CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483347	Streptococcus pyogenes strain NCTC8324 chromosome 1	2 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csm6,DinG,csa3	0	8	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483347_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483347_1

658084-658377

TypeI

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRT

4 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_LS483347_1

>merge|NZ_LS483347|1|658084-658377|PILER-CR,CRISPRCasFinder,CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAATATCAATATCTCCTTTAATAATGATTAATGTCAAAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTCCTTAATTAAATGTATTACTCGTACGAGAATAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTTTTCGGATATAACTGATTTTTGGTTAAAGGATGTCTCACCCTTCATGGGTGAGTGGATTGAAATTCCTCTCATCATATCTTTTAAATCTTTAACATCGTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_LS483347|1|1|658084-658377|PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATCAATATCTCCTTTAATAATGATTAATGTCAAA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TCCTTAATTAAATGTATTACTCGTACGAGAATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTTTTCGGATATAACTGATTTTTGGTTAAAGGAT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TCCTCTCATCATATCTTTTAAATCTTTAACATC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_LS483347|1|1|658084-658376|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TATCAATATCTCCTTTAATAATGATTAATGTCAAA
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TTCCTTAATTAAATGTATTACTCGTACGAGAATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TTTTTTCGGATATAACTGATTTTTGGTTAAAGGAT
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TTCCTCTCATCATATCTTTTAAATCTTTAACATC
GTCTCACCCTTCATGGGTGAGTGGATTGAAA

>NZ_LS483347|1|1|658084-658377|CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATCAATATCTCCTTTAATAATGATTAATGTCAAA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TCCTTAATTAAATGTATTACTCGTACGAGAATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTTTTCGGATATAACTGATTTTTGGTTAAAGGAT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TCCTCTCATCATATCTTTTAAATCTTTAACATC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483347.1\|WP_002983792.1\|665646_666120_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483347.1\|WP_003060901.1\|655934_656609_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_LS483347.1\|WP_111688438.1\|659925_661032_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483347.1\|WP_014612476.1\|655084_655933_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_LS483347.1\|WP_002983795.1\|666261_666942_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483347.1\|WP_085613947.1\|652456_653185_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483347.1\|WP_085613964.1\|661119_661860_+\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483347.1\|WP_085613948.1\|653184_655080_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
NZ_LS483347.1\|WP_002983786.1\|663662_664742_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483347.1\|WP_014407704.1\|667215_668451_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_LS483347.1\|WP_085613965.1\|664764_665481_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LS483347.1\|WP_002983778.1\|659259_659883_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483347.1\|WP_002989044.1\|657641_657935_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LS483347.1\|WP_085613946.1\|649915_652324_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483347.1\|WP_085613944.1\|646548_647097_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483347.1\|WP_085613950.1\|656605_657631_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483347.1\|WP_172451640.1\|646139_646547_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_LS483347.1\|WP_053308508.1\|658536_659247_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483347.1\|WP_085613945.1\|647110_649762_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483347.1\|WP_032460497.1\|661856_663590_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519

Protein	Function_ID	Function_description	E-value
NZ_LS483347.1\|WP_002983792.1\|665646_666120_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.23847e-66
NZ_LS483347.1\|WP_003060901.1\|655934_656609_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	1.18604e-43
NZ_LS483347.1\|WP_111688438.1\|659925_661032_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	1.29148e-162
NZ_LS483347.1\|WP_014612476.1\|655084_655933_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	1.72617e-159
NZ_LS483347.1\|WP_002983795.1\|666261_666942_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
NZ_LS483347.1\|WP_085613947.1\|652456_653185_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	7.90931e-117
NZ_LS483347.1\|WP_085613964.1\|661119_661860_+\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.85886e-83
NZ_LS483347.1\|WP_085613948.1\|653184_655080_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	0
NZ_LS483347.1\|WP_002983786.1\|663662_664742_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	6.03775e-33
NZ_LS483347.1\|WP_014407704.1\|667215_668451_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_LS483347.1\|WP_085613965.1\|664764_665481_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	5.96228e-102
NZ_LS483347.1\|WP_002983778.1\|659259_659883_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.89498e-35
NZ_LS483347.1\|WP_002989044.1\|657641_657935_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
NZ_LS483347.1\|WP_085613946.1\|649915_652324_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.21306e-160
NZ_LS483347.1\|WP_085613950.1\|656605_657631_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483347.1\|WP_172451640.1\|646139_646547_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.67701e-09
NZ_LS483347.1\|WP_053308508.1\|658536_659247_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.251e-41
NZ_LS483347.1\|WP_085613945.1\|647110_649762_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483347.1\|WP_032460497.1\|661856_663590_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	7.94305e-62

>NZ_LS483347.1|WP_002989044.1|657641_657935_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LS483347.1|WP_085613950.1|656605_657631_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVTDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQFQKKHFEVKENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LS483347.1|WP_003060901.1|655934_656609_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>NZ_LS483347.1|WP_014612476.1|655084_655933_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LS483347.1|WP_085613948.1|653184_655080_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFSYYSAEMGQTQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQHNQLKVTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNQREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>NZ_LS483347.1|WP_085613947.1|652456_653185_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGINIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_LS483347.1|WP_085613946.1|649915_652324_+|CRISPR-associated-helicase/endonuclease-Cas3
MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKKLCDYGYKDLRELIDKAFDNYQQSMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTGDLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEIDHRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVLAIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLNIYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLSAEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSASFYF
>NZ_LS483347.1|WP_085613945.1|647110_649762_+|valine--tRNA-ligase
MPKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGISRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_LS483347.1|WP_085613944.1|646548_647097_+|hypothetical-protein
MSKMKTMLKSEKRNSASRYYITKADKMFNVINSGLNRISKEAKRNLAYSLRYLEFLQLQLDELVLDDMMIKMIHKNFIITSLAIIELIMQDSTNANVYGEKLLIEFRNKNLFNLKDEDFEKLDKFRKLRNRVHLQLRFEDDQTDWFAFEKCDYLDMKKLLYQILTSEKMFNKPYRTYIDFLK
>NZ_LS483347.1|WP_172451640.1|646139_646547_+|GNAT-family-N-acetyltransferase
MVKMLLEVYNRKTLPKVETERLLLRQRKLEDAEAIFAFAKLAEVSYPAGFPPVKSLADESAYLQDIYPANLEKEGLPSGYGITLKDNDNVIGSVDFNPDELAKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483347.1|WP_053308508.1|658536_659247_+|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSIVLIASVFAAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483347.1|WP_002983778.1|659259_659883_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483347.1|WP_111688438.1|659925_661032_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNVPVDQKVIYLAGGCFWGVEEYFSQVNGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483347.1|WP_085613964.1|661119_661860_+|response-regulator
MYSLLIVEDEYLVRQGIRSLIDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVSVTPSQYKKGGQA
>NZ_LS483347.1|WP_032460497.1|661856_663590_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNPQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSSKKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQHQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLTYDVQGLDAYADFIIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSETAQHLILTVWDNGKGIEASALTNSQSLLTRGGVGLKNVDQRLKLQYGEAYQMTIQSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_LS483347.1|WP_002983786.1|663662_664742_+|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLVAYGFEKRDNGYFYNERFMEGEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKVTHDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYACQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKKHGVAAVRGPRRLSPQLIAFLKEKEYLKENN
>NZ_LS483347.1|WP_085613965.1|664764_665481_+|B3/4-domain-containing-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNSQSIPSINPLVDIYNAASLRFGLPVGAEDSDSFIRDLRLTTTDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALEFIEGSAKMYLHATPSLHVLDKDNPHVPLFTEN
>NZ_LS483347.1|WP_002983792.1|665646_666120_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483347.1|WP_002983795.1|666261_666942_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_LS483347.1|WP_014407704.1|667215_668451_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESSYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Crispr_ID: NZ_LS483347_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483347_2

1733655-1733902

Orphan

Consensus_repeat	Method
GGAGTTTCTGGGGCCGCTGGAGTTGATGGAGATGGGGTTTCCTCAGAAGATGC	PILER-CR

2 spacers

The CRISPR arrays of NZ_LS483347_2

>merge|NZ_LS483347|2|1733655-1733902|PILER-CR
GCTGGAGTTGATGGAGACGGGCTTGTCGTAGCTGCTACTGAAGATTCTTCACTCTCAGCTGGTTGAGCTGGAGCCTCAGATAAAGCTGGGGTTTCTGGGGCCGCTGGAGTTGATGGAGATGGGGTTTCCTCAGAAGATGCTGCTACTGAAGGTTCCTCACTCTCAGGTGATGGAGCTGGAGCTGCTGGTTCTTCAGGAGTTTCTGGGGCCGCTGGAGTTGATGGAGATGGGGTTTCCTCAGAAGATGC

>NZ_LS483347|2|2|1733655-1733902|PILER-CR
GCTGGAGTTGATGGAGACGGGCTTGTCGTAGCTGCTACTGAAGATTCTTCACT	CTCAGCTGGTTGAGCTGGAGCCTCAGATAAAGCTGGGGTTTCTGGGGCCGCTGGAGTTGATGGAGA
TGGGGTTTCCTCAGAAGATGCTGCTACTGAAGGTTCCTCACTCTCAGGTGATG	GAGCTGGAGCTGCTGGTTCTTCAGGAGTTTCTGGGGCCGCTGGAGTTGATGGAGA
TGGGGTTTCCTCAGAAGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483347.1\|WP_002982466.1\|1746888_1748277_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_LS483347.1\|WP_020905530.1\|1727823_1728627_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NZ_LS483347.1\|WP_023079287.1\|1722090_1722597_+\|DNA-topology-modulation-protein	unknown	unknown	gnl\|CDD\|180911
NZ_LS483347.1\|WP_003056043.1\|1744829_1745081_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483347.1\|WP_085613617.1\|1745158_1746787_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NZ_LS483347.1\|WP_085613624.1\|1726016_1726994_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NZ_LS483347.1\|WP_023079146.1\|1732170_1733091_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NZ_LS483347.1\|WP_085613615.1\|1750250_1750925_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_LS483347.1\|WP_085613622.1\|1729686_1732158_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NZ_LS483347.1\|WP_085613616.1\|1749020_1750238_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NZ_LS483347.1\|WP_085613660.1\|1741211_1742366_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|274008
NZ_LS483347.1\|WP_023078564.1\|1726990_1727812_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NZ_LS483347.1\|WP_002991237.1\|1748273_1748927_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_LS483347.1\|WP_002982507.1\|1729318_1729519_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NZ_LS483347.1\|WP_023078565.1\|1728610_1729237_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NZ_LS483347.1\|WP_111688559.1\|1739759_1740986_-\|YSIRK-type-signal-peptide-containing-protein	unknown	unknown	gnl\|CDD\|224117
NZ_LS483347.1\|WP_111688557.1\|1734589_1738138_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NZ_LS483347.1\|WP_085613625.1\|1722841_1723546_+\|exotoxin	unknown	unknown	gnl\|CDD\|280949
NZ_LS483347.1\|WP_021775366.1\|1724275_1725904_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NZ_LS483347.1\|WP_011285226.1\|1750911_1752180_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914

Protein	Function_ID	Function_description	E-value
NZ_LS483347.1\|WP_020905530.1\|1727823_1728627_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.35923e-80
NZ_LS483347.1\|WP_023079287.1\|1722090_1722597_+\|DNA-topology-modulation-protein	gnl\|CDD\|180911	PRK07261, PRK07261, DNA topology modulation protein.	3.38385e-113
NZ_LS483347.1\|WP_002982466.1\|1746888_1748277_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.2074e-30
NZ_LS483347.1\|WP_085613617.1\|1745158_1746787_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.49185e-58
NZ_LS483347.1\|WP_085613624.1\|1726016_1726994_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.99462e-108
NZ_LS483347.1\|WP_023079146.1\|1732170_1733091_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	4.61335e-123
NZ_LS483347.1\|WP_085613615.1\|1750250_1750925_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.99228e-116
NZ_LS483347.1\|WP_085613622.1\|1729686_1732158_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NZ_LS483347.1\|WP_085613616.1\|1749020_1750238_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	6.42325e-52
NZ_LS483347.1\|WP_085613660.1\|1741211_1742366_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	1.29165e-17
NZ_LS483347.1\|WP_023078564.1\|1726990_1727812_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.54341e-69
NZ_LS483347.1\|WP_002991237.1\|1748273_1748927_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NZ_LS483347.1\|WP_002982507.1\|1729318_1729519_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.43573e-06
NZ_LS483347.1\|WP_023078565.1\|1728610_1729237_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.7721e-91
NZ_LS483347.1\|WP_111688559.1\|1739759_1740986_-\|YSIRK-type-signal-peptide-containing-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	4.40189e-11
NZ_LS483347.1\|WP_111688557.1\|1734589_1738138_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	3.65112e-76
NZ_LS483347.1\|WP_085613625.1\|1722841_1723546_+\|exotoxin	gnl\|CDD\|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.25375e-40
NZ_LS483347.1\|WP_021775366.1\|1724275_1725904_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NZ_LS483347.1\|WP_011285226.1\|1750911_1752180_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	3.9346e-22

>NZ_LS483347.1|WP_023079146.1|1732170_1733091_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKNAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPNGNKTYLENLRANLEVLYQQLK
>NZ_LS483347.1|WP_085613622.1|1729686_1732158_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGRGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELSAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYIMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NZ_LS483347.1|WP_002982507.1|1729318_1729519_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NZ_LS483347.1|WP_023078565.1|1728610_1729237_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIVISHDFDMLKKLCDACYMIEENRTQLFKHT
>NZ_LS483347.1|WP_020905530.1|1727823_1728627_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIRQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NZ_LS483347.1|WP_023078564.1|1726990_1727812_+|ABC-transporter-permease
MILRRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NZ_LS483347.1|WP_085613624.1|1726016_1726994_+|ABC-transporter-permease
MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMSSVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGTSFILMGLSWILSGLIGFILGTLSAFHQGKLLDRIVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NZ_LS483347.1|WP_021775366.1|1724275_1725904_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NZ_LS483347.1|WP_085613625.1|1722841_1723546_+|exotoxin
MYEKNKTYFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEYSDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDRIAVFSVPFDWNYLSKGKVTAYTYGGITPYQKTSIPKNIPVNLWINRKQIPVPYNQISTNKTTVTAQEIDLKVRKFLISQHQLYSSGSNYKSGKLVFHTNDNSDKYSLDLFYTGYRDKESIFKVYKDNKSFNIDKIGHLDIEIDS
>NZ_LS483347.1|WP_023079287.1|1722090_1722597_+|DNA-topology-modulation-protein
MKIAIIGHSGSGKSTLARFLGQHYHCEVFHLDQLHFSSNWQERSDHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEADYIIYVNFSRFHCVYRAFKRYLNYRGKTRPDMADNCQEKFDVAFVKWILLGGRSRNQLKKYQSVIQKYPHKTIVLTNQKQLSHYMNTIN
>NZ_LS483347.1|WP_111688557.1|1734589_1738138_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVETPQPTAVSEEAPSSSKETKIPQTPGDAEETVADDANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTDDHQAKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNSKKTITFNATPKVLPTASDTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVVNGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGGTVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQAPDKKPETKPEQDGSDQAPDKKPETKPEQDGSDQAPDKKPEAKPEQDGSSQTPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLPTTNDKDSNRLHLLKLVMTTFFLGLVAHIFKTKRTED
>NZ_LS483347.1|WP_111688559.1|1739759_1740986_-|YSIRK-type-signal-peptide-containing-protein
MARKDMNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAESPKSHSISNNEQLINELNDLIEENNDLKDKLARNLDLLDNTREKDPQYRALMGENQDLREKEGKYQDKIKKLEEKEKNLEKKSEDVERHYLKKLDQEHKEQQERQKNLEELERQSQREIDKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASREAKKKVEADLAALTAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADLAALTAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPSTGETANPFFTAAAATVMVSAGMLALKRKEEN
>NZ_LS483347.1|WP_085613660.1|1741211_1742366_-|YSIRK-type-signal-peptide-containing-protein
MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAENEHLDVVLSAKEANKVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQQALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREMAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQSEVATLENLLGSAKRELTDLQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLALKRKEEN
>NZ_LS483347.1|WP_003056043.1|1744829_1745081_-|hypothetical-protein
MIKKVTTPSQKIKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NZ_LS483347.1|WP_085613617.1|1745158_1746787_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPNKDKNDTNQPDSSDQSTPSPKDQSSQKESQNKDGRSTPSPDQPKDQTPDKTPEKSPDKTPEKGPEKATEKTPEPNRDASKPIQPPLGAAAPVFAPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKGSNMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP
>NZ_LS483347.1|WP_002982466.1|1746888_1748277_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLIFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NZ_LS483347.1|WP_002991237.1|1748273_1748927_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NZ_LS483347.1|WP_085613616.1|1749020_1750238_-|ABC-transporter-permease
MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQMIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NZ_LS483347.1|WP_085613615.1|1750250_1750925_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEYSDIE
>NZ_LS483347.1|WP_011285226.1|1750911_1752180_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448845	Streptococcus phage Javan118, complete genome	21471-21504	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448973	Streptococcus phage Javan522, complete genome	39811-39843	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448942	Streptococcus phage Javan448, complete genome	24643-24675	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448965	Streptococcus phage Javan506, complete genome	40063-40095	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448970	Streptococcus phage Javan516, complete genome	44670-44702	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448959	Streptococcus phage Javan488, complete genome	39665-39697	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448778	Streptococcus phage Javan493, complete genome	39454-39486	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448963	Streptococcus phage Javan498, complete genome	30341-30373	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448949	Streptococcus phage Javan460, complete genome	40461-40493	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448975	Streptococcus phage Javan526, complete genome	40245-40277	0	1.0
NZ_LS483347_1	1.2\|658182\|33\|NZ_LS483347\|PILER-CR,CRT	658182-658214	33	MK448782	Streptococcus phage Javan501, complete genome	42595-42627	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448767	Streptococcus phage Javan467, complete genome	17252-17285	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448771	Streptococcus phage Javan481, complete genome	16777-16810	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	17357-17390	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448969	Streptococcus phage Javan514, complete genome	18500-18533	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448964	Streptococcus phage Javan502, complete genome	17082-17115	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448943	Streptococcus phage Javan450, complete genome	17252-17285	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448972	Streptococcus phage Javan520, complete genome	16625-16658	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448763	Streptococcus phage Javan451, complete genome	17403-17436	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448786	Streptococcus phage Javan509, complete genome	17252-17285	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448774	Streptococcus phage Javan487, complete genome	15613-15646	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448963	Streptococcus phage Javan498, complete genome	12874-12907	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448773	Streptococcus phage Javan485, complete genome	18499-18532	0	1.0
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448777	Streptococcus phage Javan491, complete genome	17285-17318	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448973	Streptococcus phage Javan522, complete genome	37440-37472	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448952	Streptococcus phage Javan472, complete genome	36430-36462	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448969	Streptococcus phage Javan514, complete genome	29538-29570	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	NC_004585	Streptococcus prophage 315.2, complete genome	36752-36784	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448966	Streptococcus phage Javan508, complete genome	36607-36639	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448972	Streptococcus phage Javan520, complete genome	31473-31505	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448795	Streptococcus phage Javan527, complete genome	42207-42239	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448679	Streptococcus phage Javan137, complete genome	34307-34339	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448959	Streptococcus phage Javan488, complete genome	37297-37329	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448774	Streptococcus phage Javan487, complete genome	29652-29684	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448772	Streptococcus phage Javan483, complete genome	36850-36882	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448778	Streptococcus phage Javan493, complete genome	37083-37115	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448773	Streptococcus phage Javan485, complete genome	32424-32456	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	NC_009819	Streptococcus phage P9, complete genome	35972-36004	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448954	Streptococcus phage Javan476, complete genome	35873-35905	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448950	Streptococcus phage Javan464, complete genome	36467-36499	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448957	Streptococcus phage Javan484, complete genome	41264-41296	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448975	Streptococcus phage Javan526, complete genome	37865-37897	0	1.0
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448764	Streptococcus phage Javan457, complete genome	28962-28994	0	1.0
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448685	Streptococcus phage Javan155, complete genome	21083-21116	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448942	Streptococcus phage Javan448, complete genome	11759-11792	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448969	Streptococcus phage Javan514, complete genome	22035-22068	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448964	Streptococcus phage Javan502, complete genome	20616-20649	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448972	Streptococcus phage Javan520, complete genome	20161-20194	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448763	Streptococcus phage Javan451, complete genome	20928-20961	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448855	Streptococcus phage Javan150, complete genome	21291-21324	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448774	Streptococcus phage Javan487, complete genome	19148-19181	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448773	Streptococcus phage Javan485, complete genome	22034-22067	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448777	Streptococcus phage Javan491, complete genome	20810-20843	1	0.971
NZ_LS483347_1	1.1\|658116\|34\|NZ_LS483347\|PILER-CR,CRT	658116-658149	34	MK448853	Streptococcus phage Javan144, complete genome	21083-21116	1	0.971
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448845	Streptococcus phage Javan118, complete genome	18032-18065	1	0.971
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448686	Streptococcus phage Javan157, complete genome	37423-37455	1	0.97
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MK448951	Streptococcus phage Javan470, complete genome	35948-35980	1	0.97
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448845	Streptococcus phage Javan118, complete genome	21471-21505	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448973	Streptococcus phage Javan522, complete genome	39810-39843	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448942	Streptococcus phage Javan448, complete genome	24642-24675	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448965	Streptococcus phage Javan506, complete genome	40062-40095	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448970	Streptococcus phage Javan516, complete genome	44669-44702	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448959	Streptococcus phage Javan488, complete genome	39664-39697	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448778	Streptococcus phage Javan493, complete genome	39453-39486	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448963	Streptococcus phage Javan498, complete genome	30340-30373	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448949	Streptococcus phage Javan460, complete genome	40460-40493	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448975	Streptococcus phage Javan526, complete genome	40244-40277	1	0.971
NZ_LS483347_1	1.6\|658181\|34\|NZ_LS483347\|CRISPRCasFinder	658181-658214	34	MK448782	Streptococcus phage Javan501, complete genome	42594-42627	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448767	Streptococcus phage Javan467, complete genome	17252-17286	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448771	Streptococcus phage Javan481, complete genome	16777-16811	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	17357-17391	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448969	Streptococcus phage Javan514, complete genome	18500-18534	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448964	Streptococcus phage Javan502, complete genome	17082-17116	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448943	Streptococcus phage Javan450, complete genome	17252-17286	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448972	Streptococcus phage Javan520, complete genome	16625-16659	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448763	Streptococcus phage Javan451, complete genome	17403-17437	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448786	Streptococcus phage Javan509, complete genome	17252-17286	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448774	Streptococcus phage Javan487, complete genome	15613-15647	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448963	Streptococcus phage Javan498, complete genome	12874-12908	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448773	Streptococcus phage Javan485, complete genome	18499-18533	1	0.971
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448777	Streptococcus phage Javan491, complete genome	17285-17319	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448973	Streptococcus phage Javan522, complete genome	37440-37473	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448952	Streptococcus phage Javan472, complete genome	36430-36463	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448969	Streptococcus phage Javan514, complete genome	29538-29571	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	NC_004585	Streptococcus prophage 315.2, complete genome	36752-36785	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448966	Streptococcus phage Javan508, complete genome	36607-36640	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448972	Streptococcus phage Javan520, complete genome	31473-31506	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448795	Streptococcus phage Javan527, complete genome	42207-42240	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448679	Streptococcus phage Javan137, complete genome	34307-34340	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448959	Streptococcus phage Javan488, complete genome	37297-37330	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448774	Streptococcus phage Javan487, complete genome	29652-29685	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448772	Streptococcus phage Javan483, complete genome	36850-36883	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448778	Streptococcus phage Javan493, complete genome	37083-37116	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448773	Streptococcus phage Javan485, complete genome	32424-32457	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	NC_009819	Streptococcus phage P9, complete genome	35972-36005	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448954	Streptococcus phage Javan476, complete genome	35873-35906	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448950	Streptococcus phage Javan464, complete genome	36467-36500	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448957	Streptococcus phage Javan484, complete genome	41264-41297	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448975	Streptococcus phage Javan526, complete genome	37865-37898	1	0.971
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448764	Streptococcus phage Javan457, complete genome	28962-28995	1	0.971
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448685	Streptococcus phage Javan155, complete genome	17563-17596	2	0.941
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448855	Streptococcus phage Javan150, complete genome	17759-17792	2	0.941
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK448853	Streptococcus phage Javan144, complete genome	17563-17596	2	0.941
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448685	Streptococcus phage Javan155, complete genome	21083-21117	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448942	Streptococcus phage Javan448, complete genome	11759-11793	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448969	Streptococcus phage Javan514, complete genome	22035-22069	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448964	Streptococcus phage Javan502, complete genome	20616-20650	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448972	Streptococcus phage Javan520, complete genome	20161-20195	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448763	Streptococcus phage Javan451, complete genome	20928-20962	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448855	Streptococcus phage Javan150, complete genome	21291-21325	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448774	Streptococcus phage Javan487, complete genome	19148-19182	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448773	Streptococcus phage Javan485, complete genome	22034-22068	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448777	Streptococcus phage Javan491, complete genome	20810-20844	2	0.943
NZ_LS483347_1	1.5\|658115\|35\|NZ_LS483347\|CRISPRCasFinder	658115-658149	35	MK448853	Streptococcus phage Javan144, complete genome	21083-21117	2	0.943
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448845	Streptococcus phage Javan118, complete genome	18032-18066	2	0.943
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448686	Streptococcus phage Javan157, complete genome	37423-37456	2	0.941
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MK448951	Streptococcus phage Javan470, complete genome	35948-35981	2	0.941
NZ_LS483347_1	1.3\|658247\|34\|NZ_LS483347\|PILER-CR,CRT	658247-658280	34	MK449012	Streptococcus phage Javan94, complete genome	18489-18522	3	0.912
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448685	Streptococcus phage Javan155, complete genome	17563-17597	3	0.914
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448855	Streptococcus phage Javan150, complete genome	17759-17793	3	0.914
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK448853	Streptococcus phage Javan144, complete genome	17563-17597	3	0.914
NZ_LS483347_1	1.7\|658246\|35\|NZ_LS483347\|CRISPRCasFinder	658246-658280	35	MK449012	Streptococcus phage Javan94, complete genome	18489-18523	4	0.886
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	NC_004565	Clostridium tetani E88 plasmid pE88, complete sequence	18677-18709	5	0.848
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	NC_004565	Clostridium tetani E88 plasmid pE88, complete sequence	18677-18710	5	0.853
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MH327484	Marine virus AG-341-P01 Ga0172215_11 genomic sequence	25876-25908	8	0.758
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MH319757	Marine virus AG-345-O18 Ga0172273_11 genomic sequence	1031-1063	8	0.758
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	MN693728	Marine virus AFVG_250M561, complete genome	22101-22133	8	0.758
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MH327484	Marine virus AG-341-P01 Ga0172215_11 genomic sequence	25875-25908	9	0.735
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	MH319757	Marine virus AG-345-O18 Ga0172273_11 genomic sequence	1031-1064	9	0.735
NZ_LS483347_1	1.4\|658313\|33\|NZ_LS483347\|PILER-CR,CRT	658313-658345	33	NZ_CP031260	Klebsiella quasipneumoniae strain L22 plasmid pL22-3, complete sequence	50503-50535	10	0.697
NZ_LS483347_1	1.8\|658312\|34\|NZ_LS483347\|CRISPRCasFinder	658312-658345	34	NZ_CP031260	Klebsiella quasipneumoniae strain L22 plasmid pL22-3, complete sequence	50503-50536	10	0.706

1. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatgtcaaa	Protospacer
**********************************

2. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

3. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

4. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

5. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

6. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

7. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

8. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

9. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

10. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

11. spacer 1.2|658182|33|NZ_LS483347|PILER-CR,CRT matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 0, identity: 1.0

tccttaattaaatgtattactcgtacgagaata	CRISPR spacer
tccttaattaaatgtattactcgtacgagaata	Protospacer
*********************************

12. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

13. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

14. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

15. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

16. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

17. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

18. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

19. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

20. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

21. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

22. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

23. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

24. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 0, identity: 1.0

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaaggat	Protospacer
**********************************

25. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

26. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

27. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

28. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

29. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

30. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

31. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

32. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

33. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

34. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

35. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

36. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

37. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

38. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

39. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

40. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

41. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

42. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

43. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 0, identity: 1.0

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tcctctcatcatatcttttaaatctttaacatc	Protospacer
*********************************

44. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

45. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

46. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

47. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

48. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

49. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

50. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

51. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

52. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

53. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

54. spacer 1.1|658116|34|NZ_LS483347|PILER-CR,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 1, identity: 0.971

atcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
atcaatatctcctttaataatgattaatatcaaa	Protospacer
****************************.*****

55. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 1, identity: 0.971

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataactgatttttggttaaatgat	Protospacer
****************************** ***

56. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 1, identity: 0.97

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ccctctcatcatatcttttaaatctttaacatc	Protospacer
.********************************

57. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 1, identity: 0.97

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ccctctcatcatatcttttaaatctttaacatc	Protospacer
.********************************

58. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 1, identity: 0.971

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatgtcaaa	Protospacer
.**********************************

59. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

60. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

61. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

62. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

63. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

64. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

65. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

66. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

67. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

68. spacer 1.6|658181|34|NZ_LS483347|CRISPRCasFinder matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 1, identity: 0.971

ttccttaattaaatgtattactcgtacgagaata	CRISPR spacer
ctccttaattaaatgtattactcgtacgagaata	Protospacer
.*********************************

69. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

70. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

71. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

72. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

73. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

74. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

75. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

76. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

77. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

78. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

79. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

80. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

81. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 1, identity: 0.971

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaaggat	Protospacer
.**********************************

82. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

83. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

84. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

85. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

86. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

87. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

88. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

89. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

90. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

91. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

92. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

93. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

94. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

95. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to NC_009819 (Streptococcus phage P9, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

96. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

97. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

98. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

99. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

100. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 1, identity: 0.971

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ctcctctcatcatatcttttaaatctttaacatc	Protospacer
.*********************************

101. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 2, identity: 0.941

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataacagatttttggttaaatgat	Protospacer
*************** ************** ***

102. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 2, identity: 0.941

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataacagatttttggttaaatgat	Protospacer
*************** ************** ***

103. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 2, identity: 0.941

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatataacagatttttggttaaatgat	Protospacer
*************** ************** ***

104. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

105. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

106. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

107. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

108. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

109. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

110. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

111. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

112. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

113. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448777 (Streptococcus phage Javan491, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

114. spacer 1.5|658115|35|NZ_LS483347|CRISPRCasFinder matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 2, identity: 0.943

tatcaatatctcctttaataatgattaatgtcaaa	CRISPR spacer
catcaatatctcctttaataatgattaatatcaaa	Protospacer
.****************************.*****

115. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 2, identity: 0.943

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataactgatttttggttaaatgat	Protospacer
.****************************** ***

116. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448686 (Streptococcus phage Javan157, complete genome) position: , mismatch: 2, identity: 0.941

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
cccctctcatcatatcttttaaatctttaacatc	Protospacer
..********************************

117. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 2, identity: 0.941

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
cccctctcatcatatcttttaaatctttaacatc	Protospacer
..********************************

118. spacer 1.3|658247|34|NZ_LS483347|PILER-CR,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 3, identity: 0.912

tttttcggatataactgatttttggttaaaggat	CRISPR spacer
tttttcggatatcactgatttttggttaaatgtt	Protospacer
************ ***************** * *

119. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 3, identity: 0.914

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataacagatttttggttaaatgat	Protospacer
.*************** ************** ***

120. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448855 (Streptococcus phage Javan150, complete genome) position: , mismatch: 3, identity: 0.914

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataacagatttttggttaaatgat	Protospacer
.*************** ************** ***

121. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 3, identity: 0.914

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatataacagatttttggttaaatgat	Protospacer
.*************** ************** ***

122. spacer 1.7|658246|35|NZ_LS483347|CRISPRCasFinder matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 4, identity: 0.886

ttttttcggatataactgatttttggttaaaggat	CRISPR spacer
ctttttcggatatcactgatttttggttaaatgtt	Protospacer
.************ ***************** * *

123. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to NC_004565 (Clostridium tetani E88 plasmid pE88, complete sequence) position: , mismatch: 5, identity: 0.848

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tgcacctatcatatcttttaaatctttaatatc	Protospacer
* * *..**********************.***

124. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to NC_004565 (Clostridium tetani E88 plasmid pE88, complete sequence) position: , mismatch: 5, identity: 0.853

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ttgcacctatcatatcttttaaatctttaatatc	Protospacer
** * *..**********************.***

125. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MH327484 (Marine virus AG-341-P01 Ga0172215_11 genomic sequence) position: , mismatch: 8, identity: 0.758

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
atttaatatcttatcttttaaatctttaagatc	Protospacer
 ..*  .*** ****************** ***

126. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MH319757 (Marine virus AG-345-O18 Ga0172273_11 genomic sequence) position: , mismatch: 8, identity: 0.758

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
atttaatatcttatcttttaaatctttaagatc	Protospacer
 ..*  .*** ****************** ***

127. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to MN693728 (Marine virus AFVG_250M561, complete genome) position: , mismatch: 8, identity: 0.758

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
ttctctcatcatagcttctaaatcttctgggtc	Protospacer
*.*********** ***.********. . .**

128. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MH327484 (Marine virus AG-341-P01 Ga0172215_11 genomic sequence) position: , mismatch: 9, identity: 0.735

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
catttaatatcttatcttttaaatctttaagatc	Protospacer
. ..*  .*** ****************** ***

129. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to MH319757 (Marine virus AG-345-O18 Ga0172273_11 genomic sequence) position: , mismatch: 9, identity: 0.735

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
catttaatatcttatcttttaaatctttaagatc	Protospacer
. ..*  .*** ****************** ***

130. spacer 1.4|658313|33|NZ_LS483347|PILER-CR,CRT matches to NZ_CP031260 (Klebsiella quasipneumoniae strain L22 plasmid pL22-3, complete sequence) position: , mismatch: 10, identity: 0.697

tcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
attagtcatcatatcttttaaatcagtaaattg	Protospacer
 ..  *******************  ***  *

131. spacer 1.8|658312|34|NZ_LS483347|CRISPRCasFinder matches to NZ_CP031260 (Klebsiella quasipneumoniae strain L22 plasmid pL22-3, complete sequence) position: , mismatch: 10, identity: 0.706

ttcctctcatcatatcttttaaatctttaacatc	CRISPR spacer
tattagtcatcatatcttttaaatcagtaaattg	Protospacer
* ..  *******************  ***  *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36649 : 49035

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111688390.1\|36649_40375_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.7e-40	27.0
WP_009880323.1\|40608_42063_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_023610840.1\|42090_43113_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	9.0e-63	41.4
WP_023079049.1\|43280_43835_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-25	36.1
WP_085614048.1\|44018_45566_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	4.4e-45	52.4
WP_010921776.1\|45623_46748_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	7.7e-07	28.6
WP_076634015.1\|47000_48266_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_023079042.1\|48543_49035_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.4e-18	43.1

DBSCAN-SWA_2

88237 : 104581

Streptococcus_phage(66.67%)

integrase,tRNA,holin

attL 83611:83625|attR 99663:99677

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
83611:83625	attL	NA	NA	NA	NA
WP_002986585.1\|88237_88957_+	metal ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-15	26.8
WP_002987764.1\|88949_89765_+	metal ABC transporter permease	NA	NA	NA	NA
WP_002986580.1\|89804_90188_-	HIT family protein	NA	NA	NA	NA
WP_111688593.1\|90351_91497_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	1.9e-98	49.7
WP_011185066.1\|91813_91957_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_003058809.1\|92807_93575_-	helix-turn-helix domain-containing protein	Q76TK4	Streptococcus_pyogenes_phage	3.6e-72	83.1
WP_002992503.1\|93728_93935_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	2.4e-07	47.0
WP_002992502.1\|93968_94169_+	helix-turn-helix transcriptional regulator	A0A1S5SE31	Streptococcus_phage	3.4e-11	56.7
WP_011185070.1\|94189_94597_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	8.5e-49	68.7
WP_111688392.1\|94610_95240_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	9.5e-31	43.0
WP_021775546.1\|95484_95817_+	hypothetical protein	NA	NA	NA	NA
WP_021775572.1\|95813_96035_+	hypothetical protein	NA	NA	NA	NA
WP_021775551.1\|96037_96229_+	hypothetical protein	NA	NA	NA	NA
WP_003058810.1\|96240_96570_+	hypothetical protein	NA	NA	NA	NA
WP_000051914.1\|96572_96845_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	6.1e-19	60.0
WP_021775562.1\|96845_97703_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	1.5e-124	74.8
WP_021775541.1\|97671_99360_+	nucleoside triphosphatase	A0A1X9I717	Streptococcus_phage	1.1e-259	82.3
WP_000694576.1\|99646_99820_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	4.3e-10	59.6
99663:99677	attR	NA	NA	NA	NA
WP_168389368.1\|99825_99999_+	hypothetical protein	NA	NA	NA	NA
WP_021775557.1\|100000_100510_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.6e-28	62.5
WP_002992480.1\|100583_101072_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
WP_020905578.1\|101471_101834_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_020905579.1\|101808_102186_+	phage encoded transcriptional regulator, ArpU family	Q938L8	Temperate_phage	3.7e-14	41.7
WP_085613994.1\|102322_103063_+	hypothetical protein	NA	NA	NA	NA
WP_085613995.1\|103321_104581_-\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	9.0e-73	41.0

DBSCAN-SWA_3

348426 : 394460

Streptococcus_phage(81.63%)

portal,tail,terminase,capsid,holin,integrase,head

attL 351334:351351|attR 389892:389909

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002983122.1\|348426_348918_+	single-stranded DNA-binding protein	A0A286QNX2	Streptococcus_phage	1.7e-59	74.2
WP_002983142.1\|349082_349322_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_002983144.1\|349454_350111_-	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_002983147.1\|350242_351187_-	magnesium transporter CorA family protein	NA	NA	NA	NA
351334:351351	attL	NA	NA	NA	NA
WP_047149517.1\|351430_352528_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	1.7e-197	94.8
WP_047149516.1\|352703_353255_-	hypothetical protein	A7J267	Streptococcus_phage	9.0e-86	92.3
WP_047149515.1\|353265_353649_-	phage protein	A7J268	Streptococcus_phage	1.5e-68	98.4
WP_011184049.1\|353662_354013_-	helix-turn-helix transcriptional regulator	M1I9X0	Streptococcus_phage	1.2e-48	85.3
WP_001283052.1\|354653_354845_+	hypothetical protein	A7J270	Streptococcus_phage	7.3e-27	100.0
WP_047149514.1\|354865_355096_+	hypothetical protein	A7J271	Streptococcus_phage	6.5e-30	89.3
WP_047149513.1\|355183_355441_+	hypothetical protein	NA	NA	NA	NA
WP_023611037.1\|355469_355640_+	hypothetical protein	A7J273	Streptococcus_phage	2.9e-19	87.5
WP_047149512.1\|355632_355836_+	hypothetical protein	NA	NA	NA	NA
WP_047149511.1\|355832_356219_+	hypothetical protein	A7J274	Streptococcus_phage	4.0e-56	86.6
WP_030127426.1\|356364_356568_+	hypothetical protein	A7J276	Streptococcus_phage	3.7e-29	89.6
WP_030127427.1\|356655_356955_+	hypothetical protein	A7J277	Streptococcus_phage	3.7e-41	96.0
WP_011888943.1\|356954_358112_+	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_086934854.1\|358120_358684_+	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_111688400.1\|358726_360649_+	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	98.9
WP_111688401.1\|360653_363038_+	DNA primase	A7J282	Streptococcus_phage	2.6e-286	98.0
WP_023613183.1\|363404_363680_+	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	1.3e-45	97.8
WP_111688402.1\|363676_364999_+	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	2.8e-250	97.0
WP_011054883.1\|364999_365170_+	hypothetical protein	A7J285	Streptococcus_phage	3.1e-21	94.2
WP_011054882.1\|365162_365435_+	hypothetical protein	A7J287	Streptococcus_phage	5.7e-25	73.3
WP_011054881.1\|365567_365984_+	transcriptional regulator	A7J289	Streptococcus_phage	3.3e-72	99.3
WP_111688403.1\|366101_366524_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.1e-67	99.3
WP_011054879.1\|366513_367791_+\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	1.1e-246	100.0
WP_038433243.1\|367806_369339_+\|portal	phage portal protein	A7J292	Streptococcus_phage	4.5e-292	99.8
WP_032465703.1\|369298_370747_+\|capsid	minor capsid protein	A7J293	Streptococcus_phage	1.2e-278	99.8
WP_011054876.1\|370774_370963_+	hypothetical protein	A7J294	Streptococcus_phage	7.4e-24	100.0
WP_011888934.1\|370967_371234_+	hypothetical protein	Q938K9	Temperate_phage	2.9e-37	96.6
WP_011888933.1\|371395_371965_+	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.9e-83	100.0
WP_002983429.1\|371977_372865_+	hypothetical protein	A7J297	Streptococcus_phage	2.1e-161	100.0
WP_011888932.1\|372876_373233_+\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	7.9e-59	99.2
WP_011054872.1\|373243_373522_+	hypothetical protein	A7J299	Streptococcus_phage	1.9e-47	100.0
WP_011106640.1\|373518_373863_+	HK97 gp10 family phage protein	A7J2A0	Streptococcus_phage	5.1e-55	98.2
WP_011054870.1\|373866_374226_+	hypothetical protein	A7J2A1	Streptococcus_phage	1.2e-57	98.3
WP_011054869.1\|374237_374837_+\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	1.7e-90	97.1
WP_011888931.1\|374890_375346_+	hypothetical protein	A7J2A3	Streptococcus_phage	5.3e-76	99.3
WP_011888930.1\|375420_375654_+	hypothetical protein	A7J2A4	Streptococcus_phage	1.3e-33	98.7
WP_111688404.1\|375668_380051_+	tape measure protein	A7J2A5	Streptococcus_phage	1.2e-225	74.2
WP_011054865.1\|380062_380905_+	hypothetical protein	A7J2A6	Streptococcus_phage	8.8e-157	97.9
WP_011888928.1\|380914_382894_+\|tail	phage tail protein	A7J2A7	Streptococcus_phage	0.0e+00	92.8
WP_011888927.1\|382890_384006_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-142	74.9
WP_011017395.1\|384020_385925_+	gp58-like family protein	Q938J9	Temperate_phage	1.1e-210	83.7
WP_002988448.1\|385936_386365_+	DUF1617 family protein	Q938J8	Temperate_phage	8.1e-58	84.3
WP_046735270.1\|386367_387006_+	hypothetical protein	A3F662	Streptococcus_phage	2.0e-44	52.7
WP_011017397.1\|387017_387290_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_029714020.1\|387286_387514_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.2e-30	97.3
WP_047149505.1\|387636_388842_+	glucosaminidase domain-containing protein	A7J2B5	Streptococcus_phage	1.5e-202	82.8
WP_047149504.1\|389538_389721_+	hypothetical protein	A3F673	Streptococcus_phage	1.7e-17	73.3
WP_032465207.1\|389947_392776_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.7e-306	55.7
389892:389909	attR	NA	NA	NA	NA
WP_023078663.1\|392890_393964_+	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	1.3e-16	32.2
WP_002988493.1\|393998_394460_+	hypothetical protein	F8WPT6	Bacillus_phage	1.1e-33	55.1

DBSCAN-SWA_4

554630 : 616545

Streptococcus_pyogenes_phage(56.45%)

tRNA,portal,tail,terminase,capsid,holin,integrase

attL 551570:551585|attR 621407:621422

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
551570:551585	attL	NA	NA	NA	NA
WP_085613764.1\|554630_555566_+\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.0e-05	38.5
WP_085613763.1\|555555_556878_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_002983660.1\|556915_557656_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_111688421.1\|557652_559551_+	Stk1 family PASTA domain-containing Ser/Thr kinase	B5LWE2	Feldmannia_species_virus	5.4e-21	30.3
WP_011054833.1\|559673_560366_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_002991890.1\|560362_561367_+	sensor histidine kinase	NA	NA	NA	NA
WP_002983671.1\|561359_562001_+	response regulator transcription factor	NA	NA	NA	NA
WP_085613761.1\|562037_563438_+	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	2.4e-26	43.5
WP_023610575.1\|563437_563815_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_085613760.1\|563832_564774_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	5.1e-129	76.9
WP_032465870.1\|564901_565534_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	1.9e-63	54.3
WP_076634161.1\|565589_566915_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	1.8e-116	51.1
WP_111688422.1\|566886_567552_+	ComF family protein	NA	NA	NA	NA
WP_002988974.1\|567631_568180_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_002983693.1\|575772_576306_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_009880741.1\|576385_577162_-	recombination regulator RecX	NA	NA	NA	NA
WP_009880742.1\|577309_578476_-\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	7.0e-80	42.2
WP_011018151.1\|578653_580075_-	DUF4041 domain-containing protein	M1PLF9	Streptococcus_phage	7.4e-140	74.5
WP_032463929.1\|580089_580476_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	8.3e-54	77.6
WP_011888679.1\|580459_580801_-	helix-turn-helix transcriptional regulator	J7KJZ4	Streptococcus_phage	1.2e-48	85.8
WP_014635614.1\|580998_581211_+	DNA-binding protein	J7KBP9	Streptococcus_phage	9.2e-31	95.7
WP_011018149.1\|581238_581958_+	phage antirepressor KilAC domain-containing protein	A0A141E1D3	Streptococcus_phage	2.8e-87	69.2
WP_021340237.1\|582367_582619_+	DNA-binding protein	A0A1P8VVV6	Streptococcus_phage	4.4e-40	96.4
WP_111688423.1\|582799_583114_+	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	5.9e-50	94.2
WP_009881060.1\|583127_583958_+	phage replisome organizer N-terminal domain-containing protein	A0A1S5S918	Streptococcus_phage	6.4e-67	54.7
WP_111688424.1\|583944_584727_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	4.6e-144	97.7
WP_011285580.1\|584717_584855_+	hypothetical protein	J7KBQ4	Streptococcus_phage	2.7e-07	78.4
WP_011285579.1\|584867_585221_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_021341161.1\|585201_585456_+	hypothetical protein	Q938N0	Temperate_phage	6.3e-42	97.6
WP_011018142.1\|585477_585960_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_111688425.1\|585960_586635_+	ERF family protein	Q938M8	Temperate_phage	8.4e-102	97.3
WP_011018140.1\|586627_587047_+	single-stranded DNA-binding protein	Q938M7	Temperate_phage	2.1e-71	99.3
WP_011106686.1\|587052_587256_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011018139.1\|587255_587696_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	1.6e-80	98.6
WP_111688426.1\|587692_588049_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	6.9e-55	91.5
WP_011018137.1\|588273_588558_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	2.7e-49	97.9
WP_111688427.1\|588554_588968_+	hypothetical protein	Q938M1	Temperate_phage	1.2e-34	62.4
WP_011017570.1\|588964_589249_+	hypothetical protein	A3F628	Streptococcus_phage	4.6e-33	79.8
WP_111688428.1\|589252_589735_+	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	1.4e-90	96.2
WP_172451638.1\|589724_590489_+	site-specific DNA-methyltransferase	A0A1S5SE41	Streptococcus_phage	1.6e-133	92.3
WP_032460172.1\|590536_590830_+	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	2.7e-49	99.0
WP_021340586.1\|591194_591632_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
WP_011285571.1\|592106_592487_+	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
WP_009880266.1\|592476_593751_+\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.1e-251	100.0
WP_009880265.1\|593750_595076_+\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	7.4e-243	100.0
WP_009880264.1\|595044_595953_+\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	4.2e-88	100.0
WP_011054805.1\|595959_596226_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.6e-38	100.0
WP_011054804.1\|596375_596948_+	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	1.2e-72	100.0
WP_111688430.1\|596965_597856_+\|capsid	phage capsid protein	A0A097PAW2	Streptococcus_pyogenes_phage	5.5e-85	98.8
WP_009880260.1\|597868_598162_+	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	2.0e-47	100.0
WP_009880259.1\|598175_598520_+	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.1e-54	100.0
WP_111688431.1\|598516_598828_+	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	1.0e-49	98.1
WP_009880257.1\|598824_599220_+	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	1.8e-59	100.0
WP_009880256.1\|599221_599632_+	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	1.4e-70	100.0
WP_009880255.1\|599643_600150_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	2.6e-79	100.0
WP_009880254.1\|600162_600480_+	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	4.9e-52	100.0
WP_009880253.1\|600452_600911_+	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	2.3e-82	100.0
WP_011054802.1\|600903_602709_+\|tail	tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	8.8e-263	99.7
WP_111688432.1\|602709_604194_+\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	1.3e-291	99.6
WP_011054801.1\|604194_607635_+\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	99.9
WP_111688433.1\|607639_609502_+	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	100.0
WP_009880247.1\|609512_609860_+	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	3.5e-59	100.0
WP_015055952.1\|610009_610333_+	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
WP_011054798.1\|610332_610665_+\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	5.7e-51	100.0
WP_011054797.1\|610666_611431_+	CHAP domain-containing protein	A0A097PAT3	Streptococcus_pyogenes_phage	1.5e-150	100.0
WP_111688434.1\|611442_612045_+	hypothetical protein	A0A097PAX9	Streptococcus_pyogenes_phage	1.3e-90	98.3
WP_011054795.1\|612055_612829_+	hypothetical protein	A0A097PAV0	Streptococcus_pyogenes_phage	3.9e-135	100.0
WP_009880241.1\|612838_613060_+	hypothetical protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
WP_009880240.1\|613059_613719_+	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	8.5e-123	100.0
WP_009880239.1\|613840_614596_-	streptococcal pyrogenic exotoxin SpeA	A0A097PAT7	Streptococcus_pyogenes_phage	2.2e-143	100.0
WP_011054793.1\|614816_614999_+	hypothetical protein	J7KBZ4	Streptococcus_phage	1.1e-19	81.4
WP_085613935.1\|615189_616545_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	2.3e-74	33.4
621407:621422	attR	NA	NA	NA	NA

DBSCAN-SWA_5

696904 : 805062

113

Streptococcus_phage(47.06%)

tRNA,portal,tail,terminase,capsid,protease,integrase,head

attL 719184:719203|attR 763943:763962

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_032465122.1\|696904_699706_+\|tRNA	isoleucine--tRNA ligase	H2EEZ0	Moumouvirus	1.4e-70	27.0
WP_002983878.1\|699970_700273_-	DUF1827 family protein	NA	NA	NA	NA
WP_085613970.1\|700323_700779_-	NUDIX hydrolase	NA	NA	NA	NA
WP_111688441.1\|700906_703189_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	1.4e-124	39.6
WP_002983885.1\|703486_703717_+	YkuJ family protein	NA	NA	NA	NA
WP_023610107.1\|703843_704530_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002989107.1\|704529_705264_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-34	38.8
WP_002993337.1\|705412_706822_+	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	5.7e-60	32.8
WP_002993334.1\|706999_708694_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.6e-128	42.4
WP_010922486.1\|708901_709756_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	2.0e-39	39.8
WP_085613971.1\|709908_711249_+	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	1.4e-39	30.9
WP_002983901.1\|711226_711442_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_111688442.1\|711441_712314_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_085613972.1\|712306_713134_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_014407685.1\|713120_713591_+	arginine repressor	NA	NA	NA	NA
WP_085613973.1\|713612_715274_+	DNA repair protein RecN	NA	NA	NA	NA
WP_085613974.1\|715445_716360_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002983913.1\|716575_717427_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_168393021.1\|717419_718262_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|718239_718827_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|718925_719201_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
719184:719203	attL	NA	NA	NA	NA
WP_111688443.1\|719290_720433_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	3.7e-174	77.6
WP_011285632.1\|720556_720823_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_002994744.1\|720834_721215_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	8.0e-41	61.1
WP_011285631.1\|721218_721566_-	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	3.6e-40	71.8
WP_020837421.1\|721988_722084_-	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002993390.1\|722719_722911_+	hypothetical protein	A7J270	Streptococcus_phage	4.0e-25	92.1
WP_011285630.1\|722922_723639_+	phage antirepressor KilAC domain-containing protein	C9WB91	Streptococcus_virus	6.8e-118	87.7
WP_010922204.1\|723670_723937_+	hypothetical protein	A0A1S5SC19	Streptococcus_phage	1.1e-23	66.3
WP_011285629.1\|723871_724678_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	7.9e-123	82.1
WP_011284879.1\|724819_725059_-	hypothetical protein	NA	NA	NA	NA
WP_011054585.1\|725225_725411_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_047149513.1\|725487_725745_+	hypothetical protein	NA	NA	NA	NA
WP_023611037.1\|725773_725944_+	hypothetical protein	A7J273	Streptococcus_phage	2.9e-19	87.5
WP_047149512.1\|725936_726140_+	hypothetical protein	NA	NA	NA	NA
WP_047149511.1\|726136_726523_+	hypothetical protein	A7J274	Streptococcus_phage	4.0e-56	86.6
WP_030127426.1\|726668_726872_+	hypothetical protein	A7J276	Streptococcus_phage	3.7e-29	89.6
WP_030127427.1\|726959_727259_+	hypothetical protein	A7J277	Streptococcus_phage	3.7e-41	96.0
WP_011888943.1\|727258_728416_+	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_086934854.1\|728424_728988_+	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_111688400.1\|729030_730953_+	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	98.9
WP_111688444.1\|730957_733342_+	DNA primase	A7J282	Streptococcus_phage	1.7e-277	94.8
WP_011054885.1\|733727_734003_+	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	2.9e-45	96.7
WP_111688445.1\|733999_735322_+	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	1.3e-250	97.3
WP_164972002.1\|735322_735493_+	hypothetical protein	A7J285	Streptococcus_phage	9.0e-21	92.3
WP_011054882.1\|735485_735758_+	hypothetical protein	A7J287	Streptococcus_phage	5.7e-25	73.3
WP_011054881.1\|735890_736307_+	transcriptional regulator	A7J289	Streptococcus_phage	3.3e-72	99.3
WP_111688446.1\|736397_736850_+\|terminase	terminase small subunit	A7J290	Streptococcus_phage	1.8e-63	91.4
WP_111688447.1\|736827_738135_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	9.0e-185	76.0
WP_002984369.1\|738146_739649_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
WP_002988386.1\|739629_741192_+\|head	phage head morphogenesis protein	U6E9F1	Streptococcus_phage	1.6e-47	44.2
WP_002988389.1\|741195_741381_+	hypothetical protein	NA	NA	NA	NA
WP_011284859.1\|741450_741765_+	hypothetical protein	M1PLI3	Streptococcus_phage	6.8e-38	72.8
WP_032462876.1\|741767_742034_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	6.6e-26	71.6
WP_014635511.1\|742177_742711_+	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.2e-15	84.2
WP_063632936.1\|742720_743101_+	hypothetical protein	NA	NA	NA	NA
WP_023078263.1\|743103_744186_+\|capsid	major capsid protein	A0A2H4J022	uncultured_Caudovirales_phage	2.2e-104	56.9
WP_011284854.1\|744195_744438_+	hypothetical protein	NA	NA	NA	NA
WP_002984392.1\|744451_744805_+\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	9.7e-25	49.6
WP_002984393.1\|744801_745110_+	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	5.7e-13	40.2
WP_038432514.1\|745090_745456_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	3.1e-18	47.9
WP_014635506.1\|745452_745842_+	hypothetical protein	Q8LTQ5	Lactococcus_phage	2.2e-46	69.8
WP_080465176.1\|745896_746502_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	2.1e-43	53.0
WP_023605140.1\|746554_746914_+	hypothetical protein	D7RWD6	Brochothrix_phage	1.5e-20	45.5
WP_111681178.1\|746955_747285_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	4.3e-11	40.6
WP_111688448.1\|747299_750935_+	tape measure protein	U6E979	Streptococcus_phage	5.2e-04	29.6
WP_032461961.1\|750966_751746_+\|tail	phage tail family protein	A3F655	Streptococcus_phage	2.1e-64	54.0
WP_111688449.1\|751742_753791_+\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	84.0
WP_111688450.1\|753790_754804_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.1e-181	97.9
WP_111688451.1\|754818_756705_+	gp58-like family protein	Q938J9	Temperate_phage	3.1e-218	84.7
WP_111688452.1\|756716_757145_+	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	88.6
WP_023611372.1\|757147_757780_+	hypothetical protein	Q938J7	Temperate_phage	2.6e-44	50.0
WP_023078532.1\|757790_758087_+	hypothetical protein	Q938J6	Temperate_phage	2.9e-46	99.0
WP_011054731.1\|758083_758269_+	hypothetical protein	Q938J5	Temperate_phage	1.7e-25	100.0
WP_111688453.1\|758379_758937_+	glycoside hydrolase family 73 protein	A7J2B5	Streptococcus_phage	6.5e-92	85.9
WP_011017838.1\|761480_762194_+	streptococcal pyrogenic exotoxin SpeM	Q938J1	Temperate_phage	6.9e-78	59.8
WP_011054727.1\|762669_763245_+	hypothetical protein	Q938J0	Temperate_phage	1.7e-111	100.0
WP_063632461.1\|763590_763773_+	hypothetical protein	A3F673	Streptococcus_phage	8.2e-20	78.3
WP_020837373.1\|764303_766166_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.4e-90	33.8
763943:763962	attR	NA	NA	NA	NA
WP_021299339.1\|766465_767401_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	4.6e-66	45.1
WP_002983928.1\|767639_768335_+	phosphoglycerate mutase	NA	NA	NA	NA
WP_002983930.1\|768442_768964_+	transcription repressor NadR	NA	NA	NA	NA
WP_002989140.1\|769124_769667_+	hypothetical protein	NA	NA	NA	NA
WP_002989141.1\|769790_770570_+	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_002983939.1\|771367_771964_+	recombination protein RecR	NA	NA	NA	NA
WP_023078843.1\|772064_773111_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_023078853.1\|773309_774701_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_011017956.1\|774780_775476_+	TIGR02206 family membrane protein	NA	NA	NA	NA
WP_111688455.1\|775723_777268_+	peptide chain release factor 3	A0A1B0RXH7	Streptococcus_phage	1.1e-35	29.1
WP_002989158.1\|777574_779194_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.9e-59	36.5
WP_085613978.1\|779321_781322_+	potassium transporter Kup	M1IBC2	Acanthocystis_turfacea_Chlorella_virus	5.8e-66	34.0
WP_002989164.1\|781345_781624_-	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	1.8e-05	36.0
WP_168393619.1\|781613_782468_-\|tRNA	tRNA1(Val) (adenine(37)-N6)-methyltransferase	NA	NA	NA	NA
WP_021299345.1\|782507_783248_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_002995626.1\|783447_784110_+	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_085613979.1\|784090_786334_+	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	8.8e-55	58.7
WP_011888795.1\|786404_787445_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_023078860.1\|787541_788147_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.3e-58	53.7
WP_023078840.1\|788313_788496_+	hypothetical protein	NA	NA	NA	NA
WP_023078847.1\|788524_788773_+	hypothetical protein	NA	NA	NA	NA
WP_085613980.1\|789460_790681_-	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_085613981.1\|790687_791716_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_085613982.1\|791917_792622_+	glucosamine-6-phosphate deaminase	NA	NA	NA	NA
WP_085613983.1\|792740_793457_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_085613984.1\|793751_794714_+	competence protein CoiA	NA	NA	NA	NA
WP_085613985.1\|794726_796532_+	oligoendopeptidase F	NA	NA	NA	NA
WP_002995765.1\|796907_798104_+	OFA family MFS transporter	NA	NA	NA	NA
WP_002989211.1\|798169_798877_+	O-methyltransferase	A0A2P1JQT7	Mycobacterium_phage	2.6e-08	27.2
WP_085613986.1\|798939_799995_+	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_085613987.1\|800381_803000_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	6.7e-62	33.9
WP_023078838.1\|803359_803575_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002995753.1\|803571_804333_+	DUF3169 family protein	NA	NA	NA	NA
WP_076634494.1\|804351_805062_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

869319 : 950618

Streptococcus_phage(41.54%)

tRNA,portal,tail,terminase,capsid,holin,integrase,head

attL 872682:872741|attR 917162:917260

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076634262.1\|869319_871584_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
WP_002989605.1\|871840_872461_-	DUF3862 domain-containing protein	NA	NA	NA	NA
872682:872741	attL	NA	NA	NA	NA
WP_011017891.1\|872822_873911_-\|integrase	site-specific integrase	Q38159	Streptococcus_phage	4.2e-204	99.4
WP_002984270.1\|874159_874969_-	type II toxin-antitoxin system PemK/MazF family toxin	J7KDP1	Streptococcus_phage	3.8e-24	35.8
WP_011284884.1\|874981_875725_-	helix-turn-helix domain-containing protein	A0A1S5S8T5	Streptococcus_phage	2.5e-75	62.9
WP_021340643.1\|876083_876233_+	hypothetical protein	J7KH12	Streptococcus_phage	4.3e-19	91.8
WP_021341080.1\|876218_876434_-	hypothetical protein	J7KBX0	Streptococcus_phage	2.5e-28	95.7
WP_011284883.1\|876492_876651_+	hypothetical protein	J7KH24	Streptococcus_phage	8.4e-21	90.4
WP_011284882.1\|876680_877280_-	hypothetical protein	A0A097PAT4	Streptococcus_pyogenes_phage	3.1e-108	100.0
WP_011284881.1\|877333_877543_+	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	1.7e-32	100.0
WP_011054589.1\|877531_877918_-	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	1.2e-65	100.0
WP_002984281.1\|877991_878219_+	hypothetical protein	A0A141E1R7	Streptococcus_phage	2.9e-14	57.3
WP_011017884.1\|878326_878836_-	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|879094_879304_-	hypothetical protein	NA	NA	NA	NA
WP_011284879.1\|879453_879693_-	hypothetical protein	NA	NA	NA	NA
WP_011054585.1\|879859_880045_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011017882.1\|880123_880420_+	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_002984309.1\|880416_880554_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	4.9e-17	97.8
WP_002984312.1\|880634_880964_+	hypothetical protein	A1EAC2	Streptococcus_phage	2.7e-13	41.6
WP_002984315.1\|880963_881158_+	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_002984318.1\|881154_881439_+	hypothetical protein	NA	NA	NA	NA
WP_002984321.1\|881435_882119_+	AAA family ATPase	J7KC09	Streptococcus_phage	9.4e-125	99.1
WP_075340263.1\|882154_883558_+	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.3
WP_002984328.1\|883562_884045_+	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	9.7e-60	70.7
WP_111688459.1\|884062_885616_+	phage resistance protein	A0A1P8BM51	Lactococcus_phage	2.8e-209	70.2
WP_020833541.1\|885882_886752_+	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	9.8e-103	65.2
WP_002984338.1\|886705_887056_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.6e-46	89.4
WP_111688460.1\|887039_887396_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.6e-54	90.7
WP_020833538.1\|887620_887896_+	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	2.9e-32	73.6
WP_020833537.1\|887892_888162_+	hypothetical protein	Q938M2	Temperate_phage	1.8e-39	88.8
WP_020833536.1\|888171_888552_+	hypothetical protein	A3F627	Streptococcus_phage	2.6e-36	63.5
WP_011018134.1\|888548_888833_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	8.9e-37	87.2
WP_010922070.1\|888834_889470_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_011284866.1\|889743_890178_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	6.2e-74	97.9
WP_011284864.1\|890755_891670_+	hypothetical protein	NA	NA	NA	NA
WP_002990048.1\|891759_891972_-	hypothetical protein	NA	NA	NA	NA
WP_002987543.1\|892287_892665_-	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_001132273.1\|892716_892902_-	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_047235590.1\|892964_893432_+\|terminase	terminase small subunit	A0A141E1Y3	Streptococcus_phage	1.9e-52	70.8
WP_020833530.1\|893409_894717_+\|terminase	PBSX family phage terminase large subunit	A0A2H4IYR5	uncultured_Caudovirales_phage	2.0e-184	75.7
WP_002984369.1\|894728_896231_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	1.9e-141	54.5
WP_111688462.1\|896211_897225_+\|capsid	minor capsid protein	O80166	Streptococcus_virus	3.6e-48	44.2
WP_011184918.1\|897169_897775_+	phage protein	NA	NA	NA	NA
WP_002988389.1\|897778_897964_+	hypothetical protein	NA	NA	NA	NA
WP_111688463.1\|898349_898616_+	hypothetical protein	Q938K9	Temperate_phage	1.2e-35	94.3
WP_002992590.1\|898759_899293_+	DUF4355 domain-containing protein	A0A141E0S7	Streptococcus_phage	1.8e-14	82.5
WP_111688464.1\|899302_899683_+\|head	head decoration protein	A0A286QRN6	Streptococcus_phage	1.1e-10	37.8
WP_111688465.1\|899685_900768_+\|capsid	major capsid protein	A0A2H4J022	uncultured_Caudovirales_phage	5.0e-104	56.6
WP_111688466.1\|900777_901020_+	hypothetical protein	NA	NA	NA	NA
WP_111688467.1\|901033_901387_+\|head,tail	phage head-tail connector protein	O80172	Streptococcus_virus	1.1e-25	49.6
WP_002984393.1\|901383_901692_+	hypothetical protein	A0A2P1JTW8	Anoxybacillus_phage	5.7e-13	40.2
WP_002984399.1\|901672_902038_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	7.7e-17	46.3
WP_020833525.1\|902034_902424_+	hypothetical protein	B5SP36	Lactococcus_phage	8.4e-46	69.0
WP_168640736.1\|902433_903123_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	4.5e-42	52.2
WP_002990023.1\|903176_903530_+	hypothetical protein	Q77RZ7	Lactococcus_phage	5.5e-20	48.6
WP_002988428.1\|903571_903901_+	hypothetical protein	A0A1P8BLR3	Lactococcus_phage	5.7e-11	40.6
WP_111688468.1\|903915_907551_+	tape measure protein	U6E979	Streptococcus_phage	4.0e-04	28.0
WP_011184914.1\|907583_908363_+\|tail	phage tail family protein	A3F655	Streptococcus_phage	1.7e-66	54.8
WP_111688469.1\|908359_910411_+\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	86.8
WP_010922091.1\|910407_911421_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.0e-184	99.7
WP_111688470.1\|911435_913319_+	gp58-like family protein	Q938J9	Temperate_phage	2.3e-250	96.3
WP_002987513.1\|913330_913762_+	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_032461328.1\|913764_914382_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.7e-77	88.8
WP_111688471.1\|914391_914664_+	hypothetical protein	A7J2B2	Streptococcus_phage	4.2e-36	91.0
WP_003058873.1\|914660_914888_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_111688472.1\|915003_916206_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	2.9e-238	98.0
WP_032461628.1\|916901_917090_+	hypothetical protein	A3F673	Streptococcus_phage	6.5e-20	81.4
WP_002989607.1\|917680_918295_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
917162:917260	attR	NA	NA	NA	NA
WP_023078569.1\|918427_919213_-	hypothetical protein	NA	NA	NA	NA
WP_023078568.1\|919222_919921_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	5.1e-09	27.3
WP_002989617.1\|919920_920292_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023078571.1\|920476_923587_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	3.7e-120	29.9
WP_010922375.1\|923666_924680_+	6-phosphofructokinase	NA	NA	NA	NA
WP_002984447.1\|924742_926245_+	pyruvate kinase	NA	NA	NA	NA
WP_002984449.1\|926462_927020_+	signal peptidase I	NA	NA	NA	NA
WP_011284834.1\|927195_929010_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-97	38.7
WP_002989626.1\|929205_929541_+	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002992417.1\|929647_930289_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002989632.1\|930298_930928_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-27	35.5
WP_002989634.1\|930943_931780_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_085613822.1\|932148_932922_+	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_020833513.1\|933291_934527_-	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_002984465.1\|934646_935969_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_011284831.1\|936497_938816_+	DNA helicase PcrA	A7KV33	Bacillus_phage	2.7e-131	41.2
WP_002984469.1\|939179_939428_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002989652.1\|939464_940076_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984473.1\|940086_940275_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984475.1\|940287_940827_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984476.1\|940867_941068_+	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
WP_002994467.1\|941078_941567_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984480.1\|941729_942371_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_085613823.1\|942513_943056_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_085613824.1\|943173_943875_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.4e-36	37.0
WP_002989667.1\|943889_946526_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_002993908.1\|946617_947214_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_002989673.1\|947224_948181_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_111688473.1\|948277_949618_+	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_111688474.1\|949733_950618_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA

DBSCAN-SWA_7

1264275 : 1274895

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085613704.1\|1264275_1265418_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
WP_012560601.1\|1265652_1266093_+	hypothetical protein	NA	NA	NA	NA
WP_085613705.1\|1266122_1267391_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_111688490.1\|1267478_1268831_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	2.0e-30	24.2
WP_023080164.1\|1269051_1269393_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
WP_085613707.1\|1269453_1270620_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002985140.1\|1270713_1271400_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985142.1\|1271413_1272577_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_011054348.1\|1272684_1274895_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.1

DBSCAN-SWA_8

1843308 : 1852733

Streptococcus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000051914.1\|1843308_1843581_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	6.1e-19	60.0
WP_111688577.1\|1843581_1844448_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	3.6e-121	73.1
WP_001069294.1\|1846147_1846402_+	hypothetical protein	NA	NA	NA	NA
WP_000694576.1\|1846398_1846572_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	4.3e-10	59.6
WP_168389368.1\|1846577_1846751_+	hypothetical protein	NA	NA	NA	NA
WP_021775557.1\|1846752_1847262_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.6e-28	62.5
WP_002992480.1\|1847335_1847824_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.4e-45	54.9
WP_020905578.1\|1848223_1848586_+	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_111688579.1\|1848560_1848944_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.3e-14	40.9
WP_021775534.1\|1849148_1849781_+	hypothetical protein	NA	NA	NA	NA
WP_085613591.1\|1850177_1852733_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	1.2e-42	23.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483347

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection