021293_+\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NZ_LS483305.1\|WP_048540696.1\|1021298_1022252_+\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|240632
NZ_LS483305.1\|WP_025907189.1\|1014228_1014777_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NZ_LS483305.1\|WP_103354274.1\|1038467_1040567_-\|alpha-glucosidase	unknown	unknown	gnl\|CDD\|269885
NZ_LS483305.1\|WP_048539828.1\|1035706_1037002_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NZ_LS483305.1\|WP_048539824.1\|1032782_1033085_+\|DUF4440-domain-containing-protein	unknown	unknown	gnl\|CDD\|227327
NZ_LS483305.1\|WP_048540697.1\|1022808_1023249_-\|YgzB-family-protein	unknown	unknown	gnl\|CDD\|371346
NZ_LS483305.1\|WP_048540693.1\|1018273_1019368_-\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NZ_LS483305.1\|WP_048540694.1\|1019463_1020750_-\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493

Protein	Function_ID	Function_description	E-value
NZ_LS483305.1\|WP_048539823.1\|1031690_1032656_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380509	cd06286, PBP1_CcpB-like, ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. This group includes the ligand-binding domain of a novel transcription factor implicated in catabolite repression in Bacillus and Clostridium species. Catabolite control protein B (CcpB) is 30% identical in sequence to CcpA which functions as the major transcriptional regulator of carbon catabolite repression/regulation (CCR), a process in which enzymes necessary for the metabolism of alternative sugars are inhibited in the presence of glucose. Like CcpA, the DNA-binding protein CcpB exerts its catabolite-repressing effect by a mechanism dependent on the presence of HPr(Ser-P), the small phosphocarrier proteins of the phosphoenolpyruvate-sugar phosphotransferase system, but with a less significant degree.	5.81882e-90
NZ_LS483305.1\|WP_048539830.1\|1040701_1041754_+\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38766e-84
NZ_LS483305.1\|WP_037590537.1\|1014844_1016584_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NZ_LS483305.1\|WP_048540691.1\|1013116_1014148_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.94201e-134
NZ_LS483305.1\|WP_048539822.1\|1031414_1031630_-\|hypothetical-protein	gnl\|CDD\|237343	PRK13304, PRK13304, aspartate dehydrogenase.	0.000288458
NZ_LS483305.1\|WP_048540692.1\|1016650_1018237_+\|FMN-binding-glutamate-synthase-family-protein	gnl\|CDD\|223147	COG0069, GltB, Glutamate synthase domain 2 [Amino acid transport and metabolism].	7.1258e-137
NZ_LS483305.1\|WP_025907200.1\|1022330_1022783_+\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	4.24397e-53
NZ_LS483305.1\|WP_048539827.1\|1035218_1035707_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	3.61635e-32
NZ_LS483305.1\|WP_048539829.1\|1037017_1038424_+\|glucuronate-isomerase	gnl\|CDD\|376859	pfam02614, UxaC, Glucuronate isomerase. This is a family of Glucuronate isomerases also known as D-glucuronate isomerase, uronic isomerase, uronate isomerase, or uronic acid isomerase, EC:5.3.1.12. This enzyme catalyzes the reactions: D-glucuronate <=> D-fructuronate and D-galacturonate <=> D-tagaturonate. It is not however clear where the experimental evidence for this functional assignment came from and thus this family has no literature reference.	0
NZ_LS483305.1\|WP_048539825.1\|1033113_1034064_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380496	cd06272, PBP1_hexuronate_repressor-like, ligand-binding domain of DNA transcription repressor for the hexuronate utilization operon from Bacillus species and close homologs, all members of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor for the hexuronate utilization operon from Bacillus species and its close homologs from other bacteria, all of which are members of the LacI-GalR family of bacterial transcription regulators. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	2.2621e-65
NZ_LS483305.1\|WP_048539826.1\|1034224_1035226_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270389	cd13671, PBP2_TRAP_SBP_like_3, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.4742e-129
NZ_LS483305.1\|WP_048540695.1\|1020834_1021293_+\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	2.39181e-68
NZ_LS483305.1\|WP_048540696.1\|1021298_1022252_+\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.45821e-140
NZ_LS483305.1\|WP_025907189.1\|1014228_1014777_+\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	9.11255e-124
NZ_LS483305.1\|WP_103354274.1\|1038467_1040567_-\|alpha-glucosidase	gnl\|CDD\|269885	cd06599, GH31_glycosidase_Aec37, E.coli Aec37-like. Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic Escherichia coli strain BEN2908. The function of Aec37 and its orthologs is unknown; however, deletion of a region of the genome that includes aec-37 affects the assimilation of seven carbohydrates, decreases growth rate of the strain in minimal medium containing galacturonate or trehalose, and attenuates the virulence of E. coli BEN2908 in chickens. All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein.	0
NZ_LS483305.1\|WP_048539828.1\|1035706_1037002_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	6.17603e-125
NZ_LS483305.1\|WP_048539824.1\|1032782_1033085_+\|DUF4440-domain-containing-protein	gnl\|CDD\|227327	COG4994, COG4994, Uncharacterized protein conserved in bacteria [Function unknown].	2.51406e-13
NZ_LS483305.1\|WP_048540697.1\|1022808_1023249_-\|YgzB-family-protein	gnl\|CDD\|371346	pfam11023, DUF2614, Zinc-ribbon containing domain. This is a family of proteins conserved in the Bacillaceae family. Some members are annotated as being protein YgzB. The function is not known.	4.6157e-63
NZ_LS483305.1\|WP_048540693.1\|1018273_1019368_-\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.20795e-62
NZ_LS483305.1\|WP_048540694.1\|1019463_1020750_-\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0

>NZ_LS483305.1|WP_048540697.1|1022808_1023249_-|YgzB-family-protein
MEGIDLKLFRKKPTSKINRIRSFALGLIFLGMIVMYIGVFFFYYFKSQIVFSIFLVLGMLALGLSFIVYFWIGMLSSRTIQVQCPNCDHYTKMLGRADICANCNQPLTLDKNLEGKAFNQDYNNKRKSKKLEEQQTEEHAEEKKKS
>NZ_LS483305.1|WP_025907200.1|1022330_1022783_+|peroxide-responsive-transcriptional-repressor-PerR
MQQNIENVEHMLDDAIGTLRSTGVRITPQRQSILQYLIETDSHPTADEIYQSLSPQFPNMSVATVYNNLKVFKETGLVKELTYGDASSRFDFETHNHYHIICDQCGKISDFHYPRLDEVEQLAQHVTSFSVTHHRMEIYGVCPECQNKNK
>NZ_LS483305.1|WP_048540696.1|1021298_1022252_+|2-hydroxyacid-dehydrogenase
MKVVTLMRLKEQEERLKETFPNVDFIFYKHPNEARDEDLEDVDILVSYHGEVNPSFLDKCKNIKLIAWFATGVNQLPLDYIQDRGIKLTNARGVHAIQIAEFIFAYILNDIKLFRTSYESQKKREFNHKLKPDSINEKTILFLGTGKIPQRTAEVAKAFNMKVIGINTTGHVVPGFDEVYSIEERRHVYHKADFIVNVLPETEETIHLLQKEDFKQMNEDTHFINVGRGTVVSESVLYEALSSKDIRYASIDVFEEEPLPENSLLYDLDNVFITAHITGNDLNNLKRSTDILIENLKHIKNDASDKLINIVNAEAGY
>NZ_LS483305.1|WP_048540695.1|1020834_1021293_+|thioredoxin-dependent-thiol-peroxidase
MIQIGEKFPDFNLKNQNGELISNEDLKGSKVVVYFYPRDNTPTCTTEACDFRDNLEDFNELNTKVYGISGDSEKKHANFFNKHNLNFDLLVDEDYKLSEEVGVYQLKKSFGKESMGIVRTTFVLDEEGTVIHKIDKVKVKTQIEDLKNFIKE
>NZ_LS483305.1|WP_048540694.1|1019463_1020750_-|glutamate-1-semialdehyde-2,1-aminomutase
MEFTKSEYLQTLSNEYILGGVNSPSRSYKAVGGGAPVVMQKGKGAYFYDVDGNKYIDYLQAYGPIIAGHAHPHITEAIKAAAEDGVLFGTPTEYEITFAKKLRNAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRDKIIKFAGCYHGHSDLVLVAAGSGPSQLGTPDSAGVPKSVAQEVITVPFNDIDSFKEAMEHWGDQVAGVLVEPIVGNFGMVEPKEGFLEAVNEVTHQYGGLVIYDEVITAFRFHYGAAQDLLGVYPDLTAFGKVIGGGLPIGAYGGRQEIMEHVAPLGPAYQAGTMAGNPLSMRAGIALLEILEQPGVYDKLDQLGQQLEEGLLELIKKHNVKATVNRIKGALTLYFTDEKVENYVQAENTDGEQFAKFFKLMLNQGINLAPSKYEAWFLTTEHTEEDINQTLNAVDYAFSQL
>NZ_LS483305.1|WP_048540693.1|1018273_1019368_-|aromatic-acid-exporter-family-protein
MKFGARIFKTGIAIVLAIFIANLLPGPAMITSIAGVAAMVAMQPSVYRSFKTIVEQFQGNVIGAITAVAIFSIFGNNVVFIGLTAIIIISILYKFNLQHVSNLAVVTALIILGHHEGDFYISAFYRFVLVMIGVLSAFLVNFTFLPPKFETKMYYNSLNISTDIFKWFRLVLNGTTEFHYVKQDLETIRTRIVKLEQFYLYYKEERAYTKKQAFSQMRKKILFKEIIASTRRAYEVLRKMNRYENDIHNLNDDLKVQMKFELDELMAQHEQILVRISQKAKHEIDQVPDYLVEPYKEDLMEIFIKDIMDNPDQEDYYIENVMQVISAMLDYKATILHLDKLSSSYFKFHPEDSDIQIEDEDFDL
>NZ_LS483305.1|WP_048540692.1|1016650_1018237_+|FMN-binding-glutamate-synthase-family-protein
MTFLSILQLIVNILFFVIIIGGIIACISLYVIDKRQKHHSVLRNYPVLGRVRYFLESIGPELRQYLILNDNAGKPFSRKQYLNIVMPGKYKNRIESFGSLRKFEEPGFYLQNTMFPVDHDELEINQDEQMSTFIYEISNEGLFDRKEEQKQKDVDPYKLTSDNQIIIGDDLKHPFIVNRLIGQSGMSYGALGKNAITALSKGLGRSGSWMNTGEGGLSDHHLSGGCDIIFQIGPGLFGVRDKEGNFDETEFIEKANMNQVKAFELKLAQGAKTRGGHIEGAKVTEEIAEIRNVTPFETVNSPNRFEFLHNNKELLQFVQRLRELSDKPVGIKLVVGNINDLKKLIHEMVSSNIIPDFITVDGGEGGTGATYQELVDTVGLPLFSALPILDVELKKFKIRDKVKVFASGKLITPDQIAIALALGADLVNVARSLMINVGCIMAQQCHTNNCPVGVATTDPKKESALVVSEKEYRVSNYIVSLHEGLFNLAAAVGVKSPNQINENHLLYRSANGNVMNVKQYKKSIYKEQ
>NZ_LS483305.1|WP_037590537.1|1014844_1016584_+|ABC-transporter-ATP-binding-protein
MIKRYLQFVKPYKWHIVGTIIIGILKFGIPLLLPLLIKYVIDDVINNGALSIGQKTEKLTYAMLIMGFIFVVLRPPIEYFRQYLAQWTSNKILYDIRKKLYTHLQALSSRFYANNKAGEVISRVINDVEQTKDFILTGLMNVWLDLVTIVIALSIMFVLDIKLTFTAIAIFPVFIFSIYYFFGKLRSLTRRRSQSLAELQGFLHERVSGMSVIKSFAIEKNEEKRFDKRNQNFLTKATDHTKWNAKSFAVINTVTDIGPLLVVGIGGFLVIQGNLTVGTLAAFVAYLEQLYGPLRRLVSSSTTLTQSIASMDRVFHLFDEKYDVKNEDDAQDIVIKEGHITFDDVSFKYNDYEDEVLKHINLDINKGETVAFVGMSGGGKSTLISLLPRFYDVTKGSISIDNHNVKDFTTESLRNQVGMVEQDNILFSDSIKENILLGKPDASDEEVIEASKKANAHDFIMSLPNGYDTEVGERGVKLSGGQKQRVSIARIFLNNPPVLVLDEATSALDLESEKIIQDALEILSTERTTLIVAHRLSTITHADKIVVIQNGQIEEVGSHKELMAAQGSYYNLYNIQSFG
>NZ_LS483305.1|WP_025907189.1|1014228_1014777_+|DUF402-domain-containing-protein
MVKESIPKEGQVIKIQSYKHDGNIHRVWSETTILKGTSHVIIGGNNRTLVTESDGRTWVTREPAIVYFHSEYWFNVICMFREDGVYYYCNLSSPFVCDEEAIKYIDYDLDIKVYPSGKYHLLDEDEYKQHMKQMNYPKDIDVILRRNVDILQQWIERKKGPFAPDFIKVWQERFHSIDRRNS
>NZ_LS483305.1|WP_048540691.1|1013116_1014148_+|A/G-specific-adenine-glycosylase
MIETKQFKDDLLNWFHKNKRQMPWRETSNPYYIWLSEVMLQQTQVNTVRPYYKAFIERFPTIESLSEANEEDVLKYWEGLGYYSRVRNFQEAVKEVHHSYHGVVPDNPDDFKKLKGVGPYTNAAVMSIVHNHPIPAVDGNVLRVWSRLTGNDSDIAAPKTKKLYEDELQPFVEEHSGDFNQAMMELGATICTPKKTLCIMCPVQKHCYAFANGVVEELPVKKKKIKKKTIDFNVLYITNRSGEILVRQRDTKLLNGMWEFPMFEADESIHSIEETLDAVIDIDQTPEFTTKHVFTHMTWNMNVYRAHTQKSEFDYPYKWIKKEEKDQLSFSTSMSKIFNQLNG
>NZ_LS483305.1|WP_048539822.1|1031414_1031630_-|hypothetical-protein
MNKQKVGIDGCNITSEIYVEILQHTSNIDIVACTDESLSKAISMKNKYDIPQVMTRSKMYKDKKIDYIIKL
>NZ_LS483305.1|WP_048539823.1|1031690_1032656_-|LacI-family-DNA-binding-transcriptional-regulator
MTNLKEVAKRAGVSPSTVSRVINNHPYVNEEKRQKVLDTIEELNYIPNINAIHLKKGKTNLIGVVLPFSNHPYFSQLIQGISEEAIKSNKKIVLFQTAYDTDQEIDALEMLKLKQIDALIICSRNISLNIVEQYIEYGPISIFENISNSKFRTTYIDHYNAFKQALNHLYNNGHRHIACAINRRNSTSSILRIQAYKDFCSENSITYNDQDIYENFVLLEDGQRLAQEIENKENPTTAIVVSGDNTAAGLFISLDEEKKKNISIIGFENHKISKLLNLTTIEIPLFQIGKSLFNQLYEDKLNNYLFETKLIKRNSVFKLNH
>NZ_LS483305.1|WP_048539824.1|1032782_1033085_+|DUF4440-domain-containing-protein
MDASNREDKSFIINLLDDDFKEIGKSGRMIYKRDIEENTLHTFDYEISDFIVEKIQKGIVLTTYELINKTDHISTKRSTLWIRKQSEWKMRFHQGTIVKK
>NZ_LS483305.1|WP_048539825.1|1033113_1034064_-|LacI-family-DNA-binding-transcriptional-regulator
MAVTLKDIANACGVSYSTVSKALKNSPLVTAETTERIQQKAKEMNYIPNNSARSLVSNKSQTIGLIWPSVDRVAVSTLVSEINNFLKNTGYFMSVSIDDVETAAHKFLELRFDGIIVFDEGEASTLPSIISSNIPVVAYGTDRKLEYPIVNVNHKHAMILSLDDLMQNNITNICYIGDLNTDDIRQIIKKETFEHYCKEHHLNYNMIDSKGLSAEDTFFALKSYLTNHTLPEGIICGSYDITLGLIHTLKDSLDQHIVYSYDNVPQFDHMDTVIHSVGVPTKKIAETLVNILINAIEYKENQPDVYHLEPELVKRK
>NZ_LS483305.1|WP_048539826.1|1034224_1035226_+|TRAP-transporter-substrate-binding-protein
MKKILLLIVSVFIVLYGCQQSDAQDKDVKTLTLAHNQSTTHPVHKSLEEFKKEVERKSHGKLKIKIYANGQLGSEREAIEMTQTNAIQFTKVSASALESFSESYSLFSMPYLFKSQDSFRSIMKKPEVQNSFFNTTKDNGFVGITYYDAGLRNIYTKDREIKTNKDLHGLKTRVQPSKTSVELIKSLGGTPTPMAFGEVYTALQSGVIDAAENNETALTDNKHGEVAKNYYNTEHAIVPDILIMNKDAYNDLSKEEKGWIKSAARSSTEKHEVIWDKAIKEGIKTAKEDMNVKFHDVDKSSFKKAVKPLQEEFKNNKGTEKQYKLIKEAEQNE
>NZ_LS483305.1|WP_048539827.1|1035218_1035707_+|TRAP-transporter-small-permease
MNKLTHYIDRTLLSVSGVLVTVMVILSVWQVITRYILNTPSTTSEEIIRFLLIWFALLSAAYVFGKKKHIAILFIREKFPVKAQLFIERLTNIIILLVALILMIYGGIKIVALTWTQIAPSTGVSMALMYGALPISGLFIAFYSIRGIITNELPENDEGGEV
>NZ_LS483305.1|WP_048539828.1|1035706_1037002_+|TRAP-transporter-large-permease
MTTIAGIVLFVSLAVFLAFGIPIAISIILSSLLTLILIFPFDVTILTAAQRMITGIDNFTMLAIPLFVLAGILMNNGGIAFRLINFAKVLVGRLPGSLAHTNIVGNMLFGSISGSSVAAAAAMGRIMTPMETTQGYKKSYSAAANIASAPSGLLIPPSSLLIVYSLVSGGTSIAALFIAGYIPGILWGLGCMVVAYFLAKKHGYPVSEKVSWKDKLFLTLDAIPSLLLIIIVIGGIVAGIFTATEGAAVAVLYAFILSLIYRNLKIKDIPAIIIETVEITGMILFLITASALFSLVMSFTGLPEAISGGILSLTENPILLLLLMNLILLIVGTFMDITPAVLIFTPIFLPIADSIGLDPIHFGIVIAFNLCIGNITPPVGSALFVGSSVANVRIESVIKTLIPYFIILIILLLLITFVPQLSLFLPKLLGL
>NZ_LS483305.1|WP_048539829.1|1037017_1038424_+|glucuronate-isomerase
MSMIQENFIVQSKKGQALYKVAKDIPIFDFHCHLDPKEIYENKPFTTITEVWLKHDHYKWRLMRAYGIDESYITGDKSDKEKFDAFISLLPKSIMNPMYHWCHLELARYFNINENLNKIDKEQLYNQLNESLQQPEFLPRKLIERSNVQIICTTDDPCDDLKYHQLLREDKSFDVKVLPTFRPDRYIALTKDNVEASINQLENATGTRINHLEEYINALNERIEYFHQNGARSSDQSFAKVLKVDVTKEQADQYFEQIKQGEDLDEEDLSRLSGYILTEVSKTYKKYNWVVQFHLGPVRNNNTLLFEEVGPDAGFDSVGDMLSSSDLNRFLDHLNQNDALSDTIIYPNNANDHLMVQATAGNFTSDKVKVQLGAAWWFNDTKEGMEQHLVEYANVGLLSTFVGMLTDSRSLLSYTRHEYFRRILCEMIGKRVERGEIIDDDEILSEIIKDICFNNAVTLYNIEGVDAI
>NZ_LS483305.1|WP_103354274.1|1038467_1040567_-|alpha-glucosidase
MYMFNMISQDKNTIVISDKQNEHFFTIRILEDYLINIKSSTQKDISLPTWTITPGDTDLPFEGLSRYDQSNFSCPQYEISEEQHNIIIETKLLKLIIDKEDFYCSWYDLSSSDKEIKIMQDRQTGSYHHQISKNHPTCHYLNRDKNEMYFGLGEKSGKVNKHGRRYRMKNIDAMGYNAETTDPLYKHIPYYLTYNTDENIAFGIFYDDYQDSIVDLGQELDNYHGHYRYYETKSDFLDYYVIAGPSIQQVTTRFSHLTGRPTLMPEWSLSYSGSTMQYTDLPNSDERLLSFLNQCNTHNITIRSFHLSSGYTSIHDKRYVFNWNYDKFKDPKSFGKAYTDQNVELVANIKPTLLTDHPLLDEVLAIDGFIKDMNGKPLLVQFWDEKGYYLDFTNKDTIKWWQSKIEQQLLSNHVNCTWNDNNEFEIWDDKAIVNGFGNEANFQDYKAIMPILMMKASREIQQKYHKEEYPYIISRSGAAGMSKYVQTWTGDNYTSWHTLKYNNAMAIGLSLSGVYNFGHDIGGFSGDKPEAELFLRWVQCGAYYPRFSIHSWNDDGTVNEPWMHQKVLSEVKQAMHFHEKLKPYLQSLVIQAHESYEPIIRPTFYQYENDITTFVENDEFMLGEHMLIAPIVEKSQQERTIYLPNNNKGWIDFHSGKQFEGGQTITVKTTLQHIPTFVVKGAEIPVYKDDLKTIENLKF
>NZ_LS483305.1|WP_048539830.1|1040701_1041754_+|PTS-transporter-subunit-IIC
MDKHFTVKEFFFNILNGIGVGIVIALIPNAILGVLFSYLSQFHPLLEMFNQALLLMQFAMSFIIGIVVAHQFKFQATDAVMIGAAGLIGSGAVKIQNGQFIFVSIGDVVNLIVVLIISCYLMIKLKGKFGSLDMLIMPIIISVVSGFIGMLTLPYVSNVTKGIGKLIEQFSTLNPLMMCILIAITYALLMVTPISVVAIATAVGLNGLSSGAGNMGIVAACVTFLMGSWKVNEKGINIVLIIGAAKMMIPVYFKNPIIAVPLIVNGLMSGLLTYFIGIKGTPMSTGFGYTGFVGPANALKFMEGSVFLNILILGVAYFVIPFVFAYIVHKVCLKILPKYNQEMFLFKENN

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Crispr_ID: NZ_LS483305_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483305_3

2105673-2106054

Orphan

Consensus_repeat	Method
CAAAACTCGGNCGAAGTGTTAC	CRT

9 spacers

The CRISPR arrays of NZ_LS483305_3

>merge|NZ_LS483305|3|2105673-2106054|CRT
CAAAACTTGGCTGAACTGTTACTAAGGGCGGCTATATTTACAAAACTCGGTCGAAGTGTTACTATGGGCGGCTATAATTACAGAACTCGGTCGAAGTGTTACTAAGAGCGGCTATATTTACAAAACTCGGTCGAAGTGTTACTACAGACCGCTATATTTACAAAACTCGGCCGAAGTGTTACTAAGAGCGGCTATATTTACAAAACTCGGTCGAAGTGTTACTAAGGATACCCATAGTTACAAAACTCAGCCGAAGTGTTACTACAGACCGCTATATTTACAAAACTCGGCCGAAGTGTTACTAAGAGCGGCTATATTTACAAAAATCGGTCGAAGTGTTACTAAGGATATCCATAGTTACAAAACTCAGCCGAAGTGTTAC

>NZ_LS483305|3|1|2105673-2106054|CRT
CAAAACTTGGCTGAACTGTTAC	TAAGGGCGGCTATATTTA
CAAAACTCGGTCGAAGTGTTAC	TATGGGCGGCTATAATTA
CAGAACTCGGTCGAAGTGTTAC	TAAGAGCGGCTATATTTA
CAAAACTCGGTCGAAGTGTTAC	TACAGACCGCTATATTTA
CAAAACTCGGCCGAAGTGTTAC	TAAGAGCGGCTATATTTA
CAAAACTCGGTCGAAGTGTTAC	TAAGGATACCCATAGTTA
CAAAACTCAGCCGAAGTGTTAC	TACAGACCGCTATATTTA
CAAAACTCGGCCGAAGTGTTAC	TAAGAGCGGCTATATTTA
CAAAAATCGGTCGAAGTGTTAC	TAAGGATATCCATAGTTA
CAAAACTCAGCCGAAGTGTTAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483305.1\|WP_048541988.1\|2105293_2105497_+\|YjzD-family-protein	unknown	unknown	gnl\|CDD\|371396
NZ_LS483305.1\|WP_048541974.1\|2112162_2113494_+\|CoA-disulfide-reductase	unknown	unknown	gnl\|CDD\|184103
NZ_LS483305.1\|WP_048541990.1\|2102906_2104151_-\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NZ_LS483305.1\|WP_048541992.1\|2099005_2100079_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_LS483305.1\|WP_048541993.1\|2098040_2099006_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224048
NZ_LS483305.1\|WP_048541978.1\|2110485_2111298_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
NZ_LS483305.1\|WP_048541976.1\|2111310_2112156_+\|DegV-family-protein	unknown	unknown	gnl\|CDD\|273257
NZ_LS483305.1\|WP_037588863.1\|2115656_2116001_-\|YisL-family-protein	unknown	unknown	gnl\|CDD\|237465
NZ_LS483305.1\|WP_048540113.1\|2114081_2115503_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|200451
NZ_LS483305.1\|WP_037588862.1\|2116207_2117113_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NZ_LS483305.1\|WP_025905685.1\|2102471_2102843_+\|DUF3899-domain-containing-protein	unknown	unknown	unknown
NZ_LS483305.1\|WP_048541991.1\|2100093_2101164_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_LS483305.1\|WP_048541996.1\|2096182_2097853_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_LS483305.1\|WP_048541997.1\|2094437_2096093_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NZ_LS483305.1\|WP_037588867.1\|2110056_2110365_-\|metal-sulfur-cluster-assembly-factor	unknown	unknown	gnl\|CDD\|225062
NZ_LS483305.1\|WP_048540115.1\|2117189_2118317_-\|DUF418-domain-containing-protein	unknown	unknown	gnl\|CDD\|225193
NZ_LS483305.1\|WP_048541989.1\|2104165_2105107_-\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NZ_LS483305.1\|WP_048541987.1\|2106280_2108878_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NZ_LS483305.1\|WP_048541982.1\|2109048_2109741_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483305.1\|WP_025905684.1\|2101163_2102090_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674

Protein	Function_ID	Function_description	E-value
NZ_LS483305.1\|WP_048541974.1\|2112162_2113494_+\|CoA-disulfide-reductase	gnl\|CDD\|184103	PRK13512, PRK13512, coenzyme A disulfide reductase; Provisional.	0
NZ_LS483305.1\|WP_048541990.1\|2102906_2104151_-\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NZ_LS483305.1\|WP_048541988.1\|2105293_2105497_+\|YjzD-family-protein	gnl\|CDD\|371396	pfam11151, DUF2929, Protein of unknown function (DUF2929). This family of proteins with unknown function appears to be restricted to Firmicutes.	8.29487e-10
NZ_LS483305.1\|WP_048541993.1\|2098040_2099006_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	1.52919e-126
NZ_LS483305.1\|WP_048541978.1\|2110485_2111298_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.1212e-83
NZ_LS483305.1\|WP_048541976.1\|2111310_2112156_+\|DegV-family-protein	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	1.0236e-91
NZ_LS483305.1\|WP_048541991.1\|2100093_2101164_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85357e-100
NZ_LS483305.1\|WP_037588863.1\|2115656_2116001_-\|YisL-family-protein	gnl\|CDD\|237465	PRK13673, PRK13673, hypothetical protein; Provisional.	3.93775e-24
NZ_LS483305.1\|WP_048540113.1\|2114081_2115503_-\|hypothetical-protein	gnl\|CDD\|200451	cd00551, AmyAc_family, Alpha amylase catalytic domain family. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; and C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost this catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	3.97969e-23
NZ_LS483305.1\|WP_037588862.1\|2116207_2117113_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.68815e-85
NZ_LS483305.1\|WP_048541992.1\|2099005_2100079_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	0
NZ_LS483305.1\|WP_048541996.1\|2096182_2097853_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_LS483305.1\|WP_048541997.1\|2094437_2096093_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_LS483305.1\|WP_037588867.1\|2110056_2110365_-\|metal-sulfur-cluster-assembly-factor	gnl\|CDD\|225062	COG2151, PaaD, Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only].	1.07141e-41
NZ_LS483305.1\|WP_048540115.1\|2117189_2118317_-\|DUF418-domain-containing-protein	gnl\|CDD\|225193	COG2311, COG2311, Predicted membrane protein [Function unknown].	7.08885e-68
NZ_LS483305.1\|WP_048541989.1\|2104165_2105107_-\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	2.31343e-176
NZ_LS483305.1\|WP_048541987.1\|2106280_2108878_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NZ_LS483305.1\|WP_048541982.1\|2109048_2109741_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	6.69985e-38
NZ_LS483305.1\|WP_025905684.1\|2101163_2102090_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	6.6698e-111

>NZ_LS483305.1|WP_048541988.1|2105293_2105497_+|YjzD-family-protein
MQYILTFIWAFLLSQMINFVLHSLGGSDEALNFVSPTIYAIIFTVVIILLDALVGKSTSDKQSTQHS
>NZ_LS483305.1|WP_048541989.1|2104165_2105107_-|ketoacyl-ACP-synthase-III
MDIGIKGFGAYAPKQVVKNGYFESYLDTSDEWITKMTGIKERRFADDTEDTSDLAYEAAVRAIEDSGIDKEEIEMIIVATSTGDKPFPTVATTLQKRLGLNKVPSMDQLAACTGFIYGIVTAQQFVQSGLYKNVLVVGADKLTKITDMNDRSTAILFGDGAGAAIIGEVSEGKGILSVELGSDGNGGPYLYQDMDANTIQMNGREVFKFAVRIMGEASTKAVEKAGLQSDDIDMFVPHQANIRIMESARERLGIAKEKMSVTVDRYGNTSAASIPLSIAYELEQGKIKDNDTIVLVGFGGGLTWGAITLRWGK
>NZ_LS483305.1|WP_048541990.1|2102906_2104151_-|beta-ketoacyl-ACP-synthase-II
MTEKKRVVMTGLGTLNPLGNDVPTTWENAINGKNGIDEVTRIDVSEFPAKLAGELKDFNIDDHIPKKDARKMDRFTQYAIVAAREALKDSKYEITVENSHRVGVWIGSGIGGMETFEYSHNMLLKRGPKRVSPFFVPMMIPDMATGQVSIDLGAKGPNGCTVTACATGTNSIGDAFKIIQRGDADVMLAGGTEAPITEMAMAGFSANKALSTNPDKNTACRPFQEGRDGFIMGEGAGVVVLESLESAEARGAHIYAEVVGYGSTGDAFHITAPSPNGEGGARAMQEAIKDAGIKPEDIQYLNAHGTSTPIGDLYEVLAIKSTFGDAAKNLKVSSTKSMMGHLLGATGAVESILTALSIENSIVAPTINANTPDPEIDLDYTPNEAAKLDIEYAMSNSLGFGGHNAVLVFKKYQK
>NZ_LS483305.1|WP_025905685.1|2102471_2102843_+|DUF3899-domain-containing-protein
MKFWGIFTIGYIGLFAVLCLIFLKDLDQAANIYFYIMTIAFAASWIVAMKQDGVGEVSRQAVRKFNFHMKSKASQDYLKDDEIMNPNMKELHLKERTIHNWVLPFVVLSTLFFIISIFLGFIV
>NZ_LS483305.1|WP_025905684.1|2101163_2102090_-|ABC-transporter-permease
MVRYTLKRIIYMFISLFLIMTITFFLMKLLPGSPYNDEKLSEEQKVIINEKYGLNDPVPVQYANYLKNVAKGDFGISFQYDNREVWSLIKPRLGPSVEMGTYAMILGTITGLLLGIVAAIRQNTIVDYGATFLSVIFISVPSFVLAVLLQYVFAVEWQIFPVAGWSGFMTAVLPSIALAAGVTATIARYIRSEMIEVLSSDYIELARAKGMSSARVIFGHAVRNGLIPIITIIVPMLAGILTGTLTIENIFGVPGLGDQFVRSIQTNDYPVIMALTLLFSFLFIISIFLVDVLYGLVDPRIRVEGGKK
>NZ_LS483305.1|WP_048541991.1|2100093_2101164_-|ABC-transporter-permease
MANNDDNKLNNSGYDNASVTHSTQGMPAESFVLHGRDKVVEEKFERKSRTFWQDAWKQLVGNRLAIIGLIFLILLTVISLVGPLMNDHKFSDQNVSHANLPPKIPVLDKVPFLPFDGTDRDGFDLYESQNVQENYWFGTDELGRDLWTRTWRGTQVSLFIGVVAAALDIFIGVIYGAVSGYFGGRIDDILQRIVEILSSIPNLIVVILFVLLFDPSIWTIILAMSVTGWLGMSRIVRGQFLKIKEQEFVMASRTLGVSNFKLIFKHILPNTLGPIIVTSMFTVPSAIFFEAFLSFIGLGIPAPQASLGSLVDTGRKMLLIYPHELFVPATVLSLLILFFYLFSDGLRDAFDPKMRK
>NZ_LS483305.1|WP_048541992.1|2099005_2100079_-|ABC-transporter-ATP-binding-protein
MAKRILEVNNLHVSFDIDAGEVQAVRGVDFYLDKGETLAIVGESGSGKSVTTKALTRLLPKKVGRIKDGSILFDGKDIAKLSEKEMQKIRGKEIGMIFQDPMTSLNPTMKIGKQVMEPLIKHQKLSKQDAKKRALDILNLVGLPKAKERFNNYPHQFSGGQRQRIVIATALACDPKILIADEPTTALDVTIQAQILELMKELQHKIDTSIIFITHDLGVVANVADRVAVMYGGQIVETGSVDEIFYNPKHPYTWGLLSSMPSLETSHDTELLAIPGTPPDLIKPPVGDAFARRSEYALDIDFKEEPPWFQISPTHFVKSWLLDERAPEVELPEAVKLKQKATPDQFDKPKRVERVTF
>NZ_LS483305.1|WP_048541993.1|2098040_2099006_-|ATP-binding-cassette-domain-containing-protein
MADKKEVLIDVQNLKQYFNVGKKNEVKAVDDISFQIFKGETLGLVGESGCGKSTTGRTLIKLYDATDGKVIFDNVDIQNIKKRKDLLRFNRRMQMIFQDPYASLNPRLKVMDIIAEGLDVHKLVSSKEERKKRVYELLETVGLNKEHANRYPHEFSGGQRQRLGIARALAVEPEFIIADEPISALDVSIQAQVVNLMQKLQDEKGITFLFIAHDLSMVKYISDRIGVMYFGKLVELGPSDQIYKHPQHEYTKSLLSAIPLPDPDSERTRTRSSYNPDIHKYEDDDKLELREVGPDHFVYCSEKEFAEKKANYNKDFDLTEA
>NZ_LS483305.1|WP_048541996.1|2096182_2097853_-|peptide-ABC-transporter-substrate-binding-protein
MRKKISVLLSILVAAVLTLAACSGGGSKSDEGGKGGVKSEKSENVLNLASTSDIPTMDSSLATDQVSFFTFNQTLEGLYVLDKDDNPAPGVAEADPEKSADGKTWTIKLRDNAKWSNGDPVTAHDFVYAWQRTVNPDTAAEYAYMFENIENAKDITAGKKKPEELGVKAIDDQTLEIKLIKDVPWMQSLFAFGSFMPQNEKFVEKQGKKFGTTADATLSNGPFIMKEWKTEDNWKLVPNKEYWDKDKVKLKEVNYKVVKEVQTAVNMYQTGKLDTVSLDSSNVNKYKDREDFSTQLNSSNFFFRINKTKNKDLENQDLRKAFAKSIDKEQYVKSLLNNGSVPSDKLMVKDFVKDEDGKDYIDGVKSPLGYDKEEAKKLLEKAKKATGKDKFNIELLTYDADESKKAAEFVKEQVEKNLPGVTLKIKQQPFKQKLALESKGDYDISFAGWGPDYPDSTTFLDLFKKNSPHNQTGYANAEYDKALEEANSDEMLKDENSEKRTKLLQDAETKFLDSASIGPLYQQGVARLRQPYVKNWQPHKFGGDYSLKEVEIAGAK
>NZ_LS483305.1|WP_048541997.1|2094437_2096093_-|peptide-ABC-transporter-substrate-binding-protein
MKKYKVIFMIVVSLMLILSACSNDKDEKGSNIKQSKSKNELNLSSGDDIPTMDPSLAADQVSFTTFAQTLEGLYVLDKNDKPIPGVAKDKPKKSSDGKTWTIQLRDNAKWSNGDPVTAHDFVYAWQRSVDPDTAAEFAYMFENIENAKEITQGDKKPEELGVKAIDDHTLQIKLIKDVPWMESLLAFGSYMPQNEKFVEKQGDKFGTTAKTTLSNGPYKLTEWKPEDKWKLEKNDEYWDKDKVKVKDVNVKVVKNTQTAINMYQTGKLDMVGLDAQNIKKYKDREDFSTEATSGSYFFRINKEKNENLKNEDLRKAIAKSIDKKSYVNSLLNNGSKPLDTLMIKDFVKDSDDKDYTEGVKSSLSYNKKDAKDHLEKAKKDLGKDKFTIELLTYDEDESKKAGEFVKEQVEKNLPGVTLKIKQQPFKQKLALESKKDFDISFAGWFPDYPDPTTFLDLFTSDSPHNQTGYANKAYDKALEEANSDEMLKPENSDKRIKALQDAESEFLDSASISPLFQTGSARLRQPYIKNWQNHKYGGDYTLKGVEIEGAK
>NZ_LS483305.1|WP_048541987.1|2106280_2108878_-|ATP-dependent-chaperone-ClpB
MDINQMTYSVQSAIEQAQQLSQSYQLQNIEIEAVLLAALNEDESIYKRTLERANIDTEILKDKYEQKLKQYSVVKGDNVQYGQYISPKLNELFNKADKIKEEMQDDYMSMEHILKAAIEVDQTTIDMVGNKKEVVNEIINKIRGGNRVTSQNPEVQYEALSKYGRDLVEEVRKGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKRDVPESLLDKTIFELDLSALVAGAKFRGEFEERLKAVLKEVKESEGRILLFIDEIHMLVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLNEYRQYIEKDSALERRFQKVSVKEPDLEDTISILRGLKERYEVHHGVRIQDRALVAATELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDAVNRRVMQLEIEENALKSESDQSSQIRLEELQKELADEKEKQQQLQSKVEQEKEQIKSLQDKRAELDESKQALENAENQYDLAKAAELKHGKIPQIEAELKELEEAFAEETGSDHDRLIREVVTDEEIGYIVSQWTGIPVSRLVETEREKLLKLSDILHERVVGQDEAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDSEKHMIRIDMSEYMEKHSVARLIGAPPGYVGYEEGGQLTEAVRRQPYSVILLDEIEKAHNDVFNVLLQLLDEGRLTDAKGRSVDFKNTIIIMTSNIGSQYLLDGVTENGEIEESAKKQVNDSLHAYFKPEILNRMDDIVLFKPLSIKDMSHIVDHIITNLNIRLVDQHIKVSVDQDVKEWIAEEAYEPQFGARPLKRFVQRQIETPLARLMIGQELKEGTIVNVHLVDGEVKFEVNA
>NZ_LS483305.1|WP_048541982.1|2109048_2109741_+|Crp/Fnr-family-transcriptional-regulator
MQTTYTEATSIIEYIIQHGQRHHFDAHHYIYHTGDLCNHIYVIVEGKVITHRVMEDGKEFNTKLLGRHSIFGSTTLFCGRKTHSLSARVKEAAVVFSIPKVQFEEAILNDEVLKYEWLLWVQNENEKNEYQIRDVYTLGKTGAFYSILIKLANTYGIQGGNSILINVDLTNHELANFCNVTRESVNRMLSNLKKEKIVSINHKKITIHDLDYLKRAINCENCPLSICRIE
>NZ_LS483305.1|WP_037588867.1|2110056_2110365_-|metal-sulfur-cluster-assembly-factor
MEEAMKDSIIGALENVIDPELGIDIVNLGLVYNVDLDDEGLCTVEMTLTSMGCPMGPQIIDQVKTALAELPEIKETEVNIVWNPPWGKDKMSRYAKIALGVS
>NZ_LS483305.1|WP_048541978.1|2110485_2111298_+|Cof-type-HAD-IIB-family-hydrolase
MEKHLICLDLDGTLLNDEKRISPFTKRVLQYLKKSGHEIMISTGRPYRASVDYYNAMNMNTPIINFNGAYIHHPTDNRFPTKHEQFDTRIAYKIYKDISQLDIKNIIAEVKDQVYINNYDQSLFEGFSMGNSEIKYGELDQLLPESPTSLLIQAEESEIPRIKRHLNKHYAEFIEHRRWGAPFPVIEIVKKGINKGKAVKYVAEYLDIDFDNIIAFGDEDNDFEMIQFANYGIAMGNAIPELKEIATEVTDTNNNDGIGKYLNKHFDLNM
>NZ_LS483305.1|WP_048541976.1|2111310_2112156_+|DegV-family-protein
MKMIVDSGSDITLSQIEEKGFYFLPFGIVIDDQNKVDQYEISNEEVLAAIKNNKHPKTNQATMEQMTKVFTEVAEKKEKAIYLAFSSALSGTYQTACLVKEQVKETYPDLDLTIYDTLSASMGCGKLILDVQDKIEQSYTFEELDAYIKERIDKIRHLFTVKDLNYLASGGRLSKGQAFLGNLLNIKPLLHVEEGKLVPIEKYRGSKKLWHAIIDKMQNENSDYSDDIIYMTHADDIEEAEKIKALIQSSLSPQDVVISNIGPVICSHTGSGTVAIFYYKE
>NZ_LS483305.1|WP_048541974.1|2112162_2113494_+|CoA-disulfide-reductase
MAKIIVIGAVAGGATVASQIRRLDPDSDITVYEKDRDMSFANCGLPYYLGEVVEDRNMMLSATPEQFKDKKHITVKTYHEAIELNDTKKTIAIKNHETGEIFEDAYDKLILSPGCRARHLGFQSDRVFTLRNLVDTDKIEDFIQKENVQSALIVGAGYVSLEILENLYNRNIQTTLIHRSDHINKSMDKDLNKVIFDELEKRHIPYRLNEEIADISGREVTFKSGKTESYDLVITGVGIEPNSDWLKSSSLKLNEKGYISVNEYFETNLEDVYALGDVIETFYRHTKKPTSVTLAWGAHRAAALIAENITSKSSSSKATFKGLLGTNIVKMFDYALGSVGVSESELSNYDYEVVEQTQKQHAGYYPSAEPLTLRVYFDKATRKILRACAVGKDGADKRIDIISTAIIGNLTVDELRDIEIAYAPPFSSPKDIVNMIGYKAQSK
>NZ_LS483305.1|WP_048540113.1|2114081_2115503_-|hypothetical-protein
MNKWTKIIISIILIAPLFSSYVFAKEKEYEDVKYPRIYSLVVDRFMNGNNDNNKMIKNNNQSNDLPLGGDFQGIESKLDYIHDMGFNTIHISPVFSHDQKDFLGYKVKNYDDIDKVLGGEKAFKSLVDKVHNKDMKIIVDMPVTYTDEFKQFTDGDLNQIQKSYFKNDQFIDLKNSENQSIYKAKVKNFVDKYHIDGVSMNIVQDGIDAEAFLPEGLDTYGIINKDGINVKNFKHLSTNATRTAIQNAFKTENTEIPTYNQKGEVLIADTWFTERFTKHAADENKFPGTRIKQLMTYMWGYKGPVMMNYGTEIAVNGSKIETINQLQNFRTDKEVIKYLEKIADTFKQYQELYEGKVKVLPHDKGTNLFYYDTNTIDYILNINDSSKSKKVTLDDKLIEKNKMLSGLILGDNIKGKDNRYDLITDREESELYAIINERGLNNSYLVAAVLVILLFGLFIFLVSRRSKRHKNNQ
>NZ_LS483305.1|WP_037588863.1|2115656_2116001_-|YisL-family-protein
MIHFHIFSWLVTIILFFVVYMKVTNKPVHMVLRLFMVFTLISGFVIFMQAMGINGMLYGIKFILGLAVLGLIEVTIAKKKKNKNSQGLFIATIVVMVLTILLGSYLPMGVLHFG
>NZ_LS483305.1|WP_037588862.1|2116207_2117113_-|fumarylacetoacetate-hydrolase-family-protein
MKFLTFKHKDITSYGVKVKREEAVWDLRKVFADFGEEGFNPKTLLEGLQLNINVDFQEAVRKAVVKVEESAEKDDYKYSFEDIEFLPPVTPTNNVIAFGRNYKKHAEELNNKVNRLYVFTKAASSLTGDNAEIPNHKDVTDKLDYEGELGVVIGKHGEKIPRGLALDYVYGYTIINDITDRNAQKEHDQAFLSKSLTGGCPMGPYIVTKDELPLPEDVNIVTKVNNEIRQDGNTNEMILKIDELIAEISKYVALHPGDIIATGTPAGVGAGMNPPQFLQPGDEIKVTIDGIGTLTTFISEK
>NZ_LS483305.1|WP_048540115.1|2117189_2118317_-|DUF418-domain-containing-protein
MAKQRIFSIDALRGFSLLGILLMNILTFAYPYQIINPFEFFQHQDGAWFKISSLFIIASFYPIFAFLFGYGLSIMYQNSLDKGLNYYPMITRRLLFLLLLGIIHGVFIFYGDILSTYALLGLIAIIFVRLKPQYTLVALSIGIGIFVLLYLLPMILLKDVTQIESFVGLQELERVNNILSSADYVSIIGFNLKYFGMNIANAILVGPFSILPIMLFGIYAHQINWFNKIKQHKNLYMVIGVVVLILGLAIKMIQIVLEGSVTSQLMSQMIGGPIVALSYIMFFVILCEDQTVRKILTPLQSIGKLSLTTYISQSIICIIIFYGVGLNYYGKLPVLTIYIIGIVIYCVQLILSYLYLLKFKQGPLEKLWRKVTYLK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	1541060-1541077	0	1.0
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	1541140-1541157	0	1.0
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	1541220-1541237	0	1.0
NZ_LS483305_3	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	NZ_LS483305.1	1119902-1119919	0	1.0
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	1097402-1097419	1	0.944
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	1119902-1119919	1	0.944
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	2614511-2614528	1	0.944
NZ_LS483305_3	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	NZ_LS483305.1	1541060-1541077	1	0.944
NZ_LS483305_3	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	NZ_LS483305.1	1541140-1541157	1	0.944
NZ_LS483305_3	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	NZ_LS483305.1	1541220-1541237	1	0.944
NZ_LS483305_3	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	NZ_LS483305.1	2614511-2614528	1	0.944
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	768037-768054	2	0.889
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	768157-768174	2	0.889
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	1048813-1048830	2	0.889
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	1048853-1048870	2	0.889
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	1048893-1048910	2	0.889
NZ_LS483305_3	3.2\|2105735\|18\|NZ_LS483305\|CRT	2105735-2105752	18	NZ_LS483305.1	1113146-1113163	2	0.889
NZ_LS483305_3	3.3\|2105775\|18\|NZ_LS483305\|CRT	2105775-2105792	18	NZ_LS483305.1	2075128-2075145	2	0.889
NZ_LS483305_3	3.5\|2105855\|18\|NZ_LS483305\|CRT	2105855-2105872	18	NZ_LS483305.1	2075128-2075145	2	0.889
NZ_LS483305_3	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	NZ_LS483305.1	1332217-1332234	2	0.889
NZ_LS483305_3	3.8\|2105975\|18\|NZ_LS483305\|CRT	2105975-2105992	18	NZ_LS483305.1	2075128-2075145	2	0.889

1. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 1541060-1541077, mismatch: 0, identity: 1.0

taaggatacccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
******************

2. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 1541140-1541157, mismatch: 0, identity: 1.0

taaggatacccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
******************

3. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 1541220-1541237, mismatch: 0, identity: 1.0

taaggatacccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
******************

4. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to position: 1119902-1119919, mismatch: 0, identity: 1.0

taaggatatccatagtta	CRISPR spacer
taaggatatccatagtta	Protospacer
******************

5. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 1097402-1097419, mismatch: 1, identity: 0.944

tatgggcggctataatta	CRISPR spacer
tatgggcgtctataatta	Protospacer
******** *********

6. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 1119902-1119919, mismatch: 1, identity: 0.944

taaggatacccatagtta	CRISPR spacer
taaggatatccatagtta	Protospacer
********.*********

7. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 2614511-2614528, mismatch: 1, identity: 0.944

taaggatacccatagtta	CRISPR spacer
taaggatagccatagtta	Protospacer
******** *********

8. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to position: 1541060-1541077, mismatch: 1, identity: 0.944

taaggatatccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
********.*********

9. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to position: 1541140-1541157, mismatch: 1, identity: 0.944

taaggatatccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
********.*********

10. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to position: 1541220-1541237, mismatch: 1, identity: 0.944

taaggatatccatagtta	CRISPR spacer
taaggatacccatagtta	Protospacer
********.*********

11. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to position: 2614511-2614528, mismatch: 1, identity: 0.944

taaggatatccatagtta	CRISPR spacer
taaggatagccatagtta	Protospacer
******** *********

12. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 768037-768054, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tatgggggtctataatta	Protospacer
****** * *********

13. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 768157-768174, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tatgggggtctataatta	Protospacer
****** * *********

14. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 1048813-1048830, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tatggacggccataatta	Protospacer
*****.****.*******

15. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 1048853-1048870, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tatgggtcgctataatta	Protospacer
******. **********

16. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 1048893-1048910, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tatggacggccataatta	Protospacer
*****.****.*******

17. spacer 3.2|2105735|18|NZ_LS483305|CRT matches to position: 1113146-1113163, mismatch: 2, identity: 0.889

tatgggcggctataatta	CRISPR spacer
tattgacggctataatta	Protospacer
*** *.************

18. spacer 3.3|2105775|18|NZ_LS483305|CRT matches to position: 2075128-2075145, mismatch: 2, identity: 0.889

taagagcggctatattta	CRISPR spacer
taagagcggccataatta	Protospacer
**********.*** ***

19. spacer 3.5|2105855|18|NZ_LS483305|CRT matches to position: 2075128-2075145, mismatch: 2, identity: 0.889

taagagcggctatattta	CRISPR spacer
taagagcggccataatta	Protospacer
**********.*** ***

20. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to position: 1332217-1332234, mismatch: 2, identity: 0.889

taaggatacccatagtta	CRISPR spacer
taatcatacccatagtta	Protospacer
***  *************

21. spacer 3.8|2105975|18|NZ_LS483305|CRT matches to position: 2075128-2075145, mismatch: 2, identity: 0.889

taagagcggctatattta	CRISPR spacer
taagagcggccataatta	Protospacer
**********.*** ***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1089175 : 1100926

Staphylococcus_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048539508.1\|1089175_1090585_+	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.6e-133	52.4
WP_048539509.1\|1090571_1091570_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.1e-63	38.2
WP_025905546.1\|1091616_1091841_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.8e-24	67.1
WP_048539510.1\|1091851_1092637_-	hypothetical protein	NA	NA	NA	NA
WP_048539511.1\|1092703_1093168_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	8.2e-40	54.5
WP_048539806.1\|1093175_1093928_+	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.6e-77	57.1
WP_048539512.1\|1093949_1095551_-	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	1.8e-219	68.8
WP_048539513.1\|1095948_1097142_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.0e-182	79.6
WP_048539514.1\|1097702_1098614_+	hypothetical protein	A0A2H4PQQ8	Staphylococcus_phage	3.9e-70	55.0
WP_048539515.1\|1098672_1100055_+	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_048539516.1\|1100083_1100926_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.7e-105	64.0

DBSCAN-SWA_2

1116716 : 1124802

Staphylococcus_phage(85.71%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048539534.1\|1116716_1117871_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	2.6e-18	49.5
WP_048539535.1\|1118123_1119638_+	pyridine nucleotide-disulfide oxidoreductase	A0A2H4PQX2	Staphylococcus_phage	9.3e-08	42.9
WP_048539536.1\|1120398_1121445_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.1e-91	47.7
WP_048539537.1\|1121449_1122082_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.8e-54	51.4
WP_048539538.1\|1122093_1123266_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-139	62.1
WP_048539539.1\|1123286_1123757_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.3e-56	81.2
WP_048539540.1\|1123797_1124802_-	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	1.9e-105	57.5

DBSCAN-SWA_3

1128829 : 1136098

Staphylococcus_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048539545.1\|1128829_1129387_-	methyltransferase domain-containing protein	A0A2H4PQV0	Staphylococcus_phage	3.5e-53	56.8
WP_048539546.1\|1129383_1130343_-	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	3.8e-63	80.0
WP_048539547.1\|1130462_1131638_+	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	4.2e-125	57.6
WP_048539548.1\|1131928_1134313_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	79.3
WP_048539549.1\|1134334_1134646_+	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	2.3e-30	62.1
WP_048539550.1\|1134838_1136098_-	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	5.0e-31	62.9

DBSCAN-SWA_4

1265701 : 1274743

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048539644.1\|1265701_1266697_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	2.6e-06	29.9
WP_048539645.1\|1266713_1267739_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_048539646.1\|1267754_1268894_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.1
WP_025904259.1\|1268906_1269170_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.8e-06	40.9
WP_048539647.1\|1269339_1271631_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.6e-30	34.0
WP_048539648.1\|1271930_1274225_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.1e-68	30.1
WP_025904256.1\|1274224_1274743_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	3.3e-29	47.9

DBSCAN-SWA_5

1800575 : 1877860

Staphylococcus_phage(92.98%)

holin,head,tRNA,integrase,portal,terminase,protease,tail,capsid

attL 1834705:1834747|attR 1876153:1876195

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048542444.1\|1800575_1802630_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_048542443.1\|1803042_1803972_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_048542441.1\|1804260_1807011_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	3.0e-89	26.5
WP_025904594.1\|1807212_1807797_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_048542439.1\|1807815_1808589_-	RNA-binding protein	NA	NA	NA	NA
WP_048542438.1\|1808660_1808957_-	YggT family protein	NA	NA	NA	NA
WP_025904597.1\|1808970_1809546_-	cell division protein SepF	NA	NA	NA	NA
WP_048542436.1\|1809557_1810229_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_048542433.1\|1810237_1811029_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_025904600.1\|1811088_1812246_-	cell division protein FtsZ	NA	NA	NA	NA
WP_048542432.1\|1812274_1813648_-	cell division protein FtsA	NA	NA	NA	NA
WP_048542775.1\|1813757_1814555_-	FtsQ-type POTRA domain-containing protein	NA	NA	NA	NA
WP_048542430.1\|1814728_1816078_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_048542428.1\|1816079_1817045_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_048542426.1\|1817089_1819345_-	penicillin-binding protein	NA	NA	NA	NA
WP_048542424.1\|1819331_1819712_-	cell division protein FtsL	NA	NA	NA	NA
WP_048542422.1\|1819731_1820667_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_048542420.1\|1820678_1821110_-	division/cell wall cluster transcriptional repressor MraZ	NA	NA	NA	NA
WP_048542418.1\|1821255_1822872_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
WP_048542415.1\|1823006_1823453_+	N-acetyltransferase	NA	NA	NA	NA
WP_048542414.1\|1823501_1824494_-	YdcF family protein	NA	NA	NA	NA
WP_048542411.1\|1824659_1825718_+	hypothetical protein	NA	NA	NA	NA
WP_080964700.1\|1826053_1829335_-	hypothetical protein	NA	NA	NA	NA
WP_037559882.1\|1829570_1829807_-	hypothetical protein	NA	NA	NA	NA
WP_053076882.1\|1830533_1830863_+	helix-turn-helix transcriptional regulator	X2CXD8	Lactobacillus_phage	5.5e-06	44.4
WP_155403653.1\|1830990_1831161_+	hypothetical protein	NA	NA	NA	NA
WP_048542409.1\|1831423_1832590_-	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_048542407.1\|1833516_1834089_+	GrpB family protein	NA	NA	NA	NA
WP_048542406.1\|1834116_1834554_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
1834705:1834747	attL	NA	NA	NA	NA
WP_048542404.1\|1834892_1835303_+	YolD-like family protein	A0A1Q1PW34	Staphylococcus_phage	3.7e-76	100.0
WP_142383034.1\|1835346_1835814_+	hypothetical protein	A0A1Q1PW26	Staphylococcus_phage	5.9e-78	100.0
WP_048542400.1\|1835968_1836469_+	ATP-binding protein	A0A1Q1PW45	Staphylococcus_phage	5.0e-91	100.0
WP_048542398.1\|1836527_1837085_-	hypothetical protein	A0A1Q1PW40	Staphylococcus_phage	2.0e-93	100.0
WP_048542396.1\|1837096_1838047_-	DUF4868 domain-containing protein	A0A1Q1PW39	Staphylococcus_phage	6.4e-172	100.0
WP_155403652.1\|1838737_1838914_-	hypothetical protein	A0A1Q1PW37	Staphylococcus_phage	1.1e-24	100.0
WP_053076881.1\|1839093_1839963_-	N-acetylmuramoyl-L-alanine amidase	A0A1Q1PW31	Staphylococcus_phage	4.6e-177	100.0
WP_048542394.1\|1840038_1840299_-\|holin	phage holin	A0A1Q1PW49	Staphylococcus_phage	1.3e-39	100.0
WP_048542392.1\|1840311_1840698_-	hypothetical protein	A0A1Q1PW36	Staphylococcus_phage	1.4e-64	100.0
WP_048542767.1\|1840697_1841141_-	hypothetical protein	A0A1Q1PW24	Staphylococcus_phage	6.6e-71	100.0
WP_048542390.1\|1841199_1841487_-	hypothetical protein	A0A1Q1PW19	Staphylococcus_phage	3.9e-48	100.0
WP_048542389.1\|1841527_1841689_-	hypothetical protein	A0A1Q1PW33	Staphylococcus_phage	1.6e-19	100.0
WP_053076880.1\|1841688_1845492_-	hypothetical protein	A0A1Q1PW30	Staphylococcus_phage	0.0e+00	99.8
WP_048542388.1\|1845507_1847028_-	hypothetical protein	A0A1Q1PW27	Staphylococcus_phage	1.1e-298	100.0
WP_048542387.1\|1847042_1852040_-\|tail	phage tail tape measure protein	A0A1Q1PW35	Staphylococcus_phage	0.0e+00	100.0
WP_048542385.1\|1852290_1852740_-	hypothetical protein	A0A1Q1PW23	Staphylococcus_phage	9.7e-54	100.0
WP_048542383.1\|1852815_1853532_-	hypothetical protein	A0A1Q1PW21	Staphylococcus_phage	1.2e-130	100.0
WP_048542762.1\|1853544_1853922_-	DUF806 family protein	A0A1Q1PW41	Staphylococcus_phage	9.3e-66	99.2
WP_048542381.1\|1853921_1854299_-	HK97 gp10 family phage protein	A0A1Q1PW28	Staphylococcus_phage	4.3e-63	100.0
WP_048542379.1\|1854298_1854631_-\|head,tail	head-tail adaptor protein	A0A1Q1PW14	Staphylococcus_phage	4.3e-59	100.0
WP_048542377.1\|1854620_1854953_-\|head,tail	phage head-tail adapter protein	A0A1Q1PVW9	Staphylococcus_phage	1.9e-59	100.0
WP_048542375.1\|1854964_1855159_-	hypothetical protein	A0A1Q1PW25	Staphylococcus_phage	7.4e-27	100.0
WP_048542373.1\|1855201_1856428_-\|capsid	phage major capsid protein	A0A1Q1PW20	Staphylococcus_phage	3.0e-198	100.0
WP_080964693.1\|1856537_1857080_-\|head,protease	HK97 family phage prohead protease	A0A1Q1PVX3	Staphylococcus_phage	7.7e-98	100.0
WP_048542369.1\|1857126_1858392_-\|portal	phage portal protein	A0A1Q1PW22	Staphylococcus_phage	6.0e-242	100.0
WP_048542367.1\|1858397_1858598_-	hypothetical protein	A0A1Q1PW17	Staphylococcus_phage	1.9e-25	100.0
WP_048542365.1\|1858609_1860337_-	hypothetical protein	A0A1Q1PW18	Staphylococcus_phage	0.0e+00	100.0
WP_048542363.1\|1860320_1860803_-\|terminase	phage terminase small subunit P27 family	A0A1Q1PVW3	Staphylococcus_phage	7.4e-84	100.0
WP_103354181.1\|1860972_1861320_-	HNH endonuclease	A0A1Q1PW15	Staphylococcus_phage	1.6e-64	100.0
WP_070369253.1\|1861461_1861827_-	hypothetical protein	A0A1Q1PVV6	Staphylococcus_phage	3.8e-48	100.0
WP_070373048.1\|1861896_1862355_-	nucleoside triphosphate pyrophosphohydrolase family protein	A0A1Q1PVZ6	Staphylococcus_phage	1.1e-81	100.0
WP_048542359.1\|1862341_1862551_-	hypothetical protein	A0A1Q1PW12	Staphylococcus_phage	7.0e-31	100.0
WP_053076879.1\|1862544_1862760_-	hypothetical protein	A0A1Q1PW05	Staphylococcus_phage	8.7e-37	100.0
WP_048542357.1\|1862820_1863219_-	hypothetical protein	A0A1Q1PW07	Staphylococcus_phage	1.8e-67	100.0
WP_048542355.1\|1863218_1863641_-	RusA family crossover junction endodeoxyribonuclease	A0A1Q1PW16	Staphylococcus_phage	1.9e-75	100.0
WP_048542353.1\|1863637_1864345_-	hypothetical protein	A0A1Q1PW10	Staphylococcus_phage	1.2e-63	100.0
WP_048542352.1\|1864328_1865258_-	DnaD domain protein	A0A1Q1PW08	Staphylococcus_phage	1.3e-124	100.0
WP_048542350.1\|1865290_1865773_-	single-stranded DNA-binding protein	A0A1Q1PW11	Staphylococcus_phage	1.5e-84	100.0
WP_080964691.1\|1865773_1866376_-	MBL fold metallo-hydrolase	A0A1Q1PW06	Staphylococcus_phage	1.0e-111	100.0
WP_048542348.1\|1866471_1867380_-	recombinase	A0A1Q1PVZ0	Staphylococcus_phage	3.2e-157	100.0
WP_048542347.1\|1867443_1867914_+	DUF2321 domain-containing protein	A0A1Q1PVY6	Staphylococcus_phage	7.0e-87	99.4
WP_048542345.1\|1868076_1868412_-	hypothetical protein	A0A1Q1PW02	Staphylococcus_phage	3.1e-57	100.0
WP_048542343.1\|1868408_1870361_-	AAA family ATPase	A0A1Q1PVZ7	Staphylococcus_phage	0.0e+00	100.0
WP_048542342.1\|1870448_1870754_-	DUF1108 family protein	A0A1Q1PVZ5	Staphylococcus_phage	6.1e-52	100.0
WP_048542340.1\|1870754_1870934_-	hypothetical protein	A0A1Q1PW03	Staphylococcus_phage	1.1e-24	100.0
WP_048542338.1\|1870930_1871158_-	DUF771 domain-containing protein	A0A1Q1PW00	Staphylococcus_phage	4.9e-38	100.0
WP_048542335.1\|1871258_1871471_-	hypothetical protein	A0A1Q1PVZ9	Staphylococcus_phage	3.7e-32	100.0
WP_048542334.1\|1871519_1871729_+	hypothetical protein	A0A2H4JAT7	uncultured_Caudovirales_phage	2.2e-16	60.3
WP_048542332.1\|1871840_1872623_-	phage antirepressor KilAC domain-containing protein	A0A1Q1PVZ8	Staphylococcus_phage	2.6e-147	100.0
WP_048542330.1\|1872656_1872896_-	helix-turn-helix transcriptional regulator	A0A1Q1PVY0	Staphylococcus_phage	4.8e-36	100.0
WP_048542328.1\|1873040_1873661_+	helix-turn-helix domain-containing protein	A0A1Q1PVX8	Staphylococcus_phage	7.0e-111	100.0
WP_048542327.1\|1873719_1874691_+	hypothetical protein	A0A1Q1PVZ4	Staphylococcus_phage	1.2e-178	100.0
WP_048542325.1\|1874664_1874853_-	hypothetical protein	A0A1Q1PVY5	Staphylococcus_phage	2.7e-26	100.0
WP_048542323.1\|1875024_1876053_+\|integrase	site-specific integrase	A0A1Q1PVY8	Staphylococcus_phage	3.8e-194	99.7
WP_037587508.1\|1876374_1876590_-	hypothetical protein	NA	NA	NA	NA
1876153:1876195	attR	NA	NA	NA	NA
WP_048542321.1\|1876772_1877279_-	metallophosphoesterase	NA	NA	NA	NA
WP_048542319.1\|1877275_1877860_-	XTP/dITP diphosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	8.0e-16	33.7

DBSCAN-SWA_6

1957791 : 1966262

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048542190.1\|1957791_1958358_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-28	39.6
WP_048542188.1\|1958354_1959389_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.9e-68	44.3
WP_048542184.1\|1959372_1960869_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.0e-43	31.5
WP_048542183.1\|1960847_1963037_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	40.0
WP_048542181.1\|1963029_1963701_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_048542179.1\|1963700_1963961_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_048542178.1\|1963962_1964664_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	7.8e-42	39.1
WP_048542176.1\|1964665_1965793_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_025905207.1\|1965779_1966262_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	8.9e-21	42.0

DBSCAN-SWA_7

2166263 : 2173597

Staphylococcus_phage(50.0%)

bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_048540175.1\|2166263_2166896_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.5e-23	37.3
WP_048540177.1\|2166892_2167255_-	YxeA family protein	NA	NA	NA	NA
WP_048540179.1\|2167254_2169258_-	hypothetical protein	NA	NA	NA	NA
WP_048540181.1\|2169283_2169577_-\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_048540182.1\|2169831_2171085_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1X9I9G7	Staphylococcus_phage	1.6e-74	74.1
WP_025904389.1\|2171105_2171426_-	hypothetical protein	Q4ZD59	Staphylococcus_phage	1.9e-27	67.5
WP_025904388.1\|2171568_2171898_+	helix-turn-helix transcriptional regulator	H9A0K4	Staphylococcus_phage	4.1e-09	38.6
WP_048540184.1\|2171929_2172394_+	toxin	A1BTY5	Staphylococcus_virus	1.8e-39	52.3
WP_048540185.1\|2172448_2173597_-	galactonate dehydratase	Q6A202	Oenococcus_phage	2.6e-63	36.8

DBSCAN-SWA_8

2232816 : 2239981

Staphylococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075577747.1\|2232816_2232969_-	hypothetical protein	A0A1Q1PVW7	Staphylococcus_phage	1.1e-12	78.0
WP_053076866.1\|2233808_2234123_+	hypothetical protein	A0A1Q1PW34	Staphylococcus_phage	6.8e-30	79.1
WP_167401695.1\|2234123_2234264_-	hypothetical protein	NA	NA	NA	NA
WP_153653758.1\|2234485_2234662_-	hypothetical protein	A0A1Q1PW37	Staphylococcus_phage	6.5e-22	89.7
WP_048539896.1\|2234794_2235019_-	hypothetical protein	NA	NA	NA	NA
WP_088592741.1\|2235336_2236143_-	CHAP domain-containing protein	A0A1W6JQB6	Staphylococcus_phage	2.4e-63	33.2
WP_048539897.1\|2237154_2237622_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	3.3e-57	77.2
WP_048539898.1\|2237632_2239981_-	ribonuclease R	Q0GXV6	Lactococcus_phage	1.0e-90	38.1

DBSCAN-SWA_9

2289714 : 2302455

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162841905.1\|2289714_2290671_-	iron chelate uptake ABC transporter family permease subunit	A0A2H4IY97	uncultured_Caudovirales_phage	1.0e-113	67.6
WP_048539936.1\|2290812_2291229_-	FixH family protein	NA	NA	NA	NA
WP_048539937.1\|2291378_2292350_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	2.6e-160	85.4
WP_048539938.1\|2292378_2294484_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	84.0
WP_025905413.1\|2294446_2294845_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	3.0e-38	58.3
WP_048539939.1\|2295220_2296105_+	DMT family transporter	NA	NA	NA	NA
WP_048539940.1\|2296104_2296605_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.0e-48	67.9
WP_048539941.1\|2296899_2298414_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.2e-66	34.9
WP_048539942.1\|2299199_2300702_+	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	4.8e-65	35.6
WP_048539943.1\|2300741_2301323_-	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_048539944.1\|2301387_2302455_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-13	22.8

Anti-CRISPR protein detection

Acr_ID: NZ_LS483305.1|WP_048539539.1|1123286_1123757_+|6,7-dimethyl-8-ribityllumazine-synthase

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483305.1|WP_048539539.1|1123286_1123757_+|6,7-dimethyl-8-ribityllumazine-synthase

1123286_1123757_+

156 aa aa

1116716-1124802

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_LS483305_3	Orphan	3.6\|2105895\|18\|NZ_LS483305\|CRT	2105895-2105912	18	1119919-1119902	1
NZ_LS483305_3	Orphan	3.9\|2106015\|18\|NZ_LS483305\|CRT	2106015-2106032	18	1119919-1119902	0

1. spacer 3.6|2105895|18|NZ_LS483305|CRT matches to NZ_LS483305 position: 1119919-1119902, mismatch: 1

taaggatacccatagtta	CRISPR spacer
taaggatatccatagtta	Protospacer
********.*********

2. spacer 3.9|2106015|18|NZ_LS483305|CRT matches to NZ_LS483305 position: 1119919-1119902, mismatch: 0

taaggatatccatagtta	CRISPR spacer
taaggatatccatagtta	Protospacer
******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483305

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information