CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483349	Streptococcus mutans strain NCTC10449 chromosome 1	2 crisprs	DEDDh,cas3,WYL,cas5,cas8c,cas7,cas4,cas2,csa3,cas9,cas1,csn2,DinG,csm6	0	7	3	0

1. NZ_LS483349

CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483349_1

• CRISPR_ID: NZ_LS483349_1
• CRISPR_location: 412076-412569
• CRISPR_type: TypeI
• Repeat_type: I-C
• Spacer_info: 7 spacers
• Cas_protein_info: cas2,cas4,cas7,cas8c,cas5,cas3,WYL

Consensus repeat of NZ_LS483349_1

Consensus_repeat	Method
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	PILER-CR
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	CRT

spacers of NZ_LS483349_1

>1.1|412108|34|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
TGCATTTGTTAGTTGATTATCTCGACCTGTCCCA
>1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
AATTTGAAATGTCTATCCAATCAGAAGATTTATCA
>1.3|412241|33|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
TACAGTGCGACTGACTGCAGTAATAAACACTAA
>1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
AGAGCTCGAAAAGAGCATAACTAACCCAACAACAA
>1.5|412373|33|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
ACTGAAAAAGAATTACCAAGCAGTAATCATTGA
>1.6|412438|33|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT
AAGATGGCTGGAATATGAAGGAGAGGTAGAAAG
>1.7|412503|35|NZ_LS483349|CRT
TTCAAAAAATCCTGAAATAAACACTTCTGGTTTTT

CRISPR arrays and Neighbor proteins around NZ_LS483349_1

CRISPR arrays

The CRISPR arrays of NZ_LS483349_1

>merge|NZ_LS483349|1|412076-412569|PILER-CR,CRISPRCasFinder,CRT
GTCGCACCCTTCACGGGTGCGTGGATTGAAATTGCATTTGTTAGTTGATTATCTCGACCTGTCCCAGTCGCACCCTTCACGGGTGCGTGGATTGAAATAATTTGAAATGTCTATCCAATCAGAAGATTTATCAGTCGCACCCTTCACGGGTGCGTGGATTGAAATTACAGTGCGACTGACTGCAGTAATAAACACTAAGTCGCACCCTTCACGGGTGCGTGGATTGAAATAGAGCTCGAAAAGAGCATAACTAACCCAACAACAAGTCGCACCCTTCACGGGTGCGTGGATTGAAATACTGAAAAAGAATTACCAAGCAGTAATCATTGAGTCGCACCCTTCACGGGTGCGTGGATTGAAATAAGATGGCTGGAATATGAAGGAGAGGTAGAAAGGTCGCACCCTTCACGGGTGCGTGGATTGAAATTTCAAAAAATCCTGAAATAAACACTTCTGGTTTTTGTCGCACCCTTTAAAGGTTGGGTTTGTTTTTT

>NZ_LS483349|1|1|412076-412502|PILER-CR
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TGCATTTGTTAGTTGATTATCTCGACCTGTCCCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AATTTGAAATGTCTATCCAATCAGAAGATTTATCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TACAGTGCGACTGACTGCAGTAATAAACACTAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AGAGCTCGAAAAGAGCATAACTAACCCAACAACAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	ACTGAAAAAGAATTACCAAGCAGTAATCATTGA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AAGATGGCTGGAATATGAAGGAGAGGTAGAAAG
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT

>NZ_LS483349|1|1|412076-412502|CRISPRCasFinder
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TGCATTTGTTAGTTGATTATCTCGACCTGTCCCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AATTTGAAATGTCTATCCAATCAGAAGATTTATCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TACAGTGCGACTGACTGCAGTAATAAACACTAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AGAGCTCGAAAAGAGCATAACTAACCCAACAACAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	ACTGAAAAAGAATTACCAAGCAGTAATCATTGA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AAGATGGCTGGAATATGAAGGAGAGGTAGAAAG
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT

>NZ_LS483349|1|1|412076-412569|CRT
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TGCATTTGTTAGTTGATTATCTCGACCTGTCCCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AATTTGAAATGTCTATCCAATCAGAAGATTTATCA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TACAGTGCGACTGACTGCAGTAATAAACACTAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AGAGCTCGAAAAGAGCATAACTAACCCAACAACAA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	ACTGAAAAAGAATTACCAAGCAGTAATCATTGA
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	AAGATGGCTGGAATATGAAGGAGAGGTAGAAAG
GTCGCACCCTTCACGGGTGCGTGGATTGAAAT	TTCAAAAAATCCTGAAATAAACACTTCTGGTTTTT
GTCGCACCCTTTAAAGGTTGGGTTTGTTTTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483349.1|WP_002280165.1|420358_421717_-|aspartate-kinase	unknown	unknown	gnl|CDD|236364
NZ_LS483349.1|WP_002263670.1|402120_402366_+|hypothetical-protein	unknown	unknown	gnl|CDD|350305
NZ_LS483349.1|WP_002262529.1|421815_422460_+|HAD-family-phosphatase	unknown	unknown	gnl|CDD|223710
NZ_LS483349.1|WP_002262531.1|423742_424177_+|MarR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
NZ_LS483349.1|WP_002263664.1|411634_411928_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NZ_LS483349.1|WP_002263669.1|402649_403624_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379100
NZ_LS483349.1|WP_002266866.1|424176_425154_+|ketoacyl-ACP-synthase-III	unknown	unknown	gnl|CDD|236475
NZ_LS483349.1|WP_002280166.1|426508_427429_+|ACP-S-malonyltransferase	unknown	unknown	gnl|CDD|223408
NZ_LS483349.1|WP_002262530.1|422621_423413_+|enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|180910
NZ_LS483349.1|WP_002263665.1|409932_410604_+|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl|CDD|224385
NZ_LS483349.1|WP_002280167.1|427443_428178_+|3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl|CDD|235500
NZ_LS483349.1|WP_002280402.1|403868_406277_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124
NZ_LS483349.1|WP_002268387.1|407120_409052_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl|CDD|273839
NZ_LS483349.1|WP_002263667.1|406377_407121_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl|CDD|273847
NZ_LS483349.1|WP_002262533.1|425213_425438_+|acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
NZ_LS483349.1|WP_002262534.1|425540_426506_+|enoyl-[acyl-carrier-protein]-reductase-FabK	unknown	unknown	gnl|CDD|132195
NZ_LS483349.1|WP_002268386.1|409055_409931_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl|CDD|274216
NZ_LS483349.1|WP_002280401.1|398453_401105_+|valine--tRNA-ligase	unknown	unknown	gnl|CDD|235582
NZ_LS483349.1|WP_002263672.1|401676_401982_+|hypothetical-protein	unknown	unknown	gnl|CDD|225215
NZ_LS483349.1|WP_002262537.1|428226_429459_+|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl|CDD|235987

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_LS483349.1|WP_002280402.1|403868_406277_+|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	7.7e-104	343.1	16.3
NZ_LS483349.1|WP_002263669.1|402649_403624_+|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	1.3e-16	55.8	0.5
NZ_LS483349.1|WP_002263667.1|406377_407121_+|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	2.3e-57	188.8	0.0
NZ_LS483349.1|WP_002268386.1|409055_409931_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	9.7e-122	400.2	3.5
NZ_LS483349.1|WP_002263664.1|411634_411928_+|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	4.4e-31	101.8	0.1
NZ_LS483349.1|WP_002268387.1|407120_409052_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	4.2e-108	357.0	8.6
NZ_LS483349.1|WP_002263665.1|409932_410604_+|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	8.2e-29	95.6	1.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LS483349.1|WP_002280165.1|420358_421717_-|aspartate-kinase	gnl|CDD|236364	PRK09034, PRK09034, aspartate kinase; Reviewed.	0
NZ_LS483349.1|WP_002263670.1|402120_402366_+|hypothetical-protein	gnl|CDD|350305	cd18738, PIN_VapC4-5_FitB-like, uncharacterized subgroup of the PIN_VapC4-5_FitB-like subfamily of the PIN domain superfamily. The PIN_VapC4-5_FitB-like subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC4 and VapC5 ribonuclease toxins of the VapBC toxin/antitoxin (TA) system, and Neisseria gonorrhoeae FitB toxin of the FitAB TA system. This subfamily belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	5.90037e-05
NZ_LS483349.1|WP_002262529.1|421815_422460_+|HAD-family-phosphatase	gnl|CDD|223710	COG0637, COG0637, Predicted phosphatase/phosphohexomutase [General function prediction only].	3.20316e-45
NZ_LS483349.1|WP_002262531.1|423742_424177_+|MarR-family-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.10415e-16
NZ_LS483349.1|WP_002263664.1|411634_411928_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.51524e-31
NZ_LS483349.1|WP_002263669.1|402649_403624_+|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.83777e-14
NZ_LS483349.1|WP_002266866.1|424176_425154_+|ketoacyl-ACP-synthase-III	gnl|CDD|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	7.93648e-174
NZ_LS483349.1|WP_002280166.1|426508_427429_+|ACP-S-malonyltransferase	gnl|CDD|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	4.78843e-126
NZ_LS483349.1|WP_002262530.1|422621_423413_+|enoyl-CoA-hydratase	gnl|CDD|180910	PRK07260, PRK07260, enoyl-CoA hydratase; Provisional.	4.69772e-179
NZ_LS483349.1|WP_002263665.1|409932_410604_+|CRISPR-associated-protein-Cas4	gnl|CDD|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	7.3791e-30
NZ_LS483349.1|WP_002280167.1|427443_428178_+|3-oxoacyl-[acyl-carrier-protein]-reductase	gnl|CDD|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	8.73214e-127
NZ_LS483349.1|WP_002280402.1|403868_406277_+|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	6.29954e-98
NZ_LS483349.1|WP_002268387.1|407120_409052_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl|CDD|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	3.77682e-102
NZ_LS483349.1|WP_002263667.1|406377_407121_+|type-I-C-CRISPR-associated-protein-Cas5	gnl|CDD|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.21553e-102
NZ_LS483349.1|WP_002262533.1|425213_425438_+|acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	8.86201e-18
NZ_LS483349.1|WP_002262534.1|425540_426506_+|enoyl-[acyl-carrier-protein]-reductase-FabK	gnl|CDD|132195	TIGR03151, enACPred_II, putative enoyl-[acyl-carrier-protein] reductase II. This oxidoreductase of the 2-nitropropane dioxygenase family (pfam03060) is commonly found in apparent operons with genes involved in fatty acid biosynthesis. Furthermore, this genomic context generally includes the fabG 3-oxoacyl-[ACP] reductase and lacks the fabI enoyl-[ACP] reductase.	5.13667e-168
NZ_LS483349.1|WP_002268386.1|409055_409931_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl|CDD|274216	TIGR02589, conserved_hypothetical_protein, CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csd2 protein of the Dvulg subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02590, the Csh2 protein of the Hmari CRISPR subtype.	1.35245e-147
NZ_LS483349.1|WP_002280401.1|398453_401105_+|valine--tRNA-ligase	gnl|CDD|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483349.1|WP_002263672.1|401676_401982_+|hypothetical-protein	gnl|CDD|225215	COG2336, MazE, Growth regulator [Signal transduction mechanisms].	1.3401e-07
NZ_LS483349.1|WP_002262537.1|428226_429459_+|beta-ketoacyl-ACP-synthase-II	gnl|CDD|235987	PRK07314, PRK07314, beta-ketoacyl-ACP synthase II.	0

Protein sequences

>NZ_LS483349.1|WP_002263664.1|411634_411928_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETVAGRKRLRHVAKLCVDYGQRVQHSVFECSVTPAEFVEIKNELSTIIDQESDSIRFYLLGKNWQNRVETMGRDDSYDPDVGILLL
>NZ_LS483349.1|WP_002263665.1|409932_410604_+|CRISPR-associated-protein-Cas4
MAYAEDDYLMLSGIQHFQFCKRQWGLIHIEQQWAENEATAHGQILHQKADNPYIREKRKDIITSRAMHVSSKTLGLYGILDVVEFHKDKNGVTLKGKRGKWLPRIVEYKRGKPKRDTRDIVQLVAQTICLEETFGCPIETGCLYYHSVNQKKVIEITEALRQEVFDLAGQMHYYYDNKIIDKAEYFKNCPLCSLVDICKPRLSKKSRNVANYIKRHVMSEESL
>NZ_LS483349.1|WP_002268386.1|409055_409931_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEQKIDFMVTVEVREANANGDPLSGNMPRTDAKDYGLMSDVSIKRKIRNRMQDMGQPIFVQARDRVDDCIYSLKQRLENKEFFDTVKEGSKKKKSVENFVKQINAEWLDVRSFGQVFAFDGYSAANVRGPVSISWAKSLEKVVTQSMQITKSTNSELNSKTELESSTMGTKHFVDYGVYVIKGSINPNFAEKTGFSDADAEIIKEVLVSLFENDASSARPEGSMRVREVFWFTHSNKLGNVSSARVFDLLEFDKEKQDKDSYEDYAIHLNQEELAEYEAKGLQVEIIEGL
>NZ_LS483349.1|WP_002268387.1|407120_409052_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDLFTSLLKAYEKAEEIGLVDQQTGDNPVLLPIYHDNKVIKNNDIYIEILLDNEGAFYKARKFEIGENVIFPVTYESSNRTSTKIAPHPIVDSWYYVMYSELRKEKHQRYLQNLDNWIIQTENNKVENFLKIIKKFVENPESVELVLNSAFGSDCQIQEEFVDNNGKIQEGSLIFGEKKQKIALKDIKLSFKILEFDGLRDVSVSNFNEMHHDFINYINNNSTEIGIGICNISGKEDRIIKNHRKPKGVFSNGKLISQNNKIAYLGDRFPNENASSDIIKIGYETSEKIHLMIKYLLENNNSHTWLGTSQYLINWFSDDLSNDSQLDIVKPEFDDLFEDDEEEKQVFIKPNEENKKIGSSFVRGQKLFSNNATYNIAILNENKGRIALKYFRQLQVSQLLKNLESWQENYSWEAKTKAGNYELKKTPTFNEIINAAYGVDRERYLELDNDSFRSDQYQQLVTALIDGKPLPNTIVKKLEDNIRQRQKYSKHWYQVQQVSLAVLQKQYGREFTPMLDHQETDRSYLFGRLLAIYELFEAQRYALDGSSQERVTNAERYWNAYTGQPAKMMTHLENKIKPYEEVLKLNKPGIWHKLEKERKEIIQLMTPMYAHKNFTQSLDYKFIFGYYAEKQFYYTKQAKENEE
>NZ_LS483349.1|WP_002263667.1|406377_407121_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRNFYARIRGDRALFTNPATKGGSERSSYSVPTRQALQGIIDGIYHKPTFTNVITEVKVVNQIQTELHGVRALLHDYSADLSYVSYLSDVEYLVKFHFIWNENREDLIQDRLPKKHEAIMERSIRKGGRRDIFLGTRECFGLVDEISQEEYETIPSYYNGVTIDLGIMFHSFAYPTSKDTPLKSYFTKTVMENGAIKFKPQSECEIVNTLSSYAFKSLGQLKSVDDEYVDDEYEEYEAMEKGEG
>NZ_LS483349.1|WP_002280402.1|403868_406277_+|CRISPR-associated-helicase/endonuclease-Cas3
MKMKLAHKNNTGEEQSLEDHSFNVANKAREDAEFIGQGDLLFLLGMFHDLGKADEKFQNKLTKNPTMHVDHAYAGAKYLYEKIKIRLSAKGVDKATRLQFNEIVAYVIAAHHGMFDIVDLESEQHAYNKLRNRIARPKSDYHFDSDVTNFANFLETKLEHYGYQDLGMLIDKSFENYQQALSKLDCQDSSEEVYYQSCFVRLYLSLLKNADILDTINAYGLLINPLKQEEKIRLNRSYLEAIEKKYGEFGSPTTRLNEIRSQIAERVKSRGESDSTGIYRLDLPTGAGKTNLSMRYAFHQLVDQDRSRFFYITPFLSVLEQNAAAIKKVIGEDGVLEHHSNVVQNKQENEDKGDEKESLLPEYLIESWDSPVVLTSMVQFFQTLFKTKSANIRRFSSLANSVLILDEVQSLPIEVTALFNLTMNFLNKVMNTTIILCTATQPAYDSTAIKHKLSYGGKYGEATDMVELTHDEKEVFSRTELRKFDETNQNSKLSDLVDFVLENDESILVIFNTKKTVDRFYSLLEKLTDRPIYQLSTNMCAQHRLDIISEIKQGLEDGLPLICISTQLIEAGVDVDFNHVIRSYAGIDSIVQASGRCNREGKRDKGQVTLINLTSEEENISPLKEIKAKKDATEYILHKISSPIDTSLLNRDFFEYYYANNQGSMDYPLEHDGESVYDYLSVNFYQKKVGFKGKLKQAFKTAGLKMNLINNETIGILVPYRDAAEKLLILEELCKSDYPSEEDYRAIKALLKELQSYTVNVREHNQILEATKPYLNGQIQILSDSYYDDKKGITLESASFLM
>NZ_LS483349.1|WP_002263669.1|402649_403624_+|WYL-domain-containing-protein
MAESKTKRLLYFMSELEKGNQINKEEYIAKFNISDRTMKEDVSELKTNLKELRPNMQIKFSRKHACYFASYEQGYGNLKYNQAVILSKILLESRALRKEEVAEIINIFVERAVDDKERTRIKKLTQFELNSYQELKFYQKSNKSILPTISAIFDAIVDQRPLAFSYTKPSSKVEEYIVLPISVIFDNHYFYCISYKLDNCFQSRYELQELRYFRVDRFKTIHKSISNSAFALTEEEQERLITDEQVRYQTFSMLSDQKWVRIQFRYTGQFRDVLEADIPKLKMINELEEGIIYEIETLSLLGFQKYIQRFDGDFVFLNIKSIKK
>NZ_LS483349.1|WP_002263670.1|402120_402366_+|hypothetical-protein
MGKIARLELEKLVKIFQVLDVTKENCLQALSMKMPDFEGAVVAAVALSNDINIVVTRNVTDFQDSELIIYLPEEFLERLKR
>NZ_LS483349.1|WP_002263672.1|401676_401982_+|hypothetical-protein
MAVLLEQDRIQLKKWGNSNAFRIPQKLLKSLKFEPDQEFTIKAVDLGGHKQLVIEPLVSQNDQLSLIESLSGILSDSETVDVKDYRSERKEERLKKYESLT
>NZ_LS483349.1|WP_002280401.1|398453_401105_+|valine--tRNA-ligase
MSTQLSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLPDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEARLAEDGISRYDLGREKFLDKVWEWKDEYAATIKEQWGKMGISVDYSRERFTLDEGLSKAVRKVFVELYKKGWIYRGEFIINWDPKARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVATTRPETMFGDTAVAVNPNDDRYKDLIGQNVILPIVNKLIPIVADEHADPEFGTGVVKITPAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKATVKKLEEIGALVEIEKMTHSVGHSERTGVPIEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNADGDMYVGEEAPEGDGWKQDEDVLDTWFSSALWPFSTMGWPDTDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFKNVLIHGLIRDEQGRKMSKSLGNGIDPMDVVDKYGADALRWFLSNGSAPGQDVRFSYEKMDAAWNFINKIWNISRYILMNNEGLSLDQASKNVVLVTNGKAGNVTDRWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSEDEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIFGQYADGSIVTAAYPTVNPAFENQTAHSGVESLKDLIRAVRNARAEVNVAPSKPITILVKTSDSNLEDFFKANVNYIKRFTNPETLEISSAIATPELAMSAVITGAEIFLPLADLLNVEEELARLNKELAKWQKELDIVAKKLSNDRFVQNAKPEIVQKERDKQIDYQTKYDATVERIKEMEKLIK
>NZ_LS483349.1|WP_002280165.1|420358_421717_-|aspartate-kinase
MKVVKFGGSSLASATQLEKVLNIIKSDEERRFVVVSAPGKRDAQDTKVTDALIRYYRSYTSDKDVTADQSWIINRYRAIIDELGLGQNILEKITKAIVDLANLPIEDNDFLYDTFLAAGEDNNAKLIAEYFRKNGLSARYIHPKKAGIIVTSEPGNARIIPSSYDKLEELRDSDEVLVIPGFFGVTIDNQICTFSRGGSDITGSIVAAGVKADLYENFTDVDGIFAAHPGVVHKPHSISELTYREMRELAYAGFSVLHDEALIPAYRGKIPLVIKNTNNPEHSGTKIVLAHTGATIPVVGIAGDDDFVSINLSKYLMNREIGFGRKVLQVLEELNIRWEHIPTGIDDMSIILRGRELTPIKEQEIISQLTRKLEVDEVEIERNLSIIMIVGENMKNHIGVTAKAAEAFSKKHINLEMISQGSSEVSVMFVIKTEQEKQAVRALYQTFFMKDE
>NZ_LS483349.1|WP_002262529.1|421815_422460_+|HAD-family-phosphatase
MATKAVIFDMDGVLFDTEGFYYRRREIFLNDKGISIKHIPPAFFIGGNMKQVWQKILEDDYANWDVEQLQKDYTSYKNKHPLPYQNLIFPDVKVILEKLKQHQFKIALASSSTKSDILLALNKTGIYDYFDLVLSGEEFPESKPHPAIYNEAAYQLGFPKSELLIIEDSEKGIAAGVSAGIEVWAIKDRTFGLNQRAASRLFSNLTEVVDFLLK
>NZ_LS483349.1|WP_002262530.1|422621_423413_+|enoyl-CoA-hydratase
MDFKEILYNVDNGVATLTLNRPEVSNGFNIPICEEILKAIDIAKKDDTVQILLINANGKVFSVGGDLVEMQRAVDADDVQSLVRIAELVNKISFALKRLPKPVVMSTDGAVAGAAANIAVAADFCIASDKTRFIQAFVNVGLAPDAGGLFLLTRAIGITRATQLAMTGEALNAEKALEYGIVYKVCEPEKLEKITDRVITRLKRGSVNSYKAIKEMVWQSSFAGWQEYEDLELELQKSLAFTNDFKEGVRAYTEKRRPKFTGK
>NZ_LS483349.1|WP_002262531.1|423742_424177_+|MarR-family-transcriptional-regulator
MDYKQINTYLVDIFNKIMIIEEMSLKTSQFNDVSLKEMHTVDIIGKNANVTPSDIAHELLVTLGTVTTSLNKLEKKGYIERTRSQLDRRVVYLTLTQKGRLLYRLHNRFHKNVVNRITEAMDATELGALEKGLRNLHQFLEGLV
>NZ_LS483349.1|WP_002266866.1|424176_425154_+|ketoacyl-ACP-synthase-III
MTFAKISQAAYYVPSQVVTNDDLSKIMDTSDEWITSRTGIRERRISQSEDTSDLASQVAKELLKKASLKAKEIDFIIVATITPDAMMPSTAACVQAKIGAVNAFAFDLTAACSGFIFALSAAEKMIKSGQYQKGLVIGAEVLSKIIDWSDRTTAVLFGDGAGGVLLEADSSEHFLFESIHSDGSRGESLTSGEHAVSSPFSQVDKKDNCFLKMDGRAIFDFAIRDVSKSISTLIRKSDMPVEAIDYFLLHQANIRILDKMAKKIGADREKFPANMMKYGNTSAASIPILLAECVENGTIELNGSHTVLLSGFGGGLTWGSLIVKI
>NZ_LS483349.1|WP_002262533.1|425213_425438_+|acyl-carrier-protein
MAVFEKVQEIIVEELGKDTDEVKLETTFDELDADSLDVFQVISEIEDEFDIQIESEDGLNTVGDLVAFVEEKTK
>NZ_LS483349.1|WP_002262534.1|425540_426506_+|enoyl-[acyl-carrier-protein]-reductase-FabK
MKTRITELLDIEYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEVVKANIDKIKAVTNKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKYIERFHEAGITVIPVVPSVALARRMEKLGADAVIAEGMEAGGHIGKLTTMTLVRQVVDAVNIPVIGAGGVADGRGAAAVFMLGAEAIQVGTRFAVAKESNAHANFKKKILKAKDIDTVISASIVGHPVRAIKNKLSSAYATAEKEFLRGEKSQEDIEVLGAGALRNAVVDGDVDNGSVMAGQIAGFVTKEETCEEILKDLYYGAAKVIKAEAARWADVEK
>NZ_LS483349.1|WP_002280166.1|426508_427429_+|ACP-S-malonyltransferase
MTKTAFLFAGQGTQKLGMASDLYEIYPVVKETFKTAHSILGYDVRALIDNDEEKLNQTRYAQPAILTTSVAIYRLLKEKGYQPDIVAGLSLGEYSSLVAAGAISFEDALALVAKRGEFMETAAPAGVGKMVAVMNTDPRLVEEICQKASSKGIVSPANYNTPTQIVIGGEVAAVDYAVELLKEAGSKRLISLKVSGPFHTALLKSASQKLAQALENIKFSDFTLPLVGNTEAEIMEEHEIKSLLARQVKEPVRFYESIAVMQKFGVNNYVEIGPGKVLSGFVKKIDKSAKISAVEDLASLQAFLDN
>NZ_LS483349.1|WP_002280167.1|427443_428178_+|3-oxoacyl-[acyl-carrier-protein]-reductase
MEIKNKNVFITGSTRGIGLAIAHKFAQAGANIVLNGRSEISQDLVVEFKDYGVKVATISGDVSHFEDAKRMVDEATEALGSVDILVNNAGITNDKLMLKMTEEDFERVLKINLTGSFNMTKAVLKPMTKARQGAIINMSSVVGLAGNVGQANYAASKAGLIGFTKAVAREVAARNVRVNAIAPGFIESEMTERIPDKMKDAMLNQIPMKTFGKTENVAEVAIFLAQQDYLTGQVIAIDGGMTMQ
>NZ_LS483349.1|WP_002262537.1|428226_429459_+|beta-ketoacyl-ACP-synthase-II
MTLKRVVVTGYGVTSPIGHTPEDFWNSLHDGKIGIKPITKFDASEIPVFNAGEIQDFPFDKYFVKKDKNRMDTYSLYAIYAAMEAIENAALDMAQEIRDRVGVIVSSGIGGLQELEDQIIRMHERGMKRIKPMFIPKALSNMGAGNIALKIGAQGVCKSITTACASANDAIGEAFREIKYGFHDVILAGGSEASITKIGIGGFNALTALSTTEDPARSAIPFDKDRNGFVMGEGAAVLILESLEHAQKRGARILAEVVGYGSNCDAYHMTTPTPDGSGAAKAIKLAINEAGISPEEVNYVNAHGTSTQANEKGESKAIVAVLGKDVPVSSTKSFTGHLLGAAGGVEAIATIEAIRNHFVPMTAGTKELSEDIEANVVYGQGQEADIKYAISNTFGFGGHNAVLAFKRWED

Crispr_ID: NZ_LS483349_2

• CRISPR_ID: NZ_LS483349_2
• CRISPR_location: 741870-742103
• CRISPR_type: TypeII
• Repeat_type: II-A,II-B
• Spacer_info: 3 spacers
• Cas_protein_info: csn2,cas2,cas1,cas9

Consensus repeat of NZ_LS483349_2

Consensus_repeat	Method
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAA	CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CRT

spacers of NZ_LS483349_2

>2.1|741905|31|NZ_LS483349|CRISPRCasFinder
CGAAAAGCCAGCTCAAGACGATAATCTTGAG
>2.2|741971|31|NZ_LS483349|CRISPRCasFinder
CCTGTTAATTCAAACTCATGTAACACAGGCT
>2.3|741906|30|NZ_LS483349|CRT
GAAAAGCCAGCTCAAGACGATAATCTTGAG
>2.4|741972|30|NZ_LS483349|CRT
CTGTTAATTCAAACTCATGTAACACAGGCT
>2.5|742038|30|NZ_LS483349|CRT
CGGCATATATAATCCGTAAAGGCGGCACAT

CRISPR arrays and Neighbor proteins around NZ_LS483349_2

CRISPR arrays

The CRISPR arrays of NZ_LS483349_2

>merge|NZ_LS483349|2|741870-742103|CRISPRCasFinder,CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACGAAAAGCCAGCTCAAGACGATAATCTTGAGGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAACCTGTTAATTCAAACTCATGTAACACAGGCTGTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAATCGGCATATATAATCCGTAAAGGCGGCACATGTTTTAGAGCCATGTTAGTTACTGATTTACTAAAAC

>NZ_LS483349|2|2|741870-742036|CRISPRCasFinder
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAA	CGAAAAGCCAGCTCAAGACGATAATCTTGAG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAA	CCTGTTAATTCAAACTCATGTAACACAGGCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAA

>NZ_LS483349|2|2|741870-742103|CRT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	GAAAAGCCAGCTCAAGACGATAATCTTGAG
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAC	CTGTTAATTCAAACTCATGTAACACAGGCT
GTTTTAGAGCTGTGTTGTTTCGAATGGTTCCAAAAT	CGGCATATATAATCCGTAAAGGCGGCACAT
GTTTTAGAGCCATGTTAGTTACTGATTTACTAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483349.1|WP_002280230.1|735136_739174_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226044
NZ_LS483349.1|WP_002269450.1|741338_741716_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl|CDD|374224
NZ_LS483349.1|WP_002269623.1|750363_751020_-|Pr6Pr-family-membrane-protein	unknown	unknown	unknown
NZ_LS483349.1|WP_002264337.1|751338_752979_+|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl|CDD|236471
NZ_LS483349.1|WP_002280228.1|732903_733770_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197666
NZ_LS483349.1|WP_002270553.1|749690_750299_+|hypothetical-protein	unknown	unknown	unknown
NZ_LS483349.1|WP_002263547.1|740036_740381_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NZ_LS483349.1|WP_002280227.1|731288_732779_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|180854
NZ_LS483349.1|WP_002279852.1|730103_731279_-|MFS-transporter	unknown	unknown	gnl|CDD|341026
NZ_LS483349.1|WP_002279995.1|748228_749056_+|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NZ_LS483349.1|WP_002265423.1|741129_741321_+|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl|CDD|377942
NZ_LS483349.1|WP_002280229.1|733889_734756_+|NADPH-dependent-oxidoreductase	unknown	unknown	gnl|CDD|377026
NZ_LS483349.1|WP_002262720.1|743394_743679_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197775
NZ_LS483349.1|WP_002263546.1|740370_741033_+|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl|CDD|213408
NZ_LS483349.1|WP_002279994.1|743841_745593_+|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl|CDD|369832
NZ_LS483349.1|WP_018110186.1|745722_745953_+|hypothetical-protein	unknown	unknown	unknown
NZ_LS483349.1|WP_002280231.1|739173_740040_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|187851
NZ_LS483349.1|WP_002262717.1|746364_748200_+|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NZ_LS483349.1|WP_002272311.1|742185_743079_-|LexA-family-transcriptional-regulator	unknown	unknown	gnl|CDD|119397
NZ_LS483349.1|WP_002268969.1|749134_749611_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NZ_LS483349.1|WP_002280230.1|735136_739174_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	0	1236.3	54.3
NZ_LS483349.1|WP_002263547.1|740036_740381_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	3.1e-52	170.5	0.9
NZ_LS483349.1|WP_002263546.1|740370_741033_+|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	2.2e-107	352.3	18.7
NZ_LS483349.1|WP_002280231.1|739173_740040_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	1.5e-103	340.4	3.7

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NZ_LS483349.1|WP_002280230.1|735136_739174_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl|CDD|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LS483349.1|WP_002269450.1|741338_741716_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl|CDD|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	2.66065e-14
NZ_LS483349.1|WP_002280228.1|732903_733770_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.57862e-21
NZ_LS483349.1|WP_002263547.1|740036_740381_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.02077e-50
NZ_LS483349.1|WP_002280227.1|731288_732779_-|FAD-dependent-oxidoreductase	gnl|CDD|180854	PRK07121, PRK07121, FAD-binding protein.	1.1902e-40
NZ_LS483349.1|WP_002279852.1|730103_731279_-|MFS-transporter	gnl|CDD|341026	cd17473, MFS_arabinose_efflux_permease_like, Putative arabinose efflux permease family transporters of the Major Facilitator Superfamily. This family includes a group of putative arabinose efflux permease family transporters, such as alpha proteobacterium quinolone resistance protein NorA (characterized Staphylococcus aureus Quinolone resistance protein NorA belongs to a different group), Desulfovibrio dechloracetivorans bacillibactin exporter, Vibrio aerogenes antiseptic resistance protein. The biological function of those transporters remain unclear. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.08633e-50
NZ_LS483349.1|WP_002279995.1|748228_749056_+|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.56832e-07
NZ_LS483349.1|WP_002265423.1|741129_741321_+|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl|CDD|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	3.38968e-15
NZ_LS483349.1|WP_002280229.1|733889_734756_+|NADPH-dependent-oxidoreductase	gnl|CDD|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	1.62593e-38
NZ_LS483349.1|WP_002262720.1|743394_743679_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	8.64754e-07
NZ_LS483349.1|WP_002263546.1|740370_741033_+|type-II-A-CRISPR-associated-protein-Csn2	gnl|CDD|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.55029e-116
NZ_LS483349.1|WP_002279994.1|743841_745593_+|LPXTG-cell-wall-anchor-domain-containing-protein	gnl|CDD|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	3.03812e-110
NZ_LS483349.1|WP_002264337.1|751338_752979_+|phosphoenolpyruvate-carboxykinase-(ATP)	gnl|CDD|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	6.26078e-12
NZ_LS483349.1|WP_002280231.1|739173_740040_+|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.53858e-128
NZ_LS483349.1|WP_002262717.1|746364_748200_+|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483349.1|WP_002272311.1|742185_743079_-|LexA-family-transcriptional-regulator	gnl|CDD|119397	cd06529, S24_LexA-like, Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.	1.55409e-23
NZ_LS483349.1|WP_002268969.1|749134_749611_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.55706e-16

Protein sequences

>NZ_LS483349.1|WP_002269450.1|741338_741716_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLKSYPAIFHKEEEGYWVEFPEFGGGTQGEDLEEAMKNARQMLESVLASYLDEGMKLPNPSEIRKLSVEDGFATMIQADPNPYLKNNKAIRKNVTVPEWLVQLADRDQVNYSEVLTKALEKKLQL
>NZ_LS483349.1|WP_002265423.1|741129_741321_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MPLTGKELARLAINNGWEEVRVRGSHHHFKKDGVPYIVTIPIHGNKVLKIGLEKKLLRDLNLL
>NZ_LS483349.1|WP_002263546.1|740370_741033_+|type-II-A-CRISPR-associated-protein-Csn2
MKLNFPILDEPITLEKSTILVLEDVQVFAQMVRNLYQYDEDSELKFFNRKFKSLKPSELMLVTDILGYDVNAPSLLKLVHADLENQFNEKPEVKSMVEKLANTITELIAYECLENELDLEYDEITILELIKALGVKIETQSDTIFEKMFEVLQVYKYLNKKKLLVFINTLSYFKREEIAQILEYIHLSDMVVLFLEPRKIDGFAQYILDEDYFLITESNN
>NZ_LS483349.1|WP_002263547.1|740036_740381_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANTAMIARLKENNPKKGNITLLTVTEKQFARMIYLNGERDTSIANSDSRLVFLGEAFPDET
>NZ_LS483349.1|WP_002280231.1|739173_740040_+|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLSYKNNHLIFKDTYQTEMIHLSEIDILLLETTDIVLSTMLVKRLVDENILLIFCDDKRLPTAMLMPYYARHDSSLQLNNQISWAEEVKCDVWTTIIAQKILNQSCYLGECSYFEKSQSIMDLYHDLEPFDPSNREGHSARIYFNTLFGNDFFREQDNDINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPIVDRIVYENRNNSFIKIKRELFSMFSDTYLYNNKEMYLTNIVSDYTKKVIKALNNDGKGVPEFRI
>NZ_LS483349.1|WP_002280230.1|735136_739174_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKPYSIGLDIGTNSVGWAVVTDDYKVPAKKMKVLGNTDKSHIKKNLLGALLFDSGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVTEDKRGERHPIFGNLEEEVKYHENFPTIYHLRQYLADNPEKVDLRLVYLALAHIIKFRGHFLIEGKFDTRNNDVQRLFQEFLAVYDNTFENSSLQEQNVQVEEILTDKISKSAKKDRVLKLFPNEKSNGRFAEFLKLIVGNQADFKKHFELEEKAPLQFSKDTYEEELEVLLAQIGDNYAELFLSAKKLYDSILLSGILTVTDVSTKAPLSASMIQRYNEHQMDLAQLKQFIRQKLSDKYNEVFSDVSKDGYAGYIDGKTNQEAFYKYLKGLLNKIEGSGYFLDKIEREDFLRKQRTFDNGSIPHQIHLQEMRAIIRRQAEFYPFLADNQDRIEKILTFRIPYYVGPLARGKSDFAWLSRKSADKITPWNFDEIVDKESSAEAFINRMTNYDLYLPNQKVLPKHSLLYEKFTVYNELTKVKYKTEQGKTAFFDANMKQEIFDGVFKVYRKVTKDKLMDFLEKEFDEFRIVDLTGLDKENKVFNASYGTYHDLCKILDKDFLDNSKNEKILEDIVLTLTLFEDREMIRKRLENYSDLLTKEQVKKLERRHYTGWGRLSAELIHGIRNKESRKTILDYLIDDGNSNRNFMQLINDDALSFKEEIAKAQVIGETDNLNQVVSDIAGSPAIKKGILQSLKIVDELVKIMGHQPENIVVEMARENQFTKQGRRNSQQRLKGLTDSIKEFGSQILKEHPVENSQLQNDRLFLYYLQNGRDMYTGEELDIDYLSQYDIDHIIPQAFIKDNSIDNRVLTSSKENRGKSDDVPSKDVVRKMKSYWSKLLSAKLITQRKFDNLTKAERGGLTDDDKAGFIKRQLVETRQITKHVARILDERFYTETDENNKKIRQVKIVTLKSNLVSNFRKEFELYKVREINDYHHAHDAYLNAVIGKALLGVYPQLEPEFVYGDYPHFHGHKENKATAKKFFYSNIMNFFKKDDVRTDKNGEIIWKKDEHISNIKKVLSYPQVNIVKKVEEQTGGFSKESILPKGNSDKLIPRKTKKFYWDTKKYGGFDSPIVAYSILVIADIEKGKSKKLKTVKALVGVTIMEKMTFERDPVAFLERKGYRNVQEENIIKLPKYSLFKLENGRKRLLASARELQKGNEIVLPNHLGTLLYHAKNIHKVDEPKHLDYVDKHKDEFKELLDVVSNFSKKYTLAEGNLEKIKELYAQNNGEDLKELASSFINLLTFTAIGAPATFKFFDKNIDRKRYTSTTEILNATLIHQSITGLYETRIDLSKLGGD
>NZ_LS483349.1|WP_002280229.1|733889_734756_+|NADPH-dependent-oxidoreductase
MKLVAIVGSNASFSYNRLLLQFIKERFGQAFALEILEIKELPLFNQDSSAADCPLIQKLNEDILNADGIIIATAEHNQTITASLKSMLEWLSYQLHPFKNKPVMIVGASYYNQGTSHAQEHLRQILNAPGLDAWVMPGNEFFLGNASEVFDENNQIKDDDTVIYLAQCLQRFIRYVTVVQELKGDSIQLSDAISGASESVQEDSATSAMLEKQLSLQKKETNTPFERALDKTYGPALKDTLEDPFDKDLDAQYKAIKKQPIPFEKALDNIFGKDLGIETTDPLDNLLR
>NZ_LS483349.1|WP_002280228.1|732903_733770_+|helix-turn-helix-transcriptional-regulator
MVRFISNTLSQTLNEPFQQSHKSCKHLYILEILSQVVIVSDQKQVPLQPYDIILAQSFNHLQIDSLDRNPILLRLYSLDFDLPSPLNQYTVGDNPLIHDLMNDHTSEDAYILFTNLSDLICHAYLDALEKLENLRDNNDEQVYIDFQRQKLAGLLFTELLRQHDAKVSKFASRFPSVNVKYASKDSQSGAIMKYVSDNVHHISLKEAAAHFFYQANYFSRLCHELFGISFNQLKTTIRLEIAKEQLRLTTKSVEEISQELGYKAVSNFHRNFKSQTGMTPNDYRQDKQ
>NZ_LS483349.1|WP_002280227.1|731288_732779_-|FAD-dependent-oxidoreductase
MEKEYKVDVVVAGAGGAGLAAAHAAAQNGLKVLVLEKLKQIGGNTRISSGFFAINTKEQNAAGLKLSTQEAIRQLQEHNHFLSNGALLKNIIEHAKETLEEIEKLGMEIKLNPTKNSTQFAHFGNDYQGGSYHMYMNKDSSYLQIQKSLEAMGVTFIFGVRMTELLQDSNGHVRGLKALNDAGESMTVHAKASIITTGGFGGDKRRVAKVMRTLNLRTLGVPNMGEGLSAMEAAGGVNIDGSALIHAAQMAQSTVTQETKGKQLAGFNDSPLTQLLLSPLLWVDPNGSRFTNEDVVYDTVQWSNAAYGVGSKYYYVMDTATLESYTKQPLLTISKSGPGASQAKGDFVSLAEQAVQQGIAFKGDSLEELAQNSGMDPIAFKATVAEYNKAIASQNDEIFSKSASSLKYDVKKGPFYAFIAQVVYLGTVGGVRVDKDLRVLDAYMKAISGLYTGGANAGGYYAPRNYPAYEGLASGFSWTSGRLAGLAAANDIKKYN
>NZ_LS483349.1|WP_002279852.1|730103_731279_-|MFS-transporter
MNQKNLSPSSWFFKISVLSLSILAMTAPSISIANNLLQKTFTQQSTAEIEMISTLPNFGVLLLILFADTIANKFGIKRTIMAGLLMYLLGGVLPSFIPNYYAIVFLRFLMGCGIGLFNPFSVSLMYRFYKDQELSDMLGFQNTGQNLGNAGFGFLLGALVLAGWKVAFMGYFIALIPLILFGAFVVIPDDQPTIKKERPKLADSINGHILLLALLFLIIFGMFMMMTIKMALFGAETGLISASAASSILAVLGLSSMFSAIAFGKLSKRVGNFMLPISLTGIAMGFFIVASASNAAMVVLGVIIAGIFFGWVFPQAFLRAAQVGPKEGGTLTTSVILMGINLGAFLSPSVVNFVANLLGNKTAASVLAMCGWGFALLAILEYLYTFFNQRT
>NZ_LS483349.1|WP_002272311.1|742185_743079_-|LexA-family-transcriptional-regulator
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFASKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTIIHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKTKAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT
>NZ_LS483349.1|WP_002262720.1|743394_743679_+|helix-turn-helix-transcriptional-regulator
MQFVWESNGKLKGDAEVEKLTLRALRVNYSLSPKEVADCLGIPQHTLLSYEEDSSEIPIQLANDLANYYDISLDSIFFGKNSDLKQKFKNKNNR
>NZ_LS483349.1|WP_002279994.1|743841_745593_+|LPXTG-cell-wall-anchor-domain-containing-protein
MKSKTAKITLLSSLALAAFGATNVFADEASTQLNSDTVAAPTADTQASEPAATEKEQSPVVAVVESHTQGNTTTTTSQVTSKELEDAKANANQEGLEVTETEAQKQPSVEAADADNKAQAQTINTAVADYQKAKAEFPQKQEQYNKDFEKYQSDVKEYEAQKAAYEQYKKEVAQGLASGRVEKAQGLVFINEPEAKLSIEGVNQYLTKEARQKHATEDILQQYNTDNYTASDFTQANPYDPKEDTWFKMKVGDQISVTYDNIVNSKYNDKKISKVKINYTLNSSTNNEGSALVNLFHDPTKTIFIGAQTSNAGRNDKISVTMQIIFYDENGNEIDLSGNNAIMSLSSLNHWTTKYGDHVEKVNLGDNEFVKIPGSSVDLHGNEIYSAKDNQYKANGATFNGDGADGWDAVNADGTPRAATAYYGAGAMTYKGEPFTFTVGGNDQNLPTTIWFATNSAVAVPKDPGAKPTPPEKPELKKLTVTWHKNLVVETKTEEVPPVTPPTTPDEPTPEKPKTPEDPQSPVVAKSVSFRTARKGEMRVRERDYQPTLPHTGAAKQNGLATLGVISTAFAAATLIAARKKEN
>NZ_LS483349.1|WP_018110186.1|745722_745953_+|hypothetical-protein
MLIPSQFCGGGTAELKSQFHYDLPIFIPLFVVFVMGKFTISIMEILSSPKRSYDFIVRLNGLSLFDMQNIGIFNNN
>NZ_LS483349.1|WP_002262717.1|746364_748200_+|elongation-factor-4
MTIEQLKNRQEKIRNFSIIAHIDHGKSTLADRILEQTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPKGDVEAPLKALIFDSVYDAYRGVILQIRVMDGMVKPGDKIELMSNGKTFDVTEVGIFTPKAVNRDFLATGDVGYLAASIKTVADTRVGDTVTLADCPAEAPLHGYKQLNPMVFAGIYPIDSSKYNDMREALEKLQLNDASLHFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVYTTDGERLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEYVGAVMELSQRKRGDFVTMDYIDNNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDISEYRKSKLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDDDDKKK
>NZ_LS483349.1|WP_002279995.1|748228_749056_+|alpha/beta-hydrolase
MAALNKEMVNTLLGPIYTCHREGNPCLVFLSGAGFFSTADNFANIIDKLPDSIGILTIDAPNSGYSPVSNQVNVGLRDWVNAILMIFEHFKFQSYLLCVHSIGGFAALQIMNQSSKACLGFIGLEPTTAMIYRAGFSSDLYPQLALRRQKLKTAADRLNYLKDLSRSHFSSQQFKQLWRGYDYCQRRLNDVQSLPDFKIRLALGEEDFKTVISEKVPSIVFSESFREKEYLESEYLNKHTQTKLILCGQHHYLHWSETNSILEKAEQLLSNHEKL
>NZ_LS483349.1|WP_002268969.1|749134_749611_+|GNAT-family-N-acetyltransferase
MSIRLAQVTDIPVLKELLNQIFQVHQTVRPDLFKNTDKGSKYSETELKELLQDESKPIFVYTDGKNRVLGHLFLVIKETEGSSVSKPLKTLFIDDLCVSKEARGQKIGQELFEFALKYAKKLGCYDLTLNVWNDNKGALAFYERQGLKARETKMEKIL
>NZ_LS483349.1|WP_002270553.1|749690_750299_+|hypothetical-protein
MPRRRASRRKSKKKAVFSILLTGITLIIIGLAVYFISAYFTNTKKTANKEKTQTHIVNPKKDPEEKKEADSSSKATSKFDLTTIATGDYSSAAGTWQNELGDQLKFNASGLESATIQNATDFTISSGQATNDGLYQATLTSADSTVVYNLLFVKGGTAIPENYFTTGYSDTSDTSRDRLYISSQTTFGSDDFSKGIFYKSEN
>NZ_LS483349.1|WP_002269623.1|750363_751020_-|Pr6Pr-family-membrane-protein
MSKTQAFRSLIALLGLIGVSIQIKQSGWGMLLYYTTLSNVIVFSFLTYLVIKEKRNGSINSNPKLLRLKGGVTMTIMITFMVYHFLLAPKVRSYDYYTIRNFLVHYIVPLSTIFDTLICDRRKIYRWFDPIIWTCLPLLYFGFALINGLLLKWPIPGTADSPFPYFFINMNKYGAQQVLINALVIALLYLLFGYILLGIKQMIGQKRQVTDNSSLNMS
>NZ_LS483349.1|WP_002264337.1|751338_752979_+|phosphoenolpyruvate-carboxykinase-(ATP)
MVTRQHFSEDSMRKNNSYFSALKATIETAFYENHVVPLKELAEAYRLAAKSPNTIVLDTPVAHAEDLGLPKDAKILLENSGGIVGRTAKARRIFGQDSKEDAKILQIIREAIFQARHRTFYRADAVVGLDEAFMLRAHLMVPQDDINNLYSWLNNFQVLNDTYRERLKKSKRYEETDIYIFSDPEWSHPDYPDGLVYFDTNHNCAAILGLHYFGELKKATLTLAWGTANRNKYVACHGGLKIFEKEGQKPYVASFFGLSGSGKSTLTHAKHNGKYRIDVLHDDAFVISEEDGSTIALEPAYFDKTNDYPAGHREQKYFVAVQNCGAALDKEGHLRLVTEDIRNGNGRTIKSRFSTPNRVDRINHPIQSIFWIMKDDSLPPLIRVTDPIMASIMGCTLVTTRSTAENTTDSLDALIIEPYANPFRVYPLVEDYIKFQHLFESGVNCYIINTGSYLGQDIPKETTLDVIEQVVDGTAKFESFGSVKGFEYLSSSHYKIPNFDKAYVKIIRQRMKIRLQYLEAFNRKNPKLSLPDEAISHLKDVLANLG

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483349_2	2.4|741972|30|NZ_LS483349|CRT	741972-742001	30	DQ386162	Streptococcus phage M102AD, complete genome	17809-17838	0	1.0
NZ_LS483349_1	1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412306-412340	35	MT430910	Streptococcus phage smHBZ8, complete genome	16128-16162	1	0.971
NZ_LS483349_2	2.2|741971|31|NZ_LS483349|CRISPRCasFinder	741971-742001	31	DQ386162	Streptococcus phage M102AD, complete genome	17809-17839	1	0.968
NZ_LS483349_1	1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412306-412340	35	AM749121	Streptococcus phage M102 complete genome	15930-15964	2	0.943
NZ_LS483349_1	1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412306-412340	35	NC_012884	Streptococcus phage M102, complete genome	15930-15964	2	0.943
NZ_LS483349_1	1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412306-412340	35	DQ386162	Streptococcus phage M102AD, complete genome	16052-16086	2	0.943
NZ_LS483349_1	1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412174-412208	35	KJ608188	Enterococcus phage EFC-1, complete genome	9693-9727	4	0.886
NZ_LS483349_1	1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412174-412208	35	MK448822	Streptococcus phage Javan629, complete genome	8243-8277	7	0.8
NZ_LS483349_1	1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412174-412208	35	MK448930	Streptococcus phage Javan406, complete genome	9950-9984	7	0.8
NZ_LS483349_2	2.3|741906|30|NZ_LS483349|CRT	741906-741935	30	MT773554	Myoviridae sp. isolate BML_2 genomic sequence	115852-115881	7	0.767
NZ_LS483349_2	2.1|741905|31|NZ_LS483349|CRISPRCasFinder	741905-741935	31	MT773554	Myoviridae sp. isolate BML_2 genomic sequence	115852-115882	8	0.742
NZ_LS483349_1	1.6|412438|33|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT	412438-412470	33	NZ_CP028348	Novosphingobium sp. THN1 plasmid pTHN, complete sequence	1031216-1031248	10	0.697

1. spacer 2.4|741972|30|NZ_LS483349|CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 0, identity: 1.0

ctgttaattcaaactcatgtaacacaggct	CRISPR spacer
ctgttaattcaaactcatgtaacacaggct	Protospacer
******************************

2. spacer 1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 1, identity: 0.971

agagctcgaaaagagcataactaacccaacaacaa	CRISPR spacer
agagctcgaaaagagcataactaatccaacaacaa	Protospacer
************************.**********

3. spacer 2.2|741971|31|NZ_LS483349|CRISPRCasFinder matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 1, identity: 0.968

cctgttaattcaaactcatgtaacacaggct	CRISPR spacer
tctgttaattcaaactcatgtaacacaggct	Protospacer
.******************************

4. spacer 1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 2, identity: 0.943

agagctcgaaaagagcataactaacccaacaacaa	CRISPR spacer
agagcttgaaaagagcataactaatccaacaacaa	Protospacer
******.*****************.**********

5. spacer 1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 2, identity: 0.943

agagctcgaaaagagcataactaacccaacaacaa	CRISPR spacer
agagcttgaaaagagcataactaatccaacaacaa	Protospacer
******.*****************.**********

6. spacer 1.4|412306|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to DQ386162 (Streptococcus phage M102AD, complete genome) position: , mismatch: 2, identity: 0.943

agagctcgaaaagagcataactaacccaacaacaa	CRISPR spacer
agagcttgaaaagagcataactaatccaacaacaa	Protospacer
******.*****************.**********

7. spacer 1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to KJ608188 (Enterococcus phage EFC-1, complete genome) position: , mismatch: 4, identity: 0.886

aatttgaaatgtctatccaatcagaagatttatca	CRISPR spacer
aatttgaaatgtctatccaagcggaagatttaact	Protospacer
******************** *.********* * 

8. spacer 1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to MK448822 (Streptococcus phage Javan629, complete genome) position: , mismatch: 7, identity: 0.8

aatttgaaatgtctatccaatcagaagatttatca	CRISPR spacer
aatttgaaatgtctatccaagcagaagaccttgtt	Protospacer
******************** *******..*  . 

9. spacer 1.2|412174|35|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to MK448930 (Streptococcus phage Javan406, complete genome) position: , mismatch: 7, identity: 0.8

aatttgaaatgtctatccaatcagaagatttatca	CRISPR spacer
aatttgaaatgtctattcaagcagaagacctagtt	Protospacer
****************.*** *******..** . 

10. spacer 2.3|741906|30|NZ_LS483349|CRT matches to MT773554 (Myoviridae sp. isolate BML_2 genomic sequence) position: , mismatch: 7, identity: 0.767

gaaaagccagctcaagacgataatcttgag	CRISPR spacer
atacatccagctaaaggcgataatcttgaa	Protospacer
. * * ****** ***.************.

11. spacer 2.1|741905|31|NZ_LS483349|CRISPRCasFinder matches to MT773554 (Myoviridae sp. isolate BML_2 genomic sequence) position: , mismatch: 8, identity: 0.742

cgaaaagccagctcaagacgataatcttgag	CRISPR spacer
aatacatccagctaaaggcgataatcttgaa	Protospacer
 . * * ****** ***.************.

12. spacer 1.6|412438|33|NZ_LS483349|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028348 (Novosphingobium sp. THN1 plasmid pTHN, complete sequence) position: , mismatch: 10, identity: 0.697

aagatggctggaatatgaaggagaggtagaaag	CRISPR spacer
ttgatggctggaagatcaaggagagggcttcgg	Protospacer
  *********** ** *********     .*

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	491322 : 505165	18	Streptococcus_phage(84.62%)	NA	NA
DBSCAN-SWA_2	1031960 : 1040744	7	Bacillus_phage(50.0%)	NA	NA
DBSCAN-SWA_3	1175839 : 1182689	7	Bacillus_phage(50.0%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NZ_LS483349|491322:505165|DBSCAN-SWA
AATGGCACTTCTTGATGTAAAAAATTTAACAAAAAATTTCGGTGGTCTGACAGCTGTTGGGGATGTTACTCTGGAGCTTAATGAGGGAGAATTGGTCGGTCTGATTGGTCCTAATGGGGCAGGTAAGACTACACTTTTTAATTTATTGACTGGTGTCTATGAACCAAGTGAAGGAAGTGTGGAACTTGACGGTACTCTTTTAAATGGGAAGACACCTTATAAGATTGCTTCTTTAGGACTATCTCGTACTTTCCAAAATATTCGCCTCTTTAAGAATATGACCGTTATCGAAAATGTTTTAGTCGGTATGGAAAATACGCGCAATCCTCATCTCTTTTCGAGTTTTCTGCGCTTACCAAGTTTTTATTCAAATGAAACGGACTTACAGGAAAAAGCCATTGAACTTCTAAAAATTTTCAACTTAGATGACAAGGCTGATACTTTAGCGAAAAATCTTCCTTATGGACAGCAGCGGCGCTTGGAAATTGTGCGTGCACTGGCTACTAAGCCCAAAATCCTCTTTTTAGATGAACCAGCTGCGGGGATGAACCCTCAAGAAACGGCTGAATTAACTGAATTAATTCGTCAAATCAAAGAAGAGTTTAGTATTACTATTATGTTAATTGAACACGACATGAGTCTGGTTATGGATGTTACTGAACGTATTTATGTTTTGGAATACGGACGTCTCATTGCTCAGGGAACACCAGAAGAAATTAAGCACAACAAACGCGTAATTGAAGCTTATCTAGGAGGTGAAGCCTGATGGCGATGTTAAAAGTTGAGAATTTATCTGTTCATTATGGTGTTATTCAAGCAGTCAAAGATGTGTCTTTTGACGTCAATGAAGGGGAAGTCGTTTCTCTTATTGGTGCCAATGGTGCTGGCAAGACCTCTATTTTACGAACTATTTCGGGTTTGGTGCGTCCAAGTTCAGGGGAAATTAATTTTTTAGGAAATGATATTCAAAAAGCTGCAACTCGAAAAATTGTAGCTTCTGGTCTGTCTCAGGTTCCAGAAGGGCGACATGTTTTTCCTGGTTTAACAGTTTTAGAAAACTTAGAAATGGGAGCTTTTTTGAGCAATAATCGTGAGGAAAATCTAGCACGCTTAAAAAGAGTGTTTGAACGTTTCCCGCGCTTGGAAGAGCGTAAAAATCAAGATGCAGCAACCCTTTCTGGCGGTGAGCAGCAAATGCTTGCCATGGGGCGTGCTCTCATGAGTCAGCCTAAGCTGCTTTTGCTTGATGAGCCATCTATGGGATTGGCACCAATTTTTATACAAGAAATTTTTGACATCATTCAAGATATTCAAAAGCAGGGGACAACAGTGCTTTTGATTGAGCAAAATGCTAAGAAGGCCCTGTCAATTGCAGATCGTGGCTATGTTTTGGAAACTGGAAAGATTGTTCTTTCAGGTACAGGCAAAGAATTATTGGCTTCTGATGAAGTTCAAAAAGCTTATTTAGGTGGATAAAAAGAAAGAGTGGCAGAATAAGAATTGGCACATTCGTTTTTTGCTACTTTTTTATCAATTAAAGTGTTAATGACTTGAATATGCTATAATGAAAGAAAAAGAGTGAGGTTTTATTATGCCAGTAAAGGATTTTATGACAAGGAGAGTTGTTTATATTTCTCCAGATACAACTGTAGCCAAGGCGACAGATATCATGCGTGAGAAAAATTTGCGCCGTCTTCCGGTTATTGAAAATGATGTTTTAGTTGGTTTGCTGACTGAGGGAACTATCGCTGATGCTAATCCATCTAAAGCAACAAGTCTTTCTATTTATGAAATGAACTATCTTTTAAATAAGACCAAAGCCCGCGATGTTATGATTAAAGATGTTATTACGGTTTCAAAAGATGCTCGTTTAGAAGATGCGATTTATATTATGATGAAGCATAAAATTGGTGTCTTGCCTGTTGTTGATGGCAATCAGATGTCAGGTATCATCACTGATAAAGATGTTTTTCGTGCCTTTTTGGAAGTTTCTGGTTATGGTAAAGAGGGGATCCGGATAAGACTTTTAGCTGACGATAAAGTTGGTATTTTAGAACAGATTGTAAAAGATATTTCTGATGAAAAGCTCAATATTAAGCGGATTGTTGTTGCTGGACGTCGGGAAGATAAGGTTATCATTGAGATTCAGATTGATGGTAGATTTACCAGTGAATCTCTAAAACAAAAACTGCTTAATCAAGGCTTTACAATTGAGTCTATTGAACAGACTGAAAGAAAGACTGATTTTTAATTGGTTCTGCCATTTGGCAGTGCCTTTTTTTCATATTTTTGGTAAAATAGAATAATCATAATAAAAGGAAATCTAATGACAAAGGGAATTTTTATTTCATTTGAAGGACCAGATGGAGCCGGAAAGACGACAGTTTTAGAGGCTATTTTACCTCAATTAAAAAAACTTGTTGCAAAAGAGGTTATCACAACACGCGAACCCGGTGGTGTTGCTATTGCAGAAAGTATTCGGGATCTTATTCTTGATGTTAATCATACTAATATGGACGATAAGACAGAATTACTTCTTTATATTGCGGCTCGTCGTCAGCATTTGGTTGAGAGGATTTTACCTGAGTTGAAAAAAGGCAATCTTGTTCTTGTGGATCGTTTTATTGACAGTTCTGTTGCTTATCAAGGCTATGGCAGAGGACTTGATGCTGATGCAGTTACGTGGCTGAATAACTTTGCAACAGATGGTTTGCAACCAGATCTAACACTTTATTTTGACGTTGATTCACAGATTGGTCTTACTCGAATCGAGAAGAATAAAGAGCGTGAAGTCAATCGACTTGATTTAGAACAATTAGATATGCATTGCCGTGTACGTTCAGGTTATTTGAAATTGGCTCAGGAAAATCCTGATCGGATTGTTACCATTGATGCGGCTCGTCCTTTGGAAGAAGTTATTACTGATGCCTTATTTATAATCAAACAAAGATGTTTAGAAAAGTAAGAAATAATTAATATGGAATTAGAAAAACTACAGCCTAAAATTTTTCAAGAATTTCAGCGAATTTTACAATCTGGCAAGCTGAGCCATGCTTATTTGTTTTCGGGGGATTTTGCTAGTTTTGAAATGGCTGTTTTGTTGGCTCAGAGCCGTTTTTGTGACAGTCCTATTGATGCTCTTCCTTGTGGGCAGTGCCGTTCCTGCCGGTTAATTGCTGAAAAAGATTTTTCGGATGTTAAAGTCATTGAACCTGAAGGGCAAATGATTAAAACAGCAACGATCCGTGATTTGCTGCGTGAATTTTCCAGTTCAGGATTTGAAGGACAGTCACAGGTTTTTATTATTCGTGATGCTGATAAAATGCATACTAATGCCGCTAATAGCTTGCTAAAGTTTATTGAAGAGCCACAAAGTGATACTTATATGATTTTATTAACTCAAGATGAAAGTAGGATATTGCCTACGATTAAAAGTCGAACTCAAATTTTCTATTTTCCTAAGAATAGGGCTTATTTAATCCAACAGTTAGAACAGGAAGGACTACTCAAAAGCCAAGCAGAAATACTAGCGGATCTATCTAAAGATCCGACACAAGCAAAAGAATTTGCACAAAATAATAAATTGCTGGACTTGTTAAAAGCCTGTGAACGTTTTACCGCTATCTTATTTGACAGTAAAAATCTTGCTTATTTAGAAGTGTCACGGTTGGCTCAGCTAGCTAGCGAAAAATCCGAACAGGAATGGGTCTTTCAATTGTTAACTTTCTTTTTATCAAAAAATTATGATAAAAGGGAAACTTTAAGTTACTTAGAAGCTATTTATCAAGCCAAAAAAATGTGGTTTAGTAATGTAAGTTTTCAAAATGCACTGGAATATATGGTGATAACATGATAGAAGTAATTGGTATCAAATACGAAGAAACGGATAGCATTAGTTATGTACTGCCTGATCGGACCTATCAAAAGGATGATTTCCTTGTCGTTCAGAATCGTAAGGGAAGCCGTTTAGCACAAGTTGTTCAGGAAAATTTTGCTATGTCAGCCGACAAGCTTCCAGACATAGAGCAAATAGATAAAGTTTTGAGAAAGGCAGAGCAAGCAGATATTGAGACTTATCAGAACAATTTAATTTTAGCAGAAGAAAGTTTTGCTAAAGTTAATGCACTTATCCAAAAAAATCAATTAGAAATGAAATTGATTGATATTGTTTTTCCTTTGGAACGTCGGCAAGTCTTGATTACCTTTGTTGCAGAGCATCGTGTTGATTTTCGTCAGCTCTTAAAAGATTTGGCCAATTTTTTTAAAGCAAGGATTGAATTACACCAAATCAATAGTCGTGAAGAAAGTAAAATTTATGGCGGTCTGGGTCCGTGCGGCCGTGCTCTTTGTTGCTCAAGCTTTCTTGGCGAGTTTCCGCCGGTTTCTATCAAAATGGCAAAGAATCAAAACTTATCTCTGAATTCTGGGAAAACAACAGGAGTCTGTGGCCGTCTTATGTGCTGTTTAAGTTTTGAAGATGATTTTTATCGTGAATCCAAAGAAAAATTTCCTGATTTAGGTACTAAGGTCAATACTCAAAATGGCCAAGGTATTATTGCTGGTATTGATGTTATTTCTGAAACTGTTAAGGTTCGTTTTGAAGAAACTCCTGGTCTTTTGACCTATGCATTAGAGGAGGTCAAGATCAATGGATAAAAAAGACTTATTTGATGTTTTTGATGATTTTTCACAAAATTTGATGGAAACGTTGGCTGAAGCGGAAGCCTTAAAGAAACAAGTGCAGGATTTAGTAGAGCAAAATGCGTCTTTACGTTTGGAAAATGATAAGCTAAGAGACCGTCTTAGCCATTTTAGCCAGATGGAAGAAAGTGATCCTAGCAGTAAGGCAATTAGTTCTAGAAAAGAAAACCTTGAAAACATTTATGAAGATGGTTTCCATATTTGCACTTTCTTTTATGGGCAAAGACGAGAAAATAATGAGGATTGTGCTTTCTGTATGGAATTGTTGTATCGAGAGTAGGTCTTATGCAAGTACAAAAAAGTTTTAAAGAACAAACAGCTTATGGGAAGCTTTATCTCGTGCCAACTCCTATTGGTAATCTTCAAGATATGACTTTTAGAAGTATTGCTATTTTAAAAAAGGTTGATTATATTGCGGCAGAAGATACCCGCAACACAGGACTCTTGCTGAAACACTTTGATATTTCAACACGTCAGCTTAGTTTTCATGAGCATAATGCTTTTGAAAAAATTCCTGATCTTCTGAAGCTCTTGAAATCTGGAAACTCTTTAGCTCAAGTATCTGATGCGGGTTTGCCAAGTATTTCTGACCCTGGATATGATTTGGTGCGAGCAGCTATTCAAGAAGATATAGCAGTTATAGCACTTCCGGGAGCTTCGGCTGGCATTACTGCTCTTATTGCTAGCGGTTTGGCTCCTCAACCTCATATTTTTTATGGTTTTTTACCACGCAAATCTGGTCAACAAAAGTCTTTTTTTGAGGAAAAAAAGTATTACCCAGAAACTCAAATTTTTTATGAATCGCCTTATCGGGTTCAGGAAACTTTAGAAAATATGCTGGCTGTCTATGGTGATAGACAGATAGTATTGACCAGAGAATTGACCAAACTTTATGAGGAATATCAAAGAGGAAATATTTCAGAAATCTTAACTTATATTGCAGAAAATCCTCTTAAGGGAGAATGCCTCTTACTGGTATCTGGCTATGATCATCAAGAAAAAGAGCAGCAGGTAAGTGAAGTTGAACTGAAACATTTGGTTGAAGCTTTAGTTAAAGAAGGTATGAAACCTAATCAAGCTATCAAAAAAGTAGCTAAAGAGAATGATTTCAATCGTCAAGAACTATATCAACTCTATCATGAATTACAGTAGACAGTTTCGACTGTCTTTTTTCTTTGAGTATTAGTTCGTCTCGCTCTATGATCTTCGTAATTCATAAACTATCGATTGATAAGAGTCATGATTAGATAGAAATGTTAAAAAACATAATATATAACGAAAAAGATAAATGGTCACTGGAAATAGTTGAAATAAGCTTTAGAGCCCTAGTACTATAATATTTTCAAATAATATAAGATGTTATATTCTCTGAATTTTTAGAAAATTTCGCCAAAAAATCTTTTATTTTCCTGAAAATATGTTATATTATATAACATAAAGGGAGGTGCTGATAGATATGGATTCAGGATCTATAGCATTTATTATCATTTGTTCTGCGCTTGTTTTTTTAATGACACCGGGTTTAGCCTTTTTCTATGGAGGCTTGGGACGCCGCAAGAATGTCATCAATACAATGATGATGGCAGTTGTGCCACTTGCTTTGGCCTCGCTTTTGTGGGTAGTTGTAGGTTATTCCTTATCTTTTAGTGGTGTTGGAAAAGTATTTGGTGATTTTTCACATGTCTTTTTGAATGGTGTGAAGGAAGGAGCAAGTAGTAGAGGGTTAACAATACCAGATACCTTATTTTCTGGTTTTCAAATGATGTTTTCTATCATTACAGTAGCTATTTTGACAGGTGCTGTTGCAGGAAGGATGCGTTTCACTCCTTTAGTTATTTTTATTATCTTTTGGTTACTTTTAGTCTATTATCCTTTTGCACACATGGTTTGGGATGATGGTCTATTAGCGAAATGGGGGACGCTTGATTTTGCCGGTGGTGATGTTGTCCACATTACATCAGGCGTTTCGGGGCTGGTATTAGCCTTGGTAGTCGGTAAACGTCGCGATTATGACCGTCTGGATTATCGTCCACATAATATTCCCTTTGTTCTTTTGGGAGCAGGTCTACTCTGGTTTGGTTGGTTTGGGTTTAATGCAGGTTCCGCTTTAGCTGCTAATGGTTTGGCTGTTCATGCTTTGTTGACAACTCATATTTCAGCTGCCGCTGCTATGTTCTCATGGCTGCTACTTGAAAAATATTTAAATGGTAAACCTTCCTTAGTAGGCGGTTCAACTGGTTTAGTCGCAGGCTTAGTTGCCATTACATCAGGTGCAGGCTTTGTACCCTTATGGAGCTCTTTGTTGATAGGACTCATGGTTAGTCCTCTATGTTATTTTGCTATCGCTGTGTTGAAAAGTAAATTTGGTTATGATGATGCCTTGGATGCTTTTGGCTGTCATGGTATAGGTGGTATTTTCGGAGGGATTGTAACAGGACTTTTTACAACACCTCATCTGGCTTTAGATAAATCCAATATTGGTCTTATTTATGGTAATGCAAGATTATTTTTAGTTATTCTGGCAGCTATTCTTTTTACGATTATTTGGTCAGCTCTGATTAGTTTTTTAATTATAAAAGTTATTTCCCTTTTCATGCCAATTCGTGTCAGTGATAGAGAAGAAGCTACTGGACTTGACGACAAAGAGCATGGAGAAACTGCGTATCCAACCTTTATGGGACTTGATTCTTAGGAGAAAGGAAGTATCATGAAAAAAATAGAAGCTATTATTCGCTCTGATAAATTAGAAGATTTAAAAGCAGCCTTGGTTCAGTCAGGTTTTACCAAAGGAATGACTATTAGCCAAGTTCTAGGATTTGGGAATCAACGAGGTTATACAGAATATGTCCGTGGTCAAAAGATCACTCCAACGCTCTTAGCCAAAGTGAAAGTTGAAATTGTTGCTCATGATGCAGCAGTCGAAGAAATGATTACGACCATCAGCCAAGCAGTAAAGACAGGAGAAGTTGGTGATGGTAAGATATTTGTCAGTCCAGTTGATGAAATTGTTAGAATTCGTACAGGAGAACGTGATGGTGATGCCATTTAAGTTGCCTGTCTTTGCTATTAATATTGCTGCTCAAAGAAAGATTTAAGCTTTTTGATAAGTACGTCCTAAAGATAAGTTAAGCTTTTCGTTTTTAGGATGTGCTTTTTTTGAAAAACAAATTTTTGAGGTATGAATTTTAAAAATTTGTCTTTAAATGAAATTAGTTTACAAAATTCTGAAAATTTGTGATATAATTTACTTACTTTAAGGAGGTATCAGATGACAATTTATAATTTTTCTGCAGGTCCTGCAGTCTTGCCAAAACCAGTTCTTGAAAAAGCTCAGACTGAATTTCTAGATTACAATCATTCTGGCATGAGTGTTATGGAATTATCCCATCGTTCCAAAGATTTTGATGACATCATTAAAGATGCCGAAAAATTACTTCGTGACTTGATGGCTATTCCTGATAATTACAAGGTCATGTTCTTGCAAGGCGGAGCTTCGACACAATTTTCTATGTTACCACTTAATCTTGCACAGGGACGTAAAGCTTATTATGTGGTTGCAGGATCCTGGGGGAAAAAAGCATATGCAGAAGCTGTAAAATTGTCCAAAACGATTCCTTTTGAACCAATCCTTCTGGCTTCATCAGAAGAGACAACTTATGATCATATCCCAGAAATTGATTCTGCGAAGATTGATAAAGATGCTGCTTATGTGCATATTACGACTAATAATACCATTGAAGGAACTTCTATCTATGATCTTCCTGAAACGCATGGTGTGCCAATTGTAGCTGATATGTCTTCCAATATTTTAGCAGTTCGTTATAATGTCGCTGACTTTGGCTTGATTTATGCAGGAGCACAAAAGAATATTGGACCTGCTGGGGTTACGATTGTTATTGTTCGTGAAGATCTACTCAATGACGAGCCCGTTCTTTCTAGTATGTTAGATTATCGTATTCAAGCTGAAGCTGGTTCGCTTTATAATACACCACCAACTTACGGTATTTATATTGCTAAACTTGTCTTCGAATGGCTTAAAGAACTTGGTGGCGTTGATGAAATGGAAAAAATCAATCGTGAAAAATCAGGCCTTCTTTATGATTTCATTGAACAGTCAGATTTTTATACTAGTCCTGTCAAGAGTCCTAAAGATCGCTCAGTAGCCAATATCCCATTTGTGACACCATCTAAGGATTTGGATGCTAAATTTGTCAAGGAAGCTGATGCGCTTGGTTTCAAGAATATCAAAGGTCACCGAAGTGTTGGCGGTATGCGTGCCAGTCTTTACAATGCCTTTCCACGTCAAGGTGTTTTAGATTTGATTGACTTCATGAAGAAATTTGAAGCAGAAAACAAATAATATCGTAGAACTTCCGTAGGAATATTGCTGGTCAATCCCTTTAGGAGGACACCGTTGGTTATTCTCGTCTTGTCATTATTGGTGATTCGATTGAGGTCACCGGAACAATAGCTATTAATGATGAAAACCTTGTGCTGTTGGCATGCCTATGAACAAACGCGTTTCGTTTTGCAGTCTATTATGGATTTGTTTACTAAAGAGGAACTTCCTTTTGAAAATCTCTATCGGACACGTCTGTTTGTCACTGATATTTCATGATGGGAAGAAGTCGGACGTGCGTATGGTGAATTTTTCAAAGAGGTAAAATCTGTGGCTACTATGGTAGAGGTGCCTTCGTTGATTGACAAGGACTTACTAGTCGAAATTGAAGTTTTTGCTAAACTAGAAAAATAGGAGTAACAGATAAGAATGGAAATTAGACAAGCTTTCCCCAATGAAGTCGATGTCGTAATGGCAGTCCTCAGTTCTGCCAAGCAATTTTTAGCAGAATCAGGATCTAGTCAGTGGCAGGGTGAAAATGGTTACCCCAACGAAGACGATGTCTTTGATGACATTTTGCAGGGGCAGGCTTATGTGGCGGTTGTTGGTGGACAAATTGTGGCTTATGCTGCAGTCATTGATGGCAAAGATGAGGCTTATGACAAAATTTATGATGGCAAATGGCAGCACAACAACTATCGTTATGTCACCATCCATCGTCTAGCTGTCTTGCGAGATTTTGCGGGTCAAGGGATTGCTCAGACTTTCTTGCAGGGTCTGATTGAAGGTCAGGCTGGTTCAGATTTCCGTATTGATACGCATAAAAAGAACAAAGCTATGCGGCATATCGTTGAAAAATTAGGCTTTGTCTATTGCGGTAAAGTACCAATTGATGGTGAGCGTTTAGCTTATCAAAAAATCAAACAGAATAATGAGAATGCTCTCTATCAAGAAATTGATGAAGCAGATTATCATGGCTTTTAAATTTCAATTGTCAGCTGCTAGTAGAGCACTTAAATAGGGTAGAAAGAGAGACCTGAGCTAATCAGGTTCTATTGGTGAATGAAAAATGGTCTATAGTGTTAAAACCTTTAATAATATTAACCAAGTCGGTTTAAAAGAACTTGGCAATAAGTTTCAAGTAGATGGAGATTTAGCAGAAAATCCAGATGCTTATATTATTCGCAGTCAGAATTTACATGGGGCTGATTTTCCTAAAAATCTGAAAGCCATTGCACGCGCAGGTGCTGGAACAAATAATATTCCAATTACTGAAGCGACAGAAGCAGGTATTGTTGTTTTCAACACTCCTGGTGCTAATGCCAATGCTGTCAAAGAAGCAGTAATTGCTTCTCTTCTCTTTTCAGCGCGTGATTATATTTCAGCGAATGGCTGGGTTAATACTTTAACTGGTGATGATGTTCCTAAACAAGTTGAAGCTGGGAAAAAACAATTTGCAGGCAGTGAAATCGCTGGAAAAACCTTAGGAATTATTGGTCTAGGTGCGATTGGTGCTCGTATTGCTAATGATGCCCGCCGTTTAGGAATGAATGTTCTTGGTTATGATCCTTATGTTTCCATTGAAACTGCTTGGAATATCTCCAGTCATGTTAAGCGTGTCAATGATTTAAAAGATATTTTTGAGAATAGTGATTATATTACCATCCATGTTCCTTTAAATGATGAAACTAAAAATACCTTTAATGCTGATAGTTTTGCTCTTATGAATAAAGGGACAACTATTATCAATTTTGCCCGTGGTGAATTGGTTGACAATGAAGCGCTGTTTGAAGCGCTTGAAACAGGCACTGTTAAACGCTATATCACAGACTTTGGTACTGAAGAATTATTAAATAAGAAGGGGATTACTGTCTTTCCACACGTGGGAGGGTCAACTGAAGAAGCTGAACTCAACTGTGCTATTATGGCTGGTAAGACGATTCGTCGGTTTATAGAGACAGGAGAAATTACTAACTCTGTCAATTTTCCAAATATGCACCAAACTTTAACCGGACCTTATCGAATTACCTTAATTAATAAAAATGTTCCTAATATTGTAGCTCGTTTGTCAACTGCAGTTTCTAATTTAGATATCAATATCGCCAATATCTTGAACCGTTCAAAAGGAGATTATGCCTATACCATTTTGGATCTTGATGAAACAGATAAGGCAAAAATTGATGACCTAGTTGCTAATTTTGAAGCGAGTGACAATATTGTTCGTGTACGCTTAATCAGGGGCAAAAAATAAGATGATATATATACTAGGATTAGGGTGGTGAGCAGTTTTAACCATTGACTGTTTTTGCCCTTTTTATGGCTGAAAAGGAGGGAAAATGATGGTCCTTTACAAGCAGATTTATCATTCTCCTTTGGGAGATTTATCTCTTGTTGCAAATAATCAGGGTCTAATTGGCGTTTGGTTCCTTAATCAAAAATACTTTGAACAAGGATTGGAGGGAGAAACAGTCATAGAGCAAGCAAATACTATCTTAGATCAAGCCAAACAGTGGCTAGATACTTATTTTGCTGGGGAAAACCCTAATATGGTAAAGTTTCCTTTGAATCCACGGGGGACTGCTTTTCAAAAGCGCGTCTGGCAGGCCTTGTCTGAAATTCCTTGGGGACAGACTAGAGCTTATGGAGATATTGCTCAAAAAATAAACTGCCCATCCGCCCGAGCAATTGGTGGATCAGTTAGTCGCAATCCGTTAAGTATCATTATCCCTTGTCACCGTGTTCTTGGTGCTGCCGGTCAAATGACAGGCTATGCTGCTGGTATTGATAAAAAGATGTGGTTATTAGAGCATGAAGGCTTTAAAGTTGACAAGTAATTTATCTTTGCTAAGATAAATTTGAAAGGAGAACATATGCTGACATTTTACGAATATCCTAAATGCAGTACCTGTCGCCGTGCCAAAGCAGAATTAGACGATTTGGCTTGGGATTATGACGCAATTGATATCAAAAAGAATCCACCTGCAGCTAGTCTAATAAGGAATTGGCTAGAGAACAGCGGTCTAGAACTTAAGAAATTTTTCAACACATCAGGACAATCTTATCGTGCTCTGGGATTAAAAGATAAACTTCATCAACTAAGTCTTGATGAAGCAGCGAATTTATTAGCTAGCGATGGTATGCTCATCAAACGCCCGCTTTTAGTAAAAGAGGGTAAAATAGTACAAATAGGCTATCGAACAGCCTACAAAGATCTTGACTTTTAAAGTCGAGATTTTTTCTTTCCTTTCTTTTTCATGCTATAATGAGCTCAAGGAGAATTTGACAATTATGGTTTTATCAAAAAAACGTGCTCGTAAAGTATTAGAAGAAATTATTGCGCTTTATCCAGATGCTGTTCCTAGCTTAAATTTTAAAAATCATTTTGAGTTGTTAATTGCTGTTATTTTATCAGCTCAGACAACAGATGCAGCAGTTAATAAAGTGACTCCTGCCTTATTTGCAGCTTATCCGAGACCAAAAGATCTAGCTAAGGCTGACTTGAAAGATCTTGAATCTTATATTTCTCAGATTGGACTCTATCGGAATAAGGCGAAATTCTTAAAAGAATGTTCGCAACAGTTAGTCGAGCATTATAATGGTCAAGTACCTCAAACGAGAAAAGAACTAGAAAGCTTGTCTGGTGTCGGTCGCAAGACAGCTAATGTTGTCATGAGTGTCGGCTTTGGTCTTCCTGCCTTTGCGGTAGACACCCATGTCAGCCGTATTTGTAAGCATCACAATATTGTGAAACAAACAGCAACTCCTTTAGAAGTGGAAAAGCGTGTGACAGAAGTACTCCCGCCAGAAGAATGGCTGCCAGCCCACCAAGCACTCATTTATTTTGGGCGGGAAGTTTGCCATCCAAAAAATCCTGAATGTCAAAAGTATCCGCAATTGTATGAATTCGATTGAGCATTCGGTACCAATAAAAATAACCTCTGCAGTGAGTTAATTTTCACTTGCAGAGGACTTTTGTTTATAAATCAATTTTCAGCAGAATAGGGGTATGGTCTTGACGAGTTCCTGAATCAATCATTTCAGATTTAAGAATTTTATCGCTTAATCGATTGCTGATTAGCCAGTAGTCAATTCTCCAGCCTGAATTGTTAATCTTGCTGGTCTTGCTGCGCTGAGCCCACCAGCTGTAAACATTAGGCACATCCCCATGAATATAGCGGAAAGTGTCAGTAAAGCCTTGTTCCAATAAATGAGTAAAGCCAGCCCGTTCTTCATCTGTAAAGCCTGGTGAACGGCGATTGGAAGAAGGATGAGCGAGGTCAATTTCCTTGTGGGCAACATTATAGTCGCCTGTTGCCAGAACAGGTTTTTGCTTATCTAATTGAGCTAGATAAATGGCATACTTTTCATCCCAAATTTGACGATCATCAAGGCGTTTAAGGCCATCACCAGCATTTGGTGTATAAACCTGAGTAACAAAGAAATCATCAAATTCTAAGGTAATGATACGCCCTTCGTCATCCATGGTTGCAGGAGCGCCGATTTCTGGATAGGTGATAGTAGGTTGCAAGTTTGATTTGTAGAGAAACATGGTTCCAGCGTAACCTTTACGCGCAGGTTCCACTGAAGAACGCCAAACAACATCATAGTCGGGGAAATAATCCTTGAGAATACGCAAATGTTTTTTCGTGGGACCTTTGGCAGATAGCTTTGTCTCCTGAATAGCCAAGATATCGGCATCTTGTTCCATAAGTGTATCCAGAACAGCACGTGAAAGTAAAGCACGCGCAGAATCGCTGGTCAGGGCAGCGTTGAGGGAATCAATGTTCCATGAGATAAGTTTCAT

Protein sequences of DBSCAN-SWA_1

>NZ_LS483349|491322:505165|502700_503195_+|WP_002262692.1|DBSCAN-SWA
MVLYKQIYHSPLGDLSLVANNQGLIGVWFLNQKYFEQGLEGETVIEQANTILDQAKQWLDTYFAGENPNMVKFPLNPRGTAFQKRVWQALSEIPWGQTRAYGDIAQKINCPSARAIGGSVSRNPLSIIIPCHRVLGAAGQMTGYAAGIDKKMWLLEHEGFKVDK
>NZ_LS483349|491322:505165|495969_496302_+|WP_002271433.1|DBSCAN-SWA
MDKKDLFDVFDDFSQNLMETLAEAEALKKQVQDLVEQNASLRLENDKLRDRLSHFSQMEESDPSSKAISSRKENLENIYEDGFHICTFFYGQRRENNEDCAFCMELLYRE
>NZ_LS483349|491322:505165|497478_498714_+|WP_002280199.1|DBSCAN-SWA
MDSGSIAFIIICSALVFLMTPGLAFFYGGLGRRKNVINTMMMAVVPLALASLLWVVVGYSLSFSGVGKVFGDFSHVFLNGVKEGASSRGLTIPDTLFSGFQMMFSIITVAILTGAVAGRMRFTPLVIFIIFWLLLVYYPFAHMVWDDGLLAKWGTLDFAGGDVVHITSGVSGLVLALVVGKRRDYDRLDYRPHNIPFVLLGAGLLWFGWFGFNAGSALAANGLAVHALLTTHISAAAAMFSWLLLEKYLNGKPSLVGGSTGLVAGLVAITSGAGFVPLWSSLLIGLMVSPLCYFAIAVLKSKFGYDDALDAFGCHGIGGIFGGIVTGLFTTPHLALDKSNIGLIYGNARLFLVILAAILFTIIWSALISFLIIKVISLFMPIRVSDREEATGLDDKEHGETAYPTFMGLDS
>NZ_LS483349|491322:505165|500790_501345_+|WP_002280197.1|DBSCAN-SWA
MEIRQAFPNEVDVVMAVLSSAKQFLAESGSSQWQGENGYPNEDDVFDDILQGQAYVAVVGGQIVAYAAVIDGKDEAYDKIYDGKWQHNNYRYVTIHRLAVLRDFAGQGIAQTFLQGLIEGQAGSDFRIDTHKKNKAMRHIVEKLGFVYCGKVPIDGERLAYQKIKQNNENALYQEIDEADYHGF
>NZ_LS483349|491322:505165|499290_500382_+|WP_002280198.1|DBSCAN-SWA
MTIYNFSAGPAVLPKPVLEKAQTEFLDYNHSGMSVMELSHRSKDFDDIIKDAEKLLRDLMAIPDNYKVMFLQGGASTQFSMLPLNLAQGRKAYYVVAGSWGKKAYAEAVKLSKTIPFEPILLASSEETTYDHIPEIDSAKIDKDAAYVHITTNNTIEGTSIYDLPETHGVPIVADMSSNILAVRYNVADFGLIYAGAQKNIGPAGVTIVIVREDLLNDEPVLSSMLDYRIQAEAGSLYNTPPTYGIYIAKLVFEWLKELGGVDEMEKINREKSGLLYDFIEQSDFYTSPVKSPKDRSVANIPFVTPSKDLDAKFVKEADALGFKNIKGHRSVGGMRASLYNAFPRQGVLDLIDFMKKFEAENK
>NZ_LS483349|491322:505165|498729_499071_+|WP_002264023.1|DBSCAN-SWA
MKKIEAIIRSDKLEDLKAALVQSGFTKGMTISQVLGFGNQRGYTEYVRGQKITPTLLAKVKVEIVAHDAAVEEMITTISQAVKTGEVGDGKIFVSPVDEIVRIRTGERDGDAI
>NZ_LS483349|491322:505165|494298_495174_+|WP_002280200.1|DBSCAN-SWA
MELEKLQPKIFQEFQRILQSGKLSHAYLFSGDFASFEMAVLLAQSRFCDSPIDALPCGQCRSCRLIAEKDFSDVKVIEPEGQMIKTATIRDLLREFSSSGFEGQSQVFIIRDADKMHTNAANSLLKFIEEPQSDTYMILLTQDESRILPTIKSRTQIFYFPKNRAYLIQQLEQEGLLKSQAEILADLSKDPTQAKEFAQNNKLLDLLKACERFTAILFDSKNLAYLEVSRLAQLASEKSEQEWVFQLLTFFLSKNYDKRETLSYLEAIYQAKKMWFSNVSFQNALEYMVIT
>NZ_LS483349|491322:505165|500499_500640_+|WP_002270504.1|DBSCAN-SWA
MMKTLCCWHAYEQTRFVLQSIMDLFTKEELPFENLYRTRLFVTDIS
>NZ_LS483349|491322:505165|496307_497174_+|WP_002264025.1|DBSCAN-SWA
MQVQKSFKEQTAYGKLYLVPTPIGNLQDMTFRSIAILKKVDYIAAEDTRNTGLLLKHFDISTRQLSFHEHNAFEKIPDLLKLLKSGNSLAQVSDAGLPSISDPGYDLVRAAIQEDIAVIALPGASAGITALIASGLAPQPHIFYGFLPRKSGQQKSFFEEKKYYPETQIFYESPYRVQETLENMLAVYGDRQIVLTRELTKLYEEYQRGNISEILTYIAENPLKGECLLLVSGYDHQEKEQQVSEVELKHLVEALVKEGMKPNQAIKKVAKENDFNRQELYQLYHELQ
>NZ_LS483349|491322:505165|495170_495977_+|WP_002274530.1|DBSCAN-SWA
MIEVIGIKYEETDSISYVLPDRTYQKDDFLVVQNRKGSRLAQVVQENFAMSADKLPDIEQIDKVLRKAEQADIETYQNNLILAEESFAKVNALIQKNQLEMKLIDIVFPLERRQVLITFVAEHRVDFRQLLKDLANFFKARIELHQINSREESKIYGGLGPCGRALCCSSFLGEFPPVSIKMAKNQNLSLNSGKTTGVCGRLMCCLSFEDDFYRESKEKFPDLGTKVNTQNGQGIIAGIDVISETVKVRFEETPGLLTYALEEVKING
>NZ_LS483349|491322:505165|493647_494286_+|WP_002264028.1|DBSCAN-SWA
MTKGIFISFEGPDGAGKTTVLEAILPQLKKLVAKEVITTREPGGVAIAESIRDLILDVNHTNMDDKTELLLYIAARRQHLVERILPELKKGNLVLVDRFIDSSVAYQGYGRGLDADAVTWLNNFATDGLQPDLTLYFDVDSQIGLTRIEKNKEREVNRLDLEQLDMHCRVRSGYLKLAQENPDRIVTIDAARPLEEVITDALFIIKQRCLEK
>NZ_LS483349|491322:505165|504337_505165_-|WP_002266825.1|DBSCAN-SWA
MKLISWNIDSLNAALTSDSARALLSRAVLDTLMEQDADILAIQETKLSAKGPTKKHLRILKDYFPDYDVVWRSSVEPARKGYAGTMFLYKSNLQPTITYPEIGAPATMDDEGRIITLEFDDFFVTQVYTPNAGDGLKRLDDRQIWDEKYAIYLAQLDKQKPVLATGDYNVAHKEIDLAHPSSNRRSPGFTDEERAGFTHLLEQGFTDTFRYIHGDVPNVYSWWAQRSKTSKINNSGWRIDYWLISNRLSDKILKSEMIDSGTRQDHTPILLKIDL
>NZ_LS483349|491322:505165|492086_492797_+|WP_002262679.1|DBSCAN-SWA
MAMLKVENLSVHYGVIQAVKDVSFDVNEGEVVSLIGANGAGKTSILRTISGLVRPSSGEINFLGNDIQKAATRKIVASGLSQVPEGRHVFPGLTVLENLEMGAFLSNNREENLARLKRVFERFPRLEERKNQDAATLSGGEQQMLAMGRALMSQPKLLLLDEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNAKKALSIADRGYVLETGKIVLSGTGKELLASDEVQKAYLGG
>NZ_LS483349|491322:505165|503649_504273_+|WP_002264017.1|DBSCAN-SWA
MVLSKKRARKVLEEIIALYPDAVPSLNFKNHFELLIAVILSAQTTDAAVNKVTPALFAAYPRPKDLAKADLKDLESYISQIGLYRNKAKFLKECSQQLVEHYNGQVPQTRKELESLSGVGRKTANVVMSVGFGLPAFAVDTHVSRICKHHNIVKQTATPLEVEKRVTEVLPPEEWLPAHQALIYFGREVCHPKNPECQKYPQLYEFD
>NZ_LS483349|491322:505165|491322_492087_+|WP_002262678.1|DBSCAN-SWA
MALLDVKNLTKNFGGLTAVGDVTLELNEGELVGLIGPNGAGKTTLFNLLTGVYEPSEGSVELDGTLLNGKTPYKIASLGLSRTFQNIRLFKNMTVIENVLVGMENTRNPHLFSSFLRLPSFYSNETDLQEKAIELLKIFNLDDKADTLAKNLPYGQQRRLEIVRALATKPKILFLDEPAAGMNPQETAELTELIRQIKEEFSITIMLIEHDMSLVMDVTERIYVLEYGRLIAQGTPEEIKHNKRVIEAYLGGEA
>NZ_LS483349|491322:505165|503231_503585_+|WP_002272344.1|DBSCAN-SWA
MLTFYEYPKCSTCRRAKAELDDLAWDYDAIDIKKNPPAASLIRNWLENSGLELKKFFNTSGQSYRALGLKDKLHQLSLDEAANLLASDGMLIKRPLLVKEGKIVQIGYRTAYKDLDF
>NZ_LS483349|491322:505165|492912_493572_+|WP_002264029.1|DBSCAN-SWA
MPVKDFMTRRVVYISPDTTVAKATDIMREKNLRRLPVIENDVLVGLLTEGTIADANPSKATSLSIYEMNYLLNKTKARDVMIKDVITVSKDARLEDAIYIMMKHKIGVLPVVDGNQMSGIITDKDVFRAFLEVSGYGKEGIRIRLLADDKVGILEQIVKDISDEKLNIKRIVVAGRREDKVIIEIQIDGRFTSESLKQKLLNQGFTIESIEQTERKTDF
>NZ_LS483349|491322:505165|501430_502612_+|WP_002280196.1|DBSCAN-SWA
MVYSVKTFNNINQVGLKELGNKFQVDGDLAENPDAYIIRSQNLHGADFPKNLKAIARAGAGTNNIPITEATEAGIVVFNTPGANANAVKEAVIASLLFSARDYISANGWVNTLTGDDVPKQVEAGKKQFAGSEIAGKTLGIIGLGAIGARIANDARRLGMNVLGYDPYVSIETAWNISSHVKRVNDLKDIFENSDYITIHVPLNDETKNTFNADSFALMNKGTTIINFARGELVDNEALFEALETGTVKRYITDFGTEELLNKKGITVFPHVGGSTEEAELNCAIMAGKTIRRFIETGEITNSVNFPNMHQTLTGPYRITLINKNVPNIVARLSTAVSNLDINIANILNRSKGDYAYTILDLDETDKAKIDDLVANFEASDNIVRVRLIRGKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002262678.1|491322_492087_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-16	26.4
WP_002262679.1|492086_492797_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-19	28.9
WP_002264029.1|492912_493572_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.6e-67	60.6
WP_002264028.1|493647_494286_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.3e-75	65.1
WP_002280200.1|494298_495174_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.9e-78	53.8
WP_002274530.1|495170_495977_+	signal peptidase II	NA	NA	NA	NA
WP_002271433.1|495969_496302_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.1e-29	59.1
WP_002264025.1|496307_497174_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	73.9
WP_002280199.1|497478_498714_+	ammonium transporter	NA	NA	NA	NA
WP_002264023.1|498729_499071_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_002280198.1|499290_500382_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.4e-169	79.0
WP_002270504.1|500499_500640_+	hypothetical protein	NA	NA	NA	NA
WP_002280197.1|500790_501345_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	2.1e-50	63.3
WP_002280196.1|501430_502612_+	D-3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	3.0e-179	79.3
WP_002262692.1|502700_503195_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	9.7e-47	56.1
WP_002272344.1|503231_503585_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	2.1e-40	67.0
WP_002264017.1|503649_504273_+	endonuclease III	NA	NA	NA	NA
WP_002266825.1|504337_505165_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	7.4e-124	76.9

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NZ_LS483349|1031960:1040744|DBSCAN-SWA
GATGGATAAAATTGAAGAAGCACTTAGAGAGGGACAGGCAGTTGTTCTGCCAACAGAAACCGTCTATGGTCTTTTTGCTCAAGCTTTGAGCAAAAGAGCTGTTGATAATGTTTATGATTTAAAAAAACGGCCACGCGAAAAAGCAATGAACTTAAACGTTGCCTCTTTAGAAGATATTTTGGCTTTTTCAAAAGAGGCACCAGCTTATTTGGCAGAACTCTATAAAGCTTTTTTACCGGGTCCCTTAACCATTGTCTTGAAAGCTAACGAAAAAGTGCCAGCTTGGATTAATGGCGGTTTATCAACTGTTGGTTTCAGGGTCCCCGCCCACCCTCAAACTCTAGCCTATATCAAACAGACTGGTCCTTTAATTGGCACTTCAGCTAATTTATCTGGTCAAGCAAGTGGTTTGGTTTATCGGGAAATTCAAGAGGCTTTTGCTAATCGTTTATTAGGTATTCAGGATGATAAGGCAATAAAAGGAAGAGACTCGACTATTTTAGATATTTCAAGTTCCCGAGCAAAGATTCTGAGACAAGGAGCGCTTACACAGGACGCTATTCAAGCGCATGTGAAAGATATAAGATTTTAAGGAGAAAAAATGATTTTTGATAAAGATAATTATGAAGAGTACGATAGAGAAGTCTGGGAAGCTATTCACGCAGAAGAAAAGCGACAGCAAAACAATATTGAATTAATTGCCTCTGAAAATGTGGTTTCTAAAGCAGTCATGAAGGCGCAGGGGTCTATTTTGACTAATAAATATGCTGAAGGTTATCCTGGCCGTCGTTATTATGGCGGTACAGACTATGTTGATGTAGTTGAGAGTTTGGCTATCGAACGTGCTAAAAGACTTTTTGGTGCTAAATATGCTAATGTTCAACCCCACTCTGGTAGTCAAGCGAATGCTGCAGCTTATATGGCACTTATCAAGCCCGGTAATACTGTTATGGGCTTAGATTTGGCTGCTGGTGGTCATTTGACACATGGCTCCCCAGTTAGTTTTTCTGGGCAAACCTATAACTTCATAGCTTACAATGTTGATCCTGAAACAGAAGTTTTGAATTATGAACAAATTTTAAAACAGGCTGAAGAAGTGCAGCCTAAGTTAATTGTTGCTGGGGCATCTGCTTATTCTCATATCATTGATTTTAAAAAATTCCGTGACATTGCAGACCAAGTTGGTGCAAAACTTATGGTTGACATGGCCCACATTGCTGGCTTGGTTGCTGCCGACTTGCATCCAAATCCTGTACCTTATGCTCATATTACAACAACAACGACTCATAAAACTCTTCGTGGCCCTCGCGGTGGGCTCGTCTTGACCAATGATGAAGATTTAGCTAAAAAAATCAATTCTGCTATCTTCCCTGGTTTGCAAGGTGGTCCTTTGGAACATATTGTTGCGGCCAAGGCTATCACTTTCAAGGAAAATTTAGATCCTGCTTTTAAAGTTTATGCGCAAAAAATTATTGAAAATTGCCAAGCAATGGTAGAAGTTTTCAATGCTCACGAAAAATTCCGTGTTGTTTCTGGTGCTAGTGAAAACCATCTTTTCCTCGTTGATGTCACACAAGTTGTTGAAAACGGTAAAGTGGCTCAGAATATTTTAGATGATGTTCATATCACATTGAATAAAAATTCTATTCCTTTTGAAAAGCTGTCACCGTTTAAAACTTCAGGTATTCGCATTGGAACGGCAGCAGTAACAGCGCGTGGTTTTGGTCCTGAAGAATGCCGTAAAGTGGCTGAATTGATTGTTAAAACCCTTGAAAATACCGAAAATGAAGCAGTGTTAGAAGAAGTGCGTCAAGAAGTTAAACTTTTGACAGATGCTTTCCCACTTTATGAGAATCTTGTATGATGGATTTGTATTTAAAAAAGATTGTCATTCACCAATTTACTCCAGATGATACTGAGCTCATTCTTTCGGATAAATGCTTAACTATTACACCCAATTTAGATACTTATTTTCGAAAAAAAGTAGGTAAAGTTTTTTCTGACGAAGCTAGGCGTGGTCAGTTTGATAGTGGTAATGTCTTTCTTAGTTATTTGACAGATGACTTTTTAGAGTCCTCCAAGAAAATTGCCCACCTTTGGAAAGAAGAATTCGTTATCAGTGACAATCAAAAAACGAATGATTTAGTTTTTCTTCAGTTTGATAAAGAGGGCATTGAGCATTTTGCTTTCTTAAGACTAGCTCTAAAGGAGAGTTTAACGCATATTATTGATGATGGCGATAGCCCTCTGCGCCTGACACAAAATAATTTGCCATCTGCTGCACAAACACCAGATGAAGCTTTAATTATCAATCGTCAAAATCAGCAGTATTATCTTATTGAAAAGCGCATTAAGCATAATGGCTCTTTTGCTAATTATTTTTCAGAGAATCTTCTTCAAGTTAAGCCTGAACAATCAGTTAAAAAGTCCATTAAGATGATGGAACAGACAGCACAAAAAATTGCTGATAATTTCAATCAAGATGACTTTGCTTTTCATGCAAAGATGAAAGCCGCCATTTATAAAAATTTGGAAGAAGATCAGGAATTATCACCAGAAAAATTAGCCGATCAGCTCTTTGATTCCAATCTGACAGCGCGTTTAAATTTTATTGATGACTTGAAAGAAACAATCCCAGAGTCAATCAAAGTTTCTGATATCGATCATTCTCGTCAAACTAAAAAATTGGAGAATCAAAAACTGTCTCTTTCCAATGGAATTGAGCTTTTAGTACCCAATCATATCTATCAGGATGCAGAATCTGTTGAATTTATCCAAAACCAAAATGGAACTTATTCTATTTTGATCAAAAATATCGAAGACATACAAAGTAAATAATATGAAAAAAAAACTAATACGAATCATTCTTTTAGGTCTTCTGATTTTTATCGGATATCAAACTTTTACTACCTATCAGAATGTCAAAAAAGTACTTGCATACCGTCCAATGGTGCAGGAAGTTTTAGATGAAAATGATACTAAAACCAATGAAAATTTAGTTTTAGCCATGATTTATACAGAGACAAAAGGCAGAGAAGATGATTTAATGCAATCCAGCGAAAGTTCAAGTGGCATTGCTAATACTATTACCGATAGTCGTGAAAGCGTTAAACAAGGTATAACCGTTTTATCTGAAAATTTAGAAGAAGCGCAGAATAGGAATACGGATGTCTGGACGGCAGTGCAAGCTTATAATTTCGGTAAAAATTATATTCGTTATATTGCTAAGCATGGTGGTAAGAGTACAATAAAACTAGCCAAACGTTATTCCAAAGATGTTGTAGCACCAAGTCTAGGAAATAAAACAGGAGAAACATATCACTATCATAATTTAGTAGCATTCTATTATGGTGGCGGTGAGCTTTATAAAGACGGCGGCAATATCTATTACGCTAAGCAGGTCAAACTAAATCTCTCCTTAATTAAGTTTGTTGCTGCTTTCCAAAGAAAGTGAGTTTTATTGATGAGATCATTACTTATCTATTTTAAGGGGTATCTCAAAGAAACCATACTTGGCCCCGTCTTCAAACTTTTAGAGGCCTCTTTTGAATTGCTAGTTCCCTTGGTTATTGCCAAAATGGTTGATCGTTATATTCCTCATAATGATAAAAATCATCTTTATTTGATGATTTTCTTTCTGGTTTTATTAGCTTGTTCCAATATTACGGTGGCTCTTATTGCCCAATATTGTTCTGCTAAAGCAGCAGTGGGCTATACTAAACAGCTTAGTCAAAGTCTTTTTCAAAAAATCATGCGCTTGCCCAAGGAAAAACGCGATGAATTGACAACGTCAAGTTTAGTGACACGTTTGGTTAGTGATACCTTTCAAATTCAAACTGGCATTAATCAATTCTTGCGCCTTTTTCTTAGAGCACCGATTATTGTTTTTGGTTCAGTCTTGATGGCTTTTCTAATTAGTCCCAGAATTACCATTTGGTTTTTCCTGATGGTTTTTGTCCTTTTTGCTTTAGTTTATCTCATGTCTGTTGTGGTCAATCCTCTCTATGATAAGATTCGCCGTCTAACTGATAAAATTGTTGGTTTAACTCGTGAACAATTAGAAGGAAGTCGTGTTATTCGTGCTTTTGGTCAAATAAAAGCAGAAGAGGAGAATTTTCAAAAAACGAATCAAGATTATACGGATTGGCAAATTAAAACAGGTTATATTTCAACCTTAATAACCCCTCTGACCTATTTAGCTGTCAATGTCACCTTGATTGTTGTCATTTGGCAGGGACAAATTGCTATTTCACATCATTATTTGAGTCAGGGAATGCTAATTGCGCTAGTCAATTATTTGCTGCAAATTCTGGTAGAGCTTTTAAAATTAACGATGTTGGTTTCTTCTTTGAATCAGAGTTTCATCAGCGCTAGACGAATCACTCAGGTTTTTGACCAAGAGGAAGAAGATGTTTTAGCGCCTTTGCAATCTCAACTCGTTTCGGATGATGTCCTTGTTAAAGTGACAGATATGATTTTTTCCTATCCTCAGGCTGCTAAATCAGCTCTTGAAAGAATTTCTTTTGCTGTTGGACAAGGAGAATTCTTTGGTATTATTGGCGGGACTGGTTCTGGAAAGTCTAGTTTAATTCAAGTTCTGTTGCGTCTTTATCTCCCTCAAAAGGGCAATGTCGCTATTTTTAAGGACAAAAGGAGTGCAAAAACCATCAAGGAATGGCGAAATTGGGTTAGTCTGGTTCCTCAAAAGGCAGAACTCTTCACAGGAACGATTCGTTCTAACTTGTTGCTTAGTACAGAAAAACAAGTCAGTGATGAGCAGCTTTGGCAAGTGCTTGATATAGCTCAGGCTAGCGATTTTGTTAATCAGAAGCCAGGAAAACTTGATGCCCAAGTAGAAGCCTTTGGAAGGAATTTTTCAGGCGGACAGAGACAGCGTTTGACTATTGCTAGAGCTTTATTAAAAGAAGCACCTTTGCTGATACTAGATGACGCCACTTCAGCTCTTGATTATTTAACAGAAGCAAAACTCTTACAGGCTATCAAGGATAATTTTAAGAAGACGACACTTATTATGGTATCTCAAAGGACTAACAGTCTTTCTAAGGCAGATAATATTTTGGTTTTGGATCAAGGAAAGCAAGTGGCATTAGCCGATCATGCTAAGCTTTTACAAACCTGTTCGCTTTATCAGGAAATTCATTACTCGCAACATCCGCAAGAGGAGGTTGTCAAATGAAAGCTAGAAATAATAAAAATACCTTAAAGCGCTTGACTGCTGACTTTCTTAAGCAGAGAATTTTGGTTTTTCTTGCCTTATTGGGTACTTTGATTCAGGTCAGCCTAACGGTTTATCTCCCAGTTCTAATTGGGCAAGCAGTTGATGCTGTTCTTGCTAAAAATGTCCAGAAAATCTTACCGACAATCTTGATTAGCATGATTCTTGTTGTTGCCTTTAATACCATTATCCAATGGATCAATCCCTTGACTTACAATCGTTTGGTTTTCACTTATAGCCAGAAGCTTCGGCAGAATATCATTGAAAAACTTTATCGCCTCCCTTTATCTTATTTGGATAAGCATTCTTCAGGTGATTTAGTCAGTCGTATAACAACGGATGTTGAACAATTATCCAACGGACTTTTAATGGTTTTTAATCAGTTTTTCGTAGGTATTTTGACTATTTTGTTAACCATCATAACAATGGCGAAGCTAGACTTTTTTATGATGATTTTGGTACTGGTCTTAACACCACTTTCCTTATTTGTTGCTCGTTTTATTGCTCAAAAGAGTTATCATCTTTATCAAAGACAAACCAGAGCCAGAGGAGCATTTACTCAACATATTGAGGAGAGTCTTCGTCAGGAAAGTTTGATTCAAAGCTTCAATGCTCAAGATCAATTTATTCACACTTTTGATCATCTAAATAGCAAATATGCTAAGTATTCACAAGGTGCTATTTTCTATTCATCTACAGTCAATCCCGCGACACGTTTTATCAATGCCTTAATTTATGCGCTCTTAGCTGGTATCGGAGCATTACGCATTATGAATGGGAATTTTACTGTGGGGCAATTGACCACTTTCTTGAATTATGTCACTCAATATACCAAACCCTTTAATGACATTTCAGCCGTTCTATCTGAATTACAAAGTGCTTTAGCATGTGCAGAACGTCTCTATATGATTCTTGATGAAAAGGATGCTAAGGATGATGGCAAGAAAGAATTAGTCAGTGAATCTGTTAAAGGTGCTATTGCCTTTGATAAGATTAGTTTTGGTTATGATGAGAAACAAACTCTGATTAAGAATTTGTCTGTCAATATTCCACAAGGTTCCAAAGTGGCTATCGTTGGTCCTACAGGGGCTGGAAAATCAACTCTCATTAATTTGCTGATGCGATTTTATGATTTGCGAGAAGGGCAAATACTGCTAGATGGGCAAGCAATCACTGATTATAGTAAAGCTTCTTATCGTCAGCAGATTGGTATGGTCTTACAAGAAACTTGGTTGAAAACGGCTACTGTTTTGGAAAATATTGCCTTTGGTTATCCTGAAGCTAGCCGCGAGCAAGTGATTGCAGCGGCAAAAGCAGCTAATGCCGACTTTTTTATAAAACAACTTCCTCAAGGTTACGATACTTTTTTGGCCGATGCAGGAGAATCCCTATCACAAGGGCAAAGGCAATTGTTAACGATAGCACGAATTTTTGTTCATATTCCTAAAATATTAATCTTGGATGAAGCAACTTCCTCCATTGATACACGAACAGAAATCTTGGTCCAAGAAGCATTTGAAAAGCTTATGAAAGGACGGACCAGCTTTATTATTGCACATAGATTGTCAACTATTCAAAGCGCAGACCTTATCTTAGTTATGGTAGATGGCAATATTGTTGAACAAGGAAATCATAAAGACTTGATGCAGAAAAAAGGTGTCTATTATCAAATGCAGACAGCACAGGATAGCCTTGAAAGCTAATAATCATTATCATCAGATTAGTTTTTGATAGTAAATATTCTTTGAATATAAAGTAAAAAATGCTTGAAATACGTTTTAAACGCGTCATTCAAGCATTTTAATTTTAACTTAATTTTCAAGAAACGAAGCACTATCCGACGAAATCATTAATTTCTTTTTCGATATTAGCAATTTTAACTTGCGCATCTTCTGAATTATTACCAACAGTTGCGATGTAGAATTTGATTTTCGGCTCGGTACCTGAAGGACGGACAGCAATCCAAGACGCATCTGATAGGATATATTTAAGAACATTGCTTGGAGGAGTCGTTAATTTTTCAATACCATCAGCAGTTGTAGCAGTTTGAGCTTGGAAGTCTTCTAATTTAACGACATCTGTTGCGTTAAATTGTTTCGGAGCATCACCACGGAATTTATCCATGATTTTCTTAATCTCTGTAGCGCCATCAACACCTGACAGAGTAACTGAAATGGTTTTTTCAGCGAAGTAGCCGTATTCTTTGTAAATTTCATCAATGCCATCAGCAAGTGTTAAACCGCGTGAGCGATAGTAGGCTGCGATTTCAGCAACAATCAACACAGCTTGAATAGCGTCTTTATCACGAACAAAAGGTTTAATAAGGTAACCAAAGCTTTCTTCAAAGCCGAACATGTAAGTGTGGTTGTGTTTTTCTTCGAATTCTTGAATCTTTTCAGCAATGAATTTGAAACCAGTCAAGACATTAAACATAGTTGCGCCATAACTTTCAGCAATTTTGCTAACTAATTCAGTTGATACAATTGATTTACAAAGAGCAGCATTAGTAGGTAAACTTCCAGCCGTTTTGTGCGCTTCAAGAATGTACTTAGCGATGATAGCACCAATTTGATTGCCAGAAAGATTCTTATAAGATCCATCAGCTTGGCGAATTTCAACGCCAAGACGATCCGCATCTGGATCGGTTGCAACGAGAACATCAGCATCAACTTGACGTCCTAATTCTTCAGCCAAACGAAAAGCCTCTTGATTTTCTGGATTTGGTGATTTAACGGTTGAAAAATCAGGGTCTGGCACTGCTTGAGCTTCAACCACTTGAACAGAATCGAAACCAGCTTGTGCCAAAGCACGACGAGCCAGCATTTCACCAGTACCATGAAGTGGGGTGTAGACAATTTTCATGTCTTTACCGTACTCGTCAATCAATTTTTGGTTGATATTGACATCTTTAACTTCTTTGAGGTACTCAGTATCAACAGCTTCACCGATAACTTCAATTAATCCAGAAGCTTTGCTTTCTTCTAAATCAGCTAATTCAATTGAAAATGGATCATTAATGGCACGAATAAAATCTGTTAGAGCATCCGCATCAAAAGGAGGCATTTGTCCCCCATCTTCACCATAAACTTTGTAACCATTAAATGGTGCAGGGTTATGACTGGCTGTTACCATAATACCCGCAAAAGTTCCTAAATGGCGTACAGTAAATGATAACTCTGGAGTTGGACGAAGAGATTCAAAGACATAAGCTTTAATACCGTGTTTTGCTAAAACCTGAGCAGATTCAAAGGCGAATTCTTGAGAGAAATGACGGGAATCGTAAGCAATAGCAACACCGCGTTTTTTGACGTCGTCTCCTTTGGTTTCAATCAATTGGGCAAGTCCTTCAGTTGCTTGACGAACGACGTAAATATTGATCCGATTAGTTCCAGCGCCAATATAACCACGCATGCCCGCTGTACCAAACTCAAGATTAGTATAGAAAGCATCTTCCTTGGTCTTTTCATCCATTGCTAATAATTCTTGATGAAGATAGTCGGGAAGTTTAGCATAAGCTAACCATTTTTGATAATTTTCTTGATATACCAT

Protein sequences of DBSCAN-SWA_2

>NZ_LS483349|1031960:1040744|1033819_1034797_+|WP_002264268.1|DBSCAN-SWA
MMDLYLKKIVIHQFTPDDTELILSDKCLTITPNLDTYFRKKVGKVFSDEARRGQFDSGNVFLSYLTDDFLESSKKIAHLWKEEFVISDNQKTNDLVFLQFDKEGIEHFAFLRLALKESLTHIIDDGDSPLRLTQNNLPSAAQTPDEALIINRQNQQYYLIEKRIKHNGSFANYFSENLLQVKPEQSVKKSIKMMEQTAQKIADNFNQDDFAFHAKMKAAIYKNLEEDQELSPEKLADQLFDSNLTARLNFIDDLKETIPESIKVSDIDHSRQTKKLENQKLSLSNGIELLVPNHIYQDAESVEFIQNQNGTYSILIKNIEDIQSK
>NZ_LS483349|1031960:1040744|1035422_1037156_+|WP_002279945.1|DBSCAN-SWA
MRSLLIYFKGYLKETILGPVFKLLEASFELLVPLVIAKMVDRYIPHNDKNHLYLMIFFLVLLACSNITVALIAQYCSAKAAVGYTKQLSQSLFQKIMRLPKEKRDELTTSSLVTRLVSDTFQIQTGINQFLRLFLRAPIIVFGSVLMAFLISPRITIWFFLMVFVLFALVYLMSVVVNPLYDKIRRLTDKIVGLTREQLEGSRVIRAFGQIKAEEENFQKTNQDYTDWQIKTGYISTLITPLTYLAVNVTLIVVIWQGQIAISHHYLSQGMLIALVNYLLQILVELLKLTMLVSSLNQSFISARRITQVFDQEEEDVLAPLQSQLVSDDVLVKVTDMIFSYPQAAKSALERISFAVGQGEFFGIIGGTGSGKSSLIQVLLRLYLPQKGNVAIFKDKRSAKTIKEWRNWVSLVPQKAELFTGTIRSNLLLSTEKQVSDEQLWQVLDIAQASDFVNQKPGKLDAQVEAFGRNFSGGQRQRLTIARALLKEAPLLILDDATSALDYLTEAKLLQAIKDNFKKTTLIMVSQRTNSLSKADNILVLDQGKQVALADHAKLLQTCSLYQEIHYSQHPQEEVVK
>NZ_LS483349|1031960:1040744|1032560_1033823_+|WP_002279946.1|DBSCAN-SWA
MIFDKDNYEEYDREVWEAIHAEEKRQQNNIELIASENVVSKAVMKAQGSILTNKYAEGYPGRRYYGGTDYVDVVESLAIERAKRLFGAKYANVQPHSGSQANAAAYMALIKPGNTVMGLDLAAGGHLTHGSPVSFSGQTYNFIAYNVDPETEVLNYEQILKQAEEVQPKLIVAGASAYSHIIDFKKFRDIADQVGAKLMVDMAHIAGLVAADLHPNPVPYAHITTTTTHKTLRGPRGGLVLTNDEDLAKKINSAIFPGLQGGPLEHIVAAKAITFKENLDPAFKVYAQKIIENCQAMVEVFNAHEKFRVVSGASENHLFLVDVTQVVENGKVAQNILDDVHITLNKNSIPFEKLSPFKTSGIRIGTAAVTARGFGPEECRKVAELIVKTLENTENEAVLEEVRQEVKLLTDAFPLYENLV
>NZ_LS483349|1031960:1040744|1034798_1035413_+|WP_002262260.1|DBSCAN-SWA
MKKKLIRIILLGLLIFIGYQTFTTYQNVKKVLAYRPMVQEVLDENDTKTNENLVLAMIYTETKGREDDLMQSSESSSGIANTITDSRESVKQGITVLSENLEEAQNRNTDVWTAVQAYNFGKNYIRYIAKHGGKSTIKLAKRYSKDVVAPSLGNKTGETYHYHNLVAFYYGGGELYKDGGNIYYAKQVKLNLSLIKFVAAFQRK
>NZ_LS483349|1031960:1040744|1031960_1032551_+|WP_002279947.1|DBSCAN-SWA
MDKIEEALREGQAVVLPTETVYGLFAQALSKRAVDNVYDLKKRPREKAMNLNVASLEDILAFSKEAPAYLAELYKAFLPGPLTIVLKANEKVPAWINGGLSTVGFRVPAHPQTLAYIKQTGPLIGTSANLSGQASGLVYREIQEAFANRLLGIQDDKAIKGRDSTILDISSSRAKILRQGALTQDAIQAHVKDIRF
>NZ_LS483349|1031960:1040744|1037152_1038898_+|WP_002279944.1|DBSCAN-SWA
MKARNNKNTLKRLTADFLKQRILVFLALLGTLIQVSLTVYLPVLIGQAVDAVLAKNVQKILPTILISMILVVAFNTIIQWINPLTYNRLVFTYSQKLRQNIIEKLYRLPLSYLDKHSSGDLVSRITTDVEQLSNGLLMVFNQFFVGILTILLTIITMAKLDFFMMILVLVLTPLSLFVARFIAQKSYHLYQRQTRARGAFTQHIEESLRQESLIQSFNAQDQFIHTFDHLNSKYAKYSQGAIFYSSTVNPATRFINALIYALLAGIGALRIMNGNFTVGQLTTFLNYVTQYTKPFNDISAVLSELQSALACAERLYMILDEKDAKDDGKKELVSESVKGAIAFDKISFGYDEKQTLIKNLSVNIPQGSKVAIVGPTGAGKSTLINLLMRFYDLREGQILLDGQAITDYSKASYRQQIGMVLQETWLKTATVLENIAFGYPEASREQVIAAAKAANADFFIKQLPQGYDTFLADAGESLSQGQRQLLTIARIFVHIPKILILDEATSSIDTRTEILVQEAFEKLMKGRTSFIIAHRLSTIQSADLILVMVDGNIVEQGNHKDLMQKKGVYYQMQTAQDSLES
>NZ_LS483349|1031960:1040744|1039028_1040744_-|WP_002264266.1|DBSCAN-SWA
MVYQENYQKWLAYAKLPDYLHQELLAMDEKTKEDAFYTNLEFGTAGMRGYIGAGTNRINIYVVRQATEGLAQLIETKGDDVKKRGVAIAYDSRHFSQEFAFESAQVLAKHGIKAYVFESLRPTPELSFTVRHLGTFAGIMVTASHNPAPFNGYKVYGEDGGQMPPFDADALTDFIRAINDPFSIELADLEESKASGLIEVIGEAVDTEYLKEVKDVNINQKLIDEYGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQAVPDPDFSTVKSPNPENQEAFRLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYKNLSGNQIGAIIAKYILEAHKTAGSLPTNAALCKSIVSTELVSKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLIVAEIAAYYRSRGLTLADGIDEIYKEYGYFAEKTISVTLSGVDGATEIKKIMDKFRGDAPKQFNATDVVKLEDFQAQTATTADGIEKLTTPPSNVLKYILSDASWIAVRPSGTEPKIKFYIATVGNNSEDAQVKIANIEKEINDFVG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002279947.1|1031960_1032551_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	8.1e-16	33.2
WP_002279946.1|1032560_1033823_+	serine hydroxymethyltransferase	A0A219YB23	Aeromonas_phage	4.8e-98	51.8
WP_002264268.1|1033819_1034797_+	nucleoid-associated protein	NA	NA	NA	NA
WP_002262260.1|1034798_1035413_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.2e-22	37.6
WP_002279945.1|1035422_1037156_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.3e-39	25.8
WP_002279944.1|1037152_1038898_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.9e-53	29.2
WP_002264266.1|1039028_1040744_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	7.5e-272	82.5

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NZ_LS483349|1175839:1182689|DBSCAN-SWA
ATCAAGCCACTTCTTCTGTAAATTGACTATTATAGAGATCGGCATAGAAGCCATTTTCTGCCATCAATTGGTCATGGCTGCCTTGTTCAATAATATTACCATCTCTCATGACAAGAATAAGATCAGCATTGCGAATAGTTGACAGACGATGGGCAATAACGAATGATGTCCGCCCCTCCATCAAATGATCCATAGCCCTTTGAATAAGTTCTTCCGTACGAGTATCAACAGAGGAAGTTGCTTCATCAAGTATCAGAAGCGGTGCATCTTTAAGGAGAGCACGTGCAATGGTCAAGAGTTGTTTTTGACCGACTGATAAGGTGACCGAATCATCTAAAACAGTATCATAACCCTTAGGTAAAGTCTTGATGAAATGATGAACACCAACTGCCTTAGCTGCTGCAATCACTTGCTCATCAATAATATGTTTTTGATTATAAATCAGATTTTCCTTAACTGTACCTTCAAAGAGCCAAGTATCTTGGAGTACCATGGCAAAAGCATCATGCACTTCTTCTCGTGTCATATCATGGATATTAACTCCATCAATAGAAATCATCCCTCTATCAACCTCATAGAAACGCATAAGTAAGTTAACAATCGTTGTCTTACCCGCACCAGTCGGTCCCACAATAGCAATTTTTTGACCAGCCTTAGCATGAGCCGAGAAATCATGAATAATAGTTTTATCAGGACTATAACCAAAGAAAACATTGTCAAAATTAACATTTCCTTCAACTTTTTCAAGTTGTTTAACTTTATGGTTTTCGTCTTCTATTTCTTCCTCATCAAGAAATTCAAAGACACGTCCCATAGCAGCATTAGCTGATTGCAATTGAGTGATTCCTTGAGCAATCTGCGCAATGGGCTGAGTAAAAATACGGACGTAAGTCATAAAGGCAACAATCGTTCCCATAGTAATATCGCCGTTAATAGCCATGGTAGCACCGACAATACAGACCATGACATACCCAAAATTTCCGATGAATTGCATAAGGGGCATCATAATTCCAGAAAAGAATTGTGATTTCCACATACTTGCAAATAATTGGTCATTCAAGTTTTCAAACTGCTTCTTGCTTTGCTGAATCGCATTGTAACTAGAAACCACATTATGACCTGAATAGACCTCTTCAACATAACCGCTGACATCGGCTAGATTAGCTTGTTGCTTTTTAAAAAGCGGCTGGCTCTTGGCCATGATAACAGTGGATAACACAAAACCAGCAAAAACAGACAAAATAGCGGTCGCTGCAAGAGCTCCATTGGTTTTAATCATCATGAAAATAGAGCCAATCAGGAGAATTATAGCTGCTACCATTGAAACTAAACTTTGGTTGAAAGACTGTGTCATTAAATCCACATCATTGGTCACTCGAGACAAGGTATCTCCTTGTGAATGGCTATCAAAATATTTGAGCGGTACCTTATTGATTTTATCTGCAATGGCATTGCGCAGACGTTGCGAAAACTTTTGAATCAAAGTGGACACAATAAAGCTAGCAGTATAAGAAACCAAAGCACCAGCAAAGTATAAGAGAGCCAAGGTTAGAGCAATCTCACCGATTTTATCTAAATCAATTTTTCCTGCCAGCCCTTTGGTCATGGTATCTGTCATCTCTTTCAGCCGGTCAGGTCCAATAACAGTAATCGTACTTGAAACGATAGTAAAAATGACAGCAAGTCCAAATAAAGCCTTATAGCCTTTAAGGTAAGGAGCCATTTGGCTTAATAATGATTTCTTCTTATTTTCCATTTTCTAACTCCTCCTTAGATAGTTGTGAATAAGCAATTTCTTGATAAATATCGTTATTAGCCAGTAATTCCTTGTGTGTTCCTTGACCAACAACCTTTCCTTGATCTAAGACTAAAATATGATCAGCATCCATAATAGTTGAAATACGTTGGGCGACAATCAGCTTAGTCATGTCTTTGGTTTTCTTTGCCAAATCATTTCGCAGAATGCGATCCGTCTTATAATCAAGAGCTGAGAAGGAGTCATCAAAAATAAGAATTTCTGGTTTGCGTGCAAGTGCACGGGCAATAGCTAAGCGCTGCTTTTGACCGCCAGAGAAGTTGGTACCGCCTTGAGCTACCTCGGTATCCAGACCCTTTTCTTTTTCTTCAACAAAGTTTTTGGCTTGGGCTAGTTCAAGAGCCTCCCAAATTTTAGCATCATCAAGCGGCGCTTGATCGCTTTGCCCAAATGCAATATTAGAACGAATGGTCCCACTAAAAAGCACTGCCCTTTGCGGAATATAGCCGACTTTATTGTTGAGGTCATCATGGCTGTAATCTTGCACTTTGATTCCATCTATCTTAATCCAACCTTCTGTAGCATCATAAAAACGAGGAATCAGATTAACAAGAGTTGATTTTCCTGAGCCAGTGGAACCAATAAAAGCAACTGTCTCACCAGCTTTGGCACTGAAAGACACATGCTCAATAACCGCACGAGAATTTTTACTGTAACGAAACGATACATCATGAAATTCGACTTCTCCTTTTCGAGCATTGTCTGCTTTAGAATATTCTTTGAAGTGTACAGATGAGTTAAGCGCCAATACTTCATTAATTCGTTTGGCAGAAACTAAAGCACGCGGTAAAATGATAAAGACAGCGACCATCATCATAAAACCGACAACAACCTGCATGGCATAAGATGAAAAGACAACCATATCACTAAAAACACTGATACGATCAGCAATAGCTCCTTTAGCAGCTGTCACACTCGTCATAGGAATTTTAATATCATTGAGCAGGTAAGCTCCAATCCAATAAATAGCTAAAGTTAGACCACTGGAAACAACTGTCATGACAGGATTCATTAGCGACATCAGACGATAGACCAATAAATTCAATTTCGTCAGGTTTTTATTTTCCCGCTTAAATTTAGTGTCCTGATAATCTTCTGCATTGTAAGCCCGAACAACACGAACACCAGTCAGAGATTCACGGGTTGTAGAATTTAGAGCATCCGTCAAGCTCTGCACCTGACGCTGTCTTGGAAAAGCGACAAACATCAAAACAGACAGCATAATAAAGACAATTAAAACGGCAACACCGACTGCTCCTGTCCATTCATCGCTTTTACCCCAGATTTTAGTCAAGGCCCAAACAGCCATGATTGGACCGCGTGTCACCACTTGCATTCCCATAACGATCATGATTTGCAACTGTGTCAAATCATTAGTCGTACGCGTTAGAAGGCTGGGAATGGAAAATTTCTTGATTTCCGCCTCTGAATAATCCATAACCCGATTGAAAATATCAGATCGAAGACGGGTCGTAAAGCTAGCAGCTGTTCTTGAAGCTAAAAAACCAACTAGAACGGCCATAAAAAAGCTCCCAAATGAAAACATGAGCATCTTAGATCCCGGATCCATAATATCTGAGGCGGTCGTTCCCTTAGTCTGCAGCAAGGTTGTAATGTTGGACATATATTCGGGCGTCTTCAAATCCATCCAGACAGCCAAACAGATAAAGGCAGTACTAAGGAGAACCATGCCCCATTCTTTAGCATTTAGACGTTTAAAAATTTTAAACATGAATTACTCCTTCTTTTCTAAATTTTGTTTGATTTGTTTAAAAACCTTCCGAGCAACTGATAAGTCTTCCTGACTAATATCTTTTAGAAGCAACTTTTTAAGATCTGTTAAAAAAACAGTTATTTTTCCAGCTTTTTCCTGACCTAATGGCGTTAAAACAATTTGCTTGTATCGTCTGTCTTTTCTGGAAGGAATAACAGAAATAAAACCATTTTTTTCCATTCGTTTAATGAGATTACTGGTCACAGATTTTGAGATATCTAACCTTTTTTCAATATCTTTAATAAAAATTTCCTTTCCTTGATTATCCTTTAAAAACATAACTGTCCATCCCTGAGGTCCGGACAGATGTTCAACACCATGGCTTTTGGATAATTCTTGAATATATCTTTCTGTTGCTGTAATGAGGTTTTTAAATTCACTAAAAGGCTCCTTCATAAAAACACCTCACTTTTTATGAGAATATTATAATAGTTCTCATGAAAACTATTATAATGATTCCTTAAACTATTGTCAAGAAAAAAGTTTCTATGAGAACTAATTTAATTTTTTATAGCTTGATGGTGATAAAGTCACTTTAAACGATTGCTTTTTCGCTGTAGTGAAAGTGCTCAAACCGCTTATAGTTCTATCATGAGGTGTTGGTAAGACCTAGGGGCGCCAAAAAGAATGGAACTCCCTTGAATTTCTAAAATAGTCCGCTGGACTATTCACTTTTCGCCTTCATTACTTAAGAAAAGCCACAACCATAAAAAGAATAATTCATTTCCAAACAAGTCTAATCCTTCTGACTACTTTCTAAGACTGGCTTTATTGAACAAATTTGCTTTTTCCCTATTTTCATGTTACCATATTGAAGAATTACATAAGGATGTTTGGGAGAAGCCATCTATAAAAAAAACCAGCCTATTATTTGGCAGCTCCTATTTTTATATTAGGAGCTTTTTTACTGCTCAAAATTATCCTTAACGAAATTTAAAGGAGTTTTTATGAAACGTCAATCAGCTCTTGTCGTCTTTAGCGGTGGTCAAGATTCAACTACCTGCCTTTTTTGGGCAATGAAGCATTATGAATATGTCGAAACAGTTACCTTTTCCTATGGCCAACGTCACAGTCAAGAATTAGAGGTTGCCAAGGAAATTGCTGCAGAACAAGGCGTGAAACACCATATCCTTGATATGTCTTTACTGGGACAAATAACAGAAAATGCCTTAACTTCTGACATAGCTATAGAAACAAAAGACGGTGAAGTCCCCAATACTTTTGTTGATGGCAGAAATCATCTCTTTCTTTCCTTTGCTGCAGTCCTTGCCAAACAGCGCAAGATAAGAGATATTGTCACCGGAGTCTGTCAAACAGATTTTTCAGGTTATCCTGACTGTCGTGATGTTTTTGTCAAGTCTCTCAATGTTACCTTAAATCTTGCTATGGATTATGAATTCGTCATTCAAACGCCTCTGATGTGGCTAGACAAGGCCGAAACATGGGAATTGGCAGATCAGCTAGGTAAATTTGATTATGTTCGTCAAAAGACTCTGACCTGCTACAATGGAATTCGAGGAACTGGCTGCAGACAATGCCCTGCCTGCCATTTACGTCAAGCTGGACTTGAAAAATATCTTAGTCAGAAAGGAAAAAATTAATGTTCTTAGCGCCAAAAGAAATTAAAAACGAGACAGGAGAATCACTTCTTTATTGTCCCAAACGCGTTCTTGTATCTAAAGAATTCACCTTTAATGCTGCCCACCATCTCTTCAATTATGAAGGGAAATGCAAAGCCTTACATGGACATACTTATCATTTACAAGTTGCTGTCAGTGCTTTTCTTGATGAACGCGGAATGACTTATGATTTTAGAGAGTTGAAAAGGATCTACCAAGAATATTTAGAACCAAAACTAGACCACCGCTACCTTAATGAAAGTCTGCCCTACATGAATACAACTGCTGAAAATATGGTTTATTGGATTTACAAAACAGTCGAGAAAGCTTTAACTGACGAGCGCGGTTTACAAATGGAACATGTTCGCCTTTATGAAACACCCTCAGCTTATGCTGAATTTAGAAGAGAATGGGATTTACAAGCATGAAAAAACAACGTCTGTTAAAGTTACCCGTTTTAGAAATCTTTGGTCCAACTTTTCAAGGAGAAGGCAGGGCCATCGGTCAAAAAACTATGTTTGTTCGTACAGGTGGCTGTGATTATCACTGCGATTGGTGCGATTCTGCCTTTACTTGGGACGGTTCTGAAAAGCCAACTATGATGACCAGTGACCAAATTATTGAAGCATTAGATAAACTTGGTACTTATGATTATGTGACACTCTCTGGCGGCAATCCTTGCCTTCTGGCTGCTAATATGGCCCAGCTCGTTAGGAAACTCAAAAAAAGACAAGTCACTCTTGCTGTCGAAACTCAAGGTTCTCGCTGGCAAGAATGGCTAAAAGCCATTGATCAAGTAACTTTAAGCCCTAAACCGCCGTCCAGCAAAATGAAAGTAAACTTACAAACCCTTGATTTTATCGTATCAAATTTAGATCCACAAAAGGTAACTTACAAAATCCCTATCTTTGACGAAGACGATTTAAAATTCGCCCAAATGATCCAAGGACGCTATCAGCCAGATGTCCTTTATCTGTCTGTTGGAAATCCAGAGCCCAAAGCCAGTGGTGATATTGTCCAAAATCAGCTGAAACGTTTAAAAGAGTTATGGGAACACATTGCTCAAGATGATTCTTGGGGAAATGTCCGCGTCTTACCGCAATTGCATACACTTGTTTATGATAATAAACGTGGTGTCTAGAAAGGAACAAATATGTCACAAAAAGAAATAAAAGACTTAACTCTTTTGGGAAATCAAAAGACCAATTACAACTTTGATTATGATCCCAATATTTTGGAAGCTTTCGATAATCGCCATCAAGATAACGATTATTTTATCAAGTTTAACTGTCCAGAATTTACCTCTCTGTGTCCTATAACGGGGCAGCCTGATTTTGCAACTATCTATCTCTCTTATATTCCAGATAAAAAATGCGTTGAATCCAAATCACTCAAACTTTATCTCTTTAGTTACCGTAACCATGGTGATTTTCATGAGAATTGTATCAATACGATTGGTAAAGATCTCGTCGATCTATTACAGCCTCGTTATCTAGAAGTCTGGGGCAAATTTACACCGCGTGGCGGTATCTCTATTGATCCTTATTATAATTACGGACGCCCAAATACCAAATATGAAGAAATGGCAGCTTATCGTTTGATGAACCACGATCTTTACCCAGAAACAATTGATAATCGTTAA

Protein sequences of DBSCAN-SWA_3

>NZ_LS483349|1175839:1182689|1179389_1179824_-|WP_002263292.1|DBSCAN-SWA
MKEPFSEFKNLITATERYIQELSKSHGVEHLSGPQGWTVMFLKDNQGKEIFIKDIEKRLDISKSVTSNLIKRMEKNGFISVIPSRKDRRYKQIVLTPLGQEKAGKITVFLTDLKKLLLKDISQEDLSVARKVFKQIKQNLEKKE
>NZ_LS483349|1175839:1182689|1181028_1181475_+|WP_002263290.1|DBSCAN-SWA
MFLAPKEIKNETGESLLYCPKRVLVSKEFTFNAAHHLFNYEGKCKALHGHTYHLQVAVSAFLDERGMTYDFRELKRIYQEYLEPKLDHRYLNESLPYMNTTAENMVYWIYKTVEKALTDERGLQMEHVRLYETPSAYAEFRREWDLQA
>NZ_LS483349|1175839:1182689|1175839_1177594_-|WP_002280030.1|DBSCAN-SWA
MENKKKSLLSQMAPYLKGYKALFGLAVIFTIVSSTITVIGPDRLKEMTDTMTKGLAGKIDLDKIGEIALTLALLYFAGALVSYTASFIVSTLIQKFSQRLRNAIADKINKVPLKYFDSHSQGDTLSRVTNDVDLMTQSFNQSLVSMVAAIILLIGSIFMMIKTNGALAATAILSVFAGFVLSTVIMAKSQPLFKKQQANLADVSGYVEEVYSGHNVVSSYNAIQQSKKQFENLNDQLFASMWKSQFFSGIMMPLMQFIGNFGYVMVCIVGATMAINGDITMGTIVAFMTYVRIFTQPIAQIAQGITQLQSANAAMGRVFEFLDEEEIEDENHKVKQLEKVEGNVNFDNVFFGYSPDKTIIHDFSAHAKAGQKIAIVGPTGAGKTTIVNLLMRFYEVDRGMISIDGVNIHDMTREEVHDAFAMVLQDTWLFEGTVKENLIYNQKHIIDEQVIAAAKAVGVHHFIKTLPKGYDTVLDDSVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQRAMDHLMEGRTSFVIAHRLSTIRNADLILVMRDGNIIEQGSHDQLMAENGFYADLYNSQFTEEVA
>NZ_LS483349|1175839:1182689|1180375_1181029_+|WP_002263291.1|DBSCAN-SWA
MKRQSALVVFSGGQDSTTCLFWAMKHYEYVETVTFSYGQRHSQELEVAKEIAAEQGVKHHILDMSLLGQITENALTSDIAIETKDGEVPNTFVDGRNHLFLSFAAVLAKQRKIRDIVTGVCQTDFSGYPDCRDVFVKSLNVTLNLAMDYEFVIQTPLMWLDKAETWELADQLGKFDYVRQKTLTCYNGIRGTGCRQCPACHLRQAGLEKYLSQKGKN
>NZ_LS483349|1175839:1182689|1182200_1182689_+|WP_002280032.1|DBSCAN-SWA
MSQKEIKDLTLLGNQKTNYNFDYDPNILEAFDNRHQDNDYFIKFNCPEFTSLCPITGQPDFATIYLSYIPDKKCVESKSLKLYLFSYRNHGDFHENCINTIGKDLVDLLQPRYLEVWGKFTPRGGISIDPYYNYGRPNTKYEEMAAYRLMNHDLYPETIDNR
>NZ_LS483349|1175839:1182689|1177583_1179386_-|WP_002280031.1|DBSCAN-SWA
MFKIFKRLNAKEWGMVLLSTAFICLAVWMDLKTPEYMSNITTLLQTKGTTASDIMDPGSKMLMFSFGSFFMAVLVGFLASRTAASFTTRLRSDIFNRVMDYSEAEIKKFSIPSLLTRTTNDLTQLQIMIVMGMQVVTRGPIMAVWALTKIWGKSDEWTGAVGVAVLIVFIMLSVLMFVAFPRQRQVQSLTDALNSTTRESLTGVRVVRAYNAEDYQDTKFKRENKNLTKLNLLVYRLMSLMNPVMTVVSSGLTLAIYWIGAYLLNDIKIPMTSVTAAKGAIADRISVFSDMVVFSSYAMQVVVGFMMMVAVFIILPRALVSAKRINEVLALNSSVHFKEYSKADNARKGEVEFHDVSFRYSKNSRAVIEHVSFSAKAGETVAFIGSTGSGKSTLVNLIPRFYDATEGWIKIDGIKVQDYSHDDLNNKVGYIPQRAVLFSGTIRSNIAFGQSDQAPLDDAKIWEALELAQAKNFVEEKEKGLDTEVAQGGTNFSGGQKQRLAIARALARKPEILIFDDSFSALDYKTDRILRNDLAKKTKDMTKLIVAQRISTIMDADHILVLDQGKVVGQGTHKELLANNDIYQEIAYSQLSKEELENGK
>NZ_LS483349|1175839:1182689|1181471_1182188_+|WP_002263289.1|DBSCAN-SWA
MKKQRLLKLPVLEIFGPTFQGEGRAIGQKTMFVRTGGCDYHCDWCDSAFTWDGSEKPTMMTSDQIIEALDKLGTYDYVTLSGGNPCLLAANMAQLVRKLKKRQVTLAVETQGSRWQEWLKAIDQVTLSPKPPSSKMKVNLQTLDFIVSNLDPQKVTYKIPIFDEDDLKFAQMIQGRYQPDVLYLSVGNPEPKASGDIVQNQLKRLKELWEHIAQDDSWGNVRVLPQLHTLVYDNKRGV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002280030.1|1175839_1177594_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.9e-42	27.6
WP_002280031.1|1177583_1179386_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.9e-32	24.7
WP_002263292.1|1179389_1179824_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002263291.1|1180375_1181029_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.7e-60	52.4
WP_002263290.1|1181028_1181475_+	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	1.1e-41	60.6
WP_002263289.1|1181471_1182188_+	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	4.8e-63	48.4
WP_002280032.1|1182200_1182689_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.6e-47	57.9