CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_LS483381	Streptococcus sobrinus strain NCTC10921 chromosome 1	2 crisprs	DEDDh,cas3,csa3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,csm6,DinG	0	5	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_LS483381_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483381_1

448576-448659

Orphan

Consensus_repeat	Method
CCAGGCTGTTTTGACACTTGCTAGGCAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_LS483381_1

>merge|NZ_LS483381|1|448576-448659|CRISPRCasFinder
CCAGGCTGTTTTGACACTTGCTAGGCAAGTTTCATTTCCAACTTTTGACAGTCTCCCAGACTGTTTTGACACTTGCTAGGCAAG

>NZ_LS483381|1|1|448576-448659|CRISPRCasFinder
CCAGGCTGTTTTGACACTTGCTAGGCAAG	TTTCATTTCCAACTTTTGACAGTCTC
CCAGACTGTTTTGACACTTGCTAGGCAAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483381.1\|WP_019795285.1\|454745_455864_+\|ribosome-biogenesis-GTPase-YqeH	unknown	unknown	gnl\|CDD\|237511
NZ_LS483381.1\|WP_002960026.1\|442716_443019_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810
NZ_LS483381.1\|WP_111687993.1\|440537_441557_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_LS483381.1\|WP_019772629.1\|443018_444485_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl\|CDD\|234572
NZ_LS483381.1\|WP_002960819.1\|456297_456609_+\|ribosome-assembly-RNA-binding-protein-YhbY	unknown	unknown	gnl\|CDD\|224451
NZ_LS483381.1\|WP_109982439.1\|435280_435832_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NZ_LS483381.1\|WP_019771855.1\|441774_442551_-\|conjugal-transfer-protein-TraX	unknown	unknown	gnl\|CDD\|368639
NZ_LS483381.1\|WP_019770651.1\|453198_453513_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NZ_LS483381.1\|WP_019769124.1\|454218_454746_+\|YqeG-family-HAD-IIIA-type-phosphatase	unknown	unknown	gnl\|CDD\|225090
NZ_LS483381.1\|WP_019769840.1\|446851_447967_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|180482
NZ_LS483381.1\|WP_019769841.1\|445927_446128_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483381.1\|WP_002960840.1\|449399_450275_+\|DUF3114-domain-containing-protein	unknown	unknown	gnl\|CDD\|337977
NZ_LS483381.1\|WP_019770647.1\|455879_456251_+\|MGMT-family-protein	unknown	unknown	gnl\|CDD\|376440
NZ_LS483381.1\|WP_019769115.1\|450343_451099_-\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|183775
NZ_LS483381.1\|WP_019790496.1\|453505_453766_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NZ_LS483381.1\|WP_019772630.1\|444484_445927_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NZ_LS483381.1\|WP_019769123.1\|453903_454002_+\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NZ_LS483381.1\|WP_109982441.1\|451638_452364_+\|DUF4352-domain-containing-protein	unknown	unknown	gnl\|CDD\|367814
NZ_LS483381.1\|WP_002962942.1\|436672_437374_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NZ_LS483381.1\|WP_019768899.1\|435994_436552_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NZ_LS483381.1\|WP_019795285.1\|454745_455864_+\|ribosome-biogenesis-GTPase-YqeH	gnl\|CDD\|237511	PRK13796, PRK13796, GTPase YqeH; Provisional.	0
NZ_LS483381.1\|WP_109982441.1\|451638_452364_+\|DUF4352-domain-containing-protein	gnl\|CDD\|367814	pfam04103, CD20, CD20-like family. This family includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc. The high affinity receptor for IgE is a tetrameric structure consisting of a single IgE-binding alpha subunit, a single beta subunit, and two disulfide-linked gamma subunits. The alpha subunit of Fc epsilon RI and most Fc receptors are homologous members of the Ig superfamily. By contrast, the beta and gamma subunits from Fc epsilon RI are not homologous to the Ig superfamily. Both molecules have four putative transmembrane segments and a probably topology where both amino- and carboxy termini protrude into the cytoplasm. This family also includes LR8 like proteins from humans, mice and rats. The function of the human LR8 protein is unknown although it is known to be strongly expressed in the lung fibroblasts. This family also includes sarcospan is a transmembrane component of dystrophin-associated glycoprotein. Loss of the sarcoglycan complex and sarcospan alone is sufficient to cause muscular dystrophy. The role of the sarcoglycan complex and sarcospan is thought to be to strengthen the dystrophin axis connecting the basement membrane with the cytoskeleton.	3.19552e-05
NZ_LS483381.1\|WP_111687993.1\|440537_441557_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	5.62021e-82
NZ_LS483381.1\|WP_019772629.1\|443018_444485_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NZ_LS483381.1\|WP_002960819.1\|456297_456609_+\|ribosome-assembly-RNA-binding-protein-YhbY	gnl\|CDD\|224451	COG1534, COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis].	9.43411e-32
NZ_LS483381.1\|WP_109982439.1\|435280_435832_+\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	4.30106e-45
NZ_LS483381.1\|WP_019771855.1\|441774_442551_-\|conjugal-transfer-protein-TraX	gnl\|CDD\|368639	pfam05857, TraX, TraX protein. This family consists of several bacterial TraX proteins. TraX is responsible for the amino-terminal acetylation of F-pilin subunits.	1.18952e-21
NZ_LS483381.1\|WP_019770651.1\|453198_453513_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	1.2862e-06
NZ_LS483381.1\|WP_019769124.1\|454218_454746_+\|YqeG-family-HAD-IIIA-type-phosphatase	gnl\|CDD\|225090	COG2179, COG2179, Predicted hydrolase of the HAD superfamily [General function prediction only].	5.37287e-85
NZ_LS483381.1\|WP_019769840.1\|446851_447967_+\|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase	gnl\|CDD\|180482	PRK06233, PRK06233, vitamin B12 independent methionine synthase.	2.22157e-136
NZ_LS483381.1\|WP_002960026.1\|442716_443019_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	8.74272e-34
NZ_LS483381.1\|WP_002960840.1\|449399_450275_+\|DUF3114-domain-containing-protein	gnl\|CDD\|337977	pfam11311, DUF3114, Protein of unknown function (DUF3114). Some members in this family of proteins with unknown function are annotated as cytosolic proteins. This cannot be confirmed.	1.2103e-97
NZ_LS483381.1\|WP_019770647.1\|455879_456251_+\|MGMT-family-protein	gnl\|CDD\|376440	pfam01035, DNA_binding_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain. This domain is a 3 helical bundle.	4.8187e-12
NZ_LS483381.1\|WP_019769115.1\|450343_451099_-\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|183775	PRK12826, PRK12826, SDR family oxidoreductase.	1.15966e-94
NZ_LS483381.1\|WP_019790496.1\|453505_453766_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	7.40079e-07
NZ_LS483381.1\|WP_019772630.1\|444484_445927_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NZ_LS483381.1\|WP_002962942.1\|436672_437374_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.65538e-105
NZ_LS483381.1\|WP_019768899.1\|435994_436552_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	7.91982e-09

>NZ_LS483381.1|WP_019769840.1|446851_447967_+|5-methyltetrahydropteroyltriglutamate---homocysteine-S-methyltransferase
MTKKYFEHVGSFLRPVELKEAREAFEAGKLSQEELTAVENRLITDLVDKQVAIGLEKITDGEFRRAYWHLDNFWGFDGVEHEHFGQGYLFHGEETGDDTAVLRGKLGFTKENHPFIAHYDFYKKLADERGVEAKITIPAPAQFLAELNRGKNAATVAEFYPSRQDFLRAIAEVYREEILALYETGARTVQLDDCTWGMLIDEDFWHTMAGAGFKKEDVIEEYLYVNNNAIKDLPSDLTINTHVCRGNFHSTYAAKGAYDDVAEAFFGRENARAYFLEYDNERSGGFEPLAAFKGLDKVAVLGLITTKDGQLEDKETIIQRIHEAAEILPLDQLWLATQCGFASTQEGNILTEEDQWKKLTLVKEIIDEVWG
>NZ_LS483381.1|WP_019769841.1|445927_446128_+|hypothetical-protein
MGALLVYLIFFLPMLMISYCFSIFQHFRVKAIAKRGQELRLWARSLGIEENRGSRGVILYTHYINF
>NZ_LS483381.1|WP_019772630.1|444484_445927_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MNFETIIGLEVHVELNTNSKIFSPSSAHFGENPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHQTMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWLEAQLDDGSIKKIRIERAHLEEDAGKNTHADDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTTLKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEEFGTKTELKNLNSFSNVRKGLEYEVERQAKILRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPIFEISDDWIEEMRDSLPEFAKDRRARYVSQYGLSDYDANQLTASKATSDFFEAAVGLGGDAKQVSNWLQGEVAQFLNSENKNLEDIQLTPDNLVEMLGLIEDSTISSKIAKKVFVHLAKNGDGARDYVEKAGLVQISDPEILIPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVALKLLAQELAKLKEE
>NZ_LS483381.1|WP_019772629.1|443018_444485_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MSFNDKTIEELHDLLVKKEISATELTQATLEDINAREETIGSFITVAQEEALAQAKSLDEQGIDADNVLSGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATAVANAKQKGMIVVGKTNMDEFAMGGSTETSYFKKTKNAWDQSKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRFGLIAFGSSLDQIGPFAQTVKENAQVLNAIASEDKKDSTSAPVRISDYTSKIGQDIKGMRIALPKEYLGKGIDPQIKDNVLAAAKQFEKLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGVRYGFRADDANSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFADYDLILGPTSPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISLPSGFVDGLPVGLQLIGPKYGEETIYQAAAAFEAVTDYHKQRPKIFGGDH
>NZ_LS483381.1|WP_002960026.1|442716_443019_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MKISEEEVRHVATLSKLAFSDEETTEFATTLTKIVDMVELLNEVDTTGVAITTTMADRRTVLRPDVAEEGTDRDQLFKNVPEAKDYYIKVPAILDDGGDA
>NZ_LS483381.1|WP_019771855.1|441774_442551_-|conjugal-transfer-protein-TraX
MKKSIGLNTNQLKYIALSFMVLDSAFFAFPGLPAWLHLITRFVAPLFAYLTLEGFFHTRNRKRHLLRLWSVAILMQIGDFLSQLLLGKEHLINDNIFLTLALGYSFLYFWQKARDHDRPILNSVLGSLIFLAGLFLSLIGLPFGAMVITLEGGIPILTLMLIFWAFYGHRRKQLIVFGIWSVISFLILGPDMNVSAAPSFSVWFEMFCYNSDCMSFLFLPFLFLYNGQKGSSKPIHKWFFYIFYPLHLWILHLLAFFL
>NZ_LS483381.1|WP_111687993.1|440537_441557_-|IS30-family-transposase
MSTTNCTTKQPYCHLSEVERGKIEAFLSEGVKPAEIARRLGRSRSTISREIKRGTTKQVKQVNGKKIYFDYYFADLAQRRYVEGRQGIDYLKLEKVSEHFLKAFEEAMKASPRVHSVESFVYAYKEEHPSETVPSTKTLYNYSHQGLLAIKAIDLPKAVRLRKKTKKRSSTQKHLGVSIEERPETINDRSVFGHWEIDSVLGTQKAGEPSILTLVERKTRYAITAYLTGKTAATANEAVKELMGLYPIKSITADNGSEFAALNELEGVQIYYAHAYSSYERGTNENFNGLLREFVPKGKSLKTLTAEDLAKATLAINQRPRRLLNYQTAKTLFGLAQTA
>NZ_LS483381.1|WP_002962942.1|436672_437374_+|ABC-transporter-ATP-binding-protein
MAYIEMKHSYKRYQMGETEIIANNDISFEINKGELVIILGASGAGKSTVLNILGGMDSNDEGQVLIDGNNIAAFNQKQLTAYRRSDVGFVFQFYNLVPNLTAKENVELASEIVDDAKDAALTLHEVGLGSRLNNFPAQLSGGEQQRVAIARALAKNPKLLLCDEPTGALDYQTGKQILKLLQNMSHQKGTTVIIVTHNASLAPIADRVIYLHDAKVNAINTNDWPQDIDTLEY
>NZ_LS483381.1|WP_019768899.1|435994_436552_-|TetR/AcrR-family-transcriptional-regulator
MTQKRHTQSKAKIKAAITELLLENNDFSSITIRQITEKANINRSTFYLHYQDKYDLIDKLMHEITDNLRKELNTNSATVKEGLIHSLTYLQSQQEFIKLIIGIAPVNFSQKTRHFISKLIETTPALFYDILNPDLPLPKDYMLTTYAASIESIYTHWVSTDNQASPEEVANMILTVRRFYQKNDD
>NZ_LS483381.1|WP_109982439.1|435280_435832_+|cysteine-hydrolase
MPKALISIDYTYDFVADDGKLTAGQPAQMIEAAIAAKTKAAYEAGDYIIFAVDSHDERDYFHPETRLFPPHNIKGTKGRELYGQLANVYETIKSDDRVFWMDKRHYSAFAGTDLDIRLRERRVTSLVLTGVLTDICVLHTAVDAYNLGYDMEIPASCVASLTQENHDWALYHFKNVLGAEIVD
>NZ_LS483381.1|WP_002960840.1|449399_450275_+|DUF3114-domain-containing-protein
MPKIGSAAFWSGWKEVKNDKDPCRALRFVLDQLDLPQDLSGDLTENQALVAKFSPDLAPHDRFWSDLARQVRLVMKGKDFQEKTEFNRQLHQLRYVISSQQAQYVRQHYRKSGRTDQEALFAYLRANHLRPSLWDNARLHNKRQIKDGTFCFPDEQESYNIKVLLQFRTEFIIDGQGNFLNEVDAEKVTANGIINGASFNYGNTTKSHFRLDVCPVGPHDPAFRNQATKGYRSPNRTGRVRLARFWQERRTADFDRSLYNKNGGYAKDGQALISLIKQEKKAFKKALRARK
>NZ_LS483381.1|WP_019769115.1|450343_451099_-|3-oxoacyl-ACP-reductase-FabG
MFQLTNQIAVVTGGAKGIGRGIASVLHQQGAKVIILDKDQAAGQATAKNLGADFYSFNVTDSQGIAQTFQMIAEKYGRLDILCSNIGIYPQAKIADMSEAEWDLIQTVNLKGTFLVVKAAAKIMRHQGYGRIVLTSSITGPITGYPGWAHYGSTKAGQLGFMRSAALEYAKAGITINAVQPGNVLTEGLKTQGESYLNEMKKTVPTHTLGAPEDIGTAVAFLASKEAHYITGQTIVVDGGQILPESFDAIL
>NZ_LS483381.1|WP_109982441.1|451638_452364_+|DUF4352-domain-containing-protein
MEPLKEDEKKVLAIIALVFGGIALVTSWMPFINNASAVLAIIAFILGVIAFFINLKKKKVLSLLSIMIAVISFIIVLMTQASYVSTIDKALGSNDKPTSEKQEKKESSSISDSDDDKETYKVGEKITFKGKVEYTITSVEWTDERNEFEDKQPKKVLKVTYNVKNLSDDDYVIGSDFELYANGSKMESYPNENTFETISAGRSYQGATEHFAVNDDKKLELEIKPYLSFRGTPAIIPLESE
>NZ_LS483381.1|WP_019770651.1|453198_453513_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MTKENYQLRFLPLFEKDLNAIVDYISQSLQNPRAAHRLLSAVEGAINDRLARPLAFPAYPSIHKRRHPYYYIRVKNLIIFYVVIGNTMEVRKILYSKRNFDDFL
>NZ_LS483381.1|WP_019790496.1|453505_453766_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MINIRPVSDLRNKFPEIEETVIKSNDPVFLTKNGYGTMVLMSLEQYDDLTSNLEKKLDEADLVAEESSVRYNKDGLFKRVRSRIDD
>NZ_LS483381.1|WP_019769123.1|453903_454002_+|type-I-toxin-antitoxin-system-Fst-family-toxin
MWKDLFLSIVAPTFVGIVLGLFSKWLNGKDDD
>NZ_LS483381.1|WP_019769124.1|454218_454746_+|YqeG-family-HAD-IIIA-type-phosphatase
MSIEDYLPTFAVEAVYDLKPESLRKHGISAVLVDLDNTLIAWDNPDGTPELREWLDDMTEADIPVVVVSNNKHERVKRAVDPFHVDFISRAMKPFTRGINKAIERYNFNRDEVVLVGDQLMTDIRACHRAGIRSILVKPLVTSDAWNTKFNRARERRVLKKMTQKYGPIEYQKEI
>NZ_LS483381.1|WP_019795285.1|454745_455864_+|ribosome-biogenesis-GTPase-YqeH
MEELYCIGCGAKIQSRDKEAPGYTPQSSIEKSQETGELYCQRCFRLRHYNEIVDVAISDDDFLKLLHEVGDSQALVVNVVDIFDFNGSVIPGLSRFVAGNDVLLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPVDVLLTSAQNGQAIKELIARIEELRAGRDVYVVGVTNVGKSTLINAIIKEITGNQEIITTSRFPGTTLDKIEIPLDDGSYIFDTPGIIHRHQMAHYLSAKDLKYVSPKKEIKPKTYQLNPSQTLFLGGLGRFDFLQGDKQGFTAYFDNNLKLHRTKLQGADDFYDRHAGGLLTPPSAKELANFPKLVRHEFTITSKTDLVFSGLGWVRILAKPDSPVVVVGWAPEGVGVMVRKALI
>NZ_LS483381.1|WP_019770647.1|455879_456251_+|MGMT-family-protein
MTQSSFIAPEKYAEAIRQIPYGKVVTLADLRAYLGQDDSAPFFSGVATLIVAWSEGDDPMPYWRVLKSGGEVNAKYPGGLEAQRELLEAEGHRIIQKGKTKLRYYVKDYQEKSYLFDVKKNLM
>NZ_LS483381.1|WP_002960819.1|456297_456609_+|ribosome-assembly-RNA-binding-protein-YhbY
MTLTSKQRAFLNSQAHAMKPIVQVGKNGLNDQIKTSVRNALDARELIKIKLLQNTDENIHEVAEILEEEIGAQSVAKTGRVLTLYKQSAKKENRKLSQKVKEI

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Crispr_ID: NZ_LS483381_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_LS483381_2

852554-853315

TypeI-E

I-C,I-E,II-B

Consensus_repeat	Method
GTTTTACCCGCACACGCGGGGGTGATCCT	PILER-CR
GTTTTACCCGCACACGCGGGGGTGATCCT	CRISPRCasFinder
GTTTTACCCGCACACGCGGGGGTGATCCT	CRT

12 spacers

DEDDh,cas1,cas6e,cas5,cas7,cse2gr11,cas8e

The CRISPR arrays of NZ_LS483381_2

>merge|NZ_LS483381|2|852554-853315|PILER-CR,CRISPRCasFinder,CRT
GTTTTACCCGCACACGCGGGGGTGATCCTAAAGTTCCTGTACAATTTCTGTACGTGTTTTCGTTTTACCCGCACACGCGGGGGTGATCCTGCAGGGGAGATGAGGCGTGTTAAATGCGAGGTGTTTTACCCGCACACGCGGGGGTGATCCTAGAATACCATCCACCTGAGTAGTAGCGAGAGGGTTTTACCCGCACACGCGGGGGTGATCCTGCTTTATCAAATGCTGCTGAGCAGTCTAGGCAGTTTTACCCGCACACGCGGGGGTGATCCTCAAAGGCCTTGTCAGGTAGGTATTTATCGGTGAGTTTTACCCGCACACGCGGGGGTGATCCTGGTCTATCTGGTCAAGGTTCTTGACAGAAGTAGTTTTACCCGCACACGCGGGGGTGATCCCGCCGGCAAAAGCTATTCATTCCTTTTAAATTTGTTTTACCCGCACACGCGGGGGTGATCCTGAGTTTACTTATCTCTGGTTGGTTAACAAGTAGTTTTACCCGCACACGCGGGGGTGATCCTTCCAAGCGTTCTTGGATTTCCTGCTGATTAAAGTTTTACCCGCACACGCGGGGGTGATCCTGGTATTTTGACTGCTAGGTTTCATGGCTCGTCGTTTTACCCGCACACGCGAGGGTGATCCTATTTCCTCTCGGCCAAAGCAGTGAAACGGTTAGTTTTACCCGCACATGCGGGGGTGATCCTGGTTTTGGGGATGCTAACTGGTACGAATACTAGTTTTACCCGCACAGGCGGGTGTGGCATA

>NZ_LS483381|2|1|852554-853254|PILER-CR
GTTTTACCCGCACACGCGGGGGTGATCCT	AAAGTTCCTGTACAATTTCTGTACGTGTTTTC
GTTTTACCCGCACACGCGGGGGTGATCCT	GCAGGGGAGATGAGGCGTGTTAAATGCGAGGT
GTTTTACCCGCACACGCGGGGGTGATCCT	AGAATACCATCCACCTGAGTAGTAGCGAGAGG
GTTTTACCCGCACACGCGGGGGTGATCCT	GCTTTATCAAATGCTGCTGAGCAGTCTAGGCA
GTTTTACCCGCACACGCGGGGGTGATCCT	CAAAGGCCTTGTCAGGTAGGTATTTATCGGTGA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTCTATCTGGTCAAGGTTCTTGACAGAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCC	GCCGGCAAAAGCTATTCATTCCTTTTAAATTT
GTTTTACCCGCACACGCGGGGGTGATCCT	GAGTTTACTTATCTCTGGTTGGTTAACAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCT	TCCAAGCGTTCTTGGATTTCCTGCTGATTAAA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTATTTTGACTGCTAGGTTTCATGGCTCGTC
GTTTTACCCGCACACGCGAGGGTGATCCT	ATTTCCTCTCGGCCAAAGCAGTGAAACGGTTA
GTTTTACCCGCACATGCGGGGGTGATCCT

>NZ_LS483381|2|2|852554-853315|CRISPRCasFinder
GTTTTACCCGCACACGCGGGGGTGATCCT	AAAGTTCCTGTACAATTTCTGTACGTGTTTTC
GTTTTACCCGCACACGCGGGGGTGATCCT	GCAGGGGAGATGAGGCGTGTTAAATGCGAGGT
GTTTTACCCGCACACGCGGGGGTGATCCT	AGAATACCATCCACCTGAGTAGTAGCGAGAGG
GTTTTACCCGCACACGCGGGGGTGATCCT	GCTTTATCAAATGCTGCTGAGCAGTCTAGGCA
GTTTTACCCGCACACGCGGGGGTGATCCT	CAAAGGCCTTGTCAGGTAGGTATTTATCGGTGA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTCTATCTGGTCAAGGTTCTTGACAGAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCC	GCCGGCAAAAGCTATTCATTCCTTTTAAATTT
GTTTTACCCGCACACGCGGGGGTGATCCT	GAGTTTACTTATCTCTGGTTGGTTAACAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCT	TCCAAGCGTTCTTGGATTTCCTGCTGATTAAA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTATTTTGACTGCTAGGTTTCATGGCTCGTC
GTTTTACCCGCACACGCGAGGGTGATCCT	ATTTCCTCTCGGCCAAAGCAGTGAAACGGTTA
GTTTTACCCGCACATGCGGGGGTGATCCT	GGTTTTGGGGATGCTAACTGGTACGAATACTA
GTTTTACCCGCACAGGCGGGTGTGGCATA

>NZ_LS483381|2|1|852554-853315|CRT
GTTTTACCCGCACACGCGGGGGTGATCCT	AAAGTTCCTGTACAATTTCTGTACGTGTTTTC
GTTTTACCCGCACACGCGGGGGTGATCCT	GCAGGGGAGATGAGGCGTGTTAAATGCGAGGT
GTTTTACCCGCACACGCGGGGGTGATCCT	AGAATACCATCCACCTGAGTAGTAGCGAGAGG
GTTTTACCCGCACACGCGGGGGTGATCCT	GCTTTATCAAATGCTGCTGAGCAGTCTAGGCA
GTTTTACCCGCACACGCGGGGGTGATCCT	CAAAGGCCTTGTCAGGTAGGTATTTATCGGTGA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTCTATCTGGTCAAGGTTCTTGACAGAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCC	GCCGGCAAAAGCTATTCATTCCTTTTAAATTT
GTTTTACCCGCACACGCGGGGGTGATCCT	GAGTTTACTTATCTCTGGTTGGTTAACAAGTA
GTTTTACCCGCACACGCGGGGGTGATCCT	TCCAAGCGTTCTTGGATTTCCTGCTGATTAAA
GTTTTACCCGCACACGCGGGGGTGATCCT	GGTATTTTGACTGCTAGGTTTCATGGCTCGTC
GTTTTACCCGCACACGCGAGGGTGATCCT	ATTTCCTCTCGGCCAAAGCAGTGAAACGGTTA
GTTTTACCCGCACATGCGGGGGTGATCCT	GGTTTTGGGGATGCTAACTGGTACGAATACTA
GTTTTACCCGCACAGGCGGGTGTGGCATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_LS483381.1\|WP_002959652.1\|864173_864494_+\|hypothetical-protein	unknown	unknown	unknown
NZ_LS483381.1\|WP_109982550.1\|854983_859093_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|334895
NZ_LS483381.1\|WP_021673647.1\|848217_849297_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_LS483381.1\|WP_002962195.1\|837186_837780_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341201
NZ_LS483381.1\|WP_021673823.1\|864887_866297_+\|DUF438-domain-containing-protein	unknown	unknown	gnl\|CDD\|225301
NZ_LS483381.1\|WP_032672906.1\|849306_850032_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|187886
NZ_LS483381.1\|WP_021673649.1\|845945_847619_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NZ_LS483381.1\|WP_109982548.1\|850684_851626_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_LS483381.1\|WP_002962196.1\|836397_836901_+\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NZ_LS483381.1\|WP_002959642.1\|868825_869104_+\|UPF0223-family-protein	unknown	unknown	gnl\|CDD\|179841
NZ_LS483381.1\|WP_002959644.1\|868419_868833_+\|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	unknown	unknown	gnl\|CDD\|179316
NZ_LS483381.1\|WP_002959651.1\|864655_864886_+\|DUF1858-domain-containing-protein	unknown	unknown	gnl\|CDD\|378108
NZ_LS483381.1\|WP_109982549.1\|853449_854805_+\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NZ_LS483381.1\|WP_021673643.1\|851627_852530_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NZ_LS483381.1\|WP_109982551.1\|859398_863925_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|334895
NZ_LS483381.1\|WP_019775920.1\|866372_867257_+\|tRNA-pseudouridine(55)-synthase-TruB	unknown	unknown	gnl\|CDD\|235042
NZ_LS483381.1\|WP_019773967.1\|867262_868180_+\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NZ_LS483381.1\|WP_109982547.1\|838218_842883_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	unknown	unknown	gnl\|CDD\|334895
NZ_LS483381.1\|WP_021673645.1\|850037_850688_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NZ_LS483381.1\|WP_021673648.1\|847631_848228_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0194_cse2gr11_CAS-I-E	gnl\|CDD\|378191

Protein	Function_ID	Function_description	E-value
NZ_LS483381.1\|WP_109982550.1\|854983_859093_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0
NZ_LS483381.1\|WP_021673647.1\|848217_849297_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	5.49918e-156
NZ_LS483381.1\|WP_002962195.1\|837186_837780_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341201	cd17520, RMtype1_S_HmoORF3075P-TRD1-CR1_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Heliobacterium modesticaldum Ice1 S subunit (S1.HmoORF3075P) TRD1-CR1. The recognition sequence of Heliobacterium modesticaldum Ice1 S subunit (S1.HmoORF3075P) is undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This subfamily also includes the TRD-CR-like sequence-recognition domain of type I N6-adenine DNA methyltransferase (M) subunit of Clostridium intestinale URNW (M2.CinURNWORF2828P). The recognition sequence of M2.CinURNWORF2828P is undetermined. Type I methyltransferases included in this group include two domains: one for methylation, and another (TRD-CR-like) for sequence-recognition.	6.12071e-45
NZ_LS483381.1\|WP_021673823.1\|864887_866297_+\|DUF438-domain-containing-protein	gnl\|CDD\|225301	COG2461, COG2461, Uncharacterized conserved protein [Function unknown].	6.76096e-134
NZ_LS483381.1\|WP_032672906.1\|849306_850032_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	3.76664e-45
NZ_LS483381.1\|WP_021673649.1\|845945_847619_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	1.7905e-83
NZ_LS483381.1\|WP_109982548.1\|850684_851626_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	6.91835e-132
NZ_LS483381.1\|WP_002962196.1\|836397_836901_+\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	2.48174e-94
NZ_LS483381.1\|WP_002959642.1\|868825_869104_+\|UPF0223-family-protein	gnl\|CDD\|179841	PRK04387, PRK04387, hypothetical protein; Provisional.	8.78149e-42
NZ_LS483381.1\|WP_002959644.1\|868419_868833_+\|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein	gnl\|CDD\|179316	PRK01655, spxA, transcriptional regulator Spx; Reviewed.	6.24525e-83
NZ_LS483381.1\|WP_002959651.1\|864655_864886_+\|DUF1858-domain-containing-protein	gnl\|CDD\|378108	pfam08984, DUF1858, Domain of unknown function (DUF1858). This domain has no known function. It is found in various hypothetical bacterial proteins.	1.44722e-15
NZ_LS483381.1\|WP_109982549.1\|853449_854805_+\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	2.71313e-176
NZ_LS483381.1\|WP_021673643.1\|851627_852530_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	9.47468e-40
NZ_LS483381.1\|WP_109982551.1\|859398_863925_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0
NZ_LS483381.1\|WP_019775920.1\|866372_867257_+\|tRNA-pseudouridine(55)-synthase-TruB	gnl\|CDD\|235042	PRK02484, truB, tRNA pseudouridine synthase B; Provisional.	0
NZ_LS483381.1\|WP_019773967.1\|867262_868180_+\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.10517e-134
NZ_LS483381.1\|WP_109982547.1\|838218_842883_+\|KxYKxGKxW-signal-peptide-domain-containing-protein	gnl\|CDD\|334895	pfam02324, Glyco_hydro_70, Glycosyl hydrolase family 70. Members of this family belong to glycosyl hydrolase family 70 Glucosyltransferases or sucrose 6-glycosyl transferases (GTF-S) catalyze the transfer of D-glucopyramnosyl units from sucrose onto acceptor molecules, EC:2.4.1.5. This family roughly corresponds to the N-terminal catalytic domain of the enzyme. Members of this family also contain the Putative cell wall binding domain pfam01473, which corresponds with the C-terminal glucan-binding domain.	0
NZ_LS483381.1\|WP_021673645.1\|850037_850688_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	5.81157e-69
NZ_LS483381.1\|WP_021673648.1\|847631_848228_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	9.95823e-39

>NZ_LS483381.1|WP_021673643.1|851627_852530_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MPFTVITVKNAPPSLRGDLTKWMQEIATGVYVGNFNTKVREQLWNRVENSVGHGEATISYSFRNEIGYQFATINAQREVVDYDGIPLVLLPSQAKDVGKNVALGFSNAAKFRKIKRYTSSSQSHVQSTVPYAVIDIETDGLDENEHTIIEIAAVKVSGLQIEDFDYLIKYDKVLPKNIVSLTGISQELLNQNGKDIQVVLQEFLNFIGDFDLVGYGVGFDIKFINNELRKLGYPLLENKVHDLMKYVKNEKLFLDNYKLQTALKVYGIEGEVPHRALPDSRLIYQLSTKVNKFLKRINQK
>NZ_LS483381.1|WP_109982548.1|850684_851626_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MKEKFGAKKTSLKELPKISDRVSFIYVEHAKINRVDSAITVADSKGIVRIPAAMLGVLLLGPGTDISHRAVELIGDTGTSMIWVGEHGVRQYAHGRSLAHSTRFLEKQAKLVSNSRSRLRVARKMYQMRFPNEDVSGLTMQQLRGREGARIRKVYSLQAKKYNIPWTKRDYNPENFEDGTPVNQALSAANVALYGLVHSIIVALGASPGLGFVHTGHDLSFVYDVADLYKAETTIPIAFEIAANCQPGDDIGKITRLKVRDSFVDGKLMIQIVKDLQNLLDIEESEELVVDILALWDDKERLVKHGVSYREDS
>NZ_LS483381.1|WP_021673645.1|850037_850688_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYISRVEIDKNNRRKIKDLKNIESYHGWVEQSFPKEIEQNIRTRKLWRVDQLQGHYYLIIISLEKPDLKLLEKYGVRNSAQTKSYDTFLNSLKEGEVMRFRVVLNPVISLPSRDGNHKRGVVKPHTTIKHQMNYLLNRSEKNGFLLEKDDFSIVERGYEVFNKGNSKPIRLIKAIYEGILTIDDADLFRKTLTEGIGKKKAYGFGMMTAIPLGDEK
>NZ_LS483381.1|WP_032672906.1|849306_850032_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MKTILLKLAGPLQSWGTSSHFETRHTDFYPSKSAIIGLIAASLGYRRDEEQRLQRLNELDFAVRIDQQGNILRDYHIAQKYKSKGEFERTYVTNRYYLEDAIFIVAISHEDDELMSAIEKGLKNPYFQTFMGRRSLPLNADFIVETTSDSALESLKRLKWQAAEWFMSKHSHETSITLEIYADSFLSDKESNRLRQDRVISFSQKARKFGFRYEVRDLVDVSNPMAKKGETQHDIFSSIGD
>NZ_LS483381.1|WP_021673647.1|848217_849297_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTNNQHLFLDIHAIQTLPPSNINRDDTGSPKTAQYGGVRRARVSSQSWKRAIREYFSDNGQQSNVGVRTKDIVRYVADKIIGLDQSISLEDALQKADKVLNGAGVKTKDFKAKALFFLSDVQAKKLAQAAINDVSDKKELHEVLTSSPAIDIALFGRMVADDPSLNEDASSQVAHAISTHAVQTEFDFYTAVDDLAPEDNAGAGMLGTIEFNSSTLYRYANVAVHELLKQLGDKESLVNSLSLFIEAFAKSLPTGKATSFANQTLPQALVVTLRNDRPISLVSAFEKPVKSSEGYVTKSIEKLSDEFVKVEKFVNKPVLTFYVSLEDVEKLKNVGGIEKNSLSELLSDFSEELSNFIQE
>NZ_LS483381.1|WP_021673648.1|847631_848228_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MSEQRKARVAEVTRKILIKLSKQKDTSSGKALLARLRQSIGKPVSETVAVWPILFEDLPEEFLGHDGYTSAEEQAILTTLQLYALHQQSLSHSVFIGEENKYQNIGNSFRQLRQGEDTTAIDRRFNVMITASTFEELVYHLRHLITLLKSKSPETKVDYARLSEDLYWFLRDYQERVRLSWARDYYKRNFKGEKDNDK
>NZ_LS483381.1|WP_021673649.1|845945_847619_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MSRFNLLDEPWLSVVVDDKGSTKEVSLLDLFINAHQYKDLAGDTKTQDFAVLRVLLAVLHTVFSRFDADGNPYDYLEIDERFRQIEEVEEDDIDKYEEDLYDTWTNLWEQGKFPEIISQYLEKWRDRFYLFDDDYPFFQVKMKVLQKKFDLSNKLGELTGKTMNRLISESGNKAALFSPRADLDNNKEKLSEPEIVRWLLTYHSSTEVGGRLKSLGSTTSSGWLFRKGGIYFKGTNLFETLLMNCILPYKEYNNLKHTQKPCWEYEYLEIIQNYFDEVEPDNIASLYTTWSKGVDIDAKLNLPYFKCNIIKLPSINCEDYFLEPMTLWKYQDKIGKFIPKEHTINQSLWRSFGLLTENSSGKNYRTPGVINWFREIKNEIAKDKLVSICAVGVEMKSDANHTISDEITDYLFINEFVLADLEEGGWIPRINDTVEETKKVISRTYKRYIDDIKEIRKARSDLFTSQKVEELYFKIDQPFRQWLASLQPNDEKDTRVLEWREILDELVREEAELTLHSGGPRDYIGIVKRDPNKDSSEFINIATAYNKFNYCLNQNLK
>NZ_LS483381.1|WP_109982547.1|838218_842883_+|KxYKxGKxW-signal-peptide-domain-containing-protein
MEKKLHYKLHKVKKHWVTIAVASIGLVSLVGAGTVSAEDKVANDTTAQATVGVDTGQGQATTNDANTNTTDTDTSDQSANTNQDQAGSNQSNNQDQAKQDTANTDQNQADNSQTDNNQATDQATSPATDGTSVQRRDAANVATAADQEGQTDPSEQEKSAALSLDNVKLIDGKYYYIQADGSYKKNFAITVNGQMLYFDSDTGALSSTSTYSFSQGTTNLVDDFSSHNKAYDSTAKSFELVNGYLTANSWYRPVDILRNGQTWEASNENDLRPVLMSWWPDKDTQVAYVNYMNKYLSANETEVTNETSQVDLNKEAQSIQTKIEQKITSDNSTQWLRTAMEAFVAAQPKWNMSTENFNKGDHLQGGALLYTNSDLTPWANSDYRLLNRTPTQQDGTKKYFTEGGEGGYEFLLSNDVDNSNPVVQAEQLNQLHYLMNWGDIVLGDKDANFDGVRVDAVDNVNADLLQVYSNYFKDNYKVTDSEANALAHISILEAWSLNDNQYNEDTNGTALSIDNSSRLTSLAVLTKQPGQRLDLSNLISESVNKERANDTAYGDTIPTYSFVRAHDSEVQTVIAKIVKEKIDTNSDGYTFTLDQLKDAFKIYNEDMAKVNKTYTHYNIPAAYALLLSNMESVPRVYYGDLYTDDGQYMAKKSPYYDAIATMLQGRIAYVSGGQSEEVHKVNGNNQILSSVRYGQDLMSADDTQGTDLSRTSGMVTLVSNDPNLNLGSDSLTVNVGKAHANQAYRPLILGTKDGVQSYLKDSDTNIVKYTDANGNLTFTADDIKGYSTVDMSGYLAVWVPVGAKDGQDVRVAADTNQKADGKSLKTSAALDSQVIYEGFSNFQDFANNDADYTNKKIAENADFFKKLGITSFEMAPQYVSATDGSFLDSIIENGYAFSDRYDLAMSKNNKYGSKDDLANALKALHANGIQAIADWVPDQIYQLPGEEVVTAKRTNSYGKPTFDAFINNTLYAANTKSSGSDYQAQYGGAFLDELKAKYPDMFSVNMISTGKPIDSSTKIKQWEAKYFNGTNVLGKGAGYVLSDDATGKYFTVNENGDFLPASFTGDQNAKTGFYYDGTGMTYYSTSGNKAVDSFVYEGGHYYYFDKDGHMVTGSYKAVDGNDYYFLPNGIQMRDAIYQDDKGNSYYYGRTGILYKGDNWYPFTDPKNSNKTVFRYFDANNVMAIGYKDMYGQTYYFDENGYQAKGELLTDAKGTHYFDEDNGAMAKNKFVNVGDDWYYMDGNGNAVKGQYPVDNQILYFNPETGVQVKGQFITDAQGRISYYDGNSGALKSSGFFTPNGSDWYYAENGYVYKGFKQVAENQDQWYYFDQTTGKQAKGAAKVDGRDLYFNPDSGVQVKGDFATDESGNTSFYHGDNGDKVVGGFFTTGNNAWYYADNNGNLVKGFQEIDGKWYHFDEVTGQQAKGAALVNGQQLYFDVDSGIQVKGDFVTDGQGNTSYYDVNSGDKKVNGFFTTGDNAWYYADGQGNLAKGRKSIDNQDLYFDPATGKQVKGQLVSIDGRNYYFDSDSGNMAKNRFVRIGDQWIYFGNDGAATNL
>NZ_LS483381.1|WP_002962195.1|837186_837780_+|restriction-endonuclease-subunit-S
MKLIEDYLANPVKKLPLGQVARAFKGKAVSGKADPGRISYINLSDMTEFGIDYDHLKTFDDEQDKLQKYLLETGDVLVASKGTVKKVAVFEGQDFPIVASSNITVLRPIEELNGFYLKLFLESDLGQALIDTADKGKAVLNISTAQLLEIPVPQIPLVKQNYLVQYAYKGQADYERKLARAQQEWEHIKQEVAKNLF
>NZ_LS483381.1|WP_002962196.1|836397_836901_+|thiol-peroxidase
MPTFFGEPVTIAIDKQFQVGDIAPDFTLMASDLSQKSLSDFAGKKKVLSIVPSIDTGVCSTQTRIFNKELSELADTVVITVSADLPFAQEKWCGVQGLDEAIMLSDYYDNHFGQAYGVLMEEWHLLARAVLVLDEKNKITYTQYLDNINSEPDYQAAIAAVKALKSL
>NZ_LS483381.1|WP_109982549.1|853449_854805_+|Nramp-family-divalent-metal-transporter
MESPKNNYRANKASLSEVNQSVAVPETASFWRTLKAFIGPGALVAVGYMDPGNWITSVVGGASYKYLLLSVVLISSLMAMQLQQMAGKLGIVTRQDLAQATANHLPVWLRYILFVIIELALMATDLAEVIGSGIALHLLFGWPLMLSIFVTILDVFLLLGLMKLGFRKIEAVVSTLIMTILLIFVYLTVISQPSISGIFKGFVPSASIFDLQQTGANSKLTLALGIIGATVMPHNLYLHSSISQTRRVDYDNPESIRRAVRFMTWDSNIQLSLAFIVNSLLLILGAALFYGHASEISAFAQMYNALADPKIAGSVASGLLSTLFAVALLTSGQNSTITGTLTGQIVMEGFVHLRLPQWFIRLVTRLLALLPVILAALIWGSREKVLDQLIVYSQVFLSLALPFSIFPLIYFTSSKKLMGEHKNAIWNTALAYGVAVILTILNIKLIIDLFQ
>NZ_LS483381.1|WP_109982550.1|854983_859093_+|KxYKxGKxW-signal-peptide-domain-containing-protein
MEKNLRYKLHKVKKQWVAIGVTTVTLSFLAGGQVVAADTNNNDGTSVQVNKMVPSDPKFDAQAQNGQLAQAMFKAANQADQTATSQVSPATDGRVDNQATPAANQPAANVANQDVANQAANAGDLNRQSAADTSTDGKALPQTKDQPGHLETVDGKTYYVDANGQRLKNYSTVIDGKTYYFDGQTGQAQTDLPKTGQDNQQNVPDSYVANNQAYSNEASSFEAVDNYLTADSWYRPRKILKNGQSWQASSEGDLRPILMTWWPDAATKAAYANFWAKEGLISGSYRQNSANLDAATQNIQVAIEKKIAAEGNTNWLRDKMSQFVKLQNQWNSASEDKTDYPNQDHLQGGALLFSNSDATPQANSDWRLLNRNPTNQTGQQKYFKTNYAGYELLLANDVDNSNPIVQAEQLNQFHYLMNWGEIVMNDKDANFDGVRVDAVDNVDADLLQIQRDYYKARYGTDQNEKNAIDHLSILEAWSGNDNDYVKDQNNFSLSIDNDQRSYMLAAFANPANKRGNYLGQLATVGLKNRTGNNNSDPVPNYVFIRAHDSEVQTRIAKIIREKLGKTNADGLTNLTLDDLNKAFDIYNQDMNSVDKQYYPNNLPMAYAWMLQNKDTVTRVYYGDMYTDNGQYMETKTPFYNAIEALLKGRIKYVAGGQAVGYNQWNRVLTSVRYGKGANSINDAGDATTRNSGMALLINNQPNFRANSNITLNMGAAHRNQAYRPLLLSTQNGTATYLNDSDVNSSQYKYTDGQGRLTFNASEFRGVSNVQVSGMIQVWVPVGAAADQDVRTAPSTSATRDGNIYHQSDALDSQVIYEGFSNFQAFAQNPDQYTNAVIAKNADLFKSWGITQFEMAPQYVSSEDGTFLDSVIFNGYAFSDRYDLAMSKNNKYGSKQDLANAIKGLHAAGIKVLADWVPDQMYNLPGKEVVTATRVDEYGRTRSGATINKTPYVVNTKTYGDYQEQYGGKFLNDLQKLYPSLFTTKQISTGKPIDPSVKITNWSAKYFNGSNILGRGAKYVLSEGNKYLNLTGGKLFLPTVLNNTYGQPQASSKGFVSKADGIHYLDENGQEVKNQFKEIAGSWYYFDANGKMATGQTKVGDDTYLFMPNGKQLKEGILYDGNKAYYYDNNGRTWTNKGFVEFRVNGQDKWRYFNGDGSIAIGLVTLDNRTLYFDAYGYQVKGQTVTINGKSYTFDADQGDLEKTDNQDNPNPAPDNQGGWESLGDNQWGYRRNGKLLTGHQTIDGHQVFFQDNGVQVKGGTAKDASGVLRFYDRDQGRQAGKGWYSTSDNNWVYVDDSGKVLTGLQDINGQTVYFDENGIQAKGKGVWDNNGGLRYFEADSGNMIRDRWKNVDGTWYYFNRDGLASYYRW
>NZ_LS483381.1|WP_109982551.1|859398_863925_+|KxYKxGKxW-signal-peptide-domain-containing-protein
MERKLHYKLHKVKKQWVTIAVASAGLASIVGAGSVGQTVSADDLAQDQSSASEQKAASDQKQEEVASDAANTASAKVTSEKEVSQASDTTSESSQVQSQDQASAKQASDLAPATKAAPQAESQAGTSTASSEAAPAASSQEVAKSTTGSVSQNEEAAALSLANIKKIDGKFYYVMADGSYKKNFAITVDGQMLYFDAKTGALSSTSTYSFSQGLTPIVSDFSVNNKAFDSSEKSFELVDGYLTAESWYRPAKILENGKTWVDSKETDLRPVLMSWWPNKDTQVAYLNYMSKALGGKEEFTTETSQLTLNTAAELIQAKIEARVSKEQGTKWLREAMAAFVATQSRWNKDSEQYDKADHLQGGALLYTNNNLTEWANSNWRLLNRTPTRQDGKTHYSKADKYGGYEFLLANDVDNSNPVVQAEMLNQIHYLMNWGEIVMGDKNANFDGIRVDAVDNVNADTLQLYTNYFNSVYGVNKSEAQALAHISVLEAWSYNDNDYNQDTNGAALAMDNGLRFSLLYTLTRPINERTPGMSTLIKSEYGLTDRTKNDKYGDTQPSYVFVRAHDSEVQTVIAQIIKEKIDPTTDGFTFTLDQLKQAFEIYNKDMNSVNKHYTHYNIPAAYAVMLSNMESVTRVYYGDLFTDDGQYMASKSPYYDAINTLLRARIRYAAGGQIMEHNSYKPSAAMKAAHPDAGNVLGNSEVLVSVRFGQDVMSADDMTGGKLAKTSGMFTLISNNPELELDVNEEIKVNVGKIHAGQAYRPLLLTTDKGLQKYLNDSDTKLTKVADKDGFITFKGSEIKGYKQVEVNGYLSVWVPVGAKADQDIRVAPSTAAKGEKAKTYTASQALESQLIYEGFSNFQDFVQKDSQYTNKKIAENTDLFKAWGVTSFEMAPQYVSATDGTFLDSIIENGYAFTDRYDLAMSKNNKYGSKEDLANALKALHAAGIQAIADWVPDQIYQLPGKEVVTASRVDNYGRVKVDQPLVEKLYLANTKSSGKDFQAKYGGEFLAELQKKYPEMFTTKMISTGKTIDPSVKLKEWSAKYFNGTNVLDRGTDYVLSDEGTGKYFTVNENGDFLPASLTGNKDAKTGFYNDGKGIVYYTTAGNKAKSAFVTEAGNTYYFDYTGHMVTGPNVINTKFYYFLPNGVMLKDAIKQDEKGRSVYYGKTGVMYKGGRDNEWFAMTDSKGQMRFRHFDNYGFMSMGLVTIHGNVQYYDEEGFQVKGEFVTDKDGQTRYFDQGSGNLVKGQFLNKDGNWYYLDDQGLVAKGAQTIKGQKLYFDTKTGVQVKGDFVTDKDGNTFFYSGDTGDLILGQFFSTGNNAWFYADENGHVAKGAKTIRGQKLYFDTKTGQQAKGRFIRDDKGVRYYDADTGTLVTNAFLETKAGSNQWYYMGADGYAVKGNQTIKNQHMHFDAETGQQAKGIIVTDANGRKYFYDTFTGSRVVNQFVLVNGNWYFFGYDGAAVTGFHDIKGQHLYFNSDGTQAKGTTVKIGNRSYTFDAHTGELTSVHYG
>NZ_LS483381.1|WP_002959652.1|864173_864494_+|hypothetical-protein
MKSPIKKILFTSALVAAIFAAGSSVSALGVTETNRYGRAENPNLHRTFYDYNVHNMDINGNPIQEQGTDFSQYYWRGDESGSTTSYDENTHVTTTITYTVRYWEAK
>NZ_LS483381.1|WP_002959651.1|864655_864886_+|DUF1858-domain-containing-protein
MTNTIDLSRPVAEILEEHPELKDILLELGFKPLANPLMLKTLGRTTSLKAGSKLAKIPLEKIKQTLEFNGYEVKGD
>NZ_LS483381.1|WP_021673823.1|864887_866297_+|DUF438-domain-containing-protein
MAEERIEILKDILLDLHQGSSPEAVQERFDRTFKGVSALEISLMEHELMSDEKSGVTFEDVMDLCDVHANLFKNAVQGVEVADSDQPGHPVYVFKQENLALRGALLRIRRLLENLAQPENEEFQTDILKGLKNQIRLLGQFRRHYQRKEELFFPIMESYGHDSPPRVMWGVDDEIRQLFKDFQTKVEELPALEISIVRQSFEAFADEFEQMIFKEESILLMILLEIFTQDDWLKIAEESEAVGYAIVKPEEVWIPKRESFEPNQPSPADSNQLERDSKVVDEQTSKQSQANNPRPLDWDATNKQEQIIETPAGQFTLTFEPRKEALDRQVPQKFTNGYLSLDQANLILDHLPLEVTFVNKDDIFQYYNNSVSAKDMIFKRVPSQIGRNVELCHPPRVLDKVKKVFELLKTGQKDKVTMWFKSQKKGKFVYVTYAAVRDQAGEFQGVLEYVQDIQPFFDLEGDSQRDIID
>NZ_LS483381.1|WP_019775920.1|866372_867257_+|tRNA-pseudouridine(55)-synthase-TruB
MINGIINLKKEAGMTSHDAVFKLRKILGEKKIGHGGTLDPDVTGVLPIAVGKATRVLEYMTESGKVYEGQITLGYSTTTEDASGELVRETPVTQEQLTEEAVDQAMATFLGEITQVPPMYSAIKVNGRRLYDYARAGEEVERPHRQVTISEFARISPLSFENGLCRFDFRVACSKGTYVRTLAVDLGVELGLASHMSALRRTASAGLVLEKSFSLAEIADQLERGEADFLLPLEYGVLDLPRVELEKAQKTEISFGRFIRLDSQEAILAAFYEDRVQAILERRGYLYKPRKVLI
>NZ_LS483381.1|WP_019773967.1|867262_868180_+|bifunctional-riboflavin-kinase/FAD-synthetase
MKIIEIDSYQAIEQEEATVLVLGYFDALHRGHKVLFDKAREIAKRDQLKIAVLTFFESPKLAFARFEPDLLKHITYPEKRYAKFADYGVDYLYLTNFTTAFSQISSDDFIKDYLGQLKAKAVVVGFDYKFGHNRTDADYLARNFSGPVYTVAEVSQDGQKISSTRIRHLIAQGDVAKVNQLLGYEFSTRGIVVHGDARGRTIGFPTANLATLDRTFLPADGVYVTDVLLKGQRYRAMTSIGKNVTFGGTELRLEANIFDFSGDIYGEELEIIWLNKIREMVKFNGIDDLVDQLHQDQKIAKEWTL
>NZ_LS483381.1|WP_002959644.1|868419_868833_+|Spx/MgsR-family-RNA-polymerase-binding-regulatory-protein
MITLFLSPSCTSCRKARSWLTNHEVAFQEHNIITSPLSADELRAVLALTENGTEDIISTRSKVFQKLDLDVDDLSISELIDLIAKNPSLLRRPIILDKKRMQIGFNEDEIRAFLPRHYREQELRQATIRAELESDHD
>NZ_LS483381.1|WP_002959642.1|868825_869104_+|UPF0223-family-protein
MTKNYSYPLDASWSTEEIASVLYFLNQVEAAYESKAKTETLLEAYRSFKRVVPSKMQEKQIDREFEKSSGYSSYRAVQAARINAGGWVSLER

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_LS483381_1	1.1\|448605\|26\|NZ_LS483381\|CRISPRCasFinder	448605-448630	26	NZ_CP053834	Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence	159084-159109	6	0.769
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	192737-192768	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	192779-192810	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NC_049439	Salmonella phage SenASZ3, complete genome	13096-13127	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NC_016073	Salmonella phage SFP10, complete genome	89771-89802	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NC_027119	Salmonella phage Det7, complete genome	22868-22899	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	KY000003	Salmonella phage STP07, complete genome	113270-113301	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	MT074475	Salmonella phage dinky, complete genome	46249-46280	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	MH709120	Salmonella phage SeSz-3, complete genome	13096-13127	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	MN871500	UNVERIFIED: Salmonella phage Se-S, complete genome	91813-91844	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	KX171211	Salmonella phage vB_SenM-2, complete genome	22868-22899	8	0.75
NZ_LS483381_2	2.9\|853072\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	853072-853103	32	NC_031045	Salmonella phage GG32, complete genome	128973-129004	8	0.75
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	MN694191	Marine virus AFVG_250M444, complete genome	25897-25928	8	0.75
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	MN694065	Marine virus AFVG_250M443, complete genome	30835-30866	8	0.75
NZ_LS483381_2	2.3\|852705\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	852705-852736	32	NC_031062	Erwinia phage vB_EamP_Frozen, complete genome	17077-17108	9	0.719
NZ_LS483381_2	2.3\|852705\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	852705-852736	32	KX098391	Erwinia phage vB_EamP_Gutmeister, complete genome	13100-13131	9	0.719
NZ_LS483381_2	2.3\|852705\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	852705-852736	32	KX098390	Erwinia phage vB_EamP_Rexella, complete genome	16892-16923	9	0.719
NZ_LS483381_2	2.3\|852705\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	852705-852736	32	KF806588	Erwinia phage Ea9-2, complete genome	17499-17530	9	0.719
NZ_LS483381_2	2.6\|852889\|32\|NZ_LS483381\|PILER-CR,CRISPRCasFinder,CRT	852889-852920	32	NC_008043	Ruegeria sp. TM1040 megaplasmid, complete sequence	336350-336381	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	LC494302	Escherichia phage SP27 DNA, complete genome	312993-313024	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	MK817115	Escherichia phage vB_EcoM_phAPEC6, complete genome	163545-163576	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	NC_027364	Escherichia phage PBECO 4, complete genome	317674-317705	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	MH383160	Escherichia phage UB, complete genome	30812-30843	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	MK327931	Escherichia phage vB_EcoM_G17, complete genome	188849-188880	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	254502-254533	10	0.688
NZ_LS483381_2	2.12\|853255\|32\|NZ_LS483381\|CRISPRCasFinder,CRT	853255-853286	32	KM507819	Escherichia phage 121Q, complete genome	313629-313660	10	0.688

1. spacer 1.1|448605|26|NZ_LS483381|CRISPRCasFinder matches to NZ_CP053834 (Arcobacter cloacae strain LMG 26153 plasmid pACLO, complete sequence) position: , mismatch: 6, identity: 0.769

tttcatttccaacttttgacagtctc	CRISPR spacer
tttcatttacaacttttgacatctct	Protospacer
******** ************ ....

2. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
ggcaagcgttctttcatttcctgctcagccaa	Protospacer
  ***********  ********** * . **

3. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
ggcaagcgttctttcatttcctgctcagccaa	Protospacer
  ***********  ********** * . **

4. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_049439 (Salmonella phage SenASZ3, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

5. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_016073 (Salmonella phage SFP10, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

6. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_027119 (Salmonella phage Det7, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

7. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to KY000003 (Salmonella phage STP07, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

8. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to MT074475 (Salmonella phage dinky, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

9. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to MH709120 (Salmonella phage SeSz-3, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

10. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to MN871500 (UNVERIFIED: Salmonella phage Se-S, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

11. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to KX171211 (Salmonella phage vB_SenM-2, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

12. spacer 2.9|853072|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_031045 (Salmonella phage GG32, complete genome) position: , mismatch: 8, identity: 0.75

tccaagcgttcttggatttcctgctgattaaa	CRISPR spacer
tccaagcgttggtggatttcctgaaaaccaat	Protospacer
**********  ***********  .*..**

13. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to MN694191 (Marine virus AFVG_250M444, complete genome) position: , mismatch: 8, identity: 0.75

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
tatacttgggatgataactggtacgaagacga	Protospacer
 .* .* ****** ************* ** *

14. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to MN694065 (Marine virus AFVG_250M443, complete genome) position: , mismatch: 8, identity: 0.75

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
tatacttgggatgataactggtacgaagacga	Protospacer
 .* .* ****** ************* ** *

15. spacer 2.3|852705|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_031062 (Erwinia phage vB_EamP_Frozen, complete genome) position: , mismatch: 9, identity: 0.719

agaataccatccacctgagtagtagcgagagg	CRISPR spacer
cacgtaccatccacctgagcagtagggatatc	Protospacer
 . .***************.***** ** *

16. spacer 2.3|852705|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to KX098391 (Erwinia phage vB_EamP_Gutmeister, complete genome) position: , mismatch: 9, identity: 0.719

agaataccatccacctgagtagtagcgagagg	CRISPR spacer
cacgtaccatccacctgagcagtagggatatc	Protospacer
 . .***************.***** ** *

17. spacer 2.3|852705|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to KX098390 (Erwinia phage vB_EamP_Rexella, complete genome) position: , mismatch: 9, identity: 0.719

agaataccatccacctgagtagtagcgagagg	CRISPR spacer
cacgtaccatccacctgagcagtagggatatc	Protospacer
 . .***************.***** ** *

18. spacer 2.3|852705|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to KF806588 (Erwinia phage Ea9-2, complete genome) position: , mismatch: 9, identity: 0.719

agaataccatccacctgagtagtagcgagagg	CRISPR spacer
cacgtaccatccacctgagcagtagggatatc	Protospacer
 . .***************.***** ** *

19. spacer 2.6|852889|32|NZ_LS483381|PILER-CR,CRISPRCasFinder,CRT matches to NC_008043 (Ruegeria sp. TM1040 megaplasmid, complete sequence) position: , mismatch: 10, identity: 0.688

ggtctatctggtcaaggttcttgacagaagta	CRISPR spacer
caattatctgatcaaggttcatgacagcccaa	Protospacer
 . .******.********* ******    *

20. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

21. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to MK817115 (Escherichia phage vB_EcoM_phAPEC6, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

22. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

23. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

24. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

25. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

26. spacer 2.12|853255|32|NZ_LS483381|CRISPRCasFinder,CRT matches to KM507819 (Escherichia phage 121Q, complete genome) position: , mismatch: 10, identity: 0.688

ggttttggggatgctaactggtacgaatacta	CRISPR spacer
gacccgatggatgctaactggtatgaaaactt	Protospacer
*.... . ***************.*** ***

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

487548 : 496432

Streptococcus_phage(71.43%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_109982450.1\|487548_488643_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.0e-165	79.1
WP_109982451.1\|488682_489231_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	5.5e-59	60.7
WP_109982452.1\|489562_490741_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	4.1e-176	78.2
WP_019770871.1\|490817_491048_+	hypothetical protein	NA	NA	NA	NA
WP_109982453.1\|491044_491578_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	8.3e-44	52.1
WP_109982454.1\|491552_491909_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.1e-35	59.8
WP_109982455.1\|492023_492887_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_109982456.1\|493228_493654_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	2.6e-16	36.0
WP_162564131.1\|494115_494265_+	hypothetical protein	NA	NA	NA	NA
WP_109982457.1\|494824_496432_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.0e-12	25.2

DBSCAN-SWA_2

956115 : 1005989

Lactococcus_phage(11.11%)

protease,bacteriocin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019771729.1\|956115_956310_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_019770705.1\|956366_956558_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_019770704.1\|956585_956771_+	hypothetical protein	NA	NA	NA	NA
WP_019768643.1\|958477_958621_+	hypothetical protein	NA	NA	NA	NA
WP_109982564.1\|958652_959057_+	hypothetical protein	NA	NA	NA	NA
WP_032672939.1\|959106_960141_+	thiol reductase thioredoxin	NA	NA	NA	NA
WP_109982565.1\|960424_960850_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	3.8e-15	34.4
WP_002960740.1\|961713_962154_+	hypothetical protein	NA	NA	NA	NA
WP_002960737.1\|962309_962567_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_109982566.1\|962602_962899_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_002960733.1\|963457_963922_+	hypothetical protein	NA	NA	NA	NA
WP_109982567.1\|964342_965494_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_019768632.1\|965499_966204_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-32	38.9
WP_019771636.1\|966216_967458_+	ABC transporter permease	NA	NA	NA	NA
WP_109982568.1\|967936_969157_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_019770995.1\|969140_969986_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_109982569.1\|970050_970863_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_019785392.1\|971208_971556_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_080566235.1\|971654_971966_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002960712.1\|972131_972404_+	30S ribosomal protein S16	NA	NA	NA	NA
WP_002960710.1\|972415_972655_+	KH domain-containing protein	NA	NA	NA	NA
WP_019768628.1\|973241_973886_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_002960707.1\|973882_974416_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_109982570.1\|974447_975425_+	BtrH N-terminal domain-containing protein	NA	NA	NA	NA
WP_002963266.1\|976266_976470_-	CsbD family protein	NA	NA	NA	NA
WP_109982571.1\|978207_978669_-	DUF3290 domain-containing protein	NA	NA	NA	NA
WP_002959661.1\|979215_979737_+	ribosome maturation factor RimM	NA	NA	NA	NA
WP_029236964.1\|979726_980467_+\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_109982572.1\|980459_981458_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.4e-31	54.0
WP_021673334.1\|982152_982869_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002963242.1\|983274_983988_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002963243.1\|983984_984896_+	1-phosphofructokinase	NA	NA	NA	NA
WP_109982573.1\|984892_986851_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_019769661.1\|987017_987713_+	DNA repair protein RadC	A0A1B2LRS6	Wolbachia_phage	1.1e-14	26.1
WP_002963247.1\|987854_988547_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_019771210.1\|988627_989266_-	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_002963250.1\|989544_989892_-	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_019775638.1\|989901_991023_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	8.1e-25	27.2
WP_002963254.1\|991024_991990_-	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	1.6e-37	35.1
WP_019772755.1\|992945_993518_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_002963163.1\|993647_994313_+	GTP pyrophosphokinase family protein	NA	NA	NA	NA
WP_019771073.1\|994287_995130_+	NAD kinase	NA	NA	NA	NA
WP_002963161.1\|995126_996017_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_109982575.1\|996033_997017_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_002963159.1\|997151_997907_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002963158.1\|997926_998109_+	hypothetical protein	NA	NA	NA	NA
WP_002963157.1\|998205_998592_-	hypothetical protein	NA	NA	NA	NA
WP_109982576.1\|998738_999584_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_002963151.1\|999779_1000670_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_019777081.1\|1000822_1001734_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_019777082.1\|1001739_1002906_-	hydroxymethylglutaryl-CoA synthase	NA	NA	NA	NA
WP_019775453.1\|1003105_1003945_+	thymidylate synthase	U5J9N5	Bacillus_phage	2.1e-81	52.5
WP_109982577.1\|1004028_1004550_+	dihydrofolate reductase	A0A1B2IFI7	Erwinia_phage	9.3e-16	30.7
WP_002961893.1\|1004564_1004735_+	hypothetical protein	NA	NA	NA	NA
WP_019781461.1\|1004756_1005989_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-134	59.4

DBSCAN-SWA_3

1256720 : 1264116

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021673864.1\|1256720_1257398_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.3e-89	69.3
WP_019770326.1\|1257405_1258566_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	6.9e-152	69.1
WP_109982644.1\|1258683_1260837_+	LTA synthase family protein	W6LM83	Streptococcus_phage	1.6e-263	68.5
WP_002959127.1\|1261101_1261719_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002959130.1\|1261887_1262202_-	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
WP_002959132.1\|1262318_1262639_-	phosphoribosyl-AMP cyclohydrolase	A0A2H4UVM0	Bodo_saltans_virus	2.6e-08	30.8
WP_002959135.1\|1262635_1263394_-	imidazole glycerol phosphate synthase subunit HisF	A0A2H4UVM0	Bodo_saltans_virus	2.8e-05	24.7
WP_002959136.1\|1263396_1264116_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	A0A2H4UVM0	Bodo_saltans_virus	2.8e-10	24.8

DBSCAN-SWA_4

1474512 : 1546095

Staphylococcus_phage(15.38%)

bacteriocin,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111687991.1\|1474512_1475448_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.0e-85	54.0
WP_019778096.1\|1475660_1476413_-	esterase family protein	NA	NA	NA	NA
WP_019771498.1\|1476999_1478178_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_019768798.1\|1478340_1478994_+	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	1.7e-67	56.2
WP_032672889.1\|1480641_1483323_-	cation-translocating P-type ATPase	M1IAU8	Acanthocystis_turfacea_Chlorella_virus	2.0e-69	28.9
WP_094966369.1\|1483538_1484708_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_021673557.1\|1484762_1485662_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_109982686.1\|1485711_1486950_-	four-carbon acid sugar kinase family protein	NA	NA	NA	NA
WP_019775781.1\|1487110_1487359_+	PrpR N-terminal domain-containing protein	NA	NA	NA	NA
WP_109982687.1\|1487461_1488892_+	PrpR N-terminal domain-containing protein	NA	NA	NA	NA
WP_002961446.1\|1489010_1489400_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_109982688.1\|1489529_1490822_+	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	7.7e-27	31.8
WP_002962978.1\|1491435_1492245_+	sugar-phosphatase	NA	NA	NA	NA
WP_002962976.1\|1492244_1493459_+	aminoacyltransferase	NA	NA	NA	NA
WP_021673553.1\|1493455_1494688_+	aminoacyltransferase	NA	NA	NA	NA
WP_111687997.1\|1494763_1495699_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	4.5e-85	54.0
WP_019768808.1\|1496045_1496210_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_019768809.1\|1496512_1497175_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_019771007.1\|1497284_1498043_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_021673940.1\|1498140_1498875_-	histidinol phosphate phosphatase HisJ family protein	NA	NA	NA	NA
WP_019773116.1\|1499826_1500585_+	glucosaminidase domain-containing protein	Q9ZXE4	Bacillus_phage	1.4e-17	40.5
WP_019768890.1\|1500692_1502123_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_019768891.1\|1502345_1504079_-	phosphoenolpyruvate--protein phosphotransferase	NA	NA	NA	NA
WP_002961321.1\|1504083_1504347_-	phosphocarrier protein HPr	NA	NA	NA	NA
WP_002961320.1\|1504870_1505095_+	glutaredoxin-like protein NrdH	A0A0M7REK7	Lactobacillus_phage	5.9e-12	44.0
WP_019793466.1\|1505181_1507341_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.5e-258	61.8
WP_019768892.1\|1507807_1508767_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	5.9e-125	68.9
WP_002962434.1\|1508929_1509292_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_019770354.1\|1509295_1509991_+	LrgB family protein	NA	NA	NA	NA
WP_002962438.1\|1510245_1510407_+\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_002962440.1\|1510646_1511777_-	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	1.7e-22	27.0
WP_019770352.1\|1511826_1512561_-	acetylglutamate kinase	NA	NA	NA	NA
WP_109982689.1\|1512781_1513975_-	bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ	NA	NA	NA	NA
WP_109982690.1\|1514048_1515071_-	N-acetyl-gamma-glutamyl-phosphate reductase	NA	NA	NA	NA
WP_019768897.1\|1515315_1515840_-	hypothetical protein	NA	NA	NA	NA
WP_002963098.1\|1517164_1518820_-	DNA repair protein RecN	NA	NA	NA	NA
WP_002963099.1\|1518833_1519304_-	arginine repressor ArgR	NA	NA	NA	NA
WP_002963100.1\|1519290_1520118_-	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_002963101.1\|1520110_1520977_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_002963102.1\|1520969_1521194_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_019771965.1\|1521168_1522512_-	exodeoxyribonuclease VII large subunit	L7RDW5	Acanthamoeba_polyphaga_moumouvirus	4.2e-36	31.3
WP_019780220.1\|1523008_1523836_-	hypothetical protein	NA	NA	NA	NA
WP_002963105.1\|1524148_1524361_-	hypothetical protein	NA	NA	NA	NA
WP_094966362.1\|1524600_1525890_-	U32 family peptidase	Q6DW11	Phage_TP	7.9e-40	32.2
WP_002962142.1\|1527172_1527406_-	hypothetical protein	NA	NA	NA	NA
WP_002962143.1\|1527472_1527712_-	hypothetical protein	NA	NA	NA	NA
WP_109982691.1\|1528606_1529611_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_002962146.1\|1529795_1530680_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_019770346.1\|1530835_1532458_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_019789900.1\|1532477_1533749_+	2-hydroxycarboxylate transporter family protein	NA	NA	NA	NA
WP_019778054.1\|1533805_1534057_-	hypothetical protein	NA	NA	NA	NA
WP_019771068.1\|1534084_1534450_-	hypothetical protein	NA	NA	NA	NA
WP_002962157.1\|1534731_1536300_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.6e-58	37.7
WP_109982692.1\|1536669_1541370_-	antigen I/II family LPXTG-anchored adhesin	NA	NA	NA	NA
WP_019792648.1\|1541787_1542360_+	energy-coupled thiamine transporter ThiT	NA	NA	NA	NA
WP_019769916.1\|1543922_1544480_-	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_109982810.1\|1544700_1546095_+\|transposase	ISNCY family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_LS483381

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection