CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483361	Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179 chromosome 1	3 crisprs	DEDDh,csa3,DinG,csm6,csn2,cas2,cas9,cas1,cas4,cas7,cas8c,cas5,cas3	0	9	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483361_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483361_1

941882-941974

Orphan

Consensus_repeat	Method
AGTAGACGAGGAGTCTGCTCAAGAGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483361_1

>merge|NZ_LS483361|1|941882-941974|CRISPRCasFinder
AGTAGACGAGGAGTCTGCTCAAGAGGACGCCTCAGATCCAACGCCTGAAGTTGACGAAGTGCCGGCAGTAGACGAGGAGCCTGCTCAAGAGGA

>NZ_LS483361|1|1|941882-941974|CRISPRCasFinder
AGTAGACGAGGAGTCTGCTCAAGAGGA	CGCCTCAGATCCAACGCCTGAAGTTGACGAAGTGCCGGC
AGTAGACGAGGAGCCTGCTCAAGAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483361.1\|WP_111716180.1\|931418_932297_+\|mevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NZ_LS483361.1\|WP_111716192.1\|938245_941590_+\|fibronectin-binding-protein	unknown	unknown	gnl\|CDD\|380076
NZ_LS483361.1\|WP_003061604.1\|949728_950328_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NZ_LS483361.1\|WP_111716204.1\|947686_948184_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NZ_LS483361.1\|WP_111716206.1\|950466_951210_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483361.1\|WP_111716177.1\|929471_931214_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LS483361.1\|WP_003054192.1\|948489_949719_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NZ_LS483361.1\|WP_003054200.1\|948203_948374_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483361.1\|WP_111716188.1\|934215_935208_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|235465
NZ_LS483361.1\|WP_111716185.1\|933215_934229_+\|phosphomevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NZ_LS483361.1\|WP_111715596.1\|937160_938114_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LS483361.1\|WP_111716172.1\|925261_927286_-\|bifunctional-metallophosphatase/5'-nucleotidase	unknown	unknown	gnl\|CDD\|277357
NZ_LS483361.1\|WP_111716199.1\|945367_946549_-\|hydroxymethylglutaryl-CoA-synthase	unknown	unknown	gnl\|CDD\|213655
NZ_LS483361.1\|WP_111716209.1\|951266_953366_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NZ_LS483361.1\|WP_111716182.1\|932278_933223_+\|diphosphomevalonate-decarboxylase	unknown	unknown	gnl\|CDD\|130307
NZ_LS483361.1\|WP_111716194.1\|942405_943950_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|368260
NZ_LS483361.1\|WP_111716197.1\|944109_945387_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	unknown	unknown	gnl\|CDD\|153082
NZ_LS483361.1\|WP_111716201.1\|946766_947606_+\|thymidylate-synthase	unknown	unknown	gnl\|CDD\|234984
NZ_LS483361.1\|WP_111716175.1\|927748_929470_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_LS483361.1\|WP_111716190.1\|935353_936880_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470

Protein	Function_ID	Function_description	E-value
NZ_LS483361.1\|WP_111716180.1\|931418_932297_+\|mevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	1.46583e-101
NZ_LS483361.1\|WP_111716192.1\|938245_941590_+\|fibronectin-binding-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	4.10142e-19
NZ_LS483361.1\|WP_003061604.1\|949728_950328_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	5.10795e-117
NZ_LS483361.1\|WP_111716204.1\|947686_948184_+\|dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	2.23672e-62
NZ_LS483361.1\|WP_111716177.1\|929471_931214_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.39558e-152
NZ_LS483361.1\|WP_003054192.1\|948489_949719_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NZ_LS483361.1\|WP_111716188.1\|934215_935208_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	3.69698e-163
NZ_LS483361.1\|WP_111716185.1\|933215_934229_+\|phosphomevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	9.75857e-82
NZ_LS483361.1\|WP_111715596.1\|937160_938114_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.90207e-54
NZ_LS483361.1\|WP_111716172.1\|925261_927286_-\|bifunctional-metallophosphatase/5'-nucleotidase	gnl\|CDD\|277357	cd07412, MPP_YhcR_N, Bacillus subtilis YhcR endonuclease and related proteins, N-terminal metallophosphatase domain. YhcR is a Bacillus subtilis sugar-nonspecific endonuclease. It cleaves endonucleolytically to yield nucleotide 3'-monophosphate products, similar to Staphylococcus aureus micrococcal nuclease. YhcR appears to be located in the cell wall, and is thought to be a substrate for a Bacillus subtilis sortase. YhcR is the major calcium-activated nuclease of B. subtilis. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.17069e-116
NZ_LS483361.1\|WP_111716199.1\|945367_946549_-\|hydroxymethylglutaryl-CoA-synthase	gnl\|CDD\|213655	TIGR01835, 3-hydroxy-3-methylglutaryl_CoA_synthase, 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade. This clade of hydroxymethylglutaryl-CoA (HMG-CoA) synthases is found in a limited spectrum of mostly gram-positive bacteria which make isopentenyl pyrophosphate (IPP) via the mevalonate pathway. This pathway is found primarily in eukaryotes and archaea, but the bacterial homologs are distinct, having aparrently diverged after being laterally transferred from an early eukaryote. HMG-CoA synthase is the first step in the pathway and joins acetyl-CoA with acetoacetyl-CoA with the release of one molecule of CoA. The Borellia sequence may have resulted from a separate lateral transfer event.	0
NZ_LS483361.1\|WP_111716209.1\|951266_953366_-\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NZ_LS483361.1\|WP_111716182.1\|932278_933223_+\|diphosphomevalonate-decarboxylase	gnl\|CDD\|130307	TIGR01240, Diphosphomevalonate_decarboxylase, diphosphomevalonate decarboxylase. This enzyme catalyzes the last step in the synthesis of isopentenyl diphosphate (IPP) in the mevalonate pathway. Alternate names: mevalonate diphosphate decarboxylase; pyrophosphomevalonate decarboxylase [Central intermediary metabolism, Other].	1.07251e-153
NZ_LS483361.1\|WP_111716194.1\|942405_943950_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	8.85195e-10
NZ_LS483361.1\|WP_111716197.1\|944109_945387_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	gnl\|CDD\|153082	cd00644, HMG-CoA_reductase_classII, Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class II, prokaryotic enzyme is a homodimer. Class II enzymes are found primarily in prokaryotes and Archaeoglobus fulgidus and are soluble as they lack the membrane region. Enzymes catalyze the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. Bacteria, such as Pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. Human and bacterial HMGR differ in their active site architecture.	0
NZ_LS483361.1\|WP_111716201.1\|946766_947606_+\|thymidylate-synthase	gnl\|CDD\|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	1.54373e-116
NZ_LS483361.1\|WP_111716175.1\|927748_929470_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	7.14571e-135
NZ_LS483361.1\|WP_111716190.1\|935353_936880_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	1.11365e-12

>NZ_LS483361.1|WP_111716192.1|938245_941590_+|fibronectin-binding-protein
MGTKSRKFKIEGETIVFEREKSRFSIRKNKCYGTCSVFLGLTILTLAMAGGNVKADSPVSAEEAPTTSTLVAPEGAAQHLPTESTAGYSLESDEEGLETDTEMAPASLEAQGATPRAIEGEVVAGQDVSDKLTTIKAEFEEVEESIDPNNGQHLYFESVFDIADDVKQGDYFYLSLSKEITPFGDDKSHQDQFESLHDGEEIIAVANYEENSNRIKYTFTDKITSKTNINGFIRLPLFIDRYAVPNSQNILPEVKIGKIVATASVNIDYANLDSKTFELNANVYSIITSVEDNKSEFEWTIYINPLQHRIDKTILRLFPYDGQNPEIKSAADFLHLDKSKLRLYSVPTDYKLPESFGVDYQSLNEVPLDNILQRYNNSYLINLDTKLSQGEAYVLKLRSLYNKNIKDISVTAELTSIEDTHGSIAKHEFEEGQAGAKSLEAVGFFVEKHIFKTVDELGNTIKEDVLIENSDSGKVGSEFSTEKSKRFPEYSLKEVMSTTGTKFSSTGEKVSNLYIKNKVQEVTYLYQRQIVTRGSFQEHHDYYDMEREFDGTILKRTKNTNLSYSGQMQSGKETEHYTTQKNEQDDYKFLTVTGAKNEPVYNNKGETSQGNFVANVKKEVTYEYEKVNQPGRFEDTHKYFINYVDANGQIIRTEEVNSLTNQYQEGMPEWDEYVAYPLEKDGFVFKTTSNDKLTNPGNFDKETKITRGSYIPGEMQHITYNYYKDVLLSGTVIATYGEFGTGQPLSDAVFATYGKADKELPNGAGQLNDDYVTVAKDIPGYHLVEQPENAKGKVSDGVTYVHYLYQKDKEPLGTVIVRHIEFGTGKELAPSEYATYDDVPADVPAGSTVAGTGYETKPAQIDGYDLVEVPENDYGNVVEGITRLTYVYKKQIITGQGEIIDFELESNGDESGQNEQPDEISEHGPLVELEYPSQEGMSGENAGTLEIEENSPIVELDYPSQEDMSGENAGTLEIEEGSPLVELEYPSQEGMSGENAGTVEIEESSPIVELDYPSQEGMSGENAGTVEVEEKAPIVEMDYPSQEGMSGENSGQQTIEEDTPTVTNEEKPVVKPVSSQPSKAELPATGERSETAVTVLGLALSALGLTFIRKRKQN
>NZ_LS483361.1|WP_111715596.1|937160_938114_-|IS30-family-transposase
MTYTHLTTTELVMIEAYYKEGITVSHICQSLKRSRQTIYKVIAYLKAGHTAYDYYKDYKDYKANKKRCGRRQTQLTQSEQDFIQRHLELNWSLDVVKGTYPDKIPCSMRTLYRLADRGIFKKDDLPWKGKRKSNGMVEKRGKQAFRRDIRERSEIYPDFDTEFGHLEGDTIVGKHHKSAVVTLVEKQSKAIITLQTNGRKASDIEQSLNRWLSQFPKHLFKSVTFDCGKEFSNWKTIANQHDIDIFFADPGCPGQRGLNEHSNGLLRRHGLPKQMDFNGIPQKYLSAIADKRNRIPRKSLNYRTPYQVFLSYVKCLA
>NZ_LS483361.1|WP_111716190.1|935353_936880_-|helix-turn-helix-domain-containing-protein
MLDYHLERKIMDRVTIVRLLCQYQQLTIHQICQQTSFSYKKVMTIIGELQEIYADFTVVHYDKSVITLRQDAKQQKEFLLHRLYQESLVLKALTFFLSDSQDYFDSFAQSAFISLATAYRVKQKCQHFLASVGLSIHKNHISGPEYRVRYLIALLQYRYGCNIYPLTNKDMNLVESFVLASNAQISQDSLSFRPESFQFFAILIALTWKRQTNHPNLPDTETFRDFKQLFSYDRLHTISQEVLTSDAWSLSETDIDYLFLIYLTLNTPLFKDQWTSKDIEQTLTIVTKKTPILHLILKFEQLLGPQITSSQPFLILMVFLMKQCFLNLQCLTPYQEASPFSARKEDPFFALVDDLISEWAQEVNLTLTLTPHRFTVQLIEMIKSQLPPIAIYVFANTITNLHTLTMILSQQFSSKIASIEGVNFLSEPLKQHRHRRKSLILAEHNCLPYLKTVYSEDDYVFVEVAYDAYELYQEDVFNAFHQLRQEQYQTFIASICDRHKRLKNHDTY
>NZ_LS483361.1|WP_111716188.1|934215_935208_+|type-2-isopentenyl-diphosphate-Delta-isomerase
MTNRKDDHIKYALKYQSPYNAFDDMELIHHSLPSYDVADIDLSTHFAGQDFEFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRLHEVAEGLKLATNIGLDKPVERGQQTVKEMNPLFLQVHVNVMQELLMPEGERVFQTWKQHLADYASQIRVPIILKEVGFGMDVSTIKIAHELGIQTFDISGRGGTSFAYIENQRGLERSYLNDWGQTTVQCLLNAQGLLDHVEILASGGVRHPLDMIKCLVLGARAVGLSRTVLELVEKYPVERVIDIVNGWKEDLKLIMCALDCRTIQDLRQVDYLLYGRLYQANH
>NZ_LS483361.1|WP_111716185.1|933215_934229_+|phosphomevalonate-kinase
MLNYRVQTGGKLYLTGEYAILEPGQLALIQFIPLMMTAEIGPSSHLQLASDMFDHKADMTPDASYGLIQATIKTFANYMGQSVEQLDPFSLSITGKLERDGKKFGIGSSGSVTLLTLKALSAYYQQPLSPELLFKLAAYTLLVQEDNGSMGDIACIAYQTLVAYTSFDRQQVSQWLSDMPLRDLLAKDWGYQIQIIEPALSCDFLVGWTKIPSISSQMIQQVKAKISPSFLTTSYELSQETIAALQSGHKETLKTSLTRASQLLRALDPAIYHPKLVTLVEACQGLDAVAKSSGSGGGDCGIALAFDRQAKETLINRWQTADIDLLYQERWGNHDES
>NZ_LS483361.1|WP_111716182.1|932278_933223_+|diphosphomevalonate-decarboxylase
MDPNVITVTSYANIAIIKYWGKEDQAKMIPSTSSISLTLENMFTTTSVSFLPDTASSDQFYINGCLQDDKEHAKISAIIDQFRKPNQPFVKVETQNNMPTAAGLSSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSASRSFFGPVAAWDKDSGNIYKVDTDLKMAMIMLVLNDAKKPISSRDGMKLCRETSTTFDEWIEKSAVDYQNMLTYLKANDFERVGQLAESNALAMHATTKTANPSFSYLTDDSYQAMEAVKQLRQEGFSCYFTMDAGPNVKVLCLEKDLETLATRFEKDYRIIVSKTKDLPDA
>NZ_LS483361.1|WP_111716180.1|931418_932297_+|mevalonate-kinase
MNEKIGYGKAHSKIILMGEHAVVYGYPAIALPLTDIEVVCHIFPADKPLTFDFYDTLSTAIYAALDHLQHLEEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVFSYFQKSLPDELLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIKIDLGAFLIIADTGVHGHTREAVNKVAQFEETNLPYLAKLGRLTEAVEKAITQKDNQAIGQLMTQAHSALKAIGVSIAKADQLVDAALKAGALGAKMSGGGLGGCMIALADTKEMAETISHKLQEEGAVNTWIQML
>NZ_LS483361.1|WP_111716177.1|929471_931214_+|ABC-transporter-ATP-binding-protein
MALFKRLLSEIKVAKAAFATGIGLLLLATAAGQIAPLLLKQLIDHYLTPLAKGKSIVLAHFEQLSWLYLALIIGSALLRYVSYRSLVYSSNKVVTQLRKQAFDVMQRLPISYFDHQPAGKIATRIVNDTETLRNQFYDNLLSQIIISMAQIIFIYGVMIYLNLRSGLLLLLVIPIFYGIQVLYKRLTDQPMKAFYDARSAVNTQVNETMNGVSIIQLFHQENHMLEDFNQQINQMKKADDKIIFADSVASWTLTELVKYTMISAILAFIGYQFLQGKPGITVGKLFIYLNYLTRLFDILGTMVRQLPNIQRSQATGSRLMALLDQELEEDNPKEIHIDKGNVSFNHVSFAYEEGKNVLTDITIEAKQGETIALVGHTGSGKSSIMNLLYRFYTPQSGMITVDGQDIQAYSRESLRSQMGIVLQDPYLFSGTIASNVTMGNQSYSDQEVIEALEKVGAGPMIGRLDKGIHEPVYEKGASYSSGERQLIAFARTLITNPKILILDEATSHIDTETEEIIQRAMEVLKQGRTTFIIAHRLSTIQSANTIFVLDKGRIVERGNHQELLAKGGIYAQLSKLQEKV
>NZ_LS483361.1|WP_111716175.1|927748_929470_+|ABC-transporter-ATP-binding-protein
MLSLMSRYIKQNKWTYIIIALTLFVYDASLIIPTKVIQSLIDAMFRYQLTQASLMSHVLVLLGATILSYATAYVWHLKLFQEAVHFKFDLQQRAFRKLVFMRTPFYEKFRSGDMMTRFSTDVEALMDFIGYGLMIILYAGGMIAFIIPTMFLISWQMSLIGMIPISIMMVITYFITKKQEVLVEDAREAISNLSDEVLETVEGIRVMRAYSKKDYMENHFVQKAEALADRWNRIAGYRGLYFPVYSVMIAISTLIILTVGLHFISKGEVSLGQVIALQLYLVSLVEPFAMLSDFILVYQTGRTSFNKINELIETGDDLEEDGHLKLESYDQIRLADYSFSYAKSSKPSLSAINLVLNKGETLGIVGKTGSGKTTLVRQLLRQYPVGQGQFYINGHHVLEYQRHALEEHIGYVPQEHVLFSKTVSENIAMGKEDATLDDILAAIATASFTDDLKGLSKGLDTKIGERGLSISGGQKQRISIARAFLSEPDLLILDDSLSAVDAKTETEIITHIQEERQGKTTIIVSHRLSAIQHADWVIVIDQGKIVEEGKPDQLLAQKGWYYEQYQRQQAQED
>NZ_LS483361.1|WP_111716172.1|925261_927286_-|bifunctional-metallophosphatase/5'-nucleotidase
MKKHLVLKSSVLSVFAGFSMLVTGVQADQVDVQLLGVNDFHGALDTTGSAYMPEGKVANAGTAAQLDAYMDDAETEFKQASPEGTSIRVQAGDMVGASPANSGLLQDEPTVKVFNKMGFEYSTLGNHEFDEGLAEFNRIMTGQAPAADSTINDITKNYEHEASKQTIVIANVVDKESNKIPYDWKPYAVKDVPVNDKSVKVGFIGIVTTEIPNLVLKQNYEQYKFLDAAETIVKYAKELQGQNVNAIVVLAHIPATSKDGVVDNEVATIMEKVNQLYPNHSVDIVFAGHNHQYTNGTVGKTRVVQAVSQGKAYADVRGTLDTDTNDFVATPEAKVIAVAPGVKTGSADIKAIVDQANEIVKTVTERKIGTASTSSTIPKMENNDKESPVGNLVTTAQLAIAKKTFPNVDFAMTNNGGIRADLVVKDDQTITWGAAQAVQPFGNILQVVQITGQQIYDVLNQQYDEGQKYFLQMSGLKYTYTDNEAKNPEVPFKVVKVYKDNGEELDLAANYTLVVNDFLYGGGDGFSVFKSAKLIGAINPDTEVFIEYIKDLEAAGKPVSATVKGVKTYVTSTLEGSTKTDDTGKHDIISRIFRDRAGNILSTEIVSDLVTPAVKADEKKLTTPKQAEELAAKSKTANASLPMAGSNQSSSTLMMILGFLTLGGAGLLKKKDRN
>NZ_LS483361.1|WP_111716194.1|942405_943950_-|helix-turn-helix-domain-containing-protein
MTFCSREVSKIQDYIEGKLTEQVTFLNALLDFQDIHLSQLATLVDAGEKKVADTLKDLALLYEDQLSWTIKGGQVQLETSILGNKLHYFYAIYQNSLFLQTLHFFLDPKQKDFSDFSQSQFVSTATAYRLKKKCLNFLKEVGLTIRHNQISGPEHRMRFLIALLHYRYGFPIYEFAKKDLDLVKDIIVTSNKTLNLAILENTPEEYQFFSYLVILSWYRHDYPLSDFCDHNLEHLKSIFIFDRVSTICSRVLEPKLGIQFSEREREYLFLAYCTTNNALYKDQWLVSDKKEMLQIVRLDTDIKYLLPHCEALFGSQISTSNFFTVACMFLMQNYLCGMQGLLPEGFFGHYHLDEEDHILLSIVTHLLDNWLKVLGIEEHNNTVACYLLTVHLRELIKLHLEPVPVYVFANNIADLSLLQTYLKLNFPTSVADIYGINILTSPCLESLNQKKGIILSDLRNRDYLKNLYQQQDHHFINFSMSFHALSQTVIAETIAKLRQENYQTFLNQLYSTLQ
>NZ_LS483361.1|WP_111716197.1|944109_945387_-|hydroxymethylglutaryl-CoA-reductase,-degradative
MTNMNLNWAGFSKKTFEERLQLIKQFELLTPEHLQALEKDYLLPIETANQLTENVLGRFALPFSIAPDFLINGVSYQVPFVTEEPSVVAAASFAAKLIKRSGGFASKVLKRQMIGQVALYDIDQVEEAKQTILANSDKLIAAANDAYPSIVKRGGGAREIRLEEKGDFLIFYLTVDTQEAMGANMVNTMMEALIPDLESLSKGQSLMAILSNYATESLVTASCQVDIRFLSRDKTEAQQLAKKMVLASQLAQADSYRAATHNKGIFNGIDAVVMATGNDWRAIEAGGHAYASRNGSYQGLSHWEFDQEQEVLLGQLTLPMPIASKGGSIGLNPTVSIAHDLLNQPDAKTLAQVIVSVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGAKEEEVAPLVTSLLADKPMNLEKASQHLAILRNA
>NZ_LS483361.1|WP_111716199.1|945367_946549_-|hydroxymethylglutaryl-CoA-synthase
MKIGIDKIGFATSQYVLKLDDLALARQTDPAKFSQGLLIEALSVTPVTEDIVTLAASAADQILTDEDKATIDMVILATESSVDQSKAAAIYVHHLMGIQPFARSFEVKEACYSATAALDYAKLHVAAKPESRVLVIASDIAKYGIDSAGESTQGAGSIAMLVTANPRILELHQDNLAQTRDIMDFWRPNYSTTPFVNGVYSTKQYLDSLETTWQAYQDKTGAQLTDFAAFCFHLPFPKLALKGLNKMMDESLPVEHTEHLLENFQASITYSKQIGNIYTGSLYLGLLSLLENSKTLQAGDRIGLFSYGSGAVSEIFSGQLVAGYEQMLMTDRQTILDQRHRLSVAEYEELFYEEAKLDKRGNASFNTYLTSKFALTEIKDNQRLYQINDKYES
>NZ_LS483361.1|WP_111716201.1|946766_947606_+|thymidylate-synthase
MTKADDIFKANIEKIMDEGVFSEQARPKYKDGRTANSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELLWIYQDQTNSLDVLENKYNVHYWNEWEVGQTRTIGQRYGAVVKKHDIISKLLKQLAENPWNRRNVISLWDYEAFEETEGLLPCAFQTMFDVRRVGKDLYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFVNNLHIYDNQFPQAKELLKRQPTDCQPKLVLNVPDGTNFFDIKPEDFELQDYEPVKPQLRFDLAI
>NZ_LS483361.1|WP_111716204.1|947686_948184_+|dihydrofolate-reductase
MTKEMIAIWAEDETGLIGVDGKLPWYLPRELQHFKETTLNQVILMGRVTFDGMNRRLLPNRQTLVMTRDVNYQVDGVLTMTSVEEVLDWYHAQEKTLYVIGGSKVLEAFDGYFNRVIKTVVHHQFEGDTYRPKLDLSRFKEESQTFYPKDANNPYDFTVTVLKHQ
>NZ_LS483361.1|WP_003054200.1|948203_948374_+|hypothetical-protein
MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGTLFLLNAFTNLVNSIHAFYGTLF
>NZ_LS483361.1|WP_003054192.1|948489_949719_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVLETA
>NZ_LS483361.1|WP_003061604.1|949728_950328_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTMLGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEYLTSRDNLRAVVSLVDLRHEPSKEDVQMYEFLKYYDIPVIIVATKADKIPRGKWNKHESMVKKTLGFDKTDRFIIFSSVDRVGIDEAWDTILEHL
>NZ_LS483361.1|WP_111716206.1|950466_951210_+|hypothetical-protein
MTRVAIGDPARKCLLWDRCSALCVFIIFLALLTMLFVIRYRNSSIEGIWKTASIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSEMILQVKNNKAHLSFRVQVEKAAFAERLASYHENELLKILKDNHLVIGELSQEEQQIIDSSMPAHHELEMILDQAFEKLASNIGGHYDRKTGSLSAIILNGNVNRILHTIDISELTTGHISLSKGITTPNGYFDYIKFGRKLELLGDEKIIFKKITEKSASGTS
>NZ_LS483361.1|WP_111716209.1|951266_953366_-|ATP-dependent-Clp-protease-ATP-binding-subunit
MTNYYDKDPFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGTEQPTAQGHQTKKDGILAKLGTNLTEEARQGKLDPVIGRNHEIQATAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILIGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGASDLERLKKISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGHQEDENTDQSAIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISEDAKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

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Crispr_ID: NZ_LS483361_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483361_2

1234708-1235272

TypeII

II-A

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	PILER-CR

8 spacers

csn2,cas2,cas9

The CRISPR arrays of NZ_LS483361_2

>merge|NZ_LS483361|2|1234708-1235272|CRISPRCasFinder,CRT,PILER-CR
GAATTGGGACCATTCAAAACAGCATAGCTCTAAAACCTAAAACGGCCAAGTTCATTGAGCTTCCTAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTGTGGTTGCCTTGGCTCAAATGAGTAAGTAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTGAAGCGAAGTGTTTATCGAGAAAGGATACGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTTTGCGAAAGTTACTCTATCATATTGTCGAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACATGCACGCTAACTGCCGCAGCACATTTGCTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACTGCTTGCCATCTGAGCCTTTATCGCCGTAAGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACCACTCTCGGTGTCGTCATCAAGATAGACGGTGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAACACACTCGATGCTTCACCCTACCGTGCAACCGTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483361|2|2|1234708-1235272|CRISPRCasFinder
GAATTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CTAAAACGGCCAAGTTCATTGAGCTTCCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGTGGTTGCCTTGGCTCAAATGAGTAAGTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGAAGCGAAGTGTTTATCGAGAAAGGATAC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TTTGCGAAAGTTACTCTATCATATTGTCGA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ATGCACGCTAACTGCCGCAGCACATTTGCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGCTTGCCATCTGAGCCTTTATCGCCGTAA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CACTCTCGGTGTCGTCATCAAGATAGACGGT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ACACTCGATGCTTCACCCTACCGTGCAACC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483361|2|1|1234708-1235272|CRT
GAATTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CTAAAACGGCCAAGTTCATTGAGCTTCCTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGTGGTTGCCTTGGCTCAAATGAGTAAGTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGAAGCGAAGTGTTTATCGAGAAAGGATAC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TTTGCGAAAGTTACTCTATCATATTGTCGA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ATGCACGCTAACTGCCGCAGCACATTTGCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGCTTGCCATCTGAGCCTTTATCGCCGTAA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CACTCTCGGTGTCGTCATCAAGATAGACGGT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ACACTCGATGCTTCACCCTACCGTGCAACC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

>NZ_LS483361|2|1|1234774-1235272|PILER-CR
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGTGGTTGCCTTGGCTCAAATGAGTAAGTA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGAAGCGAAGTGTTTATCGAGAAAGGATAC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TTTGCGAAAGTTACTCTATCATATTGTCGA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ATGCACGCTAACTGCCGCAGCACATTTGCT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	TGCTTGCCATCTGAGCCTTTATCGCCGTAA
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	CACTCTCGGTGTCGTCATCAAGATAGACGGT
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC	ACACTCGATGCTTCACCCTACCGTGCAACC
GTTTTGGGACCATTCAAAACAGCATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483361.1\|WP_011106805.1\|1236025_1236367_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_LS483361.1\|WP_111716669.1\|1227934_1228954_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NZ_LS483361.1\|WP_111716675.1\|1230422_1230719_-\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NZ_LS483361.1\|WP_111716695.1\|1245061_1245826_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_LS483361.1\|WP_111716672.1\|1229063_1230233_-\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_LS483361.1\|WP_111716667.1\|1227302_1227728_-\|PTS-mannose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NZ_LS483361.1\|WP_111716697.1\|1245825_1246578_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NZ_LS483361.1\|WP_111716686.1\|1235373_1236036_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NZ_LS483361.1\|WP_111716700.1\|1246588_1247719_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_LS483361.1\|WP_003051133.1\|1225967_1226777_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226238
NZ_LS483361.1\|WP_111716693.1\|1244432_1245062_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_LS483361.1\|WP_111716691.1\|1242798_1244271_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_LS483361.1\|WP_111716684.1\|1234132_1234591_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_LS483361.1\|WP_111716702.1\|1247780_1248422_-\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483361.1\|WP_111716689.1\|1237232_1241348_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_LS483361.1\|WP_003051135.1\|1226792_1227284_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NZ_LS483361.1\|WP_111716678.1\|1230955_1231606_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_LS483361.1\|WP_111716680.1\|1231618_1232056_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_LS483361.1\|WP_111716682.1\|1232230_1234063_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_LS483361.1\|WP_111716705.1\|1248544_1249900_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670

Protein	Function_ID	Function_description	E-value
NZ_LS483361.1\|WP_011106805.1\|1236025_1236367_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.69845e-58
NZ_LS483361.1\|WP_111716669.1\|1227934_1228954_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	6.14541e-101
NZ_LS483361.1\|WP_111716675.1\|1230422_1230719_-\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	0.00200364
NZ_LS483361.1\|WP_111716695.1\|1245061_1245826_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.61605e-127
NZ_LS483361.1\|WP_111716672.1\|1229063_1230233_-\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	4.20839e-78
NZ_LS483361.1\|WP_111716667.1\|1227302_1227728_-\|PTS-mannose-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	3.12581e-29
NZ_LS483361.1\|WP_111716697.1\|1245825_1246578_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	9.24897e-99
NZ_LS483361.1\|WP_111716686.1\|1235373_1236036_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	7.20395e-122
NZ_LS483361.1\|WP_111716700.1\|1246588_1247719_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_LS483361.1\|WP_003051133.1\|1225967_1226777_-\|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC	gnl\|CDD\|226238	COG3715, ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism].	7.13101e-76
NZ_LS483361.1\|WP_111716693.1\|1244432_1245062_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	5.40033e-75
NZ_LS483361.1\|WP_111716691.1\|1242798_1244271_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.12869e-32
NZ_LS483361.1\|WP_111716684.1\|1234132_1234591_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.1429e-75
NZ_LS483361.1\|WP_111716689.1\|1237232_1241348_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_LS483361.1\|WP_003051135.1\|1226792_1227284_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	1.55198e-54
NZ_LS483361.1\|WP_111716678.1\|1230955_1231606_-\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	3.94734e-32
NZ_LS483361.1\|WP_111716680.1\|1231618_1232056_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	3.71391e-85
NZ_LS483361.1\|WP_111716682.1\|1232230_1234063_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_LS483361.1\|WP_111716705.1\|1248544_1249900_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0

>NZ_LS483361.1|WP_111716684.1|1234132_1234591_-|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGLVGEVLRRIERRGFTFDRLELRQASPELLAKHYEALVTKPFYPELEAYMTSGPVLIGVLSGNRVISSWRTMMGVTNPKDALPGTIRGDFAQAPGDDGGIFNVVHGSDSRDSARREIALWFNQAELDSSAIFPKDNQ
>NZ_LS483361.1|WP_111716682.1|1232230_1234063_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDGDMIEVSNPSEFPDPTRVASIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDDDAKK
>NZ_LS483361.1|WP_111716680.1|1231618_1232056_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METKDDLKKRIGDLSYEVTQHAATERPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPQEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDEK
>NZ_LS483361.1|WP_111716678.1|1230955_1231606_-|HD-domain-containing-protein
MTEKEAQLLAQAEAWVKEKLAADASGHDFWHVNRVCRLAKIIAQEEEGDVFICQLAALLHDMADDKLNADPKKARQDILTWLAGHDVSQKQSDQVMTIIDTISFKGGHGKPLTNLEAKIVQDADRLDAIGAIGIARCMAYSGHTGRLIHDPDRLPRETMTVEEYRKDGTAIMHFHEKLLTLKERMNTAYGRQLAEHRHQVLVSYLDEFYAEWDGLR
>NZ_LS483361.1|WP_111716675.1|1230422_1230719_-|bacteriocin-immunity-protein
MSRLNWFSGANERQQQASLLIKDLVADLKQSGGKEPLQKVLLSFDEELKRGESSIPFILSRMTVAVSTVLKEHQITLSAKESAQLDDLYALLQIRYGY
>NZ_LS483361.1|WP_111716672.1|1229063_1230233_-|DUF2974-domain-containing-protein
MATLLDYIKTNGNRDYHSLALNELDVAVINEIGYLAFDELVADDNHLEATIKLSQLPLLQTREIKGAPYDFLNTKERLDLFQMMCQSKRFSELTLSHYINDINTEFEKQFAAMVFRLPSIDYTQLVFRGTDDSLIGWKEDFKLTYMREIPAHRSAIDYLKSYHTYYPNQKLVLSGHSKGGNLALYAASFVPKNVQASLKDIYLFDSPGLIKEFLTHPGYQAIRRRLVVIKPQDAIIGVMLYCDVPEKIVQSQSYGLFQHQMVNWQITPNAQFKRVPKRSALSYDLEETFKDWTNQLSKQDLKLLCDTFFDCLASTGITSLNAFSIDDKAFLTLMRVISSLQSIDHEKKKVMVKSLDQLMVTYGSYRRRDISENIHNHLQQLLALTKGIK
>NZ_LS483361.1|WP_111716669.1|1227934_1228954_-|YeiH-family-putative-sulfate-export-transporter
MSTYLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHNSDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTIATALLVAYGLQKWLGLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEIAKAISVIFLFNILAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAIIPITLGLSLYRAKKEHEIVTEEGFSLSKSFPPFILFFLLASLITTLMTSFGVSADVFHSLKELSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLGMQFALGIW
>NZ_LS483361.1|WP_111716667.1|1227302_1227728_-|PTS-mannose-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQSLEIIDAYVDDSDYTSQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMASGKDNIFLITNSNLATLLSVMFLNPDEALTKDEIVTVINESQVQLVDLSPATDSEDDFFD
>NZ_LS483361.1|WP_003051135.1|1226792_1227284_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEESIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELASLPNLDVFNQVLPSNTKVHLSQLVN
>NZ_LS483361.1|WP_003051133.1|1225967_1226777_-|PTS-mannose/fructose/sorbose/N-acetylgalactosamine-transporter-subunit-IIC
MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDMKVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGMLAAFVVMFLKNVFMNIFAPMVDKAAEANHQGQLVMLHYGTWIIYYLIIASISFIGILVGSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYLKLPAVAVAALGAVICVISSQRDLELDAITKGAFSNQTSFDSKESEEEDFFA
>NZ_LS483361.1|WP_111716686.1|1235373_1236036_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLDEPIPLRGGTILVLEDVCVFSKIVQHCYQYEEDSELKFFDHKMKAIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEEYFLITKNMV
>NZ_LS483361.1|WP_011106805.1|1236025_1236367_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPHKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NZ_LS483361.1|WP_111716689.1|1237232_1241348_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWSVITDDYKVPSKKMKVLGNTGKQTIKKNLLGALLFDSGETAEATRLKRTARRRYTRRKNRIRYLQEIFANEMAKVDDSFFHRLEESFLVEEDKKHERHPIFGNIADEVAYHEKYPTIYHLRKKLADSTDKADLHLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINKSGVDAKAILSARLSKSRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFSDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLTKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEEFYPFLKENREKIEKILTFRIPYYVGPLARGDSRFAWMTRKSDEAITPWNFEEVVDKGASAEAFIKKMTNFDEYLPTEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPEFLSGKQKEAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKKYANLFDDKVMKQLKRRHYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLINDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQTVKIVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKVLTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNVKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTERDENHKTIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGSALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKRFFYSNIMNFFKIEITLANGEIRKRPLIEVNEETGEIVWNKEKDFATIRKVLSMPQVNIVKKTEVQTGALTNESIYARGSFDKLISRKHRFESSKYGGFGSPTVTYSVLVVAKSKVQDGKVKKIKTGKELIGITLLDKLVFEKNPLKFIEDKGYGNVQIDKCIKLPKYSLFEFENGTRRMLASVMANNNSRGDLQKANEMFLPAKLVTLLYHAHKIESSKELEHEAYILDHYNDLYQLLSYIERFASLYVDVEKNISKVKELFSNIESYSISEICTSVIDLLTLTATGAPADFKFLGTTIPRKRYGSPQSILSSTLIHQSITGLYETRIDLSQLGGD
>NZ_LS483361.1|WP_111716691.1|1242798_1244271_-|IS1182-family-transposase
MLHKEKPDYNRNQYGFYTLDQLVPDEHFLRQVEAVIDFNFIYDLVEDTYSSDNGRPSLDPVILVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLTLDDKVPHFTTYGKNYSRRFQEKGLIESIFTHILGLCINTGLIDPTEIFIDGTHIKAAANNRKFINREVEKQAKFMSEQLEIEINRDREKHGKKPLGPAKELGPVAKKISTTDPESGWFHKGDHKEVFAYSAQVACDKYGWALAYSVEAGNIHDSQAFPALFAKLEPLKPQFIIADSGYKIPSIAKFLIDKEITPVLPYIRPRGKKDLLRPKEFIYDEHFDCVICPEHQALTYRTTTREGYREYKSDPVICANCPLLSVCTTSKNHQKVVTRHIWKDYLEQCEDIRHQRGMKELYQHRKETIERLFGTAKEYHNLRYTREKGKSKMEDKVGLTLACLNLKKLVKRMAGEPFYFVQMRWFKRGNSHFYLKTLKKTNTKSMFVFNLNKRFENACF
>NZ_LS483361.1|WP_111716693.1|1244432_1245062_-|TIGR01906-family-membrane-protein
MVENIKLFCSWLWLLALAILMTIYSAWLWYPLEVEYLKLEQVVFMSKDAILHNYNGLLNYLTNPFETSLTFASFRSSTDGLKHFADVKWLFHLTQVIFLGLLYTTVKDFKQRFKTKSFWSIQRPLMIAALFPLMIGLMASVIGFENFFILFHKVLFVRDSNWLFDPLKDPVIWILPEVFFLHCFLFFMTVYEIILWSLVGLARWQRPKI
>NZ_LS483361.1|WP_111716695.1|1245061_1245826_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGLPYLLVTNNTTRTPEMVQDMLSKQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYDMLATATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPIFIGKPNAIIMNKSLEVLGVKRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPVQPDHVLSSLDEWEL
>NZ_LS483361.1|WP_111716697.1|1245825_1246578_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYREDIKLPFELCDVKSDIKFPLLLDYCLTVSGRQSAQLGRSNDYLLEQYGLIWIVTDYEATIHRLPRFKETITIETQAMSYNKFFCYRQFYIYDQEGQLLVDILAYFALLNPETRKVASIPEDLVAPFETDFVKKLRRAPKMHLLEKPIDQDYRVRYFDIDMNGHVNNSKYLDWMYDVLGYEFLKAHEPLRMTLKYVKEVSPGGQITSSYQLDQLTSYHQITTAGQLNAQAMIEWRAIKQTESETD
>NZ_LS483361.1|WP_111716700.1|1246588_1247719_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLEALIQEFESYDIHDLKTLYIGGGTPTAITAAQLEYLLSHLERNLNLSYLEEFTIEANPGDLTPDKIEVLKQSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIYALPGQTLAQVKENVAKALALDIPHLSLYSLILEHHTVFMNKTRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEERYGTIVRDLQDQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NZ_LS483361.1|WP_111716702.1|1247780_1248422_-|hypothetical-protein
MTKQQIEKLADLLPPFAAKLYLDMIPEFQEGYVSYVYQTQKEDTQNRRIKQLTKSFARLLDTPSFYVMPLSAQVVRQLLRDEEIACHSLSSVGAIQAFEAAVEDEKEVLQLLRNGSRLALLVLEEANEIVHMDLGILTKGEQKVISPAMLTAIEEHLLAATERNALQLTVTVEQGAARTFYQAHGFHQKADDLVFKPTDGKLICQMVKDLFKA
>NZ_LS483361.1|WP_111716705.1|1248544_1249900_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIGGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGSDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLNGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRRSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Crispr_ID: NZ_LS483361_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483361_3

1565020-1565192

TypeI

I-C

Consensus_repeat	Method
CCTATTTCAATCCACTCACCCGTGAAGGGTGAGAC	CRISPRCasFinder
AAACCTATTTCAATCCACTCACCCGTGAAGGGTGAGAC	PILER-CR

2 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_LS483361_3

>merge|NZ_LS483361|3|1565020-1565192|CRISPRCasFinder,PILER-CR
TAGGATGCAATCCACTCACCCGCGAAGGGTGAGACGATGGACTACATCGAGACGGAATTTGATGTAAAACCTATTTCAATCCACTCACCCGTGAAGGGTGAGACACTGCAATCACTTTTTGGCATTCCCAAAGTAACCCTATTTCAATCCACTCACCCGTGAAGGGTGAGACT

>NZ_LS483361|3|3|1565020-1565191|CRISPRCasFinder
TAGGATGCAATCCACTCACCCGCGAAGGGTGAGAC	GATGGACTACATCGAGACGGAATTTGATGTAAAA
CCTATTTCAATCCACTCACCCGTGAAGGGTGAGAC	ACTGCAATCACTTTTTGGCATTCCCAAAGTAAC
CCTATTTCAATCCACTCACCCGTGAAGGGTGAGAC

>NZ_LS483361|3|2|1565027-1565192|PILER-CR
CAATCCACTCACCCGCGAAGGGTGAGACGATGGACTACAT	CGAGACGGAATTTGATGTAAAACCTATTTC
AATCCACTCACCCGTGAAGGGTGAGACACTGCAATCACTT	TTTGGCATTCCCAAAGTAACCCTATTTCAA
TCCACTCACCCGTGAAGGGTGAGACT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483361.1\|WP_111717187.1\|1570946_1573373_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_LS483361.1\|WP_111717191.1\|1576290_1576854_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379082
NZ_LS483361.1\|WP_111717173.1\|1562913_1563846_-\|magnesium-transporter-CorA-family-protein	unknown	unknown	gnl\|CDD\|213361
NZ_LS483361.1\|WP_111717167.1\|1560201_1561308_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NZ_LS483361.1\|WP_111717182.1\|1567341_1568190_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_LS483361.1\|WP_003051927.1\|1555116_1555590_+\|arginine-repressor	unknown	unknown	gnl\|CDD\|224355
NZ_LS483361.1\|WP_111717185.1\|1570086_1570815_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_LS483361.1\|WP_111717163.1\|1557643_1559377_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225519
NZ_LS483361.1\|WP_111717183.1\|1568194_1570087_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187773
NZ_LS483361.1\|WP_111717171.1\|1561983_1562694_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	unknown	unknown	gnl\|CDD\|223856
NZ_LS483361.1\|WP_111717159.1\|1555752_1556469_-\|B3/4-domain-containing-protein	unknown	unknown	gnl\|CDD\|225917
NZ_LS483361.1\|WP_111717176.1\|1563937_1564897_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_LS483361.1\|WP_111717180.1\|1566665_1567340_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|224385
NZ_LS483361.1\|WP_003044506.1\|1565339_1565633_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
NZ_LS483361.1\|WP_111717189.1\|1573640_1576289_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NZ_LS483361.1\|WP_111717193.1\|1576850_1577441_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NZ_LS483361.1\|WP_111717165.1\|1559373_1560114_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|227095
NZ_LS483361.1\|WP_111717161.1\|1556491_1557571_-\|MmcQ/YjbR-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|225197
NZ_LS483361.1\|WP_111717178.1\|1565643_1566669_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_LS483361.1\|WP_111717169.1\|1561347_1561971_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264

Protein	Function_ID	Function_description	E-value
NZ_LS483361.1\|WP_111717187.1\|1570946_1573373_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	8.16524e-153
NZ_LS483361.1\|WP_111717191.1\|1576290_1576854_-\|AAA-family-ATPase	gnl\|CDD\|379082	pfam13238, AAA_18, AAA domain.	0.00107363
NZ_LS483361.1\|WP_111717173.1\|1562913_1563846_-\|magnesium-transporter-CorA-family-protein	gnl\|CDD\|213361	cd12827, EcCorA_ZntB-like_u2, uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family. A uncharacterized subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB (EcCorA-ZntB_like) family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes.The EcCorA-ZntB-like family includes the Mg2+ transporters Escherichia coli and Salmonella typhimurium CorAs, which can also transport Co2+, and Ni2+. Structures of the intracellular domain of EcCorA-ZntB-like family members, Vibrio parahaemolyticus and Salmonella typhimurium ZntB, form funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport through Salmonella typhimurium CorA. Natural variants such as GVN and GIN, such as occur in some ZntB family proteins, may be associated with the transport of different divalent cations, such as zinc and cadmium. The functional diversity of MIT transporters may also be due to minor structural differences regulating gating, substrate selection, and transport.	2.3266e-79
NZ_LS483361.1\|WP_111717167.1\|1560201_1561308_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.08505e-166
NZ_LS483361.1\|WP_111717182.1\|1567341_1568190_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	2.99634e-158
NZ_LS483361.1\|WP_003051927.1\|1555116_1555590_+\|arginine-repressor	gnl\|CDD\|224355	COG1438, ArgR, Arginine repressor [Transcription].	3.23269e-65
NZ_LS483361.1\|WP_111717185.1\|1570086_1570815_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	1.39822e-111
NZ_LS483361.1\|WP_111717163.1\|1557643_1559377_-\|sensor-histidine-kinase	gnl\|CDD\|225519	COG2972, COG2972, Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms].	3.52763e-63
NZ_LS483361.1\|WP_111717183.1\|1568194_1570087_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187773	cd09642, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csd1 family.	0
NZ_LS483361.1\|WP_111717171.1\|1561983_1562694_-\|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2	gnl\|CDD\|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	3.86116e-41
NZ_LS483361.1\|WP_111717159.1\|1555752_1556469_-\|B3/4-domain-containing-protein	gnl\|CDD\|225917	COG3382, COG3382, Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only].	1.40242e-103
NZ_LS483361.1\|WP_111717176.1\|1563937_1564897_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.20629e-57
NZ_LS483361.1\|WP_111717180.1\|1566665_1567340_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|224385	COG1468, COG1468, CRISPR-associated protein Cas4 (RecB family exonuclease) [Defense mechanisms].	8.47999e-40
NZ_LS483361.1\|WP_003044506.1\|1565339_1565633_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	2.32373e-34
NZ_LS483361.1\|WP_111717189.1\|1573640_1576289_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NZ_LS483361.1\|WP_111717193.1\|1576850_1577441_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	5.62353e-34
NZ_LS483361.1\|WP_111717165.1\|1559373_1560114_-\|response-regulator-transcription-factor	gnl\|CDD\|227095	COG4753, COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain [Signal transduction mechanisms].	8.6319e-85
NZ_LS483361.1\|WP_111717161.1\|1556491_1557571_-\|MmcQ/YjbR-family-DNA-binding-protein	gnl\|CDD\|225197	COG2315, MmcQ, Uncharacterized protein conserved in bacteria [Function unknown].	5.43329e-32
NZ_LS483361.1\|WP_111717178.1\|1565643_1566669_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_LS483361.1\|WP_111717169.1\|1561347_1561971_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	8.58888e-36

>NZ_LS483361.1|WP_111717176.1|1563937_1564897_-|Gfo/Idh/MocA-family-oxidoreductase
MAKVRYGIVSTAQVAPRFIEGVRLAGNGEVVAVSSRSLDKAKAFATAHQLPKAYGSLDDMLLDVSIDAIYVASINQDHFPAAKKALLAGKHVLVEKPFTLTAAQAEELFALAQERGLFLMEAQKAVFIPMTQRLKGLIAAGELGDIVSVSSTTAYPNIDHVTWFRDLEKGGGTVHFMAPYALSYLPYLFDADIVSASGVAHFPKGQSDSQSKLILALSNGVLVDIFLTTHLSLPHELVIYGTKGRLEIPHFWKTTHATLVRPDGSRSVIEATMSSDFEAEAHHVSQMILEGQLTSPVMTKSLTLSGVGLIEKLYRSWGK
>NZ_LS483361.1|WP_111717173.1|1562913_1563846_-|magnesium-transporter-CorA-family-protein
MPILPKASSAITLINLDQLTEHDQEALVSEGLIDAEVFDYAKDKNETSFMEENKEKLTIVFQILDRQEEAYHPNHIPRVIPITLFLNDQSLYILGHDHSLALIEEVFPDLDESRSPRHLVFQLLTAFTKQYVPLMDEIAQQRDKLIEALRQKANKTNLESLANLQSGTVYILMGSKQNEQMLAELKNMPGQQDLEEDEAEQLRDTIIEARQLSNMCDLNTRVLKEISSSYNNVLSNNLNNNVTSLTIFSIGISIIAMVTSFYGMNVKLPFAKVDSVWFWIVLTTSLVALLIMVVMYWYVHKRNRNASKRI
>NZ_LS483361.1|WP_111717171.1|1561983_1562694_-|thiol-disulfide-oxidoreductase-associated-membrane-protein-CcdA2
MTLSIVLIASVFAAGLLSFFSPCIFPVLPVYLGILLDADDSRTMTIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGIHQVGLITIKRLQFQKSLTFHNDKNRNGLLNVFILGLTFSFGWTPCVGPVLSSVLALVASGGSGAWQGGLLMIVYTLGLGIPFLLLSFASGFVLKHFNKLKPHMLLLKKVGGVLIIIMGILLMTGTLNNLAQLFG
>NZ_LS483361.1|WP_111717169.1|1561347_1561971_-|TlpA-family-protein-disulfide-reductase
MKKGLLVTTGLACLGLLTACSAQDNMAKKEMTQDKMSVATKTNDKMSTSKDKSMMTDKSSDKKMTNEGPRAPDFELKSVDGKTYRLSDLKGKKVYLKFWASWCSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYRDLPVLLDPDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKADIQKNLKAIH
>NZ_LS483361.1|WP_111717167.1|1560201_1561308_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MEHKWKLLLFIVGVVVLIGGASILIQRGQAKAFSQGKPQLPAKKVKSTKLDPNVPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIHQTGHAETVEVTYDANRVSLKELLLHFFRIIDPTSVNKQGNDRGSQYRTGIYYTDKADLAVIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPVIDESKYPKPSAAEIKAKLSADEYRVTQKNETERAFSNRYWDSFEAGIYVDVVTGEPLFSSKDKFESGCGWPSFSRPISPDVIRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKDQGGLRYCINSLAITFIPKADMEAKGYGYLLSSVE
>NZ_LS483361.1|WP_111717165.1|1559373_1560114_-|response-regulator-transcription-factor
MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQSPKEVSELAMAIQGQLADSRLTLKSLAHQLGFSPNYLSVLIKKELGLPFQDYLVQERLKKAKLLLLTSDLKIYEIAEQVGFEDMNYFSQRFKQLVGMTPSQYKKGGRA
>NZ_LS483361.1|WP_111717163.1|1557643_1559377_-|sensor-histidine-kinase
MRRYPLLVQLISYVFVMVLALITTLGLLYYQTSSRNIRQLIERDTRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFASQIHQEDDKQVLQLMEMVLATNSDLQAAVLVTKDGRTVSTNPQLTMKTSSDMMAETWYKAAIDRQAMPVLTPARQLSLSSKKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVYHPKKSVYSSSREMAAMKPYLAIKNGYAKDKSSFVYQRVIPNSQWTLIGVASLDQLHRVQRQIFWSFLGMGLLACLICGLTTILVLRKWIRPIQQLQQVILAIQKGNRQLRAQETGSPELTDLAHQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWMAEFNDSKRVVEVTKSLAKYFRLALNQGNDYIRLADELDHVSQYLFIQKQRYGDKLTYDVQGLDAYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSETAQHLILTVWDNGKGIEASALTNSQSLLTRGGVGLKNVDQRLKLQYGEAYQMIIQSQSDQFTEIQLSLPKRHELMADDTQENE
>NZ_LS483361.1|WP_111717161.1|1556491_1557571_-|MmcQ/YjbR-family-DNA-binding-protein
MSLATDYFSRQTPIVEKLMAYGFEKRDNGYFYNERFMEEEFEAQLRIDKAGNIWDRVIDCDLEEDYLPLQQAAWQGTYSGQVRAAYLELLERLSVACFEATPFQSMQANRLAKRITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPERLVGQTCEVMTVKVNPKDLHQLLQQEGIYPAYHMSKNNWVSVVLDDKVTDDQLLGLVIQSRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYMTAPVKSIRYACQVLETNIPNQGYRKNPNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAAVRGPRRLSPQLIAFLKEKEYLKGNN
>NZ_LS483361.1|WP_111717159.1|1555752_1556469_-|B3/4-domain-containing-protein
MVQFVADQSFWELFPDAKLGVILLKDVQNQGESPEDVKQLLADSHELAKAYLTADNFSDNQVVQVYRKAYQQFKTKKGARSSIEALLKRVANGQTIPSINPLVDIYNAASLRFGLPVGAEDSDSFTGDLRLTVTDGGDDFYLIGDADNNPTLPNELCYKDDIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQHALDFIEGSAKMYLHAITSLHVLDKDNPHVPLFTEN
>NZ_LS483361.1|WP_003051927.1|1555116_1555590_+|arginine-repressor
MNKKETRHQLIRSLISETTIHTQQELQERLRKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKVVQNQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
>NZ_LS483361.1|WP_003044506.1|1565339_1565633_-|CRISPR-associated-endonuclease-Cas2
MMVLVTYDVNTETSAGRKRLRHVAKLCVDYGQRVQNSVFECSVTPAEFVDIKHRLTQIIDGETDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL
>NZ_LS483361.1|WP_111717178.1|1565643_1566669_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGIVCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREESLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTRLFEAVNEELLWALEMVQAADNKDSLRGIEGQAANQYFRIFNDLVLTDKKTFQFQGRSKRPPLDCVNTLLSFGYSLLTFECQSALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVKENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLESYPPFMV
>NZ_LS483361.1|WP_111717180.1|1566665_1567340_-|CRISPR-associated-protein-Cas4
MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGEILHTKADNPYIKEKRKDLLVSRAMSISSGELGLSGIMDVVEFYKDDQGVSLRGKRGKWLPKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLGCHINEGCLYYHSVNQRVTVEMTSALRQEVRELATEMHEVYQSQMLPKAEYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMISEEMTL
>NZ_LS483361.1|WP_111717182.1|1567341_1568190_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSIKRKIRNRLQDMGKPIFVQANERIEDDFRSLEKRFSQHFTAKTPDTEIEEKANALWFDVRAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNESGRSSDTMGTKHFVDYGVYVLKGSINAYFAEKTGFSQEDADAIKEVLVSLFENDASSARPEGSMRVREVFWFTHSSKLGNISSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTVEILEGL
>NZ_LS483361.1|WP_111717183.1|1568194_1570087_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MDFFTSLLKTYEKAELADLVDHQKRDNEPVLLPIYHTSLKSNGKNIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSNPAPHPLVDKFAYYSAEVDQSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTSILDSLIGPDYQNNQLKITFCDVTGKEKLIDLSACFLEFSIDQFQGFKNESISTFKALHQSYISFVEANRENLGICNISGREEQLTDKHRGLMGNAKVISVSNKREAYKGRFREREDVFSVGYETSEKIHLMIKYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPTFDDGLEEDDDDTSPVIALASEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLDKWQEKYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQVQKLVTSLIDGKPMPQSIVKKLGSNIKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRSYLFGRLLAIFELIETLRYGLDGTDSDRITNAERYWTAYTGQPTKLMMLLENKIKPYEEPLKLNRRGSWKKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNTEVTESEE
>NZ_LS483361.1|WP_111717185.1|1570086_1570815_-|type-I-C-CRISPR-associated-protein-Cas5
MYRSRDFYVRVSGQRALFTNPATKGGSERASYSVPTRQALNGIVDAIYYKPTFTNIVTEVKIINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFVWNEDRKDLNSDRLPAKHEAIMGRSICKGGRRDVFLGTRECVGLVDDISQEEYEAAVSYYNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVIMFKAQSECDIVNTLSSYAFKAPEEIKSVNDEYMEYDAMEKGEN
>NZ_LS483361.1|WP_111717187.1|1570946_1573373_-|CRISPR-associated-helicase-Cas3'
MMTKETLAHYQKKTEQESEKKQSLDEHLWHVACSSRQEASIIGQGDVLFLIGLYHDLGKSDRAFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFNEMVGYVISAHHGMYDLCYYSDDAEYYSFNKFKNRINRDLDGYHYHEDIKGYALKLEEKLCDYGYKDLRELIDKAFDNYRQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDTVNAYGLKVSPMDKIERSFLKHSYLAAIEQKYASFGRPNNQLNIIRTEIAERVRERGKRDSKGIYRLDLPTGAGKTNLSMRYAFHQLVHQDKSRFFYITPFLSVLEQNASEIRKVTGDRGVLEHHSNVVKQANEDDDDKNNLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANLRRFSSLINSVVILDEVQSLPIEVTSLFNLTMNFLNKVMNTTIVLCTATQPAYDSSEIDHRICYGGNLGESAEIVELTIEEKQIFSRTELRKFDDNNQKVHLTDVINLILGEENSVLTIFNTKKTVNSCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICISTQLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLTEIKAKKEGTESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNISIYDYLSLNTYQTVNKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGVAKKKLAYLEELGAPHFLSVEDYQTIKSLLKELQPFTVNVRENDPLLEATKSYLNGQILVLTSEYYDTKRGVKYDSASFYF
>NZ_LS483361.1|WP_111717189.1|1573640_1576289_-|valine--tRNA-ligase
MTELSPKYNPAEVEAGRYQKWLAADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARKATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYKAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDSEDFNRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTFDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFNSNINYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELFRLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIVEMKKLVG
>NZ_LS483361.1|WP_111717191.1|1576290_1576854_-|AAA-family-ATPase
MNLIIIGAQASGKMTIGQEIAKQTGMTLFHNHDSIDFVLRFMPWSQESTALIERLRFNFFETFAKNGQEMIFTIVIDFNDPNDVAFLEKIQAVFQSYDQEVLFVELETDVNERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPSEPPKTLTHYQKINNTHLTAAETAQLIIQKMTHIKEN
>NZ_LS483361.1|WP_111717193.1|1576850_1577441_-|GNAT-family-N-acetyltransferase
MIVKMLEAYSGKALPKVETERLVLRQRKLEDAEDIFAFAKLAEVSYPAGFPPVKSLADEITYLQDIYPANLEKEGLPSGYGITLKGDDKVIGSIDFNHRRADDVFEIGYLLHPDYWGQGIVPEAAAALIEIGFTLIDLHKIELGCYDYNKQSQAVARKLGFTLEANVRDRKDVQGRRCGDMRFGLLRSEWEAWKRK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448824	Streptococcus phage Javan637, complete genome	15668-15697	0	1.0
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK449002	Streptococcus phage Javan642, complete genome	15623-15652	0	1.0
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK449003	Streptococcus phage Javan648, complete genome	15623-15652	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448960	Streptococcus phage Javan492, complete genome	7957-7986	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448762	Streptococcus phage Javan447, complete genome	8083-8112	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448795	Streptococcus phage Javan527, complete genome	13640-13669	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448791	Streptococcus phage Javan517, complete genome	7024-7053	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	NC_004587	Streptococcus prophage 315.4, complete genome	7119-7148	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	8389-8418	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448977	Streptococcus phage Javan530, complete genome	7024-7053	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448793	Streptococcus phage Javan523, complete genome	8244-8273	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448788	Streptococcus phage Javan511, complete genome	7024-7053	0	1.0
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448954	Streptococcus phage Javan476, complete genome	8038-8067	0	1.0
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448858	Streptococcus phage Javan166, complete genome	16919-16948	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448862	Streptococcus phage Javan178, complete genome	12156-12185	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448970	Streptococcus phage Javan516, complete genome	17188-17217	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448854	Streptococcus phage Javan146, complete genome	16404-16433	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448694	Streptococcus phage Javan179, complete genome	15361-15390	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448957	Streptococcus phage Javan484, complete genome	16608-16637	1	0.967
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448790	Streptococcus phage Javan515, complete genome	18535-18564	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448798	Streptococcus phage Javan533, complete genome	29976-30005	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	NC_028700	Streptococcus phage T12, complete genome	29829-29858	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448790	Streptococcus phage Javan515, complete genome	29745-29774	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448783	Streptococcus phage Javan503, complete genome	28882-28911	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448967	Streptococcus phage Javan510, complete genome	29977-30006	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448856	Streptococcus phage Javan158, complete genome	8411-8440	1	0.967
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	NC_004588	Streptococcus prophage 315.5, complete genome	30126-30155	1	0.967
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448790	Streptococcus phage Javan515, complete genome	8370-8399	1	0.967
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK448683	Streptococcus phage Javan149, complete genome	9848-9877	1	0.967
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	NC_004585	Streptococcus prophage 315.2, complete genome	15785-15814	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448965	Streptococcus phage Javan506, complete genome	14832-14861	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448955	Streptococcus phage Javan478, complete genome	15424-15453	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448966	Streptococcus phage Javan508, complete genome	15640-15669	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448795	Streptococcus phage Javan527, complete genome	19679-19708	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448791	Streptococcus phage Javan517, complete genome	12155-12184	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448959	Streptococcus phage Javan488, complete genome	14832-14861	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448672	Streptococcus phage Javan117, complete genome	11557-11586	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	NC_004587	Streptococcus prophage 315.4, complete genome	12250-12279	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448945	Streptococcus phage Javan454, complete genome	15048-15077	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	13520-13549	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448849	Streptococcus phage Javan128, complete genome	11106-11135	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448772	Streptococcus phage Javan483, complete genome	15655-15684	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448962	Streptococcus phage Javan496, complete genome	6432-6461	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448977	Streptococcus phage Javan530, complete genome	12155-12184	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448949	Streptococcus phage Javan460, complete genome	15492-15521	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448783	Streptococcus phage Javan503, complete genome	13071-13100	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448788	Streptococcus phage Javan511, complete genome	12155-12184	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK449010	Streptococcus phage Javan90, complete genome	18079-18108	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448798	Streptococcus phage Javan533, complete genome	18862-18891	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448681	Streptococcus phage Javan141, complete genome	18454-18483	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	NC_028700	Streptococcus phage T12, complete genome	18713-18742	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448967	Streptococcus phage Javan510, complete genome	18863-18892	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448833	Streptococcus phage Javan87, complete genome	18079-18108	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	MK448683	Streptococcus phage Javan149, complete genome	20992-21021	2	0.933
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	NC_004588	Streptococcus prophage 315.5, complete genome	19012-19041	2	0.933
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK449010	Streptococcus phage Javan90, complete genome	29240-29269	2	0.933
NZ_LS483361_2	2.6\|1235074\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235074-1235103	30	MK448833	Streptococcus phage Javan87, complete genome	29240-29269	2	0.933
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MK449012	Streptococcus phage Javan94, complete genome	6815-6844	2	0.933
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK449010	Streptococcus phage Javan90, complete genome	13493-13522	3	0.9
NZ_LS483361_2	2.2\|1234810\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234810-1234839	30	MK448833	Streptococcus phage Javan87, complete genome	13493-13522	3	0.9
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448960	Streptococcus phage Javan492, complete genome	7957-7990	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448762	Streptococcus phage Javan447, complete genome	8083-8116	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448795	Streptococcus phage Javan527, complete genome	13640-13673	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448791	Streptococcus phage Javan517, complete genome	7024-7057	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NC_004587	Streptococcus prophage 315.4, complete genome	7119-7152	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	8389-8422	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448977	Streptococcus phage Javan530, complete genome	7024-7057	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448793	Streptococcus phage Javan523, complete genome	8244-8277	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448788	Streptococcus phage Javan511, complete genome	7024-7057	3	0.912
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448954	Streptococcus phage Javan476, complete genome	8038-8071	3	0.912
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	JX409894	Streptococcus phage LYGO9, complete genome	39418-39447	3	0.9
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448860	Streptococcus phage Javan172, complete genome	11295-11324	3	0.9
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448672	Streptococcus phage Javan117, complete genome	9540-9569	3	0.9
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448790	Streptococcus phage Javan515, complete genome	8370-8403	4	0.882
NZ_LS483361_3	3.2\|1565124\|33\|NZ_LS483361\|CRISPRCasFinder	1565124-1565156	33	MK448860	Streptococcus phage Javan172, complete genome	11292-11324	4	0.879
NZ_LS483361_3	3.2\|1565124\|33\|NZ_LS483361\|CRISPRCasFinder	1565124-1565156	33	MK448672	Streptococcus phage Javan117, complete genome	9537-9569	4	0.879
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK448683	Streptococcus phage Javan149, complete genome	9848-9881	5	0.853
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448675	Streptococcus phage Javan129, complete genome	14051-14080	5	0.833
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448681	Streptococcus phage Javan141, complete genome	10012-10041	5	0.833
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448676	Streptococcus phage Javan131, complete genome	16420-16449	5	0.833
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NZ_KY000033	Agrobacterium rhizogenes strain 26-59 plasmid pRi_26-59, complete sequence	30890-30919	6	0.8
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NZ_CP019703	Agrobacterium rhizogenes strain K599 (NCPPB2659) plasmid pRi2659, complete sequence	177592-177621	6	0.8
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NC_010841	Agrobacterium rhizogenes plasmid pRi2659, complete sequence	30896-30925	6	0.8
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NC_002575	Agrobacterium rhizogenes plasmid pRi1724 DNA, complete sequence	59735-59764	6	0.8
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NZ_KY000038	Agrobacterium rhizogenes strain 1724 plasmid pRi_1724, complete sequence	109440-109469	6	0.8
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	NZ_CP030355	Novosphingobium sp. P6W plasmid pP6W2, complete sequence	52281-52310	6	0.8
NZ_LS483361_2	2.5\|1235008\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235008-1235037	30	NZ_CP017887	Pseudomonas frederiksbergensis strain ERDD5:01 plasmid unnamed1, complete sequence	279305-279334	6	0.8
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	MK449012	Streptococcus phage Javan94, complete genome	6815-6848	6	0.824
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NZ_CP010270	Paenibacillus polymyxa strain Sb3-1 plasmid pSb31l, complete sequence	33720-33749	7	0.767
NZ_LS483361_2	2.7\|1235140\|31\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235140-1235170	31	NZ_CP011809	Pandoraea faecigallinarum strain DSM 23572 plasmid pPF72-2, complete sequence	28200-28230	7	0.774
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	MG602477	Bacillus phage BCP01, complete genome	38363-38392	7	0.767
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	KX495186	Bacillus phage PK16, complete genome	139956-139985	7	0.767
NZ_LS483361_3	3.4\|1565137\|30\|NZ_LS483361\|PILER-CR	1565137-1565166	30	MK448694	Streptococcus phage Javan179, complete genome	12890-12919	7	0.767
NZ_LS483361_2	2.3\|1234876\|30\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1234876-1234905	30	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	1262360-1262389	8	0.733
NZ_LS483361_3	3.3\|1565067\|30\|NZ_LS483361\|PILER-CR	1565067-1565096	30	AP013460	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18	28882-28911	8	0.733
NZ_LS483361_2	2.7\|1235140\|31\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235140-1235170	31	NZ_CP019033	Lactobacillus fermentum strain SNUV175 plasmid pSNU175-4, complete sequence	9042-9072	9	0.71
NZ_LS483361_2	2.7\|1235140\|31\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235140-1235170	31	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	786583-786613	9	0.71
NZ_LS483361_2	2.7\|1235140\|31\|NZ_LS483361\|CRISPRCasFinder,CRT,PILER-CR	1235140-1235170	31	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	933163-933193	9	0.71
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1807845-1807878	10	0.706
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	748588-748621	10	0.706
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	823066-823099	10	0.706
NZ_LS483361_3	3.1\|1565055\|34\|NZ_LS483361\|CRISPRCasFinder	1565055-1565088	34	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	246821-246854	10	0.706

1. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448824 (Streptococcus phage Javan637, complete genome) position: , mismatch: 0, identity: 1.0

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtggttgccttggctcaaatgagtaagta	Protospacer
******************************

2. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK449002 (Streptococcus phage Javan642, complete genome) position: , mismatch: 0, identity: 1.0

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtggttgccttggctcaaatgagtaagta	Protospacer
******************************

3. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK449003 (Streptococcus phage Javan648, complete genome) position: , mismatch: 0, identity: 1.0

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtggttgccttggctcaaatgagtaagta	Protospacer
******************************

4. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

5. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

6. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

7. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

8. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

9. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

10. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

11. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

12. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

13. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 0, identity: 1.0

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacggaatttgatgt	Protospacer
******************************

14. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448858 (Streptococcus phage Javan166, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgccttggctcaaatgagtaagta	Protospacer
**.***************************

15. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448862 (Streptococcus phage Javan178, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgaggttgccttggctcaaatgagtaagta	Protospacer
** ***************************

16. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgccttggctcaaatgagtaagta	Protospacer
**.***************************

17. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtggttgccttagctcaaatgagtaagta	Protospacer
************.*****************

18. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgaggttgccttggctcaaatgagtaagta	Protospacer
** ***************************

19. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.967

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgccttggctcaaatgagtaagta	Protospacer
**.***************************

20. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 1, identity: 0.967

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacatttgct	Protospacer
**************.***************

21. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

22. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

23. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

24. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

25. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

26. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448856 (Streptococcus phage Javan158, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

27. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 1, identity: 0.967

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttgccatctgaacctttatcgccgtaa	Protospacer
**************.***************

28. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 1, identity: 0.967

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagacagaatttgatgt	Protospacer
******************.***********

29. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 1, identity: 0.967

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactatatcgagacggaatttgatgt	Protospacer
*********.********************

30. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcagttgccttggctcaaatgagtaagta	Protospacer
**..**************************

31. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448965 (Streptococcus phage Javan506, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtgattgccttggctcaaaggagtaagta	Protospacer
****.*************** *********

32. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

33. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcagttgccttggctcaaatgagtaagta	Protospacer
**..**************************

34. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

35. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

36. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtgattgccttggctcaaaggagtaagta	Protospacer
****.*************** *********

37. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

38. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

39. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

40. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

41. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448849 (Streptococcus phage Javan128, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

42. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcagttgccttggctcaaatgagtaagta	Protospacer
**..**************************

43. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtgattgccttggctcaaaggagtaagta	Protospacer
****.*************** *********

44. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

45. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448949 (Streptococcus phage Javan460, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgtgattgccttggctcaaaggagtaagta	Protospacer
****.*************** *********

46. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448783 (Streptococcus phage Javan503, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

47. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 2, identity: 0.933

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tgcggttgtcttggctcaaatgagtaagta	Protospacer
**.*****.*********************

48. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

49. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448798 (Streptococcus phage Javan533, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

50. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

51. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

52. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448967 (Streptococcus phage Javan510, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

53. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

54. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

55. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_004588 (Streptococcus prophage 315.5, complete genome) position: , mismatch: 2, identity: 0.933

atgcacgctaactgccgcagcacatttgct	CRISPR spacer
atgcacgctaactgtcgcagcacgtttgct	Protospacer
**************.********.******

56. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 2, identity: 0.933

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttaccatctgagcctttatccccgtaa	Protospacer
*****.***************** ******

57. spacer 2.6|1235074|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 2, identity: 0.933

tgcttgccatctgagcctttatcgccgtaa	CRISPR spacer
tgcttaccatctgagcctttatccccgtaa	Protospacer
*****.***************** ******

58. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 2, identity: 0.933

gatggactacatcgagacggaatttgatgt	CRISPR spacer
aatggactacatcgagacagaatttgatgt	Protospacer
.*****************.***********

59. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 3, identity: 0.9

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tacggttgtcttggctcaaatgagtaagta	Protospacer
*..*****.*********************

60. spacer 2.2|1234810|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 3, identity: 0.9

tgtggttgccttggctcaaatgagtaagta	CRISPR spacer
tacggttgtcttggctcaaatgagtaagta	Protospacer
*..*****.*********************

61. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

62. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

63. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

64. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

65. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

66. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

67. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

68. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

69. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

70. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 3, identity: 0.912

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacggaatttgatgtatgg	Protospacer
******************************* ..

71. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 3, identity: 0.9

gatggactacatcgagacggaatttgatgt	CRISPR spacer
aatggaatacatcgaaacggaatttgatgt	Protospacer
.***** ********.**************

72. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 3, identity: 0.9

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gctgcaatcactttttggcattcccagagc	Protospacer
.*************************.**.

73. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 3, identity: 0.9

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gctgcaatcactttttggcattcccagagc	Protospacer
.*************************.**.

74. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 4, identity: 0.882

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactacatcgagacagaatttgatgtatgg	Protospacer
******************.************ ..

75. spacer 3.2|1565124|33|NZ_LS483361|CRISPRCasFinder matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 4, identity: 0.879

actgcaatcactttttggcattcccaaagtaac	CRISPR spacer
gctgcaatcactttttggcattcccagagcaat	Protospacer
.*************************.**.**.

76. spacer 3.2|1565124|33|NZ_LS483361|CRISPRCasFinder matches to MK448672 (Streptococcus phage Javan117, complete genome) position: , mismatch: 4, identity: 0.879

actgcaatcactttttggcattcccaaagtaac	CRISPR spacer
gctgcaatcactttttggcattcccagagcaat	Protospacer
.*************************.**.**.

77. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 5, identity: 0.853

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
gatggactatatcgagacggaatttgatgttttg	Protospacer
*********.********************   .

78. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448675 (Streptococcus phage Javan129, complete genome) position: , mismatch: 5, identity: 0.833

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gttgcaataactttttggcattcccagagc	Protospacer
..****** *****************.**.

79. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 5, identity: 0.833

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gttgcaataactttttggcattcccagagc	Protospacer
..****** *****************.**.

80. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448676 (Streptococcus phage Javan131, complete genome) position: , mismatch: 5, identity: 0.833

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gttgcaataactttttggcattcccagagc	Protospacer
..****** *****************.**.

81. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY000033 (Agrobacterium rhizogenes strain 26-59 plasmid pRi_26-59, complete sequence) position: , mismatch: 6, identity: 0.8

--tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gccgaggc--tgtgtttatcgaaaaaggatac	Protospacer
  .**.**   ***********.*********

82. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019703 (Agrobacterium rhizogenes strain K599 (NCPPB2659) plasmid pRi2659, complete sequence) position: , mismatch: 6, identity: 0.8

--tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gccgaggc--tgtgtttatcgaaaaaggatac	Protospacer
  .**.**   ***********.*********

83. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_010841 (Agrobacterium rhizogenes plasmid pRi2659, complete sequence) position: , mismatch: 6, identity: 0.8

--tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gccgaggc--tgtgtttatcgaaaaaggatac	Protospacer
  .**.**   ***********.*********

84. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NC_002575 (Agrobacterium rhizogenes plasmid pRi1724 DNA, complete sequence) position: , mismatch: 6, identity: 0.8

--tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gccgaggc--tgtgtttatcgaaaaaggatac	Protospacer
  .**.**   ***********.*********

85. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY000038 (Agrobacterium rhizogenes strain 1724 plasmid pRi_1724, complete sequence) position: , mismatch: 6, identity: 0.8

--tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gccgaggc--tgtgtttatcgaaaaaggatac	Protospacer
  .**.**   ***********.*********

86. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030355 (Novosphingobium sp. P6W plasmid pP6W2, complete sequence) position: , mismatch: 6, identity: 0.8

atgcacgctaactgccgcagcacat-ttgct	CRISPR spacer
cggaacgctaactgccgcaggacatagtgc-	Protospacer
  * **************** ****  ***

87. spacer 2.5|1235008|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017887 (Pseudomonas frederiksbergensis strain ERDD5:01 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

atgcac-gctaactgccgcagcacatttgct	CRISPR spacer
-tgttctgctaactggcgcagcacaattgca	Protospacer
 **. * ******** ********* ****

88. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to MK449012 (Streptococcus phage Javan94, complete genome) position: , mismatch: 6, identity: 0.824

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
aatggactacatcgagacagaatttgatgtgttg	Protospacer
.*****************.***********.  .

89. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010270 (Paenibacillus polymyxa strain Sb3-1 plasmid pSb31l, complete sequence) position: , mismatch: 7, identity: 0.767

tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
ttgaatgaaatgttgatcgagaaaggatat	Protospacer
* .*..***.**** **************.

90. spacer 2.7|1235140|31|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011809 (Pandoraea faecigallinarum strain DSM 23572 plasmid pPF72-2, complete sequence) position: , mismatch: 7, identity: 0.774

cactctcggtgtcgtcatcaagatagacggt	CRISPR spacer
cacggagcgtgttgtcatcaagatcgacggt	Protospacer
***     ****.*********** ******

91. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to MG602477 (Bacillus phage BCP01, complete genome) position: , mismatch: 7, identity: 0.767

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagaaggagcgagcttt	Protospacer
***************** ***..  * * *

92. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to KX495186 (Bacillus phage PK16, complete genome) position: , mismatch: 7, identity: 0.767

gatggactacatcgagacggaatttgatgt	CRISPR spacer
gatggactacatcgagaaggagcgagcttt	Protospacer
***************** ***..  * * *

93. spacer 3.4|1565137|30|NZ_LS483361|PILER-CR matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 7, identity: 0.767

actgcaatcactttttggcattcccaaagt	CRISPR spacer
gccactataactttttggcattcccagagc	Protospacer
.*..* ** *****************.**.

94. spacer 2.3|1234876|30|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 8, identity: 0.733

tgaagcgaagtgtttatcgagaaaggatac	CRISPR spacer
gcgcgcgaagtgtttatcgagcagggattt	Protospacer
  . ***************** *.**** .

95. spacer 3.3|1565067|30|NZ_LS483361|PILER-CR matches to AP013460 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18) position: , mismatch: 8, identity: 0.733

gatggactacatcgagacggaatttgatgt	CRISPR spacer
tatggactaccacgagacggaattaagagc	Protospacer
 *********  ************ .. *.

96. spacer 2.7|1235140|31|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019033 (Lactobacillus fermentum strain SNUV175 plasmid pSNU175-4, complete sequence) position: , mismatch: 9, identity: 0.71

cactctcggtgtcgtcatcaagatagacggt	CRISPR spacer
tcgcctcggtttcgtcatctagatagacccg	Protospacer
.  .****** ******** ********

97. spacer 2.7|1235140|31|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 9, identity: 0.71

cactctcggtgtcgtcatcaagatagacggt	CRISPR spacer
gcttgccggtggcgtcatcaatatagacgag	Protospacer
  .* .***** ********* *******.

98. spacer 2.7|1235140|31|NZ_LS483361|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.71

cactctcggtgtcgtcatcaagatagacggt	CRISPR spacer
gcttgccggtggcgtcatcaatatagacgag	Protospacer
  .* .***** ********* *******.

99. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
agctgaggtgatccagacggaatttgatgcaaaa	Protospacer
... **    *** ***************.****

100. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
agctgaggtgatccagacggaatttgatgcaaaa	Protospacer
... **    *** ***************.****

101. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 10, identity: 0.706

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
agctgaggtgatccagacggaatttgatgcaaaa	Protospacer
... **    *** ***************.****

102. spacer 3.1|1565055|34|NZ_LS483361|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 10, identity: 0.706

gatggactacatcgagacggaatttgatgtaaaa	CRISPR spacer
agctgaggtgatccagacggaatttgatgcaaaa	Protospacer
... **    *** ***************.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

40125 : 49951

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111714666.1\|40125_43851_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	2.9e-34	25.5
WP_111714669.1\|43969_45421_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-58	34.0
WP_111714671.1\|45573_46602_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	5.6e-65	43.4
WP_111714673.1\|46594_47149_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.9e-23	34.1
WP_111714676.1\|47199_48744_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.7e-76	48.1
WP_111714679.1\|48823_49951_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	3.4e-07	28.1

DBSCAN-SWA_2

143136 : 215928

Streptococcus_phage(23.08%)

holin,bacteriocin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111714825.1\|143136_144114_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_111714827.1\|144100_144973_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_111714829.1\|145115_146249_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_111714832.1\|146396_147617_-	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
WP_111714834.1\|148017_149676_+	SpaH/EbpB family LPXTG-anchored major pilin	NA	NA	NA	NA
WP_111714837.1\|149758_150709_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_111714840.1\|150710_151592_+	class C sortase	NA	NA	NA	NA
WP_111714842.1\|151575_152433_+	class C sortase	NA	NA	NA	NA
WP_172454451.1\|152501_157634_+	fibrinogen-binding adhesin SdrG C-terminal domain-containing protein	NA	NA	NA	NA
WP_003060730.1\|157751_158429_-	PAS domain-containing protein	NA	NA	NA	NA
WP_111714847.1\|158607_158967_+	RidA family protein	NA	NA	NA	NA
WP_003060913.1\|159004_160024_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_111714849.1\|160323_161586_-	toxic anion resistance protein	M1PLC8	Streptococcus_phage	1.7e-148	68.8
WP_003055205.1\|161598_162480_-	hypothetical protein	M1PFV6	Streptococcus_phage	2.2e-25	34.7
WP_003060354.1\|162908_164201_+	adenylosuccinate synthase	G5CQQ4	Megavirus	1.1e-70	36.5
WP_164714876.1\|164520_165564_+	BMP family protein	A0A0A7DN02	Lactobacillus_phage	1.4e-63	40.0
WP_111714852.1\|165767_166541_-	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_111714855.1\|166665_167412_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_111714857.1\|167427_168408_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_003049344.1\|168686_169007_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_111714860.1\|169034_169343_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_111714862.1\|169352_170657_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_111714865.1\|170933_173351_+	glycyl radical protein	Q66LZ4	Escherichia_phage	3.6e-09	52.8
WP_065957278.1\|173473_174433_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_111714868.1\|174558_176079_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	2.5e-255	91.7
WP_065956946.1\|176231_176690_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_111717877.1\|176709_177021_+	PTS fructose-like transporter subunit IIB	NA	NA	NA	NA
WP_111714870.1\|177035_178133_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_111714872.1\|178339_180685_+	formate C-acetyltransferase	A0A2K8HKE5	Bacteriophage	7.2e-07	52.9
WP_111714875.1\|180706_181492_+	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_003049351.1\|181512_182181_+	fructose-6-phosphate aldolase	E3SKN5	Synechococcus_phage	3.7e-25	34.3
WP_015016577.1\|182222_183311_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_003049355.1\|183510_183810_+	hypothetical protein	NA	NA	NA	NA
WP_003059612.1\|183882_184392_-	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	2.5e-37	52.9
WP_111714877.1\|184565_185117_+	hypothetical protein	NA	NA	NA	NA
WP_111714880.1\|185222_186248_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_111714883.1\|186519_186744_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_111714886.1\|186766_187087_+	role in replication	NA	NA	NA	NA
WP_111714888.1\|189130_189523_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_111714890.1\|189798_190719_+	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111714893.1\|190732_193198_+	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_111714895.1\|193476_193920_+	hypothetical protein	NA	NA	NA	NA
WP_111714898.1\|195561_196023_+\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
WP_003059606.1\|196161_196389_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014611948.1\|196390_196909_-	hypothetical protein	NA	NA	NA	NA
WP_111714900.1\|197015_198470_-	FAD/NAD(P)-binding protein	NA	NA	NA	NA
WP_111714902.1\|200188_200809_-	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_111714905.1\|200885_201482_+	hypothetical protein	NA	NA	NA	NA
WP_111714908.1\|201491_202142_+	Maf family protein	NA	NA	NA	NA
WP_111714910.1\|202270_202573_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_164714875.1\|203983_204391_-	DNA topology modulation protein	A0A097BYE2	Leuconostoc_phage	1.2e-26	45.9
WP_111714913.1\|205282_205909_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.8e-13	24.0
WP_111714915.1\|205892_206696_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	4.6e-06	25.8
WP_111714918.1\|206707_207529_-	ABC transporter permease	NA	NA	NA	NA
WP_111714920.1\|207525_208503_-	ABC transporter permease	NA	NA	NA	NA
WP_111714923.1\|208615_210244_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111714926.1\|211708_212998_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_111714928.1\|213960_215136_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	1.2e-31	33.2
WP_003060590.1\|215259_215616_+	hypothetical protein	NA	NA	NA	NA
WP_080504454.1\|215781_215928_-\|holin	putative holin-like toxin	NA	NA	NA	NA

DBSCAN-SWA_3

293529 : 346243

Streptococcus_phage(33.33%)

holin,integrase,tRNA,transposase

attL 285897:285913|attR 310775:310791

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
285897:285913	attL	NA	NA	NA	NA
WP_111715051.1\|293529_294873_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	3.8e-53	30.5
WP_003061211.1\|294865_295267_+	Mini-ribonuclease 3	NA	NA	NA	NA
WP_111715057.1\|296824_297610_+	hypothetical protein	NA	NA	NA	NA
WP_003059560.1\|297657_298404_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_003049554.1\|298407_298926_+	NYN domain-containing protein	NA	NA	NA	NA
WP_111715060.1\|299025_299886_+	DegV family protein	NA	NA	NA	NA
WP_111715062.1\|300019_300718_+	hypothetical protein	NA	NA	NA	NA
WP_011285176.1\|300714_300921_+	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	2.3e-10	56.1
WP_002982710.1\|301138_301585_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_002982716.1\|301605_301998_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_105152547.1\|302134_303289_-\|integrase	site-specific integrase	Q938N9	Temperate_phage	2.1e-44	33.2
WP_027973157.1\|303342_303861_-	helix-turn-helix domain-containing protein	W6LMS6	Streptococcus_phage	9.6e-05	38.7
WP_001287945.1\|304013_304298_+	hypothetical protein	NA	NA	NA	NA
WP_024383381.1\|304842_305130_+	DnaD domain protein	NA	NA	NA	NA
WP_111715065.1\|305144_305435_+	hypothetical protein	NA	NA	NA	NA
WP_024383345.1\|305427_305790_+	hypothetical protein	NA	NA	NA	NA
WP_024394922.1\|305789_306146_+	hypothetical protein	NA	NA	NA	NA
WP_111715068.1\|306658_307806_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-49	42.0
WP_024391379.1\|308715_309330_+	CadD family cadmium resistance transporter	NA	NA	NA	NA
WP_111715073.1\|309341_309680_+	Cd(II)/Zn(II)-sensing metalloregulatory transcriptional regulator CadX	E4ZFI8	Streptococcus_phage	4.5e-11	34.3
WP_111715079.1\|310515_312465_+	transcription antiterminator	NA	NA	NA	NA
310775:310791	attR	NA	NA	NA	NA
WP_111715081.1\|312466_312925_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_111715084.1\|314259_314544_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_111715086.1\|314545_315385_+	class II fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_111715089.1\|315384_316062_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_111715092.1\|316073_316595_+	YjbQ family protein	NA	NA	NA	NA
WP_111715095.1\|316841_317657_+	HAD family phosphatase	NA	NA	NA	NA
WP_003057148.1\|323228_323711_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_111715097.1\|323941_325291_-	aspartate kinase	NA	NA	NA	NA
WP_003054840.1\|325436_326186_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_111715100.1\|326175_326943_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_111715102.1\|326929_327403_+	ECF transporter S component	NA	NA	NA	NA
WP_111715105.1\|327413_327977_+	TIGR01440 family protein	NA	NA	NA	NA
WP_003061406.1\|328039_328885_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_111715108.1\|329271_330675_+	alpha-amylase	NA	NA	NA	NA
WP_111715110.1\|330930_332304_+	alpha-amylase	NA	NA	NA	NA
WP_111715113.1\|332511_333795_+	trigger factor	NA	NA	NA	NA
WP_111715115.1\|334008_334575_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_111715118.1\|334857_336462_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.1e-138	46.4
WP_111715121.1\|336537_338298_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	1.6e-64	31.2
WP_111715124.1\|338294_339023_+	LytTR family transcriptional regulator DNA-binding domain-containing protein	NA	NA	NA	NA
WP_111715126.1\|339200_340655_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	2.4e-255	91.7
WP_111715129.1\|340715_341165_+\|holin	antiholin-like murein hydrolase modulator LrgA	NA	NA	NA	NA
WP_111715131.1\|341182_341890_+\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_111715134.1\|342049_342976_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_111715137.1\|343320_344202_+	fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_002982870.1\|344744_344933_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_111715139.1\|345109_346243_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

405476 : 482898

103

Streptococcus_phage(52.17%)

portal,capsid,tail,transposase,head,protease,terminase,integrase,tRNA

attL 415272:415294|attR 463487:463509

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111715251.1\|405476_406370_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_111715253.1\|406635_407169_+	DUF177 domain-containing protein	NA	NA	NA	NA
WP_003049736.1\|407438_408125_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.3e-30	33.5
WP_111715255.1\|408130_409630_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.9e-24	29.4
WP_111714946.1\|409853_410987_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_003049740.1\|411160_411655_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_111715260.1\|411638_412817_+	DnaD domain protein	NA	NA	NA	NA
WP_111715262.1\|412817_413720_+	primosomal protein DnaI	S5MU12	Brevibacillus_phage	2.3e-30	32.2
WP_111715265.1\|413782_415093_+	ribosome biogenesis GTPase Der	NA	NA	NA	NA
415272:415294	attL	NA	NA	NA	NA
WP_111715267.1\|415430_416597_-\|integrase	tyrosine-type recombinase/integrase	C5J953	Streptococcus_phage	4.3e-77	43.3
WP_111715270.1\|416773_417667_-	hypothetical protein	A0A1I9LJQ0	Stx_converting_phage	2.8e-68	47.5
WP_111717887.1\|417702_418467_-	helix-turn-helix transcriptional regulator	J7KJ52	Streptococcus_phage	1.5e-91	67.3
WP_111715273.1\|418819_419113_+	ImmA/IrrE family metallo-endopeptidase	A0A1X9I661	Streptococcus_phage	1.3e-35	76.7
WP_164714868.1\|419096_419267_-	hypothetical protein	NA	NA	NA	NA
WP_111715276.1\|419324_419483_+	hypothetical protein	J7KH24	Streptococcus_phage	2.0e-22	96.2
WP_001008979.1\|419581_420223_-	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_111715278.1\|420272_420482_+	hypothetical protein	A0A097PAQ9	Streptococcus_pyogenes_phage	3.7e-32	98.6
WP_111715281.1\|420470_420857_-	hypothetical protein	A0A097PAT1	Streptococcus_pyogenes_phage	8.0e-65	98.4
WP_111715284.1\|420930_421137_+	helix-turn-helix transcriptional regulator	A0A1S5SFQ0	Streptococcus_phage	1.2e-14	57.4
WP_111715287.1\|421161_421923_+	phage antirepressor KilAC domain-containing protein	L0P8P6	Lactobacillus_phage	9.6e-70	52.9
WP_164714867.1\|421935_422073_+	hypothetical protein	NA	NA	NA	NA
WP_032461902.1\|422441_422627_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	4.7e-23	85.2
WP_111715292.1\|422697_422952_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	3.8e-39	94.0
WP_111715298.1\|423107_423500_+	helix-turn-helix transcriptional regulator	W6LMS6	Streptococcus_phage	6.8e-11	49.3
WP_008087492.1\|423487_423670_+	hypothetical protein	NA	NA	NA	NA
WP_111715301.1\|423779_424091_+	hypothetical protein	A0A1S5PRW6	Streptococcus_phage	2.3e-22	49.5
WP_111715304.1\|424077_424770_+	AAA family ATPase	J7KC09	Streptococcus_phage	4.6e-127	96.1
WP_111715307.1\|424871_426101_+	DEAD/DEAH box helicase	J7KK96	Streptococcus_phage	5.6e-229	95.1
WP_111715309.1\|426116_426575_+	DUF669 domain-containing protein	A0A1P8VVN0	Streptococcus_phage	2.2e-77	94.1
WP_011527545.1\|426577_427390_+	bifunctional DNA primase/polymerase	J7KH42	Streptococcus_phage	1.9e-153	97.4
WP_011527546.1\|427379_428855_+	DNA primase	A0A1P8VVM0	Streptococcus_phage	2.4e-242	84.2
WP_111715312.1\|429116_429530_+	hypothetical protein	A0A2H4JHE6	uncultured_Caudovirales_phage	1.6e-15	51.1
WP_011527548.1\|429526_429847_+	VRR-NUC domain-containing protein	A0A1P8VVL5	Streptococcus_phage	1.9e-51	95.3
WP_111715315.1\|429830_430187_+	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	8.5e-53	86.4
WP_111715320.1\|430428_430710_+	DUF1599 domain-containing protein	J7KBY0	Streptococcus_phage	1.3e-32	75.0
WP_111717889.1\|430702_430891_+	hypothetical protein	A3F626	Streptococcus_phage	2.6e-13	97.4
WP_111715323.1\|430887_431154_+	hypothetical protein	Q938M2	Temperate_phage	3.1e-44	96.5
WP_111715326.1\|431163_431385_+	hypothetical protein	Q938M1	Temperate_phage	2.7e-25	96.6
WP_012678849.1\|431381_431588_+	hypothetical protein	NA	NA	NA	NA
WP_111715328.1\|431598_431868_+	hypothetical protein	A7J287	Streptococcus_phage	6.2e-32	84.3
WP_111715331.1\|431959_432316_+	DNA cytosine methyltransferase	A0A218MND0	uncultured_virus	1.2e-27	56.9
WP_164714866.1\|432305_432470_+	hypothetical protein	NA	NA	NA	NA
WP_111715333.1\|432482_433037_+	DUF1642 domain-containing protein	Q9MCL5	Streptococcus_virus	9.2e-30	48.2
WP_164714865.1\|433033_433198_+	hypothetical protein	NA	NA	NA	NA
WP_111715336.1\|433670_434096_+	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	4.7e-58	79.6
WP_111715339.1\|435023_435377_+	helix-turn-helix domain-containing protein	A0A1W6JNP4	Staphylococcus_phage	8.5e-21	47.8
WP_111715342.1\|435366_436656_+\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	5.3e-230	93.2
WP_111715345.1\|436667_438170_+\|portal	phage portal protein	C9W9H5	Streptococcus_virus	3.9e-139	53.8
WP_111715348.1\|438150_439722_+\|capsid	minor capsid protein	E8ZDA1	Streptococcus_phage	3.4e-61	36.6
WP_003052398.1\|439723_439930_+	hypothetical protein	A0A141E1X9	Streptococcus_phage	2.1e-08	36.9
WP_111715351.1\|439926_440346_+	HD domain-containing protein	A0A060QNR4	Streptococcus_phage	7.4e-40	62.5
WP_111715354.1\|440399_440669_+	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	1.6e-32	84.1
WP_099982986.1\|440722_441448_-	hypothetical protein	A0A1S5S8M7	Streptococcus_phage	2.3e-52	45.1
WP_162836003.1\|441587_441764_+	hypothetical protein	A0A1X9I5M8	Streptococcus_phage	3.0e-19	79.3
WP_111715357.1\|441886_442159_+	hypothetical protein	NA	NA	NA	NA
WP_111715360.1\|442221_442965_+	phage antirepressor KilAC domain-containing protein	M1PKL6	Streptococcus_phage	6.7e-76	58.1
WP_111715363.1\|443134_443767_+	DUF4355 domain-containing protein	O34060	Streptococcus_phage	7.3e-23	49.2
WP_111715365.1\|443776_444157_+\|head	head decoration protein	NA	NA	NA	NA
WP_111715368.1\|444159_445209_+\|capsid	major capsid protein	O34062	Streptococcus_phage	1.1e-108	58.7
WP_111715371.1\|445220_445490_+	hypothetical protein	NA	NA	NA	NA
WP_111679346.1\|445499_445853_+\|head,tail	phage head-tail connector protein	A0A2H4J002	uncultured_Caudovirales_phage	3.0e-26	52.1
WP_111713363.1\|445849_446158_+	hypothetical protein	NA	NA	NA	NA
WP_111715374.1\|446138_446504_+	HK97 gp10 family phage protein	A0A097BY98	Enterococcus_phage	2.6e-17	47.1
WP_111715377.1\|446500_446890_+\|capsid	phage capsid protein	B5SP36	Lactococcus_phage	4.6e-44	68.2
WP_111715379.1\|446901_447462_+\|tail	phage major tail protein, TP901-1 family	D7RWD5	Brochothrix_phage	1.3e-26	42.7
WP_111715382.1\|447519_447879_+	hypothetical protein	Q77RZ7	Lactococcus_phage	2.5e-20	46.8
WP_111715385.1\|447920_448250_+	hypothetical protein	A0A1B0Y2Q4	Lactobacillus_phage	3.7e-10	38.4
WP_111715388.1\|448265_452285_+	tape measure protein	A0A286QN99	Streptococcus_phage	1.2e-94	49.6
WP_111715390.1\|452314_453094_+\|tail	phage tail family protein	A3F655	Streptococcus_phage	6.4e-69	56.6
WP_111715392.1\|453090_455148_+\|tail	phage tail protein	A3F656	Streptococcus_phage	0.0e+00	88.5
WP_111715395.1\|455144_456458_+	hypothetical protein	A3F657	Streptococcus_phage	1.6e-48	51.6
WP_111715397.1\|456460_457057_+	hypothetical protein	A3F658	Streptococcus_phage	5.2e-55	51.4
WP_111715400.1\|457067_458954_+	gp58-like family protein	A7J2A9	Streptococcus_phage	4.5e-100	69.6
WP_111715403.1\|458967_459138_+	hypothetical protein	NA	NA	NA	NA
WP_111715406.1\|459140_459752_+	DUF1366 domain-containing protein	Q938J7	Temperate_phage	6.7e-74	83.7
WP_002988799.1\|459762_460062_+	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
WP_002988802.1\|460058_460244_+	hypothetical protein	Q938J5	Temperate_phage	9.5e-24	93.4
WP_111715409.1\|460354_461572_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	3.4e-162	59.0
WP_111715411.1\|461726_462251_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	7.5e-98	98.9
WP_111715414.1\|462238_463105_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.7e-126	95.5
WP_111715417.1\|463238_463421_+	Paratox	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_111715420.1\|463530_466623_+	SNF2 helicase associated domain-containing protein	M1H5J5	Paramecium_bursaria_Chlorella_virus	5.0e-40	27.2
463487:463509	attR	NA	NA	NA	NA
WP_111715423.1\|466863_467469_+	hypothetical protein	NA	NA	NA	NA
WP_111715426.1\|467512_468844_+	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_111715428.1\|468890_469373_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_111715431.1\|469484_471092_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_003046783.1\|471164_471647_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_003062080.1\|471857_472781_-	membrane protein insertase YidC	NA	NA	NA	NA
WP_111715433.1\|472863_473142_-	acylphosphatase	NA	NA	NA	NA
WP_111715435.1\|473404_474142_+	RNA methyltransferase	NA	NA	NA	NA
WP_003049766.1\|474180_474681_+	HD domain-containing protein	NA	NA	NA	NA
WP_003059008.1\|474695_475385_+	Bax inhibitor-1/YccA family protein	NA	NA	NA	NA
WP_003049770.1\|475910_476153_+	YneF family protein	NA	NA	NA	NA
WP_111715438.1\|476332_477127_+	glutamate racemase	NA	NA	NA	NA
WP_111715441.1\|477123_478110_+	nucleoside-triphosphate diphosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	8.5e-10	31.6
WP_111715444.1\|478088_478610_+	metallophosphoesterase	NA	NA	NA	NA
WP_003061373.1\|478606_479068_+	CBS domain-containing protein	NA	NA	NA	NA
WP_111715447.1\|479064_479811_+	site-specific tyrosine recombinase XerD	NA	NA	NA	NA
WP_111715450.1\|479810_480518_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	9.1e-06	21.9
WP_111715453.1\|480514_481078_+	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	2.5e-14	33.3
WP_111715455.1\|481190_481913_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_111715458.1\|481909_482161_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.2e-15	53.2
WP_111715460.1\|482352_482898_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA

DBSCAN-SWA_5

504306 : 515731

Streptococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_022554291.1\|504306_505071_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.2e-17	28.3
WP_171841621.1\|505076_505781_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.0e-17	28.4
WP_111715501.1\|505825_506488_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	7.1e-61	57.4
WP_111715504.1\|506574_507210_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.3e-69	66.3
WP_111715507.1\|507225_508098_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.1e-56	42.1
WP_111715509.1\|508094_508895_+	signal peptidase II	NA	NA	NA	NA
WP_003058686.1\|508887_509211_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	7.0e-30	64.2
WP_111715512.1\|509215_510079_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.8e-117	76.7
WP_111715515.1\|510105_510498_+	hypothetical protein	NA	NA	NA	NA
WP_111715517.1\|510544_511174_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_111715519.1\|511290_512382_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	4.1e-130	63.4
WP_111715521.1\|512407_512959_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.0e-49	53.6
WP_111715524.1\|513027_513525_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	6.7e-40	52.3
WP_111715527.1\|513521_513878_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	9.1e-39	62.4
WP_111715530.1\|513928_514351_-	VOC family protein	NA	NA	NA	NA
WP_111715532.1\|514352_514742_-	VOC family protein	NA	NA	NA	NA
WP_111715535.1\|514903_515731_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.2e-127	78.8

DBSCAN-SWA_6

519994 : 626113

103

Staphylococcus_phage(16.13%)

bacteriocin,protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111715146.1\|519994_520939_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	5.1e-20	27.9
WP_111715543.1\|526259_527927_+	hypothetical protein	NA	NA	NA	NA
WP_111715545.1\|528209_528917_+	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_164714863.1\|529184_531182_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	6.0e-87	35.7
WP_111715547.1\|531710_532724_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.9e-98	53.4
WP_003055616.1\|532727_533201_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	F8WQ19	Bacillus_phage	3.7e-11	37.8
WP_111715550.1\|533184_535371_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	9.9e-168	43.1
WP_111715553.1\|535669_537004_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_111715556.1\|537402_537756_+	hypothetical protein	NA	NA	NA	NA
WP_003054401.1\|538120_538357_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_111715558.1\|538349_539048_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_003049859.1\|539044_539287_+	DUF3977 family protein	NA	NA	NA	NA
WP_111715561.1\|539303_539753_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_111715564.1\|539754_540717_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_111715566.1\|540877_542260_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	1.6e-30	35.6
WP_111715568.1\|542290_542845_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003054365.1\|542845_543097_+	hypothetical protein	NA	NA	NA	NA
WP_111715571.1\|543114_543810_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_003059888.1\|543882_544530_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_003054333.1\|544675_545608_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111715574.1\|545672_546398_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	6.2e-18	32.2
WP_111715577.1\|546398_547247_+	metal ABC transporter permease	NA	NA	NA	NA
WP_111715580.1\|547377_548184_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	2.1e-22	37.8
WP_111714653.1\|548523_549783_+\|transposase	transposase	NA	NA	NA	NA
WP_111717893.1\|550001_552410_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.5e-87	51.1
WP_012766635.1\|552478_552832_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_111714653.1\|553122_554382_+\|transposase	transposase	NA	NA	NA	NA
WP_003049875.1\|554674_555100_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_003049876.1\|555205_555895_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_111715582.1\|556171_556567_-	hypothetical protein	NA	NA	NA	NA
WP_003049878.1\|556848_557577_+	UMP kinase	NA	NA	NA	NA
WP_111715585.1\|557606_558164_+	ribosome recycling factor	NA	NA	NA	NA
WP_111715588.1\|558283_559141_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_111715591.1\|559212_559722_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_003060598.1\|559718_559934_+	YozE family protein	NA	NA	NA	NA
WP_111715594.1\|560072_561239_+	LysM peptidoglycan-binding domain-containing protein	A0A2P1N5D1	Gordonia_phage	1.0e-14	39.3
WP_111715596.1\|561300_562254_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	2.3e-20	33.3
WP_111715599.1\|562609_564382_+	oleate hydratase	NA	NA	NA	NA
WP_111715604.1\|564542_565604_+	PhoH family protein	W8D063	Erwinia_phage	2.5e-47	48.6
WP_111715607.1\|565650_566226_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_111715610.1\|566384_566882_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_003054389.1\|566862_567270_+	diacylglycerol kinase	NA	NA	NA	NA
WP_111715613.1\|567390_568287_+	GTPase Era	NA	NA	NA	NA
WP_111715615.1\|568473_568950_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_111715618.1\|570078_570324_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_111715620.1\|570441_571617_+\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	9.4e-32	33.2
WP_164714919.1\|571649_571841_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|573068_573296_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_003060803.1\|573308_573509_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_012766652.1\|573803_573998_+	hypothetical protein	NA	NA	NA	NA
WP_046176962.1\|574047_574329_+	hypothetical protein	NA	NA	NA	NA
WP_003061293.1\|574522_574933_+	hypothetical protein	NA	NA	NA	NA
WP_111717895.1\|575400_575703_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_111715596.1\|575718_576672_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	2.3e-20	33.3
WP_111717897.1\|577066_577864_+	hypothetical protein	NA	NA	NA	NA
WP_111715625.1\|577984_578263_-	StcA family protein	NA	NA	NA	NA
WP_111715628.1\|578300_579902_-	transglutaminase	NA	NA	NA	NA
WP_134771781.1\|579970_580039_-	peptide pheromone SHP2	NA	NA	NA	NA
WP_111715631.1\|580126_580981_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_003049903.1\|580992_581151_+	hypothetical protein	NA	NA	NA	NA
WP_111715633.1\|581162_581990_+	DNA-formamidopyrimidine glycosylase	G3MA33	Bacillus_virus	1.4e-26	32.7
WP_172454452.1\|581968_582580_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_003056868.1\|583032_583734_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-24	34.1
WP_111715635.1\|583723_585361_+	hypothetical protein	NA	NA	NA	NA
WP_111715638.1\|585471_586974_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	3.2e-77	43.5
WP_111715643.1\|587152_588355_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003047126.1\|588351_588498_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_003047129.1\|588543_588780_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_164714862.1\|588876_591207_+	ribonuclease R	Q0GXV6	Lactococcus_phage	4.4e-89	39.6
WP_111715648.1\|591209_591677_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	9.8e-41	56.6
WP_111715650.1\|592275_593202_-	glycosyltransferase family 2 protein	V5USA4	Oenococcus_phage	3.6e-79	47.9
WP_111715653.1\|593338_594523_-	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	9.4e-72	51.0
WP_003049924.1\|594868_595246_-	VOC family protein	NA	NA	NA	NA
WP_111715656.1\|595256_595922_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_111717901.1\|595965_597051_-	aminopeptidase P family protein	NA	NA	NA	NA
WP_003049927.1\|597224_598226_+	catabolite control protein A	NA	NA	NA	NA
WP_111715658.1\|598380_599844_+	alpha-amylase	NA	NA	NA	NA
WP_111715661.1\|599920_600919_+	glycosyltransferase	NA	NA	NA	NA
WP_111715663.1\|600920_602255_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_111715666.1\|602678_604622_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	5.6e-122	39.1
WP_111715669.1\|604807_605800_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	6.7e-15	29.9
WP_111715672.1\|605801_606620_+	ABC-2 family transporter protein	NA	NA	NA	NA
WP_111715675.1\|606621_607407_+	ABC-2 family transporter protein	NA	NA	NA	NA
WP_111715678.1\|607511_608501_-	DhaKLM operon coactivator DhaQ	NA	NA	NA	NA
WP_111715680.1\|608515_609052_-	dihydroxyacetone kinase transcriptional activator DhaS	NA	NA	NA	NA
WP_111715683.1\|609203_610193_+	dihydroxyacetone kinase subunit DhaK	NA	NA	NA	NA
WP_111715685.1\|610203_610779_+	dihydroxyacetone kinase subunit L	NA	NA	NA	NA
WP_003057223.1\|610778_611153_+	PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM	NA	NA	NA	NA
WP_111715688.1\|611170_611881_+	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	6.7e-33	34.1
WP_111715690.1\|612015_612585_+	hypothetical protein	NA	NA	NA	NA
WP_111715693.1\|612553_613669_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_111715696.1\|613658_614903_+	AMP-binding protein	NA	NA	NA	NA
WP_111715699.1\|614997_615993_+	DUF3114 domain-containing protein	NA	NA	NA	NA
WP_111715068.1\|616068_617216_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-49	42.0
WP_111715701.1\|617258_617891_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_111715704.1\|617905_618607_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_111715707.1\|618620_619421_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_003057217.1\|619420_620215_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-36	40.4
WP_003049952.1\|620474_621185_+	response regulator transcription factor	W8CYM9	Bacillus_phage	5.7e-40	39.4
WP_003049953.1\|621177_622530_+	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.1e-35	35.0
WP_003059746.1\|622533_623343_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.1e-36	37.5
WP_111715620.1\|624019_625195_-\|transposase	IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	9.4e-32	33.2
WP_003057240.1\|625420_626113_+	ribonuclease III	A0A167RGU4	Powai_lake_megavirus	2.5e-24	31.6

DBSCAN-SWA_7

1207287 : 1273811

Streptococcus_phage(22.22%)

bacteriocin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111716632.1\|1207287_1208421_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_111716635.1\|1208582_1209959_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_111716637.1\|1210102_1211584_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	7.2e-255	91.5
WP_111716639.1\|1211589_1212999_-	dipeptidase PepV	NA	NA	NA	NA
WP_111716642.1\|1213176_1213779_-	nitroreductase family protein	NA	NA	NA	NA
WP_111716645.1\|1214091_1215831_+	pyruvate oxidase	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	1.4e-36	26.2
WP_111716647.1\|1215884_1217669_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_111717933.1\|1217689_1217947_-	HAD hydrolase family protein	NA	NA	NA	NA
WP_111716649.1\|1218002_1219379_-	NAD-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_164714903.1\|1219455_1220163_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_111716655.1\|1220178_1220745_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_111716657.1\|1220911_1221418_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_111716660.1\|1221514_1222564_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_111716662.1\|1222550_1223345_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_111716664.1\|1223348_1224998_-	sensor histidine kinase	NA	NA	NA	NA
WP_003051128.1\|1225143_1225971_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_003051133.1\|1225967_1226777_-	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_003051135.1\|1226792_1227284_-	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_111716667.1\|1227302_1227728_-	PTS mannose transporter subunit IIA	NA	NA	NA	NA
WP_111716669.1\|1227934_1228954_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_111716672.1\|1229063_1230233_-	DUF2974 domain-containing protein	NA	NA	NA	NA
WP_111716675.1\|1230422_1230719_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_111716678.1\|1230955_1231606_-	HD domain-containing protein	A0A1D6Y7U0	Golden_Marseillevirus	3.9e-11	26.9
WP_111716680.1\|1231618_1232056_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_111716682.1\|1232230_1234063_-	elongation factor 4	A0A2K9L2P9	Tupanvirus	2.2e-19	41.0
WP_111716684.1\|1234132_1234591_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.8e-24	46.3
WP_111716686.1\|1235373_1236036_-	type II-A CRISPR-associated protein Csn2	NA	NA	NA	NA
WP_011106805.1\|1236025_1236367_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_111716689.1\|1237232_1241348_-	type II CRISPR RNA-guided endonuclease Cas9	NA	NA	NA	NA
WP_111716691.1\|1242798_1244271_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.2e-254	91.7
WP_111716693.1\|1244432_1245062_-	TIGR01906 family membrane protein	NA	NA	NA	NA
WP_111716695.1\|1245061_1245826_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_111716697.1\|1245825_1246578_-	acyl-[acyl-carrier-protein] thioesterase	NA	NA	NA	NA
WP_111716700.1\|1246588_1247719_-	oxygen-independent coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_111716702.1\|1247780_1248422_-	hypothetical protein	NA	NA	NA	NA
WP_111716705.1\|1248544_1249900_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_111716708.1\|1249953_1250910_-	YbbR-like domain-containing protein	NA	NA	NA	NA
WP_003056621.1\|1250906_1251758_-	TIGR00159 family protein	NA	NA	NA	NA
WP_164714902.1\|1251861_1253205_+	Mur ligase family protein	NA	NA	NA	NA
WP_111716710.1\|1253204_1253996_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_111716712.1\|1254100_1255090_-	lipoate--protein ligase	NA	NA	NA	NA
WP_111716715.1\|1255173_1256286_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_003051169.1\|1256282_1256597_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_111716717.1\|1256827_1258591_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.8e-34	25.5
WP_111716721.1\|1258917_1260327_-	dihydrolipoamide acetyltransferase	NA	NA	NA	NA
WP_003051182.1\|1260558_1261557_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_037584959.1\|1261615_1262584_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_111716723.1\|1262868_1264776_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.4e-55	31.3
WP_111716724.1\|1264853_1265147_-	hypothetical protein	NA	NA	NA	NA
WP_111716725.1\|1265176_1265962_-	esterase family protein	NA	NA	NA	NA
WP_003056218.1\|1266055_1267717_-	ribonuclease J	NA	NA	NA	NA
WP_111716728.1\|1267929_1268688_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	7.7e-11	27.4
WP_111716730.1\|1268684_1269554_-	ABC transporter permease	NA	NA	NA	NA
WP_111716732.1\|1269571_1270567_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_111714946.1\|1271055_1272189_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_111716737.1\|1272527_1273811_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2028704 : 2106894

Streptococcus_phage(50.0%)

capsid,portal,tail,transposase,protease,terminase,integrase,tRNA

attL 2058778:2058798|attR 2104309:2104329

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111717678.1\|2028704_2031206_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	65.5
WP_111714946.1\|2031376_2032510_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_111717971.1\|2032779_2033685_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002987881.1\|2034334_2034874_-	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_003052994.1\|2035091_2035268_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_003052996.1\|2035280_2035433_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_111717679.1\|2035481_2037830_-	penicillin-binding protein	NA	NA	NA	NA
WP_003054743.1\|2037868_2038249_-	RidA family protein	NA	NA	NA	NA
WP_003053001.1\|2038593_2038785_+	hypothetical protein	NA	NA	NA	NA
WP_111717680.1\|2038768_2039680_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_111717681.1\|2039781_2041422_-	hypothetical protein	NA	NA	NA	NA
WP_111717682.1\|2041703_2043200_+	C69 family dipeptidase	NA	NA	NA	NA
WP_111717683.1\|2043533_2044001_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_012767614.1\|2044218_2045844_-	chaperonin GroEL	A0A219YK78	uncultured_virus	5.1e-153	55.8
WP_111717684.1\|2045879_2046170_-	co-chaperone GroES	NA	NA	NA	NA
WP_111717685.1\|2046347_2048792_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	5.0e-128	39.0
WP_003054759.1\|2048791_2049253_-	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_003053018.1\|2049448_2049652_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.2e-24	81.5
WP_111717686.1\|2050062_2051037_+	amidohydrolase	NA	NA	NA	NA
WP_111717687.1\|2051168_2051624_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_111717688.1\|2051672_2052614_+	2-keto-3-deoxygluconate permease	NA	NA	NA	NA
WP_126442244.1\|2052607_2053009_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_111717690.1\|2053124_2053403_+	N-acetyltransferase	NA	NA	NA	NA
WP_111717691.1\|2053704_2054289_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_111717692.1\|2054276_2054537_+	hypothetical protein	NA	NA	NA	NA
WP_111717693.1\|2054548_2056606_+	sodium:proton antiporter	NA	NA	NA	NA
WP_111717694.1\|2057375_2057984_+	flavin reductase family protein	NA	NA	NA	NA
WP_111717695.1\|2057996_2058617_+	alpha/beta hydrolase	NA	NA	NA	NA
2058778:2058798	attL	NA	NA	NA	NA
WP_111717696.1\|2058847_2059030_-	Paratox	A3F673	Streptococcus_phage	8.5e-17	71.7
WP_111717697.1\|2059199_2059508_+	hypothetical protein	A3F672	Streptococcus_phage	4.0e-43	83.3
WP_111717698.1\|2059539_2060013_+	hypothetical protein	A3F671	Streptococcus_phage	3.0e-82	96.1
WP_111717699.1\|2060014_2060200_+	XRE family transcriptional regulator	B3GW25	Streptococcus_phage	1.8e-14	74.1
WP_011888781.1\|2060297_2060498_-	CsbD family protein	J7KJ36	Streptococcus_phage	5.3e-20	81.8
WP_111714946.1\|2060751_2061885_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_011888780.1\|2062007_2062979_-	Abi family protein	A0A059NT88	Lactococcus_phage	3.3e-75	42.3
WP_111717700.1\|2063284_2064502_-	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	1.7e-164	60.3
WP_011888776.1\|2064615_2064801_-	hypothetical protein	Q938J5	Temperate_phage	1.2e-23	91.8
WP_002988799.1\|2064797_2065097_-	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
WP_111717701.1\|2065107_2065728_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	4.1e-71	83.8
WP_111717702.1\|2065730_2066159_-	DUF1617 family protein	A3F661	Streptococcus_phage	6.0e-69	96.5
WP_111717703.1\|2066170_2068057_-	gp58-like family protein	Q938J9	Temperate_phage	5.9e-177	73.7
WP_111717704.1\|2068067_2068691_-	hypothetical protein	A3F658	Streptococcus_phage	1.9e-55	51.4
WP_111717705.1\|2068693_2070091_-	hypothetical protein	A3F657	Streptococcus_phage	1.2e-70	43.4
WP_111717706.1\|2070087_2072235_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	91.6
WP_111717707.1\|2072231_2072948_-\|tail	phage tail family protein	Q938K2	Temperate_phage	3.4e-133	95.4
WP_111717708.1\|2072944_2076205_-	tape measure protein	Q938K3	Temperate_phage	0.0e+00	95.8
WP_111717709.1\|2076194_2076776_-	hypothetical protein	Q938K4	Temperate_phage	2.6e-99	92.7
WP_111717710.1\|2076779_2077214_-	hypothetical protein	Q938K5	Temperate_phage	2.1e-61	86.1
WP_111717711.1\|2077256_2077745_-\|tail	phage tail protein	Q938K6	Temperate_phage	2.9e-72	88.2
WP_111717712.1\|2077744_2078143_-\|capsid	capsid protein	Q79S87	Temperate_phage	5.5e-69	97.7
WP_111717713.1\|2078139_2078496_-\|capsid	capsid protein	Q79S88	Temperate_phage	7.7e-62	98.3
WP_111717714.1\|2078495_2078828_-\|capsid	minor capsid protein	Q79S86	Temperate_phage	5.3e-57	96.4
WP_164714920.1\|2078817_2079219_-	hypothetical protein	Q938K7	Temperate_phage	5.8e-50	86.5
WP_111717716.1\|2079244_2079514_-	hypothetical protein	K4JTJ0	Streptococcus_phage	1.7e-05	42.4
WP_111717717.1\|2079523_2080360_-\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	6.3e-139	95.2
WP_111717718.1\|2080363_2080978_-	hypothetical protein	Q938K8	Temperate_phage	1.1e-89	94.1
WP_111717719.1\|2081107_2081374_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	3.3e-33	83.0
WP_111715146.1\|2081411_2082356_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	5.1e-20	27.9
WP_111717720.1\|2082511_2082739_-	hypothetical protein	NA	NA	NA	NA
WP_111717721.1\|2082738_2084232_-\|capsid	phage minor capsid protein	Q938L1	Temperate_phage	3.7e-206	77.6
WP_111717722.1\|2084236_2085739_-\|portal	phage portal protein	Q938L2	Temperate_phage	2.4e-274	96.2
WP_164714885.1\|2085752_2087048_-\|terminase	PBSX family phage terminase large subunit	A0A1S5SA45	Streptococcus_phage	2.3e-220	85.0
WP_050318691.1\|2087040_2087736_-\|terminase	terminase	A0A2H4J4R0	uncultured_Caudovirales_phage	4.4e-29	34.5
WP_002988747.1\|2087855_2088272_-	DUF722 domain-containing protein	A7J289	Streptococcus_phage	6.6e-73	100.0
WP_111717723.1\|2088268_2088460_-	hypothetical protein	NA	NA	NA	NA
WP_111717724.1\|2088463_2088730_-	hypothetical protein	A7J287	Streptococcus_phage	9.2e-20	63.5
WP_164714884.1\|2088726_2088894_-	hypothetical protein	A7J285	Streptococcus_phage	4.3e-23	92.7
WP_002983414.1\|2088894_2090217_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	4.6e-253	98.0
WP_111717725.1\|2090213_2090489_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	1.3e-45	97.8
WP_111717726.1\|2090855_2093240_-	DNA primase	A7J282	Streptococcus_phage	2.7e-288	98.4
WP_111717727.1\|2093244_2095167_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	99.1
WP_002983410.1\|2095209_2095773_-	DUF2815 family protein	D2J040	Enterococcus_phage	7.4e-51	57.9
WP_002983409.1\|2095786_2096944_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.7e-219	99.7
WP_043024982.1\|2096943_2097243_-	hypothetical protein	A7J277	Streptococcus_phage	2.0e-39	93.9
WP_002983407.1\|2097330_2097534_-	hypothetical protein	A7J276	Streptococcus_phage	9.4e-33	100.0
WP_111717728.1\|2097679_2098063_-	hypothetical protein	A7J274	Streptococcus_phage	7.2e-58	89.8
WP_050317062.1\|2098059_2098266_-	hypothetical protein	NA	NA	NA	NA
WP_111717729.1\|2098258_2098429_-	hypothetical protein	A7J273	Streptococcus_phage	1.5e-20	92.9
WP_003052448.1\|2098425_2098701_-	hypothetical protein	A7J272	Streptococcus_phage	2.0e-46	96.7
WP_111717730.1\|2098761_2099562_-	phage antirepressor KilAC domain-containing protein	A0A1Q1PVU2	Staphylococcus_phage	1.4e-63	48.7
WP_001283052.1\|2099572_2099764_-	hypothetical protein	A7J270	Streptococcus_phage	7.3e-27	100.0
WP_111717731.1\|2100521_2100869_+	helix-turn-helix transcriptional regulator	A0A1S5SFC6	Streptococcus_phage	1.1e-41	74.6
WP_111705753.1\|2100872_2101259_+	ImmA/IrrE family metallo-endopeptidase	Q7Y4M1	Streptococcus_phage	2.2e-38	58.4
WP_111717732.1\|2101276_2102869_+	SIR2 family protein	A0A1S5SA14	Streptococcus_phage	1.8e-142	70.1
WP_111717733.1\|2103129_2104203_+\|integrase	site-specific integrase	B3GVW7	Streptococcus_phage	4.0e-122	61.9
WP_003058719.1\|2104780_2105341_+	peroxiredoxin	NA	NA	NA	NA
2104309:2104329	attR	NA	NA	NA	NA
WP_111717734.1\|2105361_2106894_+	alkyl hydroperoxide reductase subunit F	V9VEY6	Lactococcus_phage	1.5e-21	29.4

DBSCAN-SWA_9

2152723 : 2164222

Streptococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111717763.1\|2152723_2155279_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	6.6e-38	25.0
WP_111717764.1\|2155265_2155619_-	YlbF family regulator	NA	NA	NA	NA
WP_003055516.1\|2155615_2156053_-	arginine repressor	NA	NA	NA	NA
WP_111717765.1\|2156340_2158032_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	4.9e-74	32.4
WP_111717766.1\|2158101_2159499_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	3.8e-48	28.3
WP_111717767.1\|2159675_2160590_-	YitT family protein	M1Q1P6	Streptococcus_phage	3.0e-54	40.8
WP_111717768.1\|2160619_2161519_-	YitT family protein	M1Q1P6	Streptococcus_phage	7.9e-47	34.9
WP_003055524.1\|2161539_2162481_-	YitT family protein	NA	NA	NA	NA
WP_111717769.1\|2162473_2164222_-\|tRNA	aspartate--tRNA ligase	A0A1V0SJ84	Klosneuvirus	1.0e-13	25.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483361

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection