CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483357	Streptococcus pyogenes strain NCTC8326 chromosome 1	2 crisprs	DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,csn2,cas9,csm6,DinG,csa3	1	4	6	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483357_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483357_1

562575-562935

TypeI

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CRT

5 spacers

cas2,cas1,cas4,cas7,cas8c,cas5

The CRISPR arrays of NZ_LS483357_1

>merge|NZ_LS483357|1|562575-562935|PILER-CR,CRISPRCasFinder,CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAATTACTAGCGTTGAGATAGCCGGTATTAATCTTACCGTCTCACCCTTCATGGGTGAGTGGATTGAAATATTTCGTCACCTCCTCAATCAATAATAGAGTCAGTCTCACCCTTCATGGGTGAGTGGATTGAAATCTAAGATGATACCAGTTACAATACCGATTTTAAGCGTCTCACCCTTCATGGGTGAGTGGATTGAAATAAATAATTACATGACTAGCCAATACACCCACATAGTCTCACCCTTCATGGGTGAGTGGATTGAAATTTCATGAGCTTCTTTACTCTCAAAGTAAGAGTGGTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_LS483357|1|1|562575-562935|PILER-CR
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_LS483357|1|1|562575-562935|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

>NZ_LS483357|1|1|562575-562935|CRT
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TACTAGCGTTGAGATAGCCGGTATTAATCTTACC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	ATTTCGTCACCTCCTCAATCAATAATAGAGTCA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	CTAAGATGATACCAGTTACAATACCGATTTTAAGC
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	AAATAATTACATGACTAGCCAATACACCCACATA
GTCTCACCCTTCATGGGTGAGTGGATTGAAAT	TTCATGAGCTTCTTTACTCTCAAAGTAAGAGTG
GTCTCACCCTTCATGGGTGAGTGGATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483357.1\|WP_002989018.1\|550451_550847_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_LS483357.1\|WP_011528826.1\|564483_565590_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483357.1\|WP_002983795.1\|570811_571492_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483357.1\|WP_111678877.1\|563094_563805_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483357.1\|WP_002989044.1\|562132_562426_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LS483357.1\|WP_011528822.1\|569313_570030_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LS483357.1\|WP_002983750.1\|550176_550431_+\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073
NZ_LS483357.1\|WP_011528824.1\|566414_568148_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483357.1\|WP_002983792.1\|570196_570670_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483357.1\|WP_011284984.1\|560425_561100_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_LS483357.1\|WP_011528823.1\|568220_569300_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483357.1\|WP_011528831.1\|556947_557676_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483357.1\|WP_011528830.1\|557675_559571_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|273839
NZ_LS483357.1\|WP_011528834.1\|552013_554662_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483357.1\|WP_011284983.1\|561096_562122_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483357.1\|WP_011528827.1\|563817_564441_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483357.1\|WP_021299338.1\|551448_552012_+\|ATPase-AAA	unknown	unknown	gnl\|CDD\|223637
NZ_LS483357.1\|WP_011528825.1\|565677_566418_+\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483357.1\|WP_002983803.1\|571765_573001_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_LS483357.1\|WP_021299321.1\|559575_560424_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175

Protein	Function_ID	Function_description	E-value
NZ_LS483357.1\|WP_002989018.1\|550451_550847_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000151325
NZ_LS483357.1\|WP_011528826.1\|564483_565590_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	1.00806e-161
NZ_LS483357.1\|WP_002983795.1\|570811_571492_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
NZ_LS483357.1\|WP_111678877.1\|563094_563805_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.22933e-43
NZ_LS483357.1\|WP_002989044.1\|562132_562426_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
NZ_LS483357.1\|WP_011528822.1\|569313_570030_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	2.72904e-105
NZ_LS483357.1\|WP_002983750.1\|550176_550431_+\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47
NZ_LS483357.1\|WP_011528824.1\|566414_568148_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	4.25578e-64
NZ_LS483357.1\|WP_002983792.1\|570196_570670_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.23847e-66
NZ_LS483357.1\|WP_011284984.1\|560425_561100_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	3.0744e-43
NZ_LS483357.1\|WP_011528823.1\|568220_569300_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.76739e-34
NZ_LS483357.1\|WP_011528831.1\|556947_557676_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.63992e-116
NZ_LS483357.1\|WP_011528830.1\|557675_559571_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
NZ_LS483357.1\|WP_011528834.1\|552013_554662_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483357.1\|WP_011284983.1\|561096_562122_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483357.1\|WP_011528827.1\|563817_564441_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.52991e-34
NZ_LS483357.1\|WP_021299338.1\|551448_552012_+\|ATPase-AAA	gnl\|CDD\|223637	COG0563, Adk, Adenylate kinase and related kinases [Nucleotide transport and metabolism].	0.00782951
NZ_LS483357.1\|WP_011528825.1\|565677_566418_+\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	1.6473e-83
NZ_LS483357.1\|WP_002983803.1\|571765_573001_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_LS483357.1\|WP_021299321.1\|559575_560424_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	6.49658e-159

>NZ_LS483357.1|WP_002989044.1|562132_562426_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LS483357.1|WP_011284983.1|561096_562122_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LS483357.1|WP_011284984.1|560425_561100_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMTSEEMDL
>NZ_LS483357.1|WP_021299321.1|559575_560424_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLEGSINAYFAEKTGFSQEDAEAIKEVLVSLCENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LS483357.1|WP_011528830.1|557675_559571_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMGQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIAPDYQHNQLKVIYFDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITLATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKWQETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLIDGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>NZ_LS483357.1|WP_011528831.1|556947_557676_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPASKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_LS483357.1|WP_011528834.1|552013_554662_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIVRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKEKDKQADYQAKYDATQERIAEMQKIKS
>NZ_LS483357.1|WP_021299338.1|551448_552012_+|ATPase-AAA
MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPWSQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLTRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483357.1|WP_002989018.1|550451_550847_+|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_LS483357.1|WP_002983750.1|550176_550431_+|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>NZ_LS483357.1|WP_111678877.1|563094_563805_+|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLVTIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHMLLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483357.1|WP_011528827.1|563817_564441_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDEMSTSKDKSMMADKTSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483357.1|WP_011528826.1|564483_565590_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPLSPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHAFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483357.1|WP_011528825.1|565677_566418_+|response-regulator
MYSLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLDLSKKTETIQELVEQPQKEVSAIAMAIHEQLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_LS483357.1|WP_011528824.1|566414_568148_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETISVLAKNSEIKDFASQIHQENDKQVFQLMKMVLATNSDLQAAVLVTKDGRTVSTNPQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSSKKEWVVSVTQEVVDAVGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRVQRQIFWSFLGTGLLACLICSFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGSPELTDLVQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_LS483357.1|WP_011528823.1|568220_569300_+|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKITDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYKDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_LS483357.1|WP_011528822.1|569313_570030_+|B3/4-domain-containing-protein
MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPAGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNSTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHAITSVHVLDKDNPHVPLFTEN
>NZ_LS483357.1|WP_002983792.1|570196_570670_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483357.1|WP_002983795.1|570811_571492_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_LS483357.1|WP_002983803.1|571765_573001_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Crispr_ID: NZ_LS483357_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483357_2

728381-728502

Orphan

Consensus_repeat	Method
GCGGATCAAGCAGACGCTTTACAATCAGAAGAAGCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483357_2

>merge|NZ_LS483357|2|728381-728502|CRISPRCasFinder
GCGGATCAAGCAGACGCTTTACAATCAGAAGAAGCTGCAGTAGTTCAATCAGATACCGCTGCTAGTGACGCCTTAGAAGCATTGGCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTGC

>NZ_LS483357|2|2|728381-728502|CRISPRCasFinder
GCGGATCAAGCAGACGCTTTACAATCAGAAGAAGCTGC	AGTAGTTCAATCAGATACCGCTGCTAGTGACGCCTTAGAAGCATTG
GCGGATCAAACAGACGCTTTACAATCAGAAGAAGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483357.1\|WP_011888813.1\|739152_740637_-\|DUF1846-domain-containing-protein	unknown	unknown	gnl\|CDD\|184220
NZ_LS483357.1\|WP_002984060.1\|716690_717317_+\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NZ_LS483357.1\|WP_011528732.1\|736240_737632_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NZ_LS483357.1\|WP_021299177.1\|721106_722048_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	unknown	unknown	gnl\|CDD\|237010
NZ_LS483357.1\|WP_011528740.1\|725099_726296_+\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NZ_LS483357.1\|WP_044555083.1\|729528_730812_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NZ_LS483357.1\|WP_002984100.1\|730827_731688_+\|methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|180918
NZ_LS483357.1\|WP_002989257.1\|717396_717660_+\|DUF1294-domain-containing-protein	unknown	unknown	gnl\|CDD\|225863
NZ_LS483357.1\|WP_136280421.1\|720928_721132_+\|DUF3272-domain-containing-protein	unknown	unknown	gnl\|CDD\|314526
NZ_LS483357.1\|WP_002989260.1\|717712_718522_-\|PrsW-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|225217
NZ_LS483357.1\|WP_111678880.1\|722250_724563_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|227223
NZ_LS483357.1\|WP_011528730.1\|738646_739048_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_LS483357.1\|WP_002984106.1\|734041_734533_+\|shikimate-kinase	unknown	unknown	gnl\|CDD\|234654
NZ_LS483357.1\|WP_011528734.1\|732765_734049_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|235037
NZ_LS483357.1\|WP_011528735.1\|731689_732655_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NZ_LS483357.1\|WP_011528733.1\|734740_736192_+\|LCP-family-protein	unknown	unknown	gnl\|CDD\|224235
NZ_LS483357.1\|WP_011017927.1\|718666_719164_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NZ_LS483357.1\|WP_021299185.1\|719163_720834_+\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
NZ_LS483357.1\|WP_011528739.1\|726469_727729_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NZ_LS483357.1\|WP_002984095.1\|728977_729520_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584

Protein	Function_ID	Function_description	E-value
NZ_LS483357.1\|WP_011888813.1\|739152_740637_-\|DUF1846-domain-containing-protein	gnl\|CDD\|184220	PRK13663, PRK13663, hypothetical protein; Provisional.	0
NZ_LS483357.1\|WP_002984060.1\|716690_717317_+\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	8.03786e-135
NZ_LS483357.1\|WP_011528732.1\|736240_737632_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	1.50844e-179
NZ_LS483357.1\|WP_021299177.1\|721106_722048_-\|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	9.87137e-143
NZ_LS483357.1\|WP_011528740.1\|725099_726296_+\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NZ_LS483357.1\|WP_044555083.1\|729528_730812_+\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NZ_LS483357.1\|WP_002984100.1\|730827_731688_+\|methionyl-aminopeptidase	gnl\|CDD\|180918	PRK07281, PRK07281, methionyl aminopeptidase.	0
NZ_LS483357.1\|WP_002989257.1\|717396_717660_+\|DUF1294-domain-containing-protein	gnl\|CDD\|225863	COG3326, COG3326, Predicted membrane protein [Function unknown].	6.73707e-28
NZ_LS483357.1\|WP_136280421.1\|720928_721132_+\|DUF3272-domain-containing-protein	gnl\|CDD\|314526	pfam11676, DUF3272, Protein of unknown function (DUF3272). This family of proteins with unknown function appears to be restricted to Streptococcus.	8.3117e-22
NZ_LS483357.1\|WP_002989260.1\|717712_718522_-\|PrsW-family-intramembrane-metalloprotease	gnl\|CDD\|225217	COG2339, prsW, Membrane proteinase, regulator of anti-sigma factor [Posttranslational modification, protein turnover, chaperones].	2.0574e-58
NZ_LS483357.1\|WP_111678880.1\|722250_724563_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|227223	COG4886, COG4886, Leucine-rich repeat (LRR) protein [Function unknown].	4.09787e-25
NZ_LS483357.1\|WP_011528730.1\|738646_739048_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	5.35336e-24
NZ_LS483357.1\|WP_002984106.1\|734041_734533_+\|shikimate-kinase	gnl\|CDD\|234654	PRK00131, aroK, shikimate kinase; Reviewed.	1.52823e-63
NZ_LS483357.1\|WP_011528734.1\|732765_734049_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|235037	PRK02427, PRK02427, 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional.	0
NZ_LS483357.1\|WP_011528735.1\|731689_732655_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	1.21545e-55
NZ_LS483357.1\|WP_011528733.1\|734740_736192_+\|LCP-family-protein	gnl\|CDD\|224235	COG1316, LytR, Transcriptional regulator [Transcription].	7.61998e-64
NZ_LS483357.1\|WP_011017927.1\|718666_719164_+\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	2.03379e-83
NZ_LS483357.1\|WP_021299185.1\|719163_720834_+\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
NZ_LS483357.1\|WP_011528739.1\|726469_727729_+\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NZ_LS483357.1\|WP_002984095.1\|728977_729520_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.44756e-30

>NZ_LS483357.1|WP_011528739.1|726469_727729_+|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLLTNGQKIHGAHIYMDTISVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
>NZ_LS483357.1|WP_011528740.1|725099_726296_+|methionine-adenosyltransferase
MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSGDIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLAELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKVIKDVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPEAVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVEAVKTVL
>NZ_LS483357.1|WP_111678880.1|722250_724563_+|pneumococcal-type-histidine-triad-protein
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSLFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGYTIRHDDHFHYILKSSLSGQTQAQAKQVATRLAQTSSPVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKMKDWLATVIKLDLGSRKDPLQCKGLSLLPNLETLGLGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSNLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAVATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
>NZ_LS483357.1|WP_021299177.1|721106_722048_-|bifunctional-biotin--[acetyl-CoA-carboxylase]-synthetase/biotin-operon-repressor
MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQGIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPRLYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYTDMPPYTMMVASSIVKAISRLTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIAQKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEKRAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN
>NZ_LS483357.1|WP_136280421.1|720928_721132_+|DUF3272-domain-containing-protein
MTIRQFLFMVFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLRRVHTINQLTKTILKTANSPKKKD
>NZ_LS483357.1|WP_021299185.1|719163_720834_+|DNA-polymerase-III-subunit-gamma/tau
MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSGPRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDEIRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHKIPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALSILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGKSMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIKKGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPDSLARSDKTKSKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQDRALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVPRTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD
>NZ_LS483357.1|WP_011017927.1|718666_719164_+|GAF-domain-containing-protein
MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPNSVFTGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYISCDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLETFVDLLLEKTTFTFNMFGVKN
>NZ_LS483357.1|WP_002989260.1|717712_718522_-|PrsW-family-intramembrane-metalloprotease
MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALILTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWSYIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQLTEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQIFWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF
>NZ_LS483357.1|WP_002989257.1|717396_717660_+|DUF1294-domain-containing-protein
MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITVLFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK
>NZ_LS483357.1|WP_002984060.1|716690_717317_+|uridine-kinase
MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYKDQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQDPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV
>NZ_LS483357.1|WP_002984095.1|728977_729520_+|GNAT-family-N-acetyltransferase
MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYVFPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFLNYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKGSDRNTHKICIYKMYQLTNDR
>NZ_LS483357.1|WP_044555083.1|729528_730812_+|CBS-domain-containing-protein
MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAENRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGAMTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPVMVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKKTRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMIFEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVVVEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMIYFLHAIQIEDELKIYPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN
>NZ_LS483357.1|WP_002984100.1|730827_731688_+|methionyl-aminopeptidase
MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYVRRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLSEPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEAMYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVILTSQGEERTY
>NZ_LS483357.1|WP_011528735.1|731689_732655_+|YihY/virulence-factor-BrkB-family-protein
MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLILTAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVATLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTFSKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILPGTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIFNATYQEMSLGKLEGRSGDMIAILKKTLGNDSGLSPSQSIEDSHTD
>NZ_LS483357.1|WP_011528734.1|732765_734049_+|3-phosphoshikimate-1-carboxyvinyltransferase
MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNHNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSRLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD
>NZ_LS483357.1|WP_002984106.1|734041_734533_+|shikimate-kinase
MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFTNDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
>NZ_LS483357.1|WP_011528733.1|734740_736192_+|LCP-family-protein
MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEIGRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKEDRYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIFGLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVTQGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGEQEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVAVDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVMSAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPENGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR
>NZ_LS483357.1|WP_011528732.1|736240_737632_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHGGFVFFVDNALPEEVIDMRVLKVNKNSGFGKVEVYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAISAQSFYQVNTIMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEVIEAAVRDAQQNAALNGITNAYFIADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLTKVQPVDLFPQTHHVECVSLLEKRS
>NZ_LS483357.1|WP_011528730.1|738646_739048_+|PaaI-family-thioesterase
MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYGDAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTTQVVDVTIHNQTGALLTKTSLTMFVTGRRHNG
>NZ_LS483357.1|WP_011888813.1|739152_740637_-|DUF1846-domain-containing-protein
MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	NZ_LS483357.1	630720-630752	1	0.97

1. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to position: 630720-630752, mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448771	Streptococcus phage Javan481, complete genome	8314-8348	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK449010	Streptococcus phage Javan90, complete genome	10748-10782	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK449012	Streptococcus phage Javan94, complete genome	9759-9793	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448972	Streptococcus phage Javan520, complete genome	8239-8273	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448763	Streptococcus phage Javan451, complete genome	9432-9466	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448845	Streptococcus phage Javan118, complete genome	10042-10076	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448833	Streptococcus phage Javan87, complete genome	10748-10782	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448762	Streptococcus phage Javan447, complete genome	55-88	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448798	Streptococcus phage Javan533, complete genome	55-88	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448793	Streptococcus phage Javan523, complete genome	55-88	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448967	Streptococcus phage Javan510, complete genome	55-88	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	MK448954	Streptococcus phage Javan476, complete genome	55-88	0	1.0
NZ_LS483357_1	1.4\|562805\|34\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562805-562838	34	NC_004588	Streptococcus prophage 315.5, complete genome	204-237	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448771	Streptococcus phage Javan481, complete genome	6934-6966	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448681	Streptococcus phage Javan141, complete genome	6532-6564	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448944	Streptococcus phage Javan452, complete genome	11198-11230	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448672	Streptococcus phage Javan117, complete genome	6780-6812	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448849	Streptococcus phage Javan128, complete genome	6683-6715	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448774	Streptococcus phage Javan487, complete genome	6919-6951	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448958	Streptococcus phage Javan486, complete genome	9163-9195	0	1.0
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448742	Streptococcus phage Javan37, complete genome	9155-9187	0	1.0
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448862	Streptococcus phage Javan178, complete genome	8290-8324	1	0.971
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448681	Streptococcus phage Javan141, complete genome	8090-8124	1	0.971
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448672	Streptococcus phage Javan117, complete genome	8159-8193	1	0.971
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448849	Streptococcus phage Javan128, complete genome	8063-8097	1	0.971
NZ_LS483357_1	1.3\|562738\|35\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562738-562772	35	MK448850	Streptococcus phage Javan132, complete genome	12888-12922	1	0.971
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448767	Streptococcus phage Javan467, complete genome	6872-6904	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448973	Streptococcus phage Javan522, complete genome	8839-8871	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448862	Streptococcus phage Javan178, complete genome	6908-6940	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448942	Streptococcus phage Javan448, complete genome	6871-6903	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK449010	Streptococcus phage Javan90, complete genome	9367-9399	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK449012	Streptococcus phage Javan94, complete genome	8201-8233	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	NC_004586	Streptococcus pyogenes phage 315.3, complete genome	6977-7009	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448969	Streptococcus phage Javan514, complete genome	9627-9659	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448943	Streptococcus phage Javan450, complete genome	6872-6904	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448972	Streptococcus phage Javan520, complete genome	6681-6713	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448786	Streptococcus phage Javan509, complete genome	6872-6904	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448778	Streptococcus phage Javan493, complete genome	8854-8886	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448963	Streptococcus phage Javan498, complete genome	3461-3493	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448773	Streptococcus phage Javan485, complete genome	9627-9659	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448851	Streptococcus phage Javan14, complete genome	12140-12172	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448833	Streptococcus phage Javan87, complete genome	9367-9399	1	0.97
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448673	Streptococcus phage Javan119, complete genome	9946-9978	1	0.97
NZ_LS483357_1	1.2\|562673\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562673-562705	33	MK448955	Streptococcus phage Javan478, complete genome	13965-13997	2	0.939
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448964	Streptococcus phage Javan502, complete genome	6851-6883	2	0.939
NZ_LS483357_1	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	MK448845	Streptococcus phage Javan118, complete genome	8661-8693	5	0.848

1. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

2. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

3. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

4. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

5. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

6. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

7. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 0, identity: 1.0

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaataccgattttaagc	Protospacer
***********************************

8. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

9. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

10. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

11. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

12. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

13. spacer 1.4|562805|34|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 0, identity: 1.0

aaataattacatgactagccaatacacccacata	CRISPR spacer
aaataattacatgactagccaatacacccacata	Protospacer
**********************************

14. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448771 (Streptococcus phage Javan481, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

15. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

16. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

17. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

18. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

19. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448774 (Streptococcus phage Javan487, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

20. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

21. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448742 (Streptococcus phage Javan37, complete genome) position: , mismatch: 0, identity: 1.0

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttctttactctcaaagtaagagtg	Protospacer
*********************************

22. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagttacaatgccgattttaagc	Protospacer
**********************.************

23. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

24. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

25. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgataccagtaacaataccgattttaagc	Protospacer
**************** ******************

26. spacer 1.3|562738|35|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448850 (Streptococcus phage Javan132, complete genome) position: , mismatch: 1, identity: 0.971

ctaagatgataccagttacaataccgattttaagc	CRISPR spacer
ctaagatgatgccagttacaataccgattttaagc	Protospacer
**********.************************

27. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448767 (Streptococcus phage Javan467, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

28. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

29. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

30. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448942 (Streptococcus phage Javan448, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

31. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

32. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

33. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to NC_004586 (Streptococcus pyogenes phage 315.3, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

34. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448969 (Streptococcus phage Javan514, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

35. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448943 (Streptococcus phage Javan450, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

36. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448972 (Streptococcus phage Javan520, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

37. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448786 (Streptococcus phage Javan509, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

38. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

39. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448963 (Streptococcus phage Javan498, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

40. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448773 (Streptococcus phage Javan485, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

41. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

42. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

43. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 1, identity: 0.97

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagctgctttactctcaaagtaagagtg	Protospacer
********** **********************

44. spacer 1.2|562673|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 2, identity: 0.939

atttcgtcacctcctcaatcaataatagagtca	CRISPR spacer
atttcgtcaactcctcaataaataatagagtca	Protospacer
********* ********* *************

45. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448964 (Streptococcus phage Javan502, complete genome) position: , mismatch: 2, identity: 0.939

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttaccctcaaagtaagagtg	Protospacer
***********.*****.***************

46. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 5, identity: 0.848

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ggaataagctgctttactctcaaagtaagagtg	Protospacer
   **.**** **********************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

605451 : 662798

Streptococcus_phage(62.5%)

holin,protease,portal,capsid,integrase,terminase,tail

attL 623744:623763|attR 659340:659359

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011528807.1\|605451_607734_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	8.3e-125	39.6
WP_002983885.1\|608030_608261_+	YkuJ family protein	NA	NA	NA	NA
WP_002983887.1\|608387_609074_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_002983889.1\|609073_609808_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.3e-34	38.4
WP_111678879.1\|609955_611365_+	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	2.0e-60	32.8
WP_021299343.1\|611542_613237_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.0e-128	42.4
WP_002989114.1\|613444_614299_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	4.4e-39	39.4
WP_002992349.1\|614451_615792_+	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	8.2e-40	30.9
WP_002983901.1\|615769_615985_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_011284950.1\|615984_616857_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_009880629.1\|616849_617677_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_002983907.1\|617663_618134_+	arginine repressor	NA	NA	NA	NA
WP_002983909.1\|618154_619816_+	DNA repair protein RecN	NA	NA	NA	NA
WP_011528800.1\|619987_620920_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002983913.1\|621135_621987_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_002992620.1\|621979_622822_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|622799_623387_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|623485_623761_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
623744:623763	attL	NA	NA	NA	NA
WP_003051793.1\|623849_624992_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_011528799.1\|625115_625634_-	restriction endonuclease	E8ZDN5	Streptococcus_phage	1.6e-31	45.9
WP_010922480.1\|625645_626401_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.8e-77	60.8
WP_010922479.1\|626602_626815_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	1.1e-10	56.7
WP_010922478.1\|627084_627396_+	excisionase	A0A1S5SA25	Streptococcus_phage	5.3e-43	77.7
WP_010922477.1\|627397_627583_+	hypothetical protein	Q938N3	Temperate_phage	1.3e-20	83.6
WP_011017564.1\|628086_628473_+	DnaD domain-containing protein	Q938N2	Temperate_phage	8.1e-25	51.9
WP_010922205.1\|628453_628687_+	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_002988354.1\|628683_628824_+	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	3.4e-05	54.5
WP_002988357.1\|628832_629039_+	hypothetical protein	NA	NA	NA	NA
WP_011528796.1\|629094_629424_+	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_011054700.1\|629426_630353_+	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_000594115.1\|630349_630550_+	hypothetical protein	NA	NA	NA	NA
WP_011054699.1\|630542_631340_+	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	1.3e-130	83.8
WP_011054698.1\|631704_632100_+	hypothetical protein	A8ATL9	Listeria_phage	1.4e-19	52.3
WP_011054697.1\|632096_633443_+	PcfJ domain-containing protein	A8ATM0	Listeria_phage	1.0e-122	49.4
WP_011184741.1\|633453_633786_+	hypothetical protein	M1NS23	Streptococcus_phage	8.8e-36	67.0
WP_011054695.1\|633782_634295_+	hypothetical protein	M1PFM2	Streptococcus_phage	1.7e-78	85.9
WP_011054694.1\|634330_634648_+	DUF1372 family protein	A1EAD7	Streptococcus_phage	9.0e-30	71.4
WP_011054693.1\|634644_634800_+	hypothetical protein	NA	NA	NA	NA
WP_011054692.1\|634796_635048_+	hypothetical protein	M1PF60	Streptococcus_phage	1.6e-18	59.0
WP_011528791.1\|635123_635543_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	6.7e-57	79.9
WP_011054690.1\|635650_635995_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
WP_002994106.1\|636142_636499_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_010922468.1\|636495_637764_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	2.2e-188	75.6
WP_010922467.1\|637756_639250_+	hypothetical protein	M1Q184	Streptococcus_phage	2.0e-87	55.0
WP_002994100.1\|639255_639480_+	hypothetical protein	NA	NA	NA	NA
WP_011054745.1\|639531_639798_+	hypothetical protein	Q938K9	Temperate_phage	1.5e-38	100.0
WP_021299324.1\|640117_641533_+\|terminase	phage terminase large subunit-like protein	A0A0B5A091	Streptococcus_phage	2.0e-214	74.6
WP_010922462.1\|641612_642074_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	4.5e-38	53.2
WP_011528788.1\|642098_643010_+\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	2.2e-113	67.0
WP_010922460.1\|643009_643210_+	hypothetical protein	NA	NA	NA	NA
WP_011054682.1\|643219_643642_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_011054681.1\|643601_643940_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_000032787.1\|643932_644169_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_011528787.1\|644169_644505_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	1.7e-34	64.9
WP_014635577.1\|644516_645095_+	hypothetical protein	A0A1X9I5X2	Streptococcus_phage	2.9e-58	62.9
WP_003047548.1\|645105_645369_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.7e-18	54.7
WP_011528785.1\|645383_645755_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
WP_011528784.1\|645754_648112_+	hypothetical protein	M1NRG5	Streptococcus_phage	2.6e-134	50.3
WP_002992579.1\|648108_648804_+	hypothetical protein	A0A1B1P761	Bacillus_phage	4.7e-07	32.2
WP_011528783.1\|648785_650762_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	1.4e-99	49.9
WP_011528782.1\|650758_651874_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	4.8e-110	66.6
WP_011528780.1\|653677_654106_+	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	87.9
WP_011528779.1\|654108_654741_+	hypothetical protein	Q938J7	Temperate_phage	4.0e-45	50.5
WP_011017397.1\|654752_655025_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_003058873.1\|655021_655249_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_011528778.1\|655367_656585_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	1.4e-163	60.1
WP_002988467.1\|656720_657845_+	Fic family protein	D7RWK9	Brochothrix_phage	3.1e-93	49.1
WP_002988472.1\|658092_658875_+	exotoxin	A0A097PAT7	Streptococcus_pyogenes_phage	4.3e-49	45.8
WP_011528776.1\|658987_659170_+	hypothetical protein	A3F673	Streptococcus_phage	5.3e-19	75.0
WP_011528775.1\|659700_661563_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	7.0e-90	33.8
659340:659359	attR	NA	NA	NA	NA
WP_002989134.1\|661634_661808_+	hypothetical protein	NA	NA	NA	NA
WP_021299339.1\|661862_662798_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	4.6e-66	45.1

DBSCAN-SWA_2

1038280 : 1078715

Streptococcus_pyogenes_phage(50.94%)

holin,portal,capsid,integrase,terminase,tail

attL 1038068:1038113|attR 1075943:1075988

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1038068:1038113	attL	NA	NA	NA	NA
WP_011528571.1\|1038280_1038469_-	hypothetical protein	A3F673	Streptococcus_phage	6.1e-18	73.3
WP_011285611.1\|1038706_1039507_+	streptodornase Sda3	NA	NA	NA	NA
WP_011017966.1\|1039778_1040213_+	hypothetical protein	NA	NA	NA	NA
WP_011528570.1\|1040281_1040941_-	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	6.3e-118	96.3
WP_009880241.1\|1040940_1041162_-	hypothetical protein	A0A097PAX7	Streptococcus_pyogenes_phage	2.5e-18	84.5
WP_011528569.1\|1041171_1041945_-	hypothetical protein	A0A097PAV0	Streptococcus_pyogenes_phage	4.6e-128	94.6
WP_011054796.1\|1041955_1042558_-	hypothetical protein	A0A097PAX9	Streptococcus_pyogenes_phage	7.8e-91	98.8
WP_011054797.1\|1042569_1043334_-	CHAP domain-containing protein	A0A097PAT3	Streptococcus_pyogenes_phage	1.5e-150	100.0
WP_011054798.1\|1043335_1043668_-\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	5.7e-51	100.0
WP_015055952.1\|1043667_1043991_-	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	7.7e-53	100.0
WP_009880247.1\|1044140_1044488_-	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	3.5e-59	100.0
WP_011528568.1\|1044498_1046361_-	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	0.0e+00	99.8
WP_050336170.1\|1046365_1049815_-\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	99.0
WP_011528566.1\|1049815_1051300_-\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	1.8e-290	98.8
WP_111678884.1\|1051300_1053106_-\|tail	phage tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	1.4e-249	94.8
WP_011528564.1\|1053098_1053557_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	7.0e-76	93.4
WP_011528563.1\|1053529_1053847_-	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	1.9e-51	98.1
WP_079890482.1\|1053859_1054366_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	8.3e-78	98.7
WP_011528561.1\|1054377_1054788_-	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	1.8e-70	99.3
WP_011528560.1\|1054789_1055185_-	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	1.8e-56	93.0
WP_011528559.1\|1055181_1055493_-	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	4.6e-47	94.2
WP_011528558.1\|1055489_1055834_-	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	1.5e-54	99.1
WP_011528557.1\|1055847_1056141_-	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	1.3e-46	99.0
WP_011528556.1\|1056152_1057043_-	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	8.6e-86	99.4
WP_021299309.1\|1057061_1057631_-	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	1.4e-60	90.5
WP_011528554.1\|1057742_1057973_-	hypothetical protein	Q938K9	Temperate_phage	4.0e-19	62.5
WP_011528553.1\|1057979_1058888_-\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	2.4e-83	94.5
WP_011528552.1\|1058856_1060182_-\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	6.3e-234	95.6
WP_021299302.1\|1060181_1061456_-\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	1.9e-251	99.8
WP_011285571.1\|1061445_1061826_-	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	1.0e-64	100.0
WP_011528550.1\|1061912_1062131_+	hypothetical protein	NA	NA	NA	NA
WP_011017866.1\|1062494_1062935_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_164997036.1\|1063208_1063379_-	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	1.1e-26	98.2
WP_011054751.1\|1063375_1063882_-	DUF1642 domain-containing protein	Q938L9	Temperate_phage	9.8e-95	100.0
WP_011054752.1\|1063878_1064049_-	hypothetical protein	Q938M0	Temperate_phage	4.2e-26	100.0
WP_011054753.1\|1064045_1064450_-	hypothetical protein	Q938M1	Temperate_phage	6.0e-71	100.0
WP_002987593.1\|1064459_1064729_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011017568.1\|1064725_1065010_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_011018138.1\|1065251_1065608_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_002995960.1\|1065591_1065912_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	2.0e-53	100.0
WP_011528547.1\|1067626_1068439_-	bifunctional DNA primase/polymerase	A0A1P8VVM6	Streptococcus_phage	7.2e-156	99.3
WP_002995969.1\|1068441_1068900_-	DUF669 domain-containing protein	A0A1P8VVN0	Streptococcus_phage	3.8e-82	100.0
WP_011528546.1\|1068915_1070145_-	DEAD/DEAH box helicase	A0A1P8VVM2	Streptococcus_phage	3.3e-237	100.0
WP_002995975.1\|1070246_1070927_-	AAA family ATPase	A0A1P8VVS4	Streptococcus_phage	1.6e-129	100.0
WP_011528545.1\|1070927_1071410_-	siphovirus Gp157 family protein	A0A1P8VVS5	Streptococcus_phage	1.2e-78	100.0
WP_011528544.1\|1071636_1071951_-	helix-turn-helix transcriptional regulator	A0A1P8VVN6	Streptococcus_phage	1.7e-52	100.0
WP_011528542.1\|1072131_1072383_-	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.8e-42	100.0
WP_009881062.1\|1072477_1072696_-	helix-turn-helix transcriptional regulator	A0A1P8VVR5	Streptococcus_phage	4.1e-34	100.0
WP_011528540.1\|1072884_1073244_+	helix-turn-helix transcriptional regulator	A0A1P8VVN3	Streptococcus_phage	1.8e-58	98.3
WP_011054824.1\|1073227_1073605_+	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	4.0e-69	100.0
WP_172451528.1\|1073615_1073768_+	hypothetical protein	A0A1P8VVQ0	Streptococcus_phage	1.5e-19	98.0
WP_011528539.1\|1073938_1074625_+	hypothetical protein	A0A1P8VVT3	Streptococcus_phage	5.7e-122	100.0
WP_011528538.1\|1074746_1075886_+\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	4.4e-119	55.8
WP_002984881.1\|1075968_1077009_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.1e-68	43.9
1075943:1075988	attR	NA	NA	NA	NA
WP_002990099.1\|1077252_1077846_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
WP_002992970.1\|1077845_1078715_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.4e-101	64.6

DBSCAN-SWA_3

1185115 : 1195719

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021299166.1\|1185115_1186258_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.1e-24	27.3
WP_021299165.1\|1186492_1186933_+	hypothetical protein	NA	NA	NA	NA
WP_111678887.1\|1186962_1188231_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_011284677.1\|1188318_1189671_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
WP_011528484.1\|1189892_1190234_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	41.1
WP_002990262.1\|1190294_1191461_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_002985140.1\|1191554_1192241_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_002985142.1\|1192237_1193401_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	3.4e-143	65.1
WP_011054348.1\|1193508_1195719_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.1

DBSCAN-SWA_4

1232451 : 1338174

111

Streptococcus_phage(57.75%)

holin,head,transposase,protease,portal,capsid,tRNA,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021299203.1\|1232451_1234857_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_011528461.1\|1235066_1236110_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	4.6e-30	34.3
WP_002985226.1\|1237292_1237481_-	DNA-directed RNA polymerase subunit beta	NA	NA	NA	NA
WP_002990414.1\|1237484_1238756_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002994426.1\|1238820_1239078_-	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_002985233.1\|1239343_1239760_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_011017611.1\|1239772_1241179_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_002985236.1\|1241340_1242216_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_002985238.1\|1242231_1243740_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_111678888.1\|1243755_1244292_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_002990420.1\|1244291_1244786_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_002985244.1\|1244803_1245520_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_002985249.1\|1245554_1245752_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_011528458.1\|1246159_1247182_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	6.1e-19	27.9
WP_011528457.1\|1247195_1249154_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	5.8e-103	34.9
WP_002985256.1\|1249346_1249847_-	QueT transporter family protein	E7DN70	Pneumococcus_phage	5.4e-05	31.8
WP_011528456.1\|1250124_1252857_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_011528455.1\|1253428_1254547_-	ABC transporter permease	NA	NA	NA	NA
WP_002985266.1\|1254543_1255671_-	ABC transporter permease	NA	NA	NA	NA
WP_002990429.1\|1255679_1256603_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-33	38.1
WP_011528454.1\|1256625_1257309_-	hypothetical protein	NA	NA	NA	NA
WP_111678889.1\|1257305_1257977_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002990434.1\|1257951_1259310_-	YcaO-like family protein	NA	NA	NA	NA
WP_011528452.1\|1259329_1260388_-	streptolysin associated protein SagC	NA	NA	NA	NA
WP_010922108.1\|1260384_1261335_-	streptolysin S biosynthesis dehydrogenase SagB	NA	NA	NA	NA
WP_002985285.1\|1261556_1261718_-	TOMM family cytolysin streptolysin S	NA	NA	NA	NA
WP_160399535.1\|1262582_1266947_-	DUF1542 domain-containing protein	NA	NA	NA	NA
WP_042769776.1\|1267419_1268961_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002985288.1\|1270732_1272040_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
WP_002990451.1\|1272266_1272725_+	YueI family protein	W6LLD2	Streptococcus_phage	1.8e-18	39.1
WP_011528447.1\|1272856_1274581_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_011528446.1\|1274948_1276901_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	6.8e-144	46.3
WP_002985295.1\|1276901_1277471_-	hydrolase	NA	NA	NA	NA
WP_002985298.1\|1278498_1278846_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_111678890.1\|1278960_1280223_-	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	1.9e-94	50.8
WP_011528443.1\|1280215_1280500_-	chorismate mutase	NA	NA	NA	NA
WP_002985303.1\|1280675_1281125_-	flavodoxin	NA	NA	NA	NA
WP_011528442.1\|1281518_1282460_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985307.1\|1282574_1282835_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_011528441.1\|1282932_1284132_-	SIS domain-containing protein	NA	NA	NA	NA
WP_021299176.1\|1284151_1284874_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_111678891.1\|1285116_1286580_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	2.2e-256	92.1
WP_011528437.1\|1286596_1288144_-	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_011528436.1\|1288295_1289714_-	C69 family dipeptidase	NA	NA	NA	NA
WP_002985324.1\|1290025_1290784_+	DNase Mf2	NA	NA	NA	NA
WP_002985327.1\|1290894_1291602_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_002985329.1\|1291669_1292875_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.6e-204	83.3
WP_000609113.1\|1292990_1293218_-\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_002987582.1\|1293214_1293490_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_011017592.1\|1293499_1294117_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	5.0e-77	89.3
WP_002983467.1\|1294119_1294551_-	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011527561.1\|1294562_1296449_-	gp58-like family protein	Q938J9	Temperate_phage	3.1e-218	84.7
WP_011017589.1\|1296461_1297472_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	7.8e-136	75.8
WP_011527560.1\|1297468_1299613_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	94.7
WP_011527559.1\|1299609_1300317_-\|tail	phage tail family protein	Q938K2	Temperate_phage	6.8e-94	71.9
WP_002985338.1\|1300316_1304240_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.9e-238	48.5
WP_021299462.1\|1304252_1304402_-	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_011017586.1\|1304449_1304776_-	hypothetical protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
WP_011017585.1\|1304828_1305437_-	hypothetical protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
WP_011017584.1\|1305452_1305878_-	hypothetical protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
WP_011527557.1\|1305874_1306252_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
WP_011017582.1\|1306248_1306596_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
WP_011017581.1\|1306592_1306895_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
WP_011017580.1\|1307039_1308227_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
WP_011017579.1\|1308251_1308917_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	3.5e-92	78.1
WP_011017578.1\|1308894_1310115_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_002985363.1\|1310148_1310373_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1310365_1310536_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_024623442.1\|1310532_1312287_-	amino acid transporter	J7KKD1	Streptococcus_phage	0.0e+00	96.1
WP_002985368.1\|1312290_1312521_-	hypothetical protein	NA	NA	NA	NA
WP_002985371.1\|1312523_1312991_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_002985375.1\|1313161_1313500_-	HNH endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
WP_001132273.1\|1313735_1313921_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1313972_1314350_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_011017575.1\|1314476_1315406_-	DNA adenine methylase	A0A126HAU2	Lactococcus_phage	4.9e-100	71.8
WP_011017574.1\|1315988_1316426_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	6.7e-76	97.9
WP_002987493.1\|1316701_1316872_-	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_011017573.1\|1316868_1317594_-	DUF1642 domain-containing protein	Q938L9	Temperate_phage	3.1e-25	44.8
WP_021299463.1\|1317641_1318406_-	site-specific DNA-methyltransferase	A0A1S5SE41	Streptococcus_phage	4.2e-134	92.3
WP_011017571.1\|1318395_1318878_-	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_011017570.1\|1318881_1319166_-	hypothetical protein	A3F628	Streptococcus_phage	4.6e-33	79.8
WP_011017569.1\|1319162_1319576_-	hypothetical protein	Q938M1	Temperate_phage	6.4e-36	65.2
WP_002987593.1\|1319585_1319855_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011527551.1\|1319851_1320037_-	hypothetical protein	A3F626	Streptococcus_phage	1.7e-12	94.7
WP_011527550.1\|1320029_1320311_-	DUF1599 domain-containing protein	J7KDH9	Streptococcus_phage	2.5e-31	75.0
WP_011527549.1\|1320435_1320792_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	7.7e-54	87.3
WP_011527548.1\|1320775_1321096_-	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	1.9e-51	95.3
WP_011527547.1\|1321092_1321506_-	hypothetical protein	A0A2H4JHE6	uncultured_Caudovirales_phage	1.6e-15	51.1
WP_011527546.1\|1321767_1323243_-	DNA primase	A0A1P8VVM0	Streptococcus_phage	2.4e-242	84.2
WP_011527545.1\|1323232_1324045_-	bifunctional DNA primase/polymerase	J7KH42	Streptococcus_phage	1.9e-153	97.4
WP_011527544.1\|1324047_1324506_-	DUF669 domain-containing protein	A0A1P8VVN0	Streptococcus_phage	2.2e-77	94.1
WP_011527543.1\|1324521_1325757_-	DEAD/DEAH box helicase	J7KK96	Streptococcus_phage	3.3e-229	95.4
WP_011527542.1\|1325852_1326545_-	AAA family ATPase	J7KC09	Streptococcus_phage	5.9e-127	96.1
WP_011527541.1\|1326531_1326843_-	hypothetical protein	A0A1S5PRW6	Streptococcus_phage	8.0e-23	48.5
WP_008087492.1\|1326952_1327135_-	hypothetical protein	A0A2P0ZLA4	Lactobacillus_phage	4.0e-06	43.8
WP_011527540.1\|1327122_1327335_-	hypothetical protein	NA	NA	NA	NA
WP_011527539.1\|1327344_1327485_-	hypothetical protein	A0A1P8VVR9	Streptococcus_phage	4.2e-16	91.1
WP_011527538.1\|1327481_1327727_-	hypothetical protein	NA	NA	NA	NA
WP_008087494.1\|1327799_1327985_-	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	3.5e-18	68.9
WP_011527536.1\|1328129_1328360_+	hypothetical protein	NA	NA	NA	NA
WP_002984292.1\|1328522_1328732_+	hypothetical protein	NA	NA	NA	NA
WP_001157159.1\|1328977_1329184_-	helix-turn-helix domain-containing protein	A0A1X9I5S3	Streptococcus_phage	1.1e-17	64.7
WP_001008979.1\|1329276_1329918_+	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_002985414.1\|1330016_1330175_-	hypothetical protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
WP_011527535.1\|1330561_1331311_+	helix-turn-helix domain-containing protein	A0A097PBE5	Streptococcus_pyogenes_phage	4.5e-80	63.8
WP_021299479.1\|1331336_1331879_+	PH domain-containing protein	Q4ZA70	Staphylococcus_virus	3.9e-33	41.9
WP_011017563.1\|1332029_1333445_+	recombinase family protein	A5GZ62	Lactococcus_phage	1.4e-109	47.2
WP_002990485.1\|1333641_1334553_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.9e-105	64.4
WP_011017561.1\|1334549_1335527_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-138	74.2
WP_002985434.1\|1335523_1336414_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_011528431.1\|1336827_1338174_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.4e-55	30.8

DBSCAN-SWA_5

1447931 : 1545758

Streptococcus_phage(21.43%)

bacteriocin,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011528363.1\|1447931_1449875_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	8.0e-121	38.7
WP_011528362.1\|1450296_1451631_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002985678.1\|1451632_1452631_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_002985680.1\|1452761_1453763_-	catabolite control protein A	C6ZCU4	Enterobacteria_phage	6.1e-24	28.5
WP_011528361.1\|1453936_1455022_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_002985684.1\|1455070_1455736_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_002985686.1\|1455746_1456124_+	VOC family protein	NA	NA	NA	NA
WP_002990711.1\|1456268_1457195_+	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	1.5e-77	47.5
WP_011017476.1\|1457405_1458089_+	DUF969 domain-containing protein	NA	NA	NA	NA
WP_011528360.1\|1458088_1459015_+	DUF979 family protein	NA	NA	NA	NA
WP_011017474.1\|1459064_1459712_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_011528359.1\|1459826_1460537_-	glutaminyl-peptide cyclotransferase	NA	NA	NA	NA
WP_011528358.1\|1460551_1461019_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	7.5e-41	57.0
WP_011528357.1\|1461021_1463355_-	ribonuclease R	Q0GXV6	Lactococcus_phage	3.0e-90	39.6
WP_002985700.1\|1463448_1463685_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_002990729.1\|1463730_1463877_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_011528356.1\|1463873_1465067_-	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_011017470.1\|1465188_1466691_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	3.9e-75	41.6
WP_011017469.1\|1466880_1467474_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_011528354.1\|1467470_1468298_-	DNA-formamidopyrimidine glycosylase	A0A127AWE5	Bacillus_phage	3.9e-16	27.5
WP_021299215.1\|1468469_1469336_-	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_128650799.1\|1469424_1469493_+	peptide pheromone SHP2	NA	NA	NA	NA
WP_011017467.1\|1470406_1470676_+	quorum-sensing system protein StcA	NA	NA	NA	NA
WP_011528352.1\|1471023_1471422_-	hypothetical protein	NA	NA	NA	NA
WP_042769789.1\|1471514_1472585_-	hypothetical protein	NA	NA	NA	NA
WP_002985720.1\|1472826_1473237_-	hypothetical protein	NA	NA	NA	NA
WP_011528350.1\|1473430_1473712_-	hypothetical protein	NA	NA	NA	NA
WP_011528349.1\|1474250_1474448_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|1474460_1474688_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|1475879_1476062_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_021299285.1\|1476076_1476322_-\|bacteriocin	bacteriocin class II with double-glycine leader peptide	NA	NA	NA	NA
WP_011528347.1\|1477649_1479803_+	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	4.4e-43	28.5
WP_011017462.1\|1481254_1481380_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_111678896.1\|1481527_1482862_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_011528343.1\|1482862_1483612_-	response regulator transcription factor	A0A1V0E029	Clostridioides_phage	9.6e-22	28.0
WP_111678914.1\|1483989_1484088_-	hypothetical protein	NA	NA	NA	NA
WP_011528341.1\|1484517_1484814_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.5e-06	42.0
WP_011528340.1\|1484846_1485128_-\|transposase	transposase	NA	NA	NA	NA
WP_021299375.1\|1485193_1485511_-	hypothetical protein	NA	NA	NA	NA
WP_042769846.1\|1485559_1485787_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_157261042.1\|1486397_1486646_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002994581.1\|1487002_1487179_-	hypothetical protein	NA	NA	NA	NA
WP_002994580.1\|1487156_1487381_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_002994577.1\|1487678_1487915_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_011528336.1\|1488019_1488730_+\|bacteriocin	bacteriocin ABC transporter	NA	NA	NA	NA
WP_011528335.1\|1488952_1489399_+	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	2.0e-11	35.1
WP_014635332.1\|1490559_1491036_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_003047080.1\|1491055_1491952_-	GTPase Era	NA	NA	NA	NA
WP_002985746.1\|1492071_1492479_-	diacylglycerol kinase	NA	NA	NA	NA
WP_002985748.1\|1492459_1492957_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_009880369.1\|1493115_1493691_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_010921967.1\|1493736_1494789_-	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_042769843.1\|1494947_1496720_-	oleate hydratase	NA	NA	NA	NA
WP_011528331.1\|1497035_1498217_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.6e-16	40.5
WP_002985757.1\|1498372_1498588_-	YozE family protein	NA	NA	NA	NA
WP_002985759.1\|1498584_1499094_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_011528329.1\|1499166_1500024_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985763.1\|1500132_1500690_-	ribosome recycling factor	NA	NA	NA	NA
WP_002985765.1\|1500718_1501447_-	UMP kinase	NA	NA	NA	NA
WP_002985768.1\|1501768_1502458_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002990800.1\|1502563_1502989_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_010921962.1\|1503232_1503586_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_011528327.1\|1503655_1506061_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_002990808.1\|1506277_1507084_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_011017448.1\|1507231_1508086_-	metal ABC transporter permease	NA	NA	NA	NA
WP_021299377.1\|1508086_1508812_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.1e-17	32.6
WP_004218965.1\|1508875_1509808_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002985785.1\|1509953_1510601_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_011528324.1\|1510697_1511039_-	hypothetical protein	NA	NA	NA	NA
WP_011528323.1\|1511189_1511885_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002990826.1\|1511904_1512156_-	hypothetical protein	NA	NA	NA	NA
WP_002990829.1\|1512155_1512710_-	NUDIX hydrolase	NA	NA	NA	NA
WP_021299380.1\|1512740_1514123_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	1.3e-32	36.4
WP_002985796.1\|1514295_1515633_-	MFS transporter	NA	NA	NA	NA
WP_044555074.1\|1515965_1516925_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011528320.1\|1517000_1517699_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	2.3e-09	24.4
WP_002990844.1\|1517691_1517928_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_011528316.1\|1520108_1520816_+	hypothetical protein	NA	NA	NA	NA
WP_011017435.1\|1520909_1521161_-	hypothetical protein	NA	NA	NA	NA
WP_136278216.1\|1521393_1521759_-	hypothetical protein	NA	NA	NA	NA
WP_044555125.1\|1522068_1522563_-	hypothetical protein	NA	NA	NA	NA
WP_021299376.1\|1523021_1523774_+	ADP-ribosyltransferase	NA	NA	NA	NA
WP_011528311.1\|1523979_1526160_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.6e-170	43.1
WP_011528310.1\|1526179_1526614_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.2e-11	37.5
WP_011528309.1\|1526617_1527631_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	1.9e-97	53.7
WP_011528307.1\|1528125_1530126_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	3.5e-87	35.3
WP_011528304.1\|1531621_1532329_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_060388498.1\|1533100_1538044_-\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_044555073.1\|1538309_1539491_-	L-lactate oxidase	NA	NA	NA	NA
WP_021299194.1\|1539724_1540552_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.2e-128	79.5
WP_002995120.1\|1540625_1540982_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	2.8e-40	66.7
WP_011528296.1\|1541281_1541911_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002985833.1\|1541957_1542350_-	hypothetical protein	NA	NA	NA	NA
WP_002990904.1\|1542376_1543240_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.5e-114	74.7
WP_002985838.1\|1543244_1543568_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_021299187.1\|1543971_1544211_-	PSP1 C-terminal domain protein	NA	NA	NA	NA
WP_011528291.1\|1544229_1545105_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.8e-72	47.9
WP_021299190.1\|1545122_1545758_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.0e-65	63.4

DBSCAN-SWA_6

1813343 : 1835861

Streptococcus_phage(47.06%)

holin,tRNA,integrase

attL 1816542:1816562|attR 1830407:1830427

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011529098.1\|1813343_1814564_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.6e-05	23.3
WP_021299132.1\|1814574_1816557_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
1816542:1816562	attL	NA	NA	NA	NA
WP_021299091.1\|1816651_1817797_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	2.7e-84	44.9
WP_011185066.1\|1817999_1818143_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_011529101.1\|1819040_1819688_-	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	4.4e-15	28.1
WP_011529102.1\|1819853_1820051_+	helix-turn-helix transcriptional regulator	A0A1X9I5U5	Streptococcus_phage	3.7e-18	72.3
WP_021299093.1\|1820064_1820679_+	hypothetical protein	A0A1W6JPC3	Staphylococcus_phage	1.1e-36	42.0
WP_021299105.1\|1820705_1820948_+	hypothetical protein	NA	NA	NA	NA
WP_011529105.1\|1821203_1821536_+	hypothetical protein	NA	NA	NA	NA
WP_011529106.1\|1821532_1821754_+	hypothetical protein	NA	NA	NA	NA
WP_011529107.1\|1821756_1821948_+	hypothetical protein	NA	NA	NA	NA
WP_000206026.1\|1821959_1822322_+	hypothetical protein	NA	NA	NA	NA
WP_011529108.1\|1822318_1822648_+	hypothetical protein	NA	NA	NA	NA
WP_011529109.1\|1822650_1822923_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.6e-19	60.0
WP_011529110.1\|1822923_1823784_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	2.5e-119	72.0
WP_042769766.1\|1823858_1825298_+	DNA primase	Q9AZI5	Lactococcus_phage	1.1e-69	38.0
WP_042769761.1\|1825574_1825748_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	3.3e-10	57.9
WP_011529113.1\|1825753_1825927_+	hypothetical protein	NA	NA	NA	NA
WP_011529114.1\|1825928_1826195_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	8.9e-15	46.2
WP_011529115.1\|1826201_1826360_+	DUF2292 domain-containing protein	NA	NA	NA	NA
WP_011529116.1\|1826460_1827063_+	hypothetical protein	NA	NA	NA	NA
WP_011529117.1\|1827046_1827382_+	hypothetical protein	NA	NA	NA	NA
WP_011529118.1\|1827516_1827924_+	hypothetical protein	A0A1X9I6S2	Streptococcus_phage	4.7e-07	30.8
WP_012560493.1\|1828029_1828443_+	DUF1492 domain-containing protein	A0A1S5S8W3	Streptococcus_phage	5.1e-09	30.8
WP_011529120.1\|1828517_1828718_+	hypothetical protein	S6C469	Thermus_phage	5.1e-07	43.9
WP_011285285.1\|1828953_1829337_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	3.7e-14	41.7
WP_011285286.1\|1829501_1830155_+	hypothetical protein	NA	NA	NA	NA
WP_011529121.1\|1830550_1833106_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	6.8e-43	23.3
1830407:1830427	attR	NA	NA	NA	NA
WP_011529122.1\|1833092_1833299_-	YlbF family regulator	NA	NA	NA	NA
WP_002982171.1\|1833441_1833879_-	arginine repressor	NA	NA	NA	NA
WP_011529123.1\|1834169_1835861_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	1.1e-73	32.4

Anti-CRISPR protein detection

Acr_ID: NZ_LS483357.1|WP_010922205.1|628453_628687_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NZ_LS483357.1|WP_010922205.1|628453_628687_+|hypothetical-protein

628453_628687_+

77 aa aa

605451-662798

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NZ_LS483357_1	TypeI	1.5\|562871\|33\|NZ_LS483357\|PILER-CR,CRISPRCasFinder,CRT	562871-562903	33	630752-630720	1

1. spacer 1.5|562871|33|NZ_LS483357|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LS483357 position: 630752-630720, mismatch: 1

ttcatgagcttctttactctcaaagtaagagtg	CRISPR spacer
ttcatgagcttttttactctcaaagtaagagtg	Protospacer
***********.*********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483357

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information