CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483330	Streptococcus pyogenes strain NCTC8328 chromosome 1	3 crisprs	DEDDh,cas3,csn2,cas2,cas9,csm6,DinG,csa3	1	5	9	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483330_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483330_1

863971-864071

Orphan

Consensus_repeat	Method
TATAATTAGACTATACCAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483330_1

>merge|NZ_LS483330|1|863971-864071|CRISPRCasFinder
TATAATTAGACTATACCAATTTTATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGGTATAATTAGACTATACCAATTAT

>NZ_LS483330|1|1|863971-864071|CRISPRCasFinder
TATAATTAGACTATACCAATTTT	ATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGG
TATAATTAGACTATACCAATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483330.1\|WP_002992407.1\|871574_872897_-\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_LS483330.1\|WP_002989605.1\|853246_853867_-\|DUF3862-domain-containing-protein	unknown	unknown	gnl\|CDD\|289729
NZ_LS483330.1\|WP_111703254.1\|873427_875746_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_LS483330.1\|WP_002984447.1\|861669_863172_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_LS483330.1\|WP_014635494.1\|867870_868707_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_LS483330.1\|WP_002984469.1\|876110_876359_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_LS483330.1\|WP_011284887.1\|850725_852990_+\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NZ_LS483330.1\|WP_111703252.1\|857403_860514_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_LS483330.1\|WP_002984437.1\|856149_856848_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LS483330.1\|WP_002989617.1\|856847_857219_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_LS483330.1\|WP_002984444.1\|860593_861607_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483330.1\|WP_111703253.1\|864122_865937_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_LS483330.1\|WP_002992417.1\|866574_867216_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_LS483330.1\|WP_002989626.1\|866132_866468_+\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_LS483330.1\|WP_002989607.1\|854607_855222_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_LS483330.1\|WP_002992415.1\|867225_867855_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LS483330.1\|WP_014635492.1\|870219_871455_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_LS483330.1\|WP_009880829.1\|869076_869850_+\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_LS483330.1\|WP_111703251.1\|855354_856140_-\|ABC-transporter-permease	unknown	unknown	unknown
NZ_LS483330.1\|WP_002984449.1\|863389_863947_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044

Protein	Function_ID	Function_description	E-value
NZ_LS483330.1\|WP_002992407.1\|871574_872897_-\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_LS483330.1\|WP_002989605.1\|853246_853867_-\|DUF3862-domain-containing-protein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	6.81674e-87
NZ_LS483330.1\|WP_111703254.1\|873427_875746_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483330.1\|WP_002984447.1\|861669_863172_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_LS483330.1\|WP_014635494.1\|867870_868707_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.58337e-109
NZ_LS483330.1\|WP_011284887.1\|850725_852990_+\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NZ_LS483330.1\|WP_111703252.1\|857403_860514_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_LS483330.1\|WP_014635492.1\|870219_871455_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	5.43501e-96
NZ_LS483330.1\|WP_002989617.1\|856847_857219_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.0536e-49
NZ_LS483330.1\|WP_002984444.1\|860593_861607_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483330.1\|WP_111703253.1\|864122_865937_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_LS483330.1\|WP_002992417.1\|866574_867216_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NZ_LS483330.1\|WP_002989626.1\|866132_866468_+\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	2.02984e-64
NZ_LS483330.1\|WP_002989607.1\|854607_855222_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NZ_LS483330.1\|WP_002992415.1\|867225_867855_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.61041e-111
NZ_LS483330.1\|WP_002984469.1\|876110_876359_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_LS483330.1\|WP_009880829.1\|869076_869850_+\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	2.06073e-97
NZ_LS483330.1\|WP_002984437.1\|856149_856848_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
NZ_LS483330.1\|WP_002984449.1\|863389_863947_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38

>NZ_LS483330.1|WP_002984449.1|863389_863947_+|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_LS483330.1|WP_002984447.1|861669_863172_+|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_LS483330.1|WP_002984444.1|860593_861607_+|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_LS483330.1|WP_111703252.1|857403_860514_+|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKFHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQSPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_LS483330.1|WP_002989617.1|856847_857219_-|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_LS483330.1|WP_002984437.1|856149_856848_-|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_LS483330.1|WP_111703251.1|855354_856140_-|ABC-transporter-permease
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSAGSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_LS483330.1|WP_002989607.1|854607_855222_+|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_LS483330.1|WP_002989605.1|853246_853867_-|DUF3862-domain-containing-protein
MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQFDQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYSQASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE
>NZ_LS483330.1|WP_011284887.1|850725_852990_+|glycogen/starch/alpha-glucan-family-phosphorylase
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDISYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFNNKLALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
>NZ_LS483330.1|WP_111703253.1|864122_865937_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLAITRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_LS483330.1|WP_002989626.1|866132_866468_+|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NZ_LS483330.1|WP_002992417.1|866574_867216_+|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_LS483330.1|WP_002992415.1|867225_867855_+|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_LS483330.1|WP_014635494.1|867870_868707_+|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKDRQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NZ_LS483330.1|WP_009880829.1|869076_869850_+|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NZ_LS483330.1|WP_014635492.1|870219_871455_-|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVSVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQITPIAKKQLHHTHYRIVKM
>NZ_LS483330.1|WP_002992407.1|871574_872897_-|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFVLMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_LS483330.1|WP_111703254.1|873427_875746_+|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMVTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSAFQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTEIHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_LS483330.1|WP_002984469.1|876110_876359_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN

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Crispr_ID: NZ_LS483330_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483330_2

1063504-1063869

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	PILER-CR

5 spacers

csn2,cas2,cas9

The CRISPR arrays of NZ_LS483330_2

>merge|NZ_LS483330|2|1063504-1063869|CRISPRCasFinder,CRT,PILER-CR
TAATGGAGACCACTCAAAACAGCATAGCTATAAAACCATTCGGCAACACATAATCAAAAATCTGTCGTTTTGGGACCATCCAAAACAACATAGCTCTAAAACACGAATCACCAAAATCAGTCCTCTTCATCTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACCGTTAGCAGTCAGTTTGTTAAAAAAAGCATGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTGATTGGAAAACGGTGAGGGTAGCGCATTGGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTAGTACGTAAAGATGGCACACATACTGCCTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483330|2|2|1063504-1063869|CRISPRCasFinder
TAATGGAGACCACTCAAAACAGCATAGCTATAAAAC	CATTCGGCAACACATAATCAAAAATCTGTC
GTTTTGGGACCATCCAAAACAACATAGCTCTAAAAC	ACGAATCACCAAAATCAGTCCTCTTCATCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CGTTAGCAGTCAGTTTGTTAAAAAAAGCAT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGATTGGAAAACGGTGAGGGTAGCGCATTG
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TAGTACGTAAAGATGGCACACATACTGCCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483330|2|1|1063504-1063869|CRT
TAATGGAGACCACTCAAAACAGCATAGCTATAAAAC	CATTCGGCAACACATAATCAAAAATCTGTC
GTTTTGGGACCATCCAAAACAACATAGCTCTAAAAC	ACGAATCACCAAAATCAGTCCTCTTCATCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CGTTAGCAGTCAGTTTGTTAAAAAAAGCAT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGATTGGAAAACGGTGAGGGTAGCGCATTG
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TAGTACGTAAAGATGGCACACATACTGCCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483330|2|1|1063570-1063869|PILER-CR
GTTTTGGGACCATCCAAAACAACATAGCTCTAAAAC	ACGAATCACCAAAATCAGTCCTCTTCATCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CGTTAGCAGTCAGTTTGTTAAAAAAAGCAT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGATTGGAAAACGGTGAGGGTAGCGCATTG
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TAGTACGTAAAGATGGCACACATACTGCCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483330.1\|WP_111703746.1\|1063324_1063483_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|173387
NZ_LS483330.1\|WP_111703312.1\|1063971_1064634_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_LS483330.1\|WP_111703313.1\|1065830_1069937_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_LS483330.1\|WP_011888915.1\|1073765_1074407_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483330.1\|WP_002989967.1\|1075939_1076896_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NZ_LS483330.1\|WP_168391421.1\|1059855_1060956_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_LS483330.1\|WP_004218782.1\|1072572_1073703_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483330.1\|WP_014407546.1\|1059231_1059669_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483330.1\|WP_111703311.1\|1058082_1059102_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483330.1\|WP_063812273.1\|1074530_1075886_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483330.1\|WP_002989934.1\|1056940_1057432_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483330.1\|WP_002989943.1\|1061422_1063255_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483330.1\|WP_010922249.1\|1071046_1071811_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483330.1\|WP_011106805.1\|1064623_1064965_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_LS483330.1\|WP_111703310.1\|1056114_1056924_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483330.1\|WP_076634216.1\|1057450_1057876_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483330.1\|WP_111703315.1\|1071810_1072563_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483330.1\|WP_111703314.1\|1070414_1071047_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483330.1\|WP_002989931.1\|1055290_1056118_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483330.1\|WP_111703309.1\|1053505_1055155_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519

Protein	Function_ID	Function_description	E-value
NZ_LS483330.1\|WP_111703746.1\|1063324_1063483_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|173387	PTZ00093, PTZ00093, nucleoside diphosphate kinase, cytosolic; Provisional.	2.54416e-06
NZ_LS483330.1\|WP_111703312.1\|1063971_1064634_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	8.93607e-121
NZ_LS483330.1\|WP_111703313.1\|1065830_1069937_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LS483330.1\|WP_002989967.1\|1075939_1076896_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.23494e-114
NZ_LS483330.1\|WP_168391421.1\|1059855_1060956_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	6.64853e-11
NZ_LS483330.1\|WP_004218782.1\|1072572_1073703_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483330.1\|WP_014407546.1\|1059231_1059669_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	7.26176e-84
NZ_LS483330.1\|WP_111703311.1\|1058082_1059102_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	4.42508e-103
NZ_LS483330.1\|WP_063812273.1\|1074530_1075886_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483330.1\|WP_002989934.1\|1056940_1057432_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NZ_LS483330.1\|WP_002989943.1\|1061422_1063255_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483330.1\|WP_010922249.1\|1071046_1071811_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.29438e-128
NZ_LS483330.1\|WP_011106805.1\|1064623_1064965_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.69845e-58
NZ_LS483330.1\|WP_111703310.1\|1056114_1056924_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	3.20225e-76
NZ_LS483330.1\|WP_076634216.1\|1057450_1057876_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	9.79007e-31
NZ_LS483330.1\|WP_111703315.1\|1071810_1072563_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.98519e-109
NZ_LS483330.1\|WP_111703314.1\|1070414_1071047_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.76894e-86
NZ_LS483330.1\|WP_002989931.1\|1055290_1056118_-\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483330.1\|WP_111703309.1\|1053505_1055155_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	5.43632e-77

>NZ_LS483330.1|WP_111703746.1|1063324_1063483_-|nucleoside-diphosphate-kinase
MRGNFAQALGDDGGIFNMVHGSHSKDSARREIVLWSHQSNLGSSAILLQDNP
>NZ_LS483330.1|WP_002989943.1|1061422_1063255_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK
>NZ_LS483330.1|WP_168391421.1|1059855_1060956_-|LPXTG-cell-wall-anchor-domain-containing-protein
MTKLLTYLQEREQAENNWRTRLLRGMQEHVLDGQDGRDGAKGDQGPRGPVGPAGQAGKDGIPGATGPRGPVGPQGPVGPAGQAGKDGTPGATGPQGPRGEKGDPGEKGADGAPGAKGDQGPRGPVGPAGQAGKDGTPGATGPQGPRGEKGDPGEKGADGAPGAKGDRGETGPVGPRGDKGETGDKGEPGPAGKDGDRGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGQDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>NZ_LS483330.1|WP_014407546.1|1059231_1059669_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET
>NZ_LS483330.1|WP_111703311.1|1058082_1059102_-|YeiH-family-putative-sulfate-export-transporter
MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLLALFYEHRDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEEGFSLRKSFPRFILFFLLASLITTLMTSLGVSADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483330.1|WP_076634216.1|1057450_1057876_-|PTS-sugar-transporter-subunit-IIA
MERKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483330.1|WP_002989934.1|1056940_1057432_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483330.1|WP_111703310.1|1056114_1056924_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMIHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAINKQKTFDSKESEEEDFFA
>NZ_LS483330.1|WP_002989931.1|1055290_1056118_-|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483330.1|WP_111703309.1|1053505_1055155_-|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKKLSTADLSKHYFHLRHSSQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483330.1|WP_111703312.1|1063971_1064634_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLDEPIPLRGGTILVLEDVCVFSKIVQHCYQYEEDSELKFFDHKMKAIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKFLGVKVETQSDAIFEKCLEILQIFKYLTKKKLVVFVNSGAFLTKEEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>NZ_LS483330.1|WP_011106805.1|1064623_1064965_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPHKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NZ_LS483330.1|WP_111703313.1|1065830_1069937_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWSVITDDYKVPSKKMKVFGNTGKQTIKKNLLGVILFDSGETAEATRLKRTARRRYTRRKNRIRYLQEIFSSEMSKVDDSFFHRLEESFLVEEDKNHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPYQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKKYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSDILKEYPVENTQLQNEKLYLYYLQNGRDMYVDRELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKRKNYWKQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVRVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKAKKLKPVKELVGITIMERSSFEKDPIDFLEAKGYKEVRKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGAPAAFKYFDTTIGRNRYKSIKEVLDATLIHQSITGLYETRIDLSQLGGD
>NZ_LS483330.1|WP_111703314.1|1070414_1071047_-|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILIMIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLQTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_LS483330.1|WP_010922249.1|1071046_1071811_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFHVETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483330.1|WP_111703315.1|1071810_1072563_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEVLTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIEIKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESETD
>NZ_LS483330.1|WP_004218782.1|1072572_1073703_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483330.1|WP_011888915.1|1073765_1074407_-|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDTQNRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483330.1|WP_063812273.1|1074530_1075886_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDVEVDYYVDTIADVVRTEIGCDN
>NZ_LS483330.1|WP_002989967.1|1075939_1076896_-|YbbR-like-domain-containing-protein
MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIETYTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLTHSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEISKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASAIDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDIDEIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK

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Crispr_ID: NZ_LS483330_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483330_3

1655063-1655130

Orphan

Consensus_repeat	Method
GCTCCGGTGTCACCTTTTTCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483330_3

>merge|NZ_LS483330|3|1655063-1655130|CRISPRCasFinder
TCGCCCGTTTCACCTTTTTCACCTTGTGGGCCTACTGGACCTTGAGCTCCGGTGTCACCTTTTTCACC

>NZ_LS483330|3|3|1655063-1655130|CRISPRCasFinder
TCGCCCGTTTCACCTTTTTCACC	TTGTGGGCCTACTGGACCTTGA
GCTCCGGTGTCACCTTTTTCACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483330.1\|WP_111703606.1\|1663150_1663894_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_LS483330.1\|WP_009880696.1\|1663881_1664172_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	unknown
NZ_LS483330.1\|WP_021775361.1\|1648909_1649758_-\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306
NZ_LS483330.1\|WP_111703588.1\|1651517_1651961_-\|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl\|CDD\|235383
NZ_LS483330.1\|WP_002993686.1\|1647478_1648612_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NZ_LS483330.1\|WP_111703584.1\|1645736_1647350_-\|alpha-glucosidase	unknown	unknown	gnl\|CDD\|200472
NZ_LS483330.1\|WP_010922683.1\|1640103_1640853_-\|isoprenyl-transferase	unknown	unknown	gnl\|CDD\|184840
NZ_LS483330.1\|WP_111703600.1\|1661191_1662145_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NZ_LS483330.1\|WP_111703594.1\|1656998_1657817_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197313
NZ_LS483330.1\|WP_111703582.1\|1642041_1645539_-\|pullulanase	unknown	unknown	gnl\|CDD\|273973
NZ_LS483330.1\|WP_172449975.1\|1664226_1665578_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NZ_LS483330.1\|WP_111703592.1\|1656123_1656606_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|179443
NZ_LS483330.1\|WP_111703598.1\|1660442_1661192_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|224303
NZ_LS483330.1\|WP_111703602.1\|1662750_1662960_-\|virulence-RhuM-family-protein	unknown	unknown	gnl\|CDD\|379118
NZ_LS483330.1\|WP_111703581.1\|1641552_1641927_-\|thioredoxin	unknown	unknown	gnl\|CDD\|273542
NZ_LS483330.1\|WP_023611836.1\|1662215_1662686_-\|DUF3013-family-protein	unknown	unknown	gnl\|CDD\|337951
NZ_LS483330.1\|WP_030126241.1\|1651975_1654195_-\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|223394
NZ_LS483330.1\|WP_111703596.1\|1657899_1660086_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|131058
NZ_LS483330.1\|WP_111703586.1\|1650097_1651420_+\|streptokinase	unknown	unknown	gnl\|CDD\|367201
NZ_LS483330.1\|WP_002988027.1\|1641071_1641437_-\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|235822

Protein	Function_ID	Function_description	E-value
NZ_LS483330.1\|WP_111703606.1\|1663150_1663894_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.13234e-44
NZ_LS483330.1\|WP_021775361.1\|1648909_1649758_-\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	4.77915e-53
NZ_LS483330.1\|WP_111703588.1\|1651517_1651961_-\|D-tyrosyl-tRNA(Tyr)-deacylase	gnl\|CDD\|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	6.17452e-95
NZ_LS483330.1\|WP_002993686.1\|1647478_1648612_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NZ_LS483330.1\|WP_111703584.1\|1645736_1647350_-\|alpha-glucosidase	gnl\|CDD\|200472	cd11333, AmyAc_SI_OligoGlu_DGase, Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins. The sucrose isomerases (SIs) Isomaltulose synthase (EC 5.4.99.11) and Trehalose synthase (EC 5.4.99.16) catalyze the isomerization of sucrose and maltose to produce isomaltulose and trehalulose, respectively. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Dextran glucosidase (DGase, EC 3.2.1.70) hydrolyzes alpha-1,6-glucosidic linkages at the non-reducing end of panose, isomaltooligosaccharides and dextran to produce alpha-glucose.The common reaction chemistry of the alpha-amylase family enzymes is based on a two-step acid catalytic mechanism that requires two critical carboxylates: one acting as a general acid/base (Glu) and the other as a nucleophile (Asp). Both hydrolysis and transglycosylation proceed via the nucleophilic substitution reaction between the anomeric carbon, C1 and a nucleophile. Both enzymes contain the three catalytic residues (Asp, Glu and Asp) common to the alpha-amylase family as well as two histidine residues which are predicted to be critical to binding the glucose residue adjacent to the scissile bond in the substrates. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NZ_LS483330.1\|WP_010922683.1\|1640103_1640853_-\|isoprenyl-transferase	gnl\|CDD\|184840	PRK14830, PRK14830, undecaprenyl pyrophosphate synthase; Provisional.	6.79118e-177
NZ_LS483330.1\|WP_111703600.1\|1661191_1662145_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	3.42725e-145
NZ_LS483330.1\|WP_111703594.1\|1656998_1657817_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197313	cd09079, RgfB-like, Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins. This family includes Streptococcus agalactiae RgfB (for regulator of fibrinogen binding) and related proteins. The function of RgfB is unknown. It is part of a putative two component signal transduction system designated rgfBDAC (the rgf locus was identified in a screen for mutants of Streptococcus agalactiae with altered binding to fibrinogen). RgfA,-C,and -D do not belong to this superfamily: rgfA encodes a putative response regulator, and rgfC, a putative histidine kinase. All four genes are co-transcribed, and may be involved in regulating expression of bacterial cell surface components. This family belongs to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds.	4.5784e-98
NZ_LS483330.1\|WP_111703582.1\|1642041_1645539_-\|pullulanase	gnl\|CDD\|273973	TIGR02102, alkaline_amylopullulanase, pullulanase, extracellular, Gram-positive. Pullulan is an unusual, industrially important polysaccharide in which short alpha-1,4 chains (maltotriose) are connected in alpha-1,6 linkages. Enzymes that cleave alpha-1,6 linkages in pullulan and release maltotriose are called pullulanases although pullulan itself may not be the natural substrate. In contrast, a glycogen debranching enzyme such GlgX, homologous to this family, can release glucose at alpha,1-6 linkages from glycogen first subjected to limit degradation by phosphorylase. Characterized members of this family include a surface-located pullulanase from Streptococcus pneumoniae () and an extracellular bifunctional amylase/pullulanase with C-terminal pullulanase activity (.	0
NZ_LS483330.1\|WP_172449975.1\|1664226_1665578_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.7644e-47
NZ_LS483330.1\|WP_111703592.1\|1656123_1656606_+\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|179443	PRK02551, PRK02551, flavoprotein NrdI; Provisional.	7.54865e-94
NZ_LS483330.1\|WP_111703598.1\|1660442_1661192_-\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	3.71527e-83
NZ_LS483330.1\|WP_111703602.1\|1662750_1662960_-\|virulence-RhuM-family-protein	gnl\|CDD\|379118	pfam13310, Virulence_RhuM, Virulence protein RhuM family. There are currently no experimental data for members of this group or their homologs. However, these proteins are implicated in virulence/pathogenicity because RhuM is encoded in the SPI-3 pathogenicity island in Salmonella typhimurium.	9.70171e-10
NZ_LS483330.1\|WP_111703581.1\|1641552_1641927_-\|thioredoxin	gnl\|CDD\|273542	TIGR01295, Pediocin_PA-1_biosynthesis_protein_PedC, bacteriocin transport accessory protein, putative. This model describes a small family of proteins believed to aid in the export of various class II bacteriocins, which are ribosomally-synthesized, non-lantibiotic bacterial peptide antibiotics. Members of this family are found in operons for pediocin PA-1 from Pediococcus acidilactici and brochocin-C from Brochothrix campestris.	3.70001e-15
NZ_LS483330.1\|WP_023611836.1\|1662215_1662686_-\|DUF3013-family-protein	gnl\|CDD\|337951	pfam11217, DUF3013, Protein of unknown function (DUF3013). This bacterial family of proteins with unknown function appear to be restricted to Firmicutes.	2.87338e-64
NZ_LS483330.1\|WP_030126241.1\|1651975_1654195_-\|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl\|CDD\|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NZ_LS483330.1\|WP_111703596.1\|1657899_1660086_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|131058	TIGR02003, PTS_system_glucose-specific_IIBC_component, PTS system, IIBC component. This model represents a family of fused B and C components of PTS enzyme II. This clade is a member of a larger family which contains enzyme II's specific for a variety of sugars including glucose (TIGR02002) and N-acetylglucosamine (TIGR01998). None of the members of this clade have been experimentally characterized. This clade includes sequences from Streptococcus and Enterococcus which also include a C-terminal A domain as well as Bacillus and Clostridium which do not. In nearly all cases, these species also contain an authentic glucose-specific PTS transporter. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_LS483330.1\|WP_111703586.1\|1650097_1651420_+\|streptokinase	gnl\|CDD\|367201	pfam02821, Staphylokinase, Staphylokinase/Streptokinase family.	3.52765e-19
NZ_LS483330.1\|WP_002988027.1\|1641071_1641437_-\|preprotein-translocase-subunit-YajC	gnl\|CDD\|235822	PRK06531, yajC, preprotein translocase subunit YajC; Validated.	4.20228e-61

>NZ_LS483330.1|WP_030126241.1|1651975_1654195_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVRKSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIVDGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALVEAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQSDVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKEMHQVAEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFSERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVVEIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYVANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKAEAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKGRGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQILSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG
>NZ_LS483330.1|WP_111703588.1|1651517_1651961_-|D-tyrosyl-tRNA(Tyr)-deacylase
MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAYAVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLARQLYDSFNEQLAEFVPVERGVFGADMQVSLVNDGPVTIILDTKCH
>NZ_LS483330.1|WP_111703586.1|1650097_1651420_+|streptokinase
MKNYLSFGMFALLFALTFGTVKPVQAIAGYEWLLDRPSVNNSQLVVSVAGTVEGTNQEISLKFFEIDLTSRPAHGGKTEQGLSPKSKPFATDKGAMPHKLEKADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDDSVTLPTQPVQEFLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKERYHLTTLAVGDSLSSQELAAIAQFILSKEHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYGVNKKSGQNEKINNTDLISEKYYVLKKGEEPYDPFDRSHLKLFTINYVDVDTNKLLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGNVEDNHDDTNRIITVYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK
>NZ_LS483330.1|WP_021775361.1|1648909_1649758_-|PucR-family-transcriptional-regulator
MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKERLLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQQMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQVAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLSPQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAHLFLLKY
>NZ_LS483330.1|WP_002993686.1|1647478_1648612_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGKSTTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGLKLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMDEPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGNGTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEGQAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVKLGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR
>NZ_LS483330.1|WP_111703584.1|1645736_1647350_-|alpha-glucosidase
MKKHWWHKATIYQIYPRSFKDTNGNGIGDLKGITSQLDYLQKLGITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVNHTSDEHAWFVEARENPNSSERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSKRQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYLKEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKWDYAKELDVPALKTIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKALAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDSIRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQNINVADALADPDSIFYTYQKLIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLAGAQVIITNTDVDTVLETKHLQPWDAFCLKLKA
>NZ_LS483330.1|WP_111703582.1|1642041_1645539_-|pullulanase
MKKKVNQGSKRYQYLLKKWGIGFVIATTGTVMLGCTPSILTHQVAAKTIVGLARDEAPQGDGNAKSGDGFQSSSKEAKPVLDSSSANPASIAEHHLRMHFKTLPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSYLINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDNLAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIKVQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDGLDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVARQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTKVLGQADLTKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATATDDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHPFGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQHYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPNYYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAAAIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKVIAADQDWMKATNTVGVFSDDIRNTLKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDVIAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNSDYKTKVSDDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGLIALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNADNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDSLTALVLKVSSKPADPSSQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLAAGVALLLLAISLLMKRPKD
>NZ_LS483330.1|WP_111703581.1|1641552_1641927_-|thioredoxin
MRPKEKETSMTFEEIVANFIPSSVAEVASAIASGKDMIVFLGRSSCPYCRRFAPKLAQVATDNQKDVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQHQRAVCDSSLTPDDILAFLTRE
>NZ_LS483330.1|WP_002988027.1|1641071_1641437_-|preprotein-translocase-subunit-YajC
MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVVTIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVNEPAVETVDSTDTDSAIESH
>NZ_LS483330.1|WP_010922683.1|1640103_1640853_-|isoprenyl-transferase
MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHENNVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQDVLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTPVLWPDFKKAELLKAIADYNRRQRRFGKV
>NZ_LS483330.1|WP_111703592.1|1656123_1656606_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKHETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKNFNHQYCLTAKQYAKRFDFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
>NZ_LS483330.1|WP_111703594.1|1656998_1657817_-|endonuclease/exonuclease/phosphatase-family-protein
MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQLIESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEGVAILSKQPIHVSDILVSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLGEWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIVADIDGWEDNKEAFKVDHVFTSKDFVIKASHITFEGGDAPVVSDHYGLEVTLDWR
>NZ_LS483330.1|WP_111703596.1|1657899_1660086_-|PTS-transporter-subunit-EIIC
MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMINHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRITGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGATAYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIASSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQDPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVDADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNLRVHSFGNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGRLGNYDADILGDRNTQARPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDPAKVGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLTSKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVAGLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVADLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAKTKVATVEL
>NZ_LS483330.1|WP_111703598.1|1660442_1661192_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLADKAEVVLVFDDGVKYLAKVTNSMAHELEIIEALPDQVELPVEVTIASGFPKGDKLDTIAQKVTELGASALWGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEQKAEFLKSLSSFDHIFIAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAASAIKVGLGPRIMRAETAPLYALSALSYALELQASK
>NZ_LS483330.1|WP_111703600.1|1661191_1662145_-|50S-ribosomal-protein-L11-methyltransferase
METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSSDYIGQKDRFGELYPDVEQSDMIAIIAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQELAEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKMSLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQGTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEKLDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG
>NZ_LS483330.1|WP_023611836.1|1662215_1662686_-|DUF3013-family-protein
MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNKEAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFEAADYLVTIPFDAKKGFSREFLAYFAQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEAASYPYPRY
>NZ_LS483330.1|WP_111703602.1|1662750_1662960_-|virulence-RhuM-family-protein
MEGLIERRHSFIKEHFVASIDNFLNFREYRMIEGKGSISMKFAKEKASREYVEFNKLQKINPDKGHKKI
>NZ_LS483330.1|WP_111703606.1|1663150_1663894_-|IS3-family-transposase
MDKVSLIKLVEDYKNNYPIVFILDCFKVKRSTYYRWKKEYEKPQKKDDVIELIEQLCMENHFIYGYRTITRLLKKIHGLTVNTKKVYRIMKNNGWLCRTRTKKVPNLGKAYYLTDNKLSRDFHADKPIEKLVTDITYLYFGNCKLYLSSIMDLYNREIIAYTISDCQDTDFVLDTLNQLKLPKGAILHSDQGSVYTSMAYYQACTEKGIIRSMSRKGTPADNACIEWFHSVLKTETFYLHNRRKYNS
>NZ_LS483330.1|WP_009880696.1|1663881_1664172_-|helix-turn-helix-domain-containing-protein
MVKKAYSWETKLACIEMKKAGKSNRVIMETLGIKNNSQIYTWMKWYENEELYRFHQCVGKQYTYGKGLEHLSEVEQLQLQVDLLKKYRGLIRKSIK
>NZ_LS483330.1|WP_172449975.1|1664226_1665578_-|IS3-family-transposase
MKFNQETQETKVKIYELRQMGEYIKSISKKFDMAESDLKYMIRLIDRYGVTIVQKCKNHYYSLELKQEIINKVLIDGQSQKQTSLDYALPTSSMLSRWIAQYKKNGYTILEKPRGGPSKMGRKRKKNLKEMTEVERLQKELEYLRAENAVLKKPERIPLEGRSKAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADNLIKRHFEGSKPYEKCYTDVTELALPEGKLYLSPVLDGYNSEIIDFTLSRSPNLKQVQTMLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILASMSRKGNSPDNGMMESFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NZ_LS483330.1	737023-737052	1	0.967

1. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to position: 737023-737052, mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaaaacataatcaaaaatctgtc	Protospacer
********** *******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448767	Streptococcus phage Javan467, complete genome	34025-34054	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448769	Streptococcus phage Javan471, complete genome	35895-35924	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	34130-34159	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448681	Streptococcus phage Javan141, complete genome	40267-40296	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448943	Streptococcus phage Javan450, complete genome	34025-34054	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448684	Streptococcus phage Javan151, complete genome	35895-35924	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448786	Streptococcus phage Javan509, complete genome	34025-34054	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448962	Streptococcus phage Javan496, complete genome	32778-32807	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448963	Streptococcus phage Javan498, complete genome	31525-31554	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448845	Streptococcus phage Javan118, complete genome	37301-37330	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448856	Streptococcus phage Javan158, complete genome	19346-19375	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448673	Streptococcus phage Javan119, complete genome	46753-46782	0	1.0
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MH853357	Streptococcus phage LF3, partial genome	27327-27356	0	1.0
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	KY363359	Streptococcus phage Str03, complete genome	27812-27841	0	1.0
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448863	Streptococcus phage Javan18, complete genome	8130-8159	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448871	Streptococcus phage Javan196, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448767	Streptococcus phage Javan467, complete genome	29555-29584	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	29660-29689	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448779	Streptococcus phage Javan497, complete genome	33951-33980	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448943	Streptococcus phage Javan450, complete genome	29555-29584	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448697	Streptococcus phage Javan185, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448959	Streptococcus phage Javan488, complete genome	35557-35586	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448693	Streptococcus phage Javan177, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448786	Streptococcus phage Javan509, complete genome	29555-29584	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448941	Streptococcus phage Javan446, complete genome	36940-36969	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448696	Streptococcus phage Javan183, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448962	Streptococcus phage Javan496, complete genome	25351-25380	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448963	Streptococcus phage Javan498, complete genome	25177-25206	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448773	Streptococcus phage Javan485, complete genome	30684-30713	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448951	Streptococcus phage Javan470, complete genome	34485-34514	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448868	Streptococcus phage Javan188, complete genome	35276-35305	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448866	Streptococcus phage Javan184, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448950	Streptococcus phage Javan464, complete genome	34740-34769	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448699	Streptococcus phage Javan189, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448867	Streptococcus phage Javan186, complete genome	35275-35304	0	1.0
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448675	Streptococcus phage Javan129, complete genome	42204-42233	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448685	Streptococcus phage Javan155, complete genome	36137-36166	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448942	Streptococcus phage Javan448, complete genome	25827-25856	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK449010	Streptococcus phage Javan90, complete genome	36929-36958	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448952	Streptococcus phage Javan472, complete genome	40057-40086	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448779	Streptococcus phage Javan497, complete genome	39526-39555	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_004585	Streptococcus prophage 315.2, complete genome	40796-40825	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448848	Streptococcus phage Javan126, complete genome	37045-37074	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448857	Streptococcus phage Javan164, complete genome	37045-37074	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448966	Streptococcus phage Javan508, complete genome	40651-40680	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448763	Streptococcus phage Javan451, complete genome	33692-33721	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448677	Streptococcus phage Javan133, complete genome	38045-38074	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_009018	Streptococcus phage phi3396, complete genome	38341-38370	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448968	Streptococcus phage Javan512, complete genome	39634-39663	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448945	Streptococcus phage Javan454, complete genome	39038-39067	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448772	Streptococcus phage Javan483, complete genome	40894-40923	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448941	Streptococcus phage Javan446, complete genome	45045-45074	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448797	Streptococcus phage Javan531, complete genome	39634-39663	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448793	Streptococcus phage Javan523, complete genome	41430-41459	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448783	Streptococcus phage Javan503, complete genome	37500-37529	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448978	Streptococcus phage Javan532, complete genome	39481-39510	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448676	Streptococcus phage Javan131, complete genome	44776-44805	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448950	Streptococcus phage Javan464, complete genome	42136-42165	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448833	Streptococcus phage Javan87, complete genome	38493-38522	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448957	Streptococcus phage Javan484, complete genome	46655-46684	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448853	Streptococcus phage Javan144, complete genome	36137-36166	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_004589	Streptococcus prophage 315.6, complete genome	39731-39760	1	0.967
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448969	Streptococcus phage Javan514, complete genome	27798-27827	1	0.967
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448972	Streptococcus phage Javan520, complete genome	29733-29762	1	0.967
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448774	Streptococcus phage Javan487, complete genome	27912-27941	1	0.967
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448954	Streptococcus phage Javan476, complete genome	34133-34162	1	0.967
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448957	Streptococcus phage Javan484, complete genome	39524-39553	1	0.967
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448852	Streptococcus phage Javan140, complete genome	40905-40934	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448771	Streptococcus phage Javan481, complete genome	34902-34931	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448858	Streptococcus phage Javan166, complete genome	45135-45164	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448860	Streptococcus phage Javan172, complete genome	39769-39798	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448969	Streptococcus phage Javan514, complete genome	33023-33052	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448964	Streptococcus phage Javan502, complete genome	35202-35231	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448972	Streptococcus phage Javan520, complete genome	34957-34986	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448774	Streptococcus phage Javan487, complete genome	33136-33165	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448773	Streptococcus phage Javan485, complete genome	35908-35937	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_009819	Streptococcus phage P9, complete genome	40402-40431	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448854	Streptococcus phage Javan146, complete genome	45021-45050	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448694	Streptococcus phage Javan179, complete genome	41383-41412	2	0.933
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448769	Streptococcus phage Javan471, complete genome	6774-6803	2	0.933
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448684	Streptococcus phage Javan151, complete genome	6774-6803	2	0.933
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448682	Streptococcus phage Javan143, complete genome	8142-8171	2	0.933
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448888	Streptococcus phage Javan26, complete genome	7973-8002	2	0.933
NZ_LS483330_2	2.2\|1063606\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063606-1063635	30	MK448764	Streptococcus phage Javan457, complete genome	6534-6563	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448791	Streptococcus phage Javan517, complete genome	13214-13243	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	NC_004587	Streptococcus prophage 315.4, complete genome	13309-13338	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	14579-14608	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448977	Streptococcus phage Javan530, complete genome	13214-13243	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448788	Streptococcus phage Javan511, complete genome	13214-13243	2	0.933
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448950	Streptococcus phage Javan464, complete genome	14920-14949	2	0.933
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448862	Streptococcus phage Javan178, complete genome	32631-32660	2	0.933
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448952	Streptococcus phage Javan472, complete genome	34690-34719	2	0.933
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448694	Streptococcus phage Javan179, complete genome	35205-35234	2	0.933
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448970	Streptococcus phage Javan516, complete genome	45854-45883	3	0.9
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448865	Streptococcus phage Javan182, complete genome	33704-33733	3	0.9
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448690	Streptococcus phage Javan169, complete genome	44056-44085	3	0.9
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448869	Streptococcus phage Javan190, complete genome	35528-35557	3	0.9
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448870	Streptococcus phage Javan192, complete genome	35528-35557	3	0.9
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	KC348604	Streptococcus phage phiS10, complete genome	12878-12907	3	0.9
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448933	Streptococcus phage Javan420, complete genome	17265-17294	3	0.9
NZ_LS483330_2	2.5\|1063804\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063804-1063833	30	MK448777	Streptococcus phage Javan491, complete genome	29463-29492	3	0.9
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448791	Streptococcus phage Javan517, complete genome	41931-41960	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_004587	Streptococcus prophage 315.4, complete genome	41507-41536	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	42777-42806	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448977	Streptococcus phage Javan530, complete genome	41412-41441	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448788	Streptococcus phage Javan511, complete genome	41412-41441	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448795	Streptococcus phage Javan527, complete genome	47193-47222	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448859	Streptococcus phage Javan170, complete genome	42662-42691	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448686	Streptococcus phage Javan157, complete genome	40163-40192	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448850	Streptococcus phage Javan132, complete genome	42976-43005	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448951	Streptococcus phage Javan470, complete genome	38688-38717	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448688	Streptococcus phage Javan161, complete genome	42620-42649	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448678	Streptococcus phage Javan135, complete genome	39400-39429	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448781	Streptococcus phage Javan5, complete genome	40285-40314	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448749	Streptococcus phage Javan39, complete genome	43336-43365	4	0.867
NZ_LS483330_2	2.4\|1063738\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063738-1063767	30	MK448993	Streptococcus phage Javan616, complete genome	14291-14320	4	0.867
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448862	Streptococcus phage Javan178, complete genome	39539-39568	5	0.833
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448864	Streptococcus phage Javan180, complete genome	30679-30708	5	0.833
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448683	Streptococcus phage Javan149, complete genome	41657-41686	5	0.833
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_004584	Streptococcus prophage 315.1, complete genome	39350-39379	5	0.833
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448785	Streptococcus phage Javan507, complete genome	39245-39274	5	0.833
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	U40453	Streptococcus pyogenes phage T12 repressor, excisionase (xis), integrase (int) and erythrogenic toxin A precursor (speA) genes, complete cds	3263-3292	6	0.8
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	NC_028700	Streptococcus phage T12, complete genome	37727-37756	6	0.8
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	MK448679	Streptococcus phage Javan137, complete genome	37235-37264	6	0.8
NZ_LS483330_2	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	KU873925	Pseudomonas phage pf16, complete genome	16432-16461	8	0.733
NZ_LS483330_2	2.3\|1063672\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063672-1063701	30	KC348601	Streptococcus phage phi7917, complete genome	28292-28321	8	0.733
NZ_LS483330_2	2.3\|1063672\|30\|NZ_LS483330\|CRISPRCasFinder,CRT,PILER-CR	1063672-1063701	30	MK448988	Streptococcus phage Javan578, complete genome	7499-7528	8	0.733

1. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

2. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

3. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

4. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

5. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

6. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

7. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

8. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

9. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

10. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

11. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448856 (Streptococcus phage Javan158, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

12. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 0, identity: 1.0

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatctgtc	Protospacer
******************************

13. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MH853357 (Streptococcus phage LF3, partial genome) position: , mismatch: 0, identity: 1.0

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatcagtcctcttcatct	Protospacer
******************************

14. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to KY363359 (Streptococcus phage Str03, complete genome) position: , mismatch: 0, identity: 1.0

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatcagtcctcttcatct	Protospacer
******************************

15. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448863 (Streptococcus phage Javan18, complete genome) position: , mismatch: 0, identity: 1.0

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatcagtcctcttcatct	Protospacer
******************************

16. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

17. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

18. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

19. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

20. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

21. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

22. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

23. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

24. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

25. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448941 (Streptococcus phage Javan446, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

26. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

27. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

28. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

29. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

30. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

31. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

32. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

33. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

34. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

35. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 0, identity: 1.0

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgcct	Protospacer
******************************

36. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaaaatctgtc	Protospacer
******.***********************

37. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaaaatctgtc	Protospacer
******.***********************

38. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaaaacataatcaaaaatctgtc	Protospacer
********** *******************

39. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaaaatctgtc	Protospacer
******.***********************

40. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

41. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

42. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

43. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448848 (Streptococcus phage Javan126, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

44. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448857 (Streptococcus phage Javan164, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

45. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

46. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

47. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448677 (Streptococcus phage Javan133, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

48. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaaaatccgtc	Protospacer
**************************.***

49. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

50. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

51. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

52. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448941 (Streptococcus phage Javan446, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

53. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

54. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

55. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

56. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

57. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacacataatcaaagatctgtc	Protospacer
**********************.*******

58. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

59. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaaaatctgtc	Protospacer
******.***********************

60. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatcaaaaatctgtc	Protospacer
*** **************************

61. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaaaatctgtc	Protospacer
******.***********************

62. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 1, identity: 0.967

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaacgcataatcaaaaatctgtc	Protospacer
***********.******************

63. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.967

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgctt	Protospacer
****************************.*

64. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.967

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgctt	Protospacer
****************************.*

65. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.967

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgctt	Protospacer
****************************.*

66. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.967

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tggtacgtaaagatggcacacatactgcct	Protospacer
*.****************************

67. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.967

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtaaagatggcacacatactgctt	Protospacer
****************************.*

68. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448852 (Streptococcus phage Javan140, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

69. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

70. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

71. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

72. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

73. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

74. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

75. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

76. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgtggcaacacataatcaaaaatctgtc	Protospacer
*** .*************************

77. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaatacataatcaaaaatctgtc	Protospacer
*** ******.*******************

78. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcgacaacacataatcaaagatctgtc	Protospacer
******.***************.*******

79. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.933

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
catgcggcaacacataatccaaaatctgtc	Protospacer
*** *************** **********

80. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 2, identity: 0.933

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatctgtccttttcatct	Protospacer
**************** *****.*******

81. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 2, identity: 0.933

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatctgtccttttcatct	Protospacer
**************** *****.*******

82. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 2, identity: 0.933

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatctgtccttttcatct	Protospacer
**************** *****.*******

83. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448888 (Streptococcus phage Javan26, complete genome) position: , mismatch: 2, identity: 0.933

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatctgtccttttcatct	Protospacer
**************** *****.*******

84. spacer 2.2|1063606|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 2, identity: 0.933

acgaatcaccaaaatcagtcctcttcatct	CRISPR spacer
acgaatcaccaaaatctgtccttttcatct	Protospacer
**************** *****.*******

85. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

86. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

87. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

88. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

89. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

90. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 2, identity: 0.933

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccttg	Protospacer
***************.********** ***

91. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 2, identity: 0.933

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tggtccgtaaagatggcacacatactgcct	Protospacer
*.** *************************

92. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 2, identity: 0.933

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tagtacgtagagatggcacacatactgctt	Protospacer
*********.******************.*

93. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.933

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tggtacgtaaagatggcacacacactgcct	Protospacer
*.********************.*******

94. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 3, identity: 0.9

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaaaatctgtc	Protospacer
**.. *************************

95. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448865 (Streptococcus phage Javan182, complete genome) position: , mismatch: 3, identity: 0.9

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaaaatctgtc	Protospacer
**.. *************************

96. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 3, identity: 0.9

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaaaatctgtc	Protospacer
**.. *************************

97. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448869 (Streptococcus phage Javan190, complete genome) position: , mismatch: 3, identity: 0.9

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaaaatctgtc	Protospacer
**.. *************************

98. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448870 (Streptococcus phage Javan192, complete genome) position: , mismatch: 3, identity: 0.9

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaaaatctgtc	Protospacer
**.. *************************

99. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to KC348604 (Streptococcus phage phiS10, complete genome) position: , mismatch: 3, identity: 0.9

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgccctg	Protospacer
***************.********** .**

100. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 3, identity: 0.9

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaacggtaagggtagcgctctg	Protospacer
***************.********** .**

101. spacer 2.5|1063804|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 3, identity: 0.9

tagtacgtaaagatggcacacatactgcct	CRISPR spacer
tggtacgtagagacggcacacatactgcct	Protospacer
*.*******.***.****************

102. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgccaggcaacacataatcaaaaatctgtc	Protospacer
*... *************************

103. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgccaggcaacacataatcaaaaatctgtc	Protospacer
*... *************************

104. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgccaggcaacacataatcaaaaatctgtc	Protospacer
*... *************************

105. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgccaggcaacacataatcaaaaatctgtc	Protospacer
*... *************************

106. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgccaggcaacacataatcaaaaatctgtc	Protospacer
*... *************************

107. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccgggcaaaacataatcaaaaatctgtc	Protospacer
**.. ***** *******************

108. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaagatctgtc	Protospacer
**.. *****************.*******

109. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggtaacacataatcaaaaatctgtc	Protospacer
**.. **.**********************

110. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaagatctgtc	Protospacer
**.. *****************.*******

111. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggtaacacataatcaaaaatctgtc	Protospacer
**.. **.**********************

112. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcaacacataatcaaagatctgtc	Protospacer
**.. *****************.*******

113. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448678 (Streptococcus phage Javan135, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggtaacacataatcaaaaatctgtc	Protospacer
**.. **.**********************

114. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgtgcggcaacacataatcaaatatctttc	Protospacer
*.* ****************** **** **

115. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 4, identity: 0.867

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgtgcggcaacacataatcaaatatctttc	Protospacer
*.* ****************** **** **

116. spacer 2.4|1063738|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448993 (Streptococcus phage Javan616, complete genome) position: , mismatch: 4, identity: 0.867

tgattggaaaacggtgagggtagcgcattg	CRISPR spacer
tgattggaaaatggcgagggtagcgccctg	Protospacer
***********.**.*********** .**

117. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 5, identity: 0.833

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cccctggcaacacataatcaaatatctgtc	Protospacer
* ...***************** *******

118. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 5, identity: 0.833

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cccctggcaacacataatcaaatatctgtc	Protospacer
* ...***************** *******

119. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 5, identity: 0.833

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
caccaggcgacacataatcaaagatctgtc	Protospacer
**.. ***.*************.*******

120. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 5, identity: 0.833

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgtgcggcaacacataatcaaatatcaatc	Protospacer
*.* ****************** *** .**

121. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 5, identity: 0.833

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cgtgcggcaacacataatcaaatatcaatc	Protospacer
*.* ****************** *** .**

122. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to U40453 (Streptococcus pyogenes phage T12 repressor, excisionase (xis), integrase (int) and erythrogenic toxin A precursor (speA) genes, complete cds) position: , mismatch: 6, identity: 0.8

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
attgcggcaacacataatcaaaaatcttgt	Protospacer
  * ***********************  .

123. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 6, identity: 0.8

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
attgcggcaacacataatcaaaaatcttgt	Protospacer
  * ***********************  .

124. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 6, identity: 0.8

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
ctcctggcaagacataatcaaaaatttgtc	Protospacer
* ...***** **************.****

125. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to KU873925 (Pseudomonas phage pf16, complete genome) position: , mismatch: 8, identity: 0.733

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
ctgaacgcaacaaataatcaaaaatatgtg	Protospacer
*     ****** ************ ***

126. spacer 2.3|1063672|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to KC348601 (Streptococcus phage phi7917, complete genome) position: , mismatch: 8, identity: 0.733

cgttagcagtcagtttgttaaaaaaagcat	CRISPR spacer
agttagcagacagtttgttaacaagcattt	Protospacer
 ******** *********** **. .. *

127. spacer 2.3|1063672|30|NZ_LS483330|CRISPRCasFinder,CRT,PILER-CR matches to MK448988 (Streptococcus phage Javan578, complete genome) position: , mismatch: 8, identity: 0.733

cgttagcagtcagtttgttaaaaaaagcat	CRISPR spacer
agttagcagacagtttgttaacaagcattt	Protospacer
 ******** *********** **. .. *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

30610 : 42924

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111703081.1\|30610_34336_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	8.7e-39	26.7
WP_009880323.1\|34496_35951_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_111703082.1\|35978_37001_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	1.4e-63	41.7
WP_002986700.1\|37168_37723_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_111703083.1\|37906_39454_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	5.7e-45	52.4
WP_002987712.1\|39512_40637_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_111703084.1\|40889_42155_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002986689.1\|42432_42924_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.9e-18	42.3

DBSCAN-SWA_2

331963 : 378015

Streptococcus_phage(81.63%)

holin,integrase,capsid,head,terminase,tail,portal

attL 334867:334884|attR 373446:373463

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111703139.1\|331963_332455_+	single-stranded DNA-binding protein	A0A286QNX2	Streptococcus_phage	1.7e-59	74.8
WP_002983142.1\|332619_332859_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_111703140.1\|332989_333643_-	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_002983147.1\|333775_334720_-	magnesium transporter CorA family protein	NA	NA	NA	NA
334867:334884	attL	NA	NA	NA	NA
WP_047149517.1\|334963_336061_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	1.7e-197	94.8
WP_047149516.1\|336236_336788_-	hypothetical protein	A7J267	Streptococcus_phage	9.0e-86	92.3
WP_047149515.1\|336798_337182_-	phage protein	A7J268	Streptococcus_phage	1.5e-68	98.4
WP_011184049.1\|337195_337546_-	helix-turn-helix transcriptional regulator	M1I9X0	Streptococcus_phage	1.2e-48	85.3
WP_001283052.1\|338186_338378_+	hypothetical protein	A7J270	Streptococcus_phage	7.3e-27	100.0
WP_047149514.1\|338398_338629_+	hypothetical protein	A7J271	Streptococcus_phage	6.5e-30	89.3
WP_047149513.1\|338716_338974_+	hypothetical protein	NA	NA	NA	NA
WP_023611037.1\|339002_339173_+	hypothetical protein	A7J273	Streptococcus_phage	2.9e-19	87.5
WP_047149512.1\|339165_339369_+	hypothetical protein	NA	NA	NA	NA
WP_047149511.1\|339365_339752_+	hypothetical protein	A7J274	Streptococcus_phage	4.0e-56	86.6
WP_030127426.1\|339897_340101_+	hypothetical protein	A7J276	Streptococcus_phage	3.7e-29	89.6
WP_030127427.1\|340188_340488_+	hypothetical protein	A7J277	Streptococcus_phage	3.7e-41	96.0
WP_011888943.1\|340487_341645_+	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_086934854.1\|341653_342217_+	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_047149510.1\|342259_344182_+	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	99.1
WP_111689469.1\|344186_346571_+	DNA primase	A7J282	Streptococcus_phage	3.1e-276	94.4
WP_011054885.1\|346956_347232_+	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	2.9e-45	96.7
WP_047149508.1\|347228_348551_+	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	1.1e-249	96.8
WP_011054883.1\|348551_348722_+	hypothetical protein	A7J285	Streptococcus_phage	3.1e-21	94.2
WP_011054882.1\|348714_348987_+	hypothetical protein	A7J287	Streptococcus_phage	5.7e-25	73.3
WP_011054881.1\|349119_349536_+	transcriptional regulator	A7J289	Streptococcus_phage	3.3e-72	99.3
WP_011106637.1\|349625_350078_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	6.9e-76	100.0
WP_011054879.1\|350067_351345_+\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	1.1e-246	100.0
WP_038433243.1\|351360_352893_+\|portal	phage portal protein	A7J292	Streptococcus_phage	4.5e-292	99.8
WP_032465703.1\|352852_354301_+\|capsid	minor capsid protein	A7J293	Streptococcus_phage	1.2e-278	99.8
WP_011054876.1\|354328_354517_+	hypothetical protein	A7J294	Streptococcus_phage	7.4e-24	100.0
WP_011888934.1\|354521_354788_+	hypothetical protein	Q938K9	Temperate_phage	2.9e-37	96.6
WP_011888933.1\|354949_355519_+	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.9e-83	100.0
WP_002983429.1\|355531_356419_+	hypothetical protein	A7J297	Streptococcus_phage	2.1e-161	100.0
WP_011888932.1\|356430_356787_+\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	7.9e-59	99.2
WP_011054872.1\|356797_357076_+	hypothetical protein	A7J299	Streptococcus_phage	1.9e-47	100.0
WP_011106640.1\|357072_357417_+	HK97 gp10 family phage protein	A7J2A0	Streptococcus_phage	5.1e-55	98.2
WP_011054870.1\|357420_357780_+	hypothetical protein	A7J2A1	Streptococcus_phage	1.2e-57	98.3
WP_011054869.1\|357791_358391_+\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	1.7e-90	97.1
WP_011888931.1\|358444_358900_+	hypothetical protein	A7J2A3	Streptococcus_phage	5.3e-76	99.3
WP_011888930.1\|358974_359208_+	hypothetical protein	A7J2A4	Streptococcus_phage	1.3e-33	98.7
WP_111688404.1\|359222_363605_+	tape measure protein	A7J2A5	Streptococcus_phage	1.2e-225	74.2
WP_011054865.1\|363616_364459_+	hypothetical protein	A7J2A6	Streptococcus_phage	8.8e-157	97.9
WP_011888928.1\|364468_366448_+\|tail	phage tail protein	A7J2A7	Streptococcus_phage	0.0e+00	92.8
WP_011888927.1\|366444_367560_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-142	74.9
WP_011017395.1\|367574_369479_+	gp58-like family protein	Q938J9	Temperate_phage	1.1e-210	83.7
WP_002988448.1\|369490_369919_+	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_046735270.1\|369921_370560_+	hypothetical protein	A3F662	Streptococcus_phage	2.0e-44	52.7
WP_011017397.1\|370571_370844_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_029714020.1\|370840_371068_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.2e-30	97.3
WP_047149505.1\|371190_372396_+	glucosaminidase domain-containing protein	A7J2B5	Streptococcus_phage	1.5e-202	82.8
WP_047149504.1\|373092_373275_+	hypothetical protein	A3F673	Streptococcus_phage	1.7e-17	73.3
WP_011054967.1\|373501_376330_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.0e-305	55.7
373446:373463	attR	NA	NA	NA	NA
WP_032460474.1\|376445_377519_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	1.3e-16	32.2
WP_002988493.1\|377553_378015_+	hypothetical protein	F8WPT6	Bacillus_phage	1.1e-33	55.1

DBSCAN-SWA_3

539056 : 598405

Streptococcus_pyogenes_phage(56.45%)

holin,integrase,capsid,terminase,tail,tRNA,portal

attL 548178:548193|attR 607459:607474

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032460195.1\|539056_539992_+\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.0e-05	38.5
WP_014407741.1\|539981_541304_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_002983660.1\|541341_542082_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_012560855.1\|542078_543977_+	Stk1 family PASTA domain-containing Ser/Thr kinase	B5LWE2	Feldmannia_species_virus	1.4e-21	30.7
WP_011054833.1\|544099_544792_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_002991890.1\|544788_545793_+	sensor histidine kinase	NA	NA	NA	NA
WP_002983671.1\|545785_546427_+	response regulator transcription factor	NA	NA	NA	NA
WP_023079249.1\|546463_547864_+	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	5.4e-26	43.5
WP_002991882.1\|547863_548241_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
548178:548193	attL	NA	NA	NA	NA
WP_011888673.1\|548258_549200_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.7e-129	77.2
WP_111703176.1\|549327_549960_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.5e-63	54.3
WP_111703177.1\|550015_551341_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	5.3e-116	51.1
WP_002983685.1\|551312_551978_+	ComF family protein	NA	NA	NA	NA
WP_002988974.1\|552057_552606_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_002983693.1\|560378_560912_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_038434191.1\|560991_561768_-	recombination regulator RecX	NA	NA	NA	NA
WP_009880742.1\|561915_563082_-\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	7.0e-80	42.2
WP_043885029.1\|563255_563942_-	hypothetical protein	A0A1P8VVT3	Streptococcus_phage	4.8e-121	99.1
WP_011054825.1\|564112_564265_-	hypothetical protein	A0A1P8VVQ0	Streptococcus_phage	5.2e-20	100.0
WP_011054824.1\|564275_564653_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	4.0e-69	100.0
WP_011528540.1\|564636_564996_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.8e-58	98.3
WP_009881062.1\|565184_565403_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	4.1e-34	100.0
WP_011528542.1\|565497_565749_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.8e-42	100.0
WP_111703179.1\|565929_566247_+	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	1.2e-34	72.4
WP_085613680.1\|566260_567163_+	phage replisome organizer N-terminal domain-containing protein	J7KBV5	Streptococcus_phage	3.0e-118	87.5
WP_063629027.1\|567172_568015_+	ATP-binding protein	A0A1S5S7L9	Streptococcus_phage	1.3e-48	40.7
WP_111703180.1\|568164_568518_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	1.8e-15	53.1
WP_111703181.1\|568498_568753_+	hypothetical protein	Q938N0	Temperate_phage	4.1e-41	97.6
WP_011285577.1\|568774_569257_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	4.1e-50	99.4
WP_111703182.1\|569257_569932_+	ERF family protein	Q938M8	Temperate_phage	2.8e-105	94.6
WP_038433322.1\|569924_570416_+	single-stranded DNA-binding protein	A0A286QNX2	Streptococcus_phage	5.8e-60	74.8
WP_011106686.1\|570421_570625_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_111703183.1\|570624_571065_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	1.3e-79	97.9
WP_011018138.1\|571061_571418_+	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_111703184.1\|571878_572292_+	hypothetical protein	Q938M1	Temperate_phage	1.2e-37	66.7
WP_111703185.1\|572288_572573_+	hypothetical protein	A3F628	Streptococcus_phage	5.9e-33	79.8
WP_111703186.1\|572576_573062_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	1.4e-93	98.8
WP_021340166.1\|573065_573293_+	hypothetical protein	A3F630	Streptococcus_phage	1.9e-26	76.0
WP_011054812.1\|573317_573503_+	hypothetical protein	A0A097PBF0	Streptococcus_pyogenes_phage	7.0e-27	100.0
WP_032461639.1\|573499_573793_+	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	4.2e-50	100.0
WP_032461638.1\|573789_574293_+	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	1.5e-92	99.4
WP_002987493.1\|574289_574460_+	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_032461637.1\|574733_575168_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	2.2e-71	94.4
WP_011285571.1\|575516_575897_+	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
WP_009880266.1\|575886_577161_+\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.1e-251	100.0
WP_009880265.1\|577160_578486_+\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	7.4e-243	100.0
WP_009880264.1\|578454_579363_+\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	4.2e-88	100.0
WP_011054805.1\|579369_579636_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.6e-38	100.0
WP_009880262.1\|579785_580355_+	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	8.5e-71	98.4
WP_009880261.1\|580372_581263_+	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	8.6e-86	99.4
WP_009880260.1\|581274_581568_+	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	2.0e-47	100.0
WP_009880259.1\|581581_581926_+	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.1e-54	100.0
WP_009880258.1\|581922_582234_+	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	2.6e-50	99.0
WP_009880257.1\|582230_582626_+	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	1.8e-59	100.0
WP_009880256.1\|582627_583038_+	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	1.4e-70	100.0
WP_009880255.1\|583049_583556_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	2.6e-79	100.0
WP_009880254.1\|583568_583886_+	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	4.9e-52	100.0
WP_009880253.1\|583858_584317_+	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	2.3e-82	100.0
WP_011054802.1\|584309_586115_+\|tail	tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	8.8e-263	99.7
WP_009880250.1\|586115_587600_+\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	4.3e-292	99.8
WP_011054801.1\|587600_591041_+\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	99.9
WP_009880248.1\|591045_592908_+	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	99.7
WP_009880247.1\|592918_593266_+	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	3.5e-59	100.0
WP_015055952.1\|593415_593739_+	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
WP_011054798.1\|593738_594071_+\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	5.7e-51	100.0
WP_011054797.1\|594072_594837_+	CHAP domain-containing protein	A0A097PAT3	Streptococcus_pyogenes_phage	1.5e-150	100.0
WP_011054796.1\|594848_595451_+	hypothetical protein	A0A097PAX9	Streptococcus_pyogenes_phage	7.8e-91	98.8
WP_011054795.1\|595461_596235_+	hypothetical protein	A0A097PAV0	Streptococcus_pyogenes_phage	3.9e-135	100.0
WP_009880241.1\|596244_596466_+	hypothetical protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
WP_009880240.1\|596465_597125_+	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	8.5e-123	100.0
WP_009880239.1\|597246_598002_-	streptococcal pyrogenic exotoxin SpeA	A0A097PAT7	Streptococcus_pyogenes_phage	2.2e-143	100.0
WP_111703187.1\|598222_598405_+	Paratox	J7KIW4	Streptococcus_phage	1.2e-18	81.4
607459:607474	attR	NA	NA	NA	NA

DBSCAN-SWA_4

699454 : 739516

Streptococcus_phage(70.0%)

holin,integrase,capsid,terminase,tail,portal

attL 702063:702082|attR 737293:737312

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172449955.1\|699454_700306_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_002992620.1\|700298_701141_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|701118_701706_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|701804_702080_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
702063:702082	attL	NA	NA	NA	NA
WP_003051793.1\|702168_703311_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_010922481.1\|703434_703953_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	9.2e-32	45.9
WP_010922480.1\|703964_704720_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922479.1\|704921_705134_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922478.1\|705403_705715_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_010922477.1\|705716_705902_+	hypothetical protein	Q938N3	Temperate_phage	1.3e-20	83.6
WP_011017564.1\|706390_706777_+	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_010922205.1\|706757_706991_+	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_002988354.1\|706987_707128_+	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
WP_002988357.1\|707136_707343_+	hypothetical protein	NA	NA	NA	NA
WP_011528796.1\|707398_707728_+	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_011054700.1\|707730_708657_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_000594115.1\|708653_708854_+	hypothetical protein	NA	NA	NA	NA
WP_011054699.1\|708846_709644_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	1.3e-130	83.8
WP_011054698.1\|710008_710404_+	hypothetical protein	A8ATL9	Listeria_phage	1.4e-19	52.3
WP_011054697.1\|710400_711747_+	PcfJ domain-containing protein	A8ATM0	Listeria_phage	1.0e-122	49.4
WP_011184741.1\|711757_712090_+	hypothetical protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
WP_011054695.1\|712086_712599_+	hypothetical protein	M1PFM2	Streptococcus_phage	1.7e-78	85.9
WP_011054694.1\|712634_712952_+	DUF1372 family protein	A1EAD7	Streptococcus_phage	9.0e-30	71.4
WP_011054693.1\|712948_713104_+	hypothetical protein	NA	NA	NA	NA
WP_011054692.1\|713100_713352_+	hypothetical protein	M1PF60	Streptococcus_phage	1.6e-18	59.0
WP_011528791.1\|713427_713847_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
WP_011054690.1\|713954_714299_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
WP_002994106.1\|714446_714803_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_111703209.1\|714799_716068_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	1.4e-187	75.4
WP_010922467.1\|716060_717554_+	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_002994100.1\|717559_717784_+	hypothetical protein	NA	NA	NA	NA
WP_011054687.1\|717860_718013_+	hypothetical protein	NA	NA	NA	NA
WP_002986828.1\|718005_718272_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011106704.1\|718273_718489_+	hypothetical protein	M1IRA5	Streptococcus_phage	4.1e-26	72.4
WP_011054685.1\|718570_719986_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	1.5e-212	74.0
WP_010922462.1\|720066_720528_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_011054683.1\|720552_721464_+\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	2.9e-113	67.0
WP_010922460.1\|721463_721664_+	hypothetical protein	NA	NA	NA	NA
WP_011054682.1\|721673_722096_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_011054681.1\|722055_722394_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_000032787.1\|722386_722623_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_000573598.1\|722623_722959_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_011054679.1\|722974_723565_+	hypothetical protein	M1PKG8	Streptococcus_phage	1.1e-60	62.5
WP_010922455.1\|723575_723839_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_011054678.1\|723853_724225_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.7e-35	62.4
WP_111703210.1\|724224_726588_+	hypothetical protein	M1NRG5	Streptococcus_phage	2.5e-132	49.9
WP_002992579.1\|726584_727280_+	hypothetical protein	A0A1B1P761	Bacillus_phage	4.7e-07	32.2
WP_168388764.1\|727261_729235_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	2.0e-98	49.6
WP_111703211.1\|729234_730344_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.3e-115	67.8
WP_111703212.1\|730358_732140_+	hypothetical protein	Q938J9	Temperate_phage	3.7e-64	40.1
WP_011528780.1\|732148_732577_+	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	87.9
WP_011528779.1\|732579_733212_+	hypothetical protein	Q938J7	Temperate_phage	4.0e-45	50.5
WP_011017397.1\|733223_733496_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_111703213.1\|733492_733720_+\|holin	phage holin	A7J2B3	Streptococcus_phage	7.6e-31	98.7
WP_014635574.1\|733838_735056_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	1.1e-163	60.1
WP_002985327.1\|735124_735832_-	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_014635573.1\|735942_736701_-	DNase Mf2	NA	NA	NA	NA
WP_014635572.1\|736940_737123_+	hypothetical protein	A3F673	Streptococcus_phage	1.7e-20	80.0
WP_111703214.1\|737653_739516_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.2e-90	33.8
737293:737312	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1209664 : 1220267

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111703355.1\|1209664_1210807_-	cysteine desulfurase	H7BUW1	unidentified_phage	7.8e-15	31.7
WP_111703357.1\|1211041_1211482_+	hypothetical protein	NA	NA	NA	NA
WP_111703359.1\|1211511_1212780_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_111703361.1\|1212867_1214220_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	3.5e-30	24.0
WP_011054350.1\|1214440_1214782_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	1.3e-18	39.3
WP_002990262.1\|1214842_1216009_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002985140.1\|1216102_1216789_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985142.1\|1216785_1217949_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_011054348.1\|1218056_1220267_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.1

DBSCAN-SWA_6

1437885 : 1486244

Klebsiella_phage(10.0%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_042361478.1\|1437885_1439019_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_111703453.1\|1439140_1440643_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	1.3e-73	41.1
WP_111703754.1\|1440832_1441426_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_111703455.1\|1441422_1442250_-	DNA-formamidopyrimidine glycosylase	A0A1V0CNR6	Kaumoebavirus	1.6e-14	28.2
WP_111703457.1\|1442428_1443295_-	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_128650799.1\|1443383_1443452_+	peptide pheromone SHP2	NA	NA	NA	NA
WP_023605037.1\|1444355_1444625_+	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_009880375.1\|1444972_1445371_-	hypothetical protein	NA	NA	NA	NA
WP_032466306.1\|1446784_1447186_-	hypothetical protein	NA	NA	NA	NA
WP_111703458.1\|1447379_1447661_-	hypothetical protein	NA	NA	NA	NA
WP_111703460.1\|1447710_1447905_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_003060803.1\|1448198_1448399_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_111703462.1\|1448411_1448639_-\|bacteriocin	bacteriocin BlpM	NA	NA	NA	NA
WP_002987564.1\|1449861_1450044_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002985741.1\|1451248_1451725_-	NUDIX hydrolase	NA	NA	NA	NA
WP_002985743.1\|1451745_1452642_-	GTPase Era	NA	NA	NA	NA
WP_002985746.1\|1452761_1453169_-	diacylglycerol kinase	NA	NA	NA	NA
WP_111703464.1\|1453149_1453647_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_111703466.1\|1453805_1454381_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_010921967.1\|1454426_1455479_-	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_111703468.1\|1455637_1457410_-	oleate hydratase	NA	NA	NA	NA
WP_111703470.1\|1457723_1458905_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
WP_002985757.1\|1459060_1459276_-	YozE family protein	NA	NA	NA	NA
WP_111703472.1\|1459272_1459782_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_011106872.1\|1459854_1460712_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985763.1\|1460820_1461378_-	ribosome recycling factor	NA	NA	NA	NA
WP_002985765.1\|1461407_1462136_-	UMP kinase	NA	NA	NA	NA
WP_002985768.1\|1462458_1463148_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002990800.1\|1463253_1463679_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_030126115.1\|1463922_1464276_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_014635327.1\|1464345_1466751_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_002990808.1\|1466967_1467774_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_111703474.1\|1467921_1468776_-	metal ABC transporter permease	NA	NA	NA	NA
WP_002985780.1\|1468776_1469502_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_011017446.1\|1469565_1470498_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014635325.1\|1470643_1471291_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_011184241.1\|1471389_1471731_-	hypothetical protein	NA	NA	NA	NA
WP_111703476.1\|1471884_1472580_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_111703478.1\|1472599_1472851_-	hypothetical protein	NA	NA	NA	NA
WP_111703480.1\|1472850_1473405_-	NUDIX hydrolase	NA	NA	NA	NA
WP_011889106.1\|1473438_1474821_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	3.8e-32	36.4
WP_111703482.1\|1474993_1476331_-	MFS transporter	NA	NA	NA	NA
WP_111703484.1\|1476663_1477623_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_111703486.1\|1477698_1478397_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	3.2e-11	25.6
WP_002990844.1\|1478389_1478626_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_111703488.1\|1479349_1480318_+	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	9.0e-89	52.6
WP_111703490.1\|1480829_1481534_+	hypothetical protein	NA	NA	NA	NA
WP_111703491.1\|1484119_1484518_+	hypothetical protein	NA	NA	NA	NA
WP_111703493.1\|1485950_1486244_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1509046 : 1514920

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_047235166.1\|1509046_1509874_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.4e-127	79.1
WP_002990897.1\|1509947_1510304_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.1e-39	65.0
WP_111703512.1\|1510603_1511233_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002985833.1\|1511279_1511672_-	hypothetical protein	NA	NA	NA	NA
WP_002985836.1\|1511698_1512562_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
WP_011054221.1\|1512566_1512890_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.0e-28	62.3
WP_011528291.1\|1513391_1514267_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.8e-72	47.9
WP_010921930.1\|1514284_1514920_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4

DBSCAN-SWA_8

1663881 : 1671959

Staphylococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009880696.1\|1663881_1664172_-	helix-turn-helix domain-containing protein	A0A0N7GFG6	Staphylococcus_phage	3.7e-22	56.0
WP_172449975.1\|1664226_1665578_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.7e-64	49.8
WP_012561030.1\|1665695_1666010_-	hypothetical protein	NA	NA	NA	NA
WP_111703608.1\|1666398_1666635_+	hypothetical protein	NA	NA	NA	NA
WP_111703610.1\|1667026_1668784_+	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	2.7e-35	28.0
WP_111703612.1\|1668816_1669383_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.3e-31	42.4
WP_111703614.1\|1669415_1670684_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	4.5e-96	47.1
WP_111703616.1\|1671275_1671959_+	exotoxin	A0EX09	Staphylococcus_phage	7.9e-15	35.4

DBSCAN-SWA_9

1781234 : 1801505

Streptococcus_phage(46.67%)

holin,integrase

attL 1784433:1784453|attR 1798806:1798826

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111703699.1\|1781234_1782455_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.8e-05	24.3
WP_111703701.1\|1782465_1784448_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	3.0e-62	30.1
1784433:1784453	attL	NA	NA	NA	NA
WP_111703703.1\|1784542_1785688_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	1.9e-85	45.4
WP_011185066.1\|1785942_1786086_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003058809.1\|1786946_1787714_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	3.6e-72	83.1
WP_002992503.1\|1787867_1788074_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
WP_080277853.1\|1788107_1788875_+	hypothetical protein	A0A0A7S0G2	Clostridium_phage	5.0e-26	53.7
WP_065355060.1\|1788884_1789508_+	antirepressor	A0A1W6JPC3	Staphylococcus_phage	1.7e-40	43.3
WP_000648623.1\|1789534_1789777_+	hypothetical protein	NA	NA	NA	NA
WP_000132665.1\|1790035_1790209_+	hypothetical protein	NA	NA	NA	NA
WP_000074663.1\|1790426_1790600_+	hypothetical protein	NA	NA	NA	NA
WP_011285276.1\|1791221_1791554_+	hypothetical protein	NA	NA	NA	NA
WP_021340709.1\|1791553_1791745_+	hypothetical protein	NA	NA	NA	NA
WP_003058810.1\|1791756_1792086_+	hypothetical protein	NA	NA	NA	NA
WP_010922766.1\|1792088_1792361_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
WP_011285278.1\|1792361_1793228_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	6.1e-121	73.8
WP_011285279.1\|1793239_1794634_+	phage protein	A0A1W6JQD6	Staphylococcus_phage	1.3e-48	38.1
WP_011285280.1\|1794927_1795182_+	hypothetical protein	NA	NA	NA	NA
WP_011285281.1\|1795178_1795352_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	8.6e-11	59.6
WP_014635784.1\|1795357_1795531_+	hypothetical protein	NA	NA	NA	NA
WP_014407945.1\|1795532_1796042_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.1e-29	63.5
WP_002992480.1\|1796116_1796605_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
WP_020905578.1\|1797008_1797371_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_014407948.1\|1797345_1797729_+	DUF1492 domain-containing protein	Q938L8	Temperate_phage	6.4e-14	40.2
WP_111703705.1\|1798949_1801505_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	3.0e-43	23.2
1798806:1798826	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_LS483330.1|WP_014635572.1|736940_737123_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483330.1|WP_014635572.1|736940_737123_+|hypothetical-protein

736940_737123_+

60 aa aa

699454-739516

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_LS483330_2	TypeII	2.1\|1063540\|30\|NZ_LS483330\|CRISPRCasFinder,CRT	1063540-1063569	30	737052-737023	1

1. spacer 2.1|1063540|30|NZ_LS483330|CRISPRCasFinder,CRT matches to NZ_LS483330 position: 737052-737023, mismatch: 1

cattcggcaacacataatcaaaaatctgtc	CRISPR spacer
cattcggcaaaacataatcaaaaatctgtc	Protospacer
********** *******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483330

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information