CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483360	Streptococcus pyogenes strain NCTC10876 chromosome 1	1 crisprs	DEDDh,cas3,cas5,cas7,cas4,cas1,cas2,csm6,DinG,csa3	0	1	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483360_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483360_1

576945-577109

Unclear

I-C

Consensus_repeat	Method
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	CRISPRCasFinder

2 spacers

cas2,cas1,cas4,cas7,cas5

The CRISPR arrays of NZ_LS483360_1

>merge|NZ_LS483360|1|576945-577109|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAATAAACATTAAGGAAGTTATGCCAGAACCCAGAACAAGTCTCACCCTTCATGGGTGAGTGGATTGAAATGAGCCTCATGCCTCCAATTTTTTCGGGGTCGTTTTGTCTCACCCTTCATGGGTGAGTGGATTGAAA

>NZ_LS483360|1|1|576945-577109|CRISPRCasFinder
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TAAACATTAAGGAAGTTATGCCAGAACCCAGAACAA
GTCTCACCCTTCATGGGTGAGTGGATTGAAA	TGAGCCTCATGCCTCCAATTTTTTCGGGGTCGTTTT
GTCTCACCCTTCATGGGTGAGTGGATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483360.1\|WP_023610910.1\|583488_584205_+\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LS483360.1\|WP_014635589.1\|578658_579765_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483360.1\|WP_002983795.1\|584986_585667_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NZ_LS483360.1\|WP_011528828.1\|577269_577980_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483360.1\|WP_023610938.1\|573945_574794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_LS483360.1\|WP_002989044.1\|576502_576796_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LS483360.1\|WP_023610914.1\|565975_568624_+\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483360.1\|WP_002989018.1\|564413_564809_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181104
NZ_LS483360.1\|WP_023610901.1\|580589_582323_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483360.1\|WP_063632993.1\|565410_565974_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_LS483360.1\|WP_010922512.1\|571317_572046_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483360.1\|WP_023610917.1\|582395_583475_+\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483360.1\|WP_002989056.1\|584371_584845_-\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483360.1\|WP_002983803.1\|585940_587176_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NZ_LS483360.1\|WP_002989041.1\|575466_576492_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483360.1\|WP_014407721.1\|564831_565065_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483360.1\|WP_023610925.1\|579852_580593_+\|response-regulator	unknown	unknown	gnl\|CDD\|227095
NZ_LS483360.1\|WP_023610907.1\|574795_575470_+\|CRISPR-associated-protein-Cas4	cas4	COG1468_cas4_CAS-I-A:CAS-I-B:CAS-I-C:CAS-I-D:CAS-II-B	gnl\|CDD\|224385
NZ_LS483360.1\|WP_023612512.1\|577992_578616_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NZ_LS483360.1\|WP_002983750.1\|564138_564393_+\|DUF1912-family-protein	unknown	unknown	gnl\|CDD\|286073

Protein	Function_ID	Function_description	E-value
NZ_LS483360.1\|WP_023610910.1\|583488_584205_+\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	8.97595e-107
NZ_LS483360.1\|WP_014635589.1\|578658_579765_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	6.05633e-164
NZ_LS483360.1\|WP_002983795.1\|584986_585667_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.46736e-40
NZ_LS483360.1\|WP_011528828.1\|577269_577980_+\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	1.43593e-43
NZ_LS483360.1\|WP_023610938.1\|573945_574794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	6.79238e-160
NZ_LS483360.1\|WP_002989044.1\|576502_576796_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	1.60225e-34
NZ_LS483360.1\|WP_023610914.1\|565975_568624_+\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483360.1\|WP_002989018.1\|564413_564809_+\|hypothetical-protein	gnl\|CDD\|181104	PRK07758, PRK07758, hypothetical protein; Provisional.	0.000151325
NZ_LS483360.1\|WP_023610901.1\|580589_582323_+\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	3.63559e-66
NZ_LS483360.1\|WP_002983803.1\|585940_587176_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NZ_LS483360.1\|WP_010922512.1\|571317_572046_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	3.32713e-117
NZ_LS483360.1\|WP_023610917.1\|582395_583475_+\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	4.32233e-34
NZ_LS483360.1\|WP_002989056.1\|584371_584845_-\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	2.68589e-66
NZ_LS483360.1\|WP_063632993.1\|565410_565974_+\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.000900272
NZ_LS483360.1\|WP_002989041.1\|575466_576492_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483360.1\|WP_023610925.1\|579852_580593_+\|response-regulator	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	4.18348e-83
NZ_LS483360.1\|WP_023610907.1\|574795_575470_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	1.27553e-43
NZ_LS483360.1\|WP_023612512.1\|577992_578616_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.7195e-35
NZ_LS483360.1\|WP_002983750.1\|564138_564393_+\|DUF1912-family-protein	gnl\|CDD\|286073	pfam08930, DUF1912, Domain of unknown function (DUF1912). This domain has no known function. It is found in various Streptococcal proteins.	3.74168e-47

>NZ_LS483360.1|WP_002989044.1|576502_576796_+|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LS483360.1|WP_002989041.1|575466_576492_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LS483360.1|WP_023610907.1|574795_575470_+|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQVLHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSALRKEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMPSEEMDL
>NZ_LS483360.1|WP_023610938.1|573945_574794_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRVCEVFWFTHSSKLGNVSSARVFDLLEYHQSIEENSTYDVYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LS483360.1|WP_010922512.1|571317_572046_+|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIVDAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAFKAPEEIKSVNDECMEYDAMEKGEN
>NZ_LS483360.1|WP_023610914.1|565975_568624_+|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDNGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEDAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMKKIKS
>NZ_LS483360.1|WP_063632993.1|565410_565974_+|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEVARQTGMNLFHNHDSIDFVLRFMPWSQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVLFVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPSKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483360.1|WP_014407721.1|564831_565065_-|hypothetical-protein
MKPNNPYPAYTGQGRISCYDFRGTTTVSDHKMDLLLFISDFLSSATSLDICADFSTPPLSVTDQLNAPLIANILTNL
>NZ_LS483360.1|WP_002989018.1|564413_564809_+|hypothetical-protein
MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTISAGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKEWTEKDLLALKGIGPATVKKLVENGASFKK
>NZ_LS483360.1|WP_002983750.1|564138_564393_+|DUF1912-family-protein
MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDAFIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY
>NZ_LS483360.1|WP_011528828.1|577269_577980_+|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTITIFDKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVASGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHMLLLKKVGGVLIIVMGILLMTGTLNNLAQLFG
>NZ_LS483360.1|WP_023612512.1|577992_578616_+|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKDKMSTSKDKSMMTDKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH
>NZ_LS483360.1|WP_014635589.1|578658_579765_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKKVKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADLAIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSATEIKEKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE
>NZ_LS483360.1|WP_023610925.1|579852_580593_+|response-regulator
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLRKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQLVGVTPSQYKKGGQA
>NZ_LS483360.1|WP_023610901.1|580589_582323_+|sensor-histidine-kinase
MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATNSDLQAAVLVTKDGRTVSTNSQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSSKKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSKEMAAMKPYLAIKNGYAKDKSSFVYQRVIPNSQWTLIGVASLDQLHRVQRQIFWSFLGMGLLACLICGLTTILVLRKWIRPIQQLQQVILAIQKGNRQLRAQETGSPELTDLAHQFNALLDQIDSLMVAVADKEKEIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNDYIRLADELDHVSQYLFIQKQRYGDKLSYEVQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLMLTVWDNGKGIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMHELMADDTQENE
>NZ_LS483360.1|WP_023610917.1|582395_583475_+|MmcQ/YjbR-family-DNA-binding-protein
MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQLRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEATPFQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKKNWISIILDDKITDDKLWTLVTQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYITAPVKSIRYVCQVLETDIPNEGYRKNPNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYFKENN
>NZ_LS483360.1|WP_023610910.1|583488_584205_+|B3/4-domain-containing-protein
MVEFVADQSFWELFPGAKLGVVLLKDVQNQAESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPLVDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHATPSLHVLDKDNPHVPLFTEN
>NZ_LS483360.1|WP_002989056.1|584371_584845_-|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483360.1|WP_002983795.1|584986_585667_+|Crp/Fnr-family-transcriptional-regulator
MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFFEGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMTDVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLAILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDKDYFLQYTK
>NZ_LS483360.1|WP_002983803.1|585940_587176_+|arginine-deiminase
MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483360_1	1.1\|576976\|36\|NZ_LS483360\|CRISPRCasFinder	576976-577011	36	MK448764	Streptococcus phage Javan457, complete genome	22734-22769	2	0.944

1. spacer 1.1|576976|36|NZ_LS483360|CRISPRCasFinder matches to MK448764 (Streptococcus phage Javan457, complete genome) position: , mismatch: 2, identity: 0.944

taaacattaaggaagttatgccagaacccagaacaa	CRISPR spacer
caaacgttaaggaagttatgccagaacccagaacaa	Protospacer
.****.******************************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

36640 : 49026

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023610838.1\|36640_40366_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.7e-40	27.0
WP_009880323.1\|40599_42054_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
WP_023610840.1\|42081_43104_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	9.0e-63	41.4
WP_023079049.1\|43271_43826_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-25	36.1
WP_023610836.1\|44009_45557_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	E3SNU8	Prochlorococcus_phage	2.2e-44	51.8
WP_023610833.1\|45614_46739_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	1.0e-06	28.6
WP_023610831.1\|46991_48257_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_023079042.1\|48534_49026_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.4e-18	43.1

DBSCAN-SWA_2

758458 : 835059

Streptococcus_phage(55.36%)

capsid,portal,terminase,holin,integrase,protease,head,tRNA,tail

attL 747586:747602|attR 796989:797005

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
747586:747602	attL	NA	NA	NA	NA
WP_023610964.1\|758458_760723_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.2e-11	43.7
WP_023610967.1\|760979_761600_-	DUF3862 domain-containing protein	NA	NA	NA	NA
WP_085577338.1\|761962_763051_-\|integrase	site-specific integrase	Q38159	Streptococcus_phage	8.9e-202	98.3
WP_011106738.1\|763170_763476_-	membrane protein	NA	NA	NA	NA
WP_021340822.1\|763485_764274_-	peptidase S24	A0A1S5SD15	Streptococcus_phage	2.9e-85	62.6
WP_080465047.1\|764646_764805_+	hypothetical protein	J7KH24	Streptococcus_phage	3.4e-22	92.3
WP_085577339.1\|764938_765724_-	hypothetical protein	A0A1S5S7L0	Streptococcus_phage	4.8e-48	57.4
WP_021340823.1\|765780_765927_+	hypothetical protein	NA	NA	NA	NA
WP_023605145.1\|765923_766406_-	hypothetical protein	NA	NA	NA	NA
WP_021340169.1\|766479_766719_+	helix-turn-helix transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	3.1e-35	97.5
WP_002984287.1\|766730_766976_+	hypothetical protein	A0A097PAP6	Streptococcus_pyogenes_phage	1.2e-34	95.1
WP_111681188.1\|767199_767550_+	hypothetical protein	NA	NA	NA	NA
WP_032461901.1\|767524_767839_-	hypothetical protein	NA	NA	NA	NA
WP_032461902.1\|767981_768167_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	4.7e-23	85.2
WP_011017882.1\|768245_768542_+	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	3.1e-48	98.0
WP_011017881.1\|768538_768676_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_085577340.1\|768756_769086_+	hypothetical protein	J7KBZ0	Streptococcus_phage	3.6e-13	41.8
WP_002984315.1\|769085_769280_+	hypothetical protein	J7KK69	Streptococcus_phage	3.9e-12	54.2
WP_011284877.1\|769276_769561_+	hypothetical protein	NA	NA	NA	NA
WP_014635524.1\|769557_770241_+	AAA family ATPase	J7KC09	Streptococcus_phage	4.6e-124	98.2
WP_085577341.1\|770276_771680_+	DEAD/DEAH box helicase	A0A1P8BMH7	Lactococcus_phage	2.3e-194	72.1
WP_085577342.1\|771684_772167_+	DUF669 domain-containing protein	A0A1P8BM40	Lactococcus_phage	1.7e-59	70.7
WP_011017876.1\|772184_773738_+	hypothetical protein	A0A1P8BM51	Lactococcus_phage	1.5e-210	70.6
WP_085577343.1\|774006_774876_+	bifunctional DNA primase/polymerase	A0A1P8BME8	Lactococcus_phage	7.5e-103	65.2
WP_023079767.1\|774829_775180_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	9.9e-46	88.5
WP_011018138.1\|775163_775520_+	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	5.0e-61	100.0
WP_085577344.1\|776040_776454_+	hypothetical protein	Q938M1	Temperate_phage	7.1e-35	63.1
WP_085577345.1\|776450_776657_+	hypothetical protein	Q938M0	Temperate_phage	1.0e-10	100.0
WP_011017866.1\|776680_777121_+	ArpU family transcriptional regulator	Q938L8	Temperate_phage	5.0e-79	100.0
WP_063632710.1\|777767_778106_+	HNH endonuclease	J7KH36	Streptococcus_phage	2.4e-57	97.2
WP_002985371.1\|778276_778744_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_085577347.1\|778746_778977_+	hypothetical protein	NA	NA	NA	NA
WP_063632717.1\|778980_780735_+\|terminase	terminase large subunit	J7KKD1	Streptococcus_phage	0.0e+00	95.9
WP_002985365.1\|780731_780902_+	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_002985363.1\|780894_781119_+	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_011017578.1\|781152_782373_+\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_032465106.1\|782350_783016_+\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	1.9e-90	77.7
WP_011017580.1\|783040_784228_+\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
WP_063812171.1\|784372_784675_+\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	5.7e-42	88.8
WP_063812172.1\|784671_785019_+\|head	phage head closure protein	J7KJ42	Streptococcus_phage	6.5e-50	87.3
WP_085577348.1\|785015_785393_+	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	3.7e-46	72.8
WP_011017584.1\|785389_785815_+	hypothetical protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
WP_011017585.1\|785830_786439_+	hypothetical protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
WP_011017586.1\|786491_786818_+	hypothetical protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
WP_021299462.1\|786865_787015_+	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_085577349.1\|787027_790951_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.9e-238	48.6
WP_085577350.1\|790950_791658_+\|tail	phage tail protein	Q938K2	Temperate_phage	5.4e-91	69.4
WP_085577351.1\|791654_793799_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	97.5
WP_111695808.1\|793795_794809_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	2.3e-183	99.1
WP_111695809.1\|794823_796710_+	gp58-like family protein	Q938J9	Temperate_phage	1.9e-159	72.3
WP_085577293.1\|796718_796880_+	hypothetical protein	NA	NA	NA	NA
WP_085577294.1\|796882_797494_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	4.4e-81	90.6
796989:797005	attR	NA	NA	NA	NA
WP_011017397.1\|797503_797776_+	hypothetical protein	A7J2B2	Streptococcus_phage	5.5e-36	91.0
WP_003058873.1\|797772_798000_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_011284838.1\|798116_799451_+	lysin	Q5MY96	Streptococcus_phage	1.3e-247	93.0
WP_002985327.1\|799526_800234_-	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_011184727.1\|800344_801103_-	DNase Mf2	NA	NA	NA	NA
WP_002993136.1\|801342_801531_+	hypothetical protein	A3F673	Streptococcus_phage	2.1e-18	76.3
WP_002989607.1\|802121_802736_+	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	6.2e-51	52.3
WP_023078569.1\|802866_803652_-	hypothetical protein	NA	NA	NA	NA
WP_023078568.1\|803661_804360_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	5.1e-09	27.3
WP_002989617.1\|804359_804731_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023610966.1\|804915_808026_+	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	1.4e-119	29.9
WP_010922375.1\|808105_809119_+	6-phosphofructokinase	NA	NA	NA	NA
WP_002984447.1\|809181_810684_+	pyruvate kinase	NA	NA	NA	NA
WP_002984449.1\|810901_811459_+	signal peptidase I	NA	NA	NA	NA
WP_011284834.1\|811634_813449_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	1.2e-97	38.7
WP_002989626.1\|813644_813980_+	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002992417.1\|814086_814728_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_023610961.1\|814737_815367_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-27	35.5
WP_023610973.1\|815382_816219_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023610969.1\|816588_817362_+	CAMP factor pore-forming toxin Cfa	NA	NA	NA	NA
WP_020833513.1\|817730_818966_-	cation diffusion facilitator family transporter	NA	NA	NA	NA
WP_023610963.1\|819085_820408_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_111695810.1\|820938_823257_+	DNA helicase PcrA	A7KV33	Bacillus_phage	1.0e-130	41.0
WP_002984469.1\|823619_823868_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002984470.1\|823904_824516_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_002984473.1\|824526_824715_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_002984475.1\|824727_825267_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984476.1\|825307_825508_+	CsbD family protein	J7KJ36	Streptococcus_phage	1.8e-07	50.0
WP_002994467.1\|825518_826007_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_002984480.1\|826169_826811_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023610811.1\|826933_827497_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_002989664.1\|827614_828316_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.9e-36	37.0
WP_023610819.1\|828330_830967_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_002993908.1\|831058_831655_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_085577296.1\|831665_832622_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_023605124.1\|832718_834059_+	DUF2130 domain-containing protein	NA	NA	NA	NA
WP_002989678.1\|834174_835059_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA

DBSCAN-SWA_3

1045948 : 1081137

Streptococcus_phage(67.35%)

capsid,portal,terminase,holin,integrase,tail

attL 1055448:1055463|attR 1080215:1080230

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111695817.1\|1045948_1046404_-\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	1.4e-63	82.1
WP_111695818.1\|1046413_1047025_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	7.7e-78	87.7
WP_012560658.1\|1047027_1047189_-	hypothetical protein	NA	NA	NA	NA
WP_111695819.1\|1047200_1048985_-	hypothetical protein	Q938J9	Temperate_phage	2.8e-96	48.7
WP_168390558.1\|1048999_1050022_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-149	83.4
WP_172451686.1\|1050021_1052001_-\|tail	phage tail protein	M1PKG3	Streptococcus_phage	6.3e-105	51.4
WP_063629041.1\|1051982_1052678_-	hypothetical protein	A0A1B1P761	Bacillus_phage	2.6e-05	29.6
WP_111695821.1\|1052674_1055032_-	hypothetical protein	M1NRG5	Streptococcus_phage	3.9e-138	48.4
WP_011528785.1\|1055031_1055403_-	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
WP_003047548.1\|1055417_1055681_-	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.7e-18	54.7
1055448:1055463	attL	NA	NA	NA	NA
WP_172451687.1\|1055691_1056282_-\|tail	phage tail protein	M1PKG8	Streptococcus_phage	1.0e-58	61.4
WP_000573598.1\|1056297_1056633_-	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_111695823.1\|1056633_1056870_-	hypothetical protein	M1NRG9	Streptococcus_phage	9.6e-21	70.5
WP_011054681.1\|1056862_1057201_-	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_109828577.1\|1057160_1057583_-	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	4.8e-47	67.9
WP_053308481.1\|1057733_1058627_-\|capsid	phage major capsid protein	A0A126GGI3	Streptococcus_phage	6.3e-129	77.4
WP_053308482.1\|1058630_1059095_-	DUF4355 domain-containing protein	A0A141E167	Streptococcus_phage	6.3e-40	57.8
WP_111695824.1\|1059175_1060591_-\|terminase	terminase	A0A0B5A091	Streptococcus_phage	8.5e-213	74.2
WP_011888764.1\|1060672_1060909_-	hypothetical protein	M1IRA5	Streptococcus_phage	1.2e-31	80.3
WP_002986828.1\|1060910_1061177_-	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_032461150.1\|1061169_1061349_-	hypothetical protein	NA	NA	NA	NA
WP_002994100.1\|1061398_1061623_-	hypothetical protein	NA	NA	NA	NA
WP_011017978.1\|1061628_1063122_-	hypothetical protein	M1Q184	Streptococcus_phage	3.7e-89	55.6
WP_011017979.1\|1063114_1064383_-\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	2.4e-190	76.2
WP_109828582.1\|1064379_1064736_-	hypothetical protein	A0A0B5A7G9	Streptococcus_phage	1.7e-08	40.9
WP_011017980.1\|1064885_1065230_-	HNH endonuclease	M1Q0W7	Streptococcus_phage	2.5e-41	69.4
WP_010922470.1\|1065337_1065757_-	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	8.7e-57	79.9
WP_032460172.1\|1066121_1066415_-	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	2.7e-49	99.0
WP_023077953.1\|1066462_1067227_-	site-specific DNA-methyltransferase	A0A1S5SE41	Streptococcus_phage	2.8e-133	91.9
WP_011017571.1\|1067216_1067699_-	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_111695825.1\|1067702_1067972_-	hypothetical protein	A7J287	Streptococcus_phage	1.9e-25	73.0
WP_111695826.1\|1067976_1068162_-	hypothetical protein	A3F626	Streptococcus_phage	3.5e-10	83.8
WP_111695827.1\|1068148_1068661_-	hypothetical protein	A0A1S5S8V7	Streptococcus_phage	3.2e-61	71.4
WP_111695828.1\|1068657_1068999_-	hypothetical protein	M1PKX3	Streptococcus_phage	3.7e-13	37.5
WP_011888756.1\|1069193_1070222_-	DUF1351 domain-containing protein	E8ZD61	Streptococcus_phage	9.5e-121	65.9
WP_111695829.1\|1070231_1071056_-	phage recombination protein Bet	A0A1S5SFP4	Streptococcus_phage	1.1e-114	77.6
WP_111695868.1\|1071058_1071388_-	hypothetical protein	J7KGX3	Streptococcus_phage	7.1e-46	84.4
WP_111695830.1\|1071564_1071819_-	hypothetical protein	Q938N0	Temperate_phage	1.8e-36	89.3
WP_000166038.1\|1071829_1071970_-	hypothetical protein	A0A1X9I6Y1	Streptococcus_phage	2.6e-05	54.5
WP_002985387.1\|1071966_1072200_-	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_172451688.1\|1072180_1072594_-	DnaD domain protein	Q938N2	Temperate_phage	5.4e-59	84.7
WP_076634492.1\|1072662_1072932_-	transcriptional regulator	A0A060QMU7	Streptococcus_phage	2.5e-12	46.3
WP_032461153.1\|1073031_1073217_-	hypothetical protein	Q938N3	Temperate_phage	1.8e-22	90.2
WP_032461154.1\|1073218_1073530_-	hypothetical protein	A1EAC3	Streptococcus_phage	1.7e-49	86.4
WP_011889039.1\|1073636_1073819_+	hypothetical protein	NA	NA	NA	NA
WP_111695831.1\|1073959_1074676_-	phage antirepressor KilAC domain-containing protein	C9WB91	Streptococcus_virus	4.7e-103	76.3
WP_002993390.1\|1074687_1074879_-	hypothetical protein	A7J270	Streptococcus_phage	4.0e-25	92.1
WP_020837683.1\|1075514_1075610_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_002994741.1\|1076032_1076380_+	helix-turn-helix transcriptional regulator	A0A1S5SEQ8	Streptococcus_phage	1.2e-40	72.6
WP_002994744.1\|1076383_1076764_+	ImmA/IrrE family metallo-endopeptidase	A0A1S5SFH2	Streptococcus_phage	8.0e-41	61.1
WP_002994745.1\|1076775_1077042_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_011528538.1\|1077168_1078308_+\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	4.4e-119	55.8
WP_023610978.1\|1078390_1079431_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.5e-68	43.9
WP_002990099.1\|1079674_1080268_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
1080215:1080230	attR	NA	NA	NA	NA
WP_014407521.1\|1080267_1081137_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	5.4e-101	64.2

DBSCAN-SWA_4

1185609 : 1196212

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011184383.1\|1185609_1186752_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	1.4e-24	27.3
WP_012560601.1\|1186986_1187427_+	hypothetical protein	NA	NA	NA	NA
WP_023610854.1\|1187456_1188725_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_023610863.1\|1188812_1190165_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.6e-30	24.2
WP_002985134.1\|1190385_1190727_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
WP_002985136.1\|1190787_1191954_-	chorismate synthase	A0A291AU41	Pandoravirus	4.5e-34	32.8
WP_023610850.1\|1192047_1192734_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	5.4e-88	68.9
WP_011054349.1\|1192730_1193894_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	5.8e-143	65.1
WP_011054348.1\|1194001_1196212_+	LTA synthase family protein	W6LM83	Streptococcus_phage	2.9e-268	69.1

DBSCAN-SWA_5

1227907 : 1276925

Temperate_phage(59.02%)

capsid,portal,terminase,holin,integrase,tRNA,tail

attL 1218441:1218456|attR 1282962:1282977

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1218441:1218456	attL	NA	NA	NA	NA
WP_111695834.1\|1227907_1228825_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	2.1e-34	37.5
WP_023610402.1\|1228928_1229597_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-30	36.2
WP_010922123.1\|1229606_1230683_-	ABC transporter permease	NA	NA	NA	NA
WP_002990406.1\|1230755_1231142_-	YbgA family protein	NA	NA	NA	NA
WP_002993028.1\|1231134_1231512_-	OsmC family protein	NA	NA	NA	NA
WP_002986897.1\|1231760_1231943_-	hypothetical protein	A3F673	Streptococcus_phage	6.9e-19	78.3
WP_002986898.1\|1232153_1232393_+	hypothetical protein	NA	NA	NA	NA
WP_002986905.1\|1232432_1232906_+	hypothetical protein	A3F671	Streptococcus_phage	1.6e-78	92.3
WP_002986907.1\|1232907_1233264_+	hypothetical protein	NA	NA	NA	NA
WP_011054729.1\|1233331_1234198_-	DUF334 domain-containing protein	Q938J2	Temperate_phage	3.7e-134	100.0
WP_011017840.1\|1234185_1234710_-	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_023611747.1\|1234849_1236052_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	4.6e-236	97.5
WP_000609113.1\|1236167_1236395_-\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_002987582.1\|1236391_1236667_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_032461328.1\|1236676_1237294_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	1.7e-77	88.8
WP_002987513.1\|1237296_1237728_-	DUF1617 family protein	Q938J8	Temperate_phage	1.1e-73	100.0
WP_111695835.1\|1237739_1239623_-	gp58-like family protein	Q938J9	Temperate_phage	1.6e-251	96.2
WP_111695836.1\|1239632_1240649_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.1e-180	98.2
WP_111695837.1\|1240645_1242790_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	98.5
WP_011054737.1\|1242786_1243503_-\|tail	phage tail family protein	Q938K2	Temperate_phage	2.9e-137	100.0
WP_111695838.1\|1243499_1246760_-	tape measure protein	Q938K3	Temperate_phage	0.0e+00	97.1
WP_011284973.1\|1246749_1247331_-	hypothetical protein	Q938K4	Temperate_phage	4.9e-106	99.5
WP_011054740.1\|1247334_1247769_-	hypothetical protein	Q938K5	Temperate_phage	2.6e-72	100.0
WP_011054741.1\|1247807_1248293_-	hypothetical protein	Q938K6	Temperate_phage	1.6e-86	100.0
WP_010922084.1\|1248292_1248691_-\|capsid	phage capsid protein	Q79S87	Temperate_phage	3.5e-71	100.0
WP_111695839.1\|1248687_1249044_-\|capsid	capsid protein	Q79S88	Temperate_phage	5.0e-61	98.3
WP_010922082.1\|1249043_1249376_-	hypothetical protein	Q79S86	Temperate_phage	9.6e-59	100.0
WP_010922081.1\|1249365_1249782_-	hypothetical protein	Q938K7	Temperate_phage	4.3e-56	99.1
WP_010922080.1\|1249835_1250654_-\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	4.0e-146	100.0
WP_010922079.1\|1250657_1251272_-	hypothetical protein	Q938K8	Temperate_phage	3.1e-95	95.0
WP_011888689.1\|1251397_1251664_-	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_010922077.1\|1251750_1251978_-	hypothetical protein	NA	NA	NA	NA
WP_111695840.1\|1251977_1253471_-\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	3.1e-213	80.0
WP_010922075.1\|1253475_1254978_-\|portal	phage portal protein	Q938L2	Temperate_phage	5.9e-281	99.6
WP_010922074.1\|1254991_1256203_-\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_023612332.1\|1256285_1256759_-	hypothetical protein	Q938L4	Temperate_phage	7.3e-76	98.7
WP_002986841.1\|1256809_1257187_-	ASCH domain-containing protein	Q938L5	Temperate_phage	1.7e-67	100.0
WP_076639321.1\|1257247_1257631_-	GNAT family N-acetyltransferase	B5SP24	Lactococcus_phage	3.9e-35	58.5
WP_002986850.1\|1257639_1258317_-	hypothetical protein	Q938L6	Temperate_phage	8.7e-131	100.0
WP_002986854.1\|1258295_1258814_-	ParB N-terminal domain-containing protein	Q938L7	Temperate_phage	1.5e-90	100.0
WP_011054748.1\|1258894_1259152_+	hypothetical protein	NA	NA	NA	NA
WP_021340586.1\|1259726_1260164_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	1.4e-76	99.3
WP_010922070.1\|1260430_1261066_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	2.0e-89	69.4
WP_111695841.1\|1261067_1261352_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
WP_023610894.1\|1261361_1261631_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	1.2e-43	91.0
WP_111695842.1\|1261627_1261912_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	1.0e-48	96.8
WP_011017567.1\|1261905_1262103_-	hypothetical protein	A3F626	Streptococcus_phage	9.9e-11	86.5
WP_111695843.1\|1262089_1262602_-	hypothetical protein	Q708P9	Streptococcus_phage	3.4e-63	73.8
WP_002990067.1\|1262598_1262937_-	hypothetical protein	M1PKX3	Streptococcus_phage	4.0e-12	37.5
WP_009880273.1\|1263113_1263281_-	hypothetical protein	A0A1S5SEF3	Streptococcus_phage	6.0e-09	55.6
WP_111695844.1\|1263290_1264088_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	5.8e-126	82.3
WP_000594115.1\|1264080_1264281_-	hypothetical protein	NA	NA	NA	NA
WP_111695845.1\|1264277_1265204_-	recombinase RecT	M1NRN6	Streptococcus_phage	1.2e-90	71.8
WP_032463369.1\|1265206_1265536_-	hypothetical protein	J7KGX3	Streptococcus_phage	1.1e-46	87.2
WP_011017565.1\|1265591_1265798_-	hypothetical protein	NA	NA	NA	NA
WP_011017992.1\|1265806_1265947_-	hypothetical protein	NA	NA	NA	NA
WP_002986875.1\|1265952_1266165_-	hypothetical protein	Q938N1	Temperate_phage	5.4e-15	58.6
WP_172450154.1\|1266145_1266556_-	DnaD domain protein	Q938N2	Temperate_phage	1.3e-52	78.1
WP_019418742.1\|1266677_1266935_-	hypothetical protein	A0A141E1D1	Streptococcus_phage	8.9e-12	40.5
WP_002986881.1\|1267028_1267214_-	hypothetical protein	Q938N3	Temperate_phage	1.2e-23	95.1
WP_032463372.1\|1267242_1267500_-	hypothetical protein	NA	NA	NA	NA
WP_023611028.1\|1267605_1267821_+	hypothetical protein	A0A1S5SA41	Streptococcus_phage	1.9e-15	61.4
WP_023611035.1\|1267794_1268043_-	hypothetical protein	A0A141E1M0	Streptococcus_phage	1.6e-26	69.5
WP_111695846.1\|1268121_1268322_+	KTSC domain-containing protein	A0A1S5S8T9	Streptococcus_phage	1.1e-20	72.3
WP_002986888.1\|1268318_1268468_-	hypothetical protein	Q938N4	Temperate_phage	1.8e-20	100.0
WP_002986890.1\|1268500_1269229_-	phage antirepressor KilAC domain-containing protein	Q938N5	Temperate_phage	3.4e-133	99.6
WP_002986891.1\|1269239_1269431_-	hypothetical protein	A7J270	Streptococcus_phage	1.2e-24	90.5
WP_020837683.1\|1270065_1270161_+	type I toxin-antitoxin system Fst family toxin	NA	NA	NA	NA
WP_011054768.1\|1270579_1270939_+	helix-turn-helix transcriptional regulator	Q938N6	Temperate_phage	1.1e-60	100.0
WP_002986894.1\|1270952_1271333_+	hypothetical protein	Q938N7	Temperate_phage	5.3e-69	100.0
WP_002986895.1\|1271343_1271865_+	hypothetical protein	Q938N8	Temperate_phage	2.3e-67	100.0
WP_080277749.1\|1271983_1273138_+\|integrase	site-specific integrase	Q938N9	Temperate_phage	1.1e-205	99.7
WP_085577314.1\|1273266_1275672_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_032464300.1\|1275881_1276925_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	2.7e-30	34.3
1282962:1282977	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1420490 : 1426861

Streptococcus_phage(66.67%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023610462.1\|1420490_1421168_-	asparagine synthetase A	A0A167RLM0	Powai_lake_megavirus	2.4e-11	28.6
WP_011017510.1\|1421191_1421530_-	Fic family protein	NA	NA	NA	NA
WP_011528388.1\|1421922_1422231_-	hypothetical protein	Q6DMT0	Streptococcus_phage	5.7e-21	64.9
WP_023610443.1\|1422296_1422749_-\|portal	phage portal protein	E4ZFM3	Streptococcus_phage	4.4e-62	85.6
WP_023610483.1\|1422843_1423125_-	hypothetical protein	E4ZFM1	Streptococcus_phage	3.2e-07	50.7
WP_002985606.1\|1423143_1423449_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011054283.1\|1423448_1423751_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_002990640.1\|1423805_1423982_-	hypothetical protein	M1PSF2	Streptococcus_phage	3.8e-22	87.9
WP_165745700.1\|1423997_1424891_+	hypothetical protein	NA	NA	NA	NA
WP_023610394.1\|1424890_1425121_+	hypothetical protein	NA	NA	NA	NA
WP_085577319.1\|1425111_1426662_+	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_023610427.1\|1426651_1426861_+	helix-turn-helix domain-containing protein	A0A2K5B263	Erysipelothrix_phage	3.4e-17	63.1

DBSCAN-SWA_7

1478961 : 1539010

Streptococcus_phage(33.33%)

tRNA,bacteriocin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003060803.1\|1478961_1479162_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|1479174_1479402_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|1480624_1480807_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002994504.1\|1480821_1481067_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002985741.1\|1482023_1482500_-	NUDIX hydrolase	NA	NA	NA	NA
WP_002985743.1\|1482519_1483416_-	GTPase Era	NA	NA	NA	NA
WP_002985746.1\|1483535_1483943_-	diacylglycerol kinase	NA	NA	NA	NA
WP_002985748.1\|1483923_1484421_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_009880369.1\|1484579_1485155_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_010921967.1\|1485200_1486253_-	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_010921966.1\|1486411_1488184_-	oleate hydratase	NA	NA	NA	NA
WP_023610441.1\|1488497_1489646_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.4e-16	40.5
WP_002985757.1\|1489801_1490017_-	YozE family protein	NA	NA	NA	NA
WP_010921964.1\|1490013_1490523_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_020833311.1\|1490595_1491453_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985763.1\|1491561_1492119_-	ribosome recycling factor	NA	NA	NA	NA
WP_002985765.1\|1492147_1492876_-	UMP kinase	NA	NA	NA	NA
WP_002985768.1\|1493197_1493887_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002990800.1\|1493992_1494418_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_010921962.1\|1494661_1495015_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_023610449.1\|1495084_1497490_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_002990808.1\|1497706_1498513_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_011017448.1\|1498660_1499515_-	metal ABC transporter permease	NA	NA	NA	NA
WP_002985780.1\|1499515_1500241_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.4e-17	32.6
WP_004218965.1\|1500304_1501237_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023610422.1\|1501382_1502030_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_023610418.1\|1502129_1502471_-	hypothetical protein	NA	NA	NA	NA
WP_023610413.1\|1502621_1503317_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002993069.1\|1503336_1503588_-	hypothetical protein	NA	NA	NA	NA
WP_002985793.1\|1503587_1504142_-	NUDIX hydrolase	NA	NA	NA	NA
WP_023610405.1\|1504172_1505555_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	5.0e-32	36.4
WP_023610456.1\|1505727_1507065_-	MFS transporter	NA	NA	NA	NA
WP_023610399.1\|1507397_1508357_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_023610469.1\|1508432_1509131_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	2.4e-11	25.2
WP_002990844.1\|1509123_1509360_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_023610476.1\|1509720_1510362_+	hypothetical protein	NA	NA	NA	NA
WP_021340584.1\|1510455_1510707_-	hypothetical protein	NA	NA	NA	NA
WP_023610434.1\|1510947_1511352_-	hypothetical protein	NA	NA	NA	NA
WP_023610485.1\|1511748_1512225_-	hypothetical protein	NA	NA	NA	NA
WP_023610444.1\|1514012_1514390_-	hypothetical protein	NA	NA	NA	NA
WP_111695856.1\|1514887_1515463_-	hypothetical protein	NA	NA	NA	NA
WP_023610438.1\|1515921_1516674_+	ADP-ribosyltransferase	NA	NA	NA	NA
WP_023610421.1\|1516877_1519064_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.2e-168	44.3
WP_002985812.1\|1519030_1519519_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_010921941.1\|1519522_1520536_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.5e-97	53.7
WP_080263221.1\|1521029_1523030_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	1.5e-85	34.9
WP_023610445.1\|1523269_1523977_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_085577371.1\|1524750_1529688_-\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_002985826.1\|1529952_1531134_-	L-lactate oxidase	NA	NA	NA	NA
WP_023610361.1\|1531367_1532195_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	3.2e-127	79.1
WP_023610367.1\|1532268_1532625_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.7e-40	66.7
WP_111695857.1\|1532924_1533554_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_011017426.1\|1533600_1533993_-	hypothetical protein	NA	NA	NA	NA
WP_021733048.1\|1534019_1534883_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	74.7
WP_002985838.1\|1534887_1535211_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_023610359.1\|1535614_1535854_-	hypothetical protein	NA	NA	NA	NA
WP_023610380.1\|1535872_1536748_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.7e-73	48.6
WP_023610360.1\|1536765_1537401_-	dTMP kinase	M1PSC7	Streptococcus_phage	1.4e-66	64.4
WP_002985847.1\|1537649_1537925_-	YlbG family protein	NA	NA	NA	NA
WP_002985850.1\|1538419_1539010_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7

DBSCAN-SWA_8

1734948 : 1847684

113

Streptococcus_phage(62.9%)

capsid,portal,terminase,holin,integrase,protease,head,tRNA,bacteriocin,tail

attL 1765269:1765294|attR 1796951:1796976

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023610712.1\|1734948_1735254_-\|protease	Spi family protease inhibitor	NA	NA	NA	NA
WP_023610705.1\|1735255_1736452_-	cysteine proteinase exotoxin SpeB	NA	NA	NA	NA
WP_023610751.1\|1736723_1736894_-	hypothetical protein	NA	NA	NA	NA
WP_002982409.1\|1737392_1738235_+	transcriptional regulator	NA	NA	NA	NA
WP_010922721.1\|1738475_1739291_-	streptodornase B	A7J2B8	Streptococcus_phage	6.7e-29	33.3
WP_011185025.1\|1739654_1740164_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	1.1e-37	53.5
WP_023610739.1\|1740245_1741334_-	glycerol dehydrogenase	NA	NA	NA	NA
WP_023610763.1\|1741390_1742059_-	fructose-6-phosphate aldolase	E3SKN5	Synechococcus_phage	2.6e-26	34.7
WP_023079149.1\|1742073_1744491_-	glycyl radical protein	Q66LZ4	Escherichia_phage	3.6e-09	52.8
WP_023610767.1\|1744701_1746006_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002992103.1\|1746015_1746324_-	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002992105.1\|1746351_1746672_-	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002982359.1\|1746959_1747940_-	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_032465931.1\|1747955_1748702_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002992110.1\|1748827_1749601_+	glycyl-radical enzyme activating protein	A0A0U2DAM7	Escherichia_phage	3.8e-05	36.2
WP_002982348.1\|1749836_1750013_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002982344.1\|1750026_1750179_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_111695863.1\|1750227_1752564_-	penicillin-binding protein	NA	NA	NA	NA
WP_002982339.1\|1752602_1752983_-	RidA family protein	NA	NA	NA	NA
WP_011285240.1\|1753558_1754560_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	3.7e-05	26.6
WP_023610749.1\|1754648_1756289_-	hypothetical protein	NA	NA	NA	NA
WP_023610765.1\|1756535_1758035_+	C69 family dipeptidase	NA	NA	NA	NA
WP_023610701.1\|1758746_1759013_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002982320.1\|1759263_1760895_-	chaperonin GroEL	A0A240F779	uncultured_virus	1.8e-153	55.1
WP_002991292.1\|1760930_1761221_-	co-chaperone GroES	NA	NA	NA	NA
WP_023610724.1\|1761398_1763843_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	4.1e-122	39.0
WP_023610213.1\|1763842_1764304_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_002991299.1\|1764499_1764703_-	cold-shock protein	Q9AZD3	Lactococcus_phage	6.1e-24	80.0
1765269:1765294	attL	NA	NA	NA	NA
WP_063629765.1\|1765292_1766363_-\|integrase	site-specific integrase	A0A1P8VVR7	Streptococcus_phage	9.6e-92	48.3
WP_111685849.1\|1766490_1766793_-	hypothetical protein	A0A1S5SAH9	Streptococcus_phage	1.5e-21	53.6
WP_063629763.1\|1766785_1767172_-	hypothetical protein	Q938N7	Temperate_phage	2.4e-37	61.6
WP_063629762.1\|1767175_1767526_-	helix-turn-helix transcriptional regulator	A0A1S5S8C4	Streptococcus_phage	8.1e-40	70.6
WP_111685850.1\|1767922_1768132_+	helix-turn-helix transcriptional regulator	A0A1P8VVQ4	Streptococcus_phage	3.0e-26	88.2
WP_063629760.1\|1768131_1768494_+	hypothetical protein	A0A1P8VVU1	Streptococcus_phage	6.6e-37	68.8
WP_063629759.1\|1768515_1768800_+	hypothetical protein	B3GVX8	Streptococcus_phage	3.5e-41	81.9
WP_063629758.1\|1768826_1769045_+	hypothetical protein	A0A1P8VVV1	Streptococcus_phage	3.9e-24	83.3
WP_111685851.1\|1769053_1770400_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	9.3e-209	83.7
WP_111685852.1\|1770386_1771133_+	conserved phage C-terminal domain-containing protein	A0A1P8VVR3	Streptococcus_phage	3.5e-133	96.0
WP_111685853.1\|1771133_1771955_+	ATP-binding protein	A0A1P8VVV9	Streptococcus_phage	1.1e-148	95.2
WP_063629755.1\|1771954_1772182_+	hypothetical protein	C5J991	Streptococcus_phage	1.3e-11	46.6
WP_168388561.1\|1772195_1772366_+	hypothetical protein	Q938M0	Temperate_phage	2.5e-10	96.8
WP_109982045.1\|1772362_1772632_+	hypothetical protein	A7J287	Streptococcus_phage	1.4e-28	77.5
WP_111685854.1\|1772634_1773384_+	site-specific DNA-methyltransferase	Q9MCL7	Streptococcus_virus	7.3e-131	89.5
WP_111685855.1\|1774189_1774408_+	hypothetical protein	NA	NA	NA	NA
WP_032460876.1\|1774404_1774797_+	single-stranded DNA-binding protein	A0A1P8VVS8	Streptococcus_phage	4.1e-48	71.7
WP_029713970.1\|1774810_1775089_+	hypothetical protein	A3F632	Streptococcus_phage	9.6e-44	96.7
WP_063629751.1\|1775183_1775411_+	hypothetical protein	NA	NA	NA	NA
WP_063629750.1\|1775382_1775847_+	hypothetical protein	A0A1P8VVT5	Streptococcus_phage	5.8e-78	92.2
WP_063629749.1\|1775956_1776499_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	8.3e-100	98.9
WP_063629748.1\|1776668_1776851_+	hypothetical protein	A0A1S5SAV8	Streptococcus_phage	6.5e-09	51.7
WP_111685856.1\|1777116_1777434_+	HNH endonuclease	A0A1S5SD32	Streptococcus_phage	6.4e-52	90.5
WP_000601034.1\|1777551_1778037_+	hypothetical protein	A0A1S5SCZ6	Streptococcus_phage	3.2e-79	98.1
WP_111685857.1\|1778029_1779742_+\|terminase	terminase large subunit	A0A1S5SCW2	Streptococcus_phage	0.0e+00	97.0
WP_111685858.1\|1779750_1780893_+\|portal	phage portal protein	A0A1P8VVT4	Streptococcus_phage	5.3e-213	98.2
WP_063629746.1\|1780943_1781486_+\|head,protease	HK97 family phage prohead protease	A0A1P8VVX2	Streptococcus_phage	6.8e-94	96.7
WP_063629745.1\|1781496_1782759_+\|capsid	phage major capsid protein	A0A1P8VVT0	Streptococcus_phage	5.8e-197	85.6
WP_032460894.1\|1782778_1783117_+	hypothetical protein	A0A1P8VVS7	Streptococcus_phage	1.2e-45	80.6
WP_032460893.1\|1783113_1783419_+\|head,tail	head-tail adaptor protein	A0A1P8VVX4	Streptococcus_phage	5.4e-40	84.2
WP_032460892.1\|1783418_1783766_+	hypothetical protein	A0A1P8VVS6	Streptococcus_phage	3.6e-56	92.2
WP_063629744.1\|1783752_1784097_+	hypothetical protein	A0A1P8VVU6	Streptococcus_phage	8.8e-55	92.1
WP_063629743.1\|1784111_1784783_+\|tail	phage tail protein	A0A1P8VVR1	Streptococcus_phage	7.6e-111	89.9
WP_063629742.1\|1784786_1785260_+	hypothetical protein	A0A0A0YX24	Streptococcus_phage	9.2e-79	90.4
WP_111685860.1\|1785449_1788185_+\|tail	phage tail tape measure protein	A0A1P8VVW8	Streptococcus_phage	4.7e-244	90.5
WP_063629740.1\|1788181_1788904_+	hypothetical protein	A0A1P8VVR4	Streptococcus_phage	1.7e-124	90.0
WP_111685880.1\|1788928_1790848_+\|tail	phage tail protein	A0A1P8VVT1	Streptococcus_phage	5.2e-181	64.6
WP_063629043.1\|1790844_1791960_+	hyaluronoglucosaminidase	A7J2A8	Streptococcus_phage	1.7e-123	71.7
WP_111685861.1\|1791974_1793756_+	hypothetical protein	Q938J9	Temperate_phage	2.0e-73	42.8
WP_111685862.1\|1793764_1794193_+	DUF1617 family protein	Q938J8	Temperate_phage	3.7e-63	89.3
WP_111685863.1\|1794195_1794834_+	hypothetical protein	A3F662	Streptococcus_phage	1.2e-44	53.2
WP_111685864.1\|1794843_1795116_+	hypothetical protein	A7J2B2	Streptococcus_phage	1.6e-35	89.9
WP_003058873.1\|1795112_1795340_+\|holin	phage holin	A7J2B3	Streptococcus_phage	2.0e-31	100.0
WP_111685865.1\|1795455_1796673_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	3.7e-164	60.1
WP_002982304.1\|1797551_1798112_+	peroxiredoxin	NA	NA	NA	NA
1796951:1796976	attR	NA	NA	NA	NA
WP_023610722.1\|1798132_1799665_+	alkyl hydroperoxide reductase subunit F	A0A2I2L5E1	Orpheovirus	1.8e-43	37.5
WP_172451689.1\|1799722_1800988_-	imidazolonepropionase	NA	NA	NA	NA
WP_063632876.1\|1801279_1803310_+	urocanate hydratase	NA	NA	NA	NA
WP_003058706.1\|1803397_1804297_+	glutamate formimidoyltransferase	NA	NA	NA	NA
WP_023610734.1\|1804307_1804934_+	cyclodeaminase/cyclohydrolase family protein	NA	NA	NA	NA
WP_023610779.1\|1804951_1806625_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_023610736.1\|1806646_1807243_+	HutD family protein	NA	NA	NA	NA
WP_023610757.1\|1807462_1808806_+	APC family permease	NA	NA	NA	NA
WP_023610706.1\|1808816_1810358_+	histidine ammonia-lyase	A0A1V0S940	Catovirus	4.0e-99	43.6
WP_010922741.1\|1810543_1811530_+	formimidoylglutamase	NA	NA	NA	NA
WP_023610743.1\|1811567_1814642_-	AAA family ATPase	NA	NA	NA	NA
WP_002982262.1\|1814945_1815713_+	30S ribosomal protein S2	NA	NA	NA	NA
WP_085577423.1\|1815846_1816887_+	elongation factor Ts	NA	NA	NA	NA
WP_009880612.1\|1817053_1818949_-	M13 family metallopeptidase	A0A1V0SHG2	Klosneuvirus	2.3e-72	28.6
WP_023610760.1\|1819156_1820785_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_023610715.1\|1820851_1822876_-	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_002982243.1\|1823086_1823800_+	trehalose operon repressor	NA	NA	NA	NA
WP_023610754.1\|1824602_1825460_+	VOC family protein	NA	NA	NA	NA
WP_023610692.1\|1825501_1826233_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	3.3e-35	37.4
WP_021775544.1\|1826406_1827021_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A288TZV3	Enterococcus_phage	1.1e-52	56.7
WP_014407930.1\|1827035_1827530_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_023610759.1\|1827538_1828474_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_023610752.1\|1828502_1828649_-	hypothetical protein	NA	NA	NA	NA
WP_002992831.1\|1828830_1831029_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	2.6e-277	64.9
WP_011055088.1\|1831125_1832685_-	membrane protein	NA	NA	NA	NA
WP_002982199.1\|1833098_1833404_-	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_002982196.1\|1833415_1833835_-	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_002982194.1\|1833831_1834101_-	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_002982188.1\|1834213_1834612_-	transcriptional regulator Spx	NA	NA	NA	NA
WP_023610714.1\|1834902_1836039_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.1e-121	63.0
WP_023610745.1\|1836127_1837399_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_023610776.1\|1837467_1838028_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_002992186.1\|1838037_1838634_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_002991361.1\|1838635_1839856_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	2.7e-05	24.3
WP_023610727.1\|1839866_1841849_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
WP_023610769.1\|1841977_1844533_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	5.2e-43	23.3
WP_011889237.1\|1844519_1844726_-	YlbF family regulator	NA	NA	NA	NA
WP_023610766.1\|1844868_1845306_-	arginine repressor	NA	NA	NA	NA
WP_023610730.1\|1845596_1847288_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	6.4e-74	32.4
WP_002991370.1\|1847375_1847684_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage