CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483351	Streptococcus pyogenes strain NCTC8195 chromosome 1	2 crisprs	DinG,csm6,cas3,DEDDh,csa3	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483351_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483351_1

1050449-1050550

Orphan

Consensus_repeat	Method
AATAATTGGTATAGTCTAATTATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483351_1

>merge|NZ_LS483351|1|1050449-1050550|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATACCGATAAAAACATTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACATAAAATTGGTATAGTCTAATTATA

>NZ_LS483351|1|1|1050449-1050550|CRISPRCasFinder
AATAATTGGTATAGTCTAATTATA	CCGATAAAAACATTATGTTTACAGTATATAATATCCACAATGTCTTGTCAAACA
TAAAATTGGTATAGTCTAATTATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483351.1\|WP_002984455.1\|1047304_1047946_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_LS483351.1\|WP_002984447.1\|1051348_1052851_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_LS483351.1\|WP_002984469.1\|1038167_1038416_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NZ_LS483351.1\|WP_002984465.1\|1041624_1042947_+\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NZ_LS483351.1\|WP_002984457.1\|1046665_1047295_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_LS483351.1\|WP_002984426.1\|1060501_1060690_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002984453.1\|1048052_1048388_-\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NZ_LS483351.1\|WP_032467272.1\|1057301_1057673_+\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NZ_LS483351.1\|WP_011285611.1\|1060927_1061728_+\|streptodornase-Sda3	unknown	unknown	gnl\|CDD\|372824
NZ_LS483351.1\|WP_002984444.1\|1052913_1053927_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NZ_LS483351.1\|WP_002984460.1\|1045813_1046650_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NZ_LS483351.1\|WP_002984467.1\|1038777_1041096_-\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NZ_LS483351.1\|WP_002984441.1\|1054006_1057117_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NZ_LS483351.1\|WP_002984451.1\|1048583_1050398_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NZ_LS483351.1\|WP_002989607.1\|1059296_1059911_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_LS483351.1\|WP_002984464.1\|1043066_1044302_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NZ_LS483351.1\|WP_002984437.1\|1057672_1058371_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NZ_LS483351.1\|WP_002984433.1\|1058380_1059166_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002984462.1\|1044671_1045445_-\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NZ_LS483351.1\|WP_002984449.1\|1050573_1051131_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044

Protein	Function_ID	Function_description	E-value
NZ_LS483351.1\|WP_002984455.1\|1047304_1047946_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.36474e-71
NZ_LS483351.1\|WP_002984447.1\|1051348_1052851_-\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_LS483351.1\|WP_002984469.1\|1038167_1038416_-\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NZ_LS483351.1\|WP_002984465.1\|1041624_1042947_+\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NZ_LS483351.1\|WP_002984457.1\|1046665_1047295_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.89978e-111
NZ_LS483351.1\|WP_002984453.1\|1048052_1048388_-\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	1.37463e-64
NZ_LS483351.1\|WP_032467272.1\|1057301_1057673_+\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	1.32055e-48
NZ_LS483351.1\|WP_011285611.1\|1060927_1061728_+\|streptodornase-Sda3	gnl\|CDD\|372824	pfam13930, Endonuclea_NS_2, DNA/RNA non-specific endonuclease.	7.11109e-26
NZ_LS483351.1\|WP_002984444.1\|1052913_1053927_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NZ_LS483351.1\|WP_002984460.1\|1045813_1046650_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.79673e-109
NZ_LS483351.1\|WP_002984467.1\|1038777_1041096_-\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NZ_LS483351.1\|WP_002984441.1\|1054006_1057117_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NZ_LS483351.1\|WP_002984451.1\|1048583_1050398_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NZ_LS483351.1\|WP_002989607.1\|1059296_1059911_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NZ_LS483351.1\|WP_002984464.1\|1043066_1044302_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	9.55614e-95
NZ_LS483351.1\|WP_002984437.1\|1057672_1058371_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
NZ_LS483351.1\|WP_002984462.1\|1044671_1045445_-\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	3.19117e-97
NZ_LS483351.1\|WP_002984449.1\|1050573_1051131_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38

>NZ_LS483351.1|WP_002984451.1|1048583_1050398_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NZ_LS483351.1|WP_002984453.1|1048052_1048388_-|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVVFDSNGVRLSDGDTITVIKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NZ_LS483351.1|WP_002984455.1|1047304_1047946_-|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKVPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NZ_LS483351.1|WP_002984457.1|1046665_1047295_-|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NZ_LS483351.1|WP_002984460.1|1045813_1046650_-|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKERQNKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NZ_LS483351.1|WP_002984462.1|1044671_1045445_-|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQANLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKSFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NZ_LS483351.1|WP_002984464.1|1043066_1044302_+|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSAAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKAEQLLSDQFSIYDIDIHVEPAMILEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQITPIAKRQLHHTHYRIVKM
>NZ_LS483351.1|WP_002984465.1|1041624_1042947_+|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NZ_LS483351.1|WP_002984467.1|1038777_1041096_-|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANSLGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NZ_LS483351.1|WP_002984469.1|1038167_1038416_-|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN
>NZ_LS483351.1|WP_002984449.1|1050573_1051131_-|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NZ_LS483351.1|WP_002984447.1|1051348_1052851_-|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NZ_LS483351.1|WP_002984444.1|1052913_1053927_-|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NZ_LS483351.1|WP_002984441.1|1054006_1057117_-|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NZ_LS483351.1|WP_032467272.1|1057301_1057673_+|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQYVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NZ_LS483351.1|WP_002984437.1|1057672_1058371_+|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NZ_LS483351.1|WP_002984433.1|1058380_1059166_+|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNINTSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NZ_LS483351.1|WP_002989607.1|1059296_1059911_-|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NZ_LS483351.1|WP_002984426.1|1060501_1060690_-|hypothetical-protein
MLTYDEFKQAIDRGYITGDTVMIVRKNGQIFDYVLPHEKVKNGEVVTEEIVEEVMVELDYIK
>NZ_LS483351.1|WP_011285611.1|1060927_1061728_+|streptodornase-Sda3
MSKSNRRTWQGLVVILIAILTTFTTSTVTAARKIRNFPDTTEILLGTKATETPGILPFTGSYQLVLGDLDNLQRPTFAHIQLKDQDEPNIKRKGLKFNPPGWHNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYYENRLDSWLALHPNFWLDYKVTPVYHKNELVPRQVVLQYVGIDENGDLLQIKLGSEKESVDNFGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNLETEEFEEAA

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Crispr_ID: NZ_LS483351_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483351_2

1439671-1439756

Orphan

Consensus_repeat	Method
TGTTTAATTGACGGGATGTCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483351_2

>merge|NZ_LS483351|2|1439671-1439756|CRISPRCasFinder
TGTTTAATTGACGGGATGTCATCGACCGTCTCATTAATCTTATTTTTTAGGTCATCAAACGACTGTTTAATCGACGGGATGTCATC

>NZ_LS483351|2|2|1439671-1439756|CRISPRCasFinder
TGTTTAATTGACGGGATGTCATC	GACCGTCTCATTAATCTTATTTTTTAGGTCATCAAACGAC
TGTTTAATCGACGGGATGTCATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483351.1\|WP_111690677.1\|1435971_1437990_-\|gp58-like-family-protein	unknown	unknown	gnl\|CDD\|369586
NZ_LS483351.1\|WP_002983431.1\|1448485_1448842_-\|phage-head-tail-connector-protein	unknown	unknown	gnl\|CDD\|377467
NZ_LS483351.1\|WP_000639437.1\|1448196_1448475_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983441.1\|1446883_1447483_-\|phage-major-tail-protein,-TP901-1-family	unknown	unknown	gnl\|CDD\|273986
NZ_LS483351.1\|WP_002983425.1\|1449753_1450323_-\|DUF4355-domain-containing-protein	unknown	unknown	gnl\|CDD\|372987
NZ_LS483351.1\|WP_002983475.1\|1434427_1434883_-\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|377457
NZ_LS483351.1\|WP_002983445.1\|1446066_1446300_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983481.1\|1431816_1431996_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983429.1\|1448853_1449741_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983443.1\|1446374_1446830_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|222837
NZ_LS483351.1\|WP_002983439.1\|1447494_1447854_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983479.1\|1432062_1432857_-\|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl\|CDD\|164869
NZ_LS483351.1\|WP_002983485.1\|1429703_1430861_-\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|237061
NZ_LS483351.1\|WP_002983424.1\|1450483_1450750_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983467.1\|1435528_1435960_-\|DUF1617-family-protein	unknown	unknown	gnl\|CDD\|285058
NZ_LS483351.1\|WP_002983470.1\|1434893_1435526_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483351.1\|WP_002983483.1\|1431035_1431572_-\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NZ_LS483351.1\|WP_002983477.1\|1433101_1434316_-\|glucosaminidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|283125
NZ_LS483351.1\|WP_111680780.1\|1438002_1439124_-\|hyaluronoglucosaminidase	unknown	unknown	gnl\|CDD\|369263
NZ_LS483351.1\|WP_002983449.1\|1441172_1442015_-\|phage-tail-family-protein	unknown	unknown	gnl\|CDD\|177320

Protein	Function_ID	Function_description	E-value
NZ_LS483351.1\|WP_111690677.1\|1435971_1437990_-\|gp58-like-family-protein	gnl\|CDD\|369586	pfam07902, Gp58, gp58-like protein. Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.	0
NZ_LS483351.1\|WP_002983431.1\|1448485_1448842_-\|phage-head-tail-connector-protein	gnl\|CDD\|377467	pfam05135, Phage_connect_1, Phage gp6-like head-tail connector protein. This family of proteins contain head-tail connector proteins related to gp6 from bacteriophage HK97. A structure of this protein shows similarity to gp15 a well characterized connector component of bacteriophage SPP1.	1.79605e-07
NZ_LS483351.1\|WP_002983441.1\|1446883_1447483_-\|phage-major-tail-protein,-TP901-1-family	gnl\|CDD\|273986	TIGR02126, Major_tail_protein., phage major tail protein, TP901-1 family. This family includes the members of pfam06199 but is broader. Characterized members are major tail proteins from various phage, including lactococcal temperate bacteriophage TP901-1. [Mobile and extrachromosomal element functions, Prophage functions].	5.72039e-41
NZ_LS483351.1\|WP_002983425.1\|1449753_1450323_-\|DUF4355-domain-containing-protein	gnl\|CDD\|372987	pfam14265, DUF4355, Domain of unknown function (DUF4355). This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 180 and 214 amino acids in length.	9.49074e-14
NZ_LS483351.1\|WP_002983475.1\|1434427_1434883_-\|phage-holin-family-protein	gnl\|CDD\|377457	pfam05105, Phage_holin_4_1, Bacteriophage holin family. Phage holins and lytic enzymes are both necessary for bacterial lysis and virus dissemination. This family also includes TcdE/UtxA involved in toxin secretion in Clostridium difficile. The 1.E.10 family is represented by Bacillus subtilis phi29 holin; 1.E.16 represents the Cph1 holin; and the 1.E.19 family is represented by the Clostridium difficile TcdE holin. Toxigenic strains of C. difficile produce two large toxins (TcdA and TcdB) encoded within a pathogenicity locus. tcdE, encoded between tcdA and tcdB, encodes a 166 aa protein which causes death to E. coli when expressed, and the structure of TcdE resembles holins. TcdE acts on the bacterial membrane. Since TcdA and TcdB lack signal peptides, they may be released via TcdE either prior to or subsequent to cell lysis.	4.28603e-20
NZ_LS483351.1\|WP_002983443.1\|1446374_1446830_-\|hypothetical-protein	gnl\|CDD\|222837	PHA01794, PHA01794, hypothetical protein.	7.09783e-52
NZ_LS483351.1\|WP_002983479.1\|1432062_1432857_-\|DNA/RNA-non-specific-endonuclease	gnl\|CDD\|164869	PHA01790, PHA01790, streptodornase.	7.71061e-29
NZ_LS483351.1\|WP_002983485.1\|1429703_1430861_-\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
NZ_LS483351.1\|WP_002983467.1\|1435528_1435960_-\|DUF1617-family-protein	gnl\|CDD\|285058	pfam07761, DUF1617, Protein of unknown function (DUF1617). This is a family of sequences from hypothetical bacterial and bacteriophage proteins. The region in question is approximately 150 residues long and is highly conserved throughout the family.	9.12496e-73
NZ_LS483351.1\|WP_002983483.1\|1431035_1431572_-\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	7.13164e-51
NZ_LS483351.1\|WP_002983477.1\|1433101_1434316_-\|glucosaminidase-domain-containing-protein	gnl\|CDD\|283125	pfam05382, Amidase_5, Bacteriophage peptidoglycan hydrolase. At least one of the members of this family, the Pal protein from the pneumococcal bacteriophage Dp-1 has been shown to be a N-acetylmuramoyl-L-alanine amidase. According to the known modular structure of this and other peptidoglycan hydrolases from the pneumococcal system, the active site should reside at the N-terminal domain whereas the C-terminal domain binds to the choline residues of the cell wall teichoic acids. This family appears to be related to pfam00877.	3.72797e-66
NZ_LS483351.1\|WP_111680780.1\|1438002_1439124_-\|hyaluronoglucosaminidase	gnl\|CDD\|369263	pfam07212, Hyaluronidase_1, Hyaluronidase protein (HylP). This family consists of several phage associated hyaluronidase proteins (EC:3.2.1.35) which seem to be specific to Streptococcus pyogenes and Streptococcus pyogenes bacteriophages. The substrate of hyaluronidase is hyaluronic acid, a sugar polymer composed of alternating N-acetylglucosamine and glucuronic acid residues. Hyaluronic acid is found in the ground substance of human connective tissue and the vitreous of the eye and also is the sole component of the capsule of group A streptococci. The capsule has been shown to be an important virulence factor of this organism by virtue of its ability to resist phagocytosis. Production by S. pyogenes of both a hyaluronic acid capsule and hyaluronidase enzymatic activity capable of destroying the capsule is an interesting, yet-unexplained, phenomenon.	1.48265e-159
NZ_LS483351.1\|WP_002983449.1\|1441172_1442015_-\|phage-tail-family-protein	gnl\|CDD\|177320	PHA01795, PHA01795, hypothetical protein.	6.84658e-176

>NZ_LS483351.1|WP_111680780.1|1438002_1439124_-|hyaluronoglucosaminidase
MAENIPLRVQFKRMKAAEWARSNVVLLEGEIGFETDTGFAKFGDGQNTFSKLKYLTGPKGPKGDTGLQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQKEETNSKITKLESSKADKNAVYLKAESNAKLDEKLSLTGGIVTGQLQFKPNSGIKPSSSVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFNQSVQFVDYKGTTNAVNIVMRQPTTPNFSSALNITSANQGGSAMQIRGIERKLGTLKITHENPSVEADYDEDAAALSIDIVKKQEGGGNGTAAQGIYINSTSGTTGKLLRIRNLNDDKFYVNPDGGFYAKETSQIDGNLKLKDPIANDHAATKAYVDGEVEKLKALLTAKQM
>NZ_LS483351.1|WP_111690677.1|1435971_1437990_-|gp58-like-family-protein
MSRDPTLTLDESNLTIGSDGRAYYTFTADDNTKSVKIANDKCIGTTRFNQLMIERGDKPTNYVAPVVVEGTGNPTGLFKDLKELNLELTDTANSQLWAKIKLNNHGMLQTYFDTTIKNEILTTARGIRETISDTERGLKSEFLKTVQGQRIQLESLLEQKTAQLGLTVDGLRLDLNKAGKQTASLQASIEGLRQDYKDADRKLSSSYQAGIEGLKAAMRDDKLGLQSEIQATARGLSQEYDDKLHQLSAKIKTTSSGTTEAYENKLEGLRAEFTRSNQGMRVELESKISGLQSTQQATARQISQEISNREGAVSRVQQDLESYQRRLQDAEDNYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSIISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFTTKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKVIKARNGAMLIDLSSAKMDFNSNATINFNSRDNALVRRDDTHTAFVHFSNATPKGYTGSALYAAIGITSSGDGVNSASSGRFAGMRCFRHATGYNHTAAVDQTEIYGDSVLIADDFSINRGFKFRPDKMTKVLDMNDLYAAVVALGRCWKHLTNVGWNTAHSNFTNAVTNELNNHINKI
>NZ_LS483351.1|WP_002983467.1|1435528_1435960_-|DUF1617-family-protein
MDLTLKNKELNTLYRVLDKIKITNMRANRGRAKLLAKVVDKINEYAKDETDLIDMYAAKDKDDKFVIDEHKNIKLADPAKLDELNDLLNELADEEIVIKGGEYSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGE
>NZ_LS483351.1|WP_002983470.1|1434893_1435526_-|hypothetical-protein
MKTLTLSGKPYPIHEDGKVVKTEVRLIGDNGLFIPIELIGDQTAKGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQAKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKQGEYQAYDVFTVVDESHEDQAGEGNLVFVHVNEPFTYEAQTIEDLESEDKVTVIKYADLVKQD
>NZ_LS483351.1|WP_002983475.1|1434427_1434883_-|phage-holin-family-protein
MIIDLTSLIHLFGDLIRTVEIHVFTLFVCFDIITGLTKGITNKRANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQLGLPMPSFVRAFFEKLKRDTDQFDIATIKIDKTGVKLEAPQVDLKQKEEE
>NZ_LS483351.1|WP_002983477.1|1433101_1434316_-|glucosaminidase-domain-containing-protein
MTVDTEKAIAWMGLKEGRVSYSMDYRNGPDSYDCSSAICSALIYAGASNPGWLLNTEYMHDWLVQNGFELIAENEDWDSQRADIAIWGLRGQSAGAGGHVVMFIDADNIIHCNYANNNITIDNYNQTAAASGWMYSYAYRYNGEQSQPTNKSIDELAQEVLAGKHGSGEQRKLSLGSNYDAVQAKVNEMLKQPQVAEQSPAVKQDGDLLFNGAVLKKAILDKILAKCKEHDILPSYAITVLHFEGLWGQSAVGRADNNWGGMTWTGQGNRPSGITVTQGTERPAVEGGHYMHYASVDDFLTDWFYLLRADGSYRISGAKTFSEAVKGMFKVGGATYDYAASGYDNYIVGMSSRLKAIEQENGPINKYDQQTDISVGQSDKIDVVIDSIEITINGVTYTATKKPI
>NZ_LS483351.1|WP_002983479.1|1432062_1432857_-|DNA/RNA-non-specific-endonuclease
MNNIRLRKFISSIFLILLISSPISLSYQQATLADTKEVNVANRYNSSDTYLPEALSWTLETSPNYYKVLGESGIVENLFPPKGQIVYGGLDSLGRTLTVRGTLTFNNVLGSYNIRKDFKRSKAETLSGWLGNKNGEVYVIKGLGDDSYQGYFWNKSHLIADSLGGDALRVNAITGTRTQNVGGRSGNGGMRYTEIKSQKWLEAHRDGYLYYEAMPIYQGNELVPRAVVVSVLSSDNTINEKVIVYNVANGYTIDYNQGTFSANQ
>NZ_LS483351.1|WP_002983481.1|1431816_1431996_-|hypothetical-protein
MLTYDEFKQAIDRGYIVEDTVTIVRKNGQIFDYVLPHEKVKNGEVVTDEKVEEVLMELE
>NZ_LS483351.1|WP_002983483.1|1431035_1431572_-|ribosome-maturation-factor-RimP
MDSQEPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYELVDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSSPGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHKIVNIPYQAVAKVRMAVKL
>NZ_LS483351.1|WP_002983485.1|1429703_1430861_-|transcription-termination/antitermination-protein-NusA
MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSESCVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEFGRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQLSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDGTVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGLEIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGRRGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV
>NZ_LS483351.1|WP_002983449.1|1441172_1442015_-|phage-tail-family-protein
MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGYIYDGATFTTKTLKVKGRVTVSDVEGLLDKQDELNALLVVDEPFYVTKMYPENSDLFNFELPGESTGDLQLIGSPHKPWKYRFKVILDDTINYEFIGKTSQGLKYNLSFTLRTAELPFGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQNSQLQNSDKLLLTGISTTLNGNYINAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFVELYK
>NZ_LS483351.1|WP_002983445.1|1446066_1446300_-|hypothetical-protein
MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLTIKRSYQKASRSQADSDSSIVERIQMLNNHFQNR
>NZ_LS483351.1|WP_002983443.1|1446374_1446830_-|hypothetical-protein
MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGALFFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMVDSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS
>NZ_LS483351.1|WP_002983441.1|1446883_1447483_-|phage-major-tail-protein,-TP901-1-family
MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYRTDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIKIWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIVGALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK
>NZ_LS483351.1|WP_002983439.1|1447494_1447854_-|hypothetical-protein
MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNISDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNSIGREVYRVAINITETLF
>NZ_LS483351.1|WP_000639437.1|1448196_1448475_-|hypothetical-protein
MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQMGLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV
>NZ_LS483351.1|WP_002983431.1|1448485_1448842_-|phage-head-tail-connector-protein
MGDKQLIDDIKLFIGISKGDGAQDELITLAISESKERVLAKLNEYSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRSAAIGKVYSGKGVARFI
>NZ_LS483351.1|WP_002983429.1|1448853_1449741_-|hypothetical-protein
MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLTNDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHGAARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFEGSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYSTAVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEIPEGVVEATIEAAAVPGIGG
>NZ_LS483351.1|WP_002983425.1|1449753_1450323_-|DUF4355-domain-containing-protein
MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAERTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIETHSLLVEKGLPLDFIDIVLATTAEEVKTNIDNLQTIFDKAVEKRVNDRLTQKPPRTGNGSVGMTKADIMAIEDDDERMRLIAENRNLF
>NZ_LS483351.1|WP_002983424.1|1450483_1450750_-|hypothetical-protein
MNKRIKKKRKLETAIVMLVSENAMHAEAIKNQNRQIAELRAIIQQNAQATNNELAAIKGVGFDNQAAITNVAIDVNYIKKNYKRKWGK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36637 : 48952

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002986708.1\|36637_40363_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.6e-40	27.0
WP_002986705.1\|40523_41978_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.3e-54	33.3
WP_002986701.1\|42005_43028_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	6.9e-63	41.4
WP_002986700.1\|43195_43750_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.4e-25	36.1
WP_002986697.1\|43933_45481_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	9.8e-45	52.4
WP_002986694.1\|45539_46664_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_032467308.1\|46916_48182_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002986689.1\|48460_48952_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.9e-18	42.3

DBSCAN-SWA_2

159421 : 241225

Streptococcus_phage(41.67%)

capsid,terminase,tail,holin,portal,head,protease,integrase,tRNA

attL 177694:177711|attR 222267:222284

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002986372.1\|159421_161923_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	65.7
WP_002986370.1\|162229_163663_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002986367.1\|163733_164012_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002986362.1\|164134_164620_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002986359.1\|164710_165373_+	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	NA	NA	NA	NA
WP_002987909.1\|165377_166241_+	L-ribulose-5-phosphate 3-epimerase	NA	NA	NA	NA
WP_002986353.1\|166242_166947_+	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_002986350.1\|167271_168918_+	transcription antiterminator	NA	NA	NA	NA
WP_002986347.1\|169170_170262_+	L-ascorbate 6-phosphate lactonase	NA	NA	NA	NA
WP_002986345.1\|170750_171947_+	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.0e-30	39.2
WP_002986341.1\|171962_173690_+	ABC transporter permease/substrate binding protein	NA	NA	NA	NA
WP_002986338.1\|173820_176463_+	DNA polymerase I	A0A142F1Q9	Bacillus_phage	2.5e-64	35.9
WP_002986334.1\|176649_177105_+	CoA-binding protein	NA	NA	NA	NA
WP_002986328.1\|177156_177624_+	peroxide-responsive transcriptional repressor PerR	NA	NA	NA	NA
177694:177711	attL	NA	NA	NA	NA
WP_002986324.1\|177726_178590_-	DUF975 family protein	NA	NA	NA	NA
WP_002986319.1\|178808_179951_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.9e-86	43.9
WP_002986316.1\|180168_180480_+	hypothetical protein	NA	NA	NA	NA
WP_002986314.1\|180483_181023_+	biotin transporter BioY	NA	NA	NA	NA
WP_002986311.1\|181162_181942_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_002992549.1\|181941_182457_+	nucleoside deaminase	NA	NA	NA	NA
WP_002986305.1\|183070_184303_-	S-layer protein/peptidoglycan endo-beta-N-acetylglucosaminidase	NA	NA	NA	NA
WP_002986298.1\|184678_185380_-\|integrase	site-specific integrase	A0A141E0H2	Streptococcus_phage	4.1e-83	65.8
WP_002986291.1\|185947_186481_-	hypothetical protein	A0A1S5SAH9	Streptococcus_phage	1.3e-20	55.3
WP_002986288.1\|186492_186873_-	hypothetical protein	Q938N7	Temperate_phage	1.4e-40	64.0
WP_032467305.1\|186882_187233_-	helix-turn-helix transcriptional regulator	A0A1S5SFC6	Streptococcus_phage	4.8e-32	60.3
WP_002986282.1\|187543_187759_+	hypothetical protein	M1Q1B4	Streptococcus_phage	2.2e-24	78.6
WP_002986270.1\|187963_188707_+	ORF6C domain-containing protein	A3F617	Streptococcus_phage	1.5e-120	86.1
WP_002986266.1\|188782_188995_+	hypothetical protein	NA	NA	NA	NA
WP_002986264.1\|189028_189220_+	hypothetical protein	NA	NA	NA	NA
WP_002986261.1\|189251_189407_+	hypothetical protein	NA	NA	NA	NA
WP_002986259.1\|189408_189951_-	hypothetical protein	NA	NA	NA	NA
WP_002986256.1\|190081_190342_+	hypothetical protein	A0A1S5SAL2	Streptococcus_phage	1.1e-28	73.3
WP_002986254.1\|190360_190549_+	hypothetical protein	NA	NA	NA	NA
WP_002986252.1\|190535_191882_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	7.8e-208	84.7
WP_002986249.1\|191868_192471_+	hypothetical protein	A0A1P8VVT8	Streptococcus_phage	1.7e-106	93.0
WP_002986245.1\|192448_193195_+	conserved phage C-terminal domain-containing protein	A0A1P8VVR3	Streptococcus_phage	2.2e-135	96.8
WP_002986242.1\|193195_194020_+	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.4e-127	79.6
WP_002986238.1\|194019_194247_+	hypothetical protein	C5J991	Streptococcus_phage	7.1e-13	50.7
WP_032467330.1\|194260_194437_+	hypothetical protein	NA	NA	NA	NA
WP_002986233.1\|194433_194718_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	5.9e-41	93.6
WP_172450335.1\|194720_195359_+	DNA (cytosine-5-)-methyltransferase	A0A140HLV8	Bacillus_phage	1.7e-64	65.1
WP_002986227.1\|195346_195502_+	hypothetical protein	A0A1S5SFL7	Streptococcus_phage	1.6e-08	60.5
WP_002986215.1\|196528_196861_+	hypothetical protein	A0A1S5SCX1	Streptococcus_phage	1.2e-32	57.4
WP_002986212.1\|196853_197183_+	helix-turn-helix transcriptional regulator	A0A1P8VVV5	Streptococcus_phage	3.2e-22	45.5
WP_002986209.1\|197179_197353_+	hypothetical protein	A0A1J0MGB9	Staphylococcus_phage	1.1e-05	46.9
WP_002986206.1\|197355_197604_+	hypothetical protein	NA	NA	NA	NA
WP_002986201.1\|197788_197938_+	hypothetical protein	NA	NA	NA	NA
WP_002986198.1\|197906_198107_+	hypothetical protein	NA	NA	NA	NA
WP_002986196.1\|198130_198550_+	sigma-70 family RNA polymerase sigma factor	A0A1S5SF97	Streptococcus_phage	1.1e-19	42.0
WP_032467304.1\|198644_199208_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	5.4e-62	61.5
WP_002986191.1\|199379_199673_+	hypothetical protein	NA	NA	NA	NA
WP_002986189.1\|199669_199999_+	HNH endonuclease	A0A1S7FZ53	Listeria_phage	6.7e-20	49.5
WP_002986187.1\|200120_200468_+	hypothetical protein	E2ELI1	Clostridium_phage	4.0e-07	34.5
WP_002986185.1\|200448_202107_+\|terminase	terminase large subunit	E2ELI2	Clostridium_phage	4.0e-129	44.4
WP_002986182.1\|202305_203541_+\|portal	phage portal protein	A0A1S7FYX7	Listeria_phage	3.6e-74	37.6
WP_002986180.1\|203544_204261_+\|protease	Clp protease ClpP	D2XR17	Bacillus_phage	1.4e-38	42.9
WP_002986177.1\|204296_205490_+\|capsid	phage major capsid protein	A0A1B1P752	Bacillus_phage	1.7e-41	30.8
WP_002986176.1\|205504_205792_+	hypothetical protein	NA	NA	NA	NA
WP_002986174.1\|205811_206105_+\|head,tail	phage gp6-like head-tail connector protein	NA	NA	NA	NA
WP_111680753.1\|206106_206484_+\|head,tail	phage head-tail adapter protein	NA	NA	NA	NA
WP_002986170.1\|206455_206827_+	hypothetical protein	NA	NA	NA	NA
WP_002986168.1\|206835_207258_+	hypothetical protein	A0A1S7FZ20	Listeria_phage	3.1e-25	48.5
WP_002986166.1\|207268_207856_+	hypothetical protein	A0A1B1P778	Bacillus_phage	1.1e-28	36.4
WP_002986164.1\|207876_208248_+	hypothetical protein	NA	NA	NA	NA
WP_002986162.1\|208283_208442_+	hypothetical protein	NA	NA	NA	NA
WP_002986160.1\|208515_211917_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	9.5e-93	58.8
WP_111680754.1\|211916_212624_+\|tail	phage tail family protein	A0A1B1P761	Bacillus_phage	1.3e-28	35.2
WP_002986155.1\|212620_214669_+\|tail	phage tail protein	Q938K1	Temperate_phage	2.2e-121	44.0
WP_111690640.1\|214668_215685_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	3.3e-158	87.0
WP_111680756.1\|215700_217716_+	gp58-like family protein	Q938J9	Temperate_phage	3.4e-183	75.0
WP_002987513.1\|217727_218159_+	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_111680757.1\|218161_218779_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	2.8e-80	90.2
WP_002986151.1\|218788_219244_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	8.9e-63	80.8
WP_002986150.1\|219355_220561_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	3.1e-208	84.5
WP_032467302.1\|220676_221849_-	streptodornase Sda1	A7J2B8	Streptococcus_phage	1.4e-75	49.5
WP_002986147.1\|222087_222270_+	hypothetical protein	A3F673	Streptococcus_phage	1.1e-19	80.0
WP_002986145.1\|222319_222511_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
222267:222284	attR	NA	NA	NA	NA
WP_002986141.1\|223183_223888_+	streptococcal pyrogenic exotoxin SpeG	NA	NA	NA	NA
WP_002986136.1\|224343_225693_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_002986134.1\|226040_227549_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002986126.1\|228236_228908_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_002986125.1\|229006_229906_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	9.6e-77	52.2
WP_002986123.1\|229938_230955_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002986120.1\|231252_231702_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_002986117.1\|231694_233401_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.1e-36	26.9
WP_002986115.1\|233403_235188_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.3e-44	28.1
WP_002986113.1\|235305_236073_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_002986111.1\|236182_236629_+	dUTP diphosphatase	A0A1P8BLJ0	Lactococcus_phage	4.5e-35	52.8
WP_002986109.1\|236709_238071_+	DNA repair protein RadA	NA	NA	NA	NA
WP_002986108.1\|238259_238757_+	carbonic anhydrase	NA	NA	NA	NA
WP_002986107.1\|238887_239598_+	TIGR00266 family protein	NA	NA	NA	NA
WP_002986105.1\|239779_241225_+\|tRNA	glutamate--tRNA ligase	A0A2K9L481	Tupanvirus	6.8e-08	31.2

DBSCAN-SWA_3

364457 : 421747

Streptococcus_phage(33.33%)

transposase,tRNA,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985850.1\|364457_365048_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7
WP_002985847.1\|365542_365818_+	YlbG family protein	NA	NA	NA	NA
WP_032464192.1\|366066_366702_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.2e-65	63.4
WP_002985844.1\|366719_367595_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.1e-68	46.6
WP_032467296.1\|367613_367853_+	Tpl protein	NA	NA	NA	NA
WP_002985838.1\|368256_368580_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_002985836.1\|368584_369448_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
WP_002985833.1\|369474_369867_+	hypothetical protein	NA	NA	NA	NA
WP_002985831.1\|369913_370543_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002985829.1\|370840_371197_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.8e-40	66.7
WP_002985828.1\|371270_372098_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	8.4e-128	79.5
WP_002985826.1\|372331_373513_+	L-lactate oxidase	NA	NA	NA	NA
WP_002985822.1\|373778_378722_+\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_002985820.1\|379494_380202_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_002985818.1\|380441_382442_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	2.7e-87	35.3
WP_002985814.1\|382935_383949_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	1.6e-96	53.0
WP_002985812.1\|383952_384441_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_002985810.1\|384407_386588_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	7.3e-171	43.2
WP_002985808.1\|386790_387543_-	ADP-ribosyltransferase	NA	NA	NA	NA
WP_002985807.1\|388000_388351_+	hypothetical protein	NA	NA	NA	NA
WP_032467294.1\|388765_389017_+	hypothetical protein	NA	NA	NA	NA
WP_002990844.1\|389994_390231_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_002985800.1\|390223_390922_+	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	5.4e-11	26.0
WP_032467293.1\|390997_391957_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002985796.1\|392289_393627_+	MFS transporter	NA	NA	NA	NA
WP_020833305.1\|393800_395183_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	6.5e-32	36.0
WP_002985793.1\|395216_395771_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002985791.1\|395770_396022_+	hypothetical protein	NA	NA	NA	NA
WP_002985789.1\|396041_396737_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002985787.1\|396887_397229_+	hypothetical protein	NA	NA	NA	NA
WP_002985785.1\|397327_397975_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_014407368.1\|398120_399053_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985780.1\|399116_399842_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_002985777.1\|399842_400697_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002985776.1\|400843_401650_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_002985774.1\|401866_404272_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.2e-88	51.4
WP_010921962.1\|404341_404695_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_002987482.1\|404917_406051_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_002990800.1\|406264_406690_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002985768.1\|406795_407485_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002985765.1\|407806_408535_+	UMP kinase	NA	NA	NA	NA
WP_002985763.1\|408563_409121_+	ribosome recycling factor	NA	NA	NA	NA
WP_002985761.1\|409229_410087_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985759.1\|410159_410669_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_002985757.1\|410665_410881_+	YozE family protein	NA	NA	NA	NA
WP_002985755.1\|411036_412218_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	2.1e-15	39.6
WP_032464218.1\|412532_414305_+	oleate hydratase	NA	NA	NA	NA
WP_002985751.1\|414463_415516_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_002985750.1\|415561_416137_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985748.1\|416295_416793_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002985746.1\|416773_417181_+	diacylglycerol kinase	NA	NA	NA	NA
WP_002985743.1\|417300_418197_+	GTPase Era	NA	NA	NA	NA
WP_002985741.1\|418217_418694_+	NUDIX hydrolase	NA	NA	NA	NA
WP_002987564.1\|419899_420082_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|421306_421534_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002985729.1\|421546_421747_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA

DBSCAN-SWA_4

507291 : 549943

Streptococcus_phage(63.64%)

capsid,terminase,holin,portal,tail,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985544.1\|507291_508785_-\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	2.5e-90	40.7
WP_002985542.1\|508958_509861_+	HAD family hydrolase	NA	NA	NA	NA
WP_002985540.1\|509995_510592_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_002985539.1\|510932_511412_-\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
WP_002993643.1\|511501_512065_-	energy-coupled thiamine transporter ThiT	NA	NA	NA	NA
WP_002985536.1\|512333_513182_-	glycoside hydrolase family 25 protein	A0A223LJI5	Bacillus_phage	1.9e-18	31.3
WP_002985534.1\|513506_514010_+	ECF transporter S component	NA	NA	NA	NA
WP_002985532.1\|513993_514377_+	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_111690646.1\|514727_516185_-	recombinase family protein	Q38184	Lactococcus_phage	1.5e-132	50.7
WP_111690647.1\|516320_516839_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	7.8e-31	45.3
WP_111676607.1\|516850_517606_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	3.3e-78	61.2
WP_010922479.1\|517807_518020_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_011889039.1\|518188_518371_-	hypothetical protein	NA	NA	NA	NA
WP_111690648.1\|518603_518789_+	hypothetical protein	Q938N3	Temperate_phage	1.1e-22	91.8
WP_111678999.1\|519277_519667_+	DnaD domain protein	Q938N2	Temperate_phage	8.7e-51	77.5
WP_002985387.1\|519647_519881_+	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_011017992.1\|519877_520018_+	hypothetical protein	NA	NA	NA	NA
WP_011017565.1\|520026_520233_+	hypothetical protein	NA	NA	NA	NA
WP_011528796.1\|520288_520618_+	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_011054700.1\|520620_521547_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_000594115.1\|521543_521744_+	hypothetical protein	NA	NA	NA	NA
WP_011054699.1\|521736_522534_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	1.3e-130	83.8
WP_111690649.1\|522897_523293_+	hypothetical protein	A8ATL9	Listeria_phage	2.6e-18	51.1
WP_011054697.1\|523289_524636_+	PcfJ domain-containing protein	A8ATM0	Listeria_phage	1.0e-122	49.4
WP_011184741.1\|524646_524979_+	hypothetical protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
WP_111690650.1\|524975_525488_+	hypothetical protein	M1PFM2	Streptococcus_phage	5.8e-79	86.5
WP_111690651.1\|525523_525838_+	DUF1372 family protein	A1EAD7	Streptococcus_phage	4.4e-29	71.1
WP_111690652.1\|525839_526055_+	hypothetical protein	NA	NA	NA	NA
WP_111690653.1\|526051_526303_+	hypothetical protein	M1PF60	Streptococcus_phage	4.8e-18	57.8
WP_011528791.1\|526378_526798_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
WP_111690654.1\|526905_527250_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
WP_002994106.1\|527398_527755_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_010922468.1\|527751_529020_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
WP_111690655.1\|529012_530506_+	hypothetical protein	M1Q184	Streptococcus_phage	2.6e-87	54.6
WP_002994100.1\|530511_530736_+	hypothetical protein	NA	NA	NA	NA
WP_011054687.1\|530812_530965_+	hypothetical protein	NA	NA	NA	NA
WP_002986828.1\|530957_531224_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_111690656.1\|531543_532959_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
WP_111690657.1\|533037_533502_+	DUF4355 domain-containing protein	A0A141E167	Streptococcus_phage	5.7e-41	58.4
WP_111690658.1\|533505_534399_+\|capsid	phage major capsid protein	A0A126GGI3	Streptococcus_phage	1.7e-129	77.7
WP_111690659.1\|534549_534972_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	9.7e-48	68.6
WP_111690660.1\|534931_535270_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	1.3e-42	68.8
WP_002991575.1\|535262_535499_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	6.7e-22	67.9
WP_000573598.1\|535499_535835_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_172450336.1\|535850_536432_+\|tail	phage tail protein	M1NS84	Streptococcus_phage	9.9e-59	62.9
WP_111690662.1\|536441_536705_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_011528785.1\|536719_537091_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
WP_010922453.1\|537090_539448_+	hypothetical protein	M1NRG5	Streptococcus_phage	6.5e-141	50.6
WP_010922452.1\|539444_540140_+	hypothetical protein	A0A1B1P761	Bacillus_phage	7.6e-05	29.6
WP_111690663.1\|540136_542080_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	6.2e-97	50.0
WP_063629043.1\|542076_543192_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.7e-123	71.7
WP_111685861.1\|543206_544988_+	hypothetical protein	Q938J9	Temperate_phage	2.0e-73	42.8
WP_111690664.1\|544996_545425_+	DUF1617 family protein	Q938J8	Temperate_phage	2.8e-66	92.1
WP_111690665.1\|545427_546060_+	hypothetical protein	Q938J7	Temperate_phage	3.7e-43	49.5
WP_002988455.1\|546069_546525_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	5.2e-63	81.5
WP_111690666.1\|546636_547845_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.6e-210	85.6
WP_002985529.1\|548143_549943_-	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	2.9e-109	36.8

DBSCAN-SWA_5

577397 : 631328

Streptococcus_phage(60.34%)

capsid,terminase,holin,portal,head,protease,tail,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032467320.1\|577397_578522_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_096466706.1\|578590_579688_+	peptide chain release factor 2	NA	NA	NA	NA
WP_002985455.1\|579707_580400_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.0e-30	35.6
WP_002990498.1\|580392_581322_+	ABC transporter permease	NA	NA	NA	NA
WP_011284638.1\|581630_582329_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.0e-78	62.9
WP_032467289.1\|582496_583261_+	(S)-acetoin forming diacetyl reductase	NA	NA	NA	NA
WP_079993315.1\|583368_585870_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	6.3e-203	47.9
WP_002985439.1\|586204_587398_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_002985437.1\|587418_588765_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8
WP_002985434.1\|589179_590070_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_002985431.1\|590066_591044_+	YvcK family protein	A1IMD5	Streptococcus_phage	2.1e-138	74.2
WP_002985428.1\|591040_591952_+	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.3e-105	64.7
WP_011017563.1\|592128_593544_-	recombinase family protein	A5GZ62	Lactococcus_phage	1.4e-109	47.2
WP_002985420.1\|593666_593972_-	membrane protein	NA	NA	NA	NA
WP_002985417.1\|593981_594746_-	helix-turn-helix transcriptional regulator	E8ZDN4	Streptococcus_phage	2.0e-83	64.5
WP_002985414.1\|595105_595264_+	hypothetical protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
WP_001008979.1\|595362_596004_-	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_002985407.1\|596055_596244_+	helix-turn-helix transcriptional regulator	A0A0B5A7F0	Streptococcus_phage	2.6e-13	63.3
WP_002985404.1\|596292_597054_+	phage repressor protein/antirepressor Ant	A0A0C5AEJ9	Bacteriophage	1.6e-85	61.9
WP_011889039.1\|597194_597377_-	hypothetical protein	NA	NA	NA	NA
WP_002985395.1\|597463_597601_+	hypothetical protein	NA	NA	NA	NA
WP_002985392.1\|597602_597788_+	hypothetical protein	Q938N3	Temperate_phage	2.0e-21	83.6
WP_002985388.1\|598270_598657_+	DnaD domain-containing protein	Q938N2	Temperate_phage	2.8e-25	55.0
WP_002985387.1\|598637_598871_+	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_011017992.1\|598867_599008_+	hypothetical protein	NA	NA	NA	NA
WP_011017565.1\|599016_599223_+	hypothetical protein	NA	NA	NA	NA
WP_002988359.1\|599278_599608_+	hypothetical protein	J7KGX3	Streptococcus_phage	2.1e-45	83.5
WP_111690667.1\|599610_600537_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.9e-91	69.0
WP_000594115.1\|600533_600734_+	hypothetical protein	NA	NA	NA	NA
WP_002988362.1\|600726_601524_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	6.6e-130	83.8
WP_002985383.1\|601700_602042_+	hypothetical protein	M1NS23	Streptococcus_phage	3.1e-12	38.7
WP_002985380.1\|602038_602551_+	hypothetical protein	Q708P9	Streptococcus_phage	8.4e-62	73.2
WP_011017567.1\|602537_602735_+	hypothetical protein	A3F626	Streptococcus_phage	9.9e-11	86.5
WP_011017568.1\|602728_603013_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_002987593.1\|603009_603279_+	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011017569.1\|603288_603702_+	hypothetical protein	Q938M1	Temperate_phage	6.4e-36	65.2
WP_011017570.1\|603698_603983_+	hypothetical protein	A3F628	Streptococcus_phage	4.6e-33	79.8
WP_111690668.1\|603986_604472_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	2.0e-92	98.1
WP_030126040.1\|604473_605112_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	1.3e-80	65.2
WP_021340586.1\|605476_605914_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
WP_172450337.1\|606488_606746_-	hypothetical protein	NA	NA	NA	NA
WP_011017575.1\|606816_607746_+	DNA adenine methylase	A0A126HAU2	Lactococcus_phage	4.9e-100	71.8
WP_002987543.1\|607872_608250_-	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_001132273.1\|608301_608487_-	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002985375.1\|608722_609061_+	HNH endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
WP_002985371.1\|609231_609699_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_002985368.1\|609701_609932_+	hypothetical protein	NA	NA	NA	NA
WP_024623442.1\|609935_611690_+	amino acid transporter	J7KKD1	Streptococcus_phage	0.0e+00	96.1
WP_002985365.1\|611686_611857_+	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_002985363.1\|611849_612074_+	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_011017578.1\|612107_613328_+\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_011017579.1\|613305_613971_+\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	3.5e-92	78.1
WP_011017580.1\|613995_615183_+\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
WP_011017581.1\|615327_615630_+\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
WP_011017582.1\|615626_615974_+\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
WP_011527557.1\|615970_616348_+	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
WP_011017584.1\|616344_616770_+	hypothetical protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
WP_011017585.1\|616785_617394_+	hypothetical protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
WP_011017586.1\|617446_617773_+	hypothetical protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
WP_021299462.1\|617820_617970_+	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_002985338.1\|617982_621906_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.9e-238	48.5
WP_011527559.1\|621905_622613_+\|tail	phage tail family protein	Q938K2	Temperate_phage	6.8e-94	71.9
WP_011527560.1\|622609_624754_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	94.7
WP_011017589.1\|624750_625761_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	7.8e-136	75.8
WP_011527561.1\|625773_627660_+	gp58-like family protein	Q938J9	Temperate_phage	3.1e-218	84.7
WP_002983467.1\|627671_628103_+	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011017592.1\|628105_628723_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	5.0e-77	89.3
WP_002987582.1\|628732_629008_+	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_000609113.1\|629004_629232_+\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_002985329.1\|629347_630553_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.6e-204	83.3
WP_002985327.1\|630620_631328_-	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1

DBSCAN-SWA_6

715332 : 725935

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111690670.1\|715332_717543_-	LTA synthase family protein	W6LM83	Streptococcus_phage	7.7e-269	69.2
WP_002985142.1\|717650_718814_+	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_002985140.1\|718810_719497_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985136.1\|719590_720757_+	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002985134.1\|720817_721159_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
WP_002985132.1\|721379_722732_+	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	4.5e-30	24.0
WP_032467286.1\|724117_724558_-	membrane protein	NA	NA	NA	NA
WP_002985123.1\|724792_725935_+	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	4.1e-24	27.0

DBSCAN-SWA_7

1026977 : 1170283

151

Streptococcus_phage(36.23%)

capsid,terminase,integrase,holin,portal,transposase,head,tail,tRNA

attL 1116696:1116711|attR 1151355:1151370

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002984492.1\|1026977_1027862_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_002984490.1\|1027977_1029318_-	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_002984488.1\|1029414_1030371_-	aromatic acid exporter family protein	NA	NA	NA	NA
WP_002984487.1\|1030381_1030978_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_002984485.1\|1031069_1033706_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_002989664.1\|1033720_1034422_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
WP_002984482.1\|1034539_1035082_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002984480.1\|1035224_1035866_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002994467.1\|1036028_1036517_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984476.1\|1036527_1036728_-	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
WP_002984475.1\|1036768_1037308_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984473.1\|1037320_1037509_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984470.1\|1037519_1038131_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984469.1\|1038167_1038416_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002984467.1\|1038777_1041096_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.6e-131	41.2
WP_002984465.1\|1041624_1042947_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_002984464.1\|1043066_1044302_+	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_002984462.1\|1044671_1045445_-	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_002984460.1\|1045813_1046650_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002984457.1\|1046665_1047295_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-27	35.5
WP_002984455.1\|1047304_1047946_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002984453.1\|1048052_1048388_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002984451.1\|1048583_1050398_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.2e-98	38.9
WP_002984449.1\|1050573_1051131_-	signal peptidase I	NA	NA	NA	NA
WP_002984447.1\|1051348_1052851_-	pyruvate kinase	NA	NA	NA	NA
WP_002984444.1\|1052913_1053927_-	6-phosphofructokinase	NA	NA	NA	NA
WP_002984441.1\|1054006_1057117_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	1.4e-119	29.8
WP_032467272.1\|1057301_1057673_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_002984437.1\|1057672_1058371_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.6e-09	27.3
WP_002984433.1\|1058380_1059166_+	hypothetical protein	NA	NA	NA	NA
WP_002989607.1\|1059296_1059911_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
WP_002984426.1\|1060501_1060690_-	hypothetical protein	A3F673	Streptococcus_phage	1.3e-20	83.1
WP_011285611.1\|1060927_1061728_+	streptodornase Sda3	NA	NA	NA	NA
WP_002984418.1\|1062503_1063709_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.7e-207	84.5
WP_003058873.1\|1063824_1064052_-\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_002987582.1\|1064048_1064324_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_047235258.1\|1064333_1064951_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.4e-79	89.3
WP_002987333.1\|1064953_1065115_-	hypothetical protein	NA	NA	NA	NA
WP_002987337.1\|1065128_1067039_-	gp58-like family protein	Q938J9	Temperate_phage	6.0e-121	71.3
WP_047235257.1\|1067051_1068059_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.4e-137	71.7
WP_002984413.1\|1068055_1070107_-\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	84.3
WP_002984411.1\|1070103_1070883_-\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.9e-68	55.5
WP_047235256.1\|1070914_1074181_-	tape measure protein	U6E979	Streptococcus_phage	1.6e-04	30.4
WP_002984407.1\|1074195_1074525_-	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	2.0e-11	41.5
WP_002984405.1\|1074566_1074926_-	hypothetical protein	D7RWD6	Brochothrix_phage	4.3e-20	44.5
WP_002984403.1\|1074978_1075581_-\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	1.3e-40	52.0
WP_002984401.1\|1075636_1076026_-	hypothetical protein	Q38611	Lactococcus_phage	3.5e-44	68.2
WP_002984399.1\|1076022_1076388_-	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	7.7e-17	46.3
WP_002984393.1\|1076368_1076677_-	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	5.7e-13	40.2
WP_002984392.1\|1076673_1077027_-\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
WP_002984390.1\|1077040_1077283_-	hypothetical protein	NA	NA	NA	NA
WP_002984388.1\|1077292_1078369_-\|capsid	major capsid protein	A0A2H4J022	uncultured_Caudovirales_phage	5.5e-103	56.0
WP_002984386.1\|1078368_1078749_-	phage protein	A0A0K2CNR0	Brevibacillus_phage	5.2e-08	37.9
WP_002984384.1\|1078758_1079292_-	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.4e-14	83.9
WP_002984382.1\|1079403_1080147_-	phage repressor protein/antirepressor Ant	M1PKL6	Streptococcus_phage	5.3e-73	56.9
WP_002984380.1\|1080148_1080397_-	hypothetical protein	NA	NA	NA	NA
WP_011017861.1\|1080511_1080691_-	hypothetical protein	M1NRK8	Streptococcus_phage	2.6e-18	79.7
WP_002984375.1\|1080786_1081056_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.3e-34	84.1
WP_010922213.1\|1081115_1081295_-	hypothetical protein	NA	NA	NA	NA
WP_002984371.1\|1081285_1082911_-\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	1.1e-46	43.8
WP_002984369.1\|1082891_1084394_-\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
WP_047235253.1\|1084405_1085713_-\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	8.5e-183	75.0
WP_047235590.1\|1085690_1086158_-\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.9e-52	70.8
WP_001132273.1\|1086220_1086406_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1086457_1086835_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_002990048.1\|1087151_1087364_+	hypothetical protein	NA	NA	NA	NA
WP_011284864.1\|1087453_1088368_-	hypothetical protein	NA	NA	NA	NA
WP_003052405.1\|1089289_1089727_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	3.6e-77	100.0
WP_002987471.1\|1089995_1090631_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.5e-87	67.9
WP_002987468.1\|1090630_1091032_-	hypothetical protein	NA	NA	NA	NA
WP_011017571.1\|1091222_1091705_-	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_011889038.1\|1091708_1091993_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.0e-37	88.3
WP_047235252.1\|1092193_1092463_-	hypothetical protein	Q938M2	Temperate_phage	2.5e-41	87.6
WP_020905119.1\|1092459_1092744_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	2.0e-49	98.9
WP_002984340.1\|1092970_1093327_-	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	5.1e-58	95.8
WP_002984338.1\|1093310_1093661_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.6e-46	89.4
WP_002984334.1\|1093614_1094484_-	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	3.7e-102	64.9
WP_002984332.1\|1094750_1096304_-	hypothetical protein	A0A1P8BM51	Lactococcus_phage	4.3e-210	70.4
WP_002984328.1\|1096321_1096804_-	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
WP_075340263.1\|1096808_1098212_-	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
WP_002984321.1\|1098247_1098931_-	AAA family ATPase	J7KC09	Streptococcus_phage	9.4e-125	99.1
WP_002984318.1\|1098927_1099212_-	hypothetical protein	NA	NA	NA	NA
WP_002984315.1\|1099208_1099403_-	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_002984312.1\|1099402_1099732_-	hypothetical protein	A1EAC2	Streptococcus_phage	2.7e-13	41.6
WP_002984309.1\|1099812_1099950_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	4.9e-17	97.8
WP_002984306.1\|1099946_1100243_-	MerR family transcriptional regulator	A0A097PAT8	Streptococcus_pyogenes_phage	4.6e-44	86.7
WP_002984304.1\|1100320_1100506_-	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	1.2e-18	70.5
WP_002984301.1\|1100631_1100868_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1101040_1101250_+	hypothetical protein	NA	NA	NA	NA
WP_011017884.1\|1101508_1102018_+	hypothetical protein	NA	NA	NA	NA
WP_002984281.1\|1102125_1102353_-	hypothetical protein	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
WP_023605145.1\|1102426_1102909_+	hypothetical protein	NA	NA	NA	NA
WP_021340823.1\|1102905_1103052_-	hypothetical protein	NA	NA	NA	NA
WP_002984272.1\|1103212_1103950_+	helix-turn-helix domain-containing protein	A0A1S5S8T5	Streptococcus_phage	2.7e-77	63.9
WP_002984270.1\|1103962_1104772_+	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	3.8e-24	35.8
WP_002984265.1\|1105021_1106110_+\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	4.2e-204	99.4
WP_002989605.1\|1106472_1107093_+	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_002984256.1\|1107349_1109614_-	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
WP_002984251.1\|1109648_1111142_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_002992583.1\|1111256_1112276_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.7e-17	27.8
WP_002984246.1\|1112519_1113767_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_002984244.1\|1114040_1115402_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002984240.1\|1115401_1116238_+	sugar ABC transporter permease	NA	NA	NA	NA
1116696:1116711	attL	NA	NA	NA	NA
WP_002984221.1\|1117712_1118696_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_002984219.1\|1118726_1119977_-	D-alanyl-lipoteichoic acid biosynthesis protein DltD	NA	NA	NA	NA
WP_002984216.1\|1119969_1120209_-	D-alanine--poly(phosphoribitol) ligase subunit DltC	NA	NA	NA	NA
WP_002984207.1\|1120226_1121483_-	D-alanyl-lipoteichoic acid biosynthesis protein DltB	NA	NA	NA	NA
WP_002984203.1\|1121479_1123018_-	D-alanine--poly(phosphoribitol) ligase subunit DltA	A0A2K9KZV5	Tupanvirus	5.0e-41	28.2
WP_002984200.1\|1123029_1123173_-	teichoic acid D-Ala incorporation-associated protein DltX	NA	NA	NA	NA
WP_002984194.1\|1123436_1125428_-	excinuclease ABC subunit B	NA	NA	NA	NA
WP_002984191.1\|1125620_1127795_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_002984187.1\|1127794_1128535_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-35	42.1
WP_002984179.1\|1128830_1130210_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002984176.1\|1130400_1130835_-	DUF3284 domain-containing protein	NA	NA	NA	NA
WP_002984173.1\|1130831_1131167_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002984171.1\|1131169_1131481_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002984167.1\|1131503_1133498_-	BglG family transcription antiterminator	NA	NA	NA	NA
WP_002984164.1\|1133603_1134698_-	DUF871 domain-containing protein	NA	NA	NA	NA
WP_032467269.1\|1134706_1136107_-	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_002984157.1\|1136331_1137027_+	nicotinamide riboside transporter PnuC	NA	NA	NA	NA
WP_002984154.1\|1137031_1137190_-	hypothetical protein	NA	NA	NA	NA
WP_002984148.1\|1137258_1138572_-	GTPase ObgE	NA	NA	NA	NA
WP_002984145.1\|1138628_1138757_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_168389357.1\|1138998_1140340_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.8e-63	49.4
WP_002992869.1\|1140640_1141513_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_002984130.1\|1141736_1143047_+	C4-dicarboxylate ABC transporter	NA	NA	NA	NA
WP_002987505.1\|1143124_1143418_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_002987502.1\|1143450_1143804_+\|transposase	transposase	A0A0C5AEB1	Paenibacillus_phage	1.6e-06	30.8
WP_172450329.1\|1143849_1144173_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1P8CWQ3	Bacillus_phage	3.3e-19	46.2
WP_014407646.1\|1144189_1144921_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_002984124.1\|1145035_1145401_+	thioesterase family protein	NA	NA	NA	NA
WP_002984119.1\|1145520_1146741_-	MFS transporter	NA	NA	NA	NA
WP_011888813.1\|1147114_1148599_+	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_002984115.1\|1148703_1149105_-	PaaI family thioesterase	NA	NA	NA	NA
WP_002984111.1\|1149895_1151284_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	D0R096	Streptococcus_phage	5.0e-258	98.0
WP_002984109.1\|1151332_1152784_-	LCP family protein	NA	NA	NA	NA
1151355:1151370	attR	NA	NA	NA	NA
WP_002984106.1\|1152991_1153483_-	shikimate kinase	NA	NA	NA	NA
WP_002984103.1\|1153475_1154759_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002984102.1\|1154869_1155835_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_002984100.1\|1155836_1156697_-	methionyl aminopeptidase	NA	NA	NA	NA
WP_002984098.1\|1156712_1157996_-	CBS domain-containing protein	NA	NA	NA	NA
WP_002984095.1\|1158004_1158547_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002984090.1\|1158784_1159522_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002984086.1\|1159878_1161138_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002984082.1\|1161311_1162508_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-137	65.2
WP_002984080.1\|1163044_1165423_-	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_002984078.1\|1165626_1166568_+	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_172450324.1\|1166542_1166746_-	DUF3272 domain-containing protein	NA	NA	NA	NA
WP_002984073.1\|1166840_1168511_-	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	5.1e-47	40.6
WP_009881127.1\|1168510_1169008_-	GAF domain-containing protein	NA	NA	NA	NA
WP_002987482.1\|1169149_1170283_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1390929 : 1471788

Streptococcus_phage(74.07%)

bacteriocin,capsid,terminase,integrase,holin,portal,head,tail,tRNA

attL 1431679:1431695|attR 1471834:1471850

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002983572.1\|1390929_1391196_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_032467313.1\|1391388_1393374_-	transketolase	NA	NA	NA	NA
WP_002983569.1\|1393591_1394236_-	fructose-6-phosphate aldolase	A0A0C5AMY8	Cyanophage	2.2e-43	44.2
WP_002983565.1\|1394361_1395861_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002983562.1\|1395850_1397197_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002983560.1\|1397305_1398007_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	1.2e-29	37.2
WP_002983558.1\|1398008_1399847_-	type 1 glycerol-3-phosphate oxidase	NA	NA	NA	NA
WP_002983556.1\|1399862_1401389_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_011054910.1\|1401748_1402141_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_002983550.1\|1402268_1402526_-	DUF896 family protein	NA	NA	NA	NA
WP_002983546.1\|1402679_1404719_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_002983544.1\|1405095_1406013_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_002983542.1\|1406383_1406917_-	isoprenylcysteine carboxyl methyltransferase family protein	NA	NA	NA	NA
WP_002983539.1\|1407048_1407888_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	2.5e-50	40.3
WP_002983538.1\|1408009_1409158_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_002983536.1\|1409275_1410907_-	Na/Pi cotransporter family protein	A0A1B1ITU5	uncultured_Mediterranean_phage	2.7e-05	38.8
WP_002983530.1\|1411108_1411831_+	hypothetical protein	NA	NA	NA	NA
WP_002983528.1\|1411959_1412802_-	DegV family protein	A0A1X9I5J4	Streptococcus_phage	1.3e-91	61.9
WP_002983526.1\|1413094_1413652_+	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.2e-14	60.3
WP_002983525.1\|1413687_1414512_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002983523.1\|1414513_1415131_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_002983521.1\|1415327_1416305_-	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_002983519.1\|1416386_1416650_-	tagatose-6-phosphate kinase	NA	NA	NA	NA
WP_002983517.1\|1416814_1417330_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002983515.1\|1417344_1417770_-	galactose-6-phosphate isomerase subunit LacA	A0A222YX14	Synechococcus_phage	4.9e-07	28.6
WP_002983513.1\|1418026_1419478_-	PTS galactitol transporter subunit IIC	NA	NA	NA	NA
WP_002983511.1\|1419503_1419809_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002983508.1\|1419801_1420275_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002983505.1\|1420511_1421282_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	6.4e-21	27.8
WP_002983501.1\|1421485_1421689_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_002983499.1\|1421702_1423934_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.9e-114	37.5
WP_011018099.1\|1423933_1424368_-	CopY/TcrY family copper transport repressor	NA	NA	NA	NA
WP_002983494.1\|1424539_1425529_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002988820.1\|1425659_1426010_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002983491.1\|1426215_1429077_-	translation initiation factor IF-2	E3T4N3	Cafeteria_roenbergensis_virus	4.5e-19	25.2
WP_002983488.1\|1429096_1429399_-	YlxQ-related RNA-binding protein	NA	NA	NA	NA
WP_002983486.1\|1429391_1429688_-	YlxR family protein	NA	NA	NA	NA
WP_002983485.1\|1429703_1430861_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_002983483.1\|1431035_1431572_-	ribosome maturation factor RimP	NA	NA	NA	NA
1431679:1431695	attL	NA	NA	NA	NA
WP_002983481.1\|1431816_1431996_-	hypothetical protein	A3F673	Streptococcus_phage	5.2e-19	79.7
WP_002983479.1\|1432062_1432857_-	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	8.9e-26	35.6
WP_002983477.1\|1433101_1434316_-	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	9.7e-165	60.5
WP_002983475.1\|1434427_1434883_-\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	3.0e-63	81.5
WP_002983470.1\|1434893_1435526_-	hypothetical protein	Q938J7	Temperate_phage	4.3e-47	51.9
WP_002983467.1\|1435528_1435960_-	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_111690677.1\|1435971_1437990_-	gp58-like family protein	Q938J9	Temperate_phage	2.7e-172	69.5
WP_111680780.1\|1438002_1439124_-	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.6e-126	71.2
WP_002983450.1\|1439123_1441163_-\|tail	phage tail protein	A7J2A7	Streptococcus_phage	0.0e+00	91.0
WP_002983449.1\|1441172_1442015_-\|tail	phage tail family protein	A7J2A6	Streptococcus_phage	5.5e-159	98.6
WP_002983445.1\|1446066_1446300_-	hypothetical protein	A7J2A4	Streptococcus_phage	4.4e-34	100.0
WP_002983443.1\|1446374_1446830_-	hypothetical protein	A7J2A3	Streptococcus_phage	8.3e-77	100.0
WP_002983441.1\|1446883_1447483_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	2.2e-93	100.0
WP_002983439.1\|1447494_1447854_-	hypothetical protein	A7J2A1	Streptococcus_phage	2.1e-59	100.0
WP_000639437.1\|1448196_1448475_-	hypothetical protein	A7J299	Streptococcus_phage	4.2e-47	98.9
WP_002983431.1\|1448485_1448842_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	2.5e-57	98.3
WP_002983429.1\|1448853_1449741_-	hypothetical protein	A7J297	Streptococcus_phage	2.1e-161	100.0
WP_002983425.1\|1449753_1450323_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.0e-79	97.4
WP_002983424.1\|1450483_1450750_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.1e-33	85.2
WP_002983423.1\|1450752_1450941_-	hypothetical protein	A7J294	Streptococcus_phage	1.4e-22	98.4
WP_002983422.1\|1450971_1452417_-\|capsid	minor capsid protein	A7J293	Streptococcus_phage	4.5e-270	96.7
WP_002983421.1\|1452376_1453909_-\|portal	phage portal protein	A7J292	Streptococcus_phage	4.3e-287	98.2
WP_002983420.1\|1453923_1455201_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	3.5e-242	98.1
WP_032467259.1\|1455190_1455643_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.0e-71	93.3
WP_002983418.1\|1455738_1456152_-	transcriptional regulator	A7J289	Streptococcus_phage	5.8e-45	64.2
WP_032467258.1\|1456284_1456551_-	hypothetical protein	A7J287	Streptococcus_phage	7.3e-17	60.0
WP_002983415.1\|1456553_1456715_-	hypothetical protein	A7J285	Streptococcus_phage	1.2e-22	94.3
WP_002983414.1\|1456715_1458038_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	4.6e-253	98.0
WP_002983413.1\|1458034_1458310_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	8.6e-45	96.7
WP_002983412.1\|1458676_1461061_-	DNA primase	A7J282	Streptococcus_phage	8.8e-287	97.6
WP_002983411.1\|1461065_1462997_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	87.8
WP_002983410.1\|1463039_1463603_-	DUF2815 family protein	D2J040	Enterococcus_phage	7.4e-51	57.9
WP_002983409.1\|1463616_1464774_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.7e-219	99.7
WP_002983408.1\|1464773_1465073_-	hypothetical protein	A7J277	Streptococcus_phage	1.0e-38	92.9
WP_002983407.1\|1465160_1465364_-	hypothetical protein	A7J276	Streptococcus_phage	9.4e-33	100.0
WP_002983406.1\|1465360_1465513_-	hypothetical protein	A7J275	Streptococcus_phage	4.4e-19	100.0
WP_002983405.1\|1465509_1465893_-	hypothetical protein	A7J274	Streptococcus_phage	7.2e-66	100.0
WP_002983404.1\|1465889_1466096_-	hypothetical protein	NA	NA	NA	NA
WP_002983403.1\|1466088_1466259_-	hypothetical protein	A7J273	Streptococcus_phage	2.0e-20	89.3
WP_032467257.1\|1466255_1466531_-	DNA-binding phage protein	A7J272	Streptococcus_phage	1.7e-45	95.6
WP_002983400.1\|1466589_1466799_-	helix-turn-helix transcriptional regulator	M1Q1B4	Streptococcus_phage	7.7e-14	53.6
WP_002983399.1\|1467090_1467438_+	helix-turn-helix transcriptional regulator	A0A126GGQ7	Streptococcus_phage	1.5e-41	73.5
WP_002983397.1\|1467441_1467828_+	ImmA/IrrE family metallo-endopeptidase	Q7Y4M1	Streptococcus_phage	1.3e-38	58.4
WP_002983395.1\|1467952_1469674_+	AAA family ATPase	NA	NA	NA	NA
WP_111680774.1\|1469730_1470588_+	DNA adenine methylase	A0A2H4UUI2	Bodo_saltans_virus	9.9e-15	29.3
WP_002983389.1\|1470708_1471788_+\|integrase	site-specific integrase	A7J266	Streptococcus_phage	7.5e-177	93.3
1471834:1471850	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483351

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection