CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483352	Streptococcus pyogenes strain NCTC12052 chromosome 1	2 crisprs	DinG,csm6,cas9,cas1,cas2,csn2,cas3,DEDDh,csa3	0	2	9	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483352_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483352_1

830171-830338

TypeII

II-A

Consensus_repeat	Method
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CRISPRCasFinder

2 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_LS483352_1

>merge|NZ_LS483352|1|830171-830338|CRISPRCasFinder
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACTCAAGAGTGAGTCCAGAACCACCAGCGAATGTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAACCACTAGACATCTCAACATCTGGAACGGGATGTTTTAGAGCTATGCTATTTTGAATGGTCTCCATTC

>NZ_LS483352|1|1|830171-830338|CRISPRCasFinder
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	TCAAGAGTGAGTCCAGAACCACCAGCGAAT
GTTTTAGAGCTATGCTGTTTTGAATGGTCCCAAAAC	CACTAGACATCTCAACATCTGGAACGGGAT
GTTTTAGAGCTATGCTATTTTGAATGGTCTCCATTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483352.1\|WP_111685731.1\|839299_840949_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483352.1\|WP_023080005.1\|824105_828209_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_LS483352.1\|WP_002989949.1\|829405_830068_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_LS483352.1\|WP_021733386.1\|836578_837004_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483352.1\|WP_002989931.1\|838336_839164_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	unknown	unknown	gnl\|CDD\|226239
NZ_LS483352.1\|WP_111685729.1\|834785_835223_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483352.1\|WP_002989934.1\|837022_837514_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483352.1\|WP_111685874.1\|833319_834600_+\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|237171
NZ_LS483352.1\|WP_032460891.1\|828208_829078_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NZ_LS483352.1\|WP_023610292.1\|822994_823627_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483352.1\|WP_023079997.1\|822230_822995_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483352.1\|WP_002984836.1\|840952_841741_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483352.1\|WP_111685728.1\|830981_832814_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483352.1\|WP_002989951.1\|829074_829416_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_LS483352.1\|WP_023080006.1\|819634_820276_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483352.1\|WP_023080002.1\|820338_821469_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483352.1\|WP_011106808.1\|818155_819511_+\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NZ_LS483352.1\|WP_023080001.1\|821478_822231_+\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483352.1\|WP_011528593.1\|837530_838340_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483352.1\|WP_111685730.1\|835352_836372_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411

Protein	Function_ID	Function_description	E-value
NZ_LS483352.1\|WP_111685731.1\|839299_840949_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	1.26478e-77
NZ_LS483352.1\|WP_023080005.1\|824105_828209_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LS483352.1\|WP_002989949.1\|829405_830068_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.6851e-120
NZ_LS483352.1\|WP_021733386.1\|836578_837004_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	5.21553e-31
NZ_LS483352.1\|WP_002989931.1\|838336_839164_+\|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID	gnl\|CDD\|226239	COG3716, ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism].	1.55707e-109
NZ_LS483352.1\|WP_111685729.1\|834785_835223_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	1.80871e-84
NZ_LS483352.1\|WP_002989934.1\|837022_837514_+\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NZ_LS483352.1\|WP_111685874.1\|833319_834600_+\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	1.09769e-18
NZ_LS483352.1\|WP_032460891.1\|828208_829078_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	4.0115e-131
NZ_LS483352.1\|WP_023610292.1\|822994_823627_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	7.0655e-88
NZ_LS483352.1\|WP_023079997.1\|822230_822995_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.30945e-126
NZ_LS483352.1\|WP_111685728.1\|830981_832814_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483352.1\|WP_002989951.1\|829074_829416_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.79e-58
NZ_LS483352.1\|WP_002984836.1\|840952_841741_+\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	5.79862e-82
NZ_LS483352.1\|WP_023080002.1\|820338_821469_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483352.1\|WP_011106808.1\|818155_819511_+\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NZ_LS483352.1\|WP_023080001.1\|821478_822231_+\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	6.29729e-107
NZ_LS483352.1\|WP_011528593.1\|837530_838340_+\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	2.10148e-76
NZ_LS483352.1\|WP_111685730.1\|835352_836372_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	5.17879e-104

>NZ_LS483352.1|WP_002989949.1|829405_830068_+|type-II-A-CRISPR-associated-protein-Csn2
MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSELKFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKNMV
>NZ_LS483352.1|WP_002989951.1|829074_829416_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NZ_LS483352.1|WP_032460891.1|828208_829078_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVKSQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTLFGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFVYNGKEMYLTNIVSDYTKKVVKALNNEGKGVPEFRI
>NZ_LS483352.1|WP_023080005.1|824105_828209_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKLKVLGNTDRHGIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKVDLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPYQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNTSLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKKYANLFDDKVMKQLKRRHYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLINDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQTVKIVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIIKLPKYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAKNIIHLFTLTNLGAPAAFKYFDTTIERNRYKSIKEVLDATLIHQSITGLYETRIDLSQLGGD
>NZ_LS483352.1|WP_023610292.1|822994_823627_+|TIGR01906-family-membrane-protein
MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFVTRLEFADFHSSADGLKHFADVKWLFHLTQVVFLGLLYPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDSSWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE
>NZ_LS483352.1|WP_023079997.1|822230_822995_+|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNNTTRTPEMVQSMLANQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYETLAIATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NZ_LS483352.1|WP_023080001.1|821478_822231_+|acyl-[acyl-carrier-protein]-thioesterase
MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGRSNNNILVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGCLLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQIISDGQLNAQAMIEWRAIKPIESETD
>NZ_LS483352.1|WP_023080002.1|820338_821469_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQEFYSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPEKIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTITNLKAAGFHNISIDLIYALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEERYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483352.1|WP_023080006.1|819634_820276_+|hypothetical-protein
MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDIQKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAVNEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLADMQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP
>NZ_LS483352.1|WP_011106808.1|818155_819511_+|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
>NZ_LS483352.1|WP_111685728.1|830981_832814_+|elongation-factor-4
MNSQDFKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIEVSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDDDTKK
>NZ_LS483352.1|WP_111685874.1|833319_834600_+|LPXTG-cell-wall-anchor-domain-containing-protein
MNEYIKQHKEHDQEWKRELTRGIQQKLLDGKDGRDGAQGLAGERGATGPVGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGKQGDRGEAGPQGPRGEQGDRGKDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPDHSKDVTPAPQNPSNRGLNKPQTQGGNQFAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN
>NZ_LS483352.1|WP_111685729.1|834785_835223_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
METSEELKQRIGDLSYEVTQHAATESPFTGEYDHFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
>NZ_LS483352.1|WP_111685730.1|835352_836372_+|YeiH-family-putative-sulfate-export-transporter
MSTNLRKLPGLLLCLLLALPAWCLGRLFLIIGAPVFAILLGMLLALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTIATALLVAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNMLAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVSADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQLSLGIW
>NZ_LS483352.1|WP_021733386.1|836578_837004_+|PTS-sugar-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD
>NZ_LS483352.1|WP_002989934.1|837022_837514_+|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NZ_LS483352.1|WP_011528593.1|837530_838340_+|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITRGAINKQTTFDSKESEEEDFFA
>NZ_LS483352.1|WP_002989931.1|838336_839164_+|PTS-mannose/fructose/sorbose-transporter-family-subunit-IID
MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTLLPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAITAVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHYYSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKGAKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC
>NZ_LS483352.1|WP_111685731.1|839299_840949_+|sensor-histidine-kinase
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNAFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGHYLMIIKPMIDQNQLMGYAFLVMSGKDFIHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPKLFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>NZ_LS483352.1|WP_002984836.1|840952_841741_+|response-regulator-transcription-factor
MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAHFQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC

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Crispr_ID: NZ_LS483352_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483352_2

1008992-1009093

Orphan

Consensus_repeat	Method
AATAATTGGTATAGTCTAATTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483352_2

>merge|NZ_LS483352|2|1008992-1009093|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATACCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACATAAAATTGGTATAGTCTAATTATA

>NZ_LS483352|2|2|1008992-1009093|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATA	CCGATAAAAACAGTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACA
TAAAATTGGTATAGTCTAATTATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483352.1\|WP_014635492.1\|1001608_1002844_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_LS483352.1\|WP_002984444.1\|1011456_1012470_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483352.1\|WP_002984447.1\|1009891_1011394_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_LS483352.1\|WP_009880829.1\|1003213_1003987_-\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_LS483352.1\|WP_002989648.1\|997318_999637_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_LS483352.1\|WP_002984441.1\|1012549_1015660_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_LS483352.1\|WP_011054546.1\|1019044_1019233_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|269889
NZ_LS483352.1\|WP_002989607.1\|1017839_1018454_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_LS483352.1\|WP_002984469.1\|996707_996956_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_LS483352.1\|WP_002989617.1\|1015844_1016216_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_LS483352.1\|WP_002992415.1\|1005208_1005838_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LS483352.1\|WP_002992425.1\|1016215_1016914_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LS483352.1\|WP_002992417.1\|1005847_1006489_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_LS483352.1\|WP_111685758.1\|1006595_1006931_-\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_LS483352.1\|WP_014635494.1\|1004356_1005193_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_LS483352.1\|WP_020833516.1\|1019347_1020136_-\|streptococcal-pyrogenic-exotoxin-SpeL	unknown	unknown	gnl\|CDD\|280949
NZ_LS483352.1\|WP_002984449.1\|1009116_1009674_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NZ_LS483352.1\|WP_002984433.1\|1016923_1017709_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483352.1\|WP_038432363.1\|1000166_1001489_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_LS483352.1\|WP_002984451.1\|1007126_1008941_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729

Protein	Function_ID	Function_description	E-value
NZ_LS483352.1\|WP_014635492.1\|1001608_1002844_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	5.43501e-96
NZ_LS483352.1\|WP_002984444.1\|1011456_1012470_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483352.1\|WP_002984447.1\|1009891_1011394_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_LS483352.1\|WP_009880829.1\|1003213_1003987_-\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	2.06073e-97
NZ_LS483352.1\|WP_002989648.1\|997318_999637_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483352.1\|WP_002984441.1\|1012549_1015660_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_LS483352.1\|WP_011054546.1\|1019044_1019233_-\|hypothetical-protein	gnl\|CDD\|269889	cd06603, GH31_GANC_GANAB_alpha, neutral alpha-glucosidase C, neutral alpha-glucosidase AB. This subgroup includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae.	0.00788697
NZ_LS483352.1\|WP_002989607.1\|1017839_1018454_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NZ_LS483352.1\|WP_002984469.1\|996707_996956_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_LS483352.1\|WP_002989617.1\|1015844_1016216_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.0536e-49
NZ_LS483352.1\|WP_002992415.1\|1005208_1005838_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.61041e-111
NZ_LS483352.1\|WP_002992425.1\|1016215_1016914_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.0817e-63
NZ_LS483352.1\|WP_002992417.1\|1005847_1006489_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.99371e-71
NZ_LS483352.1\|WP_111685758.1\|1006595_1006931_-\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	7.28705e-64
NZ_LS483352.1\|WP_014635494.1\|1004356_1005193_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.58337e-109
NZ_LS483352.1\|WP_020833516.1\|1019347_1020136_-\|streptococcal-pyrogenic-exotoxin-SpeL	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	2.95713e-08
NZ_LS483352.1\|WP_002984449.1\|1009116_1009674_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NZ_LS483352.1\|WP_038432363.1\|1000166_1001489_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_LS483352.1\|WP_002984451.1\|1007126_1008941_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0

>NZ_LS483352.1|WP_002984451.1|1007126_1008941_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_LS483352.1|WP_111685758.1|1006595_1006931_-|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYIYEDGLLLICPMCAFEWTPGEEATEEEGLVVLDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NZ_LS483352.1|WP_002992417.1|1005847_1006489_-|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_LS483352.1|WP_002992415.1|1005208_1005838_-|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_LS483352.1|WP_014635494.1|1004356_1005193_-|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKDRQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NZ_LS483352.1|WP_009880829.1|1003213_1003987_-|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NZ_LS483352.1|WP_014635492.1|1001608_1002844_+|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVSVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQITPIAKKQLHHTHYRIVKM
>NZ_LS483352.1|WP_038432363.1|1000166_1001489_+|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQIVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFVLMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_LS483352.1|WP_002989648.1|997318_999637_-|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_LS483352.1|WP_002984469.1|996707_996956_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN
>NZ_LS483352.1|WP_002984449.1|1009116_1009674_-|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_LS483352.1|WP_002984447.1|1009891_1011394_-|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_LS483352.1|WP_002984444.1|1011456_1012470_-|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_LS483352.1|WP_002984441.1|1012549_1015660_-|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_LS483352.1|WP_002989617.1|1015844_1016216_+|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_LS483352.1|WP_002992425.1|1016215_1016914_+|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDNSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_LS483352.1|WP_002984433.1|1016923_1017709_+|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_LS483352.1|WP_002989607.1|1017839_1018454_-|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_LS483352.1|WP_011054546.1|1019044_1019233_-|hypothetical-protein
MLTYDEFKQAIDDGYIVGDTVMIVRKNGQIFDYVLPHEEARNGEVVTEEKVEEVMVELDYIK
>NZ_LS483352.1|WP_020833516.1|1019347_1020136_-|streptococcal-pyrogenic-exotoxin-SpeL
MRIFLHQNCRLVNMSTTFFIVVLSLMVFSVRMVSAEGTINIKDIYPPRWDVDKTLSPTTLREIYNRDTIKKVNKPITGKRGTQVIMDAQHKTKVWEFDDYNFIISSNLHPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIYMNVFIDGHKKDDTSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYDSKVLSGNWEFHGSGEKEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MK448972	Streptococcus phage Javan520, complete genome	12869-12898	0	1.0
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MK448763	Streptococcus phage Javan451, complete genome	13647-13676	0	1.0
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MK448777	Streptococcus phage Javan491, complete genome	13529-13558	0	1.0
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448944	Streptococcus phage Javan452, complete genome	12352-12381	1	0.967
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448672	Streptococcus phage Javan117, complete genome	7933-7962	1	0.967
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448849	Streptococcus phage Javan128, complete genome	7837-7866	1	0.967
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448850	Streptococcus phage Javan132, complete genome	12662-12691	1	0.967
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MK448845	Streptococcus phage Javan118, complete genome	14951-14980	2	0.933
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448675	Streptococcus phage Javan129, complete genome	12142-12171	2	0.933
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448673	Streptococcus phage Javan119, complete genome	11438-11467	2	0.933
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448845	Streptococcus phage Javan118, complete genome	9816-9845	3	0.9
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448771	Streptococcus phage Javan481, complete genome	8088-8117	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448973	Streptococcus phage Javan522, complete genome	9993-10022	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448775	Streptococcus phage Javan489, complete genome	11977-12006	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448969	Streptococcus phage Javan514, complete genome	10959-10988	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448794	Streptococcus phage Javan525, complete genome	10172-10201	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448972	Streptococcus phage Javan520, complete genome	8013-8042	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448763	Streptococcus phage Javan451, complete genome	9206-9235	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448774	Streptococcus phage Javan487, complete genome	8073-8102	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448778	Streptococcus phage Javan493, complete genome	10008-10037	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448773	Streptococcus phage Javan485, complete genome	10959-10988	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448958	Streptococcus phage Javan486, complete genome	10313-10342	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448777	Streptococcus phage Javan491, complete genome	8304-8333	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448765	Streptococcus phage Javan459, complete genome	10172-10201	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK449010	Streptococcus phage Javan90, complete genome	10522-10551	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	MK448833	Streptococcus phage Javan87, complete genome	10522-10551	4	0.867
NZ_LS483352_1	1.2\|830273\|30\|NZ_LS483352\|CRISPRCasFinder	830273-830302	30	NZ_CP010870	Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence	108515-108544	6	0.8
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	NC_014389	Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence	291729-291758	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	JQ692107	Vibrio vulnificus phage SSP002, complete genome	39080-39109	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MN215888	Vibrio phage vB_VpaS_HCMJ, complete genome	39192-39221	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MF754116	Vibrio phage vB_VpaS_KF6, complete genome	37281-37310	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MF754115	Vibrio phage vB_VpaS_KF5, complete genome	39198-39227	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MG602476	Vibrio phage VVP001, complete genome	35844-35873	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	MH925090	UNVERIFIED: Vibrio phage ValLY_3, complete genome	32119-32148	8	0.733
NZ_LS483352_1	1.1\|830207\|30\|NZ_LS483352\|CRISPRCasFinder	830207-830236	30	NZ_LN868946	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence	116915-116944	10	0.667

1. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

2. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

3. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 0, identity: 1.0

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagtccagaaccaccagcgaat	Protospacer
******************************

4. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

5. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

6. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

7. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 1, identity: 0.967

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggaacgggat	Protospacer
*.****************************

8. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 2, identity: 0.933

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtgagaccagaaccaccagcaaat	Protospacer
*********** **************.***

9. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 2, identity: 0.933

cactagacatctcaacatctggaacgggat	CRISPR spacer
cactagacatctcaacatctggaacaggtt	Protospacer
*************************.** *

10. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 2, identity: 0.933

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatttcaacatctggaacgggat	Protospacer
*.********.*******************

11. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 3, identity: 0.9

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatttcaacatctggaacgggtt	Protospacer
*.********.***************** *

12. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

13. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

14. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

15. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

16. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

17. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

18. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

19. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

20. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

21. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

22. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

23. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacaggtt	Protospacer
*..**********************.** *

24. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgttagacatctcaacatctggaacagggt	Protospacer
*..**********************.**.*

25. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggtacaggtt	Protospacer
*.******************** **.** *

26. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 4, identity: 0.867

cactagacatctcaacatctggaacgggat	CRISPR spacer
cgctagacatctcaacatctggtacaggtt	Protospacer
*.******************** **.** *

27. spacer 1.2|830273|30|NZ_LS483352|CRISPRCasFinder matches to NZ_CP010870 (Confluentimicrobium sp. EMB200-NS6 strain EMBL200_NS6 plasmid pNS6001, complete sequence) position: , mismatch: 6, identity: 0.8

cactaga----catctcaacatctggaacgggat	CRISPR spacer
----agagttccatctcaagatctggcacgggat	Protospacer
    ***    ******** ****** *******

28. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to NC_014389 (Butyrivibrio proteoclasticus B316 plasmid pCY360, complete sequence) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
tcaagagtcattccagaaccaccaaatgcc	Protospacer
******** * *************.  . .

29. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to JQ692107 (Vibrio vulnificus phage SSP002, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

30. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MN215888 (Vibrio phage vB_VpaS_HCMJ, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

31. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MF754116 (Vibrio phage vB_VpaS_KF6, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

32. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MF754115 (Vibrio phage vB_VpaS_KF5, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

33. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MG602476 (Vibrio phage VVP001, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

34. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to MH925090 (UNVERIFIED: Vibrio phage ValLY_3, complete genome) position: , mismatch: 8, identity: 0.733

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gtaagggtgagtccagaacaaccagacgac	Protospacer
 .***.************* *****  .*.

35. spacer 1.1|830207|30|NZ_LS483352|CRISPRCasFinder matches to NZ_LN868946 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence) position: , mismatch: 10, identity: 0.667

tcaagagtgagtccagaaccaccagcgaat	CRISPR spacer
gttcagccgaatccagaaccaccagcgaag	Protospacer
 .  .. .**.******************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36638 : 48952

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109828667.1\|36638_40364_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	6.0e-40	27.0
WP_023080049.1\|40524_41979_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-54	32.9
WP_111685626.1\|42006_43029_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	9.0e-63	41.4
WP_002986700.1\|43196_43751_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_023610065.1\|43934_45482_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	3.4e-45	52.4
WP_002987712.1\|45540_46665_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_023080273.1\|46917_48183_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002987716.1\|48460_48952_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.2e-18	42.3

DBSCAN-SWA_2

88112 : 104598

Streptococcus_phage(62.5%)

holin,integrase,tRNA

attL 83484:83498|attR 99475:99489

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
83484:83498	attL	NA	NA	NA	NA
WP_010921791.1\|88112_88832_+	metal ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-15	26.8
WP_021340473.1\|88824_89640_+	metal ABC transporter permease	NA	NA	NA	NA
WP_020833194.1\|89679_90063_-	HIT family protein	NA	NA	NA	NA
WP_032465792.1\|90226_91372_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	5.1e-99	50.0
WP_111685629.1\|91626_91770_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_111685630.1\|92631_93399_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	2.5e-73	84.9
WP_002992503.1\|93552_93759_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
WP_111685631.1\|93792_93993_+	helix-turn-helix transcriptional regulator	A0A1S5SE31	Streptococcus_phage	1.0e-10	55.0
WP_111685632.1\|94013_94421_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	7.7e-50	70.1
WP_111685633.1\|94434_95052_+	Rha family transcriptional regulator	A0A159B6D5	Gordonia_phage	2.2e-11	38.8
WP_111685634.1\|95296_95629_+	hypothetical protein	NA	NA	NA	NA
WP_003058793.1\|95625_95847_+	hypothetical protein	NA	NA	NA	NA
WP_111685635.1\|95849_96041_+	hypothetical protein	NA	NA	NA	NA
WP_000174505.1\|96052_96382_+	hypothetical protein	NA	NA	NA	NA
WP_001100459.1\|96384_96657_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	6.1e-19	60.0
WP_111685636.1\|96657_97515_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	7.6e-124	74.5
WP_111685637.1\|97483_99172_+	DNA primase	A0A1X9I717	Streptococcus_phage	2.5e-259	82.1
WP_023610068.1\|99458_99632_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	3.9e-11	61.4
99475:99489	attR	NA	NA	NA	NA
WP_003058787.1\|99637_99811_+	hypothetical protein	NA	NA	NA	NA
WP_111674798.1\|99812_100322_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	5.5e-29	62.5
WP_014407946.1\|100395_100884_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	2.0e-44	54.3
WP_111685638.1\|101289_101652_+	DUF1492 domain-containing protein	A0A2H4JFS1	uncultured_Caudovirales_phage	3.0e-05	29.9
WP_111685639.1\|101626_102010_+	DUF1492 domain-containing protein	Q938L8	Temperate_phage	4.9e-14	42.5
WP_111685640.1\|102218_102854_+	hypothetical protein	NA	NA	NA	NA
WP_111685641.1\|102816_103068_+	hypothetical protein	NA	NA	NA	NA
WP_023610094.1\|103338_104598_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	2.6e-72	40.0

DBSCAN-SWA_3

336592 : 433522

Streptococcus_phage(20.0%)

bacteriocin,tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111685664.1\|336592_337183_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.4e-54	55.7
WP_002985847.1\|337674_337950_+	YlbG family protein	NA	NA	NA	NA
WP_010921930.1\|338198_338834_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4
WP_093974840.1\|338851_339727_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.3e-65	44.5
WP_020833285.1\|339745_339985_+	tpl protein	NA	NA	NA	NA
WP_002985838.1\|340389_340713_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_023609789.1\|340717_341581_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	5.5e-114	74.3
WP_111685665.1\|341607_342000_+	hypothetical protein	NA	NA	NA	NA
WP_011528296.1\|342046_342676_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_111685666.1\|342974_343331_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.8e-39	65.0
WP_021340916.1\|343404_344232_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.7e-128	79.9
WP_168393657.1\|344464_345646_+	L-lactate oxidase	NA	NA	NA	NA
WP_111685668.1\|345911_350855_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_172450110.1\|351248_351524_+	hypothetical protein	NA	NA	NA	NA
WP_002985820.1\|351625_352333_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_111685669.1\|352572_354573_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-87	35.1
WP_010921941.1\|355067_356081_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.5e-97	53.7
WP_023610055.1\|356084_356573_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_063632599.1\|356539_358720_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	2.5e-171	43.3
WP_111685670.1\|358923_359676_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_111685872.1\|360133_360538_+	hypothetical protein	NA	NA	NA	NA
WP_002990852.1\|360725_360977_+	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|362028_362265_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_111685671.1\|362257_362956_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.2e-10	25.2
WP_111685672.1\|363031_363991_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002993065.1\|364323_365661_+	MFS transporter	NA	NA	NA	NA
WP_111685673.1\|365833_367216_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	1.4e-31	36.0
WP_002985793.1\|367246_367801_+	NUDIX hydrolase	NA	NA	NA	NA
WP_021340729.1\|367800_368052_+	hypothetical protein	NA	NA	NA	NA
WP_010921957.1\|368070_368766_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_111685674.1\|368916_369258_+	hypothetical protein	NA	NA	NA	NA
WP_023078622.1\|369357_370005_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_004218965.1\|370150_371083_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|371146_371872_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_011017448.1\|371872_372727_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002990808.1\|372874_373681_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_111685675.1\|373897_376303_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_010921962.1\|376372_376726_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002990800.1\|376969_377395_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|377500_378190_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|378511_379240_+	UMP kinase	NA	NA	NA	NA
WP_002985763.1\|379268_379826_+	ribosome recycling factor	NA	NA	NA	NA
WP_038433941.1\|379934_380792_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002990794.1\|380864_381374_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|381370_381586_+	YozE family protein	NA	NA	NA	NA
WP_111685676.1\|381741_382923_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
WP_111685677.1\|383236_385009_+	oleate hydratase	NA	NA	NA	NA
WP_002990786.1\|385167_386220_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_009880369.1\|386265_386841_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_032467023.1\|386999_387497_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|387477_387885_+	diacylglycerol kinase	NA	NA	NA	NA
WP_002985743.1\|388004_388901_+	GTPase Era	NA	NA	NA	NA
WP_002993018.1\|388921_389398_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014635333.1\|390559_391006_-	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	4.1e-12	36.0
WP_011528336.1\|391228_391939_-\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
WP_002994577.1\|392043_392280_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_002994580.1\|392577_392802_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_002994581.1\|392779_392956_+	hypothetical protein	NA	NA	NA	NA
WP_157261042.1\|393312_393561_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_028797129.1\|394171_394399_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002994587.1\|394447_394765_+	hypothetical protein	NA	NA	NA	NA
WP_020833317.1\|394830_395112_+\|transposase	transposase	NA	NA	NA	NA
WP_111685678.1\|395144_395600_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.8e-13	34.0
WP_002987929.1\|395754_395970_+\|transposase	transposase	U5P429	Shigella_phage	7.0e-10	45.5
WP_002992578.1\|397912_398662_+	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	2.1e-21	28.0
WP_014635339.1\|398662_399997_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_011017462.1\|400144_400270_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_020833322.1\|401722_403876_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.7e-43	28.3
WP_002994504.1\|405201_405447_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|405461_405644_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_012560514.1\|406838_407066_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_003060803.1\|407078_407279_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_011054252.1\|407817_408099_+	hypothetical protein	NA	NA	NA	NA
WP_032467019.1\|408292_408694_+	hypothetical protein	NA	NA	NA	NA
WP_111685679.1\|408944_410015_+	hypothetical protein	NA	NA	NA	NA
WP_111685680.1\|410107_410506_+	histidine kinase	NA	NA	NA	NA
WP_111685681.1\|410775_411045_-	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_128650799.1\|411958_412027_-	peptide pheromone SHP2	NA	NA	NA	NA
WP_002990747.1\|412115_412982_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_002990742.1\|413153_413981_+	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	5.1e-16	27.5
WP_002994141.1\|413977_414571_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_111685682.1\|414760_416263_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	1.5e-74	41.3
WP_111685683.1\|416384_417578_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_002990729.1\|417574_417721_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_002985700.1\|417766_418003_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_111685684.1\|418096_420430_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.5e-89	39.6
WP_002994152.1\|420432_420900_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	5.7e-41	57.0
WP_010921981.1\|420905_421625_+	glutaminyl-peptide cyclotransferase	NA	NA	NA	NA
WP_002994169.1\|421741_422389_-	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_002985692.1\|422438_423365_-	DUF979 domain-containing protein	NA	NA	NA	NA
WP_011017476.1\|423364_424048_-	DUF969 domain-containing protein	NA	NA	NA	NA
WP_032464862.1\|424258_425185_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	3.4e-77	47.5
WP_020904973.1\|425329_425707_-	VOC family protein	NA	NA	NA	NA
WP_002985684.1\|425717_426383_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_002985682.1\|426431_427517_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_111685685.1\|427690_428692_+	catabolite control protein A	C6ZCU4	Enterobacteria_phage	3.6e-24	28.5
WP_002985678.1\|428822_429821_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_111685686.1\|429822_431157_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_111685687.1\|431578_433522_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	4.7e-121	38.7

DBSCAN-SWA_4

534507 : 608686

Temperate_phage(43.86%)

integrase,terminase,tail,tRNA,holin,capsid,portal

attL 541212:541229|attR 612722:612739

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032467059.1\|534507_535632_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_101248318.1\|535700_536798_+	peptide chain release factor 2	NA	NA	NA	NA
WP_002985455.1\|536817_537510_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.0e-30	35.6
WP_023610225.1\|537502_538432_+	ABC transporter permease	NA	NA	NA	NA
WP_076707733.1\|538741_539440_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.0e-78	62.9
WP_023610227.1\|539607_540372_+	(S)-acetoin forming diacetyl reductase	NA	NA	NA	NA
WP_109828714.1\|540479_542981_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	1.2e-204	48.2
541212:541229	attL	NA	NA	NA	NA
WP_002985439.1\|543316_544510_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002985437.1\|544530_545877_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_002985434.1\|546290_547181_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_111685698.1\|547177_548155_+	YvcK family protein	A1IMD5	Streptococcus_phage	5.6e-139	74.5
WP_011054317.1\|548151_549063_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.0e-105	64.7
WP_111685699.1\|549195_550593_+	C69 family dipeptidase	NA	NA	NA	NA
WP_020833384.1\|550733_552281_+	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_111685700.1\|552427_553150_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_111685701.1\|553169_554369_+	SIS domain-containing protein	NA	NA	NA	NA
WP_002985307.1\|554465_554726_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_002990475.1\|554840_555782_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985303.1\|556175_556625_+	flavodoxin	NA	NA	NA	NA
WP_010922101.1\|556808_557093_+	chorismate mutase	NA	NA	NA	NA
WP_109828710.1\|557085_558348_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	2.9e-95	51.0
WP_002985298.1\|558462_558810_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_111685702.1\|559173_560250_-\|integrase	site-specific integrase	Q0R5B4	Streptococcus_phage	2.0e-68	41.2
WP_023612337.1\|560368_560890_-	hypothetical protein	Q938N8	Temperate_phage	7.5e-66	97.7
WP_030126053.1\|560900_561278_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	1.6e-54	77.6
WP_023611288.1\|561261_561621_-	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.7e-56	95.0
WP_023612341.1\|561808_562027_+	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	5.9e-33	97.2
WP_023612302.1\|562126_562357_+	hypothetical protein	NA	NA	NA	NA
WP_164492191.1\|562340_562484_+	hypothetical protein	A0A1P8VVR9	Streptococcus_phage	3.4e-13	83.7
WP_023612348.1\|562493_562712_+	hypothetical protein	NA	NA	NA	NA
WP_003056170.1\|562713_562956_+	hypothetical protein	NA	NA	NA	NA
WP_023612340.1\|562942_564259_+	AAA family ATPase	A0A097BY67	Enterococcus_phage	7.8e-152	63.8
WP_003056188.1\|564273_565356_+	AAA family ATPase	A0A0K2CZH1	Paenibacillus_phage	2.5e-103	53.3
WP_003056185.1\|565550_566144_+	hypothetical protein	A0A097BY29	Enterococcus_phage	1.7e-29	43.5
WP_080262841.1\|566143_567727_+	DEAD/DEAH box helicase	A0A097BY72	Enterococcus_phage	2.0e-234	77.8
WP_023612331.1\|567739_567934_+	hypothetical protein	NA	NA	NA	NA
WP_023612365.1\|567956_570200_+	AAA family ATPase	Q5YA88	Bacillus_phage	4.7e-282	63.7
WP_003059078.1\|570491_570674_+	hypothetical protein	NA	NA	NA	NA
WP_111685703.1\|570666_571062_+	RusA family crossover junction endodeoxyribonuclease	Q5YA86	Bacillus_phage	4.8e-41	59.5
WP_010922069.1\|571058_571280_+	hypothetical protein	NA	NA	NA	NA
WP_111685704.1\|571282_571555_+	hypothetical protein	A7J287	Streptococcus_phage	1.2e-17	58.9
WP_011017571.1\|571558_572041_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_021299463.1\|572030_572795_+	site-specific DNA-methyltransferase	A0A1S5SE41	Streptococcus_phage	4.2e-134	92.3
WP_111685705.1\|572885_573179_+	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	1.5e-47	96.9
WP_003052405.1\|573634_574072_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	3.6e-77	100.0
WP_019418850.1\|574405_575572_+	ParB N-terminal domain-containing protein	Q708N6	Streptococcus_phage	7.9e-124	53.9
WP_010922073.1\|575914_576391_+	hypothetical protein	Q938L4	Temperate_phage	4.9e-48	68.4
WP_010922074.1\|576473_577685_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_010922075.1\|577698_579201_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.9e-281	99.6
WP_010922076.1\|579205_580699_+\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	2.1e-214	80.8
WP_010922077.1\|580698_580926_+	hypothetical protein	NA	NA	NA	NA
WP_010922078.1\|581012_581279_+	hypothetical protein	Q938K9	Temperate_phage	8.3e-37	95.5
WP_010922079.1\|581404_582019_+	hypothetical protein	Q938K8	Temperate_phage	3.1e-95	95.0
WP_010922080.1\|582022_582841_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_111685706.1\|582894_583311_+	hypothetical protein	Q938K7	Temperate_phage	2.8e-55	98.2
WP_111685707.1\|583300_583633_+\|capsid	minor capsid protein	Q79S86	Temperate_phage	1.1e-57	98.2
WP_010922083.1\|583632_583989_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_010922084.1\|583985_584384_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_011054741.1\|584383_584869_+	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_010922086.1\|584907_585342_+	hypothetical protein	Q938K5	Temperate_phage	2.9e-71	99.3
WP_010922087.1\|585345_585927_+	hypothetical protein	Q938K4	Temperate_phage	1.6e-104	98.4
WP_030126579.1\|585916_589177_+	tape measure protein	Q938K3	Temperate_phage	0.0e+00	98.6
WP_111685708.1\|589173_589890_+\|tail	phage tail family protein	Q938K2	Temperate_phage	5.5e-136	98.7
WP_021775334.1\|589886_592031_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	95.7
WP_111685709.1\|592027_593032_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	5.3e-108	62.7
WP_111685710.1\|593046_594933_+	gp58-like family protein	Q938J9	Temperate_phage	4.6e-222	86.5
WP_002987513.1\|594944_595376_+	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_032461328.1\|595378_595996_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.7e-77	88.8
WP_002987582.1\|596005_596281_+	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_000609113.1\|596277_596505_+\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_111685711.1\|596620_597823_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.8e-235	97.5
WP_032465096.1\|598189_598732_+	SocA family protein	Q938J3	Temperate_phage	2.2e-44	51.1
WP_032465095.1\|598735_599572_+	hypothetical protein	Q938J2	Temperate_phage	4.3e-63	52.3
WP_003055891.1\|599639_599996_-	hypothetical protein	NA	NA	NA	NA
WP_003055874.1\|599997_600471_-	hypothetical protein	A3F671	Streptococcus_phage	8.0e-83	94.3
WP_003055856.1\|600509_600749_-	hypothetical protein	NA	NA	NA	NA
WP_030127450.1\|600951_601131_+	hypothetical protein	A3F673	Streptococcus_phage	3.4e-18	77.6
WP_002994056.1\|601952_602522_+	hydrolase	NA	NA	NA	NA
WP_002994058.1\|602522_604475_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	8.9e-144	46.3
WP_002990455.1\|604831_606556_+	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_002990451.1\|606687_607146_-	YueI family protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
WP_002985288.1\|607378_608686_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
612722:612739	attR	NA	NA	NA	NA

DBSCAN-SWA_5

673697 : 684301

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050580611.1\|673697_675908_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.2
WP_023609837.1\|676015_677179_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	7.6e-143	64.9
WP_002985140.1\|677175_677862_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002990262.1\|677955_679122_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002992643.1\|679182_679524_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_002992646.1\|679744_681097_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	23.8
WP_002992648.1\|681176_682454_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_014407485.1\|682483_682924_-	membrane protein	NA	NA	NA	NA
WP_002985123.1\|683158_684301_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	4.1e-24	27.0

DBSCAN-SWA_6

985508 : 1064285

Streptococcus_phage(60.71%)

integrase,protease,head,terminase,tail,tRNA,holin,capsid,portal

attL 1018875:1018934|attR 1060824:1060919

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032465038.1\|985508_986393_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_023610008.1\|986508_987849_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_023609998.1\|987954_988911_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_002993908.1\|988921_989518_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_023610003.1\|989609_992246_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_002989664.1\|992260_992962_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
WP_002984482.1\|993079_993622_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|993764_994406_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002994467.1\|994568_995057_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984476.1\|995067_995268_-	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
WP_002984475.1\|995308_995848_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984473.1\|995860_996049_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_011106783.1\|996059_996671_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|996707_996956_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002989648.1\|997318_999637_-	DNA helicase PcrA	A7KV33	Bacillus_phage	3.5e-131	41.2
WP_038432363.1\|1000166_1001489_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_014635492.1\|1001608_1002844_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_009880829.1\|1003213_1003987_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_014635494.1\|1004356_1005193_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002992415.1\|1005208_1005838_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-28	35.5
WP_002992417.1\|1005847_1006489_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_111685758.1\|1006595_1006931_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002984451.1\|1007126_1008941_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.2e-98	38.9
WP_002984449.1\|1009116_1009674_-	signal peptidase I	NA	NA	NA	NA
WP_002984447.1\|1009891_1011394_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|1011456_1012470_-	6-phosphofructokinase	NA	NA	NA	NA
WP_002984441.1\|1012549_1015660_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	1.4e-119	29.8
WP_002989617.1\|1015844_1016216_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002992425.1\|1016215_1016914_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|1016923_1017709_+	hypothetical protein	NA	NA	NA	NA
WP_002989607.1\|1017839_1018454_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
1018875:1018934	attL	NA	NA	NA	NA
WP_011054546.1\|1019044_1019233_-	hypothetical protein	A3F673	Streptococcus_phage	1.2e-21	84.7
WP_020833516.1\|1019347_1020136_-	streptococcal pyrogenic exotoxin SpeL	Q938J1	Temperate_phage	1.2e-46	41.4
WP_014635497.1\|1020417_1021131_-	streptococcal pyrogenic exotoxin SpeM	Q938J1	Temperate_phage	9.0e-78	59.5
WP_111685759.1\|1021514_1022108_-	GNAT family N-acetyltransferase	A0A0A8WFI2	Clostridium_phage	2.4e-23	38.2
WP_111685760.1\|1022107_1022311_-	hypothetical protein	NA	NA	NA	NA
WP_002994484.1\|1023174_1023867_-	AP2 domain-containing protein	A0A2H4J2S8	uncultured_Caudovirales_phage	1.5e-32	34.2
WP_111685761.1\|1024099_1024657_-	glycoside hydrolase family 73 protein	A7J2B5	Streptococcus_phage	1.0e-92	85.9
WP_003058873.1\|1024772_1025000_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_002987582.1\|1024996_1025272_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_111685762.1\|1025281_1025899_-	hypothetical protein	A3F662	Streptococcus_phage	5.7e-81	90.2
WP_023079239.1\|1025901_1026330_-	DUF1617 family protein	A3F661	Streptococcus_phage	3.0e-68	92.9
WP_111685763.1\|1029271_1031416_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	94.0
WP_014411854.1\|1031412_1032120_-\|tail	phage tail family protein	Q938K2	Temperate_phage	1.7e-92	71.1
WP_111685764.1\|1032119_1036043_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.1e-249	50.0
WP_014411856.1\|1036055_1036223_-	hypothetical protein	J7KBS0	Streptococcus_phage	2.9e-19	87.3
WP_014411857.1\|1036252_1036579_-	hypothetical protein	J7KK85	Streptococcus_phage	6.0e-37	73.1
WP_014411858.1\|1036631_1037240_-\|tail	phage major tail protein	J7KKC8	Streptococcus_phage	2.3e-74	70.5
WP_002985347.1\|1037256_1037682_-	hypothetical protein	J7KBZ9	Streptococcus_phage	5.0e-68	85.1
WP_002985349.1\|1037678_1038056_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.4e-45	72.8
WP_063632712.1\|1038052_1038400_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	4.2e-49	84.5
WP_063631325.1\|1038396_1038699_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	4.7e-44	88.0
WP_023610889.1\|1038834_1040037_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	2.7e-135	64.7
WP_063631324.1\|1040062_1040728_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	2.3e-91	77.2
WP_063631323.1\|1040705_1041926_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	9.0e-187	81.9
WP_002985363.1\|1041959_1042184_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1042176_1042347_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_063632717.1\|1042343_1044098_-\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	95.9
WP_085577347.1\|1044101_1044332_-	hypothetical protein	NA	NA	NA	NA
WP_002985371.1\|1044334_1044802_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_063632710.1\|1044972_1045311_-	HNH endonuclease	J7KH36	Streptococcus_phage	2.4e-57	97.2
WP_011017866.1\|1045560_1046001_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_111685765.1\|1046273_1046909_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	3.0e-85	67.0
WP_111685766.1\|1047407_1047635_-	hypothetical protein	A3F630	Streptococcus_phage	4.3e-26	76.0
WP_111685768.1\|1048044_1048395_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.2e-45	87.5
WP_014635521.1\|1048348_1049218_-	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	5.8e-103	65.6
WP_011017876.1\|1049486_1051040_-	hypothetical protein	A0A1P8BM51	Lactococcus_phage	1.5e-210	70.6
WP_085577342.1\|1051057_1051540_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	1.7e-59	70.7
WP_085577341.1\|1051544_1052948_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.1
WP_014635524.1\|1052983_1053667_-	AAA family ATPase	J7KC09	Streptococcus_phage	4.6e-124	98.2
WP_011284877.1\|1053663_1053948_-	hypothetical protein	NA	NA	NA	NA
WP_002984315.1\|1053944_1054139_-	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_011284878.1\|1054138_1054468_-	hypothetical protein	J7KBZ0	Streptococcus_phage	7.9e-13	41.8
WP_011017881.1\|1054548_1054686_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_011017882.1\|1054682_1054979_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011054585.1\|1055057_1055243_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011284879.1\|1055409_1055649_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1055798_1056008_+	hypothetical protein	NA	NA	NA	NA
WP_021340169.1\|1056223_1056463_-	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	3.1e-35	97.5
WP_111685769.1\|1056512_1057019_+	hypothetical protein	NA	NA	NA	NA
WP_021340823.1\|1057015_1057162_-	hypothetical protein	NA	NA	NA	NA
WP_085577339.1\|1057218_1058004_+	hypothetical protein	A0A1S5S7L0	Streptococcus_phage	4.8e-48	57.4
WP_080465047.1\|1058137_1058296_-	hypothetical protein	J7KH24	Streptococcus_phage	3.4e-22	92.3
WP_021340822.1\|1058469_1059258_+	peptidase S24	A0A1S5SD15	Streptococcus_phage	2.9e-85	62.6
WP_011106738.1\|1059267_1059573_+	membrane protein	NA	NA	NA	NA
WP_023079773.1\|1059692_1060781_+\|integrase	site-specific integrase	Q38159	Streptococcus_phage	3.0e-202	98.6
WP_002989605.1\|1061143_1061764_+	DUF3862 domain-containing protein	NA	NA	NA	NA
1060824:1060919	attR	NA	NA	NA	NA
WP_002992581.1\|1062020_1064285_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7

DBSCAN-SWA_7

1093670 : 1153043

Enterococcus_phage(25.0%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172450120.1\|1093670_1095012_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.0e-62	48.7
WP_002992869.1\|1095312_1096185_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_111685772.1\|1096408_1097719_+	SLC13 family permease	NA	NA	NA	NA
WP_011284472.1\|1097796_1098090_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_111685773.1\|1098038_1098692_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	7.3e-26	38.5
WP_014635546.1\|1098731_1098845_+\|transposase	transposase	NA	NA	NA	NA
WP_011017915.1\|1098861_1099593_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011017916.1\|1099706_1100072_+	thioesterase family protein	NA	NA	NA	NA
WP_014407647.1\|1100191_1101412_-	MFS transporter	NA	NA	NA	NA
WP_002995506.1\|1101785_1103270_+	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_002984115.1\|1103374_1103776_-	PaaI family thioesterase	NA	NA	NA	NA
WP_111685774.1\|1104790_1106182_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	2.4e-260	98.7
WP_111685775.1\|1106230_1107682_-	LCP family protein	NA	NA	NA	NA
WP_002989310.1\|1107889_1108381_-	shikimate kinase	NA	NA	NA	NA
WP_002984103.1\|1108373_1109657_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_014407653.1\|1109767_1110733_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_011054629.1\|1110734_1111595_-	methionyl aminopeptidase	NA	NA	NA	NA
WP_002989302.1\|1111610_1112894_-	CBS domain-containing protein	NA	NA	NA	NA
WP_002984095.1\|1112902_1113445_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011054631.1\|1114608_1115868_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_111685776.1\|1116041_1117238_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.3e-139	65.9
WP_014635553.1\|1117773_1120131_-	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_002984078.1\|1120334_1121276_+	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_012560785.1\|1121250_1121454_-	DUF3272 domain-containing protein	NA	NA	NA	NA
WP_021733069.1\|1121549_1123220_-	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	5.1e-47	40.6
WP_009881127.1\|1123219_1123717_-	GAF domain-containing protein	NA	NA	NA	NA
WP_002992609.1\|1123861_1124671_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_002989257.1\|1124723_1124987_-	DUF1294 domain-containing protein	NA	NA	NA	NA
WP_002984060.1\|1125066_1125693_-	uridine kinase	A0A1V0SAA3	Catovirus	2.2e-35	39.7
WP_002989254.1\|1125790_1126876_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.6e-33	32.3
WP_020837316.1\|1126985_1128260_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011284931.1\|1128354_1129782_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_023609954.1\|1129966_1131700_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_002984031.1\|1131704_1131968_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_002989242.1\|1132360_1132579_+	redoxin NrdH	A0A249XUR7	Enterococcus_phage	1.1e-13	49.3
WP_038432376.1\|1132598_1134758_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	6.1e-263	63.4
WP_002987365.1\|1135090_1136050_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	3.7e-127	70.5
WP_142402474.1\|1136039_1137338_+	chloride channel protein	NA	NA	NA	NA
WP_002995750.1\|1138681_1139377_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002995753.1\|1139395_1140157_-	DUF3169 family protein	NA	NA	NA	NA
WP_002989220.1\|1140153_1140369_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002995756.1\|1140729_1143348_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.1e-61	34.1
WP_020837342.1\|1143734_1144790_-	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_002989211.1\|1144852_1145560_-	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.6e-08	27.2
WP_111685777.1\|1145625_1146822_-	OFA family MFS transporter	NA	NA	NA	NA
WP_002995768.1\|1147197_1149003_-	oligoendopeptidase F	NA	NA	NA	NA
WP_111685778.1\|1149015_1149978_-	competence protein CoiA	NA	NA	NA	NA
WP_002995774.1\|1150273_1150990_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_002995779.1\|1151108_1151813_-	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_002995782.1\|1152014_1153043_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA

DBSCAN-SWA_8

1177556 : 1217567

Streptococcus_phage(68.0%)

integrase,terminase,tail,holin,capsid,portal

attL 1179761:1179780|attR 1214940:1214959

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002994378.1\|1177556_1179419_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.4e-90	33.8
1179761:1179780	attL	NA	NA	NA	NA
WP_014635572.1\|1179949_1180132_-	hypothetical protein	A3F673	Streptococcus_phage	1.7e-20	80.0
WP_014635573.1\|1180371_1181130_+	DNase Mf2	NA	NA	NA	NA
WP_002985327.1\|1181240_1181948_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_014635574.1\|1182016_1183234_-	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	1.1e-163	60.1
WP_003058873.1\|1183352_1183580_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_011017397.1\|1183576_1183849_-	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_111685784.1\|1183860_1184493_-	hypothetical protein	Q938J7	Temperate_phage	1.2e-44	50.5
WP_011528780.1\|1184495_1184924_-	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	87.9
WP_011528781.1\|1184932_1186714_-	hypothetical protein	Q938J9	Temperate_phage	1.5e-65	40.2
WP_111685785.1\|1186728_1187742_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.7e-168	91.1
WP_168388764.1\|1187741_1189715_-\|tail	phage tail protein	M1PKG3	Streptococcus_phage	2.0e-98	49.6
WP_002992579.1\|1189696_1190392_-	hypothetical protein	A0A1B1P761	Bacillus_phage	4.7e-07	32.2
WP_111685787.1\|1190388_1192752_-	hypothetical protein	M1NRG5	Streptococcus_phage	2.5e-132	50.1
WP_011054678.1\|1192751_1193123_-	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.7e-35	62.4
WP_010922455.1\|1193137_1193401_-	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_011054679.1\|1193411_1194002_-	hypothetical protein	M1PKG8	Streptococcus_phage	1.1e-60	62.5
WP_000573598.1\|1194017_1194353_-	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_000032787.1\|1194353_1194590_-	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_011054681.1\|1194582_1194921_-	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_011054682.1\|1194880_1195303_-	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_010922460.1\|1195312_1195513_-	hypothetical protein	NA	NA	NA	NA
WP_011054683.1\|1195512_1196424_-\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	2.9e-113	67.0
WP_010922462.1\|1196448_1196910_-	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_011054685.1\|1196990_1198406_-\|terminase	terminase	A0A0B5A091	Streptococcus_phage	1.5e-212	74.0
WP_011106704.1\|1198487_1198703_-	hypothetical protein	M1IRA5	Streptococcus_phage	4.1e-26	72.4
WP_002986828.1\|1198704_1198971_-	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011054687.1\|1198963_1199116_-	hypothetical protein	NA	NA	NA	NA
WP_002994100.1\|1199192_1199417_-	hypothetical protein	NA	NA	NA	NA
WP_010922467.1\|1199422_1200916_-	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_010922468.1\|1200908_1202177_-\|portal	phage portal protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
WP_002994106.1\|1202173_1202530_-	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_011054690.1\|1202677_1203022_-	HNH endonuclease	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
WP_011528791.1\|1203129_1203549_-	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
WP_011054692.1\|1203624_1203876_-	hypothetical protein	M1PF60	Streptococcus_phage	1.6e-18	59.0
WP_011054693.1\|1203872_1204028_-	hypothetical protein	NA	NA	NA	NA
WP_011054694.1\|1204024_1204342_-	DUF1372 family protein	A1EAD7	Streptococcus_phage	9.0e-30	71.4
WP_011054695.1\|1204377_1204890_-	hypothetical protein	M1PFM2	Streptococcus_phage	1.7e-78	85.9
WP_011184741.1\|1204886_1205219_-	hypothetical protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
WP_011054697.1\|1205229_1206576_-	PcfJ domain-containing protein	A8ATM0	Listeria_phage	1.0e-122	49.4
WP_011054698.1\|1206572_1206968_-	hypothetical protein	A8ATL9	Listeria_phage	1.4e-19	52.3
WP_111685788.1\|1207332_1208130_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	4.1e-132	84.5
WP_000594115.1\|1208122_1208323_-	hypothetical protein	NA	NA	NA	NA
WP_011054700.1\|1208319_1209246_-	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_011528796.1\|1209248_1209578_-	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_002988357.1\|1209633_1209840_-	hypothetical protein	NA	NA	NA	NA
WP_002988354.1\|1209848_1209989_-	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
WP_010922205.1\|1209985_1210219_-	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_011017564.1\|1210199_1210586_-	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_010922477.1\|1211119_1211305_-	hypothetical protein	Q938N3	Temperate_phage	1.3e-20	83.6
WP_010922478.1\|1211306_1211618_-	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_010922479.1\|1211887_1212100_-	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922480.1\|1212301_1213057_+	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922481.1\|1213068_1213587_+	restriction endonuclease	E8ZDN5	Streptococcus_phage	9.2e-32	45.9
WP_003051793.1\|1213710_1214853_+\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_002983920.1\|1214941_1215217_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
1214940:1214959	attR	NA	NA	NA	NA
WP_002989129.1\|1215315_1215903_-	YpmS family protein	NA	NA	NA	NA
WP_002992620.1\|1215880_1216723_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002983913.1\|1216715_1217567_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7

DBSCAN-SWA_9

1686145 : 1798885

113

Streptococcus_phage(63.93%)

integrase,protease,head,terminase,tail,tRNA,holin,capsid,portal,bacteriocin

attL 1716475:1716500|attR 1748157:1748182

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_053308647.1\|1686145_1686451_-\|protease	Spi family protease inhibitor	NA	NA	NA	NA
WP_021733538.1\|1686452_1687649_-	cysteine proteinase exotoxin SpeB	NA	NA	NA	NA
WP_002982418.1\|1687920_1688091_-	hypothetical protein	NA	NA	NA	NA
WP_002982409.1\|1688589_1689432_+	transcriptional regulator	NA	NA	NA	NA
WP_010922721.1\|1689672_1690488_-	streptodornase B	A7J2B8	Streptococcus_phage	6.7e-29	33.3
WP_011527790.1\|1690851_1691361_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	4.2e-37	53.5
WP_011285237.1\|1691442_1692531_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_002991266.1\|1692587_1693256_-	fructose-6-phosphate aldolase	NA	NA	NA	NA
WP_111685846.1\|1693268_1695686_-	glycyl radical protein	Q66LZ4	Escherichia_phage	3.6e-09	52.8
WP_023610203.1\|1695896_1697201_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002992103.1\|1697210_1697519_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002992105.1\|1697546_1697867_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_111685847.1\|1698155_1699136_-	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_002991277.1\|1699151_1699898_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002992110.1\|1700023_1700797_+	glycyl-radical enzyme activating protein	A0A0U2DAM7	Escherichia_phage	3.8e-05	36.2
WP_002982348.1\|1701033_1701210_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002982344.1\|1701223_1701376_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_011106917.1\|1701424_1703761_-	penicillin-binding protein	NA	NA	NA	NA
WP_002982339.1\|1703799_1704180_-	RidA family protein	NA	NA	NA	NA
WP_002991284.1\|1704755_1705757_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	3.7e-05	26.6
WP_011055066.1\|1705845_1707486_-	hypothetical protein	NA	NA	NA	NA
WP_002991288.1\|1707732_1709232_+	C69 family dipeptidase	NA	NA	NA	NA
WP_002982320.1\|1710460_1712092_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.8e-153	55.1
WP_002991292.1\|1712127_1712418_-	co-chaperone GroES	NA	NA	NA	NA
WP_111685848.1\|1712595_1715040_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	5.4e-122	39.2
WP_002982312.1\|1715039_1715501_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_002991299.1\|1715696_1715900_-	cold-shock protein	Q9AZD3	Lactococcus_phage	6.1e-24	80.0
1716475:1716500	attL	NA	NA	NA	NA
WP_063629765.1\|1716498_1717569_-\|integrase	site-specific integrase	A0A1P8VVR7	Streptococcus_phage	9.6e-92	48.3
WP_111685849.1\|1717696_1717999_-	hypothetical protein	A0A1S5SAH9	Streptococcus_phage	1.5e-21	53.6
WP_063629763.1\|1717991_1718378_-	hypothetical protein	Q938N7	Temperate_phage	2.4e-37	61.6
WP_063629762.1\|1718381_1718732_-	helix-turn-helix transcriptional regulator	A0A1S5S8C4	Streptococcus_phage	8.1e-40	70.6
WP_111685850.1\|1719128_1719338_+	helix-turn-helix transcriptional regulator	A0A1P8VVQ4	Streptococcus_phage	3.0e-26	88.2
WP_063629760.1\|1719337_1719700_+	hypothetical protein	A0A1P8VVU1	Streptococcus_phage	6.6e-37	68.8
WP_063629759.1\|1719721_1720006_+	hypothetical protein	B3GVX8	Streptococcus_phage	3.5e-41	81.9
WP_063629758.1\|1720032_1720251_+	hypothetical protein	A0A1P8VVV1	Streptococcus_phage	3.9e-24	83.3
WP_111685851.1\|1720259_1721606_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	9.3e-209	83.7
WP_111685852.1\|1721592_1722339_+	conserved phage C-terminal domain-containing protein	A0A1P8VVR3	Streptococcus_phage	3.5e-133	96.0
WP_111685853.1\|1722339_1723161_+	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.1e-148	95.2
WP_063629755.1\|1723160_1723388_+	hypothetical protein	C5J991	Streptococcus_phage	1.3e-11	46.6
WP_168388561.1\|1723401_1723572_+	hypothetical protein	Q938M0	Temperate_phage	2.5e-10	96.8
WP_109982045.1\|1723568_1723838_+	hypothetical protein	A7J287	Streptococcus_phage	1.4e-28	77.5
WP_111685854.1\|1723840_1724590_+	site-specific DNA-methyltransferase	Q9MCL7	Streptococcus_virus	7.3e-131	89.5
WP_111685855.1\|1725395_1725614_+	hypothetical protein	NA	NA	NA	NA
WP_032460876.1\|1725610_1726003_+	single-stranded DNA-binding protein	A0A1P8VVS8	Streptococcus_phage	4.1e-48	71.7
WP_029713970.1\|1726016_1726295_+	hypothetical protein	A3F632	Streptococcus_phage	9.6e-44	96.7
WP_063629751.1\|1726389_1726617_+	hypothetical protein	NA	NA	NA	NA
WP_063629750.1\|1726588_1727053_+	hypothetical protein	A0A1P8VVT5	Streptococcus_phage	5.8e-78	92.2
WP_063629749.1\|1727162_1727705_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	8.3e-100	98.9
WP_063629748.1\|1727874_1728057_+	hypothetical protein	A0A1S5SAV8	Streptococcus_phage	6.5e-09	51.7
WP_111685856.1\|1728322_1728640_+	HNH endonuclease	A0A1S5SD32	Streptococcus_phage	6.4e-52	90.5
WP_000601034.1\|1728757_1729243_+	hypothetical protein	A0A1S5SCZ6	Streptococcus_phage	3.2e-79	98.1
WP_111685857.1\|1729235_1730948_+\|terminase	terminase large subunit	A0A1S5SCW2	Streptococcus_phage	0.0e+00	97.0
WP_111685858.1\|1730956_1732099_+\|portal	phage portal protein	A0A1P8VVT4	Streptococcus_phage	5.3e-213	98.2
WP_063629746.1\|1732149_1732692_+\|head,protease	HK97 family phage prohead protease	A0A1P8VVX2	Streptococcus_phage	6.8e-94	96.7
WP_063629745.1\|1732702_1733965_+\|capsid	phage major capsid protein	A0A1P8VVT0	Streptococcus_phage	5.8e-197	85.6
WP_032460894.1\|1733984_1734323_+	hypothetical protein	A0A1P8VVS7	Streptococcus_phage	1.2e-45	80.6
WP_032460893.1\|1734319_1734625_+\|head,tail	head-tail adaptor protein	A0A1P8VVX4	Streptococcus_phage	5.4e-40	84.2
WP_032460892.1\|1734624_1734972_+	hypothetical protein	A0A1P8VVS6	Streptococcus_phage	3.6e-56	92.2
WP_063629744.1\|1734958_1735303_+	hypothetical protein	A0A1P8VVU6	Streptococcus_phage	8.8e-55	92.1
WP_063629743.1\|1735317_1735989_+\|tail	phage tail protein	A0A1P8VVR1	Streptococcus_phage	7.6e-111	89.9
WP_063629742.1\|1735992_1736466_+	hypothetical protein	A0A0A0YX24	Streptococcus_phage	9.2e-79	90.4
WP_111685860.1\|1736655_1739391_+\|tail	phage tail tape measure protein	A0A1P8VVW8	Streptococcus_phage	4.7e-244	90.5
WP_063629740.1\|1739387_1740110_+	hypothetical protein	A0A1P8VVR4	Streptococcus_phage	1.7e-124	90.0
WP_111685880.1\|1740134_1742054_+\|tail	phage tail protein	A0A1P8VVT1	Streptococcus_phage	5.2e-181	64.6
WP_063629043.1\|1742050_1743166_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.7e-123	71.7
WP_111685861.1\|1743180_1744962_+	hypothetical protein	Q938J9	Temperate_phage	2.0e-73	42.8
WP_111685862.1\|1744970_1745399_+	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	89.3
WP_111685863.1\|1745401_1746040_+	hypothetical protein	A3F662	Streptococcus_phage	1.2e-44	53.2
WP_111685864.1\|1746049_1746322_+	hypothetical protein	A7J2B2	Streptococcus_phage	1.6e-35	89.9
WP_003058873.1\|1746318_1746546_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_111685865.1\|1746661_1747879_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	3.7e-164	60.1
WP_002982304.1\|1748756_1749317_+	peroxiredoxin	NA	NA	NA	NA
1748157:1748182	attR	NA	NA	NA	NA
WP_002982300.1\|1749337_1750870_+	alkyl hydroperoxide reductase subunit F	A0A2I2L5E1	Orpheovirus	1.4e-43	37.5
WP_002982296.1\|1750927_1752193_-	imidazolonepropionase	NA	NA	NA	NA
WP_020905558.1\|1752484_1754515_+	urocanate hydratase	NA	NA	NA	NA
WP_011055073.1\|1754602_1755502_+	glutamate formimidoyltransferase	NA	NA	NA	NA
WP_111685866.1\|1755512_1756139_+	cyclodeaminase/cyclohydrolase family protein	NA	NA	NA	NA
WP_093974938.1\|1756156_1757830_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_093974939.1\|1757851_1758448_+	HutD family protein	NA	NA	NA	NA
WP_093974941.1\|1758667_1760011_+	APC family permease	NA	NA	NA	NA
WP_111685867.1\|1760022_1761564_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	3.1e-99	43.9
WP_002982269.1\|1761749_1762736_+	arginase family protein	NA	NA	NA	NA
WP_093974943.1\|1762766_1765841_-	AAA family ATPase	NA	NA	NA	NA
WP_002982262.1\|1766144_1766912_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_010922743.1\|1767045_1768086_+	elongation factor Ts	NA	NA	NA	NA
WP_002992817.1\|1768251_1770147_-	M13 family metallopeptidase	A0A1V0SHG2	Klosneuvirus	5.2e-72	28.7
WP_023610271.1\|1770354_1771983_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_111685868.1\|1772050_1774075_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_111676868.1\|1774285_1774999_+	trehalose operon repressor	NA	NA	NA	NA
WP_076637095.1\|1775278_1775545_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_038432671.1\|1775802_1776660_+	VOC family protein	NA	NA	NA	NA
WP_002982222.1\|1776701_1777433_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	1.6e-34	37.0
WP_002982219.1\|1777606_1778221_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	1.5e-52	56.7
WP_002991345.1\|1778220_1778730_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_111685869.1\|1778738_1779674_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002982210.1\|1779702_1779849_-	hypothetical protein	NA	NA	NA	NA
WP_002992831.1\|1780030_1782229_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.6e-277	64.9
WP_030126183.1\|1782325_1783885_-	membrane protein	NA	NA	NA	NA
WP_002982199.1\|1784297_1784603_-	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_002982196.1\|1784614_1785034_-	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_002982194.1\|1785030_1785300_-	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_002982188.1\|1785414_1785813_-	transcriptional regulator Spx	NA	NA	NA	NA
WP_002992179.1\|1786103_1787240_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.4e-120	63.0
WP_002992182.1\|1787328_1788600_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_002992183.1\|1788668_1789229_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_038432673.1\|1789238_1789835_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_002992187.1\|1789836_1791057_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.5e-05	23.6
WP_002992189.1\|1791067_1793050_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
WP_002993100.1\|1793178_1795734_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	5.2e-43	23.3
WP_002982173.1\|1795720_1795927_-	hypothetical protein	NA	NA	NA	NA
WP_002993102.1\|1796069_1796507_-	arginine repressor	NA	NA	NA	NA
WP_002993104.1\|1796797_1798489_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.9e-73	32.4
WP_002993106.1\|1798576_1798885_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NZ_LS483352.1|WP_111685759.1|1021514_1022108_-|GNAT-family-N-acetyltransferase

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483352.1|WP_111685759.1|1021514_1022108_-|GNAT-family-N-acetyltransferase

1021514_1022108_-

197 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|89	0.46875	0.9695431472081218	0.9792746113989638

985508-1064285

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483352

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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