CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483331	Streptococcus pyogenes strain NCTC12057 chromosome 1	2 crisprs	DinG,csm6,RT,cas3,DEDDh,csa3	0	1	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483331_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483331_1

798809-799027

Orphan

II-A

Consensus_repeat	Method
TGTTTTGAATGGTCCCAAAAC	CRT

3 spacers

The CRISPR arrays of NZ_LS483331_1

>merge|NZ_LS483331|1|798809-799027|CRT
TGTTTTGAATGGTCCCAAAACGATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGTTGTGTTGAATGGTCCCAAAACCAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGTTGTTTTGAATGGTCCCAAAACGCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGCTGTTTTGAATGGTCTCCATTC

>NZ_LS483331|1|1|798809-799027|CRT
TGTTTTGAATGGTCCCAAAAC	GATTAGCTCAAGCATGCCTTTATAAATGTCGTTTTAGAGCTATGT
TGTGTTGAATGGTCCCAAAAC	CAGCTTGGATTTAATAGCAGACCATGTTTTGTTTTAGAGCTATGT
TGTTTTGAATGGTCCCAAAAC	GCACGAGTTTAACTCCCTTATTATTAGCTTGTTTTAGAGCTATGC
TGTTTTGAATGGTCTCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483331.1\|WP_023612035.1\|803951_804971_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483331.1\|WP_023079409.1\|807906_809556_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483331.1\|WP_023611966.1\|803384_803822_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483331.1\|WP_023611962.1\|795352_796483_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483331.1\|WP_002984858.1\|791311_792163_+\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NZ_LS483331.1\|WP_002984845.1\|805629_806121_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483331.1\|WP_002989931.1\|806943_807771_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483331.1\|WP_050336191.1\|796492_797245_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483331.1\|WP_011106808.1\|793169_794525_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483331.1\|WP_023080006.1\|794648_795290_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483331.1\|WP_023611142.1\|797244_798009_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483331.1\|WP_023612042.1\|798008_798641_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483331.1\|WP_023612009.1\|799670_801503_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483331.1\|WP_002989935.1\|805177_805603_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483331.1\|WP_020905130.1\|789070_789862_-\|type-1-glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NZ_LS483331.1\|WP_023611114.1\|789861_791205_-\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|223840
NZ_LS483331.1\|WP_002984836.1\|809559_810348_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483331.1\|WP_002984833.1\|810341_811388_+\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270264
NZ_LS483331.1\|WP_011054410.1\|792159_793116_+\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LS483331.1\|WP_002984844.1\|806137_806947_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238

Protein	Function_ID	Function_description	E-value
NZ_LS483331.1\|WP_023612035.1\|803951_804971_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	6.6919e-100
NZ_LS483331.1\|WP_023079409.1\|807906_809556_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.69316e-77
NZ_LS483331.1\|WP_023611966.1\|803384_803822_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.35343e-84
NZ_LS483331.1\|WP_023611962.1\|795352_796483_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483331.1\|WP_002984858.1\|791311_792163_+\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.09715e-101
NZ_LS483331.1\|WP_002989931.1\|806943_807771_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483331.1\|WP_050336191.1\|796492_797245_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.74349e-109
NZ_LS483331.1\|WP_011106808.1\|793169_794525_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483331.1\|WP_002984845.1\|805629_806121_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	2.00329e-54
NZ_LS483331.1\|WP_023611142.1\|797244_798009_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	6.49715e-128
NZ_LS483331.1\|WP_023612042.1\|798008_798641_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	2.38885e-87
NZ_LS483331.1\|WP_023612009.1\|799670_801503_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483331.1\|WP_002989935.1\|805177_805603_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.64459e-31
NZ_LS483331.1\|WP_020905130.1\|789070_789862_-\|type-1-glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	6.74846e-142
NZ_LS483331.1\|WP_023611114.1\|789861_791205_-\|Mur-ligase-family-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.97423e-110
NZ_LS483331.1\|WP_002984836.1\|809559_810348_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_LS483331.1\|WP_002984833.1\|810341_811388_+\|extracellular-solute-binding-protein	gnl\|CDD\|270264	cd13546, PBP2_BitB, Substrate binding domain of a putative iron transporter BitB, a member of the type 2 periplasmic binding fold superfamily. The substrate domain of this group shows a high homology to the periplasmic component of ferric iron transporter (Fbp), but its biochemical characterization has not been performed. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.52289e-91
NZ_LS483331.1\|WP_011054410.1\|792159_793116_+\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	1.65904e-113
NZ_LS483331.1\|WP_002984844.1\|806137_806947_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.81104e-76

>NZ_LS483331.1|WP_023612042.1|798008_798641_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHKVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARRQRLNVE
>NZ_LS483331.1|WP_023611142.1|797244_798009_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLAKQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483331.1|WP_050336191.1|796492_797245_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNILVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILSYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>NZ_LS483331.1|WP_023611962.1|795352_796483_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483331.1|WP_023080006.1|794648_795290_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483331.1|WP_011106808.1|793169_794525_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LS483331.1|WP_011054410.1|792159_793116_+|YbbR-like-domain-containing-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVDKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK
>NZ_LS483331.1|WP_002984858.1|791311_792163_+|TIGR00159-family-protein
MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALTGTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEKFGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPLNADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAIGLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVTLPWYKKILGGKSK
>NZ_LS483331.1|WP_023611114.1|789861_791205_-|Mur-ligase-family-protein
MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDLSKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKSGRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPKATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNTYANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALAAVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQLADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVTGFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI
>NZ_LS483331.1|WP_020905130.1|789070_789862_-|type-1-glutamine-amidotransferase
MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVAEKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNKVVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYYGFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLAYRLVTTALKKKYGSAISLSSYDDILKQEITEEYADLKSKASFNKV
>NZ_LS483331.1|WP_023612009.1|799670_801503_+|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDTSEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK
>NZ_LS483331.1|WP_023611966.1|803384_803822_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRIEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_LS483331.1|WP_023612035.1|803951_804971_+|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALSAWYLGRLFPIIGAPVFAILLGMLLALFYEHGDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALLVAYGSQKWLRLDVNTATLVGIGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLIGLSNEGFATFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYQAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483331.1|WP_002989935.1|805177_805603_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483331.1|WP_002984845.1|805629_806121_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483331.1|WP_002984844.1|806137_806947_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA
>NZ_LS483331.1|WP_002989931.1|806943_807771_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483331.1|WP_023079409.1|807906_809556_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483331.1|WP_002984836.1|809559_810348_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC
>NZ_LS483331.1|WP_002984833.1|810341_811388_+|extracellular-solute-binding-protein
MLKLKRKWLLSFLLVIIILAIVNVAMYIFSSSKKDSAKELVILTPNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFESHKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQPALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDVYESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAKQFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKILNTYNRLHEALERGK

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Crispr_ID: NZ_LS483331_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483331_2

1286382-1286475

Unclear

Consensus_repeat	Method
AATCCACTCACCCGTGAAGGGTGAGAC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NZ_LS483331_2

>merge|NZ_LS483331|2|1286382-1286475|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGACCTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTTAATCCACTCACCCGTGAAGGGTGAGAC

>NZ_LS483331|2|1|1286382-1286475|CRISPRCasFinder
AATCCACTCACCCGTGAAGGGTGAGAC	CTAGTGGCTATGCGGAGTTACTTATCCAACTGATTATTTT
AATCCACTCACCCGTGAAGGGTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483331.1\|WP_023612487.1\|1285291_1286251_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LS483331.1\|WP_050336302.1\|1286825_1288073_-\|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483331.1\|WP_023612521.1\|1281551_1282658_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483331.1\|WP_002989056.1\|1276471_1276945_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483331.1\|WP_023612512.1\|1282700_1283324_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483331.1\|WP_002983781.1\|1280723_1281464_-\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483331.1\|WP_023612491.1\|1275649_1276330_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483331.1\|WP_023612053.1\|1293992_1295066_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|273575
NZ_LS483331.1\|WP_002983741.1\|1295808_1296147_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380358
NZ_LS483331.1\|WP_023612502.1\|1292040_1292436_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_LS483331.1\|WP_023612518.1\|1288226_1290875_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483331.1\|WP_002989010.1\|1296199_1296955_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NZ_LS483331.1\|WP_002983750.1\|1292453_1292708_-\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073
NZ_LS483331.1\|WP_002983746.1\|1293184_1293937_+\|3-deoxy-7-phosphoheptulonate-synthase	unknown	unknown	gnl\|CDD\|172030
NZ_LS483331.1\|WP_011018021.1\|1284267_1285200_-\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361
NZ_LS483331.1\|WP_023612499.1\|1278993_1280727_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483331.1\|WP_023612519.1\|1277841_1278921_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483331.1\|WP_011888719.1\|1290876_1291440_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_LS483331.1\|WP_002983743.1\|1295501_1295807_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380388
NZ_LS483331.1\|WP_023612523.1\|1283336_1284047_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856

Protein	Function_ID	Function_description	E-value
NZ_LS483331.1\|WP_023612487.1\|1285291_1286251_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	4.87701e-56
NZ_LS483331.1\|WP_050336302.1\|1286825_1288073_-\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	5.35517e-59
NZ_LS483331.1\|WP_023612521.1\|1281551_1282658_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	2.3863e-163
NZ_LS483331.1\|WP_002989056.1\|1276471_1276945_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.68589e-66
NZ_LS483331.1\|WP_023612512.1\|1282700_1283324_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.7195e-35
NZ_LS483331.1\|WP_002983781.1\|1280723_1281464_-\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.85886e-83
NZ_LS483331.1\|WP_023612491.1\|1275649_1276330_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.96742e-40
NZ_LS483331.1\|WP_023612053.1\|1293992_1295066_+\|3-dehydroquinate-synthase	gnl\|CDD\|273575	TIGR01357, 3-dehydroquinate_synthase, 3-dehydroquinate synthase. This model represents 3-dehydroquinate synthase, the enzyme catalyzing the second of seven steps in the shikimate pathway of chorismate biosynthesis. Chorismate is the last common intermediate in the biosynthesis of all three aromatic amino acids. [Amino acid biosynthesis, Aromatic amino acid family].	9.25661e-164
NZ_LS483331.1\|WP_002983741.1\|1295808_1296147_-\|cupin-domain-containing-protein	gnl\|CDD\|380358	cd02230, cupin_HP0902-like, Helicobacter pylori HP0902 and related proteins, cupin domain. This family includes prokaryotic and archaeal proteins homologous to HP0902, a functionally uncharacterized protein from Helicobacter pylori and Spy1581, a protein of unknown function from Streptococcus pyogenes. These proteins demonstrate all-beta cupin folds that cannot bind metal ions due to the absence of a metal-binding histidine that is conserved in many metallo-cupins. HP0902 is able to bind bacterial endotoxin lipopolysaccharides (LPS) through its surface-exposed loops, where metal-binding sites are usually found in other metallo-cupins, and thus may have a putative role in H. pylori pathogenicity.	1.59437e-37
NZ_LS483331.1\|WP_023612502.1\|1292040_1292436_-\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000143012
NZ_LS483331.1\|WP_023612518.1\|1288226_1290875_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483331.1\|WP_002989010.1\|1296199_1296955_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.89764e-26
NZ_LS483331.1\|WP_002983750.1\|1292453_1292708_-\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
NZ_LS483331.1\|WP_002983746.1\|1293184_1293937_+\|3-deoxy-7-phosphoheptulonate-synthase	gnl\|CDD\|172030	PRK13397, PRK13397, 3-deoxy-7-phosphoheptulonate synthase; Provisional.	0
NZ_LS483331.1\|WP_011018021.1\|1284267_1285200_-\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.35313e-79
NZ_LS483331.1\|WP_023612499.1\|1278993_1280727_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	2.08305e-64
NZ_LS483331.1\|WP_023612519.1\|1277841_1278921_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	2.00918e-35
NZ_LS483331.1\|WP_011888719.1\|1290876_1291440_-\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00452424
NZ_LS483331.1\|WP_002983743.1\|1295501_1295807_-\|cupin-domain-containing-protein	gnl\|CDD\|380388	cd06983, cupin_dsy2733, Desulfitobacterium hafniense dsy2733 and related proteins, cupin domain. This family includes bacterial proteins homologous to dsy2733, a Desulfitobacterium hafniense protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.13368e-18
NZ_LS483331.1\|WP_023612523.1\|1283336_1284047_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	6.4437e-43

>NZ_LS483331.1|WP_023612487.1|1285291_1286251_-|Gfo/Idh/MocA-family-oxidoreductase
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFAAAHQLPKAYGSLDDMLLDASIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTQRLKGLIAAVELGDIVSVSSTTAYPNIDHVTWFRDLEKGGGTVHFMAPYALSYLPYLFDADIVSASGVAHFPKGQSDSQSKLVLTLSNGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKNTHATLVRPDGSRSVIEAIMSSDFEAEAHHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>NZ_LS483331.1|WP_011018021.1|1284267_1285200_-|magnesium-transporter-CorA-family-protein
MPTLPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDKNETSFMEENKEKLTIVFQILDRQEEAYHPNYIPRVIPITLFLNDQSLYILGHDHSLTLIEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLESLANLQSGTVYILMGSKQNEQMLAELKDMPGQQDLEEDEAEQLRDAIIEARQLSNMCDLNTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSVWFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI
>NZ_LS483331.1|WP_023612523.1|1283336_1284047_-|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483331.1|WP_023612512.1|1282700_1283324_-|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMTDKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483331.1|WP_023612521.1|1281551_1282658_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483331.1|WP_002983781.1|1280723_1281464_-|response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_LS483331.1|WP_023612499.1|1278993_1280727_-|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGKGIEDSSLTNSQSLLTRGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_LS483331.1|WP_023612519.1|1277841_1278921_-|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_LS483331.1|WP_002989056.1|1276471_1276945_+|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483331.1|WP_023612491.1|1275649_1276330_-|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVISGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_LS483331.1|WP_050336302.1|1286825_1288073_-|CRISPR-associated-endonuclease-Cas3''
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEIVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQVNEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLIKVDKRLFEFFIVAFNC
>NZ_LS483331.1|WP_023612518.1|1288226_1290875_-|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_LS483331.1|WP_011888719.1|1290876_1291440_-|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483331.1|WP_023612502.1|1292040_1292436_-|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKDSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_LS483331.1|WP_002983750.1|1292453_1292708_-|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>NZ_LS483331.1|WP_002983746.1|1293184_1293937_+|3-deoxy-7-phosphoheptulonate-synthase
MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYNYFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVIQVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGVRGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMMEVHPDPDHALSDAAQQIDYKQLEQLGQELWQD
>NZ_LS483331.1|WP_023612053.1|1293992_1295066_+|3-dehydroquinate-synthase
MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQTVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIGGGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPEAIIISTTFLETLPQREFSCGISEMLKIGFIHNRPLFQQLRDFQKETDKQGLERLIYQSISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAVSKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTETGFTTLAINKDDHQFVEKLDSLL
>NZ_LS483331.1|WP_002983743.1|1295501_1295807_-|cupin-domain-containing-protein
MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD
>NZ_LS483331.1|WP_002983741.1|1295808_1296147_-|cupin-domain-containing-protein
MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSLDKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQMLLVVVKPEA
>NZ_LS483331.1|WP_002989010.1|1296199_1296955_-|class-I-SAM-dependent-methyltransferase
MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLEVACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPFPDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDELRQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRRGLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483331_2	2.1\|1286409\|40\|NZ_LS483331\|CRISPRCasFinder	1286409-1286448	40	MK448679	Streptococcus phage Javan137, complete genome	35066-35105	8	0.8
NZ_LS483331_2	2.1\|1286409\|40\|NZ_LS483331\|CRISPRCasFinder	1286409-1286448	40	MK448950	Streptococcus phage Javan464, complete genome	37224-37263	9	0.775

1. spacer 2.1|1286409|40|NZ_LS483331|CRISPRCasFinder matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 8, identity: 0.8

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
ctagtggctatgcggagttacttatccaaattatcgagga	Protospacer
***************************** * **..

2. spacer 2.1|1286409|40|NZ_LS483331|CRISPRCasFinder matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 9, identity: 0.775

ctagtggctatgcggagttacttatccaactgattatttt	CRISPR spacer
cgagtggctatgcggagttgcttatccaactaatcgagga	Protospacer
* *****************.***********.**..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36638 : 48950

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023612102.1\|36638_40364_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.1e-40	26.8
WP_023612105.1\|40524_41979_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	33.3
WP_023612098.1\|42006_43029_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	4.0e-63	41.5
WP_002986700.1\|43196_43751_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_023612109.1\|43934_45482_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_010921776.1\|45538_46663_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_023612108.1\|46915_48181_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_023612097.1\|48458_48950_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.8e-19	43.1

DBSCAN-SWA_2

346471 : 352506

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002990917.1\|346471_347107_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.7e-65	63.4
WP_002985844.1\|347124_348000_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
WP_002985838.1\|348662_348986_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_021733048.1\|348990_349854_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	74.7
WP_002985833.1\|349880_350273_+	hypothetical protein	NA	NA	NA	NA
WP_009880724.1\|350319_350949_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_011284536.1\|351248_351605_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.3e-40	65.8
WP_023078944.1\|351678_352506_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	3.8e-128	79.5

DBSCAN-SWA_3

647559 : 658163

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044559748.1\|647559_649770_-	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9
WP_023612435.1\|649877_651041_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|651037_651724_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002990262.1\|651817_652984_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002990260.1\|653044_653386_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.6e-19	41.1
WP_023612440.1\|653607_654960_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	5.9e-30	24.7
WP_002990257.1\|655047_656316_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012560601.1\|656345_656786_-	hypothetical protein	NA	NA	NA	NA
WP_011184383.1\|657020_658163_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3

DBSCAN-SWA_4

958078 : 1032795

Streptococcus_phage(52.24%)

capsid,protease,head,holin,integrase,tRNA,tail,portal,terminase

attL 991431:991490|attR 1032838:1032933

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023612481.1\|958078_958963_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_023612473.1\|959078_960419_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_023612470.1\|960515_961472_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_002993908.1\|961482_962079_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_023612475.1\|962170_964807_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_023612464.1\|964821_965523_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	37.0
WP_023612443.1\|965640_966183_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|966325_966967_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023612454.1\|967129_967618_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_023612456.1\|967628_967829_-	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	51.5
WP_002984475.1\|967869_968409_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984473.1\|968421_968610_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984470.1\|968620_969232_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|969268_969517_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_023612212.1\|969879_972198_-	DNA helicase PcrA	A7KV33	Bacillus_phage	2.3e-130	40.9
WP_023612223.1\|972726_974049_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_023612209.1\|974168_975404_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_023612220.1\|975773_976547_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_002989634.1\|976916_977753_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023612213.1\|977768_978398_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-27	35.5
WP_002992417.1\|978407_979049_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002989626.1\|979155_979491_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_023612218.1\|979686_981501_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	6.8e-98	38.6
WP_023612216.1\|981676_982234_-	signal peptidase I	NA	NA	NA	NA
WP_002984447.1\|982451_983954_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|984016_985030_-	6-phosphofructokinase	NA	NA	NA	NA
WP_023612222.1\|985109_988220_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	8.3e-120	29.9
WP_002989617.1\|988404_988776_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002984437.1\|988775_989474_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|989483_990269_+	hypothetical protein	NA	NA	NA	NA
WP_023612208.1\|990395_991010_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	4.0e-50	51.8
991431:991490	attL	NA	NA	NA	NA
WP_032461628.1\|991600_991789_-	hypothetical protein	A3F673	Streptococcus_phage	6.5e-20	81.4
WP_011184727.1\|992028_992787_+	DNase Mf2	NA	NA	NA	NA
WP_021733756.1\|992897_993605_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	5.1e-09	26.7
WP_023611694.1\|993673_994426_-	SH3 domain-containing protein	A3F665	Streptococcus_phage	2.1e-141	97.2
WP_021733507.1\|994427_994760_-\|holin	phage holin	A3F664	Streptococcus_phage	2.8e-50	98.2
WP_021733504.1\|994772_995093_-	hypothetical protein	A3F663	Streptococcus_phage	1.2e-50	99.1
WP_032461629.1\|995103_995715_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.1e-84	93.6
WP_002987513.1\|995717_996149_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_032461630.1\|996160_998044_-	gp58-like family protein	Q938J9	Temperate_phage	8.0e-251	96.5
WP_032461631.1\|998058_999072_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	9.5e-182	98.5
WP_032461632.1\|999068_1001213_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	98.2
WP_024623478.1\|1001209_1001917_-	hypothetical protein	Q938K2	Temperate_phage	1.7e-92	70.6
WP_032461633.1\|1001916_1005840_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	2.6e-243	49.1
WP_021299462.1\|1005852_1006002_-	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_021733367.1\|1006049_1006376_-	hypothetical protein	J7KK85	Streptococcus_phage	6.4e-39	75.0
WP_021341058.1\|1006428_1007040_-\|tail	phage major tail protein	J7KKC8	Streptococcus_phage	1.8e-74	73.0
WP_021341057.1\|1007056_1007482_-	hypothetical protein	J7KBZ9	Streptococcus_phage	2.9e-68	85.8
WP_021340627.1\|1007478_1007856_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	73.6
WP_029714354.1\|1007852_1008200_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.1e-48	84.5
WP_021341088.1\|1008196_1008499_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	2.6e-42	87.8
WP_021341090.1\|1008643_1009828_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.2e-162	76.1
WP_021341143.1\|1009851_1010517_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	5.4e-93	78.6
WP_032461634.1\|1010494_1011715_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	3.4e-186	81.7
WP_002985363.1\|1011748_1011973_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1011965_1012136_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_032461635.1\|1012132_1013887_-\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	96.2
WP_002985371.1\|1013901_1014369_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_021340284.1\|1014536_1014878_-	HNH endonuclease	J7KH36	Streptococcus_phage	2.5e-54	90.7
WP_032461637.1\|1015475_1015910_-	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	2.2e-71	94.4
WP_002987493.1\|1016192_1016363_-	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_032461638.1\|1016359_1016863_-	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	1.5e-92	99.4
WP_032461639.1\|1016859_1017153_-	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	4.2e-50	100.0
WP_011054812.1\|1017149_1017335_-	hypothetical protein	A0A097PBF0	Streptococcus_pyogenes_phage	7.0e-27	100.0
WP_021733098.1\|1017359_1017548_-	hypothetical protein	A0A097PAU8	Streptococcus_pyogenes_phage	1.2e-13	97.1
WP_011054813.1\|1017550_1017886_-	hypothetical protein	A0A097PAS4	Streptococcus_pyogenes_phage	4.7e-45	100.0
WP_032461310.1\|1017888_1018173_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	5.0e-40	91.5
WP_164977039.1\|1018169_1018340_-	hypothetical protein	Q938M0	Temperate_phage	8.5e-11	100.0
WP_011054815.1\|1018336_1018750_-	hypothetical protein	Q938M1	Temperate_phage	1.2e-34	63.1
WP_032461640.1\|1018746_1019031_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	1.3e-48	96.8
WP_011018138.1\|1019272_1019629_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_011018139.1\|1019625_1020066_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	1.6e-80	98.6
WP_011106686.1\|1020065_1020269_-	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_021341162.1\|1020274_1020766_-	single-stranded DNA-binding protein	A0A286QNX2	Streptococcus_phage	7.6e-60	74.2
WP_021340879.1\|1020758_1021433_-	ERF family protein	Q938M8	Temperate_phage	2.0e-103	96.9
WP_021341163.1\|1021433_1021916_-	siphovirus Gp157 family protein	Q938M9	Temperate_phage	1.6e-49	98.8
WP_021341161.1\|1021937_1022192_-	hypothetical protein	Q938N0	Temperate_phage	6.3e-42	97.6
WP_021341157.1\|1022172_1022529_-	HTH domain-containing protein	A0A097PAU3	Streptococcus_pyogenes_phage	3.0e-50	99.2
WP_011018145.1\|1022539_1022677_-	hypothetical protein	J7KBQ4	Streptococcus_phage	2.7e-07	78.4
WP_021341158.1\|1022667_1023450_-	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	2.7e-144	98.1
WP_021340639.1\|1023436_1024240_-	DnaD domain protein	A0A2P0VI76	Streptococcus_phage	2.4e-63	53.8
WP_012560973.1\|1024355_1024799_-	hypothetical protein	NA	NA	NA	NA
WP_000568478.1\|1024854_1025235_+	hypothetical protein	NA	NA	NA	NA
WP_000370473.1\|1025224_1025497_-	hypothetical protein	NA	NA	NA	NA
WP_012560974.1\|1025669_1025849_-	hypothetical protein	A0A1X9I5M8	Streptococcus_phage	1.2e-12	65.5
WP_021733370.1\|1026110_1026407_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	1.2e-47	96.9
WP_021341082.1\|1026542_1026686_+	hypothetical protein	M1PFC9	Streptococcus_phage	2.4e-11	72.3
WP_021341081.1\|1026848_1027088_-	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	9.1e-35	96.2
WP_014635527.1\|1027181_1027853_+	DUF4145 domain-containing protein	A0A1S5S8U0	Streptococcus_phage	7.0e-40	39.9
WP_014635529.1\|1027969_1028128_-	hypothetical protein	J7KH24	Streptococcus_phage	1.3e-21	90.4
WP_014635530.1\|1028186_1028402_+	hypothetical protein	J7KBX0	Streptococcus_phage	8.8e-29	97.1
WP_014635531.1\|1028387_1028537_-	hypothetical protein	J7KH12	Streptococcus_phage	9.7e-19	89.8
WP_021341138.1\|1028907_1029696_+	peptidase S24	A0A1S5SD15	Streptococcus_phage	1.4e-87	63.8
WP_021341136.1\|1029774_1030671_+	ATP-binding protein	NA	NA	NA	NA
WP_021341135.1\|1030685_1031045_+	STAS-like domain-containing protein	NA	NA	NA	NA
WP_021341137.1\|1031041_1031587_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_021341141.1\|1031706_1032795_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	7.2e-204	99.7
1032838:1032933	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483331

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection