CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483314	Staphylococcus aureus strain NCTC3761 chromosome 1	8 crisprs	cas3,DEDDh,DinG,csa3,WYL	5	1	12	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483314_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_1

142190-142271

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_1

>merge|NZ_LS483314|1|142190-142271|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_LS483314|1|1|142190-142271|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_000590860.1\|143570_144311_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NZ_LS483314.1\|WP_000356963.1\|142334_142538_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_076749343.1\|150957_158133_+\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|237108
NZ_LS483314.1\|WP_000480603.1\|137804_138131_-\|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968
NZ_LS483314.1\|WP_001013481.1\|141081_142041_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NZ_LS483314.1\|WP_001236999.1\|138137_138521_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NZ_LS483314.1\|WP_000706137.1\|147849_148875_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
NZ_LS483314.1\|WP_000239649.1\|131335_132541_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000826655.1\|144324_145299_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NZ_LS483314.1\|WP_000779494.1\|135255_136518_+\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
NZ_LS483314.1\|WP_000290396.1\|138947_140435_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NZ_LS483314.1\|WP_001092004.1\|147317_147677_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|227896
NZ_LS483314.1\|WP_000171645.1\|146069_147101_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NZ_LS483314.1\|WP_000197961.1\|145295_146057_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NZ_LS483314.1\|WP_000171919.1\|142716_143229_+\|DUF4242-domain-containing-protein	unknown	unknown	gnl\|CDD\|379428
NZ_LS483314.1\|WP_000826862.1\|149260_150511_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NZ_LS483314.1\|WP_000825098.1\|133757_134315_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|225059
NZ_LS483314.1\|WP_111688513.1\|134314_135202_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl\|CDD\|187543
NZ_LS483314.1\|WP_001291017.1\|132541_133747_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340825
NZ_LS483314.1\|WP_000723455.1\|136594_137740_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000590860.1\|143570_144311_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.48266e-112
NZ_LS483314.1\|WP_076749343.1\|150957_158133_+\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NZ_LS483314.1\|WP_000480603.1\|137804_138131_-\|staphylobilin-forming-heme-oxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
NZ_LS483314.1\|WP_001013481.1\|141081_142041_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.08716e-108
NZ_LS483314.1\|WP_001236999.1\|138137_138521_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	7.54946e-41
NZ_LS483314.1\|WP_000706137.1\|147849_148875_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NZ_LS483314.1\|WP_000826655.1\|144324_145299_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.03649e-50
NZ_LS483314.1\|WP_000779494.1\|135255_136518_+\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NZ_LS483314.1\|WP_000290396.1\|138947_140435_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NZ_LS483314.1\|WP_001092004.1\|147317_147677_+\|DUF2294-domain-containing-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NZ_LS483314.1\|WP_000171645.1\|146069_147101_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
NZ_LS483314.1\|WP_000197961.1\|145295_146057_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NZ_LS483314.1\|WP_000171919.1\|142716_143229_+\|DUF4242-domain-containing-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NZ_LS483314.1\|WP_000826862.1\|149260_150511_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NZ_LS483314.1\|WP_000825098.1\|133757_134315_+\|sugar-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87
NZ_LS483314.1\|WP_111688513.1\|134314_135202_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.07051e-118
NZ_LS483314.1\|WP_001291017.1\|132541_133747_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	1.1999e-72
NZ_LS483314.1\|WP_000723455.1\|136594_137740_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0

>NZ_LS483314.1|WP_001013481.1|141081_142041_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILAAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NZ_LS483314.1|WP_000290396.1|138947_140435_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDKEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NZ_LS483314.1|WP_001236999.1|138137_138521_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIAFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NZ_LS483314.1|WP_000480603.1|137804_138131_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NZ_LS483314.1|WP_000723455.1|136594_137740_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLAGLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERILITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>NZ_LS483314.1|WP_000779494.1|135255_136518_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEIYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NZ_LS483314.1|WP_111688513.1|134314_135202_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQLHRKTVLINMPSMLNKYFNKLSVFRKLFGNLIYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NZ_LS483314.1|WP_000825098.1|133757_134315_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NZ_LS483314.1|WP_001291017.1|132541_133747_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKALVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NZ_LS483314.1|WP_000239649.1|131335_132541_+|hypothetical-protein
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLTQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITIIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>NZ_LS483314.1|WP_000356963.1|142334_142538_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NZ_LS483314.1|WP_000171919.1|142716_143229_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NZ_LS483314.1|WP_000590860.1|143570_144311_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSLKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>NZ_LS483314.1|WP_000826655.1|144324_145299_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIIIGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NZ_LS483314.1|WP_000197961.1|145295_146057_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NZ_LS483314.1|WP_000171645.1|146069_147101_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NZ_LS483314.1|WP_001092004.1|147317_147677_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NZ_LS483314.1|WP_000706137.1|147849_148875_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKALGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSTSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NZ_LS483314.1|WP_000826862.1|149260_150511_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NZ_LS483314.1|WP_076749343.1|150957_158133_+|amino-acid-adenylation-domain-containing-protein
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDVTPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHQNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPETIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSELNVAQLRQAVQRLIARHEILRTQYIVVDDEVRQRIVADVAVDFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYIINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEAVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPKKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPAQLQQLINKHRVTVASIPLQMCSVMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENAILAIRGISDCVVTVSHFDTHDILNAYYVGEQQMEQDLKQYLNDHLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMHQNQQSLVALPDNLSELQKIVMSRYNLGVLEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: NZ_LS483314_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_2

265439-265579

Orphan

Consensus_repeat	Method
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_2

>merge|NZ_LS483314|2|265439-265579|CRISPRCasFinder
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG

>NZ_LS483314|2|2|265439-265579|CRISPRCasFinder
GGGCCCCAACACAAAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG	CGGAAAGTCAGCATACAATAATGTGCAAGTTGGCG
GGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGTAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_000645454.1\|260167_260908_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495
NZ_LS483314.1\|WP_000164001.1\|263925_265362_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NZ_LS483314.1\|WP_000975368.1\|255626_257348_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|376098
NZ_LS483314.1\|WP_000608831.1\|257491_258166_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NZ_LS483314.1\|WP_000029204.1\|268202_269084_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NZ_LS483314.1\|WP_000066933.1\|263118_263910_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NZ_LS483314.1\|WP_000570077.1\|274727_275387_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LS483314.1\|WP_000240920.1\|253905_255594_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NZ_LS483314.1\|WP_000607067.1\|261456_262158_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NZ_LS483314.1\|WP_000182745.1\|266841_267756_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NZ_LS483314.1\|WP_000337372.1\|272407_273400_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NZ_LS483314.1\|WP_000757894.1\|269315_270314_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NZ_LS483314.1\|WP_001789860.1\|266609_266744_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001792906.1\|261020_261464_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NZ_LS483314.1\|WP_000736795.1\|273725_274676_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|366703
NZ_LS483314.1\|WP_001066543.1\|270797_272174_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NZ_LS483314.1\|WP_031874565.1\|258410_260165_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NZ_LS483314.1\|WP_042727592.1\|267783_268188_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NZ_LS483314.1\|WP_000922332.1\|262265_262970_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NZ_LS483314.1\|WP_000031267.1\|265829_266591_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000645454.1\|260167_260908_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	9.61135e-152
NZ_LS483314.1\|WP_000164001.1\|263925_265362_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NZ_LS483314.1\|WP_000975368.1\|255626_257348_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	4.75037e-35
NZ_LS483314.1\|WP_000608831.1\|257491_258166_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154
NZ_LS483314.1\|WP_000029204.1\|268202_269084_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
NZ_LS483314.1\|WP_000066933.1\|263118_263910_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	1.8481e-54
NZ_LS483314.1\|WP_000570077.1\|274727_275387_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.07951e-65
NZ_LS483314.1\|WP_000240920.1\|253905_255594_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NZ_LS483314.1\|WP_000607067.1\|261456_262158_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NZ_LS483314.1\|WP_000182745.1\|266841_267756_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	6.00205e-143
NZ_LS483314.1\|WP_000337372.1\|272407_273400_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	1.22357e-151
NZ_LS483314.1\|WP_000757894.1\|269315_270314_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.35556e-100
NZ_LS483314.1\|WP_001066543.1\|270797_272174_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.20037e-31
NZ_LS483314.1\|WP_001792906.1\|261020_261464_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	8.44339e-64
NZ_LS483314.1\|WP_000736795.1\|273725_274676_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	6.32575e-32
NZ_LS483314.1\|WP_031874565.1\|258410_260165_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NZ_LS483314.1\|WP_042727592.1\|267783_268188_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	2.3935e-68
NZ_LS483314.1\|WP_000922332.1\|262265_262970_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	1.3822e-62
NZ_LS483314.1\|WP_000031267.1\|265829_266591_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.03413e-27

>NZ_LS483314.1|WP_000164001.1|263925_265362_+|6-phospho-beta-glucosidase
MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEGVPNEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NZ_LS483314.1|WP_000066933.1|263118_263910_+|PTS-glucose-transporter-subunit-IIA
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTSYTPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLVSMIVPTKHAVGIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDHVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NZ_LS483314.1|WP_000922332.1|262265_262970_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSNFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEMATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NZ_LS483314.1|WP_000607067.1|261456_262158_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NZ_LS483314.1|WP_001792906.1|261020_261464_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NZ_LS483314.1|WP_000645454.1|260167_260908_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSANAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPTYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NZ_LS483314.1|WP_031874565.1|258410_260165_+|sensor-histidine-kinase
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDMLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NZ_LS483314.1|WP_000608831.1|257491_258166_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NZ_LS483314.1|WP_000975368.1|255626_257348_+|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase
MMKFSVIVPTYNSEKYMTELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NZ_LS483314.1|WP_000240920.1|253905_255594_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NZ_LS483314.1|WP_000031267.1|265829_266591_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED
>NZ_LS483314.1|WP_001789860.1|266609_266744_+|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
>NZ_LS483314.1|WP_000182745.1|266841_267756_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTTEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFIVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NZ_LS483314.1|WP_042727592.1|267783_268188_-|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIGVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NZ_LS483314.1|WP_000029204.1|268202_269084_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NZ_LS483314.1|WP_000757894.1|269315_270314_-|LacI-family-DNA-binding-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSSLMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NZ_LS483314.1|WP_001066543.1|270797_272174_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGDHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSIICLSIFSITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTSLQPSQYIIAVVIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYTPSVAATVTFIVSIILMMLGSLSAYMIIPKTVKS
>NZ_LS483314.1|WP_000337372.1|272407_273400_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLNWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NZ_LS483314.1|WP_000736795.1|273725_274676_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNSPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
>NZ_LS483314.1|WP_000570077.1|274727_275387_-|ABC-transporter-ATP-binding-protein
MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLLRMVAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENINFFKSLCKNPINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGQPRILILDEPTVGIDLKSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWAYTYY

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Click the colored protein region to show detailed information

Crispr_ID: NZ_LS483314_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_3

689175-689273

Orphan

Consensus_repeat	Method
AAGAGCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_3

>merge|NZ_LS483314|3|689175-689273|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGGACAAAGGAATACAGTTGGATGCTAACGCACCAACTGCATAAGAGCCCCTAATTAATAAATTAAAAGGGG

>NZ_LS483314|3|3|689175-689273|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGG	ACAAAGGAATACAGTTGGATGCTAACGCACCAACTGCAT
AAGAGCCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_000148828.1\|694532_694991_-\|YaiI/YqxD-family-protein	unknown	unknown	gnl\|CDD\|178882
NZ_LS483314.1\|WP_000545116.1\|692947_693247_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001259679.1\|691910_692354_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_LS483314.1\|WP_000733433.1\|692420_692810_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_111688558.1\|691094_691784_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001090985.1\|685372_685732_+\|HTH-type-transcriptional-regulator-SarX	unknown	unknown	gnl\|CDD\|130944
NZ_LS483314.1\|WP_000358498.1\|694993_695677_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234750
NZ_LS483314.1\|WP_000833486.1\|686637_687111_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226072
NZ_LS483314.1\|WP_001789973.1\|687202_687319_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000687412.1\|688223_689090_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_LS483314.1\|WP_000081602.1\|681735_682380_+\|Bax-inhibitor-1-family-protein	unknown	unknown	gnl\|CDD\|223742
NZ_LS483314.1\|WP_000152582.1\|690507_690996_+\|DUF456-domain-containing-protein	unknown	unknown	gnl\|CDD\|225395
NZ_LS483314.1\|WP_111688556.1\|687463_688108_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|225188
NZ_LS483314.1\|WP_000532966.1\|685921_686638_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|237084
NZ_LS483314.1\|WP_000638621.1\|693326_693869_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_LS483314.1\|WP_061738730.1\|693964_694531_-\|TIGR00730-family-Rossman-fold-protein	unknown	unknown	gnl\|CDD\|224527
NZ_LS483314.1\|WP_001129752.1\|683076_685227_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NZ_LS483314.1\|WP_000731641.1\|680577_681375_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_LS483314.1\|WP_000367063.1\|689290_690511_+\|sugar-efflux-transporter	unknown	unknown	gnl\|CDD\|341024
NZ_LS483314.1\|WP_000120367.1\|678981_679989_+\|inorganic-phosphate-transporter	unknown	unknown	gnl\|CDD\|376541

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000358498.1\|694993_695677_-\|hypothetical-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0.000491798
NZ_LS483314.1\|WP_001259679.1\|691910_692354_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.77401e-13
NZ_LS483314.1\|WP_000148828.1\|694532_694991_-\|YaiI/YqxD-family-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	1.18273e-77
NZ_LS483314.1\|WP_001090985.1\|685372_685732_+\|HTH-type-transcriptional-regulator-SarX	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.54609e-22
NZ_LS483314.1\|WP_000833486.1\|686637_687111_+\|cupin-domain-containing-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	7.22926e-75
NZ_LS483314.1\|WP_061738730.1\|693964_694531_-\|TIGR00730-family-Rossman-fold-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	5.44842e-61
NZ_LS483314.1\|WP_000687412.1\|688223_689090_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.04787e-39
NZ_LS483314.1\|WP_000081602.1\|681735_682380_+\|Bax-inhibitor-1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	1.16188e-32
NZ_LS483314.1\|WP_000152582.1\|690507_690996_+\|DUF456-domain-containing-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	4.76789e-44
NZ_LS483314.1\|WP_111688556.1\|687463_688108_+\|DUF402-domain-containing-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	6.61513e-90
NZ_LS483314.1\|WP_000532966.1\|685921_686638_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
NZ_LS483314.1\|WP_000638621.1\|693326_693869_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.26713e-28
NZ_LS483314.1\|WP_001129752.1\|683076_685227_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.12683e-20
NZ_LS483314.1\|WP_000731641.1\|680577_681375_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.44834e-40
NZ_LS483314.1\|WP_000367063.1\|689290_690511_+\|sugar-efflux-transporter	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30756e-101
NZ_LS483314.1\|WP_000120367.1\|678981_679989_+\|inorganic-phosphate-transporter	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	1.90489e-104

>NZ_LS483314.1|WP_000687412.1|688223_689090_+|LysR-family-transcriptional-regulator
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>NZ_LS483314.1|WP_111688556.1|687463_688108_+|DUF402-domain-containing-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLYVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKNHQKPQNKTNIEKSKQIKPKQYNQTKNHQQQKKN
>NZ_LS483314.1|WP_001789973.1|687202_687319_+|hypothetical-protein
MLQLFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN
>NZ_LS483314.1|WP_000833486.1|686637_687111_+|cupin-domain-containing-protein
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYVVPKGTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>NZ_LS483314.1|WP_000532966.1|685921_686638_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>NZ_LS483314.1|WP_001090985.1|685372_685732_+|HTH-type-transcriptional-regulator-SarX
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
>NZ_LS483314.1|WP_001129752.1|683076_685227_+|helix-turn-helix-transcriptional-regulator
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>NZ_LS483314.1|WP_000081602.1|681735_682380_+|Bax-inhibitor-1-family-protein
MSQNTNHSYYHQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>NZ_LS483314.1|WP_000731641.1|680577_681375_-|LysM-peptidoglycan-binding-domain-containing-protein
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNSSNTSPQAGSASSHTVQAGESLNIIASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>NZ_LS483314.1|WP_000120367.1|678981_679989_+|inorganic-phosphate-transporter
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLACLLFYILNLFF
>NZ_LS483314.1|WP_000367063.1|689290_690511_+|sugar-efflux-transporter
MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>NZ_LS483314.1|WP_000152582.1|690507_690996_+|DUF456-domain-containing-protein
MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALLIN
>NZ_LS483314.1|WP_111688558.1|691094_691784_-|hypothetical-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMTNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKNGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>NZ_LS483314.1|WP_001259679.1|691910_692354_+|GNAT-family-N-acetyltransferase
MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISSTIHKNNLPMISLNKDLGYQVSHVKMYKDID
>NZ_LS483314.1|WP_000733433.1|692420_692810_+|hypothetical-protein
MKKLIISIMAVMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKEASQDKQSKDQIKSSDKDNHKKPTSTDKDQKANDKHQS
>NZ_LS483314.1|WP_000545116.1|692947_693247_+|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>NZ_LS483314.1|WP_000638621.1|693326_693869_+|GNAT-family-N-acetyltransferase
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKETHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>NZ_LS483314.1|WP_061738730.1|693964_694531_-|TIGR00730-family-Rossman-fold-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMDAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>NZ_LS483314.1|WP_000148828.1|694532_694991_-|YaiI/YqxD-family-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
>NZ_LS483314.1|WP_000358498.1|694993_695677_-|hypothetical-protein
MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKVASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKDADKMNKILQKNIEKRHKEEQKAREKNEIQRIKDMKKSQKYEEKAGLTPNKLDEKTEKKGDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQQNKENNTEA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_LS483314_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_4

742069-742151

Orphan

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_4

>merge|NZ_LS483314|4|742069-742151|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NZ_LS483314|4|4|742069-742151|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_000692521.1\|747818_748217_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NZ_LS483314.1\|WP_000180991.1\|738270_739785_+\|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl\|CDD\|270328
NZ_LS483314.1\|WP_000876318.1\|752081_753053_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226965
NZ_LS483314.1\|WP_000197275.1\|741377_741920_+\|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl\|CDD\|226895
NZ_LS483314.1\|WP_000930014.1\|745631_746132_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|223851
NZ_LS483314.1\|WP_000022321.1\|729714_730719_+\|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224895
NZ_LS483314.1\|WP_001790169.1\|728726_728933_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_031797439.1\|743606_743708_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001068497.1\|746151_747018_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NZ_LS483314.1\|WP_000589260.1\|737300_738278_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NZ_LS483314.1\|WP_111688562.1\|748179_750285_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|236069
NZ_LS483314.1\|WP_000098285.1\|731192_733133_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl\|CDD\|224287
NZ_LS483314.1\|WP_000193751.1\|743785_745291_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|225646
NZ_LS483314.1\|WP_042727613.1\|729020_729731_+\|allophanate-hydrolase-subunit-1	unknown	unknown	gnl\|CDD\|224960
NZ_LS483314.1\|WP_000983677.1\|735297_737079_+\|DNA-helicase-RecQ	unknown	unknown	gnl\|CDD\|273594
NZ_LS483314.1\|WP_000525103.1\|733402_735286_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_LS483314.1\|WP_000499195.1\|751887_752043_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000562498.1\|750402_751374_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NZ_LS483314.1\|WP_111688560.1\|740024_741083_+\|histidinol-phosphate-transaminase	unknown	unknown	gnl\|CDD\|235106
NZ_LS483314.1\|WP_000429006.1\|742599_743517_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|224513

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000692521.1\|747818_748217_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NZ_LS483314.1\|WP_000180991.1\|738270_739785_+\|ABC-transporter-permease/substrate-binding-protein	gnl\|CDD\|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NZ_LS483314.1\|WP_000876318.1\|752081_753053_+\|ABC-transporter-permease	gnl\|CDD\|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NZ_LS483314.1\|WP_000197275.1\|741377_741920_+\|5'-3'-deoxyribonucleotidase	gnl\|CDD\|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	1.69885e-107
NZ_LS483314.1\|WP_000930014.1\|745631_746132_-\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NZ_LS483314.1\|WP_000022321.1\|729714_730719_+\|biotin-dependent-carboxyltransferase-family-protein	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	3.65343e-143
NZ_LS483314.1\|WP_000193751.1\|743785_745291_-\|peptide-MFS-transporter	gnl\|CDD\|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NZ_LS483314.1\|WP_000589260.1\|737300_738278_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	4.80291e-155
NZ_LS483314.1\|WP_111688562.1\|748179_750285_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0
NZ_LS483314.1\|WP_000098285.1\|731192_733133_+\|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NZ_LS483314.1\|WP_001068497.1\|746151_747018_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.8323e-10
NZ_LS483314.1\|WP_042727613.1\|729020_729731_+\|allophanate-hydrolase-subunit-1	gnl\|CDD\|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	6.58993e-93
NZ_LS483314.1\|WP_000983677.1\|735297_737079_+\|DNA-helicase-RecQ	gnl\|CDD\|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483314.1\|WP_000525103.1\|733402_735286_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_LS483314.1\|WP_000562498.1\|750402_751374_+\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NZ_LS483314.1\|WP_111688560.1\|740024_741083_+\|histidinol-phosphate-transaminase	gnl\|CDD\|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NZ_LS483314.1\|WP_000429006.1\|742599_743517_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79

>NZ_LS483314.1|WP_000197275.1|741377_741920_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDVVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NZ_LS483314.1|WP_111688560.1|740024_741083_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPLHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVTALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NZ_LS483314.1|WP_000180991.1|738270_739785_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NZ_LS483314.1|WP_000589260.1|737300_738278_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NZ_LS483314.1|WP_000983677.1|735297_737079_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NZ_LS483314.1|WP_000525103.1|733402_735286_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKIIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQTVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NZ_LS483314.1|WP_000098285.1|731192_733133_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NZ_LS483314.1|WP_000022321.1|729714_730719_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRIGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NZ_LS483314.1|WP_042727613.1|729020_729731_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDLESLLKHYKIKLETFIELHSKAQYFVSIMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NZ_LS483314.1|WP_001790169.1|728726_728933_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NZ_LS483314.1|WP_000429006.1|742599_743517_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NZ_LS483314.1|WP_031797439.1|743606_743708_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYIEHIKLLFILIS
>NZ_LS483314.1|WP_000193751.1|743785_745291_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NZ_LS483314.1|WP_000930014.1|745631_746132_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NZ_LS483314.1|WP_001068497.1|746151_747018_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFIYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NZ_LS483314.1|WP_000692521.1|747818_748217_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NZ_LS483314.1|WP_111688562.1|748179_750285_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFNYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NZ_LS483314.1|WP_000562498.1|750402_751374_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NZ_LS483314.1|WP_000499195.1|751887_752043_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NZ_LS483314.1|WP_000876318.1|752081_753053_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

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Crispr_ID: NZ_LS483314_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_5

847607-847688

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_5

>merge|NZ_LS483314|5|847607-847688|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NZ_LS483314|5|5|847607-847688|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_001190695.1\|845087_845408_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_LS483314.1\|WP_000205579.1\|854654_855962_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NZ_LS483314.1\|WP_000569884.1\|842136_842631_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NZ_LS483314.1\|WP_001183858.1\|852615_853467_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NZ_LS483314.1\|WP_000422908.1\|844398_844938_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NZ_LS483314.1\|WP_000150013.1\|843599_844316_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NZ_LS483314.1\|WP_172449172.1\|840710_841292_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NZ_LS483314.1\|WP_000571218.1\|849281_850307_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NZ_LS483314.1\|WP_000255553.1\|841364_841982_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NZ_LS483314.1\|WP_000752917.1\|852187_852382_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_LS483314.1\|WP_000589549.1\|845551_845908_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NZ_LS483314.1\|WP_001018962.1\|848356_848743_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NZ_LS483314.1\|WP_000932212.1\|846624_847503_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NZ_LS483314.1\|WP_001065801.1\|848735_849032_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NZ_LS483314.1\|WP_000520233.1\|850299_850995_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NZ_LS483314.1\|WP_064131228.1\|853794_854556_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NZ_LS483314.1\|WP_000290490.1\|846065_846446_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NZ_LS483314.1\|WP_000974460.1\|843029_843452_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NZ_LS483314.1\|WP_001006453.1\|856067_857318_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NZ_LS483314.1\|WP_000732326.1\|851012_851834_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_001190695.1\|845087_845408_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.70086e-24
NZ_LS483314.1\|WP_000205579.1\|854654_855962_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	9.69519e-136
NZ_LS483314.1\|WP_000569884.1\|842136_842631_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NZ_LS483314.1\|WP_001183858.1\|852615_853467_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NZ_LS483314.1\|WP_000422908.1\|844398_844938_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NZ_LS483314.1\|WP_000150013.1\|843599_844316_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	5.95463e-148
NZ_LS483314.1\|WP_172449172.1\|840710_841292_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.64487e-48
NZ_LS483314.1\|WP_000571218.1\|849281_850307_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NZ_LS483314.1\|WP_000255553.1\|841364_841982_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.40612e-61
NZ_LS483314.1\|WP_000752917.1\|852187_852382_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NZ_LS483314.1\|WP_000589549.1\|845551_845908_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NZ_LS483314.1\|WP_001018962.1\|848356_848743_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NZ_LS483314.1\|WP_000932212.1\|846624_847503_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	1.72543e-74
NZ_LS483314.1\|WP_001065801.1\|848735_849032_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NZ_LS483314.1\|WP_000520233.1\|850299_850995_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NZ_LS483314.1\|WP_064131228.1\|853794_854556_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	6.17029e-150
NZ_LS483314.1\|WP_000290490.1\|846065_846446_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	1.28962e-69
NZ_LS483314.1\|WP_000974460.1\|843029_843452_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	5.58225e-61
NZ_LS483314.1\|WP_001006453.1\|856067_857318_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NZ_LS483314.1\|WP_000732326.1\|851012_851834_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112

>NZ_LS483314.1|WP_000932212.1|846624_847503_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQEHLKSLDADNEDIPFSGAFSIKFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NZ_LS483314.1|WP_000290490.1|846065_846446_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSKMIGE
>NZ_LS483314.1|WP_000589549.1|845551_845908_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NZ_LS483314.1|WP_001190695.1|845087_845408_-|thioredoxin-family-protein
MQSIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NZ_LS483314.1|WP_000422908.1|844398_844938_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NZ_LS483314.1|WP_000150013.1|843599_844316_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NZ_LS483314.1|WP_000974460.1|843029_843452_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NZ_LS483314.1|WP_000569884.1|842136_842631_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NZ_LS483314.1|WP_000255553.1|841364_841982_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIITAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLIF
>NZ_LS483314.1|WP_172449172.1|840710_841292_+|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYTSSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NZ_LS483314.1|WP_001018962.1|848356_848743_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NZ_LS483314.1|WP_001065801.1|848735_849032_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NZ_LS483314.1|WP_000571218.1|849281_850307_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NZ_LS483314.1|WP_000520233.1|850299_850995_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NZ_LS483314.1|WP_000732326.1|851012_851834_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NZ_LS483314.1|WP_000752917.1|852187_852382_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NZ_LS483314.1|WP_001183858.1|852615_853467_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NZ_LS483314.1|WP_064131228.1|853794_854556_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLIMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NZ_LS483314.1|WP_000205579.1|854654_855962_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NZ_LS483314.1|WP_001006453.1|856067_857318_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

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Crispr_ID: NZ_LS483314_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_6

1159871-1159956

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_6

>merge|NZ_LS483314|6|1159871-1159956|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGG

>NZ_LS483314|6|6|1159871-1159956|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACATAGAAGCTGGCGG
AAAGTCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_001032816.1\|1156154_1156340_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000857485.1\|1157671_1158631_-\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
NZ_LS483314.1\|WP_000739570.1\|1152667_1153069_-\|formyl-peptide-receptor-like-1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
NZ_LS483314.1\|WP_000432077.1\|1165066_1166623_+\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NZ_LS483314.1\|WP_000584398.1\|1153739_1154246_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000398672.1\|1169757_1169892_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_LS483314.1\|WP_000739523.1\|1161775_1162501_-\|superantigen-like-protein-SSL14	unknown	unknown	gnl\|CDD\|171855
NZ_LS483314.1\|WP_001063559.1\|1160955_1161681_-\|superantigen-like-protein-SSL13	unknown	unknown	gnl\|CDD\|106307
NZ_LS483314.1\|WP_000149429.1\|1166930_1167158_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000147103.1\|1169948_1170083_+\|beta-class-phenol-soluble-modulin	unknown	unknown	gnl\|CDD\|368464
NZ_LS483314.1\|WP_000793612.1\|1162938_1163940_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
NZ_LS483314.1\|WP_001239285.1\|1167462_1168410_-\|TDT-family-transporter	unknown	unknown	gnl\|CDD\|187765
NZ_LS483314.1\|WP_000791581.1\|1154504_1155002_+\|complement-convertase-inhibitor-Efb	unknown	unknown	gnl\|CDD\|289007
NZ_LS483314.1\|WP_000765708.1\|1159303_1159450_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001074342.1\|1163962_1164895_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
NZ_LS483314.1\|WP_000669528.1\|1155152_1155503_+\|complement-inhibitor-SCIN-family-protein	unknown	unknown	gnl\|CDD\|371594
NZ_LS483314.1\|WP_000739208.1\|1151968_1152298_+\|complement-convertase-inhibitor-Ecb	unknown	unknown	gnl\|CDD\|289007
NZ_LS483314.1\|WP_001245802.1\|1168658_1168847_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225382
NZ_LS483314.1\|WP_001802045.1\|1159406_1159631_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000231632.1\|1156961_1157195_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000857485.1\|1157671_1158631_-\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.4958e-141
NZ_LS483314.1\|WP_000739570.1\|1152667_1153069_-\|formyl-peptide-receptor-like-1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	5.2726e-76
NZ_LS483314.1\|WP_000432077.1\|1165066_1166623_+\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NZ_LS483314.1\|WP_000398672.1\|1169757_1169892_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	6.35158e-13
NZ_LS483314.1\|WP_001074342.1\|1163962_1164895_+\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
NZ_LS483314.1\|WP_001063559.1\|1160955_1161681_-\|superantigen-like-protein-SSL13	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	1.29834e-148
NZ_LS483314.1\|WP_001245802.1\|1168658_1168847_+\|hypothetical-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
NZ_LS483314.1\|WP_000147103.1\|1169948_1170083_+\|beta-class-phenol-soluble-modulin	gnl\|CDD\|368464	pfam05480, Staph_haemo, Staphylococcus haemolytic protein. This family consists of several different short Staphylococcal proteins, it contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.	4.87929e-13
NZ_LS483314.1\|WP_000793612.1\|1162938_1163940_+\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
NZ_LS483314.1\|WP_000739208.1\|1151968_1152298_+\|complement-convertase-inhibitor-Ecb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.51827e-21
NZ_LS483314.1\|WP_000739523.1\|1161775_1162501_-\|superantigen-like-protein-SSL14	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	8.18566e-161
NZ_LS483314.1\|WP_000669528.1\|1155152_1155503_+\|complement-inhibitor-SCIN-family-protein	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	8.46865e-41
NZ_LS483314.1\|WP_000791581.1\|1154504_1155002_+\|complement-convertase-inhibitor-Efb	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	2.84801e-27
NZ_LS483314.1\|WP_001239285.1\|1167462_1168410_-\|TDT-family-transporter	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.44089e-84

>NZ_LS483314.1|WP_001802045.1|1159406_1159631_+|hypothetical-protein
MLIQERGLKMTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>NZ_LS483314.1|WP_000765708.1|1159303_1159450_+|hypothetical-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>NZ_LS483314.1|WP_000857485.1|1157671_1158631_-|alpha-hemolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>NZ_LS483314.1|WP_000231632.1|1156961_1157195_-|hypothetical-protein
MVFNDWEINVVYSGEHEVVTNEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIQNPNVDEH
>NZ_LS483314.1|WP_001032816.1|1156154_1156340_-|hypothetical-protein
MNKHINKKASKLLEDYKKVQQRKSEETDKGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>NZ_LS483314.1|WP_000669528.1|1155152_1155503_+|complement-inhibitor-SCIN-family-protein
MKFKKYILTGTLALLLSSTAIATIEGNKADASSKKDYIIQSEFHDKRIAEELKSLLDQSYVNDLAAGSLNPYYKRTIMMNQYRAKAALKSNNFAKMAEAKVALENIYKEIDEIINR
>NZ_LS483314.1|WP_000791581.1|1154504_1155002_+|complement-convertase-inhibitor-Efb
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVR
>NZ_LS483314.1|WP_000584398.1|1153739_1154246_+|hypothetical-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>NZ_LS483314.1|WP_000739570.1|1152667_1153069_-|formyl-peptide-receptor-like-1-inhibitory-protein
MKKNITKTIIASTVIAAGLSTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSIYWD
>NZ_LS483314.1|WP_000739208.1|1151968_1152298_+|complement-convertase-inhibitor-Ecb
MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNAETVKKYNEYQTNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLVLKYNTLK
>NZ_LS483314.1|WP_001063559.1|1160955_1161681_-|superantigen-like-protein-SSL13
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDQETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>NZ_LS483314.1|WP_000739523.1|1161775_1162501_-|superantigen-like-protein-SSL14
MKKNIMNKLVLSTALLLLETTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPRNAEIEVILEKSN
>NZ_LS483314.1|WP_000793612.1|1162938_1163940_+|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDNIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>NZ_LS483314.1|WP_001074342.1|1163962_1164895_+|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>NZ_LS483314.1|WP_000432077.1|1165066_1166623_+|YfcC-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKNDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGVLITQVLIYS
>NZ_LS483314.1|WP_000149429.1|1166930_1167158_+|hypothetical-protein
MTHLTKVLVTLTGICVVLLFSKYFVAYANMVFDWNLRWYMLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>NZ_LS483314.1|WP_001239285.1|1167462_1168410_-|TDT-family-transporter
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
>NZ_LS483314.1|WP_001245802.1|1168658_1168847_+|hypothetical-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>NZ_LS483314.1|WP_000398672.1|1169757_1169892_+|beta-class-phenol-soluble-modulin
MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
>NZ_LS483314.1|WP_000147103.1|1169948_1170083_+|beta-class-phenol-soluble-modulin
MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF

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Crispr_ID: NZ_LS483314_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_7

1768045-1768131

Orphan

Consensus_repeat	Method
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_7

>merge|NZ_LS483314|7|1768045-1768131|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGACCATGCAAGTTGGGGTGGGCCCCAACATAGAA

>NZ_LS483314|7|7|1768045-1768131|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGACC
ATGCAAGTTGGGGTGGGCCCCAACATAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_000840584.1\|1775972_1776920_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NZ_LS483314.1\|WP_000634175.1\|1773936_1774437_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_LS483314.1\|WP_000136253.1\|1777042_1777537_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_LS483314.1\|WP_000829167.1\|1751764_1752886_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NZ_LS483314.1\|WP_001789984.1\|1772455_1772554_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_000883648.1\|1759935_1760880_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NZ_LS483314.1\|WP_001836688.1\|1763610_1766808_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NZ_LS483314.1\|WP_000471571.1\|1760879_1761737_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NZ_LS483314.1\|WP_000626076.1\|1766828_1767770_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NZ_LS483314.1\|WP_000689998.1\|1772677_1773796_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NZ_LS483314.1\|WP_000777190.1\|1770442_1771132_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NZ_LS483314.1\|WP_000818525.1\|1753233_1754595_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NZ_LS483314.1\|WP_000160435.1\|1768221_1769520_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_LS483314.1\|WP_000040063.1\|1774682_1775885_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_LS483314.1\|WP_000058389.1\|1761931_1763161_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NZ_LS483314.1\|WP_000717561.1\|1758698_1759667_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483314.1\|WP_001232648.1\|1756919_1758677_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NZ_LS483314.1\|WP_000277602.1\|1769724_1770138_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NZ_LS483314.1\|WP_000123164.1\|1750447_1751716_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NZ_LS483314.1\|WP_000161674.1\|1771306_1772362_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_000840584.1\|1775972_1776920_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	1.04193e-56
NZ_LS483314.1\|WP_000634175.1\|1773936_1774437_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NZ_LS483314.1\|WP_000136253.1\|1777042_1777537_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NZ_LS483314.1\|WP_000829167.1\|1751764_1752886_-\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NZ_LS483314.1\|WP_000883648.1\|1759935_1760880_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NZ_LS483314.1\|WP_001836688.1\|1763610_1766808_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NZ_LS483314.1\|WP_000471571.1\|1760879_1761737_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NZ_LS483314.1\|WP_000626076.1\|1766828_1767770_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	2.09048e-98
NZ_LS483314.1\|WP_000689998.1\|1772677_1773796_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NZ_LS483314.1\|WP_000777190.1\|1770442_1771132_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	1.10209e-133
NZ_LS483314.1\|WP_000818525.1\|1753233_1754595_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NZ_LS483314.1\|WP_000160435.1\|1768221_1769520_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_LS483314.1\|WP_000040063.1\|1774682_1775885_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_LS483314.1\|WP_000058389.1\|1761931_1763161_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NZ_LS483314.1\|WP_000717561.1\|1758698_1759667_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483314.1\|WP_001232648.1\|1756919_1758677_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NZ_LS483314.1\|WP_000277602.1\|1769724_1770138_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19
NZ_LS483314.1\|WP_000123164.1\|1750447_1751716_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NZ_LS483314.1\|WP_000161674.1\|1771306_1772362_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	9.25455e-126

>NZ_LS483314.1|WP_000626076.1|1766828_1767770_-|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NZ_LS483314.1|WP_001836688.1|1763610_1766808_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQDVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEVNQLDINQEYLTQVDVIAQKCNAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKKTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQKGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVMLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NZ_LS483314.1|WP_000058389.1|1761931_1763161_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NZ_LS483314.1|WP_000471571.1|1760879_1761737_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEILKIHQEVTK
>NZ_LS483314.1|WP_000883648.1|1759935_1760880_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDVEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NZ_LS483314.1|WP_000717561.1|1758698_1759667_-|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NZ_LS483314.1|WP_001232648.1|1756919_1758677_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NZ_LS483314.1|WP_000818525.1|1753233_1754595_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NZ_LS483314.1|WP_000829167.1|1751764_1752886_-|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NZ_LS483314.1|WP_000123164.1|1750447_1751716_-|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
>NZ_LS483314.1|WP_000160435.1|1768221_1769520_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NZ_LS483314.1|WP_000277602.1|1769724_1770138_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NZ_LS483314.1|WP_000777190.1|1770442_1771132_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKVNFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NZ_LS483314.1|WP_000161674.1|1771306_1772362_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLTSGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIILEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
>NZ_LS483314.1|WP_001789984.1|1772455_1772554_-|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NZ_LS483314.1|WP_000689998.1|1772677_1773796_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NZ_LS483314.1|WP_000634175.1|1773936_1774437_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NZ_LS483314.1|WP_000040063.1|1774682_1775885_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NZ_LS483314.1|WP_000840584.1|1775972_1776920_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEIDIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINVLKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK
>NZ_LS483314.1|WP_000136253.1|1777042_1777537_-|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI

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Crispr_ID: NZ_LS483314_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483314_8

2617661-2617742

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483314_8

>merge|NZ_LS483314|8|2617661-2617742|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGATGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGG

>NZ_LS483314|8|8|2617661-2617742|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGG	ATGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483314.1\|WP_001163740.1\|2625181_2626288_-\|NAD(P)-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|379355
NZ_LS483314.1\|WP_000447709.1\|2626582_2626879_-\|DUF4176-domain-containing-protein	unknown	unknown	gnl\|CDD\|226892
NZ_LS483314.1\|WP_042727680.1\|2621883_2622714_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NZ_LS483314.1\|WP_001791985.1\|2615442_2615571_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_001795157.1\|2616492_2616993_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483314.1\|WP_111688692.1\|2612951_2613653_-\|lytic-transglycosylase-IsaA	unknown	unknown	gnl\|CDD\|381607
NZ_LS483314.1\|WP_000616225.1\|2617846_2618224_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|226134
NZ_LS483314.1\|WP_000895193.1\|2623847_2625188_-\|ferrous-iron-transporter-B	unknown	unknown	gnl\|CDD\|223447
NZ_LS483314.1\|WP_000379821.1\|2609864_2611676_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NZ_LS483314.1\|WP_000651837.1\|2618240_2619062_-\|NmrA/HSCARG-family-protein	unknown	unknown	gnl\|CDD\|187561
NZ_LS483314.1\|WP_000161829.1\|2620062_2620767_+\|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|187585
NZ_LS483314.1\|WP_000706519.1\|2622860_2623751_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NZ_LS483314.1\|WP_000996736.1\|2612187_2612676_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NZ_LS483314.1\|WP_000200684.1\|2614260_2615316_-\|PTS-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226167
NZ_LS483314.1\|WP_001795496.1\|2608073_2608562_-\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NZ_LS483314.1\|WP_000836425.1\|2620853_2621864_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|225070
NZ_LS483314.1\|WP_001789900.1\|2615725_2616295_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_LS483314.1\|WP_000697134.1\|2617212_2617443_+\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|226677
NZ_LS483314.1\|WP_001224182.1\|2619512_2620070_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_LS483314.1\|WP_000725233.1\|2608736_2609504_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451

Protein	Function_ID	Function_description	E-value
NZ_LS483314.1\|WP_001163740.1\|2625181_2626288_-\|NAD(P)-binding-domain-containing-protein	gnl\|CDD\|379355	pfam13738, Pyr_redox_3, Pyridine nucleotide-disulphide oxidoreductase.	4.45347e-126
NZ_LS483314.1\|WP_000447709.1\|2626582_2626879_-\|DUF4176-domain-containing-protein	gnl\|CDD\|226892	COG4495, COG4495, Uncharacterized protein conserved in bacteria [Function unknown].	5.38415e-36
NZ_LS483314.1\|WP_042727680.1\|2621883_2622714_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.54673e-18
NZ_LS483314.1\|WP_000895193.1\|2623847_2625188_-\|ferrous-iron-transporter-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	1.90855e-93
NZ_LS483314.1\|WP_111688692.1\|2612951_2613653_-\|lytic-transglycosylase-IsaA	gnl\|CDD\|381607	cd13925, RPF, core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.	3.19038e-06
NZ_LS483314.1\|WP_000616225.1\|2617846_2618224_-\|VOC-family-protein	gnl\|CDD\|226134	COG3607, COG3607, Predicted lactoylglutathione lyase [General function prediction only].	1.45544e-58
NZ_LS483314.1\|WP_000379821.1\|2609864_2611676_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84
NZ_LS483314.1\|WP_000651837.1\|2618240_2619062_-\|NmrA/HSCARG-family-protein	gnl\|CDD\|187561	cd05251, NmrA_like_SDR_a, NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs. NmrA and HSCARG like proteins. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.56436e-84
NZ_LS483314.1\|WP_000161829.1\|2620062_2620767_+\|SDR-family-NAD(P)-dependent-oxidoreductase	gnl\|CDD\|187585	cd05324, carb_red_PTCR-like_SDR_c, Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs. PTCR is a classical SDR which catalyzes the NADPH-dependent reduction of ketones on steroids and prostaglandins. Unlike most SDRs, PTCR functions as a monomer. This subgroup also includes human carbonyl reductase 1 (CBR1) and CBR3. CBR1 is an NADPH-dependent SDR with broad substrate specificity and may be responsible for the in vivo reduction of quinones, prostaglandins, and other carbonyl-containing compounds. In addition it includes poppy NADPH-dependent salutaridine reductase which catalyzes the stereospecific reduction of salutaridine to 7(S)-salutaridinol in the biosynthesis of morphine, and Arabidopsis SDR1,a menthone reductase, which catalyzes the reduction of menthone to neomenthol, a compound with antimicrobial activity; SDR1 can also carry out neomenthol oxidation. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	4.08524e-67
NZ_LS483314.1\|WP_000706519.1\|2622860_2623751_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.17569e-76
NZ_LS483314.1\|WP_000996736.1\|2612187_2612676_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.6785e-11
NZ_LS483314.1\|WP_000200684.1\|2614260_2615316_-\|PTS-transporter-subunit-IIC	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	5.38046e-117
NZ_LS483314.1\|WP_000836425.1\|2620853_2621864_+\|amidohydrolase	gnl\|CDD\|225070	COG2159, COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	7.39377e-78
NZ_LS483314.1\|WP_001789900.1\|2615725_2616295_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.43347e-07
NZ_LS483314.1\|WP_000697134.1\|2617212_2617443_+\|DUF896-domain-containing-protein	gnl\|CDD\|226677	COG4224, COG4224, Uncharacterized protein conserved in bacteria [Function unknown].	6.01061e-31
NZ_LS483314.1\|WP_001224182.1\|2619512_2620070_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.50396e-13
NZ_LS483314.1\|WP_000725233.1\|2608736_2609504_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.0489e-31

>NZ_LS483314.1|WP_000697134.1|2617212_2617443_+|DUF896-domain-containing-protein
MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLTTFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN
>NZ_LS483314.1|WP_001795157.1|2616492_2616993_+|hypothetical-protein
MTSIFVFAYLNNTSGNMLFRQQMICACLLANVRHSSIVCLNNICCIVDMRCLNTKIGGIDVSETDEPQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHIIIARGKKRIDYRLSYNFYTTYYDNVEIKKIDCEYTYAMPIAILIRHTMSFDNAHFFAQLRHPVL
>NZ_LS483314.1|WP_001789900.1|2615725_2616295_+|TetR/AcrR-family-transcriptional-regulator
MMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKDITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIASYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAAGISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF
>NZ_LS483314.1|WP_001791985.1|2615442_2615571_-|hypothetical-protein
MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR
>NZ_LS483314.1|WP_000200684.1|2614260_2615316_-|PTS-transporter-subunit-IIC
MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDYHPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAWMITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKMITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIGISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSALVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADIIYRKVFRLYTNDIFKFMG
>NZ_LS483314.1|WP_111688692.1|2612951_2613653_-|lytic-transglycosylase-IsaA
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRIGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>NZ_LS483314.1|WP_000996736.1|2612187_2612676_-|GNAT-family-N-acetyltransferase
MAINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIEHNYLNNGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDKGYRNLKIGKKLLDKVIMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNLKD
>NZ_LS483314.1|WP_000379821.1|2609864_2611676_-|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
>NZ_LS483314.1|WP_000725233.1|2608736_2609504_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAVEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NZ_LS483314.1|WP_001795496.1|2608073_2608562_-|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NZ_LS483314.1|WP_000616225.1|2617846_2618224_-|VOC-family-protein
MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIGQTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGAVVQEPTVSQGFYGAMFKDLDGHHFNFLVC
>NZ_LS483314.1|WP_000651837.1|2618240_2619062_-|NmrA/HSCARG-family-protein
MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIGHPHLSIVEGDLSDNVSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQHIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDERITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSEVTGKSTVIEGEFVSGVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQNYNK
>NZ_LS483314.1|WP_001224182.1|2619512_2620070_+|TetR/AcrR-family-transcriptional-regulator
MRKDAIENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
>NZ_LS483314.1|WP_000161829.1|2620062_2620767_+|SDR-family-NAD(P)-dependent-oxidoreductase
MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQKLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSSKSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIGADGPTGTFINGDGEMPW
>NZ_LS483314.1|WP_000836425.1|2620853_2621864_+|amidohydrolase
MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTGFTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIAQYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKTAENLGVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSGIFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKPQFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSSNN
>NZ_LS483314.1|WP_042727680.1|2621883_2622714_+|alpha/beta-hydrolase
METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKDHFTVVAVDRRDYGESELTEPIPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGSSSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDYIVHQILTEGLEKGMKTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSKFEIRQYTHSDITLDDFTKYSDKITLLNGTDSRGSFPQDVNFYINKETGIPIVDIPGGHLGYIQKPEGFADVLLNLWG
>NZ_LS483314.1|WP_000706519.1|2622860_2623751_-|GTP-binding-protein
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHKSLHQMINHQFVQSPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>NZ_LS483314.1|WP_000895193.1|2623847_2625188_-|ferrous-iron-transporter-B
MLEVKYDMRTGHYTPIPNEPHYLVISHADKLTATEKAKLRLLIIKQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPIGIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVVILISLSTAIIDQTGLKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQCHTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLKKNDQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPILNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLVFFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMVTSLSLVIGVGIIVKIVMLII
>NZ_LS483314.1|WP_001163740.1|2625181_2626288_-|NAD(P)-binding-domain-containing-protein
MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKHWPKSTLTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYELNIFENTVVTNISVDDAFYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDFDNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQRLGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVHTPHEPILATGFDATKNPIVQQLFVTTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLTQREGLPAKQEVIENYQKNQMYLDDYSCCEVSCTC
>NZ_LS483314.1|WP_000447709.1|2626582_2626879_-|DUF4176-domain-containing-protein
METIGSIIYLKEGSQKLMIINRGPIVEIENQKYMFDYSACKYPIGVVEDEIYYFNEENIDSVIFKGYSDQDEVRFQELFENMKQNLDSEIQRGEVTPQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483314_1	1.1\|142214\|34\|NZ_LS483314\|CRISPRCasFinder	142214-142247	34	NZ_LS483314.1	1464733-1464766	0	1.0
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	1245491-1245516	0	1.0
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	2732190-2732215	0	1.0
NZ_LS483314_8	8.1\|2617685\|34\|NZ_LS483314\|CRISPRCasFinder	2617685-2617718	34	NZ_LS483314.1	1464733-1464766	0	1.0
NZ_LS483314_1	1.1\|142214\|34\|NZ_LS483314\|CRISPRCasFinder	142214-142247	34	NZ_LS483314.1	1245379-1245412	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	847990-848024	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	848046-848080	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	1245458-1245492	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	2295430-2295464	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	2459942-2459976	1	0.971
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	2732214-2732248	1	0.971
NZ_LS483314_5	5.1\|847631\|34\|NZ_LS483314\|CRISPRCasFinder	847631-847664	34	NZ_LS483314.1	1464733-1464766	1	0.971
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	751596-751621	1	0.962
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	847966-847991	1	0.962
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	848022-848047	1	0.962
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	848078-848103	1	0.962
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	2732246-2732271	1	0.962
NZ_LS483314_8	8.1\|2617685\|34\|NZ_LS483314\|CRISPRCasFinder	2617685-2617718	34	NZ_LS483314.1	1245379-1245412	1	0.971
NZ_LS483314_1	1.1\|142214\|34\|NZ_LS483314\|CRISPRCasFinder	142214-142247	34	NZ_LS483314.1	1377233-1377266	2	0.941
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	751619-751653	2	0.943
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	1155900-1155934	2	0.943
NZ_LS483314_2	2.1\|265492\|35\|NZ_LS483314\|CRISPRCasFinder	265492-265526	35	NZ_LS483314.1	1159868-1159902	2	0.943
NZ_LS483314_5	5.1\|847631\|34\|NZ_LS483314\|CRISPRCasFinder	847631-847664	34	NZ_LS483314.1	1245379-1245412	2	0.941
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	751540-751565	2	0.923
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	751652-751677	2	0.923
NZ_LS483314_6	6.1\|1159901\|26\|NZ_LS483314\|CRISPRCasFinder	1159901-1159926	26	NZ_LS483314.1	2459974-2459999	2	0.923
NZ_LS483314_8	8.1\|2617685\|34\|NZ_LS483314\|CRISPRCasFinder	2617685-2617718	34	NZ_LS483314.1	1377233-1377266	2	0.941

1. spacer 1.1|142214|34|NZ_LS483314|CRISPRCasFinder matches to position: 1464733-1464766, mismatch: 0, identity: 1.0

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
**********************************

2. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 1245491-1245516, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

3. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 2732190-2732215, mismatch: 0, identity: 1.0

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagctggcgg	Protospacer
**************************

4. spacer 8.1|2617685|34|NZ_LS483314|CRISPRCasFinder matches to position: 1464733-1464766, mismatch: 0, identity: 1.0

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaaattggattcccaat	Protospacer
**********************************

5. spacer 1.1|142214|34|NZ_LS483314|CRISPRCasFinder matches to position: 1245379-1245412, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaagttggattcccaat	Protospacer
********************.*************

6. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 847990-848024, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

7. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 848046-848080, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

8. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 1245458-1245492, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

9. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 2295430-2295464, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcatacaataatgtgcaagttggcg	Protospacer
**.********************************

10. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 2459942-2459976, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcttacaataatgtgcaagttggcg	Protospacer
************ **********************

11. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 2732214-2732248, mismatch: 1, identity: 0.971

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagcctacaataatgtgcaagttggcg	Protospacer
************ **********************

12. spacer 5.1|847631|34|NZ_LS483314|CRISPRCasFinder matches to position: 1464733-1464766, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

13. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 751596-751621, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacatagaagcaggcgg	Protospacer
******************** *****

14. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 847966-847991, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

15. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 848022-848047, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

16. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 848078-848103, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagctggcgg	Protospacer
*************.************

17. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 2732246-2732271, mismatch: 1, identity: 0.962

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacaaagaagctggcgg	Protospacer
************* ************

18. spacer 8.1|2617685|34|NZ_LS483314|CRISPRCasFinder matches to position: 1245379-1245412, mismatch: 1, identity: 0.971

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atgggccccaacaaagagaagttggattcccaat	Protospacer
********************.*************

19. spacer 1.1|142214|34|NZ_LS483314|CRISPRCasFinder matches to position: 1377233-1377266, mismatch: 2, identity: 0.941

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atggagcccaacaaagagaaattggattcccaat	Protospacer
****. ****************************

20. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 751619-751653, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cggaaagtcagctaacaataatgtgcaagttggcg	Protospacer
************  *********************

21. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 1155900-1155934, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcatacaaaaatgtgcaagttggcg	Protospacer
**.*************** ****************

22. spacer 2.1|265492|35|NZ_LS483314|CRISPRCasFinder matches to position: 1159868-1159902, mismatch: 2, identity: 0.943

cggaaagtcagcatacaataatgtgcaagttggcg	CRISPR spacer
cgaaaagtcagcttacaataatgtgcaagttggcg	Protospacer
**.********* **********************

23. spacer 5.1|847631|34|NZ_LS483314|CRISPRCasFinder matches to position: 1245379-1245412, mismatch: 2, identity: 0.941

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaacttctctttgttggggcccat	Protospacer
****.********.********************

24. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 751540-751565, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagaagcaggcgg	Protospacer
*************.****** *****

25. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 751652-751677, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacataaaagcaggcgg	Protospacer
***************.**** *****

26. spacer 6.1|1159901|26|NZ_LS483314|CRISPRCasFinder matches to position: 2459974-2459999, mismatch: 2, identity: 0.923

cggggccccaacatagaagctggcgg	CRISPR spacer
cggggccccaacacagtagctggcgg	Protospacer
*************.** *********

27. spacer 8.1|2617685|34|NZ_LS483314|CRISPRCasFinder matches to position: 1377233-1377266, mismatch: 2, identity: 0.941

atgggccccaacaaagagaaattggattcccaat	CRISPR spacer
atggagcccaacaaagagaaattggattcccaat	Protospacer
****. ****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483314_7	7.1\|1768075\|27\|NZ_LS483314\|CRISPRCasFinder	1768075-1768101	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815

1. spacer 7.1|1768075|27|NZ_LS483314|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

gaatttcgaaaagaaattctacagacc	CRISPR spacer
ctatttccaaaagaaattatacagatc	Protospacer
  ***** ********** ******.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

720233 : 728053

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|720233_721289_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|721288_721975_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|721949_722423_-	DoxX family protein	NA	NA	NA	NA
WP_001093556.1\|722764_723205_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000637687.1\|723484_724069_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|724167_724881_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|724884_725304_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|725305_725974_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|726324_726918_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217794.1\|726901_728053_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	3.5e-23	36.1

DBSCAN-SWA_2

740024 : 754754

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111688560.1\|740024_741083_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	3.9e-21	27.7
WP_000197275.1\|741377_741920_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429006.1\|742599_743517_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031797439.1\|743606_743708_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|743785_745291_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|745631_746132_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|746151_747018_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|747818_748217_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_111688562.1\|748179_750285_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
WP_000562498.1\|750402_751374_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|751887_752043_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|752081_753053_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1\|753039_753996_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616842.1\|753992_754754_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	8.5e-18	31.6

DBSCAN-SWA_3

805303 : 821807

Staphylococcus_phage(64.71%)

terminase,integrase,coat

attL 802187:802202|attR 824011:824026

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
802187:802202	attL	NA	NA	NA	NA
WP_001050063.1\|805303_807676_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.1e-93	39.0
WP_001085185.1\|807697_808162_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
WP_111688701.1\|808724_809834_-\|integrase	site-specific integrase	H0UST3	Bacillus_phage	2.0e-76	44.6
WP_000272128.1\|809823_810753_-	helix-turn-helix transcriptional regulator	Q9AZH9	Lactococcus_phage	2.2e-12	35.6
WP_000163542.1\|810940_811159_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000800860.1\|811171_811309_+	hypothetical protein	NA	NA	NA	NA
WP_000850930.1\|811310_811721_+	hypothetical protein	A0A2H4JBF1	uncultured_Caudovirales_phage	2.4e-59	85.8
WP_001103953.1\|811721_812015_+	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	8.9e-24	61.8
WP_001574576.1\|812102_812972_+	primase C-terminal domain-containing protein	A0A1W6JQL5	Staphylococcus_phage	2.7e-161	96.2
WP_001574574.1\|812988_814446_+	hypothetical protein	A0A1W6JQD6	Staphylococcus_phage	1.0e-277	96.3
WP_001039168.1\|814746_815109_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
WP_000998182.1\|815110_815395_+	hypothetical protein	A0A1W6JQE4	Staphylococcus_phage	1.0e-45	92.6
WP_001019780.1\|815391_816033_+	hypothetical protein	Q4ZE67	Staphylococcus_phage	5.9e-113	94.4
WP_001190615.1\|816549_816891_+	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_111688564.1\|816902_817481_+	pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.4e-28	38.4
WP_000853281.1\|817498_817717_+	hypothetical protein	NA	NA	NA	NA
WP_111688566.1\|817767_818295_+\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	4.3e-85	94.9
WP_065252035.1\|818297_818639_+	pathogenicity island protein	A0A1W6JQM3	Staphylococcus_phage	1.9e-57	98.2
WP_111688568.1\|818635_819205_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	8.7e-100	96.8
WP_000624990.1\|819633_820152_+	hypothetical protein	NA	NA	NA	NA
WP_000591858.1\|820148_820577_+	hypothetical protein	NA	NA	NA	NA
WP_000705255.1\|820563_821343_+	hypothetical protein	NA	NA	NA	NA
WP_078161771.1\|821522_821807_+	DUF3102 domain-containing protein	A0A2H4JAH5	uncultured_Caudovirales_phage	4.3e-23	57.6
824011:824026	attR	NA	NA	NA	NA

DBSCAN-SWA_4

856067 : 902372

Staphylococcus_phage(54.69%)

tail,holin,terminase,integrase,portal,plate,head

attL 852211:852226|attR 878374:878389

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
852211:852226	attL	NA	NA	NA	NA
WP_001006453.1\|856067_857318_+	cysteine desulfurase	Q2XUY6	environmental_halophage	1.1e-110	44.8
WP_001010508.1\|857307_857772_+	SUF system NifU family Fe-S cluster assembly protein	NA	NA	NA	NA
WP_111688574.1\|857922_859320_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_111688576.1\|859387_860437_-\|integrase	site-specific integrase	A1KWY3	Staphylococcus_virus	1.3e-202	99.7
WP_000337827.1\|860549_860729_+	hypothetical protein	Q4ZBP0	Staphylococcus_phage	3.7e-25	100.0
WP_111688578.1\|860708_861641_-	hypothetical protein	A0EX19	Staphylococcus_virus	2.5e-173	99.7
WP_111688580.1\|861676_862288_-	helix-turn-helix domain-containing protein	B5WZL2	Staphylococcus_phage	5.5e-100	89.2
WP_074371007.1\|862458_862686_+	BetR domain protein	B5WZL3	Staphylococcus_phage	2.6e-31	93.3
WP_015978377.1\|862746_862908_+	hypothetical protein	Q4ZB04	Staphylococcus_virus	4.3e-20	100.0
WP_111688703.1\|862900_863194_-	hypothetical protein	Q4ZB03	Staphylococcus_virus	9.8e-39	96.3
WP_111688582.1\|863201_863939_+	ORF6C domain-containing protein	M9NS32	Staphylococcus_phage	4.7e-130	98.3
WP_031864595.1\|864043_864247_-	hypothetical protein	A0A2H4JBA9	uncultured_Caudovirales_phage	1.7e-18	69.8
WP_042856228.1\|864529_864691_+	DUF1270 family protein	C7F7L3	Staphylococcus_phage	7.2e-20	98.1
WP_048667633.1\|864783_865044_+	DUF1108 family protein	Q4ZBM7	Staphylococcus_phage	4.4e-43	97.7
WP_000002516.1\|865058_865538_+	siphovirus Gp157 family protein	A0A0H4J328	Staphylococcus_phage	1.1e-82	100.0
WP_106910141.1\|865537_866176_+	ERF family protein	A0A059T7J7	Staphylococcus_phage	1.1e-114	98.6
WP_070008590.1\|866175_866601_+	single-stranded DNA-binding protein	A0A0E3XC62	Staphylococcus_phage	3.0e-65	90.8
WP_001004506.1\|866611_867163_+	HNH endonuclease	A0A2H4PQR4	Staphylococcus_phage	1.6e-106	100.0
WP_111688584.1\|867163_867838_+	hypothetical protein	C8CGZ0	Staphylococcus_phage	2.6e-127	98.7
WP_111688586.1\|867830_868586_+	DnaD domain protein	C8CGZ1	Staphylococcus_phage	1.1e-142	99.6
WP_001132247.1\|868585_868942_+	hypothetical protein	B7T0A8	Staphylococcus_virus	2.2e-61	97.5
WP_001106169.1\|868938_870180_+	AAA family ATPase	C8CGZ3	Staphylococcus_phage	3.3e-229	99.8
WP_001024406.1\|870176_870392_+	hypothetical protein	A9CR72	Staphylococcus_phage	2.8e-35	100.0
WP_001123688.1\|870394_870616_+	DUF3269 family protein	Q9G021	Staphylococcus_phage	1.3e-35	100.0
WP_000049798.1\|870626_871031_+	DUF1064 domain-containing protein	G4KNP2	Staphylococcus_phage	1.6e-68	100.0
WP_042903520.1\|871035_871221_+	DUF3113 family protein	A0A0N9BBI1	Staphylococcus_phage	5.4e-27	98.4
WP_016028254.1\|871221_871590_+	hypothetical protein	A0A2H4PQJ6	Staphylococcus_phage	3.1e-50	100.0
WP_111688588.1\|871593_871836_+	hypothetical protein	Q4ZDP7	Staphylococcus_virus	5.6e-40	96.2
WP_111688590.1\|871850_872099_+	DUF1024 family protein	Q4ZDW9	Staphylococcus_virus	1.7e-36	97.6
WP_000185698.1\|872091_872631_+	dUTP diphosphatase	B2ZYX2	Staphylococcus_phage	3.7e-60	70.6
WP_000195800.1\|872667_872874_+	DUF1381 domain-containing protein	A0A2I6PEM9	Staphylococcus_phage	1.6e-16	95.6
WP_000592226.1\|872870_873257_+	hypothetical protein	Q4ZDW6	Staphylococcus_virus	4.0e-64	100.0
WP_000595275.1\|873253_873427_+	transcriptional activator RinB	Q4ZAX6	Staphylococcus_virus	3.5e-20	93.0
WP_000286968.1\|873427_873829_+	hypothetical protein	A0A2H4PQK5	Staphylococcus_phage	5.6e-69	100.0
WP_000594082.1\|874183_874678_+\|terminase	terminase	R4IH30	Staphylococcus_phage	1.1e-74	100.0
WP_001606760.1\|874670_875879_+\|terminase	PBSX family phage terminase large subunit	R4IG95	Staphylococcus_phage	6.1e-236	100.0
WP_172449173.1\|875892_877311_+\|portal	phage portal protein	Q4ZB45	Staphylococcus_virus	1.4e-271	98.7
WP_015978359.1\|877249_878230_+\|head	phage head morphogenesis protein	Q4ZB44	Staphylococcus_virus	1.2e-181	100.0
WP_000366930.1\|878327_878852_+	phage scaffolding protein	Q4ZB42	Staphylococcus_virus	2.9e-65	100.0
878374:878389	attR	NA	NA	NA	NA
WP_001044072.1\|878863_879823_+	hypothetical protein	Q4ZB40	Staphylococcus_virus	1.9e-179	100.0
WP_000278937.1\|879839_880166_+	Rho termination factor N-terminal domain-containing protein	Q4ZB39	Staphylococcus_virus	5.9e-53	100.0
WP_015978368.1\|880165_880480_+\|head,tail	phage head-tail connector protein	Q4ZB38	Staphylococcus_virus	2.6e-53	100.0
WP_015978367.1\|880472_880808_+\|head	phage head closure protein	Q4ZB37	Staphylococcus_virus	3.9e-60	100.0
WP_015978370.1\|880794_881208_+	HK97 gp10 family phage protein	Q4ZB36	Staphylococcus_virus	1.5e-77	100.0
WP_000270196.1\|881220_881658_+	DUF3168 domain-containing protein	A0A0E3T9M9	Staphylococcus_phage	2.1e-77	100.0
WP_000046067.1\|881644_882205_+	hypothetical protein	A0A0H4ITY2	Staphylococcus_phage	5.9e-101	100.0
WP_015978362.1\|882266_882761_+	hypothetical protein	Q4ZB32	Staphylococcus_virus	2.5e-87	100.0
WP_049948777.1\|882781_883123_+	hypothetical protein	W5R8J4	Staphylococcus_phage	4.6e-56	99.1
WP_031910547.1\|883125_886269_+\|terminase	terminase	A7YGV9	Staphylococcus_virus	1.7e-306	97.1
WP_000560198.1\|886283_887219_+\|tail	phage tail family protein	A7YGW1	Staphylococcus_virus	3.7e-180	100.0
WP_111688594.1\|887229_889116_+\|tail	phage tail protein	Q4ZAG4	Staphylococcus_virus	0.0e+00	99.8
WP_111688596.1\|889128_891027_+	hypothetical protein	Q4ZBX7	Staphylococcus_virus	0.0e+00	98.4
WP_111688598.1\|891026_892850_+\|plate	BppU family phage baseplate upper protein	A7YGW7	Staphylococcus_virus	0.0e+00	99.8
WP_000705888.1\|892849_893227_+	DUF2977 domain-containing protein	Q4ZAU9	Staphylococcus_virus	9.0e-61	100.0
WP_001800921.1\|893236_893410_+	XkdX family protein	A0A059T7K6	Staphylococcus_phage	1.3e-27	100.0
WP_000466784.1\|893450_893750_+	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
WP_000524040.1\|893886_895761_+	glucosaminidase domain-containing protein	Q4ZBX1	Staphylococcus_virus	0.0e+00	100.0
WP_111688600.1\|895773_896946_+\|plate	BppU family phage baseplate upper protein	I1W629	Staphylococcus_phage	2.7e-196	98.7
WP_111688602.1\|896951_897347_+	hypothetical protein	A0EWU9	Staphylococcus_virus	1.8e-67	98.5
WP_000611512.1\|897403_897658_+\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_000861038.1\|897669_898425_+	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000920041.1\|898615_899107_+	staphylokinase	A7TWR8	Staphylococcus_phage	8.0e-86	100.0
WP_001788502.1\|899495_899648_+	hypothetical protein	A0A0F6N3H2	Staphylococcus_phage	3.1e-20	100.0
WP_000139423.1\|899718_899829_+	hypothetical protein	W5R8J7	Staphylococcus_phage	1.7e-12	100.0
WP_001286805.1\|899830_900016_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.7e-26	100.0
WP_000990948.1\|901509_901692_+	hypothetical protein	NA	NA	NA	NA
WP_000180531.1\|901688_902372_+	hypothetical protein	A0A0A7S0U2	Clostridium_phage	1.1e-13	28.3

DBSCAN-SWA_5

985496 : 1039031

Streptococcus_phage(33.33%)

transposase,tRNA,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000448943.1\|985496_986486_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_111688614.1\|986780_987176_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_001217728.1\|987546_988266_+	adaptor protein MecA	NA	NA	NA	NA
WP_000959292.1\|988386_989373_+	competence protein CoiA	NA	NA	NA	NA
WP_000082725.1\|989420_991229_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	5.5e-47	24.5
WP_001808146.1\|991518_992838_-\|transposase	ISL3-like element IS1181 family transposase	NA	NA	NA	NA
WP_000214070.1\|994038_994404_-	truncated hemoglobin	NA	NA	NA	NA
WP_000224612.1\|994507_995101_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_001242102.1\|995286_995634_+	hypothetical protein	NA	NA	NA	NA
WP_001077683.1\|995650_996286_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_001270834.1\|996302_997112_+	NAD kinase	NA	NA	NA	NA
WP_000669934.1\|997108_997963_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_111688616.1\|997983_999369_+	magnesium transporter	NA	NA	NA	NA
WP_000395153.1\|999378_1001223_+	monovalent cation:proton antiporter family protein	NA	NA	NA	NA
WP_000933195.1\|1001500_1002271_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_000933105.1\|1002467_1003553_-	AI-2E family transporter	NA	NA	NA	NA
WP_000570687.1\|1003894_1005463_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_001288675.1\|1005607_1006366_+	esterase family protein	NA	NA	NA	NA
WP_000600387.1\|1006559_1007069_+	2'-5' RNA ligase family protein	NA	NA	NA	NA
WP_001154224.1\|1007181_1008372_-	MFS transporter	NA	NA	NA	NA
WP_000258645.1\|1008349_1009525_-	diglucosyl diacylglycerol synthase	NA	NA	NA	NA
WP_000340119.1\|1009957_1011442_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
WP_001795833.1\|1011422_1011683_+	YueH family protein	NA	NA	NA	NA
WP_001049951.1\|1011682_1013245_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	1.7e-36	28.2
WP_000928413.1\|1013546_1014350_+	TerC family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
WP_001795272.1\|1014568_1016893_+\|protease	serine protease	W5SAB9	Pithovirus	2.8e-11	27.4
WP_000021865.1\|1016909_1018268_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000414165.1\|1018406_1019918_+	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000287265.1\|1020404_1020974_-	competence protein ComK	NA	NA	NA	NA
WP_000876826.1\|1021183_1021402_+	IDEAL domain-containing protein	NA	NA	NA	NA
WP_000668818.1\|1021482_1022469_-	lipoate--protein ligase	NA	NA	NA	NA
WP_000214898.1\|1022667_1022844_+	YkvS family protein	NA	NA	NA	NA
WP_001033865.1\|1022858_1023461_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_031763719.1\|1024375_1024477_+	hypothetical protein	NA	NA	NA	NA
WP_001797239.1\|1024486_1024759_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000870827.1\|1024802_1026767_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000668627.1\|1026769_1027090_+	YxeA family protein	NA	NA	NA	NA
WP_000571167.1\|1027086_1027728_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-19	33.0
WP_001795266.1\|1027815_1028106_-	hypothetical protein	NA	NA	NA	NA
WP_001792054.1\|1028246_1028384_+	poly(glycerol-phosphate) alpha-glucosyltransferase	NA	NA	NA	NA
WP_000766009.1\|1028472_1028829_-	DoxX family protein	NA	NA	NA	NA
WP_001081351.1\|1029316_1030276_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001790177.1\|1030321_1030453_-	hypothetical protein	NA	NA	NA	NA
WP_000867357.1\|1030516_1030732_-	TM2 domain-containing protein	A0A060AN66	Enterococcus_phage	1.5e-07	49.1
WP_000620949.1\|1030896_1031448_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000070966.1\|1031499_1032438_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_000190622.1\|1032619_1033981_+	isochorismate synthase MenF	NA	NA	NA	NA
WP_000526694.1\|1033967_1035641_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_000150197.1\|1035627_1036431_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_000184945.1\|1036423_1037245_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_000284458.1\|1037482_1037812_-	staphostatin B	NA	NA	NA	NA
WP_001089094.1\|1037849_1039031_-\|protease	cysteine protease staphopain B	NA	NA	NA	NA

DBSCAN-SWA_6

1059075 : 1067548

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1059075_1059558_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_001010407.1\|1059544_1060669_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1060672_1061377_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1061376_1061640_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666806.1\|1061641_1062313_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_111688617.1\|1062305_1064495_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.5e-141	39.8
WP_000483720.1\|1064473_1065958_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.9e-45	31.7
WP_000030811.1\|1065950_1066979_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
WP_111688618.1\|1066981_1067548_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.3e-28	39.6

DBSCAN-SWA_7

1325070 : 1341274

Staphylococcus_phage(54.17%)

terminase,integrase,capsid,portal

attL 1318794:1318811|attR 1344118:1344135

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1318794:1318811	attL	NA	NA	NA	NA
WP_001836882.1\|1325070_1326198_-\|integrase	site-specific integrase	A0A0C5AN64	Paenibacillus_phage	6.2e-33	31.4
WP_001183750.1\|1326250_1326946_-	Ltp family lipoprotein	A0A2H4J5B8	uncultured_Caudovirales_phage	3.6e-07	50.3
WP_000554410.1\|1326957_1327341_-	hypothetical protein	NA	NA	NA	NA
WP_000664917.1\|1327487_1327880_-	helix-turn-helix domain-containing protein	A0A2I6PE55	Staphylococcus_phage	1.6e-28	53.6
WP_001209962.1\|1328047_1328266_+	DUF739 family protein	A0A2I6PE94	Staphylococcus_phage	4.9e-19	62.5
WP_000932238.1\|1328292_1328568_+	hypothetical protein	NA	NA	NA	NA
WP_000392387.1\|1328832_1329003_+	hypothetical protein	Q4ZDZ8	Staphylococcus_virus	2.4e-21	89.3
WP_000800341.1\|1328991_1329198_-	hypothetical protein	A1BTY8	Staphylococcus_virus	3.3e-25	75.0
WP_001157025.1\|1329258_1329942_+	phage repressor protein	A9CR56	Staphylococcus_phage	5.2e-107	85.6
WP_000072840.1\|1330040_1330202_+	DUF1270 family protein	R4IH12	Staphylococcus_phage	1.1e-12	69.8
WP_111688634.1\|1330288_1330606_+	DUF2482 family protein	W5RAK4	Staphylococcus_phage	1.6e-26	68.1
WP_000786634.1\|1330595_1330862_+	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	3.0e-18	53.6
WP_001004327.1\|1330866_1331403_+	host-nuclease inhibitor Gam family protein	A0A0H3U480	Staphylococcus_phage	1.7e-76	82.5
WP_000907597.1\|1331403_1332183_+	ATP-binding protein	A0A1W6JPW0	Staphylococcus_phage	2.3e-127	88.0
WP_000702007.1\|1332209_1332758_+	hypothetical protein	A7TWM8	Staphylococcus_phage	1.1e-91	92.9
WP_000929466.1\|1332770_1333673_+	DnaD domain protein	A0A1P8L6F0	Staphylococcus_phage	2.9e-49	52.0
WP_000946005.1\|1333673_1333964_+	hypothetical protein	A0A223LIA9	Staphylococcus_phage	7.2e-18	58.1
WP_000714410.1\|1333978_1334143_+	hypothetical protein	A0A0E3T9L7	Staphylococcus_phage	1.1e-18	88.9
WP_000860979.1\|1334142_1334454_+	hypothetical protein	NA	NA	NA	NA
WP_000185176.1\|1334446_1334977_+	nucleotide pyrophosphohydrolase	A0A1P8VVP1	Streptococcus_phage	5.2e-22	38.2
WP_025174970.1\|1335118_1335226_+	DUF1381 domain-containing protein	C8CH06	Staphylococcus_phage	3.2e-08	87.5
WP_000835355.1\|1335222_1335687_+	hypothetical protein	C9E2P0	Enterococcus_phage	3.2e-20	43.0
WP_111688635.1\|1335963_1336452_+	RNA polymerase subunit sigma-70	R9TMH4	Paenibacillus_phage	9.7e-07	27.7
WP_000090969.1\|1336604_1337033_+	helix-turn-helix domain-containing protein	A1EAE0	Streptococcus_phage	1.1e-25	45.1
WP_000207537.1\|1337019_1338294_+\|terminase	PBSX family phage terminase large subunit	Q4ZE37	Staphylococcus_virus	1.9e-195	76.4
WP_000158568.1\|1338306_1339755_+\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	7.4e-196	69.4
WP_001282612.1\|1339744_1341274_+\|capsid	minor capsid protein	Q4ZE35	Staphylococcus_virus	1.9e-109	61.6
1344118:1344135	attR	NA	NA	NA	NA

DBSCAN-SWA_8

1619228 : 1627558

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1619228_1620014_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924220.1\|1620139_1621030_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062187.1\|1621039_1622386_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683929.1\|1622499_1623600_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624583.1\|1623602_1624280_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1624410_1625517_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217257.1\|1625740_1627558_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.3

DBSCAN-SWA_9

1695392 : 1704435

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1695392_1695911_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594991.1\|1695932_1698206_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	5.2e-63	28.8
WP_000749795.1\|1698408_1700688_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1700962_1701223_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1701241_1702381_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1702403_1703429_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1703430_1704435_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_10

1839821 : 1873997

Staphylococcus_phage(93.75%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001025061.1\|1839821_1841003_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
WP_000526539.1\|1841112_1842066_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000266096.1\|1842458_1843286_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1843288_1843408_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1843519_1844521_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008551.1\|1844642_1845107_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
WP_001159022.1\|1845119_1846301_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
WP_000493892.1\|1846311_1846944_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
WP_000077358.1\|1846950_1847994_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
WP_001261668.1\|1848474_1849977_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1\|1850499_1850814_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989122.1\|1850813_1852106_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	9.4e-227	99.3
WP_001032833.1\|1852192_1853047_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1853322_1853547_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1853745_1854216_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1854328_1854772_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1854758_1855202_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168901.1\|1855497_1856133_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1856572_1857286_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1857545_1857848_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1858103_1858469_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623478.1\|1858465_1858819_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.6e-22	100.0
WP_000453314.1\|1859201_1860035_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366163.1\|1860246_1861155_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933822.1\|1861279_1862473_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109906.1\|1862844_1864437_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_001834463.1\|1864814_1865561_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000672014.1\|1865565_1866039_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	4.7e-83	98.1
WP_000718107.1\|1866104_1866362_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778525.1\|1866358_1867360_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.2e-186	97.9
WP_000348374.1\|1867364_1868843_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	8.1e-283	97.4
WP_072433592.1\|1869001_1869457_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.9
WP_001795535.1\|1869759_1870410_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.7e-44	88.4
WP_000070655.1\|1870490_1871486_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	6.2e-77	98.8
WP_000669027.1\|1871561_1872188_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	5.3e-90	93.8
WP_000627537.1\|1872228_1872570_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	3.0e-55	95.6
WP_000414214.1\|1872670_1873243_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.1e-25	96.6
WP_000864143.1\|1873439_1873997_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4PQN8	Staphylococcus_phage	2.7e-77	96.2

DBSCAN-SWA_11

1883191 : 1891016

Staphylococcus_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000072589.1\|1883191_1884400_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	9.3e-35	31.5
WP_000028671.1\|1884392_1885949_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	2.6e-287	98.3
WP_001791797.1\|1886112_1886247_-	hypothetical protein	NA	NA	NA	NA
WP_017431874.1\|1886311_1887031_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.7e-129	97.9
WP_001038872.1\|1887151_1887871_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001039444.1\|1887928_1888651_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001039433.1\|1888775_1889483_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_001092776.1\|1890446_1891016_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	2.6e-51	62.6

DBSCAN-SWA_12

2041486 : 2053273

Staphylococcus_phage(82.35%)

terminase,integrase,coat

attL 2037369:2037388|attR 2051295:2051314

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2037369:2037388	attL	NA	NA	NA	NA
WP_001293079.1\|2041486_2042056_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	6.6e-100	97.4
WP_072326620.1\|2042052_2042265_-	pathogenicity island family protein	Q4ZE86	Staphylococcus_phage	5.1e-29	88.6
WP_001836980.1\|2042396_2042924_-\|coat	spore coat protein	Q4ZE87	Staphylococcus_phage	3.7e-89	97.1
WP_000448775.1\|2042974_2043193_-	hypothetical protein	NA	NA	NA	NA
WP_000846292.1\|2043210_2043789_-	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	1.6e-29	39.5
WP_001161659.1\|2043800_2044142_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	2.1e-56	96.5
WP_001019765.1\|2044488_2045130_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	7.2e-111	93.0
WP_001149387.1\|2045131_2045404_-	hypothetical protein	Q4ZE68	Staphylococcus_phage	3.2e-44	100.0
WP_000148374.1\|2045390_2046194_-	bifunctional DNA primase/polymerase	Q4ZE69	Staphylococcus_phage	6.2e-152	97.0
WP_111688665.1\|2046369_2047986_-	phage resistance protein	A0A1W6JPF4	Staphylococcus_phage	6.9e-243	76.8
WP_001103943.1\|2048060_2048360_-	DUF1474 family protein	A0A1W6JQH0	Staphylococcus_phage	6.1e-20	58.2
WP_001058486.1\|2048362_2048572_-	hypothetical protein	Q4ZE76	Staphylococcus_phage	1.7e-29	94.2
WP_000784875.1\|2048564_2048711_-	hypothetical protein	NA	NA	NA	NA
WP_000459698.1\|2048707_2049025_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	8.6e-49	94.3
WP_000794315.1\|2049028_2049241_-	helix-turn-helix transcriptional regulator	A0A1W6JQE8	Staphylococcus_phage	3.8e-24	84.1
WP_000616253.1\|2049414_2050047_+	helix-turn-helix transcriptional regulator	A0A1W6JQE6	Staphylococcus_phage	2.2e-96	82.9
WP_000179352.1\|2050055_2051228_+\|integrase	tyrosine-type recombinase/integrase	A0A1W6JQD3	Staphylococcus_phage	5.9e-220	98.2
WP_000240645.1\|2051296_2052913_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
2051295:2051314	attR	NA	NA	NA	NA
WP_000917289.1\|2052988_2053273_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483314

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection